[c-met expression in human hepatocellular cancer].
Using Northern blot method, we examined the expression of c-met in human hepatocellular cancer. Of 30 patients tested, the expression of c-met mRNA was not significantly different in HCC tissues from corresponding noncancerous parenchyma (P > 0.05). There was no significant relationship between c-met expression and grade of differentiation, stage of clinic, AFP, HBsAg (P > 0.05). Our results suggest that c-met may play different roles in the pathogenesis and metastasis of human hepatocellular carcinoma.
Liu
R
R
Department of Hepatobiliary Surgery, General Hospital of People's Liberation Army, Beijing.
Wu
M
M
Liu
Y
Y
D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000378:metabolism*; D005260:Female; D015870:Gene Expression; D006801:Humans; D008113:Liver Neoplasms / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D019859:Proto-Oncogene Proteins c-met / Q000096:biosynthesis* / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics
D012333:RNA, Messenger; D019859:Proto-Oncogene Proteins c-met