title: [A computerized multivariate analysis in the assessment of the prognosis of breast cancer after surgical excision].
abstract: BACKGROUND
  The prognostic parameters most universally accepted as indicative for the assessment of 5 and 10 year survival in breast cancer are considered.
  
  
  METHODS
  The aims of this study were to elucidate the relationships among these parameters and to determine the specific interrelations of these prognostic factors. These parameters (age, grading, tumour size, lymphatic and vascular invasion, necrosis, lymph node status and number of nodes positive) are analysed by univariate and multivariate analysis on a series of 75 patients.
  
  
  RESULTS
  The analysis performed confirms prognostic accuracy of age, tumor size, number of nodes positive (p < 0.05, p < 0.001, p < 0.003, respectively) when considered singularly but the impossibility of deriving any benefit from the study of their reciprocal interrelations.
  
  
  CONCLUSIONS
  This is due to the importance of each parameter assumes independently from the other and to the reciprocal compensation that occurs when all possible interactions are considered.
authors.affiliation: Cattedra di Chirurgia Generale, Università degli Studi, Tor Vergata, Roma.
authors.forename: C
authors.initials: C
authors.lastname: Spina
authors.forename: F
authors.initials: F
authors.lastname: Russo
authors.forename: P
authors.initials: P
authors.lastname: D'Antini
authors.forename: G
authors.initials: G
authors.lastname: Coscarella
authors.forename: M
authors.initials: M
authors.lastname: Grande
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D016014:Linear Models; D008207:Lymphatic Metastasis; D008875:Middle Aged; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D011379:Prognosis; D016019:Survival Analysis
vernacular_title: Analisi multivariata computerizzata nella valutazione della prognosi del cancro della mammella dopo exeresi chirurgica.