title: Association of systemic lupus erythematosus and hemolytic uremic syndrome in a child.
abstract: We describe a 10-year-old girl with systemic lupus erythematosus (SLE) who first presented with hemolytic uremic syndrome (HUS). Diagnoses were based on the classic HUS triad, including the observation of fragmented red blood cells, and on the American College of Rheumatology criteria for SLE. Plasma exchange may have been effective against both HUS and SLE in this patient, as it was associated with improvement of platelet counts, renal function, and serological findings.
authors.affiliation: Department of Pediatrics, Gunma University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ogawa
authors.forename: H
authors.initials: H
authors.lastname: Arai
authors.forename: K
authors.initials: K
authors.lastname: Maruyama
authors.forename: T
authors.initials: T
authors.lastname: Watanabe
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: O
authors.initials: O
authors.lastname: Kikuchi
authors.forename: A
authors.initials: A
authors.lastname: Morikawa
mesh_terms: D002648:Child; D005260:Female; D019085:Fluorescent Antibody Technique, Direct; D005920:Glomerular Mesangium / Q000473:pathology; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D007668:Kidney / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008854:Microscopy, Electron; D010951:Plasma Exchange
chemical_list: D007074:Immunoglobulin G