[A study on efficacy of rabies vaccine prepared by primary hamster kidney cells in Guangxi].
OBJECTIVE
To study the efficacy of post-exposure use of concentrated rabies vaccine prepared by primary hamster kidney cells during the past 16 years (1980-1995) in the Guangxi Zhuang Autonomous Region and the role of ambulant care for the victims injured by dog-bite.


METHODS
Data of rabies incidence notified from all the prefectures and cities in Guangxi were summarized and corroborated, field studies were conducted and rabies antibodies were determined.


RESULTS
Incidence of rabies fell to 0.04 per ten thousand in 1995 from 2.46 per ten thousand in 1981 with increased use of post-exposure rabies immunization with concentrated vaccine and in-time treatment for dog-bite wounds in the widespread ambulant care settings.


CONCLUSIONS
Rabies vaccine prepared by primary hamster kidney cells has good efficacy in protection from rabies and early and in-time treatment for dog-bite wounds could enhance their protective effects. It is suggested that concentrated vaccine be purified to avoid adverse effects caused by its allergen.
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002681:China / Q000453:epidemiology; D006224:Cricetinae; D006801:Humans; D015994:Incidence; D007668:Kidney / Q000166:cytology; D051379:Mice; D011818:Rabies / Q000453:epidemiology / Q000517:prevention & control*; D011819:Rabies Vaccines / Q000276:immunology*; D011820:Rabies virus / Q000276:immunology*