Sequence similarities between human bornavirus isolates and laboratory strains question human origin.
Human bornavirus RW98, whose genome differs by 3-4% from previous isolates, is almost identical to a rat-adapted laboratory strain. Other human bornaviruses are also strongly related to virus strains frequently used for experiments in the various laboratories reporting human bornavirus, questioning a human origin of isolates known to date.
Schwemmle
M
M
Jehle
C
C
Formella
S
S
Staeheli
P
P
D000818:Animals; D001890:Borna Disease; D001891:Borna disease virus / Q000235:genetics*; D016679:Genome, Viral; D006801:Humans; D001523:Mental Disorders / Q000821:virology; D051381:Rats; D012689:Sequence Homology, Nucleic Acid; D014764:Viral Proteins / Q000235:genetics
D014764:Viral Proteins