Systemic mast cell disease associated with primary ovarian mixed malignant germ cell tumor.
A 12-year-old girl with a mixed malignant germ cell tumor of the ovary, treated by surgery and chemotherapy, developed systemic mast cell disease (SMCD) approximately 3 months after chemotherapy. Hematologic malignancies have previously been noted in patients with mediastinal germ cell tumors but this is the first report of a primary ovarian germ cell neoplasm associated with SMCD.
Teitell
M
M
Department of Pathology, Childrens Hospital Los Angeles and University of Southern California School of Medicine, 90027, USA.
Rowland
J M
JM
D002648:Child; D017809:Fatal Outcome; D005260:Female; D018237:Germinoma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008415:Mastocytosis / Q000150:complications* / Q000473:pathology; D018198:Mixed Tumor, Malignant / Q000150:complications* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology