title: Haplotype frequencies of eight Y-chromosome STR loci in Barcelona (North-East Spain).
abstract: Haplotype frequencies for eight Y-chromosomal short tandem repeat (STR) loci were determined in paragraph signa population sample from Barcelona (NE Spain). After PCR amplification and denaturing PAGE electrophoresis, DYS19, DYS388, DYS389 I/II, DYS390, DYS391, DYS392 and DYS393 loci were typed. Complete eight paragraph signY-chromosomal STRs haplotypes could be formed for 223 subjects, among which 137 different haplotypes were observed. The most common haplotype was shared by 13% of the sample, while 108 haplotypes were unique. The discrimination capacity was 61.5% and the gene diversity was 0.978. From the forensic point of view the combined polymorphisms provide a high diagnostic efficiency.
authors.affiliation: Forensic Genetics Laboratory, Department of Legal Medicine, Faculty of Medicine, University of Barcelona, C. Casanova 143, E-08036 Barcelona, Spain. mgene@medicina.ub.es
authors.forename: M
authors.initials: M
authors.lastname: Gené
authors.forename: N
authors.initials: N
authors.lastname: Borrego
authors.forename: A
authors.initials: A
authors.lastname: Xifró
authors.forename: E
authors.initials: E
authors.lastname: Piqué
authors.forename: P
authors.initials: P
authors.lastname: Moreno
authors.forename: E
authors.initials: E
authors.lastname: Huguet
mesh_terms: D001483:Base Sequence; D002874:Chromosome Mapping; D004247:DNA / Q000302:isolation & purification; D019992:Databases as Topic; D005554:Forensic Medicine; D014644:Genetic Variation; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D013030:Spain; D020080:Tandem Repeat Sequences; D014998:Y Chromosome / Q000235:genetics*
chemical_list: D004247:DNA