title: [Spasmophilia in children and the anticonvulsant properties of a new Ukrainian preparation containing a pyrimidine derivative].
abstract: Tablets valcophen, which are containing the pyrimidine's derivative, have an acute anticonvulsive activity. Tablets valcophen and granules phenobarbital for children are having the same activity, which have been marked about lower intensity convulsions, quantity of a lived animals and also lengthening a time of deathing mice. These investigations are showing that tablets valcophen may be used for treatment convulsive state in children.
authors.affiliation: Ukrainian Pharmaceutical Academy, Ministry of Public Heath of Ukraine, Kharkov.
authors.forename: V O
authors.initials: VO
authors.lastname: Shapovalova
authors.forename: V V
authors.initials: VV
authors.lastname: Shapovalov
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000627:therapeutic use*; D001241:Aspirin / Q000627:therapeutic use*; D002110:Caffeine / Q000627:therapeutic use*; D002648:Child; D003292:Convulsants; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D006801:Humans; D051379:Mice; D010433:Pentylenetetrazole; D010634:Phenobarbital / Q000627:therapeutic use*; D013607:Tablets; D013746:Tetany / Q000139:chemically induced / Q000188:drug therapy*
chemical_list: D000927:Anticonvulsants; D003292:Convulsants; D004338:Drug Combinations; D013607:Tablets; C116569:valcophen; D002110:Caffeine; D001241:Aspirin; D010433:Pentylenetetrazole; D010634:Phenobarbital
vernacular_title: Spazmofiliia u diteĭ ta protysudomni vlastyvosti novoho vitchyznianoho preparatu, shcho vmishchuie pokhidnyĭ pirymidynu.