Retroperitoneoscopic excision of phaeochromocytoma--haemodynamic events, complications and outcome.
Over a period of 15 months, 11 patients with phaeochromocytoma underwent retroperitoneoscopic excision of their tumours. Five patients had bilateral tumours. All patients underwent thorough preoperative evaluation and preparation with alpha- and beta-blockade. In the majority of the patients a hypertensive response was seen during generation of pneumoretroperitoneum. However, the period of tumour dissection and excision was devoid of large haemodynamic fluctuations. The average time taken was 3.5 to 4 hours per gland. Blood loss in successful laparoscopic excision averaged 240 ml (range 120 to 700 ml). In these patients satisfactory postoperative analgesia could be provided with intramuscular pethidine or intramuscular diclofenac sodium. In three patients the procedure had to be converted to open laparotomy due to haemorrhage. All three patients had preoperative radiological evidence of inferior vena cava and aortic involvement. Patient selection plays an important role in a successful outcome.
Subramaniam
R
R
Department of Anaesthesiology and Intensive Care, All India Institute of Medical Sciences, New Delhi, India.
Pandit
B
B
Sadhasivam
S
S
Sridevi
K B
KB
Kaul
H L
HL
D000310:Adrenal Gland Neoplasms / Q000601:surgery*; D000315:Adrenalectomy / Q000379:methods*; D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D016063:Blood Loss, Surgical; D001810:Blood Volume; D004008:Diclofenac / Q000008:administration & dosage; D005260:Female; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007430:Intraoperative Care; D007431:Intraoperative Complications / Q000209:etiology; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008614:Meperidine / Q000008:administration & dosage; D010149:Postoperative Pain / Q000188:drug therapy; D018579:Patient Selection; D010673:Pheochromocytoma / Q000601:surgery*; D012187:Retroperitoneal Space; D013997:Time Factors; D016896:Treatment Outcome
D000701:Analgesics, Opioid; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac; D008614:Meperidine