Lichen amyloidosus: a bullous variant.
BACKGROUND
Lichen amyloidosus is a common skin disease seen among Asian patients.


METHODS
Typical features range from macular hyperpigmentation to pruritic, lichenified, hyperpigmented papules. However, in this rare bullous variant of lichen amyloidosus, bullae and vesicles are present. Histopathologically, deposits of amyloid were seen in the papillary dermis, associated with an intraepidermal or subepidermal blister.


RESULTS
No good treatment so far, but pruritus can be relieved by topical steroid.


CONCLUSIONS
It is important to screen for systemic amyloidosis with the relevant investigations as it can present similarly with blistering eruptions, in which the prognosis would be grave.
Khoo
B P
BP
National Skin Centre, Singapore.
Tay
Y K
YK
D000328:Adult; D000686:Amyloidosis / Q000473:pathology*; D006801:Humans; D017512:Lichenoid Eruptions / Q000473:pathology*; D008297:Male