[Hodgkin's disease--diagnostic basis and therapy in light of randomized clinical trials].
Hodgkin Disease has a relatively good prognosis and high curability due to the effectiveness of risk adapted treatment. Protocol currently used at the Department of Haematology in Cracow is based on randomised multicentre clinical trials, summarised in this paper. Proper choice of the first line treatment is most important for overall survival--no salvage therapy for resistant or recurrent disease is equally effective. High dose chemotherapy with autologous stem cell support should be considered in certain clinical situations, as partial response or relapse after conventional treatment.
Jurczak
W
W
Kliniki Hematologii Collegium Medicum, Uniwersytetu Jagiellońksiego w Krakowie.
Nowak
W S
WS
Mensah
P
P
Skotnicki
A B
AB
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018380:Hematopoietic Stem Cell Transplantation; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D012008:Recurrence; D012307:Risk Factors; D015996:Survival Rate