title: [Gammagraphy of somatostatin receptors in an ACTH secreting thymic carcinoid].
abstract: Ectopic ACTH secretion represent 10 to 15% in the causes of Cushing's syndrome. Carcinoid tumor of the thymus is a rare neoplasm and is currently believed to arise from population of thymic cells of neural crest origin. We present the case of a 43-year-old man with a corticotropin hormone (ACTH) secreting thymus carcinoid. 111In-octreotide scintigraphy demonstrated an intense uptaken on the lesion. The surgical specimen measured 17 x 18 x 18 cm and weighed 1. 25 kg. Postoperatively the patient was treated by chemotherapy and radiotherapy. A follow-up 111In-octreotide scintigraphy was normal. Very few scintigraphic images of these lesions have been published in the literature. Somatostatin receptor scintigraphy can be successful in the detection and follow-up of ACTH-secreting neuroendocrine tumors.
authors.affiliation: Servicio de Medicina Nuclear, HCU "Lozano Blesa", Zaragoza, 50009, España.
authors.forename: J
authors.initials: J
authors.lastname: Banzo
authors.forename: P
authors.initials: P
authors.lastname: Razola
authors.forename: E
authors.initials: E
authors.lastname: Prats
authors.forename: E
authors.initials: E
authors.lastname: Freile
authors.forename: J L
authors.initials: JL
authors.lastname: Benito
authors.forename: F
authors.initials: F
authors.lastname: García López
authors.forename: J
authors.initials: J
authors.lastname: García Tirado
authors.forename: M D
authors.initials: MD
authors.lastname: Abós
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000328:Adult; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000601:surgery; D005500:Follow-Up Studies; D006729:Hormones, Ectopic / Q000378:metabolism*; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D015282:Octreotide; D013902:Radiography, Thoracic; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin; D013934:Thymectomy; D013953:Thymus Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D006729:Hormones, Ectopic; D007205:Indium Radioisotopes; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin; D000324:Adrenocorticotropic Hormone; D015282:Octreotide