title: SPAC: identification of polypeptides using their amino-acid composition.
abstract: We describe here new software able to retrieve from protein or nucleic acid databases, the sequence corresponding to a protein or peptide whose only amino acid composition and molecular weight are known. This algorithm is particularly devoted to the retrieval of partial sequences, a task that other available software performs poorly. Its accuracy for the attribution of a protein fragment to a sequence could represent an easy and economical first tool upstream the use of more sophisticated and expensive methods in proteomic research. SPAC (Sequence Protein Alignment with Composition) is a shareware available software on web site http://www.univ-tln.fr/ approximately grillas/SPAC/. This web site also presents help and a detailed description of the algorithm and interface.
authors.affiliation: Département de Génie Biologique, Université de Toulon et du Var, La Garde, France. grillasca@univ-tln.fr
authors.forename: J P
authors.initials: JP
authors.lastname: Grillasca
authors.forename: R
authors.initials: R
authors.lastname: Planells
authors.forename: D
authors.initials: D
authors.lastname: Aubert
authors.forename: F
authors.initials: F
authors.lastname: Antonini
mesh_terms: D000465:Algorithms; D000596:Amino Acids / Q000032:analysis*; D000818:Animals; D016208:Databases, Factual; D006801:Humans; D008970:Molecular Weight; D010446:Peptide Fragments / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry; D015203:Reproducibility of Results; D016415:Sequence Alignment / Q000379:methods / Q000706:statistics & numerical data; D012984:Software
chemical_list: D000596:Amino Acids; D010446:Peptide Fragments; D010455:Peptides; D011506:Proteins