A new system to supply carbon dioxide safely to glaucoma patients.
OBJECTIVE
To develop a new system for safely supplying carbon dioxide (CO2) to open-angle glaucoma patients.


METHODS
The orbital hemodynamics of 7 glaucoma patients were determined by color Doppler imaging under baseline conditions and during CO2 supplementation sufficient to increase the end-tidal CO2 partial pressure by 10%. Systemic conditions, including oxygen saturation and blood pressure, were monitored throughout the CO2 inhalation.


RESULTS
Our results demonstrate that this new system enables us to supply CO2 in a safe, controlled manner to glaucoma patients.


CONCLUSIONS
This new system will be useful for investigating the effects of vasodilation by CO2 on orbital blood flow.
Niwa
Y
Y
Department of Ophthalmology, Gifu University School of Medicine, Japan.
Harris
A
A
Kagemann
L
L
Yamamoto
T
T
Matsubara
M
M
Takahashi
Kitazawa
Y
Y
D000280:Administration, Inhalation; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001783:Blood Flow Velocity / Q000187:drug effects; D002245:Carbon Dioxide / Q000008:administration & dosage* / Q000627:therapeutic use; D002908:Chronic Disease; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009880:Ophthalmic Artery / Q000000981:diagnostic imaging / Q000187:drug effects; D009915:Orbit / Q000098:blood supply; D012121:Respiration, Artificial / Q000295:instrumentation*; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler; D014664:Vasodilation / Q000187:drug effects; D012122:Ventilators, Mechanical
D002245:Carbon Dioxide