title: Accuracy of T2-weighted fast spin-echo MR imaging with fat saturation in detecting cartilage defects in the knee: comparison with arthroscopy in 130 patients.
abstract: OBJECTIVE
  The purpose of this study was to assess the accuracy of routine T2-weighted MR imaging in detecting and grading articular cartilage lesions in the knee compared with arthroscopy.
  
  
  METHODS
  We examined 130 consecutive patients who underwent MR imaging and arthroscopy of the knee for suspected internal derangement. MR imaging consisted of axial and coronal T2-weighted fast spin-echo sequences with fat saturation and sagittal T2-weighted spin-echo sequences. Each single plane was evaluated and graded for the presence and appearance of articular cartilage defects using a standard arthroscopic grading scheme adapted to MR imaging.
  
  
  RESULTS
  Of the 86 arthroscopically proven abnormalities, 81 were detected on MR imaging. Sensitivity of the T2-weighted fast spin-echo sequence with fat saturation was 61% for the coronal plane alone and 59% for the axial plane alone. Specificity for each plane was 99%. Sensitivity for the sagittal T2-weighted spin-echo sequence was 40%, and specificity was 100%. Sensitivity of the combination of axial and coronal T2-weighted fast spin-echo sequences with fat saturation and sagittal T2-weighted spin-echo sequence compared with arthroscopy for revealing cartilage lesions was 94%, specificity was 99%, and accuracy was 98%. Sensitivity of coronal and axial T2-weighted fast spin-echo sequences with fat saturation was 93%, and specificity was 99%. Fifty-five lesions (64%) were identically graded on MR imaging and arthroscopy. Seventy-eight lesions (90%) were within one grade using MR imaging and arthroscopy, and 84 lesions (97%) were within two grades using MR imaging and arthroscopy.
  
  
  CONCLUSIONS
  T2-weighted fast spin-echo MR imaging with fat saturation is an accurate and fast technique for detecting and grading articular cartilage defects in the knee. The combination of the axial and coronal planes offers sufficient coverage of articular surfaces to provide a high sensitivity and specificity for chondral defects.
authors.affiliation: Department of Radiology, University of California, San Francisco 94143-0628, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Bredella
authors.forename: P F
authors.initials: PF
authors.lastname: Tirman
authors.forename: C G
authors.initials: CG
authors.lastname: Peterfy
authors.forename: M
authors.initials: M
authors.lastname: Zarlingo
authors.forename: J F
authors.initials: JF
authors.lastname: Feller
authors.forename: F W
authors.initials: FW
authors.lastname: Bost
authors.forename: J P
authors.initials: JP
authors.lastname: Belzer
authors.forename: T K
authors.initials: TK
authors.lastname: Wischer
authors.forename: H K
authors.initials: HK
authors.lastname: Genant
mesh_terms: D000328:Adult; D000368:Aged; D001182:Arthroscopy; D002357:Cartilage Diseases / Q000175:diagnosis; D002358:Cartilage, Articular / Q000473:pathology*; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000175:diagnosis; D007719:Knee Joint / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012680:Sensitivity and Specificity