title: Novel glutathione analogues containing the dithiol and disulfide form of the Cys-Cys dyad.
abstract: The glutathione analogue gamma-(H-Glu-OH)-Cys-Cys-OH (5), containing the 8-membered disulfide ring -Cys-Cys replacing the native-Cys-Gly fragment, has been synthesized and characterized together with its reduced dithiol form gamma-(H-Glu-OH)-Cys-Cys-OH (6).
authors.affiliation: Dipartimento di Studi Farmaceutici, Università La Sapienza, Roma.
authors.forename: A
authors.initials: A
authors.lastname: Calcagni
authors.forename: G
authors.initials: G
authors.lastname: Lucente
authors.forename: G
authors.initials: G
authors.lastname: Luisi
authors.forename: F
authors.initials: F
authors.lastname: Pinnen
authors.forename: D
authors.initials: D
authors.lastname: Rossi
mesh_terms: D003545:Cysteine / Q000032:analysis*; D004151:Dipeptides / Q000032:analysis; D004220:Disulfides / Q000737:chemistry*; D005978:Glutathione / Q000031:analogs & derivatives* / Q000737:chemistry; D018716:Molecular Mimicry; D014050:Toluene / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D004151:Dipeptides; D004220:Disulfides; D014050:Toluene; D005978:Glutathione; D003545:Cysteine; C004848:dithiol