title: Clinico-immunological profile of juvenile rheumatoid arthritis at Chandigarh.
abstract: OBJECTIVE
  To study the clinical and immunological profile of children with juvenile rheumatoid arthritis (JRA).
  
  
  METHODS
  Retrospective hospital based study.
  
  
  METHODS
  Tertiary level center of North India.
  
  
  METHODS
  74 patients attending the Pediatric Rheumatology and Immunology Clinic over last 5 years.
  
  
  RESULTS
  The patients were aged between 9 months to 12 years with male female ratio of 1.8:1. Eleven (14.9%) patients had systemic onset JRA, 28 (37.8%) had polyarticular onset type and 35(47.3%) had pauciarticular onset type JRA. Uveitis was present only in one patient and rheumatoid nodules were present in 4(5.4%) patients. Rheumatoid factor was positive in 2(2.7%) and antinuclear antibody was present in one patient only. HLA-B27 was positive in 4 children. Two patients developed amyloidosis.
  
  
  CONCLUSIONS
  The clinico-immunological profile of JRA at Chandigarh appears to be some what different from that reported from other centers in India.
authors.affiliation: Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India.
authors.forename: S
authors.initials: S
authors.lastname: Singh
authors.forename: M
authors.initials: M
authors.lastname: Salaria
authors.forename: L
authors.initials: L
authors.lastname: Kumar
authors.forename: R
authors.initials: R
authors.lastname: Minz
authors.forename: U
authors.initials: U
authors.lastname: Datta
authors.forename: S
authors.initials: S
authors.lastname: Sehgal
mesh_terms: D017677:Age Distribution; D001171:Arthritis, Juvenile / Q000145:classification* / Q000453:epidemiology* / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution