title: Blockade of neuropathic pain by antisense targeting of tetrodotoxin-resistant sodium channels in sensory neurons.
authors.affiliation: Department of Pharmacology, University of Arizona, Tucson 85724, USA.
authors.forename: J
authors.initials: J
authors.lastname: Lai
authors.forename: J C
authors.initials: JC
authors.lastname: Hunter
authors.forename: M H
authors.initials: MH
authors.lastname: Ossipov
authors.forename: F
authors.initials: F
authors.lastname: Porreca
mesh_terms: D000818:Animals; D002908:Chronic Disease; D004351:Drug Resistance; D015640:Ion Channel Gating; D008026:Ligation; D008161:Lumbosacral Region; D062556:NAV1.7 Voltage-Gated Sodium Channel; D062559:NAV1.8 Voltage-Gated Sodium Channel; D009475:Neurons, Afferent / Q000187:drug effects*; D009479:Neuropeptides / Q000187:drug effects / Q000235:genetics; D020319:Oligodeoxyribonucleotides, Antisense / Q000627:therapeutic use*; D010146:Pain / Q000188:drug therapy*; D010148:Intractable Pain / Q000188:drug therapy; D059348:Peripheral Nerve Injuries; D010525:Peripheral Nerves / Q000187:drug effects; D051381:Rats; D015222:Sodium Channels / Q000187:drug effects* / Q000235:genetics; D013127:Spinal Nerves / Q000601:surgery; D013779:Tetrodotoxin / Q000494:pharmacology
chemical_list: D062556:NAV1.7 Voltage-Gated Sodium Channel; D062559:NAV1.8 Voltage-Gated Sodium Channel; D009479:Neuropeptides; D020319:Oligodeoxyribonucleotides, Antisense; C568319:Scn10a protein, rat; C503480:Scn9a protein, rat; D015222:Sodium Channels; D013779:Tetrodotoxin