title: Regulation of cell adhesion, a central mechanism in the anticancer action of essential fatty acids (review).
abstract: Certain members of essential fatty acids (EFAs) are known to have anticancer functions. It has been established in recent years that some of these anticancer actions are via the effects of these fatty acids on the adhesive properties of cancer cells, including cell-cell and cell-matrix adhesions. These discoveries have implicated EFAs as a group of novel agents, able to regulate adhesive function of cancer cells and thus bearing clinical importance.
authors.affiliation: Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Cardiff, UK.
authors.forename: W G
authors.initials: WG
authors.lastname: Jiang
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002448:Cell Adhesion / Q000187:drug effects*; D005228:Fatty Acids, Essential / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D005228:Fatty Acids, Essential