Pulmonary disease in the immunocompromised child.
Immune deficiency states in children may be related to primary immunodeficiency syndromes or secondary disorders of the immune system. The secondary immunodeficiencies in children include human immunodeficiency virus-associated acquired immunodeficiency, as well as immunosuppression secondary to antineoplastic chemotherapeutic agents, bone marrow transplantation, and drugs given to prevent transplant rejection. This article discusses the common primary and secondary immunocompromised states of childhood, with emphasis on their attendant infectious, lymphoproliferative, and neoplastic complications.
Pennington
D J
DJ
Department of Radiology, Indiana University Medical Center, Indianapolis 46202-5200, USA.
Lonergan
G J
GJ
Benya
E C
EC
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis; D000293:Adolescent; D000970:Antineoplastic Agents / Q000009:adverse effects; D016026:Bone Marrow Transplantation / Q000009:adverse effects / Q000276:immunology; D002648:Child; D006801:Humans; D007108:Immune Tolerance; D016867:Immunocompromised Host; D007153:Immunologic Deficiency Syndromes / Q000150:complications; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008171:Lung Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology; D008175:Lung Neoplasms / Q000150:complications; D008232:Lymphoproliferative Disorders / Q000209:etiology
D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents