title: Outcome and risk factors in octogenarians undergoing open-heart surgery.
abstract: OBJECTIVE
  Increasing numbers of elderly (aged > 80 years) patients are being referred for cardiac surgery, and results for coronary artery bypass grafting (CABG) are generally better than for combined CABG and valve replacement.
  
  
  METHODS
  During the past 55 months, 77 octogenarians underwent cardiac intervention in our institution. Forty-five patients (mean age 82.5 years) underwent CABG alone; surgery was elective in 33% of patients and 2.7 +/- 1.0 grafts per patient were performed. Thirty-two patients (mean age 82.4 years) underwent combined CABG and valve surgery (28 aortic, four mitral); 2.1 +/- 0.8 grafts per patient were performed and 65% of cases were emergencies.
  
  
  RESULTS
  In patients undergoing CABG alone, the operative mortality rate was 2% and rose to 4% (n = 2) at the end of follow up. Mean NYHA functional class improved significantly from 3.5 +/- 0.5 to 1.4 +/- 0.3 after surgery (p < 0.05) and most patients reported marked improvement in their quality of life. In CABG + valve surgery patients, the operative mortality rate was 6% (n = 2) and reached 18% by the end of follow up. In these patients the complication rate was 24% and mean hospitalization stay 11.0 +/- 2.9 days, while mean NYHA functional class improved from 3.4 +/- 0.6 to 1.2 +/- 0.5. Data analysis revealed that mitral regurgitation combined with coronary artery disease (p < 0.03) and prolonged cross-clamping time (p < 0.01) were the most important independent factors for mortality.
  
  
  CONCLUSIONS
  This study confirms that, in selected elderly patients, combined CABG and cardiac surgery can achieve good postoperative results.
authors.affiliation: Department of Cardiothoracic Surgery, Rabin Medical Center, Petach Tikva, Israel.
authors.forename: G
authors.initials: G
authors.lastname: Sahar
authors.forename: D
authors.initials: D
authors.lastname: Abramov
authors.forename: E
authors.initials: E
authors.lastname: Erez
authors.forename: A
authors.initials: A
authors.lastname: Sagie
authors.forename: J
authors.initials: J
authors.lastname: Barak
authors.forename: E
authors.initials: E
authors.lastname: Raanani
authors.forename: J
authors.initials: J
authors.lastname: Sulkes
authors.forename: B A
authors.initials: BA
authors.lastname: Vidne
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001026:Coronary Artery Bypass / Q000401:mortality*; D003327:Coronary Disease / Q000601:surgery; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000601:surgery; D019918:Heart Valve Prosthesis Implantation / Q000401:mortality*; D006801:Humans; D011183:Postoperative Complications / Q000401:mortality; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome