[Analysis of activated cells in apical granuloma].
The ratio and in situ distribution of CD3+ T-lymphocytes, CD4+ and CD8+ subsets, CD14+ macrophages, CD56+ natural killer cells and CD25+ activated T-lymphocytes and CD68+ activated macrophages were determined in 20 chronic peripical granulomas by immunohistochemical method using monoclonal antibodies. CD3+ T-lymphocytes made up about 50% of the mononuclear cells. CD14+ macrophages were distributed all over the area but their proportion was much less that that of the T-lymphocytes. CD56+ natural killer cells made up a small proportion of the cells. The major proportion of the T-lymphocytes and macrophages were in activated stage within the lesion.
Márton
I
I
Debreceni Orvostudományi Egyetem Stomatológiai Klinika.
Radics
T
T
Szakáll
S
S
Kiss
C
C
D000911:Antibodies, Monoclonal / Q000276:immunology; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D008297:Male; D010484:Periapical Granuloma / Q000276:immunology / Q000473:pathology*; D010518:Periodontitis / Q000276:immunology / Q000473:pathology*; D013601:T-Lymphocytes / Q000276:immunology
D000911:Antibodies, Monoclonal