title: Lateral ventricle tumors in children: a series of 54 cases.
abstract: A series of 54 patients with lateral ventricle tumors diagnosed and surgically treated from 1988 to 1998 was reviewed. Neoplasms invading ventricles and originating beyond their walls were excluded. There were 35 male and 19 female patients. Their ages ranged from 15 days to 20 years, and two frequency peaks were observed, one at 2 and one at 11 years. The most frequent signs and symptoms were attributed to increased intracranial pressure. The 54 patients included 41 who developed hydrocephalus, but only 15 of these required shunting. The trigonal region and frontal horn were the most common sites of origin. Surgery was planned with due consideration for the localization of the tumor, its presumptive histology, its main feeding vessels, the parenchymal functionality, and the presence or absence of hydrocephalus. The most frequent tumor types were subependymal giant cell astrocytoma, choroid plexus tumors, ependymoma, and astrocytoma. The most common complications were intraventricular hemorrhage, cortical collapse, subdural collection and seizures. To conclude, tumors located within the lateral ventricles are often very voluminous and are predominantly benign, and the treatment of choice is total resection. In the case of malignancy, postsurgical radiotherapy and/or chemotherapy should be given.
authors.affiliation: Department of Neurosurgery, Hospital Nacional de Pediatría "Juan P. Garrahan", Buenos Aires, Argentina. gnzuccaro@ciudad.com.ar
authors.forename: G
authors.initials: G
authors.lastname: Zuccaro
authors.forename: F
authors.initials: F
authors.lastname: Sosa
authors.forename: V
authors.initials: V
authors.lastname: Cuccia
authors.forename: F
authors.initials: F
authors.lastname: Lubieniecky
authors.forename: J
authors.initials: J
authors.lastname: Monges
mesh_terms: D000293:Adolescent; D000328:Adult; D002551:Cerebral Ventricle Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005910:Glioma / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D020547:Lateral Ventricles / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D019635:Neurosurgical Procedures / Q000379:methods*; D012189:Retrospective Studies; D016019:Survival Analysis; D014057:Tomography, X-Ray Computed