title: Face immersion in cold water induces prolongation of the QT interval and T-wave changes in children with nonfamilial long QT syndrome.
abstract: We investigated the relation between heart rate and the QT interval using face immersion in cold water in children with long QT syndrome (LQTS) without a family history of this condition, and in control children. The face immersion test revealed that all children with high probability of LQTS had a significantly longer QT interval than control children during face immersion, and that the test could induce T-wave alternans or a notched T-wave in all children with a high probability of LQTS.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Kagoshima University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Yoshinaga
authors.forename: J
authors.initials: J
authors.lastname: Kamimura
authors.forename: T
authors.initials: T
authors.lastname: Fukushige
authors.forename: R
authors.initials: R
authors.lastname: Kusubae
authors.forename: A
authors.initials: A
authors.lastname: Shimago
authors.forename: J
authors.initials: J
authors.lastname: Nishi
authors.forename: Y
authors.initials: Y
authors.lastname: Kono
authors.forename: Y
authors.initials: Y
authors.lastname: Nomura
authors.forename: K
authors.initials: K
authors.lastname: Miyata
mesh_terms: D000293:Adolescent; D002648:Child; D003080:Cold Temperature; D005145:Face; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology*; D006339:Heart Rate; D006801:Humans; D007101:Immersion / Q000009:adverse effects*; D008133:Long QT Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D008297:Male; D015701:Near Drowning / Q000503:physiopathology; D011237:Predictive Value of Tests; D013550:Swimming; D014867:Water
chemical_list: D014867:Water