General synthesis of 3-substituted alkenyl GABA as potential anticonvulsants.
Stereospecific synthesis of cis and trans 3-substituted vinyl-gamma-aminobutyric acid analogs were obtained by either a Claisen rearrangement or a Wittig reaction from common diene precursors.
Serfass
L
L
Marion Merrell Dow, Strasbourg, France.
Casara
P J
PJ
D000927:Anticonvulsants / Q000138:chemical synthesis*; D008956:Models, Chemical; D013237:Stereoisomerism; D020888:Vigabatrin; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives* / Q000737:chemistry
D000927:Anticonvulsants; D005680:gamma-Aminobutyric Acid; D020888:Vigabatrin