Modifications of receptor concentrations for adrenaline, steroid hormones, prostaglandin F2alpha and gonadotropins in hypophysis and ovary of dairy cows with ovarian cysts.
Receptor concentrations for adrenaline, steroid hormones, PGF2alpha, LH and FSH were measured in the hypophysis and ovary of dairy cows with ovarian cysts and the results were compared with those of healthy animals. Significant modifications were found in all receptor concentrations, either between follicular and luteal structures or between the hypophyseal and ovarian receptorial status. The correlations between catecholaminergic and steroidal systems have already been demonstrated, particularly those existing between beta-adrenoceptors and steroid hormone receptors. Particular attention has been given to the possibility that a derangement in neurogenic inputs may be at the basis of some ovarian pathologies. The results of the present study suggest that the modifications of the ovarian and hypophyseal receptorial status of healthy and affected cows could play an important role in the pathogenesis of ovarian cysts.
Odore
R
R
Department of Animal Pathology, Division of Pharmacology and Toxicology, University of Turin, via Nizza 52, Turin, I-10126, Italy.
Re
G
G
Badino
P
P
Donn
A
A
Vigo
D
D
Biolatti
B
B
Girardi
C
C
D000818:Animals; D002417:Cattle; D004958:Estradiol / Q000097:blood; D005260:Female; D010048:Ovarian Cysts / Q000378:metabolism* / Q000473:pathology; D010053:Ovary / Q000166:cytology / Q000378:metabolism*; D010902:Pituitary Gland / Q000166:cytology / Q000378:metabolism*; D011374:Progesterone / Q000097:blood; D011943:Receptors, Adrenergic, beta / Q000378:metabolism; D011944:Receptors, Androgen / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism*; D011960:Receptors, Estrogen / Q000378:metabolism; D011962:Receptors, FSH / Q000378:metabolism; D011974:Receptors, LH / Q000378:metabolism; D011980:Receptors, Progesterone / Q000378:metabolism; D011982:Receptors, Prostaglandin / Q000378:metabolism
D011943:Receptors, Adrenergic, beta; D011944:Receptors, Androgen; D011956:Receptors, Cell Surface; D011960:Receptors, Estrogen; D011962:Receptors, FSH; D011974:Receptors, LH; D011980:Receptors, Progesterone; D011982:Receptors, Prostaglandin; C034671:prostaglandin F2alpha receptor; D011374:Progesterone; D004958:Estradiol