title: [Focal echogenic splenic involvement in malignant lymphoma: a diagnostic problem].
abstract: OBJECTIVE
  The aim of our study was to describe clinical data, frequency of the findings, sonographic patterns, confirmation of diagnosis, and differential diagnosis of focal echorich splenic lymphoma involvement.
  
  
  METHODS
  During the last 20 years a focal splenic lesion was found in 178 patients with malignant lymphoma. Echorich splenic lesions were seen in 11 out of 178 cases (6.2%).
  
  
  METHODS
  Splenic size, echomorphology of lesions, size and number of lesions, and presentation during sonographic follow-up examination were presented.
  
  
  RESULTS
  Echorich infiltrates of the spleen were predominantly seen in patients with low grade Non-Hodgkin-Lymphoma (9 out of 11), the size of lesions mostly was less than 3 cm in diameter (9 out of 11), the underlying splenic size was over 8 x 20 cm in 9 out of 11 patients. Diagnosis was confirmed by sonographic follow-up (n = 11) and autopsy (n = 1).
  
  
  CONCLUSIONS
  Echorich splenic lymphoma involvement is a rare event and is characterised by a variable presentation during follow-up. Up to date the clinic significance of our observation is still unclear.
authors.affiliation: Medizinische Universitätsklinik, Marburg.
authors.forename: J
authors.initials: J
authors.lastname: Riera-Knorrenschild
authors.forename: C
authors.initials: C
authors.lastname: Görg
authors.forename: N
authors.initials: N
authors.lastname: Dennhardt
authors.forename: I
authors.initials: I
authors.lastname: Restrepo
authors.forename: A
authors.initials: A
authors.lastname: Neubauer
mesh_terms: D000368:Aged; D001344:Autopsy; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging* / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D012189:Retrospective Studies; D013154:Spleen / Q000000981:diagnostic imaging* / Q000473:pathology; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography