title: Hepatitis B virus exposure in human immunodeficiency virus seropositive Cuban patients.
abstract: In order to estimate the prevalence of serological markers of exposure to Hepatitis B Virus (HBV), 295 subjects were selected at random from the National Registry of human immunodeficiency virus positive subjects. Evidence of exposure to HBV was defined as: testing Hepatitis B surface antigen (HBsAg) and anti-Hepatitis B core antigen (anti-HBc) positive or anti-HBc positive only. Overall, 133 (45.5%) were positive for anti-HBc and 15 (5.1%) resulted positive to HBsAg. Significant statistical association was found between male sex and exposure to HBV (p<0.01). Homosexual or bisexual behavior was found to be strongly associated to HBV exposure (p<0.001). In conclusion, the prevalence of HBV serological markers is higher in Cuban HIV positive subjects compared to the Cuban general population.
authors.affiliation: Laboratorio de Referencia para Hepatitis Virales, Departamento de Virología, Instituto Pedro Kourí, Habana, 601, Cuba. licel@ipk.sld.cu
authors.forename: L
authors.initials: L
authors.lastname: Rodríguez
authors.forename: F
authors.initials: F
authors.lastname: Collado-Mesa
authors.forename: U
authors.initials: U
authors.lastname: Aragón
authors.forename: B
authors.initials: B
authors.lastname: Díaz
authors.forename: J
authors.initials: J
authors.lastname: Rivero
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D003462:Cuba / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006679:HIV Seropositivity / Q000097:blood / Q000821:virology*; D006509:Hepatitis B / Q000097:blood* / Q000635:transmission / Q000821:virology*; D006512:Hepatitis B Core Antigens / Q000097:blood*; D006514:Hepatitis B Surface Antigens / Q000097:blood*; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D012725:Sexual Behavior
chemical_list: D015415:Biomarkers; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens