title: Radiation induced liver injury detected by particulate reticuloendothelial contrast agent.
abstract: Radiation induced liver injury detected by a particulate reticuloendothelial MR contrast agent is described in a patient with metastatic colon cancer. The irradiated hepatic parenchyma failed to darken after ferumoxide administration. This finding suggests that detection of metastatic disease after ferumoxide contrast agents may be impaired in patients who have previously received upper abdominal radiation treatment.
authors.affiliation: Academic Department of Diagnostic Radiology, Royal Marsden NHS Trust, Sutton, Surrey, UK.
authors.forename: A R
authors.initials: AR
authors.lastname: Padhani
authors.forename: J E
authors.initials: JE
authors.lastname: Husband
authors.forename: D
authors.initials: D
authors.lastname: Gueret Wardle
mesh_terms: D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology; D003287:Contrast Media; D003911:Dextrans; D052203:Ferrosoferric Oxide; D006801:Humans; D007501:Iron; D008107:Liver Diseases / Q000175:diagnosis* / Q000209:etiology; D008113:Liver Neoplasms / Q000532:radiotherapy / Q000556:secondary; D008279:Magnetic Resonance Imaging / Q000379:methods*; D058185:Magnetite Nanoparticles; D008297:Male; D010087:Oxides; D011832:Radiation Injuries / Q000175:diagnosis* / Q000209:etiology
chemical_list: D003287:Contrast Media; D003911:Dextrans; D058185:Magnetite Nanoparticles; D010087:Oxides; D007501:Iron; C065507:ferumoxides; D052203:Ferrosoferric Oxide