Fulminant hepatic failure caused by adenovirus infection following bone marrow transplantation for Hodgkin's disease.
Adenoviruses are increasingly realised to be responsible for serious morbidity and mortality following allogeneic bone marrow transplantation. We describe a case of fulminant hepatic failure due to adenovirus serotype 2 in a 39-year-old woman who received a matched sibling allogeneic bone marrow transplant for multiply relapsed Hodgkin's disease. Isolated fulminant hepatic failure caused by this serotype of adenovirus has not previously been described.
Somervaille
T C
TC
Department of Haematology, University College Hospital, London, UK.
Kirk
S
S
Dogan
A
A
Landon
G V
GV
Mackinnon
S
S
D000257:Adenoviridae Infections / Q000150:complications* / Q000473:pathology; D000260:Adenoviruses, Human; D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects* / Q000473:pathology; D005260:Female; D006501:Hepatic Encephalopathy / Q000209:etiology* / Q000473:pathology / Q000821:virology; D006689:Hodgkin Disease / Q000473:pathology / Q000628:therapy* / Q000821:virology; D006801:Humans