[Mechanogenic regulation of the tonus and reactivity of blood vessels].
In acute experiments on cats and rats, as well as on isolated segments of the rat mesenteric and tail arteries, the parameters of myogenic and endothelium-dependent regulation of the blood vessels were studied. An important role of mechanical stimulation of the endothelium in development of vasodilatation in the skeletal muscles along with the increase of the pressure pulse amplitude, was revealed. A diminution of endothelium-dependent vasodilatation was shown in spontaneously hypertensive rats in an increase of the pulse pressure.
Dvoretskiĭ
D P
DP
I. P. Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg, Russia.
D000818:Animals; D001158:Arteries / Q000502:physiology; D001808:Blood Vessels / Q000502:physiology*; D004730:Endothelium, Vascular / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology; D008833:Microcirculation; D009129:Muscle Tonus / Q000502:physiology*; D018482:Muscle, Skeletal / Q000098:blood supply; D014664:Vasodilation / Q000502:physiology