title: Cytotoxicity of urushiols isolated from sap of Korean lacquer tree (Rhus vernicifera Stokes).
abstract: Cytotoxicities of four urushiols, congeners isolated from the sap of Korean lacquer tree (Rhus vernicifera Stokes), to 29 human cancer cell lines originated from 9 organs were evaluated. Their values of 50% growth inhibition were below 4 microg/ml, and showed cell line specific cytotoxicity. The present result is the first report on the cytotoxicity of urushiols suggesting that they would have an anticancer activity to human cancer cells.
authors.affiliation: Korea Research Institute of Bioscience and Biotechnology, Yusong, Taejon.
authors.forename: D H
authors.initials: DH
authors.lastname: Hong
authors.forename: S B
authors.initials: SB
authors.lastname: Han
authors.forename: C W
authors.initials: CW
authors.lastname: Lee
authors.forename: S H
authors.initials: SH
authors.lastname: Park
authors.forename: Y J
authors.initials: YJ
authors.lastname: Jeon
authors.forename: M J
authors.initials: MJ
authors.lastname: Kim
authors.forename: S S
authors.initials: SS
authors.lastname: Kwak
authors.forename: H M
authors.initials: HM
authors.lastname: Kim
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D002396:Catechols / Q000494:pharmacology*; D006801:Humans; D007723:Korea; D010936:Plant Extracts; D010947:Plants, Toxic; D012251:Toxicodendron / Q000737:chemistry*; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D002396:Catechols; D010936:Plant Extracts; C003747:urushiol