[Cutaneous and subcutaneous soft tissue tumors].
Superficial, especially cutaneous soft tissue tumors deserve attention because of their special biology, often with better prognosis than their deep counterparts. This fact also has been considered in the TNM Classification/UICC, as well as in the Typing of Soft Tissue Tumors/WHO.-Basically all types of soft tissue tumors can also be found in subcutaneous and cutaneous localisation. Dermatofibrosarcoma protuberans, however, is a typical superficial tumor involving cutis and frequently the superficial subcutis. Superficial leiomyosarcoma and atypical fibroxanthoma are examples of sarcomas, which in spite of histological criteria, which generally are associated with high grade malignancy, behave as low grade malignant tumors, i.e. chiefly with risk of recurrency albeit negligible risk of metastases. Angiosarcoma and epitheloid sarcoma, on the other hand, may also metastasize, even if restricted to the cutis. Here histological criteria as numerous mitoses, cellular atypia and tumor necrosis, may additionally influence the prognosis. In conclusion it is evident that exact tumor classification is the basic requirement for an optimal, prognosis-adapted therapy. Prerequisite, however, is a precise clinico-pathological correlation to understand the biology of the different tumor entities.
Meister
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D006394:Hemangiosarcoma / Q000145:classification / Q000473:pathology; D006801:Humans; D012509:Sarcoma / Q000145:classification / Q000473:pathology; D012878:Skin Neoplasms / Q000145:classification* / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000145:classification* / Q000473:pathology*