Optic nerve hypoplasia with posterior pituitary ectopia: male predominance and nonassociation with breech delivery.
OBJECTIVE
To determine whether posterior pituitary ectopia in children with optic nerve hypoplasia has a male predominance or an increased incidence of breech delivery.


METHODS
Retrospective analysis of 12 children with optic nerve hypoplasia and posterior pituitary ectopia.


RESULTS
Eleven of 12 patients with posterior pituitary ectopia were boys. No child had a history of breech delivery. Two children had a history of breech positioning but were delivered by cesarean section.


CONCLUSIONS
Posterior pituitary ectopia with optic nerve hypoplasia shows a strong male predominance but no association with breech delivery.
University of Arkansas for Medical Sciences, Little Rock, USA.
M C
MC
Brodsky
D000293:Adolescent; D000328:Adult; D001131:Arkansas / Q000453:epidemiology; D001946:Breech Presentation; D002648:Child; D002675:Child, Preschool; D005260:Female; D013006:Growth Hormone / Q000172:deficiency; D006801:Humans; D007018:Hypopituitarism / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D009900:Optic Nerve / Q000002:abnormalities* / Q000473:pathology; D010904:Pituitary Gland, Posterior / Q000002:abnormalities* / Q000473:pathology; D010908:Pituitary Hormones, Anterior / Q000172:deficiency; D011247:Pregnancy; D012189:Retrospective Studies; D017678:Sex Distribution
D010908:Pituitary Hormones, Anterior; D013006:Growth Hormone