In vitro effects of cadmium and DDVP (dichlorvos) on intestinal carbohydrase and protease activities in freshwater teleosts.
In vitro effects of cadmium (0.5-50 mg/l) and DDVP (0.2-100 mg/l) on the total amylolytic, sucrase and protease activities of intestinal mucosa have been studied for the first time in 11 freshwater teleosts. Total amylolytic activity in burbot, crucian carp and common carp, sucrase activity in blue bream and total proteolytic activity in burbot and pike were significantly decreased by cadmium at 50 mg/l. DDVP (at 0.2 mg/l) caused a significant decrease in total proteolytic activity in pike but had no effect on either protease or carbohydrase activities in other fish species.
Golovanova
I L
IL
Institute of Biology of Inland Waters, Russian Academy of Sciences, Borok, Yaroslavl Region, Russia. golovan@ibiw.yaroslavl.su
Kuz'mina
V V
VV
Gobzhelian
T E
TE
Pavlov
D F
DF
Chuiko
G M
GM
D000818:Animals; D002104:Cadmium / Q000008:administration & dosage / Q000494:pharmacology*; D002347:Carps / Q000378:metabolism; D004006:Dichlorvos / Q000008:administration & dosage / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D010450:Endopeptidases / Q000378:metabolism*; D017859:Esocidae / Q000378:metabolism; D005399:Fishes / Q000378:metabolism*; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006054:Goldfish / Q000378:metabolism; D007422:Intestines / Q000201:enzymology*; D011480:Protease Inhibitors / Q000494:pharmacology
D011480:Protease Inhibitors; D002104:Cadmium; D004006:Dichlorvos; D006026:Glycoside Hydrolases; C019822:carbohydrase; D010450:Endopeptidases