title: B cell leukaemia/lymphoma-2 protein concentrations during normal pregnancy.
abstract: We evaluated bcl-2 protein levels in whole blood, and intraerythrocytic products of lipoperoxidation, in 65 healthy pregnant primiparous women at the end of the first, second and third trimesters of pregnancy. During pregnancy we found a progressive increase in concentrations of bcl-2 and intraerythrocytic products of lipoperoxidation. Moreover, a positive correlation was found between bcl-2 concentrations and lipoperoxidation products, and between bcl-2 protein, E2 and progesterone. The results show that modifications occurring during pregnancy are accompanied by variations of bcl-2 protein.
authors.affiliation: Department of Internal Medicine, University of Messina, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Buemi
authors.forename: A
authors.initials: A
authors.lastname: Allegra
authors.forename: F
authors.initials: F
authors.lastname: Corica
authors.forename: R
authors.initials: R
authors.lastname: D'Anna
authors.forename: A
authors.initials: A
authors.lastname: Ruello
authors.forename: V M
authors.initials: VM
authors.lastname: Jasonni
mesh_terms: D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000378:metabolism; D011247:Pregnancy / Q000378:metabolism*; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism*
chemical_list: D008054:Lipid Peroxides; D019253:Proto-Oncogene Proteins c-bcl-2