[Diagnostic difficulties of transfusion incidents due to bacterial contamination: report of two cases].
The French hemovigilance system has recently underlined the relative frequency of transfusion-associated bacterial sepsis and the necessity to remain constantly aware of this eventuality. We describe the experience of a hematology unit over a 18-month period: 189 acute transfusion reactions were registered and bacterial cultures of the implicated cellular blood products realized in 82 of them. A positive result was obtained in two cases. For both cases, clinical symptoms of transfusion reaction were limited to a lasting fever, and a skin rash occurred in aplastic patients with preexisting signs of sepsis. The causal relationship between this contamination and the transfusion reaction is difficult to establish. Clinical manifestations justifying a bacterial inquiry must therefore be more precisely defined, particularly in multitransfused patients.
Renom
P
P
Laboratoire d'hématologie, Hôpital C. Huriez, Lille, France.
Wibaut
B
B
Savage
C
C
Vannier
V
V
Goudemand
J
J
D000328:Adult; D001769:Blood / Q000382:microbiology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D018805:Sepsis / Q000382:microbiology / Q000635:transmission*; D065227:Transfusion Reaction