title: Klebsiella pneumoniae clinical isolates: susceptibility to some antibiotics and surface hydrophobicity.
abstract: The susceptibility of Klebsiella pneumoniae strains isolated from the respiratory tract (55), urinary tract (19) and other human body sites (8) to the antibiotics, amoxycillin/clavulanate, cefuroxime, ceftazidime, gentamicin, norfloxacin, colistine, cotrimoxazole and oxolinic acid, as well as their surface hydrophobicity, were studied. The strains expressed a very high sensitivity to the antibiotics (94.7-100%). The surface hydrophobicity of the strains was evaluated by means of three assays and was minimal. The hydrophobicity manifested by adherence to xylene ranged between 0 and 10% for 96.4% of the respiratory strains, and for 100% of the urinary and other sites. Weak binding of Congo red (10-29 micrograms/10(10) cells) showed 96.4% of respiratory isolates as well as 100% of the urinary and other strains. Results of the salt aggregation test showed that 96.4% of respiratory strains and 100% of urinary and other strains aggregated only at 1.5 M, 2 M or higher concentrations.
authors.affiliation: Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic.
authors.forename: A
authors.initials: A
authors.lastname: Hostacká
authors.forename: E
authors.initials: E
authors.lastname: Síposová
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001422:Bacterial Adhesion / Q000187:drug effects*; D005260:Female; D006801:Humans; D007711:Klebsiella pneumoniae / Q000187:drug effects*; D012137:Respiratory System / Q000382:microbiology; D014551:Urinary Tract / Q000382:microbiology; D014621:Vagina / Q000382:microbiology; D014947:Wounds and Injuries / Q000382:microbiology; D014992:Xylenes / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D014992:Xylenes