[Syndrome of inappropriate macrophage activation associated with infantile visceral leishmaniasis].
Hemophagocytosis has already been in cases of visceral leishmaniasis and thus may complicate search for diagnosis. We report a case of hemophagocytosis in a 20 month-old boy presenting with fever, hepatosplenomegaly, pancytopenia and coagulopathy. An initial diagnosis of kala-azar was refuted because of absence of biological inflammatory syndrome and negativity of bone-marrow aspiration. Specific serology for visceral leishmaniasis become positive. The boy was given stibogluconate for 21 days; he improves gradually with complete remission.
Thabet
F
F
Service de Pédiatrie, Hôpital Farhat Hached, Sousse.
Tabarki
B
B
Fehem
R
R
Yacoub
M
M
Selmi
H
H
Essoussi
A S
AS
D003937:Diagnosis, Differential; D015616:Histiocytosis, Non-Langerhans-Cell / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007223:Infant; D007898:Leishmaniasis, Visceral / Q000150:complications*; D008297:Male