Developmental expression of alloantigen systems in the chicken.
The different allelic forms of nine non-Mhc alloantigen systems of the chicken were examined for developmental expression on erythrocytes isolated from embryos and young chicks. Polyclonal alloantisera raised against the different antigens were used to detect these antigens on the cell surface by hemagglutination as well as by indirect immunofluorescence. The developmental stage of initial expression on erythrocytes for each of the genetic systems investigated (i.e., A, E, C, D, H, I, K, L and P) varied from day 4 to day 14 of incubation. The different antigens of each system appeared simultaneously at a particular stage of development except for those of the I system, where the I8 allelic form appeared earlier than I2.
Kopti
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F
Department of Biological Sciences, Northern Illinois University, DeKalb 60115, USA.
Stevens
S L
SL
Briles
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WE
D000818:Animals; D002642:Chick Embryo; D002645:Chickens / Q000254:growth & development / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology; D007518:Isoantibodies / Q000276:immunology; D007519:Isoantigens / Q000096:biosynthesis* / Q000276:immunology
D007518:Isoantibodies; D007519:Isoantigens