[Normal tissue radiation toxicity in radiotherapy of localized prostatic cancer].
Radical radiotherapy of prostate cancer has to balance tumour control against the risk of radiation injury of normal tissue. The normal tissue toxicity is the main dose-limiting factor, and consequently a limiting factor of the curative potential of prostate cancer by irradiation. The SOMA scale is a new toxicity scoring system that registers late side effects from the most important anatomical sites. The SOMA scale is internationally approved and facilitates a standardised evaluation of radiation toxicity. The scoring system is based on four main components: subjective, objective, management and analysis. The SOMA scoring system was applied to a group of 21 patients from Ullevaal Hospital who were given intentionally curative radiation therapy for localised prostate cancer. The SOMA scale scoring system appears to be a valuable tool in the evaluation of normal tissue toxicity. It may contribute to a new standard in quality assurance of radiation therapy of prostate cancer.
Bakken
A M
AM
Urologisk avdeling, Ullevål sykehus, Oslo.
Ogreid
P
P
Iversen
J
J
Langberg
C W
CW
D000368:Aged; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000276:immunology / Q000473:pathology / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000175:diagnosis / Q000209:etiology*; D011879:Radiotherapy Dosage; D012007:Rectum / Q000528:radiation effects; D011795:Surveys and Questionnaires; D014521:Urethra / Q000528:radiation effects; D001743:Urinary Bladder / Q000528:radiation effects
Normalvevstoksisitet ved strålebehandling av lokalisert prostatacancer.