Occurrence of gouty tophi following acitretin therapy.
Acitretin (Ro 10-1670 or Neotigason), a free acid and the main metabolite of etretinate (Ro 10-9359 or Tigason), is the most recent of the retinoids used orally in the treatment of psoriasis and numerous other dermatoses exhibiting disorders of keratinization. In the majority of cases, its side-effects are similar to those of hypervitaminosis A.
Vanhooteghem
O
O
Department of Dermatology and Venereology, University Hospital St Pierre, 129, Boulevard de Waterloo, B 1000, Brussel, Belgium.
Andre
J
J
Pochet
J M
JM
Demaubeuge
J
J
Song
M
M
D017255:Acitretin / Q000009:adverse effects*; D000368:Aged; D000369:Aged, 80 and over; D002118:Calcium / Q000652:urine; D006073:Gout / Q000139:chemically induced*; D006801:Humans; D007641:Keratolytic Agents / Q000009:adverse effects*; D008297:Male
D007641:Keratolytic Agents; D017255:Acitretin; D002118:Calcium