title: A HhaI/BstUI polymorphism in a novel gene at human chromosome 11p15.5.
abstract: We found a HhaI/BstUI polymorphism in the 3' untranslated region of a novel gene which was localized to 11p15.5. This region is one of prominent imprinting domains and contains multiple imprinted genes, such as H19, IGF2, KVLQT1, and p57KIP2, which suggests that regional factors might contribute to the imprinting. This polymorphism will be useful in the allelic analysis of expression and methylation of the novel gene.
authors.affiliation: Department of Human Genetics, Nagasaki University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Miura
authors.forename: H
authors.initials: H
authors.lastname: Masuzaki
authors.forename: T
authors.initials: T
authors.lastname: Ishimaru
authors.forename: N
authors.initials: N
authors.lastname: Niikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Jinno
mesh_terms: D000483:Alleles; D002880:Chromosomes, Human, Pair 11; D019175:DNA Methylation; D015252:Deoxyribonucleases, Type II Site-Specific / Q000378:metabolism*; D005787:Gene Frequency; D018392:Genomic Imprinting; D006801:Humans; D011110:Polymorphism, Genetic
chemical_list: C039566:CGCG-specific type II deoxyribonucleases; D015252:Deoxyribonucleases, Type II Site-Specific; C037130:GCGC-specific type II deoxyribonucleases