Relation between interstitial myocardial collagen and the degree of clinical impairment in Chagas' disease.
Cardiac performance is negatively associated with interstitial collagen in Chagas' cardiomyopathy. The magnitude of dysfunction is related to the degree of collagen, and this association seems to exhibit a threshold above it if definite cardiac deterioration occurs.
Mady
C
C
Heart Institute and Department of Pathology, University of São Paulo Medical School, Brazil. carvdebora@incor.usp.br
Ianni
B M
BM
Arteaga
E
E
Montes
G S
GS
Caldini
E G
EG
Andrade
G
G
Giorgi
M C
MC
Saldiva
P H
PH
D000328:Adult; D014355:Chagas Disease / Q000473:pathology* / Q000503:physiopathology*; D003094:Collagen; D005260:Female; D005355:Fibrosis / Q000175:diagnosis; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D015635:Radionuclide Ventriculography
D003094:Collagen