title: Right ventricular diastolic filling assessed by conventional doppler and tissue Doppler imaging in normal children.
abstract: To examine age-related changes in right ventricular filling dynamics, we performed conventional pulsed Doppler (n=99) and tissue Doppler (n=30) echocardiographic studies in normal subjects aged 7 days to 273 months. The tricuspid flow velocity during early diastole (peak E) wave correlated significantly but weakly with the logarithm of age. The peak E wave in the early neonatal period was almost 80% of the older children's values and increased to 100% by 36 months of age. In the right ventricular tissue Doppler imaging, the peak myocardial velocity during early diastole also increased significantly with the logarithm of age. However, the tissue Doppler peak A did not change with age. There was a significant correlation between the tissue Doppler peak E wave and the tricuspid peak E wave and between the tissue Doppler peak E/A wave and the tricuspid peak E/A wave. The age-related changes in the tricuspid inflow velocity patterns were similar to the age-related alterations in the right ventricular myocardial velocity patterns. Age-related changes in the tricuspid inflow velocity and myocardial velocity patterns may be related to age-related maturation in the right ventricular diastolic performance.
authors.affiliation: Department of Pediatrics, Akita University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yasuoka
authors.forename: K
authors.initials: K
authors.lastname: Harada
authors.forename: T
authors.initials: T
authors.lastname: Orino
authors.forename: G
authors.initials: G
authors.lastname: Takada
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000375:Aging; D002648:Child; D002675:Child, Preschool; D003971:Diastole; D015150:Echocardiography, Doppler; D018619:Echocardiography, Doppler, Pulsed; D006321:Heart / Q000254:growth & development*; D006339:Heart Rate; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D012016:Reference Values; D012044:Regression Analysis; D016278:Ventricular Function, Right