[Eye and sarcoidosis].
Sarcoidosis is a multisystem granulomatous disease, of unknown cause, characterised by non-caseating granulomas. The most common organs involved are the lung, thoracic lymph nodes, skin and eyes. Ophthalmic involvement occurred in approximately 30% of the patients and could be the first manifestation of the disease and preceding pulmonary involvement for many years. If anterior uveitis is the most common ocular manifestation, the posterior segment involvement (intermediate uveitis, vasculitis, choroidal granuloma, macular oedema...) is less common but more visually disabling. The non specific ocular manifestations of the disease make it as a difficult diagnosis. The "suspected sarcoidosis" diagnosis is made with regards to clinical, radiological and (or) biological criteria and the "definitive diagnosis" require the demonstration of a non-caseating, granulomatous, non-infectious inflammation process on biopsy.
Weber
M
M
Clinique ophtalmologique CHU de Nantes, hôtel-Dieu, Nantes.
D015862:Choroid Diseases / Q000175:diagnosis; D003229:Conjunctival Diseases / Q000175:diagnosis; D003937:Diagnosis, Differential; D005128:Eye Diseases / Q000175:diagnosis*; D005451:Fluorescein Angiography; D006099:Granuloma / Q000175:diagnosis; D006801:Humans; D011379:Prognosis; D012507:Sarcoidosis / Q000175:diagnosis* / Q000188:drug therapy; D014606:Uveitis, Anterior / Q000175:diagnosis; D015866:Uveitis, Posterior / Q000175:diagnosis