Steroid sensitivity and postoperative course of seven patients with Behçet's disease.
Systemic administration of steroids to patients with Behçet's disease in Japan is often followed by a worsening in ocular symptoms. The sensitivity of 7 patients with Behçet's disease to steroids which were administered during and after intraocular surgery was therefore measured, and their postoperative course was reviewed. Three of the 7 showed a low steroid sensitivity, and the frequency of postoperative inflammatory episodes and the intraocular pressure were both higher for this group than for the 4 who showed high steroid sensitivity.
Tanaka
T
T
Department of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan. takaoeye@msh.biglobe.ne.jp
Suzuki
J
J
Yamakawa
N
N
Usui
M
M
D000328:Adult; D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis; D001528:Behcet Syndrome / Q000139:chemically induced* / Q000276:immunology / Q000503:physiopathology; D001623:Betamethasone / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology* / Q000276:immunology / Q000503:physiopathology; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D007429:Intraocular Pressure; D037181:Lectins, C-Type; D019654:Lens Implantation, Intraocular; D008213:Lymphocyte Activation / Q000276:immunology; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D000099192:CD69 Antigens
D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D001623:Betamethasone; D005938:Glucocorticoids; D037181:Lectins, C-Type; D000099192:CD69 Antigens