Dermatomyositis associated with fallopian tube carcinoma.
Dermatomyositis (DM) is an idiopathic inflammatory myopathy associated with characteristic cutaneous and extracutaneous manifestations, including malignancy. Primary fallopian tube carcinoma (FTC) is the least common site of origin for a malignant neoplasm of the female genital tract. This report describes the first documented case of DM and concurrent FTC in the United States. A 62-year-old woman presented with DM and was subsequently found to have FTC. During her clinical course, she had improvement in strength and function with treatment of the underlying FTC, which also correlated with lower creatinine phosphokinase levels. An association between DM and FTC may exist because of significant functional strength improvements after tumor removal and chemotherapy.
Boudalha
B J
BJ
Department of Physical Medicine and Rehabilitation, Michigan State University/College of Osteopathic Medicine, East Lansing 48824, USA.
Gulick
P
P
Wieting
J M
JM
Andary
M T
MT
Fankhauser
M J
MJ
D000203:Activities of Daily Living; D000230:Adenocarcinoma / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018394:CA-125 Antigen / Q000097:blood; D003131:Combined Modality Therapy; D003402:Creatine Kinase / Q000097:blood; D003882:Dermatomyositis / Q000175:diagnosis / Q000188:drug therapy / Q000201:enzymology / Q000209:etiology*; D005185:Fallopian Tube Neoplasms / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009048:Motor Skills; D010052:Ovariectomy
D000893:Anti-Inflammatory Agents; D018394:CA-125 Antigen; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase; D008775:Methylprednisolone