[Analysis on the immuno-effects of two different Japanese encephalitis virus vaccines].
319 infants aged 5-18 months were divided in to 2 groups and immunized with Japanese encephalitis virus inactivated vaccine and live attenuated vaccine respectively. Under the detection of serum antibody, a 3.76% serum antibody positive rate was revealed before the immunization. However, after the basic immunization the serum positive rates of the two vaccines reached 59.56% and 56.08% respectively but still under the protective level. The infants were then given booster injection one year later. The serum positive rates reached 94.62% and 98.21% respectively 1 month later. When six months after the booster immunization, the positive rates were 72.34% and 94.74% respectively. According to the results, the following immunization order was recommend. For inactivated vaccine: 2 injections are given with an interval of 7-10 days for basic immunization and booster immunization be given in the second and third years. For live attenuated vaccine: one injection is given for basic immunization then booster dose be given in the second year and 4-5 years later.
D000914:Antibodies, Viral / Q000097:blood*; D018349:Encephalitis Viruses, Japanese / Q000276:immunology; D004672:Encephalitis, Japanese / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007117:Immunization, Secondary; D007223:Infant; D008297:Male; D014611:Vaccination / Q000379:methods; D014613:Vaccines, Attenuated / Q000276:immunology*; D015164:Vaccines, Inactivated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology