title: Repetitive abortion in Neospora-infected ewes.
abstract: Pregnant ewes inoculated with cultured Neospora caninum tachyzoites in 1995, 1996, or 1995 and 1996 aborted or delivered weak or clinically normal lambs in 1996. Nine of 11 ewes in the study had previously produced infected lambs or fetuses after being experimentally infected in 1995. Fetuses and lambs produced in 1996 showed histologic lesions and zoites indicative of Neospora. Serologic responses and production of infected fetuses/lambs indicated systemic neosporosis in the ewes during gestation, although tachyzoites could not be cultured from maternal tissues. The repetitive infection of fetuses, and resulting clinical and histopathologic findings in the present study are similar to those reported in naturally infected cattle, adding to the already established similarities of neosporosis between sheep and cattle.
authors.affiliation: Department of Veterinary Sciences, University of Wyoming, Laramie 82070, USA.
authors.forename: W R
authors.initials: WR
authors.lastname: Jolley
authors.forename: M M
authors.initials: MM
authors.lastname: McAllister
authors.forename: A M
authors.initials: AM
authors.lastname: McGuire
authors.forename: R A
authors.initials: RA
authors.lastname: Wills
mesh_terms: D000026:Abortion, Habitual / Q000469:parasitology / Q000662:veterinary*; D000034:Abortion, Veterinary / Q000469:parasitology* / Q000503:physiopathology; D000818:Animals; D000831:Animals, Newborn; D000913:Antibodies, Protozoan / Q000097:blood; D001921:Brain / Q000196:embryology / Q000469:parasitology; D002522:Chlorocebus aethiops; D003048:Coccidiosis / Q000150:complications / Q000635:transmission / Q000662:veterinary*; D005260:Female; D005333:Fetus / Q000469:parasitology / Q000473:pathology; D019084:Fluorescent Antibody Technique, Indirect / Q000662:veterinary; D006321:Heart / Q000469:parasitology; D018445:Infectious Disease Transmission, Vertical / Q000662:veterinary; D018688:Neospora / Q000502:physiology*; D011247:Pregnancy; D012756:Sheep; D012757:Sheep Diseases / Q000469:parasitology* / Q000635:transmission; D014709:Vero Cells
chemical_list: D000913:Antibodies, Protozoan