title: Combinatorial chemistry of hydantoins.
abstract: Access to combinatorial chemistry of hydantoins is provided by convenient and versatile methods for the solid phase synthesis of libraries of 3,5-, 1,3- and 1,3,5-substituted hydantoins. The preparation of trisubstituted hydantoins features a Mitsunobu reaction for introduction of the substituent on N-1.
authors.affiliation: Department of Medicinal Chemistry, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, The Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: Boeijen
authors.forename: J A
authors.initials: JA
authors.lastname: Kruijtzer
authors.forename: R M
authors.initials: RM
authors.lastname: Liskamp
mesh_terms: D019992:Databases as Topic; D015195:Drug Design; D006827:Hydantoins / Q000138:chemical synthesis* / Q000737:chemistry*; D007202:Indicators and Reagents; D008968:Molecular Conformation; D015394:Molecular Structure; D013329:Structure-Activity Relationship
chemical_list: D006827:Hydantoins; D007202:Indicators and Reagents