title: Spontaneous spondylodiscitis caused by Klebsiella pneumoniae.
abstract: A rare case of spontaneous spondylodiscitis caused by Klebsiella pneumoniae in a 55-year-old man who presented with thoracolumbar pain is described. Increased erythrocyte sedimentation rate and C-reactive protein level were pertinent laboratory findings. Computed tomography revealed a paravertebral mass and destruction of the 10th and 11th vertebrae. Magnetic resonance imaging (MRI) showed spondylodiscitis in the same area. Culture of a biopsy sample from the mass grew Klebsiella pneumoniae, while histological examination confirmed the inflammation. A combination of ceftazidime, amikacin and ciprofloxacin resulted in disappearance of the pain. Two months later, MRI showed substantial improvement of the lesions.
authors.affiliation: University of Crete, Division of Medicine, Greece.
authors.forename: C
authors.initials: C
authors.lastname: Kouroussis
authors.forename: V
authors.initials: V
authors.lastname: Georgoulias
authors.forename: J
authors.initials: J
authors.lastname: Souglakos
authors.forename: E
authors.initials: E
authors.lastname: Simvoulakis
authors.forename: S
authors.initials: S
authors.lastname: Karabekios
authors.forename: G
authors.initials: G
authors.lastname: Samonis
mesh_terms: D000583:Amikacin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001706:Biopsy; D002442:Ceftazidime / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D015299:Discitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007710:Klebsiella Infections / Q000175:diagnosis* / Q000188:drug therapy; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000302:isolation & purification; D008297:Male; D008875:Middle Aged
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D002511:Cephalosporins; D002939:Ciprofloxacin; D000583:Amikacin; D002442:Ceftazidime