Analytical toxicology of fluorinated inhalation anaesthetics.
The chemical and pharmacological properties of the current fluorinated inhalation anaesthetics, halothane, enflurane, isoflurane, sevoflurane and desflurane, are surveyed with implications to toxicity. Analytical methods, especially gas chromatography with head space, purge and trap, or pulse heating extraction, are reviewed in forensic toxicological and occupational/therapeutic monitoring contexts.
Pihlainen
K
K
Department of Chemistry, University of Helsinki, Finland.
Ojanperä
I
I
D018685:Anesthetics, Inhalation / Q000009:adverse effects / Q000378:metabolism / Q000633:toxicity*; D000818:Animals; D002849:Chromatography, Gas; D005554:Forensic Medicine / Q000379:methods; D006801:Humans; D006845:Hydrocarbons, Fluorinated / Q000009:adverse effects / Q000378:metabolism / Q000633:toxicity*
D018685:Anesthetics, Inhalation; D006845:Hydrocarbons, Fluorinated