[Chlamydiae--still new surprises].
A review on participation of chlamydiae in the origin of the HIV-infection, carcinoma and atherosclerosis. The antibodies against the newly discovered pgp3 protein of C. trachomatis were found in 83-87% of the seropositive HIV patients. The participation of C. trachomatis in the etiology of cervical and ovarian carcinoma has been discussed in a number of articles. Simultaneous examinations along different lines allow the hypothesis, that C. trachomatis acts as a cofactor in the development of ovarian and cervical carcinoma. Chronic infection by C. pneumoniae appears to be one of the risk factors of pulmonary carcinoma. Many papers dealing with the relation of chlamydiae and atherosclerosis have been published. The relation between the chronic C. pneumoniae-infection and atherosclerosis has been assessed serologically and by direct demonstration of chlamydiae in atheromatous plaques.
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Výzkumný ústav veterinárního lékarství, Brno.
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis*; D001161:Arteriosclerosis / Q000175:diagnosis / Q000382:microbiology*; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis; D016993:Chlamydophila pneumoniae; D005260:Female; D005833:Genital Neoplasms, Female / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans