[The influence of different concentrations of hydrofluoric acid on blood calcium level in rats].
OBJECTIVE
To evaluate the effects of different concentration of hydrofluoric acid (HF) on local skin and calcium level of serum.


METHODS
SD rats were divided into two groups which were wounded by 20% and 40% percent of HF respectively. Samples of blood and wound tissue were harvested at different postburn time for the analysis of the calcium level of the serum and histological study.


RESULTS
It was found that twenty percent of HF was enough to cause a skin damage, and might bring about fatal hypocalcemia after a prolonged contact. High concentration of HF (40%) could cause deep tissue necrosis within a short time, and result in a fatal hypocalcemia within 24 hour even in the case of a small area injury.


CONCLUSIONS
It is important to treat the patient with HF injury as early as possible. Sufficient calcium must be applied guided by laboratory study in order to prevent the fatal hypocalcemia.
Wang
D
D
Department of Burns, Xiaoshan First People's Hospital.
Yang
Y
Y
Chen
Y
Y
D000818:Animals; D002057:Burns, Chemical / Q000378:metabolism*; D002118:Calcium / Q000097:blood*; D005260:Female; D006858:Hydrofluoric Acid; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors
D006858:Hydrofluoric Acid; D002118:Calcium