title: Acute onset of coagulopathy in a patient with Kasabach-Merritt syndrome following transurethral resection of bladder tumor.
abstract: We report an unusual case of Kasabach-Merritt syndrome in a 62 year-old woman with bladder tumor who suffered from acute consumption coagulopathy that increased the fibrinolytic activity due to the presence of a huge hemangioma in the upper and lower extremities. Two days after the transurethral resection of the solitary bladder tumor, serious hematuria and life-threatening disseminated intravascular coagulation developed. Following treatments with heparin and subsequent steroid treatment, hemorrhage and abnormal hemostatic values improved. It is suggested that extensive investigation of the coagulation system should be done in patients with giant hemangioma, particularly before a surgical procedure.
authors.affiliation: Department of Urology, Yamagata University School of Medicine, Yamagata, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Shoji
authors.forename: T
authors.initials: T
authors.lastname: Nakada
authors.forename: O
authors.initials: O
authors.lastname: Sugano
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: I
authors.initials: I
authors.lastname: Sasagawa
mesh_terms: D000208:Acute Disease; D000925:Anticoagulants / Q000627:therapeutic use; D001777:Blood Coagulation; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D015653:Cystectomy / Q000009:adverse effects* / Q000379:methods; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D004359:Drug Therapy, Combination; D004564:Electrocoagulation / Q000009:adverse effects / Q000379:methods; D004724:Endoscopy / Q000009:adverse effects*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006391:Hemangioma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D012983:Soft Tissue Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D013577:Syndrome; D014521:Urethra; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*
chemical_list: D000925:Anticoagulants; D005938:Glucocorticoids