title: [The clinical usefulness of routine biopsy of the transition zone in the diagnosis of prostate cancer].
abstract: OBJECTIVE
  To evaluate the effectiveness of routine biopsy of the transitional area in patients undergoing early systematic sextant biopsy.
  
  
  METHODS
  Two biopsies were taken from the transitional area further to a sextant biopsy in 164 consecutive patients. 98 cases had serum PSA levels higher than 4 ng/mL and 66 suspicious rectal digital examination.
  
  
  RESULTS
  Cancer was detected in 77 patients (46.9%). In 28 (36.4%) cases cancer was found only in the peripheral area, in 2 (2.6%) in the transitional area and in 47 (61%) in both areas.
  
  
  CONCLUSIONS
  Routine biopsy of the transitional area in early systematic prostate biopsy appears to be little effective. This would probably be indicated for patients undergoing rebiopsy.
authors.affiliation: Servicio de Urología, Hospital Vall d'Hebrón, Universidad Autónoma, Barcelona.
authors.forename: J
authors.initials: J
authors.lastname: Morote Robles
authors.forename: M
authors.initials: M
authors.lastname: López Pacios
authors.forename: G
authors.initials: G
authors.lastname: Encabo Duró
authors.forename: I
authors.initials: I
authors.lastname: de Torres Ramírez
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods / Q000706:statistics & numerical data; D003955:Diagnostic Tests, Routine / Q000379:methods / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000097:blood / Q000473:pathology*
chemical_list: D017430:Prostate-Specific Antigen