title: Haemodynamic changes after tracheal intubation in cigarette smokers compared with non-smokers.
abstract: We have studied the haemodynamic changes in response to tracheal intubation in 60 ASA I women undergoing elective gynaecological surgery; 30 women smoked more than 10 cigarettes a day, while the other 30 were non-smokers. Immediately after intubation, heart rate of smokers (mean 102.0 (SD 17) beat min-1) was significantly greater (P < 0.01) than that of non-smokers (mean 91.0 (12.3) beat min-1). This may be clinically important in smokers who are at risk of ischaemic heart disease and also relevant for future studies investigating haemodynamic responses to intubation.
authors.affiliation: Royal Devon and Exeter Hospital, Wonford, UK.
authors.forename: C H
authors.initials: CH
authors.lastname: Laxton
authors.forename: Q
authors.initials: Q
authors.lastname: Milner
authors.forename: P J
authors.initials: PJ
authors.lastname: Murphy
mesh_terms: D000328:Adult; D005260:Female; D013509:Gynecologic Surgical Procedures; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D007442:Intubation, Intratracheal; D008875:Middle Aged; D012907:Smoking / Q000503:physiopathology*