Detection of chromatin-associated hydroxyl radicals generated by DNA-bound metal compounds and antitumor antibiotics.
Makrigiorgos
G M
GM
Joint Center for Radiation Therapy, Harvard Medical School, Boston, MA 02215, USA,
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000378:metabolism* / Q000494:pharmacology; D002843:Chromatin / Q000378:metabolism*; D004247:DNA / Q000378:metabolism*; D004249:DNA Damage / Q000187:drug effects; D006801:Humans; D017665:Hydroxyl Radical / Q000032:analysis / Q000378:metabolism*; D008670:Metals / Q000378:metabolism* / Q000494:pharmacology
D000903:Antibiotics, Antineoplastic; D002843:Chromatin; D008670:Metals; D017665:Hydroxyl Radical; D004247:DNA