TGF-beta receptors and DNA repair genes, coupled targets in a pathway of human colon carcinogenesis.
Markowitz
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Howard Hughes Medical Institute, Ireland Cancer Center and Department of Medicine, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, USA. sxm10@o.cwru.edu
D048868:Adaptor Proteins, Signal Transducing; D017209:Apoptosis; D020137:Base Pair Mismatch; D002352:Carrier Proteins; D003110:Colonic Neoplasms / Q000209:etiology* / Q000235:genetics; D004260:DNA Repair / Q000235:genetics*; D016147:Genes, Tumor Suppressor; D006801:Humans; D000070957:MutL Protein Homolog 1; D009154:Mutation; D009363:Neoplasm Proteins / Q000235:genetics; D009687:Nuclear Proteins; D017346:Protein Serine-Threonine Kinases; D000077294:Receptor, Transforming Growth Factor-beta Type II; D018125:Receptors, Transforming Growth Factor beta / Q000037:antagonists & inhibitors / Q000235:genetics*; D015398:Signal Transduction
D048868:Adaptor Proteins, Signal Transducing; D002352:Carrier Proteins; C501486:MLH1 protein, human; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; D018125:Receptors, Transforming Growth Factor beta; D017346:Protein Serine-Threonine Kinases; D000077294:Receptor, Transforming Growth Factor-beta Type II; D000070957:MutL Protein Homolog 1