title: [Experimental study and clinical application of arterialized venous skin flap].
abstract: In order to investigate the survival mechanism and the role of venous drainage in arterialized venous skin flap, 60 rabbits' ears were used for research and clinical application of the flap was performed subsequently in two cases. The rabbits were divided into 4 groups. Experimental group was standard arterialized venous skin flap, control 1 group was venous skin flap, control 2 group was arterialized venous skin flap with only one drainage vein and control 3 group was normal skin flap. The process of survival of the flaps was observed by hemodynamic and histological method. The results showed that there was no significant difference between standard arterialized venous skin flap and normal skin flap (P > 0.01). Two cases of arterialized venous skin flap survived completely. The conclusion were as follow: 1. the opening of collateral circulation between the veinlets was the main change of the microcirculation; 2. the blood flow of the graft was changed from unphysiological circulation to physiological circulation as the time elapsed and 3. amelioration of venous drainage was important in inproving the survival rate of arterialized vein graft.
authors.affiliation: Department of Plastic Surgery, Honey Lake Hospital of Shenzen, P.R. China.
authors.forename: J
authors.initials: J
authors.lastname: Chen
authors.forename: X
authors.initials: X
authors.lastname: Hao
authors.forename: S
authors.initials: S
authors.lastname: Luo
mesh_terms: D000328:Adult; D000818:Animals; D002921:Cicatrix / Q000601:surgery*; D003286:Contracture / Q000601:surgery; D004431:Ear, External / Q000098:blood supply / Q000601:surgery; D005260:Female; D006085:Graft Survival; D006227:Hand Deformities, Acquired / Q000601:surgery*; D006801:Humans; D008297:Male; D011817:Rabbits; D011897:Random Allocation; D012867:Skin / Q000098:blood supply*; D013524:Surgical Flaps; D014680:Veins / Q000637:transplantation