[Recurrent subacute encephalopathy in the framework of idiopathic hypereosinophilic syndrome].
METHODS
An 81-year-old man, previously good health, suddenly developed confusion and rapidly progressive severe tetraparesis.


METHODS
Peripheral blood and bone marrow revealed marked eosinophilia: allergic, parasitic, neoplastic or vasculitic causes were excluded. Magnetic resonance imaging demonstrated multiple lesions in the cortical and subcortical white matter.


METHODS
The findings indicated idiopathic hypereosinophilic syndrome involving the central nervous system and treatment with high doses of glucocorticoids was started. After a stormy course almost complete recovery occurred.


CONCLUSIONS
Idiopathic hypereosinophilic syndrome can rarely manifest itself a an isolated severe subacute encephalopathy.
Balestra
B
B
Medizinische Abteilung, Ospedale della Beata Vergine, Mendrisio.
Pedrazzi
P
P
Regli
F
F
D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001927:Brain Diseases / Q000175:diagnosis* / Q000188:drug therapy; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D013997:Time Factors
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D011241:Prednisone; D008775:Methylprednisolone