Protease inhibitor-induced lipodystrophy.
The development of lipodystrophy as evidenced by central obesity, "moon facies," and a "buffalo hump" is a classical feature of Cushing's disease. Recently an association of "lipodystrophy" with the use of protease inhibitors has been reported. We describe a patient with lipodystrophy secondary to protease inhibitor therapy for HIV infection.
Williamson
K
K
Department of Medicine, University of Medicine and Dentistry of New Jersey/Robert Wood Johnson Medical School at Camden, USA.
Reboli
A C
AC
Manders
S M
SM
D005260:Female; D017320:HIV Protease Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D006679:HIV Seropositivity / Q000188:drug therapy*; D006801:Humans; D019469:Indinavir / Q000009:adverse effects* / Q000627:therapeutic use; D008060:Lipodystrophy / Q000139:chemically induced* / Q000175:diagnosis; D008875:Middle Aged; D009333:Neck
D017320:HIV Protease Inhibitors; D019469:Indinavir