[Mycoplasma pneumoniae pneumopathy. 10 cases].
OBJECTIVE
Describe the different features of a common disease: Mycoplasma pneumoniae pneumonia.


METHODS
The hospital files of 10 consecutive patients with microbiologically proven Mycoplasma pneumoniae pneumonia were reviewed retrospectively. These 10 patients were hospitalized over a 15-month period among 150 patients admitted to the Versailles general hospital for community-acquired pneumonia. We compared our series with data in the literature.


RESULTS
Most of the patients with Mycoplasma pneumoniae pneumonia were young apparently healthy adults. A bronchial risk factor (smoking, allergy) was however found in 60% of the patients. The principle symptom was persistent cough (100%), with fever and joint pain, or sometimes headache and signs of ENT involvement. Dyspnea was frequent, related more to associated bronchospasticity than to the severity of the pneumonia. Radiographic findings were quite variable. In one case hemolytic anemia and cold agglutinins suggested the diagnosis. Certain diagnosis was based on positive serology after hospitalization due to the long delay between symptom onset and hospitalization. The prehospital period was characterized by a succession of ineffective empirical antibiotic regimens. In routine practice, macrolides or fluoroquinolones administered for 2 to 3 weeks are the empirical antibiotics of choice. Outcome is generally favorable with rapid clinical and radiological improvement. Antibiotic therapy is not however sufficient alone to achieve improvement in the respiratory impairment: bronchodilators and corticosteroids are necessary to treat the bronchospasticity.


CONCLUSIONS
Despite the benign nature of community-acquired pneumonia due to Mycoplasma pneumoniae, clinical manifestations, particularly bronchial inflammation may have important consequences.
Lesobre
V
V
Service de Pneumologie, Centre Hospitalier de Versailles, Le Chesnay.
Azarian
R
R
Gagnadoux
F
F
Harzic
M
M
Pangon
B
B
Petitpretz
P
P
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D006760:Hospitalization; D006801:Humans; D018942:Macrolides; D008297:Male; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification*; D011019:Pneumonia, Mycoplasma / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D015363:Quinolones / Q000627:therapeutic use; D013902:Radiography, Thoracic; D012189:Retrospective Studies; D012307:Risk Factors