title: Adsorptive and electrochemical behaviors of estradiol valerate at a mercury electrode.
abstract: It was found that estradiol valerate could be adsorbed at a mercury electrode under open circuit. The adsorptive and electrochemical behaviors of estradiol valerate on a static mercury electrode were investigated by cyclic voltammetry, linear scan voltammetry and chronocoulometry. Based on this, a sensitive and selective adsorptive stripping square-wave voltammetric method was developed for the determination of estradiol valerate based on the optimization of solution conditions and electrochemical parameters. It was found that in a Britton-Robinson buffer solution containing 18% alcohol (pH 9.5), estradiol valerate gave a sensitive reductive peak at potential -1.29 V (vs. SCE) and the peak current was linear with the concentration of estradiol valerate in the range 2.0 x 10(-8)-2.5 x 10(-6) mol L-1. The detection limit was 1.1 x 10(-8) mol L-1. The interference of some common steroid estrogens was examined and it was found that they did not interfere in the determination of estradiol valerate in the present system.
authors.affiliation: Analytical and Testing Center, Fuzhou University, Fujian, China.
authors.forename: J P
authors.initials: JP
authors.lastname: Duan
authors.forename: G N
authors.initials: GN
authors.lastname: Chen
authors.forename: M L
authors.initials: ML
authors.lastname: Chen
authors.forename: X P
authors.initials: XP
authors.lastname: Wu
authors.forename: H Q
authors.initials: HQ
authors.lastname: Chen
mesh_terms: D000327:Adsorption; D004563:Electrochemistry; D004566:Electrodes; D004958:Estradiol / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry; D045166:Estradiol Congeners / Q000032:analysis* / Q000737:chemistry; D005260:Female; D006801:Humans; D008628:Mercury; D012680:Sensitivity and Specificity
chemical_list: D045166:Estradiol Congeners; D004958:Estradiol; D008628:Mercury