Insulin resistance.
It is thought that a number of interrelated variables, all involved in insulin resistance, may play a role in the pathophysiology of coronary artery disease. These include dyslipidemia, dysglycemia and hyperinsulinemia. Insulin resistance, the insulin resistance syndrome and atherogenesis are all thought to involve endothelial dysfunction, though in different vascular beds.
Leiter
L
L
University of Toronto, St Michael's Hospital, Toronto, Canada. leiter@smh.toronto.on.ca
D001161:Arteriosclerosis / Q000097:blood / Q000209:etiology; D003327:Coronary Disease / Q000097:blood / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D006943:Hyperglycemia / Q000150:complications*; D006946:Hyperinsulinism / Q000150:complications; D006949:Hyperlipidemias / Q000150:complications*; D007333:Insulin Resistance; D012307:Risk Factors