title: Melanocytoma of the left optic nerve head and right retrobulbar optic neuropathy compressed by a tuberculum sellae meningioma.
abstract: A 40-year-old woman had a highly pigmented, slightly elevated tumor on the left optic disc. She had no visual disturbance in the left eye. The tumor was stationary for 5 years. At age 45 years, she complained of decreased visual acuity in the right eye. Magnetic resonance imaging showed a right-shifted homogeneous lesion at the tuberculum sellae. Histopathologic study of the excised lesion revealed interlacing bundles of spindle-shaped fibroblast-like cells with whorl formation. We believe that a relationship between melanocytoma of the optic nerve head and a tuberculum sellae meningioma may exist rather than a chance occurrence, as previously suggested by others.
authors.affiliation: Department of Ophthalmology, Toyama Medical and Pharmaceutical University, Toyama, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Shinoda
authors.forename: S
authors.initials: S
authors.lastname: Hayasaka
authors.forename: Y
authors.initials: Y
authors.lastname: Nagaki
authors.forename: C
authors.initials: C
authors.lastname: Kadoi
authors.forename: M
authors.initials: M
authors.lastname: Kurimoto
authors.forename: E
authors.initials: E
authors.lastname: Okada
mesh_terms: D000328:Adult; D003251:Constriction, Pathologic; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000150:complications* / Q000175:diagnosis; D008579:Meningioma / Q000150:complications* / Q000175:diagnosis; D009508:Nevus, Pigmented / Q000150:complications* / Q000175:diagnosis; D009898:Optic Disk / Q000473:pathology*; D019574:Optic Nerve Neoplasms / Q000150:complications* / Q000175:diagnosis; D009902:Optic Neuritis / Q000150:complications* / Q000175:diagnosis; D012658:Sella Turcica / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed