title: High-dose salvage chemotherapy. Germ-cell tumor treatment results in Germany.
abstract: During the past 10 years, high-dose chemotherapy (HDCT) has emerged as a feasible and curative treatment option for patients with multiply relapsed and/or refractory germ-cell tumors. Increasing experience and the results from clinical trials have helped to optimize the application of HDCT and to define its role in the salvage concepts for germ-cell tumors.
authors.affiliation: Abteilung für Hämatologie und Onkologie, Charité, Campus Virchow Klinikum, Berlin, Germany.
authors.forename: O
authors.initials: O
authors.lastname: Rick
authors.forename: W
authors.initials: W
authors.lastname: Siegert
authors.forename: J
authors.initials: J
authors.lastname: Beyer
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation; D016190:Carboplatin / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D005047:Etoposide / Q000008:administration & dosage; D005858:Germany; D018237:Germinoma / Q000188:drug therapy / Q000401:mortality / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008297:Male; D011379:Prognosis; D012008:Recurrence; D016879:Salvage Therapy; D015996:Survival Rate; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000628:therapy*; D013852:Thiotepa / Q000008:administration & dosage
chemical_list: D005047:Etoposide; D013852:Thiotepa; D016190:Carboplatin