Tinea capitis in Siena, Italy. An 18-year survey.
In the period 1980-1998, 181 cases of tinea capitis out of a total of 1480 cases of dermatophytosis were observed in Siena, Italy; 176 cases were children (mean age 6 years, range 45 days to 14 years; 91 boys, 85 girls) and the other five cases were postmenopausal women. Diagnosis was made on the basis of culture which was positive in 179 cases, and direct microscopic observation which was positive in 155 of 179 cases. In two cases, positive direct microscopic results were not confirmed by the culture. The most frequently isolated mycete was Microsporum canis (162 cases, 90.5%) and the main source of infection was the cat, which was often a healthy carrier. The second most frequent mycete was Trychophyton mentagrophytes. Trichophyton violaceum, a dermatophyte practically absent from our province since the 1960s, was isolated in five patients. All patients were successfully treated. One adult was treated with oral ketoconazole and the other four with oral itraconazole. The children were all treated with griseofulvin and topical antimycotics. Two children, observed in 1997-1998, who did not respond to griseofulvin, achieved clinical and mycological recovery with oral itraconazole.
Romano
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Istituto di Scienze Dermatologiche, Università degli Studi di Siena, Italy.
D000293:Adolescent; D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use; D002415:Cats; D002648:Child; D002675:Child, Preschool; D004285:Dogs; D005260:Female; D006118:Griseofulvin / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007558:Italy / Q000453:epidemiology; D017964:Itraconazole / Q000627:therapeutic use; D007654:Ketoconazole / Q000627:therapeutic use; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011817:Rabbits; D012189:Retrospective Studies; D014006:Tinea Capitis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology
D000935:Antifungal Agents; D017964:Itraconazole; D006118:Griseofulvin; D007654:Ketoconazole