Flow-injection spectrophotometric methods for the determination of tenoxicam.
Two sensitive and rapid flow-injection spectrophotometric methods are proposed for the determination of tenoxicam (TX). In the first method, a Fe(III)-tenoxicam complex is formed in a methanolic medium and the absorbance is measured at 540 nm, while the second method involves measurement of the absorbance at 355 nm of a solution containing the drug in hydrochloric acid medium. In both methods, the peak heights were proportional to tenoxicam concentration over the ranges 7.0-320 and 0.5-8.5 mg/l(-1), respectively. The methods have been applied to the routine determination of the drug in dosage forms.
García
M S
MS
Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Spain.
Sánchez-Pedreño
C
C
Albero
M I
MI
Gimenez
M J
MJ
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000032:analysis*; D017022:Flow Injection Analysis; D004364:Pharmaceutical Preparations / Q000032:analysis; D010894:Piroxicam / Q000031:analogs & derivatives* / Q000032:analysis; D013053:Spectrophotometry / Q000379:methods
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004364:Pharmaceutical Preparations; D010894:Piroxicam; C032801:tenoxicam