[The experimental and clinical validation of the use of a polikatan preparation in periodontal diseases].
Polycatane, a bischofite-based drug (bischofite is a mineral containing up to 95% dry residue of MgCl2 x 6H2O), exerted antiinflammatory and bacteriostatic effects and stimulated phagocytosis and healing of burn infected ulcer in the buccal mucosa of experimental animals. The drug was effective in the treatment of patients with chronic catarrhal gingivitis and generalized periodontitis of light and medium severity. By its antiinflammatory and wound-healing effects polycatane is superior to polyminerol, the reference drug.
Spasov
A A
AA
Temkin
E S
ES
Ostrovskiĭ
O V
OV
Kalinina
N V
NV
Gerchikov
L V
LV
Mikhal'chenko
V F
VF
Demina
L V
LV
D000276:Adjuvants, Immunologic / Q000494:pharmacology / Q000627:therapeutic use*; D000328:Adult; D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002056:Burns / Q000188:drug therapy; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D004487:Edema / Q000188:drug therapy; D005260:Female; D006801:Humans; D008274:Magnesium / Q000627:therapeutic use; D015636:Magnesium Chloride / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D008826:Microbial Sensitivity Tests / Q000706:statistics & numerical data; D008875:Middle Aged; D008903:Minerals; D009059:Mouth Diseases / Q000188:drug therapy; D010510:Periodontal Diseases / Q000188:drug therapy*; D010587:Phagocytosis / Q000187:drug effects; D011817:Rabbits; D051381:Rats
D000276:Adjuvants, Immunologic; D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D004338:Drug Combinations; D008903:Minerals; C072517:bishofit; D015636:Magnesium Chloride; D008274:Magnesium