[Deviations in the hematological indices of women exposed to aromatic hydrocarbons].
The indices of peripheral blood were investigated in 73 female laboratorians of the "Complex Laboratory for Analysis of Aromatic Carbohydrates", who were distributed into four groups according to the intensity of exposition. In the air of the laboratory medium the following substances were determined: benzene, toluen, xylols, ethylenic oxide, acrylnitril. The established concentrations were below or around the values of the mean maximum admissible concentrations (MMACV). Eleven indices of the three blood populations were followed up including white blood cell differential count and assessment of the activity of alkaline phosphatase in the polymorphonuclears. The same indices were investigated in 22 females, forming a control group. It was established that 26% of the examined female laboratorians were with anaemic syndrome, in 22.8% leucocytosis was present, while the alkaline phosphatase in the polymorphonuclears was with strongly inhibited activity. Although that on the bases of the formed 4 groups the dependencies "dose-response" and "dose-effect" were not established, the described deviations in the indices of the peripheral blood and expressed in a high percentage of the female laboratorians of the "Complex Laboratory for Analysis of Aromatic Carbohydrates" (CLAAC) direct to exerted effect by the occupational chemical harms upon the blood system of the examined females.
Khristeva-Mircheva
V
V
Traĭkova
E
E
D001769:Blood / Q000187:drug effects*; D001772:Blood Cell Count / Q000187:drug effects; D002031:Bulgaria; D005260:Female; D006801:Humans; D006841:Hydrocarbons, Aromatic / Q000009:adverse effects*; D007753:Laboratories; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis / Q000706:statistics & numerical data; D018709:Statistics, Nonparametric
D006841:Hydrocarbons, Aromatic