The characterisation of inhalation devices by an inhalation simulator: The Electronic Lung.
The Electronic Lung is an inhalation simulator designed for the characterisation of breath-actuated inhalation devices. It enables the in-vitro evaluation of devices under conditions that have been produced in-vivo. Data generated on the Serevent Diskhaler inhaler have highlighted the reproducibility of particle size distribution of drug delivered from the device over a range of inhalation parameters.
Brindley
A
A
Department of Respiratory Product Development, Glaxo Group Research Ltd., Hertfordshire, UK.
Sumby
B S
BS
Smith
I J
IJ
D003198:Computer Simulation; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D006801:Humans; D008962:Models, Theoretical; D009330:Nebulizers and Vaporizers