Detection of HPV-20, HPV-23, and HPV-DL332 in a solitary eyelid syringoma.
OBJECTIVE
To report evidence of many human papillomavirus types occurring in a solitary syringoma clinically appearing as a papilloma.


METHODS
A 57-year-old man presented with a 10-year history of an upper eyelid tumor. Histopathology, human papillomavirus-nested polymerase chain reaction, human papillomavirus-DNA cloning into vector pCR2.1, sequencing, and computer-assisted evaluation were performed.


RESULTS
Histopathology demonstrated a solitary benign syringoma. HPV-20 and HPV-23 were present in one clone each, and HPV-5-related HPV-DL332 was present in 9 clones.


CONCLUSIONS
Many human papillomavirus types may be detected in an ocular syringoma.
Assadoullina
A
A
University Eye Hospital Eppendorf, Hamburg, Germany.
Bialasiewicz
A A
AA
de Villiers
E M
EM
Richard
G
G
D017931:DNA Primers / Q000737:chemistry; D004279:DNA, Viral / Q000032:analysis; D005142:Eyelid Neoplasms / Q000473:pathology / Q000821:virology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D013544:Sweat Gland Neoplasms / Q000473:pathology / Q000821:virology*; D018252:Syringoma / Q000473:pathology / Q000821:virology*
D017931:DNA Primers; D004279:DNA, Viral