title: Histological evaluation of repair using a bioresorbable membrane beneath a resin-modified glass ionomer after mechanical furcation perforation in dogs' teeth.
abstract: Resorbable barriers have been shown both clinically and histologically to produce favorable periodontal regenerative outcomes. The purpose of the present study was to evaluate the histological response to one such resorbable barrier (Atrisorb) when used as a matrix under a resin-modified glass ionomer (RMGI) sealant in the repair of furcation perforations in experimental animals. After anesthesia, pulp extirpation and filling of radicular canals with zinc oxide-eugenol cement, furcal perforations were made in 30 lower premolar (P2, P3, and P4) teeth of labrador dogs with a 1 mm diameter round bur in a conventional handpiece. The perforated teeth were randomly divided into two groups of 15 teeth. Group 1 teeth were treated with RMGI alone and group 2 with the resorbable barrier under RMGI. Six teeth without perforations served as negative controls. Pulp chambers of all teeth were filled with RMGI cement. Animals were sacrificed after 3 months. The teeth and the surrounding structures were processed for light microscopy. There were no differences found between results for glass ionomer alone and barrier with glass ionomer. The conclusion of this study is that placement of a resorbable barrier at the pulp chamber aspect of a furcation perforation did not result in superior healing, compared with the use of resin-modified glass ionomer alone.
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D001641:Bicuspid / Q000293:injuries; D016009:Chi-Square Distribution; D004285:Dogs; D005069:Evaluation Studies as Topic; D005899:Glass Ionomer Cements; D016557:Guided Tissue Regeneration, Periodontal; D019344:Lactic Acid; D016018:Least-Squares Analysis; D008567:Membranes, Artificial; D010519:Periodontium / Q000502:physiology; D011091:Polyesters; D011108:Polymers; D012117:Resins, Synthetic; D012390:Root Canal Therapy; D018709:Statistics, Nonparametric; D018677:Tooth Injuries / Q000628:therapy*; D014092:Tooth Root / Q000293:injuries*; D014945:Wound Healing