The influence of a low protein diet in idiopathic hypercalciuria.
A group of 42 hypercalciuric patients (24 males and 18 females) aged 23 to 61 years (mean 45.57+/-12.27) with recurrent stone disease was studied. We applied for a period of 10 days a normocalcium, moderately low protein diet. We found statistically significant variations of azotaemia, venous pH, and vitamin D 1-25. In the 24 h urine collection we found a statistically significant decrease of nitrogen, uric acid, sodium, chloride, calcium, phosphates, oxalate, and hydroxyproline. In conclusion, the present study suggests that the restricted consumption of animal protein can produce a limited effect in urinary biochemistry. The actual efficiency of this dietary restriction on stone formation remains to be evaluated by a prospective long-term study of a larger population. Whether this has an effect on the future incidence of stone formation has to be further verified.
Liatsikos
E N
EN
Department of Urology, University of Patras, School of Medicine, Greece.
Barbalias
G A
GA
D000328:Adult; D002118:Calcium / Q000652:urine*; D018753:Diet, Protein-Restricted; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D012008:Recurrence
D002118:Calcium