title: Histologic studies of the effects of circulating hot saline on the uterus before hysterectomy.
abstract: OBJECTIVE
  To evaluate a new device for endometrial ablation.
  
  
  METHODS
  (Canadian Task Force classification II-1).
  
  
  METHODS
  University-affiliated hospital.
  
  
  METHODS
  Thirty-two women scheduled for hysterectomy.
  
  
  METHODS
  Endometrial ablation and hysterectomy.
  
  
  RESULTS
  The new device for endometrial ablation was evaluated by studying depth of necrosis after staining for the oxidative enzyme NADH. Uniform endomyometrial necrosis was achieved at a depth of 2 to 4 mm with 90 degrees C saline circulated for 10 minutes.
  
  
  CONCLUSIONS
  The procedure was successful in all patients, and there were no adverse clinical sequelae. (J Am Assoc Gynecol Laparosc 6(3):269-273, 1999)
authors.affiliation: Department of Pathology, Columbia University College of Physicians and Surgeons, New York, New York, USA.
authors.forename: R M
authors.initials: RM
authors.lastname: Richart
authors.forename: G B
authors.initials: GB
authors.lastname: das Dores
authors.forename: S M
authors.initials: SM
authors.lastname: Nicolau
authors.forename: G R
authors.initials: GR
authors.lastname: Focchi
authors.forename: V C
authors.initials: VC
authors.lastname: Cordeiro
mesh_terms: D004564:Electrocoagulation / Q000379:methods; D004717:Endometrium / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006358:Hot Temperature; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D015907:Hysteroscopy / Q000379:methods; D011300:Preoperative Care; D012680:Sensitivity and Specificity; D012965:Sodium Chloride / Q000008:administration & dosage*; D014592:Uterine Hemorrhage / Q000601:surgery*
chemical_list: D012965:Sodium Chloride