[Observation on oligodendroglioma with light, electron microscopy and immunohistochemistry].
OBJECTIVE
To investigate the ultrastructural and histological characteristics of oligodendroglioma (ODG).


METHODS
By means of light microscopy and partially electron microscopy and immunohistochemistry, 65 cases of ODG were observed.


RESULTS
According to WHO classification of the tumor, all 65 cases of ODG were graded in the degree of differentiation of tumor cells, showing 19 cases of Grade I, 32 cases of Grade II and 14 cases of Grade III.


CONCLUSIONS
(1) The presence of glial filaments in tumor cells may be explained as a heterogeneity in differentiation. (2) Besides the degree of differentiation, some other criteria such as cellular density and mitotic activity are also closely related to the grading of ODG.
Hang
Z
Z
Department of Pathology, West China University of Medical Sciences, Chengdu.
Chen
D
D
Wei
Y
Y
D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009837:Oligodendroglioma / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D016708:Synaptophysin / Q000032:analysis
D005904:Glial Fibrillary Acidic Protein; D016708:Synaptophysin