title: Treatment and pain relief of ulcerative hemangiomas with a polyurethane film.
abstract: BACKGROUND
  Hemangiomas are the most common tumors occurring in young children. The most common complication in the growing phase of hemangioma is ulceration.
  
  
  OBJECTIVE
  We report healing, pain relief and evolutive effects of a polyurethane film in 8 cases with ulcerative hemangiomas.
  
  
  RESULTS
  In all 8 infants, prompt pain relief and healing within 1-2 months were observed. An increased regression was also noted within 2-4 months, when the hemangiomas were in the normal proliferative phase.
  
  
  CONCLUSIONS
  As far as the authors know, there is no explanation for the effectiveness of polyurethane film. Explanations could be the occlusive effects of the film inhibiting proliferation or the decrease in blood flow. As primary initial therapeutic approach in ulcerative hemangiomas, we advocate the application of a polyurethane film. This therapy is painless and suitable for children.
authors.affiliation: Department of Dermato-Venereology, University Hospital Rotterdam and Erasmus University Rotterdam, The Netherlands.
authors.forename: A P
authors.initials: AP
authors.lastname: Oranje
authors.forename: F B
authors.initials: FB
authors.lastname: de Waard-van der Spek
authors.forename: A C
authors.initials: AC
authors.lastname: Devillers
authors.forename: P C
authors.initials: PC
authors.lastname: de Laat
authors.forename: G C
authors.initials: GC
authors.lastname: Madern
mesh_terms: D005260:Female; D006391:Hemangioma / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D008297:Male; D009779:Occlusive Dressings; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D011140:Polyurethanes / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000150:complications / Q000188:drug therapy*; D012883:Skin Ulcer / Q000188:drug therapy* / Q000209:etiology; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects
chemical_list: D011140:Polyurethanes