Relationship between motor and language activation using fMRI.
The authors examined laterality ratios (i.e., [L-R]/[L+R]) from functional MRI (fMRI) scans obtained in 12 healthy volunteers during unimanual left- and right-hand finger movements and during a verb generation language task. The language and right-hand motor asymmetry ratios were correlated (rho = 0.71, p = 0.005) as were the left- and right-hand ratios (rho = -0.68, p = 0.008). Subjects with greater relative left hemisphere lateralization of language exhibit greater relative unilateral hemisphere activation during right-hand movements.
Loring
D W
DW
Department of Neurology, Medical College of Georgia, Augusta 30912-3275, USA.
Meador
K J
KJ
Allison
J D
JD
Wright
J C
JC
D000328:Adult; D001931:Brain Mapping; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007802:Language; D008279:Magnetic Resonance Imaging; D008297:Male; D009044:Motor Cortex / Q000033:anatomy & histology* / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*