title: Effect of mechanical surface pretreatment on metal ion release.
abstract: The degree of metal ion dissolution from Ti-6Al-4V alloy hip replacement stems subjected to various mechanical and chemical surface pretreatments was analysed in vitro. High-dissolution rates were observed for nitric acid passivated samples that had been mechanically surface treated to increase the implant surface area. Significantly lower ion release levels were observed for mechanically treated samples which had been aged in de-ionised water. The application of an hydroxyapatite coating decreased the metal ion release from the nitric acid passivated samples (compared to the uncoated sample) and increased the metal ion dissolution from the aged samples. The dissolution behaviour of the samples is explained in terms of the diffusion processes occurring at the stem/solution interface and the morphological and chemical characteristics of the surface treated stems.
authors.affiliation: School of Engineering Sciences, Materials Group, University of Southampton, UK.
authors.forename: M
authors.initials: M
authors.lastname: Browne
authors.forename: P J
authors.initials: PJ
authors.lastname: Gregson
mesh_terms: D000497:Alloys / Q000737:chemistry*; D000818:Animals; D002412:Cations; D002417:Cattle; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D017886:Durapatite; D006622:Hip Prosthesis; D007700:Kinetics; D008670:Metals / Q000737:chemistry*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
chemical_list: D000497:Alloys; D002412:Cations; D020099:Coated Materials, Biocompatible; D008670:Metals; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium