title: [Acute Corynebacterium diphtheriae aortic endocarditis with negative blood cultures].
abstract: Acute endocarditis with negative blood culture is a challenge requiring close cooperation between several specialists.
  
  
  METHODS
  A 15-year-old boy presented with an acute aortic endocarditis due to Corynebacterium diphtheriae. Blood cultures were negative due to an empiric anti-infective therapy. Valvular replacement with a mechanical prosthesis failed to cure the sepsis, which resolved after a cryopreserved allograft implantation.
  
  
  CONCLUSIONS
  This case underlines the efficiency of the highly specialized bacteriological centers and the advantages of using a cryopreserved allograft during the septic state.
authors.affiliation: Institut cardiovasculaire Paris-Sud, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Durandy
authors.forename: S
authors.initials: S
authors.lastname: Hulin
mesh_terms: D000293:Adolescent; D001018:Aortic Diseases / Q000382:microbiology* / Q000601:surgery; D003353:Corynebacterium diphtheriae / Q000302:isolation & purification; D004165:Diphtheria / Q000150:complications* / Q000175:diagnosis; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D005188:False Negative Reactions; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D018805:Sepsis / Q000209:etiology
vernacular_title: Endocardite aortique aiguë à Corynebacterium diphteriae à hémoculture négative.