title: [Stereotactic radiosurgery with adjusted linear accelerator for cerebral arteriovenous malformations: preliminary results in the Netherlands].
abstract: OBJECTIVE
  To assess the effects of stereotactic radiosurgery of a cerebral arteriovenous malformation (AVM).
  
  
  METHODS
  Prospective.
  
  
  METHODS
  In November 1991-December 1995 linear acceleration radiosurgery was performed on 29 patients for their 30 cerebral AVMs in the University Hospital Vrije Universiteit, Amsterdam, the Netherlands. There were 15 females and 14 males with a mean age of 37.1 years (range: 13-58). Generally one isocentre was used and 15 Gy was given to the margins of the AVM at the 80% isodose. The mean target volume was 2.4 ml (range; 0.5-8.2). After 6 months, one year and thereafter every year, neurological and MRI-controls took place, in the outpatient ward. Angiography was performed after an average of 35 months (range: 24-70) to check if the AVM had obliterated.
  
  
  RESULTS
  Angiographic post-treatment results were available in 27 patients and MRI information in one. Angiographic obliteration occurred in 20 patients (71%). No permanent radiation-induced neurological deficit was seen, nor did any hemorrhage occur during the interval between irradiation and obliteration.
authors.affiliation: Afd. Neurochirurgie, Academisch Ziekenhuis Vrije Universiteit, Amsterdam.
authors.forename: J G
authors.initials: JG
authors.lastname: Wolbers
authors.forename: H C
authors.initials: HC
authors.lastname: Mol
authors.forename: J H
authors.initials: JH
authors.lastname: Kralendonk
authors.forename: O W
authors.initials: OW
authors.lastname: Meijer
authors.forename: J C
authors.initials: JC
authors.lastname: Baayen
authors.forename: B J
authors.initials: BJ
authors.lastname: Slotman
mesh_terms: D000293:Adolescent; D000328:Adult; D002533:Cerebral Angiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011829:Radiation Dosage; D016634:Radiosurgery / Q000379:methods*; D013238:Stereotaxic Techniques; D016896:Treatment Outcome
vernacular_title: Stereotactische radiochirurgie met aangepaste lineaire versneller voor cerebrale arterioveneuze malformaties: eerste ervaringen in Nederland.