title: In vivo proton MR spectroscopy of untreated and treated brain abscesses.
abstract: MR spectroscopy was performed in three patients with brain abscesses. In two patients, MR spectroscopy revealed end-products of bacterial breakdown (acetate, succinate, amino acids, lactate) in the abscess cysts. In one of these, the spectrum was reversed to a single lactate peak after treatment. In the third patient, MR spectroscopy was performed only after treatment and showed a single nonspecific lactate peak. MR spectroscopy is a potential tool for noninvasive diagnosis of brain abscess and might be useful for evaluating changes after treatment.
authors.affiliation: Department of Radiology, University Hospital, Lund, Sweden.
authors.forename: I M
authors.initials: IM
authors.lastname: Burtscher
authors.forename: S
authors.initials: S
authors.lastname: Holtås
mesh_terms: D000368:Aged; D000596:Amino Acids / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001922:Brain Abscess / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism / Q000601:surgery; D003560:Cysts / Q000175:diagnosis / Q000378:metabolism; D006801:Humans; D019344:Lactic Acid / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged
chemical_list: D000596:Amino Acids; D000900:Anti-Bacterial Agents; D019344:Lactic Acid