title: Quantitative analysis of penile ultrasonographic shape during the erectile cycle: a new diagnostic tool for erectile dysfunction? Repeatability of the method and preliminary results.
abstract: Penile modifications during erection interest not only penile length and circumference, but also its size and shape. In this investigation, the size and shape repeatability of a single standardized ultrasonographic image of penis during flaccidity and erection was quantified in a group of 19 patients complaining of erectile dysfunction. The penis of each patient was placed in the dorsal position and scanned by a 10 MHz linear ultrasonographic probe at the site of maximal corporeal size: (1) during flaccidity; (2) after an intracorporeal injection of 10 micrograms alprostadil; and (3) after a genital stimulation. Each scan was repeated three times for each patient and printed. On each print the outline of the tunica albuginea was drawn, digitized, and mathematically reconstructed by Fourier series that allow a separate quantification of the size and shape differences. Reliability of the tunica albuginea outline and repeatability of probe positioning were separately assessed within patient and functional phase, and found to be good. The actual examinations of two impotence patients performed using the described method are also given. The shape of the corpora cavernosa may be potentially indicative of the homogeneous function of the tunica albuginea, and it may be of use in patients' follow up.
authors.affiliation: Functional Anatomy Research Center (FARC), Milan, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Sforza
authors.forename: F
authors.initials: F
authors.lastname: Montorsi
authors.forename: A
authors.initials: A
authors.lastname: Bianchi
authors.forename: V F
authors.initials: VF
authors.lastname: Ferrario
mesh_terms: D000328:Adult; D000368:Aged; D000527:Alprostadil; D007172:Erectile Dysfunction / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005583:Fourier Analysis; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D010410:Penile Erection; D010413:Penis / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000503:physiopathology; D015203:Reproducibility of Results; D014463:Ultrasonography; D014665:Vasodilator Agents
chemical_list: D014665:Vasodilator Agents; D000527:Alprostadil