[Comparative assessment of contractility of different sections of the intestine (an experimental study)].
Contractility of different portions of the intestine used for partial or complete replacement of the bladder was studied on the circular fragments of non-inbred rats' intestine. The contractility was studied at rest, in response to electric stimulation, addition to the solution of growing concentrations of cholinomimetic or adrenomimetic drugs, to depolarization of smooth cell membrane with hypersodium solution. It was established that contractility of the large intestine contrary to that of the small intestine is characterized by diminished amplitude of spontaneous contractions. In addition of cholino- and adrenomimetics, amplitude of the phasic and tonic reactions in the large intestine fragments compared to those of the small one was decreased. The conclusion was made that the large intestine is preferable for taking transplants partially replacing urinary bladder to correct its reservoir function whereas small intestinal grafts are more suitable for total replacement of the detrusor.
Loran
O B
OB
Kirpatovskiĭ
V I
VI
Mudraia
I S
IS
Zaĭtsev
A V
AV
David'iants
A A
AA
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D004558:Electric Stimulation; D004837:Epinephrine / Q000494:pharmacology; D005260:Female; D066298:In Vitro Techniques; D007420:Intestine, Large / Q000187:drug effects / Q000502:physiology / Q000637:transplantation; D007421:Intestine, Small / Q000187:drug effects / Q000502:physiology / Q000637:transplantation; D007422:Intestines / Q000187:drug effects / Q000502:physiology* / Q000637:transplantation*; D007552:Isotonic Solutions; D008297:Male; D008954:Models, Biological; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology*; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D001743:Urinary Bladder / Q000601:surgery*
D007552:Isotonic Solutions; C051865:Krebs-Ringer solution; D000109:Acetylcholine; D004837:Epinephrine