[Otolith-autonomic reactions in waking Macaca mulatta monkeys].
The aim was to determine a technique and parameters to test the otolith-autonomous reflex responses in conscious monkeys. The study involved 8 Macacas mulatta weighing 3 to 5 kg with subcutaneously pre-implanted electrodes to record ECG, rheopneumogram, and myoelectric activity of the stomach. The animals were seated in primate couches in which their bodies were softly restrained whereas their heads were restrained rigidly with plastic rings mounted on the cranium. Subsiding motion of a flat-parallel swing with the proper period of 3 s and starting amplitudes 20 cm (0.08 g) and 40 cm (0.16 g) exerted vestibular stimulation along the interaural axis. The monkeys responded to stimulation by altering the external breathing, myoelectric activity of the stomach, and cardiac rhythm. The highest reproducibility and individual steadiness featured cardiac reactions manifested by 2 waves of HR acceleration sequel to reflex-driven changes in the activity of the sympathetic and parasympathetic components of the autonomous nervous system. Data of the study attested the feasibility of testing the otolith-autonomous reflex responses in conscious monkeys with moderate stimulation in controlled experiments.
Badakva
A M
AM
Zalkind
D V
DV
Miller
N V
NV
Riazanskiĭ
S N
SN
D000818:Animals; D001341:Autonomic Nervous System / Q000502:physiology*; D004068:Digestive System Physiological Phenomena; D006339:Heart Rate / Q000502:physiology; D008253:Macaca mulatta / Q000502:physiology*; D008297:Male; D016065:Myoelectric Complex, Migrating / Q000502:physiology; D010037:Otolithic Membrane / Q000502:physiology*; D010812:Physical Stimulation / Q000379:methods; D012119:Respiration; D014851:Wakefulness / Q000502:physiology*