Successful primary radiation therapy of adenoid cystic carcinoma of the lung.
Adenoid cystic carcinoma is a distinctive malignant neoplasm generally arising from minor salivary glands, that arises infrequently as a primary tumor in the lung. Surgery has been considered the primary treatment, with radiotherapy generally utilized as adjuvant or palliative treatment. We report a patient in whom primary radiotherapy was sucessfully applied to treat adenoid cystic carcinoma involving the distal trachea, carina, and both main stem bronchi. A total dose of 66 Gy was delivered in 2-Gy fractions over a 7-week period. Clinically and histologically complete remission was achieved without evidence of disease during a 27-month follow up.
Müller
A
A
Department of Radiation Therapy and Radiation Oncology, University of Düssseldorf, Germany.
Stockamp
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B
Schnabel
T
T
D000328:Adult; D001984:Bronchial Neoplasms / Q000532:radiotherapy; D003528:Carcinoma, Adenoid Cystic / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D008297:Male; D011879:Radiotherapy Dosage; D014057:Tomography, X-Ray Computed; D014134:Tracheal Neoplasms / Q000532:radiotherapy; D016896:Treatment Outcome