[Clinical and immunological criteria for predicting the course of uveitis].
Clinical and immunological parameters are studied in 205 patients with uveites of different etiology in order to define the criteria permitting the prediction of uveitis course and relapses. The prognosis is unfavorable for autoimmune conditions, including peripheral, systemic, syndromal, tuberculous uveites and mixed infections. Clinical cure is unstable in diffuse inflammatory changes, persistent cellular infiltration of the vitreous body, formation of cyclic membranes in it, in cataract complications, and exudative hemorrhagic chorioretinitis. High titers of antibodies to tissue antigens and deficiency or hyperimmunoglobulinemia A, discoordination of T and B immunity, and sensitization to several antigens are risk factors for relapses. Clinical and immunological parameters should be analyzed for predicting the disease course and prescribing the basic and antirelapse therapy.
Chentsova
O B
OB
D001323:Autoantibodies / Q000276:immunology; D001324:Autoantigens / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology; D011379:Prognosis; D012008:Recurrence; D013601:T-Lymphocytes / Q000276:immunology*; D014605:Uveitis / Q000209:etiology* / Q000276:immunology
D001323:Autoantibodies; D001324:Autoantigens; D007070:Immunoglobulin A
Kliniko-immunologicheskie kriterii prognoza techeniia uveitov.