Photosensitivity due to alprazolam with positive oral photochallenge test after 17 days administration.
We describe a 65-year-old male patient with photosensitivity due to alprazolam. A photopatch test was negative. An oral photochallenge test after taking alprazolam for 17 days with UVA irradiation was positive. Alprazolam, a lipid-soluble drug, may require long duration of administration to cause photosensitivity.
D000284:Administration, Oral; D000368:Aged; D000525:Alprazolam / Q000009:adverse effects*; D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D004890:Erythema / Q000139:chemically induced; D006801:Humans; D008297:Male; D010328:Patch Tests; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects