Hyalinizing clear cell carcinoma of the oral cavity and of the parotid gland.
Hyalinizing clear cell carcinoma (HCCC) is a rare, recently described tumor of salivary gland origin. Differential diagnosis includes benign lesions as clear cell change in a pleomorphic adenoma or in oncocytoma and malignant tumors - i.e. epithelial-myoepithelial carcinoma, polymorphous low-grade adenocarcinoma, mucoepidermoid carcinoma, clear cell acinic carcinoma, clear cell squamous carcinoma, clear cell malignant melanoma, clear cell odontogenic carcinoma, clear cell rhabdomyosarcoma, sebaceous carcinoma and metastasis of renal carcinoma. A favorable prognosis after wide local excision has been evidenced. Three new cases of HCCC (2 in the oral cavity and 1 in the parotid gland) are presented.
Rinaldo
A
A
Department of Otolaryngology, City Hospital, Royal Infirmary of Edinburgh, UK.
McLaren
K M
KM
Boccato
P
P
Maran
A G
AG
D000230:Adenocarcinoma / Q000175:diagnosis; D018262:Adenocarcinoma, Clear Cell / Q000175:diagnosis* / Q000473:pathology; D018266:Adenocarcinoma, Sebaceous / Q000175:diagnosis; D018249:Adenoma, Oxyphilic / Q000175:diagnosis; D008949:Adenoma, Pleomorphic / Q000175:diagnosis; D000328:Adult; D002277:Carcinoma / Q000175:diagnosis; D018267:Carcinoma, Acinar Cell / Q000175:diagnosis; D018277:Carcinoma, Mucoepidermoid / Q000175:diagnosis; D002292:Carcinoma, Renal Cell / Q000556:secondary; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006818:Hyalin; D008545:Melanoma / Q000175:diagnosis; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000473:pathology; D009808:Odontogenic Tumors / Q000175:diagnosis; D010307:Parotid Neoplasms / Q000175:diagnosis* / Q000473:pathology; D011379:Prognosis; D012208:Rhabdomyosarcoma / Q000175:diagnosis