Intraoral tumor of Chievitz in a child.
Juxtaoral organs known as organs of Chievitz are intramuscular embryonic structures found close to the angle of the mandible near the insertion of the pterygomandibular raphae. They are considered of neuroepithelial origin with no known function. We describe the first tumor of the organ of Chievitz which presented intraorally in a child. Immunohistochemically, the Chievitz nests showed positive reaction for vimentin, cytokeratins, and epithelial membrane antigen and ultrastructurally demonstrated cytoplasmic processes and intermediate filament bundles. These observations, together with light microscopic features, suggest that the epithelial nests of the organ of Chievitz are meningothelial rather than neuroepithelial.
Vadmal
M S
MS
Department of Laboratories, North Shore University Hospital, Manhasset, NY 11030, USA.
Rossi
M B
MB
Teichberg
S
S
Hajdu
S I
SI
D000951:Antigens, Neoplasm / Q000032:analysis; D002648:Child; D004847:Epithelial Cells / Q000737:chemistry / Q000473:pathology; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D009062:Mouth Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure
D000951:Antigens, Neoplasm