Influence of adrenal cortex on testicular activity in the toad during the breeding season.
The aim of the present study was to determine the role of adrenals in gonadal activity in the male toad during the breeding season. Exogenous administration of corticosterone or metapyrone for 6 days inhibited adrenal delta5-3beta(delta 5-3 beta) hydroxysteroid (delta5-3beta-HSD) and testicular 17beta (17 beta) hydroxysteroid dehydrogenase (17beta-HSD) activities, decreased the serum levels of testosterone and inhibited spermatogenesis. When toads were treated with corticosterone a significant rise of serum corticosterone was noted while metapyrone treatment appeared to decrease serum corticosterone levels. It is concluded that adrenocortical hormone plays an indirect role in testicular activity in toads during the breeding season.
Biswas
N M
NM
Department of Physiology, University College of Science and Technology, Calcutta, India.
Chaudhuri
G R
GR
Sarkar
M
M
Sengupta
R
R
D015096:3-Hydroxysteroid Dehydrogenases / Q000378:metabolism; D000302:Adrenal Cortex / Q000502:physiology*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002025:Bufonidae; D003345:Corticosterone / Q000097:blood / Q000494:pharmacology; D008297:Male; D011725:Pyridines / Q000494:pharmacology; D012098:Reproduction; D012621:Seasons; D013091:Spermatogenesis / Q000187:drug effects; D013737:Testis / Q000502:physiology*; D013739:Testosterone / Q000097:blood
D011725:Pyridines; C013109:metapyrone; D013739:Testosterone; D015096:3-Hydroxysteroid Dehydrogenases; D003345:Corticosterone