A compact respiratory-triggering device for routine microimaging of laboratory mice.
A partial-body plethysmograph was developed for measuring the respiratory flow of anesthetized mice during routine microimaging experiments performed in the close confines of an 89-mm-diameter, vertical-bore magnet. Respiratory flow patterns were used for synchronizing conventional T2-weighted spin-echo imaging with the respiratory cycle, thereby, significantly reducing motion-induced artifacts and increasing observed liver lesion contrast.
Minard
K R
KR
Pacific Northwest National Laboratory, Richland, WA 99352, USA. kr_minard@pnl.gov
Wind
R A
RA
Phelps
R L
RL
D000818:Animals; D016477:Artifacts; D004867:Equipment Design; D008099:Liver / Q000473:pathology*; D008114:Liver Neoplasms, Experimental / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation; D008297:Male; D051379:Mice; D010991:Plethysmography / Q000295:instrumentation*; D012119:Respiration