Psoriasin (S100A7): a putative urinary marker for the follow-up of patients with bladder squamous cell carcinomas.
To search for bladder squamous cell carcinoma markers that are released to the urine a blind and systematic analysis of the protein profiles of fresh tumors, their secreted proteins, as well as the patient's urine was carried out using state-of-the-art proteomic technology. We review the data concerning the putative marker psoriasin (S100A7), which, alone or in combination with other biomarkers, may be valuable for the noninvasive follow-up of patients bearing these tumors.
Ostergaard
M
M
Department of Medical Biochemistry and Danish Centre for Human Genome Research, University of Aarhus, Aarhus C.
Wolf
H
H
Orntoft
T F
TF
Celis
J E
JE
D014408:Biomarkers, Tumor / Q000096:biosynthesis / Q000652:urine*; D002135:Calcium-Binding Proteins / Q000096:biosynthesis / Q000652:urine*; D005500:Follow-Up Studies; D006801:Humans; D018307:Neoplasms, Squamous Cell / Q000652:urine*; D000075023:S100 Calcium Binding Protein A7; D009418:S100 Proteins; D001749:Urinary Bladder Neoplasms / Q000652:urine*
D014408:Biomarkers, Tumor; D002135:Calcium-Binding Proteins; D000075023:S100 Calcium Binding Protein A7; D009418:S100 Proteins; C089242:S100A7 protein, human