title: The adult unoperated cleft patient: absence of maxillary teeth outside the cleft area.
abstract: OBJECTIVE
  The purpose of this study was to investigate the possible absence of teeth in the postcanine region of the upper jaw of the unoperated adult cleft patient.
  
  
  METHODS
  The study was performed on 266 dental casts of fully unoperated adult cleft patients. The patients were divided into four groups according to the type of the cleft: unilateral cleft lip and alveolus, unilateral cleft lip and palate, bilateral cleft lip and alveolus, and bilateral cleft lip and palate.
  
  
  RESULTS
  No absence of permanent teeth in the canine and postcanine area of the upper jaw could be found.
  
  
  CONCLUSIONS
  The results are in contradiction with the established hypothesis that absence of teeth outside the cleft area of the maxilla is due to an unknown congenital factor. On the contrary, the findings support the hypothesis that surgery for the closure of the hard palate in early childhood is the most important etiological factor for the absence of teeth outside the cleft area in the early operated cleft patient. The superficial position of the tooth germs (at the time of the palatal surgery), especially those of the premolars, supports this hypothesis.
authors.affiliation: University of Leiden, The Netherlands.
authors.forename: C
authors.initials: C
authors.lastname: Lekkas
authors.forename: B S
authors.initials: BS
authors.lastname: Latief
authors.forename: S P
authors.initials: SP
authors.lastname: ter Rahe
authors.forename: A M
authors.initials: AM
authors.lastname: Kuijpers-Jagtman
mesh_terms: D000293:Adolescent; D000328:Adult; D000848:Anodontia / Q000150:complications / Q000453:epidemiology*; D002971:Cleft Lip / Q000150:complications*; D002972:Cleft Palate / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008437:Maxilla; D003765:Models, Dental