title: Domains of social communication handicap in autism spectrum disorder.
abstract: OBJECTIVE
  To investigate whether specific "social communication" handicaps could be identified in autism spectrum disorder using the Autism Diagnostic Observation Schedule and to compare the results with those found in a previous factor-analysis study using the Autism Diagnostic Interview-Revised.
  
  
  METHODS
  All subjects were evaluated with both instruments. J.R. and P.E.T. independently diagnosed autism, Asperger's disorder, or pervasive developmental disorder--not otherwise specified in 51 children. Items from the Autism Diagnostic Observation Schedule that represented social communication behaviors were factor-analyzed.
  
  
  RESULTS
  Three factors were identified: joint attention, affective reciprocity, and theory of mind. These are the same social communication domains that were identified in the previous study.
  
  
  CONCLUSIONS
  These 3 social communication domains have been discussed in the literature regarding normal development and in previous research on autism spectrum disorders. If these domains are replicated in larger sample sizes, they could be used to monitor the results of pharmacological and psychotherapeutic interventions in autism spectrum disorders.
authors.affiliation: Department of Psychiatry, University of Louisville School of Medicine, KY, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Robertson
authors.forename: P E
authors.initials: PE
authors.lastname: Tanguay
authors.forename: S
authors.initials: S
authors.lastname: L'Ecuyer
authors.forename: A
authors.initials: A
authors.lastname: Sims
authors.forename: C
authors.initials: C
authors.lastname: Waltrip
mesh_terms: D000293:Adolescent; D001321:Autistic Disorder / Q000145:classification / Q000523:psychology*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003144:Communication Barriers; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D019370:Observation / Q000379:methods; D011594:Psychometrics / Q000379:methods*; D012720:Severity of Illness Index; D012919:Social Behavior