title: Sultamo-steroid analogues, Part VII: Synthesis of epi-androsterone derivatives with potential activity.
abstract: The reaction of epi-androsterone with cyanoacetyl hydrazine (2) gave the hydrazone derivative 3. The reactivity of 3 towards chemical reagents was studied to give pyridine, thiazole and thiophene derivatives.
authors.affiliation: Hormone Department, National Research Centre, Dokki, Cairo, Egypt. rmmohareb@hotmail.com
authors.forename: S H
authors.initials: SH
authors.lastname: Doss
authors.forename: N A
authors.initials: NA
authors.lastname: Louca
authors.forename: G A
authors.initials: GA
authors.lastname: Elmegeed
authors.forename: R M
authors.initials: RM
authors.lastname: Mohareb
mesh_terms: D000738:Androsterone / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D011725:Pyridines / Q000138:chemical synthesis* / Q000494:pharmacology; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D013876:Thiophenes / Q000138:chemical synthesis* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D011725:Pyridines; D013844:Thiazoles; D013876:Thiophenes; D000738:Androsterone