title: Percutaneous mechanical mitral commissurotomy with a newly designed metallic valvulotome: immediate results of the initial experience in 153 patients.
abstract: BACKGROUND
  Percutaneous balloon valvotomy has become a common treatment of mitral stenosis, but the cost of the procedure remains a limitation in countries with restricted financial resources, leading to a frequent reuse of the disposable catheters. To overcome this limitation, a reusable metallic valvotomy device has been developed with the goals of both improving the mitral valvotomy results and decreasing the cost of the procedure.
  
  
  RESULTS
  The device consists of a detachable metallic cylinder with 2 articulated bars screwed onto the distal end of a disposable catheter whose proximal end is connected to an activating pliers. By the transseptal route, the device is advanced across the valve over a traction guidewire. Squeezing the pliers opens the bars up to a maximum extent of 40 mm. The clinical experience consisted of 153 patients with a broad spectrum of mitral valve deformities. The procedure was successful in 92% of cases and resulted in a significant increase in mitral valve area, from 0.95+/-0.2 to 2. 16+/-0.4 cm2. No increase in mitral regurgitation was noted in 80% of cases. Bilateral splitting of the commissures was observed in 87%. Complications were 2 cases of severe mitral regurgitation (1 requiring surgery), 1 pericardial tamponade, and 1 transient cerebrovascular embolic event. In this series, the maximum number of consecutive patients treated with the same device was 35.
  
  
  CONCLUSIONS
  The results obtained with this new device are encouraging and at least comparable to those of current balloon techniques. Multiple uses after sterilization should markedly decrease the procedural cost, a major advantage in countries with limited resources and high incidence of mitral stenosis.
authors.affiliation: Charles Nicolle Hospital, Department of Cardiology , University of Rouen, France. alain.cribier@chu-rouen.fr
authors.forename: A
authors.initials: A
authors.lastname: Cribier
authors.forename: H
authors.initials: H
authors.lastname: Eltchaninoff
authors.forename: R
authors.initials: R
authors.lastname: Koning
authors.forename: P C
authors.initials: PC
authors.lastname: Rath
authors.forename: R
authors.initials: R
authors.lastname: Arora
authors.forename: A
authors.initials: A
authors.lastname: Imam
authors.forename: M
authors.initials: M
authors.lastname: El-Sayed
authors.forename: S
authors.initials: S
authors.lastname: Dani
authors.forename: G
authors.initials: G
authors.lastname: Derumeaux
authors.forename: J
authors.initials: J
authors.lastname: Benichou
authors.forename: C
authors.initials: C
authors.lastname: Tron
authors.forename: S
authors.initials: S
authors.lastname: Janorkar
authors.forename: G
authors.initials: G
authors.lastname: Pontier
authors.forename: B
authors.initials: B
authors.lastname: Letac
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D021721:Balloon Occlusion; D002305:Cardiac Tamponade / Q000209:etiology; D002404:Catheterization / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods*; D002648:Child; D018618:Echocardiography, Doppler, Color; D017743:Equipment Reuse; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000628:therapy; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging / Q000628:therapy*; D011183:Postoperative Complications; D011237:Predictive Value of Tests; D013525:Surgical Instruments