title: PII signal transduction proteins.
abstract: PII proteins, found in Bacteria, Archaea and plants, help coordinate carbon and nitrogen assimilation by regulating the activity of signal transduction enzymes in response to diverse signals. Recent studies of bacterial PII proteins have revealed a solution to the signal transduction problem of how to coordinate multiple receptors in response to diverse stimuli yet permit selective control of these receptors under various conditions and allow adaptation of the system as a whole to long-term stimulation.
authors.affiliation: Dept of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109-0606, USA. aninfa@umich.edu
authors.forename: A J
authors.initials: AJ
authors.lastname: Ninfa
authors.forename: M R
authors.initials: MR
authors.lastname: Atkinson
mesh_terms: D000595:Amino Acid Sequence; D001419:Bacteria / Q000378:metabolism; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism*; D002244:Carbon / Q000378:metabolism; D002352:Carrier Proteins / Q000737:chemistry / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism*; D005057:Eukaryotic Cells / Q000378:metabolism; D008958:Models, Molecular; D009584:Nitrogen / Q000378:metabolism; D051922:PII Nitrogen Regulatory Proteins; D015398:Signal Transduction; D013329:Structure-Activity Relationship
chemical_list: D001426:Bacterial Proteins; D002352:Carrier Proteins; C113488:GlnK protein, Azorhizobium caulinodans; D051922:PII Nitrogen Regulatory Proteins; C404143:PIID regulatory protein, Bacteria; D002244:Carbon; D009584:Nitrogen