Diurnal preference, sleep habits, circadian sleep propensity and melatonin rhythm in healthy human subjects.
After 24-h sleep deprivation, 33 healthy young subjects entered the 10/20 min ultra-short sleep-wake schedule for 26 h. Melatonin rhythm was hourly assessed simultaneously. Results indicated that morning preference was significantly correlated with habitual sleep onset (r=-0.41, P=0.04), habitual sleep offset (r=-0.52, P=0.002), melatonin peak time (r=-0.36, P=0.04), and sleep propensity onset time (r=-0.36, P=0.04). The intervals between habitual sleep mid-point and melatonin peak time and between habitual sleep mid-point and sleep propensity onset time were significantly longer in morning-preference subjects than in evening-preference subjects (P<0.05). These findings suggest that the variance of diurnal preference may be related to differences in phase relations between habitual sleep timing and the circadian pacemaker.
Liu
X
X
Department of Psychophysiology, National Institute of Mental Health, NCNP, 1-7-3 Kohnodai, Ichikawa, Japan.
Uchiyama
M
M
Shibui
K
K
Kim
K
K
Kudo
Y
Y
Tagaya
H
H
Suzuki
H
H
Okawa
M
M
D000328:Adult; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008550:Melatonin / Q000097:blood* / Q000378:metabolism; D009043:Motor Activity; D012044:Regression Analysis; D012890:Sleep / Q000502:physiology*; D012892:Sleep Deprivation; D014851:Wakefulness
D008550:Melatonin