Cytochrome P450-dependent metabolism of arachidonic acid.
The cytochrome P450-dependent metabolism of arachidonic acid, the mechanisms of regulation of stereo- and regiospecificity by cytochrome P450 isoenzymes, and the biological relevance of metabolites of the arachidonic acid cascade is discussed in this review.
Ivanov
I V
IV
Lomonosov State Academy of Fine Chemical Technology, Moscow, 117571, Russia.
Groza
N V
NV
Myagkova
G I
GI
D000818:Animals; D016718:Arachidonic Acid / Q000378:metabolism*; D001711:Biotransformation; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D010084:Oxidation-Reduction
D007527:Isoenzymes; D016718:Arachidonic Acid; D003577:Cytochrome P-450 Enzyme System