title: Site specific delivery of antimicrobial agents for periodontal disease.
abstract: Controlled release delivery systems have become available for the sustained delivery of antimicrobial agents directly to the periodontal pocket. These systems have shown clinical efficacy in periodontal therapy both as adjunctive treatments and as stand-alone therapies. A review of the current state-of-the-art of site specific delivery of antimicrobial agents for the treatment of periodontal disease is provided.
authors.affiliation: Center for Dental Studies, State University of New York at Buffalo, School of Dental Medicine 14214-3008, USA.
authors.forename: S G
authors.initials: SG
authors.lastname: Ciancio
mesh_terms: D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000008:administration & dosage; D003692:Delayed-Action Preparations / Q000627:therapeutic use*; D004318:Doxycycline / Q000008:administration & dosage; D017277:Drug Approval; D006801:Humans; D008795:Metronidazole / Q000008:administration & dosage; D008911:Minocycline / Q000008:administration & dosage; D010510:Periodontal Diseases / Q000188:drug therapy*; D013752:Tetracycline / Q000008:administration & dosage; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D003692:Delayed-Action Preparations; D008795:Metronidazole; D013752:Tetracycline; D008911:Minocycline; D004318:Doxycycline; D002710:Chlorhexidine