title: Creutzfeldt-Jakob disease in a recipient of a dura mater graft processed in the US: cause or coincidence?
abstract: Iatrogenic Creutzfeldt-Jakob disease (CJD) has never been reported among recipients of dura mater grafts processed in the US. We recently investigated a report of such a case in a 72-year-old man with a typical clinical presentation of CJD. We found no evidence of CJD in either the 34-year-old donor or in other, proximal patients undergoing craniotomies. Although the graft may have caused the illness, sporadic CJD is a more likely explanation, with the graft being coincidental.
authors.affiliation: Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
authors.forename: J G
authors.initials: JG
authors.lastname: Dobbins
authors.forename: E D
authors.initials: ED
authors.lastname: Belay
authors.forename: J
authors.initials: J
authors.lastname: Malecki
authors.forename: B E
authors.initials: BE
authors.lastname: Buck
authors.forename: M
authors.initials: M
authors.lastname: Bell
authors.forename: J
authors.initials: J
authors.lastname: Cobb
authors.forename: L B
authors.initials: LB
authors.lastname: Schonberger
mesh_terms: D000328:Adult; D000368:Aged; D007562:Creutzfeldt-Jakob Syndrome / Q000453:epidemiology / Q000635:transmission*; D004388:Dura Mater / Q000637:transplantation*; D006801:Humans; D007049:Iatrogenic Disease; D008297:Male; D014481:United States / Q000453:epidemiology