Testicular fibroma of gonadal stromal origin with minor sex cord elements: clinicopathologic and immunohistochemical study of 2 cases.
OBJECTIVE
To report the histologic and immunohistochemical features of 2 cases of intratesticular fibromatous tumors.


RESULTS
Microscopically, these tumors were composed of short, randomly interweaving fascicles of spindle cells dispersed within a fibrocollagenous stroma. A sex cord component was detected in one case by microscopic examination and in both cases by immunohistochemical study using MIC2 and anti-inhibin antibodies.


CONCLUSIONS
The presence of minor sex cord elements, morphologically or by immunohistochemistry, suggests that these fibromatous tumors are related to and are a subset of sex cord-stromal tumors. Intratesticular fibromatous tumors, of which 11 other cases lacking sex cord elements have been reported, could be considered as the testicular equivalent of ovarian fibroma. These tumors could then be referred to as testicular fibroma of gonadal stromal origin, with or without minor sex cord component.
de Pinieux
G
G
Service d'anatomie pathologique, Hôpital Cochin, Paris, France.
Glaser
C
C
Chatelain
D
D
Perie
G
G
Flam
T
T
Vieillefond
A
A
D000293:Adolescent; D000328:Adult; D005350:Fibroma / Q000473:pathology; D006801:Humans; D008297:Male; D018312:Sex Cord-Gonadal Stromal Tumors / Q000473:pathology*; D013736:Testicular Neoplasms / Q000473:pathology*