title: Primary antiphospholipid syndrome: a cause of catastrophic shunt thrombosis in the newborn.
abstract: This is a unique report of systemic-to-pulmonary artery shunt thromboses secondary to primary antiphospholipid syndrome and antithrombin III deficiency in a neonate with cyanotic congenital heart disease. This infant with tricuspid atresia experienced thromboses of two modified Blalock-Taussig shunts en route to a bidirectional cavo-pulmonary shunt and potential future Fontan operation. Chronic warfarin anticoagulation has prevented additional thrombo-embolic events.
authors.affiliation: Children's Heart Center, Winnipeg, Manitoba, USA.
authors.forename: C
authors.initials: C
authors.lastname: Deally
authors.forename: B J
authors.initials: BJ
authors.lastname: Hancock
authors.forename: N
authors.initials: N
authors.lastname: Giddins
authors.forename: L
authors.initials: L
authors.lastname: Hawkins
authors.forename: J
authors.initials: J
authors.lastname: Odim
mesh_terms: D016736:Antiphospholipid Syndrome / Q000150:complications*; D020152:Antithrombin III Deficiency / Q000150:complications; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011183:Postoperative Complications / Q000209:etiology*; D011651:Pulmonary Artery / Q000601:surgery; D013927:Thrombosis / Q000209:etiology*; D018785:Tricuspid Atresia / Q000150:complications / Q000601:surgery