title: Metastatic intracavitary cardiac aortic body tumor in a dog.
abstract: A mobile right-ventricular mass dynamically occluding the right ostium atrioventriculare in the systolic phase was detected in a 3-year-old male Tosa dog by echocardiography. At necropsy, multiple tumor masses of various sizes were observed in the heart base right ventricular lumen, myocardium, lung and liver. Dysplasia of tricuspid valve characterized by irregular shape of leaflets, upward malposition of large papillary muscles, and shortened and stout chordae tendineae was also detected. Histopathologically, the tumor cells, arranged in sheets or nests, were polyhedral with lightly eosinophilic and finely granular cytoplasm, and contained a hyperchromatic round or oval nucleus. By Grimelius' silver stain, tumor cells had cytoplasmic positive granules. Ultrastructurally, tumor cells contained characteristic small membrane-limited granules. This is the first report of metastatic intracavitary cardiac aortic body tumor in a dog.
authors.affiliation: Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
authors.forename: K O
authors.initials: KO
authors.lastname: Cho
authors.forename: N Y
authors.initials: NY
authors.lastname: Park
authors.forename: I C
authors.initials: IC
authors.lastname: Park
authors.forename: B K
authors.initials: BK
authors.lastname: Kang
authors.forename: M
authors.initials: M
authors.lastname: Onuma
mesh_terms: D000818:Animals; D002345:Carotid Body Tumor / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D004452:Echocardiography; D017809:Fatal Outcome; D006338:Heart Neoplasms / Q000556:secondary / Q000662:veterinary*; D008297:Male; D009206:Myocardium / Q000473:pathology; D014261:Tricuspid Valve / Q000473:pathology