title: Azoospermia in two Labrador retrievers.
abstract: Azoospermia is described in two sibling Labrador Retriever dogs. Clinical investigations following failure to sire pups after normal matings revealed testicular hypoplasia and degeneration. Sperm were absent on repeated ejaculate examination in both dogs. Histopathological examination of testicular needle aspirate biopsy and whole testicle of the first dog displayed an absence of spermatids and spermatocytes. Seminiferous tubules containing Sertoli cells with or without primary spermatogonia were present in the second dog. Peritubular lymphocyte accumulation was also present in both dogs. The dogs had been conceived using frozen-thawed semen.
authors.affiliation: Institute of Reproduction and Development, Monash Medical Centre, Clayton, Victoria.
authors.forename: S S
authors.initials: SS
authors.lastname: Metcalfe
authors.forename: I M
authors.initials: IM
authors.lastname: Gunn
authors.forename: K A
authors.initials: KA
authors.lastname: Champness
mesh_terms: D000469:Alkaline Phosphatase / Q000032:analysis; D000818:Animals; D001707:Biopsy, Needle / Q000662:veterinary; D002369:Castration / Q000662:veterinary; D004283:Dog Diseases / Q000473:pathology / Q000503:physiopathology*; D004285:Dogs; D004542:Ejaculation; D004822:Epididymis / Q000473:pathology / Q000503:physiopathology; D006651:Histocytochemistry; D008297:Male; D009845:Oligospermia / Q000473:pathology / Q000503:physiopathology / Q000662:veterinary*; D012661:Semen / Q000166:cytology / Q000201:enzymology; D012671:Seminiferous Tubules / Q000473:pathology; D012708:Sertoli Cells / Q000473:pathology; D013737:Testis / Q000473:pathology* / Q000503:physiopathology
chemical_list: D000469:Alkaline Phosphatase