title: Increase in sensitization to oil of turpentine: recent data from a multicenter study on 45,005 patients from the German-Austrian Information Network of Departments of Dermatology (IVDK).
abstract: Contact allergy to oil of turpentine was reported to have become rare. However, the evaluation of standardized data of 45,005 patients tested 1992-1997 in 30 Dermatological Centers associated with the German-Austrian Information Network of Departments of Dermatology (IVDK) showed an increase in positive patch test reactions to turpentine from 0.5% during the years 1992-1995, up to 1.7% in 1996 and 3.1% in 1997. In particular, 17,347 patients tested in 1996-1997 were evaluated in detail by comparing 431 individuals with positive patch test reactions with the rest of the group found negative to turpentine. Using the so-called MOAHLFA index, the following characteristics were shown. Turpentine allergy (a) was found to be significantly less frequent in men and in patients with occupational dermatitis, (b) showed no difference in its association with atopic dermatitis, (c) patients with turpentine allergy had significantly less symptoms of the hands, more symptoms of the legs or in the face and (d) were significantly more often aged over 60 years. Also, patients sensitized to turpentine had increased rates of additional sensitizations. The definite reason for the increase in turpentine sensitization in the population tested here is not clear. Therefore, a detailed exposure analysis is necessary; the new increase in turpentine allergies may be due to popular topical remedies or household chemicals.
authors.affiliation: Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Treudler
authors.forename: G
authors.initials: G
authors.lastname: Richter
authors.forename: J
authors.initials: J
authors.lastname: Geier
authors.forename: A
authors.initials: A
authors.lastname: Schnuch
authors.forename: C E
authors.initials: CE
authors.lastname: Orfanos
authors.forename: B
authors.initials: B
authors.lastname: Tebbe
mesh_terms: D000328:Adult; D000367:Age Factors; D000485:Allergens / Q000009:adverse effects; D001317:Austria; D017449:Dermatitis, Allergic Contact / Q000453:epidemiology*; D003876:Dermatitis, Atopic / Q000453:epidemiology; D017453:Dermatitis, Irritant / Q000453:epidemiology; D009783:Dermatitis, Occupational / Q000453:epidemiology; D004781:Environmental Exposure; D005148:Facial Dermatoses / Q000453:epidemiology; D005260:Female; D005858:Germany; D006229:Hand Dermatoses / Q000453:epidemiology; D006801:Humans; D007868:Leg Dermatoses / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D012737:Sex Factors; D012997:Solvents / Q000009:adverse effects*; D014425:Turpentine / Q000009:adverse effects*
chemical_list: D000485:Allergens; D012997:Solvents; D014425:Turpentine