title: Biological and chemical characterization of the fraction with antiherpetic activity from Achyrocline flaccida.
abstract: The in vitro antiviral activity demonstrated by aqueous extract (AE) of Achyrocline flaccida on herpes simplex virus type-1 is exerted early during the viral replication, essentially during the viral adsorption to host cells. A bioguided purification process of the AE indicated that negatively charged polysaccharides were responsible for this antiviral activity.
authors.affiliation: Cátedra de Virología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
authors.forename: G
authors.initials: G
authors.lastname: García
authors.forename: L
authors.initials: L
authors.lastname: Cavallaro
authors.forename: A
authors.initials: A
authors.lastname: Broussalis
authors.forename: G
authors.initials: G
authors.lastname: Ferraro
authors.forename: V
authors.initials: V
authors.lastname: Martino
authors.forename: R
authors.initials: R
authors.lastname: Campos
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D019659:Asteraceae / Q000737:chemistry*; D002522:Chlorocebus aethiops; D018259:Herpesvirus 1, Human / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D014709:Vero Cells
chemical_list: D000998:Antiviral Agents; D010936:Plant Extracts