title: Anti-Helicobacter pylori agents from the cashew apple.
abstract: Anacardic acids and (E)-2-hexenal characterized from the cashew Anacardium occidentale L. (Anacardiaceae) apple have been found to exhibit antibacterial activity against the Gram-negative bacterium Helicobacter pylori, which is now considered to cause acute gastritis. The same antibacterial compounds have also been found to inhibit urease (EC 3.5.1.5).
authors.affiliation: Department of Environmental Science, Policy and Management, University of California, Berkeley 94720-3112, USA.
authors.forename: J
authors.initials: J
authors.lastname: Kubo
authors.forename: J R
authors.initials: JR
authors.lastname: Lee
authors.forename: I
authors.initials: I
authors.lastname: Kubo
mesh_terms: D000447:Aldehydes / Q000302:isolation & purification* / Q000494:pharmacology; D048729:Anacardic Acids; D004791:Enzyme Inhibitors / Q000302:isolation & purification / Q000494:pharmacology; D016480:Helicobacter pylori / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D019685:Rosales / Q000737:chemistry*; D012459:Salicylates / Q000302:isolation & purification* / Q000494:pharmacology; D014510:Urease / Q000037:antagonists & inhibitors
chemical_list: D000447:Aldehydes; D048729:Anacardic Acids; D004791:Enzyme Inhibitors; D012459:Salicylates; C088115:anacardic acid; C051750:2-hexenal; D014510:Urease