title: 7-Hydroxywithanolides from datura ferox
abstract: Three new withanolides were isolated from leaves of Datura ferox. Their structures were established as (17R,20S,22R)-5alpha,6alpha, 7beta,12alpha-tetrahydroxy-1-oxowitha-2,24-dienolide (1), (17R,20S, 22R,24S,25S)-24,25-epoxy-5alpha,6alpha,7beta, 12alpha-tetrahydroxy-1-oxowitha-2-enolide (2), and (17R,20S, 22R)-5alpha,6alpha-epoxy-7alpha-hydroxy-1,12-dioxowitha-2, 24-dienolide (3), using spectroscopic methods (NMR, MS) and molecular modeling.
authors.affiliation: Departamento de Quimica Organica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellon 2, Ciudad Universitaria, (1428) Buenos Aires, and Departamento de Quimica Organica and IMBIV (CONICET), Facultad de Cie.
authors.initials: AS
authors.lastname: Veleiro
authors.initials: AM
authors.lastname: Cirigliano
authors.initials: JC
authors.lastname: Oberti
authors.initials: G
authors.lastname: Burton