Primary hemifacial spasm and arterial hypertension: a multicenter case-control study.
In a case-control study, the authors found that arterial hypertension occurred more frequently among 115 patients with primary hemifacial spasm than among 115 neurologic controls matched for age (+/-5 years), sex, and referral center. The association was not confounded by education level, smoking history, diabetes, or other diseases (adjusted OR 2.64; 95% CI 1.3 to 5.33, p = 0.007). Hypertension was significantly associated with the outcome in the left-sided group (OR 4.0; 95% CI 1.4 to 11.5), but data concerning patients with right-sided spasm were inconclusive (OR 1.05; 95% CI 0.36 to 3.1). In our sample, hypertension either preceded or followed the onset of hemifacial spasm.
Defazio
G
G
Department of Neurologic and Psychiatric Sciences, University of Bari, Italy.
Berardelli
A
A
Abbruzzese
G
G
Coviello
V
V
De Salvia
R
R
Federico
F
F
Marchese
R
R
Vacca
L
L
Assennato
G
G
Livrea
P
P
D000368:Aged; D016022:Case-Control Studies; D005260:Female; D019569:Hemifacial Spasm / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged