Comparison between pentazocine, pethidine and placebo in the treatment of post-anesthetic shivering.
BACKGROUND
We have compared the effects of pethidine, pentazocine and placebo in the treatment of post-anesthetic shivering.


METHODS
Forty-five patients who shivered after routine surgery were allocated randomly to receive normal saline (n=15), pentazocine 7.5 mg (n=15) or pethidine 17.5 mg (n=15).


RESULTS
After 10 min, 13 patients had stopped shivering in the pethidine group, which was significantly more than the incidence in the two other groups (placebo=2; pentazocine=4) (P<0.01). Pentazocine was not significantly different from normal saline in affecting shivering.


CONCLUSIONS
We conclude that pentazocine 7.5 mg was not effective in the treatment of post-anesthetic shivering.
Terasako
K
K
Division of Anesthesia, Kyoto Katsura Hospital, Japan.
Yamamoto
M
M
D000328:Adult; D000368:Aged; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008614:Meperidine / Q000627:therapeutic use*; D008875:Middle Aged; D010423:Pentazocine / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy*; D012768:Shivering / Q000187:drug effects*
D000701:Analgesics, Opioid; D008614:Meperidine; D010423:Pentazocine