Trisomy 10 in acute myeloid leukemia: three new cases.
Trisomy 10 is a rare nonrandom cytogenetic abnormality found in association with acute myeloid leukemia (AML). The hematological and clinical features associated with this finding have not yet been clearly defined. A literature review revealed 13 cases of trisomy 10 in AML, some reported as a minority component of a more comprehensive AML study and therefore lacking a full description of both clinical and hematological features. We present a summary of these reports and add three new cases to the literature.
Llewellyn
I E
IE
Canterbury Health Laboratories, Christchurch, New Zealand.
Morris
C M
CM
Stanworth
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S
Heaton
D C
DC
Spearing
R L
RL
D000208:Acute Disease; D000328:Adult; D002879:Chromosomes, Human, Pair 10; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D014314:Trisomy