title: Bilateral nipple hyperkeratosis treated successfully with topical isotretinoin.
abstract: A 22-year-old woman presented with bilateral thickening and hyperpigmentation of her nipples since the age of 17 years. There was no history of pregnancy or oral contraceptive pill use. Isotretinoin 0.025% gel was applied twice daily and the lesions disappeared in 4 weeks. After the drug was ceased, recurrence appeared within 4 months. The same therapy, applied for 2 weeks, again cleared the problem.
authors.affiliation: Department of Dermatology, Faculty of Medicine, Gazi University, Ankara, Turkey.
authors.forename: P
authors.initials: P
authors.lastname: Toros
authors.forename: M
authors.initials: M
authors.lastname: Onder
authors.forename: M A
authors.initials: MA
authors.lastname: Gürer
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D005260:Female; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage*; D007642:Keratosis / Q000188:drug therapy* / Q000473:pathology; D009558:Nipples / Q000473:pathology
chemical_list: D015474:Isotretinoin