Methadone as a rescue for failed high-dose opiate therapy for catastrophic pain.
Methadone is a unique opioid with several special properties besides being a mu agonist, which makes for difficulty in the calculation of equianalgesic doses. A series of three cases is presented to illustrate this point.
Davis
M P
MP
Columbus Oncology Associates, Ohio, USA.
D000284:Administration, Oral; D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D001943:Breast Neoplasms; D002294:Carcinoma, Squamous Cell; D005260:Female; D006258:Head and Neck Neoplasms; D006801:Humans; D008297:Male; D008691:Methadone / Q000008:administration & dosage*; D008875:Middle Aged; D010148:Intractable Pain / Q000188:drug therapy*; D010166:Palliative Care; D011471:Prostatic Neoplasms
D000701:Analgesics, Opioid; D008691:Methadone