Gastric carcinoma in Sotos syndrome (cerebral gigantism).
We report the first case of the association of Sotos syndrome and gastric carcinoma (containing signet ring cells) in a twin patient. The other-probably monozygous-twin is also affected by the Sotos syndrome. The association of malign tumors in Sotos syndrome and other overgrowth syndromes is discussed.
Le Marec
B
B
Service de Génétique Médicale, CHRU, Hôpital Pontchaillou, Rennes, France.
Pasquier
L
L
Dugast
C
C
Gosselin
M
M
Odent
S
S
D000328:Adult; D001927:Brain Diseases / Q000235:genetics*; D018279:Carcinoma, Signet Ring Cell / Q000235:genetics*; D005877:Gigantism / Q000235:genetics*; D006801:Humans; D013274:Stomach Neoplasms / Q000235:genetics*; D014430:Twins, Monozygotic