title: Isoquinoline-6-carboxamides as potent and selective anti-human cytomegalovirus (HCMV) inhibitors.
abstract: Structure-activity relationship studies on our newly identified anti-HCMV compounds, the 1,6-naphthyridines led to the identification of isoquinoline-6-carboxamides as potent and selective anti-HCMV agents.
authors.affiliation: BioChem Pharma Inc., Québec Canada.
authors.forename: L
authors.initials: L
authors.lastname: Chan
authors.forename: H
authors.initials: H
authors.lastname: Jin
authors.forename: T
authors.initials: T
authors.lastname: Stefanac
authors.forename: W
authors.initials: W
authors.lastname: Wang
authors.forename: J F
authors.initials: JF
authors.lastname: Lavallée
authors.forename: J
authors.initials: J
authors.lastname: Bédard
authors.forename: S
authors.initials: S
authors.lastname: May
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology*; D003587:Cytomegalovirus / Q000187:drug effects*; D007546:Isoquinolines / Q000737:chemistry / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D013329:Structure-Activity Relationship
chemical_list: D000998:Antiviral Agents; D007546:Isoquinolines