[Complications of radiotherapy in patients with age-related macular degeneration (AMD). A study of 48 cases].
OBJECTIVE
This study describes the ocular complications after teletherapy indicated for patients with age-related macular degeneration (AMD).


METHODS
and methods: The study concerned 48 patients suffering from an exudative form of age-related macular degeneration, non suitable for laser photocoagulation, and irradiated by high-energy electron beam therapy.


RESULTS
With a mean follow-up time of 2 years, late effects were observed in 16 (33. 3%) patients: 9 (18.75%) radiation optic neuropathies, 9 radiation retinopathies (18.75%) and 2 neovascular glaucomas (4.1%).


CONCLUSIONS
The frequent and serious complications observed led us to adapt the technique and dose of radiation therapy indicated in patients with age-related macular degeneration.
Valanconny
C
C
Service d'Ophtalmologie, Hôpital Bellevue, CHU Saint-Etienne, 42055 Saint-Etienne Cedex 2.
Koenig
F
F
Benchaboune
M
M
Goyet
D
D
Mezmate
K
K
Schmitt
T
T
Maugery
J
J
D000368:Aged; D000369:Aged, 80 and over; D004583:Electrons; D005123:Eye / Q000528:radiation effects*; D005260:Female; D005500:Follow-Up Studies; D015355:Glaucoma, Neovascular / Q000209:etiology; D006801:Humans; D008268:Macular Degeneration / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000209:etiology; D011832:Radiation Injuries / Q000209:etiology*; D011882:Radiotherapy, High-Energy; D012164:Retinal Diseases / Q000209:etiology; D014792:Visual Acuity / Q000528:radiation effects