[Barrett's esophagus and antireflux surgery: a study of a series of 26 patients].
OBJECTIVE
The aim of this study was to report the results of a retrospective series of 26 patients with Barrett's esophagus treated by antireflux surgery.


METHODS
From 1979 to 1998, 21 men and five women (mean age: 53 years) with histologically proven Barrett's esophagus underwent an antireflux procedure. The mean length of Barrett's epithelium was 5.9 cm for 19 patients (73.1%). Six patients (23.1%) had tongue lesions of Barrett's epithelium, and one (3.8%) had ectopic gastric mucosa. None of the patients had a preoperative esophageal biopsy that revealed high-grade dysplasia or carcinoma. Laparotomy was performed in 17 cases and laparoscopy in nine cases. Preoperative endoscopic local treatment with argon coagulation was performed in one patient.


RESULTS
Clinical mean follow-up was 78 months and endoscopic mean follow-up was 59.3 months. No increase in the length of the Barrett's epithelium was observed. Seven patients (27%) had complete or partial regression (among them three patients with tongue lesions and one patient preoperatively treated by argon). No patients developed high-grade dysplasia or carcinoma.


CONCLUSIONS
Regression of Barrett's esophagus is possible but not frequent and unpredictable after antireflux procedure. However, endoscopic and histological surveillance should be continued postoperatively.
Baulieux
J
J
Service de chirurgie et de la transplantation hépatique, hôpital de la Croix-Rousse, Lyon, France.
Mabrut
J Y
JY
Ducerf
C
C
Adham
M
M
de la Roche
E
E
Berthoux
N
N
Bourdeix
O
O
Gaudin
J L
JL
Souquet
J C
JC
D000328:Adult; D000368:Aged; D001471:Barrett Esophagus / Q000473:pathology* / Q000628:therapy; D002828:Choristoma / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D004945:Esophagoscopy; D005260:Female; D005500:Follow-Up Studies; D018662:Fundoplication; D005753:Gastric Mucosa / Q000473:pathology; D005764:Gastroesophageal Reflux / Q000601:surgery; D006801:Humans; D010535:Laparoscopy; D007813:Laparotomy; D017075:Laser Coagulation; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D012189:Retrospective Studies; D014060:Tongue Diseases / Q000473:pathology