Cicatrizing conjunctivitis associated with paraneoplastic lichen planus.
OBJECTIVE
To report two cases of cicatrizing conjunctivitis associated with paraneoplastic lichen planus.


METHODS
Case reports.


RESULTS
Two patients were examined because of redness and discomfort in both eyes. A 63-year-old woman with follicular, small-cleaved cell lymphoma had cicatrizing conjunctivitis, stomatitis, vulvitis, and skin lesions. A 25-year-old man with malignant thymoma had cicatrizing conjunctivitis, erosive stomatitis, and penile papules. Histopathologic studies of conjunctiva and skin biopsy specimens in the first patient and labial biopsy specimens in the second revealed lichen planus.


CONCLUSIONS
Paraneoplastic lichen planus is a possible cause of cicatrizing conjunctivitis associated with inflammatory skin and mucous membrane disease.
Hahn
J M
JM
Division of Ophthalmology, The Cleveland Clinic Foundation, Ohio 44195, USA.
Meisler
D M
DM
Lowder
C Y
CY
Tung
R C
RC
Camisa
C
C
D000328:Adult; D003231:Conjunctivitis / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000150:complications* / Q000473:pathology; D008224:Lymphoma, Follicular / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000150:complications* / Q000473:pathology; D010390:Pemphigoid, Benign Mucous Membrane / Q000209:etiology* / Q000473:pathology; D010409:Penile Diseases / Q000209:etiology; D012871:Skin Diseases / Q000209:etiology; D013280:Stomatitis / Q000209:etiology; D013945:Thymoma / Q000473:pathology; D013953:Thymus Neoplasms / Q000473:pathology; D014847:Vulvitis / Q000209:etiology