Cytotoxic constituents from the roots of Anthriscus sylvestris.
Activity-guided fractionation of the roots of Anthriscus sylvestris resulted in the isolation and characterization of five cytotoxic compounds, deoxypodophyllotoxin (1), falcarindiol (2), and angeloyl podophyllotoxin (5) from the hexane soluble fraction and morelensin (3), bursehernin (4) from the chloroform soluble fraction. It is the first report of the occurrence of compound 5 in nature.
Lim
Y H
YH
R&D Centre, Dong-wha Pharmaceutical Ind. Co., Ltd, Anyang City, Korea.
Leem
M J
MJ
Shin
D H
DH
Chang
H B
HB
Hong
S W
SW
Moon
E Y
EY
Lee
D K
DK
Yoon
S J
SJ
Woo
W S
WS
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal / Q000737:chemistry*; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic