[Biochemical blood parameters in people with a normal crystalline lens and in cataracts].
The activity of Na+,K+ATPase, gamma-glutamyltranspeptidase, ceruloplasmin, total antioxidative activity of water-soluble antioxidants, the contents of vitamins C and E, free amino-nitrogen and peroxide resistance of erythrocytes were determined at the blood's plasma of healthy persons (120 persons) and suffered from aged cataract (437 persons) of three aged groups (up to 40 years, 40-60 years and elder then 60 years). We have shown, that changes, which has been connected with cataractogenesis and age dependent changes are not equal. The lowering of activity of Na+,K(+)-ATPase, gamma-glutamyltranspeptidase and level of vitamin E was expressed less during the ageing, then during the development of lenses opacification. The increase of activity of oxidase during the cataractogenesis is less significant, then age depended inhibition of this enzyme. The opposite tendency (the lowering of activity at the patients with cataract is more expressed, then compensatory activations of these parameters at the persons of the corresponding age with transparent lenses) was revealed for total antioxidative activity of water-soluble antioxidants.
Metelitsyna
I P
IP
V.P. Filatov Institute of Eyes Diseases and Tissue Therapy of AMS of Ukraine, Odessa.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000975:Antioxidants / Q000378:metabolism; D016022:Case-Control Studies; D002386:Cataract / Q000097:blood*; D002570:Ceruloplasmin / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism; D006801:Humans; D007908:Lens, Crystalline / Q000378:metabolism*; D008875:Middle Aged; D012016:Reference Values; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood; D005723:gamma-Glutamyltransferase / Q000097:blood
D000975:Antioxidants; D002570:Ceruloplasmin; D005723:gamma-Glutamyltransferase; D000254:Sodium-Potassium-Exchanging ATPase
Nekotorye biokhimicheskie parametry krovi u lits s khrustalikami v norme i pri katarakte.