Critical leg ischaemia in New Zealand: economic cost of amputation versus intravenous iloprost.
The purpose of this study was to establish the incidence of surgical amputation for critical leg ischaemia in New Zealand, and estimate the hospital, prostheses and indirect costs of this intervention.  The cost of amputations was then compared with the cost of treating such patients with iloprost.  The study was retrospective.  Individual patient records relating to 1991 for both public and private hospitals were analysed.  Unit costs relevant to 1991 were applied to the volume data of patients and procedures to derive total costs.  Costs were estimated on an incremental basis taking a societal perspective.  Conservative estimates were obtained for hospital costs, prostheses and for production loss (loss of output or productivity).  Total cost was $NZ15.9 million (hospital and prosthesis cost $NZ13.1 million, production loss $NZ2.8 million).  The total quantified cost per amputation was $NZ23 038 (hospital and prosthesis cost $NZ19 020, production loss $NZ4017).  32% of patients requiring amputations were in the working age group.  The theoretical avoidance of amputation by treatment with iloprost resulted in net savings of hospital and prosthetic costs of between $NZ6660 and $NZ8720 per patient.  Amputation for critical leg ischaemia is costly and has a high mortality, but for iloprost treatment to be cost effective in a New Zealand hospital setting, patients must be targeted and a success rate of at least 55% achieved in avoidance of amputation and reduction of pain while at rest.
W. Guy Scott and Associates Ltd, Wellington, New Zealand.
H M
HM
Scott
W G
WG
Scott
D000671:Amputation, Surgical / Q000191:economics; D001186:Artificial Limbs / Q000191:economics; D017281:Cost of Illness; D003362:Cost-Benefit Analysis; D003953:Diagnosis-Related Groups; D017721:Hospital Costs; D006801:Humans; D016285:Iloprost / Q000191:economics / Q000627:therapeutic use; D015994:Incidence; D007511:Ischemia / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery; D007866:Leg; D009520:New Zealand; D016491:Peripheral Vascular Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery; D012189:Retrospective Studies