title: A new cyclic phosphoramidate D4T prodrug approach cycloAmb-D4T-phosphoramidates.
abstract: A new potential phosphoramidate prodrug approach for d4T 1 is described. In hydrolyses studies the cycloAmb-d4T-phosphoramidates 2 and 3 proved to deliver d4TMP following a tandem reaction.
authors.affiliation: Institut für Organische Chemie, Universität Hamburg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Lorey
authors.forename: C
authors.initials: C
authors.lastname: Meier
mesh_terms: D009943:Organophosphorus Compounds / Q000737:chemistry; D011355:Prodrugs / Q000737:chemistry*; D018119:Stavudine / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D009943:Organophosphorus Compounds; D011355:Prodrugs; D018119:Stavudine