title: Hypersensitivity reaction to carboplatin during treatment for ovarian cancer: successful resolution by replacement with cisplatin.
abstract: Development of hypersensitivity reactions to carboplatin (CP) during cancer treatment makes optimal chemotherapy difficult to achieve. Many approaches have previously been used following the development of reactions to CP. We report on a patient with ovarian cancer who developed a hypersensitivity reaction to CP. The patient was successfully treated following replacement of carboplatin with cisplatin.
authors.affiliation: Department of Obstetrics and Gynecology, Fukui Medical University, Yoshida-Gun, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Shukunami
authors.forename: T
authors.initials: T
authors.lastname: Kurokawa
authors.forename: M
authors.initials: M
authors.lastname: Kubo
authors.forename: M
authors.initials: M
authors.lastname: Kaneshima
authors.forename: N
authors.initials: N
authors.lastname: Kamitani
authors.forename: F
authors.initials: F
authors.lastname: Kotsuji
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D016190:Carboplatin / Q000009:adverse effects* / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents; D016190:Carboplatin; D002945:Cisplatin