title: [Malignant phyllodes tumor with liposarcomatous differentiation. Description of a clinical case].
abstract: Sarcoma of the breast are a rare group of neoplasms representing less than 5% of Soft Tissue Sarcomas (STS). Between 1980 and 1995 in the National Institute foe Cancer Research (IST) of Genoa, 2188 patients were submitted to surgery for breast cancer. Seven of them were found to be affected by sarcoma, confirmed by histologic diagnosis. All the patients were between 39 and 87 years-old. Surgical treatments were: wide excision (1 case), total mastectomy (2 cases), radical mastectomy following Halsted (4 cases). A case of a 53 year-old woman with a phyllodes tumor initially transforming in to liposarcoma is reported. The patient was submitted to surgery (total mastectomy) and nowadays is alive and free of disease after 29 months. All authors agree that the treatment for sarcoma of the breast is early and complete surgical excision of the mass. The role of chemotherapy and radiotherapy is still uncertain. Outcome is based on histologic type, degree of differentiation and tumor size.
authors.affiliation: Divisione di Oncologia Chirurgica, Istituto per la Ricerca sul Cancro, Genova.
authors.forename: M
authors.initials: M
authors.lastname: Scala
authors.forename: P
authors.initials: P
authors.lastname: Mereu
authors.forename: D
authors.initials: D
authors.lastname: Comandini
authors.forename: L
authors.initials: L
authors.lastname: Nocentini
authors.forename: C
authors.initials: C
authors.lastname: Vecchio
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D018450:Disease Progression; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008080:Liposarcoma / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D015413:Mastectomy, Simple; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D003557:Phyllodes Tumor / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery
vernacular_title: Tumore filloide maligno con differenziazione liposarcomatosa. Descrizione di un caso clinico.