[Antibodies against nerve tissue proteins S100, GFAP, and MP65 and pregnant women with early toxemia].
Serum levels/affinities of natural autoantibodies to proteins S100, GFAP and MP65 in patients with physiological pregnancy are usually constant and may vary among individuals within relatively narrow range. In patients with early toxicosis in pregnancy dispersion of serum autoantibodies levels were often found beyond the normal range. This group includes cases with significantly elevated as well as abnormally decreased immunoreactivity parameters. Percent of newborns with different deviations from women with abnormal serum levels/affinities of autoantibodies to proteins S100, GFAP and MP65 was higher 1,5-2 fold compared with population.
Morozov
S G
SG
Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow.
Poletaev
A B
AB
Murashko
L E
LE
D'iakova
E P
EP
Ponomareva
I V
IV
Gnedenko
B B
BB
Sukhikh
G T
GT
D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000276:immunology*; D006801:Humans; D016023:Integrins / Q000276:immunology*; D008562:Membrane Glycoproteins / Q000276:immunology*; D011225:Pre-Eclampsia / Q000276:immunology*; D011247:Pregnancy; D009418:S100 Proteins / Q000276:immunology*
D001323:Autoantibodies; D005904:Glial Fibrillary Acidic Protein; D016023:Integrins; D008562:Membrane Glycoproteins; D009418:S100 Proteins; C025363:mannoproteins
Antitela k belkam nervnoĭ tkani S100, GFAP, MP65 u beremennykh s rannim toksikozom.