title: Multiple intracerebral metastases of a 17-year-old girl with previously diagnosed neurofibromatosis type I.
abstract: We report a case of a 17-year-old girl with multiple intracerebral tumors. Previously, a neurofibroma in the posterior mediastinum and neurofibromatosis had been diagnosed. She developed a spastic tetraparesis with a prominent hemiparesis of the right side within several weeks. On admission we found clinical signs of elevated intracranial pressure. Cranial CT and MRI scans showed multiple space-occupying intracerebral tumors, thought to be multiple meningeoma. The patient was referred to the neurosurgical department, where two of the intracerebral tumors were excised. The histological examination revealed metastases of a neurosarcoma.
authors.affiliation: Department of Neurology, University of Essen, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Maschke
authors.forename: O
authors.initials: O
authors.lastname: Kastrup
authors.forename: V
authors.initials: V
authors.lastname: Reinhardt
authors.forename: M
authors.initials: M
authors.lastname: Keidel
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000556:secondary; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009456:Neurofibromatosis 1 / Q000175:diagnosis*; D018319:Neurofibrosarcoma / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed