Macroamylasaemia--a prognostic marker in a syndrome of malabsorption and complete villous atrophy? An uncommon clinical condition.
We report a rare case of chronic persistent hyperamylasaemia secondary to macroamylasaemia in association with coeliac disease in a 56-year-old woman. Her symptoms, including macroamylasaemia, ebbed away following commencement of a gluten free diet. Only four cases of a similar nature have been described in the literature. The differential diagnosis of macroamylasaemia should include coeliac disease, and an awareness of this association might obviate a variety of unnecessary diagnostic investigations.
Viswanath
S
S
Royal Victoria Infirmary, Newcastle upon Tyne, UK. viswa1@hotmail.com
Wynne
K
K
D000681:Amylases / Q000097:blood*; D015415:Biomarkers / Q000097:blood*; D001706:Biopsy; D002446:Celiac Disease / Q000097:blood* / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D004386:Duodenum / Q000473:pathology; D005260:Female; D006801:Humans; D046911:Macromolecular Substances; D008875:Middle Aged; D011379:Prognosis
D015415:Biomarkers; D046911:Macromolecular Substances; D000681:Amylases; C001663:macroamylase