[Human herpesviruses 6 and 7 (HHV-6 and HHV-7)].
Human herpesviruses 6 (HHV-6) and 7 (HHV-7) are world wide T lymphotropic viruses recently discovered. Their transmission is essentially by salivary route. Primary infections which occurred early in infancy, respectively during the first year of life for HHV-6 and in the second or third year for HHV-7, are followed by latency for life. HHV-7 is not actually associated with a disease. HHV-6 primary infection is often asymptomatic, if not it can induce exanthem subitum. HHV-6 reactivation can be symptomatic in immunodeficient subjects. The role of HHV-6 in the arising of lymphoproliferative or auto-immune diseases, discussed for a long time, is still to elucidate. HHV-6 infection is diagnosed by serodiagnosis in case of primary infection, but in the great number of cases, it would be realized by polymerases chain reaction.
Ranger-Rogez
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Laboratoire de virologie CHU Dupuytren, Limoges.
Venot
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Denis
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D002675:Child, Preschool; D004279:DNA, Viral / Q000032:analysis; D003937:Diagnosis, Differential; D006566:Herpesviridae Infections / Q000175:diagnosis / Q000276:immunology / Q000473:pathology*; D015654:Herpesvirus 6, Human / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity*; D016199:Herpesvirus 7, Human / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity*; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D007231:Infant, Newborn; D016133:Polymerase Chain Reaction; D011379:Prognosis
D004279:DNA, Viral