Primary nonsecretory plasma cell leukemia: a rare variant of multiple myeloma.
We report a patient with primary nonsecretory plasma cell leukemia. These cells resembled prolymphocytes and expressed only CD38 and CD56. Due to the atypical morphology and lack of monoclonal immunoglobulins in both serum and urine, it was difficult to make a correct diagnosis. Electron-microscopic and immunocytochemical cytoplasmic studies were useful.
Kawada
E
E
Department of Internal Medicine, Fujioka General Hospital, Gunma, Japan.
Shinonome
S
S
Saitoh
T
T
Tamura
J
J
Karasawa
M
M
Sawamura
M
M
Murakami
H
H
D000368:Aged; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D007952:Leukemia, Plasma Cell / Q000175:diagnosis* / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron