title: Escherichia coli resistance to chlorine and glutathione synthesis in response to oxygenation and starvation.
abstract: Reduced glutathione (GSH) levels and resistance to chlorine were measured for two isogenic Escherichia coli strains stressed by oxygenation and/or starvation. The E. coli mutant deficient in GSH was not more sensitive to the oxidant than its parent strain when the bacteria were cultured with a low oxygenation rate. Starvation or oxygenation increased the resistance of the parent strain to chlorine, while the resistance of the deficient strain remained unchanged.
authors.affiliation: LCPE-LSE, UMR Université CNRS 7564, France.
authors.forename: S
authors.initials: S
authors.lastname: Saby
authors.forename: P
authors.initials: P
authors.lastname: Leroy
authors.forename: J C
authors.initials: JC
authors.lastname: Block
mesh_terms: D000332:Aerobiosis; D018533:Biomass; D002713:Chlorine / Q000494:pharmacology*; D003470:Culture Media; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics / Q000502:physiology*; D005978:Glutathione / Q000096:biosynthesis*; D007700:Kinetics; D010101:Oxygen Consumption; D012973:Sodium Hypochlorite / Q000494:pharmacology; D013438:Sulfhydryl Compounds / Q000378:metabolism
chemical_list: D003470:Culture Media; D013438:Sulfhydryl Compounds; D002713:Chlorine; D012973:Sodium Hypochlorite; D005978:Glutathione