title: [Continuous injection therapy of morphine solution for terminally-ill patients at home].
abstract: We surveyed 21 terminally-ill patients with cancer pain who received continuous injection therapy of morphine at home in the three years from 1995 to 1997. The period of home therapy was 179.3 +/- 257.5 (mean +/- SD) days. The period of morphine injection was 39.2 +/- 29.1 days. Morphine solution was injected intravenously via a catheter inserted in a central vein in all patients. The instrument used most frequently for injection was the seven-day type disposable balloon pump (n = 17, 81.0%). The maximum dosage of morphine in the period of home therapy was 57.3 +/- 30.6 mg per day. Nine patients (42.9%) seldom used supplemental analgesics, while 11 patients (52.4%) used them sometimes. Nine patients had some trouble with continuous injection therapy of morphine. The following were problems: accidents with the injection instruments (insufficient injection volume, delay of drug supply, etc.) and of the intravenous catheters (accidental removal of catheter, occlusion of catheter, etc.). Eleven patients (52.4%) died at home, and 10 patients (47.6%) were hospitalized again. Continuous morphine injection therapy is an effective strategy for cancer pain management at home.
authors.affiliation: Terminal Care Study Group, Hiraka General Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Matsumoto
authors.forename: H
authors.initials: H
authors.lastname: Terashima
authors.forename: H
authors.initials: H
authors.lastname: Komatsu
authors.forename: K
authors.initials: K
authors.lastname: Abe
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage*; D002405:Catheterization, Central Venous / Q000379:methods*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage*; D009369:Neoplasms / Q000503:physiopathology; D010146:Pain / Q000188:drug therapy*; D019452:Terminally Ill
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine