title: Effects of four antigenic fractions of Pasteurella multocida serotype A on phagocytosis of chicken peripheral blood leukocytes.
abstract: The effects of four antigenic fractions of Pasteurella multocida serotype A isolated from a duck in the Philippines on the phagocytic activity of chicken peripheral blood leukocytes were studied by a flow cytometer. These fractions were the lipopolysaccharide-protein complex (LPS), crude capsular antigen (CCA), ribosomal fraction (RS) and outer cell layer (OCL). Among these four antigens, only CCA but not LPS RS and OCL, significantly increased the phagocytic activities of mononuclear cells (MNC) and polymorphonuclear cells (PMN). This result indicates that CCA has an immunological property enhancing the phagocytic activities of MNC and PMN.
authors.affiliation: National Institute of Animal Health, Ibaraki, Japan.
authors.forename: F S
authors.initials: FS
authors.lastname: Maslog
authors.forename: M
authors.initials: M
authors.lastname: Motobu
authors.forename: N
authors.initials: N
authors.lastname: Hayashida
authors.forename: K
authors.initials: K
authors.lastname: Yoshihara
authors.forename: T
authors.initials: T
authors.lastname: Morozumi
authors.forename: M
authors.initials: M
authors.lastname: Matsumura
authors.forename: Y
authors.initials: Y
authors.lastname: Hirota
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000494:pharmacology*; D002478:Cells, Cultured; D002645:Chickens / Q000276:immunology*; D004372:Ducks; D005434:Flow Cytometry; D007962:Leukocytes / Q000187:drug effects / Q000276:immunology*; D016979:Pasteurella multocida / Q000276:immunology*; D010587:Phagocytosis / Q000187:drug effects*
chemical_list: D000942:Antigens, Bacterial