A new solid-phase support for oligonucleotide synthesis.
An alternative solid support for oligonucleotide synthesis was developed by coupling a polymer colloid to a modified polyethylene filter disc. The functions on the polymer colloid not used for attachment to the surface were derivatized with a Jeffamine diamine and loaded with appropriate deoxynucleoside succinates. The performance of this support system was evaluated and compared to existing resins.
Devivar
R V
RV
FlowGenix Corporation, Webster, TX 77598, USA.
Koontz
S L
SL
Peltier
W J
WJ
Pearson
J E
JE
Guillory
T A
TA
Fabricant
J D
JD
D013058:Mass Spectrometry; D008956:Models, Chemical; D008967:Molecular Biology; D009841:Oligonucleotides / Q000138:chemical synthesis*; D011095:Polyethylenes / Q000737:chemistry*
D009841:Oligonucleotides; D011095:Polyethylenes