title: Effects of an ionic and nonionic contrast agent on von Willebrand factor assessed during coronary angiography.
abstract: This study shows an increase in von Willebrand factor antigen in blood collected from the coronary sinus shortly after coronary angiography with an ionic contrast agent (diatrizoate), but not a nonionic contrast agent (iohexol). These findings suggest that ionic contrast agents may cause more endothelial injury than nonionic contrast agents.
authors.affiliation: Center for Thrombosis and Hemostasis, Department of Medicine (Cardiology Division), University of North Carolina, Chapel Hill, USA. dehmer.car1@mail.unch.unc.edu
authors.forename: G J
authors.initials: GJ
authors.lastname: Dehmer
authors.forename: T C
authors.initials: TC
authors.lastname: Nichols
authors.forename: S
authors.initials: S
authors.lastname: Li
authors.forename: G G
authors.initials: GG
authors.lastname: Koch
authors.forename: D A
authors.initials: DA
authors.lastname: Tate
authors.forename: T R
authors.initials: TR
authors.lastname: Griggs
mesh_terms: D003287:Contrast Media / Q000494:pharmacology*; D017023:Coronary Angiography / Q000379:methods*; D003327:Coronary Disease / Q000097:blood / Q000000981:diagnostic imaging*; D003973:Diatrizoate / Q000494:pharmacology; D005260:Female; D006801:Humans; D007472:Iohexol / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D014841:von Willebrand Factor / Q000032:analysis*
chemical_list: D003287:Contrast Media; D014841:von Willebrand Factor; D003973:Diatrizoate; D007472:Iohexol