title: Progress in protein structure prediction: assessment of CASP3.
abstract: The third comparative assessment of techniques of protein structure prediction (CASP3) was held during 1998. This is a blind trial in which structures are predicted prior to having knowledge of the coordinates, which are then revealed to enable the assessment. Three sections at the meeting evaluated different methodologies - comparative modelling, fold recognition and ab initio methods. For some, but not all of the target coordinates, high quality models were submitted in each of these sections. There have been improvements in prediction techniques since CASP2 in 1996, most notably for ab initio methods.
authors.affiliation: Biomolecular Modelling Laboratory, Imperial Cancer Research Fund, London, UK. m.sternberg@icrf.icnet.uk
authors.forename: M J
authors.initials: MJ
authors.lastname: Sternberg
authors.forename: P A
authors.initials: PA
authors.lastname: Bates
authors.forename: L A
authors.initials: LA
authors.lastname: Kelley
authors.forename: R M
authors.initials: RM
authors.lastname: MacCallum
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D019295:Computational Biology / Q000379:methods* / Q000639:trends; D008958:Models, Molecular; D011487:Protein Conformation; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry*; D012984:Software
chemical_list: D011506:Proteins