Effect of oxidized fish oil and alpha-tocopherol on the peroxidation of erythrocyte membrane phospholipids in rats.
The effects of dietary oxidized fish oil and alpha-tocopherol on the thiobarbituric acid (TBA) values and phospholipid hydroperoxide levels of the erythrocyte membrane were studied in rats. No significant differences in the TBA values or phospholipid hydroperoxide levels of the membrane were observed between groups fed either oxidized fish oil or control diets. Furthermore, there were no marked differences in these values whether or not the groups were administered diets containing added alpha-tocopherol. These results suggest that the intake of oxidized fish oil and the supplementation with alpha-tocopherol do not influence the level of lipid peroxidation in the erythrocyte membrane.
Suzuki
H
H
National Food Research Institute, Tsukuba, Ibaraki, Japan.
Jang
H G
HG
Rhim
J H
JH
D000818:Animals; D004910:Erythrocyte Membrane / Q000187:drug effects* / Q000378:metabolism; D005395:Fish Oils / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D008563:Membrane Lipids / Q000097:blood*; D010084:Oxidation-Reduction; D010743:Phospholipids / Q000097:blood*; D051381:Rats; D017208:Rats, Wistar; D014810:Vitamin E / Q000494:pharmacology*
D005395:Fish Oils; D008563:Membrane Lipids; D010743:Phospholipids; D014810:Vitamin E