Combined idiopathic retroperitoneal and mediastinal fibrosis with pericardial involvement.
We report the case of a 54-year-old woman with renal failure related to bilateral hydronephrosis. Clinical and radiologic findings were consistent with retroperitoneal fibrosis associated with pleuro-pericardial involvement. These features matched criteria for combined idiopathic retroperitoneal fibrosis and idiopathic mediastinal fibrosis. There are few reported cases of pericardial involvement in this combined disorder. In our observation, nuclear-magnetic resonance was the radiologic procedure of choice for aortic exploration. The responsibility of therapeutic agents (beta-adrenoreceptor-blocking drugs and ergotamine) and therapeutic options for the sclerosing disease are also discussed. Bilateral ureteral stents and corticosteroids produced favorable outcome without recurrence one year after treatment was stopped.
Klisnick
A
A
Service de Néphrologie et de Réanimation Médicale Polyvalente, Hôpital Gabriel-Montpied, Clermont-Ferrand, France.
Fourcade
J
J
Ruivard
M
M
Baud
O
O
Souweine
B
B
Boyer
L
L
Deteix
P
P
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D005260:Female; D005355:Fibrosis / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D006869:Hydronephrosis / Q000150:complications; D009682:Magnetic Resonance Spectroscopy; D008477:Mediastinal Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008875:Middle Aged; D010490:Pericardial Effusion / Q000175:diagnosis; D010494:Pericarditis, Constrictive / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D051437:Renal Insufficiency / Q000209:etiology; D012185:Retroperitoneal Fibrosis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D015607:Stents; D014057:Tomography, X-Ray Computed
D000305:Adrenal Cortex Hormones