title: Transformation of mitral valve prolapse to dynamic left ventricular outflow tract obstruction and back again in a patient with acute transient myocardial depression.
abstract: We describe an unusual case of transient resolution of preexisting mitral valve (MV) prolapse during acute cardiac dysfunction and the development of dynamic left ventricular (LV) outflow tract obstruction. The patient presented with lightheadedness, chest pain, and compromised hemodynamic status. Echocardiography revealed akinesis and deformation of the LV anterior wall and apex, hyperdynamic activity in the bases, anterior MV leaflet systolic anterior motion without prolapse, and a dynamic outflow tract gradient. Myocardial function fully recovered over 1 month. Repeat ultrasonography showed posterior MV leaflet prolapse and no anterior MV leaflet systolic anterior motion. Elongated MV leaflets may have contributed to dynamic outflow tract obstruction and life-threatening hemodynamic compromise during LV conformational change.
authors.affiliation: University of Rochester, Cardiology Unit, NY 14642, USA.
authors.forename: S D
authors.initials: SD
authors.lastname: Fisher
authors.forename: J P
authors.initials: JP
authors.lastname: Eichelberger
authors.forename: R
authors.initials: R
authors.lastname: Pomerantz
authors.forename: J
authors.initials: J
authors.lastname: Delehanty
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D008945:Mitral Valve Prolapse / Q000150:complications*; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000209:etiology; D014694:Ventricular Outflow Obstruction / Q000000981:diagnostic imaging* / Q000209:etiology*