title: The 1951-98 experience of the Paris Institut Curie Radiopathology Unit: a preliminary report.
abstract: From 1 January 1951 to 30 June 1998, 696 patients presented spontaneously or were referred to the French Institut Curie Radiopathology Unit following a more or less severe accidental irradiation. Of these, 568 patients came from France, while 128 were sent by various foreign countries. The very great majority of irradiation accidents occurred in the workplace, particularly in industry. Interestingly, 'non-nuclear' industry was responsible for three times more events than the nuclear industry. While incidental irradiation of the public by lost radioactive sources was exceedingly rare in France, it seemed to be more frequent in our cohort of foreign patients. Radiation phobia accounted for about 10% of cases in the French cohort, but the number of cases did not seem to increase with time. Overall, the accrual of patients over time appears to be stable, with 10 to 25 new cases consulting each year. Fortunately, a majority of cases corresponded to low-level irradiation (and even no irradiation at all). In the French cohort, only 21.6% of patients, showing deterministic effects, required some form of treatment, with 4.9% considered as 'severe' cases. Not unexpectedly, more patients required treatment in the foreign cohort (35.2%), with 24.2% of severe cases, including four deaths. The main features of this database are consistent with the data previously reported by the IAEA, UNSCEAR and REAC/TS. Although the number of severe cases is small, it should still be considered to be too high, especially as most of these accidents could have been easily avoided if a few basic radioprotection rules had been fully respected.
authors.affiliation: Institut Curie, Paris, France.
authors.forename: J M
authors.initials: JM
authors.lastname: Cosset
authors.forename: B
authors.initials: B
authors.lastname: Perdereau
authors.forename: B
authors.initials: B
authors.lastname: Dubray
authors.forename: S
authors.initials: S
authors.lastname: Helfre
authors.forename: F
authors.initials: F
authors.lastname: Brixy
authors.forename: R
authors.initials: R
authors.lastname: Gongora
authors.forename: A
authors.initials: A
authors.lastname: Fourquet
mesh_terms: D000062:Accidents, Occupational / Q000145:classification / Q000517:prevention & control / Q000706:statistics & numerical data; D002423:Cause of Death; D015331:Cohort Studies; D019992:Databases as Topic; D005060:Europe / Q000453:epidemiology; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D010297:Paris; D010698:Phobic Disorders / Q000628:therapy; D011829:Radiation Dosage; D011830:Radiation Effects; D011835:Radiation Protection; D018788:Radioactive Hazard Release / Q000145:classification / Q000517:prevention & control / Q000706:statistics & numerical data*; D011850:Radioactive Waste / Q000009:adverse effects; D011868:Radioisotopes / Q000009:adverse effects; D011872:Radiology Department, Hospital / Q000706:statistics & numerical data; D012042:Registries; D012189:Retrospective Studies
chemical_list: D011850:Radioactive Waste; D011868:Radioisotopes