Linkage disequilibrium and recombination in hominid mitochondrial DNA.
The assumption that human mitochondrial DNA is inherited from one parent only and therefore does not recombine is questionable. Linkage disequilibrium in human and chimpanzee mitochondrial DNA declines as a function of the distance between sites. This pattern can be attributed to one mechanism only: recombination.
Awadalla
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P
Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 1JT, UK.
Eyre-Walker
A
A
Smith
J M
JM
D000818:Animals; D004272:DNA, Mitochondrial / Q000235:genetics*; D019143:Evolution, Molecular; D005220:Fathers; D005260:Female; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D015810:Linkage Disequilibrium; D008297:Male; D009245:NADH Dehydrogenase / Q000235:genetics; D002679:Pan troglodytes / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D011995:Recombination, Genetic
D004272:DNA, Mitochondrial; D009245:NADH Dehydrogenase