title: Megistosarcimine and megistosarconine, two alkaloids from Sarcomelicope megistophylla.
abstract: Two new alkaloids, megistosarcimine and megistosarconine, were isolated from the aerial parts of Sarcomelicope megistophylla. Their structures have been elucidated on the basis of their spectral data and molecular modeling.
authors.affiliation: Laboratoire de Pharmacognosie de l'Université René Descartes, URA au CNRS No 1310, Faculté de Pharmacie, Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Fokialakis
authors.forename: S
authors.initials: S
authors.lastname: Mitaku
authors.forename: E
authors.initials: E
authors.lastname: Mikros
authors.forename: A L
authors.initials: AL
authors.lastname: Skaltsounis
authors.forename: F
authors.initials: F
authors.lastname: Tillequin
authors.forename: T
authors.initials: T
authors.lastname: Sevenet
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D002470:Cell Survival / Q000187:drug effects; D007939:Leukemia L1210; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008958:Models, Molecular; D008968:Molecular Conformation; D014197:Trees; D014407:Tumor Cells, Cultured
chemical_list: D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; C404044:megistosarcimine; C404045:megistosarconine