Fatal case due to methicillin-resistant Staphylococcus aureus small colony variants in an AIDS patient.
We describe the first known case of a fatal infection with small colony variants of methicillin-resistant Staphylococcus aureus in a patient with AIDS. Recovered from three blood cultures as well as from a deep hip abscess, these variants may have resulted from long-term antimicrobial therapy with trimethoprim/sulfamethoxazole for prophylaxis of Pneumocystis carinii pneumonia.
Seifert
H
H
University of Cologne, Germany. harald.seifert@uni-koeln.de
von Eiff
C
C
Fätkenheuer
G
G
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy* / Q000382:microbiology; D000038:Abscess / Q000188:drug therapy / Q000382:microbiology; D000328:Adult; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology; D017809:Fatal Outcome; D006615:Hip; D006801:Humans; D008297:Male; D016106:Methicillin Resistance; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology; D011110:Polymorphism, Genetic; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics* / Q000254:growth & development