Clinical experience with transvenous implantable cardioverter-defibrillators for treatment of malignant ventricular arrhythmias.
The need for thoracotomy has previously limited the use of the implantable cardioverter-defibrillator. Prior investigators have shown the efficacy and reduced risk of the transvenous implantable cardioverter-defibrillator. In this study, we report our experience with the transvenous implantable cardioverter-defibrillator as a first-line system. Thirty-four patients with mean age 63.2 +/- 10.3 years and mean ejection fraction 32.6 +/- 11.4% underwent implantation of a transvenous cardioverter-defibrillator using an Endotak lead with or without a subcutaneous patch. Twenty-one patients received a biphasic device and the remainder a monophasic device. Thirty-three of 34 patients (97%) were successfully implanted. The mean defibrillation threshold was than < or = 15.3 +/- 3.6J. Overall, 25 of 34 (74%) patients were implanted with a single endocardial lead alone. In the group receiving a biphasic device 19 of 21 (90%) were successfully implanted with a single endocardial lead alone whereas in the group receiving a monophasic device only 6 of 12 (50%) were successfully implanted with single endocardial lead alone (p < 0.05). There were no serious complications. One postoperative death was a result of end-staged congestive heart failure. We conclude that the transvenous implantable cardioverter-defibrillator is safe and efficacious and that incorporation of biphasic waveform may lead to higher rates of implantation of single transvenous lead alone without the need for subcutaneous patch.
Jadonath
R L
RL
Department of Medicine, North Shore University Hospital-Cornell University Medical College, Manhasset, New York 11030, USA.
Pogo
G J
GJ
Goldner
B G
BG
Kalenderian
D
D
Merkatz
K
K
Cohen
M B
MB
Snow
J S
JS
Cohen
T J
TJ
D000328:Adult; D000368:Aged; D017147:Defibrillators, Implantable; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D014693:Ventricular Fibrillation / Q000628:therapy*