title: Assessment of trans-fatty acid intake with a food frequency questionnaire and validation with adipose tissue levels of trans-fatty acids.
abstract: Past studies of the association of trans-fatty acid intake with coronary heart disease have been hindered by the lack of a database on the trans-fatty acid content of various foods. The authors used new data from the US Department of Agriculture to estimate trans-fatty acid intake using a self-administered food frequency questionnaire (FFQ), and they assessed the validity of the FFQ by comparing the dietary estimates with trans-fatty acid concentrations in adipose tissue. The 1996 study included 27 women and 24 men aged 51-78 years. The mean consumption of total trans-fatty acids estimated from the FFQ was 2.24 g per day and 5% of total dietary fat. The mean concentration of total trans-fatty acids in buttock adipose tissue was 4.7% of total fatty acids. Pearson correlations between total dietary intake of trans-fatty acids and total trans-fatty acid levels in adipose tissue were 0.67 (95% confidence interval (CI) 0.36-0.84) among men and 0.58 (95% CI 0.26-0.79) among women. After adjustment for energy intake, age, and body mass index, the correlation coefficients were 0.76 (95% CI 0.51-0.89) among men and 0.52 (95% CI 0.17-0.75) among women. The FFQ validated in this study is an important new tool for assessing usual intake of trans-fatty acids.
authors.affiliation: Department of Medicine, University of Washington School of Medicine, Seattle, USA.
authors.forename: R N
authors.initials: RN
authors.lastname: Lemaitre
authors.forename: I B
authors.initials: IB
authors.lastname: King
authors.forename: R E
authors.initials: RE
authors.lastname: Patterson
authors.forename: B M
authors.initials: BM
authors.lastname: Psaty
authors.forename: M
authors.initials: M
authors.lastname: Kestin
authors.forename: S R
authors.initials: SR
authors.lastname: Heckbert
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry*; D000368:Aged; D003625:Data Collection; D002149:Energy Intake; D005229:Fatty Acids, Monounsaturated / Q000008:administration & dosage* / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D015203:Reproducibility of Results
chemical_list: D005229:Fatty Acids, Monounsaturated