A review of variables affecting PTs/INRs.
The prothrombin time is a common method of monitoring patients undergoing oral anticoagulant therapy. The proliferation of commercial thromboplastin brands with different international sensitivity indices (ISI) in conjunction with wider availability of automated coagulation analyzers has elevated the need for standardization in monitoring therapy.
McGlasson
D L
DL
MS CLS/NCA, 59th MDW/MSRL, 59th Clinical Research Squadron, Lackland AFB, TX 78236-5319, USA. davemcglasson@hotmail.com
D000925:Anticoagulants / Q000627:therapeutic use*; D006801:Humans; D007202:Indicators and Reagents / Q000592:standards; D019934:International Normalized Ratio; D011517:Prothrombin Time; D013925:Thromboplastin / Q000592:standards
D000925:Anticoagulants; D007202:Indicators and Reagents; D013925:Thromboplastin