Cytotoxicity of urushiols isolated from sap of Korean lacquer tree (Rhus vernicifera Stokes).
Cytotoxicities of four urushiols, congeners isolated from the sap of Korean lacquer tree (Rhus vernicifera Stokes), to 29 human cancer cell lines originated from 9 organs were evaluated. Their values of 50% growth inhibition were below 4 microg/ml, and showed cell line specific cytotoxicity. The present result is the first report on the cytotoxicity of urushiols suggesting that they would have an anticancer activity to human cancer cells.
Hong
D H
DH
Korea Research Institute of Bioscience and Biotechnology, Yusong, Taejon.
Han
S B
SB
Lee
C W
CW
Park
S H
SH
Jeon
Y J
YJ
Kim
M J
MJ
Kwak
S S
SS
Kim
H M
HM
D000970:Antineoplastic Agents / Q000494:pharmacology*; D002396:Catechols / Q000494:pharmacology*; D006801:Humans; D007723:Korea; D010936:Plant Extracts; D010947:Plants, Toxic; D012251:Toxicodendron / Q000737:chemistry*; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D002396:Catechols; D010936:Plant Extracts; C003747:urushiol