title: Myelofibrosis: an unusual presentation of vitamin D-deficient rickets.
abstract: We present the case of a breast-fed 5-month-old infant who presented with pancytopenia, secondary to intense myelofibrosis during the winter months because of undiagnosed rickets. The patient responded to oral vitamin D with rapid resolution of symptoms. Secondary hyperparathyroidism was the probable cause of the myelofibrosis.
  
  
  CONCLUSIONS
  Although nutritional rickets remains a problem in developing countries, children in northern climates in industrialized countries may also be at risk. Rickets must be considered when assessing myelofibrosis in a very young child.
authors.affiliation: Paediatric Haematology and Oncology Unit, Hôpital Nord, Saint Etienne, F-42055, Cx02, France. jlstephan@infonie.fr
authors.forename: J L
authors.initials: JL
authors.lastname: Stéphan
authors.forename: C
authors.initials: C
authors.lastname: Galambrun
authors.forename: A
authors.initials: A
authors.lastname: Dutour
authors.forename: F
authors.initials: F
authors.lastname: Freycon
mesh_terms: D006801:Humans; D007223:Infant; D008297:Male; D055728:Primary Myelofibrosis / Q000209:etiology*; D012279:Rickets / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D012307:Risk Factors; D014808:Vitamin D Deficiency / Q000150:complications*