title: Characteristics of frequency-of-seeing curves for a motion stimulus in glaucoma eyes, glaucoma suspect eyes, and normal eyes.
abstract: This study compared frequency-of-seeing curves for a line displacement test in glaucoma patients and normals. Probit analysis of the frequency-of-seeing curves provided the motion thresholds and the slopes of the frequency-of-seeing curves, represented by the interquartile range. The thresholds and interquartile ranges were significantly elevated in the glaucoma eyes and suspect eyes, compared to controls. A logistic regression model incorporating both the interquartile range and threshold significantly improved the sensitivity of the motion test in the suspects. Abnormal shallowing of the slope of the motion frequency-of-seeing curve may represent one of the earliest changes in glaucoma.
authors.affiliation: Institute of Ophthalmology, Department of Visual Science, London, UK.
authors.forename: M C
authors.initials: MC
authors.lastname: Westcott
authors.forename: F W
authors.initials: FW
authors.lastname: Fitzke
authors.forename: D P
authors.initials: DP
authors.lastname: Crabb
authors.forename: R A
authors.initials: RA
authors.lastname: Hitchings
mesh_terms: D000328:Adult; D000368:Aged; D005902:Glaucoma, Open-Angle / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D009039:Motion Perception / Q000502:physiology*; D011594:Psychometrics; D012372:ROC Curve; D012684:Sensory Thresholds / Q000502:physiology