title: Dose-response of seeds of the parasitic weeds Striga and Orobanche toward the synthetic germination stimulants GR 24 and Nijmegen 1.
abstract: Striga and Orobanche seeds germinate in response to a host-derived germination stimulant. Dose-response curves of the synthetic strigolactone analogues GR 24 and Nijmegen 1 were determined, and their activities were compared to that of the naturally occurring stimulant sorgolactone. Typical sigmoidal curves were obtained. ED(50) values for GR 24 were in the order of 10(-)(9)-10(-)(8) mol/L; for Nijmegen 1 these values were 3 orders of magnitude higher. Both synthetic stimulants are appreciably active at low concentrations and merit investigation as agents for the suicidal germination approach (i.e., treatment of the soil with stimulant in the absence of a host).
authors.affiliation: Department of Organic Chemistry, NSR Center for Molecular Structure, Design and Synthesis, University of Nijmegen, The Netherlands.
authors.forename: S C
authors.initials: SC
authors.lastname: Wigchert
authors.forename: E
authors.initials: E
authors.lastname: Kuiper
authors.forename: G J
authors.initials: GJ
authors.lastname: Boelhouwer
authors.forename: G H
authors.initials: GH
authors.lastname: Nefkens
authors.forename: J A
authors.initials: JA
authors.lastname: Verkleij
authors.forename: B
authors.initials: B
authors.lastname: Zwanenburg
mesh_terms: D004305:Dose-Response Relationship, Drug; D007783:Lactones / Q000378:metabolism / Q000494:pharmacology*; D010937:Plant Growth Regulators / Q000494:pharmacology*; D010944:Plants / Q000187:drug effects*; D012639:Seeds / Q000187:drug effects / Q000502:physiology*
chemical_list: D007783:Lactones; D010937:Plant Growth Regulators; C412302:nijmegen 1