title: ECT in the presence of intracranial aneurysm.
abstract: Two patients with known intracranial aneurysms (ICA) received electroconvulsive therapy (ECT). The first patient received ECT 4 years after the clipping of a right middle cerebral artery aneurysm. Treatment with esmolol failed to completely prevent an increase in blood pressure, but she did well nonetheless. The second patient underwent clipping of a basilar artery aneurysm 11 years before ECT. At the time of ECT, angiography showed a right paraophthalmic artery aneurysm. He received esmolol before each ECT, and, like the first patient, still had significant peri-ictal increases in his blood pressure, but otherwise tolerated the procedure well. Our experience and previously published literature indicate that even with pretreatment, patients often sustain significant increases in their blood pressure. However, this has not been accompanied by any morbidity. Possible guidelines for the management of ICA in association with ECT are discussed.
authors.affiliation: Department of Psychiatry, University of Rochester School of Medicine and Dentistry, New York, USA.
authors.forename: F
authors.initials: F
authors.lastname: Najjar
authors.forename: L B
authors.initials: LB
authors.lastname: Guttmacher
mesh_terms: D000318:Adrenergic beta-Agonists / Q000494:pharmacology / Q000627:therapeutic use; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D003866:Depressive Disorder / Q000628:therapy; D004565:Electroconvulsive Therapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D011412:Propanolamines / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000318:Adrenergic beta-Agonists; D011412:Propanolamines; C036604:esmolol