[The immunological changes caused by Mycobacterium tuberculosis in patients with different blood groups].
The distribution of blood groups of ABO system among 285 primary revealed persons with tuberculosis of the respiratory organs was studied. The condition of T-, B-link immunity and immunospecific reactivity depending on the patient group belonging was analyzed. A tendency to the increase in the number of persons with O(I) and B(III) and decrease in those with A(II) blood group among the examined ones comparatively with the data of the control group was determined. Considerable depression of proliferative activity of T-lymphocytes of sick persons with O(I) and B(III) and specific immunity of patients with O(I) in comparison with A(II) was revealed. Probably, this fact creates the favorable background for origination and development of tuberculosis infection and explains the increase of the number of persons with pulmonary tuberculosis which possess these phenotypical features.
Sybirna
R I
RI
Scientific-Research Institute of Epidemiology and Hygiene, Lviv, Ukraine.
Platonova
I L
IL
Sakhelashvili
M I
MI
D000017:ABO Blood-Group System / Q000276:immunology*; D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology; D001782:Blood Donors; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000276:immunology* / Q000382:microbiology
D000017:ABO Blood-Group System