A case of group II non-specific interstitial pneumonia developed during corticosteroid therapy after acute respiratory distress syndrome.
Non-specific interstitial pneumonia/fibrosis (NSIP) is a relatively new entity among idiopathic interstitial pneumonias. This disease is pathologically characterized by varying proportions of interstitial inflammation and fibrosis that appear to occur over a single, short period of time, and is clinically characterized by a generally good prognosis. Although corticosteroid therapy is widely considered to be effective for treatment of this disease, we report a case of Group II NSIP which developed during treatment with corticosteroid 4 months after acute respiratory distress syndrome (ARDS). This case suggests that any group of NSIP may be developed after ARDS, and that low-dose corticosteroid treatment is not sufficient to prevent the development of NSIP.
Ishioka
S
S
Second Department of Internal Medicine, Hiroshima University School of Medicine, Japan.
Nishisaka
T
T
Maeda
A
A
Hiyama
K
K
Yamakido
M
M
D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008168:Lung / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000209:etiology* / Q000473:pathology; D008775:Methylprednisolone / Q000627:therapeutic use*; D008875:Middle Aged; D012128:Respiratory Distress Syndrome / Q000150:complications* / Q000188:drug therapy
D005938:Glucocorticoids; D008775:Methylprednisolone