title: [Computer analysis of regulatory signals in complete bacterial genomes. Translation initiation of ribosomal protein operons].
abstract: Signals of translation initiation of operons of Haemophilus influenzae ribosomal proteins were predicted. This process is regulated by the formation of secondary RNA structures to which one of the proteins encoded in a particular operon binds. In some cases, these structures imitate the region of protein binding to rRNA. Predictions are made by comparing with homologous operons of Escherichia coli and analogous regions of rRNA and by estimating the energy of secondary structure formation. It is shown that this regulatory mechanism occurs: in operons L11, S10, S15, spc, and alpha of H.influenzae and, probably, in operon S15 of Helicobacter pylori, Bacillus subtilis, and Mycoplasma genitalium.
authors.affiliation: Institute of Problems of Data Transmission, Russian Academy of Sciences, Moscow, Russia.
authors.forename: A
authors.initials: A
authors.lastname: Vitreshchak
authors.forename: A K
authors.initials: AK
authors.lastname: Bansal
authors.forename: I I
authors.initials: II
authors.lastname: Titov
authors.forename: M S
authors.initials: MS
authors.lastname: Gel'fand
mesh_terms: D001483:Base Sequence; D016680:Genome, Bacterial; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009876:Operon; D014176:Protein Biosynthesis; D012329:RNA, Bacterial / Q000737:chemistry / Q000235:genetics; D012269:Ribosomal Proteins / Q000235:genetics*
chemical_list: D012329:RNA, Bacterial; D012269:Ribosomal Proteins