Interference by aerobic and anaerobic bacteria in children with recurrent group A beta-hemolytic streptococcal tonsillitis.
OBJECTIVE
To compare the frequency of recovery of aerobic and anaerobic bacteria with interfering capability of group A beta-hemolytic streptococci (GABHS) in the tonsils of children with and without a history of recurrent GABHS pharyngotonsillitis.


METHODS
Tonsillar cultures were taken from a group of 20 children with and 20 without history of recurrent GABHS pharyngotonsillitis.


RESULTS
Eleven aerobic and anaerobic isolates with interfering capability with GABHS were recovered from 6 (30%) of the 20 children with recurrent GABHS, and 40 such organisms were isolated from 17 (85%) of the 20 without recurrences (P<.01). The interfering organisms included aerobic (alpha-hemolytic and nonhemolytic streptococci) and anaerobic organisms (Prevotella and Peptostreptococcus species).


CONCLUSIONS
The tonsils of children with a history of recurrent GABHS infection contain fewer aerobic and anaerobic bacteria with interfering capability of GABHS than those without the history of recurrent GABHS infection. The presence of these interfering bacteria may play a role in preventing GABHS infection.
D000293:Adolescent; D000898:Antibiosis; D001420:Bacteria, Aerobic / Q000502:physiology*; D001421:Bacteria, Anaerobic / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009960:Oropharynx / Q000382:microbiology*; D010462:Peptostreptococcus / Q000302:isolation & purification / Q000502:physiology; D018720:Prevotella / Q000302:isolation & purification / Q000502:physiology; D012008:Recurrence; D013290:Streptococcal Infections / Q000503:physiopathology*; D013297:Streptococcus pyogenes / Q000302:isolation & purification; D014069:Tonsillitis / Q000382:microbiology*