How centrioles work: lessons from green yeast.
Centrioles are the organizing centers around which centrosomes assemble. Despite a century of study, the molecular details of centriole function and assembly remain largely unknown. Recent work has exploited the unique advantages of unicellular algae to reveal proteins that play central roles in centriole biology.
Marshall
W F
WF
Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA. wallace.marshall@yale.edu
Rosenbaum
J L
JL
D000818:Animals; D002502:Centrioles / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D002696:Chlamydomonas / Q000166:cytology* / Q000235:genetics; D008870:Microtubules / Q000235:genetics / Q000378:metabolism; D008941:Spindle Apparatus / Q000378:metabolism