Prenatal detection of cerebral lesions in a fetus with tuberous sclerosis.
We report a newborn, diagnosed prenatally with both cardiac rhabdomyomas and a brain tumor. To the best of our knowledge, this is the first report of central nervous system (CNS) lesions detected prenatally in a child with tuberous sclerosis with term follow-up. At 36 months, the child has normal growth and is developing appropriately. Thus the finding of CNS tumors on fetal ultrasound examination can help in the prenatal diagnosis of tuberous sclerosis but does not necessarily indicate a poor prognosis.
Sgro
M
M
Department of Pediatrics, Toronto Hospital-General Division, University of Toronto, Ontario, Canada.
Barozzino
T
T
Toi
A
A
Johnson
J
J
Sermer
M
M
Chitayat
D
D
D000328:Adult; D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D004452:Echocardiography; D004453:Echoencephalography; D005260:Female; D005500:Follow-Up Studies; D006338:Heart Neoplasms / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging; D011247:Pregnancy; D012207:Rhabdomyoma / Q000000981:diagnostic imaging; D014402:Tuberous Sclerosis / Q000000981:diagnostic imaging*; D016216:Ultrasonography, Prenatal