[Mitochondrial megaconia and pleioconia in the rat brain as possible and adaptive reactions in lethal radiation and radio-modified injuries].
Electron microscopic study of sensomotor area of brain and cerebellar cortex was conducted in 38 outbred albino rats, following 200 Gy irradiation including that combined with preceding effect of hypoxia or 48 hrs long active vigilance. Mitochondrial megaconia and pleioconia were found 4 hrs after the irradiation in neuronal cytoplasm and axoplasm of neuropil unmyelinated and myelinated fibres. These processes were more significant after radio-modified injuries. It may be suggested that mitochondrial megaconia and pleioconia are adaptive reactions to de-energization following the action of superpowerful extreme factors.
Zabolotskiĭ
N N
NN
Department of Neurology Military Medical Academy, St.Petersburg.
Onishchenko
L S
LS
Galeev
I Sh
ISh
D000222:Adaptation, Physiological / Q000528:radiation effects*; D000818:Animals; D002531:Cerebellum / Q000502:physiology / Q000528:radiation effects* / Q000648:ultrastructure; D003593:Cytoplasm / Q000528:radiation effects; D002534:Hypoxia, Brain / Q000473:pathology; D008297:Male; D008928:Mitochondria / Q000502:physiology / Q000528:radiation effects* / Q000648:ultrastructure; D009413:Nerve Fibers, Myelinated / Q000528:radiation effects; D009474:Neurons / Q000528:radiation effects / Q000648:ultrastructure; D019581:Neuropil / Q000528:radiation effects; D011833:Radiation Injuries, Experimental / Q000473:pathology* / Q000503:physiopathology; D051381:Rats; D013003:Somatosensory Cortex / Q000502:physiology / Q000528:radiation effects* / Q000648:ultrastructure; D015996:Survival Rate
Mitokhondrial'nye megakoniia i pleĭokoniia v golovnom mozge krys kak vozmozhnye adaptatsionnye reaktsii pri letal'nykh radiatsionnykh i radiomodifitsirovannykh povrezhdeniiakh.