Functional genomics.
Complete genome sequences are providing a framework to allow the investigation of biological processes by the use of comprehensive approaches. Genome analysis also is having a dramatic impact on medicine through its identification of genes and mutations involved in disease and the elucidation of entire microbial gene sets. Studies of the sequences of model organisms, such as that of the nematode worm Caenorhabditis elegans, are providing extraordinary insights into development and differentiation that aid the study of these processes in humans. The field of functional genomics seeks to devise and apply technologies that take advantage of the growing body of sequence information to analyze the full complement of genes and proteins encoded by an organism.
Fields
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Howard Hughes Medical Institute, Departments of Genetics and Medicine, University of Washington, Box 357360, Seattle, WA 98195, USA. fields@u.washington.edu
Kohara
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Y
Lockhart
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DJ
D000818:Animals; D002107:Caenorhabditis / Q000235:genetics; D004247:DNA / Q000235:genetics; D005823:Genetics / Q000639:trends*; D015894:Genome, Human; D015698:Genomic Library; D006801:Humans; D011506:Proteins / Q000235:genetics; D012313:RNA / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000235:genetics
D011506:Proteins; D012313:RNA; D004247:DNA