title: Synthesis of some new biologically active thiadiazolotriazinones--Part II.
abstract: 4-Amino-6-phenyl/methyl-3-mercapto-1,2,4-triazin-5(4H)-ones (1) are condensed with an aromatic carboxylic acid, aryloxyacetic acid or anilinoacetic acid (2), to yield 7-substituted-3-phenyl/methyl-4H-1,3,4-thiadiazolo-[2,3-c]-1,2,4-+ ++triazin-4- ones (3). Phosphorus oxychloride is used as a cyclizing agent. All the synthesized compounds are screened for their antibacterial activities against S. aureus, E. coli, P. aeruginosa and G. bacillus.
authors.affiliation: Mangalore University, Department of Post Graduate Studies and Research in Chemistry, Mangalagangothri, India.
authors.forename: B S
authors.initials: BS
authors.lastname: Holla
authors.forename: B K
authors.initials: BK
authors.lastname: Sarojini
authors.forename: K
authors.initials: K
authors.lastname: Shridhara
authors.forename: G
authors.initials: G
authors.lastname: Antony
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D015394:Molecular Structure; D014227:Triazines / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D014227:Triazines