title: [Acute lung injury as initial manifestation of diffuse alveolar hemorrhage].
abstract: OBJECTIVE
  To determine clinical features and outcome in hospitalized patients with acute lung injury secondary to diffuse pulmonary hemorrhage (DPH).
  
  
  METHODS
  Eight adult patients suffering DPH and acute lung injury were undergone to diagnosis procedure and following.
  
  
  RESULTS
  Two cases of idiopathic pulmonary hemosiderosis, two cases of systemic lupus erythematous, two cases of Goodpasture's syndrome, one case of idiopathic rapidly progressive glomerulonephritis and one of periarteritis nodosa were diagnosed. Treatment was methylprednisolone in all cases; besides, three cases required ventilatory support, and one immunosuppressive therapy, plasmapheresis and hemodialysis. One patient died and three of them suffered relapse with satisfactory outcome.
  
  
  CONCLUSIONS
  We remark the presence of acute lung injury as an initial feature of DPH in our experience and the importance of a prompt diagnosis of the underlying disease.
authors.affiliation: Servicio de Neumología, Hospital Dr. Peset, Valencia.
authors.forename: E
authors.initials: E
authors.lastname: Fernández Fabrellas
authors.forename: J
authors.initials: J
authors.lastname: Blanquer Olivas
authors.forename: R
authors.initials: R
authors.lastname: Blanquer Olivas
authors.forename: M
authors.initials: M
authors.lastname: Simó Mompó
authors.forename: E
authors.initials: E
authors.lastname: Chiner Vives
authors.forename: F
authors.initials: F
authors.lastname: Ruiz Montalt
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D019867:Anti-Glomerular Basement Membrane Disease / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D005921:Glomerulonephritis / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D006470:Hemorrhage / Q000175:diagnosis / Q000209:etiology*; D006486:Hemosiderosis / Q000150:complications / Q000175:diagnosis; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis / Q000209:etiology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D010956:Plasmapheresis; D010488:Polyarteritis Nodosa / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D011650:Pulmonary Alveoli; D006435:Renal Dialysis
chemical_list: D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone
vernacular_title: Daño pulmonar agudo como manifestación inicial de hemorragia alveolar difusa.