The manifold of vitamin B6 dependent enzymes.
Pyridoxal-5'-phosphate (vitamin B6) binding enzymes form a large superfamily that contains at least five different folds. The availability of an increasing number of known three-dimensional structures for members of this superfamily has allowed a detailed structural classification. Most progress has been made with the fold type I or aspartate aminotransferase family.
Schneider
G
G
Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, S-171 77, Sweden. gunter@alfa.mbb.ki.se
Käck
H
H
Lindqvist
Y
Y
D000411:Alanine Racemase / Q000737:chemistry / Q000378:metabolism; D000410:Alanine Transaminase / Q000737:chemistry / Q000378:metabolism; D000818:Animals; D001219:Aspartate Aminotransferases / Q000737:chemistry / Q000378:metabolism; D051263:D-Alanine Transaminase; D004798:Enzymes / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D006005:Phosphorylases / Q000737:chemistry / Q000378:metabolism; D017510:Protein Folding; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D011736:Pyridoxine / Q000378:metabolism*; D014367:Tryptophan Synthase / Q000737:chemistry / Q000378:metabolism
D004798:Enzymes; D006005:Phosphorylases; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D051263:D-Alanine Transaminase; D014367:Tryptophan Synthase; D000411:Alanine Racemase; D011736:Pyridoxine