title: Short-lasting primary headaches: focus on trigeminal automatic cephalgias and indomethacin-sensitive headaches.
abstract: Short-lasting primary headache syndromes provides both a diagnostic challenge and considerable therapeutic reward. Primary short-lasting headaches broadly divide themselves into those associated with auto nomic symptoms, trigeminalautonomic cephalgias and those with little autonomic syndromes. The trigeminal-autonomic cephalgias include cluster headache and paroxysmal hemicranias, in which head pain and cranial autonomic symptoms are prominent. Consideration of short- lasting headaches, particularly in the context of the differential diagnosis between cluster headache and paroxysmal hemicrania leads to a consideration of indomethacin-sensitive headaches. There are a group of headaches, such as paroxysmal hemicrania and hemicrana continua , which have a curious and a very robust response to indomethacin. These headaches tend to be referred to neurologists as they are refractory to other treatments and thus are useful to know about.
authors.affiliation: Institute of Neurology National Hospital for Neurology and Neurosurgery, London, UK. peterg@brain.ion.ucl.ac.uk
authors.forename: P J
authors.initials: PJ
authors.lastname: Goadsby
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001341:Autonomic Nervous System / Q000503:physiopathology; D003027:Cluster Headache / Q000188:drug therapy*; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D008881:Migraine Disorders / Q000188:drug therapy*; D013997:Time Factors; D014276:Trigeminal Nerve / Q000503:physiopathology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007213:Indomethacin