[Intra-cord injection of autologous fatty tissue and recurrent unilateral paralysis].
A prospective analysis of intracordal autologous fat injection for inferior laryngeal nerve paralysis of various origins was conducted in a series of 20 patients with a minimum 6 month follow-up. Adverse side effects were a sub-cutaneous abdominal hematoma, and a pseudo intracordal cyst in 1 patient. Aspiration, noted in 11 patients, disappeared immediately after the injection of fat in 10 patients. Subjective evaluation and objective acoustic recordings documented improvement in voice quality at 6 months. Three patients had a secondary reinjection of fat resulting in an overall 100% success rate. Such preliminary data, together with the review of the literature suggests, that intracordal autologous fat injection is a highly valuable treatment option in patients with unilateral inferior nerve paralysis.
Laccourreye
O
O
Service d'Oto-Rhino-Laryngologie, Hôpital Laennec, Assistance Publique des Hôpitaux de Paris, Université Paris V.
Crevier-Buchman
L
L
Bou-Malhab
F
F
Hans
S
S
Biacabe
B
B
Brasnu
D
D
D000005:Abdomen; D000273:Adipose Tissue / Q000637:transplantation*; D000328:Adult; D000368:Aged; D003560:Cysts / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006406:Hematoma / Q000209:etiology; D006801:Humans; D007267:Injections; D007818:Laryngeal Diseases / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D019106:Postoperative Hemorrhage / Q000209:etiology; D011446:Prospective Studies; D012008:Recurrence; D012086:Reoperation; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000601:surgery*; D014827:Vocal Cords / Q000601:surgery*; D014832:Voice Disorders / Q000601:surgery; D014833:Voice Quality