Effect of doxycycline on the apical seal of retrograde filling materials.
In this study, we examined the effect of doxycycline hydrochloride (DH) on the apical seal. Results indicated that teeth that were retrofilled with IRM or amalgam following doxycycline irrigation had significantly less dye penetration (p < 0.05). Due to its antimicrobial activity, smear layer removal ability, and improvement of apical seal, doxycycline solution may be used as an irrigant.
Department of Restorative Dentistry, University of California, San Francisco 94143-0758, USA.
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Barkhordar
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Russel
D000704:Analysis of Variance; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004396:Coloring Agents; D003763:Dental Leakage / Q000175:diagnosis / Q000517:prevention & control*; D004318:Doxycycline / Q000494:pharmacology*; D006801:Humans; D008751:Methylene Blue; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants / Q000494:pharmacology*; D012389:Root Canal Obturation / Q000379:methods*; D016369:Smear Layer; D019227:Tooth Apex / Q000502:physiology
D000900:Anti-Bacterial Agents; D004396:Coloring Agents; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants; D004318:Doxycycline; D008751:Methylene Blue