title: [Investigation on the epidemiology of Histoplasma capsulatum infection in Nanjing district].
abstract: Two hundred and ninety-two permanent or temporary residents in Nanjing district were tested with histoplasmin (Histolyn-CYL, ALK/Berkeley Laboratories, USA) and PPD. Forty-nine (16.78%) subjects reacted to histoplasmin with 5.0-23.0 (9.5 +/- 4.2) mm induration. Positive reaction rate among people without pulmonary diseases (normal group) was 15.10% comparing to 17.74% to patients with pulmonary diseases. Positive reaction to PPD with 5-50 (14.2 +/- 4.7) mm induration was 56.16%, with 59.43% in normal group and 54.30% in patients with pulmonary diseases while 8.90% subjects reacted to both histoplasmin and PPD, 7.88% of the research subjects reacted to histoplasmin but not to PPD. Result suggested that there was herd infection of Histoplasma capsulatum in Nanjing district.
mesh_terms: D000328:Adult; D002681:China / Q000453:epidemiology; D005260:Female; D006659:Histoplasmin / Q000276:immunology; D006660:Histoplasmosis / Q000453:epidemiology*; D006801:Humans; D008297:Male; D015995:Prevalence; D012882:Skin Tests