Ability of a rapid serology test to detect seroconversion to herpes simplex virus type 2 glycoprotein G soon after infection.
Sera (n = 188) from 29 patients with first-episode genital herpes simplex virus type 2 (HSV-2) infections were tested by POCkit-HSV-2 and Western blot (WB) to determine the speed of seroconversion. The median time to detection of HSV-2 antibody was 13 days (range, 3 to 102 days) by the POCkit-HSV-2 test versus 13 days (range, 2 to 58 days) for WB.
Ashley
R L
RL
Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA. rashle@chmc.org
Eagleton
M
M
Pfeiffer
N
N
D000914:Antibodies, Viral / Q000097:blood*; D015153:Blotting, Western; D018258:Herpesvirus 2, Human / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D013997:Time Factors; D014759:Viral Envelope Proteins / Q000276:immunology*
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D014759:Viral Envelope Proteins