title: Lack of effect of combined low intensity laser therapy/phototherapy (CLILT) on delayed onset muscle soreness in humans.
abstract: OBJECTIVE
  This study, which was approved by the University's Ethical committee, was conducted to investigate the effectiveness of Combined Low Intensity Laser Therapy/Phototherapy (CLILT) in alleviating the signs and symptoms of Delayed Onset Muscle Soreness (DOMS) over an 11-day period.
  
  
  METHODS
  Thirty-six subjects (18 M: 18 F) were randomly allocated, under strictly controlled double-blind conditions, to one of three experimental conditions: Control, Placebo, and CLILT (660-950 nm; 11 J/cm2; pulsed at 73 Hz). DOMS was induced in a standardised fashion in the non-dominant elbow flexors using repeated eccentric contractions until exhaustion was reached. Subjects returned on five consecutive days, and two days during the following week, for treatment according to group, and assessment of outcome variables including range of motion, pain, and tenderness.
  
  
  RESULTS
  While analysis of results using repeated measures and one factor ANOVA with post-hoc tests showed significant changes in all variables over time (P < 0.05) as a result of the induction procedure, there were no significant differences observed between groups.
  
  
  CONCLUSIONS
  CLILT failed to show any beneficial treatment effect on DOMS, at least at the parameters used here. These results therefore provide no evidence for the claimed biostimulating effects of such therapy.
authors.affiliation: Rehabilitation Sciences Research Group, School of Health Sciences, University of Ulster, Northern Ireland, United Kingdom. ja.craig@ulst.ac.uk
authors.forename: J A
authors.initials: JA
authors.lastname: Craig
authors.forename: J
authors.initials: J
authors.lastname: Barron
authors.forename: D M
authors.initials: DM
authors.lastname: Walsh
authors.forename: G D
authors.initials: GD
authors.lastname: Baxter
mesh_terms: D000328:Adult; D004311:Double-Blind Method; D004550:Elbow / Q000503:physiopathology; D015444:Exercise / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D008297:Male; D018763:Muscle Fatigue; D009135:Muscular Diseases / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D010146:Pain / Q000209:etiology / Q000503:physiopathology; D059408:Pain Management; D010147:Pain Measurement; D017288:Pain Threshold; D010789:Phototherapy; D016059:Range of Motion, Articular; D011795:Surveys and Questionnaires; D016896:Treatment Outcome