title: Cognitive-behavioral stress management increases free testosterone and decreases psychological distress in HIV-seropositive men.
abstract: The effects of a 10-week group-based cognitive-behavioral stress management (CBSM) intervention on psychological distress and plasma free testosterone in symptomatic, HIV-seropositive men were examined. Participants were randomized to either CBSM (n = 42) or a wait-list control group (n = 23). Men in the CBSM intervention showed significant increases in testosterone, whereas control participants showed significant decreases. Those participating in CBSM had significant distress reductions, whereas controls showed no such change. Alterations in free testosterone were inversely related to changes in distress states over time, independent of any changes in cortisol. These findings demonstrate that a short-term CBSM intervention increases free testosterone levels among symptomatic, HIV-seropositive men, and alterations in free testosterone are associated with changes in psychological distress observed during CBSM.
authors.affiliation: Department of Psychology, University of Miami, Coral Gables, Florida 33124-2070, USA.
authors.forename: D G
authors.initials: DG
authors.lastname: Cruess
authors.forename: M H
authors.initials: MH
authors.lastname: Antoni
authors.forename: N
authors.initials: N
authors.lastname: Schneiderman
authors.forename: G
authors.initials: G
authors.lastname: Ironson
authors.forename: P
authors.initials: P
authors.lastname: McCabe
authors.forename: J B
authors.initials: JB
authors.lastname: Fernandez
authors.forename: S E
authors.initials: SE
authors.lastname: Cruess
authors.forename: N
authors.initials: N
authors.lastname: Klimas
authors.forename: M
authors.initials: M
authors.lastname: Kumar
mesh_terms: D000328:Adult; D001521:Behavior Therapy; D015928:Cognitive Behavioral Therapy; D015658:HIV Infections / Q000523:psychology*; D006801:Humans; D008297:Male; D011788:Quality of Life; D013315:Stress, Psychological / Q000517:prevention & control / Q000628:therapy*; D013739:Testosterone / Q000097:blood*; D016896:Treatment Outcome
chemical_list: D013739:Testosterone