Retrospective analysis of the Beijing family of Mycobacterium tuberculosis in preserved lung tissues.
Direct repeat spoligotyping of 85 paraffin-embedded lung biopsies was used to investigated the occurrence around Beijing of the Beijing family of Mycobacterium tuberculosis. Samples ranged in time from 1956 to 1990. Hybridization patterns were found with 49 (58%) samples, and 45 (92%) produced typical Beijing family patterns extending over the 34-year period.
Qian
L
L
Department of Microbiology, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA.
Van Embden
J D
JD
Van Der Zanden
A G
AG
Weltevreden
E F
EF
Duanmu
H
H
Douglas
J T
JT
D015373:Bacterial Typing Techniques; D001706:Biopsy; D002681:China; D006801:Humans; D008168:Lung / Q000382:microbiology*; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000302:isolation & purification*; D009693:Nucleic Acid Hybridization; D009838:Oligodeoxyribonucleotides / Q000032:analysis; D016612:Paraffin Embedding; D016133:Polymerase Chain Reaction / Q000379:methods; D012189:Retrospective Studies; D014376:Tuberculosis / Q000382:microbiology*
D009838:Oligodeoxyribonucleotides