Infectious agents in bovine embryo production: hazards and solutions.
Infectious agents in systems for producing bovine embryos might reduce the number and quality of embryos generated, result in transmission of disease to recipients and offspring, or confound findings of research. Embryo-associated pathogens might also jeopardize human health when the goal of embryo production is creating transgenic animals intended to be a source of pharmaceuticals or organs. This paper addresses risks and resulting hazards of pathogen and microbial contaminant introduction into in vivo or in vitro embryo production systems. Additionally, methods for prevention and quality control are discussed.
Stringfellow
D A
DA
College of Veterinary Medicine, Auburn University, Alabama 36849-5519, USA.
Givens
M D
MD
D000818:Animals; D002417:Cattle / Q000196:embryology*; D002418:Cattle Diseases / Q000382:microbiology*; D046508:Culture Techniques; D004624:Embryo Transfer / Q000662:veterinary; D004622:Embryo, Mammalian / Q000382:microbiology*; D005307:Fertilization in Vitro / Q000662:veterinary; D007239:Infections / Q000635:transmission / Q000662:veterinary*