SAPHO syndrome: report of three cases and review of the literature.
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) is an acronym that describes a seronegative syndrome of bone and joint lesions, frequently localized to the anterior chest wall, associated with variable dermatologic manifestations. Dermatologists should be aware of this entity, as early diagnosis can prevent unnecessary surgery and avoid prolonged ineffective antibiotic therapy. We report three new cases and review the literature.
Gmyrek
R
R
Department of Dermatology, New York-Presbyterian Hospital, Columbia Presbyterian Center, New York, USA.
Grossman
M E
ME
Rudin
D
D
Scher
R
R
D020083:Acquired Hyperostosis Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001707:Biopsy, Needle; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013256:Steroids / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed; D014212:Tretinoin / Q000008:administration & dosage
D000900:Anti-Bacterial Agents; D013256:Steroids; D014212:Tretinoin