title: Assessment of ethanol intake. Current tests and new assays on the horizon.
abstract: The number of tests used for the detection of ethanol ingestion is increasing. The field is rapidly moving beyond ethanol alone as a marker of ethanol intake. The combined measurement of carbohydrate deficient transferrin, FAEEs, 5-HTOL/5-HIAA, acetaldehyde adducts, and phosphatidylethanol may one day be used to approximate the time and amount of ethanol ingestion. The ultimate configuration of a panel of tests for monitoring ethanol intake awaits the results of studies that identify the clinical usefulness of each marker.
authors.affiliation: Department of Pathology, Massachusetts General Hospital, Boston 02114-2696, USA.
authors.forename: M
authors.initials: M
authors.lastname: Laposata
mesh_terms: D000079:Acetaldehyde / Q000032:analysis; D000435:Alcoholic Intoxication / Q000175:diagnosis*; D015415:Biomarkers / Q000032:analysis; D002849:Chromatography, Gas; D000431:Ethanol / Q000032:analysis*; D020404:Glycerophospholipids / Q000032:analysis; D006801:Humans; D006917:Hydroxytryptophol / Q000032:analysis; D007525:Isoelectric Focusing; D012463:Saliva / Q000737:chemistry; D014168:Transferrin / Q000031:analogs & derivatives / Q000032:analysis; D014822:Vitreous Body / Q000737:chemistry
chemical_list: D015415:Biomarkers; D020404:Glycerophospholipids; D014168:Transferrin; C056759:carbohydrate-deficient transferrin; C051521:phosphatidylethanol; D006917:Hydroxytryptophol; D000431:Ethanol; D000079:Acetaldehyde