title: [Multi-organ involvement in recurrent Moschcowitz disease. Splenectomy as ultima ratio in a therapeutic dilemma?].
abstract: BACKGROUND
  The symptoms primarily described in Morbus Moschcowitz included thrombocytopenic purpura and hemolytic anemia. In addition it presents with a variety of clinical manifestations depending on the organs involved (i.e. neurological, renal, gastrointestinal, cardiac involvement). It is a rare disease and the pathogenesis still remains unclear. The efficacy of derived therapeutical concepts can hardly be assessed in controlled trials.
  
  
  CONCLUSIONS
  Currently the main option seems to be plasma therapy. In non-responders surgical procedures (splenectomy) may be of benefit to the patient.
authors.affiliation: Medizinische Klinik III, Klinikum Grosshadern der Ludwig-Maximilians-Universität München.
authors.forename: A R
authors.initials: AR
authors.lastname: Jakob
authors.forename: E
authors.initials: E
authors.lastname: Hiller
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D010951:Plasma Exchange; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis / Q000601:surgery*; D012008:Recurrence; D013156:Splenectomy; D016896:Treatment Outcome
vernacular_title: Multiorganbeteiligung bei rezidivierendem Morbus Moschcowitz. Splenektomie als Ultima ratio im therapeutischen Dilemma?