title: [Writer's cramp treated with botulinum injections].
abstract: OBJECTIVE
  To evaluate the first clinical experience with local botulinum toxin A (BTA) injections in patients with writer's cramp.
  
  
  METHODS
  Descriptive.
  
  
  METHODS
  Academic Medical Centre, Amsterdam, the Netherlands.
  
  
  METHODS
  In May 1993-January 1996 ten patients with writer's cramp were treated with BTA (Dysport). Age of the patients varied from 28 to 68 years, the duration of complaints from 1 to 29 years. Muscles for injections were selected by observation, sometimes combined with electromyography. BTA was administered under electromyographic guidance.
  
  
  RESULTS
  The amount of BTA administered per treatment session ranged from 15 to 400 IU. In three patients the BTA-induced weakness necessary to reach a beneficial effect on writing was unacceptable. In seven patients the response was satisfactory or good and lasted 2 to 15 months (mean: 3.5 months).
  
  
  CONCLUSIONS
  The results confirm the efficacy of BTA in writer's cramp.
authors.affiliation: Academisch Medisch Centrum, Amsterdam.
authors.forename: J H
authors.initials: JH
authors.lastname: Koelman
authors.forename: M A
authors.initials: MA
authors.lastname: Struys
authors.forename: B W
authors.initials: BW
authors.lastname: Ongerboer de Visser
authors.forename: J D
authors.initials: JD
authors.lastname: Speelman
mesh_terms: D000328:Adult; D000368:Aged; D019274:Botulinum Toxins, Type A / Q000009:adverse effects / Q000627:therapeutic use*; D004576:Electromyography / Q000379:methods; D005260:Female; D006225:Hand; D006236:Handwriting; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D009120:Muscle Cramp / Q000188:drug therapy*; D018908:Muscle Weakness / Q000139:chemically induced; D009465:Neuromuscular Agents / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A
vernacular_title: Schrijfkramp behandeld met botuline-injecties.