title: HXB/Ipcv and BXH/Cub recombinant inbred strains of the rat: strain distribution patterns of 632 alleles.
abstract: The HXB/Ipcv and BXH/Cub sets of recombinant inbred (RI) strains were derived from the spontaneously hypertensive rats (SHR/OlaIpcv) and normotensive Brown Norway (BN-Lx/Cub) rats. The RI strains were produced as a model system for genetic and correlation analysis of spontaneous hypertension and other risk factors of cardiovascular disease such as insulin resistance and dyslipidemia. The RI strains were phenotyped in multiple hemodynamic and metabolic traits. In the current study, we describe strain distribution patterns of 632 genetic markers.
authors.affiliation: Institute of Physiology, Academy of Sciences of the Czech Republic, Prague. pravenec@biomed.cas.cz
authors.forename: M
authors.initials: M
authors.lastname: Pravenec
authors.forename: V
authors.initials: V
authors.lastname: Kren
authors.forename: D
authors.initials: D
authors.lastname: Krenová
authors.forename: V
authors.initials: V
authors.lastname: Bíla
authors.forename: V
authors.initials: V
authors.lastname: Zídek
authors.forename: M
authors.initials: M
authors.lastname: Simáková
authors.forename: A
authors.initials: A
authors.lastname: Musilová
authors.forename: H A
authors.initials: HA
authors.lastname: van Lith
authors.forename: L F
authors.initials: LF
authors.lastname: van Zutphen
mesh_terms: D000483:Alleles; D000818:Animals; D002318:Cardiovascular Diseases / Q000235:genetics; D005819:Genetic Markers; D020022:Genetic Predisposition to Disease; D051381:Rats; D011914:Rats, Inbred BN / Q000235:genetics*; D011918:Rats, Inbred SHR / Q000235:genetics*; D011919:Rats, Inbred Strains / Q000235:genetics*; D011995:Recombination, Genetic; D012307:Risk Factors; D013045:Species Specificity
chemical_list: D005819:Genetic Markers