title: Arthritis of the finger joints: a comprehensive approach comparing conventional radiography, scintigraphy, ultrasound, and contrast-enhanced magnetic resonance imaging.
abstract: OBJECTIVE
  A prospective study was performed comparing conventional radiography, 3-phase bone scintigraphy, ultrasound, and magnetic resonance imaging (MRI) with precontrast and dynamic postcontrast examinations in 60 patients with various forms of arthritis including rheumatoid arthritis (RA), spondyl-arthropathy, and arthritis associated with connective tissue disease.
  
  
  METHODS
  A total of 840 finger joints were examined clinically and by all 4 imaging methods. Experienced investigators blinded to the clinical findings and diagnoses analyzed all methods independently of each other. The patients were divided into 2 groups. Group 1 included 32 patients (448 finger joints) without radiologic signs of destructive arthritis (Larsen grades 0-1) of the evaluated hand and wrist and group 2 included 28 patients (392 finger joints) with radiographs revealing erosions (Larsen grade 2) of the evaluated hand and/or wrist.
  
  
  RESULTS
  Clinical evaluation, scintigraphy, MRI, and ultrasound were each more sensitive than conventional radiography in detecting inflammatory soft tissue lesions as well as destructive joint processes in arthritis patients in group 1. All differences were statistically significant. We found ultrasound to be even more sensitive than MRI in the detection of synovitis. MRI detected erosions in 92 finger joints (20%; 26 patients) in group 1 that had not been detected by conventional radiography.
  
  
  CONCLUSIONS
  Our data indicate that MRI and ultrasound are valuable diagnostic methods in patients with arthritis who have normal findings on radiologic evaluation.
authors.affiliation: Department of Rheumatology and Clinical Immunology, Charité University Hospital, Humboldt University of Berlin, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Backhaus
authors.forename: T
authors.initials: T
authors.lastname: Kamradt
authors.forename: D
authors.initials: D
authors.lastname: Sandrock
authors.forename: D
authors.initials: D
authors.lastname: Loreck
authors.forename: J
authors.initials: J
authors.lastname: Fritz
authors.forename: K J
authors.initials: KJ
authors.lastname: Wolf
authors.forename: H
authors.initials: H
authors.lastname: Raber
authors.forename: B
authors.initials: B
authors.lastname: Hamm
authors.forename: G R
authors.initials: GR
authors.lastname: Burmester
authors.forename: M
authors.initials: M
authors.lastname: Bollow
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000175:diagnosis*; D001175:Arthrography; D003240:Connective Tissue Diseases / Q000150:complications / Q000175:diagnosis; D003287:Contrast Media; D005069:Evaluation Studies as Topic; D005260:Female; D005384:Finger Joint / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011877:Radionuclide Imaging; D013167:Spondylitis, Ankylosing / Q000175:diagnosis; D014463:Ultrasonography
chemical_list: D003287:Contrast Media