Prognostic factors in superficial adult soft tissue sarcomas: analysis of a series of 105 patients.
OBJECTIVE
This study was undertaken to study the behavior of superficial soft tissue sarcomas (STS) and determine the factors related to prognosis.


METHODS
The clinical records of 105 adults (56 men, 49 women, mean age: 56.4 years) were retrospectively analyzed. Univariate analysis was performed on the entire group for overall survival (OS), and metastasis-free survival (MFS). Local recurrence-free survival (LRFS) was studied only on patients first treated in our institute.


RESULTS
With a median follow-up of 111.9 months, 66 (62.9%) patients were alive; 25 (23.8%) had died of their disease. For the entire series, 10-year OS and MFS were 62.5% and 71.9% respectively. For fifty-two patients treated for their sarcoma at the Institution since the first tumor occurrence event, 10-year LRFS was 80%. Tumor grade was the only factor correlated with OS and MFS, while tumor size was the main factor correlated with LRFS.


CONCLUSIONS
Tumor size affects local control in STS while tumor grade is correlated with OS and MFS.
Cany
L
L
Department of Medical Oncology, Institut Bergonié Regional Cancer Center, Bordeaux, France.
Stoeckle
E
E
Coindre
J M
JM
Kantor
G
G
Bonichon
F
F
Bui
B N
BN
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D018219:Histiocytoma, Benign Fibrous / Q000401:mortality; D006801:Humans; D007890:Leiomyosarcoma / Q000401:mortality; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D012509:Sarcoma / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D015996:Survival Rate