title: Pseudomembranous colitis: report of a severe case with unusual clinical signs in a young nurse.
abstract: We describe the case of a young and otherwise healthy nurse who developed pseudomembranous colitis ten days after receiving oral clindamycin for dental infection. Her clinical course was particularly stormy and was characterized by severe diarrhea and vomiting, profuse ascites, pleural effusion, abdominal tenderness, peritoneal irritation, and systemic toxicity. The Clostridium difficile assay was negative on two occasions. Features compatible with pseudomembranous colitis were seen at sigmoidoscopy, and the diagnosis was confirmed by biopsies.
authors.affiliation: Department of Surgery B, Wolfson Medical Center, Holon Sackler School of Medicine, Tel Aviv University, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Boaz
authors.forename: M
authors.initials: M
authors.lastname: Dan
authors.forename: I
authors.initials: I
authors.lastname: Charuzi
authors.forename: O
authors.initials: O
authors.lastname: Landau
authors.forename: Y
authors.initials: Y
authors.lastname: Aloni
authors.forename: S
authors.initials: S
authors.lastname: Kyzer
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D001706:Biopsy; D002981:Clindamycin / Q000009:adverse effects; D016360:Clostridioides difficile / Q000302:isolation & purification; D003428:Cross Infection; D003937:Diagnosis, Differential; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced / Q000175:diagnosis* / Q000382:microbiology; D005260:Female; D006801:Humans; D009726:Nurses; D012812:Sigmoidoscopy
chemical_list: D000900:Anti-Bacterial Agents; D002981:Clindamycin