title: Localization of a ventricular tachycardia-focus with multichannel magnetocardiography and three-dimensional current density reconstruction.
abstract: The objective of this case report is to determine the accurate localization of a malignant ventricular tachycardia (VT) focus by combining multichannel magnetocardiographic (MCG) information with morphologic data. The localization was obtained by calculating the three-dimensional current density distribution (3D-CDD) on the left ventricular surface. To estimate the accuracy of this localization technique, examinations of a healthy volunteer were additionally performed. The MCG-signals were recorded in a magnetically shielded room by a 49-channel magnetogradiometer. The corresponding morphologic information was recorded by magnetic resonance tomography (MRT). The coordinate systems were matched with the help of markers. The 3D-CDD was calculated by the Philips CURRY software package. The origin of a malignant VT determined by X-ray images of the ablation catheter position during the electrophysiological examination (EPE), was used as the gold standard. This was then compared with the localization results obtained by the 3D-CDD. It was found that the localization coordinates showed a difference of less than 10 mm.
authors.affiliation: Department of Cardiology, University Clinic Benjamin Franklin, Free University Berlin, Germany.
authors.forename: H P
authors.initials: HP
authors.lastname: Müller
authors.forename: P
authors.initials: P
authors.lastname: Gödde
authors.forename: K
authors.initials: K
authors.lastname: Czerski
authors.forename: R
authors.initials: R
authors.lastname: Agrawal
authors.forename: G
authors.initials: G
authors.lastname: Feilcke
authors.forename: K
authors.initials: K
authors.lastname: Reither
authors.forename: K J
authors.initials: KJ
authors.lastname: Wolf
authors.forename: M
authors.initials: M
authors.lastname: Oeff
mesh_terms: D000328:Adult; D004562:Electrocardiography; D004594:Electrophysiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008280:Magnetics; D008297:Male; D017180:Tachycardia, Ventricular / Q000175:diagnosis* / Q000503:physiopathology