Intracavernous methoxamine in the treatment of priapism.
Methoxamine is an alpha-adrenergic drug, its unique pharmacokinetics and mechanism of action on alpha-1 receptors lead to consider it, similarly to phenylephrine, as a first-choice drug for treating drug-induced or veno-occlusive priapism. The experience obtained with its use in the management of three cases of priapism lasting over 7 h and one case of sustained rigid erection caused during anesthetic induction are reported.
Jara
J
J
Urology Department, Hospital General Universitario, Madrid, Spain.
Moncada
I
I
Bueno
G
G
Hernandez
C
C
D000316:Adrenergic alpha-Agonists / Q000627:therapeutic use; D000328:Adult; D006801:Humans; D008297:Male; D008729:Methoxamine / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D010413:Penis / Q000187:drug effects*; D011317:Priapism / Q000139:chemically induced / Q000188:drug therapy*; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000009:adverse effects
D000316:Adrenergic alpha-Agonists; D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents; D008729:Methoxamine