title: [Hyalinizing trabecular adenoma of the thyroid].
abstract: Hyalinizing trabecular adenoma (HTA) is a follicle-derived tumor of the thyroid gland that has been described recently. The differential diagnosis includes medullar carcinoma, papillary carcinoma, and paraganglioma of the thyroid. We report a case of thyroid HTA in a 25-year-old woman. The tumor appeared as a <<cold nodule>> of the left thyroid in radionuclide scans. Histologically, the tumor showed tumor cells arranged in trabeculae and a prominent hyaline stroma. The neoplastic cells were focally immunoreactive for thyroglobulin and negative for calcitonin, chromogranin, and S-100 protein. Three years after hemithyroidectomy, the patient is alive and free of disease.
authors.affiliation: Departamento de Anatomía Patológica, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Madrid, España.
authors.forename: D
authors.initials: D
authors.lastname: Hardisson Hernáez
authors.forename: M P
authors.initials: MP
authors.lastname: Prim Espada
authors.forename: J I
authors.initials: JI
authors.lastname: De Diego Sastre
authors.forename: M
authors.initials: M
authors.lastname: Nistal Martín de Serrano
mesh_terms: D000236:Adenoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006818:Hyalin / Q000378:metabolism*; D017154:Stromal Cells / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000601:surgery
vernacular_title: Adenoma trabecular hialinizante de tiroides.