title: Serum inhibin B concentration in a prepubertal boy with gynecomastia and Peutz-Jeghers syndrome.
abstract: Gynecomastia in boys with Peutz-Jeghers syndrome and Sertoli cell tumors of gonadal origin results from increased estrogen production due to increased aromatase activity within the testicular tumor. We present a prepubertal boy with Peutz-Jeghers syndrome, gynecomastia and bilateral neoplastic Sertoli cell proliferation in whom the only abnormal hormonal profile was increased concentration of inhibin B and Pro-alpha C in serum.
authors.affiliation: División de Endocrinología, Hospital de Niños, R. Gutiérrez, Buenos Aires, Argentina.
authors.forename: I
authors.initials: I
authors.lastname: Bergadá
authors.forename: K
authors.initials: K
authors.lastname: Del Toro
authors.forename: O
authors.initials: O
authors.lastname: Katz
authors.forename: H
authors.initials: H
authors.lastname: Chemes
authors.forename: S
authors.initials: S
authors.lastname: Campo
mesh_terms: D001706:Biopsy; D002455:Cell Division; D002648:Child; D004958:Estradiol / Q000097:blood; D004970:Estrone / Q000031:analogs & derivatives / Q000097:blood; D005640:Follicle Stimulating Hormone / Q000097:blood; D006177:Gynecomastia / Q000097:blood* / Q000601:surgery; D006801:Humans; D007265:Inhibins / Q000097:blood*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010580:Peutz-Jeghers Syndrome / Q000097:blood*; D012707:Sertoli Cell Tumor / Q000473:pathology; D013736:Testicular Neoplasms / Q000473:pathology
chemical_list: C015856:estrone-3-glucuronide; D004970:Estrone; D004958:Estradiol; D007265:Inhibins; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone