VEGF and therapeutic opportunities in cardiovascular diseases.
In the past ten years, alternative revascularization strategies have come from bench to bedside focusing on the growth of new vessels to replace the old. Hypoxia and vascular endothelial growth factor may induce capillary growth; however, atherosclerosis affects large conductance vessels, which can only be replaced by functional collateral arteries.
Schaper
W
W
Department of Experimental Cardiology, Max-Planck-Institute for Physiological and Clinical Research, Bad Nauheim, Germany.
Buschmann
I
I
D002318:Cardiovascular Diseases / Q000473:pathology / Q000628:therapy*; D016228:Endothelial Growth Factors / Q000502:physiology*; D006801:Humans; D008222:Lymphokines / Q000502:physiology*; D009369:Neoplasms / Q000098:blood supply; D009389:Neovascularization, Pathologic; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
D016228:Endothelial Growth Factors; D008222:Lymphokines; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors