title: Courageous science: structural studies of bluetongue virus core.
abstract: The structure of the bluetongue virus core was recently reported and represents the largest structure determined to atomic resolution. As a biological machine capable of RNA transcription, the structure has immense biological significance.
authors.affiliation: Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907-1392, USA. mgr@indiana.bio.purdue.edu
authors.forename: M G
authors.initials: MG
authors.lastname: Rossmann
authors.forename: Y
authors.initials: Y
authors.lastname: Tao
mesh_terms: D001820:Bluetongue virus / Q000502:physiology / Q000648:ultrastructure*; D002213:Capsid / Q000648:ultrastructure; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D011487:Protein Conformation; D012367:RNA, Viral / Q000096:biosynthesis; D013329:Structure-Activity Relationship; D014158:Transcription, Genetic; D014758:Viral Core Proteins / Q000737:chemistry* / Q000502:physiology; D014779:Virus Replication
chemical_list: D012367:RNA, Viral; C074954:VP3 protein, Bluetongue virus; D014758:Viral Core Proteins; C066862:VP7 protein, orbivirus