title: United Kingdom Prospective Diabetes Study (UKPDS). Effects of glucose and blood pressure control on complications of type 2 diabetes mellitus.
abstract: The United Kingdom Prospective Diabetes Study (UKPDS) showed that intensive treatment (i.e., glucose-lowering drugs, with a goal fasting blood glucose level of 108 mg/dL) decreases the microvascular complications of type 2 diabetes mellitus. We summarize the key study results and their implications for clinical management of type 2 diabetes mellitus.
authors: Department of Endocrinology and Metabolism, Cleveland Clinic, USA.
authors: C E
authors: CE
authors: Nasr
authors: B J
authors: BJ
authors: Hoogwerf
authors: C
authors: C
authors: Faiman
authors: S S
authors: SS
authors: Reddy
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000378:metabolism / Q000517:prevention & control*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000517:prevention & control*; D008875:Middle Aged; D009765:Obesity / Q000150:complications* / Q000517:prevention & control*; D018579:Patient Selection; D011446:Prospective Studies; D016896:Treatment Outcome; D006113:United Kingdom
chemical_list: D001786:Blood Glucose