title: Severe cerebral venous sinus thrombosis and dural arteriovenous fistula in an infant with protein S deficiency.
abstract: A 12-month-old infant presented with cerebral seizures and neurological deficits. MRI scan of the brain and angiography showed massive cerebral venous sinus thrombosis complicated by a dural arteriovenous fistula. Subsequent clotting analysis revealed a protein S deficiency. Screening for inherited coagulation inhibitor deficiency is recommended in children with unexplained or atypical thrombotic events.
authors.affiliation: Kinderklinik Minden, Germany.
authors.forename: O
authors.initials: O
authors.lastname: Witt
authors.forename: P L
authors.initials: PL
authors.lastname: Pereira
authors.forename: W
authors.initials: W
authors.lastname: Tillmann
mesh_terms: D001164:Arteriovenous Fistula / Q000150:complications* / Q000473:pathology; D002533:Cerebral Angiography; D002675:Child, Preschool; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D002538:Intracranial Arteriovenous Malformations / Q000150:complications* / Q000235:genetics / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D018455:Protein S Deficiency / Q000150:complications* / Q000235:genetics; D012640:Seizures / Q000209:etiology; D012851:Sinus Thrombosis, Intracranial / Q000150:complications* / Q000175:diagnosis*