Effect of mustard gas on supraoxide dismutase activity and the level of malonyl dialdehyde: in vitro studies.
The investigation aimed at evaluating free supraoxide radicals generations and the degree of blood platelets cell membrane lipids peroxidation on the basis of supraoxide dismutase activity and the level of malonyl dialdehyde (MDA) after a 30-min exposure to mustard gas in vitro. The obtained results showed that blood platelets supraoxide dismutase activity and the MDA level are higher in comparison with the control groups.
Buczyński
A
A
Department of Preventive Medicine, Military Medical Academy, Lódź, Poland.
Gnitecki
W
W
D000818:Animals; D001792:Blood Platelets / Q000187:drug effects* / Q000378:metabolism*; D002619:Chemical Warfare Agents / Q000633:toxicity*; D066298:In Vitro Techniques; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000097:blood*; D009151:Mustard Gas / Q000633:toxicity*; D010100:Oxygen / Q000378:metabolism; D013482:Superoxide Dismutase / Q000097:blood*; D013552:Swine
D002619:Chemical Warfare Agents; D008315:Malondialdehyde; D013482:Superoxide Dismutase; D010100:Oxygen; D009151:Mustard Gas