Binaural interaction component and white-noise enhancement in middle latency responses: differential effects of anaesthesia in guinea pigs.
It is known that the response to binaural clicks is smaller in amplitude than the sum of two monaural responses. The difference is called the binaural interaction component (BIC). Also, an amplitude enlargement occurs in guinea pig middle latency responses (MLRs) to monaural clicks when white noise is applied to the other ear. This study was conducted to find out whether these two signs of binaural interaction result from the same mechanism. White noise enhancement (WNE) and BIC were computed from the evoked potential data simultaneously recorded in different phases of anaesthesia. WNE gradually decreased and disappeared with anaesthesia, but the relative amplitude of the BIC remained unchanged. This differential effect showed that different neural mechanisms must be responsible for BIC and WNE in guinea pig MLR.
Goksoy
C
C
Department of Biophysics, Gulhane Military Medical Academy, Etlik/Ankara, Turkey. cg02-k@tr-net.net.tr
Utkucal
R
R
D000161:Acoustic Stimulation; D000758:Anesthesia; D000818:Animals; D001306:Auditory Pathways / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology*; D001309:Auditory Threshold / Q000502:physiology; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D007839:Functional Laterality; D006168:Guinea Pigs; D011930:Reaction Time / Q000502:physiology*; D013017:Sound Localization / Q000502:physiology*