Remission of juvenile rheumatoid arthritis after infection with parvovirus B19.
A 22-year-old Caucasian woman with a 6 year history of persistently active, systemic onset juvenile rheumatoid arthritis (JRA) developed symptoms of headache, dry cough, nausea, vomiting, abdominal pain, diarrhea, and dehydration associated with a high fever, elevated liver enzymes, and lymphopenia. Subsequent investigation revealed acute infection with parvovirus B19. Following clinical improvement over 10-14 days solely with supportive care, her underlying disease remained in remission for about 7 months.
Bateman
H E
HE
Division of Rheumatology, Hospital for Special Surgery and Cornell University Weil Medical College, New York, New York 10021, USA. batermanh@hss.edu
Kirou
K A
KA
Paget
S A
SA
Crow
M K
MK
Yee
A M
AM
D000293:Adolescent; D001171:Arthritis, Juvenile / Q000150:complications / Q000503:physiopathology / Q000628:therapy* / Q000821:virology; D001691:Biological Therapy; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use; D010322:Parvoviridae Infections / Q000150:complications / Q000503:physiopathology*; D016732:Parvovirus B19, Human; D012074:Remission Induction
D008727:Methotrexate