title: Blood plasma levels of lipoperoxides, glutathione peroxidase, beta carotene, vitamin A and E in women with habitual abortion.
abstract: The plasma levels of lipoperoxides, glutathione peroxidase (GSH-Px), reduced glutathione (GSH), beta carotene, vitamin A, E, some plasma biochemical and blood haematological parameters were investigated in 40 women with habitual abortion (HA) and controls. The levels of GSH, vitamin A, E and beta carotene were significantly lower in women with HA than in controls. However, the plasma levels of lipid peroxidation, alkaline phosphatase (ALP), glucose and blood haemoglobin were significantly higher in HA than in controls. In addition, plasma levels of GSH-Px, AST, ALT, total bilirubin, total protein, albumin, sodium, potassium, calcium and number of white blood cells, red blood cells, platelet and values of packet cell volume showed no significant differences between HA and controls. According to the results of this study, we observed that the levels of lipid peroxidation were increased and plasma levels of vitamin A, E and beta carotene were decreased in HA. The decrease of those antioxidants may play a significant role in women with habitual abortion.
authors.affiliation: Department of Obstetrics and Gynaecology, Firat University, Medical Faculty, Elaziğ, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Simşek
authors.forename: M
authors.initials: M
authors.lastname: Naziroğlu
authors.forename: H
authors.initials: H
authors.lastname: Simşek
authors.forename: M
authors.initials: M
authors.lastname: Cay
authors.forename: M
authors.initials: M
authors.lastname: Aksakal
authors.forename: S
authors.initials: S
authors.lastname: Kumru
mesh_terms: D000026:Abortion, Habitual / Q000097:blood*; D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D004573:Electrolytes / Q000097:blood; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood*; D006801:Humans; D015227:Lipid Peroxidation; D008054:Lipid Peroxides / Q000097:blood*; D008111:Liver Function Tests; D018384:Oxidative Stress; D011247:Pregnancy; D014801:Vitamin A / Q000097:blood*; D014810:Vitamin E / Q000097:blood*; D019207:beta Carotene / Q000097:blood*
chemical_list: D004573:Electrolytes; D008054:Lipid Peroxides; D019207:beta Carotene; D014801:Vitamin A; D014810:Vitamin E; D005979:Glutathione Peroxidase; D000469:Alkaline Phosphatase