title: Evolution and factors associated with biological-risk accidents reported in a university hospital in Spain, 1989 to 1995.
abstract: BACKGROUND
  The objective of this study was to describe the profile and evolution of accidents involving risk of transmission of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) reported in a large Spanish hospital, together with the preventive measures administered and the factors associated with high-risk accidents.
  
  
  METHODS
  Data used were the accidents recorded in the hospital during the period from January 1989 to December 1995. A logistic model, using age, gender, service, occupation, and year of accident as independent variables was constructed to study the factors associated with these accidents.
  
  
  RESULTS
  The study included 1,009 accidents. Accidents were more common among nurses, female doctors, younger workers, and persons who worked in surgical settings. Of the total sources of infection studied, 11.6% were positive for HBV, 28.2% for HCV, and 24.4% for HIV. No seroconversions were detected in the partial follow-ups conducted. The factors associated with high-risk accidents were gender (relative risk [RR], 2.01; 95% confidence interval [CI95], 1.24-3.60); occupation as physician (RR, 2.57; CI95, 1.54-4.29) or as nursing staff (RR, 1.80; CI95, 1.12-2.89); and working in a surgical service (RR, 2.01; CI95, 1.27-3.18). Younger workers had more accidents overall, but older workers were more likely to have high-risk exposure. In the multivariate analysis, the occupation (physician and nursing staff) was the most important variable when adjusted by the other factors.
  
  
  CONCLUSIONS
  Our results suggest that a greater effort still is required in the application and evaluation of preventive measures. New safety systems, with clearly proven cost-effectiveness, should be developed and applied.
authors: Servicio Medicina Preventiva y Salud Pública, Hospital Universitario "Puerta del Mar," Cádiz, Spain.
authors: I
authors: I
authors: Failde
authors: F J
authors: FJ
authors: López
authors: J A
authors: JA
authors: Córdoba
authors: M
authors: M
authors: Zarzuela
authors: E
authors: E
authors: Benítez
authors: V
authors: V
authors: Senabre
mesh_terms: D000328:Adult; D003428:Cross Infection / Q000453:epidemiology*; D003625:Data Collection; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000635:transmission*; D006509:Hepatitis B / Q000453:epidemiology / Q000635:transmission*; D006526:Hepatitis C / Q000453:epidemiology / Q000635:transmission*; D006746:Hospital Bed Capacity, 500 and over; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional; D008137:Longitudinal Studies; D008297:Male; D016273:Occupational Exposure; D010564:Personnel, Hospital / Q000706:statistics & numerical data*; D013030:Spain / Q000453:epidemiology