title: Aryl phosphate derivatives of 3'-deoxythymidine are not potent anti-human immunodeficiency virus agents.
abstract: Aryl phosphate derivatives of 3'-deoxythymidine (3dT), albeit more active than 3dT in thymidine kinase (TK)-deficient cells, are not potent anti-human immunodeficiency virus (HIV) agents and are capable of inhibiting HIV replication only at micromolar concentrations.
authors.affiliation: Drug Discovery Program, Hughes Institute, St Paul, Minnesota 55113, USA.
authors.forename: R
authors.initials: R
authors.lastname: Vig
authors.forename: T K
authors.initials: TK
authors.lastname: Venkatachalam
authors.forename: S T
authors.initials: ST
authors.lastname: Jan
authors.forename: F M
authors.initials: FM
authors.lastname: Uckun
mesh_terms: D019380:Anti-HIV Agents / Q000737:chemistry* / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010710:Phosphates / Q000737:chemistry* / Q000494:pharmacology; D013936:Thymidine / Q000031:analogs & derivatives*; D014779:Virus Replication / Q000187:drug effects
chemical_list: D019380:Anti-HIV Agents; D000998:Antiviral Agents; D010710:Phosphates; D013936:Thymidine