title: [The separate and combined use of timoptic depot].
abstract: Study of the efficacy of a new long-acting drug timoptic depot (timolol maleate) in 15 patients demonstrated its manifest hypotensive effect. Its administration once a day regulates the level of ophthalmic tone. If additional therapy was needed during treatment with timoptic depot, the best results (more pronounced effect on ophthalmic tone and best tolerance) were observed with combinations of the drug with trusopt or glaucone. Like other nonselective beta-blockers, timoptic depot may cause intraventricular conductivity of the myocardium and sinusoidal bradycardia.
authors.forename: E A
authors.initials: EA
authors.lastname: Egorov
authors.forename: T V
authors.initials: TV
authors.lastname: Stavitskaia
authors.forename: S P
authors.initials: SP
authors.lastname: Voĭtova
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage* / Q000009:adverse effects; D000959:Antihypertensive Agents / Q000008:administration & dosage* / Q000009:adverse effects; D003692:Delayed-Action Preparations; D004359:Drug Therapy, Combination; D005902:Glaucoma, Open-Angle / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D012996:Solutions; D013997:Time Factors; D013999:Timolol / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D003692:Delayed-Action Preparations; D012996:Solutions; D013999:Timolol
vernacular_title: Izuchenie razdel'nogo i kombinirovannogo primeneniia timoptika-depo.