title: The accuracy of abdominal ultrasound in the assessment of bowel disorders.
abstract: BACKGROUND
  Little is known about the sensitivity, specificity, and predictive values of transabdominal ultrasonographic (US) findings in a teaching hospital setting.
  
  
  METHODS
  We carried out a prospective study including 227 patients with symptoms suggestive of inflammatory bowel disorder. The Picker 9200 CS equipment (5-mHz curved-array probe) was used to obtain bowel images. Gastrointestinal endoscopy, enteroclysis, bowel enema, computed tomography scan, or bowel surgery was used as reference.
  
  
  RESULTS
  Of 227 patients, 168 had pathologic findings of the bowel as final diagnosis. The overall sensitivity of US was 76%, whereas the positive predictive value was 98%. Overall specificity was 95%. The negative predictive value for bowel disorders was only 58%, since US missed pathologic findings in 48 patients. Subgroup analysis showed a sensitivity of 84% for Crohn's disease, 66% for ulcerative colitis, 46% for bowel tumors, and 60% for diverticulitis. Topographic comparisons showed that US detected inflammatory bowel-wall alterations preferentially in the terminal ileum and colon, whereas abnormalities in the duodenum, jejunum, and rectum were frequently missed (sensitivity, 10%-20%).
  
  
  CONCLUSIONS
  Positive US findings are useful for the diagnosis of bowel processes. US is highly predictive albeit not disease-specific. Negative US examinations, however, do not exclude pathologic bowel processes. A topographic location of pathologic US findings is mostly confined to the colon.
authors.affiliation: Dept. of Internal Medicine I, Institute of Radiology, University of Regensburg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Hollerbach
authors.forename: A
authors.initials: A
authors.lastname: Geissler
authors.forename: H
authors.initials: H
authors.lastname: Schiegl
authors.forename: F
authors.initials: F
authors.lastname: Kullmann
authors.forename: G
authors.initials: G
authors.lastname: Lock
authors.forename: J
authors.initials: J
authors.lastname: Schmidt
authors.forename: J
authors.initials: J
authors.lastname: Schlegel
authors.forename: J
authors.initials: J
authors.lastname: Schoelmerich
authors.forename: T
authors.initials: T
authors.lastname: Andus
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000453:epidemiology; D007422:Intestines / Q000000981:diagnostic imaging; D008297:Male; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014463:Ultrasonography