[The corticosteroid therapy of premature rupture of the fetal membranes].
Antenatal corticosteroids are now administered for the purpose of hastening maturation of the preterm infant's organs and tissues, thus reducing neonatal mortality and the incidence of respiratory distress syndrome (RDS). Our purpose was to determine the efficacy of maternal corticosteroid therapy on fetal maturation in cases with preterm premature rupture of the membranes. The rates of RDS and survival in low birth weight infants treated with corticosteroids is influenced by the duration of the premature rupture of the membranes and the duration of the corticosteroid therapy, as well as by the gestational age.
Ruseva
R
R
Dimitrov
E
E
Slŭncheva
B
B
Iarŭkova
N
N
D000328:Adult; D001623:Betamethasone / Q000627:therapeutic use*; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000196:embryology / Q000517:prevention & control*; D005325:Fetal Organ Maturity / Q000187:drug effects; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008168:Lung / Q000196:embryology; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011295:Prenatal Care; D012189:Retrospective Studies
D005938:Glucocorticoids; D001623:Betamethasone