[The erythroblast antigen: a membrane protein bound to the erythroid form of the transferrin receptor?].
An interspecific marker of mammalian erythroid cells, which was called the erythroblast antigen, was identified in 1974, using polyclonal monospecific antibodies. Further studies have demonstrated the expression of this antigen in a variety of nonhemopoietic organs and tissues, which have the following common feature: they have a barrier location; that is, they are located at the boundary. It has been proposed that the erythroblast antigen participates directly or indirectly in the transport of various substances and specifically transport of iron. The present review deals with this topic.
Fuxon
V I
VI
Research Laboratory of Immunology and Cell Biology, College of Judea and Samaria, Ariel, Israel.
Kostyukov
M A
MA
Toder
V
V
Firer
M A
MA
D000818:Animals; D000941:Antigens / Q000097:blood*; D000954:Antigens, Surface / Q000097:blood; D000939:Epitopes / Q000097:blood; D004900:Erythroblasts / Q000276:immunology*; D015672:Erythroid Precursor Cells / Q000276:immunology*; D004920:Erythropoiesis / Q000276:immunology; D006801:Humans; D008565:Membrane Proteins / Q000097:blood*; D011485:Protein Binding; D011990:Receptors, Transferrin / Q000276:immunology*
D000941:Antigens; D000954:Antigens, Surface; D000939:Epitopes; D008565:Membrane Proteins; D011990:Receptors, Transferrin