title: Cogan's syndrome: an oculo-audiovestibular disease.
abstract: Typical Cogan's syndrome is a rare disease of young adults consisting of flares of interstitial keratitis and sudden onset of Ménière-like attacks (nausea, vomiting, tinnitus, vertigo and hearing loss). Life-threatening aortic insufficiency develops in 10% of reported cases. Atypical Cogan's syndrome (audiovestibular dysfunction with other types of inflammatory eye disease) is associated with vasculitis in 20% of cases and has a less favourable prognosis than typical Cogan's syndrome.
authors.affiliation: Clínica Puerta de Hierro, Universidad Autónoma, Madrid, Spain.
authors.forename: J R
authors.initials: JR
authors.lastname: García Berrocal
authors.forename: J A
authors.initials: JA
authors.lastname: Vargas
authors.forename: M
authors.initials: M
authors.lastname: Vaquero
authors.forename: S
authors.initials: S
authors.lastname: Ramón y Cajal
authors.forename: R A
authors.initials: RA
authors.lastname: Ramírez-Camacho
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000188:drug therapy; D003638:Deafness / Q000175:diagnosis* / Q000188:drug therapy; D005128:Eye Diseases / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013577:Syndrome
chemical_list: D000305:Adrenal Cortex Hormones