Primary non Hodgkin's lymphoma of the vagina.
The genital tract as a primary site of malignant lymphoma in women is extremely rare. This report concerns a 64 year old patient with a primary vaginal non-Hodgkin lymphoma (large cell B lineage according to the REAL classification--centroblastic type according to the Kiel classification--"G" according Working Formulation) with an unusual clinical presentation--pelvic discomfort accompanied by frequent ureteral-like colic. Due to gynecological onset symptoms and the rarity of this extranodal primary site misinterpretation of a primary vaginal lymphoma as a benign inflammatory disease or endometriosis may occur. We emphasize the importance of their recognition and also the differential diagnosis of cervical lymphoma from other neoplastic and non-neoplastic lesions.
Guarini
A
A
Haematology Department, University of Bari, Italy. attguar@tin.it
Pavone
V
V
Valentino
T
T
Rana
A
A
Di Vagno
G
G
Maiorano
E
E
Liso
V
V
D015746:Abdominal Pain / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged; D000292:Pelvic Inflammatory Disease / Q000150:complications / Q000175:diagnosis; D017699:Pelvic Pain / Q000209:etiology*; D014517:Ureteral Obstruction / Q000150:complications; D014625:Vaginal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology*