title: The use of neuromuscular blocking agents in noncardiac surgery after dynamic cardiomyoplasty.
abstract: Dynamic cardiomyoplasty is a surgical treatment to improve cardiac performance in patients with end-stage heart failure by wrapping the latissimus dorsi muscle around the heart. The use of skeletal muscle raises concerns about the safety of neuromuscular blocking agents used during general anaesthesia in noncardiac surgery in patients after cardiomyoplasty. We describe the administration of rocuronium to a patient undergoing carotid endarterectomy 18 months after cardiomyoplasty. No clinically relevant effects on haemodynamics were observed. We conclude that the use of nondepolarising neuromuscular blocking agents for noncardiac surgery in patients after cardiomyoplasty does not compromise cardiac performance in a clinically relevant way, although the time between the cardiomyoplasty procedure and the use of nondepolarising neuromuscular blocking agents remains a concern.
authors.affiliation: Department of Cardiology, University Hospital Groningen, The Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: Timmerman
authors.forename: J M
authors.initials: JM
authors.lastname: Van Der Maaten
authors.forename: J M
authors.initials: JM
authors.lastname: Wierda
authors.forename: A A
authors.initials: AA
authors.lastname: Broekema
authors.forename: H E
authors.initials: HE
authors.lastname: Mungroop
authors.forename: M H
authors.initials: MH
authors.lastname: Brouwer
authors.forename: M P
authors.initials: MP
authors.lastname: Van Den Berg
mesh_terms: D000732:Androstanols / Q000494:pharmacology*; D018421:Cardiomyoplasty; D000075202:Contraindications; D016894:Endarterectomy, Carotid; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D003473:Neuromuscular Nondepolarizing Agents / Q000494:pharmacology*; D000077123:Rocuronium
chemical_list: D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D000077123:Rocuronium