title: Beta-amyloid: Alzheimer's disease and brain beta-amyloidoses.
abstract: This review considers some aspects of the biochemistry of beta-amyloid, a protein which produces insoluble deposits in the brain. These deposits are a specific morphological feature of Alzheimer's disease, Down's syndrome, and senile dementia. Our contribution to the concept of a soluble form of beta-amyloid as of a normal human protein is presented.
authors.affiliation: Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, 119832, Russia. inst@ibmh.msk.su
authors.forename: N V
authors.initials: NV
authors.lastname: Koudinova
authors.forename: T T
authors.initials: TT
authors.lastname: Berezov
authors.forename: A R
authors.initials: AR
authors.lastname: Koudinov
mesh_terms: D000544:Alzheimer Disease / Q000378:metabolism*; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D000686:Amyloidosis / Q000378:metabolism*; D006801:Humans
chemical_list: D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor