title: [Thiomersal in gammaglobulin for pregnant travellers may not be safe for the fetus. National Coordination Center for Travel Advisory].
abstract: It is not advisible to use thiomersal-containing gammaglobulin preparations for the prevention of hepatitis A in pregnant women. The current preparation of Sanquin-Centraal Laboratorium voor de Bloedtransfusiedienst will yield per 5 ml about 285 micrograms of ethylmercury. This exposure to ethylmercury may not be safe for the foetus and alternatives without ethylmercury are readily available.
authors.affiliation: Vaccinatiebureau, GG&GD, Amsterdam.
authors.forename: H J
authors.initials: HJ
authors.lastname: Schilthuis
authors.forename: J H
authors.initials: JH
authors.lastname: van Wijnen
mesh_terms: D000328:Adult; D002675:Child, Preschool; D000075202:Contraindications; D005260:Female; D006506:Hepatitis A / Q000517:prevention & control*; D006801:Humans; D007116:Immunization, Passive; D007142:Immunoglobulin gamma-Chains / Q000009:adverse effects*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects* / Q000378:metabolism; D013849:Thimerosal / Q000009:adverse effects* / Q000378:metabolism; D014195:Travel
chemical_list: D007142:Immunoglobulin gamma-Chains; D011310:Preservatives, Pharmaceutical; D013849:Thimerosal