title: Capillary blood flow velocity in patients with idiopathic epiretinal membranes.
abstract: OBJECTIVE
  Eyes with idiopathic epiretinal membranes (ERM) often have tortuous vessels and macular edema, suggesting that eyes with ERM may have a disturbance of the macular microcirculation. The authors studied perifoveal microcirculation in eyes with ERM by means of scanning laser ophthalmoscope (SLO) fluorescein angiography.
  
  
  METHODS
  Mean capillary blood flow velocity (CFV) was measured by SLO fluorescein angiography in 19 eyes with ERM before and 6 months after vitreous surgery and in 19 healthy control eyes.
  
  
  RESULTS
  Mean CFV was significantly reduced in the eyes with ERM compared with the healthy control eyes (2.98 +/- 0.32 mm/sec versus 3.34 +/- 0.12 mm/sec, P < 0.05), and postoperative mean CFV was significantly increased compared with preoperative mean CFV (3.14 +/- 0.32 mm/sec versus 2.98 +/- 0.32 mm/sec, P < 0.05).
  
  
  CONCLUSIONS
  Eyes with ERM show abnormal hemodynamics in the perifoveal capillaries. Surgical treatment of eyes with ERM results in improvement of the abnormal blood flow.
authors.affiliation: Department of Ophthalmology, Yokohama City University School of Medicine, Yokohama, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kadonosono
authors.forename: N
authors.initials: N
authors.lastname: Itoh
authors.forename: E
authors.initials: E
authors.lastname: Nomura
authors.forename: S
authors.initials: S
authors.lastname: Ohno
mesh_terms: D001783:Blood Flow Velocity; D002196:Capillaries / Q000503:physiopathology; D019773:Epiretinal Membrane / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007834:Lasers; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D012171:Retinal Vessels / Q000473:pathology / Q000503:physiopathology*; D012189:Retrospective Studies; D014821:Vitrectomy