title: Intraluminal milrinone for dilation of the radial artery graft.
abstract: There is renewed interest in the use of the radial artery as a conduit for coronary artery bypass surgery. The radial artery is, however, a very muscular artery, prone to vasospasm. Milrinone, a potent vasodilator, has demonstrated vasodilatory properties superior to those of papaverine. In this report, we describe our technique of radial artery harvesting and the adjunctive use of intraluminal milrinone as a vasodilator in the preparation of this conduit for coronary artery bypass grafting. We have used these techniques in 25 patients who have undergone coronary artery bypass grafting using the radial artery. No hand ischemic complications have been observed in this group. Intraluminal milrinone appears to dilate and relax the radial artery, rendering this large conduit spasm free and very easy to use. We recommend the skeletonization technique for radial artery harvesting and the use of intraluminal milrinone as a radial artery vasodilator in routine myocardial revascularization.
authors.affiliation: The San Juan Group and the Department of Cardiovascular Surgery, Pavía Heart Institute, Puerto Rico 00910, USA.
authors.forename: R
authors.initials: R
authors.lastname: García-Rinaldi
authors.forename: E R
authors.initials: ER
authors.lastname: Soltero
authors.forename: J
authors.initials: J
authors.lastname: Carballido
authors.forename: J
authors.initials: J
authors.lastname: Mojica
mesh_terms: D000328:Adult; D000368:Aged; D001026:Coronary Artery Bypass / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020105:Milrinone / Q000008:administration & dosage / Q000627:therapeutic use*; D017534:Radial Artery / Q000187:drug effects / Q000637:transplantation*; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014665:Vasodilator Agents; D020105:Milrinone