title: Preoperative chemotherapy of chemoradiotherapy for the treatment of adenocarcinoma of the pancreas and ampulla of Vater.
abstract: Much has been written about preoperative strategies in the treatment of pancreatic adenocarcinoma, yet there has been very little comment concerning other periampullary malignancies. This review discusses current issues relevant to the further development of preoperative adjuvant treatment of pancreatic adenocarcinoma. A small series of patients with ampullary adenocarcinomas treated with preoperative adjuvant chemoradiotherapy is also described.
authors.affiliation: Department of Surgery, Fox Chase Cancer Center, Temple University School of Medicine, 7701 Burholme Ave., Philadelphia, Pennsylvania 19111, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Hoffman
authors.forename: H S
authors.initials: HS
authors.lastname: Cooper
authors.forename: N A
authors.initials: NA
authors.lastname: Young
authors.forename: T K
authors.initials: TK
authors.lastname: Pendurthi
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery / Q000628:therapy*; D014670:Ampulla of Vater; D017024:Chemotherapy, Adjuvant; D003138:Common Bile Duct Neoplasms / Q000601:surgery / Q000628:therapy*; D006801:Humans; D020360:Neoadjuvant Therapy; D010190:Pancreatic Neoplasms / Q000601:surgery / Q000628:therapy*; D011300:Preoperative Care; D018714:Radiotherapy, Adjuvant