title: Major vascular surgery in a patient with sickle cell disease.
abstract: We report a patient with homozygous sickle cell disease who underwent femoropopliteal bypass for claudication on walking 10m. Isotope studies showed a blood flow in his left femoral artery of only 0.808 ml. 100ml.min-1. The potential problems of sickle cell disease combined with peripheral vascular disease were probably reduced in this patient because he had an increased fetal haemoglobin level of 13%. Despite the femoral artery being clamped for 100 min, no sickling crisis occurred.
authors: Department of Anaesthetics, St James's University Hospital, Leeds, UK.
authors: A J
authors: AJ
authors: Vipond
authors: L D
authors: LD
authors: Caldicott
mesh_terms: D000368:Aged; D000755:Anemia, Sickle Cell / Q000150:complications*; D000768:Anesthesia, General / Q000379:methods; D019917:Blood Vessel Prosthesis Implantation; D000075202:Contraindications; D006801:Humans; D007383:Intermittent Claudication / Q000601:surgery*; D008297:Male; D012307:Risk Factors; D014111:Tourniquets