[On the pathogenesis of chronic dust-related bronchitis (according to the status of immune and thrombin-plasmin systems].
As a result of the performed investigations there was revealed the injury of T-link of the systemic immunity, as well, as the reduction of the immunoglobulin A. And in the sick with chronic dust bronchitis the state of local immunity was characterized by the increase of the per cent content of neutrophilic granulocytes in the bronchoalveolar washout, and also by the reduction of adgesive and absorptive ability of the alveolar macrophages at the background of significant activation of the oxygendependent metabolism. The investigation of coagulant blood system revealed the predomination of thrombinogenesis over the processes of fibrinolysis.
Kurilo
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SN
D000328:Adult; D000917:Antibody Formation / Q000276:immunology*; D001991:Bronchitis / Q000201:enzymology / Q000209:etiology / Q000276:immunology; D002908:Chronic Disease; D004391:Dust / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D009784:Occupational Diseases / Q000209:etiology* / Q000276:immunology*; D012697:Serine Endopeptidases / Q000378:metabolism*; D013917:Thrombin / Q000378:metabolism*
D004391:Dust; D012697:Serine Endopeptidases; D013917:Thrombin