title: Emergence of mupirocin resistance in multiresistant Staphylococcus aureus clinical isolates belonging to Brazilian epidemic clone III::B:A.
abstract: Mupirocin is a topical antimicrobial agent that has been successfully used to eradicate methicillin-resistant Staphylococcus aureus from the anterior nares and other sites of patients and health care personnel. This report describes the acquisition of a novel mupirocin resistance gene (ileS) by an epidemic MRSA clone that is geographically widespread in Brazil.
authors.affiliation: Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Prof. Paulo de Góes, Laboratório de Biologia Molecular de Bactérias, Centro de Ciěncias da Saúde, Bloco I, Cidade Universitária, Rio de Janeiro, RJ 21941.590, Brazil.
authors.forename: R L B
authors.initials: RLB
authors.lastname: Ramos
authors.affiliation: The Rockefeller University, 1230 York Avenue 10021, New York, NY, USA.|Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Prof. Paulo de Góes, Laboratório de Biologia Molecular de Bactérias, Centro de Ciěncias da Saúde, Bloco I, Cidade Universitária, Rio de Janeiro, RJ 21941.590, Brazil.
authors.forename: L A
authors.initials: LA
authors.lastname: Teixeira
authors.affiliation: Instituto de Puericultura Martagão Gesteira, Universidade Federal do Rio de Janeiro.|Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Prof. Paulo de Góes, Laboratório de Biologia Molecular de Bactérias, Centro de Ciěncias da Saúde, Bloco I, Cidade Universitária, Rio de Janeiro, RJ 21941.590, Brazil.
authors.forename: L R
authors.initials: LR
authors.lastname: Ormonde
authors.affiliation: Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Prof. Paulo de Góes, Laboratório de Biologia Molecular de Bactérias, Centro de Ciěncias da Saúde, Bloco I, Cidade Universitária, Rio de Janeiro, RJ 21941.590, Brazil.
authors.forename: P L A
authors.initials: PLA
authors.lastname: Siqueira
authors.affiliation: Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Brazil.
authors.forename: M S
authors.initials: MS
authors.lastname: Santos
authors.affiliation: Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Brazil.
authors.forename: D
authors.initials: D
authors.lastname: Marangoni
authors.affiliation: The Rockefeller University, 1230 York Avenue 10021, New York, NY, USA.|Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Prof. Paulo de Góes, Laboratório de Biologia Molecular de Bactérias, Centro de Ciěncias da Saúde, Bloco I, Cidade Universitária, Rio de Janeiro, RJ 21941.590, Brazil.
authors.forename: A M S
authors.initials: AMS
authors.lastname: Figueiredo
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001938:Brazil; D003428:Cross Infection / Q000382:microbiology; D004269:DNA, Bacterial / Q000032:analysis; D004196:Disease Outbreaks; D004352:Drug Resistance, Microbial / Q000235:genetics*; D018432:Drug Resistance, Multiple; D006801:Humans; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D016712:Mupirocin / Q000494:pharmacology*; D020161:Physical Chromosome Mapping; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D016712:Mupirocin