Search for related substances in market products containing enalapril maleate as the active principle.
This study's main object was the determination of substances, by means of high-performance liquid chromatography (HPLC), that are related to enalapril maleate in medicinal tablets. The research was on products containing a 20 mg active principle with a 12-month delta t and on those batches near their expiration date with an enalapril maleate concentration of 10, 5, and 2.5 mg.
Pilatti
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Instituto Nacional de Medicamentos, Administración Nacional de Medicamentos, Alimentos y Tecnología Médica (ANMAT), Buenos Aires, Argentina.
Ercolano
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Torre
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Chiale
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Spinetto
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D000959:Antihypertensive Agents; D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D004656:Enalapril; D013607:Tablets / Q000737:chemistry*; D013997:Time Factors
D000959:Antihypertensive Agents; D013607:Tablets; D004656:Enalapril