Automation of functional assays by flow injection fluorescence microscopy.
Bead-injection spectroscopy is a novel technique that uses immobilized eukaryotic cells on microbeads as a renewable biosensor for fluorescence microscopy. The use of a flow injection instrument allows fast functional assays that generate full kinetic characterization of a drug. Because the cell population is automatically replaced for each assay, variability is minimized, thus allowing greater accuracy.
Scampavia
L D
LD
Department of Chemistry, University of Washington, Box 351700, Seattle, WA 98195-1700, USA. scamp@u.washington.edu
Hodder
P S
PS
Lähdesmäki
I
I
Ruzicka
J
J
D001709:Biotechnology / Q000639:trends*; D018914:Cells, Immobilized; D005434:Flow Cytometry / Q000379:methods* / Q000639:trends*; D008856:Microscopy, Fluorescence / Q000379:methods* / Q000639:trends*; D008863:Microspheres