title: Combined revascularization and microvascular free tissue transfer for limb salvage: a six-year experience.
abstract: Atherosclerotic vascular disease causing extensive tissue loss of the lower extremities often results in primary amputation. Combined revascularization and free tissue transfer has been described as a method of extending limb salvage to these patients. The durability of this combined procedure remains unknown, thus the objective of this report is to describe the immediate and long-term results in a series collected over 6 years. From 1992 to 1998, 15 patients with a mean age of 60 years underwent combined revascularization and free tissue transfer. Mean ulcer size measured 45 cm(2) for a mean duration of 7.4 months preoperatively and 12 patients had exposed bone or tendon. Vascular reconstruction included popliteal (3), tibial (6), and pedal (6) bypass with concomitant myocutaneous free flap, using mostly rectus abdominis or latissimus dorsi muscle. There were no perioperative deaths. One patient suffered a nonfatal myocardial infarction. Two patients had a postoperative wound hematoma and one required vascular graft revision. Patients were followed for 4 to 75 months (mean = 23 months). Four patients have required amputations (3 early, 1 late), three of whom had preoperative renal failure. The limb salvage rate has been 72% at 36 months,
authors.affiliation: Division of Vascular, UCLA Center for the Health Sciences, Los Angeles, CA 90095, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Quiñones-Baldrich
authors.forename: V S
authors.initials: VS
authors.lastname: Kashyap
authors.forename: M B
authors.initials: MB
authors.lastname: Taw
authors.forename: B L
authors.initials: BL
authors.lastname: Markowitz
authors.forename: J P
authors.initials: JP
authors.lastname: Watson
authors.forename: T D
authors.initials: TD
authors.lastname: Reil
authors.forename: W W
authors.initials: WW
authors.lastname: Shaw
mesh_terms: D001161:Arteriosclerosis / Q000150:complications* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007511:Ischemia / Q000601:surgery*; D007866:Leg / Q000098:blood supply* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012307:Risk Factors; D012737:Sex Factors; D013524:Surgical Flaps; D014656:Vascular Surgical Procedures