title: Whole body air displacement plethysmography compared with hydrodensitometry for body composition analysis.
abstract: OBJECTIVE
  To assess the acceptability and feasibility of whole body air displacement plethysmography in children and to determine its precision and agreement with hydrodensitometry, an appropriate reference method.
  
  
  METHODS
  Age specific two component model equations were used to predict fat mass from body density in 22 children aged 8-12 years and in 10 adults for comparison of methods. Precision for each method was established from duplicate measurements.
  
  
  RESULTS
  Plethysmography was accepted more readily than hydrodensitometry (100% v 69% provided duplicate measurements). Precision for fat mass in children was 0.38 kg by plethysmography and 0.68 kg by hydrodensitometry, and results were similar in adults. The mean (SD) fat mass in children was 6.9 kg (4.0) and 6.7 kg (4. 2) by plethysmography and hydrodensitometry, respectively, but 95% limits of agreement between methods were large (-4.1 kg to 3.5 kg fat).
  
  
  CONCLUSIONS
  Plethysmography was more readily accepted and had better precision than hydrodensitometry. It also provided similar body composition results for the group but not for all individual children.
authors.affiliation: Clinical Pharmacology Department, SmithKline Beecham Pharmaceuticals, New Frontiers Science Park (South), Third Avenue, Harlow CM19 5AW, UK.
authors.forename: O
authors.initials: O
authors.lastname: Dewit
authors.forename: N J
authors.initials: NJ
authors.lastname: Fuller
authors.forename: M S
authors.initials: MS
authors.lastname: Fewtrell
authors.forename: M
authors.initials: M
authors.lastname: Elia
authors.forename: J C
authors.initials: JC
authors.lastname: Wells
mesh_terms: D000273:Adipose Tissue / Q000033:anatomy & histology; D000293:Adolescent; D000328:Adult; D001823:Body Composition; D002648:Child; D002675:Child, Preschool; D003720:Densitometry; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D010993:Plethysmography, Whole Body / Q000379:methods*; D015203:Reproducibility of Results