Adherence of albunex to an apical left ventricular thrombus.
A previously unrecognized left ventricular thrombus developed a distinct echogenic rim after intravenous injection of albumin microbubbles despite no visible opacification of the left-sided chambers. Absence of visible left ventricular opacification suggests a low density of microbubbles crossing the pulmonary vasculature and a high affinity of the microbubbles for the thrombus or its endothelial surface. These findings support previous observations that albumin microbubbles demonstrate transient adherence to abnormal endothelium.
Bach
D S
DS
Department of Internal Medicine, University of Michigan, Ann Arbor 48109, USA. dbach@umich.edu
D000418:Albumins; D003287:Contrast Media; D006331:Heart Diseases / Q000000981:diagnostic imaging*; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008863:Microspheres; D008875:Middle Aged; D013927:Thrombosis / Q000000981:diagnostic imaging*; D014463:Ultrasonography
D000418:Albumins; C060687:Albunex; D003287:Contrast Media