title: A three-dimensional mechanical analysis of a stentless fibre-reinforced aortic valve prosthesis.
abstract: Failure of bioprosthetic and synthetic three-leaflet valves has been shown to occur as a consequence of high tensile and bending stresses, acting on the leaflets during opening and closing. Moreover, in the stented prostheses, whether synthetic or biological, the absence of contraction of the aortic base, due to the rigid stent, causes the leaflets to be subjected to an unphysiological degree of flexure, which is related to calcification. It is shown that the absence of the stent, which gives a flexible aortic base and leaflet attachment, and leaflet fibre-reinforcement result in reduced stresses in the weaker parts of the leaflets in their closed configuration. It is postulated that this leads to a decrease of tears and perforations, which may result in a improved long-term behaviour. The effect of a flexible leaflet attachment and aortic base of a synthetic valve is investigated with a finite element model. Different fibre-reinforced structures are analysed with respect to the stresses that are likely to contribute to the failure of fibre-reinforced prostheses and compared with the results obtained for a stented prosthesis. Results show that for the stentless models a reduction of stresses up to 75% is obtained with respect to stented models with the same type of reinforcement.
authors.affiliation: Department of Mechanical Engineering, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands. giovanna@wfw.wtb.tue.nl
authors.forename: G
authors.initials: G
authors.lastname: Cacciola
authors.forename: G W
authors.initials: GW
authors.lastname: Peters
authors.forename: P J
authors.initials: PJ
authors.lastname: Schreurs
mesh_terms: D001021:Aortic Valve; D006350:Heart Valve Prosthesis; D006801:Humans; D011474:Prosthesis Design; D015607:Stents; D013314:Stress, Mechanical