title: [Screening of cancerous and precancerous lesions of the oral mucosa in an at-risk population].
abstract: Early diagnosis of oral carcinomas allows a limitation of functional consequences of surgical treatment. A prospective study was designed in 270 alcoholic patients. We practiced a clinical examination of the oral cavity by a stomatologist followed by a Toluidin blue test. The clinical examination permitted to detect 1 carcinoma and 23 leukoplakias. The Toluidin blue test revealed one more carcinoma and two leukoplakias more. The early diagnosis of oral carcinomas in alcoholics patients gives them a better survival. The Toluidin blue test could be proposed as an aid to early diagnosis of these carcinomas.
authors.affiliation: Service de Chirurgie Maxillo-Faciale et Stomatologie, Hôpital Beaujon, Clichy.
authors.forename: C
authors.initials: C
authors.lastname: Vacher
authors.forename: M
authors.initials: M
authors.lastname: Legens
authors.forename: B
authors.initials: B
authors.lastname: Rueff
authors.forename: J P
authors.initials: JP
authors.lastname: Lezy
mesh_terms: D000437:Alcoholism / Q000150:complications*; D002277:Carcinoma / Q000175:diagnosis; D004396:Coloring Agents; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007972:Leukoplakia, Oral / Q000175:diagnosis; D008297:Male; D008403:Mass Screening; D009062:Mouth Neoplasms / Q000175:diagnosis*; D011230:Precancerous Conditions / Q000175:diagnosis*; D011446:Prospective Studies; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*; D015996:Survival Rate; D014048:Tolonium Chloride
chemical_list: D004396:Coloring Agents; D014048:Tolonium Chloride
vernacular_title: Dépistage des lésions cancéreuses et pré-cancéreuses de la muqueuse buccale dans une population à risque.