Transcriptional map of chromosome region 6q16-->q21.
We present the transcription map of chromosome region 6q16-->q21 by mapping fifteen known genes within this region. Five genes lay in the subregion containing a tumor suppressor gene, eight genes are located in the subregion harboring a senescence gene, and two genes are distal to the latter region. The precise location of the genes was obtained using a previously described translocation and deletion mouse/human hybrid panel. An even more accurate definition was possible for the genes spanning the senescence gene region, since a previously described YAC contig with its restriction map was available. From this transcription map it is possible to derive a large region of synteny with mouse chromosome 10.
Karayianni
E
E
Department of Experimental and Diagnostic Medicine, Section of Microbiology, Interdepartment Center for Biotechnology, University of Ferrara, Ferrara, Italy.
Magnanini
C
C
Orphanos
V
V
Negrini
M
M
Maniatis
G M
GM
Spathas
D H
DH
Barbanti-Brodano
G
G
Morelli
C
C
D000818:Animals; D002874:Chromosome Mapping; D018244:Chromosomes, Artificial, Yeast; D002896:Chromosomes, Human, Pair 6; D016147:Genes, Tumor Suppressor; D005819:Genetic Markers; D006801:Humans; D051379:Mice; D014158:Transcription, Genetic
D005819:Genetic Markers