title: Doppler flowmetry in the differentiation of biological characteristics of ovarian cancer.
abstract: On basis of ultrasonographic structural criteria and Doppler flowmetry in a group of 76 patients with ovarian cancer, benign lesions were discovered in 59 patients and malignant lesions in 17 patients (77.6% and 22.4%, respectively). Surgical intervention was indicated according to the clinical findings and following of the trend of organ-specific oncomarkers in 32 out of 76 patients (42.1%). The stratification involved 17 patients with sonomorphologically/Doppler-flowmetry - diagnosed malignancy as well as 15 patients with sonographically diagnosed benign ovarian tumor. The clinical findings were histologically verified in all 32 patients. Histology confirmed malignant tumor in 16 patients, 1 histologically borderline malignancy and 15 benign tumors. The Doppler-flowmetry showed 94.1% sensitivity, 93.3% specificity, 93.3% positive predictive value, and 93.75% accuracy.
authors.affiliation: Clinic of Oncology, Faculty of Medicine, Comenius University, Bratislava, Slovak Republic.
authors.forename: V
authors.initials: V
authors.lastname: Lehotská
authors.forename: J
authors.initials: J
authors.lastname: Svec
authors.forename: A
authors.initials: A
authors.lastname: Durkovský
authors.forename: A
authors.initials: A
authors.lastname: Suhajdová
authors.forename: L
authors.initials: L
authors.lastname: Sevcíková
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D003537:Cystadenoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008875:Middle Aged; D018294:Neoplasms, Adnexal and Skin Appendage / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D010048:Ovarian Cysts / Q000000981:diagnostic imaging; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014463:Ultrasonography
chemical_list: D014408:Biomarkers, Tumor