title: An overlapping subzone technique for MR-based elastic property reconstruction.
abstract: A finite element-based nonlinear inversion scheme for magnetic resonance (MR) elastography is detailed. The algorithm operates on small overlapping subzones of the total region of interest, processed in a hierarchical order as determined by progressive error minimization. This zoned approach allows for a high degree of spatial discretization, taking advantage of the data-rich environment afforded by the MR. The inversion technique is tested in simulation under high-noise conditions (15% random noise applied to the displacement data) with both complicated user-defined stiffness distributions and realistic tissue geometries obtained by thresholding MR image slices. In both cases the process has proved successful and has been capable of discerning small inclusions near 4 mm in diameter. Magn Reson Med 42:779-786, 1999.
authors.affiliation: Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire, USA. elijah.van.houten@dartmouth.edu
authors.forename: E E
authors.initials: EE
authors.lastname: Van Houten
authors.forename: K D
authors.initials: KD
authors.lastname: Paulsen
authors.forename: M I
authors.initials: MI
authors.lastname: Miga
authors.forename: F E
authors.initials: FE
authors.lastname: Kennedy
authors.forename: J B
authors.initials: JB
authors.lastname: Weaver
mesh_terms: D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology; D001940:Breast / Q000033:anatomy & histology; D004548:Elasticity; D005260:Female; D020342:Finite Element Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male