title: Acute cholestatic hepatitis by cytomegalovirus in an immunocompetent patient resolved with ganciclovir.
abstract: We report a case of acute cholestatic hepatitis in an immunocompetent young male with cytomegalovirus (CMV) primoinfection episode. The severity of the clinical symptoms led to a high-dose treatment with parenteral ganciclovir, with an immediate response and total resolution of symptoms. Therapeutic options are discussed, particularly the use of ganciclovir, even in immunocompetent patients when the severity of the symptoms could demand it.
authors.affiliation: Department of Gastroenterology, Ramón y Cajal Hospital, Faculty of Medicine, Alcalá de Henares University, Madrid, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Serna-Higuera
authors.forename: M
authors.initials: M
authors.lastname: González-García
authors.forename: J M
authors.initials: JM
authors.lastname: Milicua
authors.forename: V
authors.initials: V
authors.lastname: Muñoz
mesh_terms: D000208:Acute Disease; D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage*; D002780:Cholestasis, Intrahepatic / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D018572:Disease-Free Survival; D015774:Ganciclovir / Q000008:administration & dosage*; D006525:Hepatitis, Viral, Human / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007121:Immunocompetence; D008297:Male; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D015774:Ganciclovir