title: [Mechanism of leukemogenesis induced by AML 1-MTG 8].
authors.affiliation: Radiobiology Division, National Cancer Center Research Institute, Tokyo, Japan. ikitabay@gan2.ncc.go.jp
authors.forename: I
authors.initials: I
authors.lastname: Kitabayashi
authors.forename: M
authors.initials: M
authors.lastname: Ohki
mesh_terms: D000123:Acetyltransferases / Q000502:physiology; D000818:Animals; D019677:Artificial Gene Fusion; D002454:Cell Differentiation / Q000235:genetics; D002891:Chromosomes, Human, Pair 21; D002898:Chromosomes, Human, Pair 8; D050676:Core Binding Factor Alpha 2 Subunit; D004268:DNA-Binding Proteins / Q000235:genetics / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental; D015972:Gene Expression Regulation, Neoplastic; D006655:Histone Deacetylases / Q000502:physiology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000473:pathology; D009504:Neutrophils / Q000166:cytology; D010750:Phosphoproteins / Q000502:physiology; D011485:Protein Binding; D011518:Proto-Oncogene Proteins; D000075142:RUNX1 Translocation Partner 1 Protein; D012097:Repressor Proteins / Q000502:physiology; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology*; D014178:Translocation, Genetic
chemical_list: C110408:CBFA2T2 myeloid-transforming gene-related protein; D050676:Core Binding Factor Alpha 2 Subunit; D004268:DNA-Binding Proteins; D010750:Phosphoproteins; D011518:Proto-Oncogene Proteins; D000075142:RUNX1 Translocation Partner 1 Protein; C493728:RUNX1 protein, human; C082222:RUNX1T1 protein, human; D012097:Repressor Proteins; D014157:Transcription Factors; D000123:Acetyltransferases; D006655:Histone Deacetylases