Single-cell measurements of ion concentrations within the intracellular parasite.
Rapid progress has been made in the study of intracellular ion activities of eukaryotic cells through the recent combination of high-resolution microscopy with fluorimetric ion-specific probes. This technique allows a specific ion concentration within a single living cell to be monitored on-line with high temporal and spatial resolution. In this report, Stefan Wünsch, Paul Horrocks, Michael Gekle and Michael Lanzer evaluate the application of single-cell fluorimetry to the study of transport processes in Plasmodium falciparum.
D000818:Animals; D001692:Biological Transport; D002414:Cations, Monovalent / Q000378:metabolism; D004912:Erythrocytes / Q000469:parasitology*; D005470:Fluorometry / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D010963:Plasmodium falciparum / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*