Heme oxygenase inhibits nitric oxide synthase by degrading heme: a negative feedback regulation mechanism for nitric oxide production.
Turcanu
V
V
Department of Immunopharmacology, University Louis Pasteur, Strasbourg, France.
Dhouib
M
M
Poindron
P
P
D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology / Q000502:physiology; D004790:Enzyme Induction; D005246:Feedback; D006418:Heme / Q000378:metabolism*; D006419:Heme Oxygenase (Decyclizing) / Q000096:biosynthesis / Q000378:metabolism*; D006427:Hemin / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000494:pharmacology; D008089:Listeria monocytogenes; D008264:Macrophages / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D019001:Nitric Oxide Synthase / Q000096:biosynthesis*; D012475:Salmonella / Q000276:immunology
D008070:Lipopolysaccharides; D006418:Heme; D006427:Hemin; D019001:Nitric Oxide Synthase; D006419:Heme Oxygenase (Decyclizing)