title: Prevalence of prostatic intraepithelial (PIN) in surgical resections.
abstract: OBJECTIVE
  To determine the prevalence of prostatic intraepithelial neoplasia (PIN) in surgical specimens and assess its relationship to adenocarcinoma.
  
  
  METHODS
  205 surgical specimens (191) transurethral resections, 6 open prostatectomies, 8 needle biopsies) reported at the University Department of Pathology, Colombo over 64 months were reviewed.
  
  
  RESULTS
  There were 170 benign hyperplasias and 35 adenocarcinomas. PIN I was present in 22.92% PIN II in 5.36% and PIN III in 7.32% of the specimens. 8.51%, 27.27% and 93.3% PIN I, PIN II and III were associated with invasive adenocarcinoma. Nine cases (4.39%) had high grade PIN (PIN II & III) in the absence of adenocarcinoma.
  
  
  CONCLUSIONS
  PIN II & III were strongly associated with coexistent carcinoma but PIN I was not. The finding of high grade PIN in surgical biopsies with no obvious adenocarcinoma warrants examination of all available tissue and deep sections.
authors.affiliation: Dept. of Pathology, Faculty of Medicine, University of Colombo, Sri Lanka.
authors.forename: M V
authors.initials: MV
authors.lastname: de Silva
authors.forename: M S
authors.initials: MS
authors.lastname: Fernando
authors.forename: A M
authors.initials: AM
authors.lastname: Abeygunasekera
authors.forename: S A
authors.initials: SA
authors.lastname: Serozsha Goonewardene
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology / Q000601:surgery; D006801:Humans; D008297:Male; D015995:Prevalence; D019048:Prostatic Intraepithelial Neoplasia / Q000453:epidemiology* / Q000601:surgery; D011471:Prostatic Neoplasms / Q000453:epidemiology* / Q000601:surgery