title: [Genetic demographic characteristics of the rural population of the Tuva Republic: marriage structure and inbreeding].
abstract: Marriage structure was studied in three rural populations of the Tuva Republic: the Shinaan population and the populations of Todzhinskii and Bai-Taiginskii raions (districts). The Shinaan and Bai-Taiginskii populations had high levels of endogamy (0.6704 and 0.6050, respectively). In the Todzhinskii population, which was characterized by a mixed ethnic composition, endogamy was 0.3779 for the total population and 0.4626 for Tuvinians; interethnic marriages in this population were rare. The values of marriage assortativeness with respect to birthplace were 19.38, 40.75, 75.87, and 41.87% in the Shinaan, Bai-Taiginskii, all the Todzhinskii populations, and Tuvinian monoethnic marriages in the Todzhinskii raion, respectively. High marriage assortativeness with respect to ethnicity was found. Its values (A') were 91.85 and 93.49% in Tuvinians and Russians, respectively. Tuvinian populations were characterized by high inbreeding. The total (F(it)), random (Fst), and nonrandom inbreeding (Fis) estimated by isonymy were 0.004237, 0.002298, and 0.001944 in the Shinaan population, 0.007292, 0.009448, and -0.002177 in the Bai-Taiginskii population, and 0.003846, 0.004152, and -0.000307 in the Todzhinskii population, respectively (in the latter populations, the F(it), Fst, and Fis values for Tuvinian marriages alone were 0.005000, 0.007222, and -0.002238, respectively). The results obtained indicate that individual territorial groups of Tuvinians retain a high degree of genetic isolation from one another.
authors.affiliation: Institute of Medical Genetics, Tomsk Research Center, Russian Academy of Medical Sciences, Russia. aksana@img.tsu.ru
authors.forename: A N
authors.initials: AN
authors.lastname: Kucher
authors.forename: V P
authors.initials: VP
authors.lastname: Puzyrev
authors.forename: N O
authors.initials: NO
authors.lastname: Sanchat
authors.forename: L S
authors.initials: LS
authors.lastname: Erdynieva
mesh_terms: D000328:Adult; D003241:Consanguinity; D003710:Demography; D005006:Ethnicity; D005260:Female; D005828:Genetics, Population; D006801:Humans; D008297:Male; D008393:Marriage; D012424:Rural Population; D012426:Russia