[The use of nontraditional approaches to the analysis of the effects of radiation on the system of protein phosphorylation in spleen lymphocytes].
Postradiation disturbances in functioning of Ca(2+)- and cyclic nucleotide-dependent protein kinase systems are established. Kinetic index of different protein kinases of spleen lymphocytes under irradiation with doses of 0.5 and 1 Gy are analysed using return-cards-construction and Lyapunov's-coefficient-determination methods. It is shown that determined disturbances can be considered as a part of general unspecific adaptational reaction of lymphocytes to irradiation.
Ostapchenko
L I
LI
Taras Shevchenko Kiev National University, Ukraine. ostaps@molphys.ups.kiev.ua
Nalevina
O E
OE
Kucherenko
N E
NE
D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism; D006152:Cyclic GMP / Q000378:metabolism; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D007700:Kinetics; D008214:Lymphocytes / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D008954:Models, Biological; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism*; D051381:Rats; D013154:Spleen / Q000378:metabolism / Q000528:radiation effects*
D000242:Cyclic AMP; D011494:Protein Kinases; D006152:Cyclic GMP
Ispol'zovanie netraditsionnykh podkhodov dlia analiza vliianiia oblucheniia na osobennosti funktsionirovaniia sistem fosforilirovaniia belkov v limfotsitakh selezenki]