title: Measles in adults in Canada and the United States: implications for measles elimination and eradication.
abstract: BACKGROUND
  Despite the implementation of mass school catch-up campaigns for measles in Canada, an outbreak of measles occurred in early 1997 mostly affecting the adult population. The higher incidence in Canada in adults led us to compare immunization policies and the evolution of measles among adults in Canada and the US.
  
  
  METHODS
  Based on information gathered from both national immunization programmes and surveillance systems.
  
  
  RESULTS
  Although the proportion of cases occurring in adults has increased tremendously in both countries in the past decade, there was no increase in measles incidence in these populations. The most likely factors to explain the higher rate of measles occurring in adults in Canada are the younger age at administration of first dose in Canada, the delay in implementation of a second dose policy in Canada compared with the US combined with the lack of prematriculation immunization requirements in Canadian colleges and universities, and the higher rate of overseas travel to and from Canada. The situation in Canada may also have been exacerbated by incomplete efforts to control measles for many years without attempting to eliminate the disease.
  
  
  CONCLUSIONS
  In order to prevent measles in adults, high-risk groups must be identified and catch-up for selected groups considered. Vaccination of international travellers to endemic areas should be recommended until global elimination has been achieved. Appropriate measles control strategies in younger populations seem to be effective in preventing measles in adults. The experience in Canada and the US suggests that measles transmission in adults is unlikely to be a major impediment to regional elimination or global eradication.
authors: Division of Immunization, Bureau of Infectious Diseases, Laboratory Centre for Disease Control, Ottawa, Ontario, Canada.
authors: P
authors: P
authors: Duclos
authors: S C
authors: SC
authors: Redd
authors: P
authors: P
authors: Varughese
authors: B S
authors: BS
authors: Hersh
mesh_terms: D000328:Adult; D002170:Canada / Q000453:epidemiology; D004196:Disease Outbreaks / Q000517:prevention & control*; D006801:Humans; D017589:Immunization Programs / Q000458:organization & administration*; D015994:Incidence; D008457:Measles / Q000453:epidemiology / Q000517:prevention & control*; D014481:United States / Q000453:epidemiology