Two similar cases of encephalopathy, possibly a reversible posterior leukoencephalopathy syndrome: serial findings of magnetic resonance imaging, SPECT and angiography.
Two young women who had encephalopathy that resembled reversible posterior leukoencephalopathy syndrome are presented. The brain magnetic resonance imaging (MRI) of these patients exhibited similar T2-high signal lesions, mostly in the white matter of the posterior hemispheres. Xe-SPECT during the patients' symptomatic period showed hypoperfusion in the corresponding areas, and angiography demonstrated irregular narrowing of the posterior cerebral artery. Clinical manifestations subsided soon after treatment, and the abnormal radiological findings also were almost completely resolved. Thus, we concluded that transient hypoperfusion followed by ischemia and cytotoxic edema might have had a pivotal role in these cases.
Department of Neurology, Kushiro Rosai Hospital.
Y
Y
Tajima
K
K
Isonishi
T
T
Kashiwaba
K
K
Tashiro
D000328:Adult; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D001929:Brain Edema / Q000175:diagnosis / Q000209:etiology; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000000981:diagnostic imaging; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D009778:Occipital Lobe / Q000098:blood supply* / Q000000981:diagnostic imaging; D013577:Syndrome; D015899:Tomography, Emission-Computed, Single-Photon
D005343:Fibrinolytic Agents