title: [Poor prognosis of osteosarcoma of pelvis; 39 years of registration by the Netherlands Commission on Bone Tumors].
abstract: OBJECTIVE
  To evaluate the results of treatment in patients with osteosarcoma of the pelvis.
  
  
  METHODS
  Retrospective.
  
  
  METHODS
  Sixty-five patients with pelvic osteosarcoma registered in the files of the Netherlands Committee on Bone Tumours over 1957-1995 were reviewed. Complete information was obtained on 62 cases: 27 males and 35 females, median age was 31 years (range: 12-83). Distant metastases were present in 11 patients (stage IIIB; 18%), while 50 patients had stage IIB osteosarcoma (81%) and 1 patient stage IB osteosarcoma (2%). The results of treatment and survival were determined.
  
  
  RESULTS
  Median survival was 14 months (2-177), the 5-year survival 15%. Distant metastases developed in 27 of 42 (64%) patients with curatively treated stage IIB osteosarcoma, with prolonged metastasis-free survival after chemotherapy treatment (p < 0.0012). Survival in patients with stage IIB pelvic osteosarcoma was better after surgical resection of the primary tumour than after no operation (p < 0.0054); (neo)adjuvant chemotherapy gave no longer survival than surgery alone (p < 0.083).
  
  
  CONCLUSIONS
  The prognosis of pelvic osteosarcoma was poor, despite modern multimodality treatment regimens, including surgical resection and chemotherapy.
authors.affiliation: Afd. Orthopedie, Academisch Ziekenhuis, Groningen.
authors.forename: S J
authors.initials: SJ
authors.lastname: Ham
authors.forename: H M
authors.initials: HM
authors.lastname: Kroon
authors.forename: H
authors.initials: H
authors.lastname: Schraffordt Koops
authors.forename: H J
authors.initials: HJ
authors.lastname: Hoekstra
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000401:mortality* / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009426:Netherlands / Q000453:epidemiology; D012516:Osteosarcoma / Q000401:mortality* / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery / Q000628:therapy*; D010384:Pelvic Bones / Q000601:surgery; D011379:Prognosis; D012042:Registries / Q000706:statistics & numerical data; D012189:Retrospective Studies; D015996:Survival Rate