[The effects of high dietary zinc on alloxan induced diabetic mice].
The effects of high dietary zinc on alloxan induced diabetic mice were studied. The results showed that high zinc could sharply decrease the body weight and increase food intake, water intake and urine of diabetic mice, and increase blood sugar levels in diabetic mice. After alloxan injection in diabetic model group, urine sugar levels reached [symbol: see text] at the 2nd day and [symbol: see text] at the 6th day. After alloxan injection in high-zinc-diabetic mice group, urine sugar levels reached [symbol: see text] and [symbol: see text] at the 2nd and the 4th day, respectively. These results suggested that the high level of dietary zinc may be damage to diabetic patients.
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy*; D008297:Male; D051379:Mice; D015032:Zinc / Q000008:administration & dosage / Q000009:adverse effects*