Novel radicinol derivatives from long-term cultures of alternaria chrysanthemi
Cultures of Alternaria chrysanthemi normally produce radicinin (1) and radicinol (2) when cultured on Czapek-Dox medium or on potato dextrose broth. We have observed that long-term cultures of A. chrysanthemi grown on malt-extract broth produce 3-epiradicinol (3), the novel metabolites 3-methoxy-3-epiradicinol (4) and 9, 10-epoxy-3-methoxy-3-epiradicinol (5), and (2).
Sheridan
H
Department of Pharmacognosy School of Pharmacy, Trinity College, Dublin 2, Ireland.
Canning
AM