title: Analysis of risk factors associated with nosocomial bacteraemias.
abstract: A prospective study of 2676 blood cultures was performed to identify the factors associated with clinically, significant nosocomial bacteraemia that occurred during a one year period in the Malaga University Clinical Hospital. Three hundred and fifty-five episodes of bacteraemia were considered clinically significant. The overall incidence of bacteraemia was 19.5/1000 admissions, of which 46% were hospital-acquired. A multivariate model showed that only six factors were significantly, and independently, responsible for nosocomial bacteraemias: intravascular catheterization (P < 0.0001, OR = 18.37), invasive procedures (P < 0.0001, OR = 10.38), malignancy (P = 0.035, OR = 3.11), indwelling devices (P = 0.005, OR = 3.05), stay in intensive care or surgical departments (P = 0.05, OR = 2.63) and length of hospital stay (P = 0.051, OR = 1.02). These results show that the factors which had most influence on the development of nosocomial bacteraemias were those factors associated with the treatment received by patients during their hospital stay.
authors.affiliation: Microbiology Service, Hospital Clinico, University of Malaga, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Rojo
authors.forename: A
authors.initials: A
authors.lastname: Pinedo
authors.forename: E
authors.initials: E
authors.lastname: Clavijo
authors.forename: A
authors.initials: A
authors.lastname: García-Rodriguez
authors.forename: V
authors.initials: V
authors.lastname: García
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D016470:Bacteremia / Q000453:epidemiology / Q000517:prevention & control*; D003428:Cross Infection / Q000453:epidemiology / Q000517:prevention & control*; D005260:Female; D006785:Hospitals, University; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011446:Prospective Studies; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology