Novel antifungal drugs.
There have been many new developments in antifungal therapy in the past few years. Some antifungal drugs have been reformulated to reduce toxicity (e.g. new lipid formulations of polyenes), and new derivatives of drugs have been developed to enhance potencies. The search for unique drug targets will be enhanced by the availability of sequencing data from whole genome sequencing projects.
DiDomenico
B
B
Schering-Plough Research Institute K15/4700, 2015 Galloping Hill Road, Kenilworth, NJ 07033-1300, USA.
D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D002462:Cell Membrane / Q000187:drug effects; D002473:Cell Wall / Q000187:drug effects; D005656:Fungal Proteins / Q000096:biosynthesis / Q000378:metabolism; D005658:Fungi / Q000187:drug effects*; D006801:Humans; D009181:Mycoses / Q000188:drug therapy; D011500:Protein Synthesis Inhibitors / Q000737:chemistry / Q000494:pharmacology*
D000935:Antifungal Agents; D005656:Fungal Proteins; D011500:Protein Synthesis Inhibitors