Antibody response to P. aeruginosa in patients with cystic fibrosis: evaluation of two methods.
The immunological response to Ps. aeruginosa antigens may be a sensitive and early indicator of the colonisation of the lungs with these organisms in patients with cystic fibrosis. This study used an immunoenzymatic system and immunoblotting to evaluate the antibody response of 20 patients without apparent Ps. aeruginosa lung infection. These was an agreement in the results obtained with the two methods in 87.5% of cases.
Magni
A
A
Institute of Microbiology, University La Sapienza Rome, Italy.
Giordano
A
A
Trancassini
M
M
Graziani
C
C
De Vito
D
D
Antonelli
M
M
Cipriani
P
P
D000907:Antibodies, Bacterial / Q000097:blood*; D003550:Cystic Fibrosis / Q000150:complications*; D005069:Evaluation Studies as Topic; D006801:Humans; D015151:Immunoblotting; D007124:Immunoenzyme Techniques; D008171:Lung Diseases / Q000175:diagnosis* / Q000276:immunology; D011552:Pseudomonas Infections / Q000175:diagnosis* / Q000276:immunology
D000907:Antibodies, Bacterial