Chromatin modification: how to put a HAT on the histones.
Specific patterns of acetylation of the core histones are associated with specific structures and functions of chromatin. A basis for the specificity of acetylation is now apparent in the recent crystal structures of two acetyltransferases.
Travers
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MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK.
D000107:Acetylation; D000123:Acetyltransferases / Q000737:chemistry / Q000378:metabolism*; D002843:Chromatin / Q000201:enzymology / Q000502:physiology*; D004789:Enzyme Activation; D051548:Histone Acetyltransferases; D006657:Histones / Q000737:chemistry / Q000378:metabolism*; D013379:Substrate Specificity
D002843:Chromatin; D006657:Histones; D000123:Acetyltransferases; D051548:Histone Acetyltransferases; C110880:histone acetyltransferase type B complex