title: The many routes of bacterial transfer RNAs after aminoacylation.
abstract: Subsequent to their aminoacylation, tRNAs are subject to specific maturation and/or correction processes. Aminoacylated tRNAs ready for use in translation are then specifically channelled to the ribosomal A or P sites. Structural and biochemical studies have opened the way towards furthering our understanding of these routes to the ribosome, which involve a strict distinction between initiator and elongator tRNAs.
authors.affiliation: Laboratoire de Biochimie, UMR 7654, Ecole Polytechnique-CNRS, Palaiseau cedex, F-91128, France. blanquet@coli.polytechnique.fr
authors.forename: S
authors.initials: S
authors.lastname: Blanquet
authors.forename: Y
authors.initials: Y
authors.lastname: Mechulam
authors.forename: E
authors.initials: E
authors.lastname: Schmitt
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D000604:Amino Acyl-tRNA Synthetases / Q000378:metabolism; D001426:Bacterial Proteins / Q000378:metabolism; D004952:Esters / Q000378:metabolism; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D010445:Peptide Elongation Factors / Q000378:metabolism; D010448:Peptide Initiation Factors / Q000378:metabolism; D014176:Protein Biosynthesis; D011487:Protein Conformation; D012323:RNA Processing, Post-Transcriptional; D012329:RNA, Bacterial / Q000378:metabolism*; D012346:RNA, Transfer, Amino Acyl / Q000378:metabolism*; D012270:Ribosomes / Q000378:metabolism
chemical_list: D000596:Amino Acids; D001426:Bacterial Proteins; D004952:Esters; D010445:Peptide Elongation Factors; D010448:Peptide Initiation Factors; D012329:RNA, Bacterial; D012346:RNA, Transfer, Amino Acyl; D000604:Amino Acyl-tRNA Synthetases