Effect of parsley (Petroselinum crispum) on the skin of STZ induced diabetic rats.
Parsley (Petroselinum crispum) is one of the medicinal herbs used by diabetics in Turkey and it has been reported to reduce blood glucose. The purpose of this study therefore was to investigate the effect of feeding parsley on diabetes induced impairments in rat skins. Uncontrolled induced diabetes caused significant increases in nonenzymatic glycosylation of skin proteins, lipid peroxidation and blood glucose. Administration of parsley extract did not inhibit these effects except for the increase in blood glucose. SDS-polyacrylamide gel electrophoresis revealed no significant differences in any protein bands between any of the groups.
Tunali
T
T
Department of Biochemistry, Faculty of Dentistry, Marmara University, Nişantaşi, Turkey.
Yarat
A
A
Yanardağ
R
R
Ozçelik
F
F
Ozsoy
O
O
Ergenekon
G
G
Emekli
N
N
D000818:Animals; D019661:Apiaceae / Q000627:therapeutic use; D001786:Blood Glucose / Q000187:drug effects; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000378:metabolism* / Q000628:therapy; D003922:Diabetes Mellitus, Type 1 / Q000139:chemically induced / Q000378:metabolism* / Q000628:therapy; D004591:Electrophoresis, Polyacrylamide Gel; D006031:Glycosylation / Q000187:drug effects; D007004:Hypoglycemic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D051381:Rats; D012867:Skin / Q000187:drug effects*; D013311:Streptozocin; D014421:Turkey
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D013311:Streptozocin