title: Synthesis of a new analog of thymidine for in vivo non-radioactive labeling of DNA.
abstract: The introduction of 6-(p-bromobenzoylamino)caproyl radical in the methyl group of 2'-O-deoxythymidine is described. In vivo incorporation of this nucleoside to DNA was determined using a monoclonal antibody that recognized the radical.
authors.affiliation: Organic Chemistry Department, National Center for Scientific Research, Havana, Cuba.
authors.forename: C
authors.initials: C
authors.lastname: Rodríguez-Tanty
authors.forename: R
authors.initials: R
authors.lastname: Pérez
authors.forename: J
authors.initials: J
authors.lastname: Miranda
authors.forename: H
authors.initials: H
authors.lastname: Vélez-Castro
authors.forename: A
authors.initials: A
authors.lastname: Rosado
authors.forename: A
authors.initials: A
authors.lastname: Macías
authors.forename: L
authors.initials: L
authors.lastname: Galán
authors.forename: D
authors.initials: D
authors.lastname: Higginson-Clarke
authors.forename: A M
authors.initials: AM
authors.lastname: Riverón
mesh_terms: D004269:DNA, Bacterial / Q000737:chemistry*; D004926:Escherichia coli / Q000235:genetics; D009682:Magnetic Resonance Spectroscopy; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013936:Thymidine / Q000031:analogs & derivatives* / Q000138:chemical synthesis
chemical_list: D004269:DNA, Bacterial; D013936:Thymidine