title: Fluid dynamic characterization of operating conditions for continuous flow blood pumps.
abstract: As continuous flow pumps become more prominent as long-term ventricular assist devices, the wide range of conditions under which they must be operated has become evident. Designed to operate at a single, best-efficiency, operating point, continuous flow pumps are required to perform at off-design conditions quite frequently. The present study investigated the internal fluid dynamics within two representative rotary fluid pumps to characterize the quality of the flow field over a full range of operating conditions. A Nimbus/UoP axial flow blood pump and a small centrifugal pump were used as the study models. Full field visualization of flow features in the two pumps was conducted using a laser based fluorescent particle imaging technique. Experiments were performed under steady flow conditions. Flow patterns at inlet and outlet sections were visualized over a series of operating points. Flow features specific to each pump design were observed to exist under all operating conditions. At off-design conditions, an annular region of reverse flow was commonly observed within the inlet of the axial pump, while a small annulus of backflow in the inlet duct and a strong disturbed flow at the outlet tongue were observed for the centrifugal pump. These observations were correlated to a critical nondimensional flow coefficient. The creation of a "map" of flow behavior provides an additional, important criterion for determining favorable operating speed for rotary blood pumps. Many unfavorable flow features may be avoided by maintaining the flow coefficient above a characteristic critical coefficient for a particular pump, whereas the intrinsic deleterious flow features can only be minimized by design improvement. Broadening the operating range by raising the band between the critical flow coefficient and the designed flow coefficient, is also a worthy goal for design improvement.
authors.affiliation: McGowan Center for Artificial Organ Development, University of Pittsburgh Medical Center, Pennsylvania 15219, USA.
authors.forename: Z J
authors.initials: ZJ
authors.lastname: Wu
authors.forename: J F
authors.initials: JF
authors.lastname: Antaki
authors.forename: G W
authors.initials: GW
authors.lastname: Burgreen
authors.forename: K C
authors.initials: KC
authors.lastname: Butler
authors.forename: D C
authors.initials: DC
authors.lastname: Thomas
authors.forename: B P
authors.initials: BP
authors.lastname: Griffith
mesh_terms: D002498:Centrifugation; D006353:Heart-Assist Devices; D006801:Humans