Unveiling ribosomal structures: the final phases.
Unprecedented insights into the structure of the ribosome have been gained recently: X-ray crystallographic studies have yielded 5-9 A resolution structures and cryo-electron microscopy has elucidated the structure of the Escherichia coli ribosome in different functional states. A 7.5 A cryo-electron microscopy structure of the large subunit indicates that this technique is still in the race to determine the ribosome structure.
van Heel
M
M
Department of Biochemistry, Imperial College of Science, Technology and Medicine, London, SW7 2AY, UK. m.vanheel@ic.ac.uk
D020285:Cryoelectron Microscopy; D018360:Crystallography, X-Ray; D003626:Data Display; D004926:Escherichia coli / Q000648:ultrastructure; D008958:Models, Molecular; D012270:Ribosomes / Q000648:ultrastructure*; D016963:Thermus thermophilus / Q000648:ultrastructure