Acute, fatal, oral chromic acid poisoning.
We report a 35-year-old woman who developed severe acidosis, massive gastrointestinal hemorrhage, acute renal failure, and hepatic injury following ingestion of chromic acid (50 mL) and died 12 hours after ingestion. Postmortem liver biopsy revealed a fatty degeneration with chromium concentration 3.6 mumol/g. The kidney, with chromium concentration 2.6 mumol/g, had extensive necrosis and ischemic lesions. Erythrocyte chromium was 1903 mumol/L at 3 hours declining to 865 mumol/L at 11 hours.
Loubières
Y
Y
Ambroise Paré Hospital, Louis Mourier Hospital, Colombes, France. yloubier@world.net.fr
de Lassence
A
A
Bernier
M
M
Vieillard-Baron
A
A
Schmitt
J M
JM
Page
B
B
Jardin
F
F
D000208:Acute Disease; D058186:Acute Kidney Injury / Q000097:blood / Q000139:chemically induced; D000284:Administration, Oral; D000328:Adult; D056486:Chemical and Drug Induced Liver Injury; D002840:Chromates / Q000097:blood / Q000506:poisoning*; D004912:Erythrocytes / Q000378:metabolism; D017809:Fatal Outcome; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000097:blood / Q000139:chemically induced; D006801:Humans; D008107:Liver Diseases / Q000097:blood; D013405:Suicide
D002840:Chromates; C034944:chromic acid