title: Localized hypertrophic neuropathy: magnetic resonance imaging findings and long-term follow-up.
abstract: Four patients with painless, progressive focal neurological deficits that localized to peripheral nerve or plexus were eventually found to have the relatively rare condition of localized hypertrophic neuropathy or intraneural perineurioma. Magnetic resonance imaging (MRI) was an excellent tool for aiding in the precise localization of the lesion, if specifically tailored with regard to imaging planes and specific MRI sequences. Fat-saturated T2-weighted and fat-saturated T1-weighted postgadolinium images provided the best visualization, particularly with a high-field magnet and phase array body coil. Two patients stabilized following resection of the lesion and sural nerve grafting, and 1 had partial improvement in a proximal muscle following neurolysis.
authors.affiliation: Division of Neurology, Penn State College of Medicine, Hershey Medical Center, Pennsylvania 17033, USA.
authors.forename: Z
authors.initials: Z
authors.lastname: Simmons
authors.forename: Z I
authors.initials: ZI
authors.lastname: Mahadeen
authors.forename: M J
authors.initials: MJ
authors.lastname: Kothari
authors.forename: S
authors.initials: S
authors.lastname: Powers
authors.forename: S
authors.initials: S
authors.lastname: Wise
authors.forename: J
authors.initials: J
authors.lastname: Towfighi
mesh_terms: D000293:Adolescent; D000328:Adult; D001132:Arm / Q000294:innervation; D001917:Brachial Plexus / Q000473:pathology; D002648:Child; D005260:Female; D005267:Femoral Nerve / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D006984:Hypertrophy; D007866:Leg / Q000294:innervation; D008279:Magnetic Resonance Imaging; D008297:Male; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis* / Q000473:pathology; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012584:Sciatic Nerve / Q000473:pathology