title: [Characteristics of the acute phase reaction in humans with various types of autonomic nervous system regulation during simulated hyperthermia].
abstract: Depending on the type of autonomous regulation, differences in basic levels of interleukin-1 beta (IL-1 beta) and tumor necrosis factor alpha (TNF alpha) were revealed under conditions of hyperthermia in healthy subjects aged 19-21. A parasympathetic type of autonomous regulation corresponded to higher initial levels of proinflammatory cytokinesis, whereas a dominating sympathetic type corresponded to lower levels of the IL-1 beta and TNF alpha. The subjects with the latter type of regulation revealed an increase in the IL-1 beta TNF alpha combined with a higher heat tolerance. The subjects with the former type of regulation revealed a lower heat tolerance. The increase in the alpha2-macroglobulin appeared to be a most typical acute phase response of the human body to hyperthermia.
authors.affiliation: Military Medical Academy and Pavlov State Medical University, 197022, St. Petersburg, L. Tolstoy St. 6/8, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Bannikov
authors.forename: V V
authors.initials: VV
authors.lastname: Dorofeĭkov
authors.forename: T S
authors.initials: TS
authors.lastname: Freĭdlin
authors.forename: I S
authors.initials: IS
authors.lastname: Freĭdlin
authors.forename: E B
authors.initials: EB
authors.lastname: Shustov
authors.forename: I G
authors.initials: IG
authors.lastname: Shcherbak
authors.forename: D Iu
authors.initials: DIu
authors.lastname: Iastrebov
mesh_terms: D000209:Acute-Phase Proteins / Q000096:biosynthesis; D000210:Acute-Phase Reaction; D000328:Adult; D001341:Autonomic Nervous System / Q000502:physiology*; D001794:Blood Pressure; D001831:Body Temperature; D005080:Exercise Test; D006339:Heart Rate; D006358:Hot Temperature; D006801:Humans; D007375:Interleukin-1 / Q000096:biosynthesis; D008297:Male; D010275:Parasympathetic Nervous System / Q000502:physiology; D013564:Sympathetic Nervous System / Q000502:physiology; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis
chemical_list: D000209:Acute-Phase Proteins; D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha