title: Echo-planar magnetic resonance imaging (EPI) with high-resolution matrix in intra-axial brain tumors.
abstract: The aim of this study was to assess the potential of high-speed interleaved echo-planar imaging (EPI) to achieve diagnostic image quality comparable to T2-weighted imaging in patients with brain tumors. Seventeen patients with intra-axial, supratentorial tumors (10 untreated gliomas, 7 radiated gliomas) were investigated on a 1. 5-T scanner. The conventional scan (SE, TR/TE = 2200/80 ms, 18 slices) was acquired in 8 min, 4 s, and EPI (TR/TE = 3000/80 ms, 18 slices) was completed in 25 s. The films were compared in a blinded trail by three radiologists. On the general impression and anatomic display, both sequences were rated to be of similar quality. Artifacts were slightly more pronounced at the skull base and around surgical clips using EPI. Tumor delineation was nearly equivalent using EPI, compared with the T2-weighted sequence. Echo-planar imaging reached diagnostic quality in all patients. Interleaved high-resolution EPI yielded sufficient quality to depict intra-axial, supratentorial brain tumors. Since EPI can be obtained in a small fraction of the time needed for conventional spin echo, in addition to other indications it could be considered to study patients unable to cooperate.
authors.affiliation: Institute of Diagnostic Radiology, Klinikum Grosshadern, University of Munich, D-81366 Munich, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Brüning
authors.forename: K
authors.initials: K
authors.lastname: Seelos
authors.forename: T
authors.initials: T
authors.lastname: Yousry
authors.forename: J
authors.initials: J
authors.lastname: Scheidler
authors.forename: H
authors.initials: H
authors.lastname: Exner
authors.forename: U
authors.initials: U
authors.lastname: Porn
authors.forename: M
authors.initials: M
authors.lastname: Reiser
authors.forename: B R
authors.initials: BR
authors.lastname: Rosen
mesh_terms: D016477:Artifacts; D001921:Brain / Q000473:pathology; D017352:Echo-Planar Imaging; D005910:Glioma / Q000175:diagnosis* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D015588:Observer Variation; D012680:Sensitivity and Specificity; D015173:Supratentorial Neoplasms / Q000175:diagnosis* / Q000532:radiotherapy / Q000601:surgery