title: Postoperative necrotizing soft-tissue infections of the abdominal wall.
abstract: OBJECTIVE
  The aim of the underlying study was the evaluation of an aggressive surgical regimen for treatment of postoperative necrotizing soft-tissue infection (NSTI).
  
  
  METHODS
  Eight patients with postoperative NSTI of the abdominal wall after emergency (n=6) and elective (n=2) surgery were reviewed over a 9-year period.
  
  
  RESULTS
  Initially, three patients presented with general peritonitis. Cultured swabs from the necrotic tissue revealed three to four different types of bacteria in each patient. The mean interval between the primary operation and clinical symptoms of NSTI was 63.0 h. Control of NSTI and intra-abdominal infection was attained by scheduled re-operations on a daily basis accounting for three to six re-interventions in each patient. Temporary closure of the abdominal wall by absorbable polyglactid-acid mesh was used in six cases. Mean hospital stay was 65.3 days (18-110 days). Two of the eight patients died from cardiac arrest and multiple organ failure, respectively.
  
  
  CONCLUSIONS
  Rapid diagnosis and onset of treatment is accomplished by the surgeons' knowledge of this disease and a close follow-up of the patients in an intensive care unit.
authors.affiliation: Department of Surgery, Medical Faculty, Rhenish-Westphalian Technical University, Universitätsklinikum der RWTH, Pauwelsstrasse 30, D-52057 Aachen, Germany. Peter.Bertram@post.rwth-aachen.de
authors.forename: P
authors.initials: P
authors.lastname: Bertram
authors.forename: K H
authors.initials: KH
authors.lastname: Treutner
authors.forename: M
authors.initials: M
authors.lastname: Stumpf
authors.forename: V
authors.initials: V
authors.lastname: Schumpelick
mesh_terms: D000009:Abdominal Muscles / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002423:Cause of Death; D003646:Debridement / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D012086:Reoperation; D012189:Retrospective Studies; D018461:Soft Tissue Infections / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery*; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery*; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents