title: [Usefulness of visualized highly sensitive new chemical dosimeter: application to blood irradiation].
abstract: In the prophylaxis of post-transfusion GVHD, it is recommended to irradiate blood components with an absorbed dose ranging from 15 Gy to 50 Gy. We applied a new chemical dosimeter to measure absorbed dose for blood irradiation. This system is composed of diphenyliodoniumchloride (DICI) as an oxidizer and crystal violet lactone as a pH indicator. Protons are released from DICI after irradiation. The maximum absorption wavelength of this indicator is 610 nm, and absorbance is linearly related with a given dose from 1 to 50 Gy. Coloration is stable for at least 2 weeks when stored in the dark at 4 degrees C. This system may be used as a chemical dosimeter for blood irradiation.
authors.affiliation: Department of Radiology, Jikei University School of Medicine.
authors.forename: H
authors.initials: H
authors.lastname: Sekine
authors.forename: M
authors.initials: M
authors.lastname: Takiue
authors.forename: Y
authors.initials: Y
authors.lastname: Yoshizawa
authors.forename: T
authors.initials: T
authors.lastname: Natake
authors.forename: C
authors.initials: C
authors.lastname: Kanehira
mesh_terms: D001769:Blood / Q000528:radiation effects*; D001803:Blood Transfusion; D005720:Gamma Rays; D006086:Graft vs Host Disease / Q000517:prevention & control*; D006801:Humans; D011874:Radiometry; D012680:Sensitivity and Specificity