title: The synthesis of a new type of anthracene DNA intercalator.
abstract: A new type of DNA intercalator based on anthracene 3 was synthesized. Preliminary binding studies show high affinity of this probe to CT-DNA. Higher binding constant of this compound (4.0 x 10(4) M-1) as compared with that known for 9-aminomethylanthracene, is caused presumably by enhanced electrostatic interaction.
authors.affiliation: Institute of Organic Chemistry, Polish Academy of Sciences, Warszawa. RYSZA@ICHF.EDU.PL
authors.forename: R
authors.initials: R
authors.lastname: Ostaszewski
authors.forename: E
authors.initials: E
authors.lastname: Wilczyńska
authors.forename: M
authors.initials: M
authors.lastname: Wolszczak
mesh_terms: D004247:DNA / Q000378:metabolism; D007364:Intercalating Agents / Q000138:chemical synthesis* / Q000378:metabolism
chemical_list: D007364:Intercalating Agents; D004247:DNA