title: Prevalence and severity of dementia among northern Italian centenarians.
abstract: Using diagnostic criteria from the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders, dementia was clinically diagnosed in 57 (62%) of 92 centenarians living in two northern Italian provinces. The condition was severely disabling in approximately 70% of the demented patients. Although clinically diagnosed AD accounted for 79% of dementia cases, almost one third of patients with AD had risk factors for vascular dementia, suggesting that the aging brain may be susceptible to multiple additive factors that impair cognition.
authors.affiliation: Department of Internal Medicine, Cardioangiology, and Hepatology, S. Orsola-Malpighi Hospital, University of Bologna, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Ravaglia
authors.forename: P
authors.initials: P
authors.lastname: Forti
authors.forename: D
authors.initials: D
authors.lastname: De Ronchi
authors.forename: F
authors.initials: F
authors.lastname: Maioli
authors.forename: B
authors.initials: B
authors.lastname: Nesi
authors.forename: D
authors.initials: D
authors.lastname: Cucinotta
authors.forename: M
authors.initials: M
authors.lastname: Bernardi
authors.forename: G
authors.initials: G
authors.lastname: Cavalli
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D003704:Dementia / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D015995:Prevalence