An Unprecedented Domino Double Allylsilane
A stereoselective synthesis of the disilyl derivatives 3 is achieved by the title reaction, an unprecedented Lewis acid promoted domino reaction, between the cross-conjugated dienone 1 and the allylsilanes 2. The configurations of the five stereogenic centers of this novel ring system are established in the first step of the reaction sequence, the double [3+2] cycloaddition.
Knölker
HJ
Institut für Organische Chemie der Universität, Richard-Willstätter-Allee, D-76131 Karlsruhe (Germany).
Baum
E
Graf
R
Jones
PG
Spieß
O