[Strains of Shigella sonnei recently isolated in Tokyo].
A total of 341 Shigella sonnei strains consisting of 94 domestic strains and 247 imported strains isolated during 1990-1997 in Tokyo, were examined regarding their colicine-type, drug-resistance and ornithine-utilization. The colicine typing results showed that the domestic strains were classified into 7 types, and the imported strains were classified into 13 types. Among the colicine-types identified, 8-type, 0-type, 6-type and 12-type were predominant in the domestic strains, whereas 6-type, 0-type, 8-type, 9A-type and 12-type were predominant in the imported strains. The drug-resistance test using 9 drugs (CP, TC, SM, KM, ABPC, ST, NA, FOM and NFLX) showed that 89.4% of the domestic strains and 85.4% of the imported strains were resistant to some of the drugs except FOM and NFLX. Drugs with a high resistant rate were SM, TC and ST for both groups. Drug-resistance patterns of the resistant strains varied in 22 types. Among those, a triple drug-resistance type with TC.SM.ST was found in the most frequent pattern in both groups. The results of the ornithine-utilization test revealed that 28.7% of the domestic strains and 8.1% of the imported strains were negative. The ornithine-negative strains in the same source had a similar plasmid-profile, but generally there was no correlation between the different sources.
Matsushita
S
S
Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health.
Konishi
N
N
Yanagawa
Y
Y
Kai
A
A
Morozumi
S
S
Igarashi
H
H
Morita
K
K
Kanamori
M
M
Kudoh
Y
Y
D004352:Drug Resistance, Microbial; D012764:Shigella sonnei / Q000302:isolation & purification*; D014041:Tokyo