title: Akinetic mutism and mixed transcortical aphasia following left thalamo-mesencephalic infarction.
abstract: A 54-year-old man developed somnolent akinetic mutism and acute mixed transcortical aphasia following a left thalamo-mesencephalic infarction. He also exhibited behavioural changes, namely apathy, slowness, lack of spontaneity, disinhibition, perseveration, gait apraxia and incontinence consistent with frontal lobe dysfunction. Presumably the akinetic mutism and language dysfunction were due to the thalamic stroke. All the manifestations could be related to interruption of the frontal-subcortical circuitry.
authors.affiliation: Blacktown-Mount Druitt Health, Blacktown, NSW, Australia.
authors.forename: N
authors.initials: N
authors.lastname: Nagaratnam
authors.forename: C
authors.initials: C
authors.lastname: McNeil
authors.forename: J S
authors.initials: JS
authors.lastname: Gilhotra
mesh_terms: D000339:Affect; D001037:Aphasia / Q000000981:diagnostic imaging / Q000209:etiology*; D002544:Cerebral Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000523:psychology; D005625:Frontal Lobe / Q000503:physiopathology; D005684:Gait; D006801:Humans; D008297:Male; D008636:Mesencephalon / Q000000981:diagnostic imaging*; D008875:Middle Aged; D009155:Mutism / Q000000981:diagnostic imaging / Q000209:etiology*; D011859:Radiography; D013788:Thalamus / Q000000981:diagnostic imaging*