Multilocus sequence typing: molecular typing of bacterial pathogens in an era of rapid DNA sequencing and the internet.
Multilocus sequence typing is a development of multilocus enzyme electrophoresis in which the alleles at multiple house-keeping loci are assigned directly by nucleotide sequencing, rather than indirectly from the electrophoretic mobilities of their gene products. A major advantage of this approach is that sequence data are unambiguous and electronically portable, allowing molecular typing of bacterial pathogens (or other infectious agents) via the Internet.
Spratt
B G
BG
Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, South Parks Road, Oxford, OX1 3PS, UK. brian.spratt@zoo.ox.ac.uk
D001419:Bacteria / Q000145:classification / Q000235:genetics; D015373:Bacterial Typing Techniques; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D005798:Genes, Bacterial / Q000235:genetics*; D006801:Humans; D020407:Internet; D017422:Sequence Analysis, DNA
D004269:DNA, Bacterial