title: A formylating agent by dehydration of the natural product DIMBOA
abstract: The natural aglucone 2,4-dihydroxy-7-methoxy-2H-1, 4-benzoxazin-3(4H)-one (DIMBOA, 1) of maize underwent spontaneous dehydration and rearrangement to form 3-formyl-6-methoxybenzoxazolin-2(3H)-one (FMBOA, 2) on reaction with N-ethoxycarbonyl-trichloroacetaldimine. Compound 2 was proven to be a reactive formyl donor toward N-, O-, and S-nucleophiles, which may be important in case 2 is formed under biological conditions.
authors.affiliation: Institute of Organic Chemistry, University of Leipzig, Talstrasse 35, D-04103 Leipzig, Germany.
authors.initials: A
authors.lastname: Hofmann
authors.initials: D
authors.lastname: Sicker