Parallel synthesis with fluorous reagents and reactants.
Fluorous reagents and reactants provide emerging new options in parallel synthesis because they are easily prepared, reacted, and then separated from the desired reaction products. Some background information on fluorous reaction and separation techniques is provided, and the utility of fluorous reagents and reactants is illustrated with a number of case studies that feature both liquid-liquid and solid-solid separations.
Curran
D P
DP
Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA.
D000478:Alkylation; D055598:Chemical Phenomena; D002626:Chemistry, Pharmaceutical; D002627:Chemistry, Physical; D017611:Fluorine Compounds / Q000737:chemistry*; D006801:Humans; D007202:Indicators and Reagents / Q000737:chemistry*; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry
D017611:Fluorine Compounds; D007202:Indicators and Reagents; D009930:Organic Chemicals