title: Steroids from the roots of Nerium oleander.
abstract: Two new cardenolides, 3beta-hydroxy-5alpha-carda-14(15), 20(22)-dienolide (beta-anhydroepidigitoxigenin) (1) and 3beta-O-(D-digitalosyl)-21-hydroxy-5beta-carda-8,14,16 , 20(22)-tetraenolide (neriumogenin-A-3beta-D-digitaloside) (2), and two known compounds, proceragenin and neridienone A (3), have been isolated from the roots of Nerium oleander. The structures of 1 and 2 were elucidated on the basis of spectral data interpretation.
authors.affiliation: Phytochemical Research Laboratory, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
authors.forename: M M
authors.initials: MM
authors.lastname: Huq
authors.forename: A
authors.initials: A
authors.lastname: Jabbar
authors.forename: M A
authors.initials: MA
authors.lastname: Rashid
authors.forename: C M
authors.initials: CM
authors.lastname: Hasan
authors.forename: C
authors.initials: C
authors.lastname: Ito
authors.forename: H
authors.initials: H
authors.lastname: Furukawa
mesh_terms: D002240:Carbohydrate Sequence; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013256:Steroids / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D013256:Steroids; C121588:beta-anhydroepidigitoxigenin; C121589:neriumogenin-A-digitaloside