title: Treatment of pain in trauma patients with injuries of the upper limb.
abstract: Since preoperative pain therapy of a trauma patient did not play an outstanding role in the past, this article shall give information about the adequate treatment of such patients, which can be mainly divided into three phases: the prehospitalisation phase with stabilisation of the trauma patient, the early phase of hospitalisation with further stabilisation, diagnosis and surgery, and finally the postoperative phase with corresponding treatment. An optimal analgesic in the prehospitalisation phase should guarantee good analgesic effects, rapid onset and good controllability, simple handling and the opportunity to combine it with other medication. In addition, it should prevent a wide therapeutic range and the absence of side effects. Opioids and ketamine are available for acute pain therapy after trauma. The main opioids used are piritramide and pethidine, with piritramide acting as a sedative at the same time and with pethidine preventing the stronger analgesic effect. The intravenous use of ketamine has become established in trauma patients because of its excellent analgesia at subanaesthetic doses. Especially in multiple trauma patients, the indication for general anaesthesia with intubation should be established on a liberal basis. Nevertheless, for some patterns of injury regional techniques may be advantageous; therefore, this article describes the possible regional procedures (such as intravenous regional anaesthesia or block of peripheral nerves). Concerning the postoperative phase, an individual pain management can be guaranteed by systemic pharmacotherapy and regional catheter techniques, for example the brachial plexus blockade that results in a long period of free pain.
authors.affiliation: Department of Anaesthesiology and Intensive-Care Medicine, St Franziskus Hospital Münster, Hohenzollernring 72, D-48145, Münster, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Möllmann
authors.forename: U
authors.initials: U
authors.lastname: Auf der Landwehr
mesh_terms: D000701:Analgesics, Opioid / Q000627:therapeutic use; D000765:Anesthesia, Conduction / Q000379:methods*; D001134:Arm Injuries / Q000601:surgery*; D000075202:Contraindications; D006801:Humans; D007649:Ketamine / Q000627:therapeutic use; D008614:Meperidine / Q000627:therapeutic use; D009407:Nerve Block / Q000009:adverse effects / Q000379:methods; D010149:Postoperative Pain / Q000188:drug therapy*; D010892:Pirinitramide / Q000627:therapeutic use; D011300:Preoperative Care / Q000379:methods
chemical_list: D000701:Analgesics, Opioid; D010892:Pirinitramide; D007649:Ketamine; D008614:Meperidine