[The multifood allergy syndrome].
Multiple food intolerance in infants and young children is increasingly diagnosed. More than 40% of infants less than 1 y.o. could be affected. The syndrome is characterized by the seriousness of atopic dermatitis (SCORAD > 50), by enterocolitis or failure to thrive or various associations of symptoms that may change over time. The evolution is long-lasting. Common food allergens are milk, egg, soy, wheat, but other ones can be implicated. The diagnosis is established by standardized oral challenges. Multiple etiopathogenic factors are involved: atopy, gastro-enteritis induced intestinal hyperpermeability, precocity of food diversification, breast-feeding continued after the onset of symptoms. Amino-acid based formulas have changed the evolution.
Moneret-Vautrin
D A
DA
Service de Médecine Interne, Immunologie Clinique et Allergologie, Hôpital Central, Nancy.
Kanny
G
G
Guérin
L
L
Flabbee
J
J
Lemerdy
P
P
D000485:Allergens / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D003429:Cross Reactions; D003876:Dermatitis, Atopic / Q000209:etiology; D005502:Food / Q000009:adverse effects; D005512:Food Hypersensitivity / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D005759:Gastroenteritis / Q000209:etiology; D006130:Growth Disorders / Q000209:etiology; D006801:Humans; D007223:Infant; D007225:Infant Food / Q000009:adverse effects; D007408:Intestinal Absorption; D013577:Syndrome
D000485:Allergens