title: [Double cancer observed from bladder cancer].
abstract: BACKGROUND
  In recent years, despite of the improvement of treatment results for cancer and long life, the occurrence of second primary cancer was increased. In this paper, we analyzed present condition of double cancer observed with bladder cancer in our hospital.
  
  
  METHODS
  Last 21 years, we have treated 969 cases (828 male and 141 female) of primary bladder cancer. For those cases, we analyzed in term of frequency, involved organ, age, interval between two cancer occurrence, risk factor and prognosis of double cancer patients.
  
  
  RESULTS
  Of 969 cases with bladder cancer, 81 cases (8.36%) had double cancer involving 6 cases (0.61%) of triple cancer. In sex, 70 males (9.78%) and 11 females (7.80%) had double cancer. As involved organs, 25 cases (3.02%) had in prostate, 23 cases (2.37%) in stomach, 3 case (2.13%) in breast, 14 cases (1.44%) in colon and rectum. In diagnosis timing of complicated cancer from bladder cancer, 28 cases (34.6%) were diagnosed previously to bladder, 28 cases (34.6%) were simultaneously and 31 cases (38.3%) were secondary. An average interval of diagnosis of two cancer were 49 +/- 42.5 months. An average age of occurrence of second cancer was 70.3 +/- 8.8 years. Actual survival rate from diagnosis of bladder cancer were 90.8%, 68.6%, 53.3% and 30.3%, after 1, 3, 5 and 10 years, respectively. Ten cases were dead by bladder cancer, 21 cases by complicated cancer and 16 cases by another cause.
  
  
  CONCLUSIONS
  The incidence of double cancer with bladder cancer were increased. Prostate cancer, colorectal cancer and breast cancer were gradually increased as complicated organs in Japan. The prognosis of double cancer patients with bladder cancer was poor than single bladder cancer patients.
authors.affiliation: Department of Urology, Kanagawa Prefectural Atsugi Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Tashiro
authors.forename: S
authors.initials: S
authors.lastname: Iwamuro
authors.forename: T
authors.initials: T
authors.lastname: Hatano
authors.forename: A
authors.initials: A
authors.lastname: Furuta
authors.forename: A
authors.initials: A
authors.lastname: Takizawa
authors.forename: Y
authors.initials: Y
authors.lastname: Ohishi
authors.forename: H
authors.initials: H
authors.lastname: Igarashi
authors.forename: N
authors.initials: N
authors.lastname: Hasegawa
authors.forename: K
authors.initials: K
authors.lastname: Asano
authors.forename: H
authors.initials: H
authors.lastname: Aoki
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000628:therapy; D015179:Colorectal Neoplasms / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology; D016609:Neoplasms, Second Primary / Q000453:epidemiology; D011379:Prognosis; D012307:Risk Factors; D001749:Urinary Bladder Neoplasms / Q000628:therapy