title: Aortic valve replacement for aortic regurgitation caused by aortitis.
abstract: Between January 1984 and December 1998, 19 patients (16 with Takayasu's arteritis, 3 with non-Takayasu's aortitis) underwent surgical treatment for aortic regurgitation resulting from the aortitis. Of the 19 patients, 14 had aortic valve replacement (AVR) and 5 had aortic root replacement. One patient (5.3%) died of graft infection during the hospital stay. During the follow-up period, 1 (5.6%) of the 18 postoperative patients died of paravalvular leakage due to valve detachment, which also required redo-operations in 2 patients with non-Takayasu's aortitis. Both patients were operated on during the active phase of the inflammation without perioperative steroid therapy. Although transmural pledgeted sutures were used for replacement of the detached prosthetic valve in 1 of these 2 patients, disruption of the aortic wall resulted in recurrence of valve detachment. In the other patient, aortic root replacement was successfully performed with the Cabrol technique in the second operation. Perioperaitve steroid therapy plays an important role in preventing complications after AVR when the valve replacement is carried out during the active phase of the inflammation, and for patients with non-Takayasu's aortitis, aortic root replacement should be considered to reduce the tension on the suture line and the native aortic valve annulus.
authors.affiliation: Second Department of Surgery, Kurume University School of Medicine, Japan. aoyagi@med.kurume-u.ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Aoyagi
authors.forename: S
authors.initials: S
authors.lastname: Fukunaga
authors.forename: E
authors.initials: E
authors.lastname: Tayama
authors.forename: N
authors.initials: N
authors.lastname: Hayashida
authors.forename: H
authors.initials: H
authors.lastname: Akashi
authors.forename: T
authors.initials: T
authors.lastname: Kawara
mesh_terms: D000328:Adult; D000368:Aged; D001021:Aortic Valve / Q000601:surgery; D001022:Aortic Valve Insufficiency / Q000209:etiology / Q000601:surgery*; D001025:Aortitis / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation / Q000401:mortality; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate