Erdheim Chester disease: a rare cause of knee and leg pain.
A case of Erdheim Chester disease in a 51-year-old Turkish patient is described. Erdheim Chester disease is a rare form of lipoid granulomatosis. Knee and leg pain are the most common symptoms, and physicians working in orthopaedics and traumatology are the first to be consulted. Our patient demonstrated a typical bilateral, symmetric sclerosis of the metaphyseal region of long bones of the lower extremity, histologic examination revealed foamy, lipid-loaded histiocytes. The patient also suffered from arterial hypertension, diabetes insipidus and exophthalmos of the left eye. The diagnosis was confirmed by a bone biopsy, and the patient was treated with non-steroidal anti-inflammatory drugs, corticosteroids and vincristine.
Sistermann
R
R
Orthopädische Klinik, Städtische Kliniken Dortmund, Klinikzentrum Mitte, Germany. dr.si@t-online.de
Katthagen
B D
BD
D006099:Granuloma / Q000150:complications*; D006801:Humans; D007717:Knee; D007866:Leg; D008297:Male; D008875:Middle Aged; D010026:Osteosclerosis / Q000150:complications* / Q000000981:diagnostic imaging; D010146:Pain / Q000209:etiology*; D011859:Radiography; D013577:Syndrome