title: Malignant otitis externa.
abstract: BACKGROUND
  Malignant otitis externa is an infrequent but severe infection of the external auditory canal, most often affecting elderly diabetic patients. Early diagnosis is necessary due to its high morbidity and mortality.
  
  
  METHODS
  From 1990 to 1997, all patients with malignant otitis externa at the Veterans General Hospital-Taipei were reviewed retrospectively. The clinical features and the strategy of diagnosis and treatment are discussed.
  
  
  RESULTS
  Twelve patients with an average age of 65.3 years were included. Eleven of these patients were diabetic. All had the presenting symptoms of otalgia and otorrhea at diagnosis. Bacterial cultures grew Pseudomonas aeruginosa in eight patients and methicillin-resistant Staphylococcus aureus in four patients. The mean duration of admission was 82 days. Appropriate antibiotics were given according to the results of bacterial culture and sensitivity test. 99Technetium scans and 67gallium scans were performed to evaluate the extent of involvement and monitor the effects of treatment. Eventually, four patients died due to renal failure, meningitis, pneumonia and upper gastrointestinal bleeding, respectively.
  
  
  CONCLUSIONS
  Malignant otitis externa is a life-threatening infection arising from the external auditory canal. A high degree of suspicion for malignant otitis externa is mandatory. Vigorous local and systemic antimicrobial treatment should be initiated early in the course of the disease to achieve a satisfactory outcome. 99Technetium and 67gallium scans are important for the diagnosis and evaluation of the treatment results.
authors.affiliation: Department of Otolaryngology, Veterans General Hospital-Taipei, Taiwan, ROC.
authors.forename: L H
authors.initials: LH
authors.lastname: Yu
authors.forename: C H
authors.initials: CH
authors.lastname: Shu
authors.forename: T Y
authors.initials: TY
authors.lastname: Tu
authors.forename: A S
authors.initials: AS
authors.lastname: Shiao
authors.forename: C F
authors.initials: CF
authors.lastname: Lien
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010032:Otitis Externa / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D011379:Prognosis