The ins and outs of EBV infection.
Epstein-Barr virus (EBV) infects almost the entire adult population of the world. The success of this virus appears to be based on its ability to infect the B cell, rather than any other cell type. We review EBV B-cell tropism, and discuss the mechanisms by which the virus may gain access to, and egress from, B cells in the normal host.
Faulkner
G C
GC
Depts of Medical Microbiology and Pathology, University of Edinburgh Medical School, Teviot Place, Edinburgh, UK EH8 9AG.
Krajewski
A S
AS
Crawford
D H
DH
D001402:B-Lymphocytes / Q000276:immunology / Q000473:pathology / Q000821:virology*; D004847:Epithelial Cells / Q000821:virology; D020031:Epstein-Barr Virus Infections / Q000276:immunology / Q000473:pathology / Q000821:virology*; D004854:Herpesvirus 4, Human / Q000276:immunology / Q000472:pathogenicity* / Q000502:physiology*; D006801:Humans; D009928:Organ Specificity; D012463:Saliva / Q000821:virology; D014779:Virus Replication