title: Embryonal rhabdomyosarcoma of the nose in an elderly patient, case report and review of the literature.
abstract: Embryonal rhabdomyosarcoma of the head and neck is very rare in adults. We report on an embryonal rhabdomyosarcoma of the nose, occuring in a 74-year-old female patient presenting with nasal congestion as the only clinical symptom. Suspected to be an amelanotic melanoma, further biopsies and histological examinations provided the correct diagnosis. She first underwent a course of chemotherapy which led to a partial shrinkage of the tumor mass which was followed by a complete resection of the residual tumor mass. Biologic behaviour of this tumor must be fully appreciated as treatment is interdisciplinary. Rhabdomyosarcoma should be considered in the differential diagnosis of tumors of the nose and paranasal sinuses not only in children, but also in adults.
authors.affiliation: Department of ENT, Head and Neck Surgery, Ludwig-Maximilians-Universität München, Klinikum Grosshadern, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Jund
authors.forename: A
authors.initials: A
authors.lastname: Leunig
authors.forename: H
authors.initials: H
authors.lastname: Hagedorn
authors.forename: A
authors.initials: A
authors.lastname: Nerlich
authors.forename: G
authors.initials: G
authors.lastname: Grevers
mesh_terms: D017677:Age Distribution; D000368:Aged; D001706:Biopsy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009669:Nose Neoplasms / Q000473:pathology* / Q000628:therapy; D018233:Rhabdomyosarcoma, Embryonal / Q000473:pathology* / Q000628:therapy; D014057:Tomography, X-Ray Computed