title: Fatal cerebral hemorrhage and severe thrombocytopenia during abciximab treatment.
abstract: We describe the case of a fatal cerebral hemorrhage associated with a severe thrombocytopenia (4.0 x 10(9)/l), occurring only 90 min after starting treatment with abciximab, in a patient undergoing primary percutaneous transluminal coronary angioplasty (PTCA) for an acute myocardial infarction. Cathet. Cardiovasc. Intervent. 49:177-180, 2000.
authors.affiliation: Department A of Cardiology, La Timone Hospital, University of Marseille, France.
authors.forename: B
authors.initials: B
authors.lastname: Vahdat
authors.forename: I
authors.initials: I
authors.lastname: Canavy
authors.forename: L
authors.initials: L
authors.lastname: Fourcade
authors.forename: E
authors.initials: E
authors.lastname: Garcia
authors.forename: J
authors.initials: J
authors.lastname: Quilici
authors.forename: J L
authors.initials: JL
authors.lastname: Bonnet
authors.forename: M
authors.initials: M
authors.lastname: Bory
mesh_terms: D000077284:Abciximab; D015906:Angioplasty, Balloon, Coronary; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D002543:Cerebral Hemorrhage / Q000139:chemically induced* / Q000000981:diagnostic imaging; D017023:Coronary Angiography; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000009:adverse effects*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000628:therapy; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors*; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000150:complications; D013927:Thrombosis / Q000517:prevention & control; D014057:Tomography, X-Ray Computed
chemical_list: D000911:Antibodies, Monoclonal; D007140:Immunoglobulin Fab Fragments; D010975:Platelet Aggregation Inhibitors; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D000077284:Abciximab