title: [ATPase activity in neurons and neuroglia during convulsions induced by picrotoxin].
abstract: Na+,K(+)-ATPase activity was studied in neurones and neuroglia under conditions of convulsions caused by picrotoxin administration. Picrotoxin is a stimulant which causes convulsions by suppression of presynaptic inhibition. Na+,K(+)-ATPase activity in neuroglia was increased in convulsion, bat was not altered in neurones. It is possible, that glial Na+, K(+)-ATPase activity plays the role of neuronal ion's flows regulator and neuronal protector from convulsions. In recovery period ATPase activities in neuronal and neuroglial cells run up to control.
authors.affiliation: SPb-State University, I.P. Pavlov Physiological Institute, St.-Petersburg.
authors.forename: T I
authors.initials: TI
authors.lastname: Tolstukhina
authors.forename: M A
authors.initials: MA
authors.lastname: Flerov
mesh_terms: D000818:Animals; D003292:Convulsants / Q000633:toxicity; D008297:Male; D009457:Neuroglia / Q000201:enzymology*; D009474:Neurons / Q000201:enzymology*; D010852:Picrotoxin / Q000633:toxicity; D051381:Rats; D012640:Seizures / Q000139:chemically induced / Q000201:enzymology*; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*
chemical_list: D003292:Convulsants; D010852:Picrotoxin; D000254:Sodium-Potassium-Exchanging ATPase
vernacular_title: ATFaznaia aktivnost' v neĭronakh i neĭroglii pri sudorogakh, vyzvannykh pikrotoksinom.