Anti-adhesive surfaces through hyaluronan coatings.
The ability to resist adhesion of proteins, bacteria, cells and tissue is an important requirement for the surfaces of medical devices. This article describes a surface-modification process that imparts anti-adhesive properties to the surfaces of biomedical materials through the covalent binding of hyaluronan. It can be applied to a wide range of materials to yield anti-adhesive surfaces on plastics, metals and ceramics.
Pavesio
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Fidia Advanced Biopolymers, Abano Terme, Italy.
Renier
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D
Cassinelli
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C
Morra
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D001422:Bacterial Adhesion; D004864:Equipment and Supplies / Q000592:standards*; D006801:Humans; D006820:Hyaluronic Acid / Q000737:chemistry; D008422:Materials Testing; D013499:Surface Properties; D000267:Tissue Adhesions