[An attempt to treat loosening of the total hip endoprosthesis in Paget disease with Aredia].
A case history of Paget's disease around the hip is presented from 1977 (intraoperative diagnosis) to 1998. Primary Weller THR as well as revision PM replacement in 1990 failed due to loosening. The use of bisodium pamidronian (Aredia, Ciba-Geigy) allowed for loosening arrest (remission of pain, preservation of extremity length, no further radiological changes) for 4 years. Aredia was well tolerated, side effects were transient and did not required therapy.
Gburek
Z
Z
Klinika Reumatologii i Rehabilitacji Narzadów Ruchu SIAM, Slaski Szpital Reumatologiczny im. gen. J. Zietka, Ustroniu.
Rybicki
A
A
D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D004164:Diphosphonates / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010001:Osteitis Deformans / Q000000981:diagnostic imaging / Q000601:surgery*; D000077268:Pamidronate; D011183:Postoperative Complications / Q000188:drug therapy*; D011475:Prosthesis Failure; D011859:Radiography
D000893:Anti-Inflammatory Agents; D004164:Diphosphonates; D000077268:Pamidronate