Omega-3 fatty acids and bipolar disorder: a review.
The important role of the omega-3 fatty acids in the pathophysiology and treatment of bipolar disorder is now supported by a substantial body of indirect and direct evidence. This paper will describe the clinical and pharmacological features of bipolar disorder, review the available data regarding omega-3 fatty acids in bipolar disorder and provide recommendations for future research.
Stoll
A L
AL
Psychopharmacology Research Laboratory, McLean Hospital, Belmont, MA 02478, USA.
Locke
C A
CA
Marangell
L B
LB
Severus
W E
WE
D000818:Animals; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000378:metabolism; D015525:Fatty Acids, Omega-3 / Q000378:metabolism / Q000627:therapeutic use*; D006801:Humans; D016032:Randomized Controlled Trials as Topic
D015525:Fatty Acids, Omega-3