title: Use of state hospital discharge data to assess the morbidity from rotavirus diarrhea and to monitor the impact of a rotavirus immunization program: A pilot study in Connecticut.
abstract: OBJECTIVE
  Now that rotavirus vaccines have been licensed and recommended for routine immunization of US infants, there is an urgent need for data to assess the morbidity from rotavirus diarrhea and to monitor the impact of a rotavirus immunization program. In a pilot study, we have assessed the usefulness of state hospital discharge data on diarrhea in children to provide this information by examining data from Connecticut.
  
  
  METHODS
  Retrospective analysis of discharge records from acute care, nongovernmental hospitals in Connecticut. Patients. Children 1 month through 4 years of age with a diarrhea-associated diagnosis listed on the discharge record. Setting. Connecticut, 1987 through 1996.
  
  
  RESULTS
  During the 10-year study period, a total of 11 324 diarrhea-associated hospitalizations (49.4 hospitalizations per 10,000 children) were reported. Diarrhea-associated hospitalizations peaked during February through April, especially among children 4 to 35 months of age. The seasonality and age distribution of diarrhea-associated hospitalizations of presumed noninfectious and viral etiologies resembled those of rotavirus-associated hospitalizations. During 1993 to 1996, rotavirus was coded for 10.4% of diarrhea-associated hospitalizations increasing from 8.6% in 1993 to 14.7% in 1996. The unadjusted median cost of a diarrhea-associated hospitalization during 1987 to 1996 and 1993 to 1996 was $1,941 and $2,428, respectively.
  
  
  CONCLUSIONS
  Diarrhea causes substantial morbidity in children from Connecticut. The winter seasonal peak of diarrhea-associated hospitalizations in children 4 to 35 months of age coinciding with the peak of rotavirus-specific hospitalizations suggests that rotavirus is an important contributor to the overall morbidity. Although our findings suggest incomplete coding of rotavirus cases, state hospital discharge data should provide sensitive and timely information to monitor the impact of a rotavirus immunization program in Connecticut.
authors.affiliation: Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. uap2@cdc.gov
authors.forename: U D
authors.initials: UD
authors.lastname: Parashar
authors.forename: M A
authors.initials: MA
authors.lastname: Chung
authors.forename: R C
authors.initials: RC
authors.lastname: Holman
authors.forename: R W
authors.initials: RW
authors.lastname: Ryder
authors.forename: J L
authors.initials: JL
authors.lastname: Hadler
authors.forename: R I
authors.initials: RI
authors.lastname: Glass
mesh_terms: D002675:Child, Preschool; D003237:Connecticut / Q000453:epidemiology; D003365:Costs and Cost Analysis; D003967:Diarrhea / Q000453:epidemiology / Q000517:prevention & control / Q000821:virology*; D003968:Diarrhea, Infantile / Q000453:epidemiology / Q000517:prevention & control / Q000821:virology*; D005260:Female; D006760:Hospitalization / Q000191:economics; D006801:Humans; D017589:Immunization Programs; D007223:Infant; D008297:Male; D009017:Morbidity; D010351:Patient Discharge / Q000706:statistics & numerical data; D010865:Pilot Projects; D012401:Rotavirus / Q000276:immunology; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000517:prevention & control*; D014765:Viral Vaccines / Q000008:administration & dosage*
chemical_list: D014765:Viral Vaccines