title: [Management of severe infection complicating aortofemoral grafts].
abstract: OBJECTIVE
  Infection of the retroperitoneum after implantation of an abdomino-femoral aortic graft remains one of the main problems in vascular surgery. On basis of a critical review of own experiences we evaluated the management of this difficult clinical situation.
  
  
  METHODS
  From 1970-1996 1500 aortofemoral graft operations (aneurysmal disease: 512, aortoiliacal occlusive disease: 988) were performed. Abdominal infection occurred in 12 patients (0.8%) (12 men, median age 60.5 [48-80] years).
  
  
  RESULTS
  The median interval between operation and infection was 17.7 (0.5-108) months. The port of infection was in 50% the groin, 25% suffered from abdominal infection, in 3 cases it was not to identify. Clinical manifestation of infection was aortoduodenal fistula in 2 patients, false aneurysms in 2 cases, and a paraprosthetic abscess in another 4 patients. Operative therapy comprised (partial) removal of infected material in 10 patients with consecutive extraanatomical reconstruction in 8 of these. Mortality of graft infection was 50%. Causes of death were untreatable sepsis in 4 patients, another 2 died from hemorrhagic shock. 3 out of 6 surviving patients finally lost their limbs following multiple vascular procedures.
  
  
  CONCLUSIONS
  Adequate surgical therapy of infected aortofemoral grafts remains an unsolved problem. Lack of knowledge of suitable parameters for the best treatment leaves the outcome of prosthetic infection unpredictable. Removal of the infected graft with extraanatomic reconstruction seems to be the standard of surgical treatment, which is recommended in these cases.
authors.affiliation: Klinische Abteilung für Gefässchirurgie, Universität Wien, Osterreich.
authors.forename: J
authors.initials: J
authors.lastname: Karner-Hanusch
authors.forename: M
authors.initials: M
authors.lastname: Staudacher
authors.forename: M
authors.initials: M
authors.lastname: Prager
authors.forename: G
authors.initials: G
authors.lastname: Kretschmer
authors.forename: P
authors.initials: P
authors.lastname: Polterauer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D005263:Femoral Artery / Q000601:surgery; D006801:Humans; D007239:Infections / Q000209:etiology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged
vernacular_title: Management der tiefen Infektion als Komplikation nach Bifurkationsprothese.