title: Chromosome segregation and cell division defects in recBC sbcBC ruvC mutants of Escherichia coli.
abstract: The RuvC protein is important for DNA recombination and repair in Escherichia coli. The present work shows that a ruvC null mutation introduced into a recBC sbcBC background causes severe defects in chromosome segregation and cell division. Both defects were found to result from abortive recombination initiated by the RecA protein.
authors.affiliation: Department of Molecular Genetics, Ruer Boskovic Institute, 10001 Zagreb, Croatia. zahradka@rudjer.irb.hr
authors.forename: D
authors.initials: D
authors.lastname: Zahradka
authors.forename: K
authors.initials: K
authors.lastname: Vlahović
authors.forename: M
authors.initials: M
authors.lastname: Petranović
authors.forename: D
authors.initials: D
authors.lastname: Petranović
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D020090:Chromosome Segregation; D002876:Chromosomes, Bacterial / Q000648:ultrastructure*; D004261:DNA Replication / Q000235:genetics; D004269:DNA, Bacterial / Q000096:biosynthesis; D004706:Endodeoxyribonucleases / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics*; D029968:Escherichia coli Proteins; D043211:Exodeoxyribonuclease V; D005090:Exodeoxyribonucleases / Q000235:genetics*; D011995:Recombination, Genetic / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D029968:Escherichia coli Proteins; C069806:ruvC protein, E coli; D004706:Endodeoxyribonucleases; D005090:Exodeoxyribonucleases; C028450:exodeoxyribonuclease I; D043211:Exodeoxyribonuclease V; C468322:exodeoxyribonuclease V, E coli