Antinociceptive, anti-inflammatory and antipyretic effects of ethanol extract of Clerodendron serratum roots in experimental animals.
The alcoholic extract (50, 100 and 200 mg/kg, p.o) of Clerodendron serratum roots produced a significant antinociceptive, anti-inflammatory and antipyretic activities in animal models. The results support the traditional claims of C. serratum as a remedy for pain, inflammation and fever.
Medicinal Chemistry Research Centre, Institute of Pharmacology, Chennai Medical College, India.
N
N
Narayanan
P
P
Thirugnanasambantham
S
S
Viswanathan
V
V
Vijayasekaran
E
E
Sukumar
D000700:Analgesics / Q000009:adverse effects / Q000494:pharmacology*; D018712:Analgesics, Non-Narcotic / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000009:adverse effects / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar
D000700:Analgesics; D018712:Analgesics, Non-Narcotic; D000894:Anti-Inflammatory Agents, Non-Steroidal; D010936:Plant Extracts