A saponin with anti-ulcerogenic effect from the flowers of Spartium junceum.
A new oleanene-type saponin with potent anti-ulcerogenic activity was isolated from the flowers of Spartium junceum. The various techniques of NMR spectral analysis, viz. 1H, 13C, DEPT, C-H COSY, H-H COSY, COLOC, NOESY, HMBC, HMQC, in conjunction with EI- and FAB-mass spectrometry, revealed that the structure of the isolated saponin was 3-O-[alpha-L-rhamnopyranosyl-(1-->2) -O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucuronopyranosyl]-3 beta,16beta,22 beta,24-tetrahydroxy-olean-12-ene and named as spartitrioside.
Yeşilada
E
E
Gazi University, Faculty of Pharmacy, Ankara, Turkey. yesilada@tr-net.net.tr
Takaishi
Y
Y
D000818:Animals; D000897:Anti-Ulcer Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002240:Carbohydrate Sequence; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D009828:Oleanolic Acid / Q000031:analogs & derivatives*; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000897:Anti-Ulcer Agents; D012503:Saponins; C121080:spartitrioside; D009828:Oleanolic Acid