title: Rationality of drug prescriptions in rural health centres in Burkina Faso.
abstract: The objective of this study is to investigate the quality of drug prescriptions in nine health centres of three districts in rural Burkina Faso. 313 outpatient consultations were studied by methods of guided observation. Additionally interviews were held with the health care workers involved in the study. A total of 793 drugs prescribed by 15 health care workers during the observation period and 2815 prescribed drugs copied from the patient register were analyzed. An average of 2.3 drugs were prescribed per visit. 88.0% of the prescribed drugs were on the essential drug list. 88.4% were indicated according to the national treatment guidelines. 79.4% had a correct dosage. The study revealed serious deficiencies in drug prescribing that could not be detected by assessing selected quantitative drug-use indicators as recommended by the WHO. In two-thirds of the cases the patients received no information on how long the drug had to be taken. Errors in dosage occurred significantly more often in children under 5 years. The combined analysis of choice and dosage of drugs showed that 59.3% of all the patients received a correct prescription. Seven out of 21 pregnant women received drugs contraindicated in pregnancy. We conclude that assessment of quantitative drug-use indicators alone does not suffice in identifying specific needs for improvement in treatment quality. We recommend that prescribing for children under 5 and for pregnant women should be targeted in future interventions and that the lay-out, content and distribution of treatment guidelines must be improved.
authors.affiliation: Institute for Tropical Hygiene and Public Health (ITHOG), University of Heidelberg, Germany. gck8a@ibm.net
authors.forename: G
authors.initials: G
authors.lastname: Krause
authors.forename: M
authors.initials: M
authors.lastname: Borchert
authors.forename: J
authors.initials: J
authors.lastname: Benzler
authors.forename: R
authors.initials: R
authors.lastname: Heinmüller
authors.forename: I
authors.initials: I
authors.lastname: Kaba
authors.forename: M
authors.initials: M
authors.lastname: Savadogo
authors.forename: N
authors.initials: N
authors.lastname: Siho
authors.forename: H J
authors.initials: HJ
authors.lastname: Diesfeld
mesh_terms: D001291:Attitude of Health Personnel; D002050:Burkina Faso; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D004363:Drug Utilization / Q000592:standards*; D005069:Evaluation Studies as Topic; D005260:Female; D006302:Health Services Research; D006801:Humans; D010349:Patient Compliance; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011787:Quality of Health Care; D019035:Rural Health Services / Q000458:organization & administration* / Q000592:standards