title: Fibrosing colonopathy in an adult owing to over use of pancreatic enzyme supplements.
abstract: A woman, then in her late 20s, underwent a cholecystectomy in 1962 for gallstone disease and subsequent common bile duct stones were managed endoscopically. However, because of unrelenting pain, a pylorus preserving pancreaticoduodenectomy was done in 1990 and in the following years the patient took large amounts of pancreatic enzyme supplements. She developed large bowel obstruction in 1997 and a right hemicolectomy was undertaken. Histology confirmed fibrosing colonopathy of the ascending colon and caecum. Her pancreatic enzyme dose was reduced and her subsequent course has been uncomplicated.
authors.affiliation: Department of Gastroenterology, The Middlesex Hospital, Mortimer Street, London W1N 8AA, UK.
authors.forename: D S
authors.initials: DS
authors.lastname: Bansi
authors.forename: A
authors.initials: A
authors.lastname: Price
authors.forename: C
authors.initials: C
authors.lastname: Russell
authors.forename: M
authors.initials: M
authors.lastname: Sarner
mesh_terms: D000328:Adult; D003106:Colon / Q000473:pathology*; D003108:Colonic Diseases / Q000139:chemically induced* / Q000473:pathology; D003967:Diarrhea / Q000188:drug therapy / Q000209:etiology; D004334:Drug Administration Schedule; D005260:Female; D005355:Fibrosis; D006801:Humans; D008049:Lipase / Q000009:adverse effects* / Q000627:therapeutic use; D010180:Pancreatectomy
chemical_list: D008049:Lipase