[Clinical profile and prognosis of bacteremia in patients with cirrhosis based on the Child-Pugh classification].
The characteristics of 70 cases of bacteremia in cirrhotic patients were studied according to the Child-Pugh classification as severity marker of liver involvement. Factors influencing on prognosis were determined. For a comparative analysis, 1,006 cases of bacteremia in non-cirrhotic patients were included. Sixteen patients corresponded to group A, 23 to group B and 31 to group C in the Child-Pugh classification. Patients in group A had a predominance of extra-enteric microorganisms, mainly Staphylococcus aureus (37.5%; p = 0.02), well-defined source (urinary tract, respiratory tract, skin) and good prognosis (mortality rate 6.2%). In contrast, patients in group C had a high recovery rate of Escherichia coli (41.9%) and pneumococcus (19.3%), undetermined source (51.6%; p = 0.05), ascites (83.9%), with or without concomitant peritonitis (41.1%; p = 0.03) and poor prognosis (mortality rate 48.3%; p = 0.008). The characteristics of patients in group B were similar to those of patients in group C but prognosis was as in patients in group A. The immediate mortality rate in the studied patients was 26%. The parameter which best predicted survival in the multivariate analysis was the Child-Pugh classification.
Monte Secades
R
R
Servicio de Medicina Interna, Complexo Hospitalario Xeral-Calde, Lugo.
Casariego Vales
E
E
Mateos Colino
A
A
Rigueiro Veloso
T
T
Alonso García
P
P
Rodríguez Feijoo
A
A
Corredoira Sánchez
J
J
D000328:Adult; D000368:Aged; D016470:Bacteremia / Q000150:complications* / Q000175:diagnosis / Q000401:mortality; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000145:classification / Q000150:complications* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D013997:Time Factors