title: Pain affect without pain sensation in a patient with a postcentral lesion.
abstract: We report findings from clinical examination and cutaneous laser stimulation in a 57-year-old male, who suffered from a right-sided postcentral stroke. In this patient, we were able to demonstrate (i) a dissociation of discriminative and affective components of pain perception and, for the first time in humans, (ii) the dependence of sensory-discriminative pain component and first pain sensation on the integrity of the lateral pain system.
authors.affiliation: Department of Neurology, University of Duesseldorf, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Ploner
authors.forename: H J
authors.initials: HJ
authors.lastname: Freund
authors.forename: A
authors.initials: A
authors.lastname: Schnitzler
mesh_terms: D000339:Affect / Q000502:physiology*; D002545:Brain Ischemia / Q000175:diagnosis / Q000503:physiopathology*; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000503:physiopathology; D006358:Hot Temperature; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000503:physiopathology* / Q000523:psychology*; D017288:Pain Threshold / Q000502:physiology; D010812:Physical Stimulation; D012677:Sensation / Q000502:physiology*; D013003:Somatosensory Cortex / Q000098:blood supply*