Neurocutaneous melanosis presenting with intracranial amelanotic melanoma.
We describe imaging findings in a 2-year-old girl with neurocutaneous melanosis and malignant cerebral melanoma. Because the cerebral melanoma in this child was of the amelanotic type, high-signal intensity on unenhanced T1-weighted images was not present. The cutaneous lesions played a crucial role in establishing a correct (presumed) histopathologic diagnosis on the basis of the imaging findings. To our knowledge this is the first report describing an intracranial amelanotic malignant melanoma in association with neurocutaneous melanosis.
Vanzieleghem
B D
BD
Department of Radiology, University Hospital Gent, Belgium.
Lemmerling
M M
MM
Van Coster
R N
RN
D001932:Brain Neoplasms / Q000473:pathology*; D003287:Contrast Media; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement; D007223:Infant; D008279:Magnetic Resonance Imaging; D018328:Melanoma, Amelanotic / Q000473:pathology*; D008548:Melanosis / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009508:Nevus, Pigmented / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*
D003287:Contrast Media; D019786:Gadolinium DTPA