[Inhibitive effect of umbellatus polyporus polysaccharide on cachexic manifestation induced by toxohormone-L in rats].
OBJECTIVE
To investigate the effect of treatment of cachexia with Umbellatus Polyporus Polysaccharide (UPP).


METHODS
UPP was used to treat cachexia induced by toxohormone-L.


RESULTS
Toxohormone-L from ascites fluid with primary hepatoma could induce lipolysis in vitro significantly, inhibit the intake behavior, decrease the level of blood zinc, increase that of blood copper (P < 0.01), upp could inhibit these effects.


CONCLUSIONS
Toxohormone-L was closely related with neoplastic cachexia and UPP could inhibit this effect induced by toxohormone-L significantly.
Wu
G S
GS
Shenyang Medical College.
Zhang
L Y
LY
Okuda
H
H
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002100:Cachexia / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy*; D003300:Copper / Q000097:blood; D004731:Endotoxins; D008066:Lipolysis / Q000187:drug effects; D008297:Male; D009363:Neoplasm Proteins; D011124:Polyporaceae / Q000737:chemistry; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D015032:Zinc / Q000097:blood
D001786:Blood Glucose; D004731:Endotoxins; D009363:Neoplasm Proteins; D011134:Polysaccharides; D003300:Copper; C010355:toxohormone; D015032:Zinc