The effect of branched chain amino acids on protein synthesis in two skeletal muscles of Japanese quail.
Two different isolated skeletal muscles of Japanese quail were used. The influence of branched chain amino acids on the fractional rate of protein synthesis (FSR) was evaluated using 14C-tyrosine. The addition of 0.5 mM valine, leucine or isoleucine to the incubation medium significantly decreased (P<0.05) the value of FSR in extensor metacarpalis radialis. In the ambiens muscle only the application of leucine increased the FSR significantly while valine and isoleucine were without any effect.
Antalíková
J
J
Institute of Animal Biochemistry and Genetics, Slovak Academy of Sciences, Slovak Republic.
Jankela
J
J
Baranovská
M
M
D000597:Amino Acids, Branched-Chain / Q000494:pharmacology*; D000818:Animals; D003370:Coturnix / Q000378:metabolism*; D007532:Isoleucine / Q000494:pharmacology; D007700:Kinetics; D007930:Leucine / Q000494:pharmacology; D008297:Male; D009124:Muscle Proteins / Q000096:biosynthesis*; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000378:metabolism*; D014633:Valine / Q000494:pharmacology
D000597:Amino Acids, Branched-Chain; D009124:Muscle Proteins; D007532:Isoleucine; D007930:Leucine; D014633:Valine