title: Polychlorinated dibenzo-p-dioxins and related compounds in breast milk of Japanese primiparas and multiparas.
abstract: We analyzed polychlorinated dibenzo-p-dioxins and related compounds in the breast milk of primiparas and multiparas, and estimated the levels transferred to newborns by breast milk in Western Japan. 2,3,7,8-TeCDD equivalents (TEQ) of the chemicals in primiparas decreased slightly from 1994 to 1996. In particular, decreases of the TEQs of total PCDDs and total coplanar PCBs were higher than that of total PCDFs. In 2,3,7,8-TeCDD, 1,2,3,7,8-PeCDD, 1,2,3,6,7,8-HxCDD, 1,2,3,7,8,9-HxCDD, 2,3,4,7,8-PeCDF, 1,2,3,6,7,8-HxCDF, 3,3',4,4',5-PeCB and 3,3',4,4',5,5'-HxCB concentrations, those in the breast milk of multiparas were significantly lower than those in the breast milk of primiparas (p < 0.05, lipid basis). Based on the assumption that newborns ingest 120 g of breast milk per kg body weight per day, the amounts converted to TEQ values were 121 pg/kg/day (primiparas) and 97.2 pg/kg/day (multiparas).
authors: Fukuoka Institute of Health & Environmental Sciences, Japan.
authors: T
authors: T
authors: Iida
authors: H
authors: H
authors: Hirakawa
authors: T
authors: T
authors: Matsueda
authors: S
authors: S
authors: Takenaka
authors: J
authors: J
authors: Nagayama
mesh_terms: D000328:Adult; D004785:Environmental Pollutants / Q000032:analysis*; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007564:Japan; D008297:Male; D008895:Milk, Human / Q000737:chemistry*; D010298:Parity; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000032:analysis; D013997:Time Factors
chemical_list: D004785:Environmental Pollutants; D000072317:Polychlorinated Dibenzodioxins