title: Aetiology of childhood vision impairment, metropolitan Atlanta, 1991-93.
abstract: Data from the population-based Metropolitan Atlanta Developmental Disabilities Surveillance Program (MADDSP) were used to describe the underlying causes of vision impairment (VI; corrected visual acuity in the better eye of 20/70 or worse) in young children (n = 228) in metropolitan Atlanta in 1991-93. Children with VI were identified through record review at multiple educational and medical sources. Children were categorised as having isolated VI or multiple disabilities (i.e. VI plus one or more of four additional developmental disabilities) and as having low vision (visual acuity 20/70-20/400) or blindness (visual acuity worse than 20/400). Medical conditions abstracted from MADDSP sources were reviewed to determine the probable aetiology of a child's VI. Aetiologies were assigned to one of three developmental time periods: prenatal, perinatal, or postnatal. Prenatal aetiologies were identified in 43% of the children; 38% of the prenatal aetiologies were genetic. Perinatal aetiologies were found in 27% of the children. Postnatal aetiologies were rare. Prenatal aetiologies were more common in children with isolated VI; perinatal and postnatal aetiologies were more common in children with multiple disabilities. Children with prenatal aetiologies tended to have less severe vision loss than did children with perinatal or postnatal aetiologies. The distribution varied by birthweight, but did not differ significantly by sex or race.
authors.affiliation: Developmental Disabilities Branch, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA. czm4@cdc.gov
authors.forename: C A
authors.initials: CA
authors.lastname: Mervis
authors.forename: M
authors.initials: M
authors.lastname: Yeargin-Allsopp
authors.forename: S
authors.initials: S
authors.lastname: Winter
authors.forename: C
authors.initials: C
authors.lastname: Boyle
mesh_terms: D000015:Abnormalities, Multiple / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005845:Georgia / Q000453:epidemiology; D006801:Humans; D008297:Male; D014786:Vision Disorders / Q000151:congenital / Q000453:epidemiology / Q000209:etiology*