title: The human keratinocyte cell line HaCaT: an in vitro cell culture model for keratinocyte testosterone metabolism.
authors.affiliation: Department of Pharmaceutics and Biopharmacy, Philipps-University, Marburg, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Altenburger
authors.forename: T
authors.initials: T
authors.lastname: Kissel
mesh_terms: D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase / Q000378:metabolism; D058891:5-alpha Reductase Inhibitors; D000279:Administration, Cutaneous; D000735:Androstenedione / Q000378:metabolism; D018931:Antineoplastic Agents, Hormonal / Q000378:metabolism / Q000493:pharmacokinetics*; D001378:Azasteroids / Q000494:pharmacology; D018929:Cell Culture Techniques / Q000379:methods; D002460:Cell Line; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D018120:Finasteride / Q000494:pharmacology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D015603:Keratinocytes / Q000166:cytology* / Q000187:drug effects / Q000201:enzymology*; D012867:Skin / Q000166:cytology / Q000378:metabolism; D013739:Testosterone / Q000031:analogs & derivatives / Q000378:metabolism / Q000493:pharmacokinetics*; D014316:Tritium / Q000493:pharmacokinetics
chemical_list: C090665:4,7beta-dimethyl-4-azacholestan-3-one; D058891:5-alpha Reductase Inhibitors; D018931:Antineoplastic Agents, Hormonal; D001378:Azasteroids; D004791:Enzyme Inhibitors; D014316:Tritium; D013739:Testosterone; D000735:Androstenedione; D018120:Finasteride; C013915:boldenone; D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase