Mucosal immunization with DNA vaccines.
DNA vaccines can induce potent humoral and cellular immune responses in numerous animal models. Most DNA vaccines have been administered parenterally; however, more effective protection against mucosal pathogens could be achieved with mucosal immunization. This review concentrates on the use of DNA vaccines for the induction of mucosal immunity.
McCluskie
M J
MJ
Loeb Health Research Institute at the Ottawa Hospital, 725 Parkdale Avenue, Ottawa K1Y 4E9, Canada.
Davis
H L
HL
D000818:Animals; D006801:Humans; D018928:Immunity, Mucosal; D014611:Vaccination / Q000379:methods*; D019444:Vaccines, DNA / Q000008:administration & dosage / Q000276:immunology*
D019444:Vaccines, DNA