title: Acremonium keratitis in a patient with herpetic neurotrophic corneal disease.
abstract: Fungi belonging to the genus Acremonium Link ex Fries 1821 are ubiquitous environmental contaminants and soil saprophytes, but are infrequent pathogens in humans. These filamentous fungi (previously known as Cephalosporium) are an uncommon cause of mycotic keratitis. As in the case of other filamentous fungi, corneal trauma with contaminated matter is the most frequent risk factor for the infection. We report in this paper a case of keratomycosis caused by Acremoniumpotronii, in a patient with a history of herpetic keratitis. Medical treatment with amphotericin B was unsuccessful and the infection eventually resolved with penetrating keratoplasty.
authors.affiliation: Department of Ophthalmology, Hospital Xeral de Galicia, Spain. ingo@corevia.com
authors.forename: T
authors.initials: T
authors.lastname: Rodriguez-Ares
authors.forename: V
authors.initials: V
authors.lastname: De Rojas Silva
authors.forename: M P
authors.initials: MP
authors.lastname: Ferreiros
authors.forename: E P
authors.initials: EP
authors.lastname: Becerra
authors.forename: C C
authors.initials: CC
authors.lastname: Tome
authors.forename: M
authors.initials: M
authors.lastname: Sanchez-Salorio
mesh_terms: D000164:Acremonium / Q000302:isolation & purification*; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D000935:Antifungal Agents / Q000627:therapeutic use; D003319:Corneal Stroma / Q000382:microbiology; D003937:Diagnosis, Differential; D015821:Eye Infections, Fungal / Q000150:complications* / Q000382:microbiology / Q000628:therapy; D018259:Herpesvirus 1, Human / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D016849:Keratitis, Herpetic / Q000150:complications* / Q000382:microbiology* / Q000628:therapy; D015948:Keratoplasty, Penetrating; D008297:Male; D009181:Mycoses / Q000150:complications* / Q000382:microbiology / Q000628:therapy
chemical_list: D000914:Antibodies, Viral; D000935:Antifungal Agents