Dextranomer (Debrisan) paste in post-operative wounds.  A controlled study.
The clinical effect of dextranomer paste (Debrisan) in post-operative wounds (20 patients) was compared with the standard treatment in our department (polyvinylpyrrolidone, 20 patients) in a randomized study. All variables dealing with cleansing, inflammation-reducing effect and signs of ongoing healing were studied. Dextranomer paste appeared to be significantly better than polyvinylpyrrolidone in wounds with a high degree of pus and debris. No side-effects were observed in the dextranomer paste group.  One patient in the control group showed an allergic reaction (oedema and erythema) and was withdrawn from the study.
Michiels
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Surgical Department, Academische Ziekenhuizen St Rafaël en St Pieter, Katholieke Universiteit Leuven, Belgium.
Christiaens
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MR
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003646:Debridement; D003911:Dextrans / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments; D011205:Povidone / Q000008:administration & dosage / Q000627:therapeutic use; D013492:Suppuration / Q000188:drug therapy; D013530:Surgical Wound Infection / Q000188:drug therapy*; D014945:Wound Healing / Q000187:drug effects*