Electrophysiological correlates of human intrasaccadic processing.
Visual discrimination performance is thought to be suppressed during saccades in order to contribute to space constancy. However, under certain experimental conditions, visual inhibition may not take place, suggesting a more complex underlying mechanism. We tested the discrimination ability of 20 healthy subjects during visually guided horizontal saccades and recorded simultaneously the evoked brain activity from 30 channels over occipital, parietal, and temporal areas. During the execution of saccadic eye movements, visual stimuli were presented for 30 ms. In order to prevent retinal afterimages, stimuli were followed by a visual mask. In a control condition, the same stimuli were presented with stationary eyes. Electro-oculogram (EOG) and electroencephalogram (EEG) signals were recorded continuously together with information about the stimuli and the subject's response. Evoked potentials were computed offline, and component latency, field strength (global field power), and topography were compared between conditions. During saccades, subjects showed only slightly reduced discrimination performance which remained very high above the chance level; thus, there was no evidence for strong saccadic suppression with the supra-threshold stimuli employed. However, the cortical activation patterns exhibited large alteration when a physically identical stimulus was presented during the eye movement: around 130 ms latency, field strength was significantly smaller than when stationary targets were processed, and scalp topography was also different. These effects on evoked field distributions may be attributed to neural interactions of an efference copy signal (linked to the oculomotor command) with the afferent excitation following the visual stimulus.
Anagnostou
E
E
Institute of Physiology, School of Medicine, Justus-Liebig University, Giessen, Germany.
Kleiser
R
R
Skrandies
W
W
D000328:Adult; D001931:Brain Mapping; D004192:Discrimination, Psychological; D004569:Electroencephalography; D004585:Electrooculography; D005074:Evoked Potentials, Visual; D005403:Fixation, Ocular / Q000502:physiology*; D006801:Humans; D009778:Occipital Lobe / Q000502:physiology*; D010296:Parietal Lobe / Q000502:physiology*; D010775:Photic Stimulation; D012438:Saccades / Q000502:physiology*; D013702:Temporal Lobe / Q000502:physiology*; D014796:Visual Perception