[The beneficial cytotoxicity of antiseptics. The controversial paradox of cutaneous ulcer treatment].
The pathogeny of cutaneous ulcers is complex. The role of a critical bacterial contamination is controversial. The use of topical antibiotics is unwise, and that of antiseptics is still a matter of debate. Some authors contend that antiseptics mitigate wound healing through a toxic effect upon keratinocytes and fibroblasts. Other researchers bring forward sound arguments to support the concept of beneficial cytotoxicity of antiseptics in the treatment of chronic cutaneous ulcers.
Hermanns
J F
JF
Service de Dermatopathologie, Université de Liège.
Paquet
P
P
Arrese
J E
JE
Piérard-Franchimont
C
C
Piérard
G E
GE
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000517:prevention & control; D002908:Chronic Disease; D006801:Humans; D012883:Skin Ulcer / Q000188:drug therapy* / Q000473:pathology
D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local