Does overexpression of betaAPP in aging muscle have a pathogenic role and a relevance to Alzheimer's disease? Clues from inclusion body myositis, cultured human muscle, and transgenic mice.
Askanas
V
V
Neuromuscular Center, Department of Neurology, University of Southern California School of Medicine, Good Samaritan Hospital, Los Angeles 90017-1912, USA. askanas@hsc.usc.edu
Engel
W K
WK
D000367:Age Factors; D000544:Alzheimer Disease / Q000503:physiopathology*; D016564:Amyloid beta-Protein Precursor / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D002478:Cells, Cultured; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D009132:Muscles / Q000166:cytology / Q000378:metabolism* / Q000473:pathology; D018979:Myositis, Inclusion Body / Q000378:metabolism* / Q000473:pathology; D012333:RNA, Messenger / Q000378:metabolism; D014162:Transfection
D016564:Amyloid beta-Protein Precursor; D012333:RNA, Messenger