[A comparison of the convulsive readiness of the brain, of long-term memory and of learning capacity and their structural equivalents in the postresuscitation period].
Clinical death of asphyxia was modelled in white rat experiments. After resuscitation passive avoidance tests were made to assess audiogenic convulsive readiness of the brain, the ability to learn and long-term memory. The experiments were made for 66 days. Light and electron microscopy studied cyto- and synaptoarchitectonics of the cerebrum sensomotor cortex. Deterioration of learning ability, enhancement of convulsive readiness of the brain and long-term memory were found. Changes in the long-term memory and convulsive readiness of the brain correlate with an increase in the number of large synaptic contacts.
Stepanov
S S
SS
Ereniev
S I
SI
Semchenko
V V
VV
D000161:Acoustic Stimulation; D000818:Animals; D001237:Asphyxia / Q000473:pathology / Q000503:physiopathology; D001921:Brain / Q000503:physiopathology* / Q000648:ultrastructure; D003214:Conditioning, Classical / Q000502:physiology; D004195:Disease Models, Animal; D005260:Female; D007858:Learning / Q000502:physiology*; D008297:Male; D008568:Memory / Q000502:physiology*; D008854:Microscopy, Electron; D051381:Rats; D017208:Rats, Wistar; D012151:Resuscitation; D012640:Seizures / Q000473:pathology / Q000503:physiopathology*; D013997:Time Factors