title: [Distinct genotypes of TTV infection in non A-non C hepatitis].
abstract: TTV DNA was tested by polymerase chain reaction with two set primers(NG061/NG063, T801/T935) in patients with nonA-nonC acute and chronic hepatitis. TTV DNA was detected in 75.9-100% by T801/T935, 47.1-48.3% by NG061/NG063 of 46 patients. The nucleotide sequences including 185 bp in the N22 region of 22 TTV DNA isolates from patients with acute and chronic nonA-nonC hepatitis, were classified into various TTV genotypes such as 1a, 1b and non-1. Our results demonstrate that genotype 1b may induce hepatic injury.
authors.forename: H
authors.initials: H
authors.lastname: Hoshino
authors.forename: K
authors.initials: K
authors.lastname: Hino
authors.forename: Y
authors.initials: Y
authors.lastname: Iwasa
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Sandai
authors.forename: K
authors.initials: K
authors.lastname: Yoshisawa
authors.forename: S
authors.initials: S
authors.lastname: Iino
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D015415:Biomarkers / Q000032:analysis; D004266:DNA Virus Infections / Q000453:epidemiology / Q000821:virology*; D004267:DNA Viruses / Q000235:genetics*; D004279:DNA, Viral / Q000032:analysis*; D005838:Genotype; D006525:Hepatitis, Viral, Human / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction
chemical_list: D015415:Biomarkers; D004279:DNA, Viral