title: [Critical appraisal of treatments in emergency settings].
abstract: A critical appraisal was carried out of treatment with high-dose epinephrine (HDE) in cardiopulmonary resuscitation (CPR), active compression and decompression CPR (ACD-CPR), military antishock trousers (MAST), and Continuous renal replacement therapy (CRRT) in the emergency setting, based on evidence-based medicine. Although the pathophysiological rationale encourage the clinical application of these treatments to improve the long-term outcome (mortality), no clinical trial could confirm their benefit. Additionally, Japanese investigators have reported no clinical epidemiological study related to this issue. Thus a clinicoepidemiological study associated with treatments in critical settings is required in this country.
authors.affiliation: Department of Emergency Medicine/ICU, Nagoya University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
authors.forename: J
authors.initials: J
authors.lastname: Takezawa
authors.forename: T
authors.initials: T
authors.lastname: Fukuoka
authors.forename: T
authors.initials: T
authors.lastname: Mayumi
mesh_terms: D004630:Emergencies; D004837:Epinephrine / Q000008:administration & dosage*; D019317:Evidence-Based Medicine; D005676:Gravity Suits; D006801:Humans; D017582:Renal Replacement Therapy; D012151:Resuscitation / Q000379:methods*
chemical_list: D004837:Epinephrine