title: [Placebo-controlled dihydroepiandrosterone substitution in elderly men].
abstract: We evaluated the efficacy of dehydroepiandrosterone substitution in elderly men with erectile dysfunction. Fifty patients were randomly divided into two groups of 25 patients each. Group 1 was treated with a single oral dose of dehydroepiandrosterone (50 mg/day), whereas group 2 patients received a placebo. The International Index of Erectile Function was used to rate the success of this therapy. The patients in group 1 had a statistically significant increase in all domains of this index, in contrast to group 2 patients. Although our patient data are too small to perform a relevant statistical analysis, we believe that they represent a biologically obvious trend that justifies further extended studies.
authors.affiliation: Urologische Universitätsklinik, AKH Wien, Osterreich. Werner.Reiter@uro.akh.magwien.gv.at
authors.forename: W J
authors.initials: WJ
authors.lastname: Reiter
authors.forename: A
authors.initials: A
authors.lastname: Pycha
mesh_terms: D000284:Administration, Oral; D000368:Aged; D003687:Dehydroepiandrosterone / Q000008:administration & dosage* / Q000009:adverse effects; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D003687:Dehydroepiandrosterone