Superoxide dismutase reduces susceptibility to metronidazole of the pathogenic protozoan Entamoeba histolytica under microaerophilic but not under anaerobic conditions.
Wassmann
C
C
Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Str. 74, Hamburg, 20359, Germany.
Bruchhaus
I
I
D000332:Aerobiosis; D000693:Anaerobiosis; D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology*; D004351:Drug Resistance; D004748:Entamoeba histolytica / Q000187:drug effects* / Q000201:enzymology* / Q000472:pathogenicity; D015870:Gene Expression; D008795:Metronidazole / Q000494:pharmacology*; D010544:Peroxidases / Q000235:genetics / Q000378:metabolism; D054464:Peroxiredoxins; D013482:Superoxide Dismutase / Q000235:genetics / Q000378:metabolism*; D014162:Transfection
D000890:Anti-Infective Agents; D008795:Metronidazole; D010544:Peroxidases; D054464:Peroxiredoxins; D013482:Superoxide Dismutase