title: Chronic recurrent multifocal osteomyelitis--report of eight patients.
abstract: The authors undertook a retrospective review of the clinical records and radiologic findings of eight children with chronic, recurrent multifocal osteomyelitis (CRMO). This disease is a recognized clinicopathologic entity with typical radiographic findings, mostly in the metaphyses of the long bones. The diagnosis is one of exclusion without pathognomonic findings. The patients were treated with non-steroidal anti-inflammatory drugs. There was no evidence of altered bone growth or abnormal joint development. It is concluded that CRMO is a distinct clinical entity that is different from acute or subacute bacterial osteomyelitis. Recognition of this condition is important to avoid treatment with antibiotics and repeated operations.
authors.affiliation: Department of Paediatrics, University Hospital, Oststrasse 21-25, D-04317 Leipzig, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Handrick
authors.forename: D
authors.initials: D
authors.lastname: Hörmann
authors.forename: A
authors.initials: A
authors.lastname: Voppmann
authors.forename: R
authors.initials: R
authors.lastname: Schille
authors.forename: P
authors.initials: P
authors.lastname: Reichardt
authors.forename: R B
authors.initials: RB
authors.lastname: Tröbs
authors.forename: R P
authors.initials: RP
authors.lastname: Möritz
authors.forename: M
authors.initials: M
authors.lastname: Borte
mesh_terms: D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D011859:Radiography; D012008:Recurrence; D012189:Retrospective Studies
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal