Aberrant pancreatic tissue accompanied by heterotopic gastric mucosa in the gall-bladder.
A 5 mm pancreatic heterotopia was incidentally identified in the gall-bladder with small cholesterol polyps following cholecystectomy in an asymptomatic 49-year-old female. Microscopically, inflammatory changes in the wall were minimal. The aberrant tissue consisted of acini and ducts but did not have islet formation. Heterotopic gastric mucosal tissue with a mixture of foveolar cells and pyloric glands was seen at the orifice of the pancreatic heterotopia. Islet peptide-immunoreactive endocrine cells were scattered among the pancreatic parenchyma, and the gastric-type gland contained cells positive for gastrin, somatostatin and glucagon. A noteworthy finding was the immunohistochemical detection of a single insulin-containing cell in the pyloric gland.
Murakami
M
M
Tsutsumi
Y
Y
D002828:Choristoma / Q000378:metabolism / Q000473:pathology*; D005260:Female; D005705:Gallbladder Diseases / Q000378:metabolism / Q000473:pathology*; D005753:Gastric Mucosa; D005755:Gastrins / Q000378:metabolism; D005934:Glucagon / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D007328:Insulin / Q000378:metabolism; D008875:Middle Aged; D010179:Pancreas; D013004:Somatostatin / Q000378:metabolism
D005755:Gastrins; D007328:Insulin; D013004:Somatostatin; D005934:Glucagon