title: An epidemiological study of multiple sclerosis in central Sardinia, Italy.
abstract: OBJECTIVE
  To verify morbidity estimates in central Sardinia, Italy.
  
  
  METHODS
  A prevalence study was performed in the province of Nuoro, Central Sardinia, which has a population of 273,768 inhabitants (135,383 men and 138,385 women). A complete enumeration approach was adopted by using all possible case-collection sources.
  
  
  RESULTS
  On prevalence day, December 31, 1993, 394 subjects (124 men and 270 women) living in the study area were known to suffer from definite and probable MS, giving a crude prevalence rate of 143.9 cases per 100,000 people, 91.6 for males and 195.11 for females. The crude prevalence estimated on December 31, 1985, based on 282 MS cases alive in the study area, was 102.94 per 100,000.
  
  
  CONCLUSIONS
  This study reinforced central Sardinia's position as a high and rising prevalence area for MS.
authors.affiliation: Clinica Neurologica, Dipartimento di Discipline Medico-Chirurgiche della Comunicazione e del Comportamento, Centro Sclerosi Multipla, Università di Ferrara, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Casetta
authors.forename: E
authors.initials: E
authors.lastname: Granieri
authors.forename: D
authors.initials: D
authors.lastname: Marchi
authors.forename: S B
authors.initials: SB
authors.lastname: Murgia
authors.forename: M R
authors.initials: MR
authors.lastname: Tola
authors.forename: A
authors.initials: A
authors.lastname: Ticca
authors.forename: G
authors.initials: G
authors.lastname: Lauria
authors.forename: V
authors.initials: V
authors.lastname: Govoni
authors.forename: B
authors.initials: B
authors.lastname: Murgia
authors.forename: M
authors.initials: M
authors.lastname: Pugliatti
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000453:epidemiology*; D015995:Prevalence; D012737:Sex Factors