title: Determination of metallic ion transfer from an implanted prosthesis by the PIXE method.
abstract: Prostheses can release some metallic elements to the surrounding tissues, particularly when they are not covered with a biomaterial layer and when an unsealing process happens. We try to measure major and trace elements in these tissues with an experimentally sensitive method. Proton-induced X-ray emission is used to detect about 10 elements in tissue. Tissues are calcinated and deposited in a thin layer before irradiation. Results are obtained in a standard and samples from three patients. We observe contamination by Ti, Cr, Ni, and Zn in the tissues. Correlations are to be studied between these atomic transfers and prosthesis in the patient.
authors.affiliation: Laboratoire de Physique Corpusculaire de Clermont-Ferrand, Université Blaise Pascal, Aubière, France.
authors.forename: H
authors.initials: H
authors.lastname: Oudadesse
authors.forename: J L
authors.initials: JL
authors.lastname: Irigaray
authors.forename: V
authors.initials: V
authors.lastname: Brun
authors.forename: S
authors.initials: S
authors.lastname: Terver
authors.forename: G
authors.initials: G
authors.lastname: Vanneuville
mesh_terms: D006622:Hip Prosthesis; D007720:Knee Prosthesis; D008670:Metals / Q000032:analysis*; D013052:Spectrometry, X-Ray Emission
chemical_list: D008670:Metals