title: Intraductal papillary carcinoma of the parotid gland with low malignancy.
abstract: A peculiar case of papillary carcinoma arising in the parotid gland is reported. A 68-year-old woman presented with a right, painless, parotid mass, measuring approximately 3 cm in greatest diameter. A conservative parotidectomy was performed. Histologically, the neoplasm showed exophytic papillary projections into a cavity. The cells were focally suggestive of epidermoidal differentiation, whereas a transitional differentiation was noted in other portions, as in bladder papilloma. Immunohistochemical studies showed strong positivity of the neoplastic cells for cytokeratin and weak positivity for PCNA and Mib-1. We classified this neoplasm among the papillary tumors with a low-grade of malignancy.
authors.affiliation: Department of Experimental Medicine and Pathology, La Sapienza University, Rome, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Caramanico
authors.forename: P
authors.initials: P
authors.lastname: Marcone
authors.forename: P
authors.initials: P
authors.lastname: Rovere
authors.forename: C
authors.initials: C
authors.lastname: Della Rocca
mesh_terms: D000368:Aged; D034961:Antigens, Nuclear; D002291:Carcinoma, Papillary / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism; D019394:Ki-67 Antigen; D009687:Nuclear Proteins / Q000378:metabolism; D010307:Parotid Neoplasms / Q000378:metabolism / Q000473:pathology*; D018809:Proliferating Cell Nuclear Antigen / Q000378:metabolism
chemical_list: D034961:Antigens, Nuclear; D019394:Ki-67 Antigen; D009687:Nuclear Proteins; D018809:Proliferating Cell Nuclear Antigen; D007633:Keratins