What is the role of botulinum toxin in the treatment of dysthyroid strabismus?
BACKGROUND
Botulinum toxin A has been used in the treatment of dysthyroid strabismus primarily as a temporary measure during the active phase of the disease. We report on our experience with 65 patients.


METHODS
We review the records of 65 patients with dysthyroid strabismus who were treated with botulinum toxin A at Moorfields Eye Hospital between 1984 and 1996.


CONCLUSIONS
Patients with a short duration of relatively mild dysthyroid strabismus have a chance of long-term benefit with botulinum toxin A. There is little use for botulinum toxin A in cases of severe dysthyroid disease.
Gair
E J
EJ
Moorfields Eye Hospital, London, England, United Kingdom.
Lee
J P
JP
Khoo
B K
BK
Maurino
V
V
D000328:Adult; D000368:Aged; D018726:Anti-Dyskinesia Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006111:Graves Disease / Q000150:complications*; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D009801:Oculomotor Muscles / Q000187:drug effects*; D012189:Retrospective Studies; D013285:Strabismus / Q000188:drug therapy* / Q000209:etiology; D016896:Treatment Outcome
D018726:Anti-Dyskinesia Agents; D019274:Botulinum Toxins, Type A