title: A case of diabetes mellitus in Japanese Black cattle.
abstract: A 3 year-old female Japanese Black cattle was diagnosed as diabetes mellitus (DM). Hyperglycemia (295 mg/dl), increase of serum fructosamine (487 micromol/l), elevated glycosylated hemoglobin A1 (GHbA1; 10.9%), low concentration of serum insulin (< 1.0 microU/ ml), increased serum glucagon (399 pg/ml), and glucose intolerance (glucose disappearance rate; k=0.53) were noted. On the histopathologic findings in pancreas, insulitis with infiltration of mononuclear cells was found. This case suggests that serum fructosamine and GHbA1 are available parameters for understanding of pathophysiological conditions of bovine DM.
authors.affiliation: Veterinary Medical Science, Faculty of Agriculture, Miyazaki University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hasegawa
authors.forename: K
authors.initials: K
authors.lastname: Uchida
authors.forename: J
authors.initials: J
authors.lastname: Yanase
authors.forename: K
authors.initials: K
authors.lastname: Kitazaki
authors.forename: Y
authors.initials: Y
authors.lastname: Uchino
authors.forename: S
authors.initials: S
authors.lastname: Nakamura
authors.forename: H
authors.initials: H
authors.lastname: Sakimoto
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D003920:Diabetes Mellitus / Q000473:pathology / Q000662:veterinary*; D017809:Fatal Outcome; D005260:Female; D010179:Pancreas / Q000473:pathology