title: Evaluation of gastroesophageal reflux in patients with laryngotracheal stenosis.
abstract: To report the incidence of pharyngeal acid reflux events in patients with laryngotracheal stenosis (LTS), we studied 12 patients with LTS and 34 healthy volunteers. All patients and controls underwent ambulatory 24-hour 3-site pH monitoring. In ambulatory pH monitoring, pH was recorded at manometrically determined sites of the pharynx, proximal esophagus, and distal esophagus. For all 3 sites, a pH value below 4 that was not related to the time of oral intake or belching was considered an acid reflux event. Eight of the 12 LTS patients exhibited pharyngeal acid reflux events. In the control group, pharyngeal acid reflux events were documented in 7 subjects. In between-group comparison, the number of reflux episodes and the percent acid exposure time in the pharynx were greater in LTS patients than in controls. Reflux parameters of the proximal and distal esophagus in LTS patients were similar to those of controls. The incidence of pharyngeal acid reflux events in LTS patients was higher than that in controls. It is suggested that identification and treatment of gastroesophageal reflux in patients will significantly simplify and improve the results of treatment for LTS.
authors.affiliation: Medical College of Wisconsin Dysphagia Institute, Department of Otolaryngology and Communication Sciences, The Medical College of Wisconsin, Milwaukee, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Toohill
authors.forename: S O
authors.initials: SO
authors.lastname: Ulualp
authors.forename: R
authors.initials: R
authors.lastname: Shaker
mesh_terms: D000328:Adult; D000368:Aged; D004947:Esophagus / Q000378:metabolism; D005260:Female; D005764:Gastroesophageal Reflux / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007829:Laryngostenosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D010614:Pharynx / Q000378:metabolism; D014135:Tracheal Stenosis / Q000150:complications*