title: Synthesis of analogues of 5'-mono-, 5'-di-, and 5'-triphosphate-AZT for the development of specific enzyme immunoassay for monitoring of intracellular levels of AZT-MP, AZT-DP, and AZT-TP.
abstract: The synthesis of analogue compounds of polyphosphorylated AZT is described. The compounds are designed to raise specific antibodies against AZT-MP, -DP and -TP in rabbits.
authors.affiliation: Laboratoire de Synthèse Bioorganique associé au CNRS, Université Louis Pasteur, Faculté de pharmacie, Illkirch, France.
authors.forename: T
authors.initials: T
authors.lastname: Brossette
authors.forename: M C
authors.initials: MC
authors.lastname: Nevers
authors.forename: C
authors.initials: C
authors.lastname: Creminon
authors.forename: C
authors.initials: C
authors.lastname: Mioskowski
authors.forename: J
authors.initials: J
authors.lastname: Grassi
authors.forename: L
authors.initials: L
authors.lastname: Lebeau
mesh_terms: D000818:Animals; D019380:Anti-HIV Agents / Q000138:chemical synthesis / Q000378:metabolism; D007124:Immunoenzyme Techniques / Q000379:methods; D010766:Phosphorylation; D011817:Rabbits; D015215:Zidovudine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism
chemical_list: D019380:Anti-HIV Agents; D015215:Zidovudine