title: UCT1072s, new antitumor antibiotics with topoisomerase II mediated DNA cleavage activity, from Aspergillus sp.
authors.affiliation: Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Japan.
authors.forename: A
authors.initials: A
authors.lastname: Asai
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashita
authors.forename: K
authors.initials: K
authors.lastname: Ando
authors.forename: S
authors.initials: S
authors.lastname: Kakita
authors.forename: K
authors.initials: K
authors.lastname: Kita
authors.forename: Y
authors.initials: Y
authors.lastname: Suzuki
authors.forename: A
authors.initials: A
authors.lastname: Mihara
authors.forename: T
authors.initials: T
authors.lastname: Ashizawa
authors.forename: T
authors.initials: T
authors.lastname: Mizukami
authors.forename: H
authors.initials: H
authors.lastname: Nakano
mesh_terms: D000880:Anthraquinones / Q000302:isolation & purification* / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification* / Q000494:pharmacology; D001230:Aspergillus / Q000378:metabolism*; D004249:DNA Damage; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005285:Fermentation; D005663:Furans / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D059005:Topoisomerase II Inhibitors; D014407:Tumor Cells, Cultured
chemical_list: D000880:Anthraquinones; D000903:Antibiotics, Antineoplastic; D004791:Enzyme Inhibitors; D005663:Furans; D059005:Topoisomerase II Inhibitors; C403877:UCT 1072M1; C403878:UCT 1072M2