title: [Therapeutic plasmapheresis and alpha-tocopherol in patients with coronary heart disease].
abstract: 46 patients with coronary heart disease with hypercholesterolemia were exposed to therapeutic plasmapheresis (TP) in combination with alpha-tocopherol treatment (AT). The results of 3-month follow-up with assessment of the clinical status, lipid spectrum, lipid peroxidation, concentration of ceruloplasmin indicated high hypolipidemic effectiveness of TP 2-3 weeks after the treatment as shown by inhibition of lipid peroxidation and antioxidant system. The addition of AT prolonged the hypolipidemic effect of TP, promoted optimization of plasma antioxidant potential (a rise in HDL, stabilization of ceruloplasmin levels).
authors.forename: I V
authors.initials: IV
authors.lastname: Logacheva
authors.forename: L A
authors.initials: LA
authors.lastname: Leshchinskiĭ
authors.forename: I I
authors.initials: II
authors.lastname: Odnopozov
authors.forename: N G
authors.initials: NG
authors.lastname: Chernysheva
mesh_terms: D000975:Antioxidants / Q000627:therapeutic use*; D002570:Ceruloplasmin / Q000378:metabolism; D008076:Cholesterol, HDL / Q000097:blood; D003327:Coronary Disease / Q000097:blood / Q000150:complications / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000150:complications / Q000628:therapy; D015227:Lipid Peroxidation; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis; D024505:Tocopherols; D016896:Treatment Outcome; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000627:therapeutic use; D024502:alpha-Tocopherol / Q000031:analogs & derivatives*
chemical_list: D000975:Antioxidants; D008076:Cholesterol, HDL; D008055:Lipids; D014810:Vitamin E; D002570:Ceruloplasmin; D024502:alpha-Tocopherol; D024505:Tocopherols
vernacular_title: Lechebnoe primenenie plazmafereza i alpha-tokoferola u bol'nykh ishemicheskoĭ bolezn'iu serdtsa.