title: Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IkappaB alpha/NF-kappaB pathway in limb-girdle muscular dystrophy type 2A.
authors.affiliation: Laboratoire de Dynamique Moléculaire des Interactions Membranaires, CNRS-UMR 5539, Université Montpellier II, France.
authors.forename: S
authors.initials: S
authors.lastname: Baghdiguian
authors.forename: M
authors.initials: M
authors.lastname: Martin
authors.forename: I
authors.initials: I
authors.lastname: Richard
authors.forename: F
authors.initials: F
authors.lastname: Pons
authors.forename: C
authors.initials: C
authors.lastname: Astier
authors.forename: N
authors.initials: N
authors.lastname: Bourg
authors.forename: R T
authors.initials: RT
authors.lastname: Hay
authors.forename: R
authors.initials: R
authors.lastname: Chemaly
authors.forename: G
authors.initials: G
authors.lastname: Halaby
authors.forename: J
authors.initials: J
authors.lastname: Loiselet
authors.forename: L V
authors.initials: LV
authors.lastname: Anderson
authors.forename: A
authors.initials: A
authors.lastname: Lopez de Munain
authors.forename: M
authors.initials: M
authors.lastname: Fardeau
authors.forename: P
authors.initials: P
authors.lastname: Mangeat
authors.forename: J S
authors.initials: JS
authors.lastname: Beckmann
authors.forename: G
authors.initials: G
authors.lastname: Lefranc
mesh_terms: D000293:Adolescent; D000328:Adult; D017209:Apoptosis; D001692:Biological Transport; D002154:Calpain / Q000172:deficiency* / Q000378:metabolism; D002451:Cell Compartmentation; D002467:Cell Nucleus / Q000473:pathology*; D002648:Child; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D005260:Female; D005333:Fetus; D005455:Fluorescent Antibody Technique; D006801:Humans; D020672:I-kappa B Proteins; D008297:Male; D018613:Microscopy, Confocal; D018482:Muscle, Skeletal / Q000378:metabolism / Q000473:pathology; D009136:Muscular Dystrophies / Q000145:classification / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D000072000:NF-KappaB Inhibitor alpha; D016328:NF-kappa B / Q000037:antagonists & inhibitors / Q000378:metabolism*; D011994:Recombinant Proteins / Q000378:metabolism
chemical_list: D004268:DNA-Binding Proteins; D020672:I-kappa B Proteins; D016328:NF-kappa B; C000606204:NFKBIA protein, human; D011994:Recombinant Proteins; D000072000:NF-KappaB Inhibitor alpha; D002154:Calpain