title: [The usefulness of Aspargin for supplementing potassium and magnesium in ethanol dependent patients].
abstract: Intoxication with many xenobiotics cause serious electrolyte abnormalities which require intravenous supplementation. In chronic and acute but not very severe intoxication an oral supplementation of ions can be sufficient. The aim of the study was to evaluate the usefulness of Aspargin for supplementation of potassium and magnesium in chronic alcoholics suffering from withdrawal syndrome. There were 46 study patients, dependent on ethanol treated at the Detoxification Unit of the Department of Clinical Toxicology in Krak w. A differently intensified symptoms of ethanol withdrawal syndrome were noted according to CIWA-A scale in all the patients. Concentration of potassium and magnesium was monitored through the hospitalisation. Except a basic treatment (fluid supplementation, benzodiazepines) also Aspargin (three times a 2 tablets per day) was administered to each of patient for 7 to 10 days. No respiratory, muscular and gastrointestinal symptoms due to hypopotassemia and hypomagnesemia have been noted while hospitalisation in any patient so it could be suspected, that oral supplementation with Aspargin was sufficient to keep these ions balanced. Administration of Aspargin was beneficial to patient and the treatment outcome.
authors.affiliation: Kliniki Toksykologii KMPiChS Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.
authors.forename: J
authors.initials: J
authors.lastname: Pach
authors.forename: D
authors.initials: D
authors.lastname: Targosz
authors.forename: A
authors.initials: A
authors.lastname: Kamenczak
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000437:Alcoholism / Q000150:complications*; D001216:Asparagine / Q000627:therapeutic use*; D001569:Benzodiazepines / Q000008:administration & dosage; D004338:Drug Combinations; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007008:Hypokalemia / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D008274:Magnesium / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D001569:Benzodiazepines; D001216:Asparagine; D008274:Magnesium; D011188:Potassium