Clinical and electrophysiologic results after intracameral lidocaine 1% anesthesia: a prospective randomized study.
OBJECTIVE
To evaluate the efficacy and safety of intracameral lidocaine in cataract surgery compared to peribulbar anesthesia.


METHODS
A prospective, randomized, controlled study.


METHODS
A total of 200 consecutive cataract patients (200 eyes) participated.


METHODS
Eyes were randomly assigned to two groups: one group received 0.15 ml intracameral 1% unpreserved lidocaine combined with topical anesthesia (oxybuprocaine); the other group received 6 ml prilocaine peribulbar before phacoemulsification with sclerocorneal tunnel incision.


METHODS
Duration of surgery was measured; implicit time and amplitudes of the b-waves of the photopic electroretinogram (ERG) potentials (single-flash ERG and the 30-Hz flicker ERG) were recorded; frequencies of intraoperative problems, complications, intraoperative, and postoperative pain were evaluated.


RESULTS
After lidocaine anesthesia combined with topical anesthesia, similar complications were found, longer operation time (P < 0.001), and significantly better visual acuity immediately after surgery (P < 0.001). The ERG amplitudes were not significantly reduced after 0.15-ml intracameral lidocaine half an hour after surgery (P > 0.05).


CONCLUSIONS
Intracameral lidocaine 1% combined with topical anesthesia can be recommended as an alternative procedure to peribulbar anesthesia in cataract surgery with corneoscleral tunnel incision.
Anders
N
N
Department of Ophthalmology, Charté, Faculty of Humboldt University, Berlin, Germany. norbert.anders@charite.de
Heuermann
T
T
Rüther
K
K
Hartmann
C
C
D000368:Aged; D000772:Anesthesia, Local / Q000379:methods*; D019162:Anesthetics, Combined / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D004596:Electroretinography; D006801:Humans; D019654:Lens Implantation, Intraocular; D008012:Lidocaine / Q000008:administration & dosage*; D009915:Orbit; D010147:Pain Measurement; D010149:Postoperative Pain; D017060:Patient Satisfaction; D018918:Phacoemulsification; D011343:Procaine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D011446:Prospective Studies; D012160:Retina / Q000187:drug effects / Q000502:physiology; D014792:Visual Acuity
D019162:Anesthetics, Combined; D000779:Anesthetics, Local; D011343:Procaine; D008012:Lidocaine; C005298:benoxinate