The effect of hypoglycemic seizures on cognitive function in children with diabetes: a 7-year prospective study.
Sixteen children with insulin-dependent diabetes mellitus were evaluated at diagnosis and after 1, 3, and 7 years. They showed significant declines in verbal but not visuospatial abilities, particularly if they had any seizures from hypoglycemia. At the 7-year assessment those with hypoglycemic seizures showed deficits on perceptual, motor, memory, and attention tasks.
Rovet
J F
JF
Hospital for Sick Children and The University of Toronto, Toronto, Ontario, Canada.
Ehrlich
R M
RM
D000293:Adolescent; D000704:Analysis of Variance; D002648:Child; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000150:complications*; D008297:Male; D008568:Memory; D010465:Perception; D011446:Prospective Studies; D011597:Psychomotor Performance; D012640:Seizures / Q000150:complications / Q000209:etiology*; D014888:Wechsler Scales