Evolution of the linear chromosomal DNA in Streptomyces: is genomic variability developmentally modulated?
Genome rearrangements are responsible for the variability observed at the ends of the chromosome among Streptomyces species. The characterization of mutators, which are stimulated for genome plasticity, and of mutants produced at different stages of development support the idea that genome instability is developmentally modulated.
Dary
A
A
Laboratoire de génétique et microbiologie associé à l'Institut national de la recherche agronomique (unité 952), faculté des sciences de l'université Henri Poincaré, Nancy 1, Vandoeuvre-Lès-Nancy, France. dary@scbiol.u-nancy.fr
Martin
P
P
Wenner
T
T
Leblond
P
P
Decaris
B
B
D002876:Chromosomes, Bacterial / Q000235:genetics*; D019143:Evolution, Molecular; D014644:Genetic Variation; D016680:Genome, Bacterial; D016296:Mutagenesis; D013302:Streptomyces / Q000235:genetics* / Q000254:growth & development