title: Synthesis of a nucleoside bioconjugate system as a potential anti-HIV agent.
abstract: Synthesis and anti-HIV data for a bioconjugate molecule incorporating a HIV protease inhibitor (A74704) and a HIV RT inhibitor (d4T) are presented.
authors.affiliation: Department of Chemistry, University of Iowa, Iowa City 52242, USA.
authors.forename: S
authors.initials: S
authors.lastname: Van Calenbergh
authors.forename: V
authors.initials: V
authors.lastname: Nair
mesh_terms: D019380:Anti-HIV Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D002460:Cell Line; D017320:HIV Protease Inhibitors / Q000737:chemistry; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D018894:Reverse Transcriptase Inhibitors / Q000737:chemistry; D016339:Spectrometry, Mass, Fast Atom Bombardment; D018119:Stavudine / Q000737:chemistry; D013402:Sugar Alcohols / Q000737:chemistry; D014633:Valine / Q000031:analogs & derivatives / Q000737:chemistry
chemical_list: D019380:Anti-HIV Agents; D017320:HIV Protease Inhibitors; D009705:Nucleosides; D018894:Reverse Transcriptase Inhibitors; D013402:Sugar Alcohols; C065300:A 74704; D018119:Stavudine; D014633:Valine