[The development of the slow potentiation of the population spike of a long-term nonstimulating input in rats in a state of anesthetic sleep].
Changes in synaptic efficacy of the medial perforant pathway were studied after the long-term deprivation of the afferent inputs in hippocampus of rats under chloral hydrate or urethane anesthesia. Evoked field potential population spikes and population excitatory postsynaptic potentials were recorded in the dentate gyrus. The long-term deprivation obtained by cessation of stimulation of the tested input for up to 4 hours resulted in an enhancement (up to 190%, p < 0.01) of the population spike amplitude.
Popov
V A
VA
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow.
Markevich
V A
VA
D000200:Action Potentials / Q000502:physiology; D000344:Afferent Pathways / Q000502:physiology; D000758:Anesthesia; D018686:Anesthetics, Intravenous; D000818:Animals; D002697:Chloral Hydrate; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D006624:Hippocampus / Q000502:physiology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012890:Sleep / Q000502:physiology*; D013997:Time Factors; D014520:Urethane
D018686:Anesthetics, Intravenous; D014520:Urethane; D002697:Chloral Hydrate