title: Major complications of percutaneous embolization of skull-base tumors.
abstract: The technique of direct intratumoral injection of permanent liquid polymerizing agent was initially described in 1994 and has evolved significantly with experience. We report complications that occurred in two patients during injection of Histoacryl and offer suggestions to prevent such complications in the future. In one patient, the glue settled in the right middle cerebral artery; in the second, the glue entered the left ophthalmic artery through a collateral branch. Although the fundamental injection technique has not changed, we suggest additional precautions and modifications to make this procedure a safer and more valuable element in the overall management of patients with difficult skull-base tumors.
authors.affiliation: Department of Diagnostic and Interventional Neuroradiology, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Casasco
authors.forename: E
authors.initials: E
authors.lastname: Houdart
authors.forename: A
authors.initials: A
authors.lastname: Biondi
authors.forename: H S
authors.initials: HS
authors.lastname: Jhaveri
authors.forename: D
authors.initials: D
authors.lastname: Herbreteau
authors.forename: A
authors.initials: A
authors.lastname: Aymard
authors.forename: J J
authors.initials: JJ
authors.lastname: Merland
mesh_terms: D000293:Adolescent; D018322:Angiofibroma / Q000000981:diagnostic imaging / Q000628:therapy*; D002536:Cerebral Arteries / Q000000981:diagnostic imaging; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D004659:Enbucrilate / Q000008:administration & dosage; D006801:Humans; D007267:Injections / Q000009:adverse effects*; D008297:Male; D019300:Medical Errors; D009303:Nasopharyngeal Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D009880:Ophthalmic Artery / Q000000981:diagnostic imaging; D011859:Radiography; D019292:Skull Base Neoplasms / Q000628:therapy