[Effect of Yang-warming and Qi-tonifying natural products on neuroendocrine of deficiency-cold rats].
The rat fed with the compound drug Zhi Mu and Shi Gao was made into an animal model of deficiency cold syndrome. The deficiency cold state was kept for more than 7 days after stopping the drug. So the animal model is good for studing the therapeutic effect of products of heat nature. After 3 therapeutic days with Fu Jiang and Shen Qi compounds, the D beta H activity in serum, cortisone in adrenal gland and NE, DA amount in brain were increased, but serotonin was decreased, and after 7 days the effect was increased significantly. Both compounds could excite the sympathetic nerve and endocrine system in the peripheral and central nervous systems. Shen Qi compound acts quickly, but does not last as long as Fu Jiang. The effect will be better if the two compounds are used together.
Song
H
H
Department of Integrated Chinese and Western Medicine, Beijing Medical University.
Liang
Y
Y
D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism*; D003348:Cortisone / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism; D004299:Dopamine beta-Hydroxylase / Q000097:blood*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D009490:Neurosecretory Systems / Q000187:drug effects; D009638:Norepinephrine / Q000378:metabolism*; D019413:Qi; D051381:Rats; D012701:Serotonin / Q000378:metabolism; D016711:Yang Deficiency / Q000378:metabolism*
D004365:Drugs, Chinese Herbal; D012701:Serotonin; D004299:Dopamine beta-Hydroxylase; D003348:Cortisone; D004298:Dopamine; D009638:Norepinephrine