Functional molecules based on polyazometals. (1). Artificial metalloproteinases prepared by conjugation of polyazometals with poly(allylamine).
Polyazometals (PAMs) conjugated with poly(allylamine) manifested high catalytic activity in the hydrolytic cleavage of bovine serum albumin. Based on cleavage sites, the mechanism for the PAM-catalyzed peptide hydrolysis is suggested.
Suh
J
J
Department of Chemistry and Center for Molecular Catalysis, Seoul National University, Korea.
Moon
S J
SJ
D000499:Allylamine / Q000031:analogs & derivatives* / Q000737:chemistry; D001391:Azo Compounds / Q000737:chemistry*; D001665:Binding Sites; D002384:Catalysis; D007700:Kinetics; D008666:Metalloendopeptidases / Q000138:chemical synthesis* / Q000378:metabolism*; D009942:Organometallic Compounds / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D012710:Serum Albumin, Bovine / Q000378:metabolism
D001391:Azo Compounds; D009942:Organometallic Compounds; D011108:Polymers; D012710:Serum Albumin, Bovine; D000499:Allylamine; D008666:Metalloendopeptidases