title: Cytokeratin fragment 19 (CYFRA 21-1) in healthy smokers.
abstract: Two hundred and ninety-three normal female non-smokers, 268 normal male non-smokers, and 224 normal male smokers were included in our comparative study to determine possible effect of smoking on the serum levels of cytokeratin fragment 19 (CYFRA 21-1). Immunoradiometric assay (IRMA) was used, and the results revealed that the mean +/- SD CYFRA 21-1 levels in the 293 normal female non-smokers, 268 normal male non-smokers, and 224 normal male smokers were 1.28 +/- 0.82, 1.38 +/- 0.74, and 1.47 +/- 0.62 ng/ml, respectively. There is no significantly statistical difference in the CYFRA 21-1 level among the three groups. In conclusion, we suggest that smoking has no effect on the serum levels of CYFRA 21-1.
authors.affiliation: Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan.
authors.forename: C H
authors.initials: CH
authors.lastname: Kao
authors.forename: J F
authors.initials: JF
authors.lastname: Hsieh
authors.forename: Y J
authors.initials: YJ
authors.lastname: Ho
authors.forename: S C
authors.initials: SC
authors.lastname: Tsai
authors.forename: J K
authors.initials: JK
authors.lastname: Lee
mesh_terms: D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D005260:Female; D006304:Health Status; D006801:Humans; D053539:Keratin-19; D007633:Keratins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012907:Smoking / Q000097:blood*
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D053539:Keratin-19; C102012:antigen CYFRA21.1; D007633:Keratins