title: Preparation and characteristics of rumen-bypass microcapsules for improvement of productivity in ruminants.
abstract: Rumen-bypass microcapsules were prepared by a spray-dry method for protection against microbial hydrogenation in the rumen (neutral pH). Porous starch was used as the core material, and the microcapsules were prepared by a triple coating of Eudragit E100, AS-HF, and shellac. Capsules were generated with yield of about 48% and a mean particle diameter of 20-30 microm. The microcapsules had high stability in a neutral solution that mimicked a ruminal pH (pH 6.5). Moreover, when microcapsules were incubated in the presence of ruminal microorganisms, about 65% of the microcapsules were resistant to digestion in ruminal fluids, and protection of the inclusion substance was observed. In addition, the efficiency of release of these microcapsules was about 85% within only 30 min in the abomasal environment (pH 3.0).
authors.affiliation: Department of Food Science and Technology, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yoshimaru
authors.forename: M
authors.initials: M
authors.lastname: Shibata
authors.forename: T
authors.initials: T
authors.lastname: Fukugomori
authors.forename: K
authors.initials: K
authors.lastname: Matsumoto
mesh_terms: D000818:Animals; D002214:Capsules; D002417:Cattle; D010450:Endopeptidases / Q000008:administration & dosage / Q000494:pharmacology; D005079:Excipients; D006863:Hydrogen-Ion Concentration; D012417:Rumen / Q000201:enzymology / Q000502:physiology*
chemical_list: D002214:Capsules; D005079:Excipients; D010450:Endopeptidases