title: An improved method for coronary sinus blood flow monitoring by intravascular Doppler technique.
abstract: In order to obtain accurate measurements of coronary sinus blood flow (CSBF), a new catheter (7 French) with a radiopaque, flexible, and basket-shaped tip was developed for guiding a standard 3 Fr Doppler catheter in the coronary sinus (CS) in man. The radiopaque "basket" tip of the catheter allows the operator to stabilize the position of the Doppler transducer in the center of the CS and to accurately measure the CS internal diameter radiologically. CSBF was calculated as the product of CS cross-sectional area by mean CSBF velocity. Doppler-derived CSBF values at rest and during handgrip were compared with those obtained by the local thermodilution technique in 16 patients undergoing diagnostic coronary angiography. During handgrip, mean CSBF increased from 154+/-23 (rest) to 299+/-34 mL/min by the Doppler method and from 148+/-22 to 288+/-32 mL/min by the thermodilution technique. A good correlation (r = 0.86) between the CSBF values with the two techniques was observed. The authors conclude that the intravascular Doppler technique associated with the use of the basket guide catheter provides an accurate and simple tool for monitoring CSBF in patients.
authors.affiliation: Istituto di Clinica Medica Generale e Terapia Medica, Università di Milano, Ospedale Maggiore di Milano, Milan, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Vandoni
authors.forename: R
authors.initials: R
authors.lastname: Perondi
authors.forename: A
authors.initials: A
authors.lastname: Saino
authors.forename: G
authors.initials: G
authors.lastname: Pomidossi
authors.forename: M
authors.initials: M
authors.lastname: Ciulla
authors.forename: R
authors.initials: R
authors.lastname: Paliotti
authors.forename: G
authors.initials: G
authors.lastname: Tortora
authors.forename: P
authors.initials: P
authors.lastname: Valentini
authors.forename: F
authors.initials: F
authors.lastname: Magrini
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D002404:Catheterization / Q000295:instrumentation; D002637:Chest Pain / Q000000981:diagnostic imaging; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000502:physiology; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D013815:Thermodilution; D018608:Ultrasonography, Doppler / Q000379:methods*; D018084:Ultrasonography, Interventional / Q000379:methods*