The cytotoxicity of methylglyoxal and 3-deoxyglucosone is decreased in the aldehyde reductase gene-transfected cells.
Suzuki
K
K
Department of Biochemistry, Osaka University Medical School, Suita, Japan.
Koh
Y H
YH
Taniguchi
N
N
D000449:Aldehyde Reductase / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D003847:Deoxyglucose / Q000031:analogs & derivatives* / Q000378:metabolism / Q000633:toxicity; D005434:Flow Cytometry; D015870:Gene Expression; D005947:Glucose / Q000378:metabolism / Q000494:pharmacology; D007424:Intracellular Fluid; D016716:PC12 Cells; D011765:Pyruvaldehyde / Q000633:toxicity*; D051381:Rats; D017382:Reactive Oxygen Species; D014162:Transfection
D017382:Reactive Oxygen Species; D011765:Pyruvaldehyde; D003847:Deoxyglucose; D000449:Aldehyde Reductase; C016350:3-deoxyglucosone; D005947:Glucose