Plasma exchange for Refsum's disease.
Five patients with Refsum's disease were treated by plasma exchange. Lowering the plasma phytanic acid by plasma exchange in patients acutely ill with Refsum's disease produced clinical improvement. Plasma exchange is indicated in Refsum's disease when there is a worsening clinical condition.  Occasionally, failure of dietary control of Refsum's disease may necessitate plasma exchange.
Gibberd
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Department of Neurology, Westminster Hospital, London, U.K.
D006801:Humans; D010831:Phytanic Acid / Q000378:metabolism / Q000493:pharmacokinetics; D010951:Plasma Exchange / Q000379:methods*; D012035:Refsum Disease / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*