title: Sedation and analgesia.
abstract: Sedation is a process of soothing. The concept of the ideal level of sedation is controversial and has changed over the last decade. A shift from deep sedation, often enhanced by muscle relaxants that completely detaches the patient from their environment, to light sedation rendering the patient sleepy but easily arousable has been widely accepted. This change in attitude has been brought about by sophisticated modes of ventilation allowing the ventilator to synchronize with the patient's own breathing pattern. In addition, the increasingly recognised adverse effects of over-sedation have contributed to the reduction in the depth of sedation.
authors.affiliation: John Farman Intensive Care Unit, Addenbrooke's Hospital, Cambridge, UK.
authors.forename: C
authors.initials: C
authors.lastname: Lerch
authors.forename: G R
authors.initials: GR
authors.lastname: Park
mesh_terms: D000698:Analgesia / Q000379:methods*; D016292:Procedural Sedation / Q000379:methods*; D003422:Critical Care / Q000379:methods*; D016638:Critical Illness; D006801:Humans; D006993:Hypnotics and Sedatives
chemical_list: D006993:Hypnotics and Sedatives