title: Fat-plug and paper-patch myringoplasty in rats.
abstract: OBJECTIVE
  The purpose of this study is to investigate the recovery rate in paper-patch and fat-plug myringoplasty in rats.
  
  
  METHODS
  Small and large perforations were inflicted on the tympanic membranes of 60 rats. Fat-plug and paper-patch myringoplasties were performed to different groups and another group was left for spontaneous healing.
  
  
  RESULTS
  We found that for small perforations, the recovery rate was 94.7% in fat-plug myringoplasty, 94.4% in paper-patch myringoplasty, and 66.6% in control group. The recovery rates in large perforations were 52.9%, 56.2%, and 26.6%, respectively. On the other hand, in larger perforations, paper-patch or fat-plug myringoplasty have not been found effective.
  
  
  CONCLUSIONS
  We believe that due to significant operational advantages, fat-plug or paper-patch myringoplasty can be suggested for the reconstruction of small and dry perforations of the tympanic membrane.
authors.affiliation: Department of Otorhinolaryngology, School of Medicine, Karadeniz Teknik University, Trabzon, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Imamoğlu
authors.forename: A U
authors.initials: AU
authors.lastname: Işik
authors.forename: O
authors.initials: O
authors.lastname: Acuner
authors.forename: G
authors.initials: G
authors.lastname: Harova
authors.forename: O
authors.initials: O
authors.lastname: Bahadir
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D000818:Animals; D001284:Atrophy; D004195:Disease Models, Animal; D004432:Ear, Middle / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D009225:Myringoplasty / Q000379:methods*; D010209:Paper; D051381:Rats; D017208:Rats, Wistar; D013701:Temporal Bone / Q000473:pathology; D014432:Tympanic Membrane / Q000473:pathology; D018058:Tympanic Membrane Perforation / Q000145:classification / Q000473:pathology / Q000601:surgery; D014945:Wound Healing