[The importance of fluid perfusion for the outcome of the disease in malarial coma due to Plasmodium falciparum in adult Africans].
Malaria coma induced by P.falciparum was diagnosed in 51 of 390 adult African patients who had been admitted to the therapeutical unit of the Donk Central Hospital and were receiving parenteral quinine at day 1 of the onset of coma. Examining some clinical and laboratory manifestations of malaria coma indicated that fatal outcome was significantly recorded among the patients with severe concomitant anemia and among the patients who had not or had received inadequate liquid parenterally on the first day of coma. The occurrence of acute renal failure in 4 patients with malaria coma resulted in 3 deaths. No great impact on the prognosis of malaria "hyperparasitemia", the severity of fever, the values of blood pressure was found. Whether it is advisable to use the parameters characterizing the opportuneness and scope of health care delivered to patients with severe malaria is discussed.
Severov
M V
MV
Sank Diallo
A A
AA
Magassouba
N F
NF
Cherif Baldé
A M
AM
Barry
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003128:Coma / Q000209:etiology / Q000628:therapy*; D003681:Dehydration / Q000209:etiology / Q000628:therapy; D005260:Female; D005440:Fluid Therapy / Q000706:statistics & numerical data; D016701:Guinea; D006801:Humans; D016778:Malaria, Falciparum / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D018512:Parasitemia / Q000150:complications / Q000628:therapy; D011379:Prognosis; D016896:Treatment Outcome