title: [The antidiphtheria and antitetanus immunities of children of the Maritime Territory after the use of adsorbed DTP vaccine and adsorbed DT-m anatoxin].
abstract: The state of collective immunity to diphtheria and tetanus in children of preschool age, depending on the kind of vaccine preparation used for immunization, was studied. The immunological potency of adsorbed DPT vaccine (i.e. its capacity of forming prolonged and stable basic immunity) was shown to be higher in comparison with the potency of adsorbed DT toxoid with reduced antigen content (DT-R). The study revealed that in all groups of children the level of antitetanus immunity was higher than the level of antidiphtheria immunity, and 3 years later its decrease was less pronounced. A stricter approach to giving medical grounds for the use of low-reactive adsorbed DT-R in the immunization of children belonging to groups of risk is recommended.
authors.affiliation: Research Institute of Epidemiology and Microbiology, Head Office of Public Health of the Administration of the Maritime Territory, Vladivostok, Russia.
authors.forename: T S
authors.initials: TS
authors.lastname: Zaporzhets
authors.forename: I G
authors.initials: IG
authors.lastname: Lunika
authors.forename: L K
authors.initials: LK
authors.lastname: Greben'kova
authors.forename: N A
authors.initials: NA
authors.lastname: Belogolovkina
authors.forename: I D
authors.initials: ID
authors.lastname: Makarenkova
authors.forename: N N
authors.initials: NN
authors.lastname: Besednova
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood; D000917:Antibody Formation; D000918:Antibody Specificity; D002648:Child; D002675:Child, Preschool; D003017:Clostridium tetani / Q000276:immunology; D003353:Corynebacterium diphtheriae / Q000276:immunology; D004165:Diphtheria / Q000517:prevention & control*; D004168:Diphtheria Toxoid / Q000276:immunology*; D022422:Diphtheria-Tetanus Vaccine; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000276:immunology*; D006801:Humans; D007115:Immunization Schedule; D012800:Siberia; D013742:Tetanus / Q000517:prevention & control*; D013745:Tetanus Toxoid / Q000276:immunology*; D013997:Time Factors; D017778:Vaccines, Combined / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D004168:Diphtheria Toxoid; D022422:Diphtheria-Tetanus Vaccine; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D013745:Tetanus Toxoid; D017778:Vaccines, Combined