Effect of cadmium-induced lipid peroxidation on EEG spectral components.
Pregnant Swiss albino rats were divided into control (C) and cadmium (Cd) groups. Control animals received tap water while the Cd group received Cd as CdCl2 in their drinking water. The rat pups were separated from their mothers 22 days after birth. 78 young rats were divided into two main groups: controls (C1, C2, C4) and cadmium groups (Cd1, Cd2, Cd4). Each sub-group included 13 rats. On postnatal days 30, 60, and 120, spectral analysis of EEGs recorded from the parietal lobes of all groups of rats was computed by fast Fourier transform (FFT) algorithm. The amplitude maxima were found to occupy the frequency bands of 1-2, 2-4, 4-6, 6-8, 8-16, and 16-30 Hz. The decibel (dB) values of the maxima were significantly decreased in Cd1 and Cd2 groups compared with the corresponding control groups in all the frequency bands except 16-30 Hz. A significant amplitude (dB) decrease was observed in all the frequency bands of the Cd4 group compared with the C4 group.
Department of Physiology, Akdeniz University, Antalya, Turkey.
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A
Ağar
P
P
Yargiçoğlu
U K
UK
Sentürk
V N
VN
Izgüt-Uysal
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism / Q000502:physiology; D002104:Cadmium / Q000378:metabolism / Q000633:toxicity*; D004569:Electroencephalography / Q000187:drug effects*; D005260:Female; D005583:Fourier Analysis; D007668:Kidney / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D051381:Rats; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
D017392:Thiobarbituric Acid Reactive Substances; D002104:Cadmium