Basal cell carcinoma-like epidermal changes overlying dermatofibromas often reveal loss of heterozygosity in the PTCH gene.
Leong
P M
PM
Kauffman
C L
CL
Moresi
J M
JM
Wu
L
L
Jeronimo
C
C
Sidransky
D M
DM
Miller
S J
SJ
D002280:Basal Cell Carcinoma / Q000235:genetics*; D016147:Genes, Tumor Suppressor; D018219:Histiocytoma, Benign Fibrous / Q000235:genetics*; D006801:Humans; D019656:Loss of Heterozygosity; D008565:Membrane Proteins / Q000235:genetics*; D009363:Neoplasm Proteins / Q000235:genetics; D000072079:Patched Receptors; D000072081:Patched-1 Receptor; D011956:Receptors, Cell Surface; D012878:Skin Neoplasms / Q000235:genetics*
D008565:Membrane Proteins; D009363:Neoplasm Proteins; C000606236:PTCH1 protein, human; D000072079:Patched Receptors; D000072081:Patched-1 Receptor; D011956:Receptors, Cell Surface