Algorithm for the treatment of rapid cycling.
Rapid cycling is a clinical subtype of bipolar mood disorder that has four or more episodes during the previous 12 months and has poor response to lithium (Li) prophylaxis treatment. Therefore it is said the refractory mood disorder and algorithm for treatment of rapid cycling is to be expected. The first choice of drug for rapid cycling is Li, the second choice is carbamazepine (CBZ) or valproic acid (VPA), in addition to Li, the third choice is clonazepam (CNZP) in addition to Li, and CBZ or VPA, the fourth choice is levothyroxine or bromocriptine in addition to them, and the fifth choice is electroconvulsive therapy.
Yamada
K
K
Department of Psychiatry, Urafune Hospital of Yokohama City University School of Medicine, Yokohama, Japan.
D000465:Algorithms; D018692:Antimanic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D001714:Bipolar Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D002220:Carbamazepine / Q000008:administration & dosage / Q000009:adverse effects; D002998:Clonazepam / Q000008:administration & dosage / Q000009:adverse effects; D003527:Cyclothymic Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D004359:Drug Therapy, Combination; D006801:Humans; D016651:Lithium Carbonate / Q000008:administration & dosage / Q000009:adverse effects; D016896:Treatment Outcome; D014635:Valproic Acid / Q000008:administration & dosage / Q000009:adverse effects
D018692:Antimanic Agents; D016651:Lithium Carbonate; D002220:Carbamazepine; D002998:Clonazepam; D014635:Valproic Acid