title: Nucleic acids: theory and computer simulation, Y2K.
abstract: Molecular dynamics simulations on DNA and RNA that include solvent are now being performed under realistic environmental conditions of water activity and salt. Improvements to force-fields and treatments of long-range interactions have significantly increased the reliability of simulations. New studies of sequence effects, axis bending, solvation and conformational transitions have appeared.
authors.affiliation: Chemistry Department, Molecular Biophysics Program, Wesleyan University, Middletown, CT 06459, USA. dbeveridge@wesleyan.edu
authors.forename: D L
authors.initials: DL
authors.lastname: Beveridge
authors.forename: K J
authors.initials: KJ
authors.lastname: McConnell
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003198:Computer Simulation; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry; D007477:Ions; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D009843:Oligoribonucleotides / Q000737:chemistry; D012313:RNA / Q000737:chemistry; D012997:Solvents; D013816:Thermodynamics; D014867:Water
chemical_list: D007477:Ions; D009838:Oligodeoxyribonucleotides; D009843:Oligoribonucleotides; D012997:Solvents; D014867:Water; D012313:RNA; D004247:DNA