title: Prominent effect of immunoadsorption plasmapheresis therapy in a patient with chronic inflammatory demyelinating polyneuropathy associated with hepatitis B infection.
abstract: We encountered a patient with chronic inflammatory demyelinating polyneuropathy associated with hepatitis B infection. Immunohistochemical study revealed the deposition of immune complex composed of hepatitis B surface antigen (HBsAg) both around the endoneural capillary and in the endoneurium. Neurological signs were significantly improved by immunoadsorption plasmapheresis (IAPP) treatment without incorporating corticosteroid hormone therapy; weekly long-term IAPP has successfully maintained the patient's condition.
authors.affiliation: Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Inoue
authors.forename: K
authors.initials: K
authors.lastname: Oguchi
authors.forename: T
authors.initials: T
authors.lastname: Iwahashi
authors.forename: H
authors.initials: H
authors.lastname: Arakura
authors.forename: C S
authors.initials: CS
authors.lastname: Koh
mesh_terms: D000936:Antigen-Antibody Complex / Q000032:analysis; D002908:Chronic Disease; D003711:Demyelinating Diseases / Q000628:therapy*; D005260:Female; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D019694:Hepatitis B, Chronic / Q000150:complications*; D006801:Humans; D007163:Immunosorbent Techniques; D008875:Middle Aged; D010525:Peripheral Nerves / Q000276:immunology; D010956:Plasmapheresis; D011115:Polyneuropathies / Q000628:therapy*
chemical_list: D000936:Antigen-Antibody Complex; D006514:Hepatitis B Surface Antigens