title: Biomechanical and clinical performance of a new synthetic monofilament absorbable suture.
abstract: The clinical and mechanical performance of a new, monofilament, synthetic absorbable suture (Biosyn) was evaluated and compared to that of a braided synthetic absorbable suture (Vicryl). The monofilament synthetic absorbable suture was significantly stronger than the braided synthetic absorbable suture over the 4 weeks of implantation. In addition, the monofilament suture potentiated less bacterial infection than did the braided suture. The handling characteristics of the monofilament suture were superior to the braided suture because the monofilament suture required fewer throws to achieve knot security, encountered lower drag forces in fascia and colon, and had a greater double-wrapped first-throw knot security. Evaluated independently in clinical settings, the monofilament sutures were found to have excellent strength, first-throw hold, knot security, passage through tissue, knot repositioning, and ease of handling.
authors.affiliation: Department of Plastic Surgery, University of Virginia School of Medicine, Charlottesville, USA.
authors.forename: G T
authors.initials: GT
authors.lastname: Rodeheaver
authors.forename: K A
authors.initials: KA
authors.lastname: Beltran
authors.forename: C W
authors.initials: CW
authors.lastname: Green
authors.forename: B C
authors.initials: BC
authors.lastname: Faulkner
authors.forename: B M
authors.initials: BM
authors.lastname: Stiles
authors.forename: G W
authors.initials: GW
authors.lastname: Stanimir
authors.forename: H
authors.initials: H
authors.lastname: Traeland
authors.forename: G M
authors.initials: GM
authors.lastname: Fried
authors.forename: H C
authors.initials: HC
authors.lastname: Brown
authors.forename: R F
authors.initials: RF
authors.lastname: Edlich
mesh_terms: D000009:Abdominal Muscles / Q000601:surgery; D000818:Animals; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D062109:Dermatologic Surgical Procedures; D004146:Dioxanes; D005260:Female; D005831:Genital Diseases, Female / Q000601:surgery; D006622:Hip Prosthesis; D006801:Humans; D051379:Mice; D011098:Polyglactin 910; D011108:Polymers; D011446:Prospective Studies; D051381:Rats; D017207:Rats, Sprague-Dawley; D013203:Staphylococcal Infections / Q000503:physiopathology; D013530:Surgical Wound Infection / Q000382:microbiology; D013536:Suture Techniques; D013537:Sutures; D013552:Swine; D013718:Tensile Strength