title: The impact of foot complications on health-related quality of life in patients with diabetes.
abstract: BACKGROUND
  The concept of health-related quality of life (HRQoL) has been the focus of much debate in recent years. However, within diabetes the focus has centred on the behavioural adaptation to a chronic disease state. The impact of foot complications is witnessed regularly in the clinical setting; amputation in this group is usually preceded by ulceration and a worsening cycle of foot problems.
  
  
  OBJECTIVE
  This review sets out to investigate the literature on foot complications in those with diabetes, to assess the cost to the individual in terms of impact on everyday living.
  
  
  CONCLUSIONS
  The literature on the specific impact of foot complications is limited, but indicates a situation in which those with diabetic foot ulceration may have an even poorer HRQoL than those who have experienced an amputation related to diabetes. In order to assess the full impact of new treatments or therapeutic interventions, it is vital that further research is conducted in this area.
authors.affiliation: Wound Healing Research Unit, University of Wales College of Medicine, Cardiff, Wales, UK.
authors.forename: P
authors.initials: P
authors.lastname: Price
authors.forename: K
authors.initials: K
authors.lastname: Harding
mesh_terms: D000671:Amputation, Surgical; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000523:psychology; D017719:Diabetic Foot / Q000523:psychology; D006801:Humans; D011788:Quality of Life