Side effects of lithium treatment on collagenous tissues.
Structural alterations of collagen fibrils induced by treatment with lithium chloride at various doses and durations, are investigated. In addition, this article describes how computer analyses of electron-optical images from collagen fibrils can lead to information about the changes produced by lithium on the molecular architecture of the fibril.
Tzaphlidou
M
M
Laboratory of Medical Physics, Medical School University of Ioannina, Greece.
D000818:Animals; D018692:Antimanic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D003094:Collagen / Q000187:drug effects* / Q000648:ultrastructure*; D007274:Injections, Intraperitoneal; D018021:Lithium Chloride / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D051379:Mice; D008854:Microscopy, Electron; D012867:Skin / Q000187:drug effects / Q000473:pathology* / Q000648:ultrastructure
D018692:Antimanic Agents; D003094:Collagen; D018021:Lithium Chloride