title: Cerebroretinal vasculopathy mimicking a brain tumor: a case of a rare hereditary syndrome.
abstract: We report a 35-year-old man with hereditary cerebroretinal vasculopathy (CRV) characterized by retinal microvascular changes and a right frontal intracerebral mass lesion that suggested a brain tumor. Histopathologic analysis of the patient's brain lesion as well as reviewed specimens of the patient's mother, who had reportedly died of a brain tumor, showed no neoplasia but did show cerebral microvasculopathy. CRV should be considered as a differential diagnosis for patients with intracerebral mass lesions, retinal vascular changes, and a positive family history of "brain tumors."
authors.affiliation: Department of Neurology, Ludwig-Maximilians-University, Munich, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Weil
authors.forename: G
authors.initials: G
authors.lastname: Reifenberger
authors.forename: C
authors.initials: C
authors.lastname: Dudel
authors.forename: T A
authors.initials: TA
authors.lastname: Yousry
authors.forename: S
authors.initials: S
authors.lastname: Schriever
authors.forename: S
authors.initials: S
authors.lastname: Noachtar
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012164:Retinal Diseases / Q000235:genetics* / Q000473:pathology*; D012171:Retinal Vessels / Q000473:pathology*; D013577:Syndrome