title: The gene for human transcription factor TCF11 is located telomeric to D17S1827, BTR and HP1Hsbeta on chromosome 17q22.
abstract: We report the screening of thirty-one YACs with a number of markers using polymerase chain reaction (PCR) to construct a physical map of part of human chromosome 17q21.3-q22. A contig of YACs covering about 4 Mb was constructed around the TCF11 gene at 68 cM from the most telomeric marker on the p arm, localizing TCF11 telomeric to genetic marker D17S1827. Both human and mouse P1-derived artificial chromosomes (PACs) containing TCF11 were isolated and characterized. The human heterochromatin protein 1 gene, HP1Hsbeta, and its homologue in mouse, MoMOD1, were identified centromeric to TCF11.
authors.affiliation: Biotechnology Centre of Oslo, University of Oslo, Norway.
authors.forename: N
authors.initials: N
authors.lastname: Skammelsrud
authors.forename: E R
authors.initials: ER
authors.lastname: Martin
authors.forename: P
authors.initials: P
authors.lastname: Murphy
authors.forename: C
authors.initials: C
authors.lastname: Khuu
authors.forename: E
authors.initials: E
authors.lastname: Frengen
authors.forename: A B
authors.initials: AB
authors.lastname: Kolstø
mesh_terms: D000818:Animals; D018244:Chromosomes, Artificial, Yeast; D002886:Chromosomes, Human, Pair 17; D020451:Contig Mapping; D005091:Exons; D006801:Humans; D016350:Leucine Zippers; D051379:Mice; D008969:Molecular Sequence Data; D051265:NF-E2-Related Factor 1; D020161:Physical Chromosome Mapping; D015183:Restriction Mapping; D016415:Sequence Alignment; D016615:Telomere; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D051265:NF-E2-Related Factor 1; C088357:NFE2L1 protein, human; D014157:Transcription Factors