Clonal chromosome abnormalities in a so-called Dupuytren's subungual exostosis.
We report the first cytogenetic investigation of a Dupuytren's subungual exostosis. The clonal abnormalities found suggest that at least some of these heterotopic ossifications could be neoplastic in nature, instead of being a purely reactive process or exuberant growth in response to trauma.
Dal Cin
P
P
Center for Human Genetics, University of Leuven, Belgium.
Pauwels
P
P
Poldermans
L J
LJ
Sciot
R
R
Van den Berghe
H
H
D000293:Adolescent; D002478:Cells, Cultured; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002877:Chromosomes, Human / Q000235:genetics*; D002999:Clone Cells; D004387:Dupuytren Contracture / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male