Pendelluft flow in symmetric airway bifurcations.
We propose a mathematical model for pendelluft flow in a single airway bifurcation. The model is motivated by an apparatus used in an experimental study of the pendelluft by Ultman et al. (1988). We derive differential equations governing the fluid flow, which directly connect physiological parameters to the variables determining the pendelluft; this approach allows us to include nonlinearity in the model. If nonlinearity is neglected, our model is identical to the R-I-C circuits used by previous investigators. If nonlinearity is retained, we show that pendelluft can occur even in perfectly symmetric airway bifurcations. For the specific apparatus used in the experiments of High et al. (1991), we demonstrate that two qualitatively different pendelluft flows can occur in the system.
Feng
Z C
ZC
Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge 02139, USA.
Poon
C S
CS
D000403:Airway Resistance / Q000502:physiology*; D001980:Bronchi / Q000502:physiology*; D004548:Elasticity; D016014:Linear Models; D008954:Models, Biological; D017711:Nonlinear Dynamics; D009716:Numerical Analysis, Computer-Assisted; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012126:Respiratory Dead Space / Q000502:physiology*; D012212:Rheology