Merkel cell carcinoma: an aggressive neoplasm.
This article presents a rare case of Merkel cell carcinoma (MCC) of the skin. This tumor is also known as trabecular carcinoma or cutaneous small cell undifferentiated carcinoma (CSCUC). This patient had a palpable non-tender mass in her right upper thigh and a large palpable lymph node in the right inguinal area. Microscopic examination revealed Merkel cell carcinoma (MCC) in the skin of the upper thigh as well as in the inguinal lymph node. Immunoperoxidase stains confirmed the diagnosis. Due to its aggressiveness and very unfavorable prognosis, prompt diagnosis and adequate treatment are essential. Wide local excision with adequate margins followed by radiation therapy is the treatment of choice.
Datta
C K
CK
United Hospital Center, Clarksburg, USA.
Mendoza
C B
CB
D000368:Aged; D015266:Carcinoma, Merkel Cell / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D011379:Prognosis; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery