[Changes in the lipid profile and thyroid function in adult patients with hypopituitarism after substitutive treatment with growth hormone].
BACKGROUND
Adult growth hormone (GH) deficiency is associated with changes in serum lipid levels that can modify after GH substitution.


METHODS
We studied 18 patients with GH deficiency treated with GH for 18 or 24 months.


RESULTS
A decrease of total cholesterol, LDL with an increase in HDL without triglycerides changes was observed. T4 levels decreased and T3 increased.


CONCLUSIONS
The GH substitution treatment in patients with GH deficiency improves the lipid profile and promotes the T4 to T3 conversion.
Gómez Sáez
J M
JM
Servicio de Endocrinología, Ciutat Sanitària i Universitària de Bellvitge, L'Hospitalet de Llobregat, Barcelona. iroigsag@jet.es
Gómez Arnaiz
N
N
Soler Ramón
J
J
D000328:Adult; D004311:Double-Blind Method; D005260:Female; D019382:Human Growth Hormone / Q000008:administration & dosage* / Q000172:deficiency; D006801:Humans; D007018:Hypopituitarism / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D018709:Statistics, Nonparametric; D013961:Thyroid Gland / Q000187:drug effects / Q000503:physiopathology*; D013997:Time Factors
D008055:Lipids; D019382:Human Growth Hormone