title: Methotrexate treatment for retained placental tissue.
abstract: Three cases of placental polyps not responding to conventional medical and surgical treatment are presented. In all three cases, hCG in serum was negative but despite this a single injection of methotrexate successfully treated the condition. It is suggested that methotrexate acts not only on dividing trophoblastic cells but also has other effects.
authors.affiliation: Department of Obstetrics and Gynaecology, Karolinska Hospital, Stockholm, Sweden.
authors.forename: F
authors.initials: F
authors.lastname: Flam
authors.forename: P O
authors.initials: PO
authors.lastname: Karlström
authors.forename: B
authors.initials: B
authors.lastname: Carlsson
authors.forename: L
authors.initials: L
authors.lastname: Garoff
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000627:therapeutic use*; D000328:Adult; D005260:Female; D005493:Folic Acid Antagonists / Q000627:therapeutic use*; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D019384:Nucleic Acid Synthesis Inhibitors / Q000627:therapeutic use*; D018457:Placenta, Retained / Q000188:drug therapy*; D011247:Pregnancy
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D005493:Folic Acid Antagonists; D019384:Nucleic Acid Synthesis Inhibitors; D008727:Methotrexate