title: Duchenne muscular dystrophy and concomitant metastatic alveolar rhabdomyosarcoma.
abstract: The authors report the concomitant occurrence of Duchenne muscular dystrophy (DMD) and alveolar rhabdomyosarcoma (RMS). A 4-year-old boy presented with symptoms involving his neuromuscular system that affected primarily his left hip and leg. Duchenne muscular dystrophy was diagnosed. Seven months later, metastatic alveolar RMS in the ipsilateral pelvis was documented. The diagnosis of one major disorder affecting striated muscle (DMD) may have prevented the early detection of another (RMS).
authors.affiliation: Division of Pediatric Hematology/Oncology, All Children's Hospital, University of South Florida College of Medicine, St. Petersburg, USA.
authors.forename: H C
authors.initials: HC
authors.lastname: Rossbach
authors.forename: A
authors.initials: A
authors.lastname: Lacson
authors.forename: N H
authors.initials: NH
authors.lastname: Grana
authors.forename: J L
authors.initials: JL
authors.lastname: Barbosa
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008297:Male; D015080:Mesna / Q000008:administration & dosage; D020388:Muscular Dystrophy, Duchenne / Q000150:complications* / Q000175:diagnosis; D009367:Neoplasm Staging; D018232:Rhabdomyosarcoma, Alveolar / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D015080:Mesna; D007069:Ifosfamide