Adrenocorticosterone alterations in male, albino mice treated with Trichopus zeylanicus, Withania somnifera and Panax ginseng preparations.
The levels of corticosterone were estimated by the HPLC method in the adrenal glands of stressed (5 h constant swimming) male albino mice treated with Trichopus zeylanicus, Withania somnifera and Panax ginseng preparations and compared with non-treated stressed and normal controls. The treatments increased the corticosterone levels in all the groups. The physical endurance (increased survival time) of swimming mice also increased in all the treated groups, except in the group treated with Withania somnifera powder (500 mg/kg, p.o.).
Singh
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Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar (Mohali), Near Chandigarh - 160062, India.
Saxena
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Bhutani
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D000311:Adrenal Glands / Q000187:drug effects*; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003345:Corticosterone / Q000032:analysis*; D008297:Male; D051379:Mice; D005894:Panax; D005082:Physical Exertion / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal; D011897:Random Allocation; D013550:Swimming
D010936:Plant Extracts; D003345:Corticosterone