Multi gram synthesis of UDP-N-acetylmuramic acid.
As part of an effort to discover novel antibacterial agents, a new and efficient synthesis was established in order to provide a large amount of UDP-N-acetylmuramic acid (UDP-MurNAc).
Dini
C
C
Medicinal Chemistry Department, Hoechst Marion Roussel, Romainville, France. christophe.dini@hmrag.com
Drochon
N
N
Ferrari
P
P
Aszodi
J
J
D015394:Molecular Structure; D010453:Peptide Synthases / Q000737:chemistry; D014538:Uridine Diphosphate N-Acetylmuramic Acid / Q000138:chemical synthesis*
D014538:Uridine Diphosphate N-Acetylmuramic Acid; D010453:Peptide Synthases; C023229:UDP-N-acetylmuramoyl-alanine synthetase