[Distribution and features of infection with hepatitis viruses B and C during hemodialysis treatment].
The prevalence of hepatitides B and C was evaluated in 140 patients treated by hemodialysis. Almost half of patients (48%) had acute hepatitis B which completely resolved. Acute hepatitis B was detected in 6% in the course of observation. In 6% chronic hepatitis B was diagnosed, and in 24% chronic hepatitis C. A combination of hepatitides B and C was diagnosed in 2% patients. Only 12% patients were not infected with hepatitis. Genotype 1b predominated in patients with HCV infection (73%); genotypes 1a, 21, and 3a were equally incident (9%). Replication of HBV and HCV in patients with uremia under conditions of hemodialysis was detected in 83 and 86% patients, respectively. Relationship between HBV and HCV infection and the duration of hemodialysis treatment was analyzed. The percentage of non-infected patients persistently decreased, and the time course of HBV and HCV infection was different. Infection with HBV after the beginning of hemodialysis occurred sooner (16.0 +/- 4.0 months) than with HCV (30.2 +/- 4.6 months, p < 0.04). The levels of SGPT and SGOT in patients with various manifestations of HBV and HCV infection treated by hemodialysis were followed up.
Zubkin
M L
ML
Selivanov
N A
NA
Stakhanova
V M
VM
Novozhenov
V G
VG
Sel'kova
E P
EP
Kucherova
T E
TE
Baranova
F S
FS
Kozhokar'
Iu V
IuV
Kirkhman
V V
VV
Kasapova
E N
EN
Stenina
I I
II
L'vov
D K
DK
D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D005838:Genotype; D016174:Hepacivirus / Q000235:genetics; D006509:Hepatitis B / Q000201:enzymology / Q000453:epidemiology* / Q000635:transmission; D006526:Hepatitis C / Q000201:enzymology / Q000453:epidemiology* / Q000635:transmission; D006801:Humans; D015995:Prevalence; D006435:Renal Dialysis / Q000009:adverse effects*
D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase