[Temporal regulation of gene expression].
Molecular biology gives a static--not a dynamic--vision of the mechanisms regulating gene expression. Genetics already gave to time a limited place in the explanation of living phenomena. Such a static vision is supported by the techniques--such as X-ray crystallography--used by the biologists. However time is an important parameter in the control of gene expression during the cellular response to external signals, during life and aging of organisms or even in the succession of living forms which takes place in evolution. Models are slowly moving, due to the eruption of new technologies giving access to the fast events which occur inside living cells. A new dynamic vision is progressively replacing the old one. The consequences of these changes on the form of the future biology remain still unknown.
Morange
M
M
UMR 8541, Département de Biologie, Ecole Normale Supérieure, Paris. morange@wotan.ens.fr
D000375:Aging; D000818:Animals; D005786:Gene Expression Regulation; D006801:Humans; D008957:Models, Genetic; D010507:Periodicity