Meningoencephalitis caused by a novel paramyxovirus: an advanced MRI case report in an emerging disease.
Eleven abattoir workers in Singapore were infected in March 1999 by an outbreak caused by the Nipah virus. This newly discovered, Hendra-like paramyxovirus causes acute infection of the CNS. We present the magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (MRS) findings in a patient suffering from acute meningoencephalitis. Multiple small white matter lesions were detected on diffusion-weighted imaging (DWI) and T2-weighted images. There were no abnormalities detected on MRS. We believe this to be the first reported MRI findings in this novel zoonotic viral disease.
Lim
C C
CC
Department of Diagnostic Imaging, Tan Tock Seng Hospital, Singapore.
Sitoh
Y Y
YY
Lee
K E
KE
Kurup
A
A
Hui
F
F
D000003:Abattoirs; D000328:Adult; D000818:Animals; D001921:Brain / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis* / Q000821:virology*; D016272:Occupational Health; D018108:Respirovirus / Q000472:pathogenicity; D010253:Respirovirus Infections / Q000175:diagnosis*; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis / Q000821:virology; D015047:Zoonoses