title: Use of variants of dihydrofolate reductase in gene transfer to produce resistance to methotrexate and trimetrexate.
authors.affiliation: Molecular Pharmacology and Therapeutics Program, Sloan Kettering Institute for Cancer Research, New York, N.Y., USA. bertinoj@mskcc.org
authors.forename: J R
authors.initials: JR
authors.lastname: Bertino
authors.forename: S C
authors.initials: SC
authors.lastname: Zhao
authors.forename: S
authors.initials: S
authors.lastname: Mineishi
authors.forename: E A
authors.initials: EA
authors.lastname: Ercikan-Abali
authors.forename: D
authors.initials: D
authors.lastname: Banerjee
mesh_terms: D004351:Drug Resistance / Q000235:genetics; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D018014:Gene Transfer Techniques; D014644:Genetic Variation; D008727:Methotrexate / Q000494:pharmacology*; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics*; D016597:Trimetrexate / Q000494:pharmacology*
chemical_list: D004791:Enzyme Inhibitors; D013762:Tetrahydrofolate Dehydrogenase; D016597:Trimetrexate; D008727:Methotrexate