title: Susceptibility testing of Haemophilus influenzae to clarithromycin.
abstract: Susceptibility testing of Haemophilus influenzae to the macrolide compounds has often been problematic. This is as a result of the inability of many isolates of H. influenzae to grow without the addition of 5% CO2 to the incubation atmosphere and the subsequent detrimental effect that CO2 has on the activity of the macrolide group of compounds. This report describes refinements and recommendations for susceptibility testing of H. influenzae to the macrolide clarithromycin.
authors.affiliation: Department of Medical Microbiology, Edinburgh University Medical School, Teviot Place, Edinburgh EH8 9AG, UK. RHP@srv1.med.ed.ac.uk
authors.forename: R
authors.initials: R
authors.lastname: Paton
authors.forename: J
authors.initials: J
authors.lastname: Arnold
authors.forename: J
authors.initials: J
authors.lastname: Cockburn
authors.forename: F X
authors.initials: FX
authors.lastname: Emmanuel
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D017291:Clarithromycin / Q000494:pharmacology*; D006192:Haemophilus Infections / Q000382:microbiology; D006193:Haemophilus influenzae / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents; D017291:Clarithromycin