title: Idiopathic prolonged QT interval and QT dispersion: the effects of propofol during implantation of cardioverter-defibrillator.
abstract: Local anaesthesia combined with conscious sedation is becoming a popular technique for implantation of cardioverter-defibrillator devices. Propofol was given to provide loss of consciousness during defibrillation shock administration, for induced ventricular fibrillation testing. Propofol was found to decrease QT interval and QT dispersion in two patients with idiopathic prolonged QT interval and QT dispersion. The findings of the procedure are reported.
authors.affiliation: Department of Anaesthesiology, University Hospital, Iraklion 71110, Crete, Greece.
authors.forename: D
authors.initials: D
authors.lastname: Michaloudis
authors.forename: O
authors.initials: O
authors.lastname: Fraidakis
authors.forename: E
authors.initials: E
authors.lastname: Kanoupakis
authors.forename: A
authors.initials: A
authors.lastname: Flossos
authors.forename: E
authors.initials: E
authors.lastname: Manios
mesh_terms: D000328:Adult; D000772:Anesthesia, Local; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D001794:Blood Pressure / Q000187:drug effects; D002304:Cardiac Pacing, Artificial / Q000379:methods; D016292:Procedural Sedation; D003243:Consciousness / Q000187:drug effects; D017147:Defibrillators, Implantable; D004562:Electrocardiography / Q000187:drug effects*; D015716:Electrocardiography, Ambulatory / Q000187:drug effects; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008133:Long QT Syndrome / Q000503:physiopathology / Q000628:therapy*; D008875:Middle Aged; D015742:Propofol / Q000008:administration & dosage*; D014693:Ventricular Fibrillation / Q000503:physiopathology
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol