title: Chemotherapeutic malaria control as a selective primary health care activity in the Solomon Islands.
abstract: Malaria control by chemotherapy has been established in rural villages of Guadalcanal, the Solomon Islands, following field trials. As a selective primary health care activity, mobile unit teams visited villages once or twice a year to detect malaria positives and gave chloroquine and primaquine to treat the infection and interrupt the transmission. On site diagnosis was by the use of acridine orange fluorescent staining or the ICTPf commercial diagnostic kit. To avoid possible haemolytic crises, a new single step screening method of G6PD deficiency was introduced. This approach has been accepted well by villagers and proved to be an efficient and feasible control method even in remote rural villages with endemic malaria transmission. Epidemiological modelling of the situation predicts reduction of prevalence in five years.
authors.affiliation: Department of Medical Zoology, Jichi Medical School, Tochigi, Japan. ishiiaki@jichi.ac.jp
authors.forename: A
authors.initials: A
authors.lastname: Ishii
authors.forename: N
authors.initials: N
authors.lastname: Nagai
authors.forename: M
authors.initials: M
authors.lastname: Arai
authors.forename: M
authors.initials: M
authors.lastname: Kawabata
authors.forename: T
authors.initials: T
authors.lastname: Matsuo
authors.forename: A
authors.initials: A
authors.lastname: Bobogare
authors.forename: J
authors.initials: J
authors.lastname: Leafasia
mesh_terms: D000328:Adult; D000962:Antimalarials / Q000627:therapeutic use*; D002648:Child; D002738:Chloroquine / Q000627:therapeutic use; D006801:Humans; D008288:Malaria / Q000188:drug therapy* / Q000453:epidemiology / Q000635:transmission; D008542:Melanesia / Q000453:epidemiology; D011319:Primaquine / Q000627:therapeutic use; D011322:Primary Prevention; D011933:Reagent Kits, Diagnostic
chemical_list: D000962:Antimalarials; D011933:Reagent Kits, Diagnostic; D002738:Chloroquine; D011319:Primaquine