Antibacterial activity of Orobanche cernua extract.
The effect of the parasitic plant Orobanche cernua extract was evaluated on 5 different Gram-positive and Gram-negative bacteria. Dilution experiments show that the minimum inhibitory concentration (MIC; microgram/ml) of the extract was as follows: Staphylococcus aureus-1526.5; Streptococcus sp.-3125; Streptococcus pyogenes-25,000 and both for Bacillus cereus and Escherichia coli-50,000 micrograms/ml. Data indicated that the MIC of 3125 micrograms/ml is equal to cefotaxime (30 micrograms) and tobromycin (10 micrograms) activity against Streptococcus sp. and S. aureus, respectively; 25,000 and 50,000 micrograms/ml is equal to cefotaxime (30 micrograms) activity against S. pyogenes and B. cereus, respectively, and 50,000 micrograms/ml is equal to nalidixic acid (30 micrograms) activity against E. coli. It can be concluded that the O. cernua extract displays remarkable activity against some Gram-positive bacteria such as Streptococcus and Staphylococcus.
Saadoun
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Department of Applied Biology, Jordan University of Science and Technology, Irbid, Jordan. isaadoun@just.edu.jo
Hameed
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KM
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000898:Antibiosis; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D019684:Magnoliopsida; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D010936:Plant Extracts