title: Combination therapy of resistant warts in a patient with AIDS.
abstract: BACKGROUND
  An AIDS patient on anti-HIV therapy consisting of two reverse transcriptase inhibitors had a low CD4+ lymphocyte count, a high HIV viral RNA load, and facial warts that were resistant to ablative therapy.
  
  
  OBJECTIVE
  To find a regimen to treat resistant warts in an AIDS patient with a depressed CD4 count and high HIV viral load.
  
  
  METHODS
  A protease inhibitor was added to his regimen and he was treated with ablative therapy using a 585 nm flashlamp-pumped pulsed dye laser (FPPDL).
  
  
  RESULTS
  Observed resolution of the warts one month later, with no recurrence at seven-month follow-up.
  
  
  CONCLUSIONS
  Treatment of resistant warts in patients with AIDS may be enhanced by triple-drug therapy which includes a protease inhibitor, used in combination with ablative therapy, such as the FPPDL.
authors.affiliation: Department of Dermatology, University of Texas Southwestern Medical Center, Dallas 75235-9069, USA.
authors.forename: T R
authors.initials: TR
authors.lastname: Roark
authors.forename: A G
authors.initials: AG
authors.lastname: Pandya
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000628:therapy*; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D006801:Humans; D053685:Laser Therapy; D008047:Lip Diseases / Q000628:therapy; D008297:Male; D008875:Middle Aged; D014860:Warts / Q000628:therapy*
chemical_list: D019380:Anti-HIV Agents