title: [Perspectives and possibilities of luminescent differential diagnosis in endoscopy of stomach ulcers].
abstract: On the basis of 1800 examinations of tumor cells the authors show possibility for accumulation of luminescent dye uranine by malignant cells. The conception of the mechanism of its accumulation, confirmed by the studies of reinoculated tumors of rats (60 examinations) is presented. Of 821 patients with ulcers of the stomach 641 had no luminescence; at repeated examination cancer and ulcer were revealed in 7 of them. Malignant transformation was verified by histologic method in 102 of 180 patients with luminescent ulcers. In 22 patients intestinal metaplasia was detected in the luminescence areas and in 40--there was a rough epitnelial dysplasia. At the examination of these patients two years later, cancer of the stomach at the sites of previously revealed luminescence was detected in 15 patients (26.3%).
authors.forename: V I
authors.initials: VI
authors.lastname: Polsachev
authors.forename: S P
authors.initials: SP
authors.lastname: Alekseĭtseva
authors.forename: V V
authors.initials: VV
authors.lastname: Lazarev
authors.forename: O V
authors.initials: OV
authors.lastname: Braginskaia
mesh_terms: D000818:Animals; D003287:Contrast Media; D003937:Diagnosis, Differential; D019793:Fluorescein; D005500:Follow-Up Studies; D005773:Gastroscopy / Q000379:methods*; D006801:Humans; D008163:Luminescent Measurements; D051381:Rats; D013274:Stomach Neoplasms / Q000175:diagnosis; D013276:Stomach Ulcer / Q000175:diagnosis*
chemical_list: D003287:Contrast Media; D019793:Fluorescein