Pyrronamycin A and B, novel antitumor antibiotics containing pyrrole-amide repeating unit, produced by Streptomyces sp.
Asai
A
A
Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Machida-shi, Tokyo, Japan.
Sakai
Y
Y
Ogawa
H
H
Yamashita
Y
Y
Kakita
S
S
Ochiai
K
K
Ashizawa
T
T
Mihara
A
A
Mizukami
T
T
Nakano
H
H
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification* / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use; D002277:Carcinoma / Q000188:drug therapy*; D004214:Distamycins / Q000627:therapeutic use; D005285:Fermentation; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D051379:Mice; D008819:Mice, Nude; D008826:Microbial Sensitivity Tests; D011758:Pyrroles / Q000302:isolation & purification* / Q000627:therapeutic use*; D012510:Sarcoma 180 / Q000188:drug therapy*; D013302:Streptomyces; D013329:Structure-Activity Relationship
D000903:Antibiotics, Antineoplastic; D000998:Antiviral Agents; D004214:Distamycins; D011758:Pyrroles; C406048:pyrronamycin A; C406049:pyrronamycin B; C030000:stallimycin