title: Hypotension and sensorineural hearing loss: a possible correlation.
abstract: A possible role of hypotension in the genesis of sudden or slowly developing sensorineural hearing loss has been outlined. In order to confirm this hypothesis, and to exclude other vascular risk factors, a prospective study was carried out within the "Brisighella Study", a wide and homogeneous group of subjects thoroughly examined from a metabolic and cardiovascular point of view. Among them, 20 participants aged 50 years or less (18 women, 2 men) with diastolic blood pressure < or = 60 mmHg and/or systolic blood pressure < or = 105 mmHg were selected and underwent otological and audiometric examinations. Patients with previous audiological, vestibular and otological diseases were excluded. The control group was represented by 100 subjects (60 women, 40 men), aged 50 years or less, randomly chosen from within a sample of the normal population in the same region. A statistically significant incidence of sensorineural hearing loss was recorded in the study group (7/20 subjects, all affected by low-frequency hearing loss), while hearing impairment was observed in only 3/100 participants in the control group. The mean values of the main metabolic parameters were normal. An alteration of the vasomotor system associated with a hypotensive condition could be responsible as a possible factor in the origin of a cochlear damage and the consequent sensorineural hearing loss.
authors.affiliation: Dipartimento di Scienze Chirurgiche ed Anestesiologiche, Universitá degli Studi di Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Pirodda
authors.forename: G G
authors.initials: GG
authors.lastname: Ferri
authors.forename: G C
authors.initials: GC
authors.lastname: Modugno
authors.forename: A
authors.initials: A
authors.lastname: Gaddi
mesh_terms: D000328:Adult; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D007022:Hypotension / Q000150:complications* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011897:Random Allocation; D012307:Risk Factors; D014666:Vasomotor System / Q000503:physiopathology