title: Management strategies in unstable coronary artery disease--current problems and future directions. The UCAD Council.
abstract: Unstable coronary artery disease continues to pose a major challenge to clinicians. The advent of new therapies, such as percutaneous transluminal coronary angioplasty, low-molecular-weight heparins, and glycoprotein IIb/IIIa inhibitors, provides new management options for this indication but also raises new questions with regard to optimal management. Prospective randomized trials with well-defined, long-term outcome measures and a means of identifying which patients will derive most benefit from each treatment, together with a means of rapid and clear dissemination of study results and implications, are required in order to advance the management of unstable coronary artery disease.
authors.affiliation: Department of Cardiology, Academic Hospital Nijmegen St Radboud, The Netherlands.
authors.forename: F W
authors.initials: FW
authors.lastname: Verheugt
authors.forename: R C
authors.initials: RC
authors.lastname: Becker
authors.forename: M E
authors.initials: ME
authors.lastname: Bertrand
authors.forename: C
authors.initials: C
authors.lastname: Bode
authors.forename: J H
authors.initials: JH
authors.lastname: Chesebro
authors.forename: J G
authors.initials: JG
authors.lastname: Cleland
authors.forename: R
authors.initials: R
authors.lastname: Conti
authors.forename: W S
authors.initials: WS
authors.lastname: Hillis
authors.forename: W
authors.initials: W
authors.lastname: Klein
authors.forename: A
authors.initials: A
authors.lastname: Maseri
authors.forename: A G
authors.initials: AG
authors.lastname: Turpie
authors.forename: L
authors.initials: L
authors.lastname: Wallentin
authors.forename: D D
authors.initials: DD
authors.lastname: Waters
mesh_terms: D000789:Angina, Unstable / Q000628:therapy*; D015906:Angioplasty, Balloon, Coronary; D000925:Anticoagulants / Q000627:therapeutic use; D002309:Cardiology / Q000639:trends*; D002986:Clinical Trials as Topic; D003327:Coronary Disease / Q000628:therapy*; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; D019039:Platelet Glycoprotein GPIIb-IIIa Complex