[Effects of green tea on growth inhibition and immune regulation of Lewis lung cancer in mice].
C57/BL6J mice were inoculated with Lewis lung cancer cells as an experimental model to study the effects of green tea on cancer prevention, inhibition of tumor growth and immune regulation in mice with tumor. Results showed that weight of thymus in C57/BL6J mice and its index declined, proportion of positive CD4 subgroup of T lymphocyte and ratio of CD4+, to CD8+ reduced, baseline chemilumi-nescence decreased in peripheral white blood cells, yeast zymosan stimulated chemiluminescence increased, and number of immunoglobulin M formation cells decreased. It indicated that green tea had obvious inhibition in Lewis lung cancer and protective effects, to various extent, on adverse changes of above indices.
Zhu
M
M
Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing.
Gong
Y
Y
Ge
G
G
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D016516:CD4-CD8 Ratio; D018827:Carcinoma, Lewis Lung / Q000276:immunology / Q000473:pathology*; D005260:Female; D066298:In Vitro Techniques; D007962:Leukocytes / Q000276:immunology; D008163:Luminescent Measurements; D051379:Mice; D008810:Mice, Inbred C57BL; D009368:Neoplasm Transplantation; D010936:Plant Extracts / Q000494:pharmacology; D013601:T-Lymphocytes / Q000276:immunology*; D013662:Tea
D000276:Adjuvants, Immunologic; D000970:Antineoplastic Agents; D010936:Plant Extracts; D013662:Tea