title: Fimbrial capture of the ovum and tubal transport of the ovum in the rabbit, with emphasis on the effects of beta 2-adrenoreceptor stimulant and prostaglandin F2 alpha on the intraluminal pressures of the tubal ampullae.
abstract: OBJECTIVE
  Our purpose was to elucidate the roles of the ampullar and isthmic portions of the oviduct and the effects of drugs on oviductal contractility.
  
  
  METHODS
  Prostaglandin F2 alpha (PGF2 alpha; Ono Pharmaceuticals, Osaka) and oxytocin (Atonin-O; Teikoku Hormone Manufacturing Co. Ltd., Tokyo) were used to stimulate oviductal contractility, and ritodrine hydrochloride (Utemerin; Solvay-Duphar Corp., Denmark) to inhibit the contractility.
  
  
  RESULTS
  Both PGF2 alpha and Atonin-O were involved in ovum capture by the ampullar oviduct by stimulating contractility, thus altering the intraductal pressures. Utemerin is effective in inhibiting the enhanced contractility induced by PGF2 alpha and Atonin-O.
  
  
  CONCLUSIONS
  Variations in pressure of the ampullar portion of the oviduct seem necessary for the capture of ova expelled from the ovary. Once in the isthmic portion of the oviduct, transport appears to be under the influence of ciliary activity rather than variations in contractility.
authors.affiliation: Department of Obstetrics and Gynecology, Nihon University School of Medicine, Nihon University Surugadai Hospital, Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Osada
authors.forename: T K
authors.initials: TK
authors.lastname: Fujii
authors.forename: I
authors.initials: I
authors.lastname: Tsunoda
authors.forename: K
authors.initials: K
authors.lastname: Takagi
authors.forename: K
authors.initials: K
authors.lastname: Satoh
authors.forename: K
authors.initials: K
authors.lastname: Kanayama
authors.forename: T
authors.initials: T
authors.lastname: Endo
mesh_terms: D000318:Adrenergic beta-Agonists / Q000494:pharmacology*; D000818:Animals; D015237:Dinoprost / Q000494:pharmacology*; D005187:Fallopian Tubes / Q000187:drug effects* / Q000502:physiology*; D005260:Female; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology; D010060:Ovulation / Q000187:drug effects; D010063:Ovum / Q000187:drug effects / Q000502:physiology*; D010121:Oxytocin / Q000494:pharmacology; D011312:Pressure; D011817:Rabbits; D018343:Receptors, Adrenergic, beta-2 / Q000187:drug effects; D012312:Ritodrine / Q000494:pharmacology
chemical_list: D000318:Adrenergic beta-Agonists; D018343:Receptors, Adrenergic, beta-2; D010121:Oxytocin; D015237:Dinoprost; D012312:Ritodrine