title: Mortality in young adults in England and Wales: the impact of the HIV epidemic.
abstract: OBJECTIVE
  To quantify the contribution of the HIV epidemic to premature mortality in England and Wales 1985-1996.
  
  
  METHODS
  Surveillance of deaths in HIV-infected individuals and causes of death from death certificates.
  
  
  METHODS
  Time trends in age-specific mortality rates among 15-44 year olds and years of potential life lost (YPLL) to age 65 associated with HIV infection and other important causes of death in young adults.
  
  
  RESULTS
  The crude age-specific mortality rates for all causes of death in the 15-44 year age band remained fairly constant between 1985 and 1996: in other age bands a decrease was seen. Deaths from both suicide and HIV increased in men aged 15-44 years. Although suicide accounted for a greater number of deaths throughout the period investigated, the largest proportional and absolute increase was seen for deaths in HIV-infected people. By 1996, the contribution of HIV to YPLL to age 65 varied from less than 0.5% in most rural localities to 20% of total YPLL in one London health authority.
  
  
  CONCLUSIONS
  While part of the adverse trend in mortality in younger adults since 1985 was attributable to suicide, most resulted from HIV infection. The impact of HIV infection on mortality was greatest in London.
authors.affiliation: PHLS AIDS and STD Centre, Communicable Diseases Surveillance Centre, London, UK.
authors.forename: G
authors.initials: G
authors.lastname: Nylén
authors.forename: J
authors.initials: J
authors.lastname: Mortimer
authors.forename: B
authors.initials: B
authors.lastname: Evans
authors.forename: N
authors.initials: N
authors.lastname: Gill
mesh_terms: D000293:Adolescent; D000328:Adult; D002423:Cause of Death; D005260:Female; D015658:HIV Infections / Q000401:mortality; D006801:Humans; D008297:Male; D009026:Mortality / Q000639:trends*; D006113:United Kingdom / Q000453:epidemiology; D026712:Value of Life