title: [Recent clinical trials for sepsis: analysis of the results and future perspectives].
abstract: Recent clinical trials with experimental immunotherapeutic agents for sepsis have not proven their overall benefit yet although some studies suggested significant effect of these antisepsis therapies. This review article summarizes the results of these trials, their analysis, lessons learned from past failure, and future perspectives for immunotherapies as anti-sepsis treatments.
authors.affiliation: Department of Surgery, Keio University School of Medicine, Tokyo, Japan.
authors.forename: G
authors.initials: G
authors.lastname: Wakabayashi
authors.forename: M
authors.initials: M
authors.lastname: Shimazu
authors.forename: M
authors.initials: M
authors.lastname: Tanabe
authors.forename: M
authors.initials: M
authors.lastname: Ueda
authors.forename: K
authors.initials: K
authors.lastname: Hoshino
authors.forename: Y
authors.initials: Y
authors.lastname: Morikawa
authors.forename: M
authors.initials: M
authors.lastname: Kitajima
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000032:analysis; D002986:Clinical Trials as Topic / Q000639:trends; D016207:Cytokines / Q000032:analysis; D005544:Forecasting; D006801:Humans; D012772:Shock, Septic / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D015415:Biomarkers; D016207:Cytokines