title: Nerve growth factor acts via retinoic acid synthesis to stimulate neurite outgrowth.
authors: J
authors: J
authors: Corcoran
authors: M
authors: M
authors: Maden
mesh_terms: D000445:Aldehyde Oxidoreductases / Q000096:biosynthesis / Q000235:genetics; D000818:Animals; D004268:DNA-Binding Proteins / Q000502:physiology; D004221:Disulfiram / Q000494:pharmacology; D005727:Ganglia, Spinal / Q000166:cytology / Q000187:drug effects; D051379:Mice; D009414:Nerve Growth Factors / Q000494:pharmacology / Q000502:physiology*; D009416:Nerve Regeneration / Q000187:drug effects; D009419:Nerve Tissue Proteins / Q000502:physiology*; D016501:Neurites / Q000502:physiology*; D057105:Nuclear Receptor Subfamily 4, Group A, Member 1; D009924:Organ Culture Techniques; D010084:Oxidation-Reduction; D016716:PC12 Cells; D051381:Rats; D018160:Receptors, Cytoplasmic and Nuclear; D018168:Receptors, Retinoic Acid / Q000096:biosynthesis / Q000235:genetics; D011987:Receptors, Steroid; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis / Q000235:genetics; D050697:Retinal Dehydrogenase; D012172:Retinaldehyde / Q000378:metabolism; D014157:Transcription Factors / Q000502:physiology; D014212:Tretinoin / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D004268:DNA-Binding Proteins; D009414:Nerve Growth Factors; D009419:Nerve Tissue Proteins; C539818:Nr4a1 protein, mouse; C539820:Nr4a1 protein, rat; D057105:Nuclear Receptor Subfamily 4, Group A, Member 1; D018160:Receptors, Cytoplasmic and Nuclear; D018168:Receptors, Retinoic Acid; D011987:Receptors, Steroid; D011993:Recombinant Fusion Proteins; D014157:Transcription Factors; C082925:retinoic acid receptor beta; D014212:Tretinoin; D000445:Aldehyde Oxidoreductases; D050697:Retinal Dehydrogenase; D012172:Retinaldehyde; D004221:Disulfiram