Pseudophakic cystoid macular edema treated with high-dose intravenous methylprednisolone.
OBJECTIVE
To evaluate the efficacy of high-dose methylprednisolone in the treatment of pseudophakic cystoid macular edema (CME).


METHODS
University-affiliated hospital.


METHODS
Four patients with pseudophakic CME who reported decreased visual acuities were treated with oral prednisolone (20 mg daily for 5 days), oral acetazolamide (500 mg daily for 5 days), and topical dexamethasone 0.1% and diclofenac 0.1% (4 times a day for 14 days). The CME did not resolve. Next, they were treated with high-dose (1000 mg daily) intravenous methylprednisolone for 3 days.


RESULTS
In 3 of 4 eyes, the CME resolved and visual acuity improved.


CONCLUSIONS
High-dose methylprednisolone may be effective in the treatment of pseudophakic CME.
Abe
T
T
Department of Ophthalmology, Toyama Medical and Pharmaceutical University, Japan.
Hayasaka
S
S
Nagaki
Y
Y
Kadoi
C
C
Matsumoto
M
M
Hayasaka
Y
Y
D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction / Q000009:adverse effects; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007262:Infusions, Intravenous; D008269:Macular Edema / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D019591:Pseudophakia / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D014792:Visual Acuity / Q000187:drug effects
D005938:Glucocorticoids; D008775:Methylprednisolone