title: Mitral valve repair for isolated prolapse of the anterior leaflet: an 11-year follow-up.
abstract: OBJECTIVE
  Mitral valve insufficiency (MVI) because of involvement of the anterior mitral leaflet may pose additional risks for late outcome after mitral valve repair, because of more complex techniques. We retrospectively reviewed our experience in patients operated on for isolated anterior mitral leaflet prolapse approached by various techniques.
  
  
  METHODS
  Between 1986 and 1997, 616 patients underwent mitral valve repair at our Institution. Isolated pathology of the anterior mitral leaflet was the cause of MVI in 84 patients (13.6%). Age ranged from 23 to 74 years (mean 50 +/- 14). Etiology of MVI was predominantly degenerative (57 patients, 67.8%), and the mechanism of the regurgitation was mainly due to a chordal rupture (58 patients, 69%). Annular dilatation was present in 75 patients (89.5%). A variety of surgical techniques were applied including chordal shortening (five patients, 5.9%), chordal transposition (three patients, 3.5%), artificial chordae (11 patients, 13%). Since 1992, however, the majority of procedures was performed using the 'edge to edge' technique (52 patients, 51.9%). Annular dilatation was treated mainly by means of a prosthetic ring (46 patients, 61.3%) whereas 18 patients (24%) underwent posterior annuloplasty using gluteraldehyde-treated native pericardium.
  
  
  RESULTS
  Follow-up ranged from 3 to 122 months (mean 46 +/- 24 months). There were three hospital deaths (3.5%) and five late deaths (5.9%) for a Kaplan-Meier estimated survival of 87.6% at 8 years. Three patients underwent early reoperation within 30 days (3.5%), and six patients underwent late reoperation (7.1%), for a cumulative freedom from reoperation of 85.4% at 8 years. Seventy-four percent of the survivors (50 patients) are still in New York Heart Association Class I, and 92% of survivors (62 patients) have no or trivial (1+) residual mitral regurgitation at echocardiographic follow-up.
  
  
  CONCLUSIONS
  In spite of the greater complexity, conservative surgery to correct anterior mitral valve prolapse pertains high success rate of long term. Recent technical modifications ('edge-to-edge' technique) may allow more expeditious and reproducible procedures with expected favorable influence of mitral valve repair applicability.
authors.affiliation: 2nd Division of Cardiac Surgery, Civic Hospital, Brescia, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Totaro
authors.forename: E
authors.initials: E
authors.lastname: Tulumello
authors.forename: P
authors.initials: P
authors.lastname: Fellini
authors.forename: M
authors.initials: M
authors.lastname: Rambaldini
authors.forename: G
authors.initials: G
authors.lastname: La Canna
authors.forename: G
authors.initials: G
authors.lastname: Coletti
authors.forename: M
authors.initials: M
authors.lastname: Zogno
authors.forename: R
authors.initials: R
authors.lastname: Lorusso
mesh_terms: D006348:Cardiac Surgical Procedures; D017548:Echocardiography, Transesophageal; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D008945:Mitral Valve Prolapse / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D012086:Reoperation; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome