Neutral polysaccharide from Cedrela tubiflora with anticomplementary activity.
A water-soluble polysaccharide extracted from leaves of the Meliaceae Cedrela tubiflora was separated into neutral and acidic polysaccharide fractions. The best anticomplementary activity was exhibited by the neutral product which was further purified by means of gelpermeation chromatography. The composition and methylation analysis of the purified product were determined.
Benencia
F
F
Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Pabellón 2, Ciudad Universitaria, Buenos Aires, Argentina.
Rodriguez
M C
MC
Matulewicz
M C
MC
Coulombié
F C
FC
D000818:Animals; D002241:Carbohydrates / Q000032:analysis; D002850:Chromatography, Gel; D003170:Complement Pathway, Alternative / Q000187:drug effects*; D003171:Complement Pathway, Classical / Q000187:drug effects*; D004912:Erythrocytes / Q000187:drug effects / Q000502:physiology; D006462:Hemolytic Plaque Technique; D006801:Humans; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal; D011134:Polysaccharides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D011817:Rabbits
D002241:Carbohydrates; D011134:Polysaccharides