Role of COX-2 inhibition on the formation and healing of gastric ulcers induced by indomethacin in the rat.
Godessart
N
N
Research Center, Almirall Prodesfarma, Barcelona, Spain.
Salcedo
C
C
Fernández
A G
AG
Palacios
J M
JM
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000633:toxicity*; D001241:Aspirin / Q000633:toxicity; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000008:administration & dosage / Q000494:pharmacology*; D004008:Diclofenac / Q000633:toxicity; D015232:Dinoprostone / Q000378:metabolism; D007213:Indomethacin / Q000008:administration & dosage / Q000633:toxicity*; D007527:Isoenzymes / Q000037:antagonists & inhibitors* / Q000494:pharmacology*; D020910:Ketorolac / Q000633:toxicity; D008297:Male; D009578:Nitrobenzenes / Q000008:administration & dosage / Q000494:pharmacology*; D011451:Prostaglandin-Endoperoxide Synthases / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D013276:Stomach Ulcer / Q000139:chemically induced* / Q000201:enzymology* / Q000473:pathology; D013449:Sulfonamides / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors; D014945:Wound Healing / Q000187:drug effects
D000894:Anti-Inflammatory Agents, Non-Steroidal; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D009578:Nitrobenzenes; D013449:Sulfonamides; C080955:N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide; D004008:Diclofenac; D051546:Cyclooxygenase 2; D011451:Prostaglandin-Endoperoxide Synthases; D015232:Dinoprostone; D001241:Aspirin; D007213:Indomethacin; D020910:Ketorolac