[Phosphoinositide-specific phospholipase C gamma 1--a key protein for signal transduction, triggered by growth factors].
The review is devoted to the participation of phospholipase C gamma 1 in cell signaling. A great attention is paid to mechanisms of activation of phospholipase C gamma and its interaction with other signaling molecules. The role of phospholipase C gamma binding to cytoskeletal elements in cell signaling is discussed.
Medvedeva
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ND
Institute of Cytology, Russian Academy of Sciences, St. Petersburg. Medved@link.cytspb.rssi.ru
D003599:Cytoskeleton / Q000378:metabolism; D004789:Enzyme Activation; D004815:Epidermal Growth Factor / Q000378:metabolism*; D043265:Phosphatidylinositol Diacylglycerol-Lyase; D015398:Signal Transduction; D010738:Type C Phospholipases / Q000378:metabolism*
D004815:Epidermal Growth Factor; D010738:Type C Phospholipases; D043265:Phosphatidylinositol Diacylglycerol-Lyase