[Profile of the resistance to macrolides and imidazoles of Helicobacter pylori in a sample of the Portuguese population].
We studied the sensitivity of H. pylori to clarithromycin and metronidazole, as well as the sensitivity and specificity of H. pylori culture, urease test and histology on a sample of 166 Portuguese patients. We observed a prevalence of 5.8% resistance to clarithromycin and 60% resistance to metronidazole. The sensitivity and specificity for the diagnostic tests were: culture 98% and 100%, urease test 98% and 91%, histology 50% and 95%, respectively.
Rosário
M
M
Serviço de Gastroenterologia, Instituto Clinico e Imunológico de Lisboa.
Caetano
J M
JM
Pessanha
M A
MA
Marote
G
G
da Silva
J A
JA
Caetano
J A
JA
D000900:Anti-Bacterial Agents / Q000037:antagonists & inhibitors*; D001706:Biopsy; D017291:Clarithromycin / Q000037:antagonists & inhibitors*; D004352:Drug Resistance, Microbial; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000382:microbiology / Q000473:pathology; D016480:Helicobacter pylori / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D008795:Metronidazole / Q000037:antagonists & inhibitors*; D008826:Microbial Sensitivity Tests; D012680:Sensitivity and Specificity; D013270:Stomach / Q000382:microbiology / Q000473:pathology
D000900:Anti-Bacterial Agents; D008795:Metronidazole; D017291:Clarithromycin