Excretion of B virus in monkeys and evidence of genital infection.
3 different types of observation all demonstrated that B virus (Herpesvirus simiae) infection of monkeys was not confined to the mouth but was also a genital infection. (1) Latent B virus was reactivated in a seropositive female monkey, which was immunosuppressed with antilymphocyte globulin, and infectious virus was excreted in the genital tract. (2) During an epizootic in a breeding colony, B virus was isolated from 4 genital and 3 oral sites as well as from a skin lesion. (3) In cultures of sensory nerve ganglia taken from seropositive monkeys, B virus was recovered more frequently from ganglia subserving the genital region than the oral region.
Zwartouw
H T
HT
Chemical Defence Establishment, Porton Down, Salisbury, Wiltshire, United Kingdom.
Boulter
E A
EA
D000818:Animals; D004196:Disease Outbreaks / Q000662:veterinary; D005260:Female; D005835:Genitalia / Q000821:virology; D006566:Herpesviridae Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D006568:Herpesvirus 1, Cercopithecine / Q000302:isolation & purification / Q000502:physiology*; D008252:Macaca fascicularis; D008297:Male; D008992:Monkey Diseases / Q000453:epidemiology / Q000821:virology*; D009055:Mouth / Q000821:virology; D017735:Virus Latency; D017201:Virus Shedding