title: Spatio-temporal tracking of myocardial deformations with a 4-D B-spline model from tagged MRI.
abstract: Accurate delineation of the volumetric motion of the left ventricle (LV) of the heart from tagged magnetic resonance imaging (MRI) is an important area of research. We have built a system that takes extracted tag line features from short axis (SA) and long axis (LA) image sequences as input and fits a four-dimensional (4-D) time-varying B-spline model to the data by simultaneously fitting the model knot solids to MRI frames via matching three sequences of solid knot planes to the LV tag planes for 4-D tracking. Important advantages of the model are that reconstruction of tag surfaces, three-dimensional (3-D) material point localization, as well as displacement reconstruction are all achieved in a single step. The generated 3-D displacement fields are validated with a cardiac motion simulator, and 3-D motion fields capturing in vivo deformations in a porcine model with posterolateral myocardial infarction are illustrated.
authors.affiliation: Cardiovascular Image Analysis Laboratory, Washington University in St. Louis, MO 63110, USA. huang.amini@cauchy.wustl.edu
authors.forename: J
authors.initials: J
authors.lastname: Huang
authors.forename: D
authors.initials: D
authors.lastname: Abendschein
authors.forename: V G
authors.initials: VG
authors.lastname: Dávila-Román
authors.forename: A A
authors.initials: AA
authors.lastname: Amini
mesh_terms: D000818:Animals; D006352:Heart Ventricles / Q000473:pathology; D016018:Least-Squares Analysis; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000706:statistics & numerical data; D008955:Models, Cardiovascular; D009038:Motion; D009206:Myocardium / Q000473:pathology*; D013552:Swine; D013997:Time Factors