[Long term evolution of the incapacity in schizophrenic patients in maintenance treatment with risperidone].
OBJECTIVE
To determine the evolution of the degree of long term disability (8 months) in a group of schizophrenic outpatients undergoing monotherapy with risperidone. DESIGN, An observational multicentre study of 8 months follow up.


METHODS
354 patients with schizophrenic disorder (ICD-10).


RESULTS
Baseline, 2, 4 and 8 months.


METHODS
BPRS, CGI, UKU, WHO/DAS-S.


RESULTS
a significant decrease in both the global scores and in each of the 4 areas of disability. Improvement in disability depends to a large degree on the improvement of the disorder as shown on the BPRS and CGI. After 8 months, those patients with paranoid subtype and the less severe ones (BPRS and CGI) showed a considerably lesser degree of disability. The final level of disability (square root = 0,61) is narrowly related to the baseline level of disability, the 3 clusters of the final BPRS, the final CGI, gender and the subtype of schizophrenia.
Bobes
J
J
Area de Psiquiatría,Universidad de Oviedo, Oviedo,Asturias, 33006,España.
González
M P
MP
Gibert
J
J
Gutiérrez
M
M
Herráiz
M L
ML
D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D004185:Disability Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D018967:Risperidone / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy*
D014150:Antipsychotic Agents; D018967:Risperidone
Evolución a largo plazo de la discapacidad en pacientes esquizofrénicos en tratamiento de mantenimiento con risperidona.