Efficacy and mode of action of an immunomodulator herbal preparation containing Echinacea, wild indigo, and white cedar.
Using the example of an allopathic herbal combined preparation containing Echinacea root, wild indigo root, and white cedar leaf tips (Echinaceae radix + Baptisiae tinctoriae radix + Thujae occidentalis herba = Esberitox N), the efficacy and mode of action of a phytoimmunomodulator, or immune system enhancer, is described. Efficacy of the immunomodulator has been demonstrated in studies of acute viral respiratory tract infections and infections requiring antibiotic therapy. In a recent study compliant to GCP, the therapeutic superiority of the herbal immunomodulator over placebo was confirmed as statistically significant and clinically relevant. The present overview describes a model of the antigen-independent mode of action of phytoimmunomodulation ("immunobalancing").
Wüstenberg
P
P
Henneicke-von Zepelin
H H
HH
Köhler
G
G
Stammwitz
U
U
D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003139:Common Cold / Q000188:drug therapy; D004338:Drug Combinations; D006801:Humans; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D010946:Plants, Medicinal / Q000737:chemistry; D012141:Respiratory Tract Infections / Q000188:drug therapy
D000276:Adjuvants, Immunologic; D004338:Drug Combinations; D010936:Plant Extracts