title: Enzymatic formation of 2,3-diaminopropionic acid, the direct precursor of the neurotoxin beta-ODAP, in Lathyrus sativus.
abstract: The enzymatic breakdown of beta-(isoxazolin-5-on-2-yl)-L-alanine (BIA) with formation of 2,3-diaminopropionic acid (DAPA), the direct precursor of the neurotoxin beta-ODAP in Lathyrus sativus, was confirmed in vitro. Some properties of the enzyme responsible for the biosynthesis of DAPA are described.
authors.affiliation: Faculty of Pharmaceutical Sciences, Chiba University, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Ikegami
authors.forename: A
authors.initials: A
authors.lastname: Yamamoto
authors.forename: Y H
authors.initials: YH
authors.lastname: Kuo
authors.forename: F
authors.initials: F
authors.lastname: Lambein
mesh_terms: D000599:Amino Acids, Diamino / Q000378:metabolism*; D007887:Fabaceae / Q000737:chemistry / Q000378:metabolism*; D009498:Neurotoxins / Q000378:metabolism*; D010946:Plants, Medicinal; D015091:beta-Alanine / Q000031:analogs & derivatives* / Q000378:metabolism
chemical_list: D000599:Amino Acids, Diamino; D009498:Neurotoxins; D015091:beta-Alanine; C100126:oxalyldiaminopropionic acid; C011757:2,3-diaminopropionic acid