Comparing drugs for short-term sedation.
Selected benzodiazepines and a phenol derivative are reviewed in relation to their appropriateness as short-term sedatives in settings such as noninvasive and invasive medical procedures. Terminating sedation with flumazenil is also a focus of interest.
Larson
J S
JS
Department of Anesthesiology, Mayo Clinic, Scottsdale, Ariz., USA.
Lunn
J J
JJ
D000758:Anesthesia; D001569:Benzodiazepines / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D016292:Procedural Sedation / Q000009:adverse effects / Q000379:methods; D003975:Diazepam / Q000493:pharmacokinetics / Q000627:therapeutic use; D005442:Flumazenil / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D008140:Lorazepam / Q000493:pharmacokinetics / Q000627:therapeutic use; D008874:Midazolam / Q000493:pharmacokinetics / Q000627:therapeutic use; D010146:Pain / Q000188:drug therapy; D015742:Propofol / Q000493:pharmacokinetics / Q000627:therapeutic use