title: Isolation and amino acid sequence of a peptide with vitellogenesis inhibiting activity from the terrestrial isopod Armadillidium vulgare (Crustacea).
abstract: The complete amino acid sequence of a neuropeptide was established using gas-phase microsequencing, mass spectrometry, and reverse transcription-polymerase chain reaction. This peptide, stored in the sinus gland of the terrestrial isopod Armadillidium vulgare, inhibited vitellogenin synthesis by the fat tissue and inhibited the onset of secondary vitellogenesis when tested in homologous bioassays. This peptide, named Arv-VIH, has 83 amino acid residues and a molecular mass of 9485 Da. Relationships with other related peptides are presented.
authors.affiliation: Génétique et Biologie des Populations de Crustacés, UMR CNRS 6556.
authors.forename: P
authors.initials: P
authors.lastname: Grève
authors.forename: O
authors.initials: O
authors.lastname: Sorokine
authors.forename: T
authors.initials: T
authors.lastname: Berges
authors.forename: C
authors.initials: C
authors.lastname: Lacombe
authors.forename: A
authors.initials: A
authors.lastname: Van Dorsselaer
authors.forename: G
authors.initials: G
authors.lastname: Martin
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002352:Carrier Proteins / Q000737:chemistry* / Q000235:genetics; D002851:Chromatography, High Pressure Liquid; D003445:Crustacea / Q000378:metabolism*; D003488:Cyanogen Bromide; D005260:Female; D007447:Invertebrate Hormones / Q000737:chemistry / Q000235:genetics; D008297:Male; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D009479:Neuropeptides / Q000737:chemistry* / Q000235:genetics; D010446:Peptide Fragments / Q000737:chemistry; D017385:Sequence Homology; D014357:Trypsin; D014818:Vitellogenesis / Q000187:drug effects*
chemical_list: D002352:Carrier Proteins; D007447:Invertebrate Hormones; D009479:Neuropeptides; D010446:Peptide Fragments; C073189:vitellogenesis inhibiting hormone; D014357:Trypsin; D003488:Cyanogen Bromide