Antimicrobial activity of 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid isolated and identified from rice hull.
Two antimicrobial substances in rice hull were isolated and identified as 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid by LC-MS, and 1H- and 13C-NMR. An evaluation of 50% inhibition of growth (IC50) revealed that the two substances had different inhibition profiles against various microorganisms. Most of the gram-positive and some gram-negative bacteria were sensitive to trans 4-hydroxycinnamic acid and 4-hydroxybenzoic acid at IC50 concentrations of 100-170 and 160 micrograms/ml, respectively.
Cho
J Y
JY
Department of Food Science and Technology, Chonnam National University, Kwangju, Korea.
Moon
J H
JH
Seong
K Y
KY
Park
K H
KH
D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D001681:Biological Assay; D003373:Coumaric Acids / Q000302:isolation & purification / Q000494:pharmacology*; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008970:Molecular Weight; D012275:Oryza / Q000737:chemistry*; D010226:Parabens / Q000302:isolation & purification / Q000494:pharmacology*; D011422:Propionates; D013237:Stereoisomerism