[A clinical study of early enteral feeding to protect the gut function in burned patients].
In order to investigate the effects of early enteral feeding on the gut after burn, 21 cases (mean burn area 45%) were randomly divided into early feeding group (EF group) and delayed feeding group (DF group). The results showed that the levels of plasma endotoxin and MDA in EF group were much lower on PBD 4, 8, 14 than those of DF group (P < 0.05-0.01), and plasma SOD was much lower in DF group on PBD 4, 8 (P < 0.01). The contents of serum gastrin and plasma motilin were obviously increased, and TNF IL-8 much lower in EF group at most time points (P < 0.05-0.01). Therefore, it seems that the early enteral feeding can decrease the level of plasma endotoxin in blood, reduce reperfusion injury of the gut, and blunt the chain reaction of "endotoxin-inflammatory mediator-gut mucosa injury."
Wang
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S
Department of Surgery, 47th Army Hospital of People's Liberation Army, Chengdu.
Wang
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S
Li
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A
D000293:Adolescent; D000328:Adult; D002056:Burns / Q000503:physiopathology / Q000628:therapy*; D004064:Digestive System / Q000503:physiopathology*; D004731:Endotoxins / Q000097:blood; D004750:Enteral Nutrition; D005260:Female; D006801:Humans; D007441:Intubation, Gastrointestinal; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D004731:Endotoxins