title: [Squamous cell carcinoma antigen for monitoring patients with head neoplasm].
abstract: The authors present results of evaluation of squamous cell carcinoma antigen (SCC) in 73 persons (35 patients with head carcinoma and 38 healthy persons as control group). We analysed a concentration of SCC in preliminary study and in monitoring, depending on clinical advances of tumour, mass of primary tumour and metastases to lymph nodes. We observed high sensitivity (SE) (63%), high specificity (SP) (97.4%) and predictive values: positive PV(+)--95.6%, negative PV(-)--74% of SCC in preliminary study. These values changed to SE--83.3%, SP--92.3%, PV(+) 90.9%, PV(-)--85.7% in monitoring. Our results indicate that evaluation of SCC have high value in monitoring patients with head carcinoma.
authors.affiliation: Kliniki Otolaryngologicznej Centralnego Szpitala Klinicznego Wojskowej Akademii Medycznej w Warszawie.
authors.forename: G
authors.initials: G
authors.lastname: Adamiak
authors.forename: A
authors.initials: A
authors.lastname: Ligeziński
authors.forename: D
authors.initials: D
authors.lastname: Jurkiewicz
authors.forename: M
authors.initials: M
authors.lastname: Hermanowski
authors.forename: M
authors.initials: M
authors.lastname: Konieczna
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000951:Antigens, Neoplasm / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000032:analysis*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000556:secondary; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D015843:Serpins
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D015843:Serpins; C051072:squamous cell carcinoma-related antigen