title: Squamous cell carcinoma of the tongue in young adults: increasing incidence and factors that predict treatment outcomes.
abstract: OBJECTIVE
  This study was designed to determine whether the incidence of squamous cell carcinoma of the oral tongue (SCCOT) in young adults has changed during the past 25 years and to determine prognostic factors for young adult patients (aged < 40 years) with SCCOT.
  
  
  METHODS
  A retrospective review of young adults with SCCOT who sought treatment at the M. D. Anderson Cancer Center between 1973 and 1995 was undertaken.
  
  
  RESULTS
  The percentage of young adult SCCOT patients at M. D. Anderson increased from 4% in 1971 to 18% in 1993. T stage, N stage, perineural invasion, and lymphatic invasion were all associated with decreased survival. Patients who received a neck dissection as part of their primary treatment had a better chance of survival than patients who did not.
  
  
  CONCLUSIONS
  The incidence of SCCOT in the young adult population is increasing in the United States. Appropriate surgical management for young adults with SCCOT includes resection of the primary tumor along with a selective node dissection.
authors.affiliation: Department of Head and Neck Surgery, University of Texas M. D. Anderson Cancer Center, Houston, USA.
authors.forename: J N
authors.initials: JN
authors.lastname: Myers
authors.forename: T
authors.initials: T
authors.lastname: Elkins
authors.forename: D
authors.initials: D
authors.lastname: Roberts
authors.forename: R M
authors.initials: RM
authors.lastname: Byers
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D014062:Tongue Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D014481:United States / Q000453:epidemiology