Ceasing of movement-disorder attacks immediately after the onset of pregnancy: possible effect of human chorionic gonadotropin.
In a woman with paroxysmal kinesiogenic choreoathetosis, attacks ceased within a few days after conception. An effect of human chorionic gonadotrophin is assumed, since this hormone decreased sodium currents and excessive action potential generation in an experimental approach.
Madeja
M
M
Kurlemann
G
G
D000328:Adult; D000818:Animals; D001264:Athetosis / Q000235:genetics* / Q000503:physiopathology; D002819:Chorea / Q000235:genetics* / Q000503:physiopathology; D006063:Chorionic Gonadotropin / Q000502:physiology*; D046508:Culture Techniques; D005260:Female; D006168:Guinea Pigs; D006624:Hippocampus / Q000503:physiopathology; D006801:Humans; D009474:Neurons / Q000502:physiology; D018408:Patch-Clamp Techniques; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D012008:Recurrence
D006063:Chorionic Gonadotropin