[Effectiveness of synthetic antioxidants in treatment of patients with peptic ulcer (an open randomized controlled trial)].
Two randomized groups of ulcer patients were compared. 102 patients of group 1 were treated with synthetic antioxidants (dibunol, probucol, emoxipine), while 100 patients of group 2 received a conventional treatment. Treatment results in group 1 appeared better: shortening of ulcer scarring, higher percentage of ulcer healing for 2 and 4 weeks, fall in the number of relapses during the first year of the follow-up, improvement in lipid peroxidation and antioxidant activity.
Podoprigorova
V G
VG
Khibin
L S
LS
Kozlov
N B
NB
Barsel'
V A
VA
D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use*; D002084:Butylated Hydroxytoluene / Q000627:therapeutic use*; D004381:Duodenal Ulcer / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism; D016145:Endoscopy, Digestive System; D005500:Follow-Up Studies; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008875:Middle Aged; D010847:Picolines / Q000627:therapeutic use*; D011341:Probucol / Q000627:therapeutic use*; D013276:Stomach Ulcer / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism; D016896:Treatment Outcome
D000975:Antioxidants; D010847:Picolines; D002084:Butylated Hydroxytoluene; D011341:Probucol; C009820:6-methyl-2-ethyl-3-hydroxypyridine