Non-MHC determined resistance of Brown-Norway rats to develop experimental allergic encephalomyelitis is mediated by the endogenous production of transforming growth factor-beta.
D000818:Animals; D020296:Animals, Congenic; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000235:genetics* / Q000276:immunology*; D005260:Female; D017493:Leukocyte Common Antigens / Q000378:metabolism; D008285:Major Histocompatibility Complex; D008297:Male; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew; D013045:Species Specificity; D016176:T-Lymphocyte Subsets / Q000276:immunology; D016212:Transforming Growth Factor beta / Q000096:biosynthesis*