Adenosquamous carcinoma of the mouth: a rare variant of squamous cell carcinoma.
Adenosquamous carcinoma is a rare tumour in the oral cavity and is characterised histologically by carcinomatous change in surface epithelium, in association with adenocarcinoma affecting the ducts of minor salivary glands. Only a dozen cases have previously been reported in the oral cavity, but all have shown an aggressive course with 60% of patients dying of disease. We report three further cases and review the literature, which suggests that this lesion should be regarded as a high-grade variant of squamous cell carcinoma.
Scully
C
C
Eastman Dental Institute for Oral Health Care Sciences, University of London, UK. Cscully@eastman.ucl.ac.uk
Porter
S R
SR
Speight
P M
PM
Eveson
J W
JW
Gale
D
D
D000368:Aged; D001706:Biopsy; D018196:Carcinoma, Adenosquamous / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D009062:Mouth Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery