title: Healthy adults demonstrate less skin reactivity to commercial extracts of commonly ingested food than to D. farinae.
abstract: The aim of this study is to determine the skin reactivity of healthy Oriental adults to commercial extracts of commonly ingested food and the house dust mite D. farinae, a common local aeroallergen. D. farinae and 18 food extracts were skin prick tested on adults without any personal history of atopic diseases and food allergy. The extracts of food not consumed by any subject on religious or personal grounds were not tested for that individual. A total of 103 healthy adults who fulfilled the selection criteria were skin prick tested. There were 35 males and 68 females. Their mean age was 29 years (SD +/- 7.5) with a range of 19 to 49 years. Sixty-eight percent were Chinese, 12.6% Malay, 12.6% Indian and 6.8% other Oriental races. Fifty-four (52.4%) were positive for D. farinae while only 12 (11.7%) were positive for at least one food extract The food extract that gave the most number of positive reactions was shellfish mix (5/102, 4.9%). A family history of atopy did not have any significant correlation with the results of skin test. It was concluded that healthy adults demonstrate less skin reactivity to extracts of commonly ingested food than to D. farinae.
authors.affiliation: Department of Rheumatology & Immunology, Tan Tock Seng Hospital, Singapore.
authors.forename: H H
authors.initials: HH
authors.lastname: Chng
authors.forename: C Y
authors.initials: CY
authors.lastname: Tang
authors.forename: K P
authors.initials: KP
authors.lastname: Leong
mesh_terms: D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000276:immunology; D000818:Animals; D039741:Antigens, Dermatophagoides; D004391:Dust; D005260:Female; D005502:Food / Q000009:adverse effects*; D005511:Food Handling; D005512:Food Hypersensitivity / Q000276:immunology*; D006023:Glycoproteins / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008925:Mites / Q000276:immunology*; D012846:Singapore; D012882:Skin Tests
chemical_list: D000485:Allergens; D039741:Antigens, Dermatophagoides; D004391:Dust; D006023:Glycoproteins