title: Speed of information processing as a key deficit in multiple sclerosis: implications for rehabilitation.
abstract: Speed of information processing was assessed in patients with multiple sclerosis and healthy controls using both an auditory and visual task designed to control for accuracy of performance across groups. After controlling for accuracy of performance, patients with multiple sclerosis were found to have significantly slower speed of information processing relative healthy controls, irrespective of the modality of stimulus presentation (auditory or visual). When given an adequate amount of time to process information, however, the patients performed similarly to controls. These results suggest that persons with multiple sclerosis experience deficits specifically in processing speed but not performance accuracy. Results are discussed in terms of rehabilitative guidelines for the cognitive improvement of persons with multiple sclerosis.
authors.affiliation: Kessler Medical Rehabilitation Research and Education Corporation, Neuropsychology and Neuroscience Laboratory, West Orange, NJ, USA.
authors.forename: H A
authors.initials: HA
authors.lastname: Demaree
authors.forename: J
authors.initials: J
authors.lastname: DeLuca
authors.forename: E A
authors.initials: EA
authors.lastname: Gaudino
authors.forename: B J
authors.initials: BJ
authors.lastname: Diamond
mesh_terms: D000328:Adult; D003072:Cognition Disorders / Q000145:classification* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008606:Mental Processes; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000523:psychology / Q000534:rehabilitation*; D011379:Prognosis; D013997:Time Factors