Biodiversity and bioseparation of HIV-1 envelope glycoproteins.
Since 1984, studies from almost every branch of modern biology have filled in many gaps in our knowledge of human immunodeficiency virus type 1 (HIV-1). This review focuses on studies of biodiversity and bioseparation of HIV-1 envelope glycoproteins from the vaccine development point of view. It presents an updated picture of different systems for producing either native or recombinant HIV-1 envelope glycoproteins for the preparation of vaccine candidates. The prevention of HIV-1-associated disease is highly relevant to the abrogation of the neoplastic processes associated with this pathogen.
D016915:AIDS Vaccines; D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000276:immunology; D000818:Animals; D015686:Gene Products, env / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D015752:Genes, env; D014644:Genetic Variation; D015699:HIV Envelope Protein gp120 / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D015497:HIV-1 / Q000235:genetics* / Q000276:immunology; D006801:Humans; D017720:Molecular Epidemiology; D019707:Receptors, Chemokine / Q000502:physiology