Positive antineutrophil cytoplasmic antibodies-associated vasculitis presenting with hemoptysis and a mediastinal mass.
A patient with end-stage renal failure, due to IgA nephropathy, was found to have a mediastinal mass. Biopsy specimen of the mass showed a necrotizing vasculitis. Antineutrophil antibodies to myeloperoxidase were strongly positive. To our knowledge, no case of a mediastinal mass due vasculitis has been reported in the literature, and our observation should lead to broadening of the spectrum of clinical manifestations of vasculitis.
Fidder
H H
HH
Department of Medicine, Chaim Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel-Hashomer, Israel. gastro@netvision.net.il
Apter
S
S
Langevitz
P
P
Aviel-Ronen
S
S
Bank
I
I
Livneh
A
A
D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis*; D005922:Glomerulonephritis, IGA / Q000150:complications; D006469:Hemoptysis / Q000209:etiology*; D006801:Humans; D008297:Male; D008477:Mediastinal Diseases / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D009336:Necrosis; D014657:Vasculitis / Q000150:complications* / Q000175:diagnosis / Q000276:immunology
D019268:Antibodies, Antineutrophil Cytoplasmic