Constituents and bioactive principles of Polygonum chinensis.
Isolation and characterization of the chemical constituents of Polygonum chinensis L. gave the new 25R-spirost-4-ene-3,12-dione. The known compounds stigmast-4-ene-3,6-dione, stigmastane-3,6-dione, hecogenin and aurantiamide acetate were also isolated from for the first time from this species. Their anti-inflammatory and anti-allergic properties are described.
Tsai
P L
PL
Graduate Institute of Pharmaceutical Chemistry, China Medical College, Taichung, Taiwan, R.O.C.
Wang
J P
JP
Chang
C W
CW
Kuo
S C
SC
Chao
P D
PD
D000818:Animals; D018926:Anti-Allergic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002783:Cholestenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004151:Dipeptides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008407:Mast Cells / Q000187:drug effects; D015394:Molecular Structure; D010946:Plants, Medicinal; D051381:Rats; D017207:Rats, Sprague-Dawley; D012502:Sapogenins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013057:Spectrum Analysis; D013150:Spirostans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
C116554:25-spirost-4-ene-3,12-dione; D018926:Anti-Allergic Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D002783:Cholestenones; D004151:Dipeptides; D012502:Sapogenins; D013150:Spirostans; C017726:stigmast-4-ene-3,6-dione; C007908:hecogenin; C011670:N-benzoylphenylalanylphenylalinol acetate