Successful transplantation of a cadaveric kidney with post-infectious glomerulonephritis.
This report describes a successful renal Tx in a patient with chronic renal failure, caused by dysplastic kidneys, who received a cadaveric kidney with post-infectious glomerulonephritis. Sequential renal biopsies were performed at 12 h before Tx, and at 1 h and on days 8 and 58 post-Tx. Post-operative hematuria disappeared on day 9 and proteinuria on day 13. Normal graft function was observed within 1 month, with histologic resolution. Our study suggests that while the donor kidney facilitates deposition of certain immune reactants, this is a host (environmental) problem and when transplanted into a new host (new environment), the problem is no longer sustained.
Mizuiri
S
S
Department of Nephrology, Toho University School of Medicine, Tokyo, Japan.
Shigetomi
Y
Y
Sugiyama
K
K
Miyagi
M
M
Hatano
T
T
Tajima
E
E
Aikawa
A
A
Ohara
T
T
Kawamura
S
S
Hasegawa
A
A
D000293:Adolescent; D002102:Cadaver; D002648:Child; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology / Q000473:pathology; D006801:Humans; D007239:Infections / Q000150:complications; D007668:Kidney / Q000473:pathology; D016030:Kidney Transplantation; D014019:Tissue Donors