title: Biochemopreventive therapy for patients with premalignant lesions of the head and neck and p53 gene expression.
authors.affiliation: Department of Thoracic/Head and Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Shin
authors.forename: L
authors.initials: L
authors.lastname: Mao
authors.forename: V M
authors.initials: VM
authors.lastname: Papadimitrakopoulou
authors.forename: G
authors.initials: G
authors.lastname: Clayman
authors.forename: A
authors.initials: A
authors.lastname: El-Naggar
authors.forename: H J
authors.initials: HJ
authors.lastname: Shin
authors.forename: J J
authors.initials: JJ
authors.lastname: Lee
authors.forename: J S
authors.initials: JS
authors.lastname: Lee
authors.forename: A
authors.initials: A
authors.lastname: Gillenwater
authors.forename: J
authors.initials: J
authors.lastname: Myers
authors.forename: S M
authors.initials: SM
authors.lastname: Lippman
authors.forename: W N
authors.initials: WN
authors.lastname: Hittelman
authors.forename: W K
authors.initials: WK
authors.lastname: Hong
mesh_terms: D016588:Anticarcinogenic Agents / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002471:Cell Transformation, Neoplastic / Q000187:drug effects* / Q000473:pathology; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects*; D006258:Head and Neck Neoplasms / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*; D006801:Humans; D007150:Immunohistochemistry; D016898:Interferon-alpha / Q000008:administration & dosage; D015474:Isotretinoin / Q000008:administration & dosage; D009154:Mutation / Q000187:drug effects*; D011230:Precancerous Conditions / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D011446:Prospective Studies; D016896:Treatment Outcome; D016159:Tumor Suppressor Protein p53 / Q000235:genetics / Q000378:metabolism*; D014810:Vitamin E / Q000008:administration & dosage
chemical_list: D016588:Anticarcinogenic Agents; D016898:Interferon-alpha; D016159:Tumor Suppressor Protein p53; D014810:Vitamin E; D015474:Isotretinoin