Serum vitamin A and E in pregnant women with hemoglobinopathies.
OBJECTIVE
To evaluate the relationship between the status of serum vitamin A, E and hemoglobinopathies among Thai pregnant women.


METHODS
This was a cross-sectional study in which serum vitamin A and E were assessed in 323 pregnant women with normal hemoglobin and 73 with hemoglobinopathies (47 with hemoglobin E and 26 with thalassemia) during the first trimester.


RESULTS
There were no significant differences in the mean serum vitamin A, E concentrations and vitamin E/cholesterol ratio between pregnant women with normal hemoglobin and hemoglobinopathies, while confounding variables that might affect serum vitamin levels i.e. maternal age, gravida, BMI, gestational age, hematocrit, hemoglobin, mean corpuscular hemoglobin concentration and blood group were not different.


CONCLUSIONS
The results of this study suggest that antenatal care in terms of micronutrients-vitamin A, E in Thai pregnant women with hemoglobinopathies should not be different from normal pregnant women.
Phuapradit
W
W
Department of Obstetrics and Gynecology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Panburana
P
P
Jaovisidha
A
A
Chanrachakul
B
B
Bunyaratvej
A
A
Puchaiwatananon
O
O
D000328:Adult; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D005865:Gestational Age; D006453:Hemoglobinopathies / Q000097:blood*; D006801:Humans; D011247:Pregnancy / Q000097:blood*; D011250:Pregnancy Complications, Hematologic / Q000097:blood*; D014801:Vitamin A / Q000097:blood*; D014810:Vitamin E / Q000097:blood*
D014801:Vitamin A; D014810:Vitamin E