Collagen-platelet interaction: platelet non-integrin receptors.
Platelet-collagen interaction is a complex event that involves ligand-receptor interaction. There are many adhesive non-integrin receptors for platelets to interact with various types of collagens. These non-integrin receptors also serve as signal transducers both from the outside of platelets to the inside and possibly vice versa. The present review covers basic aspects of non-integrin receptor function and various signal transduction pathways.
Chiang
T M
TM
Veterans Affairs Medical Center, University of Tennesse-Memphis, USA.
D000818:Animals; D001665:Binding Sites; D001792:Blood Platelets / Q000378:metabolism*; D003094:Collagen / Q000378:metabolism*; D006801:Humans; D016023:Integrins / Q000378:metabolism; D010716:Phosphatidylinositols / Q000378:metabolism; D010741:Phospholipases A / Q000378:metabolism; D010749:Phosphoprotein Phosphatases / Q000378:metabolism; D010766:Phosphorylation; D010974:Platelet Aggregation; D011956:Receptors, Cell Surface / Q000378:metabolism*; D038981:Receptors, Collagen; D015398:Signal Transduction
D016023:Integrins; D010716:Phosphatidylinositols; D011956:Receptors, Cell Surface; D038981:Receptors, Collagen; D003094:Collagen; D010741:Phospholipases A; D010749:Phosphoprotein Phosphatases