[Oligodendroglioma: a pathological and clinical study of 15 cases].
Oligodendrogliomas account for 4-5% of primary central nervous system tumours with a slow and infiltrative growth. We report the clinical and pathological findings of 15 cases of oligodendrogliomas. Eight patients were males and 7 were females. The ages ranged between 17 and 66 years, with a mean of 39.73 years. The symptoms reflected the growth and topography of the tumours; migraine (60%) and seizures (60%) were the most frequent symptoms. Frontal (n = 6), parietal (n = 2), temporal (n = 1) and occipital (n = 1) lobes were affected. Five patients undergone total resection of the tumor and 10 were submitted to partial resection, from which 3 received adjuvant radiotherapy, 1 adjuvant chemotherapy and 1 chemotherapy and radiotherapy. The overall recurrence rate was 60% for a 32 month follow up. Five recurrences were observed in patients submitted only to the surgical treatment and 4 in which adjuvant radio or chemotherapy were performed. These results are similar with the literature and may contribute to further understanding the biological behavior of these rare tumours.
Reis Filho
J S
JS
Serviço de Anatomia Patológica (SAP), Hospital de Clínicas (HC), Universidade Federal do Paraná (UFPR), Curitiba, PR, Brasil. jsreis@hotmail.com ou neuropat@hc.ufpr.br
Netto
M R
MR
Sluminsky
B G
BG
Dellé
L A
LA
Antoniuk
A
A
Ramina
R
R
Torres
L F
LF
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D001932:Brain Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D001938:Brazil / Q000453:epidemiology; D016543:Central Nervous System Neoplasms / Q000453:epidemiology / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009837:Oligodendroglioma / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy
Oligodendrogliomas. Estudo anatomopatológico e clínico de 15 casos.