Human contact with cattle, dogs and monkeys and genetic diversity of measles viruses.
There is a very close contact among humans, cattle, dogs and monkeys in developing countries. That could lead to genetic alteration in morbillivirus isolates of measles, rinderpest, canine distemper. Emergence of novel morbillivirus strains and failures of prophylactic viral vaccines should be monitored by characterisation of genetic profiles of isolates in different species. Incorporation of additional epitopes in existing prophylactic vaccines should minimise vaccine failures attributable to such novel strains.
Arya
S C
SC
Centre for Logistical Research and Innovation, Greater Kailash-II, New Delhi, India.
D000818:Animals; D002417:Cattle; D002460:Cell Line; D004285:Dogs; D014644:Genetic Variation; D006801:Humans; D008253:Macaca mulatta; D008457:Measles / Q000235:genetics / Q000662:veterinary*; D008459:Measles virus / Q000235:genetics*