[Endoplasmic reticulum and mitochondria as elements of mechanism of intracellular signaling in neurons].
The temporal and spatial characteristics of a transitory increase in free Ca2+ ("calcium signals") concentration were determined in various types of the mice and rat neurones. Intracellular structures: endoplasmatic reticulum and mitochondria, were shown to play a major part in formation of these signals, the structures being able to absorb the Ca2+ ions from cytosol and release them back. The contribution of these processes proves rather varying depending on internal organisation and functional assignment of a neurone.
Kostiuk
P G
PG
A. A. Bogomolets Institute of Physiology, Ukrainian Acad. Sci., Kiev.
Shmigol'
A V
AV
Voĭtenko
N V
NV
Svichar
N V
NV
Kostiuk
E P
EP
D000818:Animals; D020013:Calcium Signaling / Q000502:physiology; D004721:Endoplasmic Reticulum / Q000502:physiology*; D008564:Membrane Potentials; D051379:Mice; D008928:Mitochondria / Q000502:physiology*; D009474:Neurons / Q000502:physiology* / Q000648:ultrastructure; D051381:Rats; D015398:Signal Transduction / Q000502:physiology*