title: Reversible cerebellar involvement in the idiopathic hypereosinophilic syndrome.
abstract: We report a patient with cerebellar manifestations due to the idiopathic hypereosinophilic syndrome, in whom magnetic resonance imaging (MRI) showed hyper-intense lesions in both cerebellar hemispheres. Following steroids and hydroxyurea administration, the lesions on MRI disappeared, suggesting that the pathogenetic mechanism was reversible and did not cause significant structural damage. To our knowledge, the resolution of the abnormal MRI findings have not been reported to date in the idiopathic hypereosinophilic syndrome.
authors.affiliation: Service of Internal Medicine, Hospital de Galdakao, Vizcaya, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Díaz
authors.forename: J
authors.initials: J
authors.lastname: Collazos
mesh_terms: D000368:Aged; D002526:Cerebellar Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D017681:Hypereosinophilic Syndrome / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging / Q000379:methods; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D005938:Glucocorticoids; D011241:Prednisone; D006918:Hydroxyurea