Abbreviated aerosol therapy for improved efficiency.
BACKGROUND
The Circulaire nebulizer system (WestMed, Tucson, AZ) has been shown to minimize the potential for side effects from adrenergic bronchodilator aerosols by minimizing extrapulmonary deposition. This study evaluates the utility, safety, and efficacy of a shortened treatment protocol utilizing a timed treatment with concentrated drug in this device.


METHODS
Prospective, randomized, controlled comparison was conducted of a 2-minute treatment of concentrated (5 mg/mL) albuterol in the Circulaire nebulizer versus a conventional unit dose treatment as assessed by pulmonary function testing.


RESULTS
Both treatments were equally efficacious and safe. The abbreviated treatment consumed about 8 to 10 minutes less and was preferred by patients.


CONCLUSIONS
Abbreviated treatments provide equal bronchodilation with improved efficiency and potential cost savings.
Mason
J W
JW
Pulmonary Center, Columbia Clear Lake Regional Medical Center, Webster, Texas, USA.
Miller
W C
WC
D001993:Bronchodilator Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000188:drug therapy / Q000503:physiopathology; D009330:Nebulizers and Vaporizers; D011446:Prospective Studies; D012129:Respiratory Function Tests
D001993:Bronchodilator Agents