title: [Functional state of glutamate receptors during treatment with ethanol].
abstract: A growing bulk of experimental data indicates that change of certain neurotransmitter receptors and voltage-dependent ion cannels are characteristic manifestations accompanying ethanol consumption. A likely target for ethanol effects is the glutamate receptors. Glutamate is one of major excitatory neurotransmitter in the mammalian brain. While the acute application of ethanol inhibits glutamate-induced cationic currents, chronic treatment with ethanol leads to an up-regulation of glutamate receptors.
authors.affiliation: North-west Regional Medical Centre Bekhterev, Saint Petersburg, Russia.
authors.forename: S I
authors.initials: SI
authors.lastname: Golovko
authors.forename: S Iu
authors.initials: SIu
authors.lastname: Zefirov
authors.forename: A I
authors.initials: AI
authors.lastname: Golovko
authors.forename: L S
authors.initials: LS
authors.lastname: Shpilenia
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Nekrasov
authors.forename: O I
authors.initials: OI
authors.lastname: Romanenko
mesh_terms: D000437:Alcoholism / Q000503:physiopathology*; D000818:Animals; D000431:Ethanol / Q000633:toxicity*; D006801:Humans; D066298:In Vitro Techniques; D017470:Receptors, Glutamate / Q000187:drug effects / Q000502:physiology*
chemical_list: D017470:Receptors, Glutamate; D000431:Ethanol