Screening of antibacterial activity of Amaicha del Valle (Tucumán, Argentina) propolis.
Propolis is extensively used in Argentine folk medicine. Alcoholic extracts of propolis from four localities of Amaicha del Valle (El Paraiso, La Banda Este, La Banda Oeste and El Molino), Province of Tucumán and from Cerrillos, Province of Santiago del Estero, Argentina were prepared. All showed antibacterial activity against Gram positive bacteria, the propolis from La Banda Este being the most active (MIC = 7.8 microg/ml) against Streptococcus piogenes, an antibiotic resistant bacterium. Thin layer chromatographic (TLC) separation profiles of propolis from Amaicha del Valle region were similar but differ from the alcoholic extract of the propolis from Cerrillos, another phytogeographical region of Argentina (provincia chaqueña). Bioautographic assays of the TLC profiles showed that several separated compounds of the Amaicha del Valle propolis have antibacterial activity. The difference in composition between Amaicha del Valle and Cerrillos propolis coincides with a different phytogeographical formation.
Nieva Moreno
M I
MI
Cátedra de Fitoquímica, Instituto de Estudios Vegetales, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Miguel de Tucumán, Argentina.
Isla
M I
MI
Cudmani
N G
NG
Vattuone
M A
MA
Sampietro
A R
AR
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001118:Argentina; D001345:Autoradiography; D002855:Chromatography, Thin Layer; D004353:Drug Evaluation, Preclinical; D004352:Drug Resistance, Microbial / Q000502:physiology; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008519:Medicine, Traditional; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D011429:Propolis / Q000737:chemistry*; D012995:Solubility; D013297:Streptococcus pyogenes / Q000187:drug effects
D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D011429:Propolis