title: Motor perseverative behavior on a line cancellation task.
abstract: OBJECTIVE
  To study the behavioral and neuroanatomic characteristics of perseverative behavior encountered on a target cancellation task in patients with neglect.
  
  
  METHODS
  Motor perseverative behavior during line cancellation task was evaluated retrospectively in 60 patients with left hemispatial neglect from right hemispheric stroke.
  
  
  RESULTS
  More than 30% of the patients (21 of 60) showed perseveration, manifested as either repetitive cancellation of the same target (18/21) or cancelling extra lines created by the patients themselves (3/21). Neglect severity correlated positively with the frequency of perseverative errors. Perseveration was most prominent in the rightmost portion of the array. Anterior lesions or massive lesions involving anterior and posterior regions were more likely to be associated with motor perseveration than were lesions restricted to posterior areas.
  
  
  CONCLUSIONS
  Although the mechanism of motor perseveration remains to be elucidated, our findings suggest that the combination of aberrant approach behaviors associated with frontal lobe injury and an attentional or intentional bias toward the rightsided targets might explain the behavior.
authors.affiliation: Department of Neurology, College of Medicine, Sungkyunkwan University, Samsung Medical Center, Seoul, Korea.
authors.forename: D L
authors.initials: DL
authors.lastname: Na
authors.forename: J C
authors.initials: JC
authors.lastname: Adair
authors.forename: Y
authors.initials: Y
authors.lastname: Kang
authors.forename: C S
authors.initials: CS
authors.lastname: Chung
authors.forename: K H
authors.initials: KH
authors.lastname: Lee
authors.forename: K M
authors.initials: KM
authors.lastname: Heilman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001519:Behavior / Q000502:physiology*; D002561:Cerebrovascular Disorders / Q000503:physiopathology* / Q000523:psychology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011597:Psychomotor Performance / Q000502:physiology*