title: Postoperative management following massive hepatectomy in a patient with Dubin-Johnson syndrome: report of a case.
abstract: We report herein the case of a 46-year-old man with Dubin-Johnson syndrome (DJS) who was referred to our hospital to undergo a right hepatic lobectomy for hepatocellular carcinoma. His complicated postoperative conjugated hyperbilirubinemia was successfully treated by hemopurification based on the increased level of serum hepatocyte growth factor (HGF). It is considered that hemopurification based on the early postoperative HGF levels has beneficial effects for patients with DJS; however, the specific role of hemopurification in the conjugated hyperbilirubinemia that develops postoperatively in these patients has not been determined.
authors.affiliation: First Department of Surgery, Kagoshima University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Ueno
authors.forename: G
authors.initials: G
authors.lastname: Tanabe
authors.forename: K
authors.initials: K
authors.lastname: Hanazono
authors.forename: H
authors.initials: H
authors.lastname: Ogawa
authors.forename: S
authors.initials: S
authors.lastname: Yoshidome
authors.forename: T
authors.initials: T
authors.lastname: Aikou
authors.forename: A
authors.initials: A
authors.lastname: Yoshida
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000473:pathology / Q000601:surgery*; D006498:Hepatectomy; D017228:Hepatocyte Growth Factor / Q000097:blood; D006801:Humans; D006932:Hyperbilirubinemia / Q000097:blood / Q000209:etiology / Q000628:therapy*; D007566:Jaundice, Chronic Idiopathic / Q000150:complications* / Q000175:diagnosis; D008113:Liver Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D010956:Plasmapheresis; D011182:Postoperative Care
chemical_list: D017228:Hepatocyte Growth Factor