c-Irx2 expression reveals an early subdivision of the neural plate in the chick embryo.
We have cloned c-Irx2, a chick homologue of the Xiro2 and mIrx2 genes and a new member of the Iroquois family of homeodomain-containing transcription factors. Strikingly, c-Irx2 expression reveals an early subdivision of the neural plate at late primitive streak stages which later transiently resolves to a single stripe within the developing hindbrain corresponding to rhombomere 1.
Goriely
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A
Department of Human Anatomy and Genetics, University of Oxford, South Parks Rd., Oxford, UK.
Diez del Corral
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R
Storey
K G
KG
D000595:Amino Acid Sequence; D000818:Animals; D002531:Cerebellum / Q000196:embryology / Q000378:metabolism; D002642:Chick Embryo; D018076:DNA, Complementary / Q000378:metabolism; D015870:Gene Expression; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism*; D008636:Mesencephalon / Q000196:embryology / Q000378:metabolism*; D008969:Molecular Sequence Data; D012249:Rhombencephalon / Q000196:embryology / Q000378:metabolism*; D017386:Sequence Homology, Amino Acid; D013997:Time Factors; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
D018076:DNA, Complementary; D018398:Homeodomain Proteins; D014157:Transcription Factors