title: Cortical development: receiving reelin.
abstract: Recent genetic and biochemical studies indicate that lipoprotein receptors are components of the neuronal receptor for Reelin, mediating the glycoprotein's essential function in cortical development. At least eight cadherin-related neuronal receptors may also play a part in this signalling system.
authors.affiliation: Department of Neuroscience, Case Western Reserve University Medical School/University Hospitals of Cleveland, Cleveland, Ohio 44106, USA. kxh26@po.cwru.edu
authors.forename: E C
authors.initials: EC
authors.lastname: Gilmore
authors.forename: K
authors.initials: K
authors.lastname: Herrup
mesh_terms: D000818:Animals; D053329:Apolipoprotein E2; D001057:Apolipoproteins E / Q000378:metabolism; D015820:Cadherins / Q000378:metabolism; D015816:Cell Adhesion Molecules, Neuronal / Q000378:metabolism*; D016326:Extracellular Matrix Proteins / Q000378:metabolism*; D008079:Lipoproteins, VLDL / Q000378:metabolism; D051379:Mice; D008818:Mice, Neurologic Mutants; D019579:Neocortex / Q000196:embryology*; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D009479:Neuropeptides / Q000378:metabolism; D000091363:Protocadherins; D011956:Receptors, Cell Surface; D000091042:Reelin Protein; D012697:Serine Endopeptidases
chemical_list: D053329:Apolipoprotein E2; D001057:Apolipoproteins E; D015820:Cadherins; D015816:Cell Adhesion Molecules, Neuronal; D016326:Extracellular Matrix Proteins; D008079:Lipoproteins, VLDL; D009419:Nerve Tissue Proteins; D009479:Neuropeptides; C113143:Pcdha4 protein, mouse; D000091363:Protocadherins; D011956:Receptors, Cell Surface; D000091042:Reelin Protein; C000717128:Reln protein, mouse; D012697:Serine Endopeptidases