[Perioperative myocardial infarct during the surgical treatment of IHD].
Perioperative myocardial infarction is one of the most frequent causes of death in patients subjected to surgery for coronary disease. Study of the pathogenesis of this complication may become an approach to decreasing the postoperative mortality. Forty-seven case histories and autopsy protocols of patients who died after surgery on the coronary arteries and 241 intraoperative biopsy specimens of autovenous shunts are analyzed. The mechanisms underlying the cardiomyocyte necrosis in surgical treatment of coronary disease are based on various pathological processes, the leading of which is thrombosis of the shunts and coronary arteries. The principal factors were intraoperative ischemia of autovein endothelium and shunting of coronary artery with a narrow distal bed.
Sheremet'eva
G F
GF
Lebedeva
R N
RN
Ivanova
A G
AG
Fishkova
Z P
ZP
Ziuliaeva
T P
TP
D000328:Adult; D000368:Aged; D001011:Aorta / Q000473:pathology; D001344:Autopsy; D001706:Biopsy; D003328:Coronary Thrombosis / Q000150:complications / Q000473:pathology / Q000601:surgery; D003331:Coronary Vessels / Q000473:pathology; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007431:Intraoperative Complications / Q000209:etiology* / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology* / Q000473:pathology; D017202:Myocardial Ischemia / Q000150:complications / Q000473:pathology / Q000601:surgery*; D009206:Myocardium / Q000473:pathology