Toxic effect of synthetic pyrethroid permethrin on the enzyme system of the freshwater fish Channa striatus.
Treatment with 40% and 80% of the LC50 (24h) of the pyrethroid permethrin after 24h exposure causes significant reduction in the activity of lactate dehydrogenase and cytochrome oxidase and enhanced the succinate dehydrogenase activity in the tissues of the freshwater fish Channa striatus. The results indicate that permethrin blocks aerobic as well as anaerobic metabolism in the exposed fishes.
Singh
A
A
Department of Zoology, University of Gorakhpur, India.
Srivastava
V K
VK
D000818:Animals; D004305:Dose-Response Relationship, Drug; D003576:Electron Transport Complex IV / Q000037:antagonists & inhibitors; D004789:Enzyme Activation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000633:toxicity; D005399:Fishes / Q000378:metabolism*; D005618:Fresh Water; D007306:Insecticides / Q000633:toxicity*; D007770:L-Lactate Dehydrogenase / Q000037:antagonists & inhibitors; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D009132:Muscles / Q000187:drug effects / Q000201:enzymology; D026023:Permethrin; D011722:Pyrethrins / Q000633:toxicity*; D013385:Succinate Dehydrogenase / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000633:toxicity*
D004791:Enzyme Inhibitors; D007306:Insecticides; D011722:Pyrethrins; D014874:Water Pollutants, Chemical; D026023:Permethrin; D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase; D003576:Electron Transport Complex IV