title: Disc hemorrhage and peripapillary atrophy in apparently healthy subjects.
abstract: OBJECTIVE
  We estimated the prevalence of disc hemorrhage and peripapillary atrophy in apparently healthy subjects.
  
  
  METHODS
  We reviewed consecutive plain color fundus photographs of 12,140 eyes of 6,070 subjects (male/female=4,079/1,991) who visited a health consultation center.
  
  
  RESULTS
  We analyzed 11,934 eyes of 5,967 subjects with good quality of photographs. Disc hemorrhage was found in 36 eyes of 35 subjects (0.6%). The prevalence of disc hemorrhage was significantly greater in women 60 years of age or older (Fisher's exact test, p=0.0004). The prevalence of peripapillary atrophy (zone Beta, zone Alpha), and suspected glaucomatous excavation in eyes with disc hemorrhage was 66.7%, 86.1% and 25.0%, respectively, and significantly greater than that (29.1%, 52.9% and 1.7%) in eyes without disc hemorrhage (Fisher's exact test, p<0.0001).
  
  
  CONCLUSIONS
  Disc hemorrhage is more frequent in women over 60 years of age and is significantly associated with peripapillary atrophy in otherwise apparently healthy Japanese people.
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005654:Fundus Oculi; D005901:Glaucoma / Q000150:complications; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009896:Optic Atrophy / Q000453:epidemiology* / Q000209:etiology; D009898:Optic Disk / Q000098:blood supply*; D010781:Photography; D015995:Prevalence; D012166:Retinal Hemorrhage / Q000453:epidemiology* / Q000209:etiology; D017678:Sex Distribution; D015351:Vision Screening