Influence of electric field strength and capillary dimensions on the separation of DNA.
This work is a continuation of earlier studies on the influence of polymer concentration and polymer composition on the capillary electrophoretic separation of DNA. The focus is on the capillary dimensions and the electric field strength as factors influencing the resolution. The aim was to establish optimum conditions for the separation of single-stranded DNA in capillaries and derive strategies for the construction of micromachined separation devices.
Heller
C
C
Abt. Lehrach, Max-Planck-Institut für molekulare Genetik, Berlin-Dahlem, Germany. cheller@analyticon-ag.com
D004247:DNA / Q000302:isolation & purification*; D004560:Electricity; D019075:Electrophoresis, Capillary / Q000379:methods*
D004247:DNA