title: The relationship between pityriasis rubra pilaris and inflammatory arthritis: case report and response of the arthritis to anti-tumor necrosis factor immunotherapy.
abstract: Pityriasis rubra pilaris (PRP) refers to a group of erythematous, scaling dermatologic conditions that have been associated with seronegative arthritis. We report a case of polyarthritis in a young man with PRP in which magnetic resonance imaging suggested an entheseal-based pathology for the joint disease. The arthritis, but not the skin condition, demonstrated dramatic response to anti-tumor necrosis factor immunotherapy.
authors.affiliation: University of Leeds, UK.
authors.forename: P G
authors.initials: PG
authors.lastname: Conaghan
authors.forename: S
authors.initials: S
authors.lastname: Sommer
authors.forename: D
authors.initials: D
authors.lastname: McGonagle
authors.forename: D
authors.initials: D
authors.lastname: Veale
authors.forename: H
authors.initials: H
authors.lastname: Waldmann
authors.forename: G
authors.initials: G
authors.lastname: Hale
authors.forename: M
authors.initials: M
authors.lastname: Goodfield
authors.forename: P
authors.initials: P
authors.lastname: Emery
authors.forename: J
authors.initials: J
authors.lastname: Isaacs
mesh_terms: D000293:Adolescent; D000906:Antibodies / Q000627:therapeutic use; D001168:Arthritis / Q000150:complications* / Q000628:therapy; D016860:CD4 Immunoadhesins / Q000627:therapeutic use; D006801:Humans; D007167:Immunotherapy; D008297:Male; D010916:Pityriasis Rubra Pilaris / Q000150:complications*; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology
chemical_list: D000906:Antibodies; D016860:CD4 Immunoadhesins; D014409:Tumor Necrosis Factor-alpha