title: cis-Dihydroxylation of Olefins by a Non-Heme Iron Catalyst: A Functional Model for Rieske Dioxygenases.
abstract: The first iron complex capable of olefin cis-dihydroxylation in combination with H(2)O(2) provides a functional model for Rieske dioxygenases. Mechanistic studies on the model reaction suggest the participation of an Fe(III)(eta(2)-OOH) intermediate, with the oxygen atoms coming exclusively from H(2)O(2) (see reaction scheme; L denotes a tris(6-methyl-2-pyridylmethyl)amine ligand, Solv=solvent). The similarities between the model and the enzymes strengthen the proposal that an Fe(III)-peroxo intermediate is involved in the enzymatic reactions.
authors.affiliation: Department of Chemistry and Center for Metals in Biocatalysis, University of Minnesota, Minneapolis, MN 55455 (USA).
authors.initials: K
authors.lastname: Chen
authors.lastname: Que Jr