Paroxetine hydrochloride hemihydrate.
The structure of the title compound {systematic name: (3S-trans)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4- fluorophenyl)piperidinium chloride hemihydrate, C19H21FNO3+.Cl-.0.5H2O}, comprises two piperidinium cations (A and B), two chloride anions, and one water molecule in the asymmetric unit. A piperidinium proton of cation A is hydrogen bonded to the water molecule. The second proton points in the direction of one chloride anion, as does a piperidinium proton of cation B. One water proton points in the direction of another chloride anion.
Ibers
J A
JA
Department of Chemistry, Northwestern University, Evanston, IL 60208-3113, USA. ibers@chem.nwu.edu
D018687:Antidepressive Agents, Second-Generation / Q000737:chemistry*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D017374:Paroxetine / Q000737:chemistry*; D017367:Selective Serotonin Reuptake Inhibitors / Q000737:chemistry*
D018687:Antidepressive Agents, Second-Generation; D017374:Paroxetine; D017367:Selective Serotonin Reuptake Inhibitors