title: Failure of elimination of paternal mitochondrial DNA in abnormal embryos.
abstract: Paternal mitochondrial DNA is normally eliminated from mammalian embryos. We have shown the presence of paternal mtDNA at the blastocyst stage in some abnormal human embryos.
authors.forename: J
authors.initials: J
authors.lastname: St John
authors.forename: D
authors.initials: D
authors.lastname: Sakkas
authors.forename: K
authors.initials: K
authors.lastname: Dimitriadi
authors.forename: A
authors.initials: A
authors.lastname: Barnes
authors.forename: V
authors.initials: V
authors.lastname: Maclin
authors.forename: J
authors.initials: J
authors.lastname: Ramey
authors.forename: C
authors.initials: C
authors.lastname: Barratt
authors.forename: C
authors.initials: C
authors.lastname: De Jonge
mesh_terms: D001755:Blastocyst; D004272:DNA, Mitochondrial / Q000235:genetics; D004622:Embryo, Mammalian; D005220:Fathers; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D020554:Sperm Injections, Intracytoplasmic
chemical_list: D004272:DNA, Mitochondrial