[Dependence of the elastic characteristics and contractile activity of the rat tail artery on the transmural difference of potentials].
Change in the diffuse portion of the double electric layer at the blood-vascular wall border under the effect of thorium nitric oxide and heparin affects the tone and contractile ability of the rat tail artery: thorium diminishes the vessel rigidity and the amplitude of its contractile response, whereas heparin augments the rigidity as well as the amplitude of the response. Thorium nitric oxide also diminishes rigidity of the vessel connective tissue skeleton. The difference of potentials between the vessel lumen and its wall seems to be capable of affecting the contractile apparatus of the smooth muscle cells by means of activation of potential-sensitive ionic channels.
Nozdrachev
A D
AD
Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg, Russia.
Didenko
A V
AV
D000818:Animals; D001158:Arteries / Q000502:physiology*; D004548:Elasticity; D004558:Electric Stimulation; D004594:Electrophysiology; D006493:Heparin / Q000494:pharmacology; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D013623:Tail / Q000098:blood supply; D017970:Thorium Compounds / Q000494:pharmacology
D017970:Thorium Compounds; D006493:Heparin; C036680:thorium nitrate