[Comparative study of the analyzers L-9100 (Merck-Hitachi) and HA-8121 (Menarini) for the determination of glycosylated hemoglobin].
A comparison study about the determination of HbA1c by L-9100 (Merck Hitachi) and HA-8121 (Menarini) was made. HbA1c was measured by high pressure liquid chromatography (HPLC). The within-run imprecision was CV < 3% (for HA-8121) and CV < 4.9% (for L-9100). The between-run imprecision was CV < 1% (for L-9100) and CV < 2% (for HA-121). Analysis of means (Student test) showed that both instruments were statistically different for HbA1Ac measurements (p < 0.001). The results of regression analysis (Passsing-Bablock test) were as follows: y = 0.88x + 0.58 (y = L-9100, r = 0.982, p = 0.005). In conclusion, the results showed that there are statistical differences between both instruments. Regression and correlation was good, but the data also showed that there is a constant and proportional error. We must make a new reference range values.
Quetglas
P
P
Laboratorio del Carmen, Hospital Universitario Son Dureta, Palma de Mallorca.
Llompart
I
I
Ferrer
M
M
Parera
M
M
Ribes
J L
JL
Guix
P
P
Fuentespina
E
E
D002851:Chromatography, High Pressure Liquid; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity
D006442:Glycated Hemoglobin; D011933:Reagent Kits, Diagnostic
Estudio comparativo de los analizadores L-9100 (Merck-Hitachi) y HA-8121 (Menarini) para la determinación de hemoglobina glucosilada.