A bird's eye view of global methylation.
Restriction landmark genomic scanning applied to a broad variety of cancer types can disclose tumour-specific and tumour-type-specific global methylation profiles. This and other genome-scanning approaches allows the rapid analysis of methylation profiles of thousands of genes in parallel-and promises to identify new genes critical to carcinogenesis and other biological processes.
Eng
C
C
Herman
J G
JG
Baylin
S B
SB
D019175:DNA Methylation; D016147:Genes, Tumor Suppressor; D018095:Germ-Line Mutation; D006801:Humans; D009154:Mutation; D009369:Neoplasms / Q000235:genetics*; D015183:Restriction Mapping