Translocation (X;5)(q13;q33) in essential thrombocythemia.
We report a novel chromosomal translocation (X;5)(q13;q33) in a woman with no history of prior chemotherapy or radiotherapy, found to have essential thrombocythemia. Aberrations in chromosome 5, mostly deletions of 5q, have been described in essential thrombocythemia; however, a t(X;5) translocation has not been reported.
Munro
L R
LR
Department of Haematology, Aberdeen Royal Infirmary, UK.
Stevenson
D A
DA
Culligan
D J
DJ
D002895:Chromosomes, Human, Pair 5; D005260:Female; D006801:Humans; D008875:Middle Aged; D013922:Thrombocytosis / Q000235:genetics*; D014178:Translocation, Genetic; D014960:X Chromosome