title: Pharyngeal pouch carcinoma: real or imaginary risks?
abstract: Pharyngeal pouch or Zenker's diverticulum presents to the otolaryngologist with symptoms of dysphagia. As supported by the published literature, the condition is more frequently seen in Northern Europe, especially the United Kingdom, than elsewhere in the world. The cause of the reported increased incidence in the United Kingdom is not known, but may be dietary. Surgical management is the treatment of choice and is directed at the cricopharyngeus muscle by either an external or an internal approach. There is a real risk of carcinoma or carcinoma in situ developing in a treated or untreated pharyngeal pouch. Excision of the pouch sac is recommended in younger patients, less than 65 years, and in patients who have a large pouch. If endoscopic diverticulotomy is performed, then long-term patient symptom follow-up is to be advocated.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital, Queen's Medical Centre, Nottingham, England.
authors.forename: P J
authors.initials: PJ
authors.lastname: Bradley
authors.forename: A
authors.initials: A
authors.lastname: Kochaar
authors.forename: M S
authors.initials: MS
authors.lastname: Quraishi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002278:Carcinoma in Situ / Q000150:complications / Q000453:epidemiology / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000453:epidemiology / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D016672:Zenker Diverticulum / Q000150:complications / Q000473:pathology* / Q000601:surgery