title: What is the role of ultrasonography in the follow-up of adrenal incidentalomas? The Gruppo Piemontese Incidentalomi Surrenalici.
abstract: OBJECTIVE
  The incidental discovery of an adrenal mass has become a frequent finding because of the increased use and technical improvement of computed tomography (CT) and magnetic resonance imaging. The approach to the investigation of these masses is ill-defined, and unequivocal guidelines for their management are lacking. The first problem concerns the distinction between malignant masses requiring surgery and the more frequent benign masses. In the case of a benign mass, an additional problem is the method of follow-up, considering cost, discomfort to the patient, and the consequences of false-positive results. The aim of this study was to evaluate the possible role of ultrasonography (US) in the follow-up of incidentally discovered adrenal masses.
  
  
  METHODS
  Two hundred eight cases of adrenal incidentalomas consecutively diagnosed in Piedmont, Italy from 1989 to 1996 and collected for a retrospective multicenter analysis were used. The US and CT characteristics of the adrenal masses were compared in patients who underwent surgery.
  
  
  RESULTS
  Most patients were 50 to 69 years of age; women were predominantly affected. CT was more reliable than US in detecting the malignant nature of an adrenal lesion. The mass diameter measured by US and CT was clearly correlated.
  
  
  CONCLUSIONS
  At diagnosis, US was not sufficiently reliable in evaluating adrenal mass characteristics. Considering the high correlation between US and CT size estimation, in the case of a presumably benign lesion, US could be considered a simple, economic, and effective method of follow-up, with CT limited to evaluating masses growing over time (CT remains mandatory at diagnosis).
authors.affiliation: Dipartimento di Scienze Cliniche e Biologiche, Università degli Studi di Torino, Azienda Ospedaliera San Luigi, Orbassano, Turin, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Fontana
authors.forename: F
authors.initials: F
authors.lastname: Porpiglia
authors.forename: P
authors.initials: P
authors.lastname: Destefanis
authors.forename: C
authors.initials: C
authors.lastname: Fiori
authors.forename: A
authors.initials: A
authors.lastname: Alì
authors.forename: M
authors.initials: M
authors.lastname: Terzolo
authors.forename: G
authors.initials: G
authors.lastname: Osella
authors.forename: A
authors.initials: A
authors.lastname: Angeli
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging*; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014463:Ultrasonography