title: [Urinary tract infection in an urban population: etiology and antibiotic sensitivity as a function of patient history].
abstract: OBJECTIVE
  The aim of this study was to explore the relationship between etiological factors, bacterial isolates and Escherichia coli susceptibility to antibiotics in ambulatory patients with urinary tract infection.
  
  
  METHODS
  A prospective study was conducted in 13 private medical laboratories in France in March 1998. Data were collected on 658 cases involving 679 strains in ambulatory patients with urinary tract infections. Data on age, gender, catheter insertion within the 7 preceding days, and history of hospitalization, urinary infection and antibiotic treatment during the 6 preceding months were recorded. The distribution of the bacterial isolates and Eschericha coli sensitivity to ciprofloxacin, cotrimoxazole, and gentamycin were studied.
  
  
  RESULTS
  E. coli was most frequently isolated in women, in patients with no catheter or without a history of antibiotic treatment, hospitalization or urinary infection. There was no difference in E. coli sensitivity according to sex and age in women. In patients with prior antibiotic treatment, all the tested antibiotics except gentamycin were significantly less active. In case of prior hospitalization, the E. coli isolates were more resistant to amoxicillin, quinolones, cotrimoxazole and gentamycin. The level of E. coli suceptibility rose as the delay since hospitalization or urinary infection increased.
  
  
  CONCLUSIONS
  Ambulatory patients comprise a heterogeneous population requiring particular attention to correctly adapt therapeutic strategies.
authors.affiliation: Laboratoire Claude Bernard (AFORCOPI-BIO), HIA Begin, Saint-Mandé.
authors.forename: D
authors.initials: D
authors.lastname: De Mouy
authors.forename: J D
authors.initials: JD
authors.lastname: Cavallo
authors.forename: M
authors.initials: M
authors.lastname: Armengaud
authors.forename: J P
authors.initials: JP
authors.lastname: Arzouni
authors.forename: J L
authors.initials: JL
authors.lastname: Berges
authors.forename: J P
authors.initials: JP
authors.lastname: Bouilloux
authors.forename: N
authors.initials: N
authors.lastname: Charbit
authors.forename: N
authors.initials: N
authors.lastname: Cirioni
authors.forename: R
authors.initials: R
authors.lastname: Fabre
authors.forename: E
authors.initials: E
authors.lastname: Garrabe
authors.forename: J
authors.initials: J
authors.lastname: Galinier
authors.forename: A
authors.initials: A
authors.lastname: Gayon
authors.forename: F
authors.initials: F
authors.lastname: Grobost
authors.forename: G
authors.initials: G
authors.lastname: Larribet
authors.forename: J P
authors.initials: JP
authors.lastname: Lepargneur
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004352:Drug Resistance, Microbial; D004927:Escherichia coli Infections / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012744:Sex Ratio; D014505:Urban Population; D014552:Urinary Tract Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents