title: INAA of serum zinc of inhabitants in five regions of the Czech Republic.
abstract: To investigate the Zn status of inhabitants of the Czech Republic, 1155 serum and 132 hair samples were analyzed for zinc content. Analyzed material was obtained from randomly selected volunteers of both sexes in the age range 6-65 yr. Subpopulations from five regions were included in the study. Analyses of both materials were performed by Instrumental Neutron Activation Analysis (INAA). Coanalyses of Standard Reference Materials (SRM) for quality control were performed. The results (mean 910 +/- 276 micrograms Zn/L serum and 189 +/- 45 micrograms Zn/g hair) demonstrate satisfactory zinc status of the searched population. Significant interregional differences and age-dependent differences, as well as sex-dependent differences have been detected by the use of correlation analysis. On the basis of these results, serum Zn concentration results of individual categories according to age and sex were evaluated, and on the grounds of mean +/- 2 standard deviations, indicative intervals were calculated. The frequency of individual serum Zn concentrations proved that the population of the Czech Republic does not suffer from severe zinc deficiency. On the other hand, about one-third of our inhabitants has their serum Zn concentrations below the cutoff value of 800 micrograms Zn/L serum, which means a marginal or mild Zn deficit of the organism.
authors.affiliation: Institute of Endocrinology, Prague, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Kvicala
authors.forename: V
authors.initials: V
authors.lastname: Jiránek
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D018153:Czech Republic; D005260:Female; D006197:Hair / Q000737:chemistry; D006801:Humans; D008297:Male; D008875:Middle Aged; D009501:Neutron Activation Analysis; D011159:Population Surveillance; D015032:Zinc / Q000032:analysis / Q000097:blood* / Q000172:deficiency
chemical_list: D015032:Zinc