[Inward rectifier potassium current in the frog embryonic skeletal myocytes].
Pharmacological and kinetic properties of the inward rectifier potassium current Iir the frog embryonic skeletal myocytes were found to be identical to those of adult frog skeletal muscle fibres. The data obtained suggest that the Iir plays the main role in maintaining the myocytes resting membrane potential (RMP) when chloride conductance is insignificant. Changes of the integral conductance Gir and the RMP values correlated with the T-system development. The inward rectifier K+ channels, from the early stages of the muscle seem to be located in the T-tubule membranes.
Katina
I E
IE
Ukhtomsky Institute of Physiology, St. Petersburg State University, Russia.
Terent'ev
D A
DA
Nasledov
G A
GA
D000818:Animals; D002478:Cells, Cultured; D008564:Membrane Potentials; D018482:Muscle, Skeletal / Q000166:cytology / Q000502:physiology*; D018408:Patch-Clamp Techniques; D015221:Potassium Channels / Q000502:physiology*; D024661:Potassium Channels, Inwardly Rectifying; D011896:Rana temporaria
D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying