title: Advances in antimicrobial therapy.
abstract: Despite several decades of improved therapy and prevention of infectious diseases, infectious pathogens remain major causes of morbidity and mortality in humans worldwide. Among the most complex and daunting problems facing medical science is the evolution of antibiotic resistance among many common and once easily-treated infectious agents. This review summarizes the status of newer antimicrobial agents that have utility against pathogens infecting the central nervous system.
authors.affiliation: Department of Pediatrics, University of Utah School of Medicine, Salt Lake City 84132, USA.
authors.forename: A T
authors.initials: AT
authors.lastname: Pavia
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001682:Biological Availability; D002648:Child; D004305:Dose-Response Relationship, Drug; D004352:Drug Resistance, Microbial; D006801:Humans; D008581:Meningitis / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D016920:Meningitis, Bacterial / Q000188:drug therapy; D016921:Meningitis, Fungal / Q000188:drug therapy; D008587:Meningitis, Viral / Q000188:drug therapy; D014481:United States / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000998:Antiviral Agents