title: Influence of stimulation of the olivocerebellar pathway by harmaline on spatial learning in the rat.
abstract: Administration of harmaline to the rat, which activates synchronously and rhythmically the olivary neurons and the olivocerebellar pathway, elicits visuo-motor, spatial learning and spatial memory deficiencies which are dose-dependent. Since activation and lesion of the olivocerebellar pathway have similar effects, it is concluded that normal functioning of this pathway is required for spatial learning achievement.
authors: UPRES PSY.CO 1780, Faculté des Sciences, Laboratoire de Neurobiologie de l'Apprentissage, Université de Rouen, 76821 Mont-Saint-Aignan Cedex, France.
authors: C
authors: C
authors: Meignin
authors: P
authors: P
authors: Hilber
authors: J
authors: J
authors: Caston
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D002531:Cerebellum / Q000187:drug effects*; D003463:Cues; D006246:Harmaline / Q000494:pharmacology*; D008297:Male; D018782:Maze Learning / Q000187:drug effects*; D008568:Memory / Q000187:drug effects*; D011939:Mental Recall / Q000187:drug effects; D009434:Neural Pathways / Q000187:drug effects; D009474:Neurons / Q000187:drug effects; D009847:Olivary Nucleus / Q000166:cytology / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013268:Stimulation, Chemical
chemical_list: D006246:Harmaline