Symptomatic moyamoya disease and aortic coarctation in a patient with Noonan's syndrome: strategies for management.
Noonan's syndrome is a multiple congenital anomaly syndrome with characteristic facial features, short stature, congenital heart defects and a recently reported association with moyamoya disease. We report a case of symptomatic moyamoya disease and aortic coarctation in a patient with Noonan's syndrome. The case illustrates the need for a rational, coordinated treatment plan for dealing with the cardiac and neurologic syndromic anomalies to help avoid undesirable outcomes.
Schuster
J M
JM
Department of Neurological Surgery, University of Washington, Seattle, Wash., USA. jschu@u.washington.edu
Roberts
T S
TS
D001017:Aortic Coarctation / Q000209:etiology* / Q000628:therapy; D002560:Cerebrovascular Circulation; D002648:Child; D005260:Female; D006801:Humans; D009072:Moyamoya Disease / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D009634:Noonan Syndrome / Q000150:complications*; D011859:Radiography