title: Three-dimensional MR coronary angiography using the navigator technique compared with conventional coronary angiography.
abstract: OBJECTIVE
  We evaluated the diagnostic accuracy of three-dimensional (3D) MR coronary angiography with the navigator technique for the detection of coronary artery stenoses in comparison with that of conventional radiographic angiography.
  
  
  METHODS
  Thirty patients with coronary artery disease were examined with an ECG-triggered 3D fast low-angle shot sequence using retrospective respiratory gating and the navigator technique on a 1.5-T MR scanner. The data set was evaluated as a 3D view with a surface rendering technique.
  
  
  RESULTS
  Imaging of the proximal coronary arteries was possible in all patients. The average visualized lengths of the left main, left anterior descending, left circumflex, and right coronary arteries were 1.9+/-0.5 cm (mean +/- SD), 5.2+/-2.3 cm, 4.2+/-1.9 cm, and 5.2+/-2.5 cm, respectively. Irregular breathing reduced image quality in seven of the 30 patients, making diagnosis of stenoses impossible. In the 77% of patients whose examinations resulted in high-quality images, the sensitivity and specificity for detection of significant stenoses and occlusions in all four main coronary arteries were 81% and 89%, respectively.
  
  
  CONCLUSIONS
  The navigator technique allows reproducible imaging of the proximal course of coronary arteries. This technique obviates breath-hold studies, thus allowing more patients to be examined. In patients whose examinations resulted in high-quality images, significant coronary artery lesions could be seen. However, for widespread clinical use, further technical improvement is necessary to increase sensitivity and specificity.
authors.affiliation: Institut für Röntgendiagnostik, Universität Würzburg, Germany.
authors.forename: J J
authors.initials: JJ
authors.lastname: Sandstede
authors.forename: T
authors.initials: T
authors.lastname: Pabst
authors.forename: M
authors.initials: M
authors.lastname: Beer
authors.forename: N
authors.initials: N
authors.lastname: Geis
authors.forename: W
authors.initials: W
authors.lastname: Kenn
authors.forename: S
authors.initials: S
authors.lastname: Neubauer
authors.forename: D
authors.initials: D
authors.lastname: Hahn
mesh_terms: D000328:Adult; D000368:Aged; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity