title: Development and histologic characteristics of synovitis induced by trauma in the rat temporomandibular joint.
abstract: Histopathological changes caused by trauma to the rat temporomandibular joint synovium were examined by light microscopy. The trauma was induced by forced hypermobility of the condyle. Pathological changes of the synovium were found primarily in the anterior pouch of the upper joint compartment. The main findings included surface cell proliferation, increased capillary hyperemia, fibrin deposits on the surfaces of inflamed synovial membranes, and fibrinous adhesion between closely opposed synovial membranes. A gradual change from fibrinous adhesion to fibrous adhesion was also seen.
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Dentistry, Health Sciences University of Hokkaido, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Muto
authors.forename: J
authors.initials: J
authors.lastname: Kawakami
authors.forename: M
authors.initials: M
authors.lastname: Kanazawa
authors.forename: T
authors.initials: T
authors.lastname: Kaku
authors.forename: T
authors.initials: T
authors.lastname: Yajima
mesh_terms: D000818:Animals; D002200:Capillary Resistance; D002455:Cell Division; D005355:Fibrosis / Q000209:etiology / Q000473:pathology; D007593:Joint Instability / Q000150:complications; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013583:Synovial Membrane / Q000098:blood supply / Q000473:pathology; D013585:Synovitis / Q000209:etiology* / Q000473:pathology*; D013704:Temporomandibular Joint / Q000293:injuries* / Q000473:pathology; D000267:Tissue Adhesions / Q000209:etiology; D014664:Vasodilation