title: Mycobacterium kansasii infection in a Paris suburb: comparison of disease presentation and outcome according to human immunodeficiency virus status. Groupe dEtude Des Mycobactéries de la Seine-Saint-Denis.
abstract: METHODS
  Department of Seine-Saint-Denis, France.
  
  
  OBJECTIVE
  To compare the presentation and outcome of Mycobacterium kansasii infections according to human immunodeficiency virus (HIV) status.
  
  
  METHODS
  Retrospective analysis of all the medical charts of adults meeting the diagnostic criteria of the American Thoracic Society for M. kansasii infection between 1991 and 1995.
  
  
  RESULTS
  Between 1991 and 1995, 35 cases (23 HIV-[6%] and 12 HIV+ [34%]) were found, giving an annual incidence of 0.5/100000. The following particularities were common to both groups: 1) frequency and prominence of respiratory and general symptoms, 2) rarity of clinically apparent extra-thoracic involvement, 3) bacteriological confirmation mostly obtained with respiratory tract specimens, 4) favourable bacteriological outcome, and 5) low mortality attributable to the mycobacterial infection. The most striking differences concerned chest radiography: HIV- patients had apical cavitated and nodular lesions, while HIV+ patients exhibited a variety of other patterns, including alveolar infiltrates, miliary lesions and/or thoracic lymphadenopathy.
  
  
  CONCLUSIONS
  Apart from pulmonary radiographic differences, presentation and short-term outcome of M. kansasii infections were similar in HIV+ and HIV-patients.
authors: Service de Médecine Interne et Centre de Recherche en Pathologie Infectieuse et Tropicale, Bobigny, France.
authors: O
authors: O
authors: Lortholary
authors: F
authors: F
authors: Deniel
authors: P
authors: P
authors: Boudon
authors: M P
authors: MP
authors: Le Pennec
authors: M
authors: M
authors: Mathieu
authors: M
authors: M
authors: Soilleux
authors: C
authors: C
authors: Le Pendeven
authors: P
authors: P
authors: Loiseau
authors: V
authors: V
authors: Vincent
authors: D
authors: D
authors: Valeyre
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005602:France; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications* / Q000175:diagnosis* / Q000000981:diagnostic imaging; D019909:Mycobacterium kansasii; D011859:Radiography; D012189:Retrospective Studies