title: Regulatory T cells and inflammatory bowel disease.
abstract: Recent studies have identified interleukin 10 as a differentiation factor for a novel subset of immune suppressive regulatory T cells. Here, Hervé Groux and Fiona Powrie discuss the role that these cells play in the regulation of immune responses to enteric antigens and suggest that a deficiency in these cells might be involved in the pathogenesis of inflammatory bowel disease.
authors.affiliation: INSERM U343, Hôpital de l'Archet, Route de Saint Antoine de Ginestières, 06200 Nice, France. groux@unice.fr
authors.forename: H
authors.initials: H
authors.lastname: Groux
authors.forename: F
authors.initials: F
authors.lastname: Powrie
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000276:immunology* / Q000473:pathology / Q000628:therapy; D016753:Interleukin-10 / Q000276:immunology; D051379:Mice; D016176:T-Lymphocyte Subsets / Q000276:immunology* / Q000473:pathology
chemical_list: D016753:Interleukin-10