title: Lidocaine toxicity secondary to postoperative bladder instillation in a pediatric patient.
abstract: The intravesical use of local anesthetics has been described for a variety of urologic procedures with no previous reports of toxicity. We recently took care of a 2.5- year-old girl with systemic lidocaine toxicity following treatment for postoperative bladder spasms. The patient developed a generalized seizure requiring endotracheal intubation but recovered fully with supportive care. We report the clinical details of this case as well as a brief review of lidocaine toxicity.
authors.affiliation: Department of Pediatrics, Naval Medical Center San Diego, San Diego, California 92134-5000, USA.
authors.forename: C R
authors.initials: CR
authors.lastname: Clapp
authors.forename: W B
authors.initials: WB
authors.lastname: Poss
authors.forename: B G
authors.initials: BG
authors.lastname: Cilento
mesh_terms: D000283:Administration, Intravesical; D000777:Anesthetics / Q000009:adverse effects*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000009:adverse effects*; D011183:Postoperative Complications / Q000188:drug therapy*; D012640:Seizures / Q000139:chemically induced*; D013035:Spasm / Q000188:drug therapy* / Q000209:etiology; D001745:Urinary Bladder Diseases / Q000188:drug therapy* / Q000209:etiology; D013520:Urologic Surgical Procedures / Q000009:adverse effects
chemical_list: D000777:Anesthetics; D008012:Lidocaine