Primary antiphospholipid syndrome with moyamoya-like vascular changes.
We describe a young girl with antiphospholipid syndrome (APS) and moyamoya-like cerebrovascular changes which reversed after anticoagulation. Although there was a risk of hemorrhage from collateral vessels, we speculate that this treatment may have prevented progression of the vascular abnormalities, while resolution of the thrombus resulted in improved cerebrovascular circulation.
Booth
F
F
Department of Pediatrics, University of Manitoba, Winnipeg, Manitoba, Canada.
Yanofsky
R
R
Ross
I B
IB
Lawrence
P
P
Oen
K
K
D017153:Antibodies, Anticardiolipin / Q000097:blood; D000925:Anticoagulants / Q000627:therapeutic use; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D002533:Cerebral Angiography; D002648:Child; D005260:Female; D006801:Humans; D009072:Moyamoya Disease / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D020521:Stroke / Q000150:complications; D014859:Warfarin / Q000627:therapeutic use
D017153:Antibodies, Anticardiolipin; D000925:Anticoagulants; D014859:Warfarin