Biology of chromosome 6.
The major histocompatibility (HLA) complex on the short arm of human chromosome 6 has attracted many scientists over the last three decades. It is the purpose of this brief review to point out that the remaining large regions of chromosome 6 contain genes involved in several interesting biological phenomena as well. Focus will be particularly on genes affecting behavioural features and sensory perception. The likely involvement of HLA and closely linked olfactory receptor loci in mate selection and their possible role in favouring heterozygosity among the offspring will also be discussed.
Ziegler
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Institut fuer Experimentelle Onkologie und Transplantationsmedizin, Virchow-Klinikum, Humboldt-Universitaet zu Berlin, Germany. aziegler@ukrv.de
D000818:Animals; D002874:Chromosome Mapping; D002896:Chromosomes, Human, Pair 6 / Q000235:genetics*; D005824:Genetics, Behavioral; D006801:Humans; D008285:Major Histocompatibility Complex / Q000235:genetics; D012677:Sensation / Q000235:genetics*; D012725:Sexual Behavior / Q000502:physiology; D012903:Smell / Q000235:genetics; D014785:Vision, Ocular / Q000235:genetics