title: Effect of ammonium and nitrate ratio on glucose oxidase activity during gluconic acid fermentation by a mutant strain of Aspergillus niger.
abstract: Of the factors tested, the source and concentration of carbon and nitrogen in the medium exerted maximum effect on growth and acid production. Glucose (15%) and urea (0.14%) induced glucose oxidase synthesis and optimum yield of calcium gluconate. Potassium dihydrogen phosphate (0.2%) and magnesium sulphate (0.06%) stimulated glucose oxidase activity and calcium gluconate production. Borax at a concentration of 1.5 g/L induced maximum glucose oxidase and calcium gluconate production with increased glucose utilization.
authors.affiliation: Department of Chemical Engineering, University of Calcutta, India.
authors.forename: S
authors.initials: S
authors.lastname: Ray
authors.forename: A K
authors.initials: AK
authors.lastname: Banik
mesh_terms: D001234:Aspergillus niger / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D001709:Biotechnology; D005285:Fermentation; D005942:Gluconates / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D005949:Glucose Oxidase / Q000378:metabolism*; D009154:Mutation; D009566:Nitrates / Q000378:metabolism / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds / Q000378:metabolism / Q000494:pharmacology
chemical_list: D005942:Gluconates; D009566:Nitrates; D000644:Quaternary Ammonium Compounds; D005949:Glucose Oxidase; D005947:Glucose; C030691:gluconic acid