[The influence of obesity on sexual development in pubertal children].
Serum testosterone and dehydroepiandrosterone sulfate (DHEAS) were measured in obesity and control groups using radioimmunoassay method (RIA). The sexual sign and sexual maturity were measured, too. The results showed that the contents of serum testosterone were 10.36 +/- 5.72 and (8.65 +/- 4.21) nmol/L in males of obesity and control groups respectively (P < 0.01). The levels of serum DHEAS were 8.25 +/- 6.47 and (5.63 +/- 4.98) pmol/L in femals of obesity and control groups, respectively. The length and beadth diameter of testis and length and surround of penis in males in obesity group were significantly higher than in control one (P < 0.01). The first spermatorrhea age of males in obesity group was significantly younger than that in control one (P < 0.01). Menarche age in females of obesity group and the second sexual sign development were earlier than that of control one (P < 0.01). It showed that sexual hormone, sexual development and sexual maturity were significantly higher and earlier in obesity group than those in control one.
D000293:Adolescent; D002648:Child; D019314:Dehydroepiandrosterone Sulfate / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000097:blood* / Q000503:physiopathology; D011897:Random Allocation; D012741:Sexual Maturation; D013739:Testosterone / Q000097:blood*