title: Seroprevalence of Helicobacter pylori infection in Malaysian children: evidence for ethnic differences in childhood.
abstract: OBJECTIVE
  To determine the prevalence of Helicobacter pylori (H. pylori) in healthy Malaysian children and to discover whether differences exist among children of different races.
  
  
  METHODS
  Serum samples from asymptomatic children tested for H. pylori seropositivity using an ELISA test.
  
  
  RESULTS
  Five hundred and fourteen healthy urban Malaysian children aged 0.5 to 17 (mean 5.9) years from three different racial groups had their blood tested for H. pylori antibodies. The overall prevalence was 10.3%. There was no significant difference in the prevalence of infection between boys and girls, but a significant rise was noted with increasing age (P = 0.009). Seropositivity was most common in the Indians and lowest in the Malays (P = 0.001). Father's level of education did not affect the child's rate of H. pylori seropositivity.
  
  
  CONCLUSIONS
  The prevalence of H. pylori seropositivity among asymptomatic urban Malaysian children is lowest in Malays. Intermediate in Chinese and highest in Indians. The racial differences found in children are consistent with those found in Malaysian adults.
authors.affiliation: Department of Paediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.
authors.forename: C C
authors.initials: CC
authors.lastname: Boey
authors.forename: K L
authors.initials: KL
authors.lastname: Goh
authors.forename: W S
authors.initials: WS
authors.lastname: Lee
authors.forename: N
authors.initials: N
authors.lastname: Parasakthi
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D044466:Asian People; D002648:Child; D002675:Child, Preschool; D002681:China / Q000208:ethnology; D003906:Developing Countries; D005260:Female; D006306:Health Surveys; D016481:Helicobacter Infections / Q000208:ethnology* / Q000382:microbiology*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D015994:Incidence; D007194:India / Q000208:ethnology; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D012016:Reference Values; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D017678:Sex Distribution