title: [Ca2+/H+ exchange in the lymphocyte plasma membrane].
abstract: We studied delta pH-induced Ca(2+)-transport through the lymphocytes plasma membrane. The simultaneous and reversal H(+)-counter transport of Ca2+ was shown in the presence of known Ca(2+)- and H(+)-transporting pathways through the plasma membrane. Ca2+/H+ exchange through the plasma membrane was shown experimentally on the plasma membrane of lymphocytes, obtained from fresh rats' blood under the conditions of inhibition for known Ca2+ and H+ conductive pathways. At least one of the transporting cations' concentration gradient through the outer plasma membrane was only the moving force for the such exchange. Cytoplasmic H(+)-buffering capacity changing and associated plasma membrane's delta pH changing are discussed to imply on redistribution of Ca2+ through the plasma membrane. We suggest the presence of Ca2+/H+ antiporter in the lymphocytes' plasma membrane.
authors.affiliation: O.V. Palladin Institute of Biochemistry, NAS Ukraine, Kyiv.
authors.forename: A V
authors.initials: AV
authors.lastname: Bevza
authors.forename: S M
authors.initials: SM
authors.lastname: Kucherenko
mesh_terms: D000818:Animals; D001692:Biological Transport / Q000502:physiology; D002118:Calcium / Q000493:pharmacokinetics*; D002352:Carrier Proteins / Q000502:physiology; D002462:Cell Membrane / Q000502:physiology; D006863:Hydrogen-Ion Concentration; D008214:Lymphocytes / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats
chemical_list: D002352:Carrier Proteins; D002118:Calcium
vernacular_title: Ca2+/H+ obmin u plazmatychniĭ membrani limfotsytiv.