Bicyclonucleosides and ring-chain interconversion.
Four types of bicyclonucleosides differing in the easiness of their ring-chain interconversion have been prepared, some exhibited anti-HIV activity and the ratio of their cyclic and open-chain forms could have some bearing on their biological activity.
Tronchet
J M
JM
University of Geneva, Department of Pharmaceutical Chemistry, Switzerland.
Zsély
M
M
Brenas
L
L
Lassout
O
O
Grand
E
E
Seuret
P
P
Grigorov
M
M
Rivara-Minten
E
E
Geoffroy
M
M
D019380:Anti-HIV Agents / Q000737:chemistry* / Q000494:pharmacology; D015497:HIV-1 / Q000187:drug effects; D015498:HIV-2 / Q000187:drug effects; D009705:Nucleosides / Q000737:chemistry* / Q000494:pharmacology
D019380:Anti-HIV Agents; D009705:Nucleosides