Antiviral activity of some Nigerian medicinal plant extracts.
Plants from Northern Nigeria with a history of use in both human and veterinary traditional medicine have been investigated for their antiviral activity and their cytotoxicity determined. Extracts were tested against poliovirus, astrovirus, herpes simplex viruses and parvovirus, using the microtitre plate inhibition tests. Most of the extracts have activity against more than one virus at a dose rate of between 100 and 400 microg/100 microl.
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Department of Microbiology and Immunology, University of Leicester, Medical Sciences Building, UK. ack5@leicester.ac.uk
Myint
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D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D018938:Caco-2 Cells / Q000502:physiology; D000882:Haplorhini; D006801:Humans; D066298:In Vitro Techniques; D007668:Kidney / Q000502:physiology; D001257:Mamastrovirus / Q000187:drug effects; D008519:Medicine, Traditional; D008832:Microchemistry; D009549:Nigeria; D017992:Parvovirus / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D017955:Poliovirus / Q000187:drug effects; D018139:Simplexvirus / Q000187:drug effects
D000998:Antiviral Agents; D010936:Plant Extracts