Crusted scabies in two immunocompromised children: successful treatment with oral ivermectin.
Two immunodeficient children, aged 4 and 12 years, with crusted scabies were successfully treated with a single oral dose of ivermectin (200 micrograms/kg). One child had been diagnosed in infancy with an undefined congenital T cell immunodeficiency and the other with chronic mucocutaneous candidiasis. Both had failed to respond to conventional topical therapy. In view of the excellent therapeutic response and absence of side-effects, ivermectin should be considered in the treatment of recalcitrant crusted scabies in children.
Patel
A
A
Department of Dermatology, Sydney Children's Hospital, Randwick, Australia.
Hogan
P
P
Walder
B
B
D000284:Administration, Oral; D000969:Antinematodal Agents / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016867:Immunocompromised Host; D007559:Ivermectin / Q000008:administration & dosage*; D008297:Male; D012532:Scabies / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology*; D016896:Treatment Outcome
D000969:Antinematodal Agents; D007559:Ivermectin