[Effects of various concentrations of erythropoietin on cultured erythroblast islands].
Proliferative effects of increasing concentrations of erythropoietin were studied in vitro. The maximal amount of erythroblastic islands consisting of residual macrophages and erythroid cells was observed with the doses 0.5 to 1.5 ME/ml of erythropoietin. Smaller doses stimulated the reconstruction of erythroblastic islands.
Tishevskaia
N V
NV
Medical Academy, Tcheliabinsk, Russia.
Zakharov
Iu M
IuM
Tishevskoĭ
I A
IA
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D046508:Culture Techniques; D004305:Dose-Response Relationship, Drug; D004900:Erythroblasts / Q000187:drug effects* / Q000502:physiology; D004920:Erythropoiesis / Q000187:drug effects* / Q000502:physiology; D004921:Erythropoietin / Q000494:pharmacology*; D051381:Rats
D004921:Erythropoietin