title: Protecting the "animal of necessity": limits to inquiry in clinical investigation.
authors.forename: J P
authors.initials: JP
authors.lastname: Swazey
mesh_terms: D003256:Community Participation; D004992:Ethics, Medical; D006805:Human Experimentation; D006801:Humans; D007878:Legislation as Topic; D008511:Medicine; D009316:National Institutes of Health (U.S.); D012106:Research; D014481:United States; D014486:United States Food and Drug Administration