title: Spectral coherence between blood pressure and inter-beat intervals in hypertension.
abstract: Continuous registration of blood pressure (BP) was obtained in 31 normotensives and 76 hypertensives (divided into 3 stages of hypertension) by a method where the blood pressure in a human finger was measured non-invasively in a beat-by-beat fully calibrated manner. From this signal, the power density spectra of inter-beat intervals (IBI), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were derived. Total spectral power (TP) and low/high spectral frequency ratios of all spectra were calculated. Cross-correlation analysis between IBI, SBP and DBP spectra showed that the level of amplitude and phase spectral coherence (SC) was strongly dependent of the stage of hypertension. SC was calculated by means of appropriate mathematical algorithms. Multiple step regression analysis pointed out that the observed phenomenon is highly significant for both--the amplitude and the phase SC (p < 0.01).
authors.affiliation: National Centre of Hygiene, Medical Ecology and Nutrition, Sofia, Bulgaria. Danev@NCH.Aster.Net
authors.forename: S
authors.initials: S
authors.lastname: Danev
authors.forename: E
authors.initials: E
authors.lastname: Datzov
authors.forename: S
authors.initials: S
authors.lastname: Svetoslavov
authors.forename: D
authors.initials: D
authors.lastname: Mikhov
authors.forename: P
authors.initials: P
authors.lastname: Markova
authors.forename: R
authors.initials: R
authors.lastname: Girchev
mesh_terms: D000328:Adult; D001794:Blood Pressure; D016022:Case-Control Studies; D005583:Fourier Analysis; D006329:Heart Conduction System; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D016014:Linear Models; D008875:Middle Aged; D008955:Models, Cardiovascular