Bilateral juxtafoveolar telangiectasis in monozygotic twins.
OBJECTIVE
To report the clinical and angiographic features of two monozygotic twins affected by bilateral group 2 idiopathic juxtafoveolar telangiectasis.


METHODS
Case reports.


RESULTS
Two 64-year-old women, who were identical twins, were suffering from visual loss. One twin had suffered from visual loss for 1 year and had a visual acuity of 20/25 in both eyes, and the other twin had suffered for 2 years and had a visual acuity of 20/30 in both eyes. Fluorescein angiography disclosed similar fundus features. An analogous area of capillary telangiectasis and leakage was observed in the right macula, where no intraretinal pigment was seen; the left macula showed a similar amount of intraretinal pigment associated with tiny right-angle venules and minimal leakage.


CONCLUSIONS
This observation raises the issue of genetic influences in the pathogenesis of this disease.
Menchini
U
U
Department of Ophthalmology, University of Udine, Italy. Ugo.Menchini@dsc.uniud.it
Virgili
G
G
Bandello
F
F
Malara
C
C
Rapizzi
E
E
Lanzetta
P
P
D004200:Diseases in Twins / Q000235:genetics*; D005260:Female; D005451:Fluorescein Angiography; D005584:Fovea Centralis / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D009898:Optic Disk / Q000098:blood supply* / Q000473:pathology; D012164:Retinal Diseases / Q000235:genetics* / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology*; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000235:genetics* / Q000473:pathology; D014430:Twins, Monozygotic; D014792:Visual Acuity