Local corticosteroid treatment of caustic injuries of the esophagus. A preliminary report.
So far, no therapy has been shown to reduce the incidence of strictures in the esophagus after ingestion of caustic agents. Two patients with pronounced caustic ingestion injuries were treated locally with solutions of corticosteroids normally used for inhalation therapy in lung diseases. Serious strictures did not appear, and their swallowing returned to normal. Further studies are needed.
Gunnarsson
M
M
Department of Otorhinolaryngology, Central Hospital, Karlstad, Sweden.
D000287:Administration, Topical; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001507:Beclomethasone / Q000627:therapeutic use; D019819:Budesonide / Q000627:therapeutic use; D002057:Burns, Chemical / Q000188:drug therapy*; D002424:Caustics / Q000009:adverse effects*; D003902:Detergents / Q000009:adverse effects; D004940:Esophageal Stenosis / Q000139:chemically induced / Q000517:prevention & control*; D004945:Esophagoscopy; D004947:Esophagus / Q000187:drug effects* / Q000293:injuries; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D008875:Middle Aged; D012972:Sodium Hydroxide / Q000009:adverse effects; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D002424:Caustics; D003902:Detergents; D005938:Glucocorticoids; D019819:Budesonide; D012972:Sodium Hydroxide; D001507:Beclomethasone