[Screening of antiviral agents from medicinal herbs by means of Hepadnaviruses models].
The antiviral study of 21 Chinese medicinal herbs was carried out in vitro and in vivo. The extracts of phyllanthus urinarin and polygonum cuspidatum exhibite obvious effects on duck hepatitis B virus and human hepatitis B virus, while the extract of Eclipta alba showed limited inhibition on HBV DAN polymerase.
Mi
Z
Z
Institute of Microbiology and Epidemiology, Academy of Military Sciences, Beijing.
Chen
H
H
Zhang
X
X
Li
Z
Z
Chen
W
W
Shao
X
X
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D002478:Cells, Cultured; D004279:DNA, Viral / Q000187:drug effects; D004259:DNA-Directed DNA Polymerase / Q000378:metabolism; D004353:Drug Evaluation, Preclinical; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D019665:Euphorbiaceae; D018347:Hepadnaviridae Infections / Q000821:virology; D015611:Hepatitis B Virus, Duck / Q000187:drug effects*; D006515:Hepatitis B virus / Q000187:drug effects*; D006801:Humans; D008099:Liver / Q000473:pathology / Q000821:virology*
D000998:Antiviral Agents; D004279:DNA, Viral; D004365:Drugs, Chinese Herbal; D004259:DNA-Directed DNA Polymerase