title: Candidate gene markers associated with somatotropic axis and milk selection.
abstract: One of the obstacles to progress in dairy cattle selection is that milk production traits are only expressed after the first calving. However, the use of the quantitative trait loci (QTL) technology will improve the efficiency of dairy industry with a positive image for the consumers. QTL are part of the genome showing a preponderant action and explaining the major part of variation of the trait production. At the present time, the two major strategies developed to detect such QTL are the candidate gene approach and the positional genetics approach. The somatotropic axis contains the most promising candidates in this respect, as it strongly regulates milk production. Then, the identification of favorable QTL associated with the somatotropic axis that are significantly correlated with genetic merits for milk production could lead to more effective selection programs.
authors.affiliation: Biology and Biochemistry Applied Department, Gembloux Agricultural University, Belgium.
authors.forename: I
authors.initials: I
authors.lastname: Parmentier
authors.forename: D
authors.initials: D
authors.lastname: Portetelle
authors.forename: N
authors.initials: N
authors.lastname: Gengler
authors.forename: A
authors.initials: A
authors.lastname: Prandi
authors.forename: C
authors.initials: C
authors.lastname: Bertozzi
authors.forename: L
authors.initials: L
authors.lastname: Vleurick
authors.forename: R
authors.initials: R
authors.lastname: Gilson
authors.forename: R
authors.initials: R
authors.lastname: Renaville
mesh_terms: D000818:Animals; D002417:Cattle / Q000235:genetics* / Q000502:physiology; D004268:DNA-Binding Proteins / Q000235:genetics / Q000502:physiology; D005260:Female; D005786:Gene Expression Regulation; D005819:Genetic Markers / Q000502:physiology; D013006:Growth Hormone / Q000097:blood / Q000235:genetics / Q000502:physiology*; D013007:Growth Hormone-Releasing Hormone / Q000235:genetics / Q000502:physiology; D007334:Insulin-Like Growth Factor I / Q000235:genetics / Q000502:physiology; D007774:Lactation; D008297:Male; D008892:Milk / Q000378:metabolism*; D011110:Polymorphism, Genetic / Q000235:genetics; D019655:Quantitative Trait, Heritable; D017526:Receptor, IGF Type 1 / Q000235:genetics / Q000502:physiology; D011986:Receptors, Somatotropin / Q000235:genetics / Q000502:physiology; D050817:Transcription Factor Pit-1; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology
chemical_list: D004268:DNA-Binding Proteins; D005819:Genetic Markers; D011986:Receptors, Somatotropin; D050817:Transcription Factor Pit-1; D014157:Transcription Factors; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone; D017526:Receptor, IGF Type 1