title: An overview of contemporary approaches to antiarrhythmic therapy.
abstract: This review discusses the evolution in the approach to the therapy of cardiac arrhythmias that has occurred during the past 2 decades. The major changes have been driven by advances in understanding arrhythmia mechanisms, in bioengineering, and in clinical trials. It seems likely that progress in understanding the cellular and molecular basis of arrhythmias and their response to drug therapy may allow further identification of patient subsets in which specific therapies are indicated or contraindicated.
authors.affiliation: Department of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6602, USA. dan.roden@mcmail.vanderbilt.edu
authors.forename: D M
authors.initials: DM
authors.lastname: Roden
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000628:therapy*; D001698:Biomedical Engineering; D017115:Catheter Ablation; D006801:Humans
chemical_list: D000889:Anti-Arrhythmia Agents