title: Opsoclonus in a patient with cerebellar dysfunction.
abstract: After two days of malaise, headache, nausea, and vomiting, a 26-year-old man suddenly developed opsoclonus and stance and gait ataxia, without myoclonus. Having excluded a paraneoplastic etiology, we assumed that the disorder was probably related to a viral infection. Spontaneous resolution occurred in about two months. Opsoclonus became flutter dysmetria and then resolved. Saccadic eye movement recording disclosed the occurrence of hypermetria, increased velocity, and delayed latency, which also resolved. In this patient, the correspondence between clinical and ocular motor abnormality courses suggests a transient cerebellar dysfunction as the possible pathophysiologic mechanism for opsoclonus.
authors.affiliation: Dipartimento Scienze Neurologiche, Università di Pavia, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Versino
authors.forename: A
authors.initials: A
authors.lastname: Mascolo
authors.forename: G
authors.initials: G
authors.lastname: Piccolo
authors.forename: R
authors.initials: R
authors.lastname: Alloni
authors.forename: V
authors.initials: V
authors.lastname: Cosi
mesh_terms: D000328:Adult; D002524:Cerebellar Ataxia / Q000150:complications / Q000503:physiopathology; D002526:Cerebellar Diseases / Q000150:complications* / Q000503:physiopathology; D004569:Electroencephalography; D004585:Electrooculography; D005684:Gait; D006801:Humans; D008297:Male; D015835:Ocular Motility Disorders / Q000209:etiology* / Q000503:physiopathology; D012438:Saccades