title: SCOP: a Structural Classification of Proteins database.
abstract: The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of all known proteins structures. The classification is on hierarchical levels: the first two levels, family and superfamily, describe near and far evolutionary relationships; the third, fold, describes geometrical relationships. The distinction between evolutionary relationships and those that arise from the physics and chemistry of proteins is a feature that is unique to this database, so far. The database can be used as a source of data to calibrate sequence search algorithms and for the generation of population statistics on protein structures. The database and its associated files are freely accessible from a number of WWW sites mirrored from URL http://scop. mrc-lmb.cam.ac.uk/scop/
authors.affiliation: Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
authors.forename: T J
authors.initials: TJ
authors.lastname: Hubbard
authors.forename: B
authors.initials: B
authors.lastname: Ailey
authors.forename: S E
authors.initials: SE
authors.lastname: Brenner
authors.forename: A G
authors.initials: AG
authors.lastname: Murzin
authors.forename: C
authors.initials: C
authors.lastname: Chothia
mesh_terms: D000465:Algorithms; D016208:Databases, Factual; D019143:Evolution, Molecular; D016247:Information Storage and Retrieval; D020407:Internet; D011487:Protein Conformation; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry* / Q000145:classification* / Q000235:genetics; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D013223:Statistics as Topic
chemical_list: D011506:Proteins