title: Single-fiber electromyography of the laryngeal muscles.
abstract: Single-fiber electromyography (SFEMG) is useful in the evaluation of disorders of neuromuscular transmission and the assessment of motor unit morphology. Standard EMG techniques are used routinely in the evaluation of laryngeal dysfunction, but the feasibility of laryngeal SFEMG has not been established. We, therefore, performed laryngeal SFEMG in 10 normal individuals to demonstrate the feasibility of the technique and generate preliminary normative data. We also studied 2 patients with amyotrophic lateral sclerosis and 1 patient previously treated with botulinum toxin for comparative purposes.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, CHUV (University Hospital of Lausanne), Switzerland.
authors.forename: V
authors.initials: V
authors.lastname: Schweizer
authors.forename: G E
authors.initials: GE
authors.lastname: Woodson
authors.forename: T E
authors.initials: TE
authors.lastname: Bertorini
mesh_terms: D000328:Adult; D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000473:pathology / Q000503:physiopathology; D001905:Botulinum Toxins / Q000627:therapeutic use; D004576:Electromyography / Q000379:methods*; D005260:Female; D006801:Humans; D007821:Laryngeal Muscles / Q000473:pathology / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D018485:Muscle Fibers, Skeletal / Q000473:pathology / Q000502:physiology; D009128:Muscle Spasticity / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D013064:Speech Disorders / Q000473:pathology / Q000503:physiopathology; D009435:Synaptic Transmission
chemical_list: D001905:Botulinum Toxins