[Prevalence of coronary risk factors in 233 men with coronary heart disease. Role of HDL cholesterol].
In 233 male patients (age 35 to 90 years) with coronary heart disease, chiefly myocardial infarction, the prevalence of the established coronary risk factors was investigated: total cholesterol, HDL- and LDL-cholesterol, triglycerides, hypertension, smoking, overweight, diabetes, heredity, physical inactivity and psychosocial stress. Cigarette smoking shows the highest prevalence (54%), followed by hypertension (39%), overweight (38.6%) and hypercholesterolaemia (34.7%). In patients over 65 the prevalence of these coronary risk factors is lower, whereas physical inactivity and diabetes are more frequent than in the younger group. Combinations of the main coronary risk factors are much more frequent in the younger group. HDL-cholesterol was found to be lower than normal (below 0.91 mmol/l) in 27% irrespective of age. The lower the concentration of HDL-cholesterol the more frequent are the following coronary risk factors: smoking, overweight, diabetes, physical inactivity and hypertriglyceridaemia. We suspect that a low HDL-cholesterol concentration in many individuals may be the result of a clustering of the aforementioned risk factors. For practical purposes it seems important to evaluate all relevant risk factors in an individual and to concentrate intervention on those with a fair chance of success, especially smoking and hypertension in the younger subjects. Normal or elevated HDL-cholesterol in itself is not a reliable cardioprotective factor since it is normal or elevated in two thirds of our coronary heart disease patients.
Hartmann
G
G
Medizinische Klinik, Rätisches Kantonsspital Chur.
Schmid
R
R
D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D008076:Cholesterol, HDL / Q000097:blood / Q000502:physiology*; D003327:Coronary Disease / Q000097:blood / Q000453:epidemiology*; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D013557:Switzerland
D008076:Cholesterol, HDL; D008055:Lipids
Prävalenz von koronaren Risikofaktoren bei 233 Männern mit koronarer Herzkrankheit. Rolle des HDL-Cholesterins.