title: Adherence of Bacteroides forsythus to host cells.
abstract: The adherence characteristics of Bacteroides forsythus to host cells, was examined. Four laboratory strains and twelve clinical isolates of B. forsythus were used. All strains demonstrated different haemagglutination activities. The haemagglutination of B. forsythus was inhibited strongly by amino acids such as L-arginine, L-histidine, L-lysine and L-alanine. The adherence to polymorphonuclear leucocytes (PMNL) was weak except for B. forsythus ATCC 43037 and OMZ 408. The adherence of these strains was inhibited by L-histidine and L-arginine, and was facilitated by trypsin (0.1 mg/ml) treatment of polymorphonucleocytes. B. forsythus strains showed varied adherence to fibroblasts. It is suggested that the adherence of B. forsythus to host cells is mediated by a factor which is sensitive against some amino acids, and altered by trypsin-like enzymes.
authors.affiliation: Department of Periodontology and Endodontology, Hiroshima University School of Dentistry, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Munemasa
authors.forename: T
authors.initials: T
authors.lastname: Takemoto
authors.forename: G
authors.initials: G
authors.lastname: Dahlén
authors.forename: T
authors.initials: T
authors.lastname: Hino
authors.forename: H
authors.initials: H
authors.lastname: Shiba
authors.forename: T
authors.initials: T
authors.lastname: Ogawa
authors.forename: H
authors.initials: H
authors.lastname: Kurihara
authors.forename: H
authors.initials: H
authors.lastname: Kurikara
mesh_terms: D000596:Amino Acids / Q000494:pharmacology; D001422:Bacterial Adhesion / Q000187:drug effects; D001439:Bacteroides / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D004912:Erythrocytes / Q000382:microbiology; D006384:Hemagglutination / Q000187:drug effects; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D009504:Neutrophils / Q000187:drug effects / Q000382:microbiology; D014357:Trypsin / Q000494:pharmacology
chemical_list: D000596:Amino Acids; D014357:Trypsin