title: Hydroxyurea-induced acute interstitial pneumonitis in a patient with essential thrombocythemia.
abstract: Hydroxyurea is a drug widely used to control myeloproliferative disorders, due in part to its relative lack of severe side effects. We present a case of acute interstitial pneumonitis in a patient who was treated with hydroxyurea for essential thrombocythemia. The clinical course suggests that the interstitial pneumonitis was induced by hydroxyurea. This is the first case of hydroxyurea-induced acute interstitial pneumonitis reported in the literature.
authors.affiliation: Department of Hematology, Hospital Xeral de Galicia, Complexo Hospitalario Universitario de Santiago de Compostela, La Coruña, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Quintás-Cardama
authors.forename: M
authors.initials: M
authors.lastname: Pérez-Encinas
authors.forename: S
authors.initials: S
authors.lastname: Gonzalez
authors.forename: A
authors.initials: A
authors.lastname: Bendaña
authors.forename: J L
authors.initials: JL
authors.lastname: Bello
mesh_terms: D006801:Humans; D006918:Hydroxyurea / Q000009:adverse effects* / Q000627:therapeutic use; D017563:Lung Diseases, Interstitial / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D013920:Thrombocythemia, Essential / Q000150:complications* / Q000188:drug therapy
chemical_list: D006918:Hydroxyurea