title: The "Brisighella Terme" Project: effectiveness of preventive medicine in thermal ambient. Hematochemical parameters.
abstract: BACKGROUND
  The main aims of the Brisighella Terme Project are: 1. evaluation of feasibility and effectiveness of preventive medicine intervention in thermal ambient; 2. identification of subjects with cardiovascular risk factors; 3. to give patients informations on risk factor correction. The data of this work concern the hematochemical parameters: CT, HDL-CT, LDL-CT, TG, ApoA1, ApoB, fibrinogen, GOT, GPT, CPK, glucose, uric acid.
  
  
  METHODS
  CT, HDL-CT (after precipitation of the non-HDL fractions), TG, glucose, uric acid are evaluated by enzymatic-colorimetric reactions; GOT, GPT, CK by enzymatic method. ApoA1, ApoB, fibrinogen by immunoturbidimetric methods. LDL-CT is calculated by the Friedewald formula.
  
  
  RESULTS
  390 subjects spontaneously adhered to the Brisighella Terme Project. Of these subjects 38% requested laboratory service and we observed a 47% increment, from 1995 to 1996, with regard to this request. Females showed higher mean values than males of these parameters: CT, LDL-CT, HDL-CT, ApoA1, ApoB, fibrinogen, CPK. 55% of females had LDL-CT > 159 mg/dl, values considered high risk for cardiovascular diseases. 36% of males presented HDL-CT < 40 mg/dl, with 2 cases < 25 mg/dl. TG values > 399 mg/dl were found only in males (2%). We identified new cases of hypertriglyceridaemia, hypercholesterolaemia and hypoHD Laemia; these metabolic pathologies had not yet been diagnosed, whereas the patients already knew they were affected by hyperglicaemia or hyperuricaemia.
  
  
  CONCLUSIONS
  People's interest in the Brisighella Terme Project, new case identification, the possibility of providing correct information about risk factors and healthy life style confirm the feasibility and effectiveness of preventive medicine in a thermal ambient.
authors.affiliation: Dpt. Clinical Medicine and Applied Biotechnology, Center of Atherosclerosis G.C. Descovich Cervia, Italy.
authors.forename: Z
authors.initials: Z
authors.lastname: Sangiorgi
authors.forename: S
authors.initials: S
authors.lastname: Pignatelli
authors.forename: N
authors.initials: N
authors.lastname: Pascarelli
authors.forename: L
authors.initials: L
authors.lastname: Gentilini
authors.forename: M R
authors.initials: MR
authors.lastname: Facchino
authors.forename: A
authors.initials: A
authors.lastname: Dormi
authors.forename: R
authors.initials: R
authors.lastname: Mambelli
authors.forename: M L
authors.initials: ML
authors.lastname: Malkowski
authors.forename: A
authors.initials: A
authors.lastname: Gaddi
mesh_terms: D000368:Aged; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000517:prevention & control*; D004032:Diet; D005260:Female; D006266:Health Education / Q000379:methods*; D006801:Humans; D008019:Life Style; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011322:Primary Prevention; D012307:Risk Factors
chemical_list: D008055:Lipids