title: Deconstructing vancomycin.
authors.affiliation: Department of Biological Chemistry and Molecular Pharmacoloy, Harvard Medical School, Boston, MA 02115, USA. walsh@med.harvard.edu
authors.forename: C
authors.initials: C
authors.lastname: Walsh
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000378:metabolism; D002473:Cell Wall / Q000378:metabolism; D004151:Dipeptides / Q000737:chemistry / Q000378:metabolism; D004187:Disaccharides / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D015195:Drug Design; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism; D006031:Glycosylation; D006602:Hexosyltransferases / Q000037:antagonists & inhibitors / Q000378:metabolism; D006860:Hydrogen Bonding; D010457:Peptidoglycan / Q000096:biosynthesis* / Q000378:metabolism; D046928:Peptidoglycan Glycosyltransferase; D013329:Structure-Activity Relationship; D014640:Vancomycin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D004151:Dipeptides; D004187:Disaccharides; D010457:Peptidoglycan; C002956:alanylalanine; D014640:Vancomycin; D006602:Hexosyltransferases; D046928:Peptidoglycan Glycosyltransferase