title: Wasalexins A and B, new phytoalexins from wasabi: isolation, synthesis, and antifungal activity.
abstract: The chemical structure determination of two phytoalexins from wasabi (Wasabia japonica, syn. Eutrema wasabi), a plant resistant to virulent isolates of the blackleg fungus [Leptosphaeria maculans (Desm.) Ces. et de Not., asexual stage Phoma lingam (Tode ex Fr.) Desm.], as well as their synthesis and antifungal activity towards isolates of P. lingam and P. wasabiae is reported.
authors.affiliation: Department of Chemistry, University of Saskatchewan, Saskatoon, SK, Canada.
authors.forename: M S
authors.initials: MS
authors.lastname: Pedras
authors.forename: J L
authors.initials: JL
authors.lastname: Sorensen
authors.forename: F I
authors.initials: FI
authors.lastname: Okanga
authors.forename: I L
authors.initials: IL
authors.lastname: Zaharia
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis / Q000302:isolation & purification* / Q000494:pharmacology; D019607:Brassicaceae / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D013440:Sulfides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D007211:Indoles; D013440:Sulfides; C401941:wasalexin A