title: Aero-allergen sensitisation patterns amongst atopic Zimbabwean children.
abstract: OBJECTIVE
  To characterize children presenting with atopic conditions using the RAST test.
  
  
  METHODS
  Retrospective descriptive study.
  
  
  METHODS
  General paediatric clinic in the private sector.
  
  
  METHODS
  84 children aged below 12 years, who had the RAST test, who presented to a general paediatric clinic between 1993 and 1998 with atopic conditions for care.
  
  
  RESULTS
  The median age for all children in the study was 52 months. Forty eight were male and 36 female. Eczema (33.9%) was the most frequent clinical diagnosis especially in those less than 24 months of age, followed by asthma (25.5%), allergic conjunctivitis (24.0%) and allergic rhinitis (15.6%). Total IgE was not statistically significantly associated with clinical diagnosis(p = 0.889), age of the child (p = 0.102), gender (p = 0.687) or absolute eosinophil count (p = 0.318). The commonest allergens identified were dust mite (Dermatophygoides pteronissinus and D. farinae) and Bermuda grass. While antibody reaction to weeds, particularly plantain, were also common, these reactions were mostly mild to moderate. Allergy to cats and moulds was rare.
  
  
  CONCLUSIONS
  In the absence of routine testing for specific allergens avoidance of dust mite and Bermuda grass seem important strategies in the management of difficult children with atopy. There is need for a prospective study to shed more light on the allergens that cause these common atopic conditions in our environment.
authors.affiliation: Department of Paediatrics and Child Health, University of Zimbabwe Medical School, Avondale, Harare.
authors.forename: R A
authors.initials: RA
authors.lastname: Kambarami
authors.forename: F
authors.initials: F
authors.lastname: Marechera
authors.forename: E N
authors.initials: EN
authors.lastname: Sibanda
authors.forename: M E
authors.initials: ME
authors.lastname: Chitiyo
mesh_terms: D000485:Allergens / Q000009:adverse effects*; D000818:Animals; D001249:Asthma / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D003233:Conjunctivitis, Allergic / Q000209:etiology*; D004391:Dust / Q000009:adverse effects*; D004485:Eczema / Q000209:etiology*; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000097:blood / Q000175:diagnosis* / Q000209:etiology* / Q000276:immunology; D008297:Male; D008925:Mites; D006109:Poaceae / Q000009:adverse effects*; D011852:Radioallergosorbent Test; D012189:Retrospective Studies; D012221:Rhinitis, Allergic, Perennial / Q000209:etiology*; D015030:Zimbabwe
chemical_list: D000485:Allergens; D004391:Dust