[Efficacy and tolerance of a calcium-magnesium-aspartate solution in the treatment of hypocalcemic parturient paresis in cows].
The systemic tolerance of a solution of calcium aspartate and magnesium aspartate was studied in 7 cows. Intravenously administered dosages of 500 ml per cow were well tolerated. A twofold increase of the serum calcium concentration was measured. In 2 cows which were treated with 1000 ml of the solution a threefold increased calcium concentration and heart arrhythmia were found. The clinical efficacy of the solution was demonstrated in a study with 44 hypocalcemic cows. A long lasting increase of the serum calcium as well as an enhanced phosphorus concentration were measurable. In conclusion, the calcium-magnesium-aspartate solution seems to be an efficacious and well tolerated alternative for the treatment of hypocalcemia in cows.
Andresen
U
U
Institut für Pharmakologie, Toxikologie und Pharmazie, Tierärztlichen Hochschule Hannover.
Kietzmann
M
M
Andresen
P
P
D000818:Animals; D001224:Aspartic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D017610:Calcium Compounds / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D005260:Female; D006996:Hypocalcemia / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D017616:Magnesium Compounds / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D010319:Parturient Paresis / Q000150:complications / Q000188:drug therapy*; D011247:Pregnancy; D012996:Solutions
D017610:Calcium Compounds; D017616:Magnesium Compounds; D012996:Solutions; D001224:Aspartic Acid
Zur Wirksamkeit und Verträglichkeit einer Kalzium-Magnesium-Aspartat-Lösung bei der Behandlung der hypokalzämischen Gebärparese des Rindes.