title: A novel and very peculiar HincII polymorphism in the 5' region of the human neurofibromatosis type 1 (NF1) gene.
abstract: We report a HincII polymorphism in the 5' end of the neurofibromatosis type 1 gene (NF1) as detected with a probe made of exons 1 to 4a (nucleotides 2 to 401 of the cDNA). This HincII site is most probably in an intron. Evidence presented suggests the probe reveals not one but two similar polymorphisms.
authors.affiliation: Département de Microbiologie, Faculté de Médecine, Université de Sherbrooke, Québec, Canada.
authors.forename: L J
authors.initials: LJ
authors.lastname: Fang
authors.forename: J
authors.initials: J
authors.lastname: Feingold
authors.forename: B
authors.initials: B
authors.lastname: Lemieux
authors.forename: J P
authors.initials: JP
authors.lastname: Thirion
mesh_terms: D015139:Blotting, Southern; D015252:Deoxyribonucleases, Type II Site-Specific; D005091:Exons; D016514:Genes, Neurofibromatosis 1; D006801:Humans; D007438:Introns; D009456:Neurofibromatosis 1 / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D012016:Reference Values
chemical_list: D015252:Deoxyribonucleases, Type II Site-Specific; C024400:GTYRAC-specific type II deoxyribonucleases