Autonomic neuropathies.
A limited autonomic neuropathy may underlie some unusual clinical syndromes, including the postural tachycardia syndrome, pseudo-obstruction syndrome, heat intolerance, and perhaps chronic fatigue syndrome. Antibodies to autonomic structures are common in diabetes, but their specificity is unknown. The presence of autonomic failure worsens prognosis in the diabetic state. Some autonomic neuropathies are treatable. Familial amyloid polyneuropathy may respond to liver transplantation. There are anecdotal reports of acute panautonomic neuropathy responding to intravenous gamma globulin. Orthostatic hypotension may respond to erythropoietin or midodrine.
Low
P A
PA
Mayo Medical School, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
D001323:Autoantibodies; D001342:Autonomic Nervous System Diseases / Q000276:immunology / Q000473:pathology / Q000628:therapy; D003929:Diabetic Neuropathies / Q000276:immunology / Q000473:pathology; D006801:Humans
D001323:Autoantibodies