Nonoperative treatment of Dupuytren's disease.
Many nonoperative therapies have been investigated for the treatment of Dupuytren's disease. These include needle fasciotomy, continuous slow skeletal traction, radiation, dimethyl sulfoxide, vitamin E, allopurinol, physical therapy, ultrasound therapy, steroid injections, radiation, interferon, splinting, and enzymatic fasciotomy. Most of these therapies have not proven to be clinically useful. However, recent investigation of enzymatic fasciotomy using collagenase injection has shown encouraging results.
Department of Orthopaedics, Health Science Center, State University of New York at Stony Brook, USA.
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Hurst
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Badalamente
D017364:Collagenases / Q000627:therapeutic use; D004387:Dupuytren Contracture / Q000000981:diagnostic imaging / Q000628:therapy*; D000071938:Fasciotomy; D006801:Humans; D008662:Metacarpophalangeal Joint / Q000000981:diagnostic imaging; D014463:Ultrasonography
D017364:Collagenases