[Acetaminophen hepatotoxicity in an alcohol addicted student. Case report].
We report a 12 years old male with a history of excessive alcohol intake, that developed a severe liver failure after the use of acetaminophen in therapeutic doses. He presented with encephalopathy, jaundice, fever and an upper gastrointestinal bleeding. Serum aspartate aminotransferase values were 5,250 IU/L. The patient received supportive care and oral corticosteroids, remained severely compromised for 72 hours and had a good evolution thereafter. The association of acetaminophen use and excessive alcohol intake in a patient who developed an acute hepatic failure and the absence of serological evidence of hepatitis A or B viral infection, support the diagnosis of drug induced liver failure.
Fercovic
A
A
Hospital de Quellón, Santiago, Chile.
Serra
I
I
Serra
L
L
D000082:Acetaminophen / Q000506:poisoning*; D000428:Alcohol Drinking / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D002648:Child; D006801:Humans; D008297:Male
D000082:Acetaminophen
Hepatotoxidad por acetaminofeno en un escolar con ingesta habitual de alcohol. Caso clínico.