Production, isolation and biological properties of TMC-120A, B and C, novel inhibitors of eosinophil survival from Aspergillus ustus TC 1118.
Kohno
J
J
Discovery Research Laboratory, Tanabe Seiyaku Co., Ltd., Japan.
Sakurai
M
M
Kameda
N
N
Nishio
M
M
Kawano
K
K
Kishi
N
N
Okuda
T
T
Komatsubara
S
S
D000470:Alkaloids / Q000302:isolation & purification* / Q000494:pharmacology*; D000818:Animals; D001230:Aspergillus; D001572:Benzofurans / Q000302:isolation & purification* / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D004804:Eosinophils / Q000187:drug effects* / Q000378:metabolism; D005285:Fermentation; D006168:Guinea Pigs; D015848:Interleukin-5 / Q000037:antagonists & inhibitors; D007546:Isoquinolines / Q000302:isolation & purification* / Q000494:pharmacology*; D015394:Molecular Structure; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D000470:Alkaloids; D001572:Benzofurans; D015848:Interleukin-5; D007546:Isoquinolines; C402696:TMC 120A; C402697:TMC 120B; C402698:TMC 120C