[Electron microscope study of lung carcinoid].
123 lung carcinoids were studied, 32 of them electron-microscopically. Ultrastructural features were evaluated with the use of multivariate analysis. The most informative ultrastructural features were the following: correlation between differentiated and undifferentiated cells, the number of cytoplasm organoids including endocrine granules, degree of nuclei polymorphism and their size, specialized contacts, mitoses. Up to 18% of carcinoids, on the average, need ultrastructural verification of the anaplasia degree, this percentage increasing to 27.2% in atypical carcinoids. The above ultrastructural criteria allow to specify malignant potential of carcinoids, facilitate differential diagnosis and make their prognosis.
Raĭklin
N T
NT
N. N. Blokhin Cancer Research Center, Moscow.
Smirnova
E A
EA
Polotskiĭ
B E
BE
Glazkova
T G
TG
Bebezov
B Kh
BKh
Davydov
M I
MI
D002276:Carcinoid Tumor / Q000401:mortality / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D011379:Prognosis; D016019:Survival Analysis
Elektronno-mikroskopicheskoe issledovanie kartsinoidov legkogo.