Leptin, polycystic ovaries and polycystic ovary syndrome.
As soon as leptin was discovered four years ago, its potential as a player in the polycystic ovary syndrome (PCOS) was explored in a primitive way, though little light was shed on the enigma that is PCOS. As a second wave of leptin research is now available, we review how the expanded role of the cytokine in reproduction might yet impact upon our understanding of PCOS.
Jacobs
H S
HS
Department of Endocrinology, UCL Medical School, The Middlesex Hospital, London.
Conway
G S
GS
D005260:Female; D006801:Humans; D007328:Insulin / Q000378:metabolism / Q000502:physiology*; D007333:Insulin Resistance / Q000502:physiology; D020738:Leptin; D008297:Male; D009478:Neuropeptide Y / Q000378:metabolism / Q000502:physiology; D009765:Obesity / Q000503:physiopathology; D010053:Ovary / Q000503:physiopathology*; D011085:Polycystic Ovary Syndrome / Q000503:physiopathology*; D011506:Proteins / Q000378:metabolism / Q000502:physiology*
D007328:Insulin; D020738:Leptin; D009478:Neuropeptide Y; D011506:Proteins