Epilepsy in adolescents: hormonal considerations.
A correlation between seizure disorders and reproductive hormones has been recognized for centuries. Through basic scientific and clinical studies, an understanding of the interrelationships has become clearer. Puberty does not increase the incidence of seizures. Catamenial seizures, when diagnosed, may be improved with hormonal manipulation. Therapeutic regimens for those treated unsuccessfully with antiepileptic therapy need continued validation. Patients with seizure disorders have an increased incidence of menstrual disorders. Hormonal contraception is not contraindicated in this population, yet requires a more cautious approach to avoid failure.
Logsdon-Pokorny
V K
VK
Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, UT 84098, USA.
D000293:Adolescent; D003278:Contraceptives, Oral, Hormonal / Q000008:administration & dosage; D004827:Epilepsy / Q000150:complications / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology*; D005260:Female; D012739:Gonadal Steroid Hormones / Q000378:metabolism* / Q000627:therapeutic use; D006801:Humans; D008597:Menstrual Cycle; D008599:Menstruation Disturbances / Q000209:etiology / Q000503:physiopathology; D011627:Puberty; D012307:Risk Factors
D003278:Contraceptives, Oral, Hormonal; D012739:Gonadal Steroid Hormones