Gamma Knife radiosurgery for pituitary adenomas.
Ninety-two patients with pituitary adenomas have been treated during the last 5 years. Sixty-three of these patients had more than 6 months follow-up, and they form the basis of this report. Eighteen had non-functioning adenomas (NFA), and 36 had functioning adenomas (FA). The mean marginal dose was 22.5 Gy (NFA 19.5 Gy, FA 23.9 Gy). Control of tumor growth was achieved in 92%. A significant decrease of excessive hormone production was seen in 75.6%, and the endocrinopathy normalization rate was 26.7%. Post-radiosurgical complications were seen in 4.7%.
Hayashi
M
M
Department of Neurosurgery, Neurological Institute, Tokyo Women's Medical University, Tokyo, Japan. mhayashi@rr.iij4u.or.jp
Izawa
M
M
Hiyama
H
H
Nakamura
S
S
Atsuchi
S
S
Sato
H
H
Nakaya
K
K
Sasaki
K
K
Ochiai
T
T
Kubo
O
O
Hori
T
T
Takakura
K
K
D000172:Acromegaly / Q000209:etiology; D000236:Adenoma / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D003480:Cushing Syndrome / Q000209:etiology; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D015175:Prolactinoma / Q000601:surgery; D016634:Radiosurgery; D012189:Retrospective Studies; D013997:Time Factors; D014794:Visual Fields