title: [Effect of superphonoelectrophoresis on chorioretinal dystrophy].
abstract: The effect of a pharmacophysical method superphonophoresis on the course of chorioretinal dystrophy has been studied in 320 patients (640 eyes) with chorioretinal dystrophies treated by an ultrasonic UZT-104 device and a Nion galvanic device. The "superexposure" was phonophoresis of a bipolar drug 10% dimethylsulfoxide, creating the optimal conditions for penetration of the main agent through tissue barrier. The results (improvement of visual acuity, hemodynamics, trophics, shown by a higher linear rate of the blood flow in the orbital artery and middle cerebral arteries) persisted for up to 12 months, moreover, the rate of cellular and tissue metabolism increased (the time of adaptation to darkness decreased and color sensitivity increased).
authors.forename: E P
authors.initials: EP
authors.lastname: Gvarishvili
authors.forename: N V
authors.initials: NV
authors.lastname: Dushin
mesh_terms: D000221:Adaptation, Ocular / Q000187:drug effects; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000975:Antioxidants / Q000008:administration & dosage*; D001783:Blood Flow Velocity / Q000187:drug effects; D002829:Choroid / Q000098:blood supply; D015862:Choroid Diseases / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D004359:Drug Therapy, Combination; D006801:Humans; D007478:Iontophoresis; D008875:Middle Aged; D015612:Phonophoresis; D012162:Retinal Degeneration / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000008:administration & dosage*; D014792:Visual Acuity / Q000187:drug effects
chemical_list: D000975:Antioxidants; D014665:Vasodilator Agents