A possible solution to the paradox of the "lupus anticoagulant": antiphospholipid antibodies accelerate thrombin generation by inhibiting annexin-V.
Rand
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JH
Wu
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Giesen
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D017304:Annexin A5 / Q000037:antagonists & inhibitors / Q000378:metabolism*; D017152:Antibodies, Antiphospholipid / Q000276:immunology / Q000378:metabolism*; D016736:Antiphospholipid Syndrome / Q000276:immunology / Q000378:metabolism; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000276:immunology*; D013917:Thrombin / Q000096:biosynthesis* / Q000276:immunology
D017304:Annexin A5; D017152:Antibodies, Antiphospholipid; D016682:Lupus Coagulation Inhibitor; D013917:Thrombin