Antimicrobial resistance patterns of Bacteroides fragilis group organisms in Korea.
Antimicrobial resistance patterns of 913 clinical isolates of Bacteroides fragilis group organisms were monitored during an 8-year period in Korea. In general the resistance rates of the non-fragilis B. fragilis group species were higher than those of B. fragilis for all the drugs tested. The rate of resistance to clindamycin remarkably increased and those to some beta-lactam drugs such as piperacillin and cefotaxime also increased. No isolates were found to be resistant to imipenem, metronidazole, or chloramphenicol. beta-lactam and beta-lactamase inhibitor combinations and cefoxitin were more active than the other beta-lactams. Therefore, these agents may be considered when empirical selection of antimicrobial agents is required to treat severe anaerobic infections.
Lee
K
K
Department of Clinical Pathology, Yonsei University College of Medicine, Seoul, Korea. leekcp@yumc.yonsei.ac.kr
Shin
H B
HB
Chong
Y
Y
D001441:Bacteroides fragilis / Q000502:physiology*; D004352:Drug Resistance, Microbial / Q000502:physiology*; D006801:Humans; D007723:Korea; D008826:Microbial Sensitivity Tests