[The metabolic effects of the neurotropic action of actovegin during hypoxia].
Recent data on the mechanisms of the effect of aktovegin on the brain in hypoxia are systematized. It is shown that the drug improves the transport and utilization of oxygen and glucose, activates the aerobic routes of energy metabolism and, as a result, improves the functional state of the central nervous system cells.
Boiarinov
G A
GA
Department of Anesthesiology and the Science of Resuscitation and Transfusion, Military Medical Institute, Nizhni Novgorod, Russia.
Penkovich
A A
AA
Mukhina
I V
IV
D000332:Aerobiosis / Q000187:drug effects; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D000697:Central Nervous System Stimulants / Q000494:pharmacology / Q000627:therapeutic use*; D004734:Energy Metabolism / Q000187:drug effects; D006418:Heme / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D000860:Hypoxia / Q000188:drug therapy / Q000378:metabolism*
D000697:Central Nervous System Stimulants; D006418:Heme; C015646:Actovegin