Axial length increase in lid-sutured rabbits.
Using eyelid sutures, we induced axial elongation in 20 15-day-old rabbits. When the eyelid sutures were opened, the eyes revealed a slight increase in their axial length. This evident axial elongation continued to evolve despite restitution of functional integrity to the previously sutured eyes. We suspect that because the lid sutures altered visual input and inhibited the retina from maintaining control of ocular growth, the retina instigated excessive eye growth, resulting in the initial consequent axial elongation that was evident on removal of the sutures. Additionally, poor quality of the retinal image, probably resulting from the noncorrected myopic ametropia caused by the lid sutures, could be the cause of the continued axial length increase observed after the lid sutures were removed.
Verolino
M
M
Istituto di Clinica Oculistica, Facoltà di Medicina, II Università degli Studi di Napoli, Italy.
Nastri
G
G
Sellitti
L
L
Costagliola
C
C
D000818:Animals; D005123:Eye / Q000254:growth & development / Q000473:pathology*; D005143:Eyelids / Q000601:surgery*; D005260:Female; D008297:Male; D011817:Rabbits; D012683:Sensory Deprivation / Q000502:physiology; D013537:Sutures