[Hormonal regulation of the Ca+ transport in blood and vascular cells].
The main pathways of regulation of cytoplasm Ca2+ level with hormones and growth factors, as well as mechanisms of regulation of G-proteins, phospholipase C, Ca-channels, adenylate cyclase, guanylate cyclase, and protein kinase C, are discussed. Regulation of cytoplasm Ca2+ in vascular and blood cells with inositol phosphates, cAMP and cGMP, is stressed. The review summarises data on membrane receptors, G-proteins, protein kinases and their targets involved in regulation of Ca2+ turnover in platelets, endothelial and smooth muscle cells.
Tkachuk
V A
VA
School of Medicine, Moscow State University, Vorobyevy Gory, Russia.
D000818:Animals; D001692:Biological Transport / Q000502:physiology; D001773:Blood Cells / Q000378:metabolism*; D001808:Blood Vessels / Q000166:cytology / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism*; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism; D006728:Hormones / Q000502:physiology*; D006801:Humans; D009131:Muscle, Smooth, Vascular / Q000166:cytology / Q000378:metabolism
D006728:Hormones; D002118:Calcium