Nasopharyngeal teratoma and mosaic tetrasomy 1q detected at amniocentesis. A case report and review of the literature.
The occurrence of nasopharyngeal teratomas (NPT) is an infrequent event and prenatal detection of such tumors is even rarer. We present a case report and review of the literature (N = 78 cases), in which we describe the cytogenetic, DNA, and pathological findings of a fetus with a mature NPT which was detected prenatally by ultrasound investigation following complaints of severe polyhydramnios by the mother.
Beverstock
G C
GC
Department of Clinical Cytogenetics, Leiden University Medical Centre, The Netherlands.
Mollevanger
P
P
Baaij
M
M
Lind
J
J
van Ieperen
L
L
Bartelings
M M
MM
Teunissen
K
K
Brandenburg
H
H
Van Opstal
D
D
Los
F
F
D000328:Adult; D000649:Amniocentesis; D000782:Aneuploidy; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D009303:Nasopharyngeal Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics*; D006831:Polyhydramnios; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D013724:Teratoma / Q000000981:diagnostic imaging / Q000235:genetics*; D014463:Ultrasonography