title: Cavernous sinus syndrome associated with nonsecretory myeloma.
abstract: The case of a 53-year-old man who developed cavernous sinus syndrome (CSS) four years after being diagnosed as having nonsecretory myeloma is described. He was admitted with diplopia and dull pain over the right infraorbital and zygomatic region in June 1997. The cause of CSS was the intracranial involvement of myeloma, which was diagnosed by fiberscopic biopsy. The results of endocrinologic evaluation were almost normal. The response to radiotherapy and chemotherapy was mild. CSS caused by nonsecretory myeloma is rare and its prognosis is poor. More aggressive chemotherapy with stem cell support may be indicated.
authors.affiliation: First of Internal Medicine, Koseiren Takaoka Hospital, Takoaka, Toyama.
authors.forename: K
authors.initials: K
authors.lastname: Kyoda
authors.forename: S
authors.initials: S
authors.lastname: Nakamura
authors.forename: M
authors.initials: M
authors.lastname: Takeshima
authors.forename: S
authors.initials: S
authors.lastname: Matano
authors.forename: S
authors.initials: S
authors.lastname: Masuda
authors.forename: T
authors.initials: T
authors.lastname: Matsuda
authors.forename: H
authors.initials: H
authors.lastname: Miyakoshi
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications*; D015840:Oculomotor Nerve Diseases / Q000209:etiology*; D010255:Paranasal Sinus Neoplasms / Q000150:complications*; D013101:Sphenoid Sinus; D013577:Syndrome; D020433:Trigeminal Nerve Diseases / Q000209:etiology*