title: Infection with the human immunodeficiency virus type 2: epidemiology and transmission (Review).
abstract: Human immunodeficiency virus type 2 (HIV-2) is known to be one of the agents that causes acquired immunodeficiency syndrome (AIDS). It has been present in West Africa since the 1960s and is currently epidemic there. Compared with human immunodeficiency virus type 1 (HIV-1), HIV-2 is genomically different. Furthermore, it is less prevalent worldwide than HIV-1. In West Africa, seropositive rates of HIV-2 are higher in urban versus rural communities, however, there are no gender differences. Sexual contact and vertical transmission are known modes of infectivity, though HIV-2 is less contagious than HIV-1.
authors.affiliation: Developmental Therapeutics Department, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Q
authors.initials: Q
authors.lastname: Li
authors.forename: B
authors.initials: B
authors.lastname: Tsang
authors.forename: L
authors.initials: L
authors.lastname: Ding
authors.forename: W
authors.initials: W
authors.lastname: Ji-Hong
mesh_terms: D000349:Africa; D000818:Animals; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000635:transmission; D015528:HIV Seroprevalence; D015498:HIV-2 / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D011247:Pregnancy