Severe tracheobronchial stenosis in a patient with Crohn's disease.
Tracheobronchial involvement in Crohn's disease is rare, usually associated with symptoms of tracheobronchitis, and typically responds well to steroids. The authors report a case of a 29-yr old patient with Crohn's disease, who presented with dyspnoea, fever, and a productive cough. Computed tomography of the chest revealed extensive nodular tracheobronchial stenosis, that was accompanied by severe mucosal inflammation at bronchoscopy. High-dose oral steroids diminished the mucosal inflammation, but had limited efficacy on the underlying tracheobronchial stenosis. It is speculated that this relative ineffectiveness of steroids may be due to the persistence of the untreated inflammatory process.
Kuźniar
T
T
Dept of Internal Medicine and Allergology, Medical University of Wroclaw, Poland.
Sleiman
C
C
Brugière
O
O
Groussard
O
O
Mal
H
H
Mellot
F
F
Pariente
R
R
Malolepszy
J
J
Fournier
M
M
D000328:Adult; D001706:Biopsy; D001980:Bronchi / Q000473:pathology; D001982:Bronchial Diseases / Q000175:diagnosis; D001999:Bronchoscopy; D003424:Crohn Disease / Q000175:diagnosis*; D006801:Humans; D008297:Male; D014057:Tomography, X-Ray Computed; D014135:Tracheal Stenosis / Q000175:diagnosis* / Q000473:pathology