title: Mega-mergers in the pharmaceutical industry. In whose interests?
abstract: Companies merge to achieve economies of scale. In an industry such as the pharmaceutical industry which relies on a high level of investment in research and development, such mergers appear rational. However, it is not at all obvious that a higher level of investment by a smaller number of firms will necessarily lead to an increased rate of genuine innovations. There is a risk that conflicts of interest and the pursuit of short term gains may encourage more mergers than is optimal for the industry. The impact of mega-mergers in the pharmaceutical industry on research output, employees, shareholders, financial advisers, managers and patients is discussed. A healthy pharmaceutical industry, able to invest the necessary resources in the development of innovative medicines is in the interest of patients and shareholders alike. Over-concentration may interfere with innovative activity and lead to monopolistic power. Close scrutiny of merger activity is important but in a deregulated world, governments may have little power to act. In any case, a drug-specific monopolistic industry may be beneficial to some countries which may therefore be reluctant to act in the interest of the world as a single community in search of more effective medicines.
authors.affiliation: Centre for Evidence-Based Pharmacotherapy, University of Nottingham, England. Pazlwp@pan1.pharm.nottingham.ac.uk
authors.forename: A L
authors.initials: AL
authors.lastname: Po
mesh_terms: D016527:Drug Costs; D004345:Drug Industry / Q000191:economics*; D017850:Economics, Pharmaceutical; D005060:Europe; D005102:Health Expenditures; D006801:Humans; D007564:Japan; D010361:Patients; D004364:Pharmaceutical Preparations / Q000191:economics*; D012106:Research / Q000191:economics*; D006113:United Kingdom; D014481:United States
chemical_list: D004364:Pharmaceutical Preparations