[Cerebral agyria-pachygyria in a child with Werdnig-Hoffmann disease].
Werdnig-Hoffmann disease refers to the severe infantile form of anterior horn cell degeneration. We report an association between Werdnig-Hoffmann disease and agyria-pachygyria. Examples of anterior horn cell disease with lesions in the central nervous system (notably thalamus and cerebellum) have been considered unusual "variants" of Werdnig-Hoffmann disease. This association between Werdnig-Hoffmann disease and agyria-pachygyria has, to our knowledge, never been described.
Cneude
F
F
Service de Pédiatrie, Hôpital Saint-Antoine, Lille.
Sukno
S
S
Boidein
F
F
Dehouck
M B
MB
Bourlet
A
A
Vittu
G
G
D002540:Cerebral Cortex / Q000002:abnormalities* / Q000473:pathology*; D002648:Child; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014897:Spinal Muscular Atrophies of Childhood / Q000473:pathology*