[Treatment of infectious complications of experimental acute radiation injury with combined antibiotic sulacillin].
An anti-infectious effect of sulacillin (ampicillin/sulbactam) is higher than that of ampicillin in treatment of irradiated mice infected with a beta-lactamaseproducing strain of Kl. pneumoniae. Involving of sulacillin as a principal antibiotic into the therapeutic scheme for acute radiation sickness results in 67% dogs survival at LD90/45.
Chertkov
K S
KS
State Research Centre of Russia-Institute of Biophysics, Moscow. ibphgen@rcibph.dol.ru
Revskaia
E A
EA
D000667:Ampicillin / Q000627:therapeutic use*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control*; D004285:Dogs; D004338:Drug Combinations; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000150:complications*; D013407:Sulbactam / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D000667:Ampicillin; C090243:sulacillin; D013407:Sulbactam
Lechenie infektsionnykh oslozhneniĭ éksperimental'noĭ ostroĭ luchevoĭ bolezni kombinirovannym antibiotikom sulatsillinom.