Epidemiology of hypertriglyceridemia and cardiovascular disease.
Epidemiologic studies provide increasing evidence that hypertriglyceridemia is a risk factor for cardiovascular disease. A meta-analysis of 17 population-based studies of triglyceride levels and cardiovascular disease identified a 76% increase in cardiovascular disease risk in women and a 31% increase in men associated with a 1 mmol/L increase in triglyceride levels. Additional epidemiologic studies have shown that plasma triglyceride levels and low-density lipoprotein particle size predict subsequent coronary artery disease. Taken together, the existing epidemiologic data may help identify a group of patients who may benefit from interventions aimed at decreasing triglyceride levels associated with an increased risk of cardiovascular disease.
Austin
M A
MA
School of Public Health and Community Medicine, University of Washington, Seattle 98195, USA.
D005260:Female; D006801:Humans; D006953:Hyperlipoproteinemia Type IV / Q000145:classification; D015228:Hypertriglyceridemia / Q000150:complications* / Q000453:epidemiology; D015994:Incidence; D008297:Male; D017202:Myocardial Ischemia / Q000097:blood / Q000209:etiology* / Q000401:mortality; D012307:Risk Factors