title: [Changes in the lipid profile and thyroid function in adult patients with hypopituitarism after substitutive treatment with growth hormone].
abstract: BACKGROUND
  Adult growth hormone (GH) deficiency is associated with changes in serum lipid levels that can modify after GH substitution.
  
  
  METHODS
  We studied 18 patients with GH deficiency treated with GH for 18 or 24 months.
  
  
  RESULTS
  A decrease of total cholesterol, LDL with an increase in HDL without triglycerides changes was observed. T4 levels decreased and T3 increased.
  
  
  CONCLUSIONS
  The GH substitution treatment in patients with GH deficiency improves the lipid profile and promotes the T4 to T3 conversion.
authors.affiliation: Servicio de Endocrinología, Ciutat Sanitària i Universitària de Bellvitge, L'Hospitalet de Llobregat, Barcelona. iroigsag@jet.es
authors.forename: J M
authors.initials: JM
authors.lastname: Gómez Sáez
authors.forename: N
authors.initials: N
authors.lastname: Gómez Arnaiz
authors.forename: J
authors.initials: J
authors.lastname: Soler Ramón
mesh_terms: D000328:Adult; D004311:Double-Blind Method; D005260:Female; D019382:Human Growth Hormone / Q000008:administration & dosage* / Q000172:deficiency; D006801:Humans; D007018:Hypopituitarism / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D018709:Statistics, Nonparametric; D013961:Thyroid Gland / Q000187:drug effects / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D008055:Lipids; D019382:Human Growth Hormone