[Detection of Epstein-Barr virus in Malt type gastric malignant lymphoma using in situ hybridization].
The aim of our study was to look for Epstein Barr virus (EBV) genome by in situ hybridization in 23 MALT gastric lymphomas. 15 cases were of low grade, and 8 were of high grade malignancy. We obtained a positive result in 3 cases (13%) of low grade lymphomas. EBV was present in few centrocyte-like and centroblastic cells. Literature review shows an EBV infection rate varying between 8 and 12% with variables results which don't allow strong and reliable conclusion. An etiopathogenic role for EBV in Malt gastric lymphoma remain yet hypothetic.
Service d'Anatomie Pathologique, Hôpital Militaire, Tunis, Tunisie.
A
A
Ben Rejeb
N K
NK
Kchir
B
B
Laâbidi
R
R
Bouali
N
N
Ebdelli
F
F
Khediri
D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D017403:In Situ Hybridization; D018442:Lymphoma, B-Cell, Marginal Zone / Q000821:virology*; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000821:virology*
Recherche du virus d'Epstein Barr dans les lymphomes malins de type Malt gastriques par hybridation in situ.