title: [Acute methotrexate toxicity in psoriasis].
abstract: A 71-year-old man with psoriasis developed acute methotrexate toxicity after taking 10 mg daily on his own. A few days after, he showed painful erosions of psoriatic plaques and stomatitis. In addition to those mucocutaneous lesions, the clinical background includes bone marrow and intestinal involvement. The present clinical case underlies the relevance in selecting psoriasis patients regarding methotrexate treatment, following the particular guidelines.
authors.affiliation: Servicio de Dermatología, Hospital de Especialidades, CMN Siglo XXI, IMSS, México, D.F.
authors.forename: A
authors.initials: A
authors.lastname: Arévalo-López
mesh_terms: D000368:Aged; D002908:Chronic Disease; D003879:Dermatologic Agents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000009:adverse effects*; D011041:Poisoning / Q000175:diagnosis / Q000209:etiology; D011565:Psoriasis / Q000150:complications* / Q000188:drug therapy; D012646:Self Administration / Q000009:adverse effects
chemical_list: D003879:Dermatologic Agents; D008727:Methotrexate
vernacular_title: Toxicidad aguda por metotrexate en psoriasis.