Cardiopulmonary bypass on a patient with malaria.
There are special considerations when performing cardiopulmonary bypass (CPB) on a patient with malaria. A 70-year-old female with a recent history of severe aortic stenosis was scheduled to undergo elective aortic valve replacement. One week prior to surgery, the patient developed shaking chills and fever, with a positive malaria smear. An extensive literature search was undertaken to determine the effect of CPB on a patient with active malaria, but no prior reference was found. One major concern was the lysis of red blood cells while on bypass. The surgery was performed uneventfully, following 2 weeks of treatment with primaquine phosphate.
Coley
T J
TJ
Baxter Perfusion Services, Harrisburg, Pennsylvania, USA. TJColey@aol.com
Hart
J C
JC
D000368:Aged; D000962:Antimalarials / Q000008:administration & dosage; D002315:Cardiopulmonary Bypass; D005260:Female; D006331:Heart Diseases / Q000150:complications* / Q000601:surgery*; D006801:Humans; D016778:Malaria, Falciparum / Q000150:complications*; D011183:Postoperative Complications / Q000517:prevention & control; D011319:Primaquine / Q000008:administration & dosage
D000962:Antimalarials; D011319:Primaquine