[Detection of antibacterial activity in the urine of children: a comparison of three tests].
BACKGROUND
Detection of antibacterial activity in urine is important for the diagnosis of urinary tract infections and for assessment of patient compliance with antibiotic therapy.


METHODS
Urines of paediatric inpatients were examined by the Bacillus subtilis agar diffusion test and two commercial test strips (Micur BT and Urotest AB).


RESULTS
566 urines of 431 patients were examined. The B. subtilis agar diffusion test was the most reliable method (accuracy 98.8%). Micur BT showed a comparatively low specificity (87.6%) and Urotest AB had a comparatively low sensitivity (86.0%).


CONCLUSIONS
The B. subtilis agar diffusion test is the most reliable method for detection of antibacterial activity in the urine of children.
Universitäts-Kinderklinik, Tübingen.
J E
JE
Hoppe
M
M
Schlegel
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D015169:Colony Count, Microbial; D016903:Drug Monitoring / Q000379:methods*; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010349:Patient Compliance; D012680:Sensitivity and Specificity; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000652:urine*
D000900:Anti-Bacterial Agents
Nachweis antibakterieller Hemmstoffe im Urin von Kindern: Vergleich dreier Teste.