[Effect of perilymphatic fistula on distortion product otoacoustic emissions in guinea pigs].
Perilymphatic fistula was induced in 11 healthy guinea pigs to study its effects on distortion product otoacoustic emissions (DPOAEs). DPOAE amplitudes decreased significantly right after formation of the fistula (P < 0.01), and recurred to near pretreatment level in animals whose fistula healed. The amplitude remained below pretreatment level 18 days after fistulization in those animals whose fistula failed to heal. Under light microscope, the organ of Corti was seen normal. The authors feel that DPOAEs may be helpful in detecting perilymphatic fistula.
Wang
L
L
Navy General Hospital, Beijing.
Jiang
W
W
Jiang
P
P
D000161:Acoustic Stimulation / Q000379:methods; D000818:Animals; D003055:Cochlear Microphonic Potentials; D005402:Fistula / Q000175:diagnosis* / Q000503:physiopathology; D006168:Guinea Pigs; D017084:Otoacoustic Emissions, Spontaneous; D010469:Perceptual Distortion / Q000502:physiology*; D010498:Perilymph