title: A review of basic science issues in low back pain.
abstract: This review article is based on a workshop, "New Horizons in Low Back Pain" that was held in November 1995 in San Diego, California. The current article follows the 1995 workshop format of a series of three case study models. Three classical clinical profiles were presented for consideration: lumbar radiculopathy, idiopathic (degenerative disk) low back pain, and degenerative stenosis. This article summarizes the basic science perspectives that were presented and discussed on each topic.
authors.affiliation: Osiris Therapeutics, Inc, Baltimore, Maryland, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Gordon
authors.forename: J N
authors.initials: JN
authors.lastname: Weinstein
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D016207:Cytokines / Q000502:physiology; D004195:Disease Models, Animal; D018450:Disease Progression; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000150:complications* / Q000503:physiopathology; D017116:Low Back Pain / Q000209:etiology* / Q000503:physiopathology; D012106:Research; D012307:Risk Factors; D013130:Spinal Stenosis / Q000150:complications* / Q000503:physiopathology
chemical_list: D016207:Cytokines