title: Chorionic villus sampling prior to pregnancy termination, a tool for forensic paternity testing.
abstract: Chorionic villus sampling (CVS), prior to pregnancy termination (pre-termination CVS), is suggested as a tool for forensic paternity testing. Unlike the abortion material, which consists of ruptured tissues of fetal and maternal origin, extra-embryonic membranes obtained through CVS can provide an uncontaminated source of fetal tissue for genotyping. We discuss the possibility of confined placental mosaicism (CPM) and its implications on the polymerase chain reaction (PCR) based analyses of short tandem repeats (STRs) and the D1S80 loci.
authors.affiliation: Forensic Biology Laboratory, Israel Police National Headquarters, Jerusalem, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Reshef
authors.forename: P
authors.initials: P
authors.lastname: Brauner
authors.forename: M
authors.initials: M
authors.lastname: Shpitzen
authors.forename: N
authors.initials: N
authors.lastname: Gallili
authors.forename: A
authors.initials: A
authors.lastname: Marbach
authors.forename: U
authors.initials: U
authors.lastname: Motro
authors.forename: E
authors.initials: E
authors.lastname: Shmueli
authors.forename: V
authors.initials: V
authors.lastname: Meiner
mesh_terms: D000029:Abortion, Legal; D000293:Adolescent; D000483:Alleles; D002650:Child Abuse, Sexual; D015193:Chorionic Villi Sampling; D004247:DNA / Q000032:analysis; D005260:Female; D005838:Genotype; D006683:HLA-DQ Antigens / Q000032:analysis; D006801:Humans; D008297:Male; D018598:Minisatellite Repeats / Q000235:genetics; D010334:Paternity; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011902:Rape
chemical_list: D006683:HLA-DQ Antigens; D004247:DNA