title: Remission of juvenile rheumatoid arthritis after infection with parvovirus B19.
abstract: A 22-year-old Caucasian woman with a 6 year history of persistently active, systemic onset juvenile rheumatoid arthritis (JRA) developed symptoms of headache, dry cough, nausea, vomiting, abdominal pain, diarrhea, and dehydration associated with a high fever, elevated liver enzymes, and lymphopenia. Subsequent investigation revealed acute infection with parvovirus B19. Following clinical improvement over 10-14 days solely with supportive care, her underlying disease remained in remission for about 7 months.
authors.affiliation: Division of Rheumatology, Hospital for Special Surgery and Cornell University Weil Medical College, New York, New York 10021, USA. batermanh@hss.edu
authors.forename: H E
authors.initials: HE
authors.lastname: Bateman
authors.forename: K A
authors.initials: KA
authors.lastname: Kirou
authors.forename: S A
authors.initials: SA
authors.lastname: Paget
authors.forename: M K
authors.initials: MK
authors.lastname: Crow
authors.forename: A M
authors.initials: AM
authors.lastname: Yee
mesh_terms: D000293:Adolescent; D001171:Arthritis, Juvenile / Q000150:complications / Q000503:physiopathology / Q000628:therapy* / Q000821:virology; D001691:Biological Therapy; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use; D010322:Parvoviridae Infections / Q000150:complications / Q000503:physiopathology*; D016732:Parvovirus B19, Human; D012074:Remission Induction
chemical_list: D008727:Methotrexate