title: Infrared studies of protein-induced perturbation of lipids in lipoproteins and membranes.
abstract: The paper reviews the main recent publications concerning infrared (IR) spectroscopy as applied to the study of lipid-protein interactions in model and cell membranes, lipoproteins, and related systems (e.g. lung surfactant). The review focuses mainly on transmission IR. Based on the available data, a number of general conclusions are presented on the perturbations caused by proteins on either the hydrocarbon chains, the polar headgroups or the interface region. Lipid-protein interactions in native cell membranes do not reveal significant differences from what is observed in semisynthetic model systems.
authors.affiliation: Departamento de Bioquímica, Universidad del País Vasco, Bilbao, Spain.
authors.forename: J L
authors.initials: JL
authors.lastname: Arrondo
authors.forename: F M
authors.initials: FM
authors.lastname: Goñi
mesh_terms: D000818:Animals; D006801:Humans; D008074:Lipoproteins / Q000737:chemistry*; D008563:Membrane Lipids / Q000737:chemistry*; D008565:Membrane Proteins / Q000737:chemistry*; D013055:Spectrophotometry, Infrared
chemical_list: D008074:Lipoproteins; D008563:Membrane Lipids; D008565:Membrane Proteins