[The effect of immobilized salivary alkaline phosphatase on remineralization processes].
Relationship between alkaline phosphatase immobilized on apatite and remineralization processes has been studied. The enzyme notably accelerated the remineralization. The course of enzymatic remineralization depended on the source of phosphorus (inorganic phosphorus or beta-glycerophosphate). Calcium incorporation in remineralizing surface was the most rapid in the presence of beta-glycerophosphate. This may be explained by a higher rate of formation of apatite under the effect of immobilized alkaline phosphatase, than of brushite or vitlokite.
Zhitkov
M Iu
MIu
D000469:Alkaline Phosphatase / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D001031:Apatites; D003743:Dental Enamel / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004800:Enzymes, Immobilized / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D007978:Levamisole / Q000494:pharmacology; D012463:Saliva / Q000201:enzymology*; D012996:Solutions; D014074:Tooth Calcification / Q000187:drug effects*; D014089:Tooth Remineralization / Q000379:methods
D001031:Apatites; D004791:Enzyme Inhibitors; D004800:Enzymes, Immobilized; D012996:Solutions; D007978:Levamisole; D000469:Alkaline Phosphatase