Temperature-dependent chemical shift and relaxation times of (23)Na in Na(4)HTm[DOTP].
We describe the characterization of a (23)Na temperature-dependent chemical shift and relaxation rates in the complex, Na(4)HTm[DOTP]. This is the first characterization of a (23)Na temperature-dependent chemical shift in a nonmetallic sample. The (23)Na temperature-dependent chemical shift coefficient is approximately -0. 5 PPM/ degrees C for both an aqueous solution and a 6% agarose gel of this compound. This is 50 times the magnitude of the temperature-dependent chemical shift coefficient of water protons. The relaxation times, T(1), T(2f), and T(2s) increased by 0.1, 0.01, and 0.05 ms/ degrees C, respectively. Applications of these unique properties for designing an MRI technique for monitoring heat deposition in tissue and tissue phantoms are discussed.
Shapiro
E M
EM
Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Borthakur
A
A
Bansal
N
N
Leigh
J S
JS
Reddy
R
R
D005782:Gels; D009682:Magnetic Resonance Spectroscopy; D009942:Organometallic Compounds / Q000737:chemistry*; D012975:Sodium Isotopes; D012996:Solutions; D013696:Temperature
D005782:Gels; D009942:Organometallic Compounds; D012975:Sodium Isotopes; D012996:Solutions