[Effect of Arnica montana on the state of lipid peroxidation and protective glutathione system of rat liver in experimental toxic hepatitis].
Effects of Tinctura Arnica on lipids peroxidation and on the protective glutathions system of liver in rats in case of experimental toxic hepatitis have been studied. Toxic hepatitis is accompanied by deep alterations of the oxidant-antioxidant status of the body. Intoxication of the body by CCl4 results in intensification of the free radicals formation particularly in liver: accumulation of lipids peroxidation molecular products, glutathione system enzyme activity inhibition in early terms and its partial restoration in remote terms has been seen. Our studies revealed that Arnica montana infusion inhibits the rate of lipids perioxidation products formation, affects the glutathione system enzymes activity.
Iamemiĭ
I M
IM
Bukovinien State Medical Academy, Chernivtsi.
Grygor'iea
N P
NP
Meshchyshen
I F
IF
D000818:Animals; D018650:Arnica / Q000737:chemistry*; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology / Q000378:metabolism*; D005978:Glutathione / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats
D010936:Plant Extracts; D005978:Glutathione
Vplyv nastoĭky arniky hirs'koï na stan peroksydnoho okylenennia lipidiv ta zakhysnoï glutationovoï systemy pechinky shchuriv za umov eksperiymental'noho toksichnoho hepatytu.