[The physiological role of nitric oxide].
The review is devoted to exposition of a physiological role of a nitric oxide (NO), free radical gas, in various physiological functions. The number of those NO involvements is extremely high: bacteriocidal, cytotoxic and antitumor leukocyte effects, a relaxation of smooth-muscle cells of both vessels and gastrointestinal tract, the name just a few. The scheme of NO formation in various biological systems and its targets were shown and neuromodulator functions of NO in a brain were analyzed by the review presented. The findings of own researches on a role of NO in function of neuro-muscular synapse were included by the authors.
Urazaev
A Kh
AKh
Kazan State Medical University.
Zefirov
A L
AL
D000818:Animals; D001921:Brain / Q000502:physiology; D004730:Endothelium, Vascular / Q000502:physiology; D004789:Enzyme Activation; D006801:Humans; D017774:Long-Term Potentiation / Q000502:physiology; D008264:Macrophages / Q000502:physiology; D009469:Neuromuscular Junction / Q000502:physiology; D009569:Nitric Oxide / Q000096:biosynthesis / Q000494:pharmacology / Q000502:physiology* / Q000633:toxicity; D019001:Nitric Oxide Synthase / Q000378:metabolism; D013569:Synapses / Q000502:physiology
D009569:Nitric Oxide; D019001:Nitric Oxide Synthase