title: Ecthyma gangrenosum as a very early herald of acute lymphoblastic leukaemia.
abstract: Ecthyma gangrenosum is a manifestation of cutaneous infection by Pseudomonas aeruginosa. The lesion may be associated with immunocompromise, in particular neutropenia. We present a case of ecthyma gangrenosum in a previously healthy child who 3 months later developed acute lymphoblastic leukaemia; we use this to illustrate the lack of information on the growth rate of malignant and premalignant leukaemic cells in children.
authors.affiliation: Department of Paediatrics, Ealing Hospital NHS Trust, Middlesex, UK.
authors.forename: A
authors.initials: A
authors.lastname: Pouryousefi
authors.forename: J
authors.initials: J
authors.lastname: Foland
authors.forename: C
authors.initials: C
authors.lastname: Michie
authors.forename: M
authors.initials: M
authors.lastname: Cummins
mesh_terms: D000912:Antibodies, Neoplasm; D015703:Antigens, CD / Q000276:immunology; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D002675:Child, Preschool; D004473:Ecthyma / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D011552:Pseudomonas Infections / Q000150:complications; D017192:Skin Diseases, Bacterial / Q000382:microbiology; D013997:Time Factors
chemical_list: D000912:Antibodies, Neoplasm; D015703:Antigens, CD