Mechanisms of optic neuropathy.
Retinal ganglion cell death is the final common pathway of all human optic neuropathies. An understanding of how these cells die, either at the cell body or after axonal injury, may allow development of strategies for rescuing these cells and therefore ameliorating optic nerve disease.
Levin
L A
LA
Department of Ophthalmology and Visual Sciences, University of Wisconsin Medical School, Madison 53792, USA.
D000818:Animals; D001369:Axons / Q000473:pathology; D016923:Cell Death; D006801:Humans; D007511:Ischemia / Q000473:pathology; D009900:Optic Nerve / Q000098:blood supply / Q000473:pathology; D009901:Optic Nerve Diseases / Q000473:pathology*; D012165:Retinal Ganglion Cells / Q000473:pathology