[Phospholipid composition of different rat brain regions in acute alcoholic intoxication].
The effect of acute ethanol intoxication (25% solution, intragastrically, 4 g/kg, 1 h) on the concentration of phospholipid fractions in different rat brain regions was studied. It was found that acute alcohol intoxication decreased the level of phosphatidylcholine and increased the concentration of phosphatidylethanolamine in the cerebellum of experimental animals. The cortex of large hemispheres showed a decreased amount of phosphatidylcholine and increased one of sphingomyelin. Possible mechanisms of these changes are discussed.
Selevich
M I
MI
Grodno State Medical Institute, Belarus.
Lelevich
V V
VV
D000818:Animals; D001921:Brain / Q000378:metabolism*; D001933:Brain Stem / Q000378:metabolism; D002531:Cerebellum / Q000378:metabolism; D002540:Cerebral Cortex / Q000378:metabolism; D000431:Ethanol / Q000506:poisoning*; D008297:Male; D010713:Phosphatidylcholines / Q000378:metabolism; D010714:Phosphatidylethanolamines / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats; D013109:Sphingomyelins / Q000378:metabolism
D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010743:Phospholipids; D013109:Sphingomyelins; D000431:Ethanol
Fosfolipidnyĭ sostav razlichnykh otdelov golovnogo mozga krys pri ostroĭ alkogol'noĭ intoksikatsii.