Serum homocysteine increases after therapy with fenofibrate or bezafibrate.
A 44% and 17.5% increase of homocysteine occurred in patients treated either with fenofibrate or bezafibrate. The increase was not explained by changes in vitamin concentrations but may be related to renal function.
Dierkes
J
J
Westphal
S
S
Luley
C
C
D000328:Adult; D001629:Bezafibrate / Q000627:therapeutic use*; D002851:Chromatography, High Pressure Liquid; D011345:Fenofibrate / Q000627:therapeutic use*; D005492:Folic Acid / Q000097:blood; D006397:Hematinics / Q000097:blood; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D020138:Hyperhomocysteinemia / Q000139:chemically induced*; D015228:Hypertriglyceridemia / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011736:Pyridoxine / Q000097:blood; D014805:Vitamin B 12 / Q000097:blood
D006397:Hematinics; D000960:Hypolipidemic Agents; D006710:Homocysteine; D005492:Folic Acid; D011736:Pyridoxine; D014805:Vitamin B 12; D011345:Fenofibrate; D001629:Bezafibrate