[The effect of bemitil on conditioned-reflex memory in normal rats and under stress exposures].
The authors studied the effect of the actoprotector bemitil on the conditional-reflex memory of rats and its functional disorder by disturbance of the cause-effect (abatement of the avoidance reaction) or space relations. Intraperitoneal injections of 1.8 mg/kg of bemitil were given daily 30 min before the experiment. The training of animals improved authentically from experiment to experiment. Thus, the drug, possesses the nootropic properties. Exposure to stressogenic factors of various depth demonstrated the stress-protective effect of bemitil.
Pragina
L L
LL
Moscow State University, Russia.
Tushmalova
N A
NA
Inozemtsev
A N
AN
Smirnov
A V
AV
D000161:Acoustic Stimulation; D000818:Animals; D001562:Benzimidazoles / Q000494:pharmacology*; D003214:Conditioning, Classical / Q000187:drug effects*; D004558:Electric Stimulation; D004924:Escape Reaction / Q000187:drug effects; D008297:Male; D008568:Memory / Q000187:drug effects*; D051381:Rats; D018709:Statistics, Nonparametric; D013312:Stress, Physiological / Q000503:physiopathology*
D001562:Benzimidazoles; C049825:bemethyl