title: Radiographic assessment of disease progression in rheumatoid arthritis patients treated with methotrexate or minocycline.
abstract: Radiographic studies of methotrexate (MTX) treated and minocycline treated patients with rheumatoid arthritis (RA) are reviewed. A formal metaanalysis of publications of RA treated with MTX was undertaken at the time when MTX was used for patients with established RA. Thus the conclusions of that metaanalysis may not be applicable to patients treated with MTX earlier in the course of their disease. On the other hand, there are no sufficient data to conduct a formal metaanalysis of patients with RA treated with minocycline.
authors.affiliation: University of Alabama at Birmingham School of Medicine, 35294, USA. graciela.alarcon@ccc.uab.edu
authors.forename: G S
authors.initials: GS
authors.lastname: Alarcón
authors.forename: A A
authors.initials: AA
authors.lastname: Bartolucci
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008727:Methotrexate / Q000627:therapeutic use*; D008911:Minocycline / Q000627:therapeutic use*; D011859:Radiography; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D007166:Immunosuppressive Agents; D008911:Minocycline; D008727:Methotrexate