[Chronic myelogenous leukemia and blood stem cell transplantation].
Blood stem cell transplantation has become an important treatment modality for the complete cure of chronic myelogenous leukemia (CML). Favorable factors for the success of transplants are: (1) young patients, (2) treatment within 1 year of diagnosis, (3) CML in the chronic phase, (4) an allogeneic transplant from a matched sibling (BMT). Interferon treatment may be another effective therapy, however, it is not yet confirmed whether it can produce a complete cure or not. The most serious problem with BMT is considered to be early death. Informed consent and selection of treatment by the patient is very important.
Masaoka
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Osaka Medical Center for Cancer and Cardiovascular Disease, Japan.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007223:Infant; D007258:Informed Consent; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000401:mortality / Q000628:therapy*; D008875:Middle Aged; D015996:Survival Rate