title: Novel catalytic asymmetric sulfoxidation in water using the hypervalent iodine reagent iodoxybenzene.
abstract: A new catalytic asymmetric oxidation of sulfides to sulfoxides in water using the hypervalent iodine(V) reagent iodoxybenzene (PhIO2) has been developed. This methodology is distinctly different from the previously reported use of cyclodextrins or biological catalysts and provides a new route to asymmetric sulfoxidation in water.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Tohma
authors.forename: S
authors.initials: S
authors.lastname: Takizawa
authors.forename: H
authors.initials: H
authors.lastname: Morioka
authors.forename: T
authors.initials: T
authors.lastname: Maegawa
authors.forename: Y
authors.initials: Y
authors.lastname: Kita
mesh_terms: D002384:Catalysis; D007202:Indicators and Reagents; D007462:Iodobenzenes / Q000737:chemistry*; D010084:Oxidation-Reduction; D013454:Sulfoxides / Q000138:chemical synthesis*; D014867:Water
chemical_list: D007202:Indicators and Reagents; D007462:Iodobenzenes; D013454:Sulfoxides; D014867:Water; C057598:iodoxybenzene