Role of the enterohepatic circulation of bile salts in lipoprotein metabolism.
The enterohepatic circulation of bile salts and cholesterol plays a central role in maintaining whole body cholesterol homeostasis. Hepatic lipoprotein metabolism is reviewed and the role of disturbances in bile salt metabolism in the pathogenesis of dyslipidemias is discussed. Further, the manipulation of bile salt metabolism to treat dyslipidemia is reviewed.
Cooper
A D
AD
Research Institute, Palo Alto Medical Foundation, California, USA.
D001647:Bile Acids and Salts / Q000378:metabolism* / Q000627:therapeutic use; D004764:Enterohepatic Circulation / Q000502:physiology*; D006801:Humans; D008074:Lipoproteins / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008107:Liver Diseases / Q000188:drug therapy / Q000378:metabolism
D001647:Bile Acids and Salts; D008074:Lipoproteins