title: [Castleman's disease in the retroperitoneal region].
abstract: OBJECTIVE
  To describe a case of Castleman's disease presenting as a retroperitoneal mass, with special reference to the differential diagnosis from other retroperitoneal lesions. The histological features, variants, clinical manifestations, etiopathogenesis and treatment of Castleman's disease are reviewed.
  
  
  METHODS
  A 64-year-old male presented with voiding symptoms and hypogastric pain. An ultrasound scan showed a 5 x 6 cm mass located behind the bladder and above the prostate, which was confirmed by an abdomino-pelvic CT scan.
  
  
  RESULTS
  Retroperitoneal sarcoma was suspected and the mass was resected. The histopathological analysis showed giant lymphoid hyperplasia (vascular hyaline variant of Castleman's disease).
  
  
  CONCLUSIONS
  Retroperitoneal Castleman's disease is a lymphoproliferative disorder with two well-defined histological types and a mixed variant. Although this lesion is frequently localized to the mediastinum (71%), extrathoracic lesions have been described. Definitive diagnosis is based on the postoperative pathological findings.
authors.affiliation: Servicio de Urología, Hospital Central de Asturias, Oviedo, España.
authors.forename: F J
authors.initials: FJ
authors.lastname: Pérez García
authors.forename: F J
authors.initials: FJ
authors.lastname: Martínez Gómez
authors.forename: J M
authors.initials: JM
authors.lastname: Fernández Gómez
authors.forename: F J
authors.initials: FJ
authors.lastname: Regadera Sejas
authors.forename: J J
authors.initials: JJ
authors.lastname: Rodríguez Martínez
authors.forename: A
authors.initials: A
authors.lastname: Sanchez Trilla
authors.forename: A
authors.initials: A
authors.lastname: San Martín Blanco
authors.forename: M A
authors.initials: MA
authors.lastname: Seco Navedo
mesh_terms: D005871:Castleman Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D012509:Sarcoma / Q000175:diagnosis / Q000000981:diagnostic imaging; D014463:Ultrasonography
vernacular_title: Enfermedad de Castleman de localización retroperitoneal.