Development of the Na+/H+ exchange inhibitor cariporide as a cardioprotective drug: from the laboratory to the GUARDIAN trial.
Scholz
W
W
Hoechst Marion Roussel, Frankfurt/Main, Germany.
Jessel
A
A
Albus
U
U
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D006146:Guanidines / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D017923:Sodium-Hydrogen Exchangers / Q000037:antagonists & inhibitors*; D013450:Sulfones / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use
D000889:Anti-Arrhythmia Agents; D006146:Guanidines; D017923:Sodium-Hydrogen Exchangers; D013450:Sulfones; C093373:cariporide