Novel chromosomal insertional translocation in chicken uncovered by double color FISH.
A novel insertion 78,ZZ or 78,ZW, ins(3;1)(q25q27;undetermined) was revealed in chicken by double color fluorescent in situ hybridization (FISH). A fragment of chromosome 1 spanning either from q13-14 to q34-35, or from q14-21 to q36-41 bands, had been translocated to chromosome 3 at a site located between q25 to q27 bands. This has resulted in the generation of an interstitial deletion in chromosome 1 and an insertional translocation in chromosome 3. Chickens with this balanced insertional translocation are asymptomatic carriers and their fertility is not affected, but embryo mortality increases. Greater than 50% occurrence of unbalanced gametes are observed. However, progeny sex ratio is not affected.
Ramos
P S
PS
Department of Animal Sciences, University of Minnesota, St. Paul 55108, USA.
Bitgood
J J
JJ
Ponce de León
F A
FA
D000818:Animals; D002645:Chickens / Q000235:genetics*; D002874:Chromosome Mapping; D004625:Embryo, Nonmammalian; D005298:Fertility; D017404:In Situ Hybridization, Fluorescence / Q000379:methods*; D016254:Mutagenesis, Insertional; D014178:Translocation, Genetic / Q000235:genetics*