Epidemic typhoid in vietnam: molecular typing of multiple-antibiotic-resistant Salmonella enterica serotype typhi from four outbreaks.
Multidrug-resistant Salmonella enterica serotype Typhi isolates from four outbreaks of typhoid fever in southern Vietnam between 1993 and 1997 were compared. Pulsed-field gel electrophoresis, bacteriophage and plasmid typing, and antibiotic susceptibilities showed that independent outbreaks of multidrug-resistant typhoid fever in southern Vietnam are caused by single bacterial strains. However, different outbreaks do not derive from the clonal expansion of a single multidrug-resistant serotype Typhi strain.
Connerton
P
P
The Department of Biochemistry, Imperial College of Science, Technology and Medicine, London SW7 2AZ, United Kingdom.
Wain
J
J
Hien
T T
TT
Ali
T
T
Parry
C
C
Chinh
N T
NT
Vinh
H
H
Ho
V A
VA
Diep
T S
TS
Day
N P
NP
White
N J
NJ
Dougan
G
G
Farrar
J J
JJ
D015373:Bacterial Typing Techniques; D004196:Disease Outbreaks; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D012485:Salmonella typhi / Q000145:classification / Q000187:drug effects / Q000235:genetics; D014435:Typhoid Fever / Q000453:epidemiology* / Q000382:microbiology*; D014744:Vietnam / Q000453:epidemiology