title: [Clinical study on effect of bushen shengxue paste in treating renal anemia patients].
abstract: OBJECTIVE
  To evaluate the therapeutical mechanism of Bushen Shengxue Paste (BSSXP) on anemia.
  
  
  METHODS
  Chronic renal failure induced anemia patients were treated with BSSXP, clinical manifestation, anemia and renal function as indicators were observed in patients. The erythropoietin (EPO) and inhibition of colony-forming unit-erythrocyte (CFU-E) in patients' serum were determined by CFU-E in vitro.
  
  
  RESULTS
  The patients' symptoms, renal function and anemia were improved after administration with BSSXP 1-2 course. EPO in serum was slightly increased. The inhibition of CFU-E in patient's serum was significantly decreased.
  
  
  CONCLUSIONS
  BSSXP could improve the anemia degree, its mechanism might be through clearing the inhibitor of CFU-E in serum.
authors.affiliation: Institute of Radiation Medicine, Shanghai Medical University.
authors.forename: X
authors.initials: X
authors.lastname: Dong
authors.forename: G X
authors.initials: GX
authors.lastname: Shan
authors.forename: H D
authors.initials: HD
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000740:Anemia / Q000097:blood / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004906:Erythrocyte Count; D015672:Erythroid Precursor Cells / Q000473:pathology; D004921:Erythropoietin / Q000097:blood; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
chemical_list: D004365:Drugs, Chinese Herbal; D006454:Hemoglobins; D004921:Erythropoietin