title: Clinical course of hurricane keratopathy.
abstract: OBJECTIVE
  "Hurricane keratopathy" is the name given to the whorl pattern, highlighted with fluorescein, seen in situations where corneal epithelial cell turnover is exaggerated. Although the condition is well described, follow up data on patients with this condition and its sequelae have only been reported in corneal graft patients. The aim was to study the clinical course of hurricane keratopathy in corneal graft patients and contact lens wearers, and to document any sequelae of this condition.
  
  
  METHODS
  Hurricane keratopathy, occurring in 20 eyes with corneal grafts and 16 eyes (six bilateral) wearing rigid gas permeable contact lenses, was studied and followed. The occurrence, pattern, progress, resolution, and residual effects of the whorls were noted.
  
  
  RESULTS
  Hurricane keratopathy was noted to occur in grafts as previously reported and also in contact lens wearers, which has hitherto not been reported. The whorls usually appeared within the first 3 weeks postoperatively and persisted up to 4 months. A small epithelial defect (11.1%), heaped epithelial cells (5.6%), and a nebular grade opacity (2.8%), were the only significant sequelae noted at the epicentre of the whorls. Resolution occurred from the periphery towards the centre of the cornea.
  
  
  CONCLUSIONS
  The whorl pattern is sustained as long as the stimulus for increased cell turnover is maintained. Once this stimulus is eliminated, the pattern tends to resolve spontaneously.
authors.affiliation: Department of Ophthalmology, University of Nottingham, UK.
authors.forename: H S
authors.initials: HS
authors.lastname: Dua
authors.forename: J A
authors.initials: JA
authors.lastname: Gomes
mesh_terms: D000368:Aged; D003261:Contact Lenses / Q000009:adverse effects*; D003315:Cornea / Q000473:pathology*; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology; D016039:Corneal Transplantation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000473:pathology*