title: [Geographic distribution of Mycobacterium avium-intracellulare complex serovars isolated from patients in five cities of Japan].
abstract: Mycobacterium avium-intracellulare complex (MAC), isolated from patients with MAC infection in five cities in Japan, was classified into M. avium and M. intracellulare by DNA-DNA hybridization assay (DDH). They were also classified into serovars by seroagglutination test and thin-layer chromatography (TLC) detecting serovar-specific antigens. The ratios of M. avium: intracellulare isolated in Sendai, Maebashi, Kobe, Hamamatsu, and Kumamoto, were 100:0, 26:16, 37:12, 37:39, and 17:54, respectively. It was high in the northern city, Sendai, whereas the ratio in the southern city, Kumamoto, was low. The main serovars detected in Sendai and Maebashi were 8 and 4. Various serovars including a new type of M. intracellulare were detected with main serovars 16 and 7 in Kumamoto. M. intracellulare including main serovar 16, and M. avium including main serovar 4, were detected in the same ratio in Hamamatsu. M. avium including main serovars 8 and 4, was detected in considerable high ratio in Kobe. Geographic distribution was observed in both species of MAC and serovars.
authors.affiliation: Department of Bacteriology, Kobe Institute of Health, Hyogo, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Sato
mesh_terms: D006801:Humans; D007564:Japan; D015269:Mycobacterium avium Complex / Q000302:isolation & purification*; D012703:Serotyping