title: Use of sevoflurane inhalation sedation for outpatient third molar surgery.
abstract: This study attempted to determine if sevoflurane in oxygen inhaled via a nasal hood as a sole sedative agent would provide an appropriate level of deep sedation for outpatient third molar surgery. Twenty-four patients scheduled for third molar removal were randomly assigned to receive either nasal hood inhalation sevoflurane or an intravenous deep sedation using midazolam and fentanyl followed by a propofol infusion. In addition to measuring patient, surgeon, and dentist anesthesiologist subjective satisfaction with the technique, physiological parameters, amnesia, and psychomotor recovery were also assessed. No statistically significant difference was found between the sevoflurane and midazolam-fentanyl-propofol sedative groups in physiological parameters, degree of amnesia, reported quality of sedation, or patient willingness to again undergo a similar deep sedation. A trend toward earlier recovery in the sevoflurane group was identified. Sevoflurane can be successfully employed as a deep sedative rather than a general anesthetic for extraction of third molars in healthy subjects.
authors.affiliation: Ohio State University, College of Dentistry, Columbus 43210, USA. ganzberg.1@osu.edu
authors.forename: S
authors.initials: S
authors.lastname: Ganzberg
authors.forename: J
authors.initials: J
authors.lastname: Weaver
authors.forename: F M
authors.initials: FM
authors.lastname: Beck
authors.forename: G
authors.initials: G
authors.lastname: McCaffrey
mesh_terms: D000293:Adolescent; D000328:Adult; D000766:Anesthesia, Dental; D019162:Anesthetics, Combined; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D016292:Procedural Sedation; D005260:Female; D005283:Fentanyl; D006801:Humans; D006993:Hypnotics and Sedatives; D008297:Male; D008738:Methyl Ethers; D008874:Midazolam; D008964:Molar, Third / Q000601:surgery*; D009609:Nitrous Oxide; D010865:Pilot Projects; D015742:Propofol; D000077149:Sevoflurane; D011795:Surveys and Questionnaires; D014081:Tooth Extraction
chemical_list: D019162:Anesthetics, Combined; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D006993:Hypnotics and Sedatives; D008738:Methyl Ethers; D000077149:Sevoflurane; D009609:Nitrous Oxide; D008874:Midazolam; D005283:Fentanyl; D015742:Propofol