Synchronous appearance of keratoacanthomas in burn scar and skin graft donor site shortly after injury.
Skin malignancies can originate in burn scars (Marjolin's ulcer). The most common is squamous cell carcinoma, usually appearing years after injury. Split-thickness skin graft donor sites as a source of malignant transformation are far less frequent and demonstrate a shorter interval between surgery and tumor onset. Keratoacanthomas have rarely been reported to arise in such scars. We describe the simultaneous occurrence of keratoacanthomas on a spontaneously healed second-degree burn on the flank and in the scar of a skin graft donor site on the thigh, 4 months after a 40% total body surface area burn.
D002056:Burns / Q000150:complications*; D002921:Cicatrix / Q000150:complications*; D020405:Dermis / Q000473:pathology; D004804:Eosinophils / Q000473:pathology; D004817:Epidermis / Q000473:pathology; D005355:Fibrosis; D006801:Humans; D007633:Keratins / Q000032:analysis; D007636:Keratoacanthoma / Q000209:etiology* / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016038:Skin Transplantation / Q000009:adverse effects*