Detection and identification of morphine in urine extracts using thin-layer chromatography and tandem mass spectrometry.
The application of tandem mass spectrometry to the analysis and identification of morphine following thin-layer chromatography is described. FAB-mass spectrometry and mass spectrometry-mass spectrometry were performed following chromatography on silica gel high-performance thin-layer chromatography plates. The successful application of this simple methodology to a urine extract suggests that this approach has practical utility for confirming the identity of abused drugs detected by thin-layer chromatography.
Dept. Clinical Biochemistry, University Hospital, Aintree, Liverpool, UK.
F
F
Tames
I D
ID
Watson
W
W
Morden
I D
ID
Wilson
D002855:Chromatography, Thin Layer / Q000379:methods*; D006801:Humans; D009020:Morphine / Q000652:urine*; D012015:Reference Standards; D016339:Spectrometry, Mass, Fast Atom Bombardment / Q000379:methods*
D009020:Morphine