Iodanthine, a pyrrolizidine alkaloid from senecio iodanthus and senecio bracteatus
A phytochemical study of Senecio iodanthus and Senecio bracteatus afforded the new pyrrolizidine alkaloid iodanthine (3) in addition to the four known alkaloids retroisosenine (1), bulgarsenine (2), mulgediifoliine (4), and (12S)-12-hydroxyretroisosenine (6). The structure and absolute stereochemistry of the new compound (3) were determined by its spectral properties and confirmed by an X-ray diffraction analysis.
P rez-Castorena AL
Instituto de Quimica, Universidad Nacional Autonoma de Mexico, Circuito Exterior, Ciudad Universitaria, Coyoacan 04510, D.F., and Instituto de Biologia, Universidad Nacional Autonoma de Mexico, Circuito Exterior, Ciudad Universitaria, Coyoa.
Arciniegas
A
P rez R
Gutierrez
H
Toscano
RA
Villasenor
JL
Romo de Vivar A