Neural development: The semantics of axon guidance.
Recent studies of the semaphorin family of axon guidance signals and their receptors have revealed a surprising versatility in the ways that they can be used solve problems in neural development, and provided new opportunities for understanding how guidance information is interpreted beneath the cell surface.
Van Vactor
D V
DV
Department of Cell Biology, Program in Neuroscience, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA. Davie@hms.harvard.edu
Lorenz
L J
LJ
D000818:Animals; D001369:Axons / Q000502:physiology*; D015816:Cell Adhesion Molecules, Neuronal / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000196:embryology / Q000378:metabolism; D005314:Embryonic and Fetal Development; D006110:Grasshoppers / Q000196:embryology / Q000378:metabolism; D006801:Humans; D019476:Insect Proteins / Q000502:physiology; D008565:Membrane Proteins / Q000502:physiology; D051379:Mice; D008959:Models, Neurological; D009024:Morphogenesis; D005810:Multigene Family; D009419:Nerve Tissue Proteins / Q000502:physiology; D009420:Nervous System / Q000166:cytology / Q000196:embryology; D039942:Neuropilin-1; D011956:Receptors, Cell Surface / Q000502:physiology; D011993:Recombinant Fusion Proteins / Q000502:physiology; D039961:Semaphorins; D015398:Signal Transduction
D015816:Cell Adhesion Molecules, Neuronal; D029721:Drosophila Proteins; D019476:Insect Proteins; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; C492116:PLXNA1 protein, human; C492114:Plxna1 protein, mouse; C492113:Plxna2 protein, mouse; C492112:Plxna3 protein, mouse; C492110:Plxna4 protein, mouse; D011956:Receptors, Cell Surface; D011993:Recombinant Fusion Proteins; C103150:Sema4d protein, mouse; D039961:Semaphorins; C116483:plexA protein, Drosophila; D039942:Neuropilin-1