[The hemodynamic changes after end-to-end anastomosis of the small arteries in rats].
The hemodynamics changes of the common carotid arteries in 10 SD rats were measured with a color doppler flowmetry in an attempt to define the changes resulting from end-to-end anastomosis. The left common carotid arteries were divided and followed by end-to-end anastomosis. The systolic mean peak velocities in the left arteries were measured at the proximal, distal and anastomotic sites and in the right intact arteries as well at 6, 12, 24, 48, 72 and 120 hours after repair. The percentage of area reduction at anastomosis was calculated from these data. The results indicated that the systolic mean peak velocity at the anastomotic sites was significantly increased as compared to the velocity at the proximal, distal and contralateral sites (P < 0.05). The velocity at the distal sites was significantly lower than that from the proximal and contralateral sites (P < 0.05), the mean percentage of the reduction was 33.18% and 33.33%, respectively. From 6 hours to 120 hours after anastomosis of arteries there was various degree of narrowing at the site of anastomosis. The mean per cent of stenosis was 42.48%. It was concluded that from 6 to 120 hours after end-to-end anastomosis of the small arteries, the velocity at the anastomotic site was increased as compared to the velocities at pre- and post-anastomotic sites. The increase of velocity at the site of anatomosis was caused by stenosis at the anastomosis.
An
Z
Z
Department of Hand Surgery, Huashan Hospital, Shanghai Medical University, P.R. China.
Gu
Y
Y
Wang
Y
Y
D000714:Anastomosis, Surgical / Q000009:adverse effects; D000818:Animals; D001783:Blood Flow Velocity; D020212:Carotid Artery Injuries / Q000601:surgery*; D017536:Carotid Artery, Common / Q000601:surgery*; D016893:Carotid Stenosis / Q000209:etiology; D006439:Hemodynamics; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors