title: [Morphofunctional disorders of uterine-placenta blood flow in multiple uterine myomas].
abstract: Results of the right uterine artery dopplerometry at pregnancy 39-39 weeks and those of subsequent histotopographic and immunomorphologic study of the placental bed in the amputated uteri were compared in 50 pregnant women. Morphofunctional equivalent of a considerable reduction of the uterine-placental circulation depending on the myomatous tissue spread and particularly in rare observations of "the placenta on the node" were found. Pathogenesis of these disturbances is determined by deficiency of the second wave of interstitial cytotrophoblast invasion, by phenomenon of the uterine-placental circulation decrease due to arterial supply of myomatous nodes and local hormonal changes produced by alterations of cellular-tissular correlations in the uterine-placental bed.
authors.affiliation: Research Institute of Human Morphology, Moscow.
authors.forename: A P
authors.initials: AP
authors.lastname: Milovanov
authors.forename: I S
authors.initials: IS
authors.lastname: Sidorova
authors.forename: O I
authors.initials: OI
authors.lastname: Trushina
authors.forename: M
authors.initials: M
authors.lastname: Kadyrov
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D018231:Leiomyomatosis / Q000473:pathology* / Q000503:physiopathology; D008875:Middle Aged; D021041:Placental Circulation; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000503:physiopathology; D014594:Uterine Neoplasms / Q000473:pathology* / Q000503:physiopathology
vernacular_title: Morfofunktsional'nye narusheniia matochno-platsentarnogo krovotoka pri mnozhestvennykh miomakh matki.