title: Subacute cutaneous lupus erythematosus presenting with generalized poikiloderma.
abstract: A 64-year-old woman experienced progressive generalized poikiloderma after an episode of sunburn 4 years earlier. The diagnosis of subacute cutaneous lupus erythematosus (SCLE) was confirmed by the presence of anti-Ro/SS-A and antinuclear antibodies, the histology, and the direct immunofluorescent findings (ie, positive lupus band test and "dust-like" epidermal IgG staining pattern). Poikiloderma has not been previously reported in the spectrum of SCLE. As a major pathomechanism of SCLE, photosensitivity might explain this uncommon clinical manifestation of the disease.
authors.affiliation: Department of Dermatology and Venereology, Alexander's University Hospital, Sofia Faculty of Medicine, Sofia, Bulgaria.
authors.forename: K
authors.initials: K
authors.lastname: Pramatarov
authors.forename: S
authors.initials: S
authors.lastname: Vassileva
authors.forename: L
authors.initials: L
authors.lastname: Miteva
mesh_terms: D017454:Dermatitis, Photoallergic; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged; D011038:Rothmund-Thomson Syndrome / Q000175:diagnosis / Q000473:pathology*; D013471:Sunburn