The effect of structural changes on swelling kinetics of polybasic/hydrophobic pH-sensitive hydrogels.
The effect of pendent side-chain length and crosslinking agent concentration in methyl methacrylate/dimethylaminoethyl methacrylate as a polybasic/hydrophobic pH-sensitive hydrogel was studied. Increasing both side-chain length and crosslinking agent concentration decreased the sharpness of response to pH and water-uptake capacity of the polymer. A case-II water transport mechanism and a nonlinear swelling kinetic was observed for the homologues of this hydrogel.
Falamarzian
M
M
Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Iran.
Varshosaz
J
J
D000468:Alkalies / Q000737:chemistry; D003432:Cross-Linking Reagents; D020100:Hydrogels / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D012044:Regression Analysis; D012995:Solubility; D014867:Water / Q000737:chemistry*
D000468:Alkalies; D003432:Cross-Linking Reagents; D020100:Hydrogels; D014867:Water