title: PKS1, a substrate phosphorylated by phytochrome that modulates light signaling in Arabidopsis.
abstract: Plants constantly monitor their light environment in order to grow and develop optimally, in part through use of the phytochromes, which sense red/far-red light. A phytochrome binding protein, PKS1 (phytochrome kinase substrate 1), was identified that is a substrate for light-regulated phytochrome kinase activity in vitro. In vivo experiments suggest that PKS1 is phosphorylated in a phytochrome-dependent manner and negatively regulates phytochrome signaling. The data suggest that phytochromes signal by serine-threonine phosphorylation.
authors.affiliation: Plant Biology Laboratory, Howard Hughes Medical Institute, Salk Institute, La Jolla, CA 92037, USA.
authors.forename: C
authors.initials: C
authors.lastname: Fankhauser
authors.forename: K C
authors.initials: KC
authors.lastname: Yeh
authors.forename: J C
authors.initials: JC
authors.lastname: Lagarias
authors.forename: H
authors.initials: H
authors.lastname: Zhang
authors.forename: T D
authors.initials: TD
authors.lastname: Elich
authors.forename: J
authors.initials: J
authors.lastname: Chory
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism*; D029681:Arabidopsis Proteins; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D017343:Genes, Plant; D000071677:Histidine Kinase; D047908:Intracellular Signaling Peptides and Proteins; D008027:Light; D008565:Membrane Proteins; D008969:Molecular Sequence Data; D009154:Mutation; D010750:Phosphoproteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D010766:Phosphorylation; D010786:Photoreceptor Cells; D010834:Phytochrome / Q000378:metabolism*; D051942:Phytochrome A; D051939:Phytochrome B; D010940:Plant Proteins; D011494:Protein Kinases / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D015398:Signal Transduction; D014157:Transcription Factors
chemical_list: D029681:Arabidopsis Proteins; D002352:Carrier Proteins; D047908:Intracellular Signaling Peptides and Proteins; D008565:Membrane Proteins; C497973:PHYA protein, Arabidopsis; C497952:PHYB protein, Arabidopsis; C485609:PKS1 protein, Arabidopsis; C119522:PKS1 protein, plant; D010750:Phosphoproteins; D051942:Phytochrome A; D010940:Plant Proteins; D011993:Recombinant Fusion Proteins; D014157:Transcription Factors; D010834:Phytochrome; D051939:Phytochrome B; D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases; D000071677:Histidine Kinase