title: Granular cell tumor of the breast: report of a case.
abstract: A case of granular cell tumor of the breast in a 43-year-old woman is described. The patient presented with a painless mass in the upper-outer quadrant of her right breast. Mammography showed a spiculated tumor and ultrasonography demonstrated a hypoechoic mass with an irregular border. Magnetic resonance (MR) mammography revealed a homogeneous enhanced mass in T1-weighted images using Gd-DTPA and a ringed high-intensity area around the mass in T2-weighted images. Fine-needle aspiration cytology failed to show any malignant cells. A partial resection of the breast was performed and histological examination revealed a granular cell tumor. Granular cell tumors are generally always benign, but they may be misdiagnosed as malignant tumors because of their mammographic and ultrasonographic findings. MR mammography did not reveal a typical breast cancer in either T1- or T2-weighted images in the present case. This case illustrates the need for care in preoperative examinations in order to avoid overdiagnosis of breast cancer.
authors.affiliation: Second Department of Surgery, Hiroshima University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kohashi
authors.forename: T
authors.initials: T
authors.lastname: Kataoka
authors.forename: R
authors.initials: R
authors.lastname: Haruta
authors.forename: K
authors.initials: K
authors.lastname: Sugino
authors.forename: S
authors.initials: S
authors.lastname: Marubayashi
authors.forename: H
authors.initials: H
authors.lastname: Yahata
authors.forename: T
authors.initials: T
authors.lastname: Asahara
authors.forename: S
authors.initials: S
authors.lastname: Fujii
authors.forename: K
authors.initials: K
authors.lastname: Arihiro
authors.forename: K
authors.initials: K
authors.lastname: Dohi
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D016586:Granular Cell Tumor / Q000473:pathology*; D006801:Humans