title: Browlift with botulinum toxin.
abstract: BACKGROUND
  Botulinum toxin has been used successfully for the treatment of hyperfunctional facial lines.
  
  
  OBJECTIVE
  To determine the alteration in brow position after botulinum toxin treatment of the brow depressor muscles.
  
  
  METHODS
  Eleven women, 30-60 years old, were treated. Prior to treatment, brow position was measured relative to the pupil. Relaxed position and elevated position with frontalis contraction were evaluated. Botulinum toxin was injected into bilateral eyebrows. Each brow received one injection into the glabellar region (5 U) and four equally spaced injections along the lateral orbital rim below the brow (total of 10 U). Brow position was measured for postinjection relaxed and elevated positions at three points, from the central pupil to the nasal, central, and temporal brow.
  
  
  RESULTS
  A statistically significant elevation of the right and left brows was observed in both relaxed and elevated positions. The largest mean elevations were noted in the right central brow position (relaxed 1.86 mm, elevated 2.09 mm) and the left central brow position (relaxed 3.06 mm, elevated 2.86 mm).
  
  
  CONCLUSIONS
  Botulinum toxin is a safe and effective treatment for temporary browlift. The elevations produced in the nasal, central, and temporal brow can produce an aesthetically pleasing female brow with desirable shape and height.
authors.affiliation: Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
authors.forename: W
authors.initials: W
authors.lastname: Huang
authors.forename: A S
authors.initials: AS
authors.lastname: Rogachefsky
authors.forename: J A
authors.initials: JA
authors.lastname: Foster
mesh_terms: D000328:Adult; D001905:Botulinum Toxins / Q000008:administration & dosage*; D003357:Cosmetic Techniques; D005138:Eyebrows; D005260:Female; D005546:Forehead; D006801:Humans; D007267:Injections; D008875:Middle Aged; D015595:Skin Aging
chemical_list: D001905:Botulinum Toxins