title: Effects of single and repeated stresses on the expression of mRNA for alpha1-adrenoceptors in the rat hypothalamus and midbrain.
abstract: We examined the effects of single or repeated stress on the expression of mRNA for alpha1-adrenoceptors in the rat hypothalamus and midbrain using the reverse transcriptase-polymerase chain reaction (RT-PCR). Single stress significantly increased the mRNA level for alpha1-adrenoceptors in the midbrain, but had no effect on mRNA levels in the hypothalamus. Repeated stress significantly decreased mRNA levels for alpha1-adrenoceptors in both regions.
authors.affiliation: Department of Psychiatry, Mie University School of Medicine, Tsu, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Miyahara
authors.forename: T
authors.initials: T
authors.lastname: Komori
authors.forename: R
authors.initials: R
authors.lastname: Fujiwara
authors.forename: K
authors.initials: K
authors.lastname: Shizuya
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
authors.forename: M
authors.initials: M
authors.lastname: Ohmori
authors.forename: Y
authors.initials: Y
authors.lastname: Okazaki
mesh_terms: D000818:Animals; D007031:Hypothalamus / Q000378:metabolism*; D008297:Male; D008636:Mesencephalon / Q000378:metabolism*; D012333:RNA, Messenger / Q000235:genetics*; D051381:Rats; D017208:Rats, Wistar; D018340:Receptors, Adrenergic, alpha-1 / Q000235:genetics*; D012149:Restraint, Physical / Q000009:adverse effects*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013314:Stress, Mechanical; D013997:Time Factors
chemical_list: D012333:RNA, Messenger; D018340:Receptors, Adrenergic, alpha-1