Carcinoid heart disease and carcinoid syndrome: successful surgical treatment.
Tumor debulking can greatly improve quality of life for patients with malignant carcinoid syndrome, but hepatic cytoreduction is confounded by carcinoid heart disease, which can cause postsinusoidal portal hypertension, thereby increasing the risk of death from hemorrhage during hepatic resection. We describe a patient with metastatic carcinoid syndrome and carcinoid heart disease who had repair of his carcinoid heart disease and, after improvement of right-sided heart function, had successful hepatic debulking of carcinoid metastases.
McDonald
M L
ML
Division of Gastroenterologic and General Surgery, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.
Nagorney
D M
DM
Connolly
H M
HM
Nishimura
R A
RA
Schaff
H V
HV
D000328:Adult; D001705:Bioprosthesis; D002275:Carcinoid Heart Disease / Q000175:diagnosis / Q000601:surgery*; D002276:Carcinoid Tumor / Q000556:secondary* / Q000601:surgery; D006349:Heart Valve Diseases / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery; D008297:Male; D008303:Malignant Carcinoid Syndrome / Q000175:diagnosis / Q000601:surgery*; D011788:Quality of Life; D012086:Reoperation