A case of herpes-like Sweet's syndrome in acute myelogenous leukemia during treatment with G-CSF.
A 49-year-old patient with refractory acute myelogenous leukemia (AML) is described who developed fever and herpes-like skin lesions during treatment with G-CSF. Skin biopsies revealed dermal neutrophilic infiltrates compatible with the diagnosis of Sweet's syndrome. The fever and skin lesions disappeared completely after treatment with corticosteroids.
van Mook
W N
WN
Department of Internal Medicine, Atrium Medical Center, Heerlen, The Netherlands.
Fickers
M M
MM
van der Kley
J A
JA
Theunissen
P H
PH
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D003937:Diagnosis, Differential; D005334:Fever / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D016179:Granulocyte Colony-Stimulating Factor / Q000009:adverse effects*; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000150:complications* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000209:etiology / Q000628:therapy; D013256:Steroids; D016463:Sweet Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*
D000893:Anti-Inflammatory Agents; D013256:Steroids; D016179:Granulocyte Colony-Stimulating Factor