title: Pediatric bacterial endocarditis. Treatment and prophylaxis.
abstract: Endocarditis is a rare but serious complication often related to complex CHD. The incidence, particularly among smaller infants with cyanotic heart disease, seems to be increasing. The pathophysiology is related to a combination of host and bacterial factors that predispose to endothelial colonization and infection. Diagnosis, although occasionally difficult, is life saving, but the treatment is prolonged. Prophylaxis before appropriate procedures may significantly decrease the risk for development in appropriate patients.
authors.affiliation: Department of Pediatrics, University of California-San Francisco, USA.
authors.forename: M M
authors.initials: MM
authors.lastname: Brook
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis; D015984:Causality; D002648:Child; D002675:Child, Preschool; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008826:Microbial Sensitivity Tests; D018579:Patient Selection
chemical_list: D000900:Anti-Bacterial Agents