title: Colorectal cancer in adolescents.
abstract: Colorectal cancer, one of the most common malignancies among adults, is rare in adolescence. This low incidence coupled with non-specific symptoms and aggressive natural history leads to a poorer prognosis than in reported adult series. This article describes two cases of colorectal cancer in adolescents and reviews the literature regarding this rare condition. Earlier diagnosis and a greater understanding of the natural history may lead to improved treatment with concomitant improvements in survival.
authors.affiliation: Department of Surgery, UCL Medical School, London.
authors.forename: A
authors.initials: A
authors.lastname: Shankar
authors.forename: A J
authors.initials: AJ
authors.lastname: Renaut
authors.forename: J
authors.initials: J
authors.lastname: Whelan
authors.forename: I
authors.initials: I
authors.lastname: Taylor
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D003106:Colon / Q000000981:diagnostic imaging; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000556:secondary*; D008297:Male; D014057:Tomography, X-Ray Computed
chemical_list: D002945:Cisplatin; D002955:Leucovorin; D005472:Fluorouracil