title: Red cell enzyme polymorphisms in Moroccans and southern Spaniards: new data for the genetic history of the western Mediterranean.
abstract: Population samples from Morocco (El Jadida, south Atlantic coast) and La Alpujarra (Granada mountains, Spain), located on both shores of the western Mediterranean, were typed for 8 erythrocyte genetic markers: ACP1, ESD, PGD, AK1, GLO1, PGM1, SODA, and DIA. Genetic heterogeneity within western Mediterranean groups was investigated on the basis of allele frequencies of these 8 polymorphisms plus ABO and Rh (CDE). Only slight peculiarities for the ACP1, GLO1, and AK1 systems were observed in the 2 samples compared with other Mediterranean data. The new data are consistent with a main north to south genetic differentiation in the Mediterranean region. However, with regard to other European groups, the La Alpujarra population shows a particular affinity with North Africans that may be compatible with both an ancient common substratum and/or a special historical influence during the Muslim domination of the Iberian Peninsula.
authors.affiliation: Département de Biologie, Faculté des Sciences, Université Chouaïb Doukkali, El Jadida, Morocco.
authors.forename: M
authors.initials: M
authors.lastname: Kandil
authors.forename: P
authors.initials: P
authors.lastname: Moral
authors.forename: E
authors.initials: E
authors.lastname: Esteban
authors.forename: L
authors.initials: L
authors.lastname: Autori
authors.forename: G E
authors.initials: GE
authors.lastname: Mameli
authors.forename: D
authors.initials: D
authors.lastname: Zaoui
authors.forename: C
authors.initials: C
authors.lastname: Calo
authors.forename: F
authors.initials: F
authors.lastname: Luna
authors.forename: L
authors.initials: L
authors.lastname: Vacca
authors.forename: G
authors.initials: G
authors.lastname: Vona
mesh_terms: D000328:Adult; D000483:Alleles; D004798:Enzymes / Q000235:genetics*; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D014644:Genetic Variation; D006801:Humans; D008297:Male; D019083:Mediterranean Region; D009018:Morocco; D010641:Phenotype; D011110:Polymorphism, Genetic; D012494:Sampling Studies; D013030:Spain
chemical_list: D004798:Enzymes; D005819:Genetic Markers