Monitoring for environmental mutagenesis in wild animals--lessons from human studies.
The increasing realisation that environmental monitoring practices need to demonstrate radiological protection of the whole ecosystem has led to suggestions that genotoxic techniques derived from human monitoring of radiation exposure could be applied to other animal species. Human studies have highlighted the need to establish the relationship between exposure, genetic effect and biological consequence so that different study objectives, e.g. hazard identification, dose estimation, risk evaluation, can be addressed by the application of the most appropriate and informative assay.
Tawn
E J
EJ
Westlakes Research Institute, International Research & Graduate Centre, Westlakes Science & Technology Park, Cumbria, UK. ejt@westlakes.ac.uk
D000818:Animals; D000835:Animals, Wild / Q000235:genetics*; D002875:Chromosomes / Q000528:radiation effects; D017753:Ecosystem; D004781:Environmental Exposure; D004784:Environmental Monitoring; D005821:Genetic Techniques; D006801:Humans; D016296:Mutagenesis; D011829:Radiation Dosage; D011830:Radiation Effects; D011835:Radiation Protection; D011850:Radioactive Waste / Q000009:adverse effects; D018570:Risk Assessment
D011850:Radioactive Waste