title: Effect of four dental varnishes on the colonization of cariogenic bacteria on exposed sound root surfaces.
abstract: The aim of this study was to evaluate the effect of four different dental varnishes on the colonization of mutans streptococci, total streptococci and lactobacilli on exposed sound root surfaces. Sixty-five individuals were randomly allotted to one of four groups for treatment with Cervitec((R) ) varnish containing 1% chlorhexidine and 1% thymol, a thymol varnish or one of two different fluoride varnishes, Fluor Protector and Duraphat. The varnish was applied to three buccal root surfaces in each patient at baseline and after 1 week. Dental plaque from the root surfaces was collected and analysed on four different occasions: at baseline, after 1 week, 1 month and 6 months. The Cervitec varnish caused a statistically significant reduction in the number of mutans streptococci over time. The reduction was significant at 1 week and 1 month relative to baseline. The numbers of total streptococci and lactobacilli were not significantly affected by treatment with Cervitec. No statistically significant difference over time was found for mutans streptococci, lactobacilli or total streptococci after treatment with the fluoride varnishes or the thymol varnish.
authors.affiliation: Department of Immunology, Microbiology, Pathology and Infectious Diseases, Karolinska Institute, Huddinge University Hospital, Huddinge, Sweden.
authors.forename: S B
authors.initials: SB
authors.lastname: Ekenbäck
authors.forename: L E
authors.initials: LE
authors.lastname: Linder
authors.forename: H
authors.initials: H
authors.lastname: Lönnies
mesh_terms: D000704:Analysis of Variance; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002327:Cariostatic Agents / Q000008:administration & dosage*; D002710:Chlorhexidine / Q000008:administration & dosage; D015169:Colony Count, Microbial; D003731:Dental Caries / Q000382:microbiology / Q000517:prevention & control*; D003773:Dental Plaque / Q000382:microbiology; D004338:Drug Combinations; D005460:Fluorides, Topical / Q000008:administration & dosage*; D006801:Humans; D007764:Lacquer; D007778:Lactobacillus / Q000187:drug effects; D011140:Polyurethanes; D012463:Saliva / Q000382:microbiology; D012821:Silanes; D012969:Sodium Fluoride; D018709:Statistics, Nonparametric; D013295:Streptococcus mutans / Q000187:drug effects; D013943:Thymol; D014092:Tooth Root / Q000382:microbiology*
chemical_list: D000891:Anti-Infective Agents, Local; D002327:Cariostatic Agents; D004338:Drug Combinations; D005460:Fluorides, Topical; D011140:Polyurethanes; D012821:Silanes; C079161:chlorhexidine, thymol drug combination; C023807:sodium fluoride topical preparation; D013943:Thymol; C022599:Fluor Protector; D012969:Sodium Fluoride; D002710:Chlorhexidine