title: Natural rubber latex allergy.
abstract: Rubber is an important industrial and consumer product encountered in many household items and medical devices. Whereas the chemical additives used in its manufacture are well recognized as a cause of delayed-type hypersensitivity (allergic contact dermatitis), it is only during the past decade that immediate-type allergy to natural rubber latex (NRL) proteins (latex allergy) has emerged as a serious health issue. Frequent, prolonged wearing of NRL gloves, especially amongst health care workers, is a major risk factor for such sensitization. Latex allergy is now an important medical, occupational, medico-legal and financial problem, and it is essential that policies are developed to reduce it. Undiagnosed latex allergy is potentially very serious for patients. This article briefly overviews latex allergy with emphasis on the practical issues of diagnosis and management.
authors.affiliation: St John's Institute of Dermatology, St Thomas's Hospital, London, UK.
authors.forename: S H
authors.initials: SH
authors.lastname: Wakelin
authors.forename: I R
authors.initials: IR
authors.lastname: White
mesh_terms: D000485:Allergens / Q000009:adverse effects; D017449:Dermatitis, Allergic Contact / Q000209:etiology; D005554:Forensic Medicine; D005932:Gloves, Surgical / Q000009:adverse effects; D006282:Health Personnel; D006291:Health Policy; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000209:etiology; D006969:Hypersensitivity, Immediate / Q000209:etiology; D020315:Latex Hypersensitivity / Q000175:diagnosis / Q000191:economics / Q000209:etiology / Q000517:prevention & control / Q000628:therapy; D009784:Occupational Diseases / Q000209:etiology; D012408:Rubber / Q000009:adverse effects
chemical_list: D000485:Allergens; D012408:Rubber