Bone architecture and image synthesis.
3-D bone architecture can now be measured by micro-computer tomography or micro-magnetic resonance imaging. The principles of the micro-computer technique is reviewed and new architectural parameters can be computed. In addition, the method allows the contruction of polymer models by stereolithography, a method that can be used to perform repetitive mechanical studies on the same bone sample. These non destructive methods are interesting in the pre-clinical studies on bone diseases and in the investigation of animal trials on new pharmacological compounds active on bone.
Gross
G J
GJ
Procter & Gamble Pharmaceuticals, Health Care Research Center, Mason, Ohio 45040, USA.
Dufresne
T E
TE
Smith
T
T
Cockman
M D
MD
Chmielewski
P A
PA
Combs
K S
KS
Borah
B
B
D000818:Animals; D001842:Bone and Bones / Q000033:anatomy & histology*; D005289:Ferrets / Q000033:anatomy & histology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D051381:Rats / Q000033:anatomy & histology*