title: One-site versus 2-site phacotrabeculectomy: a randomized study.
abstract: OBJECTIVE
  To compare 1-site and 2-site combined phacoemulsification with foldable intraocular lens (IOL) implantation and trabeculectomy.
  
  
  METHODS
  El-Maghraby Eye Hospital, Jeddah, Saudi Arabia.
  
  
  METHODS
  Seventy-six eyes with coexisting cataract and glaucoma were randomly assigned to have a mitomycin-C trabeculectomy in a superior quadrant combined with phacoemulsification and foldable IOL implantation through the same incision (1-site group) or a separate, temporal, clear corneal incision (2-site group). Postoperative evaluation included visual acuity, intraocular pressure (IOP), bleb assessment, and number of antiglaucoma medications. Follow-up ranged from 12 to 18 months.
  
  
  RESULTS
  Mean preoperative IOP was 28.1 mm Hg +/- 7.1 (SD) in the 2-site group and 26.2 +/- 6.5 mm Hg in the 1-site group. At 6 months postoperatively, mean IOP was 16.9 +/- 4.3 and 16.8 +/- 3.8 mm Hg, respectively (P = .9) and at 12 months, 17.6 +/- 3.3 and 19.1 +/- 3.1 mm Hg, respectively (P = .044). Twenty-three of 39 eyes (59%) in the 2-site group and 14 of 37 (38%) in the 1-site group had clinically apparent filtering blebs at 12 months (P = .065). Postoperative astigmatic change and complications were comparable.
  
  
  CONCLUSIONS
  Mitomycin-C trabeculectomy superiorly combined with separate temporal clear corneal phacoemulsification provided 1 year IOP control comparable to that with single-incision (1-site) combined cataract and glaucoma surgery.
authors.affiliation: El-Maghraby Eye Hospital, Jeddah, Saudi Arabia.
authors.forename: F
authors.initials: F
authors.lastname: el Sayyad
authors.forename: M
authors.initials: M
authors.lastname: Helal
authors.forename: A
authors.initials: A
authors.lastname: el-Maghraby
authors.forename: M
authors.initials: M
authors.lastname: Khalil
authors.forename: H
authors.initials: H
authors.lastname: el-Hamzawey
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019923:Capsulorhexis; D002386:Cataract / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000150:complications* / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D011183:Postoperative Complications; D012826:Silicone Elastomers; D014130:Trabeculectomy / Q000379:methods*; D014792:Visual Acuity
chemical_list: D012826:Silicone Elastomers