title: Analysis of apatite layers on glass-ceramic particulate using FTIR and FT-Raman spectroscopy.
abstract: A nucleation and crystallization schedule was adapted to produce 40% crystalline Bioglass ceramic particulates. These particles were placed in a dynamic environment in a simulated physiologic solution (SBF-9) for time periods ranging from 10 min to 7 days. Fourier transform Raman spectroscopy (FT-Raman) and infrared spectroscopy (FTIR) were used to analyze the apatite layer formation on the particulates. FTIR determined that amorphous apatite formation took place within 2 h, with the appearance of crystalline apatite in 14 h. The vibrational frequencies obtained through FT-Raman were equivalent to those obtained using FTIR. These analyses showed that a fully crystallized apatite layer was present on the particulate after 3 days of exposure in SBF solution. These findings are consistent with those associated with amorphous Bioglass particles.
authors.affiliation: Interdisciplinary Research Centre in Biomedical Materials, Queen Mary & Westfield College, University of London, Mile End Road, London E1 4NS, United Kingdom. I.U.Rehman@qmw.ac.uk
authors.forename: I
authors.initials: I
authors.lastname: Rehman
authors.forename: M
authors.initials: M
authors.lastname: Karsh
authors.forename: L L
authors.initials: LL
authors.lastname: Hench
authors.forename: W
authors.initials: W
authors.lastname: Bonfield
mesh_terms: D001031:Apatites / Q000737:chemistry*; D001672:Biocompatible Materials / Q000737:chemistry*; D002516:Ceramics / Q000737:chemistry*; D005898:Glass / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman
chemical_list: D001031:Apatites; D001672:Biocompatible Materials