title: Localization of lamins in mammalian spermatozoa.
abstract: Little information is available concerning lamins in the nucleus of germinal cells. In this paper we briefly describe and compare the organization of A- and B-type lamins in several mammalian spermatozoa. Nuclear lamin B is localized primarily in the postacrosomal sheath of human, bull and rabbit spermatozoa; lamin A/C is a major component of the equatorial segment in most of mammalian sperm, with the exception of rodents. In mouse sperm, devoid of equatorial segment, only lamin B appears to be expressed. The same happens in human pathological spermatozoa in which the equatorial segment is altered or absent.
authors.affiliation: Department of Cellular and Molecular Biology, Northwestern University Medical School, Chicago, IL, USA.
authors.forename: R D
authors.initials: RD
authors.lastname: Goldman
authors.forename: B
authors.initials: B
authors.lastname: Baccetti
authors.forename: G
authors.initials: G
authors.lastname: Collodel
authors.forename: L
authors.initials: L
authors.lastname: Gambera
authors.forename: E
authors.initials: E
authors.lastname: Moretti
authors.forename: P
authors.initials: P
authors.lastname: Piomboni
mesh_terms: D000818:Animals; D006801:Humans; D034904:Lamin Type A; D034921:Lamin Type B; D034882:Lamins; D008297:Male; D051379:Mice; D008854:Microscopy, Electron; D009687:Nuclear Proteins / Q000648:ultrastructure*; D011817:Rabbits; D013094:Spermatozoa / Q000648:ultrastructure*
chemical_list: D034904:Lamin Type A; D034921:Lamin Type B; D034882:Lamins; D009687:Nuclear Proteins