title: Chronic invasive fungal rhinosinusitis.
abstract: Chronic invasive fungal rhinosinusitis is an increasingly recognized, but inadequately characterized, disease entity which is separate and distinct from acute fulminant invasive fungal sinusitis and allergic fungal sinusitis. Chronic invasive fungal rhinosinusitis is divided into granulomatous and nongranulomatous subtypes based on histopathology, but the clinical distinction between the two subtypes is not clear. Current management includes varying degrees of surgical débridement and a prolonged course of antifungal agents. A protracted clinical course with recurrence after treatment is common.
authors.affiliation: Department of Otolaryngology, University of Florida College of Medicine, Gainesville, Florida 32610-0264, USA.
authors.forename: S P
authors.initials: SP
authors.lastname: Stringer
authors.forename: M W
authors.initials: MW
authors.lastname: Ryan
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012220:Rhinitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D012852:Sinusitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D014057:Tomography, X-Ray Computed
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B