title: Cutaneous sarcoidosis with cardiac involvement.
abstract: Despite the clinical importance of cardiac involvement in the prognosis of sarcoidosis, it is often overlooked because of the subclinical disease progression and difficulty in diagnosis. We report here five patients with cutaneous sarcoidosis lesions where cardiac involvement was detected with the appearance of mild cardiac symptoms on a careful examination of the heart after cutaneous sarcoidosis was diagnosed. In four of the five cases, the patients had annular lesions while the fifth case showed a nodular eruption on the face. Three of the five patients showed complete AV block while one showed complete right bundle block and left bundle anterior branch block. All four patients with conduction disturbances underwent a permanent pacemaker implantation with prednisolone tapering therapy. The remaining patient had congestive heart failure and was treated with prednisolone alone. The present findings support the belief that sarcoidosis patients with cutaneous lesions, especially facial annular lesions, should be carefully examined and monitored for cardiac involvement, even in cases without apparent cardiac symptoms.
authors.affiliation: Department of Dermatology, Faculty of Medicine, Kyoto University, Kyoto 606-0813, Japan. hokamoto@takii.kmu.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Okamoto
authors.forename: K
authors.initials: K
authors.lastname: Mizuno
authors.forename: E
authors.initials: E
authors.lastname: Ohtoshi
mesh_terms: D000368:Aged; D002037:Bundle-Branch Block / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006327:Heart Block / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D011239:Prednisolone / Q000008:administration & dosage; D011379:Prognosis; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D012871:Skin Diseases / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
chemical_list: D011239:Prednisolone