Treatment of neonatal infection caused by coxsackievirus B3.
Four male infants with early neonatal infection caused by coxsackievirus B3 (presumed in one case) exhibited severe thrombocytopenia and liver dysfunction at presentation. The three infants who were administered human normal immunoglobulin within 3 days of disease onset survived, while the fourth infant, who received the preparation 6 days after disease onset, died.
Kimura
H
H
Gunma Prefectural Institute of Public Health and Environmental Sciences, Maebashi, Japan.
Minakami
H
H
Harigaya
A
A
Takeuchi
H
H
Tachibana
A
A
Otsuki
K
K
D003384:Coxsackievirus Infections / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology / Q000821:virology; D029822:Enterovirus B, Human / Q000302:isolation & purification; D017809:Fatal Outcome; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D007231:Infant, Newborn; D008099:Liver / Q000503:physiopathology; D008297:Male; D013921:Thrombocytopenia / Q000821:virology; D013997:Time Factors; D016896:Treatment Outcome
D016756:Immunoglobulins, Intravenous