title: [Clinical symptoms of and diagnostic possibilities for hypophyseal adenoma in horses].
abstract: Hirsutism was the most often observed symptom in horses with a pituitary gland tumor and was present in all 13 examined horses. Other symptoms were atrophy of muscles (n = 10), hyperhidrosis (n = 8), polyuria/polydipsia (n = 5), bulging or supraorbital fat (n = 3), polyphagia (n = 2), apathy (n = 2) and seizures (n = 2). Laminitis was the most frequently observed concurrent disease (n = 8). Hyperglycaemia (mean, 9.9 +/- 3.71 mmol/l) in 13 horses and glucosuria (median, 55 [range, 2-55] mmol/l) in 7 horses were the most important laboratory results. The dexamethasone suppression test was positive in all tested horses (n = 9) 20 h after administration of dexamethasone. The pituitary gland tumor was visible in every case underwent computed tomography (n = 7). From these results it can be concluded that a pituitary gland tumor can be suspected based on typical clinical signs. Hyperglycaemia and glucosuria support the preliminary diagnosis and a positive dexamethasone suppression test allows a final diagnosis.
authors.affiliation: Klinik für Wiederkäuer- und Pferdemedizin, Universität Zürich.
authors.forename: K
authors.initials: K
authors.lastname: Feige
authors.forename: M W
authors.initials: MW
authors.lastname: Eser
authors.forename: U
authors.initials: U
authors.lastname: Geissbühler
authors.forename: E
authors.initials: E
authors.lastname: Balestra
authors.forename: K
authors.initials: K
authors.lastname: Metzler
mesh_terms: D000236:Adenoma / Q000175:diagnosis / Q000662:veterinary*; D000818:Animals; D005260:Female; D006628:Hirsutism / Q000662:veterinary; D006734:Horse Diseases / Q000175:diagnosis*; D006736:Horses; D006945:Hyperhidrosis / Q000662:veterinary; D008297:Male; D009133:Muscular Atrophy / Q000662:veterinary; D010911:Pituitary Neoplasms / Q000175:diagnosis / Q000662:veterinary*; D014057:Tomography, X-Ray Computed / Q000662:veterinary