title: Wolman's disease diagnosed by intestinal biopsy.
abstract: We describe a fatal case of Wolman's disease in a 5-month-old Italian infant with severe gastrointestinal symptoms in whom the diagnosis was made from intestinal biopsy findings at the age of 3 1/2 months. Abdominal CT scan, elevated blood acid phosphatase levels and histologic findings confirmed the diagnosis.
authors.affiliation: Department of Gastroenterology, Children's Hospital Bambino Gesù, Rome, Italy. castro@obg-irccs.rm.it
authors.forename: M
authors.initials: M
authors.lastname: Castro
authors.forename: P
authors.initials: P
authors.lastname: Rosati
authors.forename: R
authors.initials: R
authors.lastname: Boldrini
authors.forename: V
authors.initials: V
authors.lastname: Lucidi
authors.forename: M
authors.initials: M
authors.lastname: Gambarara
authors.forename: C
authors.initials: C
authors.lastname: Bosman
mesh_terms: D001707:Biopsy, Needle; D018450:Disease Progression; D016145:Endoscopy, Digestive System; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D007413:Intestinal Mucosa / Q000473:pathology*; D008297:Male; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D015223:Wolman Disease / Q000175:diagnosis / Q000473:pathology*