title: Steroid transformations with Exophiala jeanselmei var. lecanii-corni and Ceratocystis paradoxa.
abstract: The fungi Exophiala jeanselmei var. lecanii-corni [IMI (International Mycological Institute) 312989, UAMH (University of Alberta Microfungus Collection and Herbarium) 8783] and Ceratocystis paradoxa (IMI 374529, UAMH 8784) have been examined for their potential in steroid biotransformation. The study has determined that E. jeanselmei var. lecanii-corni effected overall anti-Markovnikov hydration on dehydroisoandrosterone, and side-chain degradation on a variety of pregnanes. Both ascomycetes were found to carry out redox reactions of alcohols and ketones as well as 1,4 reduction of alpha,beta-unsaturated carbonyl systems.
authors.affiliation: Chemistry Department, University of the West Indies, Mona, Kingston, Jamaica.
authors.forename: R B
authors.initials: RB
authors.lastname: Porter
authors.forename: W A
authors.initials: WA
authors.lastname: Gallimore
authors.forename: P B
authors.initials: PB
authors.lastname: Reese
mesh_terms: D001203:Ascomycota / Q000378:metabolism*; D001711:Biotransformation; D005093:Exophiala / Q000378:metabolism*; D013057:Spectrum Analysis; D013256:Steroids / Q000737:chemistry / Q000378:metabolism*
chemical_list: D013256:Steroids