Helicobacter pylori: novel therapies.
The ideal therapy for Helicobacter pylori would cure the infection without resulting in the development of antibiotic resistance. Current therapies have variable cure rates; the reasons for treatment failure include bacterial resistance and poor compliance. Some antibiotics, such as furazolidone, may be affordable agents to treat this infection worldwide. New proton pump inhibitors, such as rabeprazole, can potentiate antibiotics. Nutriceuticals and probiotics demonstrate interesting in vitro activity against H pylori. Children rarely have symptoms to this infection and, therefore, are a suitable group in which to assess different nonaggressive therapies.
Drouin
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Division of Gastroenterology, Hôpital Ste-Justine, University of Montreal, Quebec, Canada. edrouin@ibm.net
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D002211:Capsaicin; D002648:Child; D004359:Drug Therapy, Combination; D005737:Garlic; D005767:Gastrointestinal Diseases / Q000382:microbiology*; D016481:Helicobacter Infections / Q000188:drug therapy / Q000628:therapy*; D016480:Helicobacter pylori / Q000187:drug effects; D006722:Honey; D006801:Humans; D010946:Plants, Medicinal; D019936:Probiotics
D000900:Anti-Bacterial Agents; D000897:Anti-Ulcer Agents; D002211:Capsaicin