title: Uniquely folded mini-protein motifs.
abstract: Mini-proteins containing fewer than 40 amino acids provide simple model systems for studying protein folding and stability as well as serving as scaffolds for the rational design of new functional motifs. This article reviews current progress on the design and characterization of discretely folded mini-protein motifs.
authors.affiliation: Deapartment of Chemistry, Massachusetts, Institute of Technology, Cambridge 02139, USA.
authors.forename: B
authors.initials: B
authors.lastname: Imperiali
authors.forename: J J
authors.initials: JJ
authors.lastname: Ottesen
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D002352:Carrier Proteins / Q000737:chemistry; D018999:Charybdotoxin / Q000031:analogs & derivatives / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008840:Microfilament Proteins / Q000737:chemistry; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry; D015202:Protein Engineering / Q000379:methods; D017510:Protein Folding; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry
chemical_list: D002352:Carrier Proteins; D008840:Microfilament Proteins; D010455:Peptides; D011506:Proteins; C113273:betanova protein, synthetic; C026615:villin; D018999:Charybdotoxin