title: Prevention and prophylaxis of invasive fungal sinusitis in the immunocompromised patient.
abstract: Fungal infections are a leading cause of morbidity and mortality among immunocompromised patients. Invasive fungal sinusitis is a devastating complication of immunosuppression. Treatment options are limited and often ineffective, making prevention important. Measures to decrease environmental exposure, indications for antifungal prophylaxis, and limitations of current regimens are discussed.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USA.
authors.forename: P N
authors.initials: PN
authors.lastname: Malani
authors.forename: C A
authors.initials: CA
authors.lastname: Kauffman
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D006801:Humans; D016867:Immunocompromised Host; D009181:Mycoses; D010254:Paranasal Sinus Diseases / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
chemical_list: D000935:Antifungal Agents