A polymorphic tetranucleotide repeat in the CYP19 gene and male breast cancer.
The CYP19 gene codes for the aromatase enzyme that is involved in the synthesis of oestrogens. This case-control study examines the relationship between a tetranucleotide repeat sequence in the CYP19 gene and the development of male breast cancer. No significant differences were found between male breast cancer cases and controls.
Young
I E
IE
University of Edinburgh, Department of Pathology, Molecular Medicine Centre, Western General Hospital, UK.
Kurian
K M
KM
MacKenzie
M A
MA
Kunkler
I H
IH
Cohen
B B
BB
Hooper
M L
ML
Wyllie
A H
AH
Steel
C M
CM
D001141:Aromatase / Q000235:genetics*; D018567:Breast Neoplasms, Male / Q000235:genetics*; D016022:Case-Control Studies; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D016133:Polymerase Chain Reaction
D001141:Aromatase