title: Konjac mannan improves the vitamin B-6 status of rats fed a vitamin B-6-deficient diet.
abstract: To investigate how dietary fiber in the diet affects vitamin B-6 nutriture of rats which have been deprived of vitamin B-6, rats were made vitamin B-6-deficient by feeding a vitamin B-6-deficient 70% casein diet. They were fed 2% cellulose powder-based vitamin B-6-deficient diets supplemented with 3% of additional dietary fiber sources (agar, konjac mannan, pectin and cellulose powder) for subsequent 18 days. Vitamin B-6 status was evaluated according to several biological criteria (weight gain, urinary excretion of xanthurenic acid after tryptophan loading, plasma pyridoxal 5'-phosphate, apparent pyridoxal 5'-phosphate-saturation of liver kynureninase, urinary excretion of 4-pyridoxic acid and fecal output of vitamin B-6). Vitamin B-6 status evaluated by these criteria was considerably improved in the konjac mannan-fed group, when compared with the respective data of the vitamin B-6 supplemented group. The relative mean effect of the konjac mannan diet was about 40% of the vitamin B-6 supplemented diet. In conclusion, konjac mannan was effective for improving the vitamin B-6 nutritional state in vitamin B-6-deprived rats.
authors.affiliation: Department of Food Science, Faculty of Agriculture, Gifu University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hayakawa
authors.forename: Y
authors.initials: Y
authors.lastname: Iida
authors.forename: H
authors.initials: H
authors.lastname: Tsuge
mesh_terms: D000818:Animals; D004043:Dietary Fiber / Q000494:pharmacology*; D002149:Energy Intake; D005243:Feces / Q000737:chemistry; D006867:Hydrolases / Q000378:metabolism; D008297:Male; D008351:Mannans / Q000494:pharmacology*; D011735:Pyridoxic Acid / Q000652:urine; D011736:Pyridoxine / Q000097:blood* / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D026681:Vitamin B 6 Deficiency / Q000097:blood*; D015430:Weight Gain; D014977:Xanthurenates / Q000652:urine
chemical_list: D004043:Dietary Fiber; D008351:Mannans; D014977:Xanthurenates; C022901:(1-6)-alpha-glucomannan; C028330:xanthurenic acid; D011735:Pyridoxic Acid; D006867:Hydrolases; C021480:kynureninase; D011736:Pyridoxine