Melkersson-Rosenthal syndrome in childhood: successful management with combination steroid and minocycline therapy.
The Melkersson-Rosenthal syndrome consists of a triad of recurrent lip and/or face swelling, fissured tongue, and intermittent facial palsy. Onset of the symptoms may occur during childhood, and treatment of the condition is difficult. We describe two children with Melkersson-Rosenthal syndrome in whom combination treatment with prednisone and minocycline proved effective and well tolerated.
Stein
S L
SL
Department of Dermatology, Northwestern University Medical School, Children's Memorial Hospital, Chicago, Illinois, USA.
Mancini
A J
AJ
D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008556:Melkersson-Rosenthal Syndrome / Q000188:drug therapy*; D008911:Minocycline / Q000627:therapeutic use*; D011241:Prednisone / Q000627:therapeutic use*
D005938:Glucocorticoids; D008911:Minocycline; D011241:Prednisone