title: Antihistamines in the management of allergic pruritus in dogs and cats.
abstract: Antihistamines clearly have a place in the management of pruritus in the atopic dog and cat and, in this paper, important aspects of pharmacology and pharmacokinetics, adverse effects and precautions, and clinical use of these compounds are reviewed. Successful use of antihistamines is dependent on, among other considerations, the adherence to recommended doses and frequencies of administration, the recognition and control of concurrent and secondary factors, the willingness to try several different compounds, and the realisation that these agents are best employed in a preventive fashion.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.
authors.forename: D W
authors.initials: DW
authors.lastname: Scott
authors.forename: W H
authors.initials: WH
authors.lastname: Miller
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy* / Q000276:immunology; D002415:Cats; D004283:Dog Diseases / Q000188:drug therapy* / Q000276:immunology; D004285:Dogs; D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D006969:Hypersensitivity, Immediate / Q000188:drug therapy / Q000662:veterinary*; D011537:Pruritus / Q000188:drug therapy / Q000662:veterinary*; D014730:Veterinary Medicine / Q000592:standards
chemical_list: D006634:Histamine H1 Antagonists