title: Morbidity from asthma in relation to regular treatment: a community based study.
abstract: BACKGROUND
  The extent to which asthma morbidity in the community occurs in patients who are having relatively little treatment or in those on step 3 or above of the British asthma management guidelines is uncertain. We have looked at this in a community population in southern Nottinghamshire.
  
  
  METHODS
  A cross sectional review of treatment in all patients over the age of four with diagnosed asthma was carried out in five large general practices (population 38 865) in 1995/6 using computerised general practice records. The patients' usual treatment was obtained from prescription data and categorised by the appropriate step on the British guidelines on asthma management. Two measures of morbidity, the request for 10 or more short acting beta agonist inhalers a year or the need for a course of oral corticosteroids in the last year, were related to the regular treatment of the patients.
  
  
  RESULTS
  Of the 3373 patients (8. 7%) given a diagnosis of asthma, the percentage on steps 1, 2, 3, 4, and 5 of treatment were 54%, 22%, 11%, 3.6%, and 1%, respectively, with a further 8% having had no treatment. During the past year 13. 6% had been prescribed 10 or more beta agonist inhalers and 12.5% had received at least one course of oral corticosteroids. Both measures occurred more frequently in patients taking more prophylactic treatment (step 3 or above). Nevertheless, because most patients were on steps 1 and 2 of the treatment guidelines, more than half the patients requiring high doses of inhaled beta agonists or a course of oral prednisolone came from those taking low dose or no regular inhaled corticosteroid.
  
  
  CONCLUSIONS
  Evidence of morbidity from asthma was found in many patients taking little or no prophylactic medication and this should be amenable to improved education. A different approach may be needed for patients with continuing morbidity who are already taking higher doses of prophylactic medication.
authors: Division of Respiratory Medicine, City Hospital, Hucknall Road, Nottingham NG5 1PB, UK.
authors: L J
authors: LJ
authors: Walsh
authors: C A
authors: CA
authors: Wong
authors: S
authors: S
authors: Cooper
authors: A R
authors: AR
authors: Guhan
authors: M
authors: M
authors: Pringle
authors: A E
authors: AE
authors: Tattersfield
mesh_terms: D000293:Adolescent; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004334:Drug Administration Schedule; D005194:Family Practice; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D010349:Patient Compliance; D017410:Practice Guidelines as Topic; D015995:Prevalence
chemical_list: D000318:Adrenergic beta-Agonists; D005938:Glucocorticoids