Haematocin, a new antifungal diketopiperazine produced by Nectria haematococca Berk. et Br. (880701a-1) causing nectria blight disease on ornamental plants.
A new antifungal diketopiperazine named haematocin was isolated from the culture broth of Nectria haematococca Berk. et Br. (880701a-1) causing blight disease on ornamental plants, Phalaenopsis spp. and Doritanopsis spp. Its structure was established by spectroscopic methods. Haematocin inhibited the germ-tube elongation and spore-germination of Pyricularia oryzae at the ED50 values of 30 microg/ml and 160 microg/ml, respectively.
Suzuki
Y
Y
The Institute of Physical and Chemical Research (RIKEN), Wako-shi, Saitama, Japan.
Takahashi
H
H
Esumi
Y
Y
Arie
T
T
Morita
T
T
Koshino
H
H
Uzawa
J
J
Uramoto
M
M
Yamaguchi
I
I
D000900:Anti-Bacterial Agents / Q000737:chemistry; D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D007211:Indoles / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D010082:Oxepins / Q000737:chemistry; D010879:Piperazines / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014675:Vegetables / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D007211:Indoles; D010082:Oxepins; D010879:Piperazines; C406046:haematocin; C006370:acetylaranotin