title: Pyogenic granuloma of the tongue early after allogeneic bone marrow transplantation for multiple myeloma.
abstract: Oral complications occur frequently after bone marrow transplantation (BMT). Some of them are caused by regimen-related toxicity of the preparative regimen, and others by infections. In addition, oral tissues are targets of graft-versus-host disease (GVHD). Oral granulomatous lesions are not a common complication after BMT, and are especially rare on the tongue. Such rare lesions reported in the literature, developed late after BMT with oral chronic GVHD. We present here a patient who developed pyogenic granuloma of the tongue early after allogeneic BMT done for multiple myeloma. Regimen-related mucositis, oral acute GVHD, the administration of cyclosporine A, and the preexisting macroglossia might be responsible for the formation of granuloma.
authors.affiliation: Department of Hematology, International Medical Center of Japan, Tokyo. ycanda-tky@umin.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Kanda
authors.forename: C
authors.initials: C
authors.lastname: Arai
authors.forename: A
authors.initials: A
authors.lastname: Chizuka
authors.forename: M
authors.initials: M
authors.lastname: Suguro
authors.forename: T
authors.initials: T
authors.lastname: Hamaki
authors.forename: R
authors.initials: R
authors.lastname: Yamamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Yamauchi
authors.forename: T
authors.initials: T
authors.lastname: Matsuyama
authors.forename: N
authors.initials: N
authors.lastname: Takezako
authors.forename: Y
authors.initials: Y
authors.lastname: Shirai
authors.forename: A
authors.initials: A
authors.lastname: Miwa
authors.forename: K
authors.initials: K
authors.lastname: Iwasaki
authors.forename: M
authors.initials: M
authors.lastname: Nasu
authors.forename: A
authors.initials: A
authors.lastname: Togawa
mesh_terms: D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D017809:Fatal Outcome; D005260:Female; D017789:Granuloma, Pyogenic / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000628:therapy*; D014060:Tongue Diseases / Q000209:etiology*; D014184:Transplantation, Homologous