title: The experience in the treatment of patients with extensive full-thickness burns.
abstract: The aim of the present study is to analyze the changes of cure rate and the main causes of death in the last 40 years, and to summarize our experience in the treatment of extensive full-thickness burn patients. The clinical characteristics, cure rate and main causes of death of 73 cases with total burned area more than 90% TBSA and full-thickness burn area more than 70% TBSA were analyzed retrospectively. Among them, 21 cases (28.8%) were cured and 52 cases (71.2%) died. The cure rate increased significantly in the recent years, and the main causes of death changed from shock and sepsis in the time period 1959-1978 to sepsis and MODS in the past two decades. Due to the improvement of early comprehensive management of burn shock, aggressive surgical approach to full-thickness burn wound and potent systemic supporting measures, the survival rate increased significantly.
authors.affiliation: Burns Center, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China. httang@smmu.edu.cn
authors.forename: H
authors.initials: H
authors.lastname: Tang
authors.forename: X
authors.initials: X
authors.lastname: Zhaofan
authors.forename: S
authors.initials: S
authors.lastname: Liu
authors.forename: Y
authors.initials: Y
authors.lastname: Chen
authors.forename: S
authors.initials: S
authors.lastname: Ge
mesh_terms: D000328:Adult; D002053:Burn Units / Q000706:statistics & numerical data; D002056:Burns / Q000150:complications / Q000401:mortality / Q000628:therapy*; D002423:Cause of Death; D006801:Humans; D015994:Incidence; D009102:Multiple Organ Failure / Q000453:epidemiology / Q000209:etiology; D011379:Prognosis; D012151:Resuscitation / Q000401:mortality; D012189:Retrospective Studies; D018805:Sepsis / Q000453:epidemiology / Q000209:etiology; D015996:Survival Rate; D015599:Trauma Severity Indices