title: [Five cases of cerebral and/or cerebellar embolism after insertion of a heparin-coated catheter from the left thoracoacromial artery].
abstract: We reported five cases of cerebral and/or cerebellar embolism after insertion of a heparin-coated catheter from the left thoracoacromial artery for multiple liver metastases. They were one patient with multiple liver metastases from the angiosarcoma of the scalp, and 4 others with gastrointestinal cancer liver metastases. The first case suffered a cerebeller embolism just after removal of a catheter that had been obstructed. In this case, it is possible that the thrombus quickly migrated into a cranial vessel from around the catheter. In the others with patent catheters, the cerebral embolisms occurred more than a month after insertion of the catheters. In the latter cases, it is thought that embolisms did not occur because of catheter insertion maneuver. However, a thrombus that grew around the catheter migrated into the left common carotid artery or the left vertebral artery. The anti-coagulation therapy should be considered for prophylactic treatment.
authors.affiliation: First Dept. of Surgery, Kyoto Prefecture University of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Koh
authors.forename: H
authors.initials: H
authors.lastname: Taniguchi
authors.forename: S
authors.initials: S
authors.lastname: Kunishima
authors.forename: A
authors.initials: A
authors.lastname: Yamaguchi
authors.forename: T
authors.initials: T
authors.lastname: Ohbayashi
authors.forename: K
authors.initials: K
authors.lastname: Kitagawa
authors.forename: T
authors.initials: T
authors.lastname: Yamaki
authors.forename: H
authors.initials: H
authors.lastname: Yamagishi
mesh_terms: D000368:Aged; D002404:Catheterization / Q000295:instrumentation; D002526:Cerebellar Diseases / Q000209:etiology*; D006493:Heparin; D006801:Humans; D015918:Infusion Pumps, Implantable / Q000009:adverse effects*; D007261:Infusions, Intra-Arterial; D020766:Intracranial Embolism / Q000209:etiology*; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology
chemical_list: D006493:Heparin