[The effect of insulin therapy on erythrocyte insulin receptor activity in patients with terminal kidney failure].
Levels of insulin-carrying erythrocytes (ICE) were studied in 30 patients as was a concentration of immunoreactive insulin in 36 patients with chronic renal insufficiency in pre- and postdialysis period as well as after insulinization. A decrease in ICE counts was noted in patients as compared with donors. In the prehemodialysis period, 38.8 percent of the examined patients revealed hyperinsulinemia that during the process of hemodialysis returned to normal, having become attenuated in some cases to hypoinsulinemia values. Insulinization in anabolic dosages made for improvement in metabolism and insulin receptor activity of erythrocytes.
Tychka
I B
IB
Zahraĭ
L B
LB
D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D006946:Hyperinsulinism / Q000097:blood / Q000628:therapy; D007328:Insulin / Q000627:therapeutic use*; D007330:Insulin Antibodies / Q000097:blood; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000628:therapy*; D011972:Receptor, Insulin / Q000097:blood / Q000187:drug effects*; D006435:Renal Dialysis; D013997:Time Factors
D007328:Insulin; D007330:Insulin Antibodies; D011972:Receptor, Insulin