Tissue engineering of bone in the craniofacial complex.
Tissue engineered therapies to regenerate bone in the craniofacial complex will probably include combinations of BMP-like molecules, a BMP-responsive set of cells (both endogenous and exogenous), and packaging in a surgically convenient format. In this report we have described our work with OPCs, BMP, and polymer: components suitable for tissue engineering.
Hollinger
J O
JO
Division of Plastic and Reconstructive Surgery, Oregon Health Sciences University, Portland 97201-3098, USA. hollinge@ohsu.edu
Winn
S R
SR
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000008:administration & dosage / Q000494:pharmacology; D001861:Bone Regeneration / Q000187:drug effects; D002460:Cell Line; D004337:Drug Carriers; D005147:Facial Bones / Q000502:physiology*; D006801:Humans; D010006:Osteoblasts / Q000166:cytology; D011108:Polymers; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000494:pharmacology; D012886:Skull / Q000502:physiology*
D019485:Bone Morphogenetic Proteins; D004337:Drug Carriers; D011108:Polymers; D011994:Recombinant Proteins