Giant hydronephrosis due to a ureteral stone, and elevated serum levels of CA 19-9.
CA 19-9 is a widely used tumor marker. However, an elevation in serum CA 19-9 can occur in some patients with benign disorders such as cholecystolithiasis in the absence of tumor. We treated a case of acquired ureteral stone-induced giant hydronephrosis with markedly elevated serum CA 19-9 values. After nephrectomy, the serum CA 19-9 level returned to normal. No malignant cells were found in the tissues of the resected kidney. Localization of CA 19-9 was confirmed by immunohistochemical staining of the renal pelvic mucosa. A detailed case report is presented with a review of the literature.
Shudo
R
R
Department of Internal Medicine, Shizunai Municipal Hospital.
Saito
T
T
Takahashi
K
K
Horita
K
K
Waku
K
K
Honma
I
I
Sato
T
T
D000328:Adult; D018395:CA-19-9 Antigen / Q000032:analysis / Q000097:blood*; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000097:blood / Q000209:etiology* / Q000601:surgery; D007668:Kidney / Q000473:pathology; D009392:Nephrectomy; D012307:Risk Factors; D014514:Ureteral Calculi / Q000097:blood / Q000150:complications*
D018395:CA-19-9 Antigen