title: Acute evaluation of a preformed single-pass VDD/DDD pacing lead.
abstract: The clinical utility of single lead, atrial synchronous, ventricular pacing (VDD), for patients with normal sinus function and heart block is well established. Atrial stimulation, unavailable in VDD systems presents a significant disadvantage. DDD pacing systems however, require the introduction and positioning of two separate leads. The acute human study discussed evaluated a modified version of a commercially available VDD lead with a preshaped lobe, capable of both sensing and pacing the right atrium. "P" waves and atrial stimulation thresholds were determined in five patients. The mean P-wave was 2.5 +/- 1 millivolts. Atrial stimulation in the unipolar configuration was 1.6 +/- 0.5 volts and 1.7 +/- 0.9 volts in the bipolar configuration. These acute stimulation thresholds and sensing amplitudes were comparable to conventional DDD pacing systems. Therefore, single-lead DDD pacing may be feasible and warrants further study.
authors.affiliation: Division of Cardiology, Orlando Regional Healthcare Systems Orlando, Florida, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Hazday
authors.forename: D
authors.initials: D
authors.lastname: Mendelson
authors.forename: R R
authors.initials: RR
authors.lastname: Brownlee
mesh_terms: D002304:Cardiac Pacing, Artificial / Q000379:methods; D004562:Electrocardiography; D004567:Electrodes, Implanted; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D006325:Heart Atria; D006327:Heart Block / Q000628:therapy; D006352:Heart Ventricles; D006801:Humans; D007495:Iridium; D010138:Pacemaker, Artificial; D010984:Platinum; D013499:Surface Properties
chemical_list: D007495:Iridium; D010984:Platinum