Genomic and genetic research on bursate nematodes: significance, implications and prospects.
Molecular genetic research on parasitic nematodes (order Strongylida) is of major significance for many fundamental and applied areas of medical and veterinary parasitology. The advent of gene technology has led to some progress for this group of nematodes, particularly in studying parasite systematics, drug resistance and population genetics, and in the development of diagnostic assays and the characterisation of potential vaccine and drug targets. This paper gives an account of the molecular biology and genetics of strongylid nematodes, mainly of veterinary socio-economic importance, indicates the implications of such research and gives a perspective on genome research for this important parasite group, in light of recent technological advances and knowledge of the genomes of other metazoan organisms.
Gasser
R B
RB
Department of Veterinary Science, The University of Melbourne, 250 Princes Highway, Werribee, Victoria, Australia. r.gasser@vet.unimelb.edu.au
Newton
S E
SE
D000818:Animals; D004275:DNA, Ribosomal / Q000737:chemistry; D015870:Gene Expression; D014644:Genetic Variation; D016678:Genome; D009348:Nematoda / Q000235:genetics*
D004275:DNA, Ribosomal