title: [Light chain deposition disease as a cause of renal failure].
abstract: The objective of the paper is to draw attention to a rare cause of rapidly progressing renal failure which developed in the course of four months as a result of light chain deposition disease. The authors submit two case-histories of the disease assessed by renal biopsy after previous clinical and laboratory suspicion of monoclonal gammapathy. In one patient in the sternal punctate plasmacytoma was diagnosed and in the second case it was not possible to detect any type of monoclonal gammapathy or another possible cause of disease. Renal failure was in both cases irreversible and both patients were enlisted in regular haemodialyzation treatment.
authors.affiliation: Klinika nefrologie a Patologicko-anatomické pracovistĕ IKEM Praha.
authors.forename: P
authors.initials: P
authors.lastname: Wohl
authors.forename: M
authors.initials: M
authors.lastname: Chadimová
authors.forename: M
authors.initials: M
authors.lastname: Englis
authors.forename: P
authors.initials: P
authors.lastname: Táborský
authors.forename: P
authors.initials: P
authors.lastname: Rossmann
authors.forename: I
authors.initials: I
authors.lastname: Matl
mesh_terms: D005260:Female; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000378:metabolism*; D007668:Kidney / Q000276:immunology* / Q000648:ultrastructure; D007674:Kidney Diseases / Q000276:immunology / Q000473:pathology; D008875:Middle Aged; D051437:Renal Insufficiency / Q000276:immunology* / Q000473:pathology