Isolation, characterization, and chromosomal location of the mouse enamelysin gene.
Mouse enamelysin (Mmp20), a member of the matrix metalloproteinase (MMP) family of extracellular matrix degrading enzymes, shows a high degree of homology with other MMPs, particularly those of the stromelysin/collagenase subfamilies. It is expressed exclusively in ameloblasts and odontoblasts. The mouse enamelysin gene (Mmp20) is made up of 10 exons spanning approximately 65 kb within the MMP gene cluster at the centromeric end of chromosome 9.
Caterina
J
J
National Institute of Dental and Craniofacial Research, Bethesda, Maryland 20892, USA. jc239h@nih.gov
Shi
J
J
Krakora
S
S
Bartlett
J D
JD
Engler
J A
JA
Kozak
C A
CA
Birkedal-Hansen
H
H
D000818:Animals; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D017931:DNA Primers / Q000737:chemistry; D005091:Exons / Q000235:genetics; D005786:Gene Expression Regulation; D005819:Genetic Markers; D007438:Introns / Q000235:genetics; D053519:Matrix Metalloproteinase 20; D020782:Matrix Metalloproteinases / Q000096:biosynthesis / Q000737:chemistry* / Q000235:genetics* / Q000302:isolation & purification; D051379:Mice; D008810:Mice, Inbred C57BL; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics; D009115:Muridae
D017931:DNA Primers; D005819:Genetic Markers; D053519:Matrix Metalloproteinase 20; D020782:Matrix Metalloproteinases; C507113:Mmp20 protein, mouse