The renal actions of moxonidine are mediated by atrial natriuretic peptide and involve the opioid receptors.
Mukaddam-Daher
S
S
Laboratory of Cardiovascular Biochemistry, Centre Hospitalier de L'Universite de Montreal Research Center, Quebec, Canada. mukaddas@medclin.umontreal.ca
Gutkowska
J
J
D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology*; D009320:Atrial Natriuretic Factor / Q000502:physiology*; D004231:Diuresis / Q000187:drug effects* / Q000502:physiology; D007093:Imidazoles / Q000494:pharmacology*; D007668:Kidney / Q000187:drug effects / Q000502:physiology*; D009271:Naltrexone / Q000494:pharmacology; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D011957:Receptors, Opioid / Q000502:physiology*; D015016:Yohimbine / Q000494:pharmacology
D000959:Antihypertensive Agents; D007093:Imidazoles; D011957:Receptors, Opioid; D015016:Yohimbine; D009271:Naltrexone; D009320:Atrial Natriuretic Factor; C043482:moxonidine