title: Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans.
authors.affiliation: Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas 75390-9046, USA. mbrow1@mednet.swmed.edu
authors.forename: M S
authors.initials: MS
authors.lastname: Brown
authors.forename: J
authors.initials: J
authors.lastname: Ye
authors.forename: R B
authors.initials: RB
authors.lastname: Rawson
authors.forename: J L
authors.initials: JL
authors.lastname: Goldstein
mesh_terms: D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D000818:Animals; D001419:Bacteria / Q000201:enzymology; D022762:CCAAT-Enhancer-Binding Proteins; D004268:DNA-Binding Proteins / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism*; D004722:Endoribonucleases; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism*; D009687:Nuclear Proteins / Q000378:metabolism; D017510:Protein Folding; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D051780:Sterol Regulatory Element Binding Protein 1; D014157:Transcription Factors
chemical_list: D016564:Amyloid beta-Protein Precursor; D022762:CCAAT-Enhancer-Binding Proteins; D004268:DNA-Binding Proteins; D008565:Membrane Proteins; D009687:Nuclear Proteins; C497387:SREBF1 protein, human; D051780:Sterol Regulatory Element Binding Protein 1; D014157:Transcription Factors; C403982:ERN2 protein, human; D017346:Protein Serine-Threonine Kinases; D004722:Endoribonucleases; D010450:Endopeptidases