title: Hepatocellular carcinoma in a patient with hereditary hemochromatosis and noncirrhotic liver. A case report.
abstract: A case of a 62-year-old patient with hereditary hemochromatosis is reported, who developed hepatocellular carcinoma (HCC) in the absence of cirrhosis and other potential risk factors for HCC. Occurrence of HCC in patients with genetic hemochromatosis and noncirrhotic liver is a rare event which has previously been described only six times and appears to be limited to male patients.
authors.affiliation: Institute of Pathology, Johannes-Gutenberg-University, Mainz, Germany.
authors.forename: H H
authors.initials: HH
authors.lastname: Köhler
authors.forename: T
authors.initials: T
authors.lastname: Höhler
authors.forename: U
authors.initials: U
authors.lastname: Küsel
authors.forename: C J
authors.initials: CJ
authors.lastname: Kirkpatrick
authors.forename: P
authors.initials: P
authors.lastname: Schirmacher
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000150:complications* / Q000378:metabolism / Q000473:pathology*; D006680:HLA Antigens / Q000235:genetics / Q000378:metabolism; D006432:Hemochromatosis / Q000150:complications* / Q000235:genetics; D000071020:Hemochromatosis Protein; D006485:Hemosiderin / Q000378:metabolism; D015395:Histocompatibility Antigens Class I / Q000235:genetics / Q000378:metabolism; D006801:Humans; D007501:Iron / Q000378:metabolism; D008113:Liver Neoplasms / Q000150:complications* / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008565:Membrane Proteins; D008875:Middle Aged
chemical_list: C103673:HFE protein, human; D006680:HLA Antigens; D000071020:Hemochromatosis Protein; D015395:Histocompatibility Antigens Class I; D008565:Membrane Proteins; D006485:Hemosiderin; D007501:Iron