title: Keratosis lichenoides chronica: marked response to calcipotriol ointment.
abstract: Keratosis lichenoides chronica (KCL) is a rare dermatosis characterized by a distinctive seborrheic dermatitis-like facial eruption, together with violaceous, papular, and nodular lesions on the extremities and trunk, typically arranged in a linear and reticulate pattern. KLC is resistant to therapy, although spontaneous remission has been reported. We describe a 35-year-old woman with KLC who had the typical features of widespread violaceous, reticulate, and striae-like eruptions with a prominent keratotic component over a nine-year period and who responded well to treatment with calcipotriol ointment. The immunohistochemical profiles are presented in addition to typical histopathologic features.
authors.affiliation: Department of Dermatology, College of Medicine, University of Ulsan, Seoul, Korea.
authors.forename: S E
authors.initials: SE
authors.lastname: Chang
authors.forename: E C
authors.initials: EC
authors.lastname: Jung
authors.forename: S M
authors.initials: SM
authors.lastname: Hong
authors.forename: J H
authors.initials: JH
authors.lastname: Choi
authors.forename: K J
authors.initials: KJ
authors.lastname: Sung
authors.forename: K C
authors.initials: KC
authors.lastname: Moon
authors.forename: J K
authors.initials: JK
authors.lastname: Koh
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D002117:Calcitriol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002908:Chronic Disease; D012628:Dermatitis, Seborrheic / Q000473:pathology; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005148:Facial Dermatoses / Q000473:pathology; D005260:Female; D006801:Humans; D007642:Keratosis / Q000188:drug therapy* / Q000473:pathology; D017512:Lichenoid Eruptions / Q000188:drug therapy* / Q000473:pathology; D009824:Ointments; D010859:Pigmentation Disorders / Q000473:pathology; D012075:Remission, Spontaneous
chemical_list: D003879:Dermatologic Agents; D009824:Ointments; C055085:calcipotriene; D002117:Calcitriol