title: [Lack of adherence to the guidelines on the use of fresh frozen plasma].
abstract: OBJECTIVE
  Evaluation of transfusion practice with regard to the guidelines for fresh frozen plasma.
  
  
  METHODS
  Prospective.
  
  
  METHODS
  Academic Medical Centre, department of internal medicine, Amsterdam, the Netherlands.
  
  
  METHODS
  During 4 weeks in April-May 1996 the indication of every request for fresh frozen plasma was established by an inquiry by telephone and compared with the indications defined by the National organization for quality assurance in hospitals (CBO). To objectivate the stated indication it was checked whether laboratory tests had been performed (prothrombin time (PTT) and activated partial thromboplastin time (APTT), and if so, what the results were. Moreover, the numbers of transfused units of red cells, platelets and fresh frozen plasma in the first 24 hours were checked.
  
  
  RESULTS
  During the study period there were 195 requests for 844 units of plasma. 613 units were transfused in 100 patients. If the CBO guidelines were applied strictly, the proportions of plasma units inappropriately requested and inappropriately administered were 53% and 47% respectively (in 32 patients). If the CBO indications were applied less strictly, still 25% of the units were inappropriately requested and 18% inappropriately administered (in 23 patients).
  
  
  CONCLUSIONS
  The guidelines were observed only moderately. Better compliance is important for medical, logistic and financial reasons.
authors.affiliation: Afd. Inwendige Geneeskunde, Academisch Medisch Centrum, Amsterdam.
authors.forename: D
authors.initials: D
authors.lastname: Venema
authors.forename: M
authors.initials: M
authors.lastname: Schut
authors.forename: M H
authors.initials: MH
authors.lastname: van Oers
mesh_terms: D000046:Academic Medical Centers / Q000592:standards; D001803:Blood Transfusion / Q000592:standards* / Q000706:statistics & numerical data; D003625:Data Collection / Q000379:methods; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006801:Humans; D009426:Netherlands; D017410:Practice Guidelines as Topic / Q000592:standards*; D010818:Practice Patterns, Physicians' / Q000592:standards; D011446:Prospective Studies; D011785:Quality Assurance, Health Care; D014600:Utilization Review / Q000706:statistics & numerical data
vernacular_title: Richtlijnen voor het gebruik van vers bevroren plasma suboptimaal nageleefd.