title: No evidence of hepatitis G virus in fulminant hepatic failure in children.
abstract: BACKGROUND
  The cause of fulminant hepatic failure in children remains unknown, but a viral origin has been suspected in most cases. The recently discovered blood-borne virus, hepatitis G, has been suggested as a possible causative agent.
  
  
  METHODS
  Six consecutive children who underwent liver transplantation for fulminant hepatic failure were studied. The children were tested for hepatitis G virus antibodies and hepatitis G virus RNA by polymerase chain reaction after excluding other causes of fulminant hepatic failure.
  
  
  RESULTS
  No evidence of hepatitis G virus infection was found in these patients.
  
  
  CONCLUSIONS
  Hepatitis G virus is unlikely to be a common cause of fulminant hepatic failure in pediatric patients from the upper midwestern United States.
authors: Department of Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.
authors: R G
authors: RG
authors: Perez
authors: N N
authors: NN
authors: Zein
authors: D K
authors: DK
authors: Freese
authors: J J
authors: JJ
authors: Perrault
authors: J L
authors: JL
authors: Steers
authors: H L
authors: HL
authors: Sharp
authors: D H
authors: DH
authors: Persing
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D018067:Flaviviridae / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D006501:Hepatic Encephalopathy / Q000601:surgery / Q000821:virology*; D006508:Hepatitis Antibodies / Q000097:blood; D006801:Humans; D007223:Infant; D016031:Liver Transplantation; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000097:blood
chemical_list: D006508:Hepatitis Antibodies; D012367:RNA, Viral