[Defense mechanisms in the peritoneum].
There are many specialised defence mechanisms connected with immunity of peritoneal cavity. These are absorbtion of bacteria and their toxins from peritoneum, phagocytosis, opsonization, activation of the complement and separation of infection in the peritoneal cavity. A very important role in defence mechanisms of peritoneal cavity play GALT and PALT. Among many cells of the immune system mastocytes and gamma delta T cells have important role in induction and regulation of immune mechanisms in the peritoneal cavity. Lymphocytes T gamma delta release many cytokines and chemokines what allows them to play their protecting role during peritonitis. Released cytokines (especially IFN-gamma) activate macrophages to produce and secret many proinflammatory cytokines and factors. On the other hand mast cells play their role in defence of peritoneal cavity via TNF-alpha and histamine release and inhibition of fibrynolysis.
Szczepanik
M
M
Katedry Immunologii, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
Gryglewski
A
A
Solecki
R
R
D000818:Animals; D003167:Complement Activation / Q000276:immunology; D016207:Cytokines / Q000378:metabolism; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D008407:Mast Cells / Q000276:immunology; D010537:Peritoneum / Q000276:immunology*; D010538:Peritonitis / Q000276:immunology; D010587:Phagocytosis / Q000276:immunology
D016207:Cytokines
Mechanizmy odpornościowe otrzewnej.