Reproductive risk factors for mucinous and non-mucinous epithelial ovarian cancer.
We evaluated reproductive risk factors for mucinous and non-mucinous tumors in a population-based case-control study of epithelial ovarian cancer among women ages 20-79 years. We observed a reduction in risk of tumors of both types in association with one or more full-term pregnancies and with use of oral contraceptives for 5 or more years. While findings of some previous studies support the hypothesis that certain aspects of a woman's reproductive life have a different impact on the risk of these subtypes of ovarian epithelial cancer, our data suggest that this issue is not yet resolved.
Wittenberg
J
J
National Organization for Quality Improvement in Health Care, Utrecht, The Netherlands.
Cook
L S
LS
Rossing
M A
MA
Weiss
N S
NS
Wittenberg
L
L
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D009375:Neoplasms, Glandular and Epithelial / Q000453:epidemiology*; D010051:Ovarian Neoplasms / Q000453:epidemiology*; D010298:Parity; D012307:Risk Factors; D013246:Sterilization, Tubal; D014861:Washington / Q000453:epidemiology