The role of Malassezia species in the ecology of human skin and as pathogens.
The new taxonomic structure of the lipophilic genus Malassezia was presented with key characteristics for the seven described species. Among techniques used for epidemiological surveys, the pulsed field gel electrophoresis (PFGE) was found to be of little value in contrast to randomly amplified polymorphic DNA (RAPD). Immunological studies still yielded conflicting results but at least the immunomodulatory capacity of Malassezia yeasts appeared to be related to the cell wall lipids. A review of Malassezia infections together with the present consensus for their prevention and treatment was also made.
Guého
E
E
Mycology Unit, Pasteur Institute, Paris, France.
Boekhout
T
T
Ashbee
H R
HR
Guillot
J
J
Van Belkum
A
A
Faergemann
J
J
D000908:Antibodies, Fungal / Q000097:blood / Q000276:immunology; D003881:Dermatomycoses / Q000188:drug therapy / Q000453:epidemiology* / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D007111:Immunity, Cellular; D008290:Malassezia / Q000145:classification* / Q000235:genetics / Q000276:immunology*; D017720:Molecular Epidemiology; D016533:Mycological Typing Techniques; D012867:Skin / Q000276:immunology / Q000382:microbiology*