title: A confrontational naming task produces congruent increases and decreases in PET and fMRI.
abstract: This work uses the well-established (by PET) confrontation naming task to compare PET and fMRI in a cognitive activation experiment. The signal changes from this task are much less than the changes caused by visual or motor activation tasks used in previous comparisons. ANOVA methods adjusted for multiple comparisons were used to determine significant changes in signal between confrontation naming and figure size discrimination tasks. All 17 significantly increased regions (confrontation naming signal greater) seen on one modality were increased on both modalities. Ten of 13 regions that were significantly decreased on one modality were decreased on the other. Three mismatched regions showed a significant decrease on one modality and a nonsignificant increase on the other. This study could not detect a consistent difference in activation site location between PET and fMRI.
authors.affiliation: Department of Radiology, Emory University, Atlanta, Georgia, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Votaw
authors.forename: T L
authors.initials: TL
authors.lastname: Faber
authors.forename: C A
authors.initials: CA
authors.lastname: Popp
authors.forename: T R
authors.initials: TR
authors.lastname: Henry
authors.forename: J D
authors.initials: JD
authors.lastname: Trudeau
authors.forename: J L
authors.initials: JL
authors.lastname: Woodard
authors.forename: H
authors.initials: H
authors.lastname: Mao
authors.forename: J M
authors.initials: JM
authors.lastname: Hoffman
authors.forename: A W
authors.initials: AW
authors.lastname: Song
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001921:Brain / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory; D011581:Psychological Tests; D014055:Tomography, Emission-Computed; D014706:Verbal Learning; D014888:Wechsler Scales