title: [The role of endogenous and exogenous factors in the development of psychoses in organic dementias in later life].
abstract: Influence of different exogenic and endogenic factors (including the very organic process) as analyzed in 231 patients of psychiatric hospital with organic dementia: vascular (VD)--57 cases, senile dementia of Alzheimer's type (SDAT)--29 individuals, dementia conditioned by a combination of vascular and senile-atrophic processes (VD/SDAT)--37 patients, Alzheimer's disease (70 patients) and Pick's disease (38 cases). 160 patients (the study group) had psychotic disorders, 71 patients (the control group) hadn't such disorders. The most frequent (98.2%) and the most various psychotic syndromes (especially delirium and hallucination syndromes) were observed in VD, SDAT and VD/SDAT. A rate of organic process progression was less in patients of the study group as compared with a control one. Prevalence in the study group of cases with endogenic-constitutional predisposition to psychoses development was significant. The role of the other exocerebral factors in origin of psychoses was not so pronounced; among them psychogenias were rather significant, their frequency was 4 times higher in the study group than in the control one. The relationship of psychotic syndromes with origin, stage and progression rate of dementia might indicate a leading role of the organic process in their genesis.
authors.forename: V G
authors.initials: VG
authors.lastname: Budza
authors.forename: V A
authors.initials: VA
authors.lastname: Medvedev
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D003704:Dementia / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D004198:Disease Susceptibility; D006801:Humans; D008875:Middle Aged; D011599:Psychopathology; D011618:Psychotic Disorders / Q000175:diagnosis / Q000209:etiology* / Q000523:psychology; D013597:Systems Analysis; D013997:Time Factors
vernacular_title: Rol' éndogennykh i ékzogennykh faktorov v razvitii psikhozov pri organicheskikh dementsiiakh pozdnego vozrasta.