1H MRS detects polyunsaturated fatty acid accumulation during gene therapy of glioma: implications for the in vivo detection of apoptosis.
Hakumäki
J M
JM
NMR Research Group, A.I.Virtanen Institute for Molecular Sciences, University of Kuopio, FIN-70211 Kuopio, Finland.
Poptani
H
H
Sandmair
A M
AM
Ylä-Herttuala
S
S
Kauppinen
R A
RA
D017209:Apoptosis / Q000187:drug effects; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology / Q000628:therapy* / Q000648:ultrastructure; D005231:Fatty Acids, Unsaturated / Q000378:metabolism*; D015774:Ganciclovir / Q000494:pharmacology / Q000627:therapeutic use; D015316:Genetic Therapy; D005910:Glioma / Q000378:metabolism / Q000473:pathology / Q000628:therapy* / Q000648:ultrastructure; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008854:Microscopy, Electron; D011522:Protons
D005231:Fatty Acids, Unsaturated; D011522:Protons; D015774:Ganciclovir