HSP70 induction may explain the long-lasting resistance to heat of Drosophila melanogaster having lived in hypergravity.
In this study, we showed that in flies kept for 2 weeks at 1 (terrestrial gravity), 3 or 5 x g (hypergravity, HG) before transfer to 1 x g, resistance to heat remained higher in HG flies for several weeks after the transfer. The measurement of heat shock protein 70 (hsp70) indicated no induction of the protein in HG, but the study revealed that flies living in HG expressed more hsp70 only after being submitted to severe stress. The higher induction of hsp70 may explain the higher thermotolerance of these HG-treated young flies. Finally, an unknown protein was observed only in females. This protein may belong to a class of higher molecular weight hsp (hsp110), which have not previously been observed in Drosophila.
Department of Ecology, Evolution, and Behavior, University of Minnesota, St. Paul 55108, USA. minoi002@tc.umn.edu
N
N
Minois
M J
MJ
Guinaudy
F
F
Payre
E
E
Le Bourg
D000367:Age Factors; D000375:Aging; D000818:Animals; D004331:Drosophila melanogaster / Q000502:physiology*; D005260:Female; D005786:Gene Expression Regulation; D050957:HSP110 Heat-Shock Proteins; D018840:HSP70 Heat-Shock Proteins / Q000096:biosynthesis* / Q000235:genetics; D018869:Heat-Shock Response / Q000235:genetics; D006358:Hot Temperature; D018471:Hypergravity; D008136:Longevity; D008297:Male; D008970:Molecular Weight; D012737:Sex Factors; D013997:Time Factors
D050957:HSP110 Heat-Shock Proteins; D018840:HSP70 Heat-Shock Proteins