title: Lyme disease associated with unilateral interstitial keratitis.
abstract: OBJECTIVE
  To report a case of Lyme disease that presented with a single nummular unilateral interstitial keratitis.
  
  
  METHODS
  Case report and review of the literature.
  
  
  RESULTS
  A 57-year-old black man who had contact with freshly killed deer had a chief complaint of foreign-body sensation in his right eye (OD) that had been diagnosed and treated for herpes simplex stromal keratitis. The patient underwent a systemic workup for interstitial keratitis. All results including RPR and MHA-TP were negative except for Lyme antibody titer (enzyme-linked immunosorbent assay [ELISA]) 178 U/ml (normal, <159 U/ml).
  
  
  CONCLUSIONS
  Interstitial keratitis from Lyme disease has been regarded as a bilateral disease in the literature. We present this infrequent ocular manifestation of Lyme disease as a rare single nummular unilateral presentation.
authors.affiliation: Department of Ophthalmology and Visual Science, The University of Texas Medical School at Houston, 77030, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Miyashiro
authors.forename: R W
authors.initials: RW
authors.lastname: Yee
authors.forename: G
authors.initials: G
authors.lastname: Patel
authors.forename: R S
authors.initials: RS
authors.lastname: Ruiz
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000032:analysis; D015748:Borrelia burgdorferi Group / Q000276:immunology; D003319:Corneal Stroma / Q000382:microbiology; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005500:Follow-Up Studies; D006801:Humans; D007634:Keratitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D008193:Lyme Disease / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D013752:Tetracycline / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D013752:Tetracycline