Stability of aluminium-containing adjuvants during aging at room temperature.
Aluminium phosphate adjuvant and aluminium hydroxide adjuvant became more ordered during aging at room temperature. The increased degree of order was accompanied by a decrease in protein adsorption capacity.
Burrell
L S
LS
Department of Industrial and Physical Pharmacy, Purdue University, West Lafayette, IN 47907, USA.
White
J L
JL
Hem
S L
SL
D000276:Adjuvants, Immunologic / Q000737:chemistry*; D000327:Adsorption; D017607:Aluminum Compounds / Q000737:chemistry*; D000536:Aluminum Hydroxide / Q000737:chemistry*; D004355:Drug Stability; D006863:Hydrogen-Ion Concentration; D010710:Phosphates / Q000737:chemistry*
D000276:Adjuvants, Immunologic; D017607:Aluminum Compounds; D010710:Phosphates; D000536:Aluminum Hydroxide; C012714:aluminum phosphate