title: Differential association of HIV-related neuropsychological impairment with semantic versus repetition priming.
abstract: There is evidence that the facilitating effects of stimulus repetition (repetition or identity priming) are mediated by visuoperceptual functions local to extrastriate cortex. Semantic or verbal-associative priming, on the other hand, is believed to be a function of more anterior brain systems. The present study finds evidence for disrupted semantic priming with intact repetition priming in a cognitively impaired HIV+ sample. These results are consistent with recent brain-imaging evidence for a subcortical and white-matter locus for HIV associated neuropathology resulting in effects on subcortical-frontal systems.
authors.affiliation: Department of Psychiatry, University of California San Francisco, USA.
authors.forename: P
authors.initials: P
authors.lastname: Jasiukaitis
authors.forename: G
authors.initials: G
authors.lastname: Fein
mesh_terms: D000328:Adult; D002540:Cerebral Cortex / Q000503:physiopathology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D009483:Neuropsychological Tests; D010775:Photic Stimulation; D011930:Reaction Time; D012660:Semantics; D013060:Speech / Q000502:physiology*