title: Effectiveness of casein hydrolysate feedings in infants with colic.
abstract: This study found that two casein hydrolysate formulas varying in composition were equally effective in managing colicky symptoms associated with protein sensitivity. Both hydrolysate formulas were associated with a significant, comparable reduction in crying duration and intensity from baseline in 15 of 22 infants with complete data. Subsequent challenge data suggest that the population studied were infants experiencing colicky symptoms due to protein sensitivity. A greater proportion of infants showed a positive reaction (> or = 1.5 h of crying/d) to the protein challenges than the placebo challenge, and crying was rated as more intense during whey and milk protein challenges.
authors.affiliation: Department of Paediatrics, University Hospital, Lund, Sweden.
authors.forename: I
authors.initials: I
authors.lastname: Jakobsson
authors.forename: L
authors.initials: L
authors.lastname: Lothe
authors.forename: D
authors.initials: D
authors.lastname: Ley
authors.forename: M W
authors.initials: MW
authors.lastname: Borschel
mesh_terms: D002364:Caseins / Q000008:administration & dosage*; D003085:Colic / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D003448:Crying; D003963:Diaper Rash / Q000209:etiology; D005243:Feces; D006801:Humans; D007223:Infant; D018730:Infant Behavior; D007225:Infant Food; D007231:Infant, Newborn; D016269:Milk Hypersensitivity / Q000150:complications* / Q000175:diagnosis; D008894:Milk Proteins / Q000009:adverse effects; D011492:Protein Hydrolysates / Q000008:administration & dosage*; D012893:Sleep Wake Disorders / Q000209:etiology; D014839:Vomiting / Q000209:etiology
chemical_list: D002364:Caseins; D008894:Milk Proteins; D011492:Protein Hydrolysates; C026375:trypticase-soy broth