Brown tumour as a complication of secondary hyperparathyroidism in severe long-lasting vitamin D deficiency rickets.
Brown tumour is a localised form of fibrous-cystic osteitis associated with primary or secondary hyperparathyroidism. Despite the fact that secondary hyperparathyroidism occurs in vitamin D deficiency rickets, no cases of rickets with brown tumour have so far been described. We present a 2.9-year-old girl who had brown tumour of the mandible due to severe vitamin D deficiency rickets. Treatment with vitamin D3 corrected the hyperparathyroidism rapidly which was followed by gradual regression in tumour size.


CONCLUSIONS
Brown tumour can develop in severe, long-standing vitamin D deficiency rickets and responds to vitamin D treatment.
Bereket
A
A
Department of Paediatrics, Hacettepe University, Ihsan Dogramaci Children's Hospital, Ankara, Turkey.
Casur
Y
Y
Firat
P
P
Yordam
N
N
D002675:Child, Preschool; D002762:Cholecalciferol / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D007015:Hypophosphatemia, Familial / Q000097:blood / Q000150:complications*; D008336:Mandibular Diseases / Q000209:etiology*; D010002:Osteitis Fibrosa Cystica / Q000209:etiology*
D002762:Cholecalciferol