Castleman's disease of the left triceps in a child suspected to be a small round cell tumor of childhood.
Castleman's disease (CD) is histologically characterized by a proliferation of polyclonal small lymphocytes and plasma cells. The clinical presentation varies widely, but most commonly manifests as a solitary mediastinal mass, incidentally found on radiographic examination. We present a case of a 10-year-old girl who exhibited a left arm mass which, preoperatively and on frozen section, was diagnosed as a small round cell tumor of childhood (SRCT). This report emphasizes the unusual location of CD in the soft tissue and as a rare entity to be considered in the differential diagnosis of SRCT.
Fiel-Gan
M D
MD
Department of Pathology, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102, USA.
Voytek
T M
TM
Weiss
R G
RG
Brown
R T
RT
Joshi
V V
VV
D001132:Arm; D005871:Castleman Disease / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis; D008214:Lymphocytes / Q000473:pathology; D008279:Magnetic Resonance Imaging; D018482:Muscle, Skeletal / Q000473:pathology*