Hemodynamic abnormalities in sodium monofluoroacetate intoxication.
Hypotension is one of the most important predictors of mortality in sodium monofluoroacetate (SMFA) intoxication. This paper reports the hemodynamic response in one fatal and another survival case of SMFA intoxication. Despite correction of hypovolemia and with inotropic support, the patients remained in shock. Hemodynamic observations have provided evidence that shock after SMFA intoxication is due to diminished systemic vascular resistance and increased cardiac output. This is the first report in which such an invasive hemodynamic investigation has been recorded in a clinical case of SMFA intoxication.
Department of Emergency Medicine, National Cheng-Kung University Medical College and Hospital, Tainan City, Taiwan.
C H
CH
Chi
T K
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Lin
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KW
Chen
D000328:Adult; D002302:Cardiac Output / Q000187:drug effects*; D002319:Cardiovascular System / Q000187:drug effects / Q000378:metabolism; D005260:Female; D005463:Fluoroacetates / Q000506:poisoning*; D006801:Humans; D008875:Middle Aged; D012378:Rodenticides / Q000506:poisoning*; D012769:Shock / Q000139:chemically induced* / Q000503:physiopathology*; D014655:Vascular Resistance / Q000187:drug effects*
D005463:Fluoroacetates; D012378:Rodenticides; C014815:fluoroacetic acid