1,2-Hydride Shift in the Biosynthesis of Pinguisane-type Sesquiterpenes.
A (2)H-NMR analysis of 6α-hydroxy-3-oxo-pinguis-5(10)-ene-11,6-olide produced by axenic culture of liverwort Aneura pinguis in the presence of [4-(2)H2]-labeled mevalonate clarified the presence of a 1,2-hydride shift and retention of deuterium at the C-4 position in the biosynthesis of pinguisane-type sesquiterpenes from FPP.
Tazaki
H
H
a Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine.
Iwasaki
T
T
a Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine.
Kawakami
Y
Y
b Basic Research Div. 3, Takasago International Corporation.
Nabeta
K
K
a Department of Bioresource Science, Obihiro University of Agriculture and Veterinary Medicine.