title: [Familial occurrence of chronic tension headache].
abstract: Chronic tension-type headache occurs in 3% of the Danish population. the aetiology remains an enigma, even though it is one of the most frequent illnesses with chronic pain. A family study indicates the importance of genetic factors. Compared with the general population, first degree relatives (parents, siblings and children) of probands with chronic tension-type headache have a three-fold significantly increased risk of chronic tension-type headache, while spouses had no increased risk. Complex segregation analysis indicates multifactorial inheritance. Thus, a combination of genetic and environmental factors causes chronic tension-type headache.
authors.affiliation: Neurologisk afdeling, Amtssygehuset i Glostrup.
authors.forename: H
authors.initials: H
authors.lastname: Friederichs
authors.forename: J
authors.initials: J
authors.lastname: Olesen
authors.forename: M B
authors.initials: MB
authors.lastname: Russell
mesh_terms: D000328:Adult; D003718:Denmark / Q000453:epidemiology; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D018781:Tension-Type Headache / Q000453:epidemiology / Q000209:etiology / Q000235:genetics*