Maple syrup urine disease metabolites induce apoptosis in neural cells without cytochrome c release or changes in mitochondrial membrane potential.
Weston Laboratory, Imperial College of Science, Technology and Medicine, Hammersmith Hospital, London, UK.
P
P
Jouvet
P
P
Rustin
U
U
Felderhoff
J
J
Pocock
U
U
Joashi
N D
ND
Mazarakis
C
C
Sarraf
A D
AD
Edwards
H
H
Mehmet
D017209:Apoptosis; D003574:Cytochrome c Group / Q000378:metabolism*; D006801:Humans; D008375:Maple Syrup Urine Disease / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D008564:Membrane Potentials; D008928:Mitochondria / Q000201:enzymology / Q000502:physiology*; D009474:Neurons / Q000473:pathology*
D003574:Cytochrome c Group