title: [Cerebral infarction associated with mobile thoracic ascending aortic thrombus in a patient with essential thrombocythemia].
abstract: A 77-year-old man with essential thrombocythemia had embolic stroke associated with mobile thoracic ascending aortic thrombus despite of receiving antiplatelet drug. He had history of toe ulcer and ileus within previous 2 years. He was diagnosed as essential thrombocythemia and received antiplatelet drug. He had consciousness disturbance and admitted to our hospital. Cerebral angiography disclosed emboli in the right middle cerebral artery (M2). Transesophageal echocardiography showed evidence of a mobile thrombus attached to the wall of the ascending aorta at the first day. The thrombus was no longer present after treatment with heparin followed by no recurrent embolic event. We prescribed hydroxyurea for essential thrombocythemia for chronic phase treatment. We consider that with essential thrombocythemia the thrombus of the ascending aorta caused the cerebral infarction. And we succeeded of the treatment of the embolic stroke and prevalence of the emboli with essential thrombocythemia.
authors.affiliation: Department of Strokology, Kumamoto City Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Hino
authors.forename: T
authors.initials: T
authors.lastname: Terasaki
authors.forename: Y
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Y
authors.initials: Y
authors.lastname: Hara
authors.forename: M
authors.initials: M
authors.lastname: Uchino
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D001011:Aorta; D002544:Cerebral Infarction / Q000188:drug therapy / Q000209:etiology*; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D013920:Thrombocythemia, Essential / Q000150:complications*; D013927:Thrombosis / Q000150:complications* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006493:Heparin