[Acquired factor VIII deficiency treated with cyclosporine].
The treatment of acquired factor VIII inhibitors remains controversial, and no standard therapy exists. We describe a case story of successful treatment with prednisolone and cyclosporine of an 83-year old female with severe bleeding disorder due to an acquired factor VIII inhibitor. The patient had complete remission, and no side effects were observed. We recommend that treatment of acquired factor VIII inhibitor with cyclosporine is further investigated.
Leinøe
E B
EB
Københavns Amts Trombosecenter.
Jørgensen
M
M
Nielsen
J D
JD
D000368:Aged; D001323:Autoantibodies / Q000032:analysis; D016572:Cyclosporine / Q000627:therapeutic use*; D005169:Factor VIII / Q000276:immunology*; D005260:Female; D006467:Hemophilia A / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*
D001323:Autoantibodies; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D005169:Factor VIII