Dosage compensation: roX marks the spot.
The roX genes of Drosophila produce a transcript that is spliced and polyadenylated but not translated. Recent work has shown that these genes provide an element that the dosage compensation complex of Drosophila uses to initiate its association with the X chromosome.
Lucchesi
J C
JC
Department of Biology, 1510 Clifton Road, Emory University, Atlanta, Georgia 30322, USA. lucchesi@biology.emery.edu
D000818:Animals; D004303:Dosage Compensation, Genetic; D004330:Drosophila / Q000235:genetics*; D017344:Genes, Insect / Q000502:physiology; D014176:Protein Biosynthesis; D014960:X Chromosome