title: [Experimental study of long-term result from reconstruction of vertebral artery].
abstract: Occlusive disease of first segment of vertebral artery is the common cause for insufficient supply of vertebro-basilar artery. The good result following reconstruction of vertebral artery was confirmed, but the long-term result was not certain. In order to investigate the long-term result, 23 dogs with established model of VA occlusion were studied. The occlusion was reconstructed by a by-pass operation between the common carotid artery and VA, then the quantitative methods were used to monitor the results for 3 months following operation. The results showed that 1. according to DSA, the anastomosis remained potent and the collateral circulations were established; 2. the hemodynamics of blood flow in VA kept well and the blood supply was stable by color ultrasonic Doppler; 3. the blood supply of cerebellum was increased 15.86% compared with that observed just after operation by hydrogen clearance method; and 4. no infarction focus was founded from MRI. The conclusion was that the result suggested that the long term result demonstrated was satisfactory after VA reconstruction for occlusive disease and the blood supply of the cerebellum was also better than that just following operation.
authors.affiliation: Peripheral Vessels Research Laboratory, Second Affiliated Hospital, Suzhou Medical College, Jiangsu, P.R. China.
authors.forename: Y
authors.initials: Y
authors.lastname: Sun
authors.forename: Z
authors.initials: Z
authors.lastname: Shen
authors.forename: Y
authors.initials: Y
authors.lastname: Zhen
mesh_terms: D000818:Animals; D017536:Carotid Artery, Common / Q000601:surgery*; D002531:Cerebellum / Q000098:blood supply; D002560:Cerebrovascular Circulation; D004285:Dogs; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics; D008297:Male; D019651:Plastic Surgery Procedures / Q000379:methods; D014656:Vascular Surgical Procedures; D014711:Vertebral Artery / Q000601:surgery*; D014715:Vertebrobasilar Insufficiency / Q000601:surgery*