Studies on novel 3-isoxazolylvinyl-cephalosporins: II. Synthesis and biological activity of 7-[2-(2-aminothiazol-4-yl)-2-hydroxy-iminoacetamido] derivatives.
Choi
K I
KI
Biochemical Research Center, Korea Institute of Science and Technology, Seoul.
Cha
J H
JH
Pae
A N
AN
Cho
Y S
YS
Kim
Y
Y
Chang
M H
MH
Park
S H
SH
Park
S Y
SY
Kim
D
D
Jeong
D Y
DY
Kim
Y H
YH
Kong
J Y
JY
Koh
H Y
HY
D000818:Animals; D000077525:Cefdinir; D015296:Ceftizoxime / Q000031:analogs & derivatives / Q000494:pharmacology; D002511:Cephalosporins / Q000138:chemical synthesis* / Q000493:pharmacokinetics / Q000494:pharmacology*; D006094:Gram-Positive Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D016106:Methicillin Resistance; D051379:Mice; D008813:Mice, Inbred ICR; D015394:Molecular Structure; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship; D014640:Vancomycin / Q000494:pharmacology; D000097623:Cefpodoxime
D000077525:Cefdinir; D015296:Ceftizoxime; D002511:Cephalosporins; D014640:Vancomycin; D000097623:Cefpodoxime; C117834:7-((2-aminothiazol-4-yl)-2-(N-hydroxyimino)acetamido)-3-((3-methoxyisoxazol-5-yl)ethenyl)cephalosporanic acid; C117835:7-((2-aminothiazol-4-yl)-2--(N-hydroxyimino)acetamido)-3-((3-chloroisoxazol-5-yl)ethenyl)cyclosporanic acid