title: [The interactions of functional systems at the homeostatic level in normal children and adolescents and in a radioecologically unfavorable environment].
abstract: In the article theoretical and application development of one of postulates of the Anokhin's theory of functional systems--the principle of multiparametric interaction is attempted in study of singularities of intersystem relationships of a number of leading functional homeostatic systems in a developing adolescent's organism living in radioecological unfavorable conditions and during rehabilitational procedures with application of interval dosed normobaric hypoxia. On the basis of a dynamic research of parameters cardiorespiratory and vegetative-humoral homeostasis is established, that the acclimatization of a children's organism to the factors of ecological and social risk in regions under small doses of radionuclides contamination is exhibited in reorganization of multiparametric relations of functional systems: a) increase of "rigidity" of intrasystem links separate cardiovascular effectors, b) of maximum activation sympathetic, pituitary-adrenal and pituitary-thyroid axes of a system stress-response, c) lack of intersystem consolidation of cardiorespiratory functional systems at a level of useful adaptive results. Thus character of interaction of homeostatic functional systems, their stability depend on personal combination of typological singularities in "the integral constitution" of the child-types of a vegetative regulation, somatic constitution, versions of emotional uneasiness. Principally important that it is revealed the capability of a correction in intersystem relations of homeostatic parameters, in particular, with the use of interval normobaric hypoxia of training (IHT). Hypoxic indorsements rendering the influence first of all through an exterior link of a functional system of breathing is carry on to recovery of integration of functional systems defining a homeostasis for children as at a level useful adaptive results. Thus the role initially high neurohumoral activity in achievement of best values cerebral, peripheral blood flow, lung ventilation is reduced, the contribution of separate effectors to security of physical functionality and aerobic capabilities of a children's organism "is equilibrated".
authors.affiliation: Research Institute of Normal Physiology named after P. K. Anokhin, Russian Academy of Medical Sciences.
authors.forename: O S
authors.initials: OS
authors.lastname: Glazachev
authors.forename: K V
authors.initials: KV
authors.lastname: Sudakov
mesh_terms: D000222:Adaptation, Physiological / Q000528:radiation effects; D000293:Adolescent; D000375:Aging / Q000502:physiology / Q000528:radiation effects; D001824:Body Constitution / Q000502:physiology; D002648:Child; D004463:Ecology; D004781:Environmental Exposure / Q000009:adverse effects*; D006706:Homeostasis / Q000502:physiology* / Q000528:radiation effects*; D006801:Humans; D011848:Radioactive Pollutants / Q000009:adverse effects*; D013598:Systems Theory
chemical_list: D011848:Radioactive Pollutants