title: [Development of visual acuity in the early phase after photorefractive keratectomy in myopia].
abstract: BACKGROUND
  Photorefractive keratectomy (PRK) using the excimer laser is an accepted surgical technique for correction of myopic refraction errors in case of spectacle or contact lens incompatibility. The purpose of this study was to assess the development of uncorrected (UVA) and best-corrected visual acuity (CVA) in the early course following PRK.
  
  
  METHODS
  48 eyes of 29 patients that underwent myopic photorefractive keratectomy using 193 nm excimer laser (MEL 60, Aesculap-Meditec) were included in this study. The mean preoperative spherical equivalent was -5.3 +/- 2.4 diopters (D) (range -1.75 to -9.5 D). Pre-, intra- and postoperative treatment was standardized. The median time interval to complete epithelial closure was 2 days. According to their spherical equivalent, patients were divided in two groups: group 1 with myopia < or = 6 D (n = 28), group 2 with myopia more than 6 D (n = 20). Examination of UVA and CVA were performed preoperatively and on days 3, 7 as well as 1 month, 3 and 6 months postoperatively.
  
  
  RESULTS
  On day 3 after surgery UVA was 0.43 +/- 0.21 for group 1 with myopia < or = 6 D, and 0.36 +/- 0.14 for group 2 with myopia more than 6 D. The UVA was stable after 3 months (0.92 +/- 0.29 and 0.66 +/- 0.20, respectively), the CVA was stable after 1 month (1.04 +/- 0.18 and 0.86 +/- 0.19, respectively). After surgery, the UVA increased by +0.73 +/- 0.25, whereas the CVA increased by +0.05 +/- 0.10 for the whole group. The difference comparing pre- and postoperative UVA was significantly higher in group 1 (0.81 +/- 0.22) than in group 2 (0.60 +/- 0.26) (p = 0.002). However, postoperative CVA values were not significantly different from preoperative values in both groups after 6 months (p = 0.3).
  
  
  CONCLUSIONS
  Useful uncorrected visual acuity is normally achieved at day 3 after PRK in eyes with mild to moderate myopia. With higher degrees of myopia the uncorrected visual acuity does increase slower towards a lower level. One of the reasons for this phenomenon might be a significant regression of the refractive effects during the first half year after surgery.
authors.affiliation: Augenklinik mit Poliklinik, Universität Erlangen-Nürnberg. nhung.nguyen@augen.med.uni-erlangen.de
authors.forename: N X
authors.initials: NX
authors.lastname: Nguyen
authors.forename: A
authors.initials: A
authors.lastname: Langenbucher
authors.forename: A
authors.initials: A
authors.lastname: Walter
authors.forename: M
authors.initials: M
authors.lastname: Küchle
authors.forename: B
authors.initials: B
authors.lastname: Seitz
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D054018:Lasers, Excimer; D008297:Male; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D018903:Photorefractive Keratectomy; D011183:Postoperative Complications / Q000503:physiopathology*; D013997:Time Factors; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology*