title: Asthma management: evidence based studies and their implications for cost-efficacy.
abstract: This review attempts to infer a cost-effective strategy for the management of bronchial asthma based on evidence from randomized controlled trials. Acute severe asthma should be treated with short-acting inhaled beta-agonists followed by a short course of oral steroids. Decisions on hospital admission should be made within 1 to 2 hours and prolonged treatment in emergency departments avoided. A comprehensive educational and drug optimizing program will prevent chronic illness and relapse. Educational programs should be brief but intensive, supervised by asthma specialists and incorporate self monitoring of symptoms plus written action plans. Peak expiratory flow monitoring should not be mandated for all patients. Inhaled corticosteroids (ICS) are the most cost-effective drugs for the long term prevention of asthma. ICS should be started at low doses. If the symptoms of asthma are not well controlled by moderate doses of ICS, high dose ICS treatment should be avoided and add on medication prescribed instead. Oral bronchodilators are less expensive add on medication than long-acting inhaled beta-agonists.
authors.affiliation: Department of Medicine, National University Hospital, Singapore.
authors.forename: T K
authors.initials: TK
authors.lastname: Lim
mesh_terms: D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000191:economics / Q000628:therapy*; D003362:Cost-Benefit Analysis; D019468:Disease Management; D019317:Evidence-Based Medicine; D006801:Humans; D010353:Patient Education as Topic; D016032:Randomized Controlled Trials as Topic; D055502:Secondary Prevention; D012648:Self Care
chemical_list: D018927:Anti-Asthmatic Agents