title: On the antioxidant activity of melatonin.
abstract: Melatonin has been widely reported to be an effective antioxidant. Studies of its ability to inhibit the autoxidation of lipids in homogeneous solution and in model heterogeneous systems show that melatonin is not a peroxyl radical trapping antioxidant. In contrast, melatonin can inhibit metal ion-catalyzed oxidation processes.
authors.affiliation: Grupo de Bioquimica e Biologia Teóricas, Bento da Rocha Cabral, Lisbon, Portugal.
authors.forename: F
authors.initials: F
authors.lastname: Antunes
authors.forename: L R
authors.initials: LR
authors.lastname: Barclay
authors.forename: K U
authors.initials: KU
authors.lastname: Ingold
authors.forename: M
authors.initials: M
authors.lastname: King
authors.forename: J Q
authors.initials: JQ
authors.lastname: Norris
authors.forename: J C
authors.initials: JC
authors.lastname: Scaiano
authors.forename: F
authors.initials: F
authors.lastname: Xi
mesh_terms: D000975:Antioxidants / Q000378:metabolism* / Q000494:pharmacology*; D005609:Free Radicals / Q000378:metabolism; D066298:In Vitro Techniques; D008051:Lipid Bilayers; D050356:Lipid Metabolism; D008550:Melatonin / Q000378:metabolism* / Q000494:pharmacology*; D008823:Micelles; D010084:Oxidation-Reduction; D010545:Peroxides / Q000378:metabolism; D012996:Solutions; D013050:Spectrometry, Fluorescence
chemical_list: D000975:Antioxidants; D005609:Free Radicals; D008051:Lipid Bilayers; D008823:Micelles; D010545:Peroxides; D012996:Solutions; C049375:perhydroxyl radical; D008550:Melatonin