title: Necrobiosis lipoidica: only a minority of patients have diabetes mellitus.
abstract: Although it is commonly accepted that necrobiosis lipoidica (NL) is associated with diabetes mellitus (DM), there is some controversy regarding the degree of this association. In a retrospective review of 65 patients with NL attending our dermatology out-patient clinics we found that just seven (11%) were known to have DM at the time of presentation. Seven further patients (11%) were diagnosed as having impaired glucose tolerance/DM at presentation and over a 15-year follow-up period. Thus, only a minority of our patients with NL had DM.
authors.affiliation: Department of Dermatology, St James's Hospital and Trinity College Dublin, Ireland.
authors.forename: E A
authors.initials: EA
authors.lastname: O'Toole
authors.forename: U
authors.initials: U
authors.lastname: Kennedy
authors.forename: J J
authors.initials: JJ
authors.lastname: Nolan
authors.forename: M M
authors.initials: MM
authors.lastname: Young
authors.forename: S
authors.initials: S
authors.lastname: Rogers
authors.forename: L
authors.initials: L
authors.lastname: Barnes
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000235:genetics; D016640:Diabetes, Gestational / Q000150:complications; D005192:Family Health; D005260:Female; D005500:Follow-Up Studies; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D009335:Necrobiosis Lipoidica / Q000150:complications* / Q000235:genetics / Q000473:pathology; D011247:Pregnancy; D012189:Retrospective Studies; D018570:Risk Assessment; D013997:Time Factors
chemical_list: D000305:Adrenal Cortex Hormones