title: High-density assessment of the IHS classification criteria for migraine without aura: a prospective study.
abstract: Fifty-six adult female patients with the clinical diagnosis of MwoA kept a diary 6 times per day for 10 consecutive weeks to record the occurrence, pain characteristics, and accompanying symptoms of headache. In order to avoid bias due to retrospection or expectancy the diary was programmed into palmtop computers which signaled the patients with a beep to enter the diary with a random-fixed time schedule: two signals occurred in, respectively, the morning, the afternoon, and the evening, but at different times for each day. The palmtop computers also warranted flawless data storage and automatic computations of response delay and missing values. Of the 339 attacks, 75% had a duration of 4-72 h and 94% confirmed the International Headache Society classification criteria for MwoA concerning pain characteristics and accompanying symptoms. Our results obtained for attacks in treated patients are highly comparable with the results of Rasmussen, Jensen, and Olesen (1991) obtained in the general population with unknown treatment of headache. Together, both studies support the IHS classification criteria for MwoA. The electronic Experience Sampling Method also allowed for an unbiased description of the course of treated MwoA attacks: 67% subsided in the first day. In the 16 attacks the characteristics and accompanying symptoms were present in 60-80% of the attacks at the first assessment (9.30 a.m.) with the exception of moderate to severe pain intensity (37%) and nausea or vomiting (31%). A waxing and waning of characteristics and symptoms over the day remained in about 30-40% of the attacks with a tendency towards increases in the evening (7.30 p.m. and 10 p.m.). The method is there for a replication of this study in untreated MwoA patients.
authors.affiliation: Department of Health Psychology, Utrecht University, The Netherlands.
authors.forename: P C
authors.initials: PC
authors.lastname: Honkoop
authors.forename: M J
authors.initials: MJ
authors.lastname: Sorbi
authors.forename: G L
authors.initials: GL
authors.lastname: Godaert
authors.forename: E L
authors.initials: EL
authors.lastname: Spierings
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007391:International Cooperation; D008499:Medical Records; D008875:Middle Aged; D008881:Migraine Disorders / Q000145:classification*; D011446:Prospective Studies; D012955:Societies, Medical