MALT lymphomas in 1997. Where do we stand?
Steady advances in our scientific understanding of primary extranodal mucosa-associated lymphoid tissue-type lymphomas have been achieved during the past 14 years, leading to their inclusion within the International Lymphoma Study Group (revised European-American classification of lymphoid neoplasms, known as REAL) classification as extranodal B-marginal zone lymphomas. Although most cases conform to prototype criteria, exceptional cases, such as those discussed at the Fourth Slide Workshop of the Society for Hematopathology on Extranodal Hematopoietic/Lymphoid Disorders, September 11-13, 1997, raise issues relating to microscopic, immunophenotypic, and clinical behavioral limits for diagnostic criteria. Furthermore, questions about therapeutic management have only begun to be addressed.
Banks
P M
PM
Department of Pathology, Carolinas Medical Center, Charlotte, North Carolina 28232-2861, USA.
Isaacson
P G
PG
D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000145:classification* / Q000473:pathology*