[Ventricular tachycardia after erythromycin administration in a newborn with congenital AV-block].
This report is on a newborn with congenital complete av-block due to a maternal collagenosis. The intravenous application of erythromycin produced premature ventricular beats and non sustained ventricular tachycardias by prolongation of the QT interval. After discontinuation of the erythromycin application, the QT-interval normalised.


CONCLUSIONS
In atrioventricular conduction disorders with severe bradycardia and prolongation of the QT interval, the application of erythromycin--if unavoidable--should be managed by slow intravenous infusion and with permanent ECG monitoring.
Brixius
B
B
Abteilung für Pädiatrische Kardiologie, Universitätsklinik für Kinder- u. Jugendmedizin, Homburg/Saar.
Lindinger
A
A
Baghai
A
A
Limbach
H G
HG
Hoffmann
W
W
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004562:Electrocardiography; D004917:Erythromycin / Q000008:administration & dosage / Q000009:adverse effects*; D006327:Heart Block / Q000150:complications* / Q000151:congenital* / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D007275:Injections, Intravenous; D008297:Male; D018805:Sepsis / Q000150:complications / Q000188:drug therapy*; D017180:Tachycardia, Ventricular / Q000139:chemically induced* / Q000503:physiopathology; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D004917:Erythromycin
Ventrikuläre Tachykardie nach Erythromycin-Gabe bei einem Neugeborenen mit angeborenem AV-Block.