title: The use of biological glue in aortic surgery.
abstract: The biologic sealants presently available on the market that are used in cardiovascular surgery and particularly during surgery of the aorta are described in this article. Two of these biological sealants, the gelatin-resorcinol-formaldehyde (GRF) glue and two-component fibrin sealant have been in use for two decades. Their respective properties are described beneficial in modifying the natural history of the disease. Certain pharmacological agents that result in improved aortic function have been identified.
authors.affiliation: Service de Chirurgie Cardio-vasculaire, Hôpital Foch-Université René Descartes, Suresnes, France.
authors.forename: J
authors.initials: J
authors.lastname: Bachet
authors.forename: D
authors.initials: D
authors.lastname: Guilmet
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000784:Aortic Dissection / Q000401:mortality / Q000601:surgery*; D001011:Aorta / Q000601:surgery; D017545:Aortic Aneurysm, Thoracic / Q000401:mortality / Q000601:surgery*; D001019:Aortic Rupture / Q000401:mortality / Q000601:surgery*; D001021:Aortic Valve / Q000601:surgery; D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use; D005557:Formaldehyde / Q000627:therapeutic use; D005780:Gelatin / Q000627:therapeutic use; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D012118:Resorcinols / Q000627:therapeutic use; D015996:Survival Rate; D014014:Tissue Adhesives / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D012118:Resorcinols; D014014:Tissue Adhesives; C027813:gelatin-resorcinol-formaldehyde tissue adhesive; D005557:Formaldehyde; D005780:Gelatin