Effectiveness of bromochlorophene on gingival health.
The effect of a commercial toothpaste containing 0.2% bromochlorophene (BCP) on established plaque and gingivitis was compared with placebo. The two toothpastes were similar in packaging, taste, consistency, and color. Thirty-two patients with chronic gingivitis were enrolled in this randomized, double-blind comparison and were asked to brush twice a day with the given toothpaste without changing their oral hygiene habits. Plaque index, gingival index, gingival crevicular fluid, and papillary bleeding index were recorded at baseline and after 3 weeks. Significant decreases in gingival and papillary bleeding indices were noted in the BCP group, as compared with the placebo group. Plaque index significantly decreased in both groups. No significant change was noted in the volume of gingival crevicular fluid.
Department of Periodontology School of Dental Medicine and Stomatology Catholic University of Louvain Brussels, Belgium.
P
P
Bercy
Y
Y
Flamand
P
P
Defleur
D000470:Alkaloids / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001559:Benzhydryl Compounds / Q000627:therapeutic use*; D053119:Benzophenanthridines; D003773:Dental Plaque; D005260:Female; D005891:Gingivitis / Q000188:drug therapy*; D006801:Humans; D007546:Isoquinolines; D008297:Male; D014260:Triclosan / Q000627:therapeutic use*