Novel catalytic asymmetric sulfoxidation in water using the hypervalent iodine reagent iodoxybenzene.
A new catalytic asymmetric oxidation of sulfides to sulfoxides in water using the hypervalent iodine(V) reagent iodoxybenzene (PhIO2) has been developed. This methodology is distinctly different from the previously reported use of cyclodextrins or biological catalysts and provides a new route to asymmetric sulfoxidation in water.
Tohma
H
H
Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan.
Takizawa
S
S
Morioka
H
H
Maegawa
T
T
Kita
Y
Y
D002384:Catalysis; D007202:Indicators and Reagents; D007462:Iodobenzenes / Q000737:chemistry*; D010084:Oxidation-Reduction; D013454:Sulfoxides / Q000138:chemical synthesis*; D014867:Water
D007202:Indicators and Reagents; D007462:Iodobenzenes; D013454:Sulfoxides; D014867:Water; C057598:iodoxybenzene