title: Behavioural context and a distributed system: metabolic mapping studies of the basal ganglia.
abstract: Behavioural context is known to affect neural activity in the striatum. Responses of single cells increase to rewarding stimuli, or drop out as a bar press or saccade is learned. Networks that can accomplish a unique response to changing contexts are of particular interest to systems neuroscience and were a part of Hebb's interest in perception and learning. An overall map of the striatum that localizes changes related to this remarkable phenomenon of contextual responses contributes to our understanding of anatomical substrates of neural systems that integrate information, and may lead us to new striatal regions to study synaptic mechanisms of learning.
authors.affiliation: Institute for Basic Research in Developmental Disabilities, USA.
authors.forename: T I
authors.initials: TI
authors.lastname: Lidsky
authors.forename: L L
authors.initials: LL
authors.lastname: Brown
mesh_terms: D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D001479:Basal Ganglia / Q000033:anatomy & histology / Q000502:physiology*; D001931:Brain Mapping; D007858:Learning / Q000502:physiology*; D008297:Male; D009474:Neurons / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013003:Somatosensory Cortex / Q000502:physiology; D014110:Touch / Q000502:physiology*