[An experimental validation of pharmacological agents to arrest the vestibulo-autonomic syndrome (motion sickness)].
The results of development and experimental evaluation of the efficiency of pharmacological means of cupping the vestibulo-vegetative syndrome in man are presented. A model and procedure of evaluation of pharmacological cupping of the Vestibulo-vegetative syndrome are developed. The intramuscular injection of the mixture containing ephedrine, promethazine hydrochloride and strychnine (25, 50, and 1 mg, respectively) appeared most effective.
Shashkov
V S
VS
N. A. Semashko Moscow Medical Stomatologic Institute, Russia.
Kotovskaia
A R
AR
Orlov
O I
OI
Koloteva
M I
MI
Shashkov
A V
AV
Karsanova
S K
SK
D003312:Coriolis Force; D004359:Drug Therapy, Combination; D004809:Ephedrine / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D009041:Motion Sickness / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control* / Q000523:psychology; D011398:Promethazine / Q000008:administration & dosage / Q000009:adverse effects; D013331:Strychnine / Q000008:administration & dosage / Q000009:adverse effects; D013577:Syndrome; D013997:Time Factors; D014724:Vestibular Function Tests / Q000706:statistics & numerical data
D011398:Promethazine; D004809:Ephedrine; D013331:Strychnine