The expression pattern of a novel Deltex homologue during chicken embryogenesis.
We isolated a partial cDNA encoding a novel chicken homologue of human Deltex (DTX1), a member of the Notch signaling pathway. The cDtx2 sequence showed higher homology to KIAA0937 protein (92% identical) than to DTX1 (68% identical). cDtx2 is expressed widely in the epiblast at stage 4. Later in development it is expressed in many neural and sensory structures, such as neural tube, migrating neural crest cells, epidermal placodes, cranial ganglia, and the optic and otic vesicles.
Frolova
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Department of Ophthalmology and Visual Science, Washington University, St. Louis, MO 63110, USA. frolova@am.seer.wustl.edu
Beebe
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D000595:Amino Acid Sequence; D000818:Animals; D001921:Brain / Q000196:embryology / Q000502:physiology; D002352:Carrier Proteins; D002642:Chick Embryo; D029721:Drosophila Proteins; D004817:Epidermis / Q000196:embryology / Q000502:physiology; D005123:Eye / Q000196:embryology / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D019476:Insect Proteins / Q000235:genetics* / Q000378:metabolism; D008565:Membrane Proteins; D008969:Molecular Sequence Data; D009432:Neural Crest / Q000196:embryology / Q000502:physiology; D011506:Proteins / Q000235:genetics* / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D013116:Spinal Cord / Q000196:embryology / Q000502:physiology
D002352:Carrier Proteins; C086679:DX protein, Drosophila; D029721:Drosophila Proteins; D019476:Insect Proteins; D008565:Membrane Proteins; D011506:Proteins; C409218:deltex protein, vertebrate