Large granular lymphocytic leukemia in a mixed breed dog.
A mixed breed dog was diagnosed with large granular lymphocytic leukemia. Immunophenotypic analysis indicated the lymphocytes were CD3+, CD8+ T cells expressing the alpha beta T cell receptor and a leukointegrin, alpha d. Chemotherapy and splenectomy resulted in an initial reduction in the lymphocyte count.
Lau
K W
KW
Department of Clinical Studies, Ontario Veterinary College, University of Guelph.
Kruth
S A
SA
Thorn
C E
CE
Vernau
W
W
Moore
P
P
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D004283:Dog Diseases / Q000473:pathology* / Q000628:therapy; D004285:Dogs; D005260:Female; D015458:Leukemia, T-Cell / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D013156:Splenectomy / Q000662:veterinary
D000970:Antineoplastic Agents