title: Effect of homocysteine on the production of nitric oxide in endothelial cells.
abstract: 1. Homocysteine decreased the release of nitric oxide in cultured human umbilical vein endothelial cells. 2. Homocysteine did not affect constitutive and inducible nitric oxide synthase activity.
authors.affiliation: Department of Pharmacology, Faculty of Medicine, University of Hong Kong, SAR China.
authors.forename: K
authors.initials: K
authors.lastname: Chow
authors.forename: F
authors.initials: F
authors.lastname: Cheung
authors.forename: T T
authors.initials: TT
authors.lastname: Lao
authors.forename: K
authors.initials: K
authors.lastname: O
mesh_terms: D002461:Cell Line, Transformed; D004730:Endothelium, Vascular / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism*; D006710:Homocysteine / Q000494:pharmacology*; D006801:Humans; D009569:Nitric Oxide / Q000096:biosynthesis*; D019001:Nitric Oxide Synthase / Q000378:metabolism; D052247:Nitric Oxide Synthase Type II; D052250:Nitric Oxide Synthase Type III
chemical_list: D006710:Homocysteine; D009569:Nitric Oxide; C496319:NOS2 protein, human; C496314:NOS3 protein, human; D019001:Nitric Oxide Synthase; D052247:Nitric Oxide Synthase Type II; D052250:Nitric Oxide Synthase Type III