Evaluation of wear in an all-polymer total knee replacement.  Part 2: clinical evaluation of wear in a polyethylene on polyacetal total knee.
In an effort to improve the long-term result of total joint replacement arthroplasty, we have investigated the use of a polymer-on-polymer articular replacement arthroplasty.  Because of their known biocompatibility and previous use in orthopedic surgery, polyethylene and polyacetal (copolymer, Hoechst) were selected.  Polyethylene served in its usual role as the concave member of the articulation; polyacetal formed the convex number.  Formal wear testing using a multi-channel hip simulator demonstrated superior wear characteristics of the polymer-on-polymer configuration compared to a conventional chrome-cobalt versus polymer (polyethylene) configuration. A clinical series of relatively high-activity patients having a minimum five-year follow-up (N = 26) showed no specific unfavorable reaction to this material combination in a total knee replacement.  Given certain potential advantages of polymeric materials, as well as some theoretical disadvantages of metallic materials, a polymer-on-polymer design for a large joint replacement may have some merit.
Bradley
G W
GW
Freeman
M A
MA
Tuke
M A
MA
McKellop
H A
HA
D000080:Acetals / Q000737:chemistry*; D002858:Chromium Alloys / Q000737:chemistry; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008422:Materials Testing; D011108:Polymers / Q000737:chemistry*; D011475:Prosthesis Failure