[Significance of microvessel quantity in metastasis of invasive breast carcinoma].
Microvessel quantity(MVQ), expression of CD44V6 and EGFR were studied in 48 patients with invasive breast carcinoma by CD31 immunohistochemistry. Significant differences of MVQ, CD44V6 and EGFR were observed (P < 0.01) between the groups with and without metastasis. The results suggest that angiogeneses and activation of tumor metastasis associated gene play an important role in tumor metastasis.
Wei
Q
Q
Department of Pathology, Second Affiliated Hospital, Hunan Medical University, Changsha.
Zhang
L
L
Zhou
J
J
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000098:blood supply* / Q000378:metabolism; D002196:Capillaries / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000098:blood supply* / Q000378:metabolism / Q000556:secondary; D066246:ErbB Receptors / Q000096:biosynthesis; D005260:Female; D006801:Humans; D018960:Hyaluronan Receptors / Q000096:biosynthesis; D008207:Lymphatic Metastasis; D008875:Middle Aged
D018960:Hyaluronan Receptors; D066246:ErbB Receptors