[Spread of hepatitis C and separate genotypes of hepatitis C virus in a region with a moderately active epidemic process].
The prevalence of hepatitis C virus (HCV) is studied in different age and risk groups in the city of Vladimir and the genotypes of the virus circulating at this territory are determined. Anti-HCV are detected in 2.4% donors and 1.4% pregnant women. Population immunity to HCV gradually increases with age. AntiHCV are detected in 0.9% children aged 3-6 years, in 1.8% in the group aged 20-29 years, and in 2.9% in the group aged 30-39 years. Medical workers, mental inpatients, hematological patients, patients hospitalized at hemoperfusion departments, and imprisoned subjects were referred to groups at risk of HCV infection: antiHCV were detected in 3.9, 5.4, 13.8, 53.6, and 24.5% of these groups, respectively. Genotype 1b predominates in the structure of HCV genotypes circulating in Vladimir: 72.9% in all examined population groups. In addition to this genotype, genotypes 2a, 2b, and 3a were detected (2.9, 2.9, and 15.7%, respectively). Genotype 3a was the most incident in children aged 0-14 years.
Kuzin
S N
SN
Lisitsina
E V
EV
Samokhvalov
E I
EI
Shakhgil'dian
I V
IV
Kuzina
L E
LE
Manina
T N
TN
Lisitsin
E A
EA
L'vov
D K
DK
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D005260:Female; D005838:Genotype; D016174:Hepacivirus / Q000235:genetics* / Q000276:immunology; D006526:Hepatitis C / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D011247:Pregnancy; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology
D000914:Antibodies, Viral