title: Acute disseminated encephalomyelitis after accidental injection of a hog vaccine: successful treatment with plasmapheresis.
abstract: Acute disseminated encephalomyelitis, an inflammatory demyelinating disease of the central nervous system, can occur after viral infections or vaccinations. We report the clinical and neuroimaging findings in a 52-year-old man in whom acute disseminated encephalomyelitis developed after accidental self-injection of an industrial hog vaccine. The protracted and progressive clinical course, despite high-dose parenteral corticosteroid therapy, was altered by aggressive plasmapheresis.
authors.affiliation: Department of Neurology, Mayo Clinic Scottsdale, AZ 85259, USA.
authors.forename: D W
authors.initials: DW
authors.lastname: Dodick
authors.forename: M H
authors.initials: MH
authors.lastname: Silber
authors.forename: J H
authors.initials: JH
authors.lastname: Noseworthy
authors.forename: W A
authors.initials: WA
authors.lastname: Wilbright
authors.forename: M
authors.initials: M
authors.lastname: Rodriguez
mesh_terms: D000062:Accidents, Occupational; D000818:Animals; D001428:Bacterial Vaccines / Q000009:adverse effects; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007267:Injections; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis; D013552:Swine; D017778:Vaccines, Combined / Q000009:adverse effects*; D014765:Viral Vaccines / Q000009:adverse effects
chemical_list: D001428:Bacterial Vaccines; D017778:Vaccines, Combined; D014765:Viral Vaccines