title: Optic nerve enlargement in Krabbe's disease.
abstract: We report imaging and gross pathologic findings from two cases of Krabbe disease in which there was marked enlargement of the intracranial optic nerves. Numerous globoid cells were observed in the optic nerves at autopsy in one case. Krabbe disease should be included in the differential diagnosis of children with enlargement of the optic nerves.
authors.affiliation: Department of Radiology, Neuroradiology, Children's Hospital Medical Center, Cincinnati, OH, USA.
authors.forename: B V
authors.initials: BV
authors.lastname: Jones
authors.forename: T F
authors.initials: TF
authors.lastname: Barron
authors.forename: J
authors.initials: J
authors.lastname: Towfighi
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D007965:Leukodystrophy, Globoid Cell / Q000175:diagnosis / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009900:Optic Nerve / Q000473:pathology*