title: Zopiclone use during pregnancy.
abstract: OBJECTIVE
  One of my patients, whom I had treated with a 2-week course of zopiclone for insomnia, conceived while using the medication. She is concerned. How should I advise her?
  
  
  CONCLUSIONS
  Based on available, albeit limited, evidence, zopiclone does not appear to be a major human teratogen.
authors.affiliation: Hospital for Sick Children, Toronto.
authors.forename: O
authors.initials: O
authors.lastname: Diav-Citrin
authors.forename: B
authors.initials: B
authors.lastname: Okotore
authors.forename: K
authors.initials: K
authors.lastname: Lucarelli
authors.forename: G
authors.initials: G
authors.lastname: Koren
mesh_terms: D000014:Abnormalities, Drug-Induced; D000328:Adult; D053961:Azabicyclo Compounds; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D010879:Piperazines / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced*; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy*
chemical_list: D053961:Azabicyclo Compounds; D006993:Hypnotics and Sedatives; D010879:Piperazines; C515050:zopiclone