An electrophysiological follow-up study on acquired unilateral nyctalopia.
OBJECTIVE
To describe the clinical picture and electrophysiological findings in acquired unilateral nyctalopia.


METHODS
A patient who had acquired unilateral visual loss with normal fundus was followed for a period of 2.5 years with basic ophthalmological examinations including standard electroretinogram and photopic on and off responses.


RESULTS
A 46-year-old woman suffered from acquired unilateral nyctalopia. She complained of photopsia and blurred vision in her left eye. The initial examination of the left eye showed 1+ cells in the anterior chamber and a granular appearance in the fovea. After 1 month of treatment she still complained of photopsia in her left eye. Ophthalmoscopy and fluorescein angiography revealed no abnormality in either eye. A bright flash electroretinogram (ERG) in the left eye was a negative shape. Photopic ERG elicited by a 150 ms stimulus showed a depressed b-wave and enhanced a- and d-waves in the left eye.


CONCLUSIONS
This ERG waveform suggested that the transmission between photoreceptor and on-bipolar cell might be affected by idiopathic retinal disease.
Murayama
K
K
Department of Ophthalmology, Saitama Medical School, Japan. koichiro@saitama.ac.jp
Kawabata
H
H
Adachi-Usami
E
E
D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009755:Night Blindness / Q000503:physiopathology*; D010775:Photic Stimulation