[Molecular-epidemiological characteristics of basic foci of the HIV epidemic among substance abusers in Russia].
A serological test has been developed, allowing a rapid and reliable differentiation between envA and envB genotypes in the sera from HIV-1-infected IDUs and their sexual partners. We analyzed 556 specimens from HIV-1-seropositive IDUs and their sexual partners. The sera were collected in five regions of Russia with the greatest number of HIV-1-infected IDUs. High homogeneity of HIV-1 in each of the regions was observed. In Tver, Rostov-on-Don, Nizhny Novgorod, and Krasnodar 100% sera tested belonged to the env subtype A. All the patients from the Kalinigrad region were infected with the env subtype B virus, which is apparently a recombinant.
Bobkova
M R
MR
Bobkov
A F
AF
Buravtsova
E V
EV
Selimova
L M
LM
Kazennova
E V
EV
Kolesnik
A N
AN
Perekhodchenko
E N
EN
Saukhat
S R
SR
Momot
O F
OF
Moshkovich
G F
GF
D015686:Gene Products, env / Q000235:genetics; D005838:Genotype; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology* / Q000821:virology; D015497:HIV-1 / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D017720:Molecular Epidemiology; D012426:Russia / Q000453:epidemiology; D012747:Sexual Partners; D015819:Substance Abuse, Intravenous / Q000150:complications*
D015686:Gene Products, env