[Uremic hemolytic syndrome. Analysis of 43 cases].
OBJECTIVE
The purpose of this study was to describe the epidemiological, clinical and evolution features of hemolytic uremic syndrome (HUS).


METHODS
A retrospective study of 43 cases of HUS during the last 14 years (1984-1998) was performed.


RESULTS
The mean age of the patients was 3.2 years, the incidence during the summer season was the highest and 39 cases (90%) previously had acute gastroenteritis. All children had acute renal failure, 32 of them (74%) required peritoneal dialysis. Anuria was found in 22 case (51%) and the mean duration was 10.3 days. The most frequent complications were: Hypertension in 21 cases (48%), peritonitis in 9 cases (20%), seizures in 8 patients (16%) and 3 deaths (6%). The mean hospital stay was 14.5 days. After one year of ambulatory control, 76% of the children were completely recovered and only two cases (6%) had chronic renal failure. Seizures associated significantly with a bad prognosis (p < 0.05).


CONCLUSIONS
HUS has a very important morbimortality. Seizures in the acute phase were associated with a bad prognosis. Anuria for more than 7 days and oliguria for more than 15 days were also predictors of a worse prognosis, but this was not significant.
Servicio de Cuidados Intensivos Pediátricos, Hospital del Niño Jesús, Madrid.
S
S
Mencía Bartolomé
A
A
Martínez de Azagra
A
A
de Vicente Aymat
M
M
Monleón Luque
J
J
Casado Flores
D058186:Acute Kidney Injury / Q000209:etiology / Q000628:therapy; D002675:Child, Preschool; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D008297:Male; D010530:Peritoneal Dialysis / Q000379:methods; D011379:Prognosis; D012189:Retrospective Studies; D012621:Seasons; D013030:Spain / Q000453:epidemiology
Síndrome hemolítico urémico. Análisis de 43 casos.