Uterine myxoid leiomyosarcoma within a leiomyoma.
A case of myxoid leiomyosarcoma of the uterus arising in a leiomyoma is reported. Although the tumor showed very low mitotic activity ranging from zero to 2/10 HPF, the presence of infiltrative pattern of growth and a high MIB-1 index (60% of cells positive) established the diagnosis. Myxoid leiomyosarcoma may arise in leiomyoma.
Mittal
K
K
New York University School of Medicine and Kaplan Cancer Center, New York, USA.
Popiolek
D
D
Demopoulos
R I
RI
D000368:Aged; D034961:Antigens, Nuclear; D002467:Cell Nucleus / Q000473:pathology; D005260:Female; D006801:Humans; D019394:Ki-67 Antigen; D007889:Leiomyoma / Q000378:metabolism / Q000473:pathology*; D007890:Leiomyosarcoma / Q000378:metabolism / Q000473:pathology*; D008940:Mitotic Index; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009687:Nuclear Proteins / Q000378:metabolism; D014594:Uterine Neoplasms / Q000378:metabolism / Q000473:pathology*
D034961:Antigens, Nuclear; D019394:Ki-67 Antigen; D009687:Nuclear Proteins