title: Pseudophakic cystoid macular edema treated with high-dose intravenous methylprednisolone.
abstract: OBJECTIVE
  To evaluate the efficacy of high-dose methylprednisolone in the treatment of pseudophakic cystoid macular edema (CME).
  
  
  METHODS
  University-affiliated hospital.
  
  
  METHODS
  Four patients with pseudophakic CME who reported decreased visual acuities were treated with oral prednisolone (20 mg daily for 5 days), oral acetazolamide (500 mg daily for 5 days), and topical dexamethasone 0.1% and diclofenac 0.1% (4 times a day for 14 days). The CME did not resolve. Next, they were treated with high-dose (1000 mg daily) intravenous methylprednisolone for 3 days.
  
  
  RESULTS
  In 3 of 4 eyes, the CME resolved and visual acuity improved.
  
  
  CONCLUSIONS
  High-dose methylprednisolone may be effective in the treatment of pseudophakic CME.
authors.affiliation: Department of Ophthalmology, Toyama Medical and Pharmaceutical University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Abe
authors.forename: S
authors.initials: S
authors.lastname: Hayasaka
authors.forename: Y
authors.initials: Y
authors.lastname: Nagaki
authors.forename: C
authors.initials: C
authors.lastname: Kadoi
authors.forename: M
authors.initials: M
authors.lastname: Matsumoto
authors.forename: Y
authors.initials: Y
authors.lastname: Hayasaka
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction / Q000009:adverse effects; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007262:Infusions, Intravenous; D008269:Macular Edema / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D019591:Pseudophakia / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D014792:Visual Acuity / Q000187:drug effects
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone