Effects of vitamin C supplementation on plasma antioxidant status in unfed periods.
In this study, the antioxidant protection of ascorbic acid (AA) supplementation during different unfed periods (24, 48, 120 h) was determined with blood lipid peroxidation level (thiobarbituric acid reactive substances, TBARS) and compared with plasma antioxidant sulfydryl group (RSH) content. Weight loss was induced by increasing the unfed period together with vitamin C supplementation. Blood AA levels decreased by starvation but increased by vitamin C supplementation. RSH content in plasma also decreased with the unfed period; these decreases became apparent by vitamin C supplementation. TBARS formation increased significantly by AA supplementation in the 120-h starvation period.
Gönül
B
B
Department of Physiology, Gazi University Faculty of Medicine, Beşevler, Ankara, Turkey.
Kaplan
B
B
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001205:Ascorbic Acid / Q000494:pharmacology*; D001835:Body Weight / Q000187:drug effects; D019587:Dietary Supplements / Q000009:adverse effects; D006168:Guinea Pigs; D015227:Lipid Peroxidation / Q000187:drug effects*; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
D000975:Antioxidants; D017392:Thiobarbituric Acid Reactive Substances; D001205:Ascorbic Acid