Fluorescent probes for living cells.
The functional characteristics of fluorescent probes used for imaging and measuring dynamic processes in living cells are reviewed. Initial consideration is given to general design requirements for delivery, targeting, detectability and fluorescence readout, and current technologies for attaining them. Discussion then proceeds to the more application-specific properties of intracellular ion indicators, membrane potential sensors, probes for proteins and lipids, and cell viability markers.
Johnson
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Molecular Probes, Eugene, OR 97402-9165, USA.
D000818:Animals; D002468:Cell Physiological Phenomena; D003584:Cytological Techniques; D003593:Cytoplasm / Q000378:metabolism; D015195:Drug Design; D005452:Fluoresceins / Q000737:chemistry / Q000378:metabolism; D005456:Fluorescent Dyes / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D013329:Structure-Activity Relationship
D005452:Fluoresceins; D005456:Fluorescent Dyes