title: Successful dissolution of occlusive coronary thrombus with local administration of abciximab during PTCA.
abstract: Treatment of intracoronary thrombus poses difficult problems and may result in severe complications. We used a local delivery catheter (InfusaSleeve, LocalMed, Palo Alto, CA) to treat an occlusive coronary thrombus that was refractory to systemic thrombolysis and conventional angioplasty. After local administration of 10 mg of abciximab with this catheter there was successful resolution of coronary thrombus and vessel recanalization. Cathet. Cardiovasc. Intervent. 48:211-213, 1999.
authors.affiliation: Institute of Cardiology, the University of Milan, Fondazione "Monzino" IRCCS, Milan, Italy.
authors.forename: A L
authors.initials: AL
authors.lastname: Bartorelli
authors.forename: D
authors.initials: D
authors.lastname: Trabattoni
authors.forename: S
authors.initials: S
authors.lastname: Galli
authors.forename: L
authors.initials: L
authors.lastname: Grancini
authors.forename: S
authors.initials: S
authors.lastname: Cozzi
authors.forename: P
authors.initials: P
authors.lastname: Ravagnani
mesh_terms: D000077284:Abciximab; D000287:Administration, Topical; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation*; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D000925:Anticoagulants / Q000008:administration & dosage*; D006328:Cardiac Catheterization / Q000295:instrumentation*; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000008:administration & dosage*; D015912:Thrombolytic Therapy / Q000295:instrumentation*; D016896:Treatment Outcome
chemical_list: D000911:Antibodies, Monoclonal; D000925:Anticoagulants; D007140:Immunoglobulin Fab Fragments; D000077284:Abciximab