title: Experience with isotonic 2.2% glycine as distension medium for hysteroscopic endomyometrial resection.
abstract: The feasibility of performing hysteroscopic endomyometrial resection using isotonic 2.2% glycine as distension medium was studied in 181 consecutive operations. A standard continuous flow loop-resectoscope was used. Distension was achieved by means of a gravity-fed system and glycine flowed out under its own pressure. The mean (+/-SEM) glycine deficit was 160+/-20 ml and in only 7 patients was it >1 liter (maximum 1,800 ml). Only in patients with >1 liter glycine absorption was there a significant decrease in serum sodium level (mean 9 mmol/l), while serum osmolality remained normal. Apart from 1 case of transient nausea, these patients had no sequelae. We experienced isotonic 2.2% glycine as a useful and safe distending medium for operative hysteroscopy.
authors.affiliation: Department of Obstetrics and Gynecology, Tampere University Hospital, Finland.
authors.forename: A M
authors.initials: AM
authors.lastname: Tapper
authors.forename: P K
authors.initials: PK
authors.lastname: Heinonen
mesh_terms: D000042:Absorption; D000293:Adolescent; D000328:Adult; D001769:Blood; D003613:Danazol / Q000627:therapeutic use; D004717:Endometrium / Q000601:surgery*; D004965:Estrogen Antagonists / Q000627:therapeutic use; D005260:Female; D005998:Glycine / Q000008:administration & dosage* / Q000378:metabolism; D017273:Goserelin / Q000627:therapeutic use; D006801:Humans; D015907:Hysteroscopy; D008875:Middle Aged; D009215:Myometrium / Q000601:surgery*; D009994:Osmolar Concentration; D011372:Progestins / Q000627:therapeutic use; D012996:Solutions; D007507:Therapeutic Irrigation; D013997:Time Factors
chemical_list: D004965:Estrogen Antagonists; D011372:Progestins; D012996:Solutions; D017273:Goserelin; D003613:Danazol; D005998:Glycine