title: Characterization of a hypermutable strain of Drosophila simulans.
abstract: A hypermutable strain of Drosophila simulans that originated from a single spontaneous mutant male was characterized. Seven different mutations were isolated from roughly 100 generations of offspring. The genetic analysis of the viable mutants showed two mutations on the X chromosome, one in the lozenge locus and the other in the ruby gene. The autosomic mutations characterized were a dpp-heldout-like, a blistered-like and a homoeotic dominant mutant with an antenna-to-leg transformation and ectopic eyes that we called Zoinho-napata.
authors.affiliation: Departamento de Biologia, Universidade Federal de Santa Maria, RS, Brazil.
authors.forename: E L
authors.initials: EL
authors.lastname: Loreto
authors.forename: A
authors.initials: A
authors.lastname: Zaha
authors.forename: C
authors.initials: C
authors.lastname: Nichols
authors.forename: J A
authors.initials: JA
authors.lastname: Pollock
authors.forename: V L
authors.initials: VL
authors.lastname: Valente
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004330:Drosophila / Q000235:genetics*; D005124:Eye Abnormalities / Q000235:genetics*; D017344:Genes, Insect / Q000235:genetics*; D008855:Microscopy, Electron, Scanning; D009154:Mutation / Q000235:genetics*; D010641:Phenotype; D013909:Thorax / Q000002:abnormalities; D014921:Wings, Animal / Q000002:abnormalities