Surgical treatment of Parkinson's disease.
Ablative surgery and deep brain stimulation for Parkinson's disease can be performed in the thalamus, the pallidum and the subthalamic nucleus. The efficacy and safety of unilateral pallidotomy is well established. Deep brain stimulation has a lower morbidity and is preferred for bilateral surgery. The subthalamic nucleus presently seems to be the most promising target in advanced stage Parkinson's disease.
Krack
P
P
Neurology Department, University of Kiel, Germany. p.krack@neurologie.uni-kiel.de
Hamel
W
W
Mehdorn
H M
HM
Deuschl
G
G
D004558:Electric Stimulation / Q000379:methods; D005917:Globus Pallidus / Q000502:physiology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D010300:Parkinson Disease / Q000473:pathology / Q000601:surgery*; D020531:Subthalamic Nucleus / Q000502:physiology / Q000601:surgery*; D013788:Thalamus / Q000601:surgery*