title: Human retroviral sequences associated with extracellular particles in autoimmune diseases: epiphenomenon or possible role in aetiopathogenesis?
abstract: Publications describing retroviral sequences associated with extracellular particles in Sjögren's syndrome or systemic lupus erythematosus, multiple sclerosis, and type I diabetes present novel arguments and raise complex questions about eventual relationships between retroviruses and autoimmunity. They are presented and discussed in the present review, preceded by an overview of the biology of retroviral elements.
authors.affiliation: BioMérieux SA, Chemin de l'Orme 69280 Marcy l'Etoile, France.
authors.forename: H
authors.initials: H
authors.lastname: Perron
authors.forename: J M
authors.initials: JM
authors.lastname: Seigneurin
mesh_terms: D000818:Animals; D001172:Arthritis, Rheumatoid / Q000821:virology; D001327:Autoimmune Diseases / Q000821:virology*; D003922:Diabetes Mellitus, Type 1 / Q000821:virology; D020077:Endogenous Retroviruses / Q000145:classification / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D019143:Evolution, Molecular; D016679:Genome, Viral; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000821:virology; D009103:Multiple Sclerosis / Q000821:virology; D018626:Retroelements; D012190:Retroviridae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D012859:Sjogren's Syndrome / Q000821:virology; D014771:Virion / Q000235:genetics / Q000502:physiology
chemical_list: D018626:Retroelements