Angiomyolipoma of the large intestine: report of a case.
A case of an angiomyolipoma of the large intestine occurring in a 55-year-old man without evidence of tuberous sclerosis is reported. Endoscopically, the lesion resembled a sessile adenomatous polyp. The tumor measured 1 cm. Histologic examination revealed a lesion composed predominantly of spindle and epithelioid cells with significant nuclear atypia. Mitoses were rare. The tumor was strongly positive for HMB-45, CD68, vimentin, desmin, and smooth muscle actin. Rare scattered cells reacted with CD34. No residual tumor was found in the resected colon.
Maluf
H
H
Department of Pathology, Washington University School of Medicine, St. Louis, Missouri 63110-1093, USA. hmaluf@path.wustl.edu
Dieckgraefe
B
B
D000199:Actins / Q000378:metabolism; D000714:Anastomosis, Surgical; D018207:Angiomyolipoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D015703:Antigens, CD / Q000378:metabolism; D015214:Antigens, Differentiation, Myelomonocytic / Q000378:metabolism; D000951:Antigens, Neoplasm / Q000378:metabolism; D003082:Colectomy; D003110:Colonic Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D003893:Desmin / Q000378:metabolism; D006801:Humans; D008297:Male; D058950:Melanoma-Specific Antigens; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000378:metabolism; D014746:Vimentin / Q000378:metabolism; D000097382:CD68 Molecule
D000199:Actins; D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D000951:Antigens, Neoplasm; D003893:Desmin; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins; D014746:Vimentin; C067980:CD68 antigen, human; D000097382:CD68 Molecule