Intranuclear inclusions and the ubiquitin-proteasome pathway: digestion of a red herring?
Floyd
J A
JA
Biomedical Sciences Graduate Program, University of California, San Diego, La Jolla 92093, USA.
Hamilton
B A
BA
D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D000067696:Ataxin-1; D000067528:Ataxins; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D006801:Humans; D002479:Inclusion Bodies / Q000502:physiology*; D008025:Ligases / Q000235:genetics; D051379:Mice; D009097:Multienzyme Complexes / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000235:genetics; D009474:Neurons / Q000378:metabolism / Q000648:ultrastructure*; D009687:Nuclear Proteins / Q000235:genetics; D010455:Peptides / Q000378:metabolism; D046988:Proteasome Endopeptidase Complex; D017510:Protein Folding; D044767:Ubiquitin-Protein Ligases; D014452:Ubiquitins / Q000378:metabolism*
C000593749:ATXN1 protein, human; D000067696:Ataxin-1; D000067528:Ataxins; C000593750:Atxn1 protein, mouse; D009097:Multienzyme Complexes; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; D010455:Peptides; D014452:Ubiquitins; C097188:polyglutamine; D044767:Ubiquitin-Protein Ligases; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex; D000251:Adenosine Triphosphatases; D008025:Ligases