[Indicators of lipid peroxidation in rat liver mitochondria after exposing them to some xenobiotics and the action of low dose radiation].
The contents of primary and secondary products of lipid peroxidation in rat liver mitochondria through 1, 7 and 15 days after gamma-irradiation in a dose 0.5 Gy on a background of consumption of sodium nitrate, sodium nitrite and nitrosodiethylamine was investigated. Is was shown, that gamma-irradiation on a background of sodium nitrate, sodium nitrite and nitrosodiethylamine modified effects of nitrocompounds on speed of lipid peroxidation. Besides, combine action of sodium nitrate and gamma-irradiation has more effect in comparison with influencing of separate factors. The observed changes in quantity of lipid peroxidation products are rather stable and are kept during all terms of supervision.
Belarussian State University, Minsk.
I A
IA
Kanapatskaia
T N
TN
Zyrianova
V M
VM
Lavrova
D000818:Animals; D004052:Diethylnitrosamine / Q000494:pharmacology; D015227:Lipid Peroxidation; D008930:Mitochondria, Liver / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D009566:Nitrates / Q000494:pharmacology; D011829:Radiation Dosage; D051381:Rats; D012977:Sodium Nitrite / Q000494:pharmacology; D015262:Xenobiotics / Q000494:pharmacology*
D009566:Nitrates; D015262:Xenobiotics; D004052:Diethylnitrosamine; C031618:sodium nitrate; D012977:Sodium Nitrite
Pokazateli peroksidnogo okisleniia lipidov v titokhondriiakh pecheni krys posle vvedeniia im nekotorykh ksenobiotikov i deĭstviia radiatsii v maloĭ doze.