[A preliminary observation on effects of xiaochaihu decoction on uropathogenic E. coli].
OBJECTIVE
To study the effects of Xiaochaihu Decoction (XCHD) on uropathogenic E. coli (UEC).


METHODS
In vitro bacterial inhibition test and in vitro adhesion of UEC to human uro-epithelial cell assay were used to investigate the anti-infectionary effects of XCHD.


RESULTS
Proliferation inhibitory effect of E. Coli treated with XCHD, and a significant reduction in number of UEC to human uro-epithelial cells was observed in the XCHD treated group at a non-inhibitory concentration of the medication in comparison with the control groups.


CONCLUSIONS
It is possible that XCHD could act against urinary infection.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001422:Bacterial Adhesion / Q000187:drug effects*; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004847:Epithelial Cells / Q000382:microbiology; D004926:Escherichia coli / Q000254:growth & development / Q000502:physiology / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D014521:Urethra / Q000166:cytology*