title: The effects of a unilateral ultrasound-guided renal biopsy on renal function in healthy sedated cats.
abstract: Complications of renal biopsies are well documented except for the change in renal function after a biopsy. Eighteen healthy, adult cats were divided into two groups (n = 9 cats/group). For the measurement of global and split renal function, Group 1 used the renal uptake of 99mTc-DTPA and Group 2 used the renal uptake of 99mTc-MAG3. Scintigraphic data were collected on days (-4), (-3), 0, 1, 2, and 4 post renal biopsy. Using ultrasound guidance, biopsies were taken from the right renal cortex on dO, before acquiring scintigraphic images. P - values less than 0.10 were considered significant due to the limited number of observations. The only statistically significant change (p = 0.08) in global renal function detected was by day following a unilateral renal biopsy. Cats imaged using 99mTc-MAG3 had discernible liver activity. A unilateral, ultrasound guided renal biopsy has minimal effect on renal function in normal, healthy sedated cats.
authors.affiliation: Department of Veterinary Clinical Sciences, Oklahoma State University, Stillwater 74078, USA.
authors.forename: W T
authors.initials: WT
authors.lastname: Drost
authors.forename: G A
authors.initials: GA
authors.lastname: Henry
authors.forename: J H
authors.initials: JH
authors.lastname: Meinkoth
authors.forename: J P
authors.initials: JP
authors.lastname: Woods
authors.forename: M E
authors.initials: ME
authors.lastname: Payton
authors.forename: C
authors.initials: C
authors.lastname: Rodebush
mesh_terms: D000778:Anesthetics, Dissociative / Q000008:administration & dosage; D000818:Animals; D001706:Biopsy / Q000009:adverse effects / Q000662:veterinary*; D002415:Cats / Q000033:anatomy & histology*; D016292:Procedural Sedation; D005260:Female; D007649:Ketamine / Q000008:administration & dosage; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology; D007672:Kidney Cortex / Q000000981:diagnostic imaging / Q000473:pathology; D008099:Liver / Q000000981:diagnostic imaging; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D011897:Random Allocation; D017263:Technetium Tc 99m Mertiatide; D016284:Technetium Tc 99m Pentetate; D018084:Ultrasonography, Interventional / Q000662:veterinary*
chemical_list: D000778:Anesthetics, Dissociative; D019275:Radiopharmaceuticals; D017263:Technetium Tc 99m Mertiatide; D007649:Ketamine; D016284:Technetium Tc 99m Pentetate