title: Eccrine porocarcinoma, tricholemmal carcinoma and multiple squamous cell carcinomas in a single patient.
abstract: A 75-year old woman without remarkable medical history presented with a large eccrine porocarcinoma of the trabelucar type located on her leg. This tumor was associated with two invasive squamous cell carcinomas of the legs, two Bowen's diseases of her thigh and arm and multiple actinic keratoses of the face. Despite major surgery, local recurrence of the porocarcinoma was observed 6 months later. During the 3-year follow-up after a second surgical intervention, this lesion did not reccur, but the patient developed a rapidly enlarging ulcerated tumor of the forehead which proved to be tricholemmal carcinoma. Although no carcinogenetic factor or familial history of multiple neoplasms could be evidenced, the occurrence of multiple tumors of various histogenesis over a 1 year period of time is unlikely to be fortuitous. Such an association of rare adnexal neoplasms has not yet been described.
authors.affiliation: Clinique dermatologique, Hôpitaux universitaires, 1, place de l'Hôpital, 67091 Strasbourg Cedex, France.
authors.forename: B
authors.initials: B
authors.lastname: Cribier
authors.forename: D
authors.initials: D
authors.lastname: Lipsker
authors.forename: E
authors.initials: E
authors.lastname: Grosshans
mesh_terms: D018250:Acrospiroma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D018295:Neoplasms, Basal Cell / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy