[Vascular reactivity and thrombus formation during postischemic reperfusion].
Reactivity, thrombogeneity, and thromboresistance of the rat mesentery microvessels were studied in postischemic reperfusion of the intestine, the brain, an extremity. Irrespective of ischemia localisation, an augmentation of the microvessels reactivity and reduction of their thromboresistance, were found. The microvessels thrombogeneity was depended on the ischemia localisation: an augmentation of the thrombogenity occurred in arterioles whereas it was reduced in venules following the brain and intestine reperfusion. A possible mechanism of the phenomenon may involve a deficiency of the nitric oxide synthesis.
Vlasov
T D
TD
I. P. Pavlov State Medical University, St. Petersburg, Russia.
D000818:Animals; D001160:Arterioles; D001921:Brain / Q000098:blood supply; D006614:Hindlimb / Q000098:blood supply; D007421:Intestine, Small / Q000098:blood supply; D008297:Male; D008643:Mesentery / Q000098:blood supply*; D008833:Microcirculation; D051381:Rats; D015427:Reperfusion Injury / Q000150:complications / Q000503:physiopathology*; D013927:Thrombosis / Q000209:etiology / Q000503:physiopathology*; D014699:Venules