title: Screening oocytes and preimplantation embryos for aneuploidy.
abstract: Pregnancy and live birth rates following in-vitro fertilization decline rapidly with advancing maternal age partly because of an increase in age-related aneuploidies occurring in female meiosis. Screening oocytes or preimplantation embryos for common aneuploidies is now possible by polar body or cleavage stage biopsy and multicolour fluorescence in-situ hybridization.
authors.affiliation: Centre for Preimplantation Genetic Diagnosis, Department of Obstetrics and Gynaecology, Guy's, King's College and St Thomas Hospitals School of Medicine, King's College London, UK.
authors.forename: A H
authors.initials: AH
authors.lastname: Handyside
authors.forename: C M
authors.initials: CM
authors.lastname: Ogilvie
mesh_terms: D000782:Aneuploidy; D001755:Blastocyst; D005260:Female; D006801:Humans; D009865:Oocytes; D011247:Pregnancy; D019836:Preimplantation Diagnosis