title: Novel polycyclic guanidine alkaloids from two marine sponges of the genus Monanchora.
abstract: Two marine sponges of the genus Monanchora (Poecilosclerida, Crambeidae) have been found to contain new polycyclic guanidine alkaloids bearing the (5,6,8b)-triazaperhydroacenaphthylene skeleton. Their structures have been determined by detailed spectroscopic analysis. Dehydrobatzelladine C (1) has been isolated from M. arbuscula and crambescidins 359 (2) and 431 (3) from M. unguiculata. The chemotaxonomic implications of these findings are discussed.
authors.affiliation: Laboratory of Bio-organic Chemistry, Department of Organic Chemistry, Faculty of Sciences, CP160/07, University of Brussels, 50 Avenue F. Roosevelt, 1050 Brussels, Belgium. braekman@ulb.ac.be
authors.forename: J C
authors.initials: JC
authors.lastname: Braekman
authors.forename: D
authors.initials: D
authors.lastname: Daloze
authors.forename: R
authors.initials: R
authors.lastname: Tavares
authors.forename: E
authors.initials: E
authors.lastname: Hajdu
authors.forename: R W
authors.initials: RW
authors.lastname: Van Soest
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D000818:Animals; D006146:Guanidines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D011161:Porifera / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000470:Alkaloids; D006146:Guanidines