title: [Changes in the model membrane structure induced by ribonuclease and lysozyme studied by the fluorescent probe technique].
abstract: Using fluorescent probes DSM and DSP-12, the effect of ribonuclease and lysozyme on the structural state of liposomes composed of phosphatidylcholine and diphosphatidylglycerol was studied. A correlation between the changes in probe quantum yield and the amount of protein-bound lipids was established. It is assumed that the formation of protein-lipid complexes increases the packing density of lipids and restricts their mobility. As the content of diphosphatidylglycerol in the lipid bilayer increases, the condensing effect of proteins becomes more pronounced.
authors.affiliation: Kharkov State University, Ukraine.
authors.forename: G P
authors.initials: GP
authors.lastname: Gorbenko
mesh_terms: D002308:Cardiolipins / Q000737:chemistry*; D005456:Fluorescent Dyes; D008081:Liposomes / Q000737:chemistry*; D009113:Muramidase / Q000737:chemistry*; D010713:Phosphatidylcholines / Q000737:chemistry*; D012260:Ribonucleases / Q000737:chemistry*
chemical_list: D002308:Cardiolipins; D005456:Fluorescent Dyes; D008081:Liposomes; D010713:Phosphatidylcholines; D012260:Ribonucleases; D009113:Muramidase