Soybean curd refuse alleviates experimental tumorigenesis in rat colon.
Adult Fischer-344 rats which underwent administration of azoxymethane were fed diets containing soybean curd refuse (SCR) or a high-molecular-weight fraction of soy protein digest (HMF), or Hammarsten casein (CAS) as a protein source over a period of 34 weeks. All the living rats of each group at 22, 28 or 34 weeks were endoscopically inspected for tumor incidence in the colon. SCR turned out to be comparable to HMF in anti-tumorigenicity, or rather better than HMF.
Azuma
N
N
Department of Biological Resource Chemistry, Kyoto Prefectural University, Japan.
Suda
H
H
Iwasaki
H
H
Kanamoto
R
R
Iwami
K
K
D000818:Animals; D001397:Azoxymethane; D002273:Carcinogens; D003110:Colonic Neoplasms / Q000139:chemically induced / Q000188:drug therapy*; D004032:Diet; D004044:Dietary Proteins / Q000494:pharmacology; D008297:Male; D008970:Molecular Weight; D010936:Plant Extracts / Q000627:therapeutic use*; D051381:Rats; D011916:Rats, Inbred F344; D013025:Glycine max
D002273:Carcinogens; D004044:Dietary Proteins; D010936:Plant Extracts; D001397:Azoxymethane