title: "Mixed inhibitors" of HIV-reverse transcriptase: synthesis and antiviral activity.
abstract: Some "AZT-HEPT" and "ddC-HEPT" conjugates were designed, synthesized and evaluated for their anti-HIV activity.
authors.affiliation: Institut Curie, Section Recherche, UMR-176 CNRS-IC, Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Pontikis
authors.forename: R
authors.initials: R
authors.lastname: Note
authors.forename: E
authors.initials: E
authors.lastname: Dechaux
authors.forename: J
authors.initials: J
authors.lastname: Guillaumel
authors.forename: A M
authors.initials: AM
authors.lastname: Aubertin
authors.forename: D S
authors.initials: DS
authors.lastname: Grierson
authors.forename: C
authors.initials: C
authors.lastname: Monneret
mesh_terms: D019380:Anti-HIV Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D015195:Drug Design; D054303:HIV Reverse Transcriptase / Q000037:antagonists & inhibitors; D015497:HIV-1 / Q000187:drug effects; D015498:HIV-2 / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D018894:Reverse Transcriptase Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*
chemical_list: D019380:Anti-HIV Agents; D018894:Reverse Transcriptase Inhibitors; D054303:HIV Reverse Transcriptase