title: [Immobilization of the lytic enzyme complex lysoricephine].
abstract: Entrapping of the lysoenzyme complex of lysoricephine in solutions of hydrophilic polymers and its immobilization on dressing materials were performed. Immobilized preparations that retained 80-100% of the lytic activity and stable during storage were obtained. Properties of the immobilized preparations: dependence on pH and temperature, stability in acidic medium, and effect of gamma-radiation were studied. It was shown that coimmobilization with protease C induced a 1.5-1.7-fold increase in the lytic activity of the immobilized preparation compared to the native enzyme complex of lysoricephine.
mesh_terms: D004795:Enzyme Stability; D004800:Enzymes, Immobilized / Q000378:metabolism* / Q000528:radiation effects; D005720:Gamma Rays; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D010447:Peptide Hydrolases / Q000378:metabolism* / Q000528:radiation effects; D011108:Polymers; D013302:Streptomyces / Q000201:enzymology; D013696:Temperature