title: Intermittent left coronary occlusion caused by native aortic valve thrombosis in a patient with protein S deficiency.
abstract: A 77-year-old woman presented with chest pain and cardiogenic shock. Transesophageal echocardiography showed a mobile mass occluding intermittently the left coronary ostium. The mass was surgically resected, and histologic examination revealed an organized thrombus. Coagulation study demonstrated a protein S deficiency. This is the first case of aortic thrombosis associated with protein S deficiency, and it is the first time that transesophageal echocardiography provided definite evidence that a mass can cause intermittent left ostium coronary obstruction.
authors.affiliation: Department of Cardiology and Cardiac Surgery, Brest University Hospital, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Jobic
authors.forename: K
authors.initials: K
authors.lastname: Provost
authors.forename: J M
authors.initials: JM
authors.lastname: Larlet
authors.forename: P
authors.initials: P
authors.lastname: Mondine
authors.forename: M
authors.initials: M
authors.lastname: Gilard
authors.forename: J
authors.initials: J
authors.lastname: Boschat
authors.forename: J J
authors.initials: JJ
authors.lastname: Blanc
mesh_terms: D000368:Aged; D001021:Aortic Valve / Q000000981:diagnostic imaging; D006348:Cardiac Surgical Procedures; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D017548:Echocardiography, Transesophageal; D004562:Electrocardiography; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D017293:Protein S / Q000378:metabolism; D018455:Protein S Deficiency / Q000097:blood / Q000150:complications*; D013927:Thrombosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery
chemical_list: D017293:Protein S