Assessment of aortic regurgitation by transesophageal echocardiography: correlation with angiographic determination.
Transthoracic echocardiographic studies have shown that color Doppler mapping of the aortic regurgitation (AR) jet correlated well with the severity of regurgitation as assessed by contrast aortography.  The present study was performed to assess whether these parameters could be similarly applied to measurements determined by transesophageal echocardiography (TEE).  In order to determine and validate criteria for the assessment of AR severity, 39 clinically stable patients with a TEE color Doppler study and contrast aortography within a 2-week period were identified.  The ratio of the jet area (JA) to left ventricular diastolic area (LVDA) had the best correlation to AR severity as determined by contrast aortography (r = 0.89).  Jet length, JA, the ratio of jet width to the width of the left ventricular outflow tract and jet width had r values of 0.88, 0.88, 0.83, and 0.84, respectively. The best sensitivity and specificity for the assessment of AR by TEE were obtained as follows:  JA/LVDA ratio of 0%-7% predicts 0-1 + AR; 8%-20% 2-3 + AR, and greater than 20% 4 + AR.  Of the three patients miscategorized, none was misgraded by more than one angiographic grade of AR.  Jets that measure more than 6 cm in length or have an area of greater than 10 cm 2 have a 100% sensitivity and specificity for diagnosing 4 + AR.  In the present study the ratio of JA to LVDA area correlates best with AR severity as determined by angiography.
Echocardiography Laboratory, Division of Cardiovascular Disease, Albert Einstein Medical Center, Philadelphia, PA  19141.
C B
CB
Meyerowitz
L E
LE
Jacobs
M N
MN
Kotler
J H
JH
Wertheimer
A
A
Ioli
S
S
Janzer
K
K
Chandrasekaran
D000368:Aged; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging*; D006328:Cardiac Catheterization; D017023:Coronary Angiography / Q000379:methods / Q000706:statistics & numerical data; D015150:Echocardiography, Doppler / Q000379:methods* / Q000706:statistics & numerical data; D004947:Esophagus; D005069:Evaluation Studies as Topic; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D012680:Sensitivity and Specificity