Combined sentinel lymph-node mapping and bone-marrow micrometastatic analysis for improved staging in breast cancer.
In a prospective study of 29 patients with clinically node-negative breast cancer, sampling of rib marrow was superior to sampling of iliac-crest marrow for detection of micrometastases. Combination of marrow micrometastatic analysis with sentinel lymph-node mapping may improve accuracy of staging in breast cancer.
Relihan
N
N
McGreal
G
G
Kelly
J
J
Ryan
D
D
O'Sullivan
G C
GC
Redmond
H P
HP
D001365:Axilla; D019046:Bone Marrow Neoplasms / Q000473:pathology / Q000556:secondary*; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007085:Ilium; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000175:diagnosis; D009367:Neoplasm Staging / Q000379:methods*; D011446:Prospective Studies; D012272:Ribs / Q000473:pathology