Cancer and the cell cycle.
The purpose of this short review is to provide an overview of mammalian somatic cell cycle events and their controls. Cell cycle-related studies have been under way for only 5% of this millennium, yet since then nearly 20,000 references have appeared. This vast literature cannot be detailed here, nor can fundamental information obtained with other organisms such as yeast and Xenopus, or topics such as the abbreviated cell cycle in early embryonic cells. (General references include Murray and Hunt [1993] The cell cycle, an introduction. New York: Oxford University Press, and Denhardt [1999] In: The molecular basis of cell cycle and growth control. p 225-304. New York: John Wiley & Sons, Inc.) J. Cell Biochem. Suppls. 32/33:166-172, 1999.
Ford
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Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
Pardee
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D000818:Animals; D002453:Cell Cycle; D002455:Cell Division; D016922:Cellular Senescence; D004247:DNA / Q000096:biosynthesis; D004249:DNA Damage / Q000235:genetics / Q000502:physiology; D006801:Humans; D009369:Neoplasms / Q000235:genetics / Q000473:pathology*
D004247:DNA