Clathrin: a good view of a shapely leg.
The crystal structure of an amino-terminal fragment of the clathrin heavy chain has recently been determined, revealing a globular beta-propeller domain attached by an alpha-zig-zag connecting rod to the heavy chain's distal segment. The structure sheds interesting new light on the design features of this versatile protein.
Ungewickell
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Department of Cell Biology, Centre of Anatomy, Medical School, Hannover Carl-Neuberg Strasse, 1 D 30625, Hannover, Germany.
D002966:Clathrin / Q000737:chemistry* / Q000648:ultrastructure; D008854:Microscopy, Electron / Q000379:methods; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary
D002966:Clathrin