title: Streptomycin perfusion of the labyrinth in the treatment of Menière's disease: a modified technique.
abstract: The ideal surgical procedure for Menière's disease would combine the high rate of vertigo control and the good hearing preservation of vestibular nerve section with the low morbidity of labyrinthectomy. Shea's technique of streptomycin perfusion of the labyrinth has been modified by making an additional opening into the posterior semicircular canal in an effort to limit the amount of streptomycin going into the cochlea. Seventeen patients with definite Menière's with poor hearing have had this procedure. Vertigo was controlled in 94% and the hearing preserved in 55%. Vestibular rehabilitation was not a problem. It is speculated that hearing preservation would be better if the procedure were not restricted to those with poor hearing. This method of destruction of the vestibular system carries the possibility of hearing preservation and maintains the possibility of cochlear implantation should this ever be required.
authors: Royal Victoria Hospital, Belfast, UK.
authors: R A
authors: RA
authors: Adair
authors: A G
authors: AG
authors: Kerr
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D007758:Ear, Inner / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000534:rehabilitation / Q000628:therapy*; D008875:Middle Aged; D018579:Patient Selection; D010477:Perfusion; D013307:Streptomycin / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D013307:Streptomycin