Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor.
Kaufman
R J
RJ
Howard Hughes Medical Institute, Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, MI 48105, USA. kaufmanr@umich.edu
D017209:Apoptosis; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D004686:Encephalomyocarditis virus / Q000254:growth & development*; D006801:Humans; D007372:Interferons / Q000378:metabolism; D008954:Models, Biological; D016328:NF-kappa B / Q000378:metabolism; D011494:Protein Kinases / Q000378:metabolism*; D012330:RNA, Double-Stranded / Q000378:metabolism*; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism; D020298:U937 Cells; D014775:Virus Activation; D019892:eIF-2 Kinase / Q000502:physiology*
D016328:NF-kappa B; D012330:RNA, Double-Stranded; D016159:Tumor Suppressor Protein p53; D007372:Interferons; D011494:Protein Kinases; D019892:eIF-2 Kinase