title: [Optimal dose of indocyanine-green injected from the peripheral vein in cardiac output measurement by pulse dye-densitometry].
abstract: Cardiac output is measured by pulse dye-densitometry using indocyanine-green (ICG). This cardiac output is estimated by correlating with the cardiac output measured by pulmonary artery catheter using thermodilution method. Twenty-four patients scheduled for elective cardiovascular surgeries under general anesthesia were studied. The pulse dye-densitometry monitoring system used was DDG-2001 (Nihon Kohden, Japan). In group A (13 patients: 19 times), ICG was administered from the peripheral vein as bolus doses of 5, 10 or 20 mg (5 mg.ml-1 water solution). In group B (11 patients: 12 times), ICG was administered from the peripheral vein as bolus doses of 20, 10 or 5 mg (5 mg.ml-1 water solution). The correlation (Pearson's correlation coefficient) and precision (the method proposed by Bland and Altman) compared with cardiac output measured by pulmonary artery catheter were examined. Better correlation and precision were recognized after 20 mg ICG injection than 5 or 10 mg ICG injection. In conclusion, the measurement of cardiac output by pulse dye-densitometry with peripheral vein ICG injection was useful using a bolus dose of ICG 20 mg.
authors.affiliation: Department of Anesthesiology, Nara Medical University, Kashihara.
authors.forename: K
authors.initials: K
authors.lastname: Sha
authors.forename: M
authors.initials: M
authors.lastname: Shimokawa
authors.forename: M
authors.initials: M
authors.lastname: Morii
authors.forename: K
authors.initials: K
authors.lastname: Kikumoto
authors.forename: S
authors.initials: S
authors.lastname: Inoue
authors.forename: K
authors.initials: K
authors.lastname: Kishi
authors.forename: K
authors.initials: K
authors.lastname: Kitaguchi
authors.forename: H
authors.initials: H
authors.lastname: Furuya
mesh_terms: D000368:Aged; D002302:Cardiac Output; D004396:Coloring Agents / Q000008:administration & dosage; D003720:Densitometry / Q000379:methods; D005260:Female; D006331:Heart Diseases / Q000503:physiopathology; D006334:Heart Function Tests / Q000379:methods*; D006801:Humans; D007208:Indocyanine Green / Q000008:administration & dosage; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D015203:Reproducibility of Results
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green