Coagulation factor Xa: the prothrombinase complex as an emerging therapeutic target for small molecule inhibitors.
Scarborough
R M
RM
Medicinal Chemistry Research, COR Therapeutics Inc., South San Francisco, CA 94080, USA. rscarborough@corr.com
D000925:Anticoagulants / Q000737:chemistry / Q000494:pharmacology; D000991:Antithrombins / Q000737:chemistry / Q000494:pharmacology; D001665:Binding Sites; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D005165:Factor V / Q000037:antagonists & inhibitors*; D015951:Factor Xa; D065427:Factor Xa Inhibitors; D006801:Humans; D015394:Molecular Structure
D000925:Anticoagulants; D000991:Antithrombins; D004791:Enzyme Inhibitors; D065427:Factor Xa Inhibitors; C022475:prothrombinase complex; D005165:Factor V; D015951:Factor Xa