Complete response to topotecan of recurrent fallopian tube carcinoma.
OBJECTIVE
To describe the first complete response of recurrent Fallopian tube carcinoma to topotecan.


METHODS
A patient with recurrent Fallopian tube carcinoma previously treated with paclitaxel (Taxol) and carboplatin is described.


RESULTS
This patient demonstrated a complete clinical response to topotecan. Radiographic and CA-125 measurements were used to determine response. Response was noted after four cycles and a complete response demonstrated after six treatments.


CONCLUSIONS
Topotecan appears active in recurrent Fallopian tube carcinoma.
Dunton
C J
CJ
Department of Obstetrics and Gynecology, Jefferson Medical College, Philadelphia, Pennsylvania, 19107, USA.
Neufeld
J
J
D000368:Aged; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D018394:CA-125 Antigen / Q000032:analysis; D005185:Fallopian Tube Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D019772:Topotecan / Q000494:pharmacology / Q000627:therapeutic use*; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D018394:CA-125 Antigen; D019772:Topotecan