[Formation of dipeptides--a side reaction in racemization of phenylalanine].
It was shown that acetylated dipeptides, Ac-D-Phe-D-Phe-OH, Ac-L-Phe-L-Phe-OH, Ac-D-Phe-L-Phe-OH, and Ac-L-Phe-D-Phe-OH, are formed during D-phenylalanine racemization. The overall content of these dipeptides in the reaction mixture ranged from 40 to 60% depending on the reaction conditions. We concluded that, like alpha-aminoisobutyric acid, phenylalanine is prone to polymerization under racemization conditions.
Kotlova
E K
EK
State Research Institute of Genetics and Selection of Industrial Microorganisms, Moscow, Russia. lab11@vnigen.msk.su
Timokhina
E A
EA
Chestukhina
G G
GG
Stepanov
V M
VM
D002851:Chromatography, High Pressure Liquid; D013058:Mass Spectrometry; D010649:Phenylalanine / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D010649:Phenylalanine