title: Partial fundoplications for gastroesophageal reflux disease: indications and current status.
abstract: The Nissen fundoplication, and in particular the laparoscopic Nissen fundoplication, has received widespread acceptance as the most definitive therapy for gastroesophageal reflux disease. There remains, however, certain patients who do better with a less aggressive surgical augmentation of the lower esophageal sphincter. Partial fundoplications originated in the early 1960s as an alternative procedure to the Nissen, which was associated with moderately high rates of postoperative side effects. These "more physiologic" procedures have proved successful in the treatment of reflux disease in patients with poor or no esophageal motility. In particular, the use of partial fundoplications in association with Heller's myotomy for achalasia has been demonstrated to be well tolerated and to reduce the risk of late dysphasia resulting from uncontrolled gastroesophageal reflux (GER). The use of partial fundoplications in GER patients with normal motility, however, has been less successful. High recurrence rates are documented by many centers with the main cause appearing to be related to a less competent neo-lower esophageal sphincter and a higher rate of wrap herniation. This has led to the current practice of a "tailored approach" to reflux disease, in which all patients receive a thorough preoperative physiologic evaluation to determine the best antireflux procedure for the individual. This is generally a Nissen repair for those with normal motility and either an extrashort "floppy" Nissen or a partial wrap for those with impaired peristalsis.
authors.affiliation: Department of Surgery, Oregon Health Sciences University, Portland, USA.
authors.forename: L L
authors.initials: LL
authors.lastname: Swanstrom
mesh_terms: D004724:Endoscopy; D004931:Esophageal Achalasia / Q000601:surgery; D015154:Esophageal Motility Disorders / Q000601:surgery; D004943:Esophagogastric Junction / Q000503:physiopathology / Q000601:surgery; D018662:Fundoplication / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D005769:Gastrointestinal Motility; D006801:Humans; D016896:Treatment Outcome