Hepatitis B virus surface antigen (HBsAg) and antibody (anti-HBs) forming immune complexes in fulminant hepatitis.
This paper reports an unusual pattern of serological HBV markers and the presence of HBsAg/anti-HBs immune complexes in serum samples from two patients with fulminant hepatitis from the Brazilian Western Amazon Basin. The diagnosis was made by both serologic tests and demonstration of antigen/antibody complexes by transmission electron microscopy. Concurrent Delta virus superinfection is also discussed.
Soares
M C
MC
Instituto Evandro Chagas, Fundação Nacional de Saúde do Ministério da Saúde, Belém, PA, Brasil.
Bensabath
G
G
Cartágenes
P R
PR
Alves
M M
MM
Silveira
F A
FA
Linhares
A C
AC
D000936:Antigen-Antibody Complex / Q000032:analysis*; D015415:Biomarkers; D002648:Child; D017809:Fatal Outcome; D005260:Female; D006501:Hepatic Encephalopathy / Q000276:immunology*; D006510:Hepatitis B Antibodies / Q000032:analysis*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D003698:Hepatitis Delta Virus / Q000302:isolation & purification; D006801:Humans; D008297:Male
D000936:Antigen-Antibody Complex; D015415:Biomarkers; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens