A case of cutaneous extramedullary hematopoiesis in myelofibrosis with a preponderance of eosinophilic precursor cells.
A 48-year-old Korean man with myelofibrosis had erythematous papules and nodules on his scalp, anterior chest, back, lower abdomen, and both thighs. Skin biopsy showed cellular infiltration on the perivascular dermis and subcutaneous fat. Infiltrates were composed mainly of myeloid cells, especially of eosinophilic precursor cells. Erythroid and a few megakaryocytic precursors were also found. We diagnosed cutaneous extramedullary hematopoiesis with an interesting preponderance of eosinophilic precursor cells.
Kwon
K S
KS
Department of Dermatology, Pusan National University College of Medicine, Korea.
Lee
J B
JB
Jang
H S
HS
Chung
T A
TA
Oh
C K
CK
D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D004803:Eosinophilic Granuloma / Q000175:diagnosis / Q000473:pathology*; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000175:diagnosis / Q000473:pathology*; D012867:Skin / Q000473:pathology*