[Methods of verification of aging theories].
The methodology of verification of theories of aging belongs to the most crucial problems in theoretical and experimental gerontology. Extensive number of hypotheses of the nature of the basic mechanisms of aging exists on the field of theoretical gerontology. This situation claims the development of the effective methodology of verification. Traditional ways of the verification were indirect and insufficient. The progress in theoretical gerontology provides the possibility to verify the theories in more exact way. Survey of the contemporary state in the theories of aging and available methods of verification is presented in the paper. The tools of verification derived from survival curves and mortality curves are analyzed and discussed. Further the tools of verification derived from biomarkers of aging and batteries of biological age are presented.
Doubal
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Katedra biofyziky a fyzikální chemie Farmaceutické fakulty Univerzity Karlovy, Hradec Králové.
Klemera
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P
D000375:Aging / Q000502:physiology*; D015415:Biomarkers; D005853:Geriatrics; D006801:Humans; D016019:Survival Analysis
D015415:Biomarkers