title: Rotation-induced conditioned rejection in the taste reactivity test.
abstract: The taste reactivity test was used to evaluate the ability of motion sickness to produce conditioned rejection reactions, a putative measure of nausea in rats. Following three conditioning trials, rats displayed conditioned rejection reactions during an intraoral infusion of a rotation-paired saccharin solution. This is the first demonstration of conditioned rejection produced with a non-pharmacological emetic agent and provides support that the conditioned rejection reaction may serve as a rat model of nausea.
authors.affiliation: Department of Psychology, Wilfrid Laurier University, Waterloo, Ontario, Canada.
authors.forename: N
authors.initials: N
authors.lastname: Cordick
authors.forename: L A
authors.initials: LA
authors.lastname: Parker
authors.forename: K P
authors.initials: KP
authors.lastname: Ossenkopp
mesh_terms: D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D003216:Conditioning, Operant / Q000502:physiology*; D008297:Male; D009041:Motion Sickness / Q000503:physiopathology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012399:Rotation; D012439:Saccharin; D013649:Taste / Q000502:physiology*
chemical_list: D012439:Saccharin