A retrospective study of late outcome in patients with peripheral arterial occlusive disease: an association between prosthetic vascular graft and cancer death?
The authors assessed the relationship between cause of death and treatment modality in patients with peripheral arterial occlusive disease. A total of 273 patients were treated with percutaneous transluminal angioplasty, surgical reconstruction, amputation, or medical therapy. We evaluated the outcome in various patient subgroups divided by treatments with a mean follow-up of 4.9 years. Most patients died because of cardiovascular or cerebrovascular events, and cancer was the second most frequent cause of death. Furthermore, there was a significant difference in cancer deaths between patients who received prosthetic vascular grafts and those with other types of treatment (9.3% vs. 2.8%, p<0.01, odds ratio = 3.34). It is noteworthy that patients with peripheral arterial occlusive disease succumbed to cancer, especially the patients with prosthetic vascular grafts.
Yoshitomi
Y
Y
Division of Cardiology, Tohsei National Hospital, Suntoh-gun, Shizuoka, Japan. yyoshito@jun.ncvc.go.jp
Kojima
S
S
Umemoto
T
T
Hosoi
Y
Y
Kuramochi
M
M
D000368:Aged; D000671:Amputation, Surgical; D017222:Angioplasty, Balloon, Laser-Assisted; D001157:Arterial Occlusive Diseases / Q000150:complications / Q000401:mortality* / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D002423:Cause of Death; D017023:Coronary Angiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications / Q000401:mortality; D016491:Peripheral Vascular Diseases / Q000150:complications / Q000401:mortality* / Q000601:surgery*; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome