title: Gastro-oesophageal reflux in children.
abstract: Disordered motility of the gastrointestinal tract in children is usually manifest as gastro-oesophageal reflux disease. Reflux is common in infants but usually resolves spontaneously with time. If severe enough to merit investigation, 24-hour ambulant oesophageal pH monitoring is the most widely used investigation, though it does have disadvantages. Upper gastrointestinal endoscopy and biopsy may be required to diagnose oesophagitis. Treatment follows a step-wise approach, progressing from positioning and feed-thickening in infants, through to pharmacological management with prokinetic agents and/or acid-suppression, and surgery for a very small proportion of children whose symptoms do not respond to optimal medical therapy.
authors.affiliation: Department of Child Health, Singleton Hospital, Sketty, Swansea, UK.
authors.forename: M
authors.initials: M
authors.lastname: Cosgrove
authors.forename: J
authors.initials: J
authors.lastname: Dodge
mesh_terms: D002648:Child; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D006801:Humans