title: Brain tumor surgery in geriatric patients: a critical analysis in 44 patients over 80 years.
abstract: BACKGROUND
  The decision of whether to operate on brain tumors in elderly patients has not been made easier despite diagnostic and therapeutic advances facilitating their diagnosis. Little is known about the outcome of brain tumor surgery in patients 80 years or older probably because the number of these patients, although increasing, is still small.
  
  
  METHODS
  The results of brain tumor surgery in 44 patients aged 80-86 years (mean age 83 years) were analyzed to determine which factors are relevant in the evaluation of the operative risk. The following parameters were analyzed with regard to the outcome: tumor volume, location, histopathology, preoperative condition, and concomitant diseases.
  
  
  RESULTS
  At discharge 19 patients (43%) had improved while 14 (32%) remained unchanged. Nevertheless, the overall results were unsatisfactory in 10 patients (23%), of whom 5 died in hospital. Tumor location, volume, and histopathology did not correlate with the outcome. The preoperative cerebrovascular condition and the existence of multiple concomitant diseases were clearly the determining factors for the outcome.
  
  
  CONCLUSIONS
  These results indicate that patients with life-threatening tumors or those causing persistent and intolerable brain dysfunction suffering from symptomatic cerebrovascular atherosclerosis as well as from multiple treatment requiring concomitant diseases did definitely not benefit from surgery.
authors.affiliation: Department of Neurosurgery, Benjamin Franklin Medical Center, Free University of Berlin, Germany.
authors.forename: T A
authors.initials: TA
authors.lastname: Pietilä
authors.forename: R
authors.initials: R
authors.lastname: Stendel
authors.forename: W E
authors.initials: WE
authors.lastname: Hassler
authors.forename: C
authors.initials: C
authors.lastname: Heimberger
authors.forename: J
authors.initials: J
authors.lastname: Ramsbacher
authors.forename: M
authors.initials: M
authors.lastname: Brock
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D002423:Cause of Death; D005260:Female; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000209:etiology; D011597:Psychomotor Performance; D012306:Risk; D012307:Risk Factors; D016896:Treatment Outcome