title: [The role of intraoperative radiotherapy in oncological pediatric surgery].
abstract: Conventional external beam radiation has proved its profit in pediatric tumors; but its complications have limited it in therapeutical approach. Intraoperative radiotherapy delivers a high single dose in residual tumor or high risk areas during surgery. In our center, during last two years, 7 patients have been candidates to surgery with intraoperative radiotherapy (the age range was between 5 months-17 years; mean 8.5 years). Two patients were excluded of our protocol because of their intraoperative stage. Patients tumors types were: neuroblastoma (n = 3; stage III and IV), soft tissue sarcomas (n = 1) and Ewing's sarcoma (n = 1). The radiation doses ranged from 500 cGyto-1200 cGy. Local control tumor was achieved in 4 patients and no-complications were present secondary to surgery or intraoperative radiotherapy. Intraoperative radiotherapy seems to be a feasible treatment which might promote local control in pediatric tumors with protection of normal tissues and could be an excellent complement in special cases.
authors.affiliation: Servicio de Cirugía Pediátrica, Hospital Infantil Universitario Gregorio Marañón, Madrid.
authors.forename: G
authors.initials: G
authors.lastname: Barrientos
authors.forename: C
authors.initials: C
authors.lastname: Estellés
authors.forename: F
authors.initials: F
authors.lastname: Calvo
authors.forename: A
authors.initials: A
authors.lastname: Cantalejo
authors.forename: R
authors.initials: R
authors.lastname: Sánchez
authors.forename: R
authors.initials: R
authors.lastname: Romero
authors.forename: P
authors.initials: P
authors.lastname: Galarón
authors.forename: E
authors.initials: E
authors.lastname: Cela
authors.forename: J
authors.initials: J
authors.lastname: Vázquez
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007430:Intraoperative Care / Q000379:methods; D008297:Male; D009369:Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D010315:Particle Accelerators