title: Diphtheria in Latvia, 1986-1996.
abstract: After nearly two decades without a diphtheria case in Latvia, the disease reappeared in 1986. From 1990 to 1996, case counts were highest among adults 40-49 years of age, school-aged children, and adolescents. Nonetheless, the average annualized incidence of disease was highest among infants and preschoolers. In August 1995, mass vaccination efforts began to provide adults 25-60 years of age with at least one dose of vaccine. By the end of the year, a 77% coverage rate was achieved, resulting in a decrease of reported diphtheria cases by 1996. From February to September 1997, special outreach efforts were focused on hard-to-reach populations; as a result, by June 1997, 55% of adults had received three doses of vaccine. While decreases in the incidence of and morbidity from diphtheria have occurred, additional efforts still need to be concentrated on improving vaccination coverage in adults and children <2 years of age and in reducing mortality from diphtheria.
authors.affiliation: Department of Epidemiology of Infectious Diseases, National Environmental Health Center, Rìga, Latvia.
authors.forename: A
authors.initials: A
authors.lastname: Griskevica
authors.forename: P
authors.initials: P
authors.lastname: Ching
authors.forename: G
authors.initials: G
authors.lastname: Russo
authors.forename: J
authors.initials: J
authors.lastname: Kreysler
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D003353:Corynebacterium diphtheriae / Q000276:immunology / Q000302:isolation & purification; D004165:Diphtheria / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control*; D004168:Diphtheria Toxoid / Q000008:administration & dosage; D018563:Disease Notification / Q000706:statistics & numerical data; D004196:Disease Outbreaks / Q000517:prevention & control; D006801:Humans; D007114:Immunization / Q000706:statistics & numerical data; D017589:Immunization Programs; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007844:Latvia / Q000453:epidemiology; D008875:Middle Aged; D009313:National Health Programs
chemical_list: D004168:Diphtheria Toxoid