[Thrombospondins, tumor angiogenesis and breast cancer].
Thrombospondin-1 and -2 are extracellular matrix proteins that are overexpressed in breast cancer tissue. Their role in breast cancer remains unknown. This article reviews the potential effects of thrombospondin-1 and -2 in breast cancer tumori genesis and metastatic dissemination.
Clézardin
P
P
INSERM Unité 403, Faculté de Médecine Laënnec, Lyon, France.
Bruno-Bossio
G
G
Fontana
A
A
Serre
C M
CM
Magnetto
S
S
Frappart
L
L
D001943:Breast Neoplasms / Q000098:blood supply* / Q000473:pathology; D015815:Cell Adhesion Molecules / Q000502:physiology*; D005260:Female; D006801:Humans; D009389:Neovascularization, Pathologic; D019700:Thrombospondin 1 / Q000502:physiology*; D019699:Thrombospondins / Q000502:physiology*; D000099262:Thrombospondin 2
D015815:Cell Adhesion Molecules; D019700:Thrombospondin 1; D019699:Thrombospondins; D000099262:Thrombospondin 2
Thrombospondines, angiogenèse tumorale et cancer du sein.