Attenuation of tolerance to opioid-induced antinociception by idazoxan and other I2-ligands.
Boronat
M A
MA
Institute of Neurobiology Ramón y Cajal/CSIC, Department of Biology, University of the Balearic Islands, Palma de Mallorca, Spain.
Olmos
G
G
García-Sevilla
J A
JA
D000818:Animals; D004361:Drug Tolerance / Q000502:physiology*; D019329:Idazoxan / Q000031:analogs & derivatives* / Q000494:pharmacology*; D007093:Imidazoles / Q000494:pharmacology*; D054755:Imidazoline Receptors; D008024:Ligands; D008297:Male; D009020:Morphine / Q000494:pharmacology*; D010146:Pain / Q000503:physiopathology*; D010423:Pentazocine / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D011955:Receptors, Drug / Q000502:physiology*
D007093:Imidazoles; D054755:Imidazoline Receptors; D008024:Ligands; D011955:Receptors, Drug; D009020:Morphine; D010423:Pentazocine; D019329:Idazoxan