title: Intraluminal mucin pool in mucinous gastric adenocarcinoma: a case report.
abstract: Mucinous gastric carcinoma is a rare pathologic subtype of gastric adenocarcinoma. Whether the mucin behaves aggressively as in mucinous colorectal carcinoma is still controversial. Most mucinous gastric carcinomas are diagnosed from surgical specimens. The mucinous gastric carcinoma in this case report was discovered preoperatively according to its characteristic presentation. An upper gastrointestinal endoscopic examination showed a round protruding tumor of greater than 4 cm in size on the mid-body of the stomach; it had an uneven, friable and shiny surface. The surface was coated with a sticky layer of mucin-like substance, which persisted even after the aspiration of the gastric juice. Endoscopic ultrasonography (EUS) revealed a large heterogeneous hyperechoic tumor mass, originating from the mucosal and submucosal layers, on the body of the stomach. The mass was covered with a thick layer of hypoechoic amorphous substance. Hence, a mucin-producing tumor was suspected. Subsequent surgical biopsy proved the mass to be a moderately differentiated mucinous adenocarcinoma. This case illustrates the first endoscopic ultrasonographic report of an intraluminal mucin pool as a hypoechoic substance, which is quite different from the hyperechoic presentation of intramural mucin lakes. In preoperative evaluation, EUS is not only important for determining the depth of tumor invasion, but it is also useful in differentiating mucinous gastric carcinoma from nonmucinous gastric carcinoma.
authors.affiliation: Department of Internal Medicine, Taichung Veterans General Hospital, Taiwan, ROC.
authors.forename: C Y
authors.initials: CY
authors.lastname: Wu
authors.forename: H Z
authors.initials: HZ
authors.lastname: Yeh
authors.forename: R T
authors.initials: RT
authors.lastname: Shih
authors.forename: G H
authors.initials: GH
authors.lastname: Chen
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000737:chemistry* / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D009077:Mucins / Q000032:analysis*; D013274:Stomach Neoplasms / Q000737:chemistry* / Q000000981:diagnostic imaging; D014463:Ultrasonography
chemical_list: D009077:Mucins