Re-irradiation for recurrent rhabdomyosarcoma of the nasopharynx in a child.
There are few clinical situations where high dose re-irradiation with curative intent is indicated in children. Because of the potential for serious late sequelae, re-irradiation is considered only in the unusual situation where there is just local recurrence and surgery and/or chemotherapy are unlikely to provide long-term control. The authors present a case of nasopharynx rhabdomyosarcoma in a child which recurred after high dose irradiation and chemotherapy and was then re-irradiated to a high dose. The child is well without any serious sequelae more than 13 years following completion of the second course of radiotherapy.
Deutsch
M
M
University of Pittsburgh Medical Center, Department of Radiation Oncology, PA 15213, USA.
Orlando
S J
SJ
D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000532:radiotherapy*; D012208:Rhabdomyosarcoma / Q000188:drug therapy / Q000532:radiotherapy*
D000970:Antineoplastic Agents