title: Electroencephalographic discharges of temporal lobe seizures in children and young adults.
abstract: We investigated the discharge morphology and propagation patterns of electroencephalographic seizures of temporal lobe onset in 21 children and young adults who underwent invasive long-term EEG monitoring (LTM). Of those, 15 subsequently underwent anterior temporal lobectomy. The onset was focal in 63%. The most frequent discharge morphology was low amplitude beta (30%) or rhythmic/semirhythmic theta discharge (30%). Thirteen patients displayed several sequences of propagation with different spreading stages along a fixed path. Initial spreading to the ipsilateral frontal lobe was associated with a higher frequency of secondary generalization than initial spreading to the contralateral temporal lobe (P = 0.18). A comparison of 13 patients older than 18 years of age with 8 patients younger than 14 years showed a trend towards a lower rate of propagating from the temporal lobe (P = 0.13) in the younger age group. Discharge morphology was not correlated with age, focality, or outcome of surgery.
authors.affiliation: Department of Pediatric Neurology, Tel-Aviv Sourasky Medical Center and The Sackler Faculty of Medicine, Tel-Aviv University, Israel.
authors.forename: U
authors.initials: U
authors.lastname: Kramer
authors.forename: L
authors.initials: L
authors.lastname: Carmant
authors.forename: M A
authors.initials: MA
authors.lastname: Mikati
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology*; D002648:Child; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000503:physiopathology* / Q000601:surgery; D005500:Follow-Up Studies; D005794:Generalization, Response / Q000502:physiology; D006801:Humans; D013702:Temporal Lobe / Q000503:physiopathology; D013826:Theta Rhythm