title: recD sbcB sbcD mutants are deficient in recombinational repair of UV lesions by RecBC.
abstract: In recD sbcB sbcD mutants, repair of UV-irradiated DNA is strongly RecF dependent, indicating that RecBC is inactive. This finding suggests that exonuclease V, exonuclease I (SbcB), and the SbcCD nuclease play a redundant role in vivo, which is essential for the recombination activity of the RecBC complex during UV repair.
authors.affiliation: Génétique Microbienne, Institut National de la Recherche Agronomique, 78352 Jouy en Josas Cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: Seigneur
authors.forename: S D
authors.initials: SD
authors.lastname: Ehrlich
authors.forename: B
authors.initials: B
authors.lastname: Michel
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D004260:DNA Repair; D004926:Escherichia coli / Q000235:genetics* / Q000528:radiation effects; D029968:Escherichia coli Proteins; D043211:Exodeoxyribonuclease V; D005090:Exodeoxyribonucleases / Q000378:metabolism*; D005092:Exonucleases / Q000235:genetics*; D009154:Mutation; D011995:Recombination, Genetic; D014466:Ultraviolet Rays
chemical_list: D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D005090:Exodeoxyribonucleases; D005092:Exonucleases; C081229:sbcD protein, E coli; D043211:Exodeoxyribonuclease V; C468322:exodeoxyribonuclease V, E coli