title: Gastroesophageal reflux in Pierre Robin sequence--early surgical treatment.
abstract: OBJECTIVE
  To assess the prevalence of gastroesophageal reflux (GER) in patients with Pierre Robin sequence and to assess whether early palatoplasty with subperiosteal release of the floor of the mouth eliminates upper respiratory tract infections and gastroesophageal reflux.
  
  
  METHODS
  In the period from 1993 to 1997, 24 children with Pierre Robin sequence were treated. Because GER is known to occur in patients with this syndrome, we screened for GER in each child for whom an early palatoplasty was to be performed at 3 months of age. In 21 cases, the presence of GER was confirmed. Within the past 2 years, palatoplasty has been combined with subperiosteal release of the floor of the mouth (SRFM). Prompt clinical improvement and shortened hospital stays have resulted.
  
  
  CONCLUSIONS
  Follow-up studies performed several months after the surgery showed no evidence of GER. The authors conclude that an early closure of the impaired palatopharyngeal ring and the elimination of the mechanism that causes the posterior rotation of the tongue can reduce the need for such surgical procedures as glossopexy, gastrostomy, tracheostomy, and Nissen's fundoplication.
authors.affiliation: Department of Pediatric Surgery and Centre for Craniofacial Disorders, National Research Institute for Mother and Child, Warsaw, Poland. Zofia.Dudkiewicz@imid.med.pl
authors.forename: Z
authors.initials: Z
authors.lastname: Dudkiewicz
authors.forename: E
authors.initials: E
authors.lastname: Sekuła
authors.forename: A
authors.initials: A
authors.lastname: Nielepiec-Jałosińska
mesh_terms: D002675:Child, Preschool; D005260:Female; D005764:Gastroesophageal Reflux / Q000209:etiology* / Q000517:prevention & control*; D006801:Humans; D007223:Infant; D008297:Male; D009060:Mouth Floor / Q000601:surgery; D010156:Palatal Muscles / Q000601:surgery; D010159:Palate / Q000601:surgery; D010855:Pierre Robin Syndrome / Q000150:complications* / Q000601:surgery; D012141:Respiratory Tract Infections / Q000209:etiology / Q000517:prevention & control