title: Diffuse annular fusiform adenocarcinoma in a dog.
abstract: Canine colonic intestinal adenocarcinoma typically presents as rectal polypoid or annular stenotic masses causing clinical signs consistent with large bowel disease. This report discusses an unusual case of intestinal adenocarcinoma in an 11-year-old, neutered male German shepherd dog presented for evaluation of anorexia, profuse watery diarrhea, and weight loss. In this dog, colonic adenocarcinoma diffusely infiltrated the entire large bowel and caused an annular fusiform lesion, as confirmed by endoscopic biopsies and postmortem examination. Other unique features included a paucity of desmoplasia associated with the neoplastic lesion and widespread metastasis to regional lymph nodes, lung, and prostate.
authors.affiliation: Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic and State University, Blacksburg 24061-0442, USA.
authors.forename: M R
authors.initials: MR
authors.lastname: Prater
authors.forename: B
authors.initials: B
authors.lastname: Flatland
authors.forename: S J
authors.initials: SJ
authors.lastname: Newman
authors.forename: D P
authors.initials: DP
authors.lastname: Sponenberg
authors.forename: J
authors.initials: J
authors.lastname: Chao
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D000818:Animals; D001005:Anus Neoplasms / Q000556:secondary / Q000662:veterinary*; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis*; D004285:Dogs; D008297:Male