title: Intralesional laser therapy of extensive hemangiomas in 100 consecutive pediatric patients.
abstract: The authors have treated 100 consecutive pediatric patients with capillary/cavernous hemangiomas (age range, 1.3 months to 16 years; mean age, 26.6 months; 30 male and 70 female patients) with intralesional laser therapy during a 3-year period. All patients have been followed for a minimum of 6 months after treatment (range, 6-36 months; mean, 18 months). Indications for intralesional laser treatment included interference with vision, blockage of the nose or mouth, ulceration, bleeding, and rapid, uncontrollable growth. The Nd:YAG laser was used in 70 patients, and the Potassium, Titanyl, Phosphate (KTP) laser was used in 30 patients. Fifty-five hemangiomas were in the head and neck region, excluding the orbit; 25 were in the trunk or extremities; 10 were periorbital; and 10 involved multiple sites. Seventy patients (70%) received one treatment, 20 patients (20%) received two treatments, 7 patients (7%) received three treatments, and 3 patients (3%) received four or more treatments. No appreciable differences were noted between treatment with the Nd:YAG and KTP lasers. Forty-six patients had more than a 90% reduction in the overall size of the hemangiomas whereas 54 patients had a 50% to 90% reduction in the size of the hemangioma. After maximal reduction in size of the cavernous component was achieved, the external capillary component, found in 68 patients, was treated with a tunable dye laser. Seventy-six patients underwent surgical resection after maximal lesion involution. Residual induration due to lesion fibrosis was treated with local steroid injections in 13 patients. There were four operative complications attributable to intralesional laser therapy. Two patients had residual midfacial weakness, and two patients had punctuated skin burns after intralesional treatment. The authors have found intralesional laser therapy to be a valuable tool in the treatment of large capillary/cavernous hemangiomas, often rendering an inoperable lesion safely resectable, or markedly decreasing the size and functional impact of the lesion.
authors.affiliation: The Center for Craniofacial Disorders, Scottish Rite Children's Medical Center, Atlanta, GA 30342, USA.
authors.forename: F D
authors.initials: FD
authors.lastname: Burstein
authors.forename: C
authors.initials: C
authors.lastname: Simms
authors.forename: S R
authors.initials: SR
authors.lastname: Cohen
authors.forename: J K
authors.initials: JK
authors.lastname: Williams
authors.forename: M
authors.initials: M
authors.lastname: Paschal
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D018324:Hemangioma, Capillary / Q000601:surgery / Q000628:therapy*; D006392:Hemangioma, Cavernous / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007223:Infant; D053685:Laser Therapy; D008297:Male; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures; D016896:Treatment Outcome