title: The use of composite acellular allodermis-ultrathin autograft on joint area in major burn patients--one year follow-up.
abstract: Scar contracture is a major long-term sequelae of meshed split-thickness skin grafts in the case of full-thickness burn injuries, and especially in joint areas. Severe contracture around joints may lead to loss of mobility. The thickness of the dermis in the autograft plays a major role in the functional and cosmetic outcomes of the third degree burn. How to replace lost dermis is a major problem in skin restoration following severe burns. The human allograft skin (AlloDerm) is an acellular dermal matrix with normal collagen bundling organization and intact basement membrane complex. We present 12 cases of clinical application of a composite grafting technique in which the allogeneic skin (AlloDerm) provided source of dermis, and an ultrathin autograft (0.004-0.006 inch in thickness) provided epidermis. In these patients, The composite grafts were applied to full-thickness burn wounds over various articular skin surfaces. The average skin graft take rate was 91.5%. These ultrathin autografts allow the donor sites to heal faster. The mean time of donor site reepithelization was 6 days. All patients had a nearly normal range of joint motion (average 95% of normal) after one year's follow up. Wound assessment over time has shown supple skin that has been resistant to trauma and infection. The cosmetic results were judged to be fair to good by surgeons and patients after one year's follow up.
authors.affiliation: Department of Surgery, Chung-Ho Memorial Hospital, Kaohsiung Medical University, Taiwan, Republic of China.
authors.forename: C C
authors.initials: CC
authors.lastname: Tsai
authors.forename: S D
authors.initials: SD
authors.lastname: Lin
authors.forename: C S
authors.initials: CS
authors.lastname: Lai
authors.forename: T M
authors.initials: TM
authors.lastname: Lin
mesh_terms: D000328:Adult; D002056:Burns / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016038:Skin Transplantation; D014182:Transplantation, Autologous