title: New DRB1* alleles (HLA-DRB1*1135, DRB1*1430 and DRB1*1433) and a confirmatory sequence (DRB1*1133).
abstract: Three new DRB1 alleles (DRB1*1135, DRB1*1430 and DRB1*1433) and a confirmatory sequence (DRB1*1133) have been identified after following up unusual or novel polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) patterns during routine typing of the DRB1*03,*08,*11,*12,*13 and *14 allele groups. Of the new alleles found and described in this paper, two alleles were initially detected by the PCR-RFLP method which produced unexpected restriction polymorphism (DRB1*1133 and DRB1*1135) while the remaining two were found after following up rare allele typings from this technique (DRB1*1430 and DRB1*1433).
authors.affiliation: Tissue Typing, Australian Red Cross Blood Service-NSW Division, Sydney, Australia. jtrejaut@arcbs.redcross.org.au
authors.forename: J
authors.initials: J
authors.lastname: Tréjaut
authors.forename: D
authors.initials: D
authors.lastname: Hobart
authors.forename: A
authors.initials: A
authors.lastname: Kennedy
authors.forename: W D
authors.initials: WD
authors.lastname: Greville
authors.forename: A
authors.initials: A
authors.lastname: Taverniti
authors.forename: H
authors.initials: H
authors.lastname: Dunckley
mesh_terms: D000483:Alleles; D001483:Base Sequence; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006650:Histocompatibility Testing; D006801:Humans; D008969:Molecular Sequence Data; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid
chemical_list: D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains