title: [Mechanism of B-A transition in the DNA molecule with elastic interaction between sugars and nitrous bases].
abstract: A two-component model with elastic interactions between subsystems was proposed, which describes conformational transitions in the DNA molecule. The model is applicable for the description of B-->A transitions in the DNA molecule. It is shown that conformational excitations propagate along the macromolecule via stable topological solutions having a definite velocity. Two types of solutions can be distinguished: exciting and reducing. The exciting solution realizes the transition of sugar from the ground state to a metastable state; in this process, the distance between complementary bases increases. The reducing solution is formed behind the exciting solution and realizes a reverse transition.
authors.affiliation: Institute of Physics of Molecules and Crystals, Ufa Research Center, Russian Academy of Sciences, Russia.
authors.forename: V O
authors.initials: VO
authors.lastname: Ponomarev
authors.forename: E S
authors.initials: ES
authors.lastname: Shikhovtseva
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D011687:Purines / Q000737:chemistry*; D011743:Pyrimidines / Q000737:chemistry*
chemical_list: D002241:Carbohydrates; D011687:Purines; D011743:Pyrimidines; D004247:DNA