title: Pulmonary nocardiosis in a child with hyperimmunoglobulin E syndrome.
abstract: Hyperimmunoglobulin E syndrome (HIE) is a rare condition characterised by marked elevation of serum IgE level, chronic dermatitis, intense pruritus, and recurrent serious infection. The major organism is usually S aureus. We report a case of an infant with HIE, who had pulmonary nocardiosis. The clinical features, immunological abnormalities, and radiological features of the condition are described. The child finally succumbed to the complications of pulmonary nocardiosis.
authors.affiliation: Department of Paediatrics, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: W S
authors.initials: WS
authors.lastname: Lee
authors.forename: C C
authors.initials: CC
authors.lastname: Boey
authors.forename: A Y
authors.initials: AY
authors.lastname: Goh
mesh_terms: D003241:Consanguinity; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007223:Infant; D007589:Job Syndrome / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology; D018655:Lymphocyte Count; D016131:Lymphocyte Subsets / Q000276:immunology; D009617:Nocardia Infections / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology; D009894:Opportunistic Infections / Q000175:diagnosis / Q000235:genetics / Q000276:immunology; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology
chemical_list: D007073:Immunoglobulin E