Heparin-induced hyperkalemia confirmed by drug rechallenge.
Subcutaneous heparin is commonly used as a prophylaxis against deep venous thrombosis in a wide variety of hospitalized patients. As with most medications, heparin has a significant side effect profile; heparin-induced hyperkalemia is an unusual but well described side effect. To increase awareness of heparin-induced hyperkalemia and of those patients at greatest risk, we present two cases of documented hyperkalemia induced by heparin and reconfirmed by drug rechallenge.
Orlando
M P
MP
Department of Internal Medicine, University of Cincinnatti College of Medicine, Ohio, USA.
Dillon
M E
ME
O'Dell
M W
MW
D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D005260:Female; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D006947:Hyperkalemia / Q000139:chemically induced* / Q000503:physiopathology; D008297:Male
D000925:Anticoagulants; D006493:Heparin