title: Translocation (2;3)(p21;q26) as the sole anomaly in a case of primary myelofibrosis.
abstract: Translocation t(2p;3q) is a rare but recurrent finding in myeloid disorders. We present the first case of primary myelofibrosis with t(2;3)(p21;q26) as the sole chromosomal anomaly. The comparison with the 11 other previously published myeloid-associated t(2p;3q) cases confirms that this nonrandom translocation involves a pluripotent stem cell and is associated with a poor prognosis.
authors: Department of Human Genetics, University of Liège, Belgium.
authors: C
authors: C
authors: Herens
authors: J P
authors: JP
authors: Hermanne
authors: F
authors: F
authors: Tassin
authors: M F
authors: MF
authors: Fassotte
authors: A
authors: A
authors: Thiry
authors: M
authors: M
authors: Jamar
authors: N
authors: N
authors: Schaaf-Lafontaine
authors: G
authors: G
authors: Fillet
authors: L
authors: L
authors: Koulischer
mesh_terms: D000368:Aged; D002889:Chromosomes, Human, Pair 2; D002893:Chromosomes, Human, Pair 3; D006801:Humans; D008297:Male; D055728:Primary Myelofibrosis / Q000235:genetics*; D014178:Translocation, Genetic