Yeast cell permeabilizing beta-1,3-glucanases: A tool for the integration of downstream processes and metabolic engineering applications to yeast.
In this article, we consider the impact on downstream process design resulting from the use of metabolically engineered yeast strains. We address the issue of how manipulation of cell wall permeability can improve the release and subsequent recovery of heterologous products produced in yeast.
Ferrer
P
P
Center for Biochemical Engineering and Biotechnology, Department of Chemical Engineering, Universidad de Chile, Beauchef 861, Santiago, Chile. ferrer@uab-eq.uab.es
Diers
I
I
Asenjo
J A
JA
Andrews
B A
BA
D002463:Cell Membrane Permeability; D005818:Genetic Engineering / Q000379:methods*; D043326:Glucan 1,3-beta-Glucosidase; D006026:Glycoside Hydrolases / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000235:genetics; D015003:Yeasts / Q000201:enzymology* / Q000235:genetics*
D006026:Glycoside Hydrolases; D043326:Glucan 1,3-beta-Glucosidase; C117648:beta-1,3-exoglucanase