Bowen's diseases and basal cell carcinomas in a patient.
Bowen's disease is a well-known precancerous lesion, in which invasive squamous carcinoma may develop. However, it is rare that Bowen's disease, basal cell carcinoma, and internal malignancy develop in a single patient. We report a case of a 54-year-old male patient with Bowen's disease, basal cell carcinoma of the skin, and squamous cell carcinoma of the lung. Multiple scaly erythematous patches had developed several years earlier and were diagnosed as Bowen's disease by skin biopsy. The number of lesions increased and, five months ago, a right lower lobectomy was done for squamous cell carcinoma which was detected on a chest X-ray. Skin biopsies of two different sites revealed Bowen's disease and basal cell carcinoma. The arsenic level was increased in his hair specimen. Cryotherapy was applied.
Kim
H J
HJ
Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Min
H G
HG
Lee
E S
ES
D001151:Arsenic / Q000032:analysis; D001707:Biopsy, Needle; D001913:Bowen's Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D002280:Basal Cell Carcinoma / Q000150:complications* / Q000175:diagnosis; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000175:diagnosis; D017679:Cryotherapy / Q000379:methods; D005500:Follow-Up Studies; D006197:Hair / Q000737:chemistry; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D016896:Treatment Outcome
D001151:Arsenic