title: Mapping eddy current induced fields for the correction of diffusion-weighted echo planar images.
abstract: Diffusion-weighted echo-planar magnetic resonance imaging is potentially of great importance as a diagnostic imaging tool; however, the technique currently suffers a number of limitations, including the image distortion caused by the eddy current induced fields when the diffusion-weighting magnetic field gradient pulses are applied. The distortions cause mis-registration between images with different diffusion-weighting, that then results in artifacts in quantitative diffusion images. A method is presented to measure the magnetic fields generated from the eddy currents for each of three orthogonal gradient pulse vectors, and then to use these to ascertain the image distortion that occurs in subsequent diffusion-weighted images with arbitrary gradient pulse vector amplitude and direction, and image plane orientation. The image distortion can then be reversed. Both temporal and spatial dependence of the residual eddy current induced fields are included in the analysis. Image distortion was substantially reduced by the correction scheme, for arbitrary slice position and angulation. This method of correction is unaffected by the changes in image contrast that occur due to diffusion weighting, and does not need any additional scanning time during the patient scan. It is particularly suitable for use with single-shot echo planar imaging.
authors.affiliation: Division of Medical Physics, University of Leicester, Leicester Royal Infirmary, UK. mah5@le.ac.uk
authors.forename: M A
authors.initials: MA
authors.lastname: Horsfield
mesh_terms: D016880:Anisotropy; D001921:Brain / Q000033:anatomy & histology*; D004058:Diffusion; D017352:Echo-Planar Imaging / Q000379:methods* / Q000592:standards; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D019047:Phantoms, Imaging / Q000592:standards; D013997:Time Factors