title: The otolaryngologic manifestations of gastroesophageal reflux: when is a pH study indicated?
abstract: OBJECTIVE
  The aim of this study was to evaluate the pertinence of pH studies for persistent ear, nose, and throat (ENT) symptoms and their eventual relationship to gastroesophageal reflux (GER).
  
  
  METHODS
  Retrospective analysis was performed of age, reason for referral, pH study, treatment, and follow-up of patients with ENT symptoms suspected to have GER.
  
  
  RESULTS
  Of 3,000 esophageal pH studies performed over 16 years, 105 children were referred for ENT symptoms by an otorhinolaryngologist to rule out GER. Mean age was 33 months; 65% were boys. Reasons for referral included (number and mean age): stridor (n = 31, 8 months), laryngomalacia (n = 18, 13 months), recurrent otitis (n = 12, 42 months), laryngitis (n = 16, 50 months), dysphonia (n = 14, 59 months), laryngeal papillomatosis (n = 8, 62 months), sinusitis (n = 5, 56 months), and dysphagia (n = 1). Overall, 41% of study results were positive: stridor (58%), laryngomalacia (61%), laryngitis (56%) and sinusitis (40%). Patients with otitis, dysphonia and laryngeal papillomatosis had GER in 1%, 14%, and 25%, respectively. Follow-up in the three larger groups of patients showed resolution of the ENT symptoms after medical treatment of the reflux in 83% of patients with stridor and reflux, 86% with laryngitis and reflux, and 80% with laryngomalacia and reflux. Four fundoplications were performed: one neurologically impaired patient, and four nonresponders.
  
  
  CONCLUSIONS
  The authors recommend that a pH study be performed in children with stridor, laryngomalacia, laryngitis, and sinusitis when faced with failure of the usual treatment. However, a pH study does not seem as beneficial for recurrent otitis, dysphonia, or laryngeal papillomatosis.
authors.affiliation: Department of Pediatric Surgery, Sainte-Justine Hospital, Montreal, Quebec, Canada.
authors.forename: S
authors.initials: S
authors.lastname: Bouchard
authors.forename: M
authors.initials: M
authors.lastname: Lallier
authors.forename: S
authors.initials: S
authors.lastname: Yazbeck
authors.forename: A
authors.initials: A
authors.lastname: Bensoussan
mesh_terms: D002648:Child; D002675:Child, Preschool; D004947:Esophagus / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D006863:Hydrogen-Ion Concentration; D015994:Incidence; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods; D010038:Otorhinolaryngologic Diseases / Q000175:diagnosis / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors; D012680:Sensitivity and Specificity