Fluorescein and indocyanine green angiographic findings in congenital optic disk pit associated with macular detachment.
OBJECTIVE
To investigate the pattern of congenital optic disk pits associated with maculopathy using indocyanine green angiography (ICG) and fluorescein angiography (FA).


METHODS
Seventeen consecutive patients with unilateral congenital optic disk pit complicated by maculopathy were prospectively enrolled in the study. Complete ophthalmologic examination, color stereophotography, red-free photography, FA, and ICG angiography were performed on all patients during their first examination in our department.


RESULTS
Absolute hypofluorescence of the optic disk pit was noted in all eyes on ICG angiography. On the contrary, all eyes showed early hypofluorescence and late staining of the optic pit on FA. All 17 eyes presented a delineated late hyperfluorescence corresponding to the area of macular elevation on both ICG angiography and FA. The intensity of the hyperfluorescence was milder in cases with long-standing maculopathy.


CONCLUSIONS
Imaging of congenital optic disk pits associated or not with macular elevation using ICG angiography has not been reported in the literature. The increased hyperfluorescence in the late phases of the macular elevation in the studied eyes could be attributed to leakage of indocyanine or fluorescein dye into the schisis cavity and the subretinal fluid.
Theodossiadis
G P
GP
Department of Ophthalmology, Athens University School of Medicine, General Hospital of Athens, Greece.
Ladas
I D
ID
Panagiotidis
D N
DN
Kollia
A C
AC
Voudouri
A N
AN
Theodossiadis
P G
PG
D000293:Adolescent; D000328:Adult; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D009898:Optic Disk / Q000002:abnormalities* / Q000098:blood supply / Q000473:pathology; D009901:Optic Nerve Diseases / Q000150:complications* / Q000151:congenital*; D011446:Prospective Studies; D012163:Retinal Detachment / Q000150:complications* / Q000473:pathology; D014792:Visual Acuity
D007208:Indocyanine Green