title: Statistical textural features for detection of microcalcifications in digitized mammograms.
abstract: Clustered microcalcifications on X-ray mammograms are an important sign for early detection of breast cancer. Texture-analysis methods can be applied to detect clustered microcalcifications in digitized mammograms. In this paper, a comparative study of texture-analysis methods is performed for the surrounding region-dependence method, which has been proposed by the authors, and conventional texture-analysis methods, such as the spatial gray-level dependence method, the gray-level run-length method, and the gray-level difference method. Textural features extracted by these methods are exploited to classify regions of interest (ROI's) into positive ROI's containing clustered microcalcifications and negative ROI's containing normal tissues. A three-layer backpropagation neural network is used as a classifier. The results of the neural network for the texture-analysis methods are evaluated by using a receiver operating-characteristics (ROC) analysis. The surrounding region-dependence method is shown to be superior to the conventional texture-analysis methods with respect to classification accuracy and computational complexity.
authors.affiliation: Software Center, Corporate Technical Operations, Samsung Electronics Co., Ltd., Seoul, Korea.
authors.forename: J K
authors.initials: JK
authors.lastname: Kim
authors.forename: H W
authors.initials: HW
authors.lastname: Park
mesh_terms: D001941:Breast Diseases / Q000000981:diagnostic imaging*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging; D002114:Calcinosis / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008327:Mammography; D016571:Neural Networks, Computer; D012372:ROC Curve; D011856:Radiographic Image Enhancement / Q000379:methods*; D015203:Reproducibility of Results