[Population study of antibodies to some potential pathogens of spondyloarthopathies: the study of the Chukotka population].
The paper presents the results of the study of specific immune response stimulated by some enterobacteria in populations with high incidence of HLA-B27. A, M and G antibodies to Yersinia, Clebsiella, Salmonella and Campilobacter were studied on 292 plasma samples. The levels of the antibodies varied with anthropological parameters of the examinees (gender, age, nationality). The presence of the gene HLA-B27 in the genotype levels gender dimorphism of the specific humoral immune response. This may be of importance in pathogenesis of spondyloarthropathies which occur more frequently in men.
Guseva
I A
IA
Uksila
J
J
Erdes
Sh
Sh
Toivanen
R
R
Benevolenskaia
L I
LI
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000276:immunology; D002391:Catchment Area, Health; D002648:Child; D004756:Enterobacteriaceae Infections / Q000276:immunology*; D005260:Female; D006680:HLA Antigens / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D012426:Russia / Q000453:epidemiology; D013167:Spondylitis, Ankylosing / Q000208:ethnology / Q000276:immunology*
D000907:Antibodies, Bacterial; D006680:HLA Antigens; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Populiatsionnoe issledovanie antitel k nekotorym potentsial'nym agentam spondiloartropatiĭ: izuchenie populiatsiĭ Chukotki.