title: A framework for drug utilization evaluation in depression: insights from outcomes research.
abstract: BACKGROUND
  Drug utilization evaluation (DUE) offers the prospect of improving the quality of care in depression by focusing on drug-related problems (DRPs). Outcomes research in depression can provide a basis on which to address difficulties in implementing DUE programs in the outpatient environment of managed care.
  
  
  OBJECTIVE
  The purpose of this paper is to facilitate the development of a drug utilization evaluation program for depressed patients receiving care in an outpatient environment.
  
  
  METHODS
  The literature was reviewed in the area of depression treatment, drug-related problems, and current outcomes research. This information was synthesized into a framework with potential DUE criteria.
  
  
  CONCLUSIONS
  The quality of care for depression can be improved if these efforts are focused on solving DRPs. Outcomes research findings may be used as the basis for developing DUE criteria and as a first step in selecting and targeting interventions.
authors.affiliation: Global Health Economics Research, Eli Lilly and Company, Indianapolis, IN 46285, USA.
authors.forename: E T
authors.initials: ET
authors.lastname: Edgell
authors.forename: K H
authors.initials: KH
authors.lastname: Summers
authors.forename: T R
authors.initials: TR
authors.lastname: Hylan
authors.forename: J
authors.initials: J
authors.lastname: Ober
authors.forename: J L
authors.initials: JL
authors.lastname: Bootman
mesh_terms: D000553:Ambulatory Care / Q000592:standards; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy*; D017723:Drug Utilization Review / Q000379:methods*; D006801:Humans; D008329:Managed Care Programs / Q000592:standards; D017063:Outcome Assessment, Health Care / Q000379:methods*; D011785:Quality Assurance, Health Care; D014481:United States
chemical_list: D000928:Antidepressive Agents