Squamous cell carcinoma of the tongue in a patient with Rothmund-Thomson syndrome.
Rothmund-Thomson syndrome is a rare autosomal recessive genodermatosis characterised by poikilodermatous skin changes that appear in childhood. Patients exhibit variable additional features including juvenile cataracts, skeletal abnormalities and a higher than expected incidence of malignancies. We report a case of squamous cell carcinoma of the tongue in a 37-year-old Rothmund-Thomson syndrome patient and review the natural history of this rare disease, given that the patient was diagnosed with Rothmund-Thomson syndrome at the age of 8 years and was first reported in 1975.
Marín-Bertolín
S
S
Department of Plastic and Reconstructive Surgery, Valencia University General Hospital, Spain.
Amorrortu-Velayos
J
J
Aliaga Boniche
A
A
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011038:Rothmund-Thomson Syndrome / Q000150:complications*; D014062:Tongue Neoplasms / Q000209:etiology* / Q000473:pathology