Modulation of inflammation and immunity by arginine supplements.
Arginine holds a key position in the cellular functions and interactions that occur during inflammation and immune responses. The competition for arginine as a substrate between nitric oxide synthase and arginase appears to be at the core of the regulation of the inflammatory process. This review examines some of the recently defined effects of arginine on various inflammatory processes and immune cell functions.
Efron
D T
DT
Department of Surgery, Sinai Hospital of Baltimore, MD 21215, USA.
Barbul
A
A
D000818:Animals; D001120:Arginine / Q000276:immunology / Q000502:physiology*; D019587:Dietary Supplements; D006801:Humans; D007113:Immunity, Innate / Q000502:physiology*; D007249:Inflammation / Q000276:immunology*; D009569:Nitric Oxide / Q000502:physiology; D019001:Nitric Oxide Synthase / Q000502:physiology*; D014945:Wound Healing / Q000502:physiology
D009569:Nitric Oxide; D001120:Arginine; D019001:Nitric Oxide Synthase