Long-term histopathologic findings in two cerebral aneurysms embolized with Guglielmi detachable coils.
We present gross pathologic autopsy findings of a patient who was treated for two aneurysms with Guglielmi detachable coils (GDCs), and who died 33 months after the procedure. Histologic findings are also presented. In both aneurysms, the coils were firmly attached to the aneurysmal wall, making it impossible to remove them from the sac. The ostium of one aneurysm was covered by collagenous tissue and a single layer of endothelium.
D000328:Adult; D000783:Aneurysm / Q000473:pathology / Q000628:therapy; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000473:pathology; D003094:Collagen; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D004730:Endothelium, Vascular / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D008137:Longitudinal Studies; D009880:Ophthalmic Artery / Q000473:pathology; D013499:Surface Properties