Heart failure: clinical implications of recent trials.
The frustration has been in identifying drugs that have a positive impact on cardiac performance and a negative effect on mortality. ACE inhibitors, often with diuretics and possibly with digoxin, continue to show impressive outcomes in major studies.
Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, USA.
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D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D002316:Cardiotonic Agents / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D011719:Pyrazines; D011804:Quinolines / Q000627:therapeutic use