[Dependence of the effectiveness of phage infection on energy status of staphylococcal cells].
Studies of phage infection efficiency in Staphylococcus aureus showed its dependence on the energy processes. Addition of KCN, dycyclohexylcarbodiimide and chlorocarbonylcyanide-phenylhydrazone at the moment of cells contact with bacteriophages lowered phagolysis efficiency to 49.5-68.0%. These inhibitors influenced on cell specifically leading to suppressing generators of protonmotive force and to dissipating membrane potential. Adding phages to the suspension of bacterial led to the dissipation of membrane potential.
Polishko
T N
TN
Dnepropetrovsk State University.
Vinnikov
A I
AI
D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone / Q000494:pharmacology; D004279:DNA, Viral; D004024:Dicyclohexylcarbodiimide / Q000494:pharmacology; D004734:Energy Metabolism; D008564:Membrane Potentials; D011190:Potassium Cyanide / Q000494:pharmacology; D013204:Staphylococcus Phages / Q000235:genetics / Q000502:physiology*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000821:virology*
D004279:DNA, Viral; D004024:Dicyclohexylcarbodiimide; D002258:Carbonyl Cyanide m-Chlorophenyl Hydrazone; D011190:Potassium Cyanide