Low CSF soluble interleukin 2 receptor levels in acute depression. Short communication.
Thirteen patients with DSM-III-R diagnosis of either major depression or bipolar I depression participated in the study. The control group consisted of 10 subjects evaluated for headache or suspected meningitis, none of whom were found to suffer from any organic disease. CSF was withdrawn from all subjects for the measurement of soluble interleukin 2 receptor (sIL-2R). CSF sIL-2R levels were found to be lower in patients as compared to controls (df = 1, 20; F = 84; p<0.000001).
Levine
J
J
Beersheva Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Israel. levinej@msx.upmc.edu
Barak
Y
Y
Chengappa
K R
KR
Rapoport
A
A
Antelman
S M
SM
Barak
V
V
D000328:Adult; D000368:Aged; D003863:Depression / Q000097:blood / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000032:analysis* / Q000097:blood
D015375:Receptors, Interleukin-2