title: Synthetic hydroxyapatite orbital implants: a clinical and MRI evaluation.
abstract: OBJECTIVE
  Coralline hydroxypatite orbital implants have been used since the 1980s. More recently, synthetic hydroxyapatite orbital implants have been used, in both primary and secondary orbital implantation surgery. The implant may be drilled and pegged, if required, after adequate vascularisation of the implant has occurred. In this study we evaluated the clinical results and vascularisation of synthetic hydroxyapatite orbital implants.
  
  
  METHODS
  Twelve consecutive patients who had synthetic hydroxyapaptite orbital implants were evaluated clinically and 8 of these patients had orbital magnetic resonance imaging (MRI) scans with intravenous gadolinium performed at least 9 months post-operatively to assess vascularisation of the implant. Six patients had primary orbital implants at the time of enucleation and 6 patients had secondary implants.
  
  
  RESULTS
  No significant complications occurred following insertion of the synthetic hydroxyapatite orbital implants. All patients reported cosmetic satisfaction with the results of surgery. MRI scans revealed inhomogeneous enhancement in 3 of the 4 patients receiving primary implants. All patients with secondary implants and 1 patients who had a primary implant had moderate to large areas of poor enhancement in the implant.
  
  
  CONCLUSIONS
  Synthetic hydroxyapatite implants gave good clinical results but variable vascularisation occurs, especially with secondary implants.
authors.affiliation: Department of Ophthalmology, Leicester Royal Infirmary, UK.
authors.forename: N
authors.initials: N
authors.lastname: Sarvananthan
authors.forename: A J
authors.initials: AJ
authors.lastname: Liddicoat
authors.forename: G T
authors.initials: GT
authors.lastname: Fahy
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001672:Biocompatible Materials; D017886:Durapatite; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018919:Neovascularization, Physiologic; D009915:Orbit / Q000098:blood supply; D020273:Orbital Implants; D011184:Postoperative Period
chemical_list: D001672:Biocompatible Materials; D017886:Durapatite