title: Aggressive form of pleural epithelioid haemangioendothelioma: complete response after chemotherapy.
abstract: Epithelioid haemangioendotheliomas are rare tumours of endothelial origin. They can develop in any tissue but occur principally in the lung and liver. Their usual course is a slow progression, so that they can be treated by surgery. In aggressive forms, no treatment has proved efficient to date. This study, describes a case of bilateral pleural epithelioid haemangioendothelioma that extended to the peritoneum. The histological diagnosis was confirmed by both conventional examination and immunohistochemistry. After six courses of carboplatine plus etoposide, a complete response was obtained. The complete remission is still lasting at 18 months after the diagnosis and the patient is healthy.
authors.affiliation: UPRES 2050, Dept of Chest Disease, Sainte-Marguerite Hospital, Marseilles, France.
authors.forename: C
authors.initials: C
authors.lastname: Pinet
authors.forename: A
authors.initials: A
authors.lastname: Magnan
authors.forename: L
authors.initials: L
authors.lastname: Garbe
authors.forename: M J
authors.initials: MJ
authors.lastname: Payan
authors.forename: D
authors.initials: D
authors.lastname: Vervloet
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001706:Biopsy; D016190:Carboplatin / Q000627:therapeutic use*; D005047:Etoposide / Q000627:therapeutic use*; D005260:Female; D018323:Hemangioendothelioma, Epithelioid / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000188:drug therapy*; D012074:Remission Induction; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed
chemical_list: D005047:Etoposide; D016190:Carboplatin