[Effect of processing on toxcicity and analgesia of radix Aconiti coreani].
The experimental results showed that the Radix Aconiti Coreani and its processed products did not have remarkable toxic effect in p.o. But there was significant toxicity before processing and weakened toxicity after processing in i.p. In the skin test, the Radix Aconiti Coreani and its processed products showed no stimulating effect. The analgesic experiment showed that the Radix Aconiti Coreani and its steamed products could inhibit the pain. The products processed with bean curd and ginger-KAl(SO4)2.12H2O also could alleviate the pain induced by acetic acid, but no remarkable effect was observed in mice on the pain induced by hot plate.
Mao
S
S
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing.
Cheng
L
L
Wu
L
L
D000700:Analgesics / Q000627:therapeutic use*; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use* / Q000633:toxicity; D005260:Female; D006358:Hot Temperature; D007928:Lethal Dose 50; D019684:Magnoliopsida; D008297:Male; D051379:Mice; D010146:Pain / Q000188:drug therapy*; D010946:Plants, Medicinal; D013678:Technology, Pharmaceutical / Q000379:methods
D000700:Analgesics; D004365:Drugs, Chinese Herbal