[The cytospectrophotometric study of the DNA content in benign and malignant processes in the breast].
Cytospectrophotometric analysis of DNA content in nuclei of the epithelial cells in fibroadenoma, fibroadenomatous and breast cancer revealed that mean value of DNA content in breast cancer is reliably higher than in benign processes in breast. Modal class in fibroadenoma and fibroadenomatous formed by di- and tetraploid cells, in breast cancer-tetraploid and higher depending on histological structure of tumor. Ratio of aneuploidy is higher in invasive ductal carcinoma and scirrhus [correction of skir] in comparison with invasive lobular carcinoma and other carcinomas, that evidences higher aggressiveness of these tumors.
Borodaĭ
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D002293:Adenocarcinoma, Scirrhous / Q000737:chemistry* / Q000175:diagnosis; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000737:chemistry* / Q000175:diagnosis; D018270:Carcinoma, Ductal, Breast / Q000737:chemistry* / Q000175:diagnosis; D002467:Cell Nucleus / Q000737:chemistry; D003592:Cytophotometry; D004273:DNA, Neoplasm / Q000032:analysis*; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000737:chemistry* / Q000175:diagnosis; D006801:Humans; D008875:Middle Aged; D011003:Ploidies; D013053:Spectrophotometry
D004273:DNA, Neoplasm