Glutathione depletion enhances germ cell toxicity of butadiene metabolites: a flow cytometric study.
Cordelli
E
E
Section of Toxicology & Biomedical Sciences, ENEA CR Casaccia, Rome, Italy.
Leter
G
G
Pacchierotti
F
F
Tiveron
C
C
Spanò
M
M
D000818:Animals; D002070:Butadienes / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D004247:DNA / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004852:Epoxy Compounds / Q000494:pharmacology*; D005434:Flow Cytometry; D005978:Glutathione / Q000037:antagonists & inhibitors / Q000502:physiology*; D007659:Ketones / Q000494:pharmacology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009929:Organ Size / Q000187:drug effects; D013087:Spermatids / Q000166:cytology / Q000187:drug effects / Q000648:ultrastructure; D013093:Spermatogonia / Q000166:cytology / Q000187:drug effects / Q000648:ultrastructure; D013737:Testis / Q000033:anatomy & histology / Q000187:drug effects* / Q000648:ultrastructure; D013997:Time Factors
D002070:Butadienes; D004852:Epoxy Compounds; D007659:Ketones; C007366:diepoxybutane; C018637:phorone; D004247:DNA; D005978:Glutathione; C031763:1,3-butadiene