[Preoperative autologous blood donation in coronary artery bypass grafting in elderly patients].
Allogeneic blood transfusion still carries risks of transfusion reaction and infection. We examined the effect of a preoperative autologous blood donation (800-1,200 g) by subcutaneous epoetin alpha injection on a series of patients undergoing elective coronary artery bypass grafting (CABG). CABG was being performed with increased frequency in elderly patients. We have performed CABG in 18 patients over 65 years of age (elderly group). These patients were compared with 20 patients under 64 years of age (younger group). Postoperative bleeding and allogeneic blood transfusion were significantly larger in quantity in the elderly group than the younger group (p < 0.05). The incidence of allogeneic blood usage was significantly higher in the elderly group than the younger group (p < 0.05). Therefore, a preoperative autologous blood donation in CABG was considered to be not so effective for saving allogeneic blood transfusion and preventing transfusion reaction or infection in elderly patients.
Hibi
M
M
Department of Surgery, Aichi Prefectural Owari Hospital, Ichinomiya, Japan.
Ohshima
H
H
Murakami
F
F
Tomida
Y
Y
Matsuura
A
A
Yoshida
K
K
D000368:Aged; D001804:Blood Transfusion, Autologous; D006348:Cardiac Surgical Procedures / Q000379:methods; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male