Use of partial liquid ventilation to manage pulmonary complications of acute verapamil-sustained release poisoning.
BACKGROUND
Verapamil is a papaverine-derived calcium channel blocker widely used for the treatment of hypertension and supraventricular tachyarrhythmias. It is one of the leading agents involved in pharmaceutical poisoning-related deaths among adults.


METHODS
We report a case of severe sustained-release verapamil poisoning associated with respiratory failure in an adult man who survived after receiving 4 days of partial liquid ventilation as a part of his medical management.
Szekely
L A
LA
Massachusetts General Hospital, Boston, USA.
Thompson
B T
BT
Woolf
A
A
D000328:Adult; D000403:Airway Resistance / Q000187:drug effects; D002121:Calcium Channel Blockers / Q000506:poisoning*; D003692:Delayed-Action Preparations / Q000009:adverse effects*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D010100:Oxygen / Q000097:blood; D011859:Radiography; D012128:Respiratory Distress Syndrome / Q000139:chemically induced; D012131:Respiratory Insufficiency / Q000139:chemically induced* / Q000628:therapy; D013406:Suicide, Attempted; D014691:Ventilation / Q000379:methods*; D014700:Verapamil / Q000506:poisoning*
D002121:Calcium Channel Blockers; D003692:Delayed-Action Preparations; D014700:Verapamil; D010100:Oxygen