A new prenylated flavonol from the roots of Sophora flavescens.
A new prenylated flavonol, sophoflavescenol (1), together with five known flavonoids, kurarinol, kushenol K, kushenol H, trifolirhizin, and kuraidin, were isolated from the roots of Sophora flavescens. The structure of 1 was determined by spectroscopic analysis. Among the five known flavonoids, kurarinol, kushenol K, and kushenol H showed weak antiviral activity against Herpes simplex virus types I and II.
Woo
E R
ER
Division of Applied Science, Korea Institute of Science & Technology, P.O. Box No. 131, Cheongryang, Seoul 130-650, Korea.wooer@kistmail.kis t.re.kr
Kwak
J H
JH
Kim
H J
HJ
Park
H
H
D000998:Antiviral Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002681:China; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology*; D018259:Herpesvirus 1, Human / Q000187:drug effects*; D018258:Herpesvirus 2, Human / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D018517:Plant Roots / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
D000998:Antiviral Agents; D005419:Flavonoids; C117237:sophoflavescenol