Low frequencies of mitochondrial DNA mutations cause cardiac disease in the mouse.
Mott
J L
JL
Department of Molecular Microbiology and Immunology, St. Louis University School of Medicine, Missouri 63104, USA.
Zhang
D
D
Farrar
P L
PL
Chang
S W
SW
Zassenhaus
H P
HP
D000409:Alanine; D019943:Amino Acid Substitution; D000818:Animals; D001224:Aspartic Acid; D004272:DNA, Mitochondrial / Q000235:genetics*; D043211:Exodeoxyribonuclease V; D005090:Exodeoxyribonucleases / Q000235:genetics* / Q000378:metabolism; D006331:Heart Diseases / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D051379:Mice; D008822:Mice, Transgenic; D016297:Mutagenesis, Site-Directed; D009206:Myocardium / Q000378:metabolism / Q000473:pathology*; D018995:Myosin Heavy Chains / Q000235:genetics; D017354:Point Mutation; D011401:Promoter Regions, Genetic
D004272:DNA, Mitochondrial; D001224:Aspartic Acid; D005090:Exodeoxyribonucleases; D043211:Exodeoxyribonuclease V; D018995:Myosin Heavy Chains; D000409:Alanine