title: Treatment of acute deep vein thrombosis in spinal cord injured patients with enoxaparin: a cost analysis.
abstract: Enoxaparin, a low molecular weight heparin, has been demonstrated to be effective in the prophylaxis and treatment of deep vein thrombosis (DVT) in the general population. This study presents an analysis of the costs of subcutaneous (SQ) enoxaparin compared with intravenous (IV) heparin. Data were gathered on six spinal cord injured (SCI) patients in an acute freestanding rehabilitation center who were initially treated with SQ enoxaparin (n=3) or IV heparin (n=3) for a proximal DVT. No patients in either group developed further clinical complications. Comparison of the total costs of each treatment was performed, including the direct cost of the drug, as well as some of the costs of administration. Although the cost of enoxaparin per unit dose is higher, the total costs of enoxaparin are slightly lower, because its labor and administration costs are less. Subcutaneous enoxaparin is a safe, cost-effective, and less labor-intensive treatment, and can be of substantial benefit in the treatment of DVT in SCI patients in the rehabilitation setting.
authors.affiliation: UMDNJ/New Jersey Medical School, Newark, USA.
authors.forename: A
authors.initials: A
authors.lastname: Tomaio
authors.forename: S C
authors.initials: SC
authors.lastname: Kirshblum
authors.forename: K C
authors.initials: KC
authors.lastname: O'Connor
authors.forename: M
authors.initials: M
authors.lastname: Johnston
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage / Q000191:economics*; D003362:Cost-Benefit Analysis; D003365:Costs and Cost Analysis; D017984:Enoxaparin / Q000008:administration & dosage / Q000191:economics*; D005260:Female; D006493:Heparin / Q000008:administration & dosage / Q000191:economics; D006801:Humans; D007262:Infusions, Intravenous; D007279:Injections, Subcutaneous; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012047:Rehabilitation Centers / Q000191:economics; D012189:Retrospective Studies; D013119:Spinal Cord Injuries / Q000150:complications / Q000191:economics*; D013924:Thrombophlebitis / Q000188:drug therapy / Q000191:economics*
chemical_list: D000925:Anticoagulants; D017984:Enoxaparin; D006493:Heparin