title: A prospective study of acute-onset steroid acne associated with administration of intravenous corticosteroids.
abstract: Steroid acne (SA) may occur after the administration of topical or systemic corticosteroids. Because of several consultations of spinal injury patients with a very abrupt onset of a uniform papular eruption (i.e. days) initially misdiagnosed as a drug reaction or sepsis, we followed hospitalized patients who received intravenous corticosteroids (IVC) for the development of acute-onset SA in order to determine its incidence. Fifty-one consecutive subjects receiving IVC were followed for the duration of their hospital stay and examined for the development of acneiform lesions. Acute-onset SA occurred in 1 subject (2%). Acute spinal cord injury may represent a high-risk clinical setting for acute-onset SA.
authors.affiliation: Department of Dermatology, San Francisco General Hospital, University of California, San Francisco, School of Medicine, San Francisco, California, USA. fung@up.uchc.edu
authors.forename: M A
authors.initials: MA
authors.lastname: Fung
authors.forename: T G
authors.initials: TG
authors.lastname: Berger
mesh_terms: D000152:Acne Vulgaris / Q000139:chemically induced*; D000208:Acute Disease; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000009:adverse effects* / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000009:adverse effects / Q000627:therapeutic use; D003875:Drug Eruptions / Q000209:etiology; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007405:Intervertebral Disc Displacement / Q000188:drug therapy; D008297:Male; D008775:Methylprednisolone / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D011446:Prospective Studies
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone