title: Using consensus OPCRIT diagnoses. An efficient procedure for best-estimate lifetime diagnoses.
abstract: BACKGROUND
  The Operational Criteria Checklist (OPCRIT) generates diagnoses according to 12 operational diagnostic systems (e.g. DSM-III, DSM-III-R, Research Diagnostic Criteria, ICD-10).
  
  
  OBJECTIVE
  To examine the agreement between diagnoses generated by the OPCRIT, as completed by the interviewer, with a best-estimate lifetime procedure using the OPCRIT.
  
  
  METHODS
  Subjects came from large multi-generational bipolar or schizophrenia pedigrees (n = 100), and from a sample of unrelated subjects with schizophrenia (n = 40). We analysed the diagnostic agreement between OPCRIT diagnoses generated by the interviewer and our best-estimate OPCRIT diagnoses, according to DSM-III-R and ICD-10, using Cohen kappa statistics.
  
  
  RESULTS
  Excellent agreement was found between interviewer OPCRIT diagnoses and OPCRIT diagnoses made by the best-estimate lifetime consensus procedure for DSM-III-R (kappa = 0.83) and ICD-10 (kappa = 0.81).
  
  
  CONCLUSIONS
  Results suggest that this procedure for diagnostic assessment is an efficient alternative to classic best-estimate diagnosis procedures.
authors.affiliation: Department of Psychiatry, College of Medicine, Coimbra University, Portugal. helenamh@ci.uc.pt
authors.forename: M H
authors.initials: MH
authors.lastname: Azevedo
authors.forename: M J
authors.initials: MJ
authors.lastname: Soares
authors.forename: I
authors.initials: I
authors.lastname: Coelho
authors.forename: A
authors.initials: A
authors.lastname: Dourado
authors.forename: J
authors.initials: J
authors.lastname: Valente
authors.forename: A
authors.initials: A
authors.lastname: Macedo
authors.forename: M
authors.initials: M
authors.lastname: Pato
authors.forename: C
authors.initials: C
authors.lastname: Pato
mesh_terms: D000465:Algorithms; D001714:Bipolar Disorder / Q000175:diagnosis*; D006801:Humans; D015588:Observer Variation; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000175:diagnosis*; D012680:Sensitivity and Specificity