title: Functionalized 1,3-teraryls as a new class of hepatoprotectants. Part V.
abstract: Functionalized 1,3-teraryls, synthesized through ring transformation of 6-aryl-3-carbomethoxy-4-methylthio-2H-pyran-2-one from arylketone have been screened for their hepatoprotective activity and of them have demonstrated significant protection in animal model.
authors.affiliation: Division of Medicinal Chemistry, Central Drug Research Institute, Lucknow, India.
authors.forename: V J
authors.initials: VJ
authors.lastname: Ram
authors.forename: A
authors.initials: A
authors.lastname: Goel
authors.forename: G K
authors.initials: GK
authors.lastname: Patnaik
mesh_terms: D000818:Animals; D008099:Liver / Q000187:drug effects*; D008107:Liver Diseases / Q000517:prevention & control*; D020011:Protective Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D011753:Pyrones / Q000138:chemical synthesis / Q000494:pharmacology*; D051381:Rats
chemical_list: D020011:Protective Agents; D011753:Pyrones