[Lipid inhibitors of phospholipase A2].
Results of studies of lipid inhibitors of phospholipase A2 are reviewed with a special emphasis on substrate specificity, special features of interfacial catalysis, and methods for the determination of the enzyme activity. The biological function of intracellular phospholipases is considered, and the possible use of inhibitors of a lipid nature for the modulation of the enzyme activity in pathological states of the human organism is discussed.
Bragina
N A
NA
Lomonosov State Academy of Fine Chemical Technology, Moscow, Russia.
Chupin
V V
VV
Bulgakov
V G
VG
Shal'nev
A N
AN
D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D007700:Kinetics; D010741:Phospholipases A / Q000037:antagonists & inhibitors* / Q000378:metabolism; D054467:Phospholipases A2; D013379:Substrate Specificity
D004791:Enzyme Inhibitors; D010741:Phospholipases A; D054467:Phospholipases A2