title: Improving outcome after traumatic brain injury--progress and challenges.
abstract: This article describes the rapid advances in the head injury field which have taken place within the professional lifetime of many doctors in practice today. These have led to a better understanding of what happens in the injured brain and how these events might be manipulated to achieve better outcomes. Clinical tools we now take for granted, like the CT scanner and the Glasgow Coma Scale, were new developments 25 years ago. They provided a foundation on which clinicians and basic scientists could build what we now know: what to assess in the patient, how to respond to certain findings, what imaging to do, how to plan treatment rationally, how to minimise brain damage at different stages after injury, how to predict and measure outcome, what disabled survivors need, and how to organise the service to do the greatest good for the most people. Some of these topics raise as many questions as answers. The head injury field may be broad but it has essential unity. At one extreme, some patients have a life-threatening illness where the acts and omissions of the clinical team can powerfully influence not only survival but its quality. Later the drama of the acute phase gives way to the 'hidden disabilities' of the long-term deficits which so many survivors have. At the other end of the severity spectrum is the relatively vast number of people who suffer an apparently mild head injury, a few of whom deteriorate and need urgent treatment, and many of whom have unspectacular but, nevertheless, disabling problems. The article attempts to address this broad canvas. Clinicians, neuroscientists, policy makers, and service users must work together to address the major scientific, individual, and population challenges posed by head injury. Much has already been achieved, but much remains to be done, especially in translating 'what we know' into 'what we do'.
authors.affiliation: Ninewells Hospital, Dundee, UK.
authors.forename: D
authors.initials: D
authors.lastname: Gentleman
mesh_terms: D001930:Brain Injuries / Q000145:classification / Q000175:diagnosis / Q000628:therapy; D004635:Emergency Medicine / Q000458:organization & administration; D019317:Evidence-Based Medicine; D006801:Humans; D010360:Patient Transfer; D017410:Practice Guidelines as Topic; D012106:Research; D012151:Resuscitation; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome