A word of caution in extrapolating the spinal cord protective effects of memantine obtained in a rabbit model under ketamine anesthesia.
Miyamoto
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TA
Miyamoto
K J
KJ
D000778:Anesthetics, Dissociative / Q000008:administration & dosage*; D000818:Animals; D001812:Blood-Brain Barrier; D001831:Body Temperature / Q000502:physiology; D004195:Disease Models, Animal; D004947:Esophagus; D019054:Evoked Potentials, Motor / Q000187:drug effects; D018691:Excitatory Amino Acid Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D007262:Infusions, Intravenous; D007649:Ketamine / Q000008:administration & dosage*; D008559:Memantine / Q000008:administration & dosage / Q000627:therapeutic use*; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D011817:Rabbits; D012007:Rectum; D013116:Spinal Cord / Q000187:drug effects*; D020760:Spinal Cord Ischemia / Q000517:prevention & control; D013997:Time Factors
D000778:Anesthetics, Dissociative; D018691:Excitatory Amino Acid Antagonists; D018696:Neuroprotective Agents; D007649:Ketamine; D008559:Memantine