Concordance of primary generalised epilepsy and carbamazepine hypersensitivity in monozygotic twins.
In this paper we describe the previously unreported phenomenon of a carbamazepine-induced mucocutaneous syndrome in identical twins. These twins had developed primary generalised epilepsy within 2 months of each other.
Edwards
S G
SG
Department of Clinical Neurology, St Mary's Hospital, Paddington, London, UK.
Hubbard
V
V
Aylett
S
S
Wren
D
D
D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D002220:Carbamazepine / Q000009:adverse effects* / Q000627:therapeutic use; D004200:Diseases in Twins; D003875:Drug Eruptions / Q000235:genetics* / Q000473:pathology; D004569:Electroencephalography; D004829:Epilepsy, Generalized / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male; D014430:Twins, Monozygotic
D000927:Anticonvulsants; D002220:Carbamazepine