title: [Consensus on the diagnosis of multi-system atrophy].
abstract: We report the results of a consensus conference on the diagnosis of multiple system atrophy. We describe the clinical features of the disease, which include four domains: autonomic failure/urinary dysfunction, parkinsonism and cerebellar ataxia, and corticospinal dysfunction. We set criteria to define the relative importance of these features. The diagnosis of possible multiple system atrophy requires one criterion plus two features from separate domains. The diagnosis of probable multiple system atrophy requires the criterion for autonomic failure/urinary dysfunction plus poor levodopa responsive parkinsonism or cerebellar ataxia. The diagnosis of definite multiple system atrophy requires pathological confirmation.
authors.affiliation: Department of Neurology, University of Michigan Medical Center, Ann Arbor, USA.
authors.forename: S
authors.initials: S
authors.lastname: Gilman
authors.forename: P
authors.initials: P
authors.lastname: Low
authors.forename: N
authors.initials: N
authors.lastname: Quinn
authors.forename: A
authors.initials: A
authors.lastname: Albanese
authors.forename: Y
authors.initials: Y
authors.lastname: Ben-Shlomo
authors.forename: C
authors.initials: C
authors.lastname: Fowler
authors.forename: H
authors.initials: H
authors.lastname: Kaufmann
authors.forename: T
authors.initials: T
authors.lastname: Klockgether
authors.forename: A
authors.initials: A
authors.lastname: Lang
authors.forename: P
authors.initials: P
authors.lastname: Lantos
authors.forename: I
authors.initials: I
authors.lastname: Litvan
authors.forename: C
authors.initials: C
authors.lastname: Mathias
authors.forename: E
authors.initials: E
authors.lastname: Oliver
authors.forename: D
authors.initials: D
authors.lastname: Robertson
authors.forename: I
authors.initials: I
authors.lastname: Schatz
authors.forename: G
authors.initials: G
authors.lastname: Wenning
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D019578:Multiple System Atrophy / Q000175:diagnosis*