title: Validation of diet composition for the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group.
abstract: The Dietary Approaches to Stop Hypertension trial involved 4 clinical sites at which 459 participants (in 5 cohorts) were fed 3 dietary patterns over 11 weeks per cohort. The 3 patterns were a control diet, a fruits and vegetables diet, and a combination diet. Before the intervention, key nutrient levels in each diet were validated at 2 energy levels (2,100 and 3,100 kcal) by chemical analysis of the prepared menus. During intervention, diets were sampled across all cohorts, sites, and energy levels, and 7-day menu cycle composites were assayed. In general, sodium, potassium, calcium, and magnesium in the validated menus for each diet/energy level met the nutrient targets, though moderate variability was evident among individual menus, particularly for potassium, calcium, and magnesium. However, as intended, there was clear separation and no overlap in mineral levels in individual menus of diets that were designed to differ. During intervention, macronutrient contents met nutrient goals. Sodium, potassium, calcium, and magnesium in the diets generally met target levels, though potassium in the fruits and vegetables diet was 11% to 23% below target. There were no consistent differences in nutrient levels between sites. The mean nutrient levels in the validated menus and diets sampled during intervention were in excellent agreement with each other, though sodium was somewhat higher (approximately 6%) in the diets from intervention vs validation. These results indicate the success of the quality control measures implemented and suggested consistent overall diet composition throughout the 28 months during which the study was conducted.
authors.affiliation: Virginia Polytechnic Institute and State University, Blacksburg 24061-0308, USA.
authors.forename: K M
authors.initials: KM
authors.lastname: Phillips
authors.forename: K K
authors.initials: KK
authors.lastname: Stewart
authors.forename: N M
authors.initials: NM
authors.lastname: Karanja
authors.forename: M M
authors.initials: MM
authors.lastname: Windhauser
authors.forename: C M
authors.initials: CM
authors.lastname: Champagne
authors.forename: J F
authors.initials: JF
authors.lastname: Swain
authors.forename: P H
authors.initials: PH
authors.lastname: Lin
authors.forename: M A
authors.initials: MA
authors.lastname: Evans
mesh_terms: D001794:Blood Pressure; D004032:Diet; D006801:Humans; D006973:Hypertension / Q000178:diet therapy*; D015337:Multicenter Studies as Topic; D009747:Nutritional Physiological Phenomena; D011786:Quality Control; D016032:Randomized Controlled Trials as Topic