Outbreaks of gastroenteritis caused by SRSVs from 1987 to 1992 in Kyushu, Japan: four outbreaks associated with oyster consumption.
From 1987 to 1992, 18 outbreaks of acute non-bacterial gastroenteritis occurred in Kyushu district. The most common symptoms were diarrhea, vomiting, nausea and abdominal cramp. Small round structured viruses (SRSVs) were detected in 52 (44.8%) of 116 stool samples from 17 outbreaks by the electron microscopy (EM) method, and a significant increase in the antibody level was noted in 42 (80.7%) of 52 paired serum samples from 12 outbreaks by the immune electron microscopy (IEM) method and in 18 (51.4%) of 35 samples from 8 outbreaks by the western blot (WB) method. However, according to the WB method, antigen-antibody reaction was not observed to reference antigen strips (SRSV-9/Tokyo 86-510, 63 kDa) in three of the 8 outbreaks. The detected virus was regarded as an etiologic agent for these outbreaks. In four of 5 outbreaks which appeared associated with eating raw oysters, there was a close relation between SRSV infection and consumption of raw oysters.
Otsu
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Fukuoka Institute of Health and Environmental Sciences, Dazaifu, Japan.
D000208:Acute Disease; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D000937:Antigen-Antibody Reactions; D015153:Blotting, Western; D017250:Caliciviridae Infections / Q000453:epidemiology*; D003085:Colic / Q000453:epidemiology / Q000821:virology; D003967:Diarrhea / Q000453:epidemiology / Q000821:virology; D004196:Disease Outbreaks; D005243:Feces / Q000821:virology; D005517:Foodborne Diseases / Q000453:epidemiology*; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008854:Microscopy, Electron; D016253:Microscopy, Immunoelectron; D009325:Nausea / Q000453:epidemiology / Q000821:virology; D009663:Norwalk virus / Q000276:immunology; D010125:Ostreidae / Q000821:virology; D014839:Vomiting / Q000453:epidemiology / Q000821:virology
D000914:Antibodies, Viral