title: Synthesis and activity of cephalosporins containing an oxyiminomethylene functionality in the ortho-position of a phenyl- or phenoxyacetic acid C-7 side chain substituent.
abstract: A new series of cephalosporins having in the C-7 side chain a phenyl- or a phenoxyacetamido group bearing an oxyiminomethyl function in the ortho-position of the aromatic ring was prepared. Their in vitro activity was tested against both Gram+ and Gram- strains.
authors: Centro CNR, Milan, Italy.
authors: D
authors: D
authors: Albanese
authors: D
authors: D
authors: Landini
authors: M
authors: M
authors: Leone
authors: M
authors: M
authors: Penso
authors: M
authors: M
authors: Zenoni
mesh_terms: D002511:Cephalosporins / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D002511:Cephalosporins