[Serous detection of the neuroretina in Waldenström disease. A case report].
BACKGROUND
Waldenstrom's Macroglobulinemia is a monoclonal gammopathy producing pathologic IgM antibodies with increased blood viscosity, platelet dysfunction and retinal hemorrhages. As a complication a serous detachment of the macula is described. The pathogenesis of the serous detachment is still not fully understood.


METHODS
A 73-year-old male patient was presented with Waldenstrom's Macroglobulinemia, a typical hyperviscosity retinopathy and serous detachment of the macula. We performed fluorescein (FA)- and indocyaningreenangiography (ICG) before and three months after chemotherapy. Especially ICG-angiographic findings revealed a serous detachment that was restricted to the posterior pole but showed a fingershaped enlargement to the optic disc.


CONCLUSIONS
FA- and especially ICG-angiographic findings can help to get more information about the pathogenetic mechanism of serous detachment in Waldenstrom's Macroglobulinemia. Besides toxic alteration of the retinal pigmentepithelium, oncotic and hydrostatic pressure, a pathologic communication between the optic disc, the subarachnoid space and the subretinal space is discussed.
Feigl
B
B
Univ. Augenklinik, Graz. beatrix.feigl@kfunigraz.ac.at
Sill
H
H
Haas
A
A
D000368:Aged; D001809:Blood Viscosity; D004396:Coloring Agents; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D012163:Retinal Detachment / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D008258:Waldenstrom Macroglobulinemia / Q000175:diagnosis*
D004396:Coloring Agents; D007208:Indocyanine Green
Seröse Abhebung der Neuroretina bei Morbus Waldenström. Eine Falldemonstration.