Mechanical properties of medical grade expanded polytetrafluoroethylene: the effects of internodal distance, density, and displacement rate.
Expanded polytetrafluoroethylene (e-PTFE) is used successfully in a multitude of biomedical and clinical applications. The success of this biomaterial is due to its microporous structure that allows biointegration for fixation, as well as overall mechanical integrity. The mechanical properties and degree of tissue ingrowth depend on the microstructure of the expanded polymer foam, yet little is known about the correlation of the internodal distance and other microstructural features with the monotonic tensile properties. Complete structure-property correlation can be used to provide invaluable knowledge for the design of biomedical devices. The purpose of this study was to investigate the monotonic tensile properties of e-PTFE over a range of medically relevant microstructural features and manufacturing parameters. The microstructural and manufacturing parameters considered were internodal distance, linear density, volumetric density, and reduction ratio. Additionally, the effect of displacement rate on mechanical properties was studied. We found that the ultimate stress and strain increased linearly with linear density (R2 = 0.88 and 0.67, respectively). Surprisingly, elastic modulus did not correlate with any parameter measured and only weak correlations were found between all properties and internodal distance. The yield and ultimate stresses increased with increasing displacement rate (R2 = 0.88 and 0.57, respectively). The findings from this study indicate that linear density is a better predictor of mechanical properties than internodal distance and may be the preferred parameter to control when specifying a material for implantation in load bearing situations.
Catanese
J
J
Joint Bioengineering Graduate Group, University of California, Berkeley, USA.
Cooke
D
D
Maas
C
C
Pruitt
L
L
D001672:Biocompatible Materials / Q000737:chemistry; D011138:Polytetrafluoroethylene / Q000737:chemistry
D001672:Biocompatible Materials; D011138:Polytetrafluoroethylene