Gel electrophoretic distinction between Congo Red nonreactive beta-amyloid (1-42) and beta-amyloid (1-40).
Congo-Red nonreactive beta-amyloid (1-42) exhibits in gel electrophoresis (pH 8.82, 0.01 M ionic strength, 2 degree C) a surface charge density larger than that of the corresponding peptide of length (1-40), and a size indistinguishable from that of (1-40).
Chrambach
A
A
Laboratory of Cellular and Molecular Biophysics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1580, USA. acc@cu.nih.gov
Chrambach
A
A
Brining
S K
SK
D016229:Amyloid beta-Peptides / Q000302:isolation & purification*; D003224:Congo Red; D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods; D006801:Humans; D010446:Peptide Fragments / Q000302:isolation & purification*; D011485:Protein Binding
D016229:Amyloid beta-Peptides; D010446:Peptide Fragments; C078592:amyloid beta-protein (1-40); C075222:amyloid beta-protein (1-42); D003224:Congo Red