[Relationship between the clinical course of bronchial asthma from childhood to adulthood (deterioration/improvement), bronchial hyperreactivity and incidence of house dust mite allergens in households of persons treated for atopic bronchial asthma as children].
The aim of the study was to determine the impact of the exposition to house dust mite allergens or its lack on clinical state of asthma in young adults treated in their childhood for atopic bronchial asthma. The concentration of house mite allergen was studied with the method of Acarex test (detection of guanine--excretory product of house dust mites) in the flats of 55 persons treated for atopic asthma before adolescence. There was significant difference (p < 0.006) between the clinical course of asthma (improvement) in persons living in flats free of house dust mite allergens and those living in flats infested with mites. House dust mite allergens were present significantly more frequently in flats of persons with a low histamine threshold (19 of 20 examined flats) than in flats of persons with a high histamine threshold or without hyperreactivity to histamine (6 of 20 examined flats).
Szmidt
M
M
II Kliniki Instytutu Gruźlicy i Chorób Płuc w Warszawie.
Zawistowska
E
E
D000328:Adult; D000367:Age Factors; D000818:Animals; D001249:Asthma / Q000209:etiology*; D016535:Bronchial Hyperreactivity / Q000209:etiology*; D002648:Child; D018450:Disease Progression; D004391:Dust / Q000032:analysis*; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis* / Q000706:statistics & numerical data; D004784:Environmental Monitoring; D005260:Female; D006801:Humans; D008297:Male; D008925:Mites
D004391:Dust