title: Questioning the efficacy of Fallopian tube sperm perfusion.
abstract: The aim of this work was to compare the efficiency of standard intrauterine insemination (IUI) and Fallopian tube sperm perfusion (FSP) in the treatment of infertility. Ninety-six consecutive patients with infertility in 100 cycles were included in the study. Those randomized to standard IUI included 48 patients in 50 cycles [25 clomiphene citrate only and 25 clomiphene citrate/human menopausal gonadotrophin (HMG) cycles] (group I). Patients subjected to FSP included 48 patients in 50 cycles (18 clomiphene citrate only and 32 clomiphene citrate/HMG cycles) (group II). The overall pregnancy rate per cycle (16% versus 18%) was not significantly different in the two groups. The pregnancy rates were also similar in the two groups when compared for the cause of infertility: ovulatory disorder 16.7% versus 16%, tubal impairment 10% versus 9.1%, cervical hostility (no pregnancy occurred in this group) and unexplained infertility 21.4 % versus 25 %. The overall pregnancy rate (for the two groups) appeared higher when clomiphene citrate/HMG was used for ovulation induction (21.1%) than when clomiphene citrate only was used (11.6%).
authors.affiliation: Department of Obstetrics and Gynecology, Cairo University, Egypt.
authors.forename: M M
authors.initials: MM
authors.lastname: El Sadek
authors.forename: M K
authors.initials: MK
authors.lastname: Amer
authors.forename: G
authors.initials: G
authors.lastname: Abdel-Malak
mesh_terms: D000293:Adolescent; D000328:Adult; D002996:Clomiphene / Q000627:therapeutic use; D005187:Fallopian Tubes; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D007315:Insemination, Artificial / Q000379:methods*; D008596:Menotropins / Q000627:therapeutic use; D010062:Ovulation Induction; D010477:Perfusion; D011247:Pregnancy; D016896:Treatment Outcome; D014599:Uterus
chemical_list: D002996:Clomiphene; D008596:Menotropins