Sinonasal lymphomas. Case report.
In the field of Otorhinolaryngology sinonasal lymphomas are relatively uncommon and represent less than 1% of all head and neck malignancies. Nowadays, they are regarded as consisting of two distinct subgroups, characterised by phenotype, location, prognosis and treatment. Lymphomas of the B-Cell phenotype are the most frequent type found in the paranasal sinuses. They are less aggressive and carry a relatively better prognosis. T/NK-Cell lymphomas are mostly found in the nasal cavity. They are more aggressive and carry a relatively worse prognosis. We present a case of a 65-year-old patient, who complained with unilateral right-sided nasal obstruction associated with a sensation of right aural fullness. CT scan demonstrated opacity of the posterior ethmoid and sphenoid sinuses on the right side, with evidence of erosion of the anterior wall of the sphenoid. Nasal endoscopy revealed a smooth purple mass, arising from the right superior meatus, which bled on contact, and which was subsequently shown to be, on histological assessment, a malignant high grade lymphoma, non-Hodgkin's B-cell phenotype. Following a discussion of the case we will present a review of these tumours, which have a poor overall prognosis, focusing on epidemiology, sites of origin, symptoms, investigation and management.
Van Prooyen Keyzer
S
S
ORL & HNS Department, Université Catholique de Louvain, Cliniques Universitaires UCL de Mont-Godinne, Yvoir, Belgium.
Eloy
P
P
Delos
M
M
Doyen
C
C
Bertrand
B
B
Rombaux
P
P
D000368:Aged; D005005:Ethmoid Sinus / Q000473:pathology*; D017809:Fatal Outcome; D034381:Hearing Loss / Q000175:diagnosis; D006801:Humans; D007694:Killer Cells, Natural / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000175:diagnosis*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis*; D016399:Lymphoma, T-Cell / Q000175:diagnosis; D008297:Male; D015508:Nasal Obstruction / Q000175:diagnosis; D009298:Nasal Polyps / Q000175:diagnosis*; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis*; D010641:Phenotype; D011379:Prognosis; D013101:Sphenoid Sinus / Q000473:pathology*; D014057:Tomography, X-Ray Computed