title: [Significance of esophagocardiac reflexes for inducing thoracic pain].
abstract: In the clinical setting the cardiologists' interest is focussed on the esophagus as a potential source of thoracic pain as a differential diagnosis of angina pectoris. However, visceral afferences originating in the mucosal wall of the esophagus activated by acid exposure may also influence cardiac function. The available data convincingly demonstrate a reduction of the exertional angina threshold and changes of the ECG (ST segment depression and arrhythmia). These effects are most likely due to a reduced coronary blood flow.
authors.affiliation: Abteilung für Gastroenterologie und Hepatologie, Universitätsklinikum Essen. g.holtmann@uni-essen.de
authors.forename: G
authors.initials: G
authors.lastname: Holtmann
authors.forename: P
authors.initials: P
authors.lastname: Schlömer
authors.forename: G
authors.initials: G
authors.lastname: Gerken
mesh_terms: D000344:Afferent Pathways / Q000502:physiology; D000787:Angina Pectoris / Q000209:etiology / Q000503:physiopathology*; D001341:Autonomic Nervous System / Q000503:physiopathology; D002637:Chest Pain / Q000209:etiology / Q000503:physiopathology*; D003327:Coronary Disease / Q000175:diagnosis / Q000503:physiopathology; D004947:Esophagus / Q000294:innervation*; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000503:physiopathology; D006321:Heart / Q000294:innervation*; D006801:Humans; D012018:Reflex / Q000502:physiology*
vernacular_title: Bedeutung ösophagokardialer Reflexe für die Auslösung von Brustschmerzen.