title: Effect of cholecystectomy on bowel function: a prospective, controlled study.
abstract: BACKGROUND
  Published estimates of the prevalence of postcholecystectomy diarrhoea derive from retrospective or uncontrolled data. They ignore functional bowel syndromes and possible changes in diet and drug use.
  
  
  OBJECTIVE
  To determine prospectively whether and how often cholecystectomy leads to changes in bowel function and bowel symptoms, especially to liquid stools, over and above any non-specific effect of laparoscopic surgery.
  
  
  METHODS
  
  
  
  METHODS
  106 adults undergoing laparoscopic cholecystectomy (85 women, 21 men).
  
  
  METHODS
  37 women undergoing laparoscopic sterilisation.
  
  
  METHODS
  Before and 2-6 months after surgery patients were administered questionnaires about bowel frequency, bowel symptoms, diet, and drugs, and kept records of five consecutive defecations with assessment of stool form or appearance on a seven point scale.
  
  
  RESULTS
  In cholecystectomised women, stated bowel frequency increased, on average by one movement a week, and fewer subjects felt that they became constipated. However, records showed no consistent change in bowel frequency, stool form, or defecatory symptoms. Six women reported diarrhoea after the operation but in only one was it clearly new and in her it was mild. Change in dietary fibre intake did not associate with change in bowel function but stopping constipating drugs did in a minority. In women being sterilised there was no consistent change in bowel function. In men having cholecystectomy no consistent changes were observed.
  
  
  CONCLUSIONS
  In women, cholecystectomy leads to the perception of less constipation and slightly more frequent defecations but short term recordings show no consistent change in bowel function. Clinical diarrhoea develops rarely and is not severe.
authors.affiliation: University Department of Medicine, Bristol Royal Infirmary, Bristol, UK.
authors.forename: S D
authors.initials: SD
authors.lastname: Hearing
authors.forename: L A
authors.initials: LA
authors.lastname: Thomas
authors.forename: K W
authors.initials: KW
authors.lastname: Heaton
authors.forename: L
authors.initials: L
authors.lastname: Hunt
mesh_terms: D000328:Adult; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects; D003248:Constipation / Q000209:etiology; D003672:Defecation; D003967:Diarrhea / Q000209:etiology*; D004043:Dietary Fiber / Q000008:administration & dosage; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D011184:Postoperative Period; D011446:Prospective Studies; D013246:Sterilization, Tubal; D011795:Surveys and Questionnaires