Description of the Genetic Analysis Workshop 11 Collaborative Study on the Genetics of Alcoholism.
Problem 1 of Genetic Analysis Workshop 11 consists of data from a family study of the genetics of alcoholism and related traits contributed by the six centers making up the National Institute for Alcohol Abuse and Alcoholism sponsored by the Collaborative Study on the Genetics of Alcoholism (COGA). The family data included 1,214 members of 105 pedigrees ascertained for having three or more individuals affected with alcoholism. Data available to workshop participants included clinical phenotypes, personality measures, smoking behavior, event-related potentials, platelet monamine oxidase B activity, and a genome scan of 296 markers.
Begleiter
H
H
Department of Psychiatry, State University of New York, Health Science Center at Brooklyn, New York 11203, USA.
Reich
T
T
Nurnberger
J
J
Li
T K
TK
Conneally
P M
PM
Edenberg
H
H
Crowe
R
R
Kuperman
S
S
Schuckit
M
M
Bloom
F
F
Hesselbrock
V
V
Porjesz
B
B
Cloninger
C R
CR
Rice
J
J
Goate
A
A
D000437:Alcoholism / Q000235:genetics*; D016022:Case-Control Studies; D002986:Clinical Trials as Topic; D016208:Databases, Factual; D004594:Electrophysiology; D018913:Event-Related Potentials, P300 / Q000235:genetics*; D005820:Genetic Testing; D005838:Genotype; D006801:Humans; D015337:Multicenter Studies as Topic; D010641:Phenotype; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors