Distal tubular dysfunction in lupus nephritis of childhood and adolescence.
We describe a girl with lupus nephritis who presented with distal renal tubular acidosis and hyporeninemic hypoaldosteronism. While distal tubular dysfunction is well recognized in adult systemic lupus erythematosus (SLE), only a few pediatric patients have been reported. Evaluation of five pediatric patients with SLE revealed that distal tubular dysfunction in childhood and adolescence is rare.
Hataya
H
H
Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160, Japan.
Ikeda
M
M
Ide
Y
Y
Kobayashi
Y
Y
Kuramochi
S
S
Awazu
M
M
D000141:Acidosis, Renal Tubular / Q000097:blood / Q000150:complications* / Q000473:pathology; D000293:Adolescent; D000450:Aldosterone / Q000097:blood; D002648:Child; D003404:Creatinine / Q000097:blood; D005260:Female; D005665:Furosemide / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006994:Hypoaldosteronism / Q000097:blood / Q000150:complications* / Q000473:pathology; D007668:Kidney / Q000648:ultrastructure; D008181:Lupus Nephritis / Q000097:blood / Q000150:complications* / Q000473:pathology; D008854:Microscopy, Electron; D011188:Potassium / Q000097:blood; D012083:Renin / Q000097:blood
D000450:Aldosterone; D005665:Furosemide; D003404:Creatinine; D012083:Renin; D011188:Potassium