Cerebral vasoreactivity to arterial carbon dioxide tension in preterm infants: the effect of ibuprofen.
Cerebral vasoreactivity to CO(2), calculated by linear regression of total cerebral hemoglobin, measured by near infrared spectroscopy, and corresponding PaCO(2), in infants <32 weeks' gestation, was found to be unaffected by the administration of ibuprofen, which was given on the first postnatal day as prophylaxis against patent ductus arteriosus.
Mosca
F
F
Patologia Neonatale, Clinica "Mangiagalli," Milan, Italy.
Bray
M
M
Colnaghi
M R
MR
Fumagalli
M
M
Compagnoni
G
G
D001921:Brain / Q000098:blood supply; D002245:Carbon Dioxide / Q000097:blood*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D004374:Ductus Arteriosus, Patent / Q000517:prevention & control*; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use*; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000517:prevention & control*; D019265:Spectroscopy, Near-Infrared
D006454:Hemoglobins; D002245:Carbon Dioxide; D007052:Ibuprofen