Bioactive glasses induce chemiluminescence by human polymorphonuclear leukocytes.
The effect of bioactive glasses on human polymorphonuclear leukocytes (PMNLs) were studied in vitro by a chemiluminescence (CL) assay. Eight different glasses were chosen. All glasses induced a rapid CL response by human PMNLs, which proved to be dose dependent. The CL response also seemed to depend on the durability of the glasses. The least durable glass caused the highest CL response, and highly durable glasses caused only low CL responses by the cells.
Institute of Occupational Health, Helsinki, Finland.
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Lindfors
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Klockars
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Ylänen
D018786:Bone Substitutes / Q000633:toxicity*; D005898:Glass; D006801:Humans; D066298:In Vitro Techniques; D008163:Luminescent Measurements; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D009504:Neutrophils / Q000187:drug effects* / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism; D012822:Silicon Dioxide / Q000633:toxicity
D018786:Bone Substitutes; D017382:Reactive Oxygen Species; D012822:Silicon Dioxide