title: Sagittal sinus thrombosis associated with thrombocytopenia: a report of two patients.
abstract: Reported are two patients presenting with both thrombocytopenia and sagittal sinus thrombosis. The first patient is a 42-month-old male with no identified thrombophilic risk factors who developed acute neurologic symptoms after an acute infection. The second patient is a 22-month-old female with no history of preceding infection but had a positive lupus anticoagulant test. She also developed deep venous thrombosis and was treated with intravenous heparin. Both patients are currently doing well without neurologic deficits. To the authors' knowledge the second patient is the youngest reported patient with cerebral vein thrombosis associated with thrombocytopenia and lupus anticoagulant. These observations call attention to the need for a thorough investigation of thrombophilic risk factors in pediatric patients with thrombotic complications.
authors.affiliation: Department of Pediatric Neurology, Marmara University School of Medicine, Istanbul, Turkey.
authors.forename: G
authors.initials: G
authors.lastname: Alper
authors.forename: S G
authors.initials: SG
authors.lastname: Berrak
authors.forename: G
authors.initials: G
authors.lastname: Ekinci
authors.forename: C
authors.initials: C
authors.lastname: Canpolat
authors.forename: C
authors.initials: C
authors.lastname: Erzen
mesh_terms: D001921:Brain / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000209:etiology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D016682:Lupus Coagulation Inhibitor / Q000097:blood; D008297:Male; D012307:Risk Factors; D012851:Sinus Thrombosis, Intracranial / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D013921:Thrombocytopenia / Q000150:complications*; D020246:Venous Thrombosis / Q000209:etiology
chemical_list: D016682:Lupus Coagulation Inhibitor