title: Novel intronic variants of MICB (MHC class I chain-related gene B).
abstract: We report an eight-nucleotide duplication in intron 4 of the MICB allele 01021, which was found in samples from different ethnic backgrounds and in association with several HLA-B alleles. We suggest that this new MICB allele is evolutionarily older than HLA-B alleles.
authors.affiliation: Anthony Nolan Research Institute, The Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, UK.
authors.forename: G
authors.initials: G
authors.lastname: Fischer
authors.forename: J R
authors.initials: JR
authors.lastname: Argüello
authors.forename: M
authors.initials: M
authors.lastname: Pérez-Rodríguez
authors.forename: S T
authors.initials: ST
authors.lastname: Cox
authors.forename: A
authors.initials: A
authors.lastname: McWhinnie
authors.forename: S G
authors.initials: SG
authors.lastname: Marsh
authors.forename: J A
authors.initials: JA
authors.lastname: Madrigal
mesh_terms: D000483:Alleles; D001402:B-Lymphocytes / Q000737:chemistry; D001483:Base Sequence; D002460:Cell Line; D005006:Ethnicity / Q000235:genetics; D019143:Evolution, Molecular; D005805:Genes, MHC Class I; D015235:HLA-B Antigens / Q000235:genetics; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D007438:Introns / Q000235:genetics*; D015810:Linkage Disequilibrium; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D012689:Sequence Homology, Nucleic Acid
chemical_list: D015235:HLA-B Antigens; D015395:Histocompatibility Antigens Class I; C098080:MICB antigen