title: Rods induce transient tritanopia in blue cone monochromats.
abstract: Transient tritanopia is a cone-cone post-receptoral interaction between short-wavelength (S) cones and medium (M) and long (L) wavelength cones. Blue cone monochromats have rods and S cones of normal sensitivity but lack functional M/L cones. All blue cone monochromats tested (n = 8) show significant amounts of transient tritanopia mediated by rods. Attempts to find a similar rod-S cone interaction while silencing the L/M cones in normals yielded only a small amount of S cone sensitivity loss. The results suggest an exaggerated influence of rods on the S cone pathway in the retina of blue cone monochromats.
authors.affiliation: School of Optometry, University of California at Berkeley 94720-2020, USA. ghp@spectacle.berkeley.edu
authors.forename: G
authors.initials: G
authors.lastname: Haegerstrom-Portnoy
authors.forename: W A
authors.initials: WA
authors.lastname: Verdon
mesh_terms: D000221:Adaptation, Ocular; D000293:Adolescent; D000328:Adult; D003117:Color Vision Defects / Q000235:genetics / Q000503:physiopathology*; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D009434:Neural Pathways; D017949:Retinal Cone Photoreceptor Cells / Q000503:physiopathology; D017948:Retinal Rod Photoreceptor Cells / Q000503:physiopathology*; D012684:Sensory Thresholds / Q000502:physiology; D013053:Spectrophotometry