Genomic imprinting and Beckwith-Wiedemann syndrome.
Genomic imprinting is the parental-allele-specific expression of genes. Beckwith-Wiedemann syndrome (BWS), a congenital overgrowth syndrome with increased risk of childhood tumors, is one of the well-known diseases caused by imprinted genes. The imprinted genes causing BWS are discussed in this review.
Hatada
I
I
Gene Research Center, Gunma University, Maebashi, Japan. ihatada@akagi.sb.gunma-u.ac.jp
Mukai
T
T
D001506:Beckwith-Wiedemann Syndrome / Q000235:genetics*; D002648:Child; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D050761:Cyclin-Dependent Kinase Inhibitor p57; D005260:Female; D018392:Genomic Imprinting; D006801:Humans; D008297:Male; D009154:Mutation; D009369:Neoplasms / Q000453:epidemiology / Q000235:genetics; D009687:Nuclear Proteins / Q000235:genetics
C493964:CDKN1C protein, human; D050761:Cyclin-Dependent Kinase Inhibitor p57; D009687:Nuclear Proteins