A highly polymorphic CA repeat marker at the human interleukin 6 receptor (IL6R) locus.
A polymorphic dinucleotide (CA) sequence was isolated from a genomic clone containing the human interleukin 6 receptor (IL6R) gene. High heterozygosity (0.81) makes this polymorphism a useful marker in the genetic study of disorders affecting the inflammation process and bone resorption.
Tsukamoto
K
K
Department of Molecular Biology, Nippon Medical School, Kawasaki, Japan.
Ohta
N
N
Shirai
Y
Y
Emi
M
M
D000483:Alleles; D001862:Bone Resorption / Q000235:genetics; D002878:Chromosomes, Human, Pair 1; D018900:Dinucleotide Repeats; D005787:Gene Frequency; D005819:Genetic Markers; D006801:Humans; D011110:Polymorphism, Genetic; D019947:Receptors, Interleukin-6 / Q000235:genetics*
D005819:Genetic Markers; D019947:Receptors, Interleukin-6