title: Central retinal vein occlusion associated with cryofibrinogenemia in a young adult--study of skin dynamic capillaroscopy.
abstract: A 26-year-old woman presented with a 2-month history of intermittent dim vision in her right eye and a diagnosis of central retinal vein occlusion (CRVO) was made. Investigations revealed Raynaud's phenomenon and cryofibrinogenemia. Skin capillaroscopy revealed tortuous vessels and decreased capillary blood-cell velocity in the capillaries of her finger nail fold which coincided with the CRVO attack. After treatment with oral aspirin for 3 months, the CRVO subsided, the capillary blood-cell velocity in the nail fold improved, and serum cryofibrinogen was undetectable. The time course of the cryofibrinogenemia and skin capillaroscopic findings correlated well with her ocular presentations. Study of cryofibrinogen should be included in the evaluation of young adults with CRVO.
authors.affiliation: Department of Ophthalmology, School of Medicine, Kaohsiung Medical College, Taiwan.
authors.forename: R K
authors.initials: RK
authors.lastname: Tsai
authors.forename: C H
authors.initials: CH
authors.lastname: Chang
mesh_terms: D000328:Adult; D002196:Capillaries / Q000503:physiopathology; D003450:Cryoglobulins / Q000032:analysis*; D005260:Female; D015241:Fibrinogens, Abnormal / Q000032:analysis*; D006801:Humans; D012170:Retinal Vein Occlusion / Q000503:physiopathology*; D012867:Skin / Q000098:blood supply*
chemical_list: D003450:Cryoglobulins; D015241:Fibrinogens, Abnormal; C041874:cryofibrinogen