[Morphological characteristics of lungs in embryos and fetuses in women living in regions contaminated with radionuclides after accident at the Chernobyl power plant].
The possibility of transplacental passage of Cr-90 and Cs-137 as well as their traces appearance in descendants muscles and bones beginning from the 2nd pregnancy trimester (and this was sometimes associated with teratogenic effects) was demonstrated on the abortion material (human embryos and fetuses) from the controlled zones of the Bryansk region. Statistically significant inhibition of the bronchial branching (according to the morphometry of the lung histological section) this indicating the disturbance of the lung prenatal morphogenesis during the "pseudoglandular" developmental stage was observed in the 1st trimester of the pregnancy in the descendants of the irradiated mothers. Lung hypoplasia was observed in some cases in the 2nd and 3rd trimesters of the pregnancy. Activation of lymphoid cells in the fetal lungs and the tendency to the enhancement in them of the ectopic erythroid hemopoiesis was revealed. These processes are considered as a reflection of the compensatory adaptive cellular reaction in the descendants respiratory organs in response to the tissue hypoxia and antigenic stimuli from the organism of the pregnant woman irradiated after the Chernobyl accident.
Romanova
L K
LK
Research Institute of Human Morphology, Moscow.
Pokrovskaia
M S
MS
Mladkovskaia
T B
TB
Kulikova
G V
GV
Volkova
E V
EV
Safronova
L A
LA
Zhorova
E S
ES
Beliaev
I K
IK
Gerasiuto
G I
GI
Sivakoba
I S
IS
D000328:Adult; D005314:Embryonic and Fetal Development / Q000528:radiation effects*; D005260:Female; D005865:Gestational Age; D006801:Humans; D008168:Lung / Q000196:embryology* / Q000473:pathology / Q000528:radiation effects; D018811:Maternal Exposure; D011210:Power Plants; D011247:Pregnancy; D018788:Radioactive Hazard Release; D014455:Ukraine
Morfologicheskaia kharakteristika legkikh émbrionov i plodov matereĭ, prozhivaiushchikh na territorii, zagriaznennoĭ radionuklidami posle avarii na Chernobyl'skoĭ AES.