title: [Bilateral basal cell adenoma of the parotid gland and miltiple cylindromas of the skin--is there a syndromal coincidence?].
abstract: BACKGROUND
  Compared to the typical carcinomas of the upper aerodigestive tract the benign tumours of the salivary glands show significant histological diversity. Therefore correct histological diagnosis might be difficult even for the pathologist. Basal cell adenoma may have a multifocal origin and can be associated with cylindromas of the skin.
  
  
  METHODS
  In 17 patients with an average age of 65.8 a basal cell adenoma of a major salivary gland was diagnosed with a slight preponderance of the female sex (10:7).
  
  
  RESULTS
  One male patient showed a bilateral basal cell adenoma of the parotid gland and simultaneously multiple cylindromas of the skin in the head and neck region. There might be a syndromal coincidence, since histology revealed similar features of the salivary gland tumours compared to the skin neoplasias. The patient's history gave hints of a familial occurrence of the dermal cylindromas.
  
  
  CONCLUSIONS
  In rare cases a basal cell adenoma of the dermal type may be associated with cylindromas of the skin suggesting a common histogenesis. Due to possible multifocal origin and the menacing risk of malignant transformation a thorough follow-up of the patients after surgical treatment is mandatory.
authors.affiliation: Klinik für Hals-Nasen-Ohrenheilkunde, Medizinische Hochschule Hannover.
authors.forename: P R
authors.initials: PR
authors.lastname: Issing
mesh_terms: D000236:Adenoma / Q000473:pathology*; D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000473:pathology*; D012468:Salivary Gland Neoplasms / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*; D013577:Syndrome