title: Isolation and structural elucidation of two new glycosides from sage (Salvia officinalis L.).
abstract: Six compounds, 1-O-(2,3, 4-trihydroxy-3-methyl)butyl-6-O-feruloyl-beta-D-glucopyranoside, ethyl beta-D-glucopyranosyl tuberonate, p-hydroxybenzoic acid, (-)-hydroxyjasmonic acid, caffeic acid, and 4-hydroxyacetophenone 4-O-[5-O-(3, 5-dimethoxy-4-hydroxybenzoyl)-beta-D-apiofrunosyl]-(1-->2)-beta-D- glu copyranoside, were isolated from the n-butanol-soluble fraction of sage leaf extracts. Their structures were determined by spectral methods (MS, NMR, and 2D-NMR), and their antioxidant activities were measured. Among them, two new glycosides were elucidated. All of these compounds showed DPPH free radical scavenging activity at the concentration of 30 mM, and caffeic acid was the most active compound.
authors.affiliation: Department of Food Science, Rutgers University, 65 Dudley Road, New Brunswick, New Jersey 08901-8520, USA.
authors.forename: M
authors.initials: M
authors.lastname: Wang
authors.forename: H
authors.initials: H
authors.lastname: Kikuzaki
authors.forename: N
authors.initials: N
authors.lastname: Zhu
authors.forename: S
authors.initials: S
authors.lastname: Sang
authors.forename: N
authors.initials: N
authors.lastname: Nakatani
authors.forename: C T
authors.initials: CT
authors.lastname: Ho
mesh_terms: D005609:Free Radicals; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D019686:Lamiaceae / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry
chemical_list: D005609:Free Radicals; D006027:Glycosides