title: [Prognostic markers for prostate cancer].
abstract: Careful consideration of therapy for prostate cancer needs an accurate analysis of prognostic markers to estimate success and benefit for the patient. Prognosis of prostate cancer is determined by the proportion of high grade cancer, many usually utilized prognostic characteristics were rejected by multivariate analysis as no independent prognostic information was delivered. For planning therapy it is crucial to estimate the proportion of high grade cancer as exact as possible. A standardized biopsy technique combined with a quantified analysis of the biopsy cores is most helpful to achieve this goal. The prognostic value of molecular biological and other factors is object of research, only a combination of some of these factors could be demonstrated so far to be superior to the estimation of the proportion of high grade cancer. However, at present their routine use in daily practise is precluded by a high technical and financial expense.
authors.affiliation: Urologische Klinik, Universitätskrankenhaus Eppendorf, Hamburg.
authors.forename: M
authors.initials: M
authors.lastname: Graefen
authors.forename: P
authors.initials: P
authors.lastname: Hammerer
authors.forename: J
authors.initials: J
authors.lastname: Noldus
authors.forename: A
authors.initials: A
authors.lastname: Haese
authors.forename: U
authors.initials: U
authors.lastname: Pichelmeier
authors.forename: A
authors.initials: A
authors.lastname: Erbersdobler
authors.forename: H
authors.initials: H
authors.lastname: Henke
authors.forename: S
authors.initials: S
authors.lastname: Conrad
authors.forename: S
authors.initials: S
authors.lastname: Fernandez
authors.forename: H
authors.initials: H
authors.lastname: Huland
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood; D001706:Biopsy; D006801:Humans; D008297:Male; D011379:Prognosis; D011467:Prostate / Q000473:pathology; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy
chemical_list: D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen