title: [High-flow transcranial bypass for prevention of brain ischemia].
abstract: In patients in whom the internal carotid artery has to be occluded because of the presence of an intracranial giant aneurysm or an infiltrating skull base tumour and in patients with brain ischaemia, whose internal carotid artery has been occluded spontaneously on the basis of atherosclerosis, a transcranial bypass can be created. Since the beginning of the seventies 'low-flow bypasses' are made in which a branch of the superficial temporal artery is connected with a cortical branch of the middle cerebral artery. Because of the small calibre of the blood vessels involved the desired effect on the brain circulation is limited. Thanks to the nonocclusive Excimer laser-assisted anastomosing technique, developed by Tulleken et al. in the last fifteen years, it is now possible to create a high-flow bypass in a safe way. A donor vessel, e.g. the V. saphena magna, is connected at one end to the external carotid artery and at the other to the intracranial part of the internal carotid artery beyond the pathological lesion. The mean flow through the bypass was 140 ml/min in about 90 patients. For example, in three patients, a woman aged 45 with rightsided progressive ophthalmoplegia due to a giant aneurysm, a woman aged 31 years with an aneurysm in the right middle ear and a man with a chemodectoma at the base of the skull, a transcranial high-flow bypass was created nonocclusively, after which the internal carotid artery was closed without any problems.
authors.affiliation: Kliniek voor Neurochirurgie, Universitair Medisch Centrum, Utrecht.
authors.forename: C A
authors.initials: CA
authors.lastname: Tulleken
authors.forename: A
authors.initials: A
authors.lastname: van der Zwan
authors.forename: L J
authors.initials: LJ
authors.lastname: Kappelle
mesh_terms: D000328:Adult; D000714:Anastomosis, Surgical / Q000379:methods; D001161:Arteriosclerosis / Q000150:complications; D002545:Brain Ischemia / Q000209:etiology* / Q000517:prevention & control*; D002340:Carotid Artery Diseases / Q000150:complications / Q000601:surgery*; D002342:Carotid Artery, External / Q000601:surgery; D002343:Carotid Artery, Internal / Q000473:pathology / Q000601:surgery*; D002548:Cerebral Revascularization / Q000379:methods*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications; D008297:Male; D008875:Middle Aged; D010236:Paraganglioma, Extra-Adrenal / Q000150:complications; D012501:Saphenous Vein / Q000637:transplantation; D019292:Skull Base Neoplasms / Q000150:complications; D014182:Transplantation, Autologous / Q000379:methods
vernacular_title: Transcraniële bypass met grote doorstroming ter preventie van hersenischemie.