Survival after massive ethylene glycol poisoning: role of an ethanol enriched, bicarbonate-based dialysate.
A 38-year old man presented with drowsiness 14 hours after ingesting about 1200 mls (40 ounces) of antifreeze in a suicide attempt. He was successfully treated with an ethanol enriched, bicarbonate based-dialysate. With a concomitant peripheral intravenous infusion of ethanol, this enrichment of the dialysate helped maintain the intradialytic ethanol concentration between 97-135 mg/dl over an 8 hour dialysis session. The patient developed acute tubular necrosis and required further dialysis. He made a complete recovery after three weeks and was discharged with a serum creatinine of 1.4 mg/dl.
Nzerue
C M
CM
Renal Service, Morehouse School of Medicine, Atlanta, Georgia 30310, USA.
Harvey
P
P
Volcy
J
J
Berdzenshvili
M
M
D000328:Adult; D001639:Bicarbonates / Q000008:administration & dosage*; D001786:Blood Glucose / Q000032:analysis; D015314:Dialysis Solutions; D000431:Ethanol / Q000008:administration & dosage* / Q000097:blood; D019855:Ethylene Glycol / Q000097:blood / Q000506:poisoning*; D006801:Humans; D008297:Male; D010758:Phosphorus / Q000097:blood; D006435:Renal Dialysis / Q000379:methods; D013406:Suicide, Attempted
D001639:Bicarbonates; D001786:Blood Glucose; D015314:Dialysis Solutions; D010758:Phosphorus; D000431:Ethanol; D019855:Ethylene Glycol