title: Laryngeal scleroma.
abstract: Respiratory scleroma is a chronic, progressive granulomatous disease of the respiratory tract. The causal organism is the Klebsiella rhinoscleromatis. The disease has three stages: the initial catarrhal stage, granulomatous stage, and sclerotic stage. The object of this report was to determine the clinical behaviour of the laryngeal scleroma. The study included 17 patients with this manifestation characterized by airway obstruction and dysphonia. The report revealed that respiratory scleroma affected the larynx in 40%, and the principal findings were glottic/subglottic stenosis.
authors.affiliation: Department of Undergraduate Medical Education, Hospital General de México, Mexico.
authors.forename: G
authors.initials: G
authors.lastname: Fajardo-Dolci
authors.forename: R
authors.initials: R
authors.lastname: Chavolla
authors.forename: E
authors.initials: E
authors.lastname: Lamadrid-Bautista
authors.forename: J
authors.initials: J
authors.lastname: Rizo-Alvarez
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000209:etiology; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007818:Laryngeal Diseases / Q000150:complications / Q000473:pathology* / Q000628:therapy; D053685:Laser Therapy; D008297:Male; D012189:Retrospective Studies; D012226:Rhinoscleroma / Q000150:complications / Q000473:pathology* / Q000628:therapy; D014140:Tracheotomy; D016896:Treatment Outcome; D014832:Voice Disorders / Q000209:etiology
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin