[Radiologic anomalies of pseudohypoparathyroidism: diagnostic importance].
Pseudohypoparathyroidism is a congenital metabolic disorder which is often revealed by growth retardation. The diagnosis may be suggested by plain radiological findings such as short metacarpals, mainly the fourth, epiphyseal anomalies or subcutaneous calcifications. The following biological tests are mandatory to confirm this diagnosis: CaP workup and plasma level of PTH; urine cAMP measurement after PTH challenge; Evaluation of protein Gs activity In this study of 20 cases displays will be reviewed the different radiological findings seen in patients with PsHP and the relative value discussed, such as narrowing of the spinal canal and presence of bony findings of hyperparathyroidism.
D000293:Adolescent; D000328:Adult; D015519:Bone Density; D001927:Brain Diseases / Q000000981:diagnostic imaging; D002114:Calcinosis / Q000000981:diagnostic imaging; D002130:Calcium Phosphates / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D000242:Cyclic AMP / Q000652:urine; D004838:Epiphyses / Q000000981:diagnostic imaging; D005260:Female; D019204:GTP-Binding Proteins / Q000378:metabolism; D006801:Humans; D007223:Infant; D008297:Male; D008663:Metacarpus / Q000000981:diagnostic imaging; D010014:Osteolysis / Q000000981:diagnostic imaging; D010281:Parathyroid Hormone / Q000097:blood; D011547:Pseudohypoparathyroidism / Q000097:blood / Q000000981:diagnostic imaging* / Q000652:urine; D011859:Radiography; D012189:Retrospective Studies; D012871:Skin Diseases / Q000000981:diagnostic imaging