Viral-induced neurodegenerative disease.
Viral etiology has been postulated in a variety of neurological diseases in humans, including multiple sclerosis. Several experimental animal models of viral-induced neurodegenerative disease provide insight into potential host- and pathogen-dependent mechanisms involved in the disease process. Two such mouse models are the Theiler's murine encephalomyelitis virus (TMEV) infection and mouse hepatitis virus (MHV) infection.
Buchmeier
M J
MJ
The Scripps Research Institute, 10550 North Torrey Pines Road, CVN-8, La Jolla, CA 92037, USA. buchm@scripps.edu
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D000818:Animals; D006801:Humans; D019636:Neurodegenerative Diseases / Q000276:immunology / Q000821:virology*; D014777:Virus Diseases / Q000276:immunology*; D014780:Viruses / Q000276:immunology*