title: Alternative methods for reduction of blood loss during elective orthognathic surgery.
abstract: Bimaxillary orthognathic surgery and genioplasty are frequently performed to correct dentoskeletal anomalies in otherwise healthy young patients. Until 1990 homologous blood transfusions were routinely necessary for these procedures. The present study describes a protocol of blood-saving measures that was adopted and tested on a continuous sample of 127 patients treated between 1994 and 1997. The protocol comprises acute normovolemic hemodilution, controlled moderate hypotension, positioning the surgical field above the heart level, cell saving, intraoperative homeostasis, preoperative autologous blood donation, administration of recombinant erythropoietin, and acceptance of a low hematocrit perioperatively. This study shows that homologous blood transfusions may be avoided intraoperatively by following the protocol described.
authors.affiliation: Department of Craniomaxillofacial Surgery, University Hospital Zurich, Switzerland. roman.rohling@ifa.usz.ch
authors.forename: R G
authors.initials: RG
authors.lastname: Rohling
authors.forename: A P
authors.initials: AP
authors.lastname: Zimmermann
authors.forename: P
authors.initials: P
authors.lastname: Biro
authors.forename: P E
authors.initials: PE
authors.lastname: Haers
authors.forename: H F
authors.initials: HF
authors.lastname: Sailer
mesh_terms: D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001804:Blood Transfusion, Autologous; D004921:Erythropoietin / Q000627:therapeutic use; D005069:Evaluation Studies as Topic; D006438:Hemodilution / Q000379:methods; D006706:Homeostasis; D006801:Humans; D007023:Hypotension, Controlled; D019647:Oral Surgical Procedures / Q000009:adverse effects*; D056948:Orthognathic Surgical Procedures; D011300:Preoperative Care; D011446:Prospective Studies; D011994:Recombinant Proteins
chemical_list: D011994:Recombinant Proteins; D004921:Erythropoietin