Pancreatic carcinoma associated with chronic pancreatitis.
The incidence of invasive ductal carcinoma of the pancreas was 3.1% (6 cases) in 196 patients with definite chronic pancreatitis. Five patients (3 men and 2 women) had calcific pancreatitis and 1 patient (man) had non-calcific pancreatitis. Large pancreatic stones were recognized in 2 women. Most of the patients complained of continuous intractable abdominal pain and/or back pain together with weight loss and appetite loss. Serum CA19-9 levels and exacerbation of glucose intolerance were retrospectively noted to have been elevated in 1 patient. However, it was difficult to obtain a definitive diagnosis by imaging examinations earlier, due to the presence of chronic pancreatitis. Median survival of the 6 patients was 6.5 months from admission.
Wakasugi
H
H
Department of Gastroenterology, National Kyushu Cancer Center, Fukuoka.
Funakoshi
A
A
Iguchi
H
H
Takase
M
M
Inoue
M
M
Ohshima
A
A
Seo
Y
Y
D000230:Adenocarcinoma / Q000209:etiology*; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000209:etiology*; D010195:Pancreatitis / Q000150:complications*