Rapid screening for organochlorine and organophosphorus pesticides in milk using C18 and graphitized carbon black solid phase extraction cleanup.
A rapid, multiresidue, solid phase extraction (SPE) technique for the isolation and gas chromatographic determination of organochlorine and moderately polar organophosphorus pesticide residues in milk is described. Milk is sonicated with an acetonitrile-acetone-methanol mixture and centrifuged. The supernatant is subjected to a cleanup using both C18 and graphitized carbon black SPE columns. The pesticide residues are determined by gas chromatography with electron capture and flame photometric detection. The method required minimal volumes of solvent and resulted in the production of minimal volumes of hazardous waste.
Schenck
F J
FJ
U.S. Food and Drug Administration, Baltimore District Laboratory, MD 21201, USA.
Casanova
J
J
D000818:Animals; D002244:Carbon / Q000032:analysis; D002849:Chromatography, Gas; D004784:Environmental Monitoring; D005506:Food Contamination; D006843:Hydrocarbons, Chlorinated; D007306:Insecticides / Q000032:analysis*; D008892:Milk / Q000737:chemistry*; D009943:Organophosphorus Compounds; D012822:Silicon Dioxide / Q000032:analysis; D012995:Solubility; D013997:Time Factors
D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D009943:Organophosphorus Compounds; C026679:octadecylsilica; D002244:Carbon; D012822:Silicon Dioxide