A case of chronic lymphocytic leukemia with a constitutional pericentric inversion of chromosome 1.
Chronic lymphocytic leukemia (CLL) has been reported to be associated with various chromosomal aberrations, the most common being trisomy 12 and structural rearrangements involving 13q, 11q, and 17p. We present a case of CLL with a constitutional pericentric inversion of chromosome 1.
Palanduz
S
S
Division of Medical Genetics, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Cefle
K
K
Aktan
M
M
Tutkan
G
G
Oztürk
S
S
Pekçelen
Y
Y
D002503:Centromere / Q000235:genetics*; D002871:Chromosome Banding; D007446:Chromosome Inversion; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics* / Q000473:pathology; D008214:Lymphocytes / Q000378:metabolism / Q000473:pathology; D008297:Male; D008875:Middle Aged