Dextranomer (Debrisan) paste in post-operative wounds.  A controlled study.
The clinical effect of dextranomer paste (Debrisan) in post-operative wounds (20 patients) was compared with the standard treatment in our department (polyvinylpyrrolidone, 20 patients) in a randomized study. All variables dealing with cleansing, inflammation-reducing effect and signs of ongoing healing were studied. Dextranomer paste appeared to be significantly better than polyvinylpyrrolidone in wounds with a high degree of pus and debris. No side-effects were observed in the dextranomer paste group.  One patient in the control group showed an allergic reaction (oedema and erythema) and was withdrawn from the study.
Surgical Department, Academische Ziekenhuizen St Rafaël en St Pieter, Katholieke Universiteit Leuven, Belgium.
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I
Michiels
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MR
Christiaens
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003646:Debridement; D003911:Dextrans / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments; D011205:Povidone / Q000008:administration & dosage / Q000627:therapeutic use; D013492:Suppuration / Q000188:drug therapy; D013530:Surgical Wound Infection / Q000188:drug therapy*; D014945:Wound Healing / Q000187:drug effects*