title: [Limitations of the common pre-processing method in the signal-averaged electrocardiogram].
abstract: The isolation of the micro potentials from electrocardiogram using coherence averaging technique requires perfect signal alignment. The purpose of this paper was to assess the reliability of the maximum correlation coefficient (MCC) method by computer simulation. The ability of signal recognition, the impacts of correlation-window-width and threshold on accuracy of temporal alignment and on averaged results were analyzed. The results showed that the MCC method was totally insensitive to amplitude variation and relatively insensitive to the duration variation. In the process of signal alignment, the narrower correlation-window-width, the less sensitivity of the maximum correlation coefficient to the misalignment would be. With the threshold of 0.99, the window-width of both 40 and 100 ms induced the deformation on averaged result in time and frequency domain. The simulation results suggested that the deficiencies of MCC method could impose serious limitations on reliability of isolating the atrial and ventricular late potentials.
authors.affiliation: Institute of Basic Medical Sciences, CAMS, Beijing.
authors.forename: X
authors.initials: X
authors.lastname: Cheng
authors.forename: J
authors.initials: J
authors.lastname: Lin
authors.forename: Z
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D003198:Computer Simulation; D004562:Electrocardiography / Q000379:methods; D012815:Signal Processing, Computer-Assisted