title: Plasma exchange for thrombocytopenia in antiphospholipid syndrome: a case report.
abstract: The remarkable effect of plasma exchange (PE) was observed on thrombocytopenia in a patient with antiphospholipid syndrome (APS) associated with systemic lupus erythematosus. Three times PE led to recovery from severe thrombocytopenia refractory to treatment with corticosteroid, anticoagulant, and antiplatelet drugs accompanied by a decrease in the serum cardiolipin beta2 glycoprotein I antibody level. This result suggests that PE is a valuable therapeutic tool for refractory thrombocytopenia in APS.
authors.affiliation: Department of Internal Medicine, Showa University Fujigaoka Hospital, Yokohama, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Satomi
authors.forename: F
authors.initials: F
authors.lastname: Koiwa
authors.forename: H
authors.initials: H
authors.lastname: Ogata
authors.forename: E
authors.initials: E
authors.lastname: Kinugasa
authors.forename: T
authors.initials: T
authors.lastname: Akizawa
authors.forename: T
authors.initials: T
authors.lastname: Ideura
mesh_terms: D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008297:Male; D010951:Plasma Exchange; D013921:Thrombocytopenia / Q000209:etiology* / Q000628:therapy*