title: Malignant rhabdoid tumor beside benign skin mesenchymal neoplasm with myofibromatous features.
abstract: Only a few reports of primary cutaneous rhabdoid tumors have been published. We describe the case of a 3-month-old female patient who developed a rhabdoid type cutaneous sarcomatoid neoplasm in her upper back, close to a benign myofibromatous proliferation of infancy. The lesion was studied both by light microscopy and immunohistochemically. Flow cytometry was performed showing a DNA diploid profile of the malignant tumor. The pathological findings suggest a mesenchymal origin (hemangiopericytic or myofibroblastic type) for both tumors. The patient was surgically treated, but she died nine months later.
authors.affiliation: Department of Dermatology, Hospital Universitario de Canarias, University of La Laguna, Tenerife, Spain. mgarciab@ull.es
authors.forename: M
authors.initials: M
authors.lastname: García-Bustínduy
authors.forename: H
authors.initials: H
authors.lastname: Alvarez-Arguelles
authors.forename: F
authors.initials: F
authors.lastname: Guimerá
authors.forename: C
authors.initials: C
authors.lastname: García-Castro
authors.forename: R
authors.initials: R
authors.lastname: Sánchez-González
authors.forename: N
authors.initials: N
authors.lastname: Hernández
authors.forename: L
authors.initials: L
authors.lastname: Diaz-Flores
authors.forename: R
authors.initials: R
authors.lastname: García-Montelongo
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D002469:Cell Separation; D004273:DNA, Neoplasm / Q000032:analysis; D017809:Fatal Outcome; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D008637:Mesenchymoma / Q000737:chemistry / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D011003:Ploidies; D018335:Rhabdoid Tumor / Q000737:chemistry / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000737:chemistry / Q000235:genetics / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm