[Probabilistic description of the system "ligand-receptor"].
The theory of probabilities was used to describe the ligand-receptor interaction. Mean and variance of number ligand-receptor complexes are calculated. It is shown that the mean number of ligand-receptor complexes coincides with that obtained from the law of conservation masses. Proceeding from a ratio of mean and expectation it is shown that the variance of the number of ligand-receptor complexes should be taken into account with concentration of ligand-receptor complexes component less than 1 fmol.
Gurevich
K G
KG
Research Center of Psychik Health, Russian Academy of Medical Sciences, Moscow, Russia.
D008024:Ligands; D008954:Models, Biological; D011336:Probability; D011956:Receptors, Cell Surface / Q000737:chemistry*; D013816:Thermodynamics
D008024:Ligands; D011956:Receptors, Cell Surface