Interaction of cyanine dyes with nucleic acids. XII.beta-substituted carbocyanines as possible fluorescent probes for nucleic acids detection.
Results of investigations of fluorescent properties of a beta-substituted carbocyanine and its complexes with nucleic acids in comparison with those for the unsubstituted dye are presented. Carbocyanine substituted in polymethine chain has shown promising properties for use as a fluorescent probe in homogeneous systems of nucleic acids detection.
Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv.
S M
SM
Yarmoluk
V B
VB
Kovalska
S S
SS
Lukashov
Y L
YL
Slominskii
D002232:Carbocyanines / Q000138:chemical synthesis / Q000737:chemistry*; D004247:DNA / Q000032:analysis / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D009696:Nucleic Acids / Q000032:analysis* / Q000737:chemistry; D012313:RNA / Q000032:analysis / Q000737:chemistry
D002232:Carbocyanines; D005456:Fluorescent Dyes; D009696:Nucleic Acids; C120934:cyan 2; C120935:cyan 46; D012313:RNA; D004247:DNA