title: Deliberate self-poisoning in adolescence: why does a brief family intervention work in some cases and not others?
abstract: In a randomized trial of a brief family intervention with adolescents who had deliberately poisoned themselves, we have previously reported that, within the group of patients who did not have major depression, the family intervention was significantly superior to routine care in reducing suicidal thinking. The present paper examined whether efficacy was related to changes in family functioning or other possible mediating variables. Potential mediators included family functioning, hopelessness, depression, adolescent problem-solving and compliance with treatment. The efficacy of the family intervention in reducing suicidal ideation within the non-depressed sub-group was probably not mediated by changes in these variables. The implications of this finding are discussed.
authors.affiliation: Department of Child and Adolescent Psychiatry, Royal Manchester Children's Hospital, Manchester, UK.
authors.forename: R
authors.initials: R
authors.lastname: Harrington
authors.forename: M
authors.initials: M
authors.lastname: Kerfoot
authors.forename: E
authors.initials: E
authors.lastname: Dyer
authors.forename: F
authors.initials: F
authors.lastname: Mcniven
authors.forename: J
authors.initials: J
authors.lastname: Gill
authors.forename: V
authors.initials: V
authors.lastname: Harrington
authors.forename: A
authors.initials: A
authors.lastname: Woodham
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior / Q000523:psychology*; D003863:Depression / Q000523:psychology / Q000628:therapy; D005196:Family Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D011041:Poisoning; D016032:Randomized Controlled Trials as Topic; D013406:Suicide, Attempted / Q000517:prevention & control*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome