Possible mechanisms of induction of renal tubule cell neoplasms in rats associated with alpha 2u-globulin: role of protein accumulation versus ligand delivery to the kidney.
Melnick
R L
RL
National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
Kohn
M C
MC
D000510:Alpha-Globulins / Q000187:drug effects / Q000652:urine*; D000818:Animals; D002273:Carcinogens / Q000009:adverse effects; D004195:Disease Models, Animal; D004781:Environmental Exposure; D007674:Kidney Diseases / Q000139:chemically induced / Q000209:etiology; D007680:Kidney Neoplasms / Q000139:chemically induced / Q000209:etiology*; D007684:Kidney Tubules / Q000187:drug effects / Q000473:pathology*; D008024:Ligands; D008297:Male; D011485:Protein Binding; D051381:Rats; D012737:Sex Factors; D013045:Species Specificity
D000510:Alpha-Globulins; D002273:Carcinogens; D008024:Ligands