title: Prolonged migraine aura without headache arrested by sumatriptan. A case report with further considerations.
abstract: The case of a 42-year-old woman with prolonged migraine visual aura without headache, whose long-lasting episodes of visual aura were successfully controlled by oral sumatriptan, is reported. Effectiveness of sumatriptan was unequivocal, since, after taking sumatriptan, duration of aura would drop from 1.5 h to approximately 20 min. This case suggests that sumatriptan may cross the blood-brain barrier and block spreading depression.
authors.affiliation: Departamento de Clínica Médica, Hospital de Clínicas da Universidade Federal do Paraná, Curitiba, Brazil. pak@cwb.palm.com.br
authors.forename: P A
authors.initials: PA
authors.lastname: Kowacs
authors.forename: E J
authors.initials: EJ
authors.lastname: Piovesan
authors.forename: C E
authors.initials: CE
authors.lastname: Tatsui
authors.forename: M C
authors.initials: MC
authors.lastname: Lange
authors.forename: L C
authors.initials: LC
authors.lastname: Ribas
authors.forename: L C
authors.initials: LC
authors.lastname: Werneck
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy*; D017366:Serotonin Receptor Agonists / Q000627:therapeutic use*; D018170:Sumatriptan / Q000627:therapeutic use*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D017366:Serotonin Receptor Agonists; D018170:Sumatriptan