[Role of kallikrein-kinin system in pathogenesis of eye contusions].
Studies of the plasma components of the kallikrein-kinin system (KKS) in the lacrimal fluid (LF) of damaged eyeball of 32 patients hospitalized for contusion for the eyeball showed an appreciable increase of KKS activity during the first three days and its less expressed increase on days 10-19 after the injury. The content of prekallikrein in the damaged eye LF depends on the severity of eye contusion and plasma KKS status, and the levels of LF prekallikrein in the damaged and intact eye correlate. Serum kallikrein activity depends on the severity of injury.
Bendelik
E K
EK
Moshetova
L K
LK
Iarovaia
G A
GA
Dotsenko
V L
VL
Neshkova
E A
EA
Alekseev
I B
IB
Tabekova
T T
TT
D015415:Biomarkers; D003288:Contusions / Q000175:diagnosis / Q000378:metabolism*; D005123:Eye / Q000378:metabolism; D005131:Eye Injuries / Q000175:diagnosis / Q000378:metabolism*; D005500:Follow-Up Studies; D006801:Humans; D016234:Kallikrein-Kinin System / Q000502:physiology*; D007610:Kallikreins / Q000378:metabolism; D011288:Prekallikrein / Q000378:metabolism; D013666:Tears / Q000378:metabolism; D015599:Trauma Severity Indices; D014949:Wounds, Nonpenetrating / Q000175:diagnosis / Q000378:metabolism*
D015415:Biomarkers; D011288:Prekallikrein; D007610:Kallikreins