title: Treatment of severe orthopedic infections.
abstract: Severe infections are uncommon following orthopedic surgery, yet they can be frustrating for the veterinarian and owner to treat and can result in devastating consequences for the patient. This article reviews the common causes for postoperative infection, reviews established treatment, and introduces newer methods for treatment and control. A thorough understanding of the pathogenesis, application of appropriate diagnostic procedures, the institution of aggressive treatment regimens, with adherence to established principles, will often result in satisfactory outcomes even with severe orthopedic infections. For those more refractory to treatment, the use of newer treatment methods, specifically locally implantable materials for sustained release of antimicrobials can improve success in the treatment of these more difficult cases.
authors.affiliation: Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, USA.
authors.forename: W S
authors.initials: WS
authors.lastname: Dernell
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001424:Bacterial Infections / Q000628:therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000628:therapy*; D004285:Dogs; D010019:Osteomyelitis / Q000628:therapy / Q000662:veterinary*; D019904:Polymethyl Methacrylate
chemical_list: D000900:Anti-Bacterial Agents; D019904:Polymethyl Methacrylate