[Treatment of lipid disorders for coronary heart disease prevention according to International Atherosclerosis Society recommendations].
In this paper the results of recently published primary and secondary prevention trials of coronary heart disease using statins are presented. Statins are effective in patients with high and mean serum cholesterol levels, in elderly patients in men and in women. The IAS Expert Group recommendations concerning hyperlipidemia treatment in coronary heart disease prevention are presented. Lowering LDL-cholesterol, the most atherogenic lipoprotein fraction is a goal of the treatment and LDL-cholesterol level is recommended for monitoring of efficacy of the treatment. Hypertriglyceridemia (1.7-4.5 mmol/l) is a coronary heart disease risk factor, however the role of triglyceride lowering in coronary heart disease prevention remains to be established by clinical trials. Assessment and treatment of all coronary risk factors is essential for prevention.
Idzior-Waluś
B
B
Katedry i Kliniki Chorób Metabolicznych Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.
D000368:Aged; D003327:Coronary Disease / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D017408:Guidelines as Topic; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D006949:Hyperlipidemias / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012955:Societies, Medical / Q000592:standards
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors