Necrobiosis lipoidica: only a minority of patients have diabetes mellitus.
Although it is commonly accepted that necrobiosis lipoidica (NL) is associated with diabetes mellitus (DM), there is some controversy regarding the degree of this association. In a retrospective review of 65 patients with NL attending our dermatology out-patient clinics we found that just seven (11%) were known to have DM at the time of presentation. Seven further patients (11%) were diagnosed as having impaired glucose tolerance/DM at presentation and over a 15-year follow-up period. Thus, only a minority of our patients with NL had DM.
O'Toole
E A
EA
Department of Dermatology, St James's Hospital and Trinity College Dublin, Ireland.
Kennedy
U
U
Nolan
J J
JJ
Young
M M
MM
Rogers
S
S
Barnes
L
L
D000287:Administration, Topical; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000235:genetics; D016640:Diabetes, Gestational / Q000150:complications; D005192:Family Health; D005260:Female; D005500:Follow-Up Studies; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D009335:Necrobiosis Lipoidica / Q000150:complications* / Q000235:genetics / Q000473:pathology; D011247:Pregnancy; D012189:Retrospective Studies; D018570:Risk Assessment; D013997:Time Factors
D000305:Adrenal Cortex Hormones