title: Phytotoxicity to and uptake of flumequine used in intensive aquaculture on the aquatic weed, Lythrum salicaria L.
abstract: Phytotoxicity of Flumequine on the aquatic weed Lythrum salicaria L. was determined by two laboratory models: a single concentration test, by which the effects of 100 mg l-1 were evaluated after 10, 20, 30 days and a multiple concentration test, by which the effects of 5000-1000-500-100-50 micrograms l-1 were evaluated after 35-day exposure. 100 mg l-1 are highly toxic and significantly decrease the growth of plants; this effect increases with time. Concentrations between 5000 and 50 micrograms l-1 induced hormesis in plants, by significantly increasing mean number and dimension of leaves and secondary roots. The effect is the highest at 50 micrograms l-1 and decreases with increase in concentration. Both toxic effect and hormesis can be related to plant drug uptake, quite high, in the order of micrograms g-1. The ecological implication of Flumequine contamination in aquatic environments and the possible use of Lythrum salicaria for bioremediation and/or monitoring technique are discussed.
authors.affiliation: Dipartimento di Biologia, Università Tor Vergata, Roma, Italy. luciana.migliore@uniroma2.it
authors.forename: L
authors.initials: L
authors.lastname: Migliore
authors.forename: S
authors.initials: S
authors.lastname: Cozzolino
authors.forename: M
authors.initials: M
authors.lastname: Fiori
mesh_terms: D000890:Anti-Infective Agents / Q000493:pharmacokinetics / Q000633:toxicity*; D017756:Aquaculture; D024841:Fluoroquinolones; D063245:Plant Development; D010944:Plants / Q000187:drug effects*; D011807:Quinolizines / Q000493:pharmacokinetics / Q000633:toxicity*; D018675:Toxicity Tests / Q000379:methods; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics / Q000633:toxicity*
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D011807:Quinolizines; D014874:Water Pollutants, Chemical; C012976:flumequine