[Clinical study of combined Chinese herbal medicine with move stripe field radiation in treating primary hepatocellular carcinoma].
OBJECTIVE
To find a more effective treatment of primary hepatocellular carcinoma by using combined therapy of Chinese herbal medicine with radiotherapy.


METHODS
Prospective study was conducted with double-blind method on prognosis of patients treated with combined therapy of Xuefu Zhuyu decoction and move stripe field radiation on entire liver. A control group was established and treated with placebo and radiotherapy.


RESULTS
The 1-, 3- and 5-year survival rates of the test group were higher than those of the control group by 20.0%, 23.4% and 16.6% respectively. The remote metastatic rate of the two groups were not different significantly.


CONCLUSIONS
Xuefu Zhuyu decoction showed coordinative effect with radiotherapy on antitumor, it could enhance the radiosensitivity of liver cancer cells, increase the radiation tolerance of normal hepatocytes and reduce the side effect of radiotherapy.
D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004311:Double-Blind Method; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011867:Radioisotope Teletherapy / Q000379:methods; D011882:Radiotherapy, High-Energy