title: Cerium(IV)-Catalyzed Deprotection of Acetals and Ketals under Mildly Basic Conditions.
abstract: Smooth and quantitative deprotection of a wide range of acetals and ketals [Eq. (a); R, R(1)=alkyl, aryl, H] under neutral to mildly basic conditions was achieved with catalytic quantities of cerium ammonium nitrate (CAN). The reaction conditions are compatible with a variety of sensitive functional groups, and aldehydes can be liberated from acetals without being oxidized to the corresponding carboxylic acids.
authors.affiliation: Université catholique de Louvain, Département de Chimie, Laboratoire de Chimie Organique Batiment Lavoisier, Place Louis Pasteur 1, B-1348 Louvain-la-Neuve (Belgium).
authors.initials: IE
authors.lastname: Markó
authors.initials: A
authors.lastname: Ates
authors.initials: A
authors.lastname: Gautier
authors.initials: B
authors.lastname: Leroy
authors.initials: JM
authors.lastname: Plancher
authors.initials: Y
authors.lastname: Quesnel
authors.initials: JC
authors.lastname: Vanherck