title: Cardiac output and ductal reopening during phototherapy in preterm infants.
abstract: Left ventricular output (LVO), left pulmonary artery blood flow (LPA) and patency of the ductus arteriosus (PDA) were studied with 2D/pulsed Doppler ultrasound before, during and after phototherapy treatment in 27 preterm infants (gestational age < or =32 wk), who were exposed for a minimum of 12 h to phototherapy for non-haemolytic hyperbilirubinemia. In 14 infants (52%) the ductus arteriosus reopened during phototherapy, but ductal patency was not of haemodynamic importance. LVO initially decreased in preterm infants in whom the ductus did not reopen. From 12 h until discontinuation of phototherapy, LVO and LPA were higher than before phototherapy in all infants. After withdrawal of phototherapy, LVO and LPA returned to pre-phototherapy values.
authors.affiliation: Department of Pediatrics, Leiden University Medical Center, The Netherlands.
authors.forename: M J
authors.initials: MJ
authors.lastname: Benders
authors.forename: F
authors.initials: F
authors.lastname: Van Bel
authors.forename: M
authors.initials: M
authors.lastname: Van de Bor
mesh_terms: D000704:Analysis of Variance; D001724:Birth Weight; D001783:Blood Flow Velocity; D001794:Blood Pressure; D002302:Cardiac Output; D002303:Cardiac Output, Low / Q000209:etiology; D004374:Ductus Arteriosus, Patent / Q000209:etiology*; D005865:Gestational Age; D006339:Heart Rate; D006801:Humans; D006932:Hyperbilirubinemia / Q000628:therapy*; D007231:Infant, Newborn; D007234:Infant, Premature; D010789:Phototherapy / Q000009:adverse effects*; D012008:Recurrence