Study of saliva secretion and the salivary fluoride concentration of the human minor labial glands by a new method.
Unstimulated and stimulated flow rate from minor lower labial glands and the fluoride concentration of resting whole and labial saliva were measured over 15 min using a novel method avoiding eversion of the lips. Resting salivary flow rate was measured as 1.09+/-0.44 microl/min/cm2 and stimulated flow rate as 3.13+/-1.05 microl/min/cm2. Secretion rates were significantly (p<0.001) increased during periods of continuous speaking. The increase in secretion elicited by labial movements and speaking may result from mechanical stimulation and/or activity of myoepithelial cells. Fluoride concentrations in resting whole saliva and in unstimulated minor labial gland saliva were 0.066+/-0.048 and 0.181+/-0.073 parts/10(6), respectively. The secretory capacity of the minor labial glands and the high F concentration in their secretions suggests a significant contribution to the F content of whole saliva. Our non-invasive method permits collection from the minor labial glands of a volume large enough for chemical analysis. It should prove useful for studying the effects of different secretory stimuli.
Department of Oral Biology, Faculty of Dentistry, Semmelweis University of Medicine, Budapest, Hungary.
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Boros
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Keszler
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Zelles
D000328:Adult; D004847:Epithelial Cells / Q000502:physiology; D005260:Female; D005459:Fluorides / Q000032:analysis*; D006801:Humans; D008046:Lip / Q000033:anatomy & histology* / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009068:Movement; D012463:Saliva / Q000737:chemistry / Q000378:metabolism*; D012470:Salivary Glands, Minor / Q000378:metabolism*; D012636:Secretory Rate; D013060:Speech / Q000502:physiology
D005459:Fluorides