Studies on peri-root tissue formation around new type artificial root made of dense hydroxyapatite.
The aim of this study was to examine the wound healing process and tissue development around a new type of artificial root made of dense hydroxyapatite.  The newly tailored artificial roots, which have characteristic corrugated configurations with smooth root surfaces, were implanted immediately after extraction of the premolars of adult dogs.  After preliminary experiments, the following studies were carried out:  for the observation of tissue formation around the artificial root, artificial root with surrounding tissue were extirpated after fixed periods (6-32 weeks) of implantation; to study tissue formation at the artificial root surface, undecalcified specimens with polished surfaces for microanalysis and decalcified specimens for light microscopic observation were prepared after 72 weeks of implantation.  The following results were obtained:  around the artificial roots in the jawbone, fibrous tissue formation with angled orientation, bone formation resembling alveolar bone proper, and calcified substance formation attaching to the root surface were observed.
Nishihara
K
K
Department of Oral Surgery, Faculty of Medicine, University of Tokyo, Japan.
D000818:Animals; D001861:Bone Regeneration / Q000502:physiology*; D015921:Dental Implants; D004285:Dogs; D006882:Hydroxyapatites / Q000737:chemistry*; D008297:Male; D008422:Materials Testing; D014092:Tooth Root / Q000098:blood supply / Q000502:physiology*; D014945:Wound Healing / Q000502:physiology