title: The Agrobacterium tumefaciens chaperone-like protein, VirE1, interacts with VirE2 at domains required for single-stranded DNA binding and cooperative interaction.
abstract: Agrobacterium tumefaciens transfers single-stranded DNA (ssDNA) into plants. Efficient tumorigenesis requires VirE1-dependent export of ssDNA-binding (SSB) protein VirE2. VirE1 binds VirE2 domains involved in SSB and self-association, and VirE1 may facilitate VirE2 export by preventing VirE2 aggregation and the premature binding of VirE2 to ssDNA.
authors.affiliation: Program in Genetics, Oregon State University, Corvallis, Oregon 97331, USA.
authors.forename: C D
authors.initials: CD
authors.lastname: Sundberg
authors.forename: W
authors.initials: W
authors.lastname: Ream
mesh_terms: D016960:Agrobacterium tumefaciens / Q000235:genetics / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism*; D003001:Cloning, Molecular / Q000379:methods; D004277:DNA, Single-Stranded / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D007473:Ion Channels; D018832:Molecular Chaperones / Q000378:metabolism; D010957:Plasmids / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D004277:DNA, Single-Stranded; D004268:DNA-Binding Proteins; D007473:Ion Channels; D018832:Molecular Chaperones; C051582:virE1 protein, Agrobacterium tumefaciens; C051583:virE2 protein, Agrobacterium