Bisphosphonates in children with osteogenesis imperfecta may improve bone mineralization but not bone strength. Report of two patients.
Roldán
E J
EJ
Pediatrics Department and Endocrinology Service, Italian Hospital, Buenos Aires, Argentina.
Pasqualini
T
T
Plantalech
L
L
D015502:Absorptiometry, Photon; D001696:Biomechanical Phenomena; D015519:Bone Density; D001842:Bone and Bones / Q000503:physiopathology*; D002648:Child; D004164:Diphosphonates / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010013:Osteogenesis Imperfecta / Q000188:drug therapy* / Q000503:physiopathology; D000077268:Pamidronate; D013718:Tensile Strength; D014057:Tomography, X-Ray Computed; D019415:Torque
D004164:Diphosphonates; D000077268:Pamidronate