Genetic Analysis in Fine-needle Aspiration of the Thyroid: A New Tool for the Clinic.
This review will examine the application of genetic analysis to cytological specimens obtained by fine-needle aspiration biopsy in the management of thyroid tumours. In particular, it will consider the use of polymerase chain reaction-based techniques in the diagnosis of the micrometastasis of differentiated thyroid carcinoma to cervical lymph nodes, as well as in the detection of oncogenic alterations in solid thyroid nodules.
Russo
D
Cattedra di Farmacologia, Facoltá di Farmacia, Universitá di Catanzaro, Catanzaro, Italy.
Arturi
F
Pontecorvi
A
Filetti
S