Caenorhabditis elegans for the study of host-pathogen interactions.
The nematode worm Caenorhabditis elegans, for which the complete genome sequence is available, has several other advantages as an experimental system, and has already been widely used as a model for the study of vertebrate biology. Recent investigations have revealed that C. elegans could also be an extremely useful model system in the study of bacterial pathogenesis and have reinforced the notion that common virulence and host defence mechanisms exist.
Kurz
C L
CL
Centre d'Immunologie de Marseille-Luminy, INSERM/CNRS/Université de la Méditerranée, Case 906, 13288 Marseille Cedex 9, France.
Ewbank
J J
JJ
D000818:Animals; D017173:Caenorhabditis elegans / Q000382:microbiology*; D006801:Humans; D011550:Pseudomonas aeruginosa / Q000472:pathogenicity*; D012706:Serratia marcescens / Q000472:pathogenicity*; D014774:Virulence