title: A unique effect of clonazepam on frontal lobe seizure control.
abstract: In a 16-year-old female, clonazepam (CZP) changed randomly occurring intractable tonic seizures of frontal lobe origin to a few sleep seizures when used as an adjunctive therapy. The significance of this change in the seizure pattern is discussed with an explanation of possible pathophysiologic mechanism.
authors.affiliation: Neurology Sections, King Khalid and King Fahad National Guard Hospitals, Jeddah, Kingdom of Saudi Arabia.
authors.forename: T
authors.initials: T
authors.lastname: Obeid
authors.forename: A
authors.initials: A
authors.lastname: Awada
authors.forename: N
authors.initials: N
authors.lastname: Sayes
authors.forename: Y
authors.initials: Y
authors.lastname: Mousali
authors.forename: C
authors.initials: C
authors.lastname: Harris
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use*; D002998:Clonazepam / Q000627:therapeutic use*; D004829:Epilepsy, Generalized / Q000188:drug therapy*; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans
chemical_list: D000927:Anticonvulsants; D002998:Clonazepam