Adaptation of hearts to chronic hypoxia increases tolerance to subsequent ischemia by increased nitric oxide production.
Baker
J E
JE
Department of Cardiothoracic Surgery, Medical College of Wisconsin 53226, USA.
Holman
P
P
Kalyanaraman
B
B
Pritchard
K A
KA
D000375:Aging; D000818:Animals; D006152:Cyclic GMP / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D015971:Gene Expression Regulation, Enzymologic; D006321:Heart / Q000502:physiology / Q000503:physiopathology*; D000860:Hypoxia / Q000503:physiopathology*; D066298:In Vitro Techniques; D017202:Myocardial Ischemia / Q000503:physiopathology*; D015425:Myocardial Reperfusion; D009206:Myocardium / Q000378:metabolism*; D009566:Nitrates / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism*; D019001:Nitric Oxide Synthase / Q000235:genetics* / Q000378:metabolism; D009573:Nitrites / Q000378:metabolism; D011817:Rabbits; D012772:Shock, Septic / Q000378:metabolism / Q000503:physiopathology*; D013312:Stress, Physiological / Q000503:physiopathology; D014158:Transcription, Genetic; D016277:Ventricular Function, Left / Q000502:physiology; D016278:Ventricular Function, Right / Q000502:physiology
D009566:Nitrates; D009573:Nitrites; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D006152:Cyclic GMP