Acute hypersensitivity reactions to chemotherapy.
OBJECTIVE
To provide a review of the immune system response involved in acute hypersensitivity reactions (HSRs) and anaphylactic reactions to chemotherapy.


METHODS
Professional experience, published articles, and book chapters.


CONCLUSIONS
Acute HSRs from chemotherapy administration can be a rare to moderate occurrence, depending on the chemotherapy agents involved. It is of vital importance for nurses caring for patients receiving chemotherapy to take steps to prevent HSRs when possible and/or to minimize the potentially fatal effects of those reactions.


CONCLUSIONS
Nurses caring for patients receiving chemotherapy should understand the risk of HSRs as well as the pathophysiology involved to ensure utilization of preventive measures when appropriate and early recognition and intervention in the event of an acute HSR.
Labovich
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TM
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D018269:Carcinoma, Endometrioid / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage; D004342:Drug Hypersensitivity / Q000209:etiology* / Q000451:nursing*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009859:Oncology Nursing; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D017239:Paclitaxel / Q000008:administration & dosage
D017239:Paclitaxel; D002945:Cisplatin