title: Biochemical and molecular tools for the production of useful terpene products from pepper (Capsicum annuum).
abstract: Among other natural products such as colorants and flavorants, natural fungicides like the pepper phytoalexin capsidiol, and the related biochemical pathways, may be used for practical approaches. Key enzymes such as 3-hydroxy-3-methylglutaryl Coenzyme A: reductase, the farnesyl pyrophosphate synthase and and farnesyl pyrophosphate cyclases are known and some related genes have been isolated. However, specific enzymes for important and final modifications as methylation and others, are still to be studied. Construction of chimeric enzymes allowed already the synthesis of different products and the possibilities of designing new enzymes by gene manipulation to produce unknown and useful chemicals are open.
authors.affiliation: Genetic Engineering Department, CINVESTAV-IPN/Irapuato Unit, Irapuato, Gto., México.
authors.forename: E
authors.initials: E
authors.lastname: Lozoya-Gloria
mesh_terms: D000383:Agriculture / Q000379:methods*; D019883:Alkyl and Aryl Transferases / Q000378:metabolism; D002212:Capsicum / Q000378:metabolism*; D019755:Carbon-Carbon Lyases / Q000378:metabolism; D051228:Geranyltranstransferase; D006903:Hydroxymethylglutaryl CoA Reductases / Q000378:metabolism; D030821:Plants, Genetically Modified; D010946:Plants, Medicinal; D012717:Sesquiterpenes / Q000378:metabolism; D013729:Terpenes / Q000378:metabolism*
chemical_list: D012717:Sesquiterpenes; D013729:Terpenes; D006903:Hydroxymethylglutaryl CoA Reductases; D019883:Alkyl and Aryl Transferases; D051228:Geranyltranstransferase; D019755:Carbon-Carbon Lyases; C051130:trichodiene synthetase