Matched unrelated donor bone marrow transplantation in leukocyte adhesion deficiency.
The severe phenotype of leukocyte adhesion deficiency is a rare, congenital disorder of leukocyte function that is usually fatal in the first few years of life. Allogeneic hematopoietic stem cell transplantation currently offers the only curative approach for this disease. We describe the first successful matched unrelated donor bone marrow transplant in an infant with leukocyte adhesion deficiency.
Mancias
C
C
Department of Pediatrics, University of Texas Health Science Center at San Antonio 78284-7810, USA.
Infante
A J
AJ
Kamani
N R
NR
D001521:Behavior Therapy; D016026:Bone Marrow Transplantation; D005260:Female; D006085:Graft Survival; D006086:Graft vs Host Disease / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D018370:Leukocyte-Adhesion Deficiency Syndrome / Q000628:therapy*; D014184:Transplantation, Homologous / Q000379:methods