Organochlorines in breast milk from two cities in Ukraine.
Reports of environmental problems in the former Soviet Union, including excess use of pesticides, have led to concerns about high levels of contamination in humans, but little information is available to assess whether these concerns are warranted. Samples of breast milk from 197 women from two cities in Ukraine were analyzed for p,p'-DDT, p,p'-DDE, endrin, dieldrin, heptachlor epoxide, trans-nonachlor, oxychlordane, hexachlorobenzene, ss-hexachlorocyclohexane (HCH), and 18 polychlorinated biphenyl congeners, and results were compared to previous reports from Europe. The median ss-HCH concentration was 731 ng/g milk fat, which is higher than other reports from Europe but lower than reports from other parts of the world. The median DDE concentration was 2,457 ng/g milk fat, which is higher than most but not all other reports from Europe. Concentrations of other chemicals were comparable to or lower than other reports from Europe. Concentrations from the city of Kyiv were generally lower than those from Dniprodzerzhinsk, but the magnitudes of these differences were modest.
Gladen
B C
BC
National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA. gladen@niehs.nih.gov
Monaghan
S C
SC
Lukyanova
E M
EM
Hulchiy
O P
OP
Shkyryak-Nyzhnyk
Z A
ZA
Sericano
J L
JL
Little
R E
RE
D000328:Adult; D000375:Aging / Q000378:metabolism; D005223:Fats / Q000032:analysis; D005260:Female; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D007306:Insecticides / Q000032:analysis; D008895:Milk, Human / Q000737:chemistry*; D011078:Polychlorinated Biphenyls / Q000032:analysis; D014455:Ukraine / Q000453:epidemiology; D014505:Urban Population
D005223:Fats; D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D011078:Polychlorinated Biphenyls