title: Pulmonary alveolar-septal amyloidosis presenting as heart failure with unilateral pleural effusion: a case report.
abstract: We report a case of pulmonary alveolar-septal amyloidosis associated with chylothorax and paraproteinemia initially presenting as congestive heart failure with unilateral pleural effusion. A 72-year-old man was initially diagnosed with congestive heart failure based on the correlation of clinical manifestation and chest radiography. Concentric left ventricular hypertrophy with mild hypokinesis of the left ventricle was found on cardiac echography. Thoracocentesis was performed for right-sided pleural effusion, which persisted despite medical treatment; chylous exudate was aspirated. Because the etiology of the exudative pleural effusion was undetermined, the patient underwent a thoracotomy that showed pulmonary alveolar-septal amyloidosis. Immunoglobulin M paraproteinemia was identified by serum immunoelectrophoresis. We conclude that it is imperative to search for the cause of an undetermined exudative pleural effusion, with particular attention to chylothorax and amyloidosis as the differential diagnoses.
authors.affiliation: Department of Chest Medicine, Taipei Veterans General Hospital, Taiwan, ROC.
authors.forename: Y Y
authors.initials: YY
authors.lastname: Liu
authors.forename: Y C
authors.initials: YC
authors.lastname: Lee
authors.forename: T Y
authors.initials: TY
authors.lastname: Chou
authors.forename: R P
authors.initials: RP
authors.lastname: Perng
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006333:Heart Failure / Q000209:etiology*; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis*; D008297:Male; D010996:Pleural Effusion / Q000209:etiology*