Smoking cessation: nicotine replacement, gums and patches.
This is an overview of smoking cessation with a clinical approach. The different nicotine replacement products approximately double the long-term success rate with a dose-response effect, but with an equal efficacy of the different administration forms, so there is no long-term effect of a combination of two products, and they have only mild side-effects. The success rate will increase with the level of adjunctive behavioural support. Total smoking abstinence during the first week after quit-day is a very strong predictor of long-term success. Bupropion, an antidepressant drug, seems to be a promising drug in smoking cessation and is at least equally efficacious as nicotine products. All health care workers in pulmonary units have an obligation to deliver up-to-date smoking cessation services to their smoking patients.
Tønnesen
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Dept of Pulmonary Medicine, Gentofte University Hospital, Hellerup, Denmark.
D000279:Administration, Cutaneous; D000280:Administration, Inhalation; D000928:Antidepressive Agents / Q000627:therapeutic use; D016642:Bupropion / Q000627:therapeutic use; D002638:Chewing Gum; D006801:Humans; D009538:Nicotine / Q000008:administration & dosage* / Q000009:adverse effects; D016540:Smoking Cessation
D000928:Antidepressive Agents; D002638:Chewing Gum; D016642:Bupropion; D009538:Nicotine