RADHA--a new male germ line-specific chromosomal protein of Drosophila.
A new chromosomal protein - RADHA - of Drosophila is described that is specific for the male germ line. It is encoded by a single-copy gene, located in the region 96C-D of D. melanogaster polytene chromosomes. Transcription of the radha gene is restricted to the primary spermatocyte stage. The protein initially accumulates in some of the Y-chromosomal lampbrush loops. After meiosis it is found in the nuclei of spermatids and might be involved in chromatin rearrangement processes in the male germ line. RADHA is a basic protein with a C-terminal leucine zipper region and several segments capable of forming coiled-coil structures.
Harhangi
H R
HR
Department of Physiological Chemistry and Pathobiochemistry, Johannes-Gutenberg University, Duesbergweg 6, D-55099 Mainz, Germany.
Sun
X
X
Wang
Y X
YX
Akhmanova
A
A
Miedema
K
K
Heyting
C
C
Hennig
W
W
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004247:DNA; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000235:genetics*; D019476:Insect Proteins / Q000235:genetics*; D008297:Male; D008969:Molecular Sequence Data; D013090:Spermatocytes / Q000378:metabolism*; D013737:Testis / Q000166:cytology / Q000378:metabolism; D014158:Transcription, Genetic
D029721:Drosophila Proteins; D019476:Insect Proteins; C121780:RHA protein, Drosophila; D004247:DNA