title: Prenatal diagnosis and outcome in sacrococcygeal teratomas: a review of cases between 1992 and 1998.
abstract: A review of sacrococcygeal teratomas diagnosed in the antenatal period in the West Midlands region over a six year interval is reported. The aim of the study was to assess the contribution of ultrasound scanning to the management of cases and to determine the outcome of prenatally diagnosed sacrococcygeal teratomas. A retrospective review of 10 cases was performed to obtain pregnancy details, ultrasound scan data and outcome information. Two fetuses were electively aborted. Perinatal mortality was 62.5% in the remaining cases with all stillbirths and neonatal deaths occurring in babies delivered preterm (at or before 34 weeks' gestation). Marked increase in tumour size (mainly vascular/solid) was observed in five of the fetuses, which was often associated with local compression effects and the development of hydrops. Eight out of 10 cases were delivered vaginally, one following aspiration of the large cystic tumour. Three of the four neonates surviving to surgery underwent successful resection of their benign tumours. As well as guiding prognosis, serial ultrasound scans may also allow the mode of delivery to be planned more effectively. The importance of a multidisciplinary team approach to these difficult cases is emphasized.
authors.affiliation: Academic Department of Obstetrics & Gynaecology, Birmingham Women's Hospital, Edgbaston, Birmingham, UK.
authors.forename: V
authors.initials: V
authors.lastname: Brace
authors.forename: S R
authors.initials: SR
authors.lastname: Grant
authors.forename: K J
authors.initials: KJ
authors.lastname: Brackley
authors.forename: M D
authors.initials: MD
authors.lastname: Kilby
authors.forename: M J
authors.initials: MJ
authors.lastname: Whittle
mesh_terms: D000028:Abortion, Induced; D000293:Adolescent; D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000401:mortality; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D012445:Sacrococcygeal Region; D013724:Teratoma / Q000000981:diagnostic imaging* / Q000401:mortality / Q000601:surgery; D016216:Ultrasonography, Prenatal