Crossed cerebellocerebral diaschisis in patients with cerebellar stroke.
OBJECTIVE
We performed single-photon emission computed tomography (SPECT) to investigate crossed cerebellocerebral diaschisis (CCCD) in patients with cerebellar stroke.


METHODS
Fifteen patients with unilateral cerebellar stroke underwent SPECT of the brain with N-isopropyl-p-[123I] iodoamphetamine (123I-IMP). Regional cerebral blood flow (rCBF) was measured by the autoradiographic method. Regions of interest were defined in the cerebral cortex, striatum, thalamus and cerebellum to compare structures (contralateral to the cerebellar lesion) with counterparts ipsilateral to the stroke.


RESULTS
In the frontal and parietal cortices, especially the posterior superior frontal, anterior midfrontal, precentral, postcentral, and supramarginal areas, rCBF contralateral to the lesion was significantly lower than on the side of the lesion (showing CCCD).


CONCLUSIONS
This CCCD phenomenon is important to be aware of in clinical reading of images.
Komaba
Y
Y
Second Department of Internal Medicine, Nippon Medical School, Tokyo, Japan.
Osono
E
E
Kitamura
S
S
Katayama
Y
Y
D000368:Aged; D000369:Aged, 80 and over; D001931:Brain Mapping; D002531:Cerebellum / Q000098:blood supply*; D002540:Cerebral Cortex / Q000098:blood supply* / Q000000981:diagnostic imaging; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000503:physiopathology; D002544:Cerebral Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003342:Corpus Striatum / Q000098:blood supply / Q000000981:diagnostic imaging; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009434:Neural Pathways / Q000098:blood supply / Q000000981:diagnostic imaging; D012039:Regional Blood Flow / Q000502:physiology; D013788:Thalamus / Q000098:blood supply / Q000000981:diagnostic imaging; D015899:Tomography, Emission-Computed, Single-Photon