title: Myofibroblastoma of the neck in a heifer.
abstract: A 1.5-year-old Holstein heifer had a subcutaneous tumor mass (20 cm diameter) on the ventral portion of the neck, and the tumor was diagnosed as a locally invasive myofibroblastoma. It consisted of moderately cellular fibrous tissue, and the interlobular septum of the thymus was invaded by tumor cells. The neoplastic cells were positive for alpha smooth muscle actin and vimentin, but not for desmin. Electron microscopy disclosed the presence of moderately developed rough endoplasmic reticulum and microfilaments with focal densities.
authors.affiliation: Ishikari Livestock Hygiene Service Center, Sapporo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Hikita
authors.forename: Y
authors.initials: Y
authors.lastname: Yabuki
authors.forename: Y
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: T
authors.initials: T
authors.lastname: Shibahara
authors.forename: K
authors.initials: K
authors.lastname: Kadota
mesh_terms: D000199:Actins / Q000032:analysis / Q000276:immunology; D000818:Animals; D000911:Antibodies, Monoclonal; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D003893:Desmin / Q000032:analysis / Q000276:immunology; D018870:Endoplasmic Reticulum, Rough / Q000473:pathology; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D007150:Immunohistochemistry; D008854:Microscopy, Electron / Q000662:veterinary; D009379:Neoplasms, Muscle Tissue / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis / Q000276:immunology; D013950:Thymus Gland / Q000473:pathology; D014746:Vimentin / Q000032:analysis / Q000276:immunology
chemical_list: D000199:Actins; D000911:Antibodies, Monoclonal; D003893:Desmin; D018809:Proliferating Cell Nuclear Antigen; D014746:Vimentin