Importance of levonorgestrel dose in oral contraceptives for effects on coagulation.
Combined oral contraceptives show clear differences in effect on the tissue factor-initiated coagulation test of activated protein C resistance, which is dependent on the presence and dosage of levonorgestrel. Multiphasic levonorgestrol oral contraceptives differ from monophasic contraceptives and resemble third-generation contraceptives.
Kluft
C
C
de Maat
M P
MP
Heinemann
L A
LA
Spannagl
M
M
Schramm
W
W
D020016:Activated Protein C Resistance; D001777:Blood Coagulation / Q000187:drug effects; D003277:Contraceptives, Oral, Combined / Q000494:pharmacology*; D003280:Contraceptives, Oral, Synthetic / Q000494:pharmacology; D005260:Female; D006801:Humans; D016912:Levonorgestrel / Q000008:administration & dosage* / Q000494:pharmacology
D003277:Contraceptives, Oral, Combined; D003280:Contraceptives, Oral, Synthetic; D016912:Levonorgestrel