title: [Chronic eosinophilic pneumonia associated with rheumatoid arthritis].
abstract: We encountered a 45-year-old woman with chronic eosinophilic pneumonia associated with rheumatoid arthritis. In May 1997, she was given a diagnosis of rheumatoid arthritis and prescribed non-steroidal anti-inflammatory drugs. After a month, she visited our hospital because of fever and cough. A chest roentgenogram and computed tomographic scan on first admission revealed peripheral infiltrative shadows in the upper fields of both lungs. Approximately 30% of peripheral blood cells were eosinophils. Furthermore eosinophils were elevated in bronchoalveolar lavage fluid and transbronchial lung biopsy specimens. A conclusive diagnosis of chronic eosinophilic pneumonia was made on these grounds. The patient responded well to steroid treatment, but was readmitted a week later because of worsening joint pain and skin eruptions in the lower extremities of both legs. A skin biopsy showed perivascular and interstitial eosinophil infiltration. The combination of steroids, a disease modifying anti-rheumatic drug, and a non-steroidal anti-inflammatory drug proved to be effective.
authors.affiliation: Takamatu Hospital, Kagawa, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Saito
authors.forename: Y
authors.initials: Y
authors.lastname: Mori
authors.forename: T
authors.initials: T
authors.lastname: Maeta
authors.forename: K
authors.initials: K
authors.lastname: Oonishi
authors.forename: H
authors.initials: H
authors.lastname: Koui
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008875:Middle Aged; D011657:Pulmonary Eosinophilia / Q000188:drug therapy / Q000209:etiology*