Generalized pustular psoriasis or drug-induced toxic pustuloderma? The use of patch testing.
Pustular psoriasis is a rare but serious form of psoriasis. Clinically it may be difficult to differentiate from a pustular drug reaction. We report a case of a generalized pustular eruption triggered by exposure to amoxycillin in a patient with chronic psoriasis. Patch testing to 1% and 5% amoxycillin preparation confirmed a delayed hypersensitivity reaction.
Whittam
L R
LR
St. John's Institute of Dermatology, St. Thomas' Hospital, London, UK.
Wakelin
S H
SH
Barker
J N
JN
D000658:Amoxicillin / Q000009:adverse effects*; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D010406:Penicillins / Q000009:adverse effects*; D011565:Psoriasis / Q000175:diagnosis*
D010406:Penicillins; D000658:Amoxicillin