title: Perils, pitfalls, and accomplishments of guidelines for treatment of back problems.
abstract: Science should be the basis for guidelines. As a result of the Flexner Report in 1911, we now live in an era where randomized trials are available. Statistical methods can truly be applied to evaluate the reliability of data published in the literature. The result is that we can now demand more from future publications and allow for a better evaluation of the mistakes or bias that can distort validity, applicability, and reliability. The importance of this methodology is to reduce misunderstandings by patients, clinicians, manufacturers, and government agencies about issues important to patient care.
authors.affiliation: University of Washington School of Medicine, Seattle, Washington 98104, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: Bigos
mesh_terms: D003431:Cross-Cultural Comparison; D006801:Humans; D017116:Low Back Pain / Q000209:etiology / Q000534:rehabilitation*; D010043:Outcome and Process Assessment, Health Care; D010348:Patient Care Team; D017410:Practice Guidelines as Topic; D011785:Quality Assurance, Health Care