Benfluorex: what use? A second look. Poor assessment file.
The clinical file on the value of benfluorex for hypertriglyceridaemia is highly inadequate.  No clinical trials have been done with morbidity or mortality as end points.  Available placebo-controlled trials are small, methodologically weak in most cases, and their results regarding triglyceride levels are contradictory.  None of the three trials comparing benfluorex with a fibrate is interpretable, because of methodological problems.
D000144:Acids, Acyclic / Q000627:therapeutic use; D001067:Appetite Depressants / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005277:Fenfluramine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005602:France; D006801:Humans; D015228:Hypertriglyceridemia / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D010919:Placebos; D016896:Treatment Outcome; D014481:United States
D000144:Acids, Acyclic; D001067:Appetite Depressants; D000960:Hypolipidemic Agents; D010919:Placebos; D005277:Fenfluramine