Heterophile antibodies to bovine and caprine proteins causing false-positive human immunodeficiency virus type 1 and other enzyme-linked immunosorbent assay results.
Heterophile antibodies are a well-recognized cause of erroneous results in immunoassays. We describe here a 22-month-old child with heterophile antibodies reactive with bovine serum albumin and caprine proteins causing false-positive results to human immunodeficiency virus type 1 and other infectious serology testing.
Division of Clinical Pathology, Department of Pathology, University of Utah, ARUP Laboratories and the ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84132, USA.
J H
JH
Willman
T B
TB
Martins
T D
TD
Jaskowski
H R
HR
Hill
C M
CM
Litwin
D000818:Animals; D000910:Antibodies, Heterophile / Q000032:analysis* / Q000276:immunology; D000956:Antigens, Viral / Q000032:analysis / Q000276:immunology; D002417:Cattle; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D006041:Goats / Q000097:blood* / Q000276:immunology; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D007223:Infant; D008297:Male; D008894:Milk Proteins / Q000276:immunology; D012709:Serum Albumin / Q000276:immunology*
D000910:Antibodies, Heterophile; D000956:Antigens, Viral; D008894:Milk Proteins; D012709:Serum Albumin