title: A case of anaplastic large cell (Ki-1) lymphoma of B-cell phenotype, occurring in Waldenström's macroglobulinemia.
abstract: A case of anaplastic large cell (Ki-1) lymphoma of B-cell lineage occurred in a 59-year-old male with Waldenström's macroglobulinemia. Immunostaining of the lymphoma cells showed sporadic positivity for IgM and occasional positivity for kappa chain. This immunoglobulin specificity is the same as that of plasmacytoid lymphocytes in the bone marrow; therefore anaplastic transformation of Waldenström's macroglobulinemia was strongly suggested. This seems to be the first reported case of anaplastic large cell lymphoma, confirmed by CD30 expression, arising in Waldenström's macroglobulinemia.
authors.affiliation: Department of Pathology, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hamada
authors.forename: H
authors.initials: H
authors.lastname: Ishizuka
authors.forename: Y
authors.initials: Y
authors.lastname: Asai
authors.forename: T
authors.initials: T
authors.lastname: Yamazaki
authors.forename: U
authors.initials: U
authors.lastname: Sawada
authors.forename: H
authors.initials: H
authors.lastname: Hasegawa
authors.forename: T
authors.initials: T
authors.lastname: Uchida
mesh_terms: D018951:Antigens, CD20 / Q000378:metabolism; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D007124:Immunoenzyme Techniques; D007075:Immunoglobulin M / Q000378:metabolism; D017730:Ki-1 Antigen / Q000378:metabolism; D008198:Lymph Nodes / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000378:metabolism / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000473:pathology
chemical_list: D018951:Antigens, CD20; D007075:Immunoglobulin M; D017730:Ki-1 Antigen