[The toxicity and interferon-inducing activity of the lipopolysaccharides of Cytophaga sp. (strains 81 and 92)].
The experiments on mice and cell culture of a kidney of green monkey Vero have shown that lipopolysaccharides (LPS) of the studied strains 81 and 92 of Cytophaga sp. were nontoxic. They were less active as compared to LPS of other Gram-negative bacteria as to interferon-inducing activity. A comparative study of initial and dephosphorylated LPS has shown that phosphate groups were not responsible for the interferon-inducing activity of LPS of Cytophaga genus representatives.
Varbanets
L D
LD
Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Kyiv.
Ivanitsa
V A
VA
Brovarskaia
O S
OS
Zimakovskaia
L A
LA
Rybalko
S L
SL
Diadiun
S T
ST
Seĭfullina
I I
II
D000818:Animals; D002478:Cells, Cultured; D002522:Chlorocebus aethiops; D003589:Cytophaga / Q000472:pathogenicity*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007369:Interferon Inducers / Q000494:pharmacology*; D007962:Leukocytes / Q000187:drug effects; D008070:Lipopolysaccharides / Q000494:pharmacology / Q000633:toxicity*; D051379:Mice; D008938:Mitosis / Q000187:drug effects; D012623:Seawater / Q000382:microbiology; D013997:Time Factors; D014709:Vero Cells
D007369:Interferon Inducers; D008070:Lipopolysaccharides