title: Arterial embolization of bone metastases: is it worthwhile?
abstract: Arterial embolization was performed in ten skeletal metastases occurring in nine patients: eight patients presented with renal cell carcinoma and one with bronchogenic carcinoma. Five metastatic lesions were located in the spine, one in the pelvis, three in the proximal humerus and one in the proximal femur. Selective arterial embolization was performed preoperatively in seven cases and as a palliative treatment in three cases. The embolic material used was polyvinyl alcohol particles, gelatin sponge and coils or a combination of these. Arterial embolization was technically successful in all patients achieving subtotal (> 90%) tumour devascularization in five metastases and a 75% devascularization in the remaining five lesions. In operative patients, median intra-operative volume of blood transfusion was 510 mL. Palliative embolization was followed by major pain relief in two cases and moderate relief in one case lasting from 7 to 26 months. Arterial embolization is an effective and safe adjunctive treatment of hypervascular bone metastases.
authors.affiliation: Department of Medical Imaging, University Hospital Sart Tilman, Liège, Belgium.
authors.forename: I
authors.initials: I
authors.lastname: Layalle
authors.forename: P
authors.initials: P
authors.lastname: Flandroy
authors.forename: G
authors.initials: G
authors.lastname: Trotteur
authors.forename: R F
authors.initials: RF
authors.lastname: Dondelinger
mesh_terms: D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary / Q000628:therapy*; D002283:Carcinoma, Bronchogenic / Q000556:secondary / Q000628:therapy*; D002292:Carcinoma, Renal Cell / Q000556:secondary / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged