title: Prostate cancer and dietary carotenoids.
abstract: This population-based case-control study investigated associations between prostate cancer risk and dietary intake of the carotenoids beta-carotene and lycopene and their major plant food sources, including carrots, green leafy vegetables, and tomato-based foods. The study was carried out in Auckland, New Zealand, during 1996-1997 and recruited 317 prostate cancer cases and 480 controls. The authors found that dietary intake of beta-carotene and its main vegetable sources was largely unassociated with prostate cancer risk, whereas intake of lycopene and tomato-based foods was weakly associated with a reduced risk. These results suggest that in contrast to the findings regarding many types of cancers, vegetables rich in beta-carotene are not protective against prostate cancer. However, lycopene from tomato-based foods was found to be associated with a small reduction in risk.
authors.affiliation: Department of Community Health, University of Auckland, New Zealand.
authors.forename: A E
authors.initials: AE
authors.lastname: Norrish
authors.forename: R T
authors.initials: RT
authors.lastname: Jackson
authors.forename: S J
authors.initials: SJ
authors.lastname: Sharpe
authors.forename: C M
authors.initials: CM
authors.lastname: Skeaff
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015982:Bias; D002338:Carotenoids / Q000008:administration & dosage*; D016022:Case-Control Studies; D018552:Daucus carota; D004032:Diet; D004034:Diet Surveys; D006801:Humans; D016015:Logistic Models; D018551:Solanum lycopersicum; D008297:Male; D008875:Middle Aged; D009520:New Zealand / Q000453:epidemiology; D011159:Population Surveillance; D011446:Prospective Studies; D011471:Prostatic Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D012307:Risk Factors; D014675:Vegetables
chemical_list: D002338:Carotenoids