title: Parasagittal solitary fibrous tumor of the meninges. Case report and review of the literature.
abstract: The clinical, radiologic and pathologic features of a case of parasagittal solitary fibrous tumor of the meninges are reported. The patient was a 44 year-old male who presented with a complex partial seizure and a history of headaches and confusion. Radiological studies showed a large extra-axial dural-based mass in the right parietal region, predominantly isointense with gray matter and hypointense with respect to white matter on T1-weighted images, and hypointense with respect to gray matter on T2-weighted images. At surgery, the mass was very vascular, quite firm and very adherent to the convexity. Histologically the tumor was composed of spindle-shaped cells growing in fascicles within a collagenous matrix. Solitary fibrous tumor of the meninges is a newly described entity, which should be kept in mind in the clinical and radiological differential diagnosis of extra-axial brain tumors.
authors.affiliation: Neurosurgical Laboratories, Brigham & Women's Hospital, Boston, Massachusetts, USA.
authors.forename: D C
authors.initials: DC
authors.lastname: Nikas
authors.forename: U
authors.initials: U
authors.lastname: De Girolami
authors.forename: R D
authors.initials: RD
authors.lastname: Folkerth
authors.forename: L
authors.initials: L
authors.lastname: Bello
authors.forename: A A
authors.initials: AA
authors.lastname: Zamani
authors.forename: P M
authors.initials: PM
authors.lastname: Black
mesh_terms: D000328:Adult; D018952:Antigens, CD34 / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000276:immunology / Q000473:pathology*; D008579:Meningioma / Q000276:immunology / Q000473:pathology; D018218:Neoplasms, Fibrous Tissue / Q000276:immunology / Q000473:pathology*; D010296:Parietal Lobe / Q000473:pathology*; D011379:Prognosis
chemical_list: D018952:Antigens, CD34; D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor