title: Severe apnoeas following immunisation in premature infants.
abstract: Four premature infants developed apnoeas severe enough to warrant resuscitation after immunisation with diphtheria, pertussis, and tetanus (DPT), and Haemophilus influenzae B (Hib). One required re-intubation and ventilation. Although apnoeas after immunisation are recognised, they are not well documented. It is time for further research to elucidate the best time to immunise such infants.
authors.affiliation: Department of Paediatrics Royal Hampshire County Hospital Winchester Hampshire, UK.
authors.forename: M H
authors.initials: MH
authors.lastname: Slack
authors.forename: D
authors.initials: D
authors.lastname: Schapira
mesh_terms: D001049:Apnea / Q000209:etiology*; D016667:Bacterial Capsules; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000009:adverse effects*; D005260:Female; D005865:Gestational Age; D018073:Haemophilus Vaccines / Q000009:adverse effects*; D006801:Humans; D007114:Immunization / Q000009:adverse effects*; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D011135:Polysaccharides, Bacterial / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D015721:Diphtheria-Tetanus-Pertussis Vaccine; D018073:Haemophilus Vaccines; C044237:Haemophilus influenzae type b polysaccharide vaccine; D011135:Polysaccharides, Bacterial