title: Urticaria following varicella vaccine associated with gelatin allergy.
abstract: An uncommon reaction to varicella vaccine has been urticaria. Based on two reports of urticaria believed to be due to gelatin in recipients of measles-mumps-rubella vaccine, we suspected gelatin as the cause of generalized urticaria in two children after varicella vaccination. Intradermal testing with gelatin yielded a wheal and flare reaction in both children. We conclude that children known to be allergic to gelatin should not receive Oka/Merck varicella vaccine (VARIVAX).
authors.affiliation: Department of Pediatrics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
authors.forename: S
authors.initials: S
authors.lastname: Singer
authors.forename: C E
authors.initials: CE
authors.lastname: Johnson
authors.forename: R
authors.initials: R
authors.lastname: Mohr
authors.forename: C
authors.initials: C
authors.lastname: Holowecky
mesh_terms: D000485:Allergens / Q000276:immunology*; D000818:Animals; D019433:Chickenpox Vaccine / Q000009:adverse effects*; D002675:Child, Preschool; D004342:Drug Hypersensitivity; D005260:Female; D005780:Gelatin / Q000276:immunology*; D006801:Humans; D008297:Male; D012882:Skin Tests; D013552:Swine; D014581:Urticaria / Q000276:immunology*