title: Suicidal ideation and attempts: a longitudinal investigation of children of depressed and well mothers.
abstract: OBJECTIVE
  This study uses a prospective longitudinal design to examine suicidality (ideation, plans, attempts, and completions) in children and adolescents, to compare suicidality in the offspring of depressed and well mothers, and to identify correlates and predictors of suicidality.
  
  
  METHODS
  Two children (n = 192) from each of the families in an ongoing longitudinal study of the offspring of mothers with major depressive disorder (n = 42), with bipolar disorder (n = 26), or without past or current psychiatric diagnosis (n = 30) were studied. Assessment of suicidality, based on diagnostic interviews, was made when the younger of the sibling pairs were approximately 6, 9, and 14 years of age and older siblings were approximately 6, 9, 13, and 18 years of age.
  
  
  RESULTS
  Children of depressed mothers were more likely to report suicidal thoughts or behaviors than were children of well mothers (particularly the older sibling cohort). Developmental trajectories of suicidality differed for offspring of mothers with major depressive disorder and bipolar disorder. Links were found between lifetime reports of suicidality and the adolescent's mood problems (e.g., hypomanic behavior), coping strategies, and parental rejection. Also, child's and mother's suicidality were related.
  
  
  CONCLUSIONS
  These findings have implications for planning interventions targeted at preventing suicide in youth.
authors.affiliation: Section on Developmental Psychopathology, NIMH, Bethesda, MD 20892, USA.
authors.forename: B
authors.initials: B
authors.lastname: Klimes-Dougan
authors.forename: K
authors.initials: K
authors.lastname: Free
authors.forename: D
authors.initials: D
authors.lastname: Ronsaville
authors.forename: J
authors.initials: J
authors.lastname: Stilwell
authors.forename: C J
authors.initials: CJ
authors.lastname: Welsh
authors.forename: M
authors.initials: M
authors.lastname: Radke-Yarrow
mesh_terms: D000293:Adolescent; D001714:Bipolar Disorder / Q000523:psychology*; D002648:Child; D002657:Child Development; D016241:Child of Impaired Parents / Q000523:psychology*; D003866:Depressive Disorder / Q000523:psychology*; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D009035:Mothers / Q000523:psychology*; D011446:Prospective Studies; D013223:Statistics as Topic; D013405:Suicide / Q000523:psychology*