title: [Toxicity and radiation protective properties of 2(3)-guanidinoalkanethiols: structure-activity].
abstract: In experiments with mice radioprotective properties and toxicity of 2(3)-guanidinoalkanethiols were investigated by exposure to gamma-irradiation in the dose of 6.4 Gy. The obtained results allow to find an association between radioprotective activity of 2(3)-guanidinoalkanethiol compounds and their structure and toxicity.
authors.affiliation: Moscow State University, Department of Chemistry. mandrug@radio.chem.msu.ru
authors.forename: A A
authors.initials: AA
authors.lastname: Mandrugin
authors.forename: V M
authors.initials: VM
authors.lastname: Fedoseev
authors.forename: O V
authors.initials: OV
authors.lastname: Dubovaia
authors.forename: A A
authors.initials: AA
authors.lastname: Rodiunin
authors.forename: M M
authors.initials: MM
authors.lastname: Konstantinova
authors.forename: G V
authors.initials: GV
authors.lastname: Dontsova
mesh_terms: D000818:Animals; D006146:Guanidines / Q000494:pharmacology*; D007928:Lethal Dose 50; D051379:Mice; D011837:Radiation-Protective Agents / Q000494:pharmacology* / Q000633:toxicity; D013329:Structure-Activity Relationship
chemical_list: D006146:Guanidines; D011837:Radiation-Protective Agents
vernacular_title: Toksichnost' i protivoluchevye svoĭstva 2(3)-guanidinoalkantiolov: struktura-aktivnost'.