title: [Spinal tumors in infancy. A report of 48 cases].
abstract: BACKGROUND
  Spinal tumours in infancy are an infrequent oncological disorder. The clinical features, usually of insidious onset, are alterations in gait and a painful spine.
  
  
  OBJECTIVE
  To analyze the different histological types of spinal tumours seen in infancy and their form of presentation in our series.
  
  
  METHODS
  We reviewed the clinical histories of 48 patients with intraspinal tumours, aged under 15 years, whose reports of histological diagnosis had been sent to our centre.
  
  
  RESULTS
  Of the patients studied, 17 were girls (35.4%) and 31 boys (64.6%) with an average age of 7.7 years. The histological diagnoses made most frequently were astrocytomas (22.9%) and lipomas (18.8%) followed by metastases (12.5%), ependymomas (8.3%) and Edwing's sarcoma (8.3%). The clinical features were present prior to diagnosis for between 1 and 6 months in 13 patients, and for less than one month in 9 patients. The presenting symptoms were alterations in gait and back pain in most patients. Exploratory tests were related to the involvement of long vias and second motor-neurone lesions. The main topographical findings were: in the axial plane the lesions were extradural (23 patients) and in the sagittal plane there was dorsal involvement (34 patients).
  
  
  CONCLUSIONS
  Insidious, progressive alterations in gait together with continuous, nocturnal back pain are valuable data when a serious spinal disorder is to be suspected. Early diagnosis should be based on neuroimaging tests, essentially MR, in the patients in whom spinal cord involvement is considered.
authors.affiliation: Sección de Neurología Infantil, Hospital Universitario 12 de Octubre, Madrid, España. daperezm@yahoo.com
authors.forename: D A
authors.initials: DA
authors.lastname: Pérez-Martínez
authors.forename: H J
authors.initials: HJ
authors.lastname: Bueno
authors.forename: F
authors.initials: F
authors.lastname: Gutiérrez
authors.forename: E
authors.initials: E
authors.lastname: López-Laso
authors.forename: A I
authors.initials: AI
authors.lastname: Puente-Muñoz
authors.forename: J
authors.initials: J
authors.lastname: Esparza
authors.forename: R
authors.initials: R
authors.lastname: Simón
authors.forename: F
authors.initials: F
authors.lastname: Mateos
mesh_terms: D000293:Adolescent; D001254:Astrocytoma / Q000150:complications / Q000473:pathology*; D001416:Back Pain / Q000175:diagnosis / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004806:Ependymoma / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008067:Lipoma / Q000150:complications / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009069:Movement Disorders / Q000175:diagnosis / Q000209:etiology; D012189:Retrospective Studies; D012509:Sarcoma / Q000150:complications / Q000473:pathology*; D013125:Spinal Neoplasms / Q000150:complications / Q000473:pathology*
vernacular_title: Tumores espinales en la infancia. Presentación de 48 casos.