False negative conventional histology of lymph nodes in patients with head and neck cancer.
Lymph node micrometastases in patients with head and neck cancer found node-negative by clinical examination and conventional histology may be discovered with additional sectioning of the lymph nodes, by immunohistochemistry and by molecular biology.
Ferlito
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Department of Otolaryngology, Head and Neck Surgery, University of Udine, Italy. clorl@dsc.uniud.it
Rinaldo
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D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005188:False Negative Reactions; D016158:Genes, p53; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000175:diagnosis; D011379:Prognosis; D020133:Reverse Transcriptase Polymerase Chain Reaction