Tactile stimulation activates dopamine release in the lateral septum.
Little is known about the functional properties of the dopamine innervation of the lateral septum. In this study, the feasibility of using microdialysis to assess action-potential mediated release of dopamine in the lateral septum was established. A mild stressor, in the form of handling, significantly increased septal dopamine levels, implicating a role for dopamine in sensory-related processing associated with the septal complex.
Adams
B W
BW
Department of Psychiatry, Yale University School of Medicine, VA Medical Center 116A/2, West Haven, CT 06516, USA.
Moghaddam
B
B
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004298:Dopamine / Q000032:analysis / Q000378:metabolism*; D005110:Extracellular Space / Q000378:metabolism; D005240:Feasibility Studies; D006234:Handling, Psychological; D008297:Male; D017551:Microdialysis; D010812:Physical Stimulation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012686:Septal Nuclei / Q000187:drug effects / Q000378:metabolism*; D013312:Stress, Physiological / Q000378:metabolism; D013779:Tetrodotoxin / Q000494:pharmacology
D013779:Tetrodotoxin; D004298:Dopamine