title: [Nephro-urological monitoring technology based on radionuclide functional tests (tasks of an automated workplace)].
abstract: The paper deals with a diagnostic informational and analytical system (DIAS). The system is based on the current concept of a dynamic model of nephro-urological clearance macroregulation under retention factors at the pre-, intra-, and postrenal levels during drug load tests. DIAS includes a package of dynamic renoscintigraphic techniques, as well as original software support. A system for parameters of renal clearance regulation has been developed, which is effective at nephro-urological screening and monitoring at all treatment stages for cancer patients. A two-detector chamber which permits the mounting of a detector at an angle to the patient's body is the optimum diagnostic apparatus for a cancer clinic. The use of functional tests makes it possible to examine the regulatory reserves for each kidney, followed up by the choice of adequate corrective measures to prevent renal failure during treatment. In some cases, DIAS monitoring frequently shows a higher sensitivity to the signs of latent renal failure than does routine clinical and laboratory monitoring. The effective radiation dose taken by a patient during a study by the DIAS technology aimed at reducing radioopaque doses is 100-150 times higher than that at an X-ray study and is an order less than during routine urinary tests.
authors.forename: S G
authors.initials: SG
authors.lastname: Averinova
authors.forename: A V
authors.initials: AV
authors.lastname: Kashkadaeva
authors.forename: S V
authors.initials: SV
authors.lastname: Shiriaev
authors.forename: A M
authors.initials: AM
authors.lastname: Nechipaĭ
authors.forename: G D
authors.initials: GD
authors.lastname: Dmitrieva
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003936:Diagnosis, Computer-Assisted; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000502:physiology; D007674:Kidney Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D011877:Radionuclide Imaging; D017595:Renal Plasma Flow; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D012984:Software; D014553:Urinary Tract Physiological Phenomena; D014563:Urodynamics; D014565:Urogenital Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D009396:Wilms Tumor / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy
vernacular_title: Tekhnologiia nefrourologicheskogo kontrolia na baze radionuklidnykh funktsional'nykh testov (zadachi avtomatizirovannogo rabochego mesta).