title: Infrequent microsatellite instability in papillary carcinomas of the thyroid.
abstract: The aim of the present study was to confirm the frequency of microsatellite instability in thyroid cancers. We investigated 26 patients suffering from thyroid cancer (25 papillary carcinomas, 1 follicular carcinoma) using 8 microsatellite markers. Microsatellite instability (MSI) was found in two (7.7%) papillary carcinomas. Our data indicate that MSI is a relatively rare event and may seldom contribute to the carcinogenesis of papillary carcinomas of the thyroid.
authors.affiliation: Department of Otorhinolaryngology, Hiroshima University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D000368:Aged; D002291:Carcinoma, Papillary / Q000235:genetics* / Q000556:secondary; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000235:genetics; D008297:Male; D018895:Microsatellite Repeats; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000235:genetics*