title: [Evaluation of efficacy and safety of intrabronchial specific immunotherapy with allergy medication against allergies to house mites among patients with bronchial asthma].
abstract: The purpose of this study was to evaluate efficacy and safety of local immunotherapy with inhaled allergens of house dust mites in asthmatic patients. An opened study was conducted in a group of 16 patients who have undergone 7 months course of immunotherapy. It has been shown statistically significant decrease in a score of clinical symptoms and in administered medications. On the other hand it has been demonstrated statistically significant increase of PEF in these patients. A decrease in specific and non-specific bronchial hyperreactivity has been revealed in bronchial provocation tests. Specific, local immunotherapy seems to be efficacious and well-tolerated way of hyposensitisation in house dust mite allergic patients.
authors.affiliation: Kliniki Alergologii, Akademii Medycznej w Białymstoku.
authors.forename: Z
authors.initials: Z
authors.lastname: Zietkowski
mesh_terms: D000293:Adolescent; D000318:Adrenergic beta-Agonists / Q000494:pharmacology / Q000627:therapeutic use*; D000328:Adult; D000485:Allergens / Q000276:immunology*; D000818:Animals; D001249:Asthma / Q000276:immunology* / Q000628:therapy*; D001985:Bronchial Provocation Tests / Q000379:methods; D004391:Dust; D005260:Female; D006632:Histamine; D006636:Histamine Release / Q000276:immunology; D006801:Humans; D007167:Immunotherapy / Q000706:statistics & numerical data; D008297:Male; D008925:Mites / Q000276:immunology*; D018343:Receptors, Adrenergic, beta-2 / Q000187:drug effects; D012449:Safety; D012680:Sensitivity and Specificity; D016896:Treatment Outcome
chemical_list: D000318:Adrenergic beta-Agonists; D000485:Allergens; D004391:Dust; D018343:Receptors, Adrenergic, beta-2; D006632:Histamine
vernacular_title: Ocena skuteczności i bezpieczeństwa dooskrzelowej immunoterapii swoistej preparatem alergenowym roztoczy kurzu domowego u chorych na astme oskrzelowa.