title: Successful palliation of hypoactive delirium due to multi-organ failure by oral methylphenidate.
abstract: Delirium is frequently observed in terminally ill cancer patients, but complete remission is often difficult to achieve. Therefore, symptom palliation is of great importance to improve patients' quality of life. Although it has been suggested that psychostimulants would be beneficial to patients with hypoactive delirium, there have been very few empirical reports so far. We report on a terminally ill cancer patient with hypoactive delirium caused by multi-organ failure, in whom methylphenidate was effective in improving the ability to maintain communication. This case highlights the efficacy of methylphenidate for hypoactive delirium in terminally ill cancer patients.
authors.affiliation: Seirei Hospice, Seirei Mikatabara Hospital, Shizuoka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Morita
authors.forename: H
authors.initials: H
authors.lastname: Otani
authors.forename: J
authors.initials: J
authors.lastname: Tsunoda
authors.forename: S
authors.initials: S
authors.lastname: Inoue
authors.forename: S
authors.initials: S
authors.lastname: Chihara
mesh_terms: D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D003693:Delirium / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008774:Methylphenidate / Q000627:therapeutic use*; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000150:complications; D010148:Intractable Pain / Q000188:drug therapy*; D010166:Palliative Care; D013274:Stomach Neoplasms / Q000473:pathology
chemical_list: D000697:Central Nervous System Stimulants; D008774:Methylphenidate