[Prognosis of postinjection abscesses course with use of mathematical model].
Virulent and persistent characteristics of staphylococci isolated from 100 patients with various types of course of the abscessed forms of postinjection suppuration were defined. Comparative analysis of 11 biological characteristics of the microorganisms was carried out. An important role of the complex of properties of Staphylococcus aureus was established, including lysozyme, proteolytic, fibrinolytic activities, ability for inactivation of immunoglobulins through their Fc-receptors' binding to protein A, antilysozyme, "antiinterferon", anticomplement activities in determination of protracted character of festering and inframmatory process initiated by them. The model for prognosis of the course of postinjection abscesses was developed with the help of discriminant analysis, being based on the analysis of the informative properties of the pathogen.
Kurlaev
P P
PP
Bukharin
O V
OV
Chernova
O L
OL
Matiushina
S B
SB
D000038:Abscess / Q000175:diagnosis* / Q000209:etiology / Q000382:microbiology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections / Q000009:adverse effects; D008875:Middle Aged; D008962:Models, Theoretical; D009135:Muscular Diseases / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology; D011379:Prognosis; D012871:Skin Diseases / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000209:etiology / Q000382:microbiology; D013211:Staphylococcus aureus / Q000302:isolation & purification / Q000472:pathogenicity*