[Management of breast cancer in geriatric age; observations on 164 cases].
Progressive increasing of the life expectancy and the ever more frequent finding of breast cancer in elderly women have focused the attention on the treatment of this pathology in the elderly women. Today most studies support a more aggressive locoregional and systemic therapy in older patients in good physical condition. Authors analyze retrospectively a series of 164 women with breast cancer aged over 69 years treated with combined modality therapy regarding the stage of disease and the status of the patient. Survival by stage, tumor characteristics, node involvement have been compared with a series of patients less than 70 years treated on the same period. Survival curves were not significantly different between the two groups, except for T1 which showed a better survival in younger patients. Also survival according to node involvement did not show significant differences between the two groups. in conclusion, older women should be treated with the same surgical procedures, according to stage, of the younger patients, if they are not too frail to undergo surgery. Only the definitive results of prospective randomized trials will better define the indications and limits of a further reduction of the extent of surgical excision.
Roseano
M
M
Istituto di Clinica Chirurgica Generale e Terapia Chirurgica, Università degli studi di Trieste.
Calligaris
L
L
Eramo
R
R
Sandri
P
P
Bortul
M
M
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006304:Health Status; D006801:Humans; D008408:Mastectomy / Q000379:methods*; D015412:Mastectomy, Segmental; D015996:Survival Rate; D016896:Treatment Outcome