title: Characterization of blood culture isolates of Streptococcus dysgalactiae subsp. equisimilis possessing Lancefield's group A antigen.
abstract: For three human blood culture isolates of beta-hemolytic streptococci with Lancefield's serogroup A antigen, phylogenetic analysis of the 16S rRNA genes confirmed biochemical identification as Streptococcus dysgalactiae subsp. equisimilis. Genes encoding M or M-like proteins, which are considered to be major virulence determinants in streptococci, were detected in all of these strains. Our data clearly demonstrate that for beta-hemolytic streptococci, the species assignment should not be based on the results of serogrouping alone.
authors.affiliation: Institute of Medical Microbiology and National Reference Center for Streptococci, University Hospital RWTH Aachen, Aachen, Germany.
authors.forename: C M
authors.initials: CM
authors.lastname: Brandt
authors.forename: G
authors.initials: G
authors.lastname: Haase
authors.forename: N
authors.initials: N
authors.lastname: Schnitzler
authors.forename: R
authors.initials: R
authors.lastname: Zbinden
authors.forename: R
authors.initials: R
authors.lastname: Lütticken
mesh_terms: D000368:Aged; D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins / Q000235:genetics; D001769:Blood / Q000382:microbiology*; D002352:Carrier Proteins / Q000235:genetics; D003470:Culture Media; D005260:Female; D020459:Genes, rRNA; D006801:Humans; D005779:Immunodiffusion; D008297:Male; D016133:Polymerase Chain Reaction; D011135:Polysaccharides, Bacterial / Q000032:analysis*; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012703:Serotyping; D013290:Streptococcal Infections / Q000382:microbiology*; D013291:Streptococcus / Q000145:classification* / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D014774:Virulence / Q000235:genetics
chemical_list: D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D002352:Carrier Proteins; D003470:Culture Media; D011135:Polysaccharides, Bacterial; D012336:RNA, Ribosomal, 16S; C014689:streptococcal M protein; C036112:streptococcal polysaccharide group A