[Neurocysticercosis in the South-East of France 1988-1998].
OBJECTIVE
Neurocysticercosis is commonly observed in developing countries but can also occur in industrialized countries. The aim of this work was to analyze diagnostic and therapeutic data on cases of neurocysticercosis diagnosed in southeastern France over the last 10 years.


METHODS
We collected data from patient files and compared them with those reported in the literature.


RESULTS
We collected 29 cases of neurocysticercosis diagnosed in southeastern France between 1988 and 1999. None of the patients had acquired the disease in France. Seizures were the most common inaugural sign. Four patients had skin lesions and very few had radiologically identifiable muscle calcifications. CT scan and MRI provided the diagnosis of neurocysticercosis and contributed to follow-up. Brain imaging showed cyst formation and calcifications. Cysticercosis serology was positive in only 52% of our patients. Antiparasite treatments with albendazole provided improvement in most patients although aggravation was observed in 4 despite a well-conducted regimen. There was one death.


CONCLUSIONS
Neurological manifestations, particularly seizures, in a patient returning from an endemic zone should prompt search for neurocysticercosis with brain CT and MRI. Regression of clinical and radiological signs with treatment confirms the diagnosis.
Rousseau
M C
MC
Service de Maladies Infectieuses et Tropicales, CHU Houphouet-Boigny, Marseille.
Guillotel
B
B
Delmont
J
J
D005260:Female; D005602:France / Q000453:epidemiology; D049673:History, 20th Century; D006801:Humans; D008297:Male; D020019:Neurocysticercosis / Q000453:epidemiology* / Q000266:history