Potent estrogenic agonists bearing dicarba-closo-dodecaborane as a hydrophobic pharmacophore.
Endo
Y
Y
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Iijima
T
T
Yamakoshi
Y
Y
Yamaguchi
M
M
Fukasawa
H
H
Shudo
K
K
D000818:Animals; D001880:Boranes / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D019556:COS Cells; D047628:Estrogen Receptor alpha; D004967:Estrogens / Q000819:agonists* / Q000378:metabolism; D006801:Humans; D051381:Rats; D011960:Receptors, Estrogen / Q000819:agonists / Q000096:biosynthesis; D013329:Structure-Activity Relationship; D014162:Transfection
D001880:Boranes; D047628:Estrogen Receptor alpha; D004967:Estrogens; D011960:Receptors, Estrogen