[Adiabatic solution for the Ohmic cable equation. An homogeneous cell, prospects for electronic measurements].
Exact and adiabatic electrotonic solutions [1] were calculated for reconstructed motoneurone and hippocampal interneurone in case of linear and exponential ramp stimulation by the fixed current, potential or homogenous electric field. For the rising exponential ramp the solutions are identical. In case of the decaying exponent the adiabatic solution becomes an asymptote for the exact one if the stimulus decays slower than relaxation of the initial conditions in the cell. If the stimulus decays faster, the asymptote is the current or potential axis, depending on the stimulation mode. For electrotonically short cell, the exact solution approaches the asymptote faster. The solution for the exponentially rising field does not depend on the dendritic tree configuration and depends only on the effective electrotonic length of the neurone. It could be useful to apply ramp stimulation, especially exponential ramp of the electric field, to estimate electrotonic parameters of cells.
Alaburda
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Institute for Biomedical Research, Kaunas Medical Academy, Lithuania.
Baginskas
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Gutman
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Svirskis
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D004560:Electricity; D008962:Models, Theoretical; D013816:Thermodynamics