title: Do laryngeal mask airway devices attenuate liquid flow between the esophagus and pharynx? A randomized, controlled cadaver study.
abstract: In this randomized, controlled cadaver study, we tested the hypothesis that the standard laryngeal mask airway (LMA) and flexible laryngeal mask airway (FLMA) attenuate liquid flow between the esophagus and pharynx. Fifty fresh cadavers were studied in four LMA groups. Ten female cadavers had a size 4 LMA and 10 had a size 4 FLMA; 10 male cadavers had a size 5 LMA and 10 had a size 5 FLMA; 5 male and 5 female cadavers functioned as controls. The chest was opened, and the infusion set of a pressure-controlled, continuous flow pump was inserted into the esophagus and ligated into place. Esophageal pressure was increased in 2-cm H2O increments. Regurgitation pressure was the esophageal pressure at which fluid was first seen with a fiberoptic scope in the hypopharynx (control group) and above the cuff or within the bowl (LMA groups). This was performed in the LMA groups at 0-40 mL cuff volume in 10-mL increments. Mean (95% confidence interval) regurgitation pressure for the control group was 7 (6-8) cm H2O and for the LMA groups combined was 19 (17-20) cm H2O at 0 mL cuff volume, 47 (41-52) cm H2O at 10 mL, 51 (44-55) cm H2O at 20 mL, 52 (45-56) cm H2O at 30 mL, and 52 (45-55) cm H2O at 40 mL. The increase in regurgitation pressure with increasing cuff volume from 0 to 10 mL was statistically significant (P < 0.0001). Regurgitation pressure was higher for the LMA groups at all cuff volumes compared with the control group (P < 0.0001). There were no differences in regurgitation pressure among the LMA groups. We conclude that the correctly placed LMA and FLMA attenuate liquid flow between the esophagus and pharynx.
  
  
  CONCLUSIONS
  We have shown, in cadavers, that the correctly placed standard and flexible laryngeal mask airways attenuate liquid flow between the pharynx and esophagus.
authors: Department of Anaesthesia and Intensive Care Medicine, Leopold-Franzens University, Innsbruck, Austria.
authors: C
authors: C
authors: Keller
authors: J
authors: J
authors: Brimacombe
authors: C
authors: C
authors: Rädler
authors: F
authors: F
authors: Pühringer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002102:Cadaver; D004947:Esophagus / Q000503:physiopathology*; D005260:Female; D005336:Fiber Optic Technology; D006801:Humans; D017214:Laryngeal Masks / Q000009:adverse effects* / Q000592:standards; D008297:Male; D010614:Pharynx / Q000503:physiopathology*; D011312:Pressure