title: Addition of fat to the diets of lactating sows: II. Effects on hormone-sensitive lipase activity, energy mobilization in response to epinephrine, and plasma insulin and glucose concentrations.
abstract: Four experiments were conducted to determine the effects of dietary fat on lipolysis in lactating sows. In Exp. 1, a 6 x 6 Latin square was used to determine the optimal dosage of epinephrine for use in a subsequent epinephrine challenge. Peak concentrations of plasma glucose and response area increased linearly (P < .10) with epinephrine dosage. However, plasma NEFA peak and response area were quadratically affected (P < .05 and .06, respectively) by epinephrine dosage, with a minimum NEFA peak concentration observed at .4 microg/kg and a maximum at 1.6 microg/kg. In Exp. 2, the effect of dietary tallow on the response to epinephrine infusion (1.6 microg/kg BW) was examined. No differences (P > .10) between treatments were observed in NEFA, glycerol, or peak concentrations of plasma glucose following epinephrine administration. In Exp. 3, the effect of dietary fat on hormone-sensitive lipase activity was examined. Sows (n = 36) were fed diets containing either 0 or 10% added tallow. Hormone-sensitive lipase activity on d 28 of lactation was increased by the addition of tallow to the diet (P = .06). No effect of dietary tallow was observed on hormone-sensitive lipase activity of adipose tissue on d 21 of lactation (P > .10) in Exp. 3 (n = 16 sows) and Exp. 4 (n = 30 sows). In summary, diets containing 10% added tallow did not alter the rate of lipolysis, as measured by exogenous epinephrine challenge, in adipose tissue of lactating sows.
authors.affiliation: Department of Animal Science, University of Nebraska, Lincoln 68583-0908, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Tilton
authors.forename: P S
authors.initials: PS
authors.lastname: Miller
authors.forename: A J
authors.initials: AJ
authors.lastname: Lewis
authors.forename: D E
authors.initials: DE
authors.lastname: Reese
authors.forename: P M
authors.initials: PM
authors.lastname: Ermer
mesh_terms: D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D004041:Dietary Fats / Q000494:pharmacology*; D004734:Energy Metabolism / Q000187:drug effects; D004837:Epinephrine / Q000494:pharmacology*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D007328:Insulin / Q000097:blood*; D007774:Lactation; D008098:Litter Size; D002787:Sterol Esterase / Q000378:metabolism*; D013552:Swine / Q000378:metabolism*
chemical_list: D001786:Blood Glucose; D004041:Dietary Fats; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D002787:Sterol Esterase; D004837:Epinephrine