Calretinin-immunoreactive neurons in rostral migratory stream: neuronal differentiation.
The purpose of the present study was to examine immunohistochemically the expression of nestin and polysialylated neural cell adhesion molecule in calretinin-immunoreactive neurons of the rostral migratory stream, the restricted pathway through which neuronal precursor cells migrate towards the olfactory bulb. Using mirror sectioning, calretinin-immunoreactive neurons of the rostral migratory stream were shown to co-express nestin (20.8%) and polysialylated neural cell adhesion molecule (61.8%). The results show that calretinin-immunoreactive neurons in the rostral migratory stream still express immature neural and neuronal phenotypes.
Kato
T
T
Department of Anatomy, Shinshu University School of Medicine, Matsumoto, Japan.
Yokouchi
K
K
Li
Z
Z
Fukushima
N
N
Kawagishi
K
K
Moriizumi
T
T
D000818:Animals; D064032:Calbindin 2; D002454:Cell Differentiation; D002465:Cell Movement; D005260:Female; D007150:Immunohistochemistry; D007381:Intermediate Filament Proteins / Q000378:metabolism; D008722:Methods; D019158:N-Acetylneuraminic Acid / Q000378:metabolism; D009419:Nerve Tissue Proteins; D064231:Nestin; D019006:Neural Cell Adhesion Molecules / Q000378:metabolism; D009474:Neurons / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D064030:S100 Calcium Binding Protein G / Q000378:metabolism*
C576512:Calb2 protein, rat; D064032:Calbindin 2; D007381:Intermediate Filament Proteins; D009419:Nerve Tissue Proteins; C577486:Nes protein, rat; D064231:Nestin; D019006:Neural Cell Adhesion Molecules; D064030:S100 Calcium Binding Protein G; D019158:N-Acetylneuraminic Acid