Primary cerebral malignant melanoma: an unusual cause of dyspraxia.
Primary intracranial melanomas are rare and occur mainly in young adults. Originating from leptomeningeal melanoblasts and extending into the parenchyma, the tumours closely resemble meningiomas, from which they are radiologically difficult to distinguish despite progress in neuroimaging. Definitive diagnosis is usually made on histopathological examination, though confirmed only after post-mortem examination in some cases. Prolonged disease-free periods, and in rare cases long-term survival, are possible following successful total surgical excision. This case presented with typical clinical features but, at 79 years old, an unusual age.
Farnsworth
T A
TA
Department of Medicine for the Elderly, Castle Hill Hospital, Cottingham, E. Yorks, UK.
D000368:Aged; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000150:complications / Q000473:pathology*