[Ischemia-reperfusion of the colon following clamping of the abdominal aorta].
Aortic cross-clamping is the cornerstone of abdominal aortic aneurysm surgery. The transient ischemia of the inferior hemisoma, and mainly of the large bowel, is then a current condition, usually well tolerated. At the time of vascular clamps removal, the ischemia-reperfusion syndrome may take place, and evolution toward multiple organ failure is an actual risk. The large bowel has a crucial role in the sequence of events causing ischemia-reperfusion syndrome, even when intestinal ischemia is not evident during aneurysmectomy. In this paper, current concepts of ischemia-reperfusion syndrome are reviewed, and the role of the colon after abdominal aortic cross-clamping for aneurysmectomy is focused. Principles of prevention of MOF from ischemia-reperfusion syndrome are pointed out.
Scorza
R
R
Istituto di Chirurgia Generale e Cardiovascolare, Università degli Studi, Milano.
Ghilardi
G
G
Kunkl
E
E
D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D017091:Colitis, Ischemic / Q000209:etiology; D003106:Colon / Q000098:blood supply; D003250:Constriction; D005260:Female; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D015427:Reperfusion Injury / Q000209:etiology*
L'ischemia-riperfusione del colon conseguente al clampaggio dell'aorta addominale.