title: Eosinophilic pustular folliculitis in infancy: report of two new cases.
abstract: Eosinophilic pustular folliculitis (EPF) is a cutaneous inflammatory follicular disorder of unknown etiology. The diagnosis is made on the basis of clinical and histopathologic features. We describe two patients who had recurrent episodes of pruritic follicular papular and pustular lesions on the face, extremities, and trunk. The eruptions lasted for 1 month with intermittent remissions. Laboratory tests disclosed no infectious or parasitic etiology in patient 2. In patient 1 we isolated methicillin-resistant Staphylococcus aureus in a blood culture. He had sepsis with lung and liver involvement. EPF is a self-limited dermatosis. On occasion, skin lesions may become superinfected, resulting in localized pyoderma or rarely systemic infection (sepsis). Histologically both of our patients showed a moderate mixed inflammatory infiltrate with numerous eosinophils centered around hair follicles. Their lesions responded well to topical corticosteroids.
authors.affiliation: Department of Pediatric Dermatology, Ramos Mejía Hospital, Buenos Aires, Argentina.
authors.forename: M
authors.initials: M
authors.lastname: Larralde
authors.forename: S
authors.initials: S
authors.lastname: Morales
authors.forename: A
authors.initials: A
authors.lastname: Santos Muñoz
authors.forename: F
authors.initials: F
authors.lastname: Lamas
authors.forename: R
authors.initials: R
authors.lastname: Schroh
authors.forename: C
authors.initials: C
authors.lastname: Corbella
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D004802:Eosinophilia / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D004804:Eosinophils / Q000473:pathology; D005499:Folliculitis / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D000068656:Mometasone Furoate; D011244:Pregnadienediols / Q000627:therapeutic use; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D013203:Staphylococcal Infections / Q000150:complications
chemical_list: D000893:Anti-Inflammatory Agents; D011244:Pregnadienediols; D000068656:Mometasone Furoate