title: Chronotropic response, safety, and accuracy of dobutamine stress echocardiography in patients with atrial fibrillation and known or suspected coronary artery disease.
abstract: Ninety-two consecutive patients with atrial fibrillation (AF) who underwent dobutamine stress echocardiography were compared with a control group of patients in sinus rhythm matched for age, sex, and resting heart rate. Patients with AF had an increased chronotropic response to dobutamine, but there were no adverse effects and no evidence that the lower doses of dobutamine typically given to patients with AF were insufficient to induce ischemia.
authors.affiliation: Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.
authors.forename: T J
authors.initials: TJ
authors.lastname: Hobday
authors.forename: P A
authors.initials: PA
authors.lastname: Pellikka
authors.forename: C H
authors.initials: CH
authors.lastname: Attenhofer Jost
authors.forename: J K
authors.initials: JK
authors.lastname: Oh
authors.forename: F A
authors.initials: FA
authors.lastname: Miller
authors.forename: J B
authors.initials: JB
authors.lastname: Seward
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000368:Aged; D001281:Atrial Fibrillation / Q000503:physiopathology*; D002316:Cardiotonic Agents; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D004280:Dobutamine; D004452:Echocardiography; D005080:Exercise Test; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male
chemical_list: D000319:Adrenergic beta-Antagonists; D002316:Cardiotonic Agents; D004280:Dobutamine