title: Inpatient opiate detoxification in Geneva: follow-up at 1 and 6 months.
abstract: The aim of this study was to identify predictors of treatment success and of relapse, 1 and 6 months after inpatient opiate detoxification in an 8-bed unit in Geneva. Of all 73 patients admitted between June 1994 and June 1995, a majority (73%) successfully finished opiate detoxification. Detoxification was performed mainly with methadone tapering; the average duration of hospitalisation was 15 days. Factors associated with treatment failure were: cocaine abuse, presence of legal problems, and short duration of hospital stay. After 1 month, 65% of the patients were using drugs (half of them were dependent again, half of them had used occasionally) and 35% were completely abstinent (21% when excluding those in residential treatment). Predictors of rapid relapse were cocaine abuse and little concern with own psychological situation at baseline. After 6 months, 50% were physically dependent again, 13% had lapsed occasionally, 37% were abstinent (28% when excluding those in residential treatment). Only high benzodiazepine use at baseline was associated with medium term abstinence. Addiction severity index composite scores had considerably improved between baseline and 6 months. Prevention of relapse to opiate use after inpatient detoxification, especially for those with a concurrent cocaine abuse, should be improved.
authors.affiliation: Division of Substance Abuse, Department of Psychiatry, University Hospital, Geneva, Switzerland. broers-barbara@diogenes.hcuge.ch
authors.forename: B
authors.initials: B
authors.lastname: Broers
authors.forename: F
authors.initials: F
authors.lastname: Giner
authors.forename: P
authors.initials: P
authors.lastname: Dumont
authors.forename: A
authors.initials: A
authors.lastname: Mino
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008658:Inactivation, Metabolic; D007902:Length of Stay; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D009294:Narcotics / Q000627:therapeutic use*; D009293:Opioid-Related Disorders / Q000378:metabolism / Q000523:psychology / Q000534:rehabilitation*; D011446:Prospective Studies; D012720:Severity of Illness Index; D013557:Switzerland; D016896:Treatment Outcome
chemical_list: D009294:Narcotics; D008691:Methadone