The determination of cardioventilatory coupling from heart rate and ventilatory time series.
In 35 anaesthetised human subjects, we examined the effect of cardioventilatory coupling on R-R interval and ventilatory period time series. We observed that, in the presence of coupling: (a) ventilatory period fluctuated in a quantal manner, each quantal step corresponding to a multiple (or a little less) of the heart period; (b) heart period fluctuations, associated with respiratory sinus arrythmia, were identical for consecutive ventilatory periods. The regularity of heart period variation lead to geometric patterning of raw R-R time series, R-R consecutive difference time series, the phase portrait (R-R(n) vs R-R(n+1)) and the map of R-R interval variation (DeltaR-R(n) vs DeltaR-R(n+1)). These geometric features may be useful for the determination of cardioventilatory coupling from heart rate time series.
Galletly
D C
DC
Wellington School of Medicine, P.O. Box 7343, Wellington, New Zealand. surgdg@wnmeds.ac.nz
Larsen
P D
PD
D000328:Adult; D005260:Female; D006321:Heart / Q000502:physiology*; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D012122:Ventilators, Mechanical