Clinical significance of plasma HDL subfractions (HDL2, HDL3) in patients with peripheral arterial disease (PAD) in the Greek population.
OBJECTIVE
In this study the major high density lipoprotein (HDL) subfractions (HDL2, HDL3) were examined, in angiographically selected patients with peripheral arterial disease (PAD).


RESULTS
Patients with PAD have significantly high triglyceride levels. HDL2 and HDL3 levels were found significantly reduced in patients with PAD. Also, the ratio HDL2-C/HDL3-C was significantly reduced in patients with PAD.


CONCLUSIONS
The aim of the present study is to provide additional support to the hypothesis that the determination of HDL subfractions could be useful to elucidate possible mechanism(s) for a better assessment of the risk profile for PAD.
Kalofoutis
A
A
Department of Biological Chemistry, University of Athens, School of Medicine, Greece.
Papapanagiotou
A
A
Tzivras
M
M
D000368:Aged; D000792:Angiography; D001158:Arteries / Q000000981:diagnostic imaging*; D008076:Cholesterol, HDL / Q000097:blood; D003327:Coronary Disease / Q000097:blood / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006115:Greece; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000150:complications / Q000175:diagnosis; D006973:Hypertension / Q000097:blood / Q000175:diagnosis / Q000209:etiology; D008075:Lipoproteins, HDL / Q000097:blood*; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000097:blood* / Q000175:diagnosis / Q000209:etiology; D012016:Reference Values; D018570:Risk Assessment; D014463:Ultrasonography
D008076:Cholesterol, HDL; D008075:Lipoproteins, HDL