title: Evidence for involvement of prostaglandin I2 as a major nociceptive mediator in acetic acid-induced writhing reaction: a study using IP-receptor disrupted mice.
authors.affiliation: Department of Pharmacology, School of Pharmaceutical Sciences, Kitasato University, Tokyo.
authors.forename: S
authors.initials: S
authors.lastname: Ohishi
authors.forename: A
authors.initials: A
authors.lastname: Ueno
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: T
authors.initials: T
authors.lastname: Murata
authors.forename: F
authors.initials: F
authors.lastname: Ushikubi
authors.forename: S
authors.initials: S
authors.lastname: Narumiya
mesh_terms: D015121:6-Ketoprostaglandin F1 alpha / Q000378:metabolism; D019342:Acetic Acid / Q000633:toxicity; D018712:Analgesics, Non-Narcotic / Q000494:pharmacology; D000818:Animals; D001202:Ascitic Fluid / Q000378:metabolism; D015232:Dinoprostone / Q000378:metabolism; D011464:Epoprostenol / Q000502:physiology*; D007213:Indomethacin / Q000494:pharmacology; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D018345:Mice, Knockout; D009619:Nociceptors / Q000187:drug effects / Q000502:physiology*; D010146:Pain / Q000139:chemically induced / Q000503:physiopathology*; D010147:Pain Measurement; D044006:Receptors, Epoprostenol; D011982:Receptors, Prostaglandin / Q000187:drug effects / Q000235:genetics / Q000502:physiology*
chemical_list: D018712:Analgesics, Non-Narcotic; D044006:Receptors, Epoprostenol; D011982:Receptors, Prostaglandin; D015121:6-Ketoprostaglandin F1 alpha; D011464:Epoprostenol; D015232:Dinoprostone; D019342:Acetic Acid; D007213:Indomethacin