Candida catenulata fungemia in a cancer patient.
We report the first case of fungemia due to Candida catenulata, a contaminant of dairy products. C. catenulata was isolated from three blood cultures of a patient with gastric cancer. The patient failed to respond to fluconazole but recovered after treatment was switched to amphotericin B. In vitro, C. catenulata was susceptible to amphotericin B and itraconazole and was also susceptible to fluconazole in dose-dependent manner. The likely portal of entry was the digestive tract, as the patient often ate cheese and had multiple gastric ulcerations.
Radosavljevic
M
M
Institut de Parasitologie et de Pathologie Tropicale, Faculté de Médecine, 67000 Strasbourg, France.
Koenig
H
H
Letscher-Bru
V
V
Waller
J
J
Maloisel
F
F
Lioure
B
B
Herbrecht
R
R
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001769:Blood / Q000382:microbiology; D002175:Candida / Q000302:isolation & purification*; D002177:Candidiasis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D016469:Fungemia / Q000382:microbiology*; D006801:Humans; D013274:Stomach Neoplasms / Q000150:complications*
D000935:Antifungal Agents; D000666:Amphotericin B