title: Three molecular mechanisms to explain some biological effects of electromagnetic fields and hypogravity.
abstract: There are many reports about the biological effects of electromagnetic fields and hypogravity and there have been many attempts to develop a theoretical explanation of this phenomenon. In this work, a mechanism is described based on the action of these physical environmental factors on single electrically charged groups from amino acids and considering the elongation stage of the protein synthesis as one of the main targets for both factors. For some rapid bioeffects after short exposures, a direct action on the conformation of the binding site of proteins is postulated. The other mechanism described here is based on the effect of these factors on the motion of the ionized calcium at the extracellular fluid. Many reports about the influences of electromagnetic and gravitational fields on gene expression, enzyme activity, bone mineralization, and oncogenesis are discussed, taking into account the new molecular mechanisms.
authors.affiliation: Laboratorio Clínico, Hospital Universitario, Matanzas, Cuba.
authors.forename: R G
authors.initials: RG
authors.lastname: Menéndez
mesh_terms: D000818:Animals; D004574:Electromagnetic Fields; D005786:Gene Expression Regulation / Q000528:radiation effects; D006801:Humans; D018472:Hypogravity; D008954:Models, Biological; D009369:Neoplasms / Q000209:etiology / Q000503:physiopathology*; D009857:Oncogenes; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry / Q000528:radiation effects
chemical_list: D011506:Proteins