title: alpha-Substituted N-(sulfonamido)alkyl-beta-aminotetralins: potent and selective neuropeptide Y Y5 receptor antagonists.
authors.affiliation: Drug Discovery, The R. W. Johnson Pharmaceutical Research Institute, Welsh and McKean Roads, Spring House, Pennsylvania 19477, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Youngman
authors.forename: J J
authors.initials: JJ
authors.lastname: McNally
authors.forename: T W
authors.initials: TW
authors.lastname: Lovenberg
authors.forename: A B
authors.initials: AB
authors.lastname: Reitz
authors.forename: N M
authors.initials: NM
authors.lastname: Willard
authors.forename: D H
authors.initials: DH
authors.lastname: Nepomuceno
authors.forename: S J
authors.initials: SJ
authors.lastname: Wilson
authors.forename: J J
authors.initials: JJ
authors.lastname: Crooke
authors.forename: D
authors.initials: D
authors.lastname: Rosenthal
authors.forename: A H
authors.initials: AH
authors.lastname: Vaidya
authors.forename: S L
authors.initials: SL
authors.lastname: Dax
mesh_terms: D002460:Cell Line; D006801:Humans; D011869:Radioligand Assay; D017476:Receptors, Neuropeptide Y / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013764:Tetrahydronaphthalenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism; D014162:Transfection
chemical_list: D017476:Receptors, Neuropeptide Y; D013449:Sulfonamides; D013764:Tetrahydronaphthalenes; C100568:neuropeptide Y5 receptor