title: Common DPYD mutation associated with 5-fluorouracil toxicity detected by PCR-mediated site-directed mutagenesis.
authors.forename: P
authors.initials: P
authors.lastname: Jézéquel
authors.forename: M P
authors.initials: MP
authors.lastname: Joalland
authors.forename: G
authors.initials: G
authors.lastname: Milano
authors.forename: D
authors.initials: D
authors.lastname: Lanoë
authors.forename: G
authors.initials: G
authors.lastname: Ricolleau
authors.forename: E
authors.initials: E
authors.lastname: Marie-Christine
authors.forename: R
authors.initials: R
authors.lastname: Deporte-Fety
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans; D016297:Mutagenesis, Site-Directed; D009154:Mutation; D010088:Oxidoreductases / Q000235:genetics*; D016133:Polymerase Chain Reaction
chemical_list: D000964:Antimetabolites, Antineoplastic; D010088:Oxidoreductases; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil