Small-cell carcinoma of the ovary of the hypercalcemic type in an 8-year-old girl.
Tumors of the ovary in girls represent about 80% of pediatric genital tumors; approximately 30% of these tumors are malignant. The risk of malignancy increases with decreasing age. The most frequent finding is a teratoma; other tumors are rare. Small-cell carcinoma (SCCO) of the ovary is extremely rare, occurring mostly in young women. We present an 8-year-old girl with a SCCO of the hypercalcemic type. The findings and treatment are discussed with emphasis on the poor prognosis in these patients, even in stage 1 disease. The current literature is reviewed.
Department of Pediatric Hematology and Oncology, WW University of Münster, Germany.
J
J
Schleef
A
A
Wagner
R
R
Kleta
K
K
Schaarschmidt
B
B
Dockhorn-Dworniczak
G
G
Willital
H
H
Jürgens
D015746:Abdominal Pain / Q000209:etiology; D017677:Age Distribution; D001706:Biopsy; D018288:Carcinoma, Small Cell / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D002648:Child; D003937:Diagnosis, Differential; D005221:Fatigue / Q000209:etiology; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D006934:Hypercalcemia / Q000097:blood / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D010051:Ovarian Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D010052:Ovariectomy; D011379:Prognosis; D014057:Tomography, X-Ray Computed