Immunoglobulin variable regions as idiotype vaccines.
This article focuses on the use of immunoglobulin variable regions, including Id, anti-Id, anticlonotypes, and Id engineering as putative vaccines and vaccine strategies for infectious diseases; and specific discussion of Id systems involving antigenic determinants associated with potentially pathogenic organisms.
Hefty
P S
PS
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Kennedy
R C
RC
D000818:Animals; D006801:Humans; D007130:Immunoglobulin Idiotypes / Q000235:genetics / Q000276:immunology*; D007135:Immunoglobulin Variable Region / Q000235:genetics / Q000276:immunology*; D019444:Vaccines, DNA / Q000008:administration & dosage / Q000276:immunology*
D007130:Immunoglobulin Idiotypes; D007135:Immunoglobulin Variable Region; D019444:Vaccines, DNA