title: [Thromboembolic diseases in children].
abstract: The incidence of thromboembolic diseases in children is increasing, probably as a consequence of medical progress and modern intensive care. Due to lack of scientific evidence, clinical recommendations for treatment of children are mainly based on opinions and extrapolations from adult medicine. This article presents current concepts of thromboembolic diseases in children, based on a review of the literature. Characteristic features are presented and differences between the disease in adults and children are outlined. Guidelines for antithrombotic treatment are provided. We suggest that screening for thrombophilic disorders should be performed on wide indications, and that modern principles of treatment in adult medicine should also be applied for children with thromboembolic diseases.
authors.affiliation: Barneklinikken, Rikshospitalet, Oslo.
authors.forename: H
authors.initials: H
authors.lastname: Holmström
authors.forename: T
authors.initials: T
authors.lastname: Rootwelt
mesh_terms: D000328:Adult; D002648:Child; D002675:Child, Preschool; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D008403:Mass Screening; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D013923:Thromboembolism / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology; D015912:Thrombolytic Therapy
chemical_list: D005343:Fibrinolytic Agents; D006493:Heparin