title: Bacterial, viral and parasitic aetiology of paediatric diarrhoea in the highlands of Papua New Guinea.
abstract: Enteropathogens and clinical features associated with diarrhoea were investigated in 1526 children admitted over a 5-year period to the paediatric ward of a hospital in the highlands of Papua New Guinea. Overall, a recognized pathogen was isolated from 39 per cent of the children admitted with diarrhoea. The most commonly isolated agents were rotavirus (23 per cent), Shigella spp. (13 per cent), Campylobacter spp. (12 per cent), Cryptosporidium parvum (10 per cent) and enteropathogenic Escherichia coli (8 per cent). The clearest clinical associations were rotavirus with vomiting, and Shigella with blood and pus in the stool. A control series of children admitted with other complaints was also included, and the odds ratios for diarrhoea for the above five pathogens were 18.2, 9.6, 3.7, 2.2, and 1.6, respectively.
authors.affiliation: Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea.
authors.forename: P
authors.initials: P
authors.lastname: Howard
authors.forename: N D
authors.initials: ND
authors.lastname: Alexander
authors.forename: A
authors.initials: A
authors.lastname: Atkinson
authors.forename: A O
authors.initials: AO
authors.lastname: Clegg
authors.forename: G
authors.initials: G
authors.lastname: Gerega
authors.forename: A
authors.initials: A
authors.lastname: Javati
authors.forename: M
authors.initials: M
authors.lastname: Kajoi
authors.forename: S
authors.initials: S
authors.lastname: Lupiwa
authors.forename: T
authors.initials: T
authors.lastname: Lupiwa
authors.forename: M
authors.initials: M
authors.lastname: Mens
authors.forename: G
authors.initials: G
authors.lastname: Saleu
authors.forename: R C
authors.initials: RC
authors.lastname: Sanders
authors.forename: B
authors.initials: B
authors.lastname: West
authors.forename: M P
authors.initials: MP
authors.lastname: Alpers
mesh_terms: D001424:Bacterial Infections / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D016001:Confidence Intervals; D003906:Developing Countries; D003967:Diarrhea / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D005243:Feces / Q000382:microbiology / Q000469:parasitology / Q000821:virology; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007411:Intestinal Diseases, Parasitic / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D008297:Male; D009512:New Guinea / Q000453:epidemiology; D016017:Odds Ratio; D011379:Prognosis; D012424:Rural Population; D014777:Virus Diseases / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology