Multichannel magnetocardiographic measurements with a physical thorax phantom.
Artificial dipolar sources were applied inside a physical thorax phantom to experimentally investigate the accuracy obtainable for non-invasive magnetocardiographic equivalent current dipole localisation. For the measurements, the phantom was filled with saline solution of electrical conductivity 0.21 S m-1. A multichannel cardiomagnetometer was employed to record the magnetic fields generated by seven dipolar sources at distances from 25 mm to 145 mm below the surface of the phantom. The inverse problem was solved using an equivalent current dipole in a homogeneous boundary element torso model. The dipole parameters were determined with a non-linear least squares fitting algorithm. The signal-to-noise ratio (SNR) and the goodness of fit of the calculated localisations were used in assessing the quality of the results. The dependence between the SNR and the goodness of fit was derived, and the results were found to correspond to the model. With SNR between 5 and 10, the average localisation error was found to be 9 +/- 8 mm, while for SNR between 30 and 40 and goodness of fit between 99.5% and 100%, the average error reduced to 3.2 +/- 0.3 mm. The SNR values obtained in this study were also compared with typical clinical values of SNR.
Pesola
K
K
Helsinki University of Technology, Laboratory of Biomedical Engineering, HUT, Finland. katja.pesola@hut.fi
Tenner
U
U
Nenonen
J
J
Endt
P
P
Brauer
H
H
Leder
U
U
Katila
T
T
D002309:Cardiology / Q000295:instrumentation / Q000379:methods*; D055590:Electromagnetic Phenomena / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008953:Models, Anatomic; D012680:Sensitivity and Specificity