New Efficient Multicomponent Reactions with C-C Coupling for Combinatorial Application in Liquid and on Solid Phase.
Up to nine C-C bonds are formed selectively from up to seven components starting from an alkene, a haloarene, and a dienophile [Eq. (1)]. A comparison of liquid- and solid-phase reactions reveals a surprising superiority of the solid-phase reaction.
de Meijere A
Institute für Organische und Anorganische Chemie der Universität, D-37077 Göttingen (Germany).
Nüske
H
Es-Sayed
M
Labahn
T
Schroen
M
Bräse
S