title: How do general practitioners diagnose and manage patients with transient monocular loss of vision of sudden onset?
abstract: Symptoms of transient loss of vision in one eye differ widely. They may have different causes and therefore carry a different prognosis. We studied the influence of differences between characteristics of transient monocular blindness on the diagnosis and management by general practitioners (GPs). A postal questionnaire, was sent to 1600 GPs in The Netherlands along with four case vignettes describing a case history of a 56-year-old man with transient monocular disturbances of vision of sudden onset. We introduced random permutations in the following four elements of the history: partial or complete visual field involved, blurring or blacking out of vision, attacks lasting minutes or hours, and patients having covered either eye during the attack or not. Respondents were asked about the probable diagnosis and the preferred management. For each of the 16 permutations about 50 responses were obtained (overall response rate 54%). Ischemic transient monocular blindness (ITMB) was chosen as the most likely diagnosis in 49%. In 12% primary ocular disease was suspected. Involvement of the complete visual field, blacking out of vision, and short attacks were identified as independent predictors of a diagnosis of ITMB. A diagnosis of ITMB would have resulted in referral to a specialist in 72% of patients. Antithrombotic treatment would have been initiated in only 36% of ITMB patients. GPs consider brief attacks with complete blacking out of vision most typical for retinal ischemia. They refer only three-quarters of patients with probable ITMB to a specialist and start antithrombotic medication in only one-third of these patients. Therefore further education with regard to transient monocular blindness is needed.
authors.affiliation: Department of Neurology, University Medical Center Utrecht, The Netherlands. R.C.J.M.Donders@neuro.azu.nl
authors.forename: R C
authors.initials: RC
authors.lastname: Donders
authors.forename: L J
authors.initials: LJ
authors.lastname: Kappelle
authors.forename: A
authors.initials: A
authors.lastname: Algra
authors.forename: G W
authors.initials: GW
authors.lastname: van Dijk
authors.forename: J
authors.initials: J
authors.lastname: van Gijn
mesh_terms: D020757:Amaurosis Fugax / Q000175:diagnosis* / Q000628:therapy*; D005194:Family Practice / Q000379:methods*; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D012017:Referral and Consultation; D011795:Surveys and Questionnaires
chemical_list: D005343:Fibrinolytic Agents