Psychoneuroendocrine aspects of temporolimbic epilepsy. Part III: Case reports.
Many reproductive steroids have neuroactive effects that can modulate neuronal excitability and influence emotions. Emotional disorders may result when 1) abnormal endocrine states interact with normal brain, 2) normal endocrine states interact with abnormal brain, and 3) abnormal endocrine states interact with abnormal brain. An understanding of these pathogenetic relationships and the potential therapeutic role of reproductive hormones should lead to a more effective and comprehensive management of women and men with anxiety and mood disorders.
Herzog
A G
AG
Harvard Neuroendocrine Unit, Beth Israel Deaconess Medical Center, Department of Neurology, Harvard Medical School, USA.
D000328:Adult; D001008:Anxiety Disorders / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology; D004700:Endocrine System Diseases / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology; D004827:Epilepsy / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D019964:Mood Disorders / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology