Arterial reconstruction with vascular clips is safe and quicker than sutured repair.
BACKGROUND
Non-penetrating, arcuate-legged vascular-closure staple clips made of titanium were initially developed for microvascular anastomoses with little experience of their use in larger vessels. The purpose of this study was to compare vascular-closure staple clips to sutured anastomoses in common iliac arteries in a porcine model.


METHODS
In an experimental study, transected iliac arteries on both sides of 11 pigs were randomly assigned to end-to-end anastomosis performed with vascular-closure staple clips or interrupted 6-0 polypropylene sutures. Angiographic, macroscopic and microscopic results were assessed after 2 months.


RESULTS
There was no significant difference in the patency rate, tensile strength of the anastomoses, vessel diameter at the repair site, intimal thickness or wall thickness of the arteries after either method of closure. The mean (s.d.) clamp time was 19.8 (6.1) minutes for clip repair, and 36.0 (6.9) seconds for suture repair (P < 0.001). The times required for the reconstruction of the anastomoses were 17.4 (6.1) and 35.5 (7.1) minutes, respectively (P < 0.001).


CONCLUSIONS
Arterial anastomoses performed with vascular-closure staple clips are faster than sutured anastomoses, and result in comparable wound healing when assessed for patency, tensile strength, degree of narrowing and intimal reaction.
Pikoulis
E
E
Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Rhee
P
P
Nishibe
T
T
Leppäniemi
A K
AK
Fishback
N
N
Hufnagel
H V
HV
Wherry
D C
DC
Rich
N M
NM
D000714:Anastomosis, Surgical / Q000295:instrumentation*; D000792:Angiography; D000818:Animals; D005260:Female; D006801:Humans; D007083:Iliac Artery / Q000473:pathology / Q000601:surgery*; D008866:Microsurgery / Q000295:instrumentation*; D013528:Surgical Staplers; D013537:Sutures; D013552:Swine; D014945:Wound Healing / Q000502:physiology