title: Sequential MRI, SPECT and PET in respiratory syncytial virus encephalitis.
abstract: We report on a 3-year-old girl with respiratory syncytial virus (RSV) encephalitis manifested by disturbance of consciousness, conjugate eye deviation, anuria, truncal ataxia and intention tremor. T2-weighted magnetic resonance imaging (MRI) showed hyperintense areas in the cerebellar cortex. No lesion was detected in the cerebral cortex, pons or spinal cord. The hyperintense areas in the cerebellar cortex diminished with recovery from the clinical manifestations and had resolved 2 months after onset. The MRI lesions in the cerebellum were considered to be due to oedema. SPECT and positron emission tomography (PET), performed 3 months after onset, disclosed areas of hypoperfusion and hypometabolism at the same sites. One year after onset, MRI showed mild atrophy of the cerebellum. Hypoperfusion on SPECT and hypometabolism on PET remained. Neuroimaging showed that ataxia and tremor in this case were the result of cerebellitis. The patient has no neurological deficit except for mild truncal ataxia. This patient is a rare example of RSV encephalitis.
authors: Department of Paediatrics, Izumi Municipal Hospital, 4-10-10 Fuchu-cho, Izumi City, Osaka 594, Japan.
authors: K
authors: K
authors: Hirayama
authors: H
authors: H
authors: Sakazaki
authors: S
authors: S
authors: Murakami
authors: S
authors: S
authors: Yonezawa
authors: K
authors: K
authors: Fujimoto
authors: T
authors: T
authors: Seto
authors: K
authors: K
authors: Tanaka
authors: H
authors: H
authors: Hattori
authors: O
authors: O
authors: Matsuoka
authors: R
authors: R
authors: Murata
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D002675:Child, Preschool; D018792:Encephalitis, Viral / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon