title: Risk factors in prostatectomy bleeding: preoperative urinary infection is the only reversible factor.
abstract: OBJECTIVE
  To find out whether any of a preset battery of clinical and laboratory parameters has significant correlation with blood loss caused by transurethral prostatectomy (TURP).
  
  
  METHODS
  All new patients undergoing a TURP over a 1-year period were included in the study. For each patient the following parameters were documented: (1) Pre-operatively: Age, mode of presentation, blood pressure, complete blood count, coagulation screening, calcification of abdominal blood vessels on plain X-ray, prostate size on digital rectal examination (DRE), pre-operative urine culture, presence of haematuria, ECG changes and drugs taken. (2) Intraoperatively: prostate morphology at cystoscopy, type of anaesthesia, operating surgeon, operating time, weight of resected prostate tissue and any blood transfusions. (3) Postoperatively: Length of irrigation time and prostate histology. All the intra-operative and postoperative blood loss was calculated. Their sum constituted total blood loss which constituted the dependent variable of the study. Statistical methods used included bivariate correlation, Students t test or the chi(2) test as appropriate.
  
  
  RESULTS
  Of 140 TURPs, 121 were eligible for final analysis. The mean total blood loss was 552 ml (34 ml per gram of tissue) and the mean resected prostate weight was 18 g. Of the continuous variables, the one with strongest correlation with total blood loss was resected prostate weight (r = 0.47, p = 0.000) followed by prostate size on DRE (r = 0.45, p = 0.000) then operating time (r = 0.39, p = 0.000). Of the categorical variables, the one with the strongest correlation with total blood loss was preoperative urine culture (p = 0.01).
  
  
  CONCLUSIONS
  The only reversible factor associated with blood loss caused by TURP is pre-operative urinary infection. Operating time is partly controllable, as it may improve (i.e. decrease) with experience of the operator.
authors.affiliation: Department of, Surgery, College of Medicine, King Khalid University, Abha, Saudi Arabia.
authors.forename: E M
authors.initials: EM
authors.lastname: ElMalik
authors.forename: A I
authors.initials: AI
authors.lastname: Ibrahim
authors.forename: A M
authors.initials: AM
authors.lastname: Gahli
authors.forename: M S
authors.initials: MS
authors.lastname: Saad
authors.forename: Y M
authors.initials: YM
authors.lastname: Bahar
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000453:epidemiology* / Q000209:etiology*; D011300:Preoperative Care; D012307:Risk Factors; D020728:Transurethral Resection of Prostate / Q000009:adverse effects*; D014552:Urinary Tract Infections / Q000150:complications*