title: Dentin desensitizing effects of Gluma Alternate, Health-Dent Desensitizer and Scotchbond Multi-Purpose.
abstract: OBJECTIVE
  To evaluate the effects of topical applications of Gluma Alternate, a Gluma Desensitizer version with reduced glutaraldehyde content, Health-Dent Desensitizer and Scotchbond Multi-Purpose (SMP) on hypersensitive erosion/abrasion lesions.
  
  
  METHODS
  55 patients were included in the trial with at least three teeth each presenting severe sensitivity. From a total of 184 teeth, 69 were treated with Gluma Alternate, 58 with Health Dent and 51 treated SMP, serving as a control. Sensitivity was recorded as response to cold air stimulus prior to treatment, immediately after the topical application of the agents, and after 1 week, 1 month and 6 months.
  
  
  RESULTS
  Both Gluma Alternate and SMP showed significant reduction in sensitivity between pre- and postoperative pain scores (P < 0.05). The post-treatment sensitivity scores (0 and 1) were no different between 1 week and 6 months. In the Health-Dent group only 10 of the 58 teeth showed sensitivity reduction. For this reason the remaining 48 teeth received a "rescue treatment" with Gluma Desensitizer. At the end of the 6-month observation time, all teeth treated with Gluma Alternate, Gluma Desensitizer, and SMP showed no or very little dentin sensitivity.
authors.affiliation: Dental School, University of Bologna, Italy. gdondi@alma.unibo.it
authors.forename: G
authors.initials: G
authors.lastname: Dondi dall'Orologio
authors.forename: R
authors.initials: R
authors.lastname: Lorenzi
authors.forename: M
authors.initials: M
authors.lastname: Anselmi
authors.forename: V
authors.initials: V
authors.lastname: Opisso
mesh_terms: D000328:Adult; D001548:Benzalkonium Compounds / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000188:drug therapy*; D017220:Dentin-Bonding Agents / Q000627:therapeutic use; D005260:Female; D005976:Glutaral / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008689:Methacrylates / Q000737:chemistry / Q000627:therapeutic use*; D008875:Middle Aged; D010147:Pain Measurement; D019279:Resin Cements; D016896:Treatment Outcome
chemical_list: D001548:Benzalkonium Compounds; D017220:Dentin-Bonding Agents; D008689:Methacrylates; D019279:Resin Cements; C084018:Scotchbond Multi-Purpose; C111486:gluma desensitizer; C111487:health-dent desensitizer; D005976:Glutaral