[Study of mechanisms of action of amitriptyline and acupuncture using nociceptive flexor reflex in patients with chronic forms of headache].
The nociceptive flexor reflex (NFR, R3) was tried for quantitative assessment of pain in patients with various forms of primary and secondary headaches. Amitriptyline and acupuncture elevated the threshold of R3-reflex emergence, though the threshold of subjective pain sensitivity increased only in response to amitriptyline. NFR is adequate for assessing anesthesia efficacy and investigating the mechanisms of action of analgesics in patients with headache.
Amelin
A V
AV
Zaĭtsev
A A
AA
Ivanov
V E
VE
Ignatov
Iu D
IuD
Korenko
L A
LA
Skoromets
A A
AA
D015667:Acupuncture Analgesia; D000328:Adult; D000639:Amitriptyline / Q000494:pharmacology* / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000494:pharmacology* / Q000627:therapeutic use; D002908:Chronic Disease; D005260:Female; D006261:Headache / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009619:Nociceptors / Q000187:drug effects / Q000502:physiology* / Q000503:physiopathology; D010147:Pain Measurement; D012018:Reflex / Q000187:drug effects / Q000502:physiology*; D013497:Sural Nerve / Q000502:physiology
D000929:Antidepressive Agents, Tricyclic; D000639:Amitriptyline
Izuchenie mekhanizmov deĭstviia amitriptilina i akupunktury s pomoshch'iu notsitseptivnogo sgibatel'nogo refleksa u patsientov s khronicheskimi formami golovnykh boleĭ.