[Effects of support++ loads and stimulation of CNS on functional activity of somatotrops and thyreocytes in suspended rats].
In the 14-day experiment with suspended rats there investigated the effect of support loads and stimulated of CNS (ephedrine and strychnine) on functional activity of somatotrops of adenohypophysis and thyrocytes of the thyroid gland. It is shown that the support loads and stimulators of the CNS increase the functional activity of somatotrops and thyreocytes. As this takes place, the loads of support give rise to the elevation of production and secretion of the growth hormone and thyroid hormones whereas ephedrine induces mainly the secretion of growth hormone. It is concluded that the support loads and stimulator of the CNS are able compensate in part a deficit of afferentation developing in the rats during suspension.
Alekseev
E I
EI
Loginov
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VI
Kaplanskiĭ
A S
AS
D000222:Adaptation, Physiological; D000818:Animals; D002490:Central Nervous System / Q000187:drug effects / Q000502:physiology*; D000697:Central Nervous System Stimulants / Q000494:pharmacology; D004809:Ephedrine / Q000494:pharmacology; D018684:Glycine Agents / Q000494:pharmacology; D013006:Growth Hormone / Q000378:metabolism; D019417:Hindlimb Suspension / Q000009:adverse effects; D008297:Male; D010903:Pituitary Gland, Anterior / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D051381:Rats; D013331:Strychnine / Q000494:pharmacology; D013961:Thyroid Gland / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D013963:Thyroid Hormones / Q000378:metabolism; D016474:Weight-Bearing / Q000502:physiology*
D000697:Central Nervous System Stimulants; D018684:Glycine Agents; D013963:Thyroid Hormones; D013006:Growth Hormone; D004809:Ephedrine; D013331:Strychnine