title: A novel serotype of enteropathogenic Escherichia coli (EPEC) as a major pathogen in an outbreak of infantile diarrhoea.
abstract: An outbreak of infantile diarrhoea was investigated in 32 children, all <2 years old, in the tropical north of Australia. Rotavirus (63%) and enteropathogenic Escherichia coli (EPEC) (59%) were the most common pathogens identified. Of the 19 EPEC isolates, 14 (74%) were of serotype O126:H12, hitherto unreported as an EPEC serotype. Other pathogens isolated included Salmonella spp. (16%), Campylobacter spp. (3%), Giardia (3%) and Shigella spp. (3%). EPEC-related gastro-enteritis is an uncommon but recognised cause of diarrhoeal outbreaks in Australia and clinicians need to be aware of the possibility of this serotype being implicated. This report highlights the disadvantages of relying on serotyping alone for the recognition of EPEC.
authors.forename: R S
authors.initials: RS
authors.lastname: Barlow
authors.forename: R G
authors.initials: RG
authors.lastname: Hirst
authors.affiliation: Department of Microbiology, Townsville General Hospital, Townsville.
authors.forename: R E
authors.initials: RE
authors.lastname: Norton
authors.affiliation: Department of Microbiology, Townsville General Hospital, Townsville.
authors.forename: C
authors.initials: C
authors.lastname: Ashhurst-Smith
authors.affiliation: National Escherichia coli Reference Laboratory, Victorian Infectious Diseases Reference Laboratory, Melbourne, Australia.
authors.forename: K A
authors.initials: KA
authors.lastname: Bettelheim
mesh_terms: D001315:Australia / Q000453:epidemiology; D003968:Diarrhea, Infantile / Q000453:epidemiology / Q000382:microbiology*; D004196:Disease Outbreaks; D004926:Escherichia coli / Q000145:classification* / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D006367:HeLa Cells; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016133:Polymerase Chain Reaction / Q000379:methods; D012703:Serotyping