[Clinical study on treatment of chronic aplastic anemia with busui shengxue capsule].
OBJECTIVE
To explore into the theoretical basis of Busui Shengxue Capsule (BSSXC) in treating chronic aplastic anemia (CAA).


METHODS
Applying the techniques of cell culture and FACS to observe the bone marrow mononuclear, cells of 35 cases CAA before and after treatment.


RESULTS
(1) BSSXC has the function of restoring the membrane receptors of IL-3, IL-6, IL-11 of hematopoietic stem cell. (2) The treatment effect of BSSXC is better than Western medicine. (3) In treatment group, to stimulate the hematopolietic stem cell with IL-3, IL-6, IL-11, the rate of cell colony forming unit and CD34+ cell were obviously different between Yang Deficiency type and Yin Deficiency type before treatment (P < 0.05). After treatment the difference between these two types was also obvious (P < 0.05).


CONCLUSIONS
BSSXC could improve the membrane receptor of hematopoietic stem cell acted by hematopoietic stimulating factors.
D000293:Adolescent; D000328:Adult; D000741:Anemia, Aplastic / Q000188:drug therapy* / Q000473:pathology; D018952:Antigens, CD34 / Q000378:metabolism; D001854:Bone Marrow Cells / Q000276:immunology; D002214:Capsules; D002478:Cells, Cultured; D002648:Child; D002908:Chronic Disease; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged