title: New treatment strategies in advanced prostate cancer.
abstract: The treatment of advanced prostate cancer has evolved rapidly in the last 5 years. Therapeutic options for patients with advanced disease, once essentially limited to the use of androgen deprivation, have expanded to include a number of interventions, including secondary hormonal manipulations, chemotherapy, and a variety of investigational approaches. Novel therapeutic approaches in prostate cancer patients are likely to be undertaken in patients with disease that is at or below the limits of detection by current imaging technology, so novel methods will be essential to the successful evaluation and use of these agents.
authors.affiliation: Department of Medicine, University of California San Francisco, USA. smalle@medicine.ucsf.edu
authors.forename: E J
authors.initials: EJ
authors.lastname: Small
authors.forename: D M
authors.initials: DM
authors.lastname: Reese
mesh_terms: D000726:Androgen Antagonists / Q000627:therapeutic use; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017209:Apoptosis; D002455:Cell Division / Q000187:drug effects; D003952:Diagnostic Imaging; D006801:Humans; D007167:Immunotherapy; D008297:Male; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*
chemical_list: D000726:Androgen Antagonists; D018931:Antineoplastic Agents, Hormonal