title: Practical pointers for grappling with GERD. Heartburn gnaws at quality of life for many patients.
abstract: GERD is a common condition, generally caused by transient LES relaxations. The spectrum of disease due to GERD is wide, ranging from symptoms alone to esophagitis, Barrett's esophagus, and respiratory tract complications. Excellent diagnostic test are available to confirm the diagnosis and stage the disease, and medications can predictably relieve symptoms and heal even the most severe forms of esophagitis. Finally, surgical therapy is an effective option for patients with truly refractory disease or for those patients with significant disease who prefer not to use drug treatment.
authors.affiliation: Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Szarka
authors.forename: G R
authors.initials: GR
authors.lastname: Locke
mesh_terms: D001471:Barrett Esophagus / Q000209:etiology; D005764:Gastroesophageal Reflux / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D006356:Heartburn / Q000209:etiology; D006801:Humans
chemical_list: D005765:Gastrointestinal Agents