title: The molecular perspective: methotrexate.
authors.affiliation: The Scripps Research Institute, Department of Molecular Biology, La Jolla, California 92037, USA.
authors.forename: D S
authors.initials: DS
authors.lastname: Goodsell
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000737:chemistry / Q000494:pharmacology*; D001665:Binding Sites; D005493:Folic Acid Antagonists / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D008727:Methotrexate / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D008958:Models, Molecular; D019384:Nucleic Acid Synthesis Inhibitors / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D013762:Tetrahydrofolate Dehydrogenase / Q000737:chemistry / Q000378:metabolism
chemical_list: D000964:Antimetabolites, Antineoplastic; D005493:Folic Acid Antagonists; D019384:Nucleic Acid Synthesis Inhibitors; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate