title: Laryngeal cancer in Lower Silesia: descriptive analysis of 501 cases.
abstract: This paper presents a descriptive analysis of 501 cases of laryngeal cancer. The patients were classified according to their age, sex, primary tumour localisation and stage. There were 448 males and 53 females, with a male-to-female ratio of 8.5:1. The peak incidence of cancer was detected in the 6th and 7th decades of age. The most common primary tumour localisation was the glottis. Three-hundred-and-forty patients presented at advanced tumour stages (T3/T4). The proportion of patients presenting matastatic neck nodes was 29.3% and the incidence of metastatic lymph nodes increased with increasing T stage. Histopathological analysis revealed that 98% of tumours were squamous cell carcinomas. There were 125 well-differentiated, 235 moderately differentiated and 133 poorly differentiated carcinomas. Among other tumours, there was 1 adenoid squamous cell carcinoma, 1 giant cell carcinoma, 1 adenoma pleomorphicum, 1 adenoid cystic carcinoma (cylindroma), 1 haemangiopericytoma, 1 verrucous cell carcinoma, 1 lymphoepithelioma and 1 granular cell tumour.
authors.affiliation: Department and Clinic of Otolaryngology, Medical University of Wrocław, Poland.
authors.forename: T
authors.initials: T
authors.lastname: Krecicki
authors.forename: M
authors.initials: M
authors.lastname: Zalesska-Krecicka
authors.forename: M
authors.initials: M
authors.lastname: Jagas
authors.forename: K
authors.initials: K
authors.lastname: Szajowski
authors.forename: J
authors.initials: J
authors.lastname: Rak
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D007822:Laryngeal Neoplasms / Q000453:epidemiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011044:Poland / Q000453:epidemiology; D017678:Sex Distribution