Thrombolytic therapy: the treatment of choice for iliac vein thrombosis in the presence of kidney transplant.
A 49-year-old kidney transplant recipient was admitted with the diagnosis of acute iliofemoral deep venous thrombosis (DVT) extending into the external iliac vein in close proximity to the renal vein anastomosis. Thrombolytic therapy with urokinase was used and complete lysis of the thrombus was achieved within 36 hr. We feel that this method of therapy, rather than standard anticoagulation, represents the treatment of choice for acute DVT in the presence of a renal graft. Using this method we were able to salvage the kidney and avoid the complications of postphlebitic syndrome and pulmonary embolus.
University of Massachusetts Medical Center-Memorial Hospital, Worcester, MA 01604, USA.
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Tamim
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Arous
D006801:Humans; D007084:Iliac Vein; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D010960:Plasminogen Activators / Q000627:therapeutic use; D015912:Thrombolytic Therapy; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use; D020246:Venous Thrombosis / Q000188:drug therapy*
D010960:Plasminogen Activators; D014568:Urokinase-Type Plasminogen Activator