title: The intronerator: exploring introns and alternative splicing in Caenorhabditis elegans.
abstract: The Intronerator (http://www.cse.ucsc.edu/ approximately kent/intronerator/ ) is a set of web-based tools for exploring RNA splicing and gene structure in Caenorhabditis elegans. It includes a display of cDNA alignments with the genomic sequence, a catalog of alternatively spliced genes and a database of introns. The cDNA alignments include >100 000 ESTs and almost 1000 full-length cDNAs. ESTs from embryos and mixed stage animals as well as full-length cDNAs can be compared in the alignment display with each other and with predicted genes. The alt-splicing catalog includes 844 open reading frames for which there is evidence of alternative splicing of pre-mRNA. The intron database includes 28 478 introns, and can be searched for patterns near the splice junctions.
authors.affiliation: Department of Biology, Center for Molecular Biology of RNA, Sinsheimer Laboratories, University of California at Santa Cruz, Santa Cruz, CA 95064, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Kent
authors.forename: A M
authors.initials: AM
authors.lastname: Zahler
mesh_terms: D017398:Alternative Splicing; D000818:Animals; D001483:Base Sequence; D017173:Caenorhabditis elegans / Q000235:genetics*; D017931:DNA Primers; D003628:Database Management Systems; D016208:Databases, Factual; D020407:Internet; D007438:Introns; D016415:Sequence Alignment
chemical_list: D017931:DNA Primers