title: Ultrasound-guided biopsy of abdominal and pelvic lesions in children. A comparison between fine-needle aspiration and 1.2 mm-needle core biopsy.
abstract: BACKGROUND
  Tissue diagnosis is mandatory prior to treatment of an abdominal or pelvic lesion in a child.
  
  
  OBJECTIVE
  To compare the diagnostic yield and complications of fine-needle aspiration biopsy (FNAB) and 1.2-mm needle core biopsy (NCB) for abdominal and pelvic lesions in children using US guidance.
  
  
  METHODS
  Ninety consecutive abdominal or pelvic US-guided biopsies in 61 children; 53 FNAB procedures in 43 children and 37 NCB procedures in 34 children were retrospectively analysed. Fifty-seven biopsies were performed on malignant lesions and 33 on benign lesions. In 15 children, both FNAB and NCB were performed at the same occasion.
  
  
  RESULTS
  FNAB was diagnostic in 41 (77 %) of 53 biopsies while NCB provided a correct diagnosis in 35 (95 %) of 37 biopsies. Results were similar in both malignant and benign conditions. Clinically important bleeding complicated three biopsies (3.3 %); in two after FNAB and in one after combined FNAB and NCB.
  
  
  CONCLUSIONS
  If FNAB were to be replaced with 1.2-mm NCB using an automatic gun, the diagnostic yield for abdominal and pelvic focal lesions in children would improve significantly (P < 0.05) while the complication rate would remain low. NCB may reduce the need for diagnostic and staging surgery and repeated procedures.
authors.affiliation: Department of Radiology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
authors.forename: C O
authors.initials: CO
authors.lastname: Hugosson
authors.forename: R S
authors.initials: RS
authors.lastname: Nyman
authors.forename: J M
authors.initials: JM
authors.lastname: Cappelen-Smith
authors.forename: M
authors.initials: M
authors.lastname: Akhtar
authors.forename: C
authors.initials: C
authors.lastname: Hugosson
mesh_terms: D000008:Abdominal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D000293:Adolescent; D001707:Biopsy, Needle / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010386:Pelvic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014463:Ultrasonography