title: MR in vivo imaging of oxygen suppression effect of soft contact lens on the human cornea.
abstract: The O(2) suppression effect of a soft contact lens on the human cornea was measured using dynamic magnetic resonance imaging (MRI) of the anterior chamber transcorneally exposed to O(2). Dynamic T(1)-weighted fast spin echo imaging of anterior chambers (TR = 2 s, TE = 15 ms, 5-mm slice) was performed both before and during oxygen supply to a full goggle placed on the face of volunteers wearing a soft contact lens on one eye and nothing on the other eye as a control. Within 15 min after O(2) administration, significantly lower intensity changes were obtained in the anterior chambers of the eyes with the contact lens than in those of the eyes without one, suggesting that dynamic MRI of the anterior chamber transcorneally exposed to O(2) can be used to evaluate the O(2) suppression effect of a soft contact lens on the cornea.
authors.affiliation: Department of Radiology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Saito
authors.forename: T
authors.initials: T
authors.lastname: Obata
authors.forename: K
authors.initials: K
authors.lastname: Hirono
authors.forename: T
authors.initials: T
authors.lastname: Iwasawa
authors.forename: T
authors.initials: T
authors.lastname: Yoshida
authors.forename: S
authors.initials: S
authors.lastname: Matsubara
mesh_terms: D000867:Anterior Chamber / Q000033:anatomy & histology / Q000378:metabolism; D003263:Contact Lenses, Hydrophilic; D003315:Cornea / Q000378:metabolism*; D005069:Evaluation Studies as Topic; D005135:Eye Protective Devices; D006801:Humans; D008279:Magnetic Resonance Imaging; D008422:Materials Testing; D010100:Oxygen / Q000378:metabolism*; D010539:Permeability; D011237:Predictive Value of Tests
chemical_list: D010100:Oxygen