title: [The development of malignant tumors in nevus sebaceus--therapeutic consequences].
abstract: OBJECTIVE
  Nevus sebaceus has been considered a relatively infrequent and unimportant congenital hamartoma for plastic surgeons, unless the lesions are so big that they require a large closure of the defect. As such tumors are primarily of a benign nature and the malformed sebaceus glands are located abnormally high in the dermis, surgeons are tempted not to excise the tumors but to eradicate them by dermabrasion or laser beam therapy. Yet, a nevus sebaceus does not only affect sebaceus glands but includes various other malformations of the affected skin and its appendages. In addition, different malignant tumors may occur in nevus sebaceus, even in children and young adults.
  
  
  METHODS
  We encountered 4 such malignant tumors out of 18 nevus sebaceus operated from 1989 to 1997. All nevi had been clinically inconspicuous.
  
  
  RESULTS
  In three patients, one of them being only fifteen years old, an associated basal cell carcinoma was found. The fourth patient had a mixture of three additional tumours, a cystadenoma, a keratoacanthoma and a basal cell carcinoma besides the sebaceous malformations.
  
  
  CONCLUSIONS
  These findings have two consequences. The first is to continue surgical treatment of nevus sebaceus instead of dermabrasion or dermablation and to have the specimen examined histologically. The second consequence is to excise such tumors as early as possible.
authors.affiliation: Department für Wiederherstellungschirurgie, Universität Zürich, Schweiz. gertrude.beer@chi.usz.ch
authors.forename: G M
authors.initials: GM
authors.lastname: Beer
authors.forename: W
authors.initials: W
authors.lastname: Widder
authors.forename: K A
authors.initials: KA
authors.lastname: Cierpka
authors.forename: P
authors.initials: P
authors.lastname: Kompatscher
authors.forename: V E
authors.initials: VE
authors.lastname: Meyer
mesh_terms: D000293:Adolescent; D000328:Adult; D002280:Basal Cell Carcinoma / Q000601:surgery; D002648:Child; D003537:Cystadenoma / Q000601:surgery; D005153:Facial Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007636:Keratoacanthoma / Q000601:surgery; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000601:surgery; D009506:Nevus / Q000473:pathology* / Q000601:surgery*; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery*