title: Rupture of ectopic pregnancy after medical therapy with methotrexate: a case series.
abstract: Medical treatment of ectopic pregnancy with methotrexate has become the standard of care in many areas of the U.S. Rupture of ectopic pregnancy after medical treatment presents a diagnostic challenge to the Emergency Physician. We review a series of 11 patients with ectopic pregnancy treated with methotrexate who then required surgical treatment for rupture.
authors.affiliation: Emergency Medicine, Denver Health Medical Center, Colorado, USA.
authors.forename: K
authors.initials: K
authors.lastname: Heard
authors.forename: J
authors.initials: J
authors.lastname: Kendall
authors.forename: J
authors.initials: J
authors.lastname: Abbott
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000009:adverse effects* / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D004636:Emergency Service, Hospital; D005184:Fallopian Tube Diseases / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D007813:Laparotomy; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000188:drug therapy*; D011379:Prognosis; D012042:Registries; D012422:Rupture, Spontaneous / Q000209:etiology / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate