title: Fatty acid composition of plasma and erythrocytes in term infants fed human milk and formulae with and without docosahexaenoic and arachidonic acids from egg yolk lecithin.
abstract: Human milk contains small but nutritionally significant amounts of long-chain polyunsaturated fatty acids (LCP), such as arachidonic (AA, 20:4n-6) and docosahexaenoic (DHA, 22:6n-3) acids, which are not present in most infant formulae. In the present study, the fatty acid composition of plasma and erythrocytes was determined at birth and again at 7 days, 1 and 3 months in 49 healthy full-term infants (37-42 week's gestation). One group of infants was fed exclusively with human milk (n=16) and the others were randomly assigned to a standard term formula (F) (n=15) or the same formula with egg yolk lecithin providing DHA (0.15%) and AA (0.30%) (LCP-F) (n=18). Plasma and erythrocyte LCP values of the three dietary groups did not differ at 7 days of age, but the contents of DHA and AA in plasma and erythrocytes at 1 and 3 months were significantly lower (P<0.05) in infants fed non supplemented formula than in infants fed breast milk and supplemented formula. There were no differences in plasma or erythrocyte AA or DHA concentrations between the group fed breast milk and the group fed supplemented formula during the period studied.
authors: Food Sciences and Nutrition Unit - CERTA, Faculty of Pharmacy, University of Barcelona, Spain.
authors: E
authors: E
authors: Bondía-Martínez
authors: M C
authors: MC
authors: López-Sabater
authors: A I
authors: AI
authors: Castellote-Bargalló
authors: M
authors: M
authors: Rodríguez-Palmero
authors: M J
authors: MJ
authors: González-Corbella
authors: M
authors: M
authors: Rivero-Urgell
authors: C
authors: C
authors: Campoy-Folgoso
authors: R
authors: R
authors: Bayés-García
mesh_terms: D000375:Aging; D001095:Arachidonic Acids / Q000008:administration & dosage* / Q000097:blood; D004281:Docosahexaenoic Acids / Q000008:administration & dosage* / Q000097:blood; D004530:Egg Yolk / Q000737:chemistry; D004912:Erythrocytes / Q000737:chemistry*; D005227:Fatty Acids / Q000097:blood*; D015525:Fatty Acids, Omega-3 / Q000097:blood; D006801:Humans; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D008895:Milk, Human; D010713:Phosphatidylcholines
chemical_list: D001095:Arachidonic Acids; D005227:Fatty Acids; D015525:Fatty Acids, Omega-3; D010713:Phosphatidylcholines; D004281:Docosahexaenoic Acids