title: Treatment of port-wine stains with a noncoherent pulsed light source: a retrospective study.
abstract: OBJECTIVE
  We investigated whether a noncoherent intense pulsed light source (IPLS) would be effective in therapy of port-wine stains (PWSs).
  
  
  METHODS
  To evaluate the efficacy in treatment of PWSs with IPLS, a retrospective study was initiated.
  
  
  METHODS
  The data were collected by physicians working in private practices and departments of university hospitals and medical centers, respectively.
  
  
  METHODS
  A total of 37 randomly selected patients with a total of 40 PWSs were included in the study. Clinical PWS characteristics recorded were color and location of the PWS.
  
  
  METHODS
  All patients were treated with IPLS.
  
  
  METHODS
  Data collected included treatment parameter (filters, pulse duration, fluence, and pulse sequencing), percentage of clearance, and side effects (purpura, blisters, crusting, altered pigmentation, and scarring).
  
  
  RESULTS
  Good and complete (70%-100%) clearance was achieved in 28 of 40 PWSs treated with IPLS. The average number of treatment sessions in PWSs reaching 100% clearance included 4.0 for pink PWSs and 1.5 for red PWSs. The average number of sessions for purple PWSs reaching good clearance (70%-99%) was 4.2 sessions. Parameters used most frequently were 515- and 550-nm cut-off filters, pulse duration of 2.5 to 5.0 milliseconds, and fluences of 24 to 60 J/cm2. Side effects included purpura in 133 (76%), superficial blisters in 14 (8%), and crusting in 35 (20%). Transient pigmentation changes were seen in 10.8% of patients (hypopigmentation in 3 [8.1%], hyperpigmentation in 1 [2.7%]). No scarring was observed.
  
  
  CONCLUSIONS
  Intense pulsed light source presents an effective and safe method for treating PWSs, especially purple PWSs.
authors.affiliation: Laserklinik, Karlsruhe, Germany. dres.raulin@t-online.de
authors.forename: C
authors.initials: C
authors.lastname: Raulin
authors.forename: C A
authors.initials: CA
authors.lastname: Schroeter
authors.forename: R A
authors.initials: RA
authors.lastname: Weiss
authors.forename: M
authors.initials: M
authors.lastname: Keiner
authors.forename: S
authors.initials: S
authors.lastname: Werner
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006222:Hamartoma / Q000628:therapy*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010789:Phototherapy / Q000379:methods*; D012189:Retrospective Studies; D012871:Skin Diseases / Q000628:therapy*