Sigma binding sites identified by [(3)H] DTG are elevated in aged Fischer-344 x Brown Norway (F1) rats.
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Department of Pharmacology and Physiology, Oklahoma State University College of Osteopathic Medicine, Tulsa, Oklahoma 74107-1898, USA.
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D000375:Aging / Q000378:metabolism*; D000818:Animals; D000927:Anticonvulsants / Q000493:pharmacokinetics*; D001665:Binding Sites; D003342:Corpus Striatum / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D006146:Guanidines / Q000493:pharmacokinetics*; D006220:Haloperidol / Q000494:pharmacology; D008297:Male; D020891:Raclopride / Q000493:pharmacokinetics; D051381:Rats; D011914:Rats, Inbred BN; D011916:Rats, Inbred F344; D017448:Receptors, Dopamine D2 / Q000032:analysis / Q000378:metabolism*; D017480:Receptors, sigma / Q000032:analysis / Q000378:metabolism*; D014316:Tritium
D000927:Anticonvulsants; D006146:Guanidines; D017448:Receptors, Dopamine D2; D017480:Receptors, sigma; D014316:Tritium; D020891:Raclopride; D006220:Haloperidol; C050232:1,3-ditolylguanidine