title: A new antiviral and antimicrobial sesquiterpene from Glyptopetalum sclerocarpum.
abstract: Sclerocarpic acid, a new sesquiterpene with a novel carbon skeleton, was isolated from the stem bark of Glyptopetalum sclerocarpum Laws. (Celastraceae). The compound exhibited antiviral activity against herpes simplex virus types 1 and 2, and antimicrobial activity against Gram-positive bacteria and a fungus.
authors.forename: U
authors.initials: U
authors.lastname: Sotanaphun
authors.forename: V
authors.initials: V
authors.lastname: Lipipun
authors.forename: R
authors.initials: R
authors.lastname: Suttisri
authors.forename: R
authors.initials: R
authors.lastname: Bavovada
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D033364:Decapoda / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D018259:Herpesvirus 1, Human / Q000187:drug effects; D018258:Herpesvirus 2, Human / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000998:Antiviral Agents; D012717:Sesquiterpenes; C119280:sclerocarpic acid