title: Reversible ischemia determined by xenon-enhanced CT after 90 minutes of complete basilar artery occlusion.
abstract: Intraarterial thrombolytic therapy decreases mortality in the treatment of acute basilar artery occlusion. An acute decrease in cerebral blood flow (CBF) (<12 mL/100 g per minute) has been reported to invariably result in infarction. We report a case of acute basilar artery occlusion, recanalized within 90 minutes, with reversal of CBF of less than 6 mL/100 g per minute. After reperfusion, areas with persistent CBF of 6 mL/100 g per minute resulted in infarctions on subsequent CT studies. Parenchymal viability is possible after 90 minutes of posterior CBF of 6 mL/100 g per minute.
authors.affiliation: Department of Neurological Surgery, Presbyterian University Hospital, The University of Pittsburgh Medical Center, PA 15213, USA.
authors.forename: E I
authors.initials: EI
authors.lastname: Levy
authors.forename: A M
authors.initials: AM
authors.lastname: Scarrow
authors.forename: E
authors.initials: E
authors.lastname: Kanal
authors.forename: G
authors.initials: G
authors.lastname: Rubin
authors.forename: H
authors.initials: H
authors.lastname: Yonas
authors.forename: L
authors.initials: L
authors.lastname: Kirby
mesh_terms: D000208:Acute Disease; D001921:Brain / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002560:Cerebrovascular Circulation; D003287:Contrast Media; D006801:Humans; D008297:Male; D008875:Middle Aged; D015912:Thrombolytic Therapy; D014057:Tomography, X-Ray Computed; D014715:Vertebrobasilar Insufficiency / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000503:physiopathology; D014978:Xenon
chemical_list: D003287:Contrast Media; D014978:Xenon