Postpartum microangiopathic hemolytic anemia: cases of successful and dismal outcome assisted with plasma therapy.
Microangiopathic thrombosis, thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS), seem to occur with certain stresses, including pregnancy. This report documents the clinical outcome with or without plasma therapy and dismal outcomes of two cases with postpartum microangiopathic thrombosis. One carried a pregnancy to successful cesarean delivery and suffered from postpartum TTP/HUS followed by plasma therapy-assisted recovery. Another developed postpartum TTP/HUS and was complicated with subarachnoid hemorrhage. Submission to plasma therapy should always be considered in a woman with postpartum microangiopathic thrombosis.
Takahashi
Y
Y
Department of Obstetrics and Gynecology, Gifu University School of Medicine, Tsukasamachi, Gifu, Japan. y-taka@cc.gifu-u.ac.jp
Imai
A
A
Hayasaki
Y
Y
Kawabata
I
I
Tamaya
T
T
D000328:Adult; D001803:Blood Transfusion; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000628:therapy*; D006801:Humans; D010951:Plasma Exchange; D011247:Pregnancy; D011644:Puerperal Disorders / Q000628:therapy*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000628:therapy*; D013927:Thrombosis / Q000628:therapy*