The vasculitides.
Vascular inflammation stands at the center of innumerable physiological and pathological processes. Dissecting the mechanisms of successful vascular injury and repair, investigators provide information for scientists and clinicians. The neurologist benefits from studies across several disciplines. Details of the cellular functions in the infiltrates of temporal arteries impart a basis for rational therapy. The interactions of herpes virus with vessels wall remind us of the affinity of numerous infectious agents for the vasculature. Several animal models are enabling us to explore the genetic links in autoimmunity. Although clinical studies may not yet provide us with answers for accurate diagnosis and treatment of many of our patients, data from this year will keep our interest high.
Moore
P M
PM
Department of Neurology, University of Pittsburgh, Pennsylvania 15213, USA.
D001323:Autoantibodies / Q000276:immunology; D001921:Brain / Q000098:blood supply*; D006801:Humans; D014657:Vasculitis / Q000145:classification* / Q000276:immunology
D001323:Autoantibodies