title: Synergistic effect of copper and lead uptake by fish.
abstract: Paracheirodon innesi was exposed (simultaneously or sequentially) to copper and lead in varying concentrations in a synthetic water solution. Metal accumulations in fish gills and the fish (without gills) were measured at the end of the exposure period. Results of the exposure experiment indicated that lead seems to facilitate the uptake of copper and vice versa when the exposure process is simultaneous. In the case of sequential exposure first to copper for 7 days then to lead for 20 days, lead accumulations in the fish and the gills were enhanced by copper, indicating a possible alteration of the physiological absorption process. The synergistic effects observed during either simultaneous or sequential exposure experiments can be described using logistic equations.
authors.affiliation: Department of Urban and Environmental Sciences, Peking University, Beijing, China.
authors.forename: S
authors.initials: S
authors.lastname: Tao
authors.forename: T
authors.initials: T
authors.lastname: Liang
authors.forename: J
authors.initials: J
authors.lastname: Cao
authors.forename: R W
authors.initials: RW
authors.lastname: Dawson
authors.forename: C
authors.initials: C
authors.lastname: Liu
mesh_terms: D000818:Animals; D001682:Biological Availability; D003300:Copper / Q000493:pharmacokinetics*; D004347:Drug Interactions; D005399:Fishes / Q000378:metabolism*; D007854:Lead / Q000493:pharmacokinetics*; D014018:Tissue Distribution; D014877:Water Pollution, Chemical
chemical_list: D007854:Lead; D003300:Copper