title: Locally focused MRI of interventions.
abstract: Certain interventional MR procedures would benefit from T2-weighted imaging because of the sensitivity of T2-weighted images to tissue damage and target lesion contrast. To acquire such images with reasonable temporal resolution, a single-shot acquisition should be used because of the inherently long TR needed for T2 weighting. Unfortunately, most scanners require long readout times (eg, greater than 150 msec) and high bandwidths (eg, greater than 120 kHz) to perform conventional single-shot imaging with high spatial resolution. The resulting images are thus degraded by unacceptable artifacts and noise levels. This study illustrates how to create locally focused MR images that have high spatial resolution in a region of interest and lower spatial resolution elsewhere in the image. Because these images can be created from sparse k-space data, a scanner with modest gradients (eg, 10 mT/m maximal amplitude, 500 microsec minimal rise time) can acquire them after a single excitation with relatively short readout time and low bandwidth. This technique may make it practical to monitor interventions with T2-weighted imaging. The method was illustrated by reconstructing dynamic changes, which were simulated experimentally by moving objects in the vicinity of a normal human head.
authors.affiliation: Department of Radiology, Goldblatt MRI Center, University of Chicago, IL 60637, USA. vkuperma@midway.uchicago.edu
authors.forename: V Y
authors.initials: VY
authors.lastname: Kuperman
authors.forename: S K
authors.initials: SK
authors.lastname: Nagle
authors.forename: D N
authors.initials: DN
authors.lastname: Levin
mesh_terms: D001921:Brain / Q000033:anatomy & histology*; D003198:Computer Simulation; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019047:Phantoms, Imaging; D012016:Reference Values; D012680:Sensitivity and Specificity