Praziquantel for treatment of malaria.
The possible effect of oral praziquantel on malaria parasites was studied. Nine patients with P. falciparum and one patient with P. vivax were treated with 30 mg/kg/day of praziquantel in three divided doses for a maximum of 8 days. The results showed that eight patients had complete cure within 4-6 days of using praziquantel. Two patients with P. falciparum complicated by jaundice and severe anemia showed no response and required antimalarial drugs. One patient had bloody diarrhoea. It could be concluded that praziquantel might represent a new line for treatment of malaria.
al-Waili
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NS
Dubai Medical College, United Arab Emirates.
D000293:Adolescent; D000328:Adult; D000871:Anthelmintics / Q000627:therapeutic use*; D000962:Antimalarials / Q000627:therapeutic use*; D002648:Child; D005260:Female; D006801:Humans; D008288:Malaria / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use*; D016896:Treatment Outcome
D000871:Anthelmintics; D000962:Antimalarials; D011223:Praziquantel