Angiomatoid (malignant) fibrous histiocytoma as a second tumour in a child with neuroblastoma.
Neuroblastoma occurring as a disseminated disease in children has a poor prognosis. Haematogenous metastases usually involve the marrow, bone, liver and skin. A second neoplasm may also develop. We describe a child with retroperitoneal neuroblastoma (stage 3) who developed a nodular mass in the inguinal area which was suspected to be a metastasis. Histopathology disclosed an angiomatoid (malignant) fibrous histiocytoma, and excision was curative. The occurrence of angiomatoid (malignant) fibrous histiocytoma as a second tumour in a patient with neuroblastoma has not previously been reported.
Gambini
C
C
Departments of Pathology and Paediatric Hematology/Oncology, G. Gaslini Institute and DISEM, Section of Dermatology, University of Genoa, Genoa, Italy.
Haupt
R
R
Rongioletti
F
F
D000008:Abdominal Neoplasms / Q000601:surgery* / Q000648:ultrastructure; D002648:Child; D018219:Histiocytoma, Benign Fibrous / Q000601:surgery* / Q000648:ultrastructure; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000601:surgery* / Q000648:ultrastructure; D009447:Neuroblastoma / Q000628:therapy*; D012186:Retroperitoneal Neoplasms / Q000628:therapy*