Occupational allergic rhinitis and contact urticaria caused by bishop's weed (Ammi majus).
Bishop's weed (Ammi majus) has been known to induce toxic phytophotodermatitis. We now describe IgE-mediated rhinitis and contact urticaria caused by exposure to bishop's weed in a 31-year-old atopic female florist. A skin prick-prick test with bishop's weed flowers gave an 8-mm wheal, and the bishop's weed-specific IgE level in the patient's serum was 9.7 PRU/ml (RAST class 3). In an immunoblotting experiment with the patient's serum, nine IgE-binding protein bands with the molecular weights 19, 34, 39-41 (doublet), 52-61 (doublet), and >67 (triplet) kDa were detected in bishop's weed extract. The patient became symptomless after she had ceased to work as a florist.
Kiistala
R
R
Department of Allergic Diseases, Helsinki University Central Hospital, Finland.
Mäkinen-Kiljunen
S
S
Heikkinen
K
K
Rinne
J
J
Haahtela
T
T
D000328:Adult; D000485:Allergens / Q000276:immunology / Q000302:isolation & purification; D019661:Apiaceae / Q000009:adverse effects* / Q000737:chemistry / Q000276:immunology; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate; D007073:Immunoglobulin E / Q000276:immunology; D008970:Molecular Weight; D009299:Nasal Provocation Tests; D009784:Occupational Diseases / Q000209:etiology*; D010940:Plant Proteins / Q000276:immunology; D011058:Pollen / Q000276:immunology; D012129:Respiratory Function Tests; D012220:Rhinitis / Q000209:etiology* / Q000276:immunology; D012882:Skin Tests; D014581:Urticaria / Q000209:etiology* / Q000276:immunology
D000485:Allergens; D010940:Plant Proteins; D007073:Immunoglobulin E