title: Reaction of dogs' teeth to root canal filling with mineral trioxide aggregate or a glass ionomer sealer.
abstract: This study was conducted to observe the reaction of apical tissues of dogs' teeth after root canal filling with gutta-percha and mineral trioxide aggregate (MTA) or a glass ionomer (Ketac-Endo) as a sealer. The root canals were instrumented and filled by the lateral condensation technique with the sealers studied. Animals were killed 6 months later, and the specimens were removed and prepared for histological analysis. Results showed no inflammatory reaction of apical tissue and total closure of the apical foramen of all the teeth sealed with MTA. The teeth sealed with Ketac-Endo showed two cases of partial closure and different degrees of chronic inflammatory reaction. In conclusion, MTA exhibited better biological properties than Ketac-Endo.
authors.affiliation: Department of Endodontics, Faculdade de Odontologia de Araçatuba, UNESP, São Paulo, Brazil.
authors.forename: R
authors.initials: R
authors.lastname: Holland
authors.forename: V
authors.initials: V
authors.lastname: de Souza
authors.forename: M J
authors.initials: MJ
authors.lastname: Nery
authors.forename: J A
authors.initials: JA
authors.lastname: Otoboni Filho
authors.forename: P F
authors.initials: PF
authors.lastname: Bernabé
authors.forename: E
authors.initials: E
authors.lastname: Dezan Júnior
mesh_terms: D017607:Aluminum Compounds / Q000494:pharmacology*; D000818:Animals; D017610:Calcium Compounds / Q000494:pharmacology*; D003739:Dental Cementum / Q000187:drug effects; D003809:Dentin, Secondary / Q000187:drug effects; D004285:Dogs; D004338:Drug Combinations; D005899:Glass Ionomer Cements / Q000494:pharmacology*; D010087:Oxides / Q000494:pharmacology*; D010486:Periapical Tissue / Q000187:drug effects*; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D017640:Silicates / Q000494:pharmacology*; D019227:Tooth Apex / Q000187:drug effects*
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D005899:Glass Ionomer Cements; C074934:Ketac Endo; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate