Osteonecrosis of the hip in sickle-cell disease associated with tuberculous arthritis. A review of 15 cases.
We report a study of 15 cases of tuberculous hips with sickle-cell disease who presented during 1991-1993. Although the osteonecrosis was long-standing, biopsy was nearly always required to reveal the more recent tuberculous infection. Management consisted of 6 months of anti-tuberculous chemotherapy with appropriate palliative surgery 5-8 weeks after the start of drug treatment. The operative techniques which we used are described. The results were good both post-operatively, and in 12 patients followed-up at an average of 3 years. We recommend this combined management for the treatment of secondary tuberculous infections of hips previously damaged by sickle-cell disease.
Varango
G
G
Service de Traumatologie-Orthopédie, CHU de Yopougon, Abidjan, Ivory Coast.
Bamba
I
I
Kodo
M
M
Dao
A
A
Lambin
Y
Y
D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001170:Arthritis, Infectious / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D017024:Chemotherapy, Adjuvant; D005260:Female; D005500:Follow-Up Studies; D006621:Hip Joint; D006801:Humans; D008297:Male; D008875:Middle Aged; D010020:Osteonecrosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery*; D011859:Radiography; D016059:Range of Motion, Articular; D016896:Treatment Outcome; D014394:Tuberculosis, Osteoarticular / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy*; D016138:Walking
D000995:Antitubercular Agents