Measuring cerebral blood flow using magnetic resonance imaging techniques.
Magnetic resonance imaging techniques measuring CBF have developed rapidly in the last decade, resulting in a wide range of available methods. The most successful approaches are based either on dynamic tracking of a bolus of a paramagnetic contrast agent (dynamic susceptibility contrast) or on arterial spin labeling. This review discusses their principles, possible pitfalls, and potential for absolute quantification and outlines clinical and neuroscientific applications.
Calamante
F
F
RCS Unit of Biophysics, Institute of Child Health, University College London Medical School, United Kingdom.
Thomas
D L
DL
Pell
G S
GS
Wiersma
J
J
Turner
R
R
D000818:Animals; D002560:Cerebrovascular Circulation; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods