Transient pulmonary infiltrates during treatment with anti-thymocyte globulin.
We report the case of a 54-year-old woman with aplastic anemia, who developed transient pulmonary infiltrates following intravenous infusion of rabbit antithymocyte globulin (ATG) for 3 days. There was no other explanation than the infusion of ATG for the infiltrates. Rechallenge with ATG induced the recurrence of opacities on the chest radiograph. Although rarely involved with only 4 previous reports, ATG should be included in the list of drugs capable of inducing pulmonary infiltrates.
Maillard
N
N
Department/Division of Clinical Haematology, University Medical Center and Université de Bourgogne, Dijon, France.
Foucher
P
P
Caillot
D
D
Durand
C
C
Sgro
C
C
Camus
P
P
D000741:Anemia, Aplastic / Q000628:therapy*; D000818:Animals; D000961:Antilymphocyte Serum / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging* / Q000187:drug effects*; D008875:Middle Aged; D011817:Rabbits; D013902:Radiography, Thoracic; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D000961:Antilymphocyte Serum