title: Prolonged coma due to cerebral fat embolism: report of two cases.
abstract: Fat embolism syndrome remains a rare, but potentially life threatening complication of long bone fractures. The true incidence is difficult to assess as many cases remain undiagnosed. Cerebral involvement varies from confusion to encephalopathy with coma and seizures. Clinical symptoms and computed tomography are not always diagnostic, while magnetic resonance imaging is more sensitive in the detection of a suspected brain embolism. Two cases of post-traumatic cerebral fat embolism, manifested by prolonged coma and diffuse cerebral oedema, are presented. The clinical course of the disease as well as the intensive care unit management are discussed.
authors.affiliation: Intensive Care Unit, Athens Trauma Hospital, Greece.
authors.forename: L
authors.initials: L
authors.lastname: Gregorakos
authors.forename: K
authors.initials: K
authors.lastname: Sakayianni
authors.forename: D
authors.initials: D
authors.lastname: Hroni
authors.forename: V
authors.initials: V
authors.lastname: Harizopoulou
authors.forename: N
authors.initials: N
authors.lastname: Markou
authors.forename: F
authors.initials: F
authors.lastname: Georgiadou
authors.forename: M
authors.initials: M
authors.lastname: Adamidou
mesh_terms: D000293:Adolescent; D000328:Adult; D003128:Coma / Q000209:etiology*; D004620:Embolism, Fat / Q000150:complications / Q000209:etiology*; D006801:Humans; D020766:Intracranial Embolism / Q000150:complications / Q000209:etiology*; D008297:Male; D013978:Tibial Fractures / Q000150:complications*; D013997:Time Factors