Chemical process evolution of efavirenz, a potent non-nucleosidal HIV reverse transcriptase inhibitor.
Chen
C Y
CY
Department of Process Research, Merck Research Laboratories, Rahway, NJ 07065, USA. cheng_chen@merck.com
Tan
L
L
D000480:Alkynes; D048588:Benzoxazines; D003521:Cyclopropanes; D006678:HIV / Q000201:enzymology; D008958:Models, Molecular; D015394:Molecular Structure; D010078:Oxazines / Q000138:chemical synthesis* / Q000737:chemistry*; D018894:Reverse Transcriptase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
D000480:Alkynes; D048588:Benzoxazines; D003521:Cyclopropanes; D010078:Oxazines; D018894:Reverse Transcriptase Inhibitors; C098320:efavirenz