title: Effects of anxiety sensitivity on anxiety and pain during a cold pressor challenge in patients with panic disorder.
abstract: Fear of anxiety symptoms, or anxiety sensitivity (AS), has been extensively studied in anxiety disorders and more recently has been linked to other psychopathological conditions including pain. Asmundson and colleagues have suggested that AS may act as a risk factor for chronic pain and several studies have demonstrated an association between AS, avoidance behaviors and pain. The present study assessed whether AS levels would be predictive of pain and anxiety during a brief pain induction task. Clinical participants meeting DSM-IV criteria for panic disorder (n = 22) were age and sex matched with nonclinical controls (n = 22) and exposed to a 2-min cold pressor challenge. Diagnostic status and AS were significantly predictive of pain and anxiety during the cold pressor task. Moreover, AS appears to mediate the relationship between diagnostic status and pain. However, AS appears to be only indirectly associated with pain through its contribution to anxiety.
authors: Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4799, USA. schmidt.283@osu.edu
authors: N B
authors: NB
authors: Schmidt
authors: J H
authors: JH
authors: Cook
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001007:Anxiety / Q000503:physiopathology / Q000523:psychology*; D016022:Case-Control Studies; D003080:Cold Temperature / Q000009:adverse effects; D004198:Disease Susceptibility; D005239:Fear; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000523:psychology*; D016584:Panic Disorder / Q000145:classification / Q000503:physiopathology*