[Impact of disorders in blood rheology on progress of glaucoma in patients with stable normalized intraocular pressure].
Comparative study of blood rheology in 53 patients (76 eyes) without stabilization of primary glaucoma with normalized intraocular pressure (group 1) and in 43 patients (61 eyes) with stabilized course (group 2) showed significant differences between the two groups. In group 1 erythrocyte aggregation was increased in 79.3% and their deformability decreased in 88.7%; high content of Willebrandt's factor was detected in 83% patients. By contrast, in group 2 these shifts were detected in only 20.9 and 23.3% patients, respectively, while the content of Willebrandt's factor was normal. The detected rheological shifts were in high correlation with an unstable course of glaucoma, and their severity may serve as a prognostic sign for predicting the course of glaucoma in patients with normalized intraocular pressure.
Egorov
V V
VV
Bachaldin
I L
IL
Sorokin
E L
EL
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D018450:Disease Progression; D004903:Erythrocyte Aggregation; D004907:Erythrocyte Deformability; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000097:blood / Q000209:etiology / Q000503:physiopathology*; D006402:Hematologic Diseases / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D018056:Hemorheology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D011379:Prognosis