title: Novel 1,3-disubstituted-5,10-dihydro-5,10-dioxo-1H-benzo[g] isochromene-3 carboxamides as potent antitumor agents.
abstract: Novel antitumor 5,10-dihydro-5,10-dioxo-1H- benzo[g]isochromene-3-carboxamides were discovered.
authors.affiliation: BioChem Therapeutic Inc., Laval, Québec, Canada.
authors.forename: W
authors.initials: W
authors.lastname: Wang
authors.forename: T
authors.initials: T
authors.lastname: Li
authors.forename: R
authors.initials: R
authors.lastname: Milburn
authors.forename: J
authors.initials: J
authors.lastname: Yates
authors.forename: E
authors.initials: E
authors.lastname: Hinnant
authors.forename: M J
authors.initials: MJ
authors.lastname: Luzzio
authors.forename: S A
authors.initials: SA
authors.lastname: Noble
authors.forename: G
authors.initials: G
authors.lastname: Attardo
mesh_terms: D000577:Amides / Q000737:chemistry / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D014407:Tumor Cells, Cultured
chemical_list: D000577:Amides; D000970:Antineoplastic Agents