title: The IL-2 receptor in hemocytes of the sea mussel Mytilus galloprovincialis Lmk.
abstract: In the hemolymph of the sea mussel Mytilus galloprovincialis, two different cell types have been found. Rounded (RH) cells display a nucleus that is very large in relation to the cell size; spread (SH) cells have an expanded cytoplasm and multiple granules. We determined by flow cytometry that only the SH cell types express three interleukin-2 receptor (IL-2R) subunits. Mussel IL-2R alpha and IL-2R beta subunits display a molecular weight similar to those in vertebrates tissues, whereas mussel IL-2R gamma is smaller than that in vertebrates. Both lipopolysaccharide and IL-2 induce IL-2R alpha expression, and such induction depends on the concentration of both agonists.
authors.affiliation: Departamento de Bioquímica y Biología Molecular, Universidad de Santiago de Compostela, Facultad de Veterinaria, Lugo, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Barcia
authors.forename: A
authors.initials: A
authors.lastname: Cao
authors.forename: J
authors.initials: J
authors.lastname: Arbeteta
authors.forename: J I
authors.initials: JI
authors.lastname: Ramos-Martinez
mesh_terms: D000818:Animals; D049872:Bivalvia / Q000378:metabolism*; D005434:Flow Cytometry; D006458:Hemolymph / Q000276:immunology / Q000378:metabolism*; D007376:Interleukin-2 / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000494:pharmacology; D008970:Molecular Weight; D015375:Receptors, Interleukin-2 / Q000819:agonists / Q000276:immunology / Q000378:metabolism*
chemical_list: D007376:Interleukin-2; D008070:Lipopolysaccharides; D015375:Receptors, Interleukin-2