[Morphological aspects of the normal and pathological liver].
Although the liver is a complex organ connected to vascular and duct network, it reacts to insults in a fairly unvarying manner. Correlations between tissue damage severity and abnormalities in clinical and laboratory test findings are usually poor, and as a result, liver biopsy remains a key investigation for the diagnosis and follow-up of chronic liver diseases. Systematic analysis of the type, severity and distribution of lesions of the parenchyma, portal triads and centrolobular veins usually allows to suggest a cause and to evaluate the prognosis. This requires comparison to normal liver histology. The normal histological features and main elemental lesions seen in the human liver are discussed in this article.
Bedossa
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Service d'Anatomie Pathologique, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
D001706:Biopsy; D002908:Chronic Disease; D006801:Humans; D008099:Liver / Q000098:blood supply / Q000473:pathology*; D008107:Liver Diseases / Q000175:diagnosis / Q000473:pathology*