title: Childhood stress and symptoms of drug dependence in adolescence and early adulthood: social phobia as a mediator.
abstract: Retrospective data from 7,871 individuals age 16 to 64 were used to investigate whether, among those diagnosed with lifetime social phobia, its symptoms serve to link life events and chronic strains in childhood with symptoms of drug dependence in adulthood. Findings suggest social phobia as a pathway through which early life events and chronic strains affect the development of drug-related problems. Implications for research and clinical practice are discussed.
authors.affiliation: Centre for Addiction and Mental Health, Addiction Research Foundation Division, London, Ont.
authors.forename: D J
authors.initials: DJ
authors.lastname: DeWit
authors.forename: K
authors.initials: K
authors.lastname: MacDonald
authors.forename: D R
authors.initials: DR
authors.lastname: Offord
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior; D000328:Adult; D015984:Causality; D002648:Child; D002657:Child Development; D004198:Disease Susceptibility; D005260:Female; D006306:Health Surveys; D006801:Humans; D008016:Life Change Events; D008297:Male; D008875:Middle Aged; D008960:Models, Psychological; D009864:Ontario / Q000453:epidemiology; D010698:Phobic Disorders / Q000150:complications / Q000453:epidemiology*; D012189:Retrospective Studies; D012919:Social Behavior; D013223:Statistics as Topic; D013315:Stress, Psychological / Q000150:complications / Q000453:epidemiology*; D019966:Substance-Related Disorders / Q000453:epidemiology* / Q000209:etiology