title: Electrochemical studies of S-nitrosothiols.
abstract: S-nitrosothiols (RSNO), such as SNAP, GSNO, and Glc-SNAP-1 exhibited a single, totally irreversible, diffusion controlled reduction peak at potentials of -0.97 V, -0.98 V and -0.91 V, respectively, vs. Ag/AgCl (3 M NaCl) reference electrode. This corresponded to the nitric oxide (NO) release from the S-nitrosothiols. A possible mechanism is proposed for the reduction process.
authors.affiliation: Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Hou
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.forename: F
authors.initials: F
authors.lastname: Arias
authors.forename: L
authors.initials: L
authors.lastname: Echegoyen
authors.forename: P G
authors.initials: PG
authors.lastname: Wang
mesh_terms: D004563:Electrochemistry; D005978:Glutathione / Q000031:analogs & derivatives* / Q000737:chemistry; D008623:Mercaptoethanol; D009603:Nitroso Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D010396:Penicillamine / Q000031:analogs & derivatives* / Q000737:chemistry; D026422:S-Nitrosoglutathione; D026403:S-Nitrosothiols
chemical_list: D009603:Nitroso Compounds; D026403:S-Nitrosothiols; C110881:S-nitro-N-acetylpenicillamine; D026422:S-Nitrosoglutathione; D008623:Mercaptoethanol; C032635:S-nitrosomercaptoethanol; D005978:Glutathione; D010396:Penicillamine