[Hereditary predisposition in the formation of allergic diseases in children].
Results are submitted of investigations designed to gain insights into the part hereditary aggravation (HA) in respect of atopy plays in the origination of allergic disorders (AD) in early childhood and to study objective markers of atopy and bronchial asthma (BA). Close correlation (P < 0.01) was established between HA and AD development, increase in the total IgE level and skin scarification tests. In BA, manifest bronchial hyperreactivity is accompanied by rise in total IgE, which observation can be related to their associated inheritance.
Akopian
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AZ
D000293:Adolescent; D000704:Analysis of Variance; D001249:Asthma / Q000175:diagnosis / Q000209:etiology / Q000235:genetics / Q000503:physiopathology; D016535:Bronchial Hyperreactivity / Q000175:diagnosis / Q000209:etiology / Q000235:genetics; D002648:Child; D005260:Female; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000209:etiology / Q000235:genetics*; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D012307:Risk Factors; D012882:Skin Tests / Q000379:methods / Q000706:statistics & numerical data
D007073:Immunoglobulin E