Synthesis and reactivities of 3-indocyanine-green-acyl-1,3-thiazolidine-2-thione (ICG-ATT) as a new near-infrared fluorescent-labeling reagent.
A new near-infrared fluorescent-labeling reagent (ICG-ATT) bearing the 3-acyl-1,3-thiazolidine-2-thione (ATT) moiety with the chemoselective acylation feature and the dye moiety of indocyanine green (ICG) has been developed. Synthesis and reactivities of the ICG-ATT are described.
Hirata
T
T
Faculty of Pharmaceutical Sciences, University of Tokushima, Japan.
Kogiso
H
H
Morimoto
K
K
Miyamoto
S
S
Taue
H
H
Sano
S
S
Muguruma
N
N
Ito
S
S
Nagao
Y
Y
D000215:Acylation; D000818:Animals; D002417:Cattle; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D007074:Immunoglobulin G; D007202:Indicators and Reagents; D007208:Indocyanine Green / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D012710:Serum Albumin, Bovine; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D013844:Thiazoles; D053778:Thiazolidines; D013871:Thiones
C116779:3-indocyanine-green-acyl-1,3-thiazolidine-2-thione; D005456:Fluorescent Dyes; D007074:Immunoglobulin G; D007202:Indicators and Reagents; D013844:Thiazoles; D053778:Thiazolidines; D013871:Thiones; D012710:Serum Albumin, Bovine; D007208:Indocyanine Green