[Hypertension and dyslipidemia].
Hypertension is a very important cardiovascular risk factor and directly leads to major atherosclerotic cardiovascular diseases, including coronary artery disease, stroke cardiac failure and peripheral artery disease. Hypertension tends to cluster with other atherogenic risk factors like dyslipidemia, insulin resistance, obesity and others. The association between hypertension and dyslipidemia is very frequent and the risk is more than additive and its possible pathogenesis may be of a common mechanism. Insulin resistance is the main cause of both risk factors. Endothelium dysfunction is present in arterial hypertension and dyslipidemia and the pathogenesis of atherosclerosis. The treatment of hypertensive patients must be individualized to accommodate both the concomitant dyslipidemia and other atherogenic factors.
de Lombera Romero
F
F
Servicio de Cardiología, Hospital 12 de Octubre, Madrid.
Fernández Casares
S
S
Gascueña Rubia
R
R
Lázaro
M
M
Hernández Simón
P
P
Saavedra Falero
J
J
Sánchez Sánchez
V
V
Velázquez Martín
M T
MT
García Pascual
J
J
Sáenz de la Calzada
C
C
D001161:Arteriosclerosis / Q000150:complications; D004041:Dietary Fats / Q000008:administration & dosage; D004730:Endothelium, Vascular / Q000503:physiopathology; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications* / Q000628:therapy; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy; D007333:Insulin Resistance; D012307:Risk Factors
D004041:Dietary Fats