title: ARDS in a patient with homozygous beta-thalassemia due to yersiniosis.
abstract: We report a case of Yersinia enterocolitica sepsis syndrome and the acute respiratory distress syndrome in a chronically transfused adolescent with beta-thalassemia. This manifestation of serious Y. enterocolitica infection has not previously been reported. Dyspnea, hypoxia, and fever were the principal features of the clinical presentation. The acute onset of respiratory symptoms occurred after appendectomy. Chest radiographs revealed frontal bilateral infiltrates and alveolar consolidation to three quadrants. Y. enterocolitica was identified from blood and intraoperative appendix cultures. Although there was no need for mechanical ventilation, a remarkable persistence of clinical and X-ray findings was noted. Therapy with high levels of oxygen, and intravenous amikacin and piperacillin/tazobactam led to a favorable outcome.
authors: Critical Care Department, Aghia Sophia Children's Hospital, Athens, Greece.
authors: P
authors: P
authors: Mavrommati
authors: V
authors: V
authors: Ladis
authors: E
authors: E
authors: Lagona
authors: M
authors: M
authors: Giannaki
authors: A
authors: A
authors: Raftopoulou
authors: T
authors: T
authors: Hatzis
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001062:Appendectomy; D005260:Female; D006801:Humans; D011183:Postoperative Complications / Q000382:microbiology; D011859:Radiography; D012128:Respiratory Distress Syndrome / Q000000981:diagnostic imaging / Q000209:etiology*; D018746:Systemic Inflammatory Response Syndrome / Q000188:drug therapy / Q000382:microbiology; D015009:Yersinia Infections / Q000150:complications* / Q000188:drug therapy; D015008:Yersinia enterocolitica / Q000302:isolation & purification*; D017086:beta-Thalassemia / Q000150:complications*
chemical_list: D000900:Anti-Bacterial Agents