title: [Two cases of malignant and benign systemic mastocytosis].
abstract: The authors give a short account about the clinical histories of two patients: one with malignant systemic mastocytosis resulting in acute myeloid leukaemia, the other with indolent systemic mastocytosis. A brief review is reported about the physiological and pathophysiological role of mastocyte system. Benign and malignant types, classification of mastocyte proliferation are detailed, several distinct characteristics of clinical appearance, main aspects of diagnosis, therapy and prognosis in patients with different forms of systemic mastocytosis are briefly discussed.
authors.affiliation: II. Belgyógyászati Osztály, Szent György Kórház, Székesfehérvár.
authors.forename: P
authors.initials: P
authors.lastname: Mezei
authors.forename: Z
authors.initials: Z
authors.lastname: Bencsik
authors.forename: B
authors.initials: B
authors.lastname: Vicze
authors.forename: K
authors.initials: K
authors.lastname: Simon
authors.forename: L
authors.initials: L
authors.lastname: István
authors.forename: L
authors.initials: L
authors.lastname: Pajor
mesh_terms: D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D005029:Ethylenediamines / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007665:Ketotifen / Q000627:therapeutic use; D008297:Male; D008415:Mastocytosis / Q000145:classification* / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D010024:Osteoporosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D010026:Osteosclerosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D010384:Pelvic Bones / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D016896:Treatment Outcome
chemical_list: D005029:Ethylenediamines; D006634:Histamine H1 Antagonists; C004664:chloropyramine; D007665:Ketotifen
vernacular_title: Malignus és benignus systemás mastocytosis egy-egy esete.