title: Cloning of the Arabidopsis RTM1 gene, which controls restriction of long-distance movement of tobacco etch virus.
abstract: The locus RTM1 is necessary for restriction of long-distance movement of tobacco etch virus in Arabidopsis thaliana without causing a hypersensitive response or inducing systemic acquired resistance. The RTM1 gene was isolated by map-based cloning. The deduced gene product is similar to the alpha-chain of the Artocarpus integrifolia lectin, jacalin, and to several proteins that contain multiple repeats of a jacalin-like sequence. These proteins comprise a family with members containing modular organizations of one or more jacalin repeat units and are implicated in defense against viruses, fungi, and insects.
authors.affiliation: Institute of Biological Chemistry, Washington State University, Pullman, WA 99164-6340, USA.
authors.forename: S T
authors.initials: ST
authors.lastname: Chisholm
authors.forename: S K
authors.initials: SK
authors.lastname: Mahajan
authors.forename: S A
authors.initials: SA
authors.lastname: Whitham
authors.forename: M L
authors.initials: ML
authors.lastname: Yamamoto
authors.forename: J C
authors.initials: JC
authors.lastname: Carrington
mesh_terms: D000595:Amino Acid Sequence; D000998:Antiviral Agents / Q000737:chemistry; D017360:Arabidopsis / Q000235:genetics*; D029681:Arabidopsis Proteins; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D017343:Genes, Plant; D037102:Lectins / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D037121:Plant Lectins; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics*; D010942:Plant Viruses / Q000472:pathogenicity; D016415:Sequence Alignment
chemical_list: D000998:Antiviral Agents; D029681:Arabidopsis Proteins; D037102:Lectins; D037121:Plant Lectins; D010940:Plant Proteins; C403528:RTM1 protein, Arabidopsis; C043696:jacalin