title: [Neurosarcoma of the submandibular gland arising in a pleomorphic adenoma. Apropos of a case].
abstract: A 71-year-old woman consulted for a tumor of the right submandibular gland that had been present for 4 years and had rapidly increased in size during the last two months. Histological examination of frozen sections and immunohistochemistry concluded to a poor differentiated sarcoma probably a neurosarcoma with residual pleomorphic adenoma component. In spite of wide resection, local recurrences with nodes and lung metastases occurred leading to the death of the patient. We think interesting to report this unusual salivary tumor and to discuss its pathological features.
authors.affiliation: Service de Stomatologie et Chirurgie Maxillo-faciale, CHU Sahloul, Sousse, Tunisie.
authors.forename: H
authors.initials: H
authors.lastname: Khochtali
authors.forename: S
authors.initials: S
authors.lastname: Aoune
authors.forename: M
authors.initials: M
authors.lastname: Mokni
authors.forename: A
authors.initials: A
authors.lastname: Turki
authors.forename: D
authors.initials: D
authors.lastname: Abassi
authors.forename: A
authors.initials: A
authors.lastname: Bakir
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology*; D000368:Aged; D017809:Fatal Outcome; D005260:Female; D005629:Frozen Sections; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000556:secondary; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D018319:Neurofibrosarcoma / Q000473:pathology* / Q000556:secondary; D013365:Submandibular Gland Neoplasms / Q000473:pathology*