title: Melkersson-Rosenthal syndrome in childhood: successful management with combination steroid and minocycline therapy.
abstract: The Melkersson-Rosenthal syndrome consists of a triad of recurrent lip and/or face swelling, fissured tongue, and intermittent facial palsy. Onset of the symptoms may occur during childhood, and treatment of the condition is difficult. We describe two children with Melkersson-Rosenthal syndrome in whom combination treatment with prednisone and minocycline proved effective and well tolerated.
authors.affiliation: Department of Dermatology, Northwestern University Medical School, Children's Memorial Hospital, Chicago, Illinois, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Stein
authors.forename: A J
authors.initials: AJ
authors.lastname: Mancini
mesh_terms: D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008556:Melkersson-Rosenthal Syndrome / Q000188:drug therapy*; D008911:Minocycline / Q000627:therapeutic use*; D011241:Prednisone / Q000627:therapeutic use*
chemical_list: D005938:Glucocorticoids; D008911:Minocycline; D011241:Prednisone