Modulation of the synthesis and activation of matrix metalloproteinases in IL-1-treated chondrocytes by antirheumatic drugs.
Institute for Pharmacology and Toxicology, University of Bonn, Germany.
T
T
Sadowski
J
J
Steinmeyer
D000818:Animals; D018501:Antirheumatic Agents / Q000494:pharmacology*; D002358:Cartilage, Articular / Q000187:drug effects / Q000201:enzymology*; D002417:Cattle; D002478:Cells, Cultured; D004789:Enzyme Activation; D006801:Humans; D007375:Interleukin-1 / Q000494:pharmacology*; D008297:Male; D008666:Metalloendopeptidases / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism*; D011509:Proteoglycans / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics; D011994:Recombinant Proteins / Q000494:pharmacology; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014158:Transcription, Genetic / Q000187:drug effects
D018501:Antirheumatic Agents; D007375:Interleukin-1; D011509:Proteoglycans; D012333:RNA, Messenger; D011994:Recombinant Proteins; D008666:Metalloendopeptidases