Sympathetic block significantly improves reperfusion in skeletal muscle following prolonged use of tourniquet.
The effects of guanethidine sympathetic nerve blocks on reperfusion of skeletal muscle was studied in rats. After 3 hours of ischaemia reperfusion was significantly better in animals that had received guanethidine.
Povlsen
B
B
Department of Hand Surgery and Biomedical Engineering, University Hospital, Linköping, Sweden. bo@povlsen.u-net.com
Sirsjö
A
A
D000818:Animals; D001340:Autonomic Nerve Block; D006145:Guanethidine; D006614:Hindlimb; D007511:Ischemia / Q000503:physiopathology; D017078:Laser-Doppler Flowmetry; D008297:Male; D018482:Muscle, Skeletal / Q000098:blood supply* / Q000294:innervation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012039:Regional Blood Flow; D015424:Reperfusion; D014111:Tourniquets
D006145:Guanethidine