Facilitation of sexual behavior in French-Alpine goats treated with intravaginal progesterone-releasing devices and estradiol during the breeding and nonbreeding seasons.
The effectiveness of administering progesterone (P4) using controlled intravaginal drug release (CIDR) devices on estradiol (E2)-induced sexual behaviors was examined in ovariectomized (ovx) French-Alpine goats during the fall and spring. Estradiol-induced attractivity and receptivity were facilitated during the spring when P4-filled CIDR devices were removed 24 or 48 h before injection of 30 microg of E2. During the fall, attractivity was also facilitated by CIDR removal 24 h prior to E2 injection, whereas E2-induced receptivity was unaffected by removal of the CIDR at this interval. Concentrations of P4 in circulation during the 3 d of treatment with a CIDR were similar to those during the late luteal phase of the estrous cycle in intact goats. Treatment with P4-filled CIDR for 3 d, followed by injection with 30 microg of E2 24 h after removal, was determined to be a useful model for inducing sexual behavior in a physiologically relevant manner, and it may also be an effective means for facilitating estrus detection due to the high frequency of display of sexual behavior during a predictable time period following steroid treatment.
Billings
H J
HJ
Department of Animal Sciences, Cook College, Rutgers, The State University of New Jersey, New Brunswick 08901-8525, USA.
Katz
L S
LS
D000282:Administration, Intravaginal; D000818:Animals; D001947:Breeding / Q000379:methods*; D004958:Estradiol / Q000008:administration & dosage / Q000494:pharmacology*; D004971:Estrus / Q000187:drug effects; D005260:Female; D006041:Goats / Q000502:physiology*; D010052:Ovariectomy; D011374:Progesterone / Q000008:administration & dosage / Q000494:pharmacology*; D012621:Seasons; D012726:Sexual Behavior, Animal / Q000187:drug effects*
D011374:Progesterone; D004958:Estradiol