title: Polymorphism of the cytochrome P450 (CYP) 2C9 gene in Japanese epileptic patients: genetic analysis of the CYP2C9 locus.
authors.affiliation: Division of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Imai
authors.forename: I
authors.initials: I
authors.lastname: Ieiri
authors.forename: K
authors.initials: K
authors.lastname: Mamiya
authors.forename: S
authors.initials: S
authors.lastname: Miyahara
authors.forename: H
authors.initials: H
authors.lastname: Furuumi
authors.forename: E
authors.initials: E
authors.lastname: Nanba
authors.forename: M
authors.initials: M
authors.lastname: Yamane
authors.forename: Y
authors.initials: Y
authors.lastname: Fukumaki
authors.forename: H
authors.initials: H
authors.lastname: Ninomiya
authors.forename: N
authors.initials: N
authors.lastname: Tashiro
authors.forename: K
authors.initials: K
authors.lastname: Otsubo
authors.forename: S
authors.initials: S
authors.lastname: Higuchi
mesh_terms: D000483:Alleles; D019943:Amino Acid Substitution; D001189:Aryl Hydrocarbon Hydroxylases; D065729:Cytochrome P-450 CYP2C9; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics*; D004827:Epilepsy / Q000097:blood / Q000188:drug therapy / Q000235:genetics*; D005091:Exons / Q000235:genetics; D006801:Humans; D007564:Japan; D009154:Mutation; D010672:Phenytoin / Q000031:analogs & derivatives / Q000097:blood / Q000627:therapeutic use; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D039181:Steroid 16-alpha-Hydroxylase; D013250:Steroid Hydroxylases / Q000235:genetics*
chemical_list: C001419:hydroxyphenytoin; D010672:Phenytoin; D003577:Cytochrome P-450 Enzyme System; D013250:Steroid Hydroxylases; C450260:CYP2C9 protein, human; D065729:Cytochrome P-450 CYP2C9; D001189:Aryl Hydrocarbon Hydroxylases; D039181:Steroid 16-alpha-Hydroxylase