title: Congenital laryngeal webs: surgical management and clinical embryology.
abstract: Laryngeal webs are uncommon congenital anomalies. The formation of a laryngeal web represents anomalous embryologic development of the larynx. The extent of airway involvement varies which ultimately affects surgical management. A series of five congenital laryngeal webs each with subglottic involvement is reported. One patient also had a ventral laryngeal cleft. All patients ultimately required open laryngeal reconstruction, either laryngotracheal reconstruction (LTR) or thyrotomy (laryngofissure) and silastic keel, to correct the defect and all were decannulated. Findings at surgery correlate with recent descriptions of embryonic laryngeal development though the actual mechanism by which webs develop remains unknown. The findings suggest that congenital glottic webs require accurate endoscopic diagnosis and open airway reconstruction for definitive treatment.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Oregon Health Sciences University, Doernbecher Children's Hospital, 3147 SW Sam Jackson Park Rd, Portland, OR 97201-3096, USA. milczukh@ohsu.edu
authors.forename: H A
authors.initials: HA
authors.lastname: Milczuk
authors.forename: J D
authors.initials: JD
authors.lastname: Smith
authors.forename: E C
authors.initials: EC
authors.lastname: Everts
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D005931:Glottis / Q000002:abnormalities / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D007828:Laryngoscopy; D007829:Laryngostenosis / Q000151:congenital / Q000601:surgery*; D007830:Larynx / Q000002:abnormalities* / Q000196:embryology* / Q000601:surgery; D008297:Male; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome