title: Effect of oxygen on tachycardia and arterial oxygen saturation during colonoscopy.
abstract: OBJECTIVE
  To evaluate the effect of supplementary oxygen on heart rate and arterial oxygen saturation during colonoscopy.
  
  
  METHODS
  Controlled study.
  
  
  METHODS
  Two university hospitals, Denmark.
  
  
  METHODS
  40 patients having colonoscopy.
  
  
  METHODS
  20 patients were given supplementary oxygen through nasal prongs (2 L/min), and 20 patients breathed room air during colonoscopy. All patients were given conscious sedation and were monitored with a pulse oximeter during colonoscopy.
  
  
  METHODS
  Tachycardia (pulse rate>100 min(-1)) and arterial oxygen desaturation (SpO2<90%) during colonoscopy.
  
  
  RESULTS
  There were no differences in the incidence of tachycardia or mean heart rate during endoscopy between the two groups, and no patient developed symptomatic cardiac arrhythmias or hypotensive episodes. 10 patients in the room air compared with none in the oxygen treatment group (p = 0.0004) had one or more episodes during which arterial oxygen saturation fell below 90% during colonoscopy, and mean oxygen saturation was higher in the oxygen treatment group than in the room air group (p < 0.001). No clinical complications occurred in either group.
  
  
  CONCLUSIONS
  Hypoxaemia and tachycardia are common during routine colonoscopy. The use of supplemental oxygen prevented hypoxaemia, but had no significant effect on heart rate.
authors.affiliation: Department of Surgical Gastroenterology 235, Hvidovre University Hospital, Denmark.
authors.forename: C
authors.initials: C
authors.lastname: Holm
authors.forename: M
authors.initials: M
authors.lastname: Christensen
authors.forename: S
authors.initials: S
authors.lastname: Schulze
authors.forename: J
authors.initials: J
authors.lastname: Rosenberg
mesh_terms: D000328:Adult; D000368:Aged; D003113:Colonoscopy / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D000860:Hypoxia / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D015994:Incidence; D008875:Middle Aged; D010092:Oximetry; D010100:Oxygen / Q000097:blood*; D010102:Oxygen Inhalation Therapy / Q000706:statistics & numerical data; D010313:Partial Pressure; D018709:Statistics, Nonparametric; D013610:Tachycardia / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*
chemical_list: D010100:Oxygen