[Morphogenesis of Mauthner neurons of Xenopus laevis tadpoles following early unilateral eye enucleation].
The connection between Mauthner neuron (CMN) and visual analyzer in Xenopus laevis tadpoles was studied using these neurons capacity to change their morphogenesis during the development in case of interruption of their connections with afferent fibres. In phase 31 of development tadpoles were subjected to unilateral enucleation of eye. Morphogenesis of contralateral (experimental) and ipsilateral (control) MN with respect to the operated eye was followed up. Comparison with intact Mauthner neuron of the tadpole of the same age who were not exposed to operation was conducted. Contralateral MN were found to be delayed in development phases 47 and 50. This was associated with 1.5-3.3 fold difference in neuron body central section area and 2-3 fold differences in nuclear section area. Three-dimensional reconstruction revealed lower number of cell processes in contralateral MN as well as decline in their length and diameter. Control and intact MN showed no difference similar to experimental and control ones in phase 41. The data obtained indicate that MN of Xenopus laevis tadpole possess powerful ipsilateral connections originating from the side of visual analyzer and contralateral ones from the side of the eye. This affects MN development and in contrast to octavolateral system (including vestibular apparatus and organs of lateral line) controls the contralateral neuron.
Bezgina
E N
EN
Laboratory of Neuron Ultrastructure, Russian Academy of Sciences, Puschino.
Moshkov
D A
DA
Nikitin
V A
VA
Savel'eva
L N
LN
Uteshev
V K
VK
D000818:Animals; D015353:Eye Enucleation; D007839:Functional Laterality / Q000502:physiology; D007091:Image Processing, Computer-Assisted; D007814:Larva / Q000166:cytology / Q000254:growth & development; D009024:Morphogenesis; D009430:Neural Analyzers / Q000166:cytology; D013569:Synapses / Q000502:physiology; D014982:Xenopus laevis / Q000033:anatomy & histology*
Morfogenez Mauthner neĭronov golovastikov shportsevoĭ liagushki v usloviiakh ranneĭ odnostoronneĭ énukleatsii glaza.