title: Is there a negative correlation between explicit memory and hippocampal volume?
abstract: The aim of this research was to study the relationship between explicit memory and hippocampal volume. Seventy healthy adults were administered one implicit memory test and one explicit memory (EM) test and underwent magnetic resonance imaging. The major finding was a negative correlation between the EM test and the right hippocampus/brain volume ratio (t = -0.25, P = 0.03) and the left hippocampus/brain volume ratio (t = -0.27, P = 0.02). This finding is not consistent with pathologic findings, which tend to show a relationship between decrease in memory performance and hippocampal atrophy. This discrepancy is discussed.
authors.affiliation: Department of Biological Anthropology and Genetic Epidemiology, INSERM U155, University Paris VII, 2 Place Jussieu, Paris 05, 75251, France.
authors.forename: M
authors.initials: M
authors.lastname: Chantôme
authors.forename: P
authors.initials: P
authors.lastname: Perruchet
authors.forename: D
authors.initials: D
authors.lastname: Hasboun
authors.forename: D
authors.initials: D
authors.lastname: Dormont
authors.forename: M
authors.initials: M
authors.lastname: Sahel
authors.forename: N
authors.initials: N
authors.lastname: Sourour
authors.forename: A
authors.initials: A
authors.lastname: Zouaoui
authors.forename: C
authors.initials: C
authors.lastname: Marsault
authors.forename: M
authors.initials: M
authors.lastname: Duyme
mesh_terms: D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D005260:Female; D006624:Hippocampus / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D012016:Reference Values; D012153:Retention, Psychology / Q000502:physiology; D014706:Verbal Learning / Q000502:physiology