title: Hydrogenosomes: eukaryotic adaptations to anaerobic environments.
abstract: Like mitochondria, hydrogenosomes compartmentalize crucial steps of eukaryotic energy metabolism; however, this compartmentalization differs substantially between mitochondriate aerobes and hydrogenosome-containing anaerobes. Because hydrogenosomes have arisen independently in different lineages of eukaryotic microorganisms, comparative analysis of the various types of hydrogenosomes can provide insights into the functional and evolutionary aspects of compartmentalized energy metabolism in unicellular eukaryotes.
authors.affiliation: Dept. of Microbiology and Evolutionary Biology, University of Nijmegen, Toernooiveld 1, NL-6525 ED Nijmegen, The Netherlands. hack@sci.kun.nl
authors.forename: J H
authors.initials: JH
authors.lastname: Hackstein
authors.forename: A
authors.initials: A
authors.lastname: Akhmanova
authors.forename: B
authors.initials: B
authors.lastname: Boxma
authors.forename: H R
authors.initials: HR
authors.lastname: Harhangi
authors.forename: F G
authors.initials: FG
authors.lastname: Voncken
mesh_terms: D000222:Adaptation, Physiological; D000332:Aerobiosis; D000693:Anaerobiosis; D002451:Cell Compartmentation; D004734:Energy Metabolism; D005057:Eukaryotic Cells / Q000378:metabolism* / Q000648:ultrastructure; D006859:Hydrogen / Q000378:metabolism*; D008928:Mitochondria; D015388:Organelles / Q000235:genetics* / Q000378:metabolism*
chemical_list: D006859:Hydrogen