title: Pyrronamycin A and B, novel antitumor antibiotics containing pyrrole-amide repeating unit, produced by Streptomyces sp.
authors.affiliation: Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Machida-shi, Tokyo, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Asai
authors.forename: Y
authors.initials: Y
authors.lastname: Sakai
authors.forename: H
authors.initials: H
authors.lastname: Ogawa
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashita
authors.forename: S
authors.initials: S
authors.lastname: Kakita
authors.forename: K
authors.initials: K
authors.lastname: Ochiai
authors.forename: T
authors.initials: T
authors.lastname: Ashizawa
authors.forename: A
authors.initials: A
authors.lastname: Mihara
authors.forename: T
authors.initials: T
authors.lastname: Mizukami
authors.forename: H
authors.initials: H
authors.lastname: Nakano
mesh_terms: D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification* / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use; D002277:Carcinoma / Q000188:drug therapy*; D004214:Distamycins / Q000627:therapeutic use; D005285:Fermentation; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D051379:Mice; D008819:Mice, Nude; D008826:Microbial Sensitivity Tests; D011758:Pyrroles / Q000302:isolation & purification* / Q000627:therapeutic use*; D012510:Sarcoma 180 / Q000188:drug therapy*; D013302:Streptomyces; D013329:Structure-Activity Relationship
chemical_list: D000903:Antibiotics, Antineoplastic; D000998:Antiviral Agents; D004214:Distamycins; D011758:Pyrroles; C406048:pyrronamycin A; C406049:pyrronamycin B; C030000:stallimycin