title: Cockroach and other inhalant allergies in infantile asthma.
abstract: BACKGROUND
  Infantile asthma is commonly thought to be caused by viral respiratory infections and exposure to second-hand cigarette smoke. Allergy has not been felt to be a major cause of infantile asthma and infants and small children are not commonly skin tested.
  
  
  OBJECTIVE
  To determine the frequency of skin test reactivity in asthmatic children less than 3 years of age.
  
  
  METHODS
  We evaluated 196 (50 female/146 male) children with infantile asthma for allergy. Infantile asthma was defined as three or more episodes of wheezing in a child less than 3 years of age. A careful environmental history was obtained on all children. All were skin tested to alternaria, cat, dog, cockroach, and house dust mites (HDM) extracts using the prick technique with the Greer Dermapik.
  
  
  RESULTS
  Forty-five percent of the infants and children tested had at least one positive skin test. 51/196 (26%) of the children were skin test positive to cockroach, 17.3% to HDM, 13.8% to cat, 6.6% to alternaria, and 6.1% positive to dog. For the 49 children who were less than 1 year of age, 28.5% were positive to cockroach, 10.2% to HDM, 10.2% to cats, 4% to alternaria, and 0% to dog.
  
  
  CONCLUSIONS
  Allergy to cockroach and other indoor allergens may be a significant contributor to infantile asthma in a rural setting. Skin testing children with infantile asthma may provide useful information for institution of environmental controls measures in the child's home.
authors.affiliation: Department of Pediatrics, West Virginia University, School of Medicine, Morgantown 26506-9214, USA.
authors.forename: N W
authors.initials: NW
authors.lastname: Wilson
authors.forename: N P
authors.initials: NP
authors.lastname: Robinson
authors.forename: M B
authors.initials: MB
authors.lastname: Hogan
mesh_terms: D000280:Administration, Inhalation; D000393:Air Pollutants; D000485:Allergens / Q000008:administration & dosage / Q000276:immunology*; D000528:Alternaria / Q000276:immunology; D000818:Animals; D001249:Asthma / Q000276:immunology*; D002415:Cats / Q000276:immunology; D002675:Child, Preschool; D003058:Cockroaches / Q000276:immunology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008925:Mites / Q000276:immunology
chemical_list: D000393:Air Pollutants; D000485:Allergens