title: Evaluation of a screening program on reduction of gastric cancer mortality in Japan: preliminary results from a cohort study.
abstract: BACKGROUND
  Systematic population-based screening for gastric cancer is widely spread in Japan. However, the case-control study method has been the main method used to evaluate the effectiveness of the screen ing to reduce gastric cancer mortality in Japan.
  
  
  METHODS
  This article presents a population-based cohort study. A questionnaire about lifestyles and dietary habits was distributed to 36,990 residents in a city of Japan. The response rate to the questionnaire was 92.0%. After ineligible responders had been excluded, 24,134 subjects were classified into screened and un screened groups according to their self-reports of participation in the screening the previous year. We followed them up for 40 months and linked resident death records in the city. We compared mortality from gastric cancer and all other causes between the groups by us ing the Cox proportional hazard model.
  
  
  RESULTS
  The follow-up period was 78,156.6 person-years from September 1992 to December 1995. The multivariate relative risks for gastric cancer death of the screened group in comparison with the unscreened group were 0.72 (95% CI 0.31-1.66) among males and 1.46 (95% CI 0.43-4.90) among females.
  
  
  CONCLUSIONS
  Although our data are preliminary, we were unable to demonstrate a large contribution of the present screening program to decreasing gastric cancer mortality. Further follow-up is needed to in crease the precision.
authors.affiliation: Department of Public Health, Gifu University School of Medicine, 40 Tsukasa-machi, Gifu, 500-8705, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Inaba
authors.forename: H
authors.initials: H
authors.lastname: Hirayama
authors.forename: C
authors.initials: C
authors.lastname: Nagata
authors.forename: Y
authors.initials: Y
authors.lastname: Kurisu
authors.forename: N
authors.initials: N
authors.lastname: Takatsuka
authors.forename: N
authors.initials: N
authors.lastname: Kawakami
authors.forename: H
authors.initials: H
authors.lastname: Shimizu
mesh_terms: D000328:Adult; D000368:Aged; D002423:Cause of Death; D018672:Community Health Planning; D015986:Confounding Factors, Epidemiologic; D003644:Death Certificates; D005247:Feeding Behavior; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008019:Life Style; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D015999:Multivariate Analysis; D015397:Program Evaluation; D016016:Proportional Hazards Models; D012107:Research Design; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000401:mortality* / Q000517:prevention & control*; D011795:Surveys and Questionnaires