Chorionic villus sampling prior to pregnancy termination, a tool for forensic paternity testing.
Chorionic villus sampling (CVS), prior to pregnancy termination (pre-termination CVS), is suggested as a tool for forensic paternity testing. Unlike the abortion material, which consists of ruptured tissues of fetal and maternal origin, extra-embryonic membranes obtained through CVS can provide an uncontaminated source of fetal tissue for genotyping. We discuss the possibility of confined placental mosaicism (CPM) and its implications on the polymerase chain reaction (PCR) based analyses of short tandem repeats (STRs) and the D1S80 loci.
Reshef
A
A
Forensic Biology Laboratory, Israel Police National Headquarters, Jerusalem, Israel.
Brauner
P
P
Shpitzen
M
M
Gallili
N
N
Marbach
A
A
Motro
U
U
Shmueli
E
E
Meiner
V
V
D000029:Abortion, Legal; D000293:Adolescent; D000483:Alleles; D002650:Child Abuse, Sexual; D015193:Chorionic Villi Sampling; D004247:DNA / Q000032:analysis; D005260:Female; D005838:Genotype; D006683:HLA-DQ Antigens / Q000032:analysis; D006801:Humans; D008297:Male; D018598:Minisatellite Repeats / Q000235:genetics; D010334:Paternity; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011902:Rape
D006683:HLA-DQ Antigens; D004247:DNA