[Mechanisms for the therapeutic effect of herpes polyvaccines in chronic ophthalmic herpes and genital herpes].
Commercial inactivated culture polyvaccine against herpes simplex viruses (types 1 and 2) developed at D. I. Ivanovsky Institute of Virology promoted cessation of viremia. During the first vaccination viremia coincided with appearance of a focal allergic test on the retina, which is proposed for the diagnosis of herpetic involvement of the posterior compartment of the eye. T-cellular immunity normalized after a course of vaccination. Experimental immunization of rats and vaccination of patients with chronic ophthalmic and genital herpes demonstrated the therapeutic activity of inactivated herpetic polyvaccine in suppositoria.
Barinskiĭ
I F
IF
Karpovich
L G
LG
Gubanova
E I
EI
Belkina
I V
IV
Semenova
T B
TB
Lazarenko
A A
AA
Davydova
A A
AA
Samoĭlenko
I I
II
Kasparov
A A
AA
D000818:Animals; D006558:Herpes Genitalis / Q000097:blood / Q000276:immunology / Q000628:therapy*; D006801:Humans; D016849:Keratitis, Herpetic / Q000097:blood / Q000276:immunology / Q000628:therapy*; D051381:Rats; D013601:T-Lymphocytes / Q000276:immunology; D014765:Viral Vaccines / Q000627:therapeutic use*; D014766:Viremia
D014765:Viral Vaccines