New directions in the prevention of adhesion in laparoscopic surgery.
The aim of this review is to appraise critically the literature over the past year with respect to new developments in adhesion prevention strategies. The majority of the work continues to be focused on animal models, and interest continues into the usage of heterologous barriers, which are increasingly derived from or related to hyaluronic acid. The recent trend has been to develop barriers that are not only effective but also technically easy to use for the laparoscopic surgeon--hence the development of barrier gels. It is only through the development of these user-friendly barriers that many laparoscopic surgeons will be willing to incorporate these important preventative measures into their busy daily practice. Routine usage of adhesion prevention measures will ultimately reduce patient morbidity and mortality and relieve the burden on health service provision.
Panay
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Royal Hospital's Fertility Centre at St Bartholomew's Hospital, London, UK.
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D000894:Anti-Inflammatory Agents, Non-Steroidal; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid; D010535:Laparoscopy / Q000592:standards*; D010532:Peritoneal Diseases / Q000517:prevention & control*; D011728:Pyridones; D000267:Tissue Adhesions / Q000517:prevention & control
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011728:Pyridones; D006820:Hyaluronic Acid; C093844:pirfenidone