Protein conformational stabilities can be determined from hydrogen exchange rates.
Huyghues-Despointes
B M
BM
Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, 2153 Sheridan Road, Evanston, Illinois 60208, USA.
Scholtz
J M
JM
Pace
C N
CN
D003903:Deuterium / Q000378:metabolism; D017666:Deuterium Oxide / Q000378:metabolism; D006859:Hydrogen / Q000378:metabolism*; D007536:Isomerism; D007700:Kinetics; D011392:Proline / Q000378:metabolism; D011487:Protein Conformation; D011489:Protein Denaturation; D017510:Protein Folding; D006163:Ribonuclease T1 / Q000737:chemistry* / Q000378:metabolism*; D013696:Temperature; D013816:Thermodynamics
D006859:Hydrogen; D011392:Proline; D003903:Deuterium; D006163:Ribonuclease T1; D017666:Deuterium Oxide