title: Evidence for the collateral innervation of the esophagus and the heart from neurons in the compact formation of the nucleus ambiguus of the rat.
abstract: We investigated whether the heart receives collateral projections from the neurons which innervate the esophagus with a retrograde double-labeling method using two fluorescent tracers. Following injections of True Blue (TB) into the esophagus and Diamidino Yellow (DY) into the heart, about 21.9% of the labeled esophageal motoneurons in the compact formation of the nucleus ambiguus (AmC) were retrogradely double labeled. No single-labeled cardiac motoneurons were found in the AmC. The present results provide anatomical substrates for the esophagocardiac reflex.
authors.affiliation: Department of Anatomy, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan. cheng@med1.kufm.kagoshima-u.ac.jp
authors.forename: S B
authors.initials: SB
authors.lastname: Cheng
authors.forename: T
authors.initials: T
authors.lastname: Hayakawa
authors.forename: S
authors.initials: S
authors.lastname: Kuchiiwa
authors.forename: S
authors.initials: S
authors.lastname: Maeda
authors.forename: H
authors.initials: H
authors.lastname: Ito
authors.forename: M
authors.initials: M
authors.lastname: Seki
authors.forename: S
authors.initials: S
authors.lastname: Nakagawa
mesh_terms: D000578:Amidines; D000818:Animals; D001572:Benzofurans; D004947:Esophagus / Q000294:innervation*; D005456:Fluorescent Dyes; D006321:Heart / Q000294:innervation*; D008526:Medulla Oblongata / Q000166:cytology / Q000502:physiology*; D009046:Motor Neurons / Q000502:physiology; D009434:Neural Pathways / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D000578:Amidines; D001572:Benzofurans; D005456:Fluorescent Dyes; C038675:true blue; C037945:diamidino yellow