Gene therapy as a therapeutic intervention for vascular disease.
Gene therapy for the treatment of many medical problems, including vascular disease, has become the subject of increasing discussion in both the scientific literature and the national press over the past decade. This review will examine the history and current status of gene therapy for vascular proliferative disorders and advanced chronic peripheral and cardiac ischemia.
Meyerson
S L
SL
Department of Surgery, University of Chicago, Illinois, IL 60637, USA.
Schwartz
L B
LB
D017130:Angioplasty; D019917:Blood Vessel Prosthesis Implantation; D002908:Chronic Disease; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods*; D005822:Genetic Vectors / Q000627:therapeutic use; D006801:Humans; D018919:Neovascularization, Physiologic; D016491:Peripheral Vascular Diseases / Q000235:genetics / Q000628:therapy*; D016879:Salvage Therapy