Mediastinal growing teratoma syndrome.
A 27-year-old man had undergone orchiectomy and chemotherapy for testicular cancer. Despite normalization of raised tumor marker levels after postoperative chemotherapy, computed tomographic scanning demonstrated multiple swellings of the para-aortic lymph nodes with extension from beneath the aortic arch to the bifurcation of the descending aorta. Open biopsies of the para-aortic lymph nodes disclosed mature teraroma without malignant cells. The patient presented the typical features of mediastinal and retroperitoneal growing teratoma syndrome. A two stage resection of the tumors was performed via laparotomy and left thoracotomy. Histological examination of the resected specimens revealed a mature teratoma component without malignant cells. Upon follow-up sixteen months later, the patient was well and without recurrence.
Yoshioka
M
M
First Department of Surgery, Kumamoto University School of Medicine, Japan.
Mori
T
T
Okuma
T
T
Kitamura
N
N
Ito
N
N
Nishi
K
K
D000328:Adult; D005500:Follow-Up Studies; D018237:Germinoma / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology / Q000601:surgery*; D016609:Neoplasms, Second Primary; D009919:Orchiectomy; D012186:Retroperitoneal Neoplasms / Q000473:pathology / Q000601:surgery; D013577:Syndrome; D013724:Teratoma / Q000473:pathology / Q000601:surgery*; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000601:surgery; D016896:Treatment Outcome