[Ultrasonic monitoring as a method of preventing risks of ovarian hyperstimulation during drug therapy].
OBJECTIVE
Ultrasonographic monitoring represents the most immediate method for an early confirmation of the onset of the worst complication of the pharmacological induction of ovulation: ovarian hyperstimulation. The aim of this study was to evaluate the incidence of this complication in a sample group of anovulatory patients receiving pharmacological treatment and undergoing repeated ultrasonographic monitoring.


METHODS
The authors analysed the controls performed during 1996-1997 in which a total of 413 cycles were stimulated. The patients included in the study group (mean age 28.5 years) were treated using clomiphene, oestradiol, FSH, LH and GnRH, and in 5 cases stimulation was preceded by suppression of the menstrual cycle using tryptorelin. Each patient was monitored with 3 scans, except for those treated with tryptorelin or GnRH who were more closely monitored.


RESULTS
In 413 patients included in this study the authors noted the onset of slight hyperstimulation in 6 cases (1.45%) which then resolved spontaneously without the need for hospitalisation.


CONCLUSIONS
The authors affirm that ultrasonographic monitoring represents a valid means of controlling and preventing the risks of ovarian hyperstimulation.
Grio
R
R
Dipartimento di Scienze Ginecologiche Ostetriche, Università degli Studi, Torino.
Patriarca
A
A
Ramondini
L
L
Ferrara
L
L
Curti
A
A
Piacentino
R
R
D000328:Adult; D005260:Female; D006801:Humans; D008186:Luteolytic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D008991:Monitoring, Physiologic; D016471:Ovarian Hyperstimulation Syndrome / Q000000981:diagnostic imaging* / Q000188:drug therapy; D010053:Ovary / Q000000981:diagnostic imaging; D010062:Ovulation Induction / Q000009:adverse effects* / Q000379:methods; D011247:Pregnancy; D012307:Risk Factors; D017329:Triptorelin Pamoate / Q000008:administration & dosage* / Q000009:adverse effects; D016216:Ultrasonography, Prenatal
D008186:Luteolytic Agents; D017329:Triptorelin Pamoate