title: Ischemic hepatitis induced by mesenteric volvulus in a patient with chronic obstructive lung disease.
abstract: A 66-year-old man with chronic obstructive lung disease was admitted to our hospital, presenting with mesenteric volvulus and mild liver injury. A superior mesenteric angiogram revealed that the arteries supplying the small intestine were twisted in the arterial phase, while the portal vein was not visualized in the late phase. A celiac angiogram demonstrated that portal blood flow from the splenic venous return was maintained. The patient's symptoms had almost resolved the day after admission, and his serum transaminases level had gradually decreased to normal with conservative therapy. A superior mesenteric angiogram on the 13th hospital day showed a normal arteriogram and the portal vein demonstrated blood flow from the superior mesenteric vein. Liver biopsy revealed hemorrhagic necrosis around the central veins, which was compatible with ischemic hepatitis. Since the patient's O2 saturation level on admission was not low enough to have caused ischemic hepatitis by itself, we suspect that a sudden decrease in portal blood flow was the additional factor that allowed the threshold for the initiation of ischemic liver damage to be reached.
authors.affiliation: Department of Gastroenterology Kyoto Prefectural Yosano-umi Hospital, Otokoyama, Yosa, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nakajima
authors.forename: H
authors.initials: H
authors.lastname: Konishi
authors.forename: Y
authors.initials: Y
authors.lastname: Sakamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Tatsumi
authors.forename: Y
authors.initials: Y
authors.lastname: Itoh
authors.forename: K
authors.initials: K
authors.lastname: Tokita
authors.forename: M
authors.initials: M
authors.lastname: Katoh
authors.forename: Y
authors.initials: Y
authors.lastname: Yamane
authors.forename: T
authors.initials: T
authors.lastname: Okanoue
authors.forename: K
authors.initials: K
authors.lastname: Kashima
authors.forename: H
authors.initials: H
authors.lastname: Amaike
authors.forename: H
authors.initials: H
authors.lastname: Sugihara
authors.forename: Y
authors.initials: Y
authors.lastname: Tsuchihashi
mesh_terms: D000368:Aged; D000792:Angiography; D001706:Biopsy; D006505:Hepatitis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007415:Intestinal Obstruction / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D007421:Intestine, Small / Q000098:blood supply; D007511:Ischemia / Q000209:etiology* / Q000473:pathology; D007813:Laparotomy; D008173:Lung Diseases, Obstructive / Q000150:complications*; D008297:Male; D017538:Mesenteric Artery, Superior / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed