title: Hospital-acquired brevundimonas vesicularis septicaemia following open-heart surgery: case report and literature review.
abstract: Brevundimonas vesicularis (B. vesicularis) is a pseudomonad rarely encountered in human infection. A case of nosocomial septicaemia with this organism following open-heart surgery is presented, with a review of the literature. The isolate demonstrated resistance to ciprofloxacin and aztreonam, which has not yet been reported. Treatment with piperacillin/tazobactam resulted in full recovery. A review of the literature reveals that B. vesicularis is a virulent organism involved in serious infections such as central nervous system infection or bacteraemia, some of which are nosocomial. Meanwhile, empiric therapy for B. vesicularis infection should include a broad-spectrum antimicrobial agent until susceptibility results are known.
authors.affiliation: Infectious Disease Institute, Soroka Medical Center and the Ben-Gurion University of the Negev, Beer-Sheva, Israel.
authors.forename: J
authors.initials: J
authors.lastname: Gilad
authors.forename: A
authors.initials: A
authors.lastname: Borer
authors.forename: N
authors.initials: N
authors.lastname: Peled
authors.forename: K
authors.initials: K
authors.lastname: Riesenberg
authors.forename: S
authors.initials: S
authors.lastname: Tager
authors.forename: A
authors.initials: A
authors.lastname: Appelbaum
authors.forename: F
authors.initials: F
authors.lastname: Schlaeffer
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000494:pharmacology; D001398:Aztreonam / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D003428:Cross Infection / Q000382:microbiology*; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D008946:Mitral Valve Stenosis / Q000150:complications* / Q000601:surgery; D008997:Monobactams / Q000494:pharmacology; D011183:Postoperative Complications / Q000382:microbiology*; D011549:Pseudomonas / Q000187:drug effects / Q000302:isolation & purification*; D018805:Sepsis / Q000382:microbiology*
chemical_list: D000890:Anti-Infective Agents; D008997:Monobactams; D002939:Ciprofloxacin; D001398:Aztreonam