title: A new biflavonoid from Calophyllum panciflorum with antitumor-promoting activity.
abstract: A new biflavonoid named pancibiflavonol (1) was isolated from an EtOH extract of the stem bark of Calophyllum panciflorum, along with six known biflavonoids, and its structure was elucidated by spectroscopic methods. These biflavonoids all exhibited significant inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus early antigen activation in Raji cells.
authors.affiliation: Faculty of Pharmacy, Meijo University, Nagoya, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Ito
authors.forename: M
authors.initials: M
authors.lastname: Itoigawa
authors.forename: Y
authors.initials: Y
authors.lastname: Miyamoto
authors.forename: K S
authors.initials: KS
authors.lastname: Rao
authors.forename: J
authors.initials: J
authors.lastname: Takayasu
authors.forename: Y
authors.initials: Y
authors.lastname: Okuda
authors.forename: T
authors.initials: T
authors.lastname: Mukainaka
authors.forename: H
authors.initials: H
authors.lastname: Tokuda
authors.forename: H
authors.initials: H
authors.lastname: Nishino
authors.forename: H
authors.initials: H
authors.lastname: Furukawa
mesh_terms: D000970:Antineoplastic Agents / Q000302:isolation & purification*; D002460:Cell Line; D002472:Cell Transformation, Viral / Q000187:drug effects; D005419:Flavonoids / Q000302:isolation & purification*; D044948:Flavonols; D004854:Herpesvirus 4, Human; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D014197:Trees / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D005419:Flavonoids; D044948:Flavonols; C404384:pancibiflavonol