title: Predominance of the T14484C mutation in French-Canadian families with Leber hereditary optic neuropathy is due to a founder effect.
authors.forename: C
authors.initials: C
authors.lastname: Macmillan
authors.forename: T A
authors.initials: TA
authors.lastname: Johns
authors.forename: K
authors.initials: K
authors.lastname: Fu
authors.forename: E A
authors.initials: EA
authors.lastname: Shoubridge
mesh_terms: D002170:Canada / Q000453:epidemiology; D004252:DNA Mutational Analysis; D004272:DNA, Mitochondrial / Q000032:analysis / Q000235:genetics*; D005260:Female; D018703:Founder Effect; D005602:France / Q000208:ethnology; D006801:Humans; D008297:Male; D015418:Optic Atrophies, Hereditary / Q000208:ethnology* / Q000235:genetics; D010375:Pedigree; D017354:Point Mutation
chemical_list: D004272:DNA, Mitochondrial