[Multicomponent dressing media in treatment of suppurated wounds].
The multicomponent dressing medium (MDM) has been developed for treatment of festered wounds. The first layer consists of hydrofibrosed gauze with chlorhexidine being introduced into its structure in quantity of 0.2-0.5 mass %. The second layer of MDM is chlorhexidinum salt of monocarboxylcellulose with carboxyl group content of 12-22 mass % and chlorhexidine content being 1-2 mass %. The third layer is polyamide pellicle with the pores less than 1 micron in diameter. The created MDM possess significant capillar-transport, absorption, anti-adhesive and prolongated antimicrobial properties, prevents development of secondary infection and "hotbed" effect in the wound.
Abaev
Iu K
IuK
Kaputskiĭ
V E
VE
Adarchenko
A A
AA
D000293:Adolescent; D000818:Animals; D000891:Anti-Infective Agents, Local / Q000494:pharmacology; D001684:Biological Dressings; D002483:Cellulose, Oxidized / Q000494:pharmacology; D002648:Child; D002710:Chlorhexidine / Q000494:pharmacology; D004338:Drug Combinations; D006490:Hemostatics / Q000494:pharmacology; D006801:Humans; D051381:Rats; D017208:Rats, Wistar; D013492:Suppuration; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects; D014946:Wound Infection / Q000473:pathology / Q000628:therapy*
D000891:Anti-Infective Agents, Local; D002483:Cellulose, Oxidized; D004338:Drug Combinations; D006490:Hemostatics; D002710:Chlorhexidine