title: The endocrine spectrum of arachnoid cysts in childhood.
abstract: BACKGROUND
  On clinical grounds, arachnoid cysts are usually associated with neurological dysfunction. There is little information concerning their involvement in endocrinological disorders.
  
  
  METHODS
  The experience in 6 children (birth to 12 years) with hypothalamic-pituitary disturbances secondary to the presence of intracranial arachnoid cysts is reported and the literature is reviewed.
  
  
  RESULTS
  Three of our children were diagnosed with isolated hormone abnormalities (2 children with precocious puberty and 1 child with growth hormone, GH deficiency). One child presented the unusual combination of GH deficiency and precocious puberty. The remaining 2 children developed panhypopituitarism associated with diabetes insipidus.
  
  
  CONCLUSIONS
  Arachnoid cysts may cause a wide spectrum of endocrinological disorders. Periodical and complete follow-up of every patient is recommended.
authors.affiliation: Division of Pediatric Endocrinology, Children's Hospital, University of Erlangen-Nürnberg, Erlangen, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Mohn
authors.forename: E
authors.initials: E
authors.lastname: Schoof
authors.forename: R
authors.initials: R
authors.lastname: Fahlbusch
authors.forename: D
authors.initials: D
authors.lastname: Wenzel
authors.forename: H G
authors.initials: HG
authors.lastname: Dörr
mesh_terms: D016080:Arachnoid Cysts / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D002648:Child; D004700:Endocrine System Diseases / Q000150:complications* / Q000503:physiopathology; D005260:Female; D019382:Human Growth Hormone / Q000172:deficiency; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology*; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D010913:Pituitary-Adrenal System / Q000503:physiopathology*; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000503:physiopathology; D013963:Thyroid Hormones / Q000097:blood / Q000652:urine; D014057:Tomography, X-Ray Computed
chemical_list: D013963:Thyroid Hormones; D019382:Human Growth Hormone