Worse six-month outcome for patients with multiple stents in a single coronary artery.
BACKGROUND
Before the "era" of optimal stent deployment, very few data concerning multiple stents in a single coronary artery showed restenosis rates up to 60%.


OBJECTIVE
To evaluate the 6-month outcome of patients receiving multiple Palmaz-Schatz stents (> or =2 stents) in a single coronary artery compared to those receiving single stents.


METHODS
Three hundred and forty-eight patients having multiple stents were compared to 174 patients receiving single stents during a 6-month follow-up.


RESULTS
Repeat target lesion revascularization (RTLR), either repeat PTCA or CABG, was 10.4% in the single-stent group, 22.6% in the two-stent group, and 23.1% in the > or =2 stent group (p = 0.001, single versus 2 or > or =2 stents). There was not a significant difference between single stent and multiple stent groups in myocardial infarction and death during 6-month follow-up. Multivariate analysis showed multiple stents, diabetes mellitus, and type C lesion to be predictors of RTLR.


CONCLUSIONS
Placement of two or more stents was associated with a significantly higher RTLR compared with single stent placement. The optimal approach to diffuse coronary artery disease remains to be defined.
Gaxiola
E
E
Watson Clinic LLP, Lakeland, Florida.
Vlietstra
R E
RE
Browne
K F
KF
Ebersole
D G
DG
Brenner
A S
AS
Weeks
T T
TT
Mines
M H
MH
Roman
L
L
Kerensky
R A
RA
D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects* / Q000401:mortality; D001026:Coronary Artery Bypass; D023903:Coronary Restenosis / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology / Q000628:therapy; D012086:Reoperation; D015607:Stents / Q000009:adverse effects*; D013997:Time Factors; D016896:Treatment Outcome