title: HSa of Staphylococcus aureus, a new member of the HU family of bacterial histone-like proteins.
abstract: Histone-like proteins of the HU family are small, sequence-independent DNA binding proteins that facilitate a variety of DNA transactions. Here we report isolation from cell-free extracts of Staphylococcus aureus of HSa, a new member of the HU family. The NH2-terminal amino acid sequence of HSa led to identification of the corresponding gene (hsa) using the genome sequence of S. aureus. HSa is 90 amino acids long (Mr = 9 620) and shares 64 to 80% identity with homologs found in the genus Bacillus.
authors.affiliation: Public Health Research Institute, New York, NY 10016, USA.
authors.forename: S
authors.initials: S
authors.lastname: Viter
authors.forename: K J
authors.initials: KJ
authors.lastname: Shaw
authors.forename: M L
authors.initials: ML
authors.lastname: Gennaro
mesh_terms: D000595:Amino Acid Sequence; D004268:DNA-Binding Proteins / Q000302:isolation & purification* / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D029968:Escherichia coli Proteins; D008969:Molecular Sequence Data; D008970:Molecular Weight; D013211:Staphylococcus aureus / Q000378:metabolism*
chemical_list: D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; C116822:hns protein, E coli