Hemochromatosis associated with endothelial dysfunction: evidence for the role of iron stores in early atherogenesis.
Impaired endothelium-dependent, flow-mediated dilatation of the brachial artery was observed in a 50-year-old premenopausal female non-smoker with idiopathic hemochromatosis. Endothelial dysfunction observed in this patient supports a relationship between body iron stores and early atherosclerotic process.
Lekakis
J
J
Department of Clinical Therapeutics, Athens University, Alexandria Hospital, Athens, Greece.
Papamicheal
C
C
Stamatelopoulos
K
K
Cimponeriu
A
A
Voutsas
A
A
Vemmos
K
K
Mavrikakis
M
M
Stamatelopoulos
S
S
D001161:Arteriosclerosis / Q000209:etiology; D001916:Brachial Artery / Q000000981:diagnostic imaging / Q000502:physiology / Q000503:physiopathology; D004730:Endothelium, Vascular / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D005293:Ferritins / Q000097:blood; D006432:Hemochromatosis / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology*; D006801:Humans; D007501:Iron / Q000378:metabolism*; D008875:Middle Aged; D017697:Premenopause; D018608:Ultrasonography, Doppler; D014664:Vasodilation / Q000502:physiology
D005293:Ferritins; D007501:Iron