Controlled Fas ligand gene expression by Cre/loxP-mediated switching system: high levels of FasL expression result in lethal hepatitis.
Fujino
M
M
Department of Experimental Surgery and Bioengineering, National Children's Medical Research Center, Tokyo, Japan.
Okuyama
T
T
Li
X K
XK
Funeshima
N
N
Tamura
A
A
Enosawa
S
S
Amano
T
T
Amemiya
H
H
Suzuki
S
S
D000818:Animals; D017209:Apoptosis; D004926:Escherichia coli / Q000235:genetics; D053222:Fas Ligand Protein; D005786:Gene Expression Regulation / Q000276:immunology*; D018014:Gene Transfer Techniques; D006520:Hepatitis, Animal / Q000235:genetics / Q000276:immunology / Q000473:pathology*; D019426:Integrases / Q000235:genetics / Q000378:metabolism*; D008099:Liver / Q000473:pathology*; D008297:Male; D008562:Membrane Glycoproteins / Q000235:genetics*; D051379:Mice; D008807:Mice, Inbred BALB C; D011401:Promoter Regions, Genetic; D051381:Rats; D017384:Sequence Deletion; D014764:Viral Proteins; D001616:beta-Galactosidase / Q000096:biosynthesis / Q000235:genetics; D019014:fas Receptor / Q000276:immunology
D053222:Fas Ligand Protein; C505658:Fasl protein, mouse; C505662:Faslg protein, rat; D008562:Membrane Glycoproteins; D014764:Viral Proteins; D019014:fas Receptor; C045073:Cre recombinase; D019426:Integrases; D001616:beta-Galactosidase