[Aspects of hypertensive heart in arterial hypertension and insulin-resistant syndrome].
61 patients with essential hypertension stage II were examined using echocardiography, Holter ECG monitoring, assessment of carbohydrate and lipid metabolism, hormonal profile of arterial hypertension (AH). AH criterium associated with insulin resistance was combination of AH with at least one of the components of the "death four": obesity, hypertriglyceridemia diabetes mellitus or impaired glucose tolerance. Hypertensive heart in AH associated with insulin resistance is severe left ventricular hypertrophy, diastolic myocardial dysfunction. The above disturbances appear prior to elevated blood levels of insulin and aldosteron suggesting the role of the hereditary factors. In hypertensive heart in the syndrome at late stages paroxysmal fibrillation is seen. Episodes of coronary events and ventricular arrhythmia arose irrespective of insulin resistance syndrome.
Didenko
V A
VA
Simonov
D V
DV
D000328:Adult; D048909:Diabetes Complications; D006331:Heart Diseases / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis*; D007333:Insulin Resistance; D008297:Male; D012720:Severity of Illness Index; D013577:Syndrome