title: [Anesthetic management of a patient with Coffin-Lowry syndrome].
abstract: Coffin-Lowry syndrome (CLS) is characterized by mental retardation, a peculiar face and deformities of the thorax and spine. A 33-year-old female with Coffin-Lowry syndrome (CLS), further complicated with atrial septal defect and ventricular tachycardia, underwent elective surgery for anterior cervical cyst. As difficult intubation had been anticipated, anesthesia was induced with continuous administration of propofol. After confirming that she could be ventilated by mask, vecuronium bromide, midazolam and fentanyl were given. The operation and anesthesia were conducted uneventfully. No complications occurred postoperatively. The use of propofol for slow induction of anesthesia was advantageous for hemodynamic stability in this case.
authors.affiliation: Department of Dental Anesthesiology, Osaka University, Faculty of Dentistry, Suita.
authors.forename: K
authors.initials: K
authors.lastname: Hashiguchi
authors.forename: T
authors.initials: T
authors.lastname: O'Higashi
authors.forename: S
authors.initials: S
authors.lastname: Sasai
authors.forename: T
authors.initials: T
authors.lastname: Kiguchi
authors.forename: H
authors.initials: H
authors.lastname: Uga
authors.forename: H
authors.initials: H
authors.lastname: Matsuura
mesh_terms: D000015:Abnormalities, Multiple; D000328:Adult; D000768:Anesthesia, General; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D019465:Craniofacial Abnormalities; D003560:Cysts / Q000601:surgery; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000150:complications; D006801:Humans; D008607:Intellectual Disability; D007442:Intubation, Intratracheal; D009333:Neck; D015742:Propofol / Q000008:administration & dosage; D013131:Spine / Q000002:abnormalities*; D013577:Syndrome; D017180:Tachycardia, Ventricular / Q000150:complications; D013909:Thorax / Q000002:abnormalities*
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol