title: Investigations of azapeptides as mimetics of Leu-enkephalin.
abstract: Solution syntheses of azapeptide pentamers 2, 3, and 4 were accomplished. The binding affinity of these azapeptides and azatide 1 were examined in the context of monoclonal antibody 3-E7 known to strongly bind the [Leu5]enkephalin sequence.
authors.affiliation: Department of Chemistry, Scripps Research Institute, La Jolla, CA, USA.
authors.forename: H
authors.initials: H
authors.lastname: Han
authors.forename: J
authors.initials: J
authors.lastname: Yoon
authors.forename: K D
authors.initials: KD
authors.lastname: Janda
mesh_terms: D004743:Enkephalin, Leucine / Q000737:chemistry* / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D018716:Molecular Mimicry; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000737:chemistry / Q000276:immunology; D011485:Protein Binding
chemical_list: D009842:Oligopeptides; D004743:Enkephalin, Leucine