title: Evaluation of the Vega haematology analyser in a university hospital setting.
abstract: The performance of the ABX Vega haematology analyser was compared with that of the Sysmex NE-8000, with specific attention to flagging performance and ergonomics. Eight hundred routine samples underwent precision and interinstrument variability studies and 168 samples corresponding to various blood disorders were studied meanwhile. Results from the two instruments gave excellent correlation (r > 0.900) for most parameters except MCHC (r = 0.114), basophil and monocyte percentages (r = 0.617 and 0.552, respectively). The reproducibility, repeatability, linearity, carry-over and stability of the Vega were satisfactory; 'flagging' occurred in 31% of routine samples with sensitivity 88.8%, specificity 41.3% and positive predictive value 85.7%. Various flags appeared in 91% (42/46) of cases where blast cells were microscopically identified. In the four remaining cases, CBC anomalies would themselves have justified microscopic examination of a smear. On 'CBC only' mode reagent consumption was significantly reduced. In the laboratory the analyser was best appreciated for its user-friendliness.
authors: Laboratoire d'Hématologie, Hôpital Rangueil, CHU Toulouse, France.
authors: J X
authors: JX
authors: Corberand
authors: C
authors: C
authors: Segonds
authors: A M
authors: AM
authors: Fontanilles
authors: J P
authors: JP
authors: Cambus
authors: G
authors: G
authors: Fillola
authors: P
authors: P
authors: Laharrague
mesh_terms: D001322:Autoanalysis / Q000295:instrumentation*; D001772:Blood Cell Count / Q000191:economics / Q000295:instrumentation*; D006804:Ergonomics; D005069:Evaluation Studies as Topic; D005188:False Negative Reactions; D006784:Hospitals, Teaching; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D007755:Laboratories, Hospital; D007958:Leukocyte Count / Q000295:instrumentation; D012015:Reference Standards; D015203:Reproducibility of Results