title: [Treatment of mucosal leishmaniasis with aminosidine sulfate: results of two year follow-up].
abstract: In 1996, 20 of 21 patients with mucosal leishmaniasis, treated in 1994 with aminosidine sulfate, 16mg/kg/day salt, by intramuscular injection for 20 days, were clinically evaluated. One patient died due to disease not related to mucosal leishmaniasis. Seven of 14 patients (66.7% N = 21) who achieved complete remission three months after treatment remained clinically cured 24 months later and seven relapsed in the same period (50% N = 14). Sorological follow-up showed poor correlation with the results of clinical examination.
authors.affiliation: Núcleo de Medicina Tropical e Nutrição/Universidade de Brasília. gromero@guarany.cpd.unb.br
authors.forename: G A
authors.initials: GA
authors.lastname: Romero
authors.forename: H A
authors.initials: HA
authors.lastname: Lessa
authors.forename: M G
authors.initials: MG
authors.lastname: Orge
authors.forename: V O
authors.initials: VO
authors.lastname: Macêdo
authors.forename: P D
authors.initials: PD
authors.lastname: Marsden
mesh_terms: D000563:Amebicides / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D005500:Follow-Up Studies; D006801:Humans; D007273:Injections, Intramuscular; D007892:Leishmania braziliensis; D007897:Leishmaniasis, Mucocutaneous / Q000188:drug therapy*; D010303:Paromomycin / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000563:Amebicides; D010303:Paromomycin
vernacular_title: Tratamento da leishmaniose mucosa com sulfato de aminosidine: resultados de dois anos de acompanhamento.