title: Cerebral blood flow velocity during repeatedly induced ventricular fibrillation.
abstract: OBJECTIVE
  To investigate the effect of induced ventricular fibrillation and defibrillation on cerebral blood flow (CBF) was investigated using a transcranial Doppler.
  
  
  METHODS
  Prospective clinical study.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  12 ASA physical status III and IV patients who underwent implantable cardioverter defibrillator placement during general anesthesia.
  
  
  METHODS
  Cerebral blood flow velocity was measured repeatedly during induced ventricular fibrillation and subsequent defibrillation.
  
  
  RESULTS
  The mean flow velocity in the middle cerebral artery was measured using a transcranial Doppler. The mean flow velocities decreased significantly immediately after ventricular fibrillation was induced, but they returned to preventricular fibrillation levels immediately after successful defibrillation. Repeatedly induced ventricular fibrillations have no cumulative detrimental effect on the CBF velocity.
  
  
  CONCLUSIONS
  Repetitively induced ventricular fibrillation and defibrillation during the insertion of implantable cardioverter defibrillator did not show any detrimental changes in CBF. Transcranial Doppler may be a more sensitive device than other currently available cerebral monitors to detect changes in cerebral circulation during a brief episode of ventricular fibrillation and defibrillation.
authors.affiliation: Department of Anesthesiology, St. Louis University Health Sciences Center, MO, USA.
authors.forename: K T
authors.initials: KT
authors.lastname: Gopalan
authors.forename: J
authors.initials: J
authors.lastname: Lee
authors.forename: S
authors.initials: S
authors.lastname: Ikeda
authors.forename: C M
authors.initials: CM
authors.lastname: Burch
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology; D002536:Cerebral Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000502:physiology*; D017147:Defibrillators, Implantable; D004554:Electric Countershock / Q000295:instrumentation; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013997:Time Factors; D017585:Ultrasonography, Doppler, Transcranial; D014693:Ventricular Fibrillation / Q000503:physiopathology* / Q000628:therapy