title: Adolescent reproductive events and subsequent breast cancer risk.
abstract: OBJECTIVE
  This study investigated the relationship between reproductive events during adolescence and subsequent breast cancer risk.
  
  
  METHODS
  Logistic regression models used self-reported data from 862 case patients and 790 controls in the Carolina Breast Cancer Study.
  
  
  RESULTS
  Miscarriage, induced abortion, and full-term pregnancy before 20 years of age were not associated with breast cancer. Among premenopausal women, breast-feeding before 20 years of age was inversely associated with disease. Oral contraceptive use before 18 years of age was positively associated with disease risk among African American women only.
  
  
  CONCLUSIONS
  Pregnancy during adolescence does not appear to influence breast cancer risk, but breast-feeding may. A possible increased breast cancer risk among African American women who used oral contraceptives as adolescents warrants further study.
authors.affiliation: Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892-7354, USA. pm145q@nih.gov
authors.forename: P M
authors.initials: PM
authors.lastname: Marcus
authors.forename: D D
authors.initials: DD
authors.lastname: Baird
authors.forename: R C
authors.initials: RC
authors.lastname: Millikan
authors.forename: P G
authors.initials: PG
authors.lastname: Moorman
authors.forename: B
authors.initials: B
authors.lastname: Qaqish
authors.forename: B
authors.initials: B
authors.lastname: Newman
mesh_terms: D000293:Adolescent; D000328:Adult; D001942:Breast Feeding / Q000009:adverse effects; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000517:prevention & control; D016022:Case-Control Studies; D003276:Contraceptives, Oral / Q000009:adverse effects; D005260:Female; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D016017:Odds Ratio; D011247:Pregnancy; D011253:Pregnancy in Adolescence; D017584:Reproductive History; D012307:Risk Factors
chemical_list: D003276:Contraceptives, Oral