title: Regulation of polar auxin transport by AtPIN1 in Arabidopsis vascular tissue.
abstract: Polar auxin transport controls multiple developmental processes in plants, including the formation of vascular tissue. Mutations affecting the PIN-FORMED (PIN1) gene diminish polar auxin transport in Arabidopsis thaliana inflorescence axes. The AtPIN1gene was found to encode a 67-kilodalton protein with similarity to bacterial and eukaryotic carrier proteins, and the AtPIN1 protein was detected at the basal end of auxin transport-competent cells in vascular tissue. AtPIN1 may act as a transmembrane component of the auxin efflux carrier.
authors.affiliation: Max-Delbrück-Laboratorium in der Max-Planck-Gesellschaft, Carl-von-Linné-Weg 10, D-50829 Köln, Germany.
authors.forename: L
authors.initials: L
authors.lastname: Gälweiler
authors.forename: C
authors.initials: C
authors.lastname: Guan
authors.forename: A
authors.initials: A
authors.lastname: Müller
authors.forename: E
authors.initials: E
authors.lastname: Wisman
authors.forename: K
authors.initials: K
authors.lastname: Mendgen
authors.forename: A
authors.initials: A
authors.lastname: Yephremov
authors.forename: K
authors.initials: K
authors.lastname: Palme
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000737:chemistry / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D029681:Arabidopsis Proteins; D001692:Biological Transport / Q000187:drug effects; D015152:Blotting, Northern; D003001:Cloning, Molecular; D020451:Contig Mapping; D004251:DNA Transposable Elements; D017343:Genes, Plant; D007210:Indoleacetic Acids / Q000378:metabolism*; D008565:Membrane Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D026901:Membrane Transport Proteins; D008969:Molecular Sequence Data; D016254:Mutagenesis, Insertional; D010641:Phenotype; D010797:Phthalimides / Q000494:pharmacology; D018517:Plant Roots / Q000378:metabolism; D018547:Plant Stems / Q000378:metabolism; D018892:Proton-Motive Force
chemical_list: D029681:Arabidopsis Proteins; D004251:DNA Transposable Elements; D007210:Indoleacetic Acids; D008565:Membrane Proteins; D026901:Membrane Transport Proteins; C116363:PIN1 protein, Arabidopsis; D010797:Phthalimides; C002687:alpha-naphthylphthalamic acid