Histopathological changes after induced injury in leeches.
Cells involved in leech inflammatory responses have been characterized by morphological, histochemical, and immunohistochemical methods. Macrophage-like cells, NK-like cells, and granulocytes migrated shortly after injury by pricking with bacterial lipopolysaccharide. Inflammatory responses increased progressively and provoked cell migration to the body wall and then to wound surfaces. Macrophages, NK cells, and granulocytes display similar features and behavior traits in invertebrates and vertebrates.
de Eguileor
M
M
DBSF, University of Insubria, Via J. H. Dunant 3, Varese, 21100, Italy.
Tettamanti
G
G
Grimaldi
A
A
Boselli
A
A
Scarì
G
G
Valvassori
R
R
Cooper
E L
EL
Lanzavecchia
G
G
D000818:Animals; D002465:Cell Movement; D006098:Granulocytes / Q000502:physiology; D006651:Histocytochemistry; D007249:Inflammation / Q000473:pathology*; D007694:Killer Cells, Natural / Q000502:physiology; D007865:Leeches; D008264:Macrophages / Q000502:physiology; D014945:Wound Healing / Q000502:physiology*