title: Malaria and stroke. Case report.
abstract: Malaria is a parasitic disease with high prevalence in several regions of the world. Infestation by Plasmodium faciparum can, in some cases, affect the central nervous system producing encephalitis resulting in death or neurological sequelae. The mechanisms involved in the pathophysiology of the cerebral lesion are not totally clear and there are currently two theories (mechanical and humoral) concerning this. We report a case of malaria with an atypical evolution, with a stroke lesion in the territory of the middle cerebral artery, with no association with encephalitis. We conclude that the mechanical theory is the one applicable to this patient.
authors.affiliation: Division of Cerebrovascular Diseases, Universidade Federal de São Paulo-Escola Paulista de Medicina (UNIFESP-EPM), Brazil. jfleopo@ibm.net
authors.forename: J F
authors.initials: JF
authors.lastname: Leopoldino
authors.forename: M M
authors.initials: MM
authors.lastname: Fukujima
authors.forename: A A
authors.initials: AA
authors.lastname: Gabbai
mesh_terms: D000328:Adult; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use; D006801:Humans; D016779:Malaria, Cerebral / Q000150:complications / Q000188:drug therapy; D016778:Malaria, Falciparum / Q000150:complications* / Q000188:drug therapy; D008297:Male; D010963:Plasmodium falciparum; D012307:Risk Factors; D020521:Stroke / Q000469:parasitology*
chemical_list: D000962:Antimalarials