title: Vascular access system for continuous arterial infusion of a protease inhibitor in acute necrotizing pancreatitis.
abstract: We used a vascular access system (VAS) for continuous arterial infusion (CAI) of a protease inhibitor in two patients with acute necrotizing pancreatitis. The infusion catheter was placed into the dorsal pancreatic artery in the first patient and into the gastroduodenal artery in the second, via a femoral artery approach. An implantable port was then connected to the catheter and was secured in a subcutaneous pocket prepared in the right lower abdomen. No complications related to the VAS were encountered. This system provided safe and uncontaminated vascular access for successful CAI for acute pancreatitis.
authors.affiliation: Department of Radiology, Jikei University School of Medicine, Aoto Hospital, 6-41-2 Aoto, Katsushika-ku, Tokyo 125-8506, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Ganaha
authors.forename: T
authors.initials: T
authors.lastname: Yamada
authors.forename: N
authors.initials: N
authors.lastname: Yorozu
authors.forename: M
authors.initials: M
authors.lastname: Ujita
authors.forename: T
authors.initials: T
authors.lastname: Irie
authors.forename: Y
authors.initials: Y
authors.lastname: Fukuda
authors.forename: K
authors.initials: K
authors.lastname: Fukuda
authors.forename: S
authors.initials: S
authors.lastname: Tada
mesh_terms: D000328:Adult; D000368:Aged; D001550:Benzamidines; D005260:Female; D006146:Guanidines / Q000008:administration & dosage*; D006801:Humans; D015378:Imipenem / Q000008:administration & dosage; D007261:Infusions, Intra-Arterial / Q000295:instrumentation / Q000379:methods*; D008297:Male; D019283:Pancreatitis, Acute Necrotizing / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011480:Protease Inhibitors / Q000008:administration & dosage*; D011859:Radiography; D013845:Thienamycins / Q000008:administration & dosage
chemical_list: D001550:Benzamidines; D006146:Guanidines; D011480:Protease Inhibitors; D013845:Thienamycins; D015378:Imipenem; C032855:nafamostat