title: Microbial metabolism of artemisitene.
abstract: Studies on the microbial transformation of the sesquiterpene endoperoxide artemisitene have revealed that artemisitene was metabolized by Aspergillus niger (NRRL 599) to yield 11-epi-artemisinin, 9 beta-hydroxydeoxy-11-epi-artemisinin and 9 beta-hydroxy-11-epi-artemisinnin. These metabolites were characterized on the basis of their spectral data.
authors.affiliation: Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. kyorabi@ksu.edu.sa
authors.forename: K Y
authors.initials: KY
authors.lastname: Orabi
authors.forename: A M
authors.initials: AM
authors.lastname: Galal
authors.forename: A R
authors.initials: AR
authors.lastname: Ibrahim
authors.forename: F S
authors.initials: FS
authors.lastname: el-Feraly
authors.forename: S I
authors.initials: SI
authors.lastname: Khalifa
authors.forename: H N
authors.initials: HN
authors.lastname: el-Sohly
mesh_terms: D037621:Artemisinins; D001234:Aspergillus niger / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000378:metabolism*
chemical_list: D037621:Artemisinins; D012717:Sesquiterpenes; C105118:artemisitene