title: Treatment of furcation defects with DFDBA combined with GTR: human histologic evaluation of a case.
abstract: The purpose of this study was to evaluate whether regeneration is possible in human furcation defects. Three molars with Class II furcation involvement were included in this study. A notch was placed in calculus in the furcation to serve as a reference point for histologic evaluation. The defects were treated with a demineralized freeze-dried bone allograft combined with a bioabsorbable membrane. At 6 months postoperative, the teeth were extracted with a small piece of tissue from the furcation area. The samples were then processed for histologic evaluation. Regeneration was found in 2 of the 3 samples. This study demonstrated that regeneration is possible in human furcation defects.
authors.forename: R J
authors.initials: RJ
authors.lastname: Harris
mesh_terms: D020341:Absorbable Implants; D001861:Bone Regeneration; D016025:Bone Transplantation / Q000379:methods*; D002951:Citrates; D005260:Female; D005612:Freeze Drying; D017823:Furcation Defects / Q000601:surgery*; D006801:Humans; D008334:Mandible; D008567:Membranes, Artificial; D008875:Middle Aged; D008963:Molar; D011091:Polyesters
chemical_list: D002951:Citrates; C105021:Guidor; D008567:Membranes, Artificial; D011091:Polyesters