[Quantitive analysis of 5-hydroxytryptamine levels on edges of incised skin of rats].
To find index for early diagnosis of antemortem wound, the authors used the ICS analysis in a quantitive study of 5-hydroxytryptamine(5-HT) levels on rat's incised-skin antemortem wound in comparison with the postmortem wound inficted at various intervals. The results showed that the 5-HT increased significantly at 5 min, reached a peak at 15 min and decreased at 60 min on antemortem wounds. The 5-HT levels of antemortem groups were prominently high (more than 40%, P < 0.05) as compared with those of postmortem group and the levels of 5-HT on the wounds of postmortem groups were higher (35.77%, P < 0.05) than those of controls as well. The authors suggest that in the cases where the levels of 5-HT are as high as 40% on the edges of the injured skin, the injury should be considered an antemortem wound.
Lai
Y
Y
School of Forensic Medicine, Chengdu.
Liao
Z
Z
Liu
M
M
Wu
J
J
D000818:Animals; D005260:Female; D005554:Forensic Medicine; D008297:Male; D009391:Nephelometry and Turbidimetry / Q000379:methods; D011180:Postmortem Changes; D051381:Rats; D017208:Rats, Wistar; D012701:Serotonin / Q000032:analysis*; D012867:Skin / Q000737:chemistry* / Q000293:injuries*
D012701:Serotonin