Immunopathogenesis of multiple sclerosis: the role of T cells.
Multiple sclerosis is considered to be an autoimmune disease that results from aberrant immune responses to central nervous system antigens. T cells are considered to be crucial in orchestrating an immunopathological cascade that culminates in damage to the myelin sheath, oligodendrocytes and axons.
Martino
G
G
Department of Neurology, San Raffaele Scientific Insitute-DIBIT, Milan, Italy.
Hartung
H P
HP
D006801:Humans; D009103:Multiple Sclerosis / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*