title: Down-weighting of multiple affected sib pairs leads to biased likelihood-ratio tests, under the assumption of no linkage.
authors: C M
authors: CM
authors: Greenwood
authors: S B
authors: SB
authors: Bull
mesh_terms: D015982:Bias; D002874:Chromosome Mapping / Q000379:methods / Q000706:statistics & numerical data*; D005787:Gene Frequency / Q000235:genetics; D008040:Genetic Linkage / Q000235:genetics*; D006801:Humans; D016013:Likelihood Functions; D016555:Matched-Pair Analysis; D008957:Models, Genetic; D009679:Nuclear Family; D016008:Statistical Distributions