Axon regeneration: Vaccinating against spinal cord injury.
Myelin is a potent inhibitor of axon regeneration, but has been viewed as just one of many factors that prevent regeneration after injury. So it comes as a surprise that immunization against myelin has been found to allow extensive axon regeneration after injury, without apparent autoimmune-induced demyelination.
Filbin
M T
MT
Department of Biology, Hunter College of the City University of New York, New York 10021, USA. filbin@genectr.hunter.cuny.edu
D000818:Animals; D001369:Axons / Q000502:physiology*; D007114:Immunization; D051379:Mice; D009186:Myelin Sheath / Q000276:immunology* / Q000502:physiology; D009416:Nerve Regeneration; D013119:Spinal Cord Injuries / Q000628:therapy*