title: Use of ADCON in neurosurgery: preclinical review.
abstract: ADCON-L and ADCON-T/N are two bioabsorbable adhesion barrier gels designed to inhibit post-operative fibrosis around the dura and nerve structure. Two ADCON products were evaluated in animal models emulating their use in neurosurgery. In all studies ADCON-L and ADCON-T/N were safe and effective barriers to post-operative peridural and perineural fibrosis.
authors.affiliation: Gliatech Inc., Cleveland, Ohio 44122, USA.
authors.forename: H
authors.initials: H
authors.lastname: Lo
authors.forename: R C
authors.initials: RC
authors.lastname: Frederickson
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D017586:Diskectomy / Q000009:adverse effects; D004353:Drug Evaluation, Preclinical; D005355:Fibrosis / Q000517:prevention & control; D005782:Gels / Q000627:therapeutic use*; D007796:Laminectomy / Q000009:adverse effects; D009493:Neurosurgery; D009930:Organic Chemicals; D011183:Postoperative Complications / Q000517:prevention & control*
chemical_list: C104199:ADCON-L; D005782:Gels; D009930:Organic Chemicals