title: Histochemical localization of hyaluronan and versican in the rat molar dental pulp.
abstract: The distribution of hyaluronan and versican in the dental pulp of the young rat was mapped histochemically. The pattern of staining showed considerable variation between different teeth and different specimens. The most common pattern was a strong reaction for hyaluronan and a weak reaction for versican in the subodontoblastic region, with the reverse deeper in the pulp. This was not an entirely consistent pattern and there was considerable regional variation in the staining intensity for both molecules. The localization of these molecules at similar sites could thus indicate related roles in the connective tissue matrix rather than any chemical bonding between them.
authors.affiliation: 1st Department of Oral Anatomy, School of Dentistry, Tokyo Medical and Dental University, Japan. S.Shibata.oan1@dent.tmd.ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Shibata
authors.forename: S
authors.initials: S
authors.lastname: Kaneko
authors.forename: M
authors.initials: M
authors.lastname: Yanagishita
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashita
mesh_terms: D000818:Animals; D011508:Chondroitin Sulfate Proteoglycans / Q000032:analysis*; D004396:Coloring Agents; D003239:Connective Tissue Cells / Q000166:cytology / Q000648:ultrastructure; D003782:Dental Pulp / Q000166:cytology* / Q000648:ultrastructure; D006651:Histocytochemistry; D006820:Hyaluronic Acid / Q000032:analysis*; D007124:Immunoenzyme Techniques; D037102:Lectins / Q000032:analysis*; D037181:Lectins, C-Type; D008297:Male; D008963:Molar; D009804:Odontoblasts / Q000166:cytology / Q000648:ultrastructure; D011509:Proteoglycans / Q000032:analysis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D053675:Versicans
chemical_list: D011508:Chondroitin Sulfate Proteoglycans; D004396:Coloring Agents; D037102:Lectins; D037181:Lectins, C-Type; D011509:Proteoglycans; C508324:Vcan protein, rat; D053675:Versicans; D006820:Hyaluronic Acid