[Relationship between serum fibrosis markers and fibrosis quantitative analysis of liver tissue].
OBJECTIVE
To study relation of serum fibrosis markers with quantitative analysis of liver tissue.


METHODS
We studied the area of reticular fibrin, collagen fibrin and elasticity fibrin in 77 patients with chronic liver disease using color image analysis system.


RESULTS
From S0 to S4, the area of three kinds of liver fibrosis were all escalate, especially collagen fibrosis. Prominent differences existed between S3 and S2, S2 and S1, S1 and S0. There was a good correlation between the serum fibrosis markers and area of collagen fibrosis of liver tissue, r = 0.70775(HA), 0.59402(CIV), 0.52593(LN), 0.52198 (hPCIII).


CONCLUSIONS
Serum fibrosis markers have affirmative value to help diagnose liver fibrosis.
Gu
S
S
Department of Infectious Disease, Nanfang Hospital, Guangzhou.
Zhang
H
H
Zhang
L
L
D000293:Adolescent; D000328:Adult; D015415:Biomarkers; D002648:Child; D003094:Collagen / Q000378:metabolism; D005260:Female; D019694:Hepatitis B, Chronic / Q000097:blood / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology*; D008103:Liver Cirrhosis / Q000145:classification / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged
D015415:Biomarkers; D003094:Collagen