A comparison of calcaneus ultrasound and dual X-ray absorptiometry in healthy North American youths and young adults.
Quantitative ultrasound is the newest noninvasive method to be accepted for assessing bone mineral in adults. Heel ultrasound measurements correlate with bone density measurements by dual X-ray absorptiometry (DXA) and predict fracture risk in adults. Far less is known about the value of calcaneus ultrasound (CUS) in children. We determine spine, femoral neck, and whole-body bone mineral by DXA and heel bone mass by CUS in 125 youths (69 females, 56 males) ages 9-25 yr. CUS and DXA measurements of bone mass increased with age and pubertal development during adolescence in a parallel fashion. Among females, Tanner stage was a stronger predictor than age for all CUS and DXA measurements, and among males, pubertal stage was a stronger predictor for spine bone mineral apparent density (BMAD) and femoral bone mineral density (BMD). CUS measurements correlated moderately well with DXA measurements of the spine, femoral neck, and whole-body BMD and spine BMAD (r = 0.23-0.58, p < 0. 008). CUS warrants further study as a tool for assessing bone mineral acquisition in children.
Lum
C K
CK
Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA. clum@chmc.org
Wang
M C
MC
Moore
E
E
Wilson
D M
DM
Marcus
R
R
Bachrach
L K
LK
D015502:Absorptiometry, Photon; D000293:Adolescent; D000328:Adult; D000375:Aging; D015519:Bone Density; D002111:Calcaneus / Q000000981:diagnostic imaging*; D002648:Child; D005260:Female; D005272:Femur Neck / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D011627:Puberty; D012016:Reference Values; D013131:Spine / Q000000981:diagnostic imaging; D014463:Ultrasonography