[Elimination of CD28+ T cell in patients with chronic active hepatitis].
OBJECTIVE
To study the role of toxicyte T cell in active hepatitis.


METHODS
We examined CD28+ T cell in patients with chronic active/remission hepatitis by flow cytometry.


RESULTS
It shows that CD28+, CD8+CD28+ T cell in patients with chronic active hepatitis decreased significantly, compared with normal control or patients with liver cirrhosis and heptoma.


CONCLUSIONS
It implies that B7-CD28 costimulation pathway contribute to the tissue injury in hepatitis.
Deng
A
A
Clinical Immunology Center, Changzheng Hospital, Shanghai.
Zhong
R
R
Chen
S
S
D018106:CD28 Antigens / Q000032:analysis*; D006521:Hepatitis, Chronic / Q000276:immunology*; D006801:Humans; D013601:T-Lymphocytes / Q000276:immunology*
D018106:CD28 Antigens