Periodontal attachment loss in patients after head and neck radiation therapy.
OBJECTIVE
The purpose of this study was to determine the potential impact of head and neck radiation therapy on the progression of periodontal attachment loss.


METHODS
Ten patients who received unilateral radiation fields that included the dentition were assessed before radiation treatment and after irradiation at a mean age of 6.01 years. Complete oral, dental, and periodontal examinations were completed by one examiner. The results were assessed through use of paired t tests.


RESULTS
More teeth were extracted because of periodontal disease in the field of radiation after irradiation. Remaining teeth in the radiated volume showed an increase in probing depth of 0.82 mm in comparison with 0.40 mm for teeth in the nonradiated region (P = .05). Recession on the facial aspects was 1.88 mm for teeth in the radiated volume and 1.16 mm for teeth in the nonradiated region (P = .001), and recession on the lingual aspects was 2.10 for teeth in the radiated volume and 0.91 for teeth in the nonradiated region (P = .05). Mean total attachment loss was 2.81 mm for teeth in the radiated sites; this compared with 1.43 mm for teeth in the nonradiated sites (P = .003). Increased mobility of teeth in the high-dose fields was seen (P = .02).


CONCLUSIONS
This study showed that tooth loss and greater periodontal attachment loss occur in teeth that are included within high-dose radiated sites of patients treated with irradiation therapy for cancer. These findings should be considered in preradiation treatment planning.
Epstein
J B
JB
British Columbia Cancer Agency, Vancouver, Canada.
Lunn
R
R
Le
N
N
Stevenson-Moore
P
P
D000328:Adult; D000368:Aged; D018267:Carcinoma, Acinar Cell / Q000532:radiotherapy; D003528:Carcinoma, Adenoid Cystic / Q000532:radiotherapy; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D016371:Cranial Irradiation / Q000009:adverse effects*; D005260:Female; D005889:Gingival Recession / Q000209:etiology; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D017622:Periodontal Attachment Loss / Q000209:etiology*; D011879:Radiotherapy Dosage; D018709:Statistics, Nonparametric; D016388:Tooth Loss / Q000209:etiology; D014086:Tooth Mobility / Q000209:etiology