Penicillium peritonitis in an adolescent receiving chronic peritoneal dialysis.
A 19-year-old female on chronic peritoneal dialysis developed acute peritonitis; multiple peritoneal fluid and catheter tip cultures yielded Penicillium species. She promptly responded to catheter removal and intravenous amphotericin B, followed by oral fluconazole, without further recurrences 1 year later. This is the first reported case of Penicillium peritonitis in the pediatric population. We review the microbiology and clinical spectrum of this disease, as well as the few previous reported cases in adults.
Equils
O
O
Department of Pediatrics, UCLA School of Medicine, 10833 Le Conte Avenue, MDCC 22-442, Los Angeles, CA 90095-1752, USA.
Deville
J G
JG
Shapiro
A M
AM
Sanchez
C P
CP
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D010407:Penicillium / Q000378:metabolism*; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010538:Peritonitis / Q000209:etiology* / Q000382:microbiology*
D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole