Predictors of neurological morbidity after coronary artery bypass surgery.
OBJECTIVE
The aim of this study was to analyze the postoperative neurological complications after myocardial revascularization.


METHODS
We analyzed the pre-, peri- and postoperative data of 3834 patients who underwent a primary isolated bypass grafting between January 1987 and December 1995. Postoperative neurological complications (A) were divided into mild complications (B) and major complications (C).


RESULTS
The incidence of A increased, from 1.4% to 3.0%. Unifactor risk analysis identified: age > 75 years, peripheral vascular atherosclerosis, neurological pathology, aorta-pathology and perioperative myocardial infarction as risk factors for A. Perioperative myocardial infarction and neurological pathology for B; age > 75 years, peripheral vascular atherosclerosis, neurological pathology, perioperative myocardial infarction and aorta pathology for C. Multifactor risk regression analysis identified peripheral vascular atherosclerosis, neurological pathology, aorta-pathology, perioperative myocardial infarction and the time cohort 1993-1995 as independent predictors for A; perioperative myocardial infarction and the time cohort 1993-1995 for B; neurological pathology, aorta-pathology and perioperative myocardial infarction for C.


CONCLUSIONS
Peripheral vascular atherosclerosis, neurological pathology, aorta-pathology, the occurrence of a perioperative myocardial infarction and the time cohort 1993-1995 are identified as independent risk factors for neurological complications.
Janssen
D P
DP
Department of Thoracic and Cardiac Surgery 414, University Hospital Nijmegen, The Netherlands.
Noyez
L
L
van Druten
J A
JA
Skotnicki
S H
SH
Lacquet
L K
LK
D000368:Aged; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D017202:Myocardial Ischemia / Q000601:surgery*; D009422:Nervous System Diseases / Q000175:diagnosis / Q000209:etiology*; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors