title: Tuberculosis and Pelger-Huët anomaly. Case report.
abstract: We describe a patient with pulmonary tuberculosis and a rare disturbance of leukocyte segmentation, known as "Pelger-Huët anomaly", which can be observed in various diseases such as malignancies and/or infections. The importance of this association is equivocal: some authors have related to the association the particular severity of tuberculosis or the death they observed; in the case reported we noted no evidence of such a relation, notwithstanding the presence of the homozygous form of the Pelger-Huët anomaly. We suggest therefore that, when Pelger-Huët anomaly is found, an underlying disease should be searched for; the course of this illness, however, might not be affected.
authors.affiliation: Division of Pneumophtisiology, Clinical Laboratory, E. Morelli Hospital, Sondalo, SO, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Cicchitto
authors.forename: M
authors.initials: M
authors.lastname: Parravicini
authors.forename: S
authors.initials: S
authors.lastname: De Lorenzo
authors.forename: G
authors.initials: G
authors.lastname: Di Pisa
authors.forename: A
authors.initials: A
authors.lastname: Malacrida
mesh_terms: D000328:Adult; D005260:Female; D006098:Granulocytes / Q000473:pathology; D006720:Homozygote; D006801:Humans; D010381:Pelger-Huet Anomaly / Q000150:complications* / Q000235:genetics / Q000473:pathology; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000473:pathology