Malignant trophoblastic disease following a twin pregnancy consisting of a complete hydatiform mole and a normal fetus and placenta. A case report.
We report an unusual pregnancy with a complete hydatiform mole coexisting with a normal fetus and placenta. This report stresses the importance of a correct diagnosis and the dilemmas the clinician is faced with when managing such a case. Malignant trophoblastic disease occurs in 55% of complete hydatiform mole and fetus. Two-thirds require combination chemotherapy.
Vandeginste
S
S
Department of Obstetrics and Gynaecology, University Hospitals Leuven, Belgium.
Vergote
I B
IB
Hanssens
M
M
Moerman
P
P
Page
G
G
Van Den Berghe
K
K
Van Assche
A
A
D000020:Abortifacient Agents, Nonsteroidal / Q000627:therapeutic use; D000028:Abortion, Induced / Q000379:methods; D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D002820:Hydatidiform Mole, Invasive / Q000175:diagnosis* / Q000188:drug therapy; D008727:Methotrexate / Q000627:therapeutic use; D016595:Misoprostol / Q000627:therapeutic use; D011247:Pregnancy; D011272:Pregnancy, Multiple; D014328:Trophoblastic Neoplasms / Q000175:diagnosis; D014427:Twins; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000188:drug therapy
D000020:Abortifacient Agents, Nonsteroidal; D000964:Antimetabolites, Antineoplastic; D016595:Misoprostol; D008727:Methotrexate