title: A new device to quantify regenerate torsional stiffness in distraction osteogenesis.
abstract: We present a newly developed torsional stiffness measurement device with the potential to quantitatively assess the in vivo torsional stiffness of bone regenerate during distraction osteogenesis. We describe the form and function of this device and its application in a model of regenerate consolidation. The device was able to produce data to assess stiffness of the regenerate with an accuracy between +/- 3 and +/- 9% for material stiffness ranging between 0.1 and 2.4 Nm/o and with a precision of +/- 3.6%. This method provides advantages over similar methods of bone fracture healing assessment with guaranteed maintenance of bone axis, minimized risk of bone misalignment during the bone healing process and a close relation to the functional loading pattern in torsion of bones such as tibia and femora.
authors.affiliation: Department of Trauma Surgery, Virchow Klinikum, Humboldt-University, Berlin, Germany. windhagen@annastift.de
authors.forename: H
authors.initials: H
authors.lastname: Windhagen
authors.forename: H
authors.initials: H
authors.lastname: Bail
authors.forename: A
authors.initials: A
authors.lastname: Schmeling
authors.forename: S
authors.initials: S
authors.lastname: Kolbeck
authors.forename: A
authors.initials: A
authors.lastname: Weiler
authors.forename: M
authors.initials: M
authors.lastname: Raschke
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001861:Bone Regeneration / Q000502:physiology*; D004548:Elasticity; D004867:Equipment Design; D006801:Humans; D008422:Materials Testing; D008954:Models, Biological; D015588:Observer Variation; D010012:Osteogenesis / Q000502:physiology*; D019857:Osteogenesis, Distraction / Q000295:instrumentation* / Q000379:methods; D015203:Reproducibility of Results; D013314:Stress, Mechanical