title: Scrotal hematoma, anemia, and jaundice as manifestations of adrenal neuroblastoma in a newborn.
abstract: Clinically, a neuroblastoma presents mostly as an abdominal mass. Within the tumor, bleeding can be present, sometimes extending in to its surroundings. This case report describes a neuroblastoma, presenting as scrotal hematoma in a newborn boy, which initially raised the suspicion of a torsion testis. In this patient, the bleeding descended through the subcutaneous and muscular tissue into the scrotum. In addition, anemia and jaundice were marked features. This clinical manifestation of a neuroblastoma has not been reported previously. Ultrasonography is advised as the first diagnostic step to exclude retroperitoneal origin of the bleeding. Magnetic resonance imaging and meta-iodobenzyl guanidine scanning were helpful tools in the final diagnostic workup.
authors.affiliation: Department of Surgery, University Hospital Groningen, The Netherlands.
authors.forename: H G
authors.initials: HG
authors.lastname: Kreeftenberg
authors.forename: C J
authors.initials: CJ
authors.lastname: Zeebregts
authors.forename: R Y
authors.initials: RY
authors.lastname: Tamminga
authors.forename: Z J
authors.initials: ZJ
authors.lastname: de Langen
authors.forename: R J
authors.initials: RJ
authors.lastname: Zijlstra
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000740:Anemia / Q000209:etiology*; D005832:Genital Diseases, Male / Q000209:etiology*; D006406:Hematoma / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D009447:Neuroblastoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D012611:Scrotum