title: Traumatic Acremonium atrogriseum keratitis following laser-assisted in situ keratomileusis.
abstract: A 52-year-old man underwent bilateral laser-assisted in situ keratomileusis. Eight months later, he sustained a penetrating corneal injury to the left eye. A dense white infiltrate, unresponsive to antimicrobial therapy, developed in the corneal stroma. Corneal biopsy and eventual penetrating keratoplasty were performed, and both specimens demonstrated fungal elements with branching, septate hyphae. Culture identified the organism as Acremonium atrogriseum. Histopathologic features of this organism and its differentiation from other, more common fungal organisms are discussed herein.
authors.affiliation: Doheny Eye Institute and the Department of Ophthalmology, Keck School of Medicine at the University of Southern California, Los Angeles 90033, USA.
authors.forename: R W
authors.initials: RW
authors.lastname: Read
authors.forename: R S
authors.initials: RS
authors.lastname: Chuck
authors.forename: N A
authors.initials: NA
authors.lastname: Rao
authors.forename: R E
authors.initials: RE
authors.lastname: Smith
mesh_terms: D000164:Acremonium / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents; D001706:Biopsy; D003315:Cornea / Q000382:microbiology / Q000601:surgery; D065306:Corneal Injuries; D003319:Corneal Stroma / Q000382:microbiology / Q000473:pathology; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D015821:Eye Infections, Fungal / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D015807:Eye Injuries, Penetrating / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D006956:Hyperopia / Q000601:surgery; D007634:Keratitis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D020731:Keratomileusis, Laser In Situ; D015948:Keratoplasty, Penetrating; D008297:Male; D008875:Middle Aged; D013524:Surgical Flaps / Q000382:microbiology / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents