Longitudinal study of neurotoxicity with occupational exposure to aluminum dust.
Two cross-sectional studies were conducted at a German aluminum (Al) powder plant to evaluate possible nervous system effects from occupational Al exposure. The investigation included biological monitoring, a neuropsychological test battery, and event-related P300 potentials. Neurophysiologic findings in workers chronically exposed to Al dust did not differ from non-Al-exposed controls from the same plant. The authors suggest that chronic exposure to Al dust, at the levels documented in this study, does not induce measurable cognitive decline.
Letzel
S
S
Institute and Outpatient Department for Occupational, Social and Environmental Medicine, University of Erlangen-Nuremberg, Erlangen, Germany. stephan.letzel@rzmail.uni-erlangen.de
Lang
C J
CJ
Schaller
K H
KH
Angerer
J
J
Fuchs
S
S
Neundörfer
B
B
Lehnert
G
G
D000328:Adult; D000368:Aged; D000535:Aluminum / Q000009:adverse effects*; D004391:Dust / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology*; D016273:Occupational Exposure
D004391:Dust; D000535:Aluminum