CDC64 encodes cytoplasmic alanyl-tRNA synthetase, Ala1p, of Saccharomyces cerevisiae.
The cdc64-1 mutation causes G(1) arrest in Saccharomyces cerevisiae corresponding to a type II Start phenotype. We report that CDC64 encodes Ala1p, an alanyl-tRNA synthetase. Thus, cdc64-1 might affect charging of tRNA(Ala) and thereby initiation of cell division.
Wrobel
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C
MGH Cancer Center, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.
Schmidt
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EV
Polymenis
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D000412:Alanine-tRNA Ligase / Q000235:genetics*; D002455:Cell Division / Q000235:genetics; D016193:G1 Phase / Q000235:genetics; D005800:Genes, Fungal; D010641:Phenotype; D012441:Saccharomyces cerevisiae / Q000201:enzymology* / Q000235:genetics
D000412:Alanine-tRNA Ligase