title: [Acne and its treatment possibilities].
abstract: Acne is a multifactorial disease affecting the pilosebaceous follicles. It is a treatable condition for which the aims of therapy are to reduce social isolation and to prevent or minimise scarring. Propionibacterium acnes is an anaerobic bacterium strongly implicated in the pathogenesis of acne. A gradual increase in the resistance of P. acnes to many antibiotics has been documented in the last decade, and there is thus a growing need to use either appropriate antibiotics or even change the therapeutic strategy in favour of other regimens, i.e. isotretinoin, antiandrogens. A treatment guide is presented and the side-effects of these regimens are discussed.
authors.affiliation: Dermatologische Klinik, Universitätsspital Zürich. rboeni@derm.unizh.ch
authors.forename: R
authors.initials: R
authors.lastname: Böni
authors.forename: J
authors.initials: J
authors.lastname: Hafner
authors.forename: M
authors.initials: M
authors.lastname: Krasovec
mesh_terms: D000152:Acne Vulgaris / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy; D006801:Humans; D011425:Propionibacterium acnes
chemical_list: D000900:Anti-Bacterial Agents