title: Long-term persistence of a discotheque-associated invasive Neisseria meningitidis group C strain as proven by pulsed-field gel electrophoresis and porA gene sequencing.
abstract: A cluster of a Neisseria meningitidis serogroup C strain causing invasive disease was investigated. Five out of seven cases were associated with a particular discotheque. The strains were indistinguishable, as revealed by pulsed-field gel electrophoresis and sequencing of variable regions of the porA gene, but caused strikingly different clinical presentations during 5 months.
authors.affiliation: Department of Medical Microbiology, Malmö University Hospital, Lund University, S-205 02 Malmö, Sweden. kristian.riesbeck@mikrobiol.mas.lu.se
authors.forename: K
authors.initials: K
authors.lastname: Riesbeck
authors.forename: P
authors.initials: P
authors.lastname: Orvelid-Mölling
authors.forename: H
authors.initials: H
authors.lastname: Fredlund
authors.forename: P
authors.initials: P
authors.lastname: Olcén
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003615:Dancing; D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008589:Meningococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D008875:Middle Aged; D009345:Neisseria meningitidis / Q000145:classification / Q000235:genetics / Q000472:pathogenicity*; D018272:Porins / Q000235:genetics*; D013548:Sweden / Q000453:epidemiology
chemical_list: D018272:Porins; C057699:porin protein, Neisseria