Role of magnetic resonance imaging (MRI) in detecting liver changes after gallstone extracorporeal shock wave lithotripsy (ESWL).
Recently published literature on biliary extracorporeal shock wave lithotripsy (ESWL) has shown that high-energy ESWL utilizing high kV is more effective than the low-energy ESWL and low kV used previously. Prior studies have not reported injury to the gallbladder or adjacent liver following ESWL. Our study evaluated 29 patients that were treated with high kV ESWL. Magnetic resonance imaging (MRI) was used to study the gallbladder and adjacent liver for possible injury resulting from the high-energy treatment.  The patients, selected using the Dornier MPL-9000 United States protocol, underwent ESWL using 18-24 kV (average 21 kV).  MRI was done both pre and post-ESWL in all 29 patients.  Ten patients had a second treatment to reduce fragment size and, subsequently, had an additional MRI examination.  Spin echo MRI images were obtained at the level of the gallbladder fossa using a 0.5-Tesla ESATOM RM 5000 (ESAOTE Biomedica, Genva, Italy.) superconductive unit.  Both T1- and T2-weighted images were obtained.  In 26 patients the hepatic parenchyma was normal post-ESWL.  Two patients had a hyperintense region on T1-weighted images post-ESWL that was felt to be related to pericholecystic fat.  A third patient had an abnormality detected on T2-weighted images that was thought to be due to hepatic edema or microhemorrhage.  No significant changes were shown by laboratory or concurrent ultrasound examinations.  Repeat MRI examinations in these three patients were normal.  High-energy ESWL appears as safe as low-energy ESWL in the treatment of patients with symptomatic gallstones.
Lomanto
D
D
II Clinica Chirugica, University of "La Sapienza," Rome, Italy.
Pavone
P
P
Torres
W E
WE
Nardovino
M
M
Giuliani
S
S
Lezoche
E
E
Speranza
V
V
Passariello
R
R
D000328:Adult; D000368:Aged; D002769:Cholelithiasis / Q000628:therapy*; D004869:Equipment Safety; D005260:Female; D006801:Humans; D008096:Lithotripsy / Q000009:adverse effects* / Q000379:methods; D008111:Liver Function Tests; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome