Nuclear magnetic resonance monitoring of treatment and prediction of outcome in multiple sclerosis.
Magnetic resonance (MR) techniques provide an objective, sensitive and quantitative assessment of the evolving pathology in multiple sclerosis. There is an increasing definition of the pathological specificity of newer techniques, and more robust correlations with clinical evolution are emerging. As the pathophysiological basis of in vivo nuclear MR signal abnormalities is further elucidated, it is likely that the importance of MR as a tool to monitor new therapies will increase.
Miller
D H
DH
Institute of Neurology, London, UK.
Thompson
A J
AJ
D002986:Clinical Trials as Topic; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000628:therapy*; D010865:Pilot Projects; D011379:Prognosis; D012107:Research Design