Prevention of venous thromboembolism: adherence to the 1995 American College of Chest Physicians consensus guidelines for surgical patients.
BACKGROUND
The American College of Chest Physicians addressed the dilemma of identifying optimal therapy for venous thromboembolism (VTE) prophylaxis and published their Fourth Consensus Conference on Antithrombotic Therapy in 1995, with recommendations for prophylactic therapy. Despite these recommendations, appropriate VTE prophylactic therapy is underused.


OBJECTIVE
To examine routine practices in the prevention of VTE in high-risk surgical patients and to determine the extent of adoption of grade A prophylactic therapies as recommended by the American College of Chest Physicians.


METHODS
Retrospective medical record review in 10 teaching or community-based hospitals located in the United States. Medical charts of 1907 patients were randomly selected for review from the population of patients who underwent high-risk major abdominal surgery, total hip replacement, hip fracture repair, or total knee replacement between January 1, 1996, and February 28, 1997.


RESULTS
Of 1907 patients, VTE prophylaxis was used in 89.3%; use was 93.7% in each of the 3 orthopedic surgery groups and 75.2% in the high-risk major abdominal surgery group. The percentage of patients receiving grade A therapy was highest in the hip replacement group (84.3%) vs. the other groups (knee replacement, 75.9%; hip fracture repair, 45.2%; abdominal surgery, 50.3%).


CONCLUSIONS
The use of grade A prophylaxis was related to the type of surgery, with the highest use seen in total hip replacement and the lowest in hip fracture repair. One in 4 patients who underwent high-risk major abdominal surgeries failed to receive any form of VTE prophylaxis. Publication of consensus statements alone may be insufficient to ensure the incorporation of important new clinical information into routine practice.
Stratton
M A
MA
College of Pharmacy, University of Houston, and Hermann Hospital, TX 77030, USA. mstratton@uh.edu
Anderson
F A
FA
Bussey
H I
HI
Caprini
J
J
Comerota
A
A
Haines
S T
ST
Hawkins
D W
DW
O'Connell
M B
MB
Smith
R C
RC
Stringer
K A
KA
D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D003245:Consensus Statements as Topic; D017984:Enoxaparin / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000009:adverse effects*; D017410:Practice Guidelines as Topic / Q000592:standards*; D011655:Pulmonary Embolism / Q000209:etiology / Q000517:prevention & control*; D015272:Pulmonary Medicine / Q000592:standards*; D011667:Pulmonary Veins / Q000187:drug effects*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014481:United States; D014859:Warfarin / Q000627:therapeutic use
D000925:Anticoagulants; D017984:Enoxaparin; D014859:Warfarin