title: Morbidity, mortality and local anaesthesia.
abstract: Two cases of local anaesthetic overdose and death are described. The patients, a four-year-old child and a 68-year old female, received local anaesthetic doses greatly in excess of those recommended. Their overdose reactions are described as well as subsequent management. The paper reviews the causes of local anaesthetic overdose, its signs and symptoms, and the recommended management of these reactions. Specific discussion as to the cause of death of these two patients and of the means to prevent such occurrences in the future concludes the paper.
authors.affiliation: School of Dentistry, University of Southern California, USA. malamed@hsc.usc.edu
authors.forename: S F
authors.initials: SF
authors.lastname: Malamed
mesh_terms: D000368:Aged; D000766:Anesthesia, Dental / Q000009:adverse effects*; D000772:Anesthesia, Local / Q000009:adverse effects*; D000779:Anesthetics, Local / Q000008:administration & dosage* / Q000506:poisoning*; D002675:Child, Preschool; D062787:Drug Overdose; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D000779:Anesthetics, Local