Isolation of a polymorphic CA repeat sequence at the human progesterone receptor (PGR) locus.
We isolated a polymorphic dinucleotide (CA) repeat sequence from a genomic clone containing the human progesterone receptor (PGR) gene. This polymorphism will be a useful marker in the genetic study of disorders affecting female endocrine systems, such as progesterone resistance and breast, uterine, and ovarian cancers.
Tsukamoto
K
K
Department of Molecular Biology, Nippon Medical School, Kawasaki, Japan.
Watanabe
I
I
Shiba
T
T
Emi
M
M
D000483:Alleles; D002880:Chromosomes, Human, Pair 11; D018900:Dinucleotide Repeats; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011980:Receptors, Progesterone / Q000235:genetics*
D005819:Genetic Markers; D011980:Receptors, Progesterone