title: Concept, design, and preclinical evaluation of quinolonyl lactam antibacterials.
authors.affiliation: Procter & Gamble Pharmaceuticals, Health Care Research Center Mason, Ohio 45040, USA.
authors.forename: P M
authors.initials: PM
authors.lastname: Hershberger
authors.forename: T P
authors.initials: TP
authors.lastname: Demuth
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects; D015195:Drug Design; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D007769:Lactams; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D015363:Quinolones / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D018440:beta-Lactam Resistance
chemical_list: D000900:Anti-Bacterial Agents; D007769:Lactams; D015363:Quinolones