A polyisoprenylated benzophenone from Cuban propolis.
A novel polyisoprenylated benzophenone (1) has been isolated from an ethanol extract of Cuban propolis. Its structure has been determined using high-field 2D NMR techniques. Compound 1 showed significant antimicrobial and antifungal activity against a variety of bacteria and yeasts.
Rubio
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Institute for Pharmacy and Food (IFAL), University of Havana, Ave. 23, 21425, Lisa, C. Habana, Cuba.
Cuellar Cuellar
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Rojas
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Castro
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HV
Rastrelli
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Aquino
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D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification*; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification*; D001419:Bacteria / Q000187:drug effects; D001577:Benzophenones / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D003462:Cuba; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D011429:Propolis / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D015003:Yeasts / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D001577:Benzophenones; C121576:polyisoprenyl benzophenone; D011429:Propolis