[Atypical primary biliary cirrhosis or autoimmune cholangitis?].
The term autoimmune cholangitis is used for a disease with clinical and pathological features of primary biliary cirrhosis (PBC), lack of anti-mitochondrial antibodies (AMA), presence of anti-nuclear antibodies (ANA), and good response to immunosuppresive therapy. The current knowledge of this condition is limited and it is not established whether or not it is a different syndrome from the CBP. We report a 51-year-old woman with chronic cholestasis, histological features of PBC, negative AMA and positive peripheral fluorescent ANA pattern, without response to prednisone.
Primo
J
J
Unidad de Digestivo, Hospital de Sagunto, Valencia. jprimo@san.gva.es
Miralles
A
A
Ferrando
J
J
Albert
A
A
Julve
R
R
Gómez
A
A
García
L
L
D000974:Antibodies, Antinuclear / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000175:diagnosis*; D001706:Biopsy; D002761:Cholangitis / Q000175:diagnosis* / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D008099:Liver / Q000473:pathology; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis*; D008875:Middle Aged; D008928:Mitochondria / Q000276:immunology
D000974:Antibodies, Antinuclear; D001323:Autoantibodies