The control of T cell responses by dendritic cell subsets.
Dendritic cells are known as the most efficient antigen-presenting cell type to activate naïve T cells; however, they are able to do more than just efficiently present antigen to T cells. They are key modulators of the immune response that can influence Th cell differentiation by preferentially inducing Th type 1 or 2 cell responses, and the differential polarisation of CD4(+) T cells appears to be mediated by discrete dendritic cell subsets.
Reid
S D
SD
Roche Milano Ricerche, Milan, 20132, Italy.
Penna
G
G
Adorini
L
L
D000818:Animals; D017951:Antigen Presentation; D000945:Antigens, Differentiation, T-Lymphocyte; D016207:Cytokines / Q000378:metabolism; D003713:Dendritic Cells / Q000145:classification*; D006801:Humans; D051379:Mice; D013601:T-Lymphocytes / Q000276:immunology*
D000945:Antigens, Differentiation, T-Lymphocyte; D016207:Cytokines