title: Combined posterior chamber phakic intraocular lens and laser in situ keratomileusis: bioptics for extreme myopia.
abstract: OBJECTIVE
  To examine the efficacy, predictability, stability, and safety of combined posterior chamber phakic intraocular lens (IOL) implantation and laser in situ keratomileusis (LASIK) in eyes with extreme myopia.
  
  
  METHODS
  We analyzed the results of 67 eyes that received a posterior chamber hydrogel-collagen plate phakic IOL (STAAR Collamer Implantable Contact Lens) and also underwent secondary LASIK for the correction of extreme myopia. Mean follow-up was 3 months after the LASIK portion of the procedure (range, 1 day to 6 mo after LASIK).
  
  
  RESULTS
  Mean preoperative spherical equivalent refraction was -23.00 +/- 3.60 D (range, -18.75 to -35.00 D), and mean refractive cylinder was 1.50 +/- 1.20 D (range, 0 to 5.00 D). Mean spherical equivalent refraction after IOL implantation and before LASIK was -6.00 +/- 2.80 D (range, -2.00 to -14.38 D) and mean refractive cylinder 1.50 +/- 1.10 D (range, 0 to 5.00 D). Mean postoperative spherical equivalent refraction at last examination after the LASIK portion of the two-part phakic IOL-LASIK procedure was -0.20 +/- 0.90 D (range, +1.75 to -5.13 D), and mean refractive cylinder was 0.50 +/- 0.50 (range, 0 to 2.25 D). Eighty-five percent (57 eyes) were within +/- 1.00 D and 67% (45 eyes) were within +/- 0.50 D of emmetropia at last examination. The refractions remained stable with a statistically insignificant change (P > .05 at each interval) during follow-up. Postoperative uncorrected visual acuity at last examination was 20/20 or better in 3% (2 eyes) and 20/40 or better in 69% (46 eyes). A gain of 2 or more lines of spectacle-corrected visual acuity was seen in 51 eyes (76%) and no eyes lost 2 or more lines of spectacle-corrected visual acuity at last examination.
  
  
  CONCLUSIONS
  Combined posterior chamber phakic IOL implantation with the STAAR Collamer plate lens and LASIK (bioptics) is an effective and reasonably predictable method for correcting myopia from -18 to -35 D. Gains in spectacle-corrected visual acuity were common, and results demonstrated good short-term safety and refractive stability.
authors.affiliation: Instituto Zaldivar, Mendoza, Argentina.
authors.forename: R
authors.initials: R
authors.lastname: Zaldivar
authors.forename: J M
authors.initials: JM
authors.lastname: Davidorf
authors.forename: S
authors.initials: S
authors.lastname: Oscherow
authors.forename: G
authors.initials: G
authors.lastname: Ricur
authors.forename: V
authors.initials: V
authors.lastname: Piezzi
mesh_terms: D000328:Adult; D003315:Cornea / Q000601:surgery*; D016039:Corneal Transplantation / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D012029:Refraction, Ocular; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014792:Visual Acuity