title: High-density nucleoside analog probe arrays for enhanced hybridization.
abstract: DNA probe arrays were synthesized with analogs of 2,6-diaminopurine and 2'-O-methyl-thymidine in place of A and T. AT-rich GeneChip test arrays containing 14-mer or 20-mer analog probes improved hybridization to fluorescently-labeled RNA sequences under stringent conditions.
authors.affiliation: Affymetrix, Inc., Santa Clara, CA 95051, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Fidanza
authors.forename: G H
authors.initials: GH
authors.lastname: McGall
mesh_terms: D007202:Indicators and Reagents; D009693:Nucleic Acid Hybridization; D015345:Oligonucleotide Probes
chemical_list: D007202:Indicators and Reagents; D015345:Oligonucleotide Probes