Morphology of gonads in pure XY gonadal dysgenesis.
The authors gathered 20 patients having Swyer's syndrome and performed a bilateral gonadectomy and carried out a pathohistologic evaluation of the streak gonads. A more frequent occurrence of streak gonad tumors was found together with the possibility of tracing the merge gonadoblastoma into dysgerminoma (the youngest patient was 15 years old). In 95% of the streak gonads checked an ovary-like stroma was found. In 11 of the patients (55%) one of the above mentioned tumors was found. A frequent finding was the presence of Leydig-type cells, calcifications and the remains of Wolffian canals. In three streak gonads, the corpora albicans-like formations were found.
Department of Obstetrics and Gynecology, School of Medicine, University of Zagreb, Croatia.
B
B
Radaković
S
S
Jukić
D
D
Buković
N
N
Ljubojević
I
I
Cima
D000293:Adolescent; D000328:Adult; D004407:Dysgerminoma / Q000150:complications*; D005260:Female; D006061:Gonadal Dysgenesis, 46,XY / Q000150:complications / Q000473:pathology*; D018238:Gonadoblastoma / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000150:complications*; D010053:Ovary / Q000473:pathology