A malignant rhabdoid tumor of the kidney occurring concurrently with a brain tumor: report of a case.
Malignant rhabdoid tumor of the kidney (MRTK) is one of the most lethal neoplasms to occur in young infants. Cases of MRTK accompanying an embryonal tumor in the central nervous system have occasionally been described. We present herein an interesting case of MRTK that was clinically diagnosed preoperatively. A male infant aged 6 months with both a midline brain tumor and a renal neoplasm was transferred to our institution. Although roentgenographic evaluation suggested that the renal lesion was a Wilms' tumor, midkine (MK), a growth and differentiation factor characteristically present in the urine of patients with Wilms' tumor, was not detected. A preoperative diagnosis of MRTK was established based on the lack of urinary MK in addition to the typical clinical features of the young age and the concurrent brain tumor.
Adachi
Y
Y
Department of Pediatric Surgery, Faculty of Medicine, Kagoshima University, Japan.
Takamatsu
H
H
Noguchi
H
H
Tahara
H
H
Fukushige
T
T
Takasaki
T
T
Yoshida
A
A
Kamenosono
A
A
Kikuchi
J
J
Asatani
M
M
Kawakami
K
K
D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000473:pathology*; D018335:Rhabdoid Tumor / Q000175:diagnosis / Q000473:pathology*; D009396:Wilms Tumor / Q000175:diagnosis / Q000473:pathology*