title: Facile synthesis of N-protected gamma and delta-amino-beta-keto-esters.
abstract: The C-acylation of Meldrum's acid by protected amino acids, using isopropenyl chloroformate (IPCF) as the condensing agent, is described. The process is used to synthesize gamma and delta-amino-beta-keto-esters.
authors.affiliation: Department of Chemistry, Hunter College / CUNY, New York City, NY 10021, USA.
authors.forename: B
authors.initials: B
authors.lastname: Li
authors.forename: R W
authors.initials: RW
authors.lastname: Franck
mesh_terms: D000215:Acylation; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D004952:Esters