title: Crustacean hyperglycemic hormone in the lobster nervous system: localization and release from cells in the subesophageal ganglion and thoracic second roots.
abstract: Crustacean hyperglycemic hormones (CHHs) are neuropeptides involved in the regulation of hemolymph glucose. The primary source of CHHs has been identified as the neurosecretory neurons of the eyestalk X-organ and its associated neurohemal organ, the sinus gland. We have identified another source of CHH-like peptides in the nervous system. With the use of immunocytochemistry, cells in the second roots of the thoracic ganglia have been observed to stain positively for CHH-reactive material. We also identified a pair of cells in the subesophageal ganglion that contain large amounts of CHH-reactive material. Depolarization of these cells with elevated potassium mediates a calcium-dependent release of CHH-like material from the ganglion as quantified with an enzyme-linked immunosorbent assay (ELISA).
authors.affiliation: Bodega Marine Laboratory, University of California, Bodega Bay, California 94923, USA. eschang@ucdavis.edu
authors.forename: E S
authors.initials: ES
authors.lastname: Chang
authors.forename: S A
authors.initials: SA
authors.lastname: Chang
authors.forename: B S
authors.initials: BS
authors.lastname: Beltz
authors.forename: E A
authors.initials: EA
authors.lastname: Kravitz
mesh_terms: D000818:Animals; D004947:Esophagus / Q000294:innervation; D017952:Ganglia, Invertebrate / Q000166:cytology / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D006458:Hemolymph / Q000378:metabolism; D006943:Hyperglycemia / Q000378:metabolism*; D007150:Immunohistochemistry; D007447:Invertebrate Hormones / Q000378:metabolism*; D008121:Nephropidae / Q000378:metabolism*; D009479:Neuropeptides / Q000378:metabolism*; D009490:Neurosecretory Systems / Q000502:physiology; D013126:Spinal Nerve Roots / Q000378:metabolism; D013909:Thorax / Q000294:innervation
chemical_list: D007447:Invertebrate Hormones; D009479:Neuropeptides; D005947:Glucose