title: ["Classic" vs autolubricant catheterization for endovesicular chemotherapy. Preliminary experience].
abstract: OBJECTIVE
  The aim of this study was to evaluate the frequency of urinary tract infections (UTI) after catheterisation for instillation comparing two systems: the "classic" method and the catheterisation using a new autolubricant device: EasiCath Coloplast.
  
  
  METHODS
  During the period of endovesical chemotherapy (between 4 and 48 weeks), 22 patients (6 females and 18 males) were studied, aged between 53 and 78 years old. We have performed 139 instillations using Nelaton Ch 14 or 12 type catheters lubricated with gel based on lidocaine, neomicyn and fluocinolone ("classic" method). Instead 135 patients have been treated with autolubricant devices according to the manufacturer's instructions. After 48 hours from instillation, a total of 274 catheterisation have been examined using urine tests and urine culture with antibiogram. We administered a 5-point visual analogic score to the patients weighing the post-instillation dysuria.
  
  
  RESULTS
  With "classic" method UTI frequency is 7.19% (10/139). The most common pathogen has been E. coli (7/10). With autolubricant catheters UTI frequency is 2.96 (4/135). Klebsiella, Enterobacter, as well as E. coli (2/4) have been identified as pathogen. All patients with infections have been treated with targeted antibiotics based on the antibiogram.
  
  
  CONCLUSIONS
  We have observed the people with autolubricant catheters left more comfort then those undergoing to the "classic" catheterisation. The frequency of post-catheterisation, dysuria was also reduced. Our data show that the new method is safer and easier to handle then the "classic" one. Moreover, common anaesthetic/antibiotic lubricant have important bacteriostatic effects that reduce the BCG viability.
authors.affiliation: Clinica Urologica, Azienda Universitaria Policlinico, Napoli.
authors.forename: L
authors.initials: L
authors.lastname: Cindolo
authors.forename: A
authors.initials: A
authors.lastname: Rega
authors.forename: M
authors.initials: M
authors.lastname: Marsicano
authors.forename: A
authors.initials: A
authors.lastname: Ginestra
authors.forename: V
authors.initials: V
authors.lastname: Guadagno
authors.forename: V
authors.initials: V
authors.lastname: Altieri
mesh_terms: D000368:Aged; D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage* / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014546:Urinary Catheterization / Q000009:adverse effects* / Q000295:instrumentation*; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D000892:Anti-Infective Agents, Urinary