title: Use of hydroxyapatite bone cement to prevent cerebrospinal fluid leakage through the frontal sinus: technical report.
abstract: OBJECTIVE
  To test the efficacy of a simple technique of frontal sinus obliteration during low frontal craniotomy using hydroxyapatite cement instead of more traditional methods, such as pericranial flaps, free muscle or adipose grafts, lumbar drainage, or fibrin glue.
  
  
  METHODS
  Eight patients undergoing low frontal craniotomy for intradural surgery had the frontal sinus obliterated by careful removal of mucosa followed by filling of the sinus with hydroxyapatite bone cement. No other adjuncts for preventing cerebrospinal fluid leakage through the sinus were used.
  
  
  RESULTS
  At an average follow-up of 9 months, there were no cerebrospinal fluid leaks, infections, instances of resorption, or cosmetic deformities.
  
  
  CONCLUSIONS
  Hydroxyapatite bone cement seems to be a simple and effective method for frontal sinus obliteration and prevention of cerebrospinal fluid leakage.
authors.affiliation: Department of Surgery, University of Michigan Medical Center, Ann Arbor, USA.
authors.forename: D A
authors.initials: DA
authors.lastname: Ross
authors.forename: L J
authors.initials: LJ
authors.lastname: Marentette
authors.forename: B G
authors.initials: BG
authors.lastname: Thompson
authors.forename: J S
authors.initials: JS
authors.lastname: Haller
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001672:Biocompatible Materials / Q000627:therapeutic use*; D001843:Bone Cements / Q000627:therapeutic use*; D002555:Cerebrospinal Fluid / Q000378:metabolism*; D003399:Craniotomy / Q000009:adverse effects*; D017886:Durapatite / Q000627:therapeutic use*; D005260:Female; D005626:Frontal Sinus / Q000378:metabolism*; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control*
chemical_list: D001672:Biocompatible Materials; D001843:Bone Cements; D017886:Durapatite