Red cell apheresis: new concepts of blood component processing.
Since red cell apheresis procedures were introduced in Europe, more than 6,000 automated blood component collections have been processed. Analyzed were results of different protocols (RBCPS, RBCP, SDP-RBC). Quality of blood components was measured over a storage period of 42 days (red cell concentrates) versus 5 days (platelet concentrates). Processing times were <8 min for RBCPS, <22 min for RBCP, and <90 min for SDP-RBC. All collected blood components fit the standards of the European guidelines. The results for red cell concentrate storage are as good as the results for manual collection (ATP, hemolysis parameters, glucose, lactose) or better (2,3-DPG, rheological parameters). Storage data of platelet concentrates are similar to platelet apheresis. All apheresed blood products are sterile after storage. Red cell apheresis procedures are a challenge for blood component processing and will encourage a revision of national blood and plasma programs for self-sufficiency.
Matthes
G A
GA
D001782:Blood Donors; D001793:Blood Preservation; D016238:Cytapheresis / Q000379:methods* / Q000706:statistics & numerical data; D017707:Erythrocyte Transfusion; D004912:Erythrocytes / Q000502:physiology; D006801:Humans; D013997:Time Factors