title: Survival analysis of Thai patients with non-small-cell lung cancer undergoing surgical resection.
abstract: This study examined the survival duration among patients with non-small-cell lung cancer (NSCLC) undergoing surgical resection from January 1988 to December 1992 at the Central Chest Hospital, Thailand. Patients were followed-up until death or survival as of September 1997. Survival durations for different stages were analysed by Kaplan-Meier analysis and log rank test. A total of 127 patients with histologically proved NSCLC underwent 79 lobectomies, 9 bilobectomies, 39 pneumonectomies during 1988-1992. The mean age was 60 years (SD 10.4). There were 103 males and 24 females. Percentage of histologic types were: 59 per cent adenoCA, 35 per cent squamous cell CA, and 6 per cent large cellCA. Survival analysis was feasible in 88 patients, 38 alive and 50 deaths. 1-yr, 2-yr, and 5-yr survival were as following: 85 per cent, 78 per cent, and 60 per cent in stage 1 (n = 47); 70 per cent, 50 per cent, and 30 per cent in stage 2 (n = 12); and 54 per cent, 23 per cent, and 15 per cent in stage 3a (n = 29) [log rank 19.06, df 2, p = 0.0001]. Based on the present study, the survival outcome in patients with lung cancer beyond stage 1 is uniformly poor. Measures should be made to diagnose early stage disease and expedite surgery in order that a better survival outcome can be achieved.
authors.affiliation: Division of Medicine, Central Chest Hospital, Nonthaburi, Thailand.
authors.forename: P
authors.initials: P
authors.lastname: Riantawan
authors.forename: T
authors.initials: T
authors.lastname: Koanantakool
authors.forename: T
authors.initials: T
authors.lastname: Chotivatanapong
authors.forename: M
authors.initials: M
authors.lastname: Wongsangiem
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome