[Protective activity of 28-kDa 1-Cys peroxiredoxin determines its peroxidase activity].
The 28 kDa peroxiredoxin from rat exhibited peroxidase activity only in the presence of dithiothreitol. Both organic and nonorganic peroxidases were found to be substrates for the 28-kDa peroxiredoxin activity. Analysis of the protective antioxidant activity of the 28-kDa peroxiredoxin revealed that it is accounted for by its peroxidase activity.
Novoselov
V I
VI
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia.
Peshenko
I V
IV
Novoselov
S V
SV
Kamzalov
S S
SS
Bystrova
M F
MF
Evdokimov
V A
VA
Nikolaev
Iu V
IuV
Fesenko
E E
EE
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D004229:Dithiothreitol / Q000378:metabolism; D010544:Peroxidases / Q000378:metabolism*; D054464:Peroxiredoxins; D051381:Rats; D013379:Substrate Specificity
D000975:Antioxidants; D010544:Peroxidases; D054464:Peroxiredoxins; D004229:Dithiothreitol
Protektornaia aktivnost' 28 1-cys peroksiredoksina opredeliaetsia ego peroksidaznoĭ aktivnost'iu.