Effect of ultraviolet light irradiation and nitrosoguanidine on viability of 46 strains of Arthrinium and their antibiotic production.
The ability of strains of the Arthrinium genus to inhibit microbial development has been previously described. In the present work different periods of mutagenic treatment using ultraviolet light, and of nitrosoguanidine treatment, on strains of Arthrinium were investigated. With nitrosoguanidine treatment the survival rate ranged from 2.17 to 8.78%. Mutant strains were only obtained with a higher antibiotic production in comparison with the wild-strain, when the mutagenic agent was UV light.
Calvo
M A
MA
Department of Pathology and Animal Production, Faculty of Veterinary Medicine, Universitat Autònoma de Barcelona, Spain.
Agut
M
M
Calvo
R M
RM
Larrondo
J
J
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D003904:Mitosporic Fungi / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism / Q000528:radiation effects*; D009604:Nitrosoguanidines / Q000494:pharmacology*; D014466:Ultraviolet Rays
D000900:Anti-Bacterial Agents; D009604:Nitrosoguanidines