title: Lab-scale production unit design for nanosuspensions of sparingly soluble cytotoxic drugs.
abstract: Cytotoxic agent processing assumes certain prerequisites in order to guarantee a high level of security for both personnel and the material used. A lab-scale unit designed for the production and analysis of nanosuspensions of cytotoxic agents has been in use for more than three years. This design encompasses equipment, exhaust systems, materials used and measures for staff security, and this lab suite may also be used in applications that involve production in aseptic conditions.
authors.affiliation: Free University of Berlin, Institute of Pharmacy, Pharmaceutical Technology, Biotechnology and Biopharmaceutics, Kelchstr. 31, D-12169 Berlin, Germany.
authors.initials: BH
authors.lastname: Böhm
authors.initials: RH
authors.lastname: Müller