[Stereometry of temporal peripapillary atrophy in early-stage open-angle glaucoma].
OBJECTIVE
To study the significance of temporal peripapillary atrophy in the pathogenesis of open-angle glaucoma in its early stage.


METHODS
Sterometry of temporal peripapillary atrophy was performed in 46 eyes of 46 patients with early-stage open-angle glaucoma and in 38 eyes of 38 healthy persons using a Heidelberg Retina Tomograph.


RESULTS
The area of peripapillary atrophy averaged 0.78 +/- 0.46 mm2 in glaucoma eyes and 0.55 +/- 0.33 mm2 in controls. The difference was significant (p < 0.002). Its volume averaged 0.04 +/- 0.04 mm3 in glaucoma eyes and 0.02 +/- 0.02 mm3 in controls. The difference was significant (p < 0.001). Both the area and volume of disc cupping were significantly greater in glaucoma eyes than in controls (p < 0.001). The volume of rim of the disc was significantly smaller in eyes with symmetrical cupping than asymmetrical one (p < 0.001). Both the area and volume of peripapillary atrophy were significantly greater in eyes with asymmetrical cupping than symmetrical one (p < 0.001 each).


CONCLUSIONS
The presence, shape and size of temporal peripapillary atrophy are closely associated with the pathogenesis of open-angle glaucoma in its early stage.
Yoshikawa
K
K
Yoshikawa Eye Clinic, Nakamachi Machida, Japan.
Wakamatsu
Y
Y
Ishibashi
Y
Y
D000328:Adult; D001284:Atrophy; D002829:Choroid / Q000473:pathology; D005260:Female; D005902:Glaucoma, Open-Angle / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009898:Optic Disk