title: [Clinical analysis of Pseudomonas aeruginosa bacteremia].
abstract: To determine the outcome of Pseudomonas aeruginosa bacteremia and to identify risk factors for these infections in our University hospital, 46 cases (65 episodes) of Pseudomonas aeruginosa bacteremia were retrospectively investigated. The most frequent underlying diseases or cases were from Emergency and Critical care center (18 cases, including 11 case of cerebrovascular accident and head injury) followed by hematologic malignancies (11 cases) but none of the HIV infection was included in this study. The overall crude mortality rate was 50% and mortality rate within the first 1 week was 17%. Clinical analysis of those cases revealed that possible risk factors were neutropenia, sever sepsis and prior use of antibiotics (antipseudomonal antibiotics were administered before positive blood culture episodes in 90% cases). But these factors were not statistically significant between dead and survived cases.
  
  
  CONCLUSIONS
  To improve the prognosis of Pseudomonas aeruginosa bacteremia, we must change the management of the hospital infection, such as the more rational use of new antipseudomonal antibiotics and the more clean and reasonable management of central venous catheters.
authors.affiliation: Department of Clinical Pathology, Nihon University School of Medicine, Tokyo.
authors.forename: K
authors.initials: K
authors.lastname: Kumasaka
authors.forename: N
authors.initials: N
authors.lastname: Hosokawa
authors.forename: M
authors.initials: M
authors.lastname: Yanai
authors.forename: M
authors.initials: M
authors.lastname: Yagoshi
authors.forename: K
authors.initials: K
authors.lastname: Simoguchi
authors.forename: K
authors.initials: K
authors.lastname: Kawano
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000209:etiology* / Q000401:mortality; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011552:Pseudomonas Infections / Q000209:etiology* / Q000401:mortality; D012189:Retrospective Studies; D012307:Risk Factors