title: Left ventricular filling profiles and angiotensin system activity in elite baseball players.
abstract: Left ventricular (LV) filling profiles in elite baseball players has not been reported in the literature. Also, angiotensin system activity in athletes has never been reported. We used echocardiography to compare 20 male elite baseball players (aged 21.9+/-1.0 years) with those of age- and sex-matched healthy sedentary subjects. Compared with the normal group, the athlete group showed a significant increase in LV mass, LV diastolic and systolic dimension, and left atrial dimension (P<0.05, <0.001, <0.001, and <0.001, respectively). No differences in relative wall thickness or fractional shortening were found between these two groups. Diastolic filling profiles, including peak early diastolic filling velocity (E), peak late diastolic filling velocity (A), E:A ratio, early time-velocity integral (Ei), atrial time-velocity integral (Ai), Ei:Ai ratio, early filling time, deceleration time of early filling, and isovolumic relaxation time, were similar in both groups. Angiotensin system activity, including plasma renin activity, plasma aldosterone, and 24-h urinary aldosterone excretion, showed no difference between these two groups.
  
  
  CONCLUSIONS
  This study suggests that normal LV filling profile, which is mediated partly by normal angiotensin system activity, is not related to increase in LV dimension and mass in elite baseball players.
authors.affiliation: Department of Internal Medicine, Taipei Medical College Hospital 252, Taiwan.
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Lai
authors.forename: N C
authors.initials: NC
authors.lastname: Chang
authors.forename: M C
authors.initials: MC
authors.lastname: Tsai
authors.forename: C S
authors.initials: CS
authors.lastname: Lin
authors.forename: S H
authors.initials: SH
authors.lastname: Chang
authors.forename: T C
authors.initials: TC
authors.lastname: Wang
mesh_terms: D000328:Adult; D000450:Aldosterone / Q000097:blood / Q000652:urine; D001484:Baseball / Q000502:physiology*; D015992:Body Mass Index; D003971:Diastole; D004452:Echocardiography; D004562:Electrocardiography; D005080:Exercise Test; D006325:Heart Atria / Q000000981:diagnostic imaging; D006339:Heart Rate / Q000502:physiology; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D012083:Renin / Q000097:blood; D012084:Renin-Angiotensin System; D016277:Ventricular Function, Left
chemical_list: D000450:Aldosterone; D012083:Renin