title: Further observations of true mosaic trisomy 17 ascertained in amniotic fluid cell cultures.
abstract: Three new cases of true mosaic trisomy 17 (MT17) were diagnosed in amniotic fluid cells. Postnatal chromosome analysis from lymphocytes did not confirm the trisomic cell line, and follow-up studies showed normal psycho-motor development of the children, in one case up to the age of 4 1/2 years. We suggest that there are similarities between MT17 and MT20, in which the majority of pregnancies result in deliveries of healthy babies.
authors.affiliation: Abteilung Medizinische Genetik, Universität, Ulm, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Djalali
authors.forename: G
authors.initials: G
authors.lastname: Barbi
authors.forename: J
authors.initials: J
authors.lastname: Mueller-Navia
authors.forename: M
authors.initials: M
authors.lastname: Schneider
authors.forename: U
authors.initials: U
authors.lastname: Tettenborn
authors.forename: U
authors.initials: U
authors.lastname: Trautmann
authors.forename: R
authors.initials: R
authors.lastname: Ulmer
authors.forename: M
authors.initials: M
authors.lastname: Wolf
authors.forename: W
authors.initials: W
authors.lastname: Vogel
mesh_terms: D000328:Adult; D000649:Amniocentesis; D000653:Amniotic Fluid / Q000166:cytology*; D002478:Cells, Cultured; D002886:Chromosomes, Human, Pair 17; D005260:Female; D005865:Gestational Age; D006801:Humans; D008297:Male; D009030:Mosaicism; D011247:Pregnancy; D011256:Pregnancy Outcome; D011296:Prenatal Diagnosis; D014314:Trisomy