[The effect of current methods of induction anesthesia on the systolic and diastolic functions of the left and right heart in patients with ischemic heart disease].
Perioperative echocardiography and right ventricular volumic monitoring were used for more essential evaluation of different hypnotics in cardiosurgical patients. Our comparative study has shown that all the examined hypnotics induced no changes in systolic function of the left ventricle. Midazolam and propofol exerted minor depressive influence only on diastolic left ventricular function without significant fall of cardiac output. Etomidate moderately worsened diastolic and systolic right ventricular function with cardiac output decrease. The combined use of diazepam and ketamine provided excellent hemodynamic stability without negative effects on systolic and diastolic heart function.
Trekova
N A
NA
Iavorovskiĭ
A G
AG
Flerov
E V
EV
Iumatov
A E
AE
Kovalevskaia
O A
OA
Asmangulian
E T
ET
Grishin
V V
VV
D000368:Aged; D003971:Diastole / Q000187:drug effects; D005260:Female; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods; D017202:Myocardial Ischemia / Q000503:physiopathology* / Q000601:surgery; D009204:Myocardial Revascularization; D011229:Preanesthetic Medication / Q000379:methods*; D013599:Systole / Q000187:drug effects
D006993:Hypnotics and Sedatives