[Phospholipid composition of various parts of the involved organ in lung cancer].
Phospholipid spectrum of lung tissue fragments was studied in the dependence on the presence of malignant cells located at different distance from the focus of affection. Elevation of sphingomyelin (SM) level and lowering of phosphatidylcholine (PC) was noted in all analyzed patterns in pulmonary tissue. Alteration of growth malignant fields with extensive necrosis zones predominated in the same simples. The accumulation of phosphatidylinositol (PI) fraction and phosphatidylglycerol (PGL) deficiency was found. A similar tendency was supplemented with lysophosphatidylcholine (LPC) maximum on line of the extensive growth. It might be the result of invasive characteristic manifestation by tumor cells.
Khyshiktuev
B S
BS
Chita Medical Academy, Russia. bairk@hotmail.com
Agapova
Iu R
IuR
Zhilin
I V
IV
Ivanov
V N
VN
D000230:Adenocarcinoma / Q000378:metabolism* / Q000473:pathology; D018288:Carcinoma, Small Cell / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D008168:Lung / Q000378:metabolism* / Q000473:pathology; D008175:Lung Neoplasms / Q000378:metabolism* / Q000473:pathology; D009361:Neoplasm Invasiveness; D010743:Phospholipids / Q000378:metabolism*
D010743:Phospholipids