Cholinergic, M1 receptors in the nucleus accumbens mediate behavioral depression. A possible downstream target for fluoxetine.
Chau
D
D
Department of Psychology, Princeton University, New Jersey 08544, USA.
Rada
P V
PV
Kosloff
R A
RA
Hoebel
B G
BG
D017371:8-Hydroxy-2-(di-n-propylamino)tetralin / Q000008:administration & dosage / Q000494:pharmacology; D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D001115:Arecoline / Q000008:administration & dosage / Q000494:pharmacology; D003863:Depression / Q000503:physiopathology*; D005260:Female; D005473:Fluoxetine / Q000008:administration & dosage / Q000494:pharmacology*; D008845:Microinjections; D009043:Motor Activity / Q000187:drug effects / Q000502:physiology*; D009714:Nucleus Accumbens / Q000187:drug effects / Q000502:physiology* / Q000503:physiopathology; D010890:Pirenzepine / Q000008:administration & dosage / Q000494:pharmacology; D011187:Posture; D051381:Rats; D017207:Rats, Sprague-Dawley; D043643:Receptor, Muscarinic M1; D011976:Receptors, Muscarinic / Q000187:drug effects / Q000502:physiology*; D012601:Scopolamine / Q000008:administration & dosage / Q000494:pharmacology; D013550:Swimming
D043643:Receptor, Muscarinic M1; D011976:Receptors, Muscarinic; D005473:Fluoxetine; D010890:Pirenzepine; D001115:Arecoline; D017371:8-Hydroxy-2-(di-n-propylamino)tetralin; D012601:Scopolamine; D000109:Acetylcholine