Effects of Azadirachta indica leaves on the seminal vesicles and ventral prostate in albino rats.
Oral administration of 20, 40, 60, mg of dry Azadirachta indica leaf powder for 24 days resulted in decrease in the weights of seminal vesicles and ventral prostate, reduction in epithelial height, nuclear diameter and the secretory material in the lumen. Biochemically, there was a decrease in total protein, acid phosphatase activities. Seminal vesicles and ventral prostate being androgen dependent, the regressive changes histologically as well as biochemically, suggests the antiandrogenic property of the neem leaves.
Kasutri
M
M
Department of Zoology, Karnatak University, Dharwad.
Ahmed
R N
RN
Pathan
K M
KM
Shaikh
P D
PD
Manivannan
B
B
D000135:Acid Phosphatase / Q000378:metabolism; D000284:Administration, Oral; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D005947:Glucose / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D018515:Plant Leaves / Q000737:chemistry*; D010946:Plants, Medicinal; D011208:Powders / Q000494:pharmacology; D011467:Prostate / Q000166:cytology / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D051381:Rats; D012669:Seminal Vesicles / Q000166:cytology / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism
D011208:Powders; D007770:L-Lactate Dehydrogenase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D005947:Glucose