The 9-kDa N-terminal propeptide domain of MT1-MMP is required for the activation of progelatinase A.
Department of Medicine, School of Medicine and Dentistry, State University of New York at Stony Brook 11794, USA.
J
J
Cao
M
M
Drews
H M
HM
Lee
C
C
Conner
W F
WF
Bahou
S
S
Zucker
D000595:Amino Acid Sequence; D000818:Animals; D019556:COS Cells; D002462:Cell Membrane / Q000378:metabolism; D016384:Consensus Sequence; D004789:Enzyme Activation; D004792:Enzyme Precursors / Q000737:chemistry / Q000378:metabolism*; D018093:Gelatinases / Q000378:metabolism*; D053504:Matrix Metalloproteinases, Membrane-Associated; D008666:Metalloendopeptidases / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D008970:Molecular Weight; D016296:Mutagenesis; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D017384:Sequence Deletion; D014162:Transfection
D004792:Enzyme Precursors; D011994:Recombinant Proteins; D018093:Gelatinases; D053504:Matrix Metalloproteinases, Membrane-Associated; D008666:Metalloendopeptidases; C069860:progelatinase