Positive and negative outcomes of L-arginine therapy in cardiovascular diseases.
The author reviews controlled clinical investigation on the effectiveness of L-arginine in cardiovascular diseases. Positive results were observed in hyperlipidemic subjects and in patients with a critical stage of the peripheral arterial occlusive disease. Patients with stable ischemic heart disease responded to L-arginine to some extent, while results of L-arginine therapy in congestive heart failure are inconsistent. Null effects if L-arginine has been documented in essential hypertension.
Herbaczyńska-Cedro
K
K
Cardiovascular Laboratory, Research Centre of Experimental & Clinical Medicine, Polish Academy of Sciences, Warsaw.
D001120:Arginine / Q000627:therapeutic use*; D001157:Arterial Occlusive Diseases / Q000188:drug therapy*; D002318:Cardiovascular Diseases / Q000188:drug therapy*; D018849:Controlled Clinical Trials as Topic; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D006949:Hyperlipidemias / Q000188:drug therapy; D017202:Myocardial Ischemia / Q000188:drug therapy; D009569:Nitric Oxide / Q000096:biosynthesis / Q000502:physiology; D016896:Treatment Outcome
D009569:Nitric Oxide; D001120:Arginine