Iridoid and seco-iridoid glucosides from Chioccoca alba (Rubiaceae).
Phytochemical investigation of Chioccoca alba afforded three new iridoids, alboside I, alboside II and alboside III, and a new seco-iridoid alboside V. Alboside IV showed moderate activity towards the DNA repair-deficient mutant RS321 of Saccharomyces cerevisiae. The structural elucidation of the new compounds was performed by ES-MS and by 1D and 2D NMR spectroscopic methods.
Carbonezi
C A
CA
Instituto de Química, Universidade Estadual Paulista, Araraquara, SP, Brazil.
Martins
D
D
Young
M C
MC
Lopes
M N
MN
Furlan
M
M
Rodriguez Filho
E
E
Bolzani
V da S
Vda S
D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D039823:Iridoids; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D011714:Pyrans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019666:Rubiaceae / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D013057:Spectrum Analysis
D005960:Glucosides; D039823:Iridoids; D011714:Pyrans