title: Glomerulonephritis without IgA deposits in a case of Henoch-Schönlein purpura.
abstract: A boy aged 3 years 8 months with Henoch-Schönlein purpura (HSP) developed significant proteinuria with hematuria 2 days after the appearance of purpura rash. Although thought to be purpura nephritis, a percutaneous renal biopsy revealed diffuse mesangial proliferative glomerulonephritis (MesPGN) without deposition of immunoglobulin A or complement. Since his urine screening test during a health check at the age of 3.5 years had been unremarkable, HSP might have played a role in the pathogenesis of his non-IgA MesPGN. To our knowledge, non-IgA MesPGN is an uncommon renal manifestation of HSP.
authors.affiliation: Division of Pediatrics, Iwate Prefectural Kitakami Hospital, Kitakami, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.forename: N
authors.initials: N
authors.lastname: Onodera
authors.forename: S
authors.initials: S
authors.lastname: Waga
authors.forename: N
authors.initials: N
authors.lastname: Monma
mesh_terms: D002675:Child, Preschool; D003165:Complement System Proteins / Q000378:metabolism; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications* / Q000209:etiology*; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications*; D007070:Immunoglobulin A / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism* / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron
chemical_list: D007070:Immunoglobulin A; D003165:Complement System Proteins