Autoimmunity: Another pathway towards arthritis.
A new pathway leading to arthritis has been revealed by the discovery that antibodies specific for a ubiquitously expressed antigen are able to transfer a severe arthritic phenotype in mice. This new model will be useful for further analyses of the different pathways involved in rheumatoid arthritis.
Holmdahl
R
R
Lund University, Section for Medical Inflammation Research, Sölvegatan 19, 22362, Lund, Sweden. Rikard.Holmdahl@inflam.lu.se
D000818:Animals; D001168:Arthritis / Q000209:etiology* / Q000235:genetics / Q000276:immunology*; D015551:Autoimmunity; D004195:Disease Models, Animal; D005802:Genes, MHC Class II / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D051379:Mice; D008822:Mice, Transgenic; D010641:Phenotype
D007074:Immunoglobulin G