title: Postoperative pulpal and repair responses.
abstract: BACKGROUND
  Each year in the United States, the success of 10 million surgically restored carious lesions depends on a favorable tertiary dentin repair response to preparation, restoration and patient factor variables. The authors investigated the relationship between these variables and dentinal response.
  
  
  METHODS
  Standardized rectangular Class V restoration preparations were cut into the buccal dentin of intact first or second premolars of 27 patients without exposing the pulp and were restored. The patients were between 9 and 17 years of age. The treated teeth were scheduled for extraction for orthodontic reasons. After tooth extraction, the tertiary dentin was analyzed histomorphometrically.
  
  
  RESULTS
  The area of tertiary reactionary dentin was found to be correlated using linear regression analysis of variance with restoration residual dentin thickness (P = .0024), age of the patient (P = .0045), restoration floor surface area (P = .0266) and restoration width (P = .0415). The authors did not find a correlation with the premolar position (P = .0594), sex of the patient (P = .650), pulpal inflammatory reaction (P = .613) or the time elapsed since surgery (P = .531). Restoration with zinc oxide eugenol was found to negatively influence tertiary dentin matrix secretion (post hoc analysis of variance, P = .030).
  
  
  CONCLUSIONS
  The age of a patient at treatment, the choice of restorative material and the size of the restoration preparation are all factors that can positively or negatively affect the pulpal repair response.
  
  
  CONCLUSIONS
  Age of the patient affects dentin repair capacity and may be a factor in treatment planning decisions. Minimizing the cutting of dentin, especially the width and base of the preparation, reduces the probability of recurrent pulpal complications.
authors.affiliation: School of Dentistry, University of Birmingham, England.
authors.forename: P E
authors.initials: PE
authors.lastname: Murray
authors.forename: I
authors.initials: I
authors.lastname: About
authors.forename: P J
authors.initials: PJ
authors.lastname: Lumley
authors.forename: G
authors.initials: G
authors.lastname: Smith
authors.forename: J C
authors.initials: JC
authors.lastname: Franquin
authors.forename: A J
authors.initials: AJ
authors.lastname: Smith
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000704:Analysis of Variance; D002648:Child; D003782:Dental Pulp / Q000473:pathology*; D003793:Dental Restoration, Permanent / Q000009:adverse effects / Q000379:methods; D003804:Dentin / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000473:pathology*; D011671:Pulpitis / Q000473:pathology*; D013997:Time Factors