Glucose ingestion matched with total carbohydrate utilization attenuates hypoglycemia during exercise in adolescents with IDDM.
There are currently no guidelines regarding the carbohydrate (CHO) dosage required to prevent exercise-induced hypoglycemia in children with insulin-dependent diabetes mellitus (IDDM). To prevent hypoglycemia by matching glucose ingestion with total-CHO utilization, 20 adolescents with IDDM attended 2 trials: control (CT; drinking water) and glucose (GT; drinking 6-8% glucose). Participants performed 60 min of moderate-intensity cycling 100 min after insulin injection and breakfast. CT's total-CHO utilization during exercise was determined using indirect calorimetry. In GT, participants ingested glucose in the amount equal to total CHO utilization in the CT. A total of 9 participants had BG < 4.0 mmol/L in CT compared to 3 in GT (p < .05). In conclusion, glucose ingestion equal to total-CHO utilization attenuates the drop in blood glucose and reduces the likelihood of hypoglycemia during exercise in adolescents with IDDM.
Children's Exercise and Nutrition Centre, McMaster University, Hamilton, ON Canada.
M C
MC
Riddell
O
O
Bar-Or
B V
BV
Ayub
R E
RE
Calvert
G J
GJ
Heigenhauser
D000293:Adolescent; D000704:Analysis of Variance; D001786:Blood Glucose / Q000032:analysis; D002153:Calorimetry, Indirect; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism* / Q000517:prevention & control; D004040:Dietary Carbohydrates / Q000008:administration & dosage* / Q000378:metabolism; D005080:Exercise Test; D005260:Female; D005947:Glucose / Q000008:administration & dosage* / Q000378:metabolism; D006801:Humans; D007003:Hypoglycemia / Q000517:prevention & control*; D007328:Insulin / Q000627:therapeutic use; D008297:Male; D010101:Oxygen Consumption; D005082:Physical Exertion / Q000502:physiology*; D012119:Respiration
D001786:Blood Glucose; D004040:Dietary Carbohydrates; D007328:Insulin; D005947:Glucose