title: [Primary solitary malignant schwannoma of the trigeminal nerve, Report of a case and review of the literature].
abstract: We present the case of a primary solitary malignant schwannoma of the trigeminal nerve. A total of 55 cases have been described in the literature; however, in these cases two tumors were affecting the supraorbital branch. This nerve-sheath tumor usually affects men in the fifth decade of life. The main clinical sign of malignant schwannomas of the head and neck is an indolent swelling. Hematogenic or lymphogenic metastasis has not been described. Because of the pleomorphism of the tumor cells immunohistochemical study is important. The treatment of choice is radical resection, possibly with adjuvant radio- or chemotherapy. The 5-year survival rate of malignant schwannoma of the trigeminal nerve is 41.7%.
authors.affiliation: Abteilung für Mund-, Kiefer- und Gesichtschirurgie, Universität Hamburg-Eppendorf.
authors.forename: H C
authors.initials: HC
authors.lastname: Moeller
authors.forename: M
authors.initials: M
authors.lastname: Heiland
authors.forename: M
authors.initials: M
authors.lastname: Vesper
authors.forename: D
authors.initials: D
authors.lastname: Hellner
authors.forename: R
authors.initials: R
authors.lastname: Schmelzle
mesh_terms: D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D009380:Neoplasms, Nerve Tissue / Q000473:pathology / Q000601:surgery*; D009442:Neurilemmoma / Q000473:pathology / Q000601:surgery*; D011182:Postoperative Care; D015996:Survival Rate; D016896:Treatment Outcome; D014276:Trigeminal Nerve / Q000473:pathology / Q000601:surgery*