title: Is there immunity to Schistosoma japonicum?
abstract: The Oriental schistosome, Schistosoma japonicum, unlike the other two major schistosomes that infect humans (S. mansoni and S. haematobium), is a zoonotic species. The transmission dynamics and the potential effects of host-related regulatory factors, including immunity, are likely to be distinct for this parasite. Here, Allen Ross and collaborators from Australia, China and the Philippines discuss recently published and established epidemiological and laboratory data bearing on anti-infection immunity to Asian schistosomiasis, and contrast these findings with the emerging picture of development of anti-infection immunity against the African schistosomes. Implications for vaccines and other control strategies for schistosomiasis japonica are also discussed.
authors.affiliation: Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research and University of Queensland, Brisbane, Queensland, Australia.
authors.forename: A G
authors.initials: AG
authors.lastname: Ross
authors.forename: A C
authors.initials: AC
authors.lastname: Sleigh
authors.forename: Y S
authors.initials: YS
authors.lastname: Li
authors.forename: G M
authors.initials: GM
authors.lastname: Williams
authors.forename: G D
authors.initials: GD
authors.lastname: Aligui
authors.forename: D P
authors.initials: DP
authors.lastname: McManus
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000818:Animals; D000909:Antibodies, Helminth / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007073:Immunoglobulin E / Q000276:immunology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012549:Schistosoma japonicum / Q000276:immunology*; D012554:Schistosomiasis japonica / Q000453:epidemiology / Q000276:immunology*; D017678:Sex Distribution
chemical_list: D000909:Antibodies, Helminth; D007073:Immunoglobulin E