Diffuse metastatic infiltration of a carcinoma into skeletal muscle.
Skeletal muscle is one of the most unusual sites of metastasis from any malignancy. We report a patient with rapidly progressive contractures due to metastatic infiltration of a carcinoma of unknown origin into the skeletal muscle. This 61-year-old man presented with a 1-month history of rapidly evolving, painful restriction of mobility of his right arm and his legs. Computed tomography showed diffuse metastatic nodules in all muscles, particularly in the hip abductors. Muscle biopsy revealed extensive infiltration of the muscle with carcinoma cells.
Hundt
W
W
Department of Diagnostic Radiology, Klinikum Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.
Braunschweig
R
R
Reiser
M
M
D001706:Biopsy; D018287:Carcinoma, Large Cell / Q000175:diagnosis / Q000556:secondary*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000175:diagnosis / Q000556:secondary*; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging / Q000473:pathology; D009361:Neoplasm Invasiveness; D009382:Neoplasms, Unknown Primary / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed