Ketoacidosis and hyperosmolarity as first symptoms of type 1 diabetes mellitus following ingestion of high-carbohydrate-containing fluids.
The concomitant occurrence of diabetic ketoacidosis and hyperosmolarity is reported in two children, as early symptoms of misdiagnosed type 1 diabetes mellitus. The precipitating factor for both severe metabolic abnormalities was the ingestion of a large amount of high-carbohydrate-containing fluids, a few days before admission. A similar situation has never been reported before in the literature. A successful therapeutic scheme is described.
Vanelli
M
M
Department of Pediatrics, University of Parma, Italy.
Chiari
G
G
Ghizzoni
L
L
Capuano
C
C
Bonetti
L
L
Costi
G
G
Giacalone
T
T
Chiarelli
F
F
D001786:Blood Glucose / Q000378:metabolism; D002241:Carbohydrates; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis* / Q000628:therapy; D016883:Diabetic Ketoacidosis / Q000139:chemically induced / Q000378:metabolism* / Q000628:therapy; D005440:Fluid Therapy; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use; D007332:Insulin Infusion Systems; D008297:Male; D012996:Solutions; D014883:Water-Electrolyte Imbalance / Q000139:chemically induced / Q000378:metabolism* / Q000628:therapy
D001786:Blood Glucose; D002241:Carbohydrates; D007004:Hypoglycemic Agents; D007328:Insulin; D012996:Solutions