title: Reconstruction and visualization of irregularly sampled three- and four-dimensional ultrasound data for cerebrovascular applications.
abstract: Although recent studies have demonstrated the potential value of compounded data for improvement in signal-to-noise ratio and speckle contrast for three-dimensional (3-D) ultrasonography, clinical applications are lacking. We investigated the potential of six degrees-of-freedom (6-DOF) scanhead position and orientation measurement (POM) devices for registration of in vivo multiplanar, irregularly sampled ultrasound (US) images to a regular 3-D volume space. The results demonstrate that accurate spatial and temporal registration of four-dimensional (4-D) US data can be achieved using a 6-DOF scanhead tracking system. For reconstruction of arbitrary, irregularly sampled US data, we introduce a technique based upon a weighted, ellipsoid Gaussian convolution kernel. Volume renderings of 3-D and 4-D compounded in vivo US data are presented. The results, although restricted to the field of cerebrovascular disease, will be of value to other applications of 3-D sonography, particularly those in which compounding of data through irregular sampling may provide superior information on tissue or vessel structure.
authors.affiliation: Department of Neurology, University of Heidelberg, Klinikum Mannheim, Mannheim, Germany. meairs@neuro.ma.uni-heidelberg.de
authors.forename: S
authors.initials: S
authors.lastname: Meairs
authors.forename: J
authors.initials: J
authors.lastname: Beyer
authors.forename: M
authors.initials: M
authors.lastname: Hennerici
mesh_terms: D001783:Blood Flow Velocity; D002339:Carotid Arteries / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002536:Cerebral Arteries / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D015203:Reproducibility of Results; D018615:Ultrasonography, Doppler, Color; D017585:Ultrasonography, Doppler, Transcranial