[Investigations on the treatment of cerebrospinal nematode infections in goats].
In 17 goats the therapeutical outcome of cerebrospinal nematodiasis, a parasitic infection in the central nervous system with the nematode Elaphostrongylus cervi, is described. The diagnosis was made on the basis of physical findings and cerebrospinal fluid eosinophilia. The therapy was based on the administration of a non-steroidal antiinflammatory drug (flunixin meglumine) and two anthelmintics (fenbendazol, ivermectin) for five days. The response to therapy was documented immediately and 30 days after therapy and by owners report up to 30 months. Eleven goats (64.7%) showed an improvement of the neurological signs directly after therapy. Three had a complete recovery. Signs of a light and middle ataxie were still present in 6 and 2 goats, respectively. Six recumbent goats (35.3%) had to be euthanasied because of a non-therapeutical response. This study has shown a clinical impression of successful use of flunixin meglumine, fenbendazole and ivermectin in goats with light to middle neurological signs. The goats could accommodate the remaining ataxia without showing a reduced production. Goats with high neurological deficits could not be successful treated based on the high degree of the neurological damage.
Departement für Innere Veterinärmedizin, Universität Zürich, Schweiz.
N
N
Pusterla
P
P
Caplazi
H
H
Lutz
U
U
Braun
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D002493:Central Nervous System Diseases / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D003002:Clonixin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005273:Fenbendazole / Q000627:therapeutic use*; D015511:Goat Diseases / Q000188:drug therapy*; D006041:Goats; D007559:Ivermectin / Q000627:therapeutic use*; D008681:Metastrongyloidea; D017206:Strongylida Infections / Q000188:drug therapy / Q000662:veterinary*
D000871:Anthelmintics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D005273:Fenbendazole; D007559:Ivermectin; C014558:flunixin meglumine; D003002:Clonixin