Epizootics of bovine ephemeral fever on dairy farms in Saudi Arabia.
In 1990 and 1996, field veterinarians suspected the clinical occurrence of bovine ephemeral fever among dairy and conventional cattle in different regions of Saudi Arabia. The disease has a seasonal occurrence; it begins in early summer (May) and ends in late autumn (November). The mortality rate is low: 0.3% to 0.6%. The morbidity rate ranged from 5% to 61% within the different age groups of one affected herd in the 1996 outbreaks and from 3.4% to 19% among four affected herds in the 1990 outbreaks. A sudden sharp drop in milk production occurred in lactating animals, some of which had become dry by the end of the outbreaks. Trials to isolate the causative virus in cell culture and in baby mice were unsuccessful. Serum neutralisation tests, which used a cell culture-adapted vaccine strain of bovine ephemeral fever virus as an antigen, revealed the presence of specific antibodies with significantly increased titres in the convalescent sera of affected animals. In addition, the testing of paired sera from non-affected heifers and from both dry and milking cows, performed twice, with an interval of 21 days, revealed the presence of neutralising antibodies. In the 1990 outbreaks, comparative serological studies indicated a high percentage (67.5%; 27/40) of seropositive animals in herds in which bovine ephemeral fever had been previously suspected. No antibodies were detected in animals of herds which had no recorded clinical history of bovine ephemeral fever. Following serological confirmation of the prevalence of bovine ephemeral fever in Saudi Arabia, some dairy farms started using a live imported vaccine to control the disease. This study discusses the epizootiological findings in regard to bovine ephemeral fever, as well as its economic impact on four affected dairy farms in 1990. In addition, the authors evaluate the efficacy of immunoprophylaxis in another dairy herd during the same outbreaks.
Farag
M A
MA
National Agriculture and Water Research Center, Riyadh, Saudi Arabia.
al-Sukayran
A
A
Mazloum
K S
KS
al-Bukomy
A M
AM
D000208:Acute Disease; D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002417:Cattle; D002519:Ceratopogonidae / Q000821:virology; D002522:Chlorocebus aethiops; D003289:Convalescence; D009033:Culicidae / Q000821:virology; D003612:Dairying / Q000191:economics / Q000706:statistics & numerical data; D004196:Disease Outbreaks / Q000662:veterinary*; D004810:Ephemeral Fever / Q000191:economics / Q000453:epidemiology*; D018115:Ephemeral Fever Virus, Bovine / Q000276:immunology / Q000302:isolation & purification; D005260:Female; D007303:Insect Vectors / Q000821:virology; D008297:Male; D051379:Mice; D009017:Morbidity; D009500:Neutralization Tests / Q000662:veterinary; D012529:Saudi Arabia / Q000453:epidemiology; D012621:Seasons; D014611:Vaccination / Q000662:veterinary; D014709:Vero Cells; D014765:Viral Vaccines / Q000276:immunology
D000914:Antibodies, Viral; D014765:Viral Vaccines