title: A new eyedrop dispensing bottle.
abstract: OBJECTIVE
  To report a new eyedrop dispensing container that allows administration of eyedrops while the head of the patient is in the usual upright position.
  
  
  METHODS
  An eyedrop dispensing container with a dip tube extending to the bottom, an automatic venting mechanism, and an angulated dispensing tube was developed.
  
  
  RESULTS
  The problem of unwanted efflux of fluid was solved by incorporating the automatic venting mechanism. The final design includes an adjustable, angulated dispensing tube and "single structure" construction incorporating the cap. A removable cheek rest is also provided. The design allows eyedrops to be instilled while the patient's head is in the upright position and even when spectacles are being worn. A prototype 15-ml bottle delivered an eyedrop volume of 19.7+/-1.2 microl (mean +/- SD) (n = 75).
  
  
  CONCLUSIONS
  This new eyedrop bottle should allow precise self-administration of eyedrops by a patient in front of a mirror, without a need to change head position.
authors.affiliation: Biophysics Laboratory, Department of Ophthalmology, Duke University Medical Center, Duke University Eye Center, Durham, North Carolina 27710, USA. overa004@mc.duke.edu
authors.forename: R F
authors.initials: RF
authors.lastname: Overaker
authors.forename: B C
authors.initials: BC
authors.lastname: Dodge
authors.forename: D L
authors.initials: DL
authors.lastname: Epstein
mesh_terms: D016503:Drug Delivery Systems; D004349:Drug Packaging; D004867:Equipment Design; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D011187:Posture
chemical_list: D009883:Ophthalmic Solutions