title: [HPV infection of the genital system: new findings].
abstract: The expansion of our knowledge in the field of pathology, epidemiology and molecular biology of human papillomaviruses (HPV) has defined them as the major and best understood class of human tumor viruses. The interaction of HPV with genome of host cells produces the majority of cytologic abnormalities responsible for neoplastic transformation and makes early cervical cancer screening possible. This review of the current knowledge of HPV infection biology, diagnosis and therapy facilitates understanding of the clinical significance of these viruses.
authors.affiliation: Zentrum für Gynäkologie im Krankenhaus Maingau vom Roten Kreuz, Frankfurt am Main, Deutschland.
authors.forename: Z
authors.initials: Z
authors.lastname: Hrgović
authors.forename: A
authors.initials: A
authors.lastname: Salihagić
authors.forename: M
authors.initials: M
authors.lastname: Kusan
mesh_terms: D002472:Cell Transformation, Viral; D005260:Female; D006801:Humans; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000628:therapy; D014412:Tumor Virus Infections / Q000175:diagnosis / Q000628:therapy; D002577:Uterine Cervical Diseases / Q000175:diagnosis / Q000628:therapy / Q000821:virology; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000628:therapy / Q000821:virology