[P53 protein expression in malignant germ cell tumor of ovary and its relationship with clinical course and prognosis].
To study the relationship of P53 protein expression with clinical course and prognosis in malignant germ cell tumor of ovary P53 protein expression was examined by immunohistochemical ABC methods in 82 cases of the neoplasm and 20 cases of normal ovary tissue. The results showed that no expression of P53 protein was detected in normal ovarian tissue. The total expression rate of P53 protein was 24.39% in neoplasm, and the expression was not significantly correlated with the different histological types of neoplasm. The study however found that the protein expression of p53 gene was significantly correlated with the clinical stages and prognosis of the neoplasm.
Gao
G
G
Department of Obstetrics and Gynecology, Second Affiliated Hospital, Chengdu.
Peng
Z
Z
Wang
H
H
Chen
A
A
Yao
X
X
D002822:Choriocarcinoma / Q000378:metabolism / Q000473:pathology; D018240:Endodermal Sinus Tumor / Q000378:metabolism / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D018237:Germinoma / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000378:metabolism* / Q000473:pathology; D015996:Survival Rate; D013724:Teratoma / Q000378:metabolism / Q000473:pathology; D016159:Tumor Suppressor Protein p53 / Q000096:biosynthesis*
D016159:Tumor Suppressor Protein p53