title: HLA-DQ1 associated with reflex sympathetic dystrophy.
abstract: Reflex sympathetic dystrophy (RSD) is a relatively common disabling disorder of unknown pathophysiology. From a cohort of 52 patients, carefully selected to fulfill the recently formulated diagnostic criteria for RSD, venous blood samples were taken for typing of class I and II major histocompatibility antigens. The frequency of HLA-DQ1 was found to be significantly increased compared with control frequencies. The association provides an indication for an organic basis of RSD.
authors.affiliation: Department of Surgery, Maastricht University Hospital, The Netherlands.
authors.forename: M A
authors.initials: MA
authors.lastname: Kemler
authors.forename: A C
authors.initials: AC
authors.lastname: van de Vusse
authors.forename: E M
authors.initials: EM
authors.lastname: van den Berg-Loonen
authors.forename: G A
authors.initials: GA
authors.lastname: Barendse
authors.forename: M
authors.initials: M
authors.lastname: van Kleef
authors.forename: W E
authors.initials: WE
authors.lastname: Weber
mesh_terms: D006683:HLA-DQ Antigens / Q000276:immunology*; D006801:Humans; D012019:Reflex Sympathetic Dystrophy / Q000276:immunology*
chemical_list: D006683:HLA-DQ Antigens; C051568:HLA-DQ1 antigen