Transient diabetes insipidus in a dog with acromegaly.
A nine-year-old female beagle with acromegaly and extreme polyuria and polydipsia during dioestrus is described. It was demonstrated that polyuria was related to an inadequate rise of arginine-vasopressin (AVP) levels after water deprivation and stimulation with hypertonic saline. Administration of AVP did not lead to a significant increase in urine osmolality or reduction of urine volume. Clinical signs, except for bony changes, completely disappeared following ovariohysterectomy.
Schwedes
C S
CS
Department of Small Animal Internal Medicine, Faculty of Veterinary Medicine, University of Giessen, Germany.
D000172:Acromegaly / Q000150:complications / Q000662:veterinary*; D000818:Animals; D001127:Arginine Vasopressin / Q000008:administration & dosage / Q000494:pharmacology; D003919:Diabetes Insipidus / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000209:etiology / Q000473:pathology*; D004285:Dogs; D004326:Drinking; D005260:Female; D007044:Hysterectomy / Q000009:adverse effects / Q000662:veterinary; D010052:Ovariectomy / Q000009:adverse effects / Q000662:veterinary; D011141:Polyuria / Q000209:etiology / Q000662:veterinary
D001127:Arginine Vasopressin