Comparative distribution of GABAergic and peptide-containing neurons in the lateral lemniscal nuclei of the rat.
By immunostaining, neurons expressing peptides (dynorphin and corticotropin-releasing factor, CRF) and glutamate decarboxylase (GAD), a GABA-synthesizing enzyme, were precisely mapped in the rat lateral lemniscal nuclei. While GAD neurons were numerous and preferably localized in the dorsal (DLL) and ventral (VLL) nuclei, neurons expressing these peptides were less numerous and localized primarily in the intermediate (ILL) nucleus of the lateral lemniscus. The ILL nucleus was shown to project to the inferior colliculus and to express Fos rapidly in response to peripheral acoustic stimulation, suggesting that the ILL nucleus may take part in non-GABAergic relay of acoustic information in the lateral lemniscus.
Ueyama
T
T
Department of Anatomy, Kansai Medical University, Moriguchi, Osaka 570-8506, Japan.
Sato
K
K
Kakimoto
S
S
Houtani
T
T
Sakuma
S
S
Ohishi
H
H
Kase
M
M
Sugimoto
T
T
D000818:Animals; D002552:Cerebral Ventricles / Q000187:drug effects / Q000502:physiology; D003078:Colchicine / Q000494:pharmacology; D003346:Corticotropin-Releasing Hormone / Q000378:metabolism*; D004399:Dynorphins / Q000378:metabolism*; D005968:Glutamate Decarboxylase / Q000378:metabolism*; D007276:Injections, Intraventricular; D008297:Male; D009474:Neurons / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D011149:Pons / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D005680:gamma-Aminobutyric Acid; D004399:Dynorphins; D003346:Corticotropin-Releasing Hormone; D005968:Glutamate Decarboxylase; D003078:Colchicine