Reactions of chloride salts of 7-amino-9-ethylguanine and 1-amino-3-methylbenzimidazoles with lead(IV) acetate: formation of 8-aza-9-ethylguanine and 1-methyl-1H-benzotriazoles.
Reaction of 7-amino-9-ethylguaninium chloride with lead(IV) acetate (LTA) in MeOH yielded 8-aza-9-ethylguanine. Similarly, the reaction of 1-amino-3-methylbenzimidazolium chloride or its substituted derivatives (6-methyl, 5,6-dimethyl and 5-nitro) with LTA gave the corresponding 1-methyl-1H-benzotriazole (or 1-methyl-2-azabenzimidazole) derivatives along with N-methylformananilide derivatives.
Kaiya
T
T
Faculty of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan.
Aoyama
S
S
Kohda
K
K
D001562:Benzimidazoles / Q000737:chemistry*; D006147:Guanine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D009942:Organometallic Compounds / Q000737:chemistry*; D014230:Triazoles / Q000138:chemical synthesis*
C119487:7-amino-9-ethylguanine; C119488:8-aza-9-ethylguanine; D001562:Benzimidazoles; D009942:Organometallic Compounds; D014230:Triazoles; D006147:Guanine; C008261:lead acetate