[Oligodendroglioma: a pathological and clinical study of 15 cases].
Oligodendrogliomas account for 4-5% of primary central nervous system tumours with a slow and infiltrative growth. We report the clinical and pathological findings of 15 cases of oligodendrogliomas. Eight patients were males and 7 were females. The ages ranged between 17 and 66 years, with a mean of 39.73 years. The symptoms reflected the growth and topography of the tumours; migraine (60%) and seizures (60%) were the most frequent symptoms. Frontal (n = 6), parietal (n = 2), temporal (n = 1) and occipital (n = 1) lobes were affected. Five patients undergone total resection of the tumor and 10 were submitted to partial resection, from which 3 received adjuvant radiotherapy, 1 adjuvant chemotherapy and 1 chemotherapy and radiotherapy. The overall recurrence rate was 60% for a 32 month follow up. Five recurrences were observed in patients submitted only to the surgical treatment and 4 in which adjuvant radio or chemotherapy were performed. These results are similar with the literature and may contribute to further understanding the biological behavior of these rare tumours.
Serviço de Anatomia Patológica (SAP), Hospital de Clínicas (HC), Universidade Federal do Paraná (UFPR), Curitiba, PR, Brasil. jsreis@hotmail.com ou neuropat@hc.ufpr.br
J S
JS
Reis Filho
M R
MR
Netto
B G
BG
Sluminsky
L A
LA
Dellé
A
A
Antoniuk
R
R
Ramina
L F
LF
Torres
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D001932:Brain Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D001938:Brazil / Q000453:epidemiology; D016543:Central Nervous System Neoplasms / Q000453:epidemiology / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009837:Oligodendroglioma / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy
Oligodendrogliomas. Estudo anatomopatológico e clínico de 15 casos.