title: H19 and IGF-2 allele-specific expression in hepatoblastoma.
abstract: Patterns of allele-specific expression of H19 and insulin-like growth factor-2 (IGF-2) were examined in tissue obtained from 30 children diagnosed with hepatoblastoma. All informative tumours demonstrated monoallelic expression of H19. In contrast, variable patterns of allele-specific expression of IGF-2 were seen in tumours from children of different ages.
authors.affiliation: Department of Pediatrics, University of Minnesota Cancer Center, Minneapolis, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Ross
authors.forename: G A
authors.initials: GA
authors.lastname: Radloff
authors.forename: S M
authors.initials: SM
authors.lastname: Davies
mesh_terms: D000483:Alleles; D001483:Base Sequence; D002648:Child; D002675:Child, Preschool; D017931:DNA Primers; D005260:Female; D018197:Hepatoblastoma / Q000235:genetics*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007335:Insulin-Like Growth Factor II / Q000235:genetics*; D008113:Liver Neoplasms / Q000235:genetics*; D008297:Male; D009124:Muscle Proteins / Q000235:genetics*; D062085:RNA, Long Noncoding; D022661:RNA, Untranslated
chemical_list: D017931:DNA Primers; C094335:H19 long non-coding RNA; D009124:Muscle Proteins; D062085:RNA, Long Noncoding; D022661:RNA, Untranslated; D007335:Insulin-Like Growth Factor II