title: Nitroglycosylated meso-arylporphyrins as photoinhibitors of gram positive bacteria.
abstract: Novel porphyrins bearing nitro groups and glucosyl moieties were synthesized. The antibacterial activity of these compounds on Escherichia coli and Staphylococcus aureus is described. Results reveal that their photocytotoxicity is markedly dependent on the nature, the number and the linking position of the glycosyl moieties and nitro groups controlling their amphiphilic characters.
authors.affiliation: Université de Limoges, Laboratoire de Chimie des Substances Naturelles, Limoges.
authors.forename: V
authors.initials: V
authors.lastname: Sol
authors.forename: P
authors.initials: P
authors.lastname: Branland
authors.forename: R
authors.initials: R
authors.lastname: Granet
authors.forename: C
authors.initials: C
authors.lastname: Kaldapa
authors.forename: B
authors.initials: B
authors.lastname: Verneuil
authors.forename: P
authors.initials: P
authors.lastname: Krausz
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects*; D006031:Glycosylation; D010778:Photochemotherapy; D011166:Porphyrins / Q000138:chemical synthesis* / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D011166:Porphyrins