title: Circumscribed choroidal hemangioma: characteristic features with indocyanine green videoangiography.
abstract: OBJECTIVE
  To determine the characteristic features of indocyanine green videoangiography (ICG-V) of circumscribed choroidal hemangioma.
  
  
  METHODS
  Prospective, observational case series.
  
  
  METHODS
  Twenty-five eyes of 25 consecutive patients with circumscribed choroidal hemangioma.
  
  
  METHODS
  Indocyanine green videoangiography and intravenous fluorescein angiography (IVFA) were prospectively performed and reviewed. The specific features on ICG-V were compared with features of IVFA.
  
  
  METHODS
  The behavior of circumscribed choroidal hemangioma cases was observed with ICG-V and IVFA.
  
  
  RESULTS
  On ICG-V, earliest hyperfluorescence of circumscribed choroidal hemangioma was achieved at a mean of 27.6 seconds (range, 13-62 seconds), whereas maximum hyperfluorescence occurred at 222 seconds (range, 33-707 seconds). In the late frames, all eyes demonstrated a relative decrease in fluorescence, including 18 eyes (72%) that demonstrated "washout" of the dye. Other findings on ICG-V included intrinsic vessels in 19 eyes (76%), a late hyperfluorescent rim in 19 eyes (76%), and late frame hot spots in 14 eyes (56%). On IVFA, the earliest hyperfluorescence was achieved at a mean of 24 seconds (range, 10-66 seconds), whereas maximum hyperfluorescence occurred at a mean of 76.3 seconds (range, 21-720 seconds). Increasing hyperfluorescence in the late frames was found in all cases. Other findings included intrinsic vessels in 12 eyes (48%) and hot spots in the late frames in 9 eyes (36%).
  
  
  CONCLUSIONS
  Circumscribed choroidal hemangioma have specific characteristics on ICG-V that are not visualized with IVFA. We believe that ICG-V may become an important noninvasive tool for the diagnosis of choroidal hemangioma.
authors.affiliation: Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
authors.forename: J F
authors.initials: JF
authors.lastname: Arevalo
authors.forename: C L
authors.initials: CL
authors.lastname: Shields
authors.forename: J A
authors.initials: JA
authors.lastname: Shields
authors.forename: P G
authors.initials: PG
authors.lastname: Hykin
authors.forename: P
authors.initials: P
authors.lastname: De Potter
mesh_terms: D002830:Choroid Neoplasms / Q000175:diagnosis*; D005451:Fluorescein Angiography; D018324:Hemangioma, Capillary / Q000175:diagnosis*; D006801:Humans; D007208:Indocyanine Green; D011446:Prospective Studies; D014741:Video Recording
chemical_list: D007208:Indocyanine Green