title: Genetic variation of three tetrameric tandem repeats in four distinct Israeli ethnic groups.
abstract: The allele frequency distributions of three STR loci amplified by PCR have been studied in four Israeli communities: Ashkenazi Jews and three non-Ashkenazi groups, namely Moroccan, Yemenite, and Ethiopian Jews. The loci analyzed were CSF1PO, TPOX, and HUMTHO1. The typing was performed in sequencing polyacrylamide gels under denaturing conditions that could separate alleles with differences of a single base. The population data were analyzed with respect to Hardy-Weinberg (H-W) equilibrium and found that all loci meet the H-W expectations. No-ticeable differences were encountered between the four Jewish ethnic groups studied hereby indicating the importance of establishing a local database to be used in human identity testing in these different Israeli Jewish groups.
authors.affiliation: Tissue Typing Unit, Hadasah Medical Organization, Jerusalem, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Amar
authors.forename: C
authors.initials: C
authors.lastname: Brautbar
authors.forename: U
authors.initials: U
authors.lastname: Motro
authors.forename: T
authors.initials: T
authors.lastname: Fisher
authors.forename: B
authors.initials: B
authors.lastname: Bonne-Tamir
authors.forename: S
authors.initials: S
authors.lastname: Israel
mesh_terms: D004247:DNA / Q000737:chemistry; D016172:DNA Fingerprinting; D019281:Dimerization; D005002:Ethiopia / Q000208:ethnology; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D005819:Genetic Markers / Q000235:genetics; D014644:Genetic Variation; D006801:Humans; D007557:Israel / Q000453:epidemiology; D007585:Jews / Q000235:genetics; D018598:Minisatellite Repeats / Q000235:genetics*; D009018:Morocco / Q000208:ethnology; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*; D015006:Yemen / Q000208:ethnology
chemical_list: D005819:Genetic Markers; D004247:DNA