Xenotransplantation: the potential and the challenges.
Clinical use of xenotransplants is a potential way to provide care for a population of seriously ill patients and alleviate the demand for human organs. However, xenotransplantation also presents a spectrum of concerns, not only for individual patients but also for the public health, that must be discussed and dealt with in a science-based and public manner. Such discussions should take place on a national level and should include scientists, physicians, and policy makers from all countries in which the clinical use of xenografts is being considered.
Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Bethesda, Md., USA.
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Bloom
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Moulton
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McCoy
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Chapman
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Patterson
D000818:Animals; D003422:Critical Care; D003428:Cross Infection / Q000209:etiology / Q000517:prevention & control; D004992:Ethics, Medical; D006084:Graft Rejection / Q000209:etiology / Q000517:prevention & control; D006291:Health Policy; D006801:Humans; D017053:Infection Control; D011634:Public Health; D013045:Species Specificity; D014183:Transplantation, Heterologous / Q000009:adverse effects / Q000379:methods / Q000451:nursing / Q000639:trends*; D014481:United States