[The experimental study about the relations between Chinese herb-epimedium leptorrhizum stearn (CH-ELS) and endogenous cAMP in alveolar bone of orthodontic tooth in rats].
The aim of this study was, to explore the mechanism of CH-ELS promoting bone remodelling of orthodontic tooth in rats. 11 male sprague-Dawleg rats was divided into 3 groups. Group I (normal control group) Group II (applied force, no injection) Group III (applied force, injection). The experimental period was 3 days. The radioimmunoassay (RIA) method were used to investigate the effects of CH-ELS on the content of endogenous cAMP in alveolar bone of orthodontic tooth in rats. Results indicate that CH-ELS has no significant effects on endogenous cAMP in alveolar bone of orthodontic tooth, perhaps, cAMP were not involved to regulate the mechanism of CH-ELS promoting bone remodelling. To explore the mechanism of bone remodelling of orthodontic tooth is more significant in orthodontic clinic.
Peng
G
G
School of Stomatology, Beijing Medical University.
Fu
M
M
Zhang
D
D
D000539:Alveolar Process / Q000378:metabolism*; D000818:Animals; D016723:Bone Remodeling; D000242:Cyclic AMP / Q000378:metabolism*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D019684:Magnoliopsida; D008297:Male; D009971:Orthodontics, Corrective; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley
D004365:Drugs, Chinese Herbal; D000242:Cyclic AMP