title: Persistent crying as predominant manifestation of sepsis in infants and newborns.
abstract: Acute episodes of unexplained crying in infants may be due to serious and even life-threatening conditions. We present six infants in whom excessive crying was the predominant initial manifestation of sepsis for a period of time that ranged from 2 to 10 hours, before other symptoms or signs became evident. This led to a diagnostic delay in two patients who were considered initially to have infant colic. Sepsis should be considered in the differential diagnosis of acute unexplained crying in infants.
authors.affiliation: Departamento de Pediatría, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Ruiz-Contreras
authors.forename: L
authors.initials: L
authors.lastname: Urquía
authors.forename: R
authors.initials: R
authors.lastname: Bastero
mesh_terms: D003085:Colic / Q000175:diagnosis; D003448:Crying; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D018805:Sepsis / Q000175:diagnosis* / Q000382:microbiology / Q000503:physiopathology*; D013290:Streptococcal Infections / Q000175:diagnosis / Q000382:microbiology; D013292:Streptococcus agalactiae; D013997:Time Factors