Developmental components of resting ventilation among high- and low-altitude Andean children and adults.
This paper evaluates the age-associated changes of resting ventilation of 115 high- and low-altitude Aymara subjects, of whom 61 were from the rural Aymara village of Ventilla situated at an average altitude of 4,200 m and 54 from the rural village of Caranavi situated at an average altitude of 900 m. Comparison of the age patterns of resting ventilation suggests the following conclusions: 1) the resting ventilation (ml/kg/min) of high-altitude natives is markedly higher than that of low-altitude natives; 2) the age decline of ventilation is similar in both lowlanders and highlanders, but the starting point and therefore the age decline are much higher at high altitude; 3) the resting ventilation that characterizes high-altitude Andean natives is developmentally expressed in the same manner as it is at low altitude; and 4) the resting ventilation (ml/kg/min) of Aymara high-altitude natives is between 40-80% lower than that of Tibetans.
Frisancho
A R
AR
University of Michigan, Ann Arbor 48109, USA. arfrisan@umich.edu
Juliao
P C
PC
Barcelona
V
V
Kudyba
C E
CE
Amayo
G
G
Davenport
G
G
Knowles
A
A
Sanchez
D
D
Villena
M
M
Vargas
E
E
Soria
R
R
D000222:Adaptation, Physiological; D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology*; D000531:Altitude; D001784:Blood Gas Analysis; D001838:Bolivia; D002648:Child; D006801:Humans; D012123:Pulmonary Ventilation; D014797:Vital Capacity