title: Major depression in the transition to adulthood: risks and impairments.
abstract: An ongoing longitudinal community study (N = 375) examined childhood risks and later adult impairments associated with 1-year Diagnostic and Statistical Manual of Mental Disorders (3rd ed., rev.; American Psychiatric Association, 1987) diagnoses of major depression during the transition to adulthood. Risks from birth to age 9 were reported by mothers, participants, and teachers. Teacher-reported hostility at age 6 predicted later depression. At age 9, self-perceptions of anxiety/depression, unpopularity, familial rejection, and abuse were potent risks. For men, neonatal and childhood health problems predicted later depression. For women, risks included family constellation, parental death, and poor academic achievement at age 9. Men and women who were depressed at age 18, age 21, or both demonstrated extensive psychosocial impairments in early adulthood, including poor overall functioning, interpersonal and behavioral problems, low self-esteem, and suicidality.
authors.affiliation: Young Adult Research Project, School of Social Work, Simmons College, Boston, Massachusetts 02116-2307, USA. hreinherz@simmons.edu
authors.forename: H Z
authors.initials: HZ
authors.lastname: Reinherz
authors.forename: R M
authors.initials: RM
authors.lastname: Giaconia
authors.forename: A M
authors.initials: AM
authors.lastname: Hauf
authors.forename: M S
authors.initials: MS
authors.lastname: Wasserman
authors.forename: A B
authors.initials: AB
authors.lastname: Silverman
mesh_terms: D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007398:Interpersonal Relations; D008137:Longitudinal Studies; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D012649:Self Concept; D012720:Severity of Illness Index