Ankylosing spondylitis and genitourinary infection.
One hundred and thirty-four male and 32 female patients with ankylosing spondylitis and 33 women with pure ileitis terminalis Crohn were examined. The study protocol included a medical-rheumatological examination and thorough investigation for genitourinary infection. Urethroadnexitis was found in 37/134 male patients (2 patients suffered from balanitis, 17 patients from urethritis, 18 patients from prostatitis, and 2 patients from epididymitis), 15/32 female patients (11 of them had urethritis and in 4 cases urethritis associated with vaginitis) and 5/33 women with ileitis terminalis (every case with urethritis). The microorganism isolated most frequently from patients with genitourinary infection was Chlamydia trachomatis. The majority of patients with genitourinary infection were HLA-B27 positive. Nevertheless, the following conclusions can be reached: (1) evidence of Chlamydia trachomatis infection is frequent in male and female patients with ankylosing spondylitis, (2) patients with genitourinary infection tend to have HLA-B27, and (3) furthermore, presence of genitourinary infection was not significantly associated with chronic illness.
Lange
U
U
Department of Rheumatology, University Giessen, Ludwigstr. 37-39, D-61231 Bad Nauheim, Germany.EurJMedRes@t-online.de
Teichmann
J
J
D000328:Adult; D002690:Chlamydia Infections / Q000150:complications* / Q000175:diagnosis; D002692:Chlamydia trachomatis; D003424:Crohn Disease / Q000382:microbiology; D005260:Female; D015235:HLA-B Antigens / Q000032:analysis / Q000235:genetics; D006801:Humans; D008297:Male; D011472:Prostatitis / Q000150:complications / Q000175:diagnosis; D012737:Sex Factors; D013167:Spondylitis, Ankylosing / Q000235:genetics / Q000382:microbiology*; D014526:Urethritis / Q000150:complications* / Q000175:diagnosis; D014627:Vaginitis / Q000150:complications / Q000175:diagnosis
D015235:HLA-B Antigens; C103707:HLA-B57 antigen