Guiaflavine, a new bisindole quaternary alkaloid from the stem bark of Strychnos guianensis.
A reinvestigation of Strychnos guianensis resulted in the isolation of a colored quaternary bisindole alkaloid from the stem bark. The structure of this new substance, guiaflavine (1), was defined by detailed spectroscopic methods and comparison with model compounds.
Laboratory of Pharmacognosy, Institute of Pharmacy, University of Liège, CHU, Tour 4, Avenue de l'Hôpital 1, B-4000 Liège 1, Belgium.
J
J
Penelle
M
M
Tits
P
P
Christen
V
V
Brandt
M
M
Frédérich
L
L
Angenot
D000818:Animals; D002855:Chromatography, Thin Layer; D007211:Indoles; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000737:chemistry; D011807:Quinolizines / Q000302:isolation & purification* / Q000633:toxicity; D013020:South America; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013331:Strychnine / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000633:toxicity; D014197:Trees
D007211:Indoles; D010936:Plant Extracts; D011807:Quinolizines; C120733:guiaflavine; D013331:Strychnine