Is sunlight an aetiological agent in the genesis of retinoblastoma?
The incidence of unilateral, but not bilateral, retinoblastoma in human populations at different geographical locations increases significantly with ambient erythemal dose of ultraviolet B radiation from sunlight. This supports the hypothesis that sunlight plays a role in retinoblastoma formation.
Hooper
M L
ML
Department of Pathology, Molecular Medicine Centre, University of Edinburgh, Western General Hospital, UK.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D014943:Global Health; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019572:Retinal Neoplasms / Q000453:epidemiology / Q000209:etiology*; D012175:Retinoblastoma / Q000453:epidemiology / Q000209:etiology*; D013472:Sunlight / Q000009:adverse effects*; D019371:Topography, Medical