Noninfectious lung disease in immunocompromised patients.
Immunocompromised hosts have defects in their immune system that make them at risk of developing a variety of infections. In addition, these persons may develop a wide variety of noninfectious disease processes that involve the lung. These disorders may be caused by the underlying disease process. This may be seen with the development of metastatic disease from the underlying neoplasm, or it may represent the development of a malignancy secondary to therapy, as is seen with posttransplant lymphoproliferative disease. The abnormalities may be a result of the therapy used to treat the patients, as is seen with radiation injury to the lung and drug toxicity. Pulmonary edema may occur and be from a wide variety of causes. All of these disease processes may simulate an infectious process and must be differentiated from infection to allow proper therapeutic intervention.
Conces
D J
DJ
Department of Radiology, Indiana University School of Medicine, Indianapolis, USA.
D017088:AIDS-Related Opportunistic Infections / Q000209:etiology; D003937:Diagnosis, Differential; D006801:Humans; D016867:Immunocompromised Host; D008168:Lung / Q000187:drug effects / Q000528:radiation effects; D008171:Lung Diseases / Q000139:chemically induced / Q000209:etiology* / Q000382:microbiology; D008175:Lung Neoplasms / Q000556:secondary; D008232:Lymphoproliferative Disorders / Q000209:etiology; D016609:Neoplasms, Second Primary / Q000209:etiology; D016377:Organ Transplantation / Q000009:adverse effects; D011654:Pulmonary Edema / Q000209:etiology; D017564:Radiation Pneumonitis / Q000209:etiology; D012307:Risk Factors