Myotonia associated with hyperadrenocorticism in two dogs.
Two dogs developed a disabling gait abnormality characterised by stiffness. The abnormality was consistent with a diagnosis of myotonia secondary to hyperadrenocorticism. The first dog had iatrogenic hyperadrenocorticism, and its signs improved substantially after corticosteroid administration was gradually withdrawn. The second had pituitary-dependent hyperadrenocorticism, but myotonic signs progressed despite effective mitotane therapy. Procainamide administration reduced the myotonic stiffness in the second case.
Swinney
G R
GR
Department of Veterinary Clinical Sciences, University of Sydney, New South Wales.
Foster
S F
SF
Church
D B
DB
Malik
R
R
D000308:Adrenocortical Hyperfunction / Q000139:chemically induced / Q000150:complications / Q000662:veterinary*; D000818:Animals; D001623:Betamethasone / Q000009:adverse effects; D004283:Dog Diseases / Q000209:etiology*; D004285:Dogs; D004576:Electromyography / Q000662:veterinary; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects; D007049:Iatrogenic Disease / Q000662:veterinary; D008297:Male; D009222:Myotonia / Q000209:etiology / Q000662:veterinary*
D005938:Glucocorticoids; D001623:Betamethasone