title: Dienyl diketones as anticancer agents: synthesis and biological evaluation of some aromatic derivatives.
abstract: Aiming to develop anticancer agents, synthesis and in vitro evaluation of aromatic dienyl diketone derivatives were carried out. All the aromatic (Z.E)-dienyl diketones synthesized exhibit strong in vitro inhibition of tumor cell growth against Colon cell line.
authors.affiliation: Department of Pharmacy, Tajen Junior College of Pharmacy, Ping-Tung, Taiwan.
authors.forename: P C
authors.initials: PC
authors.lastname: Shieh
authors.forename: C W
authors.initials: CW
authors.lastname: Ong
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D003110:Colonic Neoplasms / Q000188:drug therapy; D006367:HeLa Cells; D006801:Humans; D007659:Ketones / Q000138:chemical synthesis* / Q000494:pharmacology*; D007700:Kinetics; D008956:Models, Chemical; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D007659:Ketones