title: Primary Sjögren's syndrome and its lymphoid malignancy: a report of four cases.
abstract: OBJECTIVE
  To evaluate the incidence and spectrum of malignancy of primary Sjögren's syndrome (pSS).
  
  
  METHODS
  250 pSS who were followed-up in Peking Union Medical College (PUMC) Hospital were analyzed.
  
  
  RESULTS
  Four of them were diagnosed with histopathological findings of 2 non-Hodgkin Lymphoma, 1 AILD, 1 multiple myeloma. Two died of secondary infection while receiving chemotherapy for lymphoma, 2 remained remitted.
  
  
  CONCLUSIONS
  The risk factors were persistent enlargement of major salivary glands, appearance of monoclonal serum lg, and disappearance of auto antibodies.
authors.affiliation: Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Dong
authors.forename: Y
authors.initials: Y
authors.lastname: Zhao
authors.forename: X
authors.initials: X
authors.lastname: Zeng
authors.forename: D
authors.initials: D
authors.lastname: Sun
mesh_terms: D000328:Adult; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D005260:Female; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000473:pathology; D012307:Risk Factors; D012859:Sjogren's Syndrome / Q000473:pathology*