Hypothalamic control of feeding.
Our understanding of the hypothalamic control of energy homeostasis has increased greatly since the discovery of leptin, the adipose cell derived protein. Recent studies have identified several new hypothalamic neuropeptides that affect food intake and energy balance. By studying these molecules and their neuronal systems, receptors and interactions, we are beginning to unravel the circuitry between peripheral adipogenic signals and hypothalamic effector pathways.
Lawrence
C B
CB
School of Biological Sciences, University of Manchester, Manchester, M13 9PT, UK.
Turnbull
A V
AV
Rothwell
N J
NJ
D000818:Animals; D004435:Eating / Q000502:physiology*; D007031:Hypothalamus / Q000502:physiology*; D009419:Nerve Tissue Proteins / Q000502:physiology; D009479:Neuropeptides / Q000502:physiology; D018043:Receptors, Corticotropin / Q000502:physiology; D044101:Receptors, Melanocortin; D000521:alpha-MSH / Q000502:physiology; D000098882:Cocaine- and Amphetamine-Regulated Transcript Protein
D009419:Nerve Tissue Proteins; D009479:Neuropeptides; D018043:Receptors, Corticotropin; D044101:Receptors, Melanocortin; D000098882:Cocaine- and Amphetamine-Regulated Transcript Protein; D000521:alpha-MSH