title: Strategies for maximizing your chances for weaning success. Limitations--and advantages--of common predictive indices.
abstract: Using indices to predict weaning outcome can avoid premature extubation and unnecessary prolongation of ventilatory support. Unfortunately, none of the indices is consistently able to predict outcome. The key to successful weaning is to assess respiratory function repeatedly with several indices, not just one. The patient should be able to sustain spontaneous breathing for at least 24 hours on minimal partial ventilatory support (a pressure support or a continuous positive airway pressure of 5 cm H2O or a T piece, for example). Indices of maximal inspiratory pressure; work of breathing; and rapid, shallow breathing are useful in evaluating a patient's respiratory muscle performance; airway occlusion pressure is helpful as well when increased neuromuscular drive is a problem.
authors.affiliation: Division of Pulmonary and Critical care Medicine, University of Mississippi Medical Center in Jackson, USA.
authors.forename: R G
authors.initials: RG
authors.lastname: Patel
authors.forename: M F
authors.initials: MF
authors.lastname: Petrini
authors.forename: J R
authors.initials: JR
authors.lastname: Norman
mesh_terms: D005544:Forecasting; D006801:Humans; D012129:Respiratory Function Tests; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D015300:Ventilator Weaning / Q000379:methods*