Induction of sister chromatid exchanges and chromosome aberrations in vivo in Etroplus suratensis (Bloch) following exposure to organophosphorus pesticides.
The genotoxic potential of methyl parathion and phosphamidon, two commercial formulations of organophosphorus pesticides, was evaluated through induction of sister chromatid exchanges (SCE) and chromosome aberrations in fish gill tissues. Fishes exposed to the medium containing 0.05, 0.1 and 0.2 ppm of methyl parathion or 0.5, 1.0, and 2.0 ppm of phosphamidon for a duration of 96 h revealed significant increase in the number of SCE and chromosome aberrations against control values. This demonstrates the feasibility of the fish in vivo system in detecting genotoxic potential of pollutants.
Central Marine Fisheries Research Institute, Cochin, India. pdas@nii.ernet.in
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P
Das
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G
John
D000818:Animals; D002869:Chromosome Aberrations / Q000235:genetics*; D005880:Gills / Q000166:cytology / Q000187:drug effects; D007306:Insecticides / Q000633:toxicity*; D007621:Karyotyping; D008677:Metaphase / Q000187:drug effects; D008743:Methyl Parathion / Q000633:toxicity; D010471:Perches / Q000502:physiology*; D010707:Phosphamidon / Q000633:toxicity; D012854:Sister Chromatid Exchange / Q000187:drug effects*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
D007306:Insecticides; D014874:Water Pollutants, Chemical; D010707:Phosphamidon; D008743:Methyl Parathion