[Circadian rhythm of PGE2 level in plasma and condylar cartilage of young growing rats].
This paper reports the circadian rhythm of PEG2 level in plasma and condylar cartilage of young frowing rats. The samples were measured at 0:00, 4:00, 8:00, 12:00, 16:00, and 20:00 respectively. The count of PGE2 were determined by RIA and analysed with simple Cosinor and coordination. The results revealed: (1) The levels of PGE2 in plasma and condylar cartilage of young growing rats fluctuated in strong circadian rhythm; (2) The rhythm of PGE2 in plasma between 16:00 and 24:00 was significantly different from that between 4:00 and 12:00, so for analysing PGE2 level in plasma, one should proper sampling time or adjust it to circadian rhythm; (3) The circadian rhythm of PGE2 in condylar cartilage could provide important reference for reatments in dentistry and orthopaedics.
Jiang
Z
Z
Department of Immunology, School of Basic Medical Sciences, Chengdu.
Wang
Z
Z
Lei
X
X
Yang
X
X
Chen
Y
Y
D000818:Animals; D002356:Cartilage / Q000378:metabolism; D002940:Circadian Rhythm; D015232:Dinoprostone / Q000097:blood / Q000378:metabolism*; D005260:Female; D008297:Male; D008335:Mandibular Condyle / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
D015232:Dinoprostone