Vipera palaestinae antivenin.
A review is presented of the methods developed to raise the neutralizing capacity of anti-Vipera palaestinae (Vp) venom. These include formaldehyde detoxification of the venom, immunization with carboxymethyl-cellulose-bound neurotoxin, and enzymatic fragmentation of the neutralizing antibody.
Moroz
C
C
Molecular Immunology Unit, Felsenstein Medical Research Center, Rabin Medical Center, Petach Tikva, Israel.
D000818:Animals; D000997:Antivenins / Q000276:immunology / Q000627:therapeutic use*; D010450:Endopeptidases / Q000187:drug effects*; D005557:Formaldehyde / Q000494:pharmacology; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000302:isolation & purification / Q000494:pharmacology*; D007074:Immunoglobulin G / Q000302:isolation & purification / Q000494:pharmacology; D009498:Neurotoxins / Q000276:immunology / Q000302:isolation & purification; D012909:Snake Bites / Q000628:therapy*; D014757:Viper Venoms / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000633:toxicity; D017819:Viperidae
D000997:Antivenins; D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D009498:Neurotoxins; D014757:Viper Venoms; D005557:Formaldehyde; D010450:Endopeptidases; C041605:hemorrhagic proteinase IV