title: Spinal cord arteriovenous malformations in two patients with hereditary hemorrhagic telangiectasia.
abstract: We report two cases, in first cousins, of spinal arteriovenous malformations (AVMs) of the perimedullary fistula type and hereditary hemorrhagic telangiectasia (HHT). Spinal AVMs are a rare clinical presentation of HHT, but can be the first manifestation in a child with this disorder. The importance of considering a coexisting disorder of vascular dysplasia, such as HHT, when a child presents with a spinal AVM is discussed.
authors.affiliation: Department of Medicine, St. Michael's Hospital, Toronto, Ontario, Canada.
authors.forename: J L
authors.initials: JL
authors.lastname: Mandzia
authors.forename: K G
authors.initials: KG
authors.lastname: terBrugge
authors.forename: M E
authors.initials: ME
authors.lastname: Faughnan
authors.forename: R H
authors.initials: RH
authors.lastname: Hyland
mesh_terms: D000792:Angiography; D001158:Arteries / Q000002:abnormalities*; D001165:Arteriovenous Malformations / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D002648:Child; D004621:Embolization, Therapeutic; D004844:Epistaxis; D006801:Humans; D007796:Laminectomy; D017116:Low Back Pain / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D010375:Pedigree; D013116:Spinal Cord / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000601:surgery; D013345:Subarachnoid Hemorrhage / Q000209:etiology; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications* / Q000235:genetics; D014057:Tomography, X-Ray Computed; D014680:Veins / Q000002:abnormalities*