title: What is the definition of cure for aplastic anemia?
abstract: Treatment with immune suppression and bone marrow transplantation has improved the response rates and survival of patients with aplastic anemia. Measurement of response requires that common endpoints be recorded at specific times. There has been no agreement on such parameters for patients with aplastic anemia. In this paper issues related to measurement of response are reviewed and criteria for response are proposed. Adoption of uniform criteria would facilitate comparisons of treatment efficacy.
authors.affiliation: Midwest Children's Cancer Center, Department of Pediatrics, Medical College of Wisconsin and the Children's Hospital of Wisconsin, Milwaukee, WI 53226, USA. bcamitta@mcw.edu
authors.forename: B M
authors.initials: BM
authors.lastname: Camitta
mesh_terms: D000741:Anemia, Aplastic / Q000401:mortality / Q000628:therapy*; D016026:Bone Marrow Transplantation; D018572:Disease-Free Survival; D006801:Humans; D007165:Immunosuppression Therapy; D015996:Survival Rate; D016896:Treatment Outcome