Allelic drop-out in exon 2 of the hepatocyte nuclear factor-1alpha gene hinders the identification of mutations in three families with maturity-onset diabetes of the young.
Ellard
S
S
Department of Diabetes and Vascular Medicine, School of Postgraduate Medicine and Health Sciences, University of Exeter, UK. s.ellard@exeter.ac.uk
Bulman
M P
MP
Frayling
T M
TM
Allen
L I
LI
Dronsfield
M J
MJ
Tack
C J
CJ
Hattersley
A T
AT
D017668:Age of Onset; D000483:Alleles; D001483:Base Sequence / Q000235:genetics; D004268:DNA-Binding Proteins; D003920:Diabetes Mellitus / Q000453:epidemiology* / Q000235:genetics*; D005091:Exons / Q000235:genetics*; D051537:Hepatocyte Nuclear Factor 1; D051538:Hepatocyte Nuclear Factor 1-alpha; D051539:Hepatocyte Nuclear Factor 1-beta; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics*; D009687:Nuclear Proteins; D014157:Transcription Factors / Q000235:genetics*
D004268:DNA-Binding Proteins; C496487:HNF1A protein, human; C496495:HNF1B protein, human; D051538:Hepatocyte Nuclear Factor 1-alpha; D009687:Nuclear Proteins; D014157:Transcription Factors; D051537:Hepatocyte Nuclear Factor 1; D051539:Hepatocyte Nuclear Factor 1-beta