title: Platelet-activating factor concentrations in healthy and septic neonates.
abstract: Platelet-activating factor levels were measured in nine preterm infants with Klebsiella pneumonia septicaemia, eight healthy preterm infants of similar gestational age and ten healthy full-term infants of the same postnatal age at sampling. The platelet-activating factor levels of the healthy preterm and term groups did not differ significantly, but were elevated compared to the other two groups in the septic preterm infants (P < 0.01). Platelet-activating factor levels increase upon stimulation by Gram negative bacteraemia and are a important mediator of neonatal sepsis.
authors.affiliation: Ege University Faculty of Medicine, Department of Paediatrics, Bornova, Izmir, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Kültürsay
authors.forename: M
authors.initials: M
authors.lastname: Kantar
authors.forename: M
authors.initials: M
authors.lastname: Akisü
authors.forename: A
authors.initials: A
authors.lastname: Hüseyinov
authors.forename: I
authors.initials: I
authors.lastname: Coker
mesh_terms: D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D007234:Infant, Premature / Q000097:blood; D010972:Platelet Activating Factor / Q000032:analysis*; D012016:Reference Values; D018805:Sepsis / Q000097:blood*
chemical_list: D010972:Platelet Activating Factor