Calcitonin treatment in osteoectasia with hyperphosphatasia (juvenile Paget's disease): radiographic changes after treatment.
Osteoectasia with hyperphosphatasia is a rare skeletal disorder, characterised by demineralisation and expansion of tubular bones and elevated serum alkaline phosphatase. We present a girl diagnosed as having osteoectasia with hyperphosphatasia who had swelling of phalanges of both hands and motor retardation. She was treated with synthetic human calcitonin. Clinical and radiological findings showed remarkable improvement after 2 years' treatment.
Tüysüz
B
B
Division of Genetics and Teratology, Department of Paediatrics, Cerrahpaşa Faculty of Medicine, University of Istanbul, Istanbul, Turkey.
Mercimek
S
S
Ungür
S
S
Deniz
M
M
D000135:Acid Phosphatase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002116:Calcitonin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007223:Infant; D010001:Osteitis Deformans / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D011859:Radiography
D002116:Calcitonin; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase