Regiospecific internal desaturation of aliphatic compounds by a mutant Rhodococcus strain.
A mutant Rhodococcus strain lacking the ability to utilize 1-chlorohexadecane was found to cis-desaturate aliphatic compounds, such as 1-chlorohexadecane, n-hexadecane, and heptadecanonitrile, yielding corresponding products with a double bond mainly at the ninth carbon from the terminal methyl groups. A new oxidative pathway involving the cis-desaturation step was suggested for alkane utilization by Rhodococcus spp.
Koike
K
K
Tochigi Research Laboratories of Kao Corporation, Ichikai, Haga, Tochigi 321-3497, Japan. 381128@kastanet.kao.co.jp
Ara
K
K
Adachi
S
S
Takigawa
H
H
Mori
H
H
Inoue
S
S
Kimura
Y
Y
Ito
S
S
D000473:Alkanes / Q000378:metabolism; D006838:Hydrocarbons / Q000378:metabolism*; D006843:Hydrocarbons, Chlorinated / Q000378:metabolism*; D013058:Mass Spectrometry; D009154:Mutation; D009570:Nitriles / Q000378:metabolism; D012240:Rhodococcus / Q000235:genetics* / Q000378:metabolism*; D017550:Spectroscopy, Fourier Transform Infrared
D000473:Alkanes; D006838:Hydrocarbons; D006843:Hydrocarbons, Chlorinated; D009570:Nitriles; C007932:n-hexadecane; C039858:1-chlorohexadecane