Peroxisome proliferator-activated receptors: mediators of a fast food impact on gene regulation.
Peroxisome proliferator-activated receptors are nuclear receptors with pleiotropic effects on intra- and extracellular lipid metabolism, glucose homeostasis, inflammation control, and cell proliferation. This review addresses the respective roles of the different peroxisome proliferator-activated receptor isoforms in these different processes.
Gelman
L
L
Département d'Athérosclérose, Institut Pasteur de Lille, France.
Auwerx
J
J
D000818:Animals; D015992:Body Mass Index; D004435:Eating / Q000502:physiology*; D005786:Gene Expression Regulation / Q000502:physiology*; D005947:Glucose / Q000378:metabolism; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D050356:Lipid Metabolism; D009374:Neoplasms, Experimental / Q000503:physiopathology; D020033:Protein Isoforms / Q000502:physiology; D018160:Receptors, Cytoplasmic and Nuclear / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology*
D020033:Protein Isoforms; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors; D005947:Glucose