title: Design and analysis of research on sport performance enhancement.
abstract: OBJECTIVE
  The purpose of this study was to assess research aimed at measuring performance enhancements that affect success of individual elite athletes in competitive events.
  
  
  METHODS
  Simulations show that the smallest worthwhile enhancement of performance for an athlete in an international event is 0.7-0.4 of the typical within-athlete random variation in performance between events. Using change in performance in events as the outcome measure in a crossover study, researchers could delimit such enhancements with a sample of 16-65 athletes, or with 65-260 in a fully controlled study. Sample size for a study using a valid laboratory or field test is proportional to the square of the within-athlete variation in performance in the test relative to the event; estimates of these variations are therefore crucial and should be determined by repeated-measures analysis of data from reliability studies for the test and event. Enhancements in test and event may differ when factors that affect performance differ between test and event; overall effects of these factors can be determined with a validity study that combines reliability data for test and event. A test should be used only if it is valid, more reliable than the event, allows estimation of performance enhancement in the event, and if the subjects replicate their usual training and dietary practices for the study; otherwise the event itself provides the only dependable estimate of performance enhancement. Publication of enhancement as a percent change with confidence limits along with an analysis for individual differences will make the study more applicable to athletes. Outcomes can be generalized only to athletes with abilities and practices represented in the study.
  
  
  CONCLUSIONS
  estimates of enhancement of performance in laboratory or field tests in most previous studies may not apply to elite athletes in competitive events.
authors: Department of Physiology and School of Physical Education, University of Otago, Dunedin, New Zealand. will.hopkins@otago.ac.nz
authors: W G
authors: WG
authors: Hopkins
authors: J A
authors: JA
authors: Hawley
authors: L M
authors: LM
authors: Burke
mesh_terms: D006801:Humans; D017063:Outcome Assessment, Health Care; D010919:Placebos; D015203:Reproducibility of Results; D012107:Research Design; D013177:Sports; D013647:Task Performance and Analysis
chemical_list: D010919:Placebos