Developments and improvements in the manufacturing of human therapeutics with mammalian cell cultures.
During recent years, biopharmaceutical products manufactured by processes that use mammalian cell cultures have gained increasing importance. At the same time, a strong awareness of the importance of the safety and quality of such products has also emerged. This has led to improvements in cultivation and production technology, validation procedures and process organization.
Hesse
F
F
Cell Culture Technology Department, Gesellschaft für Biotechnologische Forschung mbH, 38124 Braunschweig, Germany.
Wagner
R
R
D000818:Animals; D018070:Biological Specimen Banks; D001709:Biotechnology / Q000379:methods / Q000639:trends; D018929:Cell Culture Techniques / Q000379:methods*; D003470:Culture Media / Q000737:chemistry; D004345:Drug Industry / Q000379:methods* / Q000639:trends*; D017408:Guidelines as Topic; D006801:Humans; D008322:Mammals; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism; D018570:Risk Assessment
D003470:Culture Media; D011994:Recombinant Proteins