[Etiopathogenesis and management of paraneoplastic fever and Stauffer syndrome in renal carcinoma].
Some paraneoplastic syndromes as fever, cachexia, loss of weight or hepatic dysfunction, are relatively frequent in patients affected by a renal cell carcinoma (RCC). However their pathogeny has been unknown until a short time ago. The advances in immunology have permitted to identify the interleukin-6 as the responsible for these changes. In spite of our better knowledge, the treatment of these paraneoplastic syndromes, when persist after the removal of the tumor, continues being a challenge. We present the case of a patient with a renal cell carcinoma that began as a feverish syndrome, developing thereinafter a hepatic dysfunction or Stauffer's syndrome. The paraneoplastic symptoms persisted after removal of the tumor. No response to the administered treatment has been observed. The patient died two months after the surgery.
Servicio de Urología, Hospital Son Dureta, Palma de Mallorca, Baleares.
D
D
Muñoz Vélez
M
M
Rebasa Llull
F
F
Hidalgo Pardo
V
V
Riera Marí
A
A
Mus Malleu
C
C
Gutiérrez Sanz-Gadea
M
M
Ozonas Moragues
D002292:Carcinoma, Renal Cell / Q000150:complications*; D005334:Fever / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications*; D008107:Liver Diseases / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology* / Q000628:therapy*; D013577:Syndrome
Etiopatogenia y manejo de la fiebre paraneoplásica y del síndrome de Stauffer en el carcinoma renal.