Acidocalcisome: A novel Ca2+ storage compartment in trypanosomatids and apicomplexan parasites.
Acidocalcisomes are novel acidic Ca2+ storage organelles found in trypanosomatids and apicomplexan parasites, abundant in the intracellular stages of these parasites, and characterized by their high electron density, and high content of phosphorus, Ca2+, Mg2+, Na+ and Zn2+. A number of energy-utilizing pumps and exchangers have been found in these organelles, which underlines their importance in the homeostasis of different elements, as discussed here by Roberto Docampo and Silvia Moreno.
Docampo
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Laboratory of Molecular Parasitology, Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, 2001 South Lincoln Avenue, Urbana, IL 61802, USA. rodoc@uiuc.edu
Moreno
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D000818:Animals; D016782:Apicomplexa / Q000737:chemistry / Q000378:metabolism* / Q000648:ultrastructure; D002118:Calcium / Q000032:analysis / Q000378:metabolism*; D008274:Magnesium / Q000032:analysis / Q000378:metabolism; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D015388:Organelles / Q000737:chemistry / Q000378:metabolism* / Q000648:ultrastructure; D011122:Polyphosphates / Q000737:chemistry; D012964:Sodium / Q000032:analysis / Q000378:metabolism; D014351:Trypanosomatina / Q000737:chemistry / Q000378:metabolism* / Q000648:ultrastructure; D015032:Zinc / Q000032:analysis / Q000378:metabolism
D011122:Polyphosphates; D012964:Sodium; D008274:Magnesium; D015032:Zinc; D002118:Calcium