title: Enlargement of mandibular canal without hypesthesia caused by extranodal non-Hodgkin's lymphoma: a case report.
abstract: A rare condition of enlargement of the mandibular canal caused by an extra-nodal non-Hodgkin's lymphoma in a 59-year-old Japanese woman was reported. The patient had a swelling of the hard palate and protrusion of both ocular bulbs, which had been present for 10 years. A panoramic radiograph revealed that the right mandibular canal was widely enlarged, extending from the mandibular foramen to the mental foramen, without bone destruction. The continuous dilation of the mandibular canal to an approximate 15-mm width was associated with peripheral bony sclerosis. Computed tomography and magnetic resonance imaging showed a soft tissue tumor inside the mandibular canal. The lesion demonstrated expansive growth in the orbits, extending to the skull base through the superior orbital fissures and cavernous sinus. The lymphoma was suspected to have grown so slowly that the adjacent mandibular canal and ocular bulbs enlarged without destroying the normal bone and nervous tissue.
authors.affiliation: Department of Dentistry and Oral Surgery and Internal Medicine, Fukui Medical University, Japan. tetsushi@fmsrsa.fukui-med.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Yamada
authors.forename: Y
authors.initials: Y
authors.lastname: Kitagawa
authors.forename: T
authors.initials: T
authors.lastname: Ogasawara
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Ishii
authors.forename: Y
authors.initials: Y
authors.lastname: Urasaki
mesh_terms: D004108:Dilatation, Pathologic / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006987:Hypesthesia; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications*; D016393:Lymphoma, B-Cell / Q000150:complications*; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008334:Mandible / Q000473:pathology*; D008336:Mandibular Diseases / Q000209:etiology*; D008339:Mandibular Neoplasms / Q000150:complications*; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000150:complications; D010026:Osteosclerosis / Q000209:etiology; D011862:Radiography, Panoramic; D019291:Skull Base; D012888:Skull Neoplasms / Q000150:complications; D014057:Tomography, X-Ray Computed