The role of Chlamydia trachomatis infection in cervical cancer development.
Previous Chlamydia trachomatis infection elevates expression of: 1. TGFalpha in CIN I, CIN II, CIN III; 2. HPV 16 in CIN I, CIN II, CIN III and invasive carcinoma; 3. Ki 67 in CIN III and invasive carcinoma. Chronic Chlamydial infection is very often associated with cervical hypertrophy.
Markowska
J
J
Oncology K. Marcinkowski University of Medicine Sciences, Poznań, Poland.
Fischer
N
N
Filas
V
V
Fischer
Z
Z
Breborowicz
J
J
Markowski
M
M
D016022:Case-Control Studies; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D066246:ErbB Receptors / Q000378:metabolism; D005260:Female; D006801:Humans; D019394:Ki-67 Antigen / Q000378:metabolism; D027383:Papillomaviridae / Q000302:isolation & purification; D016211:Transforming Growth Factor alpha / Q000378:metabolism; D002583:Uterine Cervical Neoplasms / Q000209:etiology* / Q000382:microbiology* / Q000473:pathology
D019394:Ki-67 Antigen; D016211:Transforming Growth Factor alpha; D066246:ErbB Receptors