title: Peptidyl-prolyl cis-trans isomerases: structure and functions.
abstract: Peptidyl-prolyl cis-trans isomerases (PPI) catalyze cis-trans isomerization of imide bonds in peptides and proteins. This review summarizes the literature on the structure and functions of PPIs, their involvement in protein folding, and organization of PPI-containing receptors and membrane channels. A possible role of several PPIs in distant interactions between cells is discussed.
authors.affiliation: Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117871, Russia. dvor@humgen.siobc.ras.ru
authors.forename: B K
authors.initials: BK
authors.lastname: Pliyev
authors.forename: B Y
authors.initials: BY
authors.lastname: Gurvits
mesh_terms: D000595:Amino Acid Sequence; D008565:Membrane Proteins / Q000378:metabolism; D008958:Models, Molecular; D019696:Peptidylprolyl Isomerase / Q000737:chemistry* / Q000378:metabolism*; D011487:Protein Conformation; D017510:Protein Folding
chemical_list: D008565:Membrane Proteins; D019696:Peptidylprolyl Isomerase