title: [Atypical ductal hyperplasia of the breast. Its diagnostic imaging and the role of percutaneous needle biopsy with a 14-gauge needle].
abstract: OBJECTIVE
  To investigate the yield of core biopsy in the histologic characterization of atypical ductal hyperplasia (ADH) and to assess the radiological patterns, if any, of this condition.
  
  
  METHODS
  January 1993 to October 1997 we studied 553 lesions, 8 of them with a diagnosis of ADH made on microhistologic samples obtained with 14G needles. Biopsy was performed under US guidance in 81.7% of cases and under mammographic guidance in 18.3%. The breast lesions were studied with mammography, US and MRI, the latter in one case. ADH was diagnosed by strict application of Page's and lesion extent criteria.
  
  
  RESULTS
  Seven of 8 lesions with a core biopsy diagnosis of ADH were submitted to surgical biopsy. The diagnosis was changed in as many as 6 of 8 cases, into typical ductal hyperplasia (1 case) and carcinoma (1 papilliferous, 3 ductal infiltrating and 1 in situ lesions). ADH was confirmed in one case only.
  
  
  CONCLUSIONS
  In agreement with other authors, we found no specific radiological patterns of ADH. Moreover, the core biopsy diagnosis of ADH requires a surgical biopsy, because ADH is often associated with carcinoma.
  
  
  CONCLUSIONS
  Surgical biopsy is needed to diagnose ADH and therefore it is useless to perform more invasive procedures than 14G core biopsy.
authors.affiliation: Istituto di Radiologia, Università degli Studi, Udine.
authors.forename: M
authors.initials: M
authors.lastname: Bazzocchi
authors.forename: I
authors.initials: I
authors.lastname: Facecchia
authors.forename: C
authors.initials: C
authors.lastname: Zuiani
authors.forename: C
authors.initials: C
authors.lastname: di Loreto
authors.forename: F
authors.initials: F
authors.lastname: Puglisi
authors.forename: A
authors.initials: A
authors.lastname: Vasciaveo
mesh_terms: D001707:Biopsy, Needle / Q000295:instrumentation / Q000379:methods; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008327:Mammography; D009339:Needles; D012680:Sensitivity and Specificity; D016217:Ultrasonography, Mammary
vernacular_title: Iperplasia duttale atipica della mammella. Diagnostica per immagini e ruolo dell'agobiopsia percutanea con ago da 14 gauge.