title: Gallbladder ejection fraction: correlation of scintigraphic and ultrasonographic techniques.
abstract: OBJECTIVE
  The assessment of gallbladder function and ejection fraction using sincalide-enhanced biliary scintigraphy is a useful way to evaluate patients with recurrent right upper quadrant pain but no gallstones.
  
  
  METHODS
  We wanted to determine whether gallbladder contraction measured by ultrasonography could be used in place of biliary scintigraphy. Biliary scans with an infusion of sincalide and concurrent ultrasonography were performed in 17 patients with histories of recurrent abdominal pain and no evidence of gallstones by ultrasound.
  
  
  RESULTS
  Gallbladder ejection fractions calculated by ultrasound and scintigraphy using standard techniques showed only a weak correlation. The poor performance of ultrasound appears to arise because the variable shape of the gallbladder invalidates the calculation of its volume by the formula for a prolate spheroid. When gallbladders that were ellipsoidal were subselected, correlation was improved. The level of training of the sonologist did not have a significant effect on the results.
  
  
  CONCLUSIONS
  Gallbladder ejection fraction calculated by ultrasonography cannot be used routinely as a substitute for biliary scintigraphy.
authors.affiliation: Department of Radiology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA. alan.h.siegel@hitchcock.org
authors.forename: A
authors.initials: A
authors.lastname: Siegel
authors.forename: J C
authors.initials: JC
authors.lastname: Kuhn
authors.forename: H
authors.initials: H
authors.lastname: Crow
authors.forename: S
authors.initials: S
authors.lastname: Holtzman
mesh_terms: D015746:Abdominal Pain / Q000000981:diagnostic imaging / Q000209:etiology; D000293:Adolescent; D000328:Adult; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012044:Regression Analysis; D012844:Sincalide; D014463:Ultrasonography
chemical_list: D012844:Sincalide