title: Surgical treatment of active infective aortic valve endocarditis with associated periannular abscess--11 year results.
abstract: OBJECTIVE
  The aim of the study was to evaluate the long-term results of allograft and prosthetic valve replacement in the treatment of infective aortic valve endocarditis with periannular abscess.
  
  
  METHODS
  Between March 1988 and March 1996, 65 patients underwent surgery for active aortic valve endocarditis and paravalvular abscess. The indications for surgery were congestive heart failure, systemic emboli and atrioventricular block III. The pre-operative evaluation was performed with transoesophageal echocardiography. Aortic valve replacement was performed with allografts in 47 cases, with mechanical valves in 15, and bioprosthetic valves in three cases. All patients with total ventricular-aortic dehiscence and prosthetic valve endocarditis were treated with allografts.
  
  
  RESULTS
  The 30-day mortality rate was 23.5% in the prosthetic group, when compared with 8.5% in the patients treated with allografts. The rate of recurrent valve infections during the 11-year follow-up period was 27.1% in the prosthetic group and 3.2% in the allograft group. The actuarial 11-year survival rate was 82.1% in the allograft group and 64.7% in the prosthetic group.
  
  
  CONCLUSIONS
  Aortic allografts are an effective treatment for infective aortic valve endocarditis with associated periannular abscess. The operative mortality and recurrent infection rates are lower than in the prosthetic group, resulting in a significantly higher survival rate. Diagnosis and surgical management of these cases should be based on pre-operative transoesophageal echocardiography.
authors.affiliation: Department of Cardiothoracic and Vascular Surgery, German Heart Institute, Berlin, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Knosalla
authors.forename: Y
authors.initials: Y
authors.lastname: Weng
authors.forename: A C
authors.initials: AC
authors.lastname: Yankah
authors.forename: H
authors.initials: H
authors.lastname: Siniawski
authors.forename: J
authors.initials: J
authors.lastname: Hofmeister
authors.forename: R
authors.initials: R
authors.lastname: Hammerschmidt
authors.forename: M
authors.initials: M
authors.lastname: Loebe
authors.forename: R
authors.initials: R
authors.lastname: Hetzer
mesh_terms: D000038:Abscess / Q000150:complications / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D001021:Aortic Valve; D018572:Disease-Free Survival; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000150:complications / Q000601:surgery*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006349:Heart Valve Diseases / Q000150:complications / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation / Q000401:mortality*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D014184:Transplantation, Homologous