Selective B-wave reduction with congenital cataract in neurofibromatosis-2.
OBJECTIVE
To electroretinographically evaluate a case of neurofibromatosis-2 (NF-2).


METHODS
Case report and literature review.


METHODS
A 29-year-old man diagnosed with NF-2.


METHODS
Electroretinography (ERG), ophthalmic biomicroscopy, and ultrasound examination results were reviewed.


RESULTS
The ERG of one eye showed selective reduction of b-wave amplitudes. A characteristic posterior subcapsular lens opacity also was observed in that eye. A dense white congenital cataract and a retinal detachment were detected in the fellow eye.


CONCLUSIONS
An inner retinal dysfunction, as evidenced by an abnormal ERG, may occur in NF-2. Further ERG evaluation of other patients with NF-2 is indicated to determine possible associations between NF-2 and selective b-wave reduction.
Tong
J T
JT
Jules Stein Eye Institute, University of California Los Angeles School of Medicine, USA.
Bateman
J B
JB
D000328:Adult; D002386:Cataract / Q000150:complications / Q000151:congenital*; D004596:Electroretinography; D005094:Exophthalmos / Q000150:complications; D006801:Humans; D008297:Male; D016518:Neurofibromatosis 2 / Q000503:physiopathology*; D012160:Retina / Q000503:physiopathology*; D012163:Retinal Detachment / Q000150:complications* / Q000503:physiopathology