The shortage of O-18 water.
Schoeller
D
D
D004734:Energy Metabolism; D006801:Humans; D007202:Indicators and Reagents / Q000600:supply & distribution*; D009765:Obesity / Q000378:metabolism*; D010103:Oxygen Isotopes; D014867:Water
D007202:Indicators and Reagents; D010103:Oxygen Isotopes; D014867:Water