Dietary fat and fish intake and age-related maculopathy.
OBJECTIVE
To assess whether dietary intake of fat or fish is associated with age-related maculopathy (ARM) prevalence.


METHODS
Cross-sectional, urban population-based study.


METHODS
People (N = 3654) aged 49 years or older.


METHODS
Subjects with ARM were identified from masked grading of retinal photographs. A 145-itemself-administered, semiquantitative food frequency questionnaire was completed adequately by 88.8% of participants and was used to assess intakes of dietary fat and fish.


RESULTS
A higher frequency of fish consumption was associated with decreased odds of late ARM (odds ratio for frequency of consumption more than once per week compared with less than once per month, 0.5). Subjects with higher energy-adjusted intakes of cholesterol were significantly more likely to have late ARM, with an increased risk for late ARM for the highest compared with the lowest quintile of intake (odds ratio, 2.7).


CONCLUSIONS
The amount and type of dietary fat intake may be associated with ARM.
Smith
W
W
National Centre for Epidemiology and Population Health, Australian National University, Australian Capital Territory. wayne.smith@anu.edu.au
Mitchell
P
P
Leeder
S R
SR
D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D004041:Dietary Fats / Q000008:administration & dosage*; D004435:Eating; D002149:Energy Intake; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D009517:New South Wales / Q000453:epidemiology; D009749:Nutrition Surveys; D017747:Seafood
D004041:Dietary Fats; D015525:Fatty Acids, Omega-3