title: An economical synthesis of famciclovir.
abstract: An economical synthesis of famciclovir from N-2-acetyl-7-benzylguanine by a novel regioselective alkylation with the diester cyclopropane compound was developed.
authors.affiliation: AminoScience Laboratories, Ajinomoto Co. Inc., Kawasaki, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hijiya
authors.forename: K
authors.initials: K
authors.lastname: Yamashita
authors.forename: M
authors.initials: M
authors.lastname: Kojima
authors.forename: Y
authors.initials: Y
authors.lastname: Uchida
authors.forename: S
authors.initials: S
authors.lastname: Katayama
authors.forename: T
authors.initials: T
authors.lastname: Torii
authors.forename: H
authors.initials: H
authors.lastname: Shiragami
authors.forename: K
authors.initials: K
authors.lastname: Izawa
mesh_terms: D015075:2-Aminopurine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D000998:Antiviral Agents / Q000138:chemical synthesis*; D003365:Costs and Cost Analysis; D000077595:Famciclovir
chemical_list: D000998:Antiviral Agents; D015075:2-Aminopurine; D000077595:Famciclovir