A unique effect of clonazepam on frontal lobe seizure control.
In a 16-year-old female, clonazepam (CZP) changed randomly occurring intractable tonic seizures of frontal lobe origin to a few sleep seizures when used as an adjunctive therapy. The significance of this change in the seizure pattern is discussed with an explanation of possible pathophysiologic mechanism.
Obeid
T
T
Neurology Sections, King Khalid and King Fahad National Guard Hospitals, Jeddah, Kingdom of Saudi Arabia.
Awada
A
A
Sayes
N
N
Mousali
Y
Y
Harris
C
C
D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use*; D002998:Clonazepam / Q000627:therapeutic use*; D004829:Epilepsy, Generalized / Q000188:drug therapy*; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans
D000927:Anticonvulsants; D002998:Clonazepam