Duplication, multiduplication, and amplification of genes encoding drug-metabolizing enzymes: evolutionary, toxicological, and clinical pharmacological aspects.
Ingelman-Sundberg
M
M
Division of Molecular Toxicology, Karolinska Institute, Stockholm, Sweden.
D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics* / Q000378:metabolism; D019143:Evolution, Molecular; D005784:Gene Amplification; D020440:Gene Duplication; D005982:Glutathione Transferase / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010601:Pharmacology, Clinical; D010641:Phenotype
D019389:Cytochrome P-450 CYP2D6; D005982:Glutathione Transferase; D004364:Pharmaceutical Preparations