title: Botulinum toxin: potent poison, potent medicine.
abstract: Botulinum toxin is now used to treat a wide variety of cholinergic disorders, ranging from mild tics to more disabling forms of dystonia. The demonstrated safety of such treatments has encouraged further exploitation of the toxin's unique properties. With genetic manipulation of structural features, this poisonous substance could turn out to be an efficient carrier of oral medications and vaccines.
authors.affiliation: Division of Occupational and Environmental Health Sciences, Jefferson Medical College, Philadelphia, USA.
authors.forename: L L
authors.initials: LL
authors.lastname: Simpson
mesh_terms: D018726:Anti-Dyskinesia Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001428:Bacterial Vaccines; D001905:Botulinum Toxins / Q000276:immunology / Q000494:pharmacology / Q000627:therapeutic use*; D001906:Botulism / Q000517:prevention & control; D004421:Dystonia / Q000188:drug therapy*; D006801:Humans; D011042:Poisons / Q000378:metabolism; D014481:United States
chemical_list: D018726:Anti-Dyskinesia Agents; D001428:Bacterial Vaccines; D011042:Poisons; D001905:Botulinum Toxins