title: The impact of intraoperative autologous blood transfusion during type III radical hysterectomy for early-stage cervical cancer.
abstract: OBJECTIVE
  The aim of this study was to determine the effects on transfusion rates, perioperative complications, and survival of using intraoperative autologous blood transfusions for patients undergoing type III radical hysterectomy and lymphadenectomy.
  
  
  METHODS
  A retrospective analysis was conducted on 156 patients treated with type III radical hysterectomy and lymphadenectomy at the University of Miami School of Medicine from 1990 to 1997. One group of patients (n = 50) had intraoperative autologous blood transfusions and the other (n = 106) did not.
  
  
  RESULTS
  The group that received intraoperative autologous blood transfusion had a significant reduction in homologous blood transfusions (12% vs 30%; P =.02). Patient demographic data, histologic parameters, and operative factors were similar between the 2 groups. There was a higher percentage of patients with positive pelvic lymph nodes in the group that did not receive intraoperative autologous blood transfusion (10% vs 30%; P =.02). Seven patients in the intraoperative autologous blood transfusion group (14%) died with disease present and all the recurrences in this group were local.
  
  
  CONCLUSIONS
  The use of intraoperative autologous blood transfusions during type III radical hysterectomy and lymphadenectomy appears to be safe and effective without compromising rates and patterns of recurrence.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Miami School of Medicine/Jackson Memorial Medical Center 33136, USA.
authors.forename: R
authors.initials: R
authors.lastname: Mirhashemi
authors.forename: H E
authors.initials: HE
authors.lastname: Averette
authors.forename: K
authors.initials: K
authors.lastname: Deepika
authors.forename: R
authors.initials: R
authors.lastname: Estape
authors.forename: R
authors.initials: R
authors.lastname: Angioli
authors.forename: J
authors.initials: J
authors.lastname: Martin
authors.forename: M
authors.initials: M
authors.lastname: Rodriguez
authors.forename: M A
authors.initials: MA
authors.lastname: Penalver
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D000328:Adult; D001804:Blood Transfusion, Autologous; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D007432:Intraoperative Period; D008197:Lymph Node Excision; D008499:Medical Records; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D016019:Survival Analysis; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000601:surgery / Q000628:therapy*