title: Colworth Medal lecture. Detection, repair and signalling of DNA double-strand breaks.
authors: Wellcome/CRC Institute, Cambridge, U.K.
authors: S P
authors: SP
authors: Jackson
mesh_terms: D000818:Animals; D034961:Antigens, Nuclear; D001363:Awards and Prizes; D003001:Cloning, Molecular; D004249:DNA Damage; D004265:DNA Helicases; D000072481:DNA Ligase ATP; D011088:DNA Ligases / Q000378:metabolism; D004260:DNA Repair; D018076:DNA, Complementary / Q000235:genetics; D051747:DNA-Activated Protein Kinase; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D049673:History, 20th Century; D006801:Humans; D000072200:Ku Autoantigen; D051379:Mice; D016513:Mice, SCID; D008954:Models, Biological; D009154:Mutation; D009687:Nuclear Proteins / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism; D012318:RNA Polymerase I / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins
chemical_list: D034961:Antigens, Nuclear; D018076:DNA, Complementary; D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; D029701:Saccharomyces cerevisiae Proteins; C101467:XRCC4 protein, human; C081647:high affinity DNA-binding factor, S cerevisiae; D051747:DNA-Activated Protein Kinase; C497263:PRKDC protein, human; D017346:Protein Serine-Threonine Kinases; D012318:RNA Polymerase I; D004265:DNA Helicases; C106893:XRCC5 protein, human; C000606509:Xrcc6 protein, human; C000606510:Xrcc6 protein, mouse; D000072200:Ku Autoantigen; D011088:DNA Ligases; D000072481:DNA Ligase ATP