title: Acceptability of two spermicides in five countries.
abstract: Data from a large, international, multicenter, randomized trial were analyzed to compare the acceptability of two nonoxynol-9 spermicide preparations. Women who wished to use a spermicide for contraception were randomly assigned to use either a foaming tablet (n = 383) or a nonoxynol-9 film (n = 382) for 28 weeks as their only method of contraception. Participants completed questionnaires about acceptability of the assigned product 4 weeks after admission and at discontinuation. Women in both groups had very favorable opinions of the spermicide. The proportion of women who said that they liked their assigned product very much was 50% in the tablet group and 55% in the film group. Significantly more women in the film group rated the spermicide difficult to insert and stated that the product stuck to the finger during insertion. More women in the tablet group said that the product was messy and that, at least once, it did not dissolve. In both groups, liking the product was significantly associated with consistency of use, but not with subsequent pregnancy. Participants' male partners had little influence on participants' opinions about, or use of, the spermicides. Although previous analyses showed that both spermicides are associated with high pregnancy rates, they are both highly acceptable to most women.
authors.affiliation: Biomedical Affairs Division, Family Health International, Research Triangle Park, NC 27709, USA. eraymond@fhi.org
authors.forename: E
authors.initials: E
authors.lastname: Raymond
authors.forename: G
authors.initials: G
authors.lastname: Alvarado
authors.forename: L
authors.initials: L
authors.lastname: Ledesma
authors.forename: S
authors.initials: S
authors.lastname: Diaz
authors.forename: S
authors.initials: S
authors.lastname: Bassol
authors.forename: E
authors.initials: E
authors.lastname: Morales
authors.forename: V
authors.initials: V
authors.lastname: Fernandez
authors.forename: G
authors.initials: G
authors.lastname: Carlos
mesh_terms: D000293:Adolescent; D000328:Adult; D004484:Ecuador; D004522:Educational Status; D005260:Female; D005869:Ghana; D006166:Guatemala; D006801:Humans; D008297:Male; D017533:Marital Status; D008800:Mexico; D017137:Nonoxynol / Q000008:administration & dosage*; D017060:Patient Satisfaction; D013089:Spermatocidal Agents / Q000008:administration & dosage*; D011795:Surveys and Questionnaires; D013607:Tablets; D014481:United States
chemical_list: D013089:Spermatocidal Agents; D013607:Tablets; D017137:Nonoxynol