title: [Acute pernicious malaria treated with exchange transfusion].
abstract: A 53-year-old patient, after return from a short visit to the Ivory Coast, was admitted for suspicion of hepatic encephalopathy. An acute pernicious malaria was diagnosed with associating altered consciousness, hyperthermia, icterus, hepatomegaly, and oliguria. Blood tests showed acute renal failure, pancytopenia, disseminated intravascular coagulation, metabolic acidosis and parasitaemia at 12%. An intravenous therapy with quinine and doxycycline was started without delay. One day later, an exchange blood transfusion including a erythrapheresis and plasmapheresis was undertaken. The patient's general condition improved, and he was discharged from the ICU 22 days later. The indications for exchange blood transfusion in acute pernicious malaria are discussed.
authors.affiliation: Département d'anesthésie-réanimation, hôpital de l'Hôtel-Dieu, Lyon, France.
authors.forename: L
authors.initials: L
authors.lastname: Mathon
authors.forename: C A
authors.initials: CA
authors.lastname: Recoque
authors.forename: B
authors.initials: B
authors.lastname: Allaouchiche
authors.forename: D
authors.initials: D
authors.lastname: Chassard
mesh_terms: D000208:Acute Disease; D003422:Critical Care; D017707:Erythrocyte Transfusion; D005078:Exchange Transfusion, Whole Blood; D006801:Humans; D016779:Malaria, Cerebral / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis
vernacular_title: Accès pernicieux palustre traité par exsanguino-transfusion.