Simultaneous determination of trace benzodiazepines from drinks by using direct electrospray probe/mass spectrometry (DEP/MS).
This study presents a novel means of rapidly determining benzodiazepines in various drinks. Electrospray mass spectrometry with a direct probe design is used as the analytical instrument. Samples are treated only by a simple liquid-liquid extraction prior to direct electrospray probe/mass spectrometry (DEP/MS) analysis. The proposed method provides a relatively easy and efficient means of identifying the drugs in a very short time interval. On average, sample analysis is completed in less than five minutes including sample pretreatment. It is especially useful in forensic science since the technology can provide a rapid identification for unknown samples. Thus, the method proposed herein is highly appropriate for rapidly screening a large number of samples.
Chen
Y C
YC
Institute of Toxicology, Tzu Chi College of Medicine and Humanities, Hualien, Taiwan.
Hu
A
A
D001515:Beer / Q000032:analysis; D001569:Benzodiazepines / Q000032:analysis*; D001628:Beverages / Q000032:analysis*; D002253:Carbonated Beverages / Q000032:analysis; D002957:Citrus; D005554:Forensic Medicine / Q000379:methods; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods*; D013662:Tea / Q000737:chemistry
D013662:Tea; D001569:Benzodiazepines