[Holoprosencephaly with neurogenic hypernatremia].
BACKGROUND
Semi-lobar holoprosencephalies can be seldom complicated by neurogenic hypernatremia, which must be distinguished from other causes of hypernatremia.


METHODS
In two admitted children with semi-lobar holoprosencephaly, 7 months and 4 years old, biological data revealed chronic hypernatremia and hyperosmolarity without clinical signs of dehydration, which were finally attributed to a neurogenic hypernatremia.


CONCLUSIONS
Neurogenic hypernatremia must be clearly differentiated from other causes of hypernatremia since it never causes specific complications.
Cuisset
J M
JM
Service des maladies infectieuses et de neurologie infantiles, CHRU de Lille, hôpital Roger-Salengro, Lille.
Cuvellier
J C
JC
Vallée
L
L
Ryckewäert
P
P
Soto-Ares
G
G
Nuyts
J P
JP
D002675:Child, Preschool; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004569:Electroencephalography; D005260:Female; D016142:Holoprosencephaly / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D006955:Hypernatremia / Q000097:blood / Q000209:etiology*; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008831:Microcephaly / Q000150:complications; D009994:Osmolar Concentration