Allergens from mites: implications of cross-reactivity between invertebrate antigens.
Group 1 and 2 allergens are probably the most important mite allergens. Some mite allergens, such as tropomyosin, are widely cross-reactive. The prevalence of sensitization to invertebrates cannot be based solely on skin test or serologic data with the allergen extracts currently available. Purified (recombinant) allergens, selected for low cross-reactivity, are urgently needed.
Aalberse
R C
RC
Central Laboratory of the Blood Transfusion Service and Academic Medical Centre, University of Amsterdam, The Netherlands. aalberse@clb.nl
D000485:Allergens / Q000276:immunology*; D000818:Animals; D000941:Antigens / Q000276:immunology*; D003429:Cross Reactions; D006801:Humans; D007448:Invertebrates / Q000276:immunology*; D008925:Mites / Q000276:immunology*
D000485:Allergens; D000941:Antigens