title: Acute ascending aortic dissection complicating open heart surgery: cerebral perfusion defines the outcome.
abstract: OBJECTIVE
  This retrospective study was designed to assess the risks of acute ascending aorta dissection (AAD) as a rare but potentially fatal complication of open heart surgery.
  
  
  METHODS
  Among 8624 cardiac surgical procedures under cardiopulmonary bypass (CPB) and cardioplegic myocardial protection from 1978 to 1997, 10 patients (0.12%) presented with a secondary or so called 'iatrogenic' AAD. There were seven men and three women, mean age 64 +/- 9 years, ranging from 47 to 79. The original procedures involved five coronary artery bypass grafts (CABG), one repeat CABG, one aortic valve replacement (AVR), one AVR and CABG, one mitral valvuloplasty (MVP) and CABG and one ascending aorta replacement. We retrospectively analyzed their hospital records.
  
  
  RESULTS
  Group I consisted of seven patients with AAD intraoperatively and group II consisted of three patients who developed acute AAD 8-32 days after cardiac surgery. In group I, treatment consisted of the original procedure, plus grafting of the ascending aorta in six patients and closed plication and aortic wrapping in one. In group II, two patients received a dacron graft and one patient developed lethal tamponnade due to aortic rupture before surgery. Postoperatively, six patients responded well and three died (33%), two patients from group I on the 2nd postoperative day with severe post-anoxic encephalopathy, and one from group II with severe peroperative cardiogenic shock.
  
  
  CONCLUSIONS
  Preventing AAD with the appropriate means remains standard practice in cardiac surgery. If AAD occurs, it requires prompt diagnosis and interposition graft to allow a better prognosis. Intraoperative AAD happens at the beginning of CPB jeopardizing perfusion of the supra-aortic arteries.
authors.affiliation: Department of Cardiovascular Surgery, University Hospital Center, Lausanne, Switzerland. patrick.ruchat@chuv.hospvd.ch
authors.forename: P
authors.initials: P
authors.lastname: Ruchat
authors.forename: M
authors.initials: M
authors.lastname: Hurni
authors.forename: F
authors.initials: F
authors.lastname: Stumpe
authors.forename: A P
authors.initials: AP
authors.lastname: Fischer
authors.forename: L K
authors.initials: LK
authors.lastname: von Segesser
mesh_terms: D000208:Acute Disease; D000368:Aged; D000784:Aortic Dissection / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery; D001011:Aorta / Q000293:injuries / Q000601:surgery; D001014:Aortic Aneurysm / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery; D019917:Blood Vessel Prosthesis Implantation; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D016022:Case-Control Studies; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006324:Heart Arrest, Induced; D006801:Humans; D007430:Intraoperative Care; D007431:Intraoperative Complications / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D010477:Perfusion; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D016896:Treatment Outcome