Recurrence of hepatitis C virus infection after liver transplantation.
In patients transplanted for HCV cirrhosis, reinfection by the virus is constant. Medium-term survival is good but long-term occurrence of cirrhosis is likely to impair the long-term prognosis of these patients. Patients should be informed before transplantation of the spontaneous risk of HCV recurrence and of its consequences. As for hepatitis B in the last decade, new antiviral therapies and immunosuppressive approaches will certainly change the course of HCV after transplantation.
Samuel
D
D
Centre Hépato-Biliaire, Université Paris Sud, Contrat de Recherche INSERM 98-04, Hôpital Paul Brousse, Villejuif, France.
Feray
C
C
D005838:Genotype; D016174:Hepacivirus / Q000145:classification / Q000235:genetics / Q000502:physiology; D006526:Hepatitis C / Q000401:mortality / Q000601:surgery*; D006801:Humans; D007165:Immunosuppression Therapy; D008103:Liver Cirrhosis / Q000401:mortality / Q000601:surgery* / Q000821:virology*; D016031:Liver Transplantation; D012008:Recurrence; D015996:Survival Rate; D014779:Virus Replication