Ontogeny of recurrent hydrocephalus: presentation in three fetuses in one consanguineous family.
A consanguineous couple had 3 pregnancies in which prenatally diagnosed hydrocephalus was observed (in 1 female and 2 male fetuses). This case appears to represent an autosomal recessive form of hydrocephalus, given the consanguinity, affected sibs of both genders, and no evidence for intrauterine infection, chromosome abnormality, or neural tube defect.
Division of Reproductive Genetics, Department of Obstetrics and Gynecology, Wayne State University/Hutzel Hospital, Detroit, Mich. 48201, USA.
T B
TB
Brady
R L
RL
Kramer
F
F
Qureshi
B
B
Feldman
W J
WJ
Kupsky
M P
MP
Johnson
M I
MI
Evans
D000328:Adult; D002552:Cerebral Ventricles / Q000002:abnormalities; D003241:Consanguinity; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D010375:Pedigree; D011247:Pregnancy; D011296:Prenatal Diagnosis