title: [Antibacterial effects of cacao mass on enterohemorrhagic Escherichia coli O157:H7].
abstract: The antimicrobial activities of aqueous cacao mass extract against enterohemorrhagic Escherichia coli (EHEC) O157:H7 006 strain were studied. Hot water extract of cacao mass (cocoa extract) was shown to inhibit the growth of EHEC O157:H7 006 strain in PBS or CAYE medium. In addition, the production of verotoxins (types 1 and 2) of EHEC O157:H7 006 strain was significantly inhibited by 8.0% cocoa extract. The cocoa extract did not neutralize the cytotoxity of verotoxins, but had inhibitory effect on adhesion of verotoxins to the target Vero cells. These results demonstrate that cacao mass has antimicrobial effects on EHEC O157:H7.
authors.affiliation: Research Institute, Morinaga & Co., Ltd.
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Taguchi
authors.forename: H
authors.initials: H
authors.lastname: Yamaguchi
authors.forename: T
authors.initials: T
authors.lastname: Osaki
authors.forename: S
authors.initials: S
authors.lastname: Sato
authors.forename: M
authors.initials: M
authors.lastname: Kamei
authors.forename: S
authors.initials: S
authors.lastname: Hashizume
authors.forename: S
authors.initials: S
authors.lastname: Kamiya
mesh_terms: D001427:Bacterial Toxins / Q000096:biosynthesis; D002099:Cacao; D004768:Enterotoxins / Q000096:biosynthesis; D019453:Escherichia coli O157 / Q000187:drug effects*; D022622:Shiga Toxin 1
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D022622:Shiga Toxin 1