Inhaled nitric oxide in a patient with severe pulmonary embolism.
We describe a 66-year-old woman with right-sided heart failure and cardiogenic shock resulting from severe pulmonary embolism. Her hemodynamic status improved dramatically with the use of inhaled nitric oxide. A proposed mechanism of action and a review of the literature are presented.
Schenk
P
P
Intensive Care Unit, Department of Internal Medicine 4, Department of Internal Medicine, University of Vienna, Vienna, Austria. Peter.Schenk@akh-wien.ac.at
Mittermayer
C
C
Ratheiser
K
K
D000280:Administration, Inhalation; D000368:Aged; D004359:Drug Therapy, Combination; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D009569:Nitric Oxide / Q000627:therapeutic use*; D011655:Pulmonary Embolism / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D012770:Shock, Cardiogenic / Q000209:etiology; D013997:Time Factors; D014662:Vasoconstrictor Agents / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use*; D020246:Venous Thrombosis / Q000150:complications
D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents; D009569:Nitric Oxide; D004837:Epinephrine