Successful treatment of Kimura's disease with cyclosporine.
We report the case of a 29-year-old Japanese woman presenting with recurring Kimura's disease. We began treatment with cyclosporine within 7 days, the nodular lesion had almost cleared. The cyclosporine dose was then gradually reduced and discontinued after 6 months. The patient was reassessed 18 months after the cessation of treatment and there was no evidence of recurrence of the disease. We speculate that the effects of cyclosporine on T helper-2 cells improves Kimura's disease.
Kaneko
K
K
Department of Dermatology, Nippon Medical School, Tokyo, Japan. pst@nms.ac.jp
Aoki
M
M
Hattori
S
S
Sato
M
M
Kawana
S
S
D000328:Adult; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000188:drug therapy* / Q000473:pathology; D016572:Cyclosporine / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004427:Ear Diseases / Q000188:drug therapy* / Q000473:pathology; D004431:Ear, External; D005260:Female; D006801:Humans
D003879:Dermatologic Agents; D016572:Cyclosporine