Hemodynamic and electrocardiographic effects of graded doses of amiodarone in healthy dogs anesthetized with morphine/alpha chloralose.
This research was designed to study acute hemodynamic and electrocardiographic effects of amiodarone and to determine an IV dose of amiodarone that minimally affects left ventricular function and does not increase the tendency for ventricular arrhythmia.
Bicer
S
S
Department of Veterinary Biosciences, College of Veterinary Medicine, Ohio State University, Columbus 43210-1092, USA.
Schwartz
D S
DS
Nakayama
T
T
Hamlin
R L
RL
D000638:Amiodarone / Q000494:pharmacology*; D000701:Analgesics, Opioid / Q000008:administration & dosage; D000768:Anesthesia, General / Q000662:veterinary*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D000818:Animals; D002698:Chloralose / Q000008:administration & dosage; D004285:Dogs / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D004562:Electrocardiography; D005260:Female; D006439:Hemodynamics; D007262:Infusions, Intravenous; D008297:Male; D009020:Morphine / Q000008:administration & dosage; D014665:Vasodilator Agents / Q000494:pharmacology*; D016277:Ventricular Function, Left
D000701:Analgesics, Opioid; D018686:Anesthetics, Intravenous; D014665:Vasodilator Agents; D002698:Chloralose; D009020:Morphine; D000638:Amiodarone