[Myelopeptides as a new group of regulatory peptides].
The paper summarizes the data available on the structural and functional characteristics of the brain marrow immunoregulatory peptides myelopeptides (MPs). It describes the amino acid sequences of 6 individual MPs, their biological properties and mechanism. MP-1 is a hexapeptide having an immunocorrective effect. MP-2 has antitumor action, MP-3 stimulates the phagocytic activity of macrophages, M-4 is a new differentiating factor. The endogenous origin of the MPs isolated, their structure, and the pattern of their biological effects lead to the conclusion that MPs represent a new group of regulatory peptides that are promising for clinical application.
Mikhaĭlova
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AA
D000818:Animals; D001853:Bone Marrow / Q000276:immunology*; D002455:Cell Division / Q000187:drug effects; D006801:Humans; D007155:Immunologic Factors / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D009842:Oligopeptides / Q000737:chemistry / Q000494:pharmacology
D007155:Immunologic Factors; D009842:Oligopeptides; C048617:myelopeptides
Mielopeptidy - novaia gruppa reguliatornykh peptidov.