[Helicobacter pylori and congestive gastropathy].
OBJECTIVE
This study evaluates the prevalence and significance of Helicobacter pylori(H. pylori) infection in patients with portal hypertension.


METHODS
177 patients were selected. Among whom, 135 patients with portal hypertension and 42 noncirrhotic patients with nonulcerative dyspepsia as a control group. In all patients diagnostic upper endoscopy was performed and gastric biopsies were taken for histological examination and diagnosis of H. pylori infection.


RESULTS
Of the portal hypertensive patients, 63 patients had congestive gastropathy, 17(27%) of whom were positive for H. pylori infection and 72 patients did not have gastropathy, 18(25%) of whom were positive for H. pylori infection. In the control group 23 of 42(55%) were positive for H. pylori infection. H. pylori was found less frequently in congestive gastropathy patients than in the control group. We also found that the presence and severity of congestive gastropathy is independent of the H. pylori status.


CONCLUSIONS
The role of H. pylori infection in the pathogenesis of congestive gastropathy seems to be unlikely and we suggest that there is no need for its routine eradication in cirrhotic patients.
Dai
L
L
Second Affiliated Hospital, Chongqing Department of Gastroenterology Medical University.
Wu
X
X
D000328:Adult; D000368:Aged; D005260:Female; D016481:Helicobacter Infections / Q000150:complications*; D016480:Helicobacter pylori; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications*; D008297:Male; D008875:Middle Aged; D013272:Stomach Diseases / Q000209:etiology*