Multiple functions of polypeptides mediated by distinct domains interacting with different receptors.
There exist multiple functions of polypeptide molecules. Both a polypeptide molecule interacting with one receptor, and distinct domains of the molecule interacting with different receptors could induce different intracellular signal transduction to elicit multiple functions. This review highlights the distinct domains of the polypeptide molecule interacting with different receptors to elicit multiple functions. It includes distinct domains, different receptor mechanisms, and different signal transduction of the polypeptide molecule.
Jiang
C L
CL
Department of Neurobiology, Second Military Medical University, Shanghai, P.R. China. jiangclk@online.sh.cn
Lu
C L
CL
Chen
Y Z
YZ
Liu
X Y
XY
D000818:Animals; D006801:Humans; D007376:Interleukin-2 / Q000737:chemistry / Q000378:metabolism*; D015375:Receptors, Interleukin-2 / Q000378:metabolism*; D015398:Signal Transduction
D007376:Interleukin-2; D015375:Receptors, Interleukin-2