title: In-vitro activity of antibiotics against Legionella pneumophila isolates from water systems.
abstract: The activity of five antibiotics was tested against 82 isolates of Legionella pneumophila obtained from water systems in nine European countries. All isolates were susceptible to clarithromycin (MICs 0. 03-0.5 mg/L), erythromycin (MICs 0.125-2.0 mg/L), ciprofloxacin (MICs 0.06-0.25 mg/L), pefloxacin (MICs 0.06-0.5 mg/L) and rifampicin (MICs < or = 0.007-0.015 mg/L). It seems that antibiotics used for legionellosis continue to exhibit good activity against L. pneumophila isolates from environmental sources in European countries.
authors.affiliation: Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54 006 Thessaloniki, Greece. atsakris@med.auth.gr
authors.forename: A
authors.initials: A
authors.lastname: Tsakris
authors.forename: S
authors.initials: S
authors.lastname: Alexiou-Daniel
authors.forename: E
authors.initials: E
authors.lastname: Souliou
authors.forename: A
authors.initials: A
authors.lastname: Antoniadis
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D005060:Europe; D016952:Legionella pneumophila / Q000187:drug effects* / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D014871:Water Microbiology; D014881:Water Supply
chemical_list: D000900:Anti-Bacterial Agents