[Genetic markers of hypertension].
Essential hypertension is a widespread multifactorial pathology which is probably controlled by numerous genes. Twenty to forty percent of hypertension may be genetically determined. In this review, polymorphism of three group of candidate genes is analyzed. Products of these genes are most likely involved in hypertension development. These are the genes controlling the renin-angiotensin system, ionic channels, and nitric oxide system and NO-synthase.
Chistiakov
D A
DA
State Research Institute of Genetics and Selection for Industrial Microorganisms, Moscow, Russia.
Turakulov
R I
RI
D005819:Genetic Markers; D006801:Humans; D006973:Hypertension / Q000235:genetics* / Q000503:physiopathology; D008903:Minerals / Q000378:metabolism; D009569:Nitric Oxide / Q000502:physiology; D019001:Nitric Oxide Synthase / Q000235:genetics; D011110:Polymorphism, Genetic; D012084:Renin-Angiotensin System / Q000235:genetics; D012307:Risk Factors
D005819:Genetic Markers; D008903:Minerals; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase