Nodular regenerative hyperplasia of the liver: case report of a 13-year-old girl and review of the literature.
BACKGROUND
Nodular regenerative hyperplasia (NRH) of the liver is a multi-acinar regenerative nodular lesion in a non-cirrhotic liver. It is a rare entity, especially in children, and remains of unknown aetiology.


OBJECTIVE
NRH is often seen in association with other diseases or drug intake. In half of patients it is complicated by portal hypertension. Radiologically, its nodular appearance may look like neoplasia.


RESULTS
We report a case of NRH with enormous hepatomegaly and multiple huge nodules.


CONCLUSIONS
We wish to emphasise the importance of open wedge biopsy to establish diagnosis, since the prognosis of NRH in the absence of portal hypertension is good. Complications such as rupture of a nodule are rare.
Trenschel
G M
GM
Department of Diagnostic Radiology, Paediatric Radiology, University of Cologne Medical School, Kerpener Strasse 68, D-50924 Cologne, Germany.
Schubert
A
A
Dries
V
V
Benz-Bohm
G
G
D000293:Adolescent; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000175:diagnosis* / Q000473:pathology; D011379:Prognosis; D014057:Tomography, X-Ray Computed