Basement membranes: Putting up the barriers.
The basement membrane is a highly organized extracellular matrix with adhesive and barrier functions. Assembly of this matrix uses two types of cell surface receptor, integrins and dystroglycan, to coordinate formation of a polygonal network of laminin, a major basement membrane protein.
Schwarzbauer
J
J
Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544-1014, USA. jschwarzbauer@molbio.princeton.edu
D000818:Animals; D001485:Basement Membrane / Q000502:physiology; D002462:Cell Membrane / Q000378:metabolism; D003598:Cytoskeletal Proteins / Q000378:metabolism; D049030:Dystroglycans; D005109:Extracellular Matrix / Q000502:physiology*; D006801:Humans; D016023:Integrins / Q000378:metabolism; D008562:Membrane Glycoproteins / Q000378:metabolism
D003598:Cytoskeletal Proteins; C483081:DAG1 protein, human; D016023:Integrins; D008562:Membrane Glycoproteins; D049030:Dystroglycans