title: Aggressive versus conservative therapy in unstable angina.
abstract: In patients with unstable angina, non-Q-wave, and Q-wave myocardial infarction, atherosclerotic plaque rupture leads to a variable amount of platelet adhesion and aggregation, vasoconstriction, and partially or totally occlusive thrombus formation. This article focuses on the role of aggressive (routine angiography and revascularization) versus conservative (maximal medical therapy, with catheterization and revascularization reserved for those with spontaneous or provable ischemia) management of the patient with unstable angina.
authors.affiliation: Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Lange
authors.forename: L D
authors.initials: LD
authors.lastname: Hillis
mesh_terms: D000789:Angina, Unstable / Q000097:blood / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D006801:Humans; D011379:Prognosis; D015996:Survival Rate; D015912:Thrombolytic Therapy; D016896:Treatment Outcome; D019210:Troponin I / Q000097:blood
chemical_list: D019210:Troponin I