title: A 5-year review of 71 consecutive anterior skull base tumours.
abstract: Techniques used in craniofacial surgery have found extensive application in the management of skull base tumours. The improved exposure gained via osteotomies for facial disassembly has facilitated the en-bloc resection of tumours with clear surgical margins, and the advent of vascularised seals has significantly reduced the risk of meningeal contamination. We present our experience with the extirpation and reconstruction of 71 benign and malignant tumours of the anterior skull base over a 5-year period. Survival and functional outcome data are presented, with an emphasis on the wide range of pathologies and primary treatment strategies seen at presentation. Criteria used in flap selection and the role of prosthetics are discussed. Observations are offered on salvage surgery, demonstrating that excellent palliation can be achieved, even in cases with massive recurrent disease.
authors.affiliation: Craniofacial Unit, Chelsea and Westminster Hospital, London, UK.
authors.forename: M B
authors.initials: MB
authors.lastname: Kelly
authors.forename: N
authors.initials: N
authors.lastname: Waterhouse
authors.forename: D E
authors.initials: DE
authors.lastname: Slade
authors.forename: R
authors.initials: R
authors.lastname: Carr
authors.forename: D
authors.initials: D
authors.lastname: Peterson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016025:Bone Transplantation; D005260:Female; D006801:Humans; D008447:Maxillofacial Prosthesis; D008875:Middle Aged; D018579:Patient Selection; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000601:surgery*; D013524:Surgical Flaps; D016019:Survival Analysis