Bilateral granulomatous panuveitis as initial presentation of diffuse systemic T cell lymphoma.
A high-grade diffuse T cell lymphoma, initially simulating bilateral panuveitis, was diagnosed by analysis of a vitreous biopsy specimen and a breast tumor in a 57-year-old woman. It responded favorably to aggressive chemotherapy before it relapsed in leukemic transformation. This case emphasizes the misleading initial symptoms of primary intraocular lymphoma and the role of immunophenotyping in the diagnosis and classification of lymphoproliferative ocular disorders. The presentation and management of uveal lymphoid neoplasia are discussed.
Goeminne
J C
JC
Hematology Department, Cliniques Universitaires St-Luc, Brussels, Belgium. goeminne@onco.ucl.ac.be
Brouillard
A
A
Jaumain
P
P
Ferrant
A
A
Snyers
B
B
De Potter
P
P
D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D016399:Lymphoma, T-Cell / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D015864:Panuveitis / Q000175:diagnosis / Q000209:etiology*; D014604:Uveal Neoplasms / Q000150:complications* / Q000175:diagnosis