Prenatal and postnatal blood lead level and head circumference in children to three years: preliminary results from the Mexico City Prospective Lead Study.
Multiple regression modeling was used to explore the relationship between prenatal and postnatal blood lead levels and child head circumference in the first three years of life. Maternal blood lead at 36 weeks of pregnancy and cord blood lead were found to be inversely related to 6 month and 18 month head circumference, respectively. Child 12 month blood lead was inversely related to 36 month head circumference. Limitations of the data set and the statistical techniques were discussed, as were the interpretations of the findings.
Rothenberg
S J
SJ
Department of Developmental Neurobiology, National Institute of Perinatology, México, D.F., México.
Schnaas-Arrieta
L
L
Pérez-Guerrero
I A
IA
Perroni-Hernandez
E
E
Mercado-Torres
L
L
Gomez-Ruiz
C
C
Zea
F
F
D000293:Adolescent; D000328:Adult; D002508:Cephalometry; D002675:Child, Preschool; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006130:Growth Disorders / Q000097:blood / Q000139:chemically induced / Q000473:pathology; D006257:Head / Q000254:growth & development / Q000473:pathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007855:Lead Poisoning / Q000097:blood* / Q000150:complications; D008297:Male; D018811:Maternal Exposure / Q000009:adverse effects*; D008800:Mexico; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D011446:Prospective Studies; D012044:Regression Analysis; D014504:Urban Health