[ABC of osteoporosis therapy. Which drugs for prevention and therapy?].
Medical Prevention and Therapy Fractures in the elderly, in particular of the proximal femur, may give rise to functional impairment with loss of independence and mobility. Apart from falls, the most common cause of fractures is osteoporosis or other impairments of mechanical stability of bone. In addition to the avoidance of falls and their sequelae, and the minimization of risk factors where possible, optimization of the mechanical stability of the bone is an important point of attack for interventional strategies. Current data on medical possibilities of osteoporosis prevention and treatment are presented and evidence for their effectiveness in reducing fractures discussed. Recommendations based on confirmed data are made, and possible future therapeutic approaches discussed.
Brückel
J
J
Abteilung Innere Medizin, Universitätsklinikum Ulm. joachim.brueckel@medizin
D000368:Aged; D002118:Calcium / Q000008:administration & dosage; D004164:Diphosphonates / Q000008:administration & dosage; D015914:Estrogen Replacement Therapy; D005260:Female; D005459:Fluorides / Q000008:administration & dosage; D005598:Fractures, Spontaneous / Q000517:prevention & control; D006620:Hip Fractures / Q000517:prevention & control; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000188:drug therapy* / Q000209:etiology; D012307:Risk Factors; D014807:Vitamin D / Q000008:administration & dosage
D004164:Diphosphonates; D014807:Vitamin D; D005459:Fluorides; D002118:Calcium