Excessive infantile growth and early pubertal growth spurt: typical features in patients with aspartylglycosaminuria.
Rapid infantile growth was the first clinical sign in patients (n = 51) with aspartylglycosaminuria, a lysosomal storage disorder. Even if young children with aspartylglycosaminuria were tall for their age, an early but weak pubertal growth spurt in both sexes resulted in reduced adult heights.
Arvio
P
P
Hospital for Children and Adolescents, Pediatric Neurology, Pediatric Endocrinology, and Pediatric Radiology, University of Helsinki, Helsinki, Finland.
Arvio
M
M
Marttinen
E
E
Sipilä
I
I
Pirinen
S
S
D000117:Acetylglucosamine / Q000031:analogs & derivatives* / Q000652:urine; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005387:Finland; D006128:Growth; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016464:Lysosomal Storage Diseases / Q000503:physiopathology* / Q000652:urine; D008297:Male; D008572:Menarche; D011627:Puberty / Q000502:physiology*
C000009:N-acetylglucosaminylasparagine; D000117:Acetylglucosamine