title: Synthesis of the tBuSATE pronucleotide of AZT by two different synthetic approaches.
abstract: A large scale synthesis of the tBuSATE pronucleotide of AZT was required for in vivo studies. A comparative synthesis of this derivative by phosphoramidite and monophosphate approaches is reported.
authors.affiliation: Laboratoire de Chimie Bioorganique, U.M.R. 5625 C.N.R.S.-U.S.T.L., Université de Montpellier II, France.
authors.forename: M
authors.initials: M
authors.lastname: Lannuzel
authors.forename: D
authors.initials: D
authors.lastname: Egron
authors.forename: J L
authors.initials: JL
authors.lastname: Imbach
authors.forename: G
authors.initials: G
authors.lastname: Gosselin
authors.forename: C
authors.initials: C
authors.lastname: Périgaud
mesh_terms: D019380:Anti-HIV Agents / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D015215:Zidovudine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D019380:Anti-HIV Agents; D015215:Zidovudine