[The characteristics of the local immune reactions in patients with acute cholecystitis].
Among the investigated 27 gallbladders (GB) using immunofluorescent and histological methods 9 were nonaffected, 7--excised for an acute calculous cholecystitis and 11--for the destructive one. It was established, that the plasmocytes, producing immunoglobulins of main classes, play an important role in the immune defense of the GB mucosa. The stress and hyperfunctioning of the local immune homeostasis mechanisms were revealed in the acute calculous cholecystitis; in the destructive one--the local immune defense disorder, showing the essential lowering of the secretory immunoglobulin A (SIgA) level and the immunocytes-producers IgA quantity, the ratio between plasmocytes and immune complexes, which appear in the vessels wall and perivasal stroma of GB.
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Hnatiuk
D000208:Acute Disease; D000917:Antibody Formation; D002764:Cholecystitis / Q000276:immunology*; D002769:Cholelithiasis / Q000276:immunology; D005704:Gallbladder / Q000276:immunology; D006801:Humans; D018928:Immunity, Mucosal