Optimization of conductivity detection of low-molecular-mass anions in capillary zone electrophoresis.
The optimization of background electrolyte compositions for capillary zone electrophoresis in combination with conductivity detection focusing on maximal detector response is discussed. A theoretical approach pointing out the influence of the electrolyte co- and counter-ion mobilities on the detector signal has been developed. Using this model, running buffer compositions providing optimum S/N ratios for the selected analytes could be calculated. The results derived from these examinations have been verified by experimental investigations, namely the determination of inorganic and organic anionic solutes.
Katzmayr
M U
MU
Department of Analytical Chemistry, Johannes-Kepler-University Linz, Austria.
Klampfl
C W
CW
Buchberger
W
W
D000838:Anions / Q000032:analysis*; D002264:Carboxylic Acids / Q000032:analysis; D004553:Electric Conductivity; D004573:Electrolytes / Q000737:chemistry; D019075:Electrophoresis, Capillary / Q000379:methods*; D008956:Models, Chemical
D000838:Anions; D002264:Carboxylic Acids; D004573:Electrolytes