title: Ascites produced in rats without tubercle bacilli or tumor cells.
abstract: Intraperitoneal injection of rats with two doses of pertussis vaccine produces a small amount of ascitic fluid. Much larger amounts of fluid are produced when two spaced injections of the vaccine are preceded by a small amount of liquid petrolatum. A similar result is obtained by a single injection of pertussis vaccine emulsified in liquid petrolatum and Arlacel A. Ascites produced without tubercle bacilli or tumor cells may increase the use of rats for antibody production.
authors.affiliation: Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA.
authors.forename: S
authors.initials: S
authors.lastname: Levine
authors.forename: A
authors.initials: A
authors.lastname: Saltzman
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000373:Agglutinins / Q000096:biosynthesis / Q000276:immunology; D000473:Alkanes / Q000008:administration & dosage; D000818:Animals; D000956:Antigens, Viral / Q000276:immunology; D001201:Ascites / Q000139:chemically induced / Q000209:etiology* / Q000276:immunology; D005260:Female; D005620:Freund's Adjuvant / Q000008:administration & dosage; D007274:Injections, Intraperitoneal; D009374:Neoplasms, Experimental / Q000276:immunology*; D010567:Pertussis Vaccine / Q000008:administration & dosage / Q000276:immunology*; D010577:Petrolatum / Q000008:administration & dosage; D051381:Rats; D011917:Rats, Inbred Lew; D013729:Terpenes / Q000008:administration & dosage
chemical_list: D000276:Adjuvants, Immunologic; D000373:Agglutinins; D000473:Alkanes; D000956:Antigens, Viral; D010567:Pertussis Vaccine; D013729:Terpenes; C009042:pristane; D010577:Petrolatum; D005620:Freund's Adjuvant; C007932:n-hexadecane