Prolactinoma causing secondary amenorrhea in a woman with Ullrich-Turner syndrome.
This is the case report of a girl who was diagnosed as having Ullrich-Turner mosaic at the age of 12 years. She had normal pubertal development and menarche at the age of 15 years. The patient had regular menstrual cycles for 12 months before developing secondary amenorrhea. She was started on estrogen/gestagen replacement therapy by her gynecologist. Several months later a prolactinoma was diagnosed by laboratory and imaging techiques. A second-generation dopamine agonist led to almost regular cycles. Therefore, even in patients with susceptibility to ovarian failure secondary amenorrhea necessitates thorough diagnostic investigation. Copyrightz1999S.KargerAG,Basel
Dötsch
J
J
Klinik für Kinder und Jugendliche, Friedrich Alexander University Erlangen, Hannover, Germany.
Schoof
E
E
Hensen
J
J
Dörr
H G
HG
D000568:Amenorrhea / Q000209:etiology*; D000634:Aminoquinolines / Q000627:therapeutic use; D002648:Child; D018491:Dopamine Agonists / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009030:Mosaicism; D010911:Pituitary Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D015175:Prolactinoma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D012729:Sex Chromosome Aberrations; D014424:Turner Syndrome / Q000150:complications*
D000634:Aminoquinolines; D018491:Dopamine Agonists; C046650:quinagolide