title: Bacterial invasion: Force feeding by Salmonella.
abstract: Recent findings have shed new light on mammalian-cell invasion by Salmonella. Using a type III secretion system, Salmonella deliver virulence factors into the host cell that directly activate signal transduction pathways, initiating cytoskeletal rearrangements and bacterial uptake by a ruffling mechanism.
authors.affiliation: Biotechnology Laboratory, University of British Columbia, Vancouver, Canada.
authors.forename: J H
authors.initials: JH
authors.lastname: Brumell
authors.forename: O
authors.initials: O
authors.lastname: Steele-Mortimer
authors.forename: B B
authors.initials: BB
authors.lastname: Finlay
mesh_terms: D000818:Animals; D001424:Bacterial Infections / Q000378:metabolism / Q000503:physiopathology*; D001426:Bacterial Proteins / Q000378:metabolism; D012481:Salmonella Infections, Animal / Q000378:metabolism / Q000503:physiopathology; D012486:Salmonella typhimurium / Q000254:growth & development / Q000472:pathogenicity; D015398:Signal Transduction
chemical_list: D001426:Bacterial Proteins