Reversible adult respiratory distress in primary antiphospholipid syndrome.
Antiphospholipid antibody syndrome (APS) is a disorder caused by circulating antibodies reacting with biological membranes and characterized by recurrent thrombosis, chronic thrombocytopenia and miscarriages. It has been reported to occur either as a primary syndrome or secondary to systemic autoimmune disorders. We describe a case of primary APS in a young patient, in whom the clinical course was particularly severe and complicated by a respiratory distress syndrome. The patient was resistant to a number of treatments, and eventually responded to intravenous high dose corticosteroids.
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Division of Hematology OFederico IIO University, Naples, Italy.
Rocco
S
S
De Lucia
D
D
Silvia
C
C
Lucania
A
A
Servillo
G
G
Valentini
G
G
Rotoli
B
B
D000293:Adolescent; D016736:Antiphospholipid Syndrome; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D012127:Respiratory Distress Syndrome, Newborn / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology
D005938:Glucocorticoids; D008775:Methylprednisolone