title: A pilot investigation of the effect of tryptophan manipulation on the affective state of male chronic alcoholics.
abstract: A pilot study was conducted to investigate the hypothesis that dietary tryptophan manipulation would influence self-report affective status in alcoholic males. No significant effect of dietary manipulation was observed on the tryptophan/large neutral amino acids ratio or psychological indices of affect. The notion that dietary manipulation may be utilized in improving mood state in alcoholic males was not supported.
authors.affiliation: Hull and East Yorkshire Hospitals NHS Trust, Institute of Rehabilitation, 215 Anlaby Road, Hull HU3 2PG, UK.
authors.forename: C R
authors.initials: CR
authors.lastname: Martin
authors.forename: A B
authors.initials: AB
authors.lastname: Bonner
mesh_terms: D000328:Adult; D000339:Affect; D000437:Alcoholism / Q000097:blood / Q000178:diet therapy* / Q000523:psychology; D000704:Analysis of Variance; D004040:Dietary Carbohydrates / Q000627:therapeutic use*; D004044:Dietary Proteins / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011795:Surveys and Questionnaires; D014364:Tryptophan / Q000097:blood / Q000627:therapeutic use*
chemical_list: D004040:Dietary Carbohydrates; D004044:Dietary Proteins; D014364:Tryptophan