title: In-vitro fertilization in a spontaneous cycle: easy, cheap and realistic.
abstract: The results of in-vitro fertilization in natural cycles (NIVF) in women with tubal infertility at our department are presented. The study had a prospective design. We needed 75 cycles in 50 patients to obtain one oocyte from each patient. Successful oocyte recovery rate was 67% per started cycle and 82% per oocyte retrieval. Thirty-five embryos were transferred and resulted in four ongoing pregnancies (5.3% per cycle, 6.5% per oocyte retrieval, 11.4% per embryo transfer and 11.4% per embryo). Six patients who participated in the study made a second attempt at NIVF. Five of them conceived of which four were ongoing. Cumulative ongoing pregnancy rates are 9. 8% per cycle, 11.9% per oocyte retrieval, 19.5% per embryo transfer and 19.5% per embryo. We conclude that NIVF is an easy, cheap and realistic method to obtain a pregnancy for patients with tubal infertility.
authors.affiliation: Institute for Endocrinology, Reproduction and Metabolism, IVF Center, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.
authors.forename: R M
authors.initials: RM
authors.lastname: Janssens
authors.forename: C B
authors.initials: CB
authors.lastname: Lambalk
authors.forename: J P
authors.initials: JP
authors.lastname: Vermeiden
authors.forename: R
authors.initials: R
authors.lastname: Schats
authors.forename: J
authors.initials: J
authors.lastname: Schoemaker
mesh_terms: D000328:Adult; D005187:Fallopian Tubes / Q000002:abnormalities; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007247:Infertility, Female / Q000000981:diagnostic imaging / Q000628:therapy*; D007986:Luteinizing Hormone / Q000097:blood; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone