title: The use of a semi-customized phantom for verification of conformal plans.
abstract: We have developed a technique for inverse treatment planning of prostate therapy designed to improve the degree of conformation between the dose distribution and the target volume. We compared the inverse plan with a "standard" four-field box technique as well as a four-field technique using oblique fields ("cross technique"). We validated the dosimetry of the inverse plan using Fricke gel solution in phantom specifically designed for this purpose. The phantom is a Plexiglas tank with a cross section, which approximates the dimensions of the pelvis. Anatomical data from computed tomography (CT) images of a patient were used to simulate organs in our phantom. This allows us to calculate dose distributions with the external geometry of the phantom and internal anatomy of the patient. Dose-volume histograms (DVHs) for the three different plans were calculated. The phantom containing the Fricke gel was irradiated according to the inverse plan. Magnetic resonance (MR) images was used to determine the dose distribution delivered to the phantom. We observe, on DVHs, that the inverse plan significantly reduces the dose to the rectum and the bladder but slightly increases the inhomogeneity inside the target volume. Correlation is good between isodoses on MR images and calculated isodoses. We conclude that inverse planning software can greatly improve the conformal degree of treatment to the prostate. This technique could be applied to other complex anatomic sites at which dose to organs at risk is a limiting factor and increased dose to the target volume is indicated. Our phantom and the Fricke gel solution are convenient to carry out validation of conformal treatments.
authors.affiliation: CHU de Grenoble, Service d'Oncologie-Radiothérapie, Grenoble, France. Jean-Yves.Giraud@uif-grenoble.fr
authors.forename: J Y
authors.initials: JY
authors.lastname: Giraud
authors.forename: C
authors.initials: C
authors.lastname: Cohard
authors.forename: A
authors.initials: A
authors.lastname: Dusserre
authors.forename: P
authors.initials: P
authors.lastname: Vassal
authors.forename: M
authors.initials: M
authors.lastname: Bolla
authors.forename: J
authors.initials: J
authors.lastname: Troccaz
authors.forename: P
authors.initials: P
authors.lastname: Cinquin
authors.forename: Y
authors.initials: Y
authors.lastname: Menguy
authors.forename: S
authors.initials: S
authors.lastname: Grand
authors.forename: F
authors.initials: F
authors.lastname: Esteve
authors.forename: J F
authors.initials: JF
authors.lastname: Lebas
mesh_terms: D006801:Humans; D008297:Male; D019047:Phantoms, Imaging; D011467:Prostate / Q000528:radiation effects; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D020266:Radiotherapy, Conformal; D012007:Rectum / Q000528:radiation effects; D001743:Urinary Bladder / Q000528:radiation effects