title: [Incidence of treatment modalities for cancer of the small intestine in Burgundy (France)].
abstract: OBJECTIVE
  To determine the epidemiological characteristics and management of cancers of the small bowel, on a population-based survey.
  
  
  METHODS
  The registry of digestive tumors of Burgundy recorded all new cases of cancers of the small intestine in the departments of Côte d'Or and Saône et Loire (1,052,000 inhabitants).
  
  
  RESULTS
  Two hundred and ten new cases of malignant tumors of the small intestine were recorded between 1976 and 1995 including 4 main histological types: adenocarcinomas (39.5%), carcinoids (26.2%), lymphomas (18.6%) and sarcomas (10.5%). Age-standardized incidence rates for males and females were respectively 8.8 and 5.6 per 1,000,000 inhabitants. There was evidence of lymph node invasion in 29.5% and visceral metastasis in 31.4%. Treatment was primarily surgical (90.5%), with a post-operative death rate of 17.1%. The rate of curative surgery remained constant over time, averaging 58.6%, 20% of the patients underwent chemotherapy, with a high proportion of lymphomas, often in association with surgery. The relative survival rates at 1, 3 and 5 years were 51.2, 38.3 and 32.7%, respectively. The multivariate analysis showed that survival was linked to age, and strongly to histological type and stage of diagnosis.
  
  
  CONCLUSIONS
  Cancers of the small intestine are an heterogeneous group of rare tumors, often diagnosed at advanced stage. No significant improvement has been achieved in their management over the past 20 years.
authors.affiliation: Registre Bourguignon des Cancers Digestifs (INSERM CRI 9505 et équipe associée INSERM-DGS), Faculté de Médecine, Dijon.
authors.forename: R
authors.initials: R
authors.lastname: Barraya
authors.forename: A M
authors.initials: AM
authors.lastname: Benhamiche
authors.forename: E
authors.initials: E
authors.lastname: Rassiat
authors.forename: J M
authors.initials: JM
authors.lastname: Phelip
authors.forename: J L
authors.initials: JL
authors.lastname: Jouve
authors.forename: J
authors.initials: J
authors.lastname: Faivre
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D007414:Intestinal Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012042:Registries; D015996:Survival Rate