New minimal substrate structural requirements in the enzymatic peroxidation of alkenes with soybean lipoxygenase.
A carboxylic or a charged head group in fatty acid analogs is not an essential structural requirement for binding and catalysis in soybean lipoxygenase-1 catalyzed oxidations.
Novak
M J
MJ
Dept. of Experimental Therapeutics, Walter Reed Army Institute of Research, Washington, DC 20307, USA.
D000085:Acetates / Q000737:chemistry / Q000378:metabolism; D000475:Alkenes / Q000737:chemistry* / Q000378:metabolism*; D008084:Lipoxygenase / Q000378:metabolism*; D010084:Oxidation-Reduction; D010545:Peroxides / Q000378:metabolism; D013025:Glycine max / Q000201:enzymology*; D013329:Structure-Activity Relationship; D013379:Substrate Specificity