title: Miniaturized FRET assays and microfluidics: key components for ultra-high-throughput screening.
abstract: Assay miniaturization applicable across a wide range of target classes, along with automation and process integration, are well-recognized goals for ultra-high-throughput screening on an industrial scale. This report summarizes the implementation of fluorescence resonance energy transfer (FRET)-based biochemical and cell-based assays in 3456-well NanoWelltrade mark assay plates using key components of Aurora's ultra-high-throughput screening system.
authors.affiliation: Aurora Biosciences Corporation, 11010 Torreyana Road, San Diego, CA 92121, USA.
authors.initials: L
authors.lastname: Mere
authors.initials: T
authors.lastname: Bennett
authors.initials: P
authors.lastname: Coassin
authors.initials: P
authors.lastname: England
authors.initials: B
authors.lastname: Hamman
authors.initials: T
authors.lastname: Rink
authors.initials: S
authors.lastname: Zimmerman
authors.initials: P
authors.lastname: Negulescu