Cold lesion of a vertebral angioma with Tc-99m-labeled monoclonal antibodies against granulocytes.
Antigranulocyte immunoscintigraphy is indicated for diagnostic imaging to determine the location and extent of infection. We present a case of a focal cold lesion in a vertebra of a patient thought to have a septic focal lesion. Whole-body scanning and dorsal spine SPECT revealed no focal increased uptake. CT and MR studies revealed the presence of a vertebral angioma. Conditions associated with a defect of uptake in immunoscintigraphy are discussed.
Giacomuzzi
F
F
Division of Nuclear Medicine and Radiology, S.M.M. Hospital, Udine, Italy.
Di Gregorio
F
F
Capobianco
D
D
De Cristofaro
M
M
Moretti
C A
CA
Guerra
U P
UP
D000911:Antibodies, Monoclonal; D005188:False Negative Reactions; D005260:Female; D006391:Hemangioma / Q000175:diagnosis / Q000000981:diagnostic imaging*; D006801:Humans; D007962:Leukocytes; D008875:Middle Aged; D016719:Radioimmunodetection; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon
D000911:Antibodies, Monoclonal; C104213:BW 250 183