title: [Mixed anxiety and depression disorder: a naturalistic study].
abstract: BACKGROUND
  We sought to examine the prevalence, clinical characteristics and one-year outcome of Mixed Anxiety-Depressive Disorder (MADD) in a clinical sample.
  
  
  METHODS
  We interviewed 400 psychiatric outpatients, diagnosing MADD with DSM-IV research criteria.
  
  
  RESULTS
  Forty-two patients (10.5%) were diagnosed of MADD. Two-thirds were females, 50% had chronic medical conditions, 47.6% reported environmental problems, and the mean GAF was 54.4. At follow-up, MADD proved to be a stable diagnosis. Two subgroups emerged according to illness duration, with a chronic subtype (more than six months' duration) significantly different in the variable 12-month full remission.
  
  
  CONCLUSIONS
  MADD, an often disabling disorder, appears to be a frequent and stable diagnosis. We further suggest the existence of a distinct chronic subtype.
authors.affiliation: Serveis de Salut Mental, Sant Joan de Déu, Barcelona, Barcelona, 08025, España.
authors.forename: J
authors.initials: J
authors.lastname: Usall
authors.forename: M
authors.initials: M
authors.lastname: Márquez
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000150:complications* / Q000175:diagnosis* / Q000523:psychology; D002908:Chronic Disease; D003866:Depressive Disorder / Q000150:complications* / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012720:Severity of Illness Index
vernacular_title: Trastorno mixto ansioso-depresivo: un estudio naturalístico.