Collagen: ubiquitous in nature, multifunctional in devices.
Collagen is a protein that is widely distributed in humans and plays an important role in many aspects of tissue performance. This versatility is central to the uses of collagen in biomedical devices. The structure and properties of collagen and the basis for their biomedical uses are described in this article.
Williams
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Clinical Engineering Department, Royal Liverpool University Hospital, UK. dfw.ce@liverpool.ac.uk
D000818:Animals; D001672:Biocompatible Materials; D001695:Biology; D001698:Biomedical Engineering; D003094:Collagen / Q000737:chemistry / Q000145:classification / Q000648:ultrastructure; D003238:Connective Tissue / Q000737:chemistry; D003461:Crystallography; D004548:Elasticity; D004563:Electrochemistry; D004867:Equipment Design; D004864:Equipment and Supplies; D016326:Extracellular Matrix Proteins / Q000737:chemistry; D005998:Glycine / Q000737:chemistry; D006801:Humans; D006909:Hydroxyproline / Q000737:chemistry; D011392:Proline / Q000737:chemistry; D013314:Stress, Mechanical; D013329:Structure-Activity Relationship
D001672:Biocompatible Materials; D016326:Extracellular Matrix Proteins; D003094:Collagen; D011392:Proline; D006909:Hydroxyproline; D005998:Glycine