Analysis of biomedical polymer surfaces: polyurethanes and plasma-deposited thin films.
The surface characterization of biomaterials is important for understanding the biological reactivity of surfaces and for monitoring surface reproducibility and contamination.  Electron spectroscopy for chemical analysis (ESCA), secondary ion mass spectrometry (SIMS), contact-angle methods, vibrational spectroscopic methods, and scanning probe microscopies are briefly reviewed.  Examples are presented using these methods to characterize RF plasma-deposited surfaces based upon acetone and oxygen for cell culture and Biomer¿ surfaces.
Ratner
B D
BD
Department of Chemical Engineering and Center for Bioengineering, University of Washington, Seattle, 98195.
Tyler
B J
BJ
Chilkoti
A
A
D001672:Biocompatible Materials; D004577:Electron Probe Microanalysis / Q000379:methods; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods; D008422:Materials Testing / Q000379:methods*; D016252:Microscopy, Scanning Tunneling / Q000379:methods; D011140:Polyurethanes / Q000737:chemistry*; D013055:Spectrophotometry, Infrared / Q000379:methods; D013499:Surface Properties