title: Effects of electromagnetic fields on membrane ion transport of cultured cells.
abstract: We have studied the mechanisms of ion transport mediated by Na+/K(+)-pump and Na+,K+,Cl(-)-cotransport pathway of HeLa cells using Rb+ as an analog for K+, and proposed models of binding of ions for the transport pathways. Also, we clarified the relation between ion and water movements in the cells. Based on these findings, we have studied the effects of homogeneous and time-varying magnetic fields on the ion transport activity. The research presented here covers (i) brief explanations of our kinetic studies on the ion transport pathways for promoting understanding of the effects of magnetic fields on the pathways, (ii) our and other reports of the effects of magnetic fields on ion transport systems.
authors.affiliation: Department of Physiology, University of Tokushima School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ikehara
authors.forename: H
authors.initials: H
authors.lastname: Yamaguchi
authors.forename: H
authors.initials: H
authors.lastname: Miyamoto
mesh_terms: D002352:Carrier Proteins / Q000378:metabolism*; D048429:Cell Size; D004574:Electromagnetic Fields; D055590:Electromagnetic Phenomena / Q000295:instrumentation; D006367:HeLa Cells / Q000378:metabolism / Q000528:radiation effects; D006801:Humans; D017136:Ion Transport / Q000528:radiation effects*; D007700:Kinetics; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008564:Membrane Potentials / Q000528:radiation effects; D009363:Neoplasm Proteins / Q000378:metabolism; D011188:Potassium / Q000378:metabolism*; D012413:Rubidium / Q000378:metabolism; D015398:Signal Transduction / Q000528:radiation effects; D028021:Sodium-Potassium-Chloride Symporters; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*; D014867:Water / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D009363:Neoplasm Proteins; D028021:Sodium-Potassium-Chloride Symporters; D014867:Water; D000254:Sodium-Potassium-Exchanging ATPase; D012413:Rubidium; D011188:Potassium