[Morphofunctional characteristics of rat thyroid gland under the combined effect of oxytocin and adrenaline].
The influence of oxytocin, adrenalin and their combination on rat thyroid gland was studied after intraperitoneal administration of these hormones and following incubation of thyroid gland fragments in media, containing the neurohormones. Thyrostimulating effect of oxytocin (increase in thyrocyte height and 3H-leucine incorporation) was demonstrated in in vivo and in vitro experiments. Adrenaline did not cause morphofunctional changes in thyrocytes although it suppresses oxytocin thyrostimulating effect when administered simultaneously with it in both in vivo and in vitro experiments.
Makina
D M
DM
Laboratory of Neuroendocrinology, I.M. Sechenov Institute of Evolutional Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg.
Krasnovskaia
I A
IA
D000818:Animals; D001345:Autoradiography; D004837:Epinephrine / Q000494:pharmacology*; D007274:Injections, Intraperitoneal; D008297:Male; D010121:Oxytocin / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D013268:Stimulation, Chemical; D013961:Thyroid Gland / Q000166:cytology / Q000187:drug effects*
D010121:Oxytocin; D004837:Epinephrine