[DNA synthesis in lymphocytes of irradiated animals as affected by mitogens and Staphylococcal antigens].
Proliferation activity of lymphocytes from rats was studied using micromethod of blast transformation reaction after exposure of X-ray irradiation (absorbed doses for animals are 0.5 and 1 Gr). The reducing of the functional activity of lymphocytes was found. There was difference in lymphocyte response induced by standard mitogens (PHA, ConA, LPS) and antigens of Staphylococcus protein A and peptidoglycan. The irradiation protective effects of Staphylococcus substances were found.
Kholodna
L S
LS
T.Shevchenko University, Kyiv, Ukraine.
Pozur
V K
VK
Liubchenko
T A
TA
Hritsenko
L M
LM
Holeva
O H
OH
Kucherenko
M Ie
MIe
D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology*; D002455:Cell Division / Q000187:drug effects / Q000276:immunology / Q000528:radiation effects; D003208:Concanavalin A / Q000494:pharmacology; D004247:DNA / Q000096:biosynthesis*; D008070:Lipopolysaccharides / Q000494:pharmacology; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology / Q000528:radiation effects*; D008934:Mitogens / Q000494:pharmacology*; D010835:Phytohemagglutinins / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D013205:Staphylococcal Protein A / Q000276:immunology*; D013211:Staphylococcus aureus / Q000276:immunology*
D000942:Antigens, Bacterial; D008070:Lipopolysaccharides; D008934:Mitogens; D010835:Phytohemagglutinins; D013205:Staphylococcal Protein A; D003208:Concanavalin A; D004247:DNA
Syntez DNK u limfotsytakh oprominenykh tvaryn pid vplyvom mitoheniv i antyheniv stafilokoka.