[Factors associated with survival in Kaposi's sarcoma in patients infected with the human immunodeficiency virus. Clinical Epidemiological Group for AIDS in Aquitaine].
BACKGROUND
To study behavioral risk factors of Kaposi's sarcoma (KS) among HIV infected homosexuals in Bordeaux, southwest France.


METHODS
A case-control study was performed within the Aquitaine Cohort. Cases of KS surviving in 1995 and homosexuals were systematically enrolled. For each case, two controls were selected among homosexuals surviving in the cohort. Cases and controls were matched on year of diagnosis of HIV infection. Data collection was based on a self administered questionnaire focusing on use of recreational drugs, detailed sexual practices and sexually transmitted diseases in the year preceeding the diagnosis of HIV infection, in the year after the HIV diagnosis and in the year preceeding the diagnosis of KS (or an equivalent period of time for controls).


RESULTS
Twelve cases were matched to 2 controls, 15 cases to one control and 13 cases remained unmatched. Matched analysis identified an association between KS and regular sexual partner (odds ratio = 0.07; 95% confidence interval: 0.01-0.52 and p < 0.001) and active and passive oro-anal intercourse before HIV diagnosis and before KS diagnosis (p = 0.01). In the unmatched analysis including all cases, we found an association between KS and the overall number of sexual partners (p < 0.03) for all periods of interest.


CONCLUSIONS
This case-control study identified sexual practices in favor of a sexually transmitted agent of KS.
Cazorla
C
C
Centre Hospitalier Universitaire, Département des maladies infectieuses, Hôpital Pellegrin, Bordeaux.
Dabis
F
F
Dupon
M
M
Ragnaud
J M
JM
Geniaux
M
M
Pellegrin
J L
JL
Salmi
L R
LR
D016022:Case-Control Studies; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000150:complications* / Q000635:transmission; D015438:Health Behavior; D007722:Health Knowledge, Attitudes, Practice; D006716:Homosexuality / Q000523:psychology / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D012307:Risk Factors; D012514:Sarcoma, Kaposi / Q000401:mortality* / Q000523:psychology / Q000821:virology*; D012747:Sexual Partners; D011795:Surveys and Questionnaires; D016019:Survival Analysis
Facteurs associés à la survenue de la maladie de Kaposi chez les patients infectés par le virus de l'immunodéficience humaine. Groupe d'Epidémiologie Clinique du SIDA en Aquitaine (GECSA).