Current trends in the detection of antigenaemia, metabolites and cell wall markers for the diagnosis and therapeutic monitoring of fungal infections.
There have been several recent developments in the diagnosis of fungal infections, including the production of novel antigen detection tests, the G-test, and assays for the detection of fungal metabolites. In this article we present an overview of these developments and examine the value of including these tests in clinical trials.
Verweij
P E
PE
Department of Medical Microbiology, University Hospital Nijmegen, The Netherlands.
Poulain
D
D
Obayashi
T
T
Patterson
T F
TF
Denning
D W
DW
Ponton
J
J
D000946:Antigens, Fungal / Q000097:blood* / Q000276:immunology; D001228:Aspergillosis / Q000175:diagnosis*; D002177:Candidiasis / Q000175:diagnosis*; D002986:Clinical Trials as Topic; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005260:Female; D005936:Glucans / Q000097:blood / Q000276:immunology; D006801:Humans; D007159:Immunologic Tests / Q000379:methods*; D007841:Latex Fixation Tests / Q000379:methods; D008297:Male; D008351:Mannans / Q000097:blood / Q000276:immunology; D009181:Mycoses / Q000175:diagnosis*