Cloning of a novel chemoattractant receptor activated by leukotriene B4 and used by human immunodeficiency virus type 1 to infect CD4-positive immune cells. A therapeutic connection to asthma?
Owman
C
C
Division of Molecular Neurobiology, Wallenberg Neuroscience Center, University of Lund, Lund, Sweden. christer.owman@mphy.lu.se
Sabirsh
A
A
Garzino-Demo
A
A
Cocchi
F
F
D000818:Animals; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy*; D015496:CD4-Positive T-Lymphocytes / Q000378:metabolism / Q000821:virology*; D002630:Chemotactic Factors / Q000378:metabolism*; D003001:Cloning, Molecular / Q000379:methods*; D015658:HIV Infections / Q000378:metabolism / Q000821:virology; D015497:HIV-1 / Q000187:drug effects / Q000378:metabolism / Q000472:pathogenicity*; D006801:Humans; D020024:Leukotriene Antagonists / Q000627:therapeutic use; D007975:Leukotriene B4 / Q000494:pharmacology*; D008024:Ligands; D051379:Mice; D008969:Molecular Sequence Data; D044042:Receptors, Formyl Peptide; D015728:Receptors, HIV / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D011971:Receptors, Immunologic / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D018000:Receptors, Peptide / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*
D018927:Anti-Asthmatic Agents; D002630:Chemotactic Factors; D020024:Leukotriene Antagonists; D008024:Ligands; D044042:Receptors, Formyl Peptide; D015728:Receptors, HIV; D011971:Receptors, Immunologic; D018000:Receptors, Peptide; D007975:Leukotriene B4