title: Utility of PCR assay in diagnosis of en-plaque tuberculoma of the brain.
abstract: This is the first report of a case in which diagnosis of en-plaque tuberculoma on the basis of magnetic resonance imaging (MRI) findings was confirmed by a Mycobacterium tuberculosis complex-specific PCR assay of cerebrospinal fluid. The accuracy of the diagnosis was supported by good response to antitubercular drugs, which was shown by repeat MRI studies performed after treatment.
authors.affiliation: Department of Biotechnology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: K K
authors.initials: KK
authors.lastname: Singh
authors.forename: M D
authors.initials: MD
authors.lastname: Nair
authors.forename: K
authors.initials: K
authors.lastname: Radhakrishnan
authors.forename: J S
authors.initials: JS
authors.lastname: Tyagi
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D001921:Brain / Q000473:pathology; D002555:Cerebrospinal Fluid / Q000382:microbiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D012680:Sensitivity and Specificity; D016862:Tuberculoma, Intracranial / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents