title: A new examination for both biliary and gastrointestinal function after pancreatobiliary surgery--single-isotope two-day method.
abstract: OBJECTIVE
  There are no established tests for both biliary and gastrointestinal function after pancreatobiliary surgery. In this study, mixing of ingested food with bile after long-term postoperative period was evaluated.
  
  
  METHODS
  Sixteen patients having undergone Imanaga pancreatoduodenectomy (postoperative years = 6.2 +/- 2.0) were evaluated concerning physiologic function of biliary tract and residual stomach using gastric emptying and hepatobiliary scintigraphy.
  
  
  RESULTS
  At least 24 months after Imanaga pancreatoduodenectomy, postoperative patients had reached 95.8 +/- 4.9% of the pre-illness bodyweight. Gastric emptying half-time (GET1/2) ranged from 9-147 min (mean: 60.6 +/- 35.0). The time of bile excretion from liver to jejunum ranged from 5-45 min (mean: 11.3 +/- 7.8). Asynchrony time ranged from -5-40 min (mean: 11.3 +/- 7.8). There was no significant correlation between GET1/2 and recovery of bodyweight (r = -0.042, P = 0.8809). Similarly, there was no significant correlation between the time of bile excretion and recovery of bodyweight (r = 0.042, P = 0.8791). On the other hand, asynchrony time had a significant inverse correlation with recovery of bodyweight (r = -0.590, P = 0.0146).
  
  
  CONCLUSIONS
  Single-isotope two-day method is an original and useful technique to evaluate biliary and gastrointestinal physiologic function after long-term postoperative period.
authors.affiliation: Department of Surgery, Toyama Prefectural Central Hospital, Japan. YIB03163@niftyserve.or.jp
authors.forename: T
authors.initials: T
authors.lastname: Sato
authors.forename: K
authors.initials: K
authors.lastname: Konishi
authors.forename: K
authors.initials: K
authors.lastname: Yabushita
authors.forename: H
authors.initials: H
authors.lastname: Kimura
authors.forename: K
authors.initials: K
authors.lastname: Maeda
authors.forename: M
authors.initials: M
authors.lastname: Tsuji
authors.forename: K
authors.initials: K
authors.lastname: Kinuya
authors.forename: K
authors.initials: K
authors.lastname: Nakajima
mesh_terms: D001646:Bile / Q000378:metabolism; D001659:Biliary Tract / Q000000981:diagnostic imaging* / Q000502:physiology; D003287:Contrast Media; D004064:Digestive System / Q000000981:diagnostic imaging*; D004068:Digestive System Physiological Phenomena; D019786:Gadolinium DTPA; D005746:Gastric Emptying / Q000502:physiology*; D006801:Humans; D016577:Pancreaticoduodenectomy; D011877:Radionuclide Imaging; D013997:Time Factors
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA