Effect of shellfish calcium on the apparent absorption of calcium and bone metabolism in ovariectomized rats.
Fossil shellfish powder (FS) and Ezo giant scallop shell powder (EG) were rendered soluble with lactate and citrate under decompression (FSEx and EGEx, respectively) and we examined the effects of lactate-citrate solubilization of FS and EG on mineral absorption, tissue mineral contents, serum biochemical indices and bone mineral density (BMD) in ovariectomized (OVX) rats. The apparent absorption ratios of minerals tended to be high in the rats fed with the solubilized mineral sources, those in the FSEx group being significantly higher than in the FS group. There was no significant difference in the tibia mineral content among the OVX groups. BMD at the distal femoral diaphysis was significantly increased by FSEx and EGEx feeding. It is suggested that solubilization with lactate and citrate under decompression increased the solubility and bioavailability of calcium from such natural sources of shellfish calcium as FS and EG.
Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
T
T
Miura
Y
Y
Takayama
M
M
Nakano
D000818:Animals; D015519:Bone Density / Q000187:drug effects; D001842:Bone and Bones / Q000187:drug effects / Q000378:metabolism*; D002136:Calcium, Dietary / Q000008:administration & dosage / Q000302:isolation & purification / Q000493:pharmacokinetics*; D019343:Citric Acid; D005260:Female; D007408:Intestinal Absorption; D019344:Lactic Acid; D010052:Ovariectomy; D010053:Ovary / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D012758:Shellfish; D012995:Solubility
D002136:Calcium, Dietary; D019343:Citric Acid; D019344:Lactic Acid