title: Extracranial contribution to cerebral oximetry in brain dead patients: a report of six cases.
abstract: The near infrared spectroscopy offers a noninvasive method to monitor regional brain oxygenation. The problem with the technique appears to be possible extacranial contribution to the measurements. As a part of another study, we monitored regional saturation (rSO2) in six brain dead patients either during the test for spontaneous respiration or in those not eligible for organ donation, after discontinuation of mechanical ventilation. Relatively normal rSO2 values were obtained after brain death, and the values decreased concomitantly with the hemoglobin saturation of oxygen (SpO2) after the discontinuation of mechanical ventilation. A corresponding decrease in SpO2 and rSO2 suggests extracranial contribution to the measured rSO2. The diagnosis of brain death cannot be made based on this technology; furthermore the presence of extracranial contribution may limit its potential value even in other applications.
authors.affiliation: Department of Anesthesia, Töölö Hospital, Helsinki, Finland.
authors.forename: J
authors.initials: J
authors.lastname: Kyttä
authors.forename: J
authors.initials: J
authors.lastname: Ohman
authors.forename: P
authors.initials: P
authors.lastname: Tanskanen
authors.forename: T
authors.initials: T
authors.lastname: Randell
mesh_terms: D000328:Adult; D001926:Brain Death / Q000097:blood / Q000503:physiopathology*; D001930:Brain Injuries; D002560:Cerebrovascular Circulation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010092:Oximetry / Q000379:methods; D010100:Oxygen / Q000097:blood*; D013345:Subarachnoid Hemorrhage
chemical_list: D010100:Oxygen