Anencephaly-associated aganglionosis.
Autopsies of 12 consecutively born infants with anencephaly showed varying degrees of aganglionosis and lateralization defects in four of them. This seemingly regular occurrence of these three defects together suggests that they are caused by an aberration of blastogenesis that results in a polytopic field defect.
Mathew
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J.J.M. Medical College, Davengere, Karnataka, India.
D000757:Anencephaly / Q000150:complications*; D005260:Female; D006627:Hirschsprung Disease / Q000150:complications*; D006801:Humans; D009436:Neural Tube Defects / Q000150:complications; D006831:Polyhydramnios / Q000150:complications; D011247:Pregnancy; D013368:Submucous Plexus / Q000002:abnormalities