[Cyclophosphamide-induced interstitial pneumopathy. Course data of bronchoalveolar lavage apropos of a case and review of the literature].
A patient treated with cyclophosphamide for breast cancer developed functional and clinicoradiological signs of sub-acute diffuse interstitial pneumopathy. Bronchoalveolar lavage revealed lymphocyte alveolitis. Differential diagnoses were excluded and the course was favorable after cyclophosphamide withdrawal. The bronchoalveolar lavage results obtained initially and at follow-up and two previous lavages reported in the literature demonstrate the importance of this examination in the diagnosis of drug-induced pneumopathy.
Service de Pneumologie, Hôpital d'Instruction des Armées Laveran, Marseille Armées.
A
A
Cuguillière
H
H
Bérard
G
G
N'Guyen
J
J
Miltgen
G
G
Martet
J
J
Eskandari
D
D
Bonnet
D000328:Adult; D018906:Antineoplastic Agents, Alkylating / Q000009:adverse effects*; D018893:Bronchoalveolar Lavage; D003520:Cyclophosphamide / Q000009:adverse effects*; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced* / Q000175:diagnosis / Q000000981:diagnostic imaging; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed
D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide
Pneumopathie interstitielle liée au cyclophosphamide. Données évolutives du lavage broncho-alvéolaire à propos d'un cas et revue de la littérature.