title: Economic benefits of prophylaxis with diclazuril against subclinical coccidiosis in lambs reared indoors.
abstract: One hundred and twenty weaned male lambs, naturally infected with Eimeria species, were used to assess the economic benefits of the prophylactic administration of diclazuril. They were randomly divided into four groups of 30 lambs on the basis of their bodyweight and output of oocysts. The groups were either left untreated (group 1), treated orally with a simple dose of diclazuril at 1 mg/kg (group 2), with two doses two weeks apart (group 3), or with sulphadimethoxine at 50 mg/kg for five consecutive days (group 4). No clinical signs of coccidiosis were observed in any of the groups. The output of oocysts was significantly reduced on day 7 after treatment in group 2, on days 7, 14 and 28 in group 3 and on days 7 and 14 in group 4. No significant differences were found between the treated and untreated groups for bodyweight, carcase weight and carcase classification. The mean fattening period was shorter for the treated lambs (52 and 55 days) than for the untreated controls (60 days). The average growth rate of the lambs treated twice with diclazuril and with sulphadimethoxine was improved and the feed conversion rates of the lambs treated once or twice with diclazuril were 7 per cent and 16 per cent better than that of the untreated lambs.
authors.affiliation: Veterinary Clinic Les Althéas Pamiers, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Alzieu
authors.forename: C
authors.initials: C
authors.lastname: Mage
authors.forename: L
authors.initials: L
authors.lastname: Maes
authors.forename: C
authors.initials: C
authors.lastname: de Mûelenaere
mesh_terms: D000822:Animal Husbandry / Q000191:economics; D000818:Animals; D001835:Body Weight; D003048:Coccidiosis / Q000188:drug therapy / Q000191:economics / Q000662:veterinary*; D003049:Coccidiostats / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*; D006128:Growth; D008297:Male; D009570:Nitriles / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*; D010270:Parasite Egg Count; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000191:economics / Q000469:parasitology; D014227:Triazines / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*
chemical_list: D003049:Coccidiostats; D009570:Nitriles; D014227:Triazines; C057884:diclazuril