title: Prevention of subdural fluid collections following transcortical intraventricular and/or paraventricular procedures by using fibrin adhesive.
abstract: OBJECTIVE
  Subdural fluid collections following transcortical intraventricular and/or paraventricular neurosurgical procedures for tumors are common and can be difficult to treat. The authors prospectively studied the efficacy of a fibrin adhesive (Tisseel) in closing cortical and ependymal defects following intraventricular and/or paraventricular lesion resection and in preventing the development of subdural fluid collections.
  
  
  METHODS
  Twenty-five patients who underwent 29 transcortical approaches for the resection of intraventricular and/or paraventricular lesions were studied. No patient developed a symptomatic subdural fluid collection and no new seizure or progression of a preexisting seizure disorder was encountered during a median follow-up time of 29 months (range 1-57 months). The incidence of preoperative hydrocephalus was 72% and four (22%) of these patients required postoperative shunt placement.
  
  
  CONCLUSIONS
  The use of a fibrin adhesive to seal cortical and ependymal defects after transcortical procedures appears to prevent the development of subdural fluid collections.
authors.affiliation: Brain Tumor Research Laboratories, Centre for Pediatric Neurosciences, University of Western Ontario, London, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Al-Yamany
authors.forename: R F
authors.initials: RF
authors.lastname: Del Maestro
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002540:Cerebral Cortex / Q000601:surgery; D002551:Cerebral Ventricle Neoplasms / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D003399:Craniotomy; D004805:Ependyma / Q000601:surgery; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D012086:Reoperation; D013353:Subdural Effusion / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D015718:Fibrin Tissue Adhesive