Five cases of sarcoidosis in one family: a new immunological link?
We report a family in which five members have been affected with sarcoidosis. The radiological findings of all cases are presented, together with HLA typing, T cell subset and cytokine analysis in four cases. A new HLA association in the presentation of sarcoidosis is suggested.
Elford
J
J
Department of Radiology, Derriford Hospital, Plymouth, UK.
Fitch
P
P
Kaminski
E
E
McGavin
C
C
Wells
I P
IP
D000328:Adult; D005190:Family; D005260:Female; D006650:Histocompatibility Testing; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D017565:Sarcoidosis, Pulmonary / Q000235:genetics / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology