title: An investigation of factors contributing to styrene and styrene-7,8-oxide exposures in the reinforced-plastics industry.
abstract: During the manufacturing of reinforced plastics, large amounts of styrene and trace quantities of styrene-7,8-oxide (SO) are released. Since previous work suggests that inhalation of even small amounts of SO might be an important health risk, we investigated several possible factors contributing to styrene and SO exposure during the manufacture of reinforced plastics. Factors related to job type, worker and the type and quantity of styrene-containing resins were investigated using mixed-effects multiple linear regression models. Overall, SO exposure levels were positively correlated with styrene exposure levels. However, this correlation was statistically significant only among hand laminators who had the highest exposures to both styrene and SO. An important factor for predicting both styrene and SO concentrations was the type of resin used, while the quantity of resin consumed was predictive of styrene but not of SO exposure. Since So exposure appears to be associated with factors other than coexposure to styrene, more effort should be placed on investigating emissions of SO per se. The type of mixed-models regression analysis employed in this study can be used for clarifying the underlying patterns for exposures to styrene and SO as well as for evaluating preventive measures.
authors: Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill 27599-7400, USA. leena__french@unc.edu
authors: L A
authors: LA
authors: Nylander-French
authors: L L
authors: LL
authors: Kupper
authors: S M
authors: SM
authors: Rappaport
mesh_terms: D002273:Carcinogens / Q000032:analysis*; D004784:Environmental Monitoring / Q000379:methods; D004852:Epoxy Compounds / Q000032:analysis*; D005387:Finland; D006801:Humans; D007221:Industry; D016014:Linear Models; D009153:Mutagens / Q000032:analysis*; D016273:Occupational Exposure / Q000032:analysis*; D009790:Occupations; D010969:Plastics; D012116:Resins, Plant / Q000737:chemistry; D012307:Risk Factors; D020058:Styrene / Q000032:analysis*
chemical_list: D002273:Carcinogens; D004852:Epoxy Compounds; D009153:Mutagens; D010969:Plastics; D012116:Resins, Plant; D020058:Styrene; C013690:styrene oxide