Escherichia coli resistance to chlorine and glutathione synthesis in response to oxygenation and starvation.
Reduced glutathione (GSH) levels and resistance to chlorine were measured for two isogenic Escherichia coli strains stressed by oxygenation and/or starvation. The E. coli mutant deficient in GSH was not more sensitive to the oxidant than its parent strain when the bacteria were cultured with a low oxygenation rate. Starvation or oxygenation increased the resistance of the parent strain to chlorine, while the resistance of the deficient strain remained unchanged.
Saby
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LCPE-LSE, UMR Université CNRS 7564, France.
Leroy
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Block
J C
JC
D000332:Aerobiosis; D018533:Biomass; D002713:Chlorine / Q000494:pharmacology*; D003470:Culture Media; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics / Q000502:physiology*; D005978:Glutathione / Q000096:biosynthesis*; D007700:Kinetics; D010101:Oxygen Consumption; D012973:Sodium Hypochlorite / Q000494:pharmacology; D013438:Sulfhydryl Compounds / Q000378:metabolism
D003470:Culture Media; D013438:Sulfhydryl Compounds; D002713:Chlorine; D012973:Sodium Hypochlorite; D005978:Glutathione