A comparison of post-thaw results between cryopreserved embryos derived from intracytoplasmic sperm injection and those from conventional IVF.
OBJECTIVE
To study the effect of freezing on early stage embryos derived from intracytoplasmic sperm injection (ICSI) or from IVF.


METHODS
Prospective, controlled clinical study.


METHODS
Private IVF center.


METHODS
Sixty-seven consecutive patients undergoing frozen-thawed embryo transfer cycles.


METHODS
Early stage embryos were frozen, thawed, and transferred.


METHODS
Post-thaw survival, implantation and pregnancy rates.


RESULTS
We noted an 88% post-thaw survival rate, an 18% implantation rate, and a 52% pregnancy rate in the ICSI group and 81%, 11%, and 25%, respectively, with conventional fertilization.


CONCLUSIONS
Early stage embryos (either zygote or 2-4 cells) derived from ICSI can be frozen with confidence and higher post-thaw survival and pregnancy rates can be achieved when compared with those from conventional IVF.
Hu
Y
Y
Northwest Center for Infertility and Reproductive Endocrinology, Margate, Florida, USA.
Maxson
W S
WS
Hoffman
D I
DI
Ory
S J
SJ
Eager
S
S
D000328:Adult; D015925:Cryopreservation; D010064:Embryo Implantation; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006358:Hot Temperature; D006801:Humans; D008423:Maternal Age; D011247:Pregnancy; D018873:Pregnancy Rate; D018566:Pregnancy, High-Risk; D020554:Sperm Injections, Intracytoplasmic