title: [Apraxia of eyelid closure in a patient with progressive supranuclear palsy].
abstract: We reported a 68-year-old man with progressive supranuclear palsy who present with apraxia of eyelid closure. He showed horizontal and vertical supranuclear ophthalmoplegia, neck dystonic posture, pseudobulbar palsy and subcortical dementia. He opened his eyes almost all day long except for sleeping. His spontaneous blinking was noted at less than 1 per a minute. Although he closed his eyes reflexively, he could not close his eyes by verbal command. He occasionally closed his eyelids by using both hands. The surface electromyographic (EMG) findings revealed that the frequency of frontal muscle contraction did not decrease, and rather increased during verbal command to close his eyes. The contraction frequency of orbicularis oculi muscle did not increase by the command of voluntary eyelid closure. It is suggested that abnormal contractions of frontalis and orbicularis oculi muscles which are correlated in eyelid closing and opening might contribute to the apraxia of eyelid closure.
authors.affiliation: Department of Neurology, Kanazawa Medical University, Ishikawa-ken.
authors.forename: Y
authors.initials: Y
authors.lastname: Yamaya
authors.forename: A
authors.initials: A
authors.lastname: Yoshioka
authors.forename: T
authors.initials: T
authors.lastname: Shirakawa
authors.forename: G
authors.initials: G
authors.lastname: Hirose
mesh_terms: D000368:Aged; D020240:Apraxia, Ideomotor / Q000209:etiology*; D004576:Electromyography; D005143:Eyelids; D006801:Humans; D008297:Male; D013494:Supranuclear Palsy, Progressive / Q000150:complications*