[Preventive effect of gubao on hydrocortisone-induced osteoporosis in rats].
The antagonistic effect of Gubao (consisting of Herba Epimedii, Radix Astragali, etc.) on hydrocortisone-induced osteoporosis in rats was observed in quantitative bone histomorphometry study with stereological method. The results of experiment show that Gubao helps to reduce trbecular bone resorption and increase bone formation in ratsuith hydrocortisone-induced osteoporosis. It is suggested that Gubao is useful in preventing glucocorticoid-induced osteoporosis.
Xie
H
H
Guangdong Medical College, Zhanjiang.
Wu
T
T
Huang
L
L
Li
C
C
D000818:Animals; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006854:Hydrocortisone; D008297:Male; D010024:Osteoporosis / Q000139:chemically induced / Q000517:prevention & control*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013977:Tibia / Q000473:pathology
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D006854:Hydrocortisone