A critique of pancreas transplantation.
There are three possible indications for pancreas transplantation 1. to correct the diabetic state; 2. to cure or ameliorate the complications of diabetes or to delay or diminish their deterioration; 3. to prevent the complications.  The diabetes we are considering here is type 1 or insulin-dependent diabetes, a disorder in which there is more or less complete insulin deficiency.  No one has suggested pancreas transplantation for type 2, non-insulin dependent diabetes. This article questions the rationale of pancreas transplantation.  It maintains that the value of the procedure has not been established.
Diabetic Dept., King's College Hospital, London, U.K.
D A
DA
Pyke
D003362:Cost-Benefit Analysis; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000601:surgery*; D006801:Humans; D016035:Pancreas Transplantation / Q000009:adverse effects / Q000639:trends