[Laboratory study of the cytotoxicity of colored soft contact lenses].
In the clinical practice we have met with the fact that some patients did not tolerate soft coloured contact lenses even when they used them for a short time. To find whether the cause is the composition of these lenses, mainly the adding of stain, he used the laboratory test to determine cytotoxicity, the test of dynamic observation of cytotoxicity where the cells cultured in vitro are the experimental object. On the basis of the results of this test commonly used for the determination of the cytotoxicity of implantation materials, he thinks that the cause of intolerance of coloured lenses is not their toxicity but other phenomena. An individual hypersensitivity or insufficient care of lenses (the influence of disinfectants) can be among these causes.
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Katedra biologie Lékarské fakulty Univerzity Karlovy, Hradec Králové.
D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D004396:Coloring Agents / Q000009:adverse effects* / Q000633:toxicity; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects*; D006801:Humans
D004396:Coloring Agents