Multichannel laser-Doppler probe for blood perfusion measurements with depth discrimination.
The laser-Doppler method is frequently used in clinical experiments for blood perfusion measurement. A multichannel laser-Doppler probe was constructed, and calibrated and evaluated using a flow model and real examination of healthy subjects. Results obtained on a three-capillary flow model suggest that the probe can be used to obtain information from superficial and deeper layers of the tissue. The influence of the optical arrangement of the laser-Doppler probe on the parameters of post-occlusive reactive hyperaemia was investigated in a group of 15 healthy subjects. A statistically significant increase of biological zero with distance between emitting and detecting fibres was noted.
Liebert
A
A
Institute of Biocybernetics and Biomedical Engineering PAS, Warsaw, Poland. aliebert@ibib.waw.pl
Leahy
M
M
Maniewski
R
R
D006801:Humans; D006940:Hyperemia / Q000175:diagnosis; D017078:Laser-Doppler Flowmetry / Q000295:instrumentation*; D008833:Microcirculation; D008955:Models, Cardiovascular; D012815:Signal Processing, Computer-Assisted