title: Involution of enhancing intrinsic tectal tumors after endoscopic third ventriculostomy. Report of two cases.
abstract: For benign intrinsic tectal tumors causing triventricular obstructive hydrocephalus, cerebrospinal fluid diversion followed by neuroimaging is a widely accepted treatment plan. In this report, the authors describe two children with focal enhancing tectal lesions that caused acute, symptomatic hydrocephalus. One child had neurofibromatosis Type 1 (NF1). In both children the hydrocephalus was effectively treated by endoscopic third ventriculostomy. Following this procedure, serial imaging studies revealed not only that the ventriculomegaly had resolved, but also that the enhancing tectal tumors had regressed and disappeared over time. The time to complete involution of these tumors was 18 months for the child with NF1 and 12 months for the other child. To the authors' knowledge, this is the first report of the involution of enhancing tectal tumors after endoscopic third ventriculostomy. The possible mechanisms for this unexpected result are discussed.
authors.affiliation: Division of Neurosurgery, The Hospital for Sick Children, University of Toronto, Ontario, Canada.
authors.forename: A M
authors.initials: AM
authors.lastname: Alkhani
authors.forename: F A
authors.initials: FA
authors.lastname: Boop
authors.forename: J T
authors.initials: JT
authors.lastname: Rutka
mesh_terms: D000208:Acute Disease; D002648:Child; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005682:Gadolinium; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D017253:Neurofibromatoses / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D020542:Third Ventricle / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D014696:Ventriculostomy
chemical_list: D005682:Gadolinium