title: [Role of 99mTC-Sestamibi in the diagnosis of breast cancer. Report on 100 cases].
abstract: OBJECTIVE
  To evaluate the usefulness of the isotopic mammography with 99mTc-MIBI in the diagnosis of tumoral pathology of the mammary gland.
  
  
  METHODS
  One hundred women with clinical/radiological suspicion of malignant pathology in the breast and/or lymph nodes were studied. The isotopic technique consisted of administration 740MBq 99mTc-MIBI, i.v., obtaining AP and prone lateral views.
  
  
  RESULTS
  The overall sensitivity and specificity for the scintimammography in tumoral detection was 90% and 86% respectively. The sensitivity was 60% in nonpalpable lesions. The scintimammography had a 40% sensitivity and 98% specificity in lymph node detection.
  
  
  CONCLUSIONS
  The complementary use of scintimammography can improve the sensitivity for the detection of breast carcinoma. The diagnostic accuracy of 99mTc-MIBI depends on the tumor size and histopathological characteristics. The 99mTc-MIBI can potentially determine the presence of recurrent breast cancer and multicentric disease.
authors.affiliation: Servicio de Medicina Nuclear, Fundación Intituto Valenciano de Oncología (IVO), Valencia, 46009, España.
authors.forename: M V
authors.initials: MV
authors.lastname: Fliquete Peris
authors.forename: J
authors.initials: J
authors.lastname: Giménez Climent
authors.forename: C
authors.initials: C
authors.lastname: Vázquez Forner
authors.forename: C
authors.initials: C
authors.lastname: Más Arcas
authors.forename: C
authors.initials: C
authors.lastname: Vázquez Albaladejo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi