title: A simple biofeedback digital data collection instrument to control ventilation during autonomic investigations.
abstract: Autonomic evaluation using the heart rate spectrum is sensitive to changes in breathing parameters, but few studies using this technique have controlled both the rate and depth of breathing. Fewer still have also measured or controlled inspiration and expiration times, or end-tidal carbon dioxide. This study describes the development of a digital instrument that can be used to alter tidal volume, ventilation rate and the time of inspiration and expiration with paced breathing visual templates displayed on a computer monitor. The digital instrument runs during data acquisition and displays the ventilatory signal from the subject superimposed on the paced breathing templates. Thus, adjustment of ventilatory parameters is achieved by matching the actual breathing signal to the target template. By regulating the ventilation rate and the tidal volume, end-tidal carbon dioxide could be increased or decreased in small increments. This instrument provided ventilatory control to investigate the effects on the heart rate spectrum of breathing depth, ventilation rate, end-tidal carbon dioxide and the time of expiration.
authors.affiliation: Department of Neuroscience, UMDNJ-New Jersey Medical School, Newark, NJ, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Davis
authors.forename: J E
authors.initials: JE
authors.lastname: Ottenweller
authors.forename: J
authors.initials: J
authors.lastname: LaManca
authors.forename: S S
authors.initials: SS
authors.lastname: Reisman
authors.forename: T W
authors.initials: TW
authors.lastname: Findley
authors.forename: B H
authors.initials: BH
authors.lastname: Natelson
mesh_terms: D001676:Biofeedback, Psychology / Q000295:instrumentation*; D002245:Carbon Dioxide / Q000032:analysis; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D012119:Respiration; D013990:Tidal Volume; D014630:Vagus Nerve / Q000502:physiology*
chemical_list: D002245:Carbon Dioxide