Electron microscopic observation on the parathyroid gland of the cardiomyopathic hamster (UM-X7.1 Syrian hamster).
The ultrastructure of the parathyroid gland (PTG) of the UM-X7.1 cardiomyopathic hamster (the UM-X7.1) was qualitatively and quantitatively compared with that of the normal hamster. In the UM-X7.1, the Golgi apparatus and rER were well developed compared with those of the control hamster. Morphometric analysis revealed that the mean values of the Golgi apparatus, rER and large vacuolar bodies were significantly greater in the UM-X7.1 than in the normal hamster and the mean value of lipid droplets was significantly less in the UM-X7.1 than in the normal hamster. Ultrastructurally, we consider that in the UM-X7.1, the synthesis and release of the parathyroid hormone may be activated by an excessive amount of circulating catecholamine, and the functional activity of the PTG may be higher than that in the normal hamster.
Utsumi
M
M
Department of Anatomy, School of Dentistry, Aichi-Gakuin University, Nagoya, Japan. kosmo@fs.dpc.aichi-gakuin.ac.jp
Moriguchi
K
K
Takahashi
H
H
Kinoshita
C
C
Togari
A
A
Mizutani
M
M
Ohno
N
N
D000818:Animals; D002118:Calcium / Q000097:blood; D002311:Cardiomyopathy, Dilated / Q000473:pathology*; D006224:Cricetinae; D004195:Disease Models, Animal; D018870:Endoplasmic Reticulum, Rough / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D008297:Male; D008647:Mesocricetus; D008854:Microscopy, Electron; D015388:Organelles / Q000648:ultrastructure; D010280:Parathyroid Glands / Q000648:ultrastructure*
D002118:Calcium