title: Evaluation of microvascular anatomy by micro-CT.
abstract: Observations indicate that adventitial vasa vasorum may play a role in the development and/or the progression of coronary atherosclerosis. There is a lack of information regarding the spatial three-dimensional pattern of the vasa vasorum in the coronary artery. This is due to the technical difficulties in visualizing the course of this fine vascular network with histologic methods. Microscopic computed tomography (micro-CT) is a novel technique that allows three-dimensional views of the entire microvascular structure. The current review summarizes our current advances in using this technique in visualization of the coronary circulation.
authors.affiliation: Department of Physiology & Biophysics, Mayo Clinic and Foundation, Rochester, Minnesota, USA. lerman.amir@mayo.edu
authors.forename: A
authors.initials: A
authors.lastname: Lerman
authors.forename: E L
authors.initials: EL
authors.lastname: Ritman
mesh_terms: D000818:Animals; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000473:pathology; D003331:Coronary Vessels / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008833:Microcirculation / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014651:Vasa Vasorum / Q000473:pathology