title: A new semisynthesis of paclitaxel from baccatin III.
abstract: A new method for the semisynthesis of paclitaxel (Taxol) from baccatin III via a dioxo-oxathiazolidine intermediate is reported.
authors.affiliation: Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061-0212, USA.
authors.forename: E
authors.initials: E
authors.lastname: Baloglu
authors.forename: D G
authors.initials: DG
authors.lastname: Kingston
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000138:chemical synthesis*; D002855:Chromatography, Thin Layer; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D017239:Paclitaxel / Q000138:chemical synthesis*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D043823:Taxoids
chemical_list: D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D007202:Indicators and Reagents; D043823:Taxoids; C073950:baccatin III; D017239:Paclitaxel