Inwardly rectifying potassium channels.
Inwardly rectifying potassium (Kir) channels regulate the resting membrane potential of the cell and thereby modulate the electrical activity of cardiac and neuronal cells, insulin secretion and epithelial K(+) transport. Considerable progress in understanding the molecular structure of Kir channels and the way in which they are regulated by extracellular and intracellular modulators has been made during the past year.
Reimann
F
F
University Laboratory of Physiology, Parks Road, Oxford, OX1 3PT, UK.
Ashcroft
F M
FM
D000818:Animals; D001477:Bartter Syndrome / Q000235:genetics; D006801:Humans; D006946:Hyperinsulinism / Q000235:genetics; D007003:Hypoglycemia / Q000235:genetics; D015221:Potassium Channels / Q000737:chemistry / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D024661:Potassium Channels, Inwardly Rectifying; D011487:Protein Conformation
D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying