Analysis of antibiotics by capillary electrophoresis.
The broad category of antibiotics encompasses some of the most widely prescribed pharmaceuticals in the world. As is the case with any pharmaceutical, an antibiotic must be characterized in terms of its potency and the presence and quantity of impurities. Additionally, any residue or metabolite that may be present as a result of its use must be monitored. Many capillary electrophoretic techniques have been utilized in the analysis of antibiotics, addressing the various aspects of quantifying, profiling, and monitoring. Some of the more recent applications are summarized in this review article.
Flurer
C L
CL
Forensic Chemistry Center, US Food and Drug Administration, Cincinnati, OH 45237, USA. cflurer@ora.fda.gov
D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000097:blood / Q000652:urine; D002626:Chemistry, Pharmaceutical; D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods; D019075:Electrophoresis, Capillary / Q000379:methods*; D005504:Food Analysis; D006801:Humans
D000900:Anti-Bacterial Agents