title: Tropane alkaloids from Erythroxylum zeylanicum O.E. Schulz (Erythroxylaceae).
abstract: Six tropane alkaloids were isolated from the Sri Lankan endemic plant Erythroxylum zeylanicum O.E. Schulz (Erythroxylaceae) and structurally elucidated by NMR and MS measurements. Three of them, erythrozeylanines A [1R,3R,5S,6R-6-acetoxy-3-(3',4',5'-trimethoxybenzoyloxy)tropane], B [cis-3 beta-(cinnamoyloxy)tropane], and C [cis-6 beta-acetoxy-3 alpha-(cinnamoyloxy)tropane] are new, whereas the others have already been found in other Erythroxylum species. For the first time, the absolute configuration of a tropane alkaloid (erythrozeylanine A) has been determined by quantum chemical CD calculations.
authors.affiliation: Institut für Organische Chemie der Universität, Würzburg, Germany. bringman@chemie.uni-wuerzburg.de
authors.forename: G
authors.initials: G
authors.lastname: Bringmann
authors.forename: C
authors.initials: C
authors.lastname: Günther
authors.forename: J
authors.initials: J
authors.lastname: Mühlbacher
authors.forename: M D
authors.initials: MD
authors.lastname: Lalith
authors.forename: P
authors.initials: P
authors.lastname: Gunathilake
authors.forename: A
authors.initials: A
authors.lastname: Wickramasinghe
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010944:Plants / Q000737:chemistry*; D013057:Spectrum Analysis; D014326:Tropanes / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D014326:Tropanes