Biochemical and haematological variables in Gambian children with cerebral malaria.
Biochemical and haematological measurements were made in Gambian children who satisfied the criteria for the diagnosis of cerebral malaria over a 3-year period. Biochemical and haematological values were available for 388 and 624 children, respectively. Biochemical signs of renal and hepatic dysfunction were found and these may have contributed in a cumulative way to the high mortality seen in the study children. Cerebral involvement in children with cerebral malaria is only one, though the most important, manifestation of a multi-organ disease.
Enwere
G C
GC
Royal Victoria Hospital, Banjul, The Gambia, West Africa.
Van Hensbroek
M B
MB
Jaiteh
B
B
Palmer
A
A
Onyiorah
E
E
Schneider
G
G
Weber
M W
MW
Greenwood
B M
BM
D001772:Blood Cell Count; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000097:blood; D004573:Electrolytes / Q000097:blood; D005260:Female; D006801:Humans; D007223:Infant; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008111:Liver Function Tests; D016779:Malaria, Cerebral / Q000097:blood / Q000378:metabolism* / Q000401:mortality; D008297:Male; D014508:Urea / Q000097:blood
D004573:Electrolytes; D014508:Urea; D003404:Creatinine