Transcellular biosynthesis of eicosanoids.
Transcellular biosynthesis of prostacyclin (platelets/endothelial cells), cysteinyl-leukotrienes (granulocytes/endothelial cells) or lipoxins (granulocytes/renal cells) constitute a new approach to the therapy of thrombosis, ischaemic heart disease and glomerulonephritis.
Gryglewski
R J
RJ
Department of Pharmacology, Medical College, Jagiellonian University, Kraków, Poland.
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use; D001241:Aspirin / Q000009:adverse effects / Q000627:therapeutic use; D001249:Asthma / Q000139:chemically induced / Q000378:metabolism; D001792:Blood Platelets / Q000378:metabolism; D015777:Eicosanoids / Q000096:biosynthesis*; D004727:Endothelium / Q000166:cytology / Q000378:metabolism; D005921:Glomerulonephritis / Q000378:metabolism; D006098:Granulocytes / Q000378:metabolism; D006801:Humans; D007668:Kidney / Q000166:cytology / Q000378:metabolism; D017202:Myocardial Ischemia / Q000378:metabolism; D013927:Thrombosis / Q000378:metabolism
D000894:Anti-Inflammatory Agents, Non-Steroidal; D015777:Eicosanoids; D001241:Aspirin