title: Macquarimicin A inhibits membrane-bound neutral sphingomyelinase from rat brain.
authors.affiliation: Biomedical Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: F
authors.initials: F
authors.lastname: Nara
authors.forename: Y
authors.initials: Y
authors.lastname: Yamasato
authors.forename: S
authors.initials: S
authors.lastname: Masuda-Inoue
authors.forename: H
authors.initials: H
authors.lastname: Doi-Yoshioka
authors.forename: S
authors.initials: S
authors.lastname: Kumakura
authors.forename: R
authors.initials: R
authors.lastname: Enokita
authors.forename: T
authors.initials: T
authors.lastname: Ogita
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D001409:Bacillus cereus / Q000187:drug effects / Q000201:enzymology; D001921:Brain / Q000187:drug effects / Q000201:enzymology*; D002351:Carrageenan; D015232:Dinoprostone / Q000096:biosynthesis; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D007700:Kinetics; D008070:Lipopolysaccharides / Q000494:pharmacology; D018942:Macrolides; D008847:Micromonospora / Q000378:metabolism; D009000:Monocytes / Q000187:drug effects / Q000378:metabolism; D051381:Rats; D013108:Sphingomyelin Phosphodiesterase / Q000037:antagonists & inhibitors*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000201:enzymology
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004791:Enzyme Inhibitors; D008070:Lipopolysaccharides; D018942:Macrolides; C094822:macquarimicin A; D002351:Carrageenan; D013108:Sphingomyelin Phosphodiesterase; D015232:Dinoprostone