title: Calcium treatment for premenstrual syndrome.
abstract: OBJECTIVE
  To evaluate the use of calcium supplementation in the treatment of premenstrual syndrome.
  
  
  METHODS
  Clinical literature accessed through MEDLINE (from January 1967 to September 1999). Key search terms included calcium, PMS, and premenstrual.
  
  
  RESULTS
  Up to 50% of women experience some form of premenstrual syndrome. An evaluation of studies focusing on calcium in the management of premenstrual symptoms was conducted.
  
  
  CONCLUSIONS
  Calcium supplementation of 1200-1600 mg/d, unless contraindicated, should be considered a sound treatment option in women who experience premenstrual syndrome. The supplemental dose of calcium can be adjusted downward in the few patients who routinely consume large quantities of calcium in their diet.
authors.affiliation: College of Pharmacy, University of Tennessee, Memphis 38163, USA.
authors.forename: M W
authors.initials: MW
authors.lastname: Ward
authors.forename: T D
authors.initials: TD
authors.lastname: Holimon
mesh_terms: D000328:Adult; D002118:Calcium / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D011293:Premenstrual Syndrome / Q000188:drug therapy*
chemical_list: D002118:Calcium