[Persistent Lactobacillus casei subspecies rhamnosus bacteremia in a 14 year old girl with acute myeloid leukemia. A case report].
The present clinical observation is related to a 14-year-old girl suffering from acute myeloid leukemia. The clinical course was complicated by episodes of severe enterocolitis, E. coli- septicemia, pancreatitis and pneumonia. In the course of continued cytostatic and antibiotic treatment a persistent asymptomatic Lactobacillus casei subsp. rhamnosus-bacteremia became detectable by a total of 18 blood cultures. Microbial cultures of the faeces revealed colony-forming unites of this germ in orders of 10(9)/g. Antibiotic eradication attempts according to the resistogram were not successful. The Lactobacillus-bacteremia disappeared only after 13 months when the cytostatic therapy was terminated. An adjuvant influence of the Lactobacillus infection on the outcome of the underlying disease cannot be excluded.
Universitätskinder- und Jugendklinik Rostock.
J
J
Majcher-Peszynska
W
W
Heine
I
I
Richter
G
G
Eggers
C
C
Mohr
D000293:Adolescent; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents / Q000009:adverse effects; D016470:Bacteremia / Q000209:etiology*; D003561:Cytarabine / Q000009:adverse effects; D004359:Drug Therapy, Combination / Q000009:adverse effects; D004761:Enterocolitis, Pseudomembranous / Q000209:etiology*; D005047:Etoposide / Q000009:adverse effects; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007113:Immunity, Innate; D007780:Lacticaseibacillus casei / Q000302:isolation & purification*; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000188:drug therapy; D012008:Recurrence; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D003561:Cytarabine; D005047:Etoposide
Persistierende Lactobacillus casei subspecies rhamnosus-Bakteriämie bei einer 14-jährigen Patientin mit akuter myeloischer Leukämie. Eine Kasuistik.