title: Palatal myoclonus--a case report.
abstract: Palatal myoclonus is usually due to a brainstem or cerebellar lesion disrupting the dentato-rubro-olivary pathway. Rarely it may be caused by a cortical lesion. The precipitating factor in 70% of all cases is an infarct. We describe an unusual case of a patient with palatal myoclonus who had an old ipsilateral cerebellar infarct and a new contralateral subcortical (corona radiata) infarct. We postulate that the new infarct caused disinhibition of the old cerebellar infarct, resulting in palatal myoclonus. Magnetic resonance imaging (MRI) of the brain did not show any hypertrophy of the inferior olivary nucleus. Her myoclonus proved refractory to clonazepam, valproate and phenytoin.
authors.affiliation: Department of Neurology, National Neuroscience Institute, Singapore.
authors.forename: H C
authors.initials: HC
authors.lastname: Chua
authors.forename: A K
authors.initials: AK
authors.lastname: Tan
authors.forename: N
authors.initials: N
authors.lastname: Venketasubramanian
authors.forename: C B
authors.initials: CB
authors.lastname: Tan
authors.forename: H
authors.initials: H
authors.lastname: Tjia
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D002526:Cerebellar Diseases / Q000150:complications; D002544:Cerebral Infarction / Q000150:complications; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009207:Myoclonus / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D014057:Tomography, X-Ray Computed; D017211:Treatment Failure