title: Synthesis and antiviral assays of some 2-substituted benzimidazole-N-carbamates.
abstract: Some 2-substituted benzimidazole-N-carbamates were synthesized and tested in vitro for antiviral activity. Two derivatives were active at noncytotoxic concentrations. The results confirmed the importance of the substituents at the 2-position of benzimidazole; an isopropylcarboxamide group led to the best activity.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università di Bologna, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Garuti
authors.forename: M
authors.initials: M
authors.lastname: Roberti
authors.forename: G
authors.initials: G
authors.lastname: Gentilomi
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D002219:Carbamates / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D002522:Chlorocebus aethiops; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D014709:Vero Cells
chemical_list: D000998:Antiviral Agents; D001562:Benzimidazoles; D002219:Carbamates