The role of the target organ in cytokine-mediated beta-cell destruction. Possible relevance for the pathogenesis of insulin dependent diabetes mellitus.
D000595:Amino Acid Sequence; D000818:Animals; D016207:Cytokines / Q000096:biosynthesis / Q000502:physiology*; D003922:Diabetes Mellitus, Type 1 / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D004703:Endocrine System / Q000378:metabolism; D005609:Free Radicals; D006801:Humans; D007375:Interleukin-1 / Q000502:physiology; D007515:Islets of Langerhans / Q000378:metabolism / Q000473:pathology / Q000502:physiology*; D008969:Molecular Sequence Data; D009569:Nitric Oxide / Q000502:physiology; D051381:Rats