title: Epidemic typhoid in vietnam: molecular typing of multiple-antibiotic-resistant Salmonella enterica serotype typhi from four outbreaks.
abstract: Multidrug-resistant Salmonella enterica serotype Typhi isolates from four outbreaks of typhoid fever in southern Vietnam between 1993 and 1997 were compared. Pulsed-field gel electrophoresis, bacteriophage and plasmid typing, and antibiotic susceptibilities showed that independent outbreaks of multidrug-resistant typhoid fever in southern Vietnam are caused by single bacterial strains. However, different outbreaks do not derive from the clonal expansion of a single multidrug-resistant serotype Typhi strain.
authors.affiliation: The Department of Biochemistry, Imperial College of Science, Technology and Medicine, London SW7 2AZ, United Kingdom.
authors.forename: P
authors.initials: P
authors.lastname: Connerton
authors.forename: J
authors.initials: J
authors.lastname: Wain
authors.forename: T T
authors.initials: TT
authors.lastname: Hien
authors.forename: T
authors.initials: T
authors.lastname: Ali
authors.forename: C
authors.initials: C
authors.lastname: Parry
authors.forename: N T
authors.initials: NT
authors.lastname: Chinh
authors.forename: H
authors.initials: H
authors.lastname: Vinh
authors.forename: V A
authors.initials: VA
authors.lastname: Ho
authors.forename: T S
authors.initials: TS
authors.lastname: Diep
authors.forename: N P
authors.initials: NP
authors.lastname: Day
authors.forename: N J
authors.initials: NJ
authors.lastname: White
authors.forename: G
authors.initials: G
authors.lastname: Dougan
authors.forename: J J
authors.initials: JJ
authors.lastname: Farrar
mesh_terms: D015373:Bacterial Typing Techniques; D004196:Disease Outbreaks; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D012485:Salmonella typhi / Q000145:classification / Q000187:drug effects / Q000235:genetics; D014435:Typhoid Fever / Q000453:epidemiology* / Q000382:microbiology*; D014744:Vietnam / Q000453:epidemiology