title: [Methods of autologous peripheral blood stem cell (PBSC) mobilization in oncological and hematological patients].
abstract: The potential of peripheral blood stem cell (PBSC) mobilization with granulocyte (G-CSF) and granulocyte-macrophage (GM-CSF) colony-stimulating factors of chemotherapy has been assessed in patients with tumor or hematological disease. The study was intended to aid PBSC transplantation. It was shown that G-CSF administration increased the number of leukocytes in leukemia patients dramatically while mononuclear cell and colony-forming unit levels in G-CSF-mobilised PBSC were significantly higher than those collected with GM-CSF or chemotherapy.
authors.affiliation: Acad. I.P. Pavlov State Medical University, St. Petersburg.
authors.forename: L M
authors.initials: LM
authors.lastname: Fregatova
authors.forename: S A
authors.initials: SA
authors.lastname: Shavva
authors.forename: G G
authors.initials: GG
authors.lastname: Platonova
authors.forename: A A
authors.initials: AA
authors.lastname: Golovacheva
authors.forename: B V
authors.initials: BV
authors.lastname: Afanas'ev
mesh_terms: D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use*; D006402:Hematologic Diseases / Q000097:blood* / Q000628:therapy; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods*; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells; D006801:Humans; D007962:Leukocytes / Q000187:drug effects*; D009369:Neoplasms / Q000097:blood* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D016179:Granulocyte Colony-Stimulating Factor; D016178:Granulocyte-Macrophage Colony-Stimulating Factor