The prehospital use of albuterol inhalation treatments.
The use of bronch odilators in the prehospital EMS setting is common.  This study examined the safety of the administration of 2.5 mg albuterol using a hand-held nebulizer for the treatment of such patients.  A total of 55 patients were included.  Following treatment, peak expiratory flow rates (PEFR) increased a mean of 27 L/min, ventilatory rate decreased four breaths/min, heart rate decreased slightly, and systolic blood pressure increased 10 mmHg.  Five of the 53 patients in whom cardiac rhythm was monitored, had premature ventricular complexes prior to treatment; only one did following therapy.  Breath sounds improved in 61% and were unchanged in 39%.  Breathing was reported by the patient as improved in 51 of the 53 (93%) and only one felt worse.  Adverse reactions were reported in 15%, but none were severe.  This study shows that albuterol (2.5 mg) administration by hand-held nebulizer is both safe and efficacious in the prehospital setting.
Vonderohe
E A
EA
Wright State University School of Medicine, Dayton, Ohio.
Jones
J H
JH
McGrath
R B
RB
Bell
L H
LH
D000280:Administration, Inhalation; D000420:Albuterol / Q000009:adverse effects / Q000627:therapeutic use*; D001794:Blood Pressure; D004632:Emergency Medical Services; D006339:Heart Rate; D006801:Humans; D009330:Nebulizers and Vaporizers; D010366:Peak Expiratory Flow Rate