title: Consumption of a buckwheat protein extract retards 7,12-dimethylbenz[alpha]anthracene-induced mammary carcinogenesis in rats.
abstract: Female rats were examined for the effects of feeding buckwheat protein extract (BWPE) on the development of mammary tumor caused by administration of 7,12-dimethylbenz[alpha]anthracene. The percentage of rats with palpable mammary tumors and serum estradiol were lower in the BWPE-fed animals than the casein-fed ones, implying that BWPE intake retarded the mammary carcinogenesis by lowering serum estradiol.
authors.affiliation: Development, Health Care, Kissei Pharmaceutical Company, Matsumoto, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Kayashita
authors.forename: I
authors.initials: I
authors.lastname: Shimaoka
authors.forename: M
authors.initials: M
authors.lastname: Nakajoh
authors.forename: N
authors.initials: N
authors.lastname: Kishida
authors.forename: N
authors.initials: N
authors.lastname: Kato
mesh_terms: D015127:9,10-Dimethyl-1,2-benzanthracene / Q000494:pharmacology; D000818:Animals; D016588:Anticarcinogenic Agents / Q000008:administration & dosage*; D002364:Caseins / Q000008:administration & dosage; D004032:Diet; D004044:Dietary Proteins / Q000008:administration & dosage*; D004958:Estradiol / Q000097:blood; D019612:Fagopyrum / Q000737:chemistry*; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000139:chemically induced / Q000517:prevention & control*; D010940:Plant Proteins / Q000008:administration & dosage*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors
chemical_list: D016588:Anticarcinogenic Agents; D002364:Caseins; D004044:Dietary Proteins; D010940:Plant Proteins; D004958:Estradiol; D015127:9,10-Dimethyl-1,2-benzanthracene