title: MR high-resolution blood oxygenation level-dependent venography of occult (low-flow) vascular lesions.
abstract: A new technique for detecting vascular malformations, high-resolution BOLD venography (HRBV), is described. This technique relies on the BOLD principle for detecting deoxygenated blood in low-flow malformations. HRBV images are acquired using a modified 3D gradient-echo with voxel volumes of 0.5 x 0.5 x 2 mm3. The magnitude data are masked with the phase images to enhance visibility of the venous structures and are displayed using the minimum intensity projection. Preliminary results for 10 patients show that HRBV is more sensitive in detecting cavernomas than is T2-weighted imaging, and lesions that are presumed to be telangiectasias are detected only with this technique.
authors.affiliation: Washington University School of Medicine, St. Louis Children's Hospital, Mallinckrodt Institute of Radiology, MO, USA.
authors.forename: B C
authors.initials: BC
authors.lastname: Lee
authors.forename: K D
authors.initials: KD
authors.lastname: Vo
authors.forename: D K
authors.initials: DK
authors.lastname: Kido
authors.forename: P
authors.initials: P
authors.lastname: Mukherjee
authors.forename: J
authors.initials: J
authors.lastname: Reichenbach
authors.forename: W
authors.initials: W
authors.lastname: Lin
authors.forename: M S
authors.initials: MS
authors.lastname: Yoon
authors.forename: M
authors.initials: M
authors.lastname: Haacke
mesh_terms: D001921:Brain / Q000098:blood supply*; D001932:Brain Neoplasms / Q000175:diagnosis*; D002560:Cerebrovascular Circulation; D006392:Hemangioma, Cavernous / Q000175:diagnosis*; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis*; D018810:Magnetic Resonance Angiography; D010100:Oxygen / Q000097:blood*; D013684:Telangiectasis / Q000175:diagnosis
chemical_list: D010100:Oxygen