title: Successful treatment of Kimura's disease with cyclosporine.
abstract: We report the case of a 29-year-old Japanese woman presenting with recurring Kimura's disease. We began treatment with cyclosporine within 7 days, the nodular lesion had almost cleared. The cyclosporine dose was then gradually reduced and discontinued after 6 months. The patient was reassessed 18 months after the cessation of treatment and there was no evidence of recurrence of the disease. We speculate that the effects of cyclosporine on T helper-2 cells improves Kimura's disease.
authors.affiliation: Department of Dermatology, Nippon Medical School, Tokyo, Japan. pst@nms.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Kaneko
authors.forename: M
authors.initials: M
authors.lastname: Aoki
authors.forename: S
authors.initials: S
authors.lastname: Hattori
authors.forename: M
authors.initials: M
authors.lastname: Sato
authors.forename: S
authors.initials: S
authors.lastname: Kawana
mesh_terms: D000328:Adult; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000188:drug therapy* / Q000473:pathology; D016572:Cyclosporine / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004427:Ear Diseases / Q000188:drug therapy* / Q000473:pathology; D004431:Ear, External; D005260:Female; D006801:Humans
chemical_list: D003879:Dermatologic Agents; D016572:Cyclosporine