title: [Physiology of coronary circulation and angioplasty: utopia or clinical reality?].
abstract: Small pressure transducer and Doppler quartz placed at the tip of angioplasty guide wire give the opportunity to measure coronary flow physiology parameters, the physiopathologic impact of an epicardic coronary stenosis and the efficacy of its treatment. This gives the opportunity to over ride the coronary imaging limitations. Doppler and pressure investigate a different and complementary aspect of the pressure-flow relation and may be used together in some special cases. Myocardial fractional flow reserve (FFRmyo) and relative coronary reserve concepts allow to evaluate patients with heterogeneous coronary reserve. Clinical application field is very broad and can be applied to each step of coronary angioplasty from the evaluation of intermediate lesions and the indication of angioplasty to the guidance of the procedure to the evaluation of the result, through the stenting indication and the stent placement optimization. Numerous studies has emphasized the role of physiologic coronary assessment in the cathlab. The time and economic gain of such an attitude has to be confirmed by future trials but it is clear now that it is not possible to continue to take decision on the sol visual aspect of a lesion.
authors.affiliation: Unité de cardiologie interventionnelle, hôpital Henri-Mondor, Créteil.
authors.forename: P
authors.initials: P
authors.lastname: Dupouy
authors.forename: E
authors.initials: E
authors.lastname: Teiger
authors.forename: P
authors.initials: P
authors.lastname: Garot
authors.forename: G
authors.initials: G
authors.lastname: Pelle
authors.forename: E
authors.initials: E
authors.lastname: Aptecar
authors.forename: A
authors.initials: A
authors.lastname: Belardi
authors.forename: S
authors.initials: S
authors.lastname: el Amine
authors.forename: J M
authors.initials: JM
authors.lastname: Pernès
authors.forename: J L
authors.initials: JL
authors.lastname: Dubois-Randé
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation* / Q000379:methods; D003326:Coronary Circulation; D003327:Coronary Disease / Q000175:diagnosis* / Q000503:physiopathology; D003362:Cost-Benefit Analysis; D015150:Echocardiography, Doppler / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D015607:Stents; D018924:Vascular Capacitance
vernacular_title: La physiologie de la circulation coronaire et l'angioplastie: utopie ou réalité clinique?