Idiopathic hypoparathyroidism associated with adult rheumatoid arthritis.
A 48-year-old female patient with adult onset idiopathic hypoparathyroidism diagnosed at the age of 28 years developed a typical seropositive rheumatoid arthritis (RA) at 46 years of age after several years of evolution of a palindromic rheumatism. Only one case of an association between idiopathic hypoparathyroidism and RA has been described in the medical literature. Autoimmunity seems to play a pivotal role in the aetiopathogenesis of both diseases, and could explain the nature of this association; nevertheless, a chance association could not be excluded.
Salvador
G
G
Department of Rheumatology, Hospital Clínic i Provincial, Barcelona, Spain.
Sanmartí
R
R
Ros
I
I
Halperin
I
I
Cañete
J D
JD
Orellana
C
C
Muñoz-Gomez
J
J
D015502:Absorptiometry, Photon; D000483:Alleles; D000974:Antibodies, Antinuclear / Q000032:analysis; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging / Q000209:etiology* / Q000276:immunology / Q000378:metabolism; D015519:Bone Density; D002118:Calcium / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006684:HLA-DR Antigens / Q000235:genetics / Q000276:immunology; D059811:HLA-DRB1 Chains; D006801:Humans; D007011:Hypoparathyroidism / Q000150:complications* / Q000000981:diagnostic imaging / Q000276:immunology / Q000378:metabolism; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood
D000974:Antibodies, Antinuclear; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; D010281:Parathyroid Hormone; D002118:Calcium