title: Three dimensional (3D) analysis of the morphological changes induced by 50 Hz magnetic field exposure on human lymphoblastoid cells (Raji).
abstract: Human Raji B lymphoid cells after exposure for 64 h to a 1 mT (rms) 50 Hz sinusoidal magnetic field showed a reorganization of membrane and cytoskeletal components. Atomic force microscopy in air revealed several modifications in 80% of the exposed cells, such as loss of microvilli-like structures followed by progressive appearance of membrane introflections. This change in plasma membrane morphology was also accompanied by a different actin distribution, as detected by phalloidin fluorescence. These observations support our previous hypothesis that electric and magnetic fields may modify the plasma membrane structure.
authors.affiliation: Istituto di Medicina Sperimentale - CNR, Via Fosso del Cavaliere, Roma, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Lisi
authors.forename: D
authors.initials: D
authors.lastname: Pozzi
authors.forename: E
authors.initials: E
authors.lastname: Pasquali
authors.forename: S
authors.initials: S
authors.lastname: Rieti
authors.forename: M
authors.initials: M
authors.lastname: Girasole
authors.forename: A
authors.initials: A
authors.lastname: Cricenti
authors.forename: R
authors.initials: R
authors.lastname: Generosi
authors.forename: A L
authors.initials: AL
authors.lastname: Serafino
authors.forename: A
authors.initials: A
authors.lastname: Congiu-Castellano
authors.forename: G
authors.initials: G
authors.lastname: Ravagnan
authors.forename: L
authors.initials: L
authors.lastname: Giuliani
authors.forename: S
authors.initials: S
authors.lastname: Grimaldi
mesh_terms: D001402:B-Lymphocytes / Q000473:pathology / Q000528:radiation effects* / Q000648:ultrastructure; D002051:Burkitt Lymphoma; D002462:Cell Membrane / Q000528:radiation effects* / Q000648:ultrastructure; D003599:Cytoskeleton / Q000528:radiation effects* / Q000648:ultrastructure; D004574:Electromagnetic Fields; D006801:Humans; D018625:Microscopy, Atomic Force / Q000379:methods; D018613:Microscopy, Confocal / Q000379:methods; D014407:Tumor Cells, Cultured