title: Locally focused contrast-enhanced carotid MRA.
abstract: With conventional Fourier transform (FT) magnetic resonance imaging (MRI), it is difficult to perform contrast-enhanced three-dimensional (3D) MR angiography (MRA) with the temporal and spatial resolution necessary to depict the carotid arteries. However, locally focused (LF) MRI is a more efficient method that utilizes prior knowledge of the image content to reconstruct images from sparse k-space samples. In this paper, we show how LF MRI can be used to perform high-resolution gadolinium (Gd)-enhanced 3D carotid MRA in less than 10 seconds. First, the accuracy of the technique was demonstrated by comparing LF and conventional (FT) images of a vascular phantom. Then the method was used to perform Gd-enhanced 3D MRA of a patient's carotid arteries. Instead of using bolus timing, the arterial phase was retrospectively identified in a consecutive series of images, just as in X-ray angiography.
authors.affiliation: Department of Radiology, University of Chicago, Illinois 60637, USA.
authors.forename: V Y
authors.initials: VY
authors.lastname: Kuperman
authors.forename: S K
authors.initials: SK
authors.lastname: Nagle
authors.forename: M T
authors.initials: MT
authors.lastname: Alley
authors.forename: G H
authors.initials: GH
authors.lastname: Glover
authors.forename: D N
authors.initials: DN
authors.lastname: Levin
mesh_terms: D000328:Adult; D002339:Carotid Arteries / Q000473:pathology*; D003287:Contrast Media; D005583:Fourier Analysis; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007275:Injections, Intravenous; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D019047:Phantoms, Imaging; D013997:Time Factors
chemical_list: D003287:Contrast Media; C064925:gadodiamide; D019786:Gadolinium DTPA