title: Genetic variation at six STR loci (HUMTH01, HUMTPOX, HUMCSF1PO, HUMF13A01, HUMFES/FPS, HUMVWFA31) in Aragon (north Spain).
abstract: The STR loci HUMTH01, HUMPTPOX, HUMCSF1PO, HUMF13A01, HUMFES/FPS and HUMVWFA31 are widely used in forensic casework analyses and population data are necessary to estimate the frequency of a DNA profile. This paper presents the results of a survey aimed to investigate the allele frequency distribution of these loci in an important Spanish population (Aragon, North Spain). Statistical analysis to determine whether allele frequencies were in Hardy-Weinberg Equilibrium was carried out and also to obtain some parameters of medico-legal interest. There was no evidence of association between the alleles of the loci. The Aragonese sample does not differ substantially from other Caucasian populations.
authors.affiliation: Department of Legal Medicine, University of Zaragoza, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Martinez Jarreta
authors.forename: P
authors.initials: P
authors.lastname: Diaz Roche
authors.forename: E
authors.initials: E
authors.lastname: Abecia
mesh_terms: D003625:Data Collection; D003627:Data Interpretation, Statistical; D016002:Discriminant Analysis; D005554:Forensic Medicine / Q000379:methods*; D005787:Gene Frequency / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics*; D005838:Genotype; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D015203:Reproducibility of Results; D017422:Sequence Analysis, DNA / Q000379:methods*; D013030:Spain; D044465:White People / Q000235:genetics*