Grading of renal cell carcinoma.
Recognition of the prognostic utility of renal cell carcinoma grading is not a recent development. Most pathologists in the United States use the Fuhrman grading system; however, this system is fraught with limitations and controversies. The Fuhrman grading system makes initial sense and seems simple to apply; however, it is hampered by several limitations, the foremost being that there is no consensus on the prognostic significance of the different grades of renal cell carcinoma.
Goldstein
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Department of Anatomic Pathology, William Beaumont Hospital, Royal Oak, Michigan, USA. NSGJSG@aol.com
D002292:Carcinoma, Renal Cell / Q000473:pathology*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D011379:Prognosis