Evidence for medullary projections of the intercostal nerve-elicited inspiratory termination.
This study hypothesized that the ICN-elicited inspiratory termination reflex required synaptic activation in two distinct regions of the ventral respiratory group (VRG): (1) transitional (tVRG), and (2) pre-Bötzinger complex (pre-BötC). Data from adult cats indicate that axons of passage associated with the ICN-elicited termination reflex traverse tVRG, but that relevant synaptic processing does not occur in this region. Furthermore, data indicate that neither synaptic nor axonal transmission within the pre-BötC is required for the SLN- or ICN-elicited termination reflex.
Anderson
M K
MK
Department of Physiology, University of Kentucky, MS 515 Chandler Medical Center, Lexington, KY 40536-0298, USA.
Speck
D F
DF
D000704:Analysis of Variance; D000818:Animals; D001369:Axons / Q000502:physiology; D002415:Cats; D007367:Intercostal Nerves / Q000502:physiology*; D008526:Medulla Oblongata / Q000502:physiology*; D009411:Nerve Endings / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology; D012018:Reflex / Q000502:physiology*; D012119:Respiration; D009435:Synaptic Transmission / Q000502:physiology