Expression and cellular localization of the Toucan protein during Drosophila oogenesis.
The toucan (toc) gene is required in the germline for somatic cell patterning during Drosophila oogenesis. To better understand the function of toc, we performed a detailed analysis of the distribution of the Toucan protein during oogenesis. Toc expression is restricted to the germline cells and shows a dynamic distribution pattern throughout follicle development. Mislocalization of the Toc protein in mutant follicles in which the microtubule network is altered indicates that microtubules play a role in Toc localization during oogenesis.
Grammont
M
M
Institut National de la Santé et de la Recherche Médicale U384, Laboratoire de Biochimie, UFR Médecine, 28, place Henri Dunant, 63001, Clermont-Ferrand, France.
Berson
G
G
Dastugue
B
B
Couderc
J L
JL
D000818:Animals; D000906:Antibodies; D004330:Drosophila; D005260:Female; D015870:Gene Expression; D005982:Glutathione Transferase / Q000378:metabolism; D019476:Insect Proteins / Q000235:genetics / Q000276:immunology / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism; D009865:Oocytes / Q000378:metabolism; D009866:Oogenesis; D010053:Ovary; D011817:Rabbits; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000276:immunology / Q000378:metabolism; D013347:Subcellular Fractions
D000906:Antibodies; D019476:Insect Proteins; D011993:Recombinant Fusion Proteins; D005982:Glutathione Transferase