Bladder cancer arising in a spina bifida patient.
We report the case of a 52-year-old patient with spina bifida, neurologic bladder, and a history of recurrent urinary tract infections (UTIs) in whom a bladder cancer was incidentally discovered. Cytology, cystoscopy, and cystography showed nonspecific, extensive inflammatory lesions. Cystography demonstrated a complex of diverticulae and cellules. Pathologic examination of a diverticulectomy specimen revealed a grade III pT3b transitional and squamous cell carcinoma. Because of the similar disease causation (recurrent UTIs, stones, and indwelling catheterization), we suggest extension of the guidelines proposed for patients with spinal cord injuries (ie, annual serial bladder biopsies) to patients with nontraumatic neurogenic bladder.
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Department of Urology, James Whitcomb Riley Hospital for Children, IndiSchool, Indianapolis, Indiana, USA.
Villers
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Malavaud
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Sarramon
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D002295:Carcinoma, Transitional Cell / Q000150:complications* / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D003556:Cystitis / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D011704:Pyelonephritis / Q000150:complications; D012307:Risk Factors; D016135:Spinal Dysraphism / Q000150:complications*; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D001750:Urinary Bladder, Neurogenic / Q000150:complications*; D014549:Urinary Incontinence / Q000150:complications / Q000601:surgery; D014552:Urinary Tract Infections / Q000150:complications