Radical scavenging activity of phenylpropanoid glycosides in Caryopteris incana.
In our screening program for antioxidants from traditional drugs and foodstuffs, one new phenylpropanoid glycoside, incanoside, was isolated together with four known phenylpropanoid glycosides, verbascoside, isoverbascoside, phlinoside A, and 6-O-caffeoyl-beta-D-glucose from the whole plant of Caryopteris incana (Thunb.) Miq. On the basis of chemical evidence and spectral analysis data, the structure of incanoside was determined to be 1-O-(3,4-dihydroxyphenyl)ethyl-O-beta-D-glucopyranosyl (1-->2)-alpha-L-rhamnopyranosyl(1-->3)-6-O-caffeoyl-beta-D- glucopyranoside. The four phenylpropanoid glycosides exhibited potent radical scavenging activity against DPPH, hydroxyl (.OH), and superoxide anion (O2-.) radicals.
Gao
J J
JJ
Faculty of Agriculture, Yamagata University, Japan.
Igalashi
K
K
Nukina
M
M
D000107:Acetylation; D015764:Bepridil / Q000031:analogs & derivatives / Q000737:chemistry; D001713:Biphenyl Compounds; D002240:Carbohydrate Sequence; D002681:China; D004578:Electron Spin Resonance Spectroscopy; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000302:isolation & purification; D005609:Free Radicals / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D006868:Hydrolysis; D017665:Hydroxyl Radical / Q000737:chemistry; D008969:Molecular Sequence Data; D010851:Picrates; D010946:Plants, Medicinal / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013481:Superoxides / Q000737:chemistry
D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005609:Free Radicals; D006027:Glycosides; D010851:Picrates; C121317:incanoside; D013481:Superoxides; D017665:Hydroxyl Radical; D015764:Bepridil; C004931:1,1-diphenyl-2-picrylhydrazyl