title: [Visceral leishmaniasis associated with Wegener disease. Use of lipid complex amphotericin B and liposomal amphotericin B].
abstract: BACKGROUND
  Leishmaniasis in a patient with Wegenerís disease raises the problem of amphotericin toxicity further compromising the pre-existing renal disorder.
  
  
  METHODS
  An anemic patient treated for Wegenerís disease developed visceral leishmaniasis. This renal failure patient was treated with lipid complex amphotericin B and liposomal amphotericin B. We report outcome at 10 months follow-up.
  
  
  CONCLUSIONS
  The new formulations of amphotericin B allow effective treatment of visceral leishmaniasis in renal failure patients. Long-lasting results are probably favored by the interruption of immuno-suppressive therapy.
authors.affiliation: Service de Médecine interne II, Hôpital de l'Archet I, Nice.
authors.forename: H
authors.initials: H
authors.lastname: Zanaldi
authors.forename: E
authors.initials: E
authors.lastname: Rosenthal
authors.forename: P
authors.initials: P
authors.lastname: Marty
authors.forename: R M
authors.initials: RM
authors.lastname: Chichmanian
authors.forename: A
authors.initials: A
authors.lastname: Pesce
authors.forename: J P
authors.initials: JP
authors.lastname: Cassuto
mesh_terms: D058186:Acute Kidney Injury / Q000188:drug therapy; D000368:Aged; D000666:Amphotericin B / Q000009:adverse effects / Q000627:therapeutic use*; D000740:Anemia / Q000188:drug therapy; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D014890:Granulomatosis with Polyangiitis / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000139:chemically induced*; D008081:Liposomes; D008297:Male; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D008081:Liposomes; D000666:Amphotericin B
vernacular_title: Leishmaniose viscérale associée à une maladie de Wegener. Utilisation de l'amphotéricine B en complexes lipidiques et de l'amphotéricine B liposomale.