Comparison of growth during continuous ambulatory peritoneal dialysis and renal transplantation using conventional immunosuppressive drugs in children.
OBJECTIVE
Growth during continuous ambulatory peritoneal dialysis (CAPD) and after renal transplantation (Tx) was assessed in children under the age of 12 years.


METHODS
Growth was assessed by calculating the standard deviation score for height of normal children of the same age and gender.


METHODS
Twenty-one patients undergoing CAPD and 13 patients who had received renal Tx at Kitasato University Hospital.


RESULTS
Overall growth in those children undergoing CAPD and after renal Tx was not good, but growth during CAPD seemed to be slightly better than after renal Tx using conventional immunosuppressive drugs. Only young children who had started CAPD or received renal Tx before the age of 5 years with functioning graft showed catch-up growth, but the final height of these children may still be smaller than normal.


CONCLUSIONS
Growth in children with end-stage renal disease is poor but growth during CAPD seems to be slightly better than after renal Tx using conventional immunosuppressive drugs.
Iitaka
K
K
Department of Pediatrics, Yamato City Hospital, Kanagawa, Japan.
Hojo
M
M
Moriya
S
S
Sakai
T
T
Endo
T
T
D000367:Age Factors; D001379:Azathioprine / Q000627:therapeutic use; D001827:Body Height; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000097:blood; D003520:Cyclophosphamide / Q000627:therapeutic use; D004921:Erythropoietin / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006085:Graft Survival; D006128:Growth / Q000502:physiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007223:Infant; D007676:Kidney Failure, Chronic / Q000503:physiopathology / Q000601:surgery / Q000628:therapy; D016030:Kidney Transplantation / Q000502:physiology; D008297:Male; D010531:Peritoneal Dialysis, Continuous Ambulatory; D011239:Prednisolone / Q000627:therapeutic use
D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D004921:Erythropoietin; D003520:Cyclophosphamide; D011239:Prednisolone; D003404:Creatinine; D001379:Azathioprine