title: Clinical manifestations of a sometimes silent disease.
abstract: Although the host tissue response to debris is rarely symptomatic, the clinical manifestations of implant wear are profound. Even the most experienced orthopedic surgeon can be challenged in managing this sometimes silent disease.
authors.affiliation: Anderson Orthopaedic Research Institute, Alexandria, VA 22306, USA.
authors.forename: G A
authors.initials: GA
authors.lastname: Engh
authors.forename: D J
authors.initials: DJ
authors.lastname: Ammeen
mesh_terms: D019643:Arthroplasty, Replacement / Q000009:adverse effects*; D006622:Hip Prosthesis; D006801:Humans; D007593:Joint Instability / Q000209:etiology; D007720:Knee Prosthesis; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000175:diagnosis; D018570:Risk Assessment; D013314:Stress, Mechanical