[The activities of some glycosaminoglycan degrading enzymes in the wall of the umbilical cord vein and their alteration in EPH-gestosis].
EPH-gestosis evokes great connective tissue rebuilding in the wall of umbilical cord arteries and Wharton's jelly. Not much is known about umbilical cord vein maintenance. For better understanding of processes proceeding in it we decided to determine activities of some glycosaminoglycan-degrading enzymes. It was found that specific activities of some neutral endoglycosidases and exoglycosidases decreased during EPH-gestosis. Acidic endoglycosidases and sulphatases specific activities did not change. Those results with no changes in content and proportional relationship of umbilical cord vein glycosaminoglycans suggest that EPH-gestosis disturbs markedly those connective tissue element metabolism.
Romanowicz
L
L
ZakładuBiochemii AM w Białymstoku.
Jaworski
S
S
D000328:Adult; D003238:Connective Tissue / Q000201:enzymology; D005260:Female; D006025:Glycosaminoglycans / Q000378:metabolism*; D006801:Humans; D017038:Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase / Q000378:metabolism*; D011225:Pre-Eclampsia / Q000201:enzymology*; D011247:Pregnancy; D013429:Sulfatases / Q000378:metabolism*; D014470:Umbilical Cord / Q000201:enzymology*
D006025:Glycosaminoglycans; D013429:Sulfatases; D017038:Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase