title: Anatomical risk factors for proximal perigraft endoleak and graft migration following endovascular repair of abdominal aortic aneurysms.
abstract: BACKGROUND
  proximal perigraft endoleak (PPE) and graft migration are associated with significant morbidity and mortality. Objective data establishing correlation between neck anatomy and these complications are lacking. The aim of this study was to analyse the anatomy of the neck in order to find which variables were significantly associated with PPE and graft migration.
  
  
  METHODS
  one hundred and eighty-four patients underwent endovascular repair (EVR) of infrarenal AAA using an in-house custom-made stent graft (Gianturco stents plus Dacron). Thirty-one patients had PPE and fifteen had graft migration. Neck diameter was measured at the level of renal arteries and lower limit of the neck. Necks were classified according to shape. Neck angulation was measured from spiral computed tomography (CT) or magnetic resonance imaging (MRI) reconstructions, or angiograms. Thrombus or atheroma lining and presence of calcifications were recorded.
  
  
  RESULTS
  neck angulation was significantly greater in patients who had PPE (50+/-16, p=0. 0005) or graft migration (54+/-20, p=0.003), compared to patients who had none of these two complications (37+/-18). Neck diameter was significantly greater in patients with PPE (p=0.05). Incidence of PPE or graft migration was not significantly higher in the presence of a conical shape, thrombus or atheroma lining and calcifications.
  
  
  CONCLUSIONS
  neck angulation was the risk factor most significantly related to PPE and graft migration.
authors.affiliation: Vascular and Endovascular Surgery Department, Queen's Medical Centre, Nottingham, UK.
authors.forename: J
authors.initials: J
authors.lastname: Albertini
authors.forename: S
authors.initials: S
authors.lastname: Kalliafas
authors.forename: S
authors.initials: S
authors.lastname: Travis
authors.forename: S W
authors.initials: SW
authors.lastname: Yusuf
authors.forename: J A
authors.initials: JA
authors.lastname: Macierewicz
authors.forename: S C
authors.initials: SC
authors.lastname: Whitaker
authors.forename: N M
authors.initials: NM
authors.lastname: Elmarasy
authors.forename: B R
authors.initials: BR
authors.lastname: Hopkinson
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects*; D000792:Angiography; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D001018:Aortic Diseases / Q000150:complications; D001161:Arteriosclerosis / Q000150:complications; D001672:Biocompatible Materials; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D002114:Calcinosis / Q000150:complications; D016009:Chi-Square Distribution; D005548:Foreign-Body Migration / Q000209:etiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D015588:Observer Variation; D011093:Polyethylene Terephthalates; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012307:Risk Factors; D016037:Single-Blind Method; D015607:Stents / Q000009:adverse effects*; D013499:Surface Properties; D013927:Thrombosis / Q000150:complications; D014057:Tomography, X-Ray Computed
chemical_list: D001672:Biocompatible Materials; D011093:Polyethylene Terephthalates