title: Changing prescribing in the light of tolerability concerns: how is this best achieved?
abstract: Despite our knowledge regarding the efficacy, tolerability and optimal use of drugs, suboptimal prescribing still occurs. In view of all the factors that influence prescribing, this is not surprising. The focus of drug tolerability has changed from 'choosing the best alternative' when a drug is prescribed, to a balanced decision incorporating various different treatments from separate healthcare providers. This article reviews strategies that may influence prescribing behaviour and discusses practical considerations for achieving optimal prescribing in view of tolerability concerns. The patient has a major influence on prescribing and, with the current diversification of healthcare, the patient now controls prescribing behaviour more than ever before. Communication between healthcare providers consequently assumes a vital role. If messages are to be coherent and transferable, it is increasingly important that healthcare workers communicate effectively with one another regarding patients, prescribing patterns, and drug tolerability issues.
authors.affiliation: Department of Social Pharmacy and Pharmacoepidemiology, University Centre for Pharmacy, Groningen University Institute for Drug Exploration, The Netherlands.
authors.forename: C S
authors.initials: CS
authors.lastname: de Vries
authors.forename: C A
authors.initials: CA
authors.lastname: Duggan
authors.forename: T F
authors.initials: TF
authors.lastname: Tromp
authors.forename: L T
authors.initials: LT
authors.lastname: de Jong-van den Berg
mesh_terms: D011307:Drug Prescriptions; D004361:Drug Tolerance; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D004364:Pharmaceutical Preparations / Q000008:administration & dosage
chemical_list: D004364:Pharmaceutical Preparations