Cross-reactive antigens of Haemonchus contortus adult worms in Teladorsagia circumcincta infected goats.
The adult Haemonchus contortus somatic antigens responsible for cross-reactivity have been analysed using serum samples from goat kids infected and reinfected with Teladorsagia circumcincta. Goat kids infected with T. circumcincta had similar serum ELISA values against somatic antigens of H. contortus as goats infected with H. contortus itself. Immunoblotting confirmed this extensive cross-reactivity particularly in the molecular weight range 105-29 kDa. However, peptides with high (195, 152 and 119 kDa) or low (23 kDa) molecular weight were only faintly recognized by heterologous sera.
Molina
J M
JM
Departamento de Patología Animal (Parasitología y Enfermedades Parasitarias), Facultad de Veterinaria de la Universidad de Las Palmas de Gran Canaria, Grand Canary Island, Spain. molina@infovia.ulpgc.es
Ruiz
A
A
Rodríguez-Ponce
E
E
Gutiérrez
A C
AC
González
J
J
Hernández
S
S
D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D000917:Antibody Formation; D000947:Antigens, Helminth / Q000276:immunology*; D015153:Blotting, Western; D003429:Cross Reactions; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000469:parasitology; D015511:Goat Diseases / Q000276:immunology* / Q000469:parasitology*; D006041:Goats; D006189:Haemonchus / Q000276:immunology*; D007074:Immunoglobulin G / Q000097:blood; D007814:Larva; D010028:Ostertagia / Q000276:immunology*; D010029:Ostertagiasis / Q000276:immunology / Q000662:veterinary*; D010270:Parasite Egg Count / Q000662:veterinary; D013997:Time Factors
D000909:Antibodies, Helminth; D000947:Antigens, Helminth; D007074:Immunoglobulin G