title: Synthesis and antibacterial activity of 2-aryl-2,5-dihydro-3(3H)-oxo-pyridazino[4,3-b]indole-4-carboxylic acids.
abstract: The in vitro antibacterial and antifungal activities of a series of pyridazinoindolonic acids II against some selected representative of Gram-positive, Gram-negative bacteria and fungi have been investigated. Some interesting observations among the structural features necessary for high antibacterial activity are presented and discussed.
authors.affiliation: Dipartimento Farmacochimico, Università di Bari, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Palluotto
authors.forename: A
authors.initials: A
authors.lastname: Carotti
authors.forename: G
authors.initials: G
authors.lastname: Casini
authors.forename: M
authors.initials: M
authors.lastname: Ferappi
authors.forename: A
authors.initials: A
authors.lastname: Rosato
authors.forename: C
authors.initials: C
authors.lastname: Vitali
authors.forename: F
authors.initials: F
authors.lastname: Campagna
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D007211:Indoles / Q000138:chemical synthesis / Q000494:pharmacology*; D015394:Molecular Structure; D011724:Pyridazines / Q000138:chemical synthesis / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D007211:Indoles; D011724:Pyridazines