[Candida albicans fungemia with pulmonary localization treated with fluconazole. A case report].
We report a case of Candida albicans fungemia complicated by a pulmonary localization in a non-immunocompromised patient. Complete recovery was obtained after a long course of high-dose fluconazole in spite of in vitro resistance of the Candida to fluconazole. The usefulness of fluconazole therapy, the best dosage regimen and the in vitro and in vivo correlations are discussed.
Thomas
F
F
Service de réanimation polyvalente, Hôpital des Diaconesses, 18 rue du Sergent Bauchat, 75012 Paris, France.
Mebtouche
B
B
Clavier
H
H
Kalfon
P
P
D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D000935:Antifungal Agents / Q000627:therapeutic use*; D002177:Candidiasis / Q000188:drug therapy* / Q000209:etiology* / Q000382:microbiology; D002405:Catheterization, Central Venous / Q000009:adverse effects; D003428:Cross Infection / Q000188:drug therapy* / Q000209:etiology* / Q000382:microbiology; D004352:Drug Resistance, Microbial; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use*; D016469:Fungemia / Q000188:drug therapy* / Q000209:etiology* / Q000382:microbiology; D006801:Humans; D008172:Lung Diseases, Fungal / Q000188:drug therapy* / Q000209:etiology* / Q000382:microbiology; D010289:Parenteral Nutrition, Total / Q000009:adverse effects; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D015725:Fluconazole