title: Treatment of severe low back pain with opioids during pregnancy in a patient with incomplete tetraplegia.
abstract: We report a case of severe low back pain during pregnancy in a woman with incomplete tetraplegia due to viral myelitis. The pain was interpreted as a radiculopathy in the presence of multiple herniated discs. Surgical intervention was not indicated and physiotherapy failed; therefore, a symptomatic drug treatment with oral analgesics was initiated. To minimise the total daily opioid dosage and the potential risk of a neonatal withdrawal syndrome due to opioids, the route of administration was changed from oral to epidural. Adequate pain relief was maintained with this regimen until caesarean section was necessary. The neonatal withdrawal symptoms after delivery were mild. Residual pain slowly diminished after delivery and the patient was able to discontinue opioid therapy. The aetiology of low back pain remains unclear and may be multifactorial.
authors.affiliation: Department of Anaesthesiology, University of Cologne, Germany. rainer.sabatowski@uni.koeln.de
authors.forename: R
authors.initials: R
authors.lastname: Sabatowski
authors.forename: L
authors.initials: L
authors.lastname: Radbruch
authors.forename: S
authors.initials: S
authors.lastname: Grond
authors.forename: U J
authors.initials: UJ
authors.lastname: Göhring
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D001416:Back Pain / Q000188:drug therapy*; D005260:Female; D005333:Fetus / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D009020:Morphine / Q000627:therapeutic use*; D009357:Neonatal Abstinence Syndrome / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011782:Quadriplegia / Q000503:physiopathology*
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine