title: Determination of ornidazole in pharmaceutical dosage forms based on reduction at an activated glassy carbon electrode.
abstract: The electrochemical reduction of ornidazole was studied at a glassy carbon electrode activated by applying a new pretreatment. The dependence of intensities of currents and potentials on pH, concentration, scan rate, nature of the solvent (aqueous media, mixed aqueous-organic systems) and surfactant was investigated. Linear calibration plots were obtained over the concentration ranges 4x10(-6)-6x10(-4) and 6x10(-6)-6x10(-4) mol l(-1) in 0.2 M H(2)SO(4) and acetate buffer (pH 4.7), respectively. The method was applied to the determination of ornidazole in different drug formulations.
authors.affiliation: Ankara University, Faculty of Pharmacy, Department of Analytical Chemistry, 06100 Ankara, Turkey
authors.initials: SA
authors.lastname: Özkan
authors.initials: Z
authors.lastname: Senturk
authors.initials: I
authors.lastname: Biryol