title: Contralateral solitary testis metastasis antedating renal cell carcinoma: a case-report and review.
abstract: A 56-year-old Caucasian smoker male patient underwent right orchiectomy and spermatic cord resection for intrascrotal transilluminating mass. Histology findings suggested diagnosis of metastasis from Renal Cell Carcinoma (RCC). After positive CT-scan for primary neoplasm, total left nephrectomy was accomplished. Patient referred to our institution and started interferon immunotherapy; nowadays, after 21 months is disease free and in good health. We have reviewed and summarized the international literature regarding testicular metastasis from renal cell carcinoma; this is the first case of histology-proved-RCC ("clear cell" type)-solitary-contralateral-testicular-recurrence antedating clinical evidence of the primary neoplasm, which underwent orchiectomy before nephrectomy.
authors.affiliation: Dipartimento di Medicina Sperimentale e Patologia, Università La Sapienza, Rome, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Lauro
authors.forename: G
authors.initials: G
authors.lastname: Lanzetta
authors.forename: E
authors.initials: E
authors.lastname: Bria
authors.forename: L
authors.initials: L
authors.lastname: Trasatti
authors.forename: L
authors.initials: L
authors.lastname: Costarelli
authors.forename: A
authors.initials: A
authors.lastname: Vecchione
mesh_terms: D002292:Carcinoma, Renal Cell / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009392:Nephrectomy; D009919:Orchiectomy; D013085:Spermatic Cord / Q000601:surgery; D013736:Testicular Neoplasms / Q000473:pathology* / Q000556:secondary* / Q000601:surgery