Malayenolides A-D, novel diterpenes from the indonesian sea pen veretillum malayense
Malayenolides A-D (1-4), four new briarane diterpenes, were isolated from the sea pen Veretillum malayense collected in Indonesia. The new diterpenes possess benzoate and senecioate substitutents, both of which are rare among marine natural products. The structures of the new compounds were determined from spectral data. Compounds 1-4 are toxic to brine shrimp.
Fu
X
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, and Department of Invertebrate Zoology, California Academy of Sciences, Golden Gate Park, San Francisco, California 94118, USA.
Schmitz
FJ
Williams
GC