[Changes in the L-serine and L-threonine dehydrogenase activities in the blood serum of those who worked in the cleanup of the aftermath of the accident at the Chernobyl Atomic Electric Power Station who became ill with chronic acalculous cholecystitis].
Activity was studied of blood serum plasmic enzymes L-serine and L-threonine dehydrogenazes (SDG and ThDG) in 92 liquidators of aftermath of the Chernobyl atomic power plant breakdown, presenting with chronic non-calculous cholecystitis during the stage of moderately severe exacerbation with no clinical and laboratory and sonographic signs of affection of the liver. A quarter of the examinees demonstrated an increased activity of the enzymes under study, which fact is regarded by the authors as a preclinical sign of reactive hepatitis. Recommendations are given as to the outpatient registration and prophylactic management and therapy of those persons having taken part in the elimination of the effects of the Chernobyl accident, presenting with biliary pathologies.
Komarenko
D I
DI
Soboleva
L P
LP
Ovsiannikova
L M
LM
Kadiuk
E N
EN
Shvaĭko
E A
EA
Nosach
E V
EV
D000328:Adult; D000429:Alcohol Oxidoreductases / Q000097:blood / Q000528:radiation effects*; D002764:Cholecystitis / Q000201:enzymology*; D002908:Chronic Disease; D006801:Humans; D012695:L-Serine Dehydratase / Q000097:blood / Q000528:radiation effects*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis; D011210:Power Plants; D018788:Radioactive Hazard Release; D013913:Threonine Dehydratase / Q000097:blood / Q000528:radiation effects*; D014455:Ukraine
D000429:Alcohol Oxidoreductases; C104535:NADP+-dependent serine dehydrogenase; C023159:L-threonine 3-dehydrogenase; D012695:L-Serine Dehydratase; D013913:Threonine Dehydratase