title: Three-dimensional bone structure around hydroxyapatite and titanium implants in rabbits.
abstract: Long-term support of dental implants requires adequate bone thickness in the area surrounding the implant. A three-dimensional examination, including calculations of percent bone-implant contact and percent bone volume, was conducted to clarify the bone structure around pure titanium (Ti) and dense hydroxyapatite (HA) implants. The implants were installed in the tibiae of rabbits, and the bone structure was examined after 2, 4, 6 and 8 weeks. The bone formation following implantation differed in the cortical bone and cancellous bone areas. In the cortical bone area, the percent bone-implant contact and percent bone volume were comparatively consistent for both Ti and HA implants during the observation period. In the cancellous bone area, both findings were influenced by the implantation period, and the chronological bone structure in the cancellous bone area also differed between Ti and HA implants. The percent bone-implant contact and percent bone volume in the Ti implant increased over 8 weeks, whereas the dense HA implant increased for the first 4 weeks and then decreased. The implant materials, Ti and HA, affected the bone remodeling in the cancellous bone area.
authors.affiliation: Department of Removable Prosthodontics, University of Tokushima, School of Dentistry, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Wigianto
authors.forename: T
authors.initials: T
authors.lastname: Ichikawa
authors.forename: H
authors.initials: H
authors.lastname: Kanitani
authors.forename: N
authors.initials: N
authors.lastname: Kawamoto
authors.forename: N
authors.initials: N
authors.lastname: Matsumoto
authors.forename: H
authors.initials: H
authors.lastname: Ishizuka
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D015519:Bone Density; D016723:Bone Remodeling / Q000502:physiology; D003196:Computer Graphics; D003758:Dental Implantation, Endosseous; D017886:Durapatite; D007091:Image Processing, Computer-Assisted; D020007:Implants, Experimental; D008297:Male; D016348:Osseointegration / Q000502:physiology*; D011817:Rabbits; D013977:Tibia; D014025:Titanium
chemical_list: D017886:Durapatite; D014025:Titanium