title: [A case of frequent intracerebral hemorrhage from mixed vascular malformation in a child].
abstract: We reported a rare case of frequent intracerebral hemorrhage from mixed vascular malformation in an infant. A 1-year and 4-month-old girl was admitted with seizure. She had been diagnosed as having febrile convulsion at the age of 8 months. Computed tomography (CT) indicated a multicystic mass without perifocal edema in the right frontal lobe. The mass was not enhanced by contrast media, but T1-weighted magnetic resonance imaging (MRI) revealed a multicystic mass with mixed signal intensity, while T2-weighted image demonstrated a heterogenous high signal intensity mass with a marginal low intensity rim. These findings suggested a cavernous angioma causing intracerebral hematomas. Because of this, total resection was achieved via a right fronto-temporal craniotomy without neurological deficits. Histologically, numerous dilated venous-type blood vessels interspersed within the normal brain parenchyma were seen. In parts, the vessel walls were abnormally thickened and the lesion coalesced with capillary-like vessels. We diagnosed mixed vascular malformation, mainly composed of venous malformation along with telangiectasia. The number of reports for this so-called mixed vascular malformation have thus been increased. The histopathological criteria for classification of vascular malformation should be reinvestigated carefully.
authors.affiliation: Department of Neurosurgery, Sendai National Hospital, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Uenohara
authors.forename: N
authors.initials: N
authors.lastname: Takahashi
authors.forename: S
authors.initials: S
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Arai
authors.forename: A
authors.initials: A
authors.lastname: Nishino
authors.forename: Y
authors.initials: Y
authors.lastname: Sakurai
mesh_terms: D002543:Cerebral Hemorrhage / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D002538:Intracranial Arteriovenous Malformations / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008279:Magnetic Resonance Imaging; D012008:Recurrence; D013684:Telangiectasis / Q000150:complications; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome