title: Does avascular necrosis cause collapse of the dome of the talus in severe haemophilia?
abstract: Arthropathy of the ankle joint is commonly observed in people with severe haemophilia. A review of the radiological appearance of ankle arthropathy provides evidence that the changes in the talar bone of the ankle joint are probably due to avascular necrosis. This may arise due to impairment to the arterial supply, as it enters the talar neck, secondary to the increased pressure at the time of haemarthroses.
authors.affiliation: Princess Margaret Rose Orthopaedic Hospital, Edinburgh, UK.
authors.forename: M F
authors.initials: MF
authors.lastname: MacNicol
authors.forename: C A
authors.initials: CA
authors.lastname: Ludlam
mesh_terms: D006467:Hemophilia A / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D010020:Osteonecrosis / Q000150:complications*; D013628:Talus / Q000473:pathology*