[Actinoplanes brasiliensis INA 3802--a producer of peptide antibiotics].
In the screening programme for new antibiotics an actinomycete culture designated as 3802 was isolated from a soil sample. The culture produced a complex of peptide antibiotics belonging to the group of lantibiotics. The antibiotic complex included gardimycin (actagardin) and new antibiotics of the same group. By the taxonomic properties strain 3802 was classified as Actinoplanes brasiliensis not previously known to produce gardimycin. Conditions of the antibiotic complex biosynthesis by strain 3802, the isolation methods and biological properties were studied.
Terekhova
L P
LP
Institute of New Antibiotics, Russian Academy of Medical Sciences, Moscow, M.V. Lomonosov Moscow State University.
Galatenko
O A
OA
Laĭko
A V
AV
Sumarukova
I G
IG
Golova
T P
TP
Tolstykh
I V
IV
Kozlova
Iu I
IuI
D000192:Actinomycetales / Q000145:classification / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D001412:Bacillus subtilis / Q000187:drug effects; D003470:Culture Media; D010455:Peptides
D000900:Anti-Bacterial Agents; D003470:Culture Media; D010455:Peptides