Autoimmunity: Another pathway towards arthritis.
A new pathway leading to arthritis has been revealed by the discovery that antibodies specific for a ubiquitously expressed antigen are able to transfer a severe arthritic phenotype in mice. This new model will be useful for further analyses of the different pathways involved in rheumatoid arthritis.
Lund University, Section for Medical Inflammation Research, Sölvegatan 19, 22362, Lund, Sweden. Rikard.Holmdahl@inflam.lu.se
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D000818:Animals; D001168:Arthritis / Q000209:etiology* / Q000235:genetics / Q000276:immunology*; D015551:Autoimmunity; D004195:Disease Models, Animal; D005802:Genes, MHC Class II / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D051379:Mice; D008822:Mice, Transgenic; D010641:Phenotype
D007074:Immunoglobulin G