title: Urease inhibition: a tool for toxicity identification in sediment elutriates.
abstract: A method for the detection and confirmation of heavy metal toxicants in sediment elutriates based on a urease inhibition assay, ICP-AES analysis and EDTA chelation in the frame of toxicity identification evaluation (TIE) is presented. Zinc was identified as the major toxicant in pHstat elutriates of sediments of the river Saale (Germany). Implications of natural and anthropogenic chelating agents, which are frequently present in environmental samples, on toxicity confirmation of heavy metals based on the toxic unit approach are discussed.
authors.affiliation: Department of Chemical Ecotoxicology, UFZ Centre for Environmental Research, Leipzig, Germany. wb@uoe.ufz.de
authors.forename: W
authors.initials: W
authors.lastname: Brack
authors.forename: A
authors.initials: A
authors.lastname: Paschke
authors.forename: H
authors.initials: H
authors.lastname: Segner
authors.forename: R
authors.initials: R
authors.lastname: Wennrich
authors.forename: G
authors.initials: G
authors.lastname: Schüürmann
mesh_terms: D004784:Environmental Monitoring / Q000379:methods; D019015:Geologic Sediments / Q000737:chemistry; D019216:Metals, Heavy / Q000032:analysis*; D014510:Urease / Q000187:drug effects / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D019216:Metals, Heavy; D014874:Water Pollutants, Chemical; D014510:Urease