Recurrence of IgA nephropathy after renal transplantation.
With time recurrence of IgA nephropathy in renal allografts may be found in most, if not all patients. However, at the present graft loss due to recurrent IgA nephropathy appears to be of limited importance as compared to other causes. No definite risk factors for recurrent disease and/or graft failure have been identified yet. Although recurrence rates appear to be higher in allografts from living related donors, graft loss rates due to IgA nephropathy are not significantly different. More important, sporadic cases of IgA nephropathy should be excluded in all living related donors.
Department of Nephrology, Leiden University Medical Centre, The Netherlands.
P J
PJ
van der Boog
J W
JW
de Fijter
J A
JA
Bruijn
L A
LA
van Es
D001706:Biopsy; D005922:Glomerulonephritis, IGA / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D019520:Living Donors; D012008:Recurrence; D012307:Risk Factors; D014184:Transplantation, Homologous; D016896:Treatment Outcome