HIV-associated eosinophilic folliculitis in an infant.
HIV-associated eosinophilic folliculitis (HIV-EF), which is a well-known entity in adults, has not been described in children. Although Ofuji's disease (OD) or eosinophilic pustular folliculitis (EPF) has been described in children and shares histopathologic features with HIV-EF, it is a distinct entity with characteristic clinical features. We report the occurrence of eosinophilic folliculitis in an 8-month-old HIV-positive patient and discuss the clinical, pathologic and possible pathogenetic aspects thereof. In addition, differences in the clinical manifestations of the present case and that of I-EPF are addressed. Because of clinicopathologic similarities between the present case and HIV-associated eosinophilic folliculitis (HIV-EF) in adults, we believe that eosinophilic folliculitis in this patient represents a cutaneous manifestation of HIV infection, rather than co-incidental occurrence of the infantile form of Ofuji's disease in an HIV-positive patient.
Ramdial
P K
PK
Department of Pathology, Faculty of Medicine, University of Natal, South Africa.
Morar
N
N
Dlova
N C
NC
Aboobaker
J
J
D000328:Adult; D004802:Eosinophilia / Q000175:diagnosis / Q000473:pathology*; D005499:Folliculitis / Q000175:diagnosis / Q000473:pathology*; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis; D018859:Hair Follicle / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D011379:Prognosis; D013492:Suppuration