Heparin and fragments modulate the expression of collagen-degrading enzymes (matrix metalloproteinases 1 and 2) by human gingival fibroblasts.
Hornebeck
W
W
UPRESA 6021 CNRS, Faculté de Médecine, Reims, France.
Gogly
B
B
Godeau
G
G
Emonard
H
H
Pellat
B
B
D002478:Cells, Cultured; D017364:Collagenases / Q000235:genetics*; D005347:Fibroblasts / Q000201:enzymology; D018093:Gelatinases / Q000235:genetics*; D005786:Gene Expression Regulation / Q000187:drug effects; D005881:Gingiva / Q000201:enzymology*; D006493:Heparin / Q000494:pharmacology*; D006801:Humans; D007375:Interleukin-1 / Q000494:pharmacology*; D020781:Matrix Metalloproteinase 1; D020778:Matrix Metalloproteinase 2; D008666:Metalloendopeptidases / Q000235:genetics*; D009844:Oligosaccharides / Q000494:pharmacology; D012333:RNA, Messenger / Q000235:genetics; D012867:Skin / Q000201:enzymology; D014158:Transcription, Genetic / Q000187:drug effects
D007375:Interleukin-1; D009844:Oligosaccharides; D012333:RNA, Messenger; D006493:Heparin; D017364:Collagenases; D018093:Gelatinases; D008666:Metalloendopeptidases; D020778:Matrix Metalloproteinase 2; D020781:Matrix Metalloproteinase 1