Immobilization of TADDOL with a High Degree of Loading on Porous Silica Gel and First Applications in Enantioselective Catalysis.
The versatile TADDOL moiety has been immobilized for the first time on an inorganic support (highly porous silica gel). This gives access to Ti - Lewis acids (see picture), which turn out to be very efficient in two standard enantioselective reactions. X=OiPr, OTos.
Heckel
A
Laboratorium für Organische Chemie der Eidgenössischen Technischen Hochschule Zürich ETH-Zentrum, Universitätstrasse 16, CH-8092 Zürich (Switzerland).
Seebach
D