A case-control study of the relationship between dietary factors and risk of lung cancer in women of Shenyang, China.
A 1:1 case-control study of lung cancer incidence among women in Shenyang was conducted to explore the relationship between diet and the risk of lung cancer, with emphasis on the potential effects of a list of specific dietary constituents on modifying lung cancer risks. Dietary information on 290 cases and population-matched controls was obtained by personal interviews. Multiple logistic regression models were used for the statistical analysis and summarization of the data. A significant difference was found between cases and controls with respect to intake of beta-carotene, vitamin C and fibers, all of which reduced the risk for lung cancer in a dose-dependent manner; yielding calculated odds ratio (OR) of 0.84, 0.75, and 0.46, respectively. The apparent effects of these nutrients persisted after adjusting for cigarette smoking;suggesting that they may function as protective factors to reduce the risk for lung cancer in Chinese women.
Zhou
B
B
Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY 10595, USA.
Wang
T
T
Sun
G
G
Guan
P
P
Wu
J M
JM
D000328:Adult; D000368:Aged; D016588:Anticarcinogenic Agents / Q000494:pharmacology; D001205:Ascorbic Acid / Q000494:pharmacology; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D004032:Diet; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004043:Dietary Fiber / Q000494:pharmacology; D004044:Dietary Proteins; D002149:Energy Intake; D005260:Female; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008175:Lung Neoplasms / Q000453:epidemiology*; D008875:Middle Aged; D012643:Selenium; D012907:Smoking / Q000453:epidemiology; D014815:Vitamins; D019207:beta Carotene / Q000494:pharmacology
D016588:Anticarcinogenic Agents; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004043:Dietary Fiber; D004044:Dietary Proteins; D014815:Vitamins; D019207:beta Carotene; D012643:Selenium; D001205:Ascorbic Acid