title: Acute hand ischemia secondary to intraarterial buprenorphine injection: treatment with iloprost and dextran-40--a case report.
abstract: Intraarterial injection may result in acute ischemia and amputation. The authors describe the case of a 27-year-old man with an acute hand ischemia following intraarterial injection of a suspension of buprenorphine. Despite its initial severity, this case was successfully treated with iloprost, a stable prostacyclin analogue, and dextran-40, a low-molecular-weight dextran.
authors.affiliation: Department of Vascular Surgery, Tenon Hospital, Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Gouny
authors.forename: J P
authors.initials: JP
authors.lastname: Gaitz
authors.forename: M
authors.initials: M
authors.lastname: Vayssairat
mesh_terms: D000208:Acute Disease; D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use*; D002047:Buprenorphine / Q000008:administration & dosage / Q000009:adverse effects*; D003911:Dextrans / Q000008:administration & dosage / Q000627:therapeutic use*; D006225:Hand / Q000098:blood supply*; D006801:Humans; D016285:Iloprost / Q000008:administration & dosage / Q000627:therapeutic use*; D007262:Infusions, Intravenous; D007269:Injections, Intra-Arterial / Q000009:adverse effects; D007275:Injections, Intravenous; D007511:Ischemia / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D009294:Narcotics / Q000008:administration & dosage / Q000009:adverse effects*; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000925:Anticoagulants; D003911:Dextrans; D009294:Narcotics; D014665:Vasodilator Agents; D002047:Buprenorphine; D016285:Iloprost