title: Isolation and sequence analysis of new peptaibol, boletusin, from Boletus spp.
abstract: A new peptaibol, boletusin, was isolated from the methanol extract of the fruiting body of the mushroom, Boletus spp. Sequential determination by positive FAB MS/MS showed that boletusin is a peptide consisting of 19 amino acids, with one acetylated N-terminus residue, phenylalanine, and a C-terminal amino alcohol, tryptophanol. This peptide showed antimicrobial activity against several Gram-positive bacteria.
authors.affiliation: Korea Research Institute of Bioscience and Biotechnology, Taejon.
authors.forename: S J
authors.initials: SJ
authors.lastname: Lee
authors.forename: W H
authors.initials: WH
authors.lastname: Yeo
authors.forename: B S
authors.initials: BS
authors.lastname: Yun
authors.forename: I D
authors.initials: ID
authors.lastname: Yoo
mesh_terms: D000363:Agaricales / Q000737:chemistry*; D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D054848:Peptaibols; D010455:Peptides; D017386:Sequence Homology, Amino Acid; D016339:Spectrometry, Mass, Fast Atom Bombardment
chemical_list: D000900:Anti-Bacterial Agents; D054848:Peptaibols; D010455:Peptides; C400128:boletusin