title: Median and ulnar palm-wrist studies.
abstract: OBJECTIVE
  Routine carpal tunnel electrodiagnosis frequently includes median (MPW) and ulnar (UPW) palm-wrist mixed nerve conduction latency determinations over 8 cm. Despite widespread use, normative palmar latency difference (PLD) and UPW values, and the relative utility of onset latency (OL) or peak latency (PL) measurements are controversial. The current study was conducted to determine normative values for these parameters.
  
  
  METHODS
  MPW and UPW studies were performed unilaterally in 33 normal controls. The PLD-OL and PLD-PL were calculated. The mean, range, standard deviation, and upper limits of normal were determined. 74 hands (50 patients) with both clinical and electrophysiologic median neuropathy were also studied.
  
  
  RESULTS
  The abnormal MPW and UPW cut-offs were both 1.8 ms (OL), and 2.3 ms (PL). The abnormal PLD cut-offs were 0.5 ms (OL and PL). Using either OL or PL, PLD parameters were similar within controls, and also within CTS patients. Using either OL or PL, UPW parameters were similar between controls and CTS patients.
  
  
  CONCLUSIONS
  An abnormal PLD cut-off of 0.5 is recommended. This is slightly higher than some prior recommendations, however it should minimize the likelihood of false positive studies. Onset and peak latency measurements are likely to have similar clinical utility.
authors.affiliation: Department of Neurology, Saint Vincents Hospital of New York, NY 10011, USA.
authors.forename: H W
authors.initials: HW
authors.lastname: Sander
authors.forename: C
authors.initials: C
authors.lastname: Quinto
authors.forename: P B
authors.initials: PB
authors.lastname: Saadeh
authors.forename: S
authors.initials: S
authors.lastname: Chokroverty
mesh_terms: D000328:Adult; D000368:Aged; D002349:Carpal Tunnel Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D004576:Electromyography; D006801:Humans; D008475:Median Nerve / Q000502:physiology*; D008875:Middle Aged; D009431:Neural Conduction / Q000502:physiology; D014459:Ulnar Nerve / Q000502:physiology*; D014953:Wrist / Q000502:physiology*