Mammalian nitric oxide synthases.
The nitric oxide (NO) synthase family of enzymes generate NO from L-arginine, which acts as a biologic effector molecule in a broad number of settings. This report summarizes some of the current information regarding NO synthase structure-function, reaction mechanism, control of catalysis, and protein interactions.
D000818:Animals; D001120:Arginine / Q000378:metabolism; D001880:Boranes / Q000737:chemistry; D002147:Calmodulin / Q000737:chemistry; D002384:Catalysis; D002417:Cattle; D008322:Mammals / Q000378:metabolism*; D051379:Mice; D009569:Nitric Oxide / Q000096:biosynthesis; D019001:Nitric Oxide Synthase / Q000737:chemistry* / Q000378:metabolism*; D052248:Nitric Oxide Synthase Type I; D052247:Nitric Oxide Synthase Type II; D052250:Nitric Oxide Synthase Type III; D051381:Rats; D015398:Signal Transduction; D013329:Structure-Activity Relationship