[The pathogenesis of achlorhydria of the operated stomach and the functionally optimal volumes for distal resection in areflux gastrointestinal anastomosis].
Examinations of 68 patients after operations of selective proximal vagotomy and 59 patients after the Billroth-II and Roux resections were performed within the periods of about 16 years. It was found that reflux was of main significance in the genesis of achlorhydria of the operated stomach. Gastric changes caused by Helicobacter pylori did not result in so rapid suppression of functional activity of the operated stomach. Hemiresection is thought to be optimal for the areflux Roux gastrojejunal anastomosis with hypersecretion. In patients with normal secretion a resection of 2/3 of the stomach is expedient. In cases with hypersecretion and unknown boundaries of the antrum a resection of 50-60% of the stomach must be supplemented with vagotomy.
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D000126:Achlorhydria / Q000209:etiology*; D000714:Anastomosis, Surgical / Q000379:methods / Q000706:statistics & numerical data; D004383:Duodenogastric Reflux / Q000517:prevention & control*; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000379:methods* / Q000706:statistics & numerical data; D005745:Gastric Acidity Determination; D005753:Gastric Mucosa / Q000378:metabolism; D016481:Helicobacter Infections / Q000503:physiopathology; D016480:Helicobacter pylori; D006801:Humans; D011183:Postoperative Complications / Q000209:etiology*; D013997:Time Factors; D014629:Vagotomy, Proximal Gastric / Q000706:statistics & numerical data