Mechanical properties of powders for compaction and tableting: an overview.
This review provides an insight into mechanical properties that are critical to understanding powder processing for tableting. Various parameters that reflect these basic fundamental properties of powder and their evaluation by different techniques are described. Some recent examples in which these techniques are used in drug substance selection, formulation optimization or scale-up are also provided.
Jain
S
Glaxo Wellcome Inc., Pharmaceutics and Chemical Analysis, PO Box 13398, Research Triangle Park, NC 27709-3398, USA.