Nephrotic syndrome, microcephaly, and developmental delay: three separate syndromes.
We describe a patient with microcephaly, developmental delay, and nephrotic syndrome who had normal renal function and normal brain imaging studies. She does not have the Galloway-Mowat syndrome. The concurrence of nephrotic syndrome with microcephaly and developmental delay may be coincidental, or may reflect one of at least three syndromes: Galloway-Mowat, a second syndrome of microcephaly, nephrotic syndrome and developmental delay (MNSDD), and a third syndrome of microcephaly, developmental delay, and spondylorhizomelic short stature.
Meyers
K E
KE
Division of Nephrology, Children's Hospital of Philadelphia and the University of Pennsylvania 19104, USA.
Kaplan
P
P
Kaplan
B S
BS
D002658:Developmental Disabilities / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D008831:Microcephaly / Q000150:complications*; D009404:Nephrotic Syndrome / Q000150:complications*; D013577:Syndrome