title: Asynchronous and asymmetric burst-suppression in a patient with a corpus callosum lesion.
abstract: BACKGROUND
  Burst suppression is seen in the electroencephalograms of patients receiving high doses of pentobarbital. In such circumstances, burst suppression is characterized by bilaterally synchronous and symmetric bursts of electrical activity followed by intervals of attenuation.
  
  
  METHODS
  We report on a case of asymmetric and asynchronous pentobarbital-induced burst suppression that occurred after a corpus callosum lesion sustained during trauma.
  
  
  CONCLUSIONS
  To our knowledge, this is the first such reported human case of asymmetric and asynchronous pentobarbital-induced burst suppression. These findings suggest that the corpus callosum may be involved in the synchronization of the burst-suppression pattern.
authors.affiliation: Comprehensive Epilepsy Center of the Hudson Valley Region at Westchester County Medical Center, Department of Neurology, New York Medical College, Valhalla 10595, USA.
authors.forename: C C
authors.initials: CC
authors.lastname: Lambrakis
authors.forename: M E
authors.initials: ME
authors.lastname: Lancman
authors.forename: C
authors.initials: C
authors.lastname: Romano
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology*; D003337:Corpus Callosum / Q000000981:diagnostic imaging / Q000503:physiopathology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D014057:Tomography, X-Ray Computed