Disseminated intravascular coagulation in a patient undergoing removal of humeral head for pain relief.
Disseminated intravascular coagulation (DIC) was recently observed intraoperatively in a patient who required removal of her right humeral head for pain relief. Despite normal preoperative coagulation parameters, the patient developed wound oozing soon after suturing the skin. Coagulation profile revealed decreased platelets, plasma coagulation factors and fibrinogen in association with elevated fibrin degradation products. To manage the DIC, urinastatin and gabexate mesilate, along with blood component replacement, proved effective.
Terasako
K
K
Division of Anesthesia, Kyoto Katsura Hospital, Japan.
D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D001803:Blood Transfusion; D004211:Disseminated Intravascular Coagulation / Q000209:etiology* / Q000628:therapy; D005260:Female; D016670:Gabexate / Q000627:therapeutic use; D006023:Glycoproteins / Q000627:therapeutic use; D006801:Humans; D006810:Humeral Fractures / Q000601:surgery; D006811:Humerus / Q000601:surgery*; D007431:Intraoperative Complications / Q000628:therapy*; D014361:Trypsin Inhibitors / Q000627:therapeutic use
D000925:Anticoagulants; D006023:Glycoproteins; D014361:Trypsin Inhibitors; D016670:Gabexate; C028665:urinastatin