Keloids and hypertrophic scars: results with intraoperative and serial postoperative corticosteroid injection therapy.
BACKGROUND
The management of keloids and hypertrophic scars continues to be controversial. Experience of treating 58 such lesions, 58.62% of which were recurrent, is presented.


METHODS
Each lesion was subjected to surgical excision with intra-operative local injection of triamcinolone acetonide, followed by repeat injection of the same drug at weekly intervals for 2-5 weeks depending on the symptomatic relief, and then monthly injections for 4-6 months.


RESULTS
Complete symptomatic relief was achieved in all patients within 5 weeks of surgery. Objective response in terms of no recurrence was noted in 91.9% of patients with keloids, and 95.24% of patients with hypertrophic scars at a mean follow-up of 30.5 months. Local or systemic complications were insignificant.


CONCLUSIONS
Because of promising results, further use and evaluation of this method of treatment is recommended for large, recurrent and complicated keloids and hypertrophic scars.
Chowdri
N A
NA
Department of Plastic and Reconstructive Surgery, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar (J&K), India.
Masarat
M
M
Mattoo
A
A
Darzi
M A
MA
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D017439:Cicatrix, Hypertrophic / Q000188:drug therapy* / Q000601:surgery; D004334:Drug Administration Schedule; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D007267:Injections; D007430:Intraoperative Care; D007627:Keloid / Q000188:drug therapy* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D014222:Triamcinolone Acetonide