title: Identification of N2-(1-carboxymethyl)guanine (CMG) as a guanine advanced glycation end product.
abstract: The reaction of D-glucose with 9-methylguanine produces N2-fructosyl-9-methylguanine, which undergoes oxidation to produce N2-(1-carboxymethyl)-9-methylguanine as a major adduct.
authors.affiliation: Picower Institute for Medical Research, Manhasset, NY 11030, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: al-Abed
authors.forename: E
authors.initials: E
authors.lastname: Schleicher
authors.forename: W
authors.initials: W
authors.lastname: Voelter
authors.forename: H
authors.initials: H
authors.lastname: Liebich
authors.forename: A
authors.initials: A
authors.lastname: Papoulis
authors.forename: R
authors.initials: R
authors.lastname: Bucala
mesh_terms: D005947:Glucose / Q000737:chemistry*; D017127:Glycation End Products, Advanced / Q000032:analysis / Q000737:chemistry*; D006147:Guanine / Q000031:analogs & derivatives* / Q000737:chemistry; D007202:Indicators and Reagents; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D017127:Glycation End Products, Advanced; D007202:Indicators and Reagents; C116702:N(2)-(1-carboxymethyl)guanine; C116701:9-methylguanine; D006147:Guanine; D005947:Glucose