title: The dependence of catalytic activities of secondary functional beta-cyclodextrins on cavity structures.
abstract: Secondary imidazole-appended beta-cyclodextrin 5 with a nondistorted cavity synthesized from a novel intermediate 3-amino-3-deoxy-beta-cyclodextrin exhibits much greater catalytic activity in the ester hydrolysis than its isomer 6 with a distorted cavity, indicating that the catalytic activities of secondary functional cyclodextrins are dependent on cavity structures.
mesh_terms: D002384:Catalysis; D003505:Cyclodextrins / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology*; D006868:Hydrolysis; D007700:Kinetics; D013329:Structure-Activity Relationship; D047392:beta-Cyclodextrins