title: [Myelopeptides as a new group of regulatory peptides].
abstract: The paper summarizes the data available on the structural and functional characteristics of the brain marrow immunoregulatory peptides myelopeptides (MPs). It describes the amino acid sequences of 6 individual MPs, their biological properties and mechanism. MP-1 is a hexapeptide having an immunocorrective effect. MP-2 has antitumor action, MP-3 stimulates the phagocytic activity of macrophages, M-4 is a new differentiating factor. The endogenous origin of the MPs isolated, their structure, and the pattern of their biological effects lead to the conclusion that MPs represent a new group of regulatory peptides that are promising for clinical application.
authors.forename: A A
authors.initials: AA
authors.lastname: Mikhaĭlova
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000276:immunology*; D002455:Cell Division / Q000187:drug effects; D006801:Humans; D007155:Immunologic Factors / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D009842:Oligopeptides / Q000737:chemistry / Q000494:pharmacology
chemical_list: D007155:Immunologic Factors; D009842:Oligopeptides; C048617:myelopeptides
vernacular_title: Mielopeptidy - novaia gruppa reguliatornykh peptidov.