Hypertrophic and restrictive cardiomyopathies in the elderly.
Congestive heart failure (CHF) increases with age, but most CHF in the elderly is due to diastolic dysfunction with preserved systolic function. The etiology, pathophysiology, diagnosis, natural history, and treatment of hypertrophic and restrictive cardiomyopathies in the elderly are discussed as a paradigm for CHF with normal systolic function. Hypertrophic obstructive and hypertensive hypertrophic cardiomyopathies are compared and contrasted. As an example of a restrictive cardiomyopathy, the various types of amyloidosis and their clinical import in older patients are covered.
Zieman
S J
SJ
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Fortuin
N J
NJ
D000368:Aged; D002312:Cardiomyopathy, Hypertrophic / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D002313:Cardiomyopathy, Restrictive / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D006321:Heart / Q000503:physiopathology; D006801:Humans; D015995:Prevalence