Predicting movement during anaesthesia by complexity analysis of electroencephalograms.
A new approach to predicting movement during anaesthesia by using complexity analysis of electroencephalograms (EEG) signals is presented. The raw EEG signal is first decomposed into six consecutive different scaling components by wavelet transform on the basis of its self-similarity. The Lempel-Ziv complexity measures C(n) are extracted from the raw EEG and its corresponding components by complexity analysis. Prediction of movement during anaesthesia is then made by a four-layer artificial neural network (ANN) using the C(n)s. The combination of these three different approaches enables the system to address the non-analytical, non-stationary, non-linear and dynamical properties of the EEG. From 20 dog experiments, 109 distinct EEG recordings are collected under isoflurane anaesthesia. Testing the ANN using the 'drop one dog' method, the performance obtained for the system in detecting movement is: sensitivity 88%, specificity 97% and accuracy 92%. Comparisons with other methods, such as spectral edge frequency, median frequency and principal component analysis, show that the proposed system has a certain advantage. This new method is computationally fast and well suited for realtime clinical implementation.
Zhang
X S
XS
Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Roy
R J
RJ
D000758:Anesthesia; D000818:Animals; D004285:Dogs; D004569:Electroencephalography; D009068:Movement; D016571:Neural Networks, Computer; D012815:Signal Processing, Computer-Assisted