Endothelium-dependent flow-mediated vasodilation in coronary and brachial arteries in suspected coronary artery disease.
Previous studies showed a weak correlation between endothelial function of the coronary arteries as assessed by acetylcholine and brachial artery vasomotion during reactive hyperemia. When the same stimulus was used, we obtained a strong correlation between flow-mediated dilation in the coronary and brachial arteries (r=0.78, p <0.001), so that noninvasive assessment of flow-mediated dilation in the brachial artery could be used as a surrogate measure for coronary artery endothelial function.
Takase
B
B
Self Defense Force Central Hospital, Internal Medicine, Tokyo, Japan.
Uehata
A
A
Akima
T
T
Nagai
T
T
Nishioka
T
T
Hamabe
A
A
Satomura
K
K
Ohsuzu
F
F
Kurita
A
A
D000328:Adult; D000368:Aged; D001916:Brachial Artery / Q000503:physiopathology*; D003327:Coronary Disease / Q000503:physiopathology*; D003331:Coronary Vessels / Q000503:physiopathology*; D004730:Endothelium, Vascular / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014664:Vasodilation