title: Ophthalmoplegic migraine: reversible enhancement and thickening of the cisternal segment of the oculomotor nerve on contrast-enhanced MR images.
abstract: OBJECTIVE
  Ophthalmoplegic migraine is a rare condition characterized by the association of headaches and an oculomotor nerve palsy. We report six patients with typical clinical features of this disorder in whom enhancement of the cisternal segment of the oculomotor nerve developed during the acute phase, followed by resolution of enhancement over several weeks as the symptoms resolved.
  
  
  METHODS
  Six patients, ages 3 to 27 years, underwent MR imaging during the acute phase of ophthalmoplegic migraine and at the time of recovery several weeks later. The MR studies, performed on a 1.5-T MR unit, included noncontrast and contrast-enhanced axial and coronal T1-weighted sequences. Sagittal images were obtained in two patients, with and without contrast enhancement.
  
  
  RESULTS
  Enhancement of the cisternal segment of the oculomotor nerve was seen in all patients at initial presentation. Contrast-enhanced studies also showed focal thickening at the exit of the nerve in the interpeduncular cistern in five of six patients. No patient had enhancement of the cavernous sinus or adjacent dura. Enhancement was almost completely resolved on follow-up studies 7 to 9 weeks later.
  
  
  CONCLUSIONS
  Our findings confirm an intrinsic transient abnormality in the cisternal segment of the third nerve in patients with a typical clinical presentation of ophthalmoplegic migraine.
authors.affiliation: Washington Hospital Center, Washington, DC 20010, USA.
authors.forename: A S
authors.initials: AS
authors.lastname: Mark
authors.forename: J
authors.initials: J
authors.lastname: Casselman
authors.forename: D
authors.initials: D
authors.lastname: Brown
authors.forename: J
authors.initials: J
authors.lastname: Sanchez
authors.forename: M
authors.initials: M
authors.lastname: Kolsky
authors.forename: T C
authors.initials: TC
authors.lastname: Larsen
authors.forename: P
authors.initials: P
authors.lastname: Lavin
authors.forename: B
authors.initials: B
authors.lastname: Ferraraccio
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008881:Migraine Disorders / Q000150:complications* / Q000473:pathology; D009802:Oculomotor Nerve / Q000473:pathology*; D015840:Oculomotor Nerve Diseases / Q000150:complications* / Q000473:pathology
chemical_list: D003287:Contrast Media