Antioxidant enzyme activities and lipid peroxides in the plasma of patients with benign prostatic hyperplasia or prostate cancer are not predictive.
In this study, lipid peroxide and total sulfhydryl contents and activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) were investigated in the plasma of patients with benign prostatic hyperplasia (BPH) and prostate cancer. No significant change was found in lipid peroxidation or antioxidant systems in the plasma of patients with BPH and prostate cancer. The results indicate that evaluation of the prooxidant-antioxidant balance in the plasma of BPH and prostate cancer patients cannot be used as a marker to discriminate between these diseases.
Department of Biochemistry, Istanbul Faculty of Medicine, University of Istanbul, Capa, Turkey.
S
S
Doğru-Abbasoğlu
G
G
Aykaç-Toker
T
T
Koçak
E
E
Unlüer
M
M
Uysal
D000368:Aged; D000369:Aged, 80 and over; D002374:Catalase / Q000097:blood*; D003937:Diagnosis, Differential; D005979:Glutathione Peroxidase / Q000097:blood*; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011470:Prostatic Hyperplasia / Q000097:blood* / Q000175:diagnosis* / Q000201:enzymology; D011471:Prostatic Neoplasms / Q000097:blood* / Q000175:diagnosis* / Q000201:enzymology; D013482:Superoxide Dismutase / Q000097:blood*
D008054:Lipid Peroxides; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase