title: Blood flow in composite arterial grafts and effect of native coronary flow.
abstract: BACKGROUND
  Total arterial coronary revascularization can be achieved by joining arteries together as a composite graft with the proximal left internal mammary artery as the only source of blood inflow. Proof of the capacity of this composite conduit to provide adequate blood flow to the coronary circulation is required.
  
  
  METHODS
  The radial artery was anastomosed to the left internal mammary artery as a Y graft in 17 patients and all coronary arteries grafted. Intraoperative blood flow through the composite grafts was evaluated by the transit-time Doppler technique.
  
  
  RESULTS
  Against no resistance, blood flow in the left internal mammary artery alone was 99 +/- 9 mL/min and rose to 173 +/- 16 mL/min when the radial artery was anastomosed as a Y graft. Composite-graft flow following grafting was 88 +/- 9 mL/min, 49 +/- 6 mL/min when the aortic clamp was removed and native coronary flow restored and 82 +/- 13 mL/min following weaning from cardiopulmonary bypass. The maximal potential flow through the composite graft was 2.3-fold (95% CI 1.6 to 3.2) greater than that after cardiopulmonary bypass.
  
  
  CONCLUSIONS
  Total arterial revascularization, using a composite graft, provided a 2.3-fold reserve of blood flow to the coronary vascular bed through the grafts.
authors.affiliation: Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Parkville, Victoria, Australia. alistair.royse@nwhcn.org.au
authors.forename: A G
authors.initials: AG
authors.lastname: Royse
authors.forename: C F
authors.initials: CF
authors.lastname: Royse
authors.forename: K L
authors.initials: KL
authors.lastname: Groves
authors.forename: B
authors.initials: B
authors.lastname: Bus
authors.forename: G
authors.initials: G
authors.lastname: Yu
mesh_terms: D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D017023:Coronary Angiography; D001026:Coronary Artery Bypass / Q000379:methods*; D003326:Coronary Circulation / Q000502:physiology*; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006801:Humans; D007387:Internal Mammary-Coronary Artery Anastomosis / Q000379:methods*; D017078:Laser-Doppler Flowmetry; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D017534:Radial Artery / Q000637:transplantation*; D014739:Victoria