title: Infection rate with replacement of bone fragment in compound depressed skull fractures.
abstract: BACKGROUND
  Traditional management of compound depressed skull fractures entails elevation and removal of all bone fragments with delayed cranioplasty. Bone fragment removal is intended to reduce the potential for infection. However, bone fragment removal often necessitates a second operation to repair the resultant calvarial defect. This study examines the postoperative infection rate when bone fragments are replaced primarily.
  
  
  METHODS
  A retrospective study was carried out of all patients admitted with the diagnosis of compound depressed skull fracture to a university hospital from 1991 to 1996.
  
  
  RESULTS
  Of 52 patients with the diagnosis of compound depressed skull fracture treated at our university hospital over the past 5 years, 32 underwent elevation and repair within 72 hours. All patients except one received antibiotics during surgery and for at least 1.5 days after surgery. Follow-up averaged just over 22 months. In all 32 consecutive patients treated with debridement and elevation of compound depressed skull fractures with primary replacement of bone fragments within 72 hours of injury, there were no infectious sequelae.
  
  
  CONCLUSIONS
  Immediate replacement of bone fragments in compound depressed skull fractures does not increase the risk of infectious complications.
authors: Department of Neurosurgery, Louisiana State University Medical Center, Shreveport 71130-3932, USA.
authors: E L
authors: EL
authors: Wylen
authors: B K
authors: BK
authors: Willis
authors: A
authors: A
authors: Nanda
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D006259:Craniocerebral Trauma / Q000150:complications; D003399:Craniotomy / Q000009:adverse effects* / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012887:Skull Fractures / Q000209:etiology / Q000601:surgery*; D013530:Surgical Wound Infection / Q000209:etiology*; D016896:Treatment Outcome