Small-bowel angiosarcoma after pelvic irradiation: a report of two cases.
Angiosarcoma is a rare tumor in the small bowel. Several predisposing factors have been suggested, including external irradiation for another malignancy. Only six cases of small-bowel angiosarcoma in patients previously treated with pelvic irradiation for gynecological malignancies have been reported hitherto. We present here two patients in whom a diagnosis of small-bowel angiosarcoma was made 10 years or more after intrapelvic irradiation. These cases demonstrate poor prognosis in this disease. Although postirradiation angiosarcoma is a rare condition, its possibility should be kept in mind when operating on previously irradiated patients.
Aitola
P
P
Departments of Surgery and Pathology, Tampere University Hospital and Medical School, University of Tampere, P.O. Box 2000, FIN-33521 Tampere, Finland. petri.aitola@pp.fimnet.fi
Poutiainen
A
A
Nordback
I
I
D000230:Adenocarcinoma / Q000532:radiotherapy* / Q000601:surgery; D000368:Aged; D003131:Combined Modality Therapy; D016889:Endometrial Neoplasms / Q000532:radiotherapy / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006394:Hemangiosarcoma / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007078:Ileal Neoplasms / Q000175:diagnosis* / Q000628:therapy; D007580:Jejunal Neoplasms / Q000175:diagnosis* / Q000628:therapy; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis* / Q000628:therapy; D010388:Pelvis / Q000528:radiation effects*; D014594:Uterine Neoplasms / Q000532:radiotherapy* / Q000601:surgery