title: Carboprost exposure in a newborn with recovery.
abstract: BACKGROUND
  This case describes a newborn who was accidentally given carboprost (Hemabate) 250 micrograms intramuscularly, the largest amount ever reported in a normal newborn.
  
  
  METHODS
  A full-term newborn was inadvertently given carboprost rather than his prescribed hepatitis vaccine. Within 15 minutes, he was tachypneic and hypertensive followed by bronchospasms and dystonic movements and/or seizure activity of his upper extremities. He also was hyperthermic and had diarrhea stools. He recovered within 18 hours and was discharged.
  
  
  CONCLUSIONS
  The manufacturer reports 2 infants who received lesser amounts and remained asymptomatic. This child exhibited symptoms associated with an overdose of a prostaglandin F2a, although complete recovery occurred within 18 hours.
authors.affiliation: Pittsburgh Poison Center, Pennyslvania, USA. Mrvosr@chplink.chp.edu
authors.forename: R
authors.initials: R
authors.lastname: Mrvos
authors.forename: F J
authors.initials: FJ
authors.lastname: Kerr
authors.forename: E P
authors.initials: EP
authors.lastname: Krenzelok
mesh_terms: D002260:Carboprost / Q000008:administration & dosage / Q000506:poisoning*; D005334:Fever / Q000139:chemically induced; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D007231:Infant, Newborn; D007273:Injections, Intramuscular; D008297:Male; D008508:Medication Errors; D010120:Oxytocics / Q000008:administration & dosage / Q000506:poisoning*
chemical_list: D010120:Oxytocics; D002260:Carboprost