title: Digestion of starch and glycaemic response to mixed meals in pigs.
abstract: The digestion in the proximal intestine of mixed meals (5,160 kJ) containing either native (NS) or pregelatinized (PS) maize starches (approximately 200 g), and the postprandial glycaemic responses they induced were compared in pigs. For both meals, approximately 25% of the ingested starch was assimilated above the duodenal cannula (positioned 75 cm beyond the pylorus). Larger amounts of starch were collected for NS than for PS during the first 30 min. The glycaemic responses, however, indicated a higher rate of glucose absorption for PS during the first 30 min, which could be explained by the higher susceptibility of PS to hydrolysis, as we observed in vivo. Indeed, malto-oligosaccharides (G1-G3) represented almost 80% of the total alpha-glucans collected at 150 min in the duodenum after the PS meal. At that time, after the NS meal, only 30% of the alpha-glucans were malto-oligosaccharides. Thus, even after a mixed meal, the starch digestion rate can alter the observed postprandial glycaemic response.
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D004063:Digestion; D004386:Duodenum / Q000378:metabolism; D005260:Female; D005502:Food; D006868:Hydrolysis; D007328:Insulin / Q000097:blood; D007413:Intestinal Mucosa / Q000378:metabolism; D008320:Maltose / Q000378:metabolism; D009844:Oligosaccharides / Q000378:metabolism; D009994:Osmolar Concentration; D013213:Starch / Q000378:metabolism*; D013552:Swine / Q000502:physiology*; D003313:Zea mays; D000516:alpha-Amylases / Q000378:metabolism