[Guideline for diagnosis and management of hyperlipidemia for prevention of atherosclerosis in Japan].
Coronary heart disease (CHD) mortality and plasma cholesterol level have increased in Japan. There has been evidence indicating that cholesterol-lowering is effective in secondary and primary prevention of CHD. Hypercholesterolemia has been defined as over 220 mg/dl, and over 140 mg/dl for LDL-cholesterol. These levels were determined on the base of the evidence observed in Japan. The subjects are divided as follows, A: no CHD and no other risk factors, B: no CHD and at least one risk factor, C: manifest CHD. The treatment levels of LDL-cholesterol are 140 mg/dl for category A, 120 mg/dl for B and 100 mg/dl for C. Although drug therapy may be necessary when LDL-cholesterol level is over 120 mg/dl in category C, life-style modification is most important in category A and B.
Teramoto
T
T
Department of Internal Medicine, Teikyo University School of Medicine.
D003324:Coronary Artery Disease / Q000517:prevention & control*; D006801:Humans; D006949:Hyperlipidemias / Q000175:diagnosis* / Q000628:therapy*; D017410:Practice Guidelines as Topic