title: [Effect of cyclic AMP on the excitation and response of command neurons responsible for the snail defensive behavior caused by sensory stimulation].
abstract: Extraneuronal application of db-cAMP or intraneuronal injection of cAMP were found to increase the neural membrane excitability and synaptic facilitation in neural responses to sensory stimulation of Lpl1 and Rpl1 neurones. The db-cAMP exerted no effects on neural responses to tactile stimulation of the snail foot or mantle. The intraneuronal injection of cAMP produced synaptic facilitation only in neural responses to quinine application to the snail head. The findings suggest the cAMP selective involvement in postsynaptic mechanisms of inducing the long-term facilitation transient stage.
authors.affiliation: P. K. Anokhin Institute of Normal Physiology, Moscow, Russia.
authors.forename: V P
authors.initials: VP
authors.lastname: Nikitin
authors.forename: S A
authors.initials: SA
authors.lastname: Kozyrev
mesh_terms: D000818:Animals; D003994:Bucladesine / Q000494:pharmacology; D002462:Cell Membrane / Q000502:physiology; D000242:Cyclic AMP / Q000494:pharmacology / Q000502:physiology*; D004594:Electrophysiology; D004924:Escape Reaction / Q000502:physiology*; D006372:Helix, Snails; D009473:Neuronal Plasticity / Q000502:physiology; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D009619:Nociceptors / Q000502:physiology; D010812:Physical Stimulation; D012701:Serotonin / Q000494:pharmacology / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology
chemical_list: D012701:Serotonin; D003994:Bucladesine; D000242:Cyclic AMP
vernacular_title: Deĭstvie tsAMF na vozbudimost' i otvety komandnykh neĭronov oboronitel'nogo povedeniia vinogradnoĭ ulitki, vyzvannye sensornymi razdrazheniiami.