Epidemiology and prophylaxis of endemic goitre in the Bwa village of Sirao (Mali).
A study was conducted in Mali, in some villages exposed to iodine deficiency disorders (IDD). To treat and, above all, prevent endemic goitre, Lipiodol UF was dispensed in two ways: by intra-muscular injection (475 mg I) or by oral administration (48 mg I to 240 mg I). In two cases, hormone levels regained normal values and thyroid hypertrophies regressed significantly. Nevertheless, the impact of the treatment on the size of the goitres seems to be in favour of injections; which is probably due to the fact that in the village which received Lipiodol UF per os, many goitres were nodular.
Roux
F
F
Laboratory of Radio-Analyses, Hospital for Conception, Marseille, France.
Bellis
G
G
Rhaly
A A
AA
Monier
C
C
Bisset
J P
JP
Aquaron
R
R
Chaventré
A
A
D000284:Administration, Oral; D005260:Female; D006043:Goiter, Endemic / Q000453:epidemiology* / Q000517:prevention & control*; D006801:Humans; D007273:Injections, Intramuscular; D007459:Iodized Oil / Q000008:administration & dosage; D008297:Male; D008302:Mali / Q000453:epidemiology
D007459:Iodized Oil