Current issues in colorectal cancer surgery.
Increased understanding of the pathology and natural history of colorectal cancer has led to significant advances in the management of this disease. Surgical management of rectal cancer currently includes a spectrum of operative procedures ranging from radical operations to innovative sphincter-preserving techniques. At one end of the spectrum, 5% to 10% of patients present with small, superficially invasive rectal cancers amenable to a curative local excision. At the other end, a subset of patients present with locally advanced rectal cancers that require multimodality therapy, including sharp pelvic dissection with en-bloc resection of involved organs. However, the majority of rectal cancer patients present with nonfixed, yet deeply invasive, lesions requiring either a low anterior resection (LAR) or an abdominal perineal resection (APR). This report will address the controversies in the surgical management of colorectal cancer.
Guillem
J G
JG
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Cohen
A M
AM
D000714:Anastomosis, Surgical; D017776:Autonomic Pathways; D003106:Colon / Q000294:innervation / Q000601:surgery; D015179:Colorectal Neoplasms / Q000601:surgery*; D003107:Colorectal Surgery / Q000639:trends*; D003131:Combined Modality Therapy; D006801:Humans; D010535:Laparoscopy; D008197:Lymph Node Excision; D016737:Proctocolectomy, Restorative; D012007:Rectum / Q000294:innervation / Q000601:surgery