Clinical and serological analysis of a Q fever outbreak in western Slovakia with four-year follow-up.
In the spring of 1993, an outbreak of respiratory infection affected 113 persons (103 males) in Jedl'ové Kostol'any, a village located in a hilly area of western Slovakia. Q fever, manifested as a flu-like illness with atypical pneumonia and hepatic involvement, was diagnosed using four serological tests (microimmunofluorescence, microagglutination, complement fixation, and enzyme immunoassay). Aborting goats were proven as a source of infection. During a 4-year follow-up study, no chronic form of Q fever could be demonstrated, either clinically or by tests to detect phase I Coxiella burnetii antibodies.
Kovácová
E
E
Institute of Virology, Slovak Academy of Sciences, Bratislava. virukova@savba.sk
Kazár
J
J
Simková
A
A
D000034:Abortion, Veterinary / Q000382:microbiology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D016997:Coxiella burnetii / Q000276:immunology / Q000302:isolation & purification*; D004196:Disease Outbreaks; D005260:Female; D005500:Follow-Up Studies; D015511:Goat Diseases / Q000382:microbiology; D006041:Goats; D006801:Humans; D008297:Male; D051379:Mice; D011247:Pregnancy; D011778:Q Fever / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D012698:Serologic Tests; D018154:Slovakia / Q000453:epidemiology; D015047:Zoonoses / Q000453:epidemiology*
D000907:Antibodies, Bacterial