Uveitis associated with varicella virus vaccine.
OBJECTIVE
To report a case of uveitis associated with the live attenuated varicella virus vaccine (Varivax; Merck & Co, Inc, West Point, Pennsylvania) in a young, otherwise healthy girl.


METHODS
The time of onset of uveitis in relation to vaccination and the number and the pattern of distribution of vesicles were noted. The patient received oral acyclovir and topical steroids and cycloplegic drops.


RESULTS
The uveitis and vesicular rash improved significantly after 7 days of treatment. A literature review and communications with the drug's manufacturer disclosed no identifiable previous cases of uveitis associated with Varivax.


CONCLUSIONS
Uveitis should be recognized as a possible adverse side effect of the varicella vaccine.
Esmaeli-Gutstein
B
B
Ophthalmology Section, M.D. Anderson Cancer Center, Houston, Texas 77030-4095, USA. bgutstein@mdanderson.org
Winkelman
J Z
JZ
D000212:Acyclovir / Q000627:therapeutic use; D000293:Adolescent; D000869:Anterior Eye Segment / Q000473:pathology; D019433:Chickenpox Vaccine / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D014606:Uveitis, Anterior / Q000188:drug therapy / Q000209:etiology*; D014792:Visual Acuity
D019433:Chickenpox Vaccine; C009935:prednisolone acetate; D011239:Prednisolone; D000212:Acyclovir