title: Rabies vaccine. Developments employing molecular biology methods.
abstract: Rabies vaccines produced by means of molecular biology are described. Recombinant vaccines employing either viruses as vectors (vaccinia, adenovirus, poxvirus, baculovirus, plant viruses) or a plasmid vector carrying the rabies virus glycoprotein gene are discussed. Synthetic peptide technology directed to rabies vaccine production is also presented.
authors.affiliation: Servicio Vacuna Antirrábica, Instituto Nacional de Producción de Biológicos, A.N.L.I.S., Buenos Aires, Argentina. mhedrera@ffyb.UBA.AR
authors.forename: C C
authors.initials: CC
authors.lastname: Paolazzi
authors.forename: O
authors.initials: O
authors.lastname: Pérez
authors.forename: J
authors.initials: J
authors.lastname: De Filippo
mesh_terms: D000256:Adenoviridae / Q000235:genetics; D000818:Animals; D000956:Antigens, Viral; D016367:Baculoviridae / Q000235:genetics; D004274:DNA, Recombinant / Q000235:genetics; D005822:Genetic Vectors; D006023:Glycoproteins / Q000235:genetics; D006801:Humans; D008957:Models, Genetic; D010942:Plant Viruses / Q000235:genetics; D011212:Poxviridae / Q000235:genetics; D011818:Rabies / Q000517:prevention & control* / Q000821:virology*; D011819:Rabies Vaccines / Q000235:genetics*; D014614:Vaccines, Synthetic / Q000235:genetics; D014616:Vaccinia virus / Q000235:genetics; D014759:Viral Envelope Proteins / Q000235:genetics
chemical_list: D000956:Antigens, Viral; D004274:DNA, Recombinant; D006023:Glycoproteins; D011819:Rabies Vaccines; D014614:Vaccines, Synthetic; D014759:Viral Envelope Proteins; C064951:glycoprotein G, Rabies virus