title: The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II.
abstract: Cordyceps sinensis (Berk.) Sacc. is a time-honored tonic food and herbal medicine in China, where recent research has shown that many of its traditional uses may be viewed from the basis of pharmacological activities. The ongoing exploration of C. sinensis in its wild form and cultured, fermented mycelial products derived from it, are reviewed from English and Chinese literature. Part II concludes the series with a review of C. sinensis in preclinical in vitro and in vivo studies, and open-label and double-blinded clinical trials on the respiratory, renal, hepatic, cardiovascular, immunologic, and nervous systems, and its effects on cancer, glucose metabolism, inflammatory conditions, and toxicological studies. In Part I, which appeared in the Fall 1998 issue of this journal (4(3):289-303), we discussed the effects of C. sinensis on antisenescence, endocrine and sexual functions, atherosclerosis, hyperlipidemia, and free radicals.
authors.affiliation: Department of Pediatrics, Stanford University School of Medicine, California, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Zhu
authors.forename: G M
authors.initials: GM
authors.lastname: Halpern
authors.forename: K
authors.initials: K
authors.lastname: Jones
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000187:drug effects / Q000378:metabolism; D002319:Cardiovascular System / Q000187:drug effects; D002986:Clinical Trials as Topic; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use*; D006801:Humans; D007107:Immune System / Q000187:drug effects; D007668:Kidney / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008168:Lung / Q000187:drug effects; D009369:Neoplasms / Q000628:therapy; D011660:Pulmonary Heart Disease / Q000628:therapy
chemical_list: D001786:Blood Glucose; D004365:Drugs, Chinese Herbal