title: Influence of individual differences in craving and obsessive cocaine thoughts on attentional processes in cocaine abuse patients.
abstract: In the present pilot-study, the relation between craving, obsessive thoughts about cocaine, experienced control, and attentional bias for cocaine related words is investigated. Sixteen cocaine abuse patients participated in a reaction time (RT) experiment which was employed to measure the ability of subjects to shift their attention away from cocaine related words. Postexperiment craving was found to be positively correlated with reaction times on drug related cues, in contrast to RT on neutral cues. Furthermore, obsessive thoughts about cocaine use and the experienced cocaine use control, in the week before the experiment, were correlated in a higher degree with RTs on drug cues than postexperiment craving. Attentional bias for drug cues was evidenced in patients with higher scores on obsessive cocaine thoughts and higher craving scores. This study shows that individual differences on information processing, within a cocaine abuse patient population, are present.
authors.affiliation: Parnassia Research Centre--Addiction Department, The Hague, The Netherlands. ifranken@parnassia.nl
authors.forename: I H
authors.initials: IH
authors.lastname: Franken
authors.forename: L Y
authors.initials: LY
authors.lastname: Kroon
authors.forename: V M
authors.initials: VM
authors.lastname: Hendriks
mesh_terms: D000328:Adult; D001143:Arousal / Q000187:drug effects; D001288:Attention / Q000187:drug effects*; D003042:Cocaine / Q000009:adverse effects; D019970:Cocaine-Related Disorders / Q000523:psychology* / Q000534:rehabilitation; D005260:Female; D006778:Hospitals, Psychiatric; D006801:Humans; D007206:Individuality; D007389:Internal-External Control; D008297:Male; D009042:Motivation; D010343:Patient Admission; D011930:Reaction Time / Q000187:drug effects; D013375:Substance Withdrawal Syndrome / Q000523:psychology; D013850:Thinking / Q000187:drug effects*
chemical_list: D003042:Cocaine