Relation between antibodies to BP180 and gender in bullous pemphigoid.
Bullous pemphigoid is associated with antibodies to 2 basement membrane zone antigens (BP230 and BP180). In some patients antibodies develop to one of these antigens, whereas in others antibodies develop to both. Although the factors behind this are unknown, our study indicates that male gender is one factor.
Jiao
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Department of Dermatology, New York University School of Medicine, New York, 10016, USA.
Bystryn
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JC
D001323:Autoantibodies / Q000032:analysis*; D001324:Autoantigens / Q000276:immunology*; D001485:Basement Membrane / Q000276:immunology; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D008297:Male; D024041:Non-Fibrillar Collagens; D010391:Pemphigoid, Bullous / Q000453:epidemiology / Q000276:immunology*; D012737:Sex Factors; D000097805:Collagen Type XVII
D001323:Autoantibodies; D001324:Autoantigens; D024041:Non-Fibrillar Collagens; D000097805:Collagen Type XVII