Comparison of Zeeman Background Corrected Atomic Absorption Spectrometric and Inductively Coupled Plasma Mass Spectrometric detection of trace elements in electrothermally vaporized serum.
There is continued interest in the measurement of degradation products of metallic implants in biological tissues and fluids. A study was conducted to compare analytical results obtained by the Zeeman Background Corrected Atomic Absorption Spectrometric and Inductively Coupled Plasma Mass Spectrometric techniques on a uniform set of triple-element (Ti, Al, and V) spiked human serum specimens over concentration ranges up to 20 ppb (20 ng/ml). The results indicate that the two methods are comparable. The positive and negative aspects of each method of instrumental analysis are discussed.
Department of Orthopaedic Surgery, Rush Presbyterian St. Lukes Medical Center, Chicago, Illinois, USA. askipor@rush.edu
A K
AK
Skipor
J J
JJ
Jacobs
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L
Yu
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Black
D001672:Biocompatible Materials; D001673:Biodegradation, Environmental; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods; D008670:Metals; D019736:Prostheses and Implants; D012044:Regression Analysis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013054:Spectrophotometry, Atomic / Q000379:methods; D014131:Trace Elements / Q000097:blood*
D001672:Biocompatible Materials; D008670:Metals; D014131:Trace Elements