title: [Homologous lamellar central limbokeratoplasty in severe limbal stem cell deficiency].
abstract: OBJECTIVE
  It is the purpose of this case report to present a new surgical technique for treatment of severe limbal stem cell deficiency.
  
  
  METHODS
  In a 42-year-old female patient with conjunctivalization of the cornea in congenital aniridia a homologous lamellar central limbokeratoplasty was performed. Postoperatively systemic Ciclosporin A was administered in order to prevent the transplanted limbal stem cells from immunological destruction. During the follow-up period of 16 months no immune reaction against the transplanted limbal stem cells could be observed. Visual acuity was ameliorated considerably.
  
  
  CONCLUSIONS
  Homologous lamellar central limbokeratoplasty is a promising surgical procedure in selected patients with severe limbal stem cell deficiency having less complications compared with penetrating central limbokeratoplasty.
authors.affiliation: Augenklinik der Heinrich-Heine-Universität, Düsseldorf.
authors.forename: R
authors.initials: R
authors.lastname: Sundmacher
authors.forename: T
authors.initials: T
authors.lastname: Reinhard
mesh_terms: D000328:Adult; D015783:Aniridia / Q000473:pathology* / Q000601:surgery*; D016039:Corneal Transplantation / Q000379:methods* / Q000473:pathology; D016572:Cyclosporine / Q000627:therapeutic use; D005260:Female; D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D016850:Limbus Corneae / Q000473:pathology*; D013234:Stem Cells / Q000473:pathology*; D014184:Transplantation, Homologous
chemical_list: D016572:Cyclosporine
vernacular_title: Homologe lamelläre zentrale Limbokeratoplasik bei schwerer Limbusstammzellinsuffizienz.