[The influence of hypokinesia on the mother-fetus system].
In experiments with rats effects of hypokinesia on the course of pregnancy and the mother-fetus system were investigated. Immobilization in penal-type cages of female rats on days 8 through to 19 of pregnancy gave rise to significant shifts in mother's organism, i.e. retarded body mass gain, mass reductions in thymus, spleen, liver, some other organs, and adipose tissue. Rates of prenatal fatality in the experimental group were not changed; yet, fetuses were behind the control by the values of body mass, ossification ranges, development of analyzers and other parameters. Quantities of liquid, sodium, magnesium and calcium per one gram of dry tissue were equal in the experimental and control fetuses. Comparison of the data with results of the embryological experiment with rats aboard the space "shuttle" suggests that immobilization is more baneful for the mother-fetus system than microgravity of the same length.
Serova
L V
LV
Shakhmatova
E I
EI
Savel'ev
S V
SV
Besova
N V
NV
Nosovskiĭ
A M
AM
Chel'naia
N A
NA
D000818:Animals; D005260:Female; D005313:Fetal Death; D018476:Hypokinesia / Q000196:embryology*; D008431:Maternal-Fetal Exchange / Q000502:physiology*; D011247:Pregnancy; D051381:Rats; D013026:Space Flight; D014893:Weightlessness
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