title: [Study on microsatellite instability in gastric cancer].
abstract: OBJECTIVE
  To evaluate the microsatellite instability (MIN) in gastric cancers (GC).
  
  
  METHODS
  MIN was examined in 106 cases of GC, using the radioactive polymerase chain reaction-based method.
  
  
  RESULTS
  The frequency of MIN was significantly higher in expanding type of GC as compared with the infiltrative type (P < 0.005, chi 2 test). No significant association with histologic type, pTNM stage, age and sex was found (P > 0.05, chi 2 test).
  
  
  CONCLUSIONS
  These findings reveal that MIN might be an important contributor to the development and progress of a significant number of GC, especially the expanding type which, as acknowledged traditionally, has a favorable prognosis.
authors.affiliation: Department of Oncology, Union Hospital Affiliated to Fujian Medical University, Fuzhou.
authors.forename: J
authors.initials: J
authors.lastname: Cai
authors.forename: F
authors.initials: F
authors.lastname: You
authors.forename: X
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000235:genetics*