[Effect of tonicity of the medium on the sensitivity of Escherichia coli bacteria to gamma-quantum 60Co, ultrasound and hyperthermia].
The cell lethality and permeability induced in Escherichia coli B/r and Escherichia coli BS-1 by 60Co gamma-ray irradiation, ultrasound and hyperthermia in media containing different concentrations of NaCl have been investigated. It was shown that independently from the nature of damaging factors hypotonic media increase while hypertonic media in certain range of osmolyte concentration decrease sensitivity of cells to action of this factors. It was proposed that discovered phenomenology was caused by salt modification of status of the cell osmotic homeostasis destabilizing by ionizing radiation, ultrasound or hyperthermia and was not related with the system of dark repair of DNA.
Morozov
I I
II
Medical Radiology Research Centre, Russian Academy of Medical Sciences, Obninsk.
Petin
V G
VG
Morozova
G V
GV
D003470:Culture Media; D004260:DNA Repair; D004926:Escherichia coli / Q000502:physiology* / Q000528:radiation effects; D005720:Gamma Rays; D006706:Homeostasis / Q000502:physiology / Q000528:radiation effects; D006358:Hot Temperature; D009997:Osmotic Pressure; D010539:Permeability
D003470:Culture Media
Vliianie tonichnosti sredy na chuvstvitel'nost' bakteriĭ Escherichia coli k gamma-kvantam 60Co, ul'trazvuku i gipertermii.