title: Serum and urine selenium concentrations in patients with cardiovascular diseases and relationship to other nutritional indexes.
abstract: Serum and urine selenium levels were determined in patients with cardiovascular diseases by hydride generation atomic absorption spectrometry. Mean serum Se concentrations measured in patients with acute myocardial infarction (AMI; n = 32) or with ischemic cardiomyopathy (n = 50) were significantly lower than those determined in control groups. In AMI patients, serum triglyceride levels showed a positive significant correlation with the serum Se concentration (r = 0.59, p < 0.05). This result reinforces the important role of Se as an antioxidant agent in this disease. Mean urine Se concentrations of AMI patients (n = 33) were also significantly lower to those determined in the control group (p < 0. 05). This reaction of the organism contributes to regulate the Se homeostasis to keep the body Se status as high as possible.
authors.affiliation: Department of Nutrition and Bromatology, Faculty of Pharmacy, University of Granada, Granada, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Navarro-Alarcón
authors.forename: H
authors.initials: H
authors.lastname: López-Garcia de la Serrana
authors.forename: V
authors.initials: V
authors.lastname: Pérez-Valero
authors.forename: C
authors.initials: C
authors.lastname: López-Martínez
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000097:blood* / Q000652:urine*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000652:urine; D017202:Myocardial Ischemia / Q000097:blood / Q000652:urine; D009749:Nutrition Surveys; D009752:Nutritional Status; D012643:Selenium / Q000097:blood* / Q000652:urine*; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D012643:Selenium