title: Is it safe to administer thrombolytic therapy to myocardial infarction patients soon after laparoscopic cholecystectomy?
abstract: Thrombolytic therapy is usually contraindicated after abdominal surgery because of the risk of bleeding. We report a case of a 73-year-old woman who was admitted because of anterior wall acute myocardial infarction (AMI) two weeks after laparoscopic cholecystectomy. She was treated with streptokinase, aspirin and heparin and subsequently developed a hematoma at the site of the removed gallbladder. Our observation suggests that thrombolytic therapy for anterior AMI, two weeks after laparoscopic cholecystectomy, should be considered as a relative contraindication and an optional treatment in this life-threatening situation.
authors.affiliation: Cardiology Department, Soroka Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel. sergio_k@reim.org.il
authors.forename: S
authors.initials: S
authors.lastname: Kobal
authors.forename: G
authors.initials: G
authors.lastname: Orlov
authors.forename: H
authors.initials: H
authors.lastname: Gilutz
authors.forename: C
authors.initials: C
authors.lastname: Cafri
authors.forename: A
authors.initials: A
authors.lastname: Battler
authors.forename: J
authors.initials: J
authors.lastname: Leor
mesh_terms: D000368:Aged; D017081:Cholecystectomy, Laparoscopic; D000075202:Contraindications; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006406:Hematoma / Q000209:etiology; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy*; D015912:Thrombolytic Therapy / Q000009:adverse effects