Attempts to identify herpes simplex virus DNA in normal and diseased human peripheral nerve.
PCR analysis of DNA extracted from 31 sections of formalin-fixed sural nerve biopsies did not reveal herpes simplex virus (HSV) DNA. Unlike the presence of HSV DNA sequences in normal human brain, spinal cord, and ganglia, HSV DNA is not present in normal or diseased human distal peripheral nerve.
Sze
C I
CI
Department of Pathology, University of Colorado Health Sciences Center, Denver 80262, USA.
Mahalingam
R
R
Wellish
M
M
Levy
A S
AS
Wu
E
E
Pfister
S J
SJ
Gilden
D H
DH
Kleinschmidt-DeMasters
B K
BK
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010525:Peripheral Nerves / Q000737:chemistry*; D010523:Peripheral Nervous System Diseases / Q000378:metabolism*; D018139:Simplexvirus / Q000235:genetics*
D004279:DNA, Viral