Postchemotherapy retroperitoneal residual mass in infantile yolk sac tumor.
BACKGROUND
Persistent postchemotherapy retroperitoneal residual mass with normalization of alpha-fetoprotein (AFP) in infantile yolk sac tumor is rare.


RESULTS
A 38-month-old boy with recurrent yolk sac tumor was treated with cisplatin-based combination chemotherapy. After chemotherapy, the retroperitoneal lymph node metastasis, 7 x 6 cm in size, decreased to 2 x 2 cm. Serum AFP levels returned to normal. The retroperitoneal residual mass was resected and histologically showed complete necrosis without viable cancer cells.


CONCLUSIONS
The patient has remained free of disease for 36 months after operation.
Kuo
J Y
JY
Division of Urology, Veterans General Hospital-Taipei, Taiwan, Republic of China. juku.@vghtpe.gov.tw
Hsieh
Y L
YL
Chin
T
T
Wei
C
C
Chen
K K
KK
Chang
L S
LS
D000970:Antineoplastic Agents / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D018240:Endodermal Sinus Tumor / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000556:secondary; D006801:Humans; D006869:Hydronephrosis / Q000000981:diagnostic imaging; D007223:Infant; D008207:Lymphatic Metastasis; D008297:Male; D018365:Neoplasm, Residual; D011859:Radiography; D012186:Retroperitoneal Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000556:secondary; D000509:alpha-Fetoproteins / Q000032:analysis
D000970:Antineoplastic Agents; D000509:alpha-Fetoproteins; D002945:Cisplatin