title: [Results of organ-preserving and reconstructive surgery of the mandible in patients with cancer of the oral cavity].
abstract: Surgery is the basic procedure of combined therapy for locally-advanced carcinoma of the oral mucosa. It is intended to excise involved mucosa and soft tissues of the oral cavity and to resect the mandible. Rim resection (55) produces good functional and cosmetic results and was followed by 5-year survival in 76.4%. Due to median mandibulotomy (24), optimal access was provided to tumor involving the whole tongue and sitting at the back of the oral cavity (5-year survival--58.3%). Postoperative complication incidence was significantly lowered when titanium miniplates were used for mandibular arch reconstruction. When these miniplates and osteomyocutaneous flaps were used for mandibular reconstruction, following segmental resection, good cosmetic and functional results were recorded in 5 out of 8 cases (5-year survival--75%).
authors.affiliation: N.N. Blokhin Center for Cancer Research, Russian Academy of Medical Sciences, Moscow.
authors.forename: E G
authors.initials: EG
authors.lastname: Matiakin
authors.forename: A A
authors.initials: AA
authors.lastname: Uvarov
authors.forename: M A
authors.initials: MA
authors.lastname: Kropotov
authors.forename: R I
authors.initials: RI
authors.lastname: Azizian
mesh_terms: D000328:Adult; D000539:Alveolar Process / Q000473:pathology; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D008339:Mandibular Neoplasms / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D011879:Radiotherapy Dosage; D013518:Surgery, Plastic; D013524:Surgical Flaps; D014062:Tongue Neoplasms / Q000473:pathology / Q000601:surgery
chemical_list: D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil