title: Methemoglobinemia as an uncommon cause of cyanosis.
abstract: Cyanosis is usually caused by decreased arterial oxygen saturation due to pulmonary or cardiac diseases. Methemoglobinemia is a rare cause, sometimes with lethal outcome. Two patients are described, both with an unremarkable cardiopulmonary history, presented with severe cyanosis due to aniline-induced methemoglobinemia that developed at work. The symptoms and the treatment of methemoglobinemia are discussed.
authors.affiliation: Department of Internal Medicine, Drechtsteden Ziekenhuis, AK Dordrecht, The Netherlands.
authors.forename: H
authors.initials: H
authors.lastname: Demirel
authors.forename: V S
authors.initials: VS
authors.lastname: Koster
authors.forename: M J
authors.initials: MJ
authors.lastname: Koot
authors.forename: H H
authors.initials: HH
authors.lastname: Ponssen
authors.forename: A C
authors.initials: AC
authors.lastname: van Vliet
mesh_terms: D000328:Adult; D000814:Aniline Compounds / Q000506:poisoning*; D002318:Cardiovascular Diseases / Q000150:complications / Q000175:diagnosis; D003490:Cyanosis / Q000209:etiology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008487:Medical History Taking; D008708:Methemoglobinemia / Q000139:chemically induced* / Q000175:diagnosis* / Q000188:drug therapy; D008751:Methylene Blue / Q000627:therapeutic use; D008875:Middle Aged; D016877:Oxidants / Q000506:poisoning*; D016896:Treatment Outcome
chemical_list: D000814:Aniline Compounds; D016877:Oxidants; C023650:aniline; D008751:Methylene Blue