title: MR angiography with superparamagnetic iron oxide: feasibility study.
abstract: Magnetic resonance (MR) angiography with blood-pool superparamagnetic iron oxide (SPIO) particles was evaluated in the whole-body vascular system. In 12 adult patients, three-dimensional fast imaging with steady-state precession was performed in successive steps from the lungs to the calves before and after a standard dose for liver imaging (15 mumol of iron per kilogram of body weight) of AMI-25. On SPIO-enhanced MR angiograms, visualization of the pulmonary arterial, whole-body, and lower extremity venous systems was graded as good or sufficient in all patients, and femoral vein thrombosis was clearly demonstrated in one patient.
authors.affiliation: Department of Radiology, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Germany. s.schmitz@medizin.fu-berlin.de
authors.forename: S A
authors.initials: SA
authors.lastname: Schmitz
authors.forename: T
authors.initials: T
authors.lastname: Albrecht
authors.forename: K J
authors.initials: KJ
authors.lastname: Wolf
mesh_terms: D000328:Adult; D000368:Aged; D005240:Feasibility Studies; D005260:Female; D005290:Ferric Compounds; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008280:Magnetics; D008297:Male; D008875:Middle Aged
chemical_list: D005290:Ferric Compounds; C000499:ferric oxide