Elevated blood lead levels in children are associated with lower erythropoietin concentrations.
Eighty-six children (mean age, 34 months) were studied to determine whether elevated blood lead levels in children are associated with lower erythropoietin concentrations. The median erythropoietin concentration was 5.9 mIU/mL (range, 2.3 to 11.5 mIU/mL), and the median blood lead level was 0.87 micromol/L (18 microg/dL; range, 2 to 84 microg/dL). Blood lead concentration was inversely and independently related to erythropoietin concentration.
Liebelt
E L
EL
Department of Pediatrics and The Children's Clinical Research Center, Yale University School of Medicine; New Haven, Connecticut, USA.
Schonfeld
D J
DJ
Gallagher
P
P
D000704:Analysis of Variance; D002648:Child; D002675:Child, Preschool; D004791:Enzyme Inhibitors / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D004921:Erythropoietin / Q000097:blood*; D005260:Female; D006801:Humans; D007223:Infant; D007854:Lead / Q000097:blood*; D008297:Male; D010865:Pilot Projects; D011524:Protoporphyrins / Q000097:blood
D004791:Enzyme Inhibitors; D011524:Protoporphyrins; D004921:Erythropoietin; C017803:zinc protoporphyrin; D007854:Lead