title: Dynamics of transient pores in stretched vesicles.
abstract: We image macroscopic transient pores in mechanically stretched giant vesicles. Holes open above a critical radius r(c1), grow up to a radius r(c2), and close. We interpret the upper limit r(c2) by a relaxation of the membrane tension as the holes expand. The closing of the holes is caused by a further relaxation of the surface tension when the internal liquid leaks out. A dynamic model fits our data for the growth and closure of pores.
authors.affiliation: Laboratoire Physico-Chimie Curie-Unité Mixte de Recherche 168 Centre National de la Recherche Scientifique/Institut Curie, 11, rue Pierre et Marie Curie 75248 Paris CEDEX 05, France. Sandre@curie.fr
authors.forename: O
authors.initials: O
authors.lastname: Sandre
authors.forename: L
authors.initials: L
authors.lastname: Moreaux
authors.forename: F
authors.initials: F
authors.lastname: Brochard-Wyart
mesh_terms: D002463:Cell Membrane Permeability; D004594:Electrophysiology; D005990:Glycerol / Q000494:pharmacology; D008051:Lipid Bilayers / Q000737:chemistry; D008564:Membrane Potentials; D008567:Membranes, Artificial; D008954:Models, Biological; D008962:Models, Theoretical; D011107:Polylysine / Q000737:chemistry; D013499:Surface Properties; D013997:Time Factors
chemical_list: D008051:Lipid Bilayers; D008567:Membranes, Artificial; D011107:Polylysine; D005990:Glycerol