title: [A study on the relationship between serum anticardiolipin antibody and embryo implantation in an in vitro fertilization and embryo transfer program].
abstract: OBJECTIVE
  To study the role of serum anticardiolipin antibody in embryo implantation in an in-vitro fertilization and embryo transfer program.
  
  
  METHODS
  150 in vitro fertilization and embryo transfer (IVF-ET) treatment cycles from Nov. 1994 to May, 1996 were studied. Serum anticardiolipin antibody was measured by enzyme-linked immunosorbent assay (ELISA), and the clinical pregnancy outcome observed.
  
  
  RESULTS
  Lower pregnancy rate 9.5% was found in 21 cycles of anticardiolipin antibody seropositive women compared with 26.3% in 129 cycles of anticardiolipin antibody seronegative women (P < 0.05). Patients with biochemical pregnancy and no pregnancy had seropositive anticardiolipin antibody in 20.0% and 16.2% compared with 5.6% in the patients with clinical pregnancy (P < 0.05).
  
  
  CONCLUSIONS
  Failure of embryo implantation is associated with many factors. Our study demonstrated the serum anticardiolipin antibody in patients may play a part in embryo implantation and very early postimplantation loss.
authors.affiliation: First Hospital of Shanxi Medical University, Taiyuan.
authors.forename: X
authors.initials: X
authors.lastname: Tian
authors.forename: L
authors.initials: L
authors.lastname: Zhang
authors.forename: C
authors.initials: C
authors.lastname: Yang
mesh_terms: D017153:Antibodies, Anticardiolipin / Q000097:blood*; D004624:Embryo Transfer; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D011247:Pregnancy
chemical_list: D017153:Antibodies, Anticardiolipin