Comparative study of conservative resection and radical operation for thyroid carcinomas.
OBJECTIVE
To compare mortality and morbidity in management of thyroid cancers by total lobectomy (C-R) and near-total thyroidectomy (R-O) and to relate pathological subtype to prognosis.


METHODS
A retrospective study of patients with thyroid cancers that were managed during an eleven-year period.


METHODS
Jos University Teaching Hospital, Nigeria.


METHODS
A total of 44 patients who underwent C-R (n = 26) and R-O (n = 18) were studied.


METHODS
A total of 509 goitrous specimens including the excised thyroid cancers were histopathologically studied.


METHODS
Cases were analysed for mortality and morbidity data in the two groups during a partial follow-up period of two years.


RESULTS
Mortality figures for C-R was 4% versus 11 for R-O. Postoperative haemorrhage occurred in 14% for C-R versus six for R-O. Similarly, bilateral vocal cord paralysis occurred in 11% versus 22; voice changes in 11% versus 33, transitory hypoparathyroidism 8% versus 50, local recurrence in 18% versus eleven. Hypothyroidism occurred in all patients undergoing R-O and stitch granuloma in 11% of patients in C-R group versus six for R-O. Follicular carcinoma constituted 59% of the total number thyroid cancers with papillary cancer constituting 35%.


CONCLUSIONS
C-R is recommended as the operation of choice for thyroid cancers.
Igun
G O
GO
Department of Surgery, Jos University Teaching Hospital, Nigeria.
Obekpa
P O
PO
Ugwu
B T
BT
Nwana
E J
EJ
D018263:Adenocarcinoma, Follicular / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D000328:Adult; D002291:Carcinoma, Papillary / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D017052:Hospital Mortality; D006785:Hospitals, University; D006801:Humans; D006961:Hyperparathyroidism / Q000209:etiology; D007037:Hypothyroidism / Q000209:etiology; D008297:Male; D009017:Morbidity; D009367:Neoplasm Staging; D009549:Nigeria / Q000453:epidemiology; D011379:Prognosis; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D013965:Thyroidectomy / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000209:etiology