title: [Evaluation technics of the anticaries potential of fluoride-releasing materials].
abstract: Clinical evaluation of anticariogenic potential of fluoride releasing materials seems to be the best way to evaluate products effectiveness. This is an expensive, lengthy and difficult process to realise. Yet there is a need to determine the relative effectiveness of different materials so that clinicians can make rational decision on what materials to use. Fluoride release measurement and fluoride uptake in dental tissues, antibacterial effect evaluation and caries-like lesion inhibition constitute a part of different model investigations use to study fluoride releasing materials. Even if the results of these different in vitro model systems may not be directly transposed to clinical reality, they give some useful information to determine anticariogenic potential of some dental materials. Three materials are analyzed: glass ionomer cements (conventional and resin-modified), polyacid modified resin composites and fluorated resin composites. Results obtained are different for the three kind of materials. Glass ionomer cements show much more anticariogenic properties than polyacid modified resin composites and fluorated resin composites. These two last products are more difficult to distinguish. It is probably due to their similar chemical properties. Even if these products don't have a large anticariogenic effect, it could be enough to prevent secondary caries. The anticariogenic action is principally due to the fluoride release of the materials. That's why it is necessary to define the acceptable level of fluoride release, which is required to have anticariogenic action.
authors.affiliation: Service de Pathologie et Thérapeutique Dentaires, Ecole de Médecine Dentaire et de Stomatologie, Université Catholique de Louvain, Bruxelles.
authors.forename: G
authors.initials: G
authors.lastname: Vermeersch
authors.forename: G
authors.initials: G
authors.lastname: Leloup
authors.forename: J
authors.initials: J
authors.lastname: Vreven
mesh_terms: D001419:Bacteria / Q000187:drug effects; D001672:Biocompatible Materials / Q000737:chemistry*; D002327:Cariostatic Agents / Q000008:administration & dosage* / Q000737:chemistry / Q000493:pharmacokinetics; D003188:Composite Resins / Q000737:chemistry; D003731:Dental Caries / Q000517:prevention & control; D003743:Dental Enamel / Q000378:metabolism; D003764:Dental Materials / Q000737:chemistry*; D003804:Dentin / Q000378:metabolism; D005069:Evaluation Studies as Topic; D005459:Fluorides / Q000008:administration & dosage* / Q000737:chemistry / Q000493:pharmacokinetics; D005899:Glass Ionomer Cements / Q000737:chemistry; D006801:Humans; D019279:Resin Cements / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D002327:Cariostatic Agents; D003188:Composite Resins; D003764:Dental Materials; D005899:Glass Ionomer Cements; D019279:Resin Cements; D005459:Fluorides
vernacular_title: Techniques d'évaluation du potentiel anticarie des matériaux libérateurs de fluorures.