Cancer gene and immunotherapy: recent developments.
Gene and immunotherapeutic approaches to treat human malignant tumors are reviewed. Special attention is given to the different strategies of cancer gene therapy and to recent aspects of cytokine-supported tumor immunotherapy or tumor-specific vaccination. The limitations of these therapy approaches are critically discussed especially with respect to immune escape mechanisms.
Jantscheff
P
P
Department of Research/Molecular Cancer Research, Kantonsspital, Basel, Switzerland. jantscheff@ubaclu.unibas.ch
Herrmann
R
R
Rochlitz
C
C
D000818:Animals; D000951:Antigens, Neoplasm / Q000276:immunology; D019496:Cancer Vaccines / Q000276:immunology; D016207:Cytokines / Q000627:therapeutic use; D015316:Genetic Therapy; D006801:Humans; D007167:Immunotherapy; D008545:Melanoma / Q000276:immunology; D009369:Neoplasms / Q000276:immunology / Q000628:therapy*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D019139:Tumor Escape
D000951:Antigens, Neoplasm; D019496:Cancer Vaccines; D016207:Cytokines