Arugosin F: a new antifungal metabolite from the coprophilous fungus Ascodesmis sphaerospora.
Chemical studies of the coprophilous fungus Ascodesmis sphaerospora (JS 247) have led to the isolation of arugosin F (1), a new antifungal and antibacterial metabolite. The structure was determined based on NMR and MS data and on comparison with data for known members of the arugosin class. A known xanthone (2) was also isolated.
Hein
S M
SM
Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.
Gloer
J B
JB
Koster
B
B
Malloch
D
D
D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D001203:Ascomycota / Q000737:chemistry*; D001584:Benzoxepins / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry
D000935:Antifungal Agents; D001584:Benzoxepins; C117239:arugosin F