Detection of florfenicol resistance genes in Escherichia coli isolated from sick chickens.
Florfenicol is an antibiotic approved for veterinary use in cattle in the United States in 1996. Although this drug is not used in poultry, we have detected resistance to florfenicol in clinical isolates of avian Escherichia coli. Molecular typing demonstrated that the florfenicol resistance gene, flo, was independently acquired and is plasmid encoded.
Keyes
K
K
Department of Microbiology and Parasitology, College of Veterinary Medicine, The University of Georgia, Athens, Georgia 30602, USA.
Hudson
C
C
Maurer
J J
JJ
Thayer
S
S
White
D G
DG
Lee
M D
MD
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002645:Chickens / Q000382:microbiology; D004352:Drug Resistance, Microbial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000662:veterinary*; D005798:Genes, Bacterial; D010957:Plasmids / Q000235:genetics; D011201:Poultry Diseases / Q000382:microbiology; D013839:Thiamphenicol / Q000031:analogs & derivatives* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; C035534:florfenicol; D013839:Thiamphenicol