title: Genetic disorders of hemoglobin.
abstract: The inherited disorders of hemoglobin, the most common monogenic diseases, are now well understood at the molecular and cellular level, knowledge which has led to considerable Improvements in their control and management. Because of their particularly high gene frequencies in sub-Saharan Africa, the Indian subcontinent, and throughout Southeast Asia, the organization of their control and treatment provides a major challenge for the new millennium.
authors.affiliation: Medical Research Council Molecular Haematology Unit, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK.
authors.forename: D J
authors.initials: DJ
authors.lastname: Weatherall
authors.forename: J B
authors.initials: JB
authors.lastname: Clegg
mesh_terms: D005192:Family Health; D005787:Gene Frequency; D006405:Hematology / Q000266:history; D006453:Hemoglobinopathies / Q000235:genetics*; D006454:Hemoglobins / Q000235:genetics*; D006455:Hemoglobins, Abnormal / Q000235:genetics; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans
chemical_list: D006454:Hemoglobins; D006455:Hemoglobins, Abnormal