title: Allergic management of Meniere's disease: an outcome study.
abstract: The effect of allergy immunotherapy and elimination of suspected food allergens was evaluated in patients with Meniere's disease. A total of 137 patients with Meniere's disease for whom allergy treatment had been recommended were identified and were mailed and returned a symptoms questionnaire. One hundred thirteen had received allergy treatment; 24 did not have treatment and served as a control group. Information regarding history, signs and symptoms, allergy test results, and audiologic data were obtained by chart review. The 113 patients treated with desensitization and diet showed a significant improvement from pretreatment to posttreatment in both allergy and Meniere's symptoms. Ratings of frequency, severity, and interference with everyday activities of their Meniere's symptoms also appeared better after allergy treatment than ratings from the control group of untreated patients. Vertigo control results, by use of the American Academy of Otolaryngology-Head and Neck Surgery classification, categorized 47.9% as class A or B. Hearing was stable or improved in 61.4%. Patients with Meniere's disease can show improvement in their symptoms of tinnitus and vertigo when receiving specific allergy therapy. The inner ear may be the target, directly or indirectly, of an allergic reaction.
authors.affiliation: House Ear Clinic and House Ear Institute, Los Angeles, CA 90057, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Derebery
mesh_terms: D003888:Desensitization, Immunologic; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications / Q000178:diet therapy; D006801:Humans; D006967:Hypersensitivity / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D008575:Meniere Disease / Q000209:etiology* / Q000503:physiopathology; D008875:Middle Aged; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D014717:Vertigo / Q000209:etiology