Ethnic differences in genetic susceptibility to atopy and asthma.
The genetics of asthma and atopy is complex, but can be approached by studies of both candidate genes and mapping of susceptibility loci. Genetic factors conferring susceptibility to disease may vary among ethnic groups. We present our experience with some candidate gene studies for asthma and atopy and susceptibility locus mapping for linkage to chromosome 5q.
Tay
A H
AH
Department of Paediatrics, National University of Singapore, Singapore.
Tan
E C
EC
Chew
F T
FT
Goh
D L
DL
Shek
L P
LP
Lee
B W
BW
D044466:Asian People / Q000235:genetics; D001249:Asthma / Q000208:ethnology* / Q000235:genetics; D016207:Cytokines / Q000235:genetics; D020022:Genetic Predisposition to Disease; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000208:ethnology* / Q000235:genetics
D016207:Cytokines