title: [The oxidative metabolic activity of the polymorphonuclear neutrophilic leukocytes in patients infected with the human immunodeficiency virus].
abstract: BACKGROUND
  Contradictory results on oxidative burst activity in HIV infection have been reported in the literature.
  
  
  METHODS
  Neutrophil oxidative metabolism was evaluated in 160 HIV-infected patients, by measuring the intracellular production of rhodamine.
  
  
  RESULTS
  Neutrophil oxidative metabolism was decreased. This impairment was related to viral load, CD4+ lymphocyte counts, neutrophil counts and therapy.
  
  
  CONCLUSIONS
  In HIV-infected patients, neutrophil oxidative metabolic activity decreases with disease progression. This may contribute to secondary opportunistic infections.
authors.affiliation: Facultad de Medicina y Odontología, Universidad de Santiago de Compostela, Vigo. pdiz@usc.es
authors.forename: P
authors.initials: P
authors.lastname: Diz Dios
authors.forename: A
authors.initials: A
authors.lastname: Ocampo Hermida
authors.forename: N
authors.initials: N
authors.lastname: Rayo Llerena
authors.forename: I
authors.initials: I
authors.lastname: Otero Varela
authors.forename: I
authors.initials: I
authors.lastname: Iglesias Martín
authors.forename: C
authors.initials: C
authors.lastname: Martínez Vázquez
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D005260:Female; D005434:Flow Cytometry / Q000706:statistics & numerical data; D015658:HIV Infections / Q000097:blood*; D015497:HIV-1; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000378:metabolism*; D010084:Oxidation-Reduction; D011897:Random Allocation