[Glucocorticoid treatment of ulcerative colitis].
Glucocorticoid is an important drug for ulcerative colitis. In this paper, the action mechanism of glucocorticoid, particularly that at molecular level in the cell, was mentioned. Mechanism in anti-inflammatory action, influence on cytokine production, immunosuppressive action and glucocorticoid resistance were reviewed.
Okawa
K
K
Department of Gastroenterology, Osaka City General Hospital.
Aoki
T
T
Oiya
H
H
Okuno
M
M
D001095:Arachidonic Acids / Q000378:metabolism; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D016207:Cytokines / Q000096:biosynthesis; D003864:Depression, Chemical; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008264:Macrophages / Q000187:drug effects / Q000276:immunology; D011965:Receptors, Glucocorticoid / Q000378:metabolism; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology
D001095:Arachidonic Acids; D016207:Cytokines; D005938:Glucocorticoids; D011965:Receptors, Glucocorticoid