Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting enzyme, instilled intra-arterially in patients with advanced-stage pancreatic carcinoma: a phase I/II study.
Löhr
M
M
Department of Medicine, University of Rostock, Germany. loehr@med.uni-rostock.de
Bago
Z T
ZT
Bergmeister
H
H
Ceijna
M
M
Freund
M
M
Gelbmann
W
W
Günzburg
W H
WH
Jesnowski
R
R
Hain
J
J
Hauenstein
K
K
Henninger
W
W
Hoffmeyer
A
A
Karle
P
P
Kröger
J C
JC
Kundt
G
G
Liebe
S
S
Losert
U
U
Müller
P
P
Probst
A
A
Püschel
K
K
Renner
M
M
Renz
R
R
Saller
R
R
Salmons
B
B
Walter
I
I
D000328:Adult; D000368:Aged; D002460:Cell Line; D019362:Cytochrome P-450 CYP2B1 / Q000008:administration & dosage* / Q000235:genetics*; D004339:Drug Compounding; D005260:Female; D015316:Genetic Therapy; D005822:Genetic Vectors; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000628:therapy*; D014162:Transfection
D019362:Cytochrome P-450 CYP2B1; D007069:Ifosfamide