title: Membrane chromatography: preparation and applications to protein separation.
abstract: As a result of the convective flow of solutes through porous membranes, membrane chromatography has a higher capture efficiency and a higher productivity than column chromatography and shows most promising industrial applications for the recovery, isolation, and purification of proteins and enzymes. This paper presents a comprehensive review of the methods for preparation of adsorptive membranes (such as surface modification, in situ copolymerization, direct formation from hydrophilic materials, and functionalized particulate-entrapped membranes) and deals particularly with novel macroporous chitin and chitosan membranes for protein separations developed by the authors.
authors.affiliation: Department of Chemical Engineering, State University of New York at Buffalo, Amherst, New York 14260, USA.
authors.forename: X
authors.initials: X
authors.lastname: Zeng
authors.forename: E
authors.initials: E
authors.lastname: Ruckenstein
mesh_terms: D002240:Carbohydrate Sequence; D002482:Cellulose / Q000737:chemistry; D002686:Chitin / Q000031:analogs & derivatives / Q000737:chemistry; D048271:Chitosan; D002845:Chromatography / Q000379:methods*; D004798:Enzymes / Q000302:isolation & purification*; D008567:Membranes, Artificial; D008969:Molecular Sequence Data; D011506:Proteins / Q000302:isolation & purification*
chemical_list: D004798:Enzymes; D008567:Membranes, Artificial; D011506:Proteins; D002686:Chitin; D002482:Cellulose; D048271:Chitosan