Transcutaneous nitroglycerine in the treatment of erectile dysfunction: a placebo controlled clinical trial.
Transcutaneous nitroglycerine has previously been reported to be effective in the treatment of erectile dysfunction. We present our results with the drug in a randomised, placebo controlled, double-blind crossover study. The effect of the drug has been evaluated both under laboratory conditions and in a home study. Eighteen men were included in the study. No effect of nitroglycerine could be demonstrated under laboratory conditions by application of the Rigiscan Monitor. In the home study there was no statistical significant effect of transcutaneous nitroglycerine compared to placebo (P= 0.2813).
Gramkow
J
J
Department of Surgery, Hilleroed Hospital, Denmark. gramkow@dadlnet.dk
Lendorf
A
A
Zhu
J
J
Meyhoff
H H
HH
D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D018592:Cross-Over Studies; D004311:Double-Blind Method; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D010410:Penile Erection / Q000187:drug effects; D010413:Penis / Q000187:drug effects*; D010919:Placebos; D014665:Vasodilator Agents / Q000008:administration & dosage* / Q000627:therapeutic use
D010919:Placebos; D014665:Vasodilator Agents; D005996:Nitroglycerin