Preferential segregation of marker chromosomes 14 and 18 in mouse recombinant inbred strains derived from the KE and CBA/Kw strains.
The segregation pattern of chromosomes 14 and 18 were analyzed in recombinant inbred strains of mice developed from KE and CBA/Kw strains. The analysis was possible owing to the fact that the C-band on chromosomes 14 of the CBA/Kw strain and that of chromosome 18 of the KE strain show size polymorphism: while the CBA/Kw mice have a small sized C-band on chromosome 14, the KE mice show small C-bands on chromosome 18. Chromosomes were identified by G-banding and FISH. The results show that the chromosomes with small centromeric chromatin segregate preferentially.
Lenartowicz
M
M
Department of Genetics and Evolution, Jagiellonian University, Kraków, Poland. Lena@zuk.iz.uj.edu.pl
Wójcik
A
A
D000818:Animals; D002871:Chromosome Banding; D020090:Chromosome Segregation / Q000235:genetics*; D007178:Inbreeding; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics*