title: Determination of in vivo rat muscle Gd-DTPA relaxivity at 6.3 T.
abstract: For the in vivo relaxivity of Gd-DTPA at 6.3 T in rat muscle a value of 2.7+/-0.5 (mM s)(-1) was found, and for the in vitro value in water 3.00+/-0.56 (mM s)(-1) at 37 degrees C. The temperature dependence of the in vitro relaxivity was -0.087 (mM s degrees C)(-1). The relation between 1/T1 and the tissue Gd-DTPA concentration is linear for the normally used in vivo Gd-DTPA concentration range.
authors.affiliation: Department of Applied Physics, Delft University of Technology, The Netherlands.
authors.forename: T H
authors.initials: TH
authors.lastname: Rozijn
authors.forename: B P
authors.initials: BP
authors.lastname: van der Sanden
authors.forename: A
authors.initials: A
authors.lastname: Heerschap
authors.forename: J H
authors.initials: JH
authors.lastname: Creyghton
authors.forename: W M
authors.initials: WM
authors.lastname: Boveé
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000493:pharmacokinetics*; D005069:Evaluation Studies as Topic; D019786:Gadolinium DTPA / Q000493:pharmacokinetics*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D018482:Muscle, Skeletal / Q000033:anatomy & histology / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D013696:Temperature
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA