title: Pathology of the heart and conduction system in a case of sudden death due to a cardiac fibroma in a 6-month-old child.
abstract: A 6-month-old female infant considered to be in good health died suddenly and unexpectedly. Post-mortem examination was requested, with clinical diagnosis of sudden infant death syndrome. Gross examination revealed, however, the presence of a cardiac mass 4.5 X 4 x 3.5 cm in diameter. Histological examination of the heart confirmed the presence of a cardiac fibroma. In the present case, the sudden death could have been due to the left ventricular outflow obstruction, as much as to conductive disturbances caused by overstretching and compression of the atrioventricular node and of the bundle branches. Hemodynamic and conductive abnormalities are presumed to have provoked bradycardia degenerating into ventricular fibrillation and sudden death. Necroscopy studies of sudden death should always include histological examination of the cardiac conduction system but seldom do.
authors.affiliation: Institute of Pathology, University of Study of Milan, IRCCS, Ospedale Maggiore, Milano, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Ottaviani
authors.forename: L
authors.initials: L
authors.lastname: Rossi
authors.forename: S G
authors.initials: SG
authors.lastname: Ramos
authors.forename: L
authors.initials: L
authors.lastname: Matturri
mesh_terms: D005260:Female; D005350:Fibroma / Q000150:complications / Q000473:pathology*; D006329:Heart Conduction System / Q000473:pathology*; D006338:Heart Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D007223:Infant; D013398:Sudden Infant Death / Q000209:etiology*