Systemic lupus erythematosus presenting with steroid-responsive parkinsonism and post-hemiplegic dystonia.
A young male patient who presented with steroid-responsive parkinsonism, hemiplegia, thrombocytopaenia and systemic illness who was subsequently diagnosed to have systemic lupus erythematosus (SLE) is described. He later developed post-hemiplegic dystonia. Thalamic lesions on magnetic resonance imaging (MRI) are demonstrated. Clinical features and neuropathology of central nervous system lupus are discussed. This is the first report of SLE presenting with Parkinsonism, and the first to demonstrate anatomically-relevant MRI lesions in Parkinsonism associated with SLE.Copyright Lippincott-Raven Publishers
Lim
SM
Department of Neurology, Leicester Royal Infirmary, Leicester, UK.
Oldfield
M
Abbott
RJ