[Autoantibodies against NMDA-receptors in the blood of patients with acute disorders of cerebral circulation].
Concentration of autoantibodies to human brain NMDA-receptor in blood serum of patients with acute brain ischemic stroke was significantly higher than in healthy persons and patients with other neurological diseases. Average content of cholesterol, lipid peroxides and glutamate in the serum were close in all patient groups investigated. It was suggested that the content of autoantibodies to human brain NMDA-receptor could be used as biochemical criteria for acute brain stroke patient's condition control and their treatment efficiency.
Denisenko
T V
TV
Institute of the Human Brain RAS, Saint-Petersburg Medical University.
Skuliabin
D I
DI
Gromov
I A
IA
Cherkas
Iu V
IuV
Iliukhina
A Iu
AIu
Dambinova
S A
SA
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001323:Autoantibodies / Q000097:blood*; D002561:Cerebrovascular Disorders / Q000097:blood / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016194:Receptors, N-Methyl-D-Aspartate / Q000276:immunology*
D001323:Autoantibodies; D016194:Receptors, N-Methyl-D-Aspartate
Autoantitela k NMDA-retseptoram v krovi bol'nykh s ostrymi narusheniiami mozgovogo krovoobrashcheniia.