Low-grade endometrial stromal sarcoma with cardiovascular involvement--a report of three cases.
BACKGROUND
In low-grade endometrial stromal sarcoma, it has been reported that vascular space involvement in surgical specimens is found in over 50% of patients. However, in contrast to intravenous leiomyomatosis, it has been thought that further tumor extension to large vessels is rarely observed.


METHODS
We present three cases of low-grade endometrial stromal sarcoma with cardiovascular involvement by recurrent tumors observed on imaging studies. Two cases demonstrated tumor infiltration inside the inferior vena cava while the other case showed tumor growth in the left ventricle.


CONCLUSIONS
This report suggests that attention should be paid to the possibility of cardiovascular invasion during the entire course of this disease.
Tabata
T
T
Department of Gynecology, Cancer Institute Hospital, 1-37-1, Kami-Ikebukuro, Toshima-ku, Tokyo, 170-8455, Japan.
Takeshima
N
N
Hirai
Y
Y
Hasumi
K
K
D000328:Adult; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D018203:Sarcoma, Endometrial Stromal / Q000473:pathology*