title: [Initial manifestation of a manic syndrome in advanced age in subcortical arteriosclerotic encephalopathy (Binswanger disease)].
abstract: We describe the case of a 65-year old man who presented with a first episode of mania lacking a history of previous affective illness. Clinical, neuropsychological and NMR-findings pointed to a subcortical arteriosclerotic encephalopathy (Morbus Binswanger) as an underlying organic condition. According Kleman's concept of "secondary mania" this case illustrates the necessity a thorough search for organic conditions in late manifesting affective illness which may also involve therapeutic considerations.
authors.affiliation: Klinikum Erfurt.
authors.forename: C
authors.initials: C
authors.lastname: Hain
authors.forename: K
authors.initials: K
authors.lastname: Peter
mesh_terms: D000368:Aged; D001714:Bipolar Disorder / Q000175:diagnosis*; D001933:Brain Stem / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D003702:Delusions / Q000175:diagnosis; D015140:Dementia, Vascular / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004569:Electroencephalography; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D015899:Tomography, Emission-Computed, Single-Photon