title: Inhibitory effect of some triterpenes from cacti on 32Pi-incorporation into phospholipids of HeLa cells promoted by 12-O-tetradecanoylphorbol-13-acetate.
abstract: Seventeen triterpenes isolated from cacti and the 10 derivatives were examined for the inhibition of tumor promoter-induced effects in vitro, such as stimulation of 32Pi-incorporation into phospholipids of cultured cells. Betulinic acid (1), cochalic acid (15), erythrodiol (16), oleanolic acid (21) and queretaroic acid (24) inhibited 12-O-tetradecanoylphorbol-13-acetate (TPA) stimulated 32Pi-incorporation into phospholipids of the cultured cells.
authors.affiliation: Department of Pharmacognocy and Phytochemistry, Meiji Pharmaceutical University, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kinoshita
authors.forename: Y
authors.initials: Y
authors.lastname: Yang
authors.forename: K
authors.initials: K
authors.lastname: Koyama
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Nishino
mesh_terms: D000818:Animals; D002273:Carcinogens / Q000494:pharmacology*; D002642:Chick Embryo; D006367:HeLa Cells; D006801:Humans; D010743:Phospholipids / Q000378:metabolism*; D010761:Phosphorus Radioisotopes / Q000378:metabolism*; D010944:Plants / Q000737:chemistry*; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology*; D014315:Triterpenes / Q000494:pharmacology*
chemical_list: D002273:Carcinogens; D010743:Phospholipids; D010761:Phosphorus Radioisotopes; D014315:Triterpenes; D013755:Tetradecanoylphorbol Acetate