Utility of PCR assay in diagnosis of en-plaque tuberculoma of the brain.
This is the first report of a case in which diagnosis of en-plaque tuberculoma on the basis of magnetic resonance imaging (MRI) findings was confirmed by a Mycobacterium tuberculosis complex-specific PCR assay of cerebrospinal fluid. The accuracy of the diagnosis was supported by good response to antitubercular drugs, which was shown by repeat MRI studies performed after treatment.
Singh
K K
KK
Department of Biotechnology, All India Institute of Medical Sciences, New Delhi, India.
Nair
M D
MD
Radhakrishnan
K
K
Tyagi
J S
JS
D000995:Antitubercular Agents / Q000627:therapeutic use; D001921:Brain / Q000473:pathology; D002555:Cerebrospinal Fluid / Q000382:microbiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D012680:Sensitivity and Specificity; D016862:Tuberculoma, Intracranial / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology
D000995:Antitubercular Agents