title: The effect of intra-articular irrigation injection therapy on osteoarthrosis of the temporomandibular joint.
abstract: OBJECTIVE
  To investigate the effect of intra-articular irrigation-injection therapy in treating osteoarthrosis of the temporomandibular joint.
  
  
  METHODS
  Thirty-seven patients (the test group) received intra-articular irrigation injection; 26 patients (the control group) received intra-articular injection of steroid. The synovial fluid, aspirated from five subjects of the test group before and after the therapy, was assayed to determine the tumor necrosis factor.
  
  
  RESULTS
  Clinical evaluations were performed 3 months after the therapy. Thirteen subjects in the test group fell into the "excellent" category, 19 into the "good" category, and five into the "no effect" category; in the control group, eight subjects fell into the "excellent" category; nine into the "good" category, and nine into the "no effect" category. The category difference in total effectiveness between the test group and the control group is statistically significant (X2 = 3.9340 P < 0.05). TNF in synovial fluid also showed statistically significant differences before and after treatment (T = 2.8825, P < 0.05).
  
  
  CONCLUSIONS
  Intra-articular irrigation injection is an effective therapy method for treating osteoarthrosis and is superior to intra-articular injection of steroid.
authors.affiliation: Department of Stomatology, First Teaching Hospital, Zhejiang Medical University (ZMU), P. R. China.
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Gu
authors.forename: H L
authors.initials: HL
authors.lastname: Wu
authors.forename: Q L
authors.initials: QL
authors.lastname: Wu
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Cao
authors.forename: Y X
authors.initials: YX
authors.lastname: Zhang
mesh_terms: D000328:Adult; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D007270:Injections, Intra-Articular; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D019152:Paracentesis; D011239:Prednisolone / Q000008:administration & dosage; D013582:Synovial Fluid / Q000737:chemistry; D013705:Temporomandibular Joint Disorders / Q000188:drug therapy*; D007507:Therapeutic Irrigation / Q000379:methods; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis
chemical_list: D014409:Tumor Necrosis Factor-alpha; D008012:Lidocaine; D011239:Prednisolone