Eye development: Notch lends a handedness.
The arrangement of photoreceptors in the ommatidia of the Drosophila compound eye is polarized, having a handedness or chirality. Notch signalling helps determine this handedness, first by establishing a signalling center at the eye equator, and second by mediating a choice between two photoreceptor fates
Blair
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Department of Zoology, University of Wisconsin, 250 N Mills Street, Madison, Wisconsin 53706, USA.
D000818:Animals; D004330:Drosophila / Q000196:embryology* / Q000235:genetics; D029721:Drosophila Proteins; D005123:Eye / Q000196:embryology* / Q000254:growth & development; D008565:Membrane Proteins / Q000378:metabolism*; D009154:Mutation; D017956:Photoreceptor Cells, Invertebrate / Q000378:metabolism; D051880:Receptors, Notch; D015398:Signal Transduction
D029721:Drosophila Proteins; D008565:Membrane Proteins; C497759:N protein, Drosophila; D051880:Receptors, Notch