title: Complications associated with percutaneous closure devices.
abstract: BACKGROUND
  In an effort to reduce time to hemostasis after angiography, several closure devices have been marketed. We report some of their complications.
  
  
  METHODS
  A retrospective review was conducted.
  
  
  RESULTS
  Over an 8-month study period, 2,181 diagnostic and interventional procedures were performed. Closure devices were used in 408 (19%) of these patients. The Angio-Seal closure device is composed of a collagen sponge and an absorbable polymer anchor that compresses the hole in the arteriotomy. The ProstarXL sealing device consists of a rotating barrel that deploys 4 needles through the arteriotomy, and then individual knots are extracorporeally tied. The Duett device consists of a balloon occluding catheter and injectable collagen and thrombin. Ten of the patients developed a complication from the closure device (2.5%). Four of these were subcutaneous abscesses. Two of these patients had expanding pseudaneurysms, 2 had lower extremity ischemia, and 1 patient had an acute bleed. These complications were all managed surgically. Another patient developed a retroperitoneal bleed that was managed nonoperatively.
  
  
  CONCLUSIONS
  As the use of these devices increase, these complications will become more common.
authors.affiliation: Department of Surgery, Ochsner Medical Institutions, New Orleans, Louisiana 70121, USA.
authors.forename: M D
authors.initials: MD
authors.lastname: Gonze
authors.forename: W C
authors.initials: WC
authors.lastname: Sternbergh
authors.forename: K
authors.initials: K
authors.lastname: Salartash
authors.forename: S R
authors.initials: SR
authors.lastname: Money
mesh_terms: D006489:Hemostatic Techniques / Q000009:adverse effects* / Q000295:instrumentation*; D006801:Humans; D012189:Retrospective Studies; D013536:Suture Techniques / Q000009:adverse effects* / Q000295:instrumentation*