A decision support system for cholinesterase genotyping.
Cholinesterase is a naturally occurring enzyme in the human body. Its importance became apparent when it was recognised that patients undergoing surgery and carrying abnormal genes for this enzyme were unable to recover from a dose of muscle-relaxant. It is therefore important to know the Genotype (the pair of genes) of a patient who might undergo surgery. The computer programme takes laboratory measurements and applies mathematical techniques and clinical judgements to determine the two genes present.
Richards
B
B
Dept of Medical Informatics, UMIST, Manchester, England.
Cadman
J
J
France
M
M
D000110:Acetylcholinesterase / Q000235:genetics*; D019992:Databases as Topic; D003661:Decision Support Techniques; D005838:Genotype; D006801:Humans; D008957:Models, Genetic; D012984:Software
D000110:Acetylcholinesterase