Anti-allergic action of resveratrol and related hydroxystilbenes.
Resveratrol (1) and nine related hydroxystilbene compounds (2 approximately 9) isolated from plants were evaluated for the anti-allergic activities in vitro. Resveratrol (1) and rhapontigenin (5) demonstrated significant inhibitions upon the release of beta-hexosaminidase from the cultured RBL-2H3 cells in a dose-dependent manner and the IC50 values were calculated as 14 and 15 microM, respectively.
Cheong
H
H
Ryu
S Y
SY
Kim
K M
KM
D018926:Anti-Allergic Agents / Q000737:chemistry / Q000494:pharmacology*; D002460:Cell Line; D000077185:Resveratrol; D013267:Stilbenes / Q000737:chemistry / Q000494:pharmacology*
D018926:Anti-Allergic Agents; D013267:Stilbenes; D000077185:Resveratrol