[Initial estimation effect of body mass on survival of patients with endometrial carcinoma].
OBJECTIVE
It has long been known that the risk of some cancers, including endometrial, are associated with obesity. A question that remains is whether over-weight is associated with significant difference in survival rate between patients with different body mass index (BMI).


METHODS
During the period 1984-1996 121 patients with endometrial carcinoma have been evaluated retrospectively in the Department of Gynecology & Obstetrics in Hospital of Słupsk.


RESULTS
The middle age of women with endometrial carcinoma was 60.2 years, the youngest has been 38 years old and the oldest--86 years. In the city lived 74.4% women and in the village 25.6%. The percentage of nulliparas was 11.6%, in women group with 1-2 parity 42.1% and when they had more than 2 parity 46.3%. The middle age of nulliparas was lower than multiparas (59.4 vs 63.6 years). In our material endomeriosis was found in association with endometrial carcinoma in 12 (9.9%) of 121 cases. In two cases of endometriosis carcinoma developed. Of 121 patients with endometrial carcinoma 22.3% had over-weight; 9.9% hypertension; 0.8% diabetes mellitus, 28.1% over-weight and hypertension, 2.5% over-weight and diabetes mellitus, 0.8% hypertension and diabetes mellitus, 7.4% over-weight with hypertension and diabetes mellitus. 28.1% patients hadn't these diseases. There was statistically significant difference in survival rate between patients with BMI (p = 0.02). On the whole, five-year-survival was observed in 73.0% of women. Five-year-survival patients with BMI (25-29) was 86.8%; with BMI (30-34) was 74.1%; with BMI (> 34) was 67.4%. The patients with BMI (20-24) five-year-survival was lowest 67.4% and the same as in patients with highest obesity [BMI (> 34)].


CONCLUSIONS
Endometrial carcinoma patients with BMI (25-29), were found to have better survival rate than patients with other BMI. There wasn't effect of hypertension and diabetes mellitus on of survival rate of patients with endometrial carcinoma (p = 0.25 and p = 0.26). The study was limited by the confinent and bias of a retrospective analysis, but this finding was statistically significant (p = 0.02).
Studziński
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Oddziału Połozniczo-Ginekologicznego Samodzielnego Publicznego Szpitala Zespolonego w Słupsku.
Branicka
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000401:mortality*; D002391:Catchment Area, Health; D016889:Endometrial Neoplasms / Q000150:complications / Q000401:mortality*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D011044:Poland / Q000453:epidemiology; D012189:Retrospective Studies; D015996:Survival Rate