title: Assessment of left ventricular systolic function and diastolic time intervals by the bioimpedance polyrheocardiographic system.
abstract: In order to detect left ventricular systolic function and diastolic time intervals using a new improved bioimpedance polyrheocardiographic system (BPCS), 110 healthy subjects and 128 patients with myocardial infarction were examined. Twenty-four simultaneous measurements of cardiac output by thermodilution and BPCS were performed in 11 patients with complicated acute left ventricular failure. Studies demonstrated a high degree of correlation (r = 0.91, p < 0.001). The correlation between the methods of using signals of the second derivative and the subtracted first derivative waveform of BPCS and continuous-wave Doppler echocardiography of systolic and diastolic time intervals was studies in 51 patients. The methods were closely correlated, especially with respect to left ventricular ejection time (r = 0.95), isovolumic relaxation time (r = 0.85), time to peak filling (r = 0.90), and deceleration of rapid filling time (r = 0.91). New bioimpedance hemodynamic parameters such as peak volume acceleration of ejection (PVAE) and peak power ejection (PPE) in patients with heart failure (NYHA Class I-III) were studied. Significant reductions of PVAE and PPE in groups of patients with marked progression of heart failure were noted. These results have demonstrated that BPCS is a noninvasive, simple accurate method of assessment of left ventricular systolic function and diastolic time intervals.
authors.affiliation: Department of Introduction into Internal Diseases, Perm Medical Academy, City Clinical Hospital, Russia.
authors.forename: M
authors.initials: M
authors.lastname: Zubarev
authors.forename: A
authors.initials: A
authors.lastname: Dumler
authors.forename: V
authors.initials: V
authors.lastname: Shutov
authors.forename: N
authors.initials: N
authors.lastname: Popov
mesh_terms: D000328:Adult; D002302:Cardiac Output; D002307:Cardiography, Impedance / Q000379:methods*; D003971:Diastole; D004395:Dye Dilution Technique; D006334:Heart Function Tests; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology*; D013318:Stroke Volume / Q000502:physiology; D013599:Systole; D016277:Ventricular Function, Left / Q000502:physiology*