Development of clinical methods of iron deprivation for suppression of neoplastic and infectious diseases.
Hosts attempt to withhold growth-essential iron from neoplastic and microbial cells. This review focuses on the development of medical and pharmaceutical methods designed to enhance the iron-withholding defense system.
Weinberg
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ED
Department of Biology, Indiana University, Bloomington, USA. eweinber@indiana.edu
D000818:Animals; D006801:Humans; D007239:Infections / Q000188:drug therapy / Q000378:metabolism* / Q000628:therapy*; D007501:Iron / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D007502:Iron Chelating Agents / Q000627:therapeutic use*; D009369:Neoplasms / Q000378:metabolism* / Q000517:prevention & control / Q000628:therapy*
D007502:Iron Chelating Agents; D007501:Iron