title: Abruptio placentae and chorioamnionitis-microbiological and histologic correlation.
abstract: BACKGROUND
  To determine the association of chorioamnionitis with placental abruption.
  
  
  METHODS
  Fifty pregnant women admitted with abruptio placentae were compared to an equally large control group in spontaneous labor with no history of antepartum hemorrhage. Swabs from the cervix and placental membranes were cultured for aerobic and anaerobic organisms. Placental membranes were studied histologically in 40 women of study group and 35 of control group for any evidence of chorioamnionitis.
  
  
  RESULTS
  Specific organisms were isolated in 22 (44%) women in the study group and 19 (38%) women in the control group. The cervical swab microbiological flora was similar in both groups but isolation of specific organisms from placental membrane culture was higher in the study group (40%) compared to the controls (18% p<0.05). Evidence of histologic chorioamnionitis was higher in the study group 12/40 (30%), than in the control group 8/35 (22.85%), but the difference was not significant.
  
  
  CONCLUSIONS
  The incidence of silent chorioamnionitis (placental membrane culture positivity) is higher in the abruptio placentae.
mesh_terms: D000037:Abruptio Placentae / Q000150:complications* / Q000382:microbiology / Q000473:pathology; D000328:Adult; D001419:Bacteria / Q000302:isolation & purification; D016022:Case-Control Studies; D002584:Cervix Uteri / Q000382:microbiology; D002821:Chorioamnionitis / Q000150:complications* / Q000382:microbiology / Q000473:pathology; D005260:Female; D006801:Humans; D010920:Placenta / Q000382:microbiology; D011247:Pregnancy; D011446:Prospective Studies