title: Intestinal stoma complications in immunocompromised children.
abstract: OBJECTIVE
  When performing an urgent gastrointestinal operation on an immunocompromised child, the pediatric surgeon may have to decide between performing an intestinal anastomosis (and risk leakage or sepsis) or creating an intestinal stoma. This study evaluates the postoperative course of those patients treated with intestinal stomas and the long-term survival rate of such patients.
  
  
  METHODS
  A 13-year retrospective review of immunocompromised children with intestinal stomas was performed. Patients were assessed as to their diagnosis, indication for surgery, stoma type, postoperative complications (within 30 days of surgery), ostomy-related complications, and survival.
  
  
  RESULTS
  19 stomas (8 ileostomies and 11 colostomies) were created in 18 patients. Six children had immunodeficiency disorders; 12 were immunosuppressed from chemotherapy treatment for cancer. Indications for surgery included infectious complications (n = 8); neoplasm-induced bowel obstruction, perforation, or invasion (n = 10); and Hirschsprung's disease (n = 1). Postoperative complications occurred in 13 cases (68%); two warranted reoperation. Four of six patients with neutropenia had serious postoperative infectious complications. Stoma complications occurred in 6 cases (32%); 1 required revision. All 3 patients in whom bleeding developed from their stoma site were thrombocytopenic. Nine of 18 patients (50%) died, yet no patient died of complications attributable to their stomas. Of the surviving 9 children, 6 underwent stoma takedown at a mean of 19 months after creation; 1 has a permanent colostomy, and 2 currently are undergoing chemotherapy.
  
  
  CONCLUSIONS
  Although immunocompromised children who require intestinal stomas frequently die of their underlying illnesses and their stomas often produce considerable morbidity, stoma creation does not jeopardize their chance of survival.
authors.affiliation: Division of Pediatric Surgery, Childrens Hospital Los Angeles and the University of Southern California School of Medicine, 90027, USA.
authors.forename: S
authors.initials: S
authors.lastname: Rokhsar
authors.forename: E A
authors.initials: EA
authors.lastname: Harrison
authors.forename: D B
authors.initials: DB
authors.lastname: Shaul
authors.forename: J D
authors.initials: JD
authors.lastname: Phillips
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003125:Colostomy; D005260:Female; D006801:Humans; D007081:Ileostomy; D016867:Immunocompromised Host; D007231:Infant, Newborn; D008297:Male; D011183:Postoperative Complications; D012189:Retrospective Studies