title: Evaluation of the role of magnetic resonance myelography in lumbar spine imaging.
abstract: The purpose of our study was to evaluate the accuracy of MR myelography in depicting disc herniation in the lumbar spine when compared with conventional MRI in patients presenting with clinical evidence of disc herniation. One hundred patients referred for conventional MR imaging of the lumbar spine also had coronal MR (TR 9000 ms, TE 272 ms eff, NEX 3, echo train length 32) myelography performed. Three experienced observers compared magnetic resonance myelography (MRM) with conventional lumbar spine MR using the following variables: visibility of thecal sac and nerve roots, and the presence, location and severity of disc herniation. Disc protrusions were seen at 110 disc space levels on conventional MR images as opposed to 93 on MRM. However, only 72 % of lesions seen on conventional MR were diagnosed by MRM. Similarly, only 63.8 % of nerve root compression abnormalities seen at conventional MR were visualized when compared with conventional MRM. The sensitivity, specificity and accuracy of MRM when compared with conventional MR was 72, 93 and 85 %, respectively. The MRM technique yields images that resemble conventional myelography and may be used to help confirm abnormalities seen on conventional MR in selected cases; however, the large number of false-positive and false-negative examinations indicates that caution should be used in interpreting MRM images.
authors.affiliation: Department of Radiology, Beaumont Hospital, P. O. Box 1297, Dublin 9, Ireland.
authors.forename: M J
authors.initials: MJ
authors.lastname: Thornton
authors.forename: M J
authors.initials: MJ
authors.lastname: Lee
authors.forename: S
authors.initials: S
authors.lastname: Pender
authors.forename: F P
authors.initials: FP
authors.lastname: McGrath
authors.forename: R P
authors.initials: RP
authors.lastname: Brennan
authors.forename: J C
authors.initials: JC
authors.lastname: Varghese
mesh_terms: D006801:Humans; D007403:Intervertebral Disc / Q000473:pathology; D007405:Intervertebral Disc Displacement / Q000175:diagnosis*; D008159:Lumbar Vertebrae / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D012680:Sensitivity and Specificity; D013116:Spinal Cord / Q000473:pathology*; D013126:Spinal Nerve Roots / Q000473:pathology