[The effect of hypokinesia on the development of allergic reactions in an experiment].
434 mature and immature guinea pigs were divided into two groups. Test animals were kept under hypokinesia for 72 days. Control animals were not exposed to hypokinesia. Sensitization was made on day 60 in both the groups. On sensitization day 10, blood count was made, on day 12 anaphylactic shock was induced in all the animals. Allergological and immunological tests have shown that hypokinesia contributes to development of immediate allergy in animals of different age and therefore can be considered as a risk factor of allergy of immediate type.
Galiev
R S
RS
D000707:Anaphylaxis / Q000209:etiology / Q000276:immunology / Q000503:physiopathology; D000818:Animals; D000917:Antibody Formation; D006168:Guinea Pigs; D006969:Hypersensitivity, Immediate / Q000209:etiology* / Q000276:immunology / Q000503:physiopathology; D018476:Hypokinesia / Q000150:complications* / Q000276:immunology / Q000503:physiopathology; D007111:Immunity, Cellular; D007114:Immunization; D012741:Sexual Maturation / Q000276:immunology; D013997:Time Factors