title: Salt and hypertension in end-stage renal disease.
abstract: Salt and fluid overload play an important role in the pathogenesis of hypertension in patients with end-stage renal disease. However, in the individual patient, the relation between salt loading and blood pressure response is variable and appears to be influenced by various neurohumoral regulatory mechanisms. This may also have implications for the pathogenesis of structural cardiovascular abnormalities in patients with end-stage renal disease.
authors.forename: J P
authors.initials: JP
authors.lastname: Kooman
authors.forename: K M
authors.initials: KM
authors.lastname: Leunissen
authors.forename: A J
authors.initials: AJ
authors.lastname: Luik
mesh_terms: D002940:Circadian Rhythm; D004039:Diet, Sodium-Restricted; D004487:Edema / Q000209:etiology / Q000503:physiopathology; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000503:physiopathology; D017379:Hypertrophy, Left Ventricular / Q000209:etiology / Q000503:physiopathology; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000503:physiopathology; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000503:physiopathology; D009638:Norepinephrine / Q000502:physiology; D006435:Renal Dialysis / Q000009:adverse effects; D012084:Renin-Angiotensin System / Q000502:physiology; D012965:Sodium Chloride / Q000009:adverse effects*; D012982:Sodium, Dietary / Q000009:adverse effects*; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors / Q000502:physiology; D013564:Sympathetic Nervous System / Q000503:physiopathology; D014883:Water-Electrolyte Imbalance / Q000150:complications* / Q000503:physiopathology
chemical_list: D012982:Sodium, Dietary; D012965:Sodium Chloride; D000254:Sodium-Potassium-Exchanging ATPase; D009638:Norepinephrine