Mycobacterium fortuitum infection of ventriculoperitoneal shunt.
Mycobacterium fortuitum is one of the rapidly growing mycobacteria found in soil, dust, and water. It can be isolated as a normal colonizing organism, but as a pathogen this organism causes mainly skin and soft tissue infection preceded by trauma. A wide variety of infections can occur in individuals with predisposing conditions. Central nervous system infection with M fortuitum is rare, and meningitis occurs after surgery or trauma. We believe that ventriculoperitoneal (VP) shunt infection with this organism has not been reported in the literature. Practitioners should be aware of this rare entity and should suspect it in the presence of cerebrospinal fluid pleocytosis with sterile culture, and after trauma, surgery, or manipulation of the VP shunt hardware. Mycobacterium fortuitum is resistant to most first-line and second-line antituberculous drugs, and treatment should include surgical debridement in addition to prolonged antimicrobial therapy.
Department of Pediatrics, Nemours Children's Clinic, University of Florida Health Science Center, Jacksonville 32207, USA.
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Midani
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Rathore
D000293:Adolescent; D000583:Amikacin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D015984:Causality; D002494:Central Nervous System Infections / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003428:Cross Infection / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003646:Debridement; D004322:Drainage; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D019907:Mycobacterium fortuitum; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use; D017287:Ventriculoperitoneal Shunt / Q000009:adverse effects*
D000900:Anti-Bacterial Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D000583:Amikacin