Apoptosis induced by propolis in human hepatocellular carcinoma cell line.
Propolis has been reported to exhibit a wide spectrum of activities including antibiotic, antiviral, anti-inflammatory, immunostimulatory and tumor carcinostatic properties. We showed propolis induced apoptosis in a human hepatoma cell line (SNU449) by FITC-Annexin V/PI staining. We also compared the apoptosis inducing effect between Korean and Commercial (Sigma # p-1010) propolis. There was no difference on apoptosis between them.
Choi
Y H
YH
Department of Pathology, Chun-Chon Sacred Heart Hospital, Hallym University, Chun-Chon city, Kang Won-Do 200-060, Korea.
Lee
W Y
WY
Nam
S Y
SY
Choi
K C
KC
Park
Y E
YE
D017304:Annexin A5 / Q000378:metabolism; D017209:Apoptosis / Q000187:drug effects*; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D053938:DNA Fragmentation / Q000187:drug effects; D016650:Fluorescein-5-isothiocyanate; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D011419:Propidium; D011429:Propolis / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D017304:Annexin A5; D011419:Propidium; D011429:Propolis; D016650:Fluorescein-5-isothiocyanate