Stress proteins and immunity mediated by cytotoxic T lymphocytes.
Chaperone molecules, including members of the heat shock protein family, are able to stimulate alphabeta and gammadelta T cells as well as natural killer cells. For alphabeta T cells, specificity is induced by chaperone-assisted peptides; this has lead to detailed investigations of peptides that bind to these chaperones and their possible role in antigen presentation.
Department of Immunology, Institute for Cell Biology, University of Tübingen, Germany.
H
H
Schild
D
D
Arnold-Schild
E
E
Lammert
H G
HG
Rammensee
D006360:Heat-Shock Proteins / Q000276:immunology*; D006801:Humans; D007109:Immunity; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*
D006360:Heat-Shock Proteins