[The structural and functional organization of the promoter region of the human CD4-receptor gene].
Receptor CD4, expressed on the surface of immunocompetent cells, plays the key role in the pathogenesis of HIV infection, facilitating the penetration of the virus into the susceptible tissues of the host body. In this work the nucleotide sequence of the site on the gene of receptor CD4, responsible for the regulation of its transcription, has been determined.
Zverev
V V
VV
Research Institute of Viral Preparations, Moscow, Russia.
Sidorov
A V
AV
Borzykh
O A
OA
Blinov
V M
VM
D001483:Base Sequence; D015704:CD4 Antigens / Q000235:genetics*; D015658:HIV Infections / Q000209:etiology / Q000235:genetics; D015497:HIV-1; D006801:Humans; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics; D014158:Transcription, Genetic / Q000235:genetics
D015704:CD4 Antigens; D014157:Transcription Factors