Hemoglobin-based oxygen carriers: development and clinical potential.
This article addresses issues involved in the development of hemoglobin-based oxygen carriers and provides a focused overview of the 4 hemoglobin-based oxygen carriers with emergency medicine application currently in clinical trials.
Ketcham
E M
EM
School of Medicine, Colorado Emergency Medicine Research Center, University of Colorado Health Sciences Center, Denver, CO, USA.
Cairns
C B
CB
D000818:Animals; D001802:Blood Substitutes / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D018562:Disease Transmission, Infectious / Q000517:prevention & control*; D006454:Hemoglobins / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D065227:Transfusion Reaction
D001802:Blood Substitutes; D006454:Hemoglobins; C016484:hemoglobin, stroma free