Prenylagaramides A and B, new cyclic peptides from two strains of oscillatoria agardhii
Prenylagaramides A (1) and B (2), two new cyclic peptides, were isolated from the cultured cyanobacteria Oscillatoria agardhii (NIES-205) and O. agardhii (NIES-596), respectively. The structures of 1 and 2, which both contain a rare O-prenyltyrosine (Ptyr) unit, were established as cyclo(-Ptyr1-Gly2-Thr3-Gly4-Glu5-Phe6-Phe7-Asn8-Pro9-) and cyclo(-Ptyr1-Leu2-Tyr3-Pro4-Ile5-Asn6-Pro7-), respectively, by spectroscopic analysis and chemical degradation.
Murakami
M
Laboratory of Marine Biochemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Itou
Y
Ishida
K
Shin
HJ