Accelerated phase of Chédiak-Higashi syndrome diffuse white-matter-enhancing lesions.
We present the CT and MRI findings of a patient with Chédiak-Higashi syndrome in the accelerated phase with marked white-matter abnormalities. Pathologic and clinical features allow diagnosis of this condition, which in this case had dramatic neuroradiographic manifestations not well described in previous reports.
Mallinckrodt Institute of Radiology, St. Louis Children's Hospital, Department of Radiology, 510 South Kingshighway Boulevard, St. Louis, MO 63110, USA.
T E
TE
Herman
B C
BC
Lee
D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology*; D002609:Chediak-Higashi Syndrome / Q000000981:diagnostic imaging* / Q000473:pathology*; D002675:Child, Preschool; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed