title: A patient with rectal cancer associated with ulcerative colitis in whom endoscopic ultrasonography was useful for diagnosis.
abstract: Endoscopic ultrasonography (EUS) was helpful for the diagnosis of rectal cancer associated with ulcerative colitis. The patient was a 38-year-old Japanese man with a 19-year history of relapsing-remitting type ulcerative colitis involving the entire colon. Routine colonoscopy revealed multiple polypoid prominences in the upper portion of the rectum. EUS revealed a hypoechoic mass in the submucosa beneath and around the polypoid lesion on the most oral side. Signet ring cells were found in a biopsy specimen from this lesion. Subtotal colectomy was performed. A depressed lesion was observed around the prominence on the most oral side; histologically, this lesion was poorly differentiated mucinous and signet ring cell carcinoma extending into the subserosa. The polypoid lesion on the most anal side was well differentiated adenocarcinoma, which was limited to the mucosa. Our findings suggest that EUS is helpful for detecting invasive cancer associated with ulcerative colitis.
authors.affiliation: Department of Gastroenterology, Kyoto First Red Cross Hospital, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Shimizu
authors.forename: S
authors.initials: S
authors.lastname: Myojo
authors.forename: M
authors.initials: M
authors.lastname: Nagashima
authors.forename: Y
authors.initials: Y
authors.lastname: Okuyama
authors.forename: N
authors.initials: N
authors.lastname: Sugeta
authors.forename: S
authors.initials: S
authors.lastname: Sakamoto
authors.forename: H
authors.initials: H
authors.lastname: Kutsumi
authors.forename: H
authors.initials: H
authors.lastname: Otsuka
authors.forename: Y
authors.initials: Y
authors.lastname: Suyama
authors.forename: S
authors.initials: S
authors.lastname: Fujimoto
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000000981:diagnostic imaging*; D000328:Adult; D001466:Barium Sulfate; D018279:Carcinoma, Signet Ring Cell / Q000150:complications / Q000000981:diagnostic imaging*; D003093:Colitis, Ulcerative / Q000150:complications*; D003113:Colonoscopy; D019160:Endosonography; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000150:complications / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D011859:Radiography; D012004:Rectal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging*
chemical_list: D001466:Barium Sulfate