title: Struvite stones: diagnosis and current treatment concepts.
abstract: Effective management of struvite calculi requires a comprehensive approach to eliminate the stone burden and prevent stone recurrence. These stones occur more frequently in women, infants, and the elderly, as these patients are at greater risk for urinary tract infections. All patients should have routine laboratory testing as well as an excretory urogram. Appropriate urine cultures should be completed. Definitive management should promptly follow diagnosis. Percutaneous nephrolithotomy with or without SWL is the usual treatment. Appropriate antibiotic use is helpful; magnesium and phosphorus restriction and administration of urease inhibitors are less valuable.
authors.affiliation: Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors.forename: M T
authors.initials: MT
authors.lastname: Gettman
authors.forename: J W
authors.initials: JW
authors.lastname: Segura
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004724:Endoscopy; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006801:Humans; D007669:Kidney Calculi / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism / Q000601:surgery / Q000628:therapy*; D008096:Lithotripsy; D017616:Magnesium Compounds / Q000378:metabolism*; D010710:Phosphates / Q000378:metabolism*; D000069877:Struvite; D014510:Urease / Q000037:antagonists & inhibitors; D018666:Ureteroscopy; D014572:Urology / Q000639:trends*
chemical_list: D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D017616:Magnesium Compounds; D010710:Phosphates; D000069877:Struvite; D014510:Urease