title: Effect of the levonorgestrel-releasing intrauterine system on uterine myomas in a renal transplant patient.
abstract: The levonorgestrel-releasing intrauterine system (LNG-IUS) has been used in the treatment of both idiopathic menorrhagia and adenomyosis. An electronic search of the on-line medical literature revealed no reports of its use for menorrhagia secondary to uterine myomas. Presented here is the successful treatment of uterine myomas with menorrhagia in a woman with a renal transplant. There was a significant reduction in menorrhagia, dysmenorrhea, and uterine and myoma size with the use of the LNG-IUS. We believe that this system provides an alternative to conventional hysterectomy and gonadotrophin-releasing hormonal analog medical treatment for uterine myomas, with a possibly inhibitory effect on myoma growth.
authors.affiliation: Department of Obstetrics and Gynaecology, National University Hospital, Singapore.
authors.forename: Y F
authors.initials: YF
authors.lastname: Fong
authors.forename: K
authors.initials: K
authors.lastname: Singh
mesh_terms: D000328:Adult; D001803:Blood Transfusion; D003271:Contraceptive Agents, Female / Q000008:administration & dosage*; D004412:Dysmenorrhea / Q000188:drug therapy; D005260:Female; D006397:Hematinics / Q000627:therapeutic use; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007436:Intrauterine Devices, Medicated; D016030:Kidney Transplantation / Q000502:physiology; D007889:Leiomyoma / Q000188:drug therapy / Q000503:physiopathology*; D016912:Levonorgestrel / Q000008:administration & dosage*; D008595:Menorrhagia / Q000188:drug therapy; D010053:Ovary / Q000000981:diagnostic imaging; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000188:drug therapy / Q000503:physiopathology*; D014599:Uterus / Q000000981:diagnostic imaging
chemical_list: D003271:Contraceptive Agents, Female; D006397:Hematinics; D006454:Hemoglobins; D016912:Levonorgestrel