title: Developmental defects and chromosomal aberrations in spontaneous abortions and stillbirths.
abstract: The authors analysed 1488 cases of spontaneous abortions and stillbirths in Bratislava. They focused on the course of human embryogenesis and the chromosomal constitution. A high mean frequency rate of both developmental defects (14.4%) and chromosomal aberrations (33.6%) was revealed and both were found to be in close relation with the length of gestation. The most severe developmental defects occurred mostly in early stages of human embryogenesis, i.e. in the 1st trimester of gestation.
authors.affiliation: Institute of Medical Biology, School of Medicine, Comenius University, Bratislava, Slovakia. vojtassak@medik.fmed.uniba.sk
authors.forename: J
authors.initials: J
authors.lastname: Vojtassák
authors.forename: J
authors.initials: J
authors.lastname: Malová
authors.forename: L
authors.initials: L
authors.lastname: Demjenová
authors.forename: P
authors.initials: P
authors.lastname: Martanovic
authors.forename: D
authors.initials: D
authors.lastname: Böhmer
authors.forename: M
authors.initials: M
authors.lastname: Korbel
authors.forename: L
authors.initials: L
authors.lastname: Danihel
authors.forename: P
authors.initials: P
authors.lastname: Fiala
authors.forename: M
authors.initials: M
authors.lastname: Duríková
authors.forename: T
authors.initials: T
authors.lastname: Braxatorisová
authors.forename: V
authors.initials: V
authors.lastname: Geislerová
authors.forename: E
authors.initials: E
authors.lastname: Pagácová
mesh_terms: D000022:Abortion, Spontaneous / Q000235:genetics*; D002869:Chromosome Aberrations; D000013:Congenital Abnormalities / Q000235:genetics*; D005314:Embryonic and Fetal Development; D005260:Female; D005313:Fetal Death / Q000235:genetics*; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D018154:Slovakia