Oxybutynin enhances the metabolism of clomipramine and dextrorphan possibly by induction of a cytochrome P450 isoenzyme.
Grözinger
M
M
Härtter
S
S
Hiemke
C
C
Röschke
J
J
D000368:Aged; D018680:Cholinergic Antagonists / Q000494:pharmacology*; D002997:Clomipramine / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis*; D003917:Dextrorphan / Q000378:metabolism*; D004347:Drug Interactions; D004790:Enzyme Induction; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000096:biosynthesis*; D008333:Mandelic Acids / Q000494:pharmacology*
D018680:Cholinergic Antagonists; D007527:Isoenzymes; D008333:Mandelic Acids; D003917:Dextrorphan; D003577:Cytochrome P-450 Enzyme System; C005419:oxybutynin; D002997:Clomipramine