title: [The regulation of experiments on animals--ethics, legislation and alternatives].
abstract: Legislation and rules for animal experiments in many countries are proposed. Activities of international and national organizations, committees and administrative authorities are described. The importance of the three Rs principle and alternative methods for the humanization of bio-medical animal experiments are discussed.
authors.affiliation: Scientific Research Laboratory of Experimental-Biological Models, Russian Academy of Medical Sciences, Moscow Region.
authors.forename: R A
authors.initials: RA
authors.lastname: Kopaladze
mesh_terms: D000826:Animal Testing Alternatives / Q000331:legislation & jurisprudence / Q000592:standards*; D000818:Animals; D000830:Animals, Laboratory; D001315:Australia; D002170:Canada; D004989:Ethics; D005060:Europe; D007564:Japan; D009520:New Zealand; D012106:Research / Q000331:legislation & jurisprudence / Q000592:standards*; D014481:United States