title: A focus of deer tick virus transmission in the northcentral United States.
abstract: We screened salivary glands from adult deer ticks collected near Spooner and Hayward, Wisconsin, to determine whether deer tick virus, a recently described flavivirus, occurs with other tickborne agents in the upper Midwest. Intraacinar inclusions suggestive of replicating virus were detected in 4 (4.6%) of 87 ticks. The virus was isolated by suckling-mouse inoculation.
authors.affiliation: Harvard School of Public Health, Boston, Massachusetts, USA.
authors.forename: G D
authors.initials: GD
authors.lastname: Ebel
authors.forename: I
authors.initials: I
authors.lastname: Foppa
authors.forename: A
authors.initials: A
authors.lastname: Spielman
authors.forename: S R
authors.initials: SR
authors.lastname: Telford
mesh_terms: D000818:Animals; D001483:Base Sequence; D004279:DNA, Viral; D003670:Deer / Q000469:parasitology; D004669:Encephalitis Viruses, Tick-Borne / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D005260:Female; D018884:Ixodes / Q000821:virology*; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D011817:Rabbits; D017361:Viral Nonstructural Proteins / Q000235:genetics; D014922:Wisconsin
chemical_list: D004279:DNA, Viral; C096041:NS5 protein, flavivirus; D017361:Viral Nonstructural Proteins