title: [Neonatal melanoma arising in a giant congenital nevus].
abstract: BACKGROUND
  Malignant melanoma arising in giant congenital nevus is a well known but rare event.
  
  
  METHODS
  A 15 day-old boy with giant congenital nevus all over the left leg was seen for a 6 mm red and bleeding nodule inside the nevus on the inner thigh. Histopathology showed spindle cell malignant melanoma. A 3 cm edge surgical excision was performed with a favorable outcome which persists 5 years later.
  
  
  CONCLUSIONS
  The diagnosis of malignant melanoma is always very difficult in a child, unless metastasis occurs. Histopathologic modifications of childhood malignant melanomas are discussed. Development of malignant melanoma in giant congenital nevus would not appear to exceed 5 p. 100. Nevertheless, early surgical excision is recommended because the nevus is smaller and skin mobilization is easier at this age.
authors.affiliation: Service de Dermatologie, Pr F. Cambazard, Hôpital Nord, Faculté de Médecine Jacques Lisfranc, CHU de St-Etienne, 42055 Saint-Etienne Cedex 02.
authors.forename: F
authors.initials: F
authors.lastname: Benoit-Durafour
authors.forename: J L
authors.initials: JL
authors.lastname: Michel
authors.forename: W
authors.initials: W
authors.lastname: Godard
authors.forename: V
authors.initials: V
authors.lastname: Chalencon
authors.forename: C
authors.initials: C
authors.lastname: Marzzocchi
authors.forename: F
authors.initials: F
authors.lastname: Chalencon
authors.forename: F
authors.initials: F
authors.lastname: Cambazard
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008545:Melanoma / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009506:Nevus / Q000151:congenital* / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*