An aggressive intrasinusoidal lymphoma presenting with marked systemic disturbance but normal imaging studies.
A patient with an aggressive intrasinusoidal non-Hodgkins lymphoma, presenting with marked systemic disturbance but only a mildly raised alkaline phosphatase as a localising sign is described. All imaging studies of the liver were normal and the diagnosis was delayed until a percutaneous liver biopsy was performed. Once diagnosed, the patient responded extremely well to conventional anti-lymphoma chemotherapy.
Camidge
R
R
Newcastle General Hospital, Newcastle upon Tyne NE4 6BE, UK.
Ong
E
E
Lucraft
H
H
D005188:False Negative Reactions; D005335:Fever of Unknown Origin / Q000209:etiology*; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications* / Q000175:diagnosis; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged