title: Locking of metacarpophalangeal joints in a patient with acromegaly.
abstract: A 39-year-old man with acromegaly exhibited locking of metacarpophalangeal (MCP) joints of both index fingers. Large osteophytes were found at the metacarpal heads by radiography and computerized tomography (CT). Magnetic resonance (MR) images revealed hypertrophy of volar plates. We suggest that these characteristic acromegalic features caused locking of MCP joints. Surgery was required on one of the joints to release the locking.
authors.affiliation: Department of Orthopaedic Surgery, Soseikai General Hospital, Hiroosa-cho 1, Shimotoba, Fushimi-ku, Kyoto 612-8473, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Tani
authors.forename: N
authors.initials: N
authors.lastname: Tanaka
authors.forename: E
authors.initials: E
authors.lastname: Isoya
mesh_terms: D000172:Acromegaly / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D015415:Biomarkers / Q000097:blood; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D007592:Joint Diseases / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008662:Metacarpophalangeal Joint / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D015415:Biomarkers; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone