Ultrasound-induced temperature increase in guinea-pig fetal brain in utero: third-trimester gestation.
Temperature increase was measured at various depths in the brain of living fetal guinea pigs during in utero exposure to unscanned pulsed ultrasound at ISPTA 2.8 W/cm2. Mean temperature increases of 4.9 degrees C close to parietal bone and 1.2 degrees C in the midbrain were recorded after 2-min exposures. When exposures were repeated on the same sites in each fetus after death, the corresponding mean temperature increases were 4.9 degrees C and 1.3 degrees C, respectively. Cerebral blood perfusion had little cooling effect on ultrasound-induced heating in the guinea pig fetus of 57-61 days gestational age.
Horder
M M
MM
Department of Veterinary Clinical Sciences, University of Sydney, NSW Australia.
Barnett
S B
SB
Vella
G J
GJ
Edwards
M J
MJ
Wood
A K
AK
D000818:Animals; D001831:Body Temperature; D001921:Brain / Q000098:blood supply / Q000196:embryology*; D002560:Cerebrovascular Circulation; D005260:Female; D005865:Gestational Age; D006168:Guinea Pigs; D006358:Hot Temperature; D011247:Pregnancy; D012886:Skull / Q000196:embryology; D013997:Time Factors; D018617:Ultrasonography, Doppler, Pulsed / Q000009:adverse effects*; D016216:Ultrasonography, Prenatal / Q000009:adverse effects*