title: The Pandora Project: results of the pilot study.
abstract: The Pandora Project was designed to develop a computer-assisted system to improve the appropriateness and effectiveness of hypertension treatment in clinical practice and to organize a database both for epidemiologic and economic assessments. The feasibility study was conducted by five general practitioners (GP) who enrolled 244 patients over a period of 6 months. The follow-up lasted 6 months. The computer system implemented provided a linkage among GP's office, hypertension unit, Ravenna Health Service databases, and a remote station. A total of 209 patients completed the follow-up period; 56% of patients were not normotensive despite the antihypertensive treatment. The prevalence of overweight, physical inactivity, and family history of high blood pressure and hypercholesterolemia was greater than 50%. Unplanned check-ups by GP occurred 9%. Six patients were admitted to the hospital eight times; 19 patients attended the casualty department 21 times. The mean total direct cost per patient was 567,800 Italian Lire (ITL) and increased to ITL 732,000 or to ITL 825,900 when lost productivity, calculated according to two different formulas, was added. This pilot study confirms the need and feasibility of implementing the Pandora Project in general practice in Ravenna.
authors.affiliation: Department of Nephrology, S.M. delle Croci Hospital, Ravenna, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Degli Esposti
authors.forename: P
authors.initials: P
authors.lastname: Berto
authors.forename: S
authors.initials: S
authors.lastname: Buda
authors.forename: A M
authors.initials: AM
authors.lastname: Di Nardo
authors.forename: A
authors.initials: A
authors.lastname: Sturani
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D017281:Cost of Illness; D016208:Databases, Factual; D004360:Drug Therapy, Computer-Assisted; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000191:economics / Q000453:epidemiology; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects
chemical_list: D000959:Antihypertensive Agents