title: Prenatal diagnosis of 46,XX male fetuses.
abstract: Ultrasonography can accurately determine phenotypic sex differences from those of the genetic sex. Two cases were identified; they were the result of a translocation of the SRY gene from the Y chromosome to the X chromosome during meiosis. An ultrasonographic difference may represent an otherwise unsuspected genetic abnormality.
authors: Department of Obstetrics and Gynecology, the Division of Medical Genetics, Northwestern Memorial Hospital, Chicago, Illinois, USA.
authors: N A
authors: NA
authors: Ginsberg
authors: A
authors: A
authors: Cadkin
authors: C
authors: C
authors: Strom
authors: E
authors: E
authors: Bauer-Marsh
authors: Y
authors: Y
authors: Verlinsky
mesh_terms: D000328:Adult; D000649:Amniocentesis; D004268:DNA-Binding Proteins / Q000235:genetics; D005260:Female; D006059:Gonadal Dysgenesis / Q000000981:diagnostic imaging* / Q000235:genetics; D006801:Humans; D007621:Karyotyping; D008297:Male; D009687:Nuclear Proteins; D010641:Phenotype; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012729:Sex Chromosome Aberrations / Q000000981:diagnostic imaging*; D051876:Sex-Determining Region Y Protein; D014157:Transcription Factors; D014178:Translocation, Genetic; D016216:Ultrasonography, Prenatal; D014960:X Chromosome
chemical_list: D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; C497745:SRY protein, human; D051876:Sex-Determining Region Y Protein; D014157:Transcription Factors