title: Ultrasound-guided percutaneous transthoracic needle aspiration biopsy for diagnosis of pulmonary lesions in advanced HIV infection.
abstract: Pulmonary diseases remain the most common complication associated with high morbidity and mortality in patients with human immunodeficiency virus (HIV) infection. Invasive diagnostic procedures are often needed to establish a specific diagnosis of pulmonary disease. We report our experience with ultrasound (US)-guided percutaneous transthoracic needle aspiration (PTNA) biopsy in 20 consecutive patients with advanced HIV infection who presented with a variety of pulmonary lesions with or without pleural effusion. A specific diagnosis was established in 16 patients (80%), with infection being the most common etiology. Sputum culture yielded the same causative pathogen in three patients (15%) and all had more than one bacterial or fungal isolates. Mild pneumothorax, the only complication, was observed in two patients (10%) following the procedure. Neither patient required chest tube drainage. Our findings suggest that US-guided PTNA can be a useful and safe alternative to fluoroscopy-guided PTNA in selected HIV-infected patients with focal pulmonary lesions and pleural effusion.
authors.affiliation: Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: C C
authors.initials: CC
authors.lastname: Hung
authors.forename: M Y
authors.initials: MY
authors.lastname: Chen
authors.forename: P H
authors.initials: PH
authors.lastname: Kuo
authors.forename: S M
authors.initials: SM
authors.lastname: Hsieh
authors.forename: W H
authors.initials: WH
authors.lastname: Sheng
authors.forename: P C
authors.initials: PC
authors.lastname: Yang
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000473:pathology; D000328:Adult; D001707:Biopsy, Needle / Q000379:methods*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008171:Lung Diseases / Q000209:etiology / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012514:Sarcoma, Kaposi / Q000473:pathology; D018084:Ultrasonography, Interventional