title: Successful management of a viable cervical pregnancy by single-dose methotrexate.
abstract: Cervical pregnancy is very uncommon and carries a high risk for hysterectomy with surgical treatment. Prior reports of medical treatment included various regimens of high-dose systemic methotrexate (MTX) with citrovorum rescue and local injection. This is the first report of successfully treating a viable cervical pregnancy with single-dose i.m. MTX, followed by a vaginal delivery.
authors.affiliation: Department of Gynecology, The Cleveland Clinic Foundation, Ohio 44195, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Goldberg
authors.forename: T
authors.initials: T
authors.lastname: Widrich
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage*; D000328:Adult; D002584:Cervix Uteri; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008727:Methotrexate / Q000008:administration & dosage*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy*
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate