Cellular effects of a new farnesyltransferase inhibitor, RPR-115135, in a human isogenic colon cancer cell line model system HCT-116.
Russo
P
P
Laboratory of Molecular Pharmacology, National Institutes of Health, Bethesda, Maryland 20892, USA. patrusso@hp380.ist.unige.it
Ottoboni
C
C
Falugi
C
C
Reinhold
W
W
Riou
J F
JF
Parodi
S
S
O'Connor
P M
PM
D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors*; D003110:Colonic Neoplasms / Q000473:pathology*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D051231:Farnesyltranstransferase; D006801:Humans; D008954:Models, Biological; D014407:Tumor Cells, Cultured
D004791:Enzyme Inhibitors; D019883:Alkyl and Aryl Transferases; D051231:Farnesyltranstransferase