title: [Evaluation of the individual absolute cardiovascular risk. A mathematical equation and/or arterial measurement?].
abstract: The latest recommendations about the management of cardiovascular risk factors take into account not only the level of risk factor but also the global risk profile of the patient. The reference for the calculated estimation of absolute cardiovascular risk remains the Framingham equation. Nevertheless, this estimation has a number of operational and conceptual limitations such as geographical and historical validity and its application to individual cases. Different results in the medical literature suggest that parameters of arterial structure or function measured simply, such as arterial rigidity, could be closely related to the level of individual cardiovascular risk by the integration of the deleterious effects of different vascular risk factors over decades of exposition. They could then be better predict cardiovascular effects than the result of a mathematical equation which only integrates some of the risk factors at a given point in time. These simple, rapid and non-invasive measurements could help identify subjects at high cardiovascular risk and also help the clinician in the orientation of preventive measures in subjects with cardiovascular risk factors.
authors.affiliation: Service de médecine interne-thérapeutique, INSERM U 337, hôpital Broussais, Paris.
authors.forename: J
authors.initials: J
authors.lastname: Blacher
authors.forename: L
authors.initials: L
authors.lastname: Bortolotto
authors.forename: P
authors.initials: P
authors.lastname: Iaria
authors.forename: G
authors.initials: G
authors.lastname: London
authors.forename: M
authors.initials: M
authors.lastname: Safar
mesh_terms: D000328:Adult; D000368:Aged; D001158:Arteries / Q000473:pathology* / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000401:mortality / Q000517:prevention & control*; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D012372:ROC Curve; D018570:Risk Assessment; D015996:Survival Rate; D013997:Time Factors
vernacular_title: Evaluation du risque cardiovasculaire absolu individuel. Equation mathématique et (ou) mesure artérielle?