[Usefulness of routine investigation of fungal infections through bronchoscopy in HIV-infected and non-HIV-infected patients in a general hospital, reference to AIDS].
The diagnostic yields and the spectrum of pulmonary fungal-infection obtained in samples collected by fiberoptic bronchoscopy from HIV-positive and HIV-negative patients were evaluated from 1990 to 1995. A total of 1943 bronchoscopies were performed during this period, 47% in the HIV-positive group and 53% in the HIV-negative group. Of 908 HIV-positive patients, 38 (4%) had a fungus isolated from the pulmonary sample whereas of 1035 HIV-negative patients, only 4 (0.2%) had a fungus isolated. Histoplasmosis and Cryptococcosis were more frequently found in HIV-positive than in HIV-negative patients (p < 0.001). Paracoccidioides brasiliensis was found in only 3 patients, all of them immunocompetent. The study demonstrated that, despite the low yields, the HIV-positive group may benefit from routine screening for fungal elements in specimens obtained by fiberoptic bronchoscopy.
Lazzarini-de-Oliveira
L C
LC
Serviço de Pneumologia, Hospital Universitário Clementino Fraga Filho da Faculdade de Medicina da Universidade Federal do Rio de Janeiro. lazzarini@openlink.com.br
Arantes
A A
AA
Caiuby
M J
MJ
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis; D001999:Bronchoscopy; D003955:Diagnostic Tests, Routine; D015658:HIV Infections / Q000150:complications*; D018023:HIV Seronegativity; D006769:Hospitals, General; D006801:Humans; D008172:Lung Diseases, Fungal / Q000150:complications / Q000175:diagnosis*
Utilidade da investigação rotineira de infecção fúngica pela broncoscopia em pacientes infectados ou não pelo HIV em um hospital geral, referência para SIDA.