title: Study on the direct electron transfer process of superoxide dismutase.
abstract: The electron transfer process of biological important species, superoxide dismutase (SOD), was studied using cyclic voltammetric method at different conditions. The rate of electron transfer process of SOD at conventional bare gold electrode was very low. Different methods were used to enhance the rate of this process. Gold microdisk electrode and gold minigrid electrode were used to replace the used conventional size gold electrode and the electron transfer rate was enhanced obviously. Different promoters, such as bis(4-pyridyl)disulfide, histidine and arginine, were used to promote the electron transfer process also. Promising results were observed with the help of those promoters. The rate enhancement through the participation of amino acids might be more interesting for the exploration of the real process of SOD-related reaction inside the human body.
authors.affiliation: Department of Chemistry, Shanghai Teachers University, China. xqwu@shtu.edu.cn
authors.forename: X Q
authors.initials: XQ
authors.lastname: Wu
authors.forename: X Y
authors.initials: XY
authors.lastname: Meng
authors.forename: Z S
authors.initials: ZS
authors.lastname: Wang
authors.forename: Z R
authors.initials: ZR
authors.lastname: Zhang
mesh_terms: D001120:Arginine / Q000737:chemistry; D004220:Disulfides / Q000737:chemistry; D004563:Electrochemistry; D004566:Electrodes; D004579:Electron Transport; D006639:Histidine / Q000737:chemistry; D006801:Humans; D011725:Pyridines / Q000737:chemistry; D013482:Superoxide Dismutase / Q000737:chemistry*
chemical_list: D004220:Disulfides; D011725:Pyridines; C007542:4,4'-dipyridyl disulfide; D006639:Histidine; D001120:Arginine; D013482:Superoxide Dismutase