title: [Acatalasemia--Takahara's disease].
abstract: The case of a 30 year old man with acatalasemia is presented. The congenital disorder is charaterized by a lack or major reduction of catalase, an enzyme that catalyzes the decomposition of hydrogen peroxide to oxygen and water. The defect is inherited in an autosomal recessive fashion. Occasionally the defect manifests as progressive oral gangrene or Takahara's, disease.
authors.affiliation: Dermatologische Abteilung der Landeskrankenanstallen Saltzburg.
authors.forename: H
authors.initials: H
authors.lastname: Perner
authors.forename: C
authors.initials: C
authors.lastname: Krenkel
authors.forename: B
authors.initials: B
authors.lastname: Lackner
authors.forename: H
authors.initials: H
authors.lastname: Hintner
authors.forename: T
authors.initials: T
authors.lastname: Hawranek
mesh_terms: D020642:Acatalasia / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D000328:Adult; D001706:Biopsy; D002374:Catalase / Q000097:blood; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology
chemical_list: D006861:Hydrogen Peroxide; D002374:Catalase