title: Developmental regulation of dendritic cell function.
abstract: 1998 saw key advances in our understanding of the molecular mechanisms whereby immature dendritic cells recognise foreign pathogens in tissues and are induced to migrate to secondary lymphoid organs. In particular, there have been some key insights into how dendritic cells subsequently direct the evolution of immune responses by differential expression of co-stimulatory molecules.
authors.affiliation: MRC Centre for Immune Regulation, Department of Immunology and Infection, Medical School, University of Birmingham, Birmingham, B15 2TT, UK. p.j.l.lane@bham.ac.uk.
authors.forename: P J
authors.initials: PJ
authors.lastname: Lane
authors.forename: T
authors.initials: T
authors.lastname: Brocker
mesh_terms: D000818:Animals; D017951:Antigen Presentation; D001402:B-Lymphocytes / Q000276:immunology; D019013:CD40 Antigens / Q000378:metabolism; D002450:Cell Communication; D002454:Cell Differentiation; D018925:Chemokines / Q000378:metabolism; D003713:Dendritic Cells / Q000166:cytology* / Q000276:immunology*; D006801:Humans; D008954:Models, Biological; D009000:Monocytes / Q000166:cytology / Q000276:immunology; D010950:Plasma Cells / Q000166:cytology / Q000276:immunology; D015398:Signal Transduction; D016176:T-Lymphocyte Subsets / Q000276:immunology; D019444:Vaccines, DNA / Q000276:immunology
chemical_list: D019013:CD40 Antigens; D018925:Chemokines; D019444:Vaccines, DNA