Gliclazide.
The crystal structure of gliclazide, N-[(perhydrocyclopenta [c]pyrrol-2-yl)aminocarbonyl]-p-toluenesulfonamide, C15H21B3O3S, a second-generation oral hypoglycemic agent, contains discrete molecules with normal molecular dimensions. Both of the five-membered fused rings adopt envelope conformations. The molecules are linked into chains by intermolecular hydrogen bonds involving amino-H atoms, with N...O separations of 2.967 (3) and 2.949 (3) A.
Parvez
M
M
Department of Chemistry, University of Calgary, Alberta, Canada. parvez@acs.ucalgary.ca
Arayne
M S
MS
Zaman
M K
MK
Sultana
N
N
D018360:Crystallography, X-Ray; D005907:Gliclazide / Q000737:chemistry*; D007004:Hypoglycemic Agents / Q000737:chemistry*; D015394:Molecular Structure
D007004:Hypoglycemic Agents; D005907:Gliclazide