Cycle control with oral contraceptives: A review of the literature.
Comparing the degree of cycle control provided by various oral contraceptives is problematic. The inherent limitations, small demonstrated differences, and differing methods of data presentation characteristic of these trials support the conclusion that it is almost impossible to compare the bleeding patterns of one preparation with those of another. Chlamydial infection, smoking, and inconsistency of use are factors that have significant effects on rates of spotting and breakthrough bleeding. Clinicians must alert patients to the possibility of intermenstrual bleeding and educate them with regard to the importance of continued, consistent oral contraceptive use to minimize those problems among pill users in their practices.
Thorneycroft
I H
IH
Department of Obstetrics and Gynecology, University of South Alabama School of Medicine, Mobile 36617, USA.
D002690:Chlamydia Infections / Q000150:complications; D002986:Clinical Trials as Topic; D003271:Contraceptive Agents, Female; D003276:Contraceptives, Oral / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced / Q000628:therapy; D006801:Humans; D008597:Menstrual Cycle / Q000187:drug effects*; D008599:Menstruation Disturbances / Q000139:chemically induced / Q000628:therapy; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects