Role of allergy in nasal polyps of Thai patients.
As distinct from many countries, allergy in Thailand is of the perennial type which may play a role in the formation of nasal polyps. Forty consecutive patients with nasal polyps and 30 normal subjects as control were studied at the Allergy Clinic, Department of Otolaryngology, Pramongkutklao Hospital. A positive clinical history and skin allergy testing are diagnostic criteria for allergy. In the nasal polyps group, these were 28 males and 12 females, aged between 12-65 years, with an average age of 38.5 years. In the control group, there were 18 males and 12 females, aged between 15-53 yeas, with an average age of 34 years. All had received prick skin testing with 6 common aeroallergens. The prick skin test was considered positive when the wheal was > or = 3 mm with surrounding erythema. Twenty-four of 40 patients (60%) with nasal polyps had a positive prick skin test, while 6 in the 30 control cases (20%) had a positive prick skin test. This difference was statistically significant (P = 0.0019), Odd's ratio = 6.0 which means allergic persons were 6 times more prone to have polyps form than normal persons.
Pramongkutklao College of Medicine, Bangkok, Thailand.
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Pumhirun
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Limitlaohapanth
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Wasuwat
D000293:Adolescent; D000328:Adult; D000368:Aged; D000485:Allergens / Q000009:adverse effects; D000818:Animals; D039741:Antigens, Dermatophagoides; D002648:Child; D003058:Cockroaches / Q000276:immunology; D004391:Dust / Q000009:adverse effects; D005260:Female; D006023:Glycoproteins / Q000009:adverse effects; D006801:Humans; D006967:Hypersensitivity / Q000150:complications* / Q000276:immunology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000453:epidemiology / Q000209:etiology*; D012882:Skin Tests; D011795:Surveys and Questionnaires; D013785:Thailand / Q000453:epidemiology
D000485:Allergens; D039741:Antigens, Dermatophagoides; D004391:Dust; D006023:Glycoproteins