Carbohydrate sulfotransferases: mediators of extracellular communication.
Sulfated carbohydrates mediate diverse extracellular recognition events in both normal and pathological processes. The sulfotransferases that generate specific carbohydrate 'sulfoforms' have recently been recognized as key modulators of these processes and therefore represent potential therapeutic targets.
Bowman
K G
KG
Department of Chemistry, University of California, Berkeley 94720, USA.
Bertozzi
C R
CR
D000818:Animals; D001692:Biological Transport; D050260:Carbohydrate Metabolism; D002240:Carbohydrate Sequence; D002241:Carbohydrates / Q000502:physiology*; D002450:Cell Communication; D005965:Glucuronates / Q000378:metabolism; D020723:Glucuronic Acid; D006023:Glycoproteins / Q000378:metabolism; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D011134:Polysaccharides / Q000378:metabolism; D012231:Rhizobium / Q000201:enzymology; D015238:Sulfotransferases / Q000378:metabolism / Q000502:physiology*
D002241:Carbohydrates; D005965:Glucuronates; D006023:Glycoproteins; D011134:Polysaccharides; D020723:Glucuronic Acid; D015238:Sulfotransferases