The suckling mouse model of cholera.
Vibrio cholerae colonization of the suckling mouse intestine is a commonly used animal model for the human diarrheal disease cholera. This model has a number of advantages as well as disadvantages, and has been extremely useful in the identification and characterization of proven and putative virulence factors involved in human cholera.
Klose
K E
KE
Dept. of Microbiology, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78284-7758, USA. klose@uthscsa.edu
D000818:Animals; D000831:Animals, Newborn; D000833:Animals, Suckling; D002771:Cholera / Q000382:microbiology / Q000401:mortality / Q000473:pathology; D004195:Disease Models, Animal; D004198:Disease Susceptibility; D006801:Humans; D007422:Intestines / Q000382:microbiology / Q000473:pathology; D051379:Mice; D014734:Vibrio cholerae / Q000235:genetics / Q000472:pathogenicity* / Q000502:physiology*; D014774:Virulence