title: Relation between infarct artery patency at late angiography after acute myocardial infarction and signal-averaged electrocardiography.
abstract: The angiograms of 89 patients were reviewed from the LATE Ancillary Study (randomized trial of recombinant tissue plasminogen activator vs placebo in patients with symptom onset after 6 hours of myocardial infarction) to determine patency of the infarct-related artery (IRA). In the occluded IRA group (n = 35), the incidence of signal-averaged electrocardiographic abnormality (fQRS > 120 ms) was significantly higher (p = 0.04), the filtered QRS duration was significantly longer (p = 0.007), and the V40 was significantly shorter (p = 0.02), compared with the patent IRA group (n = 54).
authors.affiliation: Department of Medicine, St. Luke's-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York 10025, USA.
authors.forename: S
authors.initials: S
authors.lastname: Chandrasekaran
authors.forename: J S
authors.initials: JS
authors.lastname: Hochman
authors.forename: J N
authors.initials: JN
authors.lastname: Slater
authors.forename: A M
authors.initials: AM
authors.lastname: Palazzo
authors.forename: C D
authors.initials: CD
authors.lastname: Morgan
authors.forename: J S
authors.initials: JS
authors.lastname: Steinberg
mesh_terms: D000328:Adult; D000368:Aged; D017023:Coronary Angiography / Q000187:drug effects; D016757:Death, Sudden, Cardiac / Q000209:etiology / Q000517:prevention & control; D004562:Electrocardiography / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D011446:Prospective Studies; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D012815:Signal Processing, Computer-Assisted; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D014693:Ventricular Fibrillation / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality
chemical_list: D010959:Tissue Plasminogen Activator