Percutaneous revascularization of atherosclerotic obstruction of aortic arch vessels.
OBJECTIVE
To compare stenting of aortic arch vessel obstruction with surgical therapy and to establish recommendations for treatment.


BACKGROUND
Though surgery has been considered to be the procedure of choice for subclavian and brachiocephalic obstruction, little work has been done to compare it with stenting.


METHODS
Eighteen patients with symptomatic aortic arch vessel stenosis or occlusion were treated with stenting, followed by periodic clinical follow-up and noninvasive arterial Doppler studies. Data were compared with the results as shown in a systematic review of a published series of surgery and stenting procedures which included comparison of technical success, complications, mortality and patency.


RESULTS
Primary success in our series was 100% with improvement in mean stenosis from 84+/-11% to 1+/-5% and mean arm systolic blood pressure difference from 44+/-16 mm Hg to 3+/-3 mm Hg. There were no major complications (death, stroke, TIA, stent thrombosis or myocardial infarction). At follow-up (mean 17 months), all patients were asymptomatic with 100% primary patency. Literature review demonstrates equivalent patency and complications in the other published series of stenting. In contrast, there was a similar patency but overall incidence of stroke of 3+/-4% and death of 2+/-2% in the published surgical series.


CONCLUSIONS
Subclavian or brachiocephalic artery obstruction can be effectively treated by primary stenting or surgery. Comparison of stenting and the surgical experience demonstrates equal effectiveness but fewer complications and suggests that stenting should be considered as first line therapy for subclavian or brachiocephalic obstruction.
Hadjipetrou
P
P
Interventional Cardiovascular Medicine, Lahey Clinic, Medical Center, Burlington, Massachusetts 01805, USA.
Cox
S
S
Piemonte
T
T
Eisenhauer
A
A
D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D000800:Angioplasty, Balloon; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging; D001161:Arteriosclerosis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D001783:Blood Flow Velocity; D019917:Blood Vessel Prosthesis Implantation; D016122:Brachiocephalic Trunk / Q000000981:diagnostic imaging; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D015607:Stents; D013348:Subclavian Artery / Q000000981:diagnostic imaging; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler