[Histopathologic and immunochemical changes in Sjögren's syndrome].
To research into the causes of sjögren's syndrome, we investigated the lacrimal gland tissues of 6 cases of sjogren's syndriome by using electronmicroscopy and immunochemical methods. The results revealed that at the early stage the lacrimal gland cells showed degeneration, irregular arrangement and many intracellular vacuoles. At the middle stage, some lymphocytes infliltrated into the gland tissues. And at the advanced stage, lymphocytes and collagenous fibers were there in substitution of gland cells.
Wu
X
X
Department of Ophthalmology, First Affiliated Hospital, Chengdu.
Huang
Y
Y
Yao
X
X
Hang
Z
Z
Cheng
N
N
Lei
S
S
He
G
G
Li
B
B
Chen
C
C
Mao
Z
Z
D000328:Adult; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000378:metabolism; D007150:Immunohistochemistry; D007765:Lacrimal Apparatus / Q000276:immunology / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000276:immunology / Q000473:pathology*
D007075:Immunoglobulin M