title: The virtual cell.
abstract: This paper describes a computational framework for cell biological modeling and simulation that is based on the mapping of experimental biochemical and electrophysiological data onto experimental images. The framework is designed to enable the construction of complex general models that encompass the general class of problems coupling reaction and diffusion.
authors.affiliation: Department of Physiology, University of Connecticut Health Center, Farmington 06030, USA.
authors.forename: J
authors.initials: J
authors.lastname: Schaff
authors.forename: L M
authors.initials: LM
authors.lastname: Loew
mesh_terms: D002468:Cell Physiological Phenomena; D019295:Computational Biology / Q000379:methods*; D003198:Computer Simulation; D003205:Computing Methodologies; D004594:Electrophysiology / Q000379:methods; D008954:Models, Biological; D012984:Software; D014584:User-Computer Interface