title: The use of polytetrafluoroethylene (Gore-Tex) grafts in reconstruction of the urinary bladder.
abstract: The safety and histopathologic effects of polytetrafluoroethylene (Gore-Tex) grafts in reconstruction of the urinary bladder were examined. Following partial excision of the bladder Gore-Tex was placed, and the rats were sacrificed at days 7, 14 and 30. Gore-Tex did not cause urine infection, and there was no peritonitis or sepsis in any of the rats. Inflammation around the Gore-Tex diminished after four weeks. Some mononuclear cells and exudate were observed on the inner surface of the Gore-Tex. There was no inflammation or fibrosis in the mucosa and muscular layers of the remaining bladder. In this study the Gore-Tex graft was found to be an infection resistant, urine impermeable material, with no adverse effects on the urinary bladder. Gore-Tex is suggested as a safe material for the reconstruction of the urinary bladder.
authors.affiliation: Department of Urology, Abant Izzet Baysal University, Düzce Medical School, Bolu, Turkey.
authors.forename: F M
authors.initials: FM
authors.lastname: Senel
authors.forename: R Y
authors.initials: RY
authors.lastname: Akman
authors.forename: A Y
authors.initials: AY
authors.lastname: Arikan
authors.forename: M
authors.initials: M
authors.lastname: Gürdal
authors.forename: C
authors.initials: C
authors.lastname: Can
mesh_terms: D000818:Animals; D006965:Hyperplasia; D008297:Male; D011138:Polytetrafluoroethylene; D051381:Rats; D017208:Rats, Wistar; D019651:Plastic Surgery Procedures; D001743:Urinary Bladder / Q000473:pathology / Q000601:surgery*
chemical_list: D011138:Polytetrafluoroethylene