title: [Glucocorticoid deficiency of the adrenal cortex in chronic liver diseases].
abstract: OBJECTIVE
  The study of blood levels of hydrocortisone and ACTH in patients with chronic hepatic lesions.
  
  
  METHODS
  Blood levels of hydrocortisone and ACTH were measured in 198 patients with chronic liver diseases (CLD) of different etiology and severity and in 39 healthy controls.
  
  
  RESULTS
  Blood hydrocortisone was subnormal while ACTH elevated in all the patients except those with chronic hepatitis running a favorable course. Changes in the hydrocortisone and ACTH content were the greatest in CLD of viral and autoimmune etiology, the least--of alcoholic etiology.
  
  
  CONCLUSIONS
  Hydrocortisone deficiency was most prominent in severe hepatic lesions.
authors.forename: O V
authors.initials: OV
authors.lastname: Astaf'eva
authors.forename: A S
authors.initials: AS
authors.lastname: Loginov
mesh_terms: D000293:Adolescent; D000302:Adrenal Cortex / Q000378:metabolism*; D000309:Adrenal Insufficiency / Q000097:blood* / Q000209:etiology; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000172:deficiency*; D008107:Liver Diseases / Q000097:blood* / Q000209:etiology; D008297:Male; D008875:Middle Aged
chemical_list: D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone