title: Prion replication-once again blaming the dendritic cell.
abstract: The lymphoid system is known to be involved in the propagation and spread of scrapie. However, the identity of the cell type responsible for scrapie replication remains controversial. A new study provides evidence that the follicular dendritic cells in the spleen are the targets of this infectious form of prion (pages 1308-1312).
authors.forename: M S
authors.initials: MS
authors.lastname: Sy
authors.forename: P
authors.initials: P
authors.lastname: Gambetti
mesh_terms: D000818:Animals; D003713:Dendritic Cells / Q000276:immunology*; D051379:Mice; D011328:Prions / Q000502:physiology*; D012608:Scrapie / Q000276:immunology* / Q000635:transmission
chemical_list: D011328:Prions