title: Cytologic diagnosis of vaginal metastasis from renal cell carcinoma. A case report.
abstract: BACKGROUND
  Metastasis of renal cell carcinoma to the vagina is rare, although it may be the first evidence of the existence of the primary tumor.
  
  
  METHODS
  A metastatic deposit of renal cell carcinoma in the vagina was diagnosed by cytology as clear cell adenocarcinoma, which was confirmed by biopsy. Radiographic and ultrasound examinations confirmed the renal site of origin, which was corroborated by immunohistochemistry of the biopsy specimen.
  
  
  CONCLUSIONS
  When a cytologic diagnosis of vaginal clear cell adenocarcinoma is made, metastasis of renal cell carcinoma should be considered in the differential diagnosis.
authors.affiliation: Department of Gynecology, Obstetrics and Human Reproduction, Federal University of Bahia, Brazil.
authors.forename: C
authors.initials: C
authors.lastname: Queiroz
authors.forename: C E
authors.initials: CE
authors.lastname: Bacchi
authors.forename: C
authors.initials: C
authors.lastname: Oliveira
authors.forename: M
authors.initials: M
authors.lastname: Carvalho
authors.forename: D R
authors.initials: DR
authors.lastname: Santos
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000473:pathology*; D001706:Biopsy; D002292:Carcinoma, Renal Cell / Q000175:diagnosis* / Q000556:secondary; D003581:Cytodiagnosis / Q000379:methods*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000473:pathology*; D008875:Middle Aged; D014625:Vaginal Neoplasms / Q000175:diagnosis* / Q000556:secondary