title: Childhood Churg-Strauss syndrome.
abstract: Churg-Strauss syndrome or allergic granulomatosis and angiitis is a vasculitis that is found in adults, but is extremely rare in children. We describe a 14-year-old boy who presented with prolonged fever, weight loss, sinusitis, myalgia and arthralgia, testicular pain, pulmonary infiltrations, pericardial effusion, peripheral neuropathy, and eosinophilia. Muscle biopsy showed necrotizing arteritis with eosinophil infiltration. His clinical course was complicated by several seizures secondary to cerebral vasculitis and severe asthma, resulting in death. The clinical features and outcomes of childhood Churg-Strauss syndrome are reviewed.
authors.affiliation: Department of Medicine, Faculty of Medicine, Chiang Mai University, Thailand.
authors.forename: W
authors.initials: W
authors.lastname: Louthrenoo
authors.forename: A
authors.initials: A
authors.lastname: Norasetthada
authors.forename: S
authors.initials: S
authors.lastname: Khunamornpong
authors.forename: A
authors.initials: A
authors.lastname: Sreshthaputra
authors.forename: W
authors.initials: W
authors.lastname: Sukitawut
mesh_terms: D000293:Adolescent; D001706:Biopsy; D001921:Brain / Q000000981:diagnostic imaging; D015267:Churg-Strauss Syndrome / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology; D014057:Tomography, X-Ray Computed