title: [Treatment of children with malignant brain tumors].
abstract: The current treatment of children with malignant brain tumors is reviewed. Multidisciplinary treatment is essential for malignant gliomas or glioblastoma. The prognosis of children with glioblastoma remains dismal and a new treatment approach needs to be established. Recent aggressive multi-drug chemotherapy in combination with radiotherapy and surgery have markedly improved the treatment of children with medulloblastoma and primary intracranial malignant germ cell tumors. The number of long-term survivors and even cure rates have been increasing.
authors.affiliation: Department of Neurosurgery, Kumamoto University Medical School, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Ushio
authors.forename: M
authors.initials: M
authors.lastname: Kochi
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D001932:Brain Neoplasms / Q000628:therapy*; D002648:Child; D003131:Combined Modality Therapy; D018237:Germinoma / Q000628:therapy; D005910:Glioma / Q000628:therapy; D006801:Humans