Pneumocystis carinii carriage in immunocompetent patients with primary pulmonary disorders as detected by single or nested PCR.
Ninety-five bronchoalveolar lavage specimens from 63 immunocompetent adult patients with primary pulmonary disease were analyzed for Pneumocystis carinii colonization by primary and nested PCR. Twelve of 63 patients (19%) were PCR positive. None of them developed P. carinii pneumonia. These results suggest that P. carinii carriage may exist in immunocompetent patients with underlying pulmonary disease.
Sing
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A
Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Munich, Germany. sing@m3401.mpk.med.uni-muenchen.de
Roggenkamp
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A
Autenrieth
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IB
Heesemann
J
J
D000328:Adult; D000368:Aged; D002353:Carrier State; D005260:Female; D006801:Humans; D007121:Immunocompetence; D008171:Lung Diseases / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D011010:Pneumocystis / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction