Spontaneous remission of chiasmatic/hypothalamic masses in neurofibromatosis type 1: report of two cases.
We report two children with neurofibromatosis type 1 showing enhancing masses on MRI suggesting neoplasms in the chiasm and hypothalamic region. In both patients no visual or endocrinal dysfunction was present. On serial MRI spontaneous partial remission was found, implying that a cautious approach to therapeutic management of similar cases should be taken.
Gottschalk
S
S
Department of Neuroradiology, Charité, Humboldt University of Berlin, Germany.
Tavakolian
R
R
Buske
A
A
Tinschert
S
S
Lehmann
R
R
D001254:Astrocytoma / Q000473:pathology*; D002675:Child, Preschool; D003390:Cranial Nerve Neoplasms / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D007029:Hypothalamic Neoplasms / Q000473:pathology*; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009365:Neoplasm Regression, Spontaneous; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000473:pathology; D009897:Optic Chiasm / Q000473:pathology*