Anticonvulsant hypersensitivity syndrome occurring as sepsis with multiorgan dysfunction.
Phenytoin is a highly effective and widely prescribed anticonvulsant agent. However, it is associated with both dose-related side effects and hypersensitivity reactions. Life-threatening anticonvulsant hypersensitivity syndrome in one patient was characterized by a skin eruption and multisystem organ dysfunction.
Marik
P
P
Department of Medicine, Washington Hospital Center, DC, USA.
D000927:Anticonvulsants / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000139:chemically induced*; D010672:Phenytoin / Q000009:adverse effects*; D018805:Sepsis / Q000139:chemically induced*; D013577:Syndrome
D000927:Anticonvulsants; D010672:Phenytoin