title: Bone amyloidoma in a diabetic patient with morbid obesity.
abstract: Bone localisations of amyloidosis are rare, usually diffuse and associated with myeloma. We report the case of a patient with massive obesity complicated by diabetes, hypertension, sleep apnea and liver steatosis, who complained of rapidly worsening bilateral polyradiculalgia of the lower limbs. After sufficient weight loss made nuclear magnetic resonance imaging feasible, a spinal tumour was visualised on the 5th lumbar vertebra, extending to soft tissues. Total excision was performed, and pathological studies revealed an amyloid bone tumour with no evidence of myeloma.
authors.affiliation: Service d'Endocrinologie-Diabétologie-Nutrition, Hôpital Jean Verdier, Bondy, France.
authors.forename: P
authors.initials: P
authors.lastname: Miossec
authors.forename: B
authors.initials: B
authors.lastname: Lormeau
authors.forename: P
authors.initials: P
authors.lastname: Valensi
authors.forename: F
authors.initials: F
authors.lastname: Arthuis
authors.forename: J
authors.initials: J
authors.lastname: Amouroux
authors.forename: J R
authors.initials: JR
authors.lastname: Attali
mesh_terms: D000686:Amyloidosis / Q000150:complications* / Q000601:surgery; D001847:Bone Diseases / Q000150:complications* / Q000601:surgery; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000178:diet therapy; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000188:drug therapy; D005905:Glyburide / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000150:complications; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009765:Obesity; D009767:Obesity, Morbid / Q000150:complications* / Q000178:diet therapy; D012891:Sleep Apnea Syndromes / Q000150:complications; D015431:Weight Loss
chemical_list: D007004:Hypoglycemic Agents; D005905:Glyburide