Endodermal sinus (yolk sac) tumor of oral cavity originating from gingiva.
Endodermal sinus tumor is a malignant germ cell tumor which usually arises in gonads. Extragonadal endodermal sinus tumors in the head and neck are very rare. Here a gingival endodermal sinus tumor is reported. The lesion demonstrated typical microscopic features of the endodermal sinus tumors of gonads. The tumor cells showed alpha-fetoprotein immunoreactivity in immunohistochemical evaluation. The serum alpha-fetoprotein level was high. This is the first gingival case in the related literature.
Kutluhan
A
A
Department of Otolaryngology, School of Medicine, Yüzüncü Yil University, Van, Turkey.
Uğraş
S
S
Akman
E
E
D001706:Biopsy; D018240:Endodermal Sinus Tumor / Q000097:blood / Q000276:immunology / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D005887:Gingival Neoplasms / Q000097:blood / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins