title: [Behavioral-teratological effects of caffeine on mice].
abstract: Pregnant ICR mice were exposed to caffeine at levels of 0, 4, 20 and 100 mg/kg during pregnancy. The behavioral-teratological tests indicated that the retardation of development, the obstruction of early reflexes and sensation and decline of learning ability existed in the offsprings of 20 and 100 mg/kg groups. The number of the dead fetus increased in the group of 100 mg/kg coffeine treated mice. No morphological changes were found.
authors.affiliation: Hengyang Hygiene and Antiepidemic Station, China.
authors.forename: W
authors.initials: W
authors.lastname: Yin
authors.forename: H
authors.initials: H
authors.lastname: Li
authors.forename: L
authors.initials: L
authors.lastname: Peng
mesh_terms: D000818:Animals; D002110:Caffeine / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D005314:Embryonic and Fetal Development; D005260:Female; D008431:Maternal-Fetal Exchange; D018782:Maze Learning; D051379:Mice; D008813:Mice, Inbred ICR; D019957:Motor Skills Disorders / Q000139:chemically induced*; D011247:Pregnancy
chemical_list: D002110:Caffeine