Anorectic activity of 2H-4,6-dimethyl-2-[(4-phenylpiperazin-1- yl)methyl]-3-oxo-2,3-dihydroisothiazolo[5,4-b]pyridine.
The effect of 2H-4,5-dimethyl-2-[(4-phenylpiperazin-1-yl)methyl]-3- oxo-2,3-dihydroisothiazolo[5,4-b]pyridine on feeding in rats was investigated. The tested compound decreased food intake in food-deprived rats and in rats receiving palatable-diet.
Rutkowska
M
M
Department of Pharmacology, Wrocław University of Medicine, Poland.
D000818:Animals; D001067:Appetite Depressants / Q000494:pharmacology*; D004435:Eating / Q000187:drug effects*; D008297:Male; D011725:Pyridines / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
D001067:Appetite Depressants; D011725:Pyridines