Neurologic complications associated with hepatitis C virus infection.
A series of nine patients with neurologic complications of hepatitis C virus infection is reported. Seven patients presented a combination of chronic sensory polyneuropathy, multineuropathy, and encephalopathy related to cryoglobulinemia. The noncryoglobulinemic symptoms consisted of an anterior optic neuropathy and a restless legs syndrome with small-fiber neuropathy. Corticosteroids and cyclophosphamide were useful in controlling vasculitic episodes. Interferon-alpha caused remission in half of the treated patients.
Tembl
J I
JI
Department of Neurology, Hospital Universitari La Fe, Valencia, Spain.
Ferrer
J M
JM
Sevilla
M T
MT
Lago
A
A
Mayordomo
F
F
Vilchez
J J
JJ
D000328:Adult; D000368:Aged; D004576:Electromyography; D005260:Female; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000150:complications / Q000473:pathology / Q000503:physiopathology / Q000628:therapy