Synthesis, characterization and antimicrobial studies of metal(II) bis-chelates and mixed-ligand complexes of alpha-(2-hydroxyphenyl)-N-(1-phenyl-2-nitroethyl)nitrone.
This paper describes the synthesis of complexes of the type MB2. 2H2O and CuBL.2H2O where BH = alpha-(2-hydroxyphenyl)-N-(1-phenyl-2-nitroethyl)-nitrone, M = copper(II)/cobalt(II)/nickel(II) and LH = salicylaldehyde/salicylaldoxime/8-hydroxyquinoline/2-hydroxypyridine. The magnetic moment, ligand field spectra, thermal and ESR studies reveals that these dihydrates possess octahedral geometry. The antimicrobial studies of these complexes against several microorganisms such as Staphylococcus aureus, Escherichia coli, Klebsiella aerogenes, Salmonella typhi and Pseudomonas sp. have been tested and reported in comparison with ceftazidime standard.
Thirumalaikumar
M
M
School of Chemistry, Madurai Kamaraj University, India.
Sivakolunthu
S
S
Muthusubramanian
S
S
Mohan
P
P
Sivasubramanian
S
S
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D008024:Ligands; D008826:Microbial Sensitivity Tests; D009589:Nitrogen Oxides / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D008024:Ligands; D009589:Nitrogen Oxides; C015388:nitrones