title: [Evaluation of two methods for endometrial sampling during diagnostic hysteroscopy].
abstract: OBJECTIVE
  To compare two endometrial sampling devices, pipelle and vacurette, performed during hysteroscopy, based on the quality of material obtained and pain during the sampling.
  
  
  METHODS
  During the period from 01.03.96 to 01.12.97, 200 patients were consecutively randomized in a single blind prospective study. Efficacity was evaluated on the quality of material obtained and pain was graded on a scale of 0 to 5.
  
  
  RESULTS
  On the average the Vacurette was more painful (1.6 vs 1.1, p = 0.01). Vacurette biopsy was more effective than pipelle biopsy (64% vs 48%, p = 0.05). There was a significative difference of efficacity in the post-menopausal group (34% vs 13%, p = 0.05), but not in the pre-menopausal group (76% vs 64%, p > 0.05). When hysteroscopy diagnosed endometrial atrophy, there was no significative difference of efficacity (29% vs 23%, p > 0.05), whereas vacurette was significatively more effective when there was an other hysteroscopy diagnosis (78% vs 62%, p = 0.05). Both procedures were less effective in post-menopausal women (p = 0.001), and in case of endometrial atrophy (p = 0.001).
  
  
  CONCLUSIONS
  Both procedures were acceptable during ambulatory hysteroscopy. In our study, vacurette was more painful than pipelle. Vacurette was more effective but insufficient tissue for histologic evaluation was important in both procedures. This might be explained by the population included and the histologic method used.
authors.affiliation: Service de Gynécologie-Obstétrique, Hôpital de la Conception, Marseille.
authors.forename: A
authors.initials: A
authors.lastname: Agostini
authors.forename: L
authors.initials: L
authors.lastname: Cravello
authors.forename: M C
authors.initials: MC
authors.lastname: Rojat-Habib
authors.forename: J
authors.initials: J
authors.lastname: Amabile-Boulat
authors.forename: V
authors.initials: V
authors.lastname: Roger
authors.forename: F
authors.initials: F
authors.lastname: Bretelle
authors.forename: B
authors.initials: B
authors.lastname: Blanc
mesh_terms: D001706:Biopsy; D004717:Endometrium / Q000473:pathology*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D015203:Reproducibility of Results; D016037:Single-Blind Method; D014618:Vacuum