title: Cytoskeleton: centrosom-in absentia.
abstract: Recent results challenge long-held assumptions that centrosomes are essential organizers of mitotic spindles, but suggest that they couple spindle behavior with developmental and cellular events, perhaps by nucleating astral microtubules which mediate interactions with other cytoskeletal components.
authors.affiliation: Department of Biochemistry and Biophysics, University of California at San Francisco San Francisco, California 94143-0448, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: Vidwans
authors.forename: P H
authors.initials: PH
authors.lastname: O'Farrell
mesh_terms: D000818:Animals; D018385:Centrosome / Q000502:physiology*; D003599:Cytoskeleton / Q000502:physiology*; D004330:Drosophila / Q000196:embryology / Q000235:genetics / Q000502:physiology; D029721:Drosophila Proteins; D018398:Homeodomain Proteins / Q000235:genetics / Q000502:physiology; D019476:Insect Proteins / Q000235:genetics / Q000502:physiology; D008870:Microtubules / Q000502:physiology; D008938:Mitosis; D009154:Mutation; D008941:Spindle Apparatus / Q000502:physiology
chemical_list: D029721:Drosophila Proteins; D018398:Homeodomain Proteins; D019476:Insect Proteins; C098130:cnn protein, Drosophila