title: [A priority mission: prevention, early detection, identification of risk factors of progression of chronic renal insufficiency].
abstract: The prevalence of chronic renal failure is continuously increasing. The reasons are the lengthening life expectancy of the general population, the increasing age of the patient population benefitting from renal replacement therapy and the growing number of vascular and diabetic nephropathies leading to end-stage renal disease. The financial burden of treating renal failure is considerable, estimated at nearly 2 percent of the national health budget. A priority for French departments of nephrology is to initiate and participate in epidemiological studies on renal failure in order to eradicate the present pitfalls: lack of exhaustiveness and non-validation of information. The need is to create networks for patient care and management, grouping specialists such as cardiologists, diabetologists, rheumatologists and gerontologists, who face the problems stemming from renal failure, for early identification of problems, in order to apply appropriate measures to slow disease progression and to initiate renal management at the optimal time. Active participation in research is indispensable, not only in multicentric studies but also in "nephrosurveillance" and for development of guidelines for good clinical practice and good prescription practice. Many tools are available for undertaking varied experimental research. This research can lead to identification of the cellular and molecular mechanisms underlying nephron destruction and to development of effective strategies to slow or halt the progression of lesions. Identification of genetic factors that favor the appearance or progression of renal failure is in its early stages and will continue to develop. All these efforts require communication and teaching. A last point: the need to revamp hospital organization to better respond to the needs of patients requiring only a few hours in specialized units.
authors.affiliation: CHU de Rouen.
authors.forename: J P
authors.initials: JP
authors.lastname: Fillastre
mesh_terms: D018450:Disease Progression; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D015995:Prevalence; D012307:Risk Factors
vernacular_title: Une mission prioritaire: la prévention, le dépistage précoce, l'identification des facteurs de risque de progression de l'insuffisance rénale chronique.