Hypocholesterolemic activity of Marsilea minuta in gerbils.
Feeding of a Marsilea minuta leaf extract [Fr. I] reduced serum cholesterol and triglycerides by 31 and 63%, respectively, in athero diet fed gerbils. Liver cholesterol and triglycerides were also lowered by 71 and 27%, respectively, in comparison to athero fed controls. Moreover, treatment with Fr. I prevented the accumulation of cholesterol and triglycerides in liver and aorta and was able to dissolve atheromatous plaques of thoracic and abdominal aorta. Fecal excretions of cholesterol and triglycerides were significantly increased in Fr. I fed gerbils.
Gupta
R S
RS
Department of Zoology, Reproductive Physiology Section, University of Rajasthan, Jaipur, India.
Kumar
P
P
Sharma
A
A
Bharadwaj
T N
TN
Dixit
V P
VP
D000818:Animals; D000924:Anticholesteremic Agents / Q000494:pharmacology*; D001011:Aorta / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D005849:Gerbillinae / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves; D010946:Plants, Medicinal; D014280:Triglycerides / Q000097:blood
D000924:Anticholesteremic Agents; D010936:Plant Extracts; D014280:Triglycerides; D002784:Cholesterol