Nucleic acids: theory and computer simulation, Y2K.
Molecular dynamics simulations on DNA and RNA that include solvent are now being performed under realistic environmental conditions of water activity and salt. Improvements to force-fields and treatments of long-range interactions have significantly increased the reliability of simulations. New studies of sequence effects, axis bending, solvation and conformational transitions have appeared.
Beveridge
D L
DL
Chemistry Department, Molecular Biophysics Program, Wesleyan University, Middletown, CT 06459, USA. dbeveridge@wesleyan.edu
McConnell
K J
KJ
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003198:Computer Simulation; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry; D007477:Ions; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry; D009843:Oligoribonucleotides / Q000737:chemistry; D012313:RNA / Q000737:chemistry; D012997:Solvents; D013816:Thermodynamics; D014867:Water
D007477:Ions; D009838:Oligodeoxyribonucleotides; D009843:Oligoribonucleotides; D012997:Solvents; D014867:Water; D012313:RNA; D004247:DNA