[Changes in hypoxic resistance and conditional avoidance reflex during hypobaric adaptation on the "flatland" and in mountains].
White rats--males with mass 200-250 g were exposed ipobaroadaptation (rise on 12,000 m with an exposition 5 minutes) with periodic testing them on gipocsition stability. After shaping in the result of gipobaroadaptation stressostability, that it was judged in 2-3 times enlarging of reserve time, rats produced conditional reflexes at active avoid (CRAA) as on plain area (760 m) so in high-mountainous (2500 m). It is observed that gipobaroadaptation increases gipocsition stability and accelerates the CRAA shaping on plain area and in mountains. The maximum effect of gipocsition stahility increasing, CRAA consolidation and perfecting of efferention synthesis at high-mountainous gipobaroadaptation rats is more significant, thah at "flat." gipobaroadaptation has important protective significance for function of a brain, decreasing its sensibility to lock of oxygen and fixing maximum adaptive responses.
Bekbolotova
A K
AK
Institute of Physiology and Experimental Pathology of High Altitude Areas of the Kirgiz Acad. Sci., Bishkek, Kirgizstan.
Zakharov
G A
GA
Zhumagulova
Zh O
ZhO
D000222:Adaptation, Physiological; D000531:Altitude; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D051381:Rats