[Retrospective study of the incidence of hepatitis G virus infection in transfused patients].
BACKGROUND
Recently the parenteral transmission of hepatitis G virus (HGV) has been shown. The aim of the study was to investigate the incidence of post-transfusion HGV.


METHODS
HGV (RNA-HGV and anti-HGVE2) were retrospectively studied in 140 transfused patients.


RESULTS
12 (8.6%) were infected after transfusion: 9 of 12 (75%) the RNA-HGV remained detectable after 6 months and 3 (25%) seroconverted to anti-HGVE2. No patient had post-transfusional hepatitis criteria. In 5 (42%) the transaminases levels were slightly increased. The clinical evolution was favourable. No significant differences were found between patients with or without HGV infection.


CONCLUSIONS
HGV is an agent associated with transfusion but it carries a low pathogenic capability.
Salmerón
J
J
Servicio de Aparato Digestivo, Hospital Clínico San Cecilio, Granada.
Carmona
I
I
Torres
C
C
Muñoz de Rueda
P
P
Gila
A
A
Ruiz-Extremera
A
A
D000293:Adolescent; D000328:Adult; D002648:Child; D004796:Clinical Enzyme Tests; D015331:Cohort Studies; D003627:Data Interpretation, Statistical; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D018067:Flaviviridae / Q000235:genetics / Q000276:immunology; D006508:Hepatitis Antibodies / Q000032:analysis; D006525:Hepatitis, Viral, Human / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D006801:Humans; D008297:Male; D012367:RNA, Viral / Q000032:analysis; D012189:Retrospective Studies; D013997:Time Factors; D000637:Transaminases / Q000097:blood; D065227:Transfusion Reaction
D006508:Hepatitis Antibodies; D012367:RNA, Viral; D000637:Transaminases