title: Mediastinal tumors of peripheral nervous system origin.
abstract: A wide spectrum of benign and malignant tumors of peripheral nervous system origin can arise in the mediastinum. These neoplasms are more frequent in the posterior mediastinum and can develop from peripheral nerves, sympathetic and parasympathetic ganglia, and neural tube embryonic remnants. The clinicopathologic features of mediastinal schwannomas, melanotic schwannomas, neurofibromas, ganglioneuromas, granular cell tumors, malignant tumors of peripheral nerve sheath origin, malignant melanocytic tumors of peripheral nerve sheath origin, neuroblastomas, ganglioneuroblastomas, and pigmented neuroectodermal tumors of infancy are reviewed.
authors.affiliation: Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Marchevsky
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000378:metabolism; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005729:Ganglioneuroma / Q000175:diagnosis / Q000378:metabolism / Q000401:mortality / Q000473:pathology; D016586:Granular Cell Tumor / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000401:mortality / Q000473:pathology*; D009442:Neurilemmoma / Q000175:diagnosis / Q000378:metabolism / Q000401:mortality / Q000473:pathology; D009455:Neurofibroma / Q000175:diagnosis / Q000378:metabolism / Q000401:mortality / Q000473:pathology; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000401:mortality / Q000473:pathology*; D011379:Prognosis; D015996:Survival Rate
chemical_list: D014408:Biomarkers, Tumor