[The characteristics of the metabolic changes in patients with bronchopulmonary diseases undergoing the use of extracorporeal detoxification methods].
A comparative analysis was done of certain metabolic changes in patients with chronic obstructive bronchitis in the phase of exacerbation before and after plasmapheresis. Plasmapheresis was found out to make for lowering of the level of medium-size molecules of peptides, as well as for decrease in acute-phase proteins (ceruloplasmin, transferrin), restoration of equilibrium in the system of proteinases-inhibitors of proteinases, and enhancement of lipid peroxidation processes. The results obtained suggest expediency of employment of drugs endowed with an antioxidant activity in application of the extracorporeal methods of detoxification.
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D000328:Adult; D001991:Bronchitis / Q000097:blood* / Q000628:therapy*; D002908:Chronic Disease; D006801:Humans; D015227:Lipid Peroxidation; D008875:Middle Aged; D010956:Plasmapheresis / Q000706:statistics & numerical data