title: A population-based study of children with cerebral tuberculosis in New South Wales.
abstract: OBJECTIVE
  To determine the incidence of childhood cerebral tuberculosis (tuberculous meningitis [TBM] and tuberculoma) in a defined population.
  
  
  METHODS
  Retrospective, population-based study.
  
  
  METHODS
  All resident children aged up to 14 years in New South Wales diagnosed with cerebral tuberculosis, from 1982 to 1996.
  
  
  METHODS
  Population-based incidence of childhood TBM.
  
  
  RESULTS
  10 children with TBM and one with tuberculoma were identified in the 15 years. The incidence of TBM was 0.053 (95% CI, 0.025-0.097) per 100,000. Eight of the 10 TBM patients were born in Australia and five were of white European origin. Only one had been vaccinated with BCG vaccine. Three of the children died.
  
  
  CONCLUSIONS
  The incidence of childhood TBM in New South Wales is low, and comparable with that in other First World countries.
authors.affiliation: Royal Alexandra Hospital for Children, Sydney, NSW.
authors.forename: N
authors.initials: N
authors.lastname: Arestis
authors.forename: Y J
authors.initials: YJ
authors.lastname: Tham
authors.forename: P B
authors.initials: PB
authors.lastname: McIntyre
authors.forename: D
authors.initials: D
authors.lastname: Isaacs
authors.forename: P
authors.initials: P
authors.lastname: Palasanthiran
authors.forename: J K
authors.initials: JK
authors.lastname: Ferguson
authors.forename: I
authors.initials: I
authors.lastname: Wilkinson
authors.forename: D
authors.initials: D
authors.lastname: Dawson
authors.forename: A J
authors.initials: AJ
authors.lastname: Christensen
mesh_terms: D000293:Adolescent; D001927:Brain Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009517:New South Wales / Q000453:epidemiology; D012189:Retrospective Studies; D014375:Tuberculoma / Q000175:diagnosis / Q000453:epidemiology*; D014390:Tuberculosis, Meningeal / Q000175:diagnosis / Q000453:epidemiology*