title: Effect of Trypanosoma lewisi (Kinetoplastida: Trypanosomatidae) on the infection of white rats with Toxoplasma gondii (Eucoccidia: Sarcocystidae) oocysts.
abstract: White rats were inoculated with 10(6) trypomastigotes of Trypanosoma lewisi, simultaneously or two days before and after inoculation with 10(5) oocysts of T. gondii. A greater number of cysts was found in the brain of the animals having concomitant inoculations, as compared with rats inoculated with either one of the two parasites. An apparent immunosuppressive effect is likely. Since both organisms can be found in rats, it is possible that infections with T. lewisi, could make this rodent another intermediate host for Toxoplasma infections.
authors.affiliation: Instituto de Acueductos y Alcantarillados, Universidad de Costa Rica, San José, Costa Rica.
authors.forename: G
authors.initials: G
authors.lastname: Catarinella Arrea
authors.forename: M
authors.initials: M
authors.lastname: Chinchilla Carmona
authors.forename: O M
authors.initials: OM
authors.lastname: Guerrero Bermúdez
authors.forename: E
authors.initials: E
authors.lastname: Abrahams
mesh_terms: D000818:Animals; D001927:Brain Diseases / Q000276:immunology / Q000469:parasitology*; D004199:Disease Vectors; D007108:Immune Tolerance; D051381:Rats; D017208:Rats, Wistar; D014122:Toxoplasma / Q000276:immunology*; D014124:Toxoplasmosis, Animal / Q000276:immunology / Q000469:parasitology*; D014350:Trypanosoma lewisi / Q000276:immunology*; D014352:Trypanosomiasis / Q000276:immunology / Q000469:parasitology*