[The systems analysis of protective-adaptive reactions in immunopathology].
In the systems approach to the study into the closed control circuits (CCC) of the self-regulation apparatus two combinations have been established of functioning (variable) quantities. A decrease in somatotropin and hypoglycemia and correspondingly an increment in somatostatin and insulin determine the redundant measure of defence against injury, the converse values in the analyzed parameters determine autoimmune processes. Alternation of the above parameters accompanied by exacerbation-remission and remission-exacerbation is directed to securing an adaptive final effect--recovery. Apparent structural-and-functional disturbances in certain regulators of any CCC are accompanied by persisting pathological conditions listed for each heading.
Reznik
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IP
D000222:Adaptation, Physiological / Q000276:immunology*; D015551:Autoimmunity / Q000276:immunology; D006706:Homeostasis / Q000276:immunology; D006801:Humans; D007154:Immune System Diseases / Q000276:immunology*; D007108:Immune Tolerance / Q000276:immunology; D013597:Systems Analysis