[Prognosis of individual survival in animals with fatal and non-fatal tumors].
Cohort analysis of life span in a uniform LIO rat population established a correlation between death cause and age-related death force parameters. It also demonstrated certain sex-related differences involved. The life span of males which had tumors at the time of death, whatever the real cause of death, was significantly longer than that in tumor-free animals. The life span of tumor-free females and those which died from cancer was shorter while the longest-surviving group bore non-fatal tumors. It is suggested that prognosis of individual survival be based on a combination of traditional procedures of mathematical evaluation of population mortality rates and complex assessment of individual health. This approach envisages formation of cohorts characterized by maximum differences in aging dynamics.
Krut'ko
V N
VN
Institute for Systems Analysis, Russian Academy of Sciences, Moscow.
Smirnova
T M
TM
Anisimov
V N
VN
D000375:Aging; D000818:Animals; D002423:Cause of Death; D005260:Female; D008297:Male; D008962:Models, Theoretical; D009374:Neoplasms, Experimental; D011379:Prognosis; D017678:Sex Distribution; D016019:Survival Analysis