Cytotoxicity and microbicidal activity of electrolyzed strong acid water and acidic hypochlorite solution under isotonic conditions.
The cytotoxic effects of electrolyzed strong acid water and acidic hypochlorite solution, as well as these solutions after isotonization, against cultivated L cells were compared along with their microbicidal activities. Isotonization was accompanied by a reduction in the cytotoxic effects of these solutions against L cells. Microbicidal activity was also reduced somewhat but was still retained after isotonization. No difference was observed in these properties between these antiseptic solutions. The results obtained indicate that acidic hypochlorite solution may be useful as well as acidic electrolyzed water.
Okubo
K
K
Department of Pharmacy, Koseiren Murakami General Hospital, Murakami City, Japan.
Urakami
H
H
Tamura
A
A
D000818:Animals; D001419:Bacteria / Q000187:drug effects; D004202:Disinfectants / Q000494:pharmacology; D004572:Electrolysis; D006863:Hydrogen-Ion Concentration; D006997:Hypochlorous Acid / Q000494:pharmacology; D007552:Isotonic Solutions; D007739:L Cells; D051379:Mice; D014867:Water
D004202:Disinfectants; D007552:Isotonic Solutions; D014867:Water; D006997:Hypochlorous Acid