Inhibition of cholesterol absorption by plant sterols for mass intervention.
Plant sterols and stanols lower serum cholesterol by inhibiting intestinal absorption of cholesterol. Because of their safety and efficacy, their application for mass intervention is promising. The use of fatty acid esters of stanols is particularly helpful because stanols readily mix with dietary fats in this form and their hypocholesterolemic efficacy is greater than in the free form.
Ikeda
I
I
Laboratory of Nutrition Chemistry, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
Sugano
M
M
D000818:Animals; D001161:Arteriosclerosis / Q000150:complications / Q000517:prevention & control; D008078:Cholesterol, LDL / Q000097:blood*; D003327:Coronary Disease / Q000097:blood / Q000150:complications / Q000517:prevention & control*; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications / Q000188:drug therapy; D010944:Plants / Q000737:chemistry*; D013261:Sterols / Q000009:adverse effects / Q000302:isolation & purification / Q000627:therapeutic use*
D008078:Cholesterol, LDL; D013261:Sterols