title: Genetic population structure of two African-Ecuadorian communities of Esmeraldas.
abstract: The genetic structure of two African-Ecuadorian communities, Rio Cayapas and Viche (Esmeraldas province, northwest Ecuador), was studied on the basis of ACP1, ADA, AK1, CA2, ESD, GLO1, G6PD, PGD, and PGM1 subtypes and thermostability, PGM2, HBbeta, F13A, F13B, ORM1, AHSG, C6, C7, and APOC2 gene frequency, and migration data on 255 individuals. The fixation index of Wright (F(ST)), correspondence, and genetic distance analysis were applied to compare the genetic relationships between these communities and other American populations of African ancestry. F(ST) values from the migration data and surname origins suggest that Rio Cayapas is genetically more isolated and shows less mobility and admixture than does Viche. The genetic admixture estimates indicate a large contribution of African genes to the gene pool of both communities (74.3% to 58.4%), whereas the proportion of the Amerindian component differs significantly (14.5% in Rio Cayapas to 27.6% in Viche).
authors.affiliation: Department of Biology, University of Rome Tor Vergata, Italy. martine@uniroma2.it
authors.forename: C
authors.initials: C
authors.lastname: Martínez-Labarga
authors.forename: O
authors.initials: O
authors.lastname: Rickards
authors.forename: R
authors.initials: R
authors.lastname: Scacchi
authors.forename: R M
authors.initials: RM
authors.lastname: Corbo
authors.forename: G
authors.initials: G
authors.lastname: Biondi
authors.forename: J A
authors.initials: JA
authors.lastname: Peña
authors.forename: C
authors.initials: C
authors.lastname: Varas de Vieira
authors.forename: A E
authors.initials: AE
authors.lastname: Guevara
authors.forename: M S
authors.initials: MS
authors.lastname: Santurino
authors.forename: G F
authors.initials: GF
authors.lastname: de Stefano
mesh_terms: D000349:Africa / Q000208:ethnology; D044383:Black People / Q000235:genetics*; D003710:Demography; D004484:Ecuador; D004641:Emigration and Immigration; D004798:Enzymes / Q000235:genetics; D005006:Ethnicity / Q000235:genetics; D005260:Female; D005787:Gene Frequency; D005788:Gene Pool; D006801:Humans; D008297:Male; D010641:Phenotype; D010802:Phylogeny; D011506:Proteins / Q000235:genetics
chemical_list: D004798:Enzymes; D011506:Proteins