[Immunological characteristics of patients with acute coronary syndrome (unstable angina and myocardial infarction)].
Admission and discharge values of rosette formation, adhesive and phagocytic ability of neutrophils, exercise tests with calculation of the tension index (TI), serum concentrations of IgG, IgA and IgM, circulating immune complexes (CIC) and cardiolipin antibodies (CAB) were studied in 48 males with unstable angina pectoris and acute myocardial infarction. Acute coronary syndrome is shown to be associated with marked immune alterations, primarily, with elevated levels of CIC and CAB, reduced TI. These alterations persisted for 3-5 weeks of the hospital stay and provoked the risk of repeated infarctions and thrombotic complications after relief of clinical symptoms of acute coronary failure.
Logacheva
I V
IV
Leshchinskiĭ
L A
LA
Zvorygin
I A
IA
D000789:Angina, Unstable / Q000097:blood / Q000276:immunology*; D017153:Antibodies, Anticardiolipin / Q000276:immunology; D000936:Antigen-Antibody Complex / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D005500:Follow-Up Studies; D006801:Humans; D007136:Immunoglobulins / Q000097:blood / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000276:immunology*; D009504:Neutrophils / Q000473:pathology; D010587:Phagocytosis; D011379:Prognosis; D012307:Risk Factors; D013577:Syndrome
D017153:Antibodies, Anticardiolipin; D000936:Antigen-Antibody Complex; D015415:Biomarkers; D007136:Immunoglobulins