title: Lymph node dissection for gastric cancer.
abstract: Complete tumor removal with margins of clearance at the resection lines must be the aim of today's surgical treatment of gastric cancer, and this must be applied even in lymph node dissection. But, over the last few decades, the extent and impact of lymphadenectomy remains controversial. Whereas Japanese centers advocate extensive lymph node dissection as the base of their excellent results, many Western surgeons, supported by actual randomized trials, believe that the potential benefit of such procedures cannot outweigh the risk of increased postoperative morbidity and mortality. However, if lymphadenectomy is restricted to the removal of nodes only, it does not influence the operative risk. Further, the lymph node ratio and number of lymph nodes involved are relevant prognostic parameters. Survival improvement can be achieved in a moderate degree of metastatic involvement of the nodes (pN0,1). Therefore, systematic lymph node dissection should be an integral part of the curative resection sought. Limited or no lymphadenectomy might be indicated in noncurative surgery or in special types of mucosal early gastric cancer, respectively.
authors.affiliation: Klinik für Allgemein- und Visceralchirurgie, Städtisches Klinikum Solingen, Solingen, Germany.
authors.forename: H J
authors.initials: HJ
authors.lastname: Meyer
authors.forename: J
authors.initials: J
authors.lastname: Jähne
mesh_terms: D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects / Q000145:classification / Q000379:methods; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D012189:Retrospective Studies; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000601:surgery*; D015996:Survival Rate