title: Synthesis and antimicrobial activity of bis[6-phenyl-4-methyl-3-substituted-pyrazo[4,5-d] pyrazol-1-yl]thioketones.
abstract: New bis[6-phenyl-4-methyl-3-substituted-pyrazo[4,5-d] pyrazol-1-yl]thioketones have been obtained in good yield by the reaction of thiocarbohydrazine with 1-phenyl-3-methyl-4-acetyl/benzoyl-pyrazol-5-one, followed by cyclization of the intermediate. The new compounds exhibit excellent antimicrobial activity.
authors.affiliation: Department of Chemistry, Institute of Science, Mumbai, India.
authors.forename: M S
authors.initials: MS
authors.lastname: Chande
authors.forename: N V
authors.initials: NV
authors.lastname: Thakkar
authors.forename: D V
authors.initials: DV
authors.lastname: Patil
mesh_terms: D000995:Antitubercular Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D006834:Hydrazines / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests
chemical_list: D000995:Antitubercular Agents; D006834:Hydrazines; C011368:thiocarbohydrazide