title: Latex hypersensitivity in a child with diabetes.
abstract: BACKGROUND
  A 6-year-old girl who was diagnosed with diabetes mellitus 20 months previously developed erythematous, raised lesions at the site of her insulin injections. The reactions occurred when isophane and lispro insulin were administered individually or combined but not when insulin was obtained from the bottle after the septum had been removed.
  
  
  OBJECTIVE
  To describe latex hypersensitivity in a child with diabetes and to review the literature.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  Findings from intradermal testing confirmed latex hypersensitivity. A change to insulin administration by insulin pen decreased the frequency of the reactions.
  
  
  CONCLUSIONS
  Latex hypersensitivity should be considered in children with type 1 diabetes who develop local reactions to insulin injections.
authors.affiliation: Department of Pediatrics, University of Iowa College of Medicine, Iowa City 52242, USA. robert-hoffman@uiowa.edu
authors.forename: R P
authors.initials: RP
authors.lastname: Hoffman
mesh_terms: D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D004349:Drug Packaging; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous / Q000295:instrumentation*; D007328:Insulin / Q000008:administration & dosage*; D007428:Intradermal Tests; D020315:Latex Hypersensitivity / Q000175:diagnosis* / Q000276:immunology
chemical_list: D007328:Insulin