title: [Autoimmune hemolytic anemia associated with a mature ovarian teratoma].
abstract: The association of autoimmune hemolytic anemia and mature teratoma of the ovary is rare, particularly in childhood, but must be known and looked for since the treatment of teratoma allows to cure anemia as well.
  
  
  METHODS
  A 9 year-old girl was admitted for hemolytic anemia. The etiologic work-up revealed an autoimmune mechanism (IgG autoantibodies with complement), as well as an ovarian tumor after ultrasound sonography of the abdomen and pelvis. Surgical excision of the tumor was complete and uncomplicated. Pathological examination concluded to a mature teratoma. Anemia, as well as the signs of autoimmunity, disappeared a few weeks later and the child is doing well with several months of follow-up.
  
  
  CONCLUSIONS
  This second reported pediatric case shows that an ovarian teratoma should be searched for with ultrasound sonography in any girl presenting with autoimmune hemolytic anemia, since surgical excision is sufficient to cure both anemia and the tumor.
authors.affiliation: Unité d'hémato-oncologie pédiatrique, CHU Purpan, Toulouse, France.
authors.forename: I
authors.initials: I
authors.lastname: Glorieux
authors.forename: V
authors.initials: V
authors.lastname: Chabbert
authors.forename: H
authors.initials: H
authors.lastname: Rubie
authors.forename: C
authors.initials: C
authors.lastname: Baunin
authors.forename: M H
authors.initials: MH
authors.lastname: Gaspard
authors.forename: J
authors.initials: J
authors.lastname: Guitard
authors.forename: I
authors.initials: I
authors.lastname: Duga
authors.forename: A
authors.initials: A
authors.lastname: Suc
authors.forename: C
authors.initials: C
authors.lastname: Puget
authors.forename: A
authors.initials: A
authors.lastname: Robert
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood / Q000150:complications*; D001323:Autoantibodies / Q000097:blood; D002648:Child; D003165:Complement System Proteins / Q000032:analysis; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D010051:Ovarian Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D013724:Teratoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D014463:Ultrasonography
chemical_list: D001323:Autoantibodies; D007074:Immunoglobulin G; D003165:Complement System Proteins