title: Isolated renal Aspergillus abscess in an AIDS patient with a normal CD4+ cell count on highly active antiretroviral therapy.
abstract: Isolated renal Aspergillus abscess is a very rare complication of HIV infection. It usually occurs in patients with severe immune deficiency. The case of a 29-year-old HIV-infected homosexual male, a nonintravenous drug abuser, who developed a right renal Aspergillus abscess despite normalization of the CD4+ cell count after highly active antiretroviral treatment is described. When antimicrobial treatment failed (amphotericin B followed by itraconazole), he was cured by right nephrectomy and remains in good health 3 months later with no recurrence. In cases of Aspergillus renal abscess in HIV-infected patients, surgery is the treatment of choice, especially in the current era of highly active antiretroviral therapy.
authors.affiliation: Centre d'Informations et de Soins de l'Immunodéficience Humaine, Clinique Médicale A, Hôpitaux Universitaires, Strasbourg, France. david.rey@chru-strasbourg.fr
authors.forename: D
authors.initials: D
authors.lastname: Rey
authors.forename: E
authors.initials: E
authors.lastname: de Mautort
authors.forename: C
authors.initials: C
authors.lastname: Saussine
authors.forename: Y
authors.initials: Y
authors.lastname: Hansmann
authors.forename: J
authors.initials: J
authors.lastname: Waller
authors.forename: R
authors.initials: R
authors.lastname: Herbrecht
authors.forename: D
authors.initials: D
authors.lastname: Christmann
authors.forename: V
authors.initials: V
authors.lastname: Lindner
authors.forename: V
authors.initials: V
authors.lastname: Letscher-Bru
authors.forename: H
authors.initials: H
authors.lastname: Koenig
authors.forename: J M
authors.initials: JM
authors.lastname: Lang
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology* / Q000601:surgery; D000038:Abscess / Q000382:microbiology* / Q000601:surgery; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000382:microbiology*; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D018791:CD4 Lymphocyte Count; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007674:Kidney Diseases / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D008297:Male
chemical_list: D019380:Anti-HIV Agents