title: Transcriptional analyses of the region of the equine herpesvirus type 4 genome encoding glycoproteins I and E.
abstract: To map the transcripts encoding the equine herpesvirus type 4 (EHV-4) glycoproteins I (gI) and E (gE), transcriptional analyses were performed at the right part of the unique short segment of EHV-4 genome. The results revealed that the gI gene is encoded by a 1.6-kb transcript which is 3' coterminal with a 3.0-kb gD mRNA while the gE gene is encoded by two transcripts of 3.5- and 2.4-kb in size. The transcriptional patterns described in this study for the EHV-4 gI and gE are similar to those found in the equivalent region of herpes simplex virus type 1 and feline herpesvirus type 1. Characterization of EHV-4 gI and gE glycoprotein genes may facilitate future studies to define their roles in the EHV-4 infection.
authors.affiliation: Department of Veterinary Microbiology, Faculty of Agriculture, University of Tokyo, Japan.
authors.forename: A M
authors.initials: AM
authors.lastname: Damiani
authors.forename: H K
authors.initials: HK
authors.lastname: Jang
authors.forename: T
authors.initials: T
authors.lastname: Matsumura
authors.forename: N
authors.initials: N
authors.lastname: Yokoyama
authors.forename: T
authors.initials: T
authors.lastname: Miyazawa
authors.forename: T
authors.initials: T
authors.lastname: Mikami
mesh_terms: D000818:Animals; D016679:Genome, Viral; D006736:Horses; D014158:Transcription, Genetic; D018140:Varicellovirus / Q000235:genetics*; D014759:Viral Envelope Proteins / Q000235:genetics*
chemical_list: D014759:Viral Envelope Proteins; C111845:glycoprotein I, Equine herpesvirus 4; C111846:glycoprotein e, Equid herpesvirus 4