title: Design and synthesis of a biotinylated dopamine transporter ligand for the purification and labeling of dopaminergic neurons.
abstract: The design and synthesis of a new tool for labeling and purification of dopaminergic neurons is described.
authors.affiliation: Novartis Pharma Inc., Basel/Switzerland. Kaspar.Zimmermann@pharma.novartis.com
authors.forename: K
authors.initials: K
authors.lastname: Zimmermann
authors.forename: B
authors.initials: B
authors.lastname: Hengerer
mesh_terms: D000818:Animals; D001710:Biotin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism*; D002478:Cells, Cultured; D004298:Dopamine / Q000378:metabolism*; D050483:Dopamine Plasma Membrane Transport Proteins; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D008636:Mesencephalon / Q000166:cytology / Q000196:embryology / Q000378:metabolism; D009419:Nerve Tissue Proteins; D009474:Neurons / Q000166:cytology* / Q000378:metabolism; D010879:Piperazines / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D051381:Rats
chemical_list: C116736:CGP 81077; D002352:Carrier Proteins; D050483:Dopamine Plasma Membrane Transport Proteins; D008024:Ligands; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D010879:Piperazines; D001710:Biotin; D004298:Dopamine