The spectrum of imaging in Currarino triad.
The aim of this study was to evaluate the spectrum of findings and the efficacy of different imaging modalities in order to formulate recommendations for diagnostic imaging of Currarino triad (ASP syndrome), including screening of relatives. The imaging films of five female patients (age range 6 weeks to 12 months) were analysed retrospectively. The studied material consisted of US and MRI of the lower spine (5 patients each), lumbosacral plain radiography (4 patients), contrast enema (4 patients), urinary US (2 patients), genitography (1 patient) and myelo-CT (1 patient). Depiction of pathological findings with different imaging modalities was reviewed and validated with special respect to their demonstrability by US. Ultrasonography detected the sacral bony defect as well as the presacral pathology (meningocele and/or tumour) and thereby gave the basic diagnosis in all of the cases. It also depicted tethered cord and urinary tract abnormalities correctly. Magnetic resonance imaging gave a more distinct visualization of pre- and intraspinal pathology with additional demonstration of intraspinal lipoma in two cases. Regarding anorectal and genital malformations, radiographic contrast agent studies had been used in all patients. Two blind-ending retrorectal fistulas, depicted by enema, were missed by MRI. Patients with congenital or early infancy obstipation, anorectal malformations and complex urinary tract malformations should have spinal and pelvic sonography first. A plain film of the sacrum is recommended in equivocal cases. The need for MRI and contrast agent studies depends on the individual pathology, whereas presently MRI has made further radiographic imaging increasingly dispensable. A screening program with lumbosacral US or plain radiography for families with Currarino triad should be obligatory.
Riebel
T
T
Abteilung für Pädiatrische Radiologie, Strahlenklinik und Poliklinik, Charité, Campus Virchow Klinikum, Humboldt Universität Berlin, Augustenburger Platz 1, D-13353 Berlin, Germany.
Mäurer
J
J
Teichgräber
U K
UK
Bassir
C
C
D000015:Abnormalities, Multiple / Q000175:diagnosis* / Q000235:genetics; D001006:Anus, Imperforate / Q000175:diagnosis* / Q000235:genetics; D002675:Child, Preschool; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D007223:Infant; D008588:Meningocele / Q000175:diagnosis* / Q000235:genetics; D012447:Sacrum / Q000002:abnormalities / Q000473:pathology; D013577:Syndrome