title: [The number of carotid artery operations in the Twente Medical Spectrum before and after the publication of relevant international research on the benefits of the relief of carotid stenosis].
abstract: OBJECTIVE
  To determine the effect of adequate scientific research on the treatment of extracranial stenosis of the internal carotid artery.
  
  
  METHODS
  Retrospective and comparative.
  
  
  METHODS
  Twenty Medical Spectrum, Enschede, the Netherlands.
  
  
  METHODS
  A comparison was made of the relevant data from 2 years of carotid artery surgery before (1989-1990; period I) and after the publication of two randomized multicentre studies (1994-1995; period II).
  
  
  RESULTS
  The number of patients treated surgically and the number of carotid artery desobstructions had increased during period II by 339% and 319%, respectively. In period I, 25% of the patients had an asymptomatic ipsilateral stenosis of the internal carotid artery; in period II, this had decreased to 11%. In period I, 65% of the patients had a stenosis in excess of 70% of the diameter of the vessel; in period II this was 85%. The combined mortality and permanent disabling morbidity after 30 days was 6% in period I and 3% in period II.
  
  
  CONCLUSIONS
  After the publication of two high-quality studies in 1991, the number of carotid artery operations increased by over 300%. The indications for the surgical treatment of stenosis were stricter rather than less strict in period II. The increase of the number of carotid desobstructions can be explained by the fact that GPs' and neurologists' referral to the vascular surgeon has changed. This change in the referring pattern may be the consequences of use of 'evidence-based' medicine.
authors.affiliation: Afd. Vaatchirurgie, Medisch Spectrum Twente, Enschede.
authors.forename: L M
authors.initials: LM
authors.lastname: Dijkema
authors.forename: R H
authors.initials: RH
authors.lastname: Geelkerken
authors.forename: P J
authors.initials: PJ
authors.lastname: Brouwers
authors.forename: P
authors.initials: P
authors.lastname: de Smit
authors.forename: R J
authors.initials: RJ
authors.lastname: van Det
mesh_terms: D000328:Adult; D000368:Aged; D016893:Carotid Stenosis / Q000150:complications / Q000401:mortality / Q000601:surgery*; D016894:Endarterectomy, Carotid / Q000379:methods / Q000706:statistics & numerical data*; D019317:Evidence-Based Medicine / Q000639:trends; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic / Q000592:standards; D009426:Netherlands; D010818:Practice Patterns, Physicians' / Q000639:trends; D016032:Randomized Controlled Trials as Topic; D012017:Referral and Consultation / Q000706:statistics & numerical data; D012086:Reoperation; D012189:Retrospective Studies; D015996:Survival Rate
vernacular_title: Het aantal carotisoperaties in het Medisch Spectrum Twente vóór en na de publicatie van belangrijk internationaal onderzoek naar het nut van A.-carotisdesobstructie.