title: Varicella complicated by group A streptococcal sepsis and osteonecrosis.
abstract: A 5-year-old boy presented with primary varicella zoster virus infection, group A streptococcal sepsis, toxic shock, and multisite osteonecrosis. An association between osteonecrosis and group A streptococcal sepsis has not been previously reported. Clinical recognition with supportive radiologic and pathologic findings are presented. Therapeutic guidelines are suggested.
authors.affiliation: Division of General Pediatrics, Childrens Hospital Los Angeles, CA 90027, USA.
authors.forename: D
authors.initials: D
authors.lastname: Kouwabunpat
authors.forename: J
authors.initials: J
authors.lastname: Hoffman
authors.forename: R
authors.initials: R
authors.lastname: Adler
mesh_terms: D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology* / Q000821:virology; D002644:Chickenpox / Q000382:microbiology*; D002675:Child, Preschool; D006801:Humans; D008297:Male; D010020:Osteonecrosis / Q000382:microbiology* / Q000601:surgery / Q000821:virology; D012772:Shock, Septic / Q000382:microbiology / Q000821:virology; D013290:Streptococcal Infections / Q000188:drug therapy / Q000821:virology*; D013297:Streptococcus pyogenes