[The activity of free-radical lipid-peroxidative reactions in the acute and late periods of severe craniocerebral trauma].
Severe craniocerebral injury is shown to result in intensification of processes of lipid peroxidation (LPO), decline in activity of the antioxidant system, which facts lead to further damage to the injured brain caused by products of LPO processes. Activity of LPO processes is recordable as is decline in activity of the antioxidant system after the treatment administered and in 12 and 24 months following the injury sustained as well. The authors recommend that natural and synthetic antioxidants be included into a complex of measures designed to treat severe craniocerebral injury.
Sutkovoĭ
D A
DA
Pedachenko
E G
EG
Malyshev
O B
OB
Guk
A P
AP
Troian
A I
AI
Morozov
A N
AN
Glushchenko
N V
NV
Fedosenko
T N
TN
D000208:Acute Disease; D000975:Antioxidants / Q000378:metabolism; D001930:Brain Injuries / Q000097:blood*; D005609:Free Radicals / Q000097:blood; D006801:Humans; D015227:Lipid Peroxidation; D008163:Luminescent Measurements; D017382:Reactive Oxygen Species / Q000378:metabolism; D013997:Time Factors
D000975:Antioxidants; D005609:Free Radicals; D017382:Reactive Oxygen Species
Issledovanie aktivnosti svobodnoradikal'nykh perekisno-okislitel'nykh reaktsiĭ v ostrom i otdalennom periode tiazheloĭ cherepno-mozgovoĭ travmy.