[use of a Staphylococcus bacterial vaccine in pediatric patients with chronic sinusitis].
BACKGROUND
The antigenic extracts of bacterial vaccine (Staphylococcus aureus) they increase the phagocitosis, the immunoglobulins concentrations and they help in the immunologic response.


OBJECTIVE
To determine the effectiveness of the bacterial vaccine in patient pediatric with chronic sinusitis.


METHODS
Through a prospective, observational, descriptive and logitudinal study 50 patients were studied with clinical and radiological diagnosis of chronic sinusitis in the period of May from 1997 to July of 1998; they talked to three outlines of antibiotics, they were made studies of cytology hematic, of snot, perspired pharyngeal and immunoglobulin determination and x-rays of breasts paranasals. The extract of 0.1 ml was applied twice up to 0.5 ml per week, subcutaneous trial during eight months, with pursuit of six months and control of cytology hematic, as well as immunoglobulin determination.


RESULTS
82% (41) of the patients they improved and nine (18%) they persisted with symptoms, of these five required the antimicrobials prescription, three tonsillectomi. There was an immunoglobulin increment, mainly of the IgA and IgG in 38 (76%) patient.
Martínez Pérez
A
A
Unidad de pediatría, Hospital General de México.
Chavarría Jiménez
M T
MT
Miranda Feria
A J
AJ
D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D011446:Prospective Studies; D012852:Sinusitis / Q000188:drug therapy*; D013209:Staphylococcal Vaccines / Q000627:therapeutic use*; D013211:Staphylococcus aureus
D013209:Staphylococcal Vaccines