"Mixed inhibitors" of HIV-reverse transcriptase: synthesis and antiviral activity.
Some "AZT-HEPT" and "ddC-HEPT" conjugates were designed, synthesized and evaluated for their anti-HIV activity.
Pontikis
R
R
Institut Curie, Section Recherche, UMR-176 CNRS-IC, Paris, France.
Note
R
R
Dechaux
E
E
Guillaumel
J
J
Aubertin
A M
AM
Grierson
D S
DS
Monneret
C
C
D019380:Anti-HIV Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D015195:Drug Design; D054303:HIV Reverse Transcriptase / Q000037:antagonists & inhibitors; D015497:HIV-1 / Q000187:drug effects; D015498:HIV-2 / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D018894:Reverse Transcriptase Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*
D019380:Anti-HIV Agents; D018894:Reverse Transcriptase Inhibitors; D054303:HIV Reverse Transcriptase