[The inhibition of medullary reticulospinal neurons during the excitation of the dorsolateral portions of the pons blocking movement and muscle tonus in rats].
Hypothalamic stimulation increasing the muscle tone in hindlimbs, and excitation of the pontine dorsolateral areas inhibiting movements and the muscle tone in rats, were studied. Hypothalamic stimulation made 36.7% of the reticulospinal neurones to discharge in the form of short-latency spikes and to increase the muscle tone. The reticulospinal cells were completely inhibited by electrical stimulation of the pontine dorsolateral areas. 23.4% of the neurones only responded to the stimulation of the pontine dorsolateral areas. 35.9% of the cells did not respond to the stimulations at all. Excitation of the pontine inhibitory areas seems to prevent the descending activating effects from the brain rostral structures to spinal motor centres.
Mileĭkovskiĭ
B Iu
BIu
I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Acad. Sci., St. Petersburg, Russia.
Kiiashchenko
L I
LI
Titkov
E S
ES
D000818:Animals; D004558:Electric Stimulation / Q000379:methods; D018690:Excitatory Amino Acid Agonists / Q000494:pharmacology; D006614:Hindlimb; D007031:Hypothalamus / Q000502:physiology; D007608:Kainic Acid / Q000494:pharmacology; D008297:Male; D008526:Medulla Oblongata / Q000187:drug effects / Q000502:physiology*; D008845:Microinjections; D009046:Motor Neurons / Q000187:drug effects / Q000502:physiology*; D009068:Movement / Q000187:drug effects / Q000502:physiology*; D009129:Muscle Tonus / Q000187:drug effects / Q000502:physiology*; D009433:Neural Inhibition / Q000187:drug effects / Q000502:physiology*; D011149:Pons / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D013268:Stimulation, Chemical
D018690:Excitatory Amino Acid Agonists; D007608:Kainic Acid