title: The clinical effect of ketoprofen after arthroscopic subacromial decompression: a randomized double-blind prospective study.
abstract: The purpose of the study was to evaluate the clinical effect of ketoprofen after arthroscopic subacromial decompression (ASD). The design was randomized, prospective, and double-blind, with a placebo control group. Forty-one consecutive patients with subacromial impingement syndrome, were randomized to treatment with ketoprofen 200 mg once daily or placebo for 6 weeks following ASD. For additional analgesia, patients used paracetamol if necessary. Clinical follow-up was performed at 6 weeks and at 2 years postoperatively. At the 6-week follow-up, the patients treated with ketoprofen had a statistically significant increase in UCLA total score (P<.05), range of movement (P<.05), and satisfaction (P<.05), and they had significantly less pain (P<.05). There was no statistical difference between the ketoprofen and placebo groups regarding strength. Patients receiving ketoprofen had significantly less need for additional analgesia (P<.05). At the 2-year follow-up, there were no differences in the scores between the ketoprofen and placebo group.
authors.affiliation: Department of Orthopaedics, University Hospital, Linköping, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Hoe-Hansen
authors.forename: R
authors.initials: R
authors.lastname: Norlin
mesh_terms: D000174:Acromion / Q000601:surgery*; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001182:Arthroscopy / Q000009:adverse effects*; D019299:Decompression, Surgical / Q000379:methods*; D004311:Double-Blind Method; D004724:Endoscopy / Q000009:adverse effects*; D005081:Exercise Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007660:Ketoprofen / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy* / Q000209:etiology / Q000534:rehabilitation; D017060:Patient Satisfaction; D011446:Prospective Studies; D019534:Shoulder Impingement Syndrome / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007660:Ketoprofen