title: [The role of deformability of endothelial cells in the arterial response to shear tension].
abstract: Treatment of the femoral artery luminal surface with glutaraldehyde dimere or dithiosuccinimidyl propionate reduced or eliminated flow-induced dilation, the responses to acetylcholine and the ATP being preserved. The findings suggest that the endothelial cells perceive changes in shear stress and that the cell stiffness is a factor subject to the influence of the magnitude of flow-induced arterial dilation.
authors.affiliation: Cardiological Research-Industrial Complex, Moscow, Russia.
authors.forename: A M
authors.initials: AM
authors.lastname: Mel'kumiants
authors.forename: S A
authors.initials: SA
authors.lastname: Balashov
mesh_terms: D000818:Animals; D002415:Cats; D002417:Cattle; D048429:Cell Size / Q000187:drug effects; D002478:Cells, Cultured; D019281:Dimerization; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D005263:Femoral Artery / Q000187:drug effects / Q000502:physiology*; D005976:Glutaral / Q000494:pharmacology; D006801:Humans; D012039:Regional Blood Flow; D013314:Stress, Mechanical
chemical_list: D005976:Glutaral