[Kidney].
Kidney is one of the major target organ for angiotensin II (AT-II). The presence of three types of AT-II receptors, AT-II type 1, type 2, type 4 receptor (AT1, AT2, and AT4 receptor, respectively) were reported in kidney. AT1 receptor is the main type of receptor in kidney and mediates most of physiological effects of AT-II in kidney. The population of AT2 receptor is small in kidney. However, AT2 receptor also seems to play an important role for development and apoptosis in kidney. AT4 receptor is the receptor for angiotensin IV, but the physiological function is still unknown.
Imanishi
K
K
Third Department of Internal Medicine, Kumamoto University School of Medicine.
Nonoguchi
H
H
Tomita
K
K
D006801:Humans; D007668:Kidney / Q000737:chemistry*; D007684:Kidney Tubules / Q000737:chemistry; D011945:Receptors, Angiotensin / Q000032:analysis* / Q000502:physiology
D011945:Receptors, Angiotensin