title: [Embolia cutis medicamentosa (Nicolau syndrome) after intra-articular injection].
abstract: Embolia cutis medicamentosa (Nicolau Syndrome) is a very rare complication of intramuscular injections which presents with extensive necrosis of the injected skin area. Intra-arteria and/or para-arterial injections after prior perforation of certain vessels are discussed as possible pathogenetic mechanisms. We describe the occurrence of embolia cutis medicamentosa after intra-articular injections into the knee.
authors.affiliation: Klinik und Poliklinik für Hautkrankheiten, Westfälische Wilhelms-Universität Münster.
authors.forename: S
authors.initials: S
authors.lastname: Beissert
authors.forename: D
authors.initials: D
authors.lastname: Presser
authors.forename: A
authors.initials: A
authors.lastname: Rütter
authors.forename: D
authors.initials: D
authors.lastname: Metze
authors.forename: T A
authors.initials: TA
authors.lastname: Luger
authors.forename: T
authors.initials: T
authors.lastname: Schwarz
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects; D004617:Embolism / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007270:Injections, Intra-Articular / Q000009:adverse effects*; D007719:Knee Joint / Q000098:blood supply* / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D000077423:Polidocanol; D011092:Polyethylene Glycols / Q000008:administration & dosage / Q000009:adverse effects; D011239:Prednisolone / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D012597:Sclerosing Solutions / Q000008:administration & dosage / Q000009:adverse effects; D012867:Skin / Q000098:blood supply* / Q000473:pathology; D013577:Syndrome
chemical_list: D000893:Anti-Inflammatory Agents; D012597:Sclerosing Solutions; D000077423:Polidocanol; D011092:Polyethylene Glycols; C009935:prednisolone acetate; D011239:Prednisolone