Radio-opaque markers for stereotactic imaging of uveal melanoma.
In in vitro and in vivo studies, episclerally sutured radio-opaque markers were evaluated as localizers for better determination of the clinical tumour volume prior to stereotactic radio-therapy of uveal melanoma. Four different types of markers were studied in vitro: tantalum marker, 2.5 mm in diameter; ring-shaped markers custom-designed in polymethyl methacrylate (PMMA), 2.6 mm and 3.0 mm in diameter; and barium-impregnated silicone rubber spheres, 2 mm in diameter. In vivo PMMA markers 3.0 mm in diameter and barium-impregnated silicone rubber spheres 2 mm in diameter were used. The best results were obtained with the barium-impregnated silicone rubber spheres both in vitro and in vivo. For the CT-delineation of selected uveal melanomas with either a flat discoid shape or flat tumour extensions or when adjacent serous retinal detachment is present, small episclerally sutured barium-impregnated silicone rubber spheres are useful as localizers for determining the clinical tumour volume.
Zehetmayer
M
M
Department of Ophthalmology, University Hospital of Vienna, Austria.
Schima
W
W
Menapace
R
R
Kitz
K
K
Radner
W
W
Dieckmann
K
K
D006801:Humans; D007089:Image Enhancement; D008545:Melanoma / Q000000981:diagnostic imaging*; D008670:Metals; D019904:Polymethyl Methacrylate; D013238:Stereotaxic Techniques; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014604:Uveal Neoplasms / Q000000981:diagnostic imaging*
D008670:Metals; D019904:Polymethyl Methacrylate