Prevention of subdural fluid collections following transcortical intraventricular and/or paraventricular procedures by using fibrin adhesive.
OBJECTIVE
Subdural fluid collections following transcortical intraventricular and/or paraventricular neurosurgical procedures for tumors are common and can be difficult to treat. The authors prospectively studied the efficacy of a fibrin adhesive (Tisseel) in closing cortical and ependymal defects following intraventricular and/or paraventricular lesion resection and in preventing the development of subdural fluid collections.


METHODS
Twenty-five patients who underwent 29 transcortical approaches for the resection of intraventricular and/or paraventricular lesions were studied. No patient developed a symptomatic subdural fluid collection and no new seizure or progression of a preexisting seizure disorder was encountered during a median follow-up time of 29 months (range 1-57 months). The incidence of preoperative hydrocephalus was 72% and four (22%) of these patients required postoperative shunt placement.


CONCLUSIONS
The use of a fibrin adhesive to seal cortical and ependymal defects after transcortical procedures appears to prevent the development of subdural fluid collections.
Al-Yamany
M
M
Brain Tumor Research Laboratories, Centre for Pediatric Neurosciences, University of Western Ontario, London, Canada.
Del Maestro
R F
RF
D000293:Adolescent; D000328:Adult; D000368:Aged; D002540:Cerebral Cortex / Q000601:surgery; D002551:Cerebral Ventricle Neoplasms / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D003399:Craniotomy; D004805:Ependyma / Q000601:surgery; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D012086:Reoperation; D013353:Subdural Effusion / Q000517:prevention & control*; D016896:Treatment Outcome
D015718:Fibrin Tissue Adhesive