title: Validation of the diagnostic criteria for atopic dermatitis.
abstract: OBJECTIVE
  To validate the accuracy of newly proposed diagnostic criteria for atopic dermatitis (AD).
  
  
  METHODS
  Double-blind, cross-sectional study comparing the achievement of new criteria with the diagnosis of a dermatologist.
  
  
  METHODS
  A private, general dermatology, outpatient clinic.
  
  
  METHODS
  A sample of 416 consecutive patients attending the clinic within 2 months (146 males and 270 females), consisting of 60 patients with AD and 356 control patients with other skin diseases.
  
  
  METHODS
  Sensitivity, specificity, and positive and negative predictive values of proposed criteria in the diagnosis of AD.
  
  
  RESULTS
  Sensitivity, specificity, and positive and negative predictive values of proposed diagnostic criteria for AD were 10.0% (95% confidence interval [CI], 4.1%-21.2%), 98.3% (95% CI, 96.2%-99.3%), 50.0% (95% CI, 22.3%-77.7%), and 86.6% (95% CI, 82.8%-89.7%), respectively.
  
  
  CONCLUSIONS
  These diagnostic criteria for AD are highly specific and are suitable for clinical trials. However, they may not achieve enough sensitivity to be useful for large, population-based epidemiological studies or for routine clinical practice, at least in Iran.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D003876:Dermatitis, Atopic / Q000175:diagnosis*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity