[A study of genetic character and foreign OMT/PGH gene integration in transgenic swine].
By using isotopic and non-isotopic in situ hybridization on chromosomes, the locus on chromosomes of foreign OMT/PGH gene was analyzed in eight transgenic pigs (G0, G1,G2 and G3). The research result is as follows: (1) The foreign genes could integrated on chromosomes of pig and the foreign integrated randomly; (2) the foreign genes integrated on chromosomes were transmissible through generations; (3) the locus on chromosomes of foreign gene was relatively stable in alternation of generations in transgenic swine.
Fan
J H
JH
Institute of Animal and Veterinary, HAAS, Wuhan.
Wei
Q X
QX
Chen
Q X
QX
Li
K
K
D000818:Animals; D030801:Animals, Genetically Modified; D002874:Chromosome Mapping; D005260:Female; D017403:In Situ Hybridization; D008297:Male; D013552:Swine / Q000235:genetics*