Acute neutrophilic dermatosis induced by all-trans-retinoic acid treatment for acute promyelocytic leukemia.
All-trans-retinoic acid (ATRA) is considered the recommended induction treatment for acute promyelocytic leukemia (APL). Although the dermatological side effects associated with ATRA treatment are relatively common, acute neutrophilic dermatosis (Sweet's syndrome) has only been rarely reported. We describe such a case who responded to chemotherapy and not to low doses of corticosteroids.
Levi
I
I
Institute of Hematology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Raanani
P
P
Shalmon
B
B
Schiby-Brilliant
R
R
Ben-Bassat
I
I
D000970:Antineoplastic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications / Q000188:drug therapy*; D008875:Middle Aged; D016463:Sweet Syndrome / Q000139:chemically induced*; D014212:Tretinoin / Q000009:adverse effects*
D000970:Antineoplastic Agents; D014212:Tretinoin