Mycobacterium sp. as a possible cause of hypersensitivity pneumonitis in machine workers.
Hypersensitivity pneumonitis (HP) in workers exposed to metal removal fluids (MRFs) is increasing. This study supports the hypothesis that aerosolized mycobacteria colonizing the MRFs likely cause the disease. Three case studies of HP outbreaks among metal workers showed potentially high exposures to a rare and newly proposed Mycobacterium species. Retrospective review of samples submitted to our laboratory showed an association between presence of mycobacteria and HP.
Shelton
B G
BG
PathCon Laboratories, Norcross, Georgia 30092, USA. bshelton@pathcon.com
Flanders
W D
WD
Morris
G K
GK
D000542:Alveolitis, Extrinsic Allergic / Q000209:etiology*; D000907:Antibodies, Bacterial / Q000097:blood; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008670:Metals; D008875:Middle Aged; D009161:Mycobacterium / Q000276:immunology / Q000302:isolation & purification*; D009784:Occupational Diseases / Q000209:etiology*
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D008670:Metals