title: Structure of the arginase coding gene and its transcript in Aspergillus nidulans.
abstract: The arginase structural gene (agaA) from Aspergillus nidulans has been cloned and characterised. Depending on the growth conditions of the mycelium, transcripts of this gene have different 5'ends. These differences could result either from the presence of multiple transcription initiation sites or from differential processing of mRNA. The agaA mRNA has a long 5'UTR with a potentially complex secondary structure. Putative arginine binding aptamers were found in this UTR suggesting interesting possibilities for regulation of the agaA expression.
authors.affiliation: Department of Genetics, University of Warsaw and Institute of Biochemistry and Biophysics Polish Academy of Science, Warszawa.
authors.forename: P
authors.initials: P
authors.lastname: Borsuk
authors.forename: A
authors.initials: A
authors.lastname: Dzikowska
authors.forename: J
authors.initials: J
authors.lastname: Empel
authors.forename: A
authors.initials: A
authors.lastname: Grzelak
authors.forename: R
authors.initials: R
authors.lastname: Grześkowiak
authors.forename: P
authors.initials: P
authors.lastname: Weglenski
mesh_terms: D020121:5' Untranslated Regions; D000595:Amino Acid Sequence; D001119:Arginase / Q000235:genetics*; D001233:Aspergillus nidulans / Q000235:genetics*; D001483:Base Sequence; D003001:Cloning, Molecular; D004271:DNA, Fungal; D005800:Genes, Fungal; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D011401:Promoter Regions, Genetic; D012333:RNA, Messenger / Q000737:chemistry / Q000235:genetics*; D014158:Transcription, Genetic
chemical_list: D020121:5' Untranslated Regions; D004271:DNA, Fungal; D012333:RNA, Messenger; D001119:Arginase