A novel HLA-A24 (A*2420) allele identified in the Atayal tribe of Taiwan.
The Taiwan indigenous population groups are classified into different tribes according their linguistic classification and cultural anthropology. One of the tribes, the Atayal, showed a high frequency of A24 alleles by SSOP analysis. High-resolution sequencing based typing identified a A*2402 variant "A*2420" which was found in 6 unrelated individuals. High-resolution typing is required to identify HLA polymorphism in the Taiwanese minority groups.
Scheltinga
S A
SA
University Hospital Utrecht, Section of Molecular and Immunopathology, The Netherlands.
Lai
S M
SM
van der Zwan
A W
AW
Tilanus
M G
MG
Wu
S
S
D000483:Alleles; D001483:Base Sequence; D004247:DNA / Q000032:analysis; D005787:Gene Frequency; D015234:HLA-A Antigens / Q000235:genetics*; D059871:HLA-A24 Antigen; D006801:Humans; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D013624:Taiwan / Q000208:ethnology
D015234:HLA-A Antigens; D059871:HLA-A24 Antigen; D004247:DNA