[Cholecalciferol Reference Standard (Control 971) of National Institute of Health Sciences].
The raw material for cholecalciferol was examined for preparation of the "Cholecalciferol Reference Standard (Control 971)". Analytical data obtained were as follows: melting point, 83.8 degrees C; UV and infrared spectra, the same as those for JP Cholecalciferol Reference Standard (Control 945), respectively; specific absorbance at 265 nm, E1 cm 1% = 485; optical rotation, [alpha]D20 = +107.4 degrees; thin-layer chromatography and high-performance liquid chromatography (HPLC), no impurity was detected; assay, 98.9% by HPLC. Based on the above results, the raw material was authorized as the Cholecalciferol Reference Standard (Control 971) of National Institute of Health Science.
Iwata
M
M
Kitajima
A
A
Maekawa
K
K
Saito
H
H
Tanimoto
T
T
Okada
S
S
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002762:Cholecalciferol / Q000032:analysis / Q000592:standards*; D006077:Government Agencies; D007564:Japan; D012015:Reference Standards
D002762:Cholecalciferol