Hydroxyurea-induced acute interstitial pneumonitis in a patient with essential thrombocythemia.
Hydroxyurea is a drug widely used to control myeloproliferative disorders, due in part to its relative lack of severe side effects. We present a case of acute interstitial pneumonitis in a patient who was treated with hydroxyurea for essential thrombocythemia. The clinical course suggests that the interstitial pneumonitis was induced by hydroxyurea. This is the first case of hydroxyurea-induced acute interstitial pneumonitis reported in the literature.
Quintás-Cardama
A
A
Department of Hematology, Hospital Xeral de Galicia, Complexo Hospitalario Universitario de Santiago de Compostela, La Coruña, Spain.
Pérez-Encinas
M
M
Gonzalez
S
S
Bendaña
A
A
Bello
J L
JL
D006801:Humans; D006918:Hydroxyurea / Q000009:adverse effects* / Q000627:therapeutic use; D017563:Lung Diseases, Interstitial / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D013920:Thrombocythemia, Essential / Q000150:complications* / Q000188:drug therapy
D006918:Hydroxyurea