title: Statistical evaluation of in vitro dissolution of different brands of ciprofloxacin hydrochloride tablets and capsules.
abstract: The in vitro dissolution of ciprofloxacin from commercially available tablets and capsules in China was studied using the USP apparatus I to compare the product performance from nine different manufacturers. Cumulative release greater than 75% was obtained from all of the products tested within 45 min. However, statistically significant differences were found between some of the products when in vitro data were analyzed using the Weibull function, similarity factor (f2), and multivariate analysis of variances.
authors.affiliation: Department of Pharmacy, Chang Shu No. 1 People's Hospital, Jiangsu, People's Republic of China.
authors.forename: Y
authors.initials: Y
authors.lastname: Tang
authors.forename: K
authors.initials: K
authors.lastname: Gan
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage* / Q000737:chemistry / Q000493:pharmacokinetics; D002214:Capsules; D002626:Chemistry, Pharmaceutical; D002681:China; D002939:Ciprofloxacin / Q000008:administration & dosage* / Q000737:chemistry / Q000493:pharmacokinetics; D003627:Data Interpretation, Statistical; D006801:Humans; D066298:In Vitro Techniques; D013607:Tablets
chemical_list: D000890:Anti-Infective Agents; D002214:Capsules; D013607:Tablets; D002939:Ciprofloxacin