title: Blue rubber bleb nevus (Bean syndrome): evolution of four cases and clinical response to pharmacologic agents.
abstract: Blue rubber bleb nevus (BRBN) syndrome is a rare disorder characterized by distinctive cutaneous and gastrointestinal vascular malformations. The latter may lead to bleeding complications. We followed four affected children for at least 5 years. The evolution of their disease and the value of pharmacologic agents (steroids, interferon) in the management of some of these patients are discussed.
authors.affiliation: Department of Dermatology, Hospital del Niño Jesus, Tucumán, Argentina.
authors.forename: M D
authors.initials: MD
authors.lastname: Boente
authors.forename: M R
authors.initials: MR
authors.lastname: Cordisco
authors.forename: M D
authors.initials: MD
authors.lastname: Frontini
authors.forename: R A
authors.initials: RA
authors.lastname: Asial
mesh_terms: D001003:Anal Canal; D002648:Child; D002675:Child, Preschool; D005260:Female; D005528:Foot; D006471:Gastrointestinal Hemorrhage / Q000473:pathology*; D005770:Gastrointestinal Neoplasms / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D018329:Nevus, Blue / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*