[The role of the NMDA receptors in the creating of amblyopia].
The present state of knowledge concerning the etiopathogenesis of amblyopia is discussed. The morphological and functional changes taking place in the neuronal system of the Brodmann's 17th area during the amblyopia creation are described. The factors affecting the primary and secondary visual cortex are characterized. Special attention was focused on the N-methyl-D-aspartate (NMDA) receptors. Their structure and function is described. The role of the NMDA receptors in the formation of the visual cortex plasticity is discussed. The necessity of amblyopia treatment before the critical period is over has been pointed out. The possibilities of using the newest experimental results in amblyopia treatment are indicated.
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Katedry Okulistyki z Klinika i Zakładem Patofizjologii, Narzadu Wzroku Pomorskiej AM w Szczecinie.
D000550:Amblyopia / Q000209:etiology*; D006801:Humans; D009473:Neuronal Plasticity / Q000502:physiology; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology*; D014793:Visual Cortex / Q000502:physiology*
D016194:Receptors, N-Methyl-D-Aspartate
Rola receptorów NMDA w powstawaniu niedowidzenia.