Characterization of a novel HLA-A*24 allele containing an HLA-A*03 sequence motif.
HLA-A*2418 is described for the first time. It segregates in a Mendelian fashion. Serological analyses indicate that the new allele encodes epitopes from both HLA-A9 and -A3 specificities. Results from nucleotide sequencing analyses of polymerase chain reaction (PCR) amplification products derived from genomic and cDNA are compatible with those findings.
Drábek
J
J
Department of Immunology, Teaching Hospital, Olomouc, The Czech Republic.
Bunce
M
M
Faé
I
I
Ambruzová
Z
Z
Dunn
P
P
Ross
J
J
Fischer
G F
GF
D000483:Alleles; D001483:Base Sequence; D015234:HLA-A Antigens / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA
D015234:HLA-A Antigens