title: Site-directed alteration of genomic DNA by small-fragment homologous replacement.
authors.affiliation: Cardiovascular Research Institute, University of California, San Francisco, USA.
authors.forename: K K
authors.initials: KK
authors.lastname: Goncz
authors.forename: D C
authors.initials: DC
authors.lastname: Gruenert
mesh_terms: D015139:Blotting, Southern; D002460:Cell Line; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics; D004247:DNA / Q000032:analysis; D018390:Gene Targeting / Q000379:methods*; D015316:Genetic Therapy; D015894:Genome, Human; D006801:Humans; D008081:Liposomes / Q000737:chemistry; D016297:Mutagenesis, Site-Directed; D009838:Oligodeoxyribonucleotides; D012313:RNA / Q000032:analysis; D011995:Recombination, Genetic; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014162:Transfection
chemical_list: C505032:CFTR protein, human; D008081:Liposomes; D009838:Oligodeoxyribonucleotides; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D012313:RNA; D004247:DNA