title: [Description of palpebral involvement in Fraser's syndrome].
abstract: OBJECTIVE
  Fraser's syndrome is a rare multiple malformation involving the eyes, with cryptophthalmos. In its complete form, cryptophthalmos is a serious malformation with absence of eyelids and palpebral fissure. A review of ophthalmological signs is presented.
  
  
  METHODS
  A case of Fraser's syndrome is presented. Ophthalmological and somatic examination as well as evolution are described.
  
  
  RESULTS
  Incomplete cryptophthalmos with symblepharon and bilateral palpebral coloboma are present. Surgical treatment with palpebral reconstruction allowed preservation of visual acuity in one eye.
  
  
  CONCLUSIONS
  Ophthalmological signs are present in 93% of cases. Eyelid involvement such as symblepharon, and partial or complete coloboma are relatively frequent, whereas cryptophthalmos in its complete form are much more rare.
  
  
  CONCLUSIONS
  Treatment involves palpebral reconstructive surgery in order to preserve visual function.
authors.affiliation: Service d'Ophtalmologie, Hôpital Nord, Chemin des Bourrelys, Marseille.
authors.forename: E
authors.initials: E
authors.lastname: Hadjadj
authors.forename: J
authors.initials: J
authors.lastname: Conrath
authors.forename: D
authors.initials: D
authors.lastname: Denis
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis; D003103:Coloboma / Q000175:diagnosis; D005124:Eye Abnormalities / Q000175:diagnosis / Q000601:surgery; D005143:Eyelids / Q000002:abnormalities* / Q000601:surgery; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011379:Prognosis; D013577:Syndrome; D014792:Visual Acuity