Using amino-cerv after cervical LEEP.
OBJECTIVE
To evaluate the ability of Amino-Cerv to promote healing of the cervix following loop electrical excision procedure (LEEP) of the cervix for cervical intraepithelial neoplasia.


METHODS
A randomized study was conducted on 48 women in a private office setting. Patients were divided into two groups, to use or not use Amino-Cerv intravaginally for two weeks after the procedure. Statistical analysis of the findings were performed using the chi 2 test.


RESULTS
Twenty of 24 (83%) of women using Amino-Cerv had completely healed tissue at four weeks, whereas 12 of 24 (50%) in the untreated group had healed tissue at four weeks. Findings were not statistically significant at two weeks but were statistically significant (P < .005, power = .55) at four weeks after the procedure.


CONCLUSIONS
Amino-Cerv after LEEP of the cervix promotes healing.
Gimpelson
R J
RJ
Department of Obstetrics and Gynecology, St. Louis University School of Medicine, Missouri, USA.
Graham
B
B
D000282:Administration, Intravaginal; D004564:Electrocoagulation; D005260:Female; D006801:Humans; D007294:Inositol / Q000008:administration & dosage / Q000494:pharmacology*; D008715:Methionine / Q000008:administration & dosage / Q000494:pharmacology*; D011184:Postoperative Period; D013997:Time Factors; D016896:Treatment Outcome; D014508:Urea / Q000008:administration & dosage / Q000494:pharmacology*; D002583:Uterine Cervical Neoplasms / Q000601:surgery*; D014622:Vaginal Creams, Foams, and Jellies; D014945:Wound Healing / Q000187:drug effects*; D002578:Uterine Cervical Dysplasia / Q000601:surgery*
C119929:Amino-Cerv; D014622:Vaginal Creams, Foams, and Jellies; D007294:Inositol; D014508:Urea; D008715:Methionine