title: Alternative processing of the human and mouse raly genes(1).
abstract: A human homolog(RALY) of the mouse Raly gene was isolated and sequenced, and shown to encode a novel protein isoform containing a 16 amino acid in-frame insert in the variable region of the protein. Analysis of the corresponding region of the mouse Raly gene demonstrated that this novel protein isoform is also present in the mouse. Comparative analysis of RALY cDNA and EST sequences suggests the presence of additional alternatively processed RALY transcripts. As in the mouse, the human RALY gene is widely expressed as a 1.7-kb transcript.
authors.affiliation: Life Sciences Division, Oak Ridge National Laboratory, P.O. Box 2009, Oak Ridge, TN, USA.
authors.forename: I
authors.initials: I
authors.lastname: Khrebtukova
authors.forename: A
authors.initials: A
authors.lastname: Kuklin
authors.forename: R P
authors.initials: RP
authors.lastname: Woychik
authors.forename: E J
authors.initials: EJ
authors.lastname: Michaud
mesh_terms: D017398:Alternative Splicing; D000595:Amino Acid Sequence; D000818:Animals; D018076:DNA, Complementary / Q000737:chemistry; D020224:Expressed Sequence Tags; D034482:Heterogeneous-Nuclear Ribonucleoprotein Group C; D006801:Humans; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D020033:Protein Isoforms / Q000737:chemistry; D012313:RNA / Q000737:chemistry; D016601:RNA-Binding Proteins / Q000737:chemistry / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012261:Ribonucleoproteins / Q000737:chemistry / Q000235:genetics*; D016415:Sequence Alignment; D013737:Testis / Q000378:metabolism
chemical_list: D018076:DNA, Complementary; D034482:Heterogeneous-Nuclear Ribonucleoprotein Group C; D020033:Protein Isoforms; C088730:RALY protein, human; D016601:RNA-Binding Proteins; C484219:Raly protein, mouse; D012261:Ribonucleoproteins; D012313:RNA