title: SWEET - WWW-based rapid 3D construction of oligo- and polysaccharides.
abstract: SWEET is a WWW-based tool which rapidly converts the commonly used carbohydrate sequence information directly into a preliminary but reliable 3D model which can be visualised and written to files in several ways.
  
  
  BACKGROUND
  SWEET is accessible via the Internet at http://www.dkfz-heidelberg.de/spec/.
  
  
  BACKGROUND
  a. bohne@dkfz-heidelberg.de or w.vonderlieth@ dkfz-heidelberg.de
  
  
  BACKGROUND
  The current version of SWEET generates only one conformation out of a manifold. Several authors have analysed possible conformations of high-mannose N-linked glycans using a combination of NMR methods and computational approaches showing that such molecules are rather flexible populating normally several conformations for each glycosidic linkage. The displayed model exhibits for all glycosidic linkages a conformation which is in accordance with the reported variations of Phi, psi and omega values for specific linkage (see http://www.dkfz-heidelberg. de/spec/sweet2/doc/input/sba_example.html).
authors.affiliation: Deutsches Krebsforschungszentrum, Zentrale Spektroskopie, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Bohne
authors.forename: E
authors.initials: E
authors.lastname: Lang
authors.forename: C W
authors.initials: CW
authors.lastname: von der Lieth
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D020407:Internet; D009844:Oligosaccharides / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry*; D012984:Software
chemical_list: D009844:Oligosaccharides; D011134:Polysaccharides