[Unusual site of an embryonal rhabdomyosarcoma of the mesenchymal hepatic pedicle].
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of children. Tumors arising in the extrahepatic biliary tree are extremely rare (less than 1% of cases). In this location, most are RMS of the botryoid type. We report a case of a 10-year-old child with embryonal RMS arising in the mesenchyma of the hepatic pedicle. Most tumor cells were large, round with abundant eosinophilic cytoplasm. A few cells were small round or spindle-shaped. Tumor cells showed positive immunostaining for muscle markers: desmin and sarcomeric actin. Electron microscopy revealed 2 types of cells: some were undifferentiated and others showed striated muscle differentiation features.
Ferlicot
S
S
Anatomie et Cytologie Pathologiques, CHU de Bicêtre, Le Kremlin-Bicêtre.
Quillard
J
J
Chardot
C
C
Caillou
B
B
Oberlin
O
O
Gauthier
F
F
Fabre
M
M
D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D008297:Male; D008648:Mesoderm; D018233:Rhabdomyosarcoma, Embryonal / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure