title: Energetics of substrate binding, catalysis, and product release.
authors.affiliation: Institute for Enzyme Research, University of Wisconsin, Madison 53705-4098, USA.
authors.forename: W W
authors.initials: WW
authors.lastname: Cleland
authors.forename: D B
authors.initials: DB
authors.lastname: Northrop
mesh_terms: D000591:Amino Acid Isomerases / Q000737:chemistry; D002256:Carbonic Anhydrases / Q000737:chemistry; D002384:Catalysis; D004798:Enzymes / Q000737:chemistry*; D006860:Hydrogen Bonding; D009964:Orotidine-5'-Phosphate Decarboxylase / Q000737:chemistry; D011485:Protein Binding; D012697:Serine Endopeptidases / Q000737:chemistry; D012984:Software; D055672:Static Electricity; D013379:Substrate Specificity; D013696:Temperature; D013816:Thermodynamics
chemical_list: D004798:Enzymes; D012697:Serine Endopeptidases; D009964:Orotidine-5'-Phosphate Decarboxylase; D002256:Carbonic Anhydrases; D000591:Amino Acid Isomerases; C022451:proline racemase