title: Early results of AV sequential pacing on left ventricular outflow obstruction after Senning procedure.
abstract: Dual chamber pacing was shown to decrease left ventricular outflow tract (LVOT) obstruction in patients with hypertrophic cardiomyopathy 30 years ago. We report early results of AV sequential pacing from the LV apex in a patient with transposition of the great arteries who is post-Senning procedure. LVOT obstruction resulted from septal deviation and systolic anterior motion of the mitral valve. Pacing was indicated for sinus node dysfunction. AV sequential pacing with a short optimal AV interval of 60 ms demonstrated a 45% reduction in the degree of LVOT obstruction. This article suggests that LVOT obstruction after the Senning procedure can be palliated by asynchronous septal contraction induced by AV sequential pacing, even if the activation is from LV apex, and avoid or postpone surgery in selected situations.
authors.affiliation: Cook Children's Medical Center, Fort Worth, Texas.
authors.forename: K
authors.initials: K
authors.lastname: Avasarala
authors.forename: C
authors.initials: C
authors.lastname: Case
authors.forename: M
authors.initials: M
authors.lastname: Wienecke
authors.forename: V
authors.initials: V
authors.lastname: Zeigler
authors.forename: L
authors.initials: L
authors.lastname: Lai
authors.forename: P
authors.initials: P
authors.lastname: Gillette
mesh_terms: D000293:Adolescent; D000792:Angiography; D001146:Arrhythmia, Sinus / Q000628:therapy; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D004562:Electrocardiography; D006801:Humans; D008297:Male; D010138:Pacemaker, Artificial; D014188:Transposition of Great Vessels / Q000150:complications*; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000628:therapy; D014694:Ventricular Outflow Obstruction / Q000628:therapy*