title: How to determine if an additional 10x safety factor is needed for chemicals: a case study with chlorpyrifos.
mesh_terms: D000328:Adult; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D004390:Chlorpyrifos / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D004781:Environmental Exposure / Q000331:legislation & jurisprudence; D005260:Female; D005506:Food Contamination / Q000331:legislation & jurisprudence; D006801:Humans; D007223:Infant; D007306:Insecticides / Q000633:toxicity*; D011247:Pregnancy; D018570:Risk Assessment / Q000379:methods; D012449:Safety