title: Determinants of aggression, and adaptive and maladaptive behaviour in older people with Down's syndrome with and without dementia.
abstract: In a cross-sectional study of aggression, and adaptive and maladaptive behaviour in 128 subjects with Down's syndrome (DS), 29 of whom had dementia, the current authors found that the presence of dementia was not predictive of aggression or maladaptive behaviour. However, the level of adaptive behaviour was shown to be lower in subjects with dementia, and in those with lower levels of cognitive functioning, as measured on a rating instrument, the Test for Severe Impairment. Although the presence of aggressive behaviours is not higher in subjects with dementia and DS on cross-sectional review, it remains to be seen whether aggression will increase in individual cases with the onset or progression of dementia. The decline in adaptive behaviour shown in the present study confirms the findings of previous studies and indicates a direction for service development for persons with the dual diagnosis of dementia and DS.
authors.affiliation: Department of Old Age Psychiatry, St Patrick's Hospital, Dublin, Ireland.
authors.forename: M P
authors.initials: MP
authors.lastname: Cosgrave
authors.forename: J
authors.initials: J
authors.lastname: Tyrrell
authors.forename: M
authors.initials: M
authors.lastname: McCarron
authors.forename: M
authors.initials: M
authors.lastname: Gill
authors.forename: B A
authors.initials: BA
authors.lastname: Lawlor
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000374:Aggression; D003430:Cross-Sectional Studies; D003704:Dementia / Q000150:complications*; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D007494:Ireland / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D017678:Sex Distribution; D012917:Social Adjustment; D012920:Social Behavior Disorders / Q000150:complications / Q000453:epidemiology*