title: CT and MRI in severe hypophosphataemia with central nervous system involvement.
abstract: We report a 38-year-old woman with extreme hypophosphataemia in whom CT and MRI disclosed bilateral lesions within the basal ganglia, thalamus and occipital lobes. After adequate substitution of phosphate the lesions grossly resolved and the patient recovered. This case is the first to demonstrate that profound changes of serum phosphate may be associated with reversible brain lesions.
authors.affiliation: Department of Radiology, Krankenhaus Am Urban, Dieffenbachstrasse 1, 10967 Berlin, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Weber
authors.forename: T
authors.initials: T
authors.lastname: Hüppe
authors.forename: L
authors.initials: L
authors.lastname: Niehaus
mesh_terms: D000328:Adult; D001480:Basal Ganglia Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging; D001927:Brain Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D017674:Hypophosphatemia / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D009778:Occipital Lobe / Q000000981:diagnostic imaging / Q000473:pathology; D010710:Phosphates / Q000097:blood / Q000627:therapeutic use; D013786:Thalamic Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: D010710:Phosphates