[Anesthetic management of a patient with West syndrome].
A 21-year-old female with West syndrome was scheduled for resection of hordeolum. She had an episode of convulsion at three months of age, and was diagnosed as having West syndrome at one year of age. She had epileptic seizures twice a week in spite of administration of phenytoin, clonazepam and sodium valproate. These drugs had been administered till the morning of the surgery. After premedication with atropine 0.25 mg, anesthesia was induced with propofol (12-->10-->8 mg.kg-1.h-1). The tracheal intubation was performed with vecuronium 0.1 mg.kg-1 and anesthesia was maintained with continuous infusion of propofol 6-8 mg.kg-1.h-1 and local infiltration with 1.0% lidocaine 5 ml. We administered phenytoin to prevent epileptic seizures during the surgery. No epileptic seizures occurred perioperatively. We conclude that propofol may be useful for a patient with West syndrome, and we should be careful not to lower the threshold for convulsion during the perioperative period.
Yamaguchi
S
S
First Department of Anesthesiology, Dokkyo University School of Medicine, Tochigi.
Mishio
M
M
Okuda
Y
Y
Kitajima
T
T
D000328:Adult; D000771:Anesthesia, Intravenous; D018686:Anesthetics, Intravenous; D000927:Anticonvulsants / Q000008:administration & dosage; D004827:Epilepsy / Q000517:prevention & control; D005260:Female; D006726:Hordeolum / Q000150:complications / Q000601:surgery; D006801:Humans; D007431:Intraoperative Complications / Q000517:prevention & control; D019990:Perioperative Care; D010672:Phenytoin / Q000008:administration & dosage; D015742:Propofol; D013036:Spasms, Infantile / Q000150:complications
D018686:Anesthetics, Intravenous; D000927:Anticonvulsants; D010672:Phenytoin; D015742:Propofol