title: MRA in patients with cerebrovascular disease. Considerations of clinical effectiveness.
abstract: OBJECTIVE
  To establish in which clinical contexts cerebral MR angiography (MRA) is routinely carried out in a neurological university department and to describe its clinical impact.
  
  
  METHODS
  Medical records, reports of findings and documentation of imaging examinations carried out in all 69 patients referred to the Department of Radiology from the Department of Neurology between 1995 and 1998 for cerebral MRA were evaluated. The clinical impact of all imaging findings was assessed on the basis of the medical records.
  
  
  RESULTS
  Circulatory disturbances in the vertebrobasilar arteries (n = 34) were the most frequent indication for investigation. MRA followed CT or duplex sonography in 66 of the 69 patients with a mean delay of 8 days. MRA was considered diagnostically inferior to conventional MR in 11 cases, comparable in 30 and superior in 25. Comparing MRA and duplex sonography, the corresponding figures were 12, 29 and 23. In retrospect, 56 MRAs were judged unnecessary.
  
  
  CONCLUSIONS
  Controlled clinical studies on optimal use of MRA are needed to avoid wasting resources and to exploit the method's full diagnostic potential in appropriate cases.
authors.affiliation: Department of Radiology, University Hospital, Cologne, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Krug
authors.forename: K
authors.initials: K
authors.lastname: Terstegge
authors.forename: M
authors.initials: M
authors.lastname: Neveling
authors.forename: M
authors.initials: M
authors.lastname: Zähringer
authors.forename: H
authors.initials: H
authors.lastname: Kugel
authors.forename: K
authors.initials: K
authors.lastname: Lackner
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002536:Cerebral Arteries / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000175:diagnosis*; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed