title: Magnetic resonance findings in amyotrophic lateral sclerosis using a spin echo magnetization transfer sequence. Preliminary report.
abstract: We present the magnetic resonance (MR) findings of five patients with amyotrophic lateral sclerosis (ALS) using a spin-echo sequence with an additional magnetization transfer (MT) pulse on T1-weighted images (T1 SE/MT). These findings were absent in the control group and consisted of hyperintensity of the corticospinal tract. Moreover we discuss the principles and the use of this fast but simple MR technique in the diagnosis of ALS.
authors.affiliation: Serviço de Diagnóstico por Imagem da Santa Casa de Misericórdia de São Paulo, Brasil. a.rocha@uol.com.br
authors.forename: A J
authors.initials: AJ
authors.lastname: da Rocha
authors.forename: A C
authors.initials: AC
authors.lastname: Maia
authors.forename: R G
authors.initials: RG
authors.lastname: Nogueira
authors.forename: H M
authors.initials: HM
authors.lastname: Lederman
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D011712:Pyramidal Tracts / Q000473:pathology*