Effect of body mass index and follicular synchrony in the ovarian response to ovulation induction with menotropins.
OBJECTIVE
To determine the correlation between body mass index, follicular synchrony, and pregnancy rate in a controlled ovarian hyperstimulation program with menotropins.


METHODS
Seventy-nine hyperstimulation cycles were evaluated. Transvaginal ultrasonographic control was performed and 10,000 IU of human chorionic gonadotropin were administered when the dominant follicle reached a diameter > 16 mm. In order to evaluate the follicular response, the ovarian synchrony factor was used (# follicles > or =16 mm/# follicles > 10 mm). For the statistical analysis, linear correlation and chi-square tests were used.


RESULTS
When patients had a normal body mass index there was a positive correlation ( r = .52) between body mass index (kg/m(1.5)) and the ovarian synchrony factor. Weight deficiency and obesity had a deleterious effect on the ovarian response ( r = -.47 and r = -.77, respectively). There was a significant difference in the number of pregnancies in patients with ideal weight in relationship to the subgroup with weight deficit.


CONCLUSIONS
An adequate body constitution increases the possibilities of achieving success in ovulation induction programs; on the other hand, weight disturbances have a deleterious effect on ovulation.
Kably-Ambe
A
A
Assisted Reproduction Unit, Clínica de Infertilidad-Endoscopia y Embarazo de Alto Riesgo, México, DF.
Barrón-Vallejo
J
J
Limón-Luque
L M
LM
D015992:Body Mass Index; D016009:Chi-Square Distribution; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use*; D005498:Follicular Phase / Q000187:drug effects; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy* / Q000209:etiology; D008596:Menotropins / Q000627:therapeutic use*; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D018873:Pregnancy Rate; D014463:Ultrasonography; D014621:Vagina / Q000000981:diagnostic imaging
D005300:Fertility Agents, Female; D008596:Menotropins