Mouse ear edema modulation by different propolis ethanol extracts.
The anti-inflammatory activity of 14 commercial ethanol extracts of propolis were evaluated, using a mouse ear inflammation model induced by arachidonic acid. Indometacin was also assayed as standard anti-inflammatory agent. Different activities were observed and discussed. This model could be used to assess the anti-inflammatory quality of propolis extracts and facilitate their posological usage on skin edema resulting from wounds.
Menezes
H
H
Department of Biochemistry and Microbiology, Universidade Estadual Paulista, Rio Claro, São Paulo State, Brazil. hermes@rc.unesp.br
Alvarez
J M
JM
Almeida
E
E
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D016718:Arachidonic Acid; D004431:Ear, External / Q000473:pathology; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology; D000431:Ethanol; D005260:Female; D007213:Indomethacin / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C; D011429:Propolis / Q000627:therapeutic use*; D012997:Solvents
D000894:Anti-Inflammatory Agents, Non-Steroidal; D012997:Solvents; D016718:Arachidonic Acid; D000431:Ethanol; D011429:Propolis; D007213:Indomethacin