Pentamidine is a potent inhibitor of [3H]idazoxan binding to imidazoline I2 receptors.
Department of Pathology, University of North Carolina, Chapel Hill 27599, USA.
D H
DH
Wood
J E
JE
Hall
B G
BG
Rose
D W
DW
Boykin
R R
RR
Tidwell
D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology; D001665:Binding Sites; D001667:Binding, Competitive; D002462:Cell Membrane / Q000378:metabolism; D003458:Cryptosporidium / Q000187:drug effects; D019329:Idazoxan / Q000493:pharmacokinetics*; D054755:Imidazoline Receptors; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D010419:Pentamidine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology*; D011010:Pneumocystis / Q000187:drug effects; D011869:Radioligand Assay; D051381:Rats; D011955:Receptors, Drug / Q000037:antagonists & inhibitors / Q000378:metabolism*
D000890:Anti-Infective Agents; D054755:Imidazoline Receptors; D011955:Receptors, Drug; D010419:Pentamidine; D019329:Idazoxan