Homology-dependent gene silencing in plants and fungi: a number of variations on the same theme.
Homology-dependent gene silencing is a phenomenon that occurs in a broad range of organisms and has implications for both basic and applied science. Gene silencing is a mechanism that controls invading transposons and provides protection against virus infections. It also has evolutionary implications in genome maintenance. Recent studies have begun to unravel the molecular mechanisms of this puzzling phenomenon.
Cogoni
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Dipartimento di Biotecnologie Cellulari ed Ematologia, Sezione di Genetica Molecolare, Universita' di Roma La Sapienza, Roma, 00161, Italy. carlo@bce.med.uniroma1.it
Macino
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D005658:Fungi / Q000235:genetics* / Q000254:growth & development; D015966:Gene Expression Regulation, Fungal; D018506:Gene Expression Regulation, Plant; D020868:Gene Silencing; D063245:Plant Development; D010944:Plants / Q000235:genetics*; D017385:Sequence Homology; D014158:Transcription, Genetic; D019076:Transgenes