Antioxidant properties of essential oils. Possible explanations for their anti-inflammatory effects.
Pathogenesis and symptoms of inflammatory processes are accompanied and/or initiated by the production of reactive oxygen species (ROS). The effects of essential oils on these processes have been studied with the aid of biochemical model reactions simulating these pathological events. It can be shown that Myrtol Standardized and Eucalyptus oil ameliorate inflammatory processes by interacting with aggressive oxygen radicals of the OH.-type and interfere with leukocyte activation. These activities partially allow attenuation of oxidative attack and damage introduced by infections or environmental impacts.
Grassmann
J
J
Lehrstuhl für Phytopathologie, Labor für Angewandte Biochemie und Biochemische Toxikologie, Technische Universität München, Freising-Weihenstephan, Germany.
Hippeli
S
S
Dornisch
K
K
Rohnert
U
U
Beuscher
N
N
Elstner
E F
EF
D000596:Amino Acids / Q000737:chemistry; D000598:Amino Acids, Cyclic; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D015550:Cell Degranulation / Q000187:drug effects; D004338:Drug Combinations; D005052:Eucalyptus / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology; D006098:Granulocytes / Q000187:drug effects / Q000648:ultrastructure; D006801:Humans; D066298:In Vitro Techniques; D007202:Indicators and Reagents; D007962:Leukocytes / Q000187:drug effects / Q000378:metabolism; D008715:Methionine / Q000031:analogs & derivatives / Q000737:chemistry; D039821:Monoterpenes; D009566:Nitrates / Q000737:chemistry; D009569:Nitric Oxide / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D016877:Oxidants / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry; D010946:Plants, Medicinal; D013729:Terpenes / Q000737:chemistry
D000596:Amino Acids; D000598:Amino Acids, Cyclic; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000975:Antioxidants; D004338:Drug Combinations; D016166:Free Radical Scavengers; D007202:Indicators and Reagents; D039821:Monoterpenes; D009566:Nitrates; D009822:Oils, Volatile; D016877:Oxidants; D010938:Plant Oils; D013729:Terpenes; C039642:peroxynitric acid; D009569:Nitric Oxide; C023863:1-aminocyclopropane-1-carboxylic acid; C014632:2-keto-4-methylthiobutyric acid; C055632:myrtol; D008715:Methionine