title: MitBASE pilot: a database on nuclear genes involved in mitochondrial biogenesis and its regulation in Saccharomyces cerevisiae.
abstract: In the framework of the EU BIOTECH PROGRAM and within the 'MITBASE: a comprehensive and integrated database on mtDNA' project, we have prepared a pilot database (MitBASE Pilot) on nuclear genes involved in mitochondrial biogenesis and its regulation in Saccharomyces cerevisiae. MitBASE Pilot includes nuclear genes encoding mitochondrial proteins as well as nuclear genes encoding products which are localised in other sub-cellular compartments but nevertheless interact with mitochondrial functions. Genes have been classified on the basis of the mitochondrial process in which they participate and the mitochondrial phenotype of the gene knockout. The structure of the MitBASE Pilot database has been conceived for a flexible organisation of the information. An intuitive visual query system has been developed which allows users to select information in different combinations, both in the query and the output format, according to their needs. MitBASE Pilot is a relational database, is maintained at the EMBL-European Bioinformatics Institute (EBI) and is available at the World Wide Web site http://www3.ebi.ac. uk/Research/Mitbase/mitbiog.pl
authors.affiliation: Consiglio Nazionale delle Ricerche, Centro di Studio sui Mitocondri e Metabolismo Energetico, presso Università di Bari, via Amendola 165/A, I-70126 Bari, Italy.
authors.forename: B
authors.initials: B
authors.lastname: de Pinto
authors.forename: S B
authors.initials: SB
authors.lastname: Malladi
authors.forename: N
authors.initials: N
authors.lastname: Altamura
mesh_terms: D002467:Cell Nucleus / Q000235:genetics; D016208:Databases, Factual; D005656:Fungal Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal / Q000235:genetics*; D016247:Information Storage and Retrieval; D020407:Internet; D008928:Mitochondria / Q000235:genetics / Q000502:physiology*; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000254:growth & development
chemical_list: D005656:Fungal Proteins