Comparison of outcomes research with clinical trials using preexisting data.
Outcomes research using analysis of preexisting data is a relatively new field with the potential to improve the quality and effectiveness of medical care, and may provide a useful complement to randomized studies. Motivated by the growth of this research in the cardiovascular literature, this review offers a framework to identify the core concepts of outcomes research from database analyses by comparing and contrasting it with the randomized clinical trial.
Canto
J G
JG
Kiefe
C I
CI
Williams
O D
OD
Barron
H V
HV
Rogers
W J
WJ
D015982:Bias; D002309:Cardiology; D015984:Causality; D015331:Cohort Studies; D015986:Confounding Factors, Epidemiologic; D003625:Data Collection; D016208:Databases, Factual; D004992:Ethics, Medical; D006302:Health Services Research; D006801:Humans; D017063:Outcome Assessment, Health Care; D016032:Randomized Controlled Trials as Topic; D012107:Research Design