title: Giant cell tumor of bone.
abstract: Seventy-two cases of giant cell tumor (GCT) of bone were diagnosed in our clinic between 1986 and 1998. The mean age of the patients was 35 (range: 11 to 63 years) and the female to male ratio was 1.3:1. Fifty-four percent of the cases had involvement about the knee (distal femur, upper tibia, and upper fibula). Four patients had a malignant form of the disease and another four had the disease before closure of the physis. There was no case of multicentric involvement. Nine patients presented with pathological fracture. Forty-seven patients had histological grading done. Twenty three (49%) had grade I, 17 (36%) had grade II, and seven (15%) had grade III disease. The mean follow-up time was 59.6 months (range: 24 to 142 months) for patients at least two years follow-up. There was a 33% complication rate.
authors.affiliation: Ankara University School of Medicine, Turkey.
authors.forename: Y
authors.initials: Y
authors.lastname: Saglik
authors.forename: Y
authors.initials: Y
authors.lastname: Yildiz
authors.forename: A
authors.initials: A
authors.lastname: Karakas
authors.forename: H
authors.initials: H
authors.lastname: Ogüt
authors.forename: S
authors.initials: S
authors.lastname: Erekul
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery*; D018286:Carcinoma, Giant Cell / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery*; D003625:Data Collection; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D017678:Sex Distribution; D015996:Survival Rate; D014421:Turkey / Q000453:epidemiology