Psoriatic erythroderma and bullous pemphigoid treated successfully with acitretin and azathioprine.
We present the case of a 59-year-old male patient who developed lesions of a bullous pemphigoid during the course of a long-lasting severe psoriasis which had been treated for years with different topical treatments as well as with PUVA and UV-B radiations. Our patient was successfully treated with a combination of acitretin and azathioprine (follow up 28 months). Our case shows that it is possible to avoid systemic corticosteroid treatment in this difficult therapeutic situation.
Roeder
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Department of Dermatology, University of Erlangen Nuremberg, Hartmannstrasse 14, 91052 Erlangen, Germany.
Driesch
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PV
D017255:Acitretin / Q000627:therapeutic use*; D001379:Azathioprine / Q000627:therapeutic use*; D003873:Dermatitis, Exfoliative / Q000188:drug therapy / Q000473:pathology; D004359:Drug Therapy, Combination; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010391:Pemphigoid, Bullous / Q000188:drug therapy / Q000473:pathology; D011565:Psoriasis / Q000188:drug therapy / Q000473:pathology; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D012871:Skin Diseases / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D007641:Keratolytic Agents; D017255:Acitretin; D001379:Azathioprine