title: [Kaposiform HHV-8 negative acroangiodermatitis in chronic venous insufficiency].
abstract: A 76-year-old female patient developed severe manifestations of a kaposi-like acroangiodermatitis (so-called Mali's disease) due to chronic venous insufficiency of the lower extremities. The patient presented with large areas of confluent, violaceous or brown-black papules on both lower legs. Histologically, proliferation of thick-walled capillaries was seen in the upper dermis consisting of fully differentiated endothelial cells, as shown by immunohistochemistry. In contrast to true Kaposi's sarcoma, human-herpes-virus-8 DNA could not be detected by polymerase-chain-reaction in this condition. We review the diagnostic criteria used to distinguish between acroangiodermatitis, also called pseudo-Kaposi's sarcoma, and the true Kaposi's sarcoma.
authors.affiliation: Hautklinik und Poliklinik, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin.
authors.forename: S
authors.initials: S
authors.lastname: Krengel
authors.forename: S
authors.initials: S
authors.lastname: Goerdt
authors.forename: K
authors.initials: K
authors.lastname: Krüger
authors.forename: P
authors.initials: P
authors.lastname: Schnitzler
authors.forename: M
authors.initials: M
authors.lastname: Geiss
authors.forename: B
authors.initials: B
authors.lastname: Tebbe
authors.forename: U
authors.initials: U
authors.lastname: Blume-Peytavi
authors.forename: C E
authors.initials: CE
authors.lastname: Orfanos
mesh_terms: D000169:Acrodermatitis / Q000473:pathology*; D000368:Aged; D002196:Capillaries / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D019288:Herpesvirus 8, Human / Q000302:isolation & purification; D006801:Humans; D012514:Sarcoma, Kaposi / Q000473:pathology*; D012867:Skin / Q000098:blood supply / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*; D014657:Vasculitis / Q000473:pathology*; D014689:Venous Insufficiency / Q000473:pathology*