title: Helicases as nucleic acid unwinding machines.
abstract: Nucleic acid unwinding is an essential step in many biomolecular processes. Researchers in this field recently met to examine progress and outstanding issues.
authors.affiliation: Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, 660 South Euclid Ave., Saint Louis, Missouri 63130, USA. waksman@biochem.wustl.edu
authors.forename: G
authors.initials: G
authors.lastname: Waksman
authors.forename: E
authors.initials: E
authors.lastname: Lanka
authors.forename: J M
authors.initials: JM
authors.lastname: Carazo
mesh_terms: D020029:Base Pairing / Q000235:genetics*; D001665:Binding Sites; D018360:Crystallography, X-Ray; D004265:DNA Helicases / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D008854:Microscopy, Electron; D008958:Models, Molecular; D020409:Molecular Motor Proteins / Q000737:chemistry / Q000378:metabolism; D019906:Nuclear Magnetic Resonance, Biomolecular; D009696:Nucleic Acids / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D011487:Protein Conformation; D020365:RNA Helicases / Q000737:chemistry* / Q000378:metabolism*; D013329:Structure-Activity Relationship
chemical_list: D020409:Molecular Motor Proteins; D009696:Nucleic Acids; D004265:DNA Helicases; D020365:RNA Helicases