title: Peribulbar anaesthesia: a double-blind comparison of three local anaesthetic solutions.
abstract: A prospective, randomised, double-blinded study comparing three agents for peribulbar anaesthesia is reported. Sixty patients undergoing extracapsular cataract extraction under local anaesthesia were randomly allocated to receive peribulbar anaesthesia with lignocaine 2% with adrenaline; prilocaine 3% with felypressin 0.03 IU.ml-1 or 2% lignocaine and 0.5% bupivacaine in a ratio of 1:1, using a standardised two-injection technique. The pain of injection, time of onset of the block and the operating conditions at the start and finish of surgery were assessed. Peribulbar anaesthesia using lignocaine 2% was significantly more painful than the other solutions. The onset of anaesthesia adequate for surgery was similar in all three groups. Prilocaine 3% with felypressin was associated with the greatest number of blocks providing total akinesia of the eye. Inadequate duration of anaesthesia was seen in only one case; the solution used for this block was 2% lignocaine.
authors: Department of Anaesthetics, Royal Group of Hospitals Trust, Belfast, UK.
authors: A
authors: A
authors: Bedi
authors: U
authors: U
authors: Carabine
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000556:Ambulatory Surgical Procedures; D000772:Anesthesia, Local / Q000379:methods*; D000779:Anesthetics, Local; D002045:Bupivacaine; D002387:Cataract Extraction; D004311:Double-Blind Method; D004837:Epinephrine; D005259:Felypressin; D005260:Female; D006490:Hemostatics; D006801:Humans; D008012:Lidocaine; D008297:Male; D008875:Middle Aged; D011318:Prilocaine; D011446:Prospective Studies
chemical_list: D000779:Anesthetics, Local; D006490:Hemostatics; D011318:Prilocaine; D005259:Felypressin; D008012:Lidocaine; D002045:Bupivacaine; D004837:Epinephrine