[Clinical and immunomorphological parallels in posttraumatic uveitis].
Parallels between the clinical diagnosis, immunological parameters of the leukocyte migration inhibition test (LMIT) to eye tissue antigens (uveoretinal, lenticular, and retinal), and morphological picture are studied in patients with posttraumatic uveitis and consequences of grave penetrating injuries to the eye without uveitis symptoms. Cell sensitization to uveoretinal antigen is detected only in posttraumatic uveitis but not in consequences of injuries without uveitis. The authors come to a conclusion that only positive LMIT with uveoretinal or a combination of uveoretinal and lenticular antigens may be considered as an immunological validation of autoimmune posttraumatic uveitis. Further improvement of LMIT with purified fractions of uveoretinal antigens is needed.
Arkhipova
L T
LT
Khoroshilova-Maslova
I P
IP
Kuznetsova
I A
IA
Iluridze
S L
SL
D000293:Adolescent; D000328:Adult; D001324:Autoantigens / Q000276:immunology*; D015415:Biomarkers; D002464:Cell Migration Inhibition; D002465:Cell Movement / Q000276:immunology; D002648:Child; D015807:Eye Injuries, Penetrating / Q000150:complications* / Q000473:pathology; D005136:Eye Proteins / Q000276:immunology*; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000276:immunology / Q000293:injuries / Q000473:pathology; D007962:Leukocytes / Q000276:immunology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000276:immunology / Q000293:injuries / Q000473:pathology; D014602:Uvea / Q000276:immunology / Q000293:injuries* / Q000473:pathology; D014605:Uveitis / Q000209:etiology / Q000276:immunology* / Q000473:pathology
D001324:Autoantigens; D015415:Biomarkers; D005136:Eye Proteins