title: Reversible adult respiratory distress in primary antiphospholipid syndrome.
abstract: Antiphospholipid antibody syndrome (APS) is a disorder caused by circulating antibodies reacting with biological membranes and characterized by recurrent thrombosis, chronic thrombocytopenia and miscarriages. It has been reported to occur either as a primary syndrome or secondary to systemic autoimmune disorders. We describe a case of primary APS in a young patient, in whom the clinical course was particularly severe and complicated by a respiratory distress syndrome. The patient was resistant to a number of treatments, and eventually responded to intravenous high dose corticosteroids.
authors.affiliation: Division of Hematology OFederico IIO University, Naples, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Camera
authors.forename: S
authors.initials: S
authors.lastname: Rocco
authors.forename: D
authors.initials: D
authors.lastname: De Lucia
authors.forename: C
authors.initials: C
authors.lastname: Silvia
authors.forename: A
authors.initials: A
authors.lastname: Lucania
authors.forename: G
authors.initials: G
authors.lastname: Servillo
authors.forename: G
authors.initials: G
authors.lastname: Valentini
authors.forename: B
authors.initials: B
authors.lastname: Rotoli
mesh_terms: D000293:Adolescent; D016736:Antiphospholipid Syndrome; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D012127:Respiratory Distress Syndrome, Newborn / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone