Recurrent Wilms' tumour or retroperitoneal teratoma? A challenging case.
The clinical and pathological features of a left renal tumour and a subsequent retroperitoneal tumour in a 2-year-old boy are presented. The nephrectomy specimen showed typical features of a triphasic Wilms' tumour with focal heterologous elements and intralobar nephrogenic rests. The tumour was assessed as clinical stage III and post-operative chemotherapy and radiotherapy were administered. A retroperitoneal mass, detected following completion of postoperative therapy, was mainly made up of skeletal muscle and mature adipose tissue. Nests of epithelium resembling ameloblastic nests and a unique structure reminiscent of a developing tooth were present.
Govender
D
D
Department of Pathology, University of Natal Medical School and King Edward VIII Hospital, Durban, South Africa. govendh@med.und.ac.za
Hadley
G P
GP
D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D016609:Neoplasms, Second Primary; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D013724:Teratoma / Q000175:diagnosis* / Q000473:pathology; D009396:Wilms Tumor / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*