Hydralazine-induced lupus and vocal fold paralysis.
Systemic lupus erythematosus (SLE) is a multi-system autoimmune disorder that can affect the upper airway. Hydralazine has been known to cause a lupus-like syndrome that can produce the clinical manifestations of SLE. We discuss a case of hydralazine-induced lupus, presenting with acute laryngeal oedema and right vocal fold paralysis. Cessation of hydralazine therapy resulted in reversal of paralysis.
Hari
C K
CK
Department of Otolaryngology and Head and Neck Surgery, Royal Gwent Hospital, Newport, U.K.
Raza
S A
SA
Clayton
M I
MI
D000959:Antihypertensive Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006830:Hydralazine / Q000009:adverse effects*; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D008875:Middle Aged; D014826:Vocal Cord Paralysis / Q000139:chemically induced*
D000959:Antihypertensive Agents; D006830:Hydralazine