title: Pancreatic disorders associated with anomalous pancreaticobiliary junction.
abstract: BACKGROUND
  The aim of this study was to establish an optimal management strategy for pancreatic disorders associated with anomalous pancreaticobiliary junction (APBJ).
  
  
  METHODS
  In 64 adult surgical cases of APBJ (common channel 15 mm or longer) (43 with and 21 without choledochal cyst), associated pancreatic disorders, pancreatographic results, and treatment outcomes were analyzed.
  
  
  RESULTS
  Of 64 patients, 56 had pancreatobiliary symptoms. Twenty-four patients (38%) had pancreatic disorders: acute pancreatitis (n = 20), chronic calcifying pancreatitis (n = 2), and pancreatic carcinoma (n = 2). Twenty patients (31%) had abnormal pancreatograms. The incidence of acute pancreatitis was significantly higher in patients with an abnormal pancreatogram, particularly dilatation, protein plugs or stones of the common channel or main pancreatic duct, and coexisting pancreatic ductal anomaly. All patients with choledochal cyst underwent cyst excision and hepaticojejunostomy. Eleven patients without choledochal cyst or pancreatobiliary carcinoma underwent cholecystectomy alone. Protein plugs and pancreatic stones were extracted through the bile duct stump or by sphincterotomy. No patients experienced pancreatitis during a mean postoperative follow-up of 6.7 years.
  
  
  CONCLUSIONS
  In managing APBJ, attention should be paid to the possibility of associated pancreatic disorders and an abnormal pancreatogram. APBJ with choledochal cyst requires cyst excision. Cholecystectomy alone may be adequate for APBJ without cyst.
authors.affiliation: First Department of Surgery, Kyorin University School of Medicine, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Sugiyama
authors.forename: Y
authors.initials: Y
authors.lastname: Atomi
authors.forename: A
authors.initials: A
authors.lastname: Kuroda
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001652:Bile Ducts / Q000002:abnormalities*; D002758:Cholangiography; D002763:Cholecystectomy; D015529:Choledochal Cyst / Q000150:complications / Q000601:surgery; D005260:Female; D006801:Humans; D007582:Jejunostomy; D008297:Male; D008875:Middle Aged; D010182:Pancreatic Diseases / Q000150:complications* / Q000601:surgery*; D010183:Pancreatic Ducts / Q000002:abnormalities* / Q000000981:diagnostic imaging; D010190:Pancreatic Neoplasms / Q000150:complications / Q000601:surgery; D010195:Pancreatitis / Q000150:complications / Q000601:surgery; D016896:Treatment Outcome