Characterization of calcified deposits on contraceptive intrauterine devices.
The formation of calcified deposits on > 200 contraceptive intrauterine devices (IUD) was quantitated as a function of time in healthy women, pregnant women, and women with a pathologic lesion. The incrustment formation was significantly enhanced when inflammation occurred, but change could not be observed in cases of pregnancy. The incrustments were analyzed by x-ray diffraction, infrared spectroscopy, x-ray microprobe, and ultramicrochemical stone analysis techniques. Major components and their average w/w percent quantities in the incrustments are as follows: calcium carbonate 75%, apatite 5%, and organic matrix 20%. Earlier hypotheses on the chemical processes of deposit formation are discussed, and a new, ionic mechanism of calcification on IUD surfaces is suggested.
Patai
K
K
Second Department of Obstetrics and Gynecology, Medical School, Semmelweis University, Budapest, Hungary.
Berényi
M
M
Sipos
M
M
Noszál
B
B
D002114:Calcinosis / Q000209:etiology*; D002119:Calcium Carbonate / Q000032:analysis; D017886:Durapatite / Q000032:analysis; D005260:Female; D006801:Humans; D007249:Inflammation / Q000209:etiology; D007434:Intrauterine Devices / Q000009:adverse effects*; D013997:Time Factors
D017886:Durapatite; D002119:Calcium Carbonate