Solitary fibrous tumor of the pleura: a cytogenetic study.
A solitary fibrous tumor of the pleura was studied. Its karyotype was 46,XY,t(6;17) (p11.2;q23),ins(9;12)(q22;q15q24.1),inv(16)(p13.1q24). The rearrangement of 12q13-15 was also described in a subset of hemangiopericytomas of soft tissue and meninges. Because both types of tumors are morphologically and immunophenotypically quite similar, and because some of them share rearrangement of 12q13-15, the possibility of their histogenetical relatedness should be considered.
Donner
L R
LR
Department of Pathology, Scott & White Clinic, Temple, TX 76508, USA.
Silva
M T
MT
Dobin
S M
SM
D000368:Aged; D018952:Antigens, CD34 / Q000378:metabolism; D002869:Chromosome Aberrations; D002881:Chromosomes, Human, Pair 12; D002886:Chromosomes, Human, Pair 17; D002896:Chromosomes, Human, Pair 6; D003094:Collagen / Q000378:metabolism; D005350:Fibroma / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D015321:Gene Rearrangement; D006801:Humans; D008297:Male; D010997:Pleural Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D014178:Translocation, Genetic; D014746:Vimentin / Q000378:metabolism
D018952:Antigens, CD34; D014746:Vimentin; D003094:Collagen