[Spasmodic torticollis: experience of 5 years with botulinum toxin treatment].
64 cases with spasmodic torticollis were observed during 5 years and treated with botulinum toxin (BTX). BTX was injected into dystonic muscles mostly into sternocleidomastoid then--trapezius, and splenius capitis muscle. Improvement (excellent, good and fair) was achieved in 40 patients (62%). Lack of information about 6 patient (9%). Injections were repeated every 3-4 months and in several cases even 1-2 during the year. After several injections atrophy and denervation potentials in EMG were observed in the majority of injected muscles. Neurotic syndromes coexisting with dystonia had worsening influence on therapeutic effects. Adverse events were observed in 5 cases. Treatment with BTX is very simple, easy, harmless and can be administered in outpatients.
Domzał
T M
TM
Kliniki Neurochirurgicznej Centralnego Szpitala Klinicznego Wojskowej Akademii Medycznej w Warszawie.
D000328:Adult; D000368:Aged; D001905:Botulinum Toxins / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009128:Muscle Spasticity / Q000150:complications* / Q000503:physiopathology*; D009334:Neck Muscles / Q000503:physiopathology*; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D012189:Retrospective Studies; D013997:Time Factors; D014103:Torticollis / Q000150:complications* / Q000188:drug therapy*
D009465:Neuromuscular Agents; D001905:Botulinum Toxins