title: Mortality and repeat interventions up until 20 years after aorto-coronary bypass surgery with saphenous vein grafts. A follow-up study of 1041 patients.
abstract: OBJECTIVE
  To determine very long-term survival and incidence of recurrent interventions following aorto-coronary bypass surgery using venous grafts.
  
  
  RESULTS
  A group of 1041 consecutive patients operated upon between 1971 and 1980 were followed for a median of 19 years (range 13-26). Peri-operative mortality was 1.2%. Survival probability at 5, 10, 15, and 20 years was 92%, 77%, 57%, and 40%, respectively. After 5 or more years following operation the mortality was higher than in the matched Dutch population. Age, extent of coronary artery disease, and ejection fraction are independent predictors of mortality. Of the 593 deceased patients at least 63% died of a probable cardiac cause, while cardiovascular mortality is 40% in the general Dutch population. Repeat revascularization procedures (aorto-coronary bypass surgery or percutaneous transluminal coronary angioplasty) were performed in 343 patients (33%), with an increasing incidence after 7 years.
  
  
  CONCLUSIONS
  Aorto-coronary bypass surgery using vein grafts is safe and has a reasonable long-term prognosis for survival, although less than a matched population. After approximately 7 years both mortality and the need for repeated revascularizations increased. Since a majority of patients died of a cardiac cause and a substantial number of patients required repeated revascularization, aorto-coronary bypass surgery is a palliative treatment of a progressive disease.
authors.affiliation: Division of Cardiology, Thorax Center of the Academic Hospital Rotterdam "Dijkzigt", Rotterdam, The Netherlands.
authors.forename: R F
authors.initials: RF
authors.lastname: Veldkamp
authors.forename: S D
authors.initials: SD
authors.lastname: Valk
authors.forename: R T
authors.initials: RT
authors.lastname: van Domburg
authors.forename: L A
authors.initials: LA
authors.lastname: van Herwerden
authors.forename: K
authors.initials: K
authors.lastname: Meeter
mesh_terms: D006328:Cardiac Catheterization; D001026:Coronary Artery Bypass / Q000379:methods* / Q000401:mortality*; D003327:Coronary Disease / Q000401:mortality* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D011379:Prognosis; D012086:Reoperation; D012501:Saphenous Vein / Q000637:transplantation*; D016019:Survival Analysis; D013997:Time Factors