[Combination therapy of high frequency oscillatory ventilation, NO inhalation and surfactant replacement in a child with acute respiratory distress syndrome].
We report about a child with severe ARDS after burning trauma who did not respond to conventional treatment with controlled pressure ventilation under conditions of permissive hypercapnia and changing of the infants's body position. A combined treatment with high frequency oscillatory ventilation, inhalation of nitric oxide and surfactant replacement improved the pulmonary status. Twelve days after the accident the boy could be extubated and 5 weeks later he could be discharged without any pulmonary and neurologic handicap. The use of these therapeutic tools may help to avoid the necessity of the invasive extracorporeal life support.
Kinderklinik, Neonatologische Intensivemedizin Universitätsklinikums RWTH Aachen.
U
U
Merz
J
J
Schefels
H
H
Hendricks
H
H
Hörnchen
D000208:Acute Disease; D000280:Administration, Inhalation; D002056:Burns / Q000150:complications; D002675:Child, Preschool; D003131:Combined Modality Therapy; D006612:High-Frequency Ventilation / Q000379:methods*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009569:Nitric Oxide / Q000627:therapeutic use*; D011663:Pulmonary Surfactants / Q000627:therapeutic use*; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome
D011663:Pulmonary Surfactants; D009569:Nitric Oxide
Kombinierter Einsatz von Hochfrequenzoszillationsbeatmung, NO-Applikation und Surfactantsubstitution beim kindlichen ARDS.