A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor.
Parker
M A
MA
Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907, USA.
Marona-Lewicka
D
D
Lucaites
V L
VL
Nelson
D L
DL
Nichols
D E
DE
D000818:Animals; D001572:Benzofurans / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D001667:Binding, Competitive; D004193:Discrimination Learning / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D008024:Ligands; D017397:Prefrontal Cortex / Q000187:drug effects / Q000378:metabolism; D011437:Propylamines / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D011869:Radioligand Assay; D051381:Rats; D044402:Receptor, Serotonin, 5-HT2A; D044403:Receptor, Serotonin, 5-HT2B; D044405:Receptor, Serotonin, 5-HT2C; D011985:Receptors, Serotonin / Q000187:drug effects* / Q000378:metabolism; D018490:Serotonin Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
C116535:4-(2-aminopropyl)-8-bromobenzofurano(6,5-a)furan; D001572:Benzofurans; D008024:Ligands; D011437:Propylamines; D044402:Receptor, Serotonin, 5-HT2A; D044403:Receptor, Serotonin, 5-HT2B; D044405:Receptor, Serotonin, 5-HT2C; D011985:Receptors, Serotonin; D018490:Serotonin Agents