Infrared studies of protein-induced perturbation of lipids in lipoproteins and membranes.
The paper reviews the main recent publications concerning infrared (IR) spectroscopy as applied to the study of lipid-protein interactions in model and cell membranes, lipoproteins, and related systems (e.g. lung surfactant). The review focuses mainly on transmission IR. Based on the available data, a number of general conclusions are presented on the perturbations caused by proteins on either the hydrocarbon chains, the polar headgroups or the interface region. Lipid-protein interactions in native cell membranes do not reveal significant differences from what is observed in semisynthetic model systems.
Arrondo
J L
JL
Departamento de Bioquímica, Universidad del País Vasco, Bilbao, Spain.
Goñi
F M
FM
D000818:Animals; D006801:Humans; D008074:Lipoproteins / Q000737:chemistry*; D008563:Membrane Lipids / Q000737:chemistry*; D008565:Membrane Proteins / Q000737:chemistry*; D013055:Spectrophotometry, Infrared
D008074:Lipoproteins; D008563:Membrane Lipids; D008565:Membrane Proteins