Hepatic sarcoidosis responding to chloroquine as steroid-sparing drug.
We report a 59-year-old lady who presented with exertional dyspnea and was diagnosed to have sarcoidosis. She responded to steroids, but one year later developed abdominal symptoms and was found to have hepatosplenomegaly. Liver biopsy showed non caseating granulomas. As she had developed steroid-induced diabetes she was started on chloroquine and responded well with regression of the liver and spleen during one year of treatment.
Galwankar
S
S
Department of Medicine, P D Hinduja National Hospital and Medical Research Center, Mumbai.
Vyas
M
M
Desai
D
D
Udwadia
Z F
ZF
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002738:Chloroquine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D012507:Sarcoidosis / Q000188:drug therapy* / Q000473:pathology
D000893:Anti-Inflammatory Agents; D002738:Chloroquine; D011239:Prednisolone