title: Maximising the use of HRT: focus on hysterectomised women.
abstract: Hysterectomy is one of the most common gynaecological surgical operations performed in the UK. In addition to causing the early onset of the menopause, hysterectomy can lead some women to be at increased risk of future CHD and osteoporosis owing to declining oestrogen levels. Hysterectomised women are therefore an ideal group to receive hormone replacement therapy (HRT). However, only small numbers of women receive HRT owing to a number of factors, including fear of potential complications and adverse side-effects. Of those women who do receive HRT, compliance with therapy is low. In this article, the authors weigh the benefits of HRT, in terms of relief of menopausal symptoms, and prevention of osteoporosis, Alzheimer's disease and cardiovascular disease, against the known risks. The authors suggest that compliance with HRT could be optimised by profiling patients in general practice and by educating women on the long-term benefits of HRT.
authors.affiliation: Rosen Laboratories, Wynn Institute, Imperial College School of Medicine, St Mary's Hospital Medical School, London, UK.
authors.forename: F S
authors.initials: FS
authors.lastname: Keating
authors.forename: N
authors.initials: N
authors.lastname: Manassiev
authors.forename: J C
authors.initials: JC
authors.lastname: Stevenson
mesh_terms: D000368:Aged; D005260:Female; D020249:Hormone Replacement Therapy / Q000009:adverse effects / Q000379:methods; D006801:Humans; D007044:Hysterectomy / Q000534:rehabilitation*; D008593:Menopause / Q000187:drug effects; D008875:Middle Aged; D010349:Patient Compliance; D012307:Risk Factors