title: Resistance to mercury and antimicrobial agents in Streptococcus mutans isolates from human subjects in relation to exposure to dental amalgam fillings.
abstract: Resistance to cefuroxime, penicillin, tetracycline, and mercury is reported for 839 Streptococcus mutans isolates from 209 human study subjects. The MICs of these drugs did not differ for isolates from one dental amalgam group and two nonamalgam subsets: a group with no known exposure to amalgam and a group whose members had their amalgam fillings removed.
authors.affiliation: National Public Health Institute, Antimicrobial Research Laboratory, Finland.
authors.forename: J
authors.initials: J
authors.lastname: Leistevuo
authors.forename: H
authors.initials: H
authors.lastname: Järvinen
authors.forename: M
authors.initials: M
authors.lastname: Osterblad
authors.forename: T
authors.initials: T
authors.lastname: Leistevuo
authors.forename: P
authors.initials: P
authors.lastname: Huovinen
authors.forename: J
authors.initials: J
authors.lastname: Tenovuo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003723:Dental Amalgam / Q000009:adverse effects / Q000494:pharmacology*; D003793:Dental Restoration, Permanent; D004352:Drug Resistance, Microbial; D006801:Humans; D008628:Mercury / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D013291:Streptococcus / Q000187:drug effects* / Q000502:physiology
chemical_list: D000900:Anti-Bacterial Agents; D003723:Dental Amalgam; D008628:Mercury