title: Expression patterns of two new members of the Semaphorin family in Drosophila suggest early functions during embryogenesis.
abstract: We report the sequence and expression analysis of two new Drosophila members of the Semaphorin family. Both proteins show the presence of Semaphorin domains and transmembrane domains. Both genes are expressed maternally and in embryos, and reveal distinct expression patterns much earlier than the onset of neurogenesis. We also present an overview of the domain structure of all so far known semaphorins in Drosophila. Furthermore, we compared all Drosophila and C. elegans Semaphorins and discuss them in the light of their evolution.
authors.affiliation: Department of Cell & Molecular Biology, Box 94, Lund University, S-22100, Lund, Sweden.
authors.forename: N
authors.initials: N
authors.lastname: Khare
authors.forename: N
authors.initials: N
authors.lastname: Fascetti
authors.forename: S
authors.initials: S
authors.lastname: DaRocha
authors.forename: R
authors.initials: R
authors.lastname: Chiquet-Ehrismann
authors.forename: S
authors.initials: S
authors.lastname: Baumgartner
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015816:Cell Adhesion Molecules, Neuronal / Q000235:genetics*; D003001:Cloning, Molecular; D018076:DNA, Complementary; D004330:Drosophila / Q000196:embryology* / Q000235:genetics; D029721:Drosophila Proteins; D019143:Evolution, Molecular; D015870:Gene Expression; D008562:Membrane Glycoproteins / Q000235:genetics* / Q000378:metabolism / Q000502:physiology; D008969:Molecular Sequence Data; D012333:RNA, Messenger; D039961:Semaphorins; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
chemical_list: D015816:Cell Adhesion Molecules, Neuronal; D018076:DNA, Complementary; D029721:Drosophila Proteins; D008562:Membrane Glycoproteins; D012333:RNA, Messenger; C498727:Sema5c protein, Drosophila; D039961:Semaphorins