title: MRI findings of benign monomelic amyotrophy of lower limb.
abstract: We report here magnetic resonance imaging (MRI) findings of two patients with benign monomelic amyotrophy of lower limb. Both subjects showed unilateral amyotrophy of the lower limb with a benign clinical course, and the affected muscles demonstrated neurogenic changes. On T1- and T2-weighted MRI, marked atrophy and increased signal intensity were found mainly in gastrocnemius and soleus muscles. Moreover, MRI examination also revealed that thigh muscles including semitendinosus, semimembranosus, and vastus intermedius and lateralis muscles were involved in one of the patients. We concluded that muscle MRI is very useful for detecting affected muscles, especially deep skeletal muscles in patients with benign monomelic amyotrophy of lower limb.
authors.affiliation: Second Department of Internal Medicine, Fukui Medical University, Yoshida-gun, Japan. hamano@fmsrsa.fukui-med.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Hamano
authors.forename: T
authors.initials: T
authors.lastname: Mutoh
authors.forename: M
authors.initials: M
authors.lastname: Hirayama
authors.forename: K
authors.initials: K
authors.lastname: Ito
authors.forename: M
authors.initials: M
authors.lastname: Kimura
authors.forename: T
authors.initials: T
authors.lastname: Aita
authors.forename: K
authors.initials: K
authors.lastname: Kiyosawa
authors.forename: T
authors.initials: T
authors.lastname: Ohtaki
authors.forename: M
authors.initials: M
authors.lastname: Kuriyama
mesh_terms: D000328:Adult; D004576:Electromyography; D006801:Humans; D007866:Leg / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D009133:Muscular Atrophy / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D009431:Neural Conduction