title: Overactive detrusor.
abstract: Detrusor overactivity poses a major challenge to physicians from many specialities. Progress in our understanding of the pathogenesis of detrusor overactivity is slow but steady. Advances in treatment continue to be made, both with new agents and new methods of delivering older drugs. Neuromodulation is showing great promise as experience increases, and developments in bladder augmentation offer hope for lower morbidity treatments in future.
authors.affiliation: Department of Urology, Bristol Urological Institute, Southmead Hospital, UK. edu@bui.ac.uk
authors.forename: J
authors.initials: J
authors.lastname: Sullivan
authors.forename: P
authors.initials: P
authors.lastname: Abrams
mesh_terms: D000818:Animals; D005260:Female; D006801:Humans; D008297:Male; D009130:Muscle, Smooth / Q000187:drug effects / Q000294:innervation / Q000503:physiopathology*; D012307:Risk Factors; D013119:Spinal Cord Injuries / Q000503:physiopathology; D001745:Urinary Bladder Diseases / Q000503:physiopathology* / Q000628:therapy*; D014555:Urination Disorders / Q000503:physiopathology* / Q000628:therapy*