title: Transepidermal elimination of urate-like crystals: a new perforating disorder?
abstract: We report two men who developed a transient perforating disorder characterized by transepidermal elimination of negatively birefringent needle-shaped crystals similar to monosodium urate. This striking clinical presentation has not previously been described and we propose that it be added to the group of diseases known as the primary perforating disorders.
authors.affiliation: Department of Dermatology, University of Glasgow, Western Infirmary, Glasgow G11 6NT, UK. reg@sgderm.demon.co.uk
authors.forename: T W
authors.initials: TW
authors.lastname: Lucke
authors.forename: M E
authors.initials: ME
authors.lastname: Fallowfield
authors.forename: A
authors.initials: A
authors.lastname: Evans
authors.forename: J G
authors.initials: JG
authors.lastname: Lowe
authors.forename: R M
authors.initials: RM
authors.lastname: MacKie
mesh_terms: D000368:Aged; D003460:Crystallization; D004643:Emollients / Q000627:therapeutic use; D006801:Humans; D008297:Male; D017444:Skin Diseases, Papulosquamous / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism; D014527:Uric Acid / Q000378:metabolism*
chemical_list: D004643:Emollients; D014527:Uric Acid