title: [Effective treatment of a large muscle hernia by local botulinum toxin administration].
abstract: A 53-year-old patient developed an impairing muscle hernia when a fascia lata graft was harvested as a substitute for a cruciate ligament of the knee and closure of the defect was not possible. The fascial defect enlarged with time, extending along the whole upper leg. The large muscle protrusion and incarceration in the distal fascial slit was extremely painful during walking and getting up from a chair. Since autologous grafts were disregarded because of the high tissue pressure and alloplastic substitutes seemed problematic, the large hernia was successfully reduced by local muscle denervation with injections of botulinum-A toxin into the protruding vastus lateralis muscle. This procedure achieved relief of pain and enabled the patient to walk without complaints. Side effects were not observed.
authors.affiliation: Klinik für Wiederherstellungschirurgie, Universitätsspitals Zürich.
authors.forename: D
authors.initials: D
authors.lastname: Burg
authors.forename: H
authors.initials: H
authors.lastname: Schnyder
authors.forename: R
authors.initials: R
authors.lastname: Buchmann
authors.forename: V E
authors.initials: VE
authors.lastname: Meyer
mesh_terms: D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D005206:Fascia Lata / Q000637:transplantation; D006547:Hernia / Q000188:drug therapy*; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D009121:Muscle Denervation; D009135:Muscular Diseases / Q000188:drug therapy*; D011183:Postoperative Complications / Q000188:drug therapy; D013848:Thigh
chemical_list: D019274:Botulinum Toxins, Type A