title: Protein folding in a specialized compartment: the endoplasmic reticulum.
abstract: The endoplasmic reticulum ensures proper folding of secretory proteins. In this review, we summarize and discuss the functions of different classes of folding mediators in the secretory pathway and propose updated models of the quality control system.
authors.affiliation: Department of Anatomy and Cell Biology, McGill University, Montreal, Quebec, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Zapun
authors.forename: C A
authors.initials: CA
authors.lastname: Jakob
authors.forename: D Y
authors.initials: DY
authors.lastname: Thomas
authors.forename: J J
authors.initials: JJ
authors.lastname: Bergeron
mesh_terms: D000818:Animals; D002451:Cell Compartmentation; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D006023:Glycoproteins / Q000378:metabolism; D037102:Lectins / Q000378:metabolism; D019696:Peptidylprolyl Isomerase / Q000378:metabolism; D019704:Protein Disulfide-Isomerases / Q000378:metabolism; D017510:Protein Folding
chemical_list: D006023:Glycoproteins; D037102:Lectins; D019696:Peptidylprolyl Isomerase; D019704:Protein Disulfide-Isomerases