Allergic contact dermatitis to polyethylene glycol and nitrofurazone.
We report a case of worsening dermatitis after the application of an antibiotic ointment (Furacin) containing furazone and polyethylene glycol. Patch tests to nickel sulfate, potassium dischromate, chloride cobalt, Furacin, nitrofurazone 1% petrolatum, polyethylene glycol mix 4% petrolatum, polyethylene glycol (PEG) 300 4% petrolatum, and PEG 400 as is (ai) were positive. The use of topical agents containing nitrofurazone or polyethylene glycol on damaged skin may predispose to contact allergy. We discuss the sensitizing properties of nitrofurazone and polyethylene glycol.
Guijarro
S C
SC
Department of Dermatology, Hospital Universitario de la Princesa, Madrid, Spain.
Sánchez-Pérez
J
J
García-Díez
A
A
D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000009:adverse effects*; D002056:Burns / Q000188:drug therapy; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007868:Leg Dermatoses / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D009583:Nitrofurazone / Q000008:administration & dosage / Q000009:adverse effects*; D010328:Patch Tests; D011092:Polyethylene Glycols / Q000008:administration & dosage / Q000009:adverse effects*
D000891:Anti-Infective Agents, Local; D011092:Polyethylene Glycols; D009583:Nitrofurazone