Inhibitory effect of Garcinia kola on lipid peroxidation in rat liver homogenate.
Garcinia kola, (a herb grown in Nigeria; calorific value 358.54 k.cal/100 g) inhibited in vitro lipid peroxidation of rat liver homogenate in a dose dependent manner. The inhibitory activity of G.kola was not affected by heating (100 degrees C/10 min). The antioxidant component of G.kola was soluble in aqueous and ethanolic media. The active component(s) in G. kola responsible for its inhibitory activity on lipid peroxidation is tentatively identified as isoflavones.
Adegoke
G O
GO
Department of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore, India.
Kumar
M V
MV
Sambaiah
K
K
Lokesh
B R
BR
D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology; D066298:In Vitro Techniques; D007529:Isoflavones / Q000302:isolation & purification / Q000494:pharmacology; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar
D000975:Antioxidants; D007529:Isoflavones; D010936:Plant Extracts