Malignant rhabdoid tumor beside benign skin mesenchymal neoplasm with myofibromatous features.
Only a few reports of primary cutaneous rhabdoid tumors have been published. We describe the case of a 3-month-old female patient who developed a rhabdoid type cutaneous sarcomatoid neoplasm in her upper back, close to a benign myofibromatous proliferation of infancy. The lesion was studied both by light microscopy and immunohistochemically. Flow cytometry was performed showing a DNA diploid profile of the malignant tumor. The pathological findings suggest a mesenchymal origin (hemangiopericytic or myofibroblastic type) for both tumors. The patient was surgically treated, but she died nine months later.
García-Bustínduy
M
M
Department of Dermatology, Hospital Universitario de Canarias, University of La Laguna, Tenerife, Spain. mgarciab@ull.es
Alvarez-Arguelles
H
H
Guimerá
F
F
García-Castro
C
C
Sánchez-González
R
R
Hernández
N
N
Diaz-Flores
L
L
García-Montelongo
R
R
D014408:Biomarkers, Tumor / Q000032:analysis; D002469:Cell Separation; D004273:DNA, Neoplasm / Q000032:analysis; D017809:Fatal Outcome; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D008637:Mesenchymoma / Q000737:chemistry / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D011003:Ploidies; D018335:Rhabdoid Tumor / Q000737:chemistry / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000737:chemistry / Q000235:genetics / Q000473:pathology* / Q000601:surgery
D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm