[Association between human papillomavirus infection, premalignant lesions of anal cancer, and the human immunodeficiency virus: prospective study on subjects with condylomata acuminata].
BACKGROUND
Human immunodeficiency virus (HIV) increases the risk for anal premalignant lesions associated to human papillomavirus infection (HPV). The aim of this study was to compare the prevalence of HPV and squamous intraepithelial lesions (SIL) in patients with anal warts, with and without anti-HIV antibodies.


METHODS
HPV was identified using in situ hybridization and SIL was classified in high and low grade.


RESULTS
HPV infection was more frequent in anti-HIV positive patients although the difference was not statistically significant. All patients with a high grade SIL were anti-HIV positive (p < 0.05).


CONCLUSIONS
HIV infection was associated with a high rate of high-grade SIL.
Pera
M
M
Servicio de Cirugía General y Digestiva, Hospital Clínic i Provincial, Universidad de Barcelona.
Sugrañes
G
G
Ordi
J
J
Trias
M
M
D000328:Adult; D001004:Anus Diseases / Q000453:epidemiology* / Q000821:virology*; D001005:Anus Neoplasms / Q000453:epidemiology* / Q000821:virology*; D003218:Condylomata Acuminata / Q000453:epidemiology* / Q000821:virology*; D005260:Female; D015658:HIV Infections / Q000821:virology*; D006801:Humans; D008297:Male; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology*; D011230:Precancerous Conditions / Q000453:epidemiology* / Q000821:virology*; D015995:Prevalence; D011446:Prospective Studies; D014412:Tumor Virus Infections / Q000453:epidemiology* / Q000821:virology*
Asociación entre la infección por el virus del papiloma humano, las lesiones premalignas del cáncer anal y el virus de la inmunodeficiencia humana: estudio prospectivo en individuos con condilomas acuminados.