title: Relevance of the reduction of triglycerides in the prevention of coronary heart disease.
abstract: Triglyceride metabolism is complex and still poorly understood. Hypertriglyceridemia seems to enhance the risk for the development of coronary heart disease, but it cannot be regarded as a counterpart of hypercholesterolemia as a risk factor. The relevance of reduction of triglycerides in the prevention of coronary heart disease is still unclear. This is related to a number of problems, such as the lack of adequate clinical trials, heterogeneity in the abnormalities of triglyceride metabolism and unknown atherogenic threshold levels for serum triglycerides.
authors.affiliation: Department of Internal Medicine and Biocentre Oulu, University of Oulu, Finland.
authors.forename: Y A
authors.initials: YA
authors.lastname: Kesäniemi
mesh_terms: D002986:Clinical Trials as Topic; D003327:Coronary Disease / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D015228:Hypertriglyceridemia / Q000150:complications / Q000188:drug therapy*; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood*
chemical_list: D014280:Triglycerides