[Electrotonic conduction of excitation and inhibition along the dendritic fiber with the uniformly distributed synaptic conductance].
The existence of an optimum radius of fibre is shown, when the physical parameters of the intracellular medium and the nonexcitable dendritic membrane are known and the length and load resistance are fixed. This provides the maximum potential for the proximal end of the fibre if synaptic conductance is distributed uniformly along the fibre. A formula for calculating the soma potential of the whole neuron is proposed. The optimal ratio l/lambda is 0.9193 ... if the volume of the fibre and synaptic conductivity are fixed.
Manianin
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Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia.
D000465:Algorithms; D003712:Dendrites / Q000502:physiology* / Q000648:ultrastructure; D008954:Models, Biological; D009412:Nerve Fibers / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*