RSR13, a synthetic allosteric modifier of hemoglobin, enhances recovery of stunned myocardium in dogs.
Pagel
P S
PS
Department of Anesthesiology, Medical College of Wisconsin, Milwaukee 53226, USA.
Hettrick
D A
DA
Montgomery
M W
MW
Kersten
J R
JR
Warltier
D C
DC
D000494:Allosteric Regulation; D000704:Analysis of Variance; D000814:Aniline Compounds / Q000627:therapeutic use*; D000818:Animals; D000986:Antisickling Agents / Q000627:therapeutic use*; D003326:Coronary Circulation / Q000187:drug effects*; D004285:Dogs; D005260:Female; D006321:Heart / Q000187:drug effects; D006439:Hemodynamics; D006454:Hemoglobins / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D017202:Myocardial Ischemia / Q000503:physiopathology; D015425:Myocardial Reperfusion; D017682:Myocardial Stunning / Q000188:drug therapy / Q000503:physiopathology*; D011422:Propionates / Q000627:therapeutic use*; D012039:Regional Blood Flow / Q000187:drug effects
D000814:Aniline Compounds; D000986:Antisickling Agents; D006454:Hemoglobins; D011422:Propionates; C067396:efaproxiral