title: Stabilisation of medically refractory ventricular arrhythmia by intra-aortic balloon counterpulsation.
abstract: OBJECTIVE
  To review the efficacy of intra-aortic balloon counterpulsation (IABCP) in medically refractory ventricular arrhythmia.
  
  
  METHODS
  Retrospective analysis of the outcome of patients with ventricular arrhythmia treated with IABCP after transfer between 1992 and 1997.
  
  
  METHODS
  Tertiary cardiac referral centre.
  
  
  METHODS
  21 patients (mean age 58 years) who underwent IABCP for control of ventricular arrhythmia. All had significant left ventricular impairment (mean ejection fraction 28.6%); 18 had coronary artery disease.
  
  
  RESULTS
  Before IABCP, 10 patients had incessant monomorphic ventricular tachycardia and 11 had paroxysmal ventricular tachycardia and/or ventricular fibrillation (VT/VF). IABCP resulted in suppression of ventricular arrhythmia in 18 patients, of whom 13 were weaned from IABCP. After stabilisation of ventricular arrhythmia, 10 patients were maintained on medical treatment alone and one underwent endocardial resection. IABCP was maintained until cardiac transplantation in five patients. One patient had a fatal arrest before discharge and one died from progressive heart failure. IABCP failed to control ventricular arrhythmia in three patients and was subsequently discontinued. A cardiac assist device was employed in one of these until cardiac transplantation; the other two were eventually stabilised on medical treatment. Nineteen patients were discharged from hospital. Overall survival was 95% at mean follow up of 25.7 months.
  
  
  CONCLUSIONS
  IABCP can be an effective means of controlling refractory ventricular arrhythmia, allowing time for the institution of more definitive treatment.
authors.affiliation: Department of Cardiology, Harefield Hospital, Harefield, Middlesex UB9 6JH, UK.
authors.forename: G D
authors.initials: GD
authors.lastname: Fotopoulos
authors.forename: M J
authors.initials: MJ
authors.lastname: Mason
authors.forename: S
authors.initials: S
authors.lastname: Walker
authors.forename: N S
authors.initials: NS
authors.lastname: Jepson
authors.forename: D J
authors.initials: DJ
authors.lastname: Patel
authors.forename: A G
authors.initials: AG
authors.lastname: Mitchell
authors.forename: C D
authors.initials: CD
authors.lastname: Ilsley
authors.forename: V E
authors.initials: VE
authors.lastname: Paul
mesh_terms: D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000209:etiology / Q000628:therapy*; D015908:Counterpulsation / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000628:therapy; D012189:Retrospective Studies