Effects of kindling in wheat germ agglutinin-horseradish peroxidase [corrected] labeling in neurons of the interamygdaloid pathway in rats.
This paper describes in kindled rats an increment in wheat germ agglutinin-horseradish peroxidase labeling in anterior commissure, bed nuclei of stria terminalis and amygdala. Three groups of animals were analyzed: control, sham-operated and kindled animals with ten convulsive generalized seizures. Results show that kindled animals have an increase in fiber labeling in anterior commissure and in the bed nuclei of stria terminalis, as well as a greater number of labeled neurons in amygdala. This label enhancement is related to the hyperexcitability of neurons produced by epilepsy, and could be associated to the propagation and formation of secondary foci and related plastic changes occurring during kindling.
Martínez-Lorenzana
G
G
Departamento de Neurofisiología, Centro de Neurobiología, Universidad Nacional Autónoma de México, Campus UNAM-Juriquilla, Apartado Postal 1-1141, Querétaro, Mexico.
Talavera-Cuevas
E
E
Sánchez-Alvarez
M
M
Condés-Lara
M
M
D000679:Amygdala / Q000378:metabolism*; D000818:Animals; D004827:Epilepsy / Q000378:metabolism; D006735:Horseradish Peroxidase; D007267:Injections; D007696:Kindling, Neurologic; D008297:Male; D015335:Molecular Probes; D051381:Rats; D017208:Rats, Wistar; D012686:Septal Nuclei / Q000378:metabolism; D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins
D015335:Molecular Probes; D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins; D006735:Horseradish Peroxidase