title: Optical coherence tomography images of spontaneous macular hole closure.
abstract: OBJECTIVE
  To investigate optical coherence tomography images of spontaneous macular hole closure.
  
  
  METHODS
  Case report. In a 60-year-old woman with full-thickness macular hole, posterior vitreous detachment, and previous branch retinal vein occlusion, we observed the entire course of spontaneous macular hole closure by use of optical coherence tomography.
  
  
  RESULTS
  Spontaneous macular hole closure began as the inward protrusion of the tissue around the margin of the macular hole. The protruding tissue then connected to bridge the macular hole, which mimicked a foveal retinal detachment. The bridged tissue gradually thickened, and the foveal detachment and perifoveal cysts resolved. The fovea eventually regained its normal configuration.
  
  
  CONCLUSIONS
  The bridging of the protruding retinal tissue over the macular hole plays a key role in spontaneous macular hole closure.
authors.affiliation: Department of Ophthalmology, Gunma University School of Medicine, Maebashi, Japan. hidetot@akagi.sb.gunma-u.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
authors.forename: S
authors.initials: S
authors.lastname: Kishi
mesh_terms: D003560:Cysts / Q000150:complications / Q000473:pathology; D005260:Female; D005584:Fovea Centralis / Q000473:pathology; D005654:Fundus Oculi; D006801:Humans; D008875:Middle Aged; D055095:Optics and Photonics; D012075:Remission, Spontaneous; D012164:Retinal Diseases / Q000150:complications / Q000473:pathology; D012167:Retinal Perforations / Q000150:complications / Q000473:pathology* / Q000503:physiopathology*; D014054:Tomography