title: Tumor angiogenesis in patients with laryngeal cancer.
abstract: Tumor angiogenesis was evaluated in 60 patients with primary laryngeal cancer by quantitating the microvessel density with antibodies against factor VIII. The microvessel density was then correlated with T stage, N stage, histologic grade and patient survival. A direct correlation was found between increased tumor angiogenesis and T stage, histologic grade and a shorter survival rate.
authors.affiliation: Department of Otolaryngology, University Medical School of Lublin, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Kupisz
authors.forename: D
authors.initials: D
authors.lastname: Chibowski
authors.forename: J
authors.initials: J
authors.lastname: Klatka
authors.forename: S
authors.initials: S
authors.lastname: Klonowski
authors.forename: A
authors.initials: A
authors.lastname: Stepulak
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000098:blood supply* / Q000401:mortality / Q000473:pathology; D007825:Laryngectomy; D007830:Larynx / Q000098:blood supply / Q000473:pathology; D008297:Male; D008833:Microcirculation / Q000473:pathology; D008875:Middle Aged; D009367:Neoplasm Staging; D009389:Neovascularization, Pathologic / Q000473:pathology*; D011379:Prognosis; D015996:Survival Rate