The protective role of 11 beta-hydroxysteroid dehydrogenase/carbonyl reductase against tobacco-smoke related lung cancer.
Maser
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Department of Pharmacology and Toxicology, Philipps-University, Marburg, Germany.
D042842:11-beta-Hydroxysteroid Dehydrogenases; D000429:Alcohol Oxidoreductases / Q000096:biosynthesis / Q000302:isolation & purification / Q000502:physiology; D000818:Animals; D005938:Glucocorticoids / Q000378:metabolism; D006034:Glycyrrhetinic Acid / Q000378:metabolism; D006913:Hydroxysteroid Dehydrogenases / Q000096:biosynthesis / Q000302:isolation & purification / Q000502:physiology*; D007700:Kinetics; D008168:Lung / Q000201:enzymology; D008175:Lung Neoplasms / Q000201:enzymology* / Q000209:etiology; D051379:Mice; D009602:Nitrosamines / Q000378:metabolism; D010084:Oxidation-Reduction; D051381:Rats; D012907:Smoking / Q000009:adverse effects*
D005938:Glucocorticoids; D009602:Nitrosamines; C016583:4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; D000429:Alcohol Oxidoreductases; D006913:Hydroxysteroid Dehydrogenases; D042842:11-beta-Hydroxysteroid Dehydrogenases; D006034:Glycyrrhetinic Acid