Incidence of and preoperative predictors for delirium after cardiac surgery.
Incidence of and preoperative predictors for postoperative delirium were studied in 296 patients (age 26-83 years, mean age 63 years) undergoing elective cardiac surgery. Delirium occurred in 40 (13.5%) patients. Predictors included old age, low level of albumin, poor physical condition, use of nifedipine, and a high ratio of the amino acids phenylalanine to the sum of isoleucine, leucine, valine, tyrosine, and tryptophan. These findings suggest that preoperative physical condition and amino acid disturbances may be related to delirium after cardiac surgery in the elderly.
Psychiatric Hospital Amsterdam, The Netherlands. ts_psych@wxs.nl
R C
RC
van der Mast
W W
WW
van den Broek
D
D
Fekkes
L
L
Pepplinkhuizen
J D
JD
Habbema
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000596:Amino Acids / Q000097:blood; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D003693:Delirium / Q000097:blood / Q000209:etiology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D016017:Odds Ratio; D011237:Predictive Value of Tests; D012372:ROC Curve; D012709:Serum Albumin / Q000378:metabolism; D013963:Thyroid Hormones / Q000097:blood; D014803:Vitamin B Complex / Q000097:blood
D000596:Amino Acids; D012709:Serum Albumin; D013963:Thyroid Hormones; D014803:Vitamin B Complex; D006854:Hydrocortisone