title: Prosthesis-bone interface.
abstract: In this overview, which is based on selected books and reviews, the microscopic appearances of prosthesis-bone interfaces resulting from clinically relevant implantation techniques are highlighted. The following techniques are distinguished to insert and attach prostheses in the recipient bone: impaction into bone, primary mechanical interlocking, cement fixation, bone ongrowth and secondary mechanical interlocking with bioinert materials, and enhanced bone ongrowth and bone bonding to bioactive materials. The resulting typical histomorphologies of orthopedic and dental prostheses-bone interfaces are described and illustrated from the author's studies employing light, fluorescence, and backscattered electron microscopy, and corresponding microradiographs of undecalcified ground sections of bone and implants. Special emphasis is given to the mineralization-demineralization kinetics of the interfacial bone matrix interacting with specific surface reactions of some implant materials. Consequently, the distinction between bioinert and bioactive prosthetic materials is critically analyzed.
authors.affiliation: Department for Bone and Biomaterials Research, Histological-Embryological Institute, University of Vienna, Austria. Hanns.Plenk@univie.2c.2t
authors.forename: H
authors.initials: H
authors.lastname: Plenk
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001857:Bone Matrix / Q000502:physiology; D001842:Bone and Bones / Q000502:physiology*; D006801:Humans; D019736:Prostheses and Implants
chemical_list: D001672:Biocompatible Materials