title: "Amphiphilic" Cleavage of gamma-Stannyl Ketones with ATPH/RLi: Application to Enone Fragmentation by the Conjugate Addition - Cleavage Sequence.
abstract: The use of a combined Lewis acid/base system consisting of aluminum tris(2,6-diphenylphenoxide) (ATPH) and MeLi has allowed the electrophilically activated nucleophilic ("amphiphilic") cleavage of C(alpha)-C(beta) bonds in gamma-stannyl ketones. Through combination with the conjugate addition of alpha-stannyl carbanion to enone, this approach constitutes a novel two-step conjugate addition - cleavage sequence that leads to functionalized ketones (see reaction).
authors.affiliation: Department of Chemistry, Graduate School of Science Hokkaido University Sapporo, 060-0810 (Japan).
authors.initials: Y
authors.lastname: Kondo
authors.initials: K
authors.lastname: Kon-I
authors.initials: A
authors.lastname: Iwasaki
authors.initials: T
authors.lastname: Ooi
authors.initials: K
authors.lastname: Maruoka