title: Herpesvirus vaccines. Development, controversies, and applications.
abstract: Herpesviruses present difficult challenges in vaccine development because of their ability to evade immune clearance. Data and recommendations regarding the live-attenuated varicella vaccine are discussed. Approaches to developing vaccines to prevent herpes simplex virus (HSV), cytomegalovirus (CMV), and Epstein-Barr virus (EBV)-associated illnesses also are considered.
authors: Food and Drug Administration, Center for Biologics Evaluation and Research, Office of Vaccines Research and Review, Bethesda, Maryland, USA.
authors: P R
authors: PR
authors: Krause
authors: S E
authors: SE
authors: Straus
mesh_terms: D006564:Herpesviridae / Q000276:immunology*; D006566:Herpesviridae Infections / Q000145:classification / Q000517:prevention & control* / Q000821:virology*; D006801:Humans; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D014613:Vaccines, Attenuated; D014765:Viral Vaccines