[Analysis of the interaction of mutations at the Drosophila melanogaster Su(mg), mod(mdg4), and su(Hw) loci].
The mod(mdg4)1u1 mutation modifies the phenotypic expression of mutations induced by the MDG4 insertion. The Suppressor of modifier mdg4 (Su(mg)) gene family was described earlier. Most Su(mg) mutations completely suppressed the negative effect of the mod(mdg4)1u1 mutation on transcription of the yellow gene. However, only a few Su(mg) mutations suppressed the inhibiting effect of mod(mdg4)1u1 on transvection between the y59b/y2 alleles. The interaction of the mod(mdg4) and Su(mg) mutations with the su(Hw) mutation was studied. The phenotypic expression of the Su(mg) and mod(mdg4)1u1 mutations was shown to depend on the presence of the functional protein su(Hw).
Bezborodova
E A
EA
Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
Georgiev
P G
PG
D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D004251:DNA Transposable Elements; D004331:Drosophila melanogaster / Q000235:genetics*; D017344:Genes, Insect; D016153:Genes, Suppressor; D009154:Mutation; D010641:Phenotype; D014158:Transcription, Genetic
D004251:DNA Transposable Elements