title: Adenosine-induced transient asystole for management of a basilar artery aneurysm. Case report.
abstract: Advances in anesthetic and surgical management, such as induced deep hypothermic circulatory arrest and application of temporary clips, have improved outcome for patients with basilar artery aneurysms. Nonetheless, these techniques are associated with significant risks. The authors report a case in which three transient periods of cardiac asystole were induced during basilar artery aneurysm surgery. Adenosine-induced asystole facilitated the safe clipping of the aneurysm by producing consistent periods of profound hypotension and collapse of the aneurysm without the need for temporary clipping. This technique provided unencumbered identification of perforating arteries, precise definition of the local anatomy, and an ideal environment for the safe placement of the aneurysm clip.
authors.affiliation: Department of Neurosurgery, Mount Sinai School of Medicine, New York, New York 10029, USA.
authors.forename: M W
authors.initials: MW
authors.lastname: Groff
authors.forename: D C
authors.initials: DC
authors.lastname: Adams
authors.forename: R A
authors.initials: RA
authors.lastname: Kahn
authors.forename: U M
authors.initials: UM
authors.lastname: Kumbar
authors.forename: B Y
authors.initials: BY
authors.lastname: Yang
authors.forename: J B
authors.initials: JB
authors.lastname: Bederson
mesh_terms: D000241:Adenosine / Q000627:therapeutic use*; D001488:Basilar Artery / Q000000981:diagnostic imaging / Q000601:surgery*; D001794:Blood Pressure; D002533:Cerebral Angiography; D004562:Electrocardiography; D004569:Electroencephalography; D001330:Electronic Data Processing; D005260:Female; D006324:Heart Arrest, Induced; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D008875:Middle Aged; D016343:Monitoring, Intraoperative
chemical_list: D000241:Adenosine