[Chemically-induced paraneoplastic hyperleukocytic lung].
Dyspnea is the principal clinical feature of pulmonary leukostasis, a syndrome called "poumon hyperleucocytaire" in French. It is a common complication of chronic myeloid leukemia. In the course of pulmonary carcinoma, leukocytosis is frequently noted. One of the etiologies is a paraneoplastic syndrome with production of colony stimulating factor. We report a case of pulmonary hyperleukostasis following antineoplastic chemotherapy for pulmonary carcinoma.
Le Guen
Y
Y
Service de Pneumologie, Hôpital Saint-Antoine, Paris.
Lebeau
B
B
D000208:Acute Disease; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects; D001706:Biopsy; D001999:Bronchoscopy; D016190:Carboplatin / Q000009:adverse effects; D002283:Carcinoma, Bronchogenic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005047:Etoposide / Q000009:adverse effects; D006801:Humans; D007955:Leukemoid Reaction / Q000175:diagnosis*; D007958:Leukocyte Count; D018921:Leukostasis / Q000139:chemically induced* / Q000175:diagnosis / Q000000981:diagnostic imaging; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000000981:diagnostic imaging; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D010257:Paraneoplastic Syndromes / Q000175:diagnosis; D013902:Radiography, Thoracic; D012131:Respiratory Insufficiency / Q000209:etiology
D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D005047:Etoposide; D016190:Carboplatin