United Kingdom Prospective Diabetes Study (UKPDS). Effects of glucose and blood pressure control on complications of type 2 diabetes mellitus.
The United Kingdom Prospective Diabetes Study (UKPDS) showed that intensive treatment (i.e., glucose-lowering drugs, with a goal fasting blood glucose level of 108 mg/dL) decreases the microvascular complications of type 2 diabetes mellitus. We summarize the key study results and their implications for clinical management of type 2 diabetes mellitus.
Nasr
C E
CE
Department of Endocrinology and Metabolism, Cleveland Clinic, USA.
Hoogwerf
B J
BJ
Faiman
C
C
Reddy
S S
SS
D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000378:metabolism / Q000517:prevention & control*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000517:prevention & control*; D008875:Middle Aged; D009765:Obesity / Q000150:complications* / Q000517:prevention & control*; D018579:Patient Selection; D011446:Prospective Studies; D016896:Treatment Outcome; D006113:United Kingdom
D001786:Blood Glucose