title: Increased accuracy of echocardiographic measurement of flow using automated spherical integration of multiple plane velocity vectors.
abstract: The calculation of blood flow in the heart by surface integration of velocity vectors (SIVV) using Doppler ultrasound is independent of the angle. Flow is normally calculated from velocity in a spherical thick shell with its center located at the ultrasound transducer. In a numerical simulation, we have shown that the ratio between minor and major axes of an elliptic flow area substantially influences the accuracy of the estimation of flow in a single scan plane. The accuracy of flow measurements by SIVV can be improved by calculating the mean of the values from more than one scan plane. We have produced an automated computer program that includes an antialiasing procedure. We confirmed an improvement of flow measurements in a pulsatile hydraulic flow model, the 95% confidence interval for single estimations being reduced from 20% to 10% (p < 0.05) using the newly developed software. We think that the SIVV method has important implications for clinical transthoracic echocardiography.
mesh_terms: D000465:Algorithms; D001783:Blood Flow Velocity; D015150:Echocardiography, Doppler / Q000379:methods*; D006801:Humans; D008432:Mathematical Computing; D008955:Models, Cardiovascular; D011673:Pulsatile Flow; D013318:Stroke Volume / Q000502:physiology