title: A missense mutation in both hMSH2 and APC in an Ashkenazi Jewish HNPCC kindred: implications for clinical screening.
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Yuan
authors.forename: N
authors.initials: N
authors.lastname: Wong
authors.forename: W D
authors.initials: WD
authors.lastname: Foulkes
authors.forename: L
authors.initials: L
authors.lastname: Alpert
authors.forename: F
authors.initials: F
authors.lastname: Manganaro
authors.forename: C
authors.initials: C
authors.lastname: Andreutti-Zaugg
authors.forename: R
authors.initials: R
authors.lastname: Iggo
authors.forename: K
authors.initials: K
authors.lastname: Anthony
authors.forename: E
authors.initials: E
authors.lastname: Hsieh
authors.forename: M
authors.initials: M
authors.lastname: Redston
authors.forename: L
authors.initials: L
authors.lastname: Pinsky
authors.forename: M
authors.initials: M
authors.lastname: Trifiro
authors.forename: P H
authors.initials: PH
authors.lastname: Gordon
authors.forename: D
authors.initials: D
authors.lastname: Lasko
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D025601:Adenomatous Polyposis Coli Protein; D002352:Carrier Proteins; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000235:genetics*; D003598:Cytoskeletal Proteins / Q000235:genetics*; D004268:DNA-Binding Proteins; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007585:Jews; D008297:Male; D018895:Microsatellite Repeats; D000070957:MutL Protein Homolog 1; D051718:MutS Homolog 2 Protein; D020125:Mutation, Missense; D009363:Neoplasm Proteins / Q000235:genetics; D009687:Nuclear Proteins; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D010375:Pedigree; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D012307:Risk Factors
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D025601:Adenomatous Polyposis Coli Protein; D002352:Carrier Proteins; D003598:Cytoskeletal Proteins; D004268:DNA-Binding Proteins; C501486:MLH1 protein, human; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; D011518:Proto-Oncogene Proteins; C497172:MSH2 protein, human; D000070957:MutL Protein Homolog 1; D051718:MutS Homolog 2 Protein