title: Selective photocleavage of single-stranded nucleic acids by cyclobisintercaland molecules.
abstract: Irradiation of mixtures of a single-stranded circular plasmid and of a double-stranded supercoiled DNA in presence of the cyclobisintercaland compounds 2 or 3 shows that these reagents effect the selective photocleavage of the single-stranded entity. Furthermore, 2 also cleaves tRNAasp preferentially at single-stranded domains.
authors.affiliation: Laboratoire de Chimie Supramoléculaire, ISIS, Université Louis Pasteur, Strasbourg, France.
authors.forename: A J
authors.initials: AJ
authors.lastname: Blacker
authors.forename: M P
authors.initials: MP
authors.lastname: Teulade-Fichou
authors.forename: J P
authors.initials: JP
authors.lastname: Vigneron
authors.forename: M
authors.initials: M
authors.lastname: Fauquet
authors.forename: J M
authors.initials: JM
authors.lastname: Lehn
mesh_terms: D004277:DNA, Single-Stranded / Q000378:metabolism* / Q000528:radiation effects; D004278:DNA, Superhelical / Q000378:metabolism; D004587:Electrophoresis, Agar Gel; D008956:Models, Chemical; D008958:Models, Molecular; D009690:Nucleic Acid Conformation / Q000187:drug effects / Q000528:radiation effects; D010777:Photochemistry; D010957:Plasmids / Q000378:metabolism; D012313:RNA / Q000378:metabolism* / Q000528:radiation effects
chemical_list: D004277:DNA, Single-Stranded; D004278:DNA, Superhelical; D012313:RNA