title: Association of edentulousness with systemic factors in elderly people living at home.
abstract: OBJECTIVE
  To examine the association of edentulousness with systemic factors: age, gender, tobacco-smoking, alcohol intake, body mass index, functioning in daily living, cortical thickness at the mandibular angle, and systemic diseases: bone-fracture (an indicator for osteoporosis), diabetes, thyroid disease, hyperparathyroidism, asthma, heart failure, hypertension.
  
  
  METHODS
  The study population comprised 293 elderly subjects, 124 (42%) edentulous and 169 (58%) dentate. The data from clinical and radiographic examinations and structured interviews were analyzed by multiple logistic regression.
  
  
  RESULTS
  When edentulousness in both the mandible and the maxilla was considered, history of bone fracture and tobacco-smoking were significantly related to complete edentulousness with odds ratios (OR) of 2.51 (95% CI: 1.47-4.28) and 2.42 (95% CI: 1.32-4.43) respectively, associations independent of age and gender. A similar association was found for the edentulous mandible. In the elderly subjects with an edentulous maxilla, besides the significant factors of history of bone fracture and tobacco-smoking, asthma was also associated with edentulousness at an odds ratio of 10.81 (95% CI: 1.38-84.66), oldest subjects most often being edentulous (OR: 2.23, 95% CI: 1.13-4.39). Diabetes was not related to edentulousness either in the mandible or in the maxilla.
  
  
  CONCLUSIONS
  The finding of associations of history of bone fracture, tobacco-smoking, and asthma with edentulousness emphasizes the association of systemic conditions with edentulousness. Advanced age was related to an edentulous maxilla. The relationship between asthma and total tooth loss in the maxilla might suggest a local oral effect of medications used by asthmatic patients.
authors.affiliation: School of Stomatology, Beijing Medical University, People's Republic of China.
authors.forename: Q
authors.initials: Q
authors.lastname: Xie
authors.forename: A
authors.initials: A
authors.lastname: Ainamo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000150:complications; D001851:Bone Diseases, Metabolic / Q000150:complications / Q000453:epidemiology*; D016321:Dental Care for Aged / Q000706:statistics & numerical data*; D017742:Dental Care for Chronically Ill / Q000706:statistics & numerical data*; D005260:Female; D005387:Finland / Q000453:epidemiology; D050723:Fractures, Bone / Q000150:complications; D006801:Humans; D007575:Jaw, Edentulous / Q000453:epidemiology* / Q000209:etiology; D016015:Logistic Models; D008297:Male; D016017:Odds Ratio; D012907:Smoking / Q000009:adverse effects