[Hyalinizing trabecular adenoma of the thyroid].
Hyalinizing trabecular adenoma (HTA) is a follicle-derived tumor of the thyroid gland that has been described recently. The differential diagnosis includes medullar carcinoma, papillary carcinoma, and paraganglioma of the thyroid. We report a case of thyroid HTA in a 25-year-old woman. The tumor appeared as a <<cold nodule>> of the left thyroid in radionuclide scans. Histologically, the tumor showed tumor cells arranged in trabeculae and a prominent hyaline stroma. The neoplastic cells were focally immunoreactive for thyroglobulin and negative for calcitonin, chromogranin, and S-100 protein. Three years after hemithyroidectomy, the patient is alive and free of disease.
Hardisson Hernáez
D
D
Departamento de Anatomía Patológica, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Madrid, España.
Prim Espada
M P
MP
De Diego Sastre
J I
JI
Nistal Martín de Serrano
M
M
D000236:Adenoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006818:Hyalin / Q000378:metabolism*; D017154:Stromal Cells / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000601:surgery
Adenoma trabecular hialinizante de tiroides.