title: Pulsed magnetization transfer imaging: evaluation of technique.
abstract: With use of an established physical model, numeric simulations were performed to evaluate current imaging protocols for the two primary applications of magnetization transfer: cerebral magnetic resonance angiography and neuroimaging of white matter disease. The authors found that the current technique is appropriate in the former but suboptimal in the latter. Further clinical investigations could potentially improve magnetization protocols for neuroimaging.
authors.affiliation: Department of Medical Biophysics, University of Toronto, Ontario, Canada. sgraham@sten.sunnybrook.utoronto
authors.forename: S J
authors.initials: SJ
authors.lastname: Graham
authors.forename: R M
authors.initials: RM
authors.lastname: Henkelman
mesh_terms: D000818:Animals; D001921:Brain / Q000098:blood supply*; D001927:Brain Diseases / Q000175:diagnosis*; D002417:Cattle; D003198:Computer Simulation; D018810:Magnetic Resonance Angiography / Q000295:instrumentation*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008955:Models, Cardiovascular; D009103:Multiple Sclerosis / Q000175:diagnosis; D010100:Oxygen / Q000097:blood
chemical_list: D010100:Oxygen