Molecular cloning and tissue-specific expression of a new member of the regenerating protein family, islet neogenesis-associated protein-related protein.
Islet neogenesis-associated protein (INGAP) is a protein expressed during islet neogenesis. We have cloned a novel cDNA having a similar sequence to INGAP cDNA. The cDNA encodes 175 amino acids designated INGAP-related protein (INGAPrP). INGAP is expressed in cellophane-wrapped pancreas, but not in normal pancreas, whereas INGAPrP was abundantly expressed in normal pancreas.
Sasahara
K
K
Department of Pediatrics, School of Medicine, The University of Tokushima, Tokushima, Japan.
Yamaoka
T
T
Moritani
M
M
Yoshimoto
K
K
Kuroda
Y
Y
Itakura
M
M
D000209:Acute-Phase Proteins / Q000235:genetics; D000818:Animals; D000951:Antigens, Neoplasm; D001483:Base Sequence; D014408:Biomarkers, Tumor; D015152:Blotting, Northern; D002135:Calcium-Binding Proteins / Q000235:genetics*; D003001:Cloning, Molecular; D004386:Duodenum / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans; D037181:Lectins, C-Type; D051847:Lithostathine; D051379:Mice; D008969:Molecular Sequence Data; D018482:Muscle, Skeletal / Q000378:metabolism; D009419:Nerve Tissue Proteins; D009928:Organ Specificity / Q000235:genetics; D010179:Pancreas / Q000378:metabolism*; D000073718:Pancreatitis-Associated Proteins; D014176:Protein Biosynthesis; D011506:Proteins / Q000235:genetics*; D017386:Sequence Homology, Amino Acid
D000209:Acute-Phase Proteins; D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D002135:Calcium-Binding Proteins; D037181:Lectins, C-Type; D051847:Lithostathine; D009419:Nerve Tissue Proteins; D000073718:Pancreatitis-Associated Proteins; D011506:Proteins; C497617:REG1A protein, human; C000612141:REG3A protein, human; C497615:Reg1 protein, mouse; C490253:Reg3b protein, mouse