title: Racial differences in acute and cumulative skin irritation responses between Caucasian and Asian populations.
abstract: Japanese, and Chinese subjects. In this 2nd study, no differences were seen in the acute or cumulative irritation responses between the Japanese and Caucasian subjects. The Chinese subjects showed a heightened response to 10% acetic acid (after 4 h of exposure), but otherwise displayed a similar response profile in the acute irritation test. They showed a slower and less severe response in the cumulative irritation test compared to the Caucasian or Japanese subjects. These divergent results underscore the difficulty in ascribing true population-based differences in skin reactivity based upon studies in limited subject populations. It may be possible to detect differences in individual studies, but repeat testing may fail to confirm a consistent trend. These findings may be indicative of the wide variation in skin responsiveness across human subjects in general.
authors.affiliation: The Procter & Gamble Company, Miami Valley Laboratories, Cincinnati, Ohio 45253-8707, USA.
authors.forename: M K
authors.initials: MK
authors.lastname: Robinson
mesh_terms: D044466:Asian People; D003877:Dermatitis, Contact / Q000453:epidemiology* / Q000276:immunology*; D006801:Humans; D044465:White People