H1 antihistamines, cytochrome P450 and multidrug resistance: is there a link?
Rihoux
J P
JP
UCB Pharma SA, Research and Development, Chemin du Foriest, Braine-l'Alleud, Belgium. Jean-Pierre.Rihoux@UCB-Group.com
Nicolas
J M
JM
D001711:Biotransformation; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D018432:Drug Resistance, Multiple; D006634:Histamine H1 Antagonists / Q000378:metabolism* / Q000493:pharmacokinetics; D006801:Humans; D006899:Mixed Function Oxygenases / Q000378:metabolism*
D006634:Histamine H1 Antagonists; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A