title: Primary cutaneous marginal zone B-cell lymphoma: a report of 9 cases.
abstract: BACKGROUND
  Primary cutaneous B-cell lymphoma is a heterogeneous group among which marginal zone B-cell lymphoma (MZL) appears to be the most common subtype.
  
  
  OBJECTIVE
  We analyze clinical presentation, histologic aspects, and outcome of patients with primary cutaneous MZL.
  
  
  METHODS
  All samples classified as primary cutaneous lymphoma over the past 10 years were reviewed, and cases of primary MZL were identified.
  
  
  RESULTS
  Nine cases of MZL were analyzed, all from the upper body region, with a predominance in elderly women. Histologic aspects included a dense, nodular, deep-seated infiltrate containing various proportions of small cells displaying a centrocyte-like, plasmacytoid or monocytoid appearance. Surface expression of CD5, CD10, and CD23 was negative. Long survival was noted but relapses in the skin, nodes, orbit, salivary glands, and breast were observed.
  
  
  CONCLUSIONS
  MZL is the predominant primary cutaneous lymphoma of our study. It has distinctive histologic and clinical features as well as outcome.
authors.affiliation: Service d'Anatomie-Pathologique, Hôpital Edouard-Herriot, 69437 Lyon Cedex 3, France.
authors.forename: A
authors.initials: A
authors.lastname: de la Fouchardière
authors.forename: B
authors.initials: B
authors.lastname: Balme
authors.forename: B
authors.initials: B
authors.lastname: Chouvet
authors.forename: C
authors.initials: C
authors.lastname: Sebban
authors.forename: H
authors.initials: H
authors.lastname: Perrot
authors.forename: A
authors.initials: A
authors.lastname: Claudy
authors.forename: P A
authors.initials: PA
authors.lastname: Bryon
authors.forename: B
authors.initials: B
authors.lastname: Coiffier
authors.forename: F
authors.initials: F
authors.lastname: Berger
mesh_terms: D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy