[The neuronal reactions of the cat motor cortex to electrical stimulation of the ventral tegmental area as a conditioned signal for the reflex of placing the forelimb on a support].
Electrical stimulation (50-100 pulses, 100-500 Hz) of the ventral tegmental area (VTA) in the vicinity of the n. interpeduncularis in the frontal plane AP2-AP4, L1-L2 caused a cat to grab food placed near its mouth. The conditioned forepaw placing reaction was elaborated using food reinforcement and VTA stimulation as a conditioned stimulus. The conditioned reflex, being once established, was repeatedly performed without extinction in the course of up to 250 trials without food reinforcement. Short (5-10 pulses) conditioned VTA stimulation evoked a prolonged (up to 1000 ms or longer) activation of neurons of the motor cortex and caused a substitution of the inhibitory phase of response to stimulation of the parietal cortex in poststimulus interval in 50-200 ms for the late secondary excitatory response.
Department of Higher Nervous Activity, Lomonosov State University, Moscow.
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Maĭorov
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Khludova
D000818:Animals; D002415:Cats; D003214:Conditioning, Classical / Q000502:physiology*; D004558:Electric Stimulation; D005552:Forelimb / Q000502:physiology*; D008839:Microelectrodes; D009044:Motor Cortex / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D010296:Parietal Lobe / Q000502:physiology; D013997:Time Factors; D017557:Ventral Tegmental Area / Q000502:physiology*; D014851:Wakefulness / Q000502:physiology
Reaktsii neĭronov motornoĭ kory koshki na élektricheskoe razdrazhenie ventral'noĭ chasti pokryshki srednego mozga v kachestve uslovnogo signala dlia refleksa postanovki peredneĭ konechnosti na oporu.