title: Testicular lymphoma with bone/bone marrow metastases illustrated by scrotal sonography, spinal MRI, and total body Tc-99m HMDP and Tc-99m MIBI images.
abstract: An 83-year-old man with testicular lymphoma demonstrated progressive scrotal enlargement with non-homogeneity sonographically and abnormally increased uptake in the scrotum of Tc-99m HMDP and Tc-99m MIBI scintigraphically. Extensive bone/bone marrow metastases were exhibited by Tc-99m MIBI and Tc-99m HMDP scintigraphies and MRI of the spine. In addition, focal/tubular activity of the femoral bone marrow on Tc-99m MIBI imaging was consistent with skeletal scintigraphic findings. It is emphasized that Tc-99m MIBI total body imaging enabled the demonstration of testicular lymphoma as increased uptake and the illustration of skeletal/bone marrow metastases as diffuse and/or focal increased uptake, especially focal/tubular MIBI activity of the femoral marrow.
authors.affiliation: Nuclear Medicine Service, Lexington VA Medical Center, Kentucky 40511, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Shih
authors.forename: D S
authors.initials: DS
authors.lastname: Kwolek
authors.forename: B
authors.initials: B
authors.lastname: Lahr
mesh_terms: D000368:Aged; D019046:Bone Marrow Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000556:secondary; D001859:Bone Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000556:secondary; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate / Q000031:analogs & derivatives*; D017256:Technetium Tc 99m Sestamibi; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging*; D014463:Ultrasonography
chemical_list: D019275:Radiopharmaceuticals; C024226:technetium Tc 99m hydroxymethylene diphosphonate; D017256:Technetium Tc 99m Sestamibi; D013669:Technetium Tc 99m Medronate