title: [Adult onset subacute sclerosing panencephalitis. Report of two cases with atypical presentation].
abstract: Subacute sclerosing panencephalitis is an infrequent central nervous system viral disease and is a late manifestation of persistent infection by a mutant form of measles virus. Since it affects mainly children and teenagers, the diagnosis in older ages is difficult. Its main clinical symptoms are cognitive impairment, behavioral disturbances and myoclonia. We report two males, aged 21 and 22 years old, presenting with the disease with atypical manifestations. One had a catatonic syndrome and the other, amaurosis. The recognition of the different presentation forms of the disease, endemic in developing countries, allows an earlier diagnosis and a more efficient treatment, when available.
authors.affiliation: Unidad de Neurología, Hospital Félix Bulnes C, Santiago de Chile.
authors.forename: V
authors.initials: V
authors.lastname: Valenzuela
authors.forename: M
authors.initials: M
authors.lastname: Miranda
authors.forename: L
authors.initials: L
authors.lastname: Aguilera
authors.forename: L
authors.initials: L
authors.lastname: Fabres
authors.forename: D
authors.initials: D
authors.lastname: Galdames
mesh_terms: D000328:Adult; D017668:Age of Onset; D006801:Humans; D008297:Male; D013344:Subacute Sclerosing Panencephalitis / Q000175:diagnosis*; D013997:Time Factors
vernacular_title: Panencefalitis esclerosante subaguda de inicio en edad adulta: presentación atípica en 2 pacientes.