Some characteristics of new DNA-bearing plasmoimmunoadsorbents based on fibrous activated carbon.
A new dual adsorbent containing from 1 to 8 mg of native or denatured thymic DNA per 1 g of the fibrous activated carbon matrix has demonstrated sufficient biocompatibility and good selectivity for DNA-binding plasma substances. At the same time, this dual adsorbent exhibits a full scale of coupling modalities characteristic of the highest quality activated carbons. All these features of DNA-coated fibrous activated carbons allow them to be considered as promising plasmosorbents for the treatment of numerous immuno-dependent diseases and metabolic disorders.
Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, Academy of Sciences of Ukraine, Kiev.
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Snezhkova
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Nikolaev
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Sergeev
D001672:Biocompatible Materials; D002244:Carbon; D004247:DNA; D006801:Humans; D007163:Immunosorbent Techniques; D007164:Immunosorbents