Genes, variation of cholesterol and fat intake and serum lipids.
Several studies have examined gene-diet interactions in the response of plasma lipid concentrations to changes in dietary fat and/or cholesterol. Among the gene loci examined, APOE has been the most studied, and the current evidence suggests that this locus might be responsible for some of the interindividual variability in dietary response. Other loci, including APOA4, APOA1 and APOB have also been found to account for some of the variability in the fasting and fed states.
Ordovas
J M
JM
Lipid Metabolism Laboratory, JM-USDA-Human Nutrition Research Centre on Ageing, Tufts University, Boston, Massachusetts 02111, USA. ordovas_li@hnrc.tufts.edu
Schaefer
E J
EJ
D001053:Apolipoproteins / Q000097:blood / Q000235:genetics; D004041:Dietary Fats / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006951:Hyperlipoproteinemias / Q000235:genetics*; D008055:Lipids / Q000097:blood*; D008297:Male
D001053:Apolipoproteins; D004041:Dietary Fats; D008055:Lipids