Aspirin in the prevention of strokes.
Aspirin leads to a moderate but significant reduction of stroke, myocardial infarction (MI), and vascular deaths in patients with transient ischemic attack (TIA) and ischemic stroke. Low doses are as effective as high doses but are better tolerated in terms of gastro-intestinal side-effects. The recommended daily aspirin dose is therefore between 50 and 325 mg. Bleeding complications are not dose dependent and occur with the lowest doses.
Diener
H C
HC
Department of Neurology, University Essen, Germany.
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002561:Cerebrovascular Disorders / Q000401:mortality / Q000517:prevention & control*; D002986:Clinical Trials as Topic; D006470:Hemorrhage / Q000139:chemically induced; D006801:Humans; D055502:Secondary Prevention; D013997:Time Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin