Segmental hepatic vein thrombosis associated with heparin-induced thrombocytopenia II.
We report the case of a 55-year-old man who developed heparin-induced thrombocytopenia II after a vertebral fracture. Autopsy revealed segmental hepatic vein thrombosis of the right lobe with subacute congestion and an activation of hepatic stellate cells. This case shows that heparin-induced thrombocytopenia II is a possible cause of the Budd-Chiari syndrome.
Theuerkauf
I
I
Department of Pathology, University of Bonn, Post Box 2120, D-53011 Bonn, Germany. theuerk@mailer.meb.uni-bonn.de
Lickfett
L
L
Harbrecht
U
U
Pohl
C
C
Fischer
H
H
Pfeifer
U
U
D000925:Anticoagulants / Q000009:adverse effects*; D015415:Biomarkers / Q000032:analysis; D006502:Budd-Chiari Syndrome / Q000209:etiology* / Q000473:pathology; D006493:Heparin / Q000009:adverse effects*; D006503:Hepatic Veins / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008099:Liver / Q000098:blood supply / Q000737:chemistry / Q000187:drug effects / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013921:Thrombocytopenia / Q000139:chemically induced*
D000925:Anticoagulants; D015415:Biomarkers; D006493:Heparin