Induction of COX expression by a tobacco carcinogen: implication in lung cancer chemoprevention.
Rioux
N
N
Laboratory of Etiology and Cancer Chemoprevention, Faculty of Pharmacy, Laval University, Ste-Foy, Quebec, Canada. aaa771@agora.ulaval.ca
Castonguay
A
A
D000818:Animals; D016588:Anticarcinogenic Agents / Q000494:pharmacology*; D001711:Biotransformation; D002273:Carcinogens / Q000633:toxicity*; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology*; D004790:Enzyme Induction / Q000187:drug effects; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000096:biosynthesis*; D008175:Lung Neoplasms / Q000139:chemically induced / Q000517:prevention & control*; D008565:Membrane Proteins; D051379:Mice; D009602:Nitrosamines / Q000493:pharmacokinetics / Q000633:toxicity*; D011451:Prostaglandin-Endoperoxide Synthases / Q000096:biosynthesis*; D014407:Tumor Cells, Cultured
D016588:Anticarcinogenic Agents; D002273:Carcinogens; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D008565:Membrane Proteins; D009602:Nitrosamines; C016583:4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases