title: Raman and infrared studies of nucleosides at high pressures: I. Adenosine.
abstract: Room temperature Raman and infrared (IR) spectra of crystalline adenosine at pressures between 1 atm and 10 GPa are reported. Vibrational modes were identified through assignments in the literature. Many modes were found to increase in frequency with pressure; however, some irregularities were observed. Discontinuities were observed in numerous Raman and IR modes near 2.5 GPa, indicating a phase transition. The modes associated with the glycosidic bond shift significantly down in frequency near this pressure, suggesting a weakening of the associated bond. The IR modes associated with hydrogen-stretching motions were found to decrease in frequency with pressure.
authors.affiliation: Department of Physics and Astronomy, University of Toledo, OH 43606, USA.
authors.forename: K C
authors.initials: KC
authors.lastname: Martin
authors.forename: D A
authors.initials: DA
authors.lastname: Pinnick
authors.forename: S A
authors.initials: SA
authors.lastname: Lee
authors.forename: A
authors.initials: A
authors.lastname: Anderson
authors.forename: W
authors.initials: W
authors.lastname: Smith
authors.forename: R H
authors.initials: RH
authors.lastname: Griffey
authors.forename: V
authors.initials: V
authors.lastname: Mohan
mesh_terms: D000241:Adenosine / Q000737:chemistry*; D015394:Molecular Structure; D011312:Pressure; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman
chemical_list: D000241:Adenosine