title: [Debatable questions of surgical sepsis treatment and diagnosis].
abstract: On the basis of critical analysis of the results of combined treatment of 73 patients, the authors suggested that sepsis could be diagnosed only in the presence of systemic inflammatory response, multiorganic insufficiency and obligatory isolation of hemoculture. The microorganisms' specimen from the infected area and the blood are not identical both in primary and repeated inoculation. Impossibility to verify the pathogenic microorganism in the blood prevents from carrying out adequate and purposeful treatment. The absence of correlation between the severity of clinical course of sepsis, microflora species and laboratory immunography data, confirms the opinion that the organism responds to the inflammatory process by complex general physiologic reaction of defence, which includes, besides immunologic system, fermentative, endocrine, vegetative and other systems of homeostasis.
authors.forename: E A
authors.initials: EA
authors.lastname: Reshetnikov
authors.forename: G F
authors.initials: GF
authors.lastname: Shipilov
authors.forename: M V
authors.initials: MV
authors.lastname: Chuvanov
mesh_terms: D001419:Bacteria / Q000302:isolation & purification; D003937:Diagnosis, Differential; D006801:Humans; D018805:Sepsis / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D012720:Severity of Illness Index; D013530:Surgical Wound Infection / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D016896:Treatment Outcome