title: Serum hepatocyte growth factor level associate with gastric cancer progression.
abstract: We have measured serum HGF levels from 80 gastric cancer patients and 51 normal subjects by enzyme-linked immunosorbent assay. The results showed that the mean value of serum HGF level in gastric cancer patients was significantly higher than in normal subjects (0.30 +/- 0.02 vs 0.22 +/- 0.05 ng/ml; p = 0.005). The increase was stage related. Patients with serum HGF < or = 0.30 ng/ml survived longer than those with serum HGF > 0.30 ng/ml (p = 0.02). These data suggest that HGF involve in progression of gastric cancer.
authors.affiliation: Department of Surgery, Veterans General Hospital-Taipei, Taiwan, Republic of China. cwwu@isc1.vghtpe.gov.tw
authors.forename: C W
authors.initials: CW
authors.lastname: Wu
authors.forename: C W
authors.initials: CW
authors.lastname: Chi
authors.forename: T L
authors.initials: TL
authors.lastname: Su
authors.forename: T Y
authors.initials: TY
authors.lastname: Liu
authors.forename: W Y
authors.initials: WY
authors.lastname: Lui
authors.forename: F K
authors.initials: FK
authors.lastname: P'eng
mesh_terms: D000230:Adenocarcinoma / Q000097:blood* / Q000378:metabolism / Q000401:mortality / Q000556:secondary; D000368:Aged; D018450:Disease Progression; D005260:Female; D017228:Hepatocyte Growth Factor / Q000097:blood*; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D009363:Neoplasm Proteins / Q000097:blood*; D013274:Stomach Neoplasms / Q000097:blood* / Q000378:metabolism / Q000401:mortality / Q000473:pathology; D016019:Survival Analysis
chemical_list: D009363:Neoplasm Proteins; D017228:Hepatocyte Growth Factor