Tandem mass spectrometry--the potential.
We summarize the current status of the use of tandem mass spectrometry for the detection of inherited metabolic disorders and the investigation of the pathophysiology of these conditions. We also indicate some of the more recent developments of this technology that have potential diagnostic applications.
Spence Biochemical Genetics Unit, Sir James Spence Institute of Child Health, University of Newcastle upon Tyne, Royal Victoria Infirmary, UK. kim.bartlett@ncl.ac.uk
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Pourfarzam
D006801:Humans; D013058:Mass Spectrometry; D008661:Metabolism, Inborn Errors / Q000175:diagnosis*