Cell death: drosophila Apaf-1 - no longer in the (d)Ark.
The recent discovery and characterization of Ark, the Drosophila homolog of the mammalian cell-death adaptor protein Apaf-1, have revealed that, like Apaf-1, this protein is important in multiple apoptosis pathways. The new findings also suggest that cell death in flies is very similar to that in mammals after all.
White
K
K
Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA. kristin.white@CBRC2.MGH.Harvard.edu
D000818:Animals; D017209:Apoptosis; D053477:Apoptotic Protease-Activating Factor 1; D029721:Drosophila Proteins; D004331:Drosophila melanogaster; D011506:Proteins / Q000502:physiology*
D053477:Apoptotic Protease-Activating Factor 1; D029721:Drosophila Proteins; D011506:Proteins; C400550:dark protein, Drosophila