Canine genetics comes of age.
The dog, as human's favored companion, is unique among animal species in providing new insights into human genetic disease. In this review, we will discuss both the breed and the population structure of dogs and why that makes canines amenable to genetic studies. We will review the current state of the map and discuss the particular disease states in which canines stand to make the greatest contribution to medical genetics.
Ostrander
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EA
Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N., D4-100, Seattle, WA 98109-1024, USA. eostrand@fhcrc.org
Galibert
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F
Patterson
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DF
D000818:Animals; D002874:Chromosome Mapping; D016208:Databases, Factual; D004195:Disease Models, Animal; D004283:Dog Diseases / Q000235:genetics; D004285:Dogs / Q000235:genetics*; D030342:Genetic Diseases, Inborn / Q000235:genetics / Q000662:veterinary; D008040:Genetic Linkage; D005819:Genetic Markers; D016678:Genome; D006801:Humans; D007178:Inbreeding; D018895:Microsatellite Repeats; D010375:Pedigree; D013045:Species Specificity
D005819:Genetic Markers