Prevention and treatment of microvascular and neuropathic complications of diabetes.
The most important factors that influence development of the eye, kidney, and nerve complications of diabetes are the duration and degree of exposure to hyperglycemia. Hypertension is also very important. The risk of complications appears to be similar for all patients with diabetes; differences in complication rates between patients with type 1 and type 2 diabetes are largely due to differences in duration of diabetes and glycemic control. The benefits of lowering blood sugar are also similar for patients with diabetes, regardless of the type. Significant reductions in complications can be seen with relatively short-term treatment of hyperglycemia.
Eastman
R C
RC
National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892, USA. Eastmand@extra.niddk.nih.gov
Garfield
S A
SA
D001786:Blood Glucose / Q000378:metabolism; D002986:Clinical Trials as Topic; D003925:Diabetic Angiopathies / Q000097:blood / Q000517:prevention & control* / Q000628:therapy*; D003929:Diabetic Neuropathies / Q000097:blood / Q000517:prevention & control* / Q000628:therapy*; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000517:prevention & control / Q000628:therapy; D008297:Male; D012307:Risk Factors
D001786:Blood Glucose