Neuropsychological deficits in withdrawn cocaine-dependent males.
Previous research suggests that cocaine abuse may result in neuropsychological deficits. To examine this further, we compared cocaine-withdrawn patients (N = 35) to normal controls (N = 17) on tasks of attention, concentration, perceptual-motor speed, and cognitive flexibility. The withdrawn cocaine patients performed significantly worse on Arithmetic, Grooved Peg Board Dominant and Non-Dominant, and Trails B tests. These findings suggest that withdrawn cocaine-dependent patients have more neuropsychological impairment than normal controls.
Smelson
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DA
New Jersey Veterans Administration Medical Center, Robert Wood Johnson Medical School Department of Psychiatry, USA.
Roy
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A
Santana
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S
Engelhart
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C
D000328:Adult; D019970:Cocaine-Related Disorders / Q000523:psychology* / Q000534:rehabilitation; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D012720:Severity of Illness Index; D013375:Substance Withdrawal Syndrome / Q000150:complications* / Q000523:psychology*