title: Cathepsin P, a novel protease in mouse placenta.
abstract: The complete cDNA nucleotide sequence of a novel cathepsin derived from mouse placenta, termed cathepsin P, was determined. mRNA for cathepsin P was expressed in placenta and at lower levels in visceral yolk sac, but could not be detected in a range of adult tissues. The expression pattern of this protease indicates that it probably plays an important role during implantation and fetal development.
authors.affiliation: Laboratory of Enzymology, Department of Research, Alfred I. duPont Hospital for Children, Wilmington, DE 19899, USA.
authors.forename: K
authors.initials: K
authors.lastname: Sol-Church
authors.forename: J
authors.initials: J
authors.lastname: Frenck
authors.forename: D
authors.initials: D
authors.lastname: Troeber
authors.forename: R W
authors.initials: RW
authors.lastname: Mason
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D056657:Cathepsin K; D056668:Cathepsin L; D002403:Cathepsins / Q000737:chemistry / Q000235:genetics*; D003001:Cloning, Molecular; D003546:Cysteine Endopeptidases; D005314:Embryonic and Fetal Development; D010450:Endopeptidases; D020224:Expressed Sequence Tags; D005260:Female; D051379:Mice; D008969:Molecular Sequence Data; D009928:Organ Specificity; D010920:Placenta / Q000201:enzymology*; D012333:RNA, Messenger / Q000032:analysis / Q000235:genetics; D051381:Rats; D016415:Sequence Alignment
chemical_list: D012333:RNA, Messenger; D002403:Cathepsins; D010450:Endopeptidases; D003546:Cysteine Endopeptidases; D056668:Cathepsin L; C534278:Ctsl protein, mouse; C534280:Ctsl protein, rat; D056657:Cathepsin K; C534132:Ctsk protein, mouse; C534133:Ctsk protein, rat