title: Experimental 3D dosimetry around a high-dose-rate clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter.
abstract: It is well known that the experimental dosimetry of brachytherapy sources presents a challenge. Depending on the particular-dosimeter used, measurements can suffer from poor spatial resolution (ion chambers), lack of 3D information (film) or errors due to the presence of the dosimeter itself distorting the radiation flux. To avoid these problems, we have investigated the dosimetry of a clinical 192Ir source using a polyacrylamide gel (PAG) dosimeter. Experimental measurements of dose versus radial distance from the centre of the source (cross-line plots) were compared with calculations produced with a Nucletron NPS planning system. Good agreement was found between the planning system and gel measurements in planes selected for analysis. Gel dosimeter measurements in a coronal plane through the phantom showed a mean difference between measured absorbed dose and calculated dose of 0.17 Gy with SD = 0.13 Gy. Spatially, the errors at the reference point remain within one image pixel (1.0 mm). The use of polymer gel dosimetry shows promise for brachytherapy applications, offering complete, three-dimensional dose information, good spatial resolution and small measurement errors. Measurements close to the source, however, are difficult, due to some of the limiting properties of the polyacrylamide gel.
authors.affiliation: Joint Department of Physics, The Institute of Cancer Research and The Royal Marsden Hospital NHS Trust, Sutton, Surrey, UK.
authors.forename: M
authors.initials: M
authors.lastname: McJury
authors.forename: P D
authors.initials: PD
authors.lastname: Tapper
authors.forename: V P
authors.initials: VP
authors.lastname: Cosgrove
authors.forename: P S
authors.initials: PS
authors.lastname: Murphy
authors.forename: S
authors.initials: S
authors.lastname: Griffin
authors.forename: M O
authors.initials: MO
authors.lastname: Leach
authors.forename: S
authors.initials: S
authors.lastname: Webb
authors.forename: M
authors.initials: M
authors.lastname: Oldham
mesh_terms: D000180:Acrylic Resins; D001918:Brachytherapy / Q000379:methods*; D002138:Calibration; D005782:Gels; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D019047:Phantoms, Imaging; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D000099166:Polyacrylamides
chemical_list: D000180:Acrylic Resins; D005782:Gels; D007496:Iridium Radioisotopes; D000099166:Polyacrylamides