title: [The treatment of cytomegalovirus retinitis in human immunodeficiency virus infection].
abstract: Most of the patients with immunodeficiency virus infection (75%-85%) are coinfected with cytomegalovirus. It is estimated that cytomegalovirus disease develops in 45% of them, mainly those presenting low CD4 cell counts (< 100/mm3). Retinitis is the most common manifestation of reactivated cytomegalovirus disease (85%), followed by other extra ocular sites (central nervous system, lungs, gastrointestinal system, adrenal glands, etc.). The particularly high incidence of cytomegalovirus retinitis, the difficulties concerning its therapeutical approach and the relatively unsatisfactory results, justify this review, according to the new treatment options presented in recent literature.
authors.affiliation: Departamento de Doenças Infecciosas, Hospitais da Universidade de Coimbra.
authors.forename: E
authors.initials: E
authors.lastname: Rabadão
authors.forename: V
authors.initials: V
authors.lastname: Duque
authors.forename: A
authors.initials: A
authors.lastname: Meliço-Silvestre
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy*; D019380:Anti-HIV Agents / Q000008:administration & dosage; D017726:Cytomegalovirus Retinitis / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D015497:HIV-1; D006801:Humans; D012074:Remission Induction; D013997:Time Factors
chemical_list: D019380:Anti-HIV Agents