title: Diurnal preference, sleep habits, circadian sleep propensity and melatonin rhythm in healthy human subjects.
abstract: After 24-h sleep deprivation, 33 healthy young subjects entered the 10/20 min ultra-short sleep-wake schedule for 26 h. Melatonin rhythm was hourly assessed simultaneously. Results indicated that morning preference was significantly correlated with habitual sleep onset (r=-0.41, P=0.04), habitual sleep offset (r=-0.52, P=0.002), melatonin peak time (r=-0.36, P=0.04), and sleep propensity onset time (r=-0.36, P=0.04). The intervals between habitual sleep mid-point and melatonin peak time and between habitual sleep mid-point and sleep propensity onset time were significantly longer in morning-preference subjects than in evening-preference subjects (P<0.05). These findings suggest that the variance of diurnal preference may be related to differences in phase relations between habitual sleep timing and the circadian pacemaker.
authors.affiliation: Department of Psychophysiology, National Institute of Mental Health, NCNP, 1-7-3 Kohnodai, Ichikawa, Japan.
authors.forename: X
authors.initials: X
authors.lastname: Liu
authors.forename: M
authors.initials: M
authors.lastname: Uchiyama
authors.forename: K
authors.initials: K
authors.lastname: Shibui
authors.forename: K
authors.initials: K
authors.lastname: Kim
authors.forename: Y
authors.initials: Y
authors.lastname: Kudo
authors.forename: H
authors.initials: H
authors.lastname: Tagaya
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: M
authors.initials: M
authors.lastname: Okawa
mesh_terms: D000328:Adult; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008550:Melatonin / Q000097:blood* / Q000378:metabolism; D009043:Motor Activity; D012044:Regression Analysis; D012890:Sleep / Q000502:physiology*; D012892:Sleep Deprivation; D014851:Wakefulness
chemical_list: D008550:Melatonin