Effects of electroacupuncture at neiguan on myocardial microcirculation in rabbits with acute myocardial ischemia.
This paper reports the effects of electroacupuncture (EA) at Neiguan (P 6) on myocardial microcirculation and electrical activity observed in rabbits with acute myocardial ischemia (AMI) by employing the vascular casting method and taking monophasic action potential (MAP) as an index. It was found that in the ischemic border zone of the heart, the electrical excitability was strengthened, the shortening of the phase repolarization inhibited, and the number of the micrangia increased in some degree following EA. This suggests that EA can relieve arteriolospasm, inhibit extreme dilatation of blood capillaries, modulate imbalance of micro-vasomotion of the coronary artery, improve myocardial blood-supply, and promote normalization of electrical activities of the ischemia myocardium. This fact not only elucidates the recovery mechanism of the ischemic myocardium promoted by EA at Neiguan (P 6), but also provides morphological basis for the theory of relationship between Neiguan of the Pericardium Meridian and the heart.
Cao
Q
Q
Institute of Acupuncture and Moxibustion, China Academy of Traditional Chinese Medicine, Beijing, China.
Liu
J
J
Chen
S
S
Han
Z
Z
D000200:Action Potentials; D015669:Acupuncture Points; D000818:Animals; D003331:Coronary Vessels; D015671:Electroacupuncture; D005260:Female; D006321:Heart / Q000503:physiopathology*; D008297:Male; D008833:Microcirculation; D017202:Myocardial Ischemia / Q000503:physiopathology*; D011817:Rabbits; D011897:Random Allocation