The metabolic response to acute traumatic brain injury and implications for nutritional support.
An overview of the metabolic response to acute traumatic brain injury is presented. The consequences of hypermetabolism, hypercatabolism, and an altered immune function are discussed. Once a person with acute traumatic brain injury develops this hyperdynamic state, the resultant excessive protein breakdown ensues. This can lead to malnutrition. The feeding methods used to prevent malnutrition are discussed, along with the proper alimentation to provide to diminish the hyperdynamic state and improve immune function.
Pepe
J L
JL
Surgical Critical Care, Saint Francis Hospital and Medical Center, Hartford, Connecticut 06105, USA.
Barba
C A
CA
D000208:Acute Disease; D000367:Age Factors; D000465:Algorithms; D001827:Body Height; D001835:Body Weight; D001930:Brain Injuries / Q000150:complications / Q000276:immunology / Q000378:metabolism* / Q000628:therapy*; D003663:Decision Trees; D004734:Energy Metabolism; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D008297:Male; D015596:Nutrition Assessment; D009748:Nutrition Disorders / Q000209:etiology / Q000517:prevention & control; D009751:Nutritional Requirements; D018529:Nutritional Support / Q000379:methods*; D018579:Patient Selection; D012737:Sex Factors