title: Bisalbuminuria in an adult with bisalbuminemia and nephrotic syndrome.
abstract: Bisalbuminemia (or alloalbuminemia) is a relatively rare hereditary or acquired condition characterized by the presence of two distinct albumin bands, or, less commonly, a single widened albumin band, after agarose gel electrophoresis of serum. Bisalbumins are caused by point- or chain-mutations that occur with a population frequency of 1:10,000 to 1:1000. Although no adverse clinical effects have been attributed to bisalbumins, some albumin variants have altered affinity for steroid hormones, thyroxine, or drugs. We report a case of bisalbuminuria in a 25-year-old man with bisalbuminemia and nephrotic syndrome.
authors.affiliation: Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235-9073, USA.
authors.forename: M P
authors.initials: MP
authors.lastname: Hoang
authors.forename: L B
authors.initials: LB
authors.lastname: Baskin
authors.forename: F H
authors.initials: FH
authors.lastname: Wians
mesh_terms: D000328:Adult; D000418:Albumins / Q000032:analysis*; D000419:Albuminuria / Q000150:complications*; D004587:Electrophoresis, Agar Gel; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications*; D012709:Serum Albumin / Q000032:analysis*
chemical_list: D000418:Albumins; D012709:Serum Albumin; C030764:bisalbumins