title: Pogosta disease: clinical observations during an outbreak in the province of North Karelia, Finland.
abstract: OBJECTIVE
  To characterize the clinical picture of Pogosta disease.
  
  
  METHODS
  The data of 73 patients who had had Pogosta disease in 1981 and who then had been seen by a local physician in North Karelia were analysed.
  
  
  RESULTS
  The main manifestations were fever (23%), rash (88%) and joint symptoms (93%). The joint symptoms in some patients lasted for several months and were severe enough to cause immobilization. The clinical picture was identical in those patients who had a definite serological diagnosis and those who did not have a detectable antibody response.
  
  
  CONCLUSIONS
  The symptoms of Sindbis virus-induced Pogosta discase consist of fever, rash and joint symptoms, whic may be severe and prolonged.
authors.affiliation: Department of Medicine, Turku University, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Turunen
authors.forename: P
authors.initials: P
authors.lastname: Kuusisto
authors.forename: P E
authors.initials: PE
authors.lastname: Uggeldahl
authors.forename: A
authors.initials: A
authors.lastname: Toivanen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018354:Alphavirus Infections / Q000503:physiopathology*; D016918:Arthritis, Reactive / Q000175:diagnosis / Q000473:pathology / Q000821:virology*; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005387:Finland; D006801:Humans; D007592:Joint Diseases / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010146:Pain; D012720:Severity of Illness Index; D012845:Sindbis Virus / Q000472:pathogenicity*