title: Histopathologic study of presumed parafoveal telangiectasis.
abstract: OBJECTIVE
  To report the postmortem histopathologic features that closely resemble the clinical features of parafoveal telangiectasis.
  
  
  METHODS
  Light and electron microscopy.
  
  
  RESULTS
  Histopathologic features included macular edema; telangiectatic vessels; retinal, subretinal, and superficial retinal neovascularization; retinal pigment epithelial hyperplasia around neovascular aggregates; retinal-choroidal vascular anastomosis; and superficial pigmented cells with lipofuscin.
  
  
  CONCLUSIONS
  The postmortem histopathologic findings in a 36-year-old woman with Down syndrome and other systemic conditions correlate with features noted in previous reports of presumed parafoveal telangiectasis.
authors.affiliation: Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
authors.forename: B
authors.initials: B
authors.lastname: Eliassi-Rad
authors.forename: W R
authors.initials: WR
authors.lastname: Green
mesh_terms: D000328:Adult; D001159:Arterio-Arterial Fistula / Q000209:etiology / Q000473:pathology; D002829:Choroid / Q000098:blood supply / Q000648:ultrastructure; D004314:Down Syndrome / Q000150:complications; D017809:Fatal Outcome; D005260:Female; D005584:Fovea Centralis / Q000098:blood supply* / Q000648:ultrastructure; D006801:Humans; D008269:Macular Edema / Q000209:etiology / Q000473:pathology; D012161:Retinal Artery / Q000002:abnormalities; D012164:Retinal Diseases / Q000209:etiology / Q000473:pathology*; D015861:Retinal Neovascularization / Q000209:etiology / Q000473:pathology; D013684:Telangiectasis / Q000150:complications / Q000473:pathology*