Enzymatic resolution of amino acids via ester hydrolysis.
The present review outlines recent examples of enzyme-based resolution procedures for amino acids via the hydrolysis of their esters. The resolutions have been achieved by using proteases (alpha-chymotrypsin, subtilisin and other microbial proteases, and sulfhydryl proteases of plant origin) and lipases. Relevant work utilizing yeast and other microbial cells is also included.
Department of Chemistry, Faculty of Science, Konan University, Kobe, Japan.
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Miyazawa
D000596:Amino Acids / Q000378:metabolism*; D002918:Chymotrypsin / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism*; D004952:Esters / Q000378:metabolism*; D006868:Hydrolysis; D008049:Lipase / Q000378:metabolism; D010944:Plants / Q000201:enzymology; D012441:Saccharomyces cerevisiae / Q000201:enzymology; D013381:Subtilisins / Q000378:metabolism
D000596:Amino Acids; D004952:Esters; D008049:Lipase; D010450:Endopeptidases; D013381:Subtilisins; D002918:Chymotrypsin