title: Co-receptors on B lymphocytes.
abstract: Co-receptors have been shown to regulate the antigen-receptor signaling threshold for B cell responses by modulating the activation of signaling molecules that are essential for transmitting a signal through the antigen-receptor. Co-receptors appear to modulate the signaling threshold for B cell tolerance distinctly from that for B cell activation.
authors.affiliation: Department of Immunology, Medical Research Institute, Tokyo Medical andDental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan. tsubata.imm@mri.tmd.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Tsubata
mesh_terms: D000818:Animals; D015703:Antigens, CD / Q000378:metabolism; D018941:Antigens, CD19 / Q000378:metabolism; D000944:Antigens, Differentiation, B-Lymphocyte / Q000378:metabolism; D001402:B-Lymphocytes / Q000276:immunology*; D015815:Cell Adhesion Molecules; D006801:Humans; D007108:Immune Tolerance; D037102:Lectins; D008213:Lymphocyte Activation; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D011947:Receptors, Antigen, B-Cell / Q000378:metabolism*; D017464:Receptors, Complement 3d / Q000378:metabolism; D017452:Receptors, IgG / Q000378:metabolism; D051918:Sialic Acid Binding Ig-like Lectin 2; D015398:Signal Transduction / Q000276:immunology
chemical_list: D015703:Antigens, CD; D018941:Antigens, CD19; D000944:Antigens, Differentiation, B-Lymphocyte; C497867:CD22 protein, human; C064228:CD72 protein, human; D015815:Cell Adhesion Molecules; D037102:Lectins; D011947:Receptors, Antigen, B-Cell; D017464:Receptors, Complement 3d; D017452:Receptors, IgG; D051918:Sialic Acid Binding Ig-like Lectin 2; D010744:Phosphoric Monoester Hydrolases