title: Oncospheres of Taenia solium and T. saginata asiatica develop into metacestodes in normal and immunosuppressed mice.
abstract: Normal and immunosuppressed mice were infected with oncospheres of Taenia saginata asiatica and T. solium. Although normal ICR mice were not susceptible to these two parasites, cysticerci were recovered from the immunosuppressed ones following venous injection. For T. s. asiatica, immunosuppressed ICR mice had an infection rate of 12.5% and six cysticerci of this parasite were recovered from three males. After injection of T. solium oncospheres, a high infection rate of 57% was obtained and 23 cysticerci were collected from 13 male immunosuppressed ICR mice. The immunosuppressed C57 mice had the highest infection rate (100%) and cysticercus recovery rate (2.4%) for T. solium. The infection rate and cysticercus recovery rate in six normal C57 mice were 40% and 3% respectively. The immunosuppressed ICR, Balb/c and C3H mice were also susceptible to T. s. asiatica.
authors.affiliation: Institute of Parasitology, National Yangming University, Taipei, Taiwan, Republic of China.
authors.forename: I C
authors.initials: IC
authors.lastname: Wang
authors.forename: Y X
authors.initials: YX
authors.lastname: Ma
authors.forename: J X
authors.initials: JX
authors.lastname: Guo
authors.forename: W C
authors.initials: WC
authors.lastname: Chung
authors.forename: S C
authors.initials: SC
authors.lastname: Lu
authors.forename: A
authors.initials: A
authors.lastname: Ito
authors.forename: P C
authors.initials: PC
authors.lastname: Fan
mesh_terms: D000818:Animals; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D007108:Immune Tolerance; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008813:Mice, Inbred ICR; D013045:Species Specificity; D013621:Taenia / Q000254:growth & development* / Q000302:isolation & purification; D013622:Taeniasis / Q000276:immunology* / Q000469:parasitology