title: Statistical problems with 'optimal' thresholds in studies of new prognostic factors in urology.
authors.affiliation: Department of Surgery, Cancer Research Unit, University of Newcastle upon Tyne, UK.
authors.forename: P E
authors.initials: PE
authors.lastname: Keegan
authors.forename: J N
authors.initials: JN
authors.lastname: Matthews
authors.forename: J
authors.initials: J
authors.lastname: Lunec
authors.forename: D E
authors.initials: DE
authors.lastname: Neal
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D011237:Predictive Value of Tests; D011379:Prognosis; D012372:ROC Curve; D018570:Risk Assessment; D014571:Urologic Neoplasms / Q000175:diagnosis* / Q000401:mortality
chemical_list: D014408:Biomarkers, Tumor