Conformal radiation therapy treatment planning reduces the dose to the optic structures for patients with tumors of the paranasal sinuses.
OBJECTIVE
Compare dose distributions of traditional versus conformal beam orientations in paranasal sinus malignancies.


METHODS
Maximum normal tissue doses, dose volume histograms (DVH), normal tissue complication probabilities (NTCP), and the percentage of each normal tissue receiving >80% of the average target dose (V80) were calculated.


CONCLUSIONS
Conformal planning reduced the V80 to the optic nerves and chiasm as well as the normal tissue maximum doses to the ipsilateral and contralateral optic nerves and chiasm, and mean NTCPs.
Brizel
D M
DM
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.
Light
K
K
Zhou
S M
SM
Marks
L B
LB
D005005:Ethmoid Sinus; D006801:Humans; D008444:Maxillary Sinus Neoplasms / Q000532:radiotherapy; D009897:Optic Chiasm; D009900:Optic Nerve; D010255:Paranasal Sinus Neoplasms / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000517:prevention & control; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods; D020266:Radiotherapy, Conformal / Q000009:adverse effects / Q000379:methods*