title: Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease.
abstract: Cerebrovascular disease and Alzheimer's disease commonly occur together in the elderly and each may contribute to dementia. Here we present evidence that cerebrovascular disease significantly worsens cognitive performance in the earliest stages of Alzheimer's disease.
authors.forename: M M
authors.initials: MM
authors.lastname: Esiri
authors.forename: Z
authors.initials: Z
authors.lastname: Nagy
authors.forename: M Z
authors.initials: MZ
authors.lastname: Smith
authors.forename: L
authors.initials: L
authors.lastname: Barnetson
authors.forename: A D
authors.initials: AD
authors.lastname: Smith
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000473:pathology; D001921:Brain / Q000473:pathology; D001931:Brain Mapping; D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000473:pathology; D015331:Cohort Studies; D015140:Dementia, Vascular / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009483:Neuropsychological Tests; D012307:Risk Factors