title: [The cholesterol-lowering effect of black, carioquinha and red beans (Phaseolus vulgaris, L.) in hypercholesterolemic rats].
abstract: The propose of the present work was to investigate the cholesterol-lowering effect of black carioquinha and red beans (Phaseolus vulgaris, L.), widely consumed in Brazil, in hypercholesterolemic rats. Five groups of 8 male rats, Wistar strain, initial body weight of 200 g were kept at 25 degrees in a light-dark cycle of 12 h, for 28 days. The group Standard received a basal casein diet. Group Control was formulated by the addition of 1% cholesterol to the basal diet to produce hypercholesterolemia in the rats. The other groups received similar diets to the Control, substituted by 30% black (BB), carioquinha (CB) or red (RB) beans, on dry-weight. The addition of 1% cholesterol promoted an increase of 49% in the levels of total blood cholesterol on Control group, compared with the Standard. The bean diets reduced total blood cholesterol (non-significant): BB reduced 16%, RB 12% and CB 11%, in relation to the Control. The addition of cholesterol to the diets promoted lipid deposition in the rat livers, even in those fed the bean diets. It seems that the reduction of cholesterol in blood is followed by its retention in the rat livers.
authors.affiliation: Departamento de Nutrição e Saúde, Universidade Federal de Viçosa, Brasil.
authors.forename: C O
authors.initials: CO
authors.lastname: Rosa
authors.forename: N M
authors.initials: NM
authors.lastname: Costa
authors.forename: R M
authors.initials: RM
authors.lastname: Nunes
authors.forename: P F
authors.initials: PF
authors.lastname: Leal
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000097:blood*; D004032:Diet; D007887:Fabaceae; D006937:Hypercholesterolemia / Q000378:metabolism*; D008297:Male; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar
chemical_list: D002784:Cholesterol