title: Disinfection potential of electrolyzed solutions containing sodium chloride at low concentrations.
abstract: Electrolyzed products of sodium chloride solution were examined for their disinfection potential against hepatitis B virus (HBV) and human immunodeficiency virus (HIV) in vitro. Electrolysis of 0.05% NaCl in tap water was carried out for 45 min at room temperature using a 3 A electric current in separate wells installed with positive and negative electrodes. The electrolyzed products were obtained from the positive well. The oxidation reduction potential (ORP), pH and free chlorine content of the product were 1053 mV, pH 2.34 and 4.20 ppm, respectively. The products modified the antigenicity of the surface protein of HBV as well as the infectivity of HIV in time- and concentration-dependent manner. Although the inactivating potential was decreased by the addition of contaminating protein, recycling of the product or continuous addition of fresh product may restore the complete disinfection against bloodborne pathogens.
authors.affiliation: Department of Microbiology, Osaka Medical College, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Morita
authors.forename: K
authors.initials: K
authors.lastname: Sano
authors.forename: S
authors.initials: S
authors.lastname: Morimatsu
authors.forename: H
authors.initials: H
authors.lastname: Kiura
authors.forename: T
authors.initials: T
authors.lastname: Goto
authors.forename: T
authors.initials: T
authors.lastname: Kohno
authors.forename: W U
authors.initials: WU
authors.lastname: Hong
authors.forename: H
authors.initials: H
authors.lastname: Miyoshi
authors.forename: A
authors.initials: A
authors.lastname: Iwasawa
authors.forename: Y
authors.initials: Y
authors.lastname: Nakamura
authors.forename: M
authors.initials: M
authors.lastname: Tagawa
authors.forename: O
authors.initials: O
authors.lastname: Yokosuka
authors.forename: H
authors.initials: H
authors.lastname: Saisho
authors.forename: T
authors.initials: T
authors.lastname: Maeda
authors.forename: Y
authors.initials: Y
authors.lastname: Katsuoka
mesh_terms: D000143:Acids; D001288:Attention; D002460:Cell Line; D004203:Disinfection / Q000379:methods*; D004572:Electrolysis; D015497:HIV-1; D006515:Hepatitis B virus; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010084:Oxidation-Reduction; D012965:Sodium Chloride / Q000737:chemistry; D012996:Solutions
chemical_list: D000143:Acids; D012996:Solutions; D012965:Sodium Chloride