title: Neuroblastoma and parental occupation.
abstract: OBJECTIVE
  We evaluated parental occupation and the risk of neuroblastoma using data from a large case-control study conducted by the Children's Cancer Group and the Pediatric Oncology Group.
  
  
  METHODS
  We compared the distribution of 73 paternal and 57 maternal occupational groups among 504 newly diagnosed cases of neuroblastoma and individually matched controls obtained by telephone random digit dialing in the United States and Canada.
  
  
  RESULTS
  An increased risk of neuroblastoma was found for fathers employed as broadcast, telephone and dispatch operators (odds ratio [OR] = 6.1; 95% confidence interval [CI] = 0.7-50.9), electrical power installers and power plant operators (OR = 2.7; CI = 0.9-8.1), landscapers and groundskeepers (OR = 2.3; CI = 1.0-5.2), and painters (OR = 2.1; CI = 0.9-4.8). Elevated odds ratios were found for mothers employed as farmers and farm workers (OR = 2.2; CI = 0.6-8.8), florists and garden store workers (OR = 2.4; CI = 0.6-9.9), hairdressers and barbers (OR = 2.8; CI = 1.2-6.3), electric power installers and power plant operators, and sailors, fishers, and railroad workers. No increase in risk was found for other paternal occupations previously associated, including electricians, electrical equipment assemblers and repairers (OR = 1.1; CI = 0.6-2.0), or welders (OR = 0.5; CI = 0.1-1.6).
  
  
  CONCLUSIONS
  The study reinforced some prior evidence of increased risks in electrical, farming and gardening, and painting occupations, but failed to confirm other previously reported associations. Further analyses of exposure to electromagnetic fields, metals, solvents, and pesticides are currently under way.
authors.affiliation: Department of Epidemiology, School of Public Health University of North Carolina, Chapel Hill, USA. andy_olshan@unc.edu
authors.forename: A F
authors.initials: AF
authors.lastname: Olshan
authors.forename: A J
authors.initials: AJ
authors.lastname: De Roos
authors.forename: K
authors.initials: K
authors.lastname: Teschke
authors.forename: J P
authors.initials: JP
authors.lastname: Neglia
authors.forename: D O
authors.initials: DO
authors.lastname: Stram
authors.forename: B H
authors.initials: BH
authors.lastname: Pollock
authors.forename: R P
authors.initials: RP
authors.lastname: Castleberry
mesh_terms: D000293:Adolescent; D000328:Adult; D002170:Canada / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D016015:Logistic Models; D008297:Male; D009447:Neuroblastoma / Q000453:epidemiology* / Q000209:etiology; D016273:Occupational Exposure / Q000009:adverse effects; D009790:Occupations / Q000706:statistics & numerical data*; D016017:Odds Ratio; D010290:Parents; D012307:Risk Factors; D014481:United States / Q000453:epidemiology