title: Synthesis and evaluation of 4-(3-methyl-2-butenoxy) isonitrosoacetophenone, a radiation-induced stress metabolite in Citrus.
abstract: The time- and dose-dependent occurrence of 4-(3-methyl-2-butenoxy)isonitrosoacetophenone, a gamma-irradiation-induced stress metabolite was investigated. The chemical synthesis of the compound is reported. The compound exhibits antifungal activity, as well as antioxidant activity, as indicated by its ability to scavenge reactive oxygen radicals in a chemiluminescence assay.
authors.affiliation: Department of Chemistry and Biochemistry, Rand Afrikaans University, Auckland Park, South Africa.
authors.forename: I A
authors.initials: IA
authors.lastname: Dubery
authors.forename: A E
authors.initials: AE
authors.lastname: Louw
authors.forename: F R
authors.initials: FR
authors.lastname: van Heerden
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000975:Antioxidants / Q000138:chemical synthesis / Q000494:pharmacology; D002957:Citrus / Q000378:metabolism* / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D008163:Luminescent Measurements; D010658:Phenylglyoxal / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
chemical_list: C120121:4-(3-methyl-2-butenoxy)isonitrosoacetophenone; D000935:Antifungal Agents; D000975:Antioxidants; C057115:isonitrosoacetophenone; D010658:Phenylglyoxal