Memnobotrins and memnoconols: novel metabolites from Memnoniella echinata.
Four novel metabolites have been isolated from a rice culture of Memnoniella echinata (JS6308) by solvent extraction and radial silica chromatography. The structures were elucidated by spectroscopic techniques, and the absolute stereochemistry of memnobotrin A determined by X-ray crystallography.
Hinkley
S F
SF
Department of Chemistry and Biochemistry, Joint Institute for Food Safety and Applied Nutrition, University of Maryland, College Park 20742, USA.
Fettinger
J C
JC
Dudley
K
K
Jarvis
B B
BB
D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018360:Crystallography, X-Ray; D005233:Fatty Alcohols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005285:Fermentation; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D003904:Mitosporic Fungi / Q000378:metabolism*; D008968:Molecular Conformation; D014407:Tumor Cells, Cultured
D000903:Antibiotics, Antineoplastic; D001572:Benzofurans; D005233:Fatty Alcohols; D006576:Heterocyclic Compounds, 4 or More Rings; C403867:memnobotrin A; C403868:memnobotrin B; C403869:memnoconol