title: Constituents and bioactive principles of Polygonum chinensis.
abstract: Isolation and characterization of the chemical constituents of Polygonum chinensis L. gave the new 25R-spirost-4-ene-3,12-dione. The known compounds stigmast-4-ene-3,6-dione, stigmastane-3,6-dione, hecogenin and aurantiamide acetate were also isolated from for the first time from this species. Their anti-inflammatory and anti-allergic properties are described.
authors.affiliation: Graduate Institute of Pharmaceutical Chemistry, China Medical College, Taichung, Taiwan, R.O.C.
authors.forename: P L
authors.initials: PL
authors.lastname: Tsai
authors.forename: J P
authors.initials: JP
authors.lastname: Wang
authors.forename: C W
authors.initials: CW
authors.lastname: Chang
authors.forename: S C
authors.initials: SC
authors.lastname: Kuo
authors.forename: P D
authors.initials: PD
authors.lastname: Chao
mesh_terms: D000818:Animals; D018926:Anti-Allergic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002783:Cholestenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004151:Dipeptides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008407:Mast Cells / Q000187:drug effects; D015394:Molecular Structure; D010946:Plants, Medicinal; D051381:Rats; D017207:Rats, Sprague-Dawley; D012502:Sapogenins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013057:Spectrum Analysis; D013150:Spirostans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C116554:25-spirost-4-ene-3,12-dione; D018926:Anti-Allergic Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D002783:Cholestenones; D004151:Dipeptides; D012502:Sapogenins; D013150:Spirostans; C017726:stigmast-4-ene-3,6-dione; C007908:hecogenin; C011670:N-benzoylphenylalanylphenylalinol acetate