Estrogens control aggressive behavior in some patients with Sanfilippo syndrome.
We report two women with Sanfilippo syndrome. Both had characteristic aggressiveness that was refractory to treatment with conventional agents. Both women improved on oral estrogen therapy and showed diminished aggressiveness.
Hier
D B
DB
Department of Neurology, University of Illinois at Chicago 60612-7330, USA.
Ahluwalie
S
S
Melyn
M
M
Hoganson
G E
GE
D000328:Adult; D000374:Aggression / Q000187:drug effects* / Q000523:psychology*; D004967:Estrogens / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D009084:Mucopolysaccharidosis III / Q000188:drug therapy* / Q000523:psychology*
D004967:Estrogens