title: Breast cancer in dense breast: detection with contrast-enhanced dynamic MR imaging.
abstract: The purpose of this study was to identify contrast enhancement patterns of dense breast parenchyma and to investigate the ability of dynamic magnetic resonance imaging (MRI) to detect cancer in the dense breast. Thirty-two patients with breast cancer in dense breast underwent gadolinium-enhanced dynamic MRI. The detectability of cancer by dynamic MRI, mammography, and physical examination was compared. Two parenchymal enhancement patterns could be identified. One was increasingly multiple patchy enhancement found predominantly in the periphery (type A), and the other was faint enhancement without any nodular opacification (type B). Type A was thought to reflect severe proliferative fibrocystic change (PFC). For both patterns, the detection rate of primary cancers by dynamic MRI was found to be superior to that by other modalities. Dynamic MRI also could detect multifocal cancers, which could not be found with other modalities, although the detectability of these small cancers might be reduced in patients with severe PFC.
authors.affiliation: Department of Radiology, Kanazawa University School of Medicine, Ishikawa, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kawashima
authors.forename: O
authors.initials: O
authors.lastname: Matsui
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
authors.forename: M
authors.initials: M
authors.lastname: Kadoya
authors.forename: M
authors.initials: M
authors.lastname: Tawara
authors.forename: A
authors.initials: A
authors.lastname: Nonomura
authors.forename: M
authors.initials: M
authors.lastname: Noguchi
authors.forename: T
authors.initials: T
authors.lastname: Takashima
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology; D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis / Q000473:pathology; D002293:Adenocarcinoma, Scirrhous / Q000175:diagnosis / Q000473:pathology; D000328:Adult; D000368:Aged; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis / Q000473:pathology; D003287:Contrast Media; D005260:Female; D005348:Fibrocystic Breast Disease / Q000175:diagnosis / Q000473:pathology; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging; D008327:Mammography; D008875:Middle Aged; D011237:Predictive Value of Tests
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA