Mutagenesis: the power to do harm.
Among the portfolio of tests that may have to be performed on medical devices is the test for mutagenicity. It is far from clear, however, just how significant the risk is of mutagenicity from biomaterials, and how the results of these tests should be interpreted. This article discusses some of the salient features of this difficult subject.
Williams
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Clinical Engineering Department, Royal Liverpool University Hospital, UK. dfw.ce@liverpool.ac.uk
D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects; D004864:Equipment and Supplies / Q000009:adverse effects; D006801:Humans; D016296:Mutagenesis; D009152:Mutagenicity Tests