title: Src autoinhibition: let us count the ways.
abstract: Src family tyrosine kinases are key cellular signaling enzymes whose catalytic activities are tightly controlled. Recent structural and mutational studies have revealed additional intricacies in the autoinhibitory mechanisms by which catalytic activity is repressed.
authors.forename: S R
authors.initials: SR
authors.lastname: Hubbard
mesh_terms: D002384:Catalysis; D004789:Enzyme Activation; D008958:Models, Molecular; D018909:src Homology Domains; D019061:src-Family Kinases / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism
chemical_list: D019061:src-Family Kinases