Isolation and structural determination of a novel bicyclic taxane diterpene from needles of the Chinese yew, Taxus mairei.
A novel bicyclic taxane diterpene with a rare 12-membered ring was isolated from needles of the Chinese yew, Taxus mairei, and its structure was established as (3E, 8E)-2 alpha, 7 beta, 9, 10 beta, 13 alpha, 20-hexaacetoxy-5(2'-acetoxy-cinnamoyloxy)-3,8-secotaxa -3,8,11-triene (1) with the help of 1D and 2D NMR data. The relative stereochemistry was deduced from a NOESY experiment.
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Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Oritani
T
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Sugiyama
T
T
Yamada
T
T
D001643:Bridged Bicyclo Compounds / Q000737:chemistry* / Q000302:isolation & purification; D002681:China; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010946:Plants, Medicinal / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
C120174:2,7,9,10,13,20-hexaacetoxy-5-(2'-acetoxycinnamoyloxy)-3,8-secotaxa-3,8,11-triene; D001643:Bridged Bicyclo Compounds