title: Bilateral substantia nigra changes on MRI in a patient with encephalitis lethargica.
abstract: A 33-year-old woman admitted for meningoencephalitis had features of encephalitis lethargica develop on her third day of illness. She had ophthalmoplegia, akinetic mutism, and prominent extrapyramidal signs consisting of lip and hand tremors, cogwheel rigidity, and facial bradykinesia.
authors.affiliation: Department of Neurology, National Neuroscience Institute,Republic of Singapore, Singapore.
authors.forename: L N
authors.initials: LN
authors.lastname: Kun
authors.forename: S Y
authors.initials: SY
authors.lastname: Yian
authors.forename: L S
authors.initials: LS
authors.lastname: Haur
authors.forename: H
authors.initials: H
authors.lastname: Tjia
mesh_terms: D000208:Acute Disease; D000328:Adult; D000405:Akinetic Mutism / Q000150:complications; D004660:Encephalitis / Q000150:complications / Q000175:diagnosis*; D005116:Extrapyramidal Tracts / Q000503:physiopathology; D005152:Facial Muscles / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009127:Muscle Rigidity / Q000150:complications; D009135:Muscular Diseases / Q000150:complications / Q000503:physiopathology; D009886:Ophthalmoplegia / Q000150:complications; D013378:Substantia Nigra / Q000473:pathology*; D014202:Tremor / Q000150:complications