title: Memory guided saccade deficit after caudate nucleus lesion.
abstract: The role of the caudate nucleus in ocular motor control is not well determined in humans. Eye movements were recorded from a 45 year old man with infarctions involving bilaterally the body of the caudate nucleus, with a greater extent on the left side. The patient exhibited a pattern of eye movement abnormalities in which a delay dependent decrease of accuracy of memory guided saccades predominated. By contrast, memory guided pointing was normal. It is concluded that the body of the caudate nucleus participates in a spatial short term memory network devoted to eye movements.
authors: INSERM U 289, Hôpital de la Salpêtrière, Paris, France.
authors: A I
authors: AI
authors: Vermersch
authors: B M
authors: BM
authors: Gaymard
authors: S
authors: S
authors: Rivaud-Pechoux
authors: C J
authors: CJ
authors: Ploner
authors: Y
authors: Y
authors: Agid
authors: C
authors: C
authors: Pierrot-Deseilligny
mesh_terms: D000328:Adult; D002421:Caudate Nucleus / Q000473:pathology*; D006801:Humans; D006973:Hypertension / Q000150:complications; D002546:Ischemic Attack, Transient / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory; D008875:Middle Aged; D011699:Putamen / Q000473:pathology*; D011930:Reaction Time; D012438:Saccades