Synthesis of glucosylated 1,2,3-triazole derivatives.
A series of potential bioactive compounds, 1-glucosyl-4-heterocyclyl-5-(p-substituted-phenyl)-1,2,3-triazoles , were synthesized. Highly stereoselective products were obtained in good yield. Primary activity screening showed that this type of N-glucosylic compound possessed antitumour and antiviral activities.
Institute of Chemistry, Chinese Academy of Sciences, Beijing, PR China.
X M
XM
Chen
Z J
ZJ
Li
Z X
ZX
Ren
Z T
ZT
Huang
D005947:Glucose / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D013696:Temperature; D014230:Triazoles / Q000138:chemical synthesis*
D014230:Triazoles; D005947:Glucose