Studies on the serological cross-reaction between dengue and Japanese encephalitis.
Antibody responses of sero-confirmed flavivirus-infected patients were investigated by hemagglutination-inhibition (HI) tests against acute phase sera (S1) and convalescent phase sera (S2) using JE virus (JEV) JaGAr# 01 strain antigen (J-Ag) and dengue virus (DV) type 1 Hawaiian strain antigen (D-Ag). Analysis of the test results showed that depending on the combinations of HI responses to both antigens, the sero-confirmed patients could be divided into five classes: primary JE, secondary JE, primary D (JEV-uncontracted), primary D(JEV-contracted), and secondary D(JEV-contracted) patients. The diagnostic combinations of responses to HI tests for the infections were discussed and defined in this paper.
Chang
K J
KJ
National Institute of Preventive Medicine (NIPM), Department of Health, Executive Yuan, Taipei, Taiwan, R.O.C.
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D003429:Cross Reactions; D003715:Dengue / Q000175:diagnosis / Q000276:immunology*; D003937:Diagnosis, Differential; D004672:Encephalitis, Japanese / Q000175:diagnosis / Q000276:immunology*; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D013552:Swine
D000914:Antibodies, Viral