[Management of Werlhof disease in pregnancy complicated by diabetes mellitus type I].
We report on a 25-year old female in whom idiopathic thrombozytopenic purpura and diabetes type I existed at the same time in pregnancy. In this constellation we decided to treat her with intravenous immunoglobulins for five days and delivered her by caesarean after recovery of the maternal thrombozytes. While this proved to be an effective treatment for the mother with few adverse effects we saw severely low thrombozytopenia of the child requiring intensive postnatal care. A longterm treatment with immunoglobulins for about three weeks could be a possible treatment for the fetal as well as the maternal thrombozytopenia. Reports on this question do not yet exist.
Mollenkopf
A
A
Frauenklinik, St. Vincentiuskrankenhaus, Karlsruhe.
du Bois
A
A
Hummel
G
G
Meerpohl
H G
HG
D000328:Adult; D002585:Cesarean Section; D003131:Combined Modality Therapy; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000008:administration & dosage*; D007231:Infant, Newborn; D007328:Insulin / Q000008:administration & dosage*; D010976:Platelet Count; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy*; D011254:Pregnancy in Diabetics / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics; D011379:Prognosis; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics
C021306:IgG, sulfonated; D007074:Immunoglobulin G; D007328:Insulin