title: Comparison of general and regional anesthesia for cesarean section: success rate, blood loss and satisfaction from a randomized trial.
abstract: OBJECTIVE
  A prospective randomized trial was organized to compare the effectiveness of general and regional anesthesia for cesarean section (C/S).
  
  
  METHODS
  Three hundred and forty-one patients were randomized into the general anesthesia group (GA), epidural anesthesia group (EA) and spinal anesthesia group (SA). The effectiveness of interest was success rate, blood loss and patient satisfaction.
  
  
  RESULTS
  We found that the success rates of EA and SA were lower than GA. Success in EA should be improved by using an epidural catheter to add more local anesthetic drug instead of a single shot; and the surgeon should allow more time for the block to work adequately. Success in SA should be improved by using bupivacaine instead of lidocaine. GA resulted in significantly more blood loss, lower postoperative hematocrit, and higher proportion of patients who had postoperative hematocrit < 30 per cent than EA and SA. The patients' satisfaction scores were not different among the 3 techniques. This meant that, given adequate explanation and perioperative care, Thai women were satisfied with regional anesthesia.
  
  
  CONCLUSIONS
  Regional anesthesia is a better choice of anesthesia for C/S than general anesthesia. However, the availability of different techniques and ability to change the technique when needed were very useful and important. If GA is chosen, all safety procedures must be followed. Oxygen supplement and endotracheal intubation facilities must be available in all techniques. Guidelines of anesthesia for C/S at a national level should be agreed upon, including the type of personnel, monitoring equipment and postoperative care.
authors.affiliation: Department of Anesthesiology, and Clinical Epidemiology Unit, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: J
authors.initials: J
authors.lastname: Lertakyamanee
authors.forename: T
authors.initials: T
authors.lastname: Chinachoti
authors.forename: T
authors.initials: T
authors.lastname: Tritrakarn
authors.forename: J
authors.initials: J
authors.lastname: Muangkasem
authors.forename: A
authors.initials: A
authors.lastname: Somboonnanonda
authors.forename: T
authors.initials: T
authors.lastname: Kolatat
mesh_terms: D000328:Adult; D000767:Anesthesia, Epidural / Q000379:methods; D000768:Anesthesia, General / Q000379:methods; D000773:Anesthesia, Obstetrical / Q000379:methods*; D000775:Anesthesia, Spinal / Q000379:methods; D016063:Blood Loss, Surgical / Q000503:physiopathology*; D001810:Blood Volume; D002585:Cesarean Section; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D010147:Pain Measurement; D017060:Patient Satisfaction; D011247:Pregnancy; D011446:Prospective Studies; D016896:Treatment Outcome