title: Reversible neuropraxic visual loss induced by allergic Aspergillus flavus sinomycosis.
abstract: This work reports a patient with visual loss treated successfully with surgical removal of the Aspergillus flavus sinomycosis. Vision was partially reversed within hours after surgery before starting planned corticosteroid therapy. The patient's visual acuity continued to improve steadily until it became equal to that of the other eye. The immediate gain in vision and continued improvement without corticosteroid therapy suggest a new hypothesis for visual loss induced by allergic sinonasal Aspergillosis. Simple mechanical pressure alone of the aspergillus mass over the nerve can produce visual loss, and this loss is reversed by removing the mass without corticosteroid therapy.
authors.affiliation: King Abdulaziz University Hospital, Riyadh, Saudi Arabia.
authors.forename: M
authors.initials: M
authors.lastname: Attallah
authors.forename: M
authors.initials: M
authors.lastname: Hashash
authors.forename: H
authors.initials: H
authors.lastname: al-Muhaimeed
authors.forename: S
authors.initials: S
authors.lastname: Dousary
authors.forename: A
authors.initials: A
authors.lastname: al Rabah
authors.forename: S
authors.initials: S
authors.lastname: Kharashi
mesh_terms: D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000601:surgery*; D001231:Aspergillus flavus; D001766:Blindness / Q000382:microbiology* / Q000628:therapy; D004724:Endoscopy; D005005:Ethmoid Sinus / Q000601:surgery; D005500:Follow-Up Studies; D006261:Headache / Q000382:microbiology; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008443:Maxillary Sinus / Q000601:surgery; D015508:Nasal Obstruction / Q000382:microbiology; D009901:Optic Nerve Diseases / Q000382:microbiology* / Q000628:therapy; D012220:Rhinitis / Q000382:microbiology; D012852:Sinusitis / Q000382:microbiology* / Q000601:surgery; D013101:Sphenoid Sinus / Q000601:surgery; D014792:Visual Acuity
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole