title: Pregnancy in patients with systemic lupus erythematosus.
abstract: We reviewed the obstetrical performance and outcome of 15 pregnancies in patients with systemic lupus erythematosus (SLE) (study group) and compared them with 45 age and parity-matched normal pregnancies (control group). Eleven women (73.8%) were in remission phase and 4 (26.7%) had active disease at the time of conception. The time interval between disease diagnosis and the index pregnancy was 4.2 +/- 2.5 years. Two patients with renal involvement had lupus flare-up during the antenatal period. There was no case of lupus flare-up in the postpartum period. Gestational age at delivery was significantly lower in SLE patients (35.9 +/- 2.5 weeks) compared to the control group (37.4 +/- 2.2 weeks). The incidence of intrauterine growth retardation was significantly higher in the SLE patients (40%). There was no case of neonatal lupus or congenital heart block.
authors: Department of Obstetrics and Gynaecology, Nehru Hospital, Chandigarh, India.
authors: N
authors: N
authors: Aggarwal
authors: H
authors: H
authors: Sawhney
authors: K
authors: K
authors: Vasishta
authors: S
authors: S
authors: Chopra
authors: P
authors: P
authors: Bambery
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D036861:Delivery, Obstetric / Q000379:methods; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D006801:Humans; D015994:Incidence; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D011256:Pregnancy Outcome; D012008:Recurrence; D013256:Steroids
chemical_list: D000893:Anti-Inflammatory Agents; D013256:Steroids