[Orexins and orexin receptors].
The hypothalamus plays a central role in the integrated control of feeding and energy homeostasis. Two novel neuropeptides Orexin -A and -B were identified. Orexins activate two closely related G protein-coupled receptors and stimulate food consumption. They act also as mediators in the central feedback mechanism and regulates feeding behavior.
Kotaska
K
K
Ustav klinické biochemie a patobiochemie 2. LF UK, Praha.
Průsa
R
R
D000818:Animals; D002352:Carrier Proteins / Q000737:chemistry / Q000502:physiology*; D005247:Feeding Behavior / Q000502:physiology; D006801:Humans; D007031:Hypothalamus / Q000502:physiology; D047908:Intracellular Signaling Peptides and Proteins; D009479:Neuropeptides / Q000737:chemistry / Q000502:physiology*; D064446:Orexin Receptors; D000068797:Orexins; D043562:Receptors, G-Protein-Coupled; D018013:Receptors, Neuropeptide / Q000502:physiology*
D002352:Carrier Proteins; C000596229:HCRT protein, human; D047908:Intracellular Signaling Peptides and Proteins; D009479:Neuropeptides; D064446:Orexin Receptors; D000068797:Orexins; D043562:Receptors, G-Protein-Coupled; D018013:Receptors, Neuropeptide