title: Paroxysmal laryngospasm after laryngeal nerve injury.
abstract: OBJECTIVE
  Describe a clinical syndrome of laryngeal hypersensitivity following laryngeal nerve injury.
  
  
  METHODS
  Retrospective review of six patients with laryngeal paralysis sustained during neck surgery who presented with paroxysms of coughing and stridor, progressing to brief episodes of complete airway occlusion.
  
  
  METHODS
  Chart review.
  
  
  RESULTS
  Superior laryngeal nerve blockade temporarily improved symptoms in four of five patients. Botulinum toxin relieved spasm in two of three patients and reduced symptoms in the third. Symptoms gradually diminished or resolved in four patients from 1 to 2.5 years later. One patient underwent arytenoidectomy and one patient has a tracheostomy.
  
  
  CONCLUSIONS
  Patients with laryngeal injury may present with stridor and acute airway obstruction secondary to paroxysmal laryngospasm. The authors have found that superior laryngeal nerve blockade or botulinum toxin may be effective in temporary relief of symptoms.
authors.affiliation: University of Tennessee School of Medicine, Department of Otolaryngology/Head and Neck Surgery, Memphis 38163, USA.
authors.forename: M K
authors.initials: MK
authors.lastname: Wani
authors.forename: G E
authors.initials: GE
authors.lastname: Woodson
mesh_terms: D000328:Adult; D018726:Anti-Dyskinesia Agents / Q000627:therapeutic use; D001905:Botulinum Toxins / Q000627:therapeutic use; D005260:Female; D006801:Humans; D061224:Laryngeal Nerve Injuries; D007826:Laryngismus / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000150:complications* / Q000188:drug therapy
chemical_list: D018726:Anti-Dyskinesia Agents; D001905:Botulinum Toxins