title: Pneumomediastinum complicating bleomycin related lung damage.
abstract: We describe two patients who developed spontaneous pneumomediastinum without pneumothorax against a background of bleomycin-induced pulmonary interstitial disease whilst on treatment for metastatic germ cell tumours of the testis. Pneumomediastinum is a rare but recognized complication of bleomycin-induced lung toxicity, which has previously only been described in association with pneumothorax.
authors.affiliation: Department of Radiology, Royal Marsden NHS Trust, Sutton, Surrey, UK.
authors.forename: T
authors.initials: T
authors.lastname: Sikdar
authors.forename: D
authors.initials: D
authors.lastname: MacVicar
authors.forename: J E
authors.initials: JE
authors.lastname: Husband
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D001761:Bleomycin / Q000009:adverse effects*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced*; D008297:Male; D008478:Mediastinal Emphysema / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008875:Middle Aged; D011859:Radiography
chemical_list: D000964:Antimetabolites, Antineoplastic; D001761:Bleomycin