title: [A case of brain abscess accompanied with sudden-onset hemiplegia as initial manifestation].
abstract: A 58-year-old male experienced a sudden stroke-like onset of right hemiplegia and numbness of his right upper limb while engaged in his desk-work on April 7, 1997. He had a past history of diabetes mellitus and hyperlipidemia. On admission, he had no fever and the blood pressure was 140/70 mmHg. General physical examination was unremarkable. Neurological examination showed 4/5 strength of his right unilateral extremities and numbness of his right upper limb. Clinical features and computed tomography (CT) without contrast medium at the onset of hemiplegia suggested a stroke. Seven days after admission, his consciousness worsened and body temperature fluctuated between 37 and 38 degrees C. Subsequent Gd-enhanced magnetic resonance (MR) which demonstrated an irregular shaped ring-enhancement lesion and lumbar puncture 9 days after admission was compatible with the diagnosis of brain abscess. Surgical drainage confirmed the presence of brain abscess due to alpha-streptococcus. It improved following surgical drainage and antibiotic therapy with PAPM.BP 2 g/day and PIPC 4 g/day. An afebrile patient of sudden stroke-like onset may be a rarity to be added to the differential diagnosis of brain abscess.
authors.affiliation: Department of Internal Medicine, Kawasaki Municipal Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Okubo
authors.forename: N
authors.initials: N
authors.lastname: Koido
authors.forename: M
authors.initials: M
authors.lastname: Obana
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuoka
authors.forename: S
authors.initials: S
authors.lastname: Irimajiri
mesh_terms: D000208:Acute Disease; D001922:Brain Abscess / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D006429:Hemiplegia / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012772:Shock, Septic / Q000209:etiology; D013290:Streptococcal Infections / Q000150:complications* / Q000175:diagnosis; D013297:Streptococcus pyogenes