title: [Serous detection of the neuroretina in Waldenström disease. A case report].
abstract: BACKGROUND
  Waldenstrom's Macroglobulinemia is a monoclonal gammopathy producing pathologic IgM antibodies with increased blood viscosity, platelet dysfunction and retinal hemorrhages. As a complication a serous detachment of the macula is described. The pathogenesis of the serous detachment is still not fully understood.
  
  
  METHODS
  A 73-year-old male patient was presented with Waldenstrom's Macroglobulinemia, a typical hyperviscosity retinopathy and serous detachment of the macula. We performed fluorescein (FA)- and indocyaningreenangiography (ICG) before and three months after chemotherapy. Especially ICG-angiographic findings revealed a serous detachment that was restricted to the posterior pole but showed a fingershaped enlargement to the optic disc.
  
  
  CONCLUSIONS
  FA- and especially ICG-angiographic findings can help to get more information about the pathogenetic mechanism of serous detachment in Waldenstrom's Macroglobulinemia. Besides toxic alteration of the retinal pigmentepithelium, oncotic and hydrostatic pressure, a pathologic communication between the optic disc, the subarachnoid space and the subretinal space is discussed.
authors.affiliation: Univ. Augenklinik, Graz. beatrix.feigl@kfunigraz.ac.at
authors.forename: B
authors.initials: B
authors.lastname: Feigl
authors.forename: H
authors.initials: H
authors.lastname: Sill
authors.forename: A
authors.initials: A
authors.lastname: Haas
mesh_terms: D000368:Aged; D001809:Blood Viscosity; D004396:Coloring Agents; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D012163:Retinal Detachment / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D008258:Waldenstrom Macroglobulinemia / Q000175:diagnosis*
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green
vernacular_title: Seröse Abhebung der Neuroretina bei Morbus Waldenström. Eine Falldemonstration.