[Immunologic risk analysis of blood transfusion: 1991-1998].
The immunologic risk associated to erythrocyte transfusions is bound to the polymorphism of blood group systems and to the respect of blood transfusion regulations. The results of three studies are presented, which were carried out respectively by the French Society of Blood Transfusion, the National Institute of Blood Transfusion and the National Haemovigilance Network. Two hundred and twenty-seven cases of immunologic accidents are analysed using the Kaplan's interpretation model and the traditional method of process analysis. The results show three critical factors in the occurrence of this type of incident: the relevance of the clinical examinations prescribed, the way in which the biological results are taken into account, and the relationship/exchange of information between private and public hospitals, and blood transfusion centers.
Rouger
P
P
Institut national de la transfusion sanguine (INTS), centre national de référence pour les groupes sanguins (CNRGS), université Pierre-et-Marie-Curie, Inserm U76, Paris, France.
Le Pennec
P Y
PY
Noizat-Pirenne
F
F
D000017:ABO Blood-Group System / Q000032:analysis / Q000276:immunology; D000059:Accidents; D001787:Blood Group Incompatibility / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D001788:Blood Grouping and Crossmatching; D001803:Blood Transfusion / Q000706:statistics & numerical data*; D017707:Erythrocyte Transfusion / Q000009:adverse effects / Q000706:statistics & numerical data; D005568:Forms and Records Control; D005602:France; D006801:Humans; D007518:Isoantibodies / Q000276:immunology; D019300:Medical Errors; D008499:Medical Records; D011110:Polymorphism, Genetic; D012189:Retrospective Studies; D018570:Risk Assessment; D012308:Risk Management; D065227:Transfusion Reaction
D000017:ABO Blood-Group System; D007518:Isoantibodies