[Unexpected regeneration of a congenital unilateral hypoplastic- dysplastic kidney after a contralateral nephrectomy for Wilms tumor].
The congenital hypoplastic-dysplastic kidney is characterized by a significant reduction of renal mass, an abnormal parenchymal differentiation and is associated with anomalies of the whole urinary tract. Not much is known about the ability for regeneration in such a kidney. We report on a 2 year 11 months old boy with an anaplastic Wilms tumor of the left kidney, in whom after tumor-nephrectomy an unexpected functional and sonographically documented morphological regeneration of the contralateral hypoplastic-dysplastic kidney occurred. The regeneration of this kidney is especially notable, because it occurred during nephrotoxic chemotherapy and radiotherapy.
Kager
L
L
St. Anna Kinderspital, Wien.
Schroth
B
B
Amann
G
G
Zoubek
A
A
Wiesbauer
P
P
Horcher
E
E
Dieckmann
K
K
Gadner
H
H
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D006801:Humans; D007668:Kidney / Q000002:abnormalities* / Q000187:drug effects / Q000502:physiology* / Q000601:surgery; D007677:Kidney Function Tests; D007680:Kidney Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D008297:Male; D009392:Nephrectomy; D020127:Recovery of Function; D012038:Regeneration / Q000187:drug effects / Q000502:physiology* / Q000528:radiation effects; D016896:Treatment Outcome; D009396:Wilms Tumor / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery