title: [Adverse effects of drugs in intensive care units: analysis of the administration of electrolyte solutions and antibiotics].
abstract: The aims of this study were: 1) to verify the incidence of adverse occurrences (AOs) with medication related to the time of electrolyte solutions infusion and the frequency of doses of antibiotics prescribed and administered to the patients; 2) to characterize the nature of those occurrences. The study was developed in two ICUs of a general hospital of São Paulo City. The population was composed by 51 patients that were in the ICUs in August of 1996. Sixty percent of the patients were older than 60 years, 58.8% were women, 49.1% remained in ICU from 1 to 4 days and 41.2% went to the Intermediate Care Units after ICU. Regarding the incidence of AOs related to the time of administration of the electrolyte solutions and the frequency of doses of antibiotics the non execution of the patient's medical prescriptions was verified in 76.3% and 38.8% respectively. The largest frequency of irregularities with the electrolyte solutions (60.2%) was the infusion faster than the prescribed time followed by the reduction of the number of doses of antibiotics administered. Taking these into consideration we have to invest in preventive measures to reduce those occurrences.
authors.affiliation: Bolsista PIBIC/CNPq.
authors.forename: S
authors.initials: S
authors.lastname: Manenti
authors.forename: A B
authors.initials: AB
authors.lastname: Chaves
authors.forename: R S
authors.initials: RS
authors.lastname: Leopoldino
authors.forename: K G
authors.initials: KG
authors.lastname: Padilha
mesh_terms: D000328:Adult; D016907:Adverse Drug Reaction Reporting Systems; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D001938:Brazil; D004573:Electrolytes / Q000009:adverse effects*; D005260:Female; D006769:Hospitals, General; D006779:Hospitals, Public; D006801:Humans; D015994:Incidence; D007262:Infusions, Intravenous / Q000009:adverse effects*; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008508:Medication Errors / Q000517:prevention & control / Q000706:statistics & numerical data*; D008875:Middle Aged; D011785:Quality Assurance, Health Care; D012189:Retrospective Studies; D012308:Risk Management; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D004573:Electrolytes