[Conditioned reflex activity in rats after chronic antenatal gamma irradiation in association with mercazolyl].
The purpose of investigation is the study of combined influence of gamma-radiation (137Cs, 1.25 Gy during 20 days) and mercazolyl (20 mg/100 ml drinkable water) in utero on the intellectual state of rats in the postnatal ontogenesis. It was shown, that antenatal separate influence both of gamma-radiation and mercazolyl induced the delay of intellectual development in 2 and 7 months age. The combined influence of these factors induced essential increase observed effect. There is a party of the conditioned reflex activity in 7 month age.
Pavlova
L N
LN
Medical Radiological Research Center, Russian Academy of Medical Science, Obninsk.
Izmest'eva
O S
OS
Zhavoronkov
L P
LP
D000367:Age Factors; D000818:Animals; D013956:Antithyroid Agents / Q000494:pharmacology*; D003214:Conditioning, Classical / Q000187:drug effects* / Q000528:radiation effects*; D005260:Female; D005333:Fetus / Q000187:drug effects* / Q000528:radiation effects*; D005720:Gamma Rays; D008297:Male; D008713:Methimazole / Q000494:pharmacology*; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
D013956:Antithyroid Agents; D008713:Methimazole