Human cortical regions involved in extracting depth from motion.
We used functional magnetic resonance imaging (fMRI) to investigate brain regions involved in extracting three-dimensional structure from motion. A factorial design included two-dimensional and three-dimensional structures undergoing rigid and nonrigid motions. As predicted from monkey data, the human homolog of MT/V5 was significantly more active when subjects viewed three-dimensional (as opposed to two-dimensional) displays, irrespective of their rigidity. Human MT/V5+ (hMT/V5+) is part of a network with right hemisphere dominance involved in extracting depth from motion, including a lateral occipital region, five sites along the intraparietal sulcus (IPS), and two ventral occipital regions. Control experiments confirmed that this pattern of activation is most strongly correlated with perceived three-dimensional structure, in as much as it arises from motion and cannot be attributed to numerous two-dimensional image properties or to saliency.
Orban
G A
GA
Katholieke Universiteit te Leuven, Faculty of Medicine, Laboratorium voor Neuro- en Psychofysiologie, Leuven, Belgium. guy.orban@med.kuleuven.ac.be
Sunaert
S
S
Todd
J T
JT
Van Hecke
P
P
Marchal
G
G
D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D003867:Depth Perception / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D009039:Motion Perception / Q000502:physiology*; D010775:Photic Stimulation; D012399:Rotation; D012858:Size Perception / Q000502:physiology; D014793:Visual Cortex / Q000502:physiology*