title: The promise of comparative genomics in mammals.
abstract: Dense genetic maps of human, mouse, and rat genomes that are based on coding genes and on microsatellite and single-nucleotide polymorphism markers have been complemented by precise gene homolog alignment with moderate-resolution maps of livestock, companion animals, and additional mammal species. Comparative genetic assessment expands the utility of these maps in gene discovery, in functional genomics, and in tracking the evolutionary forces that sculpted the genome organization of modern mammalian species.
authors.affiliation: Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702-1201, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: O'Brien
authors.forename: M
authors.initials: M
authors.lastname: Menotti-Raymond
authors.forename: W J
authors.initials: WJ
authors.lastname: Murphy
authors.forename: W G
authors.initials: WG
authors.lastname: Nash
authors.forename: J
authors.initials: J
authors.lastname: Wienberg
authors.forename: R
authors.initials: R
authors.lastname: Stanyon
authors.forename: N G
authors.initials: NG
authors.lastname: Copeland
authors.forename: N A
authors.initials: NA
authors.lastname: Jenkins
authors.forename: J E
authors.initials: JE
authors.lastname: Womack
authors.forename: J A
authors.initials: JA
authors.lastname: Marshall Graves
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000235:genetics; D001483:Base Sequence; D002874:Chromosome Mapping; D019143:Evolution, Molecular; D005819:Genetic Markers; D016678:Genome; D015894:Genome, Human; D006801:Humans; D008322:Mammals / Q000235:genetics*; D009154:Mutation; D010802:Phylogeny; D012377:Rodentia / Q000235:genetics
chemical_list: D005819:Genetic Markers