Congenital varicella syndrome: cranial MRI in a long-term survivor.
Congenital varicella syndrome is a rare disorder which follows maternal infection in the first or early second trimester. The syndrome comprises a number of malformations including microcephaly, cortical destruction and limb hypoplasia. We describe a case where there has been long-term survival following second trimester maternal infection. The clinical findings, including the characteristic lower limb hypoplasia, are documented, as are the appearances on cranial MRI indicating an encephaloclastic porencephaly.
Deasy
N P
NP
Department of Neuroradiology, Ruskin Wing, King's College Hospital, London, UK.
Jarosz
J M
JM
Cox
T C
TC
Hughes
E
E
D000015:Abnormalities, Multiple / Q000175:diagnosis* / Q000473:pathology / Q000821:virology; D000293:Adolescent; D001921:Brain / Q000002:abnormalities*; D002644:Chickenpox / Q000151:congenital*; D005260:Female; D006801:Humans; D007866:Leg / Q000002:abnormalities; D008279:Magnetic Resonance Imaging; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012886:Skull / Q000473:pathology*; D017741:Survivors