Measuring cerebral blood flow using magnetic resonance imaging techniques.
Magnetic resonance imaging techniques measuring CBF have developed rapidly in the last decade, resulting in a wide range of available methods. The most successful approaches are based either on dynamic tracking of a bolus of a paramagnetic contrast agent (dynamic susceptibility contrast) or on arterial spin labeling. This review discusses their principles, possible pitfalls, and potential for absolute quantification and outlines clinical and neuroscientific applications.
RCS Unit of Biophysics, Institute of Child Health, University College London Medical School, United Kingdom.
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F
Calamante
D L
DL
Thomas
G S
GS
Pell
J
J
Wiersma
R
R
Turner
D000818:Animals; D002560:Cerebrovascular Circulation; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods