Studies on quinoxaline derivatives. Synthesis of quinoxalylamino-1,3-diazacycloalkanes with potential hypotensive activity.
A series of quinoxalylamino-1,3-diazacycloalkanes was obtained by the reaction of the corresponding substituted aminoquinoxalines with alcohols and amines. The effect of selected compounds on the blood pressure of anaesthesized normotensive rats was studied.
Foks
H
H
Department of Organic Chemistry, Medical University of Gdańsk.
Wisterowicz
K
K
Nasal
A
A
Damasiewicz
B
B
Radwańska
A
A
D000818:Animals; D000959:Antihypertensive Agents / Q000138:chemical synthesis / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D002317:Cardiovascular Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D008297:Male; D011810:Quinoxalines / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar
D000959:Antihypertensive Agents; D002317:Cardiovascular Agents; D011810:Quinoxalines