title: Association between histological diagnosis of Helicobacter pylori and coronary heart disease: results of a retrospective study.
abstract: OBJECTIVE
  Several epidemiological and clinical reports have investigated the relationship between Helicobacter pylori (H. pylori) infection and ischemic heart disease (IHD). All studies utilized for the diagnosis of H. pylori infection the antibody titre that is unable to distinguish an actual from a previous H. pylori infection.
  
  
  METHODS
  We report a retrospective analysis on 149 subjects, who underwent an esophago-gastro-duodenoscopy, in whom the search for H. pylori was histologically performed.
  
  
  RESULTS
  The prevalence of IHD is not significantly different from that observed in H. pylori free patients (26% vs 21%, p = 0.527).
  
  
  CONCLUSIONS
  The mechanism underlying the possible role of H. pylori needs further investigation and prospective studies to further analyze the relationship between "active" H. pylori infection and ischemic heart disease were necessary.
authors: Dipartimento di Terapia Medica, Università La Sapienza, Rome, Italy. basili@uniromal.it
authors: S
authors: S
authors: Basili
authors: M
authors: M
authors: Vieri
authors: V N
authors: VN
authors: Di Lecce
authors: D
authors: D
authors: Maccioni
authors: M
authors: M
authors: Marmifero
authors: M
authors: M
authors: Paradiso
authors: G
authors: G
authors: Labbadia
authors: S
authors: S
authors: Spada
authors: C
authors: C
authors: Cordova
authors: C
authors: C
authors: Alessandri
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D003327:Coronary Disease / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D016481:Helicobacter Infections / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D013270:Stomach / Q000382:microbiology / Q000473:pathology