title: The 14-3-3 proteins: cellular regulators of plant metabolism.
abstract: Signal transduction and enzyme regulation are known to occur via phosphorylation, but it is becoming increasingly apparent that phosphorylation might be only a necessary preamble to regulation. In many cases, the phosphorylated target protein must associate with a specialized adapter protein, known as 14-3-3, to complete the regulatory action. There are several prominent examples of 14-3-3 participation in plant regulatory events, including the regulation of plasma membrane H+-ATPase, nitrate reductase and sucrose phosphate synthase. However, emerging data on 14-3-3s in the nucleus might extend the roles for 14-3-3s well beyond the regulation of cytoplasmic enzymes.
authors.affiliation: Program in Plant Molecular and Cellular Biology, Dept of Horticultural Sciences, University of Florida, Gainesville, FL 32611, USA.
authors.initials: HJ
authors.lastname: Chung
authors.initials: PC
authors.lastname: Sehnke
authors.initials: RJ
authors.lastname: Ferl