title: Patterning the C. elegans embryo: moving beyond the cell lineage.
abstract: The Caenorhabditis elegans embryo undergoes a series of stereotyped cell cleavages that generates the organs and tissues necessary for an animal to survive. Here we review two models of embryonic patterning, one that is lineage-based, and one that focuses on domains of organ and tissue precursors. Our evolving view of C. elegans embryogenesis suggests that this animal develops by mechanisms that are qualitatively similar to those used by other animals.
authors.affiliation: Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, BP163, 67404 Illkirch Cedex, France. lmichel@igbmc.u-strasbg.fr
authors.forename: M
authors.initials: M
authors.lastname: Labouesse
authors.forename: S E
authors.initials: SE
authors.lastname: Mango
mesh_terms: D000818:Animals; D019521:Body Patterning / Q000235:genetics*; D017173:Caenorhabditis elegans / Q000196:embryology*; D019070:Cell Lineage; D004625:Embryo, Nonmammalian / Q000166:cytology; D005775:Gastrula; D013045:Species Specificity