The great escape - AIDS viruses and immune control.
Many studies have been designed to address the role of CTL immune escape in HIV-1 infection, but have not given conclusive answers. Now, an elegant longitudinal analysis clearly demonstrates that progression to disease in SIV-infected macaques is associated with evasion of the CTL response (pages 1270-1276).
Goulder
P J
PJ
Walker
B D
BD
D000818:Animals; D018450:Disease Progression; D000939:Epitopes / Q000276:immunology; D016655:HIV Core Protein p24 / Q000276:immunology; D015497:HIV-1 / Q000276:immunology*; D008137:Longitudinal Studies; D008251:Macaca; D016097:Simian Acquired Immunodeficiency Syndrome / Q000276:immunology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*
D000939:Epitopes; D016655:HIV Core Protein p24