title: Time-course effects of endurance training on fat oxidation in sedentary elderly people.
abstract: OBJECTIVE
  To investigate alterations in whole body fat oxidation after 7 and 14 weeks of progressive endurance training in sedentary elderly subjects.
  
  
  METHODS
  Longitudinal, 14 weeks of progressive endurance training on a cycle ergometer (3 training sessions per week). Full sets of measurements were performed before, and after 7 and 14 weeks of training.
  
  
  METHODS
  13 healthy sedentary subjects (5 men, 8 women) (age 62.8 +/- 2.3 y).
  
  
  METHODS
  24 h indirect calorimetric measurements under standardised conditions: light-activity programme, fixed food composition, neutral daily energy balance. Body composition (by isotope dilution and skinfold thicknesses). Maximal oxygen consumption.
  
  
  RESULTS
  Loss of 0.7 kg fat mass in the first 7 weeks of training and a further 2.4 kg of fat in the second 7 weeks. There was a transient increase in sleeping fat oxidation after 7 weeks of training (+26.1%), associated with transient increase in daily fat oxidation (+/- 11.9%), but fat oxidation then returned to baseline values in the second 7 weeks. There was a correlation between within-subject changes in sleeping fat oxidation after 7 weeks of training and variations in FFM (r = 0.62, P = 0.02) and maximal oxygen consumption (r = -0.56, P < 0.05).
  
  
  CONCLUSIONS
  In sedentary elderly subjects, progressive endurance training was associated with a transient increase in sleeping fat oxidation and daily fat oxidation. In free-living conditions, possible changes in daily fat oxidation may have induced a negative fat balance, as judged by fat mass loss.
authors.affiliation: Centre de Recherche en Nutrition Humaine d'Auvergne, Université d'Auvergne, Laboratoire de Nutrition Humaine, Clermont-Ferrand, France.
authors.forename: B
authors.initials: B
authors.lastname: Morio
authors.forename: C
authors.initials: C
authors.lastname: Montaurier
authors.forename: P
authors.initials: P
authors.lastname: Ritz
authors.forename: N
authors.initials: N
authors.lastname: Fellmann
authors.forename: J
authors.initials: J
authors.lastname: Coudert
authors.forename: B
authors.initials: B
authors.lastname: Beaufrère
authors.forename: M
authors.initials: M
authors.lastname: Vermorel
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D000368:Aged; D015444:Exercise / Q000502:physiology*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D008875:Middle Aged; D009584:Nitrogen / Q000652:urine; D010084:Oxidation-Reduction; D010101:Oxygen Consumption; D010807:Physical Endurance / Q000502:physiology*; D012890:Sleep / Q000502:physiology; D013997:Time Factors; D015431:Weight Loss
chemical_list: D005230:Fatty Acids, Nonesterified; D007328:Insulin; D009584:Nitrogen