title: New scalaranes from the nudibranch Glossodoris atromarginata and its sponge prey.
abstract: Two new scalaranes (1 and 2) have been isolated from the dorid nudibranch Glossodoris atromarginataand its prey. The structures were deteremined by spectral techniques and confirmed by chemical methods. Compounds 1 and 3 showed selective cytotoxic activity against human thyroid carcinoma.
authors.affiliation: Istituto per la Chimica di Molecole di Interesse Biologico (ICMIB)(1) del CNR, Via Toiano 6, 80072 Arco Felice, Napoli, Italy. font@trinc.icmib.na.cnr.it
authors.forename: A
authors.initials: A
authors.lastname: Fontana
authors.forename: P
authors.initials: P
authors.lastname: Cavaliere
authors.forename: N
authors.initials: N
authors.lastname: Ungur
authors.forename: L
authors.initials: L
authors.lastname: D'Souza
authors.forename: P S
authors.initials: PS
authors.lastname: Parameswaram
authors.forename: G
authors.initials: G
authors.lastname: Cimino
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D015394:Molecular Structure; D008974:Mollusca / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013964:Thyroid Neoplasms / Q000473:pathology; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D012717:Sesquiterpenes