title: Videodensitometric quantitative angiography after coronary balloon angioplasty, compared to edge-detection quantitative angiography and intracoronary ultrasound imaging.
abstract: OBJECTIVE
  To assess the value of videodensitometric quantification of the coronary lumen after angioplasty by comparison to two other techniques of coronary artery lumen quantification.
  
  
  RESULTS
  Videodensitometric quantitative angiography, edge detection quantitative angiography and 30 MHz intracoronary ultrasound imaging were performed after successful balloon angioplasty in 161 patients. Lumen cross-sectional areas were mean (SD) 2.82 (1.15) mm(2)for edge detection quantitative angiography, 3.67 (1.5) mm(2)for videodensitometric quantitative angiography and 5.32 (1.75) mm(2)for intracoronary ultrasound imaging (P<0.001). The correlation between intracoronary ultrasound imaging and videodensitometric quantitative angiography (r=0.44) was almost similar to that of intracoronary ultrasound imaging and edge detection quantitative angiography (r=0. 47). The correlation between the three techniques was not significantly influenced by the presence of ruptures and dissections on intracoronary ultrasound imaging. The absence of calcifications improved the correlation between videodensitometry and intracoronary ultrasound imaging.
  
  
  CONCLUSIONS
  The luminal dimensions as measured by videodensitometric quantitative angiography matched intracoronary ultrasound imaging derived dimensions more closely than edge detection quantitative angiography. Videodensitometric quantitative angiography represents an on-line alternative to intracoronary ultrasound imaging for quantitative analysis regardless of the degree of vessel damage.
authors.affiliation: Academic Medical Center, Department of Cardiology, Amsterdam, The Netherlands. The PICTURE Study Group.
authors.forename: R J
authors.initials: RJ
authors.lastname: Peters
authors.forename: W E
authors.initials: WE
authors.lastname: Kok
authors.forename: G
authors.initials: G
authors.lastname: Pasterkamp
authors.forename: C
authors.initials: C
authors.lastname: Von Birgelen
authors.forename: M
authors.initials: M
authors.lastname: Prins
authors.forename: P W
authors.initials: PW
authors.lastname: Serruys
mesh_terms: D015502:Absorptiometry, Photon; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography / Q000379:methods; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000628:therapy; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D018084:Ultrasonography, Interventional