Risperidone and clozapine combination for the treatment of refractory schizophrenia.
Clozapine is the most widely used antipsychotic drug for the treatment of refractory schizophrenia. Here we report the case of two residual schizophrenic patients refractory to conventional antipsychotics who showed a poor response to atypical antipsychotics. The combination of risperidone and clozapine produced a noticeable improvement in the patients' clinical status and a shortening of the treatment response latency.
Morera
A L
AL
Department of Internal Medicine and Psychiatry, Faculty of Medicine, University of La Laguna, Tenerife, Spain.
Barreiro
P
P
Cano-Muñoz
J L
JL
D000328:Adult; D003024:Clozapine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008875:Middle Aged; D018967:Risperidone / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy*
D003024:Clozapine; D018967:Risperidone