title: [Hepatobiliary cystadenoma with mesenchymal stroma: a hormone dependent tumor. Report of five cases with immunohistochemical study of hormone receptors].
abstract: Hepatobiliary cystadenomas with mesenchymal stroma are rare neoplasms, which occur only in females; they have a strong tendency to recur and a potential for malignant transformation. Microscopic features are characteristic but clinical findings are highly variable and laboratory data non specific. We report 5 cases with immunohistochemical study, showing the characteristics of mesenchymal stromal cells: myofibroblastic phenotype and expression of progesterone receptors in all cases and estrogen receptors in 3 out of 5 cases. These results point out the possible hormonal dependance of this tumor.
authors.affiliation: Service d'Anatomie Pathologique, Hôpital Pellegrin, place Amélie-Raba-Léon, 33076 Bordeaux.
authors.forename: M
authors.initials: M
authors.lastname: Pedram-Canihac
authors.forename: B
authors.initials: B
authors.lastname: Le Bail
authors.forename: J
authors.initials: J
authors.lastname: Rivel
authors.forename: J
authors.initials: J
authors.lastname: Blanc
authors.forename: J
authors.initials: J
authors.lastname: Saric
authors.forename: P
authors.initials: P
authors.lastname: Bioulac-Sage
mesh_terms: D000328:Adult; D001661:Biliary Tract Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D003537:Cystadenoma / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D008875:Middle Aged; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*; D017154:Stromal Cells / Q000473:pathology
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone