title: Combined field block and i.p. instillation of ropivacaine for pain management after laparoscopic sterilization.
abstract: We have studied the effect of ropivacaine for combined port site and mesosalpinx infiltration, and peritoneal instillation on pain, nausea and vomiting after laparoscopic sterilization, in a double-blind, placebo-controlled study in 80 patients. The total dose of ropivacaine was 285 mg. All patients received intra- and postoperative NSAID in fixed doses. Abdominal and shoulder pain, nausea and vomiting were recorded during the first 8 h after operation and in a diary for 3 days. In the ropivacaine group, abdominal pain scores were lower during the first 4 h (P < 0.00001), additional use of morphine was less (P < 0.001) and fewer patients had nausea or vomiting during the first 72 h (five vs 14; P < 0.05). There were no signs of local anaesthetic toxicity.
authors.affiliation: Department of Anaesthesiology, H:S Hvidovre University Hospital, Denmark.
authors.forename: T
authors.initials: T
authors.lastname: Callesen
authors.forename: D
authors.initials: D
authors.lastname: Hjort
authors.forename: T
authors.initials: T
authors.lastname: Mogensen
authors.forename: L
authors.initials: L
authors.lastname: Schouenborg
authors.forename: D
authors.initials: D
authors.lastname: Nielsen
authors.forename: H
authors.initials: H
authors.lastname: Reventlid
authors.forename: H
authors.initials: H
authors.lastname: Kehlet
mesh_terms: D000328:Adult; D000577:Amides / Q000627:therapeutic use*; D000768:Anesthesia, General; D000779:Anesthetics, Local / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D010535:Laparoscopy; D008875:Middle Aged; D009407:Nerve Block; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D020250:Postoperative Nausea and Vomiting / Q000517:prevention & control; D000077212:Ropivacaine; D013246:Sterilization, Tubal
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine