Blue rubber bleb nevus (Bean syndrome): evolution of four cases and clinical response to pharmacologic agents.
Blue rubber bleb nevus (BRBN) syndrome is a rare disorder characterized by distinctive cutaneous and gastrointestinal vascular malformations. The latter may lead to bleeding complications. We followed four affected children for at least 5 years. The evolution of their disease and the value of pharmacologic agents (steroids, interferon) in the management of some of these patients are discussed.
Boente
M D
MD
Department of Dermatology, Hospital del Niño Jesus, Tucumán, Argentina.
Cordisco
M R
MR
Frontini
M D
MD
Asial
R A
RA
D001003:Anal Canal; D002648:Child; D002675:Child, Preschool; D005260:Female; D005528:Foot; D006471:Gastrointestinal Hemorrhage / Q000473:pathology*; D005770:Gastrointestinal Neoplasms / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D018329:Nevus, Blue / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*