title: Cerebral blood flow in volunteers measured by PET and Xe CT/CBF. A comparison.
abstract: Aim of this study was to compare two quantitative CBF methods. Seven young, healthy volunteers were studied with PET (15-0 labelled water) and afterwards with Xe CT/CBF (30% xenon in oxygen, 3 minutes wash-in, 5 minutes washout protocol). Xe CT/CBF showed greater differences between high and low flow areas than PET CBF. Correlation was found within subjects between ROI's, but no agreement or correlation between the methods could be demonstrated. The disagreement in this study could be due to changes in PCO2.
authors.affiliation: Dept. of Neurosurgery, Aarhus University Hospital, Denmark.
authors.forename: B
authors.initials: B
authors.lastname: Bergholt
authors.forename: L
authors.initials: L
authors.lastname: Ostergaard
authors.forename: G
authors.initials: G
authors.lastname: von Oettingen
authors.forename: P
authors.initials: P
authors.lastname: Johannsen
authors.forename: P H
authors.initials: PH
authors.lastname: Poulsen
authors.forename: H
authors.initials: H
authors.lastname: Bundgaard
authors.forename: H
authors.initials: H
authors.lastname: Asboe
authors.forename: G E
authors.initials: GE
authors.lastname: Cold
authors.forename: A
authors.initials: A
authors.lastname: Gjedde
authors.forename: C
authors.initials: C
authors.lastname: Gyldensted
authors.forename: J
authors.initials: J
authors.lastname: Astrup
mesh_terms: D000328:Adult; D002560:Cerebrovascular Circulation; D006801:Humans; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed / Q000379:methods; D014978:Xenon
chemical_list: D014978:Xenon