Purine based combinatorial chemistry: solution phase simultaneous addition of functionalities. Iterative deconvolution by orthogonal protection to a single compound with potent antibacterial activity.
Fraser
A S
AS
Department of Medicinal Chemistry, Isis Pharmaceuticals, Inc., Carlsbad, California 92008, USA.
Kawasaki
A M
AM
Cook
P D
PD
D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D011687:Purines / Q000737:chemistry* / Q000494:pharmacology
D000890:Anti-Infective Agents; D011687:Purines