[Thymic cyst with elevated SLX levels in serum and cystic fluid].
A 24-year-old man was admitted to our hospital in June 1996 with complaints of anterior chest discomfort. Chest X-ray films on admission showed an abnormal mediastinal shadow with well-defined margin. Chest X-ray examinations about 6 weeks earlier had not detected any abnormalities. Laboratory tests on admission showed a high serum concentration of Siaryl Lewis X-i antigen (SLX). A computed tomographic scan of the chest showed a large (6 x 6 x 12 cm) homogeneous mass in the right anterior mediastinum. The mass was removed completely and histologically diagnosed as a thymic cyst. Biochemical analysis of fluid from the cyst revealed remarkably high levels of SLX, CA 19-9, and CEA. In immunohistochemical studies, epithelial cells from the cystic walls stained positive for SLX, CA 19-9, and CEA. After the operation, the level of serum SLX returned almost to normal.
Ishii
H
H
Third Department of Internal Medicine, Miyazaki Medical College, Kiyotake, Japan.
Mukae
H
H
Ashitani
J
J
Mashimoto
H
H
Matsukura
S
S
Ichinari
H
H
Matuzaki
Y
Y
Kadota
J
J
Kohno
S
S
D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000097:blood; D006801:Humans; D016256:Lewis X Antigen / Q000032:analysis*; D008297:Male; D008476:Mediastinal Cyst / Q000175:diagnosis* / Q000601:surgery
D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D016256:Lewis X Antigen