title: [Design of human liposomal recombinant alpha2-interferon-containing preparation].
abstract: The composition of liposomal lipid phase preparation was selected. The optimum ratio of liposomal lipid phase components was found to produce a a human liposomal recombinant alpha 2-interferon-containing preparation by extrusion across the polycarbonate membranes. The study gave rise to a lyophilized sterile liposomal recombinant alpha 2-interferon preparation. The agent was shown to be stable and retains its antiviral activity within a year.
authors.forename: V V
authors.initials: VV
authors.lastname: Zolin
authors.forename: A A
authors.initials: AA
authors.lastname: Kolokol'tsov
authors.forename: O A
authors.initials: OA
authors.lastname: Agafonova
authors.forename: T G
authors.initials: TG
authors.lastname: Bochkova
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D004337:Drug Carriers; D015195:Drug Design; D015507:Drugs, Investigational; D006801:Humans; D007370:Interferon Type I / Q000494:pharmacology*; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D007372:Interferons; D008081:Liposomes; D011994:Recombinant Proteins; D014777:Virus Diseases / Q000188:drug therapy
chemical_list: D000276:Adjuvants, Immunologic; D004337:Drug Carriers; D015507:Drugs, Investigational; D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D008081:Liposomes; D011994:Recombinant Proteins; D007372:Interferons