title: Pulmonary perfusion: respiratory-triggered three-dimensional MR imaging with arterial spin tagging--preliminary results in healthy volunteers.
abstract: The authors used a spin-tagging method of magnetic resonance perfusion imaging to measure pulmonary perfusion in eight healthy volunteers with use of a respiratory-triggered three-dimensional pulse sequence. The average signal intensity (SI) decrease upon arterial labeling was 24%. The perfusion SI increased by 21% after exercise (P = .02). Focal blood flow abnormalities were observed in a patient with chronic obstructive pulmonary disease.
authors.affiliation: Department of Radiology, University of Pennsylvania Medical Center, Philadelphia 19104-4283, USA. roberts@oasis.rad.upenn.edu
authors.forename: D A
authors.initials: DA
authors.lastname: Roberts
authors.forename: W B
authors.initials: WB
authors.lastname: Gefter
authors.forename: J A
authors.initials: JA
authors.lastname: Hirsch
authors.forename: R R
authors.initials: RR
authors.lastname: Rizi
authors.forename: L
authors.initials: L
authors.lastname: Dougherty
authors.forename: R E
authors.initials: RE
authors.lastname: Lenkinski
authors.forename: J S
authors.initials: JS
authors.lastname: Leigh
authors.forename: M D
authors.initials: MD
authors.lastname: Schnall
mesh_terms: D000328:Adult; D015444:Exercise / Q000502:physiology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008168:Lung / Q000098:blood supply*; D008173:Lung Diseases, Obstructive / Q000175:diagnosis / Q000503:physiopathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D012039:Regional Blood Flow / Q000502:physiology; D014692:Ventilation-Perfusion Ratio / Q000502:physiology*