title: Flow-injection extraction-spectrophotometric method for the determination of chlorhexidine in pharmaceutical preparations.
abstract: The spectrophotometric determination of trace amounts of chlorhexidine was carried out by liquid-liquid extraction using bromophenol blue with a flow system. The determination of chlorhexidine in the range of 1 x 10(-4) to 1 x 10(-5) M was possible with a sampling frequency of 40 samples per hour. The method was satisfactorily applied to the determination of chlorhexidine in pharmaceutical preparations.
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Spain. tpr@fcu.um.es
authors.forename: T
authors.initials: T
authors.lastname: Pérez-Ruiz
authors.forename: C
authors.initials: C
authors.lastname: Martínez-Lozano
authors.forename: A
authors.initials: A
authors.lastname: Sanz
authors.forename: A
authors.initials: A
authors.lastname: Sánchez
mesh_terms: D000891:Anti-Infective Agents, Local / Q000032:analysis*; D001978:Bromphenol Blue; D002710:Chlorhexidine / Q000032:analysis*; D017022:Flow Injection Analysis; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D015203:Reproducibility of Results; D012997:Solvents; D013053:Spectrophotometry / Q000379:methods
chemical_list: D000891:Anti-Infective Agents, Local; D004364:Pharmaceutical Preparations; D012997:Solvents; D001978:Bromphenol Blue; D002710:Chlorhexidine