Postpartum cerebellar herniation in von Hippel-Lindau syndrome.
OBJECTIVE
To describe exacerbation during pregnancy of cerebellar hemangioblastoma in von Hippel-Lindau syndrome.


METHODS
Case-report. A 21-year-old woman with von Hippel-Lindau syndrome was found on routine ocular examination to have severe papilledema 1 week after giving birth.


RESULTS
Immediate magnetic resonance imaging disclosed a large cerebellar cyst from hemangioblastoma causing cerebellar tonsillar herniation. Immediate neurosurgical intervention was life saving.


CONCLUSIONS
Worsening of intracranial hemangioblastoma during pregnancy in cases of von Hippel-Lindau syndrome should be realized and periodic neurologic and ophthalmologic observation is warranted.
Othmane
I S
IS
Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Shields
C
C
Singh
A
A
Shields
J
J
Goldman
W
W
D000208:Acute Disease; D000328:Adult; D002526:Cerebellar Diseases / Q000175:diagnosis / Q000209:etiology; D002528:Cerebellar Neoplasms / Q000150:complications* / Q000175:diagnosis; D004677:Encephalocele / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D018325:Hemangioblastoma / Q000150:complications* / Q000175:diagnosis; D018324:Hemangioma, Capillary / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000209:etiology; D008279:Magnetic Resonance Imaging; D010211:Papilledema / Q000175:diagnosis / Q000209:etiology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis; D019572:Retinal Neoplasms / Q000150:complications* / Q000175:diagnosis; D013577:Syndrome; D006623:von Hippel-Lindau Disease / Q000150:complications* / Q000175:diagnosis