[Early detection and control of risk factors in diabetic nephropathy].
Diabetic nephropathy is an important complication of diabetes. Established nephropathy is preceded by a long silent phase of incipient nephropathy characterized by a subclinical increase in albumin excretion know as microalbuminuria (30-300 mg/d). There is evidence that the progression of nephropathy and its associated mortality can be ameliorated by a number of interventions if started at a nearly stage: glycaemic control, that should be optimized as far as possible, and hypertension control. Angiotensin-converting enzyme (ACE) inhibitors are promoted as first-line agent for treating hypertension in diabetic patients; as well as their systemic hypotensive action, these drugs may have an additional beneficial effect in reducing intraglomerular pressure.
Fernández López
M T
MT
Servicio de Endocrinología, Hospital Juan Canalejo, La Coruña.
Isidro San Juan
M L
ML
Cordido
F
F
D000419:Albuminuria / Q000209:etiology; D001786:Blood Glucose; D003928:Diabetic Nephropathies / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D004044:Dietary Proteins / Q000008:administration & dosage; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy; D012307:Risk Factors
D001786:Blood Glucose; D004044:Dietary Proteins