title: Diversity assessment.
abstract: Several themes have been highlighted recently in both conferences and publications: the availability of product-focused and pharmacophore-based methods for the analysis and design of combinatorial libraries; the power of cell-based methods for molecular similarity, diversity and library design applications; methods for 'rational' diverse subset selection (with applicability to library design); the need for specialized optimization programs for the design of combinatorial libraries that maximize the use of common reagents; and the concept of 'drug-likeness' and its importance in the design of combinatorial libraries.
authors.affiliation: Bristol-Myers Squibb, PO Box 4000, Princeton, NJ 08543, USA. masonj@bms.com
authors.forename: J S
authors.initials: JS
authors.lastname: Mason
authors.forename: M A
authors.initials: MA
authors.lastname: Hermsmeier
mesh_terms: D000465:Algorithms; D002625:Chemistry, Organic / Q000379:methods*; D009930:Organic Chemicals / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D009930:Organic Chemicals