Screening for coeliac disease in women with a history of recurrent miscarriage or infertility.
Because subclinical coeliac disease may decrease fertility or complicate pregnancy, we screened women with recurrent miscarriage of unknown aetiology (n = 63), unexplained infertility (n = 47) and infertility with a known cause (n = 82), for anti-endomysium antibodies in serum to find undiagnosed coeliac disease. One woman (1-6%) with recurrent miscarriage, another woman (2.1%) with unexplained infertility and one woman (2.0%) in the control group (n = 51), were considered to have coeliac disease. We could not demonstrate a higher frequency of coeliac disease in women with infertility or recurrent miscarriage, but suggest that undiagnosed coeliac disease is common in women.
Kolho
K L
KL
Hospital for Children and Adolescents, Helsinki University Central Hospital, Finland.
Tiitinen
A
A
Tulppala
M
M
Unkila-Kallio
L
L
Savilahti
E
E
D000026:Abortion, Habitual / Q000209:etiology*; D000328:Adult; D001323:Autoantibodies / Q000097:blood; D002446:Celiac Disease / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007247:Infertility, Female / Q000209:etiology*; D008403:Mass Screening / Q000379:methods; D018485:Muscle Fibers, Skeletal / Q000276:immunology; D011247:Pregnancy
D001323:Autoantibodies; D007070:Immunoglobulin A