title: Synchronous appearance of keratoacanthomas in burn scar and skin graft donor site shortly after injury.
abstract: Skin malignancies can originate in burn scars (Marjolin's ulcer). The most common is squamous cell carcinoma, usually appearing years after injury. Split-thickness skin graft donor sites as a source of malignant transformation are far less frequent and demonstrate a shorter interval between surgery and tumor onset. Keratoacanthomas have rarely been reported to arise in such scars. We describe the simultaneous occurrence of keratoacanthomas on a spontaneously healed second-degree burn on the flank and in the scar of a skin graft donor site on the thigh, 4 months after a 40% total body surface area burn.
mesh_terms: D002056:Burns / Q000150:complications*; D002921:Cicatrix / Q000150:complications*; D020405:Dermis / Q000473:pathology; D004804:Eosinophils / Q000473:pathology; D004817:Epidermis / Q000473:pathology; D005355:Fibrosis; D006801:Humans; D007633:Keratins / Q000032:analysis; D007636:Keratoacanthoma / Q000209:etiology* / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016038:Skin Transplantation / Q000009:adverse effects*