Transcutaneous oxygen tension in subjects with tetraplegia with and without pressure ulcers: a preliminary report.
This study compared transcutaneous oxygen tension (TcpO2) in subjects with paraplegia and pressure ulcers (PU), those with paraplegia and no pressure ulcer (NPU), and ambulatory controls. TcpO2 was measured using a surface-electrode monitoring system, recorded at 1-min intervals for 5 min and averaged. Mean TcpO2 was significantly lower in the PU than the NPU and control groups (23.53+/-1.83 vs. 58.93+/-2.53 and 79.70+/-6.77 mmHg, respectively, p<0.05). In a PU subgroup (n=4) mean TcpO2 of the pressure ulcer and nonpressure ulcer sides (trochanter or ischium) were significantly different (21.05+/-2.98 vs. 67.65+/-2.11 mmHg, respectively, p<0.001). Additionally, the NPU group demonstrated significantly lower TcpO2 than the controls. PUs had a greater reduction in TcpO2 levels relative to controls than NPUs. No association was found between TcpO2 and duration of injury, completeness of lesion, or smoking history. Thus, TcpO2 may be an effective method to identify individuals who are susceptible to pressure ulcers. The further attenuation of TcpO2 observed in the PU group may be useful to help predict whether ulcers will heal with local care or will require additional treatment.
Liu
M H
MH
Spinal Cord Damage Research Center and Department of Vascular Surgery, Veterans Affairs Medical Center, Bronx, NY 10468, USA.
Grimm
D R
DR
Teodorescu
V
V
Kronowitz
S J
SJ
Bauman
W A
WA
D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D015415:Biomarkers; D001785:Blood Gas Monitoring, Transcutaneous / Q000295:instrumentation / Q000379:methods*; D001830:Body Surface Area; D016022:Case-Control Studies; D004198:Disease Susceptibility; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*; D011237:Predictive Value of Tests; D003668:Pressure Ulcer / Q000209:etiology*; D011782:Quadriplegia / Q000150:complications* / Q000378:metabolism*; D015203:Reproducibility of Results; D013997:Time Factors; D014945:Wound Healing
D015415:Biomarkers; D010100:Oxygen