title: Use of vibrational angioplasty for the treatment of chronic total coronary occlusions: preliminary results.
abstract: The aim of the study was to investigate the feasibility and clinical safety of vibrational angioplasty in the treatment of chronic total coronary occlusions and evaluate the clinical and angiographic factors that are predictive of the procedural success and complications of the procedure. Seventy-eight patients with chronic total occlusions (>3 months) resistant to conventional techniques were treated by vibrational angioplasty using a variety of conventional guidewires. Lesions were successfully crossed in 67 (85.9%) cases and antegrade flow was achieved in 59 (75.5%). Major complications (myocardial infarction and tamponade) occurred in two (2.5%) patients, but no fatalities ensued. Angiographically detectable dissections were seen in 23 (29.5%) patients but only resulted in vessel compromise and reclosure in 5 cases. Multiple stepwise logistic regression analysis identified the duration (<6 months, P = 0.008) and the length of the occlusion (<15 mm, P = 0.03) as independent predictors of final success and the age of the patient (<55 years, P = 0.006) as the only independent predictor of procedural complications. Vibrational angioplasty is a safe technique useful in the treatment of chronic coronary occlusive disease. Patients in whom the procedure is likely to prove most successful may be easily identified by clinical and angiographic features (duration and length of occlusion).
authors.affiliation: Department of Cardiology, University Hospital of Ioannina, Greece.
authors.forename: L K
authors.initials: LK
authors.lastname: Michalis
authors.forename: M R
authors.initials: MR
authors.lastname: Rees
authors.forename: J A
authors.initials: JA
authors.lastname: Davis
authors.forename: E C
authors.initials: EC
authors.lastname: Pappa
authors.forename: K K
authors.initials: KK
authors.lastname: Naka
authors.forename: S
authors.initials: S
authors.lastname: Rokkas
authors.forename: N
authors.initials: N
authors.lastname: Agrios
authors.forename: S
authors.initials: S
authors.lastname: Loukas
authors.forename: J
authors.initials: J
authors.lastname: Goudevenos
authors.forename: D A
authors.initials: DA
authors.lastname: Sideris
mesh_terms: D000328:Adult; D000368:Aged; D017130:Angioplasty / Q000379:methods*; D015906:Angioplasty, Balloon, Coronary; D006328:Cardiac Catheterization / Q000379:methods*; D002908:Chronic Disease; D003327:Coronary Disease / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D016896:Treatment Outcome; D014732:Vibration