title: Ischaemic complications with intra-aortic balloon counter-pulsation: incidence and management.
abstract: The most important limitation of the use of the intra-aortic balloon pump is the risk of vascular complications. The aim of this study was to identify risk factors and aspects of diagnosis and management that may decrease the risk of vascular morbidity associated with intra-aortic balloon pumps. Risk factors, surgical techniques, complications and other variables were retrospectively evaluated in 524 patients who had an intra-aortic balloon pump inserted between January 1988 and December 1998. Of the total, 140 (26.7%) patients with an intra-aortic balloon pump had ischaemic complications that needed surgery. The mean age was 65.2 +/-12.3 years (66.7% men and 27.5% women). The mortality rate was 28.1%. The mortality for patients with ischaemic vascular complications was significantly higher than in those patients without (59.6 versus 30.1%, P = 0.001). One-hundred and eight (77.2%) ischaemic complications occurred during therapy with an intra-aortic balloon pump and 32 (22.8%) complications after intra-aortic balloon pumping had been stopped. Thromboembolectomy was required in 71 (50.7%) patients. Associated surgical procedures were performed in 69 (49.3%) patients. A history of peripheral vascular disease (43.6 versus 23.6%, P < 0.05) and the presence of diabetes mellitus (49.2 versus 16.9%, P < 0.05) increased the risk of limb ischaemia significantly. Limb ischaemia remains the major complication after intra-aortic balloon pump insertion. Independent predictors for vascular complications included peripheral vascular disease and diabetes. Intra-aortic balloon pump removal and thrombectomy is usually sufficient to provide revascularization. Identification of subclinical disease may aid in the management of subsequent acute limb ischaemia.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Georg-August University, Göttingen, Germany. hsirbu@gwdg.de
authors.forename: H
authors.initials: H
authors.lastname: Sirbu
authors.forename: T
authors.initials: T
authors.lastname: Busch
authors.forename: I
authors.initials: I
authors.lastname: Aleksic
authors.forename: M
authors.initials: M
authors.lastname: Friedrich
authors.forename: H
authors.initials: H
authors.lastname: Dalichau
mesh_terms: D000367:Age Factors; D000368:Aged; D002318:Cardiovascular Diseases / Q000601:surgery; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000175:diagnosis; D019468:Disease Management; D005121:Extremities / Q000098:blood supply* / Q000601:surgery; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis; D015994:Incidence; D007423:Intra-Aortic Balloon Pumping / Q000009:adverse effects*; D007511:Ischemia / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality / Q000628:therapy; D008297:Male; D016491:Peripheral Vascular Diseases / Q000150:complications / Q000175:diagnosis; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D017131:Thrombectomy; D013923:Thromboembolism / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality / Q000628:therapy