title: Depletion of head kidney neutrophils and cells with basophilic granules during peritoneal inflammation in the goldfish, Carassius auratus.
abstract: The head kidney morphology of the goldfish with the experimental peritoneal inflammation (on day 2 after i.p. injection with sterile 3% Thioglycollate) is compared with that in the control fish (i.e. on day 2 after i.p. injection with a strile physiological saline PBS) with special emphasis on identification of granulocytes on semithin and consecutive ultrathin sections. The most striking feature of head kidneys of goldfish in the course of peritoneal inflammation is a severe depletion of mature neutrophils and cells with basophilic granules (basophils/mast cells). These observations suggest the involvement of the head kidney, the main hematopoietic organ of teleosts, in the inflammatory process.
authors.affiliation: Institute of Embryology and Histology, University of Vienna, Austria.
authors.forename: E
authors.initials: E
authors.lastname: Bielek
authors.forename: J
authors.initials: J
authors.lastname: Bigaj
authors.forename: M
authors.initials: M
authors.lastname: Chadzińska
authors.forename: B
authors.initials: B
authors.lastname: Płytycz
mesh_terms: D000818:Animals; D001491:Basophils / Q000276:immunology / Q000648:ultrastructure; D004195:Disease Models, Animal; D006054:Goldfish / Q000502:physiology*; D007249:Inflammation; D007674:Kidney Diseases / Q000473:pathology*; D008407:Mast Cells / Q000276:immunology / Q000648:ultrastructure; D008854:Microscopy, Electron; D009504:Neutrophils / Q000276:immunology* / Q000648:ultrastructure; D010529:Peritoneal Cavity