A new anti-HBeAg lignan, kadsumarin A, from Kadsura matsudai and Schizandra arisanensis.
A new C18 dibenzocyclooctadiene lignan, kadsumarin A (1) was isolated from Kadsura matsudai Hayata and Schizandra arisanensis Hayata. The anti-HBeAg test revealed that kadsumarin A had activity at a concentration of 40 micrograms/ml (= 90.1 microM). Its structural elucidation by spectral analysis was discussed in this note.
Kuo
Y H
YH
National Research Institute of Chinese Medicine, Taipei, Taiwan, Republic of China.
Li
S Y
SY
Wu
M D
MD
Huang
R L
RL
Yang Kuo
L M
LM
Chen
C F
CF
D005663:Furans / Q000737:chemistry / Q000302:isolation & purification*; D006510:Hepatitis B Antibodies / Q000737:chemistry*; D017705:Lignans; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013141:Spiro Compounds / Q000737:chemistry / Q000302:isolation & purification*; D013624:Taiwan
D005663:Furans; D006510:Hepatitis B Antibodies; D017705:Lignans; D013141:Spiro Compounds; C122041:kadsumarin A