Lack of osmosensitive CD9 expression in rat liver cells.
CD9 mRNA was found to be strongly expressed in H4IIE rat hepatoma cells and rat liver macrophages (Kupffer cells), whereas the expression was weak in primary rat liver parenchymal cells. An osmosensitive regulation of CD9 mRNA levels was not detectable in all three cell types, whereas this has recently been described for Madin Darby canine kidney cells and rabbit renal papillary cells (see text). The findings suggest that osmoregulation of specific genes may exhibit cell type specificity.
Medizinische Universitätsklinik der Heinrich-Heine-Universität Düsseldorf, Klinik für Gastroenterologie, Hepatologie und Infektiologie, Düsseldorf, Deutschland.
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Warskulat
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Hammermann
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Häussinger
D000818:Animals; D015703:Antigens, CD / Q000032:analysis / Q000235:genetics*; D002460:Cell Line; D003001:Cloning, Molecular; D004285:Dogs; D005910:Glioma; D007728:Kupffer Cells / Q000166:cytology / Q000502:physiology*; D007739:L Cells; D008099:Liver / Q000166:cytology / Q000502:physiology*; D008114:Liver Neoplasms, Experimental; D008297:Male; D008562:Membrane Glycoproteins / Q000235:genetics; D051379:Mice; D009994:Osmolar Concentration; D012333:RNA, Messenger / Q000235:genetics; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D060245:Tetraspanin 29; D014158:Transcription, Genetic; D014407:Tumor Cells, Cultured
D015703:Antigens, CD; C554870:Cd9 protein, mouse; D008562:Membrane Glycoproteins; D012333:RNA, Messenger; D060245:Tetraspanin 29