title: [Helicobacter pylori infections in children in the tropical zone. Endoscopic and histological aspects].
abstract: OBJECTIVE
  To assess the endoscopic and histological aspects of Helicobacter pylori (H. pylori) infection in children in a prospective study.
  
  
  METHODS
  One hundred and four children (6 months-15 years old), with digestive symptoms admitted to the Pediatric Department of the National Hospital of Ouagadougou between February Ist and October 31 1996, underwent upper digestive endoscopy with fundic and antral biopsies for histological and bacteriological analysis.
  
  
  RESULTS
  Endoscopy was normal in 80 cases (77%). No lesion was specific of H. pylori infection. Nodular gastritis was observed in 3% of the cases only. Duodenal ulcers were seen in 3 children (3%). 83% of the children had chronic antral gastritis, associates with H. pylori in 95% of the cases. The lesions were follicular gastritis (45%), mild atrophic gastritis (38.5%) and lymphocytic gastritis (1%). Follicular gastritis was more pronounced in the antrum than in the fundus.
  
  
  CONCLUSIONS
  The high prevalence of early H. pylori infection and chronic gastritis in children contrasts with the rarity of gastric cancer in black Africa. Protective factors or peculiar strains should be searched for.
authors.affiliation: Service de Gastroentérologie, Hôpital National, Ouagadougou, Burkina Faso.
authors.forename: D
authors.initials: D
authors.lastname: Ilboudo
authors.forename: A
authors.initials: A
authors.lastname: Bougouma
authors.forename: R
authors.initials: R
authors.lastname: Sombie
authors.forename: A
authors.initials: A
authors.lastname: Sawadogo
authors.forename: I
authors.initials: I
authors.lastname: Sanou
authors.forename: I
authors.initials: I
authors.lastname: Diomande
mesh_terms: D000293:Adolescent; D001706:Biopsy; D002050:Burkina Faso; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D005756:Gastritis / Q000145:classification / Q000382:microbiology* / Q000473:pathology*; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000150:complications*; D016480:Helicobacter pylori; D006801:Humans; D007223:Infant; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D014329:Tropical Climate