Sulphated polysaccharides of Codium dwarkense Boergs. from the west coast of India: chemical composition and blood anticoagulant activity.
Bioassay-guided purification of sulphated polysaccharides from a green marine alga, Codium dwarkense, yielded two products, which contained sulphated arabinan and sulphated arabinogalactan. The product containing arabinan sulphate exhibited stronger blood anticoagulant activity than the one containing sulphated arabinogalactan.
Siddhanta
A K
AK
Marine Algae Discipline, Central Salt and Marine Chemicals Research Institute, Bhavnagar, India. salt@cscsmcri.ren.nic.in
Shanmugam
M
M
Mody
K H
KH
Goswami
A M
AM
Ramavat
B K
BK
D000925:Anticoagulants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000991:Antithrombins / Q000737:chemistry / Q000494:pharmacology; D001780:Blood Coagulation Tests; D000460:Chlorophyta / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D007194:India; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011134:Polysaccharides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D013431:Sulfates / Q000032:analysis / Q000737:chemistry
D000925:Anticoagulants; D000991:Antithrombins; D011134:Polysaccharides; D013431:Sulfates