title: Prospective audit following the introduction of short-course preoperative radiotherapy for rectal cancer.
abstract: BACKGROUND
  The value of introducing a short course of preoperative radiotherapy before operation for rectal cancer is still subject to debate.
  
  
  METHODS
  One hundred consecutive patients, of mean age 68 (range 29-87) years undergoing pre- operative radiotherapy for rectal cancer between January 1997 and December 1998 at two radiotherapy centres were audited prospectively.
  
  
  RESULTS
  The time from referral to radiotherapy was 33 (11-74) days and from radiotherapy to operation 5 (1-42) days. There was a higher than expected anastomotic leak rate (15 per cent) and perineal wound infection rate (18 per cent). Patients waiting more than 7 days were more likely to suffer perineal wound breakdown: 15 per cent (n = 39) versus 30 per cent (n = 10).
  
  
  CONCLUSIONS
  The high anastomotic leak and perineal wound infection rates suggest that the introduction of preoperative radiotherapy combined with total mesorectal excision should be audited carefully or performed as part of the CRO7 trial. Presented to the Association of Coloproctology of Great Britain and Ireland in St Helier, Jersey, June 1998
authors.affiliation: University Department of Surgery, Northern General Hospital, Sheffield, UK.
authors.forename: S
authors.initials: S
authors.lastname: Lele
authors.forename: D
authors.initials: D
authors.lastname: Radstone
authors.forename: J
authors.initials: J
authors.lastname: Eremin
authors.forename: R
authors.initials: R
authors.lastname: Kendal
authors.forename: K B
authors.initials: KB
authors.lastname: Hosie
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care / Q000379:methods; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D016896:Treatment Outcome