title: Ovarian masses in children.
abstract: We evaluated the outcome of children with ovarian mass operated on at our Center over an 8-year period. Thirty-four girls aged 1 day to 17 years were included in the study. Mean duration of follow-up was 39.5 months. Eighteen had a nonneoplastic mass and 16 a neoplastic mass, eight of which were malignant. Patients with a malignant tumor underwent adnexectomy of the affected side and appendectomy, without removal of the uterus or the other ovary and without partial omentectomy; only the one girl with bilateral malignant disease had bilateral adnexectomy. Five of the eight patients with malignant disease received chemotherapy. All patients are alive with no evidence of disease. Pediatric ovarian masses are rare but have a relatively high rate of malignancy. They differ from adult malignant tumors in many aspects. Conservative surgery should be applied to preserve fertility and combined, if necessary, with aggressive chemotherapy. A good prognosis may be expected in most cases, even with progressive disease.
authors.affiliation: Department of Pediatric Surgery and Oncology, Schneider Children's Medical Center of Israel, Petah Tiqva, Israel.
authors.forename: E
authors.initials: E
authors.lastname: Freud
authors.forename: D
authors.initials: D
authors.lastname: Golinsky
authors.forename: R M
authors.initials: RM
authors.lastname: Steinberg
authors.forename: A
authors.initials: A
authors.lastname: Blumenfeld
authors.forename: I
authors.initials: I
authors.lastname: Yaniv
authors.forename: M
authors.initials: M
authors.lastname: Zer
mesh_terms: D000290:Adnexa Uteri / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D013511:Minor Surgical Procedures; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery*; D010052:Ovariectomy; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents