title: [Investigation of C1R gene frequencies in three Han populations in China].
abstract: To reveal the C1R polymorphism in Chinese, three Han populations in Guangzhou (101 samples), Jilin (105 samples) and Chengdu (111 samples) were investigated with a technique using PAGIF followed by immunoblotting. The results showed in Chengdu the C1R * 1 = 0.5676, C1R * 2 = 0.3424 and C1R * 5 = 0.0856, in Guangzhou C1R * 1 = 0.5248, C1R * 2 = 0.2663 and C1R * 5 = 0.1089, and in Jilin C1R * 1 = 0.5381, C1R * 2 = 0.2619 and C1R * 5 = 0.1714. Three rare genes C1R * 6, C1R * 7 and C1R * 8 were found in the investigation. These indicate that the frequency of C1R * 2 is elevated from north to south which may imply a geographic cline in this locus. The cumulated heterogeneity of C1R in Han population is 61.5% which means that this polymorphic system is useful in anthropolgy as well as in forensic science.
authors.forename: Z
authors.initials: Z
authors.lastname: Ji
authors.forename: Q
authors.initials: Q
authors.lastname: Gou
authors.forename: J
authors.initials: J
authors.lastname: Wu
authors.forename: Y
authors.initials: Y
authors.lastname: Hou
mesh_terms: D000483:Alleles; D044466:Asian People; D002681:China; D015923:Complement C1r / Q000235:genetics*; D005787:Gene Frequency; D005843:Geography; D006801:Humans; D011110:Polymorphism, Genetic
chemical_list: D015923:Complement C1r