Reactions to corticosteroids: some new aspects regarding cross-sensitivity.
Patch test results obtained with corticosteroid allergic patients tested with a large corticosteroid series validated the earlier classification of corticosteroid molecules in four groups of cross-reacting molecules: i.e., group A (hydrocortisone type), group B (acetonides), group C (betamethasone type-non esterified) and group D (esters). The latter group can now be subclassified into 2 groups, i.e., group D1 (halogenated and with C16 substitution) and group D2 (the "labile" prodrug esters without the latter characteristics).
Goossens
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A
Department of Dermatology, Leuven University Hospital, Katholieke Universiteit Leuven, Belgium.
Matura
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M
Degreef
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H
D000305:Adrenal Cortex Hormones / Q000009:adverse effects* / Q000145:classification*; D003429:Cross Reactions; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D010328:Patch Tests
D000305:Adrenal Cortex Hormones