title: Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures.
abstract: We evaluated the use of a new, controlled-release capsule form of carbamazepine, Carbatrol capsules, in an open-label, multicenter study of 124 patients with complex partial seizures. Ninety-one percent of the patients successfully completed the 6-month trial with good seizure control, with a significant improvement in quality of life. We conclude that switching patients with complex partial seizures from multiple daily-dose carbamazepine to twice-daily Carbatrol on a milligram-to-milligram basis is relatively safe.
authors.affiliation: Department of Neurology, DePaul Hospital, Bridgeton, MO 63044, USA.
authors.forename: W U
authors.initials: WU
authors.lastname: Mirza
authors.forename: I W
authors.initials: IW
authors.lastname: Rak
authors.forename: V M
authors.initials: VM
authors.lastname: Thadani
authors.forename: J J
authors.initials: JJ
authors.lastname: Cereghino
authors.forename: W R
authors.initials: WR
authors.lastname: Garnett
authors.forename: L M
authors.initials: LM
authors.lastname: Brown
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: G W
authors.initials: GW
authors.lastname: Belendiuk
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000927:Anticonvulsants / Q000008:administration & dosage*; D002220:Carbamazepine / Q000008:administration & dosage*; D003692:Delayed-Action Preparations; D017029:Epilepsy, Complex Partial / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000927:Anticonvulsants; D003692:Delayed-Action Preparations; D002220:Carbamazepine