Electroretinographic characteristics of proliferative vitreoretinopathy in rhegmatogenous detachment of retina.
Thirty-five patients with types A, B, C2, C3, and D1 proliferative vitreoretinopathy (PVR) were followed up for 8-14 months after surgical treatment of rhegmatogenic amotio retinae. Hanz-Feld electroretinogram (ERG), rhythmic ERG to low and high-frequency stimulation, and macular ERG were recorded. Before surgery all patients presented with specific signs of changes in the retinal electrogenesis, characteristic of rhegmatogenic amotio retinae with PVR of different types. Comparative analysis of ERG and rhythmic ERG alteration showed a more expressed reaction of Mueller's glial cells in patients with types A-C2 PVR and of second order neurons in the internal nuclear layer of the retina in those with types C3 and D1 PVR. Characteristic changes in the retinal functional activity were detected, possessing a prognostic significance. According to electrophysiological studies, the decisive factor for predicting the course of recovery after surgical treatment of retinal detachment is the preoperative function of retinal neurons. A drastic depression of low-frequency rhythmic ERG is the most unfavorable sign in prognosis of the postoperative time course of visual functions. The least favorable course of recovery after the operation is typical of amotio retinae with type C3 PVR. Recovery of amplitudes of different biopotentials and functional horizontal bonds at different levels of the retinal structure is different.
Antelava
N D
ND
Zueva
M V
MV
Tsapenko
I V
IV
Zakharova
G Iu
GIu
D004596:Electroretinography; D006801:Humans; D008266:Macula Lutea / Q000503:physiopathology*; D011237:Predictive Value of Tests; D012163:Retinal Detachment / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery; D018630:Vitreoretinopathy, Proliferative / Q000150:complications / Q000503:physiopathology*