title: [Reduction of nitro-substituted compounds by native and immobilized Escherichia coli cells].
abstract: Reduction of nitro-substituted compounds, 1,4-benzodiazepine-2-ones, dibenzo[b,f]-1,4-diazepines, quinolones, and quinoxalinones, by Escherichia coli cells was studied. Physicochemical methods demonstrated the formation of corresponding amines. 4-(p-Nitrophenyl)-1H-6-R-quinolones-2 were nor reduced by Escherichia coli cells. Regiospecific reduction of 2,4-dinitro-5H-11-(p-R-phenyl)-dibenzo[b,f]-1,4-diazepines and 4-(2'-R-3',5'-dinitro)-benzoyl-3,4-dihydroquinoxalinones-2 was shown to result in the formation of 2-nitro-4-amino-5H-11-(p-R-phenyl)-dibenzo[b,f]-1,4-diazepines and 4-(2'-R-3'-nitro-5'-amino)-benzoyl-3,4-dihydroquinoxalinones-2, respectively. Methods for microbiological reduction of nitro compounds and immobilization of Escherichia coli cells into carrageenan and its modified forms were elaborated.
authors.affiliation: Bogatskii Physicochemical Institute, National Academy of Sciences of Ukraine, Odessa, Ukraine.
authors.forename: T I
authors.initials: TI
authors.lastname: Davidenko
authors.forename: G I
authors.initials: GI
authors.lastname: Bondarenko
mesh_terms: D018914:Cells, Immobilized / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism*; D009574:Nitro Compounds / Q000378:metabolism*; D010084:Oxidation-Reduction
chemical_list: D009574:Nitro Compounds