Role of alcoholic extract of shoot of Hypericum perforatum Linn on lipid peroxidation and various species of free radicals in rats.
The alcoholic extract of the shoot of H. perforatum shows strong antioxidant property. It possesses the iron chelation property with more affinity to the ferrous form. It has scavenging property for both superoxide and for hydroxyl radicals but the response is more towards the superoxide radicals. Thus in addition to the anti-depressant property it has strong antioxidant property also.
Tripathi
Y B
YB
Department of Medicinal Chemistry, Banaras Hindu University, Varanasi, India.
Pandey
E
E
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000494:pharmacology; D005609:Free Radicals / Q000378:metabolism; D020902:Hypericum / Q000737:chemistry*; D007502:Iron Chelating Agents / Q000494:pharmacology; D015227:Lipid Peroxidation / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats
D000975:Antioxidants; D016166:Free Radical Scavengers; D005609:Free Radicals; D007502:Iron Chelating Agents; D010936:Plant Extracts