[Homocysteine--a routine biochemical parameter in cardiovascular diseases?].
An elevated level of total homocysteine (tHcy) in blood-hyperhomocysteinemia, is prevalent and strong risk factor for atherosclerotic vascular disease in the coronary, cerebral and peripheral vessels and for thromboembolism (arterial and venous). Elevated total homocysteine confers a graded risk with no threshold, is independent of but may enhance the effect of conventional risk factors. Hyperhomocysteinemia seems to be a particularly strong predictor of cardiovaskular mortality. Supplementation with B-vitamins, in particular with folic acid, is an efficient, safe and inexpensive means to reduce an elevated total homocysteine level.
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Oddelenie klinickej biochémie NsP F. D. Roosevelta, Banská Bystrica.
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Hricová
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Zacharová
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D001161:Arteriosclerosis / Q000097:blood; D002318:Cardiovascular Diseases / Q000097:blood* / Q000401:mortality; D006710:Homocysteine / Q000097:blood* / Q000378:metabolism; D006801:Humans; D012307:Risk Factors
D006710:Homocysteine
Homocysteín--rutinný biochemický parameter pri kardiovaskulárnych ochoreniach?