title: Endodermal sinus (yolk sac) tumor of oral cavity originating from gingiva.
abstract: Endodermal sinus tumor is a malignant germ cell tumor which usually arises in gonads. Extragonadal endodermal sinus tumors in the head and neck are very rare. Here a gingival endodermal sinus tumor is reported. The lesion demonstrated typical microscopic features of the endodermal sinus tumors of gonads. The tumor cells showed alpha-fetoprotein immunoreactivity in immunohistochemical evaluation. The serum alpha-fetoprotein level was high. This is the first gingival case in the related literature.
authors.affiliation: Department of Otolaryngology, School of Medicine, Yüzüncü Yil University, Van, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Kutluhan
authors.forename: S
authors.initials: S
authors.lastname: Uğraş
authors.forename: E
authors.initials: E
authors.lastname: Akman
mesh_terms: D001706:Biopsy; D018240:Endodermal Sinus Tumor / Q000097:blood / Q000276:immunology / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D005887:Gingival Neoplasms / Q000097:blood / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins