Pharmacology of anthelmintic resistance.
Anthelmintic resistance has grown from a curiosity to an important economic problem in several animal industries and is now set to threaten the control of human parasites. The pharmacology of anthelmintics and anthelmintic resistance has been studied most extensively in the nematode parasites of sheep. Here, Nick Sangster and Jenny Gill discuss this veterinary experience, summarizing the progress made in understanding anthelmintic resistance and highlighting the tools available for research.
D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology* / Q000627:therapeutic use; D001562:Benzimidazoles / Q000494:pharmacology / Q000627:therapeutic use; D002417:Cattle; D004351:Drug Resistance; D006188:Haemonchiasis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D006189:Haemonchus / Q000187:drug effects*; D006736:Horses; D006801:Humans; D007559:Ivermectin / Q000031:analogs & derivatives / Q000494:pharmacology / Q000627:therapeutic use; D007978:Levamisole / Q000494:pharmacology / Q000627:therapeutic use; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy / Q000469:parasitology*; D013552:Swine; D014252:Trichostrongyloidiasis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D014254:Trichostrongylus / Q000187:drug effects*