title: Haematocin, a new antifungal diketopiperazine produced by Nectria haematococca Berk. et Br. (880701a-1) causing nectria blight disease on ornamental plants.
abstract: A new antifungal diketopiperazine named haematocin was isolated from the culture broth of Nectria haematococca Berk. et Br. (880701a-1) causing blight disease on ornamental plants, Phalaenopsis spp. and Doritanopsis spp. Its structure was established by spectroscopic methods. Haematocin inhibited the germ-tube elongation and spore-germination of Pyricularia oryzae at the ED50 values of 30 microg/ml and 160 microg/ml, respectively.
authors.affiliation: The Institute of Physical and Chemical Research (RIKEN), Wako-shi, Saitama, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
authors.forename: Y
authors.initials: Y
authors.lastname: Esumi
authors.forename: T
authors.initials: T
authors.lastname: Arie
authors.forename: T
authors.initials: T
authors.lastname: Morita
authors.forename: H
authors.initials: H
authors.lastname: Koshino
authors.forename: J
authors.initials: J
authors.lastname: Uzawa
authors.forename: M
authors.initials: M
authors.lastname: Uramoto
authors.forename: I
authors.initials: I
authors.lastname: Yamaguchi
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry; D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D007211:Indoles / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D010082:Oxepins / Q000737:chemistry; D010879:Piperazines / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014675:Vegetables / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D007211:Indoles; D010082:Oxepins; D010879:Piperazines; C406046:haematocin; C006370:acetylaranotin