Allografting in total knee replacement arthroplasty.
Revision, and complicated primary total knee arthroplasty (TKA), may present with significant structural bony defects.  Allograft offers blocks of material that can be shaped to the defect.  The opportunity to gain a biological bond may theoretically enhance loading conditions and enhance any subsequent surgery.  However, the biomechanical and biological issues of immune response, infection, graft incorporation, resorption, and load transfer render allografting a powerful but problematic technology.
Hospital for Joint Diseases, Orthopaedic Institute, New York 10003.
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D000328:Adult; D016025:Bone Transplantation / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D007720:Knee Prosthesis / Q000379:methods*; D012086:Reoperation; D013314:Stress, Mechanical; D013530:Surgical Wound Infection / Q000209:etiology; D014184:Transplantation, Homologous