Bioactivity studies of Salvia transsylvanica (Schur ex Griseb) grown in Egypt.
Some pharmacological effects of the ethanol extract of Salvia transsylvanica (Schur ex Griseb) were experimentally investigated. The tested extract of the plant proved to be relatively nontoxic (LD50 = 4.437 g/kg b.wt.). The extract induced significant analgesic, antipyretic, antiepileptic, antiinflammatory, antiulcerogenic, as well as tranquillizing activities, besides increasing the bleeding time and exhibiting no central skeletal muscle relaxant effect compared with control groups and standard drugs.
Maklad
Y A
YA
Pharmaceutical Sciences, Department, National Research Centre, Cairo, Egypt.
Aboutabl
E A
EA
el-Sherei
M M
MM
Meselhy
K M
KM
D000700:Analgesics / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology* / Q000627:therapeutic use; D000927:Anticonvulsants / Q000494:pharmacology* / Q000627:therapeutic use; D001760:Bleeding Time; D004487:Edema / Q000517:prevention & control; D004534:Egypt; D019686:Lamiaceae / Q000737:chemistry / Q000627:therapeutic use; D008297:Male; D051379:Mice; D010437:Peptic Ulcer / Q000517:prevention & control; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D051381:Rats; D012640:Seizures / Q000517:prevention & control
D000700:Analgesics; D000893:Anti-Inflammatory Agents; D000927:Anticonvulsants; D010936:Plant Extracts