title: Immunity to pertussis. Not all virulence factors are protective antigens.
abstract: As with diphtheria, immunity to pertussis is complex because it involves both individual and community protection against infection with B. pertussis. Although B. pertussis has at least five proteins required for virulence and an additional two "toxic" components, only serum neutralizing antibodies to PT (antitoxin) have been shown to confer immunity to pertussis.
authors.affiliation: National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors.forename: J B
authors.initials: JB
authors.lastname: Robbins
authors.forename: R
authors.initials: R
authors.lastname: Schneerson
authors.forename: D A
authors.initials: DA
authors.lastname: Bryla
authors.forename: B
authors.initials: B
authors.lastname: Trollfors
authors.forename: J
authors.initials: J
authors.lastname: Taranger
authors.forename: T
authors.initials: T
authors.lastname: Lagergård
mesh_terms: D001886:Bordetella pertussis / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D010567:Pertussis Vaccine / Q000276:immunology* / Q000627:therapeutic use; D014917:Whooping Cough / Q000276:immunology* / Q000503:physiopathology / Q000517:prevention & control
chemical_list: D010567:Pertussis Vaccine