[Comparative analysis of reperfusion time in primary angioplasty vs thrombolysis. Success vs time].
We studied 398 patients with diagnosis of acute myocardial infarction who arrived within the first six hours of symptom onset that were treated with thrombolysis or primary angioplasty, they were divided in two groups: Group 1 (n = 198), those treated with 1.5 million U of streptokinase over 60 min and Group 2 (n = 200), those treated with primary angioplasty. In Group 1 the "pain-door" time was 3.7 +/- 1.7 hs vs 3.8 +/- 2.4 hs in group 2 (p = NS). The "door-needle" time was 48 +/- 12 min. compared with the "door-balloon" time of 84 +/- 30 min (p < 0.001). In Group 1, 154 (77.6%) of the patients had clinical of reperfusion after thrombolysis, 58 of them underwent coronary angiography and had an infarct related artery (IRA) patency rate of 45.3%. In Group 2 the IRA patency rate was 85.5% (p < 0.005).


CONCLUSIONS
Thrombolysis was achieved in a lesser period of time but our findings showed that primary angioplasty was more effective obtaining a TIMI 3 flow.
Martínez Sánchez
C
C
Unidad de Cuidados Coronarios, Instituto Nacional de Cardiologìa Ignacio Chávez, México, D.F.
Martínez
C
C
Lasses
A
A
de la Peña
E
E
Ramírez
J
J
Luna
J
J
González
H
H
Chuquiure
E
E
Juárez Herrera
U
U
Martínez Ríos
M A
MA
González Romero
S
S
Lupi
E
E
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D015425:Myocardial Reperfusion; D013300:Streptokinase / Q000627:therapeutic use*; D013997:Time Factors
D005343:Fibrinolytic Agents; D013300:Streptokinase