Mesothelial cell proliferation in the scala tympani: a reaction to the rupture of the round window membrane.
The inner layer of the round window membrane is composed of mesothelial cells and this mesothelial cell layer extends to the scala tympani. This study describes the histopathologic findings of temporal bone analysis from a patient with bilateral perilymphatic fistula of the round window membrane. The left ear showed proliferation of mesothelial cells in the scala tympani of the basal turn adjoining the round window membrane. This cell proliferation is thought to be a reaction to the rupture of the round window membrane.
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Department of Otorhinolaryngology, Nagoya University School of Medicine, Japan.
D002455:Cell Division; D015834:Cochlear Diseases / Q000473:pathology*; D004847:Epithelial Cells / Q000502:physiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012405:Round Window, Ear / Q000473:pathology*; D012422:Rupture, Spontaneous; D012533:Scala Tympani / Q000473:pathology*