An efficient synthesis of two monosulfated trisaccharides with the Galbeta1,3GlcNacbeta1,3Galbeta-O-allyl backbone.
The GlcNAcbeta(1-->3) Gal linked disaccharide 7 was synthesized as key building blocks for the construction of target monosulfated trisaccharides 1 and 2 using oxazoline 3 as glycosyl donor promoted by BF3 x Et2O.
Xia
J
J
Department of Molecular & Cellular Biophysics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
Piskorz
C F
CF
Locke
R D
RD
Chandrasekaran
E V
EV
Alderfer
J L
JL
Matta
K L
KL
D002240:Carbohydrate Sequence; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D013431:Sulfates / Q000737:chemistry*
D009844:Oligosaccharides; D013431:Sulfates