title: [Surgical treatment of pulmonary metastases of osteosarcoma. Apropos of 206 operated cases].
abstract: Two hundred and six patients were operated for lung metastases from osteosarcoma over a period of 7 years. The operative mortality was 0.3%. The actuarial survival for the overall population was 78% at one year. 50% at two years, 40% at three years and 34% at five years. The most significant prognostic factors (p < 0.01) were the number of metastases, the duration of the free interval and the degree of differentiation. Sex, age, site and type of resection of osteosarcoma or the metastases did not have any influence on prognosis. Surgical resection of lung metastases currently constitutes an essential part of the multidisciplinary management of osteosarcoma.
authors.affiliation: Département de Chirurgie, Université de Modène, Italie.
authors.forename: A
authors.initials: A
authors.lastname: Briccoli
authors.forename: S
authors.initials: S
authors.lastname: Ferrari
authors.forename: P
authors.initials: P
authors.lastname: Picci
authors.forename: M
authors.initials: M
authors.lastname: Mercuri
authors.forename: G
authors.initials: G
authors.lastname: Bacci
authors.forename: N
authors.initials: N
authors.lastname: Guernelli
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000401:mortality; D002648:Child; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D012516:Osteosarcoma / Q000401:mortality / Q000556:secondary*; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis; D013997:Time Factors