Pseudolymphoma syndrome due to carbamazepine.
We described a 29-year-old Japanese woman with a pseudolymphoma syndrome due to carbamazepine. Physical examination revealed a diffuse erythematous papular eruption over almost all of her body with generalized lymphadenopathy. Histopathologic examination disclosed histology compatible with the nodular pattern of pseudo-T-cell lymphoma. The Southern blot analysis did not disclose the monoclonality of the gamma T cell recepter gene. We consider that it is very important to recognize this pseudolymphoma syndrome due to carbamazepine to avoid possibly subjecting the patient to unnecessary chemotherapy.
Saeki
H
H
Division of Dermatology, Tokyo Teishin Hospital, Japan.
Etoh
T
T
Toda
K
K
Mihm
M C
MC
D000328:Adult; D018692:Antimanic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D015139:Blotting, Southern; D002220:Carbamazepine / Q000009:adverse effects* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006801:Humans; D019310:Pseudolymphoma / Q000139:chemically induced* / Q000473:pathology; D012559:Schizophrenia / Q000188:drug therapy*; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology; D013577:Syndrome
D018692:Antimanic Agents; D002220:Carbamazepine