title: Primary epitheliotropic T-cell lymphoma of the urinary bladder in a dog.
abstract: A 7-year-old, intact female mixed-breed dog was presented for evaluation of hematuria. Physical examination revealed a suprapubic mass. Ultrasonographic examination showed a large lobular mass occupying the urinary bladder. At the owners' request, the dog was euthanatized and a postmortem examination was performed. Necropsy confirmed the presence of a lobular mass of about 5- to 6-cm diameter protruding into the lumen of the bladder. Histologically, the mass was composed of a large number of atypical lymphoid cells in the lamina propria and mucosal epithelium. Immunohistochemically, the neoplastic cells expressed CD3 but not CD79alpha or keratin and vimentin, supporting a diagnosis of T-cell lymphoma.
authors.affiliation: Dipartimento di Patologia e Sanità Animale, Settore Anatomia Patologica, Facoltà di Medicina Veterinaria, Università degli Studi di Napoli Federico II, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Maiolino
authors.forename: G
authors.initials: G
authors.lastname: DeVico
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D000818:Animals; D017252:CD3 Complex / Q000276:immunology; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D004848:Epithelium / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006417:Hematuria / Q000662:veterinary; D007150:Immunohistochemistry; D016399:Lymphoma, T-Cell / Q000473:pathology / Q000662:veterinary*; D011860:Radiography, Abdominal / Q000662:veterinary; D014463:Ultrasonography; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000662:veterinary*
chemical_list: D017252:CD3 Complex