Lipid-based formulations of antisense oligonucleotides for systemic delivery applications.
Semple
S C
SC
Inex Pharmaceuticals Corporation, Burnaby, British Columbia, Canada.
Klimuk
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SK
Harasym
T O
TO
Hope
M J
MJ
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000627:therapeutic use; D002214:Capsules; D003470:Culture Media; D003902:Detergents; D004139:Dinitrofluorobenzene; D004337:Drug Carriers; D006801:Humans; D007249:Inflammation; D008081:Liposomes; D008175:Lung Neoplasms / Q000188:drug therapy; D008657:Metabolic Clearance Rate; D051379:Mice; D008807:Mice, Inbred BALB C; D008813:Mice, Inbred ICR; D020319:Oligodeoxyribonucleotides, Antisense / Q000008:administration & dosage* / Q000493:pharmacokinetics* / Q000627:therapeutic use; D010743:Phospholipids
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents; D002214:Capsules; D003470:Culture Media; D003902:Detergents; D004337:Drug Carriers; D008081:Liposomes; D020319:Oligodeoxyribonucleotides, Antisense; D010743:Phospholipids; D004139:Dinitrofluorobenzene