title: Study of arterial blood pressure by a Windkessel-type model: influence of arterial functional properties.
abstract: OBJECTIVE
  To analyse the performance of a Windkessel blood pressure (BP) modeling of arterial compliance adjusted in a dynamic fashion according to a non-linear relationship between the arterial compliance (AC) and BP. Non invasive measurements of the radial BP waveform (MILLAR tonometry) were compared to those constructed by an electric simulator reproducing the model in a symmetrical network subdivided into 121 segments. We introduced at cardiac level the aortic stroke volume (Doppler echocardiography) and the dynamic values of compliance (relation of compliance-to pressure, constant or variable) whether the model was linear or non linear, measured by high resolution Doppler (NIUS 02) for each subject.
  
  
  RESULTS
  At the radial artery segment the modelled BP obtained by the non linear model of AC was not significantly different from the measured BP wave, while in the linear model (AC constant at mean BP level) the systolic BP was significantly underestimated. (*P < 0.05).
  
  
  CONCLUSIONS
  This work shows the limits inherent in simplification of arterial compliance in the Windkessel model using constant parameters. This demonstrates the influence of the dynamic properties of the arterial wall in a conduction artery on the level of systolic and diastolic BP.
authors.affiliation: CNRS IN2P3, Grenoble, France.
authors.forename: B
authors.initials: B
authors.lastname: Diourté
authors.forename: J P
authors.initials: JP
authors.lastname: Siché
authors.forename: V
authors.initials: V
authors.lastname: Comparat
authors.forename: J P
authors.initials: JP
authors.lastname: Baguet
authors.forename: J M
authors.initials: JM
authors.lastname: Mallion
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D003198:Computer Simulation; D006801:Humans; D008955:Models, Cardiovascular