Wound healing: new understandings.
Understanding wound healing has moved from the cellular to the molecular level. In the clinical arena, however, care is often based on evaluation of the external manifestations of the wound, whereas treatments emanate primarily from tradition. Advances in knowledge make it necessary to understand healing at multiple levels to provide sound treatments. This article expands several molecular explanations for altered healing and suggests treatments aimed at restoring chronic wounds to a milieu for repair.
Cooper
D M
DM
Ortho-McNeil Pharmaceutical, Inc, Raritan, NJ 08869-0602, USA.
D000208:Acute Disease; D002908:Chronic Disease; D003646:Debridement; D006097:Granulation Tissue / Q000502:physiology; D006133:Growth Substances / Q000502:physiology / Q000627:therapeutic use; D006801:Humans; D007249:Inflammation; D008967:Molecular Biology; D014945:Wound Healing / Q000502:physiology*; D014947:Wounds and Injuries / Q000503:physiopathology* / Q000628:therapy
D006133:Growth Substances