[Genetic analysis of Italian hematologic patients candidates for bone marrow transplantation from unrelated donors].
Frequencies of HLA-A, -B and -DR antigens and haplotypes were determined in 1945 Italian patients suffering from hematologic diseases and requiring bone marrow transplantation from unrelated donors. These frequencies were compared with those obtained from the Italian bone marrow donor population. No significant differences were found when considering the number of comparisons made, suggesting that the genetic structure of the Italian patients is not different from that of the Italian donor population.
Rendine
S
S
Servizio di Immunologia dei Trapianti, Ospedale Molinette, Torino.
Barbanti
M
M
Sacchi
N
N
Curtoni
E S
ES
D016026:Bone Marrow Transplantation; D005819:Genetic Markers; D015234:HLA-A Antigens / Q000235:genetics; D015235:HLA-B Antigens / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics; D006402:Hematologic Diseases / Q000235:genetics*; D006650:Histocompatibility Testing; D006801:Humans; D007558:Italy; D014019:Tissue Donors
D005819:Genetic Markers; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D006684:HLA-DR Antigens