Exacerbation of systemic lupus erythematosus related to cytomegalovirus infection.
We report two patients with systemic lupus erythematosus (SLE) in whom cytomegalovirus (CMV) infection may have played a significant role in the exacerbation or onset of symptoms. The first patient had thrombocytopenia and the second had proteinuria. CMV infection was observed in both patients when their symptoms developed.
Hayashi
T
T
Department of Medicine, Jutendo University Izu-Nagaoka Hospital, Shizuoka, Japan.
Lee
S
S
Ogasawara
H
H
Sekigawa
I
I
Iida
N
N
Tomino
Y
Y
Hashimoto
H
H
Hirose
S
S
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D003587:Cytomegalovirus / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D004279:DNA, Viral / Q000302:isolation & purification; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000503:physiopathology*; D008775:Methylprednisolone / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D011507:Proteinuria; D013921:Thrombocytopenia
D000893:Anti-Inflammatory Agents; D000998:Antiviral Agents; D004279:DNA, Viral; D016756:Immunoglobulins, Intravenous; D011239:Prednisolone; D015774:Ganciclovir; D008775:Methylprednisolone