Chronic inflammatory demyelinating polyneuropathy with multiple hypertrophic nerves in intracranial, and intra- and extra-spinal segments.
Hypertrophic nerves have occasionally been seen in chronic inflammatory demyelinating polyneuropathy (CIDP), but most are in the cauda equina. We report a case with CIDP in whom magnetic resonance imaging (MRI) with gadolinium diethylene triamine penta-acetic acid (Gd-DTPA) enhancement demonstrated hypertrophy of various peripheral nerves including multiple cranial nerves. Interestingly, none showed neurological signs corresponding to the lesions, except for clinical signs consistent with CIDP. MRI can be useful for the detection of silent, but abnormal nerve involvement in CIDP.
Department of Neurology, Hokkaido University School of Medicine, Sapporo.
M
M
Niino
S
S
Tsuji
K
K
Tashiro
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003391:Cranial Nerves / Q000187:drug effects / Q000473:pathology*; D003711:Demyelinating Diseases / Q000150:complications* / Q000175:diagnosis; D019786:Gadolinium DTPA; D006801:Humans; D006984:Hypertrophy; D008279:Magnetic Resonance Imaging; D008297:Male; D010523:Peripheral Nervous System Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D013126:Spinal Nerve Roots / Q000187:drug effects / Q000473:pathology*
D000893:Anti-Inflammatory Agents; D011239:Prednisolone; D019786:Gadolinium DTPA