Rebound thymic hyperplasia after chemotherapy in a patient treated for pulmonary metastases.
A 38-year-old patient presented with an anterior mediastinal mass after chemotherapeutic and surgical treatment for lung metastases from a malignant histiocytoma. Because of the risk for tumour recurrence the thymic mass was resected. Thymic hyperplasia was found on pathological examination. In this case thymic hyperplasia is a rebound phenomenon aflcer chemotherapy. It appears to atrophy during the administration of chemotherapy and regrow afterwards. Surgical resection provides the definitive diagnosis and treatment.
Hendriks
J M
JM
Department of Surgery, University Hospital of Antwerp, Edegem, Belgium.
Van Schil
P E
PE
Schrijvers
D
D
Van Marck
E
E
Eyskens
E
E
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D018219:Histiocytoma, Benign Fibrous / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D008297:Male; D019042:Muscle Neoplasms / Q000188:drug therapy / Q000601:surgery*; D011013:Pneumonectomy; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000601:surgery*; D012008:Recurrence; D012086:Reoperation; D013934:Thymectomy; D013952:Thymus Hyperplasia / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed