title: Use of titanium prosthesis to bridge a vertebral gap in the spine--a preliminary experimental study.
abstract: Resection of a vertebral body for spine tumour or fracture results in a vertebral gap which has to be bridged by autogenous graft, allograft, bone cement or metal spacer. Recently, there have been several metal spacers in the market. We have designed a titanium vertebral spacer which is extensible by way of a threaded mechanism. Coating with hydroxyapatite enables bone ingrowth onto the surface of the titanium spacer. Biomechanical analysis, using the Instron biaxial electro-servohydraulic testing machine, showed that the segment bridging the spacer was rigid and stiffer than the adjacent vertebral body motion segment. Histological study showed that there was bone growth across the vertebral gap indicating fusion had taken place.
authors.affiliation: Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.
authors.forename: I S
authors.initials: IS
authors.lastname: Rikhraj
authors.forename: C T
authors.initials: CT
authors.lastname: Tan
authors.forename: S K
authors.initials: SK
authors.lastname: Tan
authors.forename: S H
authors.initials: SH
authors.lastname: Teoh
authors.forename: G W
authors.initials: GW
authors.lastname: Hastings
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D020099:Coated Materials, Biocompatible; D017886:Durapatite; D020007:Implants, Experimental; D008159:Lumbar Vertebrae / Q000601:surgery*; D019736:Prostheses and Implants; D011474:Prosthesis Design; D019919:Prosthesis Implantation; D013131:Spine / Q000502:physiology; D013552:Swine; D014025:Titanium
chemical_list: D020099:Coated Materials, Biocompatible; D017886:Durapatite; D014025:Titanium