ALFRED: an allele frequency database for diverse populations and DNA polymorphisms.
We have developed a publicly accessible database (ALFRED, the ALlele FREquency Database) that catalogues allele frequency data for a wide range of population samples and DNA polymorphisms. This database is web-accessible through our laboratory (Kidd Lab) Web site: http://info.med.yale.edu/genetics/kkidd. ALFRED currently contains data on 60 populations and 156 genetic systems including single nucleotide polymorphisms (SNPs), short tandem repeat polymorphisms (STRPs), variable number of tandem repeats (VNTRs) and insertion-deletion polymorphisms. While data are not available for all population-DNA polymorphism combinations, over 2000 allele frequency tables have been entered. Our database is designed (i) to address our specific research requirements as well as broader scientific objectives; (ii) to allow researchers and interested educators to easily navigate and retrieve data of interest to them; and (iii) to integrate links to other related public databases such as dbSNP, GenBank and PubMed.
Cheung
K H
KH
Center for Medical Informatics, Yale University School of Medicine, 333 Cedar Street, PO Box 208009, New Haven, CT 06520-8009, USA.
Osier
M V
MV
Kidd
J R
JR
Pakstis
A J
AJ
Miller
P L
PL
Kidd
K K
KK
D000483:Alleles; D016208:Databases, Factual; D005787:Gene Frequency; D014644:Genetic Variation; D006801:Humans; D011110:Polymorphism, Genetic; D014584:User-Computer Interface