Linkage disequilibrium, gene trees and selfing: an ancestral recombination graph with partial self-fertilization.
It is shown that partial self-fertilization can be introduced into neutral population genetic models with recombination as a simple change in the scaling of the parameters. This means that statistical and computational methods that have been developed under the assumption of random mating can be used without modification, provided the appropriate parameter changes are made. An important prediction is that all forms of linkage disequilibrium will be more extensive in selfing species. The implications of this are discussed.
Nordborg
M
M
Department of Genetics, Lund University, S-223 62 Lund, Sweden. magnus.nordborg@gen.lu.se
D015810:Linkage Disequilibrium; D009010:Monte Carlo Method; D011110:Polymorphism, Genetic; D011995:Recombination, Genetic