title: Successful repair of cardio-Behçet's disease with aortic and mitral regurgitation.
abstract: A case of Behçet's disease with cardiac involvement of aortic and mitral regurgitation is presented. The patient underwent aortic and mitral valve replacement, along with plication of the ascending aorta. Histological examination revealed chronic inflammation with degenerative changes, consistent with Behçet's disease. Anti-inflammatory therapy using prednisolone was maintained throughout the postoperative period. This is the first case of cardio-Behçet's disease surgically treated for both aortic and mitral valves with a successful long-term survival.
authors.affiliation: Department of Cardiovascular Surgery, Hokkaido University, Sapporo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Zakaria
authors.forename: S
authors.initials: S
authors.lastname: Sasaki
authors.forename: Y
authors.initials: Y
authors.lastname: Matsui
authors.forename: N
authors.initials: N
authors.lastname: Shiiya
authors.forename: T
authors.initials: T
authors.lastname: Murashita
authors.forename: K
authors.initials: K
authors.lastname: Yasuda
mesh_terms: D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D002315:Cardiopulmonary Bypass; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control; D011239:Prednisolone / Q000627:therapeutic use