title: [Diabetes mellitus as a life-style related disease--importance of environmental factors on pathogenesis and progress of type-2 diabetes].
abstract: Onset and progress of several diseases common in adults such as diabetes mellitus, hyperlipidemia and hypertension are closely correlated with environmental factors. In recent years besides aging, lack of exercise, overweight, excess intake of fat and carbohydrates are recognized to be increasingly important to develop so called life-style related diseases especially in type 2 diabetes. The system of the insulin action from the biosynthesis of insulin and excretion in the pancreatic beta cells to receptor and insulin signal transmissions is often influenced by unfavorable life style in the modernized era. Either for primary or for secondary prevention, education not only in patients but in general public must be extensively conducted.
authors: Saiseikai Diabetes Center, Tokyo.
authors: K
authors: K
authors: Matsuoka
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology*; D018450:Disease Progression; D006801:Humans; D008019:Life Style; D012307:Risk Factors