[Nasopharyngeal carriage of resistance pneumococci in day-care centers in the Alps-Maritimes region].
To provide ongoing information on regional trends of antibiotic resistance prevalence to pneumococci, a cross selectional survey was conducted on a large representative sample of children attending day-care centers. Children were analyzed in spring (n = 378) and autumn (n = 379) for nasopharyngeal carriage. Streptococcus pneumoniae was detected in 149 children (39.4%) in Spring and 204 (59.8%) in Autumn. Half of these isolated strains showed penicillin insensitivity or resistance. A high proportion of children (43.6% in spring and 47.5% in autumn) had been treated with antibiotics during the 3 months prior to sample collection; 21.6% of isolated strains were serotype 6B, 20.1% type 23F, 18.9% type 19A and 19F, 11.5% type 14. Reduced susceptibility was frequently noted in serotype 23F, 14 and 19F, representing 93%, 94% and 46% of identified serotypes, respectively. Acquisition of a strain of PRP was correlated with prescription of antibiotics during the previous three months (p < 0.05). This type of survey on children in day-care centers can contribute to the understanding of regional variations in antibiotic resistance and provide information for epidemiological surveillance.
CISIH de Nice, Hôpital l'Archet, Nice, France.
C
C
Pradier
B
B
Dunais
H
H
Carsenti-Etesse
P
P
Cavailler
H
H
Haas
L
L
Boutin-Andreu
P
P
Dellamonica
D000818:Animals; D002656:Child Day Care Centers; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission; D004352:Drug Resistance, Microbial; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D009297:Nasal Mucosa / Q000382:microbiology*; D010403:Penicillin Resistance; D010614:Pharynx / Q000382:microbiology*; D011008:Pneumococcal Infections / Q000453:epidemiology / Q000635:transmission*; D012307:Risk Factors; D012703:Serotyping; D012907:Smoking; D013296:Streptococcus pneumoniae / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification*
Portage nasopharyngé de pneumocoques résistants dans les crèches des Alpes-Maritimes.