title: Expression of glutamate transporters in the adult bovine corpus callosum.
abstract: The presence and distribution of the glutamate transporters, EAAC1, GLAST and GLT-1, were examined in the adult bovine corpus callosum by means of Western blotting and immunohistochemistry. We found GLAST to be expressed in oligodendrocytes and in some astrocytes. GLT-1 was located throughout the processes of fibrous astrocytes. In addition, EAAC1 was present in a small population of cells that are probably adult oligodendrocyte progenitor cells.
authors.affiliation: Departamento de Neurociencias, Facultad de Medicina y Odontología, Universidad del País Vasco, 48940 Leioa, Vizcaya, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Domercq
authors.forename: C
authors.initials: C
authors.lastname: Matute
mesh_terms: D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases / Q000032:analysis; D018528:ATP-Binding Cassette Transporters / Q000032:analysis / Q000235:genetics / Q000378:metabolism; D000367:Age Factors; D027322:Amino Acid Transport System X-AG; D000818:Animals; D001253:Astrocytes / Q000737:chemistry / Q000378:metabolism; D015153:Blotting, Western; D002352:Carrier Proteins / Q000032:analysis / Q000235:genetics* / Q000378:metabolism; D002417:Cattle; D048429:Cell Size / Q000502:physiology; D003337:Corpus Callosum / Q000737:chemistry* / Q000166:cytology / Q000378:metabolism; D005455:Fluorescent Antibody Technique; D015870:Gene Expression / Q000502:physiology; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D050491:Glutamate Plasma Membrane Transport Proteins; D018698:Glutamic Acid / Q000378:metabolism*; D006706:Homeostasis / Q000235:genetics; D007381:Intermediate Filament Proteins / Q000032:analysis; D009419:Nerve Tissue Proteins; D064231:Nestin; D009474:Neurons / Q000737:chemistry / Q000166:cytology; D009836:Oligodendroglia / Q000737:chemistry / Q000201:enzymology; D013234:Stem Cells / Q000737:chemistry / Q000201:enzymology; D027981:Symporters
chemical_list: D018528:ATP-Binding Cassette Transporters; D027322:Amino Acid Transport System X-AG; D002352:Carrier Proteins; D005904:Glial Fibrillary Acidic Protein; D050491:Glutamate Plasma Membrane Transport Proteins; D007381:Intermediate Filament Proteins; D009419:Nerve Tissue Proteins; D064231:Nestin; D027981:Symporters; D018698:Glutamic Acid; D015087:2',3'-Cyclic-Nucleotide Phosphodiesterases