Personal exposure to fine particles in children correlates closely with ambient fine particles.
To investigate the validity of ambient fine-particle concentrations as a measure of exposure in epidemiological time-series studies, we established the association between personal and ambient concentrations, within subjects, over time. We conducted repeated measurements of personal and ambient fine-particle concentrations in 13 children who lived in Wageningen, The Netherlands. For each child separately, we related personal exposures to ambient concentrations in a regression analysis. The median Pearson's correlation coefficient was 0.86. Personal fine-particle concentrations were also highly correlated with ambient particulate matter (i.e., < or = 10-microm) concentrations (median Pearson's correlation coefficient = .75). Personal fine-particle concentrations were typically approximately 11 microg/m3 higher than ambient concentrations. We excluded measurements of children who were exposed to environmental tobacco smoke, and the difference was only 5 microg/m3. The findings of high correlations between personal fine-particle concentrations and both ambient fine-particle concentrations and particulate matter (i.e., < or = 10-microm) found in this group of children provide support for investigators to use ambient particulate matter concentrations to measure exposure to fine-particle concentrations in epidemiological time-series studies.
Janssen
N A
NA
Department of Environmental Sciences, Environmental and Occupational Health Unit, University of Wageningen, The Netherlands.
Hoek
G
G
Harssema
H
H
Brunekreef
B
B
D000393:Air Pollutants / Q000032:analysis*; D002648:Child; D004781:Environmental Exposure; D006801:Humans; D009426:Netherlands; D010316:Particle Size
D000393:Air Pollutants