Protein kinase C delta.
The protein kinase C (PKC) family consists of 11 isoenzymes that, due to structural and enzymatic differences, can be subdivided into three groups: The Ca(2+)-dependent, diacylglycerol (DAG)-activated cPKCs (conventional PKCs: alpha, beta 1, beta 2, gamma); the Ca(2+)-independent, DAG-activated nPKCs (novel PKCs: delta, epsilon, eta, theta, mu), and the Ca(2+)-dependent, DAG non-responsive aPKCs (atypical PKCs: zeta, lambda/iota). PKC mu is a novel PKC, but with some special structural and enzymatic properties.
Gschwendt
M
M
German Cancer Research Center, Heidelberg, Germany. m.gschwendt@dkfz-heidelberg.de
D000818:Animals; D001665:Binding Sites; D004789:Enzyme Activation; D007527:Isoenzymes / Q000737:chemistry*; D010766:Phosphorylation; D011493:Protein Kinase C / Q000737:chemistry*; D051745:Protein Kinase C-delta; D013379:Substrate Specificity
D007527:Isoenzymes; D011493:Protein Kinase C; D051745:Protein Kinase C-delta