In vitro adhesion and platelet aggregation properties of bacteremia-associated lactobacilli.
Eight bacteremia-associated Lactobacillus strains were evaluated in vitro for the ability to adhere to human intestinal mucosa and to aggregate platelets. Adherence varied significantly among the strains, and platelet aggregation was induced by three strains. In conclusion, strong binding ability does not appear to be a prerequisite for the involvement of lactobacilli in bacteremia or to their ability to aggregate platelets.
Kirjavainen
P V
PV
Department of Biochemistry and Food Chemistry, University of Turku, Turku, Finland. pirkka.kirjavainen@utu.fi
Tuomola
E M
EM
Crittenden
R G
RG
Ouwehand
A C
AC
Harty
D W
DW
Morris
L F
LF
Rautelin
H
H
Playne
M J
MJ
Donohue
D C
DC
Salminen
S J
SJ
D016470:Bacteremia / Q000097:blood / Q000209:etiology* / Q000382:microbiology; D001422:Bacterial Adhesion / Q000502:physiology*; D018938:Caco-2 Cells; D016908:Gram-Positive Bacterial Infections / Q000097:blood / Q000209:etiology* / Q000382:microbiology; D006801:Humans; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000382:microbiology; D007778:Lactobacillus / Q000235:genetics / Q000472:pathogenicity* / Q000502:physiology*; D009093:Mucus / Q000382:microbiology; D010974:Platelet Aggregation / Q000502:physiology*; D013045:Species Specificity; D014774:Virulence