title: Hydrogen tunneling in biology.
abstract: The mechanistic details of hydrogen transfer in biological systems are not fully understood. The traditional approach has been to use semiclassical transition-state theory. This theory cannot explain many experimental findings, however, so different approaches that emphasize the importance of quantum mechanics and dynamic effects should also be considered.
authors.affiliation: Departments of Chemistry and Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.
authors.forename: A
authors.initials: A
authors.lastname: Kohen
authors.forename: J P
authors.initials: JP
authors.lastname: Klinman
mesh_terms: D002384:Catalysis; D004798:Enzymes; D006859:Hydrogen; D007700:Kinetics; D008956:Models, Chemical; D014732:Vibration
chemical_list: D004798:Enzymes; D006859:Hydrogen