title: Influence of porous coating level on proximal femoral remodeling. A postmortem analysis.
abstract: This study used femurs retrieved at autopsy to compare the extent and location of bone remodeling between four patients implanted with proximally porous coated femoral prostheses and a matched group of four patients implanted with extensively porous coated femoral prostheses. The femoral components studied were large, cementless, straight, cobalt chrome stems and were identical except for the amount of porous coating. The contralateral normal femur of each patient also was retrieved, implanted with an identical prosthesis, and used as a control for bone mineral content. Dual energy x-ray absorptiometric analysis showed marked loss of bone mineral content in both groups of patients. The extensively coated group had less bone loss on average (18.4%) than did the proximally coated group (38.6%). There was no relationship between the extent of coating and the location of bone mineral loss; specifically, proximal coating did not protect against loss of bone mineral content proximally or distally in the femur. Videodensitometric analysis of cross sections of periprosthetic bone also showed that the extensively coated group tended to have less decrease in bone density than did the proximally coated group (14.3% versus 28.4%). Although one cannot presume that all proximally fixed stem designs would produce results similar to those presented here, these findings show that decreasing the extent of porous coating alone does not necessarily reduce proximal femoral bone loss.
authors.affiliation: Anderson Orthopaedic Research Institute, Alexandria, VA 22306, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: McAuley
authors.forename: C J
authors.initials: CJ
authors.lastname: Sychterz
authors.forename: C A
authors.initials: CA
authors.lastname: Engh
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D015519:Bone Density / Q000502:physiology*; D016723:Bone Remodeling / Q000502:physiology*; D020099:Coated Materials, Biocompatible; D019544:Equipment Failure Analysis; D005260:Female; D005269:Femur / Q000473:pathology; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000473:pathology*; D011474:Prosthesis Design
chemical_list: D020099:Coated Materials, Biocompatible