title: Benign partial epilepsy in infancy and early childhood with vertex spikes and waves during sleep: a new epileptic form.
abstract: International epilepsy classification includes different epileptic syndromes with favourable outcomes in paediatric age, both partial and generalised. This is true in childhood while no partial benign forms are accepted in infancy. In 1987, Watanabe first described a new entity and he defined it as 'benign complex partial epilepsies in infancy'. In 1992, Vigevano referred similar but familial cases whose seizures had secondary generalisation. Both these forms had no interictal EEG abnormalities neither awake nor during sleep. This article presents a survey of 12 cases of partial epilepsy with favourable outcome differing from Watanabe and Vigevano's cases, both for the presence of interictal EEG abnormalities only during sleep and for seizure picture. All our patients are neurologically and neuroradiologically normal. Psychomotor development is unremarkable. Age onset range is 13-30 months. All cases present characteristic spikes and waves during slow-sleep in vertex cerebral areas. Awake EEG is always normal, at follow-up too. Our cases have such homogeneous electroclinical features as to hypothesise a new partial idiopathic epileptic syndrome with favourable outcome in infancy and early childhood. We propose to define it as 'benign partial epilepsy in infancy and early childhood with vertex spikes and waves' (BVSE).
authors.affiliation: Department of Child Neuropsychiatry, C. Poma Hospital, Mantova, Italy. pcapovil@mbox.mynet.it
authors.forename: G
authors.initials: G
authors.lastname: Capovilla
authors.forename: F
authors.initials: F
authors.lastname: Beccaria
mesh_terms: D002648:Child; D002675:Child, Preschool; D004828:Epilepsies, Partial / Q000503:physiopathology*; D020936:Epilepsy, Benign Neonatal / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D012890:Sleep / Q000502:physiology*