title: Idiopathic bone marrow edema lesions of the femoral head: predictive value of MR imaging findings.
abstract: OBJECTIVE
  To determine the frequency of several subchondral magnetic resonance (MR) imaging features observed in bone marrow edema lesions of the femoral head and to determine their value for differentiation of irreversible from transient lesions.
  
  
  METHODS
  The authors reviewed MR images of 72 femoral head lesions in 42 men and 25 women (median age, 48 years) with equivocal radiographic findings and bone marrow edema seen at MR imaging (T1- and T2-weighted images in all patients and contrast material-enhanced T1-weighted images in 39 patients). Follow-up MR images showed 57 lesions to be transient and 15 to be irreversible. The presence and size of subtle subchondral features observed on initial MR images were compared for both types of lesion.
  
  
  RESULTS
  Lack of any additional subchondral change on T2-weighted or contrast-enhanced T1-weighted images had 100% positive predictive value for transient lesions. For irreversible lesions, presence of a subchondral area of low signal intensity at least 4 mm thick or 12.5 mm long had positive predictive values of 85% and 73%, respectively, on T2-weighted images and 87% and 86%, respectively, on contrast-enhanced T1-weighted images.
  
  
  CONCLUSIONS
  Careful assessment of subchondral changes enables confident differentiation between early irreversible lesions and transient bone marrow edema lesions.
authors.affiliation: Department of Radiology and Medical Imaging, Cliniques Universitaires St Luc, Universite catholique de Louvain, Brussels, Belgium. vandeberg@rdgn.ucl.ac.be
authors.forename: B C
authors.initials: BC
authors.lastname: Vande Berg
authors.forename: J J
authors.initials: JJ
authors.lastname: Malghem
authors.forename: F E
authors.initials: FE
authors.lastname: Lecouvet
authors.forename: J
authors.initials: J
authors.lastname: Jamart
authors.forename: B E
authors.initials: BE
authors.lastname: Maldague
mesh_terms: D001855:Bone Marrow Diseases / Q000473:pathology*; D003937:Diagnosis, Differential; D004487:Edema / Q000473:pathology*; D005260:Female; D005270:Femur Head / Q000473:pathology; D005271:Femur Head Necrosis / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011237:Predictive Value of Tests; D012372:ROC Curve; D012680:Sensitivity and Specificity