Vibrational study of a nucleoside analogue with antiviral activity, 5-chloro-2'-deoxyuridine, CDU.
The experimental FTIR and FT-Raman spectra of 5-chloro-2'-deoxyuridine have been assigned on the basis of normal coordinate analyses, in the light of observed and calculated wavenumbers and isotopic shifts. The results indicate that virtually all normal modes of IDU involve some degree of vibrational coupling between the chlorouracil base and the deoxyribose moiety.
Bailey
L
L
Departamento de Ciencias y Técnicas Fisicoquímicas, UNED, Madrid, Spain.
Navarro
R
R
Hernanz
A
A
D000998:Antiviral Agents / Q000737:chemistry*; D003857:Deoxyuridine / Q000031:analogs & derivatives* / Q000737:chemistry; D009690:Nucleic Acid Conformation; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman
D000998:Antiviral Agents; C012244:5-chloro-2'-deoxyuridine; D003857:Deoxyuridine