Long-term administration of heterogenous interferon results in a loss of its biological effect.
Sakaida
I
I
Sugiyama
Y
Y
Kikuchi
M
M
Okita
K
K
D000818:Animals; D003588:Cytopathogenic Effect, Viral / Q000187:drug effects; D004338:Drug Combinations; D005260:Female; D007273:Injections, Intramuscular; D016898:Interferon-alpha / Q000008:administration & dosage*; D016899:Interferon-beta / Q000008:administration & dosage*; D007371:Interferon-gamma / Q000008:administration & dosage*; D008297:Male; D009500:Neutralization Tests; D051381:Rats; D017208:Rats, Wistar; D014721:Vesicular stomatitis Indiana virus / Q000187:drug effects
D004338:Drug Combinations; D016898:Interferon-alpha; D016899:Interferon-beta; D007371:Interferon-gamma