title: [Case of cardiac amyloidosis associated with IgG-K multiple myeloma in the framework of restrictive myocardiopathy].
abstract: Primary amyloidosis, due to amassing of fragments of light chains of IgG, often causes cardiac involvement. We describe a 65-year-old woman with multiple myeloma efficaciously treated with chemotherapy. Amyloidosis had been supported by myelic biopsy. The patient came to our observation because of right heart failure, hypotension and syncope: she was treated with a dopamine i.v. and was in cachectic status. She had a moderate pericardial effusion. ECG showed reduction of QRS amplitude, I degree atrioventricular block, posterior fascicular and right bundle branch block. Right cardiac catheterization showed a restrictive situation. After 1 week exitus occurred by asystole. In this case, there were other involvements by amyloidosis, besides the cardia one: that of autonomic nervous system and, probably, surrenal.
authors: UO di Malattie Cardiovascolari, Azienda USL 8, Area a Gestione Sperimentale Valdarno, S Giovanni Valdarno, AR.
authors: S
authors: S
authors: Baldassarre
authors: G
authors: G
authors: Falsini
authors: S
authors: S
authors: Amidei
authors: M
authors: M
authors: Romei
authors: M
authors: M
authors: Forzoni
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000473:pathology; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D002313:Cardiomyopathy, Restrictive / Q000150:complications* / Q000175:diagnosis; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D009101:Multiple Myeloma / Q000150:complications* / Q000276:immunology
chemical_list: D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains