title: Transnasal endoscopic repair of congenital defects of the skull base in children.
abstract: OBJECTIVE
  To examine imaging findings and methods of endoscopic treatment of congenital skull base defects in children.
  
  
  METHODS
  Retrospective study and case series.
  
  
  METHODS
  Academic tertiary care center.
  
  
  METHODS
  Four patients (aged 12 and 14 months and 8 and 13 years) were included from 1995 to 1997. Three presented with a nasal glioma, which was recurrent in 1 case. The fourth patient presented with bacterial meningitis due to a spontaneous cerebrospinal fluid leak. Computed tomography and magnetic resonance imaging were used to locate the defect of the skull base.
  
  
  METHODS
  Transnasal endoscopic resection of the glioma or the meningocele, with immediate repair of the skull base defects using free mucosal flaps and/or pediculized mucosal flaps and/or conchal cartilage together with fibrin glue and nasal packing during a 3-week period.
  
  
  RESULTS
  None of the 4 patients has experienced recurrent cerebrospinal fluid leaks or postoperative meningitis.
  
  
  CONCLUSIONS
  The transnasal endoscopic repair of congenital meningoceles is a reliable technique in select pediatric patients. Computed tomography and magnetic resonance imaging provide information that can be used to help the surgical procedure.
mesh_terms: D000293:Adolescent; D002559:Cerebrospinal Fluid Rhinorrhea / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D004724:Endoscopy; D005910:Glioma / Q000601:surgery*; D006801:Humans; D007223:Infant; D008588:Meningocele / Q000601:surgery*; D009364:Neoplasm Recurrence, Local; D009669:Nose Neoplasms / Q000209:etiology / Q000601:surgery*; D012189:Retrospective Studies; D012886:Skull / Q000002:abnormalities*