title: Acoustic airway profiles in unilateral cleft palate patients.
abstract: OBJECTIVE
  This study investigates the nasal airway in unilateral cleft palate patients by means of a noninvasive, objective diagnostic method that provides topographic information about the airway profile.
  
  
  METHODS
  A consecutive sample of patients was measured.
  
  
  METHODS
  Cleft palate rehabilitation center of the University of Mainz, Germany.
  
  
  METHODS
  Forty-nine subjects were investigated: 34 full-grown patients with complete unilateral cleft lip and palate and 15 controls with subjective normal nasal patency.
  
  
  METHODS
  A transnasal series of three acoustic measurements of nasal volume was performed per nostril; measurements were taken both before and after decongestion with 0.3 mg xylometazoline per nostril. Minimum cross-sectional area, nasal volume, and decongestion capacity were calculated for both the cleft side and the contralateral side and for both nasal sides in controls.
  
  
  RESULTS
  Pathologic obstructions (<0.4 cm2) were detected on the cleft side in 75% of patients but were detected in only 15% of patients on the contralateral side (p < .001). The valve area of the cleft side (0.32 +/- 0.2 cm2) yielded significantly (p < .001) lower cross-sectional values compared with the contralateral side (0.56 +/- 0.1 cm2). Total nasal volume was determined to be 35% smaller on the cleft side (p < .001). Significantly higher decongestion capacity was verified on the cleft side, thus indicating mucosal hypertrophy.
  
  
  CONCLUSIONS
  Despite a wide range of interindividual variability, we recognized a characteristic "descending W"" airway pattern in cleft palate patients. Acoustic rhinometry seems to be a powerful tool for acquiring topographic information about the individual airway profile. It has proven helpful in visualizing the location and amount of pathologic obstructions, rendering it especially useful for preoperative investigation and quality control in corrective cleft nose surgery.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Mainz, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Kunkel
authors.forename: U
authors.initials: U
authors.lastname: Wahlmann
authors.forename: W
authors.initials: W
authors.lastname: Wagner
mesh_terms: D000162:Acoustics; D000293:Adolescent; D000328:Adult; D001703:Biophysics / Q000706:statistics & numerical data; D002972:Cleft Palate / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use; D009296:Nasal Cavity / Q000187:drug effects / Q000503:physiopathology*; D014663:Nasal Decongestants / Q000627:therapeutic use; D015508:Nasal Obstruction / Q000188:drug therapy / Q000503:physiopathology; D009666:Nose / Q000002:abnormalities; D018709:Statistics, Nonparametric
chemical_list: D007093:Imidazoles; D014663:Nasal Decongestants; C009695:xylometazoline