title: Interobserver agreement for grating acuity and letter acuity assessment in 1- to 5.5-year-olds with severe retinopathy of prematurity.
abstract: OBJECTIVE
  To evaluate interobserver test-retest reliability of the Teller Acuity Card procedure for assessment of grating acuity at ages 1, 2, 3.5, 4.5, and 5.5 years, for HOTV letter acuity at 3.5 and 4.5 years, and for Early-Treatment Diabetic Retinopathy Study (ETDRS) letter acuity at 5.5 years in the multicenter study of Cryotherapy for Retinopathy of Prematurity (CRYO-ROP).
  
  
  METHODS
  Subjects were the 73 participants in the CRYO-ROP study who had acuity assessed at one or more ages by two of the seven study visual acuity testers as part of a quality control procedure. All subjects had birth weights of less than 1251 g, and all had severe (threshold) ROP in one or both eyes.
  
  
  RESULTS
  For sighted eyes, interobserver agreement for grating acuity (across all five test ages) was 0.5 octave or better in 57% of eyes and 1.0 octave or better in 85% of eyes. Interobserver agreement for letter acuity (3.5-, 4.5-, and 5.5-year test ages) was 0.5 octave or better in 71% of eyes and 1.0 octave or better in 93% of eyes. For all eyes (sighted and blind), Kendall rank correlation coefficients (Tau) were 0.86, 0.83, and 0.94 for grating, HOTV, and ETDRS acuity, respectively. Kappa statistics on data from all eyes indicated excellent interobserver agreement for grating, HOTV, and ETDRS acuity (0.73, 0.80, and 0.84, respectively). Interobserver agreement was not related to age or to severity of retinal residua of ROP.
  
  
  CONCLUSIONS
  Excellent interobserver agreement for grating acuity measurements and for letter acuity measurements was obtained. Results suggest that with careful training and implementation of quality control procedures, high reliability of visual acuity results is possible in clinical populations of young children.
authors.affiliation: Department of Ophthalmology, University of Arizona, Tucson 85719-3758, USA.
authors.forename: E M
authors.initials: EM
authors.lastname: Harvey
authors.forename: V
authors.initials: V
authors.lastname: Dobson
authors.forename: B
authors.initials: B
authors.lastname: Tung
authors.forename: G E
authors.initials: GE
authors.lastname: Quinn
authors.forename: R J
authors.initials: RJ
authors.lastname: Hardy
mesh_terms: D002648:Child; D002675:Child, Preschool; D003452:Cryosurgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D015588:Observer Variation; D015203:Reproducibility of Results; D012178:Retinopathy of Prematurity / Q000503:physiopathology* / Q000601:surgery; D014787:Vision Tests / Q000379:methods*; D014792:Visual Acuity / Q000502:physiology