Deletion (1)(q12) and double minutes in a metastatic adenocarcinoma of the prostate.
Cytogenetic analysis after short-term cultures were performed on an invasive and moderately-differentiated prostatic adenocarcinoma. The results showed a normal male chromosomal complement in most metaphases examined. Furthermore, several abnormalities were found, including del(1)(q12), double minute and ring chromosomes, acentric fragments, triradial figures, and near-tetraploid cells.
Carvalho-Salles
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AB
Departmento de Biologia, Instituto de Biociências, Letras e Ciências Exatas, São José do Rio Preto, Brazil.
Mesquita
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JC
Tajara
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EH
D000230:Adenocarcinoma / Q000235:genetics*; D000368:Aged; D002878:Chromosomes, Human, Pair 1; D017353:Gene Deletion; D006801:Humans; D007621:Karyotyping; D008297:Male; D009362:Neoplasm Metastasis; D011003:Ploidies; D011471:Prostatic Neoplasms / Q000235:genetics*; D012303:Ring Chromosomes; D014407:Tumor Cells, Cultured