title: Ultrastructural differences observed in Paracoccidioides brasiliensis yeast phase cells grown on solid and in liquid medium.
abstract: An ultrastructural study was conducted on, yeast-like Paracoccidioides brasiliensis cells grown on liquid and solid peptone--yeast extract--glucose medium. A large proportion of cells grown in liquid medium presented cytoplasmic damage compared with the cells grown on solid medium, which remained intact, suggesting that agar plays an important role in the development of this fungus.
authors.affiliation: Departamento de Micologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
authors.forename: C de M
authors.initials: Cde M
authors.lastname: Borba
authors.forename: M de N
authors.initials: Mde N
authors.lastname: Meirelles
authors.forename: A M
authors.initials: AM
authors.lastname: da Silva
authors.forename: P C
authors.initials: PC
authors.lastname: de Oliveira
mesh_terms: D000362:Agar; D003470:Culture Media / Q000737:chemistry; D010228:Paracoccidioides / Q000254:growth & development / Q000648:ultrastructure*
chemical_list: D003470:Culture Media; D000362:Agar