Fatal herpetic hepatitis in adult following short corticotherapy: a case report.
Herpes simplex virus hepatitis (HSV hepatitis) is an uncommon and severe complication of HSV type 1 and HSV type 2 infection. HSV hepatitis affects mostly immunocompromised patients. We report the case of a young man without any previous known immunodeficiency who developed fatal HSV hepatitis in the first 8 days of oral corticotherapy given for ulcerative colitis. A prompt diagnosis was possible because HSV was recovered from peripheral blood leukocytes.
Seksik
P
P
Medical Intensive Care Unit, Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, France.
Gozlan
J
J
Guitton
C
C
Galula
G
G
Maury
E
E
Offenstadt
G
G
D000208:Acute Disease; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006525:Hepatitis, Viral, Human / Q000175:diagnosis*; D006561:Herpes Simplex / Q000175:diagnosis*; D018259:Herpesvirus 1, Human / Q000302:isolation & purification; D018258:Herpesvirus 2, Human / Q000302:isolation & purification; D006801:Humans; D008297:Male; D011241:Prednisone / Q000627:therapeutic use*
D000893:Anti-Inflammatory Agents; D011241:Prednisone