[The genomic characterization of the Cuban strain with a light cytopathic effect].
The genomic characterization of the strain of light cytopathic effect by nucleotide sequence is presented. It was possible to sequence 90% of the strain of light cytopathic effect. A close relationship with Coxsackie A9 was observed. The greatest mutations occurred in the region of the genome that codifies for the structural proteins. Therefore, it may be considered as a variant of Coxsackie A9 never reported before.
Alvarez Vera
M
M
Instituto de Medicina Tropical Pedro Kourí, Ciudad de La Habana, Cuba.
Sarmiento Pérez
L
L
Guzmán Tirado
M G
MG
Beck
M
M
Shi
Q
Q
Handy
J
J
Más Lago
P
P
D000818:Animals; D001483:Base Sequence; D002522:Chlorocebus aethiops; D003462:Cuba; D003588:Cytopathogenic Effect, Viral; D004770:Enterovirus / Q000235:genetics* / Q000472:pathogenicity; D016679:Genome, Viral; D009154:Mutation; D016133:Polymerase Chain Reaction; D017385:Sequence Homology; D014709:Vero Cells; D014776:Virus Cultivation