[Event-related potential (P300) in two epileptic cases with continuous spike-waves during slow wave sleep].
We studied the P300 of two epileptic cases with almost continuous diffuse spike-wave discharges on sleep EEG: one with epilepsy with continuous spike-waves during slow wave sleep, and another with atypical benign partial epilepsy. These cases showed a marked prolongation of P300 latencies during nonconvulsive status epilepticus with continuous spike-waves during slow wave sleep. As they improved clinically and electroencephalographically, the latencies became normal. These findings indicate that P300 is a useful method to elucidate the pathophysiology of nonconvulsive status epilepticus with continuous spike-waves during slow wave sleep.
Kohno
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Department of Pediatrics, Hamamatsu Seirei General Hospital, Shizuoka.
D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D004569:Electroencephalography; D004827:Epilepsy / Q000188:drug therapy / Q000503:physiopathology*; D018913:Event-Related Potentials, P300; D005260:Female; D006801:Humans; D008297:Male; D011930:Reaction Time; D012890:Sleep / Q000502:physiology*
D000927:Anticonvulsants