title: Subcutaneous nodules caused by Pseudomonas aeruginosa without sepsis.
abstract: Pseudomonas aeruginosa infection can cause a wide array of skin manifestations. While some infections are mild, as are the cases with hot tub folliculitis and toe web or nail infection, others are a result of sepsis and can be fatal without prompt treatment. The classic skin finding of P. aeruginosa sepsis is Ecthyma gangrenosum, but other signs such as papules, petechiae, and hemorrhagic bullae can also be seen. Suppurative panniculitis can also be caused by P. aeruginosa sepsis and clinically manifests as solitary or multiple subcutaneous nodules. Reports in the literature describe these nodules in the setting of clinical sepsis or with positive blood cultures. We report a case of localized subcutaneous nodules on the leg caused by P. aeruginosa in a patient without sepsis or positive blood cultures. The source of the infection was thought to be from a traumatic inoculation. This raises the possibility that P. aeruginosa can cause subcutaneous nodules from a localized infection, perhaps via lymphangitic spread without the manifestations of sepsis.
authors: Department of Dermatology, Medical College of Virginia, Richmond 23298-0164, USA.
authors: C T
authors: CT
authors: Aleman
authors: M L
authors: ML
authors: Wallace
authors: W K
authors: WK
authors: Blaylock
authors: A B
authors: AB
authors: Garrett
mesh_terms: D000368:Aged; D016470:Bacteremia / Q000150:complications; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003937:Diagnosis, Differential; D006801:Humans; D007866:Leg; D008297:Male; D011552:Pseudomonas Infections / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D017192:Skin Diseases, Bacterial / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology