[The mechanisms of the neuroprotective action of carbonate mineral baths in ischemic brain lesions].
Effects of Arzni effervescent mineral baths (EMB) on brain tissue metabolism were studied on white rats (normal controls and those with transitory cerebral ischemia). It was found that EMB prevent ischemia-related disorders of phospholipid and adeninnucleotide pools, promote an increase in vasoactive prostaglandins in brain tissue, shifts in catecholamines concentrations in the hemispheres and hypothalamus, inhibit the activity of monoaminoxidase and absorption of 3H-noradrenaline by brains sections. Mechanisms of neuroprotective action of Arzni EMB in cerebral ischemia are considered.
Tunian
Iu S
IuS
Sekoian
E S
ES
Karagezian
K G
KG
Grigorian
R A
RA
Manucharian
G G
GG
Karagian
A T
AT
D000227:Adenine Nucleotides / Q000032:analysis / Q000378:metabolism; D000241:Adenosine / Q000032:analysis / Q000378:metabolism; D000818:Animals; D001136:Armenia; D001494:Baths / Q000379:methods*; D001921:Brain / Q000378:metabolism; D001923:Brain Chemistry; D002545:Brain Ischemia / Q000378:metabolism / Q000534:rehabilitation*; D002254:Carbonates / Q000627:therapeutic use*; D004195:Disease Models, Animal; D006294:Health Resorts; D008297:Male; D010743:Phospholipids / Q000032:analysis / Q000378:metabolism; D011453:Prostaglandins / Q000032:analysis / Q000378:metabolism; D051381:Rats
D000227:Adenine Nucleotides; D002254:Carbonates; D010743:Phospholipids; D011453:Prostaglandins; D000241:Adenosine