Fifteen years' experience with an antirefluxing biliary drainage valve.
OBJECTIVE
The aim of this study was to examine the efficacy of the antirefluxing, mucosal-flap valve (AMFV) for biliary drainage relative to technical feasibility, surgical complications, and incidence of ascending cholangitis (AC).


METHODS
Twenty-seven infants requiring biliary tract reconstruction underwent valve construction. Twenty biliary atresia (BA) patients received the Kasai procedure, and 7 choledochal cyst (CC) infants had cystectomy and hepatoenterostomy. A retrospective review of all patients was performed including radiographic evaluation of the current valve function in 10 patients.


RESULTS
Construction was successful in all cases, and no morbidity was incurred by incorporation of the valve. Of 7 CC patients, there have been no known episodes of AC with mean follow-up of 4.4+/-4.2 years. Of 20 BA patients, there have been 5 deaths (25%), 7 liver transplants (35%), 2 (10%) lost to follow-up, and 6 (30%) survivors. Nine BA patients (45%) have had AC, with patients in all 4 outcome categories represented. Ten patients (5 CC and 5 BA) have been evaluated with barium small bowel radiographs, with no reflux to the liver hilum in all cases.


CONCLUSIONS
The AMFV has caused no morbidity and continues to prevent reflux to the liver hilum. Despite functioning as designed, it does not appear to influence the occurrence of AC. Because CC patients had no AC, we feel that infection is related to the underlying atresia rather than to reflux.
Bowles
B J
BJ
Department of Surgery, University of Hawaii School of Medicine, Honolulu.
Abdul-Ghani
A
A
Zhang
J
J
Shim
W K
WK
D001656:Biliary Atresia / Q000150:complications / Q000401:mortality / Q000601:surgery*; D002675:Child, Preschool; D002761:Cholangitis / Q000209:etiology* / Q000517:prevention & control; D004322:Drainage / Q000295:instrumentation; D005260:Female; D005500:Follow-Up Studies; D005764:Gastroesophageal Reflux / Q000517:prevention & control*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011171:Portoenterostomy, Hepatic / Q000379:methods* / Q000401:mortality; D019919:Prosthesis Implantation; D019651:Plastic Surgery Procedures / Q000379:methods; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome