title: Retinal thickness analysis in subjects with different refractive conditions.
abstract: OBJECTIVE
  The aim of the present study is to evaluate a measure of retinal thinning at the posterior pole in eyes with increasing axial myopia.
  
  
  METHODS
  129 eyes of 79 healthy persons with different refractive conditions were examined using a commercially available prototype of retinal thickness analyzer.
  
  
  RESULTS
  Increasing myopia has been found to be accompanied by bulbus elongation, and calculation of the values obtained with the instrument revealed a significant decrease in retinal thickness at the posterior pole in eyes with increasing axial myopia, i.e. 4.8 microm/spherical equivalent in the foveolar region and 6.6 microm/spherical equivalent in the other areas of the posterior pole.
  
  
  CONCLUSIONS
  Our data show retinal thinning at the posterior pole in myopic eyes based for the very first time on in vivo measurements. Furthermore, our findings might influence measurement data for other purposes, if the degree of myopia is not taken into account.
authors.affiliation: Department of Ophthalmology and Optometry, University of Innsbruck, Austria. bernhard.kremser@uibk.ac.at
authors.forename: B
authors.initials: B
authors.lastname: Kremser
authors.forename: J
authors.initials: J
authors.lastname: Troger
authors.forename: M
authors.initials: M
authors.lastname: Baltaci
authors.forename: M
authors.initials: M
authors.lastname: Kralinger
authors.forename: G F
authors.initials: GF
authors.lastname: Kieselbach
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000473:pathology*; D011379:Prognosis; D012029:Refraction, Ocular; D012160:Retina / Q000473:pathology*; D014792:Visual Acuity