title: Lower limb oedema following distal arterial bypass grafting.
abstract: Lower-limb oedema following arterial bypass surgery for ischemia is a common sequela which can complicate wound healing or delay resumption of mobility. Its exact pathogenesis remains uncertain but many theories have been proposed. Lymphatic disruption during arterial exposure, and endothelial damage from atrophy of the media and oxygen-derived free radical release are currently favoured hypotheses. Infrequently, deep vein thrombosis follows surgery and may exacerbate the condition. Efforts aimed at reducing the oedema, such as the use of lymphatic preserving incisional approaches or the use of antioxidants, have given conflicting results. The use of compression hosiery and leg elevation appear to be the most effective measures in reducing postoperative lower limb oedema.
authors.affiliation: Vascular Surgery Unit, Royal Victoria Hospital, Belfast, Northern Ireland, U.K.
authors.forename: C V
authors.initials: CV
authors.lastname: Soong
authors.forename: A A
authors.initials: AA
authors.lastname: Barros B'Sa
mesh_terms: D004487:Edema / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007511:Ischemia / Q000601:surgery*; D007866:Leg / Q000098:blood supply*; D014656:Vascular Surgical Procedures / Q000009:adverse effects*