title: Drowning due to cyclobenzaprine and ethanol.
abstract: The deceased was a 35 year old female who was found by her husband in the bathtub with her head and face submerged in the water. Autopsy findings were unremarkable. Toxicological analysis revealed the presence of ethanol (215 mg/dL) and cyclobenzaprine (1.786 mg/l) in the blood. This high concentration of cyclobenzaprine (Flexeril) in combination with alcohol proved to be fatal.
authors.affiliation: Pittsburgh Criminalistics Laboratory, PA 15219, USA.
authors.forename: C L
authors.initials: CL
authors.lastname: Winek
authors.forename: W W
authors.initials: WW
authors.lastname: Wahba
authors.forename: C L
authors.initials: CL
authors.lastname: Winek
mesh_terms: D000061:Accidents, Home; D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects* / Q000097:blood; D000639:Amitriptyline / Q000031:analogs & derivatives* / Q000097:blood / Q000506:poisoning; D001344:Autopsy / Q000379:methods*; D001494:Baths / Q000009:adverse effects*; D002423:Cause of Death; D004332:Drowning / Q000097:blood / Q000209:etiology*; D004357:Drug Synergism; D000431:Ethanol / Q000097:blood / Q000506:poisoning*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D009125:Muscle Relaxants, Central / Q000097:blood / Q000506:poisoning*
chemical_list: D009125:Muscle Relaxants, Central; D000639:Amitriptyline; D000431:Ethanol; C004704:cyclobenzaprine