title: [Juvenile angiofibroma of skull base: diagnosis and treatment].
abstract: 227 young men and boys aged 9-22 years underwent treatment for juvenile angiofibroma of the base of the skull (JAFBS) in the ENT clinic of the Russian Academy of the Advanced Medical Education between 1977 and 1998. JAFBS was most frequently diagnosed at the age 15-18 years. An original clinicotopographic JAFBS classification is proposed basing on the disease spread. A complex of tests has established that JAFBS patients develop changes in hormonal and immunological statuses. Indications to ligation of the external carotid arteries and a modified nasomaxillary approach to angiofibroma providing radical removal of the tumor are described. After surgical treatment only 11.5% of the patients exhibited recurrent tumors.
authors.forename: V S
authors.initials: VS
authors.lastname: Pogosov
authors.forename: N A
authors.initials: NA
authors.lastname: Miroshnichenko
mesh_terms: D000293:Adolescent; D000328:Adult; D018322:Angiofibroma / Q000175:diagnosis* / Q000601:surgery*; D002342:Carotid Artery, External / Q000601:surgery; D002648:Child; D006801:Humans; D008026:Ligation; D008297:Male; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D019292:Skull Base Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D013514:Surgical Procedures, Operative / Q000379:methods*; D016896:Treatment Outcome