Biomarkers as early predictors of long-term health status and human immune function.
A central issue that must be addressed by phytonutrient research is how to assess the effects of phytonutrients on long-term health. Proper assessment of these effects requires the measurement of biomarkers of long-term health in people consuming any particular phytonutrient. This is a brief review of what is known about biomarkers of cancer risk, immune function, and aging. Relatively few biomarkers of long-term health have been even partially validated in experimental animals or people.
Bronson
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Antioxidants Research Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA.
Birt
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Meydani
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D000375:Aging / Q000502:physiology; D000818:Animals; D015415:Biomarkers; D006304:Health Status; D006801:Humans; D007107:Immune System / Q000502:physiology; D009369:Neoplasms; D010940:Plant Proteins / Q000502:physiology* / Q000627:therapeutic use; D011315:Preventive Medicine; D012106:Research; D012306:Risk; D014481:United States
D015415:Biomarkers; D010940:Plant Proteins