title: Rheolytic thrombectomy in the treatment of acute limb-threatening ischemia: immediate results and six-month follow-up of the multicenter AngioJet registry. Possis Peripheral AngioJet Study AngioJet Investigators.
abstract: We tested the efficacy of rheolytic thrombectomy in treating 21 patients (mean age 68+/-12 years; 66% male) and 22 vessels (limbs) who presented to the hospital within 2 weeks of the development of limb-threatening ischemia. Fifty-two percent had contraindications to use thrombolytics, and 57% had severe comorbidities. All of the vessels were occluded with thrombus on the initial angiogram. Procedural success was achieved in 20 limbs (91%). Three patients expired in the hospital, and one expired at follow-up due to nonvascular causes. Acute limb salvage was achieved in 18 of 19 limbs (95%) in the 18 survivors, and 6-month limb salvage was achieved in 16 of 18 limbs (89%) in the 17 survivors. Rheolytic thrombectomy is effective in restoring immediate blood flow in acute limb-threatening ischemia, especially in high-risk surgical patients or patients with contraindications to thrombolytic therapy.
authors.affiliation: Department of Cardiology, Ochsner Clinic, New Orleans, Louisiana 70121, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Silva
authors.forename: S R
authors.initials: SR
authors.lastname: Ramee
authors.forename: T J
authors.initials: TJ
authors.lastname: Collins
authors.forename: J S
authors.initials: JS
authors.lastname: Jenkins
authors.forename: A J
authors.initials: AJ
authors.lastname: Lansky
authors.forename: G M
authors.initials: GM
authors.lastname: Ansel
authors.forename: B L
authors.initials: BL
authors.lastname: Dolmatch
authors.forename: M H
authors.initials: MH
authors.lastname: Glickman
authors.forename: B
authors.initials: B
authors.lastname: Stainken
authors.forename: E
authors.initials: E
authors.lastname: Ramee
authors.forename: C J
authors.initials: CJ
authors.lastname: White
mesh_terms: D000368:Aged; D002404:Catheterization / Q000295:instrumentation*; D015897:Comorbidity; D004867:Equipment Design; D005121:Extremities / Q000098:blood supply*; D005260:Female; D005500:Follow-Up Studies; D006083:Graft Occlusion, Vascular / Q000601:surgery; D006801:Humans; D007511:Ischemia / Q000453:epidemiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012212:Rheology; D017131:Thrombectomy / Q000295:instrumentation* / Q000379:methods; D013927:Thrombosis / Q000601:surgery*; D016896:Treatment Outcome