[Ependymomas: Clinical, epidemiological and clinico-pathological findings of 22 cases].
Ependymomas are composed of neoplastic ependymal cells, affecting mainly children and young adults. We report the clinical and pathological findings of 22 cases of ependymomas. Fourteen patients were males and 8 were females. The ages ranged between 1 and 58 years, with a mean of 24.63 years. The symptoms reflected the growth and topography of the tumours; muscle weakness (59.1%), gait disorders (36.3%), sensitive disorders (36.3%), hyperreflexia and intracranial hypertension syndrome were the most frequent symptoms. Ten tumours affected the medulla, 7 the cerebral hemispheres, 2 the cerebral ventricles and 1 brain stem. Seven patients were submitted total resection of the tumor, from which one received adjuvant radiotherapy. 15 other patients were submitted to partial resection; from which 4 received adjuvant radiotherapy, 3 adjuvant chemotherapy and 1 chemotherapy and radiotherapy. The recurrence rate was 18.2%. These results are similar with the literature and may contribute to further understanding the biological behavior of these tumours.
Torres
L F
LF
Serviço de Anatomia Patológica (SAP), Hospital de Clínicas (HC), Universiade Federal do Paraná (UFPR), Curitiba, PR, Brasil. bleggi@hc.ufpr.br e lftorres@uol.com.br
Reis Filho
J S
JS
Netto
M R
MR
Dellé
L A
LA
Sluminsky
B G
BG
Tironi
F A
FA
Antoniuk
A
A
Ramina
R
R
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D001932:Brain Neoplasms / Q000453:epidemiology / Q000473:pathology*; D001938:Brazil / Q000453:epidemiology; D016543:Central Nervous System Neoplasms / Q000453:epidemiology / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D004806:Ependymoma / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D017678:Sex Distribution
Ependimomas. Achados clínicos, epidemiológicos e anatomopatológicos de 22 casos.