ROUGH SHEATH2: a Myb protein that represses knox homeobox genes in maize lateral organ primordia.
The regulation of members of the knotted1-like homeobox (knox) gene family is required for the normal initiation and development of lateral organs. The maize rough sheath2 (rs2) gene, which encodes a Myb-domain protein, is expressed in lateral organ primordia and their initials. Mutations in the rs2 gene permit ectopic expression of knox genes in leaf and floral primordia, causing a variety of developmental defects. Ectopic KNOX protein accumulation in rs2 mutants occurs in a subset of the normal rs2-expressing cells. This variegated accumulation of KNOX proteins in rs2 mutants suggests that rs2 represses knox expression through epigenetic means.
Timmermans
M C
MC
Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA.
Hudson
A
A
Becraft
P W
PW
Nelson
T
T
D000595:Amino Acid Sequence; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D015536:Down-Regulation; D018506:Gene Expression Regulation, Plant; D005801:Genes, Homeobox; D017343:Genes, Plant; D018398:Homeodomain Proteins / Q000235:genetics* / Q000378:metabolism; D018519:Meristem / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D008969:Molecular Sequence Data; D009154:Mutation; D018515:Plant Leaves / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D020598:Proto-Oncogene Proteins c-myb; D012097:Repressor Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D016415:Sequence Alignment; D003313:Zea mays / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism
D004268:DNA-Binding Proteins; D018398:Homeodomain Proteins; C095848:Kn1 protein, plant; D010940:Plant Proteins; D020598:Proto-Oncogene Proteins c-myb; D012097:Repressor Proteins; C118404:rough sheath2 protein, Zea mays