title: Prothrombotic state and elevated levels of plasminogen activator inhibitor-1 in mitral stenosis with and without atrial fibrillation.
abstract: Patients with mitral stenosis in sinus rhythm are in a prothrombotic state and have fibrinolytic dysfunction, shown by an increase in levels of the inhibitor of tissue plasminogen activator, D-dimer, and modified antithrombin III. This state may be observed even in patients without dilated left atria (diameter < or =45 mm).
authors.affiliation: Department of Cardiology, General Hospital of Elche, Alicante, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Marín
authors.forename: V
authors.initials: V
authors.lastname: Roldán
authors.forename: J V
authors.initials: JV
authors.lastname: Monmeneu
authors.forename: V
authors.initials: V
authors.lastname: Bodí
authors.forename: C
authors.initials: C
authors.lastname: Fernández
authors.forename: F G
authors.initials: FG
authors.lastname: de Burgos
authors.forename: P
authors.initials: P
authors.lastname: Marco
authors.forename: F
authors.initials: F
authors.lastname: Sogorb
mesh_terms: D001281:Atrial Fibrillation / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism*; D004452:Echocardiography; D005260:Female; D005337:Fibrin / Q000378:metabolism; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism*; D017395:Plasminogen Activator Inhibitor 1 / Q000378:metabolism*; D018709:Statistics, Nonparametric; D013917:Thrombin / Q000378:metabolism; D010959:Tissue Plasminogen Activator / Q000378:metabolism
chemical_list: D017395:Plasminogen Activator Inhibitor 1; D005337:Fibrin; D013917:Thrombin; D010959:Tissue Plasminogen Activator