Plasma exchange for thrombocytopenia in antiphospholipid syndrome: a case report.
The remarkable effect of plasma exchange (PE) was observed on thrombocytopenia in a patient with antiphospholipid syndrome (APS) associated with systemic lupus erythematosus. Three times PE led to recovery from severe thrombocytopenia refractory to treatment with corticosteroid, anticoagulant, and antiplatelet drugs accompanied by a decrease in the serum cardiolipin beta2 glycoprotein I antibody level. This result suggests that PE is a valuable therapeutic tool for refractory thrombocytopenia in APS.
Satomi
A
A
Department of Internal Medicine, Showa University Fujigaoka Hospital, Yokohama, Japan.
Koiwa
F
F
Ogata
H
H
Kinugasa
E
E
Akizawa
T
T
Ideura
T
T
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008297:Male; D010951:Plasma Exchange; D013921:Thrombocytopenia / Q000209:etiology* / Q000628:therapy*