[Comparative structural study of the glial blastomas of the central nervous system].
The objective of our work is to compare 2 diagnostics methods and demonstrate the similarities of the different Central Nervous System Glial Tumor Classifications. Immuno-marking techniques for gliofibrilar acid protein (GFAP), and special silver impregnations to compare the results according to the last histogenetic interpretations were used. 95 Gliomas were studied with hematoxiline-eosine and silver techniques, and in 58 randomized selected cases the technique for GFAP was also used. Both methods showed the same results in the diagnosis of Glial Tumors whose cells possess gliofibrils: Glioepitelioma (Ependymoma), Glioblastoma, Astroblastoma, and Astrocytoma. In the Oligodendrioglomas whose cells possess microtubules but not gliofibrils, the silver techniques marked these cells and their prolongations while the technique for GFAP did not. Regarding Gliomas, there are similarities by comparing the Del Río Ortega-Polak classification with those of the WHO and other authors. There are differences only in the "names" of some tumors or in their histogenetic interpretation, which are not substantial and are confined to the "Polar Espongioblastoma" and "Gliosarcoma". Therefore, we think that the recognition of the Del Río Hortega-Polak classification is justified.
Rodríguez
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3a Cátedra de Patología, Hospital Misericordia.
Cejas
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D001932:Brain Neoplasms / Q000145:classification / Q000473:pathology; D016543:Central Nervous System Neoplasms / Q000145:classification / Q000473:pathology*; D005910:Glioma / Q000145:classification / Q000473:pathology*; D006801:Humans; D016622:Silver Staining; D013120:Spinal Cord Neoplasms / Q000145:classification / Q000473:pathology