title: Auricular carcinoma with temporal bone invasion: outcome analysis.
abstract: Invasion of the temporal bone by cutaneous carcinoma of the auricle and periauricular skin is an ominous prognostic sign. Management includes aggressive resection of cutaneous disease as well as resection of temporal bone to obtain a medial margin. Analysis of data from 21 patients with temporal bone invasion caused by cutaneous malignancy is presented. Overall survival is approximately 63%. Cumulative survival is significantly decreased in patients with squamous cell carcinoma when compared with other invasive malignancies. Univariate and covariate analyses demonstrate that nodal status, positive microscopic soft tissue margins, and persistent perineural disease at the skull base did not significantly affect survival in this series. There is a trend toward increased survival in patients receiving postoperative radiation in this series.
authors.affiliation: Division of Otolaryngology, University of South Florida College of Medicine, Tampa 33612, USA.
authors.forename: T J
authors.initials: TJ
authors.lastname: Gal
authors.forename: N D
authors.initials: ND
authors.lastname: Futran
authors.forename: L J
authors.initials: LJ
authors.lastname: Bartels
authors.forename: D W
authors.initials: DW
authors.lastname: Klotch
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000473:pathology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D004428:Ear Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011379:Prognosis; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D013701:Temporal Bone / Q000473:pathology* / Q000601:surgery