[The evaluation of a new immunoenzyme analysis for the detection of Helicobacter pylori infection in stool samples].
BACKGROUND
Detection of bacterial antigen in stool specimens (HpSAT) is a new promising tool for diagnosing Helicobacter pylori infection.


OBJECTIVE
To evaluate diagnostic accuracy of HpSAT in the diagnosis of Helicobacter pylori infection.


METHODS
We evaluate the presence of Helicobacter pylori infection by the rapid urease test and the 13C-urea breath test in endoscopic biopsies. Patients who were positive for both tests were considered to have Helicobacter pylori infection. Patients negative for both tests were considered free of infection. The presence of Helicobacter pylori infection was also determined in stool specimens by means of HpSAT.


RESULTS
The sensitivity of HpSAT was 92.8%, the specificity 92.3%, the positive predictive value 98.1% and the negative predictive value 75%.


CONCLUSIONS
HpSAT is a reliable tool for diagnosing Helicobacter pylori infection.
Servicio de Medicina Interna, Corporació Sanitària del Parc Taulí, Sabadell, Barcelona. xcalvet@cspt.es
X
X
Calvet
F
F
Feu
M
M
Forné
A
A
Montserrat
J I
JI
Elizalde
J M
JM
Viver
N
N
Gali
J
J
Domínguez
D000328:Adult; D000368:Aged; D000942:Antigens, Bacterial / Q000032:analysis*; D005243:Feces / Q000737:chemistry*; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012680:Sensitivity and Specificity
D000942:Antigens, Bacterial
Evaluación de un nuevo enzimoinmunoanálisis para la detección de la infección por Helicobacter pylori en muestras fecales.