title: Digested fiber from wheat bran induces cdk inhibitors which block colon epithelial cells in G1.
authors.affiliation: Department of Pathology, State University of New York Health Science Center at Syracuse 13210, USA.
authors.forename: E A
authors.initials: EA
authors.lastname: Friedman
authors.forename: J
authors.initials: J
authors.lastname: Wang
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins; D002455:Cell Division / Q000187:drug effects; D003106:Colon / Q000166:cytology / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D050759:Cyclin-Dependent Kinase Inhibitor p21; D050760:Cyclin-Dependent Kinase Inhibitor p27; D018844:Cyclin-Dependent Kinases / Q000037:antagonists & inhibitors*; D016213:Cyclins / Q000096:biosynthesis*; D004043:Dietary Fiber / Q000378:metabolism / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000378:metabolism; D005227:Fatty Acids / Q000378:metabolism / Q000494:pharmacology; D016193:G1 Phase / Q000187:drug effects*; D006801:Humans; D007413:Intestinal Mucosa / Q000166:cytology / Q000187:drug effects* / Q000201:enzymology; D008869:Microtubule-Associated Proteins / Q000096:biosynthesis; D014908:Triticum; D025521:Tumor Suppressor Proteins
chemical_list: C493956:CDKN1A protein, human; D018797:Cell Cycle Proteins; D050759:Cyclin-Dependent Kinase Inhibitor p21; D016213:Cyclins; D004043:Dietary Fiber; D004791:Enzyme Inhibitors; D005227:Fatty Acids; D008869:Microtubule-Associated Proteins; D025521:Tumor Suppressor Proteins; D050760:Cyclin-Dependent Kinase Inhibitor p27; D018844:Cyclin-Dependent Kinases