title: Recurrent cardiocirculatory arrest after kidney transplantation related to intravenous methylprednisolone bolus therapy.
abstract: BACKGROUND
  Intravenous bolus therapy with steroids is often used in standard immunosuppression initially after organ transplantation and to treat acute graft rejection. Although this regimen in generally is safe, severe adverse effects can occur.
  
  
  METHODS
  This letter gives a picture of the eventful clinical course of a patient with preexisting heard problems after renal transplantation.
  
  
  RESULTS
  This case report proves lethal cardiopulmonary complications closely related to the recurrent intravenous administration of methylprednisolone in a risk patient.
  
  
  CONCLUSIONS
  Severe side effects after the application of high-dose steroids are possible. If risk patients are identified, steroid bolus therapy should be avoided or, if not possible, should only be done under close monitoring.
authors.forename: M
authors.initials: M
authors.lastname: Schult
authors.forename: D
authors.initials: D
authors.lastname: Löhmann
authors.forename: W
authors.initials: W
authors.lastname: Knitsch
authors.forename: E R
authors.initials: ER
authors.lastname: Kuse
authors.forename: B
authors.initials: B
authors.lastname: Nashan
mesh_terms: D006084:Graft Rejection / Q000517:prevention & control; D006323:Heart Arrest / Q000139:chemically induced / Q000209:etiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007275:Injections, Intravenous; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000276:immunology; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000627:therapeutic use*; D008875:Middle Aged
chemical_list: D007166:Immunosuppressive Agents; D008775:Methylprednisolone