Role of electron microscopy in the evaluation of soft tissue neoplasms, with emphasis on spindle cell and pleomorphic tumors.
The current significant role of transmission electron microscopy in the evaluation of soft tissue tumors when correlated with conventional histological and immunohistochemical studies is discussed for the following entities: myxofibrosarcoma, storiform-pleomorphic fibrosarcoma (malignant fibrous histiocytoma), and myofibrosarcoma; dermatofibrosarcoma protuberans; hemangiopericytoma; monophasic synovial sarcoma; extrarenal rhabdoid tumor; soft tissue perineurioma; and gastrointestinal stromal tumors, notably the so-called autonomic nerve variant.
Erlandson
R A
RA
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Woodruff
J M
JM
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism; D002675:Child, Preschool; D005260:Female; D005347:Fibroblasts / Q000378:metabolism / Q000648:ultrastructure; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D006393:Hemangiopericytoma / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D007120:Immunochemistry; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D018218:Neoplasms, Fibrous Tissue / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D018335:Rhabdoid Tumor / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D013584:Sarcoma, Synovial / Q000175:diagnosis / Q000378:metabolism / Q000648:ultrastructure; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000648:ultrastructure*; D017154:Stromal Cells / Q000378:metabolism / Q000648:ultrastructure
D014408:Biomarkers, Tumor