Complications associated with percutaneous closure devices.
BACKGROUND
In an effort to reduce time to hemostasis after angiography, several closure devices have been marketed. We report some of their complications.


METHODS
A retrospective review was conducted.


RESULTS
Over an 8-month study period, 2,181 diagnostic and interventional procedures were performed. Closure devices were used in 408 (19%) of these patients. The Angio-Seal closure device is composed of a collagen sponge and an absorbable polymer anchor that compresses the hole in the arteriotomy. The ProstarXL sealing device consists of a rotating barrel that deploys 4 needles through the arteriotomy, and then individual knots are extracorporeally tied. The Duett device consists of a balloon occluding catheter and injectable collagen and thrombin. Ten of the patients developed a complication from the closure device (2.5%). Four of these were subcutaneous abscesses. Two of these patients had expanding pseudaneurysms, 2 had lower extremity ischemia, and 1 patient had an acute bleed. These complications were all managed surgically. Another patient developed a retroperitoneal bleed that was managed nonoperatively.


CONCLUSIONS
As the use of these devices increase, these complications will become more common.
Gonze
M D
MD
Department of Surgery, Ochsner Medical Institutions, New Orleans, Louisiana 70121, USA.
Sternbergh
W C
WC
Salartash
K
K
Money
S R
SR
D006489:Hemostatic Techniques / Q000009:adverse effects* / Q000295:instrumentation*; D006801:Humans; D012189:Retrospective Studies; D013536:Suture Techniques / Q000009:adverse effects* / Q000295:instrumentation*