Auto--antibodies to DNA in the sera of Nigerians attending a rheumatic diseases clinic.
The presence of auto-antibodies to DNA in the sera of 199 Nigerians: 46 with osteoarthritis, 16 with rheumatoid arthritis, 5 with SLE, 18 with chronic hepatitis, 24 peptic ulcer disease and 90 blood donors were assayed using a haemagglutination method. The positivity rates of auto-antibodies to DNA in these subjects were comparable [X2 = 1.56, P > 0.10]. The results of this study shows that the presence of auto-antibodies to DNA is not a reliable diagnostic index for auto-immune phenomena.
Adelowo
O O
OO
Department of Medicine, Ogun State University Teaching Hospital, Sagamu, Nigeria.
Salimonu
L S
LS
Arinola
O G
OG
D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood*; D001172:Arthritis, Rheumatoid / Q000097:blood / Q000175:diagnosis / Q000276:immunology*; D001782:Blood Donors; D002908:Chronic Disease; D005260:Female; D006505:Hepatitis / Q000097:blood / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000175:diagnosis / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D010003:Osteoarthritis / Q000097:blood / Q000175:diagnosis / Q000276:immunology*; D010437:Peptic Ulcer / Q000097:blood / Q000175:diagnosis / Q000276:immunology*
D000974:Antibodies, Antinuclear