title: Adenocarcinoma in situ of the fallopian tube. A case report.
abstract: BACKGROUND
  So far only a few cases of carcinoma in situ of the fallopian tube have been reported, but its detailed clinical and pathologic findings, including cytology, have not been fully described.
  
  
  METHODS
  A 70-year-old female was admitted to our hospital because of irregular genital bleeding. Endometrial smear revealed a small number of atypical cells with a clear background. Hysterectomy, bilateral salpingo-oophorectomy and omentectomy were performed. Grossly, a grayish white papillary tumor, measuring 1.5 x 1.0 cm, was observed within the lumen of the left fallopian tube. Microscopically, the diagnosis of papillary adenocarcinoma in situ of the left fallopian tube was made according to 1992 International Federation of Gynecologists and Obstetricians fallopian tube staging.
  
  
  CONCLUSIONS
  Although endometrial brush cytology is not sensitive enough to detect a primary carcinoma of the fallopian tube, our case indicates that it may contribute useful information on extrauterine diseases and can detect a stage 0 cancer of the fallopian tube. Clinicians, as well as pathologists, should consider the possibility of fallopian tube cancer if cervical or endometrial cytology shows atypical cells with papillary patterns with a clear background but endometrial curettage cannot prove malignancy.
authors.affiliation: Department of Pathology, Ishikawa Prefectural Central Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Minato
authors.forename: M
authors.initials: M
authors.lastname: Shimizu
authors.forename: M
authors.initials: M
authors.lastname: Hirokawa
authors.forename: K
authors.initials: K
authors.lastname: Fujiwara
authors.forename: I
authors.initials: I
authors.lastname: Kohno
authors.forename: T
authors.initials: T
authors.lastname: Manabe
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D002278:Carcinoma in Situ / Q000473:pathology*; D002291:Carcinoma, Papillary / Q000473:pathology; D004717:Endometrium / Q000473:pathology*; D005185:Fallopian Tube Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D010535:Laparoscopy