Insulin increases in vitro production of Th2 profile cytokines in peripheral blood cultures in subjects at high risk of diabetes type 1 and patients with newly diagnosed IDDM.
Kretowski
A
A
Department of Endocrinology, Medical Academy, Bialystok, Poland. akretows@amb.ac.bialystok.pl
Myśliwiec
J
J
Szelachowska
M
M
Kinalski
M
M
Kinalska
I
I
D000293:Adolescent; D000328:Adult; D002478:Cells, Cultured; D016207:Cytokines / Q000096:biosynthesis*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D005260:Female; D006801:Humans; D007328:Insulin / Q000494:pharmacology*; D007371:Interferon-gamma / Q000096:biosynthesis; D016753:Interleukin-10 / Q000096:biosynthesis; D015847:Interleukin-4 / Q000096:biosynthesis; D008297:Male; D009536:Niacinamide / Q000494:pharmacology; D010835:Phytohemagglutinins / Q000494:pharmacology; D006377:T-Lymphocytes, Helper-Inducer / Q000187:drug effects* / Q000378:metabolism*
D016207:Cytokines; D007328:Insulin; D010835:Phytohemagglutinins; D016753:Interleukin-10; D015847:Interleukin-4; D009536:Niacinamide; D007371:Interferon-gamma