Keratosis lichenoides chronica: marked response to calcipotriol ointment.
Keratosis lichenoides chronica (KCL) is a rare dermatosis characterized by a distinctive seborrheic dermatitis-like facial eruption, together with violaceous, papular, and nodular lesions on the extremities and trunk, typically arranged in a linear and reticulate pattern. KLC is resistant to therapy, although spontaneous remission has been reported. We describe a 35-year-old woman with KLC who had the typical features of widespread violaceous, reticulate, and striae-like eruptions with a prominent keratotic component over a nine-year period and who responded well to treatment with calcipotriol ointment. The immunohistochemical profiles are presented in addition to typical histopathologic features.
Chang
S E
SE
Department of Dermatology, College of Medicine, University of Ulsan, Seoul, Korea.
Jung
E C
EC
Hong
S M
SM
Choi
J H
JH
Sung
K J
KJ
Moon
K C
KC
Koh
J K
JK
D000279:Administration, Cutaneous; D000328:Adult; D002117:Calcitriol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002908:Chronic Disease; D012628:Dermatitis, Seborrheic / Q000473:pathology; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005148:Facial Dermatoses / Q000473:pathology; D005260:Female; D006801:Humans; D007642:Keratosis / Q000188:drug therapy* / Q000473:pathology; D017512:Lichenoid Eruptions / Q000188:drug therapy* / Q000473:pathology; D009824:Ointments; D010859:Pigmentation Disorders / Q000473:pathology; D012075:Remission, Spontaneous
D003879:Dermatologic Agents; D009824:Ointments; C055085:calcipotriene; D002117:Calcitriol