[Cloning and sequence analysis of human genomic DNA of augmenter of liver regeneration hepatitis].
OBJECTIVE
To clone the human genomic DNA of augmenter of liver regeneration (ALR) and specify the intron-exon structure.


METHODS
Using human ALR cDNA sequence as a reference and BLAST path as a nucleotide homology search tool, GenBank has been searched for ALR homologous genomic DNA sequence. The intron-exon sequences were defined by the Breathnath-Chambon rule.


RESULTS
The coding sequence of human ALR consists of 3 exons, and is similar to murine ALR genomic DNA structure. The human ALR genomic DNA is 1813 nt long and codes a protein of 125 amino acid residues.


CONCLUSIONS
Human genomic DNA of ALR consists of 3 exons and 2 introns.
Cheng
J
J
Gene Therapy Research Center, Institute of Infectious Diseases, the 302 Hospital of PLA, Beijing 100039, China.
Zhong
Y
Y
D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000737:chemistry*; D005091:Exons; D006133:Growth Substances / Q000235:genetics*; D006801:Humans; D007438:Introns; D008115:Liver Regeneration; D008969:Molecular Sequence Data
D018076:DNA, Complementary; D006133:Growth Substances