title: Evaluation of a new commercially available immunoglobulin M and immunoglobulin G immunochromatographic test for diagnosis of melioidosis infection.
abstract: An immunochromatographic test for the rapid determination of immunoglobulin M (IgM) and IgG antibodies to Burkholderia pseudomallei was evaluated by using sera from bacteriologically confirmed melioidosis patients and high-risk and clinically suspected patients, along with disease control groups. The sensitivities were 100 and 93% for the IgG and IgM tests, respectively, while the specificity was 95% for both assays. The test was rapid and simple to perform, with results obtained in 10 min.
authors.affiliation: PanBio Pty., Ltd., Windsor, Queensland, Australia.
authors.forename: A J
authors.initials: AJ
authors.lastname: Cuzzubbo
authors.forename: V
authors.initials: V
authors.lastname: Chenthamarakshan
authors.forename: J
authors.initials: J
authors.lastname: Vadivelu
authors.forename: S D
authors.initials: SD
authors.lastname: Puthucheary
authors.forename: D
authors.initials: D
authors.lastname: Rowland
authors.forename: P L
authors.initials: PL
authors.lastname: Devine
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood*; D016957:Burkholderia pseudomallei / Q000276:immunology*; D002845:Chromatography / Q000379:methods; D005069:Evaluation Studies as Topic; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008554:Melioidosis / Q000175:diagnosis* / Q000382:microbiology; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011933:Reagent Kits, Diagnostic