Mutation in the HNF-4alpha gene affects insulin secretion and triglyceride metabolism.
Lehto
M
M
Department of Endocrinology, Dalby Primary Health Center, University of Lund, Sweden. markku.lehto@endo.mas.lu.se
Bitzén
P O
PO
Isomaa
B
B
Wipemo
C
C
Wessman
Y
Y
Forsblom
C
C
Tuomi
T
T
Taskinen
M R
MR
Groop
L
L
D000368:Aged; D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; D004268:DNA-Binding Proteins; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000235:genetics* / Q000378:metabolism*; D005260:Female; D051557:Hepatocyte Nuclear Factor 4; D006801:Humans; D007328:Insulin / Q000172:deficiency / Q000378:metabolism*; D000078790:Insulin Secretion; D008297:Male; D008875:Middle Aged; D009154:Mutation / Q000235:genetics / Q000502:physiology*; D010750:Phosphoproteins / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*; D014280:Triglycerides / Q000097:blood*
D051778:Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; D004268:DNA-Binding Proteins; C496592:HNF4A protein, human; D051557:Hepatocyte Nuclear Factor 4; D007328:Insulin; C403128:MLX protein, human; D010750:Phosphoproteins; D014157:Transcription Factors; D014280:Triglycerides