Low whole blood glutathione levels in pregnancies complicated by preeclampsia and diabetes.
Nineteen pregnancies with preeclampsia, 16 with diabetic preeclampsia and 29 control pregnancies were analyzed with regards to maternal total glutathione. In preeclampsia, maternal total glutathione levels were lower than in normal pregnancy (P<0.001). Also, diabetic preeclamptics showed low total glutathione levels as compared to preeclampsia (P<0.05) and control (P<0.001). These findings indicate decreased detoxificating or free radical scavenging capacity in pregnancies complicated by preeclampsia and diabetes.
Kharb
S
S
Department of Biochemistry, Pt. B.D. Sharma PGIMS, Rohtak, India.
D000328:Adult; D001724:Birth Weight; D003404:Creatinine / Q000097:blood; D005260:Female; D005865:Gestational Age; D005978:Glutathione / Q000097:blood* / Q000172:deficiency; D006801:Humans; D007231:Infant, Newborn; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood*; D012016:Reference Values; D014527:Uric Acid / Q000097:blood
D014527:Uric Acid; D003404:Creatinine; D005978:Glutathione