Changes in platelet demand in association with the spread of autologous peripheral blood progenitor cell transplantation.
Changes in platelet demand accompanying widespread application of autologous peripheral blood progenitor cell transplantation (APBPCT) were anticipated. The differences in the transfused volume of platelet concentrate (PC) among 8 patients with malignant lymphoma who were treated with APBPCT and 10 patients with malignant lymphoma who were not treated with APBPCT, although peripheral blood progenitor cell harvests had been performed, were studied. The former was 81 Japanese PC units more than the latter. Considering the supplied volume of PC from Red Cross blood centers and the number of APBPCTs in 1996 in Japan, the Japanese demand for PC increases by 0.16% for enforced APBPCT versus 0.36%, which includes the PC demand necessary in all treatment courses. The total increment in PC demand associated with APBPCT is not large enough to threaten the PC supply of Japan even if the number of APBPCTs increases rapidly.
Ueda
Y
Y
Transfusion and Haemapheresis Center and Department of Internal Medicine, Kurashiki Central Hospital, Japan.
Ikeda
Y
Y
Watanabe
S
S
Kitawaki
T
T
Matsuyama
F
F
Konishi
H
H
Yagiri
Y
Y
D000328:Adult; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000706:statistics & numerical data*; D006801:Humans; D007564:Japan; D007937:Leukapheresis; D008228:Lymphoma, Non-Hodgkin / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D017713:Platelet Transfusion / Q000706:statistics & numerical data*; D014182:Transplantation, Autologous