title: [Neuro-meningeal location of Richter syndrome].
abstract: BACKGROUND
  The authors report a case of neurologic manifestations revealing Richter's syndrome in chronic lymphocytic leukemia.
  
  
  METHODS
  Cranial nerve palsies were the initial manifestation of the disease. Computed tomography and magnetic resonance imaging were normal. Cerebrospinal fluid analysis with alkaline phosphatase-antialkaline phosphatase revealed the existence of a large-cell lymphoma.
  
  
  CONCLUSIONS
  Clinical aspects of this unusual localization of Richter's syndrome are reviewed.
authors.affiliation: Service de médecine interne A, CHU Hôtel-Dieu, place Alexis-Ricordeau, Nantes, France.
authors.forename: G
authors.initials: G
authors.lastname: Agard
authors.forename: M
authors.initials: M
authors.lastname: Hamidou
authors.forename: S
authors.initials: S
authors.lastname: Leautez
authors.forename: R
authors.initials: R
authors.lastname: Garand
authors.forename: J Y
authors.initials: JY
authors.lastname: Grolleau
mesh_terms: D000010:Abducens Nerve / Q000473:pathology; D000469:Alkaline Phosphatase / Q000134:cerebrospinal fluid; D003390:Cranial Nerve Neoplasms / Q000134:cerebrospinal fluid / Q000473:pathology*; D005260:Female; D006429:Hemiplegia / Q000473:pathology; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000134:cerebrospinal fluid / Q000473:pathology*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010243:Paralysis / Q000473:pathology; D013120:Spinal Cord Neoplasms / Q000134:cerebrospinal fluid / Q000473:pathology*; D013577:Syndrome
chemical_list: D000469:Alkaline Phosphatase