title: Giant cisterna chyli: MRI depiction with gadolinium-DTPA enhancement.
abstract: OBJECTIVE
  To demonstrate the use of MRI with Gadolinium-DTPA enhancement in the diagnosis of giant cisterna chyli.
  
  
  METHODS
  The study consisted of contrast enhanced MRI with ultrasound and CT correlation in three patients with a giant cisterna chyli. An analysis of the morphology, location and post-contrast MR signal characteristics in relation to time was performed.
  
  
  RESULTS
  Cisterna chyli has a characteristic lobulated morphology and location but the unenhanced MRI appearances are not specific. The post-Gadolinium-DTPA MRI appearances are critically dependent on the time elapsed after injection of contrast medium. Within the first 5 min, there is no enhancement at all, but by 10 min there is early layering of contrast medium evident, which by 30 min produces a clear fluid-fluid level. Delayed images at 4-5 h demonstrate a uniform enhancement of the cisternal contents producing a homogeneous intermediate signal. All of these features are best visualized on T1 fast saturation sequences.
  
  
  CONCLUSIONS
  MRI with Gadolinium-DTPA enhancement is valuable in confirming the nature of the lymphatic ducts in the retroperitoneal space and helps to differentiate these normal structures from alternative lesions such as lymphadenopathy and tumour recurrence.
authors.affiliation: Department of Radiology, Robert Jones & Agnes Hunt Orthopaedic & District Hospital, Oswestry, Shropshire, SY10 7AG, UK.
authors.forename: K C
authors.initials: KC
authors.lastname: Lee
authors.forename: V N
authors.initials: VN
authors.lastname: Cassar-Pullicino
mesh_terms: D000293:Adolescent; D000368:Aged; D003287:Contrast Media; D003937:Diagnosis, Differential; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013897:Thoracic Duct / Q000000981:diagnostic imaging / Q000473:pathology*
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA