title: Prefabricated (expander) capsule-lined transposition and advancement flaps in reconstruction of lower eyelid and oral defects: an experimental study.
abstract: In six pigs with prefabricated transposition flaps and six pigs with prefabricated advancement flaps, both flap types (lined with an expander capsule) were used to reconstruct wedge excisions of the lower eyelid or defects in the cheek/oral mucosa. The capsules replaced the conjunctiva in eyelid defects and the oral mucosa in cheek defects. Histopathologic studies were performed at 5 to 7 days, 9 to 10 days, 2 weeks, 3 to 4 weeks, and 2 and 3 months after flap reconstructions. Healing was rapid and uneventful, leading to restoration of the conjunctiva/eyelid and oral mucosa between 9 days and 2 weeks. The healing of the eyelid conjunctiva was somewhat faster than of the oral mucosa. The expander capsule acted as a conjunctival/ mucosal substitute, providing a temporary physical shield, an infectious barrier, and a matrix for epithelial regeneration. All reconstructions were successful except one oral reconstruction with early flap necrosis. Flaps lined with an expander capsule could improve and facilitate clinical reconstructions in the eyelid and oral cavity.
authors.affiliation: Institute of Plastic Surgery, Malmö, Sweden. plasticsurgery@plasticsurgery.nu
authors.forename: J B
authors.initials: JB
authors.lastname: Wieslander
authors.forename: M
authors.initials: M
authors.lastname: Wieslander
mesh_terms: D000818:Animals; D003228:Conjunctiva / Q000473:pathology; D005143:Eyelids / Q000473:pathology / Q000601:surgery*; D009061:Mouth Mucosa / Q000473:pathology / Q000601:surgery*; D013524:Surgical Flaps / Q000473:pathology*; D013552:Swine; D015625:Tissue Expansion Devices; D014945:Wound Healing / Q000502:physiology