title: Desmoplastic small round cell tumour of the pleura: a case report with further cytogenetic and ultrastructural evidence of 'mesothelioblastemic' origin.
abstract: A typical case of desmoplastic small round cell tumour of the pleura in a 25-year-old man is described. In addition to the typical histological and immunohistological findings, the EWS-WT1 fusion product was also observed. Ultrastructurally, some tumour cells displayed intracytoplasmic neolumina, with short microvilli characteristic of submesothelial cells. These findings support the theory of a splanchnopleuric intraembryonic mesodermal, 'mesothelioblastemic' origin, both morphologically and cytogenetically.
authors.affiliation: Department of Pathology, St. John's Hospital, Budapest, Hungary.
authors.forename: Z
authors.initials: Z
authors.lastname: Sápi
authors.forename: Z
authors.initials: Z
authors.lastname: Szentirmay
authors.forename: Z
authors.initials: Z
authors.lastname: Orosz
mesh_terms: D000328:Adult; D018288:Carcinoma, Small Cell / Q000648:ultrastructure*; D018222:Desmoid Tumors / Q000473:pathology; D006801:Humans; D008297:Male; D010997:Pleural Neoplasms / Q000648:ultrastructure*