Nail alterations secondary to pactitaxel [corrected] therapy.
Docetaxel and pactitaxel [corrected] are the main drugs pertaining to the taxanes family. Nail alterations associated with docetaxel therapy are not a rare event, but they have rarely been reported secondary to paclitaxel therapy, probably because of its more recent use. We present two cases of onycholysis and nail discoloration secondary to paclitaxel therapy.
Almagro
M
M
Departments of Dermatology and Family Medicine, Hospital Juan Canalejo, Xubias de Arriba 84, 15006 La Coruña, Spain. Almagro@canalejo.org
Pozo
J D
JD
Garcia
J
J
Vasquez
A
A
Fonseca
E
E
D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy / Q000556:secondary; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009260:Nail Diseases / Q000139:chemically induced*; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D017239:Paclitaxel / Q000009:adverse effects*; D010859:Pigmentation Disorders / Q000139:chemically induced*
D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel