title: Promiscuous origin of a chimeric sequence in the Escherichia coli O157:H7 genome.
abstract: A novel sequence of 2.9 kb in the intergenic region between the mutS and rpoS genes of Escherichia coli O157:H7 and closely related strains replaces a sequence of 6.1 kb in E. coli K-12 strains. At the same locus in Shigella dysenteriae type 1, a sequence identical to that in O157:H7 is bounded by the IS1 insertion sequence element. Extensive polymorphism in the mutS-rpoS chromosomal region is indicative of horizontal transfer events.
authors.affiliation: Molecular Biology Branch, Center for Food Safety and Applied Nutrition, Food and Drug Administration, Washington, D.C. 20204, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: LeClerc
authors.forename: B
authors.initials: B
authors.lastname: Li
authors.forename: W L
authors.initials: WL
authors.lastname: Payne
authors.forename: T A
authors.initials: TA
authors.lastname: Cebula
mesh_terms: D000251:Adenosine Triphosphatases; D001426:Bacterial Proteins / Q000235:genetics; D001483:Base Sequence; D002874:Chromosome Mapping; D004268:DNA-Binding Proteins; D019453:Escherichia coli O157 / Q000235:genetics*; D029968:Escherichia coli Proteins; D016680:Genome, Bacterial; D008969:Molecular Sequence Data; D051719:MutS DNA Mismatch-Binding Protein; D009690:Nucleic Acid Conformation; D011993:Recombinant Fusion Proteins / Q000235:genetics; D012808:Sigma Factor / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; D011993:Recombinant Fusion Proteins; D012808:Sigma Factor; C069567:sigma factor KatF protein, Bacteria; D000251:Adenosine Triphosphatases; D051719:MutS DNA Mismatch-Binding Protein; C497175:MutS protein, E coli