[Review of ophthalmologic complications in hereditary bullous epidermolysis. Apropos of 40 cases].
BACKGROUND
We assessed the frequency of ophthalmologic signs in inherited epidermolysis bullosa and evaluated follow-up.


METHODS
Forty patients were studied retrospectively. Of the 40 patients, 38 had dystrophic and 2 had junctional epidermolysis bullosa. A complete ocular examination was performed in all cases and repeated if necessary (8 times).


RESULTS
Ocular complications were found in 75% of the patients. Corneal anomalies associated or not with refractive anomalies were present. The best corrected visual acuity was less than 3/10 in 20% of the cases. Only 15% had lid modifications.


CONCLUSIONS
In our series, 75% of the cases had ocular anomalies, similar to other series in the literature. Corneal problems dominated.


CONCLUSIONS
Ocular lesions in inherited epidermolysis bullosa are often found and require initial ocular examination. Corneal lesions also need to be followed with optical correction to optimize functional prognosis.
Deplus
S
S
Service d'Ophtalmologie, Hôpital Saint-Louis, Paris.
Bremond-Gignac
D
D
Blanchet-Bardon
C
C
Febrarro
J L
JL
Gaudric
A
A
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000002:abnormalities; D003320:Corneal Ulcer / Q000175:diagnosis / Q000209:etiology; D004820:Epidermolysis Bullosa / Q000150:complications*; D016108:Epidermolysis Bullosa Dystrophica / Q000150:complications; D016109:Epidermolysis Bullosa, Junctional / Q000150:complications; D005128:Eye Diseases / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D011379:Prognosis; D011625:Pterygium / Q000175:diagnosis / Q000209:etiology; D012030:Refractive Errors / Q000175:diagnosis / Q000209:etiology; D012189:Retrospective Studies; D013997:Time Factors; D014792:Visual Acuity