[Myasthenia gravis. Opportunistic cytomegalovirus infection after long-term azathioprine therapy].
Opportunistic infections after long-term treatment with azathioprine (AZA) have not been noted in patients with myasthenia gravis (MG). We report on a 56-year-old woman with generalized MG who presented with cytomegalovirus infection after being treated with AZA for 17 years. The indication for immunosuppressive treatment in MG should be regularly reconfirmed, particularly since at least 50% of patients can discontinue AZA after two to four years without risk of exacerbation.
Eisensehr
I
I
Neurologische Klinik, Klinikum Grosshadern, Ludwig-Maximilians-Universität, München.
Büttner
U
U
Witt
T N
TN
von Appen
K
K
Spuler
S
S
D001379:Azathioprine / Q000008:administration & dosage / Q000009:adverse effects*; D003586:Cytomegalovirus Infections / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D008134:Long-Term Care; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000188:drug therapy*; D009894:Opportunistic Infections / Q000139:chemically induced* / Q000175:diagnosis
D007166:Immunosuppressive Agents; D001379:Azathioprine