Chlorothalonil: lack of genotoxic potential.
Based upon analyses using a number of validated structure-activity relationship models, it is concluded that the carcinogenicity in rodents of chlorothalonil is not due to a genotoxic mechanism.
Department of Environmental and Occupational Health, University of Pittsburgh, 260 Kappa Drive-RIDC Park, Pittsburgh, PA 15238, USA. rsnkranz@vms.cis.pitt.edu
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Rosenkranz
D000818:Animals; D009152:Mutagenicity Tests; D009153:Mutagens / Q000737:chemistry / Q000633:toxicity; D009570:Nitriles / Q000737:chemistry / Q000633:toxicity; D051381:Rats; D013329:Structure-Activity Relationship
D009153:Mutagens; D009570:Nitriles; C005806:tetrachloroisophthalonitrile