title: Management of acute ischemic stroke.
abstract: Management of an acute ischemic stroke is multifaceted. Treatment in a specialized stroke unit reduces mortality and morbidity. Components of care include interventions to control or prevent medical or neurologic complications, rehabilitation, and initiations of therapies to forestall recurrent stroke. The key to modern treatment is the emergent administration of tissue plasminogen activator (rtPA). Thrombocyte treatment improves outcome when it is given within 3 hours of onset of stroke to carefully selected patients.
authors.affiliation: Division of Cerebrovascular Diseases, Department of Neurology, University of Iowa, Iowa City 52242, USA. harold-adams@uiowa.edu
authors.forename: E C
authors.initials: EC
authors.lastname: Leira
authors.forename: H P
authors.initials: HP
authors.lastname: Adams
mesh_terms: D000208:Acute Disease; D000368:Aged; D002545:Brain Ischemia / Q000188:drug therapy* / Q000517:prevention & control / Q000534:rehabilitation; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006757:Hospital Units; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D020521:Stroke / Q000188:drug therapy* / Q000517:prevention & control; D000071939:Stroke Rehabilitation; D015996:Survival Rate; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator