title: [Epidemic outbreak of tularemia in Palencia].
abstract: BACKGROUND
  Tularemia can become a health problem after its recent emergence in Spain.
  
  
  OBJECTIVE
  To describe the clinico-epidemiologic characteristics of a tularemia outbreak occurred in Palencia (October 1997 to March 1998).
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  A clinico-epidemiologic survey was conducted. The Chi square test and the Student "t" test were used and a logistic regression analysis was made. The diagnosis was made by serology (microagglutination or macroagglutination) or culture.
  
  
  RESULTS
  There were 151 cases; 74.5% of cases were confirmed or likely. The ulceroglandular was the most common clinical form of the disease (49%) and 23.2% of patients required hospital admission; 93.4% of patients had exposure to hares, and 86.7% of them handled them. Higher risk practices included skinning (adjusted OR: 3.9; 95% CI [1.03-14.7]; p = 0.04) and cutting/cooking (adjusted OR: 2.7; 95% CI [1.01-6.7]; p = 0.03). Streptomycin therapy was used for 51.6% of cases.
  
  
  CONCLUSIONS
  The clinico-epidemiologic surveillance of this disease in Spain is necessary.
authors.affiliation: Servicio Territorial de Sanidad y Bienestar Social de Palencia, Sección de Epidemiología.
authors.forename: C
authors.initials: C
authors.lastname: Andrés Puertas
authors.forename: M L
authors.initials: ML
authors.lastname: Mateos Baruque
authors.forename: I
authors.initials: I
authors.lastname: Burón Lobo
authors.forename: M J
authors.initials: MJ
authors.lastname: González Megido
authors.forename: C
authors.initials: C
authors.lastname: Rebollo Cuadrado
authors.forename: L A
authors.initials: LA
authors.lastname: Sangrador Arenas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D002648:Child; D003627:Data Interpretation, Statistical; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D013307:Streptomycin / Q000627:therapeutic use; D014406:Tularemia / Q000188:drug therapy / Q000453:epidemiology*
chemical_list: D000900:Anti-Bacterial Agents; D013307:Streptomycin