title: Massive pleural effusion and ascites resulting from esophagectomy with extensive lymphadenectomy for cancer of the abdominal esophagus.
abstract: Chylothorax is an uncommon but well recognized complication of esophagectomy. We present the case of a 57 year-old man with squamous cell carcinoma of the abdominal esophagus who underwent subtotal esophagectomy by right thoracotomy. Post-operatively, the volume of pleural effusion from the right chest was increased (1600-2000 ml/day). The effusion was straw colored, not changing to milky after meals. The characteristics and composition of the pleural fluid were similar to those of chyle. We therefore treated this patient using methods for treatment of chylothorax, conservatively, by administration of OK-432 and minocycline/hydrochloride into the pleural cavity from the chest tube with success. We discuss the pathophysiology of this unusual condition and its treatment.
authors.affiliation: Second Department of Surgery, Hyogo College of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: K
authors.initials: K
authors.lastname: Nakagawa
authors.forename: M
authors.initials: M
authors.lastname: Kusunoki
authors.forename: T
authors.initials: T
authors.lastname: Hatada
authors.forename: T
authors.initials: T
authors.lastname: Yamamura
authors.forename: J
authors.initials: J
authors.lastname: Utsunomiya
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001201:Ascites / Q000209:etiology*; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D004938:Esophageal Neoplasms / Q000601:surgery*; D016629:Esophagectomy / Q000009:adverse effects*; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D008911:Minocycline / Q000627:therapeutic use; D010844:Picibanil / Q000627:therapeutic use; D010996:Pleural Effusion / Q000209:etiology* / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D010844:Picibanil; D008911:Minocycline