title: Non-specific granulomatous inflammatory lesions of small bowel.
abstract: The entity of nonspecific granulomatous inflammatory lesions(NSGIL) of the small bowel is a diagnostic and therapeutic dilemma. Data of 52 histopathologically proven cases of NSGIL seen by us between 1986 and 1991 were analysed. All these patients presented with either intestinal obstruction or perforation. They were thoroughly evaluated and investigated for tuberculosis. Of the 52 patients, 6 patients received antitubercular therapy (ATT) before and after surgery and 32 patients only after surgery. Fourteen patients did not receive ATT. Surgical procedures undertaken included stricturoplasty, resection/anastomosis and simple suturing of perforation. No complications were seen in patients who received ATT; however, six of 14 patients who did not receive ATT developed wound sepsis and 2 developed partial wound dehiscence. Many of these NSGIL lesions could be tuberculous in etiology though typical caseating granulomas were not seen.
authors.affiliation: Dept of Surgery, Seth GS Medical College, Bombay.
authors.forename: R D
authors.initials: RD
authors.lastname: Bapat
authors.forename: D K
authors.initials: DK
authors.lastname: Ravishankar
authors.forename: O
authors.initials: O
authors.lastname: Rohandia
authors.forename: A S
authors.initials: AS
authors.lastname: Joshi
authors.forename: I M
authors.initials: IM
authors.lastname: Vora
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000008:administration & dosage; D001500:BCG Vaccine / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D005260:Female; D006099:Granuloma / Q000150:complications* / Q000473:pathology; D006801:Humans; D007410:Intestinal Diseases / Q000150:complications* / Q000473:pathology; D007415:Intestinal Obstruction / Q000209:etiology* / Q000601:surgery; D007416:Intestinal Perforation / Q000209:etiology* / Q000601:surgery; D007421:Intestine, Small; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014385:Tuberculosis, Gastrointestinal / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents; D001500:BCG Vaccine