[Localized diffuse pulmonary AL-amyloidosis].
A 56 year-old woman was admitted due to exertional dyspnoea. Her chest x-ray and CT scanning showed widespread diffuse infiltrative changes in both lungs, associated with a pronounced decrease in diffusion capacity. Transbronchial biopsies showed primary (AL) amyloidosis. Systemic AL-amyloidosis was excluded and diagnosis of localised diffuse parenchymal pulmonary amyloidosis was established. Treatment with prednisolone and melphalan for one year has stabilised the condition. Lung transplantation will be considered in case of deterioration.
Abdulla
J
J
Amtssygehuset i Gentofte, lungemedicinsk afdeling Y.
Maltboek
N
N
Birgens
H
H
D000686:Amyloidosis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000276:immunology; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000276:immunology; D008558:Melphalan / Q000627:therapeutic use; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D000893:Anti-Inflammatory Agents; D011239:Prednisolone; D008558:Melphalan