title: Infections, inflammations, and immune-mediated orbital disease.
abstract: In recent months, many authors have described distinct surgical approaches to orbital decompression in thyroid ophthalmopathy. Comparison of outcomes data should allow the surgeon to decide on the best approach to orbital decompression in an individual patient. Patients with thyroid-associated lid retraction may also benefit from approaches that allow for postoperative suture adjustment, because alignment of the lids can be particularly challenging in these patients. The clinical evaluation of patients with thyroid disease has evolved with the recognition that magnetic resonance T2 relaxation time prolongation may correlate with an inflammatory disease phase and, perhaps, with improved response to medical management. Medical management of orbital inflammation and infection should be tailored to the specific disease process and, in many cases of infection, to the age of the patient.
authors.affiliation: University of California at San Francisco, Department of Ophthalmology 94143-0730, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: O'Brien
mesh_terms: D000293:Adolescent; D000328:Adult; D009877:Endophthalmitis / Q000209:etiology* / Q000628:therapy; D015817:Eye Infections / Q000209:etiology* / Q000628:therapy; D005141:Eyelid Diseases / Q000150:complications; D005143:Eyelids / Q000601:surgery; D005260:Female; D005355:Fibrosis; D006111:Graves Disease / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000473:pathology / Q000601:surgery; D009916:Orbital Diseases / Q000209:etiology* / Q000628:therapy