Polyamino acids as catalysts in asymmetric synthesis.
The use of polyamino acids in asymmetric organic synthesis is reviewed. Particular emphasis is placed on the asymmetric epoxidation of alpha,beta-unsaturated ketones with hydrogen peroxide in the presence of polyalanine or polyleucine, and further transformations of the epoxide products.
Porter
M J
MJ
Department of Chemistry, University of Liverpool, UK.
Roberts
S M
SM
Skidmore
J
J
D000596:Amino Acids / Q000737:chemistry* / Q000378:metabolism; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D004852:Epoxy Compounds / Q000737:chemistry; D006861:Hydrogen Peroxide / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis*; D010455:Peptides / Q000737:chemistry / Q000378:metabolism
D000596:Amino Acids; D004852:Epoxy Compounds; D007659:Ketones; D010455:Peptides; C019529:polyalanine; C027819:polyleucine; D006861:Hydrogen Peroxide