title: Prognostic value of first polar body morphology on fertilization rate and embryo quality in intracytoplasmic sperm injection.
abstract: The association between oocyte morphology and subsequent fertilization rate and embryo quality in intracytoplasmic sperm injection (ICSI) is subject to considerable controversy. This retrospective study was carried out to investigate a possible prognostic value of first polar body morphology with regard to fertilization rate and embryo quality. A total of 70 consecutive ICSI cases was included in this study. The results showed that classification based on first polar body morphology revealed a significant correlation with fertilization rate (P < 0.025) and embryo quality (P < 0.001). Cytoplasmic criteria showed no correlation in this respect. Present data indicate that ICSI of oocytes with intact well-shaped first polar bodies yields higher fertilization rates and higher quality embryos.
authors.affiliation: Women's General Hospital, IVF-Unit, Lederergasse 47, A-4020 Linz, Austria.
authors.forename: T
authors.initials: T
authors.lastname: Ebner
authors.forename: C
authors.initials: C
authors.lastname: Yaman
authors.forename: M
authors.initials: M
authors.lastname: Moser
authors.forename: M
authors.initials: M
authors.lastname: Sommergruber
authors.forename: O
authors.initials: O
authors.lastname: Feichtinger
authors.forename: G
authors.initials: G
authors.lastname: Tews
mesh_terms: D000328:Adult; D003593:Cytoplasm / Q000502:physiology / Q000648:ultrastructure; D004624:Embryo Transfer; D004622:Embryo, Mammalian / Q000502:physiology*; D005260:Female; D005306:Fertilization; D006801:Humans; D007248:Infertility, Male / Q000628:therapy; D008297:Male; D009865:Oocytes / Q000166:cytology / Q000502:physiology*; D011379:Prognosis; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*; D013084:Sperm-Ovum Interactions