Xpitx-1: a homeobox gene expressed during pituitary and cement gland formation of Xenopus embryos.
Pitx-1 is a member of the family of bicoid-related vertebrate homeobox genes; it was originally identified as a tissue-specific transcriptional regulator of the proopiomelacortin gene. Here we report on the embryonic expression of Xpitx-1, which is expressed in the anterior neural ridge and in the cement gland Anlage during late gastrulation/early neurulation. In tadpole stage embryos Xpitx-1 transcripts are primarily detected in the cement gland, stomodeal-hypophyseal Anlage, oral epithelia and lens placode. Therefore, Xpitx-1 may be part of the genetic network that controls the early development of these structures.
Hollemann
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Georg-August-Universität Göttingen, Institute of Biochemistry and Molecular Cell Biology, Humboldtallee 23, D-37073, Göttingen, Germany. thollem1@gwdg.de
Pieler
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D000595:Amino Acid Sequence; D000818:Animals; D003001:Cloning, Molecular; D004475:Ectoderm / Q000378:metabolism; D004625:Embryo, Nonmammalian; D005088:Exocrine Glands / Q000196:embryology*; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D051761:Paired Box Transcription Factors; D010902:Pituitary Gland / Q000196:embryology*; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism; D014982:Xenopus laevis / Q000196:embryology* / Q000235:genetics
D018398:Homeodomain Proteins; D051761:Paired Box Transcription Factors; D014157:Transcription Factors; C101485:homeobox protein PITX1