Salmonella-S. mansoni association in patients with acquired immunodeficiency syndrome.
Two young men with Salmonella bacteraemia, active schistosomiasis and the acquired immunodeficiency syndrome are reported. The clinical presentation comprised nonspecific signs and symptoms, such as fatigue, malaise, weight loss, diarrhoea, prolonged fever, and hepatosplenomegaly. In one patient, liver biopsy showed poorly formed granulomata around Schistosoma mansoni eggs and hepatitis. Treatment of schistosomiasis alone induced consistent clinical improvement with eventual cure of both Salmonella and S. mansoni infections. Recognition of the Salmonella-S. mansoni association in patients with AIDS is important because treatment of schistosomiasis makes a difference, improving the prognosis of this otherwise, recurrent, potentially fatal bacteraemia.
Lambertucci
J R
JR
Departamento de Clínica Médica, Faculdade de Medicina de UFMG, Belo Horizonte, MG, Brasil. lamber@net.em.com.br
Rayes
A A
AA
Gerspacher-Lara
R
R
D017088:AIDS-Related Opportunistic Infections / Q000150:complications*; D000328:Adult; D006801:Humans; D008297:Male; D010073:Oxamniquine / Q000627:therapeutic use; D012480:Salmonella Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D012555:Schistosomiasis mansoni / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D012556:Schistosomicides / Q000627:therapeutic use
D012556:Schistosomicides; D010073:Oxamniquine