title: Assessment of facial nerve function in acoustic tumor disease by nasal muscle F waves and transcranial magnetic stimulation.
abstract: Standard transcranial magnetic stimulation and nasal muscle F-wave recordings were used to assess proximal facial nerve function in 27 patients with unilateral acoustic tumors (mean diameter, 29 mm) and clinically intact facial nerve function. Latency measurements for F waves and cortical magnetic stimulation were abnormal. Moreover, F ratios, central motor conduction time, and the ratio of response latency to cortical and cisternal magnetic stimulation were significantly increased. Amplitudes were unchanged. Correlation analysis with tumor diameter as dependent variable yielded maximum r values for F-wave latencies (0.57) and F ratios (0.41), whereas for magnetic stimulation, a significant correlation could be found (0.4) only for cortical stimulation. Nasal muscle F-wave recording can reveal clinically inapparent facial nerve dysfunction. Its efficacy in predicting tumor diameter seems to be superior to that of standard magnetic stimulation.
authors.affiliation: Department of Neurosurgery, University of Cologne, D-50924 Cologne, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Wedekind
authors.forename: N
authors.initials: N
authors.lastname: Klug
mesh_terms: D000328:Adult; D000368:Aged; D001767:Blinking / Q000502:physiology; D005154:Facial Nerve / Q000503:physiopathology*; D005260:Female; D006801:Humans; D015225:Magnetoencephalography; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000503:physiopathology*; D009296:Nasal Cavity / Q000502:physiology*; D009464:Neuroma, Acoustic / Q000473:pathology / Q000503:physiopathology*