title: Expression and cellular localization of the Toucan protein during Drosophila oogenesis.
abstract: The toucan (toc) gene is required in the germline for somatic cell patterning during Drosophila oogenesis. To better understand the function of toc, we performed a detailed analysis of the distribution of the Toucan protein during oogenesis. Toc expression is restricted to the germline cells and shows a dynamic distribution pattern throughout follicle development. Mislocalization of the Toc protein in mutant follicles in which the microtubule network is altered indicates that microtubules play a role in Toc localization during oogenesis.
authors.affiliation: Institut National de la Santé et de la Recherche Médicale U384, Laboratoire de Biochimie, UFR Médecine, 28, place Henri Dunant, 63001, Clermont-Ferrand, France.
authors.forename: M
authors.initials: M
authors.lastname: Grammont
authors.forename: G
authors.initials: G
authors.lastname: Berson
authors.forename: B
authors.initials: B
authors.lastname: Dastugue
authors.forename: J L
authors.initials: JL
authors.lastname: Couderc
mesh_terms: D000818:Animals; D000906:Antibodies; D004330:Drosophila; D005260:Female; D015870:Gene Expression; D005982:Glutathione Transferase / Q000378:metabolism; D019476:Insect Proteins / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism; D009865:Oocytes / Q000378:metabolism; D009866:Oogenesis; D010053:Ovary; D011817:Rabbits; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000276:immunology / Q000378:metabolism; D013347:Subcellular Fractions
chemical_list: D000906:Antibodies; D019476:Insect Proteins; D011993:Recombinant Fusion Proteins; D005982:Glutathione Transferase