title: Recurrent chondrosarcoma of the cranial base: a durable response to ifosfamide-doxorubicin chemotherapy.
abstract: The case of a 46-year old woman with recurrent chondrosarcoma of the cranial base, refractory to neurosurgical intervention and external radiotherapy is reported. She received five cycles of systemic chemotherapy utilizing ifosfamide and doxorubicin which resulted in a durable clinical and radiographic response lasting 52+ months. A review of the management options for recurrent chondrosarcoma of the cranial base is also presented.
authors.affiliation: Kentuckiana Medical Oncology Associates, Louisville, USA.
authors.forename: R V
authors.initials: RV
authors.lastname: La Rocca
authors.forename: K W
authors.initials: KW
authors.lastname: Morgan
authors.forename: K
authors.initials: K
authors.lastname: Paris
authors.forename: T R
authors.initials: TR
authors.lastname: Baeker
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002813:Chondrosarcoma / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery
chemical_list: D004317:Doxorubicin; D007069:Ifosfamide