Luisols A and B, new aromatic tetraols produced by an estuarine marine bacterium of the genus Streptomyces (Actinomycetales).
Luisols A (1) and B (2), two new aromatic tetraols, have been isolated from the cultivation broth of an estuarine marine actinomycete of the genus Streptomyces (strain #CNH-370). The structures of luisols A and B were assigned by combined spectroscopic methods, including extensive 2D NMR experiments. Luisol A appears related to the anthraquinone antibiotics of the granaticin class, while the structure of luisol B contains the rare epoxynaphtho[2,3c]furan, a structural feature found in only one natural product, the fungal metabolite anthrinone.
Cheng
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Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California-San Diego, La Jolla, California 92093-0236, USA.
Jensen
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PR
Fenical
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D000880:Anthraquinones; D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D005663:Furans; D009682:Magnetic Resonance Spectroscopy; D009284:Naphthols; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013302:Streptomyces / Q000737:chemistry*
D000880:Anthraquinones; D000900:Anti-Bacterial Agents; D005663:Furans; D009284:Naphthols; C119454:luisol A; C119455:luisol B