title: Outcome in recipients of dual kidney transplants: an analysis of the dual registry patients.
abstract: BACKGROUND
  A novel but controversial method to increase the utilization of aged donor kidneys is the transplantation of both kidneys as a dual transplant. Initial single-center reports demonstrated outcomes similar to single kidneys from younger donors. In this report, we compare outcome in recipients of kidneys from donors > or =54 years of age who received a single kidney transplant reported to the United Network for Organ Sharing Scientific Registry versus a dual kidney transplant reported to the Dual Kidney Registry.
  
  
  METHODS
  A retrospective analysis was performed, comparing four donor and nine recipient and outcome variables between recipients of a single versus a dual transplant between March 1993 and March 1999.
  
  
  RESULTS
  Dual versus single transplants from donors > or =54 years of age have a significantly decreased incidence of delayed graft function, and lower serum creatinines up to 2 years after transplant despite having kidneys from significantly older donors with poorer HLA matching.
  
  
  CONCLUSIONS
  Dual kidney transplants improve graft performance and outcome in recipients of kidneys from donors > or =54 years of age.
authors.affiliation: Department of Surgery, Stanford University, California 94305, USA.
authors.forename: A D
authors.initials: AD
authors.lastname: Lu
authors.forename: J T
authors.initials: JT
authors.lastname: Carter
authors.forename: R J
authors.initials: RJ
authors.lastname: Weinstein
authors.forename: R J
authors.initials: RJ
authors.lastname: Stratta
authors.forename: R J
authors.initials: RJ
authors.lastname: Taylor
authors.forename: V D
authors.initials: VD
authors.lastname: Bowers
authors.forename: L E
authors.initials: LE
authors.lastname: Ratner
authors.forename: K D
authors.initials: KD
authors.lastname: Chavin
authors.forename: L B
authors.initials: LB
authors.lastname: Johnson
authors.forename: P C
authors.initials: PC
authors.lastname: Kuo
authors.forename: E H
authors.initials: EH
authors.lastname: Cole
authors.forename: D C
authors.initials: DC
authors.lastname: Dafoe
authors.forename: E J
authors.initials: EJ
authors.lastname: Alfrey
mesh_terms: D000368:Aged; D006801:Humans; D016030:Kidney Transplantation / Q000379:methods / Q000502:physiology; D008875:Middle Aged; D012042:Registries; D014019:Tissue Donors; D016896:Treatment Outcome