title: MIPS: a database for genomes and protein sequences.
abstract: The Munich Information Center for Protein Sequences (MIPS-GSF), Martinsried near Munich, Germany, develops and maintains genome oriented databases. It is commonplace that the amount of sequence data available increases rapidly, but not the capacity of qualified manual annotation at the sequence databases. Therefore, our strategy aims to cope with the data stream by the comprehensive application of analysis tools to sequences of complete genomes, the systematic classification of protein sequences and the active support of sequence analysis and functional genomics projects. This report describes the systematic and up-to-date analysis of genomes (PEDANT), a comprehensive database of the yeast genome (MYGD), a database reflecting the progress in sequencing the Arabidopsis thaliana genome (MATD), the database of assembled, annotated human EST clusters (MEST), and the collection of protein sequence data within the framework of the PIR-International Protein Sequence Database (described elsewhere in this volume). MIPS provides access through its WWW server (http://www.mips.biochem.mpg.de) to a spectrum of generic databases, including the above mentioned as well as a database of protein families (PROTFAM), the MITOP database, and the all-against-all FASTA database.
authors.affiliation: GSF-Forschungszentrum für Umwelt und Gesundheit, Munich Information Center for Protein Sequences, am Max-Planck-Instut für Biochemie, Am Klopferspitz 18, D-82152 Martinsried, Germany. mewes@mips.biochem.mpg.de
authors.forename: H W
authors.initials: HW
authors.lastname: Mewes
authors.forename: K
authors.initials: K
authors.lastname: Heumann
authors.forename: A
authors.initials: A
authors.lastname: Kaps
authors.forename: K
authors.initials: K
authors.lastname: Mayer
authors.forename: F
authors.initials: F
authors.lastname: Pfeiffer
authors.forename: S
authors.initials: S
authors.lastname: Stocker
authors.forename: D
authors.initials: D
authors.lastname: Frishman
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017360:Arabidopsis / Q000235:genetics; D016208:Databases, Factual; D020224:Expressed Sequence Tags; D016678:Genome; D016681:Genome, Fungal; D015894:Genome, Human; D018745:Genome, Plant; D005858:Germany; D006801:Humans; D016247:Information Storage and Retrieval; D005810:Multigene Family; D011506:Proteins / Q000737:chemistry* / Q000235:genetics; D015003:Yeasts / Q000235:genetics
chemical_list: D011506:Proteins