title: Synthesis of isoxazolidino analogues of 2',3'-dideoxynucleosides.
abstract: The complete set of the 4'-aza analogues of 2',3'-dideoxynucleosides was synthesized by cycloaddition of N-tetrahydropiranyl or N-trityl methylene nitrones on suitably protected vinyl nucleobases. The convertible nucleoside approach was used in the preparation of cytosine and 5-methyl cytosine analogues.
authors.affiliation: Dipartimento di Chimica, Università della Calabria.
authors.forename: E
authors.initials: E
authors.lastname: Colacino
authors.forename: A
authors.initials: A
authors.lastname: Converso
authors.forename: A
authors.initials: A
authors.lastname: De Nino
authors.forename: A
authors.initials: A
authors.lastname: Leggio
authors.forename: A
authors.initials: A
authors.lastname: Liguori
authors.forename: L
authors.initials: L
authors.lastname: Maiuolo
authors.forename: A
authors.initials: A
authors.lastname: Napoli
authors.forename: A
authors.initials: A
authors.lastname: Procopio
authors.forename: C
authors.initials: C
authors.lastname: Siciliano
authors.forename: G
authors.initials: G
authors.lastname: Sindona
mesh_terms: D015224:Dideoxynucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D009690:Nucleic Acid Conformation; D010080:Oxazoles / Q000737:chemistry; D016339:Spectrometry, Mass, Fast Atom Bombardment
chemical_list: D015224:Dideoxynucleosides; D010080:Oxazoles