Association of familial deficiency of mannose-binding lectin and meningococcal disease.
We report the case of an 18-year-old man with meningococcal meningitis and low serum concentrations of mannose-binding lectin (MBL). His mother and grandfather, who had also had meningitis in early adulthood, also had low concentrations of MBL in their serum.
Bax
W A
WA
Cluysenaer
O J
OJ
Bartelink
A K
AK
Aerts
P C
PC
Ezekowitz
R A
RA
van Dijk
H
H
D000293:Adolescent; D002352:Carrier Proteins / Q000097:blood* / Q000235:genetics*; D037222:Collectins; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D037102:Lectins / Q000097:blood / Q000235:genetics; D008297:Male; D008358:Mannose / Q000097:blood / Q000235:genetics; D008585:Meningitis, Meningococcal / Q000097:blood / Q000235:genetics*; D009345:Neisseria meningitidis / Q000302:isolation & purification*; D010375:Pedigree
D002352:Carrier Proteins; D037222:Collectins; D037102:Lectins; D008358:Mannose