Possible anaphylactic reaction to abciximab.
We report a patient who experienced a severe anaphylactic reaction during coronary artery stenting. Subsequent to administration of a weight-adjusted dose of abciximab, the patient developed profound hypotension and severe, acute airway obstruction. The reaction was successfully reversed with a 16-hr infusion of epinephrine, steroids, and an H1 blocker. Cathet. Cardiovasc. Intervent. 48:71-73, 1999.
Guzzo
J A
JA
Department of Cardiology, University of North Carolina, Chapel Hill, North Carolina 27599, USA. jguzzo@email.unc.edu
Nichols
T C
TC
D000077284:Abciximab; D000707:Anaphylaxis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D000789:Angina, Unstable / Q000628:therapy; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D003331:Coronary Vessels; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000009:adverse effects*; D008875:Middle Aged; D015607:Stents
D000911:Antibodies, Monoclonal; D007140:Immunoglobulin Fab Fragments; D000077284:Abciximab