Pharmacokinetic/pharmacodynamic modeling of theophylline in patients with different degrees of airway obstruction.
Flores-Murrieta
F J
FJ
Departamento de Farmacología y Toxicología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, México, D.F., Mexico.
Mercado
D E
DE
Rodríguez-Silverio
J
J
Chapela
R
R
D000328:Adult; D000402:Airway Obstruction / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D000465:Algorithms; D001249:Asthma / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D013806:Theophylline / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use*
D001993:Bronchodilator Agents; D013806:Theophylline