title: Appearance of frontal midline theta activity in patients with generalized anxiety disorder.
abstract: The appearance of frontal midline theta activity (Fm&theta;), recognized as distinct EEG theta rhythm in the frontal midline area during performance of a mental task, reflects feelings of relief from anxiety in humans. In the present study, EEGs were recorded, and the Hamilton Rating Scale for Anxiety and the state anxiety scale of Spielberger's State-Trait Anxiety Inventory were evaluated once a week in 28 patients with generalized anxiety disorder. The Taylor Manifest Anxiety Scale and the trait anxiety scale of Spielberger's State-Trait Anxiety Inventory were used to assess anxiety before and after the tests. The present results suggest that the appearance of Fm&theta; might be closely related to an improvement in the anxiety symptoms associated with generalized anxiety disorder.
authors.affiliation: Department of Neuropsychiatry, Yamaguchi University School of Medicine, Ube, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Suetsugi
authors.forename: Y
authors.initials: Y
authors.lastname: Mizuki
authors.forename: I
authors.initials: I
authors.lastname: Ushijima
authors.forename: T
authors.initials: T
authors.lastname: Kobayashi
authors.forename: K
authors.initials: K
authors.lastname: Tsuchiya
authors.forename: T
authors.initials: T
authors.lastname: Aoki
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D014151:Anti-Anxiety Agents / Q000008:administration & dosage; D001008:Anxiety Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D001143:Arousal / Q000187:drug effects / Q000502:physiology; D004569:Electroencephalography / Q000187:drug effects; D005260:Female; D005625:Frontal Lobe / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory; D011340:Problem Solving / Q000187:drug effects / Q000502:physiology; D013826:Theta Rhythm
chemical_list: D014151:Anti-Anxiety Agents; D006993:Hypnotics and Sedatives