A case of Down's syndrome associated with progressive extradural neuroblastoma.
We describe a case of Down's syndrome associated with progressive extradural neuroblastoma. Postmortem aspiration of the bone marrow revealed diffuse infiltration by tumor cells, in which trisomy 21 was found by fluorescence in hybridization in situ.
Koyama
T
T
Department of Pediatrics, National Okayama Hospital, 2-13-1 Minamigata, Okayama-City, 700-8566, Japan.
Kanadani
T
T
Tanaka
M
M
Nakahara
S
S
Yamadori
I
I
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001856:Bone Marrow Examination; D002648:Child; D004314:Down Syndrome / Q000150:complications* / Q000175:diagnosis; D015174:Epidural Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007796:Laminectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D009447:Neuroblastoma / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D011379:Prognosis; D018714:Radiotherapy, Adjuvant