title: Testing for glaucoma with the spatial frequency doubling illusion.
abstract: We examined the performance of tests for glaucoma based on the spatial frequency doubling (FD) illusion. Contrast thresholds for seeing the FD illusion in four large visual field regions were measured from 340 subjects who were tested up to seven times over 2 years. Median sensitivities of 91% at specificities of 95% were obtained. Test-retest variability for the worst hemifield thresholds averaged 2.22 db +/- 0.09 S.E. for all tested groups, and significant progression was observed for glaucoma suspects over the seven visits, indicating that tests based on the FD illusion can detect diffuse early glaucomatous loss.
authors.affiliation: Centre for Visual Sciences, Research School of Biological Science, Australian National University, Canberra, ACT, Australia. ted.maddess@anu.edu.au
authors.forename: T
authors.initials: T
authors.lastname: Maddess
authors.forename: I
authors.initials: I
authors.lastname: Goldberg
authors.forename: J
authors.initials: J
authors.lastname: Dobinson
authors.forename: S
authors.initials: S
authors.lastname: Wine
authors.forename: A H
authors.initials: AH
authors.lastname: Welsh
authors.forename: A C
authors.initials: AC
authors.lastname: James
mesh_terms: D000328:Adult; D000368:Aged; D015350:Contrast Sensitivity; D018450:Disease Progression; D005500:Follow-Up Studies; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D008875:Middle Aged; D009903:Optical Illusions; D010775:Photic Stimulation / Q000379:methods; D012372:ROC Curve; D012680:Sensitivity and Specificity; D014787:Vision Tests / Q000379:methods*