title: Bone marrow necrosis in a cat infected with feline leukemia virus.
abstract: A one-year old castrated male cat was admitted to the hospital with vomiting and diarrhea. Laboratory examination revealed pancytopenia and positive for FeLV antigen. A bone marrow examination indicated necrosis of the nucleated cells. Based on these findings, the cat was diagnosed as bone marrow necrosis. Pancytopenia was effectively treated with corticosteroids. Re-examination of the bone marrow confirmed a recovery of normal hematopoietic cells with a infiltration of many macrophages. It is strongly suspected that the bone marrow necrosis in this case could be associated with a bone marrow suppression due to FeLV infection.
authors.affiliation: Sanyo Animal Medical Center, Akaiwva, Okayama, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Shimoda
authors.forename: N
authors.initials: N
authors.lastname: Shiranaga
authors.forename: T
authors.initials: T
authors.lastname: Mashita
authors.forename: A
authors.initials: A
authors.lastname: Hasegawa
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000097:blood; D001706:Biopsy / Q000662:veterinary; D001853:Bone Marrow / Q000473:pathology*; D002371:Cat Diseases / Q000188:drug therapy / Q000473:pathology* / Q000821:virology; D002415:Cats; D003907:Dexamethasone / Q000627:therapeutic use; D003967:Diarrhea / Q000662:veterinary; D005938:Glucocorticoids / Q000627:therapeutic use; D006400:Hematocrit / Q000662:veterinary; D005256:Leukemia Virus, Feline / Q000187:drug effects / Q000472:pathogenicity*; D009336:Necrosis; D009504:Neutrophils / Q000473:pathology; D010198:Pancytopenia / Q000662:veterinary; D010976:Platelet Count / Q000662:veterinary; D011239:Prednisolone / Q000627:therapeutic use; D011379:Prognosis; D012192:Retroviridae Infections / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D014412:Tumor Virus Infections / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D014839:Vomiting / Q000662:veterinary
chemical_list: D000956:Antigens, Viral; D005938:Glucocorticoids; D003907:Dexamethasone; D011239:Prednisolone