title: [The 13C-urea breath test in Helicobacter pylori gastric infection in children].
abstract: Helicobacter pylori gastric infection in children is a public health problem. Classical diagnostic tools such as endoscopy are excessively invasive in the usual clinical context. Serology at this age has multiple drawbacks. The urea-13C breath test seems today the most appropriate alternative method. The principle of the test relies upon the indirect detection of H pylori through its high urease activity. The test uses a stable (ie, non radioactive) isotope, which allows its repeated use. The main indications are the detection and the follow-up of H pylori infection.
authors.affiliation: Unité de gastroentérologie, hôpital Saint-Vincent-de-Paul, Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Kalach
authors.forename: P H
authors.initials: PH
authors.lastname: Benhamou
authors.forename: F
authors.initials: F
authors.lastname: Briet
authors.forename: J
authors.initials: J
authors.lastname: Raymond
authors.forename: C
authors.initials: C
authors.lastname: Dupont
mesh_terms: D000328:Adult; D000367:Age Factors; D001944:Breath Tests / Q000379:methods*; D002247:Carbon Isotopes; D002648:Child; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000201:enzymology; D006801:Humans; D008297:Male; D013058:Mass Spectrometry; D011247:Pregnancy; D014508:Urea; D014510:Urease / Q000032:analysis
chemical_list: D002247:Carbon Isotopes; D014508:Urea; D014510:Urease