Some new terms for duplicated genes.
If we are to investigate the relationships between genes, which can involve complex combinations of duplication, deletion and speciation, we need precise terminology. The terms 'paralogy' and 'orthology' have proved very useful in distinguishing two different relationships between homologous genes. Some relationships, however, are not included in either of these terms. I propose three new terms, for use in situations in which one or both lineages that lead to two present-day genes involve gene duplications.
Sharman
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AC
School of Animal and Microbial Sciences, University of Reading, UK. asharman@current.biology.com
D000818:Animals; D020440:Gene Duplication; D018398:Homeodomain Proteins; D006801:Humans; D051379:Mice; D009124:Muscle Proteins / Q000235:genetics; D009419:Nerve Tissue Proteins / Q000235:genetics; D051857:Otx Transcription Factors; D051763:PAX7 Transcription Factor; D010802:Phylogeny; D012689:Sequence Homology, Nucleic Acid; D009626:Terminology as Topic; D015534:Trans-Activators / Q000235:genetics; D014157:Transcription Factors
D018398:Homeodomain Proteins; D009124:Muscle Proteins; D009419:Nerve Tissue Proteins; D051857:Otx Transcription Factors; D051763:PAX7 Transcription Factor; C497322:Pax7 protein, mouse; D015534:Trans-Activators; D014157:Transcription Factors