title: Biliary migration of hepatocellular carcinoma fragment after transcatheter arterial chemoembolization therapy.
abstract: Occasional side-effects of transcatheter arterial chemoembolization therapy in hepatocellular carcinoma are essentially related to tissue necrosis. We report the case of a patient with hepatocellular carcinoma who experienced an acute common bile duct obstruction a few weeks after such a procedure, in the absence of obvious biliary tract invasion. An endoscopic sphincterotomy relieved the obstruction. At histology, the intra-biliary material was identified as a fragment of hepatocellular carcinoma. We discuss the causes of obstructive jaundice in the setting of hepatocellular carcinoma as well as in the specific situation of transcatheter arterial chemoembolization therapy.
authors.affiliation: Department of Gastroenterology and Hepatology, University Hospital, Geneva, Switzerland. laurent.spahr@hcuge.ch
authors.forename: L
authors.initials: L
authors.lastname: Spahr
authors.forename: J L
authors.initials: JL
authors.lastname: Frossard
authors.forename: C
authors.initials: C
authors.lastname: Felley
authors.forename: M A
authors.initials: MA
authors.lastname: Brundler
authors.forename: P E
authors.initials: PE
authors.lastname: Majno
authors.forename: A
authors.initials: A
authors.lastname: Hadengue
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000009:adverse effects*; D002780:Cholestasis, Intrahepatic / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male