[Clinical observation on treatment of infantile cholestatic hepatitis syndrome by rhubarb].
OBJECTIVE
To evaluate the role of Rhubarb in treating infantile cholestatic hepatitis syndrome (IHS).


METHODS
Forty-four patients of the treatment group were treated with Rhubarb per os and/or duodenal infusion, 20 cases of the control group were treated with general liver protecting therapy such as inosine, vitamin C and glucose. Serum bilirubin, alanine transaminase (ALT) and gamma-glutamyl transferase (gamma-GT) level, bilirubin in duodenal juice and liver size were observed before and after treatment.


RESULTS
In the treatment group, 18 cases were markedly effective, 21 effective, 3 ineffective and 2 were deteriorated, while in the control group, the respective number were 0, 4, 13 and 3.


CONCLUSIONS
Rhubarb was a markedly effective in cholagoging and abating of jaundice, it could promote the recovery of liver function, dredge the cholestasis in cholangiole and micro-cholangiole so as to promote the bile secretion.
D002779:Cholestasis / Q000188:drug therapy* / Q000209:etiology; D003587:Cytomegalovirus; D003586:Cytomegalovirus Infections / Q000188:drug therapy; D005260:Female; D006525:Hepatitis, Viral, Human / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008297:Male; D008517:Phytotherapy; D010946:Plants, Medicinal; D012250:Rheum / Q000627:therapeutic use*; D013577:Syndrome