title: Functional MRI in double cortex: functionality of heterotopia.
abstract: A 12-year-old boy with epilepsy and subcortical laminar heterotopia (band heterotopia) underwent a functional MRI protocol to study voluntary motor activity in the hand. Finger tapping produced an activation of a contralateral limited and focused frontal cortical area both in the subcortical band heterotopia and the overlying cortex. Despite its epileptogenic activity, subcortical laminar heterotopia seems to be responsible for part of the functional activity of the brain. This has to be pointed out for epilepsy surgery resecting cortical dysplasia.
authors.affiliation: Department of Paediatric Neurology, Raymond Poincaré Hospital, Garches, France. jean-marc.pinard@rpc.ap-hop-paris.fr
authors.forename: J
authors.initials: J
authors.lastname: Pinard
authors.forename: A
authors.initials: A
authors.lastname: Feydy
authors.forename: R
authors.initials: R
authors.lastname: Carlier
authors.forename: N
authors.initials: N
authors.lastname: Perez
authors.forename: L
authors.initials: L
authors.lastname: Pierot
authors.forename: Y
authors.initials: Y
authors.lastname: Burnod
mesh_terms: D000200:Action Potentials; D002540:Cerebral Cortex / Q000002:abnormalities*; D002648:Child; D002828:Choristoma / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology*; D006225:Hand / Q000294:innervation; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009043:Motor Activity; D009068:Movement