On-line ion-pair solid-phase extraction-liquid chromatography-mass spectrometry for the analysis of quaternary ammonium herbicides.
An ion-pair on-line solid-phase extraction procedure using C8 extraction disks, suitable for liquid chromatography-mass spectrometry analysis is developed to determine quaternary ammonium herbicides (quats) in water samples. The separation of these compounds was performed using ion-pair chromatography with heptafluorobutyric acid (15 mM, pH 3.3) and acetonitrile gradient elution. Detection was carried out using a quadrupole mass spectrometer. Water sample volumes up to 50 ml can be preconcentrated with recoveries higher than 70%. Good precision and accuracy (day-to-day and run-to-run) were obtained and the detection limits ranged from 6 to 85 ng l(-1). The proposed on-line ion-pair solid-phase method enables compliance with European Community directives for drinking waters (100 ng l(-1)).
Castro
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R
Departament Química Analítica, Universitat de Barcelona, Spain.
Moyano
E
E
Galceran
M T
MT
D002853:Chromatography, Liquid / Q000379:methods*; D004563:Electrochemistry; D006540:Herbicides / Q000032:analysis*; D007477:Ions; D013058:Mass Spectrometry; D000644:Quaternary Ammonium Compounds / Q000032:analysis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D006540:Herbicides; D007477:Ions; D000644:Quaternary Ammonium Compounds