The expression of DAZL1 in the ovary of the human female fetus.
OBJECTIVE
To determine whether DAZL1 is expressed in human fetal ovarian tissue.


METHODS
The presence of DAZL1 expression was determined by reverse transcriptase polymerase chain reaction (RT-PCR).


METHODS
Academic tertiary care medical center and research unit of university.


METHODS
Five female abortuses between the 19th and 22nd week of gestational age.


METHODS
Fetal ovarian tissues were collected immediately after the cessation of the heart beat.


METHODS
The product of RT-PCR.


RESULTS
DAZL1 expression was detected in all five samples.


CONCLUSIONS
DAZL1 is not only expressed in human testes but also in ovaries. It may play a role in germ cell survival and gonad development in both sexes.
Tsai
M Y
MY
Kaohsiung Chang-Gung Memorial Hospital, Kaohsiung County, Taiwan. mtsai1@ms8.hinet.net
Chang
S Y
SY
Lo
H Y
HY
Chen
I H
IH
Huang
F J
FJ
Kung
F T
FT
Lu
Y J
YJ
D000028:Abortion, Induced; D000328:Adult; D015139:Blotting, Southern; D004717:Endometrium / Q000502:physiology; D005260:Female; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000235:genetics; D010053:Ovary / Q000196:embryology* / Q000502:physiology*; D011506:Proteins / Q000235:genetics*; D016601:RNA-Binding Proteins; D020133:Reverse Transcriptase Polymerase Chain Reaction
C101358:DAZL protein, human; D011506:Proteins; D016601:RNA-Binding Proteins