title: [The MR tomographic imaging of uncomplicated secondary fracture healing exemplified by the distal radius fracture].
abstract: OBJECTIVE
  To investigate the normal sequential MR-pattern of uncomplicated fracture healing within the first 6 weeks.
  
  
  METHODS
  In 8 patients with distal radius fracture, 4 by 4 with and without intraarticular fracture, MR examinations were performed 3-4 days after the onset of fracture and after 1, 2, 3, 4, 5 and 6 weeks using the following techniques: T1-weighted spin echo, T2-weighted spin echo, T2 proton density weighted, STIR (short inversion time inversion recovery), T2-weighted turbo spin-echo and fast field echo (FFE, gradient echo). Sequential examinations were analysed regarding 1) the appearance of fracture line, 2) development of bone marrow signal, and 3) signal changes in surrounding soft tissue. Maximum contrast of bone marrow and soft tissue was measured.
  
  
  RESULTS
  The fracture line in bone marrow was best detectable in FFE- and T2-weighted spin ech images during the first week and in T2-weighted fast spin echo and proton density-weighted images from the 2nd to 4th week. Beginning in the 5th-6th week an increase of signal intensity in the fracture gap was typical in all sequences except for T1-weighted spin echo. The contrast maximum of bone marrow and soft tissue, best detectable in STIR- and T2-weighted spin echo images, occurred in the 1st-2nd week.
  
  
  CONCLUSIONS
  MRI shows a typical time-depending pattern of the fracture line, surrounding bone marrow and soft tissue in normal fracture healing. The degree of injury influences the development of signal changes.
authors.affiliation: Institut und Poliklinik für Radiologische Diagnostik, Universität Köln. Karsten.Krueger@Uni-Koeln.de
authors.forename: K
authors.initials: K
authors.lastname: Krüger
authors.forename: W
authors.initials: W
authors.lastname: Heindel
authors.forename: C
authors.initials: C
authors.lastname: Burger
authors.forename: H G
authors.initials: HG
authors.lastname: Brochhagen
authors.forename: A
authors.initials: A
authors.lastname: Prokop
authors.forename: K
authors.initials: K
authors.lastname: Lackner
mesh_terms: D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D017102:Fracture Healing; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011859:Radiography; D011884:Radius / Q000000981:diagnostic imaging / Q000473:pathology; D011885:Radius Fractures / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D013997:Time Factors