Haemagglutination and haemolysis by oral Fusobacterium nucleatum.
Haemagglutination and haemolytic activity of 80 Fusobacterium nucleatum isolates from human and animal origin, on different human blood types was evaluated. All the isolates were able to agglutinate erythrocytes and the most were either alpha-haemolytic or beta-haemolytic. No specificity between haemolysin or haemagglutinin and blood type was observed. Haemagglutination activity was inhibited when D-galactose, D-lactose or D-raffinose were used. Haemagglutination and haemolysis may be important factors in the pathogenesis of human and animal periodontal diseases.
Gaetti-Jardim Júnior
E
E
Department of Microbiology, University of São Paulo, Brazil.
Avila-Campos
M J
MJ
D000818:Animals; D001789:Blood Group Antigens / Q000502:physiology; D002428:Cebus / Q000097:blood / Q000382:microbiology; D004912:Erythrocytes / Q000502:physiology*; D016967:Fusobacterium nucleatum / Q000502:physiology*; D006384:Hemagglutination; D006461:Hemolysis; D006801:Humans; D008992:Monkey Diseases / Q000382:microbiology; D009055:Mouth / Q000382:microbiology
D001789:Blood Group Antigens