3-Hydroxyglutaric and glutaric acids are neurotoxic through NMDA receptors in vitro.
Kölker
S
S
Department of Neuropediatrics and Metabolic Diseases, Philipps University of Marburg, Germany.
Ahlemeyer
B
B
Krieglstein
J
J
Hoffmann
G F
GF
D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D002642:Chick Embryo; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology; D005977:Glutarates / Q000378:metabolism* / Q000494:pharmacology / Q000633:toxicity; D009474:Neurons / Q000187:drug effects* / Q000378:metabolism; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism*
C108959:3-hydroxyglutaric acid; D018691:Excitatory Amino Acid Antagonists; D005977:Glutarates; D016194:Receptors, N-Methyl-D-Aspartate; C035736:glutaric acid