Septicemia in neutropenic patients infected with Clostridium tertium resistant to cefepime and other expanded-spectrum cephalosporins.
Clostridium tertium was isolated from two immunocompromised patients with septicemia, fever, and gastrointestinal symptoms. The strains were resistant to ceftazidime, cefepime, and clindamycin; intermediately resistant to penicillin; and susceptible to metronidazole, quinolones, and vancomycin.
Steyaert
S
S
Department of Clinical Chemistry, Microbiology and Immunology, University Hospital, 9000 Ghent, Belgium. Sophia.Steyaert@rug.ac.be
Peleman
R
R
Vaneechoutte
M
M
De Baere
T
T
Claeys
G
G
Verschraegen
G
G
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000077723:Cefepime; D018550:Cephalosporin Resistance; D002511:Cephalosporins / Q000494:pharmacology*; D003013:Clostridium / Q000187:drug effects* / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000188:drug therapy / Q000382:microbiology; D009894:Opportunistic Infections / Q000188:drug therapy / Q000382:microbiology; D018805:Sepsis / Q000188:drug therapy / Q000382:microbiology*; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D014640:Vancomycin; D000077723:Cefepime