Vitamin E suppresses cyclosporine A-induced increase in the urinary excretion of arachidonic acid metabolites including F2-isoprostanes in the rat model.
D000818:Animals; D016718:Arachidonic Acid / Q000378:metabolism / Q000652:urine*; D003404:Creatinine / Q000378:metabolism; D016572:Cyclosporine / Q000037:antagonists & inhibitors* / Q000633:toxicity*; D015237:Dinoprost / Q000652:urine; D005609:Free Radicals / Q000378:metabolism; D007166:Immunosuppressive Agents / Q000037:antagonists & inhibitors* / Q000633:toxicity*; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D009392:Nephrectomy; D011460:Prostaglandins F / Q000652:urine; D051381:Rats; D017207:Rats, Sprague-Dawley; D013929:Thromboxane B2 / Q000652:urine; D014810:Vitamin E / Q000494:pharmacology*