title: Potassium iodide and the wolff-chaikoff effect: relevance for the dermatologist.
abstract: The inhibition of organic binding of iodide in the thyroid gland by excess iodide, resulting in the cessation of thyroid hormone synthesis, is known as the Wolff-Chaikoff effect. This review explores the nature of the Wolff-Chaikoff effect, both in terms of its potential mechanisms and its relevance to dermatologists who use potassium iodide as a therapeutic agent.
authors.affiliation: Division of Dermatology, UMDNJ-Robert Wood Johnson School of Medicine, Marlton, NJ 08053
authors.forename: W R
authors.initials: WR
authors.lastname: Heymann
mesh_terms: D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced*; D011193:Potassium Iodide / Q000009:adverse effects*; D012871:Skin Diseases / Q000188:drug therapy*
chemical_list: D000893:Anti-Inflammatory Agents; D011193:Potassium Iodide