Pulmonary stenosis and severe biventricular dysfunction: improvement following percutaneous valvuloplasty.
A 15-year-old boy with severe pulmonary stenosis associated with severe right and left ventricular systolic dysfunction is reported. After successful percutaneous pulmonary valvuloplasty, there was an initial and early improvement in right ventricular (RV) function, followed by a delayed and more gradual improvement in left ventricular (LV) function. At long-term follow up, both RV and LV systolic functions were nearly normalized. Several mechanisms may be implicated, including ventricular interdependence, geometric factors, altered compliance and intrinsic alteration in the LV muscle. A delayed, but sustained, improvement in LV systolic function following relief of RV pressure overload suggests that the latter mechanism must have played an important role in the genesis of the LV dysfunction. Pulmonary stenosis associated with severe biventricular dysfunction may be treated primarily by percutaneous pulmonary balloon valvuloplasty with near-total recovery of the ventricular function.
King Faisal Specialist Hospital and Research Center, Department of Cardiovascular Diseases, Riyadh, Saudi Arabia.
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AA
Patel
L
L
Hatle
L
L
Mimish
D000293:Adolescent; D006328:Cardiac Catheterization; D002404:Catheterization; D006801:Humans; D008297:Male; D011666:Pulmonary Valve Stenosis / Q000150:complications* / Q000503:physiopathology; D018487:Ventricular Dysfunction, Left / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D018497:Ventricular Dysfunction, Right / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*