Advantage of intravenous anaesthesia for acute stage surgery of aneurysmal subarachnoid haemorrhage.
To investigate the clinical effects of intravenous anaesthesia on surgical procedure and the outcome in acute stage surgery for aneurysmal subarachnoid haemorrhage (SAH), pre-, intra-, and post-operative factors were analyzed to compare between inhalational (IA, n = 38) and intravenous (IVA, n = 37) anaesthesia. IVA significantly shortened the duration of surgery (p < 0.05) and the duration of hospital stay (p < 0.01). These results suggest that IVA may be more suitable than IA for acute stage surgery of aneurysmal SAH. These effects may be mainly caused by IVA's pharmakokinetics, by effects on intracranial homeostasis and metabolism, and neuroprotective properties.
Sato
K
K
Department of Neuroanesthesia, Kohnan Hospital, Sendai, Japan.
Karibe
H
H
Yoshimoto
T
T
D000208:Acute Disease; D000769:Anesthesia, Inhalation; D000771:Anesthesia, Intravenous; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D002532:Intracranial Aneurysm / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology; D013345:Subarachnoid Hemorrhage / Q000601:surgery*; D016896:Treatment Outcome