title: Antiinflammatory effect of the aqueous extract from Rumex patientia L. roots.
abstract: Pharmacological studies were conducted with the aqueous extract of roots of Rumex patientia L. (Polygonaceae) on experimental animals. For evaluating the antiinflammatory activity, carrageenan, histamine, dextrane, serotonine formaldehyde-induced oedema tests, cotton-pellet granuloma, and Kabak tests in rats were used. The extract was found to possess antiinflammatory activity. Acute toxicity studies revealed that the extract up to a dose of 3 mg/kg orally was nontoxic.
authors.affiliation: Department of Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Süleyman
authors.forename: L O
authors.initials: LO
authors.lastname: Demirezer
authors.forename: A
authors.initials: A
authors.lastname: Kuruüzüm
authors.forename: Z N
authors.initials: ZN
authors.lastname: Banoğlu
authors.forename: F
authors.initials: F
authors.lastname: Göçer
authors.forename: G
authors.initials: G
authors.lastname: Ozbakir
authors.forename: A
authors.initials: A
authors.lastname: Gepdiremen
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000009:adverse effects / Q000494:pharmacology*; D007249:Inflammation / Q000139:chemically induced / Q000188:drug therapy*; D008297:Male; D010936:Plant Extracts / Q000009:adverse effects / Q000494:pharmacology*; D019664:Polygonaceae / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000893:Anti-Inflammatory Agents; D010936:Plant Extracts