V(O2) recovery kinetics in the horse following moderate, heavy, and severe exercise.
At the onset of exercise, horses exhibit O2 uptake (VO2) kinetics that are qualitatively similar to those of humans. In humans, there is a marked dissymmetry between on- and off-kinetics for VO2. This investigation sought to formally characterize the off-transient (recovery) VO2 kinetics in the horse within the moderate (M), heavy (H), and severe (S) exercise domains. Six horses were run on a high-speed treadmill at M, H, and S exercise intensities (i.e., that speed which yielded approximately 50, 85, 100% peak VO2, respectively, on the maximal incremental test). The time courses for the recovery were modeled by using a three-phase model with a single-exponential (fast component) or double-exponential (fast and slow component) phase 2. The single-exponential phase 2 model provided an excellent fit to the off-transient data, with the exception of one horse in the H domain which was best modeled by a double exponential. The time delay elicited no domain dependency (M, 18.0 +/- 1.0; H, 17.6 +/- 1.1; S, 17.8 +/- 2.0 s; P > 0.05), as was the case for the fast-component time constants (M, 16.3 +/- 2.0 s; H, 13.5 +/- 1.0 s; S, 14.6 +/- 0.3 s; P > 0.05). In the H and S (but not M) domains, the VO2 following resolution of the fast component was elevated above the preexercise baseline (H, 3.0 +/- 1.0 l/min; S, 5.7 +/- 1.1 l/min). This additional postexercise VO2 was correlated to the end-exercise increase in lactate (r = 0.94, P < 0.001) but not the end-exercise pulmonary arterial blood temperature (r = 0.45, P > 0.05). These data indicate that the time delay and subsequent kinetic response of the primary (fast-component) phase of exercise VO2 recovery in the horse is independent of the preceding exercise-intensity domain. However, in the H and S domains, the fast component resolves to an elevated baseline.
Langsetmo
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Departments of Anatomy and Physiology and Kinesiology, Kansas State University, Manhattan, Kansas 66502-5602, USA.
Poole
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D000818:Animals; D001794:Blood Pressure; D006736:Horses / Q000502:physiology*; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000502:physiology; D010101:Oxygen Consumption; D010805:Physical Conditioning, Animal / Q000502:physiology*; D005082:Physical Exertion / Q000502:physiology*; D011651:Pulmonary Artery / Q000502:physiology; D012044:Regression Analysis; D013997:Time Factors