Successful treatment of severe muscle necrosis with intravenous immunoglobulin.
Intravenous immunoglobulin (IVIG) is an effective treatment for a range of conditions believed to have an autoimmune basis, including inflammatory muscle disease. We describe a patient with muscle disease characterized by severe necrosis without clinical or biopsy evidence of inflammation or vasculitis, who responded to treatment with IVIG.
McRorie
E
E
Rheumatic Diseases Unit, Western General Hospital, Edinburgh, United Kingdom.
King
M
M
Richmond
R
R
Smith
G
G
Jobanputra
P
P
Nuki
G
G
D001706:Biopsy; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology*; D009336:Necrosis; D017285:Polymyositis / Q000097:blood / Q000188:drug therapy* / Q000473:pathology*
D016756:Immunoglobulins, Intravenous; D003402:Creatine Kinase