title: Acyclic structural variants of growth hormone secretagogue L-692,429.
abstract: Systematic investigation of acyclic analogs of L-692,429, the prototype benzolactam growth hormone secretagogue, has helped to further define the structural requirements for the release of growth hormone from rat pituitary cells for this class of secretagogues.
authors.affiliation: Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, NJ 07065, USA.
authors.forename: P
authors.initials: P
authors.lastname: Lin
authors.forename: J M
authors.initials: JM
authors.lastname: Pisano
authors.forename: W R
authors.initials: WR
authors.lastname: Schoen
authors.forename: K
authors.initials: K
authors.lastname: Cheng
authors.forename: W W
authors.initials: WW
authors.lastname: Chan
authors.forename: B S
authors.initials: BS
authors.lastname: Butler
authors.forename: R G
authors.initials: RG
authors.lastname: Smith
authors.forename: M H
authors.initials: MH
authors.lastname: Fisher
authors.forename: M J
authors.initials: MJ
authors.lastname: Wyvratt
mesh_terms: D000818:Animals; D001552:Benzazepines / Q000737:chemistry* / Q000494:pharmacology; D002478:Cells, Cultured; D013006:Growth Hormone / Q000378:metabolism; D015394:Molecular Structure; D010902:Pituitary Gland / Q000737:chemistry / Q000187:drug effects; D051381:Rats; D013777:Tetrazoles / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D001552:Benzazepines; D013777:Tetrazoles; C081455:L 692429; D013006:Growth Hormone