[Chinese Han population data obtained from fluorescently detected STR loci-vWA31A, TH01, F13A01, FES, TPOX and CSF1PO].
OBJECTIVE
This paper was designed to evaluate 6 short tandem repeats(STR) loci for their use in forensic personal identification.


METHODS
The allele frequencies and genotype frequencies at 6 tetranucleotide STR loci were determined in a sample of 132 unrelated individuals from a Chinese population of Han nationality in Guangzhou. The PCR products were analysed on 4% denaturing PAGE and detected using fluorescently labeled primers in an automated 377 sequencer(PE). The resultant allele frequencies were compared with other population or race databases.


RESULTS
All the 6 loci (vWA31A, TH01, F13A01,FES, TPOX, CSF1PO) met Hardy-Weinberg equilibrium. No random association of alleles among the 6 loci was noted. Except locus vWA31A, the observed heterozygosities at other 5 loci were significantly lower than those reported in Caucasian and Black population studies. The calculated DP=0.99999,PE=0.9708,pM=1.059 times 10(-5).


CONCLUSIONS
The data obtained can be used in human identity and paternity testing, and in other genetic researches and population investigation.
Jiang
B
B
Center of Molecular Biology, Hengyang Medical College, Hengyang, Hunan, 421001 P.R. China. ydyzyang@public.hy.hn.cn
Guo
J
J
D000483:Alleles; D002681:China / Q000208:ethnology; D002874:Chromosome Mapping; D005453:Fluorescence; D005554:Forensic Medicine; D005787:Gene Frequency; D006801:Humans; D020080:Tandem Repeat Sequences