Use of solid-phase microextraction for the analysis of bisphenol A and bisphenol A diglycidyl ether in food simulants.
A new method has been developed to simultaneously analyse bisphenol A (BPA) and bisphenol A diglycidyl ether (BADGE) in aqueous based food simulants. The method consists on direct immersion solid-phase microextraction (SPME) of the analytes from the liquid matrix and subsequent chromatographic analysis by gas chromatography-mass spectrometry. Using the proposed method, a whole analysis (including chromatographic step) can be completed in less than 40 min, with minimum sample handling. The SPME method shows good analytical performance for simultaneous BPA and BADGE analysis, except for BADGE determination in the aqueous alcohol (simulant C) solution. Detection limits ranging from 0.1 to 2.0 ng/g for BPA and from 13 to 15 ng/g from BADGE were obtained, with a linear range from the low-ng/g to several-microg/g range for BPA and from 0.1 microg/g to 40 microg/g for BADGE. A possible optimisation method has been also developed and introduced.
Salafranca
J
J
Department of Analytical Chemistry, CPS-University of Zaragoza, Spain.
Batlle
R
R
Nerín
C
C
D001559:Benzhydryl Compounds; D002273:Carcinogens / Q000032:analysis*; D004852:Epoxy Compounds / Q000032:analysis*; D000431:Ethanol; D005504:Food Analysis / Q000379:methods*; D005506:Food Contamination; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D010636:Phenols / Q000032:analysis*; D012680:Sensitivity and Specificity; D012995:Solubility; D012996:Solutions; D000098826:Bisphenol A Compounds
D001559:Benzhydryl Compounds; D002273:Carcinogens; D004852:Epoxy Compounds; D000431:Ethanol; D010636:Phenols; D012996:Solutions; C019273:bisphenol A diglycidyl ether; D000098826:Bisphenol A Compounds; C006780:bisphenol A