title: The magnetic resonance imaging of musculoskeletal hemorrhage.
abstract: Hematomas in the extremities can present clinically as a soft tissue mass. Hematomas can usually be distinguished from neoplasia on MR by the signal patterns of hemoglobin breakdown products, which are dependent on the chemical bonding and oxidation state of hemoglobin iron. Beginning with a discussion of relevant atomic electronic structure, this review will examine how oxyhemoglobin, deoxyhemoglobin, methemoglobin, and hemosiderin, the principal iron compounds occurring in the various stages of a hematoma, affect its appearance on MRI.
authors.affiliation: Department of Radiology, University of Florida College of Medicine, P.O. Box 100374, Gainesville, FL 32610, USA.
authors.forename: C H
authors.initials: CH
authors.lastname: Bush
mesh_terms: D003937:Diagnosis, Differential; D006406:Hematoma / Q000175:diagnosis* / Q000378:metabolism; D006454:Hemoglobins / Q000737:chemistry / Q000378:metabolism; D006485:Hemosiderin / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D009140:Musculoskeletal Diseases / Q000175:diagnosis* / Q000378:metabolism
chemical_list: D006454:Hemoglobins; D006485:Hemosiderin