Anaphylactoid reaction to adenosine.
Adenosine (Adenocard) is an endogenous purine nucleoside that has been approved recently for intravenous treatment of paroxysmal supraventricular tachycardia. With a serum half-life of 10 seconds, reported side effects including facial flushing, dyspnea, and chest pressure are common, but very transient. An elderly woman who received adenosine for paroxysmal supraventricular tachycardia had a prolonged anaphylactoid reaction that required pharmacological treatment. This is the first reported case of a prolonged anaphylactoid reaction to adenosine.
Fata
J G
JG
Department of Medicine, Michigan State University, College of Human Medicine, Lansing, USA.
Roth
R N
RN
Carpenter
L
L
D000241:Adenosine / Q000009:adverse effects* / Q000627:therapeutic use; D000707:Anaphylaxis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013614:Tachycardia, Paroxysmal / Q000188:drug therapy; D013617:Tachycardia, Supraventricular / Q000188:drug therapy