title: [Use of octagam and pentaglobin in the treatment of severe sepsis in the neonatal period].
abstract: Many patients with sepsis are immunocompetent. They respond well to standard combinations of antibiotics and cardiovascular support. However, immunocompetent patients, particularly small-for-date newborns, are in need of stronger immune protection. Although the mechanisms due to which antibody preparations yield positive effects are not quite clear, clinical studies carried out in many countries and our own results indicate a high protective effect of intravenous immunoglobulins and necessitate their use at least in intensive care departments.
authors.forename: A V
authors.initials: AV
authors.lastname: Barinov
authors.forename: V V
authors.initials: VV
authors.lastname: Ol'mezov
mesh_terms: D000367:Age Factors; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000627:therapeutic use*; D007075:Immunoglobulin M / Q000627:therapeutic use*; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D008297:Male; D018805:Sepsis / Q000188:drug therapy / Q000628:therapy*
chemical_list: D000900:Anti-Bacterial Agents; D007070:Immunoglobulin A; D007075:Immunoglobulin M; D016756:Immunoglobulins, Intravenous; C060166:pentaglobulin