[Antioxidative effect of constituents of herba Epimedii (ESPS)].
Herba Epimedii is a traditional Yang invigorating Chinese herb widely used in clinic. The experimental results have shown that ESPS obviously increases superoxide dismutase(SOD) activity of red cells and liver in aged mice and rats, and increases glutathione peroxidase(GSH-Px) activity of red cells in aged mice. On the other hand, ESPS obviously helps to reduce the content of serum and liver lipoperoxide(LPO) in aged mice and rats, as well as the content of lipofuscin(LF) in cardiac muscle of aged mice. The results suggest that being helpful in increasing SOD and GSH-Px activities and inhibiting the formation of LPO and LF, ESPS may be a good antiageing agent.
Zeng
N
N
Chengdu University of TCM.
Meng
X
X
Zhang
Y
Y
Lai
X
X
Zheng
J
J
Chen
L
L
Ren
C
C
D000375:Aging / Q000187:drug effects*; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005979:Glutathione Peroxidase / Q000378:metabolism*; D008054:Lipid Peroxides / Q000378:metabolism; D008062:Lipofuscin / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D019684:Magnoliopsida; D008297:Male; D051379:Mice; D051381:Rats; D017207:Rats, Sprague-Dawley; D013482:Superoxide Dismutase / Q000378:metabolism*
D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D008054:Lipid Peroxides; D008062:Lipofuscin; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase