A new method for continuous tonometric pCO2 measurement--in vitro studies.
The available methods for tonometric pCO2 measurement only provide the possibility of performing intermittent registrations. A new method allowing continuous tonometric pCO2 measurement has been developed and tested in an in vitro model. A standard tonometer for intestinal pCO2 measurement was modified to allow continuous perfusion of the balloon with physiological saline solution in a closed system. The pCO2 in the system was determined in a specially constructed measurement chamber with a TCM20 percutaneous pCO2 monitor. In this in vitro model the tonometer balloon was placed in a saline bath with a constant pCO2 concentration and the measurements from the closed circulating system were compared with those obtained from a standard tonometer placed in the same bath. In 8 and 24 h experiments the circulating system measured the pCO2 value as accurately and reliably as traditional tonometry. This study indicates that the new method makes continuous monitoring of pCO2 possible.
Fröjse
R
R
Department of Surgery, University Hospital of Umeå, Sweden.
Arnerlöv
C
C
Hedberg
B
B
Haggström
M
M
Bäcklund
T
T
Lindahl
O
O
Angquist
K A
KA
D002138:Calibration; D002245:Carbon Dioxide / Q000032:analysis*; D002404:Catheterization; D017091:Colitis, Ischemic / Q000175:diagnosis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000378:metabolism*; D008365:Manometry / Q000295:instrumentation / Q000379:methods*; D012680:Sensitivity and Specificity; D013997:Time Factors
D002245:Carbon Dioxide