Nonsmall cell lung adenocarcinoma metastatic to the vitreous without fundus lesions.
A 76-year-old man presented with vitritis in the absence of visible fundus lesions. Vitreal cytologic analysis revealed adenocarcinoma; immunostaining was consistent with a pulmonary origin. This case highlights the need to exclude metastasis to the vitreous in a patient with an oncologic history, even in the absence of visible posterior segment lesions. It also illustrates the utility of immunostaining to better determine the tissue of origin when a metastatic lesion is encountered.
Latkany
P
P
Department of Ophthalmology, Indiana University School of Medicine, Indianapolis 46204, USA.
Ciulla
T A
TA
Younger
C
C
Gao
H
H
D000230:Adenocarcinoma / Q000556:secondary*; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000556:secondary*; D003937:Diagnosis, Differential; D005134:Eye Neoplasms / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D014822:Vitreous Body / Q000473:pathology