title: [Systemic paracoccidioidomycosis with central nervous system involvement].
abstract: A clinical case of a patient bearing systemic paracoccidioidomycosis with regional ganglionic and oral exposure and later pulmonary involvement is presented. The patient was treated with specific drugs (amphotericin B, itraconazole, sulfamethoxazole-trimethoprim) and followed throughout a 6-year period and eventually died showing an extensive involvement of the central nervous system.
authors.affiliation: Santa Casa de Misericórdia de Pelotas, RS.
authors.forename: A L
authors.initials: AL
authors.lastname: Duarte
authors.forename: G
authors.initials: G
authors.lastname: Baruffa
authors.forename: H B
authors.initials: HB
authors.lastname: Terra
authors.forename: D V
authors.initials: DV
authors.lastname: Renck
authors.forename: D
authors.initials: D
authors.lastname: de Moura
authors.forename: C
authors.initials: C
authors.lastname: Petrucci
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D004359:Drug Therapy, Combination; D017809:Fatal Outcome; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D010229:Paracoccidioidomycosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014295:Trimethoprim / Q000627:therapeutic use; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D000935:Antifungal Agents; D017964:Itraconazole; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim