Poliomyelitis-like syndrome associated with Epstein-Barr virus infection.
A 20-month-old male presented with an acute clinical syndrome resembling poliomyelitis, characterized by a flaccid monoplegia, areflexia of the involved limb, and preserved sensation. Electrophysiologic studies supported a neuronopathic localization involving the anterior horn cells. Although laboratory evidence for a poliovirus infection was absent, serologic and polymerase chain reaction studies documented an active central nervous system infection with Epstein-Barr virus, indicating that a poliomyelitis-like syndrome may be produced by infectious agents other than enteroviruses.
Wong
M
M
Department of Neurology, Washington University School of Medicine, St. Louis Children's Hospital, Missouri.
Connolly
A M
AM
Noetzel
M J
MJ
D003937:Diagnosis, Differential; D004576:Electromyography; D020031:Epstein-Barr Virus Infections / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009188:Myelitis, Transverse / Q000209:etiology; D010264:Paraplegia / Q000209:etiology; D011051:Poliomyelitis / Q000175:diagnosis*; D016896:Treatment Outcome