title: The Yeast Proteome Database (YPD): a model for the organization and presentation of genome-wide functional data.
abstract: The Yeast Proteome Database (YPD) is a model for the organization and presentation of comprehensive protein information. Based on the detailed curation of the scientific literature for the yeast Saccharomyces cerevisiae, YPD contains more than 50 000 annotations lines derived from the review of 8500 research publications. The information concerning each of the approximately 6100 yeast proteins is structured around a convenient one-page format, the Yeast Protein Report, with additional information provided as pop-up windows. Protein classification schema have been revised this year, defining each protein's cellular role, function and pathway, and adding a Functional to the Yeast Protein Report. These changes provide the user with a succinct summary of the protein's function and its place in the biology of the cell, and they enhance the power of YPD Search functions. Precalculated sequence alignments have been added, to provide a crossover point for comparative genomics. The first transcript profiling data has been integrated into the YPD Protein Reports, providing the framework for the presentation of genome-wide functional data. The Yeast Proteome Database can be accessed on the Web at http://www.proteome.com/YPDhome.html
authors.affiliation: Proteome Inc., 100 Cummings Center, Suite 435M, Beverly, MA 01915, USA.
authors.forename: P E
authors.initials: PE
authors.lastname: Hodges
authors.forename: A H
authors.initials: AH
authors.lastname: McKee
authors.forename: B P
authors.initials: BP
authors.lastname: Davis
authors.forename: W E
authors.initials: WE
authors.lastname: Payne
authors.forename: J I
authors.initials: JI
authors.lastname: Garrels
mesh_terms: D019295:Computational Biology; D016208:Databases, Factual / Q000639:trends; D005656:Fungal Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D016681:Genome, Fungal; D016247:Information Storage and Retrieval; D020407:Internet; D012106:Research; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism; D016415:Sequence Alignment; D012984:Software
chemical_list: D005656:Fungal Proteins