title: Angiographic changes in uterine cervical cancer during the course of transarterial infusion chemotherapy.
abstract: OBJECTIVE
  To assess the correlation between angiographic findings, tumor stage, tumor size, histological type, and the effect of transcatheter arterial infusion (TAI) chemotherapy in patients with uterine cervical cancer.
  
  
  METHODS
  Thirty-three patients with untreated cervical cancer underwent two cycles of TAI. Changes in angiographic findings and other clinical and imaging data were assessed using the X2 test, multivariate analysis, and the two-sample t-test.
  
  
  RESULTS
  The group with parametric involvement included more patients with hypervascular tumors (21/24) than the group with no parametric involvement (0/5) (p < 0.001). Multivariate analysis revealed no correlation between initial tumor size, histology, or angiographic pattern and the effect of TAI.
  
  
  CONCLUSIONS
  The angiographic patterns seen in cervical cancer correlated with tumor stage. However, neither angiographic findings nor other clinical features predicted the effect of TAI.
authors.affiliation: Department of Radiology, Kyoto University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Saitoh
authors.forename: Y
authors.initials: Y
authors.lastname: Nagata
authors.forename: M
authors.initials: M
authors.lastname: Mitsumori
authors.forename: M
authors.initials: M
authors.lastname: Kokubo
authors.forename: M
authors.initials: M
authors.lastname: Hiraoka
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D000328:Adult; D000368:Aged; D000792:Angiography; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D002406:Catheterization, Peripheral; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009367:Neoplasm Staging; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging / Q000473:pathology; D012189:Retrospective Studies; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents