title: Cytogenetic findings in five patients with hairy cell leukemia.
abstract: We studied five cases of hairy cell leukemia (HCL) using conventional cytogenetics. All patients were diagnosed with typical HCL. Chromosome analysis was carried out on a 72-hour culture of peripheral blood. Phytohemagglutinin (PHA) mitogen was used. Clonal chromosome abnormalities were found in 2/5 patients (40%), a complex abnormality being identified in one of them. The chromosomes involved were: 1, 6, 7, 8, and 17. No patient showed trisomy 12 or a 14q+. An interesting result was the finding of del(7)(q32) as a sole anomaly.
authors: Laboratori de Citologia Hematològica, Hospital de l'Esperança, Institut Muncipal d'Investigació Sanitària (IMIM), Barcelona, Spain.
authors: F
authors: F
authors: Solé
authors: S
authors: S
authors: Woessner
authors: L
authors: L
authors: Florensa
authors: B
authors: B
authors: Espinet
authors: E
authors: E
authors: Lloveras
authors: C
authors: C
authors: Pedro
authors: C
authors: C
authors: Besses
authors: J S
authors: JS
authors: Sabrafen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002869:Chromosome Aberrations; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000235:genetics*; D008297:Male; D008875:Middle Aged