title: [A stimulus barrier model of early onset schizophrenia: an integrative etiological and therapeutic approach].
abstract: In the last few years neurobiological research has made a substantial contribution to an improved understanding of the neurodevelopmental origins of schizophrenia. Studies of functional and local brain-damage have illuminated the mechanisms of action of both the classical and the atypical neuroleptics and thus have considerable implications for a rational pharmacotherapy. Taking into account modern research on bonding, it is possible to elaborate a somato-psychosomatic model for the development of schizophrenia in childhood. The present review discusses the implications of this model for the treatment of children and adolescents with schizophrenia.
authors.affiliation: Rheinische Kliniken Essen, Klinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters.
authors.forename: C
authors.initials: C
authors.lastname: Eggers
mesh_terms: D000296:Adolescent Psychiatry / Q000379:methods; D017668:Age of Onset; D002665:Child Psychiatry / Q000379:methods; D006801:Humans; D008960:Models, Psychological; D012559:Schizophrenia / Q000628:therapy*