Hypertrophic discoid lupus erythematosus of the conjunctiva.
OBJECTIVE
To report the ophthalmic manifestations of hypertrophic discoid lupus erythematosus of the conjunctiva.


METHODS
Case report and review of biopsy results.


RESULTS
A 58-year-old woman with a history of chronic blepharoconjunctivitis presented with an unusual raised conjunctival lesion. Previous biopsy slides were reviewed and interpreted as diagnostic of discoid lupus erythematosus, hypertrophic or verrucous type. Both blepharoconjunctivitis and the raised conjunctival lesion resolved with hydroxychloroquine therapy.


CONCLUSIONS
A raised conjunctival mass in the context of refractory blepharoconjunctivitis should elicit suspicion for discoid lupus erythematosus. The hypertrophic variant of this disease can affect the conjunctiva.
Uy
H S
HS
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.
Pineda
R
R
Shore
J W
JW
Polcharoen
W
W
Jakobiec
F A
FA
Foster
C S
CS
D001706:Biopsy; D001762:Blepharitis / Q000175:diagnosis* / Q000188:drug therapy; D002908:Chronic Disease; D003228:Conjunctiva / Q000473:pathology*; D003231:Conjunctivitis / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D006984:Hypertrophy; D008179:Lupus Erythematosus, Discoid / Q000175:diagnosis* / Q000188:drug therapy; D008875:Middle Aged
D006886:Hydroxychloroquine