title: Capillary electrophoresis separation and permanganate chemiluminescence on-line detection of some alkaloids with beta-cyclodextrin as an additive.
abstract: Capillary electrophoresis has been used in combination with on-line permanganate chemiluminescence detection for the simultaneous determination of morphine, 6-monoacetylmorphine and heroin. It was found that beta-cyclodextrins could improve the separation efficiency and enhance the chemiluminescence signal. Improved sensitivity over capillary electrophoresis with UV detection was obtained. The procedure has detection limits of 23, 66 and 115 fmol for morphine, 6-monoacetylmorphine and heroin, respectively.
authors.affiliation: Department of Chemistry, Wuhan University, China. zlgong@public.wh.hb.cn
authors.forename: Z
authors.initials: Z
authors.lastname: Gong
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: H
authors.initials: H
authors.lastname: Zhang
authors.forename: J
authors.initials: J
authors.lastname: Cheng
mesh_terms: D000470:Alkaloids / Q000032:analysis*; D003505:Cyclodextrins / Q000032:analysis*; D019075:Electrophoresis, Capillary / Q000379:methods*; D008163:Luminescent Measurements; D017895:Manganese Compounds / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D012680:Sensitivity and Specificity; D047392:beta-Cyclodextrins
chemical_list: D000470:Alkaloids; D003505:Cyclodextrins; D017895:Manganese Compounds; D010087:Oxides; D047392:beta-Cyclodextrins; C048856:permanganic acid; C031215:betadex