The use of arterial allografts in aortic graft infections. A three year experience on eighteen patients.
BACKGROUND
We describe our experience in the treatment of aortic graft infections by replacing them with arterial homografts as suggested by the good results recently described.


METHODS
Between March 1994 and March 1997 eighteen patients with infections of the aortofemoral bifurcation segments have been treated. All patients underwent a complete explantation of the infected graft and an in situ revascularization with arterial homograft harvested in multiorgan removal. Eight segments were freshly preserved, 10 were cryopreserved. Four patients were operated as emergencies, of which 3 for aorto-enteric fistulas. All others presented a serious septic state.


RESULTS
Three patients died in the early postoperative period: one of acute infarction and two of homograft related causes. In the follow-up there was only one death from acute infarction, a branch occlusion and two allograft enteric fistulas successfully treated by surgery. All surviving patients are submitted to periodical haemodynamic and tomographic control with an average follow-up of 22 months (range 3 months to 3 years) and there has been no allograft degeneration so far.


CONCLUSIONS
The use of homologue arterial allografts has shown good results in the treatment of serious aortic graft infections resulting in adequate peripheral vascularization. There have been no significant degenerations to date, either in fresh or cryopreserved allografts.
Locati
P
P
Department of Vascular Surgery Busto Arsizio Hospital, Italy.
Novali
C
C
Socrate
A M
AM
Costantini
E
E
Morlacchi
E
E
Piazzalunga
G
G
Costantini
S
S
D000368:Aged; D001012:Aorta, Abdominal / Q000601:surgery; D001158:Arteries / Q000637:transplantation*; D001167:Arteritis / Q000382:microbiology / Q000401:mortality / Q000601:surgery*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects* / Q000382:microbiology; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects; D015925:Cryopreservation; D005260:Female; D005263:Femoral Artery / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000382:microbiology / Q000401:mortality / Q000601:surgery*; D012086:Reoperation; D012189:Retrospective Studies; D015996:Survival Rate; D014184:Transplantation, Homologous; D016896:Treatment Outcome