Revising the selfish DNA hypothesis: new evidence on accumulation of transposable elements in heterochromatin.
The bulk of the eukaryotic genome is composed of families of repetitive sequences that are genetically silent and exhibit various types of instability. Transposable elements (TEs) are particularly common in heterochromatic regions of the genome - a location where TEs might do less damage to their host. Recent advances suggest that the relationship between TEs and heterochromatin might not be quite so straightforward.
Dimitri
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Dipartimento di Genetica e Biologia Molecolare, Università 'La Sapienza', Piazzale A. Moro, 00185 Roma, Italy. dmitri@axcasp.caspur.it
Junakovic
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D000818:Animals; D002843:Chromatin / Q000235:genetics; D004251:DNA Transposable Elements / Q000235:genetics*; D022041:Euchromatin; D006570:Heterochromatin / Q000235:genetics*; D006801:Humans; D008957:Models, Genetic
D002843:Chromatin; D004251:DNA Transposable Elements; D022041:Euchromatin; D006570:Heterochromatin