title: [Long term evolution of the incapacity in schizophrenic patients in maintenance treatment with risperidone].
abstract: OBJECTIVE
  To determine the evolution of the degree of long term disability (8 months) in a group of schizophrenic outpatients undergoing monotherapy with risperidone. DESIGN, An observational multicentre study of 8 months follow up.
  
  
  METHODS
  354 patients with schizophrenic disorder (ICD-10).
  
  
  RESULTS
  Baseline, 2, 4 and 8 months.
  
  
  METHODS
  BPRS, CGI, UKU, WHO/DAS-S.
  
  
  RESULTS
  a significant decrease in both the global scores and in each of the 4 areas of disability. Improvement in disability depends to a large degree on the improvement of the disorder as shown on the BPRS and CGI. After 8 months, those patients with paranoid subtype and the less severe ones (BPRS and CGI) showed a considerably lesser degree of disability. The final level of disability (square root = 0,61) is narrowly related to the baseline level of disability, the 3 clusters of the final BPRS, the final CGI, gender and the subtype of schizophrenia.
authors.affiliation: Area de Psiquiatría,Universidad de Oviedo, Oviedo,Asturias, 33006,España.
authors.forename: J
authors.initials: J
authors.lastname: Bobes
authors.forename: M P
authors.initials: MP
authors.lastname: González
authors.forename: J
authors.initials: J
authors.lastname: Gibert
authors.forename: M
authors.initials: M
authors.lastname: Gutiérrez
authors.forename: M L
authors.initials: ML
authors.lastname: Herráiz
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D004185:Disability Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D018967:Risperidone / Q000627:therapeutic use*; D012559:Schizophrenia / Q000188:drug therapy*
chemical_list: D014150:Antipsychotic Agents; D018967:Risperidone
vernacular_title: Evolución a largo plazo de la discapacidad en pacientes esquizofrénicos en tratamiento de mantenimiento con risperidona.