Ecthyma gangrenosum as a very early herald of acute lymphoblastic leukaemia.
Ecthyma gangrenosum is a manifestation of cutaneous infection by Pseudomonas aeruginosa. The lesion may be associated with immunocompromise, in particular neutropenia. We present a case of ecthyma gangrenosum in a previously healthy child who 3 months later developed acute lymphoblastic leukaemia; we use this to illustrate the lack of information on the growth rate of malignant and premalignant leukaemic cells in children.
Pouryousefi
A
A
Department of Paediatrics, Ealing Hospital NHS Trust, Middlesex, UK.
Foland
J
J
Michie
C
C
Cummins
M
M
D000912:Antibodies, Neoplasm; D015703:Antigens, CD / Q000276:immunology; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D002675:Child, Preschool; D004473:Ecthyma / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D011552:Pseudomonas Infections / Q000150:complications; D017192:Skin Diseases, Bacterial / Q000382:microbiology; D013997:Time Factors
D000912:Antibodies, Neoplasm; D015703:Antigens, CD