Cure from severe aplastic anemia in vivo and late effects.
Recent progress in the treatment of aplastic anemia has dramatically changed the previously grim prognosis for these patients. Improvements in bone marrow transplantation and immunosuppression have increased the number of long-term survivors so that immediate survival is no longer the sole concern. Here, were review the major clinical studies and summarize recent analyses of late malignant and nonmalignant complications following treatment of aplastic anemia.
Socié
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Service d'Hématologie-Greffe de Moelle, Hôpital Saint-Louis, Paris, France.
Gluckman
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D000741:Anemia, Aplastic / Q000150:complications / Q000401:mortality / Q000628:therapy*; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D009369:Neoplasms / Q000209:etiology*; D011379:Prognosis; D015996:Survival Rate