Development of the mammalian enteric nervous system.
The mammalian enteric nervous system is derived from neural crest cells which invade the foregut and hindgut mesenchyme. It has been established that signalling molecules produced by the mesenchyme of the gut wall play a critical role in the development of the mammalian enteric nervous system. Recent studies have characterised further the role of such molecules and have identified novel extracellular and intracellular signals that are critical for enteric ganglia formation.
Taraviras
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Division of Developmental Neurobiology Medical Research Council National Institute for Medical Research The Ridgeway, Mill Hill, London, NW71AA, UK.
Pachnis
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D000818:Animals; D005314:Embryonic and Fetal Development / Q000502:physiology; D017615:Enteric Nervous System / Q000166:cytology / Q000196:embryology*; D008322:Mammals; D015398:Signal Transduction; D013234:Stem Cells / Q000166:cytology