Simplifying the molecular mechanisms of human papillomavirus.
Human papillomaviruses are a common human pathogen responsible for diseases varying in severity from warts to cervical cancer. This article examines the functions of the viral gene products and how they interact with cellular factors to replicate themselves and cause disease.
Saunders
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Epithelial Pathobiology Group, University of Queensland Department of Medicine, Princess Alexandra Hospital, Brisbane, Australia. NSaunders@medicine.pa.uq.edu.au
Frazer
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IH
D000956:Antigens, Viral / Q000235:genetics; D002213:Capsid / Q000235:genetics; D002472:Cell Transformation, Viral / Q000235:genetics; D003218:Condylomata Acuminata / Q000821:virology; D004268:DNA-Binding Proteins / Q000235:genetics; D005260:Female; D016147:Genes, Tumor Suppressor / Q000235:genetics; D005814:Genes, Viral / Q000235:genetics; D006801:Humans; D015603:Keratinocytes / Q000166:cytology / Q000378:metabolism; D008967:Molecular Biology; D009687:Nuclear Proteins / Q000235:genetics; D009856:Oncogene Proteins, Viral / Q000235:genetics; D027383:Papillomaviridae / Q000145:classification / Q000235:genetics* / Q000502:physiology; D030361:Papillomavirus Infections / Q000503:physiopathology; D014158:Transcription, Genetic; D014412:Tumor Virus Infections / Q000503:physiopathology; D002583:Uterine Cervical Neoplasms / Q000821:virology; D014764:Viral Proteins / Q000235:genetics; D014779:Virus Replication / Q000235:genetics
D000956:Antigens, Viral; D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; D009856:Oncogene Proteins, Viral; D014764:Viral Proteins