Use of ADCON in neurosurgery: preclinical review.
ADCON-L and ADCON-T/N are two bioabsorbable adhesion barrier gels designed to inhibit post-operative fibrosis around the dura and nerve structure. Two ADCON products were evaluated in animal models emulating their use in neurosurgery. In all studies ADCON-L and ADCON-T/N were safe and effective barriers to post-operative peridural and perineural fibrosis.
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Gliatech Inc., Cleveland, Ohio 44122, USA.
Frederickson
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D000818:Animals; D004195:Disease Models, Animal; D017586:Diskectomy / Q000009:adverse effects; D004353:Drug Evaluation, Preclinical; D005355:Fibrosis / Q000517:prevention & control; D005782:Gels / Q000627:therapeutic use*; D007796:Laminectomy / Q000009:adverse effects; D009493:Neurosurgery; D009930:Organic Chemicals; D011183:Postoperative Complications / Q000517:prevention & control*
C104199:ADCON-L; D005782:Gels; D009930:Organic Chemicals