title: Video-assisted replacement or bypass grafting of the descending thoracic aorta with a new sutureless vascular prosthesis: an experimental study.
abstract: OBJECTIVE
  The feasibility of the video-assisted insertion of a new sutureless vascular prosthesis was studied.
  
  
  METHODS
  Seven sheep, weighing 25 to 35 kg, were operated on under general anesthesia. The animals were intubated with a single-lumen endotracheal tube and placed in the right lateral decubitus position. A thoracoscope was introduced in the 11th intercostal space, and a minithoracotomy (4 to 5 cm) was performed in the seventh intercostal space. After retraction of the lung, a short segment (10 cm) of the descending thoracic aorta was exposed. Our prosthesis was made of Dacron and was specifically designed to be inserted without a suture. After systemic heparinization, the aorta was cross-clamped with two vascular clamps introduced into the thoracic cavity through two 5-mm thoracic incisions. The aorta was either replaced (five cases) or bypass grafted (two cases). At the completion of the procedure, blood pressure was pharmacologically increased (5 mg intravenous bolus of epinephrine), and each anastomosis was checked for bleeding. All animals were killed, and the prosthesis was retrieved for macroscopic examination.
  
  
  RESULTS
  The procedure was completed in each case without extension of the minithoracotomy. Insertion of the prosthesis was easy and fast, and completion of each anastomosis required 10 to 15 minutes. A 3- to 4-mm space between each clip was sufficient for proper attachment. All procedures were performed in less than 120 minutes. No bleeding was observed at the level of each anastomosis, even when a sustained high blood pressure was induced. The proper insertion of the prosthesis and the absence of any anastomotic stenosis was confirmed by means of macroscopic examination.
  
  
  CONCLUSIONS
  Video-thoracoscopic replacement or bypass grafting of the descending thoracic aorta was easy with this new sutureless vascular prosthesis. Minimally invasive vascular surgery might be facilitated with such a prosthesis. However, long-term animal studies are required before human implantation can be undertaken.
authors.affiliation: Department of Thoracic Surgery, Broussais Hospital, Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Zegdi
authors.forename: E
authors.initials: E
authors.lastname: Martinod
authors.forename: O
authors.initials: O
authors.lastname: Fabre
authors.forename: P
authors.initials: P
authors.lastname: Lajos
authors.forename: J N
authors.initials: JN
authors.lastname: Fabiani
mesh_terms: D000818:Animals; D001013:Aorta, Thoracic / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D016343:Monitoring, Intraoperative; D011474:Prosthesis Design; D012756:Sheep; D013537:Sutures; D014743:Videotape Recording