Isolation and sequence analysis of new peptaibol, boletusin, from Boletus spp.
A new peptaibol, boletusin, was isolated from the methanol extract of the fruiting body of the mushroom, Boletus spp. Sequential determination by positive FAB MS/MS showed that boletusin is a peptide consisting of 19 amino acids, with one acetylated N-terminus residue, phenylalanine, and a C-terminal amino alcohol, tryptophanol. This peptide showed antimicrobial activity against several Gram-positive bacteria.
Lee
S J
SJ
Korea Research Institute of Bioscience and Biotechnology, Taejon.
Yeo
W H
WH
Yun
B S
BS
Yoo
I D
ID
D000363:Agaricales / Q000737:chemistry*; D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D054848:Peptaibols; D010455:Peptides; D017386:Sequence Homology, Amino Acid; D016339:Spectrometry, Mass, Fast Atom Bombardment
D000900:Anti-Bacterial Agents; D054848:Peptaibols; D010455:Peptides; C400128:boletusin