title: Isolated oculomotor nerve palsy: an unusual presentation of glioblastoma multiforme. Case report and review of the literature.
abstract: The authors present a case of a very unusual clinical presentation of an intra-axial supratentorial glioblastoma multiforme (GBM) in a 63 year old diabetic female patient presenting with a three week history of left progressive complete oculomotor nerve palsy. CT scan and magnetic resonance imaging of the head revealed a left intra-axial mesial temporal glioblastoma multiforme. Operative resection and microscopic examination of a tissue specimen confirmed the diagnosis. The nature of the tumor, the pattern of spread and the postulated mechanisms of such a presentation are discussed. The authors suggest including the diagnosis of GBM in the differential diagnosis of patients with isolated complete oculomotor nerve palsy at the appropriate age group.
authors.affiliation: Division of Neurosurgery, Toronto Hospital Western, Ontario, Canada.
authors.forename: M
authors.initials: M
authors.lastname: al-Yamany
authors.forename: A
authors.initials: A
authors.lastname: al-Shayji
authors.forename: M
authors.initials: M
authors.lastname: Bernstein
mesh_terms: D005260:Female; D005909:Glioblastoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D015840:Oculomotor Nerve Diseases / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D015173:Supratentorial Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery