title: A family with cases of adult onset Still's disease and psoriatic arthritis.
abstract: Adult onset Still's disease is recognized as an adult variant of the systemic form of juvenile rheumatoid arthritis, whose disease-predisposition is still debated. On the other hand, the association between HLA subtypes and several groups of seronegative arthritis including psoriatic arthritis has been well documented. This report describes a family where adult onset Still's disease in a young man and psoriatic arthritis in his father were seen. Both patients were HLA-B39-positive, which was likely playing important pathogenic roles in the latter case. Clinical and immunological aspects of HLA-B39-related inflammatory diseases are also discussed.
authors.affiliation: Second Department of Internal Medicine, Hiroshima University School of Medicine.
authors.forename: H
authors.initials: H
authors.lastname: Maeda
authors.forename: F
authors.initials: F
authors.lastname: Konishi
authors.forename: K
authors.initials: K
authors.lastname: Hiyama
authors.forename: S
authors.initials: S
authors.lastname: Ishioka
authors.forename: M
authors.initials: M
authors.lastname: Yamakido
mesh_terms: D000328:Adult; D015535:Arthritis, Psoriatic / Q000276:immunology*; D015235:HLA-B Antigens / Q000097:blood*; D059946:HLA-B39 Antigen; D006801:Humans; D008297:Male; D009679:Nuclear Family; D016706:Still's Disease, Adult-Onset / Q000276:immunology*
chemical_list: D015235:HLA-B Antigens; D059946:HLA-B39 Antigen