Blood transfusion-acquired hemoglobin C.
Unexpected and confusing laboratory test results can occur if a blood sample is inadvertently collected following a blood transfusion. A potential for transfusion-acquired hemoglobinopathy exists because heterozygous individuals show no significant abnormalities during the blood donor screening process. Such spurious results are infrequently reported in the medical literature. We report a case of hemoglobin C passively transferred during a red blood cell transfusion. The proper interpretation in our case was assisted by calculations comparing expected hemoglobin C concentration with the measured value. A review of the literature on transfusion-related preanalytic errors is provided.
Suarez
A A
AA
Department of Pathology, St Louis University, St Louis, MO, USA.
Polski
J M
JM
Grossman
B J
BJ
Johnston
M F
MF
D001797:Blood Protein Electrophoresis; D017707:Erythrocyte Transfusion / Q000009:adverse effects*; D005260:Female; D006444:Hemoglobin C / Q000032:analysis*; D006801:Humans; D008875:Middle Aged
D006444:Hemoglobin C