Congenital taillessness in AGUS inbred rats.
From a survey of breeding records of the AGUS/ Lac rat colony, 1% of animals weaned were found to lack tails. Post-mortem examination of 5 females showed major skeletal and genital abnormalities. Tailless rats were found more often than expected in 4th and 5th litters. A 'threshold' model of inheritance was postulated with an unknown environmental factor 'triggering' the condition.
Lovell
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MRC Experimental Embryology and Teratology Unit, Carshalton, Surrey, United Kingdom.
Sparrow
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D000818:Animals; D001947:Breeding; D005260:Female; D005836:Genitalia, Female / Q000002:abnormalities; D005856:Germ-Free Life; D015994:Incidence; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains / Q000002:abnormalities* / Q000235:genetics; D013623:Tail / Q000002:abnormalities*