title: Migration of polyethylene wear debris in one type of uncemented femoral component with circumferential porous coating: an autopsy study of 5 femurs.
abstract: This autopsy study analyzed the migration of polyethylene wear debris adjacent to uncemented femoral components with circumferential porous coating. Five femoral specimens retrieved at autopsy from 3 patients were investigated. Two stems were 40% porous coated, 2 were 80% porous coated, and 1 was 100% porous coated. The implants' time in situ ranged from 53 to 132 months (average, 94.8 months). All patients were followed clinically and radiographically until death. Radiographically, 3 of the stems were bone ingrown with proximal bone loss, 1 stem was mainly fibrous encapsulated, and 1 stem was completely fibrous encapsulated. Histologic examination of bone adjacent to the middle and distal sections of the femoral implant revealed no polyethylene wear debris or granulation tissue in any of the specimens. In 2 bone-ingrown cases, a small number of polyethylene particles and small areas of granulation tissue were present at the proximal level. This granulation tissue, however, did not cause major osteolysis. The findings in this study imply that circumferential porous coating of cementless femoral components could prevent distal migration of polyethylene wear debris along the bone-implant interface in both bone-ingrown and fibrous-encapsulated femoral implants.
authors.affiliation: Orthopaedic University Hospital, Goettingens, Germany.
authors.forename: M
authors.initials: M
authors.lastname: von Knoch
authors.forename: C A
authors.initials: CA
authors.lastname: Engh
authors.forename: C J
authors.initials: CJ
authors.lastname: Sychterz
authors.forename: C A
authors.initials: CA
authors.lastname: Engh
authors.forename: H G
authors.initials: HG
authors.lastname: Willert
mesh_terms: D000368:Aged; D020099:Coated Materials, Biocompatible; D005269:Femur / Q000473:pathology; D005548:Foreign-Body Migration / Q000473:pathology*; D006622:Hip Prosthesis; D006801:Humans; D020959:Polyethylene; D011474:Prosthesis Design
chemical_list: D020099:Coated Materials, Biocompatible; D020959:Polyethylene