Transcription factors for lens development assessed in vivo.
Lens-cell differentiation occurs at a fairly early stage of embryogenesis and results in very simple tissue architecture. These features allow the embryonic lens to provide a paradigm of tissue development starting from tissue induction to tissue maturation. Not only have a number of transcription factors participating in lens development been identified but their actual functions are now assessed by modern approaches utilizing genetic and tissue manipulations of embryos.
Kondoh
H
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Institute for Molecular and Cellular Biology Osaka University 1-3 Yamadaoka, Suita, Osaka, Japan. j61056@center.osaka-u.ac.jp
D000818:Animals; D002451:Cell Compartmentation; D002454:Cell Differentiation / Q000502:physiology; D005314:Embryonic and Fetal Development / Q000235:genetics / Q000502:physiology; D007908:Lens, Crystalline / Q000166:cytology / Q000196:embryology*; D014157:Transcription Factors / Q000502:physiology*
D014157:Transcription Factors