title: Differentiating human from animal isolates of Cryptosporidium parvum.
abstract: We analyzed 92 Cryptosporidium parvum isolates from humans and animals by a polymerase chain reaction/restriction fragment length polymorphism method based on the thrombospondin-related anonymous protein 2 gene sequence. Used as a molecular marker, this method can differentiate between the two genotypes of C. parvum and elucidate the transmission of infection to humans.
authors.affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
authors.forename: I M
authors.initials: IM
authors.lastname: Sulaiman
authors.forename: L
authors.initials: L
authors.lastname: Xiao
authors.forename: C
authors.initials: C
authors.lastname: Yang
authors.forename: L
authors.initials: L
authors.lastname: Escalante
authors.forename: A
authors.initials: A
authors.lastname: Moore
authors.forename: C B
authors.initials: CB
authors.lastname: Beard
authors.forename: M J
authors.initials: MJ
authors.lastname: Arrowood
authors.forename: A A
authors.initials: AA
authors.lastname: Lal
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology*; D003457:Cryptosporidiosis / Q000453:epidemiology / Q000469:parasitology* / Q000662:veterinary*; D016785:Cryptosporidium parvum / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D004196:Disease Outbreaks; D005838:Genotype; D006801:Humans; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D015800:Protozoan Proteins / Q000235:genetics*; D017422:Sequence Analysis, DNA
chemical_list: D015800:Protozoan Proteins; C069428:thrombospondin-related adhesive protein, protozoan