Pyrrolidine inhibitors of human cytosolic phospholipase A(2).
Seno
K
K
Shionogi Research Laboratories, Shionogi & Company, Ltd., 12-4, Sagisu 5-chome, Fukushima-ku, Osaka 553-0002, Japan. kaoru.seno@shionogi.co.jp
Okuno
T
T
Nishi
K
K
Murakami
Y
Y
Watanabe
F
F
Matsuura
T
T
Wada
M
M
Fujii
Y
Y
Yamada
M
M
Ogawa
T
T
Okada
T
T
Hashizume
H
H
Kii
M
M
Hara
S
S
Hagishita
S
S
Nakamoto
S
S
Yamada
K
K
Chikazawa
Y
Y
Ueno
M
M
Teshirogi
I
I
Ono
T
T
Ohtani
M
M
D002460:Cell Line; D003600:Cytosol / Q000201:enzymology; D015232:Dinoprostone / Q000096:biosynthesis; D015777:Eicosanoids / Q000096:biosynthesis; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D017997:Leukotriene C4 / Q000096:biosynthesis; D010741:Phospholipases A / Q000037:antagonists & inhibitors*; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship
D015777:Eicosanoids; D004791:Enzyme Inhibitors; D011759:Pyrrolidines; D017997:Leukotriene C4; D010741:Phospholipases A; D015232:Dinoprostone