title: Fatal and near-fatal asthma questionnaire: prelude to a national registry.
abstract: BACKGROUND
  Asthma mortality rates continue to be unacceptably high in the United States. As a follow-up to the initiatives proposed by the Asthma Mortality Task Force in 1987, the Committee on Asthma Mortality of the American Academy of Allergy, Asthma, and Immunology developed a questionnaire on fatal and near-fatal asthma.
  
  
  OBJECTIVE
  This study assessed completeness of answers from participating physicians and described characteristics of patients with fatal and near-fatal asthma.
  
  
  METHODS
  There were 111 survey items intended to characterize patients with fatal or near-fatal exacerbations of asthma. The questionnaire was sent to the members of the American Academy of Allergy, Asthma, and Immunology (approximately 3900), and a total of 143 usable questionnaires were received.
  
  
  RESULTS
  Responding physicians had information on most items in the questionnaire; the mean number of responses was 120 of 143 possible, with a median of 128 and a range of 40 to 143. Patient demographics, description of the event, identification of overall risk for the event, use of medications, and characteristics of asthma management had the most complete responses (median response rates were 126-143). Presence of factors contributing to the event had fewer responses (range, 44-125). The physicians frequently had information on some psychologic characteristics (eg, 108 responses for depression and/or hopelessness and 127 responses for social support) but less information on several others (eg, 62 responses for family dysfunction). Statistical analysis of the completed surveys indicated that only 2 characteristics distinguished fatal from near-fatal asthma: progression in minutes (adjusted odds ratio, 4. 89; 95% confidence interval, 2.05-12.90) and absence of a past history of intubation (adjusted odds ratio, 3.55; 95% confidence interval, 1.55-8.97).
  
  
  CONCLUSIONS
  There is a need to gather further data on patients with fatal and near-fatal events to design appropriate prospective studies on asthma morbidity and mortality rates. Physicians can contribute important information about these patients. Gathering such data would be enhanced by establishing a national registry on fatal and near-fatal asthma.
authors.affiliation: Department of Pediatrics, Washington University School of Medicine, St Louis, MO, USA.
authors.forename: R C
authors.initials: RC
authors.lastname: Strunk
authors.forename: R A
authors.initials: RA
authors.lastname: Nicklas
authors.forename: H
authors.initials: H
authors.lastname: Milgrom
authors.forename: D
authors.initials: D
authors.lastname: Ikle
mesh_terms: D018926:Anti-Allergic Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000401:mortality*; D003710:Demography; D005260:Female; D006801:Humans; D008297:Male; D011159:Population Surveillance / Q000379:methods*; D012042:Registries; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014481:United States
chemical_list: D018926:Anti-Allergic Agents