title: The cumulative incidence of atopic dermatitis in the first 12 months among Chinese, Vietnamese, and Caucasian infants born in Melbourne, Australia.
abstract: BACKGROUND
  Atopic dermatitis (AD), a disease with both inherited and environmental components determining its clinical expression, has been reported to be more frequent in people of Asian origin.
  
  
  OBJECTIVE
  Our purpose was to compare the 12-month cumulative incidence of AD in Caucasian, Chinese, and Vietnamese babies born in Australia.
  
  
  METHODS
  Sixty-two Caucasian, 61 Chinese, and 59 Vietnamese babies born in Melbourne, Australia were examined soon after birth and then followed up for 12 months to assess the frequency of AD. Parental education, employment history, and housing conditions were also recorded.
  
  
  RESULTS
  AD developed in 21% of Caucasians, 44% of Chinese, and 17% of Vietnamese infants. Parents of the Chinese and Caucasian infants had similar socioeconomic and housing conditions compared with the parents of the Vietnamese infants, who tended to be of lower socioeconomic status with communal housing and lack of plush-pile carpeting.
  
  
  CONCLUSIONS
  The high incidence of AD in Chinese compared with Caucasian infants tends to reflect genetic differences between the two populations, whereas the difference in incidence between the Chinese and Vietnamese infants possibly reflects more the environmental contribution to disease expression.
authors: The University of Melbourne, Department of Medicine (Dermatology), St Vincent's Hospital, Australia.
authors: A
authors: A
authors: Mar
authors: M
authors: M
authors: Tam
authors: D
authors: D
authors: Jolley
authors: R
authors: R
authors: Marks
mesh_terms: D002681:China / Q000208:ethnology; D003431:Cross-Cultural Comparison; D003430:Cross-Sectional Studies; D003876:Dermatitis, Atopic / Q000453:epidemiology / Q000208:ethnology* / Q000235:genetics; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006798:Housing; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012959:Socioeconomic Factors; D014739:Victoria; D014744:Vietnam / Q000208:ethnology; D044465:White People