[Biochemical mechanisms of the toxic effect of oxalates].
The effect of oxalic acid and its salts on the biochemical systems of the homeostasis of white rats were investigated. It has been shown that oxalates inhibit enzymes of energy metabolism and cause the changes in parameters of nephrotoxicity, electrolyte balance of blood plasma and urine, lipid peroxidation, antiperoxidational defence system.
Khlus
K N
KN
Research Institute of Medico-ecological Problems, Ministry of Public Health of Ukraine, Chernovtsy.
D000818:Animals; D004573:Electrolytes / Q000097:blood / Q000652:urine; D004791:Enzyme Inhibitors / Q000633:toxicity; D005260:Female; D006706:Homeostasis / Q000187:drug effects; D007668:Kidney / Q000187:drug effects; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D010070:Oxalates / Q000633:toxicity*; D051381:Rats
D004573:Electrolytes; D004791:Enzyme Inhibitors; D010070:Oxalates
Biokhimicheskie mkhanizmy toksicheskogo deĭstviia oksalatov.