[Treatment of postoperative recurrence of digestive cancers: peritonitis carcinomatosa].
Carcinomatous peritonitis is the most frequent type of recurrence observed after surgery for cancer of the digestive tract. Most patients with carcinomatous peritonitis present with bowel obstruction and/or ascites. Surgical treatment including colostomy and intestinal anastomosis and chemotherapy have been attempted in patients with carcinomatous peritonitis, although the results have not been satisfactory. New drug delivery systems, such as mitomycin C-adsorbed charcoal, anticancer drugs entrapped in microspheres, and immunoconjugates composed of anticancer drugs and antibodies, will be powerful new tools for the treatment of metastatic cancer.
Yamaguchi
T
T
First Department of Surgery, Kyoto Prefectural University of Medicine, Japan.
Takahashi
T
T
Sawai
K
K
Hagiwara
A
A
Taniguchi
H
H
Kitamura
K
K
Otsuji
E
E
Sakakura
C
C
Shirasu
M
M
Okamoto
K
K
Yamagishi
H
H
D004067:Digestive System Neoplasms / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology; D010534:Peritoneal Neoplasms / Q000556:secondary* / Q000628:therapy; D010538:Peritonitis / Q000209:etiology* / Q000628:therapy