Mechanical property predictions for polymorphs of sulphathiazole and carbamazepine.
The mechanical properties of polymorphs of sulphathiazole and carbamazepine have been determined experimentally by three-point beam bending. It is shown that the mechanical properties of sulphathiazole and carbamazepine polymorphs can be predicted using the atom-atom potential model applied to lattice dynamics, as long as account is taken of crystal morphology when considering the experimental results.
Roberts
R J
RJ
ZENECA Pharmaceuticals, Silk Road Business Park, Charter Way, Macclesfield, Cheshire, UK. ron.roberts@alderley.zaneca.com
Payne
R S
RS
Rowe
R C
RC
D002220:Carbamazepine / Q000737:chemistry*; D003460:Crystallization; D018360:Crystallography, X-Ray; D004338:Drug Combinations; D008855:Microscopy, Electron, Scanning; D000077589:Sulfathiazole; D013432:Sulfathiazoles / Q000737:chemistry*
D004338:Drug Combinations; D013432:Sulfathiazoles; D002220:Carbamazepine; D000077589:Sulfathiazole