Localization of lamins in mammalian spermatozoa.
Little information is available concerning lamins in the nucleus of germinal cells. In this paper we briefly describe and compare the organization of A- and B-type lamins in several mammalian spermatozoa. Nuclear lamin B is localized primarily in the postacrosomal sheath of human, bull and rabbit spermatozoa; lamin A/C is a major component of the equatorial segment in most of mammalian sperm, with the exception of rodents. In mouse sperm, devoid of equatorial segment, only lamin B appears to be expressed. The same happens in human pathological spermatozoa in which the equatorial segment is altered or absent.
Goldman
R D
RD
Department of Cellular and Molecular Biology, Northwestern University Medical School, Chicago, IL, USA.
Baccetti
B
B
Collodel
G
G
Gambera
L
L
Moretti
E
E
Piomboni
P
P
D000818:Animals; D006801:Humans; D034904:Lamin Type A; D034921:Lamin Type B; D034882:Lamins; D008297:Male; D051379:Mice; D008854:Microscopy, Electron; D009687:Nuclear Proteins / Q000648:ultrastructure*; D011817:Rabbits; D013094:Spermatozoa / Q000648:ultrastructure*
D034904:Lamin Type A; D034921:Lamin Type B; D034882:Lamins; D009687:Nuclear Proteins