title: A case of sporadic Pick disease with onset at 27 years.
abstract: BACKGROUND
  Pick disease is an uncommon cause of dementia in middle age, and young-onset cases have rarely been reported.
  
  
  METHODS
  A specialist hospital.
  
  
  METHODS
  Patient with onset of cognitive impairment at the age of 27 years whose cerebral biopsy specimen demonstrated Pick cells and tau-positive Pick bodies.
  
  
  CONCLUSIONS
  Pick disease should be considered in the differential diagnosis of dementia in young adults.
authors.affiliation: Institute of Neurology and the National Hospital for Neurology and Neurosurgery, London, England.
authors.forename: J
authors.initials: J
authors.lastname: Jacob
authors.forename: T
authors.initials: T
authors.lastname: Revesz
authors.forename: M
authors.initials: M
authors.lastname: Thom
authors.forename: M N
authors.initials: MN
authors.lastname: Rossor
mesh_terms: D000328:Adult; D017668:Age of Onset; D001284:Atrophy; D003593:Cytoplasm / Q000473:pathology; D003704:Dementia / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009474:Neurons / Q000473:pathology; D020774:Pick Disease of the Brain / Q000473:pathology*