Genetic conflicts and the evolutionary origin of genomic imprinting.
In mammals, both paternally and maternally inherited copies of most genes are expressed. For a small number of genes, however, only the paternal copy is active, whereas in other cases only the maternal gene is transcribed. This form of nonmendelian expression, known as genomic imprinting, amounts to functional haploidy. The most intriguing explanation for why such a system should evolve when diploidy is omnipresent invokes conflicts between genetic interests of mothers, fathers and their offspring. Recent approaches to modelling the evolutionary origin of imprinting support this hypothesis but make different predictions about its prevalence and the likelihood of polymorphism.