title: Tactile stimulation activates dopamine release in the lateral septum.
abstract: Little is known about the functional properties of the dopamine innervation of the lateral septum. In this study, the feasibility of using microdialysis to assess action-potential mediated release of dopamine in the lateral septum was established. A mild stressor, in the form of handling, significantly increased septal dopamine levels, implicating a role for dopamine in sensory-related processing associated with the septal complex.
authors.affiliation: Department of Psychiatry, Yale University School of Medicine, VA Medical Center 116A/2, West Haven, CT 06516, USA.
authors.forename: B W
authors.initials: BW
authors.lastname: Adams
authors.forename: B
authors.initials: B
authors.lastname: Moghaddam
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004298:Dopamine / Q000032:analysis / Q000378:metabolism*; D005110:Extracellular Space / Q000378:metabolism; D005240:Feasibility Studies; D006234:Handling, Psychological; D008297:Male; D017551:Microdialysis; D010812:Physical Stimulation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012686:Septal Nuclei / Q000187:drug effects / Q000378:metabolism*; D013312:Stress, Physiological / Q000378:metabolism; D013779:Tetrodotoxin / Q000494:pharmacology
chemical_list: D013779:Tetrodotoxin; D004298:Dopamine