title: Unravelling the kinetoplastid paraflagellar rod.
abstract: Researchers who study human pathogens are often interested in unique and essential aspects of the biology of the pathogen. Recent progress has been made in understanding such a target in kinetoplastid parasites. The paraflagellar rod is a unique cytoskeletal structure that plays a key role in the life-cycle of these fascinating organisms. This review discusses the protein components and structure of the paraflagellar rod and its function in cell motility.
authors.affiliation: Dept of Biochemistry, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Maga
authors.forename: J H
authors.initials: JH
authors.lastname: LeBowitz
mesh_terms: D000818:Animals; D005407:Flagella / Q000502:physiology* / Q000648:ultrastructure; D006801:Humans; D007891:Leishmania / Q000472:pathogenicity / Q000502:physiology* / Q000648:ultrastructure; D009068:Movement; D011506:Proteins; D015800:Protozoan Proteins / Q000502:physiology*; D014345:Trypanosoma / Q000472:pathogenicity / Q000502:physiology*
chemical_list: D011506:Proteins; D015800:Protozoan Proteins; C064816:kinetoplast-associated protein, protozoan