Amperometric biosensors for clinical and therapeutic drug monitoring: a review.
The coupling of enzymes and electrode transducers permits the rapid and simple determination of endogeneous compounds and therapeutic drugs in clinical samples. New developments in the operation, miniaturization and microfabrication of electrochemical biosensors offer exciting possibilities for biomedical and pharmaceutical analysis. This review focuses on the current state of amperometric enzyme electrodes for biomedicine, with emphasis on recent advances, challenges and trends.
Wang
J
J
Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces 88003, USA. joewang@nmsu.edu
D000818:Animals; D015374:Biosensing Techniques; D016903:Drug Monitoring / Q000295:instrumentation*; D004563:Electrochemistry / Q000295:instrumentation*; D006801:Humans