title: [EFR-like peptides and their receptors as prognostic factors for the survival of patients with non-small-cell lung cancer].
abstract: The levels of EGFR and its ligands have been assayed in tumor and adjacent lung tissues in NSCLC patients. Both EGFR and EGF-like peptides were found in tumor more frequently than in unaltered tissue. It was shown (Kaplan-Meyer) that simultaneous expression of EGFR and its ligands in tumor and adjacent lung tissues was associated with lower overall and relapse-free survival in NSCLC patients.
authors.affiliation: N.N. Blokhin Center for Cancer Research, Russian Academy of Medical Sciences, Moscow.
authors.forename: O I
authors.initials: OI
authors.lastname: Kostyleva
authors.forename: E S
authors.initials: ES
authors.lastname: Gerstein
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Dykhno
authors.forename: A V
authors.initials: AV
authors.lastname: Vasil'ev
authors.forename: B E
authors.initials: BE
authors.lastname: Polotskiĭ
authors.forename: N E
authors.initials: NE
authors.lastname: Kushlinskiĭ
mesh_terms: D000328:Adult; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000737:chemistry* / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology; D004815:Epidermal Growth Factor / Q000032:analysis*; D066246:ErbB Receptors / Q000032:analysis*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000737:chemistry* / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D016019:Survival Analysis
chemical_list: D004815:Epidermal Growth Factor; D066246:ErbB Receptors