title: Long-term preservation of voice improvement following surgical medialization and reinnervation for unilateral vocal fold paralysis.
abstract: In June of 1996, we reported improved functional voice results when reinnervation was combined with surgical medialization for unilateral vocal fold paralysis. In addition, it was noted that further wasting of the reinnervated vocal fold was prevented in 96% of these patients beyond 2 years' follow-up. The study reported here compares the long-term preservation of voice improvement achieved by surgical medialization alone with that resulting from combined medialization and nerve-muscle pedicle reinnervation. Further significant wasting of the paralyzed vocal fold with voice deterioration from that achieved by surgical medialization alone was noted between 6 months and 2 years postoperatively in 28% of patients, while only 4% of those undergoing combined reinnervation demonstrated this finding at a minimum of 2 years' follow-up.
authors.affiliation: Department of Otolaryngology/Head and Neck Surgery, Case-Western Reserve University School of Medicine, Cleveland, Ohio 44106-5045, USA.
authors.forename: H M
authors.initials: HM
authors.lastname: Tucker
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007821:Laryngeal Muscles / Q000601:surgery; D007823:Laryngeal Nerves / Q000601:surgery; D008297:Male; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000601:surgery*; D014827:Vocal Cords / Q000294:innervation*; D014833:Voice Quality