title: Fixation, polyethylene wear, and pelvic osteolysis in primary total hip replacement.
abstract: A multicenter retrospective review was performed analyzing 1081 primary total hip replacements in 944 patients using the Harris Galante-I cementless acetabular component with screw fixation. All patients were followed up for a minimum of 5 years with a mean followup of 81 months. Linear polyethylene wear averaged 0.11 mm/year (range, 0-0.86 mm/year). Pelvic osteolysis was seen in 25 patients (2.3%). Migration of the acetabular component was seen in four hips. A subgroup of patients was reanalyzed at a minimum followup of 10 years. The mean linear polyethylene wear rate remained 0.11 mm/year. In this group, only one socket had migrated. There was an association between wear rate and age. On average, younger patients had higher wear rates. The risk for having pelvic osteolysis develop and the need for revision surgery also was age-related. Twenty-two percent of hip replacements (15 hips) in patients younger than 50 years of age at the time of their index operation had pelvic osteolysis develop. In contrast, for patients older than 50 years of age at the time of surgery only 7.8% (eight hips) had osteolysis of the pelvis develop. For patients older than 70 years of age at the time of primary total hip replacement, none had pelvic osteolysis develop.
authors.affiliation: Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Maloney
authors.forename: J O
authors.initials: JO
authors.lastname: Galante
authors.forename: M
authors.initials: M
authors.lastname: Anderson
authors.forename: V
authors.initials: V
authors.lastname: Goldberg
authors.forename: W H
authors.initials: WH
authors.lastname: Harris
authors.forename: J
authors.initials: J
authors.lastname: Jacobs
authors.forename: M
authors.initials: M
authors.lastname: Kraay
authors.forename: P
authors.initials: P
authors.lastname: Lachiewicz
authors.forename: H E
authors.initials: HE
authors.lastname: Rubash
authors.forename: S
authors.initials: S
authors.lastname: Schutzer
authors.forename: S T
authors.initials: ST
authors.lastname: Woolson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006621:Hip Joint / Q000000981:diagnostic imaging; D006622:Hip Prosthesis / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000209:etiology*; D010384:Pelvic Bones / Q000000981:diagnostic imaging; D020959:Polyethylene / Q000737:chemistry*; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000209:etiology*; D011474:Prosthesis Design; D011475:Prosthesis Failure; D011859:Radiography; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D020959:Polyethylene