Determination of salbutamol and detection of other beta-agonists in human postmortem whole blood and urine by GC-MS-SIM.
This paper details a sensitive and quantitative method for the determination of salbutamol and the detection of terbutaline, clenbuterol, fenoterol, and isoprenaline in postmortem human whole blood and urine. It describes solid-phase extraction using a XtrackT XRDAH515 column, formation of trimethylsilyl derivatives, and analysis by gas chromatography-mass spectrometry-selective ion monitoring.
Black
S B
SB
Forensic Science Laboratory, Chemistry Centre (WA), East Perth, Western Australia, Australia.
Hansson
R C
RC
D000318:Adrenergic beta-Agonists / Q000097:blood / Q000378:metabolism* / Q000652:urine; D000420:Albuterol / Q000097:blood* / Q000652:urine*; D001344:Autopsy; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006801:Humans; D066298:In Vitro Techniques; D017736:Ion-Selective Electrodes; D012680:Sensitivity and Specificity
D000318:Adrenergic beta-Agonists; D000420:Albuterol