title: Cashing in on crystals.
abstract: Structures of the ribosome and its two subunits have been determined by X-ray crystallography at resolutions sufficient to reveal interactions between RNA and protein in the subunits and orientations of substrates at the subunit interface in the intact ribosome.
authors.affiliation: Howard Hughes Medical Institute Department of Molecular Biophysics and Biochemistry Yale University New Haven, Connecticut, 06511, USA. doudna@csb.yale.edu.
authors.forename: J A
authors.initials: JA
authors.lastname: Doudna
mesh_terms: D018360:Crystallography, X-Ray; D019614:Haloarcula marismortui / Q000737:chemistry / Q000648:ultrastructure; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000737:chemistry* / Q000502:physiology / Q000648:ultrastructure; D012343:RNA, Transfer / Q000737:chemistry / Q000502:physiology / Q000648:ultrastructure; D012270:Ribosomes / Q000737:chemistry* / Q000502:physiology / Q000648:ultrastructure; D016963:Thermus thermophilus / Q000737:chemistry / Q000648:ultrastructure
chemical_list: D012333:RNA, Messenger; D012343:RNA, Transfer