title: Anterior reconstructive spinal surgery with Zielke instrumentation for metastatic malignancies of the spine.
abstract: From March 1984 to April 1996, 60 consecutive patients with spinal metastasis underwent palliative surgery by anterior corpectomy and Zielke instrumentation. Their ages ranged from 21 to 76 years (mean 54 years). Thirty-two patients had metastasis to the thoracic spine, 20 to the lumbar spine, and 8 had both thoracic and lumbar metastases. The primary malignancies were lung cancer in 12 patients, colorectal cancer in 10, hepatoma in 9, thyroid cancer in 7, breast cancer in 3, and cancers of the stomach, kidney, nasopharynx, long bones, skin, and cervix in 1 patient each. A primary carcinoma was never identified in 13 patients. In the present series, 4 patients died within 1 month, and 56 patients were followed-up. All maintained spinal stability postoperatively. Forty of 52 patients with severe pain obtained significant symptomatic relief for 3 months or more, and 33 of the 46 paralyzed patients gained neural improvement. Sphincter dysfunction became better in 10 patients, and none became worse. We conclude that anterior corpectomy to decompress neural encroachment with instrumental reconstruction to stabilize the collapsed spine is a good adjunctive treatment in these highly selected patients.
authors.affiliation: Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan.
authors.forename: L H
authors.initials: LH
authors.lastname: Chen
authors.forename: W J
authors.initials: WJ
authors.lastname: Chen
authors.forename: C C
authors.initials: CC
authors.lastname: Niu
authors.forename: C H
authors.initials: CH
authors.lastname: Shih
mesh_terms: D000328:Adult; D000368:Aged; D019299:Decompression, Surgical / Q000295:instrumentation*; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D013125:Spinal Neoplasms / Q000556:secondary* / Q000601:surgery*; D013904:Thoracic Vertebrae