title: Culture results in open wound treatment with muscle transfer for tibial osteomyelitis.
abstract: Fifty-three patients who underwent a two-staged protocol of debridement and muscle flap coverage for chronic osteomyelitis of the tibia between 1991 and 1996 were evaluated. All patients underwent a thorough debridement of all nonviable tissue and bone at initial debridement. Multiple cultures were taken, including aerobic, anaerobic and fungal cultures from the pus, soft tissue, bone curettings and bone. All patients were treated with open wound management and dressing changes. Between 2 to 7 days, median 4 days, all patients underwent a second debridement with a complete set of identical cultures, and immediate soft tissue muscle transfer. There were 42 free vascularized and 11 local tissue transfers. The 53 patients were classified according to the Cierny-Mader classification for chronic osteomyelitis. Twenty-four patients had Stage IVA osteomyelitis, 10 patients had Stage IIIA osteomyelitis, nine patients had Stage IIIB osteomyelitis, eight patients had Stage IVB osteomyelitis, one patient had Stage IA osteomyelitis, and one patient had Stage IIB osteomyelitis. All 53 patients had positive cultures at the time of their initial debridement, and 14 of 53 (26%) had a positive culture at the time of the second debridement. Based on the results, it seems from a bacteriologic stand-point that the second debridement allows for the opportunity for redebridement and wound sterilization of organisms that still may be present.
authors: Department of Orthopaedic Surgery, University of Southern California School of Medicine, Los Angeles 90033, USA.
authors: M J
authors: MJ
authors: Patzakis
authors: N
authors: N
authors: Greene
authors: P
authors: P
authors: Holtom
authors: L
authors: L
authors: Shepherd
authors: P
authors: P
authors: Bravos
authors: R
authors: R
authors: Sherman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003646:Debridement; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000145:classification / Q000601:surgery*; D012189:Retrospective Studies; D013524:Surgical Flaps; D013977:Tibia