Wasalexins A and B, new phytoalexins from wasabi: isolation, synthesis, and antifungal activity.
The chemical structure determination of two phytoalexins from wasabi (Wasabia japonica, syn. Eutrema wasabi), a plant resistant to virulent isolates of the blackleg fungus [Leptosphaeria maculans (Desm.) Ces. et de Not., asexual stage Phoma lingam (Tode ex Fr.) Desm.], as well as their synthesis and antifungal activity towards isolates of P. lingam and P. wasabiae is reported.
Pedras
M S
MS
Department of Chemistry, University of Saskatchewan, Saskatoon, SK, Canada.
Sorensen
J L
JL
Okanga
F I
FI
Zaharia
I L
IL
D000935:Antifungal Agents / Q000138:chemical synthesis / Q000302:isolation & purification* / Q000494:pharmacology; D019607:Brassicaceae / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D013440:Sulfides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000935:Antifungal Agents; D007211:Indoles; D013440:Sulfides; C401941:wasalexin A