Amnesic confabulatory syndrome after focal basal forebrain damage.
A 73-year-old woman developed amnesic confabulatory syndrome after a right focal basal forebrain hemorrhage. The confabulation, despite persistent antegrade amnesia, gradually subsided with improvement of the frontal executive function. The lesion appeared to disrupt connections of the medial and lateral limbic circuits important for memory. Simultaneous dysfunctioning of the two circuits involving the medial temporal and frontal lobes may be necessary for the development of this syndrome.
Hashimoto
R
R
Department of Neurology, Jichi Medical School, Minamikawachi, Tochigi, Japan.
Tanaka
Y
Y
Nakano
I
I
D000368:Aged; D000647:Amnesia / Q000000981:diagnostic imaging / Q000473:pathology* / Q000523:psychology; D001930:Brain Injuries / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009483:Neuropsychological Tests; D016548:Prosencephalon / Q000000981:diagnostic imaging / Q000473:pathology*; D013577:Syndrome; D015899:Tomography, Emission-Computed, Single-Photon