Significance of tissue polypeptide specific antigen (TPS) in diagnosis and monitoring of treatment in ovarian cancer.
Tissue polypeptide specific antigen (TPS) finds increasingly broad application in diagnosis and monitoring of treatment in ovarian cancer. Its sensitivity increases in parallel to clinical advancement of the tumor and to the grade of cellular differentiation. TPS may represent valuable supplementation of conventional markers in diagnosis of mucous carcinoma. Improved sensitivity and specificity of the technique for detection of ovarian cancer occur when two or more additional tumour markers are used in parallel. TPS has been found to represent a dependable index of surgical completeness. Determination of TPS in the sera of patients with ovarian cancer in the course of chemical treatment provides important information on the course of the neoplastic process and defines the response of the host to the applied treatment.
Zygmunt
A
A
Department of Obstetrics and Gynecology, Saint Family Hospital, Poznan, Poland.
Markowska
J
J
Fischer
N
N
D014408:Biomarkers, Tumor / Q000097:blood*; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods; D008991:Monitoring, Physiologic / Q000379:methods; D010051:Ovarian Neoplasms / Q000097:blood / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D019396:Tissue Polypeptide Antigen / Q000032:analysis / Q000097:blood*
D014408:Biomarkers, Tumor; D019396:Tissue Polypeptide Antigen