title: Paraneoplastic remitting seronegative symmetrical synovitis with pitting edema.
abstract: Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a syndrome that may be associated with many conditions, including malignancy. Three further cases of paraneoplastic RS3PE are described and the literature is reviewed. Paraneoplastic RS3PE is more frequently associated with solid tumors, in particular adenocarcinoma. The two clinical characteristics suggestive of paraneoplastic RS3PE are systemic sign/symptoms and the poor response to corticosteroid therapy.
authors.affiliation: Unità Reumatologica, Ospedale di Prato, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Cantini
authors.forename: C
authors.initials: C
authors.lastname: Salvarani
authors.forename: I
authors.initials: I
authors.lastname: Olivieri
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis; D000368:Aged; D004487:Edema / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D017809:Fatal Outcome; D005528:Foot / Q000473:pathology*; D005534:Foot Diseases / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D006225:Hand / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D012698:Serologic Tests; D012811:Sigmoid Neoplasms / Q000175:diagnosis; D013585:Synovitis / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D011241:Prednisone