title: [Substituted thiazolidinediones and thioxothiazolidinones: synthesis and structure].
abstract: Synthesis and physico-chemical properties of 3-(4-bromobenzyl)-, 3-(4-chlorobenzyl)-5-arylidene-thiazolidine-2,4-diones and 3-(4-chlorobenzyl)-4-thioxo-5-arylidene-thiazolidin-2- ones are described. Twelve new products were synthesized by the aldolisation-crotonisation reaction from aromatic aldehydes and N-alkylated thiazolidinediones or thioxothiazolidinones. Seven compounds were preliminary tested for their bacteriostatic activity.
authors.affiliation: Departamento de Antibióticos, Universidade Federal de Pernambuco, Recife, Brasil.
authors.forename: J F
authors.initials: JF
authors.lastname: Albuquerque
authors.forename: A M
authors.initials: AM
authors.lastname: Andrade
authors.forename: A L
authors.initials: AL
authors.lastname: Barros
authors.forename: M R
authors.initials: MR
authors.lastname: Nascimento
authors.forename: E A
authors.initials: EA
authors.lastname: Ximenes
authors.forename: S L
authors.initials: SL
authors.lastname: Galdino
authors.forename: I R
authors.initials: IR
authors.lastname: Pitta
authors.forename: M
authors.initials: M
authors.lastname: Perrissin
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D013844:Thiazoles