title: Granulomatous nephritis as a complication of intrarenal bacille Calmette-Guérin therapy.
abstract: A case of granulomatous nephritis after intrarenal bacille Calmette-Guérin (BCG) therapy is reported. High fever greater than 38.5 degrees C lasted for 1 month, without response to conservative therapy. Standard nephroureterectomy was subsequently carried out. Histopathologic findings from the surgical specimen were compatible with BCG-induced granulomatous nephritis. The use of a syringe pump for retrograde instillation of BCG was thought to be the major cause of this severe complication.
authors.affiliation: Department of Urology, Shimada Municipal Hospital, Shizuoka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Soda
authors.forename: D
authors.initials: D
authors.lastname: Hori
authors.forename: H
authors.initials: H
authors.lastname: Onishi
authors.forename: M
authors.initials: M
authors.lastname: Miyakawa
mesh_terms: D000368:Aged; D001500:BCG Vaccine / Q000008:administration & dosage* / Q000009:adverse effects*; D002278:Carcinoma in Situ / Q000628:therapy*; D002295:Carcinoma, Transitional Cell / Q000628:therapy*; D002408:Catheters, Indwelling; D010478:Chemotherapy, Cancer, Regional Perfusion / Q000009:adverse effects*; D005260:Female; D005334:Fever / Q000209:etiology; D006099:Granuloma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007668:Kidney; D009393:Nephritis / Q000209:etiology* / Q000473:pathology; D014516:Ureteral Neoplasms / Q000628:therapy*; D001749:Urinary Bladder Neoplasms / Q000628:therapy*
chemical_list: D001500:BCG Vaccine