title: Life-threatening acute systemic lupus erythematosus: survival after multiple extracorporeal modalities: a place for the multipotential extracorporeal service.
abstract: Diffuse alveolar hemorrhage secondary to systemic lupus erythematosus (SLE) may cause life-threatening respiratory failure and may be associated with multiple organ failure. Extensive support may be necessary to sustain life while systemic therapy becomes effective. We report here a patient with profound respiratory failure secondary to SLE associated with multiorgan failure, who was supported with veno-arterial extracorporeal lung assist (ECLA), veno-venous ECLA, and multiple continuous renal replacement therapies during plasmapheresis. The full spectrum of extracorporeal life support and treatment modalities was performed seamlessly by a single service within the critical care department.
authors.affiliation: Critical Care Medicine, R Adams Cowley Shock Trauma Center, University of Maryland Medicine, Baltimore 21201, USA.
authors.forename: M
authors.initials: M
authors.lastname: Tandon
authors.forename: H N
authors.initials: HN
authors.lastname: Reynolds
authors.forename: U
authors.initials: U
authors.lastname: Borg
authors.forename: N M
authors.initials: NM
authors.lastname: Habashi
authors.forename: C
authors.initials: C
authors.lastname: Cottingham
mesh_terms: D000208:Acute Disease; D000328:Adult; D005260:Female; D017583:Hemodiafiltration; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000628:therapy*; D010106:Oxygenators; D010951:Plasma Exchange