[The effect of Cordafen (nifedipine) on endocytosis and bactericidal activity of polymorphonuclear granulocytes in peripheral blood].
The study was performed in patients taking Cordafen Polfa 30 mg a day. Just after three days of its administration, impaired basal metabolism of polymorphonuclear granulocytes in NBT test was found. After seven days of Cordafen use was demonstrated. Cordafen has no effect on oxygen metabolic activity in granulocytes stimulated by latex particles.
Misiewicz
A
A
VI Katedry i Kliniki Chorób Wewnetrznych Slaskiej Akademii Medycznej w Katowicach.
Dziewit
T
T
Radwan
K
K
Kowalczyk-Kowalska
M
M
Dutkiewicz
B
B
Sikora
I
I
D000328:Adult; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D004705:Endocytosis / Q000187:drug effects*; D006098:Granulocytes / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000494:pharmacology*; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects; D010587:Phagocytosis / Q000187:drug effects
D002121:Calcium Channel Blockers; D009543:Nifedipine