Perianal Paget's disease.
Perianal Paget's disease is rare. Unlike Paget's disease of the nipple, which is always associated with a subjacent breast adenocarcinoma, perianal Paget's disease is not always associated with a subjacent or visceral malignancy. The treatment recommendation in nearly all reported cases has been surgical excision. Radiation therapy is seldom used as a curative treatment. A case of perianal Paget's disease is described in whom radiation therapy was used with a curative intent after four unsuccessful surgical resections.
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Department of Clinical Oncology, Royal Devon & Exeter Hospital, UK.
D000368:Aged; D001005:Anus Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010145:Paget Disease, Extramammary / Q000473:pathology / Q000532:radiotherapy*