title: Functional MRI of the lumbar spine in erect position in a superconducting open-configuration MR system: preliminary results.
abstract: The purpose of this study was to determine the feasibility of obtaining, and findings in, functional MRI of the lumbar spine in an erect position and with flexion and extension. Thirty subjects (including 5 volunteers) were imaged in a sitting position and while performing flexion and extension. The alternations in posterior disk margin, size of neural foramina, and central canal were evaluated. In addition, routine supine imaging was accomplished in 15 of these subjects. The foraminal size and posterior disk margins did not change appreciably from supine to upright position. With extension, there was an increased disk bulge in 27% of disks (40% of those with desiccation). Central canal size (50%) and foraminal size (27%) decreased with extension, especially at levels with disk desiccation. Images obtained with our open-configuration MR unit were diagnostically adequate, although of inferior quality compared with those obtained with a conventional unit. Our preliminary results show the feasibility of obtaining diagnostic images of the erect lumbar spine with flexion and extension. The results are in agreement with those obtained with cadaveric studies. The utility of this method in diagnostic imaging of patients with low back pain remains to be determined.
authors.affiliation: Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA.
authors.forename: A A
authors.initials: AA
authors.lastname: Zamani
authors.forename: T
authors.initials: T
authors.lastname: Moriarty
authors.forename: L
authors.initials: L
authors.lastname: Hsu
authors.forename: C S
authors.initials: CS
authors.lastname: Winalski
authors.forename: J L
authors.initials: JL
authors.lastname: Schaffer
authors.forename: H
authors.initials: H
authors.lastname: Isbister
authors.forename: J F
authors.initials: JF
authors.lastname: Schenck
authors.forename: K W
authors.initials: KW
authors.lastname: Rohling
authors.forename: F
authors.initials: F
authors.lastname: Jolesz
mesh_terms: D000328:Adult; D000368:Aged; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007403:Intervertebral Disc / Q000033:anatomy & histology / Q000502:physiology; D008159:Lumbar Vertebrae / Q000033:anatomy & histology* / Q000502:physiology; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D011187:Posture; D012016:Reference Values; D013115:Spinal Canal / Q000033:anatomy & histology / Q000502:physiology