[Comparative study of the use of sennoside A and B vs polyethylene glycol and electrolytes in anterograde preparation of the colon].
OBJECTIVE
Compare effectiveness of antegrade bowel preparation by liquid diet, polyethylenglycol (PEG) and electrolytes solution plus sennosides A and B, vs. liquid diet plus sennosides A and B only.


BACKGROUND
Preparation for colonoscopy with a balanced solution (PEG and electrolytes) has some physiological advantages. Nonetheless, drawbacks of such preparation include nasty flavor, large volumes and low availability in our country.


METHODS
A randomized, comparative, prospective, transversal and blind trial that included 200 patients scheduled for colonoscopy were randomly assigned (one hundred each group) to receive: group 1: liquid diet, sennosides A and B and a two litter of solution with PEG and electrolytes; and group 2: liquid diet plus sennosides A and B. Compliance, tolerance and effectiveness of both preparations were evaluated blindly. The results were assessed by Student's T test.


RESULTS
The effectiveness of group 2 preparation proved superior (p < 0.05) to group 1. Tolerance and side effects were similar for both groups with no related complications.
Farca Belsaguy
A
A
Servicio de Gastroenterología, Hospital Dr. Manuel Gea González, México, D.F.
Fernández Castro
E
E
Presenda Miller
F
F
D000880:Anthraquinones; D002400:Cathartics; D003113:Colonoscopy / Q000379:methods*; D004311:Double-Blind Method; D004573:Electrolytes; D006801:Humans; D011092:Polyethylene Glycols; D011446:Prospective Studies; D012676:Senna Extract / Q000737:chemistry*; D000081226:Sennosides; D012996:Solutions; D013501:Surface-Active Agents
D000880:Anthraquinones; D002400:Cathartics; D004573:Electrolytes; D000081226:Sennosides; D012996:Solutions; D013501:Surface-Active Agents; D011092:Polyethylene Glycols; D012676:Senna Extract