title: The intact retroviral Env glycoprotein of human foamy virus is a trimer.
abstract: Electron microscopy of negatively stained human foamy virus particles provides direct evidence for the trimeric nature of intact Env surface glycoproteins. Three-dimensional image reconstruction reveals that the Env trimer is a tapering spike 14 nm in length. The spikes were often arranged in hexagonal rings which shared adjacent Env trimers.
authors.affiliation: Structural Biology Programme, European Molecular Biology Laboratory, Heidelberg, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Wilk
authors.forename: F
authors.initials: F
authors.lastname: de Haas
authors.forename: A
authors.initials: A
authors.lastname: Wagner
authors.forename: T
authors.initials: T
authors.lastname: Rutten
authors.forename: S
authors.initials: S
authors.lastname: Fuller
authors.forename: R M
authors.initials: RM
authors.lastname: Flügel
authors.forename: M
authors.initials: M
authors.lastname: Löchelt
mesh_terms: D015686:Gene Products, env / Q000737:chemistry* / Q000648:ultrastructure; D006023:Glycoproteins / Q000737:chemistry / Q000648:ultrastructure; D006801:Humans; D011487:Protein Conformation; D012191:Retroviridae Proteins / Q000737:chemistry* / Q000648:ultrastructure; D016092:Spumavirus / Q000648:ultrastructure*
chemical_list: D015686:Gene Products, env; D006023:Glycoproteins; D012191:Retroviridae Proteins