title: Asymmetric expression of antivin/lefty1 in the early chick embryo.
abstract: Mammalian lefty and zebrafish antivin, highly related to lefty, are shown to be expressed asymmetrically and involved in the specification of the left body side of early embryos. We isolated a chick homologue of the antivin/lefty1 cDNA and studied its expression pattern during early chick development. We found that antivin/lefty1 is expressed asymmetrically on the left side of the prospective floorplate, notochord and lateral plate mesoderm of the chick embryo.
authors.affiliation: Department of Biological Science and Technology, Faculty of Engineering, The University of Tokushima, 2-1 Minami-Jyosanjima-cho, Tokushima, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Ishimaru
authors.forename: H
authors.initials: H
authors.lastname: Yoshioka
authors.forename: H
authors.initials: H
authors.lastname: Tao
authors.forename: B
authors.initials: B
authors.lastname: Thisse
authors.forename: C
authors.initials: C
authors.lastname: Thisse
authors.forename: C
authors.initials: C
authors.lastname: V E Wright
authors.forename: H
authors.initials: H
authors.lastname: Hamada
authors.forename: H
authors.initials: H
authors.lastname: Ohuchi
authors.forename: S
authors.initials: S
authors.lastname: Noji
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D016764:Cell Polarity; D002642:Chick Embryo; D004625:Embryo, Nonmammalian / Q000196:embryology / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental; D055458:Left-Right Determination Factors; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D016212:Transforming Growth Factor beta / Q000096:biosynthesis / Q000235:genetics*
chemical_list: D055458:Left-Right Determination Factors; D016212:Transforming Growth Factor beta