Transient increase of intracellular cAMP by heat shock initiates the suppression of MT1-MMP production in tumor cells.
Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Japan.
Y
Y
Sawaji
T
T
Sato
M
M
Seiki
A
A
Ito
D002478:Cells, Cultured; D002584:Cervix Uteri / Q000166:cytology / Q000378:metabolism*; D000242:Cyclic AMP / Q000378:metabolism*; D004792:Enzyme Precursors / Q000235:genetics; D005260:Female; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D005354:Fibrosarcoma; D018093:Gelatinases / Q000235:genetics; D005786:Gene Expression Regulation; D006358:Hot Temperature; D006801:Humans; D007700:Kinetics; D053504:Matrix Metalloproteinases, Membrane-Associated; D008666:Metalloendopeptidases / Q000235:genetics*; D013997:Time Factors; D019716:Tissue Inhibitor of Metalloproteinase-2 / Q000235:genetics*; D014407:Tumor Cells, Cultured
D004792:Enzyme Precursors; D019716:Tissue Inhibitor of Metalloproteinase-2; D000242:Cyclic AMP; D018093:Gelatinases; D053504:Matrix Metalloproteinases, Membrane-Associated; D008666:Metalloendopeptidases; C069860:progelatinase