Long-term persistence of a discotheque-associated invasive Neisseria meningitidis group C strain as proven by pulsed-field gel electrophoresis and porA gene sequencing.
A cluster of a Neisseria meningitidis serogroup C strain causing invasive disease was investigated. Five out of seven cases were associated with a particular discotheque. The strains were indistinguishable, as revealed by pulsed-field gel electrophoresis and sequencing of variable regions of the porA gene, but caused strikingly different clinical presentations during 5 months.
Riesbeck
K
K
Department of Medical Microbiology, Malmö University Hospital, Lund University, S-205 02 Malmö, Sweden. kristian.riesbeck@mikrobiol.mas.lu.se
Orvelid-Mölling
P
P
Fredlund
H
H
Olcén
P
P
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003615:Dancing; D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008589:Meningococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D008875:Middle Aged; D009345:Neisseria meningitidis / Q000145:classification / Q000235:genetics / Q000472:pathogenicity*; D018272:Porins / Q000235:genetics*; D013548:Sweden / Q000453:epidemiology
D018272:Porins; C057699:porin protein, Neisseria