title: Appearance of fosfomycin resistant Rahnella aquatilis clinically isolated in Japan.
abstract: Among recent clinical isolates in Japan, strain CU264 was discovered which formed unusual colonies. This strain was identified as Rahnella aquatilis which is usually found in water. The antibiotic susceptibilities against tetracycline, carbenicillin, chloramphenicol, streptomycin, kanamycin, gentamicin, sulphonamide, neomycin, fosfomycin, rifampicin, norfloxacin and nalidixic acid, were investigated. The result demonstrated that the strain was highly resistant to fosfomycin only. It was further shown that this resistance was transmissible with low frequency to Serratia marcescens whereas it was not transmissible to Escherichia coli.
authors.affiliation: Division of Microbial Chemistry, Faculty of Pharmaceutical Sciences, Chiba University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: O'Hara
authors.forename: J
authors.initials: J
authors.lastname: Chen
authors.forename: F
authors.initials: F
authors.lastname: Shigenobu
authors.forename: A
authors.initials: A
authors.lastname: Nakamura
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
authors.forename: M
authors.initials: M
authors.lastname: Shimojima
authors.forename: H
authors.initials: H
authors.lastname: Ida
authors.forename: E
authors.initials: E
authors.lastname: Yoshikawa
authors.forename: I
authors.initials: I
authors.lastname: Tsuboi
authors.forename: K
authors.initials: K
authors.lastname: Mizuoka
authors.forename: T
authors.initials: T
authors.lastname: Sawai
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D004926:Escherichia coli / Q000145:classification; D005144:F Factor / Q000032:analysis; D005578:Fosfomycin / Q000494:pharmacology*; D006801:Humans; D010641:Phenotype; D012706:Serratia marcescens / Q000145:classification; D014552:Urinary Tract Infections / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D005578:Fosfomycin