title: Fatal Clostridium sordellii ischio-rectal abscess with septicaemia complicating ultrasound-guided transrectal prostate biopsy.
abstract: Clostridium sordellii is a Gram-positive spore-forming anaerobic bacillus rarely encountered in human infection. A case of C. sordellii ischio-rectal abscess with rapidly fatal septicaemia is described which complicated ultrasound-guided transrectal biopsy of the prostate, despite ciprofloxacin prophylaxis. Neither C. sordellii ischio-rectal abscess nor ischio-rectal abscess complicating transrectal biopsy have been reported previously. Judging from our experience and the reviewed literature, the addition of prophylactic anti-anaerobe drugs should be strongly considered until an optimal prophylactic regimen will be defined by randomized controlled trials.
authors.affiliation: Infectious Disease Institute, Soroka Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Borer
authors.forename: J
authors.initials: J
authors.lastname: Gilad
authors.forename: E
authors.initials: E
authors.lastname: Sikuler
authors.forename: K
authors.initials: K
authors.lastname: Riesenberg
authors.forename: F
authors.initials: F
authors.lastname: Schlaeffer
authors.forename: D
authors.initials: D
authors.lastname: Buskila
mesh_terms: D000038:Abscess / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis; D000368:Aged; D000667:Ampicillin / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000150:complications / Q000188:drug therapy; D001706:Biopsy / Q000009:adverse effects; D002939:Ciprofloxacin / Q000627:therapeutic use; D003013:Clostridium / Q000472:pathogenicity*; D003015:Clostridium Infections / Q000150:complications* / Q000628:therapy; D004232:Diuretics / Q000627:therapeutic use; D017809:Fatal Outcome; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D007512:Ischium / Q000473:pathology; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D010406:Penicillins / Q000627:therapeutic use; D011467:Prostate / Q000473:pathology; D011471:Prostatic Neoplasms / Q000150:complications* / Q000175:diagnosis; D012002:Rectal Diseases / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D012007:Rectum / Q000000981:diagnostic imaging / Q000473:pathology; D014463:Ultrasonography
chemical_list: D000890:Anti-Infective Agents; D004232:Diuretics; D010406:Penicillins; D008795:Metronidazole; D002939:Ciprofloxacin; D000667:Ampicillin; D005665:Furosemide