title: Quantification of left ventricular diastolic wall motion by Doppler tissue imaging in healthy cats and cats with cardiomyopathy.
abstract: OBJECTIVE
  To assess Doppler tissue imaging (DTI) for evaluating left ventricular diastolic wall motion in healthy cats and cats with cardiomyopathy.
  
  
  METHODS
  20 healthy cats, 9 cats with hypertrophic cardiomyopathy (HCM), and 9 cats with unclassified cardiomyopathy (UCM).
  
  
  METHODS
  A pulsed wave DTI sample gate was positioned at a subendocardial region of the left ventricular free wall in the short axis view and at the lateral mitral annulus in the apical 4-chamber view. Indices of diastolic wall motion were measured, including peak diastolic velocity (PDV), mean rate of acceleration and deceleration of the maximal diastolic waveform (MDWaccel and MDWdecel, respectively), and isovolumetric relaxation time (IVRT).
  
  
  RESULTS
  The PDV of cats with HCM and 6 of 9 cats with UCM was significantly decreased, compared with that of healthy cats. In the 3 cats with UCM that had a PDV that was not different from healthy cats, MDWaccel and MDWdecel were greater, and IVRT was shorter than those of healthy cats. The IVRT in cats with HCM was longer than that of other cats.
  
  
  CONCLUSIONS
  Indices of diastolic function in cats with HCM, and in many cats with UCM, differed from those of healthy cats and were similar to those reported in humans with HCM and restrictive cardiomyopathy, respectively. However, the hemodynamic abnormality was not the same for all cats with UCM; some cats with an enlarged left atrium and a normal left ventricle (ie, UCM) had abnormal left ventricular wall motion consistent with restrictive cardiomyopathy while others did not.
authors.affiliation: Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA.
authors.forename: B J
authors.initials: BJ
authors.lastname: Gavaghan
authors.forename: M D
authors.initials: MD
authors.lastname: Kittleson
authors.forename: K J
authors.initials: KJ
authors.lastname: Fisher
authors.forename: P H
authors.initials: PH
authors.lastname: Kass
authors.forename: M A
authors.initials: MA
authors.lastname: Gavaghan
mesh_terms: D000818:Animals; D009202:Cardiomyopathies / Q000000981:diagnostic imaging / Q000662:veterinary*; D002371:Cat Diseases / Q000000981:diagnostic imaging*; D002415:Cats; D018618:Echocardiography, Doppler, Color; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D008297:Male; D009200:Myocardial Contraction