title: Treatment of a large periapical lesion with loss of labial cortical plate using GTR: a case report.
abstract: Following endodontic treatment, a large periapical lesion (9.0 mm x 9.0 mm) at a maxillary central incisor was treated with demineralized freeze-dried bone allograft (DFDBA) using the principles of guided tissue regeneration. The physical barrier was removed 6 months postsurgical. The cortical alveolar plate was observed to be completely reconstructed. Histologic evaluation demonstrated lamellar bone surrounding DFDBA particles. Radiographic follow-up 1 year posttreatment demonstrated complete resolution of the periapical radiolucency.
authors.affiliation: Department of Periodontology, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.
authors.forename: F
authors.initials: F
authors.lastname: Brugnami
authors.forename: J T
authors.initials: JT
authors.lastname: Mellonig
mesh_terms: D000328:Adult; D016301:Alveolar Bone Loss / Q000601:surgery*; D001861:Bone Regeneration; D016025:Bone Transplantation / Q000379:methods*; D005612:Freeze Drying; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D007180:Incisor; D008297:Male; D008437:Maxilla