Stimulation of nonspecific resistance by thymopentin and its analogs against Leishmania donovani infection in hamsters.
Thymopentin and its analogs have been synthesized by the solution phase method of peptide synthesis and evaluated for their prophylactic efficacy against L. donovani infection in hamsters. Thymopentin and some of the analogs were found to stimulate nonspecific resistance of the host against Leishmania donovani infection in hamsters.
Sharma
P
P
Division of Parasitology, Central Drug Research Institute, Lucknow, India.
Anuradha
Rohatgi
A
A
Haq
W
W
Mathur
K B
KB
Katiyar
J C
JC
D000818:Animals; D006224:Cricetinae; D004305:Dose-Response Relationship, Drug; D007893:Leishmania donovani / Q000302:isolation & purification*; D007896:Leishmaniasis / Q000469:parasitology / Q000517:prevention & control*; D016305:Thymopentin / Q000031:analogs & derivatives / Q000627:therapeutic use*
D016305:Thymopentin