title: Intraoperative transmission of blood-borne disease in haemophilia.
abstract: Because HIV and hepatitis B and C infection can be transmitted by exposure to infected blood or blood components, orthopaedists are at risk for HIV and hepatitis infection during surgical procedures. Thus, care must be taken to protect themselves from transmission of HIV and the hepatitis virus. The following precautions are recommended: double latex gloves, changed hourly, or a combination of cloth and latex gloves, enclosed hood and face-masks and operative isolator with umbilical-cord aspirator; knee-length impermeable gowns of high-count polyester weave or plastic-lined nonwoven spun-lace polyester; a combination of shoe-covers that provide waterproof coverage as high as the knee; and disposable drapes. If a member of the operating team is inadvertently pricked or cut, the wound should be washed immediately with iodine, soap and water. If the injured person has been immunized for the hepatitis B (and has adequate titres), or is positive for hepatitis B surface antigen or antibody, no further treatment is necessary. Otherwise, two doses of hepatitis B immune globulin should be given, 5 mL immediately and 5 mL after 1 month. Because HIV infection can be transmitted by exposure to infected blood, orthopaedic surgeons are also at risk for HIV infection. Prospective studies suggest that this risk is very low; nevertheless, healthcare workers need to adhere rigorously to the aforementioned infection-control precautions to minimize the risk of exposure to blood.
authors.affiliation: International Hemophilia Training Center of the WFH, La Paz University Hospital, Madrid, Spain.
authors.forename: E C
authors.initials: EC
authors.lastname: Rodriguez-Merchan
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000635:transmission*; D006467:Hemophilia A / Q000150:complications / Q000628:therapy*; D006525:Hepatitis, Viral, Human / Q000635:transmission*; D006801:Humans; D007431:Intraoperative Complications; D009985:Orthopedics; D012307:Risk Factors; D065227:Transfusion Reaction