The cancer anorexia-cachexia syndrome.
The cancer anorexia-cachexia syndrome is one of the most common causes of death among cancer patients and is present in 80% at death. It is a complex example of metabolic chaos effecting protein, carbohydrate, and fat metabolism. Tumors produce both direct and indirect abnormalities, resulting in anorexia and weight loss. The disease burden does not correlate with the degree of cachexia. Although there is no treatment to control or reverse the process, appetite stimulants may promote increased food intake and enhance quality of life.
Nelson
K A
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Harry R. Horvitz Center for Palliative Medicine, and the Taussig Cancer Center, The Cleveland Clinic Foundation, OH 44195, USA.
D002100:Cachexia / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D009369:Neoplasms / Q000150:complications* / Q000628:therapy; D010166:Palliative Care; D019282:Wasting Syndrome / Q000188:drug therapy* / Q000209:etiology*