Evidence for cyclophosphate formation during hydrolysis of 3-methyl-cycloSal-PCVMP.
A hydrolysis study of 3-methyl-cycloSal-PCVMP 2 is described. Surprisingly, phosphotriester 5 released in this study not the expected PCVMP, but cycloPCVMP.
Lomp
A
A
Institut für Organische Chemie, Universität Hamburg, Germany.
Meier
C
C
Herderich
M
M
Wutzler
P
P
D000212:Acyclovir / Q000031:analogs & derivatives* / Q000737:chemistry; D006207:Half-Life; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009943:Organophosphorus Compounds / Q000138:chemical synthesis*
C120721:3-methyl-cyclosal-PCVMP; D009943:Organophosphorus Compounds; D000212:Acyclovir