title: Comparison of two implantation sites for testing intraosseous biocompatibility.
abstract: The purpose of this study was to compare two implantation sites--the mandible and the femur of the rabbit--for testing in vivo intraosseous biocompatility. Twenty-two new Zealand rabbits were anesthetized, and the mandibular and femur bones were exposed. A hybrid glass ionomer cement or zinc oxide eugenol cement was loaded into silicone carriers and inserted into the two bones after drilling the two cortical plates. Eleven rabbits were killed 4 wk after implantation, and 11 rabbits were killed after 12 wk. The mandibles and femurs were prepared using standard histological procedures; tissue reactions were graded from none to severe. At 4 wk, no statistically significant difference was found between the two implantation sites. After 12 weeks, bone healing was statistically better in the mandible than in the femur. The mandible seems to be a better implantation site in the case of intraosseous implantation tests. The intraosseous biocompatibility of Vitremer was similar at 4 wk and superior at 12 wk to that of Super-EBA.
authors.affiliation: Department of Restorative Dentistry, Marseilles Dental School, France.
authors.forename: H
authors.initials: H
authors.lastname: Tassery
authors.forename: W J
authors.initials: WJ
authors.lastname: Pertot
authors.forename: J
authors.initials: J
authors.lastname: Camps
authors.forename: J P
authors.initials: JP
authors.lastname: Proust
authors.forename: J
authors.initials: J
authors.lastname: Déjou
mesh_terms: D000818:Animals; D003188:Composite Resins; D003758:Dental Implantation, Endosseous; D017220:Dentin-Bonding Agents; D005269:Femur; D005899:Glass Ionomer Cements; D020007:Implants, Experimental; D008334:Mandible; D008422:Materials Testing; D011817:Rabbits; D012387:Root Canal Filling Materials
chemical_list: D003188:Composite Resins; D017220:Dentin-Bonding Agents; D005899:Glass Ionomer Cements; D012387:Root Canal Filling Materials; C084550:Vitremer; C084074:Super EBA