Metabolites from the sponge-associated bacterium Micrococcus luteus.
In an ongoing survey of the bioactive potential of microorganisms associated with marine invertebrates, the extract of the sponge-associated bacterial strain Micrococcus luteus was found to exhibit potent antimicrobial activity. The previously known synthetic 2,4,4'-trichloro-2'-hydroxydiphenylether was found to be responsible for the antimicrobial activity. The major metabolite isolated was a new acyl-1-(acyl-6'-mannobiosyl)-3-glycerol.
Bultel-Poncé
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Laboratoire de Chimie des Substances Naturelles du Museum National d'Histoire Naturelle, associé au CNRS, 63 rue Buffon, 75005 Paris, France
Debitus
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Berge
JP
Cerceau
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Guyot
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