title: Experimental treatment with sodium stibogluconate of hamsters infected with Leishmania (Leishmania) chagasi and Leishmania (Leishmania) amazonensis.
abstract: The present paper reports the experimental treatment of hamsters infected with Leishmania chagasi and Leishmania amazonensis with sodium stibogluconate (20 mg/kg/day x 20 days). Only with L. chagasi did the treatment result in the complete elimination of parasites from the spleen. However, no parasitological cure was achieved in hamsters infected with L. amazonensis.
authors.affiliation: Laboratório de Leishmanioses, Centro de Pesquisas René Rachou/FIOCRUZ, Fundação Nacional de Saúde, Belo Horizonte, MG, Brasil.
authors.forename: E M
authors.initials: EM
authors.lastname: de Figueiredo
authors.forename: J
authors.initials: J
authors.lastname: Costa e Silva
authors.forename: R P
authors.initials: RP
authors.lastname: Brazil
mesh_terms: D000818:Animals; D000967:Antimony Sodium Gluconate / Q000627:therapeutic use*; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D006224:Cricetinae; D004353:Drug Evaluation, Preclinical; D018314:Leishmania infantum; D007894:Leishmania mexicana; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy*; D007898:Leishmaniasis, Visceral / Q000188:drug therapy*; D008297:Male; D008647:Mesocricetus; D013997:Time Factors
chemical_list: D000981:Antiprotozoal Agents; D000967:Antimony Sodium Gluconate