title: Removal of silicone oil with vision improvement after rhegmatogenous retinal detachment following CMV retinitis in patients with AIDS.
abstract: OBJECTIVE
  To report that silicone oil may be safely removed from immuno-recovered patients with acquired immunodeficiency syndrome (AIDS) after instillation for cytomegalovirus (CMV)-related rhegmatogenous retinal detachment.
  
  
  METHODS
  We report two patients with CMV-related retinal detachment who had previously been treated with vitrectomy and silicone oil.
  
  
  RESULTS
  Six months after removal of silicone oil, the retina remained attached in both patients. Without specific anti-CMV therapy, there was no relapse of CMV retinitis while patients were undergoing highly active antiretroviral therapy. Best-corrected visual acuity improved in both patients.
  
  
  CONCLUSIONS
  It appears to be possible to remove silicone oil safely from patients with AIDS who show immune recovery, thus avoiding side effects of long-standing silicone oil and increasing quality of life. After silicone oil removal, visual acuity was improved.
authors.affiliation: University Eye Hospital, Munich, Germany.
authors.forename: U C
authors.initials: UC
authors.lastname: Schaller
authors.forename: J C
authors.initials: JC
authors.lastname: MacDonald
authors.forename: A J
authors.initials: AJ
authors.lastname: Mueller
authors.forename: M P
authors.initials: MP
authors.lastname: Karavellas
authors.forename: V
authors.initials: V
authors.lastname: Klauss
authors.forename: A
authors.initials: A
authors.lastname: Scheider
authors.forename: A
authors.initials: A
authors.lastname: Kampik
authors.forename: W R
authors.initials: WR
authors.lastname: Freeman
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D017726:Cytomegalovirus Retinitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006678:HIV / Q000276:immunology; D015483:HIV Antibodies / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012008:Recurrence; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D012827:Silicone Oils; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods
chemical_list: D019380:Anti-HIV Agents; D015483:HIV Antibodies; D012827:Silicone Oils