Myotonia associated with sarcoidosis: marked exacerbation with pravastatin.
A 37-year-old man with sarcoidosis developed severe electrical and clinical myotonia while taking pravastatin for hypercholesterolemia. Myotonia associated with sarcoidosis is rare. Pravastatin is associated with myotonia in animals. This case suggests that sarcoidosis and pravastatin, two entities not frequently associated with myotonia, may interact in a synergistic manner to produce severe clinical myotonia in humans.
Riggs
J E
JE
Department of Neurology, West Virginia University School of Medicine, Morgantown 26506-9180, USA.
Schochet
S S
SS
D000328:Adult; D000924:Anticholesteremic Agents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009222:Myotonia / Q000139:chemically induced / Q000150:complications*; D017035:Pravastatin / Q000009:adverse effects*; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy
D000924:Anticholesteremic Agents; D017035:Pravastatin