title: Magnetic resonance imaging of intestinal necrosis in preterm infants.
abstract: OBJECTIVE
  Noninvasive diagnosis of intestinal necrosis is important in planning surgery in preterm infants with necrotizing enterocolitis (NEC). We aimed to assess the potential of magnetic resonance imaging (MRI) for the diagnosis of intestinal necrosis.
  
  
  METHODS
  Abdominal MRI scans were performed in a group of preterm infants with suspected NEC and compared with surgical findings and to MRI results in a group of control infants. In addition, MRI was performed in 2 preterm infants with suspected NEC who did not require surgery.
  
  
  RESULTS
  Six infants with a median birth weight of 1220 g (range, 760-1770 g) and median gestational age at birth of 30 weeks (range, 28-34 weeks) were studied at a median postnatal age of 10 days (range, 4-19 days). Four infants had a bubble-like appearance in part of the intestinal wall, intramural gas, and an abnormal fluid level within bowel lumen. At surgery, NEC was found in 5 infants and sigmoid volvulus in 1. The site of the bubble-like appearance corresponded to the site of intestinal necrosis at surgery. Four control infants with a median birth weight of 1500 g (range, 730-2130 g) and a median gestational age of 31 weeks (range, 26-36 weeks) had abdominal MRI at a median postnatal age of 8 days (range, 4-70 days). None of the above findings were seen in any control infant. The bubble-like appearance was not seen in the 2 infants with suspected NEC who did not require surgery.
  
  
  CONCLUSIONS
  Abdominal MRI allows the noninvasive diagnosis of bowel necrosis. This may aid the timing of surgical intervention in preterm infants with a clinical diagnosis of NEC.gangrene, ischemia, MRI, necrotizing enterocolitis.
authors.affiliation: Department of Paediatrics, Imperial College School of Medicine, Hammersmith Hospital, London, England.
authors.forename: E F
authors.initials: EF
authors.lastname: Maalouf
authors.forename: A
authors.initials: A
authors.lastname: Fagbemi
authors.forename: P J
authors.initials: PJ
authors.lastname: Duggan
authors.forename: S
authors.initials: S
authors.lastname: Jayanthi
authors.forename: S J
authors.initials: SJ
authors.lastname: Counsell
authors.forename: H J
authors.initials: HJ
authors.lastname: Lewis
authors.forename: A M
authors.initials: AM
authors.lastname: Fletcher
authors.forename: K
authors.initials: K
authors.lastname: Lakhoo
authors.forename: A D
authors.initials: AD
authors.lastname: Edwards
mesh_terms: D001724:Birth Weight; D003106:Colon / Q000473:pathology; D020345:Enterocolitis, Necrotizing / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D010347:Patient Care Planning; D012307:Risk Factors; D012680:Sensitivity and Specificity