title: Determination of some insect repellents in cosmetic products by high-performance thin-layer chromatography.
abstract: A simple and reliable thin-layer chromatographic method for the determination of N,N-diethyl-m-toluamide (DEET) and dimethyl phthalate (DMP) in raw material and cosmetic products was developed and validated. A benzene-diethyl ether-cyclohexane (5:3:2, v/v/v) solvent system was used for quantitative evaluation of chromatograms. The chromatographic zones corresponding to the spots of DEET and DMP on the silica gel plates were scanned in the reflectance/absorbance mode at 230 nm. The method was found to be reproducible and convenient for the quantitative analysis of DEET and DMF in raw material and cosmetic products.
authors.affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Belgrade, Serbia, Yugoslavia.
authors.forename: G
authors.initials: G
authors.lastname: Markovic
authors.forename: D
authors.initials: D
authors.lastname: Agbaba
authors.forename: D Z
authors.initials: DZ
authors.lastname: Stakic
authors.forename: S
authors.initials: S
authors.lastname: Vladimirov
mesh_terms: D002855:Chromatography, Thin Layer / Q000379:methods*; D003358:Cosmetics / Q000737:chemistry*; D003671:DEET / Q000032:analysis*; D007302:Insect Repellents / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D003358:Cosmetics; D007302:Insect Repellents; D003671:DEET