title: [Thymus changes in chronic heliotrine-induced hepatitis].
abstract: The structural and morphometrical characteristics of thymus were studied in the dynamics of experimental heliotrine hepatitis. The decrease of areas and cell hypoplasia of cortical zone of the thymus were noted. The destructive processes of the thymocytes were intensified and, in response to it, thymic macrophages activity was enhanced. The facts obtained indicated that the use of the thymic peptides is necessary for correction of immune disorders in chronic hepatitis.
authors.affiliation: Department of Histology, 2nd Medical Institute of Tashkent.
authors.forename: M
authors.initials: M
authors.lastname: Abdurakhmanov
authors.forename: K R
authors.initials: KR
authors.lastname: Tukhtaev
mesh_terms: D000818:Animals; D056487:Chemical and Drug Induced Liver Injury, Chronic / Q000209:etiology / Q000473:pathology*; D008297:Male; D008854:Microscopy, Electron; D011763:Pyrrolizidine Alkaloids / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000187:drug effects / Q000473:pathology*; D013997:Time Factors
chemical_list: D011763:Pyrrolizidine Alkaloids; C010178:heliotrine