title: The origins of the artificial cornea: Pellier de Quengsy and his contribution to the modern concept of keratoprosthesis.
abstract: There has been little recognition of the French ophthalmologist Guillaume Pellier de Quengsy and his contribution to the problem of artificial cornea (keratoprosthesis). This fact that he was the first to propose such a device was seldom acknowledged, and usually as a secondary reference. Based on the examination of original texts (1789), this study demonstrates that Pellier not only proposed an essentially correct keratoprosthesis, but also suggested a porous prosthetic skirt, a revolutionary concept which is currently fundamental to artificial cornea research.
authors.affiliation: Department of Biomaterials and Polymer Research, Lions Eye Institue, Nedlands, Western Australia.
authors.forename: T V
authors.initials: TV
authors.lastname: Chirila
authors.forename: C R
authors.initials: CR
authors.lastname: Hicks
mesh_terms: D003315:Cornea; D005137:Eye, Artificial / Q000266:history*; D005602:France; D049671:History, 18th Century; D049672:History, 19th Century; D006801:Humans; D009885:Ophthalmology / Q000266:history*