Segregating sites in a gene conversion model with mutation.
Formulae for the expectation and variance of the number of segregating and homogeneous sites in a sample of two chromosomes are found. The model includes gene conversion and infinitely-many-alleles mutation in a coalescent framework. The corresponding infinitely-many-sites model limits are also found. The formulae for the expectation are extended to any sample size. Comparisons are drawn between the pure mutation model and the model where gene conversion has been added.
Bahlo
M
M
Department of Mathematics and Statistics, Monash University, Clayton, Victoria, 3168, Australia.
D020090:Chromosome Segregation / Q000235:genetics*; D005785:Gene Conversion / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics; D008390:Markov Chains; D008957:Models, Genetic; D005810:Multigene Family / Q000235:genetics*; D009154:Mutation / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics; D015203:Reproducibility of Results; D012639:Seeds / Q000235:genetics