Nausea and vomiting after laparoscopic gynecological surgery: a study of the incidence and the effects of tropisetron prophylaxis.
The authors studied the incidence of postoperative nausea and vomiting (PONV) and the effect of prophylactic tropisetron, a 5-HT3 antagonist, during the first 24 h following elective gynecologic laparoscopic surgery. Thirty-two of 68 (47%) of the patients experienced nausea or vomiting some time during the observation period. Sixteen of the 32 PONV patients (50%) had their first emetic symptoms after discharge from the recovery room. We could see no difference in the frequency of PONV in the patients who were given prophylactic tropisetron 5 mg orally before anesthesia.
Jakobsson
J
J
Department of Anaesthesia, Sabbatsberg Närsjukhuset, Sweden.
Dahlgren
G
G
Oddby
E
E
Ryberg
G
G
D000293:Adolescent; D000328:Adult; D000932:Antiemetics / Q000627:therapeutic use*; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects*; D006801:Humans; D007211:Indoles / Q000627:therapeutic use*; D010535:Laparoscopy / Q000009:adverse effects*; D008875:Middle Aged; D020250:Postoperative Nausea and Vomiting / Q000209:etiology / Q000517:prevention & control*; D000077526:Tropisetron
D000932:Antiemetics; D007211:Indoles; D000077526:Tropisetron