Recent developments in oral multiphase and targeted release products.
This review examines recent approaches to formulation that are aimed at oral multiphase and targeted release products, and comments on their potential for commercial manufacture. In addition, it identifies a trend within current development in the formation of systems that are designed to alter specific absorption processes. This is in contrast to classical routes, which effectively adapt to normal physiological functions. These new approaches may have two major benefits in both facilitating consistent, reliable oral dosing of new complex molecules, such as those discovered within the biotechnology industry, and permitting dosage reduction of current common molecules.
Bowtle
WJ
MW ENCAP Ltd, 4 Dunlop Square, Livingston, UK EH54 8SB.