[The specific activity of new drug forms of dibunol].
The specific activity of new drug forms (tablets, suppositories, ointments) of dubinal was studies on models of ischemic damage to the heart, toxic hepatitis, aseptic inflammation, damage to the skin and mucosa of the large intestine. It was found that the drug forms under study possessed a cardioprotective, hepatoprotective, anti-inflammatory, and wound-healing effect. This may serve as a prerequisite to their further clinical study.
Zyrianov
S K
SK
Department of Pharmacology No. 2, Bashkir State Medical University, Ufa, Russia.
Nasyrov
Kh M
KhM
Shikova
Iu V
IuV
Likhoded
V A
VA
Gilev
V G
VG
D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage*; D001207:Asepsis; D002084:Butylated Hydroxytoluene / Q000008:administration & dosage*; D002252:Carbon Tetrachloride Poisoning / Q000150:complications / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy / Q000209:etiology; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D007249:Inflammation / Q000139:chemically induced / Q000188:drug therapy; D007410:Intestinal Diseases / Q000188:drug therapy; D051379:Mice; D009203:Myocardial Infarction / Q000188:drug therapy / Q000209:etiology; D009205:Myocarditis / Q000139:chemically induced / Q000188:drug therapy; D009824:Ointments; D051381:Rats; D013488:Suppositories; D013607:Tablets; D013997:Time Factors; D014456:Ulcer / Q000188:drug therapy
D000975:Antioxidants; D009824:Ointments; D013488:Suppositories; D013607:Tablets; D002084:Butylated Hydroxytoluene
Spetsificheskaia aktivnost' novykh lekarstvennykh form dibunola.