title: Sjögren's syndrome.
abstract: Sjögren's syndrome is a rather common autoimmune disease primarily characterized by the dysfunction and destruction of exocrine glands associated with lymphocytic infiltrations. The disorder has a quite broad clinical presentation, ranging from glandular disease to systemic involvement and to the development of lymphoid malignancy. This article reviews the current aspects in clinical diagnosis and management and the immunopathogenesis of the disorder.
authors.affiliation: Department of Pathophysiology, National University of Athens School of Medicine, Athens, Greece.
authors.forename: M N
authors.initials: MN
authors.lastname: Manoussakis
authors.forename: H M
authors.initials: HM
authors.lastname: Moutsopoulos
mesh_terms: D003937:Diagnosis, Differential; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D012140:Respiratory Tract Diseases / Q000175:diagnosis / Q000209:etiology; D012859:Sjogren's Syndrome / Q000175:diagnosis* / Q000209:etiology; D014570:Urologic Diseases / Q000175:diagnosis / Q000209:etiology; D014985:Xerophthalmia / Q000175:diagnosis / Q000209:etiology; D014987:Xerostomia / Q000175:diagnosis / Q000209:etiology