title: SWItched-on mobility.
abstract: Recent studies have shown that two nucleosome-remodeling complexes, NURF and CHRAC, open chromatin for transcription and replication by using their common catalytic subunit, the nucleosomal ATPase ISWI, to increase the mobility of nucleosomes relative to DNA sequence.
authors.affiliation: Laboratory of Molecular Embryology National Institute of Child Health and Human Development National Institutes of Health Building 18T, Room 106, Bethesda, Maryland, 20892-5431, USA.
authors.forename: D
authors.initials: D
authors.lastname: Guschin
authors.forename: A P
authors.initials: AP
authors.lastname: Wolffe
mesh_terms: D000251:Adenosine Triphosphatases / Q000737:chemistry / Q000502:physiology*; D000818:Animals; D002843:Chromatin / Q000502:physiology*; D002868:Chromosomal Proteins, Non-Histone; D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D006657:Histones / Q000502:physiology; D019476:Insect Proteins / Q000737:chemistry / Q000502:physiology*; D008958:Models, Molecular; D018832:Molecular Chaperones; D009687:Nuclear Proteins; D009707:Nucleosomes / Q000502:physiology*; D011755:Pyrophosphatases; D056505:Retinoblastoma-Binding Protein 4; D014157:Transcription Factors / Q000737:chemistry / Q000502:physiology*; D014158:Transcription, Genetic
chemical_list: C110251:Caf1-55 protein, Drosophila; D002843:Chromatin; D002868:Chromosomal Proteins, Non-Histone; D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D006657:Histones; C086468:ISWI protein; D019476:Insect Proteins; D018832:Molecular Chaperones; D009687:Nuclear Proteins; D009707:Nucleosomes; D056505:Retinoblastoma-Binding Protein 4; D014157:Transcription Factors; D000251:Adenosine Triphosphatases; D011755:Pyrophosphatases; C115568:Nurf-38 protein, Drosophila