[The wasp-mosquito syndrome: extension of cross-allergenicity to the horsefly].
The crossed allergenicity between wasp venom and mosquito extract was shown during recent work based on clinical observations and correlation studies between different biological parameters, indicating an IgE-dependent biological mechanism. A common protein was identified by Immunoblot. From observation of one of our patients involved in this work, we examined the possibility of the extension of crossed reactivity between wasp, mosquito and horsefly. In effect, our patient presented an anaphylactic reaction with neurological complications from attack on the central grey nucleus, shown by IRM; the immunological study showed a common protein between wasp venom and the total extracts of mosquito and horsefly.
Sabbah
A
A
Laboratoire d'Immuno-Allergologie, CHU, Angers.
Hassoun
S
S
Drouet
M
M
Lauret
M G
MG
Doucet
M
M
D000328:Adult; D000485:Allergens / Q000009:adverse effects* / Q000276:immunology / Q000302:isolation & purification; D000707:Anaphylaxis / Q000209:etiology; D000818:Animals; D001480:Basal Ganglia Diseases / Q000209:etiology; D015549:Basophil Degranulation Test; D001925:Brain Damage, Chronic / Q000209:etiology; D003429:Cross Reactions; D009033:Culicidae / Q000737:chemistry / Q000276:immunology*; D003680:Deglutition Disorders / Q000209:etiology; D004175:Diptera / Q000737:chemistry / Q000276:immunology*; D006429:Hemiplegia / Q000209:etiology; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007299:Insect Bites and Stings / Q000276:immunology*; D019476:Insect Proteins / Q000009:adverse effects* / Q000276:immunology / Q000302:isolation & purification; D008297:Male; D013045:Species Specificity; D014862:Wasp Venoms / Q000737:chemistry / Q000276:immunology; D014863:Wasps / Q000737:chemistry / Q000276:immunology*
D000485:Allergens; D019476:Insect Proteins; D014862:Wasp Venoms; D007073:Immunoglobulin E