title: The Concept of Docking/Protecting Groups in Biohydroxylation.
abstract: A general principle for biohydroxylation, in which time-consuming screening and enrichment techniques are avoided, is demonstrated by the introduction of a docking/protecting group into the substrate. This facilitates acceptance by the microorganism and allows the use of a narrow range of microorganisms, for example Beauveria bassiana ATTC 7159 (B. b.), for the hydroxylation of compounds with diverse structures. After the biohydroxylation, the docking/protecting group is removed (see scheme).
authors.affiliation: Spezialforschungsbereich F01 Biokatalyse, Institut für Organische Chemie der Technischen Universität Graz, Stremayrgasse 16, A-8010 Graz (Austria).
authors.initials: G
authors.lastname: Braunegg
authors.lastname: de Raadt A
authors.initials: S
authors.lastname: Feichtenhofer
authors.initials: H
authors.lastname: Griengl
authors.initials: I
authors.lastname: Kopper
authors.initials: A
authors.lastname: Lehmann
authors.initials: HJ
authors.lastname: Weber