Peripheral nerve sheath tumor of the diaphragm with osseous differentiation in a one-year-old dog.
A 12-month-old, spayed female German shepherd dog was referred to the Veterinary Teaching Hospital for repair of a diaphragmatic hernia. Abdominal exploration revealed an intact diaphragm, but thoracic exploration revealed a large mass originating from the diaphragm. Resection of the mass was incomplete and required reconstruction of the diaphragm. On histopathology, the mass was composed mainly of spindle-shaped cells with occasional areas of osseous and chondroid tissue. The tumor was diagnosed as a peripheral nerve sheath tumor (PNST) with chondro-osseous differentiation. The dog was released four days after surgery; however, she began having difficulty breathing seven days after discharge, and the owners elected euthanasia. A necropsy was not performed. This is the first known report of a PNST originating in the diaphragm of a dog.
Anderson
G M
GM
Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Canada.
Dallaire
A
A
Miller
L M
LM
Miller
C W
CW
D000818:Animals; D003964:Diaphragm; D004283:Dog Diseases / Q000473:pathology / Q000601:surgery*; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D009455:Neurofibroma / Q000601:surgery / Q000662:veterinary*; D010524:Peripheral Nervous System Neoplasms / Q000601:surgery / Q000662:veterinary*