Modified PNAs: a simple method for the synthesis of monomeric building blocks.
The synthesis of PNA-monomers with variations in the substitution pattern using the Ugi-Reaction is described. The one-pot procedure leads to new totally protected PNA-monomers which can be selectively cleaved to N-protected monomeric building blocks for PNA synthesis.
Maison
W
W
Fachbereich Chemie, Universität Oldenburg, Germany.
Schlemminger
I
I
Westerhoff
O
O
Martens
J
J
D009690:Nucleic Acid Conformation; D020135:Peptide Nucleic Acids / Q000138:chemical synthesis* / Q000737:chemistry
D020135:Peptide Nucleic Acids