The origin of red blood cell biopterin.
Data are presented to support the hypothesis that the biopterin content of red blood cells arises during erythropoiesis. Only when the plasma concentration rises above the erythrocyte concentration of biopterin is there likely to be diffusion into the cell.
Leeming
R J
RJ
Department of Clinical Chemistry, The Birmingham Children's Hospital NHS Trust, Steelhouse Lane, Birmingham, B4 6NH, United Kingdom.
Hall
S K
SK
Green
A
A
D000328:Adult; D000592:Amino Acid Metabolism, Inborn Errors / Q000097:blood; D001708:Biopterins / Q000097:blood*; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D010649:Phenylalanine / Q000097:blood / Q000378:metabolism / Q000494:pharmacology; D010661:Phenylketonurias / Q000097:blood* / Q000188:drug therapy
D001708:Biopterins; D010649:Phenylalanine