[Effect of renitek--an ACE inhibitor--versus cozaar--an angiotensin I receptors antagonists--on morphofunctional state of left ventricular myocardium in patients with symptomatic cardiac insufficiency].
128 patients treated by renitek or cozaar for ischemic heart disease of NYHA class II-III effort angina and circulation insufficiency were subjected to echocardiographic monitoring for 12 weeks. Both drugs have proved their effectiveness in relation to prevention and inhibition of progression of pathological remodelling of the myocardium. Renitek is superior to cozaar in improving total contractility and morphofunctional state of the left ventricular myocardium. Cozaar is more effective than renitek in improvement of left ventricular local contraction and relaxation.
Vizir
V A
VA
Berezin
A E
AE
D000328:Adult; D000368:Aged; D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D004452:Echocardiography; D004656:Enalapril / Q000627:therapeutic use*; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000503:physiopathology; D006801:Humans; D019808:Losartan / Q000627:therapeutic use*; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D016896:Treatment Outcome
D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000889:Anti-Arrhythmia Agents; D004656:Enalapril; D019808:Losartan