Prediction of migraine attacks using a slow cortical potential, the contingent negative variation.
Amplitudes of contingent negative variation (CNV) as a slow cortical potential in migraine patients were recorded before and after migraine attacks. The level of CNV amplitudes, especially of the early component, showed a trend in rise of negativity 1 day before the attack, whereas amplitudes were normal for 2-3 days following an attack. In most cases the attack occurred when the CNV amplitude showed maximum negativity. We conclude that migraine-susceptible days are indicated by a high CNV amplitude the day before the attack.
Kropp
P
P
Institute of Medical Psychology, Center of Nervous Diseases, Kiel, Germany. kropp@med-psych.uni-kiel.de
Gerber
W D
WD
D000328:Adult; D002540:Cerebral Cortex / Q000503:physiopathology*; D003265:Contingent Negative Variation / Q000502:physiology*; D004198:Disease Susceptibility / Q000503:physiopathology; D005544:Forecasting; D006801:Humans; D008881:Migraine Disorders / Q000503:physiopathology*; D011930:Reaction Time / Q000502:physiology