title: Evaluation of serological status of rubella & mumps in children below five years.
abstract: A cross-sectional study was carried out on 321 serum samples to detect rubella and mumps antibodies in children below five years and to assess the optimum age for immunization against rubella and mumps. Seropositivity to rubella was 33.3 per cent in children below nine months, 16.9 per cent at 9-12 months and 25.5 per cent by two years. Mean antibody levels for rubella were low at nine months to one year and remained so till five years of age. Similarly, seropositivity for mumps was 53.3 per cent below nine months, 20.3 per cent at 9-12 months and 40 per cent by two years. Mean antibody levels for mumps were low between nine months to two years with a slight rise by five years. The findings suggest that a large majority of children are at risk by the age of nine months in our population and the measles, mumps and rubella (MMR) vaccination at this age may be most beneficial.
authors.affiliation: Department of Microbiology, Maulana Azad Medical College, New Delhi.
authors.forename: A
authors.initials: A
authors.lastname: Chakravarti
authors.forename: S
authors.initials: S
authors.lastname: Yadav
authors.forename: N
authors.initials: N
authors.lastname: Berry
authors.forename: A
authors.initials: A
authors.lastname: Rastogi
authors.forename: M D
authors.initials: MD
authors.lastname: Mathur
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005069:Evaluation Studies as Topic; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009107:Mumps / Q000276:immunology* / Q000517:prevention & control; D009108:Mumps Vaccine / Q000008:administration & dosage; D012409:Rubella / Q000276:immunology* / Q000517:prevention & control; D012411:Rubella Vaccine / Q000008:administration & dosage
chemical_list: D000914:Antibodies, Viral; D009108:Mumps Vaccine; D012411:Rubella Vaccine