RPR 130401, a nonpeptidomimetic farnesyltransferase inhibitor with in vivo activity.
Vrignaud
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P
Rhône-Poulenc Rorer S.A., Centre de recherche de Vitry-Alfortville, Vitry sur Seine, France. VRIGNAUD@RP-RORER.FR
Bissery
M C
MC
Mailliet
P
P
Lavelle
F
F
D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D051231:Farnesyltranstransferase; D007211:Indoles / Q000737:chemistry / Q000494:pharmacology*; D051379:Mice; D018716:Molecular Mimicry
D004791:Enzyme Inhibitors; D007211:Indoles; C400543:RPR 130401; D019883:Alkyl and Aryl Transferases; D051231:Farnesyltranstransferase