title: [Parvovirus B19 infection--an insidious chameleon].
abstract: Parvovirus B19 is a common source of infection with a seroprevalence of 60-70 per cent in the adult population. The most common manifestation is erythema infectiosum ('fifth disease'), with exanthem, fever and upper airway symptoms in children. The infection can give rise to a multifacetted clinical picture and is probably underdiagnosed, particularly in risk groups (individuals with haemolytic anaemia or immunosuppression, and fetuses). Serological diagnosis can now be complemented with the demonstration of viral DNA using the PCR (polymerase chain reaction) test in various body fluids, or tissue biopsy. Recent years have witnessed manifest increase in clinical knowledge of parvovirus B19-associated complications, and their diagnosis and treatment.
authors.affiliation: Kliniskt virologiska laboratoriet, Karolinska institutet.
authors.forename: K
authors.initials: K
authors.lastname: Broliden
authors.forename: T
authors.initials: T
authors.lastname: Tolfvenstam
authors.forename: N
authors.initials: N
authors.lastname: Papadogiannakis
authors.forename: M
authors.initials: M
authors.lastname: Westgren
authors.forename: P
authors.initials: P
authors.lastname: Matt
authors.forename: A
authors.initials: A
authors.lastname: Lundqvist
authors.forename: L
authors.initials: L
authors.lastname: Skjöldebrand-Sparre
authors.forename: M
authors.initials: M
authors.lastname: Nyman
authors.forename: J I
authors.initials: JI
authors.lastname: Henter
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D004279:DNA, Viral / Q000032:analysis; D016731:Erythema Infectiosum / Q000175:diagnosis / Q000235:genetics / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D010322:Parvoviridae Infections / Q000175:diagnosis / Q000235:genetics / Q000276:immunology; D016732:Parvovirus B19, Human / Q000235:genetics / Q000276:immunology; D010920:Placenta / Q000473:pathology / Q000821:virology; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000276:immunology / Q000821:virology*
chemical_list: D004279:DNA, Viral