title: Induced endothelial cell loss in phacoemulsification using topical anesthesia plus intracameral lidocaine.
abstract: OBJECTIVE
  To determine whether lidocaine 1% injected into the anterior chamber during phacoemulsification damaged the corneal endothelium.
  
  
  METHODS
  Ophthalmology Service, University Hospital, San Juan de Alicante, Spain.
  
  
  METHODS
  In 19 eyes of 19 patients, small incision phacoemulsification and foldable lens (AcrySof MA60BM) implantation was performed using topical anesthesia supplemented by lidocaine 1% (0.3 mL) in the anterior chamber. All cases were operated by the same surgeon. Specular microscopy was performed before surgery and 1 and 3 months postoperatively.
  
  
  RESULTS
  Mean endothelial cell loss was 5.41% +/- 8.50 (SD) at 1 month and 5.93 +/- 8.50% at 3 months.
  
  
  CONCLUSIONS
  The endothelial damage was similar to that described by other authors, suggesting that phacoemulsification surgery can be performed successfully using topical anesthesia supplemented by lidocaine 1% in the anterior chamber.
mesh_terms: D000368:Aged; D000772:Anesthesia, Local / Q000009:adverse effects*; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects*; D002452:Cell Count; D003316:Corneal Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology; D004728:Endothelium, Corneal / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008012:Lidocaine / Q000008:administration & dosage / Q000009:adverse effects*; D009883:Ophthalmic Solutions; D018918:Phacoemulsification; D014463:Ultrasonography