title: [A study of peripheral neural conduction, motor and sensory, in diabetic patients treated with hyperbaric oxygenation].
abstract: BACKGROUND
  There are some occlusive disorders in the vasa nervorum and metabolic changes disminishing oxygen liberation by erytrocites at the capillary blood vessels, and these disturbances lead to endoneural microhypoxia. Hyperbaric oxygen reverts hypoxia in the diabetic neuropathy.
  
  
  OBJECTIVE
  We studied motor and sensitive peripheric neuroconduction in nine diabetic patients, with distal symmetrical polyneuropathy, during normoglycemia. Four of them were insulin dependent and five were non insulin dependent.
  
  
  METHODS
  The electrophysiological studies were done before treatment with hyperbaric oxygen, in a week, three and six months later. The abnormal electrophysiological parameters detected in diabetics were terminal latencies (enlarged), velocities of conduction (slowed) and distal amplitudes of compound action potentials (reduced).
  
  
  RESULTS
  Neither distal latencies nor distal amplitudes and conduction velocities in peroneal nerve showed significative changes in the statistical analysis. We observed slower conduction velocities in the motor fibers of the median nerve in the examination performed six months after treatment. There was an increase of distal latency and retardation of the velocity of conduction six months later after treatment in the sensitive fibers of median nerve, whereas the amplitudes of sensitive action potentials decreased progressively. These changes suggest large diameter peripheral fibers didn't receive benefit with hyperbaric oxygen treatment.
  
  
  CONCLUSIONS
  In all patients disappeared all symptoms of dysesthesias, paresthesias, distal pains and cramps in the legs and arms, suggesting functional changes in small unmyelinated fibers which we can't test with conventional techniques to prove it.
authors.affiliation: Departamento de Neurofisiología Clínica, Hospital Clínico Quirúrgico Hermanos Ameijeiras, La Habana, Cuba.
authors.forename: C
authors.initials: C
authors.lastname: Viera
authors.forename: C
authors.initials: C
authors.lastname: Gálvez
authors.forename: B
authors.initials: B
authors.lastname: Carrasco
authors.forename: C
authors.initials: C
authors.lastname: Santos
authors.forename: R
authors.initials: R
authors.lastname: Castellanos
mesh_terms: D000328:Adult; D003929:Diabetic Neuropathies / Q000150:complications / Q000628:therapy*; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods*; D008297:Male; D008475:Median Nerve / Q000502:physiology*; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology*; D009120:Muscle Cramp / Q000209:etiology; D009412:Nerve Fibers / Q000502:physiology; D009431:Neural Conduction / Q000502:physiology*; D009475:Neurons, Afferent / Q000502:physiology*; D010292:Paresthesia / Q000209:etiology; D016896:Treatment Outcome
vernacular_title: Estudio de la neuroconducción periférica, motora y sensitiva en pacientes diabéticos tratados con oxigenación hiperbárica.