[Effect of mexidol and its structural components on carbohydrate level and lipid peroxidation in acute stress].
The influence of mexidol (3-hydroxy-6-methyl-2-ethylpyridine succinate) and its structural components (3-hydroxy-6-methyl-2-ethylpyridine and sodium succinate) and pyridoxine hydrochloride on carbohydrate content and lipid peroxidation was studied in the mouse liver under conditions of stress. Under stress conditions mexidol and pyridoxine exerted positive effects on peroxidation processes; mexidol also normalised glycogen content in the liver.
Deviatkina
T A
TA
Ukraine Medical Stomatological Academy, Poltava.
Lutsenko
R V
RV
Vazhnichaia
E M
EM
Smirnov
L D
LD
D000208:Acute Disease; D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D005947:Glucose / Q000378:metabolism; D015227:Lipid Peroxidation; D008099:Liver / Q000378:metabolism*; D008112:Liver Glycogen / Q000378:metabolism; D051379:Mice; D010847:Picolines / Q000737:chemistry / Q000494:pharmacology*; D013312:Stress, Physiological / Q000378:metabolism*
D000975:Antioxidants; D008112:Liver Glycogen; D010847:Picolines; C070020:emoxypine succinate; D005947:Glucose
Vliianie meksidola i ego strukturnykh komponentov na soderzhanie uglevodov i perekisnoe okislenie lipidov pri ostrom stresse.