title: Comparison of acquired cystic kidney disease between hemodialysis and continuous ambulatory peritoneal dialysis.
abstract: OBJECTIVE
  ACKD has been described mainly in patients treated with hemodialysis(HD), and there are only a few reports about the prevalence of ACKD in continuous ambulatory peritoneal dialysis (CAPD) patients. Therefore, we compared the prevalence of ACKD in patients receiving HD and CAPD, and evaluated the possible factors which may affect the development of ACKD.
  
  
  METHODS
  Forty nine HD and 49 CAPD patients who had received dialysis therapy for at least 12 months were enrolled in this cross-sectional study. Patients who had a past history of polycystic kidney disease and had acquired cystic kidney disease on predialysis sonographic exam were excluded. Detection of ACKD was made by ultrasonography and ACKD was defined as 3 or more cysts in each kidney.
  
  
  RESULTS
  The prevalence of ACKD was about 31% (30/98) and there was no significant difference between HD and CAPD patients(27% vs. 34%, p > 0.05). The prevalence of ACKD was not associated with age, sex, primary renal disease, the levels of hemoglobin, BUN, and serum creatinine. However, the duration of dialysis was significantly related to the development of ACKD (presence of ACKD, 74.4 +/- 42.4 months vs. absence of ACKD, 37.8 +/- 24.1 months, p < 0.05).
  
  
  CONCLUSIONS
  The prevalence of ACKD is not different according to the mode of dialysis, and the major determinant of acquired cyst formation is duration of dialysis.
authors.affiliation: Department of Internal Medicine, Catholic University of Korea, Seoul, Korea.
authors.forename: J H
authors.initials: JH
authors.lastname: Park
authors.forename: Y O
authors.initials: YO
authors.lastname: Kim
authors.forename: J H
authors.initials: JH
authors.lastname: Park
authors.forename: B S
authors.initials: BS
authors.lastname: Kim
authors.forename: S A
authors.initials: SA
authors.lastname: Yoon
authors.forename: C W
authors.initials: CW
authors.lastname: Yang
authors.forename: Y S
authors.initials: YS
authors.lastname: Kim
authors.forename: C H
authors.initials: CH
authors.lastname: Han
authors.forename: B S
authors.initials: BS
authors.lastname: Kim
authors.forename: B K
authors.initials: BK
authors.lastname: Bang
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D016009:Chi-Square Distribution; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000453:epidemiology* / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000628:therapy; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects* / Q000379:methods; D015995:Prevalence; D006435:Renal Dialysis / Q000009:adverse effects* / Q000379:methods; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D018709:Statistics, Nonparametric