title: Angiotropic lymphoma manifesting as a solitary adrenal tumor in a case of ankylosing spondylitis.
abstract: Angiotropic lymphoma is an extremely rare disease characterized by intravascular accumulation of large neoplastic lymphocytes, with the clinical manifestations of fever, skin lesions and neurologic deficits. We report a patient who developed angiotropic lymphoma after a 10-year history of ankylosing spondylitis. The clinical disease manifested as a unilateral, solitary adrenal tumor, fever and body weight loss. The fever subsided after surgical removal of the adrenal tumor. Systemic chemotherapy was administered postoperatively. The patient was leading an uneventful life 44 months after the initial diagnosis. To our knowledge, this is the first case of angiotropic lymphoma associated with ankylosing spondylitis. It is also the second reported case manifesting with a unilateral solitary adrenal tumor without systemic involvement.
authors.affiliation: Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
authors.forename: J P
authors.initials: JP
authors.lastname: Gau
authors.forename: C F
authors.initials: CF
authors.lastname: Chiu
authors.forename: S M
authors.initials: SM
authors.lastname: Liu
authors.forename: H C
authors.initials: HC
authors.lastname: Hsu
authors.forename: C H
authors.initials: CH
authors.lastname: Ho
authors.forename: W K
authors.initials: WK
authors.lastname: Chau
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000209:etiology*; D000368:Aged; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications*; D008297:Male; D013167:Spondylitis, Ankylosing / Q000150:complications*