title: Effect of verbascoside on decreasing concentration of oxygen free radicals and lipid peroxidation in skeletal muscle.
abstract: OBJECTIVE
  To detect the effects of verbascoside on decreasing the concentration of oxygen free radicals (OFR) and lipid peroxidation in skeletal muscle resulting from exhaustive exercise.
  
  
  METHODS
  Electron spin resonance (ESR) technique and thiobarbituric acid reaction (TBAR) method were used to detect the concentration of OFR in intact gastrocnemius muscle and the contents of milondialdehyde (MDA) in muscle homogenate.
  
  
  RESULTS
  Verbascoside decreased the concentration of OFR (P < 0.05) and the level of lipid peroxidation (P < 0.05) in muscle caused by exercise.
  
  
  CONCLUSIONS
  Verbascoside has the effects of reducing oxidative stress in muscle caused by exhaustive exercise by decreasing the concentration of free radicals and the level of lipid peroxidation.
authors.affiliation: Department of Orthopedics & Traumatology, Chinese University of Hong Kong, China. lijx@HKSDB.ORG.HK
authors.forename: J X
authors.initials: JX
authors.lastname: Li
authors.forename: D
authors.initials: D
authors.lastname: Xin
authors.forename: H
authors.initials: H
authors.lastname: Li
authors.forename: J F
authors.initials: JF
authors.lastname: Lu
authors.forename: C W
authors.initials: CW
authors.lastname: Tong
authors.forename: J N
authors.initials: JN
authors.lastname: Gao
authors.forename: K M
authors.initials: KM
authors.lastname: Chan
mesh_terms: D000818:Animals; D016166:Free Radical Scavengers / Q000494:pharmacology*; D005609:Free Radicals; D005960:Glucosides / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D018482:Muscle, Skeletal / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*; D010636:Phenols; D005082:Physical Exertion; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D059808:Polyphenols
chemical_list: D016166:Free Radical Scavengers; D005609:Free Radicals; D005960:Glucosides; D008315:Malondialdehyde; D010100:Oxygen; D010636:Phenols; C058956:acteoside; D059808:Polyphenols