Synthesis of selected aminodeoxy analogs of globotriosylceramide.
Four aminodeoxy analogs of globotriosylceramide (6"-, 4"-, 2"-, and 6'-aminodeoxy) were synthesized by glycosylation of 3-O-benzoylated azidosphingosine with the corresponding aminodeoxy-globotriose trichloroacetimidate, followed by reduction of the azido group, N-acylation with 1-adamantaneacetic acid, and removal of the protecting groups.
Hansen
H C
HC
Center for Chemistry and Chemical Engineering, Lund University, Sweden.
Magnusson
G
G
D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D014281:Trihexosylceramides / Q000737:chemistry*
D014281:Trihexosylceramides; C018549:globotriaosylceramide