[Complications of cordocentesis associated with fetal therapy].
OBJECTIVE
To evaluate the technical and obstetrical risk factors of percutaneous umbilical blood sampling (PUBS) when associated with simultaneous fetal therapy.


METHODS
Retrospective study. One thousand PUBS have been performed in our department between 1984 and 1992. One hundred and forty one of them were done with another invasive fetal procedure. Technical and obstetrical circumstances were related to pregnancy follow-up and complications.


RESULTS
Pregnancy complication rate increased when PUBS was associated with another invasive procedure (fetal losses: 12.9%, premature rupture of membranes (PROM): 11.6%). No chorioamnionitis nor perinatal infection was observed. As expected, previous fetal status was a main risk factor. Significant relationships have been found between fetal loss risk and therapy procedures such as amnioinfusion and severe IUGR and as well as abnormal post operative fetal tracing. The duration of cord bleeding after needle retrieval was the single risk factor pointed out for PROM.


CONCLUSIONS
The study of the predictors of fetal complications is necessary to separate the genuine risk of previous fetal status and the risk of the invasive procedure itself.
Maternité, Hôtel-Dieu, Clermont-Ferrand.
J A
JA
Bournazeau
B
B
Aublet-Cuvellier
J
J
Raiga
B
B
Jacquetin
D
D
Lémery
D017218:Cordocentesis / Q000009:adverse effects*; D005260:Female; D005313:Fetal Death; D005315:Fetal Diseases / Q000628:therapy*; D005322:Premature Rupture of Fetal Membranes; D006801:Humans; D011247:Pregnancy; D012189:Retrospective Studies; D012307:Risk Factors
Les complications des cordocentèses associées à un geste thérapeutique.