Cocaine doses equivalent to those abused by humans occupy most of the dopamine transporters.
Volkow
N D
ND
Medical Department, Brookhaven National Laboratory, Upton, New York 11973, USA. volkow@brain.med.bnl.gov
Gatley
S J
SJ
Fowler
J S
JS
Logan
J
J
Fischman
M
M
Gifford
A N
AN
Pappas
N
N
King
P
P
Vitkun
S
S
Ding
Y S
YS
Wang
G J
GJ
D000818:Animals; D001665:Binding Sites; D001921:Brain / Q000000981:diagnostic imaging; D002352:Carrier Proteins / Q000378:metabolism*; D003042:Cocaine / Q000008:administration & dosage* / Q000378:metabolism*; D019970:Cocaine-Related Disorders / Q000000981:diagnostic imaging*; D050483:Dopamine Plasma Membrane Transport Proteins; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007700:Kinetics; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D014055:Tomography, Emission-Computed
D002352:Carrier Proteins; D050483:Dopamine Plasma Membrane Transport Proteins; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D003042:Cocaine