title: Fracture healing of the sheep tibia treated using a unilateral external fixator. Comparison of static and dynamic fixation.
abstract: It is generally accepted that when a fracture is treated with external fixation, dynamization of the fixation accelerates formation of the bony callus by transferring part of the functional loads. The aim of the research presented here was to validate this principle using in vivo measurements of callus stiffness. We created a transverse fracture in the mid third of the tibial shaft in 12 sheep and maintained a 3 mm gap between the fragments for 3 weeks. Two types of unilateral external fixators were applied. Axial loading was permitted (dynamization) from the fourth week onwards in 6 animals. In the other 6 animals, fixation remained static for both types of fixation. Weekly measurements of callus stiffness were obtained using a goniometer and load cell to assess bending stiffness. Two slightly different fixators were used. Callus formed in all 12 animals. Callus stiffness increased exponentially to reach the degree of stiffness measured on the contralateral side. There was no clear difference in healing between the two types of fixations nor between dynamic and static fixation. If a unilateral fixator was applied which did not maintain absolutely rigid fixation, the fracture generally healed well even without contact between the fragment ends. If the process of callus formation had begun normally, dynamic fixation offered no further benefit. Measuring the stiffness of the callus with an adequate measurement apparatus in vivo indicated that the fixator could be removed earlier than would have been authorized on the basis of radiological evidence alone.
authors.affiliation: Trauma Department of Surgery, University of Regensburg, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Hente
authors.forename: J
authors.initials: J
authors.lastname: Cordey
authors.forename: B A
authors.initials: BA
authors.lastname: Rahn
authors.forename: M
authors.initials: M
authors.lastname: Maghsudi
authors.forename: S
authors.initials: S
authors.lastname: von Gumppenberg
authors.forename: S M
authors.initials: SM
authors.lastname: Perren
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D016267:External Fixators; D005260:Female; D005592:Fracture Fixation / Q000295:instrumentation / Q000379:methods*; D017102:Fracture Healing / Q000502:physiology*; D012756:Sheep; D013977:Tibia / Q000503:physiopathology / Q000601:surgery*; D013978:Tibial Fractures / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome