A 5-year clinical evaluation of Norplant implants in Senegal.
The principal objective of this 5-year clinical study of Norplant implants was to introduce these implants into the family planning program in Senegal and to determine their overall acceptability and safety in Senegalese acceptors. A total of 300 subjects were enrolled into the trial from August 1986 to July 1991. All the women were followed-up for 5 years or until the implants were removed. The pooled cumulative discontinuation rate was 40.8 +/- 2.91 per 100 women resulting in a continuation rate of 59.2 +/- 2.91 per 100 women. Thirteen subjects (4.3%) were lost during the follow-up. Seven pregnancies were reported throughout the 5 years leading to a cumulative pregnancy rate of 3.3 +/- 1.25 per 100 women. Menstrual problems were the reason most often given for early removal during the first 2 years. After year 2, desire for another pregnancy was the main reason for implant removal. The results presented in this study show that the Norplant implant system is a safe, effective, and acceptable method that meets the needs of the Senegalese family planning program.
Ba
M G
MG
Gynecology and Obstetrics Clinic, University Teaching Hospital Le Dantec, Dakar, Senegal.
Moreau
J C
JC
Sokal
D
D
Dunson
R
R
Dao
B
B
Kouedou
D
D
Diadhiou
F
F
D000328:Adult; D003271:Contraceptive Agents, Female / Q000008:administration & dosage* / Q000009:adverse effects; D004343:Drug Implants; D005260:Female; D006801:Humans; D016912:Levonorgestrel / Q000008:administration & dosage* / Q000009:adverse effects; D008599:Menstruation Disturbances / Q000139:chemically induced; D017060:Patient Satisfaction; D011247:Pregnancy; D011446:Prospective Studies; D012675:Senegal
D003271:Contraceptive Agents, Female; D004343:Drug Implants; D016912:Levonorgestrel