title: Management of pleural effusions in children with malignant lymphoma.
abstract: OBJECTIVE
  The aim of this study was to determine potential problems in the diagnosis and management of children with pleural effusions and malignant lymphoma as well as the efficacy of thoracentesis.
  
  
  METHODS
  The case histories of six children with malignant lymphoma who presented with pleural effusions were reviewed. Thoracentesis was performed using the Seldinger technique.
  
  
  RESULTS
  Four of the children presented with symptoms and chest radiograph findings similar to pneumonia. A large mediastinal mass was present in two children. Pleural fluid analysis resulted in a definitive diagnosis of lymphoma in five of the six children. Two of the children had symptoms of reexpansion pulmonary edema after removal of pleural fluid. An empyema developed in one child after thoracotomy and chest tube placement. Reaccumulation of pleural fluid was common before initiating chemotherapy.
  
  
  CONCLUSIONS
  Malignant pleural effusions frequently are present in children with non-Hodgkin's lymphoma. They may present with respiratory distress because of the size of the effusion, the mediastinal mass, or both. Management of these pleural effusions is associated with potential complications, some of which are life threatening. Thoracentesis is the initial diagnostic and therapeutic procedure of choice. The use of a Seldinger technique for thoracentesis has proved useful and safe. In patients with large effusions, aggressive removal of the pleural fluid may be followed by reexpansion pulmonary edema.
authors.affiliation: Department of Pediatric Surgery, Vanderbilt Children's Hospital, Nashville, TN, USA.
authors.forename: J B
authors.initials: JB
authors.lastname: Pietsch
authors.forename: J A
authors.initials: JA
authors.lastname: Whitlock
authors.forename: C
authors.initials: C
authors.lastname: Ford
authors.forename: M C
authors.initials: MC
authors.lastname: Kinney
mesh_terms: D000293:Adolescent; D015505:Chest Tubes; D002648:Child; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D008297:Male; D016066:Pleural Effusion, Malignant / Q000209:etiology / Q000628:therapy*