Hantavirus Dobrava infection with pulmonary manifestation.
Dobrava virus infection was diagnosed serologically by enzyme-linked immunosorbent and immunofluorescence assays. To determine which hantavirus serotype was involved, sera were analyzed by a focus reduction neutralization test. The clinical data indicated that only pulmonary manifestation was present. Our data support the presence of Dobrava virus infection outside the Balkan region. In conclusion, a previously healthy adult with unexplained pulmonary perfusion failure should be investigated for hantavirus infection.
Mentel
R
R
Institute of Medical Microbiology, Ernst-Moritz-Arndt-University, Greifswald, Germany.
Bordihn
N
N
Wegner
U
U
Wendel
H
H
Niklasson
B
B
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005455:Fluorescent Antibody Technique; D005859:Germany, East; D006476:Orthohantavirus / Q000145:classification / Q000276:immunology*; D018804:Hantavirus Pulmonary Syndrome / Q000175:diagnosis* / Q000821:virology; D006801:Humans; D008297:Male
D000914:Antibodies, Viral