title: [An effective case of a new biological adhesive agent, gelatin-resorcinol formaldehyde-glutaralhyde glue (GRFG-glue) in treating refractory pulmonary fistula following lobectomy for pulmonary aspergilloma].
abstract: We report a successful case of thoracoscopic therapy using a new biological adhesive agent, Gelatin-Resorcinol Formaldehyde glue (GRFG glue) for refractory pulmonary fistula. A 69-year-old male underwent right upper lobectomy for lung aspergilloma. Air leakage began 11 days after lobectomy. Closing alveolar fistula was performed 28 days after first operation. Relapsing air leakage began 2 days after second operation. The insertion of fibrin glue through thoracoscope at two times was not effective for refractory pulmonary fistula. But the insertion of GRFG glue was effective to close the fistula completely.
authors.affiliation: Department of Thoracic Surgery, National Sanyo Hospital, Ube, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Umemori
authors.forename: S
authors.initials: S
authors.lastname: Makihara
authors.forename: T
authors.initials: T
authors.lastname: Fukuhara
authors.forename: K
authors.initials: K
authors.lastname: Kotani
authors.forename: R
authors.initials: R
authors.lastname: Eda
mesh_terms: D000368:Aged; D001228:Aspergillosis / Q000601:surgery*; D004338:Drug Combinations; D005402:Fistula / Q000209:etiology / Q000628:therapy*; D005557:Formaldehyde / Q000627:therapeutic use*; D005780:Gelatin / Q000627:therapeutic use*; D005976:Glutaral / Q000627:therapeutic use*; D006801:Humans; D008171:Lung Diseases / Q000209:etiology / Q000628:therapy*; D008172:Lung Diseases, Fungal / Q000601:surgery*; D008297:Male; D011013:Pneumonectomy / Q000009:adverse effects*; D011183:Postoperative Complications / Q000628:therapy*; D012118:Resorcinols / Q000627:therapeutic use*; D013906:Thoracoscopy; D014014:Tissue Adhesives / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D012118:Resorcinols; D014014:Tissue Adhesives; C083703:gelatin-resorcin-formaldehyde-glutaraldehyde adhesive; D005557:Formaldehyde; D005780:Gelatin; D005976:Glutaral