title: [Successful treatment of a right atrial thrombus secondary to central venous catheterization].
abstract: The authors report on the thrombolytic therapy in an infant born after 36 weeks of gestation weighing 2800 grams. She was repeatedly operated on for intestinal perforation and a right atrial thrombus developed as a complication of the central venous catheterisation. Complete dissolution of the thrombus was observed after 5 days of local urokinase infusion (initial dose: 3000 IU/kg/hr, gradually elevated up to 4500 IU/kg/hr) through an Epicutaneocava catheter positioned in the right atrium. Subsequently, prophylactic intravenous heparin infusion (100 IU/kg/hr), then subcutaneous low-molecular-weight heparin (2 x 100 AXa IU/kg/day) was given. No side effects of the treatment was observed. On follow-up examinations at the age of 5 months the infant proved to be healthy.
authors.affiliation: Pécsi Orvostudományi Egyetem Gyermekklinika.
authors.forename: K
authors.initials: K
authors.lastname: Adamovich
authors.forename: A
authors.initials: A
authors.lastname: Tárnok
authors.forename: E
authors.initials: E
authors.lastname: Szauer
mesh_terms: D002405:Catheterization, Central Venous / Q000009:adverse effects*; D005260:Female; D006325:Heart Atria / Q000473:pathology; D006801:Humans; D007081:Ileostomy; D007231:Infant, Newborn; D007416:Intestinal Perforation / Q000601:surgery*; D010960:Plasminogen Activators / Q000627:therapeutic use; D011183:Postoperative Complications; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology*; D016896:Treatment Outcome; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use
chemical_list: D010960:Plasminogen Activators; D014568:Urokinase-Type Plasminogen Activator
vernacular_title: Centrális vénás kanül szövödményeként kialakult jobb pitvari thrombus sikeres kezelése.