title: Antiplatelet and anticoagulant therapy in the secondary prevention of ischemic heart disease.
abstract: Antiplatelet and anticoagulant medications play a major role in the secondary prevention of ischemic heart disease. Numerous trials have demonstrated their clinical benefits. Newer agents, such as clopidogrel, have challenged aspirin's role as the premier medication for secondary prevention. Much remains to be learned, however, about the merits of these different drug classes, relative to one another and in combination.
authors.affiliation: Department of Cardiology, Cleveland Clinic Foundation, Ohio, USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Bhatt
authors.forename: E J
authors.initials: EJ
authors.lastname: Topol
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage* / Q000009:adverse effects; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects; D000077144:Clopidogrel; D003327:Coronary Disease / Q000517:prevention & control*; D006801:Humans; D009203:Myocardial Infarction / Q000517:prevention & control*; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage* / Q000009:adverse effects; D012008:Recurrence; D013988:Ticlopidine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin