title: Delayed infections following full-face CO2 laser resurfacing and occlusive dressing use.
abstract: BACKGROUND
  Carbon dioxide (CO2) laser resurfacing has become an increasingly popular procedure for the treatment of facial rhytides and solar damage. Yet despite ongoing advancements in laser technology, CO2 laser resurfacing is still a risk-laden procedure that may lead to complications such as infection. Occlusive dressings increase the healing rate and decrease pain intensity in patients who receive full face laser resurfacing. It has been said that the use of occlusive dressings in postresurfacing patients may increase the risk of infection, which typically presents 2-10 days after the procedure.
  
  
  OBJECTIVE
  The purpose of this article is to report the incidence of infection following full-face CO2 laser resurfacing of 354 patients who were treated with occlusive dressings. In addition, factors which may have contributed to the delayed onset in three of the four infections are discussed.
  
  
  METHODS
  Three hundred fifty-four patients received full-face CO2 laser resurfacing. Either a continuous wave CO2 laser with a computer-generated scanner (396 microseconds dwell time, 18 W) or a pulsed CO2 laser (500 mJ pulse energy, 90 microseconds pulse duration) were used in all cases of resurfacing. Postoperatively all patients were treated with occlusive dressings and empiric oral cephalexin. Postoperatively patients were monitored at weekly intervals during the first month and then at 3 and 6 months.
  
  
  RESULTS
  Of the 354 patients who received full-face laser resurfacing, there were 4 cases of culture-proven infection, which translates to an infection rate of 1.13%. Three of the four infections developed 3-5 weeks after the procedure.
  
  
  CONCLUSIONS
  This study reports an infection rate of 1.13% following full-face CO2 laser resurfacing and occlusive dressing use in 354 patients. Because infection may develop many weeks after the procedure, patients should be educated to maintain proper wound care hygiene and to avoid "double dipping" of wound care products until wounds are completely healed.
authors.affiliation: University of California, Los Angeles, 90024-6933, USA.
authors.forename: M M
authors.initials: MM
authors.lastname: Christian
authors.forename: D S
authors.initials: DS
authors.lastname: Behroozan
authors.forename: R L
authors.initials: RL
authors.lastname: Moy
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects*; D009779:Occlusive Dressings / Q000009:adverse effects*; D015361:Rhytidoplasty / Q000009:adverse effects*; D017192:Skin Diseases, Bacterial / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D013530:Surgical Wound Infection / Q000382:microbiology / Q000473:pathology