title: Abdominal aortic aneurysm. Detection of multilevel vascular pathology by time-resolved multiphase 3D gadolinium MR angiography: initial report.
abstract: OBJECTIVE
  To evaluate multiphasic 3D gadolinium-enhanced magnetic resonance angiography (3D-Gd-MRA) for detection of vascular pathology at multiple levels of the aorta and iliac arteries.
  
  
  METHODS
  In 18 patients with abdominal aortic aneurysm (n = 13), dissection (n = 3), or both (n = 2), multiphase 3D-Gd-MRA was performed acquiring five consecutive (6.8 seconds) 3D data sets in a single breath-hold. In each of the five time-resolved phases, vessel visibility of the abdominal aortic branches and iliac arteries was assessed. The extent of vessel involvement by the aneurysm or dissection seen on multiphase 3D-Gd-MRA was compared with standard imaging and surgical findings. Digital subtraction angiography was available for comparison in 4 cases, CT angiography in 10 cases.
  
  
  RESULTS
  Due to the delayed filling of the aortic aneurysm, the proximal aortic branches and the aneurysm neck demonstrated an inversely related enhancement compared with the distal abdominal and iliac vessels (P < 0.001). Review of all five phases of multiphase 3D-Gd-MRA allowed optimal visualization of each vessel segment without any artifacts due to parenchymal or venous overlay. In dissections, review of three phases was required (P < 0.001) for diagnostic evaluation of the true and false lumens. Substantially more vessel involvement was detected on multiphase 3D-Gd-MRA; this was surgically confirmed in 10 of 11 cases and affected therapy management in 11 of 18 cases.
  
  
  CONCLUSIONS
  Multiphase 3D-Gd-MRA is a convenient, robust, and safe technique for presurgical anatomic mapping of complex aortic aneurysms and dissections.
authors.affiliation: Department of Radiology, German Cancer Research Center, Heidelberg, Germany.
authors.forename: S O
authors.initials: SO
authors.lastname: Schoenberg
authors.forename: C
authors.initials: C
authors.lastname: Wunsch
authors.forename: M V
authors.initials: MV
authors.lastname: Knopp
authors.forename: M
authors.initials: M
authors.lastname: Essig
authors.forename: H
authors.initials: H
authors.lastname: Hawighorst
authors.forename: G
authors.initials: G
authors.lastname: Laub
authors.forename: M R
authors.initials: MR
authors.lastname: Prince
authors.forename: J R
authors.initials: JR
authors.lastname: Allenberg
authors.forename: G
authors.initials: G
authors.lastname: Van Kaick
mesh_terms: D000784:Aortic Dissection / Q000473:pathology; D017544:Aortic Aneurysm, Abdominal / Q000473:pathology*; D003287:Contrast Media / Q000008:administration & dosage; D019786:Gadolinium DTPA / Q000008:administration & dosage; D006801:Humans; D007083:Iliac Artery; D018810:Magnetic Resonance Angiography / Q000379:methods*; D011856:Radiographic Image Enhancement
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA