title: [Place of chemotherapy in the treatment of invasive bladder tumors].
abstract: Urothelial bladder tumours are chemosensitive. Chemotherapy is indicated in the case of metastatic bladder cancer. The M-VAC protocol remains the reference treatment. The efficacy of this protocol is estimated to be about 18% in terms of complete responses and 20% of these responding patients achieve long-term survival. New combinations, comprising drugs such as ifosfamide, gallium nitrate, paclitaxel or gemcitabine, appear to be promising. Neoadjuvant and adjuvant chemotherapy cannot be considered to be standard treatment at the present time.
authors.affiliation: Service d'Urologie, Groupe Hospitalier Pellegrin, Bordeaux, France.
authors.forename: J L
authors.initials: JL
authors.lastname: Pariente
authors.forename: C
authors.initials: C
authors.lastname: Theodore
authors.forename: J L
authors.initials: JL
authors.lastname: Davin
authors.forename: P
authors.initials: P
authors.lastname: Rischmann
authors.forename: D
authors.initials: D
authors.lastname: Chopin
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage; D009361:Neoplasm Invasiveness; D015996:Survival Rate; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy* / Q000473:pathology; D014747:Vinblastine / Q000008:administration & dosage
chemical_list: D014747:Vinblastine; D004317:Doxorubicin; D002945:Cisplatin; D008727:Methotrexate
vernacular_title: Place de la chimiothérapie dans le traitement des tumeurs infiltrantes de la vessie.