Simple redox-linked proton-transfer design: new insights from structures of quinol-fumarate reductase.
The mitochondrial bioenergetics field has experienced an exciting breakthrough with the recent structure determination of several key membrane complexes. The latest addition to this line of structures, that of quinol-fumarate reductase, provides new insights into the mechanism of energy transduction.
Ohnishi
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Department of Biochemistry and Biophysics, Johnson Research Foundation, University of Pennsylvania, Philadelphia, PA 19104, USA. ohnishi@mail.med.upenn.edu.
Moser
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Dutton
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Yano
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D018360:Crystallography, X-Ray; D004734:Energy Metabolism; D010084:Oxidation-Reduction; D011487:Protein Conformation; D011522:Protons; D011809:Quinones / Q000378:metabolism*; D013385:Succinate Dehydrogenase / Q000737:chemistry*
D011522:Protons; D011809:Quinones; D013385:Succinate Dehydrogenase