title: Rheodynamic model of cardiac pressure pulsations.
abstract: To analyse parametrically (in terms of the qualitative theory of dynamical systems) the mechanical influence of inertia, resistance (positive and negative), elasticity and other global properties of the heart-muscle on the left ventricular pressure, an active rheodynamic model based on the Newtons's principles is proposed. The equation of motion of the heart mass centre is derived from an energy conservation law balancing the rate of mechanical (kinetic and potential) energy variation and the power of chemical energy influx and dissipative energy outflux. A corresponding dynamical system of two ordinary differential equations is obtained and parametrically analysed in physiological conditions. As a result, the following main conclusion is made: in physiological norm, because of the heart electrical activity, its equilibrium state is unstable and around it, mechanical self-oscillations emerge. In case the electrical activity ceases, an inverse phase reconstruction occurs during which the unstable equilibrium state of the system becomes stable and the self-oscillations disappear.
authors: Institute of Mechanics and Biomechanics, Sofia, Bulgaria. vgp@bgcict.acad.bg
authors: V G
authors: VG
authors: Petrov
authors: S G
authors: SG
authors: Nikolov
mesh_terms: D002302:Cardiac Output / Q000502:physiology; D006801:Humans; D008955:Models, Cardiovascular; D009200:Myocardial Contraction / Q000502:physiology; D009716:Numerical Analysis, Computer-Assisted; D012212:Rheology; D016277:Ventricular Function, Left / Q000502:physiology*