title: [Distribution and features of infection with hepatitis viruses B and C during hemodialysis treatment].
abstract: The prevalence of hepatitides B and C was evaluated in 140 patients treated by hemodialysis. Almost half of patients (48%) had acute hepatitis B which completely resolved. Acute hepatitis B was detected in 6% in the course of observation. In 6% chronic hepatitis B was diagnosed, and in 24% chronic hepatitis C. A combination of hepatitides B and C was diagnosed in 2% patients. Only 12% patients were not infected with hepatitis. Genotype 1b predominated in patients with HCV infection (73%); genotypes 1a, 21, and 3a were equally incident (9%). Replication of HBV and HCV in patients with uremia under conditions of hemodialysis was detected in 83 and 86% patients, respectively. Relationship between HBV and HCV infection and the duration of hemodialysis treatment was analyzed. The percentage of non-infected patients persistently decreased, and the time course of HBV and HCV infection was different. Infection with HBV after the beginning of hemodialysis occurred sooner (16.0 +/- 4.0 months) than with HCV (30.2 +/- 4.6 months, p < 0.04). The levels of SGPT and SGOT in patients with various manifestations of HBV and HCV infection treated by hemodialysis were followed up.
authors.forename: M L
authors.initials: ML
authors.lastname: Zubkin
authors.forename: N A
authors.initials: NA
authors.lastname: Selivanov
authors.forename: V M
authors.initials: VM
authors.lastname: Stakhanova
authors.forename: V G
authors.initials: VG
authors.lastname: Novozhenov
authors.forename: E P
authors.initials: EP
authors.lastname: Sel'kova
authors.forename: T E
authors.initials: TE
authors.lastname: Kucherova
authors.forename: F S
authors.initials: FS
authors.lastname: Baranova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Kozhokar'
authors.forename: V V
authors.initials: VV
authors.lastname: Kirkhman
authors.forename: E N
authors.initials: EN
authors.lastname: Kasapova
authors.forename: I I
authors.initials: II
authors.lastname: Stenina
authors.forename: D K
authors.initials: DK
authors.lastname: L'vov
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D005838:Genotype; D016174:Hepacivirus / Q000235:genetics; D006509:Hepatitis B / Q000201:enzymology / Q000453:epidemiology* / Q000635:transmission; D006526:Hepatitis C / Q000201:enzymology / Q000453:epidemiology* / Q000635:transmission; D006801:Humans; D015995:Prevalence; D006435:Renal Dialysis / Q000009:adverse effects*
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase