title: Effects of dietary seal oil on fat metabolism.
abstract: In the 1970s, Bang and Dyerberg demonstrated that a high intake of n-3 acids in Greenland protected against ischemic heart disease. This started the interest in fish oil as a preventive component in cardiac disease. The fatty acid composition in Greenlandic diet is quite different from the one in the Danish diet, being lower in saturated fatty acids and polyunsaturated fatty acids (PUFAs) and higher in monounsatured fatty acids (MUFAs). During the last decade, evidence has suggested that the MUFA (18:1) is not a neutral dietary component but has a positive effect of its own. This paper reports on a current project undertaken to study the effect of marine MUFAs and PUFAs on atherosclerosis-related parameters and to evaluate their possible synergistic effect in the prevention of atherosclerosis. The project has recently started, so at the moment results cannot be presented. The study will be carried out as an intervention study on 50 healthy volunteers. Capsules of Greenlandic halibut oil (rich in MUFAs) and "Biomarin" (rich in n-3 PUFAs) will be tested against seal oil.
authors: Center of Arctic Environmental Medicine, University of Aarhus, Denmark.
authors: S M
authors: SM
authors: Møller
authors: J C
authors: JC
authors: Hansen
authors: E B
authors: EB
authors: Thorling
authors: G
authors: G
authors: Mulvad
authors: H S
authors: HS
authors: Pedersen
authors: P
authors: P
authors: Bjerregaard
mesh_terms: D000328:Adult; D000818:Animals; D001161:Arteriosclerosis / Q000145:classification* / Q000517:prevention & control*; D003718:Denmark; D004041:Dietary Fats / Q000378:metabolism*; D005227:Fatty Acids / Q000032:analysis*; D005395:Fish Oils / Q000008:administration & dosage*; D005504:Food Analysis; D006116:Greenland; D006801:Humans; D010865:Pilot Projects; D012016:Reference Values; D046048:Seals, Earless
chemical_list: D004041:Dietary Fats; D005227:Fatty Acids; D005395:Fish Oils