title: Antibacterial activity of some indigenous plants used for the treatment of wounds in the Eastern Cape, South Africa.
abstract: The use of medicinal plants in the world, and especially in South Africa, contributes significantly to primary health care. This paper presents the findings of an initial survey of plants used for the treatment of wounds in the Eastern Cape Province, South Africa. Ethnomedical information gathered from surveys at clinics, hospitals as well as interviews with traditional healers and rural dwellers has revealed that Grewia occidentalis, Polystichum pungens, Cheilanthes viridis and Malva parvifolia are the most commonly used plants for the treatment of wounds in the province. The methanol extracts of G. occidentalis, P. pungens and C. viridis showed significant inhibition against gram-positive and gram-negative bacteria, while the acetone extract of P. pungens inhibited the gram-positive bacteria only. Extracts from M. parvifolia did not show any antibacterial activity at 5.0 mg/ml. Generally, the antibacterial property of the plants appears to have justified their use for the treatment of wounds, which are contaminated through bacterial infection, in the province.
authors.affiliation: Botany Department, University of Fort Hare, Alice, South Africa.
authors.forename: D S
authors.initials: DS
authors.lastname: Grierson
authors.forename: A J
authors.initials: AJ
authors.lastname: Afolayan
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D016488:Medicine, African Traditional; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D010946:Plants, Medicinal / Q000737:chemistry*; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts