Biotransformation of the fungistatic sesquiterpenoid patchoulol by botrytis cinerea
Biotransformation of the fungistatic sesquiterpenoid patchoulol (1) by the fungus Botrytis cinerea affords the 5-, 7- and (8R)-hydroxy (2, 3, and 5) derivatives as the major metabolites, together with a number of minor metabolites (4, 6-9) arising from hydroxylation at C-2, C-3, C-5, C-9, C-13, and C-14.
Aleu
J
Departamento de Quimica Organica, Facultad de Ciencias, Universidad de Cadiz, Apdo. 40, 11510 Puerto Real, Cadiz, Spain, and The School of Chemistry, Physics and Enviromental Science, University of Sussex, Brighton, Sussex BN1 9QJ.
Hanson
JR
Galan
RH
Collado
IG