Auxiliary liver transplantation in acute liver failure in the rat -- an illustrated description of a new surgical approach.
BACKGROUND
To investigate auxiliary liver transplantation successfully in rats suffering from acute liver failure, we developed a new surgical approach.


METHODS
A 70% hepatectomized liver graft was implanted into the right upper quadrant of the abdomen. The donor portal vein was anastomosed with the recipient's right renal artery using the splint technique. The donor infrahepatic vena cava was attached onto the recipient vena cava end to side. The bile duct was implanted into the duodenum.
D000714:Anastomosis, Surgical / Q000009:adverse effects / Q000379:methods; D000818:Animals; D001646:Bile; D004195:Disease Models, Animal; D004386:Duodenum / Q000601:surgery; D006085:Graft Survival; D006498:Hepatectomy / Q000379:methods; D006500:Hepatic Duct, Common / Q000637:transplantation; D017114:Liver Failure, Acute / Q000601:surgery*; D016031:Liver Transplantation / Q000009:adverse effects / Q000379:methods*; D008297:Male; D010538:Peritonitis / Q000209:etiology; D011169:Portal Vein / Q000637:transplantation; D051381:Rats; D011917:Rats, Inbred Lew; D012077:Renal Artery / Q000601:surgery; D013165:Splints; D015996:Survival Rate; D014185:Transplantation, Isogeneic; D014682:Vena Cava, Inferior / Q000637:transplantation