[Survival and prognostic factors of germ cell tumors of the testis in the departments of Bas-Rhin, Isère, and Somme].
The authors report a study of the prognosis of germ cell tumours of the testis in populations of the Bas-Rhin, Isère and Some departments. This study was performed on French Eurocare data (European testicular cancer register study). 247 patients diagnosed between 1987 and 1993 were studied. Estèv's method and model were used to estimate the relative survival and for prognosis analysis with reference to the French age-matched male population. 84.6% of patients were between the ages of 20 and 49 years. The 5-years relative survival was 90.1%; 95 CI% [85.5-94.8]. The 5-year relative survival was lower (63.9%) in advanced forms (stage III). Univariate analysis in 223 patients demonstrated the following significant prognostic factors: stage, metastatic sites, treatment, retroperitoneal lymph node dissection and testicular vascular invasion. Multivariate analysis identified: stage, age, CNS metastases, retroperitoneal lymph node dissection and treatment. This study confirms the generally good prognosis of this cancer. As reported in the literature, factors negatively influencing relative survival are those related to advanced disease. Age, a controversial factor in the literature, was correlated with relative survival in this study.
Rahmani
Z
Z
Laboratoire d'épidémiologie et de santé publique, Faculté de Médecine, Strasbourg.
Hédelin
G
G
Ménégoz
F
F
Raverdy
N
N
D000328:Adult; D000367:Age Factors; D000368:Aged; D005602:France; D018237:Germinoma / Q000473:pathology*; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012042:Registries; D016019:Survival Analysis; D013736:Testicular Neoplasms / Q000473:pathology*