Conversion of treatment from cefoxitin to ampicillin/sulbactam: experience in a university teaching hospital.
A 12-month trial, conducted in a 650-bed university teaching hospital, evaluated the conversion from cefoxitin to ampicillin/sulbactam. This report discusses the methodology used to evaluate the feasibility of the change and the challenges encountered during the trial period. The effect of cost and overall therapeutic outcome were other aspects of the evaluation. Results indicate that a conversion from cefoxitin to ampicillin/sulbactam is not only feasible but is also a realistic approach to achieving high-quality, cost-effective care.
Erie County Medical Center Buffalo, New York, USA.
J G
JG
Kitrenos
D L
DL
Rotella
S
S
Nakasato
D000667:Ampicillin / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy*; D002440:Cefoxitin / Q000627:therapeutic use*; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D006785:Hospitals, University; D006801:Humans; D013407:Sulbactam / Q000627:therapeutic use