title: A monthly period of symptoms associated with benign prostatic hyperplasia.
abstract: The number of times that a man with benign prostatic hyperplasia awoke each night with the urge to urinate (nocturia) was analyzed for randomness by Bartlett's Kolmogorov-Smirnov white noise test and for a periodic component by Fourier analysis. The data series (n = 1549) was not white noise; it had a peak periodic component of 25 days, with a range of 21 to 37 days. The possibility that the monthly period of nocturia is a general phenomenon and is coupled to a monthly menstrual period, and the implications for more accurate diagnosis and new modes of therapy, are discussed.
authors.affiliation: Department of Genetics and the Cancer Institute of New Jersey, Rutgers-The State University of New Jersey, Piscataway, New Jersey 08554-8082, USA.
authors.forename: D E
authors.initials: DE
authors.lastname: Axelrod
mesh_terms: D005583:Fourier Analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010507:Periodicity; D016012:Poisson Distribution; D011470:Prostatic Hyperplasia / Q000150:complications* / Q000175:diagnosis*; D014555:Urination Disorders / Q000209:etiology / Q000503:physiopathology*