Splenic lymphoma presenting as necrotizing glomerulonephritis.
The authors report a case of necrotizing glomerulonephritis, with granular immune deposits, leading to the etiologic diagnosis of splenic non-Hodgkin's Lymphoma (NHL). The serum creatinine, initially markedly elevated, decreased under steroids and chlorambucil. Unfortunately, the patient died from septic complications. The importance of a careful search for a (localized) NHL in case of necrotizing glomerulonephritis with granular immune deposits is emphasized.
Messiaen
T
T
Department of Nephrology, Cliniques Universitaires St. Luc, University of Louvain Medical School, Brussels, Belgium.
Cosyns
J P
JP
Ferrant
A
A
Jadoul
M
M
D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D005921:Glomerulonephritis / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000175:diagnosis*; D009336:Necrosis; D013160:Splenic Neoplasms / Q000150:complications / Q000175:diagnosis*