title: Binding of small phosphorylated chromatin peptides to DNA.
abstract: Low-molecular-weight peptides involved in gene expression and cell growth have been isolated from DNA preparation from eukaryotic cells. After phosphorylation with protein kinase CKII (pCKII) these peptides are able to bind to DNA in presence of divalent cations and salt/ethanol. This finding may explain the mechanism by which the peptides exert their activity.
authors.affiliation: Dipartimento di Biologia Cellulare e Molecolare, Sez. di Fisiologia e Biofisica, Università di Perugia, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Cardellini
authors.forename: F
authors.initials: F
authors.lastname: Adami
authors.forename: G L
authors.initials: GL
authors.lastname: Gianfranceschi
mesh_terms: D000818:Animals; D047390:Casein Kinase II; D002843:Chromatin / Q000737:chemistry* / Q000378:metabolism; D004247:DNA / Q000378:metabolism*; D005057:Eukaryotic Cells; D010748:Phosphopeptides / Q000378:metabolism*; D010766:Phosphorylation; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism
chemical_list: D002843:Chromatin; D010748:Phosphopeptides; D004247:DNA; D047390:Casein Kinase II; D017346:Protein Serine-Threonine Kinases