title: Structural determinants of efficacy for kappa opioid receptors in the orvinol series: 7,7-spiro analogues of buprenorphine.
authors.affiliation: School of Chemistry, Cantock's Close, University of Bristol, Bristol, England.
authors.forename: S M
authors.initials: SM
authors.lastname: Husbands
authors.forename: J W
authors.initials: JW
authors.lastname: Lewis
mesh_terms: D000701:Analgesics, Opioid / Q000494:pharmacology*; D000818:Animals; D002047:Buprenorphine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D016466:CHO Cells; D006224:Cricetinae; D015394:Molecular Structure; D017473:Receptors, Opioid, kappa / Q000187:drug effects*
chemical_list: D000701:Analgesics, Opioid; D017473:Receptors, Opioid, kappa; D002047:Buprenorphine