title: Nanophthalmic uveal effusion syndrome after prophylactic laser treatment.
abstract: OBJECTIVE
  We report a case of nanophthalmic uveal effusion syndrome (NUES) with total exudative retinal detachment (RD) after prophylactic argon laser (AL) treatment. The RD subsided and eventually resolved with i.v. steroid therapy.
  
  
  METHODS
  A 45-year-old woman was referred to us with NUES and total exudative RD after prophylactic AL treatment for retinoschisis performed elsewhere. The patient had been scheduled for surgical intervention and was given i.v. prednisolone.
  
  
  RESULTS
  Two days after starting i.v. prednisolone, the subretinal fluid partially resolved. Intervention had therefore been postponed. After 15 days the RD almost disappeared and vision improved to 20/400. Ten days later the macula was flat and vision was 20/200. At the six-month follow-up visit vision was 20/40.
  
  
  CONCLUSIONS
  To our knowledge this is the first report of NUES and total exudative RD following AL treatment that resolved with i.v. steroid therapy alone. Since the AL treatment clearly seemed to play a role in the pathogenesis of the NUES and associated RD we strongly advise careful assessment of the risk/benefit ratio of prophylactic laser treatment in nanophthalmic patients. Although sclerectomy and vortex vein decompression are well-established techniques, we believe steroid therapy might be tried before proceeding to surgery.
authors.affiliation: Surgical Retina Service, Roma Trauma Hospital, Ospedale CTO-USL Roma C, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Lesnoni
authors.forename: T
authors.initials: T
authors.lastname: Rossi
authors.forename: A
authors.initials: A
authors.lastname: Nistri
authors.forename: B
authors.initials: B
authors.lastname: Boccassini
mesh_terms: D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects*; D008266:Macula Lutea / Q000473:pathology; D008850:Microphthalmos / Q000209:etiology*; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use*; D012163:Retinal Detachment / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D015866:Uveitis, Posterior / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology
chemical_list: D011239:Prednisolone