[Effect of protein deficiency in the female rat diet during pregnancy and lactation on the activity of the membrane and soluble forms of digestive enzymes in the offspring small intestine].
Protein deficiency in female rats diet during pregnancy and lactation resulted in deceleration of induction of sucrase both forms in the jejunum and ileum; in acceleration of induction of the maltase membrane from in the jejunum; and in suppression of the lactase membrane form in the ileum; in earlier forming of the adult-type distribution of activity of the membrane form of intestinal alkaline phosphatase and in a decrease in activity of the enzyme soluble form. The findings are corroborated by a suppression of activities of the membrane and soluble forms of the small intestine digestive enzymes in 30-day old rat pups fed with a control (adequate) ration starting 21 days after the birth.
Timofeeva
N M
NM
I. P. Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg, Russia.
Egorova
V V
VV
Nikitina
A A
AA
Iezuitova
N N
NN
Gordova
L A
LA
Gruzdkov
A A
AA
D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D018826:CD13 Antigens / Q000378:metabolism; D004150:Dipeptidases / Q000378:metabolism; D005260:Female; D006026:Glycoside Hydrolases / Q000378:metabolism; D007082:Ileum / Q000201:enzymology; D007421:Intestine, Small / Q000201:enzymology*; D007583:Jejunum / Q000201:enzymology; D043322:Lactase; D007774:Lactation / Q000502:physiology*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011488:Protein Deficiency; D051381:Rats; D017208:Rats, Wistar; D000520:alpha-Glucosidases / Q000378:metabolism; D043324:beta-Fructofuranosidase; D001616:beta-Galactosidase / Q000378:metabolism
D000469:Alkaline Phosphatase; D006026:Glycoside Hydrolases; D043322:Lactase; D000520:alpha-Glucosidases; D001616:beta-Galactosidase; D043324:beta-Fructofuranosidase; D018826:CD13 Antigens; D004150:Dipeptidases; C020825:cytosol non-specific dipeptidase