title: The effect of buphthalmos on orbital growth in early childhood: increased orbital soft tissue volume strongly correlates with increased orbital volume.
abstract: OBJECTIVE
  Our purpose was to evaluate the effect of increased orbital soft tissue volume on orbital growth.
  
  
  METHODS
  Patients with unilateral or significantly asymmetric bilateral buphthalmos as determined by axial computed tomography scan were recruited. Volumetric determinations of the bony orbit with use of axial 1.5 mm sections on computed tomography were undertaken. Statistical analysis of the paired ocular length measurement and bony orbital volume measurements for each patient were performed.
  
  
  RESULTS
  Eight patients (mean age 41 months) with a 15% or greater difference in axial length were enrolled. The mean axial length of the buphthalmic globes was 23% greater than that of the contralateral globes. Orbits harboring a buphthalmic globe had an orbital volume 11% greater than on the contralateral side.
  
  
  CONCLUSIONS
  Increased orbital soft tissue volume as evidenced by buphthalmos was significantly associated with enlarged bony orbital volume. This indicates that soft tissue volume is a determinant of orbital volume and suggests that orbital tissue expanders might enhance bony development in patients with anophthalmos or microphthalmos and after early enucleation.
authors.affiliation: King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
authors.forename: G W
authors.initials: GW
authors.lastname: Heinz
authors.forename: D A
authors.initials: DA
authors.lastname: Clunie
authors.forename: P B
authors.initials: PB
authors.lastname: Mullaney
mesh_terms: D001846:Bone Development; D002675:Child, Preschool; D005123:Eye / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D006871:Hydrophthalmos / Q000150:complications* / Q000000981:diagnostic imaging; D007223:Infant; D009915:Orbit / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed