Identification and characterization of the herpes simplex virus type 1 UL51 gene product.
The products of the herpes simplex virus type 1 UL51 gene were identified as phosphoproteins with apparent molecular masses of 27, 29 and 30 kDa. The proteins were produced at the late stage of infection, in a manner highly dependent on viral DNA synthesis, and were associated with extracellular virions. Immunofluorescence studies localized the UL51 proteins mainly to the cytoplasm, both in infected Vero cells and in transfected COS-1 cells singly expressing the UL51 gene.
Daikoku
T
T
Laboratory of Virology, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Japan.
Ikenoya
K
K
Yamada
H
H
Goshima
F
F
Nishiyama
Y
Y
D000818:Animals; D019556:COS Cells; D002522:Chlorocebus aethiops; D018259:Herpesvirus 1, Human / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D010750:Phosphoproteins / Q000235:genetics* / Q000378:metabolism*; D011817:Rabbits; D014709:Vero Cells; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism*
D010750:Phosphoproteins; C116751:UL51 protein, HSV-1; D014764:Viral Proteins