[Prostacyclin inhalation in pulmonary failure following smoke inhalation].
A 42 year-old man was admitted to hospital due to smoke inhalation. Thirty-three hours after admission arterial oxygen saturation was 80-90% with FiO2 = 1.0. Inhalation with prostacyclin was commenced with a dose rate of 7 ng/kg/min with an immediate effect, i.e. SATaO2 increased to 100%. Prostacyclin was terminated after 24 hours, when FiO2 was reduced to 0.5. It is concluded that prostacyclin inhalation therapy may have effect in patients following pulmonary smoke injury.
Nielsen
H R
HR
Intensivafdeling 4131, H:S Rigshospitalet, København. Rotboell@dadlnet.dk
Jensen
B F
BF
Heslet
L
L
D000280:Administration, Inhalation; D000328:Adult; D011464:Epoprostenol / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D012131:Respiratory Insufficiency / Q000188:drug therapy* / Q000209:etiology; D015208:Smoke Inhalation Injury / Q000150:complications*
D010975:Platelet Aggregation Inhibitors; D011464:Epoprostenol
Prostacyklininhalation ved lungesvigt efter røgforgiftning.