title: Effect of ethyl methane sulphonate on biomass and protein production by Candida tropicalis.
abstract: Large doses of ethyl methanesulphonate (EMS) greatly increased the induction of auxotrophic mutants in Candida tropicalis. The maximum yield of biomass and protein was recorded in some mutants isolated after treatment with 60, 80 and 100 ppm EMS. The electrophoretic protein profile revealed typical banding patterns for both C. tropicalis wild type and mutants.
authors.affiliation: Department of Molecular Genetics, Kumamoto University School of Medicine, Japan.
authors.forename: Y A
authors.initials: YA
authors.lastname: Mahmoud
mesh_terms: D018533:Biomass; D002175:Candida / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D005020:Ethyl Methanesulfonate / Q000494:pharmacology*; D005656:Fungal Proteins / Q000096:biosynthesis / Q000187:drug effects; D016296:Mutagenesis / Q000187:drug effects; D009153:Mutagens / Q000494:pharmacology*
chemical_list: D005656:Fungal Proteins; D009153:Mutagens; D005020:Ethyl Methanesulfonate