title: [Disorders of sex development in dogs].
abstract: In two prepubertal dogs of female phenotype, a clitoral enlargement with a penile structure leading to recurring inflammation of the vagina was diagnosed. Progesterone, oestrogen and testosterone serum concentrations were radioimmunologically analysed. The histology of the penile structure, the gonads and the uterus was made via a hematoxylin-eosin staining method. The chromosome constitution being analysed by the method of Basur and Gilman (1964) was 2n = 78,XX. Regarding all results of this investigation the diagnose was XX-male. The development of this sexual disorder is discussed. The surgical removal of gonads and uterus and the excision of the enlarged clitoris is described.
authors.affiliation: Klinik für Geburtshilfe, Gynäkologie und Andrologie der Gross- und Kleintiere mit Tierärztlicher Ambulanz.
authors.forename: I
authors.initials: I
authors.lastname: Tammer
authors.forename: A
authors.initials: A
authors.lastname: Herzog
authors.forename: H
authors.initials: H
authors.lastname: Bostedt
mesh_terms: D000818:Animals; D002987:Clitoris / Q000473:pathology / Q000601:surgery; D012734:Disorders of Sex Development / Q000601:surgery / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology; D004285:Dogs; D005260:Female; D008297:Male; D010413:Penis / Q000473:pathology; D012741:Sexual Maturation; D014599:Uterus / Q000473:pathology / Q000601:surgery; D014621:Vagina / Q000473:pathology; D014960:X Chromosome
vernacular_title: Beitrag zur Störung der Sexualentwicklung beim Hund.