title: Transcatheter renal arterial embolization therapy on a patient with polycystic kidney disease on hemodialysis.
abstract: We report a patient with autosomal dominant polycystic kidney disease (ADPKD) undergoing long-term hemodialysis who underwent transcatheter arterial embolization (TAE) of the renal arteries to shrink enlarged kidneys. In 1983, the patient started hemodialysis because of chronic renal failure secondary to ADPKD. However, renal size continued to increase. In January 1997, he was admitted to our hospital with abdominal distension and anorexia, in addition to progression of anemia. Upper gastroendoscopy showed an esophageal ulcer and severe external compression of the stomach. Renal angiography using the Seldinger technique showed stretched and deformed segmental renal arteries with massive enlargement of the kidneys. TAE with stainless steel coils was performed on both renal arteries. With a rapid and progressive decrease in kidney size, anorexia and anemia were improved, and the gastrointestinal compression was eliminated. In some patients with ADPKD, renal size continues to increase even after the initiation of dialysis. In about 10 years, patients develop gastrointestinal complications, such as dysphagia, ileus, severe constipation, and intestinal perforation. Surgical procedures such as nephrectomy are not satisfactory. This report shows that TAE is a safe and effective therapy for patients with ADPKD with massively enlarged kidneys.
authors.affiliation: Nephrology Center, Toranomon Hospital, Tokyo, Japan. ubara@ma.kcom.ne.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Ubara
authors.forename: H
authors.initials: H
authors.lastname: Katori
authors.forename: T
authors.initials: T
authors.lastname: Tagami
authors.forename: S
authors.initials: S
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Yokota
authors.forename: Y
authors.initials: Y
authors.lastname: Matsushita
authors.forename: F
authors.initials: F
authors.lastname: Takemoto
authors.forename: T
authors.initials: T
authors.lastname: Imai
authors.forename: S
authors.initials: S
authors.lastname: Inoue
authors.forename: K
authors.initials: K
authors.lastname: Kuzuhara
authors.forename: S
authors.initials: S
authors.lastname: Hara
authors.forename: A
authors.initials: A
authors.lastname: Yamada
mesh_terms: D000792:Angiography; D004621:Embolization, Therapeutic; D006801:Humans; D006984:Hypertrophy; D007668:Kidney / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D016891:Polycystic Kidney, Autosomal Dominant / Q000000981:diagnostic imaging / Q000628:therapy*; D012077:Renal Artery / Q000000981:diagnostic imaging; D006435:Renal Dialysis