Seroconversion of hepatitis B during chemotherapy for malignant lymphoma.
We report a patient with chronic hepatitis B infection who developed lymphoma and was treated with concomitant cytotoxic and antiviral therapy. In contrast to the expected life threatening fulminant hepatitis that is often reported in this clinical setting, in our patient normalization of liver function tests with temporary loss of viral replication markers were seen. The implications of this rare clinical and serological course are discussed.
Kitay-Cohen
Y
Y
Department of Medicine, Meir General Hospital, Kfar Saba and Sackler Faculty of Medicine, Tel-Aviv University, Israel.
Elis
A
A
Lalkin
A
A
Lishner
M
M
D000328:Adult; D004279:DNA, Viral / Q000097:blood; D006513:Hepatitis B e Antigens / Q000097:blood; D019694:Hepatitis B, Chronic / Q000188:drug therapy*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy* / Q000821:virology; D008297:Male; D014779:Virus Replication
D004279:DNA, Viral; D006513:Hepatitis B e Antigens