Longithorols C-E. Three new macrocyclic sesquiterpene hydroquinone metabolites from the australian ascidian, aplidium longithorax
Chemical investigation of a Great Barrier Reef ascidian, Aplidium longithorax has resulted in the isolation of two new para-substituted cyclofarnesylated hydroquinone compounds, longithorols C (1) and D (2), and a novel macrocyclic chromenol, longithorol E (3). Longithorol C (1) had its absolute stereochemistry determined by the advanced Mosher method and all compounds had their structures determined by interpretation of spectroscopic data.
Davis
RA
Queensland Pharmaceutical Research Institute, Griffith University, Brisbane 4111, Australia.
Carroll
AR
Quinn
RJ