title: Does the Centers for Disease Control's NNIS system risk index stratify patients undergoing cardiothoracic operations by their risk of surgical-site infection?
abstract: BACKGROUND
  In 1991, the Centers for Disease Control and Prevention devised the National Nosocomial Infection Surveillance (NNIS) System risk index to stratify populations of surgical patients by the risk of acquiring surgical-site infections (SSIs).
  
  
  OBJECTIVE
  To determine whether the NNIS risk index adequately stratifies a population of cardiothoracic surgery patients by the risk of developing SSI.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  The University of Iowa Hospitals and Clinics, a 900-bed, midwestern, tertiary-care hospital.
  
  
  METHODS
  201 patients with SSIs identified by prospective infection control surveillance and 398 controls matched by age, gender, type of procedure, and date of procedure. All patients underwent cardiothoracic operative procedures between November 1990 and January 1994.
  
  
  RESULTS
  The SSI rate was 7.8%. Seventy-four percent of cases and 80% of controls had a NNIS risk index score of 1; 24% of cases and 16% of controls had a score of 2 (P=.05). Patients with a NNIS risk score > or =2 were 1.8 times more likely to develop an SSI than those with a NNIS score <2 (odds ratio, 1.83; 95% confidence interval, 1.14-2.94, P=.01). The duration of the procedure was the only component of the index that stratified the population by risk of SSI.
  
  
  CONCLUSIONS
  The risk of SSI after cardiothoracic operations increases as the NNIS risk index score increases. However, this index only dichotomized the patient population on the basis of the procedure duration. More research is needed to develop a risk index that adequately stratifies the risk of SSI after cardiothoracic operations.
authors.affiliation: Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, USA.
authors.forename: M C
authors.initials: MC
authors.lastname: Roy
authors.forename: L A
authors.initials: LA
authors.lastname: Herwaldt
authors.forename: R
authors.initials: R
authors.lastname: Embrey
authors.forename: K
authors.initials: K
authors.lastname: Kuhns
authors.forename: R P
authors.initials: RP
authors.lastname: Wenzel
authors.forename: T M
authors.initials: TM
authors.lastname: Perl
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002487:Centers for Disease Control and Prevention, U.S.; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000453:epidemiology*; D006746:Hospital Bed Capacity, 500 and over; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007484:Iowa; D008875:Middle Aged; D010361:Patients / Q000145:classification*; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000517:prevention & control; D019616:Thoracic Surgical Procedures / Q000009:adverse effects*; D014481:United States