title: A cost-effectiveness comparison of surgical treatments for mitral valve disease.
abstract: This study compares the cost-effectiveness of mitral valve reconstruction and replacement. Published clinical data were used to determine the effectiveness of each procedure. Both direct and indirect costs were calculated. The findings indicate that reconstruction has lower costs per year of life extended than replacement due to better outcomes. Changing outcome probabilities and discount rates did not alter these results. Cost savings in excess of 40% may be achieved by early reconstruction for suitable patients. These results suggest that the prevailing practice of delaying surgery until replacement is needed should be reconsidered, especially for patients who could benefit from reconstruction.
mesh_terms: D003362:Cost-Benefit Analysis; D005069:Evaluation Studies as Topic; D006349:Heart Valve Diseases / Q000601:surgery; D006350:Heart Valve Prosthesis / Q000191:economics*; D006801:Humans; D008943:Mitral Valve / Q000601:surgery; D011183:Postoperative Complications / Q000191:economics; D012959:Socioeconomic Factors; D013673:Technology Assessment, Biomedical / Q000191:economics*; D014481:United States; D026712:Value of Life