Development of a chronic chromoblastomycosis model in immunocompetent mice.
An experimental model to study chromoblastomycosis caused by Fonsecaea pedrosoi was developed in immunocompetent BALB/c mice. Unlike previous models of chromoblastomycosis, in this model a chronic, progressive infection mimicking the infection in humans was developed. This model may be suitable for use in experimental studies of chromoblastomycosis.
Cardona-Castro
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Laboratorio de Microbiologia, Instituto Colombiano de Medicina Tropical, Medellin, Colombia. icmt@epm.net.co
Agudelo-Flórez
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D000818:Animals; D001203:Ascomycota / Q000302:isolation & purification; D002862:Chromoblastomycosis / Q000382:microbiology* / Q000473:pathology; D004195:Disease Models, Animal; D006801:Humans; D007121:Immunocompetence; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D012867:Skin / Q000382:microbiology / Q000473:pathology