title: [Neurologic complications of chemotherapy].
abstract: BACKGROUND
  Neurotoxicity can be induced by the synergistic or additive effects of cytotoxic treatments, and nervous system exposure is related to routes and doses.
  
  
  BACKGROUND
  The improvements in treating systemic malignancy have been accompanied by reports of neurologic toxicity, which has an important impact on the quality of life and may even limit the use of the treatment.
  It demands out a continuous clinical evaluation to detect their appearance. When neurological complications are diagnosed later, they are rarely reversible. Neuroprotective agents are still being evaluated.
authors.affiliation: Service de neurologie, CHU, Nice, France.
authors.forename: C
authors.initials: C
authors.lastname: Lebrun
authors.forename: M
authors.initials: M
authors.lastname: Frenay
authors.forename: M
authors.initials: M
authors.lastname: Lanteri-Minet
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy; D009422:Nervous System Diseases / Q000139:chemically induced*; D011788:Quality of Life
chemical_list: D000970:Antineoplastic Agents