title: Brown fat necrosis in the setting of congenital heart disease and prostaglandin E1 use: a case report.
abstract: We report a case of a child with D-transposition of the great arteries treated with prostaglandin E1 (PGE1) who subsequently developed extensive brown fat necrosis. To the best of our knowledge, no previous association among congenital heart disease, PGE1, and brown fat necrosis has been reported.
authors.affiliation: Department of Radiology, The University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Raboi
authors.forename: W
authors.initials: W
authors.lastname: Smith
mesh_terms: D002001:Adipose Tissue, Brown / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology*; D000527:Alprostadil / Q000009:adverse effects*; D003240:Connective Tissue Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D009336:Necrosis; D010166:Palliative Care; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed; D014665:Vasodilator Agents / Q000009:adverse effects*
chemical_list: D014665:Vasodilator Agents; D000527:Alprostadil