Warfarin prophylaxis after total knee arthroplasty.
Low-dose warfarin prophylaxis has been found to provide safe and effective prophylaxis after TKA. The major advantage of warfarin prophylaxis is that it can be administered orally. However, monitoring of the INR level is required, and there are concerns that TKA patients may be relatively unprotected during the early perioperative period. In addition, further analysis of the impact of asymptomatic clot formation on venous stasis disease is required. Our protocol is to administer 2 weeks of DVT prophylaxis after TKA. Routine screening with ultrasonography is not recommended at this time.
Lieberman
J R
JR
Department of Orthopedic Surgery, UCLA Medical Center, Los Angeles, California 90024-3010, USA.
D000925:Anticoagulants / Q000008:administration & dosage* / Q000191:economics; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects; D002986:Clinical Trials as Topic; D003362:Cost-Benefit Analysis; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D006801:Humans; D007902:Length of Stay; D011182:Postoperative Care / Q000191:economics; D011379:Prognosis; D013923:Thromboembolism / Q000209:etiology / Q000517:prevention & control*; D016896:Treatment Outcome; D014859:Warfarin / Q000008:administration & dosage* / Q000191:economics
D000925:Anticoagulants; D014859:Warfarin