Cystic hamartoma of the renal pelvis: a rare pathologic entity.
We report a case of a rare cystic renal tumor previously termed cystic hamartoma of the renal pelvis. A 53-year-old woman presented to her gynecologist with menometorrhagia. She subsequently had a computed tomographic scan that demonstrated an incidental cystic mass in the lower pole of the left kidney. Histologically, the tumor was composed of a mixture of benign mesenchymal and epithelial components. The stroma consisted of spindle cells with monomorphic nuclei and abundant eosinophilic cytoplasm that resembled smooth muscle and that reacted positively with antibodies to alpha-smooth muscle actin, desmin, and vimentin. The epithelial component was composed mostly of cysts lined by cuboidal-to-columnar epithelium. Focal dilated cysts were lined by epithelium with oncocytic features. We think that this entity is distinct from other renal tumors, including mesoblastic nephroma, cystic nephroma, or a cystic, partially differentiated nephroblastoma, and that it is best classified as a cystic hamartoma of the renal pelvis.
Mensch
L S
LS
Department of Pathology, University of Vermont, Burlington, USA.
Trainer
T D
TD
Plante
M K
MK
D005260:Female; D006222:Hamartoma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D007674:Kidney Diseases / Q000378:metabolism / Q000473:pathology*; D007682:Kidney Pelvis / Q000737:chemistry / Q000473:pathology*; D008875:Middle Aged; D018396:Mucin-1 / Q000032:analysis; D014746:Vimentin / Q000032:analysis
D018396:Mucin-1; D014746:Vimentin; D007633:Keratins