title: Antimicrobial activity of Elaeocarpus sphaericus.
abstract: Antibacterial activity of petroleum ether (PE), benzene (BE), chloroform (CE), acetone (AE) and ethanol (EE) extracts of dried Elaeocarpus sphaericus fruit was investigated against 28 gram-positive and gram-negative bacteria using the disc diffusion and plate dilution methods. The AE fraction showed marked antimicrobial activity against ten organisms. BE was active against Salmonella typhimurium and Morganella morganii, and EE against Plesiomonas shigelloides, Shigella flexnerii and Sh. sonneii. The alkaloids and flavonoids present in the plant appear to be of chemotherapeutic interest.
authors.affiliation: Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi - 221 005, India.
authors.forename: R K
authors.initials: RK
authors.lastname: Singh
authors.forename: G
authors.initials: G
authors.lastname: Nath
mesh_terms: D000470:Alkaloids / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D005419:Flavonoids / Q000494:pharmacology; D006027:Glycosides / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D012997:Solvents; D013256:Steroids / Q000494:pharmacology
chemical_list: D000470:Alkaloids; D000900:Anti-Bacterial Agents; D005419:Flavonoids; D006027:Glycosides; D010936:Plant Extracts; D012997:Solvents; D013256:Steroids