[The mechanisms of the anti-ulcer action of plant drug agents].
The mechanisms of the gastroprotective effect of well-known drugs (plantaglucid, befungin, plantain juice), extractions of birch bark (Betula pendula Roth,) and burdock seeds (Arctium tomentosum Mill.) on various links of gastric ulcer pathogenesis were compared. Phytopreparations were found to have a variety of effects on gastric secretion in rats. Differences in their action on the smooth muscles of the stomach and intestine were detected.
Os'kina
O A
OA
Institute of Pharmacology, Siberian Branch of Russian Academy of Medical Sciences, Tomsk, Russia.
Pashinskiĭ
V G
VG
Kanakina
T A
TA
Povet'eva
T N
TN
Gribel'
N V
NV
D000818:Animals; D000897:Anti-Ulcer Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001241:Aspirin; D004353:Drug Evaluation, Preclinical; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism; D005769:Gastrointestinal Motility / Q000187:drug effects; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D017208:Rats, Wistar; D018709:Statistics, Nonparametric; D013276:Stomach Ulcer / Q000139:chemically induced / Q000188:drug therapy* / Q000503:physiopathology
D000897:Anti-Ulcer Agents; D010936:Plant Extracts; D001241:Aspirin