[Treatment of mild and moderate ulcerative colitis].
Selection of treatment for ulcerative colitis is based on the definition of clinical severity. In those medication is a main course. Mild and moderate cases are treated mainly with salicylazosulfapyridine or mesalazine. Patients with proctitis-type are added betamethazone suppositories and those with left-sided and total colitis-type predonisolone enema therapy simultaneously. If there is no response, they are given additional oral predonisolone. Even after remission, patients should be carefully observed. A good patient-physician relationship, continuation of maintenance therapy, and periodic follow-up examinations using colonoscopy or barium enema are essential to successful long-term management of this disease. Patients who have repeated relapsing should receive the stronger treatment, according to the endoscopic findings and clinical course in addition to the clinical severity.
Sakai
K
K
Third Department of Internal Medicine, Toho University.
Nakajima
S
S
Fujinuma
S
S
Sakai
Y
Y
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D001623:Betamethasone / Q000008:administration & dosage; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000628:therapy*; D004359:Drug Therapy, Combination; D004750:Enteral Nutrition; D005500:Follow-Up Studies; D006801:Humans; D019804:Mesalamine / Q000008:administration & dosage; D010288:Parenteral Nutrition; D011239:Prednisolone / Q000008:administration & dosage; D012720:Severity of Illness Index; D012460:Sulfasalazine / Q000008:administration & dosage
D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D012460:Sulfasalazine; D019804:Mesalamine; D001623:Betamethasone; D011239:Prednisolone