Determining the formulary status of quinolone antibiotics: one institution's approach.
Streamlining antibiotic therapy--ie, simplifying regimens, route of administration, or both--is necessary in the modern treatment of hospitalized patients with infectious diseases. Due to their pharmacokinetic profiles and comparative efficacy and safety, the quinolone class of antibiotics is an ideal class for which to direct streamlining efforts. Including only one agent of this class on the formulary, however, is inadequate. Having several quinolones available, and thus expanding the local hospital market for them, enables more physicians to be contacted and educated by manufacturers' sales representatives as part of the hospital's antibiotic management program. By assisting in the education efforts, pharmaceutical representative help to conserve hospital resources, both in terms of cost and personnel. In addition, having more than one supplier of quinolones encourages competition, which favors price reductions.
Hartford Hospital, CT 06115.
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Nightingale
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Lubowski
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Quintiliani
D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000191:economics / Q000493:pharmacokinetics; D003237:Connecticut; D003657:Decision Making; D016527:Drug Costs; D005572:Formularies, Hospital as Topic; D006801:Humans; D007239:Infections / Q000188:drug therapy*; D010606:Pharmacy and Therapeutics Committee; D015363:Quinolones / Q000008:administration & dosage* / Q000191:economics / Q000493:pharmacokinetics