[Functional loading tests in nephropathy examination in patients recovering from hemorrhagic fever with renal syndrome].
OBJECTIVE
To characterize nephropathy in patients recovering after hemorrhagic fever with renal syndrome (HFRS) using functional loading tests.


METHODS
In 65 HFRS convalescents we examined renal function under water deprivation, exercises and studied intraglomerular hemodynamics.


RESULTS
After 2-month follow-up renal functional reserve was absent in 34% of the convalescents indicating intraglomerular hypertension. Under water deprivation most of the patients showed persistent tubulointerstitial disorders. Submaximal muscular exercises aggravated glomerular and tubular dysfunction manifesting with microalbuminuria, increased excretory beta 2-microglobulin fraction, low concentration reserve.


CONCLUSIONS
Functional loading tests provide more detailed characterization of renal function in HFRS convalescents.
Pimenov
L T
LT
Dudarev
M V
MV
Kustarnikov
G K
GK
D000419:Albuminuria / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000652:urine; D005080:Exercise Test; D005919:Glomerular Filtration Rate; D006480:Hemorrhagic Fever with Renal Syndrome / Q000150:complications*; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology / Q000652:urine; D001613:beta 2-Microglobulin / Q000652:urine
D001613:beta 2-Microglobulin