title: 1st MRC Human Genetics Symposium: maintenance of genomic stability.
abstract: This meeting served to juxtapose the fundamental studies on the distinct pathways which maintain genomic stability with work that addresses the phenotypic consequences of loss of genomic stability in humans. This created an exciting environment where we were prompted to think about the links between fundamental and applied research. It was also a forum where new ideas could be formed that will hopefully fuel interesting research in human disease. As we place the genome projects into perspective, the ideas arising from meetings such as the 1st MRC Human Genetics Symposium might be expected to guide studies that will reveal the molecular defects which underlie some of the more impenetrable phenotypes of human diseases.
authors.affiliation: MRC Cell Mutation Unit, Sussex University, Falmer, Brighton, UK. a.m.carr@sussex.ac.uk
authors.forename: A M
authors.initials: AM
authors.lastname: Carr
authors.forename: E M
authors.initials: EM
authors.lastname: Taylor
mesh_terms: D000818:Animals; D002875:Chromosomes / Q000502:physiology*; D004249:DNA Damage / Q000502:physiology; D005600:Fragile X Syndrome / Q000235:genetics; D005826:Genetics, Medical; D006801:Humans; D008938:Mitosis / Q000235:genetics; D009369:Neoplasms / Q000235:genetics; D019098:Telomerase / Q000502:physiology; D016615:Telomere / Q000502:physiology
chemical_list: D019098:Telomerase