title: [Regulatory components of the eukaryotic translation apparatus in normal states and after exposure to ionizing radiation].
abstract: The comparative analysis of content prostaglandins E2, F2 alpha and cAMP, cGMP in the compositions of the high-molecular aminoacyl-tRNA synthetase complexes and endoplasmic reticulum vesicules from the rat liver has been carried out. The influence of lethal and sublethal X-ray doses on the levels of cyclic nucleotides and prostaglandins has been studied. Cyclic nucleotides and prostaglandins proved to be rapid and high sensitive transmitters of ionizing radiation influence on the eukaryotic translation apparatus.
authors.affiliation: Taras Shevchenko National University, Kyiv, Ukraine.
authors.forename: R P
authors.initials: RP
authors.lastname: Vynohradova
authors.forename: O F
authors.initials: OF
authors.lastname: Zudina
authors.forename: O V
authors.initials: OV
authors.lastname: Khudiakova
authors.forename: S P
authors.initials: SP
authors.lastname: Imedadze
mesh_terms: D000604:Amino Acyl-tRNA Synthetases / Q000378:metabolism; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism; D006152:Cyclic GMP / Q000378:metabolism; D015237:Dinoprost / Q000378:metabolism; D015232:Dinoprostone / Q000378:metabolism; D008099:Liver / Q000201:enzymology / Q000378:metabolism / Q000528:radiation effects; D014176:Protein Biosynthesis / Q000528:radiation effects*; D051381:Rats; D014965:X-Rays
chemical_list: D015237:Dinoprost; D000242:Cyclic AMP; D000604:Amino Acyl-tRNA Synthetases; D006152:Cyclic GMP; D015232:Dinoprostone
vernacular_title: Reguliatorni komponenty aparatu transliatsiï eukariutiv u normi ta za diï ionizuiuchoï radiatsiï.