[Primary manifestation of hepatocellular carcinoma as osteolytic hand metastasis--a case report].
Osseous metastases to the hand are very rare. Only a single case of osseous metastasis of hepatocellular carcinoma to the hand has been reported in the literature to date. We report a case of osteolytic metastasis of the right first metacarpal as first manifestation of unresectable, alpha-fetoprotein-negative hepatocellular carcinoma (pT3, Nx, M1, UICC stage IVB, Okuda's stage I). The therapy consisted of R0-resection and hormonal therapy with tamoxifen 2 x 10 mg/d orally. Generally patients with metastatic cancer to the bones of the hand have a very poor prognosis.
Orthopädische Klinik und Poliklinik, Ludwig-Maximilians-Universität München-Klinikum Grosshadern.
B M
BM
Delsmann
A
A
Lienemann
A
A
Nerlich
E
E
Hoffmann
W H
WH
Caselmann
H J
HJ
Refior
D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D008663:Metacarpus / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009367:Neoplasm Staging; D010014:Osteolysis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery