title: Not so slowly progressive visual loss.
abstract: A 51-year-old man presented with bilateral progressive visual loss during a 2-month period. Visual acuity was 20/60 in both eyes with bilateral constricted visual fields. Funduscopy revealed bilateral disk pallor and arteriolar attenuation. His vision declined rapidly during the next 2 weeks. Investigations showed a positive cerebrospinal fluid Venereal Disease Research Laboratory test (1:8). A diagnosis of neurosyphilis was made, and treatment was started with high-dose intravenous and intramuscular penicillin.
authors.affiliation: Neuro-Ophthalmology Service, Wills Eye Hospital, Thomas Jefferson University, Phildelphia, Pennsylvania, USA.
authors.forename: H
authors.initials: H
authors.lastname: Danesh-Meyer
authors.forename: K C
authors.initials: KC
authors.lastname: Kubis
authors.forename: R C
authors.initials: RC
authors.lastname: Sergott
mesh_terms: D000907:Antibodies, Bacterial / Q000134:cerebrospinal fluid; D002555:Cerebrospinal Fluid / Q000276:immunology / Q000382:microbiology; D018450:Disease Progression; D004596:Electroretinography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009494:Neurosyphilis / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D010406:Penicillins / Q000627:therapeutic use; D014209:Treponema Immobilization Test; D014210:Treponema pallidum / Q000276:immunology; D014786:Vision Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D014792:Visual Acuity; D014794:Visual Fields
chemical_list: D000907:Antibodies, Bacterial; D010406:Penicillins