A retrospective cohort study of male workers exposed to PVA fibers.
In order to ascertain whether PVA fibers can produce cancer in humans or not, we have conducted a retrospective cohort study of workers exposed to PVA fibers. A total of 447 exposed and 2416 non-exposed male workers who were engaged before 1980 were followed up until the end of 1996. The SMR for all causes was 0.57 (observed 38, 95% CI: 0.41-0.78) for the exposed, and 0.66 (observed 210, 95% CI: 0.58-0.75). As for lung cancer, its SMR was 0.77 (observed 3, 95% CI: 0.15-2.24) for the exposed workers and 0.67 (12 observed, 95% CI: 0.34-1.16) for the non-exposed workers. Lung cancer SMR was 0.86 (observed 2, 95% CI: 0.10-3.11) for the workers with 20 or more years' employment. This study showed no difference in lung cancer risk between the workers exposed to PVA fibers and the non-exposed workers.
Department of Epidemiology and Field Research, Osaka Medical Center for Cancer & Cardiovascular Diseases, Japan.
K
K
Morinaga
K
K
Nakamura
N
N
Kohyama
T
T
Kishimoto
D000328:Adult; D000368:Aged; D002423:Cause of Death; D015331:Cohort Studies; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D011142:Polyvinyl Alcohol / Q000009:adverse effects*; D012189:Retrospective Studies; D018570:Risk Assessment
D011142:Polyvinyl Alcohol