title: Identification of SycN, YscX, and YscY, three new elements of the Yersinia yop virulon.
abstract: The Yop virulon allows Yersinia spp. to resist the immune response of the host by injecting harmful proteins into host cells. We identified three new elements of the Yop virulon: SycN, required for normal secretion of YopN, and YscX and YscY, two new components of the secretion machinery.
authors.affiliation: Microbial Pathogenesis Unit, Christian de Duve Institute of Cellular Pathology and Faculté de Médecine, Université Catholique de Louvain, B-1200 Brussels, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Iriarte
authors.forename: G R
authors.initials: GR
authors.lastname: Cornelis
mesh_terms: D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000235:genetics*; D005838:Genotype; D008565:Membrane Proteins; D018832:Molecular Chaperones / Q000096:biosynthesis / Q000235:genetics*; D016297:Mutagenesis, Site-Directed; D010957:Plasmids; D011994:Recombinant Proteins / Q000096:biosynthesis; D015183:Restriction Mapping; D014774:Virulence / Q000235:genetics; D015007:Yersinia / Q000235:genetics* / Q000472:pathogenicity*
chemical_list: D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D008565:Membrane Proteins; D018832:Molecular Chaperones; D011994:Recombinant Proteins; C070015:YopN protein, Yersinia