[Investigation and identification of the antimicrobial component of the drug "Tomatol"].
Antimicrobial activity of Tomatol against laboratory strains of Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 6538-P and Candida albicans ATCC 885-653 as well as against clinical isolates of Enterobacter spp., Streptococcus spp., Staphylococcus spp., Klebsiella spp. and Escherichia spp. was tested. Tomatol was shown to have a broad antimicrobial spectrum including gram-positive and gram-negative organisms and Candida. The TLC investigation demonstrated that the Tomatol antimicrobial component was that of a complex of organic acids such as succinic, citric, tartaric and others.
Vorob'ev
A A
AA
I.M. Sechenov Moscow Medical Academy.
Seleznev
A S
AS
Pavlova
L A
LA
Iang
A
A
Ershova
N N
NN
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D018551:Solanum lycopersicum / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents
Izuchenie i identifikatsiia antimikrobnogo komponenta preparata "Tomatol".