title: Moxidectin pour-on for control of natural populations of the cattle tick Boophilus microplus (Acarina: Ixodidae).
abstract: Fifty Bos taurus x Bos indicus heifers naturally infested with Boophilus microplus ticks were divided into two groups of 25 heifers each. Individuals of one group were treated with moxidectin 0.5% pour-on at a dosage of 500 microg of moxidectin/kg body weight and heifers from the other group remained as untreated controls. An efficacy higher than 95% was found on days 7-21 after treatment by using female ticks 4.5-8.0 mm long as the main infestation parameter. A lower, but significant efficacy (p < 0.05) was also found on days 1 (32.3% efficacy) and 27 (73.4% efficacy) post-treatment. Significantly (p < 0.05) lower numbers of immature ticks were also observed on heifers of the treated group from days 7 through 27 after treatment. A lower engorgement weight of female ticks from treated heifers was found on days 1 and 21 after treatment. Treatment also affected reproductive performance (oviposition, egg hatch and number of eggs laid) of female ticks collected on Day 1.
authors.affiliation: Instituto Nacional de Tecnología Agropecuaria, Estación Experimental Agropecuaria Rafaela, Santa Fe, Argentina. aguglielmone@inta.gov.ar
authors.forename: A A
authors.initials: AA
authors.lastname: Guglielmone
authors.forename: A J
authors.initials: AJ
authors.lastname: Mangold
authors.forename: M E
authors.initials: ME
authors.lastname: Muñoz Cobeñas
authors.forename: N
authors.initials: N
authors.lastname: Scherling
authors.forename: F
authors.initials: F
authors.lastname: García Posse
authors.forename: O S
authors.initials: OS
authors.lastname: Anziani
authors.forename: M
authors.initials: M
authors.lastname: Ioppolo
mesh_terms: D000287:Administration, Topical; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D001118:Argentina; D002417:Cattle; D002418:Cattle Diseases / Q000469:parasitology / Q000517:prevention & control*; D005260:Female; D007306:Insecticides / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D018942:Macrolides; D010058:Oviposition / Q000187:drug effects; D013984:Tick Infestations / Q000517:prevention & control / Q000662:veterinary*; D013987:Ticks / Q000187:drug effects* / Q000502:physiology
chemical_list: D000900:Anti-Bacterial Agents; D007306:Insecticides; D018942:Macrolides; C027837:moxidectin