title: [Present possibilities of prevention of adhesions and their immunologic aspects].
abstract: The study reviews recent developments with regard to postsurgical adhesion formation, the role of some cytokines and possible prevention. Interleukin-1 beta (IL-1 beta) levels in peritoneal fluid were assayed during 24 and 48 hours after laparoscopic or laparotomic surgery and the influence of diclofenac was evaluated. IL-1 beta levels in peritoneal fluid were substantially lower after laparoscopic adnexal surgery than after laparotomy. Application of diclofenac after abdominal hysterectomies reduced substantially intraperitoneal IL-1 beta levels.
authors.affiliation: I. gynek.-porod. klinika LF MU, Brno.
authors.forename: I
authors.initials: I
authors.lastname: Crha
authors.forename: P
authors.initials: P
authors.lastname: Ventruba
authors.forename: M
authors.initials: M
authors.lastname: Petrenko
authors.forename: H
authors.initials: H
authors.lastname: Visnová
mesh_terms: D000328:Adult; D016207:Cytokines / Q000502:physiology*; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D010532:Peritoneal Diseases / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D000267:Tissue Adhesions / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control
chemical_list: D016207:Cytokines