Synthesis of new PMEA diphosphate mimics.
We synthesized and characterized new diphosphate mimics of the acyclic nucleoside phosphonate PMEA [Adefovir, 9-(2-phosphonylmethoxyethyl)adenine].
Laux
W H
WH
Laboratoire de Chimie Bioorganique, UMR CNRS-USTL 5625, Université Montpellier II, France.
Périgaud
C
C
Imbach
J L
JL
Gosselin
G
G
D000225:Adenine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry; D002852:Chromatography, Ion Exchange; D063065:Organophosphonates; D009943:Organophosphorus Compounds / Q000138:chemical synthesis
D000998:Antiviral Agents; D063065:Organophosphonates; D009943:Organophosphorus Compounds; C053001:adefovir; D000225:Adenine