Susceptibility to tropical theileriosis of calves born to dams immunized with Theileria annulata (Hisar) cell culture vaccine.
The susceptibility/immune status to tropical theileriosis of calves born of immunized dams was evaluated. Six cows were vaccinated with the Theileria annulata cell culture vaccine in the eighth month of pregnancy. Sera from the immunized dams exhibited very high post-vaccination antibody titres as determined by the indirect fluorescent antibody (IFA) test. The calves born to these dams did not show antibodies against T. annulata at the time of birth (IFA titres of < 1:20). The new-born calves were fed colostrum from their mothers and were challenged with T. annulata-infected ground tick supernate at 5-7 days of age. All the calves developed fever (from day 5-6 onwards) and parasitological reactions (from day 8-9 onwards) after challenge. There was a significant decrease in the haemoglobin and packed cell volume of the calves after challenge. All the calves showed signs of acute theileriosis by day 9-10 after challenge and had to be treated with buparvaquone in order to save their lives. The study indicated that detectable levels of anti-theilerial antibodies were not transferred from immune dams to their offspring. All the calves born to immunized dams were fully susceptible to theileriosis and thus themselves needed vaccination.
Beniwal
R K
RK
Department of Veterinary Medicine, Chaudhary Charan Singh Haryana Agricultural University, Hisar, India.
Sharma
R D
RD
Nichani
A K
AK
D000818:Animals; D000831:Animals, Newborn; D000913:Antibodies, Protozoan / Q000097:blood; D000953:Antigens, Protozoan / Q000276:immunology; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001096:Arachnid Vectors / Q000276:immunology; D001831:Body Temperature; D002417:Cattle; D004198:Disease Susceptibility; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect / Q000662:veterinary; D006400:Hematocrit / Q000662:veterinary; D006454:Hemoglobins / Q000032:analysis; D007112:Immunity, Maternally-Acquired / Q000276:immunology*; D007194:India; D009285:Naphthoquinones / Q000627:therapeutic use; D016052:Protozoan Vaccines / Q000276:immunology; D016796:Theileria annulata / Q000276:immunology*; D013801:Theileriasis / Q000276:immunology* / Q000517:prevention & control; D013987:Ticks / Q000276:immunology; D014611:Vaccination / Q000662:veterinary*