title: [Remote results of conservative treatment of traumatic optic neuropathy].
abstract: The problem of pathogenesis and effective treatment of traumatic optic neuropathy (TON) is still an open question. According to current opinions the immediate results of conservative treatment with megadose corticosteroids are similar to those obtained with surgical decompression. No data on late results of both modes of treatment are at present available. This study was undertaken to assess the late results of conservative treatment of traumatic optic neuropathy. The clinical material comprised 15 patients (3 women and 12 men, age 14-64 years), who developed clinical symptoms of TON as a consequence of closed head trauma. All were treated conservatively with megadose steroid therapy. 10 patients presented to follow-up examination performed 3-11 years after the injury. A full ophthalmologic survey and colour-coded Doppler (CCD) examination of the orbital vessels were performed in all subjects. In 6 patients there was full blindness of the affected eye since the injury. Their visual acuity did not improve despite vigorous treatment and their eyes were still blind at the late follow-up examination. No flow found with CCD in their central retinal arteries at follow-up might suggest structural disruption of the nerve. In 5 of these patients ocular atrophy evolved between the injury and follow-up examination. 4 patients, who on admission displayed merely light sensation, responded to 2-3 weeks of steroid therapy with improvement of visual acuity to 3/50, 5/50, 5/10, 5/7. After 4-6 years however, visual acuity of all these patients deteriorated again to mere light perception in three and 1/50 in another one. Optic atrophy was diagnosed in all the affected eyes. Our results indicate that conservative treatment of TON, even if giving satisfactory relief of the symptoms, may not be reliable in permanent restrainment of the sequela of traumatic optic neuropathy.
authors.affiliation: Katedry Okulistyki Akademii Medycznej w Białymstoku.
authors.forename: Z
authors.initials: Z
authors.lastname: Mariak
authors.forename: Z
authors.initials: Z
authors.lastname: Mariak
authors.forename: I
authors.initials: I
authors.lastname: Obuchowska
authors.forename: A
authors.initials: A
authors.lastname: Stankiewicz
authors.forename: E
authors.initials: E
authors.lastname: Proniewska-Skretek
authors.forename: R
authors.initials: R
authors.lastname: Zalewska
mesh_terms: D000293:Adolescent; D000328:Adult; D001766:Blindness / Q000209:etiology; D005131:Eye Injuries / Q000188:drug therapy* / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D016489:Head Injuries, Closed / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020221:Optic Nerve Injuries; D012189:Retrospective Studies; D013256:Steroids / Q000627:therapeutic use*
chemical_list: D013256:Steroids