title: Familial occurrence of congenital hypothyroidism due to lingual thyroid gland.
abstract: Two sisters who presented with midline neck masses proved to be biochemically hypothyroid. Thyroid scintigraphy supplemented with perchlorate discharge testing showed lingual thyroid glands and ruled out the expected autosomal recessive organification defect. The related literature is reviewed.
authors.affiliation: Department of Medicine, College of Medicine and King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia. nuclear@k.s.u.edu.sa
authors.forename: M I
authors.initials: MI
authors.lastname: El-Desouki
authors.forename: A S
authors.initials: AS
authors.lastname: Al-Herbish
authors.forename: N A
authors.initials: NA
authors.lastname: Al-Jurayyan
mesh_terms: D000328:Adult; D002648:Child; D002828:Choristoma / Q000150:complications / Q000000981:diagnostic imaging*; D003409:Congenital Hypothyroidism; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013670:Sodium Pertechnetate Tc 99m; D013961:Thyroid Gland / Q000002:abnormalities* / Q000000981:diagnostic imaging; D014060:Tongue Diseases / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging*
chemical_list: D019275:Radiopharmaceuticals; D013670:Sodium Pertechnetate Tc 99m