Molecular mechanisms of yeast longevity.
The genetic analysis of yeast longevity has illuminated the underlying molecular mechanisms of aging that invoke the importance of metabolic regulation, genetic stability and stress resistance in determination of life span. The RAS genes have emerged as important modulators of life-maintenance processes and of life span itself.
Jazwinski
S M
SM
Dept of Biochemistry and Molecular Biology, Louisiana State University Medical Center, New Orleans, LA 70112, USA. sjazwi@lsumc.edu
D015966:Gene Expression Regulation, Fungal; D011905:Genes, ras / Q000502:physiology*; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000254:growth & development* / Q000502:physiology