title: An outbreak of calicivirus associated with consumption of frozen raspberries.
abstract: In April 1988, an outbreak of gastroenteritis occurred among employees in a large company in Helsinki, Finland. A retrospective cohort study, using a self-administered questionnaire, was carried out to ascertain the cause and extent of the outbreak. To meet the case definition, employees had to have had diarrhoea and/or vomiting since 2 April, 1998. A subanalysis was made in the biggest office, consisting of 360 employees, of whom 204 (57%) completed the questionnaire. Of these 108 (53%) met the case definition. Employees who had eaten raspberry dressing were more likely to meet the case definition than those who had not (Attack Rate (AR) 65% versus AR 18% Relative Risk, (RR) 3.7, 95%, Confidence Intervals (CI) 2.0-6.7). Four stool specimens obtained from affected kitchen staff who had all eaten the raspberry dressing and who had all become ill simultaneously with the employees were positive by polymerase chain reaction (PCR) for calicivirus. The data suggest that the primary source of the outbreak was imported frozen raspberries contaminated by calicivirus.
authors.affiliation: Helsinki City Center of the Environment, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Pönkä
authors.forename: L
authors.initials: L
authors.lastname: Maunula
authors.forename: C H
authors.initials: CH
authors.lastname: von Bonsdorff
authors.forename: O
authors.initials: O
authors.lastname: Lyytikäinen
mesh_terms: D000328:Adult; D002139:Caliciviridae / Q000472:pathogenicity*; D017250:Caliciviridae Infections / Q000453:epidemiology*; D015331:Cohort Studies; D004196:Disease Outbreaks; D005260:Female; D005387:Finland / Q000453:epidemiology; D005506:Food Contamination; D005628:Frozen Foods / Q000821:virology; D005638:Fruit / Q000821:virology; D005759:Gastroenteritis / Q000209:etiology / Q000821:virology; D006801:Humans; D008297:Male; D012189:Retrospective Studies