title: Extensive genetic polymorphism of peptidases A, B, C, and D, in wild rabbit (Oryctolagus cuniculus) populations from the Iberian Peninsula.
abstract: Genetic polymorphism of peptidases A, B, C, and D in the wild rabbit (Oryctolagus cuniculus) was assessed by horizontal starch gel electrophoresis, in a total of 1003 individuals comprising 16 Iberian and 2 French populations and 1 domestic stock. Twenty-five different alleles were detected: 6 in PEPA, 4 in PEPB, 8 in PEPC, and 7 in PEPD. The highest values of observed heterozygosity averaged over the four loci were obtained for the southwestern Iberian populations and a clinal loss of variability in a northeastern direction was detected. A clear separation between the two putative subspecies O. c. cuniculus and O. c. algirus was not obtained.
authors.affiliation: Departamento Zoologia e Antropologia, Faculdade de Ciências, Universidade do Porto, Portugal. msbranco@fc.up.pt
authors.forename: M
authors.initials: M
authors.lastname: Branco
authors.forename: J C
authors.initials: JC
authors.lastname: Machado
authors.forename: N
authors.initials: N
authors.lastname: Ferrand
mesh_terms: D000483:Alleles; D000626:Aminopeptidases / Q000235:genetics*; D000818:Animals; D000835:Animals, Wild / Q000235:genetics / Q000378:metabolism; D016282:Aspartic Acid Endopeptidases / Q000235:genetics*; D004150:Dipeptidases / Q000235:genetics*; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; D005602:France; D005787:Gene Frequency; D005828:Genetics, Population; D006579:Heterozygote; D010447:Peptide Hydrolases / Q000235:genetics*; D011110:Polymorphism, Genetic; D011174:Portugal; D011817:Rabbits / Q000235:genetics* / Q000378:metabolism*; D013030:Spain
chemical_list: D010447:Peptide Hydrolases; C037529:peptidase C; D000626:Aminopeptidases; C026045:tripeptide aminopeptidase; D004150:Dipeptidases; C022449:proline dipeptidase; D004152:Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; C022325:aspartic proteinase A; D016282:Aspartic Acid Endopeptidases