Viability and virulence of experimentally stressed nonculturable Salmonella typhimurium.
Maintenance of pathogenicity of viable but nonculturable Salmonella typhimurium cells experimentally stressed with UV-C and seawater, was investigated relative to the viability level of the cellular population. Pathogenicity, tested in a mouse model, was lost concomitantly with culturability, whereas cell viability remained undamaged, as determined by respiratory activity and cytoplasmic membrane and genomic integrities.
Caro
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A
Laboratoire Hydrobiologie, UMR CNRS-Université Montpellier II No. 5556, Université Montpellier II, F-34095 Montpellier cedex 5, France. acaro@email.unc.edu
Got
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P
Lesne
J
J
Binard
S
S
Baleux
B
B
D000818:Animals; D003470:Culture Media; D004195:Disease Models, Animal; D018869:Heat-Shock Response; D051379:Mice; D008810:Mice, Inbred C57BL; D012481:Salmonella Infections, Animal / Q000382:microbiology; D012486:Salmonella typhimurium / Q000254:growth & development* / Q000472:pathogenicity* / Q000502:physiology; D012623:Seawater / Q000382:microbiology; D014466:Ultraviolet Rays; D014774:Virulence
D003470:Culture Media