Histological study of periapical tissue healing in the rat molar after retrofilling with various materials.
We histologically examined the effects on the periapical tissue of various dental filling materials applied as retrofillings in rats and compared them with those of amalgam. The 4-META-TBB resin Superbond and the light-cured composite resin produced the least severe inflammatory reaction, with the greatest amount of new bone. In these specimens, regeneration of a part of the periodontal ligament was also observed. These results indicate that these materials might be very biocompatible and thus foster the natural regeneration of the periapical tissue.
Maeda
H
H
Department of Operative Dentistry and Endodontology, Faculty of Dentistry, Kyushu University, Fukuoka, Japan.
Hashiguchi
I
I
Nakamuta
H
H
Toriya
Y
Y
Wada
N
N
Akamine
A
A
D000818:Animals; D001047:Apicoectomy; D001672:Biocompatible Materials / Q000633:toxicity; D003723:Dental Amalgam / Q000633:toxicity; D005899:Glass Ionomer Cements / Q000633:toxicity; D008297:Male; D010486:Periapical Tissue / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012184:Retrograde Obturation; D012387:Root Canal Filling Materials / Q000633:toxicity*; D014945:Wound Healing / Q000187:drug effects*; D015035:Zinc Oxide-Eugenol Cement / Q000633:toxicity
D001672:Biocompatible Materials; D005899:Glass Ionomer Cements; D012387:Root Canal Filling Materials; D015035:Zinc Oxide-Eugenol Cement; D003723:Dental Amalgam