title: Coronary bypass grafting without cardiopulmonary bypass--technical considerations, clinical results, and follow-up.
abstract: BACKGROUND
  Coronary bypass surgery can be performed less invasively by avoiding cardiopulmonary bypass (CPB). We present our early 'off pump' coronary bypass surgery experience in combination with a minithoracotomy or sternotomy.
  
  
  METHODS
  Between 11/1996 and 12/1997 312 patients were included in a prospective study, 223 (Group A) underwent an antero-lateral minithoracotomy (MIDCAB) and 89 (Group B) had a full sternotomy (OPCAB). ITA harvesting and anastomosis was performed under direct vision in all cases. Different devices for local mechanical immobilization were used to perform the anastomosis.
  
  
  RESULTS
  In 212 patients of group A revascularization was by a single ITA graft and in 11 patients by a double graft using the radial artery as a T graft. Conversion to sternotomy and cardiopulmonary bypass was necessary in 12 (5.3%) patients. Intraoperative myocardial infarction was observed in 5 patients (2.2%). Early-postoperative reoperation due to graft failure was necessary in 5 patients (2.2%). Mortality was 0.4% (one patient). The early postoperative graft patency rate was 97.1% as confirmed by angiography. In group B, 25 patients had single graft and 64 patients multiple graft revascularization. Intraoperative conversion to CPB was necessary in 10 patients (11.2%). Intraoperative myocardial infarction occurred in 1 patient (1.1%), postoperative low output syndrome in 2 patients (2.2%). Early postoperative reoperation due to graft failure was necessary in 1 patient (1.1%). Mortality was 1.1%. Angiographic control of 48 patients after 6 months confirmed a patency rate of 92.6%.
  
  
  CONCLUSIONS
  Coronary bypass surgery without using cardiopulmonary bypass is safe to achieve good early and mid-term results. MIDCAB is a minimally invasive technique. Experienced surgeons should be ready to compete with PTCA techniques.
authors.affiliation: University of Leipzig, Heart Center, Department of Cardiac Surgery, Germany. diea@server3.medizin.uni-leipzig.de
authors.forename: A
authors.initials: A
authors.lastname: Diegeler
authors.forename: M
authors.initials: M
authors.lastname: Matin
authors.forename: V
authors.initials: V
authors.lastname: Falk
authors.forename: R
authors.initials: R
authors.lastname: Battellini
authors.forename: T
authors.initials: T
authors.lastname: Walther
authors.forename: R
authors.initials: R
authors.lastname: Autschbach
authors.forename: F W
authors.initials: FW
authors.lastname: Mohr
mesh_terms: D002315:Cardiopulmonary Bypass; D017023:Coronary Angiography; D001026:Coronary Artery Bypass / Q000379:methods*; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000601:surgery*; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D011183:Postoperative Complications; D011446:Prospective Studies; D017534:Radial Artery / Q000637:transplantation; D013249:Sternum / Q000601:surgery; D013908:Thoracotomy / Q000379:methods; D016896:Treatment Outcome