[Valacyclovir].
The paper concerns the new antiviral compound Valaciclovir--prodrug of Aciclovir, which is now in clinical studies. Antiviral activity, pharmacokinetic properties observed in animal studies, as well in immunocompetent and immunosuppressed patients are presented. Its clinical efficacy in herpes virus infection is also discussed.
Biernat-Sudolska
M
M
Zakładu Wirusologii, Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.
D000212:Acyclovir / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use*; D006566:Herpesviridae Infections / Q000188:drug therapy*; D006801:Humans; D000077483:Valacyclovir; D014633:Valine / Q000031:analogs & derivatives* / Q000627:therapeutic use
D000998:Antiviral Agents; D014633:Valine; D000077483:Valacyclovir; D000212:Acyclovir