Neurotoxic effects of endocrine disruptors.
Endocrine disrupting chemicals are a newly defined category of environmental contaminants that may affect animal and human populations by interfering with normal hormone action. There is substantial concern that these agents could have a range of subtle and long-lasting effects. Because of the sensitivity of the developing central nervous system to low levels of endogenous gonadal hormones during development, the central nervous system may be a target for the action of endocrine disrupting chemicals.
Laessig
S A
SA
Program in Toxicology, University of Maryland Medical System, Baltimore, USA. slaes001@umaryland.edu
McCarthy
M M
MM
Silbergeld
E K
EK
D000818:Animals; D002490:Central Nervous System / Q000187:drug effects* / Q000503:physiopathology*; D004703:Endocrine System / Q000187:drug effects* / Q000503:physiopathology; D004700:Endocrine System Diseases / Q000139:chemically induced*; D006801:Humans; D009498:Neurotoxins / Q000633:toxicity*
D009498:Neurotoxins