title: Reproducibility of home spirometry in children with newly diagnosed asthma.
abstract: We evaluated the reproducibility of home spirometry in 110 children aged 5-10 years with newly diagnosed asthma according to the criteria proposed by the American Thoracic Society (level of reproducibility < or = 5%). Flow-volume spirometry was performed in the clinic. Spirometric values were then monitored twice daily at home for 24 days (mean), using a novel device, the Vitalograph(R) Data Storage Spirometer (Vitalograph, Ltd., Buckingham, UK). During this period, the mean (SD) compliance in performing the spirometric tests was 94% (7). In the whole study population, the mean (SD) percentage of reproducible spirometric measurements was 77% (17), although there was wide individual variation (range, 21-100%). In the 5-6-year age group (n = 51), the mean (SD) percentage of reproducible spirometric values was 72.8% (18.6), in the 7-8-year group (n = 38) 77.1% (13.8), and in the 9-10-year group (n = 21) 84. 5% (13.7) analysis of variance, P = 0.02). We conclude that most of the children aged 5-10 years could perform reproducible spirometric tests during home monitoring, although there was wide individual variation. Younger children were less likely to perform reproducible tests than older children. However, a considerable proportion of the measurements (23%) did not meet the criteria of acceptable reproducibility. In order to improve the quality of home monitoring, nonreproducible measurements should be excluded from the calculations.
authors.affiliation: Department of Allergic Diseases, Helsinki University Central Hospital, Helsinki, Finland.
authors.forename: A S
authors.initials: AS
authors.lastname: Pelkonen
authors.forename: K
authors.initials: K
authors.lastname: Nikander
authors.forename: M
authors.initials: M
authors.lastname: Turpeinen
mesh_terms: D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005540:Forced Expiratory Flow Rates; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D010349:Patient Compliance; D015203:Reproducibility of Results; D012648:Self Care / Q000592:standards*; D013147:Spirometry / Q000592:standards*; D014797:Vital Capacity
chemical_list: D018927:Anti-Asthmatic Agents