title: Orbital cholesterol granuloma with destruction of the lateral orbital roof.
abstract: OBJECTIVE
  Orbital cholesterol granuloma in a 51-year-old man is described.
  
  
  METHODS
  Computed tomography (CT) and magnetic resonance imaging (MRI) were done.
  
  
  RESULTS
  Both studies showed a mass in the left orbit, with evidence of orbital roof destruction in the CT scan. On the basis of clinical and imaging findings, a diagnosis was made of malignant orbital tumor with destruction of the lateral orbital roof. Surgical exploration revealed a thickly encapsulated mass densely adherent to the left superior orbital bone and periosteum. Although the dura mater was intact, bone destruction in the lateral orbital roof was seen. The entire mass was successfully excised and histopathological evaluation was performed. Histopathology showed numerous inflammatory cells, blood degradation products, and cholesterol clefts. The absence of epithelial elements led to the diagnosis of cholesterol granuloma.
  
  
  CONCLUSIONS
  Care must be taken to differentiate cholesterol granuloma from malignant orbital tumor. CT scan and MRI imaging seem well-suited to detecting the characteristic findings of cholesterol granuloma.
authors.affiliation: Department of Ophthalmology, Kobe University School of Medicine, Chuo-Ku, Kobe, Japan.
authors.forename: M M
authors.initials: MM
authors.lastname: Karim
authors.forename: M
authors.initials: M
authors.lastname: Inoue
authors.forename: Y
authors.initials: Y
authors.lastname: Hayashi
authors.forename: M
authors.initials: M
authors.lastname: Nishizaki
authors.forename: K
authors.initials: K
authors.lastname: Hanioka
authors.forename: Y
authors.initials: Y
authors.lastname: Imai
authors.forename: H
authors.initials: H
authors.lastname: Ito
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
mesh_terms: D002784:Cholesterol / Q000378:metabolism*; D006099:Granuloma / Q000000981:diagnostic imaging* / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000000981:diagnostic imaging* / Q000473:pathology; D009916:Orbital Diseases / Q000000981:diagnostic imaging* / Q000378:metabolism* / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D002784:Cholesterol