Narrow-band collisional activation technique for ion trap mass spectrometers.
Narrow-bandwidth signals were applied to the end caps of an ion trap mass spectrometer to excite ions during collisional activation. Excitation waveforms were created from a single-frequency component and a random noise component using a multiplier circuit. Tandem and higher order mass spectrometry experiments (MS3) can be performed without optimization of the supplemental frequency applied to the end cap electrodes. The usefulness of this method of ion excitation is demonstrated using singly and multiply protonated peptide ions as well as sodium-cationized carbohydrates.
Baker
A G
AG
Department of Chemistry, Indiana University, Bloomington 47405, USA.
Alexander
A
A
Novotny
M V
MV
D000595:Amino Acid Sequence; D000804:Angiotensin II / Q000737:chemistry; D002240:Carbohydrate Sequence; D013058:Mass Spectrometry / Q000379:methods*; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000737:chemistry
D009844:Oligosaccharides; D000804:Angiotensin II; C005695:stachyose