title: Botox for hyperadduction of the false vocal folds: a case report.
abstract: We present a patient with severe hyperadduction of the false vocal folds (FVF) treated with Botulinum Toxin injections to each FVF. This patient presented with severe dysphonia and was found to demonstrate severe hyperadduction of the FVF's with all phonatory tasks. The patient was treated with extensive speech therapy without improvement in voice quality nor FVF motion pattern. He was then injected with Botox A bilaterally using a peroral approach to the FVFs. Shortly after treatment the patient experienced dramatic improvement in voice quality. Videolaryngoscopy revealed no adduction of the FVFs with phonation and essentially normal true vocal fold motion. He remained with normal voice quality one year after treatment without any further treatment. Possible mechanism of action of this type of treatment are discussed.
authors.affiliation: Department of Otolaryngology, University of Pittsburgh, School of Medicine, PA, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Rosen
authors.forename: T
authors.initials: T
authors.lastname: Murry
mesh_terms: D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D013070:Speech Therapy / Q000379:methods; D016896:Treatment Outcome; D014827:Vocal Cords / Q000503:physiopathology*; D014832:Voice Disorders / Q000503:physiopathology* / Q000628:therapy*
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A