Furoquinolines with antiplatelet aggregation activity from leaves of Melicope confusa.
Using antiplatelet aggregation as a guide for fractionation, four furoquinoline-type alkaloids, confusameline (1), skimmianine (2), kokusaginine (3), and O-methylconfusameline (4), were isolated from the leaves of Melicope confusa. All compounds showed significant antiplatelet aggregation activity.
Chen
K S
KS
Chang
Y L
YL
Teng
C M
CM
Chen
C F
CF
Wu
Y C
YC
D000818:Animals; D066298:In Vitro Techniques; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D011804:Quinolines / Q000494:pharmacology*; D011817:Rabbits; D014197:Trees / Q000737:chemistry
D010975:Platelet Aggregation Inhibitors; D011804:Quinolines