[Relationship between fatty liver and coronary risk factors].
Fatty liver is a common finding in abdominal ultrasonographic examination in health check-ups, but the relationship between fatty liver and so-called coronary risk factors has rarely been investigated from the viewpoint of prevention of coronary heart disease. The purpose of the present study was to elucidate such a relationship by comparing the coronary risk factors with and without fatty liver by using data from health check-ups for the mid-management and management staff of a manufacturing company. The majority (77.1%) of those with fatty liver in the present study were categorized as "normal" or "marginally obese" and only a small portion (22.9%) were categorized as "obese" according to the classification of the body mass index. The group of subjects with fatty liver had significantly lower mean HDL-cholesterol and higher levels of fasting blood sugar, HDL/total cholesterol ratio, triglyceride, uric acid and transaminases, than those parameters in subjects without fatty liver, even after adjustment for age and body-mass index. The blood pressure (both systolic and diastolic) and total cholesterol level did not show any significant difference after controlling the covariates. Our results indicated that fatty liver has a close correlation with the majority of coronary risk factors causing atheroscleotic diseases, and most of these relationships are independent of total body mass. Our results regarding fatty liver are a help to occupational health personnel when advising workers to reduce their own risk of atherogeic diseases.
Takeda
T
T
Occupational Health Service, Lion Corporation, Tokyo, Japan.
Fujino
A
A
Mizoue
T
T
Kaji
H
H
D000328:Adult; D000367:Age Factors; D001161:Arteriosclerosis / Q000209:etiology; D015992:Body Mass Index; D003327:Coronary Disease / Q000209:etiology* / Q000517:prevention & control; D005234:Fatty Liver / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D016272:Occupational Health; D012307:Risk Factors; D014463:Ultrasonography