title: Small cell carcinoma of the lung: CT findings of parenchymal lesions.
abstract: OBJECTIVE
  The purpose of this study was to describe the CT findings of small cell carcinoma of the lung.
  
  
  METHODS
  CT findings were retrospectively reviewed in 38 patients (34 men, 4 women; aged 46-73 years) with pathologically proven small cell carcinoma.
  
  
  RESULTS
  Tumors were located centrally in 23 cases (61%) and peripherally in 15 cases (39%). Twenty-seven patients had a bulky central mass with encasement of the great vessels or extrinsic compression of the airway (22 central tumors, 5 peripheral tumors). Six patients had peripheral lesions without adenopathy. Five peripheral small cell carcinomas demonstrated peribronchial thickening adjacent to the primary tumor.
  
  
  CONCLUSIONS
  The first sign of small cell carcinoma most typically is a bulky central mass that represents metastasis to the hilar and/or mediastinal lymph nodes. Although no findings specific to peripheral small cell carcinoma are available, small cell carcinoma originating from the peripheral lung parenchyma should be included in the differential diagnosis when peribronchial thickening is associated with the tumor.
authors.affiliation: Department of Radiology, Akita University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Hashimoto
authors.forename: J
authors.initials: J
authors.lastname: Heianna
authors.forename: K
authors.initials: K
authors.lastname: Okane
authors.forename: Y
authors.initials: Y
authors.lastname: Hirano
authors.forename: J
authors.initials: J
authors.lastname: Watarai
mesh_terms: D000368:Aged; D018288:Carcinoma, Small Cell / Q000000981:diagnostic imaging* / Q000556:secondary; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed