title: Synchronous testicular seminoma and adrenocortical carcinoma: a case report.
abstract: We report a rare case of synchronous testicular seminoma and adrenocortical carcinoma. A 57-year-old man had a left testicular seminoma (clinical stage IIIB) with metastases to the lung and paraaortic lymph node. A complete response was obtained after 3 courses of chemotherapy with single-agent carboplatin. However, a left adrenal tumor was detected 1 2 months later and demonstrated a tumor volume doubling time of 2.1 months. Chemotherapy with bleomycin, etoposide and cisplatin failed to stop the tumor growth. A laparoscopic adrenalectomy was performed and pathology revealed an adrenocortical carcinoma. The patient has been free of recurrence for 42 months postoperatively.
authors.affiliation: Department of Urology, Faculty of medicine, Kyoto University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Inoue
authors.forename: A
authors.initials: A
authors.lastname: Terai
authors.forename: T
authors.initials: T
authors.lastname: Terachi
authors.forename: T
authors.initials: T
authors.lastname: Souma
authors.forename: O
authors.initials: O
authors.lastname: Yoshida
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D002277:Carcinoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D018239:Seminoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed