title: Callosal disconnection syndrome in a left-handed patient due to infarction of the total length of the corpus callosum.
abstract: We report on a left-handed patient with an ischemic infarction affecting exclusively the total length of the corpus callosum. This lesion clinically correlated with an almost complete callosal disconnection syndrome as described in callosotomy subjects, including unilateral verbal anosmia, hemialexia, unilateral ideomotor apraxia, unilateral agraphia, unilateral tactile anomia, unilateral constructional apraxia, lack of somesthetic transfer and dissociative phenomena. Despite the patient's left-handedness, his pattern of deficits was similar to the disconnection syndrome found in right-handers. Our report focusses on motor dominance and praxis. We followed-up the improvement in left apraxia and investigated the ability to initiate and learn a new visuo-motor skill. The results permit two tentative assumptions: (1) that the improvement in left apraxia was due to a compensatory increase in ipsilateral proximal muscle control, and (2) that motor dominance, i.e. the competence to initiate and learn a new movement pattern, was hemispherically dissociable from manual dominance in the sense of praxis control.
authors: Neurologische Klinik und Poliklinik, Universitätsklinikum Benjamin Franklin, der Freien Universität, Berlin.
authors: H
authors: H
authors: Lausberg
authors: R
authors: R
authors: Göttert
authors: U
authors: U
authors: Münssinger
authors: F
authors: F
authors: Boegner
authors: P
authors: P
authors: Marx
mesh_terms: D001072:Apraxias; D002545:Brain Ischemia / Q000503:physiopathology* / Q000523:psychology; D003337:Corpus Callosum / Q000473:pathology*; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009048:Motor Skills; D009483:Neuropsychological Tests; D013577:Syndrome