Preoperative hypoglycaemia, propranolol and the Jervell and Lange-Nielsen syndrome.
The Jervell and Lange-Nielsen syndrome is an autosomal recessive trait characterized by deafness and electrocardiographic changes. These changes include prolongation of the QT interval and T-wave inversion. Treatment may include the use of beta-blockers to prevent the development of malignant ventricular arrhythmias and sudden death. We report a patient with this syndrome, who was receiving propranolol orally and who became hypoglycaemic during the preoperative fasting period prior to cochlear implantation.
Baines
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DB
Department of Anaesthesia, New Children's Hospital, Royal Alexandra Hospital for Children, Sydney NSW, Australia.
Murrell
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D
D000319:Adrenergic beta-Antagonists / Q000009:adverse effects* / Q000627:therapeutic use; D005215:Fasting; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced*; D007223:Infant; D008133:Long QT Syndrome / Q000188:drug therapy*; D008297:Male; D011300:Preoperative Care; D011433:Propranolol / Q000009:adverse effects* / Q000627:therapeutic use
D000319:Adrenergic beta-Antagonists; D011433:Propranolol