title: [Positivity rate of TTV-DNA in patients with acute liver injury of undetermined etiology].
abstract: To elucidate a role of TTV infection in patients with acute liver injury, TTV-DNA in the sera from 97 patients with acute liver injury of various etiology were determined according to Okamoto's method. Out of 77 patients with acute liver injury of determined etiology, 31 patients(40.3%) showed TTV-DNA positive, and out of 15 patients with acute liver injury of undetermined etiology, 8 patients(53.3%) showed TTV-DNA positive. These results suggested no evident role of TTV in patients with acute liver injury was shown. Further study including genotype and quantitative determination of TTV-DNA and antibody assay is needed.
authors.affiliation: 2nd Department of Internal Medicine, Dokkyo University School of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Murohisa
authors.forename: H
authors.initials: H
authors.lastname: Sugaya
authors.forename: S
authors.initials: S
authors.lastname: Asai
authors.forename: O
authors.initials: O
authors.lastname: Suzuki
authors.forename: M
authors.initials: M
authors.lastname: Tamano
authors.forename: M
authors.initials: M
authors.lastname: Oguma
authors.forename: M
authors.initials: M
authors.lastname: Iijima
authors.forename: N
authors.initials: N
authors.lastname: Yanagisawa
authors.forename: A
authors.initials: A
authors.lastname: Terano
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D015415:Biomarkers / Q000032:analysis; D004266:DNA Virus Infections / Q000150:complications / Q000453:epidemiology / Q000821:virology*; D004267:DNA Viruses / Q000235:genetics / Q000302:isolation & purification*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006525:Hepatitis, Viral, Human / Q000150:complications / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D008107:Liver Diseases / Q000150:complications / Q000821:virology*; D008297:Male; D008875:Middle Aged
chemical_list: D015415:Biomarkers; D004279:DNA, Viral