title: Late acquired words in childhood are lost earlier in primary progressive aphasia.
abstract: The psycholinguistic nature of the dissolution of the mental lexicon in a primary progressive aphasic patient was investigated in light of the general regression hypothesis that language dissolution is the inverse of language acquisition. Four years after onset of the symptoms, the patient scored 60% correct on a picture naming test, exhibiting some effects of lexical and sublexical age-of-acquisition, but 7 years after onset, he scored only 15% correct. While even a weak form of the regression hypothesis is not fully supported, age-of-acquisition effects seem to be preserved throughout the course of the lexical dissolution. Some implications are briefly discussed for future research.
authors.affiliation: Rehabilitation Unit, Osaka University Hospital, Osaka, Japan. junyamd@ipc.hiroshima-u.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Ukita
authors.forename: K
authors.initials: K
authors.lastname: Abe
authors.forename: J
authors.initials: J
authors.lastname: Yamada
mesh_terms: D000367:Age Factors; D001037:Aphasia / Q000175:diagnosis* / Q000209:etiology*; D001284:Atrophy / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology; D003071:Cognition / Q000502:physiology; D018450:Disease Progression; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D015899:Tomography, Emission-Computed, Single-Photon; D014825:Vocabulary