title: Cellular effects of a new farnesyltransferase inhibitor, RPR-115135, in a human isogenic colon cancer cell line model system HCT-116.
authors.affiliation: Laboratory of Molecular Pharmacology, National Institutes of Health, Bethesda, Maryland 20892, USA. patrusso@hp380.ist.unige.it
authors.forename: P
authors.initials: P
authors.lastname: Russo
authors.forename: C
authors.initials: C
authors.lastname: Ottoboni
authors.forename: C
authors.initials: C
authors.lastname: Falugi
authors.forename: W
authors.initials: W
authors.lastname: Reinhold
authors.forename: J F
authors.initials: JF
authors.lastname: Riou
authors.forename: S
authors.initials: S
authors.lastname: Parodi
authors.forename: P M
authors.initials: PM
authors.lastname: O'Connor
mesh_terms: D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors*; D003110:Colonic Neoplasms / Q000473:pathology*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D051231:Farnesyltranstransferase; D006801:Humans; D008954:Models, Biological; D014407:Tumor Cells, Cultured
chemical_list: D004791:Enzyme Inhibitors; D019883:Alkyl and Aryl Transferases; D051231:Farnesyltranstransferase