Cutaneous extravascular necrotizing granuloma (Churg Strauss granuloma).
Churg Strauss granuloma (cutaneous extravascular necrotizing granuloma) is a distinct entity which is associated with systemic immunoreactive or autoimmune diseases in a majority of cases. Typically, Churg Strauss granuloma presents as symmetrical papules or nodules on the extremities. There are two histological patterns: the classic pattern reveals palisading granuloma with central degenerated collagen, interspersed polymorphonuclear leukocytes, and leukocytoclastic debris; the focal basophilic necrosis pattern does not show palisading granuloma. We report two cases of Churg Strauss granuloma with different histopathological patterns.
Lee
M W
MW
Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
Jang
K A
KA
Lim
Y S
YS
Choi
J H
JH
Sung
K J
KJ
Moon
K C
KC
Koh
J K
JK
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000974:Antibodies, Antinuclear / Q000032:analysis; D001706:Biopsy; D001799:Blood Sedimentation; D015267:Churg-Strauss Syndrome / Q000097:blood / Q000188:drug therapy / Q000473:pathology*; D003094:Collagen / Q000648:ultrastructure; D003622:Dapsone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020556:Neutrophil Infiltration; D011239:Prednisolone / Q000627:therapeutic use; D012217:Rheumatoid Factor / Q000032:analysis; D012867:Skin / Q000473:pathology*
D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000974:Antibodies, Antinuclear; D003622:Dapsone; D003094:Collagen; D012217:Rheumatoid Factor; D011239:Prednisolone