title: Esophageal cancer mortality and total hardness levels in Taiwan's drinking water.
abstract: The possible association between the risk of esophageal cancer and hardness levels in drinking water from municipal supplies was investigated in a matched case-control study in Taiwan. All eligible esophageal cancer deaths (2084 cases) of Taiwan residents from 1987 through 1996 were compared with deaths from other causes (2084 controls), and the hardness levels of the drinking water used by these residents were determined. Data on water hardness throughout Taiwan have been collected from the Taiwan Water Supply Corporation (TWSC). The control group consisted of people who died from other causes and the controls were pair-matched to the cases by sex, year of birth, and year of death. The results show that there is a 42% excess risk of mortality from esophageal cancer in relation to the use of soft water (adjusted odds ratio and 95% confidence intervals was 1.42 (1.22-1.66). This is an important finding for the Taiwan water industry and human health.
authors.affiliation: School of Public Health, Kaohsiung Medical College, Kaohsiung, Taiwan, Republic of China. chunyuh@cc.kmc.edu.tw
authors.forename: C Y
authors.initials: CY
authors.lastname: Yang
authors.forename: H F
authors.initials: HF
authors.lastname: Chiu
authors.forename: M F
authors.initials: MF
authors.lastname: Cheng
authors.forename: S S
authors.initials: SS
authors.lastname: Tsai
authors.forename: C F
authors.initials: CF
authors.lastname: Hung
authors.forename: M C
authors.initials: MC
authors.lastname: Lin
mesh_terms: D000368:Aged; D002118:Calcium / Q000032:analysis; D016022:Case-Control Studies; D004938:Esophageal Neoplasms / Q000209:etiology / Q000401:mortality*; D005260:Female; D006801:Humans; D008274:Magnesium / Q000032:analysis; D008297:Male; D008875:Middle Aged; D011634:Public Health; D018570:Risk Assessment; D013624:Taiwan / Q000453:epidemiology; D014881:Water Supply / Q000032:analysis*
chemical_list: D008274:Magnesium; D002118:Calcium