Aging and Muscle Loss.
Aging is associated with a decrease in fat-free mass, an increase in fat mass, and progressive impairment of muscle function and performance. Diminishing anabolic hormone levels and progressive declines in muscle protein turnover contribute to the multifactorial pathophysiology of age-associated sarcopenia. The potential effects of anabolic hormone replacement on body composition and functional capacity are only beginning to be studied.
Bross
R
Charles R. Drew University of Medicine and Science, Los Angeles, CA 90049, USA.
Storer
T
Bhasin
S