A rare G2061 insertion affecting the open reading frame of CYP2D6 and responsible for the poor metabolizer phenotype.
Marez-Allorge
D
D
Laboratoire de Biochimie et Biologie Moléculaire, Hôpital Calmette, Centre Hospitalier Régional et Universitaire de Lille, France. marez@univ-lille2.fr
Ellis
S W
SW
Lo Guidice
J M
JM
Tucker
G T
GT
Broly
F
F
D001483:Base Sequence; D001711:Biotransformation; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D017931:DNA Primers; D006801:Humans; D016366:Open Reading Frames; D010641:Phenotype; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D018807:Polymorphism, Single-Stranded Conformational
D017931:DNA Primers; D019389:Cytochrome P-450 CYP2D6