[The effect of aqueous extracts of hepatotropic medicinal plants on free-radical oxidation processes].
The authors studied the effect of decoctions and infusions of medicinal plants (common barberry, sandy immortelle, common maize, spotted milk thistle) on free-radical oxidation (FRO) in model systems in vitro and in experiments in vivo on nonbred albino mice. In various model systems (in which active forms of oxygen are generated and lipid peroxidation takes place) the plants under study suppressed as well as intensified the processes of lipid peroxidation, depending on the concentration of the phytopreparation and the type of the model systems. In in vivo experiments the drugs of plant origin suppressed lipid peroxidation, reducing the parameters induced by iron and chemoluminescence and the malonic dialdehyde level in the liver.
Ryzhikova
M A
MA
Department of Immunology and Immunopharmacology, All-Russian Center of Eye and Plastic Surgery, Ufa, Russia.
Farkhutdinov
R R
RR
Sibiriak
S V
SV
Zagidullin
Sh Z
ShZ
D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D005609:Free Radicals / Q000378:metabolism; D066298:In Vitro Techniques; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008163:Luminescent Measurements; D008297:Male; D051379:Mice; D010084:Oxidation-Reduction / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D012996:Solutions
D005609:Free Radicals; D010936:Plant Extracts; D012996:Solutions