[Ovarian tissue banking--primary results].
Lifelong hormone replacement therapy and infertility often follow oncological therapy in young women due to a dramatic reduction of the primordial follicle reserve. Reimplantation and function of frozen ovarian tissue slices were successfully demonstrated in animal models, but the durability is limited. Cryopreservation of a whole ovary could reestablish an almost normal ovarian function. Experiments with porcine ovaries showed histological viability. Cryopreservation and retransplantation of sheep ovaries should demonstrate success by hormonal response and pregnancy.
Imhof
M
M
Universitäts-Frauenklinik, Wien, Osterreich. martin.imhof@akh-wien.ac.at
Hofstetter
G
G
Bergmeister
H
H
Rudas
M
M
Kain
R
R
Wenzl
R
R
Huber
J C
JC
D000818:Animals; D015925:Cryopreservation; D005260:Female; D006801:Humans; D008594:Menopause, Premature / Q000502:physiology*; D008854:Microscopy, Electron; D010053:Ovary / Q000473:pathology / Q000637:transplantation*; D011247:Pregnancy; D012092:Replantation; D012756:Sheep; D013552:Swine; D014015:Tissue Banks