title: Synthesis and antiviral activities of 1,3-oxathiolanyl nucleosides with 5-hydroxymethyl substituent.
abstract: Novel 1,3-oxathiolanyl pyrimidine nucleosides with 5-hydroxymethyl substituent were synthesized starting from D-mannose and evaluated for antiviral activities against HIV-1, HSV type 1,2 and HCMV.
authors.affiliation: College of Pharmacy, Seoul National University, Korea.
authors.forename: M W
authors.initials: MW
authors.lastname: Chun
authors.forename: S P
authors.initials: SP
authors.lastname: Choi
authors.forename: M J
authors.initials: MJ
authors.lastname: Kim
authors.forename: C J
authors.initials: CJ
authors.lastname: Bae
authors.forename: H R
authors.initials: HR
authors.lastname: Moon
authors.forename: H D
authors.initials: HD
authors.lastname: Kim
authors.forename: L S
authors.initials: LS
authors.lastname: Jeong
mesh_terms: D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D015497:HIV-1 / Q000187:drug effects; D006564:Herpesviridae / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009705:Nucleosides / Q000138:chemical synthesis* / Q000494:pharmacology*
chemical_list: D000998:Antiviral Agents; D009705:Nucleosides