title: Development of a predictive statistical model for the analgesic activity of a family of imides.
abstract: Quantitative structure-activity relationship (QSAR) studies were done with a family of cyclic imides. Promising efforts to create a QSAR model with substantial predictive power for the design of novel cyclic imides with improved analgesic activity are reported.
authors.affiliation: Departamento de Química, Universidade Federal de Santa Catarina (UFSC), Florianópolis, Brazil.
authors.forename: A D
authors.initials: AD
authors.lastname: Andricopulo
authors.forename: R A
authors.initials: RA
authors.lastname: Yunes
authors.forename: V
authors.initials: V
authors.lastname: Cechinel Filho
authors.forename: R J
authors.initials: RJ
authors.lastname: Nunes
authors.forename: J W
authors.initials: JW
authors.lastname: Frazer
authors.forename: E H
authors.initials: EH
authors.lastname: Cordes
mesh_terms: D000700:Analgesics / Q000737:chemistry* / Q000494:pharmacology*; D007094:Imides / Q000737:chemistry* / Q000494:pharmacology*; D015233:Models, Statistical; D008962:Models, Theoretical; D013329:Structure-Activity Relationship
chemical_list: D000700:Analgesics; D007094:Imides