[Drug treatment of gestational arterial hypertension in medical institutions of Russia (population study)].
OBJECTIVE
To evaluate current situation with administration of drugs against gestational arterial hypertension (GAH) in medical institutions of Russia.


METHODS
A population study in representative territories of European Russia has been performed to investigate current practice of GAH chemotherapy as compared to chronic arterial hypertension (CAH).


RESULTS
In spite of shorter duration, GAH treatment employed two times greater amount of medicines per a course than chemotherapy of CAH. Injections and infusions were practiced in GAH 4.6 and 4.3 times more frequently than in CAH, respectively. Most popular drugs for injection were spasmolytics dibasol, papaverin solution, magnesium sulphate solution, for oral administration--clonidin. Specific antihypertensive medicines and beta-blockers dominated in CAH; infusions, sedatives and diuretics were used less frequently. In GAH infusions of plasma substitutes was widely practiced without adequate antihypertensive treatment.


CONCLUSIONS
Management of pregnant women with hypertension overuses medicines. However, new effective antihypertensive medicines are not infrequently ignored. This fact can provoke further elevation of blood pressure and eventually result in preterm delivery. It is necessary to develop national standard of drug treatment of pregnant women with hypertension.
Supriaga
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D000047:Academies and Institutes; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D004232:Diuretics / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005865:Gestational Age; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000453:epidemiology; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D010276:Parasympatholytics / Q000627:therapeutic use*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy* / Q000453:epidemiology; D012426:Russia / Q000453:epidemiology; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D004232:Diuretics; D006993:Hypnotics and Sedatives; D010276:Parasympatholytics