[Application of the principles of the systemic approach to interpretation of the pathogenesis of traumatic shock and traumatic disease].
Experimental and clinical studies for many years led the authors to the conclusion that systemic approach seems most adequate for current interpretation of pathogenesis of traumatic disease (TD) and its component--traumatic shock (TS). It seems valid to assess TD and TS severity and dynamics by the proportion of pathological and adaptive reactions. Drugs should be used for maintenance and stimulation of adaptive reactions. Strong correlations of dynamics and severity of TD and TS enable prediction of TD course and outcome in acute period by time criterion (+)-T and distinguish three degrees of TD severity as well as evaluation of probability of favorable or unfavorable (lethal) outcome.
Seleznev
S A
SA
Shapot
Iu B
IuB
D000222:Adaptation, Physiological; D006801:Humans; D012189:Retrospective Studies; D012774:Shock, Traumatic / Q000209:etiology*; D014947:Wounds and Injuries / Q000209:etiology*
Prilozhenie printsipov sistemnogo podkhoda k traktovke patogeneza travmaticheskogo shoka i travmaticheskoĭ bolezni.