Detection of suction and regurgitation of the implantable centrifugal pump based on the motor current waveform analysis and its application to optimization of pump flow.
In this study, a detection algorithm for suction and regurgitation of the centrifugal pump during left heart bypass without relying on external flow or pressure sensors was developed and evaluated in acute studies using adult goats. The detection scheme relies on power spectral density (PSD) analysis of the motor current waveform through which the waveform deformation index (WDI) is obtained. This index is defined as the ratio of the fundamental component of the PSD to the higher PSD components, and its value increases with the deformation of the basic waveform. By assuming that the undistorted motor current waveform can be represented by a pure sine waveform, we theoretically synthesized various waveforms which have different second harmonic components. We were able to synthesize the waveform whose shape was close to the distorted motor current waveform under varying suction levels obtained in a mock loop study. From this study, we came to the conclusion that the WDI value of 0.2 can serve as a threshold level in deciding the suction and regurgitation speeds (rpm) during left heart bypass. In the study using adult goats, we were successful in minimizing both regurgitation and suction when the centrifugal pump speed was adjusted based on the WDI algorithm. The resultant bypass flow ranged from 1.5 to 2.0 L/min which was around 60% of the total flow. Further study is underway to evaluate the applicability of the WDI method in optimizing bypass pump flow.
Yuhki
A
A
Biomedical Systems Engineering, Yamagata University, Japan.
Hatoh
E
E
Nogawa
M
M
Miura
M
M
Shimazaki
Y
Y
Takatani
S
S
D000465:Algorithms; D000818:Animals; D001011:Aorta / Q000502:physiology; D016279:Atrial Function, Left / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D003198:Computer Simulation; D011211:Electric Power Supplies; D004867:Equipment Design; D004868:Equipment Failure; D005583:Fourier Analysis; D006041:Goats; D018611:Heart Bypass, Left / Q000295:instrumentation*; D006353:Heart-Assist Devices; D018056:Hemorheology; D008955:Models, Cardiovascular; D011673:Pulsatile Flow / Q000502:physiology; D012815:Signal Processing, Computer-Assisted