title: Improving image quality and T(1) measurements using saturation recovery turboFLASH with an approximate K-space normalisation filter.
abstract: We present a method for reducing the image point-spread function and measuring T(1) using saturation recovery turboFLASH (SRTF) with centric-ordered k-space and a k-space correction filter designed to compensate for longitudinal magnetisation evolution during image acquisition. The method provides a two point T(1) measurement that reduces inaccuracies and image artefacts caused by longitudinal magnetisation evolution in conventional turboFLASH methods. The method is designed for use in rapid, quantitative measurements of contrast agent uptake in vivo.
authors.affiliation: Cancer Research Campaign Clinical Magnetic Resonance Research Group, Institute of Cancer Research and Royal Marsden NHS Trust, Downs Road, Sutton, Surrey, UK.
authors.forename: G J
authors.initials: GJ
authors.lastname: Parker
authors.forename: I
authors.initials: I
authors.lastname: Baustert
authors.forename: S F
authors.initials: SF
authors.lastname: Tanner
authors.forename: M O
authors.initials: MO
authors.lastname: Leach
mesh_terms: D000328:Adult; D003287:Contrast Media; D005583:Fourier Analysis; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation*; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008297:Male; D010388:Pelvis / Q000033:anatomy & histology; D019047:Phantoms, Imaging; D012016:Reference Values
chemical_list: D003287:Contrast Media