title: Diarrhoea prevention in Bolivia through point-of-use water treatment and safe storage: a promising new strategy.
abstract: A novel water quality intervention that consists of point-of-use water disinfection, safe storage and community education was field tested in Bolivia. A total of 127 households in two periurban communities were randomized into intervention and control groups, surveyed and the intervention was distributed. Monthly water quality testing and weekly diarrhoea surveillance were conducted. Over a 5-month period, intervention households had 44% fewer diarrhoea episodes than control households (P = 0.002). Infants < 1 year old (P = 0.05) and children 5-14 years old (P = 0.01) in intervention households had significantly less diarrhoea than control children. Campylobacter was less commonly isolated from intervention than control patients (P = 0.02). Stored water in intervention households was less contaminated with Escherichia coli than stored water in control households (P < 0.0001). Intervention households exhibited less E. coli contamination of stored water and less diarrhoea than control households. This promising new strategy may have broad applicability for waterborne disease prevention.
authors: Foodborne and Diarrhoeal Diseases Branch, Division of Bacterial and Mycotic Diseases, Department of Health and Human Services, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Serv.
authors: R E
authors: RE
authors: Quick
authors: L V
authors: LV
authors: Venczel
authors: E D
authors: ED
authors: Mintz
authors: L
authors: L
authors: Soleto
authors: J
authors: J
authors: Aparicio
authors: M
authors: M
authors: Gironaz
authors: L
authors: L
authors: Hutwagner
authors: K
authors: K
authors: Greene
authors: C
authors: C
authors: Bopp
authors: K
authors: K
authors: Maloney
authors: D
authors: D
authors: Chavez
authors: M
authors: M
authors: Sobsey
authors: R V
authors: RV
authors: Tauxe
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001838:Bolivia; D002648:Child; D002675:Child, Preschool; D003256:Community Participation; D003967:Diarrhea / Q000209:etiology / Q000517:prevention & control*; D004202:Disinfectants; D005260:Female; D006266:Health Education / Q000379:methods*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D012307:Risk Factors; D014871:Water Microbiology; D018508:Water Purification / Q000379:methods*
chemical_list: D004202:Disinfectants