The role of cyclooxygenase inhibition in the antineoplastic effects of nonsteroidal antiinflammatory drugs (NSAIDs).
Shiff
S J
SJ
Rockefeller University, New York, New York 10021-6399, USA. shiffs@rockvax.rockefeller.edu
Rigas
B
B
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D016718:Arachidonic Acid / Q000378:metabolism; D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000187:drug effects; D002273:Carcinogens / Q000378:metabolism; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D003110:Colonic Neoplasms / Q000517:prevention & control*; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology*; D004260:DNA Repair / Q000187:drug effects; D006801:Humans; D051379:Mice; D008954:Models, Biological; D016328:NF-kappa B / Q000187:drug effects
D000894:Anti-Inflammatory Agents, Non-Steroidal; D002273:Carcinogens; D016861:Cyclooxygenase Inhibitors; D016328:NF-kappa B; D016718:Arachidonic Acid; D017871:Calcium-Calmodulin-Dependent Protein Kinases