title: Bone mineral and migratory patterns in uncemented total knee arthroplasties: a randomized 5-year follow-up study of 38 knees.
abstract: We measured the amount of bone mineral in the medial tibial condyle 1 week postoperatively, after 1 year and after 4-5 years in 38 arthrotic knees randomized to a Freeman-Samuelson hydroxyapatite-coated (FS HA) or a Miller-Galante II (MG II) total knee arthroplasty. Clinically excellent results were recorded in both groups after 5 years. At the last follow-up, the overall decrease in bone mineral was 26%, as measured by triple-energy X-ray absorptiometry. The decrease was larger in FS HA knees than in MG II knees after 4-5 years, indicating stress-shielding of the proximal tibia. Radiostereometry at 1 and 5 years showed smaller maximum total point motion, maximum subsidence and varus or valgus tilt in the FS HA group. There was a tendency towards a reversed relationship between subsidence and change in bone mineral after 1 year, but not after 4-5 years. Distal fixation of the stem in the Freeman-Samuelson hydroxyapatite-coated (FS HA) components might explain the more pronounced loss of bone mineral in the medial tibial condyle.
authors.affiliation: Department of Orthopaedics, Institute of Surgical Sciences, Göteborg University, Sweden.
authors.forename: L R
authors.initials: LR
authors.lastname: Regnér
authors.forename: L V
authors.initials: LV
authors.lastname: Carlsson
authors.forename: J N
authors.initials: JN
authors.lastname: Kärrholm
authors.forename: T H
authors.initials: TH
authors.lastname: Hansson
authors.forename: P G
authors.initials: PG
authors.lastname: Herberts
authors.forename: J
authors.initials: J
authors.lastname: Swanpalmer
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D015519:Bone Density; D002484:Cementation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery; D011475:Prosthesis Failure; D013977:Tibia / Q000000981:diagnostic imaging / Q000378:metabolism