title: Considerations on the changes of certain immunologic parameters in occupational allergic bronchial asthma due to textile fibers.
abstract: The changes of some immunologic parameters such as IgG, IgA and IgM, the C3 complement, the circulating immune complexes and alpha 1--antitrypsin were investigated in 75 patients with occupational allergic bronchial asthma to textile fibers as compared with 50 apparently healthy controls with no occupational exposure to textile fibers. It was observed that IgG and IgA decreased significantly while IgM increased. Likewise C3 decreased in all patients with occupational allergic bronchial asthma (OABA) as compared with the controls an CIC increased significantly. The determinations carried out demonstrated a parallelism of action in the immune response.
authors.affiliation: N. Malaxa Clinical Hospital, Bucharest, Romania.
authors.forename: C M
authors.initials: CM
authors.lastname: Mitrea
authors.forename: M
authors.initials: M
authors.lastname: Cojocaru
mesh_terms: D000328:Adult; D000936:Antigen-Antibody Complex / Q000097:blood; D001249:Asthma / Q000209:etiology / Q000276:immunology*; D003176:Complement C3 / Q000032:analysis; D006801:Humans; D007113:Immunity, Innate; D007136:Immunoglobulins / Q000097:blood; D008875:Middle Aged; D009784:Occupational Diseases / Q000209:etiology / Q000276:immunology*; D013784:Textiles / Q000009:adverse effects*; D000515:alpha 1-Antitrypsin / Q000032:analysis
chemical_list: D000936:Antigen-Antibody Complex; D003176:Complement C3; D007136:Immunoglobulins; D000515:alpha 1-Antitrypsin