Biochemical effects of garlic protein on lipid metabolism in alcohol fed rats.
Garlic protein is a very good hypolipidemic agent. In the present study the water soluble protein fraction of garlic was investigated for its effect on hyperlipidemia induced by alcohol (3.76 g/kg. body wt./day). The hypolipidemic action is mainly due to an increase in cholesterol degradation to bile acids and neutral sterols and mobilization of triacyl glycerols in treated rats. Garlic protein (500 mg./kg body wt./day) showed significant hypolipidemic action comparable with a standard dose of gugu-lipid (50 mg./kg. body wt./day).
Rajasree
C R
CR
Department of Biochemistry, University of Kerala, Thiruvananthapuram, India.
Rajamohan
T
T
Augusti
K T
KT
D000818:Animals; D000431:Ethanol / Q000633:toxicity; D005737:Garlic / Q000737:chemistry*; D006949:Hyperlipidemias / Q000139:chemically induced / Q000178:diet therapy* / Q000378:metabolism; D000960:Hypolipidemic Agents / Q000494:pharmacology; D050356:Lipid Metabolism; D008297:Male; D014674:Plant Proteins, Dietary / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D017207:Rats, Sprague-Dawley
D000960:Hypolipidemic Agents; D014674:Plant Proteins, Dietary; D000431:Ethanol