Malignant evolution of choroid plexus papilloma.
Choroid plexus tumors are rare CNS neoplasms. The distinction between choroid plexus papilloma (CPP) and choroid plexus carcinoma (CPC) is made on the basis of clinical and histological criteria. Malignant evolution of CPP may occur, and the presence of mitotic figures in CPP may predict the likelihood of recurrence or malignant evolution. Close surveillance is mandated for these patients. We report on two such cases of CPP that transformed to CPC at the time of recurrence.
Chow
E
E
Department of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tenn 38105, USA.
Jenkins
J J
JJ
Burger
P C
PC
Reardon
D A
DA
Langston
J W
JW
Sanford
R A
RA
Heideman
R L
RL
Kun
L E
LE
Merchant
T E
TE
D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D002675:Child, Preschool; D002831:Choroid Plexus / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D020288:Papilloma, Choroid Plexus / Q000473:pathology* / Q000601:surgery; D012086:Reoperation