Hemolytic-uremic syndrome with involvement of basal ganglia and cerebellum.
Hemolytic-uremic syndrome is a microangiopathy often associated with neurologic symptoms. Several patients with persistent lesions in cerebrum and basal ganglia have been reported. We present two children with bilateral basal ganglia and additional unilateral cerebellar lesions in magnetic resonance imaging. These resolved completely in one child. In the other child there were still residuals after 11 weeks. The neurologic symptoms of both improved after several therapeutic plasma exchanges and disappeared after months.
Hager
A
A
Kinderklinik der TU München, Germany.
Staudt
M
M
Klare
B
B
von Einsiedel
H G
HG
Krägeloh-Mann
I
I
D001479:Basal Ganglia / Q000473:pathology; D001480:Basal Ganglia Diseases / Q000175:diagnosis*; D002526:Cerebellar Diseases / Q000175:diagnosis*; D002531:Cerebellum / Q000473:pathology; D002675:Child, Preschool; D004292:Dominance, Cerebral / Q000502:physiology; D005500:Follow-Up Studies; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination