Race and gender differences in cord blood lipoproteins.
Race and gender differences in lipoproteins and apolipoproteins have repeatedly been demonstrated in adults. The same disparities have been observed in children of different race and gender, implying that these differences may be influenced by genetic factors. To further explore this hypothesis, cord blood concentrations of both lipoproteins and apolipoproteins were examined in black and white neonates of both sexes. Results were controlled for the observed effects of gestational age and growth parameters. Similar patterns of lipoprotein differences to those observed in adults and children were also detected between black and white, and between male and female neonates. These findings support the concept that the aetiology of the difference in lipoprotein concentration observed between race and gender groups includes a significant genetic component.
Loughrey
C M
CM
Department of Laboratory Medicine, Children's Hospital, Harvard Medical School, 300 Longwood Ave., Boston, MA 02115, USA. clodagh.loughrey@a1.tch.harvard.edu
Rimm
E
E
Heiss
G
G
Rifai
N
N
D001053:Apolipoproteins / Q000097:blood; D044383:Black People; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D012727:Sex Characteristics; D044465:White People
D001053:Apolipoproteins; D008074:Lipoproteins