title: [An experimental validation of pharmacological agents to arrest the vestibulo-autonomic syndrome (motion sickness)].
abstract: The results of development and experimental evaluation of the efficiency of pharmacological means of cupping the vestibulo-vegetative syndrome in man are presented. A model and procedure of evaluation of pharmacological cupping of the Vestibulo-vegetative syndrome are developed. The intramuscular injection of the mixture containing ephedrine, promethazine hydrochloride and strychnine (25, 50, and 1 mg, respectively) appeared most effective.
authors.affiliation: N. A. Semashko Moscow Medical Stomatologic Institute, Russia.
authors.forename: V S
authors.initials: VS
authors.lastname: Shashkov
authors.forename: A R
authors.initials: AR
authors.lastname: Kotovskaia
authors.forename: O I
authors.initials: OI
authors.lastname: Orlov
authors.forename: M I
authors.initials: MI
authors.lastname: Koloteva
authors.forename: A V
authors.initials: AV
authors.lastname: Shashkov
authors.forename: S K
authors.initials: SK
authors.lastname: Karsanova
mesh_terms: D003312:Coriolis Force; D004359:Drug Therapy, Combination; D004809:Ephedrine / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D009041:Motion Sickness / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control* / Q000523:psychology; D011398:Promethazine / Q000008:administration & dosage / Q000009:adverse effects; D013331:Strychnine / Q000008:administration & dosage / Q000009:adverse effects; D013577:Syndrome; D013997:Time Factors; D014724:Vestibular Function Tests / Q000706:statistics & numerical data
chemical_list: D011398:Promethazine; D004809:Ephedrine; D013331:Strychnine