Bacterial spores survive treatment with commercial sterilants and disinfectants.
This study compared the activity of commercial liquid sterilants and disinfectants on Bacillus subtilis spores deposited on three types of devices made of noncorrodible, corrodible, or polymeric material. Products like Renalin, Exspor, Wavicide-01, Cidexplus, and cupric ascorbate were tested under conditions specified for liquid sterilization. These products, at the shorter times indicated for disinfection, and popular disinfectants, like Clorox, Cavicide, and Lysol were also studied. Data obtained with a sensitive and quantitative test suggest that commercial liquid sterilants and disinfectants are less effective on contaminated surfaces than generally acknowledged.
Sagripanti
J L
JL
Molecular Biology Branch (HFZ-113), Division of Life Sciences, Office of Science and Technology, Center for Devices and Radiological Health, Food and Drug Administration, Rockville, Maryland 20857, USA. JUS@CDRH.FDA.GOV
Bonifacino
A
A
D001412:Bacillus subtilis / Q000502:physiology*; D004202:Disinfectants; D004866:Equipment Contamination; D004864:Equipment and Supplies; D012996:Solutions; D013171:Spores, Bacterial / Q000502:physiology*; D013242:Sterilization / Q000379:methods
D004202:Disinfectants; D012996:Solutions