Effect of gender on the progression of nondiabetic renal disease: a meta-analysis.
There is previously published evidence that male gender is associated with a more rapid rate of progression of nondiabetic chronic renal disease. However, some investigators have concluded that no such association exists. To help resolve this issue, a meta-analysis was performed using 68 studies that met defined criteria and contained a total of 11,345 patients to evaluate the effect of gender on the progression of nondiabetic chronic renal disease. The results indicate that men with chronic renal disease of various etiologies show a more rapid decline in renal function with time than do women.
Neugarten
Joel
J
Renal Division, Department of Medicine, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, New York.
Acharya
Anjali
A
Renal Division, Department of Medicine, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, New York.
Silbiger
Sharon R
SR
Renal Division, Department of Medicine, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, New York.
D000328:Adult; D002648:Child; D002908:Chronic Disease; D018450:Disease Progression; D005260:Female; D005922:Glomerulonephritis, IGA / Q000503:physiopathology; D015433:Glomerulonephritis, Membranous / Q000503:physiopathology; D006801:Humans; D007674:Kidney Diseases / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D016891:Polycystic Kidney, Autosomal Dominant / Q000503:physiopathology; D012044:Regression Analysis; D012727:Sex Characteristics