title: [Burkholderia mallei and Burkholderia pseudomallei. Study of immuno- and pathogenesis of glanders and melioidosis. Heterologous vaccines].
abstract: Parameters of the infectious activity of B.mallei and B.pseudomallei for animals of various species were determined. Pathomorphological characteristics of the process of malleus and melioidosis were studied on golden hamsters, mice, guinea pigs, rats and monkeys. Tularemia, plague and salmonellosis vaccines were shown to have protective effects in experimental malleus and melioidosis. An insignificant cross immune response between the malleus and melioidosis pathogens was observed.
authors.affiliation: State Research Centre of Applied Microbiology, Obolensk, Moscow Region.
authors.forename: I N
authors.initials: IN
authors.lastname: Manzeniuk
authors.forename: E A
authors.initials: EA
authors.lastname: Galina
authors.forename: V V
authors.initials: VV
authors.lastname: Dorokhin
authors.forename: I Ia
authors.initials: IIa
authors.lastname: Kalachev
authors.forename: V N
authors.initials: VN
authors.lastname: Borzenkov
authors.forename: E A
authors.initials: EA
authors.lastname: Svetoch
mesh_terms: D000818:Animals; D001428:Bacterial Vaccines; D019117:Burkholderia / Q000276:immunology* / Q000472:pathogenicity; D016957:Burkholderia pseudomallei / Q000276:immunology* / Q000472:pathogenicity; D006224:Cricetinae; D005896:Glanders / Q000276:immunology* / Q000382:microbiology; D006168:Guinea Pigs; D008554:Melioidosis / Q000276:immunology* / Q000382:microbiology; D008647:Mesocricetus; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D051381:Rats; D014774:Virulence
chemical_list: D001428:Bacterial Vaccines
vernacular_title: Burkholderia mallei i Burkholderia pseudomallei. Study of immuno- i patogeneza sapa i lemioidoza. Geterologichenye vaktsiny.