title: Anaesthesia and juvenile Huntington's disease.
abstract: Juvenile Huntington's Disease (JHD) is an involuntary movement disorder that comprises both neurological and psychiatric symptoms. Whilst it has many similarities to Huntington's Disease, it is regarded as a separate clinical entity. The anaesthetic plan should be based on careful assessment of the important issues, including the risk of regurgitation and pulmonary aspiration, possible associated autonomic neuropathy, poor respiratory function and the avoidance of precipitating convulsions and clonic spasms. We describe the management of a 12-year-old girl with JHD scheduled for gastroscopy under general anaesthesia necessitating the use of suxamethonium. We suggest an alternative mechanism for the delayed recovery seen in our patient and in other adult case reports.
authors.affiliation: Department of Anaesthetics, Northampton General Hospital NHS Trust, Cliftonville, Northampton, NN1 5BD, UK.
authors.forename: K
authors.initials: K
authors.lastname: Gupta
authors.forename: C P
authors.initials: CP
authors.lastname: Leng
mesh_terms: D000768:Anesthesia, General; D002648:Child; D005260:Female; D005773:Gastroscopy; D006801:Humans; D006816:Huntington Disease; D009467:Neuromuscular Depolarizing Agents; D013390:Succinylcholine
chemical_list: D009467:Neuromuscular Depolarizing Agents; D013390:Succinylcholine