Heart failure: clinical implications of recent trials.
The frustration has been in identifying drugs that have a positive impact on cardiac performance and a negative effect on mortality. ACE inhibitors, often with diuretics and possibly with digoxin, continue to show impressive outcomes in major studies.
Pitt
B
B
Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, USA.
Nicklas
J M
JM
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D002316:Cardiotonic Agents / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D011719:Pyrazines; D011804:Quinolines / Q000627:therapeutic use