[HHV-8 related diseases].
KAPOSI'S DISEASE: HHV-8 sequences have been found in all the epidemiological forms of Kaposi's disease. There is a direct relationship between HHV-8 infection and PBMC and later development of Kaposi's disease. The HHV-8 sequences can be found in spindle cells or endothelial cells in Kaposi lesions. OTHER DISEASES: HHV-8 is also associated with certain lymphomas including body-cavity-based lymphomas and Castleman's disease. It has also been put forward that there is a relationship between HHV-8 and multiple myeloma, epithelial tumors in kidney transplant recipients, angiosarcoma, and angiolymphoid hyperplasia.
Calvez
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V
Dpt de Virologie CERVI, Hôpital de la Pitié-Salpêtrière, Paris.
Bossi
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P
D019288:Herpesvirus 8, Human; D006801:Humans; D012514:Sarcoma, Kaposi / Q000821:virology*; D014983:Xeroderma Pigmentosum / Q000821:virology*