Immunity in experimental murine filariasis: roles of T and B cells revisited.
We have reevaluated the contributions of T and B cells in Brugia malayi infection by utilizing knockout mice on a uniform background (C57BL/6J). We find that B-cell-deficient mice are more permissive to infection than T-cell-deficient mice.
Babu
S
S
University of Connecticut Health Center, Farmington, Connecticut, USA.
Shultz
L D
LD
Klei
T R
TR
Rajan
T V
TV
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D017178:Brugia malayi / Q000276:immunology*; D004195:Disease Models, Animal; D005368:Filariasis / Q000276:immunology*; D007109:Immunity; D051379:Mice; D008810:Mice, Inbred C57BL; D013601:T-Lymphocytes / Q000276:immunology*