Molecular cloning and characterization of a cDNA encoding a transferrin homolog from Bombyx mori.
We isolated a cDNA representing a message that was strongly induced by injection with E. coli in Bombyx mori. The 2160 bp cDNA has an open reading frame of 644 amino acids and the deduced product a predicted molecular mass of 71 kDa. The cDNA sequence shared high homology with the transferrins known so far, and its deduced peptide had unique features of transferrins, that is, sites of cystein residues and iron binding. We suggest that the B. mori transferrin plays an important role in the self-defense system.
Yun
E Y
EY
Department of Sericulture and Entomology, National Institute of Agricultural Science and Technology, RDA, Suwon, Korea.
Kang
S W
SW
Hwang
J S
JS
Goo
T W
TW
Kim
S H
SH
Jin
B R
BR
Kwon
O Y
OY
Kim
K Y
KY
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D012831:Bombyx / Q000235:genetics*; D003001:Cloning, Molecular; D018076:DNA, Complementary; D004926:Escherichia coli / Q000235:genetics; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D017386:Sequence Homology, Amino Acid; D014168:Transferrin / Q000235:genetics*
D018076:DNA, Complementary; D014168:Transferrin