Blood lead levels in children with neurological disorders.
Blood lead levels were measured by atomic absorption spectrometry in 82 children suffering from various neurological disorders (cerebral palsy 42, seizure disorders 35, acute encephalopathy of unknown origin 5) and in 28 healthy children, aged 1 to 12 years. Mean blood lead levels were 11.96 +/- 10.97 micrograms/dl in control children and 19.30 +/- 17.65 micrograms/dl in children with neurological disorders. A significant number of control children as well as those who had neurological disorders were found to have blood lead concentrations of > or = 10 micrograms/dl and > or = 20 micrograms/dl, the cut-off limits for lead poisoning and medical evaluation, respectively. Blood lead levels were, statistically, elevated in children with cerebral palsy compared to controls. Children with pica behaviour exhibited higher blood lead concentrations.
Kumar
A
A
Department of Paediatrics, Faculty of Science, Banaras Hindu University, Varanasi, India.
Dey
P K
PK
Singla
P N
PN
Ambasht
R S
RS
Upadhyay
S K
SK
D002493:Central Nervous System Diseases / Q000097:blood* / Q000209:etiology; D002547:Cerebral Palsy / Q000097:blood / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D004679:Encephalomyelitis / Q000097:blood / Q000209:etiology; D005260:Female; D006801:Humans; D007194:India; D007854:Lead / Q000097:blood*; D007855:Lead Poisoning / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D008297:Male; D010842:Pica / Q000150:complications; D012016:Reference Values; D018570:Risk Assessment; D012640:Seizures / Q000097:blood / Q000209:etiology