title: Massive T wave changes following a combined kidney and liver transplant in a young female with cirrhosis.
abstract: We report the case of a young female with PSC-associated cirrhosis and chronic renal failure who developed clinical and electrocardiographic signs consistent with acute myocardial infarction after a combined kidney and liver transplant. Cardiac investigations at that time were negative and she is currently asymptomatic one year post-transplant with resolution of most of her ECG abnormalities. Although the cause of her symptoms and ECG abnormalities is not immediately apparent, this case illustrates the difficulties in interpreting abnormal cardiac investigations in transplanted patients with liver cirrhosis who may have a background of subclinical cardiac disease.
authors.affiliation: Scottish Liver Transplant Unit, Royal Infirmary of Edinburgh, UK. gthera@srv2.med.ed.ac.uk
authors.forename: G
authors.initials: G
authors.lastname: Therapondos
authors.forename: J N
authors.initials: JN
authors.lastname: Plevris
authors.forename: P F
authors.initials: PF
authors.lastname: Currie
authors.forename: P C
authors.initials: PC
authors.lastname: Hayes
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use; D015209:Cholangitis, Sclerosing / Q000601:surgery*; D003424:Crohn Disease / Q000188:drug therapy; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016030:Kidney Transplantation; D016031:Liver Transplantation; D019804:Mesalamine / Q000009:adverse effects / Q000627:therapeutic use; D009203:Myocardial Infarction / Q000175:diagnosis*; D009395:Nephritis, Interstitial / Q000139:chemically induced / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D019804:Mesalamine