title: Intrafamilial association of pericentric inversion of chromosome 9, inv (9)(p11-q21), and rapid cycling bipolar disorder.
abstract: Association of a chromosome aberration and psychiatric disorder can be useful in highlighting a genomic region that can be profitably explored further using positional cloning. We report the case of a father and daughter both of whom have bipolar disorder II and a pericentric inversion of chromosome 9.
authors.affiliation: Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, UK.
authors.forename: F
authors.initials: F
authors.lastname: McCandless
authors.forename: I
authors.initials: I
authors.lastname: Jones
authors.forename: K
authors.initials: K
authors.lastname: Harper
authors.forename: N
authors.initials: N
authors.lastname: Craddock
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001714:Bipolar Disorder / Q000150:complications / Q000235:genetics*; D002648:Child; D007446:Chromosome Inversion; D002899:Chromosomes, Human, Pair 9 / Q000235:genetics / Q000648:ultrastructure*; D019052:Depression, Postpartum / Q000209:etiology; D003865:Major Depressive Disorder / Q000235:genetics; D004410:Dyslexia; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D008297:Male; D010375:Pedigree