On the toxicity of valproic-acid.
Pancreatitis is a serious adverse effect of valproic acid (VPA). We report a case of VPA-induced pancreatitis in a dialysis patient. A brief review concerning VPA toxicity and acute pancreatitis in chronic renal patients is presented. We suggest that end-stage renal disease (ESRD) should be considered another risk factor for VPA-induced pancreatitis.
Moreiras Plaza
M
M
Department of Nephrology, Xeral-Cies Hospital, Vigo, Spain.
Rodríguez Goyanes
G
G
Cuiña
L
L
Alonso
R
R
D000208:Acute Disease; D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D004830:Epilepsy, Tonic-Clonic / Q000188:drug therapy; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D010195:Pancreatitis / Q000139:chemically induced*; D006435:Renal Dialysis; D012307:Risk Factors; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D000927:Anticonvulsants; D014635:Valproic Acid