Invasive aspergillosis caused by Aspergillus ustus: case report and review.
A case of invasive pulmonary aspergillosis in an allogeneic bone marrow transplant recipient caused by Aspergillus ustus is presented. A. ustus was also recovered from the hospital environment, which may indicate that the infection was nosocomially acquired. A literature review revealed seven cases of invasive infections caused by A. ustus, and three of these were primarily cutaneous infections. In vitro susceptibility testing of 12 A. ustus isolates showed that amphotericin B and terbinafine had fungicidal activity and that itraconazole and voriconazole had fungistatic activity.
Verweij
P E
PE
Departments of Medical Microbiology, University Hospital Nijmegen, Nijmegen, The Netherlands. p.verweij@mmb.azn.nl
van den Bergh
M F
MF
Rath
P M
PM
de Pauw
B E
BE
Voss
A
A
Meis
J F
JF
D000328:Adult; D000946:Antigens, Fungal / Q000097:blood; D001228:Aspergillosis / Q000188:drug therapy / Q000209:etiology*; D001230:Aspergillus / Q000187:drug effects / Q000276:immunology / Q000302:isolation & purification*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests
D000946:Antigens, Fungal