The relationship between the BOLD-induced T(2) and T(2)(*): a theoretical approach for the vasculature of myocardium.
Recently the blood oxygenation level-dependent (BOLD)-related T(2)* of myocardium was derived as an analytical function of intracapillary blood volume, blood oxygenation, and nuclear spin diffusion. The basis of this approach was to approximate the diffusion-induced field fluctuations a nuclear spin is subjected to by strong collision dynamics, i.e., the field fluctuations are uncorrelated. The same analysis is now performed for spin echo experiments that gives myocardial T(2) as a function of the parameters above and the echotime. An analytical relationship between T(2) and T(2)* relaxation is derived. The dependence of T(2) on diffusion, echo time, and blood oxygenation is congruent with simulation and experimental data. Magn Reson Med 42:1004-1010, 1999.
Bauer
W R
WR
II. Medizinische Universitätsklinik Mannheim/Heidelberg, Mannheim, Germany.
Nadler
W
W
Bock
M
M
Schad
L R
LR
Wacker
C
C
Hartlep
A
A
Ertl
G
G
D000818:Animals; D003331:Coronary Vessels / Q000033:anatomy & histology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008962:Models, Theoretical; D009206:Myocardium / Q000378:metabolism; D010100:Oxygen / Q000097:blood*
D010100:Oxygen