title: Unusual eruption as a presenting symptom of cat scratch disease.
abstract: Cat scratch disease (CSD) is a common infectious cause of subacute regional lymphadenopathy. Bartonella henselae is the principal etiologic agent. About 10% of CSD patients experience atypical manifestations, including rashes. The most common cutaneous manifestation of CSD is a papule at the inoculation site. We report a case of CSD presenting with an eruption on the upper trunk, reminiscent of Sweet's syndrome, accompanied by lymphadenopathy, arthralgia, and fever. Response to systemic corticosteroids was remarkable. Histopathologic findings refuted the diagnosis of Sweet's syndrome. Identification of anti-B henselae antibodies and B henselae DNA in the affected lymph node confirmed the diagnosis of CSD. This is a first report of extensive papuloedematous eruption as a cutaneous manifestation of CSD. Accurate diagnosis is possible due to the availability of serological tests and DNA amplification techniques.
authors.affiliation: Department of Dermatology, Tel Aviv-Elias Sourasky Medical Center, and Sackler School of Medicine, Tel Aviv University, Israel. olandau@ibm.net
authors.forename: M
authors.initials: M
authors.lastname: Landau
authors.forename: Y
authors.initials: Y
authors.lastname: Kletter
authors.forename: B
authors.initials: B
authors.lastname: Avidor
authors.forename: G
authors.initials: G
authors.lastname: Ephrat
authors.forename: M
authors.initials: M
authors.lastname: Ephros
authors.forename: S
authors.initials: S
authors.lastname: Brenner
authors.forename: M
authors.initials: M
authors.lastname: Giladi
mesh_terms: D000328:Adult; D018416:Bartonella henselae; D002372:Cat-Scratch Disease / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D012871:Skin Diseases / Q000175:diagnosis* / Q000473:pathology; D016463:Sweet Syndrome / Q000175:diagnosis