[Regulation of intracellular CoA pool as one of approaches to correction of metabolic disorders].
The problems of biosynthesis of coenzyme A, its transport into the mitochondria, and compartmentalization in mammalian cells have been reviewed. Co A pool structure in liver cells and the in myocardium under different pathobiochemical conditionsis discussed. Experimental data which have now been accumulated can be used as a basis for correction of the metabolic disturbances of different etiology.
Sheĭbak
V M
VM
Grodno State Medical Institute, Belarus, Grodno.
D000818:Animals; D001692:Biological Transport; D002451:Cell Compartmentation; D003065:Coenzyme A / Q000096:biosynthesis* / Q000378:metabolism; D006801:Humans; D008659:Metabolic Diseases / Q000201:enzymology*
D003065:Coenzyme A
Reguliatsiia vnutrikletochnoĭ struktury fonda KoA kak odin iz podkhodov v korrektsii metabolicheskikh narusheniĭ.