Identification of thorotrast by gamma-spectrometry and simplified autoradiography in pathological specimens.
Simplified and reliable methods for identifying thorotrast are demonstrated. On gamma-ray spectrometry, as little as 0.1 g of liver tissue gives gamma-ray spectrum characteristics to the thorium decay series, despite a low net count. When conventional film for photography is kept in contact with a paraffin section of the liver for 4 months, it develops silver grains exactly corresponding to the area of granular deposition. By combining this method with clinical and pathological findings, a diagnosis of thorotrastosis can be established without the need for special instruments or materials.
Yasumizu
R
R
First Department of Pathology, Kansai Medical Universtity, Osaka, Japan.
Amoh
Y
Y
Ikehara
S
S
D000368:Aged; D001345:Autoradiography; D003287:Contrast Media / Q000009:adverse effects / Q000378:metabolism*; D017809:Fatal Outcome; D006394:Hemangiosarcoma / Q000139:chemically induced / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000139:chemically induced / Q000378:metabolism* / Q000473:pathology; D008297:Male; D013051:Spectrometry, Gamma; D013911:Thorium Dioxide / Q000009:adverse effects / Q000378:metabolism*
D003287:Contrast Media; D013911:Thorium Dioxide