Replication of paramyxoviruses.
Molecular studies on the replication of paramyxoviruses have undergone a revolution in recent years due to the development of techniques that permit the manipulation of their genomes as cDNA. This has led to new information on the structure-function organization of the viral proteins involved in genome expression, as well as dissection of the cis-acting template sequences that regulate transcription and replication. Studies using recombinant viruses have also provided new insights into the role of the accessory proteins (V, C, M1/M2) in both for virus growth in cultured cells and pathogenesis in animals.
Curran
J
J
Department of Genetics and Microbiology, University of Geneva Medical School (CMU), Switzerland.
Kolakofsky
D
D
D010252:Paramyxoviridae / Q000235:genetics* / Q000502:physiology*; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism; D014779:Virus Replication
D014764:Viral Proteins