[The dynamics of the healing of experimentally reproduced bone defects filled with different polyacrylamide gel-based compounds].
Time course of healing of standard osseous defects by introduction of polyacrylamide gel (PAG)-based materials was studied in rat experiments. PAG did not prevent the formation of soft-tissue and osseous regenerate in bone defects. Addition of hydroxyapatite, bactericidal agent, and lysozyme to PAG-based composition led in some cases to development of chronic inflammation and giant-cell reaction in osseous wound and to inhibition of the reparative processes.
Grigor'ian
A S
AS
Voĭnov
A V
AV
Volozhin
A I
AI
D000180:Acrylic Resins / Q000494:pharmacology / Q000627:therapeutic use*; D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology / Q000627:therapeutic use; D001861:Bone Regeneration / Q000187:drug effects; D018786:Bone Substitutes / Q000494:pharmacology / Q000627:therapeutic use*; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D017886:Durapatite / Q000494:pharmacology / Q000627:therapeutic use; D005269:Femur / Q000187:drug effects / Q000293:injuries*; D005782:Gels; D008297:Male; D009113:Muramidase / Q000494:pharmacology / Q000627:therapeutic use; D051381:Rats; D018030:Silver Compounds / Q000494:pharmacology / Q000627:therapeutic use; D013997:Time Factors; D014945:Wound Healing / Q000187:drug effects*
D000180:Acrylic Resins; D000890:Anti-Infective Agents; D018786:Bone Substitutes; D004338:Drug Combinations; D005782:Gels; C098476:Hydroxyapol; D018030:Silver Compounds; C016680:polyacrylamide gels; D017886:Durapatite; D009113:Muramidase
Dinamika zazhivleniia éksperimental'no vosproizvedennykh kostnykh defektov, zapolnennykh razlichnymi kompozitsiiami na osnove poliakrilamidnogo gelia.