title: Further hypotensive metabolites from Verbesina caracasana.
abstract: After the isolation of caracasanamide and caracasandiamide, further hypotensive components of Verbesina caracasana were shown to be N3-prenylagmatine, N1-3',4'-dimethoxycinnamoylagmatine, agmatine and galegin (prenylguanidine). The structures were assigned on the basis of the spectral data of both metabolites and products from their alkaline hydrolyses. A pharmacological analysis of these products is also presented.
authors.affiliation: Centro Chimica dei Recettori, Università Cattolica, Rome, Italy. g.dellemonache@uniserv.ccr.rm.cnr.it
authors.forename: G
authors.initials: G
authors.lastname: Delle Monache
authors.forename: A R
authors.initials: AR
authors.lastname: Volpe
authors.forename: F
authors.initials: F
authors.lastname: Delle Monache
authors.forename: A
authors.initials: A
authors.lastname: Vitali
authors.forename: B
authors.initials: B
authors.lastname: Botta
authors.forename: R
authors.initials: R
authors.lastname: Espinal
authors.forename: S C
authors.initials: SC
authors.lastname: De Bonnevaux
authors.forename: C
authors.initials: C
authors.lastname: De Luca
authors.forename: M
authors.initials: M
authors.lastname: Botta
authors.forename: F
authors.initials: F
authors.lastname: Corelli
authors.forename: M
authors.initials: M
authors.lastname: Carmignani
mesh_terms: D000818:Animals; D000959:Antihypertensive Agents / Q000737:chemistry / Q000302:isolation & purification*; D019659:Asteraceae / Q000737:chemistry*; D013058:Mass Spectrometry; D051381:Rats
chemical_list: D000959:Antihypertensive Agents