title: Primary neoplasms of the carpal bones.
abstract: Primary neoplasms of the carpal bones are rare. We found 44 primary tumors of the carpal bones of 26,800 bone neoplasms (prevalence, 0.16%). Original histologic slides and original radiographs were reviewed in 36 and 29 cases, respectively. Thirty-eight tumors (86%) were benign; 6 (14%) were malignant. The average patient age was 35 years. Benign lesions were diagnosed at a younger age (32 years) than malignant lesions (58 years). Benign tumors occurred more frequently in males (23 of 38 patients); the 6 malignant lesions were equally distributed by gender (3 males and 3 females; 95% confidence interval, 11.8-88.2). The most common tumor was osteoid osteoma (11 cases); the most common malignant neoplasm was hemangioendothelial sarcoma (3). The most common locations were the scaphoid (13 cases) and capitate (10), which together accounted for 52% of all neoplasms. Tumors were identified in every carpal bone except the trapezium. The diagnosis of tumor in a carpal bone should be considered in the undiagnosed painful wrist, especially in younger patients without imaging abnormalities.
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905, USA.
authors.forename: P M
authors.initials: PM
authors.lastname: Murray
authors.forename: R A
authors.initials: RA
authors.lastname: Berger
authors.forename: C Y
authors.initials: CY
authors.lastname: Inwards
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000453:epidemiology / Q000473:pathology; D002348:Carpal Bones; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies