[Chronic congenital Coxsackie virus infection in the etiology of allergic disease in children].
The authors prove the involvement of congenital Coxsackie virus infection in the etiology of allergic diseases in children: 1) indications of high risk of vertical transmission of viruses of this group from mothers with persistent infection to children are more incident in the history of mothers whose children develop allergies in comparison with healthy age-matched children (83 vs. 38.8%); 2) Coxsackie viruses are detected in sick children more often than in healthy ones (58.1-81.1 vs. 7.4%); 3) the persistence of Coxsackie A and B viruses is confirmed in the majority of patients examined over time; 4) in the mothers examined in parallel with their sick children Coxsackie viruses were detected virtually as often as in their children; and 5) reduction of endogenous chronic Coxsackie infection by energy metabolism correction in the risk group women during pregnancy prevents the development of allergic diseases in their children.
Lozovskaia
L S
LS
Ermakova
M K
MK
Menemchiadis
G I
GI
Konopleva
T N
TN
Khellenova
E A
EA
D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003384:Coxsackievirus Infections / Q000150:complications* / Q000151:congenital; D004770:Enterovirus / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology*; D007223:Infant; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects