title: Production of bacteriocin by Bacteriodes fragilis and partial characterization.
abstract: The ability of Bacteroides fragilis strains, isolated from various sources, to produce bacteriocin was evaluated. All strains isolated from intestinal infections were producers in high levels and less susceptible to the others. Strains from other origins were found to produce bacteriocin at a medium level and they were variably susceptible. Some properties of one bacteriocin produced by the Bact. fragilis 079298-3 strain were analysed, providing evidence of its protein nature, with stability over a wide range of pH and retained inhibitory activity after heating. This variability seems to suggest that bacteriocin typing is a good method for this species.
authors.affiliation: Instituto de Microbiologia Professor Paulo de Góes, UFRJ, Rio de Janeiro, Brasil.
authors.forename: K E
authors.initials: KE
authors.lastname: Avelar
authors.forename: L J
authors.initials: LJ
authors.lastname: Pinto
authors.forename: L C
authors.initials: LC
authors.lastname: Antunes
authors.forename: L A
authors.initials: LA
authors.lastname: Lobo
authors.forename: M C
authors.initials: MC
authors.lastname: Bastos
authors.forename: R M
authors.initials: RM
authors.lastname: Domingues
authors.forename: M C
authors.initials: MC
authors.lastname: Ferreira
mesh_terms: D000818:Animals; D001430:Bacteriocins / Q000096:biosynthesis* / Q000494:pharmacology; D001442:Bacteroides Infections / Q000382:microbiology*; D001441:Bacteroides fragilis / Q000187:drug effects / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans
chemical_list: D001430:Bacteriocins