Fruit and vegetables and ischaemic heart disease: systematic review or misleading meta-analysis?
In a recent meta-analysis published in this journal Law and Morris (1998) sought to quantify the association between fruit and vegetable intake and ischaemic heart disease. They estimated that for six dietary markers of fruit and vegetables the risk of ischaemic heart disease was on average reduced by 15% at the 90th centile of consumption when compared to the 10th centile. In this commentary we will argue that this figure is misleading; and that a more cautious and considered approach should be adopted when reviewing the body of evidence that is available on this issue.
Ness
A
A
Egger
M
M
Powles
J
J
D006801:Humans; D004032:Diet; D005638:Fruit; D015201:Meta-Analysis as Topic; D017202:Myocardial Ischemia / Q000517:prevention & control; D012307:Risk Factors; D014675:Vegetables; D000078202:Systematic Reviews as Topic