title: Evaluation of the use of calendar blister packaging on patient compliance with STD syndromic treatment regimens.
abstract: BACKGROUND
  Good compliance with antibiotic therapy is critical for successful management of sexually transmitted diseases (STDs).
  
  
  OBJECTIVE
  To evaluate the use of user-friendly drug packaging as a means of improving patient compliance with STD therapy and the acceptability of the packaging.
  
  
  METHODS
  Compliance of patients with STDs with treatment regimens for three different STD syndromes, using antibiotics packed in standard medicine packaging (SP), was compared to that of patients using calendar blister packaged drugs. Compliance was measured by counting the remaining pills at two return visits. Questionnaires were used to evaluate acceptability of the packs.
  
  
  RESULTS
  Compliance was significantly better among patients using the calendar blister packs than among those using standard packs, irrespective of dosing frequency. The degree of poor compliance increased with increasing dosing frequency. There was a high level of satisfaction with the blister pack among patients and health care workers.
  
  
  CONCLUSIONS
  Compliance can be improved by the introduction of user-friendly drug packaging, especially for more complex dosing regimens.
authors.affiliation: Sexually Transmitted Diseases Reference Centre, Johannesburg, South Africa.
authors.forename: J M
authors.initials: JM
authors.lastname: Wright
authors.forename: Y
authors.initials: Y
authors.lastname: Htun
authors.forename: M G
authors.initials: MG
authors.lastname: Leong
authors.forename: P
authors.initials: P
authors.lastname: Forman
authors.forename: R C
authors.initials: RC
authors.lastname: Ballard
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004349:Drug Packaging; D004359:Drug Therapy, Combination; D005069:Evaluation Studies as Topic; D006801:Humans; D008297:Male; D010342:Patient Acceptance of Health Care; D010349:Patient Compliance; D012749:Sexually Transmitted Diseases / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents