title: The SYSTERS protein sequence cluster set.
abstract: The SYSTERS (short for SYSTEmatic Re-Searching) protein sequence cluster set consists of the classification of all sequences from SWISS-PROT and PIR into disjoint protein family clusters and hierarchically into superfamily and subfamily clusters. The cluster set can be searched with a sequence using the SSMAL search tool or a traditional database search tool like BLAST or FASTA. Additionally a multiple alignment is generated for each cluster and annotated with domain information from the Pfam database of protein domain families. A taxonomic overview of the organisms covered by a cluster is given based on the NCBI taxonomy. The cluster set is available for querying and browsing at http://www.dkfz-heidelberg. de/tbi/services/cluster/systersform
authors.affiliation: Deutsches Krebsforschungszentrum, Theoretische Bioinformatik, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. a.krause@dkfz-heidelberg.de
authors.forename: A
authors.initials: A
authors.lastname: Krause
authors.forename: J
authors.initials: J
authors.lastname: Stoye
authors.forename: M
authors.initials: M
authors.lastname: Vingron
mesh_terms: D000595:Amino Acid Sequence; D003628:Database Management Systems; D016208:Databases, Factual; D020407:Internet; D008969:Molecular Sequence Data; D011506:Proteins / Q000737:chemistry*; D017386:Sequence Homology, Amino Acid
chemical_list: D011506:Proteins