Pulmonary arteriovenous fistula: presentation, diagnosis, and treatment.
Pulmonary arteriovenous fistulas (PAVFs) are rare vascular malformations of the lung. There is a strong association with Rendu-Osler-Weber disease. Although most patients are asymptomatic, PAVFs can cause dyspnea from a right-to-left shunt. They can also bleed and result in hemoptysis and hemothorax. Because of paradoxical emboli, various central nervous system complications have been described including stroke, and brain abscess. Currently, spiral computed tomography offers the most practical method for establishing the presence of PAVFs. Most patients should be treated. Therapeutic options include angiographic embolization with metal coils or balloon occlusion and surgical excision. Angiographic treatment has become the mainstay of therapy for most patients during the last decade. It is less invasive and can be repeated easily. Surgery, which usually consists of a conservative lung resection, is associated with low morbidity and a low recurrence rate. Both therapeutic approaches are discussed. The Mayo Clinic surgical experience of the last 20 years for PAVFs is presented.
Pick
A
A
Department of Surgery, Division of General Thoracic Surgery, Mayo Clinic and Mayo Foundation, 200 First Street, SW, Rochester, Minnesota 55905, USA.
Deschamps
C
C
Stanson
A W
AW
D000293:Adolescent; D000328:Adult; D000368:Aged; D000792:Angiography; D001164:Arteriovenous Fistula / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D001922:Brain Abscess / Q000209:etiology; D004417:Dyspnea / Q000209:etiology; D019320:Embolism, Paradoxical / Q000209:etiology; D004621:Embolization, Therapeutic; D005260:Female; D006469:Hemoptysis / Q000209:etiology; D006491:Hemothorax / Q000209:etiology; D006801:Humans; D008168:Lung / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D011655:Pulmonary Embolism / Q000209:etiology; D012008:Recurrence; D020521:Stroke / Q000209:etiology; D015996:Survival Rate; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications; D014057:Tomography, X-Ray Computed