Transcriptional regulation in Xenopus: a bright and froggy future.
Xenopus has played a key role in defining the general mechanisms that underlie early vertebrate development. Recent studies reveal how the transcriptional regulation of signaling and transcription factors is used to pattern the early dorsal-ventral axis. With the development of new methods for producing transgenic frogs, Xenopus will become a very attractive system for studying transcriptional regulation at all stages of embryogenesis.
Kimelman
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Department of Biochemistry Center for Developmental Biology University of Washington Seattle, Washington 98195-7350, USA. kimelman@u.washington.edu.
D000818:Animals; D047108:Embryonic Development; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000235:genetics; D014157:Transcription Factors / Q000378:metabolism; D014158:Transcription, Genetic; D014981:Xenopus / Q000235:genetics; D029867:Xenopus Proteins
D018398:Homeodomain Proteins; C093133:SIA1 protein, Xenopus; D014157:Transcription Factors; D029867:Xenopus Proteins