Application of neural networks in structure-activity relationships.
Methodology and application of artificial neural networks in structure-activity relationships are reviewed focusing on the most frequently used three-layer feedforward back-propagation procedure. Two applications of neural networks are presented and a comparison of the performance with those of CoMFA and a classical QSAR analysis is also discussed.
Kövesdi
I
I
EGIS Pharmaceuticals Ltd., Budapest, Hungary.
Dominguez-Rodriguez
M F
MF
Orfi
L
L
Náray-Szabó
G
G
Varró
A
A
Papp
J G
JG
Mátyus
P
P
D015195:Drug Design; D016571:Neural Networks, Computer; D013329:Structure-Activity Relationship