[Disorders of equilibrium between pro- and antioxidant metalloprotein action in blood of albino rats after gangliosympathectomy and its combination with acute acoustic stress].
Unilateral ganglionsympathetectomy-removal of right upper cervical sympathetic ganglia and its combination with acute acoustic stress results in intensification of process of free radical oxidation of lipids and balance disturbance between components of antioxidative and pro-oxidative system of blood. Changes of composition and activity Cu, Zn-superoxide dismutase, catalase activity and contents of catalase, ceruloplasmin, transferrin and metalloproteins pro-oxidative action such as (cytochromes b558(I), b558(II), b558(III), b558(IV)) as well as O2-producing lipoprotein suprol and cytochromes b5 are evidence of compensating-adoptive function disturbances with according changes in blood, relatively to adaptive-trophic function of sympathetic system, its regulative role, in system of tissue metabolic conversion, which is directed, in particular, on compensation of anti-radical protection of cells.
Martirosian
A G
AG
Institute of Molecular Biology of Armenian NAS, Erevan State Medical University, Institute of Biochemistry of NASPA.
Karagezian
K G
KG
Obeian
G A
GA
Melkonian
M M
MM
Simonian
M A
MA
Badalian
M A
MA
Karagezian
M K
MK
D000161:Acoustic Stimulation; D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D002570:Ceruloplasmin / Q000378:metabolism; D003573:Cytochrome b Group / Q000378:metabolism; D015171:Ganglionectomy; D006706:Homeostasis; D008297:Male; D008667:Metalloproteins / Q000378:metabolism*; D016877:Oxidants / Q000378:metabolism*; D051381:Rats; D013312:Stress, Physiological / Q000378:metabolism*; D017783:Superior Cervical Ganglion / Q000502:physiology; D013482:Superoxide Dismutase / Q000378:metabolism; D013562:Sympathectomy; D014168:Transferrin / Q000378:metabolism
D000975:Antioxidants; D003573:Cytochrome b Group; D008667:Metalloproteins; D016877:Oxidants; D014168:Transferrin; D002374:Catalase; D013482:Superoxide Dismutase; D002570:Ceruloplasmin
Narusheniia ravnovesiia mezhdu metalloproteinami pro- i antioksidantnogo deĭstviia v krovi belykh krys pri gangliosimpatéktomii i ee sochetanii s ostrymakusticheskim stressom.