title: Chemical ligation to obtain proteins comprising helices with individual amino acid sequences.
abstract: Development of the strategies for assembling multiple kinds of peptide segments would give new possibilities for the de novo design of functional proteins. We will introduce our approach for the selective assembly of helical peptide segments on a peptide template to give four-helix-bundle proteins comprising individual helices.
authors: Institute for Medicinal Resources, The University of Tokushima, Japan. futaki@scl.kyoto-u.ac.jp
authors: S
authors: S
authors: Futaki
authors: M
authors: M
authors: Aoki
authors: T
authors: T
authors: Ishikawa
authors: F
authors: F
authors: Kondo
authors: T
authors: T
authors: Asahara
authors: M
authors: M
authors: Niwa
authors: Y
authors: Y
authors: Nakaya
authors: T
authors: T
authors: Yagami
authors: K
authors: K
authors: Kitagawa
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002942:Circular Dichroism; D004593:Electrophorus / Q000378:metabolism; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry*; D017433:Protein Structure, Secondary; D011506:Proteins / Q000138:chemical synthesis* / Q000737:chemistry; D015222:Sodium Channels / Q000737:chemistry
chemical_list: D010455:Peptides; D011506:Proteins; D015222:Sodium Channels