title: [Concentrating dopamine in liposomes using transmembrane gradient of ammonium sulfate].
abstract: The active loading of liposomes from egg phosphatidylcholine and cholesterol with dopamine using an ammonium sulfate gradient was studied. Our conditions allowed the enrichment of the monolamellar liposomes with 90% dopamine added to the medium and, thus, considerably improve the dopamine/lipid ratio. Dopamine-containing liposomes with tocopherol in their lipid bilayer were shown to be stable for 3 weeks.
authors.affiliation: Lomonosov State Academy of Fine Chemical Technology, Moscow, Russia.
authors.forename: I V
authors.initials: IV
authors.lastname: Zhigal'tsev
authors.forename: S N
authors.initials: SN
authors.lastname: Kolomeĭchuk
authors.forename: A P
authors.initials: AP
authors.lastname: Kaplun
authors.forename: V G
authors.initials: VG
authors.lastname: Kucherianu
authors.forename: V V
authors.initials: VV
authors.lastname: Iurasov
authors.forename: V I
authors.initials: VI
authors.lastname: Shvets
mesh_terms: D000645:Ammonium Sulfate / Q000737:chemistry*; D002784:Cholesterol / Q000737:chemistry; D004298:Dopamine / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry; D008081:Liposomes; D010713:Phosphatidylcholines / Q000737:chemistry; D014810:Vitamin E / Q000737:chemistry
chemical_list: D008051:Lipid Bilayers; D008081:Liposomes; D010713:Phosphatidylcholines; D014810:Vitamin E; D002784:Cholesterol; D000645:Ammonium Sulfate; D004298:Dopamine