title: A model for intradendritic computation of binocular disparity.
abstract: Many complex cells in mammalian primary visual cortex are finely tuned to binocular disparity. In the prevailing model, several binocular simple cells drive each disparity-tuned complex cell. However, some cat complex cells receive direct LGN input, and binocular simple cells are rare in macaque. In our biophysically detailed compartmental model, active dendrites of a single neuron perform the multiple simple-cell-like subunit computations that underlie both orientation and disparity tuning. The responses of our detailed model could be predicted by a simple algebraic formula closely related to an 'energy' model. Adding inhibitory synapses led to sharper, more contrast-invariant tuning curves. Thus active dendrites could contribute to binocular-disparity tuning in complex cells.
authors.affiliation: Neuroscience Program, University of Southern California, Los Angeles, California 90089-2520, USA. karchie@Inc.usc.edu
authors.forename: K A
authors.initials: KA
authors.lastname: Archie
authors.forename: B W
authors.initials: BW
authors.lastname: Mel
mesh_terms: D000818:Animals; D002415:Cats; D003198:Computer Simulation; D003712:Dendrites / Q000502:physiology*; D000882:Haplorhini; D008959:Models, Neurological; D016571:Neural Networks, Computer; D017711:Nonlinear Dynamics; D009949:Orientation / Q000502:physiology; D017966:Pyramidal Cells / Q000502:physiology; D013569:Synapses / Q000378:metabolism; D015357:Vision Disparity / Q000502:physiology*; D014793:Visual Cortex / Q000502:physiology*