title: Adaptation to a standardized training program and changes in fitness in a large, heterogeneous population: the HERITAGE Family Study.
abstract: OBJECTIVE
  This paper describes the variations in response to a standardized, computer-controlled training program.
  
  
  METHODS
  Steady-state heart rate (HR) and oxygen intake (VO2) of 614 healthy, sedentary men and women aged 16-65 yr were measured during three cycle ergometer exercise tests. The HR associated with 55, 65, 70, and 75% of each subject's pretraining VO2max was used to prescribe exercise intensity. Subjects exercised three times a week, beginning at a HR associated with 55% VO2max for 30 min. Duration and intensity was gradually increased over 20 wk of training. The duration and HR of each training session were controlled by a computer.
  
  
  RESULTS
  Using the linear relationship between HR, VO2 and power output (PO), PO were predicted for each of 60 training sessions at the respective programmed HR. The average ratio of the actual training HR to programmed HR was 0.99. It was hypothesized that participants whose actual training PO exceeded their predicted PO would improve VO2max more than those whose actual PO was less than their predicted PO. Using the ratio of actual/predicted PO determined after the training was over, participants were arbitrarily assigned to three groups: 128 participants had low (LO) ratios (0.65-0.84), 408 had average (AV) ratios (0.85-1.14), and 78 had high (HI) ratios (1.15-1.34). Secondary analysis showed that the training program significantly increased mean VO2max of all three groups. Those who had a smaller increase in training PO (LO) had significantly less increase in VO2max than those with larger increases in PO (HI).
  
  
  CONCLUSIONS
  People who exercise at a HR associated with the same %VO2max can vary substantially in their training PO, in their rate of increase in PO over a 20-wk training program, and in improvement of their VO2max.
authors.affiliation: Indiana University, Bloomington, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Skinner
authors.forename: K M
authors.initials: KM
authors.lastname: Wilmore
authors.forename: J B
authors.initials: JB
authors.lastname: Krasnoff
authors.forename: A
authors.initials: A
authors.lastname: Jaskólski
authors.forename: A
authors.initials: A
authors.lastname: Jaskólska
authors.forename: J
authors.initials: J
authors.lastname: Gagnon
authors.forename: M A
authors.initials: MA
authors.lastname: Province
authors.forename: A S
authors.initials: AS
authors.lastname: Leon
authors.forename: D C
authors.initials: DC
authors.lastname: Rao
authors.forename: J H
authors.initials: JH
authors.lastname: Wilmore
authors.forename: C
authors.initials: C
authors.lastname: Bouchard
mesh_terms: D000222:Adaptation, Physiological; D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D003201:Computers; D016552:Ergometry; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005192:Family Health; D005260:Female; D005544:Forecasting; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology; D010806:Physical Education and Training; D010809:Physical Fitness / Q000502:physiology*