title: Prosthetic reconstruction of the femur for primary bone sarcoma.
abstract: The survival of patients and implants, complications and functional outcome were reviewed in 25 consecutive femoral endoprosthetic reconstructions for treatment of primary bone sarcoma. The diagnosis was chondrosarcoma in 11, osteosarcoma in 10, MFH in 3 and Ewing's tumour in 1. Median follow up was 64 months (34 to 219) and median age at operation was 29 years (10 to 70). Twelve remained disease free at review. One had amputation for local recurrence and another was alive with metastases. 11 patients died at a median of 13 months (5 to 128); 8 from metastatic disease and 3 from other causes. Four implants were revised, at a median of 95 months (53 to 136); two for fractures of the stem and two for aseptic loosening. Three implants had radiological evidence of loosening at a median of 43 months (34 to 49). Fourteen patients had significant complications. The median functional score using the Musculoskeletal Tumour Society system was 68%. In our experience, prosthetic reconstruction of the femur does not compromise survival, although there is a significant complication rate.
authors.affiliation: Department of Orthopaedic Surgery, Western Infirmary, Glasgow, UK. C.Gerrand@clinmed.gla.ac.uk
authors.forename: C H
authors.initials: CH
authors.lastname: Gerrand
authors.forename: D
authors.initials: D
authors.lastname: Currie
authors.forename: P
authors.initials: P
authors.lastname: Grigoris
authors.forename: R
authors.initials: R
authors.lastname: Reid
authors.forename: D L
authors.initials: DL
authors.lastname: Hamblen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000601:surgery*; D002648:Child; D002813:Chondrosarcoma / Q000601:surgery; D005260:Female; D005266:Femoral Neoplasms / Q000601:surgery*; D018219:Histiocytoma, Benign Fibrous / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012516:Osteosarcoma / Q000601:surgery; D011475:Prosthesis Failure; D012189:Retrospective Studies; D012509:Sarcoma / Q000601:surgery*; D013977:Tibia