title: [A case of acute diffuse atrophy of retinal pigment epithelium].
abstract: OBJECTIVE
  To report a case of acute bilateral visual disturbance where the ocular fundus changed like retinitis pigmentosa in a short time.
  
  
  METHODS
  26-year-old man.
  
  
  RESULTS
  In initial examination, the patient's visual acuity was 0.01 OD and 0.02 OS with myopic correction, but his fundus did not look abnormal. Fluorescein angiogram showed marked background hyperfluorescence and dye leaking to the vitreous. After 2-3 weeks, the fundus appearance changed like retinitis pigmentosa. Best corrected visual acuity became 1.0 OD and 0.9 OS after steroid pulse therapy. We were unable to find the cause of this disease in spite of blood tests and other examinations.
  
  
  CONCLUSIONS
  This case with acute diffuse atrophy of retinal pigment epithelium and damage of the function of blood-retinal barrier was considered remarkably rare.
authors.affiliation: Department of Ophthalmology, Tohoku University School of Medicine, Sendai, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Yamashita
authors.forename: Y
authors.initials: Y
authors.lastname: Nakagawa
authors.forename: M
authors.initials: M
authors.lastname: Tamai
mesh_terms: D000208:Acute Disease; D000328:Adult; D001284:Atrophy; D006801:Humans; D008297:Male; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012174:Retinitis Pigmentosa / Q000473:pathology