Differential expression of the Drosophila zinc finger gene jim in the follicular epithelium.
The Drosophila gene jim was identified by an enhancer trap line showing asymmetric dorso-ventral expression in the follicular epithelium. It gives rise to the jim-1 and jim-2 transcripts that contain distinct 5'-UTRs but encode the same nine C(2)H(2) zinc finger protein. From stage 10A onward, jim-1 RNA is transcribed in squamous cells while jim-2 RNA is specific to all non-antero-dorsal columnar cells as the result of repression in antero-dorsal cells by the DER pathway.
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Institut Jacques Monod, Equipe de Biologie du Développement, UMR 7592, CNRS and Universités Denis-Diderot Paris 7 and Paris 6 Pierre et Marie Curie, 2 place Jussieu, F-75251, Paris Cedex 05, France.
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Yanicostas
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D000595:Amino Acid Sequence; D000818:Animals; D002352:Carrier Proteins / Q000235:genetics* / Q000378:metabolism; D003001:Cloning, Molecular; D004330:Drosophila / Q000235:genetics*; D029721:Drosophila Proteins; D004847:Epithelial Cells / Q000166:cytology / Q000502:physiology; D005260:Female; D018507:Gene Expression Regulation, Developmental; D006720:Homozygote; D019476:Insect Proteins / Q000235:genetics; D008969:Molecular Sequence Data; D009154:Mutation; D006080:Ovarian Follicle / Q000166:cytology / Q000254:growth & development*; D010053:Ovary / Q000502:physiology; D011817:Rabbits; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors; D016211:Transforming Growth Factor alpha; D015291:Transforming Growth Factors / Q000235:genetics; D016335:Zinc Fingers / Q000235:genetics*
D002352:Carrier Proteins; D029721:Drosophila Proteins; D019476:Insect Proteins; C121966:Jim protein, Drosophila; D014157:Transcription Factors; D016211:Transforming Growth Factor alpha; C083730:grk protein, Drosophila; D015291:Transforming Growth Factors