Transcription factors in hematopoiesis.
The advent of gene targeting in the mouse has led to rapid advances in the identification of factors controlling gene expression that are essential for normal hematopoietic development. Recent work has also uncovered roles for some of these factors in leukemogenesis and in the global regulation of chromatin structure.
Engel
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I
Department of Biology University of California at San Diego La Jolla, California, 92093-0366, USA. iengel@biomail.ucsd.edu.
Murre
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C
D000818:Animals; D019070:Cell Lineage; D002843:Chromatin / Q000502:physiology; D006410:Hematopoiesis / Q000502:physiology*; D007694:Killer Cells, Natural / Q000166:cytology; D051379:Mice; D013601:T-Lymphocytes / Q000166:cytology; D014157:Transcription Factors / Q000502:physiology*
D002843:Chromatin; D014157:Transcription Factors