title: Gas chromatographic method for the determination of toluidines in spiked urine samples.
abstract: A capillary gas-chromatographic method was developed for the analysis of a mixture of toluidines in urine. The method is based on the extraction of toluidines with toluene and derivatisation with heptafluorobutyric anhydride to form a product for electron capture detection. The procedure gave a linear response at concentrations of 0.02-0.20 microg/ml with sufficient reproducibility. The method is simple, requires little sample pretreatment and is being considered for biomonitoring workers exposed to toluidines.
authors.affiliation: Department of Toxicology, Karol Marcinkowski University of Medical Sciences in Poznañ, Poland. liebert@usoms.poznan.pl
authors.forename: J
authors.initials: J
authors.lastname: Jodynis-Liebert
authors.forename: H A
authors.initials: HA
authors.lastname: Bennasir
mesh_terms: D002849:Chromatography, Gas; D006801:Humans; D016273:Occupational Exposure; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014052:Toluidines / Q000652:urine*
chemical_list: D014052:Toluidines