The morphological features of locally recurrent melanoma and cutaneous metastases of melanoma.
Local recurrence of melanoma at the primary excision site usually implies that the primary excision was incomplete or "inadequate" and that the recurrence was attributable to retained primary melanoma cells or occult melanoma metastases in the adjacent tissue. Pathologists frequently report these tumors in the scar as recurrent or residual melanoma, apparently without considering the possibility that they may be local metastases and manifestations of systemic disease. In this study of 72 cases, we have shown that the morphological features of locally recurrent melanoma, excluding persistent incompletely excised primary melanoma, and cutaneous metastases of melanoma were identical. Because the prevention of local recurrence is the main reason for wide excision of melanoma beyond complete excision of the primary tumor itself, it is essential that pathologists should classify these neoplasms precisely as either persistent incompletely excised primary melanoma or metastatic melanoma.
Yu
L L
LL
Department of Pathology, University of Western Australia, Nedlands.
Heenan
P J
PJ
D003937:Diagnosis, Differential; D006801:Humans; D008545:Melanoma / Q000473:pathology* / Q000556:secondary*; D009362:Neoplasm Metastasis / Q000473:pathology*; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology* / Q000556:secondary*