title: Biochemistry and haematology values for the baboon (Papio hamadryas): the effects of sex, growth, development and age.
abstract: A retrospective study evaluated the influence of sex and age on plasma biochemistry and haematology parameters in a captive-bred colony of baboons. Over 1,140 ETDA and heparin blood samples were obtained from 160 clinically normal baboons between the ages of 11 months and 11 years. Data for these blood tests were analysed for the effects of sex, age and sex age interactions. Sex, age and sex age interactions were detected for many plasma biochemistry and haematological parameters. The reference range values for platelets, white-blood cells and mean corpuscular volume and plasma chloride, glucose, total protein and iron were higher (P < 0.01) and red blood cell, plasma sodium, potassium, total CO2, creatinine, urea, total bilirubin, albumin, alkaline phosphate, gamma glutamyl transpeptidase and phosphate were lower (P < 0.01) in the female compared to the male population. Sex age interactions (P < 0.05) were seen with haemoglobin, white blood cells, haematocrit, mean corpuscular volume, sodium, creatinine, urea, calcium, phosphate, total bilirubin, total protein alkaline phosphatase, the liver enzymes and triglycerides. Plasma alkaline phosphatase was highest ( > 800 micro/l) in young juveniles of both sexes; creatinine was higher in older ( > 4 years) compared to younger baboons of the same sex (P < 0.05). Plasma cholesterol and triglycerides were greater (P < 0.01) in young baboons compared to older animals.
authors.affiliation: Department of Renal Medicine, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
authors.forename: W J
authors.initials: WJ
authors.lastname: Harewood
authors.forename: A
authors.initials: A
authors.lastname: Gillin
authors.forename: A
authors.initials: A
authors.lastname: Hennessy
authors.forename: J
authors.initials: J
authors.lastname: Armistead
authors.forename: J S
authors.initials: JS
authors.lastname: Horvath
authors.forename: D J
authors.initials: DJ
authors.lastname: Tiller
mesh_terms: D000367:Age Factors; D000818:Animals; D001774:Blood Chemical Analysis; D005260:Female; D006405:Hematology; D008297:Male; D010215:Papio / Q000097:blood* / Q000254:growth & development*; D012016:Reference Values; D012189:Retrospective Studies; D012727:Sex Characteristics