The variability of syphilitic chancres.
Sixty-four patients who had darkfield microscopic evidence of primary syphilis underwent a standardized interview and physical examination. Two or more lesions were observed in 47% of patients, 7.8% of patients had non-indurated ulcers, and the borders of the ulcers of 7.8% were irregular and slightly undermined, suggesting lesions of chancroid. Only 27 patients (42.7%) had single, indurated chancres with regional lymphadenopathy. It is suggested that the "classic" chancre may be the "atypical" lesion.
D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D002601:Chancre / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006561:Herpes Simplex / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010808:Physical Examination; D018139:Simplexvirus / Q000276:immunology / Q000302:isolation & purification; D013588:Syphilis Serodiagnosis; D014210:Treponema pallidum / Q000276:immunology