title: Mechanical property predictions for polymorphs of sulphathiazole and carbamazepine.
abstract: The mechanical properties of polymorphs of sulphathiazole and carbamazepine have been determined experimentally by three-point beam bending. It is shown that the mechanical properties of sulphathiazole and carbamazepine polymorphs can be predicted using the atom-atom potential model applied to lattice dynamics, as long as account is taken of crystal morphology when considering the experimental results.
authors.affiliation: ZENECA Pharmaceuticals, Silk Road Business Park, Charter Way, Macclesfield, Cheshire, UK. ron.roberts@alderley.zaneca.com
authors.forename: R J
authors.initials: RJ
authors.lastname: Roberts
authors.forename: R S
authors.initials: RS
authors.lastname: Payne
authors.forename: R C
authors.initials: RC
authors.lastname: Rowe
mesh_terms: D002220:Carbamazepine / Q000737:chemistry*; D003460:Crystallization; D018360:Crystallography, X-Ray; D004338:Drug Combinations; D008855:Microscopy, Electron, Scanning; D000077589:Sulfathiazole; D013432:Sulfathiazoles / Q000737:chemistry*
chemical_list: D004338:Drug Combinations; D013432:Sulfathiazoles; D002220:Carbamazepine; D000077589:Sulfathiazole