title: Iridoid and seco-iridoid glucosides from Chioccoca alba (Rubiaceae).
abstract: Phytochemical investigation of Chioccoca alba afforded three new iridoids, alboside I, alboside II and alboside III, and a new seco-iridoid alboside V. Alboside IV showed moderate activity towards the DNA repair-deficient mutant RS321 of Saccharomyces cerevisiae. The structural elucidation of the new compounds was performed by ES-MS and by 1D and 2D NMR spectroscopic methods.
authors.affiliation: Instituto de Química, Universidade Estadual Paulista, Araraquara, SP, Brazil.
authors.forename: C A
authors.initials: CA
authors.lastname: Carbonezi
authors.forename: D
authors.initials: D
authors.lastname: Martins
authors.forename: M C
authors.initials: MC
authors.lastname: Young
authors.forename: M N
authors.initials: MN
authors.lastname: Lopes
authors.forename: M
authors.initials: M
authors.lastname: Furlan
authors.forename: E
authors.initials: E
authors.lastname: Rodriguez Filho
authors.forename: V da S
authors.initials: Vda S
authors.lastname: Bolzani
mesh_terms: D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D039823:Iridoids; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D011714:Pyrans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019666:Rubiaceae / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D013057:Spectrum Analysis
chemical_list: D005960:Glucosides; D039823:Iridoids; D011714:Pyrans