MRI measurement of the functional blood flow changes in a large superficial vein draining the motor cortex.
In this study, phase-contrast MR techniques are applied in order to measure the blood flow changes induced by a motor task in a large superficial vein draining the motor cortex. The measurements were applied to six healthy volunteers, in motor rest conditions and during performance of a motor task. The latter consisted of sequential finger-to-thumb opposition. The task was actually executed and mentally simulated. Significant blood flow increases were found when changing from from mental simulation to actual execution of the motor task (increases ranging between 1.6 and 10.3 ml/min, i.e. 9% and 45%, respectively) and from resting conditions to actual execution of the motor task (increases ranging between 1.7 and 14.0 ml/min, i.e. 32% and 72%, respectively).
INSERM U438, Université Joseph Fourier, LRC CEA Hôpital Michallon, Grenoble, France. Chantal.Delon@inserm-u438.uif-grenoble.fr
C
C
Delon-Martin
M
M
Roth
S
S
Morand
R
R
Massarelli
V
V
Belle
J
J
Decety
J
J
Felblinger
M
M
Décorps
C
C
Segebarth
D000328:Adult; D001783:Blood Flow Velocity; D002550:Cerebral Veins / Q000502:physiology; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009044:Motor Cortex / Q000098:blood supply*; D015203:Reproducibility of Results