Referred pain to the ipsilateral forehead and orbit: An unusual phenomenon during bronchial artery embolization.
OBJECTIVE
We report an unusual pattern of referred pain to the ipsilateral forehead and orbit observed during bronchial artery embolization (BAE) for massive hemoptysis due to pulmonary tuberculosis (TB) and postulate possible neural mechanisms for its occurrence.


METHODS
Seven men, from a series of 194 patients (171 men, 23 women) undergoing BAE (right bronchial artery 4, left 3) with gelatin sponge for control of massive hemoptysis due to pulmonary TB form the subject of this report.


RESULTS
Embolization was successful in achieving control of hemoptysis in these patients and there were no complications following the embolization. Transient, moderately severe, ipsilateral supraorbital and/or retroorbital pain occurred only during the injection of the gelatin sponge contrast mixture into the bronchial artery. The pain did not occur during the injection of heparinized saline or ionic contrast medium.


CONCLUSIONS
Referred pain during BAE is an unusual phenomenon. Acute vessel distension triggering visceral sensations is probably the causative mechanism. Sympathetic afferents from the bronchi coursing through the posterior pulmonary plexus eventually pass to the trigeminal ganglion via the carotid sympathetic chain. The ophthalmic and maxillary divisions of the trigeminal nerve then mediate pain sensation to the ipsilateral forehead and orbit. Similarly, parasympathetic afferents from the pulmonary plexus crossing the nucleus of the spinal tract of the trigeminal nerve may be responsible for interexchange of impulses to the neurons in this nucleus. Sensory fibers of the ophthalmic and maxillary nerves relaying in this nucleus are then involved in this pain being referred to the forehead and orbit.
Department of Radiology, King Edward Memorial Hospital, Bombay 400 012, India.
R
R
Ramakantan
M
M
Ketkar
K
K
Maddali
H
H
Deshmukh
D000328:Adult; D000368:Aged; D000792:Angiography; D001981:Bronchial Arteries / Q000000981:diagnostic imaging; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D005157:Facial Pain / Q000209:etiology*; D005260:Female; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use; D006469:Hemoptysis / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009916:Orbital Diseases / Q000209:etiology*; D012189:Retrospective Studies; D014397:Tuberculosis, Pulmonary / Q000150:complications
D006490:Hemostatics