title: [Hemodynamic evaluation and clinical outcome of children with severe dilated cardiomyopathy eligible for heart transplantation].
abstract: OBJECTIVE
  To evaluate hemodynamic parameters and clinical outcome of children with severe cardiomyopathy who are candidates for heart transplantation.
  
  
  METHODS
  Twenty four children aged from 4 months to 10 years and 8 months (mean 3.7 +/- 2.5 years) from February 1992 to May 1996, were submitted to hemodynamic study and the following parameters were measured: cardiac output, mean pulmonary artery pressure (MPAP) and capillary wedge pressure. The pulmonary vascular resistance index (PVRI) and transpulmonary pressure gradient (TGP) were calculated.
  
  
  RESULTS
  Ten (41.6%) children were transplanted (group A), 5 (20.8%) are still waiting heart transplantation (group B) and 9 (37.6%) died (group C). The mean age of the B and C group were significantly different. The PVRI, MPAP and TPG were significant lower in group A than group C (p = 0.01; p = 0.044 and p = 0.023 respectively).
  
  
  CONCLUSIONS
  The profile of the hemodynamic parameters of children with severe dilated cardiomyopathy was compatible with the clinical findings. The age was the only difference comparing groups B and C. PVRI, MPAP and TPG were significant factors between group A and C. The older the patient, the worse was the prognosis.
authors.affiliation: Instituto do Coração do Hospital das Clínicas, FMUSP.
authors.forename: E
authors.initials: E
authors.lastname: Azeka
authors.forename: M B
authors.initials: MB
authors.lastname: Marcial
authors.forename: P R
authors.initials: PR
authors.lastname: Camargo
authors.forename: L
authors.initials: L
authors.lastname: Kajita
authors.forename: A C
authors.initials: AC
authors.lastname: Aliman
authors.forename: J O
authors.initials: JO
authors.lastname: Auler
authors.forename: E
authors.initials: E
authors.lastname: Atik
authors.forename: M
authors.initials: M
authors.lastname: Ebaid
mesh_terms: D000367:Age Factors; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D016027:Heart Transplantation / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007223:Infant