Synthesis of diacylamines and the preparation of alpha-amino-acylureas, a new type of alpha-amino acid derivatives.
Sixteen new and one known unsymmetrical open-chain diacylamines were synthesized by sodium methoxide catalyzed acylation of amides with carboxylic esters and acylamino-carboxylic esters, or acylureas with acylamino-carboxylic esters and alpha-amino acid esters.
Weisz
I
I
Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.
Roboz
J
J
Wolf
I
I
Szabo
J
J
Bekesi
J G
JG
D000588:Amines / Q000138:chemical synthesis*; D000596:Amino Acids / Q000138:chemical synthesis*; D000927:Anticonvulsants / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000494:pharmacology
D000588:Amines; D000596:Amino Acids; D000927:Anticonvulsants; D000970:Antineoplastic Agents