Ecdysteroids from the caribbean sponge Iotrochota birotulata.
The sterol composition of the Caribbean sponge Iotrochota birotulata was investigated. Structure of a new ecdysteroid 2beta,3beta,14alpha, 20beta-tetrahydroxy-22alpha-(2-hydroxyacetiloxy)-5b eta-colest-7-en-6- one (1) was assigned on the basis of spectroscopic and chemical evidence and molecular mechanics calculations. Isolation of the widespread ecdysteroids 2-5 is also reported.
Costantino
V
V
Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli "Federico II," Via D. Montesano 49, 80131, Naples, Italy.
Dell'Aversano
C
C
Fattorusso
E
E
Mangoni
A
A
D000818:Animals; D017691:Caribbean Region; D002783:Cholestenones / Q000737:chemistry* / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013256:Steroids / Q000737:chemistry* / Q000302:isolation & purification*
C406713:2,3,14,20-tetrahydroxy-22-(2-hydroxyacetyloxy)cholest-7-en-6-one; D002783:Cholestenones; D013256:Steroids