title: Spontaneous dural sinus thrombosis in children.
abstract: The clinical course of spontaneous dural sinus thrombosis in children varies from indolent to fulminant. Although many different etiologies for the development of dural sinus thrombosis have been described, a full recovery can be anticipated in most children following rehydration and the administration of systemic antibiotics. Steroids, systemic anticoagulation and intrasinus thrombolysis may be beneficial in selected patients, although the efficacy of these therapies has not been established prospectively in children. We reviewed 12 pediatric patients with spontaneous dural sinus thrombosis (1978-1998) to determine the etiology, clinical course and best treatment options. In the absence of a hypercoagulable state, pediatric patients generally recover well with rehydration and antibiotics and do not require anticoagulation.
authors: Department of Neurosurgery, The University of Mississippi Medical Center, Jackson, Miss., USA. jlanco@childmed.dallas.tx.us
authors: J A
authors: JA
authors: Lancon
authors: K R
authors: KR
authors: Killough
authors: R E
authors: RE
authors: Tibbs
authors: A I
authors: AI
authors: Lewis
authors: A D
authors: AD
authors: Parent
mesh_terms: D000293:Adolescent; D000925:Anticoagulants / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000150:complications / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D004388:Dura Mater / Q000098:blood supply / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D010579:Petrous Bone / Q000098:blood supply* / Q000000981:diagnostic imaging; D011446:Prospective Studies; D011859:Radiography; D012851:Sinus Thrombosis, Intracranial / Q000150:complications / Q000473:pathology* / Q000601:surgery*; D016896:Treatment Outcome; D014432:Tympanic Membrane / Q000098:blood supply / Q000000981:diagnostic imaging
chemical_list: D000925:Anticoagulants