title: Spectral studies on the interaction of DNA and Ru(bipy)2(dppx)2+.
abstract: The interaction of Ru(bipy)2(dppx)2+ (bipy = 2.2'-bipyridine,dppx = 7,8-dimethyldipyrido phenazine) with the calfthymus DNA has been studied with fluorescence and ultraviolet visible absorption spectroscopy. The results of fluorescence quenching and salt effect show that Ru(bipy)2(dppx)2+ intercalate into the double helix of DNA. The ultraviolet visible absorption spectrum of Ru(bipy)2(dppx)2+, calfthymus DNA, and their interaction indicate that Ru(bipy)2(dppx)2+ intercalate into the double helix of DNA via the ligand dppx.
authors.forename: L S
authors.initials: LS
authors.lastname: Ling
authors.forename: Z K
authors.initials: ZK
authors.lastname: He
authors.forename: Y E
authors.initials: YE
authors.lastname: Zeng
mesh_terms: D000042:Absorption; D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D005453:Fluorescence; D009942:Organometallic Compounds / Q000737:chemistry* / Q000378:metabolism; D009994:Osmolar Concentration; D012428:Ruthenium / Q000737:chemistry / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet / Q000379:methods
chemical_list: D009942:Organometallic Compounds; D012428:Ruthenium; D004247:DNA