[Risk of serious acute asthma due to lupine flour associated with peanut allergy].
Lupine flour (lupinus albus), recently authorized in France in human food, cross-reacts with peanuts. We report a case of acute asthma in a patient with allergy to peanuts.


METHODS
This patient has a severe allergy to peanuts, presenting as acute asthma. Skin prick-tests to raw and cooked lupine flour were positive. The level of specific-IgE (Allerbio, France) to lupine flour were high. Oral challenge test induced acute asthma at a dose of 965 mg of lupine flour. This quantity may be included in 100 g of bread.


CONCLUSIONS
This case report points out the fact that lupine flour is a high-risk allergen in patients presenting allergy to peanuts. It is necessary to evaluate the allergenic risk of new foods before their introduction into human daily food intake and to establish a network of allergy vigilance.
Kanny
G
G
Service de médecine interne, immunologie clinique et allergologie, hôpital Central, CHU, Nancy, France.
Guérin
L
L
Moneret-Vautrin
D A
DA
D000293:Adolescent; D010367:Arachis / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced* / Q000276:immunology; D007887:Fabaceae / Q000009:adverse effects* / Q000276:immunology; D005260:Female; D005433:Flour / Q000009:adverse effects*; D005512:Food Hypersensitivity / Q000150:complications* / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D010946:Plants, Medicinal; D012882:Skin Tests
D007073:Immunoglobulin E