title: How do some haemophiliacs develop inhibitors?
abstract: The purpose of this presentation is to concentrate on three issues: Is there an explanation for the large difference in reported incidence rates of inhibitor formation in haemophiliacs? Why do not all severe patients develop inhibitors? And how on the contrary do some patients with mild haemophilia develop inhibitors?
authors.affiliation: Centre for Molecular and Vascular Biology, University of Leuven, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: Vermylen
mesh_terms: D000906:Antibodies / Q000276:immunology*; D005169:Factor VIII / Q000235:genetics / Q000276:immunology* / Q000627:therapeutic use; D006467:Hemophilia A / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D009154:Mutation
chemical_list: D000906:Antibodies; D005169:Factor VIII