title: Benign childhood epilepsy with centrotemporal spikes: is it always benign?
abstract: Most children with benign childhood epilepsy with centrotemporal spikes have few seizures, and some have only one. We describe two children with interictal and ictal findings consistent with this epileptic syndrome but with severe intractable seizures and cognitive decline that resulted in consideration for epilepsy surgery. Spontaneous remission occured in one child; the other is still young. Despite the high seizure burden and cognitive decline, surgical consideration should be withheld, as these seizures are likely to remit.
authors.affiliation: Department of Neurology, The Cleveland Clinic Foundation, OH 44195, USA.
authors.forename: H T
authors.initials: HT
authors.lastname: Ong
authors.forename: E
authors.initials: E
authors.lastname: Wyllie
mesh_terms: D001921:Brain / Q000503:physiopathology; D002675:Child, Preschool; D004569:Electroencephalography; D019305:Epilepsy, Rolandic / Q000503:physiopathology*; D005260:Female; D006801:Humans