title: Vortex pumping for routine cardiac surgery: a comparative study.
abstract: Vortex pumping has become popular for mechanical assist applications, but has only recently received serious consideration for use as the arterial pump of choice for routine open-heart surgery.  We report on a prospective randomized study designed to evaluate this pump in routine use.  Sixteen patients undergoing routine coronary artery surgery were randomized into two groups in which the only difference in equipment and technique was the use of a Stockert roller pump in group S and a Biomedicus vortex pump in group B.  The groups were compared with respect to haematology, perioperative fluid balance, transfusion requirements, complement activation, haemolysis and microbubble transmission.  The groups were reasonably well matched, with slightly longer mean bypass and ischaemic times in group S (94.8 vs 105.5 minutes and 75.7 and 83.8 minutes respectively).  Group B patients showed significant improvements over group S patients with respect to preservation of platelet numbers, decreased complement activation and reduced microbubble transmission.  The afterload sensitivity of the vortex pump did not present the perfusionist with any practical problems although a different technique is required for initiating and terminating bypass.  We conclude that vortex pumping would seem to offer better blood handling for routine use.  More extensive testing is required to establish whether or not this would be reflected in clinically measurable improved patient outcome.
authors.affiliation: Papworth Hospital, Cambridge, UK.
authors.forename: D R
authors.initials: DR
authors.lastname: Wheeldon
authors.forename: D W
authors.initials: DW
authors.lastname: Bethune
authors.forename: R D
authors.initials: RD
authors.lastname: Gill
mesh_terms: D000328:Adult; D000368:Aged; D001157:Arterial Occlusive Diseases / Q000601:surgery; D003167:Complement Activation; D003176:Complement C3 / Q000378:metabolism; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D005112:Extracorporeal Circulation / Q000295:instrumentation*; D006355:Heart-Lung Machine; D006801:Humans; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D011446:Prospective Studies; D012189:Retrospective Studies; D012501:Saphenous Vein / Q000637:transplantation