The impact of residual renal function and total body water volume on achieving adequate dialysis in CAPD.
OBJECTIVE
The objective is to evaluate the impact of residual renal function (RRF) and total body water (TBW) on achieving adequate dialysis.


METHODS
Sixty three CAPD patients performing four 2 liter exchanges daily were evaluated for RRF, total weekly Kt/V (TWKt/V), total weekly creatinine clearance (TWCC) and TBW.


RESULTS
In patients with residual renal function (N = 41), TWKt/V and TWCC were 2.2 +/- 0.8 and 77.4 +/- 24.5 L, respectively. In patients without RRF (N = 22), TWKt/V was 1.6 +/- 0.4 and TWCC 42.6 +/- 9.2 L. TBW correlated negatively with TWKt/V in the group without RRF (r = -0.75, P<0.001).


CONCLUSIONS
It is not possible for larger patients without RRF treated with CAPD (2L x 4 exchanges) to achieve the acceptable targets for TWKt/V and TWCC due to TBW.
Gao
H
H
Department of Medicine, The George Washington University Medical Center, Washington, DC 20037, USA.
Lew
S Q
SQ
Ronco
C
C
Mishkin
G J
GJ
Bosch
J P
JP
D000328:Adult; D000368:Aged; D001834:Body Water; D003404:Creatinine / Q000378:metabolism; D006801:Humans; D007668:Kidney / Q000502:physiology*; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory
D003404:Creatinine