title: Nevoid hyperkeratosis of the nipple and areola: treatment with topical retinoic acid.
abstract: Nevoid hyperkeratosis of the nipple and areola is a rare dermatosis with unknown etiology, (Perez-Izquierdo JM, Vilata JJ, Sanchez JL, et al. Retinoic acid treatment of nipple hyperkeratosis. Arch Dermatol 1990;126:687-688). Only 40 cases have been reported until 1997 (Alpsoy E, Yilmaz E, Aykol A. Hyperkeratosis of the nipple: report of two cases. J Dermatol 1997;24:43-45). The disease has a benign course and may only be a cosmetic problem. Different modalities have been used in the treatment of NHNA. In our case treatment with topical retinoic acid induced an acceptable response.
authors.affiliation: Department of Dermatology, Istanbul Medical Faculty, Istanbul University, Turkey.
authors.forename: G
authors.initials: G
authors.lastname: Okan
authors.forename: C
authors.initials: C
authors.lastname: Baykal
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D001941:Breast Diseases / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000473:pathology; D007633:Keratins; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D007642:Keratosis / Q000188:drug therapy* / Q000473:pathology; D009558:Nipples / Q000473:pathology*; D014212:Tretinoin / Q000008:administration & dosage / Q000627:therapeutic use*; D014860:Warts / Q000473:pathology
chemical_list: D007641:Keratolytic Agents; D014212:Tretinoin; D007633:Keratins