title: A new scoring system for the clinical diagnosis of catheter-related infections.
abstract: It is difficult to make the clinical diagnosis of catheter-related infections using the available and established definitions of the HICPAC (Hospital Infection Control Practices Advisory Committee) of the CDC (Centers for Disease Control, definitions of nosocomial infections). The scoring system shown here is a modification of these definitions and has enabled the causal relationship between the catheter and clinical episodes of systemic infections to be quantitatively graded. The scoring system included the following criteria: height and rate of rise of body temperature, attendant shivering, identification of pathogens in blood and/or catheter tip cultures, improvement in the clinical course after catheter removal, signs of catheter exit site inflammation and results of diagnostic tests for other possible sources of infection. These criteria were graded using points and weighted according to their specificity. The comparative evaluation of 65 episodes of systemic infections using the scoring system and the diagnostic criteria of HICPAC showed agreement in 85%. No case was graded "false-negative." In nine of ten false-positive cases additional findings supported the presence of a catheter-associated infection. This scoring system appears, therefore, to be more sensitive than existing diagnostic criteria, without loss of specificity.
authors.affiliation: Klinik mit Poliklinik für Kinder und Jugendliche, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Lugauer
authors.forename: A
authors.initials: A
authors.lastname: Regenfus
authors.forename: M
authors.initials: M
authors.lastname: Böswald
authors.forename: P
authors.initials: P
authors.lastname: Martus
authors.forename: C
authors.initials: C
authors.lastname: Geis
authors.forename: T
authors.initials: T
authors.lastname: Bechert
authors.forename: J
authors.initials: J
authors.lastname: Greil
authors.forename: J P
authors.initials: JP
authors.lastname: Guggenbichler
mesh_terms: D002405:Catheterization, Central Venous / Q000009:adverse effects*; D006801:Humans; D007239:Infections / Q000175:diagnosis* / Q000503:physiopathology; D018805:Sepsis / Q000175:diagnosis / Q000276:immunology / Q000503:physiopathology