title: Early clinical results with a multiple synchronized pulse 1064 NM laser for leg telangiectasias and reticular veins.
abstract: BACKGROUND
  The 1064 nm wavelength penetrates tissue and blood vessels with little absorption by melanin.
  
  
  OBJECTIVE
  To perform a study examining the effects of 1064 nm laser used in pulses from 4 msec to 16 msec on leg telangiectasias ranging in size from 0.5 to 3 mm.
  
  
  METHODS
  In this initial trial, 50 sites on 30 patients were enrolled and treated with a multiple synchronized pulse laser at 1064 nm. The primary parameter utilized was a single 10-16 msec pulse. Improvement was judged by comparison of digital images at 1 month, 2 months, and 3 months posttreatment. Improvement was judged, based on size and number of vessels remaining. Side effects were noted as present or absent at each visit.
  
  
  RESULTS
  Immediate contraction or darkening followed by urtication and visible total vessel closure as indicated by absence of blanching and visual elimination of the vessel border occurred in most of the treated sites. Two 3 mm diameter vessels were confirmed to be closed without flow by Duplex ultrasound visualization, using a 10 MHz transducer. Bruising from vessel rupture was seen in approximately 50% of the cases. No epidermal injury was noted in any sites, even in Fitzpatrick skin Types IV. At 3 months follow-up, 75% improvement was noted at treatment sites.
  
  
  CONCLUSIONS
  Initial clinical results with a new multiple synchronized pulsed 1064 nm laser indicate that this longer wavelength supplied at pulses of up to 16 msec appears to be a valuable modality for immediate closure and subsequent elimination of leg ectatic veins. Epidermal injury is unlikely, as the near infrared wavelength has minimal interaction with melanin.
authors.affiliation: Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Weiss
authors.forename: M A
authors.initials: MA
authors.lastname: Weiss
mesh_terms: D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D013684:Telangiectasis / Q000532:radiotherapy*; D013696:Temperature; D013997:Time Factors; D016896:Treatment Outcome; D014648:Varicose Veins / Q000532:radiotherapy*