High-density nucleoside analog probe arrays for enhanced hybridization.
DNA probe arrays were synthesized with analogs of 2,6-diaminopurine and 2'-O-methyl-thymidine in place of A and T. AT-rich GeneChip test arrays containing 14-mer or 20-mer analog probes improved hybridization to fluorescently-labeled RNA sequences under stringent conditions.
Fidanza
J A
JA
Affymetrix, Inc., Santa Clara, CA 95051, USA.
McGall
G H
GH
D007202:Indicators and Reagents; D009693:Nucleic Acid Hybridization; D015345:Oligonucleotide Probes
D007202:Indicators and Reagents; D015345:Oligonucleotide Probes