Methods for X-ray diffraction analysis of macromolecular structures.
A modern approach to protein crystallography relies as much on molecular biology as on the 'core' crystallographic disciplines. Some recent, biologically significant structure determinations have demonstrated this and show the importance of new third generation synchrotron sources. Novel uses of well known phasing techniques have also been valuable in these structure determinations. For the majority of structures, advances in phasing techniques, data collection and processing and the associated computer programs have led to more effective structure determinations.
Beauchamp
J C
JC
Department of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK.
Isaacs
N W
NW
D000818:Animals; D018360:Crystallography, X-Ray / Q000379:methods*; D006801:Humans; D046911:Macromolecular Substances; D008565:Membrane Proteins / Q000648:ultrastructure
D046911:Macromolecular Substances; D008565:Membrane Proteins