title: Mental disturbances during isolation in bone marrow transplant patients with leukemia.
abstract: The mental status of 39 leukemia patients, who received bone marrow transplants (BMT), was studied during the period of isolation. Mental disorders (diagnosed according to DSM-IV criteria) occurred in 16 patients (41%) during the observation period. The most frequent diagnoses were adjustment disorders, with anxiety and/or depression. Logistic regression analysis suggested higher Tension-Anxiety score in the Profile of Mood States (POMS) prior to isolation (P = 0.011), donation of the bone marrow from unrelated subjects (P = 0.026) and in female patients (P = 0.033). The results are preliminary, but indicate a high frequency of mental disturbances and highlight the importance of psychiatric intervention in BMT patients. Bone Marrow Transplantation (2000) 25, 315-318.
authors.affiliation: Department of Psychiatry, Tokyo Metropolitan Komagome General Hospital, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Sasaki
authors.forename: R
authors.initials: R
authors.lastname: Akaho
authors.forename: H
authors.initials: H
authors.lastname: Sakamaki
authors.forename: H
authors.initials: H
authors.lastname: Akiyama
authors.forename: M
authors.initials: M
authors.lastname: Yoshino
authors.forename: K
authors.initials: K
authors.lastname: Hagiya
authors.forename: M
authors.initials: M
authors.lastname: Atsumi
mesh_terms: D000293:Adolescent; D000328:Adult; D001007:Anxiety; D044466:Asian People; D016026:Bone Marrow Transplantation / Q000009:adverse effects / Q000523:psychology*; D005260:Female; D006801:Humans; D007564:Japan; D007938:Leukemia / Q000523:psychology* / Q000628:therapy; D008297:Male; D001523:Mental Disorders / Q000208:ethnology / Q000209:etiology*; D008875:Middle Aged; D019964:Mood Disorders / Q000150:complications / Q000209:etiology; D010356:Patient Isolation / Q000523:psychology*; D012044:Regression Analysis; D012737:Sex Factors; D014184:Transplantation, Homologous / Q000009:adverse effects / Q000523:psychology