Diversity of homology-dependent gene silencing strategies in fungi.
The experimental introduction of DNA in fungi has revealed a variety of gene inactivation strategies triggered in response to the presence of homologous nucleic acid sequences. These homology effects reveal distinct classes of gene inactivation resulting from hypermutation or relying on regulatory mechanisms that operate at either the transcriptional or the post-transcriptional level.
Faugeron
G
G
Institut Jacques Monod, UMR 7592: CNRS/Université Paris, Paris, 75251, France. faugeron@ijm.jussieu.fr
D001203:Ascomycota / Q000166:cytology / Q000201:enzymology / Q000235:genetics*; D002843:Chromatin / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015825:Chromosomes, Fungal / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D019175:DNA Methylation; D015254:DNA Modification Methylases / Q000378:metabolism; D015966:Gene Expression Regulation, Fungal / Q000235:genetics*; D020868:Gene Silencing / Q000502:physiology*; D008540:Meiosis / Q000235:genetics; D009492:Neurospora crassa / Q000166:cytology / Q000201:enzymology / Q000235:genetics* / Q000254:growth & development; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic / Q000235:genetics
D002843:Chromatin; D015254:DNA Modification Methylases