Methodological pitfalls in bioequivalence studies: sample size, between-subject and within-subject variability, single or multiple dose studies and metabolite determination.
Frias
J
J
Department of Pharmacology and Therapeutics, Faculty of Medicine, Universidad Autónoma de Madrid, Spain.
Guerra
P
P
Soto
A
A
García
O
O
Carcas
A J
AJ
D012106:Research / Q000458:organization & administration*; D012107:Research Design; D018401:Sample Size; D013810:Therapeutic Equivalency