Genetic counseling for BRCA1/BRCA2 testing.
Genetic counseling plays a key role in the BRCA1/BRCA2 testing process. The initial genetic counseling encounter will determine the appropriateness of the test by collecting a detailed family history and determining the likelihood that the family has a BRCA1 or BRCA2 mutation. Once the test is offered, then genetic counseling discussions center around the possible test results, implications of the results to the patient and other relatives, and risks and benefits of testing. The goal of this pre-test genetic counseling session is to ensure that patients have sufficient information with which to make a decision about being tested. At results disclosure, individuals can learn their results along with information about cancer risks and medical management options. Follow-up genetic counseling services can provide continued support and help arrange consultations with other medical care providers as needed. All clinical BRCA1/BRCA2 testing programs should include pre- and post-test genetic counseling.
Schneider
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Dana-Farber Cancer Institute, Boston, MA 02115, USA.
D024682:BRCA2 Protein; D001943:Breast Neoplasms / Q000235:genetics / Q000517:prevention & control / Q000523:psychology; D004252:DNA Mutational Analysis; D005260:Female; D019398:Genes, BRCA1; D016147:Genes, Tumor Suppressor; D005817:Genetic Counseling; D005820:Genetic Testing; D006801:Humans; D009154:Mutation; D009363:Neoplasm Proteins / Q000235:genetics*; D010051:Ovarian Neoplasms / Q000235:genetics / Q000517:prevention & control / Q000523:psychology; D012307:Risk Factors; D014157:Transcription Factors / Q000235:genetics*
D024682:BRCA2 Protein; D009363:Neoplasm Proteins; D014157:Transcription Factors