[Structural and functional characteristics of muscle allotransplants, formed under different conditions of laser irradiation].
It is known that a low-energy laser radiation can cause reflex suppression of immunity. The present experiments were designed to determine the plastic activity of allogenic muscle tissue in different conditions of a previous action of laser rays. The cross homotransplantation of gastrocnemius muscles was carried out between intact rats, or between rats in which 14 days before transplantation each hind leg was subjected to low-energy He-Ne laser radiation in dose of 7.5-9 J/cm2 (10 procedures, the duration of each exposure was equal to 5 min), or between intact and radiated rats. It was shown that the donor muscle tissue survived longer when a nonradiated muscle was transplanted into the radiated muscle bed. The axons grew into the donor muscle tissue. More allogenic muscle tissue was involved in contractile reaction when stimulation was carried out via the nerve. Laser radiation of a homotransplant alone, or that of a homotransplant and a muscle bed in the recipient was less effective. So, He-Ne laser radiation of the area of a planned allotransplantation decreased the transplant immunity response and favoured a longer development of allogenic muscle tissue. The viability of donor muscle tissue therewith increased, if the muscle allograft had not been subjected to a previous laser radiation.
Buliakova
N V
NV
Institute of Ecology and Evolution, Russian Academy of Sciences, Moscow.
Azarova
V S
VS
D000818:Animals; D007834:Lasers; D018482:Muscle, Skeletal / Q000502:physiology* / Q000528:radiation effects / Q000637:transplantation; D051381:Rats; D014181:Transplantation Immunology; D014184:Transplantation, Homologous