Enzymatic resolution of amino acids via ester hydrolysis.
The present review outlines recent examples of enzyme-based resolution procedures for amino acids via the hydrolysis of their esters. The resolutions have been achieved by using proteases (alpha-chymotrypsin, subtilisin and other microbial proteases, and sulfhydryl proteases of plant origin) and lipases. Relevant work utilizing yeast and other microbial cells is also included.
Miyazawa
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Department of Chemistry, Faculty of Science, Konan University, Kobe, Japan.
D000596:Amino Acids / Q000378:metabolism*; D002918:Chymotrypsin / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism*; D004952:Esters / Q000378:metabolism*; D006868:Hydrolysis; D008049:Lipase / Q000378:metabolism; D010944:Plants / Q000201:enzymology; D012441:Saccharomyces cerevisiae / Q000201:enzymology; D013381:Subtilisins / Q000378:metabolism
D000596:Amino Acids; D004952:Esters; D008049:Lipase; D010450:Endopeptidases; D013381:Subtilisins; D002918:Chymotrypsin