title: Sensitive median-ulnar motor comparative techniques in carpal tunnel syndrome.
abstract: We describe two modified methods for median-to-ulnar motor conduction comparison in the diagnosis of median neuropathy at the wrist: the median-thenar to ulnar-thenar latency difference (TTLD), and the median-thenar to ulnar-hypothenar latency difference (THLD). We also describe an F-wave ulnar-to-median comparative test, the F-wave latency difference (FWLD). The abnormal cutoffs based upon 34 normal controls are: TTLD, 0.8 ms; THLD, 1.2 ms; FWLD, 0.6 ms. In 50 patients (79 hands) with clinically defined carpal tunnel syndrome and electrophysiological evidence of median neuropathy at the wrist (based upon a prolonged median nerve palm-wrist latency), the diagnostic sensitivities were: 95-98%, 85-88%, and 75-78%, respectively. These tests are therefore highly sensitive. They are easily performed and require minimal additional effort to incorporate into commonly used clinical electrodiagnostic routines. They may be advantageous when a concomitant polyneuropathy is present, and they may also help avoid technical pitfalls and aid in identification of anatomic variants.
authors.affiliation: Department of Neurology, St. Vincent's Hospital of New York, New York 10011, USA.
authors.forename: H W
authors.initials: HW
authors.lastname: Sander
authors.forename: C
authors.initials: C
authors.lastname: Quinto
authors.forename: P B
authors.initials: PB
authors.lastname: Saadeh
authors.forename: S
authors.initials: S
authors.lastname: Chokroverty
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000328:Adult; D000368:Aged; D002349:Carpal Tunnel Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D004576:Electromyography / Q000379:methods*; D006801:Humans; D008475:Median Nerve / Q000502:physiology*; D008875:Middle Aged; D011446:Prospective Studies; D011930:Reaction Time / Q000502:physiology; D012680:Sensitivity and Specificity; D004561:Transcutaneous Electric Nerve Stimulation; D014459:Ulnar Nerve / Q000502:physiology*; D014953:Wrist / Q000294:innervation