Positron emission tomography in cochlear implant and auditory brain stem implant recipients.
OBJECTIVE
The purpose of this study was to determine whether similar cortical regions are activated by speech signals in profoundly deaf patients who have received a multichannel cochlear implant (CI) or auditory brain stem implant (ABI) as in normal-hearing subjects.


METHODS
Positron emission tomography (PET) studies were performed using a variety of discrete stimulus conditions. Images obtained were superimposed on standard anatomic magnetic resonance imaging (MRI) for the CI subjects. The PET images were superimposed on the ABI subject's own MRI.


METHODS
Academic, tertiary referral center.


METHODS
Five subjects who have received a multichannel CI and one who had received an ABI.


METHODS
Multichannel CI and ABI.


METHODS
PET images.


RESULTS
Similar cortical regions are activated by speech stimuli in subjects who have received an auditory prosthesis.


CONCLUSIONS
Neuroimaging provides a new approach to the study of speech processing in CI and ABI subjects.
Miyamoto
R T
RT
Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis 46202, USA.
Wong
D
D
Pisoni
D B
DB
Hutchins
G
G
Sehgal
M
M
Fain
R
R
D000161:Acoustic Stimulation; D000328:Adult; D001303:Auditory Cortex / Q000601:surgery*; D001933:Brain Stem / Q000601:surgery*; D016022:Case-Control Studies; D003054:Cochlear Implants; D003638:Deafness / Q000000981:diagnostic imaging* / Q000601:surgery*; D004567:Electrodes, Implanted; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013067:Speech Perception; D014055:Tomography, Emission-Computed