Anthropomorphic carotid bifurcation phantom for MRI applications.
Anthropomorphic carotid bifurcation flow phantoms that incorporate different stenotic geometries within the internal carotid artery have been developed. This technique produces high-fidelity, life-size vascular flow models that are compatible with magnetic resonance techniques. The models, in conjunction with a computer-controlled flow pump, address the need for a complex vascular geometry that can be used to verify magnetic resonance angiography (MRA) techniques that quantify stenosis severity and blood flow. Stenotic geometries, with up to 80% diameter reduction, have been fabricated in two different phantom materials. Plastic phantoms provide a durable, rigid geometry where the absolute dimensions of the model are well known. Agar gel phantoms provide tissue-like signal (T1, T2) up to the lumen boundary and are also compatible with ultrasound techniques. In this paper the technique to produce vascular flow phantoms is outlined and the compatibility of these phantoms with MRA techniques is demonstrated. J. Magn. Reson. Imaging 1999;10:533-544.
Smith
R F
RF
Imaging Research Laboratories, The John P. Robarts Research Institute, London, Ontario, Canada.
Rutt
B K
BK
Holdsworth
D W
DW
D002339:Carotid Arteries / Q000033:anatomy & histology* / Q000502:physiology; D016893:Carotid Stenosis / Q000175:diagnosis; D006801:Humans; D018810:Magnetic Resonance Angiography; D019047:Phantoms, Imaging; D012039:Regional Blood Flow