[The factors influencing the effectiveness of treatment for brain tumors in children].
In this paper we analysed the group of 110 children (60 boys and 50 girls) that between 1982-1992 has been operated and some of them treated multidisciplinary because of a brain tumor. The disease was mainly recognised in 3-7 year old children (49). The tumor was situated in the vermis cerebelli and in the IV ventricle (31), in the hemispherium cerebelli (20), in the region of the III ventrical (18), in the hemispherium cerebri (16), in the pons and medulla oblongata (11), and in the sellar region (11). In the histopathological report in most cases we recognised astrocytoma (32), medulloblastma (18), ependymoma (12) and craniopharyngiona (6). The tumor tissue was not taken for the histopathological examination because of a very dangerous approach in 34 patients. The malignancy state was low in 51 and high in 25 cases. The implantation of the shunt was carried on in 86 children. In 77 cases the resection of the tumor was done: total (9), subtotal (39), partial (24) and biopsy (5). The post operative radiotherapy was used in 71 and chemotherapy (Bloom's scheme) in 43 patients. According to treatment results (Karnofsky's scale) and analysis of survival curves (Log-Rank test) the most important influence in the final outcome have: malignancy, histological structure and localisation of a tumor, extent of resection and radiotherapy.
Jarmusz
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Oddziału Neurochirurgii Katedry i Kliniki Chirurgii Dzieciecej Akademii Medycznej w Poznaniu.
D001932:Brain Neoplasms / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D010348:Patient Care Team; D012189:Retrospective Studies; D016896:Treatment Outcome