[Effect of Arnica montana tincture on some hydrolytic enzyme activities of rat liver in experimental toxic hepatitis].
Effects of tinctura arnica on arginase, adenosine triphosphatase, glucose-6-phosphatase and 5'-nucleotidase activities of rats liver in case of experimental toxic hepatitis have been studied. Toxic hepatitis was caused by 2 times interstomach administration of 0.25 ml oil solution of carbon tetrachloride per 100 g of animal weight. 20 mkl/100 g of tinctura arnica was administered every day per os for 14 days. The enzyme activities have been investigated at 3, 7 and 17 days. A significant demention of a studied hydrolytic enzyme activities in rats liver at intoxication of the body by CCI4 has been shown. It has been established that tinctura arnica administered per os to intoxicated animals sped up the normalization of hydrolytic enzyme activities in rat liver.
Bucovinien State Medical Academy, Chernivtsi, Ukraine.
I M
IM
Iaremiĭ
I F
IF
Meshchyshen
N P
NP
Hrihor'ieva
L S
LS
Kostiuk
D015720:5'-Nucleotidase / Q000378:metabolism; D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D001119:Arginase / Q000378:metabolism; D002252:Carbon Tetrachloride Poisoning / Q000201:enzymology; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology*; D005952:Glucose-6-Phosphatase / Q000378:metabolism; D006868:Hydrolysis; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats
D010936:Plant Extracts; D015720:5'-Nucleotidase; D005952:Glucose-6-Phosphatase; D001119:Arginase; D000251:Adenosine Triphosphatases
Vplyv nastoĭki arniky hirs'koï na aktyvnist' deiakykh hidrolitychnykh fermentiv pechinky shchuriv za umov eksperymental'noho toksychnoho hepatytu.