Signet ring breast carcinoma metastases limited to the endometrium and cervix.
Breast cancer metastatic to the cervix and uterus in the absence of extrapelvic foci is a rare finding in the medical literature. Signet ring breast carcinoma is also an unusual neoplasm. We present an asymptomatic 71-year-old woman 2 years status-post modified radical mastectomy for signet ring carcinoma who was found to have metastatic lesions to the cervix and endometrium at the time of a routine gynecological examination. Bone scan as well as computerized tomography of the chest, abdomen, and pelvis failed to locate other metastatic sites. We believe this to be the only reported case of signet ring breast carcinoma metastatic solely to the uterus and cervix. The patient's lack of recent pelvic examination highlights the need for continued gynecological evaluation in patients with breast cancer.
Kennebeck
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CH
Department of Obstetrics and Gynecology, David Grant Medical Center, Travis Air Force Base, California, 94535-1800, USA.
Alagoz
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D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology*; D018279:Carcinoma, Signet Ring Cell / Q000556:secondary*; D016889:Endometrial Neoplasms / Q000556:secondary*; D005260:Female; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000556:secondary*