Translocation (8;13)(q24.2;q33) in a malignant rhabdoid tumor of the liver.
A case of malignant rhabdoid tumor of the liver associated with hypercalcemia of malignancy was studied. The karyotype of the liver primary was 46,XY,t(8;13)(q24.2;q33)[7]/46,XY[13], and of the brain metastasis 46,XY,t(8;13)(q24;q33)[5]/46,XY,t(7;13)(p14;q22) [3]/46,XY,t(1;2;3)(q25;q21;p21) [2]/46,XY[13], respectively. Band 8q24 was previously reported to be rearranged in two malignant rhabdoid tumors, one renal and one hepatic.
Donner
L R
LR
Department of Pathology, Scott & White Clinic, Temple, TX 76508, USA.
Rao
A
A
Truss
L M
LM
Dobin
S M
SM
D002882:Chromosomes, Human, Pair 13 / Q000235:genetics*; D002898:Chromosomes, Human, Pair 8 / Q000235:genetics*; D006801:Humans; D006934:Hypercalcemia / Q000150:complications; D007223:Infant; D007621:Karyotyping; D008113:Liver Neoplasms / Q000150:complications / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D008297:Male; D018335:Rhabdoid Tumor / Q000150:complications / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D014178:Translocation, Genetic / Q000235:genetics*