Double blind, randomised, parallel, prospective, comparative, clinical evaluation of a combination of antispasmodic analgesic Diclofenac + Pitofenone + Fenpiverinium (Manyana vs Analgin + Pitofenone + Fenpiverinium (Baralgan) in biliary, ureteric and intestinal colic.
In this double blind, prospective study, the relative efficacy of Diclofenac + Pitofenone + Fenpiverinium (Manyana) and Analgin + Pitofenone + Fenpiverinium (Baralgan) in 200 patients of biliary, ureteric and intestinal colic was evaluated. Patients were given these coded drugs thrice daily for five days starting from day 0 to day 5. The results of the present clinical evaluation demonstrated that Manyana appeared to be superior to Baralgan in biliary and ureteric colic while it was therapeutically equivalent to Baralgan in reducing the pain intensity in intestinal colic. Both the medications were tolerated well and there were no side-effects reported.
Chaudhary
A
A
Department of G. I. Surgery, GB Pant Hospital, New Delhi.
Gupta
R L
RL
D000293:Adolescent; D000328:Adult; D001577:Benzophenones / Q000627:therapeutic use*; D001660:Biliary Tract Diseases / Q000188:drug therapy*; D003085:Colic / Q000175:diagnosis / Q000188:drug therapy*; D004008:Diclofenac / Q000627:therapeutic use*; D004177:Dipyrone / Q000627:therapeutic use*; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010276:Parasympatholytics / Q000627:therapeutic use*; D010880:Piperidines / Q000627:therapeutic use*; D011446:Prospective Studies; D013997:Time Factors; D014515:Ureteral Diseases / Q000188:drug therapy*
D001577:Benzophenones; D004338:Drug Combinations; D010276:Parasympatholytics; D010880:Piperidines; C118979:manyana; D004008:Diclofenac; D004177:Dipyrone; C002416:fenpiverinium bromide, pitofenone hydrochloride, dipyrone drug combination