title: Haemophilus influenzae has a GM1 ganglioside-like structure and elicits Guillain-Barré syndrome.
abstract: The authors report a patient with an axonal Guillain-Barré syndrome (acute motor axonal neuropathy) associated with anti-GM1 antibody after Haemophilus influenzae infection. The result of ELISA inhibition studies and cytochemical staining with cholera toxin suggest the presence of a GM1-like structure on the surface of H. influenzae isolated from the patient. A particular strain of H. influenzae may have a GM1-like structure and may elicit an axonal Guillain-Barré syndrome.
authors.affiliation: Department of Neurology, Chiba University School of Medicine, Japan. morim@olive.ocn.ne.jp
authors.forename: M
authors.initials: M
authors.lastname: Mori
authors.forename: S
authors.initials: S
authors.lastname: Kuwabara
authors.forename: M
authors.initials: M
authors.lastname: Miyake
authors.forename: M
authors.initials: M
authors.lastname: Dezawa
authors.forename: E
authors.initials: E
authors.lastname: Adachi-Usami
authors.forename: H
authors.initials: H
authors.lastname: Kuroki
authors.forename: M
authors.initials: M
authors.lastname: Noda
authors.forename: T
authors.initials: T
authors.lastname: Hattori
mesh_terms: D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D005677:G(M1) Ganglioside / Q000276:immunology*; D006192:Haemophilus Infections / Q000150:complications*; D006193:Haemophilus influenzae / Q000276:immunology*; D006801:Humans; D008297:Male; D009431:Neural Conduction / Q000502:physiology; D011129:Polyradiculoneuropathy / Q000150:complications / Q000276:immunology* / Q000503:physiopathology
chemical_list: D005677:G(M1) Ganglioside