title: Chlamydial colonization of multiple mucosae following infection by any mucosal route.
abstract: Chlamydia trachomatis inoculated by any mucosal route colonized multiple murine mucosae and, in most cases, the spleen, liver, and kidneys. Cell-to-cell transmission, systemic dissemination, and autoinoculation of infectious fluids may have contributed to chlamydial spread. Intermucosal trafficking of protective T cells cannot be accurately evaluated by using live chlamydial challenges.
authors.affiliation: Laboratory of Intracellular Parasites, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana 59840, USA.
authors.forename: L L
authors.initials: LL
authors.lastname: Perry
authors.forename: S
authors.initials: S
authors.lastname: Hughes
mesh_terms: D000818:Animals; D002690:Chlamydia Infections / Q000276:immunology / Q000382:microbiology* / Q000473:pathology / Q000503:physiopathology; D002692:Chlamydia trachomatis / Q000502:physiology*; D005260:Female; D018928:Immunity, Mucosal; D051379:Mice; D008810:Mice, Inbred C57BL; D009092:Mucous Membrane / Q000276:immunology / Q000382:microbiology