title: Protein engineering on enzymes of the peptide elongation cycle in Sulfolobus solfataricus.
abstract: The present article is a review of the work done on the elongation factors EF-1 alpha, EF-2 and EF-1 beta isolated from the hyperthermophilic archaeon Sulfolobus solfataricus. The molecular, physical and biochemical properties of the intact, truncated, mutant or chimeric forms are described and compared.
authors.affiliation: Dipartimento di Biochimica e Biotecnologie Mediche, Università di Napoli Federico II, Naples, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Bocchini
authors.forename: B S
authors.initials: BS
authors.lastname: Adinolfi
authors.forename: P
authors.initials: P
authors.lastname: Arcari
authors.forename: A
authors.initials: A
authors.lastname: Arcucci
authors.forename: A
authors.initials: A
authors.lastname: Dello Russo
authors.forename: E
authors.initials: E
authors.lastname: De Vendittis
authors.forename: G
authors.initials: G
authors.lastname: Ianniciello
authors.forename: M
authors.initials: M
authors.lastname: Masullo
authors.forename: G
authors.initials: G
authors.lastname: Raimo
mesh_terms: D004926:Escherichia coli / Q000737:chemistry; D007700:Kinetics; D009154:Mutation; D020648:Peptide Elongation Factor 1; D020652:Peptide Elongation Factor 2; D010444:Peptide Elongation Factor Tu / Q000737:chemistry; D010445:Peptide Elongation Factors / Q000737:chemistry* / Q000235:genetics; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D013329:Structure-Activity Relationship; D016944:Sulfolobus / Q000737:chemistry* / Q000201:enzymology
chemical_list: D020648:Peptide Elongation Factor 1; D020652:Peptide Elongation Factor 2; D010445:Peptide Elongation Factors; D011993:Recombinant Fusion Proteins; D010444:Peptide Elongation Factor Tu