title: Ultrastructural features of diffuse malignant mesotheliomas.
abstract: The distinction of malignant mesothelioma from tumors metastatic to the serosal membranes can often be made based on the results of histochemical or immunohistochemical studies. However, in some cases, these techniques are inadequate to make a firm diagnosis. In these instances, electron microscopic studies with the observation of a constellation of characteristic ultrastructural findings may permit an unequivocal diagnosis of mesothelioma.
authors.affiliation: Department of Pathology, Duke University Medical Center, Durham, NC, USA.
authors.forename: T D
authors.initials: TD
authors.lastname: Oury
authors.forename: S P
authors.initials: SP
authors.lastname: Hammar
authors.forename: V L
authors.initials: VL
authors.lastname: Roggli
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000378:metabolism; D003594:Cytoplasmic Granules / Q000378:metabolism / Q000648:ultrastructure; D003937:Diagnosis, Differential; D006801:Humans; D006820:Hyaluronic Acid / Q000378:metabolism; D007150:Immunohistochemistry; D007365:Intercellular Junctions / Q000648:ultrastructure; D007382:Intermediate Filaments / Q000648:ultrastructure; D008654:Mesothelioma / Q000175:diagnosis* / Q000378:metabolism / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008871:Microvilli / Q000648:ultrastructure; D012509:Sarcoma / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure
chemical_list: D006820:Hyaluronic Acid