[The development of a technology for producing a new disinfecting agent with a universal spectrum of antimicrobial action].
The paper summarizes the findings of the physicochemical and potency of potassium fluoride peroxohydrate (PFP-1), a new Russian disinfecting agent having a universal spectrum of antimicrobial effects. It also summarizes the results of long-term practical use for the routine and final disinfection of rooms, sanitary engineering equipment, glassware, medical instruments against both sanitary indicative microorganisms, and actual pathogens of disease in infective and somatic hospitals, tuberculous dispensaries, sanatoria, schools, kindergartens, military hospitals, maternity houses of Russian different cities, towns, and localities. The paper presents comparative data on the mechanism of action of various modifications of PFP on microbial spores, on the stability of agents and their solutions during storage, on the damaging activity on the materials of the processed objects, on toxicological and ecological risks. The results of comparative studies of the bactericidal and sporicidal activities of the modifications PFP-1, PFP-2, PFP-3 confirmed that it is necessary to develop a procedure for preparing modifications containing high levels of hydrogen peroxide in the dry preparation and that they can be obtained at the pilot unit developed to prepare PFP-1 modifications.
Buianov
V V
VV
Nikol'skaia
V P
VP
Minaev
V A
VA
Titova
K V
KV
D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004202:Disinfectants / Q000737:chemistry / Q000494:pharmacology*; D004203:Disinfection / Q000379:methods; D004783:Environmental Microbiology; D005459:Fluorides / Q000737:chemistry / Q000494:pharmacology*; D006861:Hydrogen Peroxide / Q000737:chemistry / Q000494:pharmacology*; D017680:Potassium Compounds / Q000737:chemistry / Q000494:pharmacology*; D012996:Solutions; D013171:Spores, Bacterial / Q000187:drug effects
D004202:Disinfectants; D017680:Potassium Compounds; D012996:Solutions; C033320:potassium fluoride; D006861:Hydrogen Peroxide; D005459:Fluorides