title: Combined surgical and medical approach to intravenous leiomyomatosis with cardiac extension.
abstract: Intravenous leiomyomatosis with cardiac extension is a rare entity. The case of a 49-year-old patient is described: she was operated on for intracaval intra-atrial leiomyomatosis. After an incomplete procedure (the tumour appeared not totally resectable), the patient was treated for a period of three years with a GnRH-analogue, whereafter the patient was doing clinically well and the tumour, although it regained some growth, was in a stable situation. This new strategy seems of certain importance to the surgeon, as it carries an alternative to a high-risk reoperation. To our knowledge, this is the first description of such a combined therapeutical approach.
authors.affiliation: Department of Cardiothoracic Surgery, St Antonius Hospital, Nieuwegein, The Netherlands.
authors.forename: J A
authors.initials: JA
authors.lastname: Hameleers
authors.forename: C J
authors.initials: CJ
authors.lastname: Zeebregts
authors.forename: R P
authors.initials: RP
authors.lastname: Hamerlijnck
authors.forename: J R
authors.initials: JR
authors.lastname: Elbers
authors.forename: T M
authors.initials: TM
authors.lastname: Hameeteman
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D017273:Goserelin / Q000627:therapeutic use; D006325:Heart Atria / Q000473:pathology; D006338:Heart Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D006801:Humans; D018231:Leiomyomatosis / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D008875:Middle Aged; D019043:Vascular Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D017273:Goserelin