title: Relationships between an index of body fat distribution (based on waist and hip circumferences) and stature, and biochemical complications in obese children.
abstract: OBJECTIVE
  To determine the clinical utility of a new age-adjusted measure of body fat distribution (based on waist and hip circumferences) and stature, in relation to biochemical complications in obese children.
  
  
  METHODS
  Cross-sectional, clinical study. The formula to calculate the common standard deviation score (SDS) of waist-to-hip ratio/height (WHR/Ht) was obtained from the data of control children. The relationship between WHR/Ht SDS, as the age-adjusted measure, in obese children and their clinical laboratory data was evaluated.
  
  
  METHODS
  Outpatient obese Japanese children (102 boys and 75 girls) and control children (508 boys and 549 girls), ranging in age from 6-15 y.
  
  
  METHODS
  Height, body weight, waist girth, hip girth, triceps and subscapular skinfold thicknesses, as anthropometric measures. Percent overweight, percent body fat, waist girth, WHR and WHR/Ht SDS as criteria for obesity. Clinical laboratory analyses for fasting blood samples of obese children.
  
  
  RESULTS
  The WHR/Ht SDS closely correlated with age in obese children, thus reflecting the progress of abdominal obesity during growth. The obese boys were more hyperlipidaemic than the girls were, although the percent overweight was similar in both genders. The percent overweight, percent body fat, waist girth and WHR/Ht SDS all correlated well with triglyceride (TG), alanine aminotransferase (ALT) and insulin in boys, whereas only waist girth and WHR/Ht SDS showed a close correlation with TG and insulin in girls. The obese subjects were subdivided according to the number of abnormal values observed in TG, ALT and insulin. For obese boys, all five indices of obesity were higher in the groups with complications than in the group without. In the girls, only the WHR/Ht SDS constantly differed between subgroups. WHR/Ht SDS most obviously distinguished the groups with complications from the other group with a wide margin of difference (2-fold in boys and > 2-fold in girls) in the mean values.
  
  
  CONCLUSIONS
  The WHR/Ht SDS can serve as an index predicting the occurrence of biochemical complications in obese children ranging from the age of 6-15 y.
authors.affiliation: Department of Pediatrics, Yamanashi Medical University, Nakakomagun, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Asayama
authors.forename: K
authors.initials: K
authors.lastname: Hayashi
authors.forename: H
authors.initials: H
authors.lastname: Hayashibe
authors.forename: N
authors.initials: N
authors.lastname: Uchida
authors.forename: T
authors.initials: T
authors.lastname: Nakane
authors.forename: K
authors.initials: K
authors.lastname: Kodera
authors.forename: S
authors.initials: S
authors.lastname: Nakazawa
mesh_terms: D000273:Adipose Tissue; D000293:Adolescent; D000375:Aging; D000410:Alanine Transaminase / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D001823:Body Composition; D001824:Body Constitution; D001827:Body Height; D002648:Child; D005215:Fasting; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D009765:Obesity / Q000150:complications* / Q000503:physiopathology*; D012885:Skinfold Thickness; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D007328:Insulin; D014280:Triglycerides; D000410:Alanine Transaminase