The effect of the aqueous extract of Cynomorium coccineum on the epididymal sperm pattern of the rat.
An aqueous extract of Cynomorium coccineum was administered by stomach tube to ten mature male Wistar rats, at a dose of 47 mg/100 kg body weight/day for 14 consecutive days. Ten rats were kept as controls and received normal saline by oral route at the same dosing interval. Sperm was collected from the epididymes after decapitation. The results revealed that the water extract of the Cynomorium coccineum induced significant increase in the sperm count, improved the percentage of live sperm and their motility and decreased the number of abnormal sperm. Testicular histology showed increased spermatogenesis and seminiferous tubules full of sperm in the treated group compared with the controls.
Abd el-Rahman
H A
HA
Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, King Saud University, Saudi Arabia.
el-Badry
A A
AA
Mahmoud
O M
OM
Harraz
F A
FA
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D004822:Epididymis / Q000166:cytology / Q000187:drug effects*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D012669:Seminal Vesicles / Q000166:cytology / Q000187:drug effects; D013076:Sperm Count / Q000187:drug effects*; D013081:Sperm Motility / Q000187:drug effects*
D010936:Plant Extracts