title: DEPRES II (Depression Research in European Society II): a patient survey of the symptoms, disability and current management of depression in the community. DEPRES Steering Committee.
abstract: The first pan-European survey of depression in the community (DEPRES I) demonstrated that 17% of the general population suffer from depression (major depression, minor depression, or depressive symptoms). This article describes findings from a second phase of DEPRES (DEPRES II), in which detailed interviews based on a semi-structured questionnaire (78 questions) were conducted with 1884 DEPRES I participants who had suffered from depression and who consulted a healthcare professional about their symptoms during the previous 6 months. The mean time from onset of depression was 45 months, and the most commonly experienced symptoms during the latest period were low mood (76%), tiredness (73%) and sleep problems (63%). During the previous 6 months, respondents had been unable to undertake normal activities because of their depression for a mean of 30 days, and a mean of 20 days of work had been lost to depression by those in paid employment. Approximately one-third of respondents (30%) had received an antidepressant during the latest period of depression. Significantly more respondents given a selective serotonin reputake inhibitor found that their treatment made them feel more like their normal self than those given a tricyclic antidepressant, and fewer reported treatment-related concentration lapses, weight problems, and heavy-headedness (all P < 0.05). Approximately two-thirds of respondents (70%) had received no antidepressant therapy during the latest period of depression, and prescription of benzodiazepines alone, which are not effective against depression, was widespread (17%). There is a need for education of healthcare professionals to encourage appropriate treatment of depression.
authors.affiliation: Institute of Psychiatry, De Crespigny Park, London, UK.
authors.forename: A
authors.initials: A
authors.lastname: Tylee
authors.forename: M
authors.initials: M
authors.lastname: Gastpar
authors.forename: J P
authors.initials: JP
authors.lastname: Lépine
authors.forename: J
authors.initials: J
authors.lastname: Mendlewicz
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D003625:Data Collection; D003866:Depressive Disorder / Q000453:epidemiology* / Q000523:psychology / Q000628:therapy; D018450:Disease Progression; D005062:European Union / Q000706:statistics & numerical data; D006801:Humans; D011795:Surveys and Questionnaires
chemical_list: D000928:Antidepressive Agents