Medical implications of understanding complex disease traits.
The application of genetic mapping to human disease gene identification has led to the definition of many linkages and a few disease genes in complex traits over the past two years. Its application has also increased to include aspects of pharmacogenetics relating to pharmacokinetics and pharmacodynamics.
Bell
J
J
University of Oxford Level 7 John Radcliffe Hospital Headington Oxford OX3 9DU UK. john.bell@ndm.ox.ac.uk.
D000818:Animals; D001249:Asthma / Q000235:genetics; D001327:Autoimmune Diseases / Q000235:genetics; D003920:Diabetes Mellitus / Q000235:genetics; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D008040:Genetic Linkage; D020022:Genetic Predisposition to Disease; D005826:Genetics, Medical; D006801:Humans; D009765:Obesity