[A case of malignant rheumatoid arthritis complicated by secondary amyloidosis and membranous nephropathy].
A 30-year-old man had been treated for malignant rheumatoid arthritis from 1989 with a non-steroidal anti-inflammatory drug, then bucillamine for six months and prednisolone. Mild proteinuria appeared in May 1994, 4 years after bucillamine therapy was conducted. The patient was admitted to our hospital for a renal biopsy in July 1994. The specimen revealed secondary amyloidosis and membranous nephropathy (MGN). These findings suggest that MGN unrelated to bucillamine therapy might have occurred with secondary amyloidosis in rheumatoid arthritis.
Nakanishi
K
K
Second Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan.
Iwahashi
C
C
Handa
Y
Y
Hara
N
N
Hamada
K
K
Nagai
Y
Y
Kawamura
S
S
Nakamura
K
K
D000328:Adult; D000686:Amyloidosis / Q000209:etiology*; D001172:Arthritis, Rheumatoid / Q000150:complications*; D015433:Glomerulonephritis, Membranous / Q000209:etiology* / Q000473:pathology; D006509:Hepatitis B / Q000150:complications; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D011507:Proteinuria / Q000209:etiology