title: [Sepsis and antibiotic prophylaxis in stereotaxic neurosurgery].
abstract: BACKGROUND
  Stereotaxic surgery is becoming increasingly important because of the possibility of approaching the deep zones of the brain with less risk. It is in daily use in cerebral tumours and in the functional surgery of Parkinson's disease. The use of antibiotic prophylaxis in neurosurgery is controversial, although in many centres, including ours, all patients receive it.
  
  
  OBJECTIVE
  To study the pre-operative clinical characteristics analysing the antibiotic prophylaxis used, septic complications seen and their management.
  
  
  METHODS
  In this study we included 93 patients with neurosurgical disorders operated on using a stereotaxic approach in the Neurosurgical Department of the Centro Internacional de Restauración Neurologica (Cuba) during 1997 and 1998, in which antibiotic prophylaxis was used and septic patients detected. The variables studied included age, sex, neurological disorders, surgical operations done and the antibiotic used for prophylaxis. We analysed the test of clinical criteria for sepsis in all patients.
  
  
  RESULTS
  We found that a greater number of patients operated on had had functional surgery, which showed its importance as an alternative surgical method in Parkinson's disease. There was satisfactory use of antibiotic prophylaxis with a reduction in the rate of nosocomial infection; most infections were seen in the lower respiratory tract.
  
  
  CONCLUSIONS
  These results support the hypothesis of use of antibiotic prophylaxis in stereotaxic surgery to achieve a reduction in intra-hospital infections in surgical patients.
authors.affiliation: Servicio de Neurocirugía, Centro Internacional de Restauración Neurológica (CIREN), La Habana, Cuba. bvidalm@infomed.sld.cu
authors.forename: A
authors.initials: A
authors.lastname: Padrón-Sánchez
authors.forename: L
authors.initials: L
authors.lastname: Ochoa-Zaldivar
authors.forename: G
authors.initials: G
authors.lastname: López-Flores
authors.forename: I
authors.initials: I
authors.lastname: García-Maeso
authors.forename: J A
authors.initials: JA
authors.lastname: Barnés-Domínguez
authors.forename: D
authors.initials: D
authors.lastname: Reconde-Suárez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019072:Antibiotic Prophylaxis / Q000379:methods*; D001921:Brain / Q000601:surgery*; D001932:Brain Neoplasms / Q000601:surgery*; D002391:Catchment Area, Health; D003428:Cross Infection / Q000382:microbiology / Q000517:prevention & control; D004927:Escherichia coli Infections / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods; D010300:Parkinson Disease / Q000601:surgery; D011300:Preoperative Care; D011512:Proteus Infections / Q000150:complications; D012189:Retrospective Studies; D018805:Sepsis / Q000453:epidemiology / Q000517:prevention & control*; D013238:Stereotaxic Techniques