Screening and isolation of antibiotic resistance inhibitors from herb materials-resistance inhibition of volatile components of Korean aromatic herbs.
The resistance inhibitory activities of 54 odorant mixtures (essential oil) from 41 Korean aromatic herbs were tested against multi-drug resistant Staphylococcus aureus SA2, which has resistances to 10 usual antibiotics including chloramphenicol. As results, combinations of 28 kinds of samples from 21 herbs and chloramphenicol have resistance inhibitory activities in dose dependent manner.
Lee
C K
CK
College of Pharmacy, Kyungsung University, Pusan, Korea.
Kim
H
H
Moon
K H
KH
Shin
K H
KH
D002702:Chloramphenicol Resistance; D004305:Dose-Response Relationship, Drug; D004352:Drug Resistance, Microbial; D007723:Korea; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects*
D009822:Oils, Volatile