title: Central mutation databases--a review.
abstract: The Internet has been a key component in the coordination of the diverse group of scientists involved in the Human Genome Project. Nowhere has this contribution been more critical than in the maintenance and exchange of information about genetic variation and mutation. Whereas the majority of DNA sequence is generated and stored by a relatively few sites, a far greater number of researchers investigate the variations in that sequence from sites scattered worldwide. It falls to central databases to utilize the Internet to assemble data from these sites and make them available to the greater human genomic community.
authors.affiliation: Johns Hopkins University, Baltimore, Maryland, USA.
authors.forename: C J
authors.initials: CJ
authors.lastname: Porter
authors.forename: C C
authors.initials: CC
authors.lastname: Talbot
authors.forename: A J
authors.initials: AJ
authors.lastname: Cuticchia
mesh_terms: D016208:Databases, Factual; D016045:Human Genome Project; D006801:Humans; D020407:Internet; D009154:Mutation; D020641:Polymorphism, Single Nucleotide