Role of surgery in thymic disorders.
Thymomas are relatively slow-growing neoplasms that should be considered malignant tumours. When treated in the early stages, however, they have an excellent prognosis for long-term survival. Surgery, radiation therapy and chemotherapy all play a role in the management of these neoplasms. Surgery is the treatment of choice in thymoma patients and has become an increasingly accepted procedure in the treatment of myasthenia gravis (MG) since 1936, when thymectomy was performed for this disease for the first time. Improvement in myasthenic symptoms is nearly always observed following thymectomy, but the rates of complete remission vary from 7% to 63%. We have studied the potential preoperative factors predicting the evolution of MG.
Persico
G
G
Institute of General Surgery and Gastroenterology, and Department of Molecular and Clinical Endocrinology and Oncology, Faculty of Medicine and Surgery, University Federico II, Naples, Italy.
Martignetti
A
A
Imbriani
A
A
Montella
L
L
Aprea
G
G
Coto
M
M
Persico
F
F
Palmieri
G
G
D005260:Female; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000601:surgery; D009367:Neoplasm Staging; D011379:Prognosis; D016019:Survival Analysis; D013945:Thymoma / Q000401:mortality / Q000601:surgery*; D013950:Thymus Gland / Q000601:surgery; D013953:Thymus Neoplasms / Q000401:mortality / Q000601:surgery*