title: [Pediatric regional anesthesia: rational approaches and practical aspects].
abstract: Regional anesthesia in children is to be carried out with due consideration for anatomy, physiology (specifically, neurophysiology), pharmacology of local anesthetics, and detailed knowledge of pediatric protocols of numerous regional blockades. Age-specific differences in the pharmacokinetics of local anesthetics should be borne in mind when choosing safe doses and protocols. The pharmacokinetic factors may involve the risk of toxic reactions to local anesthetics. The protocols of central neuroaxial blockades in children are characterized by certain differences, concerning the indications, anatomic reference points, choice of special equipment, doses, and schemes of administration.
authors.forename: S V
authors.initials: SV
authors.lastname: Razhev
authors.forename: S M
authors.initials: SM
authors.lastname: Stepanenko
authors.forename: O S
authors.initials: OS
authors.lastname: Geodakian
authors.forename: V A
authors.initials: VA
authors.lastname: Mikhel'son
mesh_terms: D000367:Age Factors; D015360:Analgesia, Epidural / Q000379:methods; D000700:Analgesics / Q000008:administration & dosage; D000701:Analgesics, Opioid / Q000008:administration & dosage; D000765:Anesthesia, Conduction / Q000379:methods; D000767:Anesthesia, Epidural / Q000379:methods; D000772:Anesthesia, Local / Q000379:methods; D000775:Anesthesia, Spinal / Q000009:adverse effects / Q000379:methods; D000779:Anesthetics, Local / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D000075202:Contraindications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007278:Injections, Spinal; D009020:Morphine / Q000008:administration & dosage; D010149:Postoperative Pain / Q000188:drug therapy
chemical_list: D000700:Analgesics; D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D009020:Morphine
vernacular_title: Pediatricheskaia regionarnaia anesteziia: ratsional'nye podkhody i prakticheskie aspekty.