title: Molecular epidemiology of Fonsecaea pedrosoi using mitochondrial DNA analysis.
abstract: Restriction fragment length polymorphism (RFLP) of mitochondrial DNA (mtDNA) from 49 clinical Fonsecaea pedrosoi isolates (18 isolates from Japan, 17 from Madagascar, 7 from Argentina, 5 from Venezuela, 1 from Costa Rica and 1 unknown) was studied. The 49 isolates were composed of 20 isolates of Type 1, 16 of Type 2, 12 of Type 4 and 1 of a new mtDNA type, Type 7, which was closely related to Type 2. On the bases of the results of 120 isolates of the present (49 isolates) and previous (71 isolates) studies, F. pedrosoi was classified into seven mtDNA types and according to the relationship between mtDNA types and geographic origins: in Japan and probably in China, Type 1 isolates; in Zaire and Madagascar, Type 2; in Central and South America, Type 4 and Type 1. These results indicated that the geographical origin of F. pedrosoi isolate could be roughly inferred from its mtDNA type.
authors.affiliation: Department of Dermatology, Kanazawa Medical University, Ishikawa, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kawasaki
authors.forename: M
authors.initials: M
authors.lastname: Aoki
authors.forename: H
authors.initials: H
authors.lastname: Ishizaki
authors.forename: M
authors.initials: M
authors.lastname: Miyaji
authors.forename: K
authors.initials: K
authors.lastname: Nishimura
authors.forename: K
authors.initials: K
authors.lastname: Nishimoto
authors.forename: T
authors.initials: T
authors.lastname: Matsumoto
authors.forename: C
authors.initials: C
authors.lastname: De Vroey
authors.forename: R
authors.initials: R
authors.lastname: Negroni
authors.forename: M
authors.initials: M
authors.lastname: Mendonca
authors.forename: A
authors.initials: A
authors.lastname: Andriantsimahavandy
authors.forename: P
authors.initials: P
authors.lastname: Esterre
mesh_terms: D002862:Chromoblastomycosis / Q000382:microbiology*; D004272:DNA, Mitochondrial / Q000145:classification*; D006801:Humans; D003904:Mitosporic Fungi / Q000235:genetics*; D010802:Phylogeny; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D004272:DNA, Mitochondrial