Structure of the immediate early gene of canine herpesvirus.
The nucleotide sequence of the immediate early (IE) gene of canine herpesvirus was determined. This gene was located in the inverted repeat regions, encoding a polypeptide of 1,383 amino acids. The predicted amino acid sequence was most closely related to that of the feline herpesvirus 1 IE protein among those of other alphaherpesviruses. DNA binding and transcriptional activation domains were found in the IE protein. A spliced region of the IE gene transcript was determined in its 5' non-coding region.
Miyoshi
M
M
Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Takiguchi
M
M
Yasuda
J
J
Hashimoto
A
A
Takada
A
A
Okazaki
K
K
Kida
H
H
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics; D004285:Dogs; D017781:Genes, Immediate-Early / Q000235:genetics*; D016679:Genome, Viral; D002184:Herpesvirus 1, Canid / Q000737:chemistry / Q000235:genetics*; D017874:Immediate-Early Proteins / Q000235:genetics; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000235:genetics; D017422:Sequence Analysis, DNA
D004279:DNA, Viral; D017874:Immediate-Early Proteins; D012333:RNA, Messenger