title: Current results in off pump surgery.
abstract: OBJECTIVE
  We reviewed our experience with myocardial revascularization without cardiopulmonary by-pass (CPB) to evaluate early- and mid-term results compared with those obtained using CPB.
  
  
  METHODS
  From May 21, 1997 to November 1998, 747 patients had isolated myocardial revascularization, 480 without CPB (Group A) and 267 with CPB (Group B). Exposure of the target vessels was obtained with four slings (two passed through the transverse sinus and two behind the inferior vena cava) and four deep pericardial sutures on the mobile pericardium around the left atrium (Lima stitches). The number of anastomoses/patient (when two or more conduits were used) was higher in Group B (3.1 +/- 1.0 vs 2.6 +/- 0.7, P < 0.001). More marginal branches were grafted in Group A (258 vs 239), but the percentage was higher in Group B (P < 0.001). Crude and risk adjusted mortality was similar in both groups, as well as cerebrovascular accident (CVA) and acute myocardial infarction incidences. Patients in Group A woke earlier, had less inotropes, lower creatinkinase myocardial band (CK-MB) peak, lower bleeding and less transfusion, shorter Intensive Care Unit (ICU) and postoperative stay in hospital than patients in Group B. 266 anastomoses were checked; of these 98.5% were patent and 97.0% were patent and not restrictive.
  
  
  CONCLUSIONS
  Myocardial revascularization without CPB can provide good early- and mid-term results in selected patients. Primary endpoints (death and acute myocardial infarction) were similarly independent from the technique used. Some of the secondary endpoints were favorable in Group A: however their importance is minor. Even if we feel that some high risk patients with severe comorbidities can benefit from CPB surgery; this aspect is difficult to demonstrate scientifically.
authors.affiliation: Department of Cardiac Surgery, University G. D'Annunzio, Chieti, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Contini
authors.forename: A
authors.initials: A
authors.lastname: Iacò
authors.forename: T
authors.initials: T
authors.lastname: Iovino
authors.forename: G
authors.initials: G
authors.lastname: Teodori
authors.forename: G
authors.initials: G
authors.lastname: Di Giammarco
authors.forename: V
authors.initials: V
authors.lastname: Mazzei
authors.forename: M
authors.initials: M
authors.lastname: Commodo
authors.forename: A M
authors.initials: AM
authors.lastname: Calafiore
mesh_terms: D000368:Aged; D002315:Cardiopulmonary Bypass / Q000379:methods* / Q000401:mortality; D005112:Extracorporeal Circulation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000601:surgery*; D009204:Myocardial Revascularization / Q000379:methods* / Q000401:mortality; D011379:Prognosis; D012086:Reoperation; D012680:Sensitivity and Specificity; D016019:Survival Analysis; D015996:Survival Rate