title: Partitioning the mortality risk associated with inadequate passive transfer of colostral immunoglobulins in dairy calves.
abstract: This study developed a method to partition the risk of mortality in dairy calves in the 1st 16 weeks of life. Observed population mortality and the relative risk of mortality in each serum protein concentration stratum were used to determine the population baseline mortality rate and the mortality rate due to inadequate passive transfer of colostral immunoglobulin. A total of 3,479 calves were studied, 8.2% of which died before 16 weeks of age. The population baseline mortality rate was 5.0% and the mortality rate due to inadequate passive transfer was 3.2%. Thirty-nine percent of the observed mortality was attributed to inadequate passive transfer. This partitioning of risk between passive transfer-related and unrelated sources should prove useful in conducting investigations of calf mortality problems in dairy herds.
authors.affiliation: Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA. tyler@missouri.edu
authors.forename: J W
authors.initials: JW
authors.lastname: Tyler
authors.forename: D D
authors.initials: DD
authors.lastname: Hancock
authors.forename: J G
authors.initials: JG
authors.lastname: Thorne
authors.forename: C C
authors.initials: CC
authors.lastname: Gay
authors.forename: J M
authors.initials: JM
authors.lastname: Gay
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology* / Q000401:mortality; D005260:Female; D007116:Immunization, Passive / Q000662:veterinary*; D007071:Immunoglobulin A, Secretory; D008297:Male; D015233:Models, Statistical; D018570:Risk Assessment
chemical_list: D007071:Immunoglobulin A, Secretory