[Cellular sociological characteristics of osteoblasts].
There is a great hope to treat long bone defects with bioactive artificial bone constructed by osteoblasts and biomaterials, in which the key point is to provide an optimum environment for the normal function of osteoblasts. The cellular sociological characteristics of osteoblasts were summarized and it was suggested that the ideal bioactive artificial bone should be composed of inorganic and organic materials together with cellular components such as osteoblasts and vascular endothelial cells, and combined with control release of growth factors, following its implantation it could be vascularized very soon and merged with the host bone by bony consolidation.
Yu
X
X
Department of Orthopedic Surgery, First University Hospital, West China University of Medical Sciences, Chengdu, Sichuan, P.R. China.
Yang
Z
Z
Ma
J
J
D018786:Bone Substitutes; D002450:Cell Communication; D004730:Endothelium, Vascular / Q000502:physiology; D005109:Extracellular Matrix; D006801:Humans; D016348:Osseointegration; D010006:Osteoblasts / Q000502:physiology*; D010010:Osteoclasts / Q000502:physiology
D018786:Bone Substitutes