Mechanism of emergence of hepatitis B virus escape variants: approaches to prevention.
Hepatitis B virus causes a chronic infection in a large proportion of cases. One possible mechanism whereby hepatitis B avoids the host defences is by mutation of antigenic epitopes. This article reviews current views in the area.
Thomas
H C
HC
Department of Medicine A, Imperial College School of Medicine, London, UK.
D015195:Drug Design; D006509:Hepatitis B / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D017325:Hepatitis B Vaccines / Q000276:immunology*; D006515:Hepatitis B virus / Q000235:genetics* / Q000276:immunology*; D006801:Humans; D009154:Mutation
D017325:Hepatitis B Vaccines