Isolation of respiratory bacterial pathogens from the throats of healthy infants fed by different methods.
Most bacterial infections are caused by organisms that have already colonized the host. Bacterial attachment to pharyngeal cells and proliferation may be necessary to infect the lower respiratory tract or middle ear. We investigated the incidence of pathogenic bacteria isolated from the throat of healthy infants with different feeding methods. The protecting role of breastmilk is also discussed. The incidence of respiratory bacterial pathogens isolated from the oropharynx of 113 normal infants with different feeding methods was investigated. Group A beta haemolytic Streptococcus, Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis were selected as respiratory bacterial pathogens. No respiratory bacterial pathogens were detected in breastfed and mixed-fed infants. Haemophilus influenzae and Moraxella catarrhalis were isolated from the oropharynx of formula-fed infants. The incidence of respiratory bacterial pathogens did differ among infants with different feeding methods. These results suggest that breastmilk may inhibit the colonization by respiratory bacterial pathogens of the throat of infants, by enhancing mucosal immunity against respiratory tract infection.
Hokama
T
T
Maternal and Child Health Department, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.
Yara
A
A
Hirayama
K
K
Takamine
F
F
D001419:Bacteria / Q000302:isolation & purification* / Q000472:pathogenicity; D001424:Bacterial Infections / Q000382:microbiology; D001903:Bottle Feeding / Q000009:adverse effects; D001942:Breast Feeding; D006801:Humans; D018928:Immunity, Mucosal / Q000276:immunology; D015994:Incidence; D007223:Infant; D010614:Pharynx / Q000382:microbiology*; D015995:Prevalence; D012141:Respiratory Tract Infections / Q000382:microbiology