Course of postoperative inflammation after implantation of 4 types of foldable intraocular lenses.
OBJECTIVE
To compare the course of postoperative inflammation after small incision cataract surgery with implantation of 4 types of foldable intraocular lenses (IOLs).


METHODS
Department of Ophthalmology, University Hospital of Vienna, Austria.


METHODS
One hundred twenty eyes were prospectively randomized to receive a foldable silicone (Pharmacia 920), hydrogel (Bausch & Lomb Hydroview), methyl methacrylate/hydroxyethyl methacrylate (Mentor MemoryLens), or acrylic (Alcon AcrySof) IOL. All surgery was performed by the same experienced surgeon using a standardized surgical protocol: clear corneal incision, capsulorhexis, phacoemulsification, and in-the-bag implantation of the IOL. All patients received standardized postoperative medication and follow-up. Postoperative inflammation was evaluated by measuring aqueous flare preoperatively and 1, 3, 7, 14, 28, 90, and 180 days after surgery using the Kowa 1000 laser flare-cell meter.


RESULTS
Except on the first day after surgery, when the AcrySof group had higher flare values than the other groups (P = .0265), no significant differences were found up to 6 months. Re-establishment of the blood-aqueous barrier was similar in eyes with the AcrySof, Hydroview, and MemoryLens IOLs; the course of postoperative inflammation was different in eyes with the silicone IOL.


CONCLUSIONS
Comparison of postoperative flare values after implantation of 4 foldable IOLs showed no clinically relevant differences in the course of postoperative inflammation.
Schauersberger
J
J
Department of Ophthalmology, University Hospital of Vienna, Austria.
Kruger
A
A
Abela
C
C
Müllner-Eidenböck
A
A
Petternel
V
V
Svolba
G
G
Amon
M
M
D000180:Acrylic Resins; D000368:Aged; D018916:Blood-Aqueous Barrier; D005260:Female; D005549:Foreign-Body Reaction / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008297:Male; D019904:Polymethyl Methacrylate; D011183:Postoperative Complications / Q000503:physiopathology; D011446:Prospective Studies; D012826:Silicone Elastomers; D013997:Time Factors; D014606:Uveitis, Anterior / Q000209:etiology* / Q000503:physiopathology
D000180:Acrylic Resins; D012826:Silicone Elastomers; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D019904:Polymethyl Methacrylate