Evaluation of a multidimensional measure of dyspepsia-related health for use in a randomized clinical trial.
In previous work, we developed a multidimensional measure of dyspepsia-related health. To evaluate the adequacy of this instrument as an outcome measure for a large-scale, multicenter, randomized clinical trial, we used Rasch analysis to address three questions: (1) Are the scales interval-level? (2) Do the scales measure precisely across the entire range of dyspepsia outcomes? (3) Do the scales' items have an optimal number of response categories? We found that the scales were not interval-level and that they did not measure effectively at low or high levels of the dyspepsia-related outcomes. Our results also suggest that patients were capable of discriminating among only four- to seven-item response categories. Further studies are needed to identify items that effectively measure high and low levels of dyspepsia-related outcomes and to validate that decreasing the number of response categories improves the psychometric properties of these scales.
Cook
K F
KF
Department of Veterans Affairs Health Services Research and Development Field Program, Veterans Affairs Medical Center, Houston, TX 77030, USA.
Rabeneck
L
L
Campbell
C J
CJ
Wray
N P
NP
D000328:Adult; D004415:Dyspepsia / Q000209:etiology / Q000628:therapy*; D005260:Female; D006305:Health Status Indicators; D006787:Hospitals, Veterans; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D017063:Outcome Assessment, Health Care / Q000379:methods* / Q000592:standards; D010044:Outpatient Clinics, Hospital; D011594:Psychometrics; D016032:Randomized Controlled Trials as Topic; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013781:Texas; D016896:Treatment Outcome