[Melatonin lowers the threshold of light sensitivity of the human retina].
After chronic use of melatonin (3 mg before night-time for 14 days) campimetry showed a significant decrease of the threshold of brilliance sensitiveness of the retina in the absence of authentic changes of the sensorimotor response latency in individuals of the older age group. A connection between the eye light sensitivity and the direct effect of the hormone on the photoreceptors is suggested.
Arushanian
E B
EB
Department of Pharmacology, Stavropol State Medical Academy, Russia.
Ovanesov
K B
KB
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000368:Aged; D000375:Aging / Q000187:drug effects / Q000502:physiology; D003119:Color Perception Tests; D003864:Depression, Chemical; D005260:Female; D006801:Humans; D008027:Light; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D008875:Middle Aged; D012160:Retina / Q000187:drug effects* / Q000502:physiology; D012684:Sensory Thresholds / Q000187:drug effects; D012727:Sex Characteristics; D016037:Single-Blind Method; D058609:Visual Field Tests; D014796:Visual Perception / Q000187:drug effects*
D000276:Adjuvants, Immunologic; D008550:Melatonin