title: [Intra-oral therapy of borderline sleep-related respiratory disorders with a modified protrusion-fixation of the mandible].
abstract: BACKGROUND
  Aim of this study was the investigation of the efficacy and acceptance by mechanic-prosthetic mandibular protrusion for patients with mild to moderate OSAS.
  
  
  METHODS
  During interdisciplinary teamwork between pneumology (sleep medicine) and dentistry we studied the change in the apnoea-index (AI) of 21 unselected patients treated with a modified oral appliance according to Lyon using less protrusion of the mandible and individual occlusion of the jaws. All patients were asked to rate their complaint-score using the oral appliance.
  
  
  RESULTS
  21 patients--aged 55.03 +/- 9.71 years; body mass index (BMI) 28.6 +/- 2.4 kg/m2 (mean value +/- SD)--had an improvement of apnoea-index (1/h) high significant (p < 0.0005). (Al before therapy 15.25 +/- 6.6; Al with therapy 6.07 +/- 3.7). Using a validated ambulatory respiratory evaluation device we saw an improvement in the Al of 57% +/- 19% during the estimated sleeptime of 6 h 12 min +/- 30 min. After a wearing-time of about 6 months the low complaint-score of the patients verified the high acceptance and efficacy of the modified oral appliance.
  
  
  CONCLUSIONS
  The modified oral appliance of Lyon can improve disease severity, life- and sleep-quality of patients with mild to moderate OSAS. Engaged teamwork of sleep medicine and dentistry is necessary to take care of a very individual and carefully fixation and occlusion of the mandible, resulting a continuing compliance and efficacy for the patients.
authors: Zahnärztliche Gemeinschaftspraxis Stuttgart.
authors: B
authors: B
authors: Athen
authors: B
authors: B
authors: Athen
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D009064:Mouth Protectors; D009968:Orthodontic Appliances, Removable; D010342:Patient Acceptance of Health Care; D017286:Polysomnography; D012891:Sleep Apnea Syndromes / Q000209:etiology / Q000534:rehabilitation*; D016896:Treatment Outcome