title: Degenerative disc disease and back pain.
abstract: Although MR imaging has become the most accurate test for depicting abnormal morphology, there is no agreement on the diagnostic value of morphology alone. If the natural history of a disease is not clearly understood, and if there is little consensus, within or between specialties, regarding the use of diagnostic tests, the risk of misdiagnosis is high. Degenerative disc disease is costly, debilitating, and one of the most complex conditions to manage. This article discusses symptomatology, including instability and malalignment abnormalities, intervertebral disc degeneration or herniation, spinal stenosis, and facet disease, as treated in a variety of current studies; emphasis is placed on bridging the gaps between technology, areas that deserve further research, and sound clinical judgement.
authors.affiliation: Department of Radiology, Ohio State University College of Medicine, Columbus, USA.
authors.forename: M T
authors.initials: MT
authors.lastname: Modic
mesh_terms: D001416:Back Pain / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007403:Intervertebral Disc / Q000473:pathology*; D007405:Intervertebral Disc Displacement / Q000175:diagnosis / Q000628:therapy; D008159:Lumbar Vertebrae / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D013122:Spinal Diseases / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D013130:Spinal Stenosis / Q000175:diagnosis / Q000628:therapy