title: Unusual premature ovarian failure with hypogonadotropic hyperprolactinemia and 46, XX, 13ph+.
abstract: A 34-year-old woman with secondary amenorrhea is reported. She had a 30-day regular cycle menstruation from 12 to 24 years old. Her hormonal examination showed hypogonadotropic, secondary ovarian functional defect, and hyperprolactinemia. Her chromosomal arrangement was 46, XX, 13ph+ which is the elongation of 13p.
authors.affiliation: Department of Obstetrics and Gynecology, Gifu University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: T
authors.initials: T
authors.lastname: Tamaya
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000188:drug therapy; D001971:Bromocriptine / Q000627:therapeutic use; D002882:Chromosomes, Human, Pair 13; D002996:Clomiphene / Q000627:therapeutic use; D004965:Estrogen Antagonists / Q000627:therapeutic use; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D006062:Gonadotropins / Q000627:therapeutic use; D006727:Hormone Antagonists / Q000627:therapeutic use; D006801:Humans; D006966:Hyperprolactinemia / Q000188:drug therapy / Q000235:genetics*; D008598:Menstruation / Q000187:drug effects; D011247:Pregnancy; D016649:Primary Ovarian Insufficiency / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000235:genetics*; D014463:Ultrasonography
chemical_list: D004965:Estrogen Antagonists; D004967:Estrogens; D006062:Gonadotropins; D006727:Hormone Antagonists; D002996:Clomiphene; D001971:Bromocriptine