title: [Erectile dysfunction after radical prostatectomy: value of preoperative programming of intracavernous injections].
abstract: OBJECTIVE
  Vasoactive drugs used for self-administered intracavernous injections are currently the reference treatments for erectile dysfunction after radical prostatectomy. The acceptability of and compliance with this treatment often limit their use. This study analysed these two parameters as a function of the type of andrological management decided before radical prostatectomy.
  
  
  METHODS
  From January 1996 to January 1997, 45 sexually active patients, aged 52 to 69 years, requiring radical prostatectomy without preservation of the nervi erigentes, for localized prostate cancer, were included in this prospective study. Before the operation all 45 patients were informed about the high risk of erectile dysfunction following radical prostatectomy. Fifteen patients (group 1) did not receive any particular advice concerning the management of erectile dysfunction after radical prostatectomy, but were possibly referred for an andrology consultation depending on their complaints. Fifteen patients (group 2) were systematically referred for an andrology consultation three months after radical prostatectomy for information about the available treatment options. For 15 patients (group 3), the andrology consultation (3 months after the operation) had been planned before radical prostatectomy to perform a test injection of prostaglandin E1. The injections, started before the operation in this group 3, therefore constituted an integral part of the global management of prostate cancer. All these patients were followed for at least 1 year in the urology department.
  
  
  RESULTS
  Only 7 of the 15 patients of group 1 consulted an andrologist. Five of these patients received a test intracavernous injection versus 14 in group 2 and 15 in group 3. The 5 patients of group 1 who received an intracavernous injection accepted this modality as treatment versus 8 in group 2 and 12 in group 3. After one year, 4, 5 and 9 patients in groups 1, 2 and 3, respectively, continued intracavernous injections.
  
  
  CONCLUSIONS
  The management of erectile dysfunction after radical prostatectomy must start with the decision to operate. Systematic encouragement to use intracavernous injections after radical prostatectomy helps to improve access to this treatment for impotence. The acceptability, and especially the compliance, appear to be better in patients in whom intracavernous injections were integrated into the global management of their prostate cancer.
authors.affiliation: Service d'Urologie, Hôpital Foch, Suresnes, France.
authors.forename: T
authors.initials: T
authors.lastname: Lebret
authors.forename: J M
authors.initials: JM
authors.lastname: Hervé
authors.forename: L
authors.initials: L
authors.lastname: Yonneau
authors.forename: A
authors.initials: A
authors.lastname: Colau
authors.forename: Z
authors.initials: Z
authors.lastname: Kassardjian
authors.forename: P
authors.initials: P
authors.lastname: Barré
authors.forename: P M
authors.initials: PM
authors.lastname: Lugagne-Delpon
authors.forename: H
authors.initials: H
authors.lastname: Botto
mesh_terms: D000368:Aged; D004334:Drug Administration Schedule; D007172:Erectile Dysfunction / Q000209:etiology* / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D010353:Patient Education as Topic; D011300:Preoperative Care; D011446:Prospective Studies; D011468:Prostatectomy / Q000009:adverse effects*; D011471:Prostatic Neoplasms / Q000601:surgery*; D012725:Sexual Behavior; D014662:Vasoconstrictor Agents / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014662:Vasoconstrictor Agents
vernacular_title: Dysfonction érectile après prostatectomie radicale: intérêt de la programmation des injections intracaverneuses avant l'intervention.