title: [What is the role of the correspondence of free PSA/total PSA in the staging of local prostate cancer? Series of 50 radical prostatectomy cases].
abstract: OBJECTIVE
  To refine the pretreatment staging of localized prostate cancers.
  
  
  METHODS
  Prospective study on 50 total prostatectomy specimens from men with apparently prostate-confined adenocarcinoma. Preoperative assay of the free PSA/total PSA ratio and analysis of this ratio according to the presence of capsular effraction, capsular invasion and positive margins.
  
  
  RESULTS
  Significant difference of this ratio according to the presence or absence of capsular effraction (13.2% versus 18.9%), capsular invasion (12.4% versus 17.5%) and positive margins (11.6% versus 16.3%).
  
  
  CONCLUSIONS
  The free PSA/total PSA ratio can be useful for staging of prostate cancer, but this needs to be confirmed by a large-scale prospective study.
authors.affiliation: Service d'Urologie, Hôpital Salvator, Marseille.
authors.forename: E
authors.initials: E
authors.lastname: Anfossi
authors.forename: D
authors.initials: D
authors.lastname: Rossi
authors.forename: V
authors.initials: V
authors.lastname: Grisoni
authors.forename: R
authors.initials: R
authors.lastname: Sauvan
authors.forename: F
authors.initials: F
authors.lastname: Bladou
authors.forename: G
authors.initials: G
authors.lastname: Serment
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000704:Analysis of Variance; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D011446:Prospective Studies; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery
chemical_list: D017430:Prostate-Specific Antigen
vernacular_title: Le rapport PSA libre/PSA total a-t-il sa place dans la stadification du cancer localisé de la prostate? A propos d'une série de 50 prostatectomies radicales.