title: Depression, coronary events, platelet inhibition, and serotonin reuptake inhibitors.
abstract: There is substantial clinical evidence that the incidence of depression and mortality after acute coronary events are strongly related. As mediators of coronary thrombosis, platelets may represent a link between these events, and could be possibly targeted by therapy with serotonin reuptake inhibitors.
authors.forename: G V
authors.initials: GV
authors.lastname: Nair
authors.forename: P A
authors.initials: PA
authors.lastname: Gurbel
authors.forename: C M
authors.initials: CM
authors.lastname: O'Connor
authors.forename: W A
authors.initials: WA
authors.lastname: Gattis
authors.forename: S R
authors.initials: SR
authors.lastname: Murugesan
authors.forename: V L
authors.initials: VL
authors.lastname: Serebruany
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D002986:Clinical Trials as Topic; D003863:Depression / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D009203:Myocardial Infarction / Q000097:blood / Q000401:mortality / Q000523:psychology*; D012307:Risk Factors; D017367:Selective Serotonin Reuptake Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D020280:Sertraline / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000928:Antidepressive Agents; D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline