title: Conservative treatment of lower pole breast cancers by bilateral mammoplasty and radiotherapy.
abstract: OBJECTIVE
  This series analyses the results of conservative surgery for large lower pole breast cancers by lumpectomy associated with a bilateral remodelling mammoplasty, in order to avoid residual deformities.
  
  
  METHODS
  This retrospective study concerns 50 patients with a lower pole breast cancer treated between 1986 and 1996 by lumpectomy, mammoplasty and irradiation. The contralateral breast was immediately made symmetrical in all cases. The mean tumour size was 32.5 mm.
  
  
  RESULTS
  The mean weight of the lumpectomy specimen was 270 g. Resection margins were tumour-free in 90% of cases. The main complication observed was delayed healing, thus postponing post-operative treatment in 6.5% of cases. The median follow-up was 48 months. The 5-year actuarial ipsilateral local recurrence rate was 7% and 5-year actuarial metastasis-free and overall survival rates were 81 and 97%, respectively. Cosmesis was satisfactory in 85% of patients. We observed better results when radiotherapy was performed after rather than prior to surgery (92 vs. 67%: NS).
  
  
  CONCLUSIONS
  Performing a bilateral mammoplasty at the time of initial surgery for large breast cancers situated in the lower quadrants of the breast facilitates larger lumpectomies with good cosmetic results.
authors.affiliation: Department of Surgery, Institut Curie, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Nos
authors.forename: A
authors.initials: A
authors.lastname: Fitoussi
authors.forename: D
authors.initials: D
authors.lastname: Bourgeois
authors.forename: A
authors.initials: A
authors.lastname: Fourquet
authors.forename: R J
authors.initials: RJ
authors.lastname: Salmon
authors.forename: K B
authors.initials: KB
authors.lastname: Clough
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000379:methods*; D015412:Mastectomy, Segmental; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D016896:Treatment Outcome