[A preclinical study of ximedone].
Pharmacotoxicological properties of ximedone, a new pyrimidine derivative, were studied experimentally on animals of various species. In the enteral regimen the drug had a favourable effect on thermal burns and postoperative cutaneous and gastric wounds. The results enabled to recommend ximedone for the clinical practice.
Izmaĭlov
S G
SG
Military Medical Institute, Nizhnyi Novgorod Medical Academy, Kazan State Medical University.
Gorbunov
S M
SM
Izmaĭlov
G A
GA
Zaikonnikova
I V
IV
Reznik
V S
VS
Abdrakhmanova
N G
NG
Pashkurov
N G
NG
Kedrin
M Iu
MIu
Gerasimova
M Kh
MKh
Garaev
V N
VN
Izmaĭlov
A G
AG
Podushkina
I V
IV
Evranova
G B
GB
Muslinkin
A A
AA
D000276:Adjuvants, Immunologic / Q000627:therapeutic use* / Q000633:toxicity; D000818:Animals; D002056:Burns / Q000188:drug therapy*; D004353:Drug Evaluation, Preclinical; D006168:Guinea Pigs; D007928:Lethal Dose 50; D051379:Mice; D011183:Postoperative Complications / Q000517:prevention & control; D011743:Pyrimidines / Q000627:therapeutic use* / Q000633:toxicity; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D013530:Surgical Wound Infection / Q000188:drug therapy*; D014945:Wound Healing / Q000187:drug effects
D000276:Adjuvants, Immunologic; D011743:Pyrimidines; C069705:xymedon