title: The heparin management test: a new device for monitoring anticoagulation during coronary intervention.
abstract: Whole blood coagulation analysers are widely used during percutaneous coronary interventions. The precise degree of anticoagulation in patients is important in this setting. The aim of this investigation was to compare the results obtained with ACT (Hemochron) and HMT, the Heparin Management Test (TAS) in patients undergoing percutaneous coronary interventions. Patients (n = 100) were enrolled prospectively. Each patient received 10,000 units of heparin. At the end of the procedure, the mean ACT was 284+/-31 seconds and the mean HMT was 292+/-33 seconds. The correlation between the two methods was highly significant (r = 0.64, p<0.001). The HMT correlates well with ACT values in patients undergoing percutaneous coronary interventions. Its use in the management of these patients should be considered.
authors.affiliation: Clinique de Cardiologie, Hôpital Necker, Paris, France. helftg01@doc.mssm.edu
authors.forename: G
authors.initials: G
authors.lastname: Helft
authors.forename: P
authors.initials: P
authors.lastname: Bartolomeo
authors.forename: A G
authors.initials: AG
authors.lastname: Zaman
authors.forename: S G
authors.initials: SG
authors.lastname: Worthley
authors.forename: S
authors.initials: S
authors.lastname: Chokron
authors.forename: C
authors.initials: C
authors.lastname: Le Pailleur
authors.forename: F
authors.initials: F
authors.lastname: Beygui
authors.forename: C
authors.initials: C
authors.lastname: Le Feuvre
authors.forename: J P
authors.initials: JP
authors.lastname: Metzger
authors.forename: A
authors.initials: A
authors.lastname: Vacheron
authors.forename: M M
authors.initials: MM
authors.lastname: Samama
mesh_terms: D000789:Angina, Unstable / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary; D000925:Anticoagulants / Q000627:therapeutic use*; D001777:Blood Coagulation / Q000187:drug effects*; D001780:Blood Coagulation Tests / Q000295:instrumentation*; D016903:Drug Monitoring / Q000379:methods*; D005069:Evaluation Studies as Topic; D005260:Female; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D007275:Injections, Intravenous; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015203:Reproducibility of Results; D014914:Whole Blood Coagulation Time
chemical_list: D000925:Anticoagulants; D006493:Heparin