Hydrogen tunneling in biology.
The mechanistic details of hydrogen transfer in biological systems are not fully understood. The traditional approach has been to use semiclassical transition-state theory. This theory cannot explain many experimental findings, however, so different approaches that emphasize the importance of quantum mechanics and dynamic effects should also be considered.
Kohen
A
A
Departments of Chemistry and Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA 94720, USA.
Klinman
J P
JP
D002384:Catalysis; D004798:Enzymes; D006859:Hydrogen; D007700:Kinetics; D008956:Models, Chemical; D014732:Vibration
D004798:Enzymes; D006859:Hydrogen