Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures.
We evaluated the use of a new, controlled-release capsule form of carbamazepine, Carbatrol capsules, in an open-label, multicenter study of 124 patients with complex partial seizures. Ninety-one percent of the patients successfully completed the 6-month trial with good seizure control, with a significant improvement in quality of life. We conclude that switching patients with complex partial seizures from multiple daily-dose carbamazepine to twice-daily Carbatrol on a milligram-to-milligram basis is relatively safe.
Mirza
W U
WU
Department of Neurology, DePaul Hospital, Bridgeton, MO 63044, USA.
Rak
I W
IW
Thadani
V M
VM
Cereghino
J J
JJ
Garnett
W R
WR
Brown
L M
LM
Zhang
Y
Y
Belendiuk
G W
GW
D000293:Adolescent; D000328:Adult; D000368:Aged; D000927:Anticonvulsants / Q000008:administration & dosage*; D002220:Carbamazepine / Q000008:administration & dosage*; D003692:Delayed-Action Preparations; D017029:Epilepsy, Complex Partial / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D000927:Anticonvulsants; D003692:Delayed-Action Preparations; D002220:Carbamazepine