[Overall trypsin-like, elastase-like and antitryptic activity in patients with eye contusion].
The investigations of tear fluid of eye after contusion injury revealed on increase of trypsin-like activity in 1-3 day and 10-19 day after trauma, the progressively elevation of elastase-like activity and lowering of inhibitory potential along 2-3 week. It was detected indirect correlation between the elastase-like activity and severity of the contusion injury of the eye, the grade of corneal edema, corneal erosion and conjunctival wound, hyphema. This results was shown the participation and the role of proteolytic and inflammatory processes in pathogenesis of eye blunt trauma. It was establish that the during of local inflammation is 2 week end more and is necessary antiinflammatory therapy with use the proteases inhibitors.
Bendelik
E K
EK
Russian Medical Academy for Postgraduate Education, Moscow, Russia.
Dotsenko
V L
VL
Neshkova
E A
EA
Moshetova
L K
LK
Iarovaia
G A
GA
D003288:Contusions / Q000201:enzymology*; D005131:Eye Injuries / Q000201:enzymology*; D006801:Humans; D010196:Pancreatic Elastase / Q000378:metabolism*; D014357:Trypsin / Q000378:metabolism*; D014361:Trypsin Inhibitors / Q000378:metabolism*
D014361:Trypsin Inhibitors; D010196:Pancreatic Elastase; D014357:Trypsin