title: Myasthenia gravis activities of daily living profile.
abstract: The authors have developed an MG activities of daily living (ADL) profile (MG-ADL)-a simple eight-question survey of MG symptoms. In 254 consecutive encounters with established MG patients, the authors compared scores from the MG-ADL to the quantitative MG score (QMG)-a standardized, reliable scale used in clinical trials. The mean MG-ADL score was 4.89+/-3.63. The mean QMG score was 10.80+/-5.70. Pearson's correlation coefficient was 0.583 (p < 0.001). The MG-ADL is an easy-to-administer survey of MG that correlates well with the QMG and can serve as a secondary efficacy measurement in clinical trials.
authors.affiliation: Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75235-8897, USA.
authors.forename: G I
authors.initials: GI
authors.lastname: Wolfe
authors.forename: L
authors.initials: L
authors.lastname: Herbelin
authors.forename: S P
authors.initials: SP
authors.lastname: Nations
authors.forename: B
authors.initials: B
authors.lastname: Foster
authors.forename: W W
authors.initials: WW
authors.lastname: Bryan
authors.forename: R J
authors.initials: RJ
authors.lastname: Barohn
mesh_terms: D000203:Activities of Daily Living; D003625:Data Collection; D005260:Female; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000503:physiopathology*