title: [Possibilities of an open magnetic resonance scanner integration in therapy simulation and three-dimensional radiotherapy planning].
abstract: OBJECTIVE
  A system for digital integration of an open MR scanner (0.23 T, Figure 1) in therapy simulation and 3D radiation treatment planning is described.
  
  
  METHODS
  MR images were acquired using the body coil and various positioning and immobilization aids. A gradient echo sequence (TR/TE 320 ms/24 ms) was used to create axial and coronal data sets. Image distortions were measured and corrected using phantom measurements (Figure 2) and specially developed software.
  
  
  RESULTS
  Maximal and mean distortions of the MR images could be reduced from 19 mm to 8.2 mm and from 2.7 mm to 0.7 mm, respectively (Figure 3 to 5, Table 1). Coronal MR images were recalculated in fan beam projection for use at the therapy simulator. Tumor and organ contours were transferred from the MR image to the digitally acquired and corrected simulator image using a landmark matching algorithm (Figure 6 and 7). For 3D treatment planning, image fusion of axial MR images with standard CT planning images was performed using a landmark matching algorithm, as well (Figure 8). Representative cases are shown to demonstrate potential applications of the system.
  
  
  CONCLUSIONS
  The described system enables the integration of the imaging information from an open MR system in therapy simulation and 3D treatment planning. The low-field MR scanner is an attractive adjunct for the radio-oncologist because of the open design and the low costs.
authors.affiliation: Abteilung Klinische Radiologie und Poliklinik, Ruprecht-Karls-Universität Heidelberg.
authors.forename: K
authors.initials: K
authors.lastname: Schubert
authors.forename: F
authors.initials: F
authors.lastname: Wenz
authors.forename: R
authors.initials: R
authors.lastname: Krempien
authors.forename: O
authors.initials: O
authors.lastname: Schramm
authors.forename: G
authors.initials: G
authors.lastname: Sroka-Perez
authors.forename: P
authors.initials: P
authors.lastname: Schraube
authors.forename: M
authors.initials: M
authors.lastname: Wannenmacher
mesh_terms: D000465:Algorithms; D002283:Carcinoma, Bronchogenic / Q000532:radiotherapy; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008175:Lung Neoplasms / Q000532:radiotherapy; D008279:Magnetic Resonance Imaging; D019047:Phantoms, Imaging; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation; D018511:Systems Integration; D014057:Tomography, X-Ray Computed