Systemic sclerosis (scleroderma) in two iron ore mines.
Six males with systemic sclerosis were observed in the work forces of two iron ore mines. The usual spectrum of clinical features encountered in systemic sclerosis patients were present. Histologic examination of pulmonary tissue was performed on three of the cases and showed features of both silicosis and scleroderma but to different degrees and stages of development. Exposure to high levels of silica-containing dusts had occurred in all six cases.
Martin
J R
JR
Faculty of Medicine, Memorial University of Newfoundland, St. John's, Canada. john.warren@nf.sympatico.ca
Griffin
M
M
Moore
E
E
Lochead
J A
JA
Edwards
A C
AC
Williams
J
J
Khraishi
M M
MM
D000328:Adult; D000368:Aged; D004391:Dust / Q000009:adverse effects*; D006801:Humans; D019570:Inhalation Exposure / Q000009:adverse effects*; D007501:Iron; D008297:Male; D008875:Middle Aged; D008906:Mining; D016273:Occupational Exposure / Q000009:adverse effects*; D012595:Scleroderma, Systemic / Q000209:etiology*; D012822:Silicon Dioxide / Q000009:adverse effects*
D004391:Dust; D012822:Silicon Dioxide; D007501:Iron