Laryngeal manifestations of paracoccidioidomycosis (South American blastomycosis).
OBJECTIVE
To report clinical manifestations, diagnosis, and epidemiologic characteristics of laryngeal paracoccidioidomycosis.


METHODS
Case series.


METHODS
Tertiary care institutional hospital.


METHODS
We reviewed the hospital records of 7 patients with laryngeal paracoccidioidomycosis diagnosed by histopathological examination.


METHODS
Clinical manifestations of laryngeal paracoccidioidomycosis.


RESULTS
All patients were men and were middle-aged (range, 43-65 years), and most (86% [6/7]) were farm workers. All 7 patients regularly used tobacco, but only (43% [3/7]) were alcohol users. Clinical manifestations were dysphonia (86% [6/7]), dyspnea (71% [5/7]), dysphagia (43% [3/7]), and cough (29% [2/7]). Laryngeal examination revealed ulcerative lesions with a mulberrylike appearance in 3 patients and vegetative lesions in 4 patients. Many had multiple laryngeal lesions with involvement of the true and false vocal cords, the epiglottis, and the arytenoid and interarytenoid areas. The first diagnostic impression was carcinoma in all patients.


CONCLUSIONS
Laryngeal paracoccidioidomycosis may be a difficult diagnosis for the unsuspecting clinician to make. Examination of the larynx can reveal lesions similar to laryngeal cancer; therefore, diagnosis of carcinoma must be ruled out by histopathological examination or culture of a specimen.
Sant'Anna
G D
GD
Department of Otorhinolaryngology, Fundação Faculdade Federal de Ciências Médicas de Porto Alegre, Complexo Hospitalar Santa Casa, Brazil. gds@plug-in.com.br
Mauri
M
M
Arrarte
J L
JL
Camargo
H
H
D000328:Adult; D001938:Brazil / Q000453:epidemiology; D003937:Diagnosis, Differential; D006753:Hospital Records; D006801:Humans; D007828:Laryngoscopy; D007830:Larynx / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010229:Paracoccidioidomycosis / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology*