Antagonistic interaction between the convulsant activities of pefloxacin and its main metabolite norfloxacin in rats.
Delon
A
A
UPRES EA 1223, Faculté de Médecine & Pharmacie, Poitiers, France.
Levasseur
L M
LM
Giraudon
M
M
Bouquet
S
S
Couet
W
W
D000465:Algorithms; D000818:Animals; D000890:Anti-Infective Agents / Q000037:antagonists & inhibitors* / Q000633:toxicity*; D003292:Convulsants / Q000633:toxicity*; D004347:Drug Interactions; D008297:Male; D008954:Models, Biological; D009643:Norfloxacin / Q000037:antagonists & inhibitors* / Q000493:pharmacokinetics / Q000633:toxicity*; D015366:Pefloxacin / Q000037:antagonists & inhibitors* / Q000493:pharmacokinetics / Q000633:toxicity*; D051381:Rats; D017207:Rats, Sprague-Dawley
D000890:Anti-Infective Agents; D003292:Convulsants; D015366:Pefloxacin; D009643:Norfloxacin