Intradialytic dobutamine therapy in maintenance hemodialysis patients with persistent hypotension.
Intradialysis hypotension is a common problem, especially in patients with poor left-ventricular function. We studied 6 patients who were on maintenance hemodialysis with left-ventricular ejection fraction of <40%, whose dialysis sessions were often complicated with severe hypotension (systolic blood pressure <90 mm Hg). Dobutamine infusion during dialysis significantly reduced the number of hypotensive episodes, increased left-ventricular ejection fraction, and decreased the number of emergency admissions to the hospital.
Anand
U
U
Divisions of Nephrology, Manipal Hospital, Bangalore, India.
Bastani
B
B
Dhanraj
P
P
Ballal
S H
SH
D000318:Adrenergic beta-Agonists / Q000008:administration & dosage / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D004280:Dobutamine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007022:Hypotension / Q000188:drug therapy* / Q000209:etiology; D007260:Infusion Pumps; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D016277:Ventricular Function, Left / Q000502:physiology
D000318:Adrenergic beta-Agonists; D004280:Dobutamine