title: Clinicopathological study of recurrent uterine cervical squamous-cell carcinoma.
abstract: OBJECTIVE
  To improve prognoses of patients with recurrent uterine cervical squamous-cell carcinoma.
  
  
  METHODS
  We clinicopathologically analyzed 464 patients with uterine cervical squamous-cell carcinoma (126 positive, 338 negative pelvic lymph-node metastasis) who were treated at the Saitama Cancer Center from January 1, 1976 to December 31, 1991.
  
  
  RESULTS
  The recurrence rates of negative pelvic lymph-node metastasis patients were 14. 2% (39/274) in pT1b and 32.8% (21/64) in pT2b. But for positive lymph-node metastasis patients the rates were 39.0% (23/59) in pT1b and 58.2% (39/67) in pT2b. The interval to recurrence was shorter in positive pelvic lymph-node patients than in negative patients. The 5-year survival rates after relapse of negative lymph-node patients with intrapelvic, extrapelvic, and both-sites recurrence were 53, 12, and 40%, respectively. But among distant recurrent sites, lung metastasis in negative lymph-node patients and lymphatic tract metastasis brought relatively fair prognoses.
  
  
  CONCLUSIONS
  Regular long-term checks are necessary and active retreatments are recommended for patients with local recurrences, lung metastasis, or lymphatic vessel metastatic lesions.
authors.affiliation: Division of Gynecology, Saitama Cancer Center, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Shiromizu
authors.forename: T
authors.initials: T
authors.lastname: Kasamatsu
authors.forename: T
authors.initials: T
authors.lastname: Honma
authors.forename: K
authors.initials: K
authors.lastname: Matsumoto
authors.forename: T
authors.initials: T
authors.lastname: Shirai
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
mesh_terms: D001859:Bone Neoplasms / Q000401:mortality / Q000556:secondary; D002294:Carcinoma, Squamous Cell / Q000401:mortality* / Q000556:secondary; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local / Q000401:mortality* / Q000473:pathology; D010534:Peritoneal Neoplasms / Q000401:mortality / Q000556:secondary; D011379:Prognosis; D012878:Skin Neoplasms / Q000401:mortality / Q000556:secondary; D002583:Uterine Cervical Neoplasms / Q000401:mortality* / Q000473:pathology