title: Melanoma lymphoscintigraphy and lymphatic mapping.
abstract: Lymphoscintigraphy in melanoma has proven to be a reliable method to identify regional lymph nodes at risk for metastases. The first lymph node to drain a cutaneous lesion, the sentinel lymph node (SLN), is predictive of the metastatic status of the regional lymph node group. Lymphatic mapping allows for the identification of the SLN and for selective lymph node sampling. Selective lymph node sampling is less invasive and because only a small quantity of high-risk tissue is submitted for pathological examination, it allows for a more complete and comprehensive pathological examination, which identifies melanoma with up to 100 times the sensitivity of conventional examinations.
authors.affiliation: H. Lee Moffitt Cancer Center, Department of Radiology, Tampa, FL 33612, USA.
authors.forename: C G
authors.initials: CG
authors.lastname: Berman
authors.forename: J
authors.initials: J
authors.lastname: Choi
authors.forename: M R
authors.initials: MR
authors.lastname: Hersh
authors.forename: R A
authors.initials: RA
authors.lastname: Clark
mesh_terms: D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging*; D008545:Melanoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D009367:Neoplasm Staging; D016719:Radioimmunodetection