title: Helical and single-slice conventional CT versus electron beam CT for the quantification of coronary artery calcification.
abstract: OBJECTIVE
  We compared electron beam CT with conventional CT to determine the best method for the assessment of the coronary calcium score. We used conventional CT to examine symptomatic and asymptomatic patients suspected of having coronary artery disease.
  
  
  METHODS
  One hundred sixty male patients underwent electron beam CT and helical CT with a pitch of 1 (n = 30) and 2 (n = 30) and using a single-slice mode with (n = 50) and without (n = 50) prospective ECG triggering. In another 50 patients, we determined reproducibility for repeated scanning using electron beam CT. For all images, we derived the calcium score according to the Agatston method. We performed regression analysis and determined mean variability. Mean variability was calculated as the ratio of the absolute difference to the mean of the corresponding calcium scores.
  
  
  RESULTS
  The correlation coefficients for electron beam CT and all conventional CT modes were very high (range, 0.93-0.98). The mean variability was highest in the helical mode with a pitch of 2 (61.4%) and lowest for the single-slice mode with prospective ECG triggering (25.4%). For repeated electron beam CT, the correlation coefficient and mean variability were 0.99 and 22.1%, respectively.
  
  
  CONCLUSIONS
  ECG-triggered single-slice conventional CT had the best agreement with electron beam CT calcium scores.
authors.affiliation: Department of Diagnostic Radiology, Ludwig-Maximilians-University, Klinikum Grosshadern, Munich, Germany.
authors.forename: C R
authors.initials: CR
authors.lastname: Becker
authors.forename: T F
authors.initials: TF
authors.lastname: Jakobs
authors.forename: S
authors.initials: S
authors.lastname: Aydemir
authors.forename: A
authors.initials: A
authors.lastname: Becker
authors.forename: A
authors.initials: A
authors.lastname: Knez
authors.forename: U J
authors.initials: UJ
authors.lastname: Schoepf
authors.forename: R
authors.initials: R
authors.lastname: Bruening
authors.forename: R
authors.initials: R
authors.lastname: Haberl
authors.forename: M F
authors.initials: MF
authors.lastname: Reiser
mesh_terms: D002114:Calcinosis / Q000000981:diagnostic imaging*; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D004583:Electrons; D006801:Humans; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods*