title: [Massive feto-maternal transfusion. Report of 3 cases with review of the literature].
abstract: Massive feto maternal hemorrhage is rare. Early diagnosis is important because massive feto-maternal hemorrhage has a poor prognosis. The clinical manifestations of transplacental hemorrhage are related not only to the size of the hemorrhage but also to the time at which the hemorrhage occurs. In women who are candidates for Rh immune prophylaxis, massive feto maternal hemorrhage may be detected by Kleihauer test and we suggest that 10 micrograms dose of immune globin should be administered for each estimated ml of Rh positive blood given, to prevent an immunization Disappearance of fetal cells by Kleihauer test or appearance residual antibody suggests the adequacy of therapy. Three cases of massive fetomaternal hemorrhage (more than 225 ml) are presented here. Two mothers was Rh negative and they are delivered of rhésus positive children, which necessitated the administration of large volume of anti D. One of the cases shows the possibility of association between choriocarcinoma and positive kleihauer test.
authors.affiliation: Service de Gynécologie-Obstétrique II, Hôpital de Hautepierre, Strasbourg.
authors.forename: E
authors.initials: E
authors.lastname: Boudier
authors.forename: B
authors.initials: B
authors.lastname: Langer
authors.forename: C
authors.initials: C
authors.lastname: Martinez
authors.forename: M
authors.initials: M
authors.lastname: Schumpp
authors.forename: A
authors.initials: A
authors.lastname: Treisser
authors.forename: G
authors.initials: G
authors.lastname: Schlaeder
mesh_terms: D000328:Adult; D002822:Choriocarcinoma / Q000150:complications; D005260:Female; D005331:Fetomaternal Transfusion / Q000150:complications; D006801:Humans; D011247:Pregnancy; D012203:Rh Isoimmunization; D014594:Uterine Neoplasms / Q000150:complications