title: The Tridimensional Personality Questionnaire as a predictor of relapse in detoxified alcohol dependents. The European Fluvoxamine in Alcoholism Study Group.
abstract: Personality traits have been found as strong predictors for treatment response in different psychiatric disorders. We administered the Tridimensional Personality Questionnaire, which measures the three personality dimensions: novelty seeking, harm avoidance (HA), and reward dependence, as introduced by Cloninger in a multicenter study (11 centers in the United Kingdom, Eire, Switzerland, and Austria) with detoxified alcohol-dependent patients (n = 521). The objective of this study was to evaluate a possible predictive value of these three dimensions on relapse over 1 -year follow up. A logistic regression analysis showed that novelty seeking is a strong predictor for relapse in detoxified male alcoholics (p = 0.0007; p values adjusted for treatment), but not in females. In both sexes, HA and reward dependence were of no predictive value. However, we found a trend for significance of HA for predicting "early" relapse (4 weeks) in females (p = 0.074). Our results show that Tridimensional Personality Questionnaire personality traits have direct clinical applications for prediction of relapse in detoxified alcohol dependents and indicate the necessity of additional therapeutic treatment in risk groups.
authors: Department of General Psychiatry, University Hospital for Psychiatry, Vienna, Austria.
authors: K
authors: K
authors: Meszaros
authors: E
authors: E
authors: Lenzinger
authors: K
authors: K
authors: Hornik
authors: T
authors: T
authors: Füreder
authors: U
authors: U
authors: Willinger
authors: G
authors: G
authors: Fischer
authors: G
authors: G
authors: Schönbeck
authors: H N
authors: HN
authors: Aschauer
mesh_terms: D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000523:psychology* / Q000628:therapy; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010551:Personality / Q000502:physiology*; D010552:Personality Assessment; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012008:Recurrence; D012044:Regression Analysis; D011795:Surveys and Questionnaires