title: Primary progressive aphasia presenting as conduction aphasia.
abstract: We report a case of a woman with primary progressive aphasia (PPA) who presented with conduction aphasia. A 60-year-old, right-handed, Japanese female suffering from progressive aphasia had difficulty in repeating words and phrases. She displayed phonemic paraphasias but had preserved comprehension and had no cognitive or behavior disorder for more than 6 years after the onset of the condition. She was able to continue to work successfully and to perform all her normal daily activities. T1-weighted magnetic resonance imaging revealed minute dilatation of the left inferior horn and sulci in the left hemisphere, and positron emission tomography revealed mild hypometabolism in the left supramarginal gyrus and its surrounding areas. Therefore, she was diagnosed as suffering from PPA presenting as conduction aphasia. We believe that the progressive conduction aphasia of the patient belongs to one of the fluent forms of PPA, and the ability to continue normal work along with the clinical portrayal of preserved memory and cognition skills may be features of a form of PPA presenting as conduction aphasia.
authors.affiliation: Department of Rehabilitation Medicine, University of Occupational and Environmental Health Japan, 1-1 Iseigaoka, Yahatanishi, Kitakyushu, Japan. kenhachi@med.uoeh-u.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Hachisuka
authors.forename: M
authors.initials: M
authors.lastname: Uchida
authors.forename: Y
authors.initials: Y
authors.lastname: Nozaki
authors.forename: S
authors.initials: S
authors.lastname: Hashiguchi
authors.forename: M
authors.initials: M
authors.lastname: Sasaki
mesh_terms: D018886:Aphasia, Conduction / Q000150:complications / Q000209:etiology*; D018888:Aphasia, Primary Progressive / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D014055:Tomography, Emission-Computed