Recurrent juvenile-onset laryngotracheal papillomatosis with transformation to squamous cell carcinoma of the lung.
A 47-year-old female patient with recurrent juvenile-onset laryngotracheal papillomatosis for 27 years had multiple bilateral pulmonary lesions, the largest of which was a well-differentiated squamous cell carcinoma. This case is unique because the malignant transformation occurred in a nonirradiated, nonsmoking patient.
Yantsos
V A
VA
Department of Pathology, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, LA, USA.
Farr
G H
GH
McFadden
P M
PM
Emory
W B
WB
D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D010212:Papilloma / Q000473:pathology*; D014134:Tracheal Neoplasms / Q000473:pathology*