[A morphological and electron radioautographic study of the wound in the diabetic foot syndrome].
Two groups of patients with a grave form of diabetes mellitus type I and II with diabetic foot syndrome have been examined. Group 1 (21 cases) consisted of patients whose foot was amputated. The cause of the necrotic process was ischemia produced by alteration of the arterial vessels aggravated by infection. Patients of group 2 (18 cases) were treated with resultant wound healing and foot preservation. The material was subdivided into two subgroups: 1) tissue from the "infectious" foot with great amount of bacteria and inflammation reaction; 2) tissue from the "ischemic" foot with considerable alterations of microvessels structure. In both groups well developed granulation tissue was observed after the treatment; almost all the cells of this tissue included 3H-uridin and labelling with 3H-thymidine was increased in fibroblasts, endotheliocytes and pericytes.
Kolokol'chikova
E G
EG
A. V. Vishnevsky Institute of Surgery, Moscow.
Pal'tsyn
A A
AA
Panova
N V
NV
Svetukhin
A M
AM
Zemlianoĭ
A B
AB
Chervonskaia
N V
NV
Badikova
A K
AK
Puchkova
L S
LS
D000328:Adult; D000368:Aged; D000671:Amputation, Surgical; D001345:Autoradiography; D001706:Biopsy; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000473:pathology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000473:pathology; D017719:Diabetic Foot / Q000473:pathology* / Q000601:surgery; D005528:Foot / Q000473:pathology; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D009336:Necrosis