The biotransformation of 18-hydroxy-9-epi-ent-pimara-7,15-diene by Gibberella fujikuroi.
Incubation of 18-hydroxy-9-epi-ent-pimara-7,15-diene with the fungus Gibberella fujikuroi gave the compounds 18-hydroxy-7 alpha,8 alpha-epoxy-9-epi-ent-pimara-15-ene, 18-hydroxy-7-oxo-ent-pimara-15-ene, 6 beta, 18-dihydroxy-7 alpha, 8 alpha-epoxy-9-epi-ent-pimara-15-ene, 9 beta,18-dihydroxy-7 alpha, 8 alpha-epoxy-ent-pimara-15-ene and 6 beta, 14 alpha, 18-trihydroxy-9-epi-ent-pimara-7,15-diene. Oxidation of C-19, which is characteristic of the biosynthesis pathway of the gibberellins is not produced.
Fraga
B M
BM
Instituto de Productos Naturales y Agrobiología, Tenerife, Canary Islands, Spain. bmfraga@ipna.csic.es
Hernández
M G
MG
González
P
P
Chamy
M C
MC
Garbarino
J A
JA
D001711:Biotransformation; D004224:Diterpenes / Q000737:chemistry / Q000378:metabolism*; D005874:Gibberella / Q000378:metabolism*; D006900:Hydroxylation; D013057:Spectrum Analysis
D004224:Diterpenes; C099622:pimara-7,15-diene