title: [Cerebral agyria-pachygyria in a child with Werdnig-Hoffmann disease].
abstract: Werdnig-Hoffmann disease refers to the severe infantile form of anterior horn cell degeneration. We report an association between Werdnig-Hoffmann disease and agyria-pachygyria. Examples of anterior horn cell disease with lesions in the central nervous system (notably thalamus and cerebellum) have been considered unusual "variants" of Werdnig-Hoffmann disease. This association between Werdnig-Hoffmann disease and agyria-pachygyria has, to our knowledge, never been described.
authors.affiliation: Service de Pédiatrie, Hôpital Saint-Antoine, Lille.
authors.forename: F
authors.initials: F
authors.lastname: Cneude
authors.forename: S
authors.initials: S
authors.lastname: Sukno
authors.forename: F
authors.initials: F
authors.lastname: Boidein
authors.forename: M B
authors.initials: MB
authors.lastname: Dehouck
authors.forename: A
authors.initials: A
authors.lastname: Bourlet
authors.forename: G
authors.initials: G
authors.lastname: Vittu
mesh_terms: D002540:Cerebral Cortex / Q000002:abnormalities* / Q000473:pathology*; D002648:Child; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014897:Spinal Muscular Atrophies of Childhood / Q000473:pathology*