Aspergillus fumigatus endophthalmitis in a patient with acute myeloid leukaemia.
A 55-year-old patient developed progressive loss of vision in one eye following induction chemotherapy for acute myeloid leukaemia (AML). Aspergillus fumigatus was cultured from vitreal aspirates. The patient was treated with intravenous and intravitreal amphotericin B but suffered complete loss of vision in her right eye. We believe this is the first report of culture-proven Aspergillus fumigatus endophthalmitis in a patient treated for a haematological malignancy.
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Department of Haematology, Huddersfield Royal Infirmary, Lindley, UK.
Hutchinson
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Martin
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Carter
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D000208:Acute Disease; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D001228:Aspergillosis / Q000139:chemically induced*; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D009877:Endophthalmitis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000188:drug therapy*; D008875:Middle Aged