title: Cytotoxic constituents from the roots of Anthriscus sylvestris.
abstract: Activity-guided fractionation of the roots of Anthriscus sylvestris resulted in the isolation and characterization of five cytotoxic compounds, deoxypodophyllotoxin (1), falcarindiol (2), and angeloyl podophyllotoxin (5) from the hexane soluble fraction and morelensin (3), bursehernin (4) from the chloroform soluble fraction. It is the first report of the occurrence of compound 5 in nature.
authors.affiliation: R&D Centre, Dong-wha Pharmaceutical Ind. Co., Ltd, Anyang City, Korea.
authors.forename: Y H
authors.initials: YH
authors.lastname: Lim
authors.forename: M J
authors.initials: MJ
authors.lastname: Leem
authors.forename: D H
authors.initials: DH
authors.lastname: Shin
authors.forename: H B
authors.initials: HB
authors.lastname: Chang
authors.forename: S W
authors.initials: SW
authors.lastname: Hong
authors.forename: E Y
authors.initials: EY
authors.lastname: Moon
authors.forename: D K
authors.initials: DK
authors.lastname: Lee
authors.forename: S J
authors.initials: SJ
authors.lastname: Yoon
authors.forename: W S
authors.initials: WS
authors.lastname: Woo
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal / Q000737:chemistry*; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic