Interrelationship of viruses and cells. The cytopathic property of adenoviruses.
The application of in vitro cell cultures in virus research has a great importance in studies on the interaction between virus and cell. A great number of the viruses causes characteristic degeneration in the infected cells, well visible in the light-microscope, and due to their cytopathic effect the existence of viruses became directly detectable. Based on characteristic changes even the serological type of virus can be determined in some cases. Thus the multilateral examination of the interaction between virus and host cell has immense importance both in virus research and in therapy.
Nász
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Microbiology-Virology Research Group of Hungarian Academy of Sciences, Budapest, Hungary.
Lengyel
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D000260:Adenoviruses, Human / Q000502:physiology*; D000818:Animals; D003588:Cytopathogenic Effect, Viral