title: Abnormality in saccadic eye movement in dementia.
abstract: In a small (n = 15) clinically heterogeneous group of patients with dementia of the Alzheimer-type or vascular dementia, abnormally high frequency of saccadic intrusions during fixation was significantly correlated to the Mini-Mental-State-Examination (MMSE) scores. In addition, the latency of saccades and hypometric saccades also correlated significantly to MMSE-scores. The results point to the possible use of saccadic eye movement as a physiological marker of cognitive performance.
authors.affiliation: Department of Psychiatry, Humboldt-Universität zu Berlin (Charité), Schumannstr. 20-21, 10117 Berlin, Germany.
authors.forename: H J
authors.initials: HJ
authors.lastname: Schewe
authors.forename: R
authors.initials: R
authors.lastname: Uebelhack
authors.forename: K
authors.initials: K
authors.lastname: Vohs
mesh_terms: D000368:Aged; D003704:Dementia / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010507:Periodicity; D011569:Psychiatric Status Rating Scales; D012438:Saccades / Q000502:physiology*; D012720:Severity of Illness Index