Study of saliva secretion and the salivary fluoride concentration of the human minor labial glands by a new method.
Unstimulated and stimulated flow rate from minor lower labial glands and the fluoride concentration of resting whole and labial saliva were measured over 15 min using a novel method avoiding eversion of the lips. Resting salivary flow rate was measured as 1.09+/-0.44 microl/min/cm2 and stimulated flow rate as 3.13+/-1.05 microl/min/cm2. Secretion rates were significantly (p<0.001) increased during periods of continuous speaking. The increase in secretion elicited by labial movements and speaking may result from mechanical stimulation and/or activity of myoepithelial cells. Fluoride concentrations in resting whole saliva and in unstimulated minor labial gland saliva were 0.066+/-0.048 and 0.181+/-0.073 parts/10(6), respectively. The secretory capacity of the minor labial glands and the high F concentration in their secretions suggests a significant contribution to the F content of whole saliva. Our non-invasive method permits collection from the minor labial glands of a volume large enough for chemical analysis. It should prove useful for studying the effects of different secretory stimuli.
Boros
I
I
Department of Oral Biology, Faculty of Dentistry, Semmelweis University of Medicine, Budapest, Hungary.
Keszler
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P
Zelles
T
T
D000328:Adult; D004847:Epithelial Cells / Q000502:physiology; D005260:Female; D005459:Fluorides / Q000032:analysis*; D006801:Humans; D008046:Lip / Q000033:anatomy & histology* / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009068:Movement; D012463:Saliva / Q000737:chemistry / Q000378:metabolism*; D012470:Salivary Glands, Minor / Q000378:metabolism*; D012636:Secretory Rate; D013060:Speech / Q000502:physiology
D005459:Fluorides