title: Antimicrobial activity of some N-alkyl and N-nitrobenzyl substituted halides of (E)-4'-hydroxy-3'-methoxystilbazoles-4.
abstract: The synthesis of 11 new N-substituted derivatives of (E)-4'-hydroxy-3'-methoxystilbazoles-4 and their antimicrobial activity are reported. The relationships between structure and antibacterial activity are studied. In particular, compounds 5, 7 and 8 showed good antibacterial activity against Staphylococcus aureus, Streptococcus faecalis and Bacillus subtilis, while compound 6 did so against S. aureus and S. faecalis.
authors.affiliation: Faculty of Chemistry, Adam Mickiewicz University, Poznań, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Prukała
authors.forename: B
authors.initials: B
authors.lastname: Kedzia
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects; D013293:Enterococcus faecalis / Q000187:drug effects; D006219:Halogens / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D011725:Pyridines / Q000737:chemistry / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D006219:Halogens; D011725:Pyridines