A behavioral stages model of classical (Pavlovian) conditioning: application to cognitive aging.
In the present article, it is argued that a five-stage sequential model of the behavioral and neurophysiological events that occur when organisms are exposed to signals predicting significant events suggests that classical conditioning produces multiple memory traces involving both excitatory and inhibitory processes. Further, these multiple brain structures and associated neurophysiological mechanisms are beginning to be understood; thus, using Pavlovian conditioning techniques to study aging and cognitive functions may provide insights into which brain structures or mechanisms are responsible for more general age-related declines in associative learning and memory. The evidence for this model is briefly reviewed and studies suggesting age-related effects on classical conditioning of various response systems are described within the context of the brain structures implicated by the model.
Powell
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DA
Shirley L. Buchanan Neuroscience Laboratory, Wm. Jennings Bryan Dorn VA Medical Center, Columbia, SC 29209-1639, USA. powell-don@sc.edu
D000375:Aging / Q000502:physiology*; D000818:Animals; D001519:Behavior / Q000502:physiology*; D001522:Behavior, Animal / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D003214:Conditioning, Classical / Q000502:physiology*; D006801:Humans; D008960:Models, Psychological