Oligosaccharides in human milk during different phases of lactation.
Twenty-one oligosaccharides of human milk were quantified by high-performance anion-exchange chromatography. Milk samples were collected from 18 mothers during the first 3 mo of lactation. The data show that the highest amount of all oligosaccharides is present at day 4 postpartum (20 g l(-1)) and then decreases by about 20% at day 30 of lactation. The protective role played by these substances against different infectious agents, in different organs and systems of the breastfed baby, is emphasized.
Coppa
G V
GV
Department of Pediatrics, University of Ancona, Italy.
Pierani
P
P
Zampini
L
L
Carloni
I
I
Carlucci
A
A
Gabrielli
O
O
D000328:Adult; D002851:Chromatography, High Pressure Liquid; D002852:Chromatography, Ion Exchange; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007774:Lactation; D008137:Longitudinal Studies; D008895:Milk, Human / Q000737:chemistry*; D009844:Oligosaccharides / Q000032:analysis*; D049590:Postpartum Period; D012680:Sensitivity and Specificity; D013997:Time Factors
D009844:Oligosaccharides