Thrombotic thrombocytopenic purpura as an initial presentation of limited systemic sclerosis.
Thrombotic thrombocytopenic purpura (TTP) is a rare complication of scleroderma (systemic sclerosis, SSc). In the 5 reports documenting the association of TTP and SSc, the TTP syndrome developed on a background of well established SSc. We describe a 51-year-old woman with a 5 month history of an evolving connective tissue disease syndrome who presented initially with TTP, followed 4 months later by limited cutaneous SSc and Raynaud's phenomenon.
Towheed
T E
TE
Department of Medicine and Community Health, Queen's University, Kingston, Canada.
Anastassiades
T P
TP
Ford
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SE
Ford
P M
PM
Lee
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P
D001921:Brain / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008875:Middle Aged; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology*; D012595:Scleroderma, Systemic / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed