Elective transfer of embryos selected on the basis of first polar body morphology is associated with increased rates of implantation and pregnancy.
OBJECTIVE
To determine the relationship between first polar body morphology and implantation rate and pregnancy rate (PR), to facilitate decision making concerning elective ET.


METHODS
Prospective, randomized study.


METHODS
Fertility center.


METHODS
One hundred fifty-eight consecutive patients (173 intracytoplasmic sperm injection cycles) resulting in embryo transfers.


METHODS
In our study group, priority in ET was given to embryos derived from well-shaped first polar bodies, whereas selection of embryos for transfer in the control group was based exclusively on the degree of embryo fragmentation.


METHODS
Total numbers of implantations and pregnancies, PR and implantation rate, and rates of multiple pregnancy and miscarriage.


RESULTS
In the study cohort, 212 embryos were transferred. In the control group, 313 embryos were transferred. The implantation rate and PR were significantly lower in the control group than in the study cohort. In addition, the rate of multiple pregnancy was significantly higher in the study group.


CONCLUSIONS
Elective transfer of embryos selected on the basis of first polar body morphology results in higher implantation and pregnancy rates. Multiple pregnancy can be avoided by transferring a reduced number of embryos selected on the basis of first polar body morphology.
Ebner
T
T
In Vitro Fertilization Unit, Women's General Hospital, Linz, Austria. frauenklinik.linz@li.lkh.ooe.gv.at
Moser
M
M
Yaman
C
C
Feichtinger
O
O
Hartl
J
J
Tews
G
G
D000328:Adult; D015331:Cohort Studies; D010064:Embryo Implantation; D004624:Embryo Transfer; D004622:Embryo, Mammalian / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D018873:Pregnancy Rate; D011272:Pregnancy, Multiple; D011446:Prospective Studies; D020554:Sperm Injections, Intracytoplasmic