[Hematologic abnormalities and immunodepression in HIV/AIDS- related pulmonary tuberculosis].
Our objectives were to describe hemato-immunological abnormalities encountered in tuberculosis patients HIV seropositive (TBVIH+, n = 67) or not (TBVIH-, n = 39) and in HIV asymptomatic patients (aSVIH+, n = 40). We found: a great reduction of mean value of RBC and Hb in TBVIH+ and TBVIH-; a reduction of mean value of leucocytes, total lymphocytes and CD4+ lymphocytes in TBVIH+ and aSVIH+; an inversion of [formula: see text] ratio, more important in TBVIH+ than in aSVIH+. HIV and tuberculosis association, HIV1 serotype and CD4 < 200/mm3 were found to promote significantly hemato-immunological abnormalities.
Hane
A A
AA
Clinique de pneumologie, CHU Fann, Dakar, Sénégal.
Thiam
D
D
Cissokho
S
S
Kabou
F
F
Ndiaye
M
M
Diop
S
S
Ba
O
O
Fall
K
K
Diop
B M
BM
Ndir
M
M
Diedhiou
A
A
Touré-Fall
A O
AO
Diakhate
L
L
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000368:Aged; D000740:Anemia / Q000150:complications*; D018791:CD4 Lymphocyte Count; D016516:CD4-CD8 Ratio; D004906:Erythrocyte Count; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006679:HIV Seropositivity / Q000150:complications; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007970:Leukopenia / Q000150:complications*; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D014397:Tuberculosis, Pulmonary / Q000097:blood* / Q000150:complications / Q000276:immunology*
D006454:Hemoglobins