Declining immunoglobulin A production in prostates of men with AIDS.
We studied immunoglobulin A production (IgA) in prostates of men with AIDS. Prostate sections from AIDS patients and human immunodeficiency virus-negative men were stained for IgA with immunoperoxidase. Prostate sections from nondiseased men were positive for IgA, while prostate sections from AIDS patients were essentially negative for IgA. Diminishing secretory IgA production may represent a characteristic of AIDS.
Carson
H J
HJ
Department of Pathology, Mercy Medical Center, Cedar Rapids, Iowa 52403, USA. hjcmd@earthlink.net
Lueck
N E
NE
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology* / Q000635:transmission; D000293:Adolescent; D000328:Adult; D006801:Humans; D007124:Immunoenzyme Techniques; D007070:Immunoglobulin A / Q000032:analysis / Q000096:biosynthesis*; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000276:immunology* / Q000821:virology*; D012749:Sexually Transmitted Diseases / Q000276:immunology / Q000821:virology
D007070:Immunoglobulin A