Subcutaneous sarcoidosis associated with vitiligo, pernicious anaemia and autoimmune thyroiditis.
We report a patient with pernicious anaemia, primary autoimmune hypothyroidism and vitiligo, who presented with subcutaneous nodules. Histopathology of the nodules revealed noncaseating granulomas, consistent with a diagnosis of sarcoidosis. Mild pulmonary sarcoid was also detected. Although an association between sarcoidosis and other autoimmune diseases is well-recognized, the presence of the particular autoimmune diseases in our patient and the involvement of subcutaneous fat in the sarcoidal inflammation, appears to represent a most unusual clinicopathological combination.
Barnadas
M A
MA
Department of Dermatology; Respiratory Medicine, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Rodríguez-Arias
J M
JM
Alomar
A
A
D000328:Adult; D000752:Anemia, Pernicious / Q000150:complications*; D005260:Female; D006801:Humans; D012507:Sarcoidosis / Q000150:complications*; D012871:Skin Diseases / Q000150:complications*; D013967:Thyroiditis, Autoimmune / Q000150:complications*; D014820:Vitiligo / Q000150:complications*