title: Electroclinical correlation in neonatal seizures.
abstract: A dissociation between clinical and electroencephalographic phenomena is often observable in neonatal seizures. This finding raises important questions, including those related to the management of these patients. Another characteristic of neonatal convulsions is represented by their increased tendency towards status epilepticus. In order to examine the electroclinical correlation and its possible relationship to the occurrence of status epilepticus, recorded video-electroencephalograms of 17 newborns were submitted to detailed analysis. Time of onset, duration and other characteristics of all clinical and electrical events were noted. Five degrees of correlation were observed, from constant concurrence to complete dissociation. Examining the role of different parameters, it was observed that the incidence of electric discharges related significantly to the occurrence of electroclinical dissociation.
authors.affiliation: Stella Maris Scientific Institute and Institute of Developmental Neurology, Psychiatry and Educational Psychology, University of Pisa, Calambrone, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Biagioni
authors.forename: F
authors.initials: F
authors.lastname: Ferrari
authors.forename: A
authors.initials: A
authors.lastname: Boldrini
authors.forename: M F
authors.initials: MF
authors.lastname: Roversi
authors.forename: G
authors.initials: G
authors.lastname: Cioni
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D002391:Catchment Area, Health; D004569:Electroencephalography; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D015997:Neonatal Screening; D012189:Retrospective Studies; D012640:Seizures / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D012720:Severity of Illness Index; D014743:Videotape Recording
chemical_list: D000927:Anticonvulsants