title: [Immunological investigation of hypogammaglobulinemia].
abstract: Immunoglobulin deficiency syndromes should be considered in patients with recurrent respiratory tract infections or in patients with infections caused by agents of low virulence. We present two patients with a clinical history of recurrent respiratory tract infections. Both patients had a humoral immunodeficiency characterised as common variable immunodeficiency (CVID). We give a brief survey of CVID with emphasis on the immunological investigation of hypogamma-globulinaemia. Analysis of serum, immunoglobulins should be performed in patients with recurrent infections Patients with humoral immuno-deficiency often have false negative serology for infectious agents despite obvious infections.
authors.affiliation: Avdeling for mikrobiologi og immunologi Gades Institutt, Haukeland Sykehus, Bergen.
authors.forename: R
authors.initials: R
authors.lastname: Jureen
authors.forename: E
authors.initials: E
authors.lastname: Ulvestad
mesh_terms: D000293:Adolescent; D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications / Q000175:diagnosis / Q000276:immunology*; D017074:Common Variable Immunodeficiency / Q000150:complications / Q000175:diagnosis / Q000276:immunology*; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000172:deficiency; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D012141:Respiratory Tract Infections / Q000276:immunology / Q000382:microbiology; D014777:Virus Diseases / Q000209:etiology / Q000276:immunology
chemical_list: D007136:Immunoglobulins