Myelofibrosis: an unusual presentation of vitamin D-deficient rickets.
We present the case of a breast-fed 5-month-old infant who presented with pancytopenia, secondary to intense myelofibrosis during the winter months because of undiagnosed rickets. The patient responded to oral vitamin D with rapid resolution of symptoms. Secondary hyperparathyroidism was the probable cause of the myelofibrosis.


CONCLUSIONS
Although nutritional rickets remains a problem in developing countries, children in northern climates in industrialized countries may also be at risk. Rickets must be considered when assessing myelofibrosis in a very young child.
Stéphan
J L
JL
Paediatric Haematology and Oncology Unit, Hôpital Nord, Saint Etienne, F-42055, Cx02, France. jlstephan@infonie.fr
Galambrun
C
C
Dutour
A
A
Freycon
F
F
D006801:Humans; D007223:Infant; D008297:Male; D055728:Primary Myelofibrosis / Q000209:etiology*; D012279:Rickets / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D012307:Risk Factors; D014808:Vitamin D Deficiency / Q000150:complications*