title: Reactive vascular lesion of nasal septum simulating angiosarcoma in a cocaine abuser.
abstract: We report the case of an exuberant ulcerative angiomatoid nasal lesion in a cocaine abuser. The lesion was made up of polymorphous endothelial cells with occasional mitoses, arranged in a lobular pattern with infiltrative-looking areas. There were extensive areas of thrombosis with focal recanalization. Intravascular proliferation was not observed. The clinical, radiological, and histological features suggested hemangiosarcoma as the main differential diagnosis, but the lobular architecture of the lesion and the widespread thrombosis favoured the diagnosis of a benign reactive process.
authors.affiliation: Department of Pathology, Hospital del Mar, Autonomous University of Barcelona, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Alameda
authors.forename: J
authors.initials: J
authors.lastname: Fontane
authors.forename: J M
authors.initials: JM
authors.lastname: Corominas
authors.forename: J
authors.initials: J
authors.lastname: Lloreta
authors.forename: S
authors.initials: S
authors.lastname: Serrano
mesh_terms: D000328:Adult; D000798:Angiomatosis / Q000175:diagnosis* / Q000473:pathology; D001706:Biopsy; D019970:Cocaine-Related Disorders / Q000150:complications*; D003937:Diagnosis, Differential; D006394:Hemangiosarcoma / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009300:Nasal Septum; D009668:Nose Diseases / Q000175:diagnosis* / Q000473:pathology