Rare incidence of interspousal transmission of Helicobacter pylori in asymptomatic individuals in Japan.
PCR-restriction fragment length polymorphism electrophoretic patterns of amplified ureB and ureC of Helicobacter pylori were compared between spouses after digestion with restriction endonucleases. Twenty of 21 couples, both members of which were positive for H. pylori, showed ureB and ureC patterns that differed between spouses. We concluded that in Japan, interspousal transmission of H. pylori occurs rarely.
Suzuki
J
J
Department of Internal Medicine IV, University of Tokyo School of Medicine, Tokyo 112-8688, Japan.
Muraoka
H
H
Kobayasi
I
I
Fujita
T
T
Mine
T
T
D005260:Female; D005798:Genes, Bacterial; D016481:Helicobacter Infections / Q000382:microbiology / Q000635:transmission*; D016480:Helicobacter pylori / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D018454:Spouses; D014510:Urease / Q000235:genetics
D014510:Urease