[A case of congenital plasminogen abnormality with recurrent cerebrovascular ischemic attacks].
We reported a 10-year-old boy with congenital plasminogen abnormality resulting in recurrent cerebrovascular ischemic attacks. He suddenly developed dystonia of the left upper limb at 9 years of age. MRI demonstrated small infarcts in the right thalamus and caudate nucleus. He then had a transient ischemic attack at 10 years. He complained of headache, vertigo, diplopia, and unsteady gait. DNA analysis revealed that he was heterozygotic for abnormal plasminogen. Thus, congenital plasminogen abnormality was suspected to be a cause of recurrent cerebrovascular ischemic attacks in this case.
Kato
T
T
Department of Pediatrics, Anjo Kosei Hospital, Aichi.
Hayakawa
F
F
Okumura
A
A
Kuno
K
K
Watanabe
K
K
D002544:Cerebral Infarction / Q000209:etiology; D002648:Child; D006579:Heterozygote; D006801:Humans; D002546:Ischemic Attack, Transient / Q000209:etiology*; D008297:Male; D009154:Mutation; D010958:Plasminogen / Q000235:genetics*; D012008:Recurrence
D010958:Plasminogen