title: A child with a t(11;19)(q14-21;p12) in a pulmonary mucoepidermoid carcinoma.
abstract: We report on a mucoepidermoid carcinoma (MEC) of the lung in a 6-year-old girl with a t(11;19)(q14-21;p12) as the sole karyotypic abnormality. An apparently identical t(11;19) has been reported previously in a MEC originating from the major and minor salivary glands. Our findings indicate that the t(11;19) is intimately associated with the mucoepidermoid phenotype and may be used as a diagnostic marker for this tumour type.
authors.affiliation: Department of Pathology, Göteborg University, Sahlgrenska University Hospital, Sweden.
authors.forename: G
authors.initials: G
authors.lastname: Stenman
authors.forename: V
authors.initials: V
authors.lastname: Petursdottir
authors.forename: G
authors.initials: G
authors.lastname: Mellgren
authors.forename: J
authors.initials: J
authors.lastname: Mark
mesh_terms: D014408:Biomarkers, Tumor; D018277:Carcinoma, Mucoepidermoid / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D002648:Child; D002880:Chromosomes, Human, Pair 11; D002888:Chromosomes, Human, Pair 19; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007621:Karyotyping; D008175:Lung Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D014178:Translocation, Genetic
chemical_list: D014408:Biomarkers, Tumor