title: Measurement of iodine-123 thyroid uptake using a gamma camera with LEAP collimator.
abstract: OBJECTIVE
  This study compared the 123I thyroid uptake measurements obtained from a gamma camera fitted with a low-energy all-purpose (LEAP) collimator to those obtained from a thyroid uptake probe and gamma camera fitted with a pinhole (PH) collimator.
  
  
  METHODS
  Thirty-one patients (27 female and 4 male patients) were studied for comparison between a probe and a gamma camera fitted with LEAP collimators. A different group of 25 patients (20 female and 5 male patients) were studied for comparison between LEAP and PH collimators. The patients were given 7.4-11 MBq (200-300 pCi) 123I capsules orally. Uptake with both the probe and the gamma camera was measured at 5 h and 24 h. The uptake measurements by these 3 methods were compared.
  
  
  RESULTS
  Comparison of all the camera uptake values with the probe system correlated well with correlation coefficient values ranging from 0.912-0.988. The probe system yielded uptake ratios slightly higher than those measured by the gamma camera with LEAP collimator. Comparison between LEAP and PH uptake values resulted in a correlation coefficient of 0.979 for 5 h and 0.931 for 24 h uptake.
  
  
  CONCLUSIONS
  Iodine-123 uptake with a gamma camera fitted with a LEAP collimator can accurately and consistantly be used to determine the thyroid uptake of 123I if proper ROIs are applied.
authors.affiliation: Department of Medicine, College of Medicine and King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.
authors.forename: R S
authors.initials: RS
authors.lastname: Benjamin
authors.forename: A
authors.initials: A
authors.lastname: Amro
authors.forename: M I
authors.initials: MI
authors.lastname: El-Desouki
mesh_terms: D005260:Female; D015902:Gamma Cameras; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D011877:Radionuclide Imaging; D012588:Scintillation Counting / Q000295:instrumentation; D013961:Thyroid Gland / Q000000981:diagnostic imaging*
chemical_list: D007457:Iodine Radioisotopes