title: Endothelin-1 in heart failure: does it play a role?
authors.affiliation: Myocardial Biology Unit, Boston Medical Center, MA 02118, USA.
authors.forename: F
authors.initials: F
authors.lastname: Sam
authors.forename: W S
authors.initials: WS
authors.lastname: Colucci
mesh_terms: D000818:Animals; D000077300:Bosentan; D002986:Clinical Trials as Topic; D065128:Endothelin Receptor Antagonists; D019332:Endothelin-1 / Q000096:biosynthesis / Q000097:blood / Q000502:physiology*; D004730:Endothelium, Vascular / Q000378:metabolism; D006333:Heart Failure / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D051379:Mice; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy / Q000401:mortality; D009206:Myocardium / Q000378:metabolism; D010456:Peptides, Cyclic / Q000627:therapeutic use; D051381:Rats; D017466:Receptors, Endothelin / Q000502:physiology; D013318:Stroke Volume; D013449:Sulfonamides / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D065128:Endothelin Receptor Antagonists; D019332:Endothelin-1; D010456:Peptides, Cyclic; D017466:Receptors, Endothelin; D013449:Sulfonamides; D000077300:Bosentan; C072247:cyclo(Trp-Asp-Pro-Val-Leu)