title: Corrosion and cytotoxicity evaluation of thermafil endodontic obturator carriers.
abstract: The purpose of this study was to evaluate the in vitro cytotoxicity of two metallic and two plastic Thermafil carrier materials, and to separately evaluate the in vitro corrosion behavior of the two metallic carriers. Stainless-steel, Ti-6AI-4V, Polysulfone, and Vectra carriers were evaluated for cytotoxicity using the ISO-recommended agar overlay test. The two metallic carriers were additionally corrosion tested in 0.9% NaCl solution for 174 wk, at 37 degrees C. Elemental analyses of the corrosion solutions were periodically conducted using inductively coupled plasma-mass spectroscopy. Agar overlay results showed that the four carrier materials were not cytotoxic to L929 fibroblasts. Inductively coupled plasma-mass spectroscopy results showed that the metallic materials had small mass loss rates. Scanning electron microscopy showed no evidence of pitting or crevice corrosion.
authors.affiliation: Faculty of Dentistry, Dalhousie University, Halifax, Nova Scotia, Canada.
authors.forename: E J
authors.initials: EJ
authors.lastname: Sutow
authors.forename: W C
authors.initials: WC
authors.lastname: Foong
authors.forename: K L
authors.initials: KL
authors.lastname: Zakariasen
authors.forename: G C
authors.initials: GC
authors.lastname: Hall
authors.forename: D W
authors.initials: DW
authors.lastname: Jones
mesh_terms: D000497:Alloys; D000818:Animals; D001672:Biocompatible Materials / Q000633:toxicity*; D003343:Corrosion; D004337:Drug Carriers / Q000737:chemistry / Q000633:toxicity*; D007739:L Cells / Q000187:drug effects; D013058:Mass Spectrometry / Q000379:methods; D051379:Mice; D010969:Plastics / Q000633:toxicity; D012389:Root Canal Obturation / Q000295:instrumentation*; D013193:Stainless Steel / Q000737:chemistry / Q000633:toxicity; D013450:Sulfones / Q000633:toxicity; D014025:Titanium / Q000737:chemistry / Q000633:toxicity; D018675:Toxicity Tests
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; D004337:Drug Carriers; D010969:Plastics; D013450:Sulfones; D013193:Stainless Steel; C031462:titanium alloy (TiAl6V4); D014025:Titanium