title: [The effect of polyamine on the structure of the free amino acid pool in the blood plasma and in the liver of animals with chronic alcoholic intoxication].
abstract: The effect of polyamine on the total content of free amino acids and the structure of the amino acid fund in blood plasma and hepatic tissue was studied in rats with chronic alcoholic intoxication. Rapid utilization of exogenic introduced amino acids and a normalizing effect of the drug on the structure of the amino acid fund were demonstrated. The high concentration of aromatic amino acids in the drug may be among the causes of the increased content of this fraction of amino acids in the tissues studied after administration of the drug.
authors.affiliation: Laboratory of Medico-Biological Problems of Narcology, Grodno Medical Institute, Belarus.
authors.forename: V M
authors.initials: VM
authors.lastname: Sheĭbak
mesh_terms: D000437:Alcoholism / Q000188:drug therapy* / Q000378:metabolism; D000596:Amino Acids / Q000032:analysis / Q000187:drug effects* / Q000378:metabolism; D000818:Animals; D004353:Drug Evaluation, Preclinical; D008099:Liver / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D011073:Polyamines / Q000627:therapeutic use*; D051381:Rats; D013997:Time Factors
chemical_list: D000596:Amino Acids; D011073:Polyamines
vernacular_title: Vliianie poliamina na strukturu fonda svobodnykh aminokislot plazmy krovi i pecheni zhivotnykh s khronicheskoĭ akkogol'noĭ intoksikatsieĭ.