Non-antimicrobial and antimicrobial tetracyclines inhibit IL-6 expression in murine osteoblasts.
Kirkwood
K L
KL
Department of Periodontics, State University of New York at Buffalo 14214, USA. klkirk@acsu.buffalo.edu
Golub
L M
LM
Bradford
P G
PG
D016475:3T3 Cells; D000818:Animals; D004318:Doxycycline / Q000494:pharmacology; D005786:Gene Expression Regulation / Q000187:drug effects*; D015850:Interleukin-6 / Q000096:biosynthesis / Q000235:genetics*; D051379:Mice; D010006:Osteoblasts / Q000187:drug effects / Q000276:immunology*; D011480:Protease Inhibitors / Q000494:pharmacology*; D012333:RNA, Messenger / Q000235:genetics; D013329:Structure-Activity Relationship; D013754:Tetracyclines / Q000494:pharmacology*; D014158:Transcription, Genetic / Q000187:drug effects
D015850:Interleukin-6; D011480:Protease Inhibitors; D012333:RNA, Messenger; D013754:Tetracyclines; C117153:tetracycline CMT-8; D004318:Doxycycline