title: Adult nutrient intake as a risk factor for Parkinson's disease.
abstract: BACKGROUND
  This population-based case-control study evaluated nutrient intake as a risk factor for Parkinson's disease (PD) among people aged > or =50 years in metropolitan Detroit.
  
  
  METHODS
  Cases (n = 126) were diagnosed between 1991 and 1995 and neurologist-confirmed. Controls (n = 432) were frequency-matched for sex, age (+/-5 years) and race. Using a standardized food frequency questionnaire, subjects reported the foods they ate within the past year.
  
  
  RESULTS
  Estimating the association between PD and risk of being in the highest versus the lowest intake quartile, there were elevated odds ratios for total fat (OR 1.94, 95% confidence interval [CI] : 1.05-3.58), cholesterol (OR 2.11, 95% CI: 1.14-3.90), lutein (OR 2.52, 95% CI: 1.32-4.84) and iron (OR 1.88, 95% CI: 1.05-3.38).
  
  
  CONCLUSIONS
  These results suggest an association of PD with high intake of total fat, saturated fats, cholesterol, lutein and iron.
authors.affiliation: Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, Michigan, USA.
authors.forename: C C
authors.initials: CC
authors.lastname: Johnson
authors.forename: J M
authors.initials: JM
authors.lastname: Gorell
authors.forename: B A
authors.initials: BA
authors.lastname: Rybicki
authors.forename: K
authors.initials: K
authors.lastname: Sanders
authors.forename: E L
authors.initials: EL
authors.lastname: Peterson
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D016022:Case-Control Studies; D004041:Dietary Fats / Q000008:administration & dosage; D004435:Eating; D002149:Energy Intake; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D014975:Lutein / Q000008:administration & dosage; D008297:Male; D008824:Michigan / Q000453:epidemiology; D008875:Middle Aged; D009749:Nutrition Surveys; D010300:Parkinson Disease / Q000453:epidemiology*; D012307:Risk Factors
chemical_list: D004041:Dietary Fats; D014975:Lutein