title: Anaphylactoid reaction to adenosine.
abstract: Adenosine (Adenocard) is an endogenous purine nucleoside that has been approved recently for intravenous treatment of paroxysmal supraventricular tachycardia. With a serum half-life of 10 seconds, reported side effects including facial flushing, dyspnea, and chest pressure are common, but very transient. An elderly woman who received adenosine for paroxysmal supraventricular tachycardia had a prolonged anaphylactoid reaction that required pharmacological treatment. This is the first reported case of a prolonged anaphylactoid reaction to adenosine.
authors.affiliation: Department of Medicine, Michigan State University, College of Human Medicine, Lansing, USA.
authors.forename: J G
authors.initials: JG
authors.lastname: Fata
authors.forename: R N
authors.initials: RN
authors.lastname: Roth
authors.forename: L
authors.initials: L
authors.lastname: Carpenter
mesh_terms: D000241:Adenosine / Q000009:adverse effects* / Q000627:therapeutic use; D000707:Anaphylaxis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013614:Tachycardia, Paroxysmal / Q000188:drug therapy; D013617:Tachycardia, Supraventricular / Q000188:drug therapy