title: [Acute acalculous cholecystitis associated with primary antiphospholipid antibody syndrome. Cure with low-molecular-weight heparin and antivitamin K].
abstract: We report the first case of acute acalculous cholecystitis associated with primary antiphospholipid-antibody syndrome. The diagnosis was serological and was based on positive tests for lupus anticoagulant or anticardiolipin antibodies. The treatment was exclusively medical. Cholecystitis was cured with low-molecular weight heparin and oral anticoagulants. A rapid diagnosis can prevent lack of therapeutic errors such as surgery, antibiotherapy or corticotherapy, and long-term anticoagulant treatment can be proposed to prevent recurrent thrombosis.
authors.affiliation: Service de Gastroentérologie, Centre Hospitalier Général Robert-Ballanger, Aulnay-sous-Bois.
authors.forename: N
authors.initials: N
authors.lastname: Nolen
authors.forename: G
authors.initials: G
authors.lastname: Bellaiche
authors.forename: C
authors.initials: C
authors.lastname: Warmberg
authors.forename: A
authors.initials: A
authors.lastname: Nouts
authors.forename: G
authors.initials: G
authors.lastname: Ley
authors.forename: J L
authors.initials: JL
authors.lastname: Slama
mesh_terms: D000208:Acute Disease; D000284:Administration, Oral; D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use*; D016736:Antiphospholipid Syndrome / Q000150:complications*; D002764:Cholecystitis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D014463:Ultrasonography; D014812:Vitamin K / Q000037:antagonists & inhibitors*
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; D014812:Vitamin K