Myelination in the splenium of the corpus callosum in adult male and female rats.
Previous work reported increases in the number of myelinated axons in the splenium of the rat corpus callosum between 25 and 60 days of age. In the present study, we quantified the area occupied by myelinated axons using a light microscopic point counting technique at 60, 120 and 180 days. Myelinated axons increased across these ages (p=0.001). Thus, myelination of the rat corpus callosum persists well into adulthood.
Nuñez
J L
JL
Neuroscience Program and Department of Psychology, University of Illinois at Champaign-Urbana, 603 E Daniel Street, Champaign, IL, USA.
Nelson
J
J
Pych
J C
JC
Kim
J H
JH
Juraska
J M
JM
D000367:Age Factors; D000818:Animals; D002452:Cell Count; D003337:Corpus Callosum / Q000166:cytology* / Q000254:growth & development / Q000502:physiology*; D005260:Female; D008297:Male; D009186:Myelin Sheath / Q000502:physiology*; D009413:Nerve Fibers, Myelinated / Q000502:physiology*; D051381:Rats; D020318:Rats, Long-Evans