Minimal change glomerulonephritis associated with hydatid disease.
A 63-year-old man presented to our department with dyspnea and peripheral edema. A cystic mass in the right upper abdomen, consistent with echinococcal disease was discovered. Proteinuria was also present, and a nephrotic syndrome was diagnosed. The kidney biopsy revealed minimal change glomerulonephritis. Treatment with the antiechinococcal drug albendazole induced complete remission of the nephrotic syndrome, suggesting an etiopathogenic role for a hydatid antigen in the development of an immune-mediated glomerulonephritis.
Gelman
R
R
Department of Internal Medicine D, Rambam Medical Center, Rappaport Institute, Faculty of Medicine, Haifa, Israel.
Brook
G
G
Green
J
J
Ben-Itzhak
O
O
Nakhoul
F
F
D015766:Albendazole / Q000008:administration & dosage; D000923:Anticestodal Agents / Q000008:administration & dosage; D001706:Biopsy; D004444:Echinococcosis, Hepatic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007159:Immunologic Tests; D007668:Kidney / Q000473:pathology; D008099:Liver / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009402:Nephrosis, Lipoid / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D009404:Nephrotic Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D011877:Radionuclide Imaging; D014463:Ultrasonography
D000923:Anticestodal Agents; D015766:Albendazole