title: Evidence for de novo biosynthesis of the polyketide fragment of diaulusterol A by the northeastern pacific dorid nudibranch diaulula sandiegensis
abstract: Stable isotope incorporation experiments using sodium [1, 2-13C2]acetate have demonstrated that the 3-hydroxybutyrate substituent of diaulusterol A (1) is biosynthesized de novo by the dorid nudibranch Diaulula sandiegensis. There was no evidence for acetate incorporation into the steroid portion of 1, nor were radiolabeled mevalonate or cholesterol incorporated.
authors.affiliation: Departments of Chemistry and Oceanography-Earth and Ocean Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z1, Canada.
authors.initials: J
authors.lastname: Kubanek
authors.initials: RJ
authors.lastname: Andersen