[Acute respiratory failure due to neuromuscular disorders].
Numerous acute and chronic neuromuscular disorders may induce an acute ventilatory failure. The latter is sometimes triggered by a complication like a bronchial aspiration, a pneumonia, or an atelectasis. The acute ventilatory failure often develops insidiously and may be missed until the terminal event. Four different clinical presentations are depicted in this review: slowly progressive (Duchenne muscular dystrophy), rapidly progressive (Guillain-Barré syndrome), chronic with exacerbations (myasthenia gravis), and a form consecutive to critical care (critical care polyneuropathy and myopathy). For each type of ventilatory failure, the review discusses the preventive surveillance, the treatment of acute respiratory failure, and the long-term management.
Fitting
J W
JW
Division de Pneumologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Suisse.
Chevrolet
J C
JC
D000208:Acute Disease; D020275:Guillain-Barre Syndrome / Q000150:complications; D006801:Humans; D009136:Muscular Dystrophies / Q000150:complications; D009157:Myasthenia Gravis / Q000150:complications; D009468:Neuromuscular Diseases / Q000150:complications*; D011115:Polyneuropathies / Q000150:complications; D012131:Respiratory Insufficiency / Q000209:etiology*