title: Idiopathic dilated cardiomyopathy presenting in pregnancy.
abstract: OBJECTIVE
  To describe the clinical course and management of a patient who presented with idiopathic dilated cardiomyopathy in early pregnancy.
  
  
  METHODS
  A 27 yr old, previously well, Chinese primigravida presented at 18 wk gestation with a history of irregular heart beat and decreased exercise tolerance. Echocardiography showed moderate left ventricular dysfunction with left ventricular ejection fraction of 35-40%. Idiopathic dilated cardiomyopathy was diagnosed. She declined termination of pregnancy and was managed medically with furosemide, digoxin and potassium supplements. Low molecular weight heparin was prescribed. Emergency Cesarean delivery was performed at 31 wk gestation because of deteriorating liver function and a non-reassuring fetal heart rate pattern. General anesthesia was given because of relative urgency, the patient's wish, and concerns about potential risk of spinal hematoma. Invasive monitoring with pulmonary and radial artery catheters was used and low dose inotropic support was given. Postoperatively, she was managed in the intensive care and coronary care units where she was treated with dobutamine, furosemide, digoxin, potassium, captopril, losartin and warfarin. Her postoperative course was complicated by a severe embolic stroke five weeks after delivery and she died five months later.
  
  
  CONCLUSIONS
  Idiopathic dilated cardiomyopathy may rarely present in pregnancy. A multidisciplinary approach and close peripartum monitoring are important in management and termination of pregnancy should be considered. Thromboembolic complications are a major risk.
authors.affiliation: Department of Anaesthesia & Intensive Care, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, China.
authors.forename: F
authors.initials: F
authors.lastname: Chan
authors.forename: W D
authors.initials: WD
authors.lastname: Ngan Kee
mesh_terms: D000328:Adult; D000773:Anesthesia, Obstetrical; D002311:Cardiomyopathy, Dilated / Q000503:physiopathology / Q000628:therapy*; D002585:Cesarean Section; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology / Q000628:therapy*