title: Laser treatment in eyes with drusen.
abstract: During the past several decades, many individuals have noted that drusen may resolve after macular laser photocoagulation. The lack of effective therapies against choroidal neovascularization (CNV) due to age-related macular degeneration (AMD) has prompted many invesigators to explore strategies designed to prevent CNV in eyes with high-risk drusen. Currently, several pilot studies in the United States, Spain, Sweden, Australia, and the United Kingdom are in progress; the Choroidal Neovascularization Prevention Trial (CNVPT) is the largest pilot study to date and is detailed herein. A definitive study, the Complications of Age-Related Macular Degeneration Prevention Trial, aims to evaluate the effects of laser treatment in patients with bilateral drusen and will commence this year.
authors.affiliation: Wills Eye Hospital, Philadelphia, Pennsylvania, USA. acho@att.net
authors.forename: A C
authors.initials: AC
authors.lastname: Ho
mesh_terms: D020256:Choroidal Neovascularization / Q000209:etiology / Q000517:prevention & control; D002986:Clinical Trials as Topic; D006801:Humans; D017075:Laser Coagulation; D015593:Retinal Drusen / Q000150:complications / Q000473:pathology / Q000601:surgery*