Diagnosis and treatment of gastric motility disorders.
A disorder of gastric motility should be suspected in patients with chronic vomiting. Imaging studies are used to confirm delayed gastric emptying, the most common form of a gastric motility disorder. Other causes of chronic vomiting, for example, metabolic or endocrine disorders, other abdominal disorders, mechanical causes of gastric obstruction, and lower gastrointestinal tract disease, are then ruled out. If no underlying cause is determined, a functional disorder of gastric emptying is presumptively diagnosed. Treatment consists of dietary management and gastric prokinetic agents. Cisapride is the drug of choice for treating delayed gastric emptying followed by erythromycin and ranitidine or nizatidine.
Hall
J A
JA
Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, USA. hallje@ccmail.orst.edu
Washabau
R J
RJ
D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis / Q000188:drug therapy*; D002415:Cats; D020117:Cisapride / Q000494:pharmacology / Q000627:therapeutic use; D004283:Dog Diseases / Q000175:diagnosis / Q000188:drug therapy*; D004285:Dogs; D004917:Erythromycin / Q000494:pharmacology / Q000627:therapeutic use; D005746:Gastric Emptying / Q000187:drug effects; D005765:Gastrointestinal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D008787:Metoclopramide / Q000494:pharmacology / Q000627:therapeutic use; D016567:Nizatidine / Q000494:pharmacology / Q000627:therapeutic use; D011899:Ranitidine / Q000494:pharmacology / Q000627:therapeutic use; D013272:Stomach Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*
D005765:Gastrointestinal Agents; D004917:Erythromycin; D011899:Ranitidine; D008787:Metoclopramide; D016567:Nizatidine; D020117:Cisapride