Pestivirus infection in small ruminants: virological and histopathological findings.
Pestivirus infection was detected in several flocks of sheep and goats located in the south of Italy by means of serological, virological and histopathological investigations. From four animals, two lambs and two kids, showing enteric symptoms which died during the first week of life, four pestivirus strains were isolated and typed as BVDV-like (three isolates) and "tipic" BDV strains (one isolate). The histopathological lesions consisted of areas of hypomyelination in the brain, and a slight depletion of thymic medullary lymphocytes associated with an increase in reticular cells.
Pratelli
A
A
Department of Health and Animal Welfare, Faculty of Veterinary Medicine, Bari, Italy.
Bollo
E
E
Martella
V
V
Guarda
F
F
Chiocco
D
D
Buonavoglia
C
C
D000818:Animals; D018083:Border disease virus / Q000145:classification; D001921:Brain / Q000473:pathology; D018076:DNA, Complementary / Q000235:genetics; D001908:Diarrhea Viruses, Bovine Viral / Q000145:classification; D015511:Goat Diseases / Q000473:pathology / Q000821:virology*; D006041:Goats; D010576:Pestivirus / Q000145:classification* / Q000302:isolation & purification*; D018182:Pestivirus Infections / Q000473:pathology / Q000662:veterinary*; D016133:Polymerase Chain Reaction; D015183:Restriction Mapping; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012756:Sheep; D012757:Sheep Diseases / Q000473:pathology / Q000821:virology*; D013950:Thymus Gland / Q000473:pathology
D018076:DNA, Complementary