title: Deletion (1)(q12) and double minutes in a metastatic adenocarcinoma of the prostate.
abstract: Cytogenetic analysis after short-term cultures were performed on an invasive and moderately-differentiated prostatic adenocarcinoma. The results showed a normal male chromosomal complement in most metaphases examined. Furthermore, several abnormalities were found, including del(1)(q12), double minute and ring chromosomes, acentric fragments, triradial figures, and near-tetraploid cells.
authors.affiliation: Departmento de Biologia, Instituto de Biociências, Letras e Ciências Exatas, São José do Rio Preto, Brazil.
authors.forename: A B
authors.initials: AB
authors.lastname: Carvalho-Salles
authors.forename: J C
authors.initials: JC
authors.lastname: Mesquita
authors.forename: E H
authors.initials: EH
authors.lastname: Tajara
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics*; D000368:Aged; D002878:Chromosomes, Human, Pair 1; D017353:Gene Deletion; D006801:Humans; D007621:Karyotyping; D008297:Male; D009362:Neoplasm Metastasis; D011003:Ploidies; D011471:Prostatic Neoplasms / Q000235:genetics*; D012303:Ring Chromosomes; D014407:Tumor Cells, Cultured