Capillary gas chromatography/mass spectrometry with chemical ionization and negative ion detection for confirmation of identity of patulin in apple juice.
Gas chromatography/mass spectrometry (GC/MS) with negative ion chemical ionization permits detection of underivatized patulin in apple juice extracts while minimizing co-extractive responses. The technique has been used with a variety of capillary columns in quadrupole, ion trap, and magnetic sector GC/MS instruments to confirm presumptive findings of patulin in apple juice at concentrations ranging from 68 to 3700 micrograms/L. The demonstrated ability to use any of these 3 mass spectrometers and several capillary columns to confirm the identity of patulin are significant strengths of the technique.
Roach
J A
JA
U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, Washington, DC 20204, USA.
White
K D
KD
Trucksess
M W
MW
Thomas
F S
FS
D001628:Beverages / Q000032:analysis*; D005506:Food Contamination; D005638:Fruit; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D010365:Patulin / Q000032:analysis*; D012680:Sensitivity and Specificity
D010365:Patulin