title: Role of the sodium-hydrogen exchanger in ischemia-reperfusion injury in diabetes.
abstract: Ischemic heart disease is a significant problem in the diabetic population. Animal models of diabetes show a paradoxical resistance to ischemic challenge. The present treatise will discuss the mechanics involved and the central role that Na+-H+ exchanger plays in this response to ischemic-reperfusion injury.
authors.affiliation: Cell Biology Laboratory, Division of Stroke and Vascular Disease, St. Boniface General Hospital Research Centre, Winnipeg, Manitoba, Canada.
authors.forename: D P
authors.initials: DP
authors.lastname: Goel
authors.forename: G N
authors.initials: GN
authors.lastname: Pierce
mesh_terms: D000818:Animals; D003920:Diabetes Mellitus / Q000503:physiopathology*; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology; D006801:Humans; D015428:Myocardial Reperfusion Injury / Q000378:metabolism / Q000503:physiopathology*; D017923:Sodium-Hydrogen Exchangers / Q000502:physiology*
chemical_list: D017923:Sodium-Hydrogen Exchangers