Replication fork arrest and DNA recombination.
Replication arrests are associated with genome rearrangements, which result from either homologous or non-homologous recombination. Interestingly, proteins involved in homologous recombination are able to convert an arrested replication fork into a recombination intermediate, which promotes replication restart and thus presumably prevents genome rearrangements.
Michel
B
B
Laboratoire de Génétique Microbienne, Institut National de la Recherche Agronomique, 78352 Jouy en Josas Cedex, France. bmichel@biotec.jouy.inra.fr
D004265:DNA Helicases / Q000235:genetics; D004261:DNA Replication / Q000235:genetics*; D011995:Recombination, Genetic
D004265:DNA Helicases