Antimicrobial prophylaxis in colorectal surgery.
This article summarises the findings of a systematic review of the literature concerning antimicrobial prophylaxis before colorectal surgery. From analysing 152 clinical trials certain conclusions can be drawn, such as the importance of ensuring that prophylactic therapy is active against both aerobic and anaerobic bacteria; and, single dose treatment can be as effective as a full course of antibiotics.
Glenny
A M
AM
NHS Centre for Reviews and Dissemination, University of York.
Song
F
F
D019072:Antibiotic Prophylaxis / Q000379:methods*; D003108:Colonic Diseases / Q000601:surgery*; D004334:Drug Administration Schedule; D006801:Humans; D012002:Rectal Diseases / Q000601:surgery*; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000209:etiology / Q000517:prevention & control*; D016896:Treatment Outcome