Outcome in recipients of dual kidney transplants: an analysis of the dual registry patients.
BACKGROUND
A novel but controversial method to increase the utilization of aged donor kidneys is the transplantation of both kidneys as a dual transplant. Initial single-center reports demonstrated outcomes similar to single kidneys from younger donors. In this report, we compare outcome in recipients of kidneys from donors > or =54 years of age who received a single kidney transplant reported to the United Network for Organ Sharing Scientific Registry versus a dual kidney transplant reported to the Dual Kidney Registry.


METHODS
A retrospective analysis was performed, comparing four donor and nine recipient and outcome variables between recipients of a single versus a dual transplant between March 1993 and March 1999.


RESULTS
Dual versus single transplants from donors > or =54 years of age have a significantly decreased incidence of delayed graft function, and lower serum creatinines up to 2 years after transplant despite having kidneys from significantly older donors with poorer HLA matching.


CONCLUSIONS
Dual kidney transplants improve graft performance and outcome in recipients of kidneys from donors > or =54 years of age.
Lu
A D
AD
Department of Surgery, Stanford University, California 94305, USA.
Carter
J T
JT
Weinstein
R J
RJ
Stratta
R J
RJ
Taylor
R J
RJ
Bowers
V D
VD
Ratner
L E
LE
Chavin
K D
KD
Johnson
L B
LB
Kuo
P C
PC
Cole
E H
EH
Dafoe
D C
DC
Alfrey
E J
EJ
D000368:Aged; D006801:Humans; D016030:Kidney Transplantation / Q000379:methods / Q000502:physiology; D008875:Middle Aged; D012042:Registries; D014019:Tissue Donors; D016896:Treatment Outcome