[The effect of an antioxidant preparation based on bioflavonoids and vitamin C on the antioxidant activity of blood plasma].
The effect of single and long-term reception of the antioxidant preparation Magnum C (MC) on blood plasma antioxidant activity (AOA) of volunteers has been investigated. AOA was measured with chemiluminescence test using the hemoglobin-hydrogen peroxide-luminol system. MC contains ethereal form of vitamin C and bioflavonoids as the basic antioxidant components. It was determined that blood plasma AOA was increased on the average by 36% (p < 0.01) 3 hours after single intake of 4 capsules of MC. In case of long-term reception of MC (1 capsule twice in day during 4 weeks) the greatest increase in the blood plasma AOA was about 60% (p < 0.001) and was observed on the 14th day. On the 7th day after completion of MC reception the level of blood plasma AOA was, approximately, 20% above its initial value (p < 0.05). This is probably due to prolonged action of MC.
Babenkova
I V
IV
Teselkin
Iu O
IuO
Aseĭchev
A V
AV
Iagmurov
B Kh
BKh
D000328:Adult; D000975:Antioxidants / Q000494:pharmacology*; D001205:Ascorbic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology*; D004338:Drug Combinations; D005419:Flavonoids / Q000494:pharmacology*; D005609:Free Radicals / Q000097:blood; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D010084:Oxidation-Reduction / Q000187:drug effects; D010949:Plasma / Q000187:drug effects* / Q000378:metabolism; D013997:Time Factors
D000975:Antioxidants; D004338:Drug Combinations; D005419:Flavonoids; D005609:Free Radicals; C120252:magnum C; D001205:Ascorbic Acid
Vliianie antioksidantnogo preparata na osnove bioflavonoidov i vitamina C na antioksidantnuiu aktivnost' plazmy krovi.