Surface protein adhesins of Staphylococcus aureus.
Staphylococcus aureus can colonize the host to initiate infection by adhering to components of the extracellular matrix. Adherence is mediated by surface protein adhesins (MSCRAMMs). Ligand binding by these fibronectin-, fibrinogen- and collagen-binding proteins occurs by distinct mechanisms that are being investigated at the molecular level.
Microbiology Dept, Moyne Institute of Preventive Medicine, Trinity College, Dublin, Ireland. tfoster@tcd.ie
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Foster
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Höök
D018829:Adhesins, Bacterial / Q000378:metabolism*; D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism; D003094:Collagen / Q000378:metabolism; D005353:Fibronectins / Q000378:metabolism; D006801:Humans; D028044:Phosphate-Binding Proteins; D013211:Staphylococcus aureus / Q000502:physiology*
D018829:Adhesins, Bacterial; D001426:Bacterial Proteins; C112303:CAVIN2 protein, human; D002352:Carrier Proteins; D005353:Fibronectins; D028044:Phosphate-Binding Proteins; C048165:adhesin, Staphylococcus aureus; D003094:Collagen