Novel polycyclic guanidine alkaloids from two marine sponges of the genus Monanchora.
Two marine sponges of the genus Monanchora (Poecilosclerida, Crambeidae) have been found to contain new polycyclic guanidine alkaloids bearing the (5,6,8b)-triazaperhydroacenaphthylene skeleton. Their structures have been determined by detailed spectroscopic analysis. Dehydrobatzelladine C (1) has been isolated from M. arbuscula and crambescidins 359 (2) and 431 (3) from M. unguiculata. The chemotaxonomic implications of these findings are discussed.
Braekman
J C
JC
Laboratory of Bio-organic Chemistry, Department of Organic Chemistry, Faculty of Sciences, CP160/07, University of Brussels, 50 Avenue F. Roosevelt, 1050 Brussels, Belgium. braekman@ulb.ac.be
Daloze
D
D
Tavares
R
R
Hajdu
E
E
Van Soest
R W
RW
D000470:Alkaloids / Q000737:chemistry*; D000818:Animals; D006146:Guanidines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D011161:Porifera / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet
D000470:Alkaloids; D006146:Guanidines