Early reactive neutrophil changes in an infant with Kawasaki syndrome.
An infant with Kawasaki syndrome presenting with fever, rash, and a high percentage of neutrophils with toxic granulation is reported. The peripheral blood smears of the patient showed a high proportion of neutrophils with marked vacuoles and toxic granulations. The reactive changes in neutrophils could be helpful in the early detection of the disease, especially in infants younger than 6 months of age who are at high risk for development of coronary artery disease.
Ruggiero
A
A
Department of Pediatrics, Catholic University of Rome, Italy.
Delogu
A B
AB
Riccardi
R
R
Mastrangelo
S
S
Segni
G
G
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007223:Infant; D009080:Mucocutaneous Lymph Node Syndrome / Q000473:pathology* / Q000628:therapy; D009504:Neutrophils / Q000473:pathology*; D013997:Time Factors
D007074:Immunoglobulin G; D016756:Immunoglobulins, Intravenous