title: Production of a TEM-24 plasmid-mediated extended-spectrum beta-lactamase by a clinical isolate of Pseudomonas aeruginosa.
abstract: Several Pseudomonas aeruginosa strains, including one urinary isolate producing an extended-spectrum beta-lactamase TEM-24, were isolated from a long-term-hospitalized woman. Three TEM-24-producing enterobacterial species (Enterobacter aerogenes, Escherichia coli, and Proteus mirabilis) were isolated from the same patient. TEM-24 and the resistance markers for aminoglycosides, chloramphenicol, and sulfonamide were encoded by a 180-kb plasmid transferred by conjugation into E. coli HB101.
authors.affiliation: Service de Bactériologie, Hôpital Arnaud de Villeneuve, 34295 Montpellier Cedex 5, France. h-marchandin@chu-montpellier.fr
authors.forename: H
authors.initials: H
authors.lastname: Marchandin
authors.forename: H
authors.initials: H
authors.lastname: Jean-Pierre
authors.forename: C
authors.initials: C
authors.lastname: De Champs
authors.forename: D
authors.initials: D
authors.lastname: Sirot
authors.forename: H
authors.initials: H
authors.lastname: Darbas
authors.forename: P F
authors.initials: PF
authors.lastname: Perigault
authors.forename: C
authors.initials: C
authors.lastname: Carriere
mesh_terms: D003227:Conjugation, Genetic; D004352:Drug Resistance, Microbial; D016521:Electrophoresis, Gel, Pulsed-Field; D004926:Escherichia coli / Q000235:genetics; D005260:Female; D006801:Humans; D010957:Plasmids; D011550:Pseudomonas aeruginosa / Q000235:genetics*; D001618:beta-Lactamases / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics*
chemical_list: D001618:beta-Lactamases