Fibrillary glomerulonephritis and pulmonary haemorrhage in a Woolly monkey (Lagothrix lagotricha).
Fibrillar deposits, distinct from amyloid deposits, were demonstrated by electron microscopy in the glomeruli and lung of an Amazonian Woolly monkey (Lagothrix lagotricha) which had died with extensive pulmonary haemorrhage. The renal lesions were typical of fibrillary glomerulonephritis in man, and IgG deposition was also demonstrated in the kidney. The association of renal and pulmonary lesions has been reported previously in man, but this is the first report of fibrillary glomerulonephritis, and a pulmonary-renal syndrome, in non-human animals.
Brown
P J
PJ
Comparative Pathology Laboratory, University of Bristol Veterinary School, Langford, North Somerset, BS40 5DU, UK.
MacIver
A G
AG
Harrison
R F
RF
Day
M J
MJ
Skuse
A M
AM
Munnings
N P
NP
D008841:Actin Cytoskeleton / Q000648:ultrastructure; D000818:Animals; D002427:Cebidae; D017809:Fatal Outcome; D005920:Glomerular Mesangium / Q000473:pathology / Q000648:ultrastructure; D005921:Glomerulonephritis / Q000150:complications* / Q000473:pathology; D006470:Hemorrhage / Q000150:complications* / Q000473:pathology; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000150:complications* / Q000473:pathology; D008854:Microscopy, Electron