[Reasons for fresh frozen plasma transfusion in a general hospital].
OBJECTIVE
To assess the fresh-frozen plasma (FFP) transfusion indications in a Mexican hospital.


METHODS
A general hospital for federal government employees located in the city of Morelia, State of Michoacan, Mexico.


METHODS
We evaluated all FFP transfusions between February and August, 1998 classifying them as appropriate or inappropriate according to the recent FFP-transfusion guidelines: correction of known coagulation factor deficiencies with bleeding and correction of microvascular bleeding when prothrombin and activated partial thromboplastin time are > 1.6 times normal (coagulation index o CI), urgent reversal of warfarin therapy, antithrombin III deficiency, thrombotic thrombocytopenic purpura treatment, liver transplant and acute disseminated intravascular coagulation.


RESULTS
78 patients with 292 FFP units transfused were analyzed: in 20 patients the indication was clotting support, 16 with CI < 1.5 and four with CI > 1.6, one with blood loss and one with surgical procedure; hypoalbuminemia in 10; hypovolemia in eight; unidentified reason in 33 and others in seven patients. Eleven units (3.76%) were considered properly transfused whereas 281 (96.23%) were inadequately indicated.
Servicio de Hematología, Hospital General Vasco de Quiroga (HG-VQ), Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Morelia, Michoacán. pital@mail.giga.com
L
L
Pita-Ramírez
B E
BE
Cabrera Carbajal
C
C
Ortega Zavala
D000925:Anticoagulants / Q000009:adverse effects; D001778:Blood Coagulation Disorders / Q000628:therapy; D001780:Blood Coagulation Tests; D016913:Blood Component Transfusion / Q000009:adverse effects / Q000706:statistics & numerical data*; D016063:Blood Loss, Surgical; D004211:Disseminated Intravascular Coagulation / Q000628:therapy; D006470:Hemorrhage / Q000628:therapy; D006769:Hospitals, General / Q000706:statistics & numerical data; D006801:Humans; D016031:Liver Transplantation; D008485:Medical Audit; D008800:Mexico; D010949:Plasma; D011300:Preoperative Care; D011697:Purpura, Thrombotic Thrombocytopenic / Q000628:therapy; D014859:Warfarin / Q000009:adverse effects
D000925:Anticoagulants; D014859:Warfarin
Motivos de transfusión de plasma fresco congelado en un hospital general.