title: Synthesis of novel isomeric dideoxydidehydronucleosides.
abstract: Methodologies for the synthesis of novel isomeric dideoxynucleosides with unsaturation in the carbohydrate moiety have been developed. An example of the synthesis (Isod4A) is presented. Antiviral studies are in progress.
authors.affiliation: Department of Chemistry, University of Iowa, Iowa City 52242, USA.
authors.forename: V
authors.initials: V
authors.lastname: Nair
authors.forename: S
authors.initials: S
authors.lastname: Bera
authors.forename: T
authors.initials: T
authors.lastname: Mickle
authors.forename: S
authors.initials: S
authors.lastname: Van Calenbergh
mesh_terms: D018360:Crystallography, X-Ray; D015224:Dideoxynucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D007536:Isomerism; D009690:Nucleic Acid Conformation; D013056:Spectrophotometry, Ultraviolet
chemical_list: D015224:Dideoxynucleosides