title: Do hormonal indices of maturation explain energy expenditure differences in African American and Caucasian prepubertal children?
abstract: OBJECTIVE
  To examine the relationships between hormonal indices of maturation and total, resting and physical activity-related energy expenditure (TEE, REE and AEE) in African American and Caucasian prepubertal children.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  Sixty-four African American and 48 Caucasian prepubertal children.
  
  
  METHODS
  TEE (by doubly labeled water), REE (by indirect calorimetry), fat mass and fat-free mass (by dual-energy X-ray absorptiometry), fasting serum dehydroepiandrosterone-sulfate (DHEAS), androstenedione, and estrone-sulfate (by radioimmunoassay).
  
  
  RESULTS
  Serum concentrations of hormones correlated significantly with REE and TEE (r values range from 0.33 to 0.76, P<0.001). Only androstenedione correlated significantly with AEE (r = 0.23, P<0.05). However, these correlations were no longer significant after adjusting energy expenditure components for fat-free mass. In multiple regression models, ethnicity was not a significant determinant of any energy expenditure component after adjusting for body composition and hormone concentrations.
  
  
  CONCLUSIONS
  Hormonal indices of maturation do not influence energy expenditure in this group of African American and Caucasian prepubertal children.
authors.affiliation: Department of Nutrition Sciences, University of Alabama at Birmingham, 35294, USA.
authors.forename: M
authors.initials: M
authors.lastname: Sun
authors.forename: B A
authors.initials: BA
authors.lastname: Gower
authors.forename: T R
authors.initials: TR
authors.lastname: Nagy
authors.forename: A A
authors.initials: AA
authors.lastname: Bartolucci
authors.forename: M I
authors.initials: MI
authors.lastname: Goran
mesh_terms: D000704:Analysis of Variance; D000728:Androgens / Q000097:blood*; D044383:Black People / Q000235:genetics*; D001823:Body Composition / Q000235:genetics; D002648:Child; D002657:Child Development; D003430:Cross-Sectional Studies; D004734:Energy Metabolism / Q000235:genetics*; D004967:Estrogens / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D014481:United States; D044465:White People / Q000235:genetics*; D001741:Black or African American
chemical_list: D000728:Androgens; D004967:Estrogens