Isolated renal Aspergillus abscess in an AIDS patient with a normal CD4+ cell count on highly active antiretroviral therapy.
Isolated renal Aspergillus abscess is a very rare complication of HIV infection. It usually occurs in patients with severe immune deficiency. The case of a 29-year-old HIV-infected homosexual male, a nonintravenous drug abuser, who developed a right renal Aspergillus abscess despite normalization of the CD4+ cell count after highly active antiretroviral treatment is described. When antimicrobial treatment failed (amphotericin B followed by itraconazole), he was cured by right nephrectomy and remains in good health 3 months later with no recurrence. In cases of Aspergillus renal abscess in HIV-infected patients, surgery is the treatment of choice, especially in the current era of highly active antiretroviral therapy.
Rey
D
D
Centre d'Informations et de Soins de l'Immunodéficience Humaine, Clinique Médicale A, Hôpitaux Universitaires, Strasbourg, France. david.rey@chru-strasbourg.fr
de Mautort
E
E
Saussine
C
C
Hansmann
Y
Y
Waller
J
J
Herbrecht
R
R
Christmann
D
D
Lindner
V
V
Letscher-Bru
V
V
Koenig
H
H
Lang
J M
JM
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology* / Q000601:surgery; D000038:Abscess / Q000382:microbiology* / Q000601:surgery; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000382:microbiology*; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D018791:CD4 Lymphocyte Count; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007674:Kidney Diseases / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D008297:Male
D019380:Anti-HIV Agents