title: Segmental hepatic vein thrombosis associated with heparin-induced thrombocytopenia II.
abstract: We report the case of a 55-year-old man who developed heparin-induced thrombocytopenia II after a vertebral fracture. Autopsy revealed segmental hepatic vein thrombosis of the right lobe with subacute congestion and an activation of hepatic stellate cells. This case shows that heparin-induced thrombocytopenia II is a possible cause of the Budd-Chiari syndrome.
authors.affiliation: Department of Pathology, University of Bonn, Post Box 2120, D-53011 Bonn, Germany. theuerk@mailer.meb.uni-bonn.de
authors.forename: I
authors.initials: I
authors.lastname: Theuerkauf
authors.forename: L
authors.initials: L
authors.lastname: Lickfett
authors.forename: U
authors.initials: U
authors.lastname: Harbrecht
authors.forename: C
authors.initials: C
authors.lastname: Pohl
authors.forename: H
authors.initials: H
authors.lastname: Fischer
authors.forename: U
authors.initials: U
authors.lastname: Pfeifer
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects*; D015415:Biomarkers / Q000032:analysis; D006502:Budd-Chiari Syndrome / Q000209:etiology* / Q000473:pathology; D006493:Heparin / Q000009:adverse effects*; D006503:Hepatic Veins / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008099:Liver / Q000098:blood supply / Q000737:chemistry / Q000187:drug effects / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013921:Thrombocytopenia / Q000139:chemically induced*
chemical_list: D000925:Anticoagulants; D015415:Biomarkers; D006493:Heparin