Preoperative pulse wave velocity fails to predict hemodynamic responses to anesthesia and to surgical stimulation.
OBJECTIVE
To determine whether pulse wave velocity (PWV), which is a useful indicator of cardiovascular disease, can predict the hemodynamic responses to anesthesia and surgical stimulation in surgical patients.


METHODS
Prospective, randomized study.


METHODS
Operating rooms at a university hospital.


METHODS
30 ASA physical status I and II female patients presenting for elective gynecologic surgery.


METHODS
Patients who received one of the following anesthesia techniques were studied; isoflurane, sevoflurane and sevoflurane with nitrous oxide (N2O).


RESULTS
Patients underwent preoperative PWV measurements using an automatic PWV measurement device. Systolic blood pressure and heart rate levels were recorded at baseline, during anesthesia, and at skin incision. PWV had no significant correlation with percent changes of systolic blood pressure or heart rate, even after controlling the choice of anesthetic drugs.


CONCLUSIONS
Preoperative PWV fails to predict hemodynamic responses to anesthesia and to surgical stimulation.
Nakata
Y
Y
Department of Anesthesia, Teikyo University School of Medicine, Ichihara Hospital, Chiba, Japan. ynakata@med.teikyo-u.ac.jp
Goto
T
T
Ishiguro
Y
Y
Terui
K
K
Niimi
Y
Y
Morita
S
S
D000328:Adult; D000704:Analysis of Variance; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D001783:Blood Flow Velocity / Q000187:drug effects / Q000502:physiology; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D002339:Carotid Arteries / Q000502:physiology; D017558:Elective Surgical Procedures; D005260:Female; D005263:Femoral Artery / Q000502:physiology; D005544:Forecasting; D013509:Gynecologic Surgical Procedures; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage; D008738:Methyl Ethers / Q000008:administration & dosage; D008875:Middle Aged; D009609:Nitrous Oxide / Q000008:administration & dosage; D011300:Preoperative Care; D011446:Prospective Studies; D011674:Pulse; D012044:Regression Analysis; D000077149:Sevoflurane; D014160:Transducers, Pressure
D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane; D007530:Isoflurane; D009609:Nitrous Oxide