Alkaloids from the roots of goniothalamus griffithii
Three new alkaloids-griffithazanone A (1), griffithdione (2), and griffithinam (3)-were isolated from the roots of Goniothalamus griffithii, along with six known compounds, 4-methyl-2,9, 10-(2H)-1-azaanthracenetrione (4), velutinam, aristololactam BI, aristololactam BII, aristololactam AII, and norcepharanone B. Their structures were elucidated on the basis of spectral and chemical methods. The absolute configuration of griffithazanone A (1) was determined by the preparation of Mosher's esters.
Zhang
YJ
Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, People's Republic of China.
Kong
M
Chen
RY
Yu
DQ