Differential nitric oxide synthase activity in ischemic and idiopathic dilated cardiomyopathy.
We measured plasma nitrite and interleukin 1beta levels in patients with idiopathic dilated cardiomyopathy, ischemic cardiomyopathy, and in normal controls. Nitrite levels were abnormally high in both ischemic and idiopathic dilated cardiomyopathy, suggesting increased nitric oxide activity in these conditions.
Rakhit
R D
RD
Department of Clinical Cardiology, Imperial College School of Medicine at Hammersmith Hospital, London, United Kingdom.
Tousoulis
D
D
Lefroy
D C
DC
Davies
G J
GJ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000503:physiopathology*; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000175:diagnosis / Q000503:physiopathology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007375:Interleukin-1 / Q000097:blood; D008297:Male; D008875:Middle Aged; D019001:Nitric Oxide Synthase / Q000502:physiology*; D009573:Nitrites / Q000097:blood; D011183:Postoperative Complications / Q000175:diagnosis / Q000503:physiopathology
D007375:Interleukin-1; D009573:Nitrites; D019001:Nitric Oxide Synthase