title: Psychiatric symptoms of inherited metabolic disease.
abstract: Inborn errors of metabolism often present with a variety of psychiatric symptoms. With improved diagnosis and treatment options, many patients have increased lifespans; consequently, issues of long-term quality of life are coming to the forefront. Mental health concerns are among these issues. To demonstrate the connection between the course of metabolic disease and its psychiatric manifestations, four different inborn errors of metabolism are reviewed: phenylketonuria, Wilson disease, acute intermittent porphyria, and metachromatic leukodystrophy.
authors.affiliation: Department of Psychiatry, University of California, San Diego, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Estrov
authors.forename: F
authors.initials: F
authors.lastname: Scaglia
authors.forename: O A
authors.initials: OA
authors.lastname: Bodamer
mesh_terms: D006527:Hepatolenticular Degeneration / Q000523:psychology*; D006801:Humans; D007966:Leukodystrophy, Metachromatic / Q000523:psychology*; D001523:Mental Disorders / Q000209:etiology*; D008661:Metabolism, Inborn Errors / Q000523:psychology*; D010661:Phenylketonurias / Q000523:psychology*; D017118:Porphyria, Acute Intermittent / Q000523:psychology*