Identification of four loci isolated from two Streptococcus thermophilus phage genomes responsible for mediating bacteriophage resistance.
Sequence data derived from the Streptococcus thermophilus phages phiO1205 and phi7201 indicated that each of these phages contains a distinct DNA region dedicated to replication. Southern blotting experiments showed that phages infecting S. thermophilus may be divided into at least two groups, each containing the presumptive replication functions of either &phi;O1205 (group I) or &phi;7201 (group II). Specific regions from the putative replication module of each of the two phages were examined for their ability to provide phage resistance.
Stanley
E
E
National Food Biotechnology Centre, University College Cork, Cork, Ireland.
Walsh
L
L
van der Zwet
A
A
Fitzgerald
G F
GF
van Sinderen
D
D
D001483:Base Sequence; D004279:DNA, Viral / Q000235:genetics; D008969:Molecular Sequence Data; D016366:Open Reading Frames / Q000235:genetics; D010957:Plasmids / Q000235:genetics; D018741:Replication Origin / Q000235:genetics*; D017422:Sequence Analysis, DNA; D013291:Streptococcus / Q000821:virology*; D017108:Streptococcus Phages / Q000235:genetics* / Q000502:physiology*; D014779:Virus Replication
D004279:DNA, Viral