title: [Stenotrophomonas maltophilia endocarditis following mitral valve prosthesis implantation. Report of a case].
abstract: The authors report the first case of early postoperative endocarditis after mitral valvuloplasty due to Stenotrophomonas Maltophilia, a Gram negative organism, in a 37 year old man with no special risk factors. Pyrexia and mitral valve vegetations were the main features, and, in the absence of complications or of embolism, the patient was treated initially with triple antibiotherapy (ceftazidime, amikacine, ciprofloxacine). Relapse two weeks after withdrawal of treatment due to two variants of Stenotrophomas Maltophilia, one of which was resistant to ciprofloxacine, and the presence of a large vegetation, required repeat mitral valvuloplasty and a change in antibiotic therapy (ticarcilline with clavulanic acid, trimethoprim sulphamethoxazole, colistine). This time, the outcome was good. The little known Stenotrophomonas Maltophilia infectious endocarditis is a serious complication and, in the absence of standardised management, the authors suggest that, in view of the multi-resistant character of the organism and in the light of this case, surgery should be considered in association with prolonged antibiotic therapy.
authors.affiliation: Département de chirurgie cardiovasculaire, hôpital Broussais, Paris.
authors.forename: P
authors.initials: P
authors.lastname: Meimoun
authors.forename: J L
authors.initials: JL
authors.lastname: Mainardi
authors.forename: A
authors.initials: A
authors.lastname: Berrebi
authors.forename: J
authors.initials: J
authors.lastname: Choucair
authors.forename: P
authors.initials: P
authors.lastname: Chevalier
authors.forename: A
authors.initials: A
authors.lastname: Buu-Hoi
authors.forename: L
authors.initials: L
authors.lastname: Gutmann
authors.forename: A
authors.initials: A
authors.lastname: Carpentier
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000601:surgery; D020615:Stenotrophomonas maltophilia / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents