Young adults with Down's syndrome show increased corticotrope responsiveness to hCRH or hexarelin, a peptidyl GH secretagogue.
Ramunni
J
J
Department of Internal Medicine, University of Turin, Troina, Italy.
Ragusa
L
L
Arvat
E
E
Gianotti
L
L
Maccagno
B
B
Giordano
R
R
Pettinato
R
R
Barone
C
C
Romano
C
C
Ghigo
E
E
D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000097:blood / Q000378:metabolism; D003346:Corticotropin-Releasing Hormone / Q000494:pharmacology*; D004314:Down Syndrome / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008875:Middle Aged; D009842:Oligopeptides / Q000494:pharmacology*; D010903:Pituitary Gland, Anterior / Q000187:drug effects* / Q000378:metabolism* / Q000473:pathology
D009842:Oligopeptides; C086184:hexarelin; D000324:Adrenocorticotropic Hormone; D003346:Corticotropin-Releasing Hormone; D006854:Hydrocortisone