Epidemiology of human hookworm infections among adult villagers in Hejiang and Santai Counties, Sichuan Province, China.
Hookworm infection as well as other intestinal nematodiases are endemic to Sichuan Province in China. In order to research the prevalence and intensity of these infections we visited two villages in Hejiang County (southern Sichuan Province) and Santai County (northwestern Sichuan Province) between July and October of 1997. Fecal examinations were performed on adult villagers over the age of 15 years (currently children under this age are dewormed annually with anthelmintic drugs). Among 310 residents of Lugao Village (Hejiang County), 87, 63 and 60% were infected with hookworm, Ascaris or Trichuris, respectively. The prevalence of hookworm determined to rise linearly with age (r = 0.97). High intensity infections with hookworm still occur in this region as 22% of the residents have over 3000 eggs per gram (PEG) of feces as determined by quantitative egg counts. The majority of these individuals harbored mixed infection with Necator americanus and Ancylostoma duodenale, although the former predominated when adult hookworms were collected from 30 village residents treated with pyrantel pamoate. In contrast, among the 334 Xinjian villagers examined (Santai County) the majority harbored predominantly light hookworm infections--66.1% of the residents has less than 400 EPG by quantitative fecal examination and only 3.7% exhibited greater than 3000 EPG. Again, N. americanus was the predominant hookworm seen after worm expulsion. We have round that despite economic development which is occurring in some parts of China, significant hookworm infections and clinical hookworm anemia still exist in areas of Sichuan Province. In Hejiang County we found that the intensity of hookworm infection has actually risen within the last 10 years. Hookworm is a medical problem among the elderly in Sichuan.
Changhua
L
L
Sichuan Institute of Parasitic Diseases, PR China.
Xiaorong
Z
Z
Dongchuan
Q
Q
Shuhua
X
X
Hotez
P J
PJ
Defu
Z
Z
Hulian
Z
Z
Mingden
L
L
Hainan
R
R
Bing
Z
Z
Haichou
X
X
Hawdon
J
J
Zheng
F
F
D000293:Adolescent; D000328:Adult; D000722:Ancylostoma / Q000302:isolation & purification*; D000724:Ancylostomiasis / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology; D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use; D001196:Ascariasis / Q000453:epidemiology / Q000469:parasitology; D002681:China / Q000453:epidemiology; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D008297:Male; D017221:Necator americanus / Q000302:isolation & purification*; D009332:Necatoriasis / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology; D010270:Parasite Egg Count; D015995:Prevalence; D011715:Pyrantel / Q000627:therapeutic use; D012423:Rural Health; D014257:Trichuriasis / Q000453:epidemiology / Q000469:parasitology
D000969:Antinematodal Agents; D011715:Pyrantel