Congenital subependymal giant-cell astrocytoma: case report with prenatal ultrasonogram.
BACKGROUND
A prenatal sonogram at 27 weeks of gestation revealed a brain mass along the frontal horn and body of the lateral ventricle near the foramen of Monro in the fetus.


METHODS
A huge subependymal giant-cell astrocytoma was nearly totally resected at 11 days of age.


RESULTS
There was no syndromic family history, but features substantiating the diagnosis of tuberous sclerosis were recognized at 4 years of age.


CONCLUSIONS
The sonographic finding of a tumor in the region of the foramen of Monro should raise the suspicion of a subependymal giant-cell astrocytoma, a tumor characteristically associated with tuberous sclerosis.
Mirkin
L D
LD
Departments of Pathology and Pediatrics, Wright State University School of Medicine, Division of Pathology and Clinical Laboratory, One Children's Plaza, Dayton, OH 45404-1815, USA.
Ey
E H
EH
Chaparro
M
M
D001254:Astrocytoma / Q000151:congenital* / Q000000981:diagnostic imaging* / Q000473:pathology; D001932:Brain Neoplasms / Q000151:congenital* / Q000000981:diagnostic imaging* / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D016216:Ultrasonography, Prenatal