title: Preliminary results with the simultaneous use of implantable cardioverter defibrillators and permanent biventricular pacemakers: implications for device interaction and development.
abstract: We report our preliminary experience with the combined use of implantable cardioverter defibrillators (ICD) and biventricular pacemakers in six patients with heart failure and malignant ventricular arrhythmia. Two patients underwent ICD implantation for malignant ventricular arrhythmia after previous biventricular pacemaker implantation. One patient underwent biventricular pacemaker insertion for NYHA Class III heart failure after previous ICD implantation. Two patients underwent single device implantation. In the sixth patient, a combined implantation failed due to an inability to obtain a satisfactory left ventricular pacemaker lead position. The potential for device interaction was explored during implantation. In two patients a potentially serious interaction was discovered. Subsequent alterations in device configuration and programming prevented these interactions with long-term use. No complication of combined device use has been demonstrated during a mean follow-up of 2 months (range 1-4 months). Satisfactory ICD and pacemaker function has also been demonstrated. We conclude that combined device implantation may be feasible with currently available pacing technology and that further prospective studies are required in this area.
authors.affiliation: Department of Cardiology, Harefield Hospital, Uxbridge, Middlesex, United Kingdom.
authors.forename: S
authors.initials: S
authors.lastname: Walker
authors.forename: T
authors.initials: T
authors.lastname: Levy
authors.forename: S
authors.initials: S
authors.lastname: Rex
authors.forename: S
authors.initials: S
authors.lastname: Brant
authors.forename: V
authors.initials: V
authors.lastname: Paul
mesh_terms: D000328:Adult; D000368:Aged; D017147:Defibrillators, Implantable; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D014693:Ventricular Fibrillation / Q000628:therapy*