title: Dural sinus thrombosis endovascular therapy.
abstract: Dural sinus thrombosis is a relatively rare, but potentially devastating disease. The problem occurs when there is extensive thrombosis of the intracranial dural sinuses, the outflow channels of venous blood from the brain. If recanalization does not occur, venous hypertension can lead to cerebral edema, infarction, and hemorrhage. Treatment of this disease usually involves anticoagulants, but with mixed results. Endovascular approaches using direct infusion of thrombolytic drugs into the occluded sinuses may result in excellent recanalization and improved patient outcomes.
authors.affiliation: Department of Neurological Surgery, Dotter Interventional Institute, Oregon Health Sciences University, Portland, USA.
authors.forename: F P
authors.initials: FP
authors.lastname: Hsu
authors.forename: T
authors.initials: T
authors.lastname: Kuether
authors.forename: G
authors.initials: G
authors.lastname: Nesbit
authors.forename: S L
authors.initials: SL
authors.lastname: Barnwell
mesh_terms: D003392:Cranial Sinuses; D004388:Dura Mater / Q000098:blood supply; D006801:Humans; D012851:Sinus Thrombosis, Intracranial / Q000175:diagnosis / Q000188:drug therapy*; D015912:Thrombolytic Therapy / Q000379:methods*