Efficacy of nebulized albuterol and cromolyn sulfate for acute wheezing and stridor in children: a prospective, randomized study.
A number of respiratory tract illnesses may produce acute wheezing and stridor in children, and treatment may vary, depending on the specific illness. These illnesses, however, may be difficult to differentiate solely on clinical grounds. A uniform therapeutic approach for children with acute wheezing or stridor independent of the specific etiology can be employed. In this prospective study, 246 children received aerosolized albuterol and cromolyn sulfate. Children who remain in distress after aerosolized medications should be admitted to the hospital. Those with partial improvement may be treated with home aerosol treatments after intramuscular injection of dexamethasone.
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D000293:Adolescent; D000336:Aerosols; D000420:Albuterol / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D004205:Cromolyn Sodium / Q000008:administration & dosage / Q000031:analogs & derivatives*; D003907:Dexamethasone / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012135:Respiratory Sounds / Q000187:drug effects*; D012140:Respiratory Tract Diseases / Q000188:drug therapy*