[Effects of mild hypothermia on Na(+)-K+ ATPase and lipid peroxidation in canine brain tissue following cardiac arrest and resuscitation].
The effect of mild hypothermia on Na(+)-K+ ATPase and lipid peroxidation in canine brain tissue following a 18-minute cardiac arrest and resuscitation for 8 hours were studied. Mild hypothermia improved the restoration of the activity of Na(+)-K+ ATPase, LDH, protect the activity of SOD, decrease the loss of GSH, but not completely blocked the ischemia reperfusion induced lipid peroxidation.
Wang
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Y
Department of Anesthesiology, Xiangya Hospital, Hunan Medical University, Changsha.
Tan
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X
Cai
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H
D000818:Animals; D001921:Brain / Q000201:enzymology* / Q000378:metabolism; D002545:Brain Ischemia / Q000201:enzymology* / Q000378:metabolism; D016887:Cardiopulmonary Resuscitation; D004285:Dogs; D006324:Heart Arrest, Induced; D007036:Hypothermia, Induced; D015227:Lipid Peroxidation; D015427:Reperfusion Injury / Q000201:enzymology / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism*
D013482:Superoxide Dismutase; D000254:Sodium-Potassium-Exchanging ATPase