title: Total Synthesis of (+/-)-Gelsemine.
abstract: A complex molecular reorganization (1-->2), a sequential anionic aza-Cope rearrangement and Mannich cyclization, and an unprecedented intramolecular Heck reaction of the tetrasubstituted double bond of a vinylogous carbamate are key steps in a new total synthesis of (+/-)-gelsemine (3). MOM=methoxymethyl, DBU=1,8-diazabicyclo[5.4.0]undec-7-ene.
authors.affiliation: Department of Chemistry, University of California, 516 Rowland Hall, Irvine, CA 92697-2025 (USA).
authors.initials: A
authors.lastname: Madin
authors.initials: CJ
authors.lastname: O'Donnell
authors.initials: T
authors.lastname: Oh
authors.initials: DW
authors.lastname: Old
authors.initials: LE
authors.lastname: Overman
authors.initials: MJ
authors.lastname: Sharp