Intermittent left coronary occlusion caused by native aortic valve thrombosis in a patient with protein S deficiency.
A 77-year-old woman presented with chest pain and cardiogenic shock. Transesophageal echocardiography showed a mobile mass occluding intermittently the left coronary ostium. The mass was surgically resected, and histologic examination revealed an organized thrombus. Coagulation study demonstrated a protein S deficiency. This is the first case of aortic thrombosis associated with protein S deficiency, and it is the first time that transesophageal echocardiography provided definite evidence that a mass can cause intermittent left ostium coronary obstruction.
Jobic
Y
Y
Department of Cardiology and Cardiac Surgery, Brest University Hospital, France.
Provost
K
K
Larlet
J M
JM
Mondine
P
P
Gilard
M
M
Boschat
J
J
Blanc
J J
JJ
D000368:Aged; D001021:Aortic Valve / Q000000981:diagnostic imaging; D006348:Cardiac Surgical Procedures; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D017548:Echocardiography, Transesophageal; D004562:Electrocardiography; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D017293:Protein S / Q000378:metabolism; D018455:Protein S Deficiency / Q000097:blood / Q000150:complications*; D013927:Thrombosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery
D017293:Protein S