title: Quantitative analysis of acetaldehyde in whole blood from human and various animals by gas chromatography.
abstract: Acetaldehyde present in the blood of bull, chicken, hamster, horse, human, monkey, pig, rabbit, rat and sheep, was quantitatively analyzed by a newly developed gas chromatographic method. Acetaldehyde in a blood sample was reacted with cysteamine to give 2-methylthiazolidine, which was extracted with dichloromethane and subsequently analyzed by gas chromatography with a fused-silica capillary column and a nitrogen-phosphorus detector. The quantities of acetaldehyde found in blood ranged from 2.04 micromol/ml (hamster) to 14.8 micromol/ml (pig). The quantity of acetaldehyde recovered from human blood was 6.17 micromol/ml.
authors.affiliation: Department of Environmental Toxicology, University of California, Davis 95616, USA.
authors.forename: T
authors.initials: T
authors.lastname: Miyake
authors.forename: T
authors.initials: T
authors.lastname: Shibamoto
mesh_terms: D000079:Acetaldehyde / Q000097:blood*; D000328:Adult; D000818:Animals; D002849:Chromatography, Gas / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D013045:Species Specificity
chemical_list: D000079:Acetaldehyde