[The effect of new H1-receptor antagonists on cardiovascular system].
The authors present effects of new H1-receptor antagonists--terfenadine and astemizol on cardiovascular system in humans. The role of interactions between terfenadine and astemizol and other drugs is underlined. Effects of hepatic and heart diseases as well as astemizol and terfenadine overdose on their pharmacokinetics are also showed.
Pietrzkowicz
M
M
Kliniki Pneumonologii i Alergologii Akademi Medycznej w Lodzi.
Grzelewska-Rzymowska
I
I
D016589:Astemizole / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects*; D006634:Histamine H1 Antagonists / Q000494:pharmacology*; D006801:Humans; D016593:Terfenadine / Q000494:pharmacology*
D006634:Histamine H1 Antagonists; D016593:Terfenadine; D016589:Astemizole