[Renaissance of metformin].
Metformin structure and mechanisms of action were presented. Metformin plays a particularly important role in the treatment of diabetes mellitus type 2 by decreasing insulin resistance. Indications of its use include diabetes mellitus type 2 in obese patients without systemic complications or disordered blood supply in large body areas. It may be used as a monotherapy or combined with other oral drugs.
Sieradzki
J
J
D008078:Cholesterol, LDL / Q000187:drug effects; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D007333:Insulin Resistance; D008687:Metformin / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D009765:Obesity / Q000150:complications / Q000378:metabolism
D008078:Cholesterol, LDL; D008687:Metformin