Early temporal expression of soluble cellular adhesion molecules in patients with unstable angina and subendocardial myocardial infarction.
Inflammation is increasingly considered to be involved in the pathogenesis of acute coronary syndromes. We documented persistent elevation in the levels of soluble ICAM-1 and soluble VCAM-1 and a decrease in the levels of soluble E-selectin in the first 72 hours of acute presentation in patients with unstable angina and subendocardial myocardial infarction.
Mulvihill
N
N
Royal City of Dublin Hospital Research and Education Institute, Department of Cardiology, St. James's Hospital, Ireland. mulvihin@tcd.ie
Foley
J B
JB
Ghaisas
N
N
Murphy
R
R
Crean
P
P
Walsh
M
M
D000789:Angina, Unstable / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D019040:E-Selectin / Q000097:blood; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000096:biosynthesis*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D011379:Prognosis; D012720:Severity of Illness Index; D019010:Vascular Cell Adhesion Molecule-1 / Q000096:biosynthesis*
D015415:Biomarkers; D019040:E-Selectin; D019010:Vascular Cell Adhesion Molecule-1; D018799:Intercellular Adhesion Molecule-1