title: Limits of clinical signs and non-invasive techniques in detecting severe acute rejection.
abstract: We describe a cadaveric renal transplant patient with an early post-transplant period characterized by normal urine output, normal clinical and biological signs, and a slow decrease of serum creatinine; repeated ultrasonography, color doppler ultrasonography and renal angioscintigraphy were normal or consistent with a clinical diagnosis of mild acute tubular necrosis. Nevertheless a core renal biopsy revealed severe steroid-resistant acute rejection with diffuse infiltrates of lymphocytes and initial transmural arteritis.
authors.affiliation: Renal Unit, Ospedale di Careggi, Firenze, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Bertoni
authors.forename: L
authors.initials: L
authors.lastname: Di Maria
authors.forename: R
authors.initials: R
authors.lastname: Piperno
authors.forename: M
authors.initials: M
authors.lastname: Zanazzi
authors.forename: A
authors.initials: A
authors.lastname: Rosati
authors.forename: L
authors.initials: L
authors.lastname: Moscarelli
authors.forename: M
authors.initials: M
authors.lastname: Salvadori
mesh_terms: D000208:Acute Disease; D006084:Graft Rejection / Q000175:diagnosis*; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity