title: Cytokinesis: an emerging unified theory for eukaryotes?
abstract: In animal and fungal cells, cytokinesis involves an actomyosin ring that forms and contracts at the division plane. Important new details have emerged concerning the composition, assembly, and dynamics of these contractile rings. In addition, recent advances suggest that targeted membrane addition is a central feature of cytokinesis in animal cells - as it is in fungi and plants - and the coordination of actomyosin ring function with targeted exocytosis at the cleavage plane is being explored. Important new information has also emerged about the spatial and temporal regulation of cytokinesis, especially in relation to the function of the spindle midzone in animal cells and the control of cytokinesis by GTPase systems.
authors.affiliation: Department of Biology and Program in Molecular Biology and Biotechnology, University of North Carolina, Chapel Hill, NC 27599-3280, USA. kghales@email.unc.edu.
authors.forename: K G
authors.initials: KG
authors.lastname: Hales
authors.forename: E
authors.initials: E
authors.lastname: Bi
authors.forename: J Q
authors.initials: JQ
authors.lastname: Wu
authors.forename: J C
authors.initials: JC
authors.lastname: Adam
authors.forename: I C
authors.initials: IC
authors.lastname: Yu
authors.forename: J R
authors.initials: JR
authors.lastname: Pringle
mesh_terms: D000818:Animals; D002455:Cell Division; D004023:Dictyostelium / Q000166:cytology; D004330:Drosophila / Q000166:cytology; D020558:GTP Phosphohydrolases / Q000502:physiology; D008870:Microtubules / Q000502:physiology; D012441:Saccharomyces cerevisiae / Q000166:cytology; D012568:Schizosaccharomyces / Q000166:cytology; D013997:Time Factors
chemical_list: D020558:GTP Phosphohydrolases