Androgen-producing ovarian tumors: a clinicopathological study of 3 cases.
The clinical course and pathological findings of 3 rare cases of androgen-producing ovarian tumors are presented. The ages of the 3 patients (Cases 1, 2, and 3, respectively) were 43, 34, and 57 years, respectively. Their preoperative serum testosterone levels were 506, 491, and 231 ng/dl, respectively. The pathological diagnoses of Cases 1, 2, and 3 were a Sertoli-stromal cell tumor of intermediate differentiation, a stromal tumor containing Leydig cells, and a stromal tumor with minor sex cord elements, respectively. Patient 1 experienced a recurrence, of a lesion at the vaginal stump 1 year and 2 months after the initial surgery. The clinical courses of Cases 2 and 3 have been non-contributory.
Arai
M
M
Department of Obstetrics and Gynecology, School of Medicine, Kitasato University, Kanagawa, Japan.
Jobo
T
T
Iwaya
H
H
Sato
R
R
Watanabe
J
J
Ohno
E
E
Kuramoto
H
H
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007984:Leydig Cell Tumor / Q000097:blood / Q000473:pathology*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood / Q000473:pathology*; D012707:Sertoli Cell Tumor / Q000097:blood / Q000473:pathology*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000097:blood / Q000473:pathology*; D013739:Testosterone / Q000097:blood
D013739:Testosterone