Gene therapy for lung cancer.
The advances that have been made over the past decade in the field of gene transfer as well as in the fields of immunology and the molecular biology of tumorigenesis have brought to reality the possibility of using gene transfer as an anti-cancer treatment modality. The published results of clinical trials using this approach to date have been very limited, and a considerable amount of work still needs to be done in order to make this an effective treatment modality. However the developments that have occurred in the past several years indicate that this modality will become efficacious in the foreseeable future.
Antonia
S J
SJ
Clinical Investigations Program, H. Lee Moffitt Cancer Center, Tampa, Florida 33612, USA. antonias@moffitt.usf.edu
Sotomayor
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E
D017209:Apoptosis; D016147:Genes, Tumor Suppressor / Q000235:genetics*; D015316:Genetic Therapy; D006801:Humans; D007167:Immunotherapy; D008175:Lung Neoplasms / Q000235:genetics / Q000628:therapy*