[The detection of antibodies, antigens and circulating immune complexes in acute and chronic fascioliasis. Preliminary results].
24 patients with fascioliasis were studied. 19 of them were in the chronic stage and 5 in acute stage. The presence of antigens and of circulating immune complexes (CIC) was detected in 100% of the patients suffering from acute fascioliasis with less than 30 days of evolution of the clinical symptoms; whereas coproantigens were present in 100% of the chronic patients. In this group it was observed a considerable number of cases with elevated levels of antibodies. 43.7% of the cases with CIC were detected by using the precipitation technique with PEG and that of Clq deviation. A highly significant correlation was found between the eggs counting and the CIC levels by both techniques. Another important correlation was established between the eggs counting and the levels of coproantigens.
Pelayo
L
L
Instituto de Medicina Tropical Pedro Kourí, Ciudad de La Habana, Cuba.
Espino
A M
AM
Duménigo Ripoll
B E
BE
Finlay Villalvilla
C M
CM
D000208:Acute Disease; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D000936:Antigen-Antibody Complex / Q000097:blood*; D000947:Antigens, Helminth / Q000032:analysis*; D002908:Chronic Disease; D004797:Enzyme-Linked Immunosorbent Assay; D005210:Fasciola hepatica / Q000276:immunology*; D005211:Fascioliasis / Q000175:diagnosis* / Q000469:parasitology; D005243:Feces / Q000737:chemistry / Q000469:parasitology; D006801:Humans; D010270:Parasite Egg Count
D000909:Antibodies, Helminth; D000936:Antigen-Antibody Complex; D000947:Antigens, Helminth