[Migration capacity of phagocytes during simulation of some spaceflight factors under the terrestrial conditions].
Migration activity of the leukocytes featuring the functional state and metabolic activity of immunocompetent cells was studied. Migration of phagocyting cells was explored in 8 female test-subjects in the course of 120-day head-down bed rest and 3 male volunteers isolated in a hermetically sealed room over a similar period. Bed rest without use of preventive measures decreased significantly the migration activity of leukocytes; on the opposite, administration of the preventive measures by the bedrested subjects doubled the parameter. In the experiment with the long-term isolation the activity of leukocytes decreased significantly.
Meshkov
D O
DO
Rykova
M P
MP
Belozerova
I N
IN
D001510:Bed Rest; D002464:Cell Migration Inhibition; D002634:Chemotaxis, Leukocyte / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D018475:Head-Down Tilt / Q000502:physiology; D006801:Humans; D018476:Hypokinesia / Q000097:blood / Q000209:etiology; D007962:Leukocytes / Q000502:physiology; D008297:Male; D010586:Phagocytes / Q000502:physiology*; D013026:Space Flight; D018561:Space Simulation