title: Circadian clocks: A cry in the dark?
abstract: Cryptochrome proteins are key components of the circadian systems of both Drosophila and mammals. In Drosophila, they appear to be responsible for the entrainment of the circadian clock by the light-dark cycle, while in mammals they perform an important role in rhythm generation itself.
authors.affiliation: Department of Biology, Imperial College of Science, Technology and Medicine, Sir Alexander Fleming Building, South Kensington, London, SW7 2AZ, UK.
authors.forename: R J
authors.initials: RJ
authors.lastname: Lucas
authors.forename: R G
authors.initials: RG
authors.lastname: Foster
mesh_terms: D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology*; D056931:Cryptochromes; D003624:Darkness; D004330:Drosophila / Q000502:physiology; D029721:Drosophila Proteins; D005136:Eye Proteins; D005420:Flavoproteins / Q000502:physiology*; D008027:Light; D008322:Mammals / Q000502:physiology; D009687:Nuclear Proteins / Q000737:chemistry / Q000378:metabolism; D018462:Photobiology; D017956:Photoreceptor Cells, Invertebrate; D011487:Protein Conformation; D043562:Receptors, G-Protein-Coupled
chemical_list: D056931:Cryptochromes; D029721:Drosophila Proteins; D005136:Eye Proteins; D005420:Flavoproteins; D009687:Nuclear Proteins; D043562:Receptors, G-Protein-Coupled; C119828:cry protein, Drosophila