title: Fibromuscular dysplasia of the renal arteries: comparison of helical CT angiography and arteriography.
abstract: OBJECTIVE
  We evaluated the role of helical CT angiography rendering techniques in the assessment of renal artery fibromuscular dysplasia.
  
  
  METHODS
  Twenty hypertensive patients (mean age, 56 years) with angiographically proven renal artery fibromuscular dysplasia were studied by CT angiography. The acquisition protocol was collimation, 3 mm; table speed, 3 mm/sec; and incremental algorithm, one. Maximum-intensity-projection and shaded-surface-display reconstructions and transverse sections were reviewed by a consensus panel to determine the sensitivity and specificity of each technique in revealing renal artery fibromuscular dysplasia.
  
  
  RESULTS
  Helical CT angiography enabled successful diagnosis of fibromuscular dysplasia in all 20 patients. Helical CT angiography showed 31 of 34 pathologic arteries and 33 of 38 lesions. Aneurysms (>6 mm) on arteriography (n = 12) were revealed in 83% of transverse sections, 75% of maximum-intensity-projection reconstructions, and 58% of shaded-surface-display reconstructions. Lesions that had a string of pearls appearance on arteriography (n = 19) were shown in 53% of transverse sections, 84% of maximum-intensity-projection reconstructions (p < .05 compared with transverse sections), and 74% of shaded-surface-display reconstructions. Stenoses (n = 7 on arteriography) were revealed in 57% of transverse sections, 71% of maximum-intensity-projection reconstructions, and 57% of shaded-surface-display reconstructions. Maximum intensity projection alone revealed 30 (79%) of the 38 angiographic lesions; however, using both maximum intensity projections and transverse sections increased the sensitivity to 87%.
  
  
  CONCLUSIONS
  Helical CT angiography, especially the combination of transverse sections and maximum-intensity-projection reconstructions, can reliably reveal renal artery fibromuscular dysplasia. However, because some lesions may not be shown, arteriography with pressure measurements remains the only technique that can assess the physiologic significance of the dysplasia.
authors.affiliation: Department of Vascular Radiology, Hôpital Cardiologique, Le Centre Hospitalier Régional et Universitaire de Lille, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Beregi
authors.forename: S
authors.initials: S
authors.lastname: Louvegny
authors.forename: C
authors.initials: C
authors.lastname: Gautier
authors.forename: C
authors.initials: C
authors.lastname: Mounier-Vehier
authors.forename: A
authors.initials: A
authors.lastname: Moretti
authors.forename: F
authors.initials: F
authors.lastname: Desmoucelle
authors.forename: L
authors.initials: L
authors.lastname: Wattinne
authors.forename: E
authors.initials: E
authors.lastname: McFadden
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D005260:Female; D005352:Fibromuscular Dysplasia / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D012077:Renal Artery / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed