title: Validation of the hypomania interview guide-seasonal affective disorder (HIGH-SAD) version in patients with rapid cycling bipolar disorder.
abstract: We validated the Hypomania Interview Guide-Seasonal Affective Disorder version (HIGH-SAD) in patients with rapid cycling bipolar disorder (RCBD). Fourteen outpatients were rated on six separate occasions (total = 84 visits). On each visit the patients were rated with the HIGH-SAD and the Young Mania Rating Scale (YMRS) in a counterbalanced order. Clinical assessment was completed at the end of the visit by the treating psychiatrist. Patients were assessed as hypomanic/manic on 22 of the visits. Pearson correlation coefficient between the YMRS total scores and the HIGH-SAD total scores for those 22 visits in which patients were hypomanic/manic was r = 0.629 (P < 0.05) and for all visits was r = 0.769 (P < 0.0001). Analysis with only one rating per patient yielded a Pearson correlation coefficient of r = 0.792 (P < 0.0004). We found that the HIGH-SAD was a valid scale for the measurement of hypomania in patients with RCBD. However, the scale does not differentiate hypomania from mania in this group of patients.
authors.affiliation: Clinical Psychobiology Branch, National Institute of Mental Health, Bethesda, Maryland 20892-1255, USA.
authors.forename: S
authors.initials: S
authors.lastname: Feldman-Naim
authors.forename: C H
authors.initials: CH
authors.lastname: Lowe
authors.forename: F S
authors.initials: FS
authors.lastname: Myers
authors.forename: E H
authors.initials: EH
authors.lastname: Turner
authors.forename: L M
authors.initials: LM
authors.lastname: Weinstock
authors.forename: E
authors.initials: E
authors.lastname: Leibenluft
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D015203:Reproducibility of Results; D016574:Seasonal Affective Disorder / Q000175:diagnosis* / Q000523:psychology; D012720:Severity of Illness Index