Leukocyte adhesion deficiency in a Norwegian boy.
A Norwegian boy suffering from recurrent urinary and respiratory tract infections was examined. It was found that granulocyte random migration, respiratory burst activity and the proportions of CD11/CD18 receptor positive leukocytes were reduced, consistent with a diagnosis of leukocyte adhesion deficiency. An increased proportion of Fc gammaI-receptor-bearing granulocytes did not compensate for the CR3 deficiency.
Naess
A
A
Institute of Medicine, Haukeland Hospital, University of Bergen, Norway.
Sjursen
H
H
Leegaard
J
J
D000293:Adolescent; D018845:CD11 Antigens / Q000032:analysis; D018821:CD18 Antigens / Q000032:analysis; D006801:Humans; D018370:Leukocyte-Adhesion Deficiency Syndrome / Q000276:immunology*; D008297:Male; D017452:Receptors, IgG / Q000032:analysis
D018845:CD11 Antigens; D018821:CD18 Antigens; D017452:Receptors, IgG