title: [Cu2+-induced permeability of the Escherichia coli cytoplasmic membrane].
abstract: Cu(2+)-induced permeability of cytoplasmic membranes of Escherichia coli for different cations and neutral molecules of saccharose was estimated by studying their effect on cell plasmolysis during uncharged exchange of cytoplasmic K+ ions by periplasmic space cations. The addition of copper resulted in the exchange of K+ ions by periplasmic Na+, Tris+, streptomycin2+, Cu2+, Ca2+, Mg2+, Cd2+, and Mn2+. It is concluded that Cu(2+)-induced conducting pathways in bacterial membranes are hydrophilic channels with a radius of approximately 0.5 nm and a nonselective permeability for different cations.
authors.affiliation: Institute of Energy Problems of Chemical Physics, Russian Academy of Sciences, Moscow, Russia.
authors.forename: V S
authors.initials: VS
authors.lastname: Lebedev
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Deĭnega
authors.forename: T A
authors.initials: TA
authors.lastname: Kuzovnikova
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Fedorov
mesh_terms: D002462:Cell Membrane / Q000378:metabolism; D002463:Cell Membrane Permeability / Q000187:drug effects*; D003300:Copper / Q000494:pharmacology*; D003593:Cytoplasm / Q000378:metabolism*; D004926:Escherichia coli / Q000187:drug effects* / Q000378:metabolism; D017136:Ion Transport
chemical_list: D003300:Copper
vernacular_title: Cu2+-indutsirovannaia pronitsaemost' tsitoplazmaticheskoĭ membrany Escherichia coli.