Calcium-channel blocker withdrawal in a pregnant woman.
We present a case report of a woman for whom a topical mucosal ulcer drug was prescribed and the pharmacist erroneously dispensed a calcium channel blocker (CCB), resulting in toxicities from the drug and withdrawal symptoms when attempts were made to stop the CCB. The pharmacology and toxicology of CCBs are discussed, particularly in relation to the adverse experiences of the case.
O'Donnell
Rush Medical College, Chicago, IL, USA.
Mertl
S Y
SY
Kelly
W N
WN
D000328:Adult; D000368:Aged; D000818:Animals; D002121:Calcium Channel Blockers / Q000009:adverse effects*; D002764:Cholecystitis / Q000139:chemically induced; D003329:Coronary Vasospasm / Q000139:chemically induced; D004110:Diltiazem / Q000009:adverse effects*; D005260:Female; D005704:Gallbladder / Q000187:drug effects; D006801:Humans; D008297:Male; D019300:Medical Errors / Q000009:adverse effects*; D008875:Middle Aged; D011247:Pregnancy; D013375:Substance Withdrawal Syndrome / Q000209:etiology*; D019966:Substance-Related Disorders
D002121:Calcium Channel Blockers; D004110:Diltiazem