Acute chest syndrome in sickle cell disease. Crucial considerations in adolescents and adults.
Rapid recognition of acute chest syndrome is essential in patients with sickle cell disease. The condition can be particularly severe in adolescents and adults and often leads to death. In this article, the authors review the challenges of evaluating the syndrome and outline current treatment and supportive care.
Yale
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Marshfield Clinic, Department of Internal Medicine, WI 54449, USA. yales@mfldclin.edu
Nagib
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Guthrie
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D000293:Adolescent; D000328:Adult; D006801:Humans; D007040:Hypoventilation / Q000209:etiology*; D000860:Hypoxia / Q000209:etiology*; D012307:Risk Factors; D012805:Sickle Cell Trait / Q000150:complications*; D013147:Spirometry; D013577:Syndrome