title: [Homicide and hebephrenia-like syndrome in metachromatic leukodystrophy].
abstract: We report a patient with metachromatic leukodystrophy (MLD) with a first manifestation of homicide. On admission the patient showed a hebephrenia-like syndrome with inappropriate affect, thought disorder and behavioral changes. Magnetic resonance tomography (MRT) findings suggested a diagnosis of MLD, which was confirmed by a decreased activity of leucocyte arylsulfatase A and an excessive urinary sulfatide excretion.
authors.affiliation: Klinik und Poliklinik für Psychiatrie und Psychotherapie, Technischen Universität München.
authors.forename: M
authors.initials: M
authors.lastname: Rentrop
authors.forename: K
authors.initials: K
authors.lastname: Hakk
authors.forename: F J
authors.initials: FJ
authors.lastname: Freisleder
authors.forename: W
authors.initials: W
authors.lastname: Kissling
authors.forename: G
authors.initials: G
authors.lastname: Kockott
mesh_terms: D000293:Adolescent; D000328:Adult; D001192:Arylsulfatases; D003937:Diagnosis, Differential; D006708:Homicide / Q000523:psychology*; D006801:Humans; D007966:Leukodystrophy, Metachromatic / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D012562:Schizophrenia, Disorganized / Q000175:diagnosis*; D013577:Syndrome
chemical_list: D001192:Arylsulfatases