title: Urinary tract infection in diabetic patients.
abstract: OBJECTIVE
  The aim of the study was to compare the epidemiological, microbiological and clinical features of diabetic patients with urinary tract infection (UTI) to those of nondiabetic ones.
  
  
  METHODS
  A prospective study was performed on 490 consecutive patients with proven UTI. The patients were studied on the basis of a specific questionnaire and hospital records.
  
  
  RESULTS
  Of 490 enrolled patients, 89 (18.1%) had diabetes mellitus. The mean age of diabetics and nondiabetics was respectively 64.9 +/- 13.2 (SD) and 54.4 +/- 23.3 years. Most diabetics had asymptomatic bacteriuria and had undergone bladder catheterization more frequently than the nondiabetics. The most frequent causative agents of UTI in diabetics and nondiabetics were: E. coli (respectively, 56.1 vs. 56.8%), Proteus sp. (7.9% vs. 7.2%), Pseudomonas sp. (6.7 vs. 8.2%), Enterococcus sp. (6.7 vs. 7.2%). More than 50% of the isolated Pseudomonas sp. strains in both groups were resistant to gentamicin, piperacillin and norfloxacin. Both diabetics (52.8%) and nondiabetics (42.2%) had recurrent UTI during the follow-up period; the difference in the incidences did not reach statistical significance.
  
  
  CONCLUSIONS
  No significant differences in epidemiological, clinical and microbiological evaluated features of diabetics and nondiabetics were pointed out, except for the higher frequency of bladder catheterization of diabetics than nondiabetics. However, the eradication of UTI seemed to be more difficult in diabetics than in nondiabetics.
authors.affiliation: Dipartimento di Patologia Sperimentale, Biotecnologie Mediche, Infettiologia ed Epidemiologia, Università di Pisa, Italia. m.bonadio@int.med.unipi.it
authors.forename: M
authors.initials: M
authors.lastname: Bonadio
authors.forename: M
authors.initials: M
authors.lastname: Meini
authors.forename: C
authors.initials: C
authors.lastname: Gigli
authors.forename: B
authors.initials: B
authors.lastname: Longo
authors.forename: A
authors.initials: A
authors.lastname: Vigna
mesh_terms: D001437:Bacteriuria / Q000453:epidemiology / Q000382:microbiology; D016022:Case-Control Studies; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000453:epidemiology; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014546:Urinary Catheterization; D014552:Urinary Tract Infections / Q000453:epidemiology* / Q000382:microbiology