The normal female and the male breast epithelium does not express prostate-specific antigen. Preliminary immunohistochemical observations of autopsy breast tissues.
In the normal female and male breast epithelial structures any prostate-specific antigen (PSA) immunohistochemical positivity was observed. Variable PSA expression, which often borders the positivity, was observed in membranes of adipocytes of fat tissue and in the endothelium of small vessels in a female and a male breast. Based on these initial observations, tissue of the normal breast, male or female, can not be considered to be the principal source of PSA.
Zaviacic
M
M
Department of Pathology, Comenius University, School of Medicine and Faculty Hospital, Bratislava, Slovak Republic. zaviacic@fmed.uniba.sk
Ablin
R J
RJ
Ruzicková
M
M
Stvrtina
S
S
Danihel
L
L
Zaviacic
T
T
Pohlodek
K
K
Holomán
K
K
D000328:Adult; D001940:Breast / Q000276:immunology*; D004848:Epithelium / Q000276:immunology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000378:metabolism*; D012016:Reference Values; D012727:Sex Characteristics
D017430:Prostate-Specific Antigen