title: The successful containment of coxsackie B4 infection in a neonatal unit.
abstract: This report describes the containment of a potential enterovirus epidemic in a neonatal intensive care unit. A case of neonatal enterovirus meningitis and myocarditis was identified. Polymerase chain reaction (PCR) was used to assist in appropriate cohorting of contacts. One further infant became cross-infected with Coxsackie B4. Serum PCR was accurate in detecting the infection in the early stages in this asymptomatic neonate. Neonatal enterovirus infection is relatively rare but has the potential to cause outbreaks in neonatal wards. PCR can be used to diagnose and monitor for cross infection.
authors.affiliation: Department of Neonatal Medicine, National Women's Hospital, Epsom, New Zealand.
authors.forename: B J
authors.initials: BJ
authors.lastname: Austin
authors.forename: M C
authors.initials: MC
authors.lastname: Croxson
authors.forename: K F
authors.initials: KF
authors.lastname: Powell
authors.forename: T R
authors.initials: TR
authors.lastname: Gunn
mesh_terms: D003384:Coxsackievirus Infections / Q000175:diagnosis / Q000517:prevention & control* / Q000821:virology; D003428:Cross Infection / Q000175:diagnosis / Q000517:prevention & control* / Q000821:virology; D004279:DNA, Viral / Q000032:analysis; D004196:Disease Outbreaks / Q000517:prevention & control*; D029822:Enterovirus B, Human / Q000235:genetics; D006801:Humans; D007231:Infant, Newborn; D017053:Infection Control / Q000379:methods*; D007363:Intensive Care Units, Neonatal; D008297:Male; D008587:Meningitis, Viral / Q000175:diagnosis / Q000517:prevention & control* / Q000821:virology; D009205:Myocarditis / Q000175:diagnosis / Q000517:prevention & control* / Q000821:virology; D016133:Polymerase Chain Reaction
chemical_list: D004279:DNA, Viral