title: MRI of liver metastases: limitation of spleen-liver model in optimizing pulse sequences.
abstract: The spleen-liver model, as a predictor for contrast-to-noise ratio (C/N) in liver metastases, was verified for seven sequences in 22 patients with 70 colorectal metastases. Optimization of conventional spin-echo, T1-magnetization-prepared gradient-echo and fat frequency-selective presaturation inversion-recovery fast spin echo can be done using the spleen-liver model. C/N of liver-spleen and liver-metastases, however, differed significantly on our T1 gradient-echo and T2-weighted fast spin-echo images, with and without fat-selective saturation.
authors: Department of Radiology, Leiden University Medical Center, The Netherlands.
authors: J L
authors: JL
authors: Turkenburg
authors: M E
authors: ME
authors: Pijl
authors: E L
authors: EL
authors: van Persijn van Meerten
authors: J
authors: J
authors: Hermans
authors: J L
authors: JL
authors: Bloem
mesh_terms: D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000556:secondary*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D013154:Spleen / Q000473:pathology*