title: Endocardial abscesses in children: case report and review of the literature.
abstract: The rarity of perivalvular abscesses arising as a complication of bacterial endocarditis in the pediatric population limits its recognition and awareness of its often malignant course. The diagnosis depends on a combination of clinical criteria, including persistent fever and bacteremia, the presence of an atrioventricular block and persistent embolic phenomenon, and transthoracic or transesophageal echocardiographic confirmation. Because of the infrequency of perivalvular abscesses in children, there is no consensus on a treatment strategy. Early detection and intervention with antibiotics and surgical debridement are recommended to decrease the morbidity and mortality associated with this disease. A case of a 14-year-old boy with an aortic root abscess is presented, along with review of other cases reported in the last 20 years in children in relation to risk factors, clinical features, diagnosis, therapy, and mortality.
authors.affiliation: Divisions of Pediatric Infectious Diseases,Montefiore Medical Center, Bronx, NY 10467, USA.
authors.forename: F S
authors.initials: FS
authors.lastname: Shah
authors.forename: G
authors.initials: G
authors.lastname: Fennelly
authors.forename: J
authors.initials: J
authors.lastname: Weingarten-Arams
authors.forename: L
authors.initials: L
authors.lastname: Yang
authors.forename: J
authors.initials: J
authors.lastname: Glickstein
mesh_terms: D000038:Abscess / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001021:Aortic Valve / Q000382:microbiology / Q000601:surgery; D002648:Child; D017548:Echocardiography, Transesophageal; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D013203:Staphylococcal Infections / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D013210:Staphylococcus / Q000187:drug effects / Q000302:isolation & purification; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin