Enzymatic formation of 2,3-diaminopropionic acid, the direct precursor of the neurotoxin beta-ODAP, in Lathyrus sativus.
The enzymatic breakdown of beta-(isoxazolin-5-on-2-yl)-L-alanine (BIA) with formation of 2,3-diaminopropionic acid (DAPA), the direct precursor of the neurotoxin beta-ODAP in Lathyrus sativus, was confirmed in vitro. Some properties of the enzyme responsible for the biosynthesis of DAPA are described.
Ikegami
F
F
Faculty of Pharmaceutical Sciences, Chiba University, Japan.
Yamamoto
A
A
Kuo
Y H
YH
Lambein
F
F
D000599:Amino Acids, Diamino / Q000378:metabolism*; D007887:Fabaceae / Q000737:chemistry / Q000378:metabolism*; D009498:Neurotoxins / Q000378:metabolism*; D010946:Plants, Medicinal; D015091:beta-Alanine / Q000031:analogs & derivatives* / Q000378:metabolism
D000599:Amino Acids, Diamino; D009498:Neurotoxins; D015091:beta-Alanine; C100126:oxalyldiaminopropionic acid; C011757:2,3-diaminopropionic acid