title: Visually guided exploration in Huntington disease.
abstract: We compared 24 patients in various stages of Huntington disease (HD) with 26 control patients free from cerebral disorders using a simple visual saccadic tracking test. The two groups were well matched in regard to age, sex, verbal IQ and years of schooling. Test results differed widely. On a time versus error plot, sensitivity (96%) and specificity (100%) were high and the results did not depend on age, education, or disease duration, although an influence of disease stage could be observed. This study shows that a simple saccadic tracking task may be useful in detecting visuomotor disturbances in HD.
authors.affiliation: Neurological Hospital, University of Erlangen-Nuremberg at Erlangen, Germany. christoph.lang@neuro.med.uni-erlangen.de
authors.forename: C J
authors.initials: CJ
authors.lastname: Lang
authors.forename: F M
authors.initials: FM
authors.lastname: Reischies
authors.forename: M
authors.initials: M
authors.lastname: Majer
authors.forename: R F
authors.initials: RF
authors.lastname: Daum
mesh_terms: D000328:Adult; D000368:Aged; D018450:Disease Progression; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011597:Psychomotor Performance / Q000502:physiology; D012438:Saccades / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*