title: Corrosion protection of metal implants by hard biocompatible ceramic coatings deposited by radio-frequency sputtering.
abstract: Most metals used for orthopaedic and stomatology implants and prostheses belong to the families of titanium or nickel-based and cobalt-based superalloys designed for advanced technology industries (e.g. space, aeronautic and nuclear industries).  Ideal materials should be as insoluble and biologically compatible as possible. In the present paper the corrosion behaviour of Ni-Cr and Co-Cr alloys in biological media is evaluated through potentiodynamic polarization tests.  It is shown that these metals exhibit some minor release of the component elements and degradation products, which may induce cytotoxic and allergic effects.  The corrosion resistance of these alloys can be strongly enhanced by hard ceramic coatings deposited by radio-frequency sputtering.  The biocompatibility of coated and uncoated metals is compared from differentiated human cell cultures.
authors.affiliation: Laboratoire de Physique des Matériaux, Meudon, France.
authors.forename: C
authors.initials: C
authors.lastname: Sella
authors.forename: J C
authors.initials: JC
authors.lastname: Martin
authors.forename: J
authors.initials: J
authors.lastname: Lecoeur
authors.forename: J P
authors.initials: JP
authors.lastname: Bellier
authors.forename: M F
authors.initials: MF
authors.lastname: Harmand
authors.forename: A
authors.initials: A
authors.lastname: Naji
authors.forename: J P
authors.initials: JP
authors.lastname: Davidas
authors.forename: A
authors.initials: A
authors.lastname: Le Chanu
mesh_terms: D002858:Chromium Alloys / Q000737:chemistry / Q000633:toxicity; D003035:Cobalt / Q000737:chemistry / Q000633:toxicity; D003343:Corrosion; D006801:Humans; D008422:Materials Testing; D016876:Metal Ceramic Alloys / Q000737:chemistry* / Q000633:toxicity; D008855:Microscopy, Electron, Scanning; D008982:Molybdenum / Q000737:chemistry / Q000633:toxicity; D009532:Nickel / Q000737:chemistry / Q000633:toxicity; D010949:Plasma; D019736:Prostheses and Implants; D012463:Saliva; D014025:Titanium / Q000737:chemistry / Q000633:toxicity