title: Results of balloon aortic valvuloplasty in patients with aortic stenosis associated with significant aortic regurgitation.
abstract: The influence of balloon aortic valvuloplasty (BAV) on aortic regurgitation (AR) in patients with severe aortic stenosis associated with greater than or equal to grade II AR was studied by supraaortic angiogram before and after BAV.  The results of 50 patients aged 72 +/- 12 years with significant AR before BAV (group A) were compared to 297 patients (mean age 76 +/- 10 years) with no or mild AR (group B).  In group A, the patients had a higher left ventricular end diastolic volume (96 +/- 19 mL/m 2 vs 81 +/- 32 mL/m 2, P less than 0.01) and left ventricular end diastolic pressure (23 +/- 9 mmHg vs 19 +/- 9 mmHg, P less than 0.01).  The aortic valve area was similar in both groups.  Following BAV, the improvement in aortic valve area and hemodynamics were similar in both groups. In group A, AR remained unchanged in 31 patients (62%), increased by 1 grade in 13 patients (26%), and decreased by 1 grade in 6 patients (12%).  In group B, AR increased by greater than 1 grade in 34 patients (11%) and greater than 2 grades in 4 patients (1.3%) post-BAV.  Two patients in group B underwent emergency aortic valve replacement following BAV because of severe acute AR.  In conclusion, when it is indicated, BAV can be performed with similar risk in patients with significant AR.
authors.affiliation: Service de Cardiologie, Hôpital Charles Nicolle, Centre Hospitalo-Universitaire, Rouen, France.
authors.forename: R
authors.initials: R
authors.lastname: Koning
authors.forename: C
authors.initials: C
authors.lastname: Asselin
authors.forename: N
authors.initials: N
authors.lastname: Saoudi
authors.forename: C
authors.initials: C
authors.lastname: Chan
authors.forename: G
authors.initials: G
authors.lastname: Derumeaux
authors.forename: A
authors.initials: A
authors.lastname: Cribier
authors.forename: B
authors.initials: B
authors.lastname: Letac
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001022:Aortic Valve Insufficiency / Q000628:therapy; D001024:Aortic Valve Stenosis / Q000145:classification / Q000628:therapy*; D002404:Catheterization / Q000379:methods* / Q000706:statistics & numerical data; D016009:Chi-Square Distribution; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome