title: Occupational exposure to lead--granulometric distribution of airborne lead in relation to risk assessment.
abstract: The amount of airborne lead absorbed by the body during occupational exposure depends not only on lead concentration in workplace air, but also on the granulometric distribution of the aerosol. The Occupational Safety and Health Administration (OSHA) set the lead Permissible Exposure Limit (PEL) at 50 micrograms/m3 on the basis of Bernard's model and a number of assumptions, including assumption "C", which predicts that the first 12.5 micrograms/m3 are made up of fine particles (aerodynamic diameter < 1 micron) whereas the remaining 12.5 micrograms/m3 consist of particles > 1 micron. Occupational exposure to airborne lead at a concentration of 50 micrograms/m3 and a granulometric distribution calculated according to the above mentioned assumption, leads, in the model, to a mean blood level of 40 micrograms/dl. In the present study, we tested the validity of assumption "C" in the environmental air of a factory that manufactured crystal glassware containing 24% lead oxide. An 8-stage impactor was used to measure the particle size of airborne dust collected from personal and area samplings. Results indicate that, on the whole, assumption "C" cannot be considered valid in the work environment investigated in this study. As a result, lead absorption levels in exposed workers may be noticeably different from those predicted by the OSHA model. We therefore suggest that in order to make a correct evaluation of the risk of occupational exposure to lead, it is essential to integrate total airborne lead concentration with a measurement of the granulometric distribution of the aerosol.
authors.affiliation: Institute of Occupational Medicine, School of Medicine, Catholic University of S. Cuore, Rome, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Carelli
authors.forename: O
authors.initials: O
authors.lastname: Masci
authors.forename: A
authors.initials: A
authors.lastname: Altieri
authors.forename: N
authors.initials: N
authors.lastname: Castellino
mesh_terms: D000336:Aerosols; D000395:Air Pollutants, Occupational / Q000032:analysis* / Q000097:blood; D004391:Dust / Q000032:analysis; D004784:Environmental Monitoring / Q000379:methods; D006801:Humans; D007854:Lead / Q000032:analysis* / Q000097:blood; D008452:Maximum Allowable Concentration; D016273:Occupational Exposure; D010316:Particle Size; D013054:Spectrophotometry, Atomic
chemical_list: D000336:Aerosols; D000395:Air Pollutants, Occupational; D004391:Dust; D007854:Lead