[The mutual benefit role of pancreas and liver in combined transplantation].
We study observed the mutual benefits of pancreas and liver in combined hepaticopancreatic transplantation in rats. The result indicated that pancreas, when transplanted with liver, could survive for a significantly longer time (13.4 +/- 1.01 days) than it transplanted alone (9.2 +/- 1.14 days) (P < 0.05). The interstitial rejection was mild and its rejection grade was significantly different from that of pancreas transplanted alone (P < 0.05, chi 2 test). The liver, when transplanted with pancreas, regenerated with strong competence and contact structure morphologically compared with liver transplanted alone. We concluded that pancreas could be immunologically protected against rejection and liver can be nutritionalized by pancreas in combined pancreas and liver transplantation.
Qiao
H
H
Department of Surgery, Peking Union Medical College Hospital, Beijing.
Zhu
Y
Y
Jiang
H
H
D000818:Animals; D016031:Liver Transplantation; D008297:Male; D016035:Pancreas Transplantation; D051381:Rats; D011917:Rats, Inbred Lew; D017207:Rats, Sprague-Dawley; D017208:Rats, Wistar; D014181:Transplantation Immunology