[Clinical results of cord blood transplantation].
Nearly 1000 cases have received cord blood transplantation in the world since the first successful transplantation by Gluckman. 79 cases have been reported to the Ministry of Health in Japan. Results of sibling transplantation have been good and the survival rates are as good as those in bone marrow transplantation. On the other hands, results of unrelated transplantation seem to be poor due to lower engraftment rate and higher transplant-related mortality. Number of attempts in adults is increasing, but the initial results do not look so good, probably because many transplants were done at the advanced stages, specially in adults. Further analysis and follow-up are needed for more accurate evaluation of this treatment modality.
Kato
S
S
Department of Pediatrics, Tokai University School of Medicine.
D000328:Adult; D005312:Fetal Blood; D006085:Graft Survival; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006801:Humans