Leydig-cell tumors caused by an activating mutation of the gene encoding the luteinizing hormone receptor.
Liu
G
G
Department of Pediatrics, Northwestern University Medical School and Children's Memorial Institute for Education and Research, Chicago, IL 60614, USA.
Duranteau
L
L
Carel
J C
JC
Monroe
J
J
Doyle
D A
DA
Shenker
A
A
D002648:Child; D000242:Cyclic AMP / Q000096:biosynthesis; D006801:Humans; D007295:Inositol Phosphates / Q000096:biosynthesis; D007984:Leydig Cell Tumor / Q000150:complications / Q000235:genetics* / Q000473:pathology; D008297:Male; D009154:Mutation; D011629:Puberty, Precocious / Q000209:etiology*; D011974:Receptors, LH / Q000235:genetics* / Q000378:metabolism; D013736:Testicular Neoplasms / Q000150:complications / Q000235:genetics* / Q000473:pathology; D013737:Testis / Q000473:pathology
D007295:Inositol Phosphates; D011974:Receptors, LH; D000242:Cyclic AMP