title: Occupational risk factors for prostate cancer mortality in British Columbia, Canada.
abstract: BACKGROUND
  Although prostate cancer is the most common life-threatening cancer among males in North America, relatively little is known about its etiology. We have conducted a proportional mortality study to generate hypotheses concerning occupational risk factors for the disease.
  
  
  METHODS
  Age standardized proportional mortality ratios (PMR) for prostate cancer were calculated for a total of 216 occupations and 88 industries. Separate calculations were done for all male deaths age 20 and up and for deaths that occurred during men's working lifetime (age 20-65).
  
  
  RESULTS
  Elevated mortality from prostate cancer was seen among business owners and managers (PMR = 110; 95% CI = 101-118), brokers (PMR = 184; 95% CI = 122-266), farmers and farm managers (PMR = 112; 95% CI = 105-120), and school teachers (PMR = 133; 95% CI = 101-174). Evaluation by industry shows elevated prostate cancer mortality in agriculture (PMR = 110; 95% CI = 103-118), financial institutions (PMR = 138, 95% CI = 112-170), and transportation equipment manufacture (PMR = 136; 95% CI = 109-168).
  
  
  CONCLUSIONS
  The findings suggest that workers in a number of occupations have elevated risks of prostate cancer including farmers and teachers. More detailed cohort and case-control studies, evaluating specific exposures are required before primary prevention programs in the workplace are feasible.
authors.affiliation: Cancer Control Research Program, BC Cancer Agency, Vancouver, Canada.
authors.forename: J A
authors.initials: JA
authors.lastname: Buxton
authors.forename: R P
authors.initials: RP
authors.lastname: Gallagher
authors.forename: N D
authors.initials: ND
authors.lastname: Le
authors.forename: P R
authors.initials: PR
authors.lastname: Band
authors.forename: J L
authors.initials: JL
authors.lastname: Bert
mesh_terms: D000328:Adult; D000368:Aged; D001955:British Columbia / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016272:Occupational Health; D016016:Proportional Hazards Models; D011471:Prostatic Neoplasms / Q000401:mortality*; D012307:Risk Factors