[CD30-positive anaplastic large cell lymphoma of bone treated with autologous peripheral blood stem cell transplantation].
A 30-year-old man was admitted to our hospital with the chief complaints of fever and pain in the right shoulder, axilla, and inguinocrural region. Computed tomography, magnetic resonance imaging, 67Ga-scintigraphy, and bone-scintigraphy revealed osteolytic lesions in the ribs and right ilium. Biopsy specimens from lesions in the right ilium confirmed the diagnosis of CD 30-positive anaplastic large cell lymphoma. The patient was treated with 6 courses of CHOP therapy followed by high-dose chemotherapy and autologous peripheral blood stem cell transplantation. He achieved and remained in remission with no evidence of relapse 14 months later.
Bohgaki
T
T
Department of Clinical Immunology and Hematology, Sapporo City General Hospital.
Notoya
A
A
Mukai
M
M
Kohno
M
M
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis*; D001859:Bone Neoplasms / Q000175:diagnosis / Q000628:therapy*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D003952:Diagnostic Imaging; D004317:Doxorubicin / Q000008:administration & dosage; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D017730:Ki-1 Antigen / Q000032:analysis*; D017728:Lymphoma, Large-Cell, Anaplastic / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage; D012074:Remission Induction; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014750:Vincristine / Q000008:administration & dosage
D014408:Biomarkers, Tumor; D017730:Ki-1 Antigen; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone