Submammary granular parakeratosis: an acquired punctate hyperkeratosis of exogenic origin.
Granular parakeratosis is a histologic phenomenon that produces a characteristic clinical picture with multiple brownish and hyperkeratotic papules. In all 6 published cases of localized axillary parakeratosis, excessive use of different topical preparations (cream-type products, deodorants that include roll-on and stick types, antiperspirants, shampoos, bath soaps) was reported by the authors. The exact pathogenic causal relationships have not yet been resolved. In the case reported below, we demonstrate for the first time that the macro- and micromorphological entities can also occur in the submammary region.
D000328:Adult; D001941:Breast Diseases / Q000209:etiology* / Q000473:pathology; D002467:Cell Nucleus / Q000648:ultrastructure; D003879:Dermatologic Agents / Q000009:adverse effects; D004817:Epidermis / Q000473:pathology; D005260:Female; D006801:Humans; D006818:Hyalin / Q000737:chemistry; D015603:Keratinocytes / Q000473:pathology; D007633:Keratins / Q000032:analysis; D007642:Keratosis / Q000209:etiology* / Q000473:pathology; D010241:Parakeratosis / Q000209:etiology* / Q000473:pathology; D017592:Skin Care / Q000009:adverse effects; D007507:Therapeutic Irrigation / Q000009:adverse effects