[Therapy of osteoporosis: strategies for individualized treatment].
Pharmacological and non-pharmacological interventions are available and useful for effective treatment of osteoporosis. Drugs act by stimulation of bone formation (fluoride) or inhibition of bone resorption (calcium, vitamin D compounds, bisphosphonates, hormone replacement therapy, calcitonin). Published data for effectiveness on bone mineral density and/or fracture rates vary considerably. Non-pharmacological interventions to prevent falls or the impact of falls (hip protectors) must be part of a sufficient treatment strategy. Costs of treatment have to be considered in comparison to costs of fracture repair and rehabilitation.
Weber
K
K
Klinischen Abteilung für Endokrinologie und Nuklearmedizin, Medizinischen Universitätsklinik Graz. kurt.weber@kfunigraz.ac.at
Hoffmann
A
A
Leb
G
G
D000058:Accidental Falls / Q000517:prevention & control*; D001317:Austria; D002116:Calcitonin / Q000627:therapeutic use; D002117:Calcitriol / Q000627:therapeutic use; D002118:Calcium / Q000627:therapeutic use; D002120:Calcium Channel Agonists / Q000627:therapeutic use; D004164:Diphosphonates / Q000627:therapeutic use; D015914:Estrogen Replacement Therapy; D005459:Fluorides / Q000627:therapeutic use; D050723:Fractures, Bone / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D010024:Osteoporosis / Q000188:drug therapy* / Q000191:economics / Q000517:prevention & control*; D014807:Vitamin D / Q000627:therapeutic use
D002120:Calcium Channel Agonists; D004164:Diphosphonates; D014807:Vitamin D; D002116:Calcitonin; D002117:Calcitriol; D005459:Fluorides; D002118:Calcium