title: Scleromalacia following trabeculectomy with intraoperative mitomycin C.
abstract: OBJECTIVE
  To report the development of scleromalacia in pediatric age as a complication of trabeculectomy with the adjunctive use of intra-operative mitomycin C.
  
  
  METHODS
  Reported are 2 patients who developed scleromalacia following trabeculectomy combined with intra-operative 0.4 mg/ml mitomycin C application for 5 minutes for refractory glaucoma in aphakic bullous keratopathy and penetrating keratoplasty.
  
  
  RESULTS
  Scleromalacia localised in the surgical area developed in 2 young patients. Scleromalacia remained stable in both patients after 6 and 24 months follow-ups.
  
  
  CONCLUSIONS
  It is suggested that this procedure be done more selectively, especially in young patients, with a shorter application time and using a lower concentration.
authors.affiliation: Department of Ophthalmology, Başkent University Hospitals, Ankara, Turkey.
authors.forename: Y A
authors.initials: YA
authors.lastname: Akova
authors.forename: F
authors.initials: F
authors.lastname: Koç
authors.forename: I
authors.initials: I
authors.lastname: Yalvaç
authors.forename: S
authors.initials: S
authors.lastname: Duman
mesh_terms: D017024:Chemotherapy, Adjuvant; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000601:surgery; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D008297:Male; D016685:Mitomycin / Q000009:adverse effects*; D015422:Scleral Diseases / Q000209:etiology* / Q000473:pathology; D014130:Trabeculectomy / Q000009:adverse effects*
chemical_list: D016685:Mitomycin