title: Perinatal differential diagnosis of cystic kidney disease and urinary tract obstruction: anatomic pathologic, ultrasonographic and genetic findings.
abstract: According to the classification of Osathanondh and Potter of cystic kidney diseases an antenatal differential diagnosis is presented, which is based on the anatomic pathologic, ultrasonographic and genetic findings. Since the ultrasound evaluation influences the obstetric and neonatal management, each second and third trimester sonography should consider the most common malformations in pediatric autopsies. The autosomal recessive polycystic kidney disease (ARPK), autosomal dominant polycystic kidney disease (ADPK), multicystic renal dysplasia, obstructive multicystic kidneys and cystic renal malformations found in other syndromes with genetic linkage are discussed in this review.
authors.affiliation: Department of Obstetrics, Womens Hospital/Frauenklinik, Charité Campus Virchow-Klinikum, 13353, Berlin, Germany. jwdud@ukrv.de
authors.forename: W
authors.initials: W
authors.lastname: Friedmann
authors.forename: M
authors.initials: M
authors.lastname: Vogel
authors.forename: J S
authors.initials: JS
authors.lastname: Dimer
authors.forename: A
authors.initials: A
authors.lastname: Luttkus
authors.forename: U
authors.initials: U
authors.lastname: Büscher
authors.forename: J W
authors.initials: JW
authors.lastname: Dudenhausen
mesh_terms: D003937:Diagnosis, Differential; D008040:Genetic Linkage; D006801:Humans; D007690:Polycystic Kidney Diseases / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D016891:Polycystic Kidney, Autosomal Dominant / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D017044:Polycystic Kidney, Autosomal Recessive / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D011296:Prenatal Diagnosis; D016216:Ultrasonography, Prenatal