[Chemical toxicological analysis of urinary cannabinoids by chromatography mass spectrometry].
A chromato-mass-spectrometric method for identification of cannabinoids and 9-carboxy-11-nor-delta 9-tetrahydrocannabinol by their methyl derivatives is proposed. Use of alkaline hydrolysis in pretreatment of samples ensures the optimal conditions for complete isolation of 9-carboxy-11-nor-delta 9-tetrahydrocannabinol. Derivation with methyl iodide in absolute acetone in the presence of potassium carbonate was used. Preliminary conclusion on the presence of cannabinoids in the urine can be made from the results of enzyme immunoassay.
Kataev
S S
SS
Smirnova
I Iu
IIu
Zalesova
V A
VA
Kurdina
L N
LN
D000096:Acetone; D002186:Cannabinoids / Q000032:analysis*; D002254:Carbonates; D013759:Dronabinol / Q000031:analogs & derivatives / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D006847:Hydrocarbons, Iodinated; D011188:Potassium; D014556:Urine / Q000737:chemistry*
D002186:Cannabinoids; D002254:Carbonates; D006847:Hydrocarbons, Iodinated; D000096:Acetone; C016780:11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid; D013759:Dronabinol; C037593:potassium carbonate; C014055:methyl iodide; D011188:Potassium