title: Heparin-induced hyperkalemia confirmed by drug rechallenge.
abstract: Subcutaneous heparin is commonly used as a prophylaxis against deep venous thrombosis in a wide variety of hospitalized patients. As with most medications, heparin has a significant side effect profile; heparin-induced hyperkalemia is an unusual but well described side effect. To increase awareness of heparin-induced hyperkalemia and of those patients at greatest risk, we present two cases of documented hyperkalemia induced by heparin and reconfirmed by drug rechallenge.
authors.affiliation: Department of Internal Medicine, University of Cincinnatti College of Medicine, Ohio, USA.
authors.forename: M P
authors.initials: MP
authors.lastname: Orlando
authors.forename: M E
authors.initials: ME
authors.lastname: Dillon
authors.forename: M W
authors.initials: MW
authors.lastname: O'Dell
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D005260:Female; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D006947:Hyperkalemia / Q000139:chemically induced* / Q000503:physiopathology; D008297:Male
chemical_list: D000925:Anticoagulants; D006493:Heparin