title: BACTOX, a rapid bioassay that uses protozoa to assess the toxicity of bacteria.
abstract: A new type of toxicity test based on the protozoan Tetrahymena pyriformis has been developed to assess the overall toxicity of bacterial strains given as prey. This simple and rapid test is able to detect toxicant-producing bacteria, which may present a biohazard. It can also be used for the risk assessment of microbes designed for deliberate release.
authors.affiliation: Novartis Pharma AG, CH-4002 Basel, Switzerland.
authors.forename: W
authors.initials: W
authors.lastname: Schlimme
authors.forename: M
authors.initials: M
authors.lastname: Marchiani
authors.forename: K
authors.initials: K
authors.lastname: Hanselmann
authors.forename: B
authors.initials: B
authors.lastname: Jenni
mesh_terms: D000818:Animals; D001419:Bacteria / Q000254:growth & development* / Q000378:metabolism; D001681:Biological Assay / Q000379:methods*; D015203:Reproducibility of Results; D013769:Tetrahymena pyriformis / Q000254:growth & development*; D018675:Toxicity Tests / Q000379:methods*