Transplantation of three adult patients with one cadaveric graft: wait or innovate.
Graft shortage continues to prolong waiting times for adults requiring liver transplantation. Living related donor transplantation is possible for only a small minority of adults. The techniques for in situ splitting of the liver used for right and left hepatectomies in living donors were adapted to a combined split-liver-domino procedure to obtain right and left hemiliver grafts from a patient undergoing total hepatectomy with liver transplantation for a metabolic disorder. The two grafts were adequate in size and function for transplantation to two adults with low priority for regular cadaver grafts. More frequent use of split-liver techniques in cadaver donors could considerably reduce the graft shortage and waiting time for adult liver recipients.
Azoulay
D
D
Centre Hépatobiliaire, Hôpital Paul Brousse, Université de Paris Sud and Assistance Publique-Hôpitaux de Paris, Villejuif, France.
Castaing
D
D
Adam
R
R
Mimoz
O
O
Bismuth
H
H
D000328:Adult; D002102:Cadaver; D006528:Carcinoma, Hepatocellular / Q000601:surgery*; D006801:Humans; D008103:Liver Cirrhosis / Q000601:surgery*; D008113:Liver Neoplasms / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods*