title: [Influence of cardiopulmonary bypass time on gastric intramucosal Pco2 and pH].
abstract: To determine the influence of cardiopulmonary bypass time on gastric intramucosal Pco2 and pH (pHi), 16 patients undergoing cardiopulmonary bypass (CPB) were divided into two groups according to the CPB time-- group A (n = 8) within 100 minutes and group B (n = 8) beyond 100 minutes. The gastric intramucosal Pco2 increased and the pHi decreased significantly (P< 0.01) at the end CPB compared with before operation, before bypass and 30 minutes after intermission of CPB in all patients. Between group B and A, there were significant differences in the gastric intramucosal Pco2 and in the pHi at the end of CPB. The patients of group A had no severe complications. In group B, three patients developed life-threatening complications, one of them died. The results indicate that the longer the CPB time, the greater the degree of gastric mucosal acidosis. It predicts the patients may develop life-threatening complication after cardiac operations.
authors.affiliation: Department of Anesthesiology, Xiangya Hospital, Hunan Medical University, Changsha.
authors.forename: Y
authors.initials: Y
authors.lastname: Liu
authors.forename: Q
authors.initials: Q
authors.lastname: Guo
authors.forename: H
authors.initials: H
authors.lastname: Cai
mesh_terms: D000293:Adolescent; D000328:Adult; D002245:Carbon Dioxide / Q000378:metabolism; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D002648:Child; D005260:Female; D005753:Gastric Mucosa / Q000098:blood supply / Q000378:metabolism*; D006344:Heart Septal Defects, Atrial / Q000601:surgery; D006345:Heart Septal Defects, Ventricular / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007432:Intraoperative Period; D008297:Male; D008943:Mitral Valve / Q000601:surgery; D010313:Partial Pressure; D011379:Prognosis; D013997:Time Factors
chemical_list: D002245:Carbon Dioxide