Bacteroides fragilis enterotoxin gene sequences in patients with inflammatory bowel disease.
We identified enterotoxigenic Bacteroides fragilis in stool specimens of patients with inflammatory bowel disease and other gastrointestinal disorders. The organism was detected in 11 (13.2%) of 83 patients with inflammatory bowel disease. Of 57 patients with active disease, 19.3% were toxin positive; none of those with inactive disease had specimens positive for enterotoxigenic Bacteroides fragilis gene sequences.
Prindiville
T P
TP
University of California, Davis Medical Center, Sacramento, CA, USA.
Sheikh
R A
RA
Cohen
S H
SH
Tang
Y J
YJ
Cantrell
M C
MC
Silva
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001442:Bacteroides Infections / Q000209:etiology / Q000382:microbiology; D001441:Bacteroides fragilis / Q000235:genetics* / Q000472:pathogenicity*; D016022:Case-Control Studies; D002648:Child; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification; D004768:Enterotoxins / Q000235:genetics*; D005243:Feces / Q000382:microbiology; D005260:Female; D005798:Genes, Bacterial; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000209:etiology / Q000382:microbiology*; D008297:Male; D008666:Metalloendopeptidases / Q000235:genetics*; D008875:Middle Aged
D004269:DNA, Bacterial; D004768:Enterotoxins; D008666:Metalloendopeptidases; C091198:fragilysin