[Ca(2+) level in the animal blood and their cold resistance].
Administration of small doses of the EDTA decreased by 15-20% the Ca2+ contentn in the blood plasma of rabbits and rats. The decrease coincided with an abrupt stimulation of the thermoregulation system of cooled animals. Restoration of the Ca2+ content in circulating blood coincided in time with repeated suppression of the system's functions. The findings corroborate the theory of a key role of the Ca2+ in sensitivity of the homoiothermal organism to cold and substantiates the method of restoring physiological functions in deep hypothermia without rewarming the body.
Ivanov
K P
KP
I. P. Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg, Russia.
Arokina
N K
NK
Didina
S E
SE
Volkova
M F
MF
D000818:Animals; D001775:Blood Circulation; D001833:Body Temperature Regulation / Q000187:drug effects / Q000502:physiology*; D002118:Calcium / Q000097:blood*; D002614:Chelating Agents / Q000494:pharmacology; D003080:Cold Temperature; D004492:Edetic Acid / Q000494:pharmacology; D008297:Male; D008839:Microelectrodes; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar
D002614:Chelating Agents; D004492:Edetic Acid; D002118:Calcium