title: Light-induced fluorescence endoscopy of the gastrointestinal tract.
abstract: The early detection of dysplasia and superficial malignant lesions of the gastrointestinal tract is of significant clinical importance. Recent advances in fluorescence-based endoscopic imaging and spectroscopy of the gastrointestinal tract may offer alternative means of detecting and identifying premalignant and malignant lesions that were otherwise occult or nonspecific on conventional white-light endoscopy. The purpose of this article is to present a general overview of the current developments and possible clinical roles of light-induced fluorescence endoscopy as an adjunct to routine diagnostic endoscopy to enhance screening and surveillance for premalignant and malignant gastrointestinal lesions.
authors.affiliation: Department of Medical Biophysics, University of Toronto, Ontario Cancer Institute, Toronto, Ontario, Canada.
authors.forename: R S
authors.initials: RS
authors.lastname: DaCosta
authors.forename: B C
authors.initials: BC
authors.lastname: Wilson
authors.forename: N E
authors.initials: NE
authors.lastname: Marcon
mesh_terms: D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005453:Fluorescence; D005456:Fluorescent Dyes; D006801:Humans; D007414:Intestinal Neoplasms / Q000175:diagnosis / Q000517:prevention & control; D007422:Intestines / Q000473:pathology; D008027:Light; D008403:Mass Screening; D011230:Precancerous Conditions / Q000175:diagnosis / Q000517:prevention & control; D013050:Spectrometry, Fluorescence; D013270:Stomach / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000517:prevention & control
chemical_list: D005456:Fluorescent Dyes