Postoperative ionizing radiation in the management of heterotopic bone formation in the temporomandibular joint.
OBJECTIVE
The purpose of this study was to evaluate the effectiveness and possible morbidity of postoperative low-dose ionizing radiation in the treatment of recurrent temporomandibular joint ankylosis.


METHODS
From 1987 to 1996, 14 patients with a history of multiple surgeries and recurrent temporomandibular joint ankylosis were treated postsurgically with radiation therapy. The treatment regimen initially selected was a postoperative dose of 2,000 rads in 10 fractions. Subsequently, 1,000 rads was found to be as effective. The success of therapy was assessed by means of serial radiographic studies and clinical examination, with the longest follow-up being 9 years.


RESULTS
Thirteen of 14 patients (93%) showed radiographic evidence of decreased heterotopic bone formation. No patient redeveloped ankylosis. A transient xerostomia appeared to be the only significant complication.


CONCLUSIONS
Low-dose ionizing radiation therapy, consisting of 1,000 rads given in five fractionated doses soon after surgical treatment, reduces recurrent heterotopic bone formation and appears to be a useful adjunct to the surgical management of temporomandibular joint ankylosis.
Reid
R
R
Department of Oral and Maxillofacial Surgery, The University of Texas at Houston, Health Science Center, 77030, USA.
Cooke
H
H
D000328:Adult; D000844:Ankylosis / Q000532:radiotherapy / Q000601:surgery; D019583:Dose Fractionation, Radiation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000532:radiotherapy* / Q000601:surgery; D011182:Postoperative Care; D018714:Radiotherapy, Adjuvant; D012008:Recurrence; D013704:Temporomandibular Joint / Q000601:surgery; D013705:Temporomandibular Joint Disorders / Q000532:radiotherapy* / Q000601:surgery; D013997:Time Factors