title: Involuntary weight loss and the nonhealing wound: the role of anabolic agents.
abstract: Endocrine responses to trauma result in a net catabolic state and exaggerated hepatic gluconeogenesis, with losses in lean body mass that can compromise wound healing. With proper nutrition, reduction of stress, resistance exercise, and the addition of certain anabolic agents, lean body mass can be restored and wound healing promoted.
mesh_terms: D045930:Anabolic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D005081:Exercise Therapy; D006801:Humans; D018529:Nutritional Support; D015431:Weight Loss / Q000187:drug effects* / Q000502:physiology*; D014945:Wound Healing / Q000187:drug effects* / Q000502:physiology*; D014947:Wounds and Injuries / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism