title: [Identification of alloantibodies associated with an autoantibody: profile of 2 quality control programs in French blood transfusion facilities].
abstract: The French Blood Transfusion Society working group Immunohaematology and the French Blood Transfusion Center of Lille performed two quality control exercises-96-01 and 97-02-in order to evaluate identification performances of alloantibodies associated with an autoantibody recognizing a high frequency antigen. Concerning control 96-01, 83 (75%) of the 110 blood transfusion centers participating at this exercise sent results. The alloantibody screening was correct for 78 of them (94%). Sixty-one (78%) blood transfusion centers correctly identified the specificities (anti-RH1 + anti-FY1). Concerning control 97-02, 82 (94%) of the 87 blood transfusion centers participating in this exercise sent results. The alloantibody screening was correct for 69 (88%) of them. Fifty-three blood transfusion centers (77%) correctly identified the specificities (anti-RH3 + anti-FY1). These exercises allowed us to confirm the main procedures used in routine for national scale testing. The analysis of the results has underlined the importance of these tests for assessing the quality of these examinations, and highlighted the means to be carried out in order to improve them.
authors.affiliation: Etablissement de transfusion sanguine du Nord-Pas-de-Calais, Lille, France.
authors.forename: L
authors.initials: L
authors.lastname: Mannessier
authors.forename: A
authors.initials: A
authors.lastname: Delsalle
mesh_terms: D000888:Antibodies, Anti-Idiotypic / Q000276:immunology*; D000918:Antibody Specificity; D001323:Autoantibodies / Q000276:immunology*; D001771:Blood Banks / Q000458:organization & administration / Q000592:standards*; D002850:Chromatography, Gel; D003298:Coombs Test; D004375:Duffy Blood-Group System / Q000276:immunology*; D005602:France; D006462:Hemolytic Plaque Technique; D006801:Humans; D007163:Immunosorbent Techniques; D007518:Isoantibodies / Q000097:blood* / Q000276:immunology; D008403:Mass Screening / Q000379:methods / Q000592:standards*; D009500:Neutralization Tests; D015397:Program Evaluation; D011785:Quality Assurance, Health Care / Q000458:organization & administration*; D011786:Quality Control; D012204:Rh-Hr Blood-Group System / Q000276:immunology*; D012680:Sensitivity and Specificity
chemical_list: D000888:Antibodies, Anti-Idiotypic; D001323:Autoantibodies; D004375:Duffy Blood-Group System; D007518:Isoantibodies; D012204:Rh-Hr Blood-Group System