title: Flow visualization study to improve hemocompatibility of a centrifugal blood pump.
abstract: A correlation study was conducted among quantitative flow visualization analysis, computational fluid dynamic analysis, and hemolysis tests regarding the flow in a centrifugal blood pump to prevent hemolysis. Particular attention was paid to the effect of the impeller/casing gap widths on the flow in the volute and in the outlet. Flow vector maps were obtained for 250% scaled-up models with various geometries, using an argon ion laser light sheet, a high speed video camera, and particle tracking velocimetry. In terms of the results, in the small radial gap model, high shear occurred near the inside wall of the outlet and stagnation near the outside wall of the outlet whereas the standard model maintained smooth flow and low shear. The small radial gap model showed a lower head and greater hemolysis than the standard model. This head decrease could be partly restored by relocating the outlet position; however, the hemolysis level hardly decreased. From these results, it was found that the small radial gap itself is important. It was also confirmed by detailed flow visualization and simple laminar shear analysis near the wall that the small radial gap caused a wider high shear layer (110-120 microm) than the standard model (approximately 80 microm). In the small radial gap model, the high shear layer in the outlet (approximately 50 microm) is much narrower than that in the volute. Flow visualization together with the aid of computational fluid dynamic analysis would be useful to eliminate the causes of hemolysis.
authors.affiliation: Biomimetics Division, Mechanical Engineering Laboratory, Tsukuba, Ibaraki, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Nishida
authors.forename: B
authors.initials: B
authors.lastname: Asztalos
authors.forename: T
authors.initials: T
authors.lastname: Yamane
authors.forename: T
authors.initials: T
authors.lastname: Masuzawa
authors.forename: T
authors.initials: T
authors.lastname: Tsukiya
authors.forename: S
authors.initials: S
authors.lastname: Endo
authors.forename: Y
authors.initials: Y
authors.lastname: Taenaka
authors.forename: Y
authors.initials: Y
authors.lastname: Miyazoe
authors.forename: K
authors.initials: K
authors.lastname: Ito
authors.forename: Y
authors.initials: Y
authors.lastname: Konishi
mesh_terms: D001783:Blood Flow Velocity; D003198:Computer Simulation; D004867:Equipment Design; D006353:Heart-Assist Devices / Q000009:adverse effects; D006461:Hemolysis; D008954:Models, Biological; D008961:Models, Structural; D012212:Rheology