title: Wuchereria bancrofti antigenaemia in Sri Lanka.
abstract: The prevalence of Wuchereria bancrofti antigenaemia determined in 353 subjects in Matara, Sri Lanka by Og4C3 ELISA was 20.7%. Positive rates obtained with the same subjects by 1 ml Nuclepore filtration and 60 microl thick blood smear were 11.3% and 7.9%, respectively. Antigen levels were positively associated with microfilaria counts. Two-thirds of antigen-positive and microfilaria-negative (Ag+/Mf-) individuals were > 25-year-old, but younger age groups (< or = 25-year-old) tended to have proportionally more Ag+/Mf- cases. Possible origins of the Ag+/Mf- status are discussed.
authors.affiliation: Department of Parasitology, Aichi Medical University, Aichi-ken, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Itoh
authors.forename: M V
authors.initials: MV
authors.lastname: Weerasooriya
authors.forename: N K
authors.initials: NK
authors.lastname: Gunawardena
authors.forename: M P
authors.initials: MP
authors.lastname: Mudalige
authors.forename: W A
authors.initials: WA
authors.lastname: Samarawickrema
authors.forename: E
authors.initials: E
authors.lastname: Kimura
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000947:Antigens, Helminth / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005368:Filariasis / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D016036:Seroepidemiologic Studies; D013188:Sri Lanka / Q000453:epidemiology; D014958:Wuchereria bancrofti / Q000276:immunology* / Q000302:isolation & purification
chemical_list: D000947:Antigens, Helminth