[The pharmacodynamic and pharmacokinetic characteristics of furosemide and furesis].
The object of the work was comparative study of the special features of the pharmacodynamic and pharmacokinetic properties of the diuretics furosemide and furesis in an ambulant regimen with the subject lying in an antiorthostatic position. Six practically healthy males were examined. They were given per os either 40 mg furosemide or one tablet of furesis (49 mg furosemide and 50 mg triamterine). Blood from the vein and urine were repeatedly tested.
Noskov
V B
VB
Central Research Center, Institute of Medico-Biological Problems, Moscow, Russia.
Goncharov
I B
IB
Kovachevich
I V
IV
Kodratenko
S N
SN
Starodubtsev
A K
AK
Sokolova
E V
EV
D000328:Adult; D004231:Diuresis / Q000187:drug effects; D004232:Diuretics / Q000032:analysis / Q000493:pharmacokinetics / Q000494:pharmacology*; D004338:Drug Combinations; D005665:Furosemide / Q000032:analysis / Q000493:pharmacokinetics / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011187:Posture / Q000502:physiology; D013607:Tablets; D013997:Time Factors; D014223:Triamterene / Q000032:analysis / Q000493:pharmacokinetics / Q000494:pharmacology*
D004232:Diuretics; D004338:Drug Combinations; D013607:Tablets; C041760:furotriam; D005665:Furosemide; D014223:Triamterene
Osobennosti farmakodinamiki i farmakokinetiki furosemida i furezisa.