[Opsoclonus-myoclonus syndrome in the adult. 4 cases].
Four cases of opsoclonus in adults are reported. In all cases, it was associated with myoclonus and cerebellar syndrome. In 2 cases, the clinical and biological picture was suggestive of an infectious origin, and the patients recovered. The last cases are paraneoplastic opsoclonus revelating a pulmonary carcinoma and a breast cancer. The two patients died from metastasis after a transient improvement of ocular disorder. The pathophysiology of opsoclonus is discussed.
Khoris
J
J
Service de Neurologie A, CHU, Montpellier.
Pagès
M
M
D000230:Adenocarcinoma / Q000175:diagnosis; D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis; D002526:Cerebellar Diseases / Q000175:diagnosis; D003929:Diabetic Neuropathies / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009207:Myoclonus / Q000175:diagnosis*; D015835:Ocular Motility Disorders / Q000175:diagnosis*; D010257:Paraneoplastic Syndromes / Q000175:diagnosis