title: Evidence that expression of the Vibrio vulnificus hemolysin gene is dependent on cyclic AMP and cyclic AMP receptor protein.
abstract: Glucose repressed hemolysin production in Vibrio vulnificus. Promoter activity of the hemolysin gene, vvh, assessed with a vvh-luxCDABE transcriptional fusion, required cyclic AMP (cAMP) and cAMP receptor protein (CRP) in Escherichia coli. Hemolysin production in V. vulnificus increased after the addition of cAMP and was undetectable in a putative crp mutant, suggesting that vvh is also regulated by cAMP-CRP in V. vulnificus.
authors.affiliation: Department of Food Science and Technology, Institute of Biotechnology, Chonnam National University, Kwang-Ju, 500-757.
authors.forename: Y B
authors.initials: YB
authors.lastname: Bang
authors.forename: S E
authors.initials: SE
authors.lastname: Lee
authors.forename: J H
authors.initials: JH
authors.lastname: Rhee
authors.forename: S H
authors.initials: SH
authors.lastname: Choi
mesh_terms: D000818:Animals; D000242:Cyclic AMP / Q000502:physiology*; D002373:Cyclic AMP Receptor Protein / Q000502:physiology*; D015964:Gene Expression Regulation, Bacterial; D005947:Glucose / Q000378:metabolism; D006460:Hemolysin Proteins / Q000235:genetics*; D006801:Humans; D011401:Promoter Regions, Genetic; D012756:Sheep; D014733:Vibrio / Q000235:genetics* / Q000378:metabolism
chemical_list: D002373:Cyclic AMP Receptor Protein; D006460:Hemolysin Proteins; D000242:Cyclic AMP; D005947:Glucose