The effect of Bromelia pinguin extract on the pregnant rat uterus.
A non proteinaceous extract of Bromelia pinguin fruit was examined for activity on the rat uterus in vivo and in vitro. The in vivo experiments involved pregnant rats given the extract intraperitoneally. These rats did not abort nor were any foetal deformities observed. The extract inhibited spontaneous activity of the pregnant rat uterus in vitro. These results do not support the claimed folklore use of the plant as an abortifacient. The extract of Bromelia pinguin fruit may have some utero-active compound which inhibits uterine motility.
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Department of Obstetrics, Gynaecology, University of the West Indies, Jamaica.
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Gossell-Williams
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D000019:Abortifacient Agents / Q000494:pharmacology; D000818:Animals; D005260:Female; D066298:In Vitro Techniques; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar; D014590:Uterine Contraction / Q000187:drug effects*
D000019:Abortifacient Agents; D010936:Plant Extracts