Pulmonary perfusion: respiratory-triggered three-dimensional MR imaging with arterial spin tagging--preliminary results in healthy volunteers.
The authors used a spin-tagging method of magnetic resonance perfusion imaging to measure pulmonary perfusion in eight healthy volunteers with use of a respiratory-triggered three-dimensional pulse sequence. The average signal intensity (SI) decrease upon arterial labeling was 24%. The perfusion SI increased by 21% after exercise (P = .02). Focal blood flow abnormalities were observed in a patient with chronic obstructive pulmonary disease.
Roberts
D A
DA
Department of Radiology, University of Pennsylvania Medical Center, Philadelphia 19104-4283, USA. roberts@oasis.rad.upenn.edu
Gefter
W B
WB
Hirsch
J A
JA
Rizi
R R
RR
Dougherty
L
L
Lenkinski
R E
RE
Leigh
J S
JS
Schnall
M D
MD
D000328:Adult; D015444:Exercise / Q000502:physiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008168:Lung / Q000098:blood supply*; D008173:Lung Diseases, Obstructive / Q000175:diagnosis / Q000503:physiopathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D012039:Regional Blood Flow / Q000502:physiology; D014692:Ventilation-Perfusion Ratio / Q000502:physiology*