[The effect of arsenic on reproduction and offspring development of rats].
The effect of arsenic on reproduction and offspring development of Wistar rats was studied. The results demonstrated that the pregnant rate and feeding survival rate in high dose group were lower than these of in the groups of control and low dose. The differences of normal parturition rate and the survival rate in all the groups were not significant. The contents of arsenic in the young rats were increased by the doses of arsenic and the differences were significant. After 10, 20 and 30 days of birth, the weight of offspring in high dose group was lighter than that in the groups of control and low dose. According to the results, arsenic can affect the reproduction of rats and the development of their offspring.
D000818:Animals; D000831:Animals, Newborn; D020261:Arsenic Poisoning; D000077237:Arsenic Trioxide; D001152:Arsenicals; D005314:Embryonic and Fetal Development / Q000187:drug effects*; D005260:Female; D005298:Fertility / Q000187:drug effects*; D008297:Male; D010087:Oxides / Q000633:toxicity*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D017208:Rats, Wistar