[Vibrissectomy in rats in early ontogeny leads to disordered functional properties of the cortical projection neurons].
Vibrissae trimming during the first 20 days of postnatal life caused alternations of the properties of the receptive fields of single neurons in the barrel-field cortex in rats. The following changes were found in the deafferented cortex: (i) an extension of the receptive fields of single neurons as judged from an increase in the number of vibrissae with short-latency excitatory responses to stimulation and (ii) a depression of the inhibitory receptive field tuning mechanisms.
Sitnikova
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Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow.
D000818:Animals; D000831:Animals, Newborn; D002540:Cerebral Cortex / Q000502:physiology*; D016009:Chi-Square Distribution; D003714:Denervation; D009474:Neurons / Q000502:physiology*; D010812:Physical Stimulation; D051381:Rats; D017208:Rats, Wistar; D011930:Reaction Time / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D018709:Statistics, Nonparametric; D014738:Vibrissae / Q000294:innervation / Q000502:physiology*