title: Laparoscopic fundoplication for gastro-oesophageal reflux disease - a consensus development conference and the evidence-based benefit.
abstract: The aim of this paper is to demonstrate an example of evidence-based medicine for a clinically relevant and frequent disease - gastro-oesophageal reflux disease - for which an increasing number of laparoscopic operations is performed. A consensus development conference was performed on this topic in 1996. During the following 3-year period, increase of knowledge shown by the number of publications was monitored and the consecutive changes of the consensus as well as its consequences and impact were analysed. The six published randomised clinical trials revealed important information about the technique of the laparoscopic operation focussing on the gastric fundic mobilisation and the modification of the anti-reflux wrap. Five consecutive consensus conferences were performed and published. Citations of the 1996 consensus conference could not be found in the major surgical journals - not even by participants of the conference. The responsibility of societies to run such conferences continues.
authors.affiliation: Chirurgische Klinik, St.Hildegardis-Krankenhaus Köln-Lindenthal, Bachemer Strasse 29-31, D-50931 Köln, Germany. eypasch@netcologne.de
authors.forename: E
authors.initials: E
authors.lastname: Eypasch
authors.forename: B
authors.initials: B
authors.lastname: Thiel
authors.forename: S
authors.initials: S
authors.lastname: Sauerland
mesh_terms: D003245:Consensus Statements as Topic; D003362:Cost-Benefit Analysis; D019468:Disease Management; D005060:Europe; D019317:Evidence-Based Medicine / Q000379:methods*; D018662:Fundoplication / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D012955:Societies, Medical