title: Perfluoro-N-octane (PFO) in the repair of complicated retinal detachments due to severe proliferative diabetic retinopathy.
abstract: OBJECTIVE
  To report our experience with perfluoro-N-octane (PFO) in the surgical management of complicated retinal detachments due to proliferative diabetic retinopathy.
  
  
  METHODS
  Retrospective review of 18 consecutive eyes of 18 patients with tractional or combined tractional and rhegmatogenous retinal detachments due to severe proliferative diabetic retinopathy managed by pars plana vitrectomy and the intraoperative use of PFO. Preoperative characteristics, intraoperative findings and procedures and postoperative results were recorded.
  
  
  RESULTS
  The mean preoperative acuity was 2/200 (range, 20/25 to light perception). The mean final visual acuity was 4/200 (range, 20/20 to no light perception). With a mean follow-up of 6 months, there was an 89% anatomic reattachment rate at the last visit and visual acuity was stable or improved in 72% of eyes.
  
  
  CONCLUSIONS
  In our experience, PFO is a helpful surgical adjunct in the anatomic reattachment of tractional or combined tractional and rhegmatogenous diabetic retinal detachments. Visual acuity was stabilized or improved in the majority of eyes.
authors.affiliation: Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.
authors.forename: R K
authors.initials: RK
authors.lastname: Maturi
authors.forename: P T
authors.initials: PT
authors.lastname: Merrill
authors.forename: M D
authors.initials: MD
authors.lastname: Lomeo
authors.forename: R
authors.initials: R
authors.lastname: Diaz-Rohena
authors.forename: M
authors.initials: M
authors.lastname: Khan
authors.forename: H M
authors.initials: HM
authors.lastname: Lambert
mesh_terms: D000328:Adult; D003930:Diabetic Retinopathy / Q000150:complications* / Q000175:diagnosis; D005466:Fluorocarbons / Q000008:administration & dosage*; D006801:Humans; D007267:Injections; D007432:Intraoperative Period; D017075:Laser Coagulation; D008875:Middle Aged; D012163:Retinal Detachment / Q000209:etiology / Q000601:surgery*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods
chemical_list: D005466:Fluorocarbons; C073608:perfluorooctane