Cisatracurium and atracurium as antigens.
Seventy-five consecutive patients referred to an anaesthetic allergy clinic were intradermally tested with atracurium and cisatracurium. With the exception of one patient the results were identical, suggesting that allergy to either drug is associated with allergy to the stereoisomer. For skin testing for allergy to neuromuscular blocking drugs it is only necessary to use either atracurium or cisatracurium and cisatracurium is the preferred drug.
Fisher
M M
MM
Department of Anaesthesia and Medicine, University of Sydney, New South Wales.
D000485:Allergens; D000707:Anaphylaxis / Q000139:chemically induced*; D000941:Antigens; D001279:Atracurium / Q000009:adverse effects* / Q000031:analogs & derivatives* / Q000276:immunology; D004342:Drug Hypersensitivity / Q000175:diagnosis; D005260:Female; D006801:Humans; D008875:Middle Aged; D009466:Neuromuscular Blocking Agents / Q000009:adverse effects* / Q000276:immunology; D003473:Neuromuscular Nondepolarizing Agents / Q000009:adverse effects / Q000276:immunology; D012882:Skin Tests
D000485:Allergens; D000941:Antigens; D009466:Neuromuscular Blocking Agents; D003473:Neuromuscular Nondepolarizing Agents; D001279:Atracurium; C101584:cisatracurium