[Arthrotec treatment of rheumatoid arthritis].
OBJECTIVE
To try arthrotek, a combined drug, in patients with rheumatoid arthritis (RA).


METHODS
10 RA women aged 30 to 60 years with endoscopically verified minimal affection of gastroduodenal mucosa (not more than 25 hemorrhages and/or 5 erosions) received arthrotek (1 tablet 3 times a day for 3 months). The efficacy was judged by changes in the joints and gastroduodenal lesions.


RESULTS
The 3-month treatment produced positive changes in the main auricular and gastroduodenal symptoms. Side effects (head ache, diarrhea, sleepiness) disappeared after reducing the day dose to 2 tablets.


CONCLUSIONS
Arthrotek proved highly effective against RA. It is also a good gastroprotector promoting healing of gastroduodenal erosions.
Iakushin
S S
SS
Filonenko
S P
SP
Dediunina
R S
RS
Lukina
I M
IM
D000284:Administration, Oral; D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004008:Diclofenac / Q000008:administration & dosage / Q000627:therapeutic use*; D004338:Drug Combinations; D016145:Endoscopy, Digestive System; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D016595:Misoprostol / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; C078133:Arthrotec; D004338:Drug Combinations; D016595:Misoprostol; D004008:Diclofenac