[Image analysis of tumor cells from common intracranial neoplasms on frozen and paraffined slices].
Image analysis technique was used to measure four parameters [the form factor (FF), area, perimeter and diameter] of nuclei in 76 cases of common intracranial tumors on forzen and paraffined slices. The results showed that the area, perimeter, diameter of nuclei on frozen slices were much larger than those on paraffined slices while the FF showed no significant difference between two kinds of slices (P > 0.05). The parameters of the area, perimeter, and diameter of nuclei on two kinds of slices became larger and the parameters of FF became smaller as the grade of astrocytoma ascended. It is considered that the results of present study will be helpful to the diagnosis of common intracranial tumors on frozen slices.
Zhou
J
J
Department of Pathology, Hunan Medical University, Changsha.
Sheng
M
M
Chen
C
C
Yang
X
X
D001254:Astrocytoma / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology*; D002467:Cell Nucleus / Q000648:ultrastructure; D005629:Frozen Sections; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016612:Paraffin Embedding