[Experimental study on prevention and treatment of neuroma by implanting nerve stump into muscle].
Prevention and treatment of traumatic neuroma by implanting the proximal neural stump into the muscle were studied. Sixteen SD rats were used for the experimental study. The proximal stump of the left sciatic nerve was implanted into the nearby muscle as the experiment side, whereas the proximal stump of the right sciatic nerve was left untreated as the control side. The results were assessed with histological and electrophysiological methods. The experiment demonstrated that neuroma was formed in the control side one month postoperatively, whereas in the experimental side the nerve fibers were dispersed among the muscle fibers and no definite neuroma was formed. Implantation of neural stump into muscle could prevent and treat traumatic neuroma.
Zhang
B
B
Department of Orthopedic Surgery, General Hospital of PLA, Beijing, P. R. China.
Guo
Y
Y
Liang
Y
Y
D000818:Animals; D005260:Female; D008297:Male; D018482:Muscle, Skeletal / Q000601:surgery; D009380:Neoplasms, Nerve Tissue / Q000209:etiology / Q000517:prevention & control*; D016067:Nerve Transfer; D009463:Neuroma / Q000209:etiology / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012584:Sciatic Nerve / Q000601:surgery*