[The factors influencing the completeness of skin regeneration in mammals].
In the majority of experimental studies on skin regeneration, which were conducted on the backs of rats and mice, wound healing resulted in the formation of epithelialized scars of the connective tissue. Using various methods to influence the process of skin regeneration in this and other models, we were able to obtain in some cases the organotypic regeneration accompanied by the formation of skin derivatives. We conclude that we have detected factors affecting the extent of posttraumatic skin regeneration in mammals.
Efimov
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EA
Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow, Russia.
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D001345:Autoradiography; D002084:Butylated Hydroxytoluene / Q000494:pharmacology; D002921:Cicatrix / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D018859:Hair Follicle / Q000187:drug effects / Q000502:physiology; D006364:Hedgehogs; D051379:Mice; D011817:Rabbits; D051381:Rats; D012038:Regeneration / Q000187:drug effects / Q000502:physiology*; D012867:Skin / Q000033:anatomy & histology / Q000187:drug effects / Q000293:injuries; D012879:Skin Physiological Phenomena / Q000187:drug effects; D013997:Time Factors
D000975:Antioxidants; D002084:Butylated Hydroxytoluene