title: Scintigraphic evaluation of colonic transit in two patients with idiopathic chronic constipation.
abstract: Bowel transit in two women with protracted constipation was evaluated after oral administration of In-111 DTPA in water. Serial abdominal images were obtained for as long as 96 hours to assess transit through the stomach, small bowel, and colon. In both patients, large bowel transit was delayed. A pattern of colonic inertia was observed in one patient, whereas retention in the distal colon was seen in the other patient. Both patients underwent total colectomy with marked symptomatic relief. Colonic transit studies of these patients are presented, and the literature is reviewed.
authors.affiliation: Division of Nuclear Medicine and Gastroenterology, Danbury Hospital, Connecticut 06810, USA.
authors.forename: A
authors.initials: A
authors.lastname: Ramachandran
authors.forename: S M
authors.initials: SM
authors.lastname: Gupta
authors.forename: T
authors.initials: T
authors.lastname: Whelan
authors.forename: W
authors.initials: W
authors.lastname: Johns
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003106:Colon / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003248:Constipation / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D005772:Gastrointestinal Transit / Q000502:physiology*; D006801:Humans; D007205:Indium Radioisotopes; D008875:Middle Aged; D004369:Pentetic Acid; D011877:Radionuclide Imaging
chemical_list: D007205:Indium Radioisotopes; D004369:Pentetic Acid