title: Continuous ethanol production from concentrated wood hydrolysates in an internal membrane-filtration bioreactor.
abstract: Continuous culture for the production of ethanol from wood hydrolysate was carried out in an internal membrane-filtration bioreactor. The hydrolysate medium was sterilized at a relatively low temperature of 60 degrees C with the intention of reducing the formation of inhibitory compounds during the sterilization. The maximum ethanol concentration and productivity obtained in this study were 76.9 g/L and 16.9 g/L-h, respectively, which were much higher than those (57.2-67 g/L and 0.3-1.0 g/L-h) obtained in batch cultures using hydrolysate media sterilized at 60 degrees C. The productivity was also found to be much higher than that (6.7 g/L-h) obtained in a continuous cell retention culture using a wood hydrolysate sterilized at 121 degrees C. These results show that the internal membrane-filtration bioreactor in combination with low-temperature sterilization could be very effective for ethanol production from wood hydrolysate.
authors.affiliation: BioProcess Engineering Research Center and Department of Chemical Engineering, Korea Advanced Institute of Science and Technology, Taejon 305-701, Korea.
authors.forename: W G
authors.initials: WG
authors.lastname: Lee
authors.forename: B G
authors.initials: BG
authors.lastname: Park
authors.forename: Y K
authors.initials: YK
authors.lastname: Chang
authors.forename: H N
authors.initials: HN
authors.lastname: Chang
authors.forename: J S
authors.initials: JS
authors.lastname: Lee
authors.forename: S C
authors.initials: SC
authors.lastname: Park
mesh_terms: D019149:Bioreactors; D000431:Ethanol / Q000378:metabolism*; D005374:Filtration / Q000379:methods*; D006868:Hydrolysis; D008567:Membranes, Artificial; D012441:Saccharomyces cerevisiae; D013242:Sterilization; D013696:Temperature; D014934:Wood
chemical_list: D008567:Membranes, Artificial; D000431:Ethanol