title: c-Irx2 expression reveals an early subdivision of the neural plate in the chick embryo.
abstract: We have cloned c-Irx2, a chick homologue of the Xiro2 and mIrx2 genes and a new member of the Iroquois family of homeodomain-containing transcription factors. Strikingly, c-Irx2 expression reveals an early subdivision of the neural plate at late primitive streak stages which later transiently resolves to a single stripe within the developing hindbrain corresponding to rhombomere 1.
authors.affiliation: Department of Human Anatomy and Genetics, University of Oxford, South Parks Rd., Oxford, UK.
authors.forename: A
authors.initials: A
authors.lastname: Goriely
authors.forename: R
authors.initials: R
authors.lastname: Diez del Corral
authors.forename: K G
authors.initials: KG
authors.lastname: Storey
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002531:Cerebellum / Q000196:embryology / Q000378:metabolism; D002642:Chick Embryo; D018076:DNA, Complementary / Q000378:metabolism; D015870:Gene Expression; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism*; D008636:Mesencephalon / Q000196:embryology / Q000378:metabolism*; D008969:Molecular Sequence Data; D012249:Rhombencephalon / Q000196:embryology / Q000378:metabolism*; D017386:Sequence Homology, Amino Acid; D013997:Time Factors; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D018076:DNA, Complementary; D018398:Homeodomain Proteins; D014157:Transcription Factors