Herpesvirus vaccines. Development, controversies, and applications.
Herpesviruses present difficult challenges in vaccine development because of their ability to evade immune clearance. Data and recommendations regarding the live-attenuated varicella vaccine are discussed. Approaches to developing vaccines to prevent herpes simplex virus (HSV), cytomegalovirus (CMV), and Epstein-Barr virus (EBV)-associated illnesses also are considered.
Krause
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PR
Food and Drug Administration, Center for Biologics Evaluation and Research, Office of Vaccines Research and Review, Bethesda, Maryland, USA.
Straus
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D006564:Herpesviridae / Q000276:immunology*; D006566:Herpesviridae Infections / Q000145:classification / Q000517:prevention & control* / Q000821:virology*; D006801:Humans; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*
D014613:Vaccines, Attenuated; D014765:Viral Vaccines