[A case of intra-arterial infusion chemotherapy for liver metastases of breast cancer].
A 55-year-old woman was seen in our clinic for liver metastases of breast cancer. She underwent a standard radical mastectomy in June, 1987. Five years and 3 months after the operation, multiple bone metastases were found on bone scintigram and 10 years after the operation multiple liver metastases on CT. She was treated with a combination of intra-arterial chemotherapy using 20-30 mg/body epirubicin every 2 weeks and chemo-endocrine therapy using medroxyprogesterone acetrate (MPA) 600 mg/day + 5'-DFUR 600 mg/day. The treatment seemed to be very useful. The liver metastases regressed by 99% in size, and the duration of response was 9 months. Bone metastases did not progress from the treatment.
Yasui
M
M
Dept. of Surgery, Kaizuka City Hospital.
Yayoi
E
E
Nishi
T
T
Yamasaki
M
M
Kishibuchi
M
M
Yagyu
T
T
Kawasaki
K
K
D000284:Administration, Oral; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000473:pathology*; D002291:Carcinoma, Papillary / Q000188:drug therapy* / Q000556:secondary*; D004334:Drug Administration Schedule; D015251:Epirubicin / Q000008:administration & dosage; D005260:Female; D005467:Floxuridine / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008525:Medroxyprogesterone / Q000008:administration & dosage; D008875:Middle Aged
D005467:Floxuridine; D015251:Epirubicin; D008525:Medroxyprogesterone; C025034:doxifluridine