title: The urological complications of renal transplantation: an 11-year-experience at Ramathibodi Hospital.
abstract: From February 1986 to December 1996, renal transplantation was performed on 344 patients at Ramathibodi Hospital. The urological complications were retrospectively analyzed in 335 patients (338 renal transplants), 9 patients were lost to follow-up. There were 227 males and 108 females with age ranging from 15 to 62 years (mean age 40.28 years). There were 207 cadaveric and 131 living-related graft donors. The ureteroneocystostomy was performed either by modified Politano-Leadbetter (93 cases) or extravesical technique (245 cases). There were 23 cases of urological complications: ureterovesical anastomotic leakage 6, ureteric obstruction 6, vesicoureteric reflux 4, significant bleeding from ureterovesical anastomosis 3, renal infarction with fistulas 2, hydronephrosis due to blood clot retention and swelling of the anastomosis, requiring temporary double J stenting 2. The analysis was done by dividing the patients into 3 groups, the first and second groups consisted of 100 cases each and the third group consisted of 138 cases. The urological complications in the groups were 10 per cent, 9 per cent and 2.89 per cent respectively. There was a statistically significant difference between the first two groups combined and the third group in terms of complications (p < 0.025). The urological complications of living-related cases were 9 (6.87%), and of cadaveric cases were 14 (6.76%). There was no significant difference of the complications between living-related and cadaveric transplants (p < 0.05). The comparative results of the ureteric complications of the extravesical technique were significantly less than the modified Politano-Leadbetter technique (4.49% vs 10.75%), (p < 0.05). In conclusion, the extravesical technique of ureterovesical anastomosis was superior than the modified Leadbetter-Politano technique in terms of post-operative ureteral complications.
authors.affiliation: Division of Urology, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Leungwattanakij
authors.forename: P
authors.initials: P
authors.lastname: Eamtanaporn
authors.forename: W
authors.initials: W
authors.lastname: Kochakarn
authors.forename: P
authors.initials: P
authors.lastname: Gojaseni
authors.forename: S
authors.initials: S
authors.lastname: Chaimuangrat
authors.forename: C
authors.initials: C
authors.lastname: Leenanupunth
authors.forename: S
authors.initials: S
authors.lastname: Jirasiritham
authors.forename: V
authors.initials: V
authors.lastname: Muangman
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection; D006085:Graft Survival; D006786:Hospitals, Urban; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000379:methods; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate; D013785:Thailand / Q000453:epidemiology; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D014570:Urologic Diseases / Q000209:etiology* / Q000401:mortality / Q000628:therapy