title: [Alveolar hemorrhage in mixed cryoglobulinemia associated with hepatitis C virus infection].
abstract: Alveolar hemorrhage in mixed cryoglobulinemia associated with hepatitis C virus infection. A 61 year-old woman with type II mixed cryoglobulinemia associated to hepatitis C virus infection has suffered alveolar hemorrhage with multiple pulmonary infiltrates, purpura, glomerulonephritis and polyneuropathy. The respiratory and kidney findings resolved with prednisone, but glomerulonephritis reappeared when interferon-alpha treatment was started and prednisone was reduced. This is the third case of alveolar hemorrhage and glomerulonephritis associated with mixed cryoglobulinemia reported in the literature. The lung involvement in mixed cryoglobulinemia is reviewed. The clinic manifestations (asthma, pleural effusion, hemoptysis or pulmonary fibrosis) are uncommon, but the lung involvement is very frequent if roentgenographic signs and necropsy findings are assessed.
authors.affiliation: Servicio de Medicina Interna, Hospital de Llerena, Badajoz.
authors.forename: F F
authors.initials: FF
authors.lastname: Rodríguez-Vidigal
authors.forename: V
authors.initials: V
authors.lastname: Roig Figueroa
authors.forename: E
authors.initials: E
authors.lastname: Pérez-Lucena
authors.forename: V
authors.initials: V
authors.lastname: Ledesma Jurado
authors.forename: P
authors.initials: P
authors.lastname: Ramírez Gurruchaga
authors.forename: F J
authors.initials: FJ
authors.lastname: Aguilar Escobar
authors.forename: M F
authors.initials: MF
authors.lastname: Relea Calatayud
authors.forename: M J
authors.initials: MJ
authors.lastname: Baz
mesh_terms: D019867:Anti-Glomerular Basement Membrane Disease / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001992:Bronchoalveolar Lavage Fluid; D003449:Cryoglobulinemia / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D011650:Pulmonary Alveoli; D013902:Radiography, Thoracic