title: Atopic dermatitis apparently caused by type 2 CD8+ T cells in an AIDS patient.
abstract: A patient with atopic dermatitis and acquired immune deficiency syndrome (AIDS) had demonstrated blood eosinophilia, high levels of serum IgE and intracytoplasmic IL-4 in the CD8+ but not in the CD4+ cells, decreased numbers of CD4+ cells, and low levels of IL-2 in both CD4+ and CD8+ cells. These results, reflecting a predominant influence of type 2 CD8+ cells, suggest they were involved in the genesis exacerbation of the patient's atopic dermatitis.
authors.affiliation: Department of Dermatology, Yokohama City University School of Medicine, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Ishii
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: Y
authors.initials: Y
authors.lastname: Sugita
authors.forename: H
authors.initials: H
authors.lastname: Nakajima
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D003876:Dermatitis, Atopic / Q000276:immunology*; D006801:Humans; D007376:Interleukin-2 / Q000096:biosynthesis; D015847:Interleukin-4 / Q000096:biosynthesis; D008297:Male; D008875:Middle Aged
chemical_list: D007376:Interleukin-2; D015847:Interleukin-4