title: Antiurolithiatic activity of Raphanus sativus aqueous extract on rats.
abstract: The aqueous extract of the bark of Raphanus sativus was tested for its antiurolithiatic and diuretic activity. The urolithiasis was experimentally induced by implantation of zinc disc in the urinary bladder of rats. Significant decrease in the weight of stones was observed after treatment in animals which received aqueous extract in comparison with control groups. This extract showed an increase in the 24 h urine volume as compared to the control.
authors.affiliation: Departamento de Sistemas Biologicos, Universidad Autónoma Metropolitana-Xochimilco, Mexico D.F., Mexico.
authors.forename: R
authors.initials: R
authors.lastname: Vargas
authors.forename: R M
authors.initials: RM
authors.lastname: Perez
authors.forename: S
authors.initials: S
authors.lastname: Perez
authors.forename: M A
authors.initials: MA
authors.lastname: Zavala
authors.forename: C
authors.initials: C
authors.lastname: Perez
mesh_terms: D000818:Animals; D004232:Diuretics / Q000494:pharmacology*; D005260:Female; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D012995:Solubility; D013997:Time Factors; D001743:Urinary Bladder / Q000187:drug effects*; D014545:Urinary Calculi / Q000188:drug therapy*; D014867:Water / Q000737:chemistry; D015032:Zinc / Q000633:toxicity
chemical_list: D004232:Diuretics; D010936:Plant Extracts; D014867:Water; D015032:Zinc