[Chronic acquired hepatocerebral degeneration: the role of manganese and treatment by endovascular occlusion of a porto-systemic shunt].
This case report describes a 74 year-old woman with cirrhosis who developed choreo-athetotic movements associated with elevated whole blood manganese and symmetric hyperintense pallidum on T1-weighted magnetic resonance imaging. The diagnosis was chronic acquired hepatocerebral degeneration. The endovascular occlusion of portal-systemic shunts was temporarily effective.
Condat
B
B
Service des Maladies du Foie et de l'Appareil Digestif, Centre Hospitalier Universitaire Bicêtre, Kremlin-Bicêtre.
Dusoleil
A
A
Bernardeau
M
M
Roche
A
A
Pelletier
G
G
Buffet
C
C
D000368:Aged; D002819:Chorea / Q000097:blood / Q000209:etiology / Q000628:therapy; D002908:Chronic Disease; D004621:Embolization, Therapeutic; D005260:Female; D006527:Hepatolenticular Degeneration / Q000097:blood / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008274:Magnesium / Q000097:blood*; D011170:Portasystemic Shunt, Surgical / Q000009:adverse effects*
D008274:Magnesium