Dietary n-3 polyunsaturated fatty acids and oxidants increase rat mammary tumor sensitivity to epirubicin without change in cardiac toxicity.
Germain
E
E
EA 2103, Université de François-Rabelais, Tours, France.
Lavandier
F
F
Chajès
V
V
Schubnel
V
V
Bonnet
P
P
Lhuillery
C
C
Bougnoux
P
P
D000818:Animals; D003683:Dehydroascorbic Acid / Q000494:pharmacology; D004042:Dietary Fats, Unsaturated / Q000494:pharmacology*; D015251:Epirubicin / Q000627:therapeutic use*; D015525:Fatty Acids, Omega-3 / Q000494:pharmacology*; D005260:Female; D015227:Lipid Peroxidation / Q000187:drug effects; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology; D008770:Methylnitrosourea; D016877:Oxidants / Q000494:pharmacology*; D051381:Rats; D014810:Vitamin E / Q000494:pharmacology*; D014812:Vitamin K / Q000494:pharmacology
D004042:Dietary Fats, Unsaturated; D015525:Fatty Acids, Omega-3; D016877:Oxidants; D014812:Vitamin K; D014810:Vitamin E; D015251:Epirubicin; D008770:Methylnitrosourea; D003683:Dehydroascorbic Acid