title: Enantioselective Total Synthesis of Avarol and Avarone.
abstract: Formation of the C11-C1' bond through application of Barton's radical decarboxylation and quinone addition is the cornerstone of a new convergent and concise synthesis of the marine metabolites avarol (1) and avarone (2; see scheme), for which antimitotic, antileukemic, and antiviral effects have been reported.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive #0358, La Jolla, CA 92093-0358 (USA).
authors.initials: T
authors.lastname: Ling
authors.initials: AX
authors.lastname: Xiang
authors.initials: EA
authors.lastname: Theodorakis