How many mutations does it take to make a tumor?
Boland
C R
CR
Department of Medicine, University of California, San Diego, CA 92093-0688, USA. crboland@ucsd.edu
Ricciardiello
L
L
D018256:Adenomatous Polyps / Q000209:etiology / Q000235:genetics*; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D015179:Colorectal Neoplasms / Q000209:etiology / Q000235:genetics*; D006801:Humans; D019656:Loss of Heterozygosity; D008957:Models, Genetic; D009154:Mutation