The HIV protease inhibitors saquinavir, ritonavir, and nelfinavir but not indinavir impair the epithelial barrier in the human intestinal cell line HT-29/B6.
Bode
H
H
Schmidt
W
W
Schulzke
J D
JD
Fromm
M
M
Zippel
T
T
Wahnschaffe
U
U
Bendfeldt
K
K
Riecken
E O
EO
Ullrich
R
R
D017320:HIV Protease Inhibitors / Q000493:pharmacokinetics / Q000633:toxicity*; D019073:HT29 Cells; D006801:Humans; D019469:Indinavir / Q000493:pharmacokinetics / Q000633:toxicity; D007413:Intestinal Mucosa / Q000166:cytology / Q000378:metabolism*; D017136:Ion Transport; D019888:Nelfinavir / Q000493:pharmacokinetics / Q000633:toxicity; D019438:Ritonavir / Q000493:pharmacokinetics / Q000633:toxicity; D019258:Saquinavir / Q000493:pharmacokinetics / Q000633:toxicity
D017320:HIV Protease Inhibitors; D019469:Indinavir; D019888:Nelfinavir; D019258:Saquinavir; D019438:Ritonavir