Serum KL-6 level as a monitoring marker in a patient with pulmonary alveolar proteinosis.
A raised serum level of KL-6 is known to exist in active pulmonary fibrosis and KL-6 may be produced and secreted by type II pneumocytes. A case is described of pulmonary alveolar proteinosis with high serum KL-6 levels. The serum KL-6 level decreased after whole lung washing and correlated with symptoms, opacities on the chest radiograph, and arterial blood gas measurements. The serum KL-6 level may represent a useful marker for pulmonary alveolar proteinosis.
D000328:Adult; D000941:Antigens; D000951:Antigens, Neoplasm; D015415:Biomarkers / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D006023:Glycoproteins; D006801:Humans; D008297:Male; D018396:Mucin-1; D009077:Mucins; D010446:Peptide Fragments / Q000097:blood*; D011347:Procollagen / Q000097:blood*; D011649:Pulmonary Alveolar Proteinosis / Q000175:diagnosis*