Suicidality and substance misuse in first-admitted subjects with psychotic disorder.
OBJECTIVE
The aim of this study was to examine the links between suicidality and substance misuse (abuse or dependence) in subjects with early psychosis.


METHODS
Data were collected on a sample of first-admitted subjects with psychosis (n=64).


RESULTS
More than 1 in 4 patients had a history of parasuicide, and more than 1 in 10 patients were referred to the psychiatric hospital after such an act. Parasuicide was more frequent in subjects with a history of drug misuse (OR=4, 95% CI= 1.1-14.0, P=0.03), and especially of polysubstance use (OR=6.6, 95% CI=1.2-34.7, P=0.03).


CONCLUSIONS
The association between substance misuse and suicidality found in subjects with psychosis is similar to that which exists in the general population. Since early psychosis is a high-risk period for substance misuse, subjects with incipient psychosis may be especially vulnerable to the devastating consequences of drug use with regard to increased risk of suicide.
Verdoux
H
H
Department of Psychiatry, University Victor Segalen, Bordeaux, France.
Liraud
F
F
Gonzales
B
B
Assens
F
F
Abalan
F
F
van Os
J
J
D000293:Adolescent; D000328:Adult; D005260:Female; D006760:Hospitalization; D006778:Hospitals, Psychiatric; D006801:Humans; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000523:psychology* / Q000534:rehabilitation*; D019966:Substance-Related Disorders / Q000523:psychology*; D013405:Suicide / Q000523:psychology*