Isolation and cultivation of lung epithelial type 2 cells. The effect of cadmium.
The effects of cadmium exposure on rat lung type 2 cells were evaluated by morphological and biochemical examinations. The results showed dose dependent reduction in the marker enzyme (alkaline phosphatase), changes in cell membranes and in the antioxidant status.
Kováciková
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Institute of Preventive and Clinical Medicine, Bratislava, Slovakia. kovacik@upkm.sk
Tátrai
E
E
D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D019256:Cadmium Chloride / Q000633:toxicity*; D018929:Cell Culture Techniques / Q000379:methods; D002462:Cell Membrane / Q000187:drug effects / Q000648:ultrastructure; D002478:Cells, Cultured; D004847:Epithelial Cells / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D008168:Lung / Q000166:cytology*; D008297:Male; D015388:Organelles / Q000187:drug effects / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar
D000975:Antioxidants; D000469:Alkaline Phosphatase; D005978:Glutathione; D019256:Cadmium Chloride