title: CT manifestations of respiratory syncytial virus infection in lung transplant recipients.
abstract: OBJECTIVE
  The purpose of our study was to evaluate CT findings during respiratory syncytial virus (RSV) infection in lung transplant recipients and to identify sequelae.
  
  
  METHODS
  Thirty-nine CT scans prior to, during, and following acute infection in 10 lung transplant recipients were reviewed. Abnormalities that were new from baseline observations and occurred within 4 weeks of diagnosis were defined as acute. Chronic findings were defined as those present >4 weeks after diagnosis.
  
  
  RESULTS
  Findings in nine patients were ground-glass (seven), air-space (five), and tree-in-bud (four) opacities and acute bronchial dilatation (four) and wall thickening (four). Patients lacked pleural effusions or lymph node enlargement. Five of seven patients with follow-up exams had new air trapping (three), persistent bronchial dilatation (three), and thickening (two). Three and 2 of the 10 patients developed bronchiolitis obliterans syndrome and obliterative bronchiolitis, respectively.
  
  
  CONCLUSIONS
  During acute infection, patients commonly had ground-glass opacities but lacked pleural effusions and lymph node enlargement. There can be chronic sequelae after infection.
authors.affiliation: Department of Radiology, Massachusetts General Hospital, Boston 02114, USA. jko@partners.org
authors.forename: J P
authors.initials: JP
authors.lastname: Ko
authors.forename: J A
authors.initials: JA
authors.lastname: Shepard
authors.forename: M W
authors.initials: MW
authors.lastname: Sproule
authors.forename: B
authors.initials: B
authors.lastname: Trotman-Dickenson
authors.forename: E A
authors.initials: EA
authors.lastname: Drucker
authors.forename: L C
authors.initials: LC
authors.lastname: Ginns
authors.forename: J C
authors.initials: JC
authors.lastname: Wain
authors.forename: T C
authors.initials: TC
authors.lastname: McLoud
mesh_terms: D000208:Acute Disease; D000280:Administration, Inhalation; D000328:Adult; D001706:Biopsy; D001989:Bronchiolitis Obliterans / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D016867:Immunocompromised Host; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology / Q000821:virology; D016040:Lung Transplantation / Q000009:adverse effects / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000000981:diagnostic imaging* / Q000473:pathology; D018357:Respiratory Syncytial Virus Infections / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D012189:Retrospective Studies; D012254:Ribavirin / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed
chemical_list: D012254:Ribavirin