Comparative characteristics of the Israeli Newcastle disease virus field strains by means of a wide panel of monoclonal antibodies against hemagglutinin-neuraminidase glycoprotein.
Fourteen mouse monoclonal antibodies (MAB) were tested for their ability to react with 15 reference and 52 local Newcastle disease virus (NDV) strains isolated in Israel during the last decade from feral birds. All the field isolates had no antigenic difference when examined by classic serological tests. However, MAB-mediated analysis revealed wide antigenic heterogeneity amongst the studied viruses. By the pattern of the MAB reactivity, all the isolates could be distributed into 13 groups.
Division of Avian Diseases, Kimron Veterinary Institute, Beit Dagan, Israel.
A
A
Panshin
E
E
Shihmanter
Y
Y
Weisman
C
C
Orvell
M
M
Lipkind
D000818:Animals; D000835:Animals, Wild; D000911:Antibodies, Monoclonal / Q000276:immunology*; D001717:Birds; D002645:Chickens; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D000939:Epitopes; D015707:HN Protein / Q000276:immunology*; D006386:Hemagglutination Tests / Q000662:veterinary; D005779:Immunodiffusion / Q000662:veterinary; D007557:Israel; D051379:Mice; D009521:Newcastle Disease / Q000821:virology*; D009522:Newcastle disease virus / Q000145:classification* / Q000276:immunology / Q000472:pathogenicity; D015531:Radioimmunoprecipitation Assay / Q000662:veterinary
D000911:Antibodies, Monoclonal; D000939:Epitopes; D015707:HN Protein