title: Invasive disease due to extended spectrum beta-lactamase-producing Klebsiella pneumoniae in a neonatal unit: the possible role of cockroaches.
abstract: We recently experienced an outbreak of nosocomial disease due to extended spectrum beta-lactamase-producing Klebsiella pneumoniae in a neonatal unit infested with cockroaches. Organisms isolated from cockroaches were indistinguishable by pulsed-field gel electrophoresis from those colonizing infants or causing clinical disease using. Cockroach elimination together with standard infection-control measures resulted in control of the outbreak. We suggest cockroaches are possible vectors of pathogenic bacteria in the hospital environment.
authors.affiliation: Departments of Paediatrics and Child Health, University of Stellenbosch and Tygerberg Hospital, 7505, South Africa.
authors.forename: M F
authors.initials: MF
authors.lastname: Cotton
authors.forename: E
authors.initials: E
authors.lastname: Wasserman
authors.forename: C H
authors.initials: CH
authors.lastname: Pieper
authors.forename: D C
authors.initials: DC
authors.lastname: Theron
authors.forename: D
authors.initials: D
authors.lastname: van Tubbergh
authors.forename: G
authors.initials: G
authors.lastname: Campbell
authors.forename: F C
authors.initials: FC
authors.lastname: Fang
authors.forename: a J
authors.initials: aJ
authors.lastname: Barnes
mesh_terms: D000818:Animals; D003058:Cockroaches / Q000382:microbiology*; D003428:Cross Infection / Q000382:microbiology* / Q000635:transmission; D016521:Electrophoresis, Gel, Pulsed-Field / Q000379:methods; D006801:Humans; D007231:Infant, Newborn; D007303:Insect Vectors / Q000382:microbiology*; D007710:Klebsiella Infections / Q000382:microbiology* / Q000635:transmission; D007711:Klebsiella pneumoniae / Q000201:enzymology / Q000302:isolation & purification*; D009725:Nurseries, Hospital; D012189:Retrospective Studies; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D001618:beta-Lactamases