Influence of the acute intraperitoneal administration of tetrazepam on blood glucose level and serum lipids in normoglycemic and normolipidemic rats.
The acute i.p. administration of tetrazepam (5, 7.5, 15 mg/kg) in normoglycemic and normolipidemic rats induced an increase in blood glucose level, a delay of fibrinolysis (when administered at the first two doses) and variable changes of serum lipids. These results are different from those obtained in hyperlipidemic rats treated with tetrazepam.
Horák
J
J
Department of Pharmacology, University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Cuparencu
B
B
Horák
A
A
D000818:Animals; D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001569:Benzodiazepines; D001786:Blood Glucose / Q000187:drug effects / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood; D011345:Fenofibrate / Q000494:pharmacology; D005342:Fibrinolysis / Q000187:drug effects; D006949:Hyperlipidemias / Q000097:blood*; D007274:Injections, Intraperitoneal; D008055:Lipids / Q000097:blood*; D008297:Male; D009125:Muscle Relaxants, Central / Q000008:administration & dosage / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D012016:Reference Values; D014280:Triglycerides / Q000097:blood
D014151:Anti-Anxiety Agents; D001786:Blood Glucose; D008055:Lipids; D009125:Muscle Relaxants, Central; D014280:Triglycerides; D001569:Benzodiazepines; D002784:Cholesterol; C005245:tetrazepam; D011345:Fenofibrate