[An experimental study of the patterns in the development of an inflammatory process in the mandibular bone tissue caused by exposure to anaerobic microflora].
Inflammatory process in mandibular bone was induced in 39 outbred rats by a pure culture of Bacteroides fragilis and by an associative culture of B. fragilis and Staphylococcus aureus. Anaerobic microflora notably aggravated the course of inflammation. In contrast to inflammation in other parts of the skeleton, inflammation of the jaws involves a high risk of infection of the oral cavity by pathogenic microflora. A variety of microorganisms is isolated from the focus: from gram-positive staphylococci to gram-negative enterobacteria, which fact should be borne in mind when planning antibiotic therapy. Combined use of antibiotics active towards the entire spectrum of agents detected in this study is the most effective.
Pankratov
A S
AS
Korshunov
V M
VM
Kafarskaia
L I
LI
Dreval'
A A
AA
D000818:Animals; D001442:Bacteroides Infections / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D001441:Bacteroides fragilis / Q000302:isolation & purification; D004195:Disease Models, Animal; D008334:Mandible / Q000382:microbiology / Q000473:pathology; D008336:Mandibular Diseases / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D008854:Microscopy, Electron; D010000:Osteitis / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D051381:Rats; D013203:Staphylococcal Infections / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D013211:Staphylococcus aureus / Q000302:isolation & purification; D013997:Time Factors
Eksperimental'noe issledovanie zakonomernosteĭ razvitiia vospalitel'nogo protsessa v kostnoĭ tkani nizhneĭ cheliusti, obuslovlennogo vozdeĭstviem anaérobnoĭ mikroflory.