Phage-display technology--finding a needle in a vast molecular haystack.
Screening of phage-displayed libraries of proteins and peptides has, for nearly a decade, proven to be a highly effective method for finding much needed 'needles' in a vast molecular 'haystack'. Over the past year, it has been used to solve an increasing diversity of problems, including identification of binding motifs for much smaller targets and the use of novel screening methods to identify chemical activities.
Rodi
D J
DJ
Institute of Molecular Biophysics Florida State University Tallahassee Florida 32306 USA.
Makowski
L
L
D017104:Bacteriophage M13 / Q000502:physiology*; D001435:Bacteriophages / Q000235:genetics*; D001709:Biotechnology / Q000379:methods*; D003626:Data Display; D015723:Gene Library; D008958:Models, Molecular; D018716:Molecular Mimicry; D019151:Peptide Library; D014764:Viral Proteins / Q000096:biosynthesis / Q000235:genetics; D014779:Virus Replication
D019151:Peptide Library; D014764:Viral Proteins