Perioperative hyperglycemia, infection or risk?
This review covers the recent studies that have served to further our understanding of the nature of the relationship between perioperative hyperglycemia and nosocomial infection. On the one hand hyperglycemia can be a consequence of the systemic inflammatory response, and can serve as a marker of the severity of stress and the degree of immunocompetence resulting from infection or injury. Strong evidence is, however, emerging that hyperglycemia in the perioperative period can also be a significant risk factor for the development of nosocomial infection.
Khaodhiar
L
L
Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
McCowen
K
K
Bistrian
B
B
D001786:Blood Glucose / Q000378:metabolism; D016638:Critical Illness; D003428:Cross Infection / Q000209:etiology*; D006706:Homeostasis; D006801:Humans; D006943:Hyperglycemia / Q000150:complications* / Q000628:therapy; D007430:Intraoperative Care / Q000379:methods*; D011183:Postoperative Complications / Q000517:prevention & control; D012307:Risk Factors
D001786:Blood Glucose