title: [Serum sickness in diphtheria].
abstract: As many as 2247 patients with different clinical forms of diphtheria were examined. Antidiphtheric serum (ADS) was administered in 1556 children, the dosage being determined by condition of the patient. Serum sickness developed at day 7 to 9 in 24 (1.5%); 10 patients were found to run a mild course, 14--moderately severe. 6 patients had allergic reactions: 3--to antibiotic (penicillin), urticaria type, 1--to pertussoid-tetanic anatoxin, 2 had pollinosis-type reaction. Thus, serum sickness has practical value, which fact requires a detailed allergic history together with skin tests to be performed before the administration of ADS.
authors.forename: Zh I
authors.initials: ZhI
authors.lastname: Vozianova
authors.forename: K I
authors.initials: KI
authors.lastname: Chepilko
mesh_terms: D000208:Acute Disease; D004165:Diphtheria / Q000150:complications* / Q000628:therapy; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000009:adverse effects; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D010406:Penicillins / Q000009:adverse effects; D012713:Serum Sickness / Q000175:diagnosis / Q000209:etiology*; D013997:Time Factors
chemical_list: D015721:Diphtheria-Tetanus-Pertussis Vaccine; D010406:Penicillins