Massive ibuprofen ingestion with survival.
OBJECTIVE
To report a massive, 100 g ibuprofen ingestion in an adolescent, with survival.


METHODS
The patient developed coma, metabolic acidosis, and mild thrombocytopenia, but improved rapidly with supportive care. Renal function remained normal and no gastrointestinal bleeding occurred.


CONCLUSIONS
Massive ingestion of ibuprofen may result in a variable picture with some elements of significant toxicity, but supportive care usually results in survival without sequelae.
Seifert
S A
SA
Rocky Mountain Poison and Drug Center, Denver, Colorado, USA. sseifert@pol.net
Bronstein
A C
AC
McGuire
T
T
D000138:Acidosis / Q000139:chemically induced / Q000628:therapy; D000293:Adolescent; D018712:Analgesics, Non-Narcotic / Q000506:poisoning*; D003128:Coma / Q000139:chemically induced / Q000628:therapy; D062787:Drug Overdose; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000506:poisoning*; D013921:Thrombocytopenia / Q000139:chemically induced / Q000628:therapy
D018712:Analgesics, Non-Narcotic; D007052:Ibuprofen