title: Steroid-refractory neonatal eosinophilic pneumonia responsive to cyclosporin A.
abstract: Idiopathic neonatal eosinophilic pneumonia is extremely rare. We report an infant who presented with tachypnea and interstitial infiltrates on chest radiograph at age 2 wk. Lung biopsy revealed perivascular and interstitial eosinophils. Despite initial improvement, the patient's condition became resistant to corticosteroids, cromolyn, and intravenous gamma globulin. After treatment with cyclosporin A his symptoms resolved.
authors.affiliation: Department of Pediatrics, University of Louisville, Louisville, Kentucky, USA.
authors.forename: R L
authors.initials: RL
authors.lastname: Morton
authors.forename: L R
authors.initials: LR
authors.lastname: Shoemaker
authors.forename: N S
authors.initials: NS
authors.lastname: Eid
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use*; D018432:Drug Resistance, Multiple; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007231:Infant, Newborn; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D011657:Pulmonary Eosinophilia / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011241:Prednisone