title: Hb Bologna-St. Orsola [beta146(HC3)His-->Tyr]: a new high oxygen affinity variant with halved Bohr effect and highly reduced reactivity towards 2,3-diphosphoglycerate.
authors.affiliation: Laboratorio Genetica Umana, Ospedali Galliera, Genova, Italia. g.ivaldi@galliera.it
authors.forename: G
authors.initials: G
authors.lastname: Ivaldi
authors.forename: O
authors.initials: O
authors.lastname: David
authors.forename: V
authors.initials: V
authors.lastname: Paradossi
authors.forename: M
authors.initials: M
authors.lastname: Baffico
authors.forename: V
authors.initials: V
authors.lastname: Scimè Degani
authors.forename: D
authors.initials: D
authors.lastname: Leone
authors.forename: M
authors.initials: M
authors.lastname: Baldi
authors.forename: M I
authors.initials: MI
authors.lastname: Parodi
authors.forename: P
authors.initials: P
authors.lastname: Bernardi
authors.forename: G
authors.initials: G
authors.lastname: Ricco
mesh_terms: D019794:2,3-Diphosphoglycerate / Q000097:blood*; D000293:Adolescent; D000494:Allosteric Regulation; D019943:Amino Acid Substitution; D005260:Female; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006639:Histidine / Q000737:chemistry*; D006801:Humans; D008297:Male; D010100:Oxygen / Q000097:blood*; D017354:Point Mutation; D017422:Sequence Analysis, DNA; D014443:Tyrosine / Q000737:chemistry*
chemical_list: D006455:Hemoglobins, Abnormal; D019794:2,3-Diphosphoglycerate; D014443:Tyrosine; D006639:Histidine; C031005:hemoglobin Bologna; D010100:Oxygen