title: [Resting energy expenditure in cystic fibrosis].
abstract: OBJECTIVE
  Study of Resting Energy Expenditure (REE) by indirect calorimetry in patients with Cystic Fibrosis (CF), with the aim of determine its possible increase and its relationship with nutritional clinic and analitic parameters.
  
  
  METHODS
  Measurement of REE in 18 patients (11 female) with CF, without acute pulmonary exacerbation. Their age was between 5 years 3 months and 21 years 7 months. REE was expressed as kcal/day and as percentage of the predictive education of World Health Organization (WHO) for calculation of REE in function of gender, age and weight. It was also determined complete anthropometry and body composition derived (Siri), bioelectrical impedance, pulmonary function (FEV1 and FVC), chest X-ray (Score Chrispin) and blood sample (leucocits, VSG, IgM, vitamin A, C, E and serum lipids).
  
  
  RESULTS
  The mean REE was 1280 +/- 246 kcal/day. There was strong correlation with fat free mass (anthropometry) (r: 0.92; p < 0.0001) and with ratio height 2/resistance by bioelectric impedance (r: 0.89; p < 0.0001). If expressed as percentage of WHO education, REE was 104.2 +/- 9.8%. In chronic infected by Pseudomona sp. was 106.8 +/- 11.5% and 101.0 +/- 6.6 in no infected patients. REE was 102.9 +/- 6.4% in prepubertal subjects, 102.2 +/- 10.8% in pubertal, and 108.6 +/- 12.1 in postpubertal subjects. There was no significative correlation with nutritional status, but it was reported significative correlation with severity of pulmonary disease (FEV1: r: -0.58; p < 0.05. Score Chrispin: r: 0.62; p < 0.005). There was also significative correlation with ratio vitamin E/cholesterol (r: -0.60; p < 0.05), but not with another analitic parameters.
  
  
  CONCLUSIONS
  REE is strong correlated with fat free mass in patients with CF. The increased REE values over normal ones is related with severity of pulmonary disease. The decrease of ratio Vitamin E/cholesterol is also related with increase of REE.
authors.affiliation: Departamento de Pediatría, Hospital Clínico Universitario, Facultad de Medicina, Valladolid, España.
authors.forename: R
authors.initials: R
authors.lastname: Cancho Candela
authors.forename: M
authors.initials: M
authors.lastname: Alonso-Franch
authors.forename: C
authors.initials: C
authors.lastname: Calvo Romero
mesh_terms: D000293:Adolescent; D000328:Adult; D002151:Calorimetry; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000503:physiopathology*; D017097:Electric Impedance; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D008297:Male; D012146:Rest