title: Comparison of flash lamp pulsed-dye laser (585 nm) and conventional surgery in the delay of random dorsal rat flaps.
abstract: OBJECTIVE
  Delay is a basic surgical technique used by flap surgeons to improve the blood supply to the distal parts of a random skin flap. The aim of this study was to determine whether a scarless delay can be done by the use of the flash lamp pulsed-dye laser operating at a wavelength of 585 nm.
  
  
  METHODS
  The pilot study showed that 6 J/cm(2) had a selective photothermolysis effect and therefore was chosen for testing the delay procedure on 15 rats. The percentage of flap necrosis of this group was compared to the results of 15 rats that underwent delay by surgery and 15 rats that were not treated prior to flap surgery (control group).
  
  
  RESULTS
  Laser delay of McFarlane flaps resulted in an average of 15.5% smaller necrotic area compared to the control group (52.7% +/- 14.4% and 68.2% +/- 9.6%, respectively, P < 0.01) and was as effective as surgical delay (53.3% +/- 13.6%).
  
  
  CONCLUSIONS
  The results indicate that the flash lamp pulsed-dye laser operating at 585 nm is effective for delaying cutaneous flaps in the rat model.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Tel-Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel-Aviv 64239, Israel. drcohen@netvision.net.il
authors.forename: M
authors.initials: M
authors.lastname: Cohen
authors.forename: A
authors.initials: A
authors.lastname: Kattan
authors.forename: A
authors.initials: A
authors.lastname: Gat
authors.forename: N
authors.initials: N
authors.lastname: Almogi
authors.forename: A
authors.initials: A
authors.lastname: Katzir
authors.forename: A
authors.initials: A
authors.lastname: Villan
authors.forename: E
authors.initials: E
authors.lastname: Gur
authors.forename: R
authors.initials: R
authors.lastname: Shafir
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D017075:Laser Coagulation / Q000009:adverse effects / Q000379:methods*; D008297:Male; D009336:Necrosis; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000528:radiation effects; D013524:Surgical Flaps / Q000098:blood supply* / Q000473:pathology