title: Metabolic changes and urodynamic findings after continent urinary diversion.
abstract: Methods of creating continent urinary diversions were developed in the mid-1980s (neobladder, pouch) providing patients with continence and anatomically appropriate voluntary urine discharge. In a follow-up investigation on 18 patients, the question to be clarified was whether continent urinary diversion meets the demands of an ideal bladder substitute. Follow-up examination showed normal clinical test values almost without exception. Only five out of 18 patients had discrete acidosis. Neither malabsorption syndrome nor any disorder of vitamin D3 metabolism was found. Ultrasonography and X-ray diagnostics showed normal conditions, without stones and reflux. Urodynamic investigations revealed that bladder emptying was almost free of residual urine, and continence was largely undisturbed. In accordance with these data, there is almost perfect patient acceptance. At present, there are still no sufficient data on the risk of tumour induction, since the latency period required (about 20 years) in most cases has not yet been reached. Since there are currently numerous publications on "urinary diversion carcinoma", consistent follow-up is necessary comprising not only the metabolic, but also the oncological risks of urinary diversion via intestinal segments.
authors.affiliation: Department of Urology, Augsburg Central Hospital, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Weckermann
authors.forename: F
authors.initials: F
authors.lastname: Wawroschek
authors.forename: J
authors.initials: J
authors.lastname: Schipp
authors.forename: G
authors.initials: G
authors.lastname: Krawczak
authors.forename: R
authors.initials: R
authors.lastname: Harzmann
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014547:Urinary Diversion; D014549:Urinary Incontinence / Q000378:metabolism / Q000503:physiopathology* / Q000601:surgery*; D014563:Urodynamics