[Urgent protection of cells from foot-and-mouth infection by blocking their receptors with antigen molecules].
Molecules of foot-and-mouth disease (FMD) virus interacting with susceptible porcine kidney cells block their receptors and inhibit FMD virus infection. Adsorption of inactivated virus by cells is rapid, reversible, and type-specific. Efficacy of cell receptor blocking and protection from FMD depends on the dose of specific antigen and adequate saturation.
Dudnikov
A I
AI
Cherniaev
Iu A
IuA
Gnevashev
V M
VM
Mikhalishin
V V
VV
Pruntova
O V
OV
D000818:Animals; D000956:Antigens, Viral / Q000276:immunology*; D005537:Aphthovirus / Q000276:immunology*; D002460:Cell Line; D005536:Foot-and-Mouth Disease / Q000276:immunology / Q000517:prevention & control*; D011956:Receptors, Cell Surface / Q000037:antagonists & inhibitors* / Q000276:immunology; D013552:Swine
D000956:Antigens, Viral; D011956:Receptors, Cell Surface