Central effects of AC-1 and TFG-1.
AC-1 and TFG-1 are both herb extracts from Avena Sativa and Trigonella Foenum Graecum respectively. In folk medicine, Trigonella Foenum Graecum is used as appetiser and general tonic as well as for pellagra treatment and for treatment of pulmonary disorders. Avena Sativa is another commonly used appetiser and tonic. In our study we examined the influence of AC-1 and TFG-1 on some of the major functions of the central nervous system. We divided the test animals in three groups and after administering the herb extracts we monitored different pharmacological parameters-Phenamine toxicity and stereotypy, Hexobarbital sleep, elementary conditioned reflexes and antiseizure activity.
Balabanov
P
P
Department of Pharmacology and Drug Toxicology, Higher Medical Institute, Plovdiv, Bulgaria.
Karamanos
A P
AP
D000661:Amphetamine / Q000633:toxicity; D000818:Animals; D018554:Avena; D002490:Central Nervous System / Q000187:drug effects*; D006801:Humans; D019684:Magnoliopsida; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D012018:Reflex / Q000187:drug effects; D013239:Stereotyped Behavior / Q000187:drug effects
D010936:Plant Extracts; D000661:Amphetamine