title: [Genetic factors and colorectal cancer: a new approach to clinical experimentation].
abstract: The Authors point out the basis for a better characterisation of colo-rectal cancer and precursory lesions. In fact the etiology of familial adenomatous polyposis (FAP), aberrant crypt foci (ACF), hereditary non polyposis colon cancer syndrome (HNPCC) seems to be correlated to molecular pathology. Therefore the Authors review colo-rectal cancer natural history which frequently appears to be not related to clinical evolution.
authors.affiliation: Dipartimento di Scienze Chirurgiche e Tecnologie Mediche Applicate, Università degli Studi La Sapienza, Roma.
authors.forename: G
authors.initials: G
authors.lastname: Midiri
authors.forename: A
authors.initials: A
authors.lastname: Tesoriere
authors.forename: E
authors.initials: E
authors.lastname: Giarnieri
authors.forename: F
authors.initials: F
authors.lastname: Consorti
authors.forename: A
authors.initials: A
authors.lastname: Covotta
authors.forename: A
authors.initials: A
authors.lastname: Lorenzotti
authors.forename: V
authors.initials: V
authors.lastname: Urbano
authors.forename: L
authors.initials: L
authors.lastname: Luzzatto
authors.forename: A
authors.initials: A
authors.lastname: Bertolotti
authors.forename: A
authors.initials: A
authors.lastname: Vecchione
mesh_terms: D015179:Colorectal Neoplasms / Q000235:genetics* / Q000473:pathology; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000235:genetics* / Q000473:pathology; D016163:Genes, DCC / Q000235:genetics; D017431:Genes, MCC / Q000235:genetics; D006801:Humans; D008967:Molecular Biology; D012106:Research
vernacular_title: Fattori genetici e cancro del colon-retto: una nuova frontiera per la sperimentazione clinica.