Atypical lipomatous tumors with smooth muscle differentiation: report of two cases.
Two cases of soft-tissue atypical lipomatous tumors with areas of smooth muscle cell differentiation are presented. The patients were a 72-year-old man (Case 1) and a 62-year-old woman (Case 2); their neoplasms were located in the left inguinal region and on the chest, respectively. The adipocytic component in Case 1 contained cells with nuclear atypism and lipoblasts. Case 2 showed only slight nuclear atypism and lacked any lipoblasts. Smooth muscle fascicles were composed of well-differentiated cells with a few mitoses having none or only a slight atypism. They expressed muscle-specific actin and desmin in both cases. No recurrence was recorded during the follow-up time.
Zámecník
M
M
Department of Pathology, General Hospital, Trencín, Slovak Republic.
Michal
M
M
Sulc
M
M
D000199:Actins / Q000032:analysis; D000368:Aged; D003893:Desmin / Q000032:analysis; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008067:Lipoma / Q000737:chemistry / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000737:chemistry / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000473:pathology*
D000199:Actins; D003893:Desmin