[Clinical and experimental study on improving cellular immunological function of uterine myoma patients by xiaoliu tablet].
OBJECTIVE
To explore the effect of Xiaoliu Tablet (XLT) in treating uterine myoma (UM) and the relationship between effect and the cellular immunological function of the UM patients.


METHODS
Seventy-one UM patients by treatment with XLT was observed. The activities of natural killer (NK) cells of 50 patients and 30 normal women were determined.


RESULTS
There were good effect in reducing the volume of myoma and improving the menses by XLT, especially in patients whose myoma were singly and small. The activity of NK cells of these patients (24.61 +/- 6.04%, n = 50) was significantly different from that of normal women (45.42 +/- 9.05%, n = 30), P < 0.01. There was a notable rise of NK cells of the patients (37.54 +/- 5.01%, n = 39), after the treatment of six months by XLT (P < 0.01).


CONCLUSIONS
Improving the immunological function might be one of the mechanisms of the effect of XLT.
Zhou
J
J
Yueyang Hospital affiliated to Shanghai University of TCM, Shanghai.
Zhu
M
M
Li
Y X
YX
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D000818:Animals; D016516:CD4-CD8 Ratio; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology; D007889:Leiomyoma / Q000188:drug therapy* / Q000276:immunology; D051379:Mice; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000188:drug therapy* / Q000276:immunology
D000276:Adjuvants, Immunologic; D004365:Drugs, Chinese Herbal