Tau protein function in axonal formation.
Tau protein is a predominantly neuronal microtubule-associated protein that is enriched in axons and is capable of promoting microtubule assembly and stabilization. In the present article we review some of the key experiments directed to obtain insights about tau protein function in developing neurons. Aspects related to whether or not tau has essential, unique, or complementary functions during axonal formation are discussed.
Paglini
G
G
Instituto Investigacion Medica Mercedes y Martin Ferreyra (INIMEC-CONICET), Cordoba, Argentina.
Peris
L
L
Mascotti
F
F
Quiroga
S
S
Caceres
A
A
D000818:Animals; D001369:Axons / Q000502:physiology*; D006801:Humans; D008870:Microtubules / Q000502:physiology / Q000648:ultrastructure; D009474:Neurons / Q000502:physiology / Q000648:ultrastructure; D016875:tau Proteins / Q000502:physiology*
D016875:tau Proteins