The relationship between pityriasis rubra pilaris and inflammatory arthritis: case report and response of the arthritis to anti-tumor necrosis factor immunotherapy.
Pityriasis rubra pilaris (PRP) refers to a group of erythematous, scaling dermatologic conditions that have been associated with seronegative arthritis. We report a case of polyarthritis in a young man with PRP in which magnetic resonance imaging suggested an entheseal-based pathology for the joint disease. The arthritis, but not the skin condition, demonstrated dramatic response to anti-tumor necrosis factor immunotherapy.
Conaghan
P G
PG
University of Leeds, UK.
Sommer
S
S
McGonagle
D
D
Veale
D
D
Waldmann
H
H
Hale
G
G
Goodfield
M
M
Emery
P
P
Isaacs
J
J
D000293:Adolescent; D000906:Antibodies / Q000627:therapeutic use; D001168:Arthritis / Q000150:complications* / Q000628:therapy; D016860:CD4 Immunoadhesins / Q000627:therapeutic use; D006801:Humans; D007167:Immunotherapy; D008297:Male; D010916:Pityriasis Rubra Pilaris / Q000150:complications*; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology
D000906:Antibodies; D016860:CD4 Immunoadhesins; D014409:Tumor Necrosis Factor-alpha