The human herpesvirus-type 8 is not involved in malignant melanoma.
Malignant melanomas were supposed to harbour the human herpesvirus-type 8 (HHV-8) genome, as melanoma cells were reported to express interleukin-6 and a homologue of interleukin-6 was found in the HHV-8 genome. We therefore investigated 33 primary malignant melanomas by polymerase chain reaction, but could not find this tumorigenic gamma-herpesvirus in any tumour.
Deichmann
M
M
Universitäts-Hautklinik Heidelberg, Germany.
Thome
M
M
Bock
M
M
Jäckel
A
A
Waldmann
V
V
Näher
H
H
D004279:DNA, Viral / Q000302:isolation & purification; D019288:Herpesvirus 8, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D015850:Interleukin-6 / Q000235:genetics; D008545:Melanoma / Q000473:pathology / Q000821:virology*; D016133:Polymerase Chain Reaction
D004279:DNA, Viral; D015850:Interleukin-6