title: [The role of nuclear magnetic resonance monitoring in early clinical-instrumental diagnosis of multiple sclerosis].
abstract: Nucleo-magnetic resonance tomography (NMRT) facilitated considerably early diagnosis of multiple sclerosis. Yet, there appeared data indicating the existence of NMRT negative forms. These were found in 15 patients of 82 ones examined using NMRT only which failed to defect foci of demyelinization in spite of a clear-cut clinical picture. NMRT monitoring during 3 years (from 2 to 5 NMRT investigations) permitted to visualize the foci of demyelinization located primarily in the periventricular cerebral region. The conclusion was made that a presence of clear clinical symptoms as well as a remitting character of the pathologic process confirmed by visualization of multiple foci of CNS demyelinization by means of NMRT monitoring, gave full chance for a reliable diagnosis of multiple sclerosis. A lack of such confirmation may be explained by the fact, that clinical debut of the disease reflected only the phase of multiple sclerosis and forestalled forming of a focal demyelinizating process, pathognomonic for this disease.
authors.forename: S K
authors.initials: SK
authors.lastname: Evtushenko
authors.forename: I N
authors.initials: IN
authors.lastname: Derevianko
mesh_terms: D000293:Adolescent; D000328:Adult; D003711:Demyelinating Diseases / Q000175:diagnosis; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis*; D013997:Time Factors
vernacular_title: Rol' iaderno-magnitno-rezonansnogo monitorirovaniia v ranneĭ kliniko- instrumental'noĭ diagnostike rasseiannogo skleroza.