MR spectroscopy and imaging in metabolic myopathies.
Magnetic resonance spectroscopy and imaging of muscle and brain offers new possibilities for noninvasive diagnosis of metabolic myopathies. These functional techniques allow assessment of the pathophysiology of these disorders and also can be used for monitoring disease evolution and response to therapy. In this article, the authors review the magnetic resonance spectroscopy and imaging features of mitochondrial encephalomyopathies, glycolytic disorders, and hypothyroidism.
Argov
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Associate Professor, Department of Neurology, Hadassah University Hospital, Jerusalem.
Arnold
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D000255:Adenosine Triphosphate / Q000378:metabolism; D001921:Brain / Q000503:physiopathology; D004734:Energy Metabolism / Q000502:physiology; D005080:Exercise Test; D006019:Glycolysis / Q000502:physiology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008659:Metabolic Diseases / Q000175:diagnosis* / Q000503:physiopathology; D017237:Mitochondrial Encephalomyopathies / Q000175:diagnosis / Q000503:physiopathology; D018482:Muscle, Skeletal / Q000503:physiopathology; D009135:Muscular Diseases / Q000175:diagnosis* / Q000503:physiopathology; D009468:Neuromuscular Diseases / Q000175:diagnosis / Q000503:physiopathology
D000255:Adenosine Triphosphate