title: Simplified hepatic resection utilizing absorbable polyglycolic acid-based tape and other ligature apparatus.
abstract: Hepatic resection has been increasing in frequency in the management of metastatic or primary neoplasms of the liver. Although mortality for this procedure has steadily decreased, the associated morbidity remains high. Morbidity is mainly associated with operative time and blood loss, especially in jaundiced and cirrhotic patients. During hepatic resection, control of bleeding from various sources is the most important problem faced by surgeons. During conventional lobectomy, despite prior control of hepatic artery and portal vein to that lobe, bleeding still occurs from the opposite lobe or back flow from hepatic veins. We usually apply Pringle's maneuver for hemostasis, but consequently there is postoperative hepatic dysfunction. We have previously investigated methods for vascular occlusion at the site of liver resection. We developed a new absorbable polyglycolic acid-based tape (breadth, 3 mm; length, 70 cm) for use in hepatic mass ligation, as well as two types of ligature apparatus. Hemostasis was achieved with these devices, and all lobar, segmental, and non-anatomic resections were performed without prior control of the portal venous system, hepatic arterial inflow, and hepatic venous outflow before parenchymal resection. This significantly shortened the operative time, as well as decreasing the blood loss during hepatic resection, with consequent reduction of postoperative morbidity. The use of this absorbable tape may reduce the incidence of local infection, abscess formation, and septicemia.
authors.affiliation: First Department of Surgery, Tohoku University School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
authors.forename: K
authors.initials: K
authors.lastname: Fukuhara
authors.forename: M
authors.initials: M
authors.lastname: Unno
authors.forename: T
authors.initials: T
authors.lastname: Rikiyama
authors.forename: H
authors.initials: H
authors.lastname: Takeuchi
authors.forename: T
authors.initials: T
authors.lastname: Uchiyama
authors.forename: S
authors.initials: S
authors.lastname: Matsuno
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D006488:Hemostasis, Surgical / Q000295:instrumentation* / Q000379:methods*; D006498:Hepatectomy / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008026:Ligation / Q000295:instrumentation; D008107:Liver Diseases / Q000601:surgery; D008113:Liver Neoplasms / Q000601:surgery; D011100:Polyglycolic Acid; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D011100:Polyglycolic Acid