Biochemical and genetic characterisation shows that the BRCA1 IVS20 insertion is a polymorphism.
Scholl
T
T
Pyne
M T
MT
Ward
B
B
Pruss
D
D
D000328:Adult; D000483:Alleles; D019313:BRCA1 Protein / Q000235:genetics*; D024682:BRCA2 Protein; D001943:Breast Neoplasms / Q000235:genetics*; D005260:Female; D006579:Heterozygote; D006801:Humans; D016254:Mutagenesis, Insertional; D009363:Neoplasm Proteins / Q000235:genetics; D011110:Polymorphism, Genetic; D012313:RNA / Q000737:chemistry; D017421:Sequence Analysis; D014157:Transcription Factors / Q000235:genetics
D019313:BRCA1 Protein; D024682:BRCA2 Protein; D009363:Neoplasm Proteins; D014157:Transcription Factors; D012313:RNA