title: Hereditary spastic paraplegia with a thin corpus callosum and thalamic involvement in Japan.
abstract: The authors examined two Japanese siblings with a recessive hereditary spastic paraplegia (HSP) with dementia and a thin corpus callosum. Both showed thalamic glucose hypometabolism on PET. Recessive HSP with a thin corpus callosum is a rare disorder, with less than 20 reported patients, that may be a Japanese subtype of HSP.
authors.affiliation: Second Department of Internal Medicine, Nippon Medical School Main Hospital, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ueda
authors.forename: Y
authors.initials: Y
authors.lastname: Katayama
authors.forename: T
authors.initials: T
authors.lastname: Kamiya
authors.forename: M
authors.initials: M
authors.lastname: Mishina
authors.forename: H
authors.initials: H
authors.lastname: Igarashi
authors.forename: S
authors.initials: S
authors.lastname: Okubo
authors.forename: M
authors.initials: M
authors.lastname: Senda
authors.forename: K
authors.initials: K
authors.lastname: Iwabuchi
authors.forename: A
authors.initials: A
authors.lastname: Terashi
mesh_terms: D000328:Adult; D001921:Brain / Q000378:metabolism / Q000473:pathology; D003337:Corpus Callosum / Q000378:metabolism / Q000473:pathology*; D005192:Family Health; D006801:Humans; D007564:Japan; D008297:Male; D009679:Nuclear Family; D015419:Spastic Paraplegia, Hereditary / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D013788:Thalamus / Q000378:metabolism / Q000473:pathology*; D014055:Tomography, Emission-Computed