title: [Revascularization of isolated bone in dogs].
abstract: To elucidate whether the revascularization of isolated bone could be built and what is the influence on osteogenesis. We studied eighteen adult mongrel dogs and divided them into three groups in random. Osteotomy was performed on the two condyles of the tibia and the periosteum was removed. Two pieces of silica gel sheet were inserted into the gaps of osteotomy to block blood supply, then immobolization was made. The vascular bundle of anterior tibia artery and vein was separated and ligated. Subsequently, it was directly implanted into the isolated bar of tibia (Group A, n = 7). It implanted after holes were made (Group B, n = 7). Controls (Group C, n = 4) were observed without transplantation. The animals were investigated by angiography, casting mode of vascular net, mass and histologic and electromircroscopeic examination at different intervals. Osteonecrosis was occurred in the tested bone because of ischemia. The proliferation of vascular net was occurred and prosperous osteogenesis was found in the medullary cavity after transplanting a vascular bundle. Revascularization of necrotic bone was able to be established by transplanting a vascular bundle. Both membranous and lndochondral ossification play an important role in osteogenesis.
authors.affiliation: Department of Pediatric Surgery, General Hospital, People's Liberation Army, Beijing.
authors.forename: B
authors.initials: B
authors.lastname: Men
authors.forename: C
authors.initials: C
authors.lastname: Ma
authors.forename: Z
authors.initials: Z
authors.lastname: Li
mesh_terms: D000818:Animals; D004285:Dogs; D005599:Fractures, Ununited / Q000601:surgery*; D018919:Neovascularization, Physiologic; D010012:Osteogenesis; D010020:Osteonecrosis / Q000601:surgery; D013977:Tibia / Q000098:blood supply* / Q000293:injuries / Q000601:surgery; D016909:Tibial Arteries / Q000637:transplantation*; D014680:Veins / Q000637:transplantation