[Environment, genetics and immunology in multiple sclerosis].
The cause of multiple sclerosis remains unknown. Epidemiological studies indicate that it is a multi-factorial disease. The environmental factors are still unknown. No virus has been yet demonstrated to play a role in multiple sclerosis. The role of HLA in the genetic susceptibility has been known since the seventies; the detailed analysis is underway. Immunological factors playing a role in the course of multiple sclerosis are better known and may serve as basis to new therapeutical approaches.
Liblau
R
R
Laboratoire d'immunologie cellulaire, Université Pierre-et-Marie-Curie Groupe hospitalier La Pitié-La Salpêtrière, Paris.
Fontaine
B
B
D004777:Environment; D020022:Genetic Predisposition to Disease; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D007167:Immunotherapy; D007249:Inflammation / Q000276:immunology; D009103:Multiple Sclerosis / Q000235:genetics / Q000276:immunology / Q000503:physiopathology
D006680:HLA Antigens
Environnement, génétique et immunologie dans la sclérose en plaques.