[Role of bronchospasm in impairment of bronchial permeability in bronchial asthma in attack-free period].
Lung capacity (LC), functional lung capacity (FLC), FEV1, FEV1/LC%, CO25, CO50, CO75 were measured in 56 patients with bronchial asthma in attach-free period before and after inhalation of one-dose berotec and one-dose atrovent. Bronchospasm was registered in 66% of the patients. It was the only cause of bronchial obstruction in 12% of the patients and one of the causes in 54% of them. Contribution of the bronchospasm to development of bronchial obstruction was, as a rule, dominating. This contribution reached 81-100% in 60% of the patients.
Nefedov
V B
VB
Popova
L A
LA
D000280:Administration, Inhalation; D000328:Adult; D001249:Asthma / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control; D001986:Bronchial Spasm / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D016084:Bronchoconstriction / Q000187:drug effects / Q000502:physiology*; D001993:Bronchodilator Agents / Q000008:administration & dosage; D005260:Female; D005280:Fenoterol / Q000008:administration & dosage; D006801:Humans; D009241:Ipratropium / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D012129:Respiratory Function Tests
D001993:Bronchodilator Agents; D005280:Fenoterol; D009241:Ipratropium