Percutaneous implantation of a Port-Catheter System using the left subclavian artery.
OBJECTIVE
To evaluate the safety and feasibility of a percutaneous Port-Catheter System (PCS) implanted via the subclavian artery (SCA) for regional chemotherapy or chemoembolization of thoracic, abdominal, and pelvic malignant tumors.


METHODS
Percutaneous puncture of the SCA was performed in 256 patients with thoracic, abdominal, or pelvic malignant tumors; then a catheter was inserted into the target artery. After the first transcatheter chemotherapy or chemoembolization with an emulsion of lipiodol and anticancer agents, an indwelling catheter was introduced with its tip placed in the target artery and its end subcutaneously connected to a port.


RESULTS
The procedure was successfully completed in all 256 cases (100%). The indwelling catheter tip was satisfactorily placed in the target arteries in 242 cases (98%). Complications attributable to the procedure occurred in 20 (7.8%) cases, including pneumothorax (n = 10, 4%), hemothorax (n = 1, 0.4%), infections in the pocket (n = 4, 1.6%), and hematoma at the puncture site (n = 5, 2%). There were no severe sequelae or deaths. The duration of PCS usage was 1-36 months (median 9.5 months). During the course of treatment, occlusion of the target artery occurred in 20 cases (7.8%). Dislocation of the tip of the indwelling catheter occurred in 12 cases (4.7%); in 10 of the 12, the tip of the indwelling catheter was repositioned into the target artery. In all 10 cases no large symptomatic hematomas developed after the PCS was removed.


CONCLUSIONS
Percutaneous PCS implantation via the left SCA, a relatively new procedure, is a safe and less invasive treatment approach than surgical placement for malignancies.
Chen
Y
Y
Department of Radiology, Nanfang Hospital, Guangzhou 510515, P.R. China.
He
X
X
Chen
W
W
Lu
W
W
Mei
Q
Q
Zeng
Q
Q
Li
Y
Y
D000008:Abdominal Neoplasms / Q000188:drug therapy; D000328:Adult; D002408:Catheters, Indwelling; D016461:Chemoembolization, Therapeutic; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D010386:Pelvic Neoplasms / Q000188:drug therapy; D013348:Subclavian Artery; D013899:Thoracic Neoplasms / Q000188:drug therapy; D013997:Time Factors