title: Spiradenocarcinoma: morphological and immunohistochemical features.
abstract: Malignant transformation of spiradenoma is a very rare event and its biologic features have not been fully described. Clinically, these tumours are characterized by the rapid enlargement of a long-standing cutaneous nodule. Microscopic examination discloses the presence of the two components, benign and malignant, whose morphological distinction is not always easy. We report the occurrence of a spiradenocarcinoma within a pre-existing spiradenoma of the cheek in a 48 year old man and review the previously reported cases especially on the basis of their morphological and immunohistochemical characteristics.
authors.affiliation: Department of Anatomical Pathology, University of Udine, Udine, 33100 Italy.
authors.initials: M
authors.lastname: Delendi
authors.initials: F
authors.lastname: Puglisi
authors.lastname: Della Mea V
authors.initials: C
authors.lastname: Riberti
authors.initials: M
authors.lastname: Osti
authors.initials: PC
authors.lastname: Parodi