Atrioventricular septal defect with separate right and left atrioventricular valvar orifices in a patient with foetal hydantoin syndrome.
The teratogenic properties of phenytoin, including cardiac malformations, have been previously documented. We report one patient with foetal hydantoin syndrome and atrioventricular septal defect with common atrioventricular junction but separate right and left atrioventricular valves, an association that has not been described, to the best of our knowledge.
D000014:Abnormalities, Drug-Induced / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects*; D006328:Cardiac Catheterization; D015150:Echocardiography, Doppler; D004827:Epilepsy / Q000188:drug therapy; D005260:Female; D005315:Fetal Diseases / Q000139:chemically induced*; D005500:Follow-Up Studies; D006344:Heart Septal Defects, Atrial / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D006345:Heart Septal Defects, Ventricular / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D010672:Phenytoin / Q000008:administration & dosage / Q000009:adverse effects*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D013577:Syndrome