The treatment of malignancy by hyperthermia.
The use of hyperthermia for the selective destruction of tumours may be applied by a whole body, surgical perfusion or interstitial techniques. The main determinant of selectivity is tumour blood flow. The effects of hyperthermia may be augmented by step-down heating, manipulating pH changes and sensitisation by chemotherapy or specific pharmacological agents.
Monash University Department of Surgery, Alfred Hospital, Prahran, Victoria, Australia. chris.christophi@med.monash.edu.au
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D010478:Chemotherapy, Cancer, Regional Perfusion; D003131:Combined Modality Therapy; D006358:Hot Temperature; D006801:Humans; D006979:Hyperthermia, Induced / Q000191:economics / Q000379:methods*; D008872:Microwaves; D009369:Neoplasms / Q000098:blood supply / Q000473:pathology / Q000628:therapy*; D014465:Ultrasonics