[Time course of ventilatory drive in patients with kyphoscoliosis before and during intermittent ventilation].
The aim of this retrospective study was to investigate the mouth-occlusion-pressure under CO2-stimulation in five patients (3 women, 2 men) suffering from kyphoscoliosis of different aetiology whilst being under noninvasive ventilation for respiratory muscle fatigue. Ten months after initiation of noninvasive ventilation we could demonstrate a marginal improvement of respiratory muscle strength but the P0.1 CO2-decreased slightly. We conclude that this decrease might be due to an increase in tidal volume allowing for a reduction in respiratory rate.
Feldmeyer
F
F
Abteilung für Pneumologie, Allergologie und Schlafmedizin, Klinik Ambrock, Hagen.
Randerath
W
W
Rühle
K H
KH
D005260:Female; D005500:Follow-Up Studies; D005621:Friedreich Ataxia / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D007384:Intermittent Positive-Pressure Breathing; D008297:Male; D008875:Middle Aged; D018763:Muscle Fatigue; D012132:Respiratory Muscles / Q000503:physiopathology; D014797:Vital Capacity