title: Combined experimental and Monte Carlo verification of 137Cs brachytherapy plans for vaginal applicators.
abstract: Dose rates in a phantom around a shielded and an unshielded vaginal applicator containing Selectron low-dose-rate 137Cs sources were determined by experiment and Monte Carlo simulation. Measurements were performed with thermoluminescent dosimeters in a white polystyrene phantom using an experimental protocol geared for precision. Calculations for the same set-up were done using a version of the EGS4 Monte Carlo code system modified for brachytherapy applications into which a new combinatorial geometry package developed by Bielajew was recently incorporated. Measured dose rates agree with Monte Carlo estimates to within 5% (1 SD) for the unshielded applicator, while highlighting some experimental uncertainties for the shielded applicator. Monte Carlo calculations were also done to determine a value for the effective transmission of the shield required for clinical treatment planning, and to estimate the dose rate in water at points in axial and sagittal planes transecting the shielded applicator. Comparison with dose rates generated by the planning system indicates that agreement is better than 5% (1 SD) at most positions. The precision thermoluminescent dosimetry protocol and modified Monte Carlo code are effective complementary tools for brachytherapy applicator dosimetry.
authors.affiliation: Department of Medical Physics, Cross Cancer Institute, Edmonton, Alberta, Canada.
authors.forename: R S
authors.initials: RS
authors.lastname: Sloboda
authors.forename: R
authors.initials: R
authors.lastname: Wang
mesh_terms: D000282:Administration, Intravaginal; D001918:Brachytherapy / Q000295:instrumentation; D002588:Cesium Radioisotopes / Q000008:administration & dosage*; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D008432:Mathematical Computing; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D014867:Water
chemical_list: D002588:Cesium Radioisotopes; D014867:Water