Campylobacter jejuni bacteremia and Guillain-Barré syndrome in a renal transplant recipient.
In patients who have not undergone transplantation, Guillain-Barré syndrome (GBS) is typically preceded by an acute infection often sustained by Campylobacter jejuni. Thus far, in renal transplant recipients, only eight cases of GBS have been reported. In seven patients GBS was attributed to cytomegalovirus infection and in the eighth patient to cyclosporin A neurotoxicity. We report here the case of a GBS in a renal transplant recipient following C. jejuni bacteremia. The infection quickly disappeared after erythromycin and methronidazole therapy. GBS progressively evolved into a paraparesis within 1 week. After reaching a plateau phase, the clinical status improved and the patient was able to walk unassisted after 3 weeks. At this last check-up, 54 months later, the patient was doing well with a functioning graft and only minimal weakness of the lower limbs.
Maccario
M
M
Division of Nephrology and Dialysis, IRCCS Ospedale Maggiore, Milan, Italy.
Tarantino
A
A
Nobile-Orazio
E
E
Ponticelli
C
C
D016470:Bacteremia / Q000150:complications / Q000209:etiology*; D002169:Campylobacter Infections / Q000150:complications / Q000209:etiology*; D016123:Campylobacter jejuni; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011129:Polyradiculoneuropathy / Q000209:etiology*