Hepatitis D infectivity profile among hepatitis B infected hospitalised patients in Calcutta.
450 hospitalised cases of hepatic and non hepatic disorders and 100 normal individuals were examined for serum Hepatitis B Surface antigen and Delta Virus antigen by ELISA to find out its association with different clinical disorders. 105 patients (23.3%) and 2 control (2%) were positive for HBsAG. 60 cases with jaundice (26%) were HBsAg positive. 65% of HBsAg positive jaundiced patients had serum bilirubin level more than 2 mg per dl with a mean SGPT level of 488 iu/L. Only two cases were positive for HDV antigen among 60 HBsAg positive jaundice patients indicating a lower rate of prevalence of infection (3.3%). 62 (59%) out of 105 HBsAg positive cases did not show any history of blood transfusion or surgical interference indicating a positive HBV transmission through needle prick during investigative procedures.
Bhattacharyya
S
S
Department of Microbiology, N.R.S. Medical College, Calcutta.
Dalal
B S
BS
Lahiri
A
A
D000410:Alanine Transaminase / Q000097:blood; D000956:Antigens, Viral / Q000097:blood; D001803:Blood Transfusion; D004797:Enzyme-Linked Immunosorbent Assay; D006509:Hepatitis B / Q000150:complications* / Q000635:transmission; D006514:Hepatitis B Surface Antigens / Q000097:blood*; D003699:Hepatitis D / Q000150:complications / Q000453:epidemiology*; D003698:Hepatitis Delta Virus / Q000276:immunology; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007565:Jaundice / Q000097:blood / Q000453:epidemiology* / Q000821:virology; D014504:Urban Health
D000956:Antigens, Viral; D006514:Hepatitis B Surface Antigens; D000410:Alanine Transaminase