title: Infection due to Absidia corymbifera in a patient with a massive crush trauma of the foot.
abstract: We report the case of a patient with a massive crushing trauma of the right foot who developed a local infection due to Absidia corymbifera. Systemic and local antifungal therapy with ketoconazole associated with hyperbaric oxygen therapy (HBO) yielded a rapid clinical and microbiological resolution. Controlled clinical studies are warranted to further elucidate the potential utility of HBO/antifungal combination therapy.
authors.affiliation: Clinica di Chirurgia Plastica e Ricostruttiva Università degli Studi di Ancona, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Scalise
authors.forename: F
authors.initials: F
authors.lastname: Barchiesi
authors.forename: M A
authors.initials: MA
authors.lastname: Viviani
authors.forename: D
authors.initials: D
authors.lastname: Arzeni
authors.forename: A
authors.initials: A
authors.lastname: Bertani
authors.forename: G
authors.initials: G
authors.lastname: Scalise
mesh_terms: D020095:Absidia / Q000187:drug effects / Q000302:isolation & purification*; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D018409:Foot Injuries / Q000150:complications*; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008826:Microbial Sensitivity Tests; D009091:Mucormycosis / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents