title: Brachytherapy in early prostate cancer--early experience.
abstract: Use of brachytherapy with radioactive seeds in the management of early prostate cancer is commonly used in the United States. The early experience has been reported from the prostate treatment centers in Seattle for the last 10 years. In this manuscript we are reporting our early experience of 150 radioactive seed implantations in early stage prostate cancer using either Iodine 125 or Palladium 103 seeds. The average age of the patient is 66 years and the median Gleason score is 5.4 with a median PSA of 6. A brief description of the evolution of the treatment of prostate cancer as well as the preparation for the seed implantation using the volume study with ultrasound of the prostate, pubic arch study using CT scan of the pelvis and the complete planning using the treatment planning computers are discussed. We also have described the current technique which is used in our experience based on the Seattle guidelines. We plan a follow-up report with the results of the studies with longer follow-up.
authors.affiliation: Department of Radiation Oncology, James Graham Brown Cancer Center, USA.
authors.forename: B O
authors.initials: BO
authors.lastname: Jose
authors.forename: J L
authors.initials: JL
authors.lastname: Bailen
authors.forename: F H
authors.initials: FH
authors.lastname: Albrink
authors.forename: G S
authors.initials: GS
authors.lastname: Steinbock
authors.forename: M S
authors.initials: MS
authors.lastname: Cornett
authors.forename: D C
authors.initials: DC
authors.lastname: Benson
authors.forename: W K
authors.initials: WK
authors.lastname: Schmied
authors.forename: R N
authors.initials: RN
authors.lastname: Medley
authors.forename: W J
authors.initials: WJ
authors.lastname: Spanos
authors.forename: K J
authors.initials: KJ
authors.lastname: Paris
authors.forename: P D
authors.initials: PD
authors.lastname: Koerner
authors.forename: R A
authors.initials: RA
authors.lastname: Gatenby
authors.forename: D L
authors.initials: DL
authors.lastname: Wilson
authors.forename: R
authors.initials: R
authors.lastname: Meyer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D001918:Brachytherapy; D003663:Decision Trees; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D016896:Treatment Outcome