title: Novel approaches for discovering industrial enzymes.
abstract: New technologies for enzyme discovery are changing the rules of the game for industrial biocatalysis. More kinds of enzymes are available, their hardiness is increasing, and their costs are coming down. These changes are the key drivers for a rebirth of interest in industrial applications of enzymes. The major enabling discovery approaches include screening of biodiversity, genomic sequencing, directed evolution and phage display.
authors.affiliation: Hercules Incorporated, Hercules Research Center, 500 Hercules Road, Wilmington, DE 19808, USA.
authors.forename: B
authors.initials: B
authors.lastname: Marrs
authors.forename: S
authors.initials: S
authors.lastname: Delagrave
authors.forename: D
authors.initials: D
authors.lastname: Murphy
mesh_terms: D019020:Directed Molecular Evolution; D004798:Enzymes / Q000235:genetics / Q000302:isolation & purification*; D007218:Industrial Microbiology; D016296:Mutagenesis; D017422:Sequence Analysis, DNA
chemical_list: D004798:Enzymes