Chlamydial colonization of multiple mucosae following infection by any mucosal route.
Chlamydia trachomatis inoculated by any mucosal route colonized multiple murine mucosae and, in most cases, the spleen, liver, and kidneys. Cell-to-cell transmission, systemic dissemination, and autoinoculation of infectious fluids may have contributed to chlamydial spread. Intermucosal trafficking of protective T cells cannot be accurately evaluated by using live chlamydial challenges.
Perry
L L
LL
Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA.
Hughes
S
S
D000818:Animals; D002690:Chlamydia Infections / Q000276:immunology / Q000382:microbiology* / Q000473:pathology / Q000503:physiopathology; D002692:Chlamydia trachomatis / Q000502:physiology*; D005260:Female; D018928:Immunity, Mucosal; D051379:Mice; D008810:Mice, Inbred C57BL; D009092:Mucous Membrane / Q000276:immunology / Q000382:microbiology