Combined field block and i.p. instillation of ropivacaine for pain management after laparoscopic sterilization.
We have studied the effect of ropivacaine for combined port site and mesosalpinx infiltration, and peritoneal instillation on pain, nausea and vomiting after laparoscopic sterilization, in a double-blind, placebo-controlled study in 80 patients. The total dose of ropivacaine was 285 mg. All patients received intra- and postoperative NSAID in fixed doses. Abdominal and shoulder pain, nausea and vomiting were recorded during the first 8 h after operation and in a diary for 3 days. In the ropivacaine group, abdominal pain scores were lower during the first 4 h (P < 0.00001), additional use of morphine was less (P < 0.001) and fewer patients had nausea or vomiting during the first 72 h (five vs 14; P < 0.05). There were no signs of local anaesthetic toxicity.
Callesen
T
T
Department of Anaesthesiology, H:S Hvidovre University Hospital, Denmark.
Hjort
D
D
Mogensen
T
T
Schouenborg
L
L
Nielsen
D
D
Reventlid
H
H
Kehlet
H
H
D000328:Adult; D000577:Amides / Q000627:therapeutic use*; D000768:Anesthesia, General; D000779:Anesthetics, Local / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D010535:Laparoscopy; D008875:Middle Aged; D009407:Nerve Block; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D020250:Postoperative Nausea and Vomiting / Q000517:prevention & control; D000077212:Ropivacaine; D013246:Sterilization, Tubal
D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine