title: Cytomegalovirus pneumonitis as an initial presentation in an HIV-infected patient.
abstract: Human immunodeficiency (HIV) infection often presents with an unusual symptom complex. Although cytomegalovirus (CMV) is a frequent opportunistic infection in the late stage of acquired immunodeficiency syndrome (AIDS), CMV pneumonitis as an initial manifestation of HIV infection is not documented in the medical literature. We report a previously healthy patient with bilateral interstitial pulmonary infiltrates who was found to have CMV pneumonitis; only later was HIV virus infection diagnosed. Cytomegalovirus is a frequently isolated pathogen from respiratory secretions in AIDS patients. The role of CMV as a sole pulmonary pathogen is controversial. After exclusion of other pathogens, CMV was demonstrated by histological changes and viral culture in our case. This case indicates that pulmonary infiltrates presenting as the first manifestation of HIV infection can be caused by CMV infection.
authors.affiliation: Department of Medicine, Norwalk Hospital, Yale University School of Medicine, USA.
authors.forename: G G
authors.initials: GG
authors.lastname: Zhao
authors.forename: J Y
authors.initials: JY
authors.lastname: Li
authors.forename: E
authors.initials: E
authors.lastname: Atlas
authors.forename: J P
authors.initials: JP
authors.lastname: Cleary
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000821:virology; D000914:Antibodies, Viral / Q000032:analysis; D001706:Biopsy; D003587:Cytomegalovirus / Q000276:immunology / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000821:virology; D003937:Diagnosis, Differential; D006678:HIV / Q000276:immunology; D015483:HIV Antibodies / Q000032:analysis; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology / Q000821:virology; D008297:Male; D008875:Middle Aged; D011024:Pneumonia, Viral / Q000175:diagnosis* / Q000821:virology; D013902:Radiography, Thoracic
chemical_list: D000914:Antibodies, Viral; D015483:HIV Antibodies