title: Simultaneous indocyanine green and fluorescein angiography in retinal pigment epithelium tear using the confocal scanning laser ophthalmoscope.
abstract: OBJECTIVE
  To describe the indocyanine green angiographic pattern of retinal pigment epithelium tears in the setting of age-related macular degeneration compared with the fluorescein angiographic features.
  
  
  METHODS
  Twelve consecutive patients (12 eyes) with a retinal pigment epithelium tear underwent simultaneous indocyanine green angiography and fluorescein angiography with the confocal scanning laser ophthalmoscope. The findings for the two modes were compared.
  
  
  RESULTS
  Choroidal neovascular membrane was evident beneath the rolled retinal pigment epithelium on indocyanine green angiograms in 11(92%) of 12 eyes: a focal neovascular membrane was apparent in five (42%) of 12 eyes, whereas a plaque neovascular membrane was seen in six (50%) of 12 eyes. In comparison, fluorescein angiography demonstrated late leakage as a result of occult choroidal neovascular membrane in nine (82%) of 11 eyes but no well-defined choroidal neovascular membrane.
  
  
  CONCLUSIONS
  Indocyanine green angiography is superior to fluorescein angiography for imaging choroidal neovascularization in cases of retinal pigment epithelium tear and may serve as an important adjunct to indocyanine green-guided laser treatment in selected cases.
authors.affiliation: Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Axer-Siegel
authors.forename: H
authors.initials: H
authors.lastname: Lichter
authors.forename: I
authors.initials: I
authors.lastname: Rosenblatt
authors.forename: E
authors.initials: E
authors.lastname: Priel
authors.forename: Y
authors.initials: Y
authors.lastname: Yassur
authors.forename: D
authors.initials: D
authors.lastname: Weinberger
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002199:Capillary Permeability; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000209:etiology; D015331:Cohort Studies; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D007834:Lasers; D008268:Macular Degeneration / Q000150:complications; D008297:Male; D008875:Middle Aged; D019721:Ophthalmoscopes; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012167:Retinal Perforations / Q000175:diagnosis* / Q000209:etiology
chemical_list: D007208:Indocyanine Green