title: Rare polymorphisms in the promoter regions of the human interleukin-12 p35 and interleukin-12 p40 subunit genes.
abstract: We have described two rare, single-nucleotide polymorphisms within the promoter regions of the IL-12 p35 and p40 subunit genes. Transitions C to T at position -916 from the transcription start of the IL-12 p35 gene and G to T at position -1287 in the IL-12 p40 gene were observed.
authors.affiliation: Immunology Research Group, School of Biological Sciences, University of Manchester, UK.
authors.forename: V
authors.initials: V
authors.lastname: Pravica
authors.forename: I J
authors.initials: IJ
authors.lastname: Brogan
authors.forename: I V
authors.initials: IV
authors.lastname: Hutchinson
mesh_terms: D001483:Base Sequence; D017124:Conserved Sequence; D014644:Genetic Variation; D006801:Humans; D018664:Interleukin-12 / Q000235:genetics*; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D018807:Polymorphism, Single-Stranded Conformational; D011401:Promoter Regions, Genetic
chemical_list: D018664:Interleukin-12