title: Vocal cord paralysis after subtotal oesophagectomy.
abstract: BACKGROUND
  Although vocal cord paralysis is a well known complication of subtotal oesophagectomy, precise data concerning origin, incidence and associated morbidity are lacking.
  
  
  METHODS
  A retrospective study was performed of 241 patients who underwent transhiatal oesophagectomy for carcinoma of the mid/distal oesophagus between 1994 and 1998. Preoperative and postoperative laryngoscopy results were available for 140 patients.
  
  
  RESULTS
  There were 109 men and 31 women, of mean age 63 years. Thirty-one patients (22 per cent) with recurrent laryngeal nerve paralysis were identified, three with bilateral and 28 with unilateral dysfunction. Paralysis occurred ipsilateral to the side of the cervical incision in 22 of 28 patients. It was permanent in six patients. The associated morbidity was substantial: pulmonary complications were more common in patients with vocal cord paralysis (12 of 31 versus 26 (24 per cent) of 109), leading to significantly more reintubations, and a significantly prolonged ventilation time and stay in the intensive care unit.
  
  
  CONCLUSIONS
  Although mostly transient, vocal cord paralysis is a frequent complication with significant associated morbidity. In an extended transthoracic resection (including a lymphadenectomy in the aortopulmonary window where the left recurrent laryngeal nerve is at risk) the cervical anastomosis should be made on the left side, to minimize the risk of bilateral vocal cord paralysis.
authors.affiliation: Department of Surgery, Academic Medical Center/University of Amsterdam, The Netherlands.
authors.forename: J B
authors.initials: JB
authors.lastname: Hulscher
authors.forename: J W
authors.initials: JW
authors.lastname: van Sandick
authors.forename: P P
authors.initials: PP
authors.lastname: Devriese
authors.forename: J J
authors.initials: JJ
authors.lastname: van Lanschot
authors.forename: H
authors.initials: H
authors.lastname: Obertop
mesh_terms: D004938:Esophageal Neoplasms / Q000601:surgery; D016629:Esophagectomy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D014826:Vocal Cord Paralysis / Q000209:etiology*