The intact retroviral Env glycoprotein of human foamy virus is a trimer.
Electron microscopy of negatively stained human foamy virus particles provides direct evidence for the trimeric nature of intact Env surface glycoproteins. Three-dimensional image reconstruction reveals that the Env trimer is a tapering spike 14 nm in length. The spikes were often arranged in hexagonal rings which shared adjacent Env trimers.
Wilk
T
T
Structural Biology Programme, European Molecular Biology Laboratory, Heidelberg, Germany.
de Haas
F
F
Wagner
A
A
Rutten
T
T
Fuller
S
S
Flügel
R M
RM
Löchelt
M
M
D015686:Gene Products, env / Q000737:chemistry* / Q000648:ultrastructure; D006023:Glycoproteins / Q000737:chemistry / Q000648:ultrastructure; D006801:Humans; D011487:Protein Conformation; D012191:Retroviridae Proteins / Q000737:chemistry* / Q000648:ultrastructure; D016092:Spumavirus / Q000648:ultrastructure*
D015686:Gene Products, env; D006023:Glycoproteins; D012191:Retroviridae Proteins