[Treatment of severe cholestatic hepatitis by integrated traditional Chinese and Western medicine].
OBJECTIVE
To study the curative effect of Chinese medicine in treating severe cholestatic-hepatitis (SCH).


METHODS
Three hundred and fifty patients of SCH with total bilirubin level > or = 171 mumol/L were treated with Chinese medicines. For those with Blood Stasis Syndrome, treated with the recipe mainly consisted of Radix Paeoniae Rubra, and for which accompanied with blood Heat, fluid retention in epigastric region. Dampness dissenubated in Sanjiao ([symbol: see text]) or both Spleen and Kidney Yang-Deficiency Syndrome, the recipe was used in modification according to the Syndrome.


RESULTS
Treatment was markedly effective in 288 cases and effective in 26 cases, the total effective rate being 89.7%.


CONCLUSIONS
It is difficult in treating severe cholestatic hepatitis, especially the chronic cholestatic hepatitis, which could develop to severe chronic hepatitis if the jaundice lasted for a long time. This study showed a good effect of Chinese herbal medicine in eliminating jaundice.
D000293:Adolescent; D000328:Adult; D002780:Cholestasis, Intrahepatic / Q000188:drug therapy* / Q000821:virology; D003937:Diagnosis, Differential; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D019694:Hepatitis B, Chronic / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged