Rare polymorphisms in the promoter regions of the human interleukin-12 p35 and interleukin-12 p40 subunit genes.
We have described two rare, single-nucleotide polymorphisms within the promoter regions of the IL-12 p35 and p40 subunit genes. Transitions C to T at position -916 from the transcription start of the IL-12 p35 gene and G to T at position -1287 in the IL-12 p40 gene were observed.
Pravica
V
V
Immunology Research Group, School of Biological Sciences, University of Manchester, UK.
Brogan
I J
IJ
Hutchinson
I V
IV
D001483:Base Sequence; D017124:Conserved Sequence; D014644:Genetic Variation; D006801:Humans; D018664:Interleukin-12 / Q000235:genetics*; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D018807:Polymorphism, Single-Stranded Conformational; D011401:Promoter Regions, Genetic
D018664:Interleukin-12