[Molecular genetic aspects of neoplasms].
The paper presents data on the role of some genes that provide normal positive and negative regulation of cell proliferation. It considers their structural and functional changes that lead to the occurrence and progression of tumors. The characteristics of tumor suppressive genes whose inactivation determines hereditary predisposition to some forms of malignant neoplasms.
Gar'kavtseva
R F
RF
Gar'kavtsev
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D014408:Biomarkers, Tumor; D002455:Cell Division / Q000235:genetics; D005260:Female; D016147:Genes, Tumor Suppressor / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D009154:Mutation / Q000235:genetics; D009369:Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D011519:Proto-Oncogenes / Q000235:genetics*
D014408:Biomarkers, Tumor