Themes from a NASA workshop on gene regulatory processes in development and evolution.
A memorable workshop, focused on causal mechanisms in metazoan evolution and sponsored by NASA, was held in early June 1998, at MBL. The workshop was organized by Mike Levine and Eric H. Davidson, and it included the PI and associates from 12 different laboratories, a total of about 30 people. Each laboratory had about two and one half hours in which to represent its recent research and cast up its current ideas for an often intense discussion. In the following we have tried to enunciate some of the major themes that emerged, and to reflect on their implications. The opinions voiced are our own. We would like to tender apologies over those contributions we have not been able to include, but this is not, strictly speaking, a meeting review. Rather we have focused on those topics that bear more directly on evolutionary mechanisms, and have therefore slighted some presentations (including some of our own), that were oriented mainly toward developmental processes. J. Exp. Zool. (Mol. Dev. Evol. ) 285:104-115, 1999.
Davidson
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Division of Biology 156-29, California Institute of Technology, Pasadena, California 91125, USA. davidson@mirsky.caltech.edu
Ruvkun
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D000818:Animals; D005075:Biological Evolution; D019521:Body Patterning; D017173:Caenorhabditis elegans / Q000235:genetics; D019143:Evolution, Molecular; D005786:Gene Expression Regulation; D005801:Genes, Homeobox; D010802:Phylogeny; D014481:United States; D018557:United States National Aeronautics and Space Administration