title: Drug interactions and anti-infective therapies.
abstract: Drug interactions are an important and often underappreciated cause of adverse clinical outcomes. This review considers the mechanisms for several clinically important drug interactions that involve the major classes of anti-infective agents. This approach is intended to complement the use of text-based references and computer databases so that physicians and pharmacists can avoid prescribing and dispensing drugs that have adverse interactions.
authors.affiliation: Dallas Veterans Affairs Medical Center, and the Department of Medicine, University of Texas Southwestern Medical Center, 75216, USA.
authors.forename: C R
authors.initials: CR
authors.lastname: Gregg
mesh_terms: D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology; D000998:Antiviral Agents / Q000494:pharmacology; D001682:Biological Availability; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System / Q000187:drug effects; D004347:Drug Interactions; D004791:Enzyme Inhibitors; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D000998:Antiviral Agents; D065607:Cytochrome P-450 Enzyme Inhibitors; D004791:Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System