Infection due to Absidia corymbifera in a patient with a massive crush trauma of the foot.
We report the case of a patient with a massive crushing trauma of the right foot who developed a local infection due to Absidia corymbifera. Systemic and local antifungal therapy with ketoconazole associated with hyperbaric oxygen therapy (HBO) yielded a rapid clinical and microbiological resolution. Controlled clinical studies are warranted to further elucidate the potential utility of HBO/antifungal combination therapy.
Scalise
A
A
Clinica di Chirurgia Plastica e Ricostruttiva Università degli Studi di Ancona, Italy.
Barchiesi
F
F
Viviani
M A
MA
Arzeni
D
D
Bertani
A
A
Scalise
G
G
D020095:Absidia / Q000187:drug effects / Q000302:isolation & purification*; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D018409:Foot Injuries / Q000150:complications*; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008826:Microbial Sensitivity Tests; D009091:Mucormycosis / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D016896:Treatment Outcome
D000935:Antifungal Agents