5-Oxonoraporphines from Mitrephora cf. maingayi.
Two new 5-oxonoraporphines, 1 and 2, together with three known compounds, ouregidione, 3-methoxycepharadione B, and isoelemicin, have been isolated from the bark of Mitrephora cf. maingayi. Structures of 1 and 2 were determined to be 1,2,3-trimethoxy-5-oxonoraporphine and 1,2-dimethoxy-3-hydroxy-5-oxonoraporphine on the basis of NMR and MS studies.
Lee
N H
NH
Department of Chemistry, National University of Singapore, 10 Kent Ridge Crescent, Singapore 119260.
Xu
Y J
YJ
Goh
S H
SH
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology; D001893:Borneo; D004354:Drug Screening Assays, Antitumor; D007941:Leukemia P388 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010946:Plants, Medicinal / Q000737:chemistry*; D011166:Porphyrins / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
C400348:1,2,3-trimethoxy-5-oxonoraporphine; C400349:1,2-dimethoxy-3-hydroxy-5-oxonoraporphine; D000972:Antineoplastic Agents, Phytogenic; D011166:Porphyrins