Effects of pulsed magnetic energy on a microsurgically transferred vessel.
This article reports the findings of a study that attempted to elucidate whether pulsed magnetic energy stimulates neovascularization in vivo, using a microsurgically created arterial loop model in a prospective randomized trial of 108 rats (n = 12/group). Pulsed magnetic energies of 0.1 and 2.0 gauss were applied immediately postoperatively and for 4, 8, and 12 weeks, respectively, with a statistically significant increase in neovascularization among the treated animals compared with control rats. The study provides a starting point for future study and evaluation of the stimulation of angiogenesis with the use of pulsed magnetic energy and suggests a possible use of this modality to increase the quality of revascularized tissue.
Roland
D
D
Department of Plastic and Reconstructive Surgery at the Albert Einstein College of Medicine, Bronx, NY, USA.
Ferder
M
M
Kothuru
R
R
Faierman
T
T
Strauch
B
B
D000818:Animals; D004574:Electromagnetic Fields; D008297:Male; D018919:Neovascularization, Physiologic / Q000502:physiology*; D011182:Postoperative Care; D051381:Rats; D017207:Rats, Sprague-Dawley; D013524:Surgical Flaps / Q000098:blood supply*