Anthelmintic beta-hydroxyketoamides (BKAs).
We have prepared several anthelmintic coumarins based on the beta-hydroxyketoamide (BKA) template and have shown that this template remains valid over a wide range of changes to the coumarin moiety allowing for the inclusion of carbocyclic, bicyclic, and heterocyclic rings.
Lee
B H
BH
Animal Health Discovery Research, Pharmacia & Upjohn, Inc., Kalamazoo, MI 49001, USA.
Clothier
M F
MF
Dutton
F E
FE
Conder
G A
GA
Johnson
S S
SS
D000818:Animals; D000871:Anthelmintics / Q000138:chemical synthesis* / Q000494:pharmacology; D003374:Coumarins / Q000138:chemical synthesis* / Q000494:pharmacology; D005849:Gerbillinae
D000871:Anthelmintics; D003374:Coumarins