Basic research conducted on alloplant biomaterials.
OBJECTIVE
To reduce antigenicity of allografts and stimulate their replacement by natural recipient tissues.


METHODS
Experimental allotransplantation of different tissues (fascias, tendons, derma, fat, etc.) with histological, histochemical, electron microscopical, electron histochemical examination 3, 5, 7, 14, 21, 30, 60, 120, 180 and 360 days postoperatively.


RESULTS
Allografts of different tissues with glucosaminoglycans extracted from collagen fibers have low antigenicity and can be replaced by natural tissues. Allografts with these properties were named 'Alloplant'.


CONCLUSIONS
Alloplant biomaterials can selectively stimulate natural tissue regeneration. Hence, Alloplant biomaterials can be utilized in surgery for the restoration of different tissues.
Muldashev
E R
ER
Russian Eye and Plastic Surgery Center, Ufa, Russia.
Muslimov
S A
SA
Nigmatullin
R T
RT
Kiiko
Y I
YI
Galimova
V U
VU
Salikhov
A Y
AY
Selsky
N E
NE
Bulatov
R T
RT
Musina
L A
LA
D000273:Adipose Tissue / Q000166:cytology / Q000378:metabolism / Q000637:transplantation; D000293:Adolescent; D000328:Adult; D000818:Animals; D001672:Biocompatible Materials; D003228:Conjunctiva / Q000166:cytology / Q000601:surgery*; D005143:Eyelids / Q000166:cytology / Q000601:surgery*; D005206:Fascia Lata / Q000166:cytology / Q000378:metabolism / Q000637:transplantation; D006025:Glycosaminoglycans / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D007519:Isoantigens / Q000378:metabolism; D008875:Middle Aged; D011817:Rabbits; D051381:Rats; D012590:Sclera / Q000166:cytology / Q000378:metabolism / Q000637:transplantation; D013710:Tendons / Q000166:cytology / Q000378:metabolism / Q000637:transplantation; D016378:Tissue Transplantation; D014184:Transplantation, Homologous
D001672:Biocompatible Materials; D006025:Glycosaminoglycans; D007519:Isoantigens