title: Application of spectral libraries for high-performance liquid chromatography-atmospheric pressure ionisation mass spectrometry to the analysis of pesticide and explosive residues in environmental samples.
abstract: The coupling of high-performance liquid chromatography (HPLC) and atmospheric pressure ionisation mass spectrometry (API-MS) seems to be the method of choice if good separation and selective detection of semi-volatile, thermolabile, and polar substances is required. Libraries of mass spectra will make the identification of unknown substances in complex environmental samples easier and more user-friendly. Unfortunately, existing GC-MS libraries are not applicable to HPLC-API-MS analysis. Thus, new and extensive mass spectral libraries were constructed. Several investigations of chromatographic (composition and salt concentration of the eluent) as well as mass spectrometric (orifice voltage) parameters and a few applications of real environmental samples are used to discuss the possibilities and limits of these libraries.
authors.affiliation: Universität Leipzig, Institut für Analytische Chemie, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Schreiber
authors.forename: J
authors.initials: J
authors.lastname: Efer
authors.forename: W
authors.initials: W
authors.lastname: Engewald
mesh_terms: D001274:Atmospheric Pressure; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004785:Environmental Pollutants / Q000032:analysis*; D005107:Explosions; D013058:Mass Spectrometry / Q000379:methods*; D010573:Pesticide Residues / Q000032:analysis*
chemical_list: D004785:Environmental Pollutants; D010573:Pesticide Residues