title: In vivo radiolabel quantification in small-animal models.
abstract: Current developments in emission tomography especially designed for small-animal imaging are presented. Adaptations of the human tomography principles take advantage of the smaller field of view to achieve about 2-mm usable resolution. Some evaluations in rat tomography are presented, and the problems of limiting resolution of PET and SPECT systems are discussed. Finally, a new approach that more specifically takes into account the parameters induced by in vivo quantification in rodents is presented.
authors.affiliation: Institut de Physique Nucléaire, Orsay, France.
authors.forename: L
authors.initials: L
authors.lastname: Ploux
authors.forename: R
authors.initials: R
authors.lastname: Mastrippolito
mesh_terms: D000818:Animals; D001921:Brain / Q000000981:diagnostic imaging*; D015902:Gamma Cameras; D019275:Radiopharmaceuticals / Q000032:analysis*; D051381:Rats; D014055:Tomography, Emission-Computed / Q000295:instrumentation*; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation*
chemical_list: D019275:Radiopharmaceuticals