title: Hepatoprotective activity of Ficus racemosa leaf extract on liver damage caused by carbon tetrachloride in rats.
abstract: An extract of the leaves of Ficus racemosa Linn. (Moraceae) was evaluated for hepatoprotective activity in rats by inducing chronic liver damage by subcutaneous injection of 50% v/v carbon tetrachloride in liquid paraffin at a dose of 3 mL/kg on alternate days for a period of 4 weeks. The biochemical parameters SGOT, SGPT, serum bilirubin and alkaline phosphatase were estimated to assess the liver function. The activity of extract was also comparable to a standard liver tonic (Neutrosec).
authors.affiliation: Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta - 700 032, India.
authors.forename: S C
authors.initials: SC
authors.lastname: Mandal
authors.forename: T K
authors.initials: TK
authors.lastname: Maity
authors.forename: J
authors.initials: J
authors.lastname: Das
authors.forename: M
authors.initials: M
authors.lastname: Pal
authors.forename: B P
authors.initials: BP
authors.lastname: Saha
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000378:metabolism; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy* / Q000473:pathology; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy* / Q000473:pathology; D008099:Liver / Q000473:pathology*; D010936:Plant Extracts / Q000627:therapeutic use; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D010936:Plant Extracts; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D001663:Bilirubin