title: The use of an inhomogeneous applied field improves the spatial sensitivity profile of an in vivo SQUID susceptometer.
abstract: We present a SQUID susceptometer with a non-homogeneous magnetizing field which is null at the sensing coil and increases towards the patient position with a constant gradient plus a cubic term at large distances. Compared with the magnetizing fields of similar instruments described in the literature, our gradient field enhances the signal due to internal organs with respect to the signal due to superficial tissue. Preliminary measurements have been performed on phantoms of known magnetic susceptibility. The advantage of using a non-homogeneous field compared with a uniform field has been investigated in the case of a double-layer phantom.
authors.affiliation: Istituto di Tecnologie Avanzate Biomediche, Università Gabriele D'Annunzio, Chieti, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Della Penna
authors.forename: C
authors.initials: C
authors.lastname: Del Gratta
authors.forename: S
authors.initials: S
authors.lastname: Di Luzio
authors.forename: V
authors.initials: V
authors.lastname: Pizzella
authors.forename: K
authors.initials: K
authors.lastname: Torquati
authors.forename: G L
authors.initials: GL
authors.lastname: Romani
mesh_terms: D004578:Electron Spin Resonance Spectroscopy / Q000295:instrumentation / Q000379:methods; D006801:Humans; D007501:Iron / Q000032:analysis; D008099:Liver / Q000737:chemistry; D008280:Magnetics; D019047:Phantoms, Imaging
chemical_list: D007501:Iron