[Specific features of immunity in patients with different forms of pulmonary tuberculosis].
The cellular immunity was studied in 59 patients with pulmonary tuberculosis. The development of tuberculous infection was ascertained to be accompanied by decreases in the relative counts of CD9, CD8, and CD72 lymphocytes, as well as monocytes, expressing class II histocompatibility antigens (DR). The patients with tuberculosis were found to have suppressed proliferative T-cell activity and IL-2 production, moderately decreased IL-1 production and increased TNF alpha secretion.
Khonina
N A
NA
Nikonov
S D
SD
Shpilevskiĭ
S V
SV
Leplina
O Iu
OIu
Shevela
E Ia
EIa
Sakhno
L V
LV
Ostanin
A A
AA
Chernykh
E R
ER
D000328:Adult; D015703:Antigens, CD / Q000276:immunology; D000944:Antigens, Differentiation, B-Lymphocyte / Q000276:immunology; D015415:Biomarkers; D016827:CD8 Antigens / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D007375:Interleukin-1 / Q000378:metabolism; D008562:Membrane Glycoproteins / Q000276:immunology; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology* / Q000378:metabolism; D060245:Tetraspanin 29; D014397:Tuberculosis, Pulmonary / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D015703:Antigens, CD; D000944:Antigens, Differentiation, B-Lymphocyte; D015415:Biomarkers; C064228:CD72 protein, human; D016827:CD8 Antigens; C554869:CD9 protein, human; D007375:Interleukin-1; D008562:Membrane Glycoproteins; D060245:Tetraspanin 29; D014409:Tumor Necrosis Factor-alpha