[Detection of respiratory syncytial virus using immunohistochemistry. Report of 53 cases of sudden infant death].
We analyzed 53 cases of sudden infant death to detect immunohistochemical expression of respiratory syncytial virus on pulmonary sections. The virus was identified in 7 cases. The immunohistochemical staining was intracytoplasmic and mainly observed in bronchioles. Among these 7 cases, 6 showed severe pulmonary lesions which were assumed to be accountable for decrease. The inflammatory lesions related to respiratory syncytial virus were diffuse, located with the same intensity to either bronchi, bronchioles, alveoles and upper respiratory tract. The immunohistochemical staining was markedly heterogeneous, requiring numerous pulmonary samples.
Siani
V
V
Service d'anatomie pathologique, CHG de Tarbes.
Netter
J C
JC
Gorguet
B
B
Carles
D
D
Pellegrin de Villeneuve
M
M
D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D007231:Infant, Newborn; D008171:Lung Diseases / Q000821:virology; D008297:Male; D012136:Respiratory Syncytial Viruses / Q000302:isolation & purification*; D013398:Sudden Infant Death / Q000209:etiology*