title: Karyotype evolution in a case of uterine angioleiomyoma.
abstract: Clonal karyotypic alterations of a uterine angioleiomyoma of a 41-year-old woman are reported. Cytogenetically a stemline of the tumor and two related subclones with additional abnormalities due to karyotypic evolution were identified: 46,X,t(X;11)(p11.4;p15)/46, idem,inv(2)(p15q13)/46, idem,inv(2)(p15q13),t(5;20)(q13;q13.2). None of the aberrations observed in the present case has been reported in uterine smooth muscle tumors before.
authors.affiliation: Center of Human Genetics and Genetic Counselling, University of Bremen, Germany.
authors.forename: Y
authors.initials: Y
authors.lastname: Hennig
authors.forename: J
authors.initials: J
authors.lastname: Caselitz
authors.forename: C
authors.initials: C
authors.lastname: Stern
authors.forename: S
authors.initials: S
authors.lastname: Bartnitzke
authors.forename: J
authors.initials: J
authors.lastname: Bullerdiek
mesh_terms: D000328:Adult; D018229:Angiomyoma / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D007446:Chromosome Inversion; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D005260:Female; D006801:Humans; D007621:Karyotyping; D014178:Translocation, Genetic; D014594:Uterine Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D014960:X Chromosome