Serotype-converting bacteriophages and O-antigen modification in Shigella flexneri.
O-antigen modification (serotype conversion) in Shigella flexneri, which is an important virulence determinant, is conferred by temperate bacteriophages. Several serotype-converting phages have been isolated and preliminary characterization has identified the genes involved in O-antigen modification, and has also provided insight into the molecular biology of these phages.
Allison
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GE
Divn of Biochemistry and Molecular Biology, Faculty of Science, Australian National University, Canberra, ACT, 0200, Australia.
Verma
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D000107:Acetylation; D001435:Bacteriophages / Q000235:genetics / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism; D005964:Glucosyltransferases / Q000378:metabolism; D019081:O Antigens / Q000096:biosynthesis* / Q000145:classification / Q000235:genetics; D012703:Serotyping; D012763:Shigella flexneri / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D014774:Virulence
D019081:O Antigens; D005964:Glucosyltransferases; D005947:Glucose