title: Functional assessment of chest wall integrity after methylmethacrylate reconstruction.
abstract: BACKGROUND
  All patients with extensive resection of the anterolateral chest wall and the sternum followed by reconstruction with methylmethacrylate substitutes were assessed prospectively 6 months after the operation to delineate chest wall integrity with pulmonary function and cine-magnetic resonance imaging.
  
  
  METHODS
  Twenty-six patients underwent chest wall reconstruction by use of methylmethacrylate between 1994 and 1998 due to primary tumors in 35%, metastases in 27%, T3 lung cancer in 19%, and debridement for radionecrosis and osteomyelitis in 19% of patients. Three to eight ribs were resected and additional sternum resection was performed in 39% of patients.
  
  
  RESULTS
  There was no 30-day mortality. All patients were extubated after the operation without need for reintubation. Prosthesis dislocation occurred in 1 patient and infection in 2 patients during follow-up. Nineteen patients (73%) suffered no restrictions of daily activities. Clinical examination revealed normal shoulder girdle function in 77% of patients. There was no significant difference between preoperative and postoperative FEV1 (forced expiratory volume in 1 second) measurements in patients with lobectomy or wedge resections. Cinemagnetic resonance imaging revealed concordant chest wall movements during respiration in 92% of patients without paradoxical movements or implant dislocations being observed.
  
  
  CONCLUSIONS
  Large defects of the anterolateral chest wall and sternum can be reconstructed efficiently with methylmethacrylate substitutes with minimal morbidity and excellent cosmetic and functional outcome.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, University Hospital, University of Bern, Switzerland.
authors.forename: D
authors.initials: D
authors.lastname: Lardinois
authors.forename: M
authors.initials: M
authors.lastname: Müller
authors.forename: M
authors.initials: M
authors.lastname: Furrer
authors.forename: A
authors.initials: A
authors.lastname: Banic
authors.forename: M
authors.initials: M
authors.lastname: Gugger
authors.forename: T
authors.initials: T
authors.lastname: Krueger
authors.forename: H B
authors.initials: HB
authors.lastname: Ris
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D020366:Methylmethacrylate; D008875:Middle Aged; D011446:Prospective Studies; D019736:Prostheses and Implants; D019651:Plastic Surgery Procedures / Q000379:methods*; D020127:Recovery of Function; D019616:Thoracic Surgical Procedures / Q000379:methods*
chemical_list: D020366:Methylmethacrylate