title: Laser surgery for allergic and hypertrophic rhinitis.
abstract: Laser surgery, which is one type of surgical treatment for allergic and hypertrophic rhinitis, was investigated basically and clinically. The basic investigation showed morphological changes in the nasal mucosa before and after laser surgery. Before laser surgery, hyperplasia of the mucous epithelium, thickening of the basement membrane, edema of the lamina propria mucosa, eosinophilic infiltration, and enlargement of the nasal glands were noted. After laser surgery, the nasal mucosa was covered with 1) epithelium that was squamatized or cuboidal and/or 2) columnar epithelium that was stratified. Granulation-like tissue or cicatricial tissue was found in the lamina propria mucosa. Clinically, we performed laser surgery in 204 cases. Regarding the short-term results, laser surgery was effective in 87%. In the long term, the short-term results persisted in 81% of cases treated for sneezing, 78% for nasal discharge, and 76% for nasal obstruction. From these results, we concluded that laser surgery was a useful surgical treatment for allergic and hypertrophic rhinitis.
authors.affiliation: Department of Otolaryngology, International University for Health and Welfare, Sanno Hospital, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Inouye
authors.forename: T
authors.initials: T
authors.lastname: Tanabe
authors.forename: M
authors.initials: M
authors.lastname: Nakanoboh
authors.forename: M
authors.initials: M
authors.lastname: Ogura
mesh_terms: D000293:Adolescent; D000328:Adult; D000403:Airway Resistance; D002648:Child; D005260:Female; D006801:Humans; D006984:Hypertrophy; D053685:Laser Therapy; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D009297:Nasal Mucosa / Q000473:pathology / Q000648:ultrastructure; D015508:Nasal Obstruction / Q000601:surgery; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods; D012220:Rhinitis / Q000473:pathology / Q000601:surgery*; D012221:Rhinitis, Allergic, Perennial / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome