title: Regulation of the ketogenic enzyme mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in astrocytes and meningeal fibroblasts. Implications in normal brain development and seizure neuropathologies.
authors.affiliation: Department of Neurochemistry, Institute of Neurology, London, U.K.
authors.forename: T E
authors.initials: TE
authors.lastname: Cullingford
authors.forename: K K
authors.initials: KK
authors.lastname: Bhakoo
authors.forename: S
authors.initials: S
authors.lastname: Peuchen
authors.forename: C T
authors.initials: CT
authors.lastname: Dolphin
authors.forename: J B
authors.initials: JB
authors.lastname: Clark
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000201:enzymology*; D001921:Brain / Q000201:enzymology* / Q000254:growth & development; D004268:DNA-Binding Proteins / Q000378:metabolism; D005347:Fibroblasts / Q000201:enzymology; D015971:Gene Expression Regulation, Enzymologic; D006801:Humans; D006904:Hydroxymethylglutaryl-CoA Synthase / Q000235:genetics* / Q000378:metabolism*; D008578:Meninges / Q000201:enzymology*; D008928:Mitochondria / Q000201:enzymology*; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism; D012640:Seizures / Q000201:enzymology* / Q000503:physiopathology; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D004268:DNA-Binding Proteins; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors; D006904:Hydroxymethylglutaryl-CoA Synthase