title: [Computed tomography with normal chest radiography in childhood tuberculosis].
abstract: During the recent 2 years we experienced 5 children (2 months-5 years old) with lung tuberculosis, all of whom had positive tuberculin skin-tests, and were in close contact with their family members who had active tuberculosis. However, no abnormal findings on chest X-ray films were pointed out by 2 independent roentogenologists, and no increased levels of inflammatory markers including WBC numbers, CRP, and ESR were detected in all but one child. Moreover, mycobacterial examination of sputa and/or gastric aspirates by microscope, culture technique, and PCR amplification revealed no causative bacilli in 4 children. To clarify whether these children were affected by Mycobacterium tuberculosis, chest CT scan was applied. Surprisingly, all 5 children were revealed to have abnormal changes including primary complexes in the lung field. Taken together, it is important to pursuit the apparent lung tuberculosis in children with a positive family history and positive tuberculin skin-test.
authors.affiliation: Department of Pediatrics, Yokohama City University School of Medicine.
authors.forename: S
authors.initials: S
authors.lastname: Katakura
authors.forename: T
authors.initials: T
authors.lastname: Imagawa
authors.forename: S
authors.initials: S
authors.lastname: Ito
authors.forename: T
authors.initials: T
authors.lastname: Miyamae
authors.forename: T
authors.initials: T
authors.lastname: Mitsuda
authors.forename: M
authors.initials: M
authors.lastname: Ibe
authors.forename: Y
authors.initials: Y
authors.lastname: Aihara
authors.forename: S
authors.initials: S
authors.lastname: Yokota
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging*