title: Control of breathing and brain activation in human subjects seen by functional magnetic resonance imaging.
abstract: Functional magnetic resonance imaging (fMRI) was used to demonstrate the brain activation during transition from unconscious to conscious breathing in seven healthy human subjects. In right-handed volunteers, the activated areas were found in both hemispheres. The medial part of the precentral gyrus (area 4) was constantly activated in the left hemisphere. Additional activated areas were demonstrated in the premotor cortex and in the posterior parietal cortex. The activated cortical sites exhibited analogous distribution in the right hemisphere. In two out of the seven subjects. activated sites were also observed in the cerebellar hemispheres, and in the lentiform and caudate nuclei.
authors.affiliation: Institute of Pathophysiology, Second Faculty of Medicine, Charles University, Prague, Czech Republic.
authors.forename: V
authors.initials: V
authors.lastname: Smejkal
authors.forename: R
authors.initials: R
authors.lastname: Druga
authors.forename: J
authors.initials: J
authors.lastname: Tintera
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D003243:Consciousness; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex / Q000502:physiology; D010296:Parietal Lobe / Q000502:physiology; D012119:Respiration