Psychopharmacology in supportive care in cancer: a review for the clinician. I. Benzodiazepines.
Benzodiazepines are widely utilized in the cancer setting. Most aspects relevant to their use in supportive care are reviewed to assist the clinical oncologist in prescribing such drugs. This review covers pharmacokinetics, indications, adverse effects and drug interactions, and compares the profiles of different benzodiazepines. Finally, controversial issues with regard to benzodiazepines are discussed.
Stiefel
F
F
Service de Psychiatrie de Liaison, CHUV, CH-1011 Lausanne, Switzerland.
Berney
A
A
Mazzocato
C
C
D014151:Anti-Anxiety Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001521:Behavior Therapy; D001569:Benzodiazepines; D002492:Central Nervous System Depressants / Q000009:adverse effects; D004347:Drug Interactions; D018757:GABA Modulators / Q000493:pharmacokinetics; D006801:Humans; D009369:Neoplasms / Q000523:psychology* / Q000628:therapy; D013315:Stress, Psychological / Q000188:drug therapy / Q000628:therapy; D013375:Substance Withdrawal Syndrome / Q000209:etiology
D014151:Anti-Anxiety Agents; D002492:Central Nervous System Depressants; D018757:GABA Modulators; D001569:Benzodiazepines