title: [Histological changes related to scleral buckling for treatment of retinal detachment].
abstract: Treatment of retinal detachment frequently uses biocompatible materials to obtain scleral buckling. These materials are not devoid of consequences on surrounding tissues. In 3 eyes enucleated for failure of surgical treatment using scleral buckling materials, the changes prompted by episcleral implants could be observed. The sclera underwent both an inversion of its curvature and a reduction of its thickness under the material, as well as an encapsulation of the material was observed. While a silicone sponge was used in part to encircle one of these eyes, its capsular inner surface was regular and smooth. In contrast, hydrogel implants used in the three eyes showed a peripheral fragmentation prompting in two of them a typical foreign body giant cell granulomatous reaction. Changes in scleral curvature and scleral thinning were observed reflecting the consequences of the buckling procedure. The capsule formation occurred as it does for any nonabsorbable matérial implanted in tissues. Degradation and fragmentation of the hydrogel material suscitated a granuloma in response to fragments. These hydrogel specific changes should be recognized on microscopic examination of slides of either capsule or eyes previously in contact with this implanted material. They attested of the instability of hydrogel after implantation.
authors.affiliation: Laboratoire d'Ophtalmologie, Hôtel-Dieu, Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: D'Hermies
authors.forename: J F
authors.initials: JF
authors.lastname: Korobelnik
authors.forename: A
authors.initials: A
authors.lastname: Meyer
authors.forename: X
authors.initials: X
authors.lastname: Morel
authors.forename: F
authors.initials: F
authors.lastname: Béhar-Cohen
authors.forename: S
authors.initials: S
authors.lastname: Bertin
authors.forename: N
authors.initials: N
authors.lastname: Chérif
authors.forename: D
authors.initials: D
authors.lastname: Chauvaud
authors.forename: G
authors.initials: G
authors.lastname: Renard
authors.forename: J
authors.initials: J
authors.lastname: Audouin
authors.forename: J
authors.initials: J
authors.lastname: Diebold
authors.forename: A
authors.initials: A
authors.lastname: Duprez
mesh_terms: D000368:Aged; D002648:Child; D015353:Eye Enucleation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants; D012163:Retinal Detachment / Q000601:surgery*; D012590:Sclera / Q000473:pathology*; D012591:Scleral Buckling / Q000009:adverse effects*
vernacular_title: Altérations anatomopathologiques liées au traitement par cerclage des globes oculaires atteints de décollement de rétine.