[A study on the relationship between plasma level of ET-1 and cGRP and blood pressure in hemodialysis patients].
Plasma endothelin-1 (ET-1) and calcitonin gene related peptides (cGRP) were studied by immunoradiological method in 60 hemodialysis (HD) patients. The results showed that: (1) Plasma level of ET-1 and cGRP were increased in the HD patients. (2) Plasma level of ET-1 and cGRP varied in different times of HD. (3) A significantly positive relation between plasma ET-1 and blood pressure (BP) existed in the HD patients, while a significantly negative relation between plasma cGRP and BP existed in the HD patients. The results suggest that ET-1 and cGRP are major factors which lead to BP changes in HD patients.
Zhou
Q
Q
Department of Internal Medicine, Xiangya Hospital, Hunan Medical University, Changsha.
Sun
M
M
Li
X
X
D000328:Adult; D001794:Blood Pressure; D015740:Calcitonin Gene-Related Peptide / Q000097:blood*; D019332:Endothelin-1 / Q000097:blood*; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000517:prevention & control; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000503:physiopathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis
D019332:Endothelin-1; D015740:Calcitonin Gene-Related Peptide