[Rhinoscleroma: a case report].
BACKGROUND
Rhinoscleroma is a rare infectious disease of the upper respiratory tract caused by Klebsiella rhinoscleromatis. The nasal mucosa represents the primary region of occurrence which is most likely a result of respiratory transmission. Without adequate++ treatment, the disease can potentially spread to the rest of the upper and middle respiratory tract within a period of several years. Healing often occurs with extensive scarring and adhesions of the nose, palate and larynx. A life threatening late stage manifestation includes subglottic stenosis requiring immediate surgical intervention. Medical treatment primarily consists of a long-term course of antibiotics. Ciprofloxacin (Fluoroquinolon) has proved to be one of the most effective drugs.


METHODS
We report about a 33 year-old Egyptian male, who presented in our department with a 10 year history of a previously, only temporarily successfully treated rhinoscleroma. His main symptoms were nasal obstruction, epistaxis and inspiratory stridor.


RESULTS
We began treatment with Ciprofloxacin over a four week period, which lead to an improvement of his symptoms. The treatment was considered complete after several biopsies and smears were negative for live specimens. We then chose to reduce the scar tissue that was causing obstruction in the larynx and the nose.


CONCLUSIONS
The rhinoscleroma is a rare disease in geographic areas with poor hygiene and can mimic several other infectious and malignant diseases. Treatment should include a long-term antimicrobial therapy and surgical intervention in cases with symptomatic obstruction.
Klinik und Poliklinik für Hals-, Nasen- und Ohrenkranke, Ludwig-Maximilians Universität München.
W J
WJ
Issing
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R
Bodlaj
D000328:Adult; D002939:Ciprofloxacin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004724:Endoscopy; D006801:Humans; D007711:Klebsiella pneumoniae; D008297:Male; D009297:Nasal Mucosa / Q000473:pathology; D015508:Nasal Obstruction / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012226:Rhinoscleroma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery
D002939:Ciprofloxacin
Das Rhinosklerom: Ein Fallbericht.