Protein metabolism and the gut.
This paper reviews the recent literature concerning the importance of the gut in extraintestinal protein metabolism. A growing body of evidence suggests that the gut modulates amino acid flux and inter-organ relationships in various metabolic states. This may be particularly true during the absorptive period, when the gut: (1) controls amino acid absorption; (2) may modulate catabolism and uptake for synthesis of absorbed amino acid; and (3) consequently influences the availability of liver and extrasplanchnic amino acids, as well as their pattern and kinetics through portal flow delivery.
Mariotti
F
F
INRA Unité Nutrition Humaine et Physiologie Intestinale, Institut National Agronomique Paris-Grignon, Paris, France.
Huneau
J F
JF
Mahé
S
S
Tomé
D
D
D000596:Amino Acids / Q000378:metabolism; D005243:Feces; D006801:Humans; D007408:Intestinal Absorption; D007422:Intestines / Q000502:physiology*; D009584:Nitrogen / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*
D000596:Amino Acids; D011506:Proteins; D009584:Nitrogen