Long term neurological outcome of herpes encephalitis.
Twenty eight children with herpes simplex encephalitis were followed up for a mean of 5.5 years. Two children died and 26 survived, of whom 16 were left with no neurological sequelae and 10 had persistent neurological sequelae. Mean (SD) Glasgow coma score was significantly lower in the patients with neurological sequelae (7.7 (1.5)) and the patients who died (4.5 (0.7)), compared with the patients without neurological sequelae (11 (1.7)).
D000212:Acyclovir / Q000627:therapeutic use*; D000293:Adolescent; D000367:Age Factors; D000998:Antiviral Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D018792:Encephalitis, Viral / Q000150:complications / Q000188:drug therapy* / Q000821:virology; D005260:Female; D005500:Follow-Up Studies; D015600:Glasgow Coma Scale; D006561:Herpes Simplex / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008297:Male; D018139:Simplexvirus