Population study of Aymara Amerindians for the PCR-DNA polymorphisms HUMTH01, HUMVWA31A, D3S1358, D8S1179, D18S51, D19S253, YNZ22 and HLA-DQalpha.
Allele and genotype frequencies for eight DNA polymorphisms (HUMTH01, HUMVWA31A, D3S1358, D8S1179, D18S51, D19S253, YNZ22 and HLA-DQalpha) were determined in a population sample of Aymara Indians from Bolivia using PCR. No deviations of the observed allelic frequencies from Hardy-Weinberg equilibrium were found for all the systems studied. Significant differences in the allele frequencies were found between the Aymara and Quechua populations only for HUMVWA31A, which suggests a certain degree of genetic differentiation between the two populations.
Gené
M
M
Forensic Genetics Laboratory, Legal Medicine Department, School of Medicine, University of Barcelona, Spain. mgene@medicina.ub.es
Moreno
P
P
Borrego
N
N
Piqué
E
E
Xifró
A
A
Fuentes
M
M
Bert
F
F
Corella
A
A
Pérez-Pérez
A
A
Turbón
D
D
Corbella
J
J
Huguet
E
E
D000483:Alleles; D004247:DNA / Q000235:genetics*; D005787:Gene Frequency; D005819:Genetic Markers; D006683:HLA-DQ Antigens / Q000235:genetics*; D059848:HLA-DQ alpha-Chains; D006801:Humans; D007199:Indians, South American / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D014446:Tyrosine 3-Monooxygenase / Q000235:genetics*
D005819:Genetic Markers; D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; C069050:HLA-DQA1 antigen; D004247:DNA; D014446:Tyrosine 3-Monooxygenase