Gonadal cryopreservation in the young patient with gynaecological malignancy.
For patients who are planning to have chemotherapy, radiotherapy or to undergo bilateral oophorectomy, the loss of ovarian function will result in premature ovarian menopause and loss of fertility. Embryo preservation is not an option for single women or married women because delaying treatment for at least 2 months of in-vitro fertilization cycles is inappropriate and may be life-threatening. This study reports on the indications for ovarian tissue cryobanking and the state of the art of this method in preserving fertility in women with iatrogenic premature menopause.
Donnez
J
J
Department of Gynaecology, Catholic University of Louvain, Cliniques Universitaires St. Luc, Brussels, Belgium.
Godin
P A
PA
Qu
J
J
Nisolle
M
M
D000818:Animals; D015925:Cryopreservation; D046508:Culture Techniques; D005260:Female; D005833:Genital Neoplasms, Female / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D009865:Oocytes / Q000502:physiology; D006080:Ovarian Follicle / Q000502:physiology; D010053:Ovary / Q000637:transplantation