title: Destructive native valve endocarditis caused by Staphylococcus lugdunensis.
abstract: Coagulase-negative staphylococci are uncommon causes of native valve endocarditis, and the clinical course after valvular infection with these organisms is variable. In clinical practice, species identification is frequently not done, and possible differences in the pathogenicity of various species may be unrecognized. We report a case of Staphylococcus lugdunensis native valve endocarditis associated with valve leaflet perforation and cerebral embolization. This recently described species appears to be more virulent when infecting native cardiac valves than other species of coagulase-negative staphylococci. We review S lugdunensis native valve endocarditis.
authors.affiliation: Baylor College of Medicine, Department of Pathology, St. Luke's Episcopal Hospital, Texas Heart Institute, Houston, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: Burgert
authors.forename: M T
authors.initials: MT
authors.lastname: LaRocco
authors.forename: S
authors.initials: S
authors.lastname: Wilansky
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001021:Aortic Valve / Q000382:microbiology; D003030:Coagulase; D004697:Endocarditis, Bacterial / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D006349:Heart Valve Diseases / Q000382:microbiology* / Q000601:surgery; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000150:complications; D008297:Male; D013203:Staphylococcal Infections / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D013210:Staphylococcus / Q000145:classification* / Q000472:pathogenicity
chemical_list: D000900:Anti-Bacterial Agents; D003030:Coagulase