Peripheral T cell lymphoma in a patient with common variable immunodeficiency disease: case report and literature review.
This report documents the occurrence of a peripheral T cell lymphoma arising in the bone marrow and liver of a patient with common variable immunodeficiency disease. The T cell origin of this lymphoma was demonstrated by immunohistochemical phenotyping and gene rearrangement studies and was not associated with EBV infection of the lymphoma cells. The frequency and characteristics of lymphomas complicating CVID are reviewed.
Department of Pathology, SUNY Health Science Center at Brooklyn, NY 11203, USA.
S R
SR
Gottesman
D
D
Haas
M
M
Ladanyi
E L
EL
Amorosi
D000328:Adult; D017074:Common Variable Immunodeficiency / Q000150:complications / Q000235:genetics / Q000473:pathology; D005260:Female; D006801:Humans; D016411:Lymphoma, T-Cell, Peripheral / Q000209:etiology / Q000235:genetics / Q000473:pathology