title: Coding sequence evolution.
abstract: Dramatic progress has been made in the past ten years in the development of statistical and experimental techniques for investigating features of molecular evolution. Applied to coding regions, these techniques have produced remarkable advances in our understanding of selection for codon usage but, ironically, have had little impact on our understanding of protein evolution. That may be about to change.
authors.affiliation: Department of Ecology and Evolution, University of Chicago, Chicago, 60637, USA. mkre@midway.uchicago.edu
authors.forename: M
authors.initials: M
authors.lastname: Kreitman
authors.forename: J M
authors.initials: JM
authors.lastname: Comeron
mesh_terms: D000818:Animals; D003062:Codon / Q000235:genetics*; D019143:Evolution, Molecular; D005815:Genetic Code / Q000235:genetics*; D006801:Humans; D008957:Models, Genetic; D009154:Mutation / Q000235:genetics; D016366:Open Reading Frames / Q000235:genetics*; D011506:Proteins / Q000737:chemistry / Q000235:genetics; D011995:Recombination, Genetic; D012641:Selection, Genetic
chemical_list: D003062:Codon; D011506:Proteins