title: Magnetic resonance imaging and ultrasonography in the diagnosis of a malignant peripheral nerve sheath tumor in a dog.
abstract: A 9-year-old male neutered mixed breed dog had a two-month history of progressive left thoracic limb lameness. There was electromyographic evidence of denervation potentials in all muscles of this limb. In magnetic resonance images a multilobulated, hyperintense mass was visible caudal to the middiaphysis of the left humerus on T-2 weighted images. The mass, which was isointense with surrounding tissue on T1 weighted images, extended proximally towards the brachial plexus. The mass was also visible as a fusiform structure of mixed echogenicity sonographically, although fine-needle aspiration performed at this time was nondiagnostic. A malignant peripheral nerve sheath tumor was diagnosed histopathologically.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610, USA.
authors.forename: S R
authors.initials: SR
authors.lastname: Platt
authors.forename: J
authors.initials: J
authors.lastname: Graham
authors.forename: C L
authors.initials: CL
authors.lastname: Chrisman
authors.forename: K
authors.initials: K
authors.lastname: Collins
authors.forename: S
authors.initials: S
authors.lastname: Chandra
authors.forename: J
authors.initials: J
authors.lastname: Sirninger
authors.forename: S M
authors.initials: SM
authors.lastname: Newell
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001707:Biopsy, Needle / Q000662:veterinary; D001917:Brachial Plexus / Q000000981:diagnostic imaging / Q000473:pathology*; D004283:Dog Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D004285:Dogs; D004576:Electromyography / Q000662:veterinary; D005552:Forelimb / Q000294:innervation*; D006811:Humerus / Q000294:innervation; D007794:Lameness, Animal / Q000175:diagnosis / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging / Q000662:veterinary*; D008297:Male; D018482:Muscle, Skeletal / Q000294:innervation; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000662:veterinary*; D009919:Orchiectomy / Q000662:veterinary; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000662:veterinary*; D014463:Ultrasonography