title: New paralytic alkaloids, asperparalines A, B and C, from Aspergillus japonicus JV-23.
abstract: New paralytic alkaloids, asperparalines A (1), B (2) and C (3), were isolated from okara (the insoluble residue of whole soybean) that had been fermented with Aspergillus japonicus JV-23. Their structures were elucidated by spectroscopic methods and X-ray crystallography. These asperparalines showed paralytic activity against silk worms.
authors.affiliation: Department of Applied Biological Chemistry, College of Agriculture, Osaka Prefecture University, Japan. hayashi@biochem.osakafu-u.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Hayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Nishimoto
authors.forename: K
authors.initials: K
authors.lastname: Akiyama
authors.forename: H
authors.initials: H
authors.lastname: Nozaki
mesh_terms: D000470:Alkaloids / Q000032:analysis*; D000818:Animals; D001230:Aspergillus / Q000737:chemistry*; D012831:Bombyx / Q000187:drug effects; D018360:Crystallography, X-Ray; D005285:Fermentation; D007814:Larva / Q000187:drug effects; D008956:Models, Chemical; D008958:Models, Molecular; D010243:Paralysis / Q000139:chemically induced; D010879:Piperazines; D011487:Protein Conformation; D013025:Glycine max; D013141:Spiro Compounds
chemical_list: D000470:Alkaloids; D010879:Piperazines; D013141:Spiro Compounds; C109708:aspergillimide; C406331:asperparaline B; C406332:asperparaline C