Interleukin-12 in human milk.
The presence of interleukin-12 (IL-12) in 39 samples of human milk was investigated using the enzyme-linked immunosorbent assay. IL-12 (>40 pg/mL) was detected in 24 of the 39 samples collected (1408 +/- 2256 pg/mL, mean +/- SD, n = 24). A range of concentrations of IL-12 was observed in colostrum, transitional, and mature milk, with an apparent decrease in the mean concentration over time postpartum.
Bryan
D L
DL
Child Nutrition Research Centre, Flinders University of South Australia, Australia.
Hawkes
J S
JS
Gibson
R A
RA
D000293:Adolescent; D000328:Adult; D003126:Colostrum / Q000276:immunology; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018664:Interleukin-12 / Q000032:analysis*; D008895:Milk, Human / Q000276:immunology*; D049590:Postpartum Period; D018417:Th1 Cells / Q000276:immunology; D018418:Th2 Cells / Q000276:immunology; D013997:Time Factors
D018664:Interleukin-12