Survey of genetic screening for oocyte donors.
OBJECTIVE
To describe current screening practices of oocyte donation programs in the Society for Assisted Reproductive Technologies (SART).


METHODS
Descriptive data from a mailed questionnaire.


METHODS
Academic medical center.


METHODS
In vitro fertilization programs in SART.


METHODS
Survey mailed to IVF programs in the SART registry.


METHODS
Current practices, opinions, and genetic criteria for oocyte donor selection.


RESULTS
Results from 159 of 229 (69%) eligible oocyte donation programs are described. Most centers (70%) completed fewer than 25 cycles and used both anonymous and directed donors. There was considerable variability in limits on numbers of cycles or births allowed per donor, with many centers having no limits. As well, the use of well-established screening tests for genetic disorders, such as sickle cell anemia and cystic fibrosis, varied considerably. Consultation with a geneticist was possible at most (89%) centers and specifically mentioned by some centers as a means to help make decisions.


CONCLUSIONS
Most programs follow recommendations made by the American Society of Reproductive Medicine (ASRM) for screening of gamete donors, but a significant percentage does not use well-established testing. The widespread availability of genetic consultation should promote responsible screening practices.
Lewis
V
V
Department of Obstetrics and Gynecology, University of Rochester Medical Center, New York 14642, USA. vivian_lewis@urmc.rochester.edu
Saller
D N
DN
Kouides
R W
RW
Garza
J
J
D005260:Female; D005307:Fertilization in Vitro; D005820:Genetic Testing; D006306:Health Surveys; D006801:Humans; D009865:Oocytes; D011795:Surveys and Questionnaires; D014019:Tissue Donors