Inhibition of Borna disease virus replication by ribavirin in persistently infected cells.
Ribavirin at concentrations from 1 to 10 micrograms/ml exhibited inhibitory effects on transcription of Borna disease virus (BDV) in persistently infected cells. Our present study indicates that ribavirin is a candidate anti-BDV drug.
Mizutani
T
T
Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Inagaki
H
H
Araki
K
K
Kariwa
H
H
Arikawa
J
J
Takashima
I
I
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D001891:Borna disease virus / Q000187:drug effects* / Q000502:physiology; D002460:Cell Line; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D008297:Male; D012254:Ribavirin / Q000494:pharmacology*; D014779:Virus Replication / Q000187:drug effects
D000998:Antiviral Agents; D012254:Ribavirin