title: Single breath exhaled nitric oxide in lung transplant patients: a preliminary clinical study.
abstract: Exhaled nitric oxide is considered as a marker of airway inflammation. We report here our preliminary experience with single-breath exhaled nitric oxide measured in lung transplant patients with and without bronchiolitis obliterans syndrome and in cardiac transplant patients. Peak and end-expiratory nitric oxide concentrations did not differ between groups, but single-breath exhaled nitric oxide recordings were strikingly different in patients suffering from bronchiolitis obliterans syndrome, with a slower decrease from peak to end-expiratory nitric oxide concentration. Further studies are required in order to determine whether theses abnormalities reflect the inflammatory process of bronchiolitis obliterans syndrome.
authors.affiliation: Service de Chirurgie Thoracique et Cardiovasculaire, Hôpital Broussais, 96 rue Didot, F-75 014 Paris, France. rachidzegdi@post.club-internet.fr
authors.forename: R
authors.initials: R
authors.lastname: Zegdi
authors.forename: R
authors.initials: R
authors.lastname: Guillmain
authors.forename: C
authors.initials: C
authors.lastname: Amrein
authors.forename: P
authors.initials: P
authors.lastname: Chevalier
authors.forename: P
authors.initials: P
authors.lastname: Lajos
authors.forename: J P
authors.initials: JP
authors.lastname: Couëtil
authors.forename: A
authors.initials: A
authors.lastname: Carpentier
authors.forename: J N
authors.initials: JN
authors.lastname: Fabiani
mesh_terms: D000328:Adult; D001944:Breath Tests; D001989:Bronchiolitis Obliterans / Q000175:diagnosis*; D005260:Female; D006801:Humans; D016040:Lung Transplantation / Q000009:adverse effects*; D009569:Nitric Oxide / Q000032:analysis*
chemical_list: D009569:Nitric Oxide