Photomodulation of the Conformation of Cyclic Peptides with Azobenzene Moieties in the Peptide Backbone.
The cisright harpoon over left harpoon trans photoisomerization of the azobenzene building block 4-(4-aminophenylazo)benzoic acid incorporated in a cyclic peptide (see scheme) facilitated a two-state transition of the peptide chain from a rigid constrained conformation in the trans isomer into the largely free conformational space of the cis isomer.
Behrendt
R
Max-Planck-Institut für Biochemie, Am Klopferspitz 18A, D-82152 Martinsried (Germany).
Renner
C
Schenk
M
Wang
F
Wachtveitl
J
Oesterhelt
D
Moroder
L