Modification of lipoproteins in uremia: oxidation, glycation and carbamoylation.
Lipoprotein modification occurs in uremic patients and in patients with end stage kidney disease under chronic renal replacement therapy. Forms of lipoprotein modification include lipid peroxidation, glycation, and carbamoylation. In this short review, we discuss the presence of these forms of lipoprotein modification and their association with various renal diseases. Methods to analyze lipoprotein modification are introduced, and functional consequences related to vascular and renal function are presented.
Galle
J
J
Department of Medicine, Division of Nephrology, University Hospital of Würzburg, Germany. J-C.Galle@mail.uni-wuerzburg.de
Wanner
C
C
D001161:Arteriosclerosis / Q000209:etiology; D003485:Cyanates / Q000097:blood; D006031:Glycosylation; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood; D015227:Lipid Peroxidation; D008074:Lipoproteins / Q000097:blood* / Q000737:chemistry; D008239:Lysine / Q000097:blood; D014511:Uremia / Q000097:blood* / Q000150:complications
D003485:Cyanates; D008074:Lipoproteins; D008239:Lysine