title: Selective ablation of porcine and rabbit liver tissue using radiofrequency: preclinical study.
abstract: Temperature changes and their distribution induced by 13.56-MHz radiofrequency (RF) heating of agar phantom and porcine and rabbit liver were investigated. It was possible to produce selective local heating of approximately 50 degrees C in the RF field of 2 x 2 x 2 cm(3) of the pig or rabbit liver. Coagulation necrosis after heating became pronounced and the margin between the coagulated lesion and normal tissue became clearer with time. Within 1 week after RF heating at 50 degrees C for 20 min, the coagulated area was replaced selectively and totally by necrotic tissue.
authors.affiliation: First Department of Surgery, Kansai Medical University, Osaka, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Nakagawa
authors.forename: Y
authors.initials: Y
authors.lastname: Kamiyama
authors.forename: Y
authors.initials: Y
authors.lastname: Matsui
authors.forename: M
authors.initials: M
authors.lastname: Nakagawa
authors.forename: H
authors.initials: H
authors.lastname: Araki
authors.forename: S
authors.initials: S
authors.lastname: Kasamatsu
authors.forename: T
authors.initials: T
authors.lastname: Wei
authors.forename: Y
authors.initials: Y
authors.lastname: Okuda
authors.forename: H
authors.initials: H
authors.lastname: Kitade
authors.forename: T
authors.initials: T
authors.lastname: Kamiya
authors.forename: T
authors.initials: T
authors.lastname: Noro
authors.forename: N
authors.initials: N
authors.lastname: Kubo
authors.forename: Y
authors.initials: Y
authors.lastname: Nakase
mesh_terms: D000818:Animals; D017115:Catheter Ablation; D006358:Hot Temperature; D008099:Liver / Q000473:pathology / Q000601:surgery*; D009336:Necrosis; D019047:Phantoms, Imaging; D011817:Rabbits; D013552:Swine; D013696:Temperature