Chromophore Alignment in a Chiral Host Provides a Sensitive Test for the Orientation - Intensity Rule of Induced Circular Dichroism.
Different inclusion modes can be realized for a bicyclic azoalkane in beta-cyclodextrin (see picture). Variations in the alignment of the azo chromophore relative to the host can be detected through NMR spectroscopy and induced circular dichroism. The latter technique produces a positive signal for the lateral conformer and a negative, significantly weaker peak for the frontal one. This is in keeping with the orientation-intensity rule.
Zhang
X
Departement Chemie der Universität Klingelbergstrasse 80, 4056 Basel (Switzerland).
Nau
WM