title: Left ventricular volume reduction for end-stage heart disease.
abstract: Partial left ventriculectomy (PLV) was recently introduced for end-stage dilated cardiomyopathy to improve ventricular function. Since November 1996 we have performed PLV in 14 patients; preoperatively 4 patients had idiopathic dilated cardiomyopathy and 10 had ischemic dilated cardiomyopathy. 57.1% of patients were in New York Heart Association functional Class IV. The mitral valve was replaced in 11 patients. Postoperative echocardiography showed a reduction of left end-diastolic diameter (55.4 +/- 5.4 mm) and an increase in forward ejection (cardiac index from 2.19 +/- 0.571 min/m2 to 2.67 +/- 0.931/min/m2). The 30-day mortality was 28.6% and 20-month survival was 57.2%. Only one patient was not in NYHA functional class due to postoperative progressive mitral incompetence. Prognostic factors should be identified to avoid early failure. However, even if the mortality rate for PLV high, this operation is a valid choice for the treatment of end-stage dilated cardiomyopathy.
authors.affiliation: Department of Cardiac Surgery, Azienda Ospedaliera Polo Universitario Luigi Sacco, Milan, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Vanelli
authors.forename: L
authors.initials: L
authors.lastname: Beretta
authors.forename: P M
authors.initials: PM
authors.lastname: Fundarò
authors.forename: C
authors.initials: C
authors.lastname: Carro
authors.forename: C
authors.initials: C
authors.lastname: Santoli
authors.forename: A
authors.initials: A
authors.lastname: Mangini
authors.forename: A M
authors.initials: AM
authors.lastname: Condemi
authors.forename: P
authors.initials: P
authors.lastname: Castelli
authors.forename: M
authors.initials: M
authors.lastname: Munari
mesh_terms: D000206:Actuarial Analysis; D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000401:mortality / Q000503:physiopathology; D011379:Prognosis; D015996:Survival Rate; D016277:Ventricular Function, Left / Q000502:physiology