Novel cytokine release inhibitors. Part IV: analogs of podocarpic acid.
Podocarpic acid derivatives as cytokine (IL-1beta) release inhibitors are discussed.
He
W
W
Department of Medicinal Chemistry, Rhône-Poulenc Rorer Central Research, Collegeville, PA 19426, USA.
Gavai
A
A
Huang
F C
FC
Regan
J
J
Hanney
B
B
Poli
G
G
Bruno
J
J
Chan
W K
WK
Djuric
S W
SW
Yu
K T
KT
Zilberstein
A
A
D045784:Abietanes; D007375:Interleukin-1 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010616:Phenanthrenes / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
D045784:Abietanes; D007375:Interleukin-1; D010616:Phenanthrenes; C002470:podocarpic acid