[Synthesis of 4,5-dihydro-1,2,4-oxadiazoles from N-unsubstituted amidoximes].
4,5-Dihydro 1,2,4-oxadiazoles can be synthesized from aromatic and araliphatic amidoximes by cyclocondensation with aldehydes and ketones. Resulting heterocycles differ in substitution at C-3 and C-5 showing the scope of the simple reaction.
Lessel
J
J
Institut für Pharmazeutische Chemie, Heinrich-Heine-Universität Düsseldorf, Germany.
Herfs
G
G
D000447:Aldehydes / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D010069:Oxadiazoles / Q000138:chemical synthesis*; D010091:Oximes / Q000737:chemistry*
D000447:Aldehydes; D007659:Ketones; D010069:Oxadiazoles; D010091:Oximes