On the front of X-linked adrenoleukodystrophy.
The profound and lasting involvement of Hugo and Ann Moser have allowed to make remarkable progress in adrenoleulodystrophy (ALD) during the last 20 years. Besides their own commitment in ALD, Hugo and Ann have constantly encouraged physicians, biologists and molecular geneticists to undertake clinical and fundamental research in this devastating disease. There is now some preventive and therapeutic approaches which can be proposed to ALD patients and families. The issues that still remain unresolved will certainly keep busy those who share the "Hugo and Ann spirit".
Aubourg
P
P
Université René Descartes, Institut National de la Santé et de la Recherche médicale (U342), Hôpital St Vincent de Paul, Paris, France. paubourg@cochin.inserm.fr
D000074063:ATP Binding Cassette Transporter, Subfamily D, Member 1; D018528:ATP-Binding Cassette Transporters / Q000235:genetics / Q000502:physiology; D000326:Adrenoleukodystrophy / Q000235:genetics*; D000818:Animals; D003711:Demyelinating Diseases / Q000235:genetics; D005787:Gene Frequency; D008040:Genetic Linkage / Q000235:genetics; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics / Q000502:physiology; D009154:Mutation / Q000502:physiology; D010641:Phenotype; D014960:X Chromosome / Q000235:genetics*
C115572:ABCD1 protein, human; D000074063:ATP Binding Cassette Transporter, Subfamily D, Member 1; D018528:ATP-Binding Cassette Transporters; D008565:Membrane Proteins