[The influence of bromocriptine treatment on prolactin secretion in infertile women with suspicion of luteal phase insufficiency].
There were 30 infertile women with insufficient luteal phase of the cycle under the study. The hyperprolactinemia was diagnosed in 14 from 30 infertile women. In women with normal cycles the ovulation occurred in 18 day of the cycle. During the treatment with Bromocorn it was observed earlier, independently from the prolactin level in blood serum. The luteal phase of the cycle in controls lasted for 9.9 +/- 0.2 days and 11.8 +/- 0.5 days in women after one cycle with Bromocorn and 12.3 +/- 0.2 days after two cycles with Bromocorn. Duration of the cycles in these three studied groups differed statistically significantly (p < 0.001). In women treated with Bromocorn the second cycle phase lasted longer than 11 day and the differences in progesterone and LH levels in the middle of the cycle and at the end of the luteal phase were insignificant. The obtained results show, that Bromocorn could be a suitable method of treatment in the luteal phase insufficiency.
Krzemiński
A
A
Kliniki Ginekologii II Katedry Połoznictwa i Chorób Kobiecych Akademii Medycznej w Lublinie.
Sikorski
R
R
Woźniak
S
S
D000328:Adult; D001971:Bromocriptine / Q000494:pharmacology* / Q000627:therapeutic use*; D005260:Female; D006727:Hormone Antagonists / Q000494:pharmacology* / Q000627:therapeutic use*; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy*; D008183:Luteal Phase / Q000187:drug effects*; D011388:Prolactin / Q000097:blood / Q000378:metabolism*
D006727:Hormone Antagonists; D001971:Bromocriptine; D011388:Prolactin