title: Calcification in mucinous cholangiocellular carcinoma.
abstract: Calcification is rarely seen in cholangiocellular carcinoma. We herein report the case of a 53 year-old man with calcification in a cholangiocellular carcinoma. Because imaging studies had revealed coarse calcified foci, hepatolithiasis was suspected pre-operatively. The patient underwent a laparotomy in which intra-operative cholangioscopy revealed no gallstones but did reveal an unsuspected tumor with abundant mucin. A left hepatic lobectomy with resection of the extrahepatic bile duct was performed. The tumor histology was mucinous adenocarcinoma with calcification. In the English language literature, we found 9 cases of cholangiocellular carcinoma with macroscopic calcification. Six of these cases were mucinous adenocarcinomas. Roentgenologic examination revealed coarse calcification in 7 cases and fine calcification in 2 cases. Clinicians should note that cholangiocellular carcinoma, especially the mucinous variant, may be accompanied by coarse calcification.
authors.affiliation: Department of Surgery, Niigata University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Nagakura
authors.forename: Y
authors.initials: Y
authors.lastname: Shirai
authors.forename: K
authors.initials: K
authors.lastname: Yamai
authors.forename: K
authors.initials: K
authors.lastname: Hatakeyama
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D002114:Calcinosis / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed