Flavonols and flavones of parsley cell suspension culture change the antioxidative capacity of plasma in rats.
The flavonoid aglycones from an illuminated parsley (Petroselinum crispum (Mill.) Nym.) cell suspension culture were identified and quantified as the flavones apigenin, luteolin and chrysoeriol and the flavonols kaempferol, quercetin and isorhamnetin. Flavonoid extracts from these cultures were purified by solid phase extraction from RP C-18 phase and given by gavage to rats. Only extract from illuminated culture increased the antioxidative capacity (AOC) of blood plasma temporarily with maximum values after 1 h. It is concluded that the course of AOC reflects changes in the plasma content of flavonoids.
Hempel
J
J
Deutsches Institut für Ernährungsforschung, Abteilung Präventiv-medizinische Lebensmittelforschung, Bergholz-Rehbrücke, Germany.
Pforte
H
H
Raab
B
B
Engst
W
W
Böhm
H
H
Jacobasch
G
G
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D019661:Apiaceae / Q000737:chemistry*; D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology*; D006027:Glycosides / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D013058:Mass Spectrometry; D051381:Rats; D017208:Rats, Wistar
D000975:Antioxidants; D005419:Flavonoids; D006027:Glycosides