title: [Cancer chemotherapy based on evidence--metastatic breast cancer].
abstract: Breast cancer is relatively sensitive to chemotherapy. However, although response rate to chemotherapy is reported to be from 50 to 70% in metastatic breast cancer, it is incurable. Current standard chemotherapeutic regimens do not provide a large survival benefit according to the evidence obtained from clinical studies. Before developing a treatment program, we should therefore realize that the aims of chemotherapy for metastatic breast cancer are improvement of quality of life through relief of symptoms, and prolonging survival.
authors.affiliation: Dept. of Surgery, National Shikoku Cancer Center Hospital, Matsuyama, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Takashima
authors.forename: T
authors.initials: T
authors.lastname: Saeki
authors.forename: S
authors.initials: S
authors.lastname: Ohsumi
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D001952:Bridged-Ring Compounds / Q000008:administration & dosage; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D015201:Meta-Analysis as Topic; D009362:Neoplasm Metastasis; D011788:Quality of Life; D043823:Taxoids
chemical_list: D001952:Bridged-Ring Compounds; D043823:Taxoids; C080625:taxane