title: Tissue response to an epoxy resin-based root canal sealer.
abstract: The objective of the present study was to evaluate two different types of root canal sealers: AH Plus (an epoxy resin-based sealer) and Fill Canal (a zinc oxide-eugenol based sealer). A total of 34 root canals with vital pulp from dogs' premolars were used. After instrumentation, the root canals were filled with gutta-percha and AH Plus or gutta-percha and Fill Canal sealers using a classical technique of lateral condensation. After histological processing, the sections were stained with hematoxylineosin or Mallory's trichrome stain. Inflammatory cells or areas of necrosis were not associated with AH Plus. Hard tissue formation apically to the material was observed in 14 specimens. The Fill Canal sealer presented an inflammatory response of moderate intensity in the periapical region, mainly adjacent to the material.
authors.affiliation: Department of Endodontics, School of Dentistry, Araraquara, Paulista State University, Brazil.
authors.forename: M R
authors.initials: MR
authors.lastname: Leonardo
authors.forename: L A
authors.initials: LA
authors.lastname: da Silva
authors.forename: W A
authors.initials: WA
authors.lastname: Almeida
authors.forename: L S
authors.initials: LS
authors.lastname: Utrilla
mesh_terms: D000818:Animals; D001466:Barium Sulfate / Q000494:pharmacology; D001672:Biocompatible Materials / Q000494:pharmacology; D001729:Bismuth / Q000494:pharmacology; D001881:Borates / Q000494:pharmacology; D004285:Dogs; D004338:Drug Combinations; D004853:Epoxy Resins / Q000494:pharmacology*; D005054:Eugenol / Q000494:pharmacology; D005069:Evaluation Studies as Topic; D010485:Periapical Periodontitis / Q000139:chemically induced; D010486:Periapical Tissue / Q000187:drug effects*; D012117:Resins, Synthetic / Q000494:pharmacology; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D015034:Zinc Oxide / Q000494:pharmacology
chemical_list: D001672:Biocompatible Materials; D001881:Borates; D004338:Drug Combinations; D004853:Epoxy Resins; D012117:Resins, Synthetic; D012387:Root Canal Filling Materials; C534916:epoxy resin-based root canal sealer; D001466:Barium Sulfate; D005054:Eugenol; C038425:Fillcanal; D015034:Zinc Oxide; D001729:Bismuth