[Goblet cells density of bulbar conjunctiva after long-term topical antiglaucoma agents].
OBJECTIVE
The purpose of this study was to determine the effect of long-term topical antiglaucoma therapy on goblet cells density of the bulbar conjunctiva.


METHODS
Conjunctiva impression cytology specimens from 59 glaucoma patients and 30 healthy people were assessed quantitatively by light microscopy. Patients with glaucoma were on a stable regimen of one (beta-blocker alone) or two (beta-blocker with miotic) topically administered medications for a minimum 1-year.


RESULTS
The results show statistically significant decrease in goblet cells associated with number of antiglaucoma drugs and duration of treatment.


CONCLUSIONS
Long-term topical antiglaucoma treatment decrease goblet cells population of bulbar conjunctiva.
Wróblewska
E
E
II Kliniki Okulistyki AM w Lublinie.
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology* / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002452:Cell Count / Q000187:drug effects; D003228:Conjunctiva / Q000187:drug effects* / Q000473:pathology*; D005260:Female; D005901:Glaucoma / Q000188:drug therapy*; D020397:Goblet Cells / Q000187:drug effects* / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors
D000319:Adrenergic beta-Antagonists
Liczba komórek kubkowych w spojówce gałkowej po długotrwałym stosowaniu leków przeciwjaskrowych.