title: Analysis of X-ray-induced aberrations in human chromosome 5 using high-resolution multicolour banding FISH (mBAND).
abstract: Peripheral lymphocytes were exposed to 4 Gy X-rays and aberrations were analysed in human chromosome 5 using high-resolution multicolour banding fluorescence in-situ hybridization (mBAND). This method is suited to detect simple and complex aberrations including peri- and paracentric inversions and exchanges between both chromosomes 5. Additionally, breakpoints carr be assigned to specific regions in chromosome 5. Quantitative relationships of induced aberration types are discussed.
authors.affiliation: Department of Genetics, Universität GH Essen, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Johannes
authors.forename: I
authors.initials: I
authors.lastname: Chudoba
authors.forename: G
authors.initials: G
authors.lastname: Obe
mesh_terms: D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002895:Chromosomes, Human, Pair 5; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D066298:In Vitro Techniques; D008297:Male; D014965:X-Rays