Malignant triton tumor of the head and neck: A case report and review of the literature.
BACKGROUND
Malignant triton tumor (MTT) is a relatively rare, aggressive tumor comprised of both malignant schwannoma cells and malignant rhabdomyoblasts. Because MTT frequently arises in the head and neck, the otolaryngologist must be aware of the nature of the tumor and its response to various treatment modalities.


METHODS
This article reviews the treatment and outcome of all reported cases of MTT arising in the head and neck.


CONCLUSIONS
Although statistical analysis is limited by the short duration of follow-up of many patients, complete tumor resection appears to carry an improved chance of survival. Adjuvant radiation and chemotherapy may also improve survival, although a benefit of these therapies was not well demonstrated in this small series.
Victoria
L
L
Department of Otolaryngology-Head and Neck Surgery, University of Iowa College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA.
McCulloch
T M
TM
Callaghan
E J
EJ
Bauman
N M
NM
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001707:Biopsy, Needle; D002648:Child; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D017809:Fatal Outcome; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008175:Lung Neoplasms / Q000556:secondary; D008279:Magnetic Resonance Imaging; D015080:Mesna / Q000008:administration & dosage; D009364:Neoplasm Recurrence, Local; D009442:Neurilemmoma / Q000175:diagnosis / Q000473:pathology / Q000556:secondary / Q000628:therapy*; D011879:Radiotherapy Dosage; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D005047:Etoposide; D003520:Cyclophosphamide; D015080:Mesna; D002945:Cisplatin; D007069:Ifosfamide