title: Signal transduction from the angiotensin II AT2 receptor.
abstract: Recent studies of genetically engineered animals have established a role for the angiotensin II (AT2) receptor in cardiovascular, renal and central functions, as well as in developmental processes. This review summarizes new insights into major AT2 signaling pathways--activation of protein phosphatases, the nitric oxide-cGMP system and phospholipase A2--which have been related to specific cellular responses or functions of this receptor.
authors.affiliation: CNRS UPR415, Institut Cochin de Génétique Moléculaire, 22 rue Méchain, 75014 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Nouet
authors.forename: C
authors.initials: C
authors.lastname: Nahmias
mesh_terms: D000804:Angiotensin II / Q000378:metabolism*; D006801:Humans; D044140:Receptor, Angiotensin, Type 1; D044139:Receptor, Angiotensin, Type 2; D011945:Receptors, Angiotensin / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D044140:Receptor, Angiotensin, Type 1; D044139:Receptor, Angiotensin, Type 2; D011945:Receptors, Angiotensin; D000804:Angiotensin II