title: Flow-injection spectrophotometric methods for the determination of tenoxicam.
abstract: Two sensitive and rapid flow-injection spectrophotometric methods are proposed for the determination of tenoxicam (TX). In the first method, a Fe(III)-tenoxicam complex is formed in a methanolic medium and the absorbance is measured at 540 nm, while the second method involves measurement of the absorbance at 355 nm of a solution containing the drug in hydrochloric acid medium. In both methods, the peak heights were proportional to tenoxicam concentration over the ranges 7.0-320 and 0.5-8.5 mg/l(-1), respectively. The methods have been applied to the routine determination of the drug in dosage forms.
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Spain.
authors.forename: M S
authors.initials: MS
authors.lastname: García
authors.forename: C
authors.initials: C
authors.lastname: Sánchez-Pedreño
authors.forename: M I
authors.initials: MI
authors.lastname: Albero
authors.forename: M J
authors.initials: MJ
authors.lastname: Gimenez
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000032:analysis*; D017022:Flow Injection Analysis; D004364:Pharmaceutical Preparations / Q000032:analysis; D010894:Piroxicam / Q000031:analogs & derivatives* / Q000032:analysis; D013053:Spectrophotometry / Q000379:methods
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004364:Pharmaceutical Preparations; D010894:Piroxicam; C032801:tenoxicam