title: Brain fluorine-18 fluorodeoxyglucose imaging with dual-head coincidence gamma camera: comparison with dedicated ring-detector positron emission tomography.
abstract: OBJECTIVE
  Dual-head coincidence gamma camera (DHC) imaging has been proposed as an alternative to dedicated ring-detector positron emission tomography (dr-PET) for clinical fluorodeoxyglucose (FDG) studies. The purpose of this investigation was to assess the quality of DHC images in FDG studies of the human brain.
  
  
  METHODS
  Seven healthy volunteers and 12 patients with various cerebral disorders underwent consecutive brain dr-PET and DHC with FDG. All sets of images were compared semiquantitatively using regions of interest.
  
  
  RESULTS
  Cortical count ratios to the cerebellum on DHC and dr-PET images did not differ significantly among the volunteers, except in the superior frontal cortex and thalamus. In all studies including those of cerebral disorders, the mean cortical-to-cerebellar ratios of DHC and dr-PET images correlated closely.
  
  
  CONCLUSIONS
  FDG imaging with DHC delineated the metabolic distribution of glucose in the brain as well as dr-PET did, except in the superior frontal cortex and thalamus. Therefore, DHC may be a dedicated cost-effective means of detecting metabolic abnormalities in the brain.
authors.affiliation: Department of Radiology, National Cardiovascular Center, Suita, Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Fukuchi
authors.forename: K
authors.initials: K
authors.lastname: Hayashida
authors.forename: H
authors.initials: H
authors.lastname: Moriwaki
authors.forename: K
authors.initials: K
authors.lastname: Fukushima
authors.forename: N
authors.initials: N
authors.lastname: Kume
authors.forename: T
authors.initials: T
authors.lastname: Katafuchi
authors.forename: M
authors.initials: M
authors.lastname: Sago
authors.forename: M
authors.initials: M
authors.lastname: Takamiya
authors.forename: Y
authors.initials: Y
authors.lastname: Ishida
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001927:Brain Diseases / Q000000981:diagnostic imaging*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18