Transient elevation in plasma prolactin level in rats with temporal lobe status epilepticus.
Microinjection of kainic acid into the CA3 subfield of hippocampus in anesthetized rats elicited seizure-like hippocampal EEG activity that persisted for more than 180 minutes. There was a concomitant rise in plasma prolactin level that peaked at 15 to 20 minutes but endured less than 60 minutes. We conclude that plasma prolactin exhibited only transient elevations during experimental temporal lobe status epilepticus in rats.
Lin
Y Y
YY
Department of Neurology, Neurological Institute, Veterans General Hospital-Taipei, Taiwan, Republic of China.
Yen
S H
SH
Pan
J T
JT
Su
M S
MS
Wu
Z A
ZA
Chan
S H
SH
D000818:Animals; D004569:Electroencephalography; D006624:Hippocampus / Q000187:drug effects; D007608:Kainic Acid / Q000494:pharmacology; D008297:Male; D011388:Prolactin / Q000097:blood*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013226:Status Epilepticus / Q000097:blood* / Q000503:physiopathology; D013702:Temporal Lobe; D013997:Time Factors
D011388:Prolactin; D007608:Kainic Acid