Acute disseminated encephalomyelitis after accidental injection of a hog vaccine: successful treatment with plasmapheresis.
Acute disseminated encephalomyelitis, an inflammatory demyelinating disease of the central nervous system, can occur after viral infections or vaccinations. We report the clinical and neuroimaging findings in a 52-year-old man in whom acute disseminated encephalomyelitis developed after accidental self-injection of an industrial hog vaccine. The protracted and progressive clinical course, despite high-dose parenteral corticosteroid therapy, was altered by aggressive plasmapheresis.
Dodick
D W
DW
Department of Neurology, Mayo Clinic Scottsdale, AZ 85259, USA.
Silber
M H
MH
Noseworthy
J H
JH
Wilbright
W A
WA
Rodriguez
M
M
D000062:Accidents, Occupational; D000818:Animals; D001428:Bacterial Vaccines / Q000009:adverse effects; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007267:Injections; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis; D013552:Swine; D017778:Vaccines, Combined / Q000009:adverse effects*; D014765:Viral Vaccines / Q000009:adverse effects
D001428:Bacterial Vaccines; D017778:Vaccines, Combined; D014765:Viral Vaccines