title: The effect of neodymium: YAG capsulotomy on contrast sensitivity and the evaluation of methods for its assessment.
abstract: OBJECTIVE
  To determine the most appropriate method for measuring the effect on contrast sensitivity of neodymium:YAG (Nd:YAG) posterior capsulotomy for early posterior capsular opacification (PCO).
  
  
  METHODS
  Prospective comparison of five different methods for luminous contrast sensitivity testing in patients undergoing capsulotomy.
  
  
  METHODS
  Sixteen patients with PCO involving the visual axis and visual acuities of 20/40 or better were recruited sequentially.
  
  
  METHODS
  All patients were tested with each of the five tests before and after Nd:YAG capsulotomy.
  
  
  METHODS
  The contrast sensitivity function was measured with variable contrast sine wave gratings using the Vistech VCTS 6500, Mentor B-VAT-II and a computer graphics system. Peak contrast sensitivity at 3 cyc/deg was compared with two letter tests, the Pelli-Robson chart, and a computer that generated optotypes.
  
  
  RESULTS
  Significant generalized improvement that was not frequency selective was measured over the entire contrast sensitivity function after capsulotomy. The five tests did not significantly differ (P > 0.05) in their measurement of peak contrast sensitivity (3 cyc/deg) improvement after capsulotomy. Letter-based tests showed better agreement and lower variance than gratings tests. Visual acuity and contrast sensitivity improvement were poorly correlated.
  
  
  CONCLUSIONS
  This study shows that contrast sensitivity is adequately documented by a single measurement at 3 cyc/deg, is an informative supplement to visual acuity, and that little extra information is to be gained by measuring further spatial frequencies in eyes with PCO. Peak contrast sensitivity is best determined using a letter-based test.
authors: Department of Ophthalmology, St. Thomas' Hospital, London, England, UK.
authors: J C
authors: JC
authors: Tan
authors: D J
authors: DJ
authors: Spalton
authors: G B
authors: GB
authors: Arden
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000209:etiology / Q000473:pathology; D002387:Cataract Extraction / Q000009:adverse effects; D015350:Contrast Sensitivity; D006801:Humans; D053685:Laser Therapy; D007903:Lens Capsule, Crystalline / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D011446:Prospective Studies; D014787:Vision Tests / Q000379:methods*; D014792:Visual Acuity