title: [Isolation of highly active strain producing the antistaphylococcal antibiotic batumin].
abstract: The use of chemical and UV-induced mutageneses allowed us to increase the biosynthetic activity of the strain capable of producing new antistaphylococcal antibiotic, batumin. The strain of Pseudomonas batumici N17 producing 87-100 mg batumin per liter culture liquid was selected. Its activity was 3.5-5 times higher than the activity of the most potent natural strain. P. batumici N17 was shown to be stable in relation to the synthesis of batumin.
authors.affiliation: Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Kiev, Ukraine.
authors.forename: V V
authors.initials: VV
authors.lastname: Smirnov
authors.forename: L N
authors.initials: LN
authors.lastname: Churkina
authors.forename: V I
authors.initials: VI
authors.lastname: Perepnikhatka
authors.forename: N S
authors.initials: NS
authors.lastname: Mukvich
authors.forename: A D
authors.initials: AD
authors.lastname: Garagulia
authors.forename: E A
authors.initials: EA
authors.lastname: Kiprianova
authors.forename: A N
authors.initials: AN
authors.lastname: Kravets
authors.forename: S A
authors.initials: SA
authors.lastname: Dovzhenko
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000494:pharmacology; D016296:Mutagenesis; D009930:Organic Chemicals; D011549:Pseudomonas / Q000235:genetics / Q000378:metabolism* / Q000528:radiation effects; D013210:Staphylococcus / Q000187:drug effects*; D014466:Ultraviolet Rays
chemical_list: D000900:Anti-Bacterial Agents; D009930:Organic Chemicals; C088306:batumin