Oxidation products of zeylanidine
The oxidation of zeylanidine (1) afforded two new sesquiterpene dilactones, 4 and 5, besides two known compounds, neoliacine (2) and zeylanidinone (3). The structures of the novel oxidized products were elucidated on the basis of spectroscopic techniques, and the structure of compound 5 was further confirmed by X-ray crystallographic analysis. The mechanism for the oxidation of 1 to 4 and 5 has been postulated.
Chen
KS
Ta-Jen Pharmaceutical Junior College, Ping Tung Hsien 907, Taiwan, Graduate Institute of Natural Products, Kaohsiung Medical College, Kaohsiung 807, Taiwan, and Department of Chemistry, National Sun Yat-Sen University, Kaohsiung 807, Taiwan.
Chang
FR
Chiang
MY
Wu
YC