A new family with Papillon-Lefèvre syndrome: effectiveness of etretinate treatment.
Papillon-Lefèvre syndrome is characterized by the association of palmoplantar hyperkeratosis, severe periodontitis, and early loss of deciduous and permanent teeth. We report two patients from the same family, aged 21 and 30 years, who were unaware of their pathology; one was successfully treated with etretinate.
Siragusa
M
M
Department of Pediatrics, Oasi Institute for Research on Mental Retardation and Brain Aging, Troina, Italy.
Romano
C
C
Batticane
N
N
Batolo
D
D
Schepis
C
C
D000328:Adult; D005050:Etretinate / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008297:Male; D010214:Papillon-Lefevre Disease / Q000188:drug therapy* / Q000235:genetics* / Q000473:pathology; D010375:Pedigree; D016896:Treatment Outcome
D007641:Keratolytic Agents; D005050:Etretinate