[Changes in energy metabolism and the efficacy of drug correction in epilepsy].
A comparative evaluation of intensity of energy exchange and of oxidative phosphorylation showed that disorganization of energy exchange plays a part in the pathogenesis of epilepsy, with the activity of energy enzymes and oxidative phosphorylation being upset in decompensation of the malady. In consideration of the effectiveness of treatment aimed at normalizing energy exchange in epileptic patients it can be regarded as justifiable to initiate regular course treatment capable of influencing the state of energy exchange in decompensation of the illness induced by an exogenous factor, as well as a prophylactic course treatment, with the biochemical parameters being studied in a time-related fashion.
Dubenko
A Ie
AIe
D000244:Adenosine Diphosphate / Q000097:blood; D000255:Adenosine Triphosphate / Q000097:blood; D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D004569:Electroencephalography / Q000187:drug effects; D004734:Energy Metabolism / Q000187:drug effects*; D004827:Epilepsy / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D008875:Middle Aged; D010085:Oxidative Phosphorylation / Q000187:drug effects
D000927:Anticonvulsants; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate
Zminy enerhetychnoho obminu ta efektyvnist' medykamentoznoï korektsiï pry epilepsiï.