Alopecia areata-like hair loss in C3H/HeJ mice and DEBR rats can be reversed using topical diphencyprone.
This study demonstrates the ability to treat successfully alopecia areata-like hair loss in both mouse and rat models using topical immunotherapy with diphencyprone.
Shapiro
J
J
Division of Dermatology, University of British Columbia, Vancouver, Canada.
Sundberg
J P
JP
Bissonnette
R
R
McElwee
K J
KJ
McLean
D I
DI
Carroll
J M
JM
Oliver
R F
RF
Tang
L
L
Lui
H
H
D000287:Administration, Topical; D000506:Alopecia Areata / Q000188:drug therapy*; D000818:Animals; D003521:Cyclopropanes / Q000008:administration & dosage*; D051379:Mice; D051381:Rats
D003521:Cyclopropanes; C029402:diphenylcyclopropenone