Familial primary cutaneous amyloidosis in a South African family.
Four members of a white South African family, spanning four generations were diagnosed as suffering from familial primary lichen amyloidosis. All showed similar clinical features which included scaling papules on the lower legs and arms, and a pebbled, lichenified appearance of the skin on the back. The diagnosis was confirmed by light and electron microscopy. This is the eleventh report of familial primary cutaneous amyloidosis and the first in South Africa.
Hartshorne
S T
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Division of Dermatology, Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa. vdhandel@iafrica.com
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000686:Amyloidosis / Q000235:genetics* / Q000473:pathology; D001706:Biopsy / Q000379:methods; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D010375:Pedigree; D012871:Skin Diseases / Q000235:genetics* / Q000473:pathology; D013019:South Africa