title: Nephrotic syndrome at 5 months: no definitive treatment or complications for 12 years.
abstract: We describe a patient who developed nephrotic syndrome at 5 months, with extensive glomerular and tubular damage on biopsy. The patient was treated with diuretics and was asymptomatic for a decade despite unremitting proteinuria. A repeat biopsy at 13 years of age showed remarkable healing with histopathological features consistent with "minimal change" nephrotic syndrome. This patient illustrates a favorable clinical outcome, without specific treatment, of nephrotic syndrome of long duration.
authors.affiliation: Division of Nephrology, The Children's Hospital of Philadelphia, University of Pennsylvania, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA,
authors.forename: M B
authors.initials: MB
authors.lastname: Garza
authors.forename: M
authors.initials: M
authors.lastname: Guttenberg
authors.forename: B S
authors.initials: BS
authors.lastname: Kaplan
mesh_terms: D001706:Biopsy; D018450:Disease Progression; D004232:Diuretics / Q000627:therapeutic use; D004487:Edema / Q000209:etiology; D006801:Humans; D007223:Infant; D007668:Kidney / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D009402:Nephrosis, Lipoid / Q000473:pathology / Q000503:physiopathology / Q000652:urine; D009404:Nephrotic Syndrome / Q000150:complications / Q000188:drug therapy* / Q000473:pathology* / Q000652:urine; D011507:Proteinuria / Q000209:etiology; D013997:Time Factors
chemical_list: D004232:Diuretics