title: Drug interactions in the intensive care unit.
abstract: Adverse drug reactions are a major source of complications in the intensive care unit. Drug interactions contribute significantly to the incidence of adverse drug reactions. The intensive care unit clinician must remain aware of the major mechanisms for drug interactions, which are reviewed in this article.
authors.affiliation: School of Pharmacy, University of California San Francisco, USA.
authors.forename: D R
authors.initials: DR
authors.lastname: Romac
authors.forename: T E
authors.initials: TE
authors.lastname: Albertson
mesh_terms: D017677:Age Distribution; D000368:Aged; D016638:Critical Illness / Q000628:therapy*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D010599:Pharmacokinetics; D018570:Risk Assessment
chemical_list: D003577:Cytochrome P-450 Enzyme System