title: Haemophilic; arthropathy: assessment of quality of life after total knee arthroplasty.
abstract: The goal of this study was to examine how the known effects of total knee arthroplasty (TKA) on clinical outcome parameters translate into improved quality of life, as measured with validated condition-specific and generic questionnaires (Knee Society Score, WOMAC, SF-12, transition questions), addressing physical, mental and social health. Eleven patients (13 knees) undergoing TKA from 1986 to 1994, with the diagnosis of severe haemophilic arthropathy of the knee, were followed-up over a 4-year period on average. TKA was found to reduce the burden of disease to levels similar to patients with osteoarthritis undergoing hip arthroplasty. Clinical and functional improvement after TKA translated into a substantial and significant increase in quality of life and patient satisfaction, found in objective as well as in patient-perceived measures. However, the physical functional ability did not reach the same level as in the corresponding population not affected by haemophilia, due to residual symptoms and impairment of other joints.
authors.affiliation: Department of Rheumatology and Physical Medicine, University Hospital Zurich, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: Schick
authors.forename: G
authors.initials: G
authors.lastname: Stucki
authors.forename: M
authors.initials: M
authors.lastname: Rodriguez
authors.forename: E O
authors.initials: EO
authors.lastname: Meili
authors.forename: E
authors.initials: E
authors.lastname: Huber
authors.forename: B A
authors.initials: BA
authors.lastname: Michel
authors.forename: P
authors.initials: P
authors.lastname: Brühlmann
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D019645:Arthroplasty, Replacement, Knee; D015331:Cohort Studies; D006305:Health Status Indicators; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D011788:Quality of Life; D016059:Range of Motion, Articular; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome