Chronic recurrent multifocal osteomyelitis--report of eight patients.
The authors undertook a retrospective review of the clinical records and radiologic findings of eight children with chronic, recurrent multifocal osteomyelitis (CRMO). This disease is a recognized clinicopathologic entity with typical radiographic findings, mostly in the metaphyses of the long bones. The diagnosis is one of exclusion without pathognomonic findings. The patients were treated with non-steroidal anti-inflammatory drugs. There was no evidence of altered bone growth or abnormal joint development. It is concluded that CRMO is a distinct clinical entity that is different from acute or subacute bacterial osteomyelitis. Recognition of this condition is important to avoid treatment with antibiotics and repeated operations.
Handrick
W
W
Department of Paediatrics, University Hospital, Oststrasse 21-25, D-04317 Leipzig, Germany.
Hörmann
D
D
Voppmann
A
A
Schille
R
R
Reichardt
P
P
Tröbs
R B
RB
Möritz
R P
RP
Borte
M
M
D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D011859:Radiography; D012008:Recurrence; D012189:Retrospective Studies
D000894:Anti-Inflammatory Agents, Non-Steroidal