title: A Rational Approach to Selective Recognition of NH(4)(+) over K(+).
abstract: An ion-selective electrode (ISE) based on receptor 1 is highly selective for binding NH(4)(+) over K(+) (lg K(NH(4)(+)/K(+))=-2.6); the three imine nitrogen atoms in 1 are ideally positioned for hydrogen bonding with the tetrahedral NH(4)(+) ion. This selectivity is considerably greater than that found for commercial ISEs based on nonactin (lg K(NH(4)(+)/K(+))=-1.0).
authors.affiliation: Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, Quebec H3A 2K6 (Canada).
authors.initials: J
authors.lastname: Chin
authors.initials: C
authors.lastname: Walsdorff
authors.initials: B
authors.lastname: Stranix
authors.initials: J
authors.lastname: Oh
authors.initials: HJ
authors.lastname: Chung
authors.initials: SM
authors.lastname: Park
authors.initials: K
authors.lastname: Kim