Regulation of the ketogenic enzyme mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in astrocytes and meningeal fibroblasts. Implications in normal brain development and seizure neuropathologies.
Cullingford
T E
TE
Department of Neurochemistry, Institute of Neurology, London, U.K.
Bhakoo
K K
KK
Peuchen
S
S
Dolphin
C T
CT
Clark
J B
JB
D000818:Animals; D001253:Astrocytes / Q000201:enzymology*; D001921:Brain / Q000201:enzymology* / Q000254:growth & development; D004268:DNA-Binding Proteins / Q000378:metabolism; D005347:Fibroblasts / Q000201:enzymology; D015971:Gene Expression Regulation, Enzymologic; D006801:Humans; D006904:Hydroxymethylglutaryl-CoA Synthase / Q000235:genetics* / Q000378:metabolism*; D008578:Meninges / Q000201:enzymology*; D008928:Mitochondria / Q000201:enzymology*; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism; D012640:Seizures / Q000201:enzymology* / Q000503:physiopathology; D014157:Transcription Factors / Q000378:metabolism
D004268:DNA-Binding Proteins; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors; D006904:Hydroxymethylglutaryl-CoA Synthase