[Changes in the enzyme activity in the brain structures of August rats under the influence of the delta sleep-inducing peptide against a background of prolonged L-dihydroxyphenylalanine administration].
Quantitative cytochemical methods revealed the decrease of MAO activity (substrate--tryptamine) in the hippocampus of L-dioxytryptamine treated August rats genetically predisposed to emotional stress under the effect of delta sleep inducing peptide (DSIP). Activities of aminopeptidase and glutamate dehydrogenase were decreased in n.accumbens while changes of the activities of these enzymes were not significant in the layers III and V of sensomotor cortex and n.caudatus. In all brain structures Ache and MAO (substrate 5-hydroxytryptamine) activities were not influenced by DSIP.
Sergutina
A V
AV
Laboratory of Cytochemistry, Brain Research Institute, RAMS, Moscow.
Rakhmanova
V I
VI
D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000201:enzymology*; D001923:Brain Chemistry / Q000187:drug effects; D003701:Delta Sleep-Inducing Peptide / Q000494:pharmacology*; D015259:Dopamine Agents / Q000494:pharmacology*; D006651:Histocytochemistry; D007980:Levodopa / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D015259:Dopamine Agents; D007980:Levodopa; D003701:Delta Sleep-Inducing Peptide