title: Computerized auscultation applied to irritable bowel syndrome.
abstract: The purpose of this study was to investigate the potential of a computerized auscultation method for providing an objective, quantitative measure characteristic of irritable bowel syndrome. Bowel sounds from irritable bowel patients and normal controls were digitized using an electronic stethoscope. Computerized analysis indicated that the character of the bowel sounds did not differ significantly between groups. However, the fasting sound-to-sound interval was significantly different between groups (1931 +/- 365 msec for normals and 452 +/- 35 msec for the irritable bowel group; P = 0.0001). Using the sound-to-sound interval as a test for irritable bowel syndrome, the cutoff value of 640 msec resulted in a sensitivity of 89%, and a specificity of 100%. We conclude that computerized analysis of bowel sounds has the potential to be a noninvasive, quantitative, and objective test providing positive criteria in the diagnosis of irritable bowel syndrome.
authors.affiliation: Western Research Company, Inc., Tucson, Arizona 85745, USA.
authors.forename: B L
authors.initials: BL
authors.lastname: Craine
authors.forename: M
authors.initials: M
authors.lastname: Silpa
authors.forename: C J
authors.initials: CJ
authors.lastname: O'Toole
mesh_terms: D001314:Auscultation; D003109:Colonic Diseases, Functional / Q000175:diagnosis* / Q000503:physiopathology; D003936:Diagnosis, Computer-Assisted; D005215:Fasting; D005260:Female; D006801:Humans; D007422:Intestines / Q000503:physiopathology; D008297:Male; D012680:Sensitivity and Specificity; D013016:Sound; D013997:Time Factors