Inhibitory monoclonal antibodies to human cytochrome P450 enzymes: a new avenue for drug discovery.
Gelboin
H V
HV
Laboratory of Molecular Carcinogenesis, National Institute of Health, National Cancer Institute, Building 37, Room 3E24, 37 Convent Drive, Bethesda, MD 20892, USA. GELBOINH@intra.nci.nih.gov
Krausz
K W
KW
Gonzalez
F J
FJ
Yang
T J
TJ
D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors / Q000096:biosynthesis
D000911:Antibodies, Monoclonal; D065607:Cytochrome P-450 Enzyme Inhibitors; D004791:Enzyme Inhibitors; D007527:Isoenzymes; D003577:Cytochrome P-450 Enzyme System