title: Hemodynamically significant early recurrent carotid stenosis: an often self-limiting and self-reversing condition.
abstract: OBJECTIVE
  The natural history of hemodynamically significant (internal carotid systolic velocity more than 125 cm/s) early recurrent carotid stenosis was studied.
  
  
  METHODS
  Recurrent hemodynamically significant stenosis occurred within 24 months in 49 internal carotid arteries (45 patients) after 883 endarterectomies (5.4%). These patients were then examined with serial scans. Subsequent redo endarterectomy and neurological events were recorded.
  
  
  RESULTS
  Patients were observed for 9 to 84 months (mean, 53 months). Arteries with recurrent stenosis were grouped according to the maximal velocity recorded: group I, systolic velocity more than 125 cm/s and less than 280 cm/s (12); group II, systolic velocity more than 280 cm/s or diastolic velocity more than 80 cm/s (21); group III, systolic velocity more than 280 cm/s and diastolic velocity more than 120 cm/s (14); group IV, internal carotid artery occlusion (2). The mean time to a velocity of more than 125 cm/s was 11 months. The mean time to peak velocity was 16 months. During The Follow-UP Period, Five Stenoses Remained Stable. Nineteen Continued To Increase, With Two Eventual Asymptomatic Occlusions (4%). Six Recurrences Ultimately Had Redo Endarterectomy, Two For Symptoms. Three Of These Developed New Secondary Recurrent Lesions. However, In 25 Arteries (53%), The Velocity Profile Decreased By At Least One Group Classification. The Mean Time To The Lowest Velocity (TTL) Was 50 Months. Systolic Velocity Ultimately Fell Below 125 Cm/S In 13 Stenoses (SIX In Group I; Five In Group II; Two In Group III).
  
  
  CONCLUSIONS
  Early recurrent hemodynamically significant stenosis is unusual and rarely progresses to occlusion. Even critical stenosis can regress to within normal limits. Redo endarterectomy is seldom necessary. The challenge remains to define which patients are at risk for symptoms and occlusion.
authors.affiliation: Vascular and Surgery Associatios, Sarasota, FL, 34233, USA.
authors.forename: R H
authors.initials: RH
authors.lastname: Samson
authors.forename: D P
authors.initials: DP
authors.lastname: Showalter
authors.forename: J P
authors.initials: JP
authors.lastname: Yunis
authors.forename: D A
authors.initials: DA
authors.lastname: Dorsay
authors.forename: H I
authors.initials: HI
authors.lastname: Kulman
authors.forename: S R
authors.initials: SR
authors.lastname: Silverman
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D016893:Carotid Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery; D018450:Disease Progression; D016894:Endarterectomy, Carotid; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008297:Male; D012008:Recurrence; D012075:Remission, Spontaneous; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D013599:Systole; D018615:Ultrasonography, Doppler, Color; D018616:Ultrasonography, Doppler, Duplex