ST segment and T wave alternans in a patient with Brugada syndrome.
We describe a patient with Brugada syndrome in whom J point and ST-segment elevation in leads V1 and V2 were augmented by atrial pacing and intravenous administration of propranolol or cibenzoline. Significant T wave alternans with a 2:1 appearance of terminal negative T wave was observed in the absence and presence of atrial pacing after the administration of cibenzoline. The cellular mechanism responsible for T wave alternans, beat-to-beat appearance of terminal negative T wave and augmented J point and ST-segment elevation is discussed.
Tada
H
H
Division of Cardiology, Gunma Prefectural Cardiovascular Center, Japan.
Nogami
A
A
Shimizu
W
W
Naito
S
S
Nakatsugawa
M
M
Oshima
S
S
Taniguchi
K
K
D002037:Bundle-Branch Block / Q000503:physiopathology*; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D013577:Syndrome; D014693:Ventricular Fibrillation / Q000503:physiopathology*