title: Cytomegalovirus infection may cause ureteral necrosis.
abstract: Cytomegalovirus (CMV) infection has protean presentation among immunocompromised patients, but the urinary tract is rarely involved. We report a case of extensive ureteral necrosis in a renal transplant, 12-year-old patient with typical histological feature of CMV inclusions. The role of CMV was confirmed by immunohistochemical analysis and concomitant CMV DNA detection in peripheral blood leukocytes by polymerase chain reaction analysis. CMV infection can, therefore, be regarded as a possible cause of ureteral necrosis in renal transplant recipients.
authors.affiliation: Département de Pédiatrie, Hôpital Edouard Herriot and Université Claude Bernard, Lyon, France.
authors.forename: N
authors.initials: N
authors.lastname: Peretti
authors.forename: M H
authors.initials: MH
authors.lastname: Saïd
authors.forename: R
authors.initials: R
authors.lastname: Bouvier
authors.forename: P C
authors.initials: PC
authors.lastname: Koch-Nogueira
authors.forename: D
authors.initials: D
authors.lastname: Thouvenot
authors.forename: X
authors.initials: X
authors.lastname: Martin
authors.forename: P
authors.initials: P
authors.lastname: Cochat
mesh_terms: D002648:Child; D003586:Cytomegalovirus Infections / Q000150:complications*; D005919:Glomerular Filtration Rate; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D009336:Necrosis; D014513:Ureter / Q000473:pathology*; D014515:Ureteral Diseases / Q000473:pathology* / Q000821:virology*