title: Biosynthesis of depudecin, a metabolite of Nimbya scirpicola.
abstract: Feeding experiments of labeled acetates to Nimbya scirpicola proved the carbon origin of the straight-chain polyketide, depudecin. Differential hydrogen exchange of the 2H label originating from 2H labeled acetate along the polyketide chain occurred. In particular, the deuterium of an epoxide methine at C-3 was lost to a substantial extent in the formation of depudecin.
authors.affiliation: Plant Protection Research Laboratory, Japan Tobacco Inc., Yokohama, Kanagawa. masayasu.tanaka@ims.jti.co.jp
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: T
authors.initials: T
authors.lastname: Fujimori
authors.forename: K
authors.initials: K
authors.lastname: Nabeta
mesh_terms: D000466:Alkadienes / Q000737:chemistry / Q000378:metabolism*; D004852:Epoxy Compounds / Q000737:chemistry / Q000378:metabolism*; D005233:Fatty Alcohols / Q000737:chemistry / Q000378:metabolism*; D005285:Fermentation; D005658:Fungi / Q000254:growth & development / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy
chemical_list: D000466:Alkadienes; D004852:Epoxy Compounds; D005233:Fatty Alcohols; C072251:depudecin