Microcirculation and Chagas' disease: hypothesis and recent results.
This review focuses on studies that support the microvascular hypothesis, as well as on immunological and neurogenic mechanisms, and the role of the parasite itself, to explain further the pathology and clinical course of myocardial involvement in chagasic cardiomyopathy. The salient features of coronary microcirculation and Chagas' disease are discussed.
Ramos
S G
SG
Department of Pathology, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Brazil. sgramos@fmrp.usp.br
Rossi
M A
MA
D000818:Animals; D002598:Chagas Cardiomyopathy / Q000503:physiopathology*; D004285:Dogs; D006801:Humans; D051379:Mice; D008833:Microcirculation / Q000503:physiopathology; D051381:Rats