[Three children with systemic cat scratch disease].
Three girls with systemic cat scratch disease, aged 10, 13 and 9 years, were reported. They presented a prolonged fever and back pain in the early stage of the disease, and had no regional lymphadenopathy. Two of them had hepatosplenic granulomas, one with multiple 5 mm hypoechoic lesions in the liver and spleen, and the other with a single 2.5 cm hypodense lesion in the left hepatic lobe. The latter patient underwent a partial left hepatic lobectomy. All patients had elevated titers of antibodies to Bartonella henselae. Polymerase chain reaction detected B. henselae DNA in tissue specimens of the patient who underwent a hepatic lobectomy. Cat scratch disease should be recognized as a cause of fever of unknown origin because the prevalence of B henselae infection might be higher in Japan.
Murano
I
I
Department of Pediatrics, Yamaguchi Prefecture Central Hospital.
Yoshii
H
H
Kurashige
H
H
Sugio
Y
Y
Uchida
M
M
Shinohara
T
T
Tsuneoka
H
H
Yamamoto
K
K
Iino
H
H
Fujii
R
R
Fujisawa
K
K
Tsukahara
M
M
D000293:Adolescent; D002372:Cat-Scratch Disease / Q000175:diagnosis*; D002648:Child; D005260:Female; D005335:Fever of Unknown Origin; D006801:Humans