Two novel anti-emetic principles of Alpinia katsumadai.
Two novel diarylheptanoids named katsumadain A (1) and katsumadain B (2) were isolated from the seeds of Alpinia katsumadai, and their structures were determined by spectroscopic analysis. Both katsumadains A (1) and B (2) showed anti-emetic activities on copper sulfate-induced emesis in young chicks.
Yang
Y
Y
Department of Pharmacognosy and Phytochemistry, Meiji Pharmaceutical University, Tokyo, Japan.
Kinoshita
K
K
Koyama
K
K
Takahashi
K
K
Tai
T
T
Nunoura
Y
Y
Watanabe
K
K
D000818:Animals; D000932:Antiemetics / Q000302:isolation & purification*; D002645:Chickens; D036381:Diarylheptanoids; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification*; D008956:Models, Chemical; D011753:Pyrones / Q000302:isolation & purification*; D012639:Seeds / Q000737:chemistry; D019862:Zingiberales / Q000737:chemistry*
D000932:Antiemetics; D036381:Diarylheptanoids; D004365:Drugs, Chinese Herbal; D011753:Pyrones; C404385:katsumadain A; C404386:katsumadain B