title: Glucose-6-phosphate dehydrogenase deficiency in northern Vietnam.
abstract: Glucose-6-phosphate dehydrogenase (G6PD) deficiency was evaluated in 1676 schoolboys in northern Vietnam. The trait was nearly absent in boys of the Kinh (0.5%) and the Mong (0.7%) ethnic groups that traditionally have lived outside malaria transmission areas. Prevalences among ethnic groups living in the foothills, the breeding area of the main malaria vector Anopheles minimus, ranged from 9.7% to 31%. These findings support the hypothesis of a selective advantage of the trait in Plasmodium falciparum-endemic areas.
authors.affiliation: Belgian Administration for Development Cooperation, Brussels, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Verlé
authors.forename: D H
authors.initials: DH
authors.lastname: Nhan
authors.forename: T T
authors.initials: TT
authors.lastname: Tinh
authors.forename: T T
authors.initials: TT
authors.lastname: Uyen
authors.forename: N D
authors.initials: ND
authors.lastname: Thuong
authors.forename: A
authors.initials: A
authors.lastname: Kongs
authors.forename: P
authors.initials: P
authors.lastname: Stuyft
authors.forename: M
authors.initials: M
authors.lastname: Coosemans
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D019353:Endemic Diseases; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000453:epidemiology* / Q000208:ethnology; D006801:Humans; D016778:Malaria, Falciparum / Q000453:epidemiology*; D008297:Male; D015995:Prevalence; D014744:Vietnam / Q000453:epidemiology