Identification of a novel strain of Borrelia hermsii in a previously undescribed northern California focus.
An epizootiologic investigation testing for the presence of tick-borne relapsing fever spirochetes in rodent and tick hosts was conducted at Eagle Lake in Lassen County, California. Six of 211 O. hermsii ticks and none of 180 rodents were polymerase chain reaction (PCR)-positive for Borrelia spirochetes. Sequencing of the PCR-amplified flagellin gene fragment suggests that the spirochetes from Eagle Lake represent a previously undescribed strain of Borrelia hermsii.
Cleary
M
M
Department of Medical Microbiology, School of Medicine, University of California, Davis 95616, USA.
Theis
J
J
D000818:Animals; D001483:Base Sequence; D001898:Borrelia / Q000145:classification / Q000302:isolation & purification*; D002140:California / Q000453:epidemiology; D017931:DNA Primers / Q000737:chemistry; D004269:DNA, Bacterial / Q000097:blood / Q000737:chemistry / Q000302:isolation & purification; D004587:Electrophoresis, Agar Gel; D005260:Female; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012061:Relapsing Fever / Q000453:epidemiology / Q000662:veterinary*; D012376:Rodent Diseases / Q000453:epidemiology* / Q000469:parasitology; D012589:Sciuridae / Q000469:parasitology; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid; D013987:Ticks / Q000382:microbiology*
D017931:DNA Primers; D004269:DNA, Bacterial