title: Multiple renal aspergillus abscesses in an AIDS patient: contrast-enhanced helical CT and MRI findings.
abstract: Renal insufficiency or allergic reactions for X-ray contrast agents are frequent limitations in immunocompromised hosts such as neutropenic or AIDS patients. Due to a better tolerance of contrast agents in MRI, this technique is well suited for investigation of parenchymal organs. We demonstrate an allergic AIDS patient who presented with fever and flank pain. At sonography, anechoic renal lesions were supposed to be non-complicated cysts; however, on T2-weighted MRI, the center was of high signal. Dynamic contrast-enhanced MRI of the kidneys demonstrated an enhancing rim with ill-defined margins. The lesions were supposed to be multiple bilateral abscesses. Due to the multiple dynamic contrast series, a delayed enhancement of renal parenchyma was detectable adjacent to the lesion. This was suggested as accompanying local pyelonephritis and an infectious etiology became more reliable. Aspergillus fumigatus was identified by CT-guided biopsy as the underlying microorganism. The MR appearance of this manifestation has not been described previously.
authors.affiliation: Department of Radiology, Johannes Gutenberg University, Mainz, Germany. heussel@mail.uni-mainz.de
authors.forename: C P
authors.initials: CP
authors.lastname: Heussel
authors.forename: H U
authors.initials: HU
authors.lastname: Kauczor
authors.forename: G
authors.initials: G
authors.lastname: Heussel
authors.forename: M
authors.initials: M
authors.lastname: Thelen
authors.forename: B
authors.initials: B
authors.lastname: Jahn
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000000981:diagnostic imaging* / Q000382:microbiology; D000038:Abscess / Q000000981:diagnostic imaging* / Q000382:microbiology; D000328:Adult; D001228:Aspergillosis / Q000000981:diagnostic imaging* / Q000382:microbiology; D001232:Aspergillus fumigatus / Q000302:isolation & purification; D001706:Biopsy; D003287:Contrast Media; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D019786:Gadolinium DTPA; D006801:Humans; D007472:Iohexol / Q000031:analogs & derivatives; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011704:Pyelonephritis / Q000175:diagnosis* / Q000382:microbiology; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007472:Iohexol; C038192:iopromide; D019786:Gadolinium DTPA