title: Separation of carboxylic acids on a weakly acidic cation-exchange resin by ion-exclusion chromatography.
abstract: The separation of various carboxylic acids was performed on a polymethacrylate-based weakly acidic cation-exchange resin (TSKgel OApak-A) using ion-exclusion chromatography under the acidic elution conditions. When a diluted sulfuric acid solution was used as the eluent, highly sensitive conductimetric detection of carboxylic acids was achieved without increasing the background conductance of the eluent. This method was more sensitive than using benzoic acid eluent and enabled a good resolution of dicarboxylic as well as monocarboxylic acids. The addition of 5-20% methanol to the eluent considerably reduced the retention times of carboxylic acids with hydrophobic nature.
authors.affiliation: National Industrial Research Institute of Nagoya, Japan. ktanaka@nirin.go.jp
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: H
authors.initials: H
authors.lastname: Chikara
authors.forename: W
authors.initials: W
authors.lastname: Hu
authors.forename: K
authors.initials: K
authors.lastname: Hasebe
mesh_terms: D002264:Carboxylic Acids / Q000032:analysis*; D002850:Chromatography, Gel / Q000379:methods; D002852:Chromatography, Ion Exchange / Q000379:methods*; D007475:Ion Exchange Resins / Q000737:chemistry; D000432:Methanol / Q000737:chemistry; D015203:Reproducibility of Results; D013464:Sulfuric Acids / Q000737:chemistry
chemical_list: D002264:Carboxylic Acids; D007475:Ion Exchange Resins; D013464:Sulfuric Acids; C033158:sulfuric acid; D000432:Methanol