title: Parameters affecting cellular adhesion to polylactide films.
abstract: Absorbable biomaterials have been recently incorporated into the field of tissue engineering. Little work has been performed, even with the clinically acceptable absorbables, concerning their tissue promoting capability or lack, thereof. Furthermore, the relative attractions of cells to these implants may be largely disguised by the presence of serum. This research involved the development of an adhesion assay to compare the adhesion behavior of two cell types to two different polylactides in a serum free environment. The results showed that the attachment behavior depends not only on the cell or the polymer but a combination of the two.
authors: Department of General Surgery Research, Carolinas Medical Center, Charlotte, NC 28232-2861, USA.
authors: K J
authors: KJ
authors: Burg
authors: W D
authors: WD
authors: Holder
authors: C R
authors: CR
authors: Culberson
authors: R J
authors: RJ
authors: Beiler
authors: K G
authors: KG
authors: Greene
authors: A B
authors: AB
authors: Loebsack
authors: W D
authors: WD
authors: Roland
authors: D J
authors: DJ
authors: Mooney
authors: C R
authors: CR
authors: Halberstadt
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D002452:Cell Count; D018929:Cell Culture Techniques / Q000295:instrumentation* / Q000379:methods*; D016895:Culture Media, Serum-Free / Q000378:metabolism; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism*; D005260:Female; D005947:Glucose / Q000378:metabolism; D019344:Lactic Acid / Q000378:metabolism; D009130:Muscle, Smooth / Q000166:cytology / Q000378:metabolism*; D011091:Polyesters / Q000737:chemistry*; D051381:Rats; D013696:Temperature; D013997:Time Factors
chemical_list: D016895:Culture Media, Serum-Free; D011091:Polyesters; D019344:Lactic Acid; C033616:poly(lactide); D005947:Glucose