title: Innovative technology for tissue disruption by explosive-induced shock waves.
abstract: We have developed a novel, less invasive, shock wave source that can be introduced into an arbitrary position in a human body percutaneously. Using this technique we can disrupt cells locally. The shock wave source consists of an explosive, an optical fiber, a balloon catheter, and a Nd:YAG laser, which generates a spherical explosive shock wave. The destructive potential of the present source for injuring tissue was confirmed and the subsequent cell elongation and split in the direction of the shock wave has been observed.
authors.affiliation: Shock Wave Research Center, Tohoku University, Japan. kodama@helix.mgh.harvard.edu
authors.forename: T
authors.initials: T
authors.lastname: Kodama
authors.forename: H
authors.initials: H
authors.lastname: Uenohara
authors.forename: K
authors.initials: K
authors.lastname: Takayama
mesh_terms: D000818:Animals; D001386:Azides; D002404:Catheterization; D005336:Fiber Optic Technology; D006801:Humans; D007834:Lasers; D008099:Liver / Q000293:injuries; D055100:Optical Fibers; D011817:Rabbits; D018030:Silver Compounds; D014465:Ultrasonics
chemical_list: D001386:Azides; D018030:Silver Compounds; C041170:silver azide