title: Simultaneous involvement of the jejunum and the colon by type-1 neurofibromatosis.
abstract: Type-1 neurofibromatosis (NF-1) or Von Recklinghausen disease is an autosomal dominant hereditary condition that may affect the gastrointestinal tract in 25% of cases and which takes three main forms: ganglioneuromatosis, stromal tumors, and tumors in the duodenum and periampullar region. Not infrequently, these patients present with gastrointestinal bleeding. We present the case of a 48-year-old patient diagnosed as having NF-1, with relapsing episodes of gastrointestinal hemorrhage, in which we discovered the simultaneous presence of a stromal tumor in the jejunum together with polypoid and diffuse ganglioneuromatosis in the colon.
authors.affiliation: Dept. of Gastroenterology, Virgen de la Salud Hospital, Toledo, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Artaza
authors.forename: J F
authors.initials: JF
authors.lastname: García
authors.forename: C
authors.initials: C
authors.lastname: González
authors.forename: M
authors.initials: M
authors.lastname: Amengual
authors.forename: A
authors.initials: A
authors.lastname: Mazarro
authors.forename: R
authors.initials: R
authors.lastname: Rodríguez
authors.forename: J J
authors.initials: JJ
authors.lastname: Sánchez
mesh_terms: D003106:Colon / Q000473:pathology; D003110:Colonic Neoplasms / Q000150:complications / Q000473:pathology*; D005729:Ganglioneuroma / Q000150:complications / Q000473:pathology; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D007580:Jejunal Neoplasms / Q000150:complications / Q000473:pathology*; D007583:Jejunum / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications / Q000473:pathology*