title: [An experience with combined therapy of radiation and Bonephos for osteolytic metastases of breast cancer].
abstract: A new procedure of conservative treatment (radiation + benephos) is suggested to improve the quality of life of cancer patients with osteolytic metastases. Radiation regimen, dosage, benephos administration methods and characteristics of combined therapy are discussed. The procedure was tested in the course of the treatment of 21 breast cancer patients with osteolytic metastases. According to preliminary results, the treatment is easy to tolerate; it produced stable analgetic effect (2-9 months) in 85.7%, as compared with 42.1% in the control group.
authors.affiliation: M.F.Vladimirsky Research Clinical Institute, Ministry of Health of the RF, Moscow Region.
authors.forename: P Iu
authors.initials: PIu
authors.lastname: Poliakov
authors.forename: N A
authors.initials: NA
authors.lastname: Larionova
authors.forename: O A
authors.initials: OA
authors.lastname: Bychenkov
authors.forename: V G
authors.initials: VG
authors.lastname: Moc'kin
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000532:radiotherapy* / Q000556:secondary; D001862:Bone Resorption / Q000150:complications / Q000188:drug therapy / Q000517:prevention & control* / Q000532:radiotherapy; D001943:Breast Neoplasms / Q000473:pathology*; D017024:Chemotherapy, Adjuvant; D004002:Clodronic Acid / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010148:Intractable Pain / Q000188:drug therapy* / Q000209:etiology; D018714:Radiotherapy, Adjuvant; D016896:Treatment Outcome
chemical_list: D018712:Analgesics, Non-Narcotic; D004002:Clodronic Acid
vernacular_title: Opyt sovmestnogo primeneniia luchevoĭ terapii i Bonefosa pri lechenii kostnykh osteoliticheskikh metastazov raka molochnoĭ zhelezy.