title: Effect of caudal block on the plasma adrenaline and noradrenaline concentrations in paediatric patients undergoing ilioinguinal herniorrhaphy.
abstract: This study compared the effect of two anaesthetic techniques on the catecholamine levels in children undergoing ilioinguinal herniorrhaphy. Forty male paediatric patients ASA class I were allocated randomly to one of two groups: the control group (n = 20) received general anaesthesia including intravenous fentanyl; and the caudal group (n = 20) received caudal anaesthesia with bupivacaine 0.25% 1 mL kg-1 combined with general anaesthesia but without opioids. Plasma adrenaline and noradrenaline concentrations were measured at induction, at the end of surgery and in the post-anaesthesia care unit (PACU). In the caudal group, there were significant decreases in the adrenaline and noradrenaline concentrations at the end of surgery and in the PACU compared with baseline concentrations. In the control group, there was a significant increase in PACU concentrations of adrenaline and noradrenaline compared with baseline concentrations. These findings suggest that the addition of a caudal block to general anaesthesia in children undergoing ilioinguinal herniorrhaphy decreases significantly the neurohormonal responses to surgery.
authors: Department of Anaesthesia, Bnai-Zion Medical Centre, Haifa, Israel.
authors: L A
authors: LA
authors: Gaitini
authors: M
authors: M
authors: Somri
authors: S J
authors: SJ
authors: Vaida
authors: M
authors: M
authors: Fradis
authors: E
authors: E
authors: Sabo
authors: J
authors: J
authors: Mogilner
authors: N
authors: N
authors: Levy
authors: A
authors: A
authors: Greenberg
authors: S
authors: S
authors: Lischinsky
authors: O
authors: O
authors: Zinder
mesh_terms: D000763:Anesthesia, Caudal; D000768:Anesthesia, General; D018686:Anesthetics, Intravenous; D000779:Anesthetics, Local; D002045:Bupivacaine; D002648:Child; D002675:Child, Preschool; D004837:Epinephrine / Q000097:blood*; D005283:Fentanyl; D006552:Hernia, Inguinal / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D009638:Norepinephrine / Q000097:blood*; D013312:Stress, Physiological / Q000097:blood / Q000209:etiology
chemical_list: D018686:Anesthetics, Intravenous; D000779:Anesthetics, Local; D005283:Fentanyl; D009638:Norepinephrine; D002045:Bupivacaine; D004837:Epinephrine