Laparoscopy in 533 patients with abdominal malignancy.
BACKGROUND
Laparoscopy in patients with intra-abdominal malignancy remains controversial. This study evaluates the incidence of tumor recurrence at the port site after laparoscopy in patients with intra-abdominal malignancy.


METHODS
The medical records of all patients with nongynecologic malignancies who underwent laparoscopic procedures between May 1, 1990, and June 30, 1996, at the University of Texas M.D. Anderson Cancer Center were reviewed. Data on extent of tumor, histologic findings, primary location, procedures performed, and complications were recorded.


RESULTS
During this time, 533 patients with known intra-abdominal malignancies underwent laparoscopy. Mean follow-up time was 13.2 +/- 0.5 months (range 1 to 71 months; median 10.6 months). Four recurrences at the port site were identified (0.8%). Three of these patients had advanced intra-abdominal disease at the time of laparoscopy; 1 patient without advanced disease at the time of laparoscopy had a recurrence at the port site as the only site of recurrent disease (0.19%). The incidence of port site recurrences among patients with advanced intra-abdominal disease at the time of laparoscopy (3/71) was significantly greater than the risk of development of a recurrence at the port site among patients without advanced intra-abdominal disease at the time of laparoscopy (1/462; P < .0003, by chi-square analysis).


CONCLUSIONS
Recurrence at the port site is very rare. When implantation at the port site does occur, it is most commonly associated with advanced intra-abdominal disease.
Pearlstone
D B
DB
University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
Mansfield
P F
PF
Curley
S A
SA
Kumparatana
M
M
Cook
P
P
Feig
B W
BW
D000008:Abdominal Neoplasms / Q000145:classification / Q000601:surgery*; D000230:Adenocarcinoma / Q000601:surgery; D000328:Adult; D003110:Colonic Neoplasms / Q000601:surgery; D019992:Databases as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D010535:Laparoscopy / Q000009:adverse effects; D008223:Lymphoma / Q000601:surgery; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology*; D010190:Pancreatic Neoplasms / Q000601:surgery; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000601:surgery; D013997:Time Factors