[Toxic effects of anesthetics: rhabdomyolysis with acute renal insufficiency].
Rhabdomyolysis is rare but serious complication of general anesthesia. The authors report a case of anesthesia-induced severe rhabdomyoloysis in previously healthy male. First symptoms and signs occurred after the surgery was finished, and consisted of muscular pain and cardiac arrhythmia. Laboratory analysis revealed metabolic acidosis, electrolyte disturbances and marked elevation of enzyme activity, with extremely high value of creatine phosphokinase (CPK)-173920 U/I on the second day. Acute renal failure has also developed. Based on the reports of similar cases, the etiology, pathogenesis, therapy and prevention of rhabdomyolysis were discussed.
Jović-Stosić
J
J
Randjelović
S
S
Raicević
B
B
D058186:Acute Kidney Injury / Q000175:diagnosis*; D000328:Adult; D000768:Anesthesia, General / Q000009:adverse effects*; D000777:Anesthetics / Q000008:administration & dosage*; D005283:Fentanyl / Q000009:adverse effects; D006801:Humans; D008297:Male; D012206:Rhabdomyolysis / Q000139:chemically induced*; D013874:Thiopental / Q000009:adverse effects
D000777:Anesthetics; D013874:Thiopental; D005283:Fentanyl