title: [Chromosome homologies between human and Francois' monkey (Semnopithecus francoisi) established by chromosome painting].
abstract: Chromosomal homologies were established between human and Francois' monkey (Semnopithecus francoisi, 2n = 44) by chromosome painting with chromosome-specific DNA probes of all human chromosomes except the Y. Except for human chromosome 1, 2, 6, 16 and 19 probes which gave signals on two nonhomologous S. francoisi chromosomes respectively, all other probes each hybridized to a single chromosome. Only two S. francoisi chromosomes (No. 12 and No. 21) were each labelled by two separate probes (14 and 15, 21 and 22, respectively). In total, 23 human chromosome-specific probed detected 30 homologous chromosomes and chromosomal segments in the haploid S. francoisi genome. The results indicated a high degree of conservation of chromosomal synteny between human and this langur. Only some chromosomal rearrangements occurred in this langur. Comparison of the hybridization patterns of human painting probes on this langur with the data on other primates suggested that Asian langurs were karyotypically more closely related to each other than to African langurs.
authors.affiliation: Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming.
authors.forename: W H
authors.initials: WH
authors.lastname: Nai
authors.forename: R Q
authors.initials: RQ
authors.lastname: Liu
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Chen
authors.forename: J H
authors.initials: JH
authors.lastname: Wang
mesh_terms: D000818:Animals; D002521:Cercopithecus / Q000235:genetics*; D020223:Chromosome Painting; D006801:Humans