Hyperammonaemic encephalopathy after a subureteric injection for vesicoureteric reflux.
A 6 year old boy developed hyperammonaemic encephalopathy following a subureteric injection for treatment of vesicoureteric reflux. The hyperammonaemia may be explained by a postoperative urinary tract infection with a urea splitting organism, leading to raised urine ammonia that was absorbed easily across a dilated urinary tract. Agitation and alteration in consciousness level following a urological procedure, in a child with a dilated urinary tract, may be signs of a treatable hyperammonaemic encephalopathy.
Zuberi
S M
SM
Department of Neurology, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK.
Stephenson
J B
JB
Azmy
A F
AF
Robinson
P H
PH
McWilliam
R C
RC
D000641:Ammonia / Q000097:blood*; D001921:Brain / Q000000981:diagnostic imaging; D002545:Brain Ischemia / Q000097:blood / Q000000981:diagnostic imaging / Q000209:etiology*; D002648:Child; D003128:Coma / Q000097:blood / Q000139:chemically induced*; D004724:Endoscopy; D006801:Humans; D007267:Injections; D008297:Male; D014057:Tomography, X-Ray Computed; D014552:Urinary Tract Infections / Q000150:complications*; D014718:Vesico-Ureteral Reflux / Q000097:blood / Q000000981:diagnostic imaging / Q000601:surgery*
D000641:Ammonia