title: Apatite formation on organic monolayers in simulated body environment.
abstract: Organic monolayer films with the same functional groups as collagen were prepared by a Langmuir-Blodgett (LB) method and the LB monolayers were soaked in a simulated body fluid. Nucleation of hydroxyapatite (HA) took place on the monolayers of the carboxyl group, while no nucleation occurred on the monolayers of amino groups. From IR spectra analyses it was found that an interfacial interaction between carboxyl groups and Ca ions was important for the HA nucleation, causing the formation of HA crystals from the simulated body environment.
authors.affiliation: National Institute for Research in Inorganic Materials, Namiki 1-1, Tsukuba, Ibaraki 305-0044, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sato
authors.forename: Y
authors.initials: Y
authors.lastname: Kumagai
authors.forename: J
authors.initials: J
authors.lastname: Tanaka
mesh_terms: D000588:Amines; D001031:Apatites; D001826:Body Fluids; D018786:Bone Substitutes; D003094:Collagen; D003460:Crystallization; D004537:Eicosanoic Acids; D007477:Ions; D008954:Models, Biological; D009994:Osmolar Concentration
chemical_list: D000588:Amines; D001031:Apatites; D018786:Bone Substitutes; D004537:Eicosanoic Acids; D007477:Ions; D003094:Collagen; C009317:stearylamine; C094477:arachidic acid