The influence of supplements of selenite, selenate and selenium yeast on the selenium status of dairy heifers.
The aim of the study was to define possible differences between selenite, selenate and selenium yeast on various aspects of selenium status in growing cattle. Twenty-four Swedish Red and White dairy heifers were fed no supplementary selenium for 6 months. The basic diet contained 0.026 mg selenium/kg feed dry matter (DM). After the depletion period the animals were divided into 4 groups; group I-III received 2 mg additional selenium daily as sodium selenite, sodium selenate, and a selenium yeast product, respectively. Group IV, the control group, received no additional selenium. The total dietary selenium content for groups I-III during the supplementation period was 0.25 mg/kg DM. After the depletion period the mean concentration of selenium in blood (640 nmol/l) and plasma (299 nmol/l) and the activity of GSH-Px in erythrocytes (610 mukat/l) were marginal, but after 3 months of supplementation they were adequate in all 3 groups. The concentration of selenium in blood and plasma was significantly higher in group III than in groups I and II, but there was no significant difference between groups I and II. The activity of GSH-Px in erythrocytes did not differ between any of the supplemented groups. The animals in the control group had significantly lower concentrations of selenium in blood and plasma and lower activities of GSH-Px in erythrocytes than those in the supplemented groups. The activity of GSH-Px in platelets was also increased by the increased selenium intake. There was no difference in the concentration of triiodothyronine (T3) between any of the groups, but the concentration of thyroxine (T4) was significantly higher in the unsupplemented control group.
Department of Animal Environment and Health, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala, Sweden. K.Ortman@hmh.slu.se
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K
Ortman
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R
Andersson
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H
Holst
D000818:Animals; D001792:Blood Platelets / Q000737:chemistry; D002417:Cattle; D005260:Female; D005979:Glutathione Peroxidase / Q000032:analysis; D016566:Organoselenium Compounds / Q000378:metabolism*; D011863:Radioimmunoassay / Q000662:veterinary; D011897:Random Allocation; D064586:Selenic Acid; D012643:Selenium / Q000097:blood / Q000502:physiology*; D018036:Selenium Compounds / Q000378:metabolism*; D018038:Sodium Selenite / Q000378:metabolism*; D013054:Spectrophotometry, Atomic / Q000662:veterinary; D013974:Thyroxine / Q000097:blood / Q000378:metabolism; D014284:Triiodothyronine / Q000097:blood / Q000378:metabolism
D016566:Organoselenium Compounds; D018036:Selenium Compounds; D014284:Triiodothyronine; D005979:Glutathione Peroxidase; D012643:Selenium; D018038:Sodium Selenite; D064586:Selenic Acid; D013974:Thyroxine