Renal cell carcinoma with massive osseous metaplasia and bone marrow elements.
Focal calcifications are frequently seen in renal masses and may be present in renal cell carcinomas. Metaplastic bone formation, on the other hand, is a rare event. We report a unique case of a large calcified renal cell carcinoma with massive osseous metaplasia and bone marrow elements. The clinical and pathologic differential diagnosis for this tumor is discussed along with a review of the literature on this unusual phenomenon.
Cribbs
R K
RK
Departments of Pathology, Surgery, and Medicine, The Ohio State University Medical Center, Columbus, OH 43210, USA.
Ishaq
M
M
Arnold
M
M
O'Brien
J
J
Lamb
J
J
Frankel
W L
WL
D014408:Biomarkers, Tumor / Q000032:analysis; D001853:Bone Marrow / Q000473:pathology*; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology; D002292:Carcinoma, Renal Cell / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007680:Kidney Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology*; D008679:Metaplasia; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D014057:Tomography, X-Ray Computed
D014408:Biomarkers, Tumor