Specific and nonspecific immunity in the prevention of spontaneous tumours.
Antitumour vaccines cannot cure established tumours. However, tumour cells engineered to release cytokines can halt progression to cancer by inhibiting the angiogenic phenotype of pretumoural cells and activating tumour-associated leukocytes, thus they might prove useful in immunizing those at risk of cancer.
Lollini
P L
PL
Istituto di Cancerologia, Viale Filopanti 22, 40126 Bologna, Italy.
Forni
G
G
D000818:Animals; D019496:Cancer Vaccines / Q000494:pharmacology; D016207:Cytokines / Q000494:pharmacology; D006801:Humans; D009369:Neoplasms / Q000235:genetics / Q000276:immunology* / Q000517:prevention & control*; D009389:Neovascularization, Pathologic / Q000276:immunology / Q000517:prevention & control
D019496:Cancer Vaccines; D016207:Cytokines