title: Successful combined lung and kidney transplantation for pulmonary lymphangioleiomyomatosis and renal angiolipomas.
abstract: Pulmonary lymphangioleiomyomatosis (LAM) and renal angiolipomas are rare but distinct clinical entities that share similar morphological features. Lung transplantation is considered as a valuable therapeutic modality in patients with end-stage pulmonary LAM. However, in some patients, renal complications due to bleeding angiomyolipomas and cyclosporin-induced nephropathy have become newly identified problems. This study reports the first case of combined lung and kidney transplantation for pulmonary lymphangioleiomyomatosis and renal angiolipomas. Two years after transplantation, renal and pulmonary function have remained stable and the patient has resumed a normal daily life, including a full-time professional activity.
authors.affiliation: Unit of Thoracic Surgery, University Hospital of Geneva, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: de Perrot
authors.forename: M
authors.initials: M
authors.lastname: Licker
authors.forename: J
authors.initials: J
authors.lastname: Robert
authors.forename: L
authors.initials: L
authors.lastname: Nicod
authors.forename: A
authors.initials: A
authors.lastname: Spiliopoulos
mesh_terms: D000328:Adult; D018206:Angiolipoma / Q000601:surgery*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D016030:Kidney Transplantation; D008175:Lung Neoplasms / Q000601:surgery*; D016040:Lung Transplantation; D018192:Lymphangioleiomyomatosis / Q000601:surgery*; D009378:Neoplasms, Multiple Primary / Q000601:surgery*