title: Primary squamous cell carcinoma of the thyroid diagnosed by fine needle aspiration cytology. A report of two cases.
abstract: BACKGROUND
  Primary squamous cell carcinoma of the thyroid is a rare malignant tumor that needs to be distinguished from other neoplasms.
  
  
  METHODS
  Two males aged 65 and 68 years presented with an enlarged right lobe of the thyroid. Thyroid scintigraphy revealed a cold nodule. Clinically malignancy was suspected. Fine needle aspiration (FNA) revealed numerous clusters and isolated malignant cells, dyskeratotic cells and deposits of eosinophilic granular keratin material. Subtotal thyroidectomy was performed. Histologic findings confirmed the cytologic diagnosis of squamous cell carcinoma.
  
  
  CONCLUSIONS
  Primary squamous cell carcinoma of the thyroid is a rare tumor. FNA findings of this tumor were not reported before. FNA study cannot help to differentiate primary from metastatic squamous cell carcinoma of the thyroid.
authors.affiliation: Department of Pathology, Shiraz Medical School, Shiraz University of Medical Sciences, Iran.
authors.forename: P V
authors.initials: PV
authors.lastname: Kumar
authors.forename: S A
authors.initials: SA
authors.lastname: Malekhusseini
authors.forename: A R
authors.initials: AR
authors.lastname: Talei
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D006652:Histological Techniques; D006801:Humans; D008297:Male; D013964:Thyroid Neoplasms / Q000473:pathology*