title: [Local dermonecrotic loxoscelism in children bitten by the spider Loxosceles reclusa (the "violin" spider)].
abstract: This is an observational retrospective study. Our goal is to describe the local dermonecrotic reaction occurring after a spider bite in eleven pediatric patients. In seven (63.7%), the spider was identified as Loxosceles reclusa, and in four, bites were presumptive. The main symptoms and signs were pain, erythema, swelling, blisters, and vasculitis in five patients. There was a significant relationship between the time of onset before the treatment and the severity of the lesions (63.4 hours in the severe cases vs 14.4 hours in the mild cases, p < 0.05), as well the time spent in the emergency room (50 hours vs 10 hours respectively, p < 0.05). Treatment with dapsone, 1 mg/kg/24 h, and/or paracetamol and dicloxacillin was successful; one case required surgical treatment. No systemic loxoscelism occurred in this patient.
authors.affiliation: Departamento de Admisión Continua y Toxicología, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, México, D.F.
authors.forename: P
authors.initials: P
authors.lastname: Escalante-Galindo
authors.forename: M A
authors.initials: MA
authors.lastname: Montoya-Cabrera
authors.forename: V M
authors.initials: VM
authors.lastname: Terroba-Larios
authors.forename: A R
authors.initials: AR
authors.lastname: Nava-Juárez
authors.forename: I
authors.initials: I
authors.lastname: Escalante-Flores
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D002648:Child; D003622:Dapsone / Q000008:administration & dosage; D004009:Dicloxacillin / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D006801:Humans; D009336:Necrosis; D010406:Penicillins / Q000008:administration & dosage; D012189:Retrospective Studies; D012867:Skin / Q000473:pathology*; D001098:Spider Bites / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
chemical_list: D018712:Analgesics, Non-Narcotic; D000894:Anti-Inflammatory Agents, Non-Steroidal; D010406:Penicillins; D000082:Acetaminophen; D003622:Dapsone; D004009:Dicloxacillin