PKS1, a substrate phosphorylated by phytochrome that modulates light signaling in Arabidopsis.
Plants constantly monitor their light environment in order to grow and develop optimally, in part through use of the phytochromes, which sense red/far-red light. A phytochrome binding protein, PKS1 (phytochrome kinase substrate 1), was identified that is a substrate for light-regulated phytochrome kinase activity in vitro. In vivo experiments suggest that PKS1 is phosphorylated in a phytochrome-dependent manner and negatively regulates phytochrome signaling. The data suggest that phytochromes signal by serine-threonine phosphorylation.
Fankhauser
C
C
Plant Biology Laboratory, Howard Hughes Medical Institute, Salk Institute, La Jolla, CA 92037, USA.
Yeh
K C
KC
Lagarias
J C
JC
Zhang
H
H
Elich
T D
TD
Chory
J
J
D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism*; D029681:Arabidopsis Proteins; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D017343:Genes, Plant; D000071677:Histidine Kinase; D047908:Intracellular Signaling Peptides and Proteins; D008027:Light; D008565:Membrane Proteins; D008969:Molecular Sequence Data; D009154:Mutation; D010750:Phosphoproteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D010766:Phosphorylation; D010786:Photoreceptor Cells; D010834:Phytochrome / Q000378:metabolism*; D051942:Phytochrome A; D051939:Phytochrome B; D010940:Plant Proteins; D011494:Protein Kinases / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D015398:Signal Transduction; D014157:Transcription Factors
D029681:Arabidopsis Proteins; D002352:Carrier Proteins; D047908:Intracellular Signaling Peptides and Proteins; D008565:Membrane Proteins; C497973:PHYA protein, Arabidopsis; C497952:PHYB protein, Arabidopsis; C485609:PKS1 protein, Arabidopsis; C119522:PKS1 protein, plant; D010750:Phosphoproteins; D051942:Phytochrome A; D010940:Plant Proteins; D011993:Recombinant Fusion Proteins; D014157:Transcription Factors; D010834:Phytochrome; D051939:Phytochrome B; D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases; D000071677:Histidine Kinase