Paraneoplastic opsoclonus-myoclonus secondary to malignant melanoma.
Opsoclonus-myoclonus is a well-described paraneoplastic syndrome that most often occurs in association with small cell carcinoma of the lung and breast carcinoma. To the best of our knowledge, we describe the first reported case of paraneoplastic opsoclonus-myoclonus occurring is association with malignant melanoma. Antineuronal antibodies were not identified despite repeated testing. No therapeutic benefit was observed following corticosteroid administration.
Berger
J R
JR
Department of Neurology, University of Kentucky College of Medicine, Lexington, USA. jrbneuro@pop.uky.edu
Mehari
E
E
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000150:complications* / Q000473:pathology; D009207:Myoclonus / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D015835:Ocular Motility Disorders / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D010257:Paraneoplastic Syndromes / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D011241:Prednisone / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D011241:Prednisone