Stress proteins and immunity mediated by cytotoxic T lymphocytes.
Chaperone molecules, including members of the heat shock protein family, are able to stimulate alphabeta and gammadelta T cells as well as natural killer cells. For alphabeta T cells, specificity is induced by chaperone-assisted peptides; this has lead to detailed investigations of peptides that bind to these chaperones and their possible role in antigen presentation.
Schild
H
H
Department of Immunology, Institute for Cell Biology, University of Tübingen, Germany.
Arnold-Schild
D
D
Lammert
E
E
Rammensee
H G
HG
D006360:Heat-Shock Proteins / Q000276:immunology*; D006801:Humans; D007109:Immunity; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*
D006360:Heat-Shock Proteins