title: [Unexpected regeneration of a congenital unilateral hypoplastic- dysplastic kidney after a contralateral nephrectomy for Wilms tumor].
abstract: The congenital hypoplastic-dysplastic kidney is characterized by a significant reduction of renal mass, an abnormal parenchymal differentiation and is associated with anomalies of the whole urinary tract. Not much is known about the ability for regeneration in such a kidney. We report on a 2 year 11 months old boy with an anaplastic Wilms tumor of the left kidney, in whom after tumor-nephrectomy an unexpected functional and sonographically documented morphological regeneration of the contralateral hypoplastic-dysplastic kidney occurred. The regeneration of this kidney is especially notable, because it occurred during nephrotoxic chemotherapy and radiotherapy.
authors.affiliation: St. Anna Kinderspital, Wien.
authors.forename: L
authors.initials: L
authors.lastname: Kager
authors.forename: B
authors.initials: B
authors.lastname: Schroth
authors.forename: G
authors.initials: G
authors.lastname: Amann
authors.forename: A
authors.initials: A
authors.lastname: Zoubek
authors.forename: P
authors.initials: P
authors.lastname: Wiesbauer
authors.forename: E
authors.initials: E
authors.lastname: Horcher
authors.forename: K
authors.initials: K
authors.lastname: Dieckmann
authors.forename: H
authors.initials: H
authors.lastname: Gadner
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D006801:Humans; D007668:Kidney / Q000002:abnormalities* / Q000187:drug effects / Q000502:physiology* / Q000601:surgery; D007677:Kidney Function Tests; D007680:Kidney Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D008297:Male; D009392:Nephrectomy; D020127:Recovery of Function; D012038:Regeneration / Q000187:drug effects / Q000502:physiology* / Q000528:radiation effects; D016896:Treatment Outcome; D009396:Wilms Tumor / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery