title: 5-(beta-Cyclodextrinylamino)-5-Deoxy-alpha-D-Riboses as Models for Nuclease, Ligase, Phosphatase, and Phosphorylase.
abstract: beta-Cyclodextrin derivatives crowned with ribose rings (such as 1) catalyzed the hydrolysis, esterification, and phosphorylation of catechol-derived phosphate esters. The vicinal cis-diols on the ribose groups appear to play a major role in the catalytic activity of these enzyme models by the formation of hydrogen bonds which activate the phosphorus atom to nucleophilic attack.
authors.affiliation: Department of Molecular Science and Technology Ajou University, Suwon 442-749 (Korea).
authors.initials: MJ
authors.lastname: Han
authors.initials: KS
authors.lastname: Yoo
authors.initials: JY
authors.lastname: Chang
authors.initials: TK
authors.lastname: Ha