title: Inclusion body myositis long after dermatomyositis: a report of two cases.
abstract: Dermatomyositis, polymyositis, and inclusion body myositis are rare illnesses which appear to be distinct in clinical and pathologic features, pathogenesis, natural history, and response to therapy. We report two patients who first developed dermatomyositis, and then, after a disease-free interval of many years, developed inclusion body myositis. This may have useful therapeutic implications for patients with dermatomyositis whose illness bocomes refractory to treatment.
authors.affiliation: Arthritis and Rheumatism Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: A L
authors.initials: AL
authors.lastname: McCoy
authors.forename: M R
authors.initials: MR
authors.lastname: Bubb
authors.forename: P H
authors.initials: PH
authors.lastname: Plotz
authors.forename: J C
authors.initials: JC
authors.lastname: Davis
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use; D003402:Creatine Kinase / Q000097:blood; D003882:Dermatomyositis / Q000150:complications* / Q000188:drug therapy / Q000201:enzymology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology; D018979:Myositis, Inclusion Body / Q000150:complications* / Q000188:drug therapy / Q000201:enzymology / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D011239:Prednisolone; D003402:Creatine Kinase; D001379:Azathioprine