[Parry-Romberg progressive facial hemiatrophy: pathogenic and evolutionary considerations with regards to a case followed up for a long period of time].
BACKGROUND
The Parry-Romberg syndrome is a clinical condition in which there is progressive facial hemiatrophy which may be associated with neurological, ocular, cutaneous and auto-immune disorders. It is of unknown aetiology, although many theories have been put forward.


METHODS
We present a case of left facial hemiatrophy associated with ipsilateral lingual hemiatrophy and signs of cortico-cerebellar dysfunction, the neuroimaging findings (NMR) and clinico-radiological follow-up covered a period of over 10 years.


CONCLUSIONS
The data on the clinical course and neuroimaging, together with our review of the literature, suggest that the Parry-Romberg syndrome may be considered to be a dysgenetic process which may originate during the first stages of CNS embryogenesis.
Olivares-Romero
J
J
Sección de Neurología, Hospital Torrecárdenas, Almería, España. med000185@nacom.es
Casado-Torres
A
A
Serrano-Castro
P J
PJ
Guardado-Santervás
P
P
Peralta-Labrador
J I
JI
Goberna-Ortiz
E
E
D001284:Atrophy / Q000473:pathology; D001921:Brain / Q000473:pathology*; D002531:Cerebellum / Q000473:pathology / Q000503:physiopathology; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology; D018450:Disease Progression; D004569:Electroencephalography; D005150:Facial Hemiatrophy / Q000175:diagnosis*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013997:Time Factors; D014060:Tongue Diseases / Q000473:pathology