Clinicopathologic features and prognostic factors of primary extranodal non-Hodgkin's lymphomas in Turkey.
Clinical, histopathologic, and prognostic features of 114 patients with primary extranodal non-Hodgkin's lymphoma were evaluated. Median age of the patients was 48 (range, 15-76) and the ratio of male/female was 55/59. Thirty-seven patients had stage 1, 55 patients stage II, 6 patients stage III, and 16 patients stage IV. The most common sites of primary extranodal non-Hodgkin's lymphoma were the gastrointestinal (GI) tract and head-neck region. Stomach (66%) and tonsils (33%) were the most frequently involved organ in GI tract and head-neck region, respectively. Eighty percent of patients had intermediate or high-grade lymphomas, 20% had low-grade subtypes. Complete remission was achieved in 83% of all patients with chemotherapy +/- radiotherapy +/- surgery. Overall and disease-free survival at 5 years were 63% and 59%, respectively. In conclusion, clinical and histopathologic characteristics and prognosis of our cases with primary extranodal non-Hodgkin's lymphoma were usually similar to those of the cases in Western countries with some differences in the incidence of some specific primary extranodal non-Hodgkin's lymphomas and in the histopathologic subtypes.
Arican
A
A
Department of Medical Oncology, Baŝkent University, Faculty of Medicine, Ankara, Turkey.
Dinçol
D
D
Akbulut
H
H
Onur
H
H
Demirkazik
A
A
Cay
F
F
Içli
F
F
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D018572:Disease-Free Survival; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000453:epidemiology; D006258:Head and Neck Neoplasms / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008228:Lymphoma, Non-Hodgkin / Q000145:classification / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012074:Remission Induction; D012737:Sex Factors; D013274:Stomach Neoplasms / Q000453:epidemiology; D015996:Survival Rate; D014067:Tonsillar Neoplasms / Q000453:epidemiology; D014421:Turkey / Q000453:epidemiology