title: What is reflex sympathetic dystrophy?
abstract: In the literature there is no unanimity with respect to the diagnosis of reflex sympathetic dystrophy (RSD). Frequently, the diagnosis is established on mere clinical grounds. In our opinion, however, bone scintigraphy is of major importance for the diagnosis. Using this examination, true RSD can be clearly differentiated from other conditions which are incorrectly diagnosed and treated as RSD. If the bone scan is not suggestive of RSD, the clinical picture, radiological examination and vascular scan may lead to the correct diagnosis. This may be a pseudodystrophy, in which a hypovascularization is found right from the start, while in true RSD there is initially a hypervascularization. Other conditions which may be confused with RSD are causalgia, neurotic compulsive postures, hysterical conversion, malingering and even self-mutilation. In the spontaneous course of RSD three phases can be distinguished. Stage I is the warm or hypertrophic phase, stage II the cold or atrophic phase. Per definition the third phase corresponds to stabilization or, in rare instances, to healing. By means of the vascular scan the correct stage can be determined, and the results of treatment evaluated. Finally it should be noted that in children the condition is completely different from true RSD, as it concerns a pseudodystrophy or disuse-related dystrophy. This condition may also be seen in adults and adolescents, usually females. The bone scan is always negative. In this way bone scintigraphy constitutes the means to answer the question as to what RSD is and what it is not. An algorithm for the differential diagnosis is presented.
authors.affiliation: University Hospital Antwerp, Department of Physical Medicine, Edegem, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Driessens
authors.forename: H
authors.initials: H
authors.lastname: Dijs
authors.forename: G
authors.initials: G
authors.lastname: Verheyen
authors.forename: P
authors.initials: P
authors.lastname: Blockx
mesh_terms: D000293:Adolescent; D000328:Adult; D001284:Atrophy; D001842:Bone and Bones / Q000098:blood supply / Q000000981:diagnostic imaging; D002422:Causalgia / Q000175:diagnosis; D002648:Child; D003193:Compulsive Personality Disorder / Q000175:diagnosis; D003286:Contracture / Q000175:diagnosis; D003291:Conversion Disorder / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006984:Hypertrophy; D011877:Radionuclide Imaging; D012019:Reflex Sympathetic Dystrophy / Q000145:classification / Q000175:diagnosis* / Q000000981:diagnostic imaging; D012652:Self Mutilation / Q000175:diagnosis; D014652:Vascular Diseases / Q000000981:diagnostic imaging