title: [Exercise tolerance of patients under nasal intermittent positive pressure ventilation (nIPPV)].
abstract: BACKGROUND
  There are only a few papers concerning with exercise tolerance of patients under nasal intermittent positive pressure ventilation (nIPPV).
  
  
  METHODS
  Therefore since 1996 we routinely checked exercise tolerance of our nIPPV-patients when admitted to the hospital. Till March 1997 we had carried out 1386-minute walking tests (6-min WT) in 111 patients.
  
  
  OBJECTIVE
  Is there an improvement of exercise tolerance in the course of nIPPV-therapy? Are hypoxemia or hypercapnia occurring during exercise-test?
  
  
  METHODS
  The 6-min WT was performed after one practice walk. The patients got oxygen in case of a preexisting oxygen therapy or in case of an oxygen saturation below 85% before starting. Blood gas analyses were carried out before and after stopping the test. Oxygen saturation and heart rate were registered continuously. The distance walked was measured. Twenty-one patients were tested before introducing nIPPV therapy and 3 months after home mechanical ventilation (HMV).
  
  
  RESULTS
  The average distance walked amounted only 283 +/- 82 m (norm in healthy persons: 800 m). pO2 decreased from 69 +/- 11 to 58 +/- 12 mm Hg, pCO2 increased from 47 +/- 8 to 49 +/- 8 mm Hg. Oxygen saturation (SaO2) fell from 92 +/- 5 to 80 +/- 10%, heart rate increased from 104 +/- 18 to 130 +/- 23 beats/min. The distance walked changed not significantly from 282 +/- 109 to 308 +/- 71 m. Six patients could be tested a 3rd time after 6 months HMV. The distance walked was 315 +/- 103 m (also no significant difference).
  
  
  CONCLUSIONS
  Everyday activity can cause severe hypoxemia in nIPPV patients. Ambulatory oxygen therapy should be considered in each case. A significant improvement of exercise tolerance under nIPPV therapy is not yet proven. Our data only show a tendency towards an increase.
authors.affiliation: Zentralkrankenhaus Gauting der LVA Oberbayern, Gauting.
authors.forename: F
authors.initials: F
authors.lastname: Bullemer
authors.forename: P
authors.initials: P
authors.lastname: Kroworsch
authors.forename: S
authors.initials: S
authors.lastname: Heindl
authors.forename: S
authors.initials: S
authors.lastname: Winkler-Wehgartner
authors.forename: O
authors.initials: O
authors.lastname: Karg
mesh_terms: D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D006701:Home Nursing / Q000379:methods; D006801:Humans; D007385:Intermittent Positive-Pressure Ventilation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009666:Nose
vernacular_title: Körperliche Belastbarkeit von Patienten mit Atempumpenschwäche unter intermittierender Selbstbeatmung.