title: [Extrahepatic manifestations of hepatitis C virus].
abstract: ACCEPTED ASSOCIATIONS: Extrahepatic manifestations of the hepatitis C virus (HCV) have been reported in a large body of literature. It is now generally accepted that the HCV is strongly associated with so-called essential cryoglobulinemia, membrane proliferative glomerulonephritis with or without cryoglobulinemia, sporadic porphyria cutanea tarda, and with lymphocyte sialadenitis with or without a dry mouth syndrome. PROBABLE ASSOCIATIONS: Several epidemiological arguments suggest that HCV could play a role in certain types of non-Hodgkin lymphomas. HCV is also sometimes implicated in periarteritis nodosa and with peripheral neuropathies with lymphocyte vasculitis. UNPROVEN ASSOCIATIONS: The role of HCV in autoimmune dysthyroidism, lichen planus, diabetics mellitus, and antiphospholipid syndromes is a subject of debate. There have also many sporadic reports of manifestations of syndromes suggesting, though not proving, an association with the hepatitis C virus.
authors.affiliation: Service de Médecine interne, Hôpital Avicenne, Bobigny.
authors.forename: P
authors.initials: P
authors.lastname: Cohen
mesh_terms: D016736:Antiphospholipid Syndrome / Q000209:etiology; D003449:Cryoglobulinemia / Q000209:etiology*; D003920:Diabetes Mellitus / Q000209:etiology; D015432:Glomerulonephritis, Membranoproliferative / Q000209:etiology*; D006526:Hepatitis C / Q000150:complications* / Q000276:immunology; D019698:Hepatitis C, Chronic / Q000150:complications; D006801:Humans; D008010:Lichen Planus / Q000209:etiology; D008228:Lymphoma, Non-Hodgkin / Q000209:etiology; D010523:Peripheral Nervous System Diseases / Q000209:etiology; D010488:Polyarteritis Nodosa / Q000209:etiology; D017119:Porphyria Cutanea Tarda / Q000209:etiology*; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D012793:Sialadenitis / Q000209:etiology*; D013967:Thyroiditis, Autoimmune / Q000209:etiology; D014657:Vasculitis / Q000209:etiology