Effect of filtration, storage and platelet suspension media on platelet indices.
We describe a new approach for assessing filtration-induced changes in cellular indices of platelet concentrates at the beginning and the end of storage, using pairs of identical packs. The results revealed that post-filtered products did not store as well as their counterparts.  Filtration did not induce any significant changes on aggregation as determined by spontaneous aggregation nor was there a disparity between leucocyte peroxidase/basophil count.  We recommend filtration on day 2 which causes minimal loss of platelets and less change in the mean platelet volume.
Department of Laboratory Medicine, Chulalongkorn University Hospital, Bangkok, Thailand.
P
P
Krailadsiri
J
J
Seghatchian
D001792:Blood Platelets / Q000166:cytology*; D001793:Blood Preservation; D005069:Evaluation Studies as Topic; D005374:Filtration / Q000379:methods*; D006801:Humans; D015539:Platelet Activation