Lipoprotein (a) immunapheresis in the treatment of familial lipoprotein (a) hyperlipoproteinemia in a patient with coronary heart disease.
This paper reports 2 years' experience with lipoprotein (a) (Lp[a]) immunapheresis which was successfully handled on a now 40-year-old patient with familial Lp(a) hyperlipoproteinemia inducing severe coronary heart disease with 2 myocardial infarctions and diffuse coronary sclerosis. Continued treatment by Lp(a) immunabsorption with specific sheep antibodies reduced stenosis in coronary vessels more than 50% and stopped the progression of coronary heart disease. A special apheresis technique and the results of continued absorption effects are described.
Straube
R
R
Department of Nephrology, District Hospital, Lüdenscheid, Germany.
Kingreen
H
H
D000328:Adult; D001781:Blood Component Removal; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D003331:Coronary Vessels / Q000473:pathology; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D006951:Hyperlipoproteinemias / Q000150:complications / Q000235:genetics* / Q000628:therapy; D007164:Immunosorbents / Q000627:therapeutic use; D017270:Lipoprotein(a) / Q000097:blood*; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology; D012598:Sclerosis
D007164:Immunosorbents; D017270:Lipoprotein(a)