Ergotism related to a single dose of ergotamine tartrate in an AIDS patient treated with ritonavir.
We report a rare case of ergotism related to a single dose of ergotamine tartrate in a man with AIDS being treated with ritonavir. He was treated with a prostacyclin analogue and made a complete recovery.
Blanche
P
P
Service de Médecine Interne 2, Hôpital Cochin, Université René Descartes, Paris, France.
Rigolet
A
A
Gombert
B
B
Ginsburg
C
C
Salmon
D
D
Sicard
D
D
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D000328:Adult; D000075202:Contraindications; D051544:Cytochrome P-450 CYP3A; D065607:Cytochrome P-450 Enzyme Inhibitors; D004334:Drug Administration Schedule; D004878:Ergotamine / Q000506:poisoning*; D004881:Ergotism / Q000209:etiology*; D017320:HIV Protease Inhibitors / Q000627:therapeutic use; D006801:Humans; D008297:Male; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors; D019438:Ritonavir / Q000627:therapeutic use; D014662:Vasoconstrictor Agents / Q000506:poisoning*
D065607:Cytochrome P-450 Enzyme Inhibitors; D017320:HIV Protease Inhibitors; D014662:Vasoconstrictor Agents; D006899:Mixed Function Oxygenases; C104464:CYP3A protein, human; D051544:Cytochrome P-450 CYP3A; D019438:Ritonavir; D004878:Ergotamine