[Iodine status and the used of iodized antiseptics in the mother-newborn pair].
Iodine status was evaluated by assessment of urinary iodine excretion in 221 mothers and their 223 newborns. During the first month after childbirth, 59.3 per cent of the mothers and 26.5 per cent of the newborns received applications of iodized antiseptic containing Polyvidone-iodine. 50.2 per cent of the newborns and 24.9 per cent of the mothers had a urinary iodine of more than 20 micrograms/dl (iodine excess). For the mothers and the newborns who had received applications of iodized antiseptic, 38.2 per cent and 74.6 per cent had an iodine excess, respectively. This iodine excess is directly related to use of iodized antiseptic. Such high iodine levels may contribute to the risk of thyroid disorders, and particularly to transient congenital hypothyroidism at a critical age for normal development of the nervous system.
Zahidi
A
A
Laboratoire de chimie thérapeutique, Faculté de Médecine et de Pharmacie de Rabat, Maroc.
Draoui
M
M
Mestassi
M
M
D000293:Adolescent; D000328:Adult; D000891:Anti-Infective Agents, Local / Q000009:adverse effects / Q000493:pharmacokinetics*; D003409:Congenital Hypothyroidism; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced / Q000453:epidemiology; D007231:Infant, Newborn / Q000652:urine*; D007455:Iodine / Q000009:adverse effects / Q000493:pharmacokinetics / Q000652:urine*; D008297:Male; D049590:Postpartum Period / Q000652:urine*; D011206:Povidone-Iodine / Q000009:adverse effects / Q000493:pharmacokinetics*; D011247:Pregnancy; D013959:Thyroid Diseases / Q000139:chemically induced / Q000453:epidemiology; D013963:Thyroid Hormones / Q000096:biosynthesis
D000891:Anti-Infective Agents, Local; D013963:Thyroid Hormones; D011206:Povidone-Iodine; D007455:Iodine