Co-incidental presentation of IgA lambda multiple myeloma and pleural involvement with IgM kappa non-Hodgkin's lymphoma.
Pleural effusions occur in approximately 6% of patients with myeloma. The aetiology is multifactorial and effusions due to pleural myelomatous involvement are rare, occurring in < 1% of cases. We report the case of a 68-year-old lady who presented with IgA myeloma and a concurrent pleural effusion due to a second IgM kappa producing B cell neoplasm. The former responded but the latter was resistant to standard myeloma therapy.
Manley
R
R
Department of Haematology, Christchurch Hospital, New Zealand.
Monteath
J
J
Patton
W N
WN
D000368:Aged; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood; D007145:Immunoglobulin kappa-Chains / Q000097:blood*; D007146:Immunoglobulin lambda-Chains / Q000097:blood*; D008228:Lymphoma, Non-Hodgkin / Q000097:blood* / Q000150:complications* / Q000276:immunology; D009101:Multiple Myeloma / Q000150:complications*; D010996:Pleural Effusion / Q000150:complications* / Q000276:immunology
D007070:Immunoglobulin A; D007075:Immunoglobulin M; D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains