Spinal cord granulomatous vasculitis: an unusual clinical presentation of sarcoidosis.
A 52-year-old Caucasian man presented with isolated manifestations of myelopathy. Cervical magnetic resonance imaging showed a focus of increased signal intensity at the posterolateral left half of C5 and C6. Biopsy of spinal cord revealed the presence of active vasculitis associated with noncaseating granulomas. The patient responded to the combination of methotrexate (MTX) and corticosteroid treatment. Low-dose MTX was an effective, steroid-sparing regimen. This is a rare condition of isolated spinal cord involvement associated with sarcoid vasculitis.
Diri
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Department of Medicine, Louisiana State University School of Medicine at New Orleans, USA.
Espinoza
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CG
Espinoza
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D001706:Biopsy; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D012507:Sarcoidosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D013118:Spinal Cord Diseases / Q000175:diagnosis* / Q000473:pathology; D016896:Treatment Outcome; D014657:Vasculitis / Q000175:diagnosis*
D011241:Prednisone; D008727:Methotrexate