title: Rehabilitation with dental implants of oral cancer patients.
abstract: The aim of this study was to evaluate the risks and complications of rehabilitation with dental implants after tumour surgery and radiotherapy. After a disease-free survival of 18 months, 29 patients who had undergone oral cancer treatment were rehabilitated with dental implants. The complication rate of implants in irradiated, non-irradiated and grafted bone was analyzed at least 3 years after implant placement. In the healing period, 28.6% of the implants in irradiated bone and 8.4% in non-irradiated bone showed soft tissue complications. Of the implants, 26.7% in the irradiated and 14.7% in the non-irradiated mandibular bone were lost in the first 36 months after placement. Thirty-one point two percent of implants inserted in non-irradiated bone grafts were affected and did not osseointegrate. Of 109 inserted implants, 70 were suitable for prosthetic rehabilitation. There are high complication rates after implant placement in oral cancer patients. Irradiation adversely affects soft tissue healing. Osseointegration is frequently disturbed, especially when implants were placed in non-vascularized bone grafts.
authors: Department of Oral and Maxillofacial Surgery, University of Münster, Germany.
authors: R
authors: R
authors: Werkmeister
authors: D
authors: D
authors: Szulczewski
authors: P
authors: P
authors: Walteros-Benz
authors: U
authors: U
authors: Joos
mesh_terms: D000328:Adult; D000368:Aged; D016025:Bone Transplantation; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000534:rehabilitation* / Q000601:surgery; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D019094:Dental Prosthesis, Implant-Supported; D019232:Dental Restoration Failure; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008334:Mandible / Q000528:radiation effects / Q000601:surgery*; D008875:Middle Aged; D009059:Mouth Diseases / Q000209:etiology; D009061:Mouth Mucosa / Q000528:radiation effects / Q000601:surgery; D009062:Mouth Neoplasms / Q000532:radiotherapy / Q000534:rehabilitation* / Q000601:surgery; D016348:Osseointegration; D013524:Surgical Flaps; D014945:Wound Healing
chemical_list: D015921:Dental Implants