title: [Fragmentation of hydrogel episcleral implants: a series of 4 cases].
abstract: A histopathologic study was performed on 4 capsule specimens obtained after surgical removal of hydrogel episcleral implant previously sutured to the scleral surface aiming to reattach the retina. Fragments of hydrogel were found on the inner surface of the capsular fragments, each of them parts of the capsule, which coated the hydrogel implant on the scleral surface. Some fragments were surrounded with a foreign body giant cell granulomatous reaction. Changes in scleral curvature and scleral thinning were consequences of the buckling procedure. The hydrogel fragmentation previously observed in experimental and human specimens gave histologic evidence of degradation of this material after its implantation on the eye surface. This characteristic demonstrates the instability of the material after implantation.
authors.affiliation: Laboratoire d'Ophtalmologie, Service d'Ophtalmologie, Hôtel-Dieu, 1, place du Parvis de Notre-Dame F 75181 Paris Cedex 04.
authors.forename: F
authors.initials: F
authors.lastname: D'hermies
authors.forename: J
authors.initials: J
authors.lastname: Korobelnik
authors.forename: S
authors.initials: S
authors.lastname: Bertin
authors.forename: D
authors.initials: D
authors.lastname: Chauvaud
authors.forename: G
authors.initials: G
authors.lastname: Renard
authors.forename: J
authors.initials: J
authors.lastname: Audouin
authors.forename: J
authors.initials: J
authors.lastname: Diebold
authors.forename: A
authors.initials: A
authors.lastname: Duprez
mesh_terms: D000328:Adult; D000368:Aged; D019544:Equipment Failure Analysis; D005260:Female; D005549:Foreign-Body Reaction / Q000209:etiology* / Q000473:pathology; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology* / Q000473:pathology; D012163:Retinal Detachment / Q000473:pathology / Q000601:surgery*; D012590:Sclera / Q000473:pathology; D012591:Scleral Buckling / Q000295:instrumentation*
chemical_list: D020136:Hydrogel, Polyethylene Glycol Dimethacrylate