title: [Serological properties of HIV-1 isolates from the focus of an epidemic in the Gomel region of the Belarus Republic (1996)].
abstract: Immunoreactivity of sera obtained in 1996 from HIV-1-infected intravenous narcomaniacs from an epidemic focus in Gomel region, Belarus, is studied with a panel of 10-16-component synthetic peptides simulating apical epitope of surface glycoprotein gp120 V3 loop of HIV-1 variants. Comparative analysis of resultant spectra with representative immunoreactivity spectra of sera from a sampling of HIV-1-positive sera collected in 1986-1997 in different regions of the former USSR demonstrated a high homogeneity of immunoreactivity spectra of sera from Gomel region. Serotypes of HIV-1 A/C variants circulating in populations of intravenous narcomaniacs in the focus in Gomel region in 1996 and in Southern and South-Eastern Ukraine in 1995-1996 are similar. This confirms a previous conclusion about the prevalence of A/C serotype among intravenous narcomaniacs in the former USSR.
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Shchelkanov
authors.forename: N G
authors.initials: NG
authors.lastname: Iaroslavtseva
authors.forename: A N
authors.initials: AN
authors.lastname: Iudin
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Mirskov
authors.forename: V F
authors.initials: VF
authors.lastname: Eremin
authors.forename: L P
authors.initials: LP
authors.lastname: Titov
authors.forename: P G
authors.initials: PG
authors.lastname: Rytik
authors.forename: E V
authors.initials: EV
authors.lastname: Karamov
mesh_terms: D004197:Disease Reservoirs; D015699:HIV Envelope Protein gp120 / Q000276:immunology; D015658:HIV Infections / Q000453:epidemiology / Q000821:virology*; D015497:HIV-1 / Q000145:classification* / Q000276:immunology; D006801:Humans; D010446:Peptide Fragments / Q000276:immunology; D002094:Republic of Belarus / Q000453:epidemiology; D012703:Serotyping; D015819:Substance Abuse, Intravenous
chemical_list: D015699:HIV Envelope Protein gp120; C059762:HIV envelope protein gp120 (305-321); D010446:Peptide Fragments
vernacular_title: Serologicheskie svoĭstva izoliatov VICh-1 iz ochaga épidemii v Gomel'skoĭ oblasti Respubliki Belarus' (1996 g.).