title: Gastroesophageal reflux in neurologically impaired children: partial or total fundoplication?
abstract: BACKGROUND
  It is difficult to give guidelines when approaching gastroesophageal disease in neurologically impaired children. Indication for surgery has been increasing over recent years, but there is no consensus on the surgical technique of choice. Nothing has been written specifically comparing the results of different procedures in these patients, so far.
  
  
  METHODS
  We retrospectively compare the short- and long-term results of two different types of fundoplication in a series of children operated on for documented gastroesophageal reflux disease at our institution.
  
  
  RESULTS
  One group (group A) of 27 patients, operated on between 1977 and 1993, underwent Nissen fundoplication, the other (group B), formed of 20 patients all of whom were operated on between 1993 and 1995, underwent Thai fundoplication. We compared the results in terms of positive outcome (recovery) and negative outcome (minor and major complication), computing the relative odds of group A versus group B in terms of risk of complication, and we compared the mean operative time and the length of hospital stay by means of a student's t-test analysis.
  
  
  CONCLUSIONS
  Our results show that there is no statistical difference between the two procedures in terms of relative risk of complication and success rate. The duration of surgery and hospital stay were significantly shorter in group B. The Thal procedure can, therefore, be proposed as first choice in the management of these patients.
authors.affiliation: Department of Pediatric Surgery, Bambino Gesù Children's Hospital, Rome, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Ceriati
authors.forename: N
authors.initials: N
authors.lastname: Guarino
authors.forename: A
authors.initials: A
authors.lastname: Zaccara
authors.forename: P
authors.initials: P
authors.lastname: Marchetti
authors.forename: E
authors.initials: E
authors.lastname: la Sala
authors.forename: M C
authors.initials: MC
authors.lastname: Lucchetti
authors.forename: L
authors.initials: L
authors.lastname: Dall'Oglio
authors.forename: M
authors.initials: M
authors.lastname: Rivosecchi
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D018662:Fundoplication / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000150:complications / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D009422:Nervous System Diseases / Q000150:complications / Q000175:diagnosis; D016017:Odds Ratio; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome