title: Lactonamycin, a new antimicrobial antibiotic produced by Streptomyces rishiriensis MJ773-88K4. II. Structure determination.
abstract: The absolute structure of a new antibiotic lactonamycin is described. The NMR studies deduced one of four possible structures for the aglycon attached by a rhodinose through glycosidic bond. The stereochemistry of the sugar obtained by an acid hydrolysis was determined to be L-form by measuring optical rotation. The stereochemistry of the aglycon was determined by X-ray crystallographic analysis.
authors.affiliation: Institute of Microbial Chemistry, Tokyo, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Matsumoto
authors.forename: T
authors.initials: T
authors.lastname: Tsuchida
authors.forename: H
authors.initials: H
authors.lastname: Nakamura
authors.forename: R
authors.initials: R
authors.lastname: Sawa
authors.forename: Y
authors.initials: Y
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Naganawa
authors.forename: H
authors.initials: H
authors.lastname: Iinuma
authors.forename: T
authors.initials: T
authors.lastname: Sawa
authors.forename: T
authors.initials: T
authors.lastname: Takeuchi
authors.forename: M
authors.initials: M
authors.lastname: Shiro
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006868:Hydrolysis; D007211:Indoles / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009285:Naphthoquinones / Q000737:chemistry; D009904:Optical Rotation; D016339:Spectrometry, Mass, Fast Atom Bombardment
chemical_list: D000900:Anti-Bacterial Agents; D007211:Indoles; D009285:Naphthoquinones; C102442:lactonamycin