title: Ultrasound-induced temperature increase in guinea-pig fetal brain in utero: third-trimester gestation.
abstract: Temperature increase was measured at various depths in the brain of living fetal guinea pigs during in utero exposure to unscanned pulsed ultrasound at ISPTA 2.8 W/cm2. Mean temperature increases of 4.9 degrees C close to parietal bone and 1.2 degrees C in the midbrain were recorded after 2-min exposures. When exposures were repeated on the same sites in each fetus after death, the corresponding mean temperature increases were 4.9 degrees C and 1.3 degrees C, respectively. Cerebral blood perfusion had little cooling effect on ultrasound-induced heating in the guinea pig fetus of 57-61 days gestational age.
authors.affiliation: Department of Veterinary Clinical Sciences, University of Sydney, NSW Australia.
authors.forename: M M
authors.initials: MM
authors.lastname: Horder
authors.forename: S B
authors.initials: SB
authors.lastname: Barnett
authors.forename: G J
authors.initials: GJ
authors.lastname: Vella
authors.forename: M J
authors.initials: MJ
authors.lastname: Edwards
authors.forename: A K
authors.initials: AK
authors.lastname: Wood
mesh_terms: D000818:Animals; D001831:Body Temperature; D001921:Brain / Q000098:blood supply / Q000196:embryology*; D002560:Cerebrovascular Circulation; D005260:Female; D005865:Gestational Age; D006168:Guinea Pigs; D006358:Hot Temperature; D011247:Pregnancy; D012886:Skull / Q000196:embryology; D013997:Time Factors; D018617:Ultrasonography, Doppler, Pulsed / Q000009:adverse effects*; D016216:Ultrasonography, Prenatal / Q000009:adverse effects*