Acute heart transplant rejection due to Saint John's wort.
We report here acute rejection in two transplant patients due to a metabolic interaction of St John's wort and cyclosporin.
Ruschitzka
F
F
Meier
P J
PJ
Turina
M
M
Lüscher
T F
TF
Noll
G
G
D001379:Azathioprine / Q000097:blood; D016572:Cyclosporine / Q000097:blood*; D004347:Drug Interactions; D006084:Graft Rejection / Q000139:chemically induced*; D016027:Heart Transplantation; D006801:Humans; D020902:Hypericum / Q000009:adverse effects*; D007166:Immunosuppressive Agents / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010946:Plants, Medicinal
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D001379:Azathioprine