title: [Combined sclerosis of the spinal cord "revisited"].
abstract: RENEWED INTEREST: There are at least three reasons for revisiting subacute combined degeneration.
  
  
  METHODS
  There is evidence that diagnosis is too often differed until a time when irreversible lesions of the spinal cord are present. A high degree of suspicion is mandatory.
  Magnetic resonance imaging of the spine supplies interesting information about the distribution of lesions and their course under treatment. NO: Nitous oxide is an emerging cause of cobalamin deficiency. Patients sometimes develop myeloneuropathy after repeated or single exposure to nitrous oxide. This is explained by inactivation of methylcobalamin as a result of irreversible oxidation.
authors.affiliation: Service de Neurologie, Hôpital Beaujon, Clichy.
authors.forename: C
authors.initials: C
authors.lastname: Masson
mesh_terms: D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D006801:Humans; D008279:Magnetic Resonance Imaging; D009609:Nitrous Oxide / Q000009:adverse effects*; D012307:Risk Factors; D012598:Sclerosis; D013116:Spinal Cord / Q000187:drug effects / Q000473:pathology; D013118:Spinal Cord Diseases / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D018685:Anesthetics, Inhalation; D009609:Nitrous Oxide