title: Assessment of body composition using dual energy x-ray absorptiometry in patients with liver cirrhosis: comparison with anthropometry.
abstract: OBJECTIVE
  The aim of this study was to evaluate changes of body composition in cirrhotic patients. Dual energy x-ray absorptiometry (DEXA) and anthropometry were used, and the values obtained were compared.
  
  
  METHODS
  Mid-arm fat and muscle areas were calculated by anthropometry in 66 cirrhotic patients and 94 healthy controls. In 37 of the cirrhotic patients and 39 of the controls, fat mass, lean soft tissue mass and bone mineral contents were measured with DEXA.
  
  
  RESULTS
  The number of cirrhotic patients with measured values below the fifth percentile of normal controls was 21 (31.8%) by mid-arm fat area, six (9.1%) by mid-arm muscle area, 15 (40.5%) by fat mass and 0 (0%) by lean soft tissue mass. The fat mass in cirrhotic patients was less than in controls, whereas lean soft tissue mass and bone mineral content were not different. Fat depletion was severe in Child-class C patients and with severe ascites. Mid-arm fat area and fat mass showed close correlation (r = 0.85, p < 0.01), but mid-arm muscle area and lean soft tissue mass showed poor correlation (r = 0.32, p < 0.05).
  
  
  CONCLUSIONS
  Cirrhotic patients showed lower fat component, with preserved lean soft tissue mass and bone mineral content. In clinical practice, the measurement of mid-arm fat area was useful for the assessment of fat mass.
authors.affiliation: Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea.
authors.forename: S H
authors.initials: SH
authors.lastname: Jeong
authors.forename: J A
authors.initials: JA
authors.lastname: Lee
authors.forename: J A
authors.initials: JA
authors.lastname: Kim
authors.forename: M W
authors.initials: MW
authors.lastname: Lee
authors.forename: H B
authors.initials: HB
authors.lastname: Chae
authors.forename: W J
authors.initials: WJ
authors.lastname: Choi
authors.forename: H S
authors.initials: HS
authors.lastname: Shin
authors.forename: K H
authors.initials: KH
authors.lastname: Lee
authors.forename: S J
authors.initials: SJ
authors.lastname: Youn
authors.forename: S S
authors.initials: SS
authors.lastname: Koong
authors.forename: S M
authors.initials: SM
authors.lastname: Park
mesh_terms: D015502:Absorptiometry, Photon; D000273:Adipose Tissue / Q000473:pathology; D000328:Adult; D000368:Aged; D000886:Anthropometry; D001823:Body Composition; D015519:Bone Density; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000378:metabolism* / Q000473:pathology*; D008297:Male; D008875:Middle Aged