title: Long-term follow-up of nineteen cystic lymphangiomas treated with fibrin sealant.
abstract: BACKGROUND
  Surgical exeresis is regarded as the first choice treatment for cystic lymphangioma. Surgery may be extremely complex, giving rise to complications. Several therapeutic methods have been described to avoid the complications derived from the conventional surgical approach. The idea of treating lymphangioma by means of suction and injection of fibrin sealant (Tissucol), is an alternative to surgery.
  
  
  METHODS
  The authors present 19 cases of cystic lymphangioma, treated with fibrin sealant injected into the lesion, during the 1991 to 1997 period. Two of the patients had been treated surgically and experienced recurrence of the tumor previous to treatment. In the other 17 cases, puncture was the only therapy applied. One patient required 3 punctures, another 6 patients required 2 punctures, and only 1 of them, after 2 unsuccessful punctures, was treated with surgical resection. The rest of the 10 cases subsided after the first puncture. Follow-up ranged between 3 and 72 months, with a mean of 40 months.
  
  
  RESULTS
  The ultrasonographic (US) follow-up showed a complete remission in 17 patients treated with puncture. One patient remained with a small intermittent tumor, the appearance of which is related to catarrhal processes, and another patient rejected further puncture after the second one. No complications appeared.
  
  
  CONCLUSIONS
  These results support the fact that the puncture, aspiration, followed by injection of Tissucol, is a choice in the surgical treatment of cystic lymphangioma.
authors.affiliation: Department of Pediatric Surgery, Unidad Integrada Hospital Sant Joan de Déu, Universidad de Barcelona, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Castañón
authors.forename: J
authors.initials: J
authors.lastname: Margarit
authors.forename: R
authors.initials: R
authors.lastname: Carrasco
authors.forename: M
authors.initials: M
authors.lastname: Vancells
authors.forename: A
authors.initials: A
authors.lastname: Albert
authors.forename: L
authors.initials: L
authors.lastname: Morales
mesh_terms: D002675:Child, Preschool; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006258:Head and Neck Neoplasms / Q000601:surgery / Q000628:therapy*; D006801:Humans; D018191:Lymphangioma, Cystic / Q000601:surgery / Q000628:therapy*; D008297:Male; D011677:Punctures; D013396:Suction; D014014:Tissue Adhesives / Q000627:therapeutic use*
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives