Characteristics of frequency-of-seeing curves for a motion stimulus in glaucoma eyes, glaucoma suspect eyes, and normal eyes.
This study compared frequency-of-seeing curves for a line displacement test in glaucoma patients and normals. Probit analysis of the frequency-of-seeing curves provided the motion thresholds and the slopes of the frequency-of-seeing curves, represented by the interquartile range. The thresholds and interquartile ranges were significantly elevated in the glaucoma eyes and suspect eyes, compared to controls. A logistic regression model incorporating both the interquartile range and threshold significantly improved the sensitivity of the motion test in the suspects. Abnormal shallowing of the slope of the motion frequency-of-seeing curve may represent one of the earliest changes in glaucoma.
Westcott
M C
MC
Institute of Ophthalmology, Department of Visual Science, London, UK.
Fitzke
F W
FW
Crabb
D P
DP
Hitchings
R A
RA
D000328:Adult; D000368:Aged; D005902:Glaucoma, Open-Angle / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D009039:Motion Perception / Q000502:physiology*; D011594:Psychometrics; D012372:ROC Curve; D012684:Sensory Thresholds / Q000502:physiology