title: Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1.
abstract: The complete genome sequence of the radiation-resistant bacterium Deinococcus radiodurans R1 is composed of two chromosomes (2,648,638 and 412,348 base pairs), a megaplasmid (177,466 base pairs), and a small plasmid (45,704 base pairs), yielding a total genome of 3,284, 156 base pairs. Multiple components distributed on the chromosomes and megaplasmid that contribute to the ability of D. radiodurans to survive under conditions of starvation, oxidative stress, and high amounts of DNA damage were identified. Deinococcus radiodurans represents an organism in which all systems for DNA repair, DNA damage export, desiccation and starvation recovery, and genetic redundancy are present in one cell.
authors.affiliation: Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
authors.forename: O
authors.initials: O
authors.lastname: White
authors.forename: J A
authors.initials: JA
authors.lastname: Eisen
authors.forename: J F
authors.initials: JF
authors.lastname: Heidelberg
authors.forename: E K
authors.initials: EK
authors.lastname: Hickey
authors.forename: J D
authors.initials: JD
authors.lastname: Peterson
authors.forename: R J
authors.initials: RJ
authors.lastname: Dodson
authors.forename: D H
authors.initials: DH
authors.lastname: Haft
authors.forename: M L
authors.initials: ML
authors.lastname: Gwinn
authors.forename: W C
authors.initials: WC
authors.lastname: Nelson
authors.forename: D L
authors.initials: DL
authors.lastname: Richardson
authors.forename: K S
authors.initials: KS
authors.lastname: Moffat
authors.forename: H
authors.initials: H
authors.lastname: Qin
authors.forename: L
authors.initials: L
authors.lastname: Jiang
authors.forename: W
authors.initials: W
authors.lastname: Pamphile
authors.forename: M
authors.initials: M
authors.lastname: Crosby
authors.forename: M
authors.initials: M
authors.lastname: Shen
authors.forename: J J
authors.initials: JJ
authors.lastname: Vamathevan
authors.forename: P
authors.initials: P
authors.lastname: Lam
authors.forename: L
authors.initials: L
authors.lastname: McDonald
authors.forename: T
authors.initials: T
authors.lastname: Utterback
authors.forename: C
authors.initials: C
authors.lastname: Zalewski
authors.forename: K S
authors.initials: KS
authors.lastname: Makarova
authors.forename: L
authors.initials: L
authors.lastname: Aravind
authors.forename: M J
authors.initials: MJ
authors.lastname: Daly
authors.forename: K W
authors.initials: KW
authors.lastname: Minton
authors.forename: R D
authors.initials: RD
authors.lastname: Fleischmann
authors.forename: K A
authors.initials: KA
authors.lastname: Ketchum
authors.forename: K E
authors.initials: KE
authors.lastname: Nelson
authors.forename: S
authors.initials: S
authors.lastname: Salzberg
authors.forename: H O
authors.initials: HO
authors.lastname: Smith
authors.forename: J C
authors.initials: JC
authors.lastname: Venter
authors.forename: C M
authors.initials: CM
authors.lastname: Fraser
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics; D002374:Catalase / Q000235:genetics; D002876:Chromosomes, Bacterial / Q000235:genetics; D004249:DNA Damage; D004260:DNA Repair / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics; D004734:Energy Metabolism; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D006095:Gram-Positive Cocci / Q000737:chemistry / Q000145:classification / Q000235:genetics* / Q000528:radiation effects; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D018384:Oxidative Stress; D020161:Physical Chromosome Mapping; D010957:Plasmids; D011836:Radiation Tolerance; D012091:Repetitive Sequences, Nucleic Acid; D017422:Sequence Analysis, DNA; D013482:Superoxide Dismutase / Q000235:genetics; D013824:Thermus / Q000737:chemistry / Q000235:genetics; D014466:Ultraviolet Rays
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D002374:Catalase; D013482:Superoxide Dismutase