title: Breast cancer and barrier contraception: postulated and corroborated potential for prevention.
abstract: A case-control study and a number of ecological surveys have been conducted in order to test the hypothesis that a reduced exposure to human semen factors during the reproductive lives is an etiological risk factor in the development of breast cancer in married women. The results of the retrospective study, carried out jointly at two universities in the USA during 1974-1978, corroborate the postulated association between the use of barrier contraception (condom or withdrawal) and the breast cancer development in women. The sequential surveys of the last 20 years provided ecological evidence of the predicted and anticipated natural experiment, the epidemic rise of breast cancer internationally during the decades of 1980s and 1990s, and further corroborated the potential for a primary (non-chemical) prevention of breast cancer in the community.
authors: MEDICS Group, Skopje, Republic of Macedonia.
authors: A N
authors: AN
authors: Gjorgov
mesh_terms: D001943:Breast Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D003076:Coitus Interruptus; D017280:Condoms; D003267:Contraception / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008954:Models, Biological; D012189:Retrospective Studies; D012661:Semen; D014481:United States / Q000453:epidemiology