title: Bactericidal activity of catechin-copper (II) complexes on Escherichia coli ATCC11775 in the absence of hydrogen peroxide.
abstract: Washed Escherichia coli ATCC11775 cells were killed by (-)-epigallocatechin (EGC) in the presence of a non-lethal concentration of Cu2+ (1 mumol l-1) without additional H2O2, but not by (-)-epicatechin (EC). EGC alone (< 0.1 mmol l-1) did not reduce the viability of the cells. The survival curve obtained in the presence of EGC and Cu2+ was similar to that obtained in the presence of (-)-adrenaline (EN) and Cu2+.
authors.affiliation: Department of Chemistry, Shiga University of Medical Science, Japan. kimura@sums.shiga-med.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Kimura
authors.forename: N
authors.initials: N
authors.lastname: Hoshino
authors.forename: A
authors.initials: A
authors.lastname: Yamaji
authors.forename: F
authors.initials: F
authors.lastname: Hayakawa
authors.forename: T
authors.initials: T
authors.lastname: Ando
mesh_terms: D002392:Catechin / Q000494:pharmacology*; D003300:Copper / Q000494:pharmacology*; D004837:Epinephrine / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects*; D006861:Hydrogen Peroxide / Q000494:pharmacology
chemical_list: D003300:Copper; D002392:Catechin; D006861:Hydrogen Peroxide; D004837:Epinephrine