Thin-layer cytology meets viral hybrid capture.
This commentary addresses the benefits of liquid-based thin-layer cervical cytology, and the applicability of residual samples for human papilloma virus assay. The potential for use of this technology in wide-scale screening as well as the many unanswered issues, in particular cost-benefit ratio and financing, are also discussed.
Leiman
G
G
Cytopathology Unit, School of Pathology, South African Institute for Medical Research, Johannesburg, South Africa.
D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005260:Female; D016591:Histocytological Preparation Techniques; D006801:Humans; D027383:Papillomaviridae / Q000302:isolation & purification*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014626:Vaginal Smears / Q000191:economics / Q000379:methods* / Q000639:trends; D002578:Uterine Cervical Dysplasia / Q000473:pathology*