Construction of sequence-selective peptide receptors from conformationally restricted eta- and theta- amino acids.
Oligomeric chemoreceptors for tripeptides have been constructed from a set of novel eta- and theta-amino acids. Screening against an encoded combinatorial tripeptide library has revealed two new small molecule chemoreceptor motifs with highly sequence-selective binding properties.
Ryan
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Department of Chemistry, Columbia University, New York, NY 10027, USA.
Still
W C
WC
D000596:Amino Acids / Q000737:chemistry*; D015394:Molecular Structure; D009842:Oligopeptides / Q000378:metabolism; D018000:Receptors, Peptide / Q000737:chemistry* / Q000378:metabolism
D000596:Amino Acids; D009842:Oligopeptides; D018000:Receptors, Peptide