title: Spectrum of opportunistic infections and malignancies in patients with human immunodeficiency virus infection in South Korea.
abstract: To determine the frequency and types of major opportunistic diseases in patients with HIV infection in South Korea, we reviewed the medical records of 173 HIV-infected patients. The patients were seen from 1985 to 1998 at a referral hospital for AIDS in South Korea. Most patients (85%) were male, and 107 (62%) were infected by heterosexual contacts. CD4+ lymphocyte counts at presentation were <200/microL in 27% of the patients. Tuberculosis was the most frequent opportunistic infection (25% of patients), followed by candidiasis (21%), herpes zoster (20%), Pneumocystis carinii pneumonia (10%), cytomegalovirus disease (9.8%). There were no cases of toxoplasmosis. Kaposi's sarcoma developed in 3 patients (1.7%), and non-Hodgkin's lymphoma, in 2 (1.2%). Eleven patients (6.4%) developed peripheral neuropathy, and 8 (4.6%) had HIV encephalopathy. Tuberculosis was the single most important HIV-related infection in South Korean patients.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, 110-744, South Korea.
authors.forename: M D
authors.initials: MD
authors.lastname: Oh
authors.forename: S W
authors.initials: SW
authors.lastname: Park
authors.forename: H B
authors.initials: HB
authors.lastname: Kim
authors.forename: U S
authors.initials: US
authors.lastname: Kim
authors.forename: N J
authors.initials: NJ
authors.lastname: Kim
authors.forename: H J
authors.initials: HJ
authors.lastname: Choi
authors.forename: D H
authors.initials: DH
authors.lastname: Shin
authors.forename: J S
authors.initials: JS
authors.lastname: Lee
authors.forename: K
authors.initials: K
authors.lastname: Choe
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000453:epidemiology / Q000401:mortality; D000293:Adolescent; D000328:Adult; D018791:CD4 Lymphocyte Count; D002423:Cause of Death; D003967:Diarrhea / Q000150:complications; D004342:Drug Hypersensitivity / Q000150:complications; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology / Q000401:mortality; D006562:Herpes Zoster / Q000150:complications; D006801:Humans; D007723:Korea / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000150:complications; D011020:Pneumonia, Pneumocystis / Q000150:complications; D015995:Prevalence; D012514:Sarcoma, Kaposi / Q000150:complications; D015996:Survival Rate; D014376:Tuberculosis / Q000150:complications