Perfusion-based event-related functional MRI.
Perfusion-based event-related functional MRI was performed by measuring flow-sensitive alternating inversion recovery (FAIR) signal changes during repeated single-trial, short visual stimulation (250 msec). In the visual cortex activation area, the blood flow increases immediately after the stimulus, reaches the maximum 4 sec later with a perfusion-sensitized signal change of 16. 1 +/- 2.6 %, and then decreases to baseline approximately 11 sec after the stimuli. As it is a more direct reflection of the hemodynamic response, perfusion-based event-related functional MRI techniques may be more useful for human cognitive function studies, compared with blood oxygenation level-dependent (BOLD)-based event-related functional MRI techniques. Magn Reson Med 42:1011-1013, 1999.
Liu
H L
HL
Research Imaging Center, University of Texas Health Science Center at San Antonio, 78284-6240, USA.
Gao
J H
JH
D002560:Cerebrovascular Circulation / Q000502:physiology; D017352:Echo-Planar Imaging / Q000379:methods; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010775:Photic Stimulation; D014793:Visual Cortex / Q000033:anatomy & histology* / Q000098:blood supply