title: Low-frequency damped electroretinographic wavelets in young asymptomatic patients with dominant retinitis pigmentosa: a new electroretinographic finding.
abstract: OBJECTIVE
  To describe a previously unreported electroretinographic (ERG) pattern in early retinitis pigmentosa (RP).
  
  
  METHODS
  Two case reports.
  
  
  METHODS
  Two unrelated young asymptomatic patients with autosomal-dominant retinitis pigmentosa were studied.
  
  
  METHODS
  Clinical findings and ERG responses were assessed.
  
  
  RESULTS
  No ERG responses were detected scotopically with low-luminance stimuli. With increasingly brighter stimuli, a series of three to five low-frequency damped wavelets developed under both scotopic and photopic conditions. The period of the wavelets was 25 to 37 msec.
  
  
  CONCLUSIONS
  Low-frequency damped ERG wavelets occur in some young asymptomatic patients with autosomal-dominant RP. The ERG pattern suggests that these wavelets are predominantly cone-generated.
authors.affiliation: Bascom Palmer Eye Institute, University of Miami School of Medicine, Florida, USA.
authors.forename: B L
authors.initials: BL
authors.lastname: Lam
authors.forename: M
authors.initials: M
authors.lastname: Liu
authors.forename: D I
authors.initials: DI
authors.lastname: Hamasaki
mesh_terms: D000328:Adult; D002648:Child; D003623:Dark Adaptation; D004596:Electroretinography; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D010375:Pedigree; D010775:Photic Stimulation; D020419:Photoreceptor Cells, Vertebrate / Q000502:physiology*; D012174:Retinitis Pigmentosa / Q000235:genetics / Q000503:physiopathology*; D014792:Visual Acuity; D014794:Visual Fields