Familial dyskeratotic comedones.
We report a 49-year-old white woman having asymptomatic hyperkeratotic comedone-like lesions on her legs, arms and trunk. Her sister is similarly affected, but less severely. The clinical and histopathological features indicated a diagnosis of familial dyskeratotic comedones, a rare autosomal dominant condition.
Van Geel
N A
NA
University Hospital Maastricht, P.Debyelaan 25, 6202 AZ Maastricht, The Netherlands.
Kockaert
M
M
Neumann
H A
HA
D001132:Arm / Q000473:pathology; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D007642:Keratosis / Q000235:genetics* / Q000473:pathology; D007868:Leg Dermatoses / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged; D012867:Skin / Q000473:pathology*; D013909:Thorax / Q000473:pathology