title: Inspiratory flow-volume curve in snoring patients with and without obstructive sleep apnea.
abstract: We analyzed the flow-volume curves of 50 patients with complaints of snoring and daytime sleepiness in treatment at the Pneumology Unit of the University Hospital of Brasília. The total group was divided into snorers without obstructive sleep apnea (OSA) (N = 19) and snorers with OSA (N = 31); the patients with OSA were subdivided into two groups according to the apnea/hypopnea index (AHI): AHI < 20/h (N = 14) and AHI > 20/h (N = 17). The control group (N = 10) consisted of nonsmoking subjects without complaints of snoring, daytime sleepiness or pulmonary diseases. The population studied (control and patients) consisted of males of similar age, height and body mass index (BMI); spirometric data were also similar in the four groups. There was no significative difference in the ratio of forced expiratory and inspiratory flows (FEF50%/FIF50%) in any group: control. 0.89; snorers, 1.11; snorers with OSA (AHI < 20/h), 1.42, and snorers with OSA (AHI > 20/h), 1.64. The FIF at 50% of vital capacity (FIF50%) of snoring patients with or without OSA was lower than the FIF50% of the control group (P < 0.05): snorers 4.30 l/s; snorers with OSA (AHI < 20/h) 3.69 l/s; snorers with OSA (AHI > 20/h) 3.17 l/s and control group 5.48 l/s. The FIF50% of patients with severe OSA (AHI > 20/h) was lower than the FIF50% of snorers without OSA (P < 0.05): 3.17 l/s and 4.30 l/s, respectively. We conclude that 1) the FEF50%/FIF50% ratio is not useful for predicting OSA, and 2) FIF50% is decreased in snoring patients with and without OSA, suggesting that these patients have increased upper airway resistance (UAR).
authors.affiliation: Departamento de Clínica Médica, Faculdade de Ciências da Saúde, Universidade de Brasília, DF, Brasil.
authors.forename: V M
authors.initials: VM
authors.lastname: Amado
authors.forename: A C
authors.initials: AC
authors.lastname: Costa
authors.forename: M
authors.initials: M
authors.lastname: Guiot
authors.forename: C A
authors.initials: CA
authors.lastname: Viegas
authors.forename: P
authors.initials: P
authors.lastname: Tavares
mesh_terms: D006801:Humans; D007320:Inspiratory Capacity; D008297:Male; D008875:Middle Aged; D012123:Pulmonary Ventilation; D012129:Respiratory Function Tests; D012891:Sleep Apnea Syndromes / Q000503:physiopathology*; D012913:Snoring / Q000503:physiopathology*; D014797:Vital Capacity