title: [use of a Staphylococcus bacterial vaccine in pediatric patients with chronic sinusitis].
abstract: BACKGROUND
  The antigenic extracts of bacterial vaccine (Staphylococcus aureus) they increase the phagocitosis, the immunoglobulins concentrations and they help in the immunologic response.
  
  
  OBJECTIVE
  To determine the effectiveness of the bacterial vaccine in patient pediatric with chronic sinusitis.
  
  
  METHODS
  Through a prospective, observational, descriptive and logitudinal study 50 patients were studied with clinical and radiological diagnosis of chronic sinusitis in the period of May from 1997 to July of 1998; they talked to three outlines of antibiotics, they were made studies of cytology hematic, of snot, perspired pharyngeal and immunoglobulin determination and x-rays of breasts paranasals. The extract of 0.1 ml was applied twice up to 0.5 ml per week, subcutaneous trial during eight months, with pursuit of six months and control of cytology hematic, as well as immunoglobulin determination.
  
  
  RESULTS
  82% (41) of the patients they improved and nine (18%) they persisted with symptoms, of these five required the antimicrobials prescription, three tonsillectomi. There was an immunoglobulin increment, mainly of the IgA and IgG in 38 (76%) patient.
authors.affiliation: Unidad de pediatría, Hospital General de México.
authors.forename: A
authors.initials: A
authors.lastname: Martínez Pérez
authors.forename: M T
authors.initials: MT
authors.lastname: Chavarría Jiménez
authors.forename: A J
authors.initials: AJ
authors.lastname: Miranda Feria
mesh_terms: D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D011446:Prospective Studies; D012852:Sinusitis / Q000188:drug therapy*; D013209:Staphylococcal Vaccines / Q000627:therapeutic use*; D013211:Staphylococcus aureus
chemical_list: D013209:Staphylococcal Vaccines