A chemically intelligent antimicrobial coating for urologic devices.
Contact biocides are a relatively new form of infection-resistant materials. Surfacine is a silver based antimicrobial coating that can be immobilized on the surface of most alloplastic materials used to fabricate devices. It exhibits broad-spectrum antimicrobial activity exclusively at the surface without elution and does not induce antimicrobial activity in contacting fluids such as urine regardless of volume. Because it is permanently immobilized on the material surface, the coating is nontoxic to cells and is not anticipated to exhibit immunogenicity, teratogenicity, or carcinogenicity.
Subramanyam
S
S
Intelligent Biocides, LLC, Tewksbury, Massachusetts 01876, USA. sundar@ibhome.com
Yurkovetsiky
A
A
Hale
D
D
Sawan
S P
SP
D000890:Anti-Infective Agents; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D006801:Humans; D016459:Prosthesis-Related Infections / Q000517:prevention & control*; D014572:Urology / Q000295:instrumentation*
D000890:Anti-Infective Agents; D020099:Coated Materials, Biocompatible