Aspergillus fumigatus isolated from blood samples of a patient with pulmonary aspergilloma after embolization.
Aspergillus DNA was detected by PCR in the serum sample of a 78-year-old man and galactomannan antigen of Aspergillus by sandwich ELISA was found. However, the infiltrative hyphae were not detected by the histopathologic examination of the lung. He developed hemoptysis, which required embolization of bronchial arteries. Aspergillus fumigatus was isolated from blood samples after embolization by the lysis centrifugation method. To our knowledge, this is probably the first case in which Aspergillus spp. has been isolated from the systemic circulatory blood in a patient with pulmonary aspergilloma after embolization.
Seki
M
M
Second Department of Internal Medicine, Nagasaki University School of Medicine.
Maesaki
S
S
Hashiguchi
K
K
Tomiyama
Y
Y
Tomono
K
K
Tashiro
T
T
Kohno
S
S
D000368:Aged; D000907:Antibodies, Bacterial / Q000032:analysis; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D001232:Aspergillus fumigatus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000032:analysis; D003937:Diagnosis, Differential; D004621:Embolization, Therapeutic; D004797:Enzyme-Linked Immunosorbent Assay; D016469:Fungemia; D006469:Hemoptysis / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008172:Lung Diseases, Fungal / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D016133:Polymerase Chain Reaction; D014057:Tomography, X-Ray Computed
D000907:Antibodies, Bacterial; D000935:Antifungal Agents; D004269:DNA, Bacterial; D017964:Itraconazole