title: Efficacy and mode of action of an immunomodulator herbal preparation containing Echinacea, wild indigo, and white cedar.
abstract: Using the example of an allopathic herbal combined preparation containing Echinacea root, wild indigo root, and white cedar leaf tips (Echinaceae radix + Baptisiae tinctoriae radix + Thujae occidentalis herba = Esberitox N), the efficacy and mode of action of a phytoimmunomodulator, or immune system enhancer, is described. Efficacy of the immunomodulator has been demonstrated in studies of acute viral respiratory tract infections and infections requiring antibiotic therapy. In a recent study compliant to GCP, the therapeutic superiority of the herbal immunomodulator over placebo was confirmed as statistically significant and clinically relevant. The present overview describes a model of the antigen-independent mode of action of phytoimmunomodulation ("immunobalancing").
authors.forename: P
authors.initials: P
authors.lastname: Wüstenberg
authors.forename: H H
authors.initials: HH
authors.lastname: Henneicke-von Zepelin
authors.forename: G
authors.initials: G
authors.lastname: Köhler
authors.forename: U
authors.initials: U
authors.lastname: Stammwitz
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003139:Common Cold / Q000188:drug therapy; D004338:Drug Combinations; D006801:Humans; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D010946:Plants, Medicinal / Q000737:chemistry; D012141:Respiratory Tract Infections / Q000188:drug therapy
chemical_list: D000276:Adjuvants, Immunologic; D004338:Drug Combinations; D010936:Plant Extracts