[Clinical study of the effect of early enteral feeding on reducing hypermetabolism after server burns].
Hypermetabolism of burn patients is characterized by massive loss of lean body mass and obvious decrease of resistance. We evaluated the clinical effect of early enteral feeding on its modulating hypermetabolism in severe burn patients. The REEs (resting energy expenditure) decreased by 27.5%, 29.3%, 24.4% (average 27%) on PBD4, 8, 14 respectively in EFg (early feeding group) than those of DFg (delayed feeding group) (P < 0.05-0.01). To compare with the normal value, the mean REE was 138.8% in EFg, and 160% in DFg, the difference between two groups is significant (P < 0.05). Plasma glucagon, cortisol and urinary catecholamine markedly lowered and serum insulin obviously increased in EFg at most timepoints as compared with DFg (P < 0.05-0.01). It is indicated that early enteral feeding could reduce hypermetabolism after severe burn injury.
Wang
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Burn Research Institute, Southwestern Hospital, Third Military Medical University Chongqing.
Wang
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You
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D000293:Adolescent; D000328:Adult; D002056:Burns / Q000378:metabolism* / Q000628:therapy; D002395:Catecholamines / Q000652:urine; D004734:Energy Metabolism; D004750:Enteral Nutrition; D005260:Female; D005934:Glucagon / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013997:Time Factors
D002395:Catecholamines; D005934:Glucagon; D006854:Hydrocortisone