title: Comparison of open mitral commissurotomy with mitral valve replacement with or without chordal preservation in patients with mitral stenosis.
abstract: BACKGROUND
  Percutaneous balloon mitral valvuloplasty and durable mitral prostheses have made the role of open mitral commissurotomy (OMC) uncertain.
  
  
  RESULTS
  Results from the use of St Jude mitral valve replacement (SJMVR) were compared with those of the use of OMC in 312 consecutive patients with mitral stenosis between 1983 and the present. OMC and SJMVR patients were well matched for age, sex, and comorbidity except that SJMVR patients had more severe stenosis and were more likely to undergo concurrent aortic valve replacement. Compared with OMC, SJMVR without chordal preservation involved a longer pump time (158 +/- 81 versus 87 +/- 41 min, P < 0.05), more frequent in-hospital complications or death (57 of 219 [26%] versus 4 of 52 [8%], P < 0.01), and longer hospital stay (13 +/- 11 versus 10 +/- 6 days, P = 0.001). Preservation of chordae to at least 1 mitral valve leaflet decreased early morbidity and mortality rates of SJMVR to values comparable to those of OMC (3 of 41 [7%]). Survival was greater at 10 years for OMC versus SJMVR (86 +/- 5% versus 67 +/- 4%, P = 0.03). Ten-year freedom from cardiac events was not different between groups (49 +/- 9% for OMC versus 55 +/- 4% for SJMVR, P = 0.7). Freedom from subsequent mitral procedures at 10 years was better for SJMVR (96 +/- 2% versus 58 +/- 8%, P < 0.001).
  
  
  CONCLUSIONS
  In the modern era, SJMVR offers significantly greater durability than does OMC. Chordal preservation at the time of SJMVR may reduce perioperative complications to levels comparable to those of OMC.
authors.affiliation: Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA. glowe001@mc.duke.edu
authors.forename: D D
authors.initials: DD
authors.lastname: Glower
authors.forename: K P
authors.initials: KP
authors.lastname: Landolfo
authors.forename: R D
authors.initials: RD
authors.lastname: Davis
authors.forename: Y Y
authors.initials: YY
authors.lastname: Cen
authors.forename: J K
authors.initials: JK
authors.lastname: Harrison
authors.forename: T M
authors.initials: TM
authors.lastname: Bashore
authors.forename: J E
authors.initials: JE
authors.lastname: Lowe
authors.forename: W G
authors.initials: WG
authors.lastname: Wolfe
mesh_terms: D000328:Adult; D000368:Aged; D002815:Chordae Tendineae / Q000601:surgery*; D016002:Discriminant Analysis; D005260:Female; D006331:Heart Diseases / Q000453:epidemiology; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D008946:Mitral Valve Stenosis / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology; D016016:Proportional Hazards Models; D016019:Survival Analysis