Improved canine model for laryngotracheal stenosis.
Laryngotracheal stenosis (LTS) is a serious challenge for the otolaryngologist. Although progress has been made in preventing and treating LTS, more research is required. Existing canine models for LTS incur high mortality and morbidity, require relatively complicated procedures or costly equipment, entail lengthy waiting periods, or have unpredictable results. A simple, reliable, and inexpensive procedure, requiring no tracheotomy, is described for creating a canine model for LTS research. The new improved model is compared with previous models described in the literature. It will be especially useful for short-term studies of subglottic or tracheal stenosis.
Eliashar
R
R
Department of Otolaryngology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Eliachar
I
I
Gramlich
T
T
Esclamado
R
R
Strome
M
M
D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D004724:Endoscopy; D007829:Laryngostenosis / Q000209:etiology / Q000473:pathology*; D014135:Tracheal Stenosis / Q000209:etiology / Q000473:pathology*