The inactivation of single-chain urokinase-type plasminogen activator by thrombin may provide an additional explanation for the antifibrinolytic effect of factor XI.
Braat
E A
EA
Rijken
D C
DC
D000933:Antifibrinolytic Agents / Q000494:pharmacology*; D004789:Enzyme Activation / Q000187:drug effects; D005172:Factor XI / Q000494:pharmacology*; D006801:Humans; D015849:Plasminogen Inactivators / Q000494:pharmacology; D013917:Thrombin / Q000494:pharmacology*; D014568:Urokinase-Type Plasminogen Activator / Q000378:metabolism*
D000933:Antifibrinolytic Agents; D015849:Plasminogen Inactivators; D005172:Factor XI; D013917:Thrombin; D014568:Urokinase-Type Plasminogen Activator