[Disorders of bone metabolism in gastrointestinal and hepatic diseases].
Gastrointestinal and hepatic diseases are frequently associated with metabolic bone disorders, especially osteoporosis and osteomalacia. Malabsorption of vitamin D and calcium are important aetiological factors, although other factors may contribute, like the use of glucocorticosteroids in the treatment of inflammatory bowel disease. Treatment is first of all focused on correction of calcium and vitamin D deficiency. In severe osteoporosis additional treatment with bisfosfonates needs serious consideration.
van Daele
P L
PL
Afd. Inwendige Geneeskunde, Academisch Ziekenhuis Rotterdam-Dijkzigt. vandaele@inw3.azr.nl
Pols
H A
HA
D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D001851:Bone Diseases, Metabolic / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism* / Q000493:pharmacokinetics / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005743:Gastrectomy / Q000009:adverse effects; D005767:Gastrointestinal Diseases / Q000150:complications*; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications; D008107:Liver Diseases / Q000150:complications*; D008286:Malabsorption Syndromes / Q000150:complications* / Q000378:metabolism; D009748:Nutrition Disorders; D015995:Prevalence; D014807:Vitamin D / Q000031:analogs & derivatives / Q000378:metabolism* / Q000493:pharmacokinetics / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D014807:Vitamin D; D002118:Calcium