Studies on the constituents of Cyclanthera pedata fruits: isolation and structure elucidation of new triterpenoid saponins.
The isolation of nine triterpenoid saponins (1-9), among them six new natural compounds (1-6), from the MeOH extract of the fruits of Cyclanthera pedata is reported. All of the structures were elucidated by spectroscopic methods, including the concerted application of one-dimensional (1)H-(1)H total correlation spectroscopy, (1)H-(1)H nuclear Overhauser effect spectroscopy), and (13)C-(13)C DEPT-NMR and two-dimensional NMR techniques (double-quantum filtered correlated spectroscopy, rotating-frame Overhauser enhancement spectroscopy, heteronuclear single quantum coherence, and heteronuclear multiple bond correlation). A comparative study of seeds and fruits has been also carried out.
De Tommasi
N
N
Dipartimento di Scienze Farmaceutiche, Facoltà di Farmacia, Università di Salerno, Ponte Don Melillo Invariante 11C, 84084 Fisciano (SA), Italy.
De Simone
F
F
Speranza
G
G
Pizza
C
C
D005638:Fruit / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D008956:Models, Chemical; D010568:Peru; D012503:Saponins / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*
D012503:Saponins; D014315:Triterpenes