title: [Kallikrein-kinin system in acute empyema of pleura and pyopneumothorax].
abstract: In 56 patients with acute empyema of the pleura the level of aggregate kininogen and prekallikrein, free kallikrein and kininase activities in blood plasma and supernatant of pleural exudate were studied. It was established that epsilon-aminocapronic acid, contrykal and gordox suppress free kallikrein activity in the blood plasma and supernatant of pleural exudate. Intravenous and local application of proteolysis inhibitors resulted in improvement of the outcomes of the disease.
authors.forename: E A
authors.initials: EA
authors.lastname: Tseĭmakh
authors.forename: V N
authors.initials: VN
authors.lastname: Kurasov
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D016724:Empyema, Pleural / Q000188:drug therapy / Q000378:metabolism*; D005122:Exudates and Transudates / Q000378:metabolism; D005260:Female; D006801:Humans; D016234:Kallikrein-Kinin System / Q000187:drug effects / Q000502:physiology*; D007610:Kallikreins / Q000037:antagonists & inhibitors / Q000378:metabolism; D007704:Kininogens / Q000037:antagonists & inhibitors / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D011030:Pneumothorax / Q000188:drug therapy / Q000378:metabolism*; D015842:Serine Proteinase Inhibitors / Q000627:therapeutic use
chemical_list: D007704:Kininogens; D015842:Serine Proteinase Inhibitors; D007610:Kallikreins