title: Isolation of xestosterol esters of brominated acetylenic fatty acids from the marine sponge xestospongia testudinaria
abstract: The CH(2)Cl(2) extract of the marine sponge Xestospongia testudinaria inhibited [(3)H]DPCPX binding to rat-brain adenosine A(1) receptors. Bioassay-guided fractionation led to the isolation of a known brominated acetylenic fatty acid 1 as the active component. Also isolated were two novel sterol esters 2 and 3. All structures were determined on the basis of their spectroscopic data.
authors.affiliation: Queensland Pharmaceutical Research Institute, Griffith University, Brisbane, Australia 4111, and Queensland Museum, P.O. Box 3300, Brisbane, Australia 4101.
authors.initials: NB
authors.lastname: Pham
authors.initials: MS
authors.lastname: Butler
authors.initials: JN
authors.lastname: Hooper
authors.initials: RW
authors.lastname: Moni
authors.initials: RJ
authors.lastname: Quinn