[Effects of low radiation doses on Chinese hamster cells].
The induction of cytogenetic damages after irradiation with single dose of gamma-rays (0.1-2 Gy) have been studied. It is shown non-linear curve for the induction of chromosome aberrations, detected by anaphase method. After irradiation in S-stage of the cell cycle at dose below 0.2 Gy the cells were more radiosensitive than after irradiation with doses 0.3-2 Gy. Between the phases of high radiosensitivity and radioresistance the reversal dose-effect relation was observed. This phenomenon was not marked for the cells after irradiation in G2-stage of the cell cycle. It is possible, this results could reflect an induced radioresistance at low dose of irradiation.
Shmakova
N L
NL
Joint Institute for Nuclear Research, Dubna, Russia.
Fadeeva
T A
TA
Krasavin
E A
EA
D000818:Animals; D002460:Cell Line; D002869:Chromosome Aberrations; D003037:Cobalt Radioisotopes / Q000494:pharmacology; D006224:Cricetinae; D003412:Cricetulus; D004307:Dose-Response Relationship, Radiation; D016195:G2 Phase; D005720:Gamma Rays; D011829:Radiation Dosage; D011836:Radiation Tolerance; D013997:Time Factors
D003037:Cobalt Radioisotopes