title: Immunity in experimental murine filariasis: roles of T and B cells revisited.
abstract: We have reevaluated the contributions of T and B cells in Brugia malayi infection by utilizing knockout mice on a uniform background (C57BL/6J). We find that B-cell-deficient mice are more permissive to infection than T-cell-deficient mice.
authors.affiliation: University of Connecticut Health Center, Farmington, Connecticut, USA.
authors.forename: S
authors.initials: S
authors.lastname: Babu
authors.forename: L D
authors.initials: LD
authors.lastname: Shultz
authors.forename: T R
authors.initials: TR
authors.lastname: Klei
authors.forename: T V
authors.initials: TV
authors.lastname: Rajan
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D017178:Brugia malayi / Q000276:immunology*; D004195:Disease Models, Animal; D005368:Filariasis / Q000276:immunology*; D007109:Immunity; D051379:Mice; D008810:Mice, Inbred C57BL; D013601:T-Lymphocytes / Q000276:immunology*