Enteropathogenic Escherichia coli: cellular harassment.
The mechanisms by which enteropathogenic Escherichia coli (EPEC) mediates diarrhea remain a mystery. Recently a number of interesting and at times surprising results have come from studying EPEC interactions with host cells. Identification and characterization of bacterial factors, including Tir, EspA, EspB and EspD, and host responses have expanded our grasp of the diverse effects of EPEC on host cells.
DeVinney
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Biotechnology Laboratory University of British Columbia Vancouver British Columbia V6T 1Z4 Canada.
Knoechel
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D018829:Adhesins, Bacterial; D000818:Animals; D001422:Bacterial Adhesion / Q000502:physiology; D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry / Q000378:metabolism / Q000502:physiology; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism / Q000502:physiology; D002352:Carrier Proteins; D016207:Cytokines / Q000378:metabolism; D003967:Diarrhea / Q000382:microbiology; D029721:Drosophila Proteins; D004847:Epithelial Cells / Q000378:metabolism / Q000382:microbiology*; D004926:Escherichia coli / Q000378:metabolism / Q000472:pathogenicity*; D029968:Escherichia coli Proteins; D018398:Homeodomain Proteins / Q000378:metabolism / Q000502:physiology; D006801:Humans; D018832:Molecular Chaperones / Q000378:metabolism / Q000502:physiology; D011956:Receptors, Cell Surface / Q000502:physiology; D012097:Repressor Proteins / Q000502:physiology; D015398:Signal Transduction; D014157:Transcription Factors; D014774:Virulence
D018829:Adhesins, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D002352:Carrier Proteins; C112312:CesD protein, E coli; D016207:Cytokines; D029721:Drosophila Proteins; C087863:EaeB protein, E coli; D029968:Escherichia coli Proteins; C102051:EspA protein, E coli; C474481:EspD protein, E coli; D018398:Homeodomain Proteins; D018832:Molecular Chaperones; D011956:Receptors, Cell Surface; D012097:Repressor Proteins; C090049:SycH protein, Yersinia; C109287:Tir protein, E coli; D014157:Transcription Factors; C052837:eve protein, Drosophila; C073819:eaeA protein, E coli