Differential inhibition of chromatic and achromatic perception by transcranial magnetic stimulation of the human visual cortex.
The magnocellular visual pathway is devoted to low-contrast achromatic and motion perception whereas the parvocellular pathway deals with chromatic and high resolution spatial vision. To specifically separate perception mediated by these pathways we have used low-contrast Gaussian filtered black-white or coloured visual stimuli. By use of transcranial magnetic stimulation (TMS) over the visual cortex inhibition of magnocellular stimuli was achieved distinctly earlier by about 40 ms compared with parvocellular information. A nonspecific inhibition of all stimuli could be seen peaking at 75-90 ms, significantly higher for magnocellular stimuli. The particular vulnerability of magnocellular stimuli to TMS is correlated with distinct physiological properties of this pathway such as faster conduction velocity and non-linear stimulus encoding.
Paulus
W
W
Department of Clinical Neurophysiology, University of Göttingen, Germany.
Korinth
S
S
Wischer
S
S
Tergau
F
F
D000704:Analysis of Variance; D003118:Color Perception; D006801:Humans; D009431:Neural Conduction; D011930:Reaction Time; D050781:Transcranial Magnetic Stimulation; D014793:Visual Cortex / Q000502:physiology* / Q000528:radiation effects; D014795:Visual Pathways / Q000502:physiology; D014796:Visual Perception