Synchronous pleomorphic adenomas of the major salivary glands: a case report.
The presentation of multiple distinct tumors in major salivary glands is rare. Although the most common tumor with bilateral synchronous or metachronous development is the Warthin tumor, pleomorphic adenomas have been diagnosed simultaneously as well. We report the case of a female patient who was diagnosed with pleomorphic adenomas in the right parotid and submandibular glands, concomitant with sialolithiasis affecting the submandibular gland. This patient had been exposed to head and neck radiotherapy in childhood, which may have played a role in the development of her tumors. A review of the relevant literature is included.
Department of Oral & Maxillofacial Surgery, Faculty of Medicine, Rambam Medical Center and Technion-Israel Institute of Technology, Haifa.
R M
RM
Nagler
D
D
Laufer
D008949:Adenoma, Pleomorphic / Q000150:complications / Q000473:pathology*; D016371:Cranial Irradiation / Q000009:adverse effects; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000209:etiology / Q000473:pathology; D010307:Parotid Neoplasms / Q000150:complications / Q000473:pathology*; D012793:Sialadenitis / Q000150:complications; D013364:Submandibular Gland Diseases / Q000150:complications; D013365:Submandibular Gland Neoplasms / Q000150:complications / Q000473:pathology*