Gastroesophageal reflux in children with cystic fibrosis.
The aim of the study is to reveal the frequency of gastroesophageal reflux /GER/ in children with cystic fibrosis /CF/ and the possibilities of GER's management. Twelve children with CF were monitored for GER by 24-hour pH monitoring of the distal part of the oesophagus, according to the instructions of ESPGAN with Digitrapper MK III, at the time of clinical remission of pulmonary involvement. All patients with diagnosed GER were treated with 10 mg. Cisapride an hour after dinner. GER was proven in 7 children older than 6 years, only while asleep and with no correlation with the time of inhalations. Treatment for GER was safe and effective.
Bosheva
M
M
Department of Paediatrics, Higher Medical Institute, Plovdiv, Bulgaria.
Ivancheva
D
D
Genkova
N
N
Lutzkanova
Z
Z
Klinkanova
M
M
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D020117:Cisapride / Q000627:therapeutic use; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male
D005765:Gastrointestinal Agents; D020117:Cisapride