title: [Carotid atherosclerotic lesions in stroke patients with diabetes mellitus].
abstract: The aim of the study was to assess the incidence of atherosclerotic lesions on carotid arteries among diabetic subjects suffering from cerebrovascular accident. A further aim was to investigate the relationship between the severity of the carotid lesion, the stroke subtype and the fatal outcome. One hundred and sixty eight patients treated because of cerebrovascular accident at the Dept. of Neurology University Medical School of Debrecen were studied. The age of the patients, the duration of diabetes and hypertension were registrated. Base on duplex scanning carotid lesions were divided in 6 groups of severity (normal, intimal sclerosis, slight, moderately severe, severe stenosis and occlusion). Based on clinical signs and CT results stroke subtypes were divided into five groups (lacunar and non-lacunar infarctions, hemorrhages, normal CT and others). The relationship between severity of carotid lesions, stroke subtype and lethal outcome was assessed using statistical tests. Carotid stenosis of different severity was detected in 60% of the cases. Severity of stenosis was independent from duration of diabetes, but it was positively related to duration of hypertension (p = 0.016). In 1/3 of the patients lacunar strokes, in another 1/3 non-lacunar strokes were observed. No significant relationship was found between severity of carotid stenosis, stroke subtype and lethal outcome of the patients (p = 0.53 and p = 0.26 respectively). Diabetic patients suffering from stroke have a higher incidence of carotid artery atherosclerotic lesions than diabetics without stroke. A special attention should be paid to the carotid duplex sonography in order to detect diabetic cerebral macroangiopathies in early, asymptomatic stage.
authors.affiliation: Debreceni Orvostudományi Egyetem Neurológiai Klinika.
authors.forename: B
authors.initials: B
authors.lastname: Fülesdi
authors.forename: D
authors.initials: D
authors.lastname: Bereczki
authors.forename: L
authors.initials: L
authors.lastname: Mihálka
authors.forename: I
authors.initials: I
authors.lastname: Fekete
authors.forename: P
authors.initials: P
authors.lastname: Síró
authors.forename: Z
authors.initials: Z
authors.lastname: Leányvári
authors.forename: A
authors.initials: A
authors.lastname: Valikovics
authors.forename: L
authors.initials: L
authors.lastname: Csiba
mesh_terms: D000368:Aged; D016893:Carotid Stenosis / Q000175:diagnosis* / Q000453:epidemiology; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D003925:Diabetic Angiopathies / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D008297:Male; D014057:Tomography, X-Ray Computed; D018616:Ultrasonography, Doppler, Duplex