Bacteria-related sequences in a simian cytomegalovirus-derived stealth virus culture.
Extensive sequencing of cloned DNA isolated from the culture of an African green monkey simian cytomegalovirus-derived stealth virus has identified multiple regions of highly significant homology to various bacterial genes. The apparent acquisition of bacterial sequences extends the potential role of stealth viruses as natural vectors in the transfer of genetic information. The findings highlight the dynamic interface between viral and bacterial genomes and the potential of this interaction in the emergence and spread of novel pathogens. The term viteria is proposed for microorganisms that contain both eukaryotic-viral and prokaryotic-bacterial genetic sequences.
Martin
W J
WJ
Center for Complex Infectious Diseases, Rosemead, California 91770, USA.
D000818:Animals; D001419:Bacteria / Q000235:genetics*; D002460:Cell Line; D002522:Chlorocebus aethiops; D003587:Cytomegalovirus / Q000235:genetics* / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000821:virology; D015673:Fatigue Syndrome, Chronic / Q000821:virology; D005822:Genetic Vectors; D006801:Humans; D011995:Recombination, Genetic; D012689:Sequence Homology, Nucleic Acid