title: [Homocysteine--a routine biochemical parameter in cardiovascular diseases?].
abstract: An elevated level of total homocysteine (tHcy) in blood-hyperhomocysteinemia, is prevalent and strong risk factor for atherosclerotic vascular disease in the coronary, cerebral and peripheral vessels and for thromboembolism (arterial and venous). Elevated total homocysteine confers a graded risk with no threshold, is independent of but may enhance the effect of conventional risk factors. Hyperhomocysteinemia seems to be a particularly strong predictor of cardiovaskular mortality. Supplementation with B-vitamins, in particular with folic acid, is an efficient, safe and inexpensive means to reduce an elevated total homocysteine level.
authors.affiliation: Oddelenie klinickej biochémie NsP F. D. Roosevelta, Banská Bystrica.
authors.forename: D
authors.initials: D
authors.lastname: Gábor
authors.forename: J
authors.initials: J
authors.lastname: Hrnciar
authors.forename: I
authors.initials: I
authors.lastname: Hricová
authors.forename: M
authors.initials: M
authors.lastname: Zacharová
mesh_terms: D001161:Arteriosclerosis / Q000097:blood; D002318:Cardiovascular Diseases / Q000097:blood* / Q000401:mortality; D006710:Homocysteine / Q000097:blood* / Q000378:metabolism; D006801:Humans; D012307:Risk Factors
chemical_list: D006710:Homocysteine
vernacular_title: Homocysteín--rutinný biochemický parameter pri kardiovaskulárnych ochoreniach?