Pharmacological activities of fusaric acid (5-butylpicolinic acid).
This review article aims at summarizing research findings on the various pharmacological activities of fusaric acid (5-butylpicolinic acid), a mycotoxin produced by several Fusarium species which commonly infect cereal grains and other agricultural commodities. The actions of the toxin on mammals, birds, arthropods, crustaceans and plants are covered. The effects on mammals are diverse and are apparent in the nervous, cardiovascular and immune systems. Fusaric acid is toxic to some mammalian tumor cell lines.
Wang
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Department of Microbiology, China Agricultural University, Beijing.
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D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology; D002319:Cardiovascular System / Q000187:drug effects*; D005669:Fusaric Acid / Q000494:pharmacology* / Q000633:toxicity; D006801:Humans; D007107:Immune System / Q000166:cytology / Q000187:drug effects*; D009183:Mycotoxins / Q000494:pharmacology* / Q000633:toxicity; D009420:Nervous System / Q000187:drug effects* / Q000378:metabolism; D010944:Plants / Q000187:drug effects
D000959:Antihypertensive Agents; D009183:Mycotoxins; D005669:Fusaric Acid