Reversible ischemia determined by xenon-enhanced CT after 90 minutes of complete basilar artery occlusion.
Intraarterial thrombolytic therapy decreases mortality in the treatment of acute basilar artery occlusion. An acute decrease in cerebral blood flow (CBF) (<12 mL/100 g per minute) has been reported to invariably result in infarction. We report a case of acute basilar artery occlusion, recanalized within 90 minutes, with reversal of CBF of less than 6 mL/100 g per minute. After reperfusion, areas with persistent CBF of 6 mL/100 g per minute resulted in infarctions on subsequent CT studies. Parenchymal viability is possible after 90 minutes of posterior CBF of 6 mL/100 g per minute.
Levy
E I
EI
Department of Neurological Surgery, Presbyterian University Hospital, The University of Pittsburgh Medical Center, PA 15213, USA.
Scarrow
A M
AM
Kanal
E
E
Rubin
G
G
Yonas
H
H
Kirby
L
L
D000208:Acute Disease; D001921:Brain / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002560:Cerebrovascular Circulation; D003287:Contrast Media; D006801:Humans; D008297:Male; D008875:Middle Aged; D015912:Thrombolytic Therapy; D014057:Tomography, X-Ray Computed; D014715:Vertebrobasilar Insufficiency / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000503:physiopathology; D014978:Xenon
D003287:Contrast Media; D014978:Xenon