title: A peritrophin-like protein expressed in the embryonic tracheae of Drosophila melanogaster.
abstract: We have cloned and sequenced a cDNA from Drosophila melanogaster that encodes a protein homologous to the peritrophins, a family of chitin-binding proteins from the peritrophic matrix of insects. Unexpectedly, the gene, Gasp, is expressed in the embryonic tracheae. We suggest that this family of proteins may be present in other tissues than the peritrophic matrix, particularly where nutrient or gas exchange are important, and/or where invasion by parasites or viruses is possible. We have also mapped two similar genes that had been sequenced by the Berkeley Drosophila Genome Project, and find that these three very similar genes are not clustered, but are located on three different chromosomes.
authors.affiliation: School of Biological Sciences, University of Nebraska, Lincoln 68588-0118, USA.
authors.forename: M K
authors.initials: MK
authors.lastname: Barry
authors.forename: A A
authors.initials: AA
authors.lastname: Triplett
authors.forename: A C
authors.initials: AC
authors.lastname: Christensen
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D018076:DNA, Complementary; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics*; D015870:Gene Expression; D019476:Insect Proteins / Q000235:genetics*; D008969:Molecular Sequence Data; D017421:Sequence Analysis; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D014132:Trachea / Q000196:embryology
chemical_list: D018076:DNA, Complementary; D029721:Drosophila Proteins; C119878:Gasp protein, Drosophila; D019476:Insect Proteins