title: Visual attention deficits in Alzheimer's disease: simple versus conjoined feature search.
abstract: The authors investigated selective attention in patients with Alzheimer's disease (AD), using a well-known visual search procedure. In simple feature search, the deficit observed in AD patients represented a baseline shift in the median hit reaction time (RT). On the conjoined feature search task, the median hit RT for AD patients increased disproportionately with increasing array size, indicating an additional cognitive impairment on this task. Of particular importance, the cognitive deficit observed in conjunction search was more profound than that predicted on the basis of previous reports of global cognitive slowing in AD. There was some evidence that the performance of AD patients improved more than the performance of controls over the duration of the experimental test session. Patients also had more difficulty in detecting targets on the right side of hemispace and in more peripheral locations.
authors.affiliation: Rotman Research Institute of Baycrest Centre for Geriatric Care, University of Toronto, North York, Ontario, Canada. foster@psy.man.ac.uk
authors.forename: J K
authors.initials: JK
authors.lastname: Foster
authors.forename: M
authors.initials: M
authors.lastname: Behrmann
authors.forename: D T
authors.initials: DT
authors.lastname: Stuss
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000503:physiopathology*; D000704:Analysis of Variance; D001288:Attention / Q000145:classification / Q000502:physiology*; D003072:Cognition Disorders / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual; D011930:Reaction Time / Q000502:physiology*; D014794:Visual Fields / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*