title: Antiplatelet use in interventional cardiology.
abstract: Thrombosis within the target vessel is one of the most feared complications associated with coronary intervention, as it is often associated with severe adverse clinical sequelae. This thrombosis is mediated via the activation and aggregation of platelets and therefore considerable effort has been directed at ways of inhibiting platelet function. It is now mandatory to consider the use of two and often three different antiplatelet agents, particularly when intracoronary stents are inserted. Using these regimes, many of the adverse clinical outcomes associated with platelet activation can be reduced.
authors.affiliation: Regional Cardiothoracic Centre, Blackpool Victoria Hospital, Whinney Heys Road, Blackpool, Lancashire FY3 8NR, UK.
authors.forename: A
authors.initials: A
authors.lastname: Brodison
authors.forename: R
authors.initials: R
authors.lastname: Katira
authors.forename: R S
authors.initials: RS
authors.lastname: More
authors.forename: A
authors.initials: A
authors.lastname: Chauhan
mesh_terms: D013504:Cardiovascular Surgical Procedures / Q000009:adverse effects*; D003327:Coronary Disease / Q000188:drug therapy; D003328:Coronary Thrombosis / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors
chemical_list: D010975:Platelet Aggregation Inhibitors; D019039:Platelet Glycoprotein GPIIb-IIIa Complex