Lignans and polyacetylenes from bupleurum acutifolium
Two new lignans (R,Z)-3-(3,4-dimethoxybenzyl)-2-(3, 4-dimethoxybenzylidene)-gamma-butyrolactone (1) and (2R, 3S)-2-acetoxy-2,3-bis(3,4-dimethoxybenzyl)-gamma-butyrolactone (2), and four new polyacetylenes, (2Z,8E,10E)-heptadeca-2,8,10-triene-4, 6-diyn-1-ol (3), (2E,9Z)-octadeca-2,9-diene-4,6-diyne-1,18-diol (4), (2E,9Z)-18-hydroxy-octadeca-2,9-diene-4,6-diyn-1-yl acetate (5), and (2E,9Z)-1-hydroxy-octadeca-2,9-diene-4,6-diyn-18-yl acetate (6), were isolated and identified from the hexane extract of aerial parts of Bupleurum acutifolium Boiss. Their structures were elucidated by NMR and MS analyses.
Barrero
AF
Instituto de Biotecnologia, Departamento de Quimica Organica, Facultad de Ciencias, Universidad de Granada, Campus de Fuentenueva s/n, 18071 Granada, Spain, and Laboratoire de Chemie Bioorganique et Analytique, Faculte des Sciences et Technique.
Herrador
MM
Akssira
M
Arteaga
P
Romera
JL