title: The relative accuracy of the clinical estimation of the duration of life for patients with end of life cancer.
abstract: BACKGROUND
  Although the prediction of the duration of life of patients with end of life cancer most often relies on the clinical estimation of survival (CES) made by the treating physician, the accuracy and practical value of CES remains controversial.
  
  
  METHODS
  The authors prospectively evaluated the accuracy of CES in an inception and population-based cohort of 233 cancer patients who were seen at the onset of their terminal phase. They also systematically reviewed the literature on CES in advanced or end-stage cancer patients in MEDLINE, CANCERLIT, and EMBASE data bases, using two search strategies developed by a research librarian.
  
  
  RESULTS
  CES had low sensitivity in detecting patients who died within shorter time frames (< or =2 months), and a tendency to overestimate survival was noted. A moderate correlation was observed between actual survival (AS) and CES (Pearson correlation coefficient = 0.47, intraclass correlation coefficient = 0.46, weighted kappa coefficient = 0.42).
  
  
  CONCLUSIONS
  Treating physicians appear to overestimate the duration of life of end of life ill cancer patients, particularly those patients who die early in the terminal phase and who may potentially benefit from earlier participation in palliative care programs. CES should be considered one of many criteria, rather than a unique criterion, by which to choose therapeutic intervention or health care programs for patients in the end of life cancer phase.
authors.affiliation: Division of Palliative Care Medicine, Grey Nuns Hospital, Edmonton, Alberta, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Viganò
authors.forename: M
authors.initials: M
authors.lastname: Dorgan
authors.forename: E
authors.initials: E
authors.lastname: Bruera
authors.forename: M E
authors.initials: ME
authors.lastname: Suarez-Almazor
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008017:Life Expectancy; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000401:mortality*; D011237:Predictive Value of Tests; D011379:Prognosis; D012680:Sensitivity and Specificity; D013727:Terminal Care