title: Evaluation of 18F-FDG positron emission tomography in gastric and oesophageal carcinoma.
abstract: The aim of this study was to evaluate 18F-fluoro-deoxyglucose (FDG) positron emission tomography (PET) in gastric and oesophageal carcinoma. 16 patients with biopsy proven oesophageal or gastric carcinoma had PET scans. Four patients had advanced disease and received palliative treatment. The remaining 12 patients were randomized to immediate surgery or neoadjuvant chemotherapy. Three patients had repeat PET scans following chemotherapy. PET detected the primary tumour in all cases including stage T1 lesions. Involved locoregional nodes (N1, N2) were not identified separately from the primary tumour. Semiquantitative analysis was performed in the form of tumour to liver activity ratios (TLR). In general, the TLR values were higher in the higher T stages, although there was only one case each of T1 and T2 lesions. PET scanning using 18F-FDG is a sensitive method for detecting primary oesophageal and gastric cancers but is limited in locoregional staging.
authors.affiliation: Department of Radiology, Aberdeen Royal Infirmary, Foresterhill, UK.
authors.forename: D
authors.initials: D
authors.lastname: McAteer
authors.forename: F
authors.initials: F
authors.lastname: Wallis
authors.forename: G
authors.initials: G
authors.lastname: Couper
authors.forename: M
authors.initials: M
authors.lastname: Norton
authors.forename: A
authors.initials: A
authors.lastname: Welch
authors.forename: D
authors.initials: D
authors.lastname: Bruce
authors.forename: K
authors.initials: K
authors.lastname: Park
authors.forename: M
authors.initials: M
authors.lastname: Nicolson
authors.forename: F J
authors.initials: FJ
authors.lastname: Gilbert
authors.forename: P
authors.initials: P
authors.lastname: Sharp
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D019275:Radiopharmaceuticals; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18