title: Modulation of immunoglobulin dysregulation in graft versus host-and systemic lupus erythematosus-like diseases by malononitrilamides.
authors.affiliation: Research Laboratories Hoechst Marion Roussel Deutschland GmbH, Wiesbaden, Germany.
authors.forename: H U
authors.initials: HU
authors.lastname: Schorlemmer
authors.forename: R R
authors.initials: RR
authors.lastname: Bartlett
mesh_terms: D020106:Acrylamide / Q000627:therapeutic use; D000178:Acrylamides; D000480:Alkynes; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D001323:Autoantibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000188:drug therapy* / Q000276:immunology; D002208:Caproates / Q000627:therapeutic use*; D003433:Crosses, Genetic; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology; D006086:Graft vs Host Disease / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D007073:Immunoglobulin E / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007555:Isoxazoles; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy* / Q000382:microbiology; D017710:Lymphocyte Transfusion; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D008817:Mice, Mutant Strains; D009570:Nitriles; D013154:Spleen / Q000276:immunology; D014184:Transplantation, Homologous
chemical_list: D000178:Acrylamides; D000480:Alkynes; D001323:Autoantibodies; D002208:Caproates; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D009570:Nitriles; C115284:2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide; D020106:Acrylamide; C116406:HMR 1279; D007073:Immunoglobulin E