title: [Elimination of CD28+ T cell in patients with chronic active hepatitis].
abstract: OBJECTIVE
  To study the role of toxicyte T cell in active hepatitis.
  
  
  METHODS
  We examined CD28+ T cell in patients with chronic active/remission hepatitis by flow cytometry.
  
  
  RESULTS
  It shows that CD28+, CD8+CD28+ T cell in patients with chronic active hepatitis decreased significantly, compared with normal control or patients with liver cirrhosis and heptoma.
  
  
  CONCLUSIONS
  It implies that B7-CD28 costimulation pathway contribute to the tissue injury in hepatitis.
authors.affiliation: Clinical Immunology Center, Changzheng Hospital, Shanghai.
authors.forename: A
authors.initials: A
authors.lastname: Deng
authors.forename: R
authors.initials: R
authors.lastname: Zhong
authors.forename: S
authors.initials: S
authors.lastname: Chen
mesh_terms: D018106:CD28 Antigens / Q000032:analysis*; D006521:Hepatitis, Chronic / Q000276:immunology*; D006801:Humans; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D018106:CD28 Antigens