Synthesis of 2-substituted 3-nitro-1,2-dihydropyridines by heterocyclic annulation reactions of a sec-nitrodienamine with aldehyde compounds.
The reaction of a sec-nitrodienamine 3 with aldehyde compounds afforded 2-substituted 3-nitro-1,2-dihydropyridines 5, providing a heterocyclic annulation reaction.
Koike
T
T
Showa Pharmaceutical University, Machida, Tokyo, Japan.
Shinohara
Y
Y
Ishibashi
N
N
Takeuchi
N
N
Tobinaga
S
S
D000447:Aldehydes / Q000737:chemistry*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009574:Nitro Compounds / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis*; D013055:Spectrophotometry, Infrared
D000447:Aldehydes; D007202:Indicators and Reagents; D009574:Nitro Compounds; D011725:Pyridines