title: Turn up the HEAT.
abstract: The recently determined crystal structure of the PR65/A subunit of protein phosphatase 2A reveals the architecture of proteins containing HEAT repeats. The structural properties of this solenoid protein explain many functional characteristics and account for the involvement of solenoids as scaffold, anchoring and adaptor proteins.
authors.affiliation: Structural Biology Laboratory, St Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia. B.Kobe@medicine.unimelb.edu.au
authors.forename: B
authors.initials: B
authors.lastname: Kobe
authors.forename: T
authors.initials: T
authors.lastname: Gleichmann
authors.forename: J
authors.initials: J
authors.lastname: Horne
authors.forename: I G
authors.initials: IG
authors.lastname: Jennings
authors.forename: P D
authors.initials: PD
authors.lastname: Scotney
authors.forename: T
authors.initials: T
authors.lastname: Teh
mesh_terms: D010749:Phosphoprotein Phosphatases / Q000737:chemistry*; D011487:Protein Conformation; D054648:Protein Phosphatase 2
chemical_list: D010749:Phosphoprotein Phosphatases; D054648:Protein Phosphatase 2