Frequency and Markov chain analysis of amino-acid sequences of human glutathione reductase.
The amino-acid sequence of human glutathione reductase was measured according to two- and three-amino-acid sequences. The measured frequency and probability were compared with predicted frequency and probability. Of 477 two-amino-acid sequences in human glutathione reductase, 176 (36.897%) and 90 (18.868%) sequences can be explained by the predicted frequency and the predicted probability according to a purely random mechanism. Of 477 measured first Markov transition probabilities for the second amino acid in two-amino-acid sequences, 1 (0.210%) measured first Markov transition probability matches the predicted conditional probability and can therefore be explained by a purely random mechanism. No more than two-amino-acid sequences can be explained by a purely random mechanism.
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Advanced Course on "Cytokines in Immunity", University of Naples, Naples, Italy.
D000595:Amino Acid Sequence; D004151:Dipeptides / Q000737:chemistry; D005980:Glutathione Reductase / Q000737:chemistry* / Q000235:genetics; D006801:Humans; D008390:Markov Chains; D008956:Models, Chemical; D009842:Oligopeptides / Q000737:chemistry
D004151:Dipeptides; D009842:Oligopeptides; D005980:Glutathione Reductase