title: [Conservative therapy of fistulas of the anorectal area in Crohn disease].
abstract: The conservative treatment of ano-rectal fistulae in Crohn's disease is selected according to the clinical activity and chronicity of the underlying disease. While in the acute phase metronidazole is indicated in addition to the standard therapy, an immuno-suppressive treatment with azathrioprine is recommended for the chronic-active course. The long latency of the therapeutic response can be bridged by an intravenous therapy with either cyclosporine ot with high-dose azathropine. The treatment is initiated only after consultation with the surgeon. For the prophylaxis of a post-surgical recurrence, only salicylates are established. Further inter-discipline therapy intended to induce a pre-surgical remission or to maintain a post-surgical remission.
authors.affiliation: Klinik für Gastroenterologie, Hepatologie und Infektiologie, Medizinische Fakultät, Otto-von-Guericke-Universität Magdeburg.
authors.forename: U
authors.initials: U
authors.lastname: Peitz
authors.forename: U
authors.initials: U
authors.lastname: Brucks
authors.forename: P
authors.initials: P
authors.lastname: Malfertheiner
mesh_terms: D003424:Crohn Disease / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008795:Metronidazole / Q000008:administration & dosage*; D011183:Postoperative Complications / Q000188:drug therapy*; D011379:Prognosis; D012003:Rectal Fistula / Q000188:drug therapy*; D012008:Recurrence; D012459:Salicylates / Q000008:administration & dosage*
chemical_list: D007166:Immunosuppressive Agents; D012459:Salicylates; D008795:Metronidazole