Jumping translocation of 1q as the sole aberration in a case of follicular lymphoma.
Cytogenetic and fluorescence in situ hybridization (FISH) studies in a case of follicular lymphoma grade III showed a "jumping translocation" of chromosome 1q21-qter to chromosomes Xq28 and 18q23, which resulted in a partial trisomy 1q as the only chromosome aberration. This case represents, to the best of our knowledge, the first report of a jumping translocation in a malignant lymphoma occurring as the sole aberration.
Rosenwald
A
A
Institute of Pathology, University of Würzbrug, Germany.
Ott
G
G
Katzenberger
T
T
Siebert
R
R
Kalla
J
J
Kuse
R
R
Ott
M M
MM
Müller-Hermelink
H K
HK
Schlegelberger
B
B
D002871:Chromosome Banding; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D002887:Chromosomes, Human, Pair 18; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008198:Lymph Nodes / Q000473:pathology; D008224:Lymphoma, Follicular / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged; D014178:Translocation, Genetic; D014407:Tumor Cells, Cultured; D014960:X Chromosome