[Change in urea-forming function of rat liver in the acute and recovery period after radiation exposure].
The results of investigations of some metabolites and enzymes of ornithine cycle in total gamma-irradiated rats are presented. It is shown that ionizing radiation furthers the intensification of liver ammonium binding function. It took place without visible enzyme activation during the first period of defeat. The increasing of enzyme activity at the top of pathological process development is also shown. The definite dose-dependence was observed in this period. The month after irradiation the liver function was decreased and during two month after influence the liver function was not normal.
Mardashko
A A
AA
Odessa State Medical University, Ukraine.
Dikhtiaruk
I I
II
D000208:Acute Disease; D000818:Animals; D005260:Female; D008099:Liver / Q000378:metabolism* / Q000503:physiopathology; D009952:Ornithine / Q000378:metabolism; D000644:Quaternary Ammonium Compounds / Q000378:metabolism; D011833:Radiation Injuries, Experimental / Q000378:metabolism* / Q000503:physiopathology; D051381:Rats; D017208:Rats, Wistar; D014508:Urea / Q000378:metabolism*
D000644:Quaternary Ammonium Compounds; D014508:Urea; D009952:Ornithine
Izmenenie mochevinoobrazovatel'noĭ funktsii pechenii krys v ostrom i vosstanovitel'nom periode posle radiatsionnogo vozdeĭstviia.