title: Standardization activities of markers of cardiac damage: the need of a comprehensive approach.
abstract: The field of biochemical markers of cardiac damage is in a dynamic state, with new applications continually appearing and new assays and markers being developed, but also with several analytical and interpretative problems to resolve. In this situation it is essential that a uniform and rigorous outlook be maintained to ensure optimal test utilization. For these reasons, the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) agreed to establish a Committee on 'Standardization of Markers of Cardiac Damage' (C-SMCD). The first task of the C-SMCD concerns coordination of the different activities from affiliated associations, with (1) a review of documents and recommendations and (2) supervision and, possibly, the take-over of the standardization activities. Second, the C-SMCD supports development of scientific programmes for forthcoming international meetings and congresses. The third task of the C-SMCD is development of specific additional projects to promote the rational use of cardiac markers and to identify new areas of research.
authors.affiliation: 1st Laboratory of Clinical Chemistry, Spedali Civili, Brescia, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Panteghini
mesh_terms: D015415:Biomarkers / Q000097:blood; D019963:Clinical Chemistry Tests / Q000592:standards*; D003327:Coronary Disease / Q000175:diagnosis*; D003402:Creatine Kinase / Q000097:blood; D006801:Humans; D007527:Isoenzymes; D009206:Myocardium / Q000201:enzymology; D012016:Reference Values; D020107:Troponin T / Q000097:blood
chemical_list: D015415:Biomarkers; D007527:Isoenzymes; D020107:Troponin T; D003402:Creatine Kinase