Discordance of primary infantile glaucoma in monozygotic twins.
OBJECTIVE
To report a case of primary infantile glaucoma occurring in only one of two identical twins.


METHODS
Case reports.


RESULTS
Clinical features of bilateral primary infantile glaucoma in one of the two twins at age 16 months are described. Polymorphic DNA markers were used to establish identical twinship.


CONCLUSIONS
Our finding suggests that nongenetic factors must be considered in determining the origin of primary infantile glaucoma.
Zhang
K
K
Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.
Jampel
H D
HD
D002889:Chromosomes, Human, Pair 2 / Q000235:genetics; D004247:DNA / Q000032:analysis; D004200:Diseases in Twins / Q000235:genetics*; D005260:Female; D005819:Genetic Markers; D005838:Genotype; D005901:Glaucoma / Q000235:genetics*; D006801:Humans; D007223:Infant; D007429:Intraocular Pressure; D014430:Twins, Monozygotic / Q000235:genetics*
D005819:Genetic Markers; D004247:DNA