[Influence of intercellular adhesion molecule-1 transcription on nasal epithelial cell by airborne allergenic pollens].
Eleven patients with Artemisia allergic rhinitis were evaluated. Among them 8 were studied during pollen season and 3 out of pollen season. Intercellular adhesion molecule-1(ICAM-1) was detected on nasal epithelial cells by reverse transcription polymerase chain reaction (RT-PCR). The results showed that ICAM-1 was detectable from all samples in the pollen season. However, during off-pollen season 2 of the 3 samples were negative, 1 was positive (who was also positive to house dust). It is suggested that ICAM-1 is detectable on nasal epithelial cells during exposure to specific allergen.
Wang
L
L
First Hospital, Shanxi Medical University, Taiyuan.
Fan
W
W
Yin
L
L
D000293:Adolescent; D000328:Adult; D004847:Epithelial Cells / Q000378:metabolism*; D005260:Female; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000096:biosynthesis* / Q000235:genetics; D008297:Male; D009297:Nasal Mucosa / Q000378:metabolism* / Q000473:pathology; D016133:Polymerase Chain Reaction / Q000379:methods; D012333:RNA, Messenger / Q000235:genetics; D006255:Rhinitis, Allergic, Seasonal / Q000378:metabolism* / Q000473:pathology
D012333:RNA, Messenger; D018799:Intercellular Adhesion Molecule-1