title: Phytosorbent prepared from sunflower seed husks prevents mercuric chloride accumulation in kidney and muscle of adult rabbits.
abstract: In the present study, the effect of a melanin-containing phytosorbent, "Victoria," on mercury accumulation in rabbits' tissues was studied. This phytosorbent is derived from black sunflower seed husks. Domestic rabbits were administered either one single nontoxic low-level dose of mercuric chloride (i.e., 50 microg/1 kg body weight [control group]) or combinations of mercury and the phytosorbent "Victoria" (i.e., experimental group). Mercury and phytosorbent were administered per os daily for 12 d. Mercury in tissues was determined by cold-vapor atomic absorption spectroscopy. Mercury in kidney and muscle of the experiment group was, on average, 25.8 and 4.7 times less, respectively, than in the control group. The authors concluded that the phytosorbent prevented accumulation of mercury in the kidney and muscle tissues and exerted a protective effect against mercury toxicity.
authors.affiliation: Institute of Physics, National Academy of Sciences of Belarus, Minsk.
authors.forename: V A
authors.initials: VA
authors.lastname: Lapina
authors.forename: P M
authors.initials: PM
authors.lastname: Sheshko
authors.forename: E A
authors.initials: EA
authors.lastname: Pankovets
authors.forename: A E
authors.initials: AE
authors.lastname: Dontsov
mesh_terms: D000042:Absorption / Q000187:drug effects; D000284:Administration, Oral; D000818:Animals; D002614:Chelating Agents / Q000494:pharmacology*; D006368:Helianthus; D007668:Kidney / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008627:Mercuric Chloride / Q000493:pharmacokinetics*; D009132:Muscles / Q000378:metabolism*; D011817:Rabbits; D012639:Seeds; D014018:Tissue Distribution / Q000187:drug effects
chemical_list: D002614:Chelating Agents; D008627:Mercuric Chloride