Signalling pathways in two-component phosphorelay systems.
Two-component systems are characterized by phosphotransfer reactions involving histidine and aspartate residues in highly conserved signalling domains. Although the basic principles of signal transduction by these systems have been elucidated, several important aspects, such as their integration into more complex cellular regulatory networks and the molecular basis of the specificity of signal transduction, remain unknown.
Perraud
A L
AL
Lehrstuhl für Mikrobiologie, Theodor-Boveri-Institut, Universität Würzburg, Germany.
Weiss
V
V
Gross
R
R
D000818:Animals; D006639:Histidine / Q000378:metabolism*; D010770:Phosphotransferases / Q000378:metabolism*; D015398:Signal Transduction
D006639:Histidine; D010770:Phosphotransferases