Corticosteroid-induced glaucoma attributable to an adrenocorticotropin-secreting malignant carcinoid tumor of the thymus.
OBJECTIVE
To describe the clinical and histopathologic findings in a patient with corticosteroid-induced open-angle glaucoma attributable to an adrenocorticotropin-secreting malignant carcinoid of the thymus.


METHODS
Case report. In a 33-year-old man, the clinical course, laboratory findings, and imaging results as well as the histopathologic findings are described.


RESULTS
Increased intraocular pressure in this patient represented a manifestation of severe hypercortisolism attributable to a malignant adrenocorticotropin-secreting carcinoid tumor. Surgical removal resulted in return of the intraocular pressure values to normal levels.


CONCLUSIONS
Thymic carcinoid is a rare cause of Cushing syndrome, which can lead to increased intraocular pressure.
Blumenthal
E Z
EZ
Department of Ophthalmology, Hadassah University Hospital and Hebrew University-Hadassah Medical School, Jerusalem, Israel. eblumenthal@hadassah.org.il
Muszkat
M
M
Pe'er
J
J
Ticho
U
U
D000308:Adrenocortical Hyperfunction / Q000150:complications* / Q000378:metabolism; D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000328:Adult; D002276:Carcinoid Tumor / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D005902:Glaucoma, Open-Angle / Q000209:etiology*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D013953:Thymus Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000601:surgery
D000324:Adrenocorticotropic Hormone