Glomerulonephritis in a neonate with atypical congenital lupus and toxoplasmosis.
The development of glomerulonephritis as a complication of neonatal lupus or congenital toxoplasmosis is extremely rare. We report a case of membranous glomerulonephritis occurring in a neonate with toxoplasmosis and atypical congenital lupus, including high-titer antinuclear antibodies and hypocomplementemia. This case illustrates that glomerulonephritis in the neonate may be induced by passively transferred maternal antibodies.
Lam
C
C
Department of Pathology, Columbia University College of Physicians and Surgeons, 630 West 168 Street, New York, NY 10032, USA.
Imundo
L
L
Hirsch
D
D
Yu
Z
Z
D'Agati
V
V
D001485:Basement Membrane / Q000473:pathology / Q000648:ultrastructure; D005260:Female; D005920:Glomerular Mesangium / Q000473:pathology / Q000648:ultrastructure; D005921:Glomerulonephritis / Q000150:complications* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000151:congenital; D008297:Male; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D011247:Pregnancy; D014125:Toxoplasmosis, Congenital / Q000150:complications*