title: Tumor staging of pancreatic adenocarcinoma using early- and late-phase helical CT.
abstract: OBJECTIVE
  We compared early-phase CT with late-phase CT in the evaluation of pancreatic adenocarcinoma.
  
  
  METHODS
  Both early- and late-phase CT images of 25 pancreatic adenocarcinomas were compared with surgical-pathologic findings. We evaluated tumor detectability, tumor size, and local tumor invasion.
  
  
  RESULTS
  Tumor detectability was 96% on early-phase CT imaging and 64% on late-phase CT imaging (p < .01). Sensitivity for anterior serosal invasion, retroperitoneal invasion, and arterial invasion on early-phase CT exceeded sensitivity on late-phase CT (p < .05). However, specificity for all factors on early-phase CT was less than or equal to specificity on late-phase CT. The grade of local tumor invasion on early-phase CT achieved better agreement with the surgical-pathologic results than did late-phase CT, especially for tumor size and retroperitoneal invasion.
  
  
  CONCLUSIONS
  Early-phase CT was better than late-phase CT in revealing tumors, tumor size, and retroperitoneal invasion.
authors.affiliation: Department of Nuclear Medicine and Diagnostic Imaging, Graduate School of Medicine, Kyoto University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Tabuchi
authors.forename: K
authors.initials: K
authors.lastname: Itoh
authors.forename: G
authors.initials: G
authors.lastname: Ohshio
authors.forename: N
authors.initials: N
authors.lastname: Kojima
authors.forename: Y
authors.initials: Y
authors.lastname: Maetani
authors.forename: T
authors.initials: T
authors.lastname: Shibata
authors.forename: J
authors.initials: J
authors.lastname: Konishi
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D000368:Aged; D018196:Carcinoma, Adenosquamous / Q000000981:diagnostic imaging* / Q000473:pathology*; D018282:Cystadenocarcinoma, Mucinous / Q000000981:diagnostic imaging* / Q000473:pathology*; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010179:Pancreas / Q000000981:diagnostic imaging / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D012680:Sensitivity and Specificity; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods* / Q000706:statistics & numerical data