Congenital misalignment of pulmonary veins with alveolar capillary dysplasia causing persistent neonatal pulmonary hypertension: report of two affected siblings.
Misalignment of pulmonary vessels with alveolar capillary dysplasia is a rare cause of persistent pulmonary hypertension of the newborn. Most of the reported cases have been sporadic. We present two consecutive affected siblings with this disorder. This is the fifth reported family occurrence of this condition. In addition to the pulmonary abnormality, one of our cases had duodenal atresia.
Gutierrez
C
C
Pediatric Pathology Laboratory, Hospital Pereira Rossell, Boulevard Artigas 1550, Casilla de Correo 16059, Montevideo, Uruguay,
Rodriguez
A
A
Palenzuela
S
S
Forteza
C
C
Rossello
J L
JL
D001165:Arteriovenous Malformations / Q000473:pathology*; D001980:Bronchi / Q000098:blood supply; D002196:Capillaries / Q000002:abnormalities; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000098:blood supply* / Q000473:pathology; D009679:Nuclear Family; D010547:Persistent Fetal Circulation Syndrome / Q000209:etiology / Q000473:pathology*; D011650:Pulmonary Alveoli / Q000098:blood supply; D011651:Pulmonary Artery / Q000002:abnormalities*; D011667:Pulmonary Veins / Q000002:abnormalities*