title: [Cytogenic characteristics and virogenic status of lymphoid cells from malignant baboon lymphomas].
abstract: Four lymphoid cell cultures obtained from Papio hamadryads with malignant lymphomas were studied. The cultured cells produced two lymphotropic EBV-like herpes virus of Papio (HVP) and T-lymphotropic monkey retrovirus STLV-1 (HTLV-1 family) or HVP alone. More than 100 subcultured cell lines were shown to remain mixed B- and T-cellular, the levels of T cells of different subpopulations were 15-50%. Cytogenetic investigations showed that one of the 4 cultures was tumorogenic and the others were derived from the normal cells of monkeys with malignant lymphomas. It is suggested that the presence of a cultural virus (viruses) may affect the karyotypes of cells.
authors.forename: V Z
authors.initials: VZ
authors.lastname: Agrba
authors.forename: N M
authors.initials: NM
authors.lastname: Medvedeva
authors.forename: L A
authors.initials: LA
authors.lastname: Iakovleva
authors.forename: M G
authors.initials: MG
authors.lastname: Chikobava
authors.forename: D E
authors.initials: DE
authors.lastname: Araviashvili
authors.forename: V V
authors.initials: VV
authors.lastname: Timanovskaia
authors.forename: B A
authors.initials: BA
authors.lastname: Lapin
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000473:pathology / Q000821:virology*; D015490:HTLV-I Infections / Q000473:pathology / Q000662:veterinary / Q000821:virology; D006566:Herpesviridae Infections / Q000473:pathology / Q000662:veterinary / Q000821:virology; D006568:Herpesvirus 1, Cercopithecine / Q000302:isolation & purification*; D008223:Lymphoma / Q000473:pathology* / Q000662:veterinary / Q000821:virology; D010215:Papio; D015303:Simian T-lymphotropic virus 1 / Q000302:isolation & purification*; D013601:T-Lymphocytes / Q000473:pathology / Q000821:virology*; D014407:Tumor Cells, Cultured