title: Antiphospholipid antibodies and in vitro fertilization success: a meta-analysis.
abstract: OBJECTIVE
  To evaluate whether the presence of antiphospholipid antibodies among women undergoing IVF affects the likelihood of IVF success.
  
  
  METHODS
  A meta-analysis of seven eligible studies on antiphospholipid antibodies and IVF outcome.
  
  
  METHODS
  Odds ratios (ORs) and 95% confidence intervals (CIs) of an association between the presence of antiphospholipid antibodies and both clinical pregnancy and live birth from IVF.
  
  
  RESULTS
  There was no significant association between antiphospholipid abnormalities and either clinical pregnancy (OR 0.99; 95% CI 0.64-1.53) or live birth (OR 1.07; 95% CI 0.66-1.75) in IVF patients.
  
  
  CONCLUSIONS
  The measurement of antiphospholipid antibodies is not warranted in patients undergoing IVF.
authors.affiliation: Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. mdhornstei@bics.bwh.harvard.edu
authors.forename: M D
authors.initials: MD
authors.lastname: Hornstein
authors.forename: O K
authors.initials: OK
authors.lastname: Davis
authors.forename: J B
authors.initials: JB
authors.lastname: Massey
authors.forename: R J
authors.initials: RJ
authors.lastname: Paulson
authors.forename: J A
authors.initials: JA
authors.lastname: Collins
mesh_terms: D001323:Autoantibodies / Q000097:blood*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D010743:Phospholipids / Q000276:immunology*; D011247:Pregnancy / Q000276:immunology*; D018873:Pregnancy Rate
chemical_list: D001323:Autoantibodies; D010743:Phospholipids