The renal actions of moxonidine are mediated by atrial natriuretic peptide and involve the opioid receptors.
Laboratory of Cardiovascular Biochemistry, Centre Hospitalier de L'Universite de Montreal Research Center, Quebec, Canada. mukaddas@medclin.umontreal.ca
S
S
Mukaddam-Daher
J
J
Gutkowska
D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology*; D009320:Atrial Natriuretic Factor / Q000502:physiology*; D004231:Diuresis / Q000187:drug effects* / Q000502:physiology; D007093:Imidazoles / Q000494:pharmacology*; D007668:Kidney / Q000187:drug effects / Q000502:physiology*; D009271:Naltrexone / Q000494:pharmacology; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D011957:Receptors, Opioid / Q000502:physiology*; D015016:Yohimbine / Q000494:pharmacology
D000959:Antihypertensive Agents; D007093:Imidazoles; D011957:Receptors, Opioid; D015016:Yohimbine; D009271:Naltrexone; D009320:Atrial Natriuretic Factor; C043482:moxonidine