title: Evidence for preganglionic pupillary involvement in superficial siderosis.
abstract: A 36-year-old man presented with spinal myoclonus, ataxia, hearing loss, and unilateral pupillary dilation. MRI demonstrated hemosiderin deposition along the superficial surfaces of the brain, brainstem, cerebellum, and spine. The pupillary changes were localized to the preganglionic oculomotor nerve. In contrast to vasculopathic oculomotor nerve palsies, superficial siderosis may cause selective involvement of the superficially located pupillary fibers.
authors.affiliation: Department of Neurology, Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.
authors.forename: V S
authors.initials: VS
authors.lastname: Pelak
authors.forename: S L
authors.initials: SL
authors.lastname: Galetta
authors.forename: R I
authors.initials: RI
authors.lastname: Grossman
authors.forename: J J
authors.initials: JJ
authors.lastname: Townsend
authors.forename: N J
authors.initials: NJ
authors.lastname: Volpe
mesh_terms: D000328:Adult; D001339:Autonomic Fibers, Preganglionic / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011680:Pupil / Q000502:physiology*; D012806:Siderosis / Q000473:pathology* / Q000503:physiopathology