Microtubule cytoskeleton: No longer an also Ran.
The Ran GTPase cycle has been extensively studied in the context of nuclear transport. Recent work indicates that this GTPase cycle also plays an important role in regulating the microtubule cytoskeleton.
Desai
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Max-Planck-Institute of Molecular Cell Biology and Genetics Meyerhofstrasse 1, 69117, Heidelberg, Germany. desai@EMBL-Heidelberg. de
Hyman
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D000818:Animals; D018385:Centrosome / Q000502:physiology / Q000648:ultrastructure; D002843:Chromatin / Q000502:physiology; D006160:Guanosine Triphosphate / Q000502:physiology; D006801:Humans; D008870:Microtubules / Q000502:physiology* / Q000648:ultrastructure; D008954:Models, Biological; D009024:Morphogenesis; D005810:Multigene Family; D009865:Oocytes; D008941:Spindle Apparatus / Q000502:physiology / Q000648:ultrastructure; D014982:Xenopus laevis; D020931:ran GTP-Binding Protein / Q000235:genetics / Q000502:physiology*
D002843:Chromatin; D006160:Guanosine Triphosphate; D020931:ran GTP-Binding Protein