Injury induces neuropsin mRNA in the central nervous system.
We have shown that neuropsin is expressed in the neurons of the limbic system in the adult mouse. After the central nervous system was injured by incision or intraperitoneal kainate injection, neuropsin mRNA was induced in the peri-lesioned region. The cells in which neuropsin mRNA was induced were localized mainly in axon fiber pathways and closely associated to proteolipid protein (PLP) mRNA expressing oligodendrocytes.
Tomizawa
K
K
Division of Structural Cell Biology, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0101, Japan.
He
X
X
Yamanaka
H
H
Shiosaka
S
S
Yoshida
S
S
D000818:Animals; D001930:Brain Injuries / Q000378:metabolism*; D017403:In Situ Hybridization; D007608:Kainic Acid / Q000494:pharmacology; D007610:Kallikreins; D051379:Mice; D012333:RNA, Messenger / Q000096:biosynthesis*; D012697:Serine Endopeptidases / Q000235:genetics*; D013119:Spinal Cord Injuries / Q000378:metabolism*
D012333:RNA, Messenger; C094799:KLK8 protein, human; D007610:Kallikreins; D012697:Serine Endopeptidases; D007608:Kainic Acid