The kidney as part of the cardiovascular system.
Renal vascular damage caused by arterial hypertension brings about changes in the systemic vascular function and structure. Nephrosclerosis appears to run in parallel with systemic atherosclerosis, accounting for the increased cardiovascular morbidity and mortality in hypertensive patients. Parameters indicating a change in renal function (increased serum creatinine concentration, proteinuria, and microalbuminuria) are independent predictors of increased cardiovascular morbidity and mortality and must therefore be considered in the classification of cardiovascular risk in hypertensive patients.
Ruilope
L M
LM
Hypertension Unit, Hospital 12 de Octubre, Madrid, Spain.
D000419:Albuminuria; D001161:Arteriosclerosis / Q000150:complications*; D002318:Cardiovascular Diseases / Q000209:etiology*; D003404:Creatinine / Q000097:blood; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000517:prevention & control; D007674:Kidney Diseases / Q000150:complications / Q000209:etiology*; D009400:Nephrosclerosis / Q000209:etiology* / Q000401:mortality; D011507:Proteinuria; D012306:Risk
D003404:Creatinine