title: Surgical site infections at the National Cancer Institute in Mexico: a case-control study.
abstract: OBJECTIVE
  To quantify the surgical infection rate and to identify risk factors associated with surgical site infection.
  
  
  METHODS
  We conducted a case-control study of all surgical patients between January 1, 1993, and June 30, 1994. The frequency of surgical site infection per 100 surgeries was calculated. The odds ratio (OR) was estimated by using logistic regression analysis.
  
  
  METHODS
  A 130-bed tertiary-care teaching hospital for adult patients with cancer.
  
  
  RESULTS
  The study followed 3372 surgeries. Three hundred thirteen patients had a surgical site infection (rate per 100 surgeries: 9. 30). The risk factors associated with surgical site infection were diabetes mellitus (OR = 2.5, 95% confidence interval [CI] = 1.27-4. 91), obesity (OR = 1.76, 95% CI = 1.14-2.7), presence of surgical drains for >5 and <16 days (OR = 1.84, 95% CI = 1.02-3.31), and presence of surgical drains for >/=16 days (OR = 2.14, 95% CI = 1. 0-4.6). The bacteria most frequently isolated were Escherichia coli 38 (21.8% of the total of microorganisms found), Pseudomonas sp 22 (12.6%), Staphylococcus aureus 16 (9.2%), and coagulase-negative Staphylococcus 25 (13.6%). The coexistence of other nosocomial infections was greater among the cases (OR = 1.8, 95% CI = 1.1-3.1) than in the control group.
  
  
  CONCLUSIONS
  The surgical site infection rate in our hospital is slightly higher than the rates reported for general hospitals. The risk factors associated with surgical site infection are similar to those previously reported. Diabetes mellitus, obesity, and prolonged presence of a surgical drain increased the risk of infection.
authors.affiliation: Department of Infectious Diseases and the Clinical Research Investigation Division, Instituto Nacional de Cancerología, Mexico, D.F 14000, Mexico.
authors.forename: D
authors.initials: D
authors.lastname: Vilar-Compte
authors.forename: A
authors.initials: A
authors.lastname: Mohar
authors.forename: S
authors.initials: S
authors.lastname: Sandoval
authors.forename: M
authors.initials: M
authors.lastname: de la Rosa
authors.forename: P
authors.initials: P
authors.lastname: Gordillo
authors.forename: P
authors.initials: P
authors.lastname: Volkow
mesh_terms: D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000145:classification / Q000209:etiology*; D002173:Cancer Care Facilities / Q000706:statistics & numerical data*; D016022:Case-Control Studies; D003428:Cross Infection / Q000145:classification / Q000209:etiology*; D048909:Diabetes Complications; D004322:Drainage / Q000009:adverse effects; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D017053:Infection Control / Q000379:methods*; D016015:Logistic Models; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications / Q000601:surgery*; D009765:Obesity / Q000150:complications; D016017:Odds Ratio; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000145:classification / Q000453:epidemiology* / Q000209:etiology*