title: [Indications for carotid endarterectomy in patients with symptoms: when, where?].
abstract: Carotid endarterectomy (CEA) is one of the most commonly used surgical methods in the treatment of cerebral stroke with both therapeutic and also prophylactic implications. CEA has been used in surgical practice for 40 years. At the beginning it was very popular and was widely used. Later, the opposite extreme was reached, and its therapeutic efficacy was denied unjustifiably. However, at the beginning of the ninetieth three large controlled studies were completed (North American Symptomatic Carotid Endarterectomy Trial, European Carotid Surgery Trial and Veterans Administrations Symptomatic Trial) and the results of these trials were the basis for establishing the solid criteria for the surgical procedure in some groups of symptomatic patients with stenosis of the internal carotid artery. Thus, CEA was in again. In accordance with the attitudes of the American Association Ad Hoc Committee (1995), evidenced indications for CEA in patients with symptomatic stenosis of the internal carotid artery (in the group with surgical risk less than 6%) include (a) single or recurrent episodes of TIA in the last 6 months, "crescendo" TIA combined with carotid stenosis > 70% with or without plaque ulceration, with or without antiplatelet therapy, and (b) mild stroke in last 6 months with carotid stenosis > 70% with or without plaque ulceration, with or without antiplatelet therapy. The authors report their experience and results of a six-month pilot study of 301 patients, of whom 248 were operated on for symptomatic carotid stenosis with low combined perioperative morbidity and mortality (0.6%). Also, indications for surgical reconstruction of carotid and coronary arteries in patients with marked signs of atherosclerosis in both arterial systems are discussed.
authors.affiliation: Institute of Neurology, Clinical Centre of Sebia, Belgrade.
authors.forename: N M
authors.initials: NM
authors.lastname: Coviković-Sternić
authors.forename: Dj J
authors.initials: DjJ
authors.lastname: Radak
authors.forename: V S
authors.initials: VS
authors.lastname: Kostić
mesh_terms: D016893:Carotid Stenosis / Q000601:surgery; D016894:Endarterectomy, Carotid / Q000706:statistics & numerical data*; D006801:Humans; D002546:Ischemic Attack, Transient / Q000601:surgery
vernacular_title: Indikacije za karotidnu endarterektomiju kod bolesnika sa simptomima: kome, kada?