title: Comparison of two serotype 1 MDV isolates.
abstract: We compared the RB1B and T. King (TK) serotype 1 isolates of Marek's disease virus (MDV) in vivo. Body and organ weights, mortality, and lesions indicated that the TK inoculum established early infection more efficiently than RB1B and did greater damage to the bursa of Fabricius and thymus. Subsequent studies showed that the TK inoculum that we used contained chicken infectious anemia virus (CIAV). Therefore, pathogenicity profiles shown here should be interpreted with the presence of CIAV contamination in the TK stock in mind.
authors.affiliation: Delaware Agricultural Experiment Station, Department of Animal and Food Sciences, College of Agricultural Sciences, University of Delaware, Newark 19717-1303, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Miles
authors.forename: A S
authors.initials: AS
authors.lastname: Anderson
authors.forename: E L
authors.initials: EL
authors.lastname: Bernberg
authors.forename: J
authors.initials: J
authors.lastname: Kent
authors.forename: J K
authors.initials: JK
authors.lastname: Rosenberger
authors.forename: C R
authors.initials: CR
authors.lastname: Pope
authors.forename: R W
authors.initials: RW
authors.lastname: Morgan
mesh_terms: D000818:Animals; D001835:Body Weight; D002060:Bursa of Fabricius / Q000473:pathology; D002645:Chickens / Q000821:virology*; D008381:Herpesvirus 2, Gallid / Q000145:classification* / Q000302:isolation & purification / Q000472:pathogenicity*; D008380:Marek Disease / Q000401:mortality / Q000473:pathology / Q000821:virology*; D009929:Organ Size; D012703:Serotyping; D013154:Spleen / Q000473:pathology; D013950:Thymus Gland / Q000473:pathology