Cinnamon extracts' inhibitory effect on Helicobacter pylori.
Ethanol and methylene chloride extracts of cinnamon were compared for their effect on Helicobacter pylori growth and urease activity. Methylene chloride extract was found to inhibit growth of H. pylori, while ethanol extract counteracted its urease activity. Cinnamon extract (from methylene chloride) inhibited H. pylori at concentration range of common antibiotics. Complete inhibition in vitro was achieved by 50 microg/ml in solid medium (egg yolk emulsion agar) and by 15 microg/ml in liquid medium (supplemented brain heart infusion broth). The cinnamon extracts were more inhibitory on free urease than on whole cell urease.
Tabak
M
M
Food Engineering and Biotechnology Faculty, Technion, Haifa, Israel.
Armon
R
R
Neeman
I
I
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002935:Cinnamomum zeylanicum; D016480:Helicobacter pylori / Q000187:drug effects* / Q000254:growth & development; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D010936:Plant Extracts