Presence of type III secretion genes in Burkholderia pseudomallei correlates with Ara(-) phenotypes.
Dot blot hybridization and PCR amplification of 14 Ara(+) and 8 Ara(-) Burkholderia pseudomallei strains showed that type III secretion (TTS) genes were present in all the Ara(-) strains but absent from all but one of the Ara(+) strains. The link between TTS genes and an Ara(-) phenotype suggests a role for TTS in virulence.
Winstanley
C
C
Department of Medical Microbiology and Genito-Urinary Medicine, University of Liverpool, Liverpool L69 3GA, United Kingdom. C.Winstanley@liverpool.ac.uk
Hart
C A
CA
D000818:Animals; D001089:Arabinose / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D016957:Burkholderia pseudomallei / Q000235:genetics* / Q000378:metabolism / Q000472:pathogenicity*; D004269:DNA, Bacterial / Q000032:analysis; D004783:Environmental Microbiology; D005798:Genes, Bacterial; D006801:Humans; D008554:Melioidosis / Q000382:microbiology; D009693:Nucleic Acid Hybridization; D010641:Phenotype; D016133:Polymerase Chain Reaction
D001426:Bacterial Proteins; D004269:DNA, Bacterial; D001089:Arabinose