Therapeutic effects of moxibustion on experimental tumor.
This work investigated the therapeutic effects of the improved form of moxibustion (MT) on experimental tumor. Sarcoma 180 cells (1 x 10(7)) were transplanted into the subcutaneous tissue in the breast area of female ICR mice. Mice bearing a tumor were divided into one control and four experimental groups. The experimental groups were treated with MT for 1, 2, 3 and 4 times (abbreviated as MT1, MT2, MT3, MT4, respectively). This study showed that the experimental group treated with MT3 displayed the optimal therapeutic response. The longest mean survival time (87.8 days) within 120 days after treatment of MT3 significantly differed from the control group (60.2 days). In addition, uptake of 86Rb-radioactive tracer significantly decreased in tumors treated with MT3. The improved form of moxibustion used in this study is a reliable model of localized hyperthermia in tumor therapy.
Hau
D M
DM
Department of Life Science, National Tsing-Hua University, Hsinchu, Taiwan.
Lin
I H
IH
Lin
J G
JG
Chang
Y H
YH
Lin
C H
CH
D000818:Animals; D001831:Body Temperature / Q000502:physiology; D005260:Female; D000090023:Metallothionein 3; D051379:Mice; D008813:Mice, Inbred ICR; D009071:Moxibustion; D009368:Neoplasm Transplantation; D012414:Rubidium Radioisotopes; D012510:Sarcoma 180 / Q000473:pathology / Q000628:therapy*; D016019:Survival Analysis; D014407:Tumor Cells, Cultured
D000090023:Metallothionein 3; C000715430:Mt3 protein, mouse; D012414:Rubidium Radioisotopes