Effect of nitric oxide releasers on some metabolic processes of rabbit spermatozoa.
The authors investigated the possible effect of nitric oxide (NO) releasers (the free radical form of nitrogen monoxide, which control some functions of many cells) on rabbit spermatozoa. A significant (P < .01) increment was found in the percentage of the acrosome reaction in rabbit spermatozoa incubated for 30-60 min in presence of the NO releasers sodium nitroprusside (SNP) and N-acetyl-S-nitroso cysteine (NACysSNO), but not with S-nitroso cysteine (CysSNO). This effect was reverted or lowered when the NO scavenger HbO2 was included in the medium. The effects of SNP and NACysSNO on acrosome reaction do not appear to be related to glucose utilization, viability, or lipid peroxidation.
Guzmán-Grenfell
A M
AM
Unidad de Investigación Médica en Bioquimica, Coordinación de Investigación Médica, Centro Médico Nacional Siglo XXI, Instituto Mesicano del Seguro Social, Mexico City, Mexico.
Hernández
S R
SR
González-Martínez
M T
MT
Hicks
J J
JJ
D000818:Animals; D008297:Male; D009569:Nitric Oxide / Q000378:metabolism*; D011817:Rabbits; D013094:Spermatozoa / Q000378:metabolism*
D009569:Nitric Oxide