title: [Use of gabapentin in glossopharyngeal neuralgia].
abstract: Anticonvulsant drugs, especially carbamazepine, are the treatment of choice for glossopharyngeal neuralgia. If no clinical response is obtained, surgical treatment, including nerve section or decompression, may be required. We report the results obtained with a new anticonvulsant, gabapentin, as an alternative for cases of carbamazepine failure. In 7 patients with bouts of glosso-pharyngeal neuralgia refractory to the usual medical treatment, gabapentin produced improvement in 5 patients. Response was poor in patients who had undergone surgical nerve decompression. Gabapentin was concluded to be an effective therapeutic option for neuralgia of the IXth cranial nerve before surgery.
authors.affiliation: Servicio de ORL, Hospital Clínico Universitario, Valencia, Valencia, España.
authors.forename: F J
authors.initials: FJ
authors.lastname: García Callejo
authors.forename: J
authors.initials: J
authors.lastname: Marco Algarra
authors.forename: F
authors.initials: F
authors.lastname: Talamantes Escribá
authors.forename: M P
authors.initials: MP
authors.lastname: Martínez Beneyto
authors.forename: M
authors.initials: M
authors.lastname: Esparcia Navarro
authors.forename: A
authors.initials: A
authors.lastname: Morant Ventura
mesh_terms: D000085:Acetates / Q000627:therapeutic use*; D000328:Adult; D000588:Amines; D000700:Analgesics / Q000627:therapeutic use*; D003509:Cyclohexanecarboxylic Acids; D005260:Female; D000077206:Gabapentin; D005930:Glossopharyngeal Nerve / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome; D005680:gamma-Aminobutyric Acid
chemical_list: D000085:Acetates; D000588:Amines; D000700:Analgesics; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin