[Importance and limitations of the validation of functional MRI of motor function and language using preoperative cortical stimulation].
This chapter describes and discusses the value of the localization of functional areas obtained from functional MRI in brain tumor cases. Correlation method is cortical brain mapping by intraoperative stimulation. The experience reported here is focused on the study of motricity and language.


METHODS
Twenty two patients with tumors of the rolandic region (n = 16) or in the temporal lobe (n = 6) underwent functional MR mapping and subsequently cortical mapping before tumor resection. The tasks chosen were a flexion and extension of the fingers or a naming task. We used 3D reconstructed images of the surface of the brain to assess intra and post operatively the functional MRI and stimulation data.


RESULTS
For the motor correlation, in each case, the results of direct cortical mapping matched those obtained with functional MRI, both positively and negatively, although the extent of the functional activations was larger than the area required to elicit the corresponding movement during intraoperative brain mapping. For the language correlation and for the task chosen, only the results of the precentral areas matched those of functional MRI.


CONCLUSIONS
Functional MRI can be used preoperatively to assess motor functional area in patients with rolandic tumors. More studies are needed to validate intraoperatively the language areas and the real extent of functional MRI activations. Finally, the observed discrepancy between functional MRI and cortical stimulation is likely due to the rather profound differences between both techniques, in terms of neurophysiology, practical applications and statistical analysis.
Roux
F E
FE
Service de Neuroradiologie, CHU Purpan, Toulouse, France.
Boulanouar
K
K
Ibarrola
D
D
Tremoulet
M
M
Henry
P
P
Manelfe
C
C
Berry
I
I
D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000601:surgery; D004558:Electric Stimulation; D005260:Female; D006801:Humans; D007430:Intraoperative Care / Q000379:methods*; D007802:Language; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D015203:Reproducibility of Results
Intérêt et limites de la validation de l'irm fonctionnelle de la motricité et du langage par la stimulation corticale peropératoire.