[Immune sensor for determining myoglobin level].
For the first time, the photoluminescence of porous silicon was used to create an immune sensor capable of detection of low concentrations of myoglobin important for the diagnostics of heart failure diseases which in both model solutions and human serum, being. It is shown that the sensitivity of the sensor was 10 ng/ml, time of 1 measurement--15-30 min. Duration of the analysis can be even shorter if measurements are performed in the kinetic regime. The comparison of the characteristics of the immune sensor and standard method ELISA is also given in the paper.
Starodub
V M
VM
A.V. Palladin Institute of Biochemistry of National Academy of Sci.
Fedorenko
L L
LL
Sisets'kyĭ
A P
AP
Kurs'kyĭ
M D
MD
D015374:Biosensing Techniques; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007700:Kinetics; D049449:Luminescence; D009211:Myoglobin / Q000032:analysis*; D012680:Sensitivity and Specificity
D009211:Myoglobin