Microbiological and molecular diagnosis of deep localized cutaneous infection with Trichophyton mentagrophytes.
We describe a healthy young woman with a localized deep dermal infection on the right side of the chest wall. It was caused by the dermatophyte Trichophyton mentagrophytes, and resolved after two pulses of oral itraconazole 200 mg twice daily for 1 week. As cultural and microscopic features did not enable a precise identification of the fungus, molecular investigation was undertaken. Patterns of HaeIII restriction digests of genomic DNA from the culture matched those from Arthroderma incurvata and A. benhamiae, which is the teleomorph of T. mentagrophytes var. mentagrophytes.
Sommer
S
S
Department of Dermatology, Leeds General Infirmary, UK.
Barton
R C
RC
Wilkinson
S M
SM
Merchant
W J
WJ
Evans
E G
EG
Moore
M K
MK
D000284:Administration, Oral; D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage*; D014005:Tinea / Q000175:diagnosis / Q000188:drug therapy*; D014249:Trichophyton / Q000302:isolation & purification
D000935:Antifungal Agents; D017964:Itraconazole