title: A prospective study of computer-aided design and manufacture of titanium plate for cranioplasty and its clinical outcome.
abstract: The use of computerized three dimensional imaging and automated milling of models to produce accurate titanium plates for the reconstruction of craniofacial defects is described. A total of 148 patients have had extensive calvarial defects repaired using this (computer aided design and manufacture) technique developed in our unit. Of these, 141 were repaired secondarily (delayed cranioplasty), whilst seven were repaired immediately following craniectomy (single stage cranioplasty). All cases were assessed for accuracy of fit, restoration of natural skull contour and aesthetics. Seventy-two patients were reviewed after 1 year to determine the effect on adverse preoperative symptoms. Of the plates 97% had an excellent or good intraoperative fit. The modal insertion time was only 15 minutes. Postoperatively 98% resulted in the restoration of natural skull shape and symmetry. After 1 year, 82% of patients had complete resolution or diminution in severity of the adverse symptoms. A staphylococcus infection necessitated the temporary removal of one plate.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Eastman Dental Hospital, UCL Hospitals, London, UK.
authors.forename: J
authors.initials: J
authors.lastname: Joffe
authors.forename: M
authors.initials: M
authors.lastname: Harris
authors.forename: F
authors.initials: F
authors.lastname: Kahugu
authors.forename: S
authors.initials: S
authors.lastname: Nicoll
authors.forename: A
authors.initials: A
authors.lastname: Linney
authors.forename: R
authors.initials: R
authors.lastname: Richards
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001860:Bone Plates; D002648:Child; D017076:Computer-Aided Design; D019465:Craniofacial Abnormalities / Q000601:surgery*; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011446:Prospective Studies; D011474:Prosthesis Design; D014025:Titanium; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014025:Titanium