title: [Age characteristics of K(+) transport in the rat distal colon].
abstract: In vitro and in vivo experiments with perfusion in 20- and 60-day old rats revealed that K+ absorption in the gut as well as 86Rb uptake in the distal colon was significantly higher in younger rats due probable, to the higher activity of the apex-located K+-dependent ATPase and lower activity of the basolateral K+-carriers. The luminal blockade of K+ absorbing pumps with ouabain or omeprazole resulted in a decrease of the K+ absorption and K2 accumulation in skeletal muscles. The higher K+-absorbing/K_ secreting mechanisms ratio in younger rats contributes to the positive potassium balance.
authors.affiliation: Novosibirsk State Pedagogical University, Novosibirsk, 630126, Viluiskaya St., 28, Russia.
authors.forename: R I
authors.initials: RI
authors.lastname: Aĭzman
authors.forename: E N
authors.initials: EN
authors.lastname: Borovets
authors.forename: A D
authors.initials: AD
authors.lastname: Gerasev
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000375:Aging / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport; D002352:Carrier Proteins / Q000378:metabolism; D002712:Chlorides / Q000378:metabolism; D003106:Colon / Q000201:enzymology / Q000378:metabolism*; D017506:H(+)-K(+)-Exchanging ATPase / Q000378:metabolism; D007408:Intestinal Absorption; D011188:Potassium / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012964:Sodium / Q000378:metabolism; D028021:Sodium-Potassium-Chloride Symporters; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D002712:Chlorides; D028021:Sodium-Potassium-Chloride Symporters; D012964:Sodium; D000251:Adenosine Triphosphatases; D017506:H(+)-K(+)-Exchanging ATPase; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium