title: Deployment of disease resistance genes by plant transformation - a 'mix and match' approach.
abstract: Breeding for disease resistance has often resulted in the evolution of a matching virulence within the pathogen population, leading to an apparent 'breakdown' of resistance. In general, plant breeders have responded by introducing new genes for resistance, with similar consequences. This has led to 'boom-bust' cycles, where varieties possessing effective resistance are grown on an expanding acreage (boom) until matching virulence evolves and spreads within the pathogen population (bust). A variety of resistance genes have recently been identified and characterized in model systems. Together with the development of efficient plant transformation systems these genes offer an alternative means to introduce specific resistance into a crop improvement programme. However, unless the resistance genes are deployed with care, the boom-bust cycle is likely to be perpetuated.
authors.affiliation: Horticulture Research International, Wellesbourne, Warwick, UK CV35 9EF.
authors.initials: D
authors.lastname: Pink
authors.initials: I
authors.lastname: Puddephat