Acral dermatofibrosarcoma protuberans with metastases.
Dermatofibrosarcoma protuberans (DFSP) is an uncommon cutaneous tumor that occurs rarely on the extremities. This tumor has a particular propensity for local recurrence following seemingly adequate excision. Metastases are rare, and usually follow repeated local recurrences. On rare occasions, fibrosarcomatous change may arise in a DFSP, and appears to affect adversely the prognosis. The adequacy of the initial resection is the most important prognostic factor; however, suggested margins vary between 1.5 and 5 cm. The ideal margin of resection on the foot is unknown. We report a patient with recurrent, acral DFSP with fibrosarcomatous change and pulmonary parenchymal metastases in a 48-year-old black male.
Skoll
P J
PJ
Department of Anatomical Pathology, Groote Schuur Hospital, and the University of Cape Town, South Africa.
Hudson
D A
DA
Taylor
D A
DA
D018223:Dermatofibrosarcoma / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D005534:Foot Diseases / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery