Epstein-Barr virus dacryoadenitis.
OBJECTIVE
To describe the clinical features of lacrimal gland inflammation associated with Epstein-Barr virus infection.


METHODS
The clinical records, laboratory data, and radiographs of patients who had inflammation of one or both lacrimal glands that had begun less than 4 weeks previously were reviewed.


RESULTS
Sixteen patients with dacryoadenitis were encountered between 1980 and 1996, a cumulative frequency of approximately one case per 10,000 new ophthalmic outpatients. Six individuals had serologic or other evidence of recent Epstein-Barr virus infection and were distinguished by the presence of regional lymphadenopathy, no purulent discharge, and a duration of symptoms of 6 weeks.


CONCLUSIONS
Epstein-Barr virus is a probable cause of unilateral and bilateral dacryoadenitis in young adults.
Rhem
M N
MN
Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA.
Wilhelmus
K R
KR
Jones
D B
DB
D000293:Adolescent; D000328:Adult; D000368:Aged; D000956:Antigens, Viral / Q000276:immunology; D002213:Capsid / Q000276:immunology; D036022:Capsid Proteins; D002506:Cephalexin / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003607:Dacryocystitis / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006566:Herpesviridae Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D004854:Herpesvirus 4, Human / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007765:Lacrimal Apparatus / Q000000981:diagnostic imaging / Q000821:virology*; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014412:Tumor Virus Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014764:Viral Proteins / Q000276:immunology
D000956:Antigens, Viral; D036022:Capsid Proteins; C402640:EBNA-LP protein, Human herpesvirus 4; C041788:Epstein-Barr viral capsid antigen; C033305:Epstein-Barr virus early antigen; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D014764:Viral Proteins; D011239:Prednisolone; D002506:Cephalexin