title: ST segment and T wave alternans in a patient with Brugada syndrome.
abstract: We describe a patient with Brugada syndrome in whom J point and ST-segment elevation in leads V1 and V2 were augmented by atrial pacing and intravenous administration of propranolol or cibenzoline. Significant T wave alternans with a 2:1 appearance of terminal negative T wave was observed in the absence and presence of atrial pacing after the administration of cibenzoline. The cellular mechanism responsible for T wave alternans, beat-to-beat appearance of terminal negative T wave and augmented J point and ST-segment elevation is discussed.
authors.affiliation: Division of Cardiology, Gunma Prefectural Cardiovascular Center, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Tada
authors.forename: A
authors.initials: A
authors.lastname: Nogami
authors.forename: W
authors.initials: W
authors.lastname: Shimizu
authors.forename: S
authors.initials: S
authors.lastname: Naito
authors.forename: M
authors.initials: M
authors.lastname: Nakatsugawa
authors.forename: S
authors.initials: S
authors.lastname: Oshima
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
mesh_terms: D002037:Bundle-Branch Block / Q000503:physiopathology*; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D013577:Syndrome; D014693:Ventricular Fibrillation / Q000503:physiopathology*