Intrabody tissue-specific delivery of antisense conjugates in animals: ligand-linker-antisense oligomer conjugates.
Duff
R J
RJ
Department of Biochemistry, Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland 21225, USA.
Deamond
S F
SF
Roby
C
C
Zhou
Y
Y
Ts'o
P O
PO
D000818:Animals; D001692:Biological Transport; D006528:Carcinoma, Hepatocellular; D003854:Deoxyribonucleotides; D006001:Glycoconjugates / Q000138:chemical synthesis; D006801:Humans; D008024:Ligands; D008113:Liver Neoplasms; D008297:Male; D008657:Metabolic Clearance Rate; D051379:Mice; D020319:Oligodeoxyribonucleotides, Antisense / Q000138:chemical synthesis* / Q000737:chemistry / Q000493:pharmacokinetics*; D010761:Phosphorus Radioisotopes; D011865:Radioisotope Dilution Technique; D013462:Sulfur Radioisotopes; D013873:Thionucleotides; D014018:Tissue Distribution; D014407:Tumor Cells, Cultured
D003854:Deoxyribonucleotides; D006001:Glycoconjugates; D008024:Ligands; D020319:Oligodeoxyribonucleotides, Antisense; D010761:Phosphorus Radioisotopes; D013462:Sulfur Radioisotopes; D013873:Thionucleotides