Anatomy of sensory findings in patients with posterior cerebral artery territory infarction.
BACKGROUND
Posterior cerebral arteries (PCAs) supply the ventrolateral thalamic sensory nuclei and white matter sensory tracts to the somatosensory parietal cortex. Patients with PCA territory strokes often have visual, memory, cognitive, and sensory signs. Clinicoanatomic correlation of visual, cognitive, and memory functions are well defined but, to our knowledge, no systematic study has analyzed the anatomy of sensory abnormalities.


OBJECTIVE
To assess the frequency and anatomic correlation of sensory symptoms and signs in patients with PCA territory infarction.


METHODS
Sixty patients with hemispheral and hemispheral and deep PCA territory infarcts apparent on computed tomographic and magnetic resonance imaging scans were studied for the presence of sensory findings and location of infarcts.


RESULTS
Sensory symptoms or signs were present in 15 (25%) of 60 patients. Among patients with sensory findings, 11 of 15 had infarcts in the ventrolateral thalamus in the territory of the thalamogeniculate or lateral posterior choroidal arteries. The other 4 patients had no ventrolateral thalamic or white matter infarction but had severe proximal vascular occlusive lesions that could have caused temporary thalamic ischemia. One of these 4 patients had a medial thalamic infarct and transient hemisensory symptoms. Twelve patients had thalamic infarcts and no recorded sensory findings. Seven patients with thalamic infarcts (6 medial and 1 ventrolateral) had no sensory findings, and sensory findings could not be accurately assessed in 4 patients with ventrolateral and 1 patient with medial thalamic infarcts.


CONCLUSIONS
All patients with PCA territory infarcts and sensory findings either had thalamic infarcts in thalamogeniculate or lateral posterior choroidal artery territory or had thalamic ischemia. Sensory findings in PCA territory infarction indicate ventrolateral thalamic ischemia.
Department of Neurology, Kiel University Hospital, Germany.
A L
AL
Georgiadis
Y
Y
Yamamoto
E S
ES
Kwan
M S
MS
Pessin
L R
LR
Caplan
D002539:Cerebral Arterial Diseases / Q000150:complications* / Q000175:diagnosis; D002544:Cerebral Infarction / Q000175:diagnosis / Q000209:etiology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008569:Memory Disorders / Q000175:diagnosis / Q000209:etiology; D008875:Middle Aged; D010296:Parietal Lobe / Q000098:blood supply* / Q000473:pathology; D012189:Retrospective Studies; D013003:Somatosensory Cortex / Q000503:physiopathology*; D013787:Thalamic Nuclei / Q000098:blood supply* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014786:Vision Disorders / Q000175:diagnosis / Q000209:etiology