Prion replication-once again blaming the dendritic cell.
The lymphoid system is known to be involved in the propagation and spread of scrapie. However, the identity of the cell type responsible for scrapie replication remains controversial. A new study provides evidence that the follicular dendritic cells in the spleen are the targets of this infectious form of prion (pages 1308-1312).
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D000818:Animals; D003713:Dendritic Cells / Q000276:immunology*; D051379:Mice; D011328:Prions / Q000502:physiology*; D012608:Scrapie / Q000276:immunology* / Q000635:transmission
D011328:Prions