[The reinnervation of skeletal muscles].
Experiments were conducted to study different methods of reinnervation of predenervated muscle, for which purpose three groups of animals were used. The first group (reinnervation as to Brunelli) served as a kind of control. In the second group, side notches were cut in the nerve-neurotizator before inserting it into the muscle, in the third group, endomysium and perimysium were defibered at the site of insertion into the muscle of the nerve-neurotizator. The obtained results showed that in the second and third groups processes of reinnervation proceed faster by far and in a more efficient way. This is because the nerve-neurotizator has side cuttings in it, which fact promotes the ingrowth into the muscle tissue of a great many of nerve conductors, and because the skeletal muscle neurotropism gets enhanced at the expense of the connective tissue being formed in sites of defiberation of endomysium and perimysium. The secured results permit recommending the proposed ways and means for reinnervation of denervated muscles in a clinical setting as more efficacious than that by Brunelli.
Kostinskiĭ
G B
GB
D000818:Animals; D008297:Male; D018482:Muscle, Skeletal / Q000033:anatomy & histology / Q000294:innervation* / Q000601:surgery; D009416:Nerve Regeneration; D016067:Nerve Transfer / Q000379:methods; D051381:Rats; D013536:Suture Techniques; D013997:Time Factors