Cutaneous T cell lymphoma in children.
Cutaneous T cell lymphoma (CTCL) is a term used to describe a heterogeneous group of lymphoproliferative disorders that involve the skin. Mycosis fungoides and Sézary syndrome are two forms of CTCL that arise in adults and are uncommon in children. Dermatologists frequently employ the term CTCL as a synonym for mycosis fungoides and Sézary syndrome. There has been increased recognition that the mycosis fungoides and Sézary syndrome forms of CTCL may arise in children and adolescents. Moreover, younger adults with these types of CTCL report onset of symptoms during adolescence. The literature regarding CTCL in childhood is limited. The purpose of this article is the review the literature regarding CTCL arising in children. The clinical presentation including morphologic variants, diagnosis, prognosis, and management are summarized.
Garzon
M C
MC
Department of Dermatology and Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
D002648:Child; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000145:classification / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D011379:Prognosis; D012074:Remission Induction; D012867:Skin / Q000473:pathology*