Proliferation of periodontal squamous epithelium in mink fed 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
The maxilla and mandible from 2 adult female mink fed 5.0 ppb 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for 6 mo were grossly unremarkable, but histologically had nests of squamous epithelium within the periodontal ligament. There was osteolysis of the adjacent alveolar bone.
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J A
JA
Department of Veterinary Pathology, Michigan State University, East Lansing, USA.
Hochstein
J R
JR
Aulerich
R J
RJ
Bursian
S J
SJ
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D004785:Environmental Pollutants / Q000633:toxicity*; D004847:Epithelial Cells / Q000187:drug effects* / Q000473:pathology; D005260:Female; D008334:Mandible / Q000187:drug effects / Q000473:pathology; D008437:Maxilla / Q000187:drug effects / Q000473:pathology; D008907:Mink; D010014:Osteolysis / Q000139:chemically induced / Q000473:pathology; D010513:Periodontal Ligament / Q000187:drug effects* / Q000473:pathology; D000072317:Polychlorinated Dibenzodioxins / Q000633:toxicity*
D004785:Environmental Pollutants; D000072317:Polychlorinated Dibenzodioxins