title: Mytilus edulis histone gene clusters containing only H1 genes.
abstract: We isolated five different phage clones containing histone gene clusters with up to five H1 genes per phage clone from a Mytilus edulis genomic library. Among these H1 genes, nine gene types coding for five different H1 proteins have been identified. All H1 histone genes were located on repetitive restriction fragments with only slightly different sizes. The H1 coding regions show highly related sequences, suggesting that the multitude of H1 genes has evolved by gene duplication events. Core histone genes could not be found on these five Mytilus edulis genome fragments.
authors.affiliation: Institute of Biochemistry and Molecular Cell Biology, Department of Molecular Biology, Georg-August-University Göttingen, Humboldtallee 23, D-37073 Göttingen, Germany. bdraben@gwdg.de
authors.forename: B
authors.initials: B
authors.lastname: Drabent
authors.forename: J S
authors.initials: JS
authors.lastname: Kim
authors.forename: W
authors.initials: W
authors.lastname: Albig
authors.forename: E
authors.initials: E
authors.lastname: Prats
authors.forename: L
authors.initials: L
authors.lastname: Cornudella
authors.forename: D
authors.initials: D
authors.lastname: Doenecke
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D010582:Bacteriophage lambda / Q000235:genetics; D001483:Base Sequence; D049872:Bivalvia / Q000235:genetics*; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D018900:Dinucleotide Repeats; D019143:Evolution, Molecular; D020440:Gene Duplication; D015698:Genomic Library; D006657:Histones / Q000235:genetics*; D008969:Molecular Sequence Data; D005810:Multigene Family; D015183:Restriction Mapping; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid
chemical_list: D006657:Histones; D004247:DNA