[Castleman's disease and chromophobe carcinoma of the kidney. An incidental association?].
We report a case of Castleman's disease in a 65-year-old female, revealed by a renal tumor associated with inter-aortico-cava adenopathies and renal chromophobe cell carcinoma. This observation points to the difficulties in differentiating local Castleman's disease, which may be cured by surgical excision, from multicentric disease associated with a dysimmune syndrome of uncertain prognosis. The association of multicentric Castleman's disease with a carcinoma has rarely been described. It could be the emergence of a neoplasia in a context of dysimmunity or Castleman's disease might be related to the production of interleukin 6 by a renal carcinoma.
Tissier
F
F
Service d'Anatomie Pathologique, CHU Cochin Port-Royal, Paris.
de Pinieux
G
G
Thiounn
N
N
Merran
S
S
Gessain
A
A
Tulliez
M
M
Vieillefond
A
A
D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis*; D000368:Aged; D005871:Castleman Disease / Q000150:complications*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications / Q000175:diagnosis*
Maladie de Castleman et carcinome chromophobe du rein. Une association fortuite?