title: An iterative approach to the beam hardening correction in cone beam CT.
abstract: In computed tomography (CT), the beam hardening effect has been known to be one of the major sources of deterministic error that leads to inaccuracy and artifact in the reconstructed images. Because of the polychromatic nature of the x-ray source used in CT and the energy-dependent attenuation of most materials, Beer's law no longer holds. As a result, errors are present in the acquired line integrals or measurements of the attenuation coefficients of the scanned object. In the past, many studies have been conducted to combat image artifacts induced by beam hardening. In this paper, we present an iterative beam hardening correction approach for cone beam CT. An algorithm that utilizes a tilted parallel beam geometry is developed and subsequently employed to estimate the projection error and obtain an error estimation image, which is then subtracted from the initial reconstruction. A theoretical analysis is performed to investigate the accuracy of our methods. Phantom and animal experiments are conducted to demonstrate the effectiveness of our approach.
authors.affiliation: Applied Science Laboratory, GE Medical Systems, Milwaukee, Wisconsin 53201, USA. jiang.hsieh@med.ge.com
authors.forename: J
authors.initials: J
authors.lastname: Hsieh
authors.forename: R C
authors.initials: RC
authors.lastname: Molthen
authors.forename: C A
authors.initials: CA
authors.lastname: Dawson
authors.forename: R H
authors.initials: RH
authors.lastname: Johnson
mesh_terms: D000465:Algorithms; D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000706:statistics & numerical data; D008168:Lung / Q000000981:diagnostic imaging; D019047:Phantoms, Imaging; D051381:Rats; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data*