title: Developmental changes in the distribution of cecal lectin-binding sites of Balb-c mice.
abstract: The existence of lectin-binding sites was investigated in the cecum of Balb-c mice at seven developmental stages ranging from 18 days post conception (p.c.) to 8 weeks after birth. Nine horseradish-peroxidase-conjugated lectins (concanavalin A, Triticum vulgaris, Dolichus biflorus, Helix pomatia, Arachis hypogaea, Glycine maximus, Lotus tetragonolobus, Ulex europaeus, Limulus polyphemus) were applied to 5- to 7-microns thin paraffin sections of Bouin-fixed tissue. After DAB staining the sections were evaluated by light microscopy. It was shown that each lectin exhibits a unique developmental pattern. The adult binding patterns were established at the age of 3-4 weeks with only minor changes occurring thereafter. Considerable differences in binding patterns occurred not only between lectins of different groups but also between lectins with the same nominal monosaccharide specificity.
authors.affiliation: Division of Oral Biology and Pathology, University of Queensland, Brisbane, Australia.
authors.forename: S
authors.initials: S
authors.lastname: Doehrn
authors.forename: W
authors.initials: W
authors.lastname: Breipohl
authors.forename: W
authors.initials: W
authors.lastname: Lierse
authors.forename: K
authors.initials: K
authors.lastname: Romaniuk
authors.forename: W
authors.initials: W
authors.lastname: Young
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D001665:Binding Sites; D002432:Cecum / Q000196:embryology / Q000378:metabolism*; D005260:Female; D037102:Lectins / Q000145:classification / Q000378:metabolism*; D051379:Mice; D008807:Mice, Inbred BALB C; D011247:Pregnancy; D011975:Receptors, Mitogen / Q000378:metabolism*
chemical_list: D037102:Lectins; D011975:Receptors, Mitogen