title: Controls in patterning and diversification of somatic muscles during Drosophila embryogenesis.
abstract: Recent genetic studies in Drosophila have provided important insights into the pathways determining the formation and diversification of body wall muscles. These pathways control a progressive subdivision of the mesoderm, ultimately leading to the specification of individual cells, the muscle founders, which are endowed with genetic programs capable of generating distinct muscle fibers. A network of activities of transcriptional regulators, signaling pathways, and lineage genes is beginning to emerge which controls successive steps of this muscle patterning and differentiation process.
authors.affiliation: Department of Biochemistry and Molecular Biology Mount Sinai School of Medicine Box 1020, New York, New York 10029, USA.
authors.forename: M
authors.initials: M
authors.lastname: Frasch
mesh_terms: D000818:Animals; D019521:Body Patterning; D002455:Cell Division; D004330:Drosophila / Q000196:embryology* / Q000235:genetics; D008648:Mesoderm; D009132:Muscles / Q000196:embryology*