Wolman's disease diagnosed by intestinal biopsy.
We describe a fatal case of Wolman's disease in a 5-month-old Italian infant with severe gastrointestinal symptoms in whom the diagnosis was made from intestinal biopsy findings at the age of 3 1/2 months. Abdominal CT scan, elevated blood acid phosphatase levels and histologic findings confirmed the diagnosis.
Castro
M
M
Department of Gastroenterology, Children's Hospital Bambino Gesù, Rome, Italy. castro@obg-irccs.rm.it
Rosati
P
P
Boldrini
R
R
Lucidi
V
V
Gambarara
M
M
Bosman
C
C
D001707:Biopsy, Needle; D018450:Disease Progression; D016145:Endoscopy, Digestive System; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D007413:Intestinal Mucosa / Q000473:pathology*; D008297:Male; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D015223:Wolman Disease / Q000175:diagnosis / Q000473:pathology*