title: [Prevention and treatment of stroke after hypertension for ten years in Hunan Province].
abstract: In this single blind, randomized multiple center clinical trial, the patients care period was divided into two stages. In the first stage (1985, 1-1989, 12), 984 cases were observed for 5 years whereas in the second stage (1990, 1-1994, 12), 2080 cases were observed and were subdivided into two groups, treat group and control, both were followed up for 5 years. The results showed that the prevalence of hypertension increased gradually. In the second stage, the average of blood pressure of the treatment group, using nitrendipine, was lower than that of the control group. There was significant difference between the two groups (P < 0.05). In the treatment group, the stroke and death rates were also decreased significantly as compared with the control group and the first stage group (P < 0.01).
authors.affiliation: Department of Cardiovascular, Affiliated Xiangya Hospital of Human University, Changsha.
authors.forename: M
authors.initials: M
authors.lastname: Sun
authors.forename: H
authors.initials: H
authors.lastname: Zhou
authors.forename: Z
authors.initials: Z
authors.lastname: Jia
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D009568:Nitrendipine / Q000627:therapeutic use*; D016037:Single-Blind Method
chemical_list: D000959:Antihypertensive Agents; D009568:Nitrendipine