Prenatal confirmation of the translocation between chromosome 15 and Y-chromosome by fluorescence in situ hybridization.
A 30-year-old woman and her husband visited our hospital with habitual abortion as the complaint. Chromosome examination revealed a normal 46, XX for her and 46, XY, 15, der (15) t (Y; 15) (q12; p12) for him. After her pregnancy amniocentesis was performed. The karyotype was 46, XX, 15, der (15) t (Y; 15) (q12; p12) pat. ish der (15) (DYZ1+). A female baby was delivered. The growth of the baby was normal at 12 months of age.
Fukada
Y
Y
Department of Obstetrics and Gynecology, Yamanashi Medical University, Nakakoma-gun, Japan. yfukada@res.yamanashi-med.ac.jp
Yasumizu
T
T
Amemiya
A
A
Kohno
K
K
Takizawa
M
M
Hoshi
K
K
D000026:Abortion, Habitual / Q000235:genetics; D000649:Amniocentesis; D002884:Chromosomes, Human, Pair 15; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007231:Infant, Newborn; D007743:Labor, Obstetric; D011247:Pregnancy; D014178:Translocation, Genetic; D014998:Y Chromosome