title: Leiomyosarcoma of the larynx. Review of the literature and report of two cases.
abstract: Leiomyosarcoma of the larynx is an extremely rare malignancy. Until now, only 35 cases have been reported, and only 19 were reported in English. We present 2 new cases observed in the last 3 years at our department. Correct histologic diagnosis can only be made on immunohistochemical and electron microscopic grounds. A 65-year-old man previously treated for a premalignant vocal cord lesion and a 31-year-old woman who previously underwent operation on a benign vocal cord lesion are presented. Only surgical treatment (total laryngectomy and endolaryngeal laser resection) was performed. Thirty-six and 22 months after the initial surgical intervention, both patients are alive and well, with no evidence of local recurrence or distant metastasis.
authors.affiliation: Department of Otorhinolaryngology, Albert Szent-Györgyi Medical University, Szeged, Hungary.
authors.forename: R
authors.initials: R
authors.lastname: Paczona
authors.forename: J
authors.initials: J
authors.lastname: Jóri
authors.forename: L
authors.initials: L
authors.lastname: Tiszlavicz
authors.forename: J
authors.initials: J
authors.lastname: Czigner
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000601:surgery; D007825:Laryngectomy / Q000379:methods; D053685:Laser Therapy; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000601:surgery; D008297:Male