title: Cardiovascular disease and treatment outcomes with osseointegration surgery.
abstract: BACKGROUND
  The frequency of prescription of implant-supported prostheses demands increased scrutiny of systemic health condition on treatment inclusion and exclusion criteria. The risks of an impaired healing response in patients with certain types of cardiovascular diseases (CVD) suggest a possible risk for implant failure in such patients.
  
  
  OBJECTIVE
  This preliminary study surveyed implant treatment outcome of patients with cardiovascular diseases.
  
  
  METHODS
  A retrospective analysis of 246 consecutively treated patients was conducted. The patients comprised a CVD interest group of 39 patients, and control subgroups of 98 healthy and 109 patients with a history of other systemic disease.
  
  
  RESULTS
  Differences in implant failure rates between the groups were not found to be significant. Though the sample size is small, these results suggest that CVD may not be a risk factor for successful osseointegration.
authors.affiliation: Faculty of Dentistry, University of Toronto, Ontario, Canada.
authors.forename: V
authors.initials: V
authors.lastname: Khadivi
authors.forename: J
authors.initials: J
authors.lastname: Anderson
authors.forename: G A
authors.initials: GA
authors.lastname: Zarb
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000150:complications*; D016009:Chi-Square Distribution; D003758:Dental Implantation, Endosseous / Q000009:adverse effects / Q000379:methods; D019232:Dental Restoration Failure; D004194:Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016348:Osseointegration; D018579:Patient Selection; D012189:Retrospective Studies; D012307:Risk Factors; D018401:Sample Size; D016896:Treatment Outcome; D014945:Wound Healing