title: [Implantation of a dual chamber pacemaker-defibrillator (DDD-ICD) in a patient with hypertrophic obstructive cardiomyopathy].
abstract: A 70-year-old woman with severely symptomatic hypertrophic obstructive cardiomyopathy was unresponsive to drug treatment. She had recurrent ventricular tachyarrhythmias and syncope and was at high risk for sudden death; a dual chamber pacemaker defibrillator (DDD-ICD) was implanted. Her initial left ventricular outflow tract gradient was 80 mm Hg and fell to 40 mm Hg during dual-chamber pacing at an atrial ventricular delay of 140 ms. In the follow-up over six months she was asymptomatic with respect to angina pectoris; ventricular tachycardias could be successfully terminated by antitachycardia pacing or by shocks. A dual chamber pacemaker defibrillator is an important therapeutic option for patients with symptomatic hypertrophic obstructive cardiomyopathy and ventricular tachyarrhythmias.
authors.affiliation: Abteilung Innere Medizin III, Universitätsklinikum Tübingen.
authors.forename: H R
authors.initials: HR
authors.lastname: Neuberger
authors.forename: C
authors.initials: C
authors.lastname: Mewis
authors.forename: V
authors.initials: V
authors.lastname: Dörnberger
authors.forename: R F
authors.initials: RF
authors.lastname: Bosch
authors.forename: V
authors.initials: V
authors.lastname: Kühlkamp
mesh_terms: D000368:Aged; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis / Q000628:therapy*; D016757:Death, Sudden, Cardiac / Q000517:prevention & control; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D004867:Equipment Design; D005260:Female; D006801:Humans; D010138:Pacemaker, Artificial; D013575:Syncope / Q000209:etiology; D017180:Tachycardia, Ventricular / Q000175:diagnosis / Q000628:therapy*