Hyphema associated with pupillary dilation in a patient with exfoliation glaucoma and warfarin therapy.
OBJECTIVE
To describe an unusual hemorrhagic complication associated with pupillary dilation in a patient with exfoliation glaucoma taking anticoagulation therapy.


METHODS
A 78-year-old woman with bilateral exfoliation glaucoma who was receiving warfarin, 2 mg daily, for systemic anticoagulation developed acute visual loss in the right eye several hours after pupillary dilation.


RESULTS
Examination disclosed bilateral advanced exfoliation glaucoma, localized vascularized iridolenticular adhesions in the right eye, and a 4-mm layered hyphema in the right eye.


CONCLUSIONS
Patients with exfoliation glaucoma and vascularized posterior synechiae who are receiving anticoagulation therapy are at increased risk for visually significant spontaneous hyphema after pupillary dilation.
Greenfield
D S
DS
Department of Ophthalmology, New York Eye and Ear Infirmary, New York, USA. dgreenfield@bpei.med.miami.edu
Liebmann
J M
JM
Ritch
R
R
D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000150:complications / Q000188:drug therapy; D002217:Carbachol / Q000627:therapeutic use; D002561:Cerebrovascular Disorders / Q000150:complications / Q000188:drug therapy; D004359:Drug Therapy, Combination; D017889:Exfoliation Syndrome / Q000150:complications*; D005260:Female; D005901:Glaucoma / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D006988:Hyphema / Q000209:etiology*; D000077338:Latanoprost; D011433:Propranolol / Q000627:therapeutic use; D011461:Prostaglandins F, Synthetic / Q000627:therapeutic use; D011680:Pupil; D014859:Warfarin / Q000627:therapeutic use*
D000925:Anticoagulants; D011461:Prostaglandins F, Synthetic; D014859:Warfarin; D000077338:Latanoprost; D002217:Carbachol; D011433:Propranolol