Two mutations in the multidrug-resistance gene homologue of Plasmodium falciparum, pfmdr1, are not useful predictors of in-vivo or in-vitro chloroquine resistance in southern Africa.
McCutcheon
K R
KR
Parasitology Research Programme, University of the Witwatersrand, Johannesburg, South Africa. keir@gecko.biol.wits.ac.za
Freese
J A
JA
Frean
J A
JA
Sharp
B L
BL
Markus
M B
MB
D000353:Africa, Southern; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D002738:Chloroquine / Q000627:therapeutic use*; D005240:Feasibility Studies; D019450:Genes, MDR; D017125:Genes, Protozoan; D006801:Humans; D009154:Mutation; D010963:Plasmodium falciparum / Q000235:genetics*; D011110:Polymorphism, Genetic; D011237:Predictive Value of Tests
D000962:Antimalarials; D002738:Chloroquine