title: Interferon beta-1b and childhood multiple sclerosis.
abstract: The long-term treatment with interferon beta-1b of a 7-year-old male with relapsing-remitting multiple sclerosis is documented. Thirty-two months after initiating treatment, he demonstrates dramatic clinical improvement, without relapse, despite high titers of neutralizing antibodies to interferon beta-1b. It appears reasonable to attribute a role in his improvement to interferon beta-1b.
authors.affiliation: College of Medicine, Department of Neurology, Medical University of South Carolina, Charleston, USA.
authors.forename: A B
authors.initials: AB
authors.lastname: Adams
authors.forename: W R
authors.initials: WR
authors.lastname: Tyor
authors.forename: K R
authors.initials: KR
authors.lastname: Holden
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D002648:Child; D004334:Drug Administration Schedule; D005684:Gait; D006801:Humans; D016899:Interferon-beta / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000188:drug therapy*; D012008:Recurrence; D016896:Treatment Outcome; D014785:Vision, Ocular
chemical_list: D000276:Adjuvants, Immunologic; D016899:Interferon-beta