Prostate cancer in the African American: is this a different disease?
Age-adjusted mortality rates from prostate cancer between 1991 and 1995 are approximately two times worse among African-American men than Caucasian men. Age-specific mortality rates from prostate cancer are reported to be three times greater among African-American men compared with Caucasian men between the ages of 40 and 60 years. These statistics lead one to ask whether the difference in outcome is secondary to a more rapidly growing prostate cancer among African-American men compared with Caucasian men, or is it a result of delayed diagnosis among African-American men, which would account for there being more advanced prostate cancer at presentation? This report demonstrates many histological and biological differences that may account for clinical outcome differences.
Powell
I J
IJ
Department of Urology, Wayne State University, Detroit, MI 48201, USA.
D001741:Black or African American; D044383:Black People; D018450:Disease Progression; D006801:Humans; D015994:Incidence; D008297:Male; D011471:Prostatic Neoplasms / Q000208:ethnology* / Q000235:genetics / Q000473:pathology*; D014481:United States / Q000453:epidemiology; D044465:White People