title: Splenic littoral cell angioma in an infant.
abstract: A 1-year-old girl presented with fever, asthenia, and splenomegaly with hypersplenism. Abdominal ultrasound scan and magnetic resonance imaging showed multiple nodular cystic masses in an enlarged spleen. The histological examination of the resected spleen showed a novel type of vascular tumor called littoral cell angioma. The histopathologic and immunohistochemical features of this rare lesion are described. Distinction from other splenic vascular tumors is stressed because the clinical behavior of this new entity seems to be benign.
authors.affiliation: Department of Pathology, University Hospital, and School of Nursing, St John of God, University of Comillas, Ciempozuelos, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Antón-Pacheco
authors.forename: R M
authors.initials: RM
authors.lastname: Ayuso
authors.forename: I
authors.initials: I
authors.lastname: Cano
authors.forename: M A
authors.initials: MA
authors.lastname: Martinez
authors.forename: J
authors.initials: J
authors.lastname: Cuadros
authors.forename: F J
authors.initials: FJ
authors.lastname: Berchi
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006391:Hemangioma / Q000276:immunology / Q000473:pathology*; D006529:Hepatomegaly / Q000209:etiology; D006801:Humans; D007223:Infant; D013160:Splenic Neoplasms / Q000276:immunology / Q000473:pathology*; D013163:Splenomegaly / Q000209:etiology