Atm haploinsufficiency results in increased sensitivity to sublethal doses of ionizing radiation in mice.
Barlow
C
C
Eckhaus
M A
MA
Schäffer
A A
AA
Wynshaw-Boris
A
A
D000375:Aging / Q000235:genetics / Q000528:radiation effects; D000818:Animals; D064007:Ataxia Telangiectasia Mutated Proteins; D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; D004307:Dose-Response Relationship, Radiation; D006200:Hair Color / Q000528:radiation effects; D006239:Haplotypes; D008136:Longevity / Q000235:genetics / Q000528:radiation effects; D051379:Mice; D008817:Mice, Mutant Strains / Q000235:genetics*; D009381:Neoplasms, Radiation-Induced / Q000235:genetics / Q000473:pathology; D017346:Protein Serine-Threonine Kinases; D011506:Proteins / Q000235:genetics* / Q000528:radiation effects; D011836:Radiation Tolerance / Q000235:genetics*; D015996:Survival Rate; D025521:Tumor Suppressor Proteins
D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; D011506:Proteins; D025521:Tumor Suppressor Proteins; D064007:Ataxia Telangiectasia Mutated Proteins; C576325:Atm protein, mouse; D017346:Protein Serine-Threonine Kinases