[Is left ventricular regional wall motion after CABG influenced by cardioplegic protection?].
This clinical study was conducted to determine whether different techniques of cardioplegic protection reflected left ventricular regional wall motion after CABG. A total of 43 patients with more than 90% stenosis of the LAD (seg 6 and/or 7) before CABG, who had patent grafts were allocated to two groups: namely, the crystalloid group, comprised of 23 patients given cold crystalloid cardioplegia and topical ice slush, and the blood group, comprised of 20 patients given tepid blood cardioplegia delivered intermittently antegrade. Each group was divided into two subgroups according to whether the left ventricular regional wall motion showed no change or deterioration after CABG. We also examined the relationship between the grading of the collateral artery before CABG and the postoperative ventricular regional wall motion. The number of patients who showed deterioration after CABG was higher in the crystalloid group than in the blood group (p = 0.008). Moreover, patients in the crystalloid group whose collateral artery had been graded as 0 before CABG tended to show deterioration of left ventricular local wall motion after CABG (p = 0.07). Whereas those patients in the blood group did not. In conclusion, the incidence of deterioration after CABG was higher in the crystalloid group than in the blood group.
Shirasawa
B
B
First Department of Surgery, Yamaguchi University School of Medicine, Ube, Japan.
Hamano
K
K
Ikeda
N
N
Hayashi
Y
Y
Kawamura
T
T
Gohra
H
H
Katoh
T
T
Fujimura
Y
Y
Zempo
N
N
Esato
K
K
D000368:Aged; D002314:Cardioplegic Solutions / Q000009:adverse effects / Q000494:pharmacology*; D003097:Collateral Circulation; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D011184:Postoperative Period; D016277:Ventricular Function, Left / Q000187:drug effects
D002314:Cardioplegic Solutions