Clinical implications of visceral hyperalgesia.
Based on clinical experience and our understanding of chronic pain, both affective and sensory pathways may be involved in the visceral hyperalgesia seen in most patients with functional bowel disorders. This new awareness has changed the focus of treatment.
Mayer
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EA
VA Wadsworth Medical Center, Los Angeles, USA.
D003109:Colonic Diseases, Functional / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D004032:Diet / Q000009:adverse effects; D004064:Digestive System / Q000294:innervation* / Q000503:physiopathology*; D005759:Gastroenteritis / Q000150:complications; D005767:Gastrointestinal Diseases / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D005769:Gastrointestinal Motility / Q000502:physiology; D006801:Humans; D006930:Hyperalgesia / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D012307:Risk Factors; D013312:Stress, Physiological / Q000150:complications; D014781:Viscera; D017833:Visceral Afferents / Q000502:physiology