Anticytomegalovirus (anti-CMV) immunoglobulin G avidity in identification of pregnant women at risk of transmitting congenital CMV infection.
In this work, we show that the determination of the anticytomegalovirus antibody avidity carried out before week 18 of gestation is a helpful tool to identify women for enrollment in prenatal diagnosis. This procedure can identify all pregnant women who will give birth to an infected newborn.
Lazzarotto
T
T
Department of Clinical and Experimental Medicine, Section of Microbiology, Medical School, University of Bologna, Bologna, Italy.
Spezzacatena
P
P
Varani
S
S
Gabrielli
L
L
Pradelli
P
P
Guerra
B
B
Landini
M P
MP
D000653:Amniotic Fluid / Q000821:virology; D000914:Antibodies, Viral / Q000097:blood*; D000915:Antibody Affinity; D016022:Case-Control Studies; D003587:Cytomegalovirus / Q000276:immunology* / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000150:complications / Q000151:congenital* / Q000635:transmission*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000276:immunology*; D011296:Prenatal Diagnosis; D012307:Risk Factors
D000914:Antibodies, Viral; D007074:Immunoglobulin G