Corneal topography in asymptomatic family members of a patient with pellucid marginal degeneration.
OBJECTIVE
To report corneal topographic patterns in asymptomatic family members of a patient with pellucid marginal degeneration.


METHODS
Computer-assisted corneal topography was used to study the corneas of five family members of a patient with pellucid marginal degeneration.


RESULTS
In all five asymptomatic family members, corneal biomicroscopy was normal. Corneal topography, however, showed various abnormalities in different members of this family, particularly a topographic pattern suggesting keratoconus in one family member and a topographic pattern suggesting pellucid marginal degeneration in another family member.


CONCLUSIONS
This study reinforces the hypothesis that corneal ectatic disorders may represent different manifestations of a clinical spectrum.
Department of Ophthalmology, University of São Paulo, School of Medicine, Brazil. sjbechar@usp.br
R M
RM
Santo
S J
SJ
Bechara
N
N
Kara-José
D000328:Adult; D000368:Aged; D003315:Cornea / Q000473:pathology*; D003317:Corneal Dystrophies, Hereditary / Q000473:pathology*; D019781:Corneal Topography; D005190:Family; D005260:Female; D006801:Humans; D008297:Male; D010375:Pedigree