title: [Osteosarcoma manifesting as Paget's bone disease].
abstract: Osteosarcoma is a malignant bone tumour of mesenchymal osteoid tissue origin. Osteosarcoma can be primitive, but it may also complicated a Paget's disease of bone. We described a 75yearold man with a right thigh mass discovered after a motoring accident. Histopathologic examination revealed the diagnosis of osteosarcoma. Plain film Xrays showed Paget's lesion of the right pelvis bone. CT and MRI allowed complete evaluation of this lesion. Final diagnosis was those of malignant transformation of Paget disease. The patient was refused for surgery in view of the size of the tumour and chimiotherapy followed.
authors.affiliation: Service de radiologie générale, Institut Paoli Calmette, 250, boulevard SainteMarguerite, 13274 Marseille, France.
authors.forename: F
authors.initials: F
authors.lastname: Crozier
authors.forename: D
authors.initials: D
authors.lastname: Margain
authors.forename: B
authors.initials: B
authors.lastname: Lebrigand
authors.forename: F
authors.initials: F
authors.lastname: Lecrivain
authors.forename: F
authors.initials: F
authors.lastname: Ternier
authors.forename: R
authors.initials: R
authors.lastname: Rossello
authors.forename: D
authors.initials: D
authors.lastname: Di Stefano Louino
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010001:Osteitis Deformans / Q000150:complications*; D012516:Osteosarcoma / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D010384:Pelvic Bones; D011379:Prognosis; D014057:Tomography, X-Ray Computed