title: Sexual origins of placental dysfunction.
abstract: Severe placental dysfunction is much more common in pregnancies with a male than with a female fetus. Furthermore, the birthweight/placental weight ratio is increased in these pregnancies, consistent with fetal growth restriction, and is higher with a male fetus than with a female fetus. These observations of placental insufficiency may underlie the increased in-utero loss rate of male fetuses.
authors.forename: A
authors.initials: A
authors.lastname: Edwards
authors.forename: A
authors.initials: A
authors.lastname: Megens
authors.forename: M
authors.initials: M
authors.lastname: Peek
authors.forename: E M
authors.initials: EM
authors.lastname: Wallace
mesh_terms: D001724:Birth Weight; D005260:Female; D005317:Fetal Growth Retardation; D006801:Humans; D008297:Male; D009929:Organ Size; D010920:Placenta; D010927:Placental Insufficiency / Q000453:epidemiology*; D011247:Pregnancy; D012744:Sex Ratio