[Effect of yishen xiezhou recipe on mesangium cell of chronic renal failure rats].
OBJECTIVE
To observe the effect of Yishen Xiezhuo Recipe (YSXZR) on glomerular mesangium cell (MSC) proliferation.


METHODS
YSXZR was given to healthy and experimental CRF rats by gastrogavage, and the effect of their serum on MSC proliferation was observed.


RESULTS
The serum could obviously inhibit the MSC proliferation. Compared with control rats to which physiological saline was given, the difference was significant (P < 0.01).


CONCLUSIONS
YSXZR could postpone CRF progress.
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D005920:Glomerular Mesangium / Q000166:cytology / Q000187:drug effects; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000188:drug therapy; D008297:Male; D051381:Rats; D017208:Rats, Wistar