Basilar invagination as a sequela of multisystem Langerhans' cell histiocytosis.
We report the presence of basilar invagination, an unexpected and previously undescribed abnormality of the skull base, in 7 of 38 long-term survivors of multisystem Langerhans' cell histiocytosis. The abnormality is acquired, but its pathogenesis is uncertain.
Nanduri
V R
VR
Department of Haematology/Oncology, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom.
Jarosz
J M
JM
Levitt
G
G
Stanhope
R
R
Chong
W K
WK
Pritchard
J
J
D000293:Adolescent; D000328:Adult; D001847:Bone Diseases / Q000209:etiology*; D002526:Cerebellar Diseases / Q000209:etiology; D002648:Child; D015331:Cohort Studies; D004677:Encephalocele / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D005539:Foramen Magnum / Q000473:pathology; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications*; D006801:Humans; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D008297:Male; D009777:Occipital Bone / Q000473:pathology*; D009809:Odontoid Process / Q000473:pathology; D010985:Platybasia / Q000209:etiology; D017741:Survivors