Tomographic convolutional dosimetry of interstitial brachytherapy implants.
A method for approximation of the dose distribution generated by an interstitial brachytherapy implant is introduced. The method employs convolution of raw tomographic data, as a measurement of attenuation of CT pencil beams by the metallic substrate and casing of radioactive seeds. A convolution kernel is introduced in the algorithm for CT image reconstruction such that the tomographic computation results in an approximation of absorbed dose. Error estimates are discussed, and limitations of the method and the domain of validity are discussed. Equivalence with a technique of employing convolution methods to the CT image itself is demonstrated. Calibration and testing on phantom implants is underway.
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University of Maryland Medical System, Department of Radiation Oncology, Baltimore 21201, USA.
D016477:Artifacts; D001918:Brachytherapy / Q000379:methods*; D007091:Image Processing, Computer-Assisted; D015233:Models, Statistical; D019047:Phantoms, Imaging; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D011881:Radiotherapy, Computer-Assisted; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed