[Median nerve evoked potentials and explicit memory function during recovery from propofol-sufentanil anesthesia].
OBJECTIVE
In a prospective study rnidlatency somatosensory evoked Potentials (SEP) were investigated in relation to explicit memory function during recovery from propofol/sufentanil anaesthesia.


METHODS
Anaesthesia was maintained in 20 patients with 8 mg kg-1 h-1 propofol and supplemented with sufentanil. SEPs (N20, P25, N35, P45 N50) elicited by median nerve stimulation were recorded at the day before surgery (AWAKE) and during recovery from anaesthesia, when patients were able to identify a shown object (RECOVERY). The day after surgery patients were interviewed about their memory of the recovery period.


METHODS
Hotellings' T2.


RESULTS
One day after anaesthesia 9 patients could remember events during the recovery period. At RECOVERY SEP-latencies P45 and N50 were significantly shorter in the patients with recall for the wakeup-phase (p < 0.05).


CONCLUSIONS
SEP latencies P45 and N50 indicated impaired explicit memory function during recovery from propofol/sufentanil anaesthesia.
Rundshagen
I
I
Klinik für Anästhesiologie, Universitäts-Krankenhaus Eppendorf, Hamburg.
Schnabel
K
K
Schulte am Esch
J
J
D000328:Adult; D000762:Anesthesia Recovery Period; D000771:Anesthesia, Intravenous; D018686:Anesthetics, Intravenous; D005073:Evoked Potentials, Somatosensory / Q000187:drug effects*; D005260:Female; D006801:Humans; D008475:Median Nerve / Q000502:physiology*; D008568:Memory / Q000187:drug effects*; D008875:Middle Aged; D015742:Propofol; D017409:Sufentanil
D018686:Anesthetics, Intravenous; D017409:Sufentanil; D015742:Propofol