title: A randomized, double-blind, placebo-controlled study of methylphenidate in patients with organic amnesia.
abstract: We examined the usefulness of methylphenidate (MPH) in the treatment of organic amnesia in a randomized, double-blind, placebo-controlled design. Twenty patients with amnesia due to closed head injuries (n = 10), viral encephalitis (n = 2), stroke lesions (n = 4), or surgical brain resections (n = 4) were assessed with a neuropsychological battery after the intake of MPH (10, 20, 30 or 40 mg), or placebo. We found no significant benefit of MPH for any of the cognitive tests.Copyright Lippincott-Raven Publishers
authors.affiliation: Department of Neuropsychiatry, RaGl Carrea Institute of Neurological Research, Buenos Aires, Argentina.
authors.initials: C
authors.lastname: Tiberti
authors.initials: L
authors.lastname: Sabe
authors.initials: L
authors.lastname: Jason
authors.initials: R
authors.lastname: Leiguarda
authors.initials: S
authors.lastname: Starkstein