Breastfeeding in phenylketonuria.
Eighty-three infants with classical phenylketonuria have been born in Norway since 1979. The treatment of these children is centralized at the National Hospital in Oslo. Seventy-four have been breastfed in combination with a phenylalanine-free protein substitute. Dietary treatment was commenced in hospital between 5 and 33 d of age (mean 14 d). Normalization of serum phenylalanine (below 400 pmol/l) took between 1 and 35 d (mean 8 d). The period of breastfeeding lasted from 1 to 16 mo (mean 7 mo). Growth (weight, length and head circumference) fell within the normal range for age on the Norwegian growth chart.
Motzfeldt
K
K
Department of Pediatric Research, The National Hospital, Oslo, Norway. kristina.motzfelt@klinmed.uio.no
Lilje
R
R
Nylander
G
G
D001942:Breast Feeding; D002657:Child Development / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007225:Infant Food; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D008297:Male; D009664:Norway; D010649:Phenylalanine / Q000097:blood*; D010661:Phenylketonurias / Q000097:blood / Q000175:diagnosis / Q000178:diet therapy*; D016896:Treatment Outcome
D010649:Phenylalanine