Tetracycline derivative CMT-3 inhibits cytokine production, degranulation, and proliferation in cultured mouse and human mast cells.
Department of Medical Chemistry, Helsinki University Hospital, Finland.
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Eklund
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Sorsa
D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology; D000001:Calcimycin / Q000494:pharmacology; D015550:Cell Degranulation / Q000187:drug effects* / Q000502:physiology; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D002478:Cells, Cultured; D017077:Culture Media, Conditioned; D016207:Cytokines / Q000096:biosynthesis*; D006801:Humans; D008407:Mast Cells / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D051379:Mice; D008807:Mice, Inbred BALB C; D011480:Protease Inhibitors / Q000494:pharmacology*; D013754:Tetracyclines / Q000494:pharmacology*; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology
D017077:Culture Media, Conditioned; D016207:Cytokines; D011480:Protease Inhibitors; D013754:Tetracyclines; C117155:tetracycline CMT-3; D000001:Calcimycin; D013755:Tetradecanoylphorbol Acetate