title: [Relationship between alcoholism and HTR2 MspI polymorphism].
abstract: We investigated the human serotonin receptor, HTR2 genotype among 73 alcoholics. We found that there might not be a significant difference between alcoholics and controls in the frequency of HTR2 C1/C2 gene (MspI polymorphism). This result suggested that the HTR2 C1/C2 gene might not be associated with the risk factor for developing alcohol dependence. Further studies are required to determine whether or not a novel serotonin receptor polymorphism reflects pathogenesis of alcoholism.
authors.affiliation: Department of Physiology, Azabu University, Sagamihara, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Yoshihara
authors.forename: K
authors.initials: K
authors.lastname: Iwahashi
authors.forename: K
authors.initials: K
authors.lastname: Ameno
authors.forename: K
authors.initials: K
authors.lastname: Nakamura
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: M
authors.initials: M
authors.lastname: Enomoto
authors.forename: I
authors.initials: I
authors.lastname: Ijiri
authors.forename: S
authors.initials: S
authors.lastname: Harada
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000235:genetics*; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D011110:Polymorphism, Genetic; D011985:Receptors, Serotonin / Q000235:genetics*; D012307:Risk Factors
chemical_list: D011985:Receptors, Serotonin