Equilin.
3-Hydroxyestra-1,3,5(10),7-tetraen-17-one, C18H20O2, crystallizes in space group P2(1)2(1)2(1) from ethyl acetate. The planarity of the B ring, and the difference in puckering of the C and D rings from that of estrone, are due to the presence of the C7 = C8 double bond, which may explain its function as an inhibitor of human type 1 17 beta-hydroxysteroid dehydrogenase, instead of being its substrate.
Sawicki
M W
MW
Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
Li
N
N
Ghosh
D
D
D018360:Crystallography, X-Ray; D004857:Equilin / Q000737:chemistry*; D015914:Estrogen Replacement Therapy; D006801:Humans; D008958:Models, Molecular
D004857:Equilin