Studies on novel 3-isoxazolylvinyl-cephalosporins: I. Synthesis and biological activity of 7-[2-(2-aminothiazol-4-yl)-2-(alkoxy)-iminoacetamido] derivatives.
Choi
K I
KI
Biochemicals Research Center, Korea Institute of Science and Technology, Seoul.
Cha
J H
JH
Pae
A N
AN
Cho
Y S
YS
Chang
M H
MH
Koh
H Y
HY
D000818:Animals; D002511:Cephalosporins / Q000138:chemical synthesis* / Q000493:pharmacokinetics / Q000494:pharmacology*; D015195:Drug Design; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D013329:Structure-Activity Relationship
C117833:3-((3-(1-acetoxyethyl)isoxazol-5-yl)ethenyl)-7-((2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)cephalosporanic acid; D002511:Cephalosporins