title: Echocardiographic evaluation in children treated with CAPD.
abstract: The aim of this study was to evaluate systolic and diastolic cardiac functions in children treated with continuous ambulatory peritoneal dialysis (CAPD). This study included a total of 21 patients (12 boys, 9 girls), aged 23 months to 14 years (average age: 10.1 +/- 4.32 years). The mean duration on CAPD was 12.88 +/- 6.69 months (range: 2-22 months). Twenty age- and sex-matched healthy subjects served as controls. Evaluation was made at the beginning of CAPD treatment in these 21 patients. Tests were repeated in 9 of 21 patients who had completed a 1-year follow-up period. We measured systolic functions [ejection fraction (EF), and fractional shortening (FS)], and diastolic functions [early (E) and late (A) diastolic peak inflow velocities, and E/A ratio, as well as early diastolic flow deceleration velocity (EF slope) and time (dt) functions] using two-dimensional, M-mode, color Doppler echocardiography. Interventricular septum thickness was also recorded. Blood pressure (BP) levels were monitored serially in all patients. Statistical evaluation was made using Student's t-test. Compared with control subjects, systolic and diastolic parameters were significantly inversely affected in patients on CAPD (P < 0.05). The mean BP levels did not differ significantly between CAPD patients and controls. In 9 patients with a second measurement on CAPD, systolic and diastolic cardiac functions tended to have deteriorated. However, these changes were not statistically significant (P > 0.05). In conclusion, CAPD is the preferable option in children with end-stage renal disease to maintain stable cardiac functions. However, systolic and diastolic dysfunctions tend to progress in children on CAPD.
authors.affiliation: Department of Pediatric Nephrology, SSK Tepecik Teaching Hospital, Yenisehir, Izmir, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Aksu
authors.forename: O
authors.initials: O
authors.lastname: Yavascan
authors.forename: H
authors.initials: H
authors.lastname: Erdogan
authors.forename: M C
authors.initials: MC
authors.lastname: Dorak
authors.forename: S
authors.initials: S
authors.lastname: Kansoy
authors.forename: M
authors.initials: M
authors.lastname: Kozan
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D018618:Echocardiography, Doppler, Color; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D008297:Male; D010531:Peritoneal Dialysis, Continuous Ambulatory; D016277:Ventricular Function, Left