[Evaluation of noradrenaline and atrial natriuretic hormone concentration in blood serum of pharmacologically untreated patients with chronic heart failure].
Heart failure is a condition of increased neurohormonal stimulation the level of which is affected by both the rate of clinical advancement of the disease and by the manner of its treatment. Hence the work of determining the level of the neuroendocrine activation of the plasma within the range of the adrenergic system and of the atrial natriuretic hormone in not pharmacologically treated patients with mild and moderate heart failure. Consistently investigated were the concentrations of noradrenaline and of the atrial natriuretic hormone in 9 patients (mean age 66.3 years) and the results of the determinations were compared with data of the age approximate group of healthy persons. Then shown, too, could be the concentration increase of noradrenaline and of the atrial natriuretic hormone (both comparisons p < 0.001) over the values that are found in healthy people.
Jabłecka
A
A
Zakładu Farmakologii Klinicznej, Instytutu Kardiologii Akademii Medycznej, Karola Marcinkowskiego w Poznaniu.
D000368:Aged; D009320:Atrial Natriuretic Factor / Q000097:blood*; D005260:Female; D006333:Heart Failure / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood*
D009320:Atrial Natriuretic Factor; D009638:Norepinephrine