Comparison of equine amnion and a nonadherent wound dressing material for bandaging pinch-grafted wounds in ponies.
OBJECTIVE
To evaluate healing of pinch-grafted wounds on the distal aspect of the limbs of ponies bandaged with equine amnion or a standard nonadherent wound dressing material.


METHODS
6 ponies.


METHODS
A 2.5x2.5-cm full-thickness section of skin was removed from the dorsal aspect of each limb at the midpoint of the metacarpus or metatarsus. Six days later, wounds were grafted with partial-thickness pinch grafts. Half the wounds were bandaged with amnion, and the other half were bandaged with a nonadherent dressing. Bandages were changed every 3 days until wound healing was complete. At each bandage change, numbers of grafts lost were recorded, and wounds were measured.


RESULTS
Percentage of grafts lost from wounds bandaged with amnion was not significantly different from percentage lost from wounds bandaged with the nonadherent dressing. Median healing time for wounds bandaged with amnion (30 days) was significantly less than median healing time for wounds bandaged with the nonadherent dressing (39 days). All wounds were healed by day 45.


CONCLUSIONS
Results suggest that amnion can be used for bandaging pinch-grafted wounds on the distal aspect of the limbs of ponies.
Goodrich
L R
LR
Department of Large Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg 24061, USA.
Moll
H D
HD
Crisman
M V
MV
Lessard
P
P
Bigbie
R B
RB
D000650:Amnion / Q000502:physiology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D005121:Extremities / Q000293:injuries* / Q000601:surgery; D006097:Granulation Tissue / Q000502:physiology; D006736:Horses / Q000601:surgery*; D009779:Occlusive Dressings / Q000009:adverse effects / Q000662:veterinary*; D010653:Phenylbutazone / Q000627:therapeutic use; D016038:Skin Transplantation / Q000379:methods / Q000662:veterinary*; D014945:Wound Healing / Q000502:physiology; D014947:Wounds and Injuries / Q000601:surgery / Q000662:veterinary*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010653:Phenylbutazone