title: Prevalence differences in depression among males and females: are there evolutionary explanations?
abstract: Differences in male-female prevalence rates of depression are interpreted in evolutionary perspective. Three evolutionary hypotheses are evaluated: (a) depression represents an evolved strategy to deal with adverse social interactions, particularly among partners, (b) depression has self-preservative and manipulative features, and (c) depression is a consequence of failing to achieve biological goals. While these hypotheses are not necessarily mutually exclusive, evolutionary explanations often suffer from not specifying which hypothesis is primary and which are secondary. We argue that failing to achieve biological goals is primary and that evolved strategies and self-preservative and manipulative behaviour are secondary. Findings pointing to depression-contributing features of male-female differences, asymmetries in male-female relationships and male-female differences associated with reproduction are discussed to support our view that evolutionary explanations can adequately account for a significant percentage of the reported prevalence differences.
authors.affiliation: Neuropsychiatric Institute, School of Medicine, University of California at Los Angeles, 90024, USA.
authors.forename: M T
authors.initials: MT
authors.lastname: McGuire
authors.forename: A
authors.initials: A
authors.lastname: Troisi
mesh_terms: D000223:Adaptation, Psychological; D005075:Biological Evolution; D003866:Depressive Disorder / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D012098:Reproduction; D012737:Sex Factors; D012919:Social Behavior