title: Obstructive nephropathy due to sulfa crystals in two HIV seropositive patients treated with sulfadiazine.
abstract: Two HIV seropositive patients receiving sulfadiazine for presumed cerebral toxoplasmosis who developed an obstructive nephropathy are described. Ultrasound examination showed respectively a bilateral hydro-ureteronephrosis in one patient and unilateral hydro-ureteronephrosis in the other. The obstructive nephropathy resolved in both patients with alkalic hydration and discontinuation of the sulfadiazine.
authors.affiliation: Institute of Tropical Medicine, Department of Clinical Sciences, Antwerp, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Colebunders
authors.forename: K
authors.initials: K
authors.lastname: Depraetere
authors.forename: E
authors.initials: E
authors.lastname: De Droogh
authors.forename: A
authors.initials: A
authors.lastname: Kamper
authors.forename: B
authors.initials: B
authors.lastname: Corthout
authors.forename: E
authors.initials: E
authors.lastname: Bottiau
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy*; D000468:Alkalies / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000009:adverse effects*; D003460:Crystallization; D005260:Female; D005440:Fluid Therapy; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D006869:Hydronephrosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D007669:Kidney Calculi / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D013411:Sulfadiazine / Q000009:adverse effects*; D016781:Toxoplasmosis, Cerebral / Q000188:drug therapy; D014463:Ultrasonography; D014515:Ureteral Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging
chemical_list: D000468:Alkalies; D000981:Antiprotozoal Agents; D013411:Sulfadiazine