title: [Functional loading tests in nephropathy examination in patients recovering from hemorrhagic fever with renal syndrome].
abstract: OBJECTIVE
  To characterize nephropathy in patients recovering after hemorrhagic fever with renal syndrome (HFRS) using functional loading tests.
  
  
  METHODS
  In 65 HFRS convalescents we examined renal function under water deprivation, exercises and studied intraglomerular hemodynamics.
  
  
  RESULTS
  After 2-month follow-up renal functional reserve was absent in 34% of the convalescents indicating intraglomerular hypertension. Under water deprivation most of the patients showed persistent tubulointerstitial disorders. Submaximal muscular exercises aggravated glomerular and tubular dysfunction manifesting with microalbuminuria, increased excretory beta 2-microglobulin fraction, low concentration reserve.
  
  
  CONCLUSIONS
  Functional loading tests provide more detailed characterization of renal function in HFRS convalescents.
authors.forename: L T
authors.initials: LT
authors.lastname: Pimenov
authors.forename: M V
authors.initials: MV
authors.lastname: Dudarev
authors.forename: G K
authors.initials: GK
authors.lastname: Kustarnikov
mesh_terms: D000419:Albuminuria / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000652:urine; D005080:Exercise Test; D005919:Glomerular Filtration Rate; D006480:Hemorrhagic Fever with Renal Syndrome / Q000150:complications*; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology / Q000652:urine; D001613:beta 2-Microglobulin / Q000652:urine
chemical_list: D001613:beta 2-Microglobulin