title: Long-term effect of large biliary endoprostheses in high-risk surgical patients with irretrievable common bile duct stones.
abstract: BACKGROUND
  Endoscopic sphincterotomy and basket extraction are currently used to remove bile duct stones, with a duct clearance rate of 85% to 90%. A biliary endoprosthesis (stent) is an alternative method to treat difficult cases, especially high-risk surgical patients. The aim of this study was to investigate the long-term effect of biliary endoprostheses in patients with irretrievable common bile duct stones.
  
  
  METHODS
  From December, 1990, to November, 1998, 546 patients were referred to the Veterans General Hospital-Kaohsiung for endoscopic removal of common bile duct stones. Of them, 12 received long-term biliary endoprosthesis because endoscopic removal or surgery was not suitable. Large-caliber stents (> 10 French) were inserted into 12 patients (5 women and 7 men, mean age, 78.4 years) and they were followed up with regular clinical visits. Quantitative cholescintigraphy was performed in four patients to evaluate biliary emptying after liver function returned to normal.
  
  
  RESULTS
  No early complications from stent insertion occurred and a satisfactory resolution of jaundice, pain and fever were noted in all patients. One patient had repeated cholangitis due to stent occlusion and five died from unrelated causes. The median effective period of stent placement was 11 months (range, 1-38 months). Quantitative cholescintigraphy revealed delayed biliary drainage in four patients despite an absence of symptoms after their liver function returned to normal.
  
  
  CONCLUSIONS
  Large-caliber stents are a safe and effective treatment for long-term palliation in high-risk patients with retained common bile duct stones.
authors.affiliation: Department of Internal Medicine, Veterans General Hospital-Kaohsiung, Taiwan, ROC.
authors.forename: M K
authors.initials: MK
authors.lastname: Ku
authors.forename: K H
authors.initials: KH
authors.lastname: Lai
authors.forename: G H
authors.initials: GH
authors.lastname: Lo
authors.forename: J S
authors.initials: JS
authors.lastname: Cheng
authors.forename: P I
authors.initials: PI
authors.lastname: Hsu
authors.forename: C K
authors.initials: CK
authors.lastname: Lin
authors.forename: H H
authors.initials: HH
authors.lastname: Chan
authors.forename: J H
authors.initials: JH
authors.lastname: Hsu
authors.forename: W T
authors.initials: WT
authors.lastname: Lin
authors.forename: E M
authors.initials: EM
authors.lastname: Wang
authors.forename: N J
authors.initials: NJ
authors.lastname: Peng
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D042882:Gallstones / Q000601:surgery*; D006801:Humans; D008297:Male; D011446:Prospective Studies; D016717:Sphincterotomy, Endoscopic; D015607:Stents