[Churg-Strauss syndrome in a 15-year old boy].
A 15 year-old boy was admitted in our hospital with the clinical signs of cardiopulmonary deterioration. His history showed bronchial asthma since 3 years. Furthermore he revealed signs of polyneuropathy, exanthema and a transitory pulmonary infiltration. Elevation of eosinophilic granulocytes and IgE confirmed the diagnosis of a Churg-Strauss syndrome. A rapid improvement of the symptoms was achieved by high-dose steroids and symptomatic therapy. The impaired systolic and diastolic myocardial function improved, but a cardiomyopathy with a shortening fraction below 25% persisted. The Churg-Strauss syndrome is a rare disease in childhood and is classified as a systemic granulomatosis of the vessels. The marked perimyocarditis with consecutive restrictive cardiomyopathy is a rare manifestation in childhood and adolescence. The prognosis of this disease is mainly influenced by the cardiac involvement.
Reinhard
H
H
Universitätsklinik für Kinder- und Jugendmedizin Homburg, Saar.
Lindinger
A
A
Geib-König
R
R
Graf
N
N
D000293:Adolescent; D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000209:etiology*; D008297:Male; D009205:Myocarditis / Q000209:etiology*; D010493:Pericarditis / Q000209:etiology*; D013256:Steroids / Q000627:therapeutic use; D018487:Ventricular Dysfunction, Left / Q000209:etiology*
D013256:Steroids