title: Histological study of periapical tissue healing in the rat molar after retrofilling with various materials.
abstract: We histologically examined the effects on the periapical tissue of various dental filling materials applied as retrofillings in rats and compared them with those of amalgam. The 4-META-TBB resin Superbond and the light-cured composite resin produced the least severe inflammatory reaction, with the greatest amount of new bone. In these specimens, regeneration of a part of the periodontal ligament was also observed. These results indicate that these materials might be very biocompatible and thus foster the natural regeneration of the periapical tissue.
authors: Department of Operative Dentistry and Endodontology, Faculty of Dentistry, Kyushu University, Fukuoka, Japan.
authors: H
authors: H
authors: Maeda
authors: I
authors: I
authors: Hashiguchi
authors: H
authors: H
authors: Nakamuta
authors: Y
authors: Y
authors: Toriya
authors: N
authors: N
authors: Wada
authors: A
authors: A
authors: Akamine
mesh_terms: D000818:Animals; D001047:Apicoectomy; D001672:Biocompatible Materials / Q000633:toxicity; D003723:Dental Amalgam / Q000633:toxicity; D005899:Glass Ionomer Cements / Q000633:toxicity; D008297:Male; D010486:Periapical Tissue / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012184:Retrograde Obturation; D012387:Root Canal Filling Materials / Q000633:toxicity*; D014945:Wound Healing / Q000187:drug effects*; D015035:Zinc Oxide-Eugenol Cement / Q000633:toxicity
chemical_list: D001672:Biocompatible Materials; D005899:Glass Ionomer Cements; D012387:Root Canal Filling Materials; D015035:Zinc Oxide-Eugenol Cement; D003723:Dental Amalgam