title: Anti-allergic action of resveratrol and related hydroxystilbenes.
abstract: Resveratrol (1) and nine related hydroxystilbene compounds (2 approximately 9) isolated from plants were evaluated for the anti-allergic activities in vitro. Resveratrol (1) and rhapontigenin (5) demonstrated significant inhibitions upon the release of beta-hexosaminidase from the cultured RBL-2H3 cells in a dose-dependent manner and the IC50 values were calculated as 14 and 15 microM, respectively.
authors.forename: H
authors.initials: H
authors.lastname: Cheong
authors.forename: S Y
authors.initials: SY
authors.lastname: Ryu
authors.forename: K M
authors.initials: KM
authors.lastname: Kim
mesh_terms: D018926:Anti-Allergic Agents / Q000737:chemistry / Q000494:pharmacology*; D002460:Cell Line; D000077185:Resveratrol; D013267:Stilbenes / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D018926:Anti-Allergic Agents; D013267:Stilbenes; D000077185:Resveratrol