Candida parapsilosis: an unusual organism causing prosthetic heart valve infective endocarditis.
We report a case of Candida parapsilosis prosthetic heart valve infective endocarditis in a 67-year-old man. The infection was successfully treated with liposomal amphotericin B (AmBisome) and flucytosine. Surgical replacement of the infected valve was necessary. Recurrence was prevented with oral fluconazole 400mg daily as maintenance therapy. The patient remained well after 2 years of follow-up.
Darwazah
A
A
Department of Cardiothoracic Surgery, Western Infirmary, Glasgow, Scotland, UK.
Berg
G
G
Faris
B
B
D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001021:Aortic Valve; D002097:C-Reactive Protein / Q000032:analysis; D002175:Candida / Q000472:pathogenicity*; D002177:Candidiasis / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004452:Echocardiography; D004696:Endocarditis / Q000188:drug therapy*; D005437:Flucytosine / Q000627:therapeutic use; D006350:Heart Valve Prosthesis / Q000382:microbiology*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D010138:Pacemaker, Artificial
D000935:Antifungal Agents; D000666:Amphotericin B; D002097:C-Reactive Protein; D005437:Flucytosine