title: Improvement in naltrexone treatment compliance with contingency management.
abstract: The efficacy of a voucher-based incentive program for improving adherence to outpatient, thrice weekly naltrexone maintenance was tested in a three group, randomized, 12-week clinical trial. Voucher incentives were given as follows: contingent group (n = 19) for each consecutive naltrexone dose ingested; non-contingent group (n = 19) on unpredictable schedule independently of taking naltrexone; no-voucher group (n = 20) none. Vouchers were exchangeable for goods and services. The contingent group had significantly longer treatment retention and ingested significantly more doses of naltrexone (consecutive and total) than either control group. Voucher incentives can significantly increase adherence to naltrexone maintenance in recently detoxified opioid dependent individuals.
authors.affiliation: NIDA Intramural Research Program, NIH Addiction Research Centre, Baltimore, MD 21224, USA.
authors.forename: K L
authors.initials: KL
authors.lastname: Preston
authors.forename: K
authors.initials: K
authors.lastname: Silverman
authors.forename: A
authors.initials: A
authors.lastname: Umbricht
authors.forename: A
authors.initials: A
authors.lastname: DeJesus
authors.forename: I D
authors.initials: ID
authors.lastname: Montoya
authors.forename: C R
authors.initials: CR
authors.lastname: Schuster
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001521:Behavior Therapy / Q000379:methods* / Q000592:standards; D016009:Chi-Square Distribution; D005260:Female; D006556:Heroin Dependence / Q000523:psychology / Q000534:rehabilitation* / Q000652:urine; D006801:Humans; D008297:Male; D008875:Middle Aged; D009271:Naltrexone / Q000008:administration & dosage* / Q000009:adverse effects; D009292:Narcotic Antagonists / Q000008:administration & dosage* / Q000009:adverse effects; D010349:Patient Compliance / Q000523:psychology / Q000706:statistics & numerical data; D011446:Prospective Studies; D015813:Substance Abuse Detection / Q000706:statistics & numerical data; D014040:Token Economy; D016896:Treatment Outcome
chemical_list: D009292:Narcotic Antagonists; D009271:Naltrexone