title: [State of antioxidant and oxygen transport system of the blood in the process of adaptation of the body to hypoxic hypoxia].
abstract: This article shows that in oxygen transported and antioxidative systems considerable changes take place during dynamic of adaptation to oxygen deficiency of inhaled air (every day 4 hours stay of animals in barochamber under pO2 7.45 kPa during 12 days). Single influence of hypoxic factor induced in erythrocytes peripheral blood increasing of haemoglobin affinity to oxygen, decreasing SOD and catalase activity on the background of increasing of malon aldehyde level. On 12-th day of adaptation of animals contents of TBA-active products in erythrocytes is saved on high level, activity of antioxidative enzymes is approached to original meanings, haemoglobin affinity to oxygen is decreased in comparison with control. Detected increasing content of creatine in erythrocytes during dynamic of rat adaptation to hypoxic hypoxia witnessed about erythropoiesis activation and quickened exit out of marrow young forms of erythrocytes.
authors.affiliation: Franko State Universyti, Lviv.
authors.forename: N V
authors.initials: NV
authors.lastname: Pavliuk
authors.forename: O M
authors.initials: OM
authors.lastname: Krys'ko
authors.forename: N I
authors.initials: NI
authors.lastname: Klymyshyn
authors.forename: Ie M
authors.initials: IeM
authors.lastname: Golubiĭ
authors.forename: V M
authors.initials: VM
authors.lastname: Korobov
authors.forename: K P
authors.initials: KP
authors.lastname: Dudok
authors.forename: M M
authors.initials: MM
authors.lastname: Velykyĭ
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D001692:Biological Transport / Q000502:physiology; D002374:Catalase / Q000097:blood; D004912:Erythrocytes / Q000378:metabolism; D000860:Hypoxia / Q000097:blood*; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D010100:Oxygen / Q000097:blood / Q000493:pharmacokinetics*; D051381:Rats; D013482:Superoxide Dismutase / Q000097:blood
chemical_list: D000975:Antioxidants; D008315:Malondialdehyde; D002374:Catalase; D013482:Superoxide Dismutase; D010100:Oxygen
vernacular_title: Stan antyoksydantnoï ta kysnevo-transportnoï system krovi v protsesi adaptatsiï orhanizmu do hipoksychnoï gipoksiï.