title: [Treatment of acute biliary pancreatitis in the aged in the endolaparoscopic era].
abstract: BACKGROUND
  Acute biliary pancreatitis (ABP) still retains high morbidity (15-50%) and mortality (20-35%). Therefore it appears to be crucial to clearly assess the aetiological factors (50% of idiopathic are in fact biliary pancreatitis) and to establish the severity in order to plan the appropriate treatment.
  
  
  METHODS
  In this study we have considered 61 patients divided into 2 groups. Group 1 had 29 ABP patients aging less than 65 years, group 232 patients aging more than 65 years; the diagnosis was made by ultrasound and serological values in 78.5% of cases, while in the remaining 21.5% was only serological. Following Ranson and APACHE II scoring 18 cases (29.5%) were classified as severe [6 (20.6%) in group 1; 12 (37.5%) in group 2: p < 0.01], 43 (70.4%) as mild. All patients with severe ABP had emergency ERCP + ES (within 24-48 hrs) followed by LC (< or = 10 days). Patients with mild ABP had LC within 10 days; in these cases IOC was always done.
  
  
  RESULTS
  In severe cases operative endoscopy cured pancreatic inflammation in 13 cases. Subsequent LC never showed serious morbidity, apart subcutaneous emphysema in one case. In 5 cases laparotomy was required since pancreatic necrosis was present, with 60% mortality. In patients with mild pancreatitis LC was successfully performed in all cases, with 6.9% morbidity. IOC showed choledochal stones in 32.5% of cases, while in severe cases stones in the biliary tree were showed in 88.8% of cases. No significant differences were detected between group 1 and 2.
  
  
  CONCLUSIONS
  In conclusion ABP treatment is always surgical, and almost always with minimally-invasive procedures in severe cases (ERCP + ES with LC < or = 10 days) if surgery is performed within 24-48 hrs as well as in mild cases (LC + IOC) when surgery is done within 10 days, independently from the age of the patients.
authors.affiliation: Dipartimento di Discipline Chirurgiche, Università degli Studi, L'Aquila.
authors.forename: M
authors.initials: M
authors.lastname: Schietroma
authors.forename: R
authors.initials: R
authors.lastname: Lattanzio
authors.forename: A
authors.initials: A
authors.lastname: Risetti
authors.forename: R
authors.initials: R
authors.lastname: Di Placido
authors.forename: F
authors.initials: F
authors.lastname: Carlei
authors.forename: S
authors.initials: S
authors.lastname: Leardi
authors.forename: S
authors.initials: S
authors.lastname: Mattucci
authors.forename: N
authors.initials: N
authors.lastname: Bellucci
authors.forename: M A
authors.initials: MA
authors.lastname: Pistoia
authors.forename: M
authors.initials: M
authors.lastname: Simi
mesh_terms: D018806:APACHE; D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002760:Cholangiopancreatography, Endoscopic Retrograde; D017081:Cholecystectomy, Laparoscopic; D002769:Cholelithiasis / Q000150:complications / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*
vernacular_title: Il trattamento della pancreatite acuta biliare nell'anziano nell'era endolaparoscopica.