title: Early and late outcome after elective cardiac surgery in patients with cirrhosis.
abstract: BACKGROUND
  A prospective study was performed to evaluate the early and late outcome after elective cardiac surgery in patients with cirrhosis.
  
  
  METHODS
  All patients who underwent elective cardiac surgery between 1995 and 1997, and were suspected of having a history of cirrhosis, were followed in the intensive care unit (ICU), during hospitalization and after hospital discharge. All patients received high doses of aprotinin during surgery.
  
  
  RESULTS
  Ten patients of Child-Pugh class A and 2 patients of Child-Pugh class B were studied. All patients had signs of portal hypertension, and 11 of 12 patients had thrombocytopenia. In the first 24 h after operation, the median chest tube output was 810 mL (range 350 to 1,500 mL). Median ICU and hospital stays were 3 and 15 days, respectively (range 2 to 10 and 7 to 36 days, respectively). Seven patients experienced postoperative morbidity and 7 patients had significant complications after their hospital discharge. One death occurred in the ICU. Two deaths occurred after hospital discharge and were related to further hepatic damage.
  
  
  CONCLUSIONS
  These results suggest that, in patients with mild or moderate cirrhosis, the incidence of significant complications was high after elective cardiac surgery, increasing the length of stay in ICU and overall hospitalization time and compromising the health status, even well after the operation.
authors.affiliation: Department of Anesthesiology, Hôpital G. et R. Laënnec, Nantes, France.
authors.forename: P
authors.initials: P
authors.lastname: Bizouarn
authors.forename: A
authors.initials: A
authors.lastname: Ausseur
authors.forename: P
authors.initials: P
authors.lastname: Desseigne
authors.forename: Y
authors.initials: Y
authors.lastname: Le Teurnier
authors.forename: B
authors.initials: B
authors.lastname: Nougarede
authors.forename: M
authors.initials: M
authors.lastname: Train
authors.forename: J L
authors.initials: JL
authors.lastname: Michaud
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures; D017558:Elective Surgical Procedures; D005260:Female; D006331:Heart Diseases / Q000150:complications* / Q000601:surgery; D006801:Humans; D007902:Length of Stay; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013997:Time Factors; D016896:Treatment Outcome