Transcriptional control: The benefits of selective insulation.
In eukaryotes, cis-regulatory sequences are often a long way away from the transcription start site, and interactions between regulatory elements can be blocked by 'insulator' sequences. A novel type of cis-regulatory element has now been found that selectively permits some interactions across insulators.
Müller
J
J
Max-Planck-Institut für Entwicklungsbiologie, Tübingen, 72076, Germany. juerg.mueller@tuebingen.mpg.de
D000818:Animals; D001665:Binding Sites; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000378:metabolism; D029721:Drosophila Proteins; D005786:Gene Expression Regulation; D018398:Homeodomain Proteins / Q000235:genetics*; D019476:Insect Proteins / Q000235:genetics*; D009687:Nuclear Proteins / Q000378:metabolism; D012097:Repressor Proteins; D014157:Transcription Factors; D014158:Transcription, Genetic
C062393:Abd-B proteins, Drosophila; D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D018398:Homeodomain Proteins; D019476:Insect Proteins; D009687:Nuclear Proteins; D012097:Repressor Proteins; D014157:Transcription Factors; C066177:Ubx protein, Drosophila; C083738:su(Hw) protein, Drosophila