Sorted averaging--principle and application to auditory brainstem responses.
A new averaging method for evoked potentials, called sorted averaging, is presented. The method requires an ensemble of sweeps stored in memory and is based on the principle of interchangeability of individual sweeps within this ensemble. Sorted averaging is applied by sorting all sweeps according to their estimated background noise and successive averaging of this sorted ensemble, starting with low-noise sweeps. Signal-to-noise power ratio (SNR2) is estimated by calculating the inverse single point variance (Elberling & Don, 1984). This SNR2 estimate increases linearly with the number of sweeps for standard averaging and shows a clear maximum for sorted averaging. Auditory brainstem responses to click stimuli at 70 dB nHL in 20 normal hearing subjects were recorded and 4000 individual sweeps during each run were stored for analysis. In an off-line analysis, SNR2 for standard averaging with 10 microV artefact rejection, for weighted averaging and for sorted averaging were calculated. Sorted averaging was found to yield a significantly higher SNR2.
Mühler
R
R
Department of Experimental Audiology and Medical Physics, Otto-von-Guericke-University Magdeburg, Germany. roland.muchler@medizin.uni-magdeburg.de
von Specht
H
H
D000161:Acoustic Stimulation / Q000379:methods*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D006309:Hearing / Q000502:physiology; D006801:Humans; D009622:Noise