title: [Pharmacological effects of zisu and baisu].
abstract: The extract and volatile oil of zisu (Perilla frutescens) has shown significant antipyretic effect in rabbits and antiemetic effect in pigeons. The fatty oil extracted from its seeds has significant antitussive effect in mice and anti-asthmatic effect in guinea pigs. The extract, volatile oil and fatty oil of Baisu, which is of the same genus as Zisu have the same effects as those of Zisu. The acute toxicities of the extract and fatty oil of Zisu and Baisu, whether by peroral or by intraperitoneal, are similar to each other. These results indicate that Baisu has the same pharmacological effects as Zisu, and thus can be used as a substitute for Zisu.
authors.affiliation: Ningxia Institute for Drug Control, Yinchuan.
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.forename: S
authors.initials: S
authors.lastname: Tao
authors.forename: Y
authors.initials: Y
authors.lastname: Xing
authors.forename: Z
authors.initials: Z
authors.lastname: Zhu
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000494:pharmacology*; D000818:Animals; D018927:Anti-Asthmatic Agents / Q000494:pharmacology*; D000932:Antiemetics / Q000494:pharmacology*; D000996:Antitussive Agents / Q000494:pharmacology*; D001249:Asthma / Q000188:drug therapy; D003371:Cough / Q000188:drug therapy; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D005334:Fever / Q000188:drug therapy; D006168:Guinea Pigs; D019686:Lamiaceae / Q000737:chemistry; D008297:Male; D051379:Mice; D009822:Oils, Volatile / Q000302:isolation & purification / Q000494:pharmacology; D011817:Rabbits; D013045:Species Specificity; D014839:Vomiting / Q000188:drug therapy
chemical_list: D018712:Analgesics, Non-Narcotic; D018927:Anti-Asthmatic Agents; D000932:Antiemetics; D000996:Antitussive Agents; D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile