title: Dynamic contrast-enhanced MRI in the differentiation of breast tumors: user-defined versus semi-automated region-of-interest analysis.
abstract: Dynamic contrast-enhanced MR mammography is an increasingly used method of evaluating breast pathology. The purpose of this study was to compare two semi-automated methods of region of interest (ROI) analysis with a user-defined method, in the discrimination of breast tumors using dynamic contrast-enhanced MRI. Results are presented from the retrospective analysis of 81 malignant and 36 benign breast lesions. The study demonstrates the importance of a consistent ROI strategy and also shows that semi-automated approaches offer a standardized method, which may improve the discrimination of primary breast tumors. J. Magn. Reson. Imaging 1999; 10:945-949.
authors.affiliation: Academic Department of Radiology, University of Hull, Hull HU6 7RX, United Kingdom. g.p.liney@medschool.hull.ac.uk
authors.forename: G P
authors.initials: GP
authors.lastname: Liney
authors.forename: P
authors.initials: P
authors.lastname: Gibbs
authors.forename: C
authors.initials: C
authors.lastname: Hayes
authors.forename: M O
authors.initials: MO
authors.lastname: Leach
authors.forename: L W
authors.initials: LW
authors.lastname: Turnbull
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis; D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis*; D002278:Carcinoma in Situ / Q000175:diagnosis; D018275:Carcinoma, Lobular / Q000175:diagnosis; D018276:Carcinoma, Medullary / Q000175:diagnosis; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis; D005348:Fibrocystic Breast Disease / Q000175:diagnosis; D005355:Fibrosis; D005500:Follow-Up Studies; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012189:Retrospective Studies; D012598:Sclerosis
chemical_list: D003287:Contrast Media