mRNA stability in eukaryotes.
During the past two years, the role of the proteins HuR and hnRNP D in regulated mRNA degradation in humans has become clearer, and a putative mRNA deadenylase, DAN or PARN, has been identified. In yeast, the relationship between translation and mRNA turnover is clearer, but the mRNA decapping process has turned out to be unexpectedly complex.
Mitchell
P
P
Institute of Cell & Molecular Biology, University of Edinburgh, Edinburgh, EH9 3JR, UK.
Tollervey
D
D
D000818:Animals; D005057:Eukaryotic Cells / Q000378:metabolism*; D006801:Humans; D020871:RNA Stability; D012333:RNA, Messenger / Q000378:metabolism*
D012333:RNA, Messenger