title: [Self-organization of mitochondrial associates and effects of negative air ions].
abstract: A convenient model for studying the mechanisms of biological self-organization is described by morphometric investigation of formation of mitochondrion associations in medium containing physiological concentration of potassium ions without nonpolar substances. Association formation was considerably better at 15-18 degrees C during isolation and storage than at 0 degree C. The existence of filamented mitochondria in homogenate was also shown by staining of succinate dehydrogenase. Formation of associations increased in medium pretreated with negative air ions carrying superoxide and is probably due to hydrogen peroxide. The effect of substances influencing the surface charge on association formation was studied.
authors.affiliation: Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Temnov
authors.forename: T V
authors.initials: TV
authors.lastname: Sirota
authors.forename: I G
authors.initials: IG
authors.lastname: Stavrovskaia
authors.forename: M N
authors.initials: MN
authors.lastname: Kondrashova
mesh_terms: D000388:Air; D000818:Animals; D066298:In Vitro Techniques; D007477:Ions; D008297:Male; D008930:Mitochondria, Liver / Q000201:enzymology / Q000648:ultrastructure*; D011188:Potassium; D051381:Rats; D017208:Rats, Wistar; D013385:Succinate Dehydrogenase / Q000378:metabolism; D013481:Superoxides; D013696:Temperature
chemical_list: D007477:Ions; D013481:Superoxides; D013385:Succinate Dehydrogenase; D011188:Potassium