title: Automatic motion correction in dynamic radionuclide renography using image registration.
abstract: Time-activity curves from dynamic renograms can be analysed to yield important quantitative parameters. However, accurate results are dependent on curves being free from artefacts caused by patient movement. We describe a method to correct for both translational and rotational motion during renography. The method is image-based and does not require markers. Sequential dynamic frames are registered using an affine transform from which rotational and translational components are extracted by singular-value decomposition. Computer simulations demonstrate correction to < 1 pixel and < 1 degree. The method is also fast, with renograms comprising 75 frames of 64 x 64 pixels taking under 1 min for correction on a Sun SPARC 5.
authors.affiliation: Department of Medical Physics, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: K J
authors.initials: KJ
authors.lastname: Lee
authors.forename: D C
authors.initials: DC
authors.lastname: Barber
mesh_terms: D001331:Automation; D003198:Computer Simulation; D003205:Computing Methodologies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007668:Kidney / Q000000981:diagnostic imaging*; D009068:Movement; D011866:Radioisotope Renography / Q000379:methods*