title: Screening for cervical neoplasia by self-assessment for human papillomavirus DNA.
abstract: We evaluated self-collected vaginal human papillomavirus tests for cervical cancer screening and compared it with the specimens taken directly from the cervix in 247 patients at high-risk for cervical disease. The sample taken by the patient showed human papillomavirus DNA in a higher percentage than the sample taken by a doctor. Sensitivity of high-risk human papillomavirus types for high-grade cervical precursors (CIN 2/3) and invasive cervical cancers were 93% for both methods.
authors.forename: P
authors.initials: P
authors.lastname: Hillemanns
authors.forename: R
authors.initials: R
authors.lastname: Kimmig
authors.forename: U
authors.initials: U
authors.lastname: Hüttemann
authors.forename: C
authors.initials: C
authors.lastname: Dannecker
authors.forename: C J
authors.initials: CJ
authors.lastname: Thaler
mesh_terms: D001706:Biopsy; D003127:Colposcopy; D003475:Curettage; D004279:DNA, Viral / Q000032:analysis*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000295:instrumentation / Q000379:methods*; D009361:Neoplasm Invasiveness; D027383:Papillomaviridae / Q000235:genetics* / Q000302:isolation & purification; D011230:Precancerous Conditions / Q000175:diagnosis; D011446:Prospective Studies; D016353:Self-Examination; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000821:virology; D014626:Vaginal Smears / Q000295:instrumentation / Q000379:methods*; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis
chemical_list: D004279:DNA, Viral