title: Antimalarials from Stephania venosa, Prismatomeris sessiliflora, Diospyros montana and Murraya siamensis.
abstract: Fourteen compounds isolated from Stephania venosa, Prismatomeris sessiliflora, Diospyros montana and Murraya siamensis were tested for their antimalarial potential. The 6a,7-dehydroaporphine alkaloids dehydrostephanine and dehydrocrebanine showed potent activity with IC50 values of 40 and 70 ng/ml, respectively. The 13C-NMR data of rubiadin, rubiadin-1-methyl ether, diospyrin and 5-hydroxy-4-methoxy-2-naphthal-dehyde were extensively studied.
authors.forename: K
authors.initials: K
authors.lastname: Likhitwitayawuid
authors.forename: S
authors.initials: S
authors.lastname: Dej-adisai
authors.forename: V
authors.initials: V
authors.lastname: Jongbunprasert
authors.forename: J
authors.initials: J
authors.lastname: Krungkrai
mesh_terms: D000962:Antimalarials / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000962:Antimalarials