Mutation as an origin of genetic variability in Helicobacter pylori.
The availability of two complete Helicobacter pylori genome sequences and recent studies of its population genetics have provided a detailed picture of genetic diversity in this important human gastric pathogen. It is believed that, in addition to genetic recombination, de novo mutation could have a role in generating the high level of genetic variation in H. pylori.
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Dept of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7. gw4@gpu.srv.ualberta.ca
Humayun
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Taylor
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D004249:DNA Damage; D004260:DNA Repair; D014644:Genetic Variation / Q000235:genetics*; D016680:Genome, Bacterial; D016480:Helicobacter pylori / Q000235:genetics*; D006801:Humans; D009154:Mutation