title: A new high resolution radioimager for the quantitative analysis of radiolabelled molecules in tissue section.
abstract: We present a high-speed, high-resolution imager of beta particles. It is devoted to be used in autoradiography experiments such as receptor binding or in situ hybridization experiments, either instead of, or in complement with autoradiographic film and emulsions. It allows the user to locate and perform quantitative analyses of (3H, 14C, 35S, 33P, 32P, 125I) labelled molecules with a 15 microm spatial resolution on a 0.9 x 1.3 cm2 sensitive area. Combining recent techniques (specific scintillator thin sheets and intensified charge-coupled device (CCD)) this imager offers a wide dynamic range and real-time acquisition.
authors.affiliation: Institute de Physique Nucléaire, CNRS, Orsay, France.
authors.forename: P
authors.initials: P
authors.lastname: Laniece
authors.forename: Y
authors.initials: Y
authors.lastname: Charon
authors.forename: A
authors.initials: A
authors.lastname: Cardona
authors.forename: L
authors.initials: L
authors.lastname: Pinot
authors.forename: S
authors.initials: S
authors.lastname: Maitrejean
authors.forename: R
authors.initials: R
authors.lastname: Mastrippolito
authors.forename: B
authors.initials: B
authors.lastname: Sandkamp
authors.forename: L
authors.initials: L
authors.lastname: Valentin
mesh_terms: D000818:Animals; D001345:Autoradiography / Q000295:instrumentation / Q000379:methods*; D001610:Beta Particles; D017403:In Situ Hybridization / Q000379:methods; D007422:Intestines / Q000000981:diagnostic imaging; D007668:Kidney / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D051381:Rats; D014316:Tritium
chemical_list: D014316:Tritium