title: Peliosis hepatis in a dog infected with Bartonella henselae.
abstract: A 6-year-old spayed female Golden Retriever was examined because of generalized weakness and abdominal distention. Abdominal ultrasonography revealed a large quantity of peritoneal fluid. In addition, the liver appeared larger than normal and contained multiple, small, nodular masses and cyst-like structures. Abdominal exploratory surgery was performed, and 5 L of serosanguineous peritoneal fluid was removed. Gross lesions were not found in the stomach, kidneys, intestines, adrenal glands, or urinary bladder. There were diffuse cystic nodules in all liver lobes. The dog did not recover from anesthesia. A diagnosis of peliosis hepatis was made on the basis of gross and histologic appearance of the liver. A polymerase chain reaction assay revealed Bartonella henselae DNA in liver specimens. To our knowledge, this is the first report of molecular evidence of B henselae infection in a dog with peliosis hepatis.
authors.affiliation: Department of Clinical Science, College of Veterinary Medicine, University of Illinois, Urbana 61801, USA.
authors.forename: B E
authors.initials: BE
authors.lastname: Kitchell
authors.forename: T M
authors.initials: TM
authors.lastname: Fan
authors.forename: D
authors.initials: D
authors.lastname: Kordick
authors.forename: E B
authors.initials: EB
authors.lastname: Breitschwerdt
authors.forename: G
authors.initials: G
authors.lastname: Wollenberg
authors.forename: C A
authors.initials: CA
authors.lastname: Lichtensteiger
mesh_terms: D000818:Animals; D001202:Ascitic Fluid / Q000000981:diagnostic imaging / Q000601:surgery / Q000662:veterinary; D001474:Bartonella Infections / Q000150:complications / Q000662:veterinary*; D018416:Bartonella henselae / Q000235:genetics / Q000302:isolation & purification; D001707:Biopsy, Needle / Q000662:veterinary; D004269:DNA, Bacterial / Q000032:analysis; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000601:surgery; D004285:Dogs; D004322:Drainage / Q000662:veterinary; D005260:Female; D008099:Liver / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology; D010382:Peliosis Hepatis / Q000382:microbiology / Q000601:surgery / Q000662:veterinary*; D016133:Polymerase Chain Reaction / Q000662:veterinary; D014463:Ultrasonography
chemical_list: D004269:DNA, Bacterial