Pyoderma gangrenosum and Chlamydia pneumoniae infection in a diabetic man: pathogenic role or coincidence?
Chlamydia Pneumoniae is not a known cause of skin infections, but unusual pathogens cause chronic infections in diabetic patients. Multiple idiopathic pyoderma gangrenosum-like (PG-like) lesions were refractory to multiple therapeutic agents in a diabetic patient who had C pneumoniae identified by serologic tests and polymerase chain reaction. Based on complete resolution by prolonged anti-chlamydial antibiotic therapy and concomitant decrease in serologic and titers determined by polymerase chain reactions, the PG-like lesions were presumed to be due to C pneumoniae.
Vannucci
S A
SA
Department of Medicine, Division of Dermatology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-5227, USA.
Mitchell
W M
WM
Stratton
C W
CW
King
L E
LE
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002690:Chlamydia Infections / Q000150:complications*; D016993:Chlamydophila pneumoniae / Q000472:pathogenicity*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000382:microbiology; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D017511:Pyoderma Gangrenosum / Q000209:etiology* / Q000382:microbiology
D000900:Anti-Bacterial Agents