Effect of support materials on cephamycin C production by immobilized Streptomyces clavuligerus.
In order to know the effect of supports on cephamycin C production, under similar experimental conditions, S. clavuligerus cells were immobilized with--sponge, 2% agar, 2% and 4% alginate support materials. An experimental set of free cell was also maintained as control. Cephamycin C production by these immobilized and free cells was estimated at 48, 96 and 120 hr of fermentation. In all the cases cephamycin C production was found to be high at 120 hr of fermentation. Sponge was found to be a better support material than other supports used for immobilization.
Sridevi
V
V
Department of Microbiology, Osmania University, Hyderabad, India.
Sridhar
P
P
D001709:Biotechnology; D002513:Cephamycins / Q000096:biosynthesis*; D005285:Fermentation; D013302:Streptomyces / Q000378:metabolism*
D002513:Cephamycins; C024925:cephamycin C