Alpha blocker prazosin for the treatment of benign prostatic hypertrophy (BPH).
In this study medical treatment with alpha blocker-prazosin is compared with transurethral resection of prostate (TURP) in 62 patients suffering from benign enlargement of prostate with a gland size of less than 20 gms. After thorough interrogation patients were offered either TURP or prazosin therapy. Symptom scoring, residual volume of urine and urinary flow rates were estimated in both the groups before and 3 months after the therapy. 23.5% patients in prazosin group while 90% of patients in TURP group had significant improvement. This distinctly brings out the superiority of TURP for benign enlargement of prostate.
Punekar
S V
SV
Department of Urology, KEM and Seth GS Medical College Hospital, Parel, Mumbai.
Kelkar
A R
AR
Gavande
P M
PM
Rao
N R
NR
Date
J A
JA
Prem
A R
AR
D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011224:Prazosin / Q000627:therapeutic use*; D011470:Prostatic Hyperplasia / Q000188:drug therapy* / Q000601:surgery; D020728:Transurethral Resection of Prostate; D016896:Treatment Outcome; D014554:Urination / Q000502:physiology
D000317:Adrenergic alpha-Antagonists; D011224:Prazosin