Okadaic acid antagonizes the inhibitory action of internal GTP-gamma-S on the calcium current of dorsal raphe neurons but not that of 5-HT1A receptor activation.
Department of Pharmacology, University of Edinburgh, United Kingdom. jskelly@ed.ac.uk
J S
JS
Kelly
H
H
Hećimović
D017371:8-Hydroxy-2-(di-n-propylamino)tetralin / Q000031:analogs & derivatives / Q000494:pharmacology; D000818:Animals; D001464:Barium / Q000378:metabolism; D015220:Calcium Channels / Q000378:metabolism*; D004594:Electrophysiology; D019204:GTP-Binding Proteins / Q000378:metabolism; D016244:Guanosine 5'-O-(3-Thiotriphosphate) / Q000494:pharmacology*; D007700:Kinetics; D008297:Male; D009474:Neurons / Q000187:drug effects; D019319:Okadaic Acid / Q000494:pharmacology*; D010766:Phosphorylation; D011903:Raphe Nuclei / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D011985:Receptors, Serotonin / Q000378:metabolism*; D044263:Receptors, Serotonin, 5-HT1
D015220:Calcium Channels; D011985:Receptors, Serotonin; D044263:Receptors, Serotonin, 5-HT1; D019319:Okadaic Acid; D001464:Barium; D016244:Guanosine 5'-O-(3-Thiotriphosphate); C011799:5-hydroxy-2-N,N-dipropylaminotetralin; D017371:8-Hydroxy-2-(di-n-propylamino)tetralin; D019204:GTP-Binding Proteins