Synthesis of novel isomeric dideoxydidehydronucleosides.
Methodologies for the synthesis of novel isomeric dideoxynucleosides with unsaturation in the carbohydrate moiety have been developed. An example of the synthesis (Isod4A) is presented. Antiviral studies are in progress.
Nair
V
V
Department of Chemistry, University of Iowa, Iowa City 52242, USA.
Bera
S
S
Mickle
T
T
Van Calenbergh
S
S
D018360:Crystallography, X-Ray; D015224:Dideoxynucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D007536:Isomerism; D009690:Nucleic Acid Conformation; D013056:Spectrophotometry, Ultraviolet
D015224:Dideoxynucleosides