[Castleman's disease in the retroperitoneal region].
OBJECTIVE
To describe a case of Castleman's disease presenting as a retroperitoneal mass, with special reference to the differential diagnosis from other retroperitoneal lesions. The histological features, variants, clinical manifestations, etiopathogenesis and treatment of Castleman's disease are reviewed.


METHODS
A 64-year-old male presented with voiding symptoms and hypogastric pain. An ultrasound scan showed a 5 x 6 cm mass located behind the bladder and above the prostate, which was confirmed by an abdomino-pelvic CT scan.


RESULTS
Retroperitoneal sarcoma was suspected and the mass was resected. The histopathological analysis showed giant lymphoid hyperplasia (vascular hyaline variant of Castleman's disease).


CONCLUSIONS
Retroperitoneal Castleman's disease is a lymphoproliferative disorder with two well-defined histological types and a mixed variant. Although this lesion is frequently localized to the mediastinum (71%), extrathoracic lesions have been described. Definitive diagnosis is based on the postoperative pathological findings.
Pérez García
F J
FJ
Servicio de Urología, Hospital Central de Asturias, Oviedo, España.
Martínez Gómez
F J
FJ
Fernández Gómez
J M
JM
Regadera Sejas
F J
FJ
Rodríguez Martínez
J J
JJ
Sanchez Trilla
A
A
San Martín Blanco
A
A
Seco Navedo
M A
MA
D005871:Castleman Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D012509:Sarcoma / Q000175:diagnosis / Q000000981:diagnostic imaging; D014463:Ultrasonography
Enfermedad de Castleman de localización retroperitoneal.