title: Retrospective analysis of neurapraxia and axonotmesis injuries of select peripheral nerves of the foot and ankle and their conservative and surgical treatment (external neurolysis and neurectomy).
abstract: There is a paucity of scientific literature that has reviewed the conservative and surgical treatment efficacy for the management of injuries causing neurapraxia and axonotmesis. This retrospective study evaluates the clinical outcomes of certain treatments for these injuries. Twenty-seven patients fulfilled the inclusion/exclusion criteria for the study, and represented both genders and a wide variety of ages, weights, levels of education, and backgrounds. Surgical intervention resulted in a slightly better clinical outcome when compared to conservative therapies. Patients undergoing surgery for a single nerve problem improved more than those who underwent surgery when three or more nerves were involved. Failure was most often associated with: 1) multiple nerve injuries, 2) a previous history of psychopathology, and 3) application of conservative therapy without surgical intervention for single nerve injury.
authors.affiliation: University of Pennsylvania Health System, Presbyterian Medical Center, Philadelphia, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Barrett
authors.forename: M S
authors.initials: MS
authors.lastname: Downey
authors.forename: H J
authors.initials: HJ
authors.lastname: Hillstrom
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D016512:Ankle Injuries / Q000209:etiology / Q000628:therapy; D002211:Capsaicin / Q000008:administration & dosage; D002648:Child; D005260:Female; D018409:Foot Injuries / Q000209:etiology / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000628:therapy*; D010543:Peroneal Nerve / Q000293:injuries*; D012189:Retrospective Studies; D013497:Sural Nerve / Q000293:injuries*; D016896:Treatment Outcome
chemical_list: D002211:Capsaicin