title: [Severe potassium dichromate poisoning after accidental nasal introduction].
abstract: BACKGROUND
  Nasal foreign body (NFB) is a common situation in pediatrics. Poisoning is a rare complication of NFB insertion. We report a case of acute potassium dichromate poisoning secondary to NFB insertion.
  
  
  METHODS
  Six days after insertion of a NFB, progressive occurrence of diarrhea, vomiting, nasal obstruction, acute renal failure, pancreatitis, hepatitis and drowsiness justified hospitalization of a 3-year-old girl in the pediatric intensive care unit. Acute potassium dichromate poisoning was confirmed by high plasma chromium level and by the spectrophotometric analysis of the crystal. Recovery was satisfactory with supportive treatment. An official survey allowed to discover that the crystal was freely sold and that its toxicity was unknown by dealers, while no information was given to the customers.
  
  
  CONCLUSIONS
  Transmucosal absorption of toxics is an unusual severe potential hazard that should be evoked to allow a rapid management. After the discovery and withdrawal of a NFB, occurrence of systemic symptoms, even trivial, must make one suspect a poisoning. In this circumstance, analysis of the foreign body should be done, associated with toxicologic dosages. This case report illustrates that potassium dichromate poisoning is a severe medical condition and that its clinical presentation assume a large widespread of symptoms due to multiple organ involvement.
authors.affiliation: Département d'anesthésie, CHU Timone, Marseille, France.
authors.forename: N
authors.initials: N
authors.lastname: André
authors.forename: O
authors.initials: O
authors.lastname: Paut
authors.forename: J
authors.initials: J
authors.lastname: Arditti
authors.forename: P
authors.initials: P
authors.lastname: Fabre
authors.forename: V
authors.initials: V
authors.lastname: Bremond
authors.forename: T
authors.initials: T
authors.lastname: Alhmana
authors.forename: J F
authors.initials: JF
authors.lastname: Bellus
authors.forename: J
authors.initials: J
authors.lastname: Jouglard
authors.forename: J
authors.initials: J
authors.lastname: Camboulives
mesh_terms: D000042:Absorption; D000281:Administration, Intranasal; D002675:Child, Preschool; D005260:Female; D005547:Foreign Bodies; D006801:Humans; D009297:Nasal Mucosa / Q000502:physiology; D011041:Poisoning / Q000097:blood / Q000503:physiopathology; D011192:Potassium Dichromate / Q000008:administration & dosage / Q000506:poisoning*
chemical_list: D011192:Potassium Dichromate