title: [Intraoperative radiotherapy in the combined treatment of pancreatic cancers].
abstract: Pancreatic cancer is a highly lethal disease either for the high incidence of distant metastases or for the frequent local recidive also after potentially curative resection. For this reason new multimodality approaches have to be investigated. Intraoperative radiotherapy (IORT) permits to administer a high dose to the tumor or to the retropancreatic tissues and to the regional lymph nodes. Literature data suggest it is possible a better local control and perhaps a better survival than the surgery alone or the palliative treatments by the use of schedules with IORT. Anyway they are retrospective data and IORT is an investigational method which has to be indagate in the combined modality approaches to this disease.
authors.affiliation: Divisioni di Radioterapia, Ospedale Santa Chiara, Trento, Italia.
authors.forename: G
authors.initials: G
authors.lastname: Fellin
authors.forename: G
authors.initials: G
authors.lastname: Pani
authors.forename: L
authors.initials: L
authors.lastname: Tomio
authors.forename: G
authors.initials: G
authors.lastname: Tirone
authors.forename: C
authors.initials: C
authors.lastname: Eccher
mesh_terms: D006801:Humans; D007432:Intraoperative Period; D010190:Pancreatic Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D018714:Radiotherapy, Adjuvant / Q000379:methods; D016019:Survival Analysis; D016896:Treatment Outcome