Stimulative effect of dietary protein on the phosphorylation of p70 S6 kinase in the skeletal muscle and liver of food-deprived rats.
The effect of dietary protein on p70S6k phosphorylation was examined in rats starved for 18 h and then fed either a 20% casein diet (20C) or a protein-free diet (0C). Refeeding the 20C diet, but not the 0C diet, increased p70S6k phosphorylation in both the skeletal muscle and liver. The plasma insulin concentrations were the same after refeeding the 20C or 0C diet, suggesting that a combination of dietary protein and insulin may be required to stimulate p70S6k phosphorylation.
Yoshizawa
F
F
Department of Science of Living, Morioka Junior College, Iwate Prefectural University, Japan. fumiaki@iwate-pu.ac.jp
Kido
T
T
Nagasawa
T
T
D000818:Animals; D002364:Caseins / Q000378:metabolism; D004044:Dietary Proteins / Q000008:administration & dosage / Q000494:pharmacology*; D005508:Food Deprivation; D015151:Immunoblotting; D007328:Insulin / Q000097:blood; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D018482:Muscle, Skeletal / Q000187:drug effects / Q000201:enzymology*; D010766:Phosphorylation / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D019893:Ribosomal Protein S6 Kinases / Q000378:metabolism*; D013997:Time Factors
D002364:Caseins; D004044:Dietary Proteins; D007328:Insulin; D019893:Ribosomal Protein S6 Kinases