Intravascular hemolysis in aluminium phosphide poisoning.
Intravascular hemolysis is most often secondary to exposure to a variety of drugs or infections, and usually occurs in patients who are deficient in glucose-6-phosphate dehydrogenase (G-6-PD) enzyme. Aluminium phosphide, a fumigant widely used in India, has been reported to produce intravascular hemolysis in only one patient who also had concomitant G-6-PD deficiency. This report describes the occurrence of intravascular hemolysis with aluminium phosphide poisoning in a patient with normal G-6-PD levels. This is of significance as jaundice in patients with this poisoning is often attributed to hepatic damage alone.
Aggarwal
P
P
Department of Emergency Medicine, All India Institute of Medical Sciences, New Delhi.
Handa
R
R
Wig
N
N
Biswas
A
A
Saxena
R
R
Wali
J P
JP
D000328:Adult; D017607:Aluminum Compounds / Q000506:poisoning*; D006461:Hemolysis; D006801:Humans; D007194:India; D007565:Jaundice / Q000209:etiology; D008297:Male; D010575:Pesticides / Q000506:poisoning*; D010720:Phosphines / Q000506:poisoning*
D017607:Aluminum Compounds; D010575:Pesticides; D010720:Phosphines; C001864:aluminum phosphide