title: Dynamic modeling of meta- and para-nitrobenzoate metabolism by a mixed co-immobilized culture of comamonas spp. JS46 and JS47
abstract: A model describing the transient activity of a mixed immobilized culture of Comamonas spp. JS46 and JS47 growing on mixed substrates is presented. The transient periods considered are those following changes in the feed carbon source, which alternated between meta- and para-nitrobenzoate. The feed profile alternately starved one of the species in the mixed culture. The response of the system, as quantified by the reactor effluent substrate concentrations, is dictated by the activity of the biomass and the appropriate biochemical pathway. As detailed mechanistic pathway information is not available, respirometry has been used to characterize both facets of activity. Two parameters were introduced: Psi representing pathway activity and Gamma representing biomass activity; a detailed description of the analysis is included. The model is compared to experimental investigation of the system and describes the reactor response well. The agreement between model and experiment suggests the usefulness of oxygen kinetics as global measurements to describe complex systems when mechanistic detail is not available. Copyright 1998 John Wiley & Sons, Inc.
authors: Department of Chemical Engineering, North Carolina State University, Box 7905, Raleigh, North Carolina 27695-7905, USA.
authors: JL
authors: Goodall
authors: SW
authors: Peretti