Assessment of optic nerve damage in multiple sclerosis using magnetic resonance imaging.
The MR imaging-based assessment of the optic nerve in optic neuritis and multiple sclerosis provides information that is complementary to clinical and electrophysiological methods. The standard and more tissue destruction specific methods can be used in strategies to measure treatment efficacy and for understanding the mechanisms of relapse, recovery, and failure of recovery.
Simon
J H
JH
Department of Radiology/MRI, University of Colorado Health Sciences Center, 4200 E Ninth Ave, Denver, CO, USA. jack.simon@uchsc.edu
McDonald
W I
WI
D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009103:Multiple Sclerosis / Q000473:pathology* / Q000628:therapy; D009901:Optic Nerve Diseases / Q000473:pathology* / Q000628:therapy; D009902:Optic Neuritis / Q000473:pathology / Q000628:therapy