[The evaluation of hemostatic disorders in patients with systemic lupus erythematosus].
OBJECTIVE
Assessment of hemostasis in SLE patients.


METHODS
We studied different coagulation parameters such as activated partial thromboplastin time (APTT), thrombin time (TT), prothrombin time (PT), activated clotting time (ACT); platelet aggregation (spontaneous and induced), fibrinolytic activity, concentration of fibrinogen, fibrinogen degradation products (FDP) and serotonin.


RESULTS
Coagulation abnormalities were found with prevalence of hypercoagulation in APTT and TT tests. Fibrinolysis was inhibited. Levels of serotonin, FDP and spontaneous aggregation activity significantly increased.


CONCLUSIONS
The above changes were typical for lingering DIC syndrome.
A V
AV
Arshinov
V A
VA
Lapin
Iu A
IuA
Raĭt
D000328:Adult; D001778:Blood Coagulation Disorders / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D001780:Blood Coagulation Tests / Q000706:statistics & numerical data; D005260:Female; D006487:Hemostasis; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D008297:Male
Otsenka narusheniĭ gemostaza u bol'nykh sistemnoĭ krasnoĭ volchankoĭ.