Selection of patients for carotid endarterectomy.
OBJECTIVE
The aim of this study was the definition of the duplex scan parameters that best select patients for carotid endarterectomy.


METHODS
This study was set in a regional vascular unit. Duplex scanning and angiography were performed prospectively on 50 patients who were symptomatic (100 carotid bifurcation) to identify the most accurate and sensitive duplex scan criteria to identify an 80% to 99% stenosis according to the European Carotid Symptomatic Trial. With data from the European Carotid Symptomatic Trial, we estimated the effect of three different approaches used to select patients for carotid endarterectomy. The first approach was the selection of patients for carotid surgery on the basis of duplex scanning alone with the most accurate duplex scan criteria (approach I). The second approach was the selection of patients for carotid surgery on the basis of duplex scanning alone with a 100% sensitive duplex scan criteria (approach II). The third approach was the selection of patients for angiography with duplex scanning (100% sensitive criteria) and then the use of angiography to define which patients should undergo surgery (approach III).


RESULTS
All three approaches appeared to have a similar potential in stroke reduction. However, approach I, which minimized the number of patients who underwent surgery (19% less than approach II) or invasive imaging (65% less than approach III), appeared to be the most appropriate.


CONCLUSIONS
These data support the selection of patients for carotid endarterectomy on the basis of duplex scanning alone. The duplex scan criteria should be validated against angiography.
Golledge
J
J
Imperial College of Science Technology & Medicine, Department of Surgery and Radiology, Charing Cross Hospital, London, UK.
Ellis
M
M
Sabharwal
T
T
Sikdar
T
T
Davies
A H
AH
Greenhalgh
R M
RM
D000368:Aged; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging; D016893:Carotid Stenosis / Q000000981:diagnostic imaging / Q000601:surgery*; D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000517:prevention & control; D016894:Endarterectomy, Carotid; D005260:Female; D006801:Humans; D008297:Male; D018579:Patient Selection; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D018616:Ultrasonography, Doppler, Duplex