Bilateral nipple hyperkeratosis treated successfully with topical isotretinoin.
A 22-year-old woman presented with bilateral thickening and hyperpigmentation of her nipples since the age of 17 years. There was no history of pregnancy or oral contraceptive pill use. Isotretinoin 0.025% gel was applied twice daily and the lesions disappeared in 4 weeks. After the drug was ceased, recurrence appeared within 4 months. The same therapy, applied for 2 weeks, again cleared the problem.
Toros
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P
Department of Dermatology, Faculty of Medicine, Gazi University, Ankara, Turkey.
Onder
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M
Gürer
M A
MA
D000279:Administration, Cutaneous; D000328:Adult; D005260:Female; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage*; D007642:Keratosis / Q000188:drug therapy* / Q000473:pathology; D009558:Nipples / Q000473:pathology
D015474:Isotretinoin