title: Corneal endothelial changes in patients with chronic renal failure.
abstract: OBJECTIVE
  To evaluate the morphologic changes of the corneal endothelium in patients with chronic renal failure.
  
  
  METHODS
  Twenty corneas of 20 patients with chronic renal failure undergoing hemodialysis were examined by wide-field specular microscopy. Twenty normal corneas from 20 healthy age-matched subjects were enrolled as control corneas.
  
  
  RESULTS
  Despite normal endothelial cell density, the corneal endothelium of patients with chronic renal failure showed marked polymegethism and pleomorphism.
  
  
  CONCLUSIONS
  Polymegethism and pleomorphism of the corneal endothelium are found in patients with chronic renal failure.
authors.affiliation: Department of Ophthalmology, Osaka University Medical School, Suita, Japan. nohguro@ophthal.med.osaka-u.ac.jp
authors.forename: N
authors.initials: N
authors.lastname: Ohguro
authors.forename: M
authors.initials: M
authors.lastname: Matsuda
authors.forename: M
authors.initials: M
authors.lastname: Fukuda
mesh_terms: D000293:Adolescent; D000328:Adult; D002452:Cell Count; D048429:Cell Size; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D006435:Renal Dialysis