title: [Syndrome of inappropriate macrophage activation associated with infantile visceral leishmaniasis].
abstract: Hemophagocytosis has already been in cases of visceral leishmaniasis and thus may complicate search for diagnosis. We report a case of hemophagocytosis in a 20 month-old boy presenting with fever, hepatosplenomegaly, pancytopenia and coagulopathy. An initial diagnosis of kala-azar was refuted because of absence of biological inflammatory syndrome and negativity of bone-marrow aspiration. Specific serology for visceral leishmaniasis become positive. The boy was given stibogluconate for 21 days; he improves gradually with complete remission.
authors.affiliation: Service de Pédiatrie, Hôpital Farhat Hached, Sousse.
authors.forename: F
authors.initials: F
authors.lastname: Thabet
authors.forename: B
authors.initials: B
authors.lastname: Tabarki
authors.forename: R
authors.initials: R
authors.lastname: Fehem
authors.forename: M
authors.initials: M
authors.lastname: Yacoub
authors.forename: H
authors.initials: H
authors.lastname: Selmi
authors.forename: A S
authors.initials: AS
authors.lastname: Essoussi
mesh_terms: D003937:Diagnosis, Differential; D015616:Histiocytosis, Non-Langerhans-Cell / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007223:Infant; D007898:Leishmaniasis, Visceral / Q000150:complications*; D008297:Male