Inositol monophosphatase in immortalized lymphoblastoid cell lines indicates susceptibility to bipolar disorder and response to lithium therapy.
Shamir
A
A
Ebstein
R P
RP
Nemanov
L
L
Zohar
A
A
Belmaker
R H
RH
Agam
G
G
D000704:Analysis of Variance; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics*; D002461:Cell Line, Transformed; D002898:Chromosomes, Human, Pair 8; D020022:Genetic Predisposition to Disease; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D008214:Lymphocytes / Q000201:enzymology*; D010744:Phosphoric Monoester Hydrolases / Q000235:genetics / Q000378:metabolism*; D011379:Prognosis; D012016:Reference Values
D008094:Lithium; D010744:Phosphoric Monoester Hydrolases; C021822:myo-inositol-1 (or 4)-monophosphatase