Ariflo (SB 207499), a second generation phosphodiesterase 4 inhibitor for the treatment of asthma and COPD: from concept to clinic.
Torphy
T J
TJ
Division of Cardiovascular and Pulmonary Research, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania, 19406, USA.
Barnette
M S
MS
Underwood
D C
DC
Griswold
D E
DE
Christensen
S B
SB
Murdoch
R D
RD
Nieman
R B
RB
Compton
C H
CH
D001249:Asthma / Q000188:drug therapy*; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D017277:Drug Approval; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000188:drug therapy; D009570:Nitriles; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use*
D003509:Cyclohexanecarboxylic Acids; D009570:Nitriles; D010726:Phosphodiesterase Inhibitors; C433247:Cilomilast