title: Does hospital at home for palliative care facilitate death at home? Randomised controlled trial.
abstract: OBJECTIVE
  To evaluate the impact on place of death of a hospital at home service for palliative care.
  
  
  METHODS
  Pragmatic randomised controlled trial.
  
  
  METHODS
  Former Cambridge health district.
  
  
  METHODS
  229 patients referred to the hospital at home service; 43 randomised to control group (standard care), 186 randomised to hospital at home.
  
  
  METHODS
  Hospital at home versus standard care.
  
  
  METHODS
  Place of death.
  
  
  RESULTS
  Twenty five (58%) control patients died at home compared with 124 (67%) patients allocated to hospital at home. This difference was not significant; intention to treat analysis did not show that hospital at home increased the number of deaths at home. Seventy three patients randomised to hospital at home were not admitted to the service. Patients admitted to hospital at home were significantly more likely to die at home (88/113; 78%) than control patients. It is not possible to determine whether this was due to hospital at home itself or other characteristics of the patients admitted to the service. The study attained less statistical power than initially planned.
  
  
  CONCLUSIONS
  In a locality with good provision of standard community care we could not show that hospital at home allowed more patients to die at home, although neither does the study refute this. Problems relating to recruitment, attrition, and the vulnerability of the patient group make randomised controlled trials in palliative care difficult. While these difficulties have to be recognised they are not insurmountable with the appropriate resourcing and setting.
authors.affiliation: Health Services Research Group, General Practice and Primary Care Research Unit, Department of Community Medicine, University of Cambridge, Institute of Public Health, Cambridge CB2 2SR. gag1001@medschl.cam.ac.uk
authors.forename: G E
authors.initials: GE
authors.lastname: Grande
authors.forename: C J
authors.initials: CJ
authors.lastname: Todd
authors.forename: S I
authors.initials: SI
authors.lastname: Barclay
authors.forename: M C
authors.initials: MC
authors.lastname: Farquhar
mesh_terms: D003643:Death; D004739:England; D018575:Home Care Services, Hospital-Based / Q000458:organization & administration*; D006801:Humans; D010166:Palliative Care / Q000458:organization & administration*; D012111:Residence Characteristics; D018401:Sample Size