Polyamine analogue-mediated cell cycle responses in human melanoma cells involves the p53, p21, Rb regulatory pathway.
Kramer
D L
DL
Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
Vujcic
S
S
Diegelman
P
P
White
C
C
Black
J D
JD
Porter
C W
CW
D000123:Acetyltransferases / Q000096:biosynthesis; D017209:Apoptosis / Q000187:drug effects; D002453:Cell Cycle / Q000187:drug effects*; D050759:Cyclin-Dependent Kinase Inhibitor p21; D016213:Cyclins / Q000378:metabolism*; D004790:Enzyme Induction; D006801:Humans; D008545:Melanoma / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D016160:Retinoblastoma Protein / Q000378:metabolism*; D013096:Spermine / Q000031:analogs & derivatives* / Q000494:pharmacology; D014407:Tumor Cells, Cultured; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*; D000099228:Diamine N-Acetyltransferase
D000123:Acetyltransferases; D050759:Cyclin-Dependent Kinase Inhibitor p21; D016213:Cyclins; D016160:Retinoblastoma Protein; D013096:Spermine; D016159:Tumor Suppressor Protein p53; D000099228:Diamine N-Acetyltransferase; C493956:CDKN1A protein, human; C059685:N(1),N(11)-diethylnorspermine