Bacterial invasion: Force feeding by Salmonella.
Recent findings have shed new light on mammalian-cell invasion by Salmonella. Using a type III secretion system, Salmonella deliver virulence factors into the host cell that directly activate signal transduction pathways, initiating cytoskeletal rearrangements and bacterial uptake by a ruffling mechanism.
Brumell
J H
JH
Biotechnology Laboratory, University of British Columbia, Vancouver, Canada.
Steele-Mortimer
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O
Finlay
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BB
D000818:Animals; D001424:Bacterial Infections / Q000378:metabolism / Q000503:physiopathology*; D001426:Bacterial Proteins / Q000378:metabolism; D012481:Salmonella Infections, Animal / Q000378:metabolism / Q000503:physiopathology; D012486:Salmonella typhimurium / Q000254:growth & development / Q000472:pathogenicity; D015398:Signal Transduction
D001426:Bacterial Proteins