title: Novel cytokine release inhibitors. Part II: Steroids.
abstract: Steroidal derivatives as IL-1 beta release inhibitors are discussed.
authors.affiliation: Department of Medicinal Chemistry, Rhône-Poulenc Rorer Central Research, Collegeville, PA 19426, USA.
authors.forename: W
authors.initials: W
authors.lastname: He
authors.forename: F C
authors.initials: FC
authors.lastname: Huang
authors.forename: M
authors.initials: M
authors.lastname: Morytko
authors.forename: N
authors.initials: N
authors.lastname: Jariwala
authors.forename: K T
authors.initials: KT
authors.lastname: Yu
mesh_terms: D000893:Anti-Inflammatory Agents / Q000737:chemistry* / Q000494:pharmacology; D002478:Cells, Cultured; D006801:Humans; D020128:Inhibitory Concentration 50; D007375:Interleukin-1 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D009000:Monocytes / Q000187:drug effects / Q000378:metabolism; D013256:Steroids / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000893:Anti-Inflammatory Agents; D007375:Interleukin-1; D013256:Steroids