Clinical use of topical retinaldehyde on photoaged skin.
BACKGROUND
Retinaldehyde, the natural precursor of retinoic acid, should exert similar effects on photoaged skin.


OBJECTIVE
To establish the efficacy and safety of topical retinaldehyde on photoaged skin.


METHODS
Open and controlled clinical studies using image analysis of silicone skin replicas.


RESULTS
Retinaldehyde proved efficient and safe.


CONCLUSIONS
Retinaldehyde is efficient and well tolerated for the improvement of the signs of photoaging.
Creidi
P
P
Department of Dermatology, Hôpital Saint-Jacques, Besançon, France.
Humbert
P
P
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008875:Middle Aged; D012172:Retinaldehyde / Q000008:administration & dosage*; D015595:Skin Aging / Q000187:drug effects*
D012172:Retinaldehyde