[Radiation hybrid mapping: statistical criteria and their properties].
Statistical tests specially developed for radiation hybrid (RH) mapping, modified likelihood-ratio test and Akaike's information content, are proposed. They allow several most likely gene orders to be identified to a certain accuracy. The properties of the proposed tests that characterize the accuracy of gene ordering as dependent on the number of genes mapped, the position of the selective gene, and the sample size have been studied. Recommendations as to the practical use of these tests are presented.
Svishcheva
G R
GR
Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russia.
Aksenovich
T I
TI
D004249:DNA Damage / Q000528:radiation effects*; D015233:Models, Statistical; D020161:Physical Chromosome Mapping / Q000379:methods*