title: Clinical factors influencing periocular surgical defects after Mohs micrographic surgery.
abstract: OBJECTIVE
  To determine if the surgical defect after excision of periocular skin cancers can be predicted preoperatively.
  
  
  METHODS
  Review of medical records of patients who underwent excision of periocular skin cancers between 1990 and 1995.
  
  
  RESULTS
  Two hundred sixty-four patients (157 men, 107 women) with a total of 281 malignant tumors were treated. Basal cell carcinoma accounted for 92.2% of the tumors, whereas squamous cell carcinoma constituted 6.4% of lesions. The lower eyelid and medial canthus were the most frequent sites of involvement. Data analysis was conducted on tumor size, cell type, location, and the Mohs stages and sections that were required for cure. Morpheaform basal cell carcinomas required the most Mohs stages and sections and resulted in the largest excisional defects when compared with clinical tumor dimensions. The lateral canthus had the fewest tumors, but lesions in this area resulted in the largest excisional defects (mean, 9.5 cm2) when compared with lesions of the medial eyelid (p = 0.35). The average size of the defect after Mohs excision of basal cell carcinoma was 4.2 to 4.6 times the original clinical tumor size. For morpheaform basal cell carcinoma, however, the average excisional defect was 6.1 times larger. Conversely, the average defect after excision of squamous cell carcinoma was only 2.6 times as large as the original clinical tumor size.
  
  
  CONCLUSIONS
  These data are useful in predicting the size of a defect after Mohs excision of periocular skin cancer, based on the original clinical tumor size.
authors: Department of Ophthalmology, University of Iowa College of Medicine, University of Iowa Hospitals and Clinics, Iowa City 52242-1091, USA.
authors: K D
authors: KD
authors: Carter
authors: J A
authors: JA
authors: Nerad
authors: D C
authors: DC
authors: Whitaker
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019882:Blepharoplasty / Q000379:methods; D002280:Basal Cell Carcinoma / Q000473:pathology / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005142:Eyelid Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery / Q000009:adverse effects*; D009364:Neoplasm Recurrence, Local; D011183:Postoperative Complications / Q000601:surgery*; D012086:Reoperation; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome