[A decrease in the level of erythrocytes with micronuclei under the influence of pyrimidine and thiazolidine derivatives in the blood of persons who came under radiation exposure as a result of the accident at the Siberian Chemical Combine].
The authors have found that pentoxylum (pyrimidine derivative) and leucogenum (thyazolidine derivative) are capable or reducing the number of cells with micronuclei in the blood of people who suffered from the radiation accident at the radiochemical works of the Siberian chemical plant. The most effective decrease in the cells with micronuclei in adults was observed two weeks after treatment, while in children the same result was achieved with leucogenum on the third day.
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D000328:Adult; D000398:Air Pollution, Radioactive / Q000009:adverse effects*; D002617:Chemical Industry; D002648:Child; D002869:Chromosome Aberrations; D004906:Erythrocyte Count / Q000187:drug effects / Q000528:radiation effects; D004912:Erythrocytes / Q000187:drug effects* / Q000528:radiation effects*; D006801:Humans; D048629:Micronuclei, Chromosome-Defective / Q000187:drug effects* / Q000528:radiation effects*; D015162:Micronucleus Tests; D010432:Pentoxyl / Q000008:administration & dosage*; D011837:Radiation-Protective Agents / Q000008:administration & dosage*; D018788:Radioactive Hazard Release; D011854:Radiochemistry; D012424:Rural Population; D012800:Siberia; D013607:Tablets; D013844:Thiazoles / Q000008:administration & dosage*; D053778:Thiazolidines
D011837:Radiation-Protective Agents; D013607:Tablets; D013844:Thiazoles; D053778:Thiazolidines; C001176:Leyk; D010432:Pentoxyl