title: [Anticoagulants in clinical practice].
abstract: Four classes of anticoagulants are now available: vitamin K antagonists, heparin, Orgaran and hirudin. For each of these classes the mechanism of the anticoagulant effect, the usual doses and biological monitoring are described. Each low molecular weight heparin must be considered as an original product. Orgaran and hirudin are new antithrombotic agents allowing to solve the dramatic problems raised by heparin-induced thrombocytopenia.
authors.affiliation: Laboratoire d'hématologie, Hôpital de Rangueil, Toulouse.
authors.forename: B
authors.initials: B
authors.lastname: Boneu
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D002809:Chondroitin Sulfates / Q000627:therapeutic use; D003871:Dermatan Sulfate / Q000627:therapeutic use; D006493:Heparin / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D006497:Heparan Sulfate / Q000627:therapeutic use; D024764:Hirudin Therapy; D006801:Humans; D013921:Thrombocytopenia / Q000139:chemically induced; D014812:Vitamin K / Q000037:antagonists & inhibitors
chemical_list: D000925:Anticoagulants; D002809:Chondroitin Sulfates; D003871:Dermatan Sulfate; D006493:Heparin; D006497:Heparan Sulfate; D014812:Vitamin K; C035838:danaparoid
vernacular_title: Anticoagulants et leur maniement.