Clinical use of lipids to control inflammatory disease.
Selective dietary supplementation with lipids has long been used to influence the course of chronic inflammatory diseases. This review describes new aspects of the molecular mechanism of lipids to modulate leukocyte activity and highlights some recent clinical studies on therapeutic lipid administration. New promising advances in parenteral application of lipids as well as the impact on acute inflammatory disorders are discussed.
Mayer
K
K
Department of Internal Medicine, Justus Liebig University Giessen, Germany.
Seeger
W
W
Grimminger
F
F
D000818:Animals; D000893:Anti-Inflammatory Agents; D001172:Arthritis, Rheumatoid / Q000628:therapy; D019587:Dietary Supplements; D006801:Humans; D007249:Inflammation / Q000503:physiopathology / Q000628:therapy*; D015212:Inflammatory Bowel Diseases / Q000628:therapy; D008055:Lipids / Q000627:therapeutic use*; D011565:Psoriasis / Q000628:therapy; D018805:Sepsis / Q000628:therapy
D000893:Anti-Inflammatory Agents; D008055:Lipids