title: Frequency judgements of abstract designs by patients with diencephalic, temporal lobe or frontal lobe lesions.
abstract: Patients with diencephalic, temporal lobe or frontal lobe lesions were compared with healthy controls on a frequency judgement task. The three patient groups were disproportionately impaired at estimating how often a series of abstract designs had been presented relative to controls. Diencephalic and temporal lobe patients did not differ from each other. It is argued that the results may reflect a 'core' memory deficit in the temporal lobe patients. The impairment in the frontal patients may reflect their difficulty in making an organised search in memory for multiple traces of an item, while the deficit shown by the diencephalic patients (particularly those with Korsakoff syndrome) may be due to the combined effects of a generally poor memory and superimposed frontal pathology.
authors.affiliation: Psychology Department, Institute of Psychiatry, London, UK.
authors.forename: N
authors.initials: N
authors.lastname: Stanhope
authors.forename: E
authors.initials: E
authors.lastname: Guinan
authors.forename: M D
authors.initials: MD
authors.lastname: Kopelman
mesh_terms: D000328:Adult; D000368:Aged; D000425:Alcohol Amnestic Disorder / Q000175:diagnosis / Q000503:physiopathology; D001288:Attention / Q000502:physiology*; D001925:Brain Damage, Chronic / Q000175:diagnosis / Q000503:physiopathology*; D001931:Brain Mapping; D004027:Diencephalon / Q000503:physiopathology*; D004193:Discrimination Learning / Q000502:physiology*; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual / Q000502:physiology*; D011340:Problem Solving / Q000502:physiology; D013702:Temporal Lobe / Q000503:physiopathology*