The surgical treatment of adrenal gland tumors--incidentaloma.
Analysis of 32 patients operated on because of accidentally discovered adrenal tumors "incidentaloma" is presented. In 12 of them there was subclinical hormonal activity, in 9 of them tumors turned out to be pheochromocytoma and 3 of them were cortex adenoma. There were 20 hormonally inactive tumors, in 5 of them there were malignant lesions (4 of the cortex and 1 of the medulla). For evaluation of hormonal activity of adrenal tumors evaluation of chromogranin A and cortisol serum blood level or urine free cortisol level is recommended. For precise localization of the tumor beside USG also CT examination is of use. According to the high percentage of malignant lesions in "incidentaloma" type tumors, surgery treatment without delay is recommended. BAC or DHES in blood serum examinations were not found helpful in preoperative evaluating the lesions as benign or malignant. In case of preoperatively found subclinical hormonal hyperactivity of medulla pharmacological treatment with alpha and beta blockers in surgery preparation is recommended. Lateral extraperitoneal access for adrenalectomy is considered safe and provides good operational view. Laparoscopic procedure because of high percentage of malignant lesions in this group of patients is not justified.
Kolomecki
K
K
Department of Endocrinological and General Surgery, Medical University of Lodz, Copernicus Hospital, Poland.
Pomorski
L
L
Kuzdak
K
K
Narebski
J
J
Wichman
R
R
D000236:Adenoma / Q000097:blood / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000097:blood / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D000368:Aged; D002648:Child; D053379:Chromogranin A; D002864:Chromogranins / Q000097:blood; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D010673:Pheochromocytoma / Q000097:blood / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D014642:Vanilmandelic Acid / Q000652:urine
D053379:Chromogranin A; D002864:Chromogranins; D014642:Vanilmandelic Acid; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone