title: [Hydatidiform mole. A case of hydrothorax, expression of a non-neoplastic complication].
abstract: Marked stimulation of the chorionic gonadotropins underlies the frequent finding in the mole of larger ovaries with multiple luteal cysts, identifiable using ultrasound imaging, resembling ovarian hyperstimulation syndrome. The authors report a case of hyadatid pregnancy which presented serious non-neoplastic complications. Laboratory tests showed high values of beta-hCG and GOT/GPT, electrolytic alterations, hypoproteinemia, hypoalbuminemia, associated with conditions of severe dyspnea and tachycardia following hydrothorax diagnosed by X-ray. USG showed hypertrophic placenta containing anechoid lacunar areas and swollen ovaries with multiple luteal cysts. Positive results were achieved by using intensive therapy leading to the restitutio ad integrum of damaged functions. Endocrine hyperactivity of the molar trophoblast, with high levels of beta-hCG was responsible for ovarian hyperstimulation. Important findings for the early diagnosis of hyadatid pregnancy are: beta-hCG assay and ultrasound scan; moreover, an adequate follow-up lasting about 6 months is necessary to evaluate the serial trend of beta-hCG and the disappearance of ovarian luteal cysts.
authors.affiliation: I Istituto di Clinica Ostetrica e Ginecologica, Università degli Studi di Roma, La Sapienza.
authors.forename: P
authors.initials: P
authors.lastname: Mancino
authors.forename: S
authors.initials: S
authors.lastname: Moretti
authors.forename: M
authors.initials: M
authors.lastname: Cocola
authors.forename: E
authors.initials: E
authors.lastname: Greco
authors.forename: A
authors.initials: A
authors.lastname: Bartolacci
authors.forename: R
authors.initials: R
authors.lastname: Russo
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000032:analysis; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000000981:diagnostic imaging*; D006876:Hydrothorax / Q000175:diagnosis* / Q000209:etiology; D010048:Ovarian Cysts / Q000000981:diagnostic imaging*; D016471:Ovarian Hyperstimulation Syndrome / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011248:Pregnancy Complications; D016216:Ultrasonography, Prenatal
chemical_list: D006063:Chorionic Gonadotropin