title: Transitional cell carcinoma arising in a pyelocaliceal cyst. An unusual cystic renal lesion with cytologic and imaging findings.
abstract: The differentiation between benign and malignant cystic lesions of the kidney is a diagnostic challenge. Medical imaging aids in this task, but many cystic renal lesions require further work-up, frequently by computed tomography-guided fine needle aspiration. We report on the pathological findings in a case of moderately differentiated papillary transitional carcinoma, which arose in a pre-existing pyelocaliceal cyst in a 53-year-old man. In the case of this lesion, the distinction between a benign and a malignant renal cyst is blurred. To our knowledge, this is the third such occurrence to be reported and the first to be diagnosed by fine needle aspiration biopsy.
authors.affiliation: Department of Pathology and Laboratory Medicine, Department of Veterans Affairs Medical Center, Syracuse, NY 13210, USA. friedmah@worldnet.att.net
authors.forename: H D
authors.initials: HD
authors.lastname: Friedman
authors.forename: I S
authors.initials: IS
authors.lastname: Nsouli
authors.forename: D J
authors.initials: DJ
authors.lastname: Krauss
authors.forename: S
authors.initials: S
authors.lastname: Vohra
authors.forename: C N
authors.initials: CN
authors.lastname: Powers
mesh_terms: D001707:Biopsy, Needle; D002295:Carcinoma, Transitional Cell / Q000473:pathology* / Q000601:surgery; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000473:pathology* / Q000601:surgery; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D007682:Kidney Pelvis / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy