Lack of association between schizophrenia and a pancreatic phospholipase A-2 gene (PLA2G1B) polymorphism.
Patients with schizophrenia (DSM IV, n = 149) and controls (n = 180) participated in a case-control association study in which a trinucleotide repeat polymorphism of pancreatic phospholipase A2 group 1B (PLA2G1B) was examined. Both African-American and Caucasian populations were included in this USA sample. There were no significant case-control differences, therefore his study does not support an association between schizophrenia and a PLA2G1B polymorphism on chromosome 12.
Strauss
J
J
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA.
Zhang
X R
XR
Barron
Y
Y
Ganguli
R
R
Nimgaonkar
V L
VL
D000328:Adult; D044383:Black People / Q000235:genetics; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D004247:DNA / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D010179:Pancreas / Q000201:enzymology*; D010741:Phospholipases A / Q000235:genetics*; D054467:Phospholipases A2; D011110:Polymorphism, Genetic; D012016:Reference Values; D012189:Retrospective Studies; D012559:Schizophrenia / Q000201:enzymology / Q000235:genetics*; D018911:Trinucleotide Repeats; D014481:United States; D044465:White People / Q000235:genetics; D001741:Black or African American
D004247:DNA; D010741:Phospholipases A; D054467:Phospholipases A2