Actin-myosin interaction.
Recent advances in the study of muscle physiology was made possible by the application of novel experimental techniques including in vitro motility assay, molecular biology, and X-ray crystallography. A similar approach was successfully applied in studying the properties of cardiac actin-myosin interaction. Implication in clinical cardiology is also reviewed.
Sugiura
S
S
Department of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Japan. sugiura-2im@h.u-tokyo.ac.jp
D000199:Actins / Q000235:genetics / Q000378:metabolism*; D018360:Crystallography, X-Ray; D006331:Heart Diseases / Q000235:genetics / Q000378:metabolism; D006801:Humans; D008856:Microscopy, Fluorescence; D009154:Mutation; D009200:Myocardial Contraction; D009206:Myocardium / Q000378:metabolism*; D009218:Myosins / Q000235:genetics / Q000378:metabolism*; D020033:Protein Isoforms / Q000378:metabolism
D000199:Actins; D020033:Protein Isoforms; D009218:Myosins