Risk factors for lacunar stroke: a case-control transesophageal echocardiographic study.
To reassess the independent risk factors for lacunar stroke and to clarify the role of potential embolic sources, we conducted a case-control study using transesophageal echocardiography and duplex ultrasonography. Among 62 consecutive patients with their first lacunar stroke and 202 normal controls, we found that hypertension (p < 0.001), smoking (p = 0.001), and aortic arch atheroma (p = 0.006) were independently associated with an increased risk of lacunar stroke. Whether proximal aortic arch atheroma is mechanistically associated with lacunar stroke or merely coexistent is uncertain.
Kazui
S
S
National Stroke Research Institute, Austin & Repatriation Medical Centre, Victoria, Australia.
Levi
C R
CR
Jones
E F
EF
Quang
L
L
Calafiore
P
P
Donnan
G A
GA
D000368:Aged; D016022:Case-Control Studies; D017548:Echocardiography, Transesophageal; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D020521:Stroke / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed