title: Regional assessment of wall curvature and wall stress in left ventricle with magnetic resonance imaging.
abstract: Left ventricular functional abnormalities are associated with regional increases of wall stress and modifications of wall curvature. This study describes the integration of the short-axis and long-axis wall curvatures for determining peak systolic wall stress. Quantification was realized with cine magnetic resonance imaging (MRI) from the location of the endocardial and epicardial borders of the left ventricle on pairs of consecutive short-axis sections. Fifteen normal volunteers were subjected to cine MRI, and different methods of calculating peak systolic wall stress were compared. A short-axis analysis showed a 55 +/- 13% increase of the circumferential mean of the peak systolic wall stress between apical and basal sections. Regarding the curvature, no significant increase of wall stress was observed except on the septal wall (31 +/- 18%). Short-axis studies proved to be insufficient for determining the regional variations of left ventricular wall stress and for providing normal reference values for the location of abnormal regions in patients.
authors.affiliation: Department of Biophysics, University Hospital of Angers, 49033 Angers Cedex 01, France.
authors.forename: P
authors.initials: P
authors.lastname: Balzer
authors.forename: A
authors.initials: A
authors.lastname: Furber
authors.forename: S
authors.initials: S
authors.lastname: Delépine
authors.forename: F
authors.initials: F
authors.lastname: Rouleau
authors.forename: F
authors.initials: F
authors.lastname: Lethimonnier
authors.forename: O
authors.initials: O
authors.lastname: Morel
authors.forename: A
authors.initials: A
authors.lastname: Tadéi
authors.forename: P
authors.initials: P
authors.lastname: Jallet
authors.forename: P
authors.initials: P
authors.lastname: Geslin
authors.forename: J J
authors.initials: JJ
authors.lastname: le Jeune
mesh_terms: D000328:Adult; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009200:Myocardial Contraction; D011859:Radiography; D016276:Ventricular Function; D016277:Ventricular Function, Left / Q000502:physiology*