[Optic glioma in children with type 1 neurofibromatosis].
During the period 1985-95 we treated 5 girls and 13 boys with optic glioma associated with Type 1 neurofibromatosis (median age 3 years, range 2-10 years). 6 were treated with radiotherapy alone, 1 with surgery and radiation therapy and 1 with chemotherapy in order to postpone irradiation to an older age; 1 is being followed with no therapy. All children are alive, 2-10 years from diagnosis (mean follow-up time 5.4 years). 3 had improvement of vision following therapy and in 4 visual ability stabilized, including the child being followed without treatment. In 1 vision deteriorated despite therapy.
Ben-Arush
M
M
Goldberg
H
H
Kuten
A
A
Guilbord
J
J
el-Hassid
R
R
D002648:Child; D002675:Child, Preschool; D005910:Glioma / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000235:genetics; D019574:Optic Nerve Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed