Hematologic changes associated with infection.
Hematologic data provide information useful in both the detection of infectious disease and in the monitoring of patients diagnosed with bacterial, viral, fungal, and parasitic infections. Infection, typically accompanied by inflammation, results in changes within the hematopoietic system that can be observed as qualitative and/or quantitative changes in 3 cell lines: Leukocytes, erythrocytes, and thrombocytes. These alterations to hematopoietic cells are mediated via the influence of microbial toxins and cytokines on cellular proliferation, differentiation, and activation.
McKenzie
S B
SB
Department of Clinical Laboratory Sciences, University of Texas Health Science Center, San Antonio 78284-6246, USA. mckenzie@uthscsa.edu
Laudicina
R J
RJ
D001792:Blood Platelets / Q000276:immunology; D016207:Cytokines / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D006402:Hematologic Diseases / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D007239:Infections / Q000150:complications* / Q000276:immunology; D007962:Leukocytes / Q000276:immunology
D016207:Cytokines