Bioactive N-isobutylamides from the flower buds of Spilanthes acmella.
The hexane extract of dried flower buds of Spilanthes acmella afforded three N-isobutyl amides: spilanthol, undeca-2E,7Z,9E-trienoic acid isobutylamide and undeca-2E-en-8,10-diynoic acid isobutylamide. Their structures were determined by 1H and 13C NMR, MS and GC-MS spectroscopic methods. All were active against Aedes aegyptii larvae and Helicoverpa zea neonates at 12.5 and 250 micrograms/mL concentrations, respectively.
Ramsewak
R S
RS
Department of Horticulture, Michigan State University, East Lansing 48824, USA.
Erickson
A J
AJ
Nair
M G
MG
D000577:Amides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D019659:Asteraceae / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D009033:Culicidae / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry / Q000379:methods; D015394:Molecular Structure
D000577:Amides