Six-year prospective study of risk and prognostic factors in patients with nosocomial sepsis caused by Acinetobacter baumannii.
In this prospective study, the risk factors associated with nosocomial sepsis Caused by Acinetobacter baumannii or Pseudomonas aeruginosa were compared. Prior use of broad-spectrum antibiotics, urinary tract catheter, prior surgery, and mechanical ventilation were significantly associated with nosocomial sepsis caused by Acinetobacter baumannii. The mean prognostic factors significantly associated with mortality were known focus of infection, multiresistant Acinetobacter baumannii, and inappropriate antibiotic treatment. Adequate knowledge of these findings is important to ensure appropriate management of patients and rational use of antibiotics.
Unidad de Enfermedades Infecciosas, Servicio de Medicina Interna, Hospital Universitario Virgen de la Arrixaca, El Palmar, Murcia, Spain.
J
J
Gómez
E
E
Simarro
V
V
Baños
L
L
Requena
J
J
Ruiz
F
F
García
M
M
Canteras
M
M
Valdés
D000150:Acinetobacter / Q000187:drug effects; D000151:Acinetobacter Infections / Q000209:etiology* / Q000401:mortality; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000494:pharmacology; D003428:Cross Infection / Q000382:microbiology* / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D011552:Pseudomonas Infections / Q000209:etiology / Q000401:mortality; D012121:Respiration, Artificial / Q000009:adverse effects; D012307:Risk Factors; D014546:Urinary Catheterization / Q000009:adverse effects
D000900:Anti-Bacterial Agents