title: Estimation and detection of myocardial tags in MR image without user-defined myocardial contours.
abstract: Magnetic resonance (MR) tagging has been shown to be a useful technique for noninvasively measuring the deformation of an in vivo heart. An important step in analyzing tagged images is the identification of tag lines in each image of a cine sequence. Most existing tag identification algorithms require user defined myocardial contours. Contour identification, however, is time consuming and requires a considerable amount of user intervention. In this paper, a new method for identifying tag lines, which we call the ML/MAP method, is presented that does not require user defined myocardial contours. The ML/MAP method is composed of three stages. First, a set of candidate tag line centers is estimated across the entire region-of-interest (ROI) with a snake algorithm based on a maximum-likelihood (ML) estimate of the tag center. Next, a maximum a posteriori (MAP) hypothesis test is used to detect the candidate tag centers that are actually part of a tag line. Finally, a pruning algorithm is used to remove any detected tag line centers that do not meet a spatio-temporal continuity criterion. The ML/MAP method is demonstrated on data from ten in vivo human hearts.
authors.affiliation: Department of Electrical and Computer Engineering, Auburn University, AL 36849, USA.
authors.forename: T S
authors.initials: TS
authors.lastname: Denney
mesh_terms: D000465:Algorithms; D006321:Heart / Q000033:anatomy & histology*; D006801:Humans; D016013:Likelihood Functions; D008279:Magnetic Resonance Imaging; D008962:Models, Theoretical