title: Management and treatment of patients with acromegaly.
abstract: Untreated acromegaly causes substantial morbidity and mortality, and results in a marked reduction in quality of life. For this reason, the treatment goals need to be well defined and therapy optimised. This article describes the clinical approach to acromegaly, including: Pathophysiology of growth hormone secretion; Clinical features; Biochemical and radiological diagnosis; Treatment goals and therapeutic options; Prognosis.
authors.affiliation: Centre for Neuroendocrinology, Royal Free Hospital, London.
authors.forename: P
authors.initials: P
authors.lastname: Coskeran
mesh_terms: D000172:Acromegaly / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D000328:Adult; D013006:Growth Hormone / Q000502:physiology; D006801:Humans; D008297:Male; D011379:Prognosis
chemical_list: D013006:Growth Hormone