title: Impact of genetic counseling on primary and preventive care in obstetrics and gynecology.
abstract: OBJECTIVE
  To evaluate the utility of the prenatal three-generation pedigree in assessment of the obstetric patient's primary medical risks.
  
  
  METHODS
  In a case series, 250 charts of patients referred for amniocentesis on the basis of advanced maternal age were reviewed for a significant genetic risk of a primary care disorder.
  
  
  RESULTS
  A total of 40 patients (16%) were at significantly increased risk for a primary care disorder. Thirty-eight patients (15.2%) were at increased risk for medical conditions for which early screening, detection and/or intervention are established.
  
  
  CONCLUSIONS
  For the advanced maternal age population, formal genetic risk assessment performed prior to amniocentesis can be beneficial in primary care risk assessment.
authors.affiliation: Department of Obstetrics and Gynecology, Tufts University School of Medicine, Baystate Medical Center, Springfield, Massachusetts, USA.
authors.forename: G M
authors.initials: GM
authors.lastname: Cohn
authors.forename: R C
authors.initials: RC
authors.lastname: Miller
authors.forename: M
authors.initials: M
authors.lastname: Gould
authors.forename: C J
authors.initials: CJ
authors.lastname: Macri
authors.forename: M L
authors.initials: ML
authors.lastname: Gimovsky
mesh_terms: D000328:Adult; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D008423:Maternal Age; D008499:Medical Records; D009774:Obstetrics; D010375:Pedigree; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D011320:Primary Health Care; D018570:Risk Assessment