Preretinal haemorrhages: an unusual manifestation of intravitreal amikacin toxicity.
OBJECTIVE
To report a case with multiple preretinal haemorrhages after intravitreal amikacin.


METHODS
A 58-year-old patient developed postoperative endophthalmitis following a routine extracapsular cataract extraction in his left eye. He received two intravitreal injections of cephazoline (2.25 mg) and amikacin (0.4 mg), given 48 h apart.


RESULTS
The patient presented to us with large preretinal haemorrhages at the posterior pole. Multiple large areas of blocked fluorescence were seen on fundus fluorescein angiography.


CONCLUSIONS
Widespread posterior pole preretinal haemorrhages may be an unusual manifestation of intravitreal amikacin toxicity.
Kumar
A
A
Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institutes of Medical Sciences, New Delhi.
Dada
T
T
D000583:Amikacin / Q000009:adverse effects*; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002387:Cataract Extraction / Q000009:adverse effects; D009877:Endophthalmitis / Q000188:drug therapy / Q000209:etiology; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D012166:Retinal Hemorrhage / Q000139:chemically induced* / Q000175:diagnosis; D014792:Visual Acuity; D014822:Vitreous Body
D000900:Anti-Bacterial Agents; D000583:Amikacin