[Novel lipoprotein-binding proteins p105 and p130 in smooth muscles of human vessels: structure, expression, and possible physiological role].
The expression level of two new lipoprotein-binding proteins p105 and p130 was maximal in inactive VSMC and could be suppressed by activators of proliferation. Both proteins were detected by antisera against three synthetic fragments of T-cadherin and were rendered soluble by GPI-specific phospholipase C. The findings suggest that the 105 kDa lipoprotein-binding protein is T-cadherin whereas p130 is a partially processed GPI-anchored precursor of T-cadherin.
Bochkov
V N
VN
Cardiological Research-Industrial Complex, Moscow, Russia.
Filippova
M P
MP
Stambol'skiĭ
D V
DV
Tkachuk
V A
VA
D000293:Adolescent; D000328:Adult; D000595:Amino Acid Sequence; D001011:Aorta / Q000378:metabolism; D015820:Cadherins / Q000235:genetics / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D006801:Humans; D015151:Immunoblotting; D008875:Middle Aged; D008969:Molecular Sequence Data; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D011498:Protein Precursors / Q000235:genetics / Q000378:metabolism; D018110:Receptors, Lipoprotein / Q000235:genetics* / Q000378:metabolism; D017386:Sequence Homology, Amino Acid
D015820:Cadherins; C099972:H-cadherin; D011498:Protein Precursors; D018110:Receptors, Lipoprotein