title: Establishment of a persistent mutant of canine distemper virus.
abstract: We produced a B95a lymphoid cell line persistently infected with canine distemper virus (CDV), in which virus-specific antigens were present in nearly 100% of cells without causing cytopathic effect. The virus recovered from this cell line was able to infect fresh B95a cells persistently, indicating that a persistent CDV was established.
authors.affiliation: Department of Veterinary Microbiology, Graduate School of Agricultural and Science, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Iwatsuki
authors.forename: Y
authors.initials: Y
authors.lastname: Ikeda
authors.forename: K
authors.initials: K
authors.lastname: Ohashi
authors.forename: K
authors.initials: K
authors.lastname: Nakamura
authors.forename: C
authors.initials: C
authors.lastname: Kai
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001402:B-Lymphocytes / Q000166:cytology / Q000821:virology*; D002460:Cell Line; D004216:Distemper / Q000821:virology; D004217:Distemper Virus, Canine / Q000235:genetics* / Q000254:growth & development*; D004285:Dogs; D006389:Hemagglutinins, Viral / Q000737:chemistry / Q000235:genetics; D008969:Molecular Sequence Data; D009154:Mutation; D014760:Viral Fusion Proteins / Q000737:chemistry / Q000235:genetics; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics
chemical_list: D006389:Hemagglutinins, Viral; D014760:Viral Fusion Proteins; D014764:Viral Proteins