title: Macro-orchidism in juvenile hypothyroidism.
abstract: A boy, aged 16 years, with absence of development of the secondary sex characteristics, inappropriately large testes for his stage of puberty, and short stature is described. The symptoms were secondary to long-standing prepubertal hypothyroidism. Following therapy with thyroxine, there was a rapid advancement in growth velocity, full development of the secondary sex characteristics, and reduction in the size of the testes.
authors: Third Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Greece.
authors: D K
authors: DK
authors: Panidis
authors: D H
authors: DH
authors: Rousso
mesh_terms: D000293:Adolescent; D006801:Humans; D007037:Hypothyroidism / Q000503:physiopathology*; D008297:Male; D013737:Testis / Q000002:abnormalities*