Stereoselective syntheses of phosphorylated and sulfated glycosyl serines in glycosaminoglycan for biological probes.
Phosphorylated glycosyl serines of glycosaminoglycan with/without sulfate: beta-D-Xyl(2P)-Ser (1) and beta-D-Gal(+/-6S)-(1->4)-beta-D-Xyl(2P)-Ser (2, 3) were suitably designed for biological probes. These oligosaccharides were synthesized in a stereocontrolled manner.
Tamura
J
J
Department of Environmental Sciences, Faculty of Education & Regional Sciences, Tottori University, Japan.
Nishihara
J
J
D004187:Disaccharides / Q000138:chemical synthesis* / Q000378:metabolism*; D006001:Glycoconjugates / Q000138:chemical synthesis* / Q000378:metabolism*; D006025:Glycosaminoglycans / Q000737:chemistry* / Q000378:metabolism; D015335:Molecular Probes / Q000138:chemical synthesis* / Q000378:metabolism*; D009005:Monosaccharides / Q000138:chemical synthesis* / Q000378:metabolism*; D010766:Phosphorylation; D012694:Serine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D013237:Stereoisomerism; D013431:Sulfates / Q000737:chemistry
D004187:Disaccharides; D006001:Glycoconjugates; D006025:Glycosaminoglycans; D015335:Molecular Probes; D009005:Monosaccharides; D013431:Sulfates; C121284:xylose-Serine; D012694:Serine; C066060:O-beta-galactopyranosyl-(1-4)-O-beta-xylopyranosyl-(1-0)-serine