title: [The beneficial cytotoxicity of antiseptics. The controversial paradox of cutaneous ulcer treatment].
abstract: The pathogeny of cutaneous ulcers is complex. The role of a critical bacterial contamination is controversial. The use of topical antibiotics is unwise, and that of antiseptics is still a matter of debate. Some authors contend that antiseptics mitigate wound healing through a toxic effect upon keratinocytes and fibroblasts. Other researchers bring forward sound arguments to support the concept of beneficial cytotoxicity of antiseptics in the treatment of chronic cutaneous ulcers.
authors.affiliation: Service de Dermatopathologie, Université de Liège.
authors.forename: J F
authors.initials: JF
authors.lastname: Hermanns
authors.forename: P
authors.initials: P
authors.lastname: Paquet
authors.forename: J E
authors.initials: JE
authors.lastname: Arrese
authors.forename: C
authors.initials: C
authors.lastname: Piérard-Franchimont
authors.forename: G E
authors.initials: GE
authors.lastname: Piérard
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000517:prevention & control; D002908:Chronic Disease; D006801:Humans; D012883:Skin Ulcer / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local