Stimulation of lipolysis by pycnogenol.
We studied the influence of pycnogenol on the lipolysis of 3T3 L1 cells after differentiation. When pycnogenol or epinephrine was exposed to mature adipocytes, the smaller (less than 20 microm(2)) intracytoplasmic lipid droplets selectively disappeared. These data suggest that pycnogenol stimulates lipolysis.
Hasegawa
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Department of Food and Nutrition, Nagoya Bunri College, Nagoya, Japan. hsgwn@nagoya-bunri.ac.jp
D016475:3T3 Cells; D017667:Adipocytes / Q000187:drug effects* / Q000378:metabolism; D000818:Animals; D005419:Flavonoids / Q000494:pharmacology*; D007328:Insulin / Q000378:metabolism; D008066:Lipolysis / Q000187:drug effects*; D051379:Mice; D010936:Plant Extracts
D005419:Flavonoids; D007328:Insulin; D010936:Plant Extracts; C024070:pycnogenols