IC202A, a new siderophore with immunosuppressive activity produced by Streptoalloteichus sp. 1454-19. II. Physico-chemical properties and structure elucidation.
IC202A (1) was isolated from the culture filtrate of Streptoalloteichus sp. 1454-19. The structure of 1 was determined by spectral analysis including a variety of two-dimentional NMR and FAB-MS experiments. IC202A is a ferrioxamine-related compound containing a butylidene N-oxide function.
Iijima
M
M
Institute for Chemotherapy, MCRF, Shizuoka, Japan.
Someno
T
T
Amemiya
M
M
Sawa
R
R
Naganawa
H
H
Ishizuka
M
M
Takeuchi
T
T
D000192:Actinomycetales / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D003676:Deferoxamine / Q000737:chemistry; D004578:Electron Spin Resonance Spectroscopy; D006877:Hydroxamic Acids / Q000737:chemistry*; D007166:Immunosuppressive Agents / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D017262:Siderophores / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment
D000577:Amides; D006877:Hydroxamic Acids; C118260:IC 202A; D007166:Immunosuppressive Agents; D017262:Siderophores; D003676:Deferoxamine