title: Influence of selective breeding on the prevalence of chorioretinal dysplasia and coloboma in the rough collie in Sweden.
abstract: A total of 8204 rough collies, representing 76 per cent of all collies registered by the Swedish Kennel Club between 1989 and 1997, were examined before 10 weeks of age for collie eye anomaly (CEA). All dogs were permanently identified and examination results were registered and computerised. The policy of breeders during the study period was to select against coloboma in breeding stock, but to allow breeding of chorioretinal dysplasia (CRD) affected animals. The prevalence of CRD increased significantly from 54.2 per cent to 68.1 per cent (P < 0.001) from 1989 to 1997, while the prevalence of coloboma did not (8.3 per cent to 8.5 per cent, P = 0.4). These results are not compatible with a simple, recessive, autosomal inheritance for the entire CEA complex.
authors.affiliation: Bagarmossen Referral Animal Hospital, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Wallin-Håkanson
authors.forename: N
authors.initials: N
authors.lastname: Wallin-Håkanson
authors.forename: A
authors.initials: A
authors.lastname: Hedhammar
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D015862:Choroid Diseases / Q000235:genetics / Q000662:veterinary*; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D005260:Female; D008297:Male; D010375:Pedigree; D015995:Prevalence; D015792:Retinal Dysplasia / Q000235:genetics / Q000662:veterinary*; D013548:Sweden / Q000453:epidemiology