title: [Main principles of etiotropic therapy in chronic osteomyelitis].
abstract: The results of prospective trial in 352 patients treated surgically for chronic osteomyelitis were presented: 151 patients with hematogenous and 201--with posttraumatic osteomyelitis. Various antibacterial treatment modalities were used for sanation of fistulas and purulent foci--chemical antiseptics, ultrasound, laser, flowing--lavage drainage, immobilized antibacterial drugs on various filling materials. Bacteriological examinations, including verification of pathogens and quantitative measurement of microbes in the tissues, has definitely proved effectiveness of such combined methods of treatment. The author suggests that sanation of the purulent focus should be applied in all stages of surgical treatment for such patients: during preparation for surgery, intraoperatively and in postoperative period.
authors.forename: V K
authors.initials: VK
authors.lastname: Gostishchev
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D002908:Chronic Disease; D004322:Drainage; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D010019:Osteomyelitis / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D011182:Postoperative Care; D011446:Prospective Studies; D012086:Reoperation; D013997:Time Factors; D014464:Ultrasonic Therapy
chemical_list: D000891:Anti-Infective Agents, Local