title: Pulsed dye laser therapy for sun damaged skin.
abstract: OBJECTIVE
  The objective of this study was to evaluate the effectiveness of the pulsed dye laser (585 nm, 450 ms) in the treatment of sun induced wrinkles.
  
  
  METHODS
  Patients had one pulsed dye laser (585 nm) treatment. The treated areas were assessed by the following methods: grading of skin wrinkles at 6 weeks, 12 weeks, and 6-14 months after treatment by blinded observers and by light and electron microscopy.
  
  
  METHODS
  An ambulatory care center at Abbott Northwestern Hospital (ANH) and the Laser & Skin Surgery Center of Northern California (LSSCNC).
  
  
  METHODS
  Twenty patients were treated, half with mild to moderate and half with moderate to severe sun induced skin wrinkles.
  
  
  RESULTS
  At last follow up 90% (9/10) of the mild to moderate wrinkles and 40% (4/10) of the treated patients with moderate to severe wrinkles had clinically observable improvement in their sun induced skin wrinkles. Histologic examinations of the treated areas showed a superficial dermal band of well organized elastin and collagen fibers replacing pre-treatment elastic tissue. Increased cellularity and mucin deposition was consistent with dermal collagen remodeling.
authors.affiliation: University of Minnesota, Skin Specialists Inc., Abbott Northwestern Hospital Laser Center, Minneapolis, Minnesota 55414, USA.
authors.forename: B D
authors.initials: BD
authors.lastname: Zelickson
authors.forename: S L
authors.initials: SL
authors.lastname: Kilmer
authors.forename: E
authors.initials: E
authors.lastname: Bernstein
authors.forename: V A
authors.initials: VA
authors.lastname: Chotzen
authors.forename: J
authors.initials: J
authors.lastname: Dock
authors.forename: D
authors.initials: D
authors.lastname: Mehregan
authors.forename: C
authors.initials: C
authors.lastname: Coles
mesh_terms: D000328:Adult; D000368:Aged; D003094:Collagen / Q000648:ultrastructure; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000648:ultrastructure; D015595:Skin Aging
chemical_list: D003094:Collagen