title: Methotrexate and emerging therapies.
abstract: More publications in the medical literature have described the clinical efficacy and toxicity of methotrexate (MTX) than of any other drug ever used for rheumatic diseases. A knowledgeable clinical can thus rely on evidence-based medicine to guide the use of this agent. Because MTX is not remission-inducing, many new therapies are being combined with it in order to achieve a greater therapeutic response. This trend will likely continue and expand as more novel agents are introduced.
authors.affiliation: Department of Medicine, Albany Medical College, New York 12208-3479, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Kremer
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects*
chemical_list: D018501:Antirheumatic Agents; D008727:Methotrexate