title: Reliability of water proton chemical shift temperature calibration for focused ultrasound ablation therapy.
abstract: Our purpose in this work was to assess the reliability of the calibration coefficient for magnetic resonance water proton chemical shift temperature mapping. Over a six month period, the calibration coefficient was measured 15 times in several different phantoms. A highly linear relationship between water proton chemical shift and temperature change was found. The average temperature calibration coefficient determined from all studies was 0.009+/-0.001 ppm/degrees C. Four of the 15 studies were conducted on the same day using the same phantom. The average temperature calibration coefficient of these four studies was 0.0096+/-0.0001 ppm/degrees C.
authors.affiliation: Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA. wu.tao@mayo.edu
authors.forename: T
authors.initials: T
authors.lastname: Wu
authors.forename: K R
authors.initials: KR
authors.lastname: Kendell
authors.forename: J P
authors.initials: JP
authors.lastname: Felmlee
authors.forename: B D
authors.initials: BD
authors.lastname: Lewis
authors.forename: R L
authors.initials: RL
authors.lastname: Ehman
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D006801:Humans; D008279:Magnetic Resonance Imaging; D019047:Phantoms, Imaging; D011522:Protons; D015203:Reproducibility of Results; D012983:Soft Tissue Neoplasms / Q000628:therapy; D013696:Temperature; D014464:Ultrasonic Therapy / Q000379:methods* / Q000706:statistics & numerical data; D014867:Water
chemical_list: D011522:Protons; D014867:Water