title: Chronic rheumatoid arthritis complicated by myeloperoxidase antineutrophil cytoplasmic antibody-associated nephritis.
abstract: We report a myeloperoxidase antineutrophil cytoplasmic antibody-positive rheumatoid arthritis patient who developed necrotizing crescentic glomerulonephritis. Steroid therapy was given combined with an immunosuppressant agent, and double-filtration plasmapheresis was started with the aim of removing antibodies from the blood. This therapeutic regimen was found to be useful.
authors.affiliation: Second Department of Internal Medicine, Hiroshima University School of Medicine, Hiroshima, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Yorioka
authors.forename: Y
authors.initials: Y
authors.lastname: Taniguchi
authors.forename: D
authors.initials: D
authors.lastname: Amimoto
authors.forename: H
authors.initials: H
authors.lastname: Miyata
authors.forename: M
authors.initials: M
authors.lastname: Yamakido
authors.forename: T
authors.initials: T
authors.lastname: Taguchi
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000276:immunology*; D001172:Arthritis, Rheumatoid / Q000150:complications*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005921:Glomerulonephritis / Q000150:complications* / Q000276:immunology / Q000628:therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008775:Methylprednisolone / Q000627:therapeutic use; D009195:Peroxidase / Q000276:immunology*; D010956:Plasmapheresis
chemical_list: D000893:Anti-Inflammatory Agents; D019268:Antibodies, Antineutrophil Cytoplasmic; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D009195:Peroxidase; D008775:Methylprednisolone