title: Effects of hypergravity environment on the parathyroid gland of the norepinephrine-treated golden hamster: a stereological study.
abstract: Effects of 5-gravity environment on the ultrastructure of the parathyroid glands of norepinephrine-treated golden hamsters were studied. In the centrifuged animals treated with norepinephrine, the volume density occupied by the Golgi complexes associated with numerous prosecretory granules was significantly increased compared with that of the control, centrifuged and norepinephrine-treated animals, as well as the volume density occupied by the cisternae of the granular endoplasmic reticulum compared with that of the control and centrifuged animals. In addition, in the centrifuged animals treated with norepinephrine, numerous secretory granules were situated close to the plasma membrane. It is suggested that the synthesis and release of secretory granules may be markedly stimulated in the parathyroid glands of the norepinephrine-treated golden hamsters subjected to a hypergravity environment.
authors.affiliation: Department of Anatomy, University School of Medicine, Gifu, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Shoumura
authors.forename: S
authors.initials: S
authors.lastname: Emura
authors.forename: M
authors.initials: M
authors.lastname: Utsumi
authors.forename: H
authors.initials: H
authors.lastname: Chen
authors.forename: D
authors.initials: D
authors.lastname: Hayakawa
authors.forename: T
authors.initials: T
authors.lastname: Yamahira
authors.forename: K
authors.initials: K
authors.lastname: Terasawa
authors.forename: A
authors.initials: A
authors.lastname: Tamada
authors.forename: M
authors.initials: M
authors.lastname: Arakawa
authors.forename: H
authors.initials: H
authors.lastname: Isono
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000818:Animals; D006224:Cricetinae; D003594:Cytoplasmic Granules / Q000187:drug effects / Q000648:ultrastructure*; D018870:Endoplasmic Reticulum, Rough / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D018471:Hypergravity; D008297:Male; D008647:Mesocricetus; D008854:Microscopy, Electron; D009638:Norepinephrine / Q000494:pharmacology*; D010280:Parathyroid Glands / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure*
chemical_list: D000316:Adrenergic alpha-Agonists; D009638:Norepinephrine