Simultaneous involvement of the jejunum and the colon by type-1 neurofibromatosis.
Type-1 neurofibromatosis (NF-1) or Von Recklinghausen disease is an autosomal dominant hereditary condition that may affect the gastrointestinal tract in 25% of cases and which takes three main forms: ganglioneuromatosis, stromal tumors, and tumors in the duodenum and periampullar region. Not infrequently, these patients present with gastrointestinal bleeding. We present the case of a 48-year-old patient diagnosed as having NF-1, with relapsing episodes of gastrointestinal hemorrhage, in which we discovered the simultaneous presence of a stromal tumor in the jejunum together with polypoid and diffuse ganglioneuromatosis in the colon.
Artaza
T
T
Dept. of Gastroenterology, Virgen de la Salud Hospital, Toledo, Spain.
García
J F
JF
González
C
C
Amengual
M
M
Mazarro
A
A
Rodríguez
R
R
Sánchez
J J
JJ
D003106:Colon / Q000473:pathology; D003110:Colonic Neoplasms / Q000150:complications / Q000473:pathology*; D005729:Ganglioneuroma / Q000150:complications / Q000473:pathology; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D007580:Jejunal Neoplasms / Q000150:complications / Q000473:pathology*; D007583:Jejunum / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications / Q000473:pathology*