Rational use of chemotherapy. It is not just rat poison.
The role of chemotherapy in the management of advanced prostate cancer is expanding. Multiple regimens that use a variety of drugs have been developed. A chemotherapy regimen may appear to be a collection of randomly chosen agents. This article presents the theoretic foundation for the development of combination chemotherapy.
Kamradt
J M
JM
Department of Internal Medicine, University of Michigan Cancer Center, Ann Arbor, USA.
Klein
E A
EA
Pienta
K J
KJ
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002470:Cell Survival / Q000187:drug effects; D019008:Drug Resistance, Neoplasm; D006801:Humans; D007939:Leukemia L1210 / Q000188:drug therapy / Q000473:pathology; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology; D051381:Rats
D000970:Antineoplastic Agents