[Radiation-induced morphea].
Although the aetiology of morphea often remains unknown, various precipitating causes have been identified. Morphea is a rare development following irradiation. We observed a circumscribed scleroderma 14 years after x-ray-radiotherapy following surgery of breast cancer. Furthermore multiple weeping papules occurred within the radiation area. A relapse of the breast cancer was ruled out by histological examination which displayed a transepidermal elimination of acid mucin. The irradiation had obviously induced different reactions of the dermal fibroblasts (radiodermatitis, morphea, mucin production).
Fischer
M
M
Klinik und Poliklinik für Hautkrankheiten der Martin Luther-Universität Halle-Wittenberg.
Bormann
G
G
Wohlrab
J
J
Marsch
W C
WC
D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000627:therapeutic use; D008875:Middle Aged; D011701:PUVA Therapy; D012594:Scleroderma, Localized / Q000188:drug therapy / Q000209:etiology* / Q000532:radiotherapy; D014965:X-Rays / Q000009:adverse effects
D006821:Hyaluronoglucosaminidase