[Cytomechanical control of morphogenesis].
The role of mechanically strained state of cells and multicellular structures in morphogenesis regulating in vertebrate embryos is discussed. Regular changes in patterns of mechanical strain during embryonic development are described. Artificial relaxation of mechanical strain performed on definite developmental stages and retension of embryonic tissues in arbitrary directions considerably affects morphogenesis and cell differentiation patterns. Cytomechanical models of morphogenesis are reviewed and a concept of hyperrestoration of mechanical strain as a possible driving force of morphogeneiss is suggested.
Belousov
L V
LV
Moscow State University. lbelous@soil.msu.ru
Ermakov
A S
AS
Luchinskaia
N N
NN
D000818:Animals; D019521:Body Patterning; D004625:Embryo, Nonmammalian / Q000166:cytology*; D009024:Morphogenesis; D014714:Vertebrates / Q000196:embryology*