title: Production of recombinant blood factors in transgenic plants.
abstract: The production of recombinant proteins for therapeutic use in transgenic plants has become an alternative to the isolation of these molecules from natural or other recombinant sources. Plant bioreactors offer the possibility of an inexpensive large scale production of high volumes of recombinant proteins with increased safety concerning contaminations with human pathogens. Several laboratories are involved in the commercial production of the first recombinant products, such as antibodies or recombinant human hemoglobin, from transgenic plants.
authors.affiliation: Meristem Therapeutics, Clermont-Ferrand, France. mtheisen@meristem-therapeutics.com
authors.forename: M
authors.initials: M
authors.lastname: Theisen
mesh_terms: D001798:Blood Proteins / Q000096:biosynthesis* / Q000235:genetics; D018506:Gene Expression Regulation, Plant; D006801:Humans; D030821:Plants, Genetically Modified / Q000378:metabolism*; D011994:Recombinant Proteins / Q000096:biosynthesis
chemical_list: D001798:Blood Proteins; D011994:Recombinant Proteins