[Contribution of immune complex pathological reactions to immunogenesis of pulmonary tuberculosis].
The association of long-term persistence of circulating immune complexes in blood flow with their deposits in the lung in 54.4% of cases and with morphological reactions of cellular and tissue structures, with the functional status of the immune system and with the progression of a tuberculous process, which was found immunohistochemical, immunological, and light microscopic studies in 68 patients with pulmonary tuberculosis, and the high reproducibility of lung-damaging effects of immune complexes in the experiment suggest that the immune complex pathological mechanism is involved into the pathogenesis of progressive pulmonary tuberculosis.
Surkova
L K
LK
Shpakovskaia
N S
NS
Dius'mikeeva
M I
MI
D000293:Adolescent; D000328:Adult; D000818:Animals; D000936:Antigen-Antibody Complex / Q000276:immunology*; D018450:Disease Progression; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D008297:Male; D008875:Middle Aged; D051381:Rats; D013601:T-Lymphocytes / Q000276:immunology; D014397:Tuberculosis, Pulmonary / Q000276:immunology* / Q000473:pathology
D000936:Antigen-Antibody Complex; D007136:Immunoglobulins