title: A histopathological study of the effects of pulsed Nd:YAG laser irradiation on infected root canals in dogs.
abstract: The effects of pulsed Nd:YAG laser irradiation during root canal treatment of infected teeth were investigated histopathologically in dogs. One hundred and eight teeth with a single root in 15 healthy adult beagle strain dogs were used in this study. After inducing infected teeth, each root canal was shaped with up to at least a #40 K-file; then, after coating with black ink, the canal was irradiated using the following parameters: 1 W, 30 pps, for 1 and 2 s, and 2 W, 30 pps, for 2 s. The degree of inflammation of the periapical regions at 2, 4, and 8 wk was examined histopathologically by light microscopy. Inflammation of the periapical regions in the laser-treated groups was significantly less than that in the control group at 4 and 8 wk (p < 0.05). These results suggest that pulsed Nd:YAG laser is useful for root canal treatment of infected teeth, if appropriate parameters are selected.
mesh_terms: D000818:Animals; D001421:Bacteria, Anaerobic / Q000528:radiation effects; D016009:Chi-Square Distribution; D003786:Dental Pulp Cavity / Q000382:microbiology* / Q000473:pathology / Q000528:radiation effects*; D004285:Dogs; D005069:Evaluation Studies as Topic; D053685:Laser Therapy; D009354:Neodymium; D010485:Periapical Periodontitis / Q000517:prevention & control*; D012390:Root Canal Therapy / Q000295:instrumentation* / Q000379:methods; D016037:Single-Blind Method; D014945:Wound Healing