Iron and activated oxygen species in biology: the basic chemistry.
This paper briefly presents a critical review concerning the chemical reactions involved when superoxide or hydrogen peroxide meet iron complexes. The data commented on are required for a correct interpretation of the chemical processes which play a paramount role in the biological activation of dioxygen and arise in normal metabolism as well as in pathological processes.
Pierre
J L
JL
Laboratoire de Chimie Biomimétique, LEDSS, UMR CNRS 5616, Université J. Fourier, Grenoble, France. Jean-Louis.Pierre@ujf-grenoble.fr
Fontecave
M
M
D007501:Iron / Q000737:chemistry* / Q000378:metabolism*; D010084:Oxidation-Reduction; D017382:Reactive Oxygen Species / Q000378:metabolism*
D017382:Reactive Oxygen Species; D007501:Iron