title: [Amputations and mortality in elderly insulin-treated patients with type 2 diabetes].
abstract: The diabetic foot syndrome has a strong impact on the morbidity of elderly patients with type 2 diabetes, since diabetics have a 22-fold higher amputation rate. The aim of this study was to conduct a prospective evaluation of elderly insulin-treated patients with type 2 diabetes, giving special consideration to the diabetic foot syndrome. 94 consecutively admitted patients (mean age 68 years; mean diabetes duration 13 years) were re-evaluated 2, 5 and 10 years after participation in a 5-day insulin treatment and teaching programme for patients with type 2 diabetes. During the 10-year follow-up period 60 (64%) patients had died. Of the remaining 34 patients 33 were evaluated personally or by phone. All patients still alive had no acute foot complications and no amputations during the 10-year follow-up period. In these patients an acceptable level of metabolic control and acute metabolic decompensations was found. However, in 55 deceased patients (no data were available for 5 patients) 20 above-knee amputations (1 patient on both legs) and 2 fore-foot amputations were performed. This shows that severe complications as amputations associated with high mortality will be grossly underestimated, unless deceased patients are included in follow-up studies. An improved care for the feet of elderly insulin-treated patients is needed.
authors.affiliation: Klinik für Stoffwechselkrankheiten und Ernährung, Heinrich-Heine-Universität Düsseldorf.
authors.forename: M
authors.initials: M
authors.lastname: Spraul
authors.forename: A M
authors.initials: AM
authors.lastname: Schönbach
authors.forename: I
authors.initials: I
authors.lastname: Mühlhauser
authors.forename: M
authors.initials: M
authors.lastname: Berger
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical / Q000401:mortality* / Q000639:trends; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy* / Q000401:mortality*; D017719:Diabetic Foot / Q000209:etiology / Q000401:mortality / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D011446:Prospective Studies; D013577:Syndrome
chemical_list: D007328:Insulin
vernacular_title: Amputationen und Mortalität bei älteren, insulinpflichtigen Patienten mit Typ-2-Diabetes.