[Cu2+-induced permeability of the Escherichia coli cytoplasmic membrane].
Cu(2+)-induced permeability of cytoplasmic membranes of Escherichia coli for different cations and neutral molecules of saccharose was estimated by studying their effect on cell plasmolysis during uncharged exchange of cytoplasmic K+ ions by periplasmic space cations. The addition of copper resulted in the exchange of K+ ions by periplasmic Na+, Tris+, streptomycin2+, Cu2+, Ca2+, Mg2+, Cd2+, and Mn2+. It is concluded that Cu(2+)-induced conducting pathways in bacterial membranes are hydrophilic channels with a radius of approximately 0.5 nm and a nonselective permeability for different cations.
Lebedev
V S
VS
Institute of Energy Problems of Chemical Physics, Russian Academy of Sciences, Moscow, Russia.
Deĭnega
E Iu
EIu
Kuzovnikova
T A
TA
Fedorov
Iu I
IuI
D002462:Cell Membrane / Q000378:metabolism; D002463:Cell Membrane Permeability / Q000187:drug effects*; D003300:Copper / Q000494:pharmacology*; D003593:Cytoplasm / Q000378:metabolism*; D004926:Escherichia coli / Q000187:drug effects* / Q000378:metabolism; D017136:Ion Transport
D003300:Copper
Cu2+-indutsirovannaia pronitsaemost' tsitoplazmaticheskoĭ membrany Escherichia coli.