Ultrasonic thrombolysis: catheter-delivered and transcutaneous applications.
Ultrasonic thrombolysis has been proved to be an efficient and safe modality for the treatment of acute arterial occlusions in vitro and in vivo in animal studies. There have been and are ongoing parallel improvements in ultrasound technology and adjuvant pharmacological treatments for therapeutic applications. Thus therapeutic ultrasound for thrombolysis holds great promise in overcoming the limitations of current available therapies.
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Cardiac Noninvasive Laboratory, Division of Cardiology, Room #5335, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
Luo
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Nagai
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Siegel
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D000818:Animals; D001157:Arterial Occlusive Diseases / Q000628:therapy; D002404:Catheterization / Q000295:instrumentation; D017024:Chemotherapy, Adjuvant; D004195:Disease Models, Animal; D004867:Equipment Design; D006801:Humans; D009203:Myocardial Infarction / Q000628:therapy; D012449:Safety; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy / Q000628:therapy*; D014159:Transducers; D014464:Ultrasonic Therapy / Q000295:instrumentation / Q000379:methods