[Unexpected accumulation of 111In-antimyosin in the chest in an area corresponding to the radiation field of a squamous cell lung carcinoma].
We report a patient with squamous cell lung carcinoma treated with radiation therapy who suffered two clinical episodes suggestive of myocarditis, one before radiation therapy was administered and the other three months after ending treatment. In both episodes, 111In-antimyosin scintigraphies were performed, finding an unexpected antimyosin uptake in the irradiated area was in the second episode. After analyzing the possible etiologies of the image mentioned, we reached the conclusion that the most likely mechanism of antimyosin uptake could also be attribute to myosin released by myocardial and endothelial cells damage by ionizing radiation.
Peñafiel Ramírez
A
A
Unidad de Medicina Nuclear, Hospital Son Dureta, Palma de Mallorca, Baleares, 07014, España.
Pardo Masferrer
J
J
Peña Viloria
C
C
D000911:Antibodies, Monoclonal; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D007205:Indium Radioisotopes; D008168:Lung / Q000000981:diagnostic imaging; D008175:Lung Neoplasms / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009218:Myosins / Q000276:immunology*; D013902:Radiography, Thoracic; D011877:Radionuclide Imaging; D011878:Radiotherapy / Q000009:adverse effects*; D013909:Thorax / Q000000981:diagnostic imaging*
D000911:Antibodies, Monoclonal; D007205:Indium Radioisotopes; D009218:Myosins
Acumulación inesperada de 111 In-antimiosina a nivel torácico en un área que se correspondía con el campo de irradiación de un carcinoma escamoso pulmonar.