Protective effect of L-carnitine in the neurotoxicity induced by the mitochondrial inhibitor 3-nitropropionic acid (3-NPA).
Binienda
Z
Z
Division of Neurotoxicology, National Center for Toxicological Research/Food and Drug Administration (NCTR/FDA), Jefferson, Arkansas 72079-9502, USA. zbinienda@nctr.fda.gov
Johnson
J R
JR
Tyler-Hashemi
A A
AA
Rountree
R L
RL
Sapienza
P P
PP
Ali
S F
SF
Kim
C S
CS
D000818:Animals; D002331:Carnitine / Q000494:pharmacology*; D002374:Catalase / Q000187:drug effects* / Q000378:metabolism; D004353:Drug Evaluation, Preclinical; D005230:Fatty Acids, Nonesterified / Q000378:metabolism*; D005625:Frontal Lobe / Q000187:drug effects / Q000378:metabolism; D008297:Male; D009498:Neurotoxins; D009574:Nitro Compounds; D018384:Oxidative Stress / Q000187:drug effects* / Q000502:physiology; D011422:Propionates; D051381:Rats; D017207:Rats, Sprague-Dawley; D013482:Superoxide Dismutase / Q000187:drug effects* / Q000378:metabolism
D005230:Fatty Acids, Nonesterified; D009498:Neurotoxins; D009574:Nitro Compounds; D011422:Propionates; D002374:Catalase; D013482:Superoxide Dismutase; C015392:3-nitropropionic acid; D002331:Carnitine