Corneal endothelial changes in patients with chronic renal failure.
OBJECTIVE
To evaluate the morphologic changes of the corneal endothelium in patients with chronic renal failure.


METHODS
Twenty corneas of 20 patients with chronic renal failure undergoing hemodialysis were examined by wide-field specular microscopy. Twenty normal corneas from 20 healthy age-matched subjects were enrolled as control corneas.


RESULTS
Despite normal endothelial cell density, the corneal endothelium of patients with chronic renal failure showed marked polymegethism and pleomorphism.


CONCLUSIONS
Polymegethism and pleomorphism of the corneal endothelium are found in patients with chronic renal failure.
Ohguro
N
N
Department of Ophthalmology, Osaka University Medical School, Suita, Japan. nohguro@ophthal.med.osaka-u.ac.jp
Matsuda
M
M
Fukuda
M
M
D000293:Adolescent; D000328:Adult; D002452:Cell Count; D048429:Cell Size; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D006435:Renal Dialysis