title: [Immunology of tuberculosis: current status].
abstract: The paper outlines the high-priority trends in basic and applied investigations of antituberculous immunity. It presents the results obtained from studies of the genetic mechanisms responsible for the control of susceptibility in experimental tuberculosis, from analyses of novel chemical and recombinant tuberculosis vaccines, from examinations of the role of immunological memory in the disease. While describing the results of tuberculosis immunodiagnosis, particular emphasis is laid on its major aspects: on the differential diagnosis of tuberculosis and other lung diseases and on the screening of high-risk group populations for disease progression in order to made further in-depth studies. Current aspects of evaluating the immune status and nonspecific responsiveness in patients with tuberculosis are considered.
authors.forename: V I
authors.initials: VI
authors.lastname: Litvinov
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Gergert
authors.forename: A M
authors.initials: AM
authors.lastname: Moroz
authors.forename: A S
authors.initials: AS
authors.lastname: Apt
authors.forename: V V
authors.initials: VV
authors.lastname: Eremeev
authors.forename: G A
authors.initials: GA
authors.lastname: Kosmiadi
authors.forename: N V
authors.initials: NV
authors.lastname: Kulikovskaia
authors.forename: I V
authors.initials: IV
authors.lastname: Liadova
authors.forename: B V
authors.initials: BV
authors.lastname: Nikoneko
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000818:Animals; D000995:Antitubercular Agents / Q000627:therapeutic use; D001500:BCG Vaccine / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D007109:Immunity; D007159:Immunologic Tests; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000276:immunology* / Q000517:prevention & control
chemical_list: D000276:Adjuvants, Immunologic; D000995:Antitubercular Agents; D001500:BCG Vaccine