Asymmetric expression of antivin/lefty1 in the early chick embryo.
Mammalian lefty and zebrafish antivin, highly related to lefty, are shown to be expressed asymmetrically and involved in the specification of the left body side of early embryos. We isolated a chick homologue of the antivin/lefty1 cDNA and studied its expression pattern during early chick development. We found that antivin/lefty1 is expressed asymmetrically on the left side of the prospective floorplate, notochord and lateral plate mesoderm of the chick embryo.
Ishimaru
Y
Y
Department of Biological Science and Technology, Faculty of Engineering, The University of Tokushima, 2-1 Minami-Jyosanjima-cho, Tokushima, Japan.
Yoshioka
H
H
Tao
H
H
Thisse
B
B
Thisse
C
C
V E Wright
C
C
Hamada
H
H
Ohuchi
H
H
Noji
S
S
D000595:Amino Acid Sequence; D000818:Animals; D016764:Cell Polarity; D002642:Chick Embryo; D004625:Embryo, Nonmammalian / Q000196:embryology / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental; D055458:Left-Right Determination Factors; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D016212:Transforming Growth Factor beta / Q000096:biosynthesis / Q000235:genetics*
D055458:Left-Right Determination Factors; D016212:Transforming Growth Factor beta