Carbamazepine in the treatment of Lyme disease-induced hyperacusis.
Lyme disease-induced hyperacusis can be an intensely disabling, chronic condition that is accompanied by posttraumatic stress disorder-like psychobehavioral sequelae. The authors describe effective treatment of 2 patients with carbamazepine. Speculations regarding a mode of action are offered.
Nields
J A
JA
Department of Psychiatry, Yale University, New Haven, Connecticut, USA.
Fallon
B A
BA
Jastreboff
P J
PJ
D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D002220:Carbamazepine / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006941:Hyperesthesia / Q000188:drug therapy* / Q000209:etiology; D007696:Kindling, Neurologic / Q000187:drug effects; D008144:Loudness Perception / Q000187:drug effects*; D008193:Lyme Disease / Q000150:complications*; D012684:Sensory Thresholds / Q000187:drug effects*