[Molecular mechanisms of major radiobiological sequels of the effect of ionizing radiation on mammals].
The modern knowledge about the molecular bases of reproductive cell death, apoptosis, necrosis and disturbance of the cell reproduction, the main causes of radiation sickness and radiation death of mammals and men was considered. It was marked, that these deterministic effects of ionizing radiation as the stochastic effects (mutagenesis and carcinogenesis) have an common molecular basis that most full opened up by study of apoptosis and including in complex genetical and biochemical phenomena of DNA repair.
Mazurik
V K
VK
State Research Centre of Russia, Institute of Biophysics, Moscow.
Mikhaĭlov
V F
VF
D000818:Animals; D004260:DNA Repair; D006801:Humans; D016296:Mutagenesis; D009381:Neoplasms, Radiation-Induced / Q000209:etiology; D011832:Radiation Injuries / Q000209:etiology*; D011836:Radiation Tolerance; D013269:Stochastic Processes