Enzymatic Synthesis of Neoglycopeptide Building Blocks.
A transglutaminase-catalyzed transacylation is the major step in a practical, regioselective synthesis of N-linked spacer-modified glycopeptide analogues. The process requires minimal modification of the saccharide during the N-glycosylation, photoinduced coupling of cysteamine, and final enzymatic reaction (see scheme).
Ramos
D
Unilever Research Vlaardingen 3133 AT Vlaardingen (The Netherlands).
Rollin
P
Klaffke
W