title: [Quantitative measurement of prefrontal lobe volume on three dimensional magnetic resonance imaging scan].
abstract: This article describes the measurement of the frontal and prefrontal lobe volumes on three dimensional (3-D) MRI in 13 children aged 5 months to 14 years and in 3 adults aged 27 to 39 years. The 3-D MRI data were acquired by the fast spoiled gradient recalled (SPGR) sequence using a 1.5 T MR imager. The frontal and prefrontal lobe volumes were measured by the volume measurement function of the Workstation. We confirmed that this technique to analyze segmental brain volumes achieved acceptable levels of reliability and accuracy. There was an increase in the frontal and prefrontal lobe volumes with advancing age, being rapid between 8 and 15 years of age. The prefrontal to frontal lobe volume ratio also increased gradually, with spurts between 8 and 15 years of age. This approach may be particularly useful for studies on patients with frontal and prefrontal lobe dysfunctions.
authors.affiliation: Department of Pediatrics, Yamanashi Medical University.
authors.forename: H
authors.initials: H
authors.lastname: Kanemura
authors.forename: M
authors.initials: M
authors.lastname: Aihara
authors.forename: S
authors.initials: S
authors.lastname: Aoki
authors.forename: K
authors.initials: K
authors.lastname: Hatakeyama
authors.forename: Y
authors.initials: Y
authors.lastname: Kamiya
authors.forename: C
authors.initials: C
authors.lastname: Ono
authors.forename: Y
authors.initials: Y
authors.lastname: Sata
authors.forename: S
authors.initials: S
authors.lastname: Nakazawa
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005625:Frontal Lobe / Q000033:anatomy & histology* / Q000254:growth & development; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007223:Infant; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015203:Reproducibility of Results