title: Epidemiology of clonorchiasis in Ninh Binh Province, Vietnam.
abstract: Clinical and stool examinations for clonorchiasis were carried out in an endemic area, Kim Son District, Ninh Binh Province, Vietnam. Stool examination with the Kato-Katz technic revealed that in 306 residents selected randomly, 42 people (13.7%) were infected with Clonorchis sinensis. The rate was biased towards men (23.4%) as opposed to women (1.5%) and increased with age. No children younger than 10 years old were infected, reflecting difference in a chance for acquisition of infection through a habit of eating raw fish. Few clinical abnormalities were found by blood and urine examinations of the patients. Treatment with praziquantel decreased the infection rate to 5.3% at 6 weeks later. Snails, Melanoides tuberculatus, collected from ponds around the settlements were infected with cercariae at a rate of 13.3%. Farmed fish (Hypophthalmichtys molitrix) in the ponds were infected with metacercariae at rates of 56.4% in small individuals and 100% in large ones. The life cycle of C. sinensis is exclusively completed in the ponds and the traditional habit of eating raw fish in summer was thought to be a major route of infection.
authors.affiliation: Department of Parasitology, Hamamatsu University School of Medicine, Japan. kino624@hama-med.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Kino
authors.forename: H
authors.initials: H
authors.lastname: Inaba
authors.forename: N
authors.initials: N
authors.lastname: Van De
authors.forename: L
authors.initials: L
authors.lastname: Van Chau
authors.forename: D T
authors.initials: DT
authors.lastname: Son
authors.forename: H T
authors.initials: HT
authors.lastname: Hao
authors.forename: N D
authors.initials: ND
authors.lastname: Toan
authors.forename: L D
authors.initials: LD
authors.lastname: Cong
authors.forename: M
authors.initials: M
authors.lastname: Sano
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000818:Animals; D000980:Antiplatyhelmintic Agents / Q000627:therapeutic use; D002648:Child; D003003:Clonorchiasis / Q000188:drug therapy / Q000453:epidemiology* / Q000635:transmission; D003004:Clonorchis sinensis / Q000302:isolation & purification*; D004032:Diet; D005243:Feces / Q000469:parasitology; D005260:Female; D005399:Fishes / Q000469:parasitology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use; D012737:Sex Factors; D012908:Snails / Q000469:parasitology; D014744:Vietnam / Q000453:epidemiology
chemical_list: D000980:Antiplatyhelmintic Agents; D011223:Praziquantel