title: Cutaneous signs of selected systemic diseases.
abstract: In this work we will discuss three cutaneous markers of systemic disease. Acanthosis nigricans is the most widely known in this category. Cutaneous angiokeratomas are usually associated with enzyme defect disorders, such as Fabry's disease, and are linked in this work as a reactive pattern in hepatorenal failure. Mast cell disease may occur in a number of forms, often with systemic involvement.
authors.affiliation: Dermatology, New Jersey Medical School, Newark 07103-2714, USA.
authors.forename: N I
authors.initials: NI
authors.lastname: Kihiczak
authors.forename: C B
authors.initials: CB
authors.lastname: Leevy
authors.forename: M M
authors.initials: MM
authors.lastname: Krysicki
authors.forename: C K
authors.initials: CK
authors.lastname: Janniger
authors.forename: I
authors.initials: I
authors.lastname: Schneider
authors.forename: D L
authors.initials: DL
authors.lastname: Shriner
authors.forename: W C
authors.initials: WC
authors.lastname: Lambert
authors.forename: R A
authors.initials: RA
authors.lastname: Schwartz
mesh_terms: D000052:Acanthosis Nigricans / Q000175:diagnosis / Q000209:etiology; D000794:Angiokeratoma / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D017093:Liver Failure / Q000150:complications*; D008415:Mastocytosis / Q000175:diagnosis / Q000209:etiology; D051437:Renal Insufficiency / Q000150:complications*; D012871:Skin Diseases / Q000175:diagnosis / Q000209:etiology*; D012878:Skin Neoplasms / Q000209:etiology