title: Predictors of chronic post-traumatic stress disorder. A prospective study.
abstract: BACKGROUND
  Most individuals who, shortly after trauma, express symptoms of post-traumatic stress disorder (PTSD) recover within one year of their traumatic experiences. In contrast, those who remain ill for one year rarely recover completely. The early identification of the latter is, therefore, very important.
  
  
  OBJECTIVE
  To prospectively evaluate predictors of PTSD at four months and one year.
  
  
  METHODS
  We followed 236 trauma survivors recruited from admissions to a general hospital's emergency room for four months, at which point 41 (17.4%) met diagnostic criteria for PTSD. Twenty-three of these individuals, and 39 individuals without PTSD at four months, were assessed again at one year.
  
  
  RESULTS
  Depressive symptoms were the best predictors of PTSD at both time points. Intrusive symptoms and peri-traumatic dissociation were better at predicting four-month PTSD than one-year PTSD.
  
  
  CONCLUSIONS
  The occurrence of depression during the months that follow a traumatic event is an important mediator of chronicity in PTSD.
authors.affiliation: Center for Traumatic Stress, Hadassah University Hospital, Jerusalem, Israel.
authors.forename: S A
authors.initials: SA
authors.lastname: Freedman
authors.forename: D
authors.initials: D
authors.lastname: Brandes
authors.forename: T
authors.initials: T
authors.lastname: Peri
authors.forename: A
authors.initials: A
authors.lastname: Shalev
mesh_terms: D000328:Adult; D005189:False Positive Reactions; D005260:Female; D005544:Forecasting; D006801:Humans; D008016:Life Change Events; D008297:Male; D011237:Predictive Value of Tests; D015995:Prevalence; D011379:Prognosis; D011446:Prospective Studies; D012372:ROC Curve; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis*