title: Adult-onset Still's disease with persistent plaques.
abstract: Adult-onset Still's disease (AOSD) is a systemic disorder characterized by intermittent fever, evanescent rash, arthralgias or arthritis and predominantly neutrophilic leucocytosis. We report on a 16-year-old woman with Still's disease who developed, in addition to the typical rash, persistent papular lesions on her face, neck and upper and lower back. Although the presence of fixed skin lesions is not a characteristic feature of AOSD, their appearance at the onset of the disease and their evolution suggest that they represent a specific manifestation of the disease.
authors.affiliation: Clinic and Policlinic of Dermatology, Hôpitaux Universitaires de Genève, Rue Micheli-du-Crest 24, CH 1211 Genève 14, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Lübbe
authors.forename: M
authors.initials: M
authors.lastname: Hofer
authors.forename: P
authors.initials: P
authors.lastname: Chavaz
authors.forename: J H
authors.initials: JH
authors.lastname: Saurat
authors.forename: L
authors.initials: L
authors.lastname: Borradori
mesh_terms: D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D011241:Prednisone / Q000627:therapeutic use; D017444:Skin Diseases, Papulosquamous / Q000188:drug therapy / Q000473:pathology*; D016706:Still's Disease, Adult-Onset / Q000188:drug therapy / Q000473:pathology*; D013997:Time Factors
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D001241:Aspirin; D011241:Prednisone