C. elegans neuroscience: genetics to genome.
From their earliest experiments, researchers using Caenorhabditis elegans have been interested in the role of genes in the development and function of the nervous system. As the C. elegans Genome Project completes the genomic sequence, we review the accomplishments of these researchers and the impact that the Genome Project has bad on their research. We also speculate on future directions in this research that are enabled by the efforts of the Genome Project.
Chalfie
M
M
Department of Biological Sciences, Columbia University, 1212 Amsterdam Avenue, New York, NY 10027, USA. mc21@columbia.edu
Jorgensen
E M
EM
D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics*; D016678:Genome; D008854:Microscopy, Electron