Bartonella henselae infection associated with peripapillary angioma, branch retinal artery occlusion, and severe vision loss.
OBJECTIVE
To report atypical clinical features of Bartonella henselae neuroretinitis treated with combination antibiotics.


METHODS
Case report.


RESULTS
A 20-year-old man with a positive B. henselae titer developed a unilateral neuroretinitis, a large peripapillary angiomatous lesion, branch artery occlusion with ischemic maculopathy, and vision loss that failed to improve with clindamycin. Treatment with doxycycline and rifampin led to rapid clinical improvement. The severe vision loss in this case is atypical.


CONCLUSIONS
Ocular findings associated with B. henselae infection may include retinal angiomatous lesion and branch retinal artery occlusion. Doxycycline and rifampin were successful in treating the infection.
Gray
A V
AV
Department of Ophthalmology, University of California, Davis, Sacramento 95817, USA.
Reed
J B
JB
Wendel
R T
RT
Morse
L S
LS
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D018416:Bartonella henselae / Q000276:immunology; D001766:Blindness / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D002372:Cat-Scratch Disease / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D004318:Doxycycline / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004797:Enzyme-Linked Immunosorbent Assay; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D018324:Hemangioma, Capillary / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008297:Male; D009902:Optic Neuritis / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D015356:Retinal Artery Occlusion / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D019572:Retinal Neoplasms / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology; D012173:Retinitis / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D012293:Rifampin / Q000627:therapeutic use; D014792:Visual Acuity
D000907:Antibodies, Bacterial; D004318:Doxycycline; D012293:Rifampin