title: Tracheobronchial stenting in patients with esophageal cancer involving the central airways.
abstract: OBJECTIVE
  Locoregional progression of esophageal cancer can result in respiratory distress aving to tracheoesophageal (T-E) fistula or central airways stenosis. We report our experience of airway stenting in 51 patients with esophageal carcinoma involving the central airways.
  
  
  METHODS
  All data were recorded retrospectively. Fifty-one patients (44 men and seven women), with a mean age of 58.6 years, were analyzed. All had an esophageal squamous cell carcinoma. Severe respiratory impairment due to tumor invasion or to a tracheobronchial fistula (n= 14) was present in all patients. Nine of the 14 patients with fistula had dysphagia. Among the 37 patients without fistula, 19 had dysphagia.
  
  
  RESULTS
  Sixty-six tracheobronchial stents were inserted in 51 patients: 65 Dumon stents and one Wallstent. Forty stents were implanted in the trachea, 16 in the left main bronchus and 10 in the right main bronchus. In 47 patients there was a significant improvement of respiratory symptoms. Esophageal intubation, carried out in nine patients, allowed eating and drinking in all cases. Mean survival was 107.7 days, with the longest follow-up 587 days. There was no difference between mean survival in the patients with fistulae (103.3+/-days) and the others (109.3+/-days). In two cases stent placement was responsible for death (massive hemoptysis and pneumonia). The main complications were migration (n=6), granuloma (n=2), pneumonia (n=2) and pneumothorax (n = 2). In 13 patients tumor progression in the airways was noted from one to 11 months after stenting, inducing a relapse of dyspnea.
  
  
  CONCLUSIONS
  Complications are easily detected by the appearance of respiratory symptoms and do not necessitate systematic flexible bronchoscopy, but only preventive measures such as regular aerosol therapy, adapted respiratory physiotherapy and regular clinical follow-up.
authors.affiliation: Pneumology Service, Centre Hospitalier Universitaire, Rennes, France.
authors.forename: C
authors.initials: C
authors.lastname: Belleguic
authors.forename: H
authors.initials: H
authors.lastname: Lena
authors.forename: E
authors.initials: E
authors.lastname: Briens
authors.forename: B
authors.initials: B
authors.lastname: Desrues
authors.forename: J F
authors.initials: JF
authors.lastname: Bretagne
authors.forename: P
authors.initials: P
authors.lastname: Delaval
authors.forename: J
authors.initials: J
authors.lastname: Kernec
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000473:pathology; D004938:Esophageal Neoplasms / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012131:Respiratory Insufficiency / Q000209:etiology*; D015607:Stents; D014138:Tracheoesophageal Fistula / Q000150:complications*; D016896:Treatment Outcome