Proteolysis, cell adhesion, chemotaxis, and invasiveness are regulated by the u-PA-u-PAR-PAI-1 system.
Blasi
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Dipartimento di Ricerca Biologica e Tecnologica (DIBIT), Università Vita-Salute San Raffaele, Milano, Italy. blasi.francesco@hsr.it
D000818:Animals; D002448:Cell Adhesion / Q000502:physiology*; D002633:Chemotaxis / Q000502:physiology*; D006801:Humans; D007249:Inflammation; D009361:Neoplasm Invasiveness; D017395:Plasminogen Activator Inhibitor 1 / Q000502:physiology*; D011956:Receptors, Cell Surface / Q000502:physiology*; D055293:Receptors, Urokinase Plasminogen Activator; D015398:Signal Transduction; D014568:Urokinase-Type Plasminogen Activator / Q000502:physiology*
C524898:PLAUR protein, human; D017395:Plasminogen Activator Inhibitor 1; D011956:Receptors, Cell Surface; D055293:Receptors, Urokinase Plasminogen Activator; D014568:Urokinase-Type Plasminogen Activator