title: Influence of exercise training on physiological and performance changes with weight loss in men.
abstract: OBJECTIVE
  The purpose of this study was to examine the physiological effects of a weight-loss dietary regimen with or without exercise.
  
  
  METHODS
  Thirty-five overweight men were matched and randomly placed into either a control group (C; N = 6) or one of three dietary groups; a diet-only group (D; N = 8), a diet group that performed aerobic exercise three times per week (DE; N = 11); and a diet group that performed both aerobic and strength training three times per week (DES; N = 10).
  
  
  RESULTS
  After 12 wk, D, DE, and DES demonstrated a similar and significant (P < or = 0.05) reduction in body mass (-9.64, -8.99, and -9.90 kg, respectively) with fat mass comprising 69, 78, and 97% of the total loss in body mass, respectively. The diet-only group also demonstrated a significant reduction in fat-free mass. Maximum strength, as determined by 1-RM testing in the bench press and squat exercise was significantly increased for DES in both the bench press (+19.6%) and squat exercise (+32.6%). Absolute peak O2 consumption was significantly elevated in DE (+24.8%) and DES (+15.4%). There were no differences in performance during a 30-s Wingate test for the DE and DES, whereas D demonstrated a significant decline in peak and mean power output. Resting metabolic rate (RMR) (kcal x d(-1)) was not significantly different for any of the groups except for the DE group. There were no significant changes in basal concentrations of serum glucose, BUN, cortisol, testosterone, and high density lipoprotein (HDL) cholesterol for any of the groups. Serum total cholesterol and low density lipoprotein (LDL) cholesterol were significantly decreased for all dietary groups. Serum triglycerides were significantly reduced for D and DES at week 6 and remained lower at week 12 for D, while triglycerides returned to baseline values for DES.
  
  
  CONCLUSIONS
  These data indicate that a weight-loss dietary regimen in conjunction with aerobic and resistance exercise prevents the normal decline in fat-free mass and muscular power and augments body composition, maximal strength, and maximum oxygen consumption compared with weight-loss induced by diet alone.
authors.affiliation: Department of Kinesiology, Noll Physiological Research Center, The Pennsylvania State University, University Park 16802, USA. wkraemer@bsu.edu
authors.forename: W J
authors.initials: WJ
authors.lastname: Kraemer
authors.forename: J S
authors.initials: JS
authors.lastname: Volek
authors.forename: K L
authors.initials: KL
authors.lastname: Clark
authors.forename: S E
authors.initials: SE
authors.lastname: Gordon
authors.forename: S M
authors.initials: SM
authors.lastname: Puhl
authors.forename: L P
authors.initials: LP
authors.lastname: Koziris
authors.forename: J M
authors.initials: JM
authors.lastname: McBride
authors.forename: N T
authors.initials: NT
authors.lastname: Triplett-McBride
authors.forename: M
authors.initials: M
authors.lastname: Putukian
authors.forename: R U
authors.initials: RU
authors.lastname: Newton
authors.forename: K
authors.initials: K
authors.lastname: Häkkinen
authors.forename: J A
authors.initials: JA
authors.lastname: Bush
authors.forename: W J
authors.initials: WJ
authors.lastname: Sebastianelli
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001823:Body Composition; D015992:Body Mass Index; D004038:Diet, Reducing; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D009765:Obesity / Q000378:metabolism / Q000628:therapy*; D010101:Oxygen Consumption / Q000502:physiology*; D012044:Regression Analysis; D015431:Weight Loss / Q000502:physiology*
chemical_list: D008055:Lipids