Clinical and biological aspects of infection caused by Ehrlichia chaffeensis.
Ehrlichia chaffeensis is an obligatory intracellular bacterium that infects the monocyte-macrophage. E. chaffeensis, which is transmitted to humans by ticks primarily from infected deer, causes human monocytic ehrlichiosis, an acute febrile systemic illness. This paper reviews current knowledge of clinical and biological aspects of infections caused by E. chaffeensis.
Rikihisa
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Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, 1925 Coffey Road, Columbus, Ohio 43210, USA.
D000818:Animals; D001179:Arthropod Vectors / Q000382:microbiology; D006224:Cricetinae; D003870:Dermacentor / Q000382:microbiology; D018469:Ehrlichia chaffeensis / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity* / Q000648:ultrastructure; D016873:Ehrlichiosis / Q000453:epidemiology / Q000276:immunology* / Q000382:microbiology* / Q000469:parasitology; D006801:Humans