title: RADHA--a new male germ line-specific chromosomal protein of Drosophila.
abstract: A new chromosomal protein - RADHA - of Drosophila is described that is specific for the male germ line. It is encoded by a single-copy gene, located in the region 96C-D of D. melanogaster polytene chromosomes. Transcription of the radha gene is restricted to the primary spermatocyte stage. The protein initially accumulates in some of the Y-chromosomal lampbrush loops. After meiosis it is found in the nuclei of spermatids and might be involved in chromatin rearrangement processes in the male germ line. RADHA is a basic protein with a C-terminal leucine zipper region and several segments capable of forming coiled-coil structures.
authors.affiliation: Department of Physiological Chemistry and Pathobiochemistry, Johannes-Gutenberg University, Duesbergweg 6, D-55099 Mainz, Germany.
authors.forename: H R
authors.initials: HR
authors.lastname: Harhangi
authors.forename: X
authors.initials: X
authors.lastname: Sun
authors.forename: Y X
authors.initials: YX
authors.lastname: Wang
authors.forename: A
authors.initials: A
authors.lastname: Akhmanova
authors.forename: K
authors.initials: K
authors.lastname: Miedema
authors.forename: C
authors.initials: C
authors.lastname: Heyting
authors.forename: W
authors.initials: W
authors.lastname: Hennig
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004247:DNA; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000235:genetics*; D019476:Insect Proteins / Q000235:genetics*; D008297:Male; D008969:Molecular Sequence Data; D013090:Spermatocytes / Q000378:metabolism*; D013737:Testis / Q000166:cytology / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D029721:Drosophila Proteins; D019476:Insect Proteins; C121780:RHA protein, Drosophila; D004247:DNA