Action at the ends of microtubules.
Microtubule-based motility in the cell is directly associated with changes in microtubule numbers through nucleation and growth and shrinkage of the polymer from the ends. Recent analysis of spindle pole bodies and kinetochores in yeast reveal how the cell builds specialized structures for association with the ends of microtubules.
Department of Biological Sciences 258 Crawford Hall University of Pittsburgh Pittsburgh PA 15260 USA. wsaund+@pitt.edu
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Saunders
D002503:Centromere / Q000378:metabolism; D018385:Centrosome / Q000502:physiology; D018386:Kinetochores / Q000378:metabolism; D008870:Microtubules / Q000502:physiology*; D012441:Saccharomyces cerevisiae / Q000502:physiology*; D012568:Schizosaccharomyces / Q000502:physiology*; D015398:Signal Transduction; D008941:Spindle Apparatus / Q000502:physiology