Scleroma of the larynx and associated squamous cell carcinoma: a causal relationship?
The known risk factors for development of laryngeal carcinoma are smoking, alcohol drinking, air pollution, laryngeal keratosis, single adult papillomas, and previous irradiation. Laryngeal scleroma as a risk factor for the development of laryngeal carcinoma has not been mentioned in the English-language literature, to my knowledge. This is a report of 2 cases of proven long-term rhinolaryngoscleroma that have changed to laryngeal carcinoma.
Abou El-Hamd
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KA
Department of Otolaryngology, Sohag Medical School, South Valley University, Egypt.
D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D007818:Laryngeal Diseases / Q000150:complications* / Q000532:radiotherapy / Q000601:surgery; D007822:Laryngeal Neoplasms / Q000209:etiology* / Q000532:radiotherapy / Q000601:surgery; D007825:Laryngectomy / Q000379:methods; D008297:Male