Effect of methodology on the tuberculocidal activity of a glutaraldehyde-based disinfectant.
Although official guidelines recommend a plate counting method for testing the susceptibility of mycobacteria to disinfectants, manufacturers usually prefer to employ the BACTEC procedure. Data showing that the BACTEC method overestimates the activity of a glutaraldehyde-based disinfectant against Mycobacterium tuberculosis in comparison with a conventional plate counting procedure are presented.
Dauendorffer
J N
JN
Laboratoire de Bactériologie, Centre Hospitalier et Universitaire de Nancy, 54511 Vandoeuvre-les-Nancy, France.
Laurain
C
C
Weber
M
M
Dailloux
M
M
D001431:Bacteriological Techniques; D015169:Colony Count, Microbial; D004202:Disinfectants / Q000494:pharmacology*; D005374:Filtration / Q000379:methods; D005976:Glutaral / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D008851:Micropore Filters; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000254:growth & development*
D004202:Disinfectants; D005976:Glutaral