[Isoenzymes of gammaglutamyltransferase in patients with obstructive and hepatocellular icterus].
We have been determining the GGT IE isoenzyme in patients with hepatitis A and B with decomposed liver cirrhosis, with obstructive hepatitis caused by the gall stones. In patients with hepatitis A and B the IE is located between albumin and betaglobulin, as well as in patients with obstructive hepatitis caused by the gall stones; in the latter partly between Alpha 1 and Alpha 2 globulin. In patients with decompensated liver cirrhosis (37.7% of the patients) there was IE activity 100% in Alpha 2 globulin area; in 6.25% of patients the activity was in the prealbumin area. In patients with secondary liver tumors we got a rather high increase of the GGT IE activity in Alpha 1 globulin area, in 77.7% of the patients even 80 to 100%. In some patients with disease progression we noticed the GGT IE activity in Beta globulin area. The results in primary liver malignomas were different. In 68.5% of the patients the GGT IE activity dominated in Alpha 1 globulin area.
Anic
K
K
Klinik für Innere Krankheiten, Osijek, Kroatien.
Ivandic
A
A
Peric
L
L
Fijacko
M
M
Volaric
M
M
Bacun
T
T
Kovacic
D
D
Getto
L
L
D001650:Bile Duct Neoplasms / Q000201:enzymology*; D018450:Disease Progression; D005260:Female; D006525:Hepatitis, Viral, Human / Q000201:enzymology*; D006801:Humans; D007527:Isoenzymes; D008105:Liver Cirrhosis, Biliary / Q000201:enzymology*; D008113:Liver Neoplasms / Q000201:enzymology* / Q000556:secondary; D008297:Male; D005723:gamma-Glutamyltransferase / Q000097:blood* / Q000378:metabolism*
D007527:Isoenzymes; D005723:gamma-Glutamyltransferase