title: [Retinol Acetate Reference Standard (Control 971) and Retinol Palmitate Reference Standard (Control 971) of National Institute of Health Sciences].
abstract: The "Retinol Acetate Reference Standard (Control 971)" and "Retinol Palmitate Reference Standard (Control 971)" of National Institute of Health Sciences using the assay of vitamin A ester were prepared. The proposed materials were evaluated in collaboration with four laboratories. Analytical data obtained were as follows. 1) The purities of retinol acetate and retinol palmitate measured by HPLC were 99.9 +/- 0.06% and 94.5 +/- 0.06%, respectively. 2) ultraviolet spectrum of retinol acetate and retinol palmitate showed the lambda max at 326-327 nm. 3) The difference in relative extinction of retinol acetate and retinol palmitate at 300 nm, 310 nm, 320 nm, 330 nm, 340 nm and 350 nm are within the range provided in JPXIII. 4) The contents of retinol acetate and retinol palmitate were 52,000 IU/g and 52,200 IU/g, respectively. Based on the above results, these proposed materials were authorized to be the Reference Standards of the National Institute of Health Sciences.
authors: tanimoto@nihs.go.jp
authors: T
authors: T
authors: Tanimoto
authors: M
authors: M
authors: Iwata
authors: A
authors: A
authors: Kitajima
authors: K
authors: K
authors: Maekawa
authors: H
authors: H
authors: Saito
authors: S
authors: S
authors: Okada
mesh_terms: D004224:Diterpenes; D006077:Government Agencies; D007564:Japan; D010602:Pharmacopoeias as Topic / Q000592:standards; D012015:Reference Standards; D012172:Retinaldehyde / Q000031:analogs & derivatives* / Q000032:analysis / Q000592:standards; D000084562:Retinyl Esters; D014801:Vitamin A / Q000031:analogs & derivatives* / Q000032:analysis / Q000592:standards
chemical_list: D004224:Diterpenes; D000084562:Retinyl Esters; C033889:retinal palmitate; D014801:Vitamin A; C009166:retinol acetate; D012172:Retinaldehyde