[Eruptive xanthogranulomatosis in a trisomy 21 patient with acute lymphoblastic leukemia].
BACKGROUND
Juvenile xanthogranulomas may be associated with myeloproliferative disorders, usually juvenile chronic granulocytic leukemia.


METHODS
We report the case of a 25-year-old man with Down's syndrome who presented eruptive xanthogranulomas. At this time, the patient was being treated for acute lymphocytic leukemia. The eruption increased with an extensive unusual "satellite" arrangement despite apparent remission of the acute leukemia. Leukemia relapse occurred some months later.


CONCLUSIONS
This case had an unusual clinical presentation. It also suggests their might be a link between the clinical course of lymphocytic leukemia and juvenile xanthogranuloma.
Sarthou-Bruere
S
S
Clinique Dermatologique, CHU, Place Alexis-Ricordeau, 44093 Nantes Cedex 1.
Milpied-Homsi
B
B
Mahe
B
B
Cassagnau
E
E
Stalder
J F
JF
D000328:Adult; D000367:Age Factors; D004314:Down Syndrome / Q000150:complications*; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000628:therapy; D012074:Remission Induction; D012867:Skin / Q000473:pathology; D014972:Xanthogranuloma, Juvenile / Q000150:complications* / Q000175:diagnosis / Q000473:pathology