[Study on the immunoregulatory effect of Baoyuantang ([symbol: see text]) in patients with chronic hepatitis B].
The T lymphocyte colong, formition (TL-CFU), the T lymphocyte subsets (CD3+, CD4+ and CD8+) and interieakin-2 membrane receptor (mIL-2R) secreted by peripheral mononuclear cells of 60 patients with chronic B hepatitis were studied. The results indicated that the activity of TL-CFU, mIL-2R and CD3+, CD4+, CD4+/CD8+ were decreased, and CD8+ was increased as compared with the normal controls. After treatment with Baoyuantang, the TL-CFU, mIL-2R, CD3+, CD4+ and CD4+/CD8+ increased and CD8+ decreased as well. It is suggested that the patients with the chronic B hepatitis with immune function defficiency, and the Baoyuartan treatment is presented immunoregulatory.
Yang
J
J
Department of Traditional Chinese Medicine, Second Affiliated Hospital, Hunan Medical University, Changsha.
Wu
H
H
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006509:Hepatitis B / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000096:biosynthesis; D016176:T-Lymphocyte Subsets / Q000187:drug effects*
D000276:Adjuvants, Immunologic; D004365:Drugs, Chinese Herbal; D015375:Receptors, Interleukin-2