title: Effect of antibiotics and anti-inflammatory agents on the purified protein derivative response in the rat.
abstract: We investigated the effects of several antibiotics and anti-inflammatory agents on the purified protein derivative (PPD) response in the rat. Animals were immunized with Mycobacterium bovis vaccine BCG. Antibiotics and anti-inflammatory drugs were administered at therapeutic doses for 10 d. Chloramphenicol, erythromycin, aspirin and ibuprofen suppressed the PPD response, but penicillin and acetaminophen had no significant effects.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Firat University, Elazig, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Kabakuş
authors.forename: A
authors.initials: A
authors.lastname: Kalkan
authors.forename: S
authors.initials: S
authors.lastname: Felek
authors.forename: B
authors.initials: B
authors.lastname: Yilmaz
authors.forename: R
authors.initials: R
authors.lastname: Mogulkoç
authors.forename: A
authors.initials: A
authors.lastname: Baltaci
authors.forename: S S
authors.initials: SS
authors.lastname: Kiliç
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D001500:BCG Vaccine / Q000008:administration & dosage; D005188:False Negative Reactions; D005260:Female; D007114:Immunization; D051381:Rats; D017208:Rats, Wistar; D014373:Tuberculin / Q000276:immunology*; D014374:Tuberculin Test
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001500:BCG Vaccine; D014373:Tuberculin