title: [Carcinoma of the nasopharynx, radiotherapy, otitis, labyrinthitis, inflammation of the petrous bone, meningitis].
abstract: Endocranial complications of otitis show new etiopathogenic possibilities. We have accomplished an analysis of this issue after one of these cases. A female patient with a nasopharyngeal carcinoma developed an otogenous meningitis. Radiotherapeutic management was followed by osteoradionecrosis of cranial basis, local hypoimmunity favorized the reported course: middle otitis, labyrinthitis, petrositis and meningitis. Comments on pathogenetic, clinic and therapeutical peculiarities of this case.
authors.affiliation: Cátedra de Orl, Hospital Universitario Pío del Río Ortega, Valladolid, España.
authors.forename: P
authors.initials: P
authors.lastname: Pomar Blanco
authors.forename: I
authors.initials: I
authors.lastname: Díaz Suárez
authors.forename: L M
authors.initials: LM
authors.lastname: Gil-Carcedo
authors.forename: L A
authors.initials: LA
authors.lastname: Vallejo Valdezate
mesh_terms: D000368:Aged; D001847:Bone Diseases; D002277:Carcinoma / Q000150:complications* / Q000175:diagnosis / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007762:Labyrinthitis / Q000175:diagnosis / Q000209:etiology*; D016920:Meningitis, Bacterial / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D009303:Nasopharyngeal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000532:radiotherapy*; D009336:Necrosis; D010025:Osteoradionecrosis; D010035:Otitis Media, Suppurative / Q000150:complications* / Q000175:diagnosis*; D010579:Petrous Bone / Q000473:pathology*; D013290:Streptococcal Infections / Q000382:microbiology; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed; D018058:Tympanic Membrane Perforation / Q000209:etiology