In vitro susceptibilities of Mycoplasma hominis to six fluoroquinolones as determined by E test.
Twenty isolates of Mycoplasma hominis were tested for their susceptibility to six fluoroquinolones by the E test. The MICs at which 90% of the isolates were inhibited (in micrograms per milliliter) were as follows: sparfloxacin, 0.031; clinafloxacin, moxifloxacin, and trovafloxacin, 0.063; levofloxacin, 0.25; and ciprofloxacin, 0.5. Increasing the amount of inoculum or incubation in CO(2) elevated MICs by </=1 dilution. E tests produce fluoroquinolone MICs comparable to those obtained by agar and microbroth dilution for M. hominis.
Waites
K B
KB
Departments of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA. waites@path.uab.edu
Canupp
K C
KC
Kenny
G E
GE
D000890:Anti-Infective Agents / Q000494:pharmacology*; D005069:Evaluation Studies as Topic; D024841:Fluoroquinolones; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods*; D019535:Mycoplasma hominis / Q000187:drug effects*
D000890:Anti-Infective Agents; D024841:Fluoroquinolones