Cardiotoxic potential and CNS effects of first-generation antihistamines.
Taglialatela
M
M
Section of Pharmacology, Department of Neuroscience, School of Medicine, University of Naples Federico II, Naples, Italy. mtaglial@unina.it
Timmerman
H
H
Annunziato
L
L
D000818:Animals; D002490:Central Nervous System / Q000187:drug effects* / Q000502:physiology; D004155:Diphenhydramine / Q000009:adverse effects / Q000494:pharmacology; D004594:Electrophysiology; D006321:Heart / Q000187:drug effects* / Q000502:physiology; D006634:Histamine H1 Antagonists / Q000009:adverse effects* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D006919:Hydroxyzine / Q000009:adverse effects / Q000494:pharmacology; D026902:Potassium Channel Blockers; D015221:Potassium Channels / Q000378:metabolism; D011969:Receptors, Histamine H1 / Q000378:metabolism; D013329:Structure-Activity Relationship
D006634:Histamine H1 Antagonists; D026902:Potassium Channel Blockers; D015221:Potassium Channels; D011969:Receptors, Histamine H1; D006919:Hydroxyzine; D004155:Diphenhydramine