title: Evaluation of the left ventricular systolic and diastolic functions by echocardiography in patients with acute leukemia.
abstract: Eighteen patients with acute leukemia were studied to evaluate their left ventricular systolic and diastolic function by M mode, two-dimensional and Doppler echocardiographic techniques. The study group was compared with another group of 18 patients of similar age with iron deficiency anemia. The latter group had a comparable heart rate and levels of Hb. There were no differences in systolic function, whereas the diastolic function was lower in patients with acute leukemia (E/A ratio = 1.1 +/- 0.3 vs. 1.42 +/- 0.5, p < 0.05). It is concluded that left ventricular diastolic dysfunction is more common in patients with acute leukemia and may be an indicator of restrictive cardiomyopathy.
authors.affiliation: Division of General Internal Medicine, Department of Internal Medicine, Cerrahpaşa Medical Faculty, Istanbul University, Istanbul, Turkey. tunckale@atlas.net.tr
authors.forename: A
authors.initials: A
authors.lastname: Tunçkale
authors.forename: B
authors.initials: B
authors.lastname: Ilerigelen
authors.forename: G
authors.initials: G
authors.lastname: Aktuğlu
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D018798:Anemia, Iron-Deficiency / Q000000981:diagnostic imaging / Q000503:physiopathology; D003971:Diastole; D004452:Echocardiography; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007938:Leukemia / Q000000981:diagnostic imaging / Q000503:physiopathology*; D017254:Leukemic Infiltration; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D013599:Systole; D016277:Ventricular Function, Left / Q000502:physiology*