title: Influence of the maze procedure on the treatment of rheumatic atrial fibrillation - evaluation of rhythm control and clinical outcome in a comparative study.
abstract: OBJECTIVE
  The aim of this study was to evaluate the influence of the maze procedure on the treatment of rheumatic atrial fibrillation in patients with mitral valve disease.
  
  
  METHODS
  Fifty-five patients (mean age 51 years; 47 females) with rheumatic mitral valve disease and associated atrial fibrillation in New York Heart Association functional class III or IV, preoperatively, were operated upon. Thirty-five had double dysfunction, 19 had stenosis, and one had mitral regurgitation. None had other associated heart diseases or previous operations. The patients were divided into two groups: GI, 20 patients were treated for mitral valve disease with associated maze procedure; GII, 35 patients were treated for mitral valve disease without the maze procedure. The preoperative echocardiogram showed a left atrial diameter in GI of 5.35 mm and in GII of 5.57 mm (P=0.779). The groups were considered clinically similar (P=0.759). Cardiopulmonary bypass was used in all patients. The mitral valve was replaced with a biological prosthesis in 24 patients and repaired in 31 patients.
  
  
  RESULTS
  Three hospital deaths occurred, one in GI, two in GII. After cardiopulmonary bypass, 37.1% of patients in GII remained in atrial fibrillation. All patients in GI recovered regular rhythm (P<0.0001). In the ICU, atrial fibrillation was detected in 80% of patients in GII and maintained in 76.4% in a mean follow-up period of 38.5 months. In GI, atrial fibrillation occurred in 20% of patients in the ICU and maintained in 5.3% in 41 months of mean follow-up (P=0.0001). None of the patients in GI and 20.6% of patients in GII had a thromboembolic episode 1-63 months after the operation (P=0.041). Four late deaths occurred (two in each group), two being due to progression of valvular disease, one after an episode of pulmonary infection and one with no cardiac cause.
  
  
  CONCLUSIONS
  The maze procedure is effective in treating atrial fibrillation in patients with rheumatic mitral valve disease. The results are sustained in the mid-term follow-up period, preventing postoperative thromboembolic episodes, and with acceptable morbidity and mortality.
authors.affiliation: InCor-Heart Institute, University of São Paulo Medical School, São Paulo, Brazil. mjatene@sherwod.com.br
authors.forename: M B
authors.initials: MB
authors.lastname: Jatene
authors.forename: M B
authors.initials: MB
authors.lastname: Marcial
authors.forename: F
authors.initials: F
authors.lastname: Tarasoutchi
authors.forename: R A
authors.initials: RA
authors.lastname: Cardoso
authors.forename: P
authors.initials: P
authors.lastname: Pomerantzeff
authors.forename: A D
authors.initials: AD
authors.lastname: Jatene
mesh_terms: D001281:Atrial Fibrillation / Q000601:surgery*; D001705:Bioprosthesis; D002315:Cardiopulmonary Bypass; D016022:Case-Control Studies; D005260:Female; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology; D012214:Rheumatic Heart Disease / Q000601:surgery*; D013997:Time Factors