Mortality risk in patients with coronary artery disease and depression.
Investigators at Duke University Medical Center studied the impact of depression on long-term mortality risk in patients with significant coronary artery disease (CAD), defined as > or = 75% narrowing of > or = 1 coronary artery. Participants were classified after testing into nondepressed, mildly depressed and moderately to severely depressed groups. From 5-10 years after the first cardiac catheterization, the mortality ratios were progressively high for the more depressed cohort.
Pokorski
R J
RJ
Worldwide Medical Research and Development, General and Cologne Life, Stamford, CT 06905, USA. pokorski@colognere.com
D000206:Actuarial Analysis; D003327:Coronary Disease / Q000150:complications* / Q000401:mortality*; D003863:Depression / Q000150:complications*; D003866:Depressive Disorder / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D014481:United States / Q000453:epidemiology