Inactivation of human type A and B influenza viruses by tea-seed saponins.
The effects of a mixture of tea-seed saponins obtained from the seeds of Camellia sinensis var. sinesis on human influenza viruses types A and B were investigated. At the concentrations of 60, 80, and 100 micrograms/ml, respectively, the mixture inactivated viruses A/Memphis/1/71 (H3N2), B/Lee/40, and A/PR/8/34 (H1N1) almost completely. The mixture also inactivated type A virus A/PR/8/34 after inoculation at concentrations of 1-30 micrograms/ml dose-dependently.
Hayashi
K
K
Central Research Institute, Ito En Ltd., Shizuoka, Japan. ITN00535@nifty.ne.jp
Sagesaka
Y M
YM
Suzuki
T
T
Suzuki
Y
Y
D000818:Animals; D002460:Cell Line; D004285:Dogs; D006801:Humans; D009980:Influenza A virus / Q000187:drug effects*; D009981:Influenza B virus / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology; D012503:Saponins / Q000494:pharmacology*; D012639:Seeds / Q000737:chemistry; D013662:Tea / Q000737:chemistry*
D010936:Plant Extracts; D012503:Saponins; D013662:Tea