Colon carcinogenesis models for chemoprevention studies.
Every animal model has its strengths and weaknesses; however, some of these models have proven useful in evaluating hereditary factors, whereas other models were found to be useful in understanding the relationship between nutritional factors and colon cancer. We believe that the results obtained by these models, both genetic based and chemically induced, will contribute to the understanding of genetic and nutritional factors as they relate to colon carcinogenesis.
Reddy
B S
BS
American Health Foundation, Valhalla, New York, USA.
D000818:Animals; D018890:Chemoprevention; D003110:Colonic Neoplasms / Q000209:etiology* / Q000517:prevention & control; D004195:Disease Models, Animal