title: Use of biomarkers in an indoor air study: lack of correlation between aromatic VOCs with respective urinary biomarkers.
abstract: The benzene and toluene levels inside of eight homes with attached garages were measured during July 1998 in Fairbanks, Alaska. A thermal desorption tube method and charcoal tube method were used to collect and analyze samples (thermal desorption tube method %RDS = 1.9 for n = 6; charcoal tube method %RDS = 6.5 for n = 4). Results for both methods were compared and showed indoor benzene levels ranging between 1.2 and 72 ppbv. The charcoal tube method usually gave lower results than the thermal desorption method. Nevertheless, the difference observed in benzene levels from each method was not significant as determined by application of the Wilcoxon t-test to these data. Using the thermal desorption method, the range of toluene found in homes was 0.1-111 ppbv. A correlation between toluene and benzene levels suggested the same point source. The benzene and toluene content of the indoor air and the number of small engines stored in the attached garage was also correlated. There was no correlation found between the urinary biomarker concentrations and the level of benzene or toluene measured inside the homes in the summer.
authors.affiliation: Department of Chemistry and Biochemistry, University of Alaska Fairbanks 99775, USA.
authors.forename: M
authors.initials: M
authors.lastname: Isbell
authors.forename: J
authors.initials: J
authors.lastname: Ricker
authors.forename: M E
authors.initials: ME
authors.lastname: Gordian
authors.forename: L K
authors.initials: LK
authors.lastname: Duffy
mesh_terms: D016902:Air Pollution, Indoor / Q000032:analysis*; D001554:Benzene / Q000032:analysis*; D015415:Biomarkers / Q000652:urine; D002606:Charcoal; D002849:Chromatography, Gas / Q000379:methods; D002851:Chromatography, High Pressure Liquid; D004784:Environmental Monitoring / Q000379:methods*; D006801:Humans; D014050:Toluene / Q000032:analysis* / Q000652:urine; D014835:Volatilization
chemical_list: D015415:Biomarkers; D002606:Charcoal; D014050:Toluene; D001554:Benzene