Sesquiterpene lactones from neurolaena oaxacana
Twelve sesquiterpene lactones, two new (1 and 2) and 10 known neurolenin-type germacranolides and furanoheliangolides (3-12) were isolated from Neurolaena oaxacana, and their structures were elucidated by NMR and GC-MS analysis. The chemotaxonomic importance of these findings is discussed. As N. lobata is used against dysenteries, neurolenin B (4) and a mixture of the neurolenins C (5) and D (6) were tested against Entamoeba histolytica and Giardia intestinalis.
Passreiter
CM
Institut fur Pharmazeutische Biologie, Heinrich-Heine-Universitat Dusseldorf, Universitatsstrasse 1, D-40225 Dusseldorf, Germany, Facultad de Ciencias Quimicas, Benemerita Universidad Autonoma de Puebla, Puebla, Mexico, Postgraduate Studies i.
Sandoval-Ramirez
J
Wright
CW