Normal movement reading in Asperger subjects.
Patients with autism and Asperger syndrome (AS) are impaired in mindreading and imitation skills. One possibility would be that their 'mirror neuron' system, which matches action execution and observation, does not function properly. To test this hypothesis we compared action-viewing related motor cortex functions in an AS group (one autistic and four AS subjects) and eight control subjects. In both groups viewing hand actions modified the neuromagnetic approximately 20 Hz oscillatory activity in the primary motor cortex to the same extent. Thus impaired mindreading and imitation skills found in AS and autism do not seem to result from dysfunction of the motor cortex part of the action execution/observation system.
Avikainen
S
S
Brain Research Unit, Helsinki University of Technology, Finland.
Kulomäki
T
T
Hari
R
R
D000328:Adult; D020817:Asperger Syndrome / Q000503:physiopathology*; D001321:Autistic Disorder / Q000503:physiopathology; D003071:Cognition / Q000502:physiology; D004558:Electric Stimulation; D005260:Female; D006225:Hand / Q000502:physiology; D006801:Humans; D007100:Imitative Behavior / Q000502:physiology; D015225:Magnetoencephalography; D008297:Male; D008475:Median Nerve / Q000502:physiology; D008959:Models, Neurological; D009039:Motion Perception / Q000502:physiology*; D009044:Motor Cortex / Q000502:physiology*; D009068:Movement; D010775:Photic Stimulation