[An amino acid metabolic complex in optimizing the cardiac hemodynamic characteristics of patients with ischemic heart disease].
On the basis of findings from examination of 82 patients with ischemic heart disease presenting with exertional angina, functional class II-III, aged 62-86 years, efficacy was studied of an amino acid metabolic complex consisting of glutamic acid and methionine combined with basic antianginal drugs and single basic therapy with nitrates and calcium antagonists. Criteria for efficacy were condition of central cardiohemodynamics and inotropic indices. Glutamic acid and methionine combined with basic agents were found to make for enhancement of contractile function of ischemized myocardium, with the left ventricular local contractility being improved against the background of reduction in postload.
Berezin
A E
AE
Fushteĭ
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IM
Kraĭdashenko
O V
OV
D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000188:drug therapy / Q000503:physiopathology; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D018698:Glutamic Acid / Q000627:therapeutic use*; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008715:Methionine / Q000627:therapeutic use*; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000188:drug therapy* / Q000503:physiopathology; D005082:Physical Exertion; D013997:Time Factors
D004338:Drug Combinations; D018698:Glutamic Acid; D008715:Methionine