title: Benign epileptic discharges in patients with lesional partial epilepsies.
abstract: Case reports of four patients with therapy-resistant lesional partial epilepsies and additional foci of benign epileptic discharges of childhood, in addition to the usual electroencephalogram (EEG) changes, are presented. A family history of epileptic or febrile seizures in childhood was reported in all four patients. A distant relative of one patient, not manifesting seizures, demonstrated rolandic spikes on EEG. An abnormal pregnancy (polyhydramnion, premature pains, induced labor because of an abnormal CTG , placenta insufficiency) was reported in one patient, risk factors during birth (birth 14 days after term, placenta insufficiency) were reported in one, and bacterial meningitis at 4 weeks of age was reported in one. All patients manifested a retarded, partly severe, unfavorable infantile psychomotor development. An early seizure onset was observed in all patients (in three patients during the first year of life and in one patient during the second year). A hemifacial seizure symptomatology was seen, in addition to other symptoms, in two patients, possibly indicating the seizure pattern indicative of benign partial seizures; seizures occurred exclusively in sleep in one patient. The benign focus was never located in the lesional area. It was recorded over the same hemisphere in two patients and over the other hemisphere in the other two.
authors.affiliation: Epilepsy Centre Bethel, Bielefeld, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Degen
authors.forename: H
authors.initials: H
authors.lastname: Holthausen
authors.forename: T
authors.initials: T
authors.lastname: Pieper
authors.forename: I
authors.initials: I
authors.lastname: Tuxhorn
authors.forename: P
authors.initials: P
authors.lastname: Wolf
mesh_terms: D002540:Cerebral Cortex / Q000503:physiopathology*; D002658:Developmental Disabilities / Q000209:etiology / Q000503:physiopathology; D004569:Electroencephalography; D017029:Epilepsy, Complex Partial / Q000150:complications / Q000235:genetics / Q000503:physiopathology* / Q000601:surgery; D005192:Family Health; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male