[The histamine and serotonin levels in the blood plasma of diabetic patients].
Fluorometry was done in 52 patients with diabetes mellitus to determine the blood plasma content of free histamine and free serotonin. The control group was 29 essentially healthy subjects. Significant increase was found out in free histamine during the stage of decompensation of diabetes mellitus (P < 0.01). With compensation of diabetes mellitus setting in, the content of histamine returns to normal (P < 0.01). The blood plasma level of free histamine can be used as an additional criterion in the assessment of compensation of diabetes mellitus. Free histamine is supposed to play an active part in the pathogenesis of diabetic angiopathies.
Shvets
N V
NV
Vydyborets
S V
SV
Gaĭdukova
S N
SN
Kramarenko
L D
LD
D000328:Adult; D000375:Aging / Q000097:blood; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000150:complications / Q000628:therapy; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications / Q000628:therapy; D005260:Female; D005470:Fluorometry; D006632:Histamine / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012701:Serotonin / Q000097:blood*; D012727:Sex Characteristics
D012701:Serotonin; D006632:Histamine
Soderzhanie gistamina i serotonina v plazme krovi bol'nykh sakharnym diabetom.