Nitric oxide (NO.) and the nitrosonium cation (NO+) reduce mitochondrial membrane potential and trigger apoptosis in neuronal PC12 cells.
Kayahara
M
M
Weston Laboratory, Hammersmith Hospital, London, UK.
Felderhoff
U
U
Pocock
J
J
Hughes
M N
MN
Mehmet
H
H
D000111:Acetylcysteine / Q000494:pharmacology; D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D016166:Free Radical Scavengers / Q000494:pharmacology; D005978:Glutathione / Q000494:pharmacology; D008564:Membrane Potentials / Q000187:drug effects*; D008928:Mitochondria / Q000187:drug effects* / Q000502:physiology; D009569:Nitric Oxide / Q000494:pharmacology*; D016716:PC12 Cells; D051381:Rats
D016166:Free Radical Scavengers; D009569:Nitric Oxide; D005978:Glutathione; D000111:Acetylcysteine