Studies on the synthesis of naphthoquinoids.
Four derivatives of 6-oxo-3,4,4a,5-tetrahydro-3-hydroxy-2,2-dimethylnaphtho-1,2-pyran (1), known as bactericidal, bacteriostatic, fungicidal, fungistatic agents, were synthesized to investigate the effect of substituents on the aromatic ring.
Park
O S
OS
Department of Chemistry, Chungbuk National University, Cheongju, Korea.
Kim
J C
JC
D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D009285:Naphthoquinones / Q000138:chemical synthesis*; D011714:Pyrans / Q000138:chemical synthesis*; D013329:Structure-Activity Relationship; D013764:Tetrahydronaphthalenes / Q000138:chemical synthesis*
C116956:6-oxo-3,4,4a,5-tetrahydro-3-hydroxy-2,2-dimethylnaphtho-1,2-pyran; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D009285:Naphthoquinones; D011714:Pyrans; D013764:Tetrahydronaphthalenes