On the analogy between forskolin and D-glucose.
2-O-Acetyl-D-glucose was synthesized in order to evaluate the influence of an acyl group on the binding with the glucose carrier protein (GluT); as its affinity neighbours that of glucose itself, the glucose-forskolin analogy appears to be coincidental and several explanations are proposed.
Abbadi
M
M
Laboratoire d'Etudes Dynamiques et Structurales de la Sélectivité UMR CNRS 5616, Université de Grenoble, France.
Morin
C
C
D017667:Adipocytes / Q000187:drug effects; D000495:Allosteric Site; D000818:Animals; D005576:Colforsin / Q000737:chemistry* / Q000378:metabolism; D005947:Glucose / Q000031:analogs & derivatives / Q000737:chemistry* / Q000378:metabolism; D007700:Kinetics; D051381:Rats
D005576:Colforsin; D005947:Glucose