title: Treatment of facial skin using combinations of CO2, Q-switched alexandrite, flashlamp-pumped pulsed dye, and Er:YAG lasers in the same treatment session.
abstract: BACKGROUND
  Many patients who seek facial CO2 laser resurfacing for improvement of photodamage are also concerned with "dark circles" under their eyes (periorbital hyperpigmentation) and/or telangiectasia as well as various types of deep scars on their faces. CO2 laser resurfacing alone provides limited improvement for these problems.
  
  
  OBJECTIVE
  The purpose of this study was to demonstrate the conjunctive therapeutic effects of the CO2, Q-switched alexandrite, Er:YAG, and/or flashlamp-pumped pulsed dye lasers on facial skin treatments.
  
  
  METHODS
  Thirty patients who underwent CO2 laser resurfacing were treated with additional lasers specific for their cosmetic concerns. Twenty patients with facial telangiectasias were treated with the pulsed dye laser immediately prior to CO2 laser resurfacing. Eleven patients with periorbital hyperpigmentation were treated with the Q-switched alexandrite laser immediately following use of the pulsed CO2 laser. Eight patients having sharply defined acne scars were treated with the Er:YAG laser following use of the CO2 laser. All patients had peripheral feathering performed with the Er:YAG laser. Nine patients were treated with all four lasers.
  
  
  RESULTS
  In addition to significant improvement of the wrinkle scores from the CO2 laser resurfacing, patients had 75-100% clearing of the periorbital hyperpigmentation. All patients with facial telangiectasia showed virtually 100% improvement. All deep wrinkles and sharply defined scars responded with combined CO2/Er:YAG laser better than with CO2 laser resurfacing alone. All feathering was more uniform, with a more subtle transition to nontreated skin. There were no complications that could be attributed to the simultaneous use of multiple lasers.
  
  
  CONCLUSIONS
  For patients who present with multiple cosmetic complaints, combined treatment using appropriate lasers offers excellent therapeutic outcome.
authors.affiliation: Dermatology Associates and Cosmetic Laser Associates of San Diego County, Inc., La Jolla, California 92037, USA.
authors.forename: W
authors.initials: W
authors.lastname: Manuskiatti
authors.forename: R E
authors.initials: RE
authors.lastname: Fitzpatrick
authors.forename: M P
authors.initials: MP
authors.lastname: Goldman
mesh_terms: D000152:Acne Vulgaris / Q000601:surgery; D002921:Cicatrix / Q000601:surgery; D003131:Combined Modality Therapy; D062109:Dermatologic Surgical Procedures; D005145:Face / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation / Q000379:methods*; D015595:Skin Aging; D013684:Telangiectasis / Q000601:surgery; D016896:Treatment Outcome