Uterine rupture in a multiparous woman during labor induction with oral misoprostol.
A multigravida with gestational diabetes, mild pregnancy-induced hypertension and a previous curettage received four doses of misoprostol (100 microg) at three hourly intervals for induction of labor at term. Vaginal delivery of a live healthy baby occurred 1 h after the fourth dose. Hindwaters were bloodstained. Three hours later, she had excessive bleeding. Examination showed that the left lateral uterine wall had ruptured. She recovered after hysterectomy and blood transfusions.
Mathews
J E
JE
Department of Obstetrics & Gynecology, Christian Medical College Hospital, Vellore, India.
Mathai
M
M
George
A
A
D000284:Administration, Oral; D016640:Diabetes, Gestational; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007751:Labor, Induced; D016595:Misoprostol / Q000008:administration & dosage / Q000009:adverse effects*; D010120:Oxytocics / Q000008:administration & dosage / Q000009:adverse effects*; D010298:Parity; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular; D012307:Risk Factors; D014597:Uterine Rupture / Q000139:chemically induced*
D010120:Oxytocics; D016595:Misoprostol