Rash, fever, and chills after intravenous fluorescein angiography.
OBJECTIVE
To report a previously unreported complication associated with intravenous injection of fluorescein dye.


METHODS
Case report. A 75-year-old man developed a unique complication after intravenous injection of fluorescein dye for angiography.


RESULTS
Two hours after receiving an intravenous injection of fluorescein for angiography, the patient developed a fever, rash, and chills. Admission to a hospital and careful systemic evaluation determined that this reaction was a noninfectious allergic response to intravenous fluorescein dye injection.


CONCLUSIONS
A delayed allergic response to intravenous fluorescein dye injection can occur.
Johnson
R N
RN
retinasf@aol.com
McDonald
H R
HR
Schatz
H
H
D000368:Aged; D004342:Drug Hypersensitivity / Q000209:etiology*; D005076:Exanthema / Q000139:chemically induced*; D005334:Fever / Q000139:chemically induced*; D019793:Fluorescein / Q000008:administration & dosage / Q000009:adverse effects*; D005451:Fluorescein Angiography / Q000009:adverse effects*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D009883:Ophthalmic Solutions; D012768:Shivering
D009883:Ophthalmic Solutions; D019793:Fluorescein