title: Predictive values of the ICT Tuberculosis test for the routine diagnosis of tuberculosis in Madagascar.
abstract: The rapid commercialised ICT Tuberculosis test has been tested in Madagascar for the diagnosis of smear-positive pulmonary (SM+) and extra-pulmonary tuberculosis (EPT), using microscopy, culture and histopathology as reference tests. Specificity was 83.3% and sensitivity 68.2% for SM+ patients and 65.2% for EPT patients. With a prevalence of 22.2% for SM+ patients and 52.4% for confirmed EPT among consulting patients in the National Reference Laboratory, the ICT Tuberculosis assay was not sufficiently predictive for application in the tuberculosis control programme.
authors.affiliation: Institut Pasteur de Madagascar, Tuberculosis National Reference Laboratory, Antananarivo. vrasolof@pasteur.mg
authors.forename: V
authors.initials: V
authors.lastname: Rasolofo
authors.forename: T
authors.initials: T
authors.lastname: Rasolonavalona
authors.forename: H
authors.initials: H
authors.lastname: Ramarokoto
authors.forename: S
authors.initials: S
authors.lastname: Chanteau
mesh_terms: D003906:Developing Countries; D005260:Female; D006801:Humans; D008270:Madagascar; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D012680:Sensitivity and Specificity; D012698:Serologic Tests / Q000379:methods; D014374:Tuberculin Test; D014376:Tuberculosis / Q000175:diagnosis*