title: Warning! Nearby construction can profoundly affect your experiments.
abstract: This is meant to alert people to potentially major effects of construction projects on research results. Because we study the effects of stress on regulation of ACTH and corticosterone secretion and of serotonin receptors and stress on energy balance, we serve as an early warning system when things go awry. Most of our experiments include taking daily, or twice daily, measurements of rat or mouse weights and food intake as well as stress hormone levels. We are highly sensitized to environmental disruption and we've shown previously the effects of construction on stress hormones (1). However, we did not anticipate the change and disruption in energy balance that may occur in response to environmental perturbation. We provide two examples of these, below.
authors.affiliation: Department of Physiology, University of California San Francisco, 94143-0444, USA. dallman@itsa.ucsf.edu
authors.forename: M F
authors.initials: MF
authors.lastname: Dallman
authors.forename: S F
authors.initials: SF
authors.lastname: Akana
authors.forename: M E
authors.initials: ME
authors.lastname: Bell
authors.forename: S
authors.initials: S
authors.lastname: Bhatnagar
authors.forename: S
authors.initials: S
authors.lastname: Choi
authors.forename: A
authors.initials: A
authors.lastname: Chu
authors.forename: F
authors.initials: F
authors.lastname: Gomez
authors.forename: K
authors.initials: K
authors.lastname: Laugero
authors.forename: L
authors.initials: L
authors.lastname: Soriano
authors.forename: V
authors.initials: V
authors.lastname: Viau
mesh_terms: D000818:Animals; D001835:Body Weight; D004435:Eating; D005160:Facility Design and Construction; D051379:Mice; D018345:Mice, Knockout / Q000254:growth & development / Q000502:physiology* / Q000523:psychology; D010641:Phenotype; D013312:Stress, Physiological / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology