Simulated microgravity impairs vascular contractility: role of nitric oxide-dependent vasodilator mechanisms.
Sangha
D S
DS
Department of Pharmacology, College of Medicine, University of California-Irvine 92697-4625, USA.
Vaziri
N D
ND
Ding
Y
Y
Han
S
S
Alem
N
N
Chen
Y A
YA
Purdy
R E
RE
D000818:Animals; D001158:Arteries / Q000187:drug effects / Q000502:physiology; D004730:Endothelium, Vascular / Q000502:physiology; D019417:Hindlimb Suspension / Q000009:adverse effects / Q000502:physiology; D009119:Muscle Contraction / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000502:physiology*; D009569:Nitric Oxide / Q000502:physiology*; D019001:Nitric Oxide Synthase / Q000096:biosynthesis / Q000378:metabolism; D052250:Nitric Oxide Synthase Type III; D009638:Norepinephrine / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D015854:Up-Regulation / Q000502:physiology; D014662:Vasoconstrictor Agents / Q000494:pharmacology; D014664:Vasodilation / Q000187:drug effects / Q000502:physiology*; D018474:Weightlessness Simulation / Q000009:adverse effects*
D014662:Vasoconstrictor Agents; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D052250:Nitric Oxide Synthase Type III; C496316:Nos3 protein, rat; D009638:Norepinephrine