Serum biochemical values in two inbred strains of mastomys (Praomys coucha).
Serum samples collected from 119 (72 male and 47 female) mastomys (Praomys coucha) of 2 specific-pathogen-free inbred strains (RI4 and RI7) were analyzed for 12 serum biochemical parameters. Sex-related differences (p < 0.01) were noted in alkaline phosphatase and glucose; the both higher in females than in males. Age-related changes (p < 0.01) were observed in total protein, albumin, total cholesterol, and alkaline phosphatase, with higher values for the first three parameters in the older group (200-250 days of age) than in the younger group (90-140 days of age). Four out of 12 parameters showed strain-related differences (p < 0.01), consistent with the large amount of genetic heterogeneity reported in this species. These serum biochemical reference values should provide information for the use of mastomys in laboratory research.
Yamamoto
Y
Y
Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, Japan.
Noguchi
Y
Y
Noguchi
A
A
Nakayama
K
K
Mochida
K
K
Takano
K
K
Koura
M
M
Ogura
A
A
D000818:Animals; D017849:Animals, Inbred Strains / Q000097:blood*; D001774:Blood Chemical Analysis; D005260:Female; D008297:Male; D009115:Muridae / Q000097:blood*; D012016:Reference Values; D013045:Species Specificity; D013047:Specific Pathogen-Free Organisms