Neural mechanisms underlying amblyopia.
The nature of the neural basis of amblyopia is a matter of some debate. Recent neurophysiological data show correlates of amblyopia in the spatial properties of neurons in primary visual cortex. These neuronal deficits are probably the initial manifestation of the visual loss, but there are almost certainly additional deficits at higher levels of the visual pathways.
Kiorpes
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Center for Neural Science, 4 Washington Place, Room 809, New York University, New York, New York 10003, USA. lynne@cns.nyu.edu
McKee
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D000550:Amblyopia / Q000209:etiology / Q000503:physiopathology*; D000818:Animals; D015858:Anisometropia / Q000209:etiology / Q000503:physiopathology*; D015350:Contrast Sensitivity / Q000502:physiology*; D006801:Humans; D013285:Strabismus / Q000209:etiology / Q000503:physiopathology*; D014793:Visual Cortex / Q000502:physiology