Ticlopidine-induced thrombotic thrombocytopenic purpura.
Thrombotic thrombocytopenic purpura (TTP) occurs in association with a wide variety of disorders including infections, connective tissue diseases, and solid organ tumors. It also may coincide with administration of drugs such as mitomycin, metronidazole, oral contraceptives, cyclosporine, and many others. We report the occurrence of TTP in a patient shortly after the initiation of ticlopidine.
Muszkat
M
M
Division of Medicine, Hadassah University Hospital, Jerusalem, Israel.
Shapira
M Y
MY
Sviri
S
S
Linton
D M
DM
Caraco
Y
Y
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011697:Purpura, Thrombotic Thrombocytopenic / Q000139:chemically induced*; D013988:Ticlopidine / Q000009:adverse effects*
D005343:Fibrinolytic Agents; D013988:Ticlopidine