title: Pyrrolidine inhibitors of human cytosolic phospholipase A(2).
authors.affiliation: Shionogi Research Laboratories, Shionogi & Company, Ltd., 12-4, Sagisu 5-chome, Fukushima-ku, Osaka 553-0002, Japan. kaoru.seno@shionogi.co.jp
authors.forename: K
authors.initials: K
authors.lastname: Seno
authors.forename: T
authors.initials: T
authors.lastname: Okuno
authors.forename: K
authors.initials: K
authors.lastname: Nishi
authors.forename: Y
authors.initials: Y
authors.lastname: Murakami
authors.forename: F
authors.initials: F
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Matsuura
authors.forename: M
authors.initials: M
authors.lastname: Wada
authors.forename: Y
authors.initials: Y
authors.lastname: Fujii
authors.forename: M
authors.initials: M
authors.lastname: Yamada
authors.forename: T
authors.initials: T
authors.lastname: Ogawa
authors.forename: T
authors.initials: T
authors.lastname: Okada
authors.forename: H
authors.initials: H
authors.lastname: Hashizume
authors.forename: M
authors.initials: M
authors.lastname: Kii
authors.forename: S
authors.initials: S
authors.lastname: Hara
authors.forename: S
authors.initials: S
authors.lastname: Hagishita
authors.forename: S
authors.initials: S
authors.lastname: Nakamoto
authors.forename: K
authors.initials: K
authors.lastname: Yamada
authors.forename: Y
authors.initials: Y
authors.lastname: Chikazawa
authors.forename: M
authors.initials: M
authors.lastname: Ueno
authors.forename: I
authors.initials: I
authors.lastname: Teshirogi
authors.forename: T
authors.initials: T
authors.lastname: Ono
authors.forename: M
authors.initials: M
authors.lastname: Ohtani
mesh_terms: D002460:Cell Line; D003600:Cytosol / Q000201:enzymology; D015232:Dinoprostone / Q000096:biosynthesis; D015777:Eicosanoids / Q000096:biosynthesis; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D017997:Leukotriene C4 / Q000096:biosynthesis; D010741:Phospholipases A / Q000037:antagonists & inhibitors*; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D015777:Eicosanoids; D004791:Enzyme Inhibitors; D011759:Pyrrolidines; D017997:Leukotriene C4; D010741:Phospholipases A; D015232:Dinoprostone