title: [Electromyogram (EMG) and muscle biopsy in patients with chronic spinal muscular atrophy].
abstract: The clinicopathological changes were investigated by electromyogram (EMG) and muscle biopsy in 30 cases of chronic spinal muscular atrophy. The results showed that the denervating changes were demonstrated in EMG in all patients but two. The light microscope discovered manifestation of neurogenic atrophy, and the electron microscope revealed a reduction of myofibrils, thickening and wavy appearance of Z-lines and dilation of mitochondria and endoplasmic reticula.
authors.affiliation: Department of Neurological, Xiangya Hospital, Hunan Medical University, Changsha.
authors.forename: Y
authors.initials: Y
authors.lastname: Yang
authors.forename: B
authors.initials: B
authors.lastname: Xiao
authors.forename: G
authors.initials: G
authors.lastname: Xie
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology*; D009134:Muscular Atrophy, Spinal / Q000473:pathology* / Q000503:physiopathology