ClC channels: leaving the dark ages on the verge of a new millennium.
The field of molecular physiology of ClC chloride channels has witnessed a tremendous surge in knowledge over the past few years; however, fundamental issues such as the stoichiometry of ClC channels and the identification of pore-lining sequences have only recently begun to be addressed. New studies have also provided important insights into the role of ClC channels in cell volume regulation and their function in intracellular organelles.
Valverde
M A
MA
Department de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, C/Dr. Aiguader 80, 08003, Barcelona, Spain. miguel.valverde@cexs.upf.es
D000818:Animals; D018118:Chloride Channels / Q000502:physiology*; D006801:Humans; D007425:Intracellular Membranes; D015640:Ion Channel Gating
D018118:Chloride Channels; C115376:ClC-3 channel