Identification of a novel single nucleotide polymorphism (SNP) in the human organic cation transporter-like 2-antisense (ORCTL2S) gene.
We found a single nucleotide polymorphism (SNP) in exon 3 of the human organic cation transporter-like 2-antisense (ORCTL2S) gene: a base substitution A266G which was confirmed by direct sequencing. Heterozygosity of the polymorphic alleles was 0.45 in a Japanese population. This polymorphism will be useful in the allelic expression analysis of the ORCTL2S gene.
Higashimoto
K
K
Department of Biochemistry, Saga Medical School, Japan.
Soejima
H
H
Katsuki
T
T
Mukai
T
T
D002352:Carrier Proteins / Q000235:genetics*; D002880:Chromosomes, Human, Pair 11; D016373:DNA, Antisense; D005091:Exons; D005787:Gene Frequency; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008565:Membrane Proteins / Q000235:genetics*; D020125:Mutation, Missense; D027701:Organic Cation Transport Proteins; D020641:Polymorphism, Single Nucleotide
D002352:Carrier Proteins; D016373:DNA, Antisense; D008565:Membrane Proteins; D027701:Organic Cation Transport Proteins; C111653:SLC22A18 protein, human; C406488:SLC22A18AS protein, human