title: [The current state on development of novel vitamin derivatives].
abstract: In this review, we outline the current state on developments of novel vitamin A, C and D derivatives. We focused on the topics obtained with these novel vitamin A derivatives in relation to cell differentiation, apoptosis and gene regulation. As for vitamin D derivatives, the results obtained on cell differentiation and calcium metabolism were summarized. Lastly, we described some stable ascorbates, and further introduced stable (AA-2G) and lipophilic (6-Acyl-AA-2G) derivatives which have been recently developed in our laboratory. Both of them were demonstrated by us to express vitamin C activity in vivo.
authors.affiliation: Department of Immunochemistry, Faculty of Pharmaceutical Sciences, Okayama University.
authors.forename: I
authors.initials: I
authors.lastname: Yamamoto
authors.forename: A
authors.initials: A
authors.lastname: Tai
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology*; D006801:Humans; D014212:Tretinoin / Q000494:pharmacology*; D014807:Vitamin D / Q000494:pharmacology*
chemical_list: D014807:Vitamin D; D014212:Tretinoin; D001205:Ascorbic Acid