Refraction-enhanced x-ray imaging of mouse lung using synchrotron radiation source.
The low divergent x-ray beam from the third-generation synchrotron radiation source such as SPring-8 enables us to observe refraction of x rays that is in the range of microradians. Under an experimental condition for which ray optics is a good approximation, we found that the refraction produces a high-contrast projection image of a mouse when it was recorded at 6.5 m behind the specimen. Especially, the lung is visualized far better than with the conventional imaging which utilizes absorption of x rays. This is a promising new technique for the diagnosis of diseases in the human lung with a low radiation dose.
Yagi
N
N
JASRI/SPring-8, Mikazuki, Sayo, Hyogo, Japan.
Suzuki
Y
Y
Umetani
K
K
Kohmura
Y
Y
Yamasaki
K
K
D000818:Animals; D007089:Image Enhancement / Q000379:methods*; D008168:Lung / Q000000981:diagnostic imaging*; D051379:Mice; D008819:Mice, Nude; D011829:Radiation Dosage; D011859:Radiography / Q000295:instrumentation* / Q000379:methods*; D014965:X-Rays