title: Clinical practice guidelines for the use of albumin: results of a drug use evaluation in a Paris hospital. Tenon Hospital Paris.
abstract: Clinical practice guidelines on the prescription of albumin were instituted in our hospital according to a method which combined a review of the medical literature with experts points of view. Their broadcasting was based upon a daily patient-specific decision support which was well-documented by the prescribing physician. The method for assessing the impact was a six month analysis of the discrepancies between recommendations and clinical practice. Results were a better compliance with guidelines (25.5% before and 59% after developing recommendations), a decrease 70% in grams of albumin prescribed and in use of an increase synthetic colloids, and a savings of $57,208 per year.
authors.affiliation: Department of Pharmacy and Toxicology, Local Drug Committee-Tenon Hospital, Paris, France.
authors.forename: I
authors.initials: I
authors.lastname: Debrix
authors.forename: D
authors.initials: D
authors.lastname: Combeau
authors.forename: F
authors.initials: F
authors.lastname: Stephan
authors.forename: A
authors.initials: A
authors.lastname: Benomar
authors.forename: A
authors.initials: A
authors.lastname: Becker
mesh_terms: D001810:Blood Volume / Q000187:drug effects / Q000502:physiology; D002056:Burns / Q000628:therapy; D004363:Drug Utilization; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000628:therapy; D010606:Pharmacy and Therapeutics Committee; D010951:Plasma Exchange; D010952:Plasma Substitutes / Q000008:administration & dosage / Q000627:therapeutic use; D011183:Postoperative Complications / Q000628:therapy; D011247:Pregnancy; D012709:Serum Albumin / Q000008:administration & dosage / Q000627:therapeutic use*; D012769:Shock / Q000503:physiopathology / Q000628:therapy
chemical_list: D010952:Plasma Substitutes; D012709:Serum Albumin