title: Low-grade fibrosarcoma with palisaded granulomalike bodies (giant rosettes): report of a case that metastasized.
abstract: "Hyalinizing spindle cell tumor with giant rosettes" is a tumor recently described by Lane et al. and thought by them possibly to represent a form of low-grade fibromyxoid sarcoma. Proof of a metastatic potential was lacking. We report an example of this tumor on the arm of a 28-year-old woman. The ultrastructural study of the tumor confirmed the fibroblastic nature of the lesion, which subsequently metastasized to the lung. Histologically, the giant rosettes simulated palisaded granulomas. Our findings warrant classifying the tumor as a sarcoma, and we suggest the designation low-grade fibrosarcoma with palisaded granulomalike bodies (giant rosettes).
authors.affiliation: Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Woodruff
authors.forename: C R
authors.initials: CR
authors.lastname: Antonescu
authors.forename: R A
authors.initials: RA
authors.lastname: Erlandson
authors.forename: P J
authors.initials: PJ
authors.lastname: Boland
mesh_terms: D000328:Adult; D001132:Arm; D005260:Female; D005354:Fibrosarcoma / Q000473:pathology* / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000556:secondary*; D012983:Soft Tissue Neoplasms / Q000473:pathology*