title: Allele frequency distributions of six Amp-FLPS (D1S80, APO-B, VWA, TH01, CSF1PO and HPRTB) in a Mexican population.
abstract: Six amplified fragment length polymorphisms or Amp-FLPs, two VNTRs (D1S80 and APO-B) and four STRs (VWA, TH01, CSF1PO and HPRTB), were typed in a Mexican population of the Jalisco state by means of non-denaturing polyacrylamide gel electrophoresis (native PAGE) in standard gel units and silver staining. Genotype distribution was in agreement with Hardy-Weinberg expectations (HWE) for all six markers. Heterozygosity ranged from 70.6 to 83.5%, the cumulated chance of exclusion (CE) and power of discrimination (PD) were 99.4 and 99.99%, respectively. STRs and D1S80 allele frequency distributions (AFD) were similar (P > 0.05) to U.S. Hispanics, but different to U.S. Caucasians and African-Americans. APO-B exhibited similarities with White Brazilians, Spaniards, but differences (P < 0.05) with Amerindian and Black Brazilians.
authors.affiliation: División de Genética, Centro de Investigación Biomédica de Occidente (CIBO-IMSS), Guadalajara, Jalisco, Mexico. lef@koch.mb.udg.mx
authors.forename: H
authors.initials: H
authors.lastname: Rangel-Villalobos
authors.forename: F
authors.initials: F
authors.lastname: Rivas
authors.forename: M
authors.initials: M
authors.lastname: Torres-Rodríguez
authors.forename: A R
authors.initials: AR
authors.lastname: Jaloma-Cruz
authors.forename: M P
authors.initials: MP
authors.lastname: Gallegos-Arreola
authors.forename: J
authors.initials: J
authors.lastname: López-Satow
authors.forename: J M
authors.initials: JM
authors.lastname: Cantú
authors.forename: L E
authors.initials: LE
authors.lastname: Figuera
mesh_terms: D000483:Alleles; D044383:Black People / Q000235:genetics; D001938:Brazil; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D005787:Gene Frequency; D006630:Hispanic or Latino / Q000235:genetics; D006801:Humans; D007198:Indians, North American / Q000235:genetics; D008297:Male; D008800:Mexico; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D044465:White People / Q000235:genetics*; D001741:Black or African American