Ergotamine-induced intermittent claudication.
We report about a female patient with intermittent claudication caused by ergotamine. She used ergotamine as a treatment for migraine headaches for more than 4 years. The claudication began 7 month before admission. Colour Doppler sonography and angiography showed severe stenosis of the left external iliac and superficial femoral artery. The patient was treated with phenprocoumon for one year after withdrawal of ergotamine. After that the superficial femoral stenosis disappeared completely, but the external iliac stenosis was still present and was consequently successfully treated by atherectomy. The histology showed a fibrosis of the intima and a hypertrophy of the media.
Department for Angiology, University of Essen, Germany.
S
S
Bräunlich
K
K
Kröger
K
K
Massalha
G
G
Rudofsky
D000328:Adult; D000792:Angiography; D004878:Ergotamine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007383:Intermittent Claudication / Q000139:chemically induced* / Q000175:diagnosis; D007511:Ischemia / Q000139:chemically induced / Q000175:diagnosis; D007866:Leg / Q000098:blood supply; D008881:Migraine Disorders / Q000188:drug therapy*; D018615:Ultrasonography, Doppler, Color
D004878:Ergotamine