Cardiopulmonary dysfunction during minimally invasive thoraco-lumboendoscopic spine surgery.
The endoscopic retroperitoneal approach to thoracolumbar anterior spine fusion is associated with CO2 insufflation into the thoracic space. We studied the cardiopulmonary effects of this CO2 thoraco-retroperitoneal insufflation compared with the conventional open surgical procedure using thoraco-phreno-lumbotomy in 12 pigs under balanced anesthesia, paralysis, and mechanical ventilation. During open surgery of the thoracolumbar spine, animals exhibited unchanged systemic and pulmonary hemodynamics, as well as ventilation and oxygenation variables. Animals retroperitoneally insufflated with CO2 (12 mm Hg) exhibited a significant increase of PaCO2 and a moderate decrease of PaO2, SaO2, and pH, with insignificant changes of central venous filling pressures and systemic hemodynamics. Endoscopic phrenotomy with thoracic CO2 insufflation instantaneously and drastically affected hemodynamic status and pulmonary gas exchange with marked hypoxia, hypercapnia, systemic hypotension, tachycardia, and pulmonary hypertension within minutes. An increase of minute ventilation, inspiratory oxygen fraction, and positive end-expiratory pressure promptly reversed these cardiopulmonary effects. CO2 evacuation allowed the animals to completely recover and regain almost baseline cardiopulmonary status, except for a reduced arterial blood pressure. Appropriate monitoring and immediate CO2 desufflation may be beneficial in cases of therapy-resistant hemodynamic, oxygenation, and ventilation difficulties.


CONCLUSIONS
For endoscopic thoraco-lumbar spine fusion, CO2 thoraco-retroperitoneum-induced cardiopulmonary dysfunction must be of concern, especially in patients with cardiopulmonary compromise. Appropriate monitoring and immediate CO2 desufflation may be beneficial in cases of therapy-resistant hemodynamic, oxygenation, and ventilation difficulties.
Vollmar
B
B
Institute for Clinical & Experimental Surgery, University of Saarland, Homburg/Saar, Germany. vollmar@cbr.med.harvard.edu
Olinger
A
A
Hildebrandt
U
U
Menger
M D
MD
D000818:Animals; D001784:Blood Gas Analysis; D002245:Carbon Dioxide; D004724:Endoscopy / Q000009:adverse effects*; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006331:Heart Diseases / Q000209:etiology / Q000503:physiopathology; D006439:Hemodynamics; D008168:Lung / Q000503:physiopathology*; D008171:Lung Diseases / Q000209:etiology / Q000503:physiopathology; D008297:Male; D012121:Respiration, Artificial; D012129:Respiratory Function Tests; D013123:Spinal Fusion; D013131:Spine / Q000601:surgery*; D013552:Swine
D002245:Carbon Dioxide