title: Pharmacologic adjuncts to mechanical ventilation in acute respiratory distress syndrome.
abstract: This article reviews pharmacologic approaches to treating acute respiratory distress syndrome (ARDS). The authors discuss the therapeutic effects of ketoconazole, antioxidants, corticosteroids, surfactant, ketanserin, pentoxifylline, bronchodilators, and almitrine in ARDS. Current animal data and proposed mechanics which may foster future pharmacologic therapies are also examined.
authors.affiliation: Department of Internal Medicine, University of California, Davis, School of Medicine, Sacramento, USA.
authors.forename: T E
authors.initials: TE
authors.lastname: Albertson
authors.forename: G P
authors.initials: GP
authors.lastname: Marelich
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000975:Antioxidants / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant / Q000379:methods; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D012121:Respiration, Artificial; D012128:Respiratory Distress Syndrome / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D019141:Respiratory System Agents / Q000627:therapeutic use*; D013256:Steroids
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D019141:Respiratory System Agents; D013256:Steroids