title: [Holoprosencephaly with neurogenic hypernatremia].
abstract: BACKGROUND
  Semi-lobar holoprosencephalies can be seldom complicated by neurogenic hypernatremia, which must be distinguished from other causes of hypernatremia.
  
  
  METHODS
  In two admitted children with semi-lobar holoprosencephaly, 7 months and 4 years old, biological data revealed chronic hypernatremia and hyperosmolarity without clinical signs of dehydration, which were finally attributed to a neurogenic hypernatremia.
  
  
  CONCLUSIONS
  Neurogenic hypernatremia must be clearly differentiated from other causes of hypernatremia since it never causes specific complications.
authors.affiliation: Service des maladies infectieuses et de neurologie infantiles, CHRU de Lille, hôpital Roger-Salengro, Lille.
authors.forename: J M
authors.initials: JM
authors.lastname: Cuisset
authors.forename: J C
authors.initials: JC
authors.lastname: Cuvellier
authors.forename: L
authors.initials: L
authors.lastname: Vallée
authors.forename: P
authors.initials: P
authors.lastname: Ryckewäert
authors.forename: G
authors.initials: G
authors.lastname: Soto-Ares
authors.forename: J P
authors.initials: JP
authors.lastname: Nuyts
mesh_terms: D002675:Child, Preschool; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004569:Electroencephalography; D005260:Female; D016142:Holoprosencephaly / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D006955:Hypernatremia / Q000097:blood / Q000209:etiology*; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008831:Microcephaly / Q000150:complications; D009994:Osmolar Concentration