title: Limitations of clinical diagnosis in acute stroke.
abstract: Trials in acute stroke have recruited on the basis of clinical diagnosis. Using MRI we have shown that clinical diagnosis is more limited than previously appreciated, thus trials may have been underpowered or confounded.
authors.forename: S J
authors.initials: SJ
authors.lastname: Allder
authors.forename: A R
authors.initials: AR
authors.lastname: Moody
authors.forename: A L
authors.initials: AL
authors.lastname: Martel
authors.forename: P S
authors.initials: PS
authors.lastname: Morgan
authors.forename: G S
authors.initials: GS
authors.lastname: Delay
authors.forename: J R
authors.initials: JR
authors.lastname: Gladman
authors.forename: P
authors.initials: P
authors.lastname: Fentem
authors.forename: G G
authors.initials: GG
authors.lastname: Lennox
mesh_terms: D002986:Clinical Trials as Topic / Q000706:statistics & numerical data*; D015986:Confounding Factors, Epidemiologic; D003951:Diagnostic Errors / Q000706:statistics & numerical data*; D006801:Humans; D020521:Stroke / Q000175:diagnosis* / Q000188:drug therapy