title: Major hepatic resection without blood transfusion: experience with total vascular exclusion.
abstract: Thirty consecutive, major liver resections performed with total vascular exclusion in both non-cirrhotic and cirrhotic patients were analysed retrospectively. The patients' ages ranged from 6 months to 80 years. Ten were Asians and five had cirrhosis associated with chronic hepatitis B or C. There was no perioperative death and the mean hospital stay was 6 days for adults and 9.2 days for children. The average vascular exclusion or warm ischaemia time was 25 min (range 10-55 min) and the average intraoperative blood volume given was 275 mL (range 0-3000 mL) packed red blood cells. Sixty per cent required no intraoperative blood transfusion. The mean total bilirubin and aspartate aminotransferase were 1.0 mg/dL (range 0.3-2.3 mg/dL) and 84 IU/L (range 14-306 IU/L) when measured prior to discharge at postoperative day 4-7. In our experience, total vascular exclusion is invaluable in major or difficult liver resections, especially lesions adjacent to the hepatic veins and vena cava. It is associated with a low blood transfusion requirement and a low incidence of complications. It further obviates the need for dissection of the porta hepatis and its associated risks. Total vascular exclusion time of 30 min appears to be well tolerated, even in patients with compensated cirrhosis.
authors.affiliation: Department of Surgery, Stanford University School of Medicine, Stanford Asian Liver Center, California, USA. samso@stanford.edu
authors.forename: S K
authors.initials: SK
authors.lastname: So
authors.forename: H
authors.initials: H
authors.lastname: Monge
authors.forename: C O
authors.initials: CO
authors.lastname: Esquivel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002675:Child, Preschool; D006498:Hepatectomy / Q000379:methods*; D019694:Hepatitis B, Chronic / Q000150:complications; D019698:Hepatitis C, Chronic / Q000150:complications; D006801:Humans; D007223:Infant; D008103:Liver Cirrhosis / Q000601:surgery; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies