title: Multifocal peripheral bronchial carcinoid tumour.
abstract: Peripheral bronchial carcinoids sometimes arise as single solid or nodular lesions in the periphery of the lung. We encountered a 74-year-old Japanese male with bronchial carcinoids that were widely disseminated throughout the lung parenchyma. Pulmonary function tests revealed mild airflow obstruction. A metastatic process was ruled out from primary malignancy and a histological examination revealed findings consistent with a peripheral bronchial carcinoid. Based on these findings, we concluded that this patient had a primary multifocal peripheral bronchial carcinoid. An immunohistochemical examination revealed immunoreactivity for chromogranin A and bombesin. The present case appears to be an unusual case of diffuse multifocal peripheral bronchial carcinoid, confirmed by immunohistochemistry.
authors.affiliation: First Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Akashiba
authors.forename: K
authors.initials: K
authors.lastname: Matsumoto
authors.forename: N
authors.initials: N
authors.lastname: Kosaka
authors.forename: O
authors.initials: O
authors.lastname: Saito
authors.forename: T
authors.initials: T
authors.lastname: Horie
authors.forename: N
authors.initials: N
authors.lastname: Nemoto
mesh_terms: D000368:Aged; D000402:Airway Obstruction / Q000175:diagnosis / Q000209:etiology; D001706:Biopsy; D001839:Bombesin; D001984:Bronchial Neoplasms / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D002276:Carcinoid Tumor / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D053379:Chromogranin A; D002864:Chromogranins; D017809:Fatal Outcome; D006728:Hormones / Q000097:blood; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed
chemical_list: D053379:Chromogranin A; D002864:Chromogranins; D006728:Hormones; D001839:Bombesin