title: Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin.
abstract: The structure of a homonojirimycin isomer isolated from Aglaonema treublii and originally proposed as alpha-3,4-di-epi-homonojirimycin was revised to alpha-4-epi-homonojirimycin 3 ("alpha-homoallonojirimycin") on the basis of NMR analysis and synthetic studies. Its activity as a glycosidase inhibitor is compared to that of other homonojirimycin isomers.
authors.affiliation: Institut de Chimie Organique et Analytique (I.C.O.A.), Faculté des Sciences, Orléans, France. Olivier.Martin@univ-orleans.fr
authors.forename: O R
authors.initials: OR
authors.lastname: Martin
authors.forename: P
authors.initials: P
authors.lastname: Compain
authors.forename: H
authors.initials: H
authors.lastname: Kizu
authors.forename: N
authors.initials: N
authors.lastname: Asano
mesh_terms: D017485:1-Deoxynojirimycin / Q000031:analogs & derivatives; D001372:Aza Compounds / Q000138:chemical synthesis*; D002236:Carbohydrate Conformation; D002241:Carbohydrates / Q000737:chemistry; D004791:Enzyme Inhibitors / Q000138:chemical synthesis*; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors; D050112:Imino Pyranoses; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010880:Piperidines / Q000138:chemical synthesis* / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry; D013329:Structure-Activity Relationship
chemical_list: D001372:Aza Compounds; D002241:Carbohydrates; D004791:Enzyme Inhibitors; D050112:Imino Pyranoses; D010880:Piperidines; D010936:Plant Extracts; C106502:homonojirimycin; D017485:1-Deoxynojirimycin; D006026:Glycoside Hydrolases