title: Suicidality and substance misuse in first-admitted subjects with psychotic disorder.
abstract: OBJECTIVE
  The aim of this study was to examine the links between suicidality and substance misuse (abuse or dependence) in subjects with early psychosis.
  
  
  METHODS
  Data were collected on a sample of first-admitted subjects with psychosis (n=64).
  
  
  RESULTS
  More than 1 in 4 patients had a history of parasuicide, and more than 1 in 10 patients were referred to the psychiatric hospital after such an act. Parasuicide was more frequent in subjects with a history of drug misuse (OR=4, 95% CI= 1.1-14.0, P=0.03), and especially of polysubstance use (OR=6.6, 95% CI=1.2-34.7, P=0.03).
  
  
  CONCLUSIONS
  The association between substance misuse and suicidality found in subjects with psychosis is similar to that which exists in the general population. Since early psychosis is a high-risk period for substance misuse, subjects with incipient psychosis may be especially vulnerable to the devastating consequences of drug use with regard to increased risk of suicide.
authors.affiliation: Department of Psychiatry, University Victor Segalen, Bordeaux, France.
authors.forename: H
authors.initials: H
authors.lastname: Verdoux
authors.forename: F
authors.initials: F
authors.lastname: Liraud
authors.forename: B
authors.initials: B
authors.lastname: Gonzales
authors.forename: F
authors.initials: F
authors.lastname: Assens
authors.forename: F
authors.initials: F
authors.lastname: Abalan
authors.forename: J
authors.initials: J
authors.lastname: van Os
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006760:Hospitalization; D006778:Hospitals, Psychiatric; D006801:Humans; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000523:psychology* / Q000534:rehabilitation*; D019966:Substance-Related Disorders / Q000523:psychology*; D013405:Suicide / Q000523:psychology*