Cytomegalovirus-associated transverse myelitis in a non-immunocompromised patient.
Cytomegalovirus (CMV)-associated transverse myelitis is rare in immunocompetent patients. The case of a 54-year-old man is reported here who developed acute transverse myelitis with cerebrospinal fluid (CSF) alterations, suggesting a central nervous system infection. CMV-IgM positivity in serum and CMV isolated from blood, positive CMV PCR and positivity for pp65 antigen in blood, without viral antigens in the CSF and a positive response to therapy with ganciclovir (followed by progressive improvement) supported the diagnosis.
Giobbia
M
M
Infectious Disease Dept., General Hospital Ca Foncello, Treviso, Italy.
Carniato
A
A
Scotton
P G
PG
Marchiori
G C
GC
Vaglia
A
A
D000914:Antibodies, Viral / Q000097:blood / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000097:blood / Q000188:drug therapy / Q000276:immunology / Q000821:virology*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D009188:Myelitis, Transverse / Q000097:blood / Q000188:drug therapy / Q000276:immunology / Q000821:virology*; D010750:Phosphoproteins / Q000276:immunology; D014763:Viral Matrix Proteins / Q000276:immunology
D000914:Antibodies, Viral; D000956:Antigens, Viral; D010750:Phosphoproteins; D014763:Viral Matrix Proteins; C065418:cytomegalovirus matrix protein 65kDa