Salivary gland neoplasms with basaloid cell features: report of two cases diagnosed by fine-needle aspiration cytology.
Basal-cell adenoma and basal-cell adenocarcinoma of the salivary gland are rare tumors. Fine-needle aspiration cytology of these tumors, particularly those of basal-cell adenocarcinoma, has rarely been described in the literature. In this report, we describe the clinical, cytomorphologic, histopathologic, and immunohistochemical features of basal-cell adenoma and its malignant counterpart, basal-cell adenocarcinoma, in 2 patients. Fine-needle aspiration specimens from both tumors contained abundant cohesive groups of neoplastic cells. Basaloid cells were prominent in both tumors; however, there were significant cytologic atypia, hyperchromasia, and increased nuclear-to-cytoplasmic ratio in basal-cell adenocarcinoma. Review of the literature and cytomorphologic distinction between both tumors and others are discussed.
Tawfik
O
O
Department of Pathology, Kansas University Medical Center, Kansas City 66160, USA. otawfik@kumc.edu
Tsue
T
T
Pantazis
C
C
Nuckols
D
D
Younes
S
S
Webb
P
P
D000230:Adenocarcinoma / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D000236:Adenoma / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D001707:Biopsy, Needle; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology* / Q000601:surgery