title: Longitudinal changes in optic disc topography of adult patients after trabeculectomy.
abstract: OBJECTIVE
  To study longitudinal changes in optic disc topography after trabeculectomy in adult patients.
  
  
  METHODS
  Prospective case series.
  
  
  METHODS
  Twenty-five eyes of 25 patients undergoing trabeculectomy were enrolled.
  
  
  METHODS
  Images of the optic disc were obtained preoperatively and approximately 2 weeks, 4 months, and 8 months after surgery by use of a confocal scanning laser ophthalmoscope (Heidelberg Retina Tomograph).
  
  
  METHODS
  The topographic optic disc parameters (cup volume, cup area, rim volume, rim area, cup-disc area ratio, mean cup depth, maximum depth, cup shape, and height variation contour) were measured automatically for each image with the Heidelberg Retina Tomograph Software (version 1.11).
  
  
  RESULTS
  Approximately 2 weeks after surgery, the mean preoperative intraocular pressure (IOP) of 19.3 mmHg (SD, 6.4 mmHg) decreased to 6.0 mmHg (SD, 3.6 mmHg), cup volume and mean cup depth decreased, height variation contour increased, and the cup shape parameter became more negative. Approximately 4 months after surgery, mean IOP was 9.7 mmHg (SD, 4.2 mmHg), and the only statistically significant change from preoperative values of optic disc parameters was in the cup shape measure. Approximately 8 months after surgery, there was no statistically significant change in any of the optic disc parameters compared with preoperative values, although IOP was 10.4 mmHg (SD, 5.9 mmHg).
  
  
  CONCLUSIONS
  Changes in the optic disc that may be present 2 weeks after a trabeculectomy do not appear to persist 4 and 8 months later in eyes with advanced glaucomatous optic nerve damage, except for cup shape, which was different from preoperative values at 4 months but not at 8 months.
authors.affiliation: Jules Stein Eye Institute and Department of Ophthalmology, University of California Los Angeles, School of Medicine 90095-7004, USA.
authors.forename: F
authors.initials: F
authors.lastname: Topouzis
authors.forename: F
authors.initials: F
authors.lastname: Peng
authors.forename: R
authors.initials: R
authors.lastname: Kotas-Neumann
authors.forename: R
authors.initials: R
authors.lastname: Garcia
authors.forename: J
authors.initials: J
authors.lastname: Sanguinet
authors.forename: F
authors.initials: F
authors.lastname: Yu
authors.forename: A L
authors.initials: AL
authors.lastname: Coleman
mesh_terms: D000368:Aged; D005260:Female; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D007834:Lasers; D008137:Longitudinal Studies; D008297:Male; D019721:Ophthalmoscopes; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D011446:Prospective Studies; D014054:Tomography; D014130:Trabeculectomy