Nortestosterone: endogenous in urine of goats, sheep and mares?
For a number of species it is known that nortestosterone, either the alpha- or beta-epimer, can be of endogenous origin. For goats and mares similar results have not yet been published. As a follow-up on the experiments with cattle, a large number of urine samples per animal were collected from pregnant goats, sheep and mares. These samples were analysed for the presence of alpha- and beta-nortestosterone and alpha-estradiol using GC-MS. The results show that in the goats and mares studied alpha-nortestosterone is present during pregnancy. In this study no alpha-nortestosterone could be demonstrated in sheep. From our study and recently published data, however, it is proven that alpha-nortestosterone can occur endogenously.
Sterk
S
S
National Institute of Public Health and the Environment (RIVM), European Union Community Reference Laboratory, Bilthoven, The Netherlands.
Herbold
H
H
Blokland
M
M
van Rossum
H
H
van Ginkel
L
L
Stephany
R
R
D045930:Anabolic Agents / Q000737:chemistry / Q000652:urine*; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006041:Goats / Q000652:urine; D006736:Horses / Q000652:urine*; D007536:Isomerism; D009277:Nandrolone / Q000737:chemistry / Q000652:urine*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000652:urine*; D012418:Ruminants / Q000652:urine*; D012756:Sheep / Q000652:urine; D013739:Testosterone / Q000737:chemistry / Q000652:urine
D045930:Anabolic Agents; D013739:Testosterone; D009277:Nandrolone