Cytokeratin fragment 19 (CYFRA 21-1) in healthy smokers.
Two hundred and ninety-three normal female non-smokers, 268 normal male non-smokers, and 224 normal male smokers were included in our comparative study to determine possible effect of smoking on the serum levels of cytokeratin fragment 19 (CYFRA 21-1). Immunoradiometric assay (IRMA) was used, and the results revealed that the mean +/- SD CYFRA 21-1 levels in the 293 normal female non-smokers, 268 normal male non-smokers, and 224 normal male smokers were 1.28 +/- 0.82, 1.38 +/- 0.74, and 1.47 +/- 0.62 ng/ml, respectively. There is no significantly statistical difference in the CYFRA 21-1 level among the three groups. In conclusion, we suggest that smoking has no effect on the serum levels of CYFRA 21-1.
Kao
C H
CH
Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan.
Hsieh
J F
JF
Ho
Y J
YJ
Tsai
S C
SC
Lee
J K
JK
D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D005260:Female; D006304:Health Status; D006801:Humans; D053539:Keratin-19; D007633:Keratins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012907:Smoking / Q000097:blood*
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D053539:Keratin-19; C102012:antigen CYFRA21.1; D007633:Keratins