title: RNA on the road to myelin.
abstract: In oligodendrocytes some mRNAs are transported from the perikaryon to the distal processes and localized in the myelin compartment where they are translated. This review describes the cis-acting signals and trans-acting factors that mediate intracellular trafficking of myelin basic protein (MBP) RNA, the prototype for such mRNAs in myelinating glia.
authors.affiliation: Departments of Neurology, Graduate Programs, University of Connecticut Health Center, Farmington, CT, USA.
authors.forename: E
authors.initials: E
authors.lastname: Barbarese
authors.forename: C
authors.initials: C
authors.lastname: Brumwell
authors.forename: S
authors.initials: S
authors.lastname: Kwon
authors.forename: H
authors.initials: H
authors.lastname: Cui
authors.forename: J H
authors.initials: JH
authors.lastname: Carson
mesh_terms: D000818:Animals; D001692:Biological Transport / Q000502:physiology; D006801:Humans; D009186:Myelin Sheath / Q000378:metabolism*; D009836:Oligodendroglia / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism*
chemical_list: D012333:RNA, Messenger