title: [Hypersplenism: current status and perspectives].
abstract: The hypersplenism is a syndrome characterized by cytopenia (involving one or several cellular lines of peripheral blood), increased or normal medullar cellularity, elevated turnover of the involved cellular line. Several studies have emphasized the important role of the spleen as an immunocompetent organ, with a microcirculation and typical functional characteristics. The authors attempt to assess relations between the hypersplenism and splenomegaly, as well as indications, risks and complications of splenectomy in pathological conditions. Finally, the alternative procedures to splenectomy are described.
authors.affiliation: Dipartimento di Medicina Interna, Università, Messina.
authors.forename: C
authors.initials: C
authors.lastname: Musolino
authors.forename: L
authors.initials: L
authors.lastname: Calabrò
authors.forename: A
authors.initials: A
authors.lastname: Alonci
authors.forename: C
authors.initials: C
authors.lastname: Quartarone
authors.forename: G
authors.initials: G
authors.lastname: Bellomo
authors.forename: S
authors.initials: S
authors.lastname: Neri
authors.forename: V
authors.initials: V
authors.lastname: Rizzo
authors.forename: F
authors.initials: F
authors.lastname: Pernice
authors.forename: N
authors.initials: N
authors.lastname: Frisina
mesh_terms: D000279:Administration, Cutaneous; D003937:Diagnosis, Differential; D004621:Embolization, Therapeutic; D006801:Humans; D006971:Hypersplenism / Q000175:diagnosis / Q000628:therapy; D009829:Oleic Acids / Q000008:administration & dosage; D012597:Sclerosing Solutions / Q000008:administration & dosage; D013156:Splenectomy; D013157:Splenic Artery; D013163:Splenomegaly / Q000175:diagnosis
chemical_list: D009829:Oleic Acids; D012597:Sclerosing Solutions; C033343:ethanolamine oleate