Alloimmune neonatal neutropenia treated with rHuG-CSF.
Infants with alloimmune neonatal neutropenia (ANN) may be at risk of life-threatening infection. Various modalities of treatment have been attempted but with differing results. We describe a case treated with rHuG-CSF. The use of rHuG-CSF should be considered in children with ANN especially when associated with life-threatening infection.
Ruggiero
A
A
Department of Pediatrics, Catholic University of Rome, Italy.
Pesaresi
A
A
Scommegna
S
S
Giordano
P
P
Mastrangelo
S
S
Riccardi
R
R
D005260:Female; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use; D016298:Hematopoietic Cell Growth Factors / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000188:drug therapy / Q000276:immunology*; D009503:Neutropenia / Q000188:drug therapy / Q000276:immunology*; D011994:Recombinant Proteins; D016896:Treatment Outcome
D016298:Hematopoietic Cell Growth Factors; D011994:Recombinant Proteins; D016178:Granulocyte-Macrophage Colony-Stimulating Factor