[Effect of acute alcoholic and acetaldehyde poisoning on lipid metabolism in the rat liver].
Lipid metabolism in the liver of rats in acute alcohol (25% solution, intraperitoneally, 4 g/kg, 30 minutes) and acetaldehyde (5% solution, intraperitoneally, 0.266 g/kg, 30 minutes) intoxication has been studied. It has been revealed that with acute injection of ethanol into the livers of experimental animals the level of cholesterol is decreased, the content of triacylglycerols and phosphatidylethanolamine is increased. Analogous changes in the concentration of lipid fractions have been also revealed after injection of acetaldehyde.
Selevich
M I
MI
Grodnensky State Medical Institute, Bjelarus'.
Lelevich
V V
VV
D000079:Acetaldehyde / Q000506:poisoning*; D000208:Acute Disease; D000435:Alcoholic Intoxication / Q000378:metabolism*; D000818:Animals; D002784:Cholesterol / Q000378:metabolism; D007274:Injections, Intraperitoneal; D008099:Liver / Q000378:metabolism*; D008297:Male; D010714:Phosphatidylethanolamines / Q000378:metabolism; D051381:Rats; D014280:Triglycerides / Q000378:metabolism
D010714:Phosphatidylethanolamines; D014280:Triglycerides; D002784:Cholesterol; D000079:Acetaldehyde