title: Risk factors for recurrent and residual cholesteatoma in children determined by second stage operation.
abstract: OBJECTIVE
  To clarify the risk factors for the development of recurrent and residual cholesteatoma in children.
  
  
  METHODS
  We studied 84 ears of 83 children aged 10 years or younger who underwent a second stage operation 1 year after primary surgery with a canal wall reconstruction procedure, and analyzed the clinical risk factors for recurrent and residual cholesteatoma.
  
  
  RESULTS
  Recurrent cholesteatoma was detected in 21 ears (25%) and residual cholesteatoma was noted in 35 (42%) of 84 ears. With respect to recurrent cholesteatoma, significant risk factors were determined to be male gender, pars flaccida type of cholesteatoma and the association of otitis media with effusion either in the side affected by cholesteatoma or on the opposite side. On the other hand, congenital type of cholesteatoma was a significant negative risk factor. With respect to residual cholesteatoma, the only risk factor was a posterosuperior type of cholesteatoma. Residual cholesteatoma was sometimes found even when the surgeon had declared complete removal of the cholesteatoma matrix at the time of primary surgery.
  
  
  CONCLUSIONS
  High incidence of recurrent and residual cholesteatoma was noted at the second stage operation. Occurrence of recurrent cholesteatoma is closely related to eustachian tube dysfunction. Thin and highly proliferative cholesteatoma matrix in children may be responsible for high occurrence of residual cholesteatoma. Therefore, planned staged surgery is preferable to single stage surgery for the treatment of pediatric cholesteatoma.
authors: Department of Otolaryngology, Teikyo University School of Medicine, Tokyo, Japan.
authors: Y
authors: Y
authors: Iino
authors: Y
authors: Y
authors: Imamura
authors: C
authors: C
authors: Kojima
authors: S
authors: S
authors: Takegoshi
authors: J I
authors: JI
authors: Suzuki
mesh_terms: D002648:Child; D002675:Child, Preschool; D018424:Cholesteatoma, Middle Ear / Q000453:epidemiology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D010034:Otitis Media with Effusion / Q000453:epidemiology; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors