title: Use of minimally modified antisense oligonucleotides for specific inhibition of gene expression.
authors.affiliation: Hoechst Marion Roussel Deutschland GmbH, Frankfurt am Main, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Uhlmann
authors.forename: A
authors.initials: A
authors.lastname: Peyman
authors.forename: A
authors.initials: A
authors.lastname: Ryte
authors.forename: A
authors.initials: A
authors.lastname: Schmidt
authors.forename: E
authors.initials: E
authors.lastname: Buddecke
mesh_terms: D000818:Animals; D001483:Base Sequence; D001692:Biological Transport; D002460:Cell Line; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D015195:Drug Design; D005786:Gene Expression Regulation / Q000187:drug effects*; D016259:Genes, myc / Q000187:drug effects; D020319:Oligodeoxyribonucleotides, Antisense / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D018629:Spectrometry, Mass, Secondary Ion / Q000379:methods; D013329:Structure-Activity Relationship; D013873:Thionucleotides
chemical_list: D020319:Oligodeoxyribonucleotides, Antisense; D013873:Thionucleotides