[Biological properties of primary HIV-1 isolates with varying serotype].
Russian HIV variants with common (rapid/high SI and slow/low NSI) and rare (slow/low SI and rapid/high NSI) phenotypes are described. SI variants demonstrate a higher p24 concentration level than serotype-independent NSI. The majority of SI variants belonging to A, B, and C serotypes were isolated from patients with mainly stage B3. At stages B2 and C2, when the majority of viruses are characterized by NSI phenotype, serotype D isolates are characterized only by SI phenotype. The spectrum of cell tropism was wide for all rapid/high strains and narrow for all slow/low ones.
Pashkova
T A
TA
Iaroslavtseva
N G
NG
Shchelkanov
M Iu
MIu
Papuashvili
M N
MN
Sakhuriia
I B
IB
Kornilaeva
G V
GV
Karamov
E V
EV
D000595:Amino Acid Sequence; D002460:Cell Line; D015699:HIV Envelope Protein gp120 / Q000737:chemistry; D015658:HIV Infections / Q000473:pathology / Q000821:virology*; D015497:HIV-1 / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D006801:Humans; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry; D010641:Phenotype; D017386:Sequence Homology, Amino Acid
D015699:HIV Envelope Protein gp120; C059762:HIV envelope protein gp120 (305-321); D010446:Peptide Fragments