Heterophile antibodies to bovine and caprine proteins causing false-positive human immunodeficiency virus type 1 and other enzyme-linked immunosorbent assay results.
Heterophile antibodies are a well-recognized cause of erroneous results in immunoassays. We describe here a 22-month-old child with heterophile antibodies reactive with bovine serum albumin and caprine proteins causing false-positive results to human immunodeficiency virus type 1 and other infectious serology testing.
Willman
J H
JH
Division of Clinical Pathology, Department of Pathology, University of Utah, ARUP Laboratories and the ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84132, USA.
Martins
T B
TB
Jaskowski
T D
TD
Hill
H R
HR
Litwin
C M
CM
D000818:Animals; D000910:Antibodies, Heterophile / Q000032:analysis* / Q000276:immunology; D000956:Antigens, Viral / Q000032:analysis / Q000276:immunology; D002417:Cattle; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D006041:Goats / Q000097:blood* / Q000276:immunology; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D007223:Infant; D008297:Male; D008894:Milk Proteins / Q000276:immunology; D012709:Serum Albumin / Q000276:immunology*
D000910:Antibodies, Heterophile; D000956:Antigens, Viral; D008894:Milk Proteins; D012709:Serum Albumin