Abnormality in saccadic eye movement in dementia.
In a small (n = 15) clinically heterogeneous group of patients with dementia of the Alzheimer-type or vascular dementia, abnormally high frequency of saccadic intrusions during fixation was significantly correlated to the Mini-Mental-State-Examination (MMSE) scores. In addition, the latency of saccades and hypometric saccades also correlated significantly to MMSE-scores. The results point to the possible use of saccadic eye movement as a physiological marker of cognitive performance.
Schewe
H J
HJ
Department of Psychiatry, Humboldt-Universität zu Berlin (Charité), Schumannstr. 20-21, 10117 Berlin, Germany.
Uebelhack
R
R
Vohs
K
K
D000368:Aged; D003704:Dementia / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010507:Periodicity; D011569:Psychiatric Status Rating Scales; D012438:Saccades / Q000502:physiology*; D012720:Severity of Illness Index