title: [Effect of ischemia/reperfusion in cardiac surgery with cardiopulmonary bypass on nitric oxide levels of peripheral blood in patients].
abstract: To examine the effect of ischemia/reperfusion in cardiac surgery with cardiopulmonary bypass (CPB) on nitric oxide (NO) levels of peripheral blood, venous levels of NO2- and NO3- were measured at multiple time-points before, during, and after CPB by means of high-pressure liquid chromatograph to reflect NO concentration indirectly in 20 patients. The results showed there was a linear regression between the decreased trend of NO release at the period of peri-CPB is related to the endothelial cell activation caused by ischemia/reperfusion at the same time. Therefore it is necessary to explore the regulation and action of NO release during systemic inflammatory response procedure in CPB.
authors.affiliation: Division of Cardiothoracic Surgery, First Affiliated Hospital, Changdu.
authors.forename: X
authors.initials: X
authors.lastname: Xiao
authors.forename: M
authors.initials: M
authors.lastname: Liang
authors.forename: Q
authors.initials: Q
authors.lastname: Yu
authors.forename: Y
authors.initials: Y
authors.lastname: Huang
authors.forename: P
authors.initials: P
authors.lastname: Zhou
authors.forename: X
authors.initials: X
authors.lastname: Zhang
authors.forename: W
authors.initials: W
authors.lastname: Zeng
authors.forename: Z
authors.initials: Z
authors.lastname: Tian
mesh_terms: D000328:Adult; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects; D006801:Humans; D008297:Male; D015428:Myocardial Reperfusion Injury / Q000097:blood* / Q000209:etiology; D009569:Nitric Oxide / Q000097:blood*
chemical_list: D009569:Nitric Oxide