Antiinflammatory effect of the aqueous extract from Rumex patientia L. roots.
Pharmacological studies were conducted with the aqueous extract of roots of Rumex patientia L. (Polygonaceae) on experimental animals. For evaluating the antiinflammatory activity, carrageenan, histamine, dextrane, serotonine formaldehyde-induced oedema tests, cotton-pellet granuloma, and Kabak tests in rats were used. The extract was found to possess antiinflammatory activity. Acute toxicity studies revealed that the extract up to a dose of 3 mg/kg orally was nontoxic.
Süleyman
H
H
Department of Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
Demirezer
L O
LO
Kuruüzüm
A
A
Banoğlu
Z N
ZN
Göçer
F
F
Ozbakir
G
G
Gepdiremen
A
A
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000009:adverse effects / Q000494:pharmacology*; D007249:Inflammation / Q000139:chemically induced / Q000188:drug therapy*; D008297:Male; D010936:Plant Extracts / Q000009:adverse effects / Q000494:pharmacology*; D019664:Polygonaceae / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
D000893:Anti-Inflammatory Agents; D010936:Plant Extracts