title: The logistics and cost-effectiveness of circulatory support: advantages of the ABIOMED BVS 5000.
abstract: BACKGROUND
  In 1994, the ABIOMED BVS 5000 was incorporated into our acute cardiac assist armamentarium. This report is a general overview of our experience. A hypothetical cost analysis focusing on specific devices and device-related personnel contrasted the BVS 5000 with our prior model of centrifugal pump use.
  
  
  METHODS
  In 3 years, 22 patients were supported with the BVS 5000, as a biventricular assist device in 40%, right ventricular assist device in 27%, and left ventricular assist device in 32%. Indications were postcardiotomy support in 12, acute myocarditis in 2, bridge to transplant in 4, and failed heart transplant in 4. The cost analysis was performed retrospectively. The actual cost of disposable blood pumps, including replacement pumps, and cannulae constituted the BVS cost. The hypothetical centrifugal costs included the disposables, replacement cones, as well as the labor costs of the continuous perfusionist coverage.
  
  
  RESULTS
  Of the 22 patients, 10 (45%) were weaned and 13 (59%) were successfully discharged. Five patients were transplanted while on BVS 5000 support, accounting for a higher rate of discharge. Comparison of "actual" BVS costs with "projected" centrifugal costs revealed differences based upon the intended application of the BVS. In bridge-to-transplant patients with long duration of support, the daily cost of support was dramatically lower with the BVS 5000. For short-term postcardiotomy support, acute myocarditis, or failed transplant, the differences were small.
  
  
  CONCLUSIONS
  Because the BVS 5000 was readily managed by the intensive care unit nursing staff, this system displaced centrifugal systems in our program. Outcome measures of weaning and successful discharge were improved relative to our prior experience with centrifugal pumps. Even without taking indirect costs into account, the hypothetical cost analysis supported continued use of the BVS system for acute cardiac assistance.
authors.affiliation: Division of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
authors.forename: G S
authors.initials: GS
authors.lastname: Couper
authors.forename: R J
authors.initials: RJ
authors.lastname: Dekkers
authors.forename: D H
authors.initials: DH
authors.lastname: Adams
mesh_terms: D000328:Adult; D000818:Animals; D002642:Chick Embryo; D003362:Cost-Benefit Analysis; D003365:Costs and Cost Analysis; D004867:Equipment Design / Q000191:economics; D005260:Female; D006333:Heart Failure / Q000191:economics* / Q000209:etiology / Q000601:surgery; D006353:Heart-Assist Devices / Q000191:economics*; D006801:Humans; D007902:Length of Stay / Q000191:economics; D008297:Male; D008875:Middle Aged; D010348:Patient Care Team / Q000191:economics; D019057:Quality-Adjusted Life Years; D014481:United States