title: Surnames and the Y chromosome.
abstract: A randomly ascertained sample of males with the surname "Sykes" was typed with four Y-chromosome microsatellites. Almost half the sample shared the same Y-chromosome haplotype, which has not been observed in control samples either from the same geographic region or from the United Kingdom as a whole. This points to a single surname founder for extant Sykes males, even though written sources had predicted multiple origins. The distribution of other Sykes Y-chromosome haplotypes were not significantly different from those in controls and may be accounted for by the historical accumulation of nonpaternity during the past 700 years, in which case the average rate estimate is 1.3%/generation. If this pattern is reproduced with other surnames, it may have important forensic and genealogical applications.
authors.affiliation: Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom. bryan.sykes@imm.ox.ac.uk
authors.forename: B
authors.initials: B
authors.lastname: Sykes
authors.forename: C
authors.initials: C
authors.lastname: Irven
mesh_terms: D005220:Fathers; D018703:Founder Effect; D005787:Gene Frequency / Q000235:genetics; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics; D009275:Names; D010334:Paternity; D015203:Reproducibility of Results; D012494:Sampling Studies; D006113:United Kingdom; D014998:Y Chromosome / Q000235:genetics*