[The model of the rate of radiation-induced mammalian death based on the determination of delayed consequences of different doses of radiation].
Analyzed were model descriptions of the probability of mammalian lethality and a possible life span reduction consequent to acute and chronic exposures to different dose rates. The proposed model of radiation rate of mammalian death links variations of the coefficient of mammalian death due to acute and prolonged radiation exposures with age. Application of the model to relevant experimental data yielded model coefficients for these periods of exposure. The radiation-modified dependence of lethality coefficients on age makes it possible to obtain fairly simple analytical expressions describing the survival probability long after exposure as a function of dose and dose rate, estimating radiation risk at any time point following exposure, and shortening of mean life span associated with exposure to different doses.
Shafirkin
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D000208:Acute Disease; D000818:Animals; D002908:Chronic Disease; D004307:Dose-Response Relationship, Radiation; D005500:Follow-Up Studies; D008322:Mammals / Q000502:physiology*; D008954:Models, Biological; D011833:Radiation Injuries, Experimental / Q000401:mortality*