Conjunctival melanocytic nevi of childhood.
Two young patients with conjunctival compound nevi are presented to illustrate two types of abnormalities that lead to difficulty in distinction of these nevi from invasive melanomas. In Case 1, inflammation is associated with disruption of the nevus cell architecture and cytologic atypia. In Case 2, the occurrence of a combined nevus (compound and blue nevus types) in the conjunctiva leads to diagnostic problems. Circumscription of the lesions, lack of mitoses in the substantia propria, and lack of pagetoid spread of atypical cells in the adjacent conjunctival epithelium support benign diagnoses in both cases.
Department of Pathology, Osmangazi University Hospital, Eskişehir, Turkey.
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Kabukçuoğlu
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McNutt
D000293:Adolescent; D002648:Child; D003230:Conjunctival Neoplasms / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007249:Inflammation / Q000473:pathology; D018329:Nevus, Blue / Q000473:pathology; D009508:Nevus, Pigmented / Q000473:pathology*