title: 4-[[2-(1-Methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A): a novel cognitive enhancer with selectivity for neuronal nicotinic acetylcholine receptors.
authors.affiliation: SIBIA Neurosciences Inc., 505 Coast Boulevard South, La Jolla, California 92037, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Vernier
authors.forename: H
authors.initials: H
authors.lastname: El-Abdellaoui
authors.forename: H
authors.initials: H
authors.lastname: Holsenback
authors.forename: N D
authors.initials: ND
authors.lastname: Cosford
authors.forename: L
authors.initials: L
authors.lastname: Bleicher
authors.forename: G
authors.initials: G
authors.lastname: Barker
authors.forename: B
authors.initials: B
authors.lastname: Bontempi
authors.forename: L
authors.initials: L
authors.lastname: Chavez-Noriega
authors.forename: F
authors.initials: F
authors.lastname: Menzaghi
authors.forename: T S
authors.initials: TS
authors.lastname: Rao
authors.forename: R
authors.initials: R
authors.lastname: Reid
authors.forename: A I
authors.initials: AI
authors.lastname: Sacaan
authors.forename: C
authors.initials: C
authors.lastname: Suto
authors.forename: M
authors.initials: M
authors.lastname: Washburn
authors.forename: G K
authors.initials: GK
authors.lastname: Lloyd
authors.forename: I A
authors.initials: IA
authors.lastname: McDonald
mesh_terms: D000818:Animals; D001667:Binding, Competitive; D002460:Cell Line; D002540:Cerebral Cortex / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D009474:Neurons / Q000378:metabolism*; D018722:Nicotinic Agonists / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D018697:Nootropic Agents / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D009865:Oocytes; D018408:Patch-Clamp Techniques; D010636:Phenols / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley; D011978:Receptors, Nicotinic / Q000378:metabolism*; D014162:Transfection; D014981:Xenopus
chemical_list: C119207:4-((2-(1-methyl-2-pyrrolidinyl)ethyl)thio)phenol hydrochloride; D018722:Nicotinic Agonists; D018697:Nootropic Agents; D010636:Phenols; D011759:Pyrrolidines; D011978:Receptors, Nicotinic