Endothelium-dependent flow-mediated vasodilation in the postprandial state in type 2 diabetes mellitus.
This study examined the effects of fat- plus sucrose-rich meals on endothelium-dependent flow-mediated vasodilation in diabetic patients. Flow-mediated vasodilation in the postprandial state decreased significantly, and the decrease correlated inversely with the magnitude of postprandial hyperglycemia, suggesting that endothelial function in diabetic patients becomes impaired postprandially.
Shige
H
H
First Department of Internal Medicine, National Defense Medical College, Saitama, Japan.
Ishikawa
T
T
Suzukawa
M
M
Ito
T
T
Nakajima
K
K
Higashi
K
K
Ayaori
M
M
Tabata
S
S
Ohsuzu
F
F
Nakamura
H
H
D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000503:physiopathology*; D004730:Endothelium, Vascular / Q000503:physiopathology*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D019518:Postprandial Period / Q000502:physiology*; D014664:Vasodilation / Q000502:physiology*
D006442:Glycated Hemoglobin