Tumour necrosis factor induced autophagy and mitochondrial morphological abnormalities are mediated by TNFR-I and/or TNFR-II and do not invariably lead to cell death.
Department of Medicine, University of Cambridge, U.K.
J
J
Prins
E
E
Ledgerwood
P
P
Ameloot
P
P
Vandenabeele
P
P
Faraco
N
N
Bright
S
S
O'Rahilly
J
J
Bradley
D016475:3T3 Cells; D017667:Adipocytes / Q000187:drug effects / Q000648:ultrastructure; D000818:Animals; D015703:Antigens, CD / Q000502:physiology*; D017209:Apoptosis / Q000187:drug effects*; D001343:Autophagy / Q000187:drug effects*; D002478:Cells, Cultured; D006801:Humans; D051379:Mice; D008928:Mitochondria / Q000187:drug effects*; D018124:Receptors, Tumor Necrosis Factor / Q000502:physiology*; D047888:Receptors, Tumor Necrosis Factor, Type I; D047889:Receptors, Tumor Necrosis Factor, Type II; D015398:Signal Transduction; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology*
D015703:Antigens, CD; D018124:Receptors, Tumor Necrosis Factor; D047888:Receptors, Tumor Necrosis Factor, Type I; D047889:Receptors, Tumor Necrosis Factor, Type II; D014409:Tumor Necrosis Factor-alpha