title: [A study of sialylated carbohydrate antigen in patients with benign bronchopulmonary disease].
abstract: We studied the levels of carbohydrate antigen (CA 19-9, SLX, CA 50, Span-1, and Dupan-2) in serum, bronchoalveolar lavage fluid, and tissue from patients with benign bronchopulmonary disease. Patients had bronchiectasis, healed pulmonary tuberculosis, pulmonary fibrosis, or other diseases. Bronchoalveolar lavage fluid levels and immunohistochemical findings for lung tissue samples, in the absence of digestive and other diseases, suggested that elevated serum sialylated Lewis(A) (CA 19-9, CA 50, and Span-1) and Lewis(X) (SLX) antigen in patients with benign broncho-pulmonary disease are due to marked production of sialylated carbohydrate antigen in respiratory bronchioles. Common features of patients with benign bronchopulmonary disease include elevated serum carbohydrate antigen levels and bronchiectasis.
authors.affiliation: High Standard Emergency and Critical Care Medical Center, Kurume University School of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Yokoyama
authors.forename: Y
authors.initials: Y
authors.lastname: Ikedou
authors.forename: F
authors.initials: F
authors.lastname: Kido
authors.forename: S
authors.initials: S
authors.lastname: Tanoue
authors.forename: K
authors.initials: K
authors.lastname: Tashiro
authors.forename: H
authors.initials: H
authors.lastname: Ninomiya
authors.forename: T
authors.initials: T
authors.lastname: Rikimaru
authors.forename: A
authors.initials: A
authors.lastname: Kajiki
authors.forename: M
authors.initials: M
authors.lastname: Takamoto
authors.forename: T
authors.initials: T
authors.lastname: Ishibashi
authors.forename: K
authors.initials: K
authors.lastname: Oizumi
mesh_terms: D000368:Aged; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis* / Q000378:metabolism; D015415:Biomarkers / Q000032:analysis; D001980:Bronchi / Q000378:metabolism; D001987:Bronchiectasis / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D009844:Oligosaccharides / Q000032:analysis* / Q000378:metabolism; D000080506:Sialyl Lewis X Antigen
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate; D015415:Biomarkers; D009844:Oligosaccharides; D000080506:Sialyl Lewis X Antigen