title: Worse six-month outcome for patients with multiple stents in a single coronary artery.
abstract: BACKGROUND
  Before the "era" of optimal stent deployment, very few data concerning multiple stents in a single coronary artery showed restenosis rates up to 60%.
  
  
  OBJECTIVE
  To evaluate the 6-month outcome of patients receiving multiple Palmaz-Schatz stents (> or =2 stents) in a single coronary artery compared to those receiving single stents.
  
  
  METHODS
  Three hundred and forty-eight patients having multiple stents were compared to 174 patients receiving single stents during a 6-month follow-up.
  
  
  RESULTS
  Repeat target lesion revascularization (RTLR), either repeat PTCA or CABG, was 10.4% in the single-stent group, 22.6% in the two-stent group, and 23.1% in the > or =2 stent group (p = 0.001, single versus 2 or > or =2 stents). There was not a significant difference between single stent and multiple stent groups in myocardial infarction and death during 6-month follow-up. Multivariate analysis showed multiple stents, diabetes mellitus, and type C lesion to be predictors of RTLR.
  
  
  CONCLUSIONS
  Placement of two or more stents was associated with a significantly higher RTLR compared with single stent placement. The optimal approach to diffuse coronary artery disease remains to be defined.
authors.affiliation: Watson Clinic LLP, Lakeland, Florida.
authors.forename: E
authors.initials: E
authors.lastname: Gaxiola
authors.forename: R E
authors.initials: RE
authors.lastname: Vlietstra
authors.forename: K F
authors.initials: KF
authors.lastname: Browne
authors.forename: D G
authors.initials: DG
authors.lastname: Ebersole
authors.forename: A S
authors.initials: AS
authors.lastname: Brenner
authors.forename: T T
authors.initials: TT
authors.lastname: Weeks
authors.forename: M H
authors.initials: MH
authors.lastname: Mines
authors.forename: L
authors.initials: L
authors.lastname: Roman
authors.forename: R A
authors.initials: RA
authors.lastname: Kerensky
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects* / Q000401:mortality; D001026:Coronary Artery Bypass; D023903:Coronary Restenosis / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology / Q000628:therapy; D012086:Reoperation; D015607:Stents / Q000009:adverse effects*; D013997:Time Factors; D016896:Treatment Outcome