title: Syndromes of severe asthma.
abstract: Asthma responds to conventional therapy in the majority of patients. However, attention has recently focused on the 1 to 15% of asthmatics who are thought to manifest severe asthma, which responds poorly to commonly used regimens. In this review, current knowledge about the pathogenesis of severe asthma is reviewed and several distinct clinical syndromes of severe asthma are discussed.
authors.affiliation: James M. Collins Center for Biomedical Research, University of Texas Southwestern Medical Center at Dallas, Pulmonary and Critical Care Medicine, 75390-9034, USA. jweiss@mednet.swmed.edu
authors.forename: J C
authors.initials: JC
authors.lastname: Weissler
mesh_terms: D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D015267:Churg-Strauss Syndrome / Q000175:diagnosis / Q000628:therapy; D003937:Diagnosis, Differential; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D015994:Incidence; D010641:Phenotype; D011379:Prognosis; D012720:Severity of Illness Index; D013577:Syndrome
chemical_list: D018927:Anti-Asthmatic Agents; D005938:Glucocorticoids