title: The antimicrobial activity of roots of Jatropha podagrica (Hook).
abstract: Hexane, chloroform and methanol extracts of the rootwood and rootbarks of Jatropha podagrica were studied for their antimicrobial activity against 18 organisms. All the extracts exhibited some broad spectrum antibacterial activity, at a concentration of 20 mg/mL. The hexane extracts were generally more active than the chloroform and methanol extracts. The hexane extract of the yellow rootbark was the most active of all the extracts and its activity was comparable to that of gentamycin but better with regard to the control of S. aureus and B. cereus. Three of the extracts, hexane extract of the yellow rootbark and hexane and methanol extracts of the rootwood showed moderate antifungal activity against the yeast fungus, Candida albicans.
authors.affiliation: Department of Chemistry, University of Ibadan, Ibadan, Nigeria.
authors.forename: O O
authors.initials: OO
authors.lastname: Aiyelaagbe
authors.forename: E K
authors.initials: EK
authors.lastname: Adesogan
authors.forename: O
authors.initials: O
authors.lastname: Ekundayo
authors.forename: B A
authors.initials: BA
authors.lastname: Adeniyi
mesh_terms: D000890:Anti-Infective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D019665:Euphorbiaceae / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D018517:Plant Roots / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents