title: Anthelmintic resistance in sheep and goat farms on Peninsular Malaysia.
abstract: The faecal egg count reduction test (FECRT) was conducted on 39 sheep farms and 9 goat farms located in Peninsular Malaysia. The anthelmintic groups used in these tests were the benzimidazoles, levamisole, the benzimidazole/levamisole combination, macrocyclic lactones and closantel. Results indicated that the prevalence of resistance to the benzimidazole group was high, with approximately 50% of the sheep farms and 75% of the goat farms having resistant nematode parasite populations present. Resistance to levamisole, closantel and ivermectin was also detected. Differentiation of the infective larvae derived from faecal cultures indicated that by far the most predominant parasite species was Haemonchus contortus.
authors.affiliation: Veterinary Research Institute, Ipoh Perak, Malaysia. chandra@jphvri.po.my
authors.forename: P
authors.initials: P
authors.lastname: Chandrawathani
authors.forename: M
authors.initials: M
authors.lastname: Adnan
authors.forename: P J
authors.initials: PJ
authors.lastname: Waller
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology* / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D001562:Benzimidazoles / Q000494:pharmacology / Q000627:therapeutic use; D004351:Drug Resistance; D005243:Feces / Q000469:parasitology; D015511:Goat Diseases / Q000188:drug therapy* / Q000469:parasitology; D006041:Goats; D006188:Haemonchiasis / Q000188:drug therapy*; D006189:Haemonchus / Q000187:drug effects*; D007559:Ivermectin / Q000494:pharmacology / Q000627:therapeutic use; D007978:Levamisole / Q000494:pharmacology / Q000627:therapeutic use; D018942:Macrolides; D008296:Malaysia; D010270:Parasite Egg Count / Q000662:veterinary; D015995:Prevalence; D012458:Salicylanilides / Q000494:pharmacology / Q000627:therapeutic use; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000469:parasitology
chemical_list: D000871:Anthelmintics; D000900:Anti-Bacterial Agents; D001562:Benzimidazoles; D018942:Macrolides; D012458:Salicylanilides; D007978:Levamisole; D007559:Ivermectin; C031000:benzimidazole; C023342:closantel; C027837:moxidectin