title: [Neurocardiogenic syncope in children].
abstract: Between december of 1994 and june 1997, 90 children and adolescents were referred to the Shaio Clinic Foundation for evaluation of recurrent unexplained syncope. Head-up tilt testing was positive in 45 (50%), 23 male, with a mean age of 12.7 years (range 5-17 years). The response during Head-up tilt testing was predominantly vasodepressor (57%), followed by mixed in 24% and cardioinhibitory in the remaining 17%. The majority of patients had a positive response during pharmacological phase with isoproterenol infusion at a mean time of 17 +/- 8 minutes. Head-up tilt is a safe diagnostic test and defines the cause of unexplained syncope in up to 50% of children and young adults with recurrent syncope. The management was based on education, control of risk factors and psychological and/or physical rehabilitation. In the 15.2 months follow up we observed complete remission or a significant reduction of symptoms in 95% of the cases. Only 5% of the patients persisted or had worsening of their symptoms.
authors.affiliation: Fundación Clínica Shaio, Bogotá, Colombia.
authors.forename: V M
authors.initials: VM
authors.lastname: Velasco
authors.forename: F
authors.initials: F
authors.lastname: Rosas
authors.forename: J F
authors.initials: JF
authors.lastname: López
authors.forename: G
authors.initials: G
authors.lastname: Carrillo
authors.forename: G
authors.initials: G
authors.lastname: Cassalett
authors.forename: S
authors.initials: S
authors.lastname: Slotkus
mesh_terms: D000293:Adolescent; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D001919:Bradycardia / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007022:Hypotension / Q000503:physiopathology; D007545:Isoproterenol / Q000627:therapeutic use; D008297:Male; D012307:Risk Factors; D019462:Syncope, Vasovagal / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology*; D013610:Tachycardia / Q000503:physiopathology
chemical_list: D000318:Adrenergic beta-Agonists; D007545:Isoproterenol