title: [Comparative study of various methods for determining Vibrio cholerae toxigenicity].
abstract: Testing of 138 Vibrio cholerae strains for gene determinants responsible for the production of cholera enterotoxin by the polymerase chain reaction (PCR) and gene probing using molecular CT-probe showed good correlation of the results of different methods and correlation of these data with studies of V. cholerae strain virulence in vivo and in hemolytic activity test. The advantages of PCR in rapid assessment of the toxigenicity and epidemic significance of V. cholerae strains are demonstrated.
authors: S V
authors: SV
authors: Balakhonov
authors: V S
authors: VS
authors: Ganin
authors: L Ia
authors: LIa
authors: Urbanovich
authors: V I
authors: VI
authors: Pogorelov
authors: E P
authors: EP
authors: Golubinskiĭ
mesh_terms: D015342:DNA Probes; D004768:Enterotoxins / Q000096:biosynthesis* / Q000633:toxicity; D006461:Hemolysis / Q000187:drug effects; D016133:Polymerase Chain Reaction; D014734:Vibrio cholerae / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity*
chemical_list: D015342:DNA Probes; D004768:Enterotoxins; C037420:stN protein, Vibrio cholerae