Effect of adrenalin and propranolol on progesterone and oxytocin secretion in vivo during the caprine estrous cycle.
The effects of jugular infusions of adrenalin and the beta-adrenergic receptor antagonist propranolol on plasma concentrations of progesterone and oxytocin were examined at 2 different stages of the caprine estrous cycle. Adrenalin (25 micrograms.kg-1h-1) significantly (P < 0.05) increased oxytocin secretion on Day 3 and Day 10 of the cycle (estrus = Day 0); progesterone concentrations were significantly (P < 0.05) elevated on Day 10 alone. Propranolol had no effect on progesterone secretion yet significantly (P < 0.05) reduced oxytocin concentrations on Day 3. These results suggest that there may be neuroendocrine involvement in the regulation of luteal oxytocin secretion in the goat.
Payne
J H
JH
Department of Veterinary Preclinical Sciences, University of Liverpool, United Kingdom.
Cooke
R G
RG
D000818:Animals; D004837:Epinephrine / Q000008:administration & dosage / Q000494:pharmacology*; D004971:Estrus / Q000187:drug effects* / Q000502:physiology; D005260:Female; D006041:Goats / Q000502:physiology*; D007262:Infusions, Intravenous; D010121:Oxytocin / Q000097:blood* / Q000378:metabolism; D011374:Progesterone / Q000097:blood* / Q000378:metabolism; D011433:Propranolol / Q000008:administration & dosage / Q000494:pharmacology*
D011374:Progesterone; D010121:Oxytocin; D011433:Propranolol; D004837:Epinephrine