title: Asymmetric synthesis of some substituted-3-phenyl prolines.
abstract: The asymmetric synthesis of carboxyphenyl prolines was performed according to Schöllkopf methodology, to prepare possible antagonists of the metabotropic glutamate receptor mGluR1.
authors.affiliation: Glaxo Wellcome S.p.A., Medicines Research Centre, Verona, Italy. fm20244@glaxowellcome.co.uk
authors.forename: F
authors.initials: F
authors.lastname: Micheli
authors.forename: R
authors.initials: R
authors.lastname: Di Fabio
authors.forename: C
authors.initials: C
authors.lastname: Marchioro
mesh_terms: D000818:Animals; D016466:CHO Cells; D006224:Cricetinae; D018756:GABA Antagonists / Q000138:chemical synthesis* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D011392:Proline / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D018094:Receptors, Metabotropic Glutamate / Q000037:antagonists & inhibitors*
chemical_list: D018756:GABA Antagonists; D018094:Receptors, Metabotropic Glutamate; D011392:Proline