title: Effectiveness of combining atypical antipsychotics and psychosocial rehabilitation in a community mental health center setting.
abstract: This article presents a consecutive case series of 70 patients treated with olanzapine, case management, and psychosocial rehabilitation in a community mental health setting. This group demonstrated highly significant improvement on all analyzed measures of symptoms and psychosocial function at 6-month follow-up. These findings suggest that results of efficacy studies of olanzapine will generalize to the community mental health setting. Furthermore, prescribing olanzapine in combination with case management and rehabilitation yields positive functional outcomes.
authors.affiliation: The Mental Health Center of Greater Manchester and Dartmouth Medical School, New Hampshire 03101, USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Noordsy
authors.forename: C
authors.initials: C
authors.lastname: O'Keefe
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001569:Benzodiazepines; D010054:Brief Psychiatric Rating Scale / Q000706:statistics & numerical data; D019090:Case Management / Q000706:statistics & numerical data; D002986:Clinical Trials as Topic; D003155:Community Mental Health Centers / Q000458:organization & administration; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000077152:Olanzapine; D010865:Pilot Projects; D010890:Pirenzepine / Q000031:analogs & derivatives / Q000627:therapeutic use; D015397:Program Evaluation; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D012046:Rehabilitation / Q000379:methods; D012559:Schizophrenia / Q000188:drug therapy* / Q000534:rehabilitation*; D012565:Schizophrenic Psychology; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D001569:Benzodiazepines; D010890:Pirenzepine; D000077152:Olanzapine