title: Phospholipin, a novel heterodimeric phospholipase A2 from Pandinus imperator scp6pion venom.
abstract: The primary structure of a phospholipase A2, with unique structural and functional characteristics, was determined. The large subunit has 108 amino acid residues, linked by a disulfide bridge to the small subunit, which contains 17 residues. Its gene was cloned from a cDNA library. The nucleotide sequence showed that the same RNA messenger encodes both subunits, separated only by a pentapeptide, that is processed during maturation.
authors.affiliation: Department of Molecular Recognition and Structural Biology, Biotechnology Institute, National Autonomous University of Mexico, Avenida Universidad, 2001, Apartado Postal 510-3, Cuernavaca, Mexico.
authors.forename: R
authors.initials: R
authors.lastname: Conde
authors.forename: F Z
authors.initials: FZ
authors.lastname: Zamudio
authors.forename: B
authors.initials: B
authors.lastname: Becerril
authors.forename: L D
authors.initials: LD
authors.lastname: Possani
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D019281:Dimerization; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification; D010741:Phospholipases A / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification*; D054467:Phospholipases A2; D012604:Scorpion Venoms / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification*; D017386:Sequence Homology, Amino Acid
chemical_list: D010446:Peptide Fragments; D012604:Scorpion Venoms; C105848:imperatoxin I; C401821:phospholipin; D010741:Phospholipases A; D054467:Phospholipases A2