title: [Magnetic resonance tomography in stroke--its methodological bases and clinical use].
abstract: Stroke is the third leading cause of death. Until recently, no diagnostic technique was available that could reliably depict ischemic tissue within a therapeutically promising time window. Since the beginning of this decade, a fundamental change has taken place: Perfusion- and diffusion-MRI have shown to be capable of depicting the ischemic injury immediately after vessel occlusion. While perfusion MRI is sensitive to abnormalities in cerebral capillary blood flow (micro-circulation), diffusion MRI indicates tissue damage on a cellular level. Combining perfusion- and diffusion-MRI with standard MR technique (T2-weighted sequences, MR angiography) results in an MR protocol that is complementary and gives insight into both structural and functional parameters.
authors.affiliation: Abteilung Neuroradiologie, Klinikum der Universität Heidelberg. Sabine_Heiland@med.uni-heidelberg.de
authors.forename: S
authors.initials: S
authors.lastname: Heiland
authors.forename: K
authors.initials: K
authors.lastname: Sartor
mesh_terms: D016477:Artifacts; D001921:Brain / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000175:diagnosis*; D003287:Contrast Media; D004058:Diffusion; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods / Q000706:statistics & numerical data; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000706:statistics & numerical data; D010477:Perfusion
chemical_list: D003287:Contrast Media