title: The human herpesvirus-type 8 is not involved in malignant melanoma.
abstract: Malignant melanomas were supposed to harbour the human herpesvirus-type 8 (HHV-8) genome, as melanoma cells were reported to express interleukin-6 and a homologue of interleukin-6 was found in the HHV-8 genome. We therefore investigated 33 primary malignant melanomas by polymerase chain reaction, but could not find this tumorigenic gamma-herpesvirus in any tumour.
authors.affiliation: Universitäts-Hautklinik Heidelberg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Deichmann
authors.forename: M
authors.initials: M
authors.lastname: Thome
authors.forename: M
authors.initials: M
authors.lastname: Bock
authors.forename: A
authors.initials: A
authors.lastname: Jäckel
authors.forename: V
authors.initials: V
authors.lastname: Waldmann
authors.forename: H
authors.initials: H
authors.lastname: Näher
mesh_terms: D004279:DNA, Viral / Q000302:isolation & purification; D019288:Herpesvirus 8, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D015850:Interleukin-6 / Q000235:genetics; D008545:Melanoma / Q000473:pathology / Q000821:virology*; D016133:Polymerase Chain Reaction
chemical_list: D004279:DNA, Viral; D015850:Interleukin-6