title: Fast numerical algorithms for fitting multiresolution hybrid shape models to brain MRI.
abstract: In this paper, we present new and fast numerical algorithms for shape recovery from brain MRI using multiresolution hybrid shape models. In this modeling framework, shapes are represented by a core rigid shape characterized by a superquadric function and a superimposed displacement function which is characterized by a membrane spline discretized using the finite-element method. Fitting the model to brain MRI data is cast as an energy minimization problem which is solved numerically. We present three new computational methods for model fitting to data. These methods involve novel mathematical derivations that lead to efficient numerical solutions of the model fitting problem. The first method involves using the nonlinear conjugate gradient technique with a diagonal Hessian preconditioner. The second method involves the nonlinear conjugate gradient in the outer loop for solving global parameters of the model and a preconditioned conjugate gradient scheme for solving the local parameters of the model. The third method involves the nonlinear conjugate gradient in the outer loop for solving the global parameters and a combination of the Schur complement formula and the alternating direction-implicit method for solving the local parameters of the model. We demonstrate the efficiency of our model fitting methods via experiments on several MR brain scans.
authors.affiliation: Department of Computer & Information Science & Engineering, University of Florida, Gainesville 32611, USA. vemuri@cise.ufl.edu
authors.forename: B C
authors.initials: BC
authors.lastname: Vemuri
authors.forename: Y
authors.initials: Y
authors.lastname: Guo
authors.forename: S H
authors.initials: SH
authors.lastname: Lai
authors.forename: C M
authors.initials: CM
authors.lastname: Leonard
mesh_terms: D000465:Algorithms; D019412:Anatomy, Cross-Sectional; D001921:Brain / Q000033:anatomy & histology*; D003198:Computer Simulation; D006801:Humans; D008279:Magnetic Resonance Imaging