title: Unusual radiological presentation and rapid fatal progression of invasive pulmonary aspergillosis in an immunocompetent young patient.
abstract: Invasive aspergillosis occurs very rarely in immunocompetent hosts. We describe a 21-year-old female with no obvious immunosuppression or underlying lung disease, who presented with minimal symptoms and bilateral hilar prominence on chest X-ray. Invasive aspergillosis was diagnosed on an open lung biopsy. She deteriorated in the ensuing 2 weeks and died of a sudden massive haemoptysis. This initial radiological abnormality and the rapid clinical course of the disease in young immunocompetent patients have not been previously reported.
authors.affiliation: Department of Respiratory Medicine, Chest Diseases Hospital, Medical College, Trivandrum, Kerala, India. aims@md2.vsnl.net.in
authors.forename: K
authors.initials: K
authors.lastname: Parameswaran
authors.forename: M
authors.initials: M
authors.lastname: Joshi
authors.forename: P
authors.initials: P
authors.lastname: Ravindran
mesh_terms: D000328:Adult; D001228:Aspergillosis / Q000000981:diagnostic imaging* / Q000473:pathology; D001232:Aspergillus fumigatus; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006469:Hemoptysis / Q000209:etiology; D006801:Humans; D007121:Immunocompetence; D008168:Lung / Q000473:pathology; D008172:Lung Diseases, Fungal / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed