title: Mobile carotid plaques: the natural history of two asymptomatic and non-operated cases.
abstract: We studied two cases of mobile internal carotid artery lesions in symptom-free patients. Both cases were diagnosed by means of routine carotid duplex ultrasound scanning, and neither patient was operated on. With medical therapy with oral anticoagulants, the two lesions spontaneously disappeared without any clinical sequel, and no evidence of infarcts was shown by means of repeated computed tomography brain scans. After uneventful 2- and 3-year follow-up periods, there was no evidence of recurrence. This is the first published data on asymptomatic mobile carotid lesions and their natural history that shows a benign course in a long-term follow-up period. We suggest that a non-surgical approach may be considered selectively in high-risk symptom-free patients who have mobile and floating internal carotid artery lesions.
authors.affiliation: Laboratory for Cardiovascular Investigation, Research Academic Surgical Unit, Imperial College School of Medicine, London W2, United Kingdom.
authors.forename: G
authors.initials: G
authors.lastname: Szendro
authors.forename: M M
authors.initials: MM
authors.lastname: Sabetai
authors.forename: T J
authors.initials: TJ
authors.lastname: Tegos
authors.forename: S
authors.initials: S
authors.lastname: Dhanjil
authors.forename: A F
authors.initials: AF
authors.lastname: Lennox
authors.forename: A N
authors.initials: AN
authors.lastname: Nicolaides
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D001161:Arteriosclerosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology*; D001921:Brain / Q000000981:diagnostic imaging; D002343:Carotid Artery, Internal; D016893:Carotid Stenosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D018616:Ultrasonography, Doppler, Duplex
chemical_list: D000925:Anticoagulants