title: [Electron microscope study of lung carcinoid].
abstract: 123 lung carcinoids were studied, 32 of them electron-microscopically. Ultrastructural features were evaluated with the use of multivariate analysis. The most informative ultrastructural features were the following: correlation between differentiated and undifferentiated cells, the number of cytoplasm organoids including endocrine granules, degree of nuclei polymorphism and their size, specialized contacts, mitoses. Up to 18% of carcinoids, on the average, need ultrastructural verification of the anaplasia degree, this percentage increasing to 27.2% in atypical carcinoids. The above ultrastructural criteria allow to specify malignant potential of carcinoids, facilitate differential diagnosis and make their prognosis.
authors.affiliation: N. N. Blokhin Cancer Research Center, Moscow.
authors.forename: N T
authors.initials: NT
authors.lastname: Raĭklin
authors.forename: E A
authors.initials: EA
authors.lastname: Smirnova
authors.forename: B E
authors.initials: BE
authors.lastname: Polotskiĭ
authors.forename: T G
authors.initials: TG
authors.lastname: Glazkova
authors.forename: B Kh
authors.initials: BKh
authors.lastname: Bebezov
authors.forename: M I
authors.initials: MI
authors.lastname: Davydov
mesh_terms: D002276:Carcinoid Tumor / Q000401:mortality / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D011379:Prognosis; D016019:Survival Analysis
vernacular_title: Elektronno-mikroskopicheskoe issledovanie kartsinoidov legkogo.