title: [Clinico-pathogenetic variants of DIC syndrome in patients with severe craniocerebral trauma].
abstract: Detection of clinical and pathogenetic variants of the DIC syndrome for development of its differentiated therapy in multiple-modality treatment of severe craniocerebral injury was the purpose of this study. A total of 170 patients with grave craniocerebral injury were examined. The hemostasis system was studied by the following methods: analysis of platelet hemostasis, general coagulation tests, fibrinolysis evaluation, detection of physiological anticoagulants and markers of intravascular blood coagulation and fibrinolysis. Based on the clinical (intra- and extracranial) symptoms and results of studies of the hemostasis system, 3 clinical pathogenetic variants of the DIC syndrome were distinguished, which should be borne in mine when treating patients with severe craniocerebral injury developing the DIC syndrome.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Churliaev
authors.forename: V G
authors.initials: VG
authors.lastname: Lychev
authors.forename: N N
authors.initials: NN
authors.lastname: Epifantseva
authors.forename: A G
authors.initials: AG
authors.lastname: Afanas'ev
mesh_terms: D000293:Adolescent; D000328:Adult; D001780:Blood Coagulation Tests; D001930:Brain Injuries / Q000097:blood / Q000150:complications*; D004211:Disseminated Intravascular Coagulation / Q000145:classification / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D005342:Fibrinolysis; D015600:Glasgow Coma Scale; D006801:Humans; D008297:Male; D008875:Middle Aged