title: Two allelic forms of the aureolysin gene (aur) within Staphylococcus aureus.
abstract: Proteinases of Staphylococcus aureus are emerging as potential virulence factors which may be involved in the pathogenecity of staphylococcal diseases. We describe here the structure of the gene encoding the metalloproteinase referred to as aureolysin. This gene occurs in two allelic forms and is strongly conserved among S. aureus strains, implying the possibility that the proteinase may have important housekeeping functions.
authors.affiliation: Department of Microbiology and Immunology, Institute of Molecular Biology, Jagiellonian University, 31-120 Krakow, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Sabat
authors.forename: K
authors.initials: K
authors.lastname: Kosowska
authors.forename: K
authors.initials: K
authors.lastname: Poulsen
authors.forename: A
authors.initials: A
authors.lastname: Kasprowicz
authors.forename: A
authors.initials: A
authors.lastname: Sekowska
authors.forename: B
authors.initials: B
authors.lastname: van Den Burg
authors.forename: J
authors.initials: J
authors.lastname: Travis
authors.forename: J
authors.initials: J
authors.lastname: Potempa
mesh_terms: D000483:Alleles; D000595:Amino Acid Sequence; D001426:Bacterial Proteins; D001483:Base Sequence; D008666:Metalloendopeptidases / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D013211:Staphylococcus aureus / Q000235:genetics* / Q000472:pathogenicity
chemical_list: D001426:Bacterial Proteins; D008666:Metalloendopeptidases; C115504:aureolysin