title: Syntheses of 2-[(3,5-dimethyl-4-methoxypyridyl)alkyl]-benzothiazolidine derivatives as a potential gastric H+/K(+)-ATPase inhibitor.
abstract: A series of 2-[(3,5-dimethyl-4-methoxypyridyl)alkyl]benzothiazolidine derivatives were synthesized and tested their inhibitory effects on gastric H+/K(+)-ATPase. Compound 4d exhibited potent in vitro inhibitory activity.
authors.affiliation: Department of Applied Chemistry, Ajou University, Suwon, Korea.
authors.forename: S H
authors.initials: SH
authors.lastname: Yoon
authors.forename: S
authors.initials: S
authors.lastname: Seo
authors.forename: Y
authors.initials: Y
authors.lastname: Lee
authors.forename: S
authors.initials: S
authors.lastname: Hwang
authors.forename: D Y
authors.initials: DY
authors.lastname: Kim
mesh_terms: D000818:Animals; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*; D066298:In Vitro Techniques; D054328:Proton Pump Inhibitors; D051381:Rats; D013270:Stomach / Q000201:enzymology*; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology*
chemical_list: D004791:Enzyme Inhibitors; D054328:Proton Pump Inhibitors; D013844:Thiazoles