Prolonged mivacurium-induced neuromuscular block. Case report.
A 38-year-old white male patient was admitted to the hospital for elective surgery. General anesthesia was performed with propofol, alfentanil, nitrous oxide and mivacurium as neuromuscular blocker. Seven months before he had the same surgery without anesthetic problems (he received: propofol, vecuronium bromide, fentanil, nitrous oxide). Neuromuscular monitoring was carried out because the patient was included in a study assessing the clinical effect of mivacurium in microlaryngoscopy surgery. After mivacurium administration the first signs of recovery from neuromuscular block were observed after 255 min. The tracheal tube was withdrawn after 410 min from mivacurium administration, at this time the T1 was 80% of the control values and 7 min later the T1 reached 98%.
Arcioni
R
R
Anesthesia and Intensive Care Medicine Institute, University of Rome, La Sapienza.
Sanfilippo
M
M
Romano
R
R
Lappa
A
A
Mercieri
M
M
Müller
T M
TM
Marcotullio
D
D
D000328:Adult; D000762:Anesthesia Recovery Period; D006801:Humans; D007546:Isoquinolines / Q000009:adverse effects*; D007828:Laryngoscopy; D008297:Male; D000077590:Mivacurium; D019148:Neuromuscular Blockade; D003473:Neuromuscular Nondepolarizing Agents / Q000009:adverse effects*
D007546:Isoquinolines; D003473:Neuromuscular Nondepolarizing Agents; D000077590:Mivacurium