Aplysia gut epithelial cells: luminal membrane chloride channel activity.
The Cl(-) energy gradient across the luminal membrane of Aplysia foregut epithelial cells is directed downhill from the lumen to the cellular cytosol. No primary or secondary active transporters had been shown to be involved in Cl(-) translocation across the luminal membrane. Cl(-) channel blockers impeded the movement of Cl(-) from the lumen into the foregut cellular cytosol. It was concluded that the primary means of Cl(-) transport across the luminal membrane was via Cl(-) conductance.
Gerencser
G A
GA
Department of Physiology, College of Medicine, University of Florida, Gainesville, Florida 32610, USA.
D000818:Animals; D001048:Aplysia / Q000502:physiology*; D018118:Chloride Channels / Q000502:physiology*; D002712:Chlorides / Q000378:metabolism; D004064:Digestive System / Q000166:cytology; D004068:Digestive System Physiological Phenomena; D004847:Epithelial Cells / Q000502:physiology*; D005690:Galactose / Q000378:metabolism; D007413:Intestinal Mucosa / Q000378:metabolism; D012964:Sodium / Q000378:metabolism
D018118:Chloride Channels; D002712:Chlorides; D012964:Sodium; D005690:Galactose