Successful treatment with nitazoxanide of Enterocytozoon bieneusi microsporidiosis in a patient with AIDS.
A patient with AIDS and chronic diarrhea caused by Enterocytozoon bieneusi was successfully treated with nitazoxanide, producing a complete clinical and parasitological response, while off of antiviral therapy. This suggests that nitazoxanide may be effective in treating microsporidiosis caused by E. bieneusi, a disease for which there is no established treatment.
Bicart-Sée
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Department of Infectious and Tropical Diseases, Purpan Hospital, Toulouse, France. bicart@club-internet.fr
Massip
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P
Linas
M D
MD
Datry
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A
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D003967:Diarrhea / Q000188:drug therapy*; D006801:Humans; D008297:Male; D016816:Microsporida; D016881:Microsporidiosis / Q000188:drug therapy*; D009574:Nitro Compounds; D013844:Thiazoles / Q000627:therapeutic use*
D000981:Antiprotozoal Agents; D009574:Nitro Compounds; D013844:Thiazoles; C041747:nitazoxanide