Selective ablation of porcine and rabbit liver tissue using radiofrequency: preclinical study.
Temperature changes and their distribution induced by 13.56-MHz radiofrequency (RF) heating of agar phantom and porcine and rabbit liver were investigated. It was possible to produce selective local heating of approximately 50 degrees C in the RF field of 2 x 2 x 2 cm(3) of the pig or rabbit liver. Coagulation necrosis after heating became pronounced and the margin between the coagulated lesion and normal tissue became clearer with time. Within 1 week after RF heating at 50 degrees C for 20 min, the coagulated area was replaced selectively and totally by necrotic tissue.
Nakagawa
A
A
First Department of Surgery, Kansai Medical University, Osaka, Japan.
Kamiyama
Y
Y
Matsui
Y
Y
Nakagawa
M
M
Araki
H
H
Kasamatsu
S
S
Wei
T
T
Okuda
Y
Y
Kitade
H
H
Kamiya
T
T
Noro
T
T
Kubo
N
N
Nakase
Y
Y
D000818:Animals; D017115:Catheter Ablation; D006358:Hot Temperature; D008099:Liver / Q000473:pathology / Q000601:surgery*; D009336:Necrosis; D019047:Phantoms, Imaging; D011817:Rabbits; D013552:Swine; D013696:Temperature