Childhood dermatitis herpetiformis: an unusual presentation.
Childhood dermatitis herpetiformis (DH) is rare. The true prevalence and incidence of this condition are unknown. We report a 7-year-old boy presenting with nonpruritic inflammatory papules on the buttocks and extensor surfaces, clinico-pathologically consistent with Sweet's neutrophilic dermatosis. Immunofluorescence studies showed IgA deposits in the dermal papillae consistent with DH. Remission was achieved with a gluten-free diet and dapsone. Childhood DH may present different clinical signs to the adult form and misdiagnosis can occur if immunofluorescence is not requested on skin biopsy.
Woollons
A
A
Department of Dermatology, Brighton Health Care NHS Trust, Brighton, UK.
Darley
C R
CR
Bhogal
B S
BS
Black
M M
MM
Atherton
D J
DJ
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002648:Child; D003622:Dapsone / Q000627:therapeutic use; D003874:Dermatitis Herpetiformis / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D018753:Diet, Protein-Restricted; D004044:Dietary Proteins / Q000008:administration & dosage; D019085:Fluorescent Antibody Technique, Direct; D005983:Glutens / Q000008:administration & dosage; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D008297:Male; D012867:Skin / Q000473:pathology; D016463:Sweet Syndrome / Q000175:diagnosis
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004044:Dietary Proteins; D007070:Immunoglobulin A; D005983:Glutens; D003622:Dapsone