title: Electrochemical studies of cytochrome c disulfide at gold electrodes.
abstract: The electrochemistry of disulfide in cytochrome c on gold electrodes was reported. The observed electrochemical response was used to explain why the electrochemical reaction of cytochrome c is irreversible at gold electrodes. Disulfide bonds in cytochrome c were strongly adsorbed onto the surface of gold electrodes and caused slow rate of electron transfer of the heme group. It was found that the presence of disulfides in cytochrome c was responsible for the lack of electrochemical response of the heme group on a gold electrode. The mechanisms for this effect were studied using electrochemistry and photoelectron spectroscopy.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Yamaguchi University, Ube, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhou
authors.forename: T
authors.initials: T
authors.lastname: Nagaoka
authors.forename: G
authors.initials: G
authors.lastname: Zhu
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D000818:Animals; D000965:Antimony; D002244:Carbon; D003574:Cytochrome c Group / Q000737:chemistry*; D004220:Disulfides / Q000737:chemistry; D004563:Electrochemistry; D004566:Electrodes; D005898:Glass; D006046:Gold; D006108:Graphite; D006418:Heme / Q000737:chemistry; D006736:Horses; D066298:In Vitro Techniques; D010084:Oxidation-Reduction; D010984:Platinum
chemical_list: D000596:Amino Acids; D003574:Cytochrome c Group; D004220:Disulfides; D006418:Heme; D010984:Platinum; D002244:Carbon; D006046:Gold; D006108:Graphite; D000965:Antimony