Humoral immune responses to multiple antigens of Mycobacterium tuberculosis in tuberculosis patients co-infected with the human immunodeficiency virus.
A panel of ten protein antigens of Mycobacterium tuberculosis was used to evaluate serum antibody responses to tuberculosis in patients co-infected with the human immunodeficiency virus (HIV) and in HIV-infected control individuals without tuberculosis. Most (70%) of the tuberculosis patients had serum reactivity to at least one antigen and maintained the diverse antibody repertoire previously observed in HIV-negative tuberculosis patients.
Colangeli
R
R
Public Health Research Institute, New York, New York 10016, USA.
Antinori
A
A
Cingolani
A
A
Ortona
L
L
Lyashchenko
K
K
Fadda
G
G
Gennaro
M L
ML
D000917:Antibody Formation; D000942:Antigens, Bacterial / Q000276:immunology*; D015897:Comorbidity; D004797:Enzyme-Linked Immunosorbent Assay; D005240:Feasibility Studies; D015658:HIV Infections / Q000453:epidemiology*; D006801:Humans; D011994:Recombinant Proteins; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology* / Q000276:immunology*
D000942:Antigens, Bacterial; D011994:Recombinant Proteins