title: Cough-induced leak-point pressure--a valid measure for assessing treatment in women with stress incontinence.
abstract: BACKGROUND
  Presently available urodynamic methods are of little use for assessing the severity of urinary stress incontinence or for evaluating of treatment, Cough-induced leak-point pressure may prove to be a more useful urodynamic method in these respects. A vaginal anti-incontinence device was used to validate this new urodynamic method.
  
  
  OBJECTIVE
  The primary aim was to determine the extent to which cough-induced leak-point pressure was affected by the vaginal device. Secondary aims were to study the short-term effects of the vaginal device on leakage and urinary flow, and to relate the change in cough-induced leak-point pressure to the change in leakage as expressed by a short-term pad test.
  
  
  METHODS
  In a prospective study of 22 women with a history of stress incontinence, the effect of a new vaginal anti-incontinence device (Conveen Continence Guard) on cough-induced leak-point pressure, a short-term pad test and urinary flow was studied.
  
  
  RESULTS
  Cough-induced leak-point pressure increased from 99.9 to 138.9 cm H2O, while leakage, measured by a short-term pad test, decreased from 22.7 to 3.3 g when using the device. Urinary flow was not significantly reduced by the device.
  
  
  CONCLUSIONS
  Cough-induced leak-point pressure is a valid, quantitative, dynamic measure of urethral closure function which can be used to study the effects of treatment in patients with stress incontinence. The vaginal device is effective for treatment of stress incontinence in the short-term, without reducing urinary flow.
authors.affiliation: Department of Obstetrics and Gynecology, Akademiska Hospital and Uppsala University, Sweden.
authors.forename: H
authors.initials: H
authors.lastname: Siltberg
authors.forename: G
authors.initials: G
authors.lastname: Larsson
authors.forename: A
authors.initials: A
authors.lastname: Victor
mesh_terms: D000328:Adult; D000368:Aged; D003371:Cough; D004867:Equipment Design; D005260:Female; D006801:Humans; D008875:Middle Aged; D011312:Pressure; D011446:Prospective Studies; D013812:Therapeutics / Q000295:instrumentation; D014550:Urinary Incontinence, Stress / Q000503:physiopathology / Q000628:therapy*; D014563:Urodynamics