title: Forensic toxicological implication of acute fatal poisoning cases due to benfuracarb ingestion.
abstract: We describe here three cases involving acute fatalities due to benfuracarb ingestion and the forensic toxicological implications. Benfuracarb, a carbamate insecticide and its main metabolite carbofuran, were detected using thin layer chromatography (TLC) and gas chromatography/mass spectrophotometry (GC/MS) after extraction with ethyl acetate and then quantified using gas chromatography (GC) equipped with NPD. The blood levels of benfuracarb and carbofuran were in the range of 0.30-2.32 microg/ml and 1.45-1.47 microg/ml, respectively. Benfuracarb was not detected in urine, but carbofuran was detected in the range of 0.53-2.66 microg/ml.
authors.affiliation: National Institute of Scientific Investigation, Seoul, Korea. nisi@shinbiro.com
authors.forename: S K
authors.initials: SK
authors.lastname: Lee
authors.forename: K
authors.initials: K
authors.lastname: Ameno
authors.forename: J Y
authors.initials: JY
authors.lastname: Yang
authors.forename: S W
authors.initials: SW
authors.lastname: In
authors.forename: K U
authors.initials: KU
authors.lastname: Kim
authors.forename: T J
authors.initials: TJ
authors.lastname: Kwon
authors.forename: Y C
authors.initials: YC
authors.lastname: Yoo
authors.forename: T
authors.initials: T
authors.lastname: Kubota
authors.forename: S
authors.initials: S
authors.lastname: Ameno
authors.forename: I
authors.initials: I
authors.lastname: Ijiri
mesh_terms: D000328:Adult; D001572:Benzofurans / Q000032:analysis / Q000506:poisoning*; D002235:Carbofuran / Q000032:analysis; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007306:Insecticides / Q000032:analysis / Q000506:poisoning*; D008297:Male; D011041:Poisoning / Q000175:diagnosis*; D013405:Suicide / Q000331:legislation & jurisprudence*; D015091:beta-Alanine / Q000031:analogs & derivatives* / Q000032:analysis / Q000506:poisoning
chemical_list: D001572:Benzofurans; D007306:Insecticides; D015091:beta-Alanine; C096128:benfuracarb; D002235:Carbofuran