title: [Acute transverse cervical myelitis following hepatitis B vaccination. Evolution of anti-HBs antibodies].
abstract: BACKGROUND
  The cause and effect relationship between anti-HBV immunization using recombinant vaccine and the development of a neurological event, including flare-ups of multiple sclerosis, is a widely debated issue.
  
  
  METHODS
  A previously asymptomatic 16-year-old girl was a hyper-responder to anti-HBV vaccine. Subsequent to a booster shot of anti-HBV recombinant vaccine, she developed regressive acute cervical transverse myelitis with intrathecal oligochonal IgG secretion and a hypersignal on the MRI T2 sequences of the cord.
  
  
  CONCLUSIONS
  The distinction between a first episode of multiple sclerosis or post-vaccinal acute myelitis in this case will depend upon subsequent course, but this observation points out the very high level of persistent post-vaccinal immunization which can be acquired by a hyper-responder.
authors.affiliation: Clinique de neurologie, HIA Val-de-Grâce, Paris.
authors.forename: J L
authors.initials: JL
authors.lastname: Renard
authors.forename: J S
authors.initials: JS
authors.lastname: Guillamo
authors.forename: J M
authors.initials: JM
authors.lastname: Ramirez
authors.forename: H
authors.initials: H
authors.lastname: Taillia
authors.forename: D
authors.initials: D
authors.lastname: Felten
authors.forename: Y
authors.initials: Y
authors.lastname: Buisson
mesh_terms: D000293:Adolescent; D002574:Cervical Vertebrae; D003937:Diagnosis, Differential; D005260:Female; D006510:Hepatitis B Antibodies / Q000276:immunology*; D017325:Hepatitis B Vaccines / Q000009:adverse effects*; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000175:diagnosis; D009187:Myelitis / Q000175:diagnosis / Q000209:etiology*; D013118:Spinal Cord Diseases / Q000175:diagnosis; D014614:Vaccines, Synthetic
chemical_list: D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines; D014614:Vaccines, Synthetic
vernacular_title: Myélite transverse aiguë cervicale après vaccination contre le virus de l'hépatite B. Evolution sérologique des anticorps anti-HBs.