title: A novel polymorphism in the human interleukin-13 (IL-13) promoter.
abstract: Using PCR-SSCP and automated nucleotide sequencing we have identified a novel single nucleotide C --> T polymorphism in the human IL-13 promoter, at position -1055 relative to the transcription start site. Allele frequency analysis in a population of normal cord blood donors indicated frequencies of 0.833 (C) and 0. 167 (T).
authors.affiliation: Division of Transplantation Sciences, University of Bristol, UK.
authors.forename: G J
authors.initials: GJ
authors.lastname: Laundy
authors.forename: C F
authors.initials: CF
authors.lastname: Spink
authors.forename: L J
authors.initials: LJ
authors.lastname: Keen
authors.forename: N A
authors.initials: NA
authors.lastname: Wood
authors.forename: J L
authors.initials: JL
authors.lastname: Bidwell
mesh_terms: D001483:Base Sequence; D006801:Humans; D018793:Interleukin-13 / Q000235:genetics*; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D018807:Polymorphism, Single-Stranded Conformational; D011401:Promoter Regions, Genetic; D012689:Sequence Homology, Nucleic Acid
chemical_list: D018793:Interleukin-13