title: Primary polyarteritis nodosa presenting as acute symmetric quadriplegia.
abstract: We report a case of peripheral neuropathy presenting as acute symmetric areflexic quadriplegia in the setting of a well-defined clinical, histopathologic, and angiographic diagnosis of classic polyarteritis nodosa. While it is usually easy to recognize the typical clinical presentation of necrotizing angiopathy-induced peripheral neuropathy as a mononeuritis multiplex or a distal polyneuropathy in association with a collagen vascular disease, clinicians must be equally sensitive to a number of more challenging possibilities. Acute quadriplegia similar to that seen in Guillain-Barré syndrome can be secondary to primary classic polyarteritis nodosa and the former may be the chief or even the sole manifestation of the latter.
authors.affiliation: Internal Medicine Unit, Hospital Casa Maternitat, Corporació Sanitària Clínic, Barcelona, Spain.
authors.forename: X
authors.initials: X
authors.lastname: Bosch
authors.forename: M
authors.initials: M
authors.lastname: Navarro
authors.forename: A
authors.initials: A
authors.lastname: Lopez-Soto
authors.forename: J M
authors.initials: JM
authors.lastname: Grau
authors.forename: F
authors.initials: F
authors.lastname: Martinez-Orozco
mesh_terms: D000368:Aged; D000792:Angiography; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D009336:Necrosis; D010488:Polyarteritis Nodosa / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D011782:Quadriplegia / Q000175:diagnosis* / Q000209:etiology; D013497:Sural Nerve / Q000098:blood supply / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D003520:Cyclophosphamide; D011241:Prednisone