title: Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine.
abstract: Cancer-screening tests for internal organs are severely constrained by low specificity or sensitivity, cost, and morbidity. We report a non-invasive immunofluorometric assay for detection of urothelial cancers based on ectopic expression of the DNA replication protein Mcm5.
authors.forename: K
authors.initials: K
authors.lastname: Stoeber
authors.forename: I
authors.initials: I
authors.lastname: Halsall
authors.forename: A
authors.initials: A
authors.lastname: Freeman
authors.forename: R
authors.initials: R
authors.lastname: Swinn
authors.forename: A
authors.initials: A
authors.lastname: Doble
authors.forename: L
authors.initials: L
authors.lastname: Morris
authors.forename: N
authors.initials: N
authors.lastname: Coleman
authors.forename: N
authors.initials: N
authors.lastname: Bullock
authors.forename: R A
authors.initials: RA
authors.lastname: Laskey
authors.forename: C N
authors.initials: CN
authors.lastname: Hales
authors.forename: G H
authors.initials: GH
authors.lastname: Williams
mesh_terms: D014408:Biomarkers, Tumor; D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D018797:Cell Cycle Proteins / Q000652:urine*; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D012680:Sensitivity and Specificity; D001749:Urinary Bladder Neoplasms / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor; D018797:Cell Cycle Proteins; C489423:MCM5 protein, human