Modulation of intramacrophage iron metabolism during microbial cell invasion.
The mechanisms whereby vertebrate hosts withhold iron from microbial invaders, as well as the methods used in attempts by invaders to capture the growth-essential metal, differ between host extracellular and intracellular environments. This review focuses on procedures employed by host cells and by invaders, respectively, that alter intramacrophage iron metabolism.
Weinberg
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Department of Biology, Indiana University, Bloomington 47405, USA.
D000818:Animals; D001419:Bacteria / Q000254:growth & development*; D001424:Bacterial Infections / Q000378:metabolism* / Q000382:microbiology; D002352:Carrier Proteins / Q000378:metabolism; D027682:Cation Transport Proteins; D006801:Humans; D007501:Iron / Q000378:metabolism*; D008264:Macrophages / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism; D009569:Nitric Oxide / Q000378:metabolism; D000099173:Natural Resistance-associated Macrophage Protein 1
D002352:Carrier Proteins; D027682:Cation Transport Proteins; D007501:Iron; D008565:Membrane Proteins; D009569:Nitric Oxide; D000099173:Natural Resistance-associated Macrophage Protein 1