title: Breast-feeding of allergic infants.
abstract: OBJECTIVE
  Infants may have allergic disease even during exclusive breast-feeding. The aim of this study was to evaluate whether allergic infants should continue breast-feeding.
  
  
  METHODS
  We studied 100 infants who had atopic eczema during exclusive breast-feeding. The extent and severity of the eczema, allergic sensitization, and the patients' growth and nutrition were assessed during and after cessation of breast-feeding.
  
  
  RESULTS
  The mean body length SD score decreased at the onset of allergic disease, and an association was seen between the duration of symptoms and poor growth (r = -.23, P =.04). Some improvement could be achieved by strict elimination diet by the mothers. The atopic eczema improved significantly after breast-feeding was stopped: SCORAD score 20 (range 15 to 27) during and 7 (range 4 to 11) after breast-feeding; t = 5.38, P <.0001, and the relative length of patients increased, in parallel with improved nutritional parameters.
  
  
  CONCLUSIONS
  Breast-feeding should be promoted for primary prevention of allergy, but breast-fed infants with allergy should be treated by allergen avoidance, and in some cases breast-feeding should also be stopped. This particularly applies to infants with atopic eczema who also have impaired growth.
authors.affiliation: Department of Pediatrics, University of Turku, Finland.
authors.forename: E
authors.initials: E
authors.lastname: Isolauri
authors.forename: A
authors.initials: A
authors.lastname: Tahvanainen
authors.forename: T
authors.initials: T
authors.lastname: Peltola
authors.forename: T
authors.initials: T
authors.lastname: Arvola
mesh_terms: D001942:Breast Feeding / Q000009:adverse effects* / Q000523:psychology; D002657:Child Development; D003876:Dermatitis, Atopic / Q000145:classification / Q000209:etiology*; D004032:Diet; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008895:Milk, Human / Q000737:chemistry*; D009035:Mothers / Q000523:psychology; D009752:Nutritional Status; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D014886:Weaning