Pediatric renal tumors.
A broad spectrum of renal tumors occurs in infants and children ranging from the benign cystic nephroma to the extremely aggressive malignant rhabdoid tumor of the kidney. A thorough understanding of these tumors is crucial to the optimal diagnosis and management of children with renal masses. The common renal tumors in infants and children are discussed and an orderly method for their evaluation is presented. Recent developments in the molecular biology of Wilms' tumor are outlined to provide insight into the origin of this tumor.
Shamberger
R C
RC
Children's Hospital and the Harvard Medical School, Boston, Massachusetts 02115, USA. Shamberger@A1.TCH.Harvard.edu
D000293:Adolescent; D000465:Algorithms; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D018201:Nephroma, Mesoblastic / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D015996:Survival Rate; D009396:Wilms Tumor / Q000175:diagnosis / Q000473:pathology / Q000628:therapy