title: Intra-arterial infusion of 5-fluorouracil, leucovorin and cisplatin for primary adenocarcinoma of the urinary bladder.
abstract: BACKGROUND
  Primary invasive adenocarcinoma of the urinary bladder was diagnosed in a 59-year-old man with a 6-month history of macrohematuria.
  
  
  METHODS
  He was treated with intra-arterial infusion of 5-fluorouracil, leucovorin and cisplatin and underwent radical cystectomy and construction of ileal conduit.
  
  
  RESULTS
  The pathologic examination of the specimen revealed no viable malignant cells.
  
  
  CONCLUSIONS
  5-Fluorouracil combined with leucovorin and/or cisplatin has been used in the treatment of gastrointestinal adenocarcinoma and may be useful in primary adenocarcinoma of the bladder.
authors.affiliation: Department of Urology, Kyoto National Hospital, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Awakura
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
authors.forename: S
authors.initials: S
authors.lastname: Fukuzawa
authors.forename: M
authors.initials: M
authors.lastname: Nonomura
authors.forename: T
authors.initials: T
authors.lastname: Fukuyama
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000188:drug therapy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage*; D003558:Cystoscopy; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D007261:Infusions, Intra-Arterial; D002955:Leucovorin / Q000008:administration & dosage*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000628:therapy
chemical_list: D002945:Cisplatin; D002955:Leucovorin; D005472:Fluorouracil