title: The benefit of Beam's eye view based 3D treatment planning for cervical cancer.
abstract: OBJECTIVE
  The aim of this study was to evaluate the possibility of Beam's eye view (BEV) based three dimensional (3D) treatment planning, to reduce portions of organs at risk included in the treated volume without increasing the risk of geographical miss in external beam therapy of cervical cancer.
  
  
  METHODS
  Three dimensional dose distribution of BEV based 3D treatment plans was compared to the 3D dose distribution derived from a four-field-box-technique using standard portals. A total of 20 patients with cervical cancer stage FIGO IIB and FIGO IIIB was included. Dose distribution in the target volumes and in the organs at risk of BEV based treatment planning, was compared to the dose distribution of the standard field technique using dose-volume-histograms.
  
  
  RESULTS
  In 4/20 patients (20%) a geographical miss at the cervix uteri was observed for the standard field technique. The BEV based treatment planning resulted in an adequate coverage of target volume and additionally in a reduction of portions of bladder and bowel volume included in the treated volume (-13.5, -10%). In contrast the BEV based technique resulted in an increase of portions of the rectum volume included in the treated volume compared to standard portals due to a shift of the rectum by the enlarged cervix uteri from its posterior to a lateral position. An overall 7% reduction of treated volume was observed, although the maximum width of lateral fields increased for the BEV technique. Moreover, we have found a remarkable impact of bladder fillings on the amount of bowel and bladder volume included in the treated volume.
  
  
  CONCLUSIONS
  BEV based 3D treatment planning for external beam therapy of cervical cancer offers a possibility to avoid geographical miss of part of the CTV with reduced portions of bladder and bowel volume included in the treated volume.
authors.affiliation: Department of Radiotherapy and Radiobiology, University Hospital of Vienna, Austria.
authors.forename: N
authors.initials: N
authors.lastname: Gerstner
authors.forename: S
authors.initials: S
authors.lastname: Wachter
authors.forename: T H
authors.initials: TH
authors.lastname: Knocke
authors.forename: C
authors.initials: C
authors.lastname: Fellner
authors.forename: A
authors.initials: A
authors.lastname: Wambersie
authors.forename: R
authors.initials: R
authors.lastname: Pötter
mesh_terms: D005260:Female; D006801:Humans; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*