title: What controls the rates of interprotein electron-transfer reactions.
abstract: Rates of electron-transfer (ET) reactions are dependent on driving force, reorganizational energy, distance, and the nature of the medium which the electron must traverse. In kinetically complex biological systems, non-ET reactions may be required to activate the system for ET and may also influence the observed rates. Studies of ET from tryptophan tryptophylquinone to copper to heme in the methylamine dehydrogenase-amicyanin-cytochrome c-551i ET complex, as well as studies of other physiologic redox protein complexes, are used to illustrate the combination of factors which control rates of interprotein ET reactions.
authors.affiliation: Department of Biochemistry, The University of Mississippi Medical Center, Jackson, Mississippi 39216-4505, USA. vdavidson@biochem.umsmed.edu
authors.forename: V L
authors.initials: VL
authors.lastname: Davidson
mesh_terms: D004579:Electron Transport; D004735:Energy Transfer; D007700:Kinetics; D011506:Proteins / Q000737:chemistry; D013816:Thermodynamics
chemical_list: D011506:Proteins