title: Extensive mediastinal lymphadenopathy in an adult immunocompetent woman caused by Mycobacterium avium complex.
abstract: We report a case of extensive mediastinal lymphadenopathy in a 29-year-old immunocompetent woman, which was thought to be caused by Mycobacterium tuberculosis (MTB). Chest radiographs showed deterioration while the patient was receiving antituberculous medication for 8 months. After isolation of Mycobacterium avium complex (MAC) from a lymph node aspiration biopsy and switch to a MAC-specific therapeutic regimen, the lesion almost completely disappeared within 1 year. To our knowledge, this is the first report of an extensive mediastinal lymphadenopathy caused by MAC in an immunocompetent adult.
authors.affiliation: Department of Clinical Medicine, Research Center, Borstel, Germany. ugreinert@fz-borstel.de
authors.forename: U
authors.initials: U
authors.lastname: Greinert
authors.forename: S
authors.initials: S
authors.lastname: Rüsch-Gerdes
authors.forename: E
authors.initials: E
authors.lastname: Vollmer
authors.forename: M
authors.initials: M
authors.lastname: Schlaak
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007121:Immunocompetence; D008206:Lymphatic Diseases / Q000188:drug therapy / Q000382:microbiology*; D008477:Mediastinal Diseases / Q000188:drug therapy / Q000382:microbiology*; D015270:Mycobacterium avium-intracellulare Infection / Q000188:drug therapy; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*