An unusual case of Lafora body disease.
A case is described in which non-convulsive status epilepticus (NCSE) prompted further investigation leading to the diagnosis of Lafora body disease (LBD). The onset of NCSE was temporally related to the withdrawal of sodium valproate and introduction of carbamazepine, which may have been precipitating factors. NCSE has not previously been reported in LBD. Implications for its drug management are discussed.
Corkill
R G
RG
Magnetic Resonance Spectroscopy Unit, John Radcliffe Hospital, Oxford OX3 9DU, UK.
Hardie
R J
RJ
D000293:Adolescent; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology; D004569:Electroencephalography; D017809:Fatal Outcome; D006801:Humans; D020192:Lafora Disease / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D013226:Status Epilepticus / Q000188:drug therapy*; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D014635:Valproic Acid