title: Mutation in the HNF-4alpha gene affects insulin secretion and triglyceride metabolism.
authors.affiliation: Department of Endocrinology, Dalby Primary Health Center, University of Lund, Sweden. markku.lehto@endo.mas.lu.se
authors.forename: M
authors.initials: M
authors.lastname: Lehto
authors.forename: P O
authors.initials: PO
authors.lastname: Bitzén
authors.forename: B
authors.initials: B
authors.lastname: Isomaa
authors.forename: C
authors.initials: C
authors.lastname: Wipemo
authors.forename: Y
authors.initials: Y
authors.lastname: Wessman
authors.forename: C
authors.initials: C
authors.lastname: Forsblom
authors.forename: T
authors.initials: T
authors.lastname: Tuomi
authors.forename: M R
authors.initials: MR
authors.lastname: Taskinen
authors.forename: L
authors.initials: L
authors.lastname: Groop
mesh_terms: D000368:Aged; D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; D004268:DNA-Binding Proteins; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000235:genetics* / Q000378:metabolism*; D005260:Female; D051557:Hepatocyte Nuclear Factor 4; D006801:Humans; D007328:Insulin / Q000172:deficiency / Q000378:metabolism*; D000078790:Insulin Secretion; D008297:Male; D008875:Middle Aged; D009154:Mutation / Q000235:genetics / Q000502:physiology*; D010750:Phosphoproteins / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*; D014280:Triglycerides / Q000097:blood*
chemical_list: D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; D004268:DNA-Binding Proteins; C496592:HNF4A protein, human; D051557:Hepatocyte Nuclear Factor 4; D007328:Insulin; C403128:MLX protein, human; D010750:Phosphoproteins; D014157:Transcription Factors; D014280:Triglycerides