title: Repair of late retinal detachment after successful treatment of retinoblastoma.
abstract: OBJECTIVE
  To analyze the results of vitreous surgery for late retinal detachment (RD) after successful treatment of retinoblastoma.
  
  
  METHODS
  The records of all patients with retinoblastoma seen at a single ocular oncology service between 1982 and 1998 were reviewed to identify patients treated for late RD. Previous treatments, characteristics of the RD, surgical techniques used, and visual and anatomic results of the surgery were recorded.
  
  
  RESULTS
  Of more than 500 charts reviewed, four patients treated for late RD were identified. All four had received previous, whole-eye, external beam radiotherapy and subsequently required cataract surgery. Other previous treatments included radioactive plaque, cryotherapy, xenon photocoagulation, and chemotherapy. At presentation, some patients had shifting subretinal fluid. None had a tear identifiable preoperatively, but two patients had a definite small slit tear at a tumor edge identified at surgery. One patient had a primary scleral buckle that failed. All patients had vitreous surgery with silicone oil. Average postsurgical follow-up was 30 months. Preoperative visual acuity ranged from 20/80 to light perception and improved postoperatively in two patients. The retina remained completely attached in three patients.
  
  
  CONCLUSIONS
  Despite shifting subretinal fluid and no identifiable tear, a rhegmatogenous RD should be considered if it occurs late in patients with otherwise stable, treated retinoblastoma. Tumor reactivation must be excluded carefully. Vitreous surgery can be used to repair the RD successfully and improve vision.
authors.affiliation: Center for Vision Research, Department of Ophthalmology, Case Western Reserve University, Cleveland, Ohio, USA.
authors.forename: S A
authors.initials: SA
authors.lastname: Madreperla
authors.forename: J L
authors.initials: JL
authors.lastname: Hungerford
authors.forename: R J
authors.initials: RJ
authors.lastname: Cooling
authors.forename: P
authors.initials: P
authors.lastname: Sullivan
authors.forename: Z
authors.initials: Z
authors.lastname: Gregor
mesh_terms: D002675:Child, Preschool; D003131:Combined Modality Therapy; D006801:Humans; D007223:Infant; D007267:Injections; D053685:Laser Therapy; D012163:Retinal Detachment / Q000209:etiology / Q000601:surgery*; D019572:Retinal Neoplasms / Q000150:complications / Q000628:therapy*; D012175:Retinoblastoma / Q000150:complications / Q000628:therapy*; D012189:Retrospective Studies; D012591:Scleral Buckling / Q000379:methods; D012827:Silicone Oils / Q000008:administration & dosage; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods; D014822:Vitreous Body
chemical_list: D012827:Silicone Oils