[Effects of cystamine on the state of peripheral blood neutrophilic granulocytes in vivo in rats].
It has been found experimentally, that decay of the intercellular energy exchange, intensification of the secretory degranulation, activation of the oxygen-dependent enzyme system and increasing the functional potential of the male-rats neutrophils took place on the height of the protective action of cystamine. On the 1-st day the tendency to restoration was noted and the normalisation of the functional and metabolical status of the neutrophils could be seen on the 5-th day after injection.
Grebeniuk
A N
AN
Military Medical Academy, St.-Petersburg.
Smirnov
N A
NA
D000818:Animals; D003538:Cystamine / Q000008:administration & dosage / Q000494:pharmacology*; D007274:Injections, Intraperitoneal; D008297:Male; D009504:Neutrophils / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D051381:Rats; D012984:Software; D013268:Stimulation, Chemical; D013997:Time Factors; D015054:Zymosan / Q000494:pharmacology
D011837:Radiation-Protective Agents; D015054:Zymosan; D003538:Cystamine