title: Carbamazepine-induced systemic lupus erythematosus presenting as cardiac tamponade.
abstract: Here we report the case of a patient who presented with acute cardiac tamponade due to drug-induced systemic lupus erythematosus (SLE). The patient had been treated for a seizure disorder with carbamazepine, a drug that has previously been demonstrated to cause SLE-like syndromes. Further serologic analysis demonstrated the likelihood of drug-induced SLE in this patient, with the rare presentation of cardiac tamponade.
authors.affiliation: Renal Electrolyte and Hypertension Division, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6144, USA. sunilv@att.net
authors.forename: S P
authors.initials: SP
authors.lastname: Verma
authors.forename: N
authors.initials: N
authors.lastname: Yunis
authors.forename: A
authors.initials: A
authors.lastname: Lekos
authors.forename: R S
authors.initials: RS
authors.lastname: Crausman
mesh_terms: D000208:Acute Disease; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D002220:Carbamazepine / Q000009:adverse effects* / Q000627:therapeutic use; D002305:Cardiac Tamponade / Q000139:chemically induced* / Q000175:diagnosis; D003937:Diagnosis, Differential; D004829:Epilepsy, Generalized / Q000188:drug therapy*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine