Striae formation in two HIV-positive persons receiving protease inhibitors.
Steroidal side effects such as "buffalo hump" and visceral abdominal fat accumulation have been reported in association with protease inhibitors. We report two cases of severe disfiguring striae formation in patients with HIV who recently started indinavir therapy. These changes occurred within 3 months of starting treatment.
Darvay
A
A
Department of Dermatology, Ealing Hospital, London, United Kingdom.
Acland
K
K
Lynn
W
W
Russell-Jones
R
R
D004359:Drug Therapy, Combination; D005260:Female; D017320:HIV Protease Inhibitors / Q000009:adverse effects*; D006679:HIV Seropositivity / Q000150:complications* / Q000188:drug therapy / Q000208:ethnology / Q000473:pathology; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000139:chemically induced* / Q000208:ethnology / Q000473:pathology; D014454:Uganda / Q000208:ethnology
D017320:HIV Protease Inhibitors