title: Deep vein thrombosis and pulmonary embolism prophylaxis in joint replacement surgery.
abstract: Joint replacement surgery is one of the most frequently performed procedures in the United States. The incidence of deep vein thrombosis and pulmonary embolism is very high in patients not receiving prophylaxis for the prevention of this postoperative complication. In this article, the current modalities for prophylaxis are reviewed with respect to their safety and efficacy. Recommendations that have been substantiated by evidence-based information are provided.
authors.affiliation: Department of Medicine, Thomas Jefferson University Hospital and Jefferson Medical College, Philadelphia, Pennsylvania, USA.
authors.forename: G J
authors.initials: GJ
authors.lastname: Merli
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D019643:Arthroplasty, Replacement / Q000009:adverse effects*; D019317:Evidence-Based Medicine; D006801:Humans; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control; D011655:Pulmonary Embolism / Q000209:etiology / Q000517:prevention & control*; D012216:Rheumatic Diseases / Q000150:complications / Q000601:surgery*; D018570:Risk Assessment; D020246:Venous Thrombosis / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000925:Anticoagulants