Cell polarity: Versatile scaffolds keep things in place.
Protein scaffolds organize transmembrane and cytoplasmic proteins and serve to integrate both structure and signaling at the apical junctional complex of polarized epithelial cells. These scaffolds are important in coordinating local and global changes in cell organization.
Department of Molecular and Cellular Physiology, Beckman Center for Molecular and Genetic Medicine, Stanford University School of Medicine, Stanford, California 94305-5345, USA.
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Yeaman
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Grindstaff
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Hansen
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Nelson
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D016764:Cell Polarity; D003593:Cytoplasm / Q000502:physiology; D004330:Drosophila; D029721:Drosophila Proteins; D004847:Epithelial Cells / Q000502:physiology*; D019476:Insect Proteins / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D008954:Models, Biological; D009154:Mutation; D015398:Signal Transduction
D029721:Drosophila Proteins; D019476:Insect Proteins; D008565:Membrane Proteins; C064360:crb protein, Drosophila; C118488:dlt protein, Drosophila