title: [A study of genetic epidemiology on child bronchial asthma].
abstract: OBJECTIVE
  To examine the relationship between child bronchial asthma and genetic fastor.
  
  
  METHODS
  A case-control study including 372 pedigree was carried out.
  
  
  RESULTS
  Child bronchial asthma had obvious familiar clustering (chi 2 = 24.8, P < 0.01). The prevalence rate of the first and the second degree relatives of proband was significally higher than that of the controls. The segregation ration of asthma was 0.14 (95% CL 0.098-0.18). The h2 of the first and second degree relatives of asthma were 78.18% and 55.02%, of which 83.64% for female and 73.48% for male.
  
  
  CONCLUSIONS
  The genetic model of asthma belonged to polygenetics. Genetic fastor was a main risk fastor for asthma, especially for female patients.
authors.affiliation: Anhui Medical University, Hefei.
authors.forename: G
authors.initials: G
authors.lastname: Tang
authors.forename: T
authors.initials: T
authors.lastname: Li
authors.forename: D
authors.initials: D
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000453:epidemiology* / Q000235:genetics*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007223:Infant; D008297:Male; D015995:Prevalence; D012307:Risk Factors