Sequential vidarabine infusion in the treatment of polyoma virus-associated acute haemorrhagic cystitis late after allogeneic bone marrow transplantation.
Late onset haemorrhagic cystitis (HC) occurs in 20-30% of allogeneic bone marrow transplant patients. Human polyomavirus BK (BKV) (or less frequently adenovirus) may be involved in the pathogenesis of viral HC and can represent a serious post-transplant complication. Diagnosis and treatment of viral HC can be difficult and has an uncertain outcome. We report the efficacy of sequential vidarabine in the treatment of a patient with severe BKV-associated HC, despite the delay in implementing therapy. Bone Marrow Transplantation (2000) 25, 319-320.
Vianelli
N
N
Institute of Hematology and Medical Oncology 'L&A Seràgnoli', University of Bologna, Italy.
Renga
M
M
Azzi
A
A
De Santis
R D
RD
Bandini
G
G
Tosi
P
P
Tura
S
S
D000208:Acute Disease; D019072:Antibiotic Prophylaxis; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D003556:Cystitis / Q000188:drug therapy* / Q000209:etiology / Q000821:virology*; D003967:Diarrhea; D017809:Fatal Outcome; D006417:Hematuria / Q000188:drug therapy / Q000209:etiology / Q000821:virology; D006470:Hemorrhage / Q000188:drug therapy / Q000209:etiology / Q000821:virology; D006801:Humans; D007951:Leukemia, Myeloid / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011120:Polyomavirus; D027601:Polyomavirus Infections; D013997:Time Factors; D014184:Transplantation, Homologous / Q000009:adverse effects; D014412:Tumor Virus Infections; D014740:Vidarabine / Q000008:administration & dosage*
D014740:Vidarabine