Two DR2-associated novel alleles arose from the silent mutation of codon 72: DRB1*16012, DRB5*01012.
Two DRB1*02-associated alleles, DRB1*16012 and DRB5*01012, are described. Both alleles carry the same silent substitution at codon 72.
Lin
Y S
YS
Department of Pediatrics, Georgetown University Medical Center, Washington, DC 20007, USA.
Tang
T F
TF
Ng
J
J
Hartzman
R
R
Hurley
C K
CK
D000483:Alleles; D005091:Exons / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics*; D015802:HLA-DR2 Antigen / Q000235:genetics*; D059811:HLA-DRB1 Chains; D059847:HLA-DRB5 Chains; D006801:Humans; D008969:Molecular Sequence Data; D017354:Point Mutation; D012689:Sequence Homology, Nucleic Acid
D006684:HLA-DR Antigens; D015802:HLA-DR2 Antigen; D059811:HLA-DRB1 Chains; D059847:HLA-DRB5 Chains