title: [Current topics of acute encephalitis and encephalopathy: introductory remarks].
abstract: Encephalitis/encephalopathy is a neurological syndrome characterized by acute onset, symptoms of intracranial hypertension accompanying severe sequels or death. Encephalitis is caused by microbial infection of central nervous system, such as neurotrophic or conventional viruses. Infectious encephalopathy shows similar clinical symptoms to acute encephalitis, without any evidence of inflammation and microbial infection in brain tissues. The national epidemiological surveillance of the diseases is carried out to study the frequency and prognosis of patients with both diseases. The principal treatment is quite different in the both, in the former the eradication of microbial from the brain and in the latter the reduction of pressure of brain edema. Furthermore, the improvement of the brain with severe destruction requires such new step to reduce the activities of enzymes or cytokines to destroy brain tissues, as a mild hypothermia to lower body and brain temperature to 33-34 degrees C.
authors.affiliation: Department of Pediatrics, Teikyo University School of Medicine, Tokyo.
authors.forename: T
authors.initials: T
authors.lastname: Abe
authors.forename: N
authors.initials: N
authors.lastname: Okabe
mesh_terms: D000208:Acute Disease; D003937:Diagnosis, Differential; D004660:Encephalitis / Q000209:etiology / Q000628:therapy; D006801:Humans; D007036:Hypothermia, Induced; D014777:Virus Diseases