title: A new method for continuous tonometric pCO2 measurement--in vitro studies.
abstract: The available methods for tonometric pCO2 measurement only provide the possibility of performing intermittent registrations. A new method allowing continuous tonometric pCO2 measurement has been developed and tested in an in vitro model. A standard tonometer for intestinal pCO2 measurement was modified to allow continuous perfusion of the balloon with physiological saline solution in a closed system. The pCO2 in the system was determined in a specially constructed measurement chamber with a TCM20 percutaneous pCO2 monitor. In this in vitro model the tonometer balloon was placed in a saline bath with a constant pCO2 concentration and the measurements from the closed circulating system were compared with those obtained from a standard tonometer placed in the same bath. In 8 and 24 h experiments the circulating system measured the pCO2 value as accurately and reliably as traditional tonometry. This study indicates that the new method makes continuous monitoring of pCO2 possible.
authors.affiliation: Department of Surgery, University Hospital of Umeå, Sweden.
authors.forename: R
authors.initials: R
authors.lastname: Fröjse
authors.forename: C
authors.initials: C
authors.lastname: Arnerlöv
authors.forename: B
authors.initials: B
authors.lastname: Hedberg
authors.forename: M
authors.initials: M
authors.lastname: Haggström
authors.forename: T
authors.initials: T
authors.lastname: Bäcklund
authors.forename: O
authors.initials: O
authors.lastname: Lindahl
authors.forename: K A
authors.initials: KA
authors.lastname: Angquist
mesh_terms: D002138:Calibration; D002245:Carbon Dioxide / Q000032:analysis*; D002404:Catheterization; D017091:Colitis, Ischemic / Q000175:diagnosis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000378:metabolism*; D008365:Manometry / Q000295:instrumentation / Q000379:methods*; D012680:Sensitivity and Specificity; D013997:Time Factors
chemical_list: D002245:Carbon Dioxide