title: L-cone pigment genes expressed in normal colour vision.
abstract: To directly test the hypothesis that only two pigment genes are expressed from the X-chromosome array, we examined expressed M and L pigment gene sequences from > 100 male eye donors. In this sample, there were eight men who expressed high levels of more than one L pigment gene in addition to M pigment genes. The fact that these eyes expressed both L and M pigment genes at significant levels suggests they were from men with normal colour vision. We reject the hypothesis that only two pigment genes from one X-chromosome array can be expressed.
authors.affiliation: Department of Cellular Biology and Anatomy, Medical College of Wisconsin, Milwaukee 53226-0509, USA.
authors.forename: S A
authors.initials: SA
authors.lastname: Sjoberg
authors.forename: M
authors.initials: M
authors.lastname: Neitz
authors.forename: S D
authors.initials: SD
authors.lastname: Balding
authors.forename: J
authors.initials: J
authors.lastname: Neitz
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D002874:Chromosome Mapping; D003118:Color Perception / Q000502:physiology*; D018076:DNA, Complementary / Q000032:analysis; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D017949:Retinal Cone Photoreceptor Cells / Q000502:physiology*; D012168:Retinal Pigments / Q000235:genetics*; D014960:X Chromosome
chemical_list: D018076:DNA, Complementary; D012168:Retinal Pigments