title: Poor reproducibility of false-positive tilt testing results in healthy volunteers.
abstract: Positive responses to head-up tilt testing occur in healthy subjects. However, the reproducibility of "false-positive" tilt testing results has not been clarified. To study the reproducibility of "false-positive" responses, we prospectively performed 2 tilt tests separated by 1 to 10 (mean 3.2) weeks in 20 healthy males aged 23 to 40 years (mean 30 years). The baseline tilt test (80 degrees for 30 minutes) ended positive in 4 (20%) subjects on the initial test and 2 (10%) on the second test with only 1 (5%) who had consecutive positive responses. No additional positive responses were noted during the isoproterenol (0.01 microgram/kg/min)-tilt test for 10 minutes. We demonstrated that a false-positive response occurred in 5 (25%) of 20 young males who underwent 2 tilt tests, however, only 1 (5%) subject had consecutive positive responses. Poor reproducibility may be characteristic of false-positive responses in head-up tilt testing.
authors.affiliation: Department of Cardiology, Juntendo University Izunagaoka Hospital, Shizuoka, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Sumiyoshi
authors.forename: Y
authors.initials: Y
authors.lastname: Mineda
authors.forename: S
authors.initials: S
authors.lastname: Kojima
authors.forename: S
authors.initials: S
authors.lastname: Suwa
authors.forename: Y
authors.initials: Y
authors.lastname: Nakata
mesh_terms: D000328:Adult; D001794:Blood Pressure; D005189:False Positive Reactions; D006339:Heart Rate; D006801:Humans; D008297:Male; D011187:Posture; D011446:Prospective Studies; D015203:Reproducibility of Results; D013575:Syncope / Q000175:diagnosis*