Pressure ulcers: critical considerations in prevention and management.
Pressure ulcer development is a serious problem occurring predominately among elderly persons, who are confined to bed or chair.  Factors associated with pressure ulcer development include: cerebrovascular accident, impaired nutritional intake, fecal incontinence, lymphocytopenia and a high comorbidity score.  Implementation of preventative measures, such as: in-depth assessment for mobility, a pressure relieving device combined with adequate repositioning, thorough evaluation for nutritional status and urinary incontinence, significantly reduce pressure ulcer incidence. If the pressure ulcer is a partial thickness (Stage II) wound, the causative factors are probably friction and/or moisture.  If the ulcer is full thickness (Stage III, IV) it is secondary to pressure and/or shearing forces.  The development of wound infection is the most common complication.  Osteomyelitis is not an uncommon occurrence and must be initially ruled out in all full thickness pressure ulcers.  Surgical debridement of necrotic tissue is necessary prior to further treatment and /or assessments.  Cultures and antibiotic therapy are indicated only upon evidence of infection (erythema, edema, cellulitis, osteomyelitis, leukocytosis, bandemia or fever). Topical pharmacologic agents may be used to prevent or treat infection but must be carefully controlled to avoid such adverse effects as toxicity to the wound, allergic reaction and development of resistant pathogens.  Proper use of occlusive dressings increase patient comfort, enhance healing, decrease the possibility of infection, save time and reduce costs.  A patient presenting an ulcer which fails to improve, or due to its size will take a great deal of time to heal, should be evaluated for surgical closure.
Alvarez
O M
OM
University Wound Healing Clinic, New Brunswick, New Jersey.
D000368:Aged; D000818:Animals; D001513:Beds; D006801:Humans; D009779:Occlusive Dressings; D010019:Osteomyelitis / Q000209:etiology; D003668:Pressure Ulcer / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000517:prevention & control / Q000628:therapy; D012307:Risk Factors