Antihyperglycemic activity of Teramnus labialis (Fabaceae).
In vivo bioassay-guided fractionation of the aqueous alcohol extract of the aerial parts of Teramnus labialis (Roxb.) Benth. (Fabaceae), using C57BL/Ks-db/db mice as a model for type 2 diabetes, yielded an active fraction containing a mixture of coumarins. The major coumarin present in the active fraction was identified as fraxidin.
Fort
D M
DM
Shaman Pharmaceuticals, South San Francisco, CA, USA. dfort@pharmanex.com
Rao
K
K
Jolad
S D
SD
Luo
J
J
Carlson
T J
TJ
King
S R
SR
D000818:Animals; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats
D007004:Hypoglycemic Agents; D010936:Plant Extracts