Distribution of serotonin in the brain of the Senegalese sole, Solea senegalensis: an immunohistochemical study.
We report the distribution of serotonin immunoreactive (5-HT-ir) structures in the brain of the adult Senegalese sole, Solea senegalensis, using the streptavidin-biotin-peroxidase complex immunohistochemical method. We have found a wide distribution of immunoreactive fibers throughout the entire brain. 5-HT-ir cell bodies appeared restricted to some periventricular nuclei associated with the diencephalic recesses, and in the rhombencephalic reticular formation and inferior olivary region. Specifically, cerebrospinal fluid-contacting serotoninergic cells were found within the pars dorsalis and pars ventralis of the nucleus recessus lateralis, in the paraventricular organ and in the nucleus recessus posterioris. In the brainstem, 5-HT-ir perikarya appear within the superior and inferior raphe, the nucleus reticularis superioris, the nucleus interpeduncularis and the inferior olive. Although positive fibers were not found in the neurohypophysis, a few 5-HT-ir cells were identified in the adenohypophysis. This distribution is compared with those found in other fishes and discussed in the context of putative roles of 5-HT as a neuroendocrine factor and neurotransmitter in the Senegalese sole.
Rodríguez-Gómez
F J
FJ
Department of Animal Biology, Plant Biology and Ecology, Faculty of Marine Sciences, University of Cádiz, Polígono Río San Pedro, 11510, Puerto Real, Cádiz, Spain.
Rendón-Unceta
M C
MC
Sarasquete
C
C
Muñoz-Cueto
J A
JA
D000367:Age Factors; D000818:Animals; D017756:Aquaculture; D001923:Brain Chemistry; D005412:Flatfishes / Q000502:physiology*; D007124:Immunoenzyme Techniques; D009412:Nerve Fibers / Q000737:chemistry; D009490:Neurosecretory Systems / Q000737:chemistry; D012098:Reproduction; D012701:Serotonin / Q000032:analysis*
D012701:Serotonin