title: Use of prothrombin complex concentrates for prophylaxis and treatment of bleeding episodes in patients with hereditary deficiency of prothrombin, factor VII, factor X, protein C protein S, or protein Z.
authors.affiliation: Klinik I für Innere Medizin der Universität zu Köln, Germany. e.lechler@medizin.uni-Koeln.de
authors.forename: E
authors.initials: E
authors.lastname: Lechler
mesh_terms: D001779:Blood Coagulation Factors / Q000627:therapeutic use*; D001798:Blood Proteins / Q000172:deficiency; D020147:Coagulation Protein Disorders / Q000188:drug therapy* / Q000235:genetics; D005168:Factor VII Deficiency / Q000188:drug therapy; D005171:Factor X Deficiency / Q000188:drug therapy; D006470:Hemorrhage / Q000188:drug therapy* / Q000517:prevention & control*; D006801:Humans; D007020:Hypoprothrombinemias / Q000188:drug therapy; D020151:Protein C Deficiency / Q000188:drug therapy; D018455:Protein S Deficiency / Q000188:drug therapy; D011516:Prothrombin / Q000627:therapeutic use*
chemical_list: D001779:Blood Coagulation Factors; D001798:Blood Proteins; C026080:plasma protein Z; C025667:prothrombin complex concentrates; D011516:Prothrombin