[Does tumor size influence the antioxidant defenses of the body].
A relationship between blood antioxidant status in patients with cervical tumors (T3NxM0) and size of primary tumor has been investigated. Enzymatic and non-enzymatic components of antioxidant defenses were most severely damaged in cases of large tumors which suggested a specific suppression of adaptation systems by malignancies. These findings make a case for further research in antioxidant therapy for cervical carcinoma with due consideration of pathogenetic features of tumor disease.
Rozenko
L Ia
LIa
Research Institute of Oncology, Rostov-on-Don.
Sidorenko
Iu S
IuS
Frantsiiants
E M
EM
D000975:Antioxidants / Q000378:metabolism* / Q000627:therapeutic use; D002374:Catalase / Q000097:blood; D003065:Coenzyme A / Q000097:blood; D005260:Female; D006801:Humans; D013482:Superoxide Dismutase / Q000097:blood; D002583:Uterine Cervical Neoplasms / Q000097:blood* / Q000201:enzymology / Q000473:pathology*; D014801:Vitamin A / Q000097:blood; D014810:Vitamin E / Q000097:blood
D000975:Antioxidants; D014801:Vitamin A; D014810:Vitamin E; D002374:Catalase; D013482:Superoxide Dismutase; D003065:Coenzyme A