title: Homologation of alpha-amino acids to beta-amino acids using Fmoc-amino acid pentafluorophenyl esters.
abstract: The homologation of alpha-amino acids to beta-amino acids by the two-step Arndt-Eister method is achieved by using Fmoc-alpha-amino acid pentafluorophenyl esters for the acylation of diazomethane, synthesizing the key intermediates Fmoc-aminoacyldiazomethanes as crystalline solids in good yields and purity.
authors.affiliation: Department of Studies in Chemistry, Central College Campus, Bangalore University, India.
authors.forename: V V
authors.initials: VV
authors.lastname: Babu
authors.forename: H N
authors.initials: HN
authors.lastname: Gopi
authors.forename: K
authors.initials: K
authors.lastname: Ananda
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis*; D003978:Diazomethane / Q000737:chemistry; D004952:Esters / Q000737:chemistry*; D008956:Models, Chemical
chemical_list: D000596:Amino Acids; D004952:Esters; D003978:Diazomethane