title: Analgesic, antiinflammatory and hypoglycaemic activities of Sida cordifolia.
abstract: Sida cordifolia extracts of the aerial and root parts showed good analgesic, antiinflammatory and hypoglycaemic activities. The ethyl acetate (EA) extract of root (SCR-E) showed comparable antiinflammatory activity with indomethacin and possessed significantly higher activity when compared with that of the methanol extract of the root part (SCR-M). The ethyl acetate extract of both root and aerial parts of Sida cordifolia (SCR-E and SCA-E) showed very good central and peripheral analgesic activities at a dose of 600 mg/kg. The methanol extract of root (SCR-M) was found to possess significant hypoglycaemic activity.
authors: Pharmacology Division, Indian Institute of Chemical Technology, Hyderabad, India.
authors: V R
authors: VR
authors: Kanth
authors: P V
authors: PV
authors: Diwan
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D001786:Blood Glucose / Q000378:metabolism; D002351:Carrageenan; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D007194:India; D008297:Male; D051379:Mice; D010147:Pain Measurement / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D011930:Reaction Time / Q000187:drug effects
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D002351:Carrageenan