title: Serovars of Mycobacterium avium complex isolated from AIDS and non-AIDS patients in Spain.
abstract: Antigen fingerprinting based on surface glycolipid antigens was applied to the epidemiology of clinical isolates of the Mycobacterium avium complex from 128 acquired immunodeficiency syndrome (AIDS) and 31 non-AIDS patients from several different regions of Spain. The application of thin-layer chromatography, gas chromatography-mass spectrometry and monoclonal antibodies, combined with ELISA, allowed a facile identification, differentiation and classification of the isolates. The cumulative results demonstrate that, among the clinical isolates, serovar 4 was predominant in both AIDS (33.6%) and non-AIDS (22.6%) isolates. In general, the results demonstrate geographical as well as disease-related differences in the distribution of Myco. avium complex serovars of clinical importance.
authors.affiliation: Servei de Microbiología, Hospital Universitari Germans Trias i Pujol de Badalona, Facultat de Medicina de la Universitat Autònoma de Barcelona, Spain. jtorrell@cvmbs.colostate.edu
authors.forename: J B
authors.initials: JB
authors.lastname: Torrelles
authors.forename: D
authors.initials: D
authors.lastname: Chatterjee
authors.forename: J G
authors.initials: JG
authors.lastname: Lonca
authors.forename: J M
authors.initials: JM
authors.lastname: Manterola
authors.forename: V R
authors.initials: VR
authors.lastname: Ausina
authors.forename: P J
authors.initials: PJ
authors.lastname: Brennan
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002855:Chromatography, Thin Layer; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D015269:Mycobacterium avium Complex / Q000145:classification* / Q000254:growth & development / Q000302:isolation & purification*; D015270:Mycobacterium avium-intracellulare Infection / Q000382:microbiology*; D013030:Spain