[Acute toxicity of 10 Moroccan plants reported to be hypoglycemic agents].
An acute toxicity study of twelve medicinal plants on Swiss albino mice has been carried out. The extracts were administered orally at a dose of 1 g/kg body weight. Animals were observed for 7 days and changes in weight and behaviour were noted. On the eighth day, the animals were sacrificed and an anatomo-histopathologic survey was undertaken. The results showed a change in behaviour and some histologic modifications following the administration of certain plant extracts.
Jaouhari
J T
JT
Département de Biologie, Ecole Normale Supérieure, Marrakech, Maroc.
Lazrek
H B
HB
Jana
M
M
D000284:Administration, Oral; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D005260:Female; D007004:Hypoglycemic Agents / Q000633:toxicity*; D007413:Intestinal Mucosa / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008168:Lung / Q000187:drug effects; D008297:Male; D051379:Mice; D009018:Morocco; D010179:Pancreas / Q000187:drug effects; D010936:Plant Extracts / Q000633:toxicity*; D010946:Plants, Medicinal / Q000633:toxicity*; D013662:Tea
D007004:Hypoglycemic Agents; D010936:Plant Extracts; D013662:Tea