title: Stabilization and accurate trimming of nerve ends: practical use of fibrin glue: technical note.
abstract: OBJECTIVE
  Peripheral nerve transection usually results in protrusion of the endoneurial contents ("mushrooming"). Trimming of the nerve ends before repair is often necessary to achieve cut nerve end planes. In this technical report, we describe a technique for stabilization and accurate trimming of nerve ends using fibrin glue.
  
  
  METHODS
  The nerve ends of divided peripheral nerves are coated with fibrin glue and subsequently trimmed using a razor blade before repair.
  
  
  RESULTS
  When fibrin glue is applied, a firm layer with a rubbery consistency is formed around the nerve. This layer stabilizes the nerve ends during trimming, and a clear-cut plane of the nerve can be achieved. Moreover, the fibrin glue stabilizes the nerve ends during manipulations caused by suturing of the nerve.
  
  
  CONCLUSIONS
  The technique results in easier handling of the nerve during trimming and manipulation, minimal tissue damage to the nerve, and a clear-cut plane of the nerve.
authors.affiliation: Department of Neurosurgery, University Hospital Nijmegen St. Radboud, The Netherlands.
authors.forename: T
authors.initials: T
authors.lastname: Menovsky
authors.forename: R H
authors.initials: RH
authors.lastname: Bartels
mesh_terms: D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D006801:Humans; D008866:Microsurgery; D010525:Peripheral Nerves / Q000473:pathology / Q000601:surgery*; D013536:Suture Techniques
chemical_list: D015718:Fibrin Tissue Adhesive