[Nosology and epidemiology of Horton's disease and polymyalgia rheumatica].
Giant cell arteritis is the most frequent of all vasculitides. Estimates of its incidence lies between 10 and 20 cases/100,000/year, and estimates of its prevalence in the population over 50 between 100 and 200/100,000/year. Giant cell arteritis affects primarily patients over 50, and the increased prevalence among women, partially reflects the sex distribution in this age group. The cause of the disease remains unknown, but a genetic predisposition (HLA-DR 4 group), has been clearly shown. Seasonal, and annual peaks of incidence have been shown in some studies, suggesting an infectious or environmental etiologic factor.
Duhaut
P
P
Service de médecine interne, Hôpital Edouard-Herriot, RECIF (Réseau d'épidémiologie clinique international francophone) Université Claude-Bernard, Lyon.
D000368:Aged; D005260:Female; D020022:Genetic Predisposition to Disease; D013700:Giant Cell Arteritis / Q000453:epidemiology* / Q000235:genetics; D015804:HLA-DR4 Antigen / Q000235:genetics; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011111:Polymyalgia Rheumatica / Q000453:epidemiology* / Q000235:genetics; D012737:Sex Factors
D015804:HLA-DR4 Antigen