title: A P element-homologous sequence in the house fly, Musca domestica.
abstract: Sequences homologous to the P transposable element have been identified in Musca domestica. Sequence analysis of a genomic clone (Md-P1) indicates that, although the house fly P element has lost its coding capacity, the basic general structure of drosophilid P elements is present. The house fly P element sequence shares a number of structural features with that from the blow fly, Lucilia cuprina, including a large intron separating exons 1 and 2, two additional introns interrupting exon 2 and the apparent absence of inverted repeat termini. Within a relatively well-conserved central region, the house fly sequence shows 59% similarity to the D. melanogaster P element, but distal regions are more diverged. Southern blot analysis of several strains indicated the presence of at least four P element copies.
authors.affiliation: Department of Ecology and Evolutionary Biology, University of Arizona, Tucson 85721, USA.
authors.forename: S H
authors.initials: SH
authors.lastname: Lee
authors.forename: J B
authors.initials: JB
authors.lastname: Clark
authors.forename: M G
authors.initials: MG
authors.lastname: Kidwell
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004251:DNA Transposable Elements; D004175:Diptera / Q000145:classification / Q000235:genetics; D004330:Drosophila / Q000145:classification / Q000235:genetics; D015698:Genomic Library; D006793:Houseflies / Q000145:classification / Q000235:genetics*; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
chemical_list: D004251:DNA Transposable Elements