title: Epstein-Barr virus-induced posttransplant lymphoproliferative disorders. ASTS/ASTP EBV-PTLD Task Force and The Mayo Clinic Organized International Consensus Development Meeting.
abstract: Epstein-Barr virus-induced posttransplant lymphoproliferative disease (EBV-PTLD) continues to be a major complication after solid organ transplantation in high-risk patients. Despite the identification of risk factors that predispose patients to develop EBV-PTLD, limitations in our knowledge of its pathogenesis, variable criteria for establishing the diagnosis, and lack of randomized studies addressing the prevention and treatment of EBV-PTLD hamper the optimal management of this transplant complication. This review summarizes the current knowledge of EBV-PTLD and, as a result of two separate international meetings on this topic, and provides recommendations for future areas of study.
authors.affiliation: Department of Immunology, Mayo Transplant Center, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors.forename: C V
authors.initials: CV
authors.lastname: Paya
authors.forename: J J
authors.initials: JJ
authors.lastname: Fung
authors.forename: M A
authors.initials: MA
authors.lastname: Nalesnik
authors.forename: E
authors.initials: E
authors.lastname: Kieff
authors.forename: M
authors.initials: M
authors.lastname: Green
authors.forename: G
authors.initials: G
authors.lastname: Gores
authors.forename: T M
authors.initials: TM
authors.lastname: Habermann
authors.forename: P H
authors.initials: PH
authors.lastname: Wiesner
authors.forename: J L
authors.initials: JL
authors.lastname: Swinnen
authors.forename: E S
authors.initials: ES
authors.lastname: Woodle
authors.forename: J S
authors.initials: JS
authors.lastname: Bromberg
mesh_terms: D020031:Epstein-Barr Virus Infections / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D004854:Herpesvirus 4, Human; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D016377:Organ Transplantation / Q000009:adverse effects*; D011183:Postoperative Complications / Q000821:virology*