title: Stent placement of gastroenteric anastomoses formed by magnetic compression.
abstract: OBJECTIVE
  To evaluate the use of stents for prolonging the patency of gastroenteric anastomoses (GEA) induced by magnet compression.
  
  
  METHODS
  Rare earth magnets were inserted perorally and serially in 15 dogs so as to mate across the gastric and jejunal walls. After magnet excretion, the resulting GEA was identified endoscopically, dilated (n = 1), and stented with bare (n = 2) or partially covered (n = 6) flared 10-mm or 12-mm Z stents. The GEA was followed at 2-4-week intervals for patency; malfunctioning shunts were irrigated, or dilated with angioplasty balloons. Gross and histologic examination of the anastomotic tissues was performed in 14 animals.
  
  
  RESULTS
  Magnet pairs were excreted in 5-7 days. Of the 19 magnet placements in 15 animals, stent placement was not possible because of early GEA closure (n = 6), failure to locate (n = 2), pancreatic abscess (n = 1), and magnet perforation with peritonitis (n = 1). Estimated duration of GEA patency was 19 days after balloon dilation, 40-64 days with bare Z stents, and 58-147 days (mean, 90 days) with partially covered Z stents. Shunt function was commonly hindered by bezoars. Stent narrowing or occlusion was caused by tissue overgrowth through bare stents (n = 2), between covered stent struts and through partially detached membrane (n = 2). Serious morbidity (n = 2) was due to malpositioned magnets across the pancreas in one animal and gastric perforation in the other. One dog was euthanized because of unsuspected kidney infection.
  
  
  CONCLUSIONS
  Partially covered stents significantly extend the anatomic patency rate of magnetic GEA to 7 weeks or more. Functional patency is frequently impaired by bezoars. Ongoing improvements in covered stent design should provide longer-term GEA patency.
authors.affiliation: Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA. cope@oasis.rad.upenn.edu
authors.forename: C
authors.initials: C
authors.lastname: Cope
authors.forename: T W
authors.initials: TW
authors.lastname: Clark
authors.forename: G
authors.initials: G
authors.lastname: Ginsberg
authors.forename: P
authors.initials: P
authors.lastname: Habecker
mesh_terms: D000800:Angioplasty, Balloon; D000818:Animals; D020099:Coated Materials, Biocompatible; D004285:Dogs; D005260:Female; D005763:Gastroenterostomy / Q000379:methods*; D005773:Gastroscopy; D007583:Jejunum / Q000000981:diagnostic imaging / Q000601:surgery*; D008280:Magnetics; D008674:Metals, Rare Earth; D019919:Prosthesis Implantation; D011859:Radiography; D015607:Stents; D013270:Stomach / Q000000981:diagnostic imaging / Q000601:surgery*
chemical_list: D020099:Coated Materials, Biocompatible; D008674:Metals, Rare Earth