title: [Evolutive visceral malaria and hyperimmune palustral splenomegaly: a difficult distinction].
abstract: One case of hyperreactive malarial splenomegaly is reported for a Comores Island patient living in France and having thus lost his protective immunity. Plasmodium falciparum was detected in a bone marrow aspiration, whereas peripheral venous blood samples were negative. A three-month treatment of sulfadoxine + pyrimethamine was effective with a complete regression of splenomegaly and biological disorders.
authors.affiliation: Laboratoire de parasitologie, Hôpital Saint Louis, Paris.
authors.forename: J P
authors.initials: JP
authors.lastname: Gangneux
authors.forename: S
authors.initials: S
authors.lastname: Vignes
authors.forename: Y
authors.initials: Y
authors.lastname: Poinsignon
authors.forename: F
authors.initials: F
authors.lastname: Derouin
mesh_terms: D000328:Adult; D000818:Animals; D001853:Bone Marrow / Q000469:parasitology; D017507:Comoros / Q000208:ethnology; D003937:Diagnosis, Differential; D005602:France; D006801:Humans; D016778:Malaria, Falciparum / Q000175:diagnosis* / Q000276:immunology* / Q000469:parasitology; D008297:Male; D010963:Plasmodium falciparum / Q000302:isolation & purification; D013163:Splenomegaly / Q000276:immunology* / Q000469:parasitology