[Bath-PUVA therapy of granuloma annulare].
Sixteen patients with generalized granuloma anulare and two patients with localized granuloma anulare received bath-PUVA therapy. Their lesions previously had not responded to conventional therapy. After an average of 55 (11 to 61) treatments and a mean cumulative dose of 69.5 (7.1 to 261.5) J/cm2, complete remission was observed in 5 patients and a clear improvement in 10 patients. Three patients stopped therapy after few treatments. Recurrent lesions appeared in 4 patients; in three of them reinitiation of the bath-PUVA-therapy again led to complete remission. Maintenance therapy for several months may be useful for patients suffering from relapsing granuloma anulare. Potential risks of long-lasting bath-PUVA therapy should be taken into consideration.
Salomon
N
N
Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Universität, München.
Walchner
M
M
Messer
G
G
Plewig
G
G
Röcken
M
M
D001494:Baths; D016460:Granuloma Annulare / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy; D012008:Recurrence; D012074:Remission Induction; D016896:Treatment Outcome