title: Knowledge of physician prescriptions and adherence to treatment among children with cystic fibrosis and their mothers.
abstract: This investigation examined factors related to adherence to treatment regimens for children with cystic fibrosis (CF) and their mothers. Subjects were 45 children with CF who ranged in age from 6 to 10 years and their mothers. Findings revealed that children's and parents' reports of level of adherence were related to their knowledge of the specific details associated with medically prescribed treatments. In this sample, 12% to 32% of mothers did not have an accurate understanding of physician recommendations for their children's treatments. When controlling for individual differences in the prescribed treatment regimens, parents' and children's knowledge of what had been prescribed accounted for a significant portion of the variance in the children's reported treatment-related behaviors. Results are discussed in terms of implications for future intervention research aimed at enhancing adherence to treatment as well as for future directions for clinical efforts in this area.
authors.affiliation: Department of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve School of Medicine, Cleveland, Ohio 44106-6038, USA.
authors.forename: C E
authors.initials: CE
authors.lastname: Ievers
authors.forename: R T
authors.initials: RT
authors.lastname: Brown
authors.forename: D
authors.initials: D
authors.lastname: Drotar
authors.forename: D
authors.initials: D
authors.lastname: Caplan
authors.forename: B S
authors.initials: BS
authors.lastname: Pishevar
authors.forename: R G
authors.initials: RG
authors.lastname: Lambert
mesh_terms: D001294:Attitude to Health; D002648:Child; D002652:Child Behavior / Q000523:psychology; D003071:Cognition; D003550:Cystic Fibrosis / Q000188:drug therapy*; D011307:Drug Prescriptions; D005260:Female; D006801:Humans; D008297:Male; D008425:Maternal Behavior / Q000523:psychology*; D009035:Mothers / Q000523:psychology*; D010349:Patient Compliance; D011795:Surveys and Questionnaires