Prediction and assessment of the response of Paget's disease to bisphosphonate treatment.
The rate of change of bone turnover either in response to treatment or its withdrawal taken in conjunction with fixed points in the disease cycle allows planning of treatment on an individual basis. This, in turn, helps to define the optimum scheduling of clinical visits to assess symptom response and to monitor disease activity.
D000469:Alkaline Phosphatase / Q000097:blood; D001862:Bone Resorption / Q000188:drug therapy / Q000517:prevention & control; D004164:Diphosphonates / Q000627:therapeutic use*; D012968:Etidronic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D006207:Half-Life; D006801:Humans; D010001:Osteitis Deformans / Q000188:drug therapy* / Q000201:enzymology / Q000473:pathology; D016032:Randomized Controlled Trials as Topic; D012008:Recurrence; D000068296:Risedronic Acid; D016896:Treatment Outcome