title: Transcriptional map of chromosome region 6q16-->q21.
abstract: We present the transcription map of chromosome region 6q16-->q21 by mapping fifteen known genes within this region. Five genes lay in the subregion containing a tumor suppressor gene, eight genes are located in the subregion harboring a senescence gene, and two genes are distal to the latter region. The precise location of the genes was obtained using a previously described translocation and deletion mouse/human hybrid panel. An even more accurate definition was possible for the genes spanning the senescence gene region, since a previously described YAC contig with its restriction map was available. From this transcription map it is possible to derive a large region of synteny with mouse chromosome 10.
authors.affiliation: Department of Experimental and Diagnostic Medicine, Section of Microbiology, Interdepartment Center for Biotechnology, University of Ferrara, Ferrara, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Karayianni
authors.forename: C
authors.initials: C
authors.lastname: Magnanini
authors.forename: V
authors.initials: V
authors.lastname: Orphanos
authors.forename: M
authors.initials: M
authors.lastname: Negrini
authors.forename: G M
authors.initials: GM
authors.lastname: Maniatis
authors.forename: D H
authors.initials: DH
authors.lastname: Spathas
authors.forename: G
authors.initials: G
authors.lastname: Barbanti-Brodano
authors.forename: C
authors.initials: C
authors.lastname: Morelli
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D018244:Chromosomes, Artificial, Yeast; D002896:Chromosomes, Human, Pair 6; D016147:Genes, Tumor Suppressor; D005819:Genetic Markers; D006801:Humans; D051379:Mice; D014158:Transcription, Genetic
chemical_list: D005819:Genetic Markers