title: Structural features for fluorescing present in methoxycoumarin derivatives.
abstract: Structural features of fluorescent methoxycoumarins were examined from the viewpoint of substituent effect and ring structure in connection with intramolecular charge-transfer (ICT). The fluorescence of methoxycoumarins depended primarily upon the ICT from a C6-electron-donating group to the substituents at the C3-position of the coumarin ring. Furthermore, the presence of a lactone ring itself, including a carbonyl group, cyclic ether oxygen and ethylenic bond as partial ring structures, was found to be essential for fluorescing in methoxycoumarins according to the fluorescent behaviors of chemically deformed model compounds.
authors.affiliation: Daiichi College of Pharmaceutical Sciences, Fukuoka, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Takadate
authors.forename: T
authors.initials: T
authors.lastname: Masuda
authors.forename: C
authors.initials: C
authors.lastname: Murata
authors.forename: M
authors.initials: M
authors.lastname: Shibuya
authors.forename: A
authors.initials: A
authors.lastname: Isobe
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003374:Coumarins / Q000138:chemical synthesis / Q000737:chemistry*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008738:Methyl Ethers / Q000138:chemical synthesis / Q000737:chemistry; D013050:Spectrometry, Fluorescence
chemical_list: D003374:Coumarins; D005456:Fluorescent Dyes; D007202:Indicators and Reagents; D008738:Methyl Ethers