[Cardiolipin antibodies in pregnancy of high risk].
Cardiolipin IgG and IgM antibodies (CAb) were studied in 116 cases of high-risk pregnancy. All the women were undergoing examination or treatment in regional perinatal center. CAb occurred more frequently in antenatal fetal death (50%). In blood hypertension, habitual abortions, history of infertility, gestational gestosis, CAb were encountered in 21.4, 20, 20 and 15.2% of cases, respectively. Intrauterine growth retardation was associated with CAb in 33.3% of cases. CAb occurred in pregnant women of different groups who had high uterine vascular resistance. The above findings indicate CAb contribution to genesis of gestational complications in high risk pregnancy.
Karpov
N Iu
NIu
Baranov
A A
AA
Shilkina
N P
NP
Nasonov
E L
EL
Aleksandrov
S E
SE
Abaĭtova
N E
NE
Krylov
V L
VL
Lavrinenko
A A
AA
Pushkina
N I
NI
D000293:Adolescent; D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000032:analysis*; D015415:Biomarkers / Q000097:blood; D002308:Cardiolipins / Q000276:immunology; D005260:Female; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D011247:Pregnancy; D011256:Pregnancy Outcome; D018566:Pregnancy, High-Risk / Q000097:blood / Q000276:immunology*; D012189:Retrospective Studies
D017153:Antibodies, Anticardiolipin; D015415:Biomarkers; D002308:Cardiolipins; D007074:Immunoglobulin G; D007075:Immunoglobulin M