Continuous production of N-(benzyloxycarbonyl)-L-glycyl-L-phenylalanine methyl ester utilizing extractive reaction in aqueous/organic biphasic medium.
N-(Benzyloxycarbonyl)-L-glycyl-L-phenylalanine methyl ester was continuously synthesized, enzymatically, utilizing an extractive reaction in an aqueous/organic biphasic system. The extremely high yield, ca. 100%, was obtained continuously in a water/butyl acetate biphasic medium.
Murakami
Y
Y
Department of Chemical Engineering, Waseda University, Tokyo, Japan.
Oda
T
T
Chiba
K
K
Hirata
A
A
D004151:Dipeptides / Q000138:chemical synthesis* / Q000737:chemistry; D010452:Peptide Biosynthesis
D004151:Dipeptides; C405945:N-benzyloxycarbonyl-glycyl-phenylalanine methyl ester