Effects of ginseng radix on sugar absorption in the small intestine.
Ginseng radix (GR) is often used in traditional Japanese kampo medicine. We studied the effect of GR on glucose and maltose transport in rat and human duodenal mucosa by Ussing's method, and on smooth muscle movement in rat duodenal muscle by Magnus' method. GR inhibited absorption of glucose or maltose in rat and human duodenal mucosa, but increased duodenal muscle movement. It suggests that the inhibition of sugar absorption by GR is more dominant than enhancement of duodenal muscle movement by GR.
Onomura
M
M
Department of Metabolism and Clinical Nutrition, Faculty of Medicine, Kyoto University, Japan.
Tsukada
H
H
Fukuda
K
K
Hosokawa
M
M
Nakamura
H
H
Kodama
M
M
Ohya
M
M
Seino
Y
Y
D000328:Adult; D000818:Animals; D005260:Female; D005947:Glucose / Q000493:pharmacokinetics*; D006801:Humans; D066298:In Vitro Techniques; D007202:Indicators and Reagents; D007408:Intestinal Absorption / Q000187:drug effects*; D007413:Intestinal Mucosa / Q000187:drug effects; D008297:Male; D008320:Maltose / Q000493:pharmacokinetics*; D008875:Middle Aged; D009130:Muscle, Smooth / Q000187:drug effects; D005894:Panax; D010528:Peristalsis / Q000187:drug effects; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar
D007202:Indicators and Reagents; D008320:Maltose; D005947:Glucose