Polychlorinated dibenzo-p-dioxins and related compounds: correlations of levels in human tissues and in blood.
We investigated PCDDs and related compounds levels in human tissue and blood obtained from the general population, and the correlation factor was calculated from the findings. None of the congeners in brain, muscle and lung were correlated except for 2,3,7,8-tetrachlorodibenzo-p-dioxin and octachlorodibenzo-p-dioxin in the brain (p < 0.05). In other tissues, all congeners had relatively good correlations to those in blood (r > 0.707). These congeners detected in blood were at high concentrations in the environment and human body. Therefore, we concluded that these congener levels in the blood might be useful for estimating these congener levels in human tissue.
Iida
T
T
Fukuoka Institute of Health & Environmental Sciences, Japan.
Hirakawa
H
H
Matsueda
T
T
Nagayama
J
J
Nagata
T
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001344:Autopsy; D005260:Female; D006801:Humans; D007536:Isomerism; D008297:Male; D008875:Middle Aged; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000097:blood / Q000493:pharmacokinetics; D012989:Soil Pollutants / Q000097:blood* / Q000493:pharmacokinetics*; D014018:Tissue Distribution
D000072317:Polychlorinated Dibenzodioxins; D012989:Soil Pollutants