title: Thrombosis in a duplicated superficial femoral vein in a patient with haemophilia A.
abstract: Venous thrombosis is a very rare occurrence in patients with haemophilia A. We report the case of a haemophiliac in whom initially a calf haematoma was suspected, but neither this nor deep venous thrombosis (DVT) could be confirmed on ultrasound scanning. Subsequently, a high segment venous thrombosis was diagnosed by venography in a portion of a duplicated superficial femoral vein. Treatment with factor VIII (FVIII) and low molecular weight heparin led to a successful resolution. The only other case we have been able to find in the literature occurred during FVIII replacement therapy, which was not the situation with our patient.
authors.affiliation: Department of Haematology, Royal Infirmary of Edinburgh, Edinburgh, UK.
authors.forename: A J
authors.initials: AJ
authors.lastname: Stewart
authors.forename: L M
authors.initials: LM
authors.lastname: Manson
authors.forename: R
authors.initials: R
authors.lastname: Dennis
authors.forename: P L
authors.initials: PL
authors.lastname: Allan
authors.forename: C A
authors.initials: CA
authors.lastname: Ludlam
mesh_terms: D000328:Adult; D005169:Factor VIII / Q000008:administration & dosage; D005268:Femoral Vein / Q000002:abnormalities* / Q000473:pathology; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006467:Hemophilia A / Q000097:blood / Q000150:complications* / Q000628:therapy; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage; D006801:Humans; D007866:Leg; D008297:Male; D010146:Pain; D012307:Risk Factors; D018805:Sepsis / Q000188:drug therapy; D000078222:Tinzaparin; D014195:Travel; D020246:Venous Thrombosis / Q000097:blood / Q000150:complications* / Q000209:etiology*
chemical_list: D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D000078222:Tinzaparin; D005169:Factor VIII