[Homologous lamellar central limbokeratoplasty in severe limbal stem cell deficiency].
OBJECTIVE
It is the purpose of this case report to present a new surgical technique for treatment of severe limbal stem cell deficiency.


METHODS
In a 42-year-old female patient with conjunctivalization of the cornea in congenital aniridia a homologous lamellar central limbokeratoplasty was performed. Postoperatively systemic Ciclosporin A was administered in order to prevent the transplanted limbal stem cells from immunological destruction. During the follow-up period of 16 months no immune reaction against the transplanted limbal stem cells could be observed. Visual acuity was ameliorated considerably.


CONCLUSIONS
Homologous lamellar central limbokeratoplasty is a promising surgical procedure in selected patients with severe limbal stem cell deficiency having less complications compared with penetrating central limbokeratoplasty.
Sundmacher
R
R
Augenklinik der Heinrich-Heine-Universität, Düsseldorf.
Reinhard
T
T
D000328:Adult; D015783:Aniridia / Q000473:pathology* / Q000601:surgery*; D016039:Corneal Transplantation / Q000379:methods* / Q000473:pathology; D016572:Cyclosporine / Q000627:therapeutic use; D005260:Female; D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D016850:Limbus Corneae / Q000473:pathology*; D013234:Stem Cells / Q000473:pathology*; D014184:Transplantation, Homologous
D016572:Cyclosporine
Homologe lamelläre zentrale Limbokeratoplasik bei schwerer Limbusstammzellinsuffizienz.