How do the results of the diabetes control and complications trial relate to the practice of pediatrics: who should have intensive management?
The DCCT showed that any improvement in glycemic control decreases the risk of long-term complications. Although expensive, time consuming, and associated with increased risks of hypoglycemia and obesity, improved glycemic control is of benefit as long as hypoglycemia is avoided. Specific HbA1c target levels must be individualized and age appropriate.
Fenton
C L
CL
Department of Pediatrics, Walter Reed Army Medical Center, Washington, DC, USA.
Clemons
P M
PM
Francis
G L
GL
D000293:Adolescent; D002648:Child; D003422:Critical Care; D003920:Diabetes Mellitus / Q000517:prevention & control; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000628:therapy*; D006801:Humans; D006943:Hyperglycemia / Q000517:prevention & control / Q000628:therapy*; D007003:Hypoglycemia / Q000517:prevention & control; D009765:Obesity