Pregnancies after activated oocyte transfer: a new option for infertility treatment.
In this preliminary report, we describe a new technique involving the same-day transfer of activated oocytes to the uterus after intracytoplasmatic sperm injection (ICSI). The technique, termed activated oocyte transfer (AOT), offered to 19 couples, yielded a pregnancy rate per cycle of about 30%, equivalent to traditional in-vitro fertilization (IVF) and ICSI in a laboratory setting. AOT is performed 4 h after oocyte retrieval, permitting the patient to undergo treatment as an out-patient procedure.
Biologia della Riproduzione, Clinica Villa del Sole, Via Manzoni, 15, Naples 80123, Italy.
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B
Dale
A
A
Fiorentino
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R
De Stefano
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L
Di Matteo
M L
ML
De Simone
M
M
Wilding
F
F
Zullo
D000328:Adult; D003593:Cytoplasm; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007248:Infertility, Male / Q000628:therapy*; D008297:Male; D008845:Microinjections; D009865:Oocytes; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D013094:Spermatozoa