title: [Protective activity of 28-kDa 1-Cys peroxiredoxin determines its peroxidase activity].
abstract: The 28 kDa peroxiredoxin from rat exhibited peroxidase activity only in the presence of dithiothreitol. Both organic and nonorganic peroxidases were found to be substrates for the 28-kDa peroxiredoxin activity. Analysis of the protective antioxidant activity of the 28-kDa peroxiredoxin revealed that it is accounted for by its peroxidase activity.
authors.affiliation: Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia.
authors.forename: V I
authors.initials: VI
authors.lastname: Novoselov
authors.forename: I V
authors.initials: IV
authors.lastname: Peshenko
authors.forename: S V
authors.initials: SV
authors.lastname: Novoselov
authors.forename: S S
authors.initials: SS
authors.lastname: Kamzalov
authors.forename: M F
authors.initials: MF
authors.lastname: Bystrova
authors.forename: V A
authors.initials: VA
authors.lastname: Evdokimov
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Nikolaev
authors.forename: E E
authors.initials: EE
authors.lastname: Fesenko
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D004229:Dithiothreitol / Q000378:metabolism; D010544:Peroxidases / Q000378:metabolism*; D054464:Peroxiredoxins; D051381:Rats; D013379:Substrate Specificity
chemical_list: D000975:Antioxidants; D010544:Peroxidases; D054464:Peroxiredoxins; D004229:Dithiothreitol
vernacular_title: Protektornaia aktivnost' 28 1-cys peroksiredoksina opredeliaetsia ego peroksidaznoĭ aktivnost'iu.