title: The nose as bacterial reservoir: important differences between the vestibule and cavity.
abstract: The difference between the spectra of potential bacterial pathogens (PBPs) in the nasal vestibule and cavity has not been taken into account in clinical studies.
  
  
  OBJECTIVE
  Since one can anticipate different flora in different kinds of mucosae, the authors compared bacterial species in the vestibule with those of the cavity.
  
  
  METHODS
  A total of 534 healthy male clerical workers in a downtown Lucerne office building were examined with fractionated swabs.
  
  
  RESULTS
  PBPs, notably Staphylococcus aureus, were found in 412 subjects and surprisingly, differences in flora of the two sites were noted in 130 of them: PBPs were observed in the vestibule and not in the cavity in 85 of the subjects, and in 45 of them, the reverse was true.
  
  
  CONCLUSIONS
  The practical implications of these findings are considerable regarding infection control in patients at increased infection risk.
authors.affiliation: Suva Swiss National Accident Insurance Institute, Division of Occupational Medicine, Kantonsspital Luzerne, Lucerne, Switzerland. u_gluck@yahoo.de
authors.forename: U
authors.initials: U
authors.lastname: Glück
authors.forename: J O
authors.initials: JO
authors.lastname: Gebbers
mesh_terms: D000328:Adult; D001419:Bacteria / Q000145:classification* / Q000254:growth & development; D002176:Candida albicans / Q000254:growth & development; D002954:Citrobacter / Q000254:growth & development; D016001:Confidence Intervals; D016972:Enterobacter cloacae / Q000254:growth & development; D004926:Escherichia coli / Q000254:growth & development; D006190:Haemophilus / Q000254:growth & development; D006193:Haemophilus influenzae / Q000254:growth & development; D006801:Humans; D007709:Klebsiella / Q000254:growth & development; D008297:Male; D016106:Methicillin Resistance; D008875:Middle Aged; D009296:Nasal Cavity / Q000382:microbiology*; D009297:Nasal Mucosa / Q000382:microbiology; D009666:Nose / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000254:growth & development