title: Vascular suppression technique in MRI using Gd-DTPA: improving image quality of MR myelography.
abstract: OBJECTIVE
  To delete signals of juxta-thecal venous structures on MR myelograms, we evaluated the potential of Gd-DTPA as a negative contrast material in experiments and actual MR myelograms.
  
  
  METHODS
  We measured the signals of Gd-DTPA solutions of various concentrations on T2-weighted turbo-SE and turbo-STIR images. The experiments revealed that 0.83 mmol/L Gd-DTPA worked as a negative contrast material in turbo-STIR. Subsequently, we obtained turbo-STIR myelograms of 31 patients who complained of lumbago or sciatica before and after intravenous administration of 0.15 mmol/kg Gd-DTPA, which was presumed to provide the optimal plasma density in vivo.
  
  
  RESULTS
  On postcontrast MR myelograms, the venous signals around the thecal sac decreased remarkably in almost all the cases as compared with precontrast images. In these cases, the nerve roots could be observed clearly.
  
  
  CONCLUSIONS
  Gd-DTPA can work as a negative contrast material in turbo-STIR sequences. This characteristic should be used to improve the image quality of MR myelography using turbo-STIR.
authors.affiliation: Department of Radiology, Kamitsuga General Hospital, Kanuma City, Tochigi Prefecture, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Nasu
authors.forename: H
authors.initials: H
authors.lastname: Takano
authors.forename: H
authors.initials: H
authors.lastname: Ito
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007403:Intervertebral Disc / Q000473:pathology*; D008159:Lumbar Vertebrae / Q000033:anatomy & histology / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011786:Quality Control; D013116:Spinal Cord / Q000033:anatomy & histology* / Q000098:blood supply
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA