[Value of free PSA/total PSA ratio in therapeutic decisions in the case of a single positive biopsy of the prostate].
OBJECTIVE
Study of the value of the free PSA/total PSA ratio in the therapeutic decision concerning prostatic adenocarcinoma, in the case of a single positive biopsy.


METHODS
The free PSA/total PAS ratio was calculated on serum samples derived from 37 patients with clinically localized prostatic carcinoma and only one positive biopsy, in whom radical prostatectomy was performed.


RESULTS
The free PSA/total PSA ratio appeared to be independent of pathological stage and histological prognostic criteria (grade and score, degree of capsular effraction).


CONCLUSIONS
In the case of a single positive biopsy, calculation of the free PSA/total PSA ratio does not appear to provide any decisional criteria in favour of radical prostatectomy.
Huyghe
E
E
Service de Chirurgie Urologique, CHU de Rangueil, Toulouse, France.
Soulie
M
M
Tollon
C
C
Escourrou
G
G
Pontonnier
F
F
Plante
P
P
D000230:Adenocarcinoma / Q000097:blood / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001706:Biopsy; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011467:Prostate / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000097:blood*; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies
D017430:Prostate-Specific Antigen
Intérêt dans la décision thérapeutique du rapport PSA libre/PSA total en cas de biopsie de prostate unipositive.