title: [Neurosurgical multicenter study of cerebral metastases (Neurosurgical departments of Paris Beaujon, Paris Sainte-Anne, Strasbourg)].
abstract: We report a multicentric outcome study of cerebral metastases in 174 patients collected consecutively in three neurosurgical centers in France. Age and condition of patients allowed surgical operation; the sex ratio was 1.67. The revelation mode was usual. However tumoral hemorrhage frequency was 3.4%. Primitive cancers were usual cancers as in oncological series with a higher proportion of radioresistant metastases. Mean dimension was 30 mm with mean of 1. 25 metastases per patient. Supratentorial localization was more frequent and the metastasis revealed cancer in 40% of cases. Global median survival was 12.1 months. Factors correlated with the survival in our series of patients with cerebral metastases were: solitary cerebral metastasis, extracerebral extension of cancer, treatment of primitive cancer, complete excision and post operative cerebral radiotherapy.
authors.affiliation: Services de Neurochirurgie, Centre Hospitalier Sainte-Anne, 75674 Paris Cedex 14, France.
authors.forename: F
authors.initials: F
authors.lastname: Nataf
authors.forename: E
authors.initials: E
authors.lastname: Emery
authors.forename: P
authors.initials: P
authors.lastname: Kherli
authors.forename: E
authors.initials: E
authors.lastname: Seigneuret
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D002277:Carcinoma / Q000401:mortality / Q000556:secondary / Q000601:surgery; D002543:Cerebral Hemorrhage / Q000209:etiology; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D015993:Life Tables; D008297:Male; D008545:Melanoma / Q000401:mortality / Q000556:secondary / Q000601:surgery; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local; D016017:Odds Ratio; D012189:Retrospective Studies; D015173:Supratentorial Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery; D016019:Survival Analysis