title: [Bronchofiberscope and catheter intervention in treatment of multi-drug resistant pulmonary tuberculosis].
abstract: OBJECTIVE
  To evaluate the clinical value of bronchofiberscope and catheter intervention in treatment of multi-drug resistant pulmonary tuberculosis.
  
  
  METHODS
  Forty-eight patients with multi-drug resistant pulmonary tuberculosis were treated by injecting ofloxacin and amikacin through bronchofiberscope and catheter in addition to chemotherapy, while forty controls were treated by chemotherapy only.
  
  
  RESULTS
  At the end of the treatment, the sputum conversion rate was 92%, radiographic improvement rate 96% and cavity closing rate 27% in the treatment group, all of which were higher than the controls (63%, 58% and 10% respectively) (P < 0.01-0.05). No complication and obvious adverse reaction were observed.
  
  
  CONCLUSIONS
  The efficacy of bronchofiberscope and catheter intervention in addition to chemotherapy is better than only chemotherapy in treatment of multi-drug resistant pulmonary tuberculosis.
authors.affiliation: Department of Pulmonary Medicine, 175th Hospital, P.L.A., Zhangzhou.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: H
authors.initials: H
authors.lastname: Qian
authors.forename: M
authors.initials: M
authors.lastname: Chen
mesh_terms: D000328:Adult; D000583:Amikacin / Q000008:administration & dosage*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D001999:Bronchoscopy; D002406:Catheterization, Peripheral; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000008:administration & dosage*; D018088:Tuberculosis, Multidrug-Resistant / Q000628:therapy*; D014397:Tuberculosis, Pulmonary / Q000628:therapy*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000583:Amikacin; D015242:Ofloxacin