[A case of metastatic nephroblastoma in an adult with favorable outcome under cisplatyl, etoposide].
Wilm's tumor is exceptional in adulthood. Its treatment is based on radical nephrectomy, adjuvant chemotherapy and radiotherapy. The prognosis is poorer compared with children because adults present more frequently with advanced stages and chemotherapy has a moderate efficacy. The various protocols of chemotherapy and the indications of radiotherapy are not defined with precision, mainly due to the rarity of the disease. The authors report a case of adult Wilm's tumor with a favorable evolution followed 4 years in spite of an unfavorable histology, lung metastases and a relapse after a first chemotherapy.
Blois
N
N
Service d'Urologie, Hôpital Huriez, Lille, France.
Colomb
J B
JB
Goullet
E
E
Biserte
J
J
Mazeman
E
E
D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D005047:Etoposide / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000188:drug therapy*; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary; D008297:Male; D009392:Nephrectomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D009396:Wilms Tumor / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary
D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D005047:Etoposide; D002945:Cisplatin