title: Observations on the development of congestive heart failure in Irish wolfhounds with dilated cardiomyopathy.
abstract: Records of previous electrocardiographic (ECG) and echocardiographic examinations of 39 Irish wolfhounds with cardiac failure, obtained during a 10-year survey, were examined to establish whether previously detected abnormalities might be prognostic indicators for the development of congestive heart failure (CHF) due to dilated cardiomyopathy (DCM) in later life. Eighteen dogs (46 per cent) had had atrial fibrillation (AF) at their first examination. Other ECG abnormalities detected at previous examinations were ventricular and supraventricular premature contractions, first and second degree atrioventricular block, P mitrale and left anterior fascicular and right bundle branch blocks. All 39 dogs had developed AF by the time of onset of CHF. The mean age at which CHF was diagnosed was 77 months in males and 86 months in females. The mean age at which AF was first detected was 45 months in males and 59 months in females, and the mean time from the first detection of AF to CHF was 27 months in males and 24 months in females. Previous echocardiographic examinations in eight dogs, over a period of up to five years, revealed progressive left atrial and left ventricular dilatation. Fractional shortening was reduced to below the normal range at the onset of CHF compared with previous examinations in three cases but increased in five. It appears, therefore, that certain ECG abnormalities, especially AF, and/or progressive ventricular and atrial dilatation, may be indicators of 'occult' DCM in wolfhounds.
authors.affiliation: Department of Small Animal Medicine and Surgery, Royal Veterinary College, Hatfield, Hertfordshire.
authors.forename: S E
authors.initials: SE
authors.lastname: Brownlie
authors.forename: M A
authors.initials: MA
authors.lastname: Cobb
mesh_terms: D017668:Age of Onset; D000818:Animals; D001281:Atrial Fibrillation / Q000662:veterinary; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000503:physiopathology*; D004285:Dogs; D004562:Electrocardiography / Q000662:veterinary; D005260:Female; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*; D008297:Male; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors