[Acute cardiotoxicity from 5-fluorouracil: un underestimated toxicity].
The most common toxicity in clinical trials with 5-FU, in mono or polychemotherapy, is stomatitis, diarrhea, hand-foot syndrome. In this case report, the 5-fluorouracil (5-FU) cardiotoxicity, an uncommon 5-FU-related toxicity, has been investigated. Cardiotoxicity reports are uncommon because the problem is not well known. This study is also a review of the recent literature and it recommend to take care in prescribing chemotherapy to patients with heart disease history.
Bertolini
A
A
Ospedale di Sondrio.
Fiumanò
M
M
Muffatti
A
A
Pedroncelli
S
S
Doria
A
A
Codazzi
G
G
Giustiniani
S
S
Scarinci
A
A
Redaelli
G
G
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D004562:Electrocardiography; D005472:Fluorouracil / Q000009:adverse effects*; D006321:Heart / Q000187:drug effects*; D006331:Heart Diseases / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000601:surgery*; D011184:Postoperative Period
D005472:Fluorouracil
Cardiotossicità acuta da 5-fluorouracile: una tossicità sottovalutata.