title: Venlafaxine-tramadol similarities.
abstract: Venlafaxine and tramadol are relatively new compounds indicated for the treatment of depression and pain, respectively. These agents share a number of molecular and pharmacological features that may allow for broader and overlapping therapeutic indications for both drugs. Additionally, certain patient populations with coexisting depression and pain syndromes could potentially be treated with a single agent.
authors.affiliation: Department of Pharmacy Practice, Institute of Psychiatry, Medical University of South Carolina, Charleston 29425-0810, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Markowitz
authors.forename: K S
authors.initials: KS
authors.lastname: Patrick
mesh_terms: D000701:Analgesics, Opioid / Q000737:chemistry / Q000627:therapeutic use*; D018687:Antidepressive Agents, Second-Generation / Q000737:chemistry / Q000627:therapeutic use*; D003511:Cyclohexanols / Q000737:chemistry / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D008954:Models, Biological; D008960:Models, Psychological; D015394:Molecular Structure; D010146:Pain / Q000188:drug therapy*; D013329:Structure-Activity Relationship; D014147:Tramadol / Q000737:chemistry / Q000627:therapeutic use*; D000069470:Venlafaxine Hydrochloride
chemical_list: D000701:Analgesics, Opioid; D018687:Antidepressive Agents, Second-Generation; D003511:Cyclohexanols; D014147:Tramadol; D000069470:Venlafaxine Hydrochloride