The selective cytotoxicity of gamma-linolenic acid (GLA) is associated with increased oxidative stress.
Vartak
S
S
Department of Radiology, University of Iowa, Iowa City 52242, USA.
Robbins
M E
ME
Spector
A A
AA
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001253:Astrocytes / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D001254:Astrocytoma / Q000188:drug therapy / Q000378:metabolism / Q000532:radiotherapy; D002470:Cell Survival / Q000187:drug effects / Q000528:radiation effects; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology; D015237:Dinoprost / Q000031:analogs & derivatives / Q000378:metabolism; D028441:F2-Isoprostanes; D005227:Fatty Acids / Q000494:pharmacology; D005910:Glioma / Q000188:drug therapy / Q000378:metabolism / Q000532:radiotherapy; D007052:Ibuprofen / Q000494:pharmacology; D016859:Lipoxygenase Inhibitors / Q000494:pharmacology; D018384:Oxidative Stress / Q000187:drug effects*; D011836:Radiation Tolerance / Q000187:drug effects; D051381:Rats; D014407:Tumor Cells, Cultured; D017965:gamma-Linolenic Acid / Q000494:pharmacology*
D000970:Antineoplastic Agents; D016861:Cyclooxygenase Inhibitors; D028441:F2-Isoprostanes; D005227:Fatty Acids; D016859:Lipoxygenase Inhibitors; C075750:8-epi-prostaglandin F2alpha; D017965:gamma-Linolenic Acid; D015237:Dinoprost; D007052:Ibuprofen