title: Anticytomegalovirus (anti-CMV) immunoglobulin G avidity in identification of pregnant women at risk of transmitting congenital CMV infection.
abstract: In this work, we show that the determination of the anticytomegalovirus antibody avidity carried out before week 18 of gestation is a helpful tool to identify women for enrollment in prenatal diagnosis. This procedure can identify all pregnant women who will give birth to an infected newborn.
authors.affiliation: Department of Clinical and Experimental Medicine, Section of Microbiology, Medical School, University of Bologna, Bologna, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Lazzarotto
authors.forename: P
authors.initials: P
authors.lastname: Spezzacatena
authors.forename: S
authors.initials: S
authors.lastname: Varani
authors.forename: L
authors.initials: L
authors.lastname: Gabrielli
authors.forename: P
authors.initials: P
authors.lastname: Pradelli
authors.forename: B
authors.initials: B
authors.lastname: Guerra
authors.forename: M P
authors.initials: MP
authors.lastname: Landini
mesh_terms: D000653:Amniotic Fluid / Q000821:virology; D000914:Antibodies, Viral / Q000097:blood*; D000915:Antibody Affinity; D016022:Case-Control Studies; D003587:Cytomegalovirus / Q000276:immunology* / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000150:complications / Q000151:congenital* / Q000635:transmission*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000276:immunology*; D011296:Prenatal Diagnosis; D012307:Risk Factors
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G