title: Should we establish chest pain observation units in the UK? A systematic review and critical appraisal of the literature.
abstract: OBJECTIVE
  The chest pain observation unit (CPOU) has been developed in the United States to allow rigorous assessment of patients presenting with chest pain, thus expediting their discharge if assessment is negative. This review aims to examine the evidence for effectiveness and economic efficiency of the CPOU and to explore whether data from the United States can be extrapolated to the UK.
  
  
  METHODS
  Search of the literature using Medline and critical appraisal of the validity of the data.
  
  
  RESULTS
  Five studies comparing outcomes of CPOU care with routine practice showed no significant difference in objective measures including mortality or missed pathology. Eleven studies described outcomes of a cohort of CPOU patients. Follow up was comprehensive and demonstrated no clinically significant evidence of missed pathology. Nine studies comparing CPOU costs with routine care demonstrated impressive cost savings that were more modest when randomised comparisons were made.
  
  
  CONCLUSIONS
  CPOU care is safe and costs are well defined. There is no strong evidence that a CPOU will improve outcomes if routine practice is good. Cost savings have been shown when compared with routine care in the United States but may not be reproduced the UK.
authors.affiliation: Accident and Emergency Department, Northern General Hospital, Sheffield. steveg@doctors.org.uk
authors.forename: S W
authors.initials: SW
authors.lastname: Goodacre
mesh_terms: D002637:Chest Pain / Q000175:diagnosis* / Q000209:etiology*; D017046:Cost Savings; D003362:Cost-Benefit Analysis; D017598:Efficiency, Organizational; D004636:Emergency Service, Hospital / Q000458:organization & administration*; D006302:Health Services Research; D006801:Humans; D009203:Myocardial Infarction / Q000150:complications* / Q000175:diagnosis*; D020380:Needs Assessment / Q000458:organization & administration; D019370:Observation; D017063:Outcome Assessment, Health Care; D018710:Pain Clinics / Q000458:organization & administration*; D012107:Research Design; D006113:United Kingdom; D014481:United States; D016526:Workload