[Investigations of drug release containing Cremophor emulsifiers].
Release of poorly soluble drug from several creams containing 50-75% water was investigated and the dependence of liberation on the emulsifier- and water content was established. The emulsifier content vs. liberation function can be described with a maximum curve, the relationship between drug release and viscosity can be characterized by a reciprocal or a logarithmic function.
István
E
E
SZOTE Gyógyszertechnológiai Intézet, Szeged.
Zsuzsanna
M
M
Tünde
K
K
Annamária
C
C
Ildikó
C
C
D002626:Chemistry, Pharmaceutical / Q000379:methods; D003692:Delayed-Action Preparations; D004655:Emulsions; D009824:Ointments; D011092:Polyethylene Glycols; D014867:Water