Facilitation of seizures in limbic epileptic rats by complex 1 microTesla magnetic fields.
On three separate sessions 24 male rats with histories of limbic epilepsy were exposed to 10 temporal configurations for 5 min. each of one of two patterns of magnetic fields. Their intensities averaged about 1 microTesla (microT). The numbers of Level 5 (Racine) seizures, inferred by the rat's rearing, rapid forelimb clonus, and falling, were statistically more frequent for the frequency-modulated (Thomas) pattern when its pixel duration and interstimulus presentation were 3 msec. The effectiveness of this temporal configuration was replicated in a second within-subjects experiment (n = 9) that directly compared the numbers of seizures during exposures to each of the two patterns and to a sham-field. These results suggest that brains with sensitive limbic systems might respond to weak magnetic fields, generated from multiple overlapping fields from communication and computer systems whose temporal derivatives emerge as complex sequences with pixel durations within the millisecond range.
Persinger
M A
MA
Department of Psychology, Laurentian University, Sudbury, Ontario, Canada. mpersinger@admin.laurentian.ca
Belanger-Chellew
G
G
D000818:Animals; D004195:Disease Models, Animal; D004574:Electromagnetic Fields; D008032:Limbic System / Q000503:physiopathology*; D018021:Lithium Chloride / Q000008:administration & dosage; D008297:Male; D010862:Pilocarpine / Q000008:administration & dosage; D051381:Rats; D017208:Rats, Wistar; D012640:Seizures / Q000139:chemically induced / Q000503:physiopathology*
D010862:Pilocarpine; D018021:Lithium Chloride