title: [Changes of tissue oxygenation and relationship between oxygen delivery and consumption in patients with poor cardiac function undergoing valve replacement].
abstract: To study the relationship between oxygen delivery(DO2) and consumption(VO2) and tissue oxygenation in patients during cardiac valve replacement, DO2, VO2, arterial blood lactate (ABL) SvO2 were measured. The results showed a poor correlation between DO2 and VO2 and a normal tissue oxygenation before CPB. There was a good positive correlation between DO2 and VO2 within 20 h after the end of CPB(P < 0.01), and changes of ABL and SvO2 showed tissue hypoxia. The level of ABL in patients showing O2 supply-dependency was lower, and SvO2 was higher than those in 15 patients showing O2 supply-independency, respectively (P < 0.05). These data suggest that O2 supply-dependency was existed after the end of CPB, and there was a good correlation between O2 supply-dependency and ABL. It might not exclude tissue hypoxia in O2 supply-independency and normal level of SvO2.
authors.affiliation: Department of Anesthesiology, Second Affiliated Hospital, Hunan Medical University, Changsha.
authors.forename: L
authors.initials: L
authors.lastname: Liu
authors.forename: J
authors.initials: J
authors.lastname: Zhou
authors.forename: Q
authors.initials: Q
authors.lastname: Chen
mesh_terms: D000328:Adult; D002315:Cardiopulmonary Bypass; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006349:Heart Valve Diseases / Q000150:complications / Q000378:metabolism*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008943:Mitral Valve; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption
chemical_list: D010100:Oxygen