Angiogenesis in endometriosis and angiogenic factors.
Among angiogenic factors, VEGF secreted from activated macrophages under the influence of ovarian steroids, IL-8 expressed in endometrial stromal cells, and basic FGF expressed in endometriotic tissue and PD-ECGF expressed in lining epithelial cells independently of the sex steroidal milieu might contribute to the characteristic advancement of angiogenic lesions in endometriosis in individual manners. Copyrightz1999S.KargerAG,Basel
Fujimoto
J
J
Department of Obstetrics and Gynecology, Gifu University School of Medicine, Gifu, Japan.
Sakaguchi
H
H
Hirose
R
R
Wen
H
H
Tamaya
T
T
D000328:Adult; D016889:Endometrial Neoplasms / Q000209:etiology / Q000473:pathology*; D004715:Endometriosis / Q000150:complications* / Q000209:etiology / Q000473:pathology; D004717:Endometrium / Q000502:physiology; D016228:Endothelial Growth Factors / Q000235:genetics / Q000502:physiology; D005260:Female; D016222:Fibroblast Growth Factor 2 / Q000235:genetics / Q000502:physiology; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D016209:Interleukin-8 / Q000235:genetics / Q000502:physiology; D008222:Lymphokines / Q000235:genetics / Q000502:physiology; D009389:Neovascularization, Pathologic / Q000150:complications* / Q000209:etiology / Q000473:pathology; D013939:Thymidine Phosphorylase / Q000235:genetics / Q000502:physiology; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
D016228:Endothelial Growth Factors; D016209:Interleukin-8; D008222:Lymphokines; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors; D016222:Fibroblast Growth Factor 2; D013939:Thymidine Phosphorylase