[Factor IX inhibitor in hemophilia B presented with anaphylactoid symptoms: report of 3 cases].
Three patient with hemophilia B who developed anti-factor IX antibodies were reported. All 3 had allergic and/or anaphylactoid symptoms when the antibodies were found. The antibodies were noted between 4 and 17 days after exposure to factor IX. It was suggested that the anaphylactoid symptoms were closely related to the occurrence of anti-factor IX antibodies.
Taketani
T
T
Division of Hematology/Oncology, Saitama Children Medical Center.
Hanada
R
R
Kawaguchi
H
H
Ida
K
K
Yamamoto
K
K
D000707:Anaphylaxis / Q000188:drug therapy / Q000209:etiology*; D000906:Antibodies / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D005164:Factor IX / Q000276:immunology*; D002836:Hemophilia B / Q000150:complications*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007223:Infant; D008297:Male
D000906:Antibodies; D007166:Immunosuppressive Agents; D005164:Factor IX