Epithelioid blue nevus occurring in children with no evidence of Carney complex.
We report two pediatric patients who had biopsies of solitary lesions diagnosed as epithelioid blue nevi. Histologically these lesions had wedge-shaped, heavily pigmented infiltrates extending to the subcutaneous fat. The infiltrate was composed of spindled and polyhedral cells that were nevomelanocytic cells with nuclear pleomorphism. Also noted were pigmented globular cells interpreted as melanophages. These lesions have the same characteristics as those blue nevi occurring in patients with Carney complex. More recently, adult patients have been identified with similar nevi, but without evidence of Carney complex. To our knowledge, pediatric patients with epithelioid blue nevi, but no evidence of Carney complex have not been described previously.
O'Grady
T C
TC
Division of Dermatology, University of California, San Diego Medical Center San Diego, 92103-8420, USA.
Barr
R J
RJ
Billman
G
G
Cunningham
B B
BB
D002648:Child; D005260:Female; D006338:Heart Neoplasms / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D009232:Myxoma / Q000473:pathology; D018329:Nevus, Blue / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*