[Impact of ozonized sorbent hemocarboperfusion on kallikrein-kinin system in patients with progressive pulmonary tuberculosis].
The impact of ozonized sorbent hemocarboperfusion on the kallicrein-kinin system (KKS) was studied in 21 patients with slowly progressive (Group 1) and acute (Group 2) pulmonary tuberculosis. In Group 1 patients, the baseline values of KKS were suggestive of its depression with an increase in alpha 1-protease inhibitor (alpha 1-PI). In Group 2 patients, the activity of kallikrein was twice higher than the mean normal values with increased uptake of its precursor, a dramatic decrease in the level of alpha 2-macroglobulin and an acute phasic elevation of alpha 1-PI.
Belianin
I I
II
Kaminskaia
G O
GO
D015415:Biomarkers / Q000097:blood; D018450:Disease Progression; D005500:Follow-Up Studies; D006464:Hemoperfusion / Q000379:methods; D006801:Humans; D016234:Kallikrein-Kinin System / Q000187:drug effects*; D010083:Oxidants, Photochemical / Q000494:pharmacology*; D010126:Ozone / Q000494:pharmacology*; D011480:Protease Inhibitors / Q000097:blood; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000097:blood* / Q000628:therapy; D000511:alpha-Macroglobulins / Q000378:metabolism
D015415:Biomarkers; D010083:Oxidants, Photochemical; D011480:Protease Inhibitors; D000511:alpha-Macroglobulins; D010126:Ozone