title: Congenital myotonic myopathy in the miniature schnauzer: an autosomal recessive trait.
abstract: Myotonia is a clinical sign characterized by a delay in skeletal muscle relaxation following electrical or mechanical stimulation. A series of related miniature schnauzer dogs with congenital myotonic myopathy were studied. A composite pedigree of six affected litters and the results of a planned breeding between two affected animals are consistent with an autosomal recessive mode of inheritance.
authors.affiliation: Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104, USA. vite@vet.upenn.edu
authors.forename: C H
authors.initials: CH
authors.lastname: Vite
authors.forename: J
authors.initials: J
authors.lastname: Melniczek
authors.forename: D
authors.initials: D
authors.lastname: Patterson
authors.forename: U
authors.initials: U
authors.lastname: Giger
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000151:congenital / Q000235:genetics*; D004285:Dogs; D005260:Female; D008297:Male; D020967:Myotonic Disorders / Q000151:congenital / Q000235:genetics / Q000662:veterinary*; D010375:Pedigree