title: Attempted chemoprophylaxis of cryptosporidiosis in chickens, using diclazuril, toltrazuril, or garlic extract.
abstract: Three battery tests were conducted to study the anticryptosporidial efficacy of the 2 commercially available anticoccidial triazinone derivates, diclazuril and toltrazuril, and a garlic extract. At the recommended level, diclazuril reduced the oocyst output of birds by 14.6%. The efficacy of toltrazuril was 52.1% at the recommended level, which could be moderately increased using 5 or 10 times the recommended dose. However, these doses resulted in significant weight gain reduction. The efficacy of garlic extract was 24.4%. It is concluded that none of the drugs can be recommended for chemoprophylaxis or therapy of cryptosporidiosis in chickens.
authors.affiliation: Department of Parasitology and Zoology, University of Veterinary Science, Budapest, Hungary.
authors.forename: T
authors.initials: T
authors.lastname: Sréter
authors.forename: Z
authors.initials: Z
authors.lastname: Széll
authors.forename: I
authors.initials: I
authors.lastname: Varga
mesh_terms: D000818:Animals; D002645:Chickens / Q000469:parasitology*; D003049:Coccidiostats / Q000627:therapeutic use*; D003457:Cryptosporidiosis / Q000517:prevention & control / Q000662:veterinary*; D005243:Feces / Q000469:parasitology; D005737:Garlic / Q000627:therapeutic use*; D008297:Male; D009570:Nitriles / Q000627:therapeutic use*; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D010946:Plants, Medicinal; D011201:Poultry Diseases / Q000517:prevention & control*; D014227:Triazines / Q000627:therapeutic use*; D015430:Weight Gain
chemical_list: D003049:Coccidiostats; D009570:Nitriles; D010936:Plant Extracts; D014227:Triazines; C057884:diclazuril; C036670:toltrazuril