title: Effect of intraperitoneal and extraperitoneal insertion of mesh on bacterial translocation: does it make a difference?
abstract: OBJECTIVE
  To asses the effect of insertion of mesh, with or without contact with the peritoneum, on the induction of bacterial translocation.
  
  
  METHODS
  Open experimental study.
  
  
  METHODS
  Surgical research laboratory, Turkey.
  
  
  METHODS
  158 Swiss albino mice.
  
  
  METHODS
  A defect in the abdominal wall was created. In the control group, the defect was closed primarily. In the extraperitoneal group, polypropylene mesh was sutured over the abdominal wall after primary closure of the peritoneum and in the intraperitoneal group, polypropylene mesh was sutured to close the created defect so that it was in contact with the intestines.
  
  
  METHODS
  Bacterial translocation at 4, 24 and 48 hours.
  
  
  RESULTS
  Insertion of mesh in contact with the peritoneum led to increased bacterial translocation to mesenteric lymph nodes at 4 (p = 0.02) and 48 (p = 0.03) hours compared with insertion without contact.
  
  
  CONCLUSIONS
  Contact between a foreign body and the peritoneum is required to induce bacterial translocation.
authors.affiliation: Department of General Surgery, Haccettepe University School of Medicine, Ankara, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Baykal
authors.forename: F
authors.initials: F
authors.lastname: Günbatili
authors.forename: O
authors.initials: O
authors.lastname: Aran
authors.forename: G
authors.initials: G
authors.lastname: Hasçelik
authors.forename: A
authors.initials: A
authors.lastname: Korkmaz
authors.forename: I
authors.initials: I
authors.lastname: Sayek
mesh_terms: D000009:Abdominal Muscles / Q000601:surgery; D000818:Animals; D018988:Bacterial Translocation; D008198:Lymph Nodes / Q000382:microbiology; D008643:Mesentery / Q000382:microbiology; D051379:Mice; D010537:Peritoneum / Q000601:surgery; D011126:Polypropylenes; D013526:Surgical Mesh; D013997:Time Factors
chemical_list: D011126:Polypropylenes