title: Optimality score for the neurologic examination of the infant at 12 and 18 months of age.
abstract: The aim of this study was to develop and validate a simple, quantifiable, neurologic examination for infants between 2 and 24 months of age. The assessment consists of 37 items, divided into 3 sections. The first section includes 26 items assessing cranial nerve function, posture, movements, tone, and reflexes; the second section of 8 items documents the development of motor function, and the third section of 3 items evaluates the state of behavior. We applied this assessment to a cohort of ninety-two 12-month-old infants and forty-three 18-month-old infants, with no known perinatal risk factors. The proforma presented has been designed according to the frequency distribution of the neurologic findings in this cohort. Each item is scored individually, and a global score is the sum of all individual scores. The quantitative score enhances the value of this examination, both in clinical practice and in research settings.
authors.affiliation: Department of Pediatrics, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom.
authors.forename: L
authors.initials: L
authors.lastname: Haataja
authors.forename: E
authors.initials: E
authors.lastname: Mercuri
authors.forename: R
authors.initials: R
authors.lastname: Regev
authors.forename: F
authors.initials: F
authors.lastname: Cowan
authors.forename: M
authors.initials: M
authors.lastname: Rutherford
authors.forename: V
authors.initials: V
authors.lastname: Dubowitz
authors.forename: L
authors.initials: L
authors.lastname: Dubowitz
mesh_terms: D001519:Behavior / Q000502:physiology; D002657:Child Development / Q000502:physiology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009048:Motor Skills / Q000502:physiology; D009460:Neurologic Examination / Q000379:methods*; D012016:Reference Values; D015203:Reproducibility of Results