A further report on a case of Floating-Harbor Syndrome in a mother and daughter.
We present the most extensive neuropsychological and language assessment yet reported of patients diagnosed with Floating-Harbor Syndrome (FHS), a rare genetic condition characterized by dysmorphid figures, short stature, and speech-onset delay. This is also the second reported occurrence of both a mother and daughter with FHS. Whereas the child demonstrated gross deficits in verbal expression, speech and language problems were largely ameliorated in the mother. Neuropsychological assessment also revealed a strikingly similar pattern of cognitive problems additional to language dysfunction, including difficulties with attention, mathematical, and visuospatial abilities. A mood disorder continued to be quite disabling for the mother.
Rosen
A C
AC
Medical College of Wisconsin, Milwaukee, USA. AllysonvRosen@nih.gov
Newby
R F
RF
Sauer
C M
CM
Lacey
T
T
Hammeke
T A
TA
Lubinsky
M S
MS
D000328:Adult; D000339:Affect / Q000502:physiology; D001288:Attention / Q000502:physiology; D003071:Cognition / Q000502:physiology; D005145:Face / Q000002:abnormalities*; D005260:Female; D006130:Growth Disorders / Q000523:psychology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007805:Language Development Disorders / Q000523:psychology*; D007807:Language Tests; D009483:Neuropsychological Tests; D010465:Perception / Q000502:physiology; D010551:Personality / Q000502:physiology; D011247:Pregnancy; D011597:Psychomotor Performance / Q000502:physiology; D013060:Speech; D013577:Syndrome