Screening for cervical neoplasia by self-assessment for human papillomavirus DNA.
We evaluated self-collected vaginal human papillomavirus tests for cervical cancer screening and compared it with the specimens taken directly from the cervix in 247 patients at high-risk for cervical disease. The sample taken by the patient showed human papillomavirus DNA in a higher percentage than the sample taken by a doctor. Sensitivity of high-risk human papillomavirus types for high-grade cervical precursors (CIN 2/3) and invasive cervical cancers were 93% for both methods.
Hillemanns
P
P
Kimmig
R
R
Hüttemann
U
U
Dannecker
C
C
Thaler
C J
CJ
D001706:Biopsy; D003127:Colposcopy; D003475:Curettage; D004279:DNA, Viral / Q000032:analysis*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000295:instrumentation / Q000379:methods*; D009361:Neoplasm Invasiveness; D027383:Papillomaviridae / Q000235:genetics* / Q000302:isolation & purification; D011230:Precancerous Conditions / Q000175:diagnosis; D011446:Prospective Studies; D016353:Self-Examination; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000821:virology; D014626:Vaginal Smears / Q000295:instrumentation / Q000379:methods*; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis
D004279:DNA, Viral