title: Leukoencephalopathy complicating an Ommaya reservoir and chemotherapy.
abstract: We describe the imaging findings in an unusual case of biopsy-proven, methotrexate-induced leukoencephalopathy complicating a malfunctioning Ommaya reservoir in a patient with lymphoma.
authors: Department of Radiology, University of North Carolina-Chapel Hill, 27599-7510, USA. jeff_stone@med.unc.edu
authors: J A
authors: JA
authors: Stone
authors: M
authors: M
authors: Castillo
authors: S K
authors: SK
authors: Mukherji
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects*; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000209:etiology; D002408:Catheters, Indwelling / Q000009:adverse effects*; D002552:Cerebral Ventricles; D004868:Equipment Failure; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000150:complications; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged
chemical_list: D000964:Antimetabolites, Antineoplastic; D008727:Methotrexate