title: [Comparison of single sample methods for determination of plasma clearance using 99mTc-MAG3].
abstract: We compared relationship among three single blood sampling methods which have been proposed for determination of plasma clearance with 99mTc-MAG3. Russell's and Bubeck's algorithms were employed for 48 adults (average age: 53 years) and Bubeck's and Piepsz's algorithms were used in 9 children (average age: 5.8 years). Three methods showed very high correlation among them. However, Russell's and Piepsz's methods were about 1.4 times higher than Bubeck's method in calculating plasma clearance of 99mTc-MAG3. The present study indicates that three methods discussed here are useful for the determination of plasma clearance with 99mTc-MAG3. In addition, Bubeck's method may be preferable as a reference for single plasma sampling method because of common application to adults and children.
authors.affiliation: Department of Radiology, JR Sapporo General Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Itoh
authors.forename: E
authors.initials: E
authors.lastname: Tsukamoto
authors.forename: T
authors.initials: T
authors.lastname: Mochizuki
authors.forename: K
authors.initials: K
authors.lastname: Kanegae
authors.forename: C
authors.initials: C
authors.lastname: Katoh
authors.forename: N
authors.initials: N
authors.lastname: Tamaki
mesh_terms: D000293:Adolescent; D000328:Adult; D000465:Algorithms; D002648:Child; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011866:Radioisotope Renography / Q000379:methods*; D019275:Radiopharmaceuticals / Q000097:blood; D017263:Technetium Tc 99m Mertiatide / Q000097:blood
chemical_list: D019275:Radiopharmaceuticals; D017263:Technetium Tc 99m Mertiatide