title: [Eikenella corrodens: five year experience in a general hospital].
abstract: BACKGROUND
  Eikenella corrodens is a Gram negative bacillus that colonizes oropharyngeal and digestive mucous membranes. It is difficult to isolate in the laboratory. This might be the reason why its implication in different types of infection is not well known. We report a five year experience in a general hospital.
  
  
  METHODS
  Charts of 125 infections have been retrospectively reviewed. No selective medium was employed for the isolation.
  
  
  RESULTS
  Infections were related to oral cavity in 68 patients (54%) and to gastrointestinal tract in 45 (36%); in 12 no clear source could be found. The prevailing infections were: postsurgical 32, apendiceal 22, abscesses 22, and traumatic wounds 12. Seventy two percent of the patients were adults and 93% were hospitalized. Eighteen patients had a neoplasia, 6 were diabetic, and 3 had some kind of immunodeficiency. Etiology was polymicrobial in 91% of the cases, the prevailing association being with Streptococcus spp. (74%). Only 15 patients had a pure culture, 11 of which had received previous antibiotic treatment. The most serious infections were a subdural empyema secondary to sinusitis, a mediastinitis following a mouth floor abscess, and a peritonitis with pleural empyema preceded by an hepatic abscess. The three were polymicrobial. Outcome was always satisfactory with no associated death.
  
  
  CONCLUSIONS
  The origin of these infections is almost always clearly related with its habitat, but their spectrum is wide. Polymicrobial condition of most of them makes diagnosis as well as interpretation of its clinical meaning difficult. Nevertheless, association of E. corrodens with serious or slow healing infections fully justifies the efforts towards its isolation and the choice of antibiotics to which it is susceptible.
authors.affiliation: Servicio de Microbiología, Hospital Vall d'Hebron, Barcelona.
authors.forename: I
authors.initials: I
authors.lastname: Gasser
authors.forename: G
authors.initials: G
authors.lastname: Moreno
authors.forename: A
authors.initials: A
authors.lastname: Ferrer
authors.forename: J A
authors.initials: JA
authors.lastname: Capdevila
authors.forename: I
authors.initials: I
authors.lastname: Valle
mesh_terms: D000328:Adult; D016124:Eikenella corrodens; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology*; D006769:Hospitals, General; D006801:Humans; D010538:Peritonitis / Q000453:epidemiology; D010612:Pharyngitis / Q000453:epidemiology; D012189:Retrospective Studies