Digoxin and mortality in chronic heart failure. UK Heart Investigation.
Data from recent clinical trials suggest digoxin is now widely used in patients with chronic heart failure in sinus rhythm. We present data from a heart failure registry that reiterates concerns about the safety of digoxin in this population.
Lindsay
S J
SJ
Kearney
M T
MT
Prescott
R J
RJ
Fox
K A
KA
Nolan
J
J
D002316:Cardiotonic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004077:Digoxin / Q000009:adverse effects* / Q000627:therapeutic use; D006333:Heart Failure / Q000188:drug therapy* / Q000401:mortality*; D006801:Humans; D016016:Proportional Hazards Models; D011446:Prospective Studies; D012042:Registries / Q000706:statistics & numerical data; D012189:Retrospective Studies
D002316:Cardiotonic Agents; D004077:Digoxin