title: Contrast-enhanced magnetisation transfer MRI in metastatic lesions of the brain.
abstract: Our purpose was to compare prospectively the sensitivity of contrast-enhanced magnetisation transfer (MT) MRI and gradient-echo (GE) T1-weighted images in metastatic disease of the brain. We studied 52 patients with brain metastases, using conventional T1-weighted GE and MT spin-echo (SE) images after the same standard dose of gadolinium. Axial 5-mm reconstructions of GE data were compared with 5-mm MT images in the same plane. Metastases were counted independently by two neuroradiologists. In 12 patients (23%) MT imaging showed more metastases than GE images (P = 0.03). We detected 68 more metastases with the former technique.
authors.affiliation: Department of Neuroradiology, Hôpital de la Timone, Marseille, France.
authors.forename: P
authors.initials: P
authors.lastname: Peretti-Viton
authors.forename: D
authors.initials: D
authors.lastname: Taieb
authors.forename: J M
authors.initials: JM
authors.lastname: Viton
authors.forename: A
authors.initials: A
authors.lastname: Flori
authors.forename: X
authors.initials: X
authors.lastname: Muracciole
authors.forename: V
authors.initials: V
authors.lastname: Benguigui
authors.forename: G
authors.initials: G
authors.lastname: Salamon
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000473:pathology* / Q000556:secondary* / Q000628:therapy; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D005682:Gadolinium