title: Creatine kinase MB isoenzyme of noncardiac origin in elderly patients.
abstract: Increased activity of creatine kinase MB (CKMB) isoenzyme is regarded as highly diagnostic for acute myocardial infarction. We report two cases of elderly patients with increased levels of CKMB but no evidence of cardiac injury. We conclude that numerous factors influence CKMB activity and that the suitability of this test for the diagnosis of cardiac muscle damage in the elderly should be viewed with caution.
authors.affiliation: Geriatric Department, Meir General Hospital, Kfar Saba, Israel.
authors.forename: P
authors.initials: P
authors.lastname: Alterman
authors.forename: C
authors.initials: C
authors.lastname: Vigder
authors.forename: J
authors.initials: J
authors.lastname: Feldman
authors.forename: D
authors.initials: D
authors.lastname: Spiegel
authors.forename: A
authors.initials: A
authors.lastname: Yaretzky
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003402:Creatine Kinase / Q000097:blood / Q000378:metabolism*; D003937:Diagnosis, Differential; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis; D006801:Humans; D007527:Isoenzymes; D008173:Lung Diseases, Obstructive / Q000201:enzymology; D008297:Male; D009206:Myocardium / Q000201:enzymology*; D011014:Pneumonia / Q000201:enzymology
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase