Oleogranulomatous response in lymph nodes associated with emollient use in Netherton's syndrome.
Paraffin-based emollients are widely used in dermatological practice and are not usually absorbed through the skin. We report a case where transcutaneous transfer did occur in the context of damaged skin in Netherton's syndrome, resulting in a reversible lymphadenopathy.
Cockayne
S E
SE
Department of Dermatology, Royal Hallamshire Hospital, Sheffield, UK.
Lee
J A
JA
Harrington
C I
CI
D000293:Adolescent; D004643:Emollients / Q000009:adverse effects* / Q000627:therapeutic use; D015745:Granuloma, Foreign-Body / Q000209:etiology* / Q000473:pathology; D006801:Humans; D016113:Ichthyosiform Erythroderma, Congenital / Q000473:pathology* / Q000628:therapy; D008198:Lymph Nodes / Q000473:pathology*; D012869:Skin Absorption
D004643:Emollients