11-Deoxycorticosterone-producing adrenocortical carcinoma.
A woman presented with a history of weight loss and muscle weakness. A laboratory test revealed hypokalemia and elevation of plasma 11-deoxycorticosterone (DOC). CT showed a left adrenal mass. A left adrenalectomy was performed. The histological and immunohistochemical diagnosis showed a DOC-producing adrenocortical carcinoma. This cancer is very rare; only 10 cases including the present case have appeared in the literature.
Egoshi
K
K
Department of Urology and Pathology, Teikyo University Ichihara Hospital, Ichihara, Japan.
Masai
M
M
Nagao
K
K
Ito
H
H
D000306:Adrenal Cortex Neoplasms / Q000378:metabolism* / Q000601:surgery; D000315:Adrenalectomy; D018268:Adrenocortical Carcinoma / Q000378:metabolism* / Q000601:surgery; D003900:Desoxycorticosterone / Q000096:biosynthesis* / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D016896:Treatment Outcome
D003900:Desoxycorticosterone