Lattice-like collagen fiber meshwork in the iris stroma of the cat: a possible mechanism to generate the tension directed towards the iris root which is required for pupillary dilatation in the sympathectomized eye.
NaOH digestion technique for collagen fiber dissection and scanning electron microscopy demonstrated a lattice-like meshwork in the anterior surface of the iris stroma of the cat. The mesh threads were made of collagen fibril bundles. In the constricted pupil, the meshes were square to rhomboid with the diagonals in the direction of the radius or circumference of the iris. In the dilated pupil, however, the meshes were strongly flattened rhomboid or ellipse with a longer diagnoal or axis in the circumferential direction. At the mesh corners facing the pupillary margin or the iris root, the collagen fibril bundles were strongly bent in the iris of the constricted pupil, while they were almost straight or slightly wavy in the iris of the dilated pupil. Accumulation of elasticity tension generated by this small distortion of the iris-mesh threads in the constricted pupil was considered to generate a tension directed towards the iris root, which is required for pupillary dilatation in the sympathectomized eye. On the posterior surface of the iris stroma, numerous thin pleats tightly woven with collagen fibrils traversed straightway through the radial length of the ciliary zone of the iris in both constricted and dilated pupils. The structural changes of these pleats in miosis and mydriasis were very small compared with the meshwork of the anterior aspect of the iris. Therefore, they were considered to work mainly as an iris skeleton.
Sakuraba
M
M
Department of Anatomy, Hirosaki University School of Medicine, Japan.
Yun
S
S
Ichinohe
N
N
Yonekura
H
H
Shoumura
K
K
D000818:Animals; D002415:Cats; D003094:Collagen / Q000378:metabolism / Q000648:ultrastructure*; D004548:Elasticity; D005123:Eye / Q000294:innervation*; D005260:Female; D066298:In Vitro Techniques; D007429:Intraocular Pressure / Q000502:physiology*; D007498:Iris / Q000378:metabolism / Q000502:physiology / Q000648:ultrastructure*; D008297:Male; D008855:Microscopy, Electron, Scanning; D012025:Reflex, Pupillary / Q000502:physiology*; D013562:Sympathectomy; D013564:Sympathetic Nervous System / Q000502:physiology*
D003094:Collagen