title: [A preclinical study of ximedone].
abstract: Pharmacotoxicological properties of ximedone, a new pyrimidine derivative, were studied experimentally on animals of various species. In the enteral regimen the drug had a favourable effect on thermal burns and postoperative cutaneous and gastric wounds. The results enabled to recommend ximedone for the clinical practice.
authors.affiliation: Military Medical Institute, Nizhnyi Novgorod Medical Academy, Kazan State Medical University.
authors.forename: S G
authors.initials: SG
authors.lastname: Izmaĭlov
authors.forename: S M
authors.initials: SM
authors.lastname: Gorbunov
authors.forename: G A
authors.initials: GA
authors.lastname: Izmaĭlov
authors.forename: I V
authors.initials: IV
authors.lastname: Zaikonnikova
authors.forename: V S
authors.initials: VS
authors.lastname: Reznik
authors.forename: N G
authors.initials: NG
authors.lastname: Abdrakhmanova
authors.forename: N G
authors.initials: NG
authors.lastname: Pashkurov
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Kedrin
authors.forename: M Kh
authors.initials: MKh
authors.lastname: Gerasimova
authors.forename: V N
authors.initials: VN
authors.lastname: Garaev
authors.forename: A G
authors.initials: AG
authors.lastname: Izmaĭlov
authors.forename: I V
authors.initials: IV
authors.lastname: Podushkina
authors.forename: G B
authors.initials: GB
authors.lastname: Evranova
authors.forename: A A
authors.initials: AA
authors.lastname: Muslinkin
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use* / Q000633:toxicity; D000818:Animals; D002056:Burns / Q000188:drug therapy*; D004353:Drug Evaluation, Preclinical; D006168:Guinea Pigs; D007928:Lethal Dose 50; D051379:Mice; D011183:Postoperative Complications / Q000517:prevention & control; D011743:Pyrimidines / Q000627:therapeutic use* / Q000633:toxicity; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D013530:Surgical Wound Infection / Q000188:drug therapy*; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000276:Adjuvants, Immunologic; D011743:Pyrimidines; C069705:xymedon