title: Functional and structural analysis of the subunits of human transcription factor TFIID.
abstract: The past few years have brought many new insights concerning the structure and function of TAFII proteins. In the future, further biochemical and structural studies will no doubt lead to a greater understanding of the molecular organization of TFIID complexes. A better understanding of the function of metazoan, in particular, mammalian, TAFIIs in cell cycle progression and gene activation will, however, require the use of novel genetic techniques in addition to the biochemical analyses.
authors.affiliation: Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, Illkirch, C.U. de Strasbourg, France.
authors.forename: I
authors.initials: I
authors.lastname: Davidson
authors.forename: C
authors.initials: C
authors.lastname: Romier
authors.forename: A C
authors.initials: AC
authors.lastname: Lavigne
authors.forename: C
authors.initials: C
authors.lastname: Birck
authors.forename: G
authors.initials: G
authors.lastname: Mengus
authors.forename: O
authors.initials: O
authors.lastname: Poch
authors.forename: D
authors.initials: D
authors.lastname: Moras
mesh_terms: D000818:Animals; D002460:Cell Line; D019281:Dimerization; D006801:Humans; D046911:Macromolecular Substances; D008322:Mammals; D008958:Models, Molecular; D017433:Protein Structure, Secondary; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics; D035362:Transcription Factor TFIID; D019473:Transcription Factors, TFII / Q000737:chemistry* / Q000378:metabolism*; D014158:Transcription, Genetic; D014162:Transfection
chemical_list: D046911:Macromolecular Substances; D011994:Recombinant Proteins; D035362:Transcription Factor TFIID; D019473:Transcription Factors, TFII