title: Brachytherapy and vaginal hysterectomy for low-stage uterine cervix carcinoma.
abstract: OBJECTIVE
  The aim of this study was to assess safety and efficiency of a limited vaginal hysterectomy after brachytherapy in patients with early uterine cervix carcinoma without unfavorable prognostic factors. All tumors were less than 1.5 cm in diameter.
  
  
  METHODS
  Between October 1992 and December 1995, 22 patients with low-stage uterine cervix carcinoma (stage Ia2 with vascular invasion, 3 cases; stage Ib1, 19 cases) were included in this study. Patients underwent the following procedures: single utero-vaginal brachytherapy after a previous negative laparoscopic lymphadenectomy (median number of lymph nodes: 12) followed 6 weeks later by a limited vaginal hysterectomy.
  
  
  RESULTS
  Two mild intraoperative complications were noted. Venous hemorrhage (100 cc) occurred in one patient during lymphadenectomy and another patient experienced bladder injury during hysterectomy. These two complications were successfuly controlled with no need for laparotomy. Only one late complication was observed and was evaluated as a bladder grade G2(b) according to the Franco-Italian glossary. With a 30 (22-50) month follow-up, no recurrence was reported.
  
  
  CONCLUSIONS
  These results appear promising in patients with very early cervix carcinoma but remain to be confirmed on a larger scale.
authors.affiliation: Department of Obstetrics & Gynecology B, La Conception Hospital, 147 Bvd. Baille, Marseille Cedex 5, 13385, France.
authors.forename: L
authors.initials: L
authors.lastname: Cravello
authors.forename: L
authors.initials: L
authors.lastname: Gonzague-Casabianca
authors.forename: V
authors.initials: V
authors.lastname: Roger
authors.forename: C
authors.initials: C
authors.lastname: d'Ercole
authors.forename: C
authors.initials: C
authors.lastname: Smart
authors.forename: B
authors.initials: B
authors.lastname: Blanc
authors.forename: M
authors.initials: M
authors.lastname: Resbeut
mesh_terms: D000328:Adult; D001918:Brachytherapy / Q000009:adverse effects; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000009:adverse effects; D008875:Middle Aged; D009367:Neoplasm Staging; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*