Effects of pancreas transplantation on late complications of diabetes and metabolic effects of pancreas and islet transplantation.
Pancreas transplantation has become an accepted therapeutic approach to treat insulin-dependent diabetes mellitus, successfully restoring normoglycemia. In contrast, islet transplantation is still in the experimental phase, only a few operations having being performed world-wide. The aim of this review is to analyze the effects of pancreas transplantation on the late complications of diabetes and to report the endocrino-metabolic effects of pancreas and islet transplantation.
Caldara
R
R
Scientific Institute H. San Raffaele, Milan, Italy.
La Rocca
E
E
Maffi
P
P
Secchi
A
A
D001786:Blood Glucose / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000378:metabolism / Q000601:surgery*; D006801:Humans; D007328:Insulin / Q000097:blood; D016381:Islets of Langerhans Transplantation; D016035:Pancreas Transplantation
D001786:Blood Glucose; D007328:Insulin