Cathepsin B inhibitors do not prevent the intracellular trypsinogen activation by secretagogue hyperstimulation.
Otani
T
T
Department of Hepatobiliary and Pancreatic Surgery, University of Tokyo, Japan.
Matsukura
A
A
D000208:Acute Disease; D002401:Cathepsin B / Q000037:antagonists & inhibitors / Q000378:metabolism*; D015853:Cysteine Proteinase Inhibitors / Q000494:pharmacology; D004151:Dipeptides / Q000494:pharmacology; D004789:Enzyme Activation; D006801:Humans; D007930:Leucine / Q000031:analogs & derivatives / Q000494:pharmacology; D010195:Pancreatitis / Q000201:enzymology*; D010879:Piperazines / Q000494:pharmacology; D011480:Protease Inhibitors / Q000494:pharmacology*; D014362:Trypsinogen / Q000378:metabolism*
D015853:Cysteine Proteinase Inhibitors; D004151:Dipeptides; D010879:Piperazines; D011480:Protease Inhibitors; C068250:N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline; C036798:NCO 700; D014362:Trypsinogen; D002401:Cathepsin B; D007930:Leucine; C024974:E 64