Pulmonary alveolar proteinosis in a patient with chronic myelogenous leukemia.
We describe the case of a 53-year-old Philadelphia-chromosome-positive woman with chronic myelogenous leukemia, who developed pulmonary alveolar proteinosis (PAP). The possible mechanism involved in the pathogenesis of PAP are discussed based on the clinical and laboratory data for this patient as well as on experimental and clinical data reported in the literature.
Tsushima
K
K
Department of Internal Medicine, Nagano Red Cross Hospital, Nagano, Japan.
Koyama
S
S
Saitou
H
H
Takematsu
H
H
Ichiyoshi
T
T
Kubo
K
K
D001774:Blood Chemical Analysis; D018893:Bronchoalveolar Lavage; D001999:Bronchoscopy; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D011649:Pulmonary Alveolar Proteinosis / Q000175:diagnosis / Q000209:etiology*; D012131:Respiratory Insufficiency