Carbamazepine-induced systemic lupus erythematosus presenting as cardiac tamponade.
Here we report the case of a patient who presented with acute cardiac tamponade due to drug-induced systemic lupus erythematosus (SLE). The patient had been treated for a seizure disorder with carbamazepine, a drug that has previously been demonstrated to cause SLE-like syndromes. Further serologic analysis demonstrated the likelihood of drug-induced SLE in this patient, with the rare presentation of cardiac tamponade.
Verma
S P
SP
Renal Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6144, USA. sunilv@att.net
Yunis
N
N
Lekos
A
A
Crausman
R S
RS
D000208:Acute Disease; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D002220:Carbamazepine / Q000009:adverse effects* / Q000627:therapeutic use; D002305:Cardiac Tamponade / Q000139:chemically induced* / Q000175:diagnosis; D003937:Diagnosis, Differential; D004829:Epilepsy, Generalized / Q000188:drug therapy*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged
D000927:Anticonvulsants; D002220:Carbamazepine