Treatment of recurrent conjunctival papillomatosis with mitomycin C.
OBJECTIVE
To report an effective treatment for recurrent squamous papillomas of the conjunctiva with excision and application of mitomycin C.


METHODS
Case report.


RESULTS
A 5-year-old African-American girl with recurrent squamous papillomas of the right bulbar and palpebral conjunctiva was treated with multiple therapies, including excision, cryotherapy, and conjunctival injection of alpha-interferon; all therapies were followed by recurrence. After treatment with excision followed by intraoperative application of mitomycin C to the involved conjunctiva, the patient had no recurrence in a 30-month period.


CONCLUSIONS
Excision with application of mitomycin C was successful in managing a case of squamous papillomatosis that was resistant to traditional therapy.
Hawkins
A S
AS
Department of Ophthalmology, Rush Medical College of Rush University, Chicago, Illinois 60612, USA.
Yu
J
J
Hamming
N A
NA
Rubenstein
J B
JB
D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D002675:Child, Preschool; D003230:Conjunctival Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D016685:Mitomycin / Q000627:therapeutic use*; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy* / Q000473:pathology; D010212:Papilloma / Q000188:drug therapy* / Q000473:pathology; D019233:Retreatment
D000903:Antibiotics, Antineoplastic; D016685:Mitomycin