Surface photograft polymerization on segmented polyurethane using the iniferter technique.
A segmented polyurethane (SPU) film was chloromethylated and subsequently dithiocarbamated. The treated films were immersed in solutions containing poly(ethylene glycol) methacrylate (PEGMA) or N, N-dimethyl-acryl amide (DMAAm) and irradiated with ultraviolet (UV) light. The resultant surfaces were highly wettable with water. The surface chemical compositions, as determined by X-ray photoelectron spectroscopy, indicated that surface graft polymerization, initiated from surface-derivatized dithiocarbamate, had occurred and had altered the surface properties and the composition of SPU. The platelet adhesion test using platelet-rich plasma showed minimal adhesion for the poly(PEGMA)-grafted surface, followed by the poly(DMAAm)-grafted surface.
Lee
H J
HJ
Department of Bioengineering, National Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565, Japan.
Matsuda
T
T
D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology; D019281:Dimerization; D004285:Dogs; D010974:Platelet Aggregation / Q000187:drug effects; D011108:Polymers / Q000737:chemistry; D011140:Polyurethanes / Q000737:chemistry* / Q000494:pharmacology
D001672:Biocompatible Materials; D011108:Polymers; D011140:Polyurethanes