title: Melanotic peritoneal sarcomatosis originating from clear cell sarcoma.
abstract: Peritoneal sarcomatosis was found in a 53-year-old male who had a history of resection of clear cell sarcoma (CCS) of the right wrist 7 years previously. Both the previous wrist tumor and the peritoneal disseminants consisted of small, spindle-shaped cells occasionally containing melanophages. Histologic features, histochemical demonstration of argentaffin granules, immunohistochemical reaction with HMB 45, and the demonstration of a chimeric transcript of EWS-ATF-1 established the diagnosis of CCS in the peritoneal tumors. As far as we are aware, this is the first case of a peritoneal sarcomatosis associated with CCS.
authors.affiliation: Laboratory of Molecular and Cellular Pathology, Hokkaido University School of Medicine, Sapporo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Ohba
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Hiraga
authors.forename: T
authors.initials: T
authors.lastname: Ito
authors.forename: H
authors.initials: H
authors.lastname: Sawa
authors.forename: M
authors.initials: M
authors.lastname: Nagai
authors.forename: S I
authors.initials: SI
authors.lastname: Satoh
authors.forename: H
authors.initials: H
authors.lastname: Iwaki
authors.forename: K
authors.initials: K
authors.lastname: Nagashima
mesh_terms: D000951:Antigens, Neoplasm / Q000032:analysis; D017931:DNA Primers / Q000737:chemistry; D004273:DNA, Neoplasm / Q000032:analysis; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000737:chemistry / Q000473:pathology*; D058950:Melanoma-Specific Antigens; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000032:analysis; D015514:Oncogene Proteins, Fusion / Q000032:analysis; D010534:Peritoneal Neoplasms / Q000737:chemistry / Q000556:secondary*; D010537:Peritoneum; D012326:RNA Splicing; D020133:Reverse Transcriptase Polymerase Chain Reaction; D018227:Sarcoma, Clear Cell / Q000737:chemistry / Q000556:secondary*; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000473:pathology*; D014157:Transcription Factors / Q000032:analysis; D014953:Wrist
chemical_list: D000951:Antigens, Neoplasm; D017931:DNA Primers; D004273:DNA, Neoplasm; C111598:EWS-ATF1 fusion protein, human; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins; D015514:Oncogene Proteins, Fusion; D014157:Transcription Factors