title: Histologic and clinical evaluation of combined eyelid erbium: YAG and CO2 laser resurfacing.
abstract: OBJECTIVE
  To report the histopathologic and clinical effects of eyelid resurfacing that combines two different lasers.
  
  
  METHODS
  A case series of 23 patients who underwent eyelid resurfacing with two passes of the Erbium:YAG laser followed by one pass of the CO2 laser. With the Student t test, we compared skin re-epithelialization time and duration of erythema with those of a previous group of 25 patients who had undergone eyelid resurfacing with only the CO2 laser (two passes). A pathologist evaluated all skin biopsy specimens.
  
  
  RESULTS
  Combining both lasers shortened re-epithelialization time (7 vs 12 days, P = .04) and the duration of erythema (2.5 vs 7.0 weeks, P = .02). Histopathologic examination disclosed less coagulative dermal damage with the combined laser protocol.
  
  
  CONCLUSIONS
  The different biophysical properties of these two lasers can be combined in a periorbital resurfacing protocol to minimize both clinical and histopathologic morbidity.
authors.affiliation: Department of Ophthalmology, Mount Sinai Medical Center, New York, New York, USA.
authors.forename: A L
authors.initials: AL
authors.lastname: Millman
authors.forename: G E
authors.initials: GE
authors.lastname: Mannor
mesh_terms: D019882:Blepharoplasty / Q000379:methods*; D005143:Eyelids / Q000473:pathology* / Q000601:surgery; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D015361:Rhytidoplasty / Q000379:methods; D012867:Skin / Q000473:pathology