title: Acute abdomen and lupus enteritis: thrombocytopenia and pneumatosis intestinalis as indicators for surgery.
abstract: Bowel symptoms occur often in systemic lupus erythematosus (SLE), but enteric complications in patients on steroid therapy are rare. We report a case of a 14-year-old Mexican girl with SLE on high-dose steroid therapy complicated by abdominal vasculitis and small bowel perforation. Accompanying this serious complication were thrombocytopenia and radiographic changes of pneumatosis intestinalis. These findings suggested necrotizing enteritis and prompted urgent surgery. Four jejunal perforations, pneumatosis intestinalis, and submucosal vasculitis were present in the resected specimen. Persistent SLE activity responded to cyclophosphamide, which is indicated in patients with digestive symptoms who fail to respond to high-dose steroids.
authors.affiliation: Division of Surgery, Instituto Nacional de la Nutrición Salvador Zubirán, Mexico City, Mexico.
authors.forename: F
authors.initials: F
authors.lastname: Alcocer-Gouyonnet
authors.forename: C
authors.initials: C
authors.lastname: Chan-Nuñez
authors.forename: J
authors.initials: J
authors.lastname: Hernández
authors.forename: J
authors.initials: J
authors.lastname: Guzmán
authors.forename: A
authors.initials: A
authors.lastname: Gamboa-Domínguez
mesh_terms: D000006:Abdomen, Acute / Q000209:etiology* / Q000601:surgery; D000293:Adolescent; D004751:Enteritis / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology / Q000601:surgery; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D011006:Pneumatosis Cystoides Intestinalis / Q000209:etiology / Q000601:surgery; D012700:Serositis / Q000209:etiology / Q000601:surgery; D013921:Thrombocytopenia / Q000209:etiology