title: Early experience with partial left ventriculectomy in the Asia-Pacific region.
abstract: BACKGROUND
  We report our early experience with partial left ventriculectomy done by a group of cardiac surgeons in the Asia-Pacific region.
  
  
  METHODS
  Partial left ventriculectomy was done in 48 patients (mean age, 43 years) with advanced symptomatic cardiomyopathy. The origin of cardiomyopathy was idiopathic in 30 patients, valvular in 10, ischemic in 3, peripartum in 3, sarcoidosis in 1, and viral myocarditis in 1. Procedures performed on the mitral valve were repair with Alfieri method in 8 patients, ring annuloplasty in 2, and replacement in 25.
  
  
  RESULTS
  Seventy-seven percent of patients required myocardial support for weaning from cardiopulmonary bypass, and the overall in-hospital mortality rate was 27%. Mean follow up was 6.5 months (range, 1 to 18 months), and patient survival at 1, 3, and 6 months after discharge was 91%, 88%, and 84%, respectively. Sixty-five percent of survivors with idiopathic and valvular disease achieved significant and sustained improvement in ventricular contractility and symptoms, but there were no clear symptomatic benefits from partial left ventriculectomy in patients with cardiomyopathy from other causes. Most cases of late recurrence of heart failure symptoms (90%) appeared to be related to the development of progressive mitral incompetence.
  
  
  CONCLUSIONS
  After partial left ventriculectomy left ventricular function improved in patients with idiopathic and valve related cardiomyopathies. Late deterioration was related to the development of significant mitral valve incompetence postoperatively, hence definitive mitral valve repair or replacement at the time of the partial left ventriculectomy procedure is advised.
authors.affiliation: Prince of Wales Hospital, Hong Kong. izzat@cyberia.net.lb
authors.forename: M B
authors.initials: MB
authors.lastname: Izzat
authors.forename: S S
authors.initials: SS
authors.lastname: Kabbani
authors.forename: H
authors.initials: H
authors.lastname: Suma
authors.forename: K
authors.initials: K
authors.lastname: Pandey
authors.forename: K
authors.initials: K
authors.lastname: Morishita
authors.forename: A P
authors.initials: AP
authors.lastname: Yim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001208:Asia; D009202:Cardiomyopathies / Q000503:physiopathology / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D005260:Female; D006333:Heart Failure / Q000503:physiopathology / Q000601:surgery*; D006352:Heart Ventricles / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D016277:Ventricular Function, Left