title: [Changes of blood supply from portal system after transcatheter arterial chemoembolization in huge hepatocellular carcinoma].
abstract: OBJECTIVE
  Blood supply changes of the portal venous system to the tumor mass before and after transcatheterarterial chemoembolization(TACE) in a series of 22 patients with huge hepatocellular carcinoma were monitored to study the necessity of intervention via portal vein.
  
  
  METHODS
  Twenty-two selected patients with huge hepatocellular carcinoma were enrolled in the study. Elscint double helical CT was used to scan liver during the maximum concentration of contrast medium in portal venous system. CT Angiography and MIP(Maximum Intensity Projection) were used to image formation of the portal venous system.
  
  
  RESULTS
  The technique of scan and image formation were excellent to evaluate the attribution of portal venous blood supply to HCC. The portal venous blood supply was mainly the tumor periphery distribution (P < 0.01). After treatment of TACE, the portal venous blood supply to tumor periphery increased significantly (P < 0.05), and some did appear signs of enriched blood supply around the tumor. Negative correlation between the degree of reduction in tumor and portal venous blood supply to the tumor periphery before TACE was evident.
  
  
  CONCLUSIONS
  The attribution of portal venous blood supply to HCC was in the tumor periphery, and regression of tumor after TACE was affected by portal venous blood supply to the tumor, thus it is reasonable to suggest interventional therapy via portal vein.
authors.affiliation: Department of Radiology, Second Affiliated Hospital, Hunan Medical University, Changsha.
authors.forename: H
authors.initials: H
authors.lastname: Liu
authors.forename: D
authors.initials: D
authors.lastname: Li
authors.forename: S
authors.initials: S
authors.lastname: Yang
authors.forename: Y
authors.initials: Y
authors.lastname: Wu
authors.forename: J
authors.initials: J
authors.lastname: Luo
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage; D016190:Carboplatin / Q000008:administration & dosage; D006528:Carcinoma, Hepatocellular / Q000098:blood supply* / Q000628:therapy; D016461:Chemoembolization, Therapeutic; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D008113:Liver Neoplasms / Q000098:blood supply* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011169:Portal Vein / Q000503:physiopathology; D011446:Prospective Studies
chemical_list: D000970:Antineoplastic Agents; D016190:Carboplatin