title: Acquired segmental megacolon in an adult patient with cystic fibrosis.
abstract: Cystic fibrosis (CF) is characterized by symptoms related to pulmonary dysfunction and pancreatic insufficiency. Constipation, though a frequent complaint of patients with CF, receives less attention. We report a case of acquired segmental megacolon and constipation necessitating surgical colonic resection in an adult patient with CF. The differential diagnosis and possible causes of megacolon in this setting are discussed.
authors.affiliation: Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Davis
authors.forename: C D
authors.initials: CD
authors.lastname: Lind
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003248:Constipation / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D006801:Humans; D008531:Megacolon / Q000209:etiology* / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D020799:Pancrelipase / Q000627:therapeutic use
chemical_list: D005765:Gastrointestinal Agents; D020799:Pancrelipase