[Effective splenectomy in a patient with HIV-associated thrombocytopenia].
A 31-year-old man presented with a 3-month history of petechial hemorrhages. Physical examination revealed no splenomegaly. The patient's platelet count was 1.0 x 10(9)/l and bone marrow aspiration showed an elevated number of megakaryocytes. A diagnosis of HIV-associated thrombocytopenia was made on the basis of HIV seropositive results. The CD4 cell count was 400 x 10(6)/l. No opportunistic infections indicating AIDS were detected. Initially the patient was treated with predonisolone, but showed only a transient response. He also failed to respond to zidovudine, lamivudine, or indinavir. Following splenectomy, however, his platelet count rose above 80 x 10(9)/l (normal level: 150-350 x 10(9)/l).
Kato
Y
Y
Department of Internal Medicine, Tokyo Metropolitan Bokuto General Hospital.
Nakamura
K
K
Haraguchi
K
K
Ajima
A
A
Fujita
H
H
Tomiyama
J
J
Kudo
H
H
Onozawa
Y
Y
Ohnishi
K
K
Umekita
N
N
D000328:Adult; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D013156:Splenectomy; D013921:Thrombocytopenia / Q000601:surgery*