Clear cell carcinoma of the fimbria of the fallopian tube in a BRCA1 carrier undergoing prophylactic surgery.
We report the case history of a patient with a family history of breast and ovarian cancer who was subsequently found to be a carrier of the BRCA1 gene, in whom a tiny focus of clear cell carcinoma was found at the fimbrial end of one fallopian tube when she underwent prophylactic hysterectomy and bilateral salpingoophorectomy. The implications of this finding are discussed.
Hartley
A
A
Queen Elizabeth Centre for the Treatment of Cancer, University Hospitals Birmingham, UK.
Rollason
T
T
Spooner
D
D
D018262:Adenocarcinoma, Clear Cell / Q000235:genetics*; D001943:Breast Neoplasms / Q000235:genetics / Q000517:prevention & control / Q000601:surgery; D005185:Fallopian Tube Neoplasms / Q000235:genetics*; D005260:Female; D019398:Genes, BRCA1 / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000235:genetics / Q000517:prevention & control / Q000601:surgery; D010052:Ovariectomy