title: [Intra-cord injection of autologous fatty tissue and recurrent unilateral paralysis].
abstract: A prospective analysis of intracordal autologous fat injection for inferior laryngeal nerve paralysis of various origins was conducted in a series of 20 patients with a minimum 6 month follow-up. Adverse side effects were a sub-cutaneous abdominal hematoma, and a pseudo intracordal cyst in 1 patient. Aspiration, noted in 11 patients, disappeared immediately after the injection of fat in 10 patients. Subjective evaluation and objective acoustic recordings documented improvement in voice quality at 6 months. Three patients had a secondary reinjection of fat resulting in an overall 100% success rate. Such preliminary data, together with the review of the literature suggests, that intracordal autologous fat injection is a highly valuable treatment option in patients with unilateral inferior nerve paralysis.
authors.affiliation: Service d'Oto-Rhino-Laryngologie, Hôpital Laennec, Assistance Publique des Hôpitaux de Paris, Université Paris V.
authors.forename: O
authors.initials: O
authors.lastname: Laccourreye
authors.forename: L
authors.initials: L
authors.lastname: Crevier-Buchman
authors.forename: F
authors.initials: F
authors.lastname: Bou-Malhab
authors.forename: S
authors.initials: S
authors.lastname: Hans
authors.forename: B
authors.initials: B
authors.lastname: Biacabe
authors.forename: D
authors.initials: D
authors.lastname: Brasnu
mesh_terms: D000005:Abdomen; D000273:Adipose Tissue / Q000637:transplantation*; D000328:Adult; D000368:Aged; D003560:Cysts / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006406:Hematoma / Q000209:etiology; D006801:Humans; D007267:Injections; D007818:Laryngeal Diseases / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D019106:Postoperative Hemorrhage / Q000209:etiology; D011446:Prospective Studies; D012008:Recurrence; D012086:Reoperation; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000601:surgery*; D014827:Vocal Cords / Q000601:surgery*; D014832:Voice Disorders / Q000601:surgery; D014833:Voice Quality