title: Infection with group C rotavirus in a suburban community in Brazil.
abstract: Group C rotaviruses are associated with sporadic outbreaks of gastroenteritis worldwide. Age-specific seroprevalence of group C rotavirus antibodies was investigated in sera, randomly collected and representative of a suburban community in Brazil which had previously been screened for group A rotavirus antibodies. Antibody prevalence to group C rotavirus was low in children under 5 years and increased slowly with age to 36% seropositivity in adults, reflecting continuous exposure to primary infection in all age groups. This suggests a higher incidence of infection than disease might predict. Adult antibody prevalence was similar to that in other geographical settings. No obvious patterns of infection with group A and group C rotavirus were found within individuals, which suggests independent transmission. However, further epidemiological studies are required to understand group C rotavirus dynamics and possible interactions with group A rotavirus transmission and immunity.
authors.affiliation: Department of Biological Sciences, University of Warwick, Coventry, UK. cox@oikos.warwick.ac.uk
authors.forename: M J
authors.initials: MJ
authors.lastname: Cox
authors.forename: V L
authors.initials: VL
authors.lastname: James
authors.forename: R S
authors.initials: RS
authors.lastname: Azevedo
authors.forename: E
authors.initials: E
authors.lastname: Massad
authors.forename: G F
authors.initials: GF
authors.lastname: Medley
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000635:transmission; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral