title: Allogeneic bone marrow transplantation for advanced Waldenstrom's macroglobulinemia.
abstract: Waldenstrom's disease is a lymphoproliferative disorder that is typically treated with plasmapheresis and/or alkylating agents. In young patients, other lymphoproliferative disorders have been treated with allogeneic transplantation. Two patients with aggressive Waldenstrom's disease, who progressed in spite of multi-agent chemotherapy and autologous stem cell transplantation, in one case, underwent allogeneic transplantation from their HLA-identical donors. Both remain alive with event-free survivals of more than 3, and more than 9 years, respectively. Allogeneic transplantation should be considered for young patients with Waldenstrom's disease.
authors.affiliation: Clinical Hematology Division, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Martino
authors.forename: A
authors.initials: A
authors.lastname: Shah
authors.forename: P
authors.initials: P
authors.lastname: Romero
authors.forename: S
authors.initials: S
authors.lastname: Brunet
authors.forename: J
authors.initials: J
authors.lastname: Sierra
authors.forename: A
authors.initials: A
authors.lastname: Domingo-Albós
authors.forename: S
authors.initials: S
authors.lastname: Fruchtman
authors.forename: L
authors.initials: L
authors.lastname: Isola
mesh_terms: D000328:Adult; D016026:Bone Marrow Transplantation; D005260:Female; D006801:Humans; D008297:Male; D014184:Transplantation, Homologous; D008258:Waldenstrom Macroglobulinemia / Q000628:therapy*