title: Glutathione reductase activity and flavin concentration in guinea-pig tissues.
abstract: Glutathione reductase (GR) activity and flavin concentration were studied in systemic tissues (brain, heart, lung, liver, spleen, stomach, pancreas, muscle, kidney, testis) and blood components (erythrocytes and plasma) from male guinea-pigs. GR activity and the flavin concentration were high in kidney and liver, and low in muscle. GR activity in erythrocytes was found in a range of tissues, but flavin concentration in erythrocytes was lower than in any tissues. GR was saturated with flavin adenine dinucleotide (FAD) in almost all tissues, but not in muscle or erythrocytes.
authors.affiliation: Japan Lypophilization Laboratory, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Muraoka
authors.forename: M
authors.initials: M
authors.lastname: Kurata
authors.forename: N S
authors.initials: NS
authors.lastname: Agar
mesh_terms: D000818:Animals; D004912:Erythrocytes / Q000378:metabolism; D005182:Flavin-Adenine Dinucleotide / Q000378:metabolism; D005415:Flavins / Q000378:metabolism*; D005980:Glutathione Reductase / Q000378:metabolism*; D006168:Guinea Pigs / Q000378:metabolism*; D008297:Male; D012016:Reference Values; D014018:Tissue Distribution
chemical_list: D005415:Flavins; D005182:Flavin-Adenine Dinucleotide; D005980:Glutathione Reductase