The anti-factor D antibody, MAb 166-32, inhibits the alternative pathway of the human complement system.
Tanhehco
E J
EJ
Department of Pharmacology, University of Michigan Medical School, Ann Arbor, USA.
Kilgore
K S
KS
Liff
D A
DA
Murphy
K L
KL
Fung
M S
MS
Sun
W N
WN
Sun
C
C
Lucchesi
B R
BR
D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D003167:Complement Activation / Q000187:drug effects; D011416:Complement Factor D / Q000276:immunology*; D003170:Complement Pathway, Alternative / Q000187:drug effects*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D009206:Myocardium / Q000276:immunology; D011817:Rabbits
D000911:Antibodies, Monoclonal; C493488:CFD protein, human; D011416:Complement Factor D