[Population-based study of antibodies to certain potential infectious triggers of spondylarthropathies: a study of Ugro-Finnish population of Russia].
A study was made of antibodies to some enterobacteria--potential triggers of spondyloarthropathies in population of mordva characterized by higher frequency of HLA-B27. 141 and 148 plasm samples were taken from erzya and moksha subpopulations, respectively. Enzyme immunoassay has detected specific antibodies IgA, IgM, IgG to Salmonella, Yersinia, Campylobacter and Klebsiella. Specific immune response in the mordva population appeared to depend on gender, age and nationality but not HLA-B27. In the study population the role of Klebsiella infection in development of ankylosing spondylarthritis was not confirmed though the number of the patients was not sufficient to reject this suggestion.
Guseva
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Iksila I
Erdes
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Toĭvanen
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Benevolenskaia
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D000914:Antibodies, Viral / Q000276:immunology*; D002391:Catchment Area, Health; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D012426:Russia; D013167:Spondylitis, Ankylosing / Q000208:ethnology / Q000209:etiology* / Q000276:immunology*
D000914:Antibodies, Viral