title: [Effective splenectomy in a patient with HIV-associated thrombocytopenia].
abstract: A 31-year-old man presented with a 3-month history of petechial hemorrhages. Physical examination revealed no splenomegaly. The patient's platelet count was 1.0 x 10(9)/l and bone marrow aspiration showed an elevated number of megakaryocytes. A diagnosis of HIV-associated thrombocytopenia was made on the basis of HIV seropositive results. The CD4 cell count was 400 x 10(6)/l. No opportunistic infections indicating AIDS were detected. Initially the patient was treated with predonisolone, but showed only a transient response. He also failed to respond to zidovudine, lamivudine, or indinavir. Following splenectomy, however, his platelet count rose above 80 x 10(9)/l (normal level: 150-350 x 10(9)/l).
authors.affiliation: Department of Internal Medicine, Tokyo Metropolitan Bokuto General Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Kato
authors.forename: K
authors.initials: K
authors.lastname: Nakamura
authors.forename: K
authors.initials: K
authors.lastname: Haraguchi
authors.forename: A
authors.initials: A
authors.lastname: Ajima
authors.forename: H
authors.initials: H
authors.lastname: Fujita
authors.forename: J
authors.initials: J
authors.lastname: Tomiyama
authors.forename: H
authors.initials: H
authors.lastname: Kudo
authors.forename: Y
authors.initials: Y
authors.lastname: Onozawa
authors.forename: K
authors.initials: K
authors.lastname: Ohnishi
authors.forename: N
authors.initials: N
authors.lastname: Umekita
mesh_terms: D000328:Adult; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D013156:Splenectomy; D013921:Thrombocytopenia / Q000601:surgery*