title: Cardiac malignant pheochromocytoma with bone metastases.
abstract: A patient with malignant cardiac pheochromocytoma with bone metastases is described. The primary tumor was located between the pulmonary trunk and the left atrium, while metastatic lesions were found in the iliac bones. Treatments with antihypertensive agents, alpha-methylparatyrosine, and combination chemotherapy with cyclophosphamide, vincristine, and dacarbazine partially improved the patient's symptoms, catecholamine levels, and the metastatic lesion of the iliac bones. However, the primary tumor in the heart progressively increased in size and the patient died of disseminated intravascular coagulation and other various complications about 4 years after the diagnosis of the disease.
authors.affiliation: Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women's Medical University.
authors.forename: A
authors.initials: A
authors.lastname: Arai
authors.forename: M
authors.initials: M
authors.lastname: Naruse
authors.forename: K
authors.initials: K
authors.lastname: Naruse
authors.forename: A
authors.initials: A
authors.lastname: Tanabe
authors.forename: T
authors.initials: T
authors.lastname: Yoshimoto
authors.forename: T
authors.initials: T
authors.lastname: Iwama
authors.forename: K
authors.initials: K
authors.lastname: Kusakabe
authors.forename: T
authors.initials: T
authors.lastname: Obara
authors.forename: R
authors.initials: R
authors.lastname: Demura
authors.forename: H
authors.initials: H
authors.lastname: Demura
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D001859:Bone Neoplasms / Q000097:blood / Q000188:drug therapy / Q000556:secondary*; D002395:Catecholamines / Q000097:blood; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006338:Heart Neoplasms / Q000097:blood / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007085:Ilium; D008875:Middle Aged; D010673:Pheochromocytoma / Q000097:blood / Q000188:drug therapy / Q000556:secondary*
chemical_list: D014408:Biomarkers, Tumor; D002395:Catecholamines