title: Aspergillus tracheobronchitis after allogeneic bone marrow transplantation.
abstract: We describe a patient who developed Aspergillus tracheobronchitis after BMT. She complained of progressive dyspnea on day +165 and her respiratory function deteriorated rapidly. Although neither early chest X-rays nor CT scans were negative, bronchoscopy revealed formation of a pseudomembrane around the bronchial walls. Based upon pathological and microbiological examinations, she was diagnosed as having invasive Aspergillus tracheobronchitis. Retrospectively analyzed, the Aspergillus circulating antigen detection tests became positive before clinical symptoms developed, and may be beneficial for early diagnosis of Aspergillus tracheobronchitis. This form of aspergillosis should be regarded as one of the serious complications after BMT.
authors.affiliation: The Department of Hematology and Oncology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: U
authors.initials: U
authors.lastname: Machida
authors.forename: M
authors.initials: M
authors.lastname: Kami
authors.forename: Y
authors.initials: Y
authors.lastname: Kanda
authors.forename: K
authors.initials: K
authors.lastname: Takeuchi
authors.forename: M
authors.initials: M
authors.lastname: Akahane
authors.forename: I
authors.initials: I
authors.lastname: Yamaguchi
authors.forename: C
authors.initials: C
authors.lastname: Kakiuchi
authors.forename: N
authors.initials: N
authors.lastname: Takeda
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Chiba
authors.forename: H
authors.initials: H
authors.lastname: Honda
authors.forename: H
authors.initials: H
authors.lastname: Hirai
mesh_terms: D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis / Q000209:etiology*; D001230:Aspergillus / Q000145:classification / Q000302:isolation & purification*; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy*; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000209:etiology*; D014184:Transplantation, Homologous