Synthesis and antibacterial activity of 1-(3-hydroxy-2-naphthoyl)-4-substituted thiosemicarbazides.
1-(3-Hydroxy-2-naphthoyl)-4-substituted thiosemicarbazides were obtained by the addition of 3-hydroxy-2-naphthoic acid hydrazide to various isothiocyanates. The structures of the synthesized compounds were confirmed using UV and 1H-NMR spectral methods together with elemental analysis.
Doğan
H N
HN
Marmara University, Faculty of Pharmacy, Pharmaceutical Chemistry Department, Istanbul.
Duran
A
A
Yemni
E
E
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D007709:Klebsiella / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011511:Proteus / Q000187:drug effects; D011549:Pseudomonas / Q000187:drug effects; D012663:Semicarbazides / Q000138:chemical synthesis / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D012663:Semicarbazides