[Assessment of coronary revascularization with 99mTC-sestamibi SPECT. Quantitative analysis of segmentary perfusion].
We analyzed the change in myocardial perfusion recovery after revascularization using Dipyridamole-99mTc-Sestamibi SPECT in 37 patients (mean age 59 years old; 33 males), all of whom had wall motion abnormalities and 84% who had myocardial infarction. The perfusion defects were evaluated before the revascularization and at 64 days of the angioplasty in 18 cases and of the coronary artery bypass graft (CABG) in 19 and were compared with a normal Dipyridamole database. The bullseye parameters were: decrease in severity, size and ischemia area of the defect and worsening of the defect. It was found that the defects decreased in an average of 31. 4% for extension and 35,8% for severity (with no significant differences between the 2 techniques); the ischemia was reduced in 75.7%. No new defects appeared although some presented a slight worsening. The net change in reduction was 26% for extension and 29% for severity.


CONCLUSIONS
In patients with a high prevalence of myocardial infarction, revascularization obtained a moderate decrease in the perfusion defects and a significant ischemia decrease.
Massardo Vega
T
T
Centro de Medicina Nuclear, Hospital Clínico Universidad de Chile, Santiago, 6531063, Chile. tmassardo@ns.hospital.uchile.cl
Jofré Manieu
M J
MJ
Muñoz Meynet
A
A
Hidalgo Garrido
P
P
Yovanovich Said
J
J
Humeres Aprá
P
P
Maiers Pardo
P
P
González Espinoza
P
P
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D002316:Cardiotonic Agents; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003627:Data Interpretation, Statistical; D004176:Dipyridamole; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
D002316:Cardiotonic Agents; D004176:Dipyridamole; D017256:Technetium Tc 99m Sestamibi
Evaluación de la revascularización coronaria con 99m Tc-sestamibi SPECT. Análisis cuantitativo de perfusión segmentaria.