title: [Biological properties of primary HIV-1 isolates with varying serotype].
abstract: Russian HIV variants with common (rapid/high SI and slow/low NSI) and rare (slow/low SI and rapid/high NSI) phenotypes are described. SI variants demonstrate a higher p24 concentration level than serotype-independent NSI. The majority of SI variants belonging to A, B, and C serotypes were isolated from patients with mainly stage B3. At stages B2 and C2, when the majority of viruses are characterized by NSI phenotype, serotype D isolates are characterized only by SI phenotype. The spectrum of cell tropism was wide for all rapid/high strains and narrow for all slow/low ones.
authors.forename: T A
authors.initials: TA
authors.lastname: Pashkova
authors.forename: N G
authors.initials: NG
authors.lastname: Iaroslavtseva
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Shchelkanov
authors.forename: M N
authors.initials: MN
authors.lastname: Papuashvili
authors.forename: I B
authors.initials: IB
authors.lastname: Sakhuriia
authors.forename: G V
authors.initials: GV
authors.lastname: Kornilaeva
authors.forename: E V
authors.initials: EV
authors.lastname: Karamov
mesh_terms: D000595:Amino Acid Sequence; D002460:Cell Line; D015699:HIV Envelope Protein gp120 / Q000737:chemistry; D015658:HIV Infections / Q000473:pathology / Q000821:virology*; D015497:HIV-1 / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D006801:Humans; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry; D010641:Phenotype; D017386:Sequence Homology, Amino Acid
chemical_list: D015699:HIV Envelope Protein gp120; C059762:HIV envelope protein gp120 (305-321); D010446:Peptide Fragments