title: [Oral dormicum premedication of children in day surgery].
abstract: Thirty-four patients aged 5-14 years were observed, divided into age groups OF 5-8 and 8-14 years. Cardiovascular function was evaluated by central hemodynamic parameters and cardiointervalography. Changes in external respiration parameters were studied. The efficacy of premedication was assessed by objective parameters and by clinical signs. Each patient was examined 4 times at the following stages: 1) before premedication; 2) at the 10th min; 3) at the 20th min; and 4) at the 30th min. Oral premedication with dormicum in a dose of 0.5 mg/kg did not affect heart rate or arterial pressure. By the 20th min it notably decreased total peripheral resistance, significantly decreased the respiratory volume, increased respiration rate, and decreased sympathetic tone in younger children. In older children the premedication virtually did not affect total peripheral resistance and facilitated heart work, increased the respiratory volume, rarefied the respiratory rate, and did not affect the autonomic regulation balance. Younger children fell asleep without excitation or negativism; 35.2% developed psychomotor reactions. In older group the effect was good in 71.1% children, the rest had "apparitions" starting from the 17th min: doubling of the staff's faces, white spiders, or white moths.
authors.forename: I F
authors.initials: IF
authors.lastname: Ostreĭkov
authors.forename: S A
authors.initials: SA
authors.lastname: Pivovarov
authors.forename: V V
authors.initials: VV
authors.lastname: Milenin
authors.forename: M V
authors.initials: MV
authors.lastname: Shishkova
authors.forename: Ia I
authors.initials: IaI
authors.lastname: Vasil'ev
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000367:Age Factors; D000556:Ambulatory Surgical Procedures; D014151:Anti-Anxiety Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D008874:Midazolam / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D011229:Preanesthetic Medication; D012119:Respiration / Q000187:drug effects
chemical_list: D014151:Anti-Anxiety Agents; D006993:Hypnotics and Sedatives; D008874:Midazolam