title: Pilot study in humans on the pharmacokinetics and safety of propofol 6% SAZN.
abstract: In a pilot study on the first application of Propofol 6% SAZN in humans, the pharmacokinetics and safety of the new product seem to be similar to those of Propofol 1% SAZN and Diprivan-10 after bolus injection. The results will have to be confirmed in a larger clinical study in order to develop Propofol 6% SAZN as an alternative for Diprivan-10.
authors.affiliation: Department of Clinical Pharmacy, St. Antonius Hospital, Nieuwegein, The Netherlands.
authors.forename: C A
authors.initials: CA
authors.lastname: Knibbe
authors.forename: V S
authors.initials: VS
authors.lastname: Koster
authors.forename: L P
authors.initials: LP
authors.lastname: Aarts
authors.forename: H J
authors.initials: HJ
authors.lastname: Langemeijer
authors.forename: M
authors.initials: M
authors.lastname: Danhof
mesh_terms: D000328:Adult; D018686:Anesthetics, Intravenous / Q000009:adverse effects / Q000493:pharmacokinetics; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008875:Middle Aged; D010865:Pilot Projects; D015742:Propofol / Q000009:adverse effects* / Q000097:blood / Q000493:pharmacokinetics*; D013997:Time Factors
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol