title: [Detection of interleukin-2 receptor in patients with idiopathic thrombocytopenic purpura].
abstract: Using ELISA and indirect fluorescent antibody techniques(IFAT), the serum soluble inter-leukin-2 receptor(sIL-2R) and membrane IL-2R (mIL-2R) on lymphocyte cells induced by phyto-hemagglutinin (PHA) were studied in patients with idiopathic thrombocytopenic purpura (ITP). The results showed that the level of sIL-2R increased significantly before treatment and decreased after treatment; the percentages of mIL-2R induced by PHA decreased. There was no correlation between the level of serum sIL-2R and that of mIL-2R. Our observations suggest that increased level of serum sIL-2R in ITP patients may be one of causes evoking cellular immunological abnormalities.
authors.affiliation: Department of Hematology Xiagya Hospital, Changsha.
authors.forename: B
authors.initials: B
authors.lastname: Tan
authors.forename: X
authors.initials: X
authors.lastname: Zhao
authors.forename: C
authors.initials: C
authors.lastname: Yin
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy / Q000276:immunology*; D015375:Receptors, Interleukin-2 / Q000097:blood*
chemical_list: D005938:Glucocorticoids; D015375:Receptors, Interleukin-2