title: [Retrospective analysis of results of treatment of 91 oral cavity cancers from 1982 to 1992].
abstract: OBJECTIVE
  To analyse retrospectively the results of different treatment regimens of carcinomas of the floor of the mouth and tongue.
  
  
  METHODS
  Between 1982 and 1992, 61 patients with carcinoma of the floor of the mouth and 30 with tongue cancer (25 stage I, nine stage II, 28 stage III, 29 stage IV) were treated in the radiotherapy department of Poitiers. Nine patients with stage I tumours were treated with 70 Gy low-dose rate brachytherapy only, without nodal dissection. Stages II and III were treated with combined surgery with neck dissection; and radiotherapy of stage II with nodal metastasis and for all stage III cases. Stage IV cases were treated either surgically if possible, or with combined chemotherapy and radiation.
  
  
  RESULTS
  The five-year overall survival rate was 87.3% for stage I, 68.5% for stage II, 45.3% for stage III, and 0% for stage IV patients. Most relapses appeared in the first two years after treatment. Eight patients (32%) with stage I cancer developed nodal relapses, isolated in five cases. Complications of radiotherapy were acceptable. Four cases of osteonecrosis were observed after radiotherapy. All of these appeared simultaneously with a local relapse.
  
  
  CONCLUSIONS
  These results are comparable with reports in the literature. The remarkable observation of our study is the high incidence of nodal recurrences after local treatment of stage I tumours. Therefore, local treatment is insufficient for early-stage tumours. The question of neck dissection for the early stage is discussed.
authors.affiliation: Abteilung für Radioonkologie, Universität Göttingen, Allemagne.
authors.forename: O
authors.initials: O
authors.lastname: Pradier
authors.forename: E
authors.initials: E
authors.lastname: Hummers-Pradier
authors.forename: Z
authors.initials: Z
authors.lastname: Gaci
authors.forename: D
authors.initials: D
authors.lastname: Jadaud
authors.forename: J M
authors.initials: JM
authors.lastname: Descrozailles
authors.forename: P
authors.initials: P
authors.lastname: Gesta
authors.forename: T
authors.initials: T
authors.lastname: Germain
authors.forename: A
authors.initials: A
authors.lastname: Daban
authors.forename: C F
authors.initials: CF
authors.lastname: Hess
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001918:Brachytherapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D016019:Survival Analysis; D014062:Tongue Neoplasms / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D016896:Treatment Outcome