[Ser/Thr-phosphatases from bovine retina: detection of cDNA coding for the catalytic subunit of the gamma-isoform PP2B and two homologs of rdgC/PPEF].
The expression of genes for Ser/Thr phosphatases of the PP1/2A/2B class in the bovine retina was analyzed using PCR on cDNA. The mRNAs were found for the following phosphatases: PP1 (alpha- and gamma-isoforms), PP2A (alpha- and beta-isoforms), PPV, and PP2B (beta- and gamma-isoforms). Earlier, PP2B gamma-isoform was considered testis-specific. cDNAs of two phosphatases related to rdgC/PPEF were also detected. Thus, there are mRNAs of at least four phosphatases in retina that may be regulated by Ca2+.
Kutuzov
M A
MA
Laboratoire de Biophysique Moléculaire & Cellulaire, URA CNRS 520, Grenoble, France.
Andreeva
A V
AV
Pages
F
F
Bennett
N
N
D000595:Amino Acid Sequence; D000818:Animals; D019703:Calcineurin / Q000235:genetics / Q000378:metabolism*; D020134:Catalytic Domain; D002417:Cattle; D018076:DNA, Complementary; D008969:Molecular Sequence Data; D010749:Phosphoprotein Phosphatases / Q000235:genetics / Q000378:metabolism*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D012160:Retina / Q000201:enzymology*
D018076:DNA, Complementary; D012333:RNA, Messenger; D019703:Calcineurin; D010749:Phosphoprotein Phosphatases