Accelerated phase of Chédiak-Higashi syndrome diffuse white-matter-enhancing lesions.
We present the CT and MRI findings of a patient with Chédiak-Higashi syndrome in the accelerated phase with marked white-matter abnormalities. Pathologic and clinical features allow diagnosis of this condition, which in this case had dramatic neuroradiographic manifestations not well described in previous reports.
Herman
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TE
Mallinckrodt Institute of Radiology, St. Louis Children's Hospital, Department of Radiology, 510 South Kingshighway Boulevard, St. Louis, MO 63110, USA.
Lee
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BC
D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology*; D002609:Chediak-Higashi Syndrome / Q000000981:diagnostic imaging* / Q000473:pathology*; D002675:Child, Preschool; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed