title: Principles of epidemiological research on adverse and beneficial drug effects.
authors.affiliation: Boston Collaborative Drug Surveillance Program, Boston University Medical Center, Lexington, MA 02173, USA.
authors.forename: H
authors.initials: H
authors.lastname: Jick
authors.forename: L A
authors.initials: LA
authors.lastname: García Rodríguez
authors.forename: S
authors.initials: S
authors.lastname: Pérez-Gutthann
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems / Q000706:statistics & numerical data*; D015982:Bias; D015340:Epidemiologic Research Design; D006801:Humans; D015203:Reproducibility of Results