title: Wear of gamma-crosslinked polyethylene acetabular cups against roughened femoral balls.
abstract: Crosslinking of ultrahigh molecular weight polyethylene has been shown to markedly improve its wear resistance in clinical studies and laboratory tests using hip joint simulators. However, because most of the laboratory studies have been done under clean conditions using prosthesis-quality, highly polished counterfaces, there is concern regarding how well an intentionally crosslinked polyethylene acetabular cup will resist abrasion by a femoral ball that has been damaged by third-body abrasion in vivo. To investigate this, conventional and radiation crosslinked-remelted acetabular cups of ultra-high molecular weight polyethylene were tested in a hip joint simulator bearing against smooth femoral balls and against balls with moderate and severe roughening. Cups were tested with and without aging to accelerate any oxidative degradation. The crosslinked cups were produced by exposing extruded GUR 4150 bar stock of ultrahigh molecular weight polyethylene to 5 Mrad gamma radiation under a partial vacuum and then the bars were remelted to extinguish residual free radicals. Artificial aging at 70 degrees C under 5 atm oxygen for 14 days induced negligible oxidation in the crosslinked and remelted material. Against smooth balls, the wear of the crosslinked cups, with or without aging, averaged approximately 15% of that of the conventional cups. Against the moderately rough balls, the wear rate of the conventional cups was unchanged, whereas the wear rate increased slightly for the nonaged and aged crosslinked cups, but was still only 26% and 20% of that of the conventional cups, respectively. Against extremely rough balls, the mean wear rates increased markedly for each material such that during the final 1 million cycle interval, the average wear rates of the nonaged and the aged crosslinked cups were 72% and 47% of that of the conventional cups, respectively. That is, the crosslinked polyethylene showed substantially better wear resistance than conventional polyethylene across the range of ball roughnesses, with or without accelerated aging.
authors.affiliation: J. Vernon Luck Orthopaedic Research Center, Orthopaedic Hospital, Los Angeles, CA, USA.
authors.forename: H
authors.initials: H
authors.lastname: McKellop
authors.forename: F W
authors.initials: FW
authors.lastname: Shen
authors.forename: W
authors.initials: W
authors.lastname: DiMaio
authors.forename: J G
authors.initials: JG
authors.lastname: Lancaster
mesh_terms: D000077:Acetabulum; D019544:Equipment Failure Analysis / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D005270:Femur Head; D005720:Gamma Rays; D006622:Hip Prosthesis / Q000706:statistics & numerical data; D006358:Hot Temperature; D006801:Humans; D008970:Molecular Weight; D020959:Polyethylene / Q000737:chemistry / Q000528:radiation effects*; D011474:Prosthesis Design / Q000379:methods / Q000706:statistics & numerical data; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D013997:Time Factors
chemical_list: D020959:Polyethylene