title: [Multilocular vegetating pyoderma gangrenosum].
abstract: Vegetative pyoderma gangrenosum is a nonaggressive, chronic, superficial variant of pyoderma gangrenosum. Unlike classic ulcerative pyoderma gangrenosum, the lesions are less deep and not painful, and the borders are not undermined. The base of ulcers usually shows granulation tissue. The histopathologic findings are characterized by superficial granulomas. Cultures for fungal or bacterial infections normally are negative. Vegetative pyoderma gangrenosum is seldom associated with systemic diseases and often responds to simple modes of therapy. Our patient had a 10 years history of superficial ulcers on face, trunk and upper arms, whose general health was not impaired. A broad diagnostical evaluation showed no systemic diseases. The histologic pattern demonstrated a granulomatous dermatitis. After exclusion of other causes, we believe the patient has the vegetative form of pyoderma gangraenosum. There was no improvement with local treatment. Only systemic therapy with corticosteroids and later on cyclosporine led to healing.
authors.affiliation: Dermatologische Abteilung, Krankenhauses Spandau, Berlin.
authors.forename: T
authors.initials: T
authors.lastname: Wildfeuer
authors.forename: G
authors.initials: G
authors.lastname: Albrecht
mesh_terms: D000328:Adult; D001706:Biopsy; D002908:Chronic Disease; D003937:Diagnosis, Differential; D006097:Granulation Tissue / Q000473:pathology; D006801:Humans; D008297:Male; D017511:Pyoderma Gangrenosum / Q000473:pathology*; D012867:Skin / Q000473:pathology