title: [The solitary rectal ulcer today. A review of the literature].
abstract: The solitary rectal ulcer (SRU) is a benign lesion of adults of either sex, which presents with chronic constipation, peculiar defecatory disorders, rectal prolapse and smaller psychological abnormalities. The characteristic appearance of this disease is a "neither being always ulcerate, nor always solitary" lesion, but often with polypoid or granular feature, typically localized in anterior rectal wall, a few inches from anal channel. Distinctive histopathological specimens are localized mucosal distortion, hypertrophic proliferation of muscularis mucosae and obliteration of lamina propria by fibroblasts and muscle fibres from the muscularis mucosae. Very few intermittent or recurrent symptoms are rectal bleeding and mucous discharge with defecations, difficulty of a complete ampullar evacuation and sometimes pelvic or rectoperineal pain. Clinical picture and endoscopic biopsies led to diagnosis. Barium enema, defecography, transrectal ultrasound, manometry and electromyography have an additional role. Medical treatment is performed by high-fiber diet, but biofeedback training is very helpful. Surgical management is as an excisional surgery, as a rectopexy if there is prolapse. Fecal diversion and rectocolic resection are considered only for patients with obstinate and severe symptoms. Even in patients who seem to advocate a surgical approach it is important to heal a dyskinetic puborectalis muscle.
authors.affiliation: Istituto di Clinica Chirurgica Generale, Università degli Studi, Firenze.
authors.forename: M
authors.initials: M
authors.lastname: Nincheri Kunz
authors.forename: F
authors.initials: F
authors.lastname: Renzi
authors.forename: K C
authors.initials: KC
authors.lastname: Kröning
authors.forename: P
authors.initials: P
authors.lastname: Prosperi
authors.forename: A
authors.initials: A
authors.lastname: Giovane
authors.forename: F
authors.initials: F
authors.lastname: Pampaloni
authors.forename: L M
authors.initials: LM
authors.lastname: Pernice
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D012002:Rectal Diseases / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000628:therapy; D012005:Rectal Prolapse / Q000209:etiology; D012007:Rectum / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D014456:Ulcer / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000628:therapy