Study on pathogenic mechanism of emotions in traditional Chinese medicine--an observation of hydrogen peroxide releasing function of celiac macrophages in rats under stress state.
The hydrogen peroxide releasing function of macrophages in rats under the stress state was observed with the animal model of "excessive anger impairing the liver". The results showed that the volume of hydrogen peroxide released from the macrophages in rats was decreased, while the corticosterone level in plasma increased after stress. It indicates that stimulation of harmful emotions could cause inhibition of immunoreaction of the organism, which might be related to the enhancement in excitability of the hypothalamus-pituitary-adrenal axis and hypersecretion of glucocorticoid hormone.
Yan
C
C
Department of Basic Theories of Traditional Chinese Medicine, Guangzhou University of Traditional Chinese Medicine and Pharmacy, Guangdong Province.
Pan
Y
Y
Wu
L
L
Deng
Z
Z
Gao
M
M
D000818:Animals; D003345:Corticosterone / Q000097:blood; D006861:Hydrogen Peroxide / Q000378:metabolism*; D008264:Macrophages / Q000378:metabolism*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013312:Stress, Physiological / Q000276:immunology* / Q000378:metabolism
D006861:Hydrogen Peroxide; D003345:Corticosterone