Blood pressure exceeding national guidelines among women after stroke.
OBJECTIVE
After a transient ischemic attack or stroke, the risk for recurrence may be reduced by treatment of hypertension. The purpose of this study was to determine how commonly blood pressure exceeds national guidelines among patients who have had one of these events.


METHODS
Subjects were 644 women participating in a randomized trial of estrogen for secondary stroke prevention. We measured blood pressure 1 month after the stroke or TIA while patients were under the care of their personal physicians. Among 536 patients, a second measure was made at an average of 2.9 years after the first.


RESULTS
The mean age of participants was 71 years, and 73% reported a history of hypertension. At baseline, only 44% (280/644) of the women had blood pressure values within national guidelines (<140/90 mm Hg). With separate guidelines used for diabetics (<130/85 mm Hg) and nondiabetics (<140/90 mm Hg), the proportions of women within the guidelines were 27% and 44%, respectively. Overall, 39% of patients were within the diabetes-adjusted guidelines. Among patients whose blood pressure exceeded 140/90 mm Hg at first examination, 55% were still in excess at follow-up. Features associated with severe hypertension at first examination (>160/100 mm Hg) were history of hypertension, education less than college, and higher cognitive functioning.


CONCLUSIONS
Blood pressure values in excess of national guidelines are common after stroke and TIA, especially among diabetic patients. Efforts to lower blood pressure control may enhance secondary prevention.
Kernan
W N
WN
Departments of Internal Medicine, Yale University School of Medicine, New Haven, CT 06504, USA. walter.kernan@yale.edu
Viscoli
C M
CM
Brass
L M
LM
Makuch
R W
RW
Sarrel
P M
PM
Horwitz
R I
RI
D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000592:standards; D004967:Estrogens / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000503:physiopathology*; D008875:Middle Aged; D017410:Practice Guidelines as Topic / Q000592:standards; D012307:Risk Factors; D020521:Stroke / Q000503:physiopathology* / Q000517:prevention & control*
D004967:Estrogens