Combination cyclosporine and (hydroxy)chloroquine in rheumatoid arthritis.
Antimalarials are attractive candidates for combination therapy. In vitro experiments have revealed a synergistic mode of action of cyclosporine and chloroquine which could not, however, be confirmed in a clinical trial.
Dijkmans
B A
BA
Rheumatology Department, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands. secr.reumatology@azvu.nl
Landewé
R B
RB
van den Borne
B E
BE
Breedveld
F C
FC
D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D016572:Cyclosporine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use*; D016896:Treatment Outcome
D018501:Antirheumatic Agents; D006886:Hydroxychloroquine; D016572:Cyclosporine