title: A nonhealing ulcer diagnosed as extramedullary plasmocytoma of the limb eight years after cardiac transplantation.
abstract: A 63-year-old man was hospitalized for a nonhealing ulcer of the left lower leg that appeared 8 years after orthotopic cardiac transplantation under immunosuppressive therapy including cyclosporine. Serum protein electrophoresis, immunofixation, and urinalysis revealed a monoclonal gammopathy IgG kappa. The final diagnosis of an extramedullary plasmocytoma was made by biopsy of the ulcer, which showed formations of plasmablastic cells. We report a rare case of extramedullary plasmocytoma as a posttransplantational malignancy.
authors.affiliation: Department of Medicine II, Johannes Gutenberg University, Mainz, Germany. Ibe@main.uni-mainz.de
authors.forename: W
authors.initials: W
authors.lastname: Ibe
authors.forename: T
authors.initials: T
authors.lastname: Wittlinger
authors.forename: M
authors.initials: M
authors.lastname: Sebastian
authors.forename: J
authors.initials: J
authors.lastname: Meyer
authors.forename: H
authors.initials: H
authors.lastname: Darius
mesh_terms: D016572:Cyclosporine / Q000627:therapeutic use; D006084:Graft Rejection / Q000517:prevention & control; D016027:Heart Transplantation / Q000009:adverse effects / Q000276:immunology / Q000473:pathology*; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007871:Leg Ulcer / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010954:Plasmacytoma / Q000175:diagnosis*; D012878:Skin Neoplasms / Q000175:diagnosis*
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine