title: Reversed-phase liquid chromatographic column switching for the determination of N-methylcarbamates and some of their main metabolites in urine.
abstract: A column switching system for the determination of some polar pesticides and their main metabolites, such as aldicarb, aldicarb sulphoxide, aldicarb sulphone, carbofuran and 3-hydroxicarbofuran, in human urine has been developed. The limits of detection were between 0.3 and 1 microg/l. We used a simple solid-phase extraction with graphite carbon and a RPLC-LC analysis with UV detection yielding average recoveries between 84 and 110% (N=5) with RSD between 4 and 8%.
authors.affiliation: Department of Analytical Chemistry, University of Almería, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Parilla Vázquez
authors.forename: J L
authors.initials: JL
authors.lastname: Martínez Vidal
authors.forename: J
authors.initials: J
authors.lastname: Martínez Fernández
mesh_terms: D002219:Carbamates / Q000652:urine*; D002853:Chromatography, Liquid / Q000379:methods*; D006801:Humans; D007306:Insecticides / Q000633:toxicity*; D016273:Occupational Exposure; D012680:Sensitivity and Specificity
chemical_list: D002219:Carbamates; D007306:Insecticides; C020401:N-methylcarbamate