title: [Anaphylactic reactions to systemic corticosteroids. Review of the literature concerning 3 cases].
abstract: Despite their antiinflammatory and antiallergic properties, corticosteroids can nevertheless cause adverse allergic reactions. This is currently accepted for local corticosteroids and there have also been about a hundred reports of variable pertinence concerning hypersensitivity reactions to systemic corticosteroids. Based on three cases of immediate hypersensitivity reactions after taking methylprednisolone, we propose a critical review of the literature, focusing particularly on methylprednisolone-induced reactions. The means of investigation currently available in drug-induced hypersensitivity reactions are also discussed.
authors.affiliation: Hôpital de la Croix-Rousse, Lyon.
authors.forename: P
authors.initials: P
authors.lastname: Beynel
authors.forename: J C
authors.initials: JC
authors.lastname: Guérin
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced*; D000893:Anti-Inflammatory Agents / Q000009:adverse effects* / Q000276:immunology; D004342:Drug Hypersensitivity / Q000503:physiopathology* / Q000517:prevention & control; D006801:Humans; D008775:Methylprednisolone / Q000009:adverse effects* / Q000276:immunology
chemical_list: D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone