title: [Rothmund-Thomson syndrome and osteosarcoma].
abstract: Until now less than 200 cases of Rothmund Thomson syndrome (RTS) also called Poikiloderma atrophicans have been reported. RTS is an autosomal recessive dermatosis characterized by athropy and teleangiectasia of the skin, juvenile cataract, hypogonadism and sceletal abnormalities. These osseous disorders include cortical hyperostosis mimicking rickets or chondrodysthropy and may mask early signs of malignant disorders. This seems to be a problem due to the fact that there is an association between osteosarcoma and RTS. The radiologic findings of both RTS and osteosarcoma in a 7 year old female are discussed.
authors.affiliation: Klinik für Radiologische Diagnostik und Nuklearmedizin, Katholisches Marienhospital Herne, Universitätsklinik der Ruhr-Universität Bochum.
authors.forename: J
authors.initials: J
authors.lastname: Kirchner
authors.forename: H
authors.initials: H
authors.lastname: Schmidt
authors.forename: A
authors.initials: A
authors.lastname: Hörlin
authors.forename: E M
authors.initials: EM
authors.lastname: Schilling
mesh_terms: D001846:Bone Development; D002648:Child; D002675:Child, Preschool; D005260:Female; D005528:Foot / Q000000981:diagnostic imaging; D006130:Growth Disorders; D006225:Hand / Q000000981:diagnostic imaging; D006801:Humans; D012516:Osteosarcoma / Q000150:complications* / Q000000981:diagnostic imaging; D011859:Radiography; D011038:Rothmund-Thomson Syndrome / Q000150:complications* / Q000000981:diagnostic imaging
vernacular_title: Rothmund-Thomson-Syndrom und Osteosarkom.