title: [Mucosal morphology in the latent form of terminal ileitis in children based on biopsy data].
abstract: Morphological study of serial section biopsies from 22 children was made to develop new diagnostic criteria of a latent form of terminal ileitis. The following changes were observed: fibroblastic reaction around the lymphoid follicles, degenerative changes of enterocytes close to the lymphoid follicles; disruption of basal membrane over the lymphoid follicles; penetration of lymphoid cells into the intestinal lumen and their adhesion to the apical membrane of enterocytes; neuroma-like structures as an issue of productive vasculitis. The frequency of the symptoms above 62% does not depend on the sex, age and treatment method.
authors.affiliation: Research Institute of Pediatric Gastroenterology, Nizhny Novgorod.
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Fadeev
authors.forename: V P
authors.initials: VP
authors.lastname: Smirnov
mesh_terms: D000293:Adolescent; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003093:Colitis, Ulcerative / Q000473:pathology; D003424:Crohn Disease / Q000473:pathology; D005260:Female; D006801:Humans; D007079:Ileitis / Q000473:pathology*; D007082:Ileum / Q000473:pathology*; D007413:Intestinal Mucosa / Q000473:pathology*; D008297:Male; D012189:Retrospective Studies