title: N,N-Diethanolaminomethyl Polystyrene: An Efficient Solid Support to Immobilize Boronic Acids.
abstract: The key to the efficiency of N,N-diethanolaminomethyl polystyrene (DEAM-PS), the first solid support capable of coupling to boronic acids, is the formation of a stable, resin-bound boronic ester ate adduct (see scheme). With this resin it is now possible to efficiently immobilize a wide variety of boronic acids including functionalized ones that can be derivatized by solid-phase combinatorial synthesis.
authors.affiliation: Department of Chemistry, University of Alberta, Edmonton, AB, T6G 2G2 (Canada).
authors.initials: DG
authors.lastname: Hall
authors.initials: J
authors.lastname: Tailor
authors.initials: M
authors.lastname: Gravel