[The role of hereditary factors in the development of thyroid nodular formations].
As many as 479 patients with focal pathology of the thyroid gland were exposed to a surgical or conservative treatment over the period of 1991-1997. Based on the clinical and genealogical investigation in 78 subjects of the above series it was ascertained that heredity has a part in the origination of euthyroid and toxic adenomas, multinodular toxic goiter, and recurring non-toxic nodular goiter (37.3%, 29.6%, and 64.2% respectively). Heredity-related forms of thyroid nodular formations are characterized by progressive irreversible development of the abnormality, low efficiency of suppressive therapy, which fact warrants a surgical treatment to be initiated together with an attentive prophylaxis of development of relapses.
Cheren'ko
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D000236:Adenoma / Q000209:etiology / Q000235:genetics; D000328:Adult; D006044:Goiter, Nodular / Q000209:etiology / Q000235:genetics; D006801:Humans; D008875:Middle Aged; D010375:Pedigree; D013964:Thyroid Neoplasms / Q000209:etiology / Q000235:genetics; D016606:Thyroid Nodule / Q000209:etiology / Q000235:genetics* / Q000628:therapy
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