title: Sonographic diagnosis of intrauterine growth restriction (IUGR) by fetal transverse cerebellar diameter (TCD)/abdominal circumference (AC) ratio.
abstract: OBJECTIVE
  To evaluate the validity of TCD/AC ratio in predicting IUGR.
  
  
  METHODS
  Prospective descriptive analysis.
  
  
  METHODS
  Maharaj Nakorn Chiang Mai Hospital, Chiang Mai University.
  
  
  METHODS
  Women meeting the inclusion criteria consisting of: (1) singleton pregnancies after 28 weeks of gestation; (2) known accurate gestational age; and (3) clinically suspected IUGR.
  
  
  METHODS
  The patients were sonographically examined for TCD/AC ratio. The best cut-off value of TCD/AC ratio in predicting IUGR was determined by a receiver operating characteristic (ROC) curve. The fetus with a TCD/AC ratio greater than the cut-off value would be antenatally diagnosed as IUGR for every gestational week. Standard definition of IUGR was a low birthweight, less than the 10th percentile.
  
  
  RESULTS
  One hundred and sixty-seven pregnancies with suspected IUGR were analyzed. The prevalence of IUGR among the study group was 51.5%. The best cut-off value of the TCD/AC ratio for predicting IUGR was 15.4%, giving the sensitivity, specificity, positive predictive value and negative predictive value of 73.26%, 80.25%, 79.75%, and 73.86%, respectively.
  
  
  CONCLUSIONS
  The sonographic fetal TCD/AC ratio as a gestational age-independent method can be helpful in antenatal diagnosis of IUGR, especially in pregnancy with uncertain gestational age.
authors.affiliation: Department of Obstetrics and Gynecology, Chiang Mai University, Thailand.
authors.forename: T
authors.initials: T
authors.lastname: Tongsong
authors.forename: C
authors.initials: C
authors.lastname: Wanapirak
authors.forename: T
authors.initials: T
authors.lastname: Thongpadungroj
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging* / Q000196:embryology; D000886:Anthropometry; D002531:Cerebellum / Q000000981:diagnostic imaging* / Q000196:embryology; D005314:Embryonic and Fetal Development; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging*; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D011446:Prospective Studies; D012372:ROC Curve; D012016:Reference Values; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal