title: [Spread of hepatitis C and separate genotypes of hepatitis C virus in a region with a moderately active epidemic process].
abstract: The prevalence of hepatitis C virus (HCV) is studied in different age and risk groups in the city of Vladimir and the genotypes of the virus circulating at this territory are determined. Anti-HCV are detected in 2.4% donors and 1.4% pregnant women. Population immunity to HCV gradually increases with age. AntiHCV are detected in 0.9% children aged 3-6 years, in 1.8% in the group aged 20-29 years, and in 2.9% in the group aged 30-39 years. Medical workers, mental inpatients, hematological patients, patients hospitalized at hemoperfusion departments, and imprisoned subjects were referred to groups at risk of HCV infection: antiHCV were detected in 3.9, 5.4, 13.8, 53.6, and 24.5% of these groups, respectively. Genotype 1b predominates in the structure of HCV genotypes circulating in Vladimir: 72.9% in all examined population groups. In addition to this genotype, genotypes 2a, 2b, and 3a were detected (2.9, 2.9, and 15.7%, respectively). Genotype 3a was the most incident in children aged 0-14 years.
authors.forename: S N
authors.initials: SN
authors.lastname: Kuzin
authors.forename: E V
authors.initials: EV
authors.lastname: Lisitsina
authors.forename: E I
authors.initials: EI
authors.lastname: Samokhvalov
authors.forename: I V
authors.initials: IV
authors.lastname: Shakhgil'dian
authors.forename: L E
authors.initials: LE
authors.lastname: Kuzina
authors.forename: T N
authors.initials: TN
authors.lastname: Manina
authors.forename: E A
authors.initials: EA
authors.lastname: Lisitsin
authors.forename: D K
authors.initials: DK
authors.lastname: L'vov
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D005260:Female; D005838:Genotype; D016174:Hepacivirus / Q000235:genetics* / Q000276:immunology; D006526:Hepatitis C / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D011247:Pregnancy; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology
chemical_list: D000914:Antibodies, Viral