title: Acute hyponatremia in the perioperative period: insights into its pathophysiology and recommendations for management.
abstract: Our purpose is to review the topic of acute postoperative hyponatremia by focusing on pertinent aspects of the physiology of water and solute excretion. Four areas will be highlighted: an examination of the source of addition of electrolyte-free water, an exploration of the basis for the very large natriuresis that occurs during cerebral salt wasting following neurosurgery, possible reasons to explain why acute postoperative hyponatremia may pose a greater risk for young women [Ayus and Arieff 1996, Ayus et al. 1992, Arieff 1986, Wijdick et al. 1991], and issues related to treatment of acute hyponatremia.
authors.affiliation: Department of Pediatrics, University of Alberta, Edmonton, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Gowrishankar
authors.forename: S H
authors.initials: SH
authors.lastname: Lin
authors.forename: J P
authors.initials: JP
authors.lastname: Mallie
authors.forename: M S
authors.initials: MS
authors.lastname: Oh
authors.forename: M L
authors.initials: ML
authors.lastname: Halperin
mesh_terms: D000208:Acute Disease; D001921:Brain / Q000378:metabolism; D006801:Humans; D007010:Hyponatremia / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D009318:Natriuresis; D011183:Postoperative Complications; D012964:Sodium / Q000378:metabolism; D014882:Water-Electrolyte Balance
chemical_list: D012964:Sodium