[Site specific difference of PCB concentration in the skin derived sebum and collection of excreted sebum with commercial sebum-remover sheet].
The PCB concentrations in the sebum of Yusho patients showed a site specific difference. It was higher in the sebum derived from the chest (1128.0 +/- 374.1 ng/g), the upper arm (1460.0 +/- 350.7 ng/g) and the femur (1456.0 +/- 488.5 ng/g) than from the forehead (758.0 +/- 233.7 ng/g) and the upper back skin (638.0 +/- 165.3 ng/g). To remove PCB in the sebum, a sebum-remover sheet was applied on the femur of two patients. During the four times of application, the mean amounts of removed sebun was 10.5 mg and 28.3 mg respectively. These results are unsatisfactory for practical treatment of Yusho patient. However, this approach seems to be safe and convenient and modification to collect large scale of sebum from the skin is required.
Department of Dermatology, Nagasaki University School of Medicine, Sakamoto.
M
M
Watanabe
F
F
Ogawa
I
I
Katayama
Y
Y
Tokusue
D000368:Aged; D000369:Aged, 80 and over; D001132:Arm; D001415:Back; D005260:Female; D005269:Femur; D005506:Food Contamination; D005546:Forehead; D006801:Humans; D008297:Male; D012275:Oryza / Q000506:poisoning; D010938:Plant Oils / Q000506:poisoning; D011078:Polychlorinated Biphenyls / Q000032:analysis* / Q000506:poisoning; D012629:Sebum / Q000737:chemistry*; D012867:Skin / Q000737:chemistry*; D013048:Specimen Handling / Q000379:methods*
D010938:Plant Oils; D011078:Polychlorinated Biphenyls