title: Pyoderma gangrenosum. A diagnosis not to be missed.
abstract: We describe a case of pyoderma gangrenosum which presented with severe wound breakdown after elective hip replacement. The patient was treated successfully with minimal wound debridement and steroids. This diagnosis should always be considered when confronted with an enlarging painful skin lesion which does not grow organisms when cultured and fails to respond to antibiotic therapy, especially if there are similar lesions in other sites. In patients who have a past history of pyoderma gangrenosum, prophylactic steroids may be indicated at the time of surgery or may be required early in the postoperative period.
authors.affiliation: Nuffield Orthopaedic Centre, Headington, Oxford, England, UK.
authors.forename: P M
authors.initials: PM
authors.lastname: Armstrong
authors.forename: I
authors.initials: I
authors.lastname: Ilyas
authors.forename: R
authors.initials: R
authors.lastname: Pandey
authors.forename: A R
authors.initials: AR
authors.lastname: Berendt
authors.forename: C P
authors.initials: CP
authors.lastname: Conlon
authors.forename: A H
authors.initials: AH
authors.lastname: Simpson
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects; D003646:Debridement; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy
chemical_list: D011239:Prednisolone