[Modulation of angiogenesis. A new therapeutic tool for vascular diseases].
Angiogenesis permits the growth of new vessels. This process may be modified during the course of some pathological phenomenon, i.e. cancer, atherosclerosis or diabetes. After a brief description of angiogenesis pathophysiology, the therapeutic possibilities in cardiovascular diseases are discussed. Initial results of therapeutic trials in coronary and peripheral artery diseases are detailed, and perspectives for the future are reviewed.
Blot
E
E
Département de Médecine Interne, CHU de Rouen.
Delastre
O
O
Lévesque
H
H
D001162:Arteriosclerosis Obliterans / Q000150:complications; D002303:Cardiac Output, Low / Q000150:complications; D006801:Humans; D007866:Leg / Q000098:blood supply; D009369:Neoplasms / Q000150:complications; D009389:Neovascularization, Pathologic / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D012307:Risk Factors; D014652:Vascular Diseases / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*