title: [Heparin-induced coagulation disturbance from mechanical autotransfusion].
abstract: Disorders in blood coagulation during the use of autotransfusion have been reported in recent literature. We wondered whether or not heparine, remaining in the prepared sample of retransfusion blood might be responsible for these disturbances.
  
  
  METHODS
  Therefore we created a setting in which heparine was added to animal blood in order to imitate clinical situations during the use of the CELL SAVER.
  
  
  RESULTS
  According to our results the blood shows no irregular heparine load as long as the machine is used following the operating instructions. But if the volume of rinsing liquid is decreased or the pumpflow is increased, the heparine load is increased enormously (Table 1).
  
  
  CONCLUSIONS
  If the CELL SAVER is used with reduced volume of rinsing liquid or higher velocity of the pump, the coagulation status of the patient has to be monitored meticously.
authors.affiliation: Abteilung für Anästhesie, Krankenhaus Merheim.
authors.forename: M
authors.initials: M
authors.lastname: Vorweg
authors.forename: G
authors.initials: G
authors.lastname: Muckel
authors.forename: D
authors.initials: D
authors.lastname: Knüttgen
authors.forename: A
authors.initials: A
authors.lastname: Schindler
authors.forename: M
authors.initials: M
authors.lastname: Doehn
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000009:adverse effects* / Q000097:blood; D001778:Blood Coagulation Disorders / Q000139:chemically induced / Q000209:etiology*; D001804:Blood Transfusion, Autologous / Q000009:adverse effects* / Q000295:instrumentation; D006493:Heparin / Q000009:adverse effects* / Q000097:blood; D013552:Swine
chemical_list: D000925:Anticoagulants; D006493:Heparin