title: Dihydropyrimidine dehydrogenase: its role in 5-fluorouracil clinical toxicity and tumor resistance.
authors.forename: R B
authors.initials: RB
authors.lastname: Diasio
authors.forename: M R
authors.initials: MR
authors.lastname: Johnson
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D042943:Dihydrouracil Dehydrogenase (NADP); D019008:Drug Resistance, Neoplasm; D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D010088:Oxidoreductases / Q000502:physiology*
chemical_list: D000964:Antimetabolites, Antineoplastic; D010088:Oxidoreductases; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil