title: [Ulnar nerve palsy in leprosy without skin changes: biopsy of the superficial branch of the ulnar nerve in the hand].
abstract: Leprosy is one of the most common diseases of peripheral nerves in the world. In Brazil it is particularly frequent, being a major health problem. In tuberculoid leprosy the ulnar nerve is the most common affected nerve. Sometimes there are no skin changes. In these cases in spite of nerve thickening only the nerve biopsy is capable to make a specific diagnosis. We performed a biopsy in the dorsal sensory branch of the ulnar nerve in the hand in 17 patients with ulnar palsy with thickening of the nerve in the elbow, without skin changes. The pathological findings consisted mainly of: loss of fibers (14 cases), inflammatory infiltration (13), fibrosis (12), demyelination and remyelination (9), presence of granuloma (6) and presence of bacilli (5 cases). We conclude that in case of ulnar nerve palsy in leprosy without skin changes, the biopsy of the dorsal sensory branch of this nerve in the hand is a good procedure for the diagnosis of leprosy.
authors.affiliation: Serviço de Neurologia, Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Brasil.
authors.forename: M R
authors.initials: MR
authors.lastname: de Freitas
authors.forename: O J
authors.initials: OJ
authors.lastname: Nascimento
authors.forename: M J
authors.initials: MJ
authors.lastname: Drago
authors.forename: A R
authors.initials: AR
authors.lastname: de Freitas
authors.forename: M D
authors.initials: MD
authors.lastname: Hahn
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D005260:Female; D006225:Hand / Q000294:innervation*; D006801:Humans; D015441:Leprosy, Tuberculoid / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010243:Paralysis / Q000209:etiology* / Q000473:pathology*; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology*; D014459:Ulnar Nerve / Q000473:pathology*
vernacular_title: Paralisia do nervo ulnar na lepra sem alterações cutâneas. Biópsia do ramo superficial do nervo ulnar na mão.