title: [Prognostic factors and the effect of radiotherapy in the treatment of differentiated thyroid carcinomas].
abstract: OBJECTIVE
  In the treatment of differentiated thyroid carcinomas the indication for adjuvant radiotherapy is discussed contradictory. The following study analyzes the long-term survival rates of patients with follicular and papillar thyroid carcinomas after percutaneous radiotherapy.
  
  
  METHODS
  Records of 178 patients with differentiated thyroid carcinomas (132 female, median age 46 years; 46 male, median age 47 years) were evaluated. Following thyroid-resection and radioiodine therapy external beam irradiation was performed with a telecobalt device and high energy electrons (mean reference dose 54.7 Gy). Hundred and twenty patients (67.4%) had a histologically confirmed papillary carcinoma, 58 (32.6%) patients had follicular carcinoma. In the group with papillary carcinoma 57 patients (47.5%) were classified as stage I, 11 patients (9.2%) as stage II, 48 patients (40.0%) as stage III, 4 patients (3.3%) as stage IV, respectively, in the group with follicular carcinoma 21 patients (36.2%) were classified as stage I, 4 patients (6.9%) as stage II, 28 patients (48.3%) as stage III and 5 patients (8.6%) as stage IV. Survival, recurrence rate and prognostic factors were analyzed.
authors.affiliation: Klinik für Strahlentherapie und Radio-Onkologie, Ruhr-Universität-Bochum, Marienhospital Herne. Irenaeus.A.Adamietz@ruhr-uni-bochum.de
authors.forename: I A
authors.initials: IA
authors.lastname: Adamietz
authors.forename: M S
authors.initials: MS
authors.lastname: Schiemann
authors.forename: J G
authors.initials: JG
authors.lastname: Petkauskas
authors.forename: F
authors.initials: F
authors.lastname: Schemmann
authors.forename: H D
authors.initials: HD
authors.lastname: Böttcher
mesh_terms: D002277:Carcinoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D004583:Electrons / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D011867:Radioisotope Teletherapy; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D015996:Survival Rate; D013964:Thyroid Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D013965:Thyroidectomy
chemical_list: D003037:Cobalt Radioisotopes; D007457:Iodine Radioisotopes