title: Apoptosis induced by propolis in human hepatocellular carcinoma cell line.
abstract: Propolis has been reported to exhibit a wide spectrum of activities including antibiotic, antiviral, anti-inflammatory, immunostimulatory and tumor carcinostatic properties. We showed propolis induced apoptosis in a human hepatoma cell line (SNU449) by FITC-Annexin V/PI staining. We also compared the apoptosis inducing effect between Korean and Commercial (Sigma # p-1010) propolis. There was no difference on apoptosis between them.
authors.affiliation: Department of Pathology, Chun-Chon Sacred Heart Hospital, Hallym University, Chun-Chon city, Kang Won-Do 200-060, Korea.
authors.forename: Y H
authors.initials: YH
authors.lastname: Choi
authors.forename: W Y
authors.initials: WY
authors.lastname: Lee
authors.forename: S Y
authors.initials: SY
authors.lastname: Nam
authors.forename: K C
authors.initials: KC
authors.lastname: Choi
authors.forename: Y E
authors.initials: YE
authors.lastname: Park
mesh_terms: D017304:Annexin A5 / Q000378:metabolism; D017209:Apoptosis / Q000187:drug effects*; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D053938:DNA Fragmentation / Q000187:drug effects; D016650:Fluorescein-5-isothiocyanate; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D011419:Propidium; D011429:Propolis / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
chemical_list: D017304:Annexin A5; D011419:Propidium; D011429:Propolis; D016650:Fluorescein-5-isothiocyanate