Signal transduction: hair brains in bacterial chemotaxis.
The conserved cytoplasmic domains of bacterial chemotaxis receptors are a fibrous arrangement of alpha-helical coiled coils that look a lot like hair. Such bundles of alpha-helical filaments mediate sensory-motor responses in all prokaryotic cells. How do they work? Very nearly perfectly is probably as good an answer as any.
Stock
J
J
Department of Molecular Biology, Princeton University, New Jersey 08544, USA.
Levit
M
M
D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins / Q000737:chemistry / Q000502:physiology*; D002633:Chemotaxis / Q000502:physiology*; D019281:Dimerization; D004926:Escherichia coli / Q000502:physiology; D029968:Escherichia coli Proteins; D008565:Membrane Proteins / Q000737:chemistry / Q000502:physiology; D000072236:Methyl-Accepting Chemotaxis Proteins; D008958:Models, Molecular; D010766:Phosphorylation; D011487:Protein Conformation; D011494:Protein Kinases / Q000737:chemistry / Q000502:physiology; D011499:Protein Processing, Post-Translational; D017434:Protein Structure, Tertiary; D012475:Salmonella / Q000502:physiology; D013329:Structure-Activity Relationship
D001426:Bacterial Proteins; C489103:CheW protein, E coli; D029968:Escherichia coli Proteins; D008565:Membrane Proteins; D000072236:Methyl-Accepting Chemotaxis Proteins; C051236:CheW protein, Bacteria; C069656:CheB protein, Bacteria; D011494:Protein Kinases