title: [Use of trovafloxacin therapy in community-acquired pneumonia].
abstract: In community-acquired pneumonia (CAP) the pathogenic microorganism is unknown at the time of diagnosis. For that reason the antimicrobial therapy is empirical, based in the clinical picture and the presumptive causal microorganisms. Hospitalization is one of the most important decisions in patients with CAP. Clinical criteria appropriate to identifying those patients requiring hospital admission for antimicrobial administration and clinical control must be defined. The stratification of patients according to the presence of risk factors such as age and co-morbidities permit to predict which are the potential pathogenic microorganisms and their adequate therapy. Trovafloxacin covers all the presumed bacterial spectrum, pharmacokinetics, easiness to be administered and to pass to the oral route, advantageous for all the groups under consideration. Patients older than 65 years of age or with co-morbidities and those that need to be hospitalized receive clear benefits from this antibiotic.
authors.affiliation: Departamento de Medicina, Hospital de Clínicas José de San Martín, Facultad de Medicina, Universidad de Buenos Aires, Argentina. cymluna@fmed.uba.ar
authors.forename: C M
authors.initials: CM
authors.lastname: Luna
authors.forename: R J
authors.initials: RJ
authors.lastname: Gené
mesh_terms: D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000188:drug therapy; D004334:Drug Administration Schedule; D024841:Fluoroquinolones; D006760:Hospitalization; D006801:Humans; D007223:Infant; D008875:Middle Aged; D009287:Naphthyridines / Q000627:therapeutic use*; D018410:Pneumonia, Bacterial / Q000188:drug therapy*; D012307:Risk Factors; D012720:Severity of Illness Index
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D009287:Naphthyridines; C080163:trovafloxacin
vernacular_title: Uso de la trovafloxacina en el tratamiento de la neumonía adquirida en la comunidad.