Increasing fluoroquinolone resistance in salmonella serotypes in Finland during 1995-1997.
Antimicrobial resistance trends were examined for 811 salmonella isolates from humans collected in Finland during 1995-1997. The material was divided into domestic and foreign isolates according to the origin of infection. A total of 2.3% of the 387 domestic and 7.8% of the 424 foreign isolates were quinolone-resistant (P < 0.001). Among the domestic isolates we detected an emergence of ciprofloxacin resistance (MIC > or = 0.25 mg/L) with the proportion of resistant isolates increasing from 0 to 2.2% (P = 0.2). Among the foreign isolates this increase was even more dramatic, from 2.0% to 8.4% (P = 0.037) during the study period.
Hakanen
A
A
Antimicrobial Research Laboratory, National Public Health Institute, Turku, Finland. antti.hakanen@utu.fi
Siitonen
A
A
Kotilainen
P
P
Huovinen
P
P
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D005387:Finland; D006801:Humans; D008137:Longitudinal Studies; D008826:Microbial Sensitivity Tests; D012475:Salmonella / Q000145:classification / Q000187:drug effects* / Q000502:physiology; D012703:Serotyping
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D002939:Ciprofloxacin