[The role of nitric oxide in normal and pathologic immunologic reactions].
Nitric oxide is intercellular messenger that performs a number of important functions, including neurotransmission, vasodilation, inhibition of platelet aggregation and modulation of leukocyte adhesion. The paper presents a new aspects of NO synthesis regulation by bacterial products and cytokines. Problems concerning the role of NO in antimicrobial/antitumor resistance and pathomechanisms of autoimmune diseases are also discussed.
Zdzisińska
B
B
Zakład Wirusologii i Immunologii Instytutu Mikrobiologii i Biotechnologii Uniwersytetu Marii Curie-Skłodowskiej, Lublinie.
Kandefer-Szerszeń
M
M
D015815:Cell Adhesion Molecules / Q000378:metabolism; D016207:Cytokines / Q000378:metabolism; D006801:Humans; D007962:Leukocytes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D008262:Macrophage Activation / Q000502:physiology; D009569:Nitric Oxide / Q000502:physiology*; D010974:Platelet Aggregation / Q000502:physiology; D012016:Reference Values; D009435:Synaptic Transmission / Q000502:physiology; D014664:Vasodilation / Q000502:physiology
D015815:Cell Adhesion Molecules; D016207:Cytokines; D009569:Nitric Oxide