RNA on the road to myelin.
In oligodendrocytes some mRNAs are transported from the perikaryon to the distal processes and localized in the myelin compartment where they are translated. This review describes the cis-acting signals and trans-acting factors that mediate intracellular trafficking of myelin basic protein (MBP) RNA, the prototype for such mRNAs in myelinating glia.
Barbarese
E
E
Departments of Neurology, Graduate Programs, University of Connecticut Health Center, Farmington, CT, USA.
Brumwell
C
C
Kwon
S
S
Cui
H
H
Carson
J H
JH
D000818:Animals; D001692:Biological Transport / Q000502:physiology; D006801:Humans; D009186:Myelin Sheath / Q000378:metabolism*; D009836:Oligodendroglia / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism*
D012333:RNA, Messenger