title: Retroviral vectors pseudotyped with lymphocytic choriomeningitis virus.
abstract: Pseudotyping can improve retroviral vector stability and transduction efficiency. Here, we describe a novel pseudotype of murine leukemia virus packaged with lymphocytic choriomeningitis virus (LCMV). This pseudotype was stable during ultracentrifugation and infected several cell lines from different species. Moreover, LCMV glycoproteins were not cell toxic.
authors.affiliation: Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie an der Universität Hamburg, 20251 Hamburg, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Miletic
authors.forename: M
authors.initials: M
authors.lastname: Bruns
authors.forename: K
authors.initials: K
authors.lastname: Tsiakas
authors.forename: B
authors.initials: B
authors.lastname: Vogt
authors.forename: R
authors.initials: R
authors.lastname: Rezai
authors.forename: C
authors.initials: C
authors.lastname: Baum
authors.forename: K
authors.initials: K
authors.lastname: Kühlke
authors.forename: F L
authors.initials: FL
authors.lastname: Cosset
authors.forename: W
authors.initials: W
authors.lastname: Ostertag
authors.forename: H
authors.initials: H
authors.lastname: Lother
authors.forename: D
authors.initials: D
authors.lastname: von Laer
mesh_terms: D000818:Animals; D000956:Antigens, Viral; D016466:CHO Cells; D002460:Cell Line; D006224:Cricetinae; D005822:Genetic Vectors / Q000502:physiology*; D006023:Glycoproteins / Q000096:biosynthesis / Q000235:genetics*; D006801:Humans; D009052:Leukemia Virus, Murine / Q000502:physiology*; D008217:Lymphocytic choriomeningitis virus / Q000235:genetics; D014407:Tumor Cells, Cultured; D014764:Viral Proteins
chemical_list: D000956:Antigens, Viral; D006023:Glycoproteins; D014764:Viral Proteins; C115679:glycoprotein peptide, Lymphocytic choriomeningitis virus