The development of terminal Schwann cells associated with periodontal Ruffini endings in the rat incisor ligament.
The postnatal development of the terminal Schwann cell, an analogue of the lamellar cell in cutaneous sensory receptors, was examined by histochemistry for non-specific cholinesterase and immunohistochemistry for S-100 protein in the periodontal Ruffini endings of the rat incisor. Double immunohistochemistry for S-100 protein and protein gene product 9.5 (PGP 9.5) was also performed to examine the relationship between terminal Schwann cells and axons. Histochemistry for non-specific cholinesterase was able to demonstrate the age-related development of the terminal Schwann cells; the morphology and distribution of the developing terminal Schwann cells became almost identical to those in adults during postnatal days 15-18. Axons showing PGP 9.5-like immunoreactivity elongated and expanded after arrangement of terminal Schwann cells in the alveolus-related part. This suggests that the terminal Schwann cell is important in the development and maturation of the periodontal Ruffini endings.
Hayashi
S
S
Department of Oral Anatomy, Faculty of Dentistry, Niigata University, Niigata, Japan. sachipro@dent.niigata-u.ac.jp
Nakakura-Ohshima
K
K
Ohshima
H
H
Noda
T
T
Honma
S
S
Wakisaka
S
S
Maeda
T
T
D000818:Animals; D001369:Axons / Q000201:enzymology; D002454:Cell Differentiation; D002802:Cholinesterases / Q000378:metabolism; D007180:Incisor; D008465:Mechanoreceptors / Q000166:cytology* / Q000201:enzymology / Q000254:growth & development; D018613:Microscopy, Confocal; D010513:Periodontal Ligament / Q000166:cytology* / Q000254:growth & development / Q000294:innervation; D051381:Rats; D017208:Rats, Wistar; D009418:S100 Proteins / Q000378:metabolism; D012583:Schwann Cells / Q000166:cytology* / Q000201:enzymology; D013869:Thiolester Hydrolases / Q000378:metabolism; D043222:Ubiquitin Thiolesterase
D009418:S100 Proteins; D002802:Cholinesterases; D013869:Thiolester Hydrolases; D043222:Ubiquitin Thiolesterase