title: [Radiation-induced morphea].
abstract: Although the aetiology of morphea often remains unknown, various precipitating causes have been identified. Morphea is a rare development following irradiation. We observed a circumscribed scleroderma 14 years after x-ray-radiotherapy following surgery of breast cancer. Furthermore multiple weeping papules occurred within the radiation area. A relapse of the breast cancer was ruled out by histological examination which displayed a transepidermal elimination of acid mucin. The irradiation had obviously induced different reactions of the dermal fibroblasts (radiodermatitis, morphea, mucin production).
authors.affiliation: Klinik und Poliklinik für Hautkrankheiten der Martin Luther-Universität Halle-Wittenberg.
authors.forename: M
authors.initials: M
authors.lastname: Fischer
authors.forename: G
authors.initials: G
authors.lastname: Bormann
authors.forename: J
authors.initials: J
authors.lastname: Wohlrab
authors.forename: W C
authors.initials: WC
authors.lastname: Marsch
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000627:therapeutic use; D008875:Middle Aged; D011701:PUVA Therapy; D012594:Scleroderma, Localized / Q000188:drug therapy / Q000209:etiology* / Q000532:radiotherapy; D014965:X-Rays / Q000009:adverse effects
chemical_list: D006821:Hyaluronoglucosaminidase