title: A continuous quality improvement initiative reduces inappropriate prescribing of prophylactic antibiotics for endoscopic procedures.
abstract: OBJECTIVE
  Despite the availability of guidelines, most gastroenterologists do not administer prophylactic antibiotics appropriately to patients having endoscopic procedures. In 1994 we recognized that in our endoscopy unit, many patients were receiving antibiotics without proper indication. We devised a continuous quality improvement initiative to analyze and improve this problem.
  
  
  METHODS
  Divisional guidelines for the appropriate administration of prophylactic antibiotics for endoscopy were drawn up in 1995. By retrospective analysis of our comprehensive endoscopy database we compared the rate of prophylactic antibiotic administration, and the proportion of antibiotics that were indicated before and after adoption of the divisional guidelines.
  
  
  RESULTS
  A total of 1427 endoscopic procedures were done during a 6-month period in 1994 (before adoption of guidelines). Of these, 55 (3.85%) received antibiotics. In a 6-month period in 1996 after adoption of guidelines, 1452 procedures were performed and 29 of these (1.99%) received antibiotics. The odds ratio for receiving antibiotics appropriately in 1996, compared with 1994, was 3.4 (chi2 p = 0.016). Given an annual volume of 2900 procedures in our endoscopy unit, approximately 54 patients will avoid unnecessary antibiotics, yielding a cost saving of $1128 per year.
  
  
  CONCLUSIONS
  A divisional continuous quality improvement initiative on antibiotic prophylaxis for endoscopy significantly reduced the proportion of patients receiving antibiotics unnecessarily. This quality improvement initiative enhanced the quality of care for patients having endoscopy and yielded a small cost saving. These improvements were achieved with minimal effort and cost to the division.
authors.affiliation: Division of Gastroenterology, Duke University Medical Center, Durham, North Carolina 27710, USA.
authors.forename: J B
authors.initials: JB
authors.lastname: O'Connor
authors.forename: S S
authors.initials: SS
authors.lastname: Sondhi
authors.forename: K D
authors.initials: KD
authors.lastname: Mullen
authors.forename: A J
authors.initials: AJ
authors.lastname: McCullough
mesh_terms: D000046:Academic Medical Centers / Q000191:economics; D019072:Antibiotic Prophylaxis / Q000191:economics; D017046:Cost Savings; D004363:Drug Utilization; D016099:Endoscopy, Gastrointestinal / Q000191:economics; D006801:Humans; D009820:Ohio; D017410:Practice Guidelines as Topic; D011785:Quality Assurance, Health Care; D012189:Retrospective Studies