title: [Time course of ventilatory drive in patients with kyphoscoliosis before and during intermittent ventilation].
abstract: The aim of this retrospective study was to investigate the mouth-occlusion-pressure under CO2-stimulation in five patients (3 women, 2 men) suffering from kyphoscoliosis of different aetiology whilst being under noninvasive ventilation for respiratory muscle fatigue. Ten months after initiation of noninvasive ventilation we could demonstrate a marginal improvement of respiratory muscle strength but the P0.1 CO2-decreased slightly. We conclude that this decrease might be due to an increase in tidal volume allowing for a reduction in respiratory rate.
authors.affiliation: Abteilung für Pneumologie, Allergologie und Schlafmedizin, Klinik Ambrock, Hagen.
authors.forename: F
authors.initials: F
authors.lastname: Feldmeyer
authors.forename: W
authors.initials: W
authors.lastname: Randerath
authors.forename: K H
authors.initials: KH
authors.lastname: Rühle
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D005621:Friedreich Ataxia / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D007384:Intermittent Positive-Pressure Breathing; D008297:Male; D008875:Middle Aged; D018763:Muscle Fatigue; D012132:Respiratory Muscles / Q000503:physiopathology; D014797:Vital Capacity