Membrane receptors for soluble defense collagens.
Membrane receptors for the soluble 'defense collagens' - naturally occurring chimeric molecules that contain a recognition domain contiguous with a collagen-like triple helical domain and play a role in protecting the host from pathogens entering the blood, lung and other tissues - are being isolated. These receptors are key to understanding the mechanisms by which defense collagens influence cellular responses in order to either provide rapid 'stealth clearance' of cellular debris or to initiate the responses that lead to the destruction of harmful microbes.
Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697-3900, USA. atenner@uci.edu.
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D000818:Animals; D002352:Carrier Proteins / Q000276:immunology* / Q000378:metabolism; D015922:Complement C1q / Q000276:immunology* / Q000378:metabolism; D006023:Glycoproteins / Q000276:immunology* / Q000378:metabolism; D006801:Humans; D018960:Hyaluronan Receptors; D037241:Mannose-Binding Lectins; D008562:Membrane Glycoproteins; D008565:Membrane Proteins / Q000276:immunology / Q000378:metabolism; D024101:Mitochondrial Proteins; D011510:Proteolipids / Q000276:immunology* / Q000378:metabolism; D037663:Pulmonary Surfactant-Associated Protein D; D037661:Pulmonary Surfactant-Associated Proteins; D011663:Pulmonary Surfactants / Q000276:immunology* / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000276:immunology* / Q000378:metabolism; D011951:Receptors, Complement / Q000276:immunology / Q000378:metabolism; D011971:Receptors, Immunologic / Q000276:immunology / Q000378:metabolism; D012995:Solubility
C087299:C1QBP protein, human; D002352:Carrier Proteins; D006023:Glycoproteins; D018960:Hyaluronan Receptors; D037241:Mannose-Binding Lectins; D008562:Membrane Glycoproteins; D008565:Membrane Proteins; D024101:Mitochondrial Proteins; D011510:Proteolipids; D037663:Pulmonary Surfactant-Associated Protein D; D037661:Pulmonary Surfactant-Associated Proteins; D011663:Pulmonary Surfactants; D011956:Receptors, Cell Surface; D011951:Receptors, Complement; D011971:Receptors, Immunologic; C032402:complement 1q receptor; C116303:glycoprotein 340; C067774:surfactant protein A receptor; D015922:Complement C1q