The awesome power of yeast biochemical genomics.
A new genomic strategy for identifying the gene encoding any biochemical activity has recently been developed, in which an array of individual yeast strains expressing a genomic set of open reading frames fused to glutathione S-transferase can be assayed for a biochemical activity of interest. Designated 'biochemical genomics', this approach represents an innovative application of genomic information.
Carlson
M
M
Department of Genetics and Development, Columbia University, 701 W. 168th St, HSC922, New York, NY 10032, USA. mbc1@columbia.edu
D005800:Genes, Fungal; D005821:Genetic Techniques; D005982:Glutathione Transferase / Q000378:metabolism*; D008967:Molecular Biology / Q000379:methods*; D016366:Open Reading Frames; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics
D011993:Recombinant Fusion Proteins; D005982:Glutathione Transferase