Edema in the upper airway in patients with obstructive sleep apnea syndrome.
OBJECTIVE
The purpose of this study was to investigate the histologic alterations in the upper airway in patients with obstructive sleep apnea syndrome.


METHODS
Surgical specimens were obtained during non-laser-assisted uvulopalatopharyngoplasty from 5 adult patients (4 male and 1 female) with polysomnographically confirmed obstructive sleep apnea syndrome.


RESULTS
In all of the specimens, interstitial edema was present with mild inflammatory reaction. Fat was not at all prominent.


CONCLUSIONS
It is confirmed histologically that there is edema present in the upper airway in patients with obstructive sleep apnea syndrome. It is uncertain whether this edema is one of the causative mechanisms of the obstruction or a consequence of the syndrome.
Anastassov
G E
GE
Mount Sinai School of Medicine.
Trieger
N
N
D000328:Adult; D000368:Aged; D000402:Airway Obstruction / Q000209:etiology / Q000473:pathology*; D004487:Edema / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010608:Pharyngeal Diseases / Q000150:complications* / Q000473:pathology; D010614:Pharynx / Q000601:surgery; D012891:Sleep Apnea Syndromes / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D014609:Uvula / Q000601:surgery