title: Catastrophic hypoadrenalism in a case of Sjögren's syndrome.
abstract: We describe a patient with Sjögren's syndrome who died from undiagnosed adrenocortical failure. A positive test for adrenocortical antibody, performed pre-terminally, suggested the underlying diagnosis, which was subsequently confirmed at post-mortem. This case highlights the rare association of Sjögren's syndrome with occult adrenocortical failure. Perhaps a greater awareness of this association and more frequent serological screening are necessary to prevent a fatal outcome.
authors.affiliation: Department of Rheumatology, Warrington Hospital NHS Trust, Cheshire, UK.
authors.forename: K
authors.initials: K
authors.lastname: Chakravarty
authors.forename: D
authors.initials: D
authors.lastname: Sarma
authors.forename: M S
authors.initials: MS
authors.lastname: al-Jafari
mesh_terms: D000309:Adrenal Insufficiency / Q000150:complications*; D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D012859:Sjogren's Syndrome / Q000150:complications*