title: Regression of a large solid papillary craniopharyngioma following fractionated external radiotherapy.
abstract: We present a patient harboring a large squamous papillary craniopharyngioma. The diagnosis was confirmed by a stereotactic biopsy. Because of vegetative symptoms indicating hypothalamic derangement, we were reluctant to perform surgical resection. Following fractionated megavoltage radiotherapy, MR imaging and CT demonstrated complete regression of the craniopharyngioma and the patient recovered from endocrine deficiency, chiasmal syndrome and vegetative hypothalamic symptoms.
authors.affiliation: Department of Neurosurgery, University of Erlangen-Nürnberg, Erlangen, Germany. honegger@nz11.ukl.uni-freiburg.de
authors.forename: J
authors.initials: J
authors.lastname: Honegger
authors.forename: G G
authors.initials: GG
authors.lastname: Grabenbauer
authors.forename: W
authors.initials: W
authors.lastname: Paulus
authors.forename: R
authors.initials: R
authors.lastname: Fahlbusch
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D002552:Cerebral Ventricles; D003397:Craniopharyngioma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D019583:Dose Fractionation, Radiation; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011882:Radiotherapy, High-Energy; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome