title: [Parkinson's disease and dementia].
abstract: Neuropsychological tests were carried out in 30 patients with Parkinson's disease and 26 healthy controls. The results showed that the average scores of HRB(A)-RC test were above the limited scores, 45.45%-86.36% cases being over the limited scores (P < 0.01), except speech sound perception test. Damage degrees (DQ) from the least to the most serious were 63.64%. WAIS-RC test and WMS test showed that the average scores of IQ and MQ in patients were lower than those in the normal. The difference of IQ, MQ scores between patients and controls was very significant (P < 0.01). The damaged cases of IQ, MQ from the least to the most serious were 20% and 60%, respectively. This indicated that the patients with Parkinson's disease were obviously damaged in intelligence and memory. In this article, there were 6 cases (20%) fitted the diagnostic standard of dementia, among them, 4 were subcortical dementia and 2 cases were complex dementia. We found that the differences between the course and IQ, MQ were very significant (P < 0.05), but not between the course and DQ. It is implied that in the very early stage, the patients could appear abnormal in neuropsychology, and the intelligence and memory may be damaged more seriously in longer course. The result suggests that the early diagnosis and prompt intervention is important to prevent the occurrence and advance of dementia.
authors.affiliation: Department of Neurology, Xiangya Hospital, Hunan Medical University, Changsha.
authors.forename: L
authors.initials: L
authors.lastname: Jin
authors.forename: W
authors.initials: W
authors.lastname: Zhang
authors.forename: H
authors.initials: H
authors.lastname: Ye
mesh_terms: D000368:Aged; D003704:Dementia / Q000150:complications* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology