Potential use of microencapsulation for sustained drug delivery to the respiratory tract.
Microencapsulation has long been regarded as a means of achieving sustained drug delivery.  In these studies, a spray drying technique was used to produce salbutamol-loaded albumin microparticles with a view to formulating a controlled release system to be used in respiratory drug delivery.  Encapsulation efficiencies (40-60 % w/w) obtained using this technique compared very favourably with those obtained using emulsification procedures (1-2 % w/w).
Department of Pharmacy, King's College London, UK.
M
M
Haghpanah
C
C
Marriott
G P
GP
Martin
D000420:Albuterol / Q000138:chemical synthesis; D003692:Delayed-Action Preparations / Q000008:administration & dosage / Q000138:chemical synthesis*; D006801:Humans; D008863:Microspheres; D012138:Respiratory Therapy