Chemotherapy for falciparum malaria: the armoury, the problems and the prospects.
Peter Winstanley here describes the pharmacology and therapeutics of the main drugs used for falciparum malaria in the tropical setting, rather than in the developed world, as an overview for newcomers to the field. He then examines some of the current major problems and prospects for the future.
Winstanley
P A
PA
Department of Pharmacology and Therapeutics, the University of Liverpool, UK L69 3GE. peterwin@liv.ac.uk
D000349:Africa; D000818:Animals; D000962:Antimalarials / Q000009:adverse effects / Q000191:economics / Q000494:pharmacology / Q000627:therapeutic use*; D015195:Drug Design; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy*; D010963:Plasmodium falciparum / Q000187:drug effects*
D000962:Antimalarials