title: Primary hypothyroidism associated with leishmaniasis in a dog.
abstract: A case of primary hypothyroidism associated with leishmaniasis is described in a four-year-old, male Yorkshire terrier. Clinical diagnosis of hypothyroidism was confirmed by a low baseline serum tetraiodothyronine (T4), a reduced response to thyroid-stimulating hormone (TSH) stimulation, an increased serum TSH concentration, and scintigraphic thyroid gland examination. Examination of a thyroid biopsy showed many Leishmania amastigotes, both inside and outside of macrophages, together with signs of follicular atrophy.
authors.affiliation: Dipartimento di Scienze Cliniche Veterinarie, Università degli Studi di Napoli Federico II, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Cortese
authors.forename: G
authors.initials: G
authors.lastname: Oliva
authors.forename: P
authors.initials: P
authors.lastname: Ciaramella
authors.forename: A
authors.initials: A
authors.lastname: Persechino
authors.forename: B
authors.initials: B
authors.lastname: Restucci
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D004285:Dogs; D017809:Fatal Outcome; D007037:Hypothyroidism / Q000209:etiology / Q000662:veterinary*; D016773:Leishmaniasis, Cutaneous / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D008297:Male; D013960:Thyroid Function Tests / Q000662:veterinary