[Genetic monitoring of the population of the Carpathian region under anthropogenic pollution of the environment].
A genetic monitoring was conducted in a number of ecological regions of Precarpathia on the basis of clinical and epidemiological indices for the frequency of spontaneous abortions, specific weight of multiple birth, dynamics of number born living over the twelve-year period of 1985-1996, with the incidence and nosological spectrum of congenital malformations and hereditary diseases having been characterized. Negative genetic changes were disclosed in those communities under health-hazard conditions. Predominance of spontaneous abortions early in gestation was established together with decline in birth rate, increase in perinatal mortality, congenital malformations, and hereditary diseases in neonates and in children having died in the perinatal period.
Baryliak
I R
IR
Koval'chuk
L Ie
LIe
Kocherha
Z R
ZR
D000022:Abortion, Spontaneous / Q000453:epidemiology; D000013:Congenital Abnormalities / Q000453:epidemiology; D004781:Environmental Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data; D004787:Environmental Pollution / Q000009:adverse effects* / Q000706:statistics & numerical data; D005260:Female; D005313:Fetal Death / Q000453:epidemiology; D030342:Genetic Diseases, Inborn / Q000453:epidemiology; D005820:Genetic Testing; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D011247:Pregnancy; D011272:Pregnancy, Multiple / Q000706:statistics & numerical data; D012189:Retrospective Studies; D014455:Ukraine / Q000453:epidemiology