title: Numerical simulation of the pulsating catheter pump: A left ventricular assist device.
abstract: The pulsating catheter (PUCA) pump, a left ventricular assist device, consists of a hydraulically or pneumatically driven membrane pump, extracorporeally placed and mounted to a valved catheter. The catheter is introduced into an easily accessible artery and positioned with its distal tip in the left ventricle. Blood is aspirated from the left ventricle during systole and ejected into the ascending aorta during diastole. A numerical model of the PUCA pump has been developed to determine the internal diameter of the PUCA pump catheter that allows a certain blood flow. The model considers a limitation of mechanical blood damage and determines the accompanying pressure and flow profile for driving the pump. For a flow of 5 L/min, a catheter with an internal diameter of at least 6. 95 mm is required. For 3 L/min, the minimal diameter is 5.50 mm. The latter catheter can be introduced in the axillary artery, the former via the aorta during an open thorax surgical procedure. To validate the numerical model, 2 different PUCA pump configurations were tested in vitro. Results showed a good resemblance between model and in vitro behavior of the PUCA pump.
authors.affiliation: Division of Artificial Organs, Faculty of Medical Sciences, University of Groningen, The Netherlands.
authors.forename: G J
authors.initials: GJ
authors.lastname: Verkerke
authors.forename: D
authors.initials: D
authors.lastname: Mihaylov
authors.forename: A A
authors.initials: AA
authors.lastname: Geertsema
authors.forename: J
authors.initials: J
authors.lastname: Lubbers
authors.forename: G
authors.initials: G
authors.lastname: Rakhorst
mesh_terms: D001011:Aorta; D001366:Axillary Artery; D001794:Blood Pressure; D006328:Cardiac Catheterization / Q000295:instrumentation; D002302:Cardiac Output; D004867:Equipment Design; D006353:Heart-Assist Devices; D006801:Humans; D008567:Membranes, Artificial; D008955:Models, Cardiovascular; D011673:Pulsatile Flow; D015203:Reproducibility of Results; D012212:Rheology; D013318:Stroke Volume; D013499:Surface Properties; D016277:Ventricular Function, Left; D017725:Ventricular Pressure
chemical_list: D008567:Membranes, Artificial