corticofugal regulation of excitatory and inhibitory frequency tuning curves of bat inferior collicular neurons.
Corticofugal regulation of excitatory and inhibitory frequency tuning curves (FTCs) of neurons in the central nucleus of bat inferior colliculus (ICc) was studied by electrical stimulation of the primary auditory cortex (AC stimulation) under free field stimulation conditions using a two-tone inhibition paradigm. AC stimulation narrowed the excitatory FTCs and asymmetrically expanded the lateral inhibitory FTCs of corticofugally inhibited ICc neurons. The opposite results were observed for excitatory and inhibitory FTCs of corticofugally facilitated ICc neurons. These data support previous reports that corticofugal systems work together with widespread lateral inhibition to regulate subcortical frequency processing.
Jen
P H
PH
Division of Biological Sciences, University of Missouri, Columbia 65211, USA. jenp@missouri.edu
Zhang
J P
JP
D000161:Acoustic Stimulation; D000818:Animals; D001303:Auditory Cortex / Q000502:physiology*; D001306:Auditory Pathways / Q000502:physiology; D001307:Auditory Perception / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology*; D002685:Chiroptera; D004558:Electric Stimulation; D007245:Inferior Colliculi / Q000502:physiology*; D009474:Neurons / Q000502:physiology*