[Addisonian crisis provoked by levothyroxine substitution therapy].
A women aged 36 with a positive family anamnesis for autoimmune endocrine diseases and a history of thyroid diseases, developed major complaints of general malaise, orthostatic hypotension and loss of appetite after the start of a treatment with levothyroxin because of (sub)clinical hypothyroidism. She was found to suffer from primary adrenocortical insufficiency masked by excessive use of liquorice and a lowered metabolism, but which via the suppletion with thyroid hormone had led to an addisonian crisis.
Dawson
L
L
Leids Universitair Medisch Centrum, afd. Algemene Interne Geneeskunde, Leiden.
Schaar
C G
CG
de Meijer
P H
PH
Meinders
A E
AE
D000224:Addison Disease / Q000139:chemically induced*; D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications / Q000188:drug therapy / Q000235:genetics; D004700:Endocrine System Diseases / Q000150:complications / Q000235:genetics; D005260:Female; D006035:Glycyrrhiza / Q000009:adverse effects; D020249:Hormone Replacement Therapy / Q000009:adverse effects*; D006801:Humans; D010375:Pedigree; D010946:Plants, Medicinal; D013959:Thyroid Diseases / Q000150:complications / Q000188:drug therapy; D013974:Thyroxine / Q000009:adverse effects*
D013974:Thyroxine
Addison-crisis uitgelokt door substitutietherapie met levothyroxine.