Genetic susceptibility and ischaemic stroke.
In the past year the search for genetic susceptibility factors involved in ischaemic stroke has motivated a number of important studies in humans and animals. These have been focused on genetic susceptibility as a risk factor for ischaemic stroke, or as a determinant of ischaemic stroke outcome. Because there is increasing evidence that genetic factors play a role, it seems that epidemiological studies assessing both environmental and genetic risk factors may help to understand the cause of ischaemic stroke better. This may have therapeutic and preventive implications.
Elbaz
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A
INSERM unité 360, Hôpital de la Salpêtrière, Paris, France. elbaz@ccr.jussieu.fr
Amarenco
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P
D000483:Alleles; D000818:Animals; D001057:Apolipoproteins E / Q000235:genetics; D001921:Brain / Q000098:blood supply*; D002545:Brain Ischemia / Q000235:genetics*; D004195:Disease Models, Animal; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D017202:Myocardial Ischemia / Q000235:genetics*; D019001:Nitric Oxide Synthase / Q000235:genetics; D007703:Peptidyl-Dipeptidase A / Q000235:genetics; D010641:Phenotype; D011110:Polymorphism, Genetic; D014427:Twins / Q000235:genetics
D001057:Apolipoproteins E; D019001:Nitric Oxide Synthase; D007703:Peptidyl-Dipeptidase A