[A paraneoplastic acrosyndrome].
BACKGROUND
Paraneoplastic digital ischemia is an uncommon complication of metastatic adenocarcinomas.


METHODS
Two years after remission of an uterine adenocarcinoma, the patient developed an acrosyndrome involving all four limbs with digital ischemia. Recurrent carcinoma was evidenced by a very high antinuclear antibody titer. Chemotherapy improved the acrosyndrome.


CONCLUSIONS
Vasomotor disorders which developed in older subjects with no other signs of autoimmune disorders should suggest a neoplastic origin. Icshemia of the fingers would be caused by vasculitis. An elevated antinuclear antibody titer may be a supplementary argument suggesting a neoplastic etiology.
Service de Médecine interne, Hôpital Saint-Antoine, Paris.
I
I
Delèvaux
J
J
Cabane
E
E
Le Nechet
C
C
Bénit
J
J
Lebas
O
O
Picard
J C
JC
Imbert
D000974:Antibodies, Antinuclear / Q000032:analysis / Q000276:immunology; D002945:Cisplatin / Q000627:therapeutic use; D005260:Female; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D007044:Hysterectomy; D007511:Ischemia / Q000209:etiology*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D011183:Postoperative Complications; D011878:Radiotherapy; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery*
D000974:Antibodies, Antinuclear; D002945:Cisplatin
Un acrosyndrome paranéoplasique.