title: Hydralazine-induced lupus and vocal fold paralysis.
abstract: Systemic lupus erythematosus (SLE) is a multi-system autoimmune disorder that can affect the upper airway. Hydralazine has been known to cause a lupus-like syndrome that can produce the clinical manifestations of SLE. We discuss a case of hydralazine-induced lupus, presenting with acute laryngeal oedema and right vocal fold paralysis. Cessation of hydralazine therapy resulted in reversal of paralysis.
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, Royal Gwent Hospital, Newport, U.K.
authors.forename: C K
authors.initials: CK
authors.lastname: Hari
authors.forename: S A
authors.initials: SA
authors.lastname: Raza
authors.forename: M I
authors.initials: MI
authors.lastname: Clayton
mesh_terms: D000959:Antihypertensive Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006830:Hydralazine / Q000009:adverse effects*; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D008875:Middle Aged; D014826:Vocal Cord Paralysis / Q000139:chemically induced*
chemical_list: D000959:Antihypertensive Agents; D006830:Hydralazine