Astrocyte nitric oxide causes neuronal mitochondrial damage, but antioxidant release limits neuronal cell death.
Stone
R
R
Department of Neurochemistry, Institute of Neurology, Queen Square, London, England.
Stewart
V C
VC
Hurst
R D
RD
Clark
J B
JB
Heales
S J
SJ
D000818:Animals; D000831:Animals, Newborn; D001253:Astrocytes / Q000166:cytology / Q000502:physiology*; D016923:Cell Death; D002478:Cells, Cultured; D017077:Culture Media, Conditioned; D016895:Culture Media, Serum-Free; D005978:Glutathione / Q000378:metabolism*; D019803:Glutathione Disulfide / Q000378:metabolism; D007700:Kinetics; D008928:Mitochondria / Q000502:physiology / Q000648:ultrastructure*; D009474:Neurons / Q000166:cytology* / Q000502:physiology; D009569:Nitric Oxide / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar
D017077:Culture Media, Conditioned; D016895:Culture Media, Serum-Free; D009569:Nitric Oxide; D005978:Glutathione; D019803:Glutathione Disulfide