title: Effect of cooled intraocular irrigating solution on the blood-aqueous barrier after cataract surgery.
abstract: OBJECTIVE
  To evaluate the effect of cooled intraocular irrigating solution during phacoemulsification on postoperative blood-aqueous barrier (BAB) disturbance.
  
  
  METHODS
  Department of Ophthalmology, University of Vienna, Austria.
  
  
  METHODS
  In a prospective, randomized clinical study, 40 eyes with senile cataract had phacoemulsification with irrigating solutions cooled to approximately 10 degrees C (n = 20) or at room temperature (n = 20). Surgical procedure and postoperative therapy were otherwise identical in both groups. Postoperative BAB disturbance was assessed with the laser flare-cell meter on days 1, 3, 7, 14, and 28.
  
  
  RESULTS
  Anterior chamber flare was significantly lower in the group with cooled irrigating solution on postoperative day 1. There was no significant between-group difference in flare on any other postoperative day.
  
  
  CONCLUSIONS
  Cooled intraocular irrigating solution reduced immediate postoperative inflammation compared with irrigating solution at room temperature. However, this effect was of short duration.
authors: Department of Ophthalmology, University of Vienna, Austria.
authors: O
authors: O
authors: Findl
authors: M
authors: M
authors: Amon
authors: A
authors: A
authors: Kruger
authors: V
authors: V
authors: Petternel
authors: J
authors: J
authors: Schauersberger
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000473:pathology; D018916:Blood-Aqueous Barrier; D002452:Cell Count; D003080:Cold Temperature; D017679:Cryotherapy; D004338:Drug Combinations; D004837:Epinephrine / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D005839:Gentamicins / Q000008:administration & dosage; D006801:Humans; D007552:Isotonic Solutions / Q000008:administration & dosage*; D017078:Laser-Doppler Flowmetry; D008297:Male; D018918:Phacoemulsification; D011446:Prospective Studies; D000077331:Ringer's Solution; D007507:Therapeutic Irrigation; D014606:Uveitis, Anterior / Q000473:pathology / Q000517:prevention & control*
chemical_list: D004338:Drug Combinations; D005839:Gentamicins; D007552:Isotonic Solutions; D000077331:Ringer's Solution; D004837:Epinephrine