title: Statistical approaches for evaluation of genetic risk factor of peripheral arterial occlusive disease.
abstract: In the paper we show results of medical study from statistical point of view. The medical study was aimed to study genetic risk factors of peripheral arterial occlusive diseases in Czech population. Two genes, CBS and MTHFR were examined, as various genotypes of these genes are thought to have impact on amino thiols, who participate in variety of reactions in vasculature. Statistical part of the study was responsible for analysis and interpretation of collected data.
authors.affiliation: European Center for Medical Informatics, Statistics and Epidemiology of Charles University, Prague, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Svatos
authors.forename: M
authors.initials: M
authors.lastname: Orendác
authors.forename: B
authors.initials: B
authors.lastname: Musková
authors.forename: J
authors.initials: J
authors.lastname: Hyánek
authors.forename: V
authors.initials: V
authors.lastname: Kozich
authors.forename: J
authors.initials: J
authors.lastname: Zvárová
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000603:Amino Acids, Sulfur / Q000235:genetics; D001157:Arterial Occlusive Diseases / Q000235:genetics*; D003541:Cystathionine beta-Synthase / Q000235:genetics; D003625:Data Collection; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005838:Genotype; D006801:Humans; D008297:Male; D008432:Mathematical Computing; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D008875:Middle Aged; D008957:Models, Genetic; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000235:genetics; D018570:Risk Assessment
chemical_list: D000603:Amino Acids, Sulfur; D000587:Oxidoreductases Acting on CH-NH Group Donors; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D003541:Cystathionine beta-Synthase