An event-related potential study of age-related changes in sensitivity to stimulus deviance.
The mismatch negativity (MMN) of the event-related (brain) potential (ERP) has been shown to reflect the storage of information in sensory memory and is thought to reflect the operation of a mechanism that compares frequently occurring standard with infrequently occurring deviant acoustic events. The MMN was recorded from young (mean = 23 years) and elderly (mean = 72 years) adults to small (50 Hz) and large (300 Hz) frequency deviants and to a variety of novel, environmental sounds. At each level of deviance, MMN amplitude was smaller in the ERPs of older relative to younger adults. Young, but not older adults showed robust MMNs at the smallest level of deviance. Moreover, a P3 component was observed in the ERPs of the young to both large tonal and novel deviants, whereas a robust P3 component was evident only to the novel deviants in the ERPs of the old. The data suggest that older adults demonstrate less sensitivity to stimulus deviance and that only highly deviant events are likely to involuntarily capture their attention.
Gaeta
H
H
Cognitive Electrophysiology Laboratory, New York State Psychiatric Institute, New York 10032, USA. gaetahe@pi.cpmc.columbia.edu
Friedman
D
D
Ritter
W
W
Cheng
J
J
D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D001931:Brain Mapping; D003265:Contingent Negative Variation / Q000502:physiology*; D004193:Discrimination Learning / Q000502:physiology; D004569:Electroencephalography; D006801:Humans; D008568:Memory / Q000502:physiology; D009040:Motion Pictures; D009475:Neurons, Afferent / Q000502:physiology*; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology; D014793:Visual Cortex / Q000502:physiology