Corticosteroid cross-reactions: an alternative view.
An alternative view of corticosteroid cross-reactivity is proposed, based on 2 immune recognition sites on the corticosteroid molecule, 1 influenced by C 6/9 substitution and 1 by C 16/17 substitution. A case report is adduced in support of such a hypothesis.
Wilkinson
S M
SM
Department of Dermatology, The General Infirmary, Leeds, UK.
D000287:Administration, Topical; D000328:Adult; D000485:Allergens / Q000276:immunology*; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000276:immunology* / Q000378:metabolism; D019819:Budesonide / Q000009:adverse effects; D003429:Cross Reactions; D017449:Dermatitis, Allergic Contact / Q000209:etiology; D003879:Dermatologic Agents / Q000737:chemistry / Q000276:immunology* / Q000378:metabolism; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000009:adverse effects / Q000031:analogs & derivatives; D015394:Molecular Structure
D000485:Allergens; D000893:Anti-Inflammatory Agents; D003879:Dermatologic Agents; D019819:Budesonide; C019112:tixocortol pivalate; D006854:Hydrocortisone