Dihydrochalcones and flavonolignans from Iryanthera lancifolia.
An extract from the pericarps of I. lancifolia afforded two dihydrochalcones (1 and 2) and two flavonolignans (3 and 4), with compounds 2-4 being of novel structure. The antioxidant activities of compounds 1-4 were evaluated through the measurement of malondialdehyde production, and Q(1/2) (concentration necessary for 50% inhibition of autoxidation) data were calculated. The Q(1/2) values obtained for 1-4 and the standard compounds alpha-tocopherol and quercetin were 6.9, 4.7, 5.5, 4.8, 12.1, and 7.6 microg/mL, respectively.
Silva
D H
DH
Instituto de Qu¿imica, Universidade de Såo Paulo, C.P. 26077, CEP 05599-970, Såo Paulo-SP, Brazil, Instituto de Qu¿imica, Universidade Estadual Paulista, C.P. 355, CEP 14800-900, Araraquara-SP, Brazil, and Faculdade de Ci¿enc. dhsilva@iq.unesp.br
Davino
S C
SC
Barros
S B
SB
Yoshida
M
M
D000818:Animals; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D001923:Brain Chemistry / Q000187:drug effects; D001938:Brazil; D002240:Carbohydrate Sequence; D002599:Chalcone / Q000031:analogs & derivatives / Q000737:chemistry* / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry* / Q000494:pharmacology; D017705:Lignans / Q000737:chemistry* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D017392:Thiobarbituric Acid Reactive Substances / Q000737:chemistry
D000975:Antioxidants; D005419:Flavonoids; D017705:Lignans; D017392:Thiobarbituric Acid Reactive Substances; D002599:Chalcone