Clinical surveillance of a tined, bipolar, J-shaped, steroid-eluting, silicone-insulated atrial pacing lead.
Since 1990, 558 Medtronic 5524 bipolar, silicone-insulated, J-shaped, tined, steroid-eluting atrial leads have been implanted at the Mayo Clinic (Rochester, MN, USA) and the Midelfort Clinic (Eau Claire, WI, USA). Implantation data were favorable, with pacing thresholds at implantation (median threshold, 0.6 V) better than most published data on other atrial leads. The rate of acute lead-related complications (dislodgment and diaphragmatic pacing) necessitating reoperation or electrical abandonment of the atrial lead was 0.9%. This rate is lower than that in most published series of atrial leads. Over a median follow-up time of 17.5 months (up to 69 months), there were no chronic lead-related complications and no definite or suspected failures of lead material. This rate is much lower than that with other atrial leads studied previously. We conclude that the Medtronic 5524 atrial lead combines the reliability of silicone insulation with a lack of chronic complications and high thresholds due to its steroid elution and with stability in the atrium due to its J shape despite a passive fixation mechanism. There is no evidence of lead material failure during up to 6 years of follow-up.
Glikson
M
M
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.
Hyberger
L K
LK
Hitzke
M K
MK
Kincaid
D K
DK
Hayes
D L
DL
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D020099:Coated Materials, Biocompatible; D003907:Dexamethasone / Q000008:administration & dosage*; D004562:Electrocardiography; D004567:Electrodes, Implanted; D019544:Equipment Failure Analysis; D005500:Follow-Up Studies; D005938:Glucocorticoids; D006801:Humans; D010138:Pacemaker, Artificial; D011358:Product Surveillance, Postmarketing; D015203:Reproducibility of Results; D012828:Silicones; D013686:Telemetry
D000893:Anti-Inflammatory Agents; D020099:Coated Materials, Biocompatible; D005938:Glucocorticoids; D012828:Silicones; D003907:Dexamethasone