title: A new esterase gene amplification involved in OP resistance in Culex pipiens mosquitoes from China.
abstract: Two overproduced esterases (A8 and B8) not previously described were found in southern China. They provide a low resistance level to organophosphate (OP) insecticides, and correspond to a coamplification of both esterase loci (Est-2 and Est-3) classically involved in OP resistance for this mosquito species. This coamplification is distinct from all other similar events thus far reported. The peculiar situation in southern China, where numerous OP resistance alleles at these two loci were found, is discussed in comparison with the Mediterranean situation, the only one with a similar diversity of overproduced esterases.
authors.affiliation: Institute of Zoology, Academia Sinica, Beijing, China.
authors.forename: C L
authors.initials: CL
authors.lastname: Qiao
authors.forename: M
authors.initials: M
authors.lastname: Marquine
authors.forename: N
authors.initials: N
authors.lastname: Pasteur
authors.forename: M
authors.initials: M
authors.lastname: Raymond
mesh_terms: D000818:Animals; D003465:Culex / Q000201:enzymology / Q000235:genetics*; D004950:Esterases / Q000235:genetics*; D005784:Gene Amplification; D007305:Insecticide Resistance / Q000235:genetics*; D007306:Insecticides; D009943:Organophosphorus Compounds
chemical_list: D007306:Insecticides; D009943:Organophosphorus Compounds; D004950:Esterases