[A case report of pure micrographia progressing over 5 years--an early sign of "pure akinesia"?].
We report a 68-year-old man who have had only slowly progressive micrographia in both hands over the past 5 years without rigidity, tremor, bradykinesia, and festination or freezing in walking. The fine finger movements were normal. PET studies suggested the diagnosis of progressive supranuclear palsy or pure akinesia. Administration of L-DOPA and L-threo-DOPS did not improve his micrographia. Festination and freezing in writing may contribute to the genesis of micrographia in this case. We postulate that "pure micrographia" is an early atypical sign of pure akinesia.
Hoshino
M
M
Department of Neurology, Tokyo Metropolitan Geriatric Hospital.
Kita
Y
Y
Mitani
K
K
Bando
M
M
Yamanouchi
H
H
D000368:Aged; D006236:Handwriting; D006801:Humans; D008297:Male; D009069:Movement Disorders / Q000503:physiopathology*