title: Hypoglycaemic response to Zygophyllum gaetulum extracts in patients with non-insulin-dependent diabetes mellitus.
abstract: Zygophyllum gaetulum leaves are one of several traditional remedies used for diabetes treatment in Morocco. Its ability to lower the blood glucose was studied in 13 patients with non-insulin-dependent diabetes mellitus. The reaction time of the Z. gaetulum aqueous extract at a single oral dose (440 mg/kg) producing a significant hypoglycaemic effect is 6 h after administration. The same dose ingested twice daily resulted in a significant reduction of blood glucose during the first week, and maintained the patient in normoglycaemia throughout the 2 week course of treatment, with no change in body weight.
authors.affiliation: Department of Biology, High School of Education, Marrakesh, Morocco.
authors.forename: J T
authors.initials: JT
authors.lastname: Jaouhari
authors.forename: H B
authors.initials: HB
authors.lastname: Lazrek
authors.forename: A
authors.initials: A
authors.lastname: Seddik
authors.forename: M
authors.initials: M
authors.lastname: Jana
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D001786:Blood Glucose / Q000187:drug effects*; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009018:Morocco; D010936:Plant Extracts / Q000009:adverse effects / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D010936:Plant Extracts