title: [A preliminary report of antiscar formation effect by subconjunctival injection of mitomycin C before trabeculectomy in glaucoma].
abstract: To improve the function of filtering blebs and increase the successful rate of the trabeculectomy, mitomycin C injection 0.02 mg.ml-1 was given subconjunctivally at the operative site before trabeculectomy in 32 patients (38 eyes) with moderate or late glaucoma. All patients were followed up for 6 to 12 months. The results showed that the rate of functional blebs were 93.7%. The successful rate of the operation was 94.7%. The common postoperative complication was shallow anterior chamber (7.9%). These findings indicate that the subconjunctival injection of mitomycin C before operation is a safe, effective method for antiscar formation.
authors.affiliation: Department of Ophthalmology, Xiangya Hospital, Hunan Medical University, Changsha.
authors.forename: X
authors.initials: X
authors.lastname: Xia
authors.forename: P
authors.initials: P
authors.lastname: Huang
authors.forename: S
authors.initials: S
authors.lastname: Liu
mesh_terms: D000328:Adult; D000368:Aged; D000477:Alkylating Agents / Q000008:administration & dosage*; D002921:Cicatrix / Q000209:etiology / Q000517:prevention & control; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000601:surgery*; D005902:Glaucoma, Open-Angle / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D014130:Trabeculectomy / Q000009:adverse effects
chemical_list: D000477:Alkylating Agents; D016685:Mitomycin