title: Effect of some herbicides on the production of lysine by Azotobacter chroococcum.
abstract: Production of lysine by Azotobacter chroococcum strain H23 was studied in chemically-defined media amended with different concentrations of alachlor, metolachlor, 2,4-D, 2,4,5-T and 2,3,6-TBA. The presence of 5, 10, and 50 micrograms/ml of alachlor or 2,3,6-TBA significantly decreased quantitative production of lysine. However, the presence 2,4-D or 2,4,5-T at concentrations of 10 and 50 micrograms/ml enhanced the production of lysine. Quantitative production of lysine was not affected as consequence of the addition of metolachlor to the culture medium, showing that the release lysine to the culture media by A. chroococcum was not affected by that herbicide.
authors.affiliation: Department of Microbiology, Faculty of Pharmacy, University of Granada, Spain.
authors.forename: J
authors.initials: J
authors.lastname: González-López
authors.forename: M V
authors.initials: MV
authors.lastname: Martínez-Toledo
authors.forename: B
authors.initials: B
authors.lastname: Rodelas
authors.forename: V
authors.initials: V
authors.lastname: Salmerón
mesh_terms: D015085:2,4,5-Trichlorophenoxyacetic Acid / Q000494:pharmacology; D015084:2,4-Dichlorophenoxyacetic Acid / Q000494:pharmacology; D000081:Acetamides / Q000494:pharmacology; D000596:Amino Acids / Q000096:biosynthesis; D001395:Azotobacter / Q000187:drug effects* / Q000378:metabolism*; D001565:Benzoates / Q000494:pharmacology*; D002723:Chlorobenzoates; D004305:Dose-Response Relationship, Drug; D006540:Herbicides / Q000494:pharmacology*; D008239:Lysine / Q000096:biosynthesis*; D013858:Thiobarbiturates / Q000494:pharmacology; D013997:Time Factors
chemical_list: D000081:Acetamides; D000596:Amino Acids; D001565:Benzoates; D002723:Chlorobenzoates; D006540:Herbicides; D013858:Thiobarbiturates; C000188:alachlor; D015084:2,4-Dichlorophenoxyacetic Acid; C401701:2,3,6-trichlorobenzoic acid; D015085:2,4,5-Trichlorophenoxyacetic Acid; D008239:Lysine; C029684:thiobarbituric acid; C051786:metolachlor