title: The digital pathologies of chronic laminitis.
abstract: This review indicates that the patient-to-patient uniqueness commonly seen in chronic laminitis represents the variable presence of the digital pathologies. Although some degree of mechanical failure is always present, the secondary metabolic and growth dysplasias, vascular pathologies, and sepsis may or may not be evident. The presence and severity of these pathologies appear to have a more significant impact on the prognosis of individual cases than does the displacement of the distal phalanx. It should be reiterated that it is often the combined presence of these individual pathologies that gives rise to the patient that is totally refractory to treatment. In the absence of these pathologies, many horses with significant displacement of the distal phalanx are not in pain and are not in need of treatment. It thus follows that a key to the improved rehabilitation of difficult patients is focusing research on the physiopathology and diagnosis of these nonmechanical problems.
authors.affiliation: Department of Animal Health Research and Development, Abbott Laboratories, North Chicago, Illinois, USA.
authors.forename: D A
authors.initials: DA
authors.lastname: Grosenbaugh
authors.forename: S J
authors.initials: SJ
authors.lastname: Morgan
authors.forename: D M
authors.initials: DM
authors.lastname: Hood
mesh_terms: D000818:Animals; D002908:Chronic Disease; D005534:Foot Diseases / Q000473:pathology / Q000662:veterinary*; D006724:Hoof and Claw / Q000254:growth & development / Q000378:metabolism / Q000473:pathology*; D006734:Horse Diseases / Q000473:pathology*; D006736:Horses; D007249:Inflammation / Q000473:pathology / Q000662:veterinary; D007633:Keratins / Q000378:metabolism
chemical_list: D007633:Keratins