Novel euglycemic and hypolipidemic agents: Part-2. Antioxidant moiety as structural motif.
Several thiazolidinediones having antioxidant moities in their structural motif have been synthesised and evaluated for their euglycemic and hypolipidemic activities. A few of them have been found to be superior to troglitazone.
Reddy
K A
KA
Dr. Reddy's Research Foundation, Hyderabad, India.
Lohray
B B
BB
Bhushan
V
V
Reddy
A S
AS
Kishore
P H
PH
Rao
V V
VV
Saibaba
V
V
Bajji
A C
AC
Rajesh
B M
BM
Reddy
K V
KV
Chakrabarti
R
R
Rajagopalan
R
R
D000818:Animals; D000975:Antioxidants / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001786:Blood Glucose / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy / Q000235:genetics; D015195:Drug Design; D007004:Hypoglycemic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000960:Hypolipidemic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D007202:Indicators and Reagents; D051379:Mice; D008817:Mice, Mutant Strains; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D014280:Triglycerides / Q000097:blood
D000975:Antioxidants; D001786:Blood Glucose; D007004:Hypoglycemic Agents; D000960:Hypolipidemic Agents; D007202:Indicators and Reagents; D013844:Thiazoles; D014280:Triglycerides