[Thymoma and pancytopenia].
Thymomas are often associated with a variety of autoimmune disorders including various cytopenias. Rare cases have been associated with pancytopenia. We describe a patient with an invasive thymoma treated with thymectomy and subsequent radiation therapy. A few months later, rapidly progressing pancytopenia developed. Treatment with antibiotics, immunoglobulin, high-dose steroids and granulocyte-colony stimulating factor (G-CSF) had no effect, and the patient died within two months of overwhelming septicaemia complicated with intracranial haemorrhage. We review the literature and discuss therapies.
Danchell
V H
VH
Aalborg Sygehus, medicinsk haematologisk afdeling B.
Mertz
H
H
D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D010198:Pancytopenia / Q000188:drug therapy / Q000209:etiology*; D013945:Thymoma / Q000097:blood / Q000150:complications* / Q000628:therapy
Tymom og pancytopeni.