title: The impact of residual renal function and total body water volume on achieving adequate dialysis in CAPD.
abstract: OBJECTIVE
  The objective is to evaluate the impact of residual renal function (RRF) and total body water (TBW) on achieving adequate dialysis.
  
  
  METHODS
  Sixty three CAPD patients performing four 2 liter exchanges daily were evaluated for RRF, total weekly Kt/V (TWKt/V), total weekly creatinine clearance (TWCC) and TBW.
  
  
  RESULTS
  In patients with residual renal function (N = 41), TWKt/V and TWCC were 2.2 +/- 0.8 and 77.4 +/- 24.5 L, respectively. In patients without RRF (N = 22), TWKt/V was 1.6 +/- 0.4 and TWCC 42.6 +/- 9.2 L. TBW correlated negatively with TWKt/V in the group without RRF (r = -0.75, P<0.001).
  
  
  CONCLUSIONS
  It is not possible for larger patients without RRF treated with CAPD (2L x 4 exchanges) to achieve the acceptable targets for TWKt/V and TWCC due to TBW.
authors.affiliation: Department of Medicine, The George Washington University Medical Center, Washington, DC 20037, USA.
authors.forename: H
authors.initials: H
authors.lastname: Gao
authors.forename: S Q
authors.initials: SQ
authors.lastname: Lew
authors.forename: C
authors.initials: C
authors.lastname: Ronco
authors.forename: G J
authors.initials: GJ
authors.lastname: Mishkin
authors.forename: J P
authors.initials: JP
authors.lastname: Bosch
mesh_terms: D000328:Adult; D000368:Aged; D001834:Body Water; D003404:Creatinine / Q000378:metabolism; D006801:Humans; D007668:Kidney / Q000502:physiology*; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory
chemical_list: D003404:Creatinine