title: [Heart failure caused by myocardial hypertrophy in diabetic fetopathy].
abstract: Diabetic fetopathy is still a common clinical problem correlated with a high morbidity of the neonate. These children are often macrosome, suffer from respiratory distress syndrome due to delayed lung maturity, acidosis, hypoglycaemia, electrolyte-imbalances and polycythaemia. We describe a male neonate with diabetic fetopathy as a result of gestational diabetes of the mother. In addition to the symptoms described above, our patient clinically presented with severe hypertrophy of the right ventricle associated with intrauterine heart failure. The boy was born with serious prenatal asphyxia which made initial neonatal intensive care treatment necessary. The hypertrophic cardiomyopathy normalized within 6 weeks after birth without further treatment. Different causes of a hypertrophic cardiomyopathy (infections, metabolic disorders, neurologic affections, syndromes) could be ruled out, so that the diabetic fetopathy was the most probable cause for the condition. If we are looking at the heart only, this case-report suggests a good prognosis of septumhypertrophy as well as right ventricular hypertrophy in patients with diabetic fetopathy. The case also elucidates that not only the diabetes type I can entail serious fetal damage but also gestational diabetes can. Therefore, in suspect mothers screening for gestational diabetes should be expanded to oral glucose tolerance testing.
authors.affiliation: Kinderkrankenhaus auf der Bulb, Hannover.
authors.forename: A
authors.initials: A
authors.lastname: Krautzig
authors.forename: J
authors.initials: J
authors.lastname: Christoph
authors.forename: E
authors.initials: E
authors.lastname: Kattner
mesh_terms: D000328:Adult; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D005320:Fetal Macrosomia / Q000175:diagnosis*; D006333:Heart Failure / Q000175:diagnosis; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000175:diagnosis*; D011379:Prognosis; D016216:Ultrasonography, Prenatal
vernacular_title: Herzinsuffizienz infolge Myokardhypertrophie bei diabetischer Fetopathie.