title: Designing secondary structures: 5-azidomethyl tetrahydrofuran-2-carboxylates as carbohydrate-derived dipeptide isosteres.
abstract: The potential of carbohydrate-like tetrahydrofuran frameworks as building blocks with predictable conformational propensities useful in the design and synthesis of novel peptidomimetic materials which adopt well-defined secondary structures is discussed.
authors.affiliation: University of Oxford, The Dyson Perrins Laboratory, Oxford Centre for Molecular Sciences, UK.
authors.forename: M D
authors.initials: MD
authors.lastname: Smith
authors.forename: G W
authors.initials: GW
authors.lastname: Fleet
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D001671:Biochemistry / Q000379:methods; D002241:Carbohydrates / Q000737:chemistry; D015195:Drug Design; D005663:Furans / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D018716:Molecular Mimicry; D015394:Molecular Structure; D010455:Peptides / Q000737:chemistry* / Q000494:pharmacology; D017433:Protein Structure, Secondary
chemical_list: D000596:Amino Acids; D002241:Carbohydrates; D005663:Furans; D010455:Peptides; C018674:tetrahydrofuran