Predictive values of the ICT Tuberculosis test for the routine diagnosis of tuberculosis in Madagascar.
The rapid commercialised ICT Tuberculosis test has been tested in Madagascar for the diagnosis of smear-positive pulmonary (SM+) and extra-pulmonary tuberculosis (EPT), using microscopy, culture and histopathology as reference tests. Specificity was 83.3% and sensitivity 68.2% for SM+ patients and 65.2% for EPT patients. With a prevalence of 22.2% for SM+ patients and 52.4% for confirmed EPT among consulting patients in the National Reference Laboratory, the ICT Tuberculosis assay was not sufficiently predictive for application in the tuberculosis control programme.
Rasolofo
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V
Institut Pasteur de Madagascar, Tuberculosis National Reference Laboratory, Antananarivo. vrasolof@pasteur.mg
Rasolonavalona
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T
Ramarokoto
H
H
Chanteau
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S
D003906:Developing Countries; D005260:Female; D006801:Humans; D008270:Madagascar; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D012680:Sensitivity and Specificity; D012698:Serologic Tests / Q000379:methods; D014374:Tuberculin Test; D014376:Tuberculosis / Q000175:diagnosis*