Amyotrophic lateral sclerosis syndrome and hyperthyroidism: report of 4 patients.
Four patients with clinical diagnosis of amyotrophic lateral sclerosis syndrome and laboratory results of hyperthyroidism were reported. There were 3 women aged 27, 59, 59 years and 1 man aged 50 years. All of them had symptoms and signs of dysarthria and dysphagia, fasciculations of the tongue, muscle weakness with generalized hyperreflexia. After treatment with antithyroid drugs, motor weakness and dysphagia improved.
Chotmongkol
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Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand.
D000328:Adult; D000690:Amyotrophic Lateral Sclerosis / Q000150:complications* / Q000188:drug therapy; D013956:Antithyroid Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008713:Methimazole / Q000627:therapeutic use; D008875:Middle Aged; D016896:Treatment Outcome
D013956:Antithyroid Agents; D008713:Methimazole