Synthesis and nematocidal activity of diarylnonanoids related to malabaricones.
Twenty diarylnonanones were synthesized and their nematocidal activity was examined. Among those, the p-hydroxy compound 16 exhibited the strongest activity comparable to the natural diarylnonanoids, malabaricones A and C. Diarylundecanoid 57 also showed appreciable activity.
Hosoi
S
S
Faculty of Pharmaceutical Sciences, Kanazawa University, Japan.
Kiuchi
F
F
Nakamura
N
N
Imasho
M
M
Ali
M A
MA
Sasaki
Y
Y
Tanaka
E
E
Tsumamoto
Y
Y
Kondo
K
K
Tsuda
Y
Y
D000473:Alkanes / Q000138:chemical synthesis / Q000494:pharmacology; D000969:Antinematodal Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D012118:Resorcinols / Q000138:chemical synthesis* / Q000494:pharmacology*; D013329:Structure-Activity Relationship