title: Swiss Caucasian population data for 13 STR loci using AmpFISTR profiler plus and cofiler PCR amplification kits.
abstract: Allele and genotype frequencies for the 13 core STR loci (D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, THO1, TPOX, CSF1PO, and D16S539) were determined in a Swiss Caucasian population sample (n = 206) using two commercially available multiplex PCR kits (AmpFISTR Profiler Plus and AmpFISTR Cofiler) and subsequent electrophoresis on an ABI PRISM CE 310 Genetic Analyzer instrument. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the 13 loci. The allelic frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a multiple STR locus DNA profile in the Swiss population.
authors.affiliation: Department of Forensic Medicine, Universität Bern, Switzerland. christian.gehrig@irm.unibe.ch
authors.forename: C
authors.initials: C
authors.lastname: Gehrig
authors.forename: M
authors.initials: M
authors.lastname: Hochmeister
authors.forename: U V
authors.initials: UV
authors.lastname: Borer
authors.forename: R
authors.initials: R
authors.lastname: Dirnhofer
authors.forename: B
authors.initials: B
authors.lastname: Budowle
mesh_terms: D000483:Alleles; D004247:DNA / Q000032:analysis; D016172:DNA Fingerprinting / Q000379:methods; D005787:Gene Frequency; D006801:Humans; D008297:Male; D018598:Minisatellite Repeats; D016133:Polymerase Chain Reaction / Q000379:methods; D011110:Polymorphism, Genetic; D011336:Probability; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D013557:Switzerland; D044465:White People / Q000235:genetics*
chemical_list: D011933:Reagent Kits, Diagnostic; D004247:DNA