title: Development of brightness matching and colour vision deficits in juvenile diabetics.
abstract: We studied hue discrimination and brightness matching throughout the spectrum in ten juvenile patients suffering from diabetes mellitus (Type I) with no (eight patients) or mild (two patients) retinopathy. In addition, the FM 100-Hue test was performed. The data were collected once every year over 5 years. Over the 5 years, the diabetics show a continual change in the shape of their brightness matching function. Wavelength discrimination ability remains quite stable with time at the long end of the spectrum but is variable at short wavelengths. FM-100 error scores remain similar over the period tested, at a level slightly higher than that of a control group. Additional experiments show that the sensitivity of the S-cone in the diabetic group is similar to that of controls. The results can be explained by an early relative reduction in the sensitivity of post-receptoral processes in juvenile diabetics.
authors.affiliation: University Eye Hospital, Department of Neuro-ophthalmology and Pathophysiology of Vision, Tübingen, Germany. anne.kurtenbach@uni-tuebingen.de
authors.forename: A
authors.initials: A
authors.lastname: Kurtenbach
authors.forename: U
authors.initials: U
authors.lastname: Schiefer
authors.forename: A
authors.initials: A
authors.lastname: Neu
authors.forename: E
authors.initials: E
authors.lastname: Zrenner
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D003117:Color Vision Defects / Q000209:etiology*; D015350:Contrast Sensitivity; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000503:physiopathology / Q000523:psychology; D005500:Follow-Up Studies; D006801:Humans; D011601:Psychophysics; D017949:Retinal Cone Photoreceptor Cells / Q000503:physiopathology