title: The safety of pharmaceutical excipients.
abstract: Excipients are essential ingredients of medicinal products. Approximately 1000 excipients are today in use in marketed pharmaceuticals. The safety issues regarding excipients can be classified into three categories: quality, toxicology and improper use. An overview of the current status, regulatory requirements and improvements is given.
authors.affiliation: Servier International Research Institute, Courbevoie, France.
authors.forename: H J
authors.initials: HJ
authors.lastname: de Jong
mesh_terms: D005060:Europe; D005079:Excipients / Q000009:adverse effects / Q000592:standards*; D005602:France; D006801:Humans; D007880:Legislation, Drug; D011785:Quality Assurance, Health Care; D012449:Safety
chemical_list: D005079:Excipients