title: Endosaccular thrombosis of cerebral aneurysms: strategy, indications, and technique.
abstract: Endovascular occlusion of a cerebral aneurysm refers to the induction of thrombosis within the aneurysm by any of several methods, all of which make use of devices delivered through the bloodstream of the parent vessel. The type of endovascular treatment most commonly used today for aneurysm treatment is the detachable platinum microcoil designed by Guglielmi, known as the GDC. The GDC has been used more frequently and successfully over the last decade as a treatment alternative to microneurosurgical clip ligation. A continual and rapid technological evolution and increasing clinical experience of neurosurgeons and neuroradiologists using this technology have been important contributors to its success. Endovascular coil embolization may hold advantages over microneurosurgical clip ligation under selected clinical circumstances. It is also necessary to acknowledge and outline the disadvantages of this form of treatment in an unbiased manner.
authors.affiliation: Division of Cerebrovascular Surgery and Interventional Neuroradiology, Department of Neurosurgery, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Thomas
authors.forename: R A
authors.initials: RA
authors.lastname: Armonda
authors.forename: R H
authors.initials: RH
authors.lastname: Rosenwasser
mesh_terms: D002533:Cerebral Angiography; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy*; D010560:Personnel Selection; D015912:Thrombolytic Therapy / Q000009:adverse effects / Q000379:methods; D016896:Treatment Outcome