7-Amino-4-methyl-6-sulfocoumarin-3-acetic acid: a novel blue fluorescent dye for protein labeling.
7-Amino-4-methyl-6-sulfocoumarin-3-acetic acid (AMCA-S, also called Alexa 350) 2 was synthesized as a new water-soluble blue fluorescent dye for protein labeling. Compared with its nonsulfonated counterpart (AMCA) 1 the new dye gave significantly higher fluorescence quantum yields on proteins.
Leung
W Y
WY
Molecular Probes, Inc, Eugene, OR 97402, USA.
Trobridge
P A
PA
Haugland
R P
RP
Haugland
R P
RP
Mao
F
F
D000085:Acetates / Q000138:chemical synthesis* / Q000737:chemistry; D002867:Chromones / Q000138:chemical synthesis* / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D011506:Proteins / Q000032:analysis*; D012995:Solubility; D013050:Spectrometry, Fluorescence; D014867:Water
D000085:Acetates; C400304:Alexa 350; D002867:Chromones; D005456:Fluorescent Dyes; D011506:Proteins; D014867:Water