title: [The multifood allergy syndrome].
abstract: Multiple food intolerance in infants and young children is increasingly diagnosed. More than 40% of infants less than 1 y.o. could be affected. The syndrome is characterized by the seriousness of atopic dermatitis (SCORAD > 50), by enterocolitis or failure to thrive or various associations of symptoms that may change over time. The evolution is long-lasting. Common food allergens are milk, egg, soy, wheat, but other ones can be implicated. The diagnosis is established by standardized oral challenges. Multiple etiopathogenic factors are involved: atopy, gastro-enteritis induced intestinal hyperpermeability, precocity of food diversification, breast-feeding continued after the onset of symptoms. Amino-acid based formulas have changed the evolution.
authors.affiliation: Service de Médecine Interne, Immunologie Clinique et Allergologie, Hôpital Central, Nancy.
authors.forename: D A
authors.initials: DA
authors.lastname: Moneret-Vautrin
authors.forename: G
authors.initials: G
authors.lastname: Kanny
authors.forename: L
authors.initials: L
authors.lastname: Guérin
authors.forename: J
authors.initials: J
authors.lastname: Flabbee
authors.forename: P
authors.initials: P
authors.lastname: Lemerdy
mesh_terms: D000485:Allergens / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D003429:Cross Reactions; D003876:Dermatitis, Atopic / Q000209:etiology; D005502:Food / Q000009:adverse effects; D005512:Food Hypersensitivity / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D005759:Gastroenteritis / Q000209:etiology; D006130:Growth Disorders / Q000209:etiology; D006801:Humans; D007223:Infant; D007225:Infant Food / Q000009:adverse effects; D007408:Intestinal Absorption; D013577:Syndrome
chemical_list: D000485:Allergens