Surface EMG of proximal leg muscles in neuromuscular patients and in healthy controls. Relations to force and fatigue.
In an effort to find parameters to evaluate patients with neuromuscular disorders, surface electromyography (SEMG) of proximal leg muscles was performed in 33 patients with myotonic dystrophy (MyD), 29 patients with Charcot-Marie-Tooth (CMT) disease and 20 healthy controls. The root mean square (RMS) of the SEMG amplitude (microV) was calculated at different torque levels. Endurance (seconds) and median frequency (Fmed) of the SEMG power spectrum, used as parameters of fatigue, were determined at 80% of MVC. Maximum voluntary contraction (MVC) was found to be decreased in patients; the ratio between RMS values of antagonists and agonists was increased and torque-EMG ratios (Nm/microV) were decreased. These differences with respect to controls were more pronounced in MyD than in CMT. The initial Fmed value was lowest in CMT. The greatest decrease in Fmed was found in MyD. SEMG data in relation to force have not been determined before in groups of MyD or CMT patients. In both disorders, parameters differed from controls, which means that adding SEMG to strength measurements could be useful in studying the progress of the disorder and the effects of interventions.
Lindeman
E
E
Department of Rehabilitation, University Hospital, Maastricht, Netherlands. e.lindman@pmbr.azu.nl
Spaans
F
F
Reulen
J P
JP
Leffers
P
P
Drukker
J
J
D000328:Adult; D002607:Charcot-Marie-Tooth Disease / Q000503:physiopathology*; D018450:Disease Progression; D004576:Electromyography; D005260:Female; D006801:Humans; D007866:Leg; D008297:Male; D009119:Muscle Contraction; D018763:Muscle Fatigue / Q000502:physiology; D018482:Muscle, Skeletal / Q000503:physiopathology*; D009223:Myotonic Dystrophy / Q000503:physiopathology*; D010807:Physical Endurance