[Effects of endogenous beta-adrenoceptor agonist on lung edema in scalded rats].
The effect of endogenous beta-adrenoceptor agonist on lung edema in scalded rats were investigated. The results showed that lung water content, wet/dry lung weight ration, bronchoalveolar lavage (BAL) protein concentration, malondialdehyde (MDA) content and leukocyte count in scalded and PPN treated rats were obviously higher than hose in control rats. The above parameters in scalded rats pretreated with PPN were even much higher than those of control and tended to be higher than burn group. It is suggested that endogenous beta-agonist is effective in the prevention of lung edema and lipid peroxidation, and it acts as an important anti-inflammatory factor in vivo.
Jiang
M
M
Department of Nursing, Second Military Medical University, Shanghai.
Li
S
S
Zhang
Y
Y
D000318:Adrenergic beta-Agonists; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry; D002056:Burns / Q000150:complications / Q000378:metabolism*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D011433:Propranolol / Q000494:pharmacology*; D011654:Pulmonary Edema / Q000209:etiology / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley
D000318:Adrenergic beta-Agonists; D000319:Adrenergic beta-Antagonists; D008315:Malondialdehyde; D011433:Propranolol