Mapping of the alpha-1,6-fucosyltransferase gene, FUT8, to human chromosome 14q24.3.
Alpha-1,6-Fucosyltransferase (alpha1,6FucT) is involved in the biosynthesis of asparagine-linked glycoprotein oligosaccharides. In this study, we isolated a genomic clone for the human alpha1,6FucT gene (FUT8) and mapped it by fluorescence in situ hybridization to chromosome 14q24.3. This study suggests a distinct localization of FUT8 from genes for other human fucosyltransferases reported to date.
Yamaguchi
Y
Y
Department of Biochemistry, Osaka University Medical School, Osaka, Japan.
Fujii
J
J
Inoue
S
S
Uozumi
N
N
Yanagidani
S
S
Ikeda
Y
Y
Egashira
M
M
Miyoshi
O
O
Niikawa
N
N
Taniguchi
N
N
D002874:Chromosome Mapping; D002883:Chromosomes, Human, Pair 14 / Q000235:genetics*; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics; D005091:Exons; D005647:Fucosyltransferases / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008969:Molecular Sequence Data; D015183:Restriction Mapping
D018076:DNA, Complementary; D005647:Fucosyltransferases; C031692:galactoside 3-fucosyltransferase; C020559:Glycoprotein 6-alpha-L-fucosyltransferase