[Pharmacological properties and therapeutic profile of artichoke (Cynara scolymus L.)].
The results of several clinical investigations showed the efficacy and safety of artichoke extracts (Cynara scolymus L.) in the treatment of hepato-biliary dysfunction and digestive complaints, such as sensation of fullness, loss of appetite, nausea and abdominal pain. Moreover earlier findings on a lipidlowering and hepatoprotective effect may be confirmed. In-vitro and in-vivo it has been possible to evaluate the underlying pharmacological mechanisms. Flavonoids and caffeoylquinic acids are mainly responsible for the observed actions.
Wegener
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Dienstleistung Phytopharmaka, Rheda-Wiedenbrück. tankred.wegener@t-online.de
Fintelmann
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D019659:Asteraceae; D002756:Cholagogues and Choleretics / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004415:Dyspepsia / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D010936:Plant Extracts / Q000009:adverse effects / Q000627:therapeutic use*; D010946:Plants, Medicinal; D016896:Treatment Outcome
D002756:Cholagogues and Choleretics; D010936:Plant Extracts