European paediatric hepatitis C virus network. Antenatal hepatitis C virus screening and management of infected women and their children: policies in Europe.
A postal survey of 31 European centres was conducted to document current practices regarding screening and management of hepatitis C virus (HCV)-infected pregnant women and their children. Antenatal HCV prevalence was low. Universal antenatal screening programmes were in place in ten centres, selective screening occurred in ten other centres, two did not specify the type of policy, and there was no screening programme in nine centres. Numbers of HCV-infected children were low. Breastfeeding was recommended for infants of infected mothers in ten centres, discouraged in ten centres, in three centres women were merely informed of the risks, and there were no guidelines in eight centres. Polymerase chain reaction was available in all centres. In 17 centres children born to HCV-infected women were seen every 3 months for at least the 1st year.


CONCLUSIONS
The optimum antenatal hepatitis C virus screening approach and the appropriateness of breastfeeding recommendations are unclear and this survey highlights the lack of uniformity in current practice.
Pembrey
L
L
University of Turin, Department of Pediatrics, Division of Immunology and Infectious Diseases, Regina Margherita Children's Hospital, Piazza Polonia 94, I-10126 Turin, Italy.
Newell
M L
ML
Tovo
P A
PA
D000046:Academic Medical Centers; D002648:Child; D003362:Cost-Benefit Analysis; D003625:Data Collection; D005060:Europe; D005260:Female; D017408:Guidelines as Topic; D016174:Hepacivirus / Q000302:isolation & purification; D006526:Hepatitis C / Q000175:diagnosis* / Q000635:transmission / Q000821:virology; D006761:Hospitals; D006801:Humans; D008403:Mass Screening / Q000191:economics; D016134:Organizational Policy; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011295:Prenatal Care / Q000592:standards