title: Subcorneal pustular dermatosis and IgA lambda myeloma: a uncommon association but probably not coincidental.
abstract: The present report deals with a case of subcorneal pustular dermatosis (SCPD) associated with IgAlambda myeloma and reviews the literature for similar cases. Three relevant points arise from this case: the association of the dermatosis with an IgAlambda myeloma that, as far as we know, has been described only three times previously; the longest period of time between the onset of the dermatosis and that of the myelopathy observed up to now; the good therapeutic response to etretinate, useful in the management of severe recalcitrant forms of SCPD.
authors.affiliation: University of Messina, Institute of Dermatology Policlinico Universitario, via Consolare Valeria Gazzi, 98125 Messina, Italy. Mario.Vaccaro@unime.it
authors.forename: M
authors.initials: M
authors.lastname: Vaccaro
authors.forename: S P
authors.initials: SP
authors.lastname: Cannavò
authors.forename: B
authors.initials: B
authors.lastname: Guarneri
mesh_terms: D000368:Aged; D005050:Etretinate / Q000627:therapeutic use; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007146:Immunoglobulin lambda-Chains; D008297:Male; D009101:Multiple Myeloma / Q000150:complications* / Q000276:immunology; D012872:Skin Diseases, Vesiculobullous / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
chemical_list: D007070:Immunoglobulin A; D007146:Immunoglobulin lambda-Chains; D005050:Etretinate