title: Assessment of dry weight in hemodialysis: an overview.
abstract: Fluid balance is an integral component of hemodialysis treatments to prevent under- or overhydration, both of which have been demonstrated to have significant effects on intradialytic morbidity and long-term cardiovascular complications. Fluid removal is usually achieved by ultrafiltration to achieve a clinically derived value for "dry weight." Unfortunately, there is no standard measure of dry weight and as a consequence it is difficult to ascertain adequacy of fluid removal for an individual patient. Additionally, there is a lack of information on the effect of ultrafiltration on fluid shifts in the extracellular and intracellular fluid spaces. It is evident that a better understanding of both interdialytic fluid status and fluid changes during hemodialysis is required to develop a precise measure of fluid balance. This article describes the current status of dry weight estimation and reviews emerging techniques for evaluation of fluid shifts. Additionally, it explores the need for a marker of adequacy for fluid removal.
authors.affiliation: Department of Medicine, University of California, San Diego, USA.
authors.forename: J Q
authors.initials: JQ
authors.lastname: Jaeger
authors.forename: R L
authors.initials: RL
authors.lastname: Mehta
mesh_terms: D015415:Biomarkers; D001810:Blood Volume / Q000502:physiology; D001826:Body Fluids / Q000378:metabolism*; D001835:Body Weight / Q000502:physiology; D006331:Heart Diseases / Q000209:etiology / Q000401:mortality; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000401:mortality; D006435:Renal Dialysis / Q000009:adverse effects / Q000592:standards*
chemical_list: D015415:Biomarkers