Regulation of appetite in chronic renal failure.
Anorexia, nausea and vomiting in patients with severe renal failure may cause or contribute to development of protein-energy malnutrition, which is associated with increased morbidity and mortality. However, the specific mechanisms that cause appetite suppression in uremia are poorly understood. This review summarizes the general mechanisms by which appetite is regulated. Various factors are discussed that may potentially be involved in appetite suppression in chronic renal failure.
Bergström
J
J
Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Karolinska Institutet, Stockholm, Sweden. jonas.bergstrom@kfcmail.hs.sll.se
D000596:Amino Acids / Q000502:physiology; D001069:Appetite Regulation; D016207:Cytokines / Q000502:physiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology*; D018377:Neurotransmitter Agents / Q000502:physiology; D009569:Nitric Oxide / Q000502:physiology
D000596:Amino Acids; D016207:Cytokines; D018377:Neurotransmitter Agents; D009569:Nitric Oxide