title: Preliminary clinical results of window partial laryngectomy: a combined endoscopic and open technique.
abstract: Endoscopic laser resection for anterior commissure glottic carcinoma is difficult, because of inadequate exposure and close proximity to the underlying cartilage. A technique combining endoscopic carbon dioxide laser incision and an external approach creating a window in the thyroid cartilage was initially tested in a canine study and then performed in 5 patients. All patients were men, with T1 or T2 glottic or supraglottic cancer involving the anterior commissure, and had failed radiation treatment. The true or false vocal fold tumors were excised along with the paraglottic space and adjacent cartilage, with preservation of the remaining thyroid framework. The reconstruction was accomplished with placement of a sternohyoid muscle flap, by use of either a bipedicled muscle flap with overlying skin or a unipedicled muscle flap with a graft of free mucosa. The graft was secured in place with fibrin glue and laser soldering. Follow-up ranged from 11 months to 4 years and included biopsies. All patients had voice recordings before and after surgery. A tracheostomy was avoided in all patients. The hospital stays were 4 to 13 days. The voice quality was good after surgery. One patient died of unrelated causes 18 months after his surgery without evidence of recurrence. The other patients are still alive with no evidence of disease. The only complication was subcutaneous neck emphysema in 1 patient that spontaneously resolved. The results showed a satisfactory anatomic reconstruction and acceptable functions. We believe that this new combined technique is oncologically sound, may overcome the limited access seen with the endoscopic technique and the excessive cartilage resection seen with external partial laryngectomy, avoids a tracheostomy, and shortens hospital stays.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, New England Medical Center and Tufts University School of Medicine, Boston, Massachusetts 02111, USA.
authors.forename: E E
authors.initials: EE
authors.lastname: Rebeiz
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
authors.forename: D J
authors.initials: DJ
authors.lastname: Annino
authors.forename: J A
authors.initials: JA
authors.lastname: McGilligan
authors.forename: S M
authors.initials: SM
authors.lastname: Shapshay
mesh_terms: D000368:Aged; D004724:Endoscopy / Q000379:methods*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D053685:Laser Therapy; D008297:Male; D013524:Surgical Flaps; D013957:Thyroid Cartilage / Q000601:surgery; D016896:Treatment Outcome; D014827:Vocal Cords / Q000601:surgery