Fibromuscular dysplasia.
Fibromuscular dysplasia is an uncommon angiopathy that occurs in young to middle-aged, predominately female individuals. The disease consists of a heterogeneous group of histologic changes, which ultimately lead to arterial narrowing. Clinical manifestations reflect the arterial bed involved, most commonly hypertension (renal) and stroke (carotid). Fibromuscular dysplasia is a pathologic diagnosis, but the characteristic changes seen on an angiogram can be used to make the diagnosis in the appropriate clinical setting. This noninflammatory disease is a common mimic of vasculitis. A very limited amount of new literature has been published in the past year about this relatively uncommon condition.
Begelman
S M
SM
Department of Vascular Medicine, Cleveland Clinic Foundation, OH, USA.
Olin
J W
JW
D002493:Central Nervous System Diseases / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D005352:Fibromuscular Dysplasia / Q000150:complications / Q000209:etiology / Q000473:pathology; D006801:Humans; D006978:Hypertension, Renovascular / Q000209:etiology; D008297:Male