[Mathematical models in hemostasis physiology].
A mathematical model of spatial propagation of blood coagulation is proposed. The control mechanism of advancement of the activation zone is established. The intrinsic and extrinsic pathways of blood coagulation are considered. Blood flow transfer of the activated factors is shown to play a significant role in stopping advancement of the activation zone. This effect is amplified by the coagulation cascade. Propagation of the concentration wave is related to the model indices.
Barynin
Iu A
IuA
Russian State University of Technology, Moscow, Russia.
Starkov
I A
IA
Khanin
M A
MA
D000818:Animals; D001777:Blood Coagulation / Q000502:physiology; D006487:Hemostasis / Q000502:physiology*; D008297:Male; D008954:Models, Biological