title: Synthesis of some fully 3' and 4'-C-branched-chain sugar nucleoside analogues.
abstract: The synthesis of some new 3'-azido-3'-C-substituted pyrimidine nucleoside analogues is described. The key step is the geminal disubstitution of an appropriated ketone carbohydrate, via the regioselective ring opening of the corresponding tosyl-epoxide derivative.
authors.affiliation: CNRS-UM II 5625, Laboratoire de Chimie Bioorganique, Université Montpellier II, France.
authors.forename: T
authors.initials: T
authors.lastname: Ton-That
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D015497:HIV-1 / Q000187:drug effects / Q000502:physiology; D006515:Hepatitis B virus / Q000187:drug effects / Q000502:physiology; D008826:Microbial Sensitivity Tests; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D014779:Virus Replication / Q000187:drug effects
chemical_list: D002241:Carbohydrates; D009705:Nucleosides