Determination of some insect repellents in cosmetic products by high-performance thin-layer chromatography.
A simple and reliable thin-layer chromatographic method for the determination of N,N-diethyl-m-toluamide (DEET) and dimethyl phthalate (DMP) in raw material and cosmetic products was developed and validated. A benzene-diethyl ether-cyclohexane (5:3:2, v/v/v) solvent system was used for quantitative evaluation of chromatograms. The chromatographic zones corresponding to the spots of DEET and DMP on the silica gel plates were scanned in the reflectance/absorbance mode at 230 nm. The method was found to be reproducible and convenient for the quantitative analysis of DEET and DMF in raw material and cosmetic products.
Markovic
G
G
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Belgrade, Serbia, Yugoslavia.
Agbaba
D
D
Stakic
D Z
DZ
Vladimirov
S
S
D002855:Chromatography, Thin Layer / Q000379:methods*; D003358:Cosmetics / Q000737:chemistry*; D003671:DEET / Q000032:analysis*; D007302:Insect Repellents / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
D003358:Cosmetics; D007302:Insect Repellents; D003671:DEET