title: [A study on familial aggregation of hepatitis virus infection in Fujian province].
abstract: In nine disease surveillance points of Fujian Province, positive serum antibody against hepatitis A virus (anti-HAV), hepatitis B surface antigen (HBsAg), antibody against hepatitis Cvirus (anti-HCV) and antibody against hepatitis E virus (anti-HEV) in people of 1,237 families were determined and their distribution was analyzed to study familial aggregation of hepatitis virus infection by fitting to binomial distribution. Results showed that chi 2 of goodness-of-fit to binomial distribution was 49.89, 217.91 and 27.39 for anti-HAV, HBsAg and anti-HEV respectively, all with P < 0.001, indicating very obvious familial aggregation in HAV, HBV and HEV infection, with aggregation rates of 84.13%, 34.83% and 35.23% respectively. It suggests that familial aggregation is mainly caused by mother to infant transmission and horizontal transmission in families, and HEV infection can be transmitted through sex.
authors.affiliation: Fujian Provincial Sanitation and Antiepidemic Station, Fuzhou.
authors.forename: L
authors.initials: L
authors.lastname: Li
authors.forename: Y
authors.initials: Y
authors.lastname: Zhou
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
mesh_terms: D016010:Binomial Distribution; D002681:China; D018562:Disease Transmission, Infectious; D005192:Family Health; D005260:Female; D006506:Hepatitis A / Q000635:transmission; D006509:Hepatitis B / Q000635:transmission*; D006526:Hepatitis C / Q000635:transmission; D016751:Hepatitis E / Q000635:transmission; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D008297:Male