Plans, designs, and analyses for clinical trials of anti-cocaine medications: where we are today. NIDA/VA/SU Working Group on Design and Analysis.
Increased interest in addiction psychopharmacology has raised unique methodologic issues in the design, conduct, and analysis of outcomes in clinical trials of therapeutic agents for drug dependence. This article summarizes issues raised at a meeting in Palo Alto, California, on November 4, 1996, that was sponsored by the Medication Development Division of the National Institute on Drug Abuse and the Department of Veterans Affairs Cooperative Studies Program to discuss the methodologic issues in clinical trials of cocaine pharmacotherapy.
Lavori
P W
PW
VA Cooperative Studies Program, Palo Alto VAHCS, California 94304, USA. lavori@odd.stanford.edu
Bloch
D A
DA
Bridge
P T
PT
Leiderman
D B
DB
LoCastro
J S
JS
Somoza
E
E
D001521:Behavior Therapy; D002986:Clinical Trials as Topic; D019970:Cocaine-Related Disorders / Q000188:drug therapy*; D006801:Humans; D010043:Outcome and Process Assessment, Health Care; D010349:Patient Compliance; D012107:Research Design