title: Derivatization of soyasapogenol A and their hepatoprotective activities.
abstract: Fifteen derivatives of soyasapogenol A (1), which is another aglycon moiety of soyasaponins from soybean together with soyasapogenol B (2), were prepared and their in vitro hepatoprotective effects were evaluated.
authors.affiliation: Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd., Yokohama, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sasaki
authors.forename: N
authors.initials: N
authors.lastname: Minowa
authors.forename: H
authors.initials: H
authors.lastname: Kuzuhara
authors.forename: S
authors.initials: S
authors.lastname: Nishiyama
authors.forename: S
authors.initials: S
authors.lastname: Omoto
mesh_terms: D002478:Cells, Cultured; D006801:Humans; D008099:Liver / Q000187:drug effects*; D008956:Models, Chemical; D008958:Models, Molecular; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D013025:Glycine max; D013329:Structure-Activity Relationship
chemical_list: D010936:Plant Extracts; C116604:soyasapogenol A; D009828:Oleanolic Acid