Acute renal failure complicating high-dose intravenous immunoglobulin therapy for acquired haemophilia.
Acquired haemophilia is a rare disorder requiring therapy to control bleeding and to suppress the inhibitory antibody. High-dose intravenous immunoglobulin is commonly used as part of immunosuppressive regimens for this condition. We describe the case of an elderly patient who developed acute oliguric renal failure as a result of intravenous immunoglobulin therapy. All patients receiving such treatment should have renal function carefully monitored both during and after the infusion.
McColl
M D
MD
Haemophilia Centre, Royal Infirmary, Glasgow, UK. MMccoll1@aol.com
Omran
A
A
Walker
I D
ID
Lowe
G D
GD
D058186:Acute Kidney Injury / Q000209:etiology*; D000368:Aged; D000369:Aged, 80 and over; D004306:Dose-Response Relationship, Immunologic; D006467:Hemophilia A / Q000150:complications / Q000628:therapy*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male
D016756:Immunoglobulins, Intravenous