A One-Pot, One-Operation
Enantiomerically pure 2,1-benzothiazines are readily prepared by a one-pot, one-operation procedure consisting of a palladium-catalyzed aryl amination of an ortho-bromobenzaldehyde with a sulfoximine followed by an intramolecular condensation reaction [Eq. (1)]. BINAP=1,1'-binaphthalene-2,2'-diylbis(diphenylphosphane).
Harmata
M
Department of Chemistry, University of Missouri-Columbia, Columbia, MO 65211 (USA).
Pavri
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