title: Neurofibromatosis type 1: the role of neuroradiology.
abstract: Neurofibromatosis type 1 is the commonest of the phakomatoses with a prevalence of 1 in 3-4000. In common with most of the other phakomatoses it is a genetic disorder with typical dermatological manifestations. Many organ systems can be affected but brain, spine, cranial nerve and peripheral nerve involvement is frequent. In this review we will describe the central nervous system manifestations of neurofibromatosis type 1 and discuss some of the controversies raised by investigating children with this disorder.
authors.affiliation: Academic Department of Radiology, University of Sheffield, UK.
authors.forename: W
authors.initials: W
authors.lastname: Mukonoweshuro
authors.forename: P D
authors.initials: PD
authors.lastname: Griffiths
authors.forename: S
authors.initials: S
authors.lastname: Blaser
mesh_terms: D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D005910:Glioma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009456:Neurofibromatosis 1 / Q000175:diagnosis* / Q000473:pathology; D009900:Optic Nerve / Q000473:pathology; D019574:Optic Nerve Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed