title: [Mitotane treatment in a dog with a recurring adrenocortical carcinoma--a case report].
abstract: In a 7 year old female poodle an adrenocortical tumor was diagnosed on basis of laboratory and ultrasonographic examinations. One year after adrenalectomy, a relapse was diagnosed, at that time the suspicion of metastases in the liver arose for the first time. By treatment with Mitotane in a dose aiming at completely destroying the adrenal cortex, a complete disappearance of the tumor as well as a dramatic reduction of the size of the metastases could be achieved. 12 months after the begin of the chemotherapy, the dog is in good general condition.
authors.affiliation: Klinik für Kleintiermedizin, Fakultät Zürich.
authors.forename: M
authors.initials: M
authors.lastname: Keiser
authors.forename: M
authors.initials: M
authors.lastname: Flückiger
authors.forename: O
authors.initials: O
authors.lastname: Gardelle
authors.forename: C
authors.initials: C
authors.lastname: Reusch
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D002277:Carcinoma / Q000188:drug therapy / Q000556:secondary / Q000662:veterinary*; D003480:Cushing Syndrome / Q000209:etiology / Q000662:veterinary; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D004285:Dogs; D005260:Female; D008113:Liver Neoplasms / Q000556:secondary; D008939:Mitotane / Q000627:therapeutic use*; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000662:veterinary*; D014463:Ultrasonography
chemical_list: D018931:Antineoplastic Agents, Hormonal; D008939:Mitotane
vernacular_title: Mitotane-Behandlung bei einem Hund mit einem rezidivierenden Nebennierenrindenkarzinom--ein Fallbericht.