[Hepatoprotective effect of flower pollen lipid extract in paracetamol-induced hepatotoxicity in mice].
Hepatoprotective effects of the lipid flower pollen extract (LEPK) in paracetamol intoxication in mice were shown. Normalisation of A1AT and LDH--biochemical indicators of necrotic changes in the hepatic cells, and high protection ultrastructural cell organelle such as mitochondrion substantially testifies to the hepatoprotective effect of investigated lipid flower pollen extract on the hepatic cells.
Czarnecki
R
R
Katedra Farmakodynamiki Collegium Medicum UJ.
Librowski
T
T
Polański
M
M
D000082:Acetaminophen / Q000037:antagonists & inhibitors* / Q000633:toxicity; D000818:Animals; D019610:Cytoprotection; D008055:Lipids / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology; D008297:Male; D051379:Mice; D008928:Mitochondria / Q000648:ultrastructure; D009336:Necrosis; D015388:Organelles / Q000648:ultrastructure; D010936:Plant Extracts / Q000494:pharmacology*
D008055:Lipids; D010936:Plant Extracts; D000082:Acetaminophen