title: Treatment of moderate mitral regurgitation and coronary disease by coronary bypass alone: late results.
abstract: BACKGROUND
  In cases of moderate mitral regurgitation and coronary artery disease operative strategy continues to be debated between coronary artery bypass grafting alone and concomitant valve replacement or repair. We previously reported on 58 patients with moderate mitral regurgitation who had coronary artery bypass grafting between 1977 and 1983. We present the late results for this original cohort (test group), and a matched control group of coronary artery bypass grafting patients without mitral regurgitation (n = 58).
  
  
  RESULTS
  In the original cohort, the hospital mortality rate was 3.4% (2 of 58), and 80.4% (45 of 56) of hospital survivors were alive at the time of initial follow-up (mean, 4.3+/-2.3 years). Hospital mortality in the control group was 6.9% (4 of 58 patients). Follow-up was 98.2% (108 of 110 patients) complete, with a mean follow-up time of 10.3+/-5.5 years. Kaplan-Meier curves for hospital survivors showed similar 5- and 10-year survival rates between the two groups (p = 0.59). On multivariate analysis, age 65 years or more, congestive heart failure class III or IV, and pulmonary capillary wedge pressure more than 17 mm Hg were significant (p < 0.05) independent predictors of diminished survival in the test group.
  
  
  CONCLUSIONS
  Patients with moderate mitral regurgitation and coronary artery disease treated solely with coronary artery bypass grafting had acceptable early and late results. Moderate mitral regurgitation at the time of revascularization does not always warrant operative correction.
authors.affiliation: Carlyle Fraser Heart Center, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia 30365-2225, USA.
authors.forename: I G
authors.initials: IG
authors.lastname: Duarte
authors.forename: Y
authors.initials: Y
authors.lastname: Shen
authors.forename: M J
authors.initials: MJ
authors.lastname: MacDonald
authors.forename: E L
authors.initials: EL
authors.lastname: Jones
authors.forename: J M
authors.initials: JM
authors.lastname: Craver
authors.forename: R A
authors.initials: RA
authors.lastname: Guyton
mesh_terms: D000368:Aged; D015331:Cohort Studies; D015897:Comorbidity; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000401:mortality / Q000601:surgery*; D011183:Postoperative Complications / Q000401:mortality; D015996:Survival Rate