[Values of phase-contrast microscopy in the etiological diagnosis of hematuria in adults. Part I. Establishing individual norms for glomerular hematuria].
In the cohort of 123 patients (average age 44 years) criteria for glomerular and nonglomerular hematuria (H) were established by phase-contrast microscopy (PCM). According to literature, hematuria was divided into glomerular, mixed or nonglomerular if: > 60%, 20-60% and < 20% dysmorphic erythrocytes (E) of fresh morning urine sediment were found. Diagnosis of glomerulonephritis was confirmed by renal biopsy in 54/57 glomerular H as well as in all 8 cases of mixed H. On the contrary, urological reasons for H were found in 55/58 cases of nonglomerular H with normal renal biopsy in the remaining 3 patients. Using value > 20% of dysmorphic E as a new norm for glomerular H, we found sensitivity and specificity of this test as 100% and 95% respectively.


CONCLUSIONS
glomerular H should be suspected and renal biopsy recommended when > 20% dysmorphic E are found by PCM what means exclusion of the term "mixed H".
Obroniecka
I
I
Kliniki Nefrologii ze Stacja Dializ, Centralnego Szpitala Klinicznego WAM.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005260:Female; D005921:Glomerulonephritis / Q000150:complications* / Q000175:diagnosis*; D006417:Hematuria / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D008858:Microscopy, Phase-Contrast / Q000379:methods; D008875:Middle Aged; D012189:Retrospective Studies