title: Somatostatin receptor scintigraphy and somatostatin therapy in the evaluation and treatment of malignant thymoma.
abstract: OBJECTIVE
  This report illustrates the potential diagnostic and therapeutic utility of somatostatin receptor scintigraphy and therapy with somatostatin.
  
  
  METHODS
  In-111 pentetreotide (In-111 octreotide), a somatostatin analog, was used to define the receptor status and the extent of disease in a case of malignant thymoma.
  
  
  RESULTS
  Subsequent treatment with nonradioactive somatostatin inhibited tumor growth.
  
  
  CONCLUSIONS
  In-111 octreotide may be useful to define tumor receptor status and may provide prognostic information useful in determining subsequent therapy.
authors.affiliation: Department of Radiology and Radiological Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA.
authors.forename: K
authors.initials: K
authors.lastname: Lin
authors.forename: B D
authors.initials: BD
authors.lastname: Nguyen
authors.forename: D S
authors.initials: DS
authors.lastname: Ettinger
authors.forename: B B
authors.initials: BB
authors.lastname: Chin
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006727:Hormone Antagonists / Q000627:therapeutic use*; D006801:Humans; D007205:Indium Radioisotopes; D008479:Mediastinal Neoplasms / Q000556:secondary; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009367:Neoplasm Staging; D015282:Octreotide / Q000031:analogs & derivatives; D010997:Pleural Neoplasms / Q000556:secondary; D011379:Prognosis; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin / Q000032:analysis*; D013004:Somatostatin / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D013945:Thymoma / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology / Q000556:secondary; D013953:Thymus Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology
chemical_list: D006727:Hormone Antagonists; D007205:Indium Radioisotopes; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin; C094279:indium-111-octreotide; D013004:Somatostatin; C081788:pentetreotide; D015282:Octreotide