[Effectiveness of enalapril in chronic cor pulmonale].
The aim of our investigation was assessment of enalapril effects in cor pulmonale. 20 patients with chronic obstructive pulmonary diseases complicate with cor pulmonale received combined treatment including enalapril. The course of such treatment led to a significant lowering of systolic and diastolic pressure in the pulmonary artery, systemic arterial pressure, specific peripheral resistance and minute volume in patients with hyperkinetic and mixed types of hemodynamics. Parameters of ECG and exercise tolerance improved. Enalapril is effective in correction of pulmonary and central hemocirculation in chronic cor pulmonale.
Vasilenko
G P
GP
Vereshchagina
G N
GN
Dolganova
D N
DN
Morzhueva
N M
NM
Popova
S S
SS
D000328:Adult; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D002908:Chronic Disease; D004656:Enalapril / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011660:Pulmonary Heart Disease / Q000188:drug therapy*
D000806:Angiotensin-Converting Enzyme Inhibitors; D004656:Enalapril