Sequence of the non-structural protein gene encoded by RNA1 of striped jack nervous necrosis virus.
Striped jack nervous necrosis virus (SJNNV), the causative agent of viral nervous necrosis in marine fish, is a member of the family Nodaviridae whose genome consists of two positive-sense RNA molecules encapsidated in a single virion. In this study, the nucleotide sequence of SJNNV RNA1 was determined. The SJNNV RNA1 was 3081 bases long and contained a single ORF encoding 983 aa of approximately 110 kDa. The sequence identities between RNA1 of SJNNV and RNA1 of insect nodaviruses were 28% at the nucleotide and amino acid levels, although the conserved motifs for the RNA-dependent RNA polymerase were located at almost the same positions in the amino acid sequences. The present study, together with our previous work on SJNNV RNA2, suggests that a new genus, Piscinodavirus, should be created in the family Nodaviridae.
Nagai
Takahiro
T
Faculty of Applied Biological Science, Hiroshima University, Higashi-hiroshima 739-8528, Japan1.
Nishizawa
Toyohiko
T
Faculty of Applied Biological Science, Hiroshima University, Higashi-hiroshima 739-8528, Japan1.
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D005393:Fish Diseases / Q000821:virology*; D005399:Fishes; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D012328:RNA Viruses / Q000145:classification / Q000235:genetics*; D012367:RNA, Viral / Q000737:chemistry*; D017361:Viral Nonstructural Proteins / Q000235:genetics*
D012367:RNA, Viral; D017361:Viral Nonstructural Proteins