Choroidal neovascularization following macular hole surgery.
BACKGROUND
Retinal pigment epitheliopathy, a recognized finding in eyes that have undergone macular hole surgery, may limit visual outcome and predispose to the development of choroidal neovascularization (CNV). This study reports on the features and outcomes of CNV following otherwise successful surgery for idiopathic macular holes.


METHODS
Case series including three eyes of two patients who developed CNV following macular hole surgery.


RESULTS
Choroidal neovascularization developed 3 to 30 months after macular hole surgery. The CNV was crescent-shaped, surrounding a central area of retinal pigment epithelial mottling that corresponded to the site of the macular hole in all three cases. All neovascular membranes were adjacent to the fovea and were associated with substantial leakage of fluorescein. The macular hole remained closed in all cases.


CONCLUSIONS
Choroidal neovascularization is a rare complication following macular hole surgery. Retinal pigment epitheliopathy and defects in the Bruch's membrane, pre-existing or secondary to surgery, may be predisposing factors.
Tabandeh
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Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, Florida 33101, USA.
Smiddy
W E
WE
D000368:Aged; D002829:Choroid / Q000473:pathology*; D020256:Choroidal Neovascularization / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D005451:Fluorescein Angiography; D005466:Fluorocarbons / Q000008:administration & dosage; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D012086:Reoperation; D012167:Retinal Perforations / Q000175:diagnosis / Q000601:surgery*; D014792:Visual Acuity; D014821:Vitrectomy / Q000009:adverse effects*
D005466:Fluorocarbons; C042852:perflutren