title: Heterozygote advantage of the MTHFR gene in patients with neural-tube defect and their relatives.
mesh_terms: D000022:Abortion, Spontaneous / Q000235:genetics; D000483:Alleles; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation / Q000235:genetics; D005838:Genotype; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D008297:Male; D045102:Methylenetetrahydrofolate Dehydrogenase (NAD+); D009154:Mutation / Q000235:genetics; D009436:Neural Tube Defects / Q000201:enzymology / Q000235:genetics*; D010088:Oxidoreductases / Q000235:genetics*; D011247:Pregnancy; D012737:Sex Factors; D016135:Spinal Dysraphism / Q000201:enzymology / Q000235:genetics