title: Efficacy of an inactivated oil emulsion vaccine against hydropericardium syndrome in broilers.
abstract: Two inactivated vaccines were prepared against hydropericardium syndrome. The vaccine prepared from liver homogenate extracted with chloroform, inactivated with formalin and adjuvanted with liquid paraffin was highly effective against challenge in chickens aged three, five and seven weeks. Seroconversion following vaccination and challenge was assessed by the agar gel immunodiffusion test. The inactivated oil emulsion vaccine was highly effective against the syndrome in both experimental trials and field trials.
authors.affiliation: Center for Animal Health Studies, Tamilnadu Veterinary and Animal Science University, Chennai, India.
authors.forename: P
authors.initials: P
authors.lastname: Roy
authors.forename: A
authors.initials: A
authors.lastname: Koteeswaran
authors.forename: R
authors.initials: R
authors.lastname: Manickam
mesh_terms: D000257:Adenoviridae Infections / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary; D000818:Animals; D002645:Chickens / Q000276:immunology*; D004655:Emulsions; D009821:Oils; D010490:Pericardial Effusion / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D010496:Pericardium / Q000473:pathology; D011201:Poultry Diseases / Q000276:immunology / Q000517:prevention & control*; D013577:Syndrome; D015164:Vaccines, Inactivated / Q000627:therapeutic use*
chemical_list: D004655:Emulsions; D009821:Oils; D015164:Vaccines, Inactivated