title: [Adrenal incidentaloma: a dopamine-secreting pheochromocytoma with an atypical clinical picture. A case report and review of the literature].
abstract: BACKGROUND
  The increasing and consolidated uses of US and CT scan in the diagnosis of abdominal diseases has improved the detection of adrenal asymptomatic masses. Current literature points out that these nodules are identified by 1:100 abdominal CT every year. On the other hand, about 50% of the adrenal tumors are discovered by autopsy. The diagnostic difficulties may be due both to clinical silence and to atypical clinical expressions of the neoplasm--as in the case report--where a pheochromocytoma shows non-specific abdominal symptoms rather than the typical signs of catecholamine overproduction.
  
  
  METHODS
  Author,s report a suprarenal right pheochromocytoma, secreting dopamine prevalently. The tumor showed abdominal symptoms without history of hypertensive paroxysms, or better still in normotension regimen.
  
  
  CONCLUSIONS
  According to current literature, abdominal symptoms occur in about 7% of all suprarenal pheochromocytomas. Most of these tumors prevalently secrete dopamine, that seems to make the prognosis worse. US, CT scan and CT-guided fine needle biopsy weren't able to characterize the real nature of the adrenal incidentaloma. On the contrary, the hormonal screening--by monitoring the urinary VMA and fractioned catecholamines through 24 hours--was decisive for the diagnosis of pheochromocytoma. The adrenal incidentalomas diagnostic significance is tied to the concept that adrenalectomy can change their prognosis, especially in case of pheochromocytoma, where a recovery rate about 90% can be achieved. Authors agree that adrenalectomy my must be performed in all case of "functioning" adrenal tumors and "nonfunctioning" ones with > 6 cm size. Of last years the laparoscopic approach has extended the adrenalectomy's indications to mass with size ranging between 3 and 6 cm., while lesions < 3 cm. size require only a follow up by means of imaging techniques and hormonal monitoring.
authors.affiliation: Cattedra di Chirurgia Generale, Università degli Studi G. D'Annunzio, Chieti.
authors.forename: M
authors.initials: M
authors.lastname: Bartolacci
authors.forename: S
authors.initials: S
authors.lastname: Bartolacci
authors.forename: E
authors.initials: E
authors.lastname: Leombruni
authors.forename: A
authors.initials: A
authors.lastname: Annunziata
authors.forename: M
authors.initials: M
authors.lastname: Di Rienzo
authors.forename: N
authors.initials: N
authors.lastname: Picardi
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D000311:Adrenal Glands / Q000000981:diagnostic imaging / Q000473:pathology; D000315:Adrenalectomy; D000368:Aged; D001707:Biopsy, Needle; D004298:Dopamine / Q000378:metabolism*; D005260:Female; D006801:Humans; D010673:Pheochromocytoma / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D004298:Dopamine