Low molecular weight heparin use during pregnancy: issues of safety and practicality.
Low molecular weight heparin is an important agent for the treatment and prophylaxis against venous thromboembolism during pregnancy. It offers several distinct advantages over unfractionated heparin. A systematic search was performed of the literature review of low molecular weight heparin use in pregnancy and presents a practical approach to its use by obstetricians and internists.


BACKGROUND
Obstetricians & Gynecologists, Family Physicians.


OBJECTIVE
After completion of this article, the reader will be able to understand the pharmacology and the elimination of low molecular weight heparin, the potential side effects and how to appropriately monitor the drug, and the indications and management of the low molecular weight heparins during pregnancy.
Chan
W S
WS
Department of Medicine, Women's College Hospital, University of Toronto, Ontario, Canada.
Ray
J G
JG
D001777:Blood Coagulation / Q000187:drug effects; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000517:prevention & control* / Q000628:therapy; D012449:Safety; D013923:Thromboembolism / Q000517:prevention & control*
D006495:Heparin, Low-Molecular-Weight