[How I study a patient with a low concentration of HDL cholesterol].
A decrease in plasma HDL cholesterol concentration is considered as a major cardiovascular risk factor and is a prevalent lipid abnormality among patients with coronary heart disease. This condition is most often observed in the presence of hypertriglyceridaemia, generally linked to the insulin resistance syndrome, but may also be associated to elevated LDL cholesterol level or even be present alone (hypoalphalipoproteinaemia). The decision to treat a patient with low HDL level depends on the individual overall cardiovascular risk which should be evaluated as carefully as possible. The investigation should look for causes which may favour this metabolic condition, such as bad life habits or possible pharmacological interferences.
Scheen
A J
AJ
Université de Liège.
D008076:Cholesterol, HDL / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood; D003327:Coronary Disease / Q000097:blood; D004347:Drug Interactions; D064420:Drug-Related Side Effects and Adverse Reactions; D006331:Heart Diseases / Q000209:etiology; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000150:complications; D015228:Hypertriglyceridemia / Q000150:complications; D007009:Hypolipoproteinemias / Q000097:blood / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D007333:Insulin Resistance; D008019:Life Style; D012307:Risk Factors
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL