title: [Diagnostic value of 10 systematized and ultrasound-guided transrectal prostatic biopsies].
abstract: OBJECTIVE
  To study the improvement of prostatic cancer detection provided by ten strictly systematized transrectal prostatic biopsies.
  
  
  METHODS
  This prospective study was conducted in 162 patients submitted to a series of 10 ultrasound-guided transrectal prostatic biopsies due to the presence of elevated PSA and/or an abnormality on digital rectal examination. Five biopsies were taken from different sites in each lobe: 2 biopsies were inserted between the 3 biopsies usually performed in the standard protocol, while maintaining the angle of entry of the needle recommended in this protocol.
  
  
  RESULTS
  The complication rate was 1.85% with the 10-biopsy technique. Prostatic cancer was detected in 40.1% of the 162 patients. The percentage diagnostic improvement provided by the 10-biopsy protocol in the overall patient population was +3.1% compared to the standard protocol. The highest percentage diagnostic improvement was observed in the group of patients with PSA < or = 10 ng/ml (+4.9%) and in the group of patients with an ultrasound prostatic volume < or = 40 cc (+4%).
  
  
  CONCLUSIONS
  The most marked diagnostic improvement appears to be related more to sampling of prostatic zones presenting a statistically increased risk of cancer (peripheral zone) than to the increased number of prostatic biopsies performed.
authors.affiliation: Service d'Urologie, Hôpital Bichat, Paris, France.
authors.forename: V
authors.initials: V
authors.lastname: Ravery
authors.forename: T
authors.initials: T
authors.lastname: Billebaud
authors.forename: M
authors.initials: M
authors.lastname: Toublanc
authors.forename: L
authors.initials: L
authors.lastname: Boccon-Gibod
authors.forename: J F
authors.initials: JF
authors.lastname: Hermieu
authors.forename: F
authors.initials: F
authors.lastname: Moulinier
authors.forename: E
authors.initials: E
authors.lastname: Blanc
authors.forename: V
authors.initials: V
authors.lastname: Delmas
authors.forename: L
authors.initials: L
authors.lastname: Boccon-Gibod
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy / Q000379:methods*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011467:Prostate / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000097:blood; D011470:Prostatic Hyperplasia / Q000175:diagnosis* / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D014463:Ultrasonography
chemical_list: D017430:Prostate-Specific Antigen