Outer hair cells isolated from the organ of corti exposed to increased hydrostatic pressure.
A model using outer hair cells isolated from the guinea pig organ of Corti was used to study the effects of changes in hydrostatic pressure. Outer hair cells were placed in a closed chamber and the pressure was raised to levels corresponding to pressures measured inside the cochlea or higher. No changes in cell shape could be detected using either videomicroscopy or confocal microscopy. No clear changes were observed using a potentiometric vital dye.
Conradi
P
P
ENT Research Laboratory, King Gustaf V Research Institute, Karolinska Hospital, Stockholm, Sweden.
Ulfendahl
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M
D000818:Animals; D006168:Guinea Pigs; D018072:Hair Cells, Auditory, Outer / Q000502:physiology* / Q000648:ultrastructure; D006874:Hydrostatic Pressure; D007091:Image Processing, Computer-Assisted; D018613:Microscopy, Confocal; D018715:Microscopy, Video