title: Renin-producing hepatoblastoma.
abstract: Renin-producing tumors of extrarenal origin are rare in children. An 8-year-old boy with hepatoblastoma and hypertension associated with a high plasma renin level is reported. After chemotherapy, the plasma renin level normalized and the hypertension spontaneously resolved. The patient underwent surgery, and a right trisegmentectomy of the liver and a partial resection of the second and third segments were performed. The tumor was as shown the source of renin by immunohistochemical study and reverse transcriptase-polymerase chain reaction.
authors.affiliation: The Department of Pediatrics, National Kyushu Cancer Center, Fukuoka, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Moritake
authors.forename: A
authors.initials: A
authors.lastname: Taketomi
authors.forename: S
authors.initials: S
authors.lastname: Kamimura
authors.forename: Y
authors.initials: Y
authors.lastname: Ikuno
authors.forename: Y
authors.initials: Y
authors.lastname: Seo
authors.forename: T
authors.initials: T
authors.lastname: Fukuda
authors.forename: H
authors.initials: H
authors.lastname: Iguchi
authors.forename: J
authors.initials: J
authors.lastname: Okamura
mesh_terms: D002648:Child; D018197:Hepatoblastoma / Q000097:blood / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000097:blood; D008113:Liver Neoplasms / Q000097:blood / Q000378:metabolism*; D008297:Male; D012083:Renin / Q000096:biosynthesis* / Q000097:blood
chemical_list: D012083:Renin