[Extrinsic allergic alveolitis].
Extrinsic allergic alveolitis (EEA) is a lung disease mediated by immunologic mechanisms and induced by repeated exposure to organic dusts. EAA in children are mostly observed around 10 years of age. Subacute clinical presentation is the most frequent. Diagnosis is based on simultaneous presence of most of the following arguments: exposure to a known risk factor, spontaneous improvement after cessation of the exposure, identification of specific precipitins, demonstrative aspects on X-ray and tomodensitometry, and CD8+ lymphocytosis in bronchoalveolar lavage. Lung biopsy and specific provocation test are rarely necessary for diagnosis. Treatment is based on total eviction from inhaled antigen and on oral corticosteroids in acute and subacute forms.
Delacourt
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Service de pneumologie et de pathologie professionnelle, centre hospitalier intercommunal de Créteil, France.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000542:Alveolitis, Extrinsic Allergic / Q000175:diagnosis / Q000628:therapy; D001992:Bronchoalveolar Lavage Fluid; D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed
D000305:Adrenal Cortex Hormones