title: Newer portable glucose meters--analytical improvement compared with previous generation devices?
abstract: BACKGROUND
  Newer glucose meters are easier to use, but direct comparisons with older instruments are lacking. We wished to compare analytical performances of four new and four previous generation meters.
  
  
  METHODS
  On average, 248 glucose measurements were performed with two of each brand of meter on capillary blood samples from diabetic patients attending our outpatient clinic. Two to three different lots of strips were used. All measurements were performed by one experienced technician, using blood from the same sample for the meters and the comparison method (Beckman Analyzer 2). Results were evaluated by analysis of clinical relevance using the percentage of values within a maximum deviation of 5% from the reference value, by the method of residuals, by error grid analysis, and by the CVs for measurements in series.
  
  
  RESULTS
  Altogether, 1987 blood glucose values were obtained with meters compared with the reference values. By error grid analysis, the newer devices gave more accurate results without significant differences within the group (zone A, 98-98.5%). Except for the One Touch II (zone A, 98.5%), the other older devices were less exact (zone A, 87-92.5%), which was also true for all other evaluation procedures.
  
  
  CONCLUSIONS
  New generation blood glucose meters are not only smaller and more aesthetically appealing but are more accurate compared with previous generation devices except the One Touch II. The performance of the newer meters improved but did not meet the goals of the latest American Diabetes Association recommendations in the hands of an experienced operator.
authors.affiliation: 2nd Department of Medicine, St. Johanns Spital, Salzburg General Hospital, Muellner Hauptstrasse 48, A-5020 Salzburg, Austria. R.Weitgasser@lkasbg.gv.at
authors.forename: R
authors.initials: R
authors.lastname: Weitgasser
authors.forename: B
authors.initials: B
authors.lastname: Gappmayer
authors.forename: M
authors.initials: M
authors.lastname: Pichler
mesh_terms: D000553:Ambulatory Care; D001786:Blood Glucose / Q000032:analysis*; D019411:Clinical Laboratory Techniques / Q000295:instrumentation; D003920:Diabetes Mellitus / Q000097:blood; D006801:Humans; D012016:Reference Values
chemical_list: D001786:Blood Glucose