[The effect of a cryoextract of the chorion on the cellular reaction of an inflammatory focus].
On the model of carrageenan-induced acute aseptic peritonitis in rats it is shown that in inflammation on the background of administration of chorion's cryoextract a marked inhibition of neutrophilic reaction and stimulation of macrophagic fibroblastic one, and earlier ending of inflammation is observed, i.e. cryoextract of chorion has an expressive anti-inflammatory action which is mainly realized by inhibition of pathologic reactions and stimulation of protective ones in the blood.
Klymenko
M O
MO
Kharkov State Medical University, Ministry of Public Health of Ukraine.
Subota
N P
NP
Pit'ko
V A
VA
Tatarko
S V
SV
D000208:Acute Disease; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002351:Carrageenan; D002823:Chorion / Q000737:chemistry*; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D008297:Male; D010538:Peritonitis / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014020:Tissue Extracts / Q000627:therapeutic use*
D000893:Anti-Inflammatory Agents; D014020:Tissue Extracts; D002351:Carrageenan