title: Bone adaptation to a polyester fiber anterior cruciate ligament replacement.
abstract: A series of polyester fiber ACL implants was studied in ovine stifle joints up to 2 years postimplantation. The implants were linked to the bone-tunnel wall by oriented fibrous tissue. Cross-sections of the tunnels showed bone ingrowth among the implant fibers at 2 years. A human trial of the Apex implant yielded a series of retrievals, some associated with gross bone-tunnel enlargement. There was no evidence of bone ingrowth in the human implants. It was hypothesized that-tunnel enlargement resulted from fretting at the implant-tissue interface in response to cyclic loads in use.
authors.affiliation: Mechanical Engineering Department, Imperial College, London, England. a.amis@ic.ac.uk
authors.forename: A A
authors.initials: AA
authors.lastname: Amis
authors.forename: S A
authors.initials: SA
authors.lastname: Kempson
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D016118:Anterior Cruciate Ligament / Q000601:surgery*; D001672:Biocompatible Materials; D001842:Bone and Bones / Q000473:pathology / Q000503:physiopathology; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D016348:Osseointegration; D011091:Polyesters; D019736:Prostheses and Implants; D016059:Range of Motion, Articular; D012756:Sheep; D013977:Tibia / Q000503:physiopathology* / Q000648:ultrastructure*
chemical_list: D001672:Biocompatible Materials; D011091:Polyesters