title: Potential antimicrobial agents--I: Structural modifications and antimicrobial activity of some isatin derivatives.
abstract: New isatin-3-isonicotinylhydrazones, isatinazine and its Mannich bases and spiro (indoline-3, 2'-thiadiazoline)-2-one have been synthesized. These compounds have been screened for their antibacterial activity against the Gram-positive and Gram-negative bacteria.
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D007510:Isatin / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests