title: Surface micropatterning to regulate cell functions.
abstract: The current technology available for surface microfabrication with macromolecules to regulate cell functions is reviewed. Surface topology, and surface modification with hydrophilic or hydrophobic polymers, electrically charged polymers, stimuli-responsive macromolecules, polysaccharide, and proteins involving adhesion or growth factors are discussed. These surface-microfabricatec biomaterials had the ability to regulate cell functions such as proliferation, differentiation, and apoptosis.
authors.affiliation: Department of Biological Sciences and Technology, Faculty of Engineering, The University of Tokushima, Japan. ito@bio.tokushima-u.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Ito
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D001792:Blood Platelets / Q000378:metabolism; D016466:CHO Cells; D015815:Cell Adhesion Molecules / Q000494:pharmacology; D002460:Cell Line; D006224:Cricetinae; D005347:Fibroblasts / Q000378:metabolism; D006133:Growth Substances / Q000494:pharmacology; D006801:Humans; D008565:Membrane Proteins / Q000502:physiology*; D051379:Mice; D008858:Microscopy, Phase-Contrast; D011108:Polymers / Q000494:pharmacology; D011134:Polysaccharides / Q000494:pharmacology; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; D015815:Cell Adhesion Molecules; D006133:Growth Substances; D008565:Membrane Proteins; D011108:Polymers; D011134:Polysaccharides