title: Expression of GATA-2 in the developing avian rhombencephalon.
abstract: Here we describe the expression pattern of GATA-2 in the developing chick hindbrain. We found that during the early period of neurogenesis this gene specifically labels a particular neuronal subtype, the contralateral vestibular-acoustic neurons of rhombomere 4, and that expression of this gene in these cells is transient. We also found that GATA-2 labels a broader territory of the ventral neural tube at later stages. As well as this hindbrain expression, we also describe expression of GATA-2 in the otic vesicle, oculomotor nucleus, third nerve and metanephros.
authors.affiliation: Department of Developmental Neurobiology, Kings College London, UK.
authors.forename: E
authors.initials: E
authors.lastname: Bell
authors.forename: A
authors.initials: A
authors.lastname: Lumsden
authors.forename: A
authors.initials: A
authors.lastname: Graham
mesh_terms: D000818:Animals; D002642:Chick Embryo; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000378:metabolism; D005123:Eye / Q000196:embryology / Q000378:metabolism; D050989:GATA2 Transcription Factor; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000276:immunology / Q000378:metabolism; D060850:LIM-Homeodomain Proteins; D009046:Motor Neurons / Q000378:metabolism; D009419:Nerve Tissue Proteins; D012249:Rhombencephalon / Q000196:embryology* / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics* / Q000276:immunology / Q000378:metabolism
chemical_list: D004268:DNA-Binding Proteins; D050989:GATA2 Transcription Factor; D018398:Homeodomain Proteins; C091135:Isl-2 protein, vertebrate; D060850:LIM-Homeodomain Proteins; D009419:Nerve Tissue Proteins; D014157:Transcription Factors; C063843:insulin gene enhancer binding protein Isl-1