[Ion-sensitive endogenous regulators of Na+,K+-ATPase obtained from epithelium of rat small intestine].
From epithelial layer of rat intestinal were selected water soluble substances which influenced on Na+,K(+)-ATPase activity in 2 different ways: substances with molecular weight 220 Da, 400 Da were its activators, substance with weight 150 Da-inhibitor. Na+,K(+)-ATPase activators preincubated previously with Na+ acquire properties of inhibitors. Bivalent cations Ca, Mg remove this effect of Na-ions.
Iaremenko
M S
MS
O.O. Bogomolets Institute Physiology of NAS Ukraine, Kyiv.
Kharlamova
O M
OM
D000818:Animals; D002118:Calcium / Q000378:metabolism; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000378:metabolism; D007413:Intestinal Mucosa / Q000201:enzymology*; D007421:Intestine, Small / Q000201:enzymology*; D008274:Magnesium / Q000378:metabolism; D008970:Molecular Weight; D051381:Rats; D017208:Rats, Wistar; D012964:Sodium / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000502:physiology*; D012995:Solubility
D004791:Enzyme Inhibitors; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D008274:Magnesium; D002118:Calcium
Ionchutlyvi endohenni rehuliatory Na+,K+-ATP-azi, oderzhani z epiteliiu tonkoï kyshky shchura.