IgG response to some mycobacterial antigens in selected leprosy patients.
Serum samples from selected leprosy patients with putative tuberculosis were tested by indirect ELISA to determine the level of IgG antibody against six mycobacterial antigen preparations. PCR-positive leprosy patients were confirmed with PGL-I ELISA. A ratio of antibodies to antigens of tuberculosis and leprosy was found to be a valuable serological marker for tuberculosis in long-treated leprosy patients.
Rafi
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Department of Pathobiology, Faculty of Medicine, Tabriz University of Medical Sciences, Iran.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000917:Antibody Formation; D000942:Antigens, Bacterial / Q000276:immunology*; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006017:Glycolipids / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D016233:Immunotherapy, Active; D007918:Leprosy / Q000150:complications / Q000276:immunology* / Q000628:therapy; D008875:Middle Aged; D009161:Mycobacterium / Q000276:immunology*; D012680:Sensitivity and Specificity; D014374:Tuberculin Test; D014376:Tuberculosis / Q000097:blood / Q000150:complications / Q000276:immunology*
D000942:Antigens, Bacterial; D006017:Glycolipids; D007074:Immunoglobulin G; C045169:phenolic glycolipid I, Mycobacterium leprae