title: The HD domain defines a new superfamily of metal-dependent phosphohydrolases.
authors.affiliation: NCBI, National Library of Medicine, NIH, Bethesda, MD 20894, USA. aravind@ncbi.nlm.nih.gov
authors.forename: L
authors.initials: L
authors.lastname: Aravind
authors.forename: E V
authors.initials: EV
authors.lastname: Koonin
mesh_terms: D000595:Amino Acid Sequence; D008025:Ligases / Q000737:chemistry / Q000378:metabolism; D008969:Molecular Sequence Data; D009713:Nucleotidyltransferases / Q000737:chemistry / Q000378:metabolism; D051922:PII Nitrogen Regulatory Proteins; D010727:Phosphoric Diester Hydrolases / Q000737:chemistry / Q000378:metabolism; D010744:Phosphoric Monoester Hydrolases / Q000737:chemistry* / Q000378:metabolism*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
chemical_list: D051922:PII Nitrogen Regulatory Proteins; D009713:Nucleotidyltransferases; C022515:regulatory protein uridylyltransferase; D010744:Phosphoric Monoester Hydrolases; D010727:Phosphoric Diester Hydrolases; D008025:Ligases; C028812:guanosine 3',5'-polyphosphate synthetases