title: Unusual recurrence of cervical adenosquamous carcinoma after conservative surgery.
abstract: The use of less radical procedures for the treatment of early cervical cancers is gaining interest among physicians and young patients. Some authors have described surgical procedures aimed at reducing the surgical aggressiveness but the safety of such procedures remains debated. After a polypectomy, a young patient had a diagnosis of stage Ia(2) cervical adenosquamous carcinoma in 1995. As she wished to preserve her fertility, she underwent a cone biopsy and pelvic lymphadenectomy, without evidence of tumor spread. In 1998, at the 13th week of gestation, she had a diagnosis of a pelvic mass. The mass was a recurrence of carcinoma involving the myometrium, just underneath the peritoneum. She underwent a radical hysterectomy with bilateral oophorectomy. An ovarian metastasis was also detected at pathological exam. She received chemotherapy postoperatively and remains alive without evidence of disease. The recurrence of cervical cancer is traditionally regarded as an issue concerning the cervix, the parametria, or the lymph nodes. When the uterus is preserved we must also consider the possibility of a recurrence involving the corpus. With wider acceptance of limited therapeutic approaches we must be prepared for the detection of previously unknown patterns of recurrence and the follow-up modalities must be consequently adapted.
authors.affiliation: Department of Obstetrics and Gynecology, University of Milano Bicocca, Monza, 20052, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Zanetta
authors.forename: A
authors.initials: A
authors.lastname: Gabriele
authors.forename: F
authors.initials: F
authors.lastname: Vecchione
authors.forename: F
authors.initials: F
authors.lastname: Landoni
authors.forename: G
authors.initials: G
authors.lastname: Isimbaldi
mesh_terms: D000328:Adult; D018196:Carcinoma, Adenosquamous / Q000473:pathology / Q000556:secondary* / Q000601:surgery*; D019092:Conization; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D010051:Ovarian Neoplasms / Q000556:secondary*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery*; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery