Spread of a Salmonella typhimurium clone resistant to expanded-spectrum cephalosporins in three European countries.
Twelve Salmonella typhimurium strains resistant to broad-spectrum cephalosporins were isolated from cases of gastroenteritis during 1996 to 1998 in Russia, Hungary, and Greece. Resistance was due to the production of CTX-M-type extended-spectrum beta-lactamases encoded by similar 12-kb plasmids. By pulsed-field gel electrophoresis, all strains shared the same chromosomal type. These data suggest that an S. typhimurium clone resistant to broad-spectrum cephalosporins is present in at least three European countries.
Tassios
P T
PT
Department of Microbiology, Medical School, University of Athens, Athens, Greece.
Gazouli
M
M
Tzelepi
E
E
Milch
H
H
Kozlova
N
N
Sidorenko
S
S
Legakis
N J
NJ
Tzouvelekis
L S
LS
D018550:Cephalosporin Resistance; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification; D016521:Electrophoresis, Gel, Pulsed-Field; D005759:Gastroenteritis / Q000382:microbiology; D006115:Greece; D006801:Humans; D006814:Hungary; D012426:Russia; D012480:Salmonella Infections / Q000382:microbiology; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification
D004269:DNA, Bacterial