Human therapeutic cloning.
Somatic cell nuclear 'reprogramming' in livestock species is now routine in many laboratories. Here, Robert Lanza, Jose Cibelli and Michael West discuss how these techniques may soon be used to clone genetically matched cells and tissues for transplantation into patients suffering from a wide range of disorders that result from tissue loss or dysfunction.
Lanza
R P
RP
Tissue Engineering and Transplant Medicine, Advanced Cell Technology, One Innovation Drive, Worcester, Massachusetts 01605, USA. rlanza@advancedcell.com
Cibelli
J B
JB
West
M D
MD
D000818:Animals; D033421:Beginning of Human Life; D001675:Bioethics; D001709:Biotechnology / Q000331:legislation & jurisprudence; D001755:Blastocyst / Q000166:cytology / Q000378:metabolism; D002454:Cell Differentiation; D002678:Chimera / Q000235:genetics; D019976:Cloning, Organism / Q000331:legislation & jurisprudence; D033041:Embryo Research; D004624:Embryo Transfer; D005818:Genetic Engineering / Q000331:legislation & jurisprudence; D006801:Humans; D019369:Life; D053652:Nuclear Transfer Techniques; D018570:Risk Assessment; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism; D014183:Transplantation, Heterologous