Dienyl diketones as anticancer agents: synthesis and biological evaluation of some aromatic derivatives.
Aiming to develop anticancer agents, synthesis and in vitro evaluation of aromatic dienyl diketone derivatives were carried out. All the aromatic (Z.E)-dienyl diketones synthesized exhibit strong in vitro inhibition of tumor cell growth against Colon cell line.
Shieh
P C
PC
Department of Pharmacy, Tajen Junior College of Pharmacy, Ping-Tung, Taiwan.
Ong
C W
CW
D000970:Antineoplastic Agents / Q000494:pharmacology*; D003110:Colonic Neoplasms / Q000188:drug therapy; D006367:HeLa Cells; D006801:Humans; D007659:Ketones / Q000138:chemical synthesis* / Q000494:pharmacology*; D007700:Kinetics; D008956:Models, Chemical; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D007659:Ketones