title: Serum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breast.
abstract: Five of 43 patients (11.6%) with ductal carcinoma in situ of the breast presented with p53 autoantibodies at diagnosis. Three seropositive patients demonstrated tumour sizes of < or = 5 mm. There was no association of p53 autoantibody status with age, clinical presentation, histological subtype, tumour size, grading, p53 immunohistochemistry or hormone receptor status.
authors.affiliation: University of Ulm, Department of Obstetrics and Gynaecology, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Regele
authors.forename: P
authors.initials: P
authors.lastname: Kohlberger
authors.forename: F D
authors.initials: FD
authors.lastname: Vogl
authors.forename: W
authors.initials: W
authors.lastname: Böhm
authors.forename: R
authors.initials: R
authors.lastname: Kreienberg
authors.forename: I B
authors.initials: IB
authors.lastname: Runnebaum
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001323:Autoantibodies / Q000097:blood*; D001943:Breast Neoplasms / Q000276:immunology* / Q000473:pathology; D002278:Carcinoma in Situ / Q000276:immunology*; D018270:Carcinoma, Ductal, Breast / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008875:Middle Aged; D016159:Tumor Suppressor Protein p53 / Q000032:analysis / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D016159:Tumor Suppressor Protein p53