title: Dedifferentiated chondrosarcoma of the larynx.
abstract: A 74-year-old man with a history of a chondroid lesion of the larynx noted an enlarging neck mass. Axial CT showed a large expansile lesion arising from the left thyroid cartilage. Multiple rings and arcs with relatively intact cortex indicated a chondroid lesion. Irregularity of the anterolateral margin abutted a prominent soft-tissue component. The specimen obtained from fine needle aspiration was suggestive of a malignant fibrous histiocytoma. After further resection, the final diagnosis was dedifferentiated chondrosarcoma. A new soft-tissue component or rapid growth of the mass can be indicative of a diagnosis of dedifferentiated chondrosarcoma.
authors.affiliation: Department of Radiology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, USA.
authors.forename: O
authors.initials: O
authors.lastname: Sakai
authors.forename: H D
authors.initials: HD
authors.lastname: Curtin
authors.forename: W C
authors.initials: WC
authors.lastname: Faquin
authors.forename: R L
authors.initials: RL
authors.lastname: Fabian
mesh_terms: D000368:Aged; D002813:Chondrosarcoma / Q000000981:diagnostic imaging* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D014057:Tomography, X-Ray Computed