title: Changes in corneal topography after laser in situ keratomileusis for myopia.
abstract: OBJECTIVE
  To define qualitative patterns of corneal topography after excimer laser in situ keratomileusis (LASIK) and to assess whether epithelial hyperplasia occurred after LASIK.
  
  
  METHODS
  A consecutive series of 18 myopic eyes of 10 patients having refractive surgery in an academic practice at the Royal Victorian Eye and Ear Hospital, Melbourne, Australia was followed prospectively after LASIK. Four eyes were treated with the VISX 20/20 excimer laser and 14 eyes were treated with the Nidek EC5000 excimer laser. Videokeratography was performed on each eye at 1, 3, and 6 months after surgery. The common digital subtraction topographic patterns were classified and used to speculate whether epithelial hyperplasia occurred.
  
  
  RESULTS
  After LASIK, 83% of subtraction maps at 1 month and 81% at both 3 and 6 months showed steepening in the ablation zone. There was no clear correlation between the topographic maps and spectacle-corrected visual acuity or regression of the initial effect after surgery.
  
  
  CONCLUSIONS
  Corneal topographic changes similar to those seen after photorefractive keratectomy (PRK) occur after LASIK for myopia.
authors.affiliation: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.
authors.forename: N H
authors.initials: NH
authors.lastname: Barker
authors.forename: T A
authors.initials: TA
authors.lastname: Couper
authors.forename: H R
authors.initials: HR
authors.lastname: Taylor
mesh_terms: D000328:Adult; D003315:Cornea / Q000473:pathology* / Q000601:surgery; D019781:Corneal Topography; D016039:Corneal Transplantation / Q000379:methods*; D019573:Epithelium, Corneal / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000473:pathology* / Q000601:surgery*; D011183:Postoperative Complications; D012029:Refraction, Ocular; D016896:Treatment Outcome; D014792:Visual Acuity