title: Retinoblastoma as a congenital primary intracranial tumor.
abstract: This report describes a rare case of retinoblastoma presenting as a congenital primary intracranial tumor. A 7-day-old infant presented with generalized seizures. He had a family history of retinoblastoma. Computed tomography of the brain revealed a midline suprasellar tumor without evidence of retinal tumors. Subtotal resection of the tumor was performed. Histopathologic findings were diagnostic of retinoblastoma. The patient sustained profound ischemic brain damage and was not given definitive further therapy. He died days after the diagnosis was made. Retinoblastoma can present as an isolated ectopic intracranial tumor without associated retinal tumors.
authors.affiliation: Department of Oncology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
authors.forename: A
authors.initials: A
authors.lastname: Al Omari
authors.forename: M M
authors.initials: MM
authors.lastname: Mustafa
authors.forename: R
authors.initials: R
authors.lastname: Hessler
authors.forename: A
authors.initials: A
authors.lastname: Rejjal
authors.forename: A
authors.initials: A
authors.lastname: Kattan
mesh_terms: D001932:Brain Neoplasms / Q000150:complications / Q000151:congenital* / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012175:Retinoblastoma / Q000150:complications / Q000151:congenital* / Q000175:diagnosis*; D012640:Seizures / Q000209:etiology