title: Systemic lupus erythematosus with a giant rectal ulcer and perforation.
abstract: A 41-year-old man with systemic lupus erythematosus (SLE) who developed pelvic inflammation due to perforation of a giant rectal ulcer is described. The patient presented with persistent diarrhea, abdominal pain and fever without development of disease activity of SLE. Endoscopic and radiological examinations revealed a perforated giant ulcer on the posterior wall at the rectum below the peritoneal evagination. The ulcerated area was decreased after a colostomy was performed at the transverse colon to preserve anal function. The patient is currently being monitored on an outpatient basis. It should be noted that life-threatening complications such as perforated ulcer of the intestinal tract could occur without SLE disease activity.
authors.affiliation: Fourth Department of Internal Medicine, Sapporo Medical University, School of Medicine.
authors.forename: J
authors.initials: J
authors.lastname: Teramoto
authors.forename: Y
authors.initials: Y
authors.lastname: Takahashi
authors.forename: S
authors.initials: S
authors.lastname: Katsuki
authors.forename: T
authors.initials: T
authors.lastname: Sato
authors.forename: S
authors.initials: S
authors.lastname: Sakamaki
authors.forename: D
authors.initials: D
authors.lastname: Kobayashi
authors.forename: N
authors.initials: N
authors.lastname: Watanabe
authors.forename: Y
authors.initials: Y
authors.lastname: Niitsu
mesh_terms: D000328:Adult; D003125:Colostomy; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D008297:Male; D012002:Rectal Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014456:Ulcer / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy