title: [Melanoma in pregnancy].
abstract: The incidence of pregnancy complicated by melanoma of the skin, calculated from data of the Netherlands Cancer Registry, is 1 per 10,000 pregnancies. The prognosis of a melanoma is not affected by prior or subsequent pregnancy. A melanoma diagnosed during pregnancy does appear to have a more unfavourable prognosis, due not to a less favourable clinical course, but to a delay in diagnosing melanoma during pregnancy and (or) a less favourable site. When a pregnancy is complicated by malignancy, in case of a melanoma there is a higher risk of placental metastasis compared with other malignancies. In nearly 50% of the cases reported in literature of placental metastasis there was foetal involvement.
authors.affiliation: Academisch Ziekenhuis, afd. Gynaecologie en Obstetrie, Nijmegen.
authors.forename: A C
authors.initials: AC
authors.lastname: de Wit
authors.forename: J M
authors.initials: JM
authors.lastname: Merkus
mesh_terms: D000328:Adult; D017677:Age Distribution; D005260:Female; D005315:Fetal Diseases / Q000401:mortality; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008545:Melanoma / Q000453:epidemiology*; D009426:Netherlands / Q000453:epidemiology; D010298:Parity; D010922:Placenta Diseases / Q000401:mortality; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000453:epidemiology*; D011297:Prenatal Exposure Delayed Effects; D011379:Prognosis; D012008:Recurrence; D012878:Skin Neoplasms / Q000453:epidemiology*; D015996:Survival Rate
vernacular_title: Melanoom en zwangerschap.