title: [Stent restenosis: therapy concepts and possibilities for prevention].
abstract: BACKGROUND
  In-stent restenosis has become a significant problem for interventional cardiologists. Due to different pathogenic causes it remains unclear whether a uniform therapeutic regimen is appropriate.
  
  
  METHODS
  Redilatation has predominantly been used for the treatment of instent restenosis, however, in long and diffuse restenotic stents, long-term results are reported to be poor. Therefore, tissue-debulking techniques may have beneficial effects in complex cases of in-stent restenosis. The therapeutic benefit of intracoronary radiation, local drug delivery or gene transfer has not been evaluated so far.
  
  
  CONCLUSIONS
  Therefore, prevention of the iatrogenic entity in-stent restenosis has become more important.
authors: Medizinische Klinik I, Universitätsklinikum der RWTH Aachen. prad@pcserver.mk1.rwth-aachen.de
authors: P W
authors: PW
authors: Radke
authors: J
authors: J
authors: vom Dahl
authors: H G
authors: HG
authors: Klues
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation*; D003327:Coronary Disease / Q000628:therapy*; D006083:Graft Occlusion, Vascular / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*; D006801:Humans; D012008:Recurrence; D019233:Retreatment; D012307:Risk Factors; D015607:Stents; D016896:Treatment Outcome