title: Why study vascular factors in glaucoma?
abstract: There is clinical and experimental evidence that both increased intraocular pressure and disturbed circulation are involved in the pathogenesis of glaucomatous damage. Among the many factors discussed, decreased blood pressure and vasospasm are the most important, and these factors may, at least in part, be therapeutically influenced. The basic underlying disorder might be a vascular dysfunction leading to local vasospasm and to systemic hypotension.
authors.affiliation: Clinic of Medicine, Regionalspital, Lachen SZ, Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Gasser
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity; D001794:Blood Pressure; D002908:Chronic Disease; D018450:Disease Progression; D005902:Glaucoma, Open-Angle / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure; D008833:Microcirculation; D009898:Optic Disk / Q000098:blood supply*; D016491:Peripheral Vascular Diseases / Q000503:physiopathology*; D012307:Risk Factors; D014661:Vasoconstriction