title: Treatment of achalasia: recent advances in surgery.
abstract: Achalasia is an uncommon motility disorder of the esophagus with an uncertain etiology. Considerable debate exists regarding the most effective treatment for long-term relief of symptoms. For decades, pneumatic dilatation has been the primary treatment option, and surgery was reserved for patients who required repeated dilations or for those who were not willing to undergo the risk of perforation associated with dilatation. Recently botulinum toxin injection of the lower esophageal sphincter has been shown to provide substantial short-term relief from dysphagia; however, its effect only lasts for a short period of time. Recently, minimally invasive surgical techniques have been developed to perform a Heller myotomy effectively with an antireflux procedure. This has become a primary treatment option for many patients. We present a review of the outcome of different therapeutic options of achalasia with a special focus on laparoscopic procedures.
authors: Department of Surgery, Mayo Clinic Jacksonville, FL 32224, USA.
authors: M H
authors: MH
authors: Seelig
authors: K R
authors: KR
authors: DeVault
authors: S K
authors: SK
authors: Seelig
authors: P J
authors: PJ
authors: Klingler
authors: S A
authors: SA
authors: Branton
authors: N R
authors: NR
authors: Floch
authors: T
authors: T
authors: Bammer
authors: R A
authors: RA
authors: Hinder
mesh_terms: D018726:Anti-Dyskinesia Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001905:Botulinum Toxins / Q000008:administration & dosage / Q000627:therapeutic use; D002404:Catheterization; D004931:Esophageal Achalasia / Q000628:therapy*; D004943:Esophagogastric Junction; D005500:Follow-Up Studies; D018662:Fundoplication / Q000379:methods; D006801:Humans; D007267:Injections; D010535:Laparoscopy / Q000379:methods; D012449:Safety; D016896:Treatment Outcome
chemical_list: D018726:Anti-Dyskinesia Agents; D001905:Botulinum Toxins