title: Prevalence of cholelithiasis: results of an epidemiologic investigation in Vidauban, southeast France. General Practitioner's Group of Vidauban.
abstract: Cholelithiasis leads to 80,000 cholecystectomies being performed every year in France, but its prevalence is still unknown. The aim of this study was to assess the prevalence and risk factors of cholelithiasis in a random population of 1027 women and 727 men over the age of 30 in a small town in the southeast of France. Detailed clinical history, dietary investigation, and gallbladder ultrasound were collected for each subject and assessed by univariate analysis. A regression model was used in the multivariate analysis to detect the relative risk of cholelithiasis. Cholelithiasis was found in 130 individuals (global prevalence 13.9%). The relative risk for lithiasis was higher in women compared to men (1.89). Age (P<0.0001) and body mass index (BMI) >25 (P = 0.013) were also significant risk factors. Neither pregnancy nor oral contraceptive use proved to be risk factors. Typical biliary colic pain was the only symptom significantly associated with cholelithiasis (P<0.0001). These results show that the prevalence of gallstones in France is similar to that in Denmark and Italy.
authors.affiliation: Department of Gastroenterology and Radiology, University of Nice, France.
authors.forename: F X
authors.initials: FX
authors.lastname: Caroli-Bosc
authors.forename: C
authors.initials: C
authors.lastname: Deveau
authors.forename: A
authors.initials: A
authors.lastname: Harris
authors.forename: B
authors.initials: B
authors.lastname: Delabre
authors.forename: E P
authors.initials: EP
authors.lastname: Peten
authors.forename: P
authors.initials: P
authors.lastname: Hastier
authors.forename: E
authors.initials: E
authors.lastname: Sgro
authors.forename: C
authors.initials: C
authors.lastname: Caroli-Bosc
authors.forename: M
authors.initials: M
authors.lastname: Stoia
authors.forename: J F
authors.initials: JF
authors.lastname: Demarquay
authors.forename: R
authors.initials: R
authors.lastname: Dumas
authors.forename: A
authors.initials: A
authors.lastname: Coussement
authors.forename: J P
authors.initials: JP
authors.lastname: Delmont
mesh_terms: D000328:Adult; D000818:Animals; D015992:Body Mass Index; D002763:Cholecystectomy / Q000706:statistics & numerical data; D002769:Cholelithiasis / Q000453:epidemiology* / Q000209:etiology / Q000601:surgery; D003276:Contraceptives, Oral / Q000009:adverse effects; D003431:Cross-Cultural Comparison; D003430:Cross-Sectional Studies; D005260:Female; D005602:France / Q000453:epidemiology; D006168:Guinea Pigs; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011247:Pregnancy; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D003276:Contraceptives, Oral