Low-frequency damped electroretinographic wavelets in young asymptomatic patients with dominant retinitis pigmentosa: a new electroretinographic finding.
OBJECTIVE
To describe a previously unreported electroretinographic (ERG) pattern in early retinitis pigmentosa (RP).


METHODS
Two case reports.


METHODS
Two unrelated young asymptomatic patients with autosomal-dominant retinitis pigmentosa were studied.


METHODS
Clinical findings and ERG responses were assessed.


RESULTS
No ERG responses were detected scotopically with low-luminance stimuli. With increasingly brighter stimuli, a series of three to five low-frequency damped wavelets developed under both scotopic and photopic conditions. The period of the wavelets was 25 to 37 msec.


CONCLUSIONS
Low-frequency damped ERG wavelets occur in some young asymptomatic patients with autosomal-dominant RP. The ERG pattern suggests that these wavelets are predominantly cone-generated.
Lam
B L
BL
Bascom Palmer Eye Institute, University of Miami School of Medicine, Florida, USA.
Liu
M
M
Hamasaki
D I
DI
D000328:Adult; D002648:Child; D003623:Dark Adaptation; D004596:Electroretinography; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D010375:Pedigree; D010775:Photic Stimulation; D020419:Photoreceptor Cells, Vertebrate / Q000502:physiology*; D012174:Retinitis Pigmentosa / Q000235:genetics / Q000503:physiopathology*; D014792:Visual Acuity; D014794:Visual Fields