The effect on performance and biochemical parameters when soil was added to aflatoxin-contaminated poultry rations.
The effects of silty clay loam soil on the performance and biochemical parameters of chicks were investigated when the soil was added to aflatoxin B1 (AFB1)-contaminated diets. One hundred 14-d-old White Leghorn chicks were fed a control ration (clean corn), a low aflatoxin-contaminated ration (120 ng AFB1/g), a high aflatoxin-contaminated ration (700 ng AFB1/g), or high aflatoxin-contaminated rations (700 ng AFB1/g) +10% or 25% soil. Body weight, feed consumption and blood samples were monitored weekly. Decreased feed consumption, body weight gain and efficiency of feed utilization, increased SGOT and LDH activities, and cholesterol and triglyceride concentrations, and decreased uric acid concentrations and ALP activity were observed in the chicks fed the high aflatoxin-contaminated ration without soil. Hepatomegaly was prominent in chicks fed the high aflatoxin-contaminated ration without soil, and some livers had extensive hepatocyte vacuolation, hepatocellular swelling, fatty change and hydropic degeneration, and stained positive for fat accumulation. Addition of soil reduced the detrimental effects of AFB1 for some parameters, although the reduction was less when 10% soil was fed compared with the 25% soil feeding.
Madden
U A
UA
Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Iowa State University, Ames 50011, USA.
Stahr
H M
HM
Stino
F K
FK
D016604:Aflatoxin B1 / Q000493:pharmacokinetics / Q000633:toxicity*; D000821:Animal Feed; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002273:Carcinogens / Q000493:pharmacokinetics / Q000633:toxicity*; D002645:Chickens / Q000378:metabolism*; D004435:Eating / Q000187:drug effects; D012987:Soil
D002273:Carcinogens; D012987:Soil; D016604:Aflatoxin B1