title: Mixed germ cell tumour of the pineal region: a case report.
abstract: An intracranial mixed germ cell tumour with germinoma and teratoma components is reported. The patient presented with parinaud's syndrome and precocious puberty. The treatment involved partial surgical debulking followed by whole brain radiotherapy (4500 cGY in 25 fraction over 5 weeks) and chemotherapy (consisting of cisplatin and etoposide). Post treatment MRI showed no residual lesion. The controversies in the management are discussed.
authors.affiliation: Departments of Radiotherapy and Oncology, Neurosurgery and Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
authors.forename: N
authors.initials: N
authors.lastname: Tandon
authors.forename: R
authors.initials: R
authors.lastname: Chopra
authors.forename: S
authors.initials: S
authors.lastname: Ghoshal
authors.forename: P
authors.initials: P
authors.lastname: Singh
authors.forename: B S
authors.initials: BS
authors.lastname: Sharma
mesh_terms: D000293:Adolescent; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005047:Etoposide / Q000627:therapeutic use; D018237:Germinoma / Q000188:drug therapy* / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D008297:Male; D010871:Pinealoma / Q000188:drug therapy* / Q000532:radiotherapy* / Q000601:surgery; D011838:Radiation-Sensitizing Agents / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D011838:Radiation-Sensitizing Agents; D005047:Etoposide; D002945:Cisplatin