New carbazole alkaloids from Clausena anisata with antitumor promoting activity.
Four new carbazole alkaloids, named clausamine D (1), E (2), F (3), and G (4), were isolated from Clausena anisata as inhibitors of Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoylphorbol-13-acetate in Raji cells.
Ito
C
C
Faculty of Pharmacy, Meijo University, Tempaku, Nagoya 468-8503, Japan.
Katsuno
S
S
Itoigawa
M
M
Ruangrungsi
N
N
Mukainaka
T
T
Okuda
M
M
Kitagawa
Y
Y
Tokuda
H
H
Nishino
H
H
Furukawa
H
H
D000956:Antigens, Viral / Q000187:drug effects; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002227:Carbazoles / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D010944:Plants / Q000737:chemistry*; D013057:Spectrum Analysis
D000956:Antigens, Viral; D000972:Antineoplastic Agents, Phytogenic; D002227:Carbazoles; C033305:Epstein-Barr virus early antigen