title: Co-morbid psychiatric disorder in chronic epilepsy: recognition and etiology of depression.
abstract: This article briefly presents one approach to conceptualizing known and suspected risk factors for co-morbid psychiatric disorder in epilepsy. The utility of this model is then reviewed by examining selected neurobiologic, psychosocial, and iatrogenic risk factors for a common co-morbid psychiatric disorder, interictal depression. Finally, data are presented concerning the rates of current and lifetime mood disorders among a sample of 76 patients with chronic complex partial seizures, the degree to which co-morbid depression has been recognized and treated in chronic epilepsy, and the health-related quality of life status associated with current and past mood disorders. Finally, these findings are related to the larger literature concerned with the recognition and treatment of depression.
authors.affiliation: Department of Psychology, Chicago Medical School, IL, USA.
authors.forename: P
authors.initials: P
authors.lastname: Wiegartz
authors.forename: M
authors.initials: M
authors.lastname: Seidenberg
authors.forename: A
authors.initials: A
authors.lastname: Woodard
authors.forename: B
authors.initials: B
authors.lastname: Gidal
authors.forename: B
authors.initials: B
authors.lastname: Hermann
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003866:Depressive Disorder / Q000150:complications / Q000523:psychology*; D004827:Epilepsy / Q000150:complications / Q000523:psychology*; D006801:Humans