[Adaptation to irradiation in vivo].
The data about the increasing of radioresistance of cells and organism after the acute, chronic and prolonged irradiation in vivo were presented. The possible mechanisms of adaptation to irradiation connected with selection, stimulation of proliferative activity, forming of protecting system (protected proteins, antioxidant enzymes e.a.), activation of DNA repair and cAMP-, and Ca(2+)-dependent phosphorylation systems were observed. The conclusion about complex mechanism of radiation adaptation was drawn.
Koterov
A N
AN
State Research Center of Russia-Institute of Biophysics, Moscow.
Nikol'skiĭ
A V
AV
D000220:Adaptation, Biological; D000818:Animals; D006801:Humans; D011832:Radiation Injuries; D011836:Radiation Tolerance