title: Reproducibility of breath hydrogen concentration measurements in dogs after change of diet.
abstract: OBJECTIVE
  To assess reproducibility of breath hydrogen (H2) concentration measurements in dogs on 3 consecutive days after introduction of a new diet.
  
  
  METHODS
  10 healthy colony-source dogs. Procedure Dogs were fed a commercial pet food for a minimum of 10 days before introduction of a high-carbohydrate commercial diet. Expired breath samples were collected at baseline and every 90 minutes for 18 hours on the first 3 days after introduction of the new diet. The area under the curve (AUC) for breath H2 concentration versus time on days 1, 2, and 3 were compared by use of repeated-measures ANOVA.
  
  
  RESULTS
  The (AUC) did not differ significantly among test days 1, 2, and 3.
  
  
  CONCLUSIONS
  Expired breath H2 concentration in dogs indicated good reproducibility during the first 3 days after introduction of a new diet.
  
  
  CONCLUSIONS
  It is not necessary to provide a period for adaptation to a test diet prior to performing breath H2 tests in dogs.
authors.affiliation: Department of Veterinary Clinical Sciences, Massey University, Palmerston North, New Zealand.
authors.forename: S A
authors.initials: SA
authors.lastname: Bissett
authors.forename: A
authors.initials: A
authors.lastname: Spohr
authors.forename: W G
authors.initials: WG
authors.lastname: Guilford
authors.forename: S J
authors.initials: SJ
authors.lastname: Haslett
mesh_terms: D000821:Animal Feed; D000818:Animals; D001944:Breath Tests / Q000379:methods*; D002415:Cats; D004032:Diet; D004063:Digestion; D004285:Dogs; D006859:Hydrogen / Q000032:analysis*; D015203:Reproducibility of Results; D013997:Time Factors
chemical_list: D006859:Hydrogen