title: Maximisation of the erectile response in the investigation of impotence.
abstract: The aim of this study was to assess whether redosing with a combination of intracavernosal (IC) vasoactive agents could produce a complete erectile response, thereby providing a reliable and reproducible method of dynamic investigation of erectile dysfunction. Forty-one impotent men were redosed with a combination intracavernosal agents until a constant penile rigidity was achieved. They were then shown audiovisual sexual stimulation (VES) by means of a videotape. The erectile responses were monitored continuously by RigiScan (Dacomed).
  
  
  RESULTS
  Despite a constant rigidity with intracavernous injection (ICI), 16 men (39%) still had an improved response with VES that was clinically detectable.
  
  
  CONCLUSIONS
  Dynamic investigation of erectile dysfunction with a combination and redosing of IC agents may still lead to an incomplete erectile response. This may potentially lead to patients being incorrectly labelled and confirms the limitations of follow-up studies using dynamic tests of erectile function.
authors: The Norfolk and Norwich Hospital, UK.
authors: R D
authors: RD
authors: Mills
authors: K K
authors: KK
authors: Sethia
mesh_terms: D000368:Aged; D000527:Alprostadil / Q000008:administration & dosage; D001296:Audiovisual Aids; D007172:Erectile Dysfunction / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000008:administration & dosage; D010410:Penile Erection; D010413:Penis / Q000187:drug effects; D010646:Phentolamine / Q000008:administration & dosage; D014665:Vasodilator Agents / Q000008:administration & dosage*
chemical_list: D014665:Vasodilator Agents; D010208:Papaverine; D000527:Alprostadil; D010646:Phentolamine