[Effect of tongxinluo capsule on experimental myocardial ischemia, arrhythmia and hyperlipidemia].
OBJECTIVE
To study the effects of Tongxinluo capsule (TXLC) on experimental myocardial ischemia and infarction, arrhythmia and hyperlipidemia.


METHODS
Using the methods of epicardial mapping and NBT-ink double staining and the ratio of tissue in myocardial infarction in which the anterior coronary artery was ligated in anesthetized dogs, acute myocardial ischemia was induced with pituitrin and hyperlipidemia was induced with feeding high lipid diet in rats, arrhythmia was induced with chloroform in mice.


RESULTS
The TXLC reduced significantly the myocardial ischemic limits, degree and the myocardial infarction area, inhibited obviously the ocurrence of arrhythmia and reduced the level of hyperlipidemia.


CONCLUSIONS
The TXLC could improve significantly the myocardial ischemia mycardial infarction and prevent obviously the ocurrence of arrhythmia and hyperlipidemia.
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000517:prevention & control*; D004285:Dogs; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006949:Hyperlipidemias / Q000517:prevention & control*; D008297:Male; D008419:Materia Medica / Q000627:therapeutic use; D051379:Mice; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000473:pathology; D017202:Myocardial Ischemia / Q000188:drug therapy*; D009206:Myocardium / Q000473:pathology; D051381:Rats