Coronary vasospasm associated with uncontrolled carcinoid tumour.
We report on a 74-year-old carcinoid patient who, following acute myocardial infarction (MI) and percutaneous transluminal coronary angioplasty, suffered recurrent episodes of chest pain and ST-segment elevation on ECG. This was accompanied by elevation of urinary 5-hydroxy-indole acetic acid. A review of the patient's file revealed that during the 3 weeks prior to the MI, she had been treated inadvertently with a fivefold lower dosage of octreotide. Following the correction of octreotide dosage, episodes of chest pain resolved immediately. We therefore suggest that this patient suffered from recurrent coronary vasospasm due to uncontrolled carcinoid tumour.
Muszkat
M
M
Division of Internal Medicine, Department of Cardiology, Hadassah University Hospital, Jerusalem, Israel.
Shalit
M
M
Lotan
C
C
Ben-Yehuda
A
A
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage*; D002276:Carcinoid Tumor / Q000097:blood / Q000150:complications* / Q000188:drug therapy* / Q000556:secondary; D003329:Coronary Vasospasm / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000097:blood; D009203:Myocardial Infarction / Q000209:etiology / Q000628:therapy; D009382:Neoplasms, Unknown Primary / Q000150:complications / Q000188:drug therapy; D015282:Octreotide / Q000008:administration & dosage*
D018931:Antineoplastic Agents, Hormonal; D006897:Hydroxyindoleacetic Acid; D015282:Octreotide