A case of sequential anti-stress medication in a patient with major depression resistant to amine-reuptake inhibitors.
One of the predictive factors of treatment-resistant depression is the syndrome of relative insulin resistance, i.e. adipositas, mild hypertension and a family history of type-2 diabetes. Such a case is here reported with a good outcome to anti-stress medication, including ketoconazole and lithium.
Bech
P
P
Psychiatric Research Unit, Frederiksborg General Hospital, Hillerod, Denmark.
Raabaek Olsen
L
L
Jarløv
N
N
Hammer
M
M
Schütze
T
T
Breum
L
L
D000588:Amines / Q000037:antagonists & inhibitors*; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001008:Anxiety Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D003687:Dehydroepiandrosterone / Q000097:blood; D003865:Major Depressive Disorder / Q000150:complications / Q000188:drug therapy / Q000523:psychology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use; D018757:GABA Modulators / Q000627:therapeutic use; D006801:Humans; D006854:Hydrocortisone / Q000037:antagonists & inhibitors / Q000652:urine; D007654:Ketoconazole / Q000494:pharmacology / Q000627:therapeutic use*; D016651:Lithium Carbonate / Q000494:pharmacology / Q000627:therapeutic use*; D008803:Mianserin / Q000627:therapeutic use; D008875:Middle Aged; D010076:Oxazepam / Q000627:therapeutic use; D011379:Prognosis; D011569:Psychiatric Status Rating Scales; D012702:Serotonin Antagonists / Q000627:therapeutic use; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D012720:Severity of Illness Index; D013315:Stress, Psychological / Q000188:drug therapy* / Q000523:psychology
D000588:Amines; D000928:Antidepressive Agents; D003687:Dehydroepiandrosterone; D005473:Fluoxetine; D018757:GABA Modulators; D006854:Hydrocortisone; D007654:Ketoconazole; D016651:Lithium Carbonate; D008803:Mianserin; D010076:Oxazepam; D012702:Serotonin Antagonists; D017367:Selective Serotonin Reuptake Inhibitors