Prebiotic formation of ADP and ATP from AMP, calcium phosphates and cyanate in aqueous solution.
Adenosine-5'-triphosphate was synthesized by the phosphorylation of adenosine-5'-diphosphate in aqueous solution containing cyanate as a condensing reagent and insoluble calcium phosphate produced from phosphate and calcium chloride. In a similar manner, adenosine-5'-diphosphate was synthesized from adenosine-5'-monophosphate. When the experiment was carried out in the conditions of 4 degrees C and pH 5.75, the formation of adenosine-5'-diphosphate and adenosine-5'-triphosphate from adenosine-5'-monophosphate was observed in the yields of 19 and 7%, respectively. The other nucleoside-5'-triphosphates were also produced from their respective diphosphates.
Yamagata
Y
Y
Laboratory of Chemical Evolution, Ishikawa, Japan. yamagata@shift.ne.jp
D000244:Adenosine Diphosphate / Q000138:chemical synthesis; D000249:Adenosine Monophosphate; D000255:Adenosine Triphosphate; D000327:Adsorption; D002130:Calcium Phosphates; D002851:Chromatography, High Pressure Liquid; D003485:Cyanates; D006863:Hydrogen-Ion Concentration; D010766:Phosphorylation; D012996:Solutions
D002130:Calcium Phosphates; D003485:Cyanates; D012996:Solutions; D000249:Adenosine Monophosphate; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate