title: [Pilot study on early diagnosis of renal cell carcinoma by sonography].
abstract: The goal of this study was to investigate the practicability and effectiveness of a systematic screening for renal cell carcinoma by ultrasound in the course of the established German Health Ministry screening programs.
  
  
  METHODS
  In two centers (Mainz and Wuppertal) a screening program for renal cell carcinoma for all citizens (age > 40 years) was established. The screening was divided into two phases (time period 1 year): (1) All citizens over 40 years could attend voluntarily a cost-free ultrasound investigation. (2) A follow-up investigation for the entire screening population was provided.
  
  
  RESULTS
  Ten thousand volunteers attended the screening program. Mean age was 60 years. Thirteen renal cell carcinomas were detected. The incidence of other findings was 15%; none of those required further treatment.
  
  
  CONCLUSIONS
  Systematic screening for renal cell carcinoma by ultrasound is cost-effective and showed high acceptance and practicability in a German population. The rate of detection of renal cell carcinoma was higher than initially statistically calculated.
authors.affiliation: Urologische Klinik und Poliklinik der Johannes Gutenberg-Universität Mainz.
authors.forename: D
authors.initials: D
authors.lastname: Filipas
authors.forename: C
authors.initials: C
authors.lastname: Spix
authors.forename: D
authors.initials: D
authors.lastname: Schultz-Lampel
authors.forename: P
authors.initials: P
authors.lastname: Black
authors.forename: B
authors.initials: B
authors.lastname: Kater
authors.forename: S
authors.initials: S
authors.lastname: Roth
authors.forename: J
authors.initials: J
authors.lastname: Michaelis
authors.forename: J W
authors.initials: JW
authors.lastname: Thüroff
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000601:surgery; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000601:surgery; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D009392:Nephrectomy; D010865:Pilot Projects; D013997:Time Factors; D014463:Ultrasonography
vernacular_title: Pilotstudie zur sonographischen Früherkennung des Nierenzellkarzinoms.