title: [A recurrent case of esophageal cancer in which metastatic skin tumor disappeared after local injection of activated lymphocytes with tumor-pulsed dendritic cells].
abstract: We examined the effect of activated lymphocytes stimulated with tumor-pulsed dendritic cells (DC-K), and found that such stimulation enhanced the cytotoxity of the activated lymphocytes. Furthermore, in applying DC-K to a recurrent case of esophageal cancer, the skin tumors disappeared after local injection of DC-K. The only adverse effect of this treatment was pyrexia. Although no general effect was observed, the local effect was satisfactory. This suggests that DC-K might be useful for local treatment or postoperative adjuvant therapy.
authors.affiliation: Second Dept. of Surgery, Gifu University School of Medicine.
authors.forename: N
authors.initials: N
authors.lastname: Nagao
authors.forename: M
authors.initials: M
authors.lastname: Katoh
authors.forename: I
authors.initials: I
authors.lastname: Kumazawa
authors.forename: H
authors.initials: H
authors.lastname: Tomita
authors.forename: Y
authors.initials: Y
authors.lastname: Sugiyama
authors.forename: K
authors.initials: K
authors.lastname: Kunieda
authors.forename: K
authors.initials: K
authors.lastname: Miya
authors.forename: S
authors.initials: S
authors.lastname: Saji
mesh_terms: D000368:Aged; D003713:Dendritic Cells / Q000637:transplantation*; D004938:Esophageal Neoplasms / Q000473:pathology*; D006801:Humans; D016219:Immunotherapy, Adoptive; D015979:Killer Cells, Lymphokine-Activated / Q000637:transplantation; D008297:Male; D012878:Skin Neoplasms / Q000556:secondary* / Q000628:therapy*