Mapping of secondary somatosensory cortex activation induced by vibrational stimulation: an fMRI study.
Sensory functional MRI was performed in seven normal volunteers at 1. 5 T using a vibratory stimulus applied to the pad of the first finger of the left hand. The data was normalized to a standard atlas, and individual and group statistical parametric maps were computed. Robust bilateral activation was demonstrated in the secondary somatosensory cortex (SII), indicating a bilateral representation of SII in humans. Greater maxima and activation volumes were achieved in contralateral SII as compared to SI. Sensory fMRI can provide a sensitive assay for probing the nature and function of SII in vivo.
Maldjian
J A
JA
Department of Radiology, Ground Floor Founders, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. maldjian@oasis.rad.upenn.edu
Gottschalk
A
A
Patel
R S
RS
Pincus
D
D
Detre
J A
JA
Alsop
D C
DC
D000328:Adult; D000704:Analysis of Variance; D001931:Brain Mapping / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010812:Physical Stimulation; D012016:Reference Values; D013003:Somatosensory Cortex / Q000473:pathology / Q000502:physiology*; D014732:Vibration