title: Thrombosis associated with the prothrombin G-->A20210 mutation in Behçet's disease.
abstract: We describe 2 cases of Behcet's disease (BD) and thrombosis who were heterozygous for the prothrombin G-->A20210 mutation. In one case, progressive uncontrolled thromboses led to death. Case-control studies are needed to support the hypothesis of the role of the prothrombin A20210 allele as a risk factor for venous thrombosis in some patients with BD.
authors.affiliation: Rheumatic Disease Unit, Arcispedale S. Maria Nuova, Reggio Emilia, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Salvarani
authors.forename: K
authors.initials: K
authors.lastname: Calamia
authors.forename: M
authors.initials: M
authors.lastname: Silingardi
authors.forename: A
authors.initials: A
authors.lastname: Ghirarduzzi
authors.forename: I
authors.initials: I
authors.lastname: Olivieri
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000235:genetics*; D005260:Female; D006801:Humans; D009154:Mutation; D011516:Prothrombin / Q000235:genetics*; D013927:Thrombosis / Q000209:etiology* / Q000235:genetics*
chemical_list: D011516:Prothrombin