Definition of false-positive reactions in screening for hepatitis C virus antibodies.
The rate of false-positive hepatitis C virus enzyme immunoassay results was determined to be at least 10% among 1,814 reactive serum samples based on (i) negative results in an independent confirmation assay, (ii) negative PCR results, and (iii) no patients developing clinical or biochemical signs of hepatitis during a 1-year follow-up.
Schröter
M
M
Institut fur Medizinische Mikrobiologie und Immunologie, Universit äts-Krankenhaus Eppendorf, 20246 Hamburg, Germany. mschroeter@uke.uni-hamburg.de
Feucht
H H
HH
Schäfer
P
P
Zöllner
B
B
Polywka
S
S
Laufs
R
R
D005189:False Positive Reactions; D005500:Follow-Up Studies; D016174:Hepacivirus / Q000276:immunology*; D006526:Hepatitis C / Q000175:diagnosis*; D018937:Hepatitis C Antibodies / Q000032:analysis*; D006801:Humans; D015151:Immunoblotting; D007124:Immunoenzyme Techniques; D016133:Polymerase Chain Reaction / Q000379:methods; D012680:Sensitivity and Specificity; D012698:Serologic Tests
D018937:Hepatitis C Antibodies