Long-term prognosis of Legg-Calvé-Perthes disease: a meta-analysis.
In the literature, long-term prognosis of Legg-Calvé-Perthes disease (LCPD) means prognosis for secondary osteoarthritis of the hip joint or leg-length inequality and its consequences. Most studies show results after conservative treatment. The long-term natural history of LCPD is not known. In spite of deformity, most patients do well in early adulthood. Radiographic and clinical osteoarthritis is increased in 20-year to 40-year follow-ups and degenerative joint disease develops in the majority of patients by the sixth or seventh decade of life. The reported average shortening of the affected leg has usually been 1 to 1.5 cm. There are no thorough long-term reports on low back pain after LCPD. The only evidence-based factors that are of prognostic importance in the long-term are age of the patient at the onset of the disease and shape of the femoral head at skeletal maturity.
Orton Orthopaedic Hospital, Helsinki, Finland.
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D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D018450:Disease Progression; D005260:Female; D006801:Humans; D007223:Infant; D007870:Leg Length Inequality / Q000453:epidemiology / Q000209:etiology*; D007873:Legg-Calve-Perthes Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D015207:Osteoarthritis, Hip / Q000453:epidemiology / Q000209:etiology*; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index; D013997:Time Factors