[Bullous phototoxic contact dermatitis caused by Ruta graveolens L. (garden rue), Rutaceae. Case report and review of literature].
A patient developed severe bullous phototoxic contact dermatitis caused by Ruta graveolens L. (garden rue) which belongs to the Rutaceae family. To date only a few cases of phototoxic reactions to the garden rue have been reported. The phototoxic components of Ruta graveolens L. are the fouranocoumarins 5-methoxypsoralen (bergapten) and 8-methoxypsoralen (xanthotoxine), and the furanoquinoline dictamnine whose phototoxic properties were recently discovered. Since the garden rue is frequently cultivated, it should be considered in the differential diagnosis of phototoxic phytodermatitis.
Schempp
C M
CM
Universitäts-Hautklinik, Klinikum der Albert-Ludwigs-Universität Freiburg.
Schöpf
E
E
Simon
J C
JC
D000078223:5-Methoxypsoralen; D000470:Alkaloids / Q000009:adverse effects; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D002273:Carcinogens / Q000009:adverse effects; D003432:Cross-Linking Reagents / Q000009:adverse effects; D017484:Dermatitis, Phototoxic / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D003937:Diagnosis, Differential; D006801:Humans; D019684:Magnoliopsida; D008297:Male; D008730:Methoxsalen / Q000009:adverse effects / Q000031:analogs & derivatives; D008875:Middle Aged; D010636:Phenols / Q000627:therapeutic use; D017319:Photosensitizing Agents / Q000009:adverse effects; D011804:Quinolines; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced / Q000175:diagnosis* / Q000188:drug therapy; D017967:Zinc Compounds / Q000627:therapeutic use
D000470:Alkaloids; D000891:Anti-Infective Agents, Local; D002273:Carcinogens; D003432:Cross-Linking Reagents; D010636:Phenols; D017319:Photosensitizing Agents; D011804:Quinolines; D017967:Zinc Compounds; D000078223:5-Methoxypsoralen; C026398:dictamnine; D008730:Methoxsalen; C004554:2,4,6-tribromophenol
Dermatitis bullosa striata pratensis durch Ruta graveolens L. (Gartenraute).