Identification of a peptide from mammal albumins responsible for enhanced pigment production by group B streptococci.
The peptide from peptones responsible for enhanced pigment production by Streptococcus agalactiae in culture media has been isolated from a peptic digest of human albumin and has been identified as Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe. The related heptapeptide lacking the N-terminal Ile also had pigment-enhancing activity. A sequence similarity search showed that these sequences are present only in mammal albumins.
Rosa-Fraile
M
M
Microbiology Service, Virgen de las Nieves Hospital, 18014 Granada, Spain. delarosa@cica.es
Sampedro
A
A
Varela
J
J
Garcia-Peña
M
M
Gimenez-Gallego
G
G
D000818:Animals; D002417:Cattle; D003470:Culture Media / Q000737:chemistry; D006801:Humans; D009842:Oligopeptides / Q000737:chemistry / Q000494:pharmacology; D010860:Pigments, Biological / Q000096:biosynthesis*; D012709:Serum Albumin / Q000737:chemistry*; D013290:Streptococcal Infections / Q000382:microbiology; D013292:Streptococcus agalactiae / Q000254:growth & development* / Q000378:metabolism*
D003470:Culture Media; D009842:Oligopeptides; D010860:Pigments, Biological; D012709:Serum Albumin