title: Gastric carcinoma in Sotos syndrome (cerebral gigantism).
abstract: We report the first case of the association of Sotos syndrome and gastric carcinoma (containing signet ring cells) in a twin patient. The other-probably monozygous-twin is also affected by the Sotos syndrome. The association of malign tumors in Sotos syndrome and other overgrowth syndromes is discussed.
authors.affiliation: Service de Génétique Médicale, CHRU, Hôpital Pontchaillou, Rennes, France.
authors.forename: B
authors.initials: B
authors.lastname: Le Marec
authors.forename: L
authors.initials: L
authors.lastname: Pasquier
authors.forename: C
authors.initials: C
authors.lastname: Dugast
authors.forename: M
authors.initials: M
authors.lastname: Gosselin
authors.forename: S
authors.initials: S
authors.lastname: Odent
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000235:genetics*; D018279:Carcinoma, Signet Ring Cell / Q000235:genetics*; D005877:Gigantism / Q000235:genetics*; D006801:Humans; D013274:Stomach Neoplasms / Q000235:genetics*; D014430:Twins, Monozygotic