title: Spatial working memory in asymptomatic HIV-infected subjects.
abstract: Many clinical and research findings converge to indicate that frontal lobe, basal ganglia, and related neuronal connections are primarily involved in human immunodeficiency virus (HIV) infection; frontal lobe, mainly the prefrontal cortex, has a specialized role in working memory processes. This study focused on neuropsychological evaluation of the spatial component of working memory in a sample of 34 asymptomatic HIV-infected subjects as compared with 34 age- and sex-matched seronegative control subjects. A computer-administered test assessing spatial working memory was used for the neuropsychological evaluation. The findings did not show any spatial working memory impairment during the asymptomatic phase of HIV infection.
authors.affiliation: Psychiatric Branch, Centro San Luigi, University of Milan Medical School, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Grassi
authors.forename: G
authors.initials: G
authors.lastname: Garghentini
authors.forename: A
authors.initials: A
authors.lastname: Campana
authors.forename: E
authors.initials: E
authors.lastname: Grassi
authors.forename: S
authors.initials: S
authors.lastname: Bertelli
authors.forename: P
authors.initials: P
authors.lastname: Cinque
authors.forename: M
authors.initials: M
authors.lastname: Epifani
authors.forename: A
authors.initials: A
authors.lastname: Lazzarin
authors.forename: S
authors.initials: S
authors.lastname: Scarone
mesh_terms: D000328:Adult; D010054:Brief Psychiatric Rating Scale; D005260:Female; D005625:Frontal Lobe / Q000033:anatomy & histology / Q000503:physiopathology; D006679:HIV Seropositivity / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D009483:Neuropsychological Tests; D010468:Perceptual Disorders / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D012720:Severity of Illness Index; D013028:Space Perception / Q000502:physiology*; D011795:Surveys and Questionnaires