title: [The organ-conserving treatment of early carcinoma of the breast. I. The biological, histological and radiobiological bases. II. Radiotherapy--an essential component in the organ-conserving surgery of early carcinoma of the breast].
abstract: One of the major achievements in the last 20 years is the awareness that mutilating surgery--mastectomy--is a biologically obsolete therapeutic approach, and no longer indicated in the treatment of early breast cancer which in turn, has a dramatic effect insofar as mammary gland preservation is obviously an important consideration for each woman. Either of the operative procedures--quadrantectomy and lumpectomy--should be by all means followed by radiotherapy with a view to control local recurrences of the process. Clinical trials covering borderline disciplines assay the contribution of the answers to a number of questions, as follows: 1) Is the effect of conservative mammary gland treatment comparable to that of mastectomy? 2) Is radiotherapy an essential component of conservative breast surgery? 3) Is conservative surgery indicated in all cases presenting early breast carcinoma? 4) Which are the factors exerting influence on the conservative therapeutic approach to breast cancer?
authors.forename: V
authors.initials: V
authors.lastname: Pŭrvanova
mesh_terms: D001940:Breast / Q000473:pathology / Q000601:surgery*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D002277:Carcinoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008327:Mammography; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D013997:Time Factors