[Applications of stable isotopes in biomedical sciences].
The employment of stable isotopes technology allows to perform a wide range of studies in vivo avoiding the utilisation of radioactive isotopes. As stable isotopes naturally occur in nature, the technique detects the enrichment in breath air of the tracer administered. Stable isotopes technology is increasingly being used in biomedical investigation due to the security of its use and the development and availability of new substrates. Breath tests such 13C-urea in the detection of Helicobacter pylori and 13C-octanoic acid for gastric emptying are the most important clinical applications.
González
A
A
Servicio de Bioquímica, Facultad de Medicina, Universidad de Navarra.
Monreal
I
I
Mugueta
C
C
Parra
D
D
Fernández
F J
FJ
Riaño
M
M
D000596:Amino Acids; D001944:Breath Tests; D002210:Caprylates; D002247:Carbon Isotopes / Q000032:analysis; D019937:Diagnostic Techniques and Procedures; D008401:Gas Chromatography-Mass Spectrometry; D005746:Gastric Emptying; D005767:Gastrointestinal Diseases / Q000175:diagnosis; D016481:Helicobacter Infections / Q000175:diagnosis; D016480:Helicobacter pylori; D006801:Humans; D007553:Isotope Labeling; D007554:Isotopes / Q000032:analysis*; D050356:Lipid Metabolism; D008055:Lipids; D011506:Proteins / Q000378:metabolism; D012449:Safety; D014508:Urea
D000596:Amino Acids; D002210:Caprylates; D002247:Carbon Isotopes; D007554:Isotopes; D008055:Lipids; D011506:Proteins; D014508:Urea; C031492:octanoic acid
Aplicación de los isótopos estables en ciencias biomédicas.