[Study on hepatitis G virus infection].
OBJECTIVE
To find out the situation of HGV infection in Shandong Province, and to explore the relations between HGV infection and HCV or HBV infection.


METHODS
Enzyme linked immunosorbent assay (ELISA) was used to determine the serum anti-HGV in 1,082 patients with viral hepatitis, 77 patients with non A-E hepatitis and 361 blood donors.


RESULTS
53 patients whose serum anti-HGVs were positive (positive rate: 3.49%) were noticed. The anti-HGV positive rate (8.93%) in patients with Hepatitis C was remarkably higher than that (3.32%) in patients with Hepatitis B (chi 2 = 8.80, P < 0.01). The anti-HGV positive rate (4.82%) in patients with chronic hepatitis was significantly higher than that (0.79%) in patients with acute hepatitis (chi 2 = 10.79, P < 0.01). The anti-HGV positive rate (8.00%) in patients with severe hepatitis was obviously higher than that in patients with acute hepatitis (chi 2 = 10.23, P < 0.01).


CONCLUSIONS
The manifestations of HGV infection can be expressed as virus-carriers, subclinical infection or various clinical types. Patients with Hepatitis C were more subjective to be overlapped with HGV than the patients with Hepatitis B; moreover, HCV or HBV infection superinfected with HGV is associated with exacerbation of patients' condition and the formation of chronic infection.
Chen
X
X
Taishan Medical College, Taian.
Xuan
M
M
Wu
D
D
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002681:China / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D018067:Flaviviridae / Q000276:immunology; D006509:Hepatitis B / Q000097:blood; D006526:Hepatitis C / Q000097:blood; D006525:Hepatitis, Viral, Human / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015163:Superinfection / Q000097:blood
D000914:Antibodies, Viral