title: Stabilizing effect of posterior lumbar interbody fusion cages before and after cyclic loading.
abstract: OBJECTIVE
  The function of interbody fusion cages is to stabilize spinal segments primarily by distracting them as well as by allowing bone ingrowth and fusion. An important condition for efficient formation of bone tissue is achieving adequate spinal stability. However, the initial stability may be reduced due to repeated movements of the spine during everyday activity. Therefore, in addition to immediate stability, stability after cyclic loading is of remarkable relevance; however, this has not yet been investigated. The object of this study was to investigate the immediate stabilizing effect of three different posterior lumbar interbody fusion cages and to clarify the effect of cyclic loading on the stabilization.
  
  
  METHODS
  Before and directly after implantation of a Zientek, Stryker, or Ray posterior lumbar interbody fusion cage, 24 lumbar spine segment specimens were each evaluated in a spine tester. Pure lateral bending, flexion-extension, and axial rotation moments (+/- 7.5 Nm) were applied continuously. The motion in each specimen was measured simultaneously. The specimens were then loaded cyclically (40,000 cycles, 5 Hz) with an axial compression force ranging from 200 to 1000 N. Finally, they were tested once again in the spine tester.
  
  
  CONCLUSIONS
  In general, a decrease of movement in all loading directions was noted after insertion of the Zientek and Ray cages and an increase of movement after implantation of a Stryker cage. In all three cage groups greater stability was demonstrated in lateral bending and flexion than in extension and axial rotation. Reduced stability during cyclic loading was observed in all three cage groups; however, loss of stability was most pronounced when the Ray cage was used.
authors.affiliation: Institute for Orthopaedic Research and Biomechanics, University of Ulm, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Kettler
authors.forename: H J
authors.initials: HJ
authors.lastname: Wilke
authors.forename: R
authors.initials: R
authors.lastname: Dietl
authors.forename: M
authors.initials: M
authors.lastname: Krammer
authors.forename: C
authors.initials: C
authors.lastname: Lumenta
authors.forename: L
authors.initials: L
authors.lastname: Claes
mesh_terms: D005080:Exercise Test; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000502:physiology*; D008297:Male; D009038:Motion; D012044:Regression Analysis; D013123:Spinal Fusion / Q000295:instrumentation*; D018709:Statistics, Nonparametric