title: Acute vision loss in children with autosomal recessive polycystic kidney disease.
abstract: Patients with autosomal recessive polycystic kidney disease (ARPKD) often present with renal insufficiency and hypertension. We present two children with ARPKD and end-stage renal disease who developed anterior ischemic optic neuropathy and vision loss. Anterior ischemic optic neuropathy occurs rarely in children and has never been reported in children with ARPKD or end-stage renal disease. Both of our patients were chronically hypotensive and anemic, which are known risk factors for ischemic optic neuropathy.
authors.affiliation: Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 75235-9063, USA.
authors.forename: C M
authors.initials: CM
authors.lastname: Bates
authors.forename: M
authors.initials: M
authors.lastname: Baum
authors.forename: M
authors.initials: M
authors.lastname: Hunchik
authors.forename: A
authors.initials: A
authors.lastname: Quan
mesh_terms: D000740:Anemia / Q000150:complications; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007022:Hypotension / Q000150:complications; D007223:Infant; D008297:Male; D018917:Optic Neuropathy, Ischemic / Q000150:complications*; D017044:Polycystic Kidney, Autosomal Recessive / Q000150:complications*; D012307:Risk Factors; D014786:Vision Disorders / Q000209:etiology