HOE 077 reduces fibrotic overgrowth around the barium alginate microcapsules.
Zhang
W J
WJ
Institute of Physiology and Biochemistry, Federal Research Centre, Kiel, Germany.
Marx
S K
SK
Laue
C
C
Hyder
A
A
Juergensen
A
A
Bickel
M
M
Schrezenmeir
J
J
D000464:Alginates / Q000633:toxicity*; D000818:Animals; D001464:Barium; D002214:Capsules / Q000009:adverse effects*; D002469:Cell Separation; D002470:Cell Survival / Q000187:drug effects; D005355:Fibrosis; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism; D016381:Islets of Langerhans Transplantation / Q000473:pathology / Q000502:physiology*; D008099:Liver / Q000187:drug effects / Q000473:pathology*; D008106:Liver Cirrhosis, Experimental / Q000517:prevention & control*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D011355:Prodrugs / Q000494:pharmacology; D011725:Pyridines / Q000494:pharmacology*; D013552:Swine; D016042:Transplantation, Heterotopic
D000464:Alginates; D002214:Capsules; D007328:Insulin; D011355:Prodrugs; D011725:Pyridines; D001464:Barium; C074630:lufironil