title: Soft tissue sarcomas: ultrasonographic evaluation of local recurrences.
abstract: OBJECTIVE
  The diagnosis of early local recurrence of soft tissue sarcomas, especially in those treated with surgery and radiotherapy, is a difficult clinical problem. Financial constraints led us to use ultrasonography instead of CT or MR imaging. The aim of this study was to evaluate the role of ultrasonography (US) in detecting local recurrence.
  
  
  RESULTS
  Fifty patients with previous treatment for soft tissue sarcomas were evaluated prospectively for recurrence by US and histopathology. Seven of the 50 patients were clinically suspected to have recurrent tumour. Ultrasonography showed recurrence in 26, no recurrence in 18, benign disease in four and was indeterminate in two cases. Ultrasonography was instrumental in guiding fine needle aspiration biopsies of small local recurrences and indeterminate lesions in 17 patients. In the sonographically tumour positive patients, histopathology confirmed recurrence in 24; one case had benign disease and one patient refused surgery. Thirteen of the 18 sonographically tumour negative patients were operated upon; all were negative for tumour on histopathology. Both the indeterminate cases showed recurrence on histopathology. The benign cases were confirmed by histopathology correlation. Ultrasound guided fine needle aspiration cytology (FNAC) was positive in 14 out of 17 patients (88%). The sensitivity and specificity of US was 92.30% and 94.4% respectively.
  
  
  CONCLUSIONS
  Our study concludes that US is an extremely useful and cost effective method in the detection of early local recurrences of soft tissue sarcomas and should therefore be used for initial routine follow-up and guided biopsies.
authors.affiliation: Department of Diagnostic Radiology, Tata Memorial Hospital, Parel, Mumbai 400 012, India.
authors.forename: S
authors.initials: S
authors.lastname: Arya
authors.forename: D G
authors.initials: DG
authors.lastname: Nagarkatti
authors.forename: S B
authors.initials: SB
authors.lastname: Dudhat
authors.forename: K S
authors.initials: KS
authors.lastname: Nadkarni
authors.forename: M S
authors.initials: MS
authors.lastname: Joshi
authors.forename: S R
authors.initials: SR
authors.lastname: Shinde
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D011446:Prospective Studies; D012509:Sarcoma / Q000000981:diagnostic imaging*; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging*; D014463:Ultrasonography