title: Solitary bone plasmacytoma: management of isolated local relapse following radiotherapy.
abstract: Radiotherapy is the prime treatment modality for solitary plasmacytomas of bone (SPB). Although local control rates are excellent, progression to multiple myeloma is frequent, albeit with varying latency. Local failure in the absence of dissemination is rare and thus management is poorly documented. We discuss such a patient who presented 3 years after local radiation for a pelvic SPB and review the relevant literature. Radiation doses, portals employed and prognostic factors that may predict progression to myeloma are discussed. This report shows that an isolated recurrence of SPB in a previously irradiated field was successfully treated with orthopaedic surgery. This resulted in good pain relief and mobility for the patient, who remains free of disease 6 months after operation.
authors.affiliation: Mount Vernon Centre for Cancer Treatment, Northwood, UK.
authors.forename: C R
authors.initials: CR
authors.lastname: Lewanski
authors.forename: T
authors.initials: T
authors.lastname: Bates
authors.forename: J
authors.initials: J
authors.lastname: Bowen
authors.forename: R F
authors.initials: RF
authors.lastname: Ashford
mesh_terms: D000077:Acetabulum / Q000000981:diagnostic imaging / Q000601:surgery*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery*; D018450:Disease Progression; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000601:surgery*; D010954:Plasmacytoma / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery*; D011630:Pubic Bone / Q000000981:diagnostic imaging / Q000601:surgery*; D011859:Radiography