title: Role of electron microscopy in the evaluation of soft tissue neoplasms, with emphasis on spindle cell and pleomorphic tumors.
abstract: The current significant role of transmission electron microscopy in the evaluation of soft tissue tumors when correlated with conventional histological and immunohistochemical studies is discussed for the following entities: myxofibrosarcoma, storiform-pleomorphic fibrosarcoma (malignant fibrous histiocytoma), and myofibrosarcoma; dermatofibrosarcoma protuberans; hemangiopericytoma; monophasic synovial sarcoma; extrarenal rhabdoid tumor; soft tissue perineurioma; and gastrointestinal stromal tumors, notably the so-called autonomic nerve variant.
authors.affiliation: Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Erlandson
authors.forename: J M
authors.initials: JM
authors.lastname: Woodruff
mesh_terms: D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism; D002675:Child, Preschool; D005260:Female; D005347:Fibroblasts / Q000378:metabolism / Q000648:ultrastructure; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D006393:Hemangiopericytoma / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D007120:Immunochemistry; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D018218:Neoplasms, Fibrous Tissue / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D018335:Rhabdoid Tumor / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D013584:Sarcoma, Synovial / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000648:ultrastructure*; D017154:Stromal Cells / Q000378:metabolism / Q000648:ultrastructure
chemical_list: D014408:Biomarkers, Tumor