title: Beclomethasone diproprionate inhalation as a treatment for post-intubation tracheal stenosis.
abstract: A 67-year-old man was intubated for one week and suffered from wheeze and dyspnoea three months after the extubation. Bronchoscopy revealed tracheal stenosis by a web, which subsequent biopsy showed to be granulation tissue. The stenosis was removed by laser therapy but the stenosis soon returned. As cardiac function was poor, beclomethasone diproprionate (BDP) inhalation therapy (1200 micrograms daily) was started and proved successful. Discontinuation of inhalation therapy resulted in restenosis. Steroid inhalation therapy may be able to control post-intubation tracheal stenosis caused by granulation tissue.
authors.affiliation: Department of Internal Medicine, National Kanazawa Hospital, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Abo
authors.forename: M
authors.initials: M
authors.lastname: Fujimura
authors.forename: Y
authors.initials: Y
authors.lastname: Kibe
authors.forename: H
authors.initials: H
authors.lastname: Kida
authors.forename: T
authors.initials: T
authors.lastname: Matsuda
mesh_terms: D000280:Administration, Inhalation; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D001507:Beclomethasone / Q000008:administration & dosage*; D006097:Granulation Tissue / Q000601:surgery; D006801:Humans; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D053685:Laser Therapy; D008297:Male; D012008:Recurrence; D014135:Tracheal Stenosis / Q000188:drug therapy* / Q000209:etiology / Q000601:surgery
chemical_list: D000893:Anti-Inflammatory Agents; D001507:Beclomethasone