[A survey of clinically used drugs in PVR: a review].
Colchicine, corticosteroids, daunomycin, fluorouracil, heparin and retinoids have been used in man and show an effect in different stages of the development of PVR. In this survey the effect of each drug is described and the clinical studies are discussed. This survey shows that there are many drugs that in addition to surgery might influence the natural course of clinical PVR during different stages. However, the only drug for which a significant reduction in the number of reoperations has been demonstrated in a randomized prospective trial is daunomycin. Literature search by medline.
Faude
F
F
Klinik und Poliklinik für Augenheilkunde der Universität Leipzig. faudef@server3.medizin.uni-leipzig.de
Heimann
K
K
Wiedemann
P
P
D000818:Animals; D004341:Drug Evaluation / Q000379:methods; D006801:Humans; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D018630:Vitreoretinopathy, Proliferative / Q000188:drug therapy*
Klinisch pharmakologische Studien zur Behandlung der PVR: eine Ubersicht.