title: Administration of toltrazuril during experimental coccidiosis in mule ducks: comparison of the efficacy of a single administration at two different endogenous stages.
abstract: An experimental Eimeria mulardi coccidiosis was reproduced in mule ducks. A single dose of toltrazuril (7 mg per kg) was administered at two different endogenous stages: Day 2 (first meronts) or Day 5 (last meronts and gamonts). The efficacy of the drug was assessed on four criteria (body weight, oocyst counts, macroscopic lesions, and presence of the meronts and gamonts). To have a curative effect, a single dose of toltrazuril should be administered early on. However, a single treatment on Day 5 had a prophylactic effect.
authors: Laboratoire de Parasitologie, Ecole Nationale Vétérinaire de Lyon. 1, Marcy l'Etoile, France.
authors: M C
authors: MC
authors: Reynaud
authors: C M
authors: CM
authors: Chauve
authors: J
authors: J
authors: Gastellu
authors: J M
authors: JM
authors: Gounel
mesh_terms: D000818:Animals; D001835:Body Weight; D002432:Cecum / Q000473:pathology; D003048:Coccidiosis / Q000188:drug therapy / Q000662:veterinary*; D003049:Coccidiostats / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D004372:Ducks / Q000469:parasitology*; D004386:Duodenum / Q000473:pathology; D004539:Eimeria / Q000187:drug effects*; D005243:Feces / Q000469:parasitology; D005260:Female; D007082:Ileum / Q000473:pathology; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000662:veterinary*; D007583:Jejunum / Q000473:pathology; D010270:Parasite Egg Count / Q000662:veterinary; D011201:Poultry Diseases / Q000188:drug therapy* / Q000469:parasitology; D012007:Rectum / Q000473:pathology; D014227:Triazines / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D003049:Coccidiostats; D014227:Triazines; C036670:toltrazuril