title: Tobacco withdrawal signs and symptoms among women with and without a history of depression.
abstract: A past history of depression is associated with a decreased likelihood of quitting smoking. Tobacco withdrawal may be a mechanism through which depression history impedes smoking cessation. This research examined the influence of depression history on unmedicated tobacco withdrawal signs (polysomnographic measures of sleep) and symptoms (self-reported urge, negative affect, hunger, and sleep) among women (N= 13). Depression history was associated with differential withdrawal-induced changes in several REM sleep parameters. Self-report and other polysomnography (sleep fragmentation, slow-wave sleep) measures displayed statistically significant withdrawal effects but did not discriminate between depression history groups. These results suggest that REM sleep parameters may be sensitive to differential tobacco withdrawal responses that are not readily apparent through self-reported symptoms.
authors.affiliation: Group Health Cooperative, Department of Health Services, University of Washington School of Public Health and Community Medicine, Seattle 98101, USA. wetter.d@ghc.org
authors.forename: D W
authors.initials: DW
authors.lastname: Wetter
authors.forename: C L
authors.initials: CL
authors.lastname: Carmack
authors.forename: C B
authors.initials: CB
authors.lastname: Anderson
authors.forename: C A
authors.initials: CA
authors.lastname: Moore
authors.forename: C A
authors.initials: CA
authors.lastname: De Moor
authors.forename: P M
authors.initials: PM
authors.lastname: Cinciripini
authors.forename: M
authors.initials: M
authors.lastname: Hirshkowitz
mesh_terms: D000328:Adult; D000368:Aged; D003866:Depressive Disorder / Q000523:psychology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D017286:Polysomnography; D012044:Regression Analysis; D012890:Sleep / Q000187:drug effects; D012894:Sleep Stages / Q000187:drug effects; D012893:Sleep Wake Disorders / Q000523:psychology; D012895:Sleep, REM / Q000187:drug effects; D016540:Smoking Cessation / Q000523:psychology*; D013375:Substance Withdrawal Syndrome / Q000523:psychology*