title: Forming and inhibiting PRT active sites.
authors.forename: J L
authors.initials: JL
authors.lastname: Smith
mesh_terms: D000582:Amidophosphoribosyltransferase / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism; D000818:Animals; D001665:Binding Sites; D002384:Catalysis; D011756:Diphosphates / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000378:metabolism; D004926:Escherichia coli / Q000201:enzymology; D006801:Humans; D006860:Hydrogen Bonding; D007041:Hypoxanthine Phosphoribosyltransferase / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism; D008670:Metals / Q000378:metabolism; D008958:Models, Molecular; D010754:Phosphoribosyl Pyrophosphate / Q000378:metabolism; D011487:Protein Conformation; D011687:Purines / Q000378:metabolism; D014345:Trypanosoma / Q000201:enzymology
chemical_list: D011756:Diphosphates; D004791:Enzyme Inhibitors; D008670:Metals; D011687:Purines; D010754:Phosphoribosyl Pyrophosphate; D000582:Amidophosphoribosyltransferase; D007041:Hypoxanthine Phosphoribosyltransferase