Prothrombin G20210A mutation in a child with spinal cord infarction.
Prothrombin G20210A is a newly described common mutation that is associated with an increased risk of arterial and venous thrombosis. We describe a healthy child heterozygous for this prothrombin mutation who had a spinal cord infarct with no other prothrombotic risk factors.
Young
G
G
Departments of Hematology/Oncology and Neurology, Children's National Medical Center, George Washington University, Washington, DC., USA.
Krohn
K A
KA
Packer
R J
RJ
D005190:Family; D005260:Female; D006579:Heterozygote; D006801:Humans; D007223:Infant; D007238:Infarction / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D009154:Mutation; D011516:Prothrombin / Q000235:genetics*; D012307:Risk Factors; D013116:Spinal Cord / Q000098:blood supply*; D019851:Thrombophilia / Q000235:genetics
D011516:Prothrombin