title: [Current therapeutic orientation toward testicular germ cell tumors].
abstract: Personal experience in a case of primary germinal tumor of the testis in advanced state is described. The initial treatment was chemioterapy: the patient received four complete cycles of cisplatin-based chemoterapy (PEB scheme). A surgical treatment consisted of a radical inguinal orchiectomy with high ligation of the spermatic cord at the deep inguinal ring associated with interaortocaval lymphonodes dissection. Actually, after two years from the beginning of treatment, the patient is well, without signs of neoplasm disease.
authors.affiliation: Università degli Studi di Roma La Sapienza.
authors.forename: M
authors.initials: M
authors.lastname: Catani
authors.forename: R
authors.initials: R
authors.lastname: De Milito
authors.forename: M
authors.initials: M
authors.lastname: Chiaretti
authors.forename: E
authors.initials: E
authors.lastname: Cortesi
authors.forename: W
authors.initials: W
authors.lastname: Anselmi
authors.forename: G
authors.initials: G
authors.lastname: Manili
authors.forename: B
authors.initials: B
authors.lastname: Tomei
authors.forename: V
authors.initials: V
authors.lastname: Terrinoni
authors.forename: G
authors.initials: G
authors.lastname: Bianchi
authors.forename: M
authors.initials: M
authors.lastname: Rengo
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood; D001761:Bleomycin / Q000008:administration & dosage; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003456:Cryptorchidism / Q000150:complications; D005047:Etoposide / Q000008:administration & dosage; D018237:Germinoma / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008026:Ligation; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D009919:Orchiectomy; D013085:Spermatic Cord / Q000601:surgery; D013736:Testicular Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D014408:Biomarkers, Tumor; D018997:Chorionic Gonadotropin, beta Subunit, Human; D000509:alpha-Fetoproteins; D001761:Bleomycin; D005047:Etoposide; D007770:L-Lactate Dehydrogenase; D002945:Cisplatin
vernacular_title: Attuale orientamento terapeutico nei tumori germinali del testicolo.