title: The glycocalyx, biofilm, microbes, and resistant infection.
abstract: Biomaterial implants, traumatized tissues and bone are susceptible to immediate and delayed infections because microbes preferentially adhere to "inert biomaterials" or to damaged tissue surfaces. This type of infection is resistant to antibiotic therapy and most often requires removal of the prosthesis or infected tissue. This article discusses glycocalyx, biofilm, microbes, and resistant infection in prosthesis or infected tissue.
authors.affiliation: Medical Sciences Research Institute, Herndon, VA 22070, USA.
authors.forename: A G
authors.initials: AG
authors.lastname: Gristina
authors.forename: Y
authors.initials: Y
authors.lastname: Shibata
authors.forename: G
authors.initials: G
authors.lastname: Giridhar
authors.forename: A
authors.initials: A
authors.lastname: Kreger
authors.forename: Q N
authors.initials: QN
authors.lastname: Myrvik
mesh_terms: D001422:Bacterial Adhesion; D001424:Bacterial Infections / Q000503:physiopathology*; D001672:Biocompatible Materials; D018441:Biofilms; D006801:Humans; D016459:Prosthesis-Related Infections / Q000382:microbiology / Q000503:physiopathology