Role of cold receptors and menthol in thirst, the drive to breathe and arousal.
Menthol is widely used in candy, chewing gum, toothpastes, cigarettes and common cold medications. Menthol has been shown to stimulate cold receptors in the mouth and nose. The present paper puts forward the hypothesis that menthol, by its effects on oral and nasal cold receptors, may influence thirst, the drive to breathe, and arousal. The satisfying effects of menthol on thirst and breathing, together with an effect on arousal, may explain the popularity of menthol and account for the very large amount of menthol-containing products that are consumed each day.
Eccles
R
R
Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Wales.
D001143:Arousal / Q000187:drug effects*; D005421:Flavoring Agents / Q000494:pharmacology*; D006801:Humans; D008610:Menthol / Q000494:pharmacology*; D009055:Mouth; D009666:Nose; D012119:Respiration / Q000187:drug effects*; D013823:Thermoreceptors / Q000187:drug effects / Q000502:physiology*; D013894:Thirst / Q000187:drug effects* / Q000502:physiology
D005421:Flavoring Agents; D008610:Menthol