title: Surgical treatment of penile carcinoma: our experience from 1976 to 1997.
abstract: OBJECTIVE
  The purpose of this work is to evaluate our experience with the surgical treatment of penile squamous carcinoma, analyzing the therapeutic results in terms of local recurrence rates, survival and mortality rates.
  
  
  METHODS
  From 1976 to 1997, 47 patients were treated at our institution for carcinoma of penis. Treatment of primary tumor was conservative in 8 patients (17%). Partial penectomy was performed in 30 patients (63.8%); total penectomy in 5 (10.7%) and emasculation in 4 (8.5%). Pathological stage was pTis in 2 cases (4.2%), pT1 in 20 (42.6%), pT2 in 21 (44. 7%) and pT3 in 4 (8.5%). The tumor was clinically overstaged in 13 patients (27.7%) and understaged in 4 (8.5%). Bilateral inguinal lymphadenectomy was performed only in 4 patients clinically N+ (pN2) and in 3 clinically N0 (pN0).
  
  
  RESULTS
  Local recurrence rate was 43% in the patients with pT1 stage tumor treated conservatively. No local recurrence was observed after penectomy. 19 patients (40.4%) are alive and disease-free; 17 patients (36.2%) died of the tumor and 11 patients (23.4%) died of other causes but disease-free. Mean follow-up is 69.43 months. The overall 5-year survival rate was 34%.
  
  
  CONCLUSIONS
  Partial penectomy gives better results than conservative treatment in the local management of the T1 stage tumor. Survival and mortality rates are related to both pathological and histological stages. The high mortality rate observed in the pT2 stage tumors in our experience might be related to the fact that in this stage an inguinal lymphadenectomy was not performed as a rule.
authors.affiliation: Department of Urology, University of Verona, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Ficarra
authors.forename: A
authors.initials: A
authors.lastname: D'Amico
authors.forename: S
authors.initials: S
authors.lastname: Cavalleri
authors.forename: G
authors.initials: G
authors.lastname: Zanon
authors.forename: A
authors.initials: A
authors.lastname: Mofferdin
authors.forename: D
authors.initials: D
authors.lastname: Schiavone
authors.forename: G
authors.initials: G
authors.lastname: Malossini
authors.forename: G
authors.initials: G
authors.lastname: Mobilio
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D010412:Penile Neoplasms / Q000401:mortality / Q000601:surgery*; D010413:Penis / Q000601:surgery; D015996:Survival Rate; D013997:Time Factors