title: Induction of labor with vaginal prostaglandin-E2 in grand multiparous women with one previous cesarean section.
abstract: OBJECTIVE
  To review the outcome of induction of labor with vaginal prostaglandin-E2 in grand multiparous women with one previous cesarean section.
  
  
  METHODS
  Twenty-six grand multiparous women with one previous cesarean section were induced with vaginal prostaglandin-E2.
  
  
  RESULTS
  Twenty (76.9%) women delivered vaginally and six (23.1%) women delivered by emergency cesarean section. The mean duration of labor was 6 +/- 3.6 h. There was no uterine rupture or dehiscence. There was one neonatal death and two stillbirths.
  
  
  CONCLUSIONS
  Our limited study suggests that induction of labor with vaginal prostaglandin-E2 in selected grand multiparous women with one previous cesarean section may be a reasonable option. However, further studies are needed to document its safety.
authors.affiliation: Department of Obstetrics and Gynecology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
authors.forename: T Y
authors.initials: TY
authors.lastname: Yamani
authors.forename: A A
authors.initials: AA
authors.lastname: Rouzi
mesh_terms: D000328:Adult; D002585:Cesarean Section; D015232:Dinoprostone / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015552:Injections, Intralesional; D007751:Labor, Induced / Q000379:methods*; D010120:Oxytocics / Q000008:administration & dosage*; D010298:Parity; D011247:Pregnancy; D011256:Pregnancy Outcome; D014621:Vagina / Q000187:drug effects
chemical_list: D010120:Oxytocics; D015232:Dinoprostone