title: Progressive multifocal leukoencephalopathy demonstrating contrast enhancement on MRI and uptake of thallium-201: a case report.
abstract: We describe a patient with AIDS who presented with focal neurological symptoms, and who had contrast-enhancing brain lesions on MRI which demonstrated increased thallium-201 uptake on SPECT. These findings were consistent with lymphoma; however, brain biopsy established a diagnosis of progressive multifocal leukoencephalopathy (PML). To our knowledge, this is the first reported case of PML with increased thallium-201 uptake on brain SPECT.
authors.affiliation: Russell H. Morgan Department of Radiology, Johns Hopkins Medical School, Baltimore, MD 21287, USA.
authors.forename: J D
authors.initials: JD
authors.lastname: Port
authors.forename: S
authors.initials: S
authors.lastname: Miseljic
authors.forename: R R
authors.initials: RR
authors.lastname: Lee
authors.forename: S Z
authors.initials: SZ
authors.lastname: Ali
authors.forename: T L
authors.initials: TL
authors.lastname: Nicol
authors.forename: W
authors.initials: W
authors.lastname: Royal
authors.forename: B B
authors.initials: BB
authors.lastname: Chin
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D013794:Thallium Radioisotopes