title: Terazosine and tamsulosin in non bacterial prostatitis: a randomized placebo-controlled study.
abstract: Eighteen patients with inflammatory process of the prostate met criteria for the inclusion in the study: 1) non bacterial prostatitis; 2) no previous treatment. Then they were randomized into three groups as it follows: terazosine, tamsulosin and placebo. Alpha-blockers and placebo were given for two months, after which further uroflowmetry was performed. Symptom score was evaluated before and after treatment. Terazosine was effective in reducing TO (p = 0.01) as tamsulosin and placebo did not. Both terazosine (p = 0.034) and tamsulosin (p = 0.006) reduced max TQ as placebo did not. Symptom score significantly improved in patients receiving terazosine (p = 0.0002) and tamsulosin (p = 0.001) while insignificantly in whose receiving placebo.
authors.affiliation: Department of Urology, Catholic University of S. Cuore, Rome, Italy. s.lacquaniti@usa.net
authors.forename: S
authors.initials: S
authors.lastname: Lacquaniti
authors.forename: A
authors.initials: A
authors.lastname: Destito
authors.forename: C
authors.initials: C
authors.lastname: Servello
authors.forename: M O
authors.initials: MO
authors.lastname: Candidi
authors.forename: J M
authors.initials: JM
authors.lastname: Weir
authors.forename: G
authors.initials: G
authors.lastname: Brisinda
authors.forename: E
authors.initials: E
authors.lastname: Alcini
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D000328:Adult; D006801:Humans; D008297:Male; D011224:Prazosin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011446:Prospective Studies; D011472:Prostatitis / Q000188:drug therapy*; D013449:Sulfonamides / Q000627:therapeutic use*; D000077409:Tamsulosin
chemical_list: D000317:Adrenergic alpha-Antagonists; D013449:Sulfonamides; C041226:Terazosin; D000077409:Tamsulosin; D011224:Prazosin