title: Acute eosinophilic interstitial nephritis and uveitis (TINU syndrome) associated with granulomatous hepatitis.
abstract: A 23-year-old male presented with renal failure, cholestatic liver enzyme elevation and uveitis. Percutaneous renal biopsy revealed marked eosinophilic infiltration of the renal interstitium, which made the diagnosis of TINU syndrome (Tubulo-Interstitial Nephritis and Uveitis). Percutaneous liver biopsy showed granulomatous hepatitis, which was not described as a part of TINU syndrome. The diagnostic dilemma and the literature are discussed.
authors.affiliation: Department of Internal Medicine, Meir General Hospital, Kfar-Sava, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Segev
authors.forename: S
authors.initials: S
authors.lastname: Ben-Chitrit
authors.forename: Y
authors.initials: Y
authors.lastname: Orion
authors.forename: F
authors.initials: F
authors.lastname: Segev
authors.forename: J
authors.initials: J
authors.lastname: Bernheim
authors.forename: J
authors.initials: J
authors.lastname: Bernheim
authors.forename: Y A
authors.initials: YA
authors.lastname: Mekori
mesh_terms: D000208:Acute Disease; D000328:Adult; D004802:Eosinophilia / Q000150:complications*; D006099:Granuloma / Q000150:complications; D006505:Hepatitis / Q000150:complications*; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000150:complications*; D013577:Syndrome; D014605:Uveitis / Q000150:complications*