Aromin-A, an Annonaceous acetogenin from Annona cherimola.
Chromatographic fractionation of a MeOH extract from the stems of Annona cherimola led to the isolation of a new non-adjacent, bis-THF ring acetogenin (one THF ring being at C-4 and the other at C-16), aromin-A (1) along with the known cytotoxic acetogenin squamocin (2). The structures of these isolates were established by means of mass spectrometry and spectroscopic techniques.
Chen
C Y
CY
Graduate Institute of Natural Products, Kaohsiung Medical College, Taiwan.
Chang
F R
FR
Chiu
H F
HF
Wu
M J
MJ
Wu
Y C
YC
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D002470:Cell Survival / Q000187:drug effects; D002855:Chromatography, Thin Layer; D005663:Furans / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D018547:Plant Stems; D010946:Plants, Medicinal; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D005663:Furans; D007783:Lactones; C120241:aromin-A