An overlapping subzone technique for MR-based elastic property reconstruction.
A finite element-based nonlinear inversion scheme for magnetic resonance (MR) elastography is detailed. The algorithm operates on small overlapping subzones of the total region of interest, processed in a hierarchical order as determined by progressive error minimization. This zoned approach allows for a high degree of spatial discretization, taking advantage of the data-rich environment afforded by the MR. The inversion technique is tested in simulation under high-noise conditions (15% random noise applied to the displacement data) with both complicated user-defined stiffness distributions and realistic tissue geometries obtained by thresholding MR image slices. In both cases the process has proved successful and has been capable of discerning small inclusions near 4 mm in diameter. Magn Reson Med 42:779-786, 1999.
Van Houten
E E
EE
Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA. elijah.van.houten@dartmouth.edu
Paulsen
K D
KD
Miga
M I
MI
Kennedy
F E
FE
Weaver
J B
JB
D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology; D001940:Breast / Q000033:anatomy & histology; D004548:Elasticity; D005260:Female; D020342:Finite Element Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male