title: [The treatment of central nervous system neoplasms].
abstract: From August 1993 to March 1998 30 children (13 females and 17 males) at the age of 1-14 with central nervous system tumours were treated in Paediatric Hematology and Oncology Hospital in Wrocław. In 11 patients we diagnosed medulloblastoma, in 4 ependymoma, 6 astrocytoma, 2 oligodendroglioma and in 7 other types of tumours. The histological diagnosis of 2 cases with tumours localized in the brain trunk was not available. All patients were directed to the chemotherapy after the surgery. Complete resection was achieved in 13 out of 30 patients. The chemotherapy was proceeded according to SIOP regimen. Children older than 3 years received additional radiotherapy. The effectiveness of treatment was controlled by constant neurological examinations with computed tomography and ultrasonography. The rate of failures was 10 patients with local recurrences and 1 patient with drug toxicity. 17 children remain still in observation--among them 5 are treated with chemotherapy and 2 present the progression of disease.
authors.affiliation: Katedry i Kliniki Hematologii i Chorób Rozrostowych Dzieci Akademii Medycznej we Wrocławiu.
authors.forename: D
authors.initials: D
authors.lastname: Wójcik
authors.forename: T
authors.initials: T
authors.lastname: Dyrda
authors.forename: W
authors.initials: W
authors.lastname: Pietras
mesh_terms: D000293:Adolescent; D016543:Central Nervous System Neoplasms / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D018450:Disease Progression; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D017211:Treatment Failure