Sex hormones and the female voice.
In the following, the authors examine the relationship between hormonal climate and the female voice through discussion of hormonal biochemistry and physiology and informal reporting on a study of 197 women with either premenstrual or menopausal voice syndrome. These facts are placed in a larger historical and cultural context, which is inextricably bound to the understanding of the female voice. The female voice evolves from childhood to menopause, under the varied influences of estrogens, progesterone, and testosterone. These hormones are the dominant factor in determining voice changes throughout life. For example, a woman's voice always develops masculine characteristics after an injection of testosterone. Such a change is irreversible. Conversely, male castrati had feminine voices because they lacked the physiologic changes associated with testosterone. The vocal instrument is comprised of the vibratory body, the respiratory power source and the oropharyngeal resonating chambers. Voice is characterized by its intensity, frequency, and harmonics. The harmonics are hormonally dependent. This is illustrated by the changes that occur during male and female puberty: In the female, the impact of estrogens at puberty, in concert with progesterone, produces the characteristics of the female voice, with a fundamental frequency one third lower than that of a child. In the male, androgens released at puberty are responsible for the male vocal frequency, an octave lower than that of a child. Premenstrual vocal syndrome is characterized by vocal fatigue, decreased range, a loss of power and loss of certain harmonics. The syndrome usually starts some 4-5 days before menstruation in some 33% of women. Vocal professionals are particularly affected. Dynamic vocal exploration by televideoendoscopy shows congestion, microvarices, edema of the posterior third of the vocal folds and a loss of its vibratory amplitude. The authors studied 97 premenstrual women who were prescribed a treatment of multivitamins, venous tone stimulants (phlebotonics), and anti-edematous drugs. We obtained symptomatic improvement in 84 patients. The menopausal vocal syndrome is characterized by lowered vocal intensity, vocal fatigue, a decreased range with loss of the high tones and a loss of vocal quality. In a study of 100 menopausal women, 17 presented with a menopausal vocal syndrome. To rehabilitate their voices, and thus their professional lives, patients were prescribed hormone replacement therapy and multi-vitamins. All 97 women showed signs of vocal muscle atrophy, reduction in the thickness of the mucosa and reduced mobility in the cricoarytenoid joint. Multi-factorial therapy (hormone replacement therapy and multi-vitamins) has to be individually adjusted to each case depending on body type, vocal needs, and other factors.
Abitbol
J
J
Ancien Interne, Ancien Chef de Clinique Assistant des Hôpitaux à la Faculté de Médecine de Paris, Oto-Rhino-Laryngologiste-Phoniatre-Chirurgie Laser-ENT, France. abitbolj@cybercable.fr
Abitbol
P
P
Abitbol
B
B
D000728:Androgens / Q000502:physiology*; D000818:Animals; D002369:Castration; D002835:Christianity / Q000266:history; D004967:Estrogens / Q000502:physiology*; D005260:Female; D049669:History, 16th Century; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D015186:Hominidae; D006801:Humans; D007830:Larynx / Q000033:anatomy & histology / Q000502:physiology; D008297:Male; D008593:Menopause / Q000502:physiology; D010036:Otolaryngology / Q000266:history; D010700:Phonetics; D011293:Premenstrual Syndrome / Q000150:complications; D011374:Progesterone / Q000502:physiology*; D012720:Severity of Illness Index; D013739:Testosterone / Q000502:physiology; D014831:Voice / Q000502:physiology*; D014832:Voice Disorders / Q000150:complications / Q000175:diagnosis; D014833:Voice Quality
D000728:Androgens; D004967:Estrogens; D013739:Testosterone; D011374:Progesterone