[The reactions of the cat motor cortex neurons to electrical stimulation of the base of the forebrain as a conditioned signal for the reflex of placing the forelimb on a support].
Electrical stimulation of the globus pallidus (500 ms, 300 Hz) in the area restricted by the stereotaxic coordinates AP 14-AP 16, L5-L8 at the level of the anterior commissura (HO) evoked food reactions in the form of mouth opening, chewing, and licking in the absence of food. There were no visible motor effects in the case of electrical stimulation of the subcommissural area (H-2-H-4) corresponding to the ventral pallidum and substantia innominata. The conditioned forepaw placing reaction was elaborated with the basal forebrain stimulation used as a conditioned stimulus. After conditioning, the short (3-5 pulses) conditioned basal forebrain stimulation evoked a prolonged (up to 500-1000 ms) activation of neurons in the motor cortex. This activation did not change in the absence of the movement, i.e., after acute extinction of the contralateral forepaw placing or transfer of placing reaction to the ipsilateral forepaw.
D000818:Animals; D002415:Cats; D003214:Conditioning, Classical / Q000502:physiology*; D004558:Electric Stimulation / Q000379:methods; D005552:Forelimb / Q000502:physiology*; D009044:Motor Cortex / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D016548:Prosencephalon / Q000502:physiology*; D014851:Wakefulness / Q000502:physiology