title: [Incidental prostatic cancer].
abstract: OBJECTIVE
  To evaluate the incidence of incidental prostate cancer and PSA ability to predict its presence.
  
  
  METHODS
  Retrospective study of 862 patients undergoing prostate surgery between 1994 and 1997, both inclusive. Digital rectal examination provided no suspicion of neoformation. Mean age was 68 +/- 7.5 years. Mean PSA, 8.3 +/- 10 ng/ml (Hybritech). 15% patients had previously undergone at least one ultrasound-guided biopsy in the peripheral area. 55% patients underwent retropubic surgery and the remaining 45% prostate transurethral resection. Ultrasound prostate volume for both patient groups was 107 +/- 63 cc and 45 +/- 25 cc, respectively.
  
  
  RESULTS
  Incidental cancer was found in 6% patients; 65% were T1a and 35% T1b. Mean PSA concentration in cancer patients was almost significantly (p = 0.05) higher than in patients with BPH. Patients with PSA > 10 ng/ml presented a significantly higher incidence of cancer (p = 0.02). Patients with previous prostate biopsy showed a cancer incidence rate of 12% versus 5% patients with no previous biopsy (p = 0.001).
  
  
  CONCLUSIONS
  Incidence of incidental prostate cancer was 6%. PSA was not a good predictor of incidental cancer. Patients with PSA > 10 ng/ml, showed higher incidence of cancer. Younger patients with PSA > 10 ng/ml, and at least one negative biopsy of the peripheral area should undergo biopsy of the transitional area prior to surgery.
authors.affiliation: Servicio de Urología, H.G.U. Gregorio Marañón, Madrid.
authors.forename: F
authors.initials: F
authors.lastname: Herranz Amo
authors.forename: J M
authors.initials: JM
authors.lastname: Díez Cordero
authors.forename: F
authors.initials: F
authors.lastname: Verdú Tartajo
authors.forename: F
authors.initials: F
authors.lastname: Leal Hernández
authors.forename: A
authors.initials: A
authors.lastname: Bielsa Carrillo
authors.forename: J
authors.initials: J
authors.lastname: García Burgos
authors.forename: D
authors.initials: D
authors.lastname: Subirá Ríos
mesh_terms: D000368:Aged; D006801:Humans; D015994:Incidence; D008297:Male; D011237:Predictive Value of Tests; D017430:Prostate-Specific Antigen / Q000097:blood; D011470:Prostatic Hyperplasia / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology*; D012189:Retrospective Studies
chemical_list: D017430:Prostate-Specific Antigen