title: Splenic lymphoma presenting as necrotizing glomerulonephritis.
abstract: The authors report a case of necrotizing glomerulonephritis, with granular immune deposits, leading to the etiologic diagnosis of splenic non-Hodgkin's Lymphoma (NHL). The serum creatinine, initially markedly elevated, decreased under steroids and chlorambucil. Unfortunately, the patient died from septic complications. The importance of a careful search for a (localized) NHL in case of necrotizing glomerulonephritis with granular immune deposits is emphasized.
authors.affiliation: Department of Nephrology, Cliniques Universitaires St. Luc, University of Louvain Medical School, Brussels, Belgium.
authors.forename: T
authors.initials: T
authors.lastname: Messiaen
authors.forename: J P
authors.initials: JP
authors.lastname: Cosyns
authors.forename: A
authors.initials: A
authors.lastname: Ferrant
authors.forename: M
authors.initials: M
authors.lastname: Jadoul
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D005921:Glomerulonephritis / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000175:diagnosis*; D009336:Necrosis; D013160:Splenic Neoplasms / Q000150:complications / Q000175:diagnosis*