title: T-cell activation: interplay at the interface.
abstract: Recent studies have shown that, when a T cell interacts with a cognate antigen-presenting cell, an organized adhesive contact is formed between the two cells by a process which involves the dynamic, three-dimensional redistribution of entire signaling assemblies.
authors.affiliation: Human Immunology Section, Experimental Immunology Branch, Building 10, Room 4B36, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-1360, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Brown
authors.forename: S
authors.initials: S
authors.lastname: Shaw
mesh_terms: D000938:Antigen-Presenting Cells / Q000276:immunology*; D002448:Cell Adhesion / Q000276:immunology; D016023:Integrins / Q000378:metabolism; D008213:Lymphocyte Activation / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D016023:Integrins