Hemodynamics and wall mechanics after stent placement in swine iliac arteries: comparative results from six stent designs.
OBJECTIVE
To compare the hemodynamics and wall mechanics of swine iliac arteries after placement of six types of stent.


METHODS
Stents were placed in the iliac artery of 18 pigs (three pigs each underwent placement with one of six types of stent); 16 untreated pigs served as control animals. Iliac arterial hemodynamics and wall mechanics were measured 4 days after placement.


RESULTS
Four stents (Palmaz-Schatz, Cordis, Warren, NJ; and Strecker, Cragg, and Symphony, Boston Scientific/Vascular, Natick, Mass) caused decreased pulsatile flow rate in the treated and contralateral iliac arteries; one (Memotherm; Bard, Covington, Ga) caused increased flow pulsatility; and one (Wallstent; Schneider, Plymouth, Minn) had no effect. No compliance mismatching was noted for the Cragg, Symphony, and Memotherm stents, whereas a decrease in compliance was noted for the Palmaz-Schatz, Strecker, and Wallstent designs. The Palmaz-Schatz and Strecker stents caused increased arterial wall rigidity, the Symphony and Wallstent designs had no effect, and the Memotherm and Cragg stents caused decreased wall rigidity. Stents made of stiff metal yielded different early results than did stents made of the less rigid nitinol.


CONCLUSIONS
Soon after implantation, the six stent designs elicited varying changes in blood flow, arterial compliance, and arterial wall mechanics. Contralateral arterial flow also was affected.
Rolland
P H
PH
Hemodynamics and Cardiovascular Mechanics Laboratory, Faculte de Medicine, Marseille, France. lab.hmcv@medecine.univ-mrs.fr
Charifi
A B
AB
Verrier
C
C
Bodard
H
H
Friggi
A
A
Piquet
P
P
Moulin
G
G
Bartoli
J M
JM
D000818:Animals; D001783:Blood Flow Velocity; D003187:Compliance; D004548:Elasticity; D004867:Equipment Design; D006439:Hemodynamics; D007083:Iliac Artery / Q000000981:diagnostic imaging / Q000502:physiology*; D011312:Pressure; D011673:Pulsatile Flow; D011856:Radiographic Image Enhancement; D015607:Stents; D013552:Swine; D014654:Vascular Patency