title: Discovery of a new focus of human onchocerciasis in central Brazil.
abstract: An autochthonous case of human onchocerciasis was reported 13 years ago in the town of Minaçu, northern Goiás (Brazil), but a subsequent survey of the population using the traditional technique of examining skin biopsies with the light microscope failed to detect other cases. Recent surveys using more sensitive diagnostic techniques (serodiagnosis, DNA probes, Mazzotti test) that are detailed in this paper revealed the presence of other cases of the disease in Minaçu, the nearby town of Formoso and at the Buracão gold mine near Paranã. The data show that transmission of the disease has occurred to local people living in town and on farms and that gold miners (garimpeiros) are a likely source of infection.
authors.affiliation: Departamento de Entomologia, Instituto Oswaldo Cruz, Rio de Janeiro, Brazil. mherzog@gene.dbbm.fiocruz.br
authors.forename: M
authors.initials: M
authors.lastname: Maia-Herzog
authors.forename: A J
authors.initials: AJ
authors.lastname: Shelley
authors.forename: J E
authors.initials: JE
authors.lastname: Bradley
authors.forename: A P
authors.initials: AP
authors.lastname: Luna Dias
authors.forename: R H
authors.initials: RH
authors.lastname: Calvão
authors.forename: C
authors.initials: C
authors.lastname: Lowry
authors.forename: M
authors.initials: M
authors.lastname: Camargo
authors.forename: J M
authors.initials: JM
authors.lastname: Rubio
authors.forename: R J
authors.initials: RJ
authors.lastname: Post
authors.forename: G E
authors.initials: GE
authors.lastname: Coelho
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001938:Brazil / Q000453:epidemiology; D015342:DNA Probes; D005260:Female; D006801:Humans; D008297:Male; D008842:Microfilariae / Q000302:isolation & purification; D008875:Middle Aged; D017181:Onchocerca volvulus; D009855:Onchocerciasis / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D012698:Serologic Tests; D012867:Skin / Q000469:parasitology; D019371:Topography, Medical
chemical_list: D015342:DNA Probes