Cytotoxic effect of 2,3-disubstituted chromanones in human cancer cell lines.
Four different synthetic compounds [3-aryl-2-(3-pyridyl)chromanones] were prepared and screened for cytotoxicity against a panel of 29 human cancer cell lines in five different concentrations separately. All compounds displayed cytotoxicity against cancer cell lines and one of them possessed cell type selectivity also.
Vanangamudi
A
A
School of Chemistry, Madurai Kamaraj University, India.
Sudhakar
S
S
Gandhidasan
R
R
D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D002867:Chromones / Q000737:chemistry / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D005260:Female; D006801:Humans; D008297:Male; D013329:Structure-Activity Relationship; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D002867:Chromones