title: 1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis.
authors.affiliation: NMR Research Group, A.I.Virtanen Institute for Molecular Sciences, University of Kuopio, FIN-70211 Kuopio, Finland.
authors.forename: J M
authors.initials: JM
authors.lastname: Hakumäki
authors.forename: H
authors.initials: H
authors.lastname: Poptani
authors.forename: A M
authors.initials: AM
authors.lastname: Sandmair
authors.forename: S
authors.initials: S
authors.lastname: Ylä-Herttuala
authors.forename: R A
authors.initials: RA
authors.lastname: Kauppinen
mesh_terms: D017209:Apoptosis / Q000187:drug effects; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology / Q000628:therapy* / Q000648:ultrastructure; D005231:Fatty Acids, Unsaturated / Q000378:metabolism*; D015774:Ganciclovir / Q000494:pharmacology / Q000627:therapeutic use; D015316:Genetic Therapy; D005910:Glioma / Q000378:metabolism / Q000473:pathology / Q000628:therapy* / Q000648:ultrastructure; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008854:Microscopy, Electron; D011522:Protons
chemical_list: D005231:Fatty Acids, Unsaturated; D011522:Protons; D015774:Ganciclovir