title: Tissue necrosis after subgingival irrigation with fluoride solution.
abstract: Irrigation of periodontal pockets with fluoride solution after scaling and root planing is occasionally recommended to inhibit the growth of pathogenic bacteria in the periodontal pocket. At the same time, irrigation enables mechanical removal of loosely adhering plaque and debris. Due to its toxicity, fluoride solution deposited in the periodontium may lead to tissue damage. We report in this paper, a case of extensive periodontal tissue necrosis and permanent loss of alveolar bone after irrigation of periodontal pockets with stannous fluoride solution. The literature on the toxic effects of fluoride on the local tissues is briefly reviewed and arguments for a re-evaluation of the use of stannous fluoride for pocket irrigation are provided.
authors.affiliation: Department of Oral Biology, School of Dentistry, Umeå University, Sweden. staffan.sjostrom@oralbio.umu.se
authors.forename: S
authors.initials: S
authors.lastname: Sjöström
authors.forename: S
authors.initials: S
authors.lastname: Kalfas
mesh_terms: D000368:Aged; D016301:Alveolar Bone Loss / Q000139:chemically induced; D000891:Anti-Infective Agents, Local / Q000009:adverse effects*; D001419:Bacteria / Q000187:drug effects; D003741:Dental Deposits / Q000628:therapy; D003773:Dental Plaque / Q000628:therapy; D012534:Dental Scaling; D005889:Gingival Recession / Q000139:chemically induced; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000187:drug effects* / Q000473:pathology; D009336:Necrosis; D010514:Periodontal Pocket / Q000382:microbiology*; D016745:Root Planing; D013280:Stomatitis / Q000139:chemically induced; D007507:Therapeutic Irrigation / Q000009:adverse effects; D014002:Tin Fluorides / Q000009:adverse effects*
chemical_list: D000891:Anti-Infective Agents, Local; D014002:Tin Fluorides