[The participation of the striatum in the central regulation of gonadal hormonal function].
Intrastriatal corticotrophin-releasing hormone (CRH) was shown to induce a decrease in the plasma tectosterone concentration. Besides, the 6-OHDA pre-treatment completely prevented the suppression of plasma testosterone in response to intrastriatal CRH administration. The findings suggest that the striatum is involved in the extrahypothalamic regulation of the gonadal endocrine function.
Rybnikova
E A
EA
I. P. Pavlov Institute of Physiology, Russian Acad. Sci., St. Petersburg, Russia.
Rakitskaia
V V
VV
Shaliapina
V G
VG
D018663:Adrenergic Agents / Q000494:pharmacology; D000818:Animals; D003342:Corpus Striatum / Q000187:drug effects / Q000502:physiology*; D003346:Corticotropin-Releasing Hormone / Q000494:pharmacology; D004347:Drug Interactions; D008297:Male; D008845:Microinjections; D016627:Oxidopamine / Q000494:pharmacology; D011374:Progesterone / Q000097:blood; D051381:Rats; D017208:Rats, Wistar; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology; D013737:Testis / Q000187:drug effects / Q000502:physiology*; D013739:Testosterone / Q000097:blood / Q000502:physiology*
D018663:Adrenergic Agents; D011954:Receptors, Dopamine; D013739:Testosterone; D011374:Progesterone; D016627:Oxidopamine; D003346:Corticotropin-Releasing Hormone