Detection of four novel alleles: DRB1*1130, DRB1*13072, DRB1*1315 and DRB1*1331.
Four new DR52-associated DRB1 alleles are described. One allele, DRB1*1130, is a hybrid between a DRB3*02 allele and a DRB1*11011 allele. The other alleles, DRB1*13072, DRB1*1315, and DRB1*1331, are simple reshufflings of known polymorphic motifs.
Lin
Y S
YS
Department of Pediatrics, Georgetown University Medical Center, Washington, DC 20007, USA.
Hoyer
R J
RJ
Tang
T F
TF
Ng
J
J
Hartzmann
R J
RJ
Hurley
C K
CK
D000483:Alleles; D001483:Base Sequence; D017931:DNA Primers / Q000737:chemistry; D005785:Gene Conversion; D006684:HLA-DR Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains; D006801:Humans; D008969:Molecular Sequence Data; D044469:Racial Groups / Q000235:genetics; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid
D017931:DNA Primers; D006684:HLA-DR Antigens; D059811:HLA-DRB1 Chains; C553518:HLA-DRB1*11:01:01 antigen