Red cell enzyme polymorphisms in Moroccans and southern Spaniards: new data for the genetic history of the western Mediterranean.
Population samples from Morocco (El Jadida, south Atlantic coast) and La Alpujarra (Granada mountains, Spain), located on both shores of the western Mediterranean, were typed for 8 erythrocyte genetic markers: ACP1, ESD, PGD, AK1, GLO1, PGM1, SODA, and DIA. Genetic heterogeneity within western Mediterranean groups was investigated on the basis of allele frequencies of these 8 polymorphisms plus ABO and Rh (CDE). Only slight peculiarities for the ACP1, GLO1, and AK1 systems were observed in the 2 samples compared with other Mediterranean data. The new data are consistent with a main north to south genetic differentiation in the Mediterranean region. However, with regard to other European groups, the La Alpujarra population shows a particular affinity with North Africans that may be compatible with both an ancient common substratum and/or a special historical influence during the Muslim domination of the Iberian Peninsula.
Kandil
M
M
Département de Biologie, Faculté des Sciences, Université Chouaïb Doukkali, El Jadida, Morocco.
Moral
P
P
Esteban
E
E
Autori
L
L
Mameli
G E
GE
Zaoui
D
D
Calo
C
C
Luna
F
F
Vacca
L
L
Vona
G
G
D000328:Adult; D000483:Alleles; D004798:Enzymes / Q000235:genetics*; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D014644:Genetic Variation; D006801:Humans; D008297:Male; D019083:Mediterranean Region; D009018:Morocco; D010641:Phenotype; D011110:Polymorphism, Genetic; D012494:Sampling Studies; D013030:Spain
D004798:Enzymes; D005819:Genetic Markers