title: [Strains of Shigella sonnei recently isolated in Tokyo].
abstract: A total of 341 Shigella sonnei strains consisting of 94 domestic strains and 247 imported strains isolated during 1990-1997 in Tokyo, were examined regarding their colicine-type, drug-resistance and ornithine-utilization. The colicine typing results showed that the domestic strains were classified into 7 types, and the imported strains were classified into 13 types. Among the colicine-types identified, 8-type, 0-type, 6-type and 12-type were predominant in the domestic strains, whereas 6-type, 0-type, 8-type, 9A-type and 12-type were predominant in the imported strains. The drug-resistance test using 9 drugs (CP, TC, SM, KM, ABPC, ST, NA, FOM and NFLX) showed that 89.4% of the domestic strains and 85.4% of the imported strains were resistant to some of the drugs except FOM and NFLX. Drugs with a high resistant rate were SM, TC and ST for both groups. Drug-resistance patterns of the resistant strains varied in 22 types. Among those, a triple drug-resistance type with TC.SM.ST was found in the most frequent pattern in both groups. The results of the ornithine-utilization test revealed that 28.7% of the domestic strains and 8.1% of the imported strains were negative. The ornithine-negative strains in the same source had a similar plasmid-profile, but generally there was no correlation between the different sources.
authors.affiliation: Department of Microbiology, Tokyo Metropolitan Research Laboratory of Public Health.
authors.forename: S
authors.initials: S
authors.lastname: Matsushita
authors.forename: N
authors.initials: N
authors.lastname: Konishi
authors.forename: Y
authors.initials: Y
authors.lastname: Yanagawa
authors.forename: A
authors.initials: A
authors.lastname: Kai
authors.forename: S
authors.initials: S
authors.lastname: Morozumi
authors.forename: H
authors.initials: H
authors.lastname: Igarashi
authors.forename: K
authors.initials: K
authors.lastname: Morita
authors.forename: M
authors.initials: M
authors.lastname: Kanamori
authors.forename: Y
authors.initials: Y
authors.lastname: Kudoh
mesh_terms: D004352:Drug Resistance, Microbial; D012764:Shigella sonnei / Q000302:isolation & purification*; D014041:Tokyo