A new antiviral and antimicrobial sesquiterpene from Glyptopetalum sclerocarpum.
Sclerocarpic acid, a new sesquiterpene with a novel carbon skeleton, was isolated from the stem bark of Glyptopetalum sclerocarpum Laws. (Celastraceae). The compound exhibited antiviral activity against herpes simplex virus types 1 and 2, and antimicrobial activity against Gram-positive bacteria and a fungus.
Sotanaphun
U
U
Lipipun
V
V
Suttisri
R
R
Bavovada
R
R
D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D033364:Decapoda / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D018259:Herpesvirus 1, Human / Q000187:drug effects; D018258:Herpesvirus 2, Human / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000998:Antiviral Agents; D012717:Sesquiterpenes; C119280:sclerocarpic acid