Interventional radiology in the treatment of renal artery stenosis.
Percutaneous transluminal renal angioplasty (PTRA) alone or in combination with stent implantation, is increasingly used as an alternative technique to surgical revascularization for treatment of renal artery stenosis (RAS) wich may cause hypertension or jeopardize renal function. Herein we report the results obtained with 305 PTRAs performed in 242 hypertensive patients, 144 of whom had atherosclerotic RAS, 69 fibromuscolar dysplasia, 15 Ras in transplanted kidneys, 6 restenosis in surgically revascularized kidneys, 4 Takayasu arteritis and 4 neurofibromatosis. Stents were implanted in 68 cases, mostly in atherosclerotic stenoses. The technical success was achieved in 261 arteries (85.6%), with 33 failures (10.8%) and 11 (3.6%) procedures not completed for anatomical reasons. PTRA related complications were observed in 23 cases (7.5%), but no fatalities occurred. An overall benefit on blood pressure control was observed in 41% of patients with atherosclerotic RAS and in 68% of those with fibromuscolar dysplasia. It appears that independently from the ethiology PTRA is technically effective in correcting RAS; yet the position of PTRA with respect to that of medical or surgical treatment needs to be better delineated through randomized, controlled studies aimed at comparing the clinical efficacies of these different approaches.
Department of Radiology, I.R.C.C.S. Ospedale Maggiore Policlinico, Milano, Italy.
A
A
Lovaria
A
A
Nicolini
D
D
Meregaglia
S
S
Saccheri
R
R
Rivolta
E
E
Montanari
A
A
Morganti
P
P
Rossi
D000328:Adult; D000368:Aged; D000800:Angioplasty, Balloon / Q000379:methods*; D001161:Arteriosclerosis / Q000628:therapy; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000628:therapy; D007668:Kidney / Q000098:blood supply / Q000000981:diagnostic imaging; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional / Q000379:methods*; D012039:Regional Blood Flow; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging / Q000628:therapy*; D015607:Stents; D016896:Treatment Outcome