Effect of digoxin imprinting in adolescence on the sexual behavior of adult rats.
Four-time 3 micrograms digoxin treatment of male rats at puberty (in six weeks old rats) significantly increased the libido of rats (number of intromissions) and reduced the number of ejaculations, two months after the treatments (in three and a half months old rats). In female rats the Meyerson index and lordosis quotient were not significantly decreased. The experiment calls attention to the wide-ranging imprinting effect of digoxin which was also demonstrated earlier after prenatal (maternal) treatment. The experiment also supports the male sexual potency influencing effect of digoxin treatment, previously supposed in men.
Karabélyos
C
C
Department of Genetics, Cell and Immunobiology, Semmelweis University of Medicine, Budapest, Hungary.
Csaba
G
G
D000375:Aging / Q000502:physiology; D000818:Animals; D002316:Cardiotonic Agents / Q000494:pharmacology*; D004077:Digoxin / Q000494:pharmacology*; D005260:Female; D008297:Male; D011187:Posture; D051381:Rats; D017208:Rats, Wistar; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D012741:Sexual Maturation / Q000187:drug effects
D002316:Cardiotonic Agents; D004077:Digoxin