title: Immunophilins: their properties and their potential role in therapeutic drug monitoring.
abstract: This article reviews recent developments in the immunophilin arena and the current state of knowledge about the biochemical properties of immunophilins. The role of immunophilin-binding assays is also explored with the conclusion that some of these immunosuppressive-drug-binding proteins may provide better assays for sirolimus and tacrolimus than current immunoassays.
authors.affiliation: Department of Laboratory Medicine, Children's National Medical Center, Washington, DC 20010, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: Soldin
mesh_terms: D000818:Animals; D016903:Drug Monitoring; D006801:Humans; D020104:Immunophilins / Q000378:metabolism*; D007166:Immunosuppressive Agents / Q000378:metabolism* / Q000627:therapeutic use; D008024:Ligands; D011955:Receptors, Drug / Q000378:metabolism
chemical_list: D007166:Immunosuppressive Agents; D008024:Ligands; D011955:Receptors, Drug; D020104:Immunophilins