title: Diagnostic approach to adults with hypoglycemic disorders.
abstract: Optimal conditions for confirming the presence and accurately diagnosing the type of hypoglycemic disorder occur at the time of a spontaneous spell. Otherwise, dynamic testing to generate conducive conditions should be conducted in any patient with a history of neuroglycopenic symptoms, regardless of relation to meal ingestion. Specific criteria regarding beta-cell polypeptide concentrations are required to establish hyperinsulinemia. Sulfonylureas in plasma should be measured with sensitive assays. In complex cases, the selective arterial calcium test may be a useful dynamic test.
authors.affiliation: Mayo Medical School, Rochester, Minnesota, USA.
authors.forename: F J
authors.initials: FJ
authors.lastname: Service
mesh_terms: D000906:Antibodies / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D002096:C-Peptide / Q000378:metabolism; D003937:Diagnosis, Differential; D005215:Fasting; D005951:Glucose Tolerance Test / Q000379:methods; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000209:etiology*; D007328:Insulin / Q000276:immunology
chemical_list: D000906:Antibodies; D001786:Blood Glucose; D002096:C-Peptide; D007328:Insulin