Bombesin-like neuropeptides in nematodes.
This paper reports evidence of members of the bombesin-like peptide family in a number of nematodes, including Caenorhabditis, Panagrellus, Dirofilaria, Onchocerca, Brugia, Haemonchus, Ostertagia, Toxocara, and Ascaris. One of these (Ostertagia) secretes the bombesin-like material into its environment. Specific binding of gastrin-releasing peptide to the hypodermis consistent with the presence of receptors was demonstrated. These data suggest that this class of peptides may play an important role in nematode hypodermal physiology.
Huntington
M K
MK
Department of Microbiology, Michigan State University, East Lansing 48824, USA.
Geary
T G
TG
Mackenzie
C D
CD
Williams
J F
JF
D000818:Animals; D001665:Binding Sites; D001839:Bombesin / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism; D008856:Microscopy, Fluorescence; D009348:Nematoda / Q000737:chemistry*; D011863:Radioimmunoassay; D018004:Receptors, Bombesin / Q000032:analysis*
D018004:Receptors, Bombesin; D001839:Bombesin