title: [Children with stumbling gait due to acute spinal cord compression].
abstract: Three previously healthy children, two girls aged 2 and almost 5 years and a boy aged 20 months, developed a progressively stumbling gait within days. In two this occurred after a period of weeks during which they complained of, or seemed to have back pain. In all three cases acute spinal cord compression by a malignant tumour was diagnosed. Histological examination revealed Ewing sarcoma, granulocytic sarcoma and T-cell lymphoma. Surgical decompression led to complete neurological recovery. Although rare, acute spinal cord compression during childhood is a medical emergency because of the risk of neurological morbidity. Back pain, weakness and a stumbling gait usually are the first symptoms. Sensory symptoms and sphincter dysfunction may develop later. Early recognition is essential, as prognosis depends on neurological findings and duration of symptoms when treatment is started.
authors.affiliation: Academisch Ziekenhuis Vrije Universiteit, Amsterdam.
authors.forename: M J
authors.initials: MJ
authors.lastname: Koppe
authors.forename: T G
authors.initials: TG
authors.lastname: de Haas
authors.forename: W J
authors.initials: WJ
authors.lastname: van Ouwerkerk
authors.forename: L M
authors.initials: LM
authors.lastname: Smit
authors.forename: C M
authors.initials: CM
authors.lastname: Zwaan
mesh_terms: D000208:Acute Disease; D001416:Back Pain / Q000209:etiology; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D020235:Gait Apraxia / Q000209:etiology*; D006801:Humans; D007223:Infant; D007951:Leukemia, Myeloid / Q000150:complications / Q000175:diagnosis; D016399:Lymphoma, T-Cell / Q000150:complications / Q000175:diagnosis; D008232:Lymphoproliferative Disorders / Q000150:complications / Q000175:diagnosis; D008297:Male; D012512:Sarcoma, Ewing / Q000150:complications / Q000175:diagnosis; D013117:Spinal Cord Compression / Q000150:complications* / Q000209:etiology / Q000628:therapy; D013125:Spinal Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy