Is neuroprotection a viable therapy for glaucoma?
Treatment of glaucoma continues to be directed at lowering intraocular pressure to decrease the likelihood of disease progression. In the future intraocular pressure reduction might be augmented by other therapeutic approaches. Interest has been increasing in preventing progression of glaucomatous optic neuropathy using approaches based on the premise that glaucoma is a neurodegenerative disease. Neuroprotection of the glaucomatous optic nerve therefore would be an adjuctive therapeutic paradigm for use with conventional intraocular pressure-lowering treatments or by itself.
Weinreb
R N
RN
Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla 92093-0946, USA.
Levin
L A
LA
D000818:Animals; D002986:Clinical Trials as Topic; D018450:Disease Progression; D005901:Glaucoma / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D009901:Optic Nerve Diseases / Q000188:drug therapy* / Q000503:physiopathology; D012165:Retinal Ganglion Cells / Q000187:drug effects
D018696:Neuroprotective Agents