CA 125 in benign gynecological conditions.
The tumor marker CA 125 was initially thought to be specific for ovarian malignancies. Subsequently it was found to be raised in a variety of benign conditions, including pregnancy, pelvic inflammatory disease, tuberculosis and cirrhosis of the liver. With respect to gynecological tumors, CA 125 may be elevated in benign ovarian cysts, tubo-ovarian abscess, endometriosis, hyperstimulation syndrome, ectopic pregnancy and fibroids. These results demonstrate that CA 125 is a marker of non-specific peritoneal conditions.
Meden
H
H
Department of Obstetrics and Gynecology, University of Göttingen, Germany.
Fattahi-Meibodi
A
A
D014408:Biomarkers, Tumor / Q000097:blood; D018394:CA-125 Antigen / Q000097:blood*; D004715:Endometriosis / Q000097:blood; D005260:Female; D005831:Genital Diseases, Female / Q000097:blood* / Q000175:diagnosis*; D006801:Humans; D008598:Menstruation / Q000097:blood; D010051:Ovarian Neoplasms / Q000097:blood / Q000175:diagnosis*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000097:blood / Q000175:diagnosis; D012680:Sensitivity and Specificity
D014408:Biomarkers, Tumor; D018394:CA-125 Antigen