title: [The immunomodulating action of erythrocyte carrier-bound plant heteropolysaccharides in immersion cooling].
abstract: Heteropolysaccharides isolated from the racemes of families Polygonaceae, Tiliaceae, and Asteraceae intensify but do not normalize completely the development of the immune response in rats subjected to immersion (water) cooling. A similar effect is caused by erythrocytes of intact rats treated by heteropolysaccharides extracorporeally. On inclusion of heteropolysaccharides into the erythrocytic stroma of intact and cooled animals normalize the development of the immune response in rats subjected to immersion cooling.
authors.affiliation: Department of Pharmacology, Russian State Medical University, Moscow, Russia.
authors.forename: V A
authors.initials: VA
authors.lastname: Afanas'ev
authors.forename: I L
authors.initials: IL
authors.lastname: Laskova
authors.forename: B S
authors.initials: BS
authors.lastname: Uteshev
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D019659:Asteraceae; D003080:Cold Temperature / Q000009:adverse effects*; D004337:Drug Carriers; D004912:Erythrocytes; D007101:Immersion / Q000009:adverse effects*; D007111:Immunity, Cellular / Q000187:drug effects; D007114:Immunization / Q000379:methods / Q000706:statistics & numerical data; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology; D019664:Polygonaceae; D011134:Polysaccharides / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D018709:Statistics, Nonparametric; D014197:Trees
chemical_list: D000276:Adjuvants, Immunologic; D004337:Drug Carriers; D010936:Plant Extracts; D011134:Polysaccharides