title: Experiences with CCD detectors on a home X-ray source.
abstract: Charged-coupled device (CCD) detectors have been widely accepted as detectors for collecting X-ray diffraction images. The CCD detector offers a sensitive detection system well suited for diffraction analysis and, compared with other detectors on the market, a relatively rapid system for read-out of the collected image. The two predominant markets for the CCD detector have been those in which relatively short exposure times are used, i.e. small-molecule X-ray diffraction and large-molecule crystallography at high-intensity synchrotron sources. CCD detectors have not been commonly used on rotating-anode X-ray sources for large-molecule crystallography. Comparison of the performance of the CCD detectors with commercially available image-plate detectors shows that the CCD detectors function in a similar fashion to image-plate-based detectors.
authors.affiliation: Department of Structural Biology, Abbott Laboratories, D46Y, AP10, 100 Abbott Park Road, Abbott Park, IL 60064-3500, USA. muchmore@pprd.abbott.com
authors.forename: S W
authors.initials: SW
authors.lastname: Muchmore
mesh_terms: D018360:Crystallography, X-Ray / Q000295:instrumentation / Q000379:methods*; D009113:Muramidase / Q000737:chemistry; D011506:Proteins / Q000737:chemistry; D012984:Software
chemical_list: D011506:Proteins; D009113:Muramidase