Impact of genetic counseling on primary and preventive care in obstetrics and gynecology.
OBJECTIVE
To evaluate the utility of the prenatal three-generation pedigree in assessment of the obstetric patient's primary medical risks.


METHODS
In a case series, 250 charts of patients referred for amniocentesis on the basis of advanced maternal age were reviewed for a significant genetic risk of a primary care disorder.


RESULTS
A total of 40 patients (16%) were at significantly increased risk for a primary care disorder. Thirty-eight patients (15.2%) were at increased risk for medical conditions for which early screening, detection and/or intervention are established.


CONCLUSIONS
For the advanced maternal age population, formal genetic risk assessment performed prior to amniocentesis can be beneficial in primary care risk assessment.
Cohn
G M
GM
Department of Obstetrics and Gynecology, Tufts University School of Medicine, Baystate Medical Center, Springfield, Massachusetts, USA.
Miller
R C
RC
Gould
M
M
Macri
C J
CJ
Gimovsky
M L
ML
D000328:Adult; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D008423:Maternal Age; D008499:Medical Records; D009774:Obstetrics; D010375:Pedigree; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D011320:Primary Health Care; D018570:Risk Assessment