title: Vagal nerve stimulator: a new approach to medically refractory epilepsy.
abstract: Repetitive vagal nerve stimulation (VNS) is a new, FDA-approved treatment for medically refractory epilepsy. The device is implanted subcutaneously in the left chest and sends intermittent impulses to the left vagus nerve through communicating leads. Twelve patients have been implanted to date. The ages of the patients range from 8 to 36 years and the average followup at this point is five months. Five patients have achieved a greater than 50 percent reduction in seizure frequency with no serious adverse effects.
authors.affiliation: New York University Medical School, USA.
authors.forename: R B
authors.initials: RB
authors.lastname: FineSmith
authors.forename: E
authors.initials: E
authors.lastname: Zampella
authors.forename: O
authors.initials: O
authors.lastname: Devinsky
mesh_terms: D000293:Adolescent; D000328:Adult; D002531:Cerebellum / Q000098:blood supply; D002648:Child; D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D004827:Epilepsy / Q000628:therapy*; D005260:Female; D006801:Humans; D020007:Implants, Experimental / Q000009:adverse effects; D008125:Locus Coeruleus / Q000503:physiopathology; D008280:Magnetics / Q000627:therapeutic use; D008297:Male; D013702:Temporal Lobe / Q000098:blood supply; D013788:Thalamus / Q000098:blood supply; D014630:Vagus Nerve / Q000503:physiopathology*