[State of energy metabolism and microsomal monooxygenases in animals exposed to inhaled 1,2,4-trimethylbenzene].
The investigations demonstrate that unfavourable changes occur in the tissues and red blood cells of the animals exposed to a single dose of 1,2,4-trimethylbenzene (TMB) in a concentration of 10 mg/m3; moreover, the inclusion of 32P is increased in the biochemical structures of the animals and the concentrations of Na, K, Mg, and Ca ions change. Exposure to TMB, 0.01-1.0 mg/m3 causes profound changes in the animals. Microsomal monooxygenases were found to activate in the lung, liver, and kidney of the animals exposed to TB in concentrations of 10 and 1 mg/m3.
Shakirov
D F
DF
Farkhutdinov
R R
RR
Zul'karnaev
T R
TR
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000395:Air Pollutants, Occupational / Q000633:toxicity*; D000818:Animals; D001081:Apyrase / Q000378:metabolism; D001555:Benzene Derivatives / Q000008:administration & dosage / Q000633:toxicity*; D004734:Energy Metabolism / Q000187:drug effects*; D019570:Inhalation Exposure; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D008861:Microsomes / Q000201:enzymology*; D009708:Nucleotidases / Q000378:metabolism; D051381:Rats
D000395:Air Pollutants, Occupational; D001555:Benzene Derivatives; C010313:pseudocumene; D009708:Nucleotidases; C018775:adenosine monophosphatase; D000251:Adenosine Triphosphatases; D001081:Apyrase