Functional diversity in the dynamin family.
The function of the GTPase dynamin has been discussed for several years. It clearly plays a role in vesicle budding, but, despite recent insights, precisely how it functions in this process is still a matter of debate. In addition, it is now clear that dynamin is a member of a large protein family, present in a variety of cellular locations where members apparently perform a range of functions. This article describes current understanding of the structure and function of the various dynamin family members.
van der Bliek
A M
AM
Dept of Biological Chemistry, UCLA School of Medicine 90095-1737, USA. avan@mednet.ucla.edu
D000595:Amino Acid Sequence; D000818:Animals; D034281:Dynamins; D020558:GTP Phosphohydrolases / Q000145:classification / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008969:Molecular Sequence Data
D020558:GTP Phosphohydrolases; D034281:Dynamins