Cell surface receptors.
During the past year, the database of ligand-receptor complexes has essentially doubled. These new results have immeasurably extended and expanded our view of cell surface receptor structure and function. The flood of data has revealed new models for receptor cross-linking, demonstrating the potential stringency of the extracellular requirements for the initiation of intracellular signalling and highlighting unexpected interactions suggestive of higher order clustering.
Deller
M C
MC
CRC Receptor Structure Group, Wellcome Trust Centre for Human Genetics, Headington, OX3 7BN, UK. Marc.Deller@strubi.ox.ac.uk
Yvonne Jones
E
E
D000818:Animals; D017209:Apoptosis / Q000502:physiology; D001665:Binding Sites; D015815:Cell Adhesion Molecules / Q000737:chemistry / Q000502:physiology; D016207:Cytokines / Q000737:chemistry / Q000378:metabolism; D006133:Growth Substances / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D007501:Iron / Q000378:metabolism; D008024:Ligands; D008958:Models, Molecular; D011485:Protein Binding; D011956:Receptors, Cell Surface / Q000737:chemistry / Q000145:classification / Q000502:physiology; D018121:Receptors, Cytokine / Q000737:chemistry / Q000378:metabolism; D017978:Receptors, Growth Factor / Q000737:chemistry / Q000378:metabolism; D011971:Receptors, Immunologic / Q000737:chemistry / Q000502:physiology; D011991:Receptors, Virus / Q000737:chemistry / Q000378:metabolism; D015398:Signal Transduction; D013698:Templates, Genetic
D015815:Cell Adhesion Molecules; D016207:Cytokines; D006133:Growth Substances; D008024:Ligands; D011956:Receptors, Cell Surface; D018121:Receptors, Cytokine; D017978:Receptors, Growth Factor; D011971:Receptors, Immunologic; D011991:Receptors, Virus; D007501:Iron