title: Nitrogen-carbon-linked (azolylphenyl)oxazolidinones with potent antibacterial activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis.
authors.affiliation: Pharmacia & Upjohn, Inc., Kalamazoo, Michigan 49001, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Genin
authors.forename: D K
authors.initials: DK
authors.lastname: Hutchinson
authors.forename: D A
authors.initials: DA
authors.lastname: Allwine
authors.forename: J B
authors.initials: JB
authors.lastname: Hester
authors.forename: D E
authors.initials: DE
authors.lastname: Emmert
authors.forename: S A
authors.initials: SA
authors.lastname: Garmon
authors.forename: C W
authors.initials: CW
authors.lastname: Ford
authors.forename: G E
authors.initials: GE
authors.lastname: Zurenko
authors.forename: J C
authors.initials: JC
authors.lastname: Hamel
authors.forename: R D
authors.initials: RD
authors.lastname: Schaadt
authors.forename: D
authors.initials: D
authors.lastname: Stapert
authors.forename: B H
authors.initials: BH
authors.lastname: Yagi
authors.forename: J M
authors.initials: JM
authors.lastname: Friis
authors.forename: E M
authors.initials: EM
authors.lastname: Shobe
authors.forename: W J
authors.initials: WJ
authors.lastname: Adams
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology; D015169:Colony Count, Microbial; D006193:Haemophilus influenzae / Q000187:drug effects*; D020128:Inhibitory Concentration 50; D007275:Injections, Intravenous; D008297:Male; D051379:Mice; D001936:Moraxella catarrhalis / Q000187:drug effects*; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013203:Staphylococcal Infections / Q000188:drug therapy; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D010080:Oxazoles; C116533:PNU 171933; C116534:PNU 172576; D011720:Pyrazoles; D011758:Pyrroles