title: [Towards a reliable prognosis for multiple sclerosis].
abstract: Although the general course of multiple sclerosis is well known from natural history studies, the determination of a detailed prognosis in a given individual is almost an insurmountable task. Cerebral magnetic resonance imaging is the best predictor of conversion to definite multiple sclerosis after a first demyelinating event. The main factors indicative of long-term bad prognosis are: onset after the age of 40, initial pyramidal or cerebellar signs, high relapse rate during the first two years, and onset of the progressive phase. Altogether, up to 20% of patients have a benign course.
authors.affiliation: Service de neurologie Hôpital Tenon, Paris.
authors.forename: O
authors.initials: O
authors.lastname: Heinzlef
authors.forename: E
authors.initials: E
authors.lastname: Roullet
mesh_terms: D017668:Age of Onset; D002540:Cerebral Cortex / Q000473:pathology; D018450:Disease Progression; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011379:Prognosis
vernacular_title: Vers un pronostic fiable de la sclérose en plaques.