title: Treatment for accidental occlusion of the hepatic artery after hepatic resection: report of two cases.
abstract: Two patients in whom accidental hepatic artery occlusion (HAO) occurred after hepatic resection (Hx) were reported. A 59-year-old female who underwent Hx for hepatocellular carcinoma with underlying liver cirrhosis developed HAO on postoperative day (POD) 14 and died of hepatic failure on POD 23. The autopsy findings showed multiple necrosis in the remnant liver and an extraluminal hematoma of the hepatic artery, suggesting an injury caused by Pringle's maneuver. The second case was a 53-year-old male who underwent Hx for cholangiocarcinoma without any underlying liver disease. He developed HAO on POD 6, and radiological studies indicated a pseudoaneurysma formation and severe stenosis of the hepatic artery. It was speculated that the cause of the HAO was intraluminal injury of the hepatic artery during an angiographic study conducted prior to Hx. Partial arterialization of the portal vein was performed, following which his liver function test results improved. In both cases, measuring the serum hepatocyte growth factor level and the hepatic vein oxygen saturation proved useful, not only for determining the degree of liver injury, but also for predicting the outcome after treatments for HAO. Furthermore, the partial arterialization of the portal vein for HAO after Hx may rescue the normal remnant liver.
authors: First Department of Surgery, Kagoshima University, School of Medicine, Japan.
authors: G
authors: G
authors: Tanabe
authors: K
authors: K
authors: Kawaida
authors: M
authors: M
authors: Hamanoue
authors: K
authors: K
authors: Kihara
authors: S
authors: S
authors: Hirata
authors: M
authors: M
authors: Maemura
authors: S
authors: S
authors: Ueno
authors: T
authors: T
authors: Aikou
mesh_terms: D017541:Aneurysm, False / Q000209:etiology; D001650:Bile Duct Neoplasms / Q000601:surgery; D001653:Bile Ducts, Intrahepatic; D006528:Carcinoma, Hepatocellular / Q000601:surgery; D018281:Cholangiocarcinoma / Q000601:surgery; D003251:Constriction, Pathologic; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects*; D006499:Hepatic Artery / Q000000981:diagnostic imaging / Q000293:injuries / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011859:Radiography