A toxoplasmic uveitis case of a 60-year-old male in Korea.
A toxoplasmic uveitis case was reported on the focus of impairment of pathological findings and serological antibody titers after chemotherapy. A chief complaint of a 60-year-old male was a decreased and blurred vision in his right eye for 2 weeks after experiencing tremendous stress and fatigue. A steroid therapy for 3 weeks was not effective and the retinal lesion became necrotic. Anti-Toxoplasma gondii antibody titer was checked to be a strong positive by both ELISA and indirect latex agglutination assay (ILA). He was treated with Fansidar F for 8 weeks. His vision improved as the necrotic lesion healed by scarring, but the antibody titers still remained very high without any signs of negative conversion. It is suggested to be a recurrent case of the past asymptomatic infection by presumed immune suppression caused by excessive stress.
Kim
M H
MH
Department of Ophthalmology, Catholic University of Korea, College of Medicine, Seoul, Korea.
Choi
Y K
YK
Park
Y K
YK
Nam
H W
HW
D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D000962:Antimalarials / Q000627:therapeutic use; D015415:Biomarkers / Q000032:analysis; D004338:Drug Combinations; D006801:Humans; D007108:Immune Tolerance; D007723:Korea; D008297:Male; D008875:Middle Aged; D011739:Pyrimethamine / Q000627:therapeutic use; D012008:Recurrence; D013413:Sulfadoxine / Q000627:therapeutic use; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis; D014605:Uveitis / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*
D000913:Antibodies, Protozoan; D000962:Antimalarials; D015415:Biomarkers; D004338:Drug Combinations; C001205:fanasil, pyrimethamine drug combination; D013413:Sulfadoxine; D011739:Pyrimethamine