[Delayed evaluation of urea content in bioassays using a chemical stabilizer].
We have studied 126 chemical compounds. Moreover 9-triphenylphosphoniomethyl-phenanthrene chloride has been found to stabilize bioassays and preserve their urea content unchanged for a period of 90-990 days. Due to its use a delayed technique of a quantitative assessment of urea in biological objects has been elaborated characterized by universal novelty. It may be used with the aim of studying metabolic processes in the cosmonauts' body, atomic submarine crews, members of polar, alpine, desert, underwater, space and other expeditions which cannot be accompanied by a biochemical laboratory.
Iarmol'chuk
H M
HM
Bucovina State Medical Academy, Chernivtsi.
D000818:Animals; D001681:Biological Assay; D002648:Child; D005069:Evaluation Studies as Topic; D005079:Excipients / Q000737:chemistry*; D006801:Humans; D010616:Phenanthrenes / Q000737:chemistry*; D051381:Rats; D013997:Time Factors; D014508:Urea / Q000378:metabolism*
C116344:9-triphenylphosphoniomethylphenanthrene chloride; D005079:Excipients; D010616:Phenanthrenes; D014508:Urea
Vidstrochene vyznachennia vmistu sechovyny v biolohichnykh probakh za dopomohoiu khimichnoho stabilizatora.