Fatal phenytoin hypersensitivity syndrome.
The phenytoin (hydantoin) hypersensitivity syndrome is rare but potentially fatal. Often, as in this case, it presents with non-specific symptoms and signs, requiring a high degree of clinical suspicion for diagnosis.
Mahadeva
U
U
Northwick Park and St Mark's Hospitals NHS Trust, Department of Cellular Pathology, Watford Road, Harrow HA1 3UJ, UK.
Al-Mrayat
M
M
Steer
K
K
Leen
E
E
D000368:Aged; D000369:Aged, 80 and over; D000927:Anticonvulsants / Q000009:adverse effects; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D010672:Phenytoin / Q000009:adverse effects*
D000927:Anticonvulsants; D010672:Phenytoin