A novel synthesis of fused pyrazole systems as antimicrobial agents.
The pyrazolo[3,4-b]pyridine derivatives 3 could be prepared by condensing compounds 1 with the 3-aminopyrazolone derivative 2. The pyrazolo[5,2-b]-1,3-oxazine derivative 11 and polyfunctionally substituted 1,4-dihydropyridines 15, 18 were also synthesized. Some of the obtained compounds were tested for their antimicrobial activity.
Erian
A W
AW
Chemistry Department, Faculty of Science, Cairo University, Giza, Egypt.
el-Gohary
S
S
Manhi
F M
FM
Ali
F A
FA
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D015169:Colony Count, Microbial; D005658:Fungi / Q000187:drug effects; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D011720:Pyrazoles