Scintigraphic evaluation of gastroesophageal reflux in newborns.
OBJECTIVE
This study was carried out to verify whether during neonatal stage gastroesophageal scintigraphy, may be useful not only to diagnose gastroesophageal reflux (GER), but also to detect pulmonary aspiration, at times responsible for respiratory symptoms frequently associated with GER.


METHODS
Gastroesophageal scintigraphy was performed on 50 newborns admitted to NICU of Brindisi in the last two years who presented symptoms as cyanosis, apnoea, bradycardia, laringeal stridor, wheezing, not related to respiratory or cardiac problems, but suspected to be clinical suggestive symptoms of "pathological" GER. After administration of 99mTC mixed with the usual meal formula, we obtained a recording period of 60-90 minutes and a later recording at 4 and 24 hours to document radioactive material in lungs.


RESULTS
Scintigraphy showed GER in 40/50 cases and despite frequent observation of respiratory symptoms (39/40 cases) in these newborns never radiation in pulmonary fields.


CONCLUSIONS
Our results could indicate that scintigraphy, noninvasive and low in radiation, may be considered effective and reliable to diagnose GER in newborns. The absence of radiation in pulmonary fields could indicate that respiratory symptoms frequently associated with GER could depend on involuntary mechanism of vagal type and not on pulmonary aspiration.
Latini
G
G
Unità di Terapia Intensiva e Patologia Neonatale, Azienda Ospedaliera A. Di Summa di Brindisi, Italia.
Del Vecchio
A
A
De Mitri
B
B
Giannuzzi
R
R
Presta
G
G
Quartulli
L
L
Rosati
E
E
Scarano
B
B
Pili
G
G
D001919:Bradycardia / Q000209:etiology / Q000517:prevention & control; D003490:Cyanosis / Q000209:etiology / Q000517:prevention & control; D005764:Gastroesophageal Reflux / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D007231:Infant, Newborn; D011015:Pneumonia, Aspiration / Q000209:etiology / Q000517:prevention & control; D011877:Radionuclide Imaging; D012135:Respiratory Sounds / Q000209:etiology