[Effect of beta-carotene oil and bee pollen on ion transport in rat brain slices following radiation-chemical exposure].
Chronic combined exposure to ionizing radiation with dose of 0.25 Gy and cadmium chloride or atrazine to be present in drinking water at five-fold Limited Permissible Concentration (LPC) values led to the additively reduced intercellular K+ level in rat brain, that was at first choice caused by the active ion transport disorders in the case of irradiation, and by the changes in membrane permeability in the case of toxic loading. Applying of beta-carotene oil and bee pollen both abolished radiation effects, but no chemical toxicant ones. Authors supposed the selective action of the observed drugs to be connected with antioxidant activities of them.
Anan'eva
T V
TV
Research Institute of Biology, Dnepropetrovsk University, Ukraine.
Dvoretskiĭ
A I
AI
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001280:Atrazine / Q000633:toxicity*; D001516:Bees; D001921:Brain / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D019256:Cadmium Chloride / Q000633:toxicity; D006540:Herbicides / Q000633:toxicity*; D017136:Ion Transport / Q000187:drug effects* / Q000528:radiation effects; D008297:Male; D011058:Pollen; D011188:Potassium / Q000378:metabolism*; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D019207:beta Carotene / Q000494:pharmacology*
D000975:Antioxidants; D006540:Herbicides; D011837:Radiation-Protective Agents; D019207:beta Carotene; D019256:Cadmium Chloride; D001280:Atrazine; D011188:Potassium
Effekty beta-karotinovogo masla i pchelinoĭ obnozhki pri radiatsionno-khimicheskom vozdeĭstvii na ionnyĭ transport v srezakh mozga krys.