Pemphigus and bullous pemphigoid.
Pemphigus and bullous pemphigoid are distinct autoimmune blistering diseases that are characterised by the presence of autoantibodies directed against specific adhesion molecules of the skin and mucous membranes. The comparison and contrast of molecular mechanism of blister formation of these two diseases provide a rational diagnostic and therapeutic approach to affected patients.
Nousari
H C
HC
Department of Dermatology, Johns Hopkins Medical Institutions, Baltimore, MD 21205-2196, USA. hnousar@jhmi.edu
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GJ
D001323:Autoantibodies / Q000032:analysis; D006801:Humans; D010257:Paraneoplastic Syndromes / Q000175:diagnosis; D010391:Pemphigoid, Bullous / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000628:therapy; D010392:Pemphigus / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000628:therapy
D001323:Autoantibodies