Siderophore production of Vibrio parahaemolyticus strains from different sources.
Vibrio parahaemolyticus strains isolated from different sources were assayed for their ability to produce a siderophore, vibrioferrin, under iron-limited growth conditions. The mean value +/- standard error of mean (microM vibrioferrin in spent culture supernatant/optical density at 660 nm) was 832.3 +/- 66.9 for clinical isolates (n=44), which was significantly higher (P<0.01) than those for food isolates (461.0 +/- 66.5; n=37) and coastal isolates (378.8 +/- 37.2; n=26). This suggests that greater productivity of vibrioferrin by clinical isolates may be associated with a selective advantage for survival and proliferation under conditions of iron-limitation such as in the intestine [corrected].
Yamamoto
S
S
Faculty of Pharmaceutical Sciences, Okayama University, Japan.
Okujo
N
N
Miyoshi
S
S
Shinoda
S
S
Narimatsu
S
S
D002951:Citrates / Q000138:chemical synthesis*; D003470:Culture Media; D004783:Environmental Microbiology; D005290:Ferric Compounds / Q000378:metabolism; D005516:Food Microbiology; D006801:Humans; D011760:Pyrrolidinones / Q000138:chemical synthesis*; D017262:Siderophores / Q000096:biosynthesis*; D014735:Vibrio Infections / Q000382:microbiology; D014736:Vibrio parahaemolyticus / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism*
D002951:Citrates; D003470:Culture Media; D005290:Ferric Compounds; D011760:Pyrrolidinones; D017262:Siderophores; C090126:vibrioferrin