[An evaluation of the toxic exposure to inhalation anesthetics and disinfectants on liver function. II].
The object of the study was evaluation of the functional state of the liver of surgeons and anaesthesiologists, exposed to halothane, paradise gas and disinfectants (formaldehyde). A representative group of 107 individuals was involved, distributed into two professional groups: surgeons (AcAT, AIAT, AP, gamma-GT) was determined. The analyses were performed on "Pointe 190", USA. Increased incidence and degree of deviations in the transaminases were established; a correlation between the results from the biochemical analyses and the toxicometric records. In conclusion the established correlations "dose-effect" and "dose-response" confirmed that the liver is a critical organ under the conditions of combined effect exerted by haolthane and paradise gas.
Mikhaĭlova
A
A
Popov
T
T
D000328:Adult; D000368:Aged; D018685:Anesthetics, Inhalation / Q000633:toxicity*; D004796:Clinical Enzyme Tests / Q000706:statistics & numerical data; D004202:Disinfectants / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008505:Medical Staff, Hospital; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects / Q000706:statistics & numerical data; D009873:Operating Rooms; D012307:Risk Factors
D018685:Anesthetics, Inhalation; D004202:Disinfectants