title: Simple tandem repeat polymorphisms in the neuronal nitric oxide synthase gene in different ethnic populations.
abstract: Allelic frequencies of a CA dinucleotide repeat in exon 29 and an intronic AAT trinucleotide repeat in the neuronal nitric oxide synthase (NOS1) gene were determined by simple sequence length polymorphism (SSLP) in 305 American-Caucasian and 105 African-American healthy subjects. There were highly significant differences in allele frequencies between the two ethnically diverse study populations.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass. 02115, USA.
authors.forename: H
authors.initials: H
authors.lastname: Grasemann
authors.forename: J M
authors.initials: JM
authors.lastname: Drazen
authors.forename: A
authors.initials: A
authors.lastname: Deykin
authors.forename: E
authors.initials: E
authors.lastname: Israel
authors.forename: G T
authors.initials: GT
authors.lastname: De Sanctis
authors.forename: A
authors.initials: A
authors.lastname: Pillari
authors.forename: C H
authors.initials: CH
authors.lastname: Yandava
mesh_terms: D000483:Alleles; D044383:Black People / Q000235:genetics*; D016009:Chi-Square Distribution; D004247:DNA / Q000737:chemistry / Q000235:genetics; D005787:Gene Frequency; D006801:Humans; D008969:Molecular Sequence Data; D019001:Nitric Oxide Synthase / Q000235:genetics*; D052248:Nitric Oxide Synthase Type I; D011110:Polymorphism, Genetic; D017422:Sequence Analysis, DNA; D020080:Tandem Repeat Sequences / Q000235:genetics*; D014481:United States; D044465:White People / Q000235:genetics*; D001741:Black or African American
chemical_list: D004247:DNA; C496320:NOS1 protein, human; D019001:Nitric Oxide Synthase; D052248:Nitric Oxide Synthase Type I