Rapid progression to high-grade dysplasia in Barrett's esophagus after liver transplantation.
There is an increased incidence of malignancies in transplant recipients. Accelerated progression from a premalignant lesion to carcinoma has been reported in transplant recipients with skin cancer and colon cancer. Whereas Barrett's esophagus is a common premalignant condition in the normal population, rapid progression to severe dysplasia or carcinoma has not been widely reported in transplant recipients. We report on a liver transplant recipient who developed rapid progression from Barrett's esophagus without dysplasia to high-grade dysplasia within 9 months after transplantation.
Trotter
J F
JF
Division of Gastroenterology, Liver Transplant Service, Duke University Medical Center, Durham, NC 27710, USA.
Brazer
S R
SR
D000328:Adult; D001471:Barrett Esophagus / Q000473:pathology* / Q000503:physiopathology; D018450:Disease Progression; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000503:physiopathology; D006526:Hepatitis C / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008103:Liver Cirrhosis / Q000601:surgery / Q000821:virology; D016031:Liver Transplantation / Q000009:adverse effects; D008297:Male; D008679:Metaplasia; D011230:Precancerous Conditions / Q000473:pathology* / Q000503:physiopathology
D007166:Immunosuppressive Agents