title: Fatal Hemoptysis during Coronary Thrombolysis.
abstract: Cerebral hemorrhage is the most dreaded complication of coronary thrombolysis. Significant bleeding has also been described from catheter-entry sites, the retroperitoneum, and the gastrointestinal and genitourinary tracts. However, hemoptysis induced by thrombolysis has rarely been described in the literature. We present a 66-year-old male who received front-loaded tissue plasminogen activator (tPA) for acute transmural anterior wall myocardial infarction and developed massive hemoptysis from preexisting cavitary lung disease. The patient died within 5 hours. We believe this is the first case report of fatal hemoptysis induced by coronary thrombolysis. A history of cavitary lung disease may be a risk factor for life-threatening hemoptysis in patients receiving thrombolytic therapy.
authors.affiliation: Division of Cardiology and Pulmonary Medicine, Bronx-Lebanon Hospital Center, Bronx, New York; Department of Medicine, Bronx-Lebanon Hospital Center, Bronx, New York and Department of Pathology, Bronx-Lebanon Hospital Center, Bronx, New York.
authors.initials: AW
authors.lastname: Basher
authors.initials: A
authors.lastname: Oduwole
authors.initials: NC
authors.lastname: Bhalodkar
authors.initials: B
authors.lastname: Mohideen
authors.initials: E
authors.lastname: Sy
authors.initials: A
authors.lastname: Sehonanda
authors.lastname: Brown Jr