The utility of complete genome sequences in the study of pathogenic bacteria.
The availability of complete genome sequences is a revolution in the study of microorganisms. A fully annotated genome sequence provides an interactive tool for scientists and influences the approach and focus of research. In this article I discuss the impact of genome sequencing projects of bacteria. Much useful data have been obtained but the experimental methods needed to fully exploit the information continue to develop. Some of the approaches and particular applications relevant to bacteria of clinical importance are discussed.
Hood
D W
DW
University of Oxford Department of Paediatrics, John Radcliffe Hospital, Headington, UK.
D001419:Bacteria / Q000235:genetics / Q000472:pathogenicity*; D001424:Bacterial Infections / Q000188:drug therapy; D001428:Bacterial Vaccines; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D006193:Haemophilus influenzae / Q000235:genetics; D007255:Information Services; D014774:Virulence / Q000235:genetics
D001428:Bacterial Vaccines