[Proton magnetic resonance study of the changes in blood lipids in malignant and benign neoplasms].
High-resolution 1H-NMR spectrometry (360 MHz) was used in combination with thin layer chromatography to study changes in composition and molecular structure of inverted micelles of blood lipids from patients with breast and uterus cancer. Changes in relative intensity of NMR signals of lipids compared with norm were revealed. The changes in the lipid composition of blood components, in particular, in cholesterol content, determine the differences in structure and molecular mobility of these lipids, which probably explains the regularities observed in the NMR spectra.
Katrikadze
N G
NG
Tbilisi State University, Georgia.
Tsarpidze
M A
MA
Dzhishkariani
O S
OS
Sibel'dina
L A
LA
Bochorishvili
I A
IA
D001943:Breast Neoplasms / Q000097:blood* / Q000145:classification; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D009682:Magnetic Resonance Spectroscopy; D008823:Micelles; D011522:Protons; D014594:Uterine Neoplasms / Q000097:blood* / Q000145:classification
D008055:Lipids; D008823:Micelles; D011522:Protons