title: What is evidence-based medicine?
abstract: BACKGROUND
  Three challenges that physicians and decision makers in the health care systems have to meet are a remarkable proportion of medical decisions without a sufficient base of scientific evidence, a slow and opaque process of integrating scientific knowledge into medical practice and a steadily decreasing half-life period of the medical knowledge.
  
  
  CONCLUSIONS
  During the last two decades, a number of projects have faced these problems and forced the development of evidence-based medicine (EBM). This concept claims the explicit conscientious use of current evidence from clinical research combined with the personal expertise in the process of medical decision making. The following article explains the main steps of practising and teaching EBM illustrated by a clinical example.
authors.affiliation: German Cochrane Centre, Department of Medical Informatics, University Hospital of Freiburg, Stefan-Meier-Str. 26, D-79104 Freiburg, Germany. mail@cochrane.de
authors.forename: G
authors.initials: G
authors.lastname: Antes
authors.forename: D
authors.initials: D
authors.lastname: Galandi
authors.forename: B
authors.initials: B
authors.lastname: Bouillon
mesh_terms: D016118:Anterior Cruciate Ligament / Q000601:surgery; D000070598:Anterior Cruciate Ligament Injuries; D003657:Decision Making; D004501:Education, Medical; D019317:Evidence-Based Medicine; D013502:General Surgery; D006801:Humans; D012107:Research Design