Hormone replacement therapy.
Hormone replacement therapy is increasingly being used for purposes unrelated to the alleviation of menopausal symptoms, such as the prevention of osteoporosis and cardiovascular disease. Clinical trials, however, suggest that the one drug/many purposes concept may be too optimistic. The availability of new estrogen-like compounds and the discovery of a second estrogen receptor have opened new possibilities for more specific drug development.
Gaubius Laboratory TNO-PG 2215, 2301 CE, Leiden, The Netherlands. t.kooistra@pg.tno.nl
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D000818:Animals; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D011960:Receptors, Estrogen / Q000187:drug effects / Q000502:physiology
D011960:Receptors, Estrogen