[The prevalence of Chlamydia trachomatis and Ureaplasma urealyticum cervical infection in infertility women and the observation of therapeutic efficacy].
OBJECTIVE
To study the prevalence of Chlamydia trachomatis (CT) and Ureaplasma urealyticum (Uu) cervical infection in infertility women, and therapeutic effectiveness of tetracycline and qianglimycin.


METHODS
CT in cervical swab specimen was detected by cell culture, polymerase chain reaction(PCR) and immunofluorescent assay(IFA), Uu in cervical swab specimen was detected by culture, in a group of 145 infertility women, before and after treatment, and 45 women at productive age who attended obstetric and gynecologic clinic.


RESULTS
The positive rate of CT by cell culture, PCR, IFA(shell) and IFA(direct smear) was 62.7%, 66.8%, 64.8% and 36.5%, respectively, which was obviously higher than that of the control (P < 0.01). The positive rate of Uu was 33.1%, that of CT and Uu co-infection was 18.6%. Both were obviously higher than those of the control (P < 0.01).


CONCLUSIONS
This study indicates that the prevalence of CT and Uu cervical infection in infertility women is high. CT and Uu cervical infection is closely related to female infertility. The therapeutic effectiveness of tetracycline and qianglimycin is not ideal.
Luo
M
M
Department of Microbiology, Hunan Medical University, Changsha.
Zhang
L
L
Xiao
Y
Y
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002681:China / Q000453:epidemiology; D002690:Chlamydia Infections / Q000188:drug therapy* / Q000453:epidemiology; D002692:Chlamydia trachomatis; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000382:microbiology*; D015995:Prevalence; D013752:Tetracycline / Q000627:therapeutic use; D016869:Ureaplasma Infections / Q000188:drug therapy* / Q000453:epidemiology; D016990:Ureaplasma urealyticum; D002575:Uterine Cervicitis / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D013752:Tetracycline