title: Bilateral optic neuritis in acute human immunodeficiency virus infection.
abstract: OBJECTIVE
  To report a case of acute viral disease accompanied by bilateral optic neuritis with substantial paraclinical evidence that human immunodeficiency virus was the causative agent.
  
  
  METHODS
  Clinical and paraclinical examination. Magnetic resonance imaging.
  
  
  RESULTS
  Virus and antibody titers as well as reverse lymphocytosis were consistent with acute infection by the human immunodeficiency virus-1.
  
  
  CONCLUSIONS
  Human immunodeficiency virus infection should be considered in the differential diagnosis of acute optic neuritis.
authors.affiliation: Department of Ophthalmology, Rigshospitalet, Copenhagen, Denmark. oculus@post1.dknet.dk
authors.forename: M
authors.initials: M
authors.lastname: Larsen
authors.forename: P B
authors.initials: PB
authors.lastname: Toft
authors.forename: P
authors.initials: P
authors.lastname: Bernhard
authors.forename: M
authors.initials: M
authors.lastname: Herning
mesh_terms: D000208:Acute Disease; D000212:Acyclovir / Q000627:therapeutic use; D000328:Adult; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D005260:Female; D015483:HIV Antibodies / Q000032:analysis; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D015497:HIV-1 / Q000235:genetics / Q000276:immunology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009900:Optic Nerve / Q000473:pathology; D009902:Optic Neuritis / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D016133:Polymerase Chain Reaction; D011239:Prednisolone / Q000627:therapeutic use; D012367:RNA, Viral / Q000032:analysis
chemical_list: D015483:HIV Antibodies; D012367:RNA, Viral; D011239:Prednisolone; D000212:Acyclovir