[Diabetes mellitus type I, celiac disease and Imerslund-Gräsbeck syndrome: only an incidental combination of rare diseases?].
We describe the clinical course of a girl with onset of type I diabetes mellitus at the age of 3 years. At the age of 10, coeliac disease and shortly thereafter a vitamin B12 deficiency anemia (Imerslund-Gräsbeck-syndrome) was diagnosed. Her younger sister also suffered from Imerslund-Gräsbeck-syndrome when she was 11 year old. This unusual, so far not described association of rare diseases suggests a common autoimmune etiology.
Schröder
A
A
Universitätsklinik Göttingen.
Witt
O
O
Eber
S
S
D000752:Anemia, Pernicious / Q000175:diagnosis / Q000209:etiology*; D002446:Celiac Disease / Q000150:complications* / Q000178:diet therapy / Q000276:immunology; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003937:Diagnosis, Differential; D004827:Epilepsy / Q000209:etiology; D005260:Female; D005492:Folic Acid / Q000097:blood / Q000627:therapeutic use; D015803:HLA-DR3 Antigen / Q000097:blood; D006801:Humans; D007275:Injections, Intravenous; D007621:Karyotyping; D011507:Proteinuria / Q000209:etiology; D012546:Schilling Test; D013577:Syndrome; D014805:Vitamin B 12 / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use* / Q000652:urine; D014806:Vitamin B 12 Deficiency / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy* / Q000652:urine
D015803:HLA-DR3 Antigen; D005492:Folic Acid; D014805:Vitamin B 12