Cross-species interactions between malaria parasites in humans.
The dynamics of multiple Plasmodium infections in asymptomatic children living under intense malaria transmission pressure provide evidence for a density-dependent regulation that transcends species as well as genotype. This regulation, in combination with species- and genotype-specific immune responses, results in nonindependent, sequential episodes of infection with each species.
Bruce
M C
MC
Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford, OX1 3FY, UK. marian.bruce@ceid.ox.ac.uk
Donnelly
C A
CA
Alpers
M P
MP
Galinski
M R
MR
Barnwell
J W
JW
Walliker
D
D
Day
K P
KP
D000293:Adolescent; D000818:Animals; D002648:Child; D002675:Child, Preschool; D005260:Female; D005838:Genotype; D006801:Humans; D008288:Malaria / Q000276:immunology / Q000469:parasitology*; D017780:Malaria Vaccines; D008297:Male; D010219:Papua New Guinea; D018512:Parasitemia / Q000469:parasitology*; D010961:Plasmodium / Q000235:genetics / Q000502:physiology*; D010963:Plasmodium falciparum / Q000502:physiology; D010965:Plasmodium malariae / Q000502:physiology; D010966:Plasmodium vivax / Q000502:physiology; D013045:Species Specificity
D017780:Malaria Vaccines