title: Effectiveness of kampo medicine (sai-boku-to) in treatment of patients with glossodynia.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the usefulness of a Kampo medicine (Sai-boku-to) for treatment of patients with glossodynia.
  
  
  METHODS
  Sai-boku-to or an antianxiety drug (diazepam) with vitamin B complex was administered orally for 3 months to each of 200 patients with glossodynia. Clinical examination evaluated the following subjective symptoms: pain, burning sensation, and discomfort. Effectiveness was evaluated as follows: "markedly effective," all 3 symptoms disappeared; "effective," pain improved; "ineffective," no improvement in pain.
  
  
  RESULTS
  The effective rates were 70% after 1 month, 85% after 2 months, and 92% after 3 months of administration of Sai-boku-to (the Kampo group) and 74% after 1 month, 71% after 2 months, and 69% after 3 months of administration of the antianxiety drug with vitamin B complex (the control group). No significant side effect was noted in the Kampo group, but sleepiness was recorded in 33 cases in the control group.
  
  
  CONCLUSIONS
  The results indicate that Sai-boku-to may be a clinically useful medicine for the long-term treatment of patients with glossodynia.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Bessho
authors.forename: Y
authors.initials: Y
authors.lastname: Okubo
authors.forename: S
authors.initials: S
authors.lastname: Hori
authors.forename: K
authors.initials: K
authors.lastname: Murakami
authors.forename: T
authors.initials: T
authors.lastname: Iizuka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D014151:Anti-Anxiety Agents / Q000627:therapeutic use; D016009:Chi-Square Distribution; D003975:Diazepam / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D005926:Glossalgia / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D014803:Vitamin B Complex / Q000627:therapeutic use
chemical_list: D014151:Anti-Anxiety Agents; D004365:Drugs, Chinese Herbal; D014803:Vitamin B Complex; D003975:Diazepam