Review of quality-of-life evaluations in patients with angina pectoris.
Patients with angina pectoris have a reduced quality of life because of their symptoms, impaired activity and anxiety. However, there is no consensus on the best method of measuring quality of life. A systematic literature search of randomised controlled trials (RCTs) in angina showed that the most common generic questionnaire was the Nottingham Health Profile (NHP) Part 1, and the most common angina-specific measure was the Quality-of-Life after Acute Myocardial Infarction Questionnaire. A comparison of NHP scores with those of the healthy population revealed that patients with angina particularly seem to experience a lack of energy, poor sleep and decreased physical mobility. In the RCTs evaluated, antianginal drugs did not show a significant benefit over placebo in terms of quality of life. As a result of a lack of valid data from RCTs, a strong conclusion regarding the impact of revascularisation procedures on quality of life could not be derived.
Gandjour
A
A
Institute of Health Economics and Clinical Epidemiology, University of Cologne, Germany. afschin.gandjour@medizin.uni-koeln.de
Lauterbach
K W
KW
D000787:Angina Pectoris / Q000523:psychology*; D006801:Humans; D009203:Myocardial Infarction / Q000523:psychology; D011788:Quality of Life