title: [Ischemic colitic in the elderly: predictive factors of gangrenous outcome].
abstract: OBJECTIVE
  To better characterize the presentation of gangrenous and non-gangrenous ischemic colitis in subjects older than 60 years, and to identify risk factors of gangrenous outcome.
  
  
  METHODS
  Retrospective analysis of 80 cases of ischemic colitis (22 male, 58 female; mean age 76.9 +/- 8.7 years) with 64 and 16 non gangrenous and gangrenous forms, respectively.
  
  
  RESULTS
  Hematochezia and diarrhea were significantly less prevalent in gangrenous colitis compared to the non-gangrenous group (31.2% vs 81.2%, P < 0.0001 and 6.2% vs 53.1%, P < 0.0001, respectively), whereas nausea and vomiting, and hyperleukcocytosis were significantly more frequent in the former group (50.0% vs 18.7%, P < 0.01 and 93.7% vs 62.5%, P < 0.02 respectively). Hypertension (P < 0.03), angina (P < 0.05), history of cancer (P < 0.03) and age older than 90 (P < 0.002) were risk factors for gangrenous outcome. After multivariate analysis, only two independent factors were identified, i.e.: hypertension and history of cancer. These factors predicted gangrenous course in 85% of cases.
  
  
  CONCLUSIONS
  Patients older than 60 years suffering from ischemic colitis are at high risk of gangrenous course if they have hypertension or history of cancer.
authors.affiliation: Service d'Hépato-Gastroentérologie, Hôtel-Dieu, CHU, Nantes.
authors.forename: J
authors.initials: J
authors.lastname: Barouk
authors.forename: J
authors.initials: J
authors.lastname: Gournay
authors.forename: P
authors.initials: P
authors.lastname: Bernard
authors.forename: C
authors.initials: C
authors.lastname: Masliah
authors.forename: J C
authors.initials: JC
authors.lastname: Le Neel
authors.forename: J P
authors.initials: JP
authors.lastname: Galmiche
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017091:Colitis, Ischemic / Q000150:complications / Q000473:pathology*; D018450:Disease Progression; D005260:Female; D005734:Gangrene / Q000209:etiology / Q000473:pathology*; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome
vernacular_title: Colite ischémique du sujet âgé: facteurs prédictifs de l'évolution gangreneuse.