title: Valve surgery in octogenarians.
abstract: OBJECTIVE
  To review the outcomes of octogenarians undergoing valve operations.
  
  
  METHODS
  One hundred and twenty-five consecutive patients aged 80 years and over received valve operations between 1990 and 1996 at the Toronto General Hospital, Toronto, Ontario. All hospital survivors were prospectively followed for a mean of 36.6 months (range 0.1 to 89.9).
  
  
  RESULTS
  One hundred and two patients received aortic valve operations, 18 patients received mitral procedures and five patients underwent double valve operations. Significant aortic stenosis was present in 95 of 102 patients (93%) receiving isolated aortic valve surgery, and mitral regurgitation was present in 16 of 18 patients (89%) undergoing mitral valve operations. Overall in-hospital mortality was 6.4% (n=8) and the perioperative infarction rate was 1.6% (n=2). In-hospital mortality was higher for mitral valve patients at 17% (n=3) than for aortic valve patients at 4% (n=4) (P=0.06). For the group overall, the six-year actuarial survival rate was 71.6+/-6%. The actuarial freedom from valve-related death was 97.1+/-2% at three years. Concomitant coronary artery disease was not significantly associated with perioperative mortality. Survivors had significantly improved New York Heart Association functional class status.
  
  
  CONCLUSIONS
  In carefully selected patients aged 80 years and over, aortic valve surgery carries a low perioperative mortality with good intermediate term survival and benefits. Octogenarians undergoing mitral valve procedures experience higher perioperative mortality. Although the number of participants was small for this study, it does appear that coexistent coronary artery disease should not be the sole reason for denial of surgery because it has less of an impact on short and intermediate term survival than other factors.
authors.affiliation: Toronto General Hospital, Toronto, Canada. aralph-edwards@torhosp.toronto.on.ca
authors.forename: A C
authors.initials: AC
authors.lastname: Ralph-Edwards
authors.forename: A G
authors.initials: AG
authors.lastname: Robinson
authors.forename: R S
authors.initials: RS
authors.lastname: Gordon
authors.forename: J
authors.initials: J
authors.lastname: Ivanov
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000601:surgery; D005260:Female; D006333:Heart Failure / Q000150:complications*; D006349:Heart Valve Diseases / Q000209:etiology* / Q000601:surgery; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000601:surgery; D009203:Myocardial Infarction / Q000150:complications*; D016896:Treatment Outcome