title: Multiple red blood cell antibodies produced by donor B lymphocytes after ABO-matched allogeneic bone marrow transplantation.
abstract: A 50-year-old man with AML[M2,t(8;21)] underwent BMT from his younger sister. At that time, he had no unexpected antibody and his blood type was O(+), CcDEe. The type of Kidd was not examined. The donor's blood type was O(+), CCDee, Jk(a+b-). One year after the BMT, the patient's blood type had changed to that of the donor's and anti-E antibody was detected. Despite the use of platelet concentrates (PCs) only, anti-c antibody was later identified. We conclude that there is a need to check red cell antibodies at regular intervals, even when using PCs only, for earlier detection of unexpected antibodies after BMT.
authors.affiliation: Department of Clinical Pathology, Iwate Medical University, Japan. ttasaki@cap.iwate-med.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Tasaki
authors.forename: S
authors.initials: S
authors.lastname: Sasaki
authors.forename: K
authors.initials: K
authors.lastname: Gotoh
authors.forename: C
authors.initials: C
authors.lastname: Itoh
authors.forename: S
authors.initials: S
authors.lastname: Itoh
authors.forename: S
authors.initials: S
authors.lastname: Kuriya
mesh_terms: D000017:ABO Blood-Group System / Q000276:immunology*; D000917:Antibody Formation; D001402:B-Lymphocytes / Q000378:metabolism*; D016026:Bone Marrow Transplantation / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000276:immunology / Q000628:therapy; D008297:Male; D008875:Middle Aged
chemical_list: D000017:ABO Blood-Group System