title: A new solid-phase support for oligonucleotide synthesis.
abstract: An alternative solid support for oligonucleotide synthesis was developed by coupling a polymer colloid to a modified polyethylene filter disc. The functions on the polymer colloid not used for attachment to the surface were derivatized with a Jeffamine diamine and loaded with appropriate deoxynucleoside succinates. The performance of this support system was evaluated and compared to existing resins.
authors.affiliation: FlowGenix Corporation, Webster, TX 77598, USA.
authors.forename: R V
authors.initials: RV
authors.lastname: Devivar
authors.forename: S L
authors.initials: SL
authors.lastname: Koontz
authors.forename: W J
authors.initials: WJ
authors.lastname: Peltier
authors.forename: J E
authors.initials: JE
authors.lastname: Pearson
authors.forename: T A
authors.initials: TA
authors.lastname: Guillory
authors.forename: J D
authors.initials: JD
authors.lastname: Fabricant
mesh_terms: D013058:Mass Spectrometry; D008956:Models, Chemical; D008967:Molecular Biology; D009841:Oligonucleotides / Q000138:chemical synthesis*; D011095:Polyethylenes / Q000737:chemistry*
chemical_list: D009841:Oligonucleotides; D011095:Polyethylenes