[The anti-inflammatory effects of superoxide dismutase].
This paper reports the anti-inflammatory effects of superoxide dismutase (SOD) from pig blood on inflammatory animal models. The experimental results have shown that SOD has significant anti-inflammatory effects. It inhibited carrageenin-induced foot-edema and croton oil induced granulation tissue edema of rats. It also inhibited arthritis induced by egg serum and Freund's adjuvant in rats. The effects were significantly dose-dependent.
Xiong
Y
Y
Department of Pharmacology, School of Basic Medical Sciences, Chengdu.
Ye
S
S
Liang
Y
Y
Song
P
P
Zhou
S
S
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001169:Arthritis, Experimental / Q000188:drug therapy; D002351:Carrageenan; D003436:Croton Oil; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy*; D005534:Foot Diseases / Q000139:chemically induced / Q000188:drug therapy*; D005620:Freund's Adjuvant; D008297:Male; D010047:Ovalbumin; D051381:Rats; D017208:Rats, Wistar; D013482:Superoxide Dismutase / Q000627:therapeutic use*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D003436:Croton Oil; D002351:Carrageenan; D010047:Ovalbumin; D005620:Freund's Adjuvant; D013482:Superoxide Dismutase