title: Accuracy of ultrasonography and magnetic resonance imaging in detecting failure of breast implants filled with silicone gel.
abstract: We prospectively studied the accuracy of magnetic resonance imaging (MRI) and ultrasonography (US) for preoperative detection of rupture in 35 single-lumen implants filled with silicone gel in 18 patients. The positive predictive value of US for rupture of an implant was 70% and the negative predictive value 64%. Sensitivity and specificity were 44% and 87%, respectively. Accuracy, defined as the total true positive and true negative values divided by the total number of implants studied was 66%. The positive predictive value of MRI was 100% and the negative predictive value 90%. The corresponding sensitivity and specificity were 88% and 100% and the accuracy 94%. MRI offers significantly better diagnostic sensitivity (p = 0.02) and accuracy (p = 0.004), and should be regarded as the "gold standard" in the evaluation of rupture of breast implants filled with silicone gel. When MRI is not readily available, US is an acceptable alternative.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Academisch Ziekenhuis Vrije Universiteit, Amsterdam, The Netherlands.
authors.forename: W H
authors.initials: WH
authors.lastname: Beekman
authors.forename: J J
authors.initials: JJ
authors.lastname: Hage
authors.forename: A H
authors.initials: AH
authors.lastname: Taets van Amerongen
authors.forename: J W
authors.initials: JW
authors.lastname: Mulder
mesh_terms: D000328:Adult; D000368:Aged; D018427:Breast Implants; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011446:Prospective Studies; D011475:Prosthesis Failure; D012680:Sensitivity and Specificity; D020034:Silicone Gels; D014463:Ultrasonography
chemical_list: D020034:Silicone Gels