title: Congenital hypopituitarism in a 48-year old adult. Natural course, hormonal study and MRI evidence.
abstract: A case of Congenital Hypopituitarism (CH) in an untreated 48 yr-old-man is reported. The hormonal studies demonstrated a panhypopituitarism and MR imaging revealed absence of pituitary stalk, small anterior pituitary remnant on the sella floor and ectopic neurohypophysis at the tuber cinereum. The pattern of hormonal responsiveness suggests that CH encompasses findings typical of primary anterior pituitary disease and those of hypothalamic dysfunction.
authors.affiliation: Department of Internal Medicine, University of Pisa, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Pentimone
authors.forename: S
authors.initials: S
authors.lastname: Riccioni
authors.forename: L
authors.initials: L
authors.lastname: Del Corso
mesh_terms: D003346:Corticotropin-Releasing Hormone; D007987:Gonadotropin-Releasing Hormone; D006728:Hormones / Q000097:blood; D006801:Humans; D007018:Hypopituitarism / Q000151:congenital* / Q000175:diagnosis / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010902:Pituitary Gland / Q000002:abnormalities; D013973:Thyrotropin-Releasing Hormone
chemical_list: D006728:Hormones; D007987:Gonadotropin-Releasing Hormone; D013973:Thyrotropin-Releasing Hormone; D003346:Corticotropin-Releasing Hormone