title: Respiratory bronchiolitis: radiographic and CT findings in a pathologically proven case.
abstract: A small number of cases of cigarette-smoking-associated respiratory bronchiolitis (RB) with positive findings on the chest radiograph have been reported in the literature. High-resolution computed tomography (HRCT) findings are available in even fewer cases. We describe the case of an asymptomatic female smoker presenting with a reticulomicronodular infiltrate on a routine chest radiograph. High-resolution CT was characterized by ground-glass opacities and centrilobular micronodules with an upper lobe predominance. Surgical biopsy revealed peribronchiolar lesions, with accumulation of brown pigmented macrophages in the lumen of alveolar and bronchiolar lumen, consistent with the pathologic diagnosis of RB.
authors.affiliation: Department of Radiology, Pitié-Salpêtrière Hospital, Paris, France.
authors.forename: O
authors.initials: O
authors.lastname: Essadki
authors.forename: C
authors.initials: C
authors.lastname: Chartrand-Lefebvre
authors.forename: J
authors.initials: J
authors.lastname: Briere
authors.forename: P
authors.initials: P
authors.lastname: Grenier
mesh_terms: D000368:Aged; D001706:Biopsy; D001980:Bronchi / Q000473:pathology; D001988:Bronchiolitis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008168:Lung / Q000000981:diagnostic imaging; D016676:Macrophages, Alveolar / Q000473:pathology; D010858:Pigmentation; D013902:Radiography, Thoracic; D012907:Smoking / Q000009:adverse effects; D014057:Tomography, X-Ray Computed