title: Simulated frame-loss artifacts in myocardial perfusion SPECT imaging: the difference between single- and dual-headed systems.
abstract: OBJECTIVE
  Right-angle dual-headed tomography has increased cardiac SPECT utility by cutting acquisition time in half which enhances gating capabilities. When gating, however, a deceleration in heart rate, due to a return to baseline rate after stress or lessened anxiety at the end of a study, may significantly affect the last step(s) of a gated study with possible frame or information loss. The purpose of this study was to illustrate the artifacts produced in myocardial perfusion studies when a frame or frames are lost in single- and dual-detector SPECT imaging methodologies.
  
  
  METHODS
  A near-normal 99mTc-sestamibi study was obtained using a dual-headed camera system fitted with high-resolution, long-bore collimators. The normal study was processed including all frames (1-32). To demonstrate the effect of losing frames on a dual-headed system, the study was processed three different ways to simulate frame loss.
  
  
  RESULTS
  Loss of frames at the end of a SPECT acquisition results in significant inferoseptal wall defects, left ventricular lumen narrowing, as well as thinning of the anterior and lateral walls. The overall appearance of the heart is a more oval-shaped heart with decreased perfusion. The effect of losing the last frame in a dual-headed camera system as opposed to losing the last frame in a single-headed camera system is more substantial.
  
  
  CONCLUSIONS
  A scan resulting in the loss of a frame in either a single- or a dual-headed camera system creates artifacts in the myocardial wall and should always be repeated. It is significant to note that artifacts present in a dual-headed system are much more prevalent than in a single-headed system due to the nature of dual-headed acquisition parameters.
authors.affiliation: Department of Nuclear Medicine, Harborview Medical Center, Seattle, Washington 98115, USA.
authors.forename: G E
authors.initials: GE
authors.lastname: Wolf
mesh_terms: D016477:Artifacts; D015902:Gamma Cameras; D006321:Heart / Q000000981:diagnostic imaging*; D006346:Heart Septum / Q000000981:diagnostic imaging; D006801:Humans; D010477:Perfusion; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation* / Q000379:methods
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi