Orthotopic liver transplantation in a patient with severe haemophilia A and with advanced liver cirrhosis.
A patient with severe haemophilia A underwent orthotopic liver transplantation because of changes correlated to end-stage liver cirrhosis due to hepatitis B, C and D infection. Replacement therapy was carried out for 4 days and the clinical course was uneventful. At the time of reporting the patient has a normal working life. FVIII plasma concentration is normal. The indirect hyperbilirubinaemia may be related to the Gilbert's anomaly of the donor.
Baudo
F
F
Haemostasis and Thrombosis Unit and Liver Transplantation Center, Niguarda Hospital, Milan, Italy. md9821@mclink.it
Caimi
T M
TM
Redaelli
R
R
De Cataldo
F
F
Somaini
G
G
Rondinara
G F
GF
Degasperi
A
A
Bellati
G
G
Belli
L S
LS
Ideo
G
G
Morfini
M
M
Longo
G
G
D000203:Activities of Daily Living; D000328:Adult; D005169:Factor VIII / Q000627:therapeutic use; D018067:Flaviviridae / Q000235:genetics; D005878:Gilbert Disease / Q000097:blood; D006467:Hemophilia A / Q000150:complications / Q000601:surgery* / Q000821:virology; D006525:Hepatitis, Viral, Human / Q000150:complications; D006801:Humans; D006932:Hyperbilirubinemia / Q000209:etiology; D008103:Liver Cirrhosis / Q000150:complications / Q000601:surgery* / Q000821:virology; D016031:Liver Transplantation; D008297:Male; D012367:RNA, Viral / Q000097:blood; D014937:Work
D012367:RNA, Viral; D005169:Factor VIII