title: Helicobacter pylori in a Chukotka Native male population.
abstract: Helicobacter pylori (HP) is a widespread human pathogen closely associated with gastroduodenal diseases. Thirty-four males from one of the settlements of coastal Chukotka (72% of total adult male population, mean age 31.6 years) underwent upper endoscopy, and HP was examined histologically in antral biopsies (Giemsa stain). Histology revealed normal mucosa in 16%, antral superficial gastritis in 29%, and atrophic gastritis in 55%. HP was found in 40% of histological specimens of normal mucosa, in 100% of superficial gastritis, and in 77% of atrophic gastritis. Correlation was found between the degree of bacterial contamination and both the activity of gastritis and grade of mononuclear infiltration. Data indicate a high prevalence of HP among Chukotka Natives (77%) which may partly explain the significant frequency of antral gastritis in this population.
authors: Institute of Internal Medicine, Novosibirsk, Russia.
authors: O V
authors: OV
authors: Reshetnikov
authors: Y P
authors: YP
authors: Nikitin
authors: M V
authors: MV
authors: Kholmogortsev
authors: S A
authors: SA
authors: Kurilovich
authors: O A
authors: OA
authors: Pycllik
mesh_terms: D000328:Adult; D003625:Data Collection; D005753:Gastric Mucosa / Q000382:microbiology; D005756:Gastritis / Q000175:diagnosis / Q000453:epidemiology / Q000208:ethnology*; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000453:epidemiology / Q000208:ethnology* / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D004930:Inuit / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012424:Rural Population; D012426:Russia / Q000453:epidemiology