[Craniopharyngioma: clinical, epidemiological and pathological findings in 25 cases].
We report the clinical and pathological findings of 25 cases of craniopharyngiomas. Fourteen patients were males and 11 were females. The ages ranged between 3 and 64 years, with a mean of 30.52 years. The symptoms reflected the growth and topography of the tumours; visual disorders (72%), headache (68%), vomits (40%) and papilledema (24%) were the most frequent symptoms. Twelve cases were suprasellar; 10 tumours arose from sellar region, from which 8 presented suprasellar extension; frontal lobe (n = 2) and ponto cererebellar angle (n = 1) were also affected. Eleven patients undergone total resection of the tumor and 14 were submitted to partial resection, from which 1 received adjuvant chemotherapy. The overall recurrence rate was 48%. Eight recurrences were observed in the patients submitted to partial resection and 4 in which total resection were performed. These results are similar with the literature, corroborating to the extension of residual tumour after the surgical resection as the main prognostic factor for this neoplasm.
Serviço de Anatomia Patológica (SAP), Hospital de Clínicas (HC) da Universidade Federal do Paraná (UFPR), Curitiba, PR, Brasil. bleggi@hc.ufpr.br e lftorres@uol.com.br
L F
LF
Torres
J S
JS
Reis Filho
M R
MR
Netto
L A
LA
Dellé
B G
BG
Sluminsky
L N
LN
Faoro
A
A
Antoniuk
R
R
Ramina
D000328:Adult; D002648:Child; D002675:Child, Preschool; D003397:Craniopharyngioma / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010911:Pituitary Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery
Craniofaringiomas. Achados clínicos, epidemiológicos e anatomopatológicos de 25 casos.