title: Lectin production by human T-lymphocytes.
abstract: Cultured human peripheral blood monocytes (PBMC) and the cell line H9 release a lectin. This lectin is not the previously described sarcolectin, since it does not specifically recognize the sugars lactose and sialic acid. The lectinic T-cell factor reduces the release by APCs of IFN alpha--a key cytokine known to inhibit the proliferation of activated T-lymphocytes.
authors.forename: A
authors.initials: A
authors.lastname: Lachgar
authors.forename: H
authors.initials: H
authors.lastname: Le Buanec
authors.forename: A
authors.initials: A
authors.lastname: Burny
authors.forename: B
authors.initials: B
authors.lastname: Bizzini
authors.forename: D
authors.initials: D
authors.lastname: Zagury
mesh_terms: D000371:Agglutination; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology; D000938:Antigen-Presenting Cells / Q000378:metabolism; D002460:Cell Line; D016895:Culture Media, Serum-Free; D006801:Humans; D016898:Interferon-alpha / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D037102:Lectins / Q000378:metabolism*; D008937:Mitomycins / Q000494:pharmacology; D013601:T-Lymphocytes / Q000378:metabolism*
chemical_list: D000903:Antibiotics, Antineoplastic; D016895:Culture Media, Serum-Free; D016898:Interferon-alpha; D037102:Lectins; D008937:Mitomycins