Translational repression: a duet of Nanos and Pumilio.
Recent studies have shed new light on translational repression by Nanos and Pumilio proteins. The ancestral function of this repression mechanism appears to be in early germline development; later, species-specific applications in embryonic patterning and spermatogenesis-oogenesis switching evolved.
Parisi
M
M
Department of Cell Biology, Duke University Medical Center, Box 3709, Durham, NC 27710, USA.
Lin
H
H
D000818:Animals; D019521:Body Patterning / Q000235:genetics; D029721:Drosophila Proteins; D019476:Insect Proteins / Q000235:genetics*; D008297:Male; D009866:Oogenesis / Q000235:genetics; D014176:Protein Biosynthesis; D016601:RNA-Binding Proteins; D013091:Spermatogenesis / Q000235:genetics
D029721:Drosophila Proteins; D019476:Insect Proteins; D016601:RNA-Binding Proteins; C074333:pum protein, Drosophila; C070574:nos protein, Drosophila