Patient participation in medical decision-making: a French study in adjuvant radio-chemotherapy for early breast cancer.
BACKGROUND
Shared decision-making is increasingly advocated as an ideal model. However, very few studies have tested the feasibility of giving patients the opportunity to participate in the choice of treatment.


METHODS
Women, with non-metastatic breast cancer, eligible for non-intensified adjuvant chemotherapy attending our hospital were proposed two administrations of chemotherapy and radiotherapy: a sequential and a concomitant one. Two patient-questionnaires were used to elicit motivations for their choice and their degree of comfort with the process of decision-making and one questionnaire to test physicians' ability to predict patients' choice.


RESULTS
Participation rate in the study was 75.3% (n = 64). Majority (64%) of patients chose the concomitant treatment. Multivariate analysis revealed that patients with a lower level of education, who discussed the choice with social circle, and who most feared side-effects were more likely to choose the sequential treatment. Physicians were able to predict patients' choice in 66% of cases. 89% of patients declared that they were fully satisfied with having participated in the choice of treatment and 79% supported shared decision-making.


CONCLUSIONS
Results are in favour of promoting active participation of cancer-patients in medical decision-making. The adequate degree of such participation remains however to be elicited and tested for therapeutic choices implying more difficult trade-offs between quantity and quality of life.
Protière
C
C
Institut Paoli-Calmettes, Regional Centre for Cancer Care, Marseilles, France.
Viens
P
P
Genre
D
D
Cowen
D
D
Camerlo
J
J
Gravis
G
G
Alzieu
C
C
Bertucci
F
F
Resbeut
M
M
Maraninchi
D
D
Moatti
J P
JP
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001294:Attitude to Health; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000523:psychology / Q000532:radiotherapy* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D002755:Choice Behavior; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004522:Educational Status; D005260:Female; D005602:France; D006801:Humans; D008875:Middle Aged; D008942:Mitoxantrone / Q000008:administration & dosage; D010358:Patient Participation; D010820:Physicians / Q000523:psychology; D011795:Surveys and Questionnaires
D003520:Cyclophosphamide; D008942:Mitoxantrone