title: MR findings in a patient with Kernicterus.
abstract: We report on a 2.5-year-old boy with severe mental retardation, choreoathetosis, dystonia, muscle rigidity, opisthotonus and severe hearing impairment. He had history of severe hyperbilirubinaemia immediately after birth presumably due to ABO incompatibility. The history and the clinical picture suggested the diagnosis of Kernicterus. The MR imaging examination upon admission revealed bilateral signal intensity increase in the globus pallidum on T2-weighted sequences. Additionally, our patient showed signal intensity changes within the subthalamic nuclei, which is known to be another characteristic area of bilirubin deposition in Kernicterus.
authors.affiliation: Department of Diagnostic Radiology, Klinikum Grosshadern, Ludwig-Maximilians University, Marchioninistrasse 15, D-81377 Munich, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Steinborn
authors.forename: K C
authors.initials: KC
authors.lastname: Seelos
authors.forename: A
authors.initials: A
authors.lastname: Heuck
authors.forename: H
authors.initials: H
authors.lastname: von Voss
authors.forename: M
authors.initials: M
authors.lastname: Reiser
mesh_terms: D000015:Abnormalities, Multiple; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005911:Gliosis / Q000175:diagnosis / Q000209:etiology; D005917:Globus Pallidus / Q000473:pathology*; D006801:Humans; D007647:Kernicterus / Q000150:complications / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D020531:Subthalamic Nucleus / Q000473:pathology*