title: A study testing the routine use of ultrasound measurements when selecting the electron energy for breast boost radiotherapy.
abstract: The determination of the depth of the tumour bed within the breast requiring an electron therapy boost dose is generally judged clinically and can be inconsistent between individual radiotherapists. High frequency ultrasound provides a reproducible, safe and quick method of measuring this depth. In order to improve current working practice at the Royal Marsden NHS Trust the routine use of ultrasound when planning breast boost radiotherapy was established. Fifty-three early stage postoperative breast cancer patients had both clinical and ultrasound assessments of boost depth performed. These measurements were converted into electron energy and compared. Measurements ranged from 0.8 cm to 4.9 cm and electron energy from 4 MeV to 15 MeV. As a direct result of the ultrasound measurements taken, 60% of patients had their electron energy changed from that chosen by the clinically assessed measurement. Overall, the energy was as likely to be increased as decreased. Breast size did not influence the need for change but patients with small breasts never required an increase in the energy from that chosen clinically. It was concluded that the use of ultrasound, once integrated into the planning process, can improve accuracy when selecting electron energy for patients receiving breast boost irradiation.
authors.affiliation: Royal Marsden NHS Trust and Institute of Cancer Research, Sutton, UK.
authors.forename: S J
authors.initials: SJ
authors.lastname: Helyer
authors.forename: E
authors.initials: E
authors.lastname: Moskovic
authors.forename: S
authors.initials: S
authors.lastname: Ashley
authors.forename: L
authors.initials: L
authors.lastname: Hastings
authors.forename: J R
authors.initials: JR
authors.lastname: Yarnold
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy*; D004583:Electrons / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness; D010347:Patient Care Planning; D011879:Radiotherapy Dosage; D012016:Reference Values; D016217:Ultrasonography, Mammary / Q000379:methods / Q000592:standards