title: D-dimer after delivery in uncomplicated pregnancies.
abstract: D-dimer is now widely used as a coagulation marker. During pregnancy the D-dimer level increases until term even in uncomplicated pregnancies. The aim of the study was to establish the D-dimer immediately after delivery in uncomplicated pregnancies. A rapid immunoturbidimetric assay for D-dimer determination was employed in 100 consecutive deliveries. D-dimer level increased significantly in all women after delivery (increase from 1 to more than 10 times over the normal range).
  
  
  CONCLUSIONS
  An increase in fibrinolysis is associated with pregnancy and delivery, and D-dimer level must be interpreted only in association with other clinical, laboratory and instrumental methods when pathological conditions (e.g. pulmonary embolism, deep vein thrombosis or disseminated coagulation) are suspected.
authors.affiliation: Division of Obstetrics and Gynecology, City Hospital, Guastalla, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Ghirardini
authors.forename: M
authors.initials: M
authors.lastname: Battioni
authors.forename: C
authors.initials: C
authors.lastname: Bertellini
authors.forename: R
authors.initials: R
authors.lastname: Colombini
authors.forename: R
authors.initials: R
authors.lastname: Colla
authors.forename: G
authors.initials: G
authors.lastname: Rossi
mesh_terms: D002585:Cesarean Section; D036861:Delivery, Obstetric; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D049590:Postpartum Period / Q000502:physiology*; D011247:Pregnancy; D012016:Reference Values
chemical_list: D005338:Fibrin Fibrinogen Degradation Products