title: Paralysis in hedgehogs (Erinaceus europaeus) associated with demyelination.
abstract: Paraplegia affected 14 hedgehogs (Erinaceus europaeus) in a wildlife rescue hospital over a period of six months. Postmortem examination revealed demyelination in the brain and spinal cord and an inflammatory response in the meninges, choroid plexus and CNS. The peripheral nervous system was not affected. In the spleen, lungs and liver there was an accumulation of megakaryocytes and other evidence of extramedullary haemopoiesis, but there was no haematological evidence of anaemia. The pattern of disease incidence and the nature of the changes in the CNS suggest they were of viral origin, but no causal agent was isolated and the possibility of a neurotoxin cause cannot be ruled out.
authors.affiliation: Department of Clinical Veterinary Medicine, University of Cambridge.
authors.forename: A C
authors.initials: AC
authors.lastname: Palmer
authors.forename: W F
authors.initials: WF
authors.lastname: Blakemore
authors.forename: R J
authors.initials: RJ
authors.lastname: Franklin
authors.forename: L M
authors.initials: LM
authors.lastname: Frost
authors.forename: R E
authors.initials: RE
authors.lastname: Gough
authors.forename: J C
authors.initials: JC
authors.lastname: Lewis
authors.forename: D F
authors.initials: DF
authors.lastname: Macdougall
authors.forename: M T
authors.initials: MT
authors.lastname: O'Leary
authors.forename: L R
authors.initials: LR
authors.lastname: Stocker
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000473:pathology*; D003711:Demyelinating Diseases / Q000473:pathology / Q000662:veterinary*; D004196:Disease Outbreaks / Q000662:veterinary; D006364:Hedgehogs