A novel polymorphism in the human interleukin-13 (IL-13) promoter.
Using PCR-SSCP and automated nucleotide sequencing we have identified a novel single nucleotide C --> T polymorphism in the human IL-13 promoter, at position -1055 relative to the transcription start site. Allele frequency analysis in a population of normal cord blood donors indicated frequencies of 0.833 (C) and 0. 167 (T).
Laundy
G J
GJ
Division of Transplantation Sciences, University of Bristol, UK.
Spink
C F
CF
Keen
L J
LJ
Wood
N A
NA
Bidwell
J L
JL
D001483:Base Sequence; D006801:Humans; D018793:Interleukin-13 / Q000235:genetics*; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D018807:Polymorphism, Single-Stranded Conformational; D011401:Promoter Regions, Genetic; D012689:Sequence Homology, Nucleic Acid
D018793:Interleukin-13