An immunologically active arabinogalactan from Tinospora cordifolia.
An arabinogalactan of mean M(r) 2.2 x 10(6) has been isolated from the dried stems of Tinospora cordifolia and examined by methylation analysis, partial hydrolysis and carboxyl reduction. Purified polysaccharide showed polyclonal mitogenic activity against B-cells, their proliferation did not require macrophages.
Chintalwar
G
G
Bio-Organic Division, Bhabha Atomic Research Centre, Trombay, Mumbai, India.
Jain
A
A
Sipahimalani
A
A
Banerji
A
A
Sumariwalla
P
P
Ramakrishnan
R
R
Sainis
K
K
D000276:Adjuvants, Immunologic / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D000818:Animals; D002850:Chromatography, Gel; D005685:Galactans / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology*; D006868:Hydrolysis; D008515:Medicine, Ayurvedic; D008745:Methylation; D051379:Mice; D008934:Mitogens / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology; D010936:Plant Extracts / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D011134:Polysaccharides / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology
D000276:Adjuvants, Immunologic; D005685:Galactans; D008934:Mitogens; D010936:Plant Extracts; D011134:Polysaccharides; C005653:arabinogalactan