Single fraction radiotherapy for bone metastases: are all questions answered?
All randomized trials show comparable pain relief rates with single or fractionated radiotherapy (RT) in selected patients. Further studies are required to determine the optimal single dose (our analysis suggests 6-8 Gy), its efficacy in preventing fractures/cord compression and defining criteria for recommending fractionated RT for a select few. Besides this, a 'lingua franca' for pain assessment tools is urgently required.
Chander
S S
SS
Department of Radiation Onocology, Tata Memorial Hospital, Parel, Mumbai, India.
Sarin
R
R
D001859:Bone Neoplasms / Q000150:complications / Q000532:radiotherapy* / Q000556:secondary*; D019583:Dose Fractionation, Radiation; D006801:Humans; D010146:Pain / Q000209:etiology / Q000532:radiotherapy; D010147:Pain Measurement; D010166:Palliative Care