[Invasive aspergillosis in two hematological patients].
We present two cases of invasive aspergillosis in patients with acute myeloid leukemia. In neutropenic patients with antibiotic resistent fever, without specific symptoms or signs, invasive aspergillosis should be considered. Diagnostic approaches such as X-ray/CT-scan of the thorax and sinuses, relevant cultures and antigen detection should be performed. Due to diagnostic difficulties and the rapid progression of the infection empirical antifungal therapy should be given. During subsequent neutropenic episodes prophylactic antifungal therapy can possibly preempt recurrence.
Rask
C U
CU
Arhus Universitetshospital, haematologisk afdeling B. c.rask@dadlnet.dk
Peterslund
N A
NA
D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage; D001228:Aspergillosis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000276:immunology / Q000382:microbiology*; D008172:Lung Diseases, Fungal / Q000000981:diagnostic imaging* / Q000209:etiology / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000150:complications / Q000276:immunology / Q000382:microbiology*; D009894:Opportunistic Infections / Q000276:immunology / Q000382:microbiology*; D011859:Radiography
D000935:Antifungal Agents