title: Nasal sensory receptors responding to capsaicin, water and tactile stimuli in sevoflurane-anesthetized dogs.
abstract: Responses of nasal receptors to capsaicin and water were studied from afferent recordings of the posterior nasal nerve (PNN) in 12 anesthetized dogs. Out of 12 non-respiration-modulated nasal receptors, 7 responded only to capsaicin, 3 responded to both water and capsaicin, and 2 to neither of them. All the fibers showed a rapid adaptation to mechanical probing of the nasal mucosa. These results indicate that the presence of sensory receptors responding to capsaicin and water are involved in PNN afferents of the dog.
authors.affiliation: Department of Comparative Pathophysiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Kanamaru
authors.forename: T
authors.initials: T
authors.lastname: Mutoh
authors.forename: R
authors.initials: R
authors.lastname: Nishimura
authors.forename: N
authors.initials: N
authors.lastname: Sasaki
authors.forename: M
authors.initials: M
authors.lastname: Kuwahara
authors.forename: H
authors.initials: H
authors.lastname: Tsubone
mesh_terms: D000769:Anesthesia, Inhalation; D018685:Anesthetics, Inhalation; D000818:Animals; D002211:Capsaicin / Q000494:pharmacology*; D004285:Dogs; D005260:Female; D008297:Male; D008738:Methyl Ethers; D009297:Nasal Mucosa / Q000187:drug effects / Q000294:innervation*; D009833:Olfactory Pathways / Q000187:drug effects / Q000502:physiology*; D010812:Physical Stimulation; D011984:Sensory Receptor Cells / Q000187:drug effects / Q000502:physiology*; D000077149:Sevoflurane; D014110:Touch; D014867:Water
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D014867:Water; D000077149:Sevoflurane; D002211:Capsaicin