Forensic toxicological implication of acute fatal poisoning cases due to benfuracarb ingestion.
We describe here three cases involving acute fatalities due to benfuracarb ingestion and the forensic toxicological implications. Benfuracarb, a carbamate insecticide and its main metabolite carbofuran, were detected using thin layer chromatography (TLC) and gas chromatography/mass spectrophotometry (GC/MS) after extraction with ethyl acetate and then quantified using gas chromatography (GC) equipped with NPD. The blood levels of benfuracarb and carbofuran were in the range of 0.30-2.32 microg/ml and 1.45-1.47 microg/ml, respectively. Benfuracarb was not detected in urine, but carbofuran was detected in the range of 0.53-2.66 microg/ml.
Lee
S K
SK
National Institute of Scientific Investigation, Seoul, Korea. nisi@shinbiro.com
Ameno
K
K
Yang
J Y
JY
In
S W
SW
Kim
K U
KU
Kwon
T J
TJ
Yoo
Y C
YC
Kubota
T
T
Ameno
S
S
Ijiri
I
I
D000328:Adult; D001572:Benzofurans / Q000032:analysis / Q000506:poisoning*; D002235:Carbofuran / Q000032:analysis; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007306:Insecticides / Q000032:analysis / Q000506:poisoning*; D008297:Male; D011041:Poisoning / Q000175:diagnosis*; D013405:Suicide / Q000331:legislation & jurisprudence*; D015091:beta-Alanine / Q000031:analogs & derivatives* / Q000032:analysis / Q000506:poisoning
D001572:Benzofurans; D007306:Insecticides; D015091:beta-Alanine; C096128:benfuracarb; D002235:Carbofuran