T cells: A proliferation of costimulatory molecules.
The identification and characterization of a newly extended family of molecules related to the T-cell costimulatory proteins CD28 and B7 suggests that a distinct form of costimulatory signals could be important for effector T-cell responses outside of lymphoid tissues.
Mueller
D L
DL
Department of Medicine and Center for Immunology, University of Minnesota Medical School, Minneapolis 55455, USA. dmuell@mail.ahc.umn.edu
D000069594:Abatacept; D000595:Amino Acid Sequence; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000235:genetics / Q000276:immunology; D000945:Antigens, Differentiation, T-Lymphocyte / Q000235:genetics / Q000276:immunology*; D018122:B7-1 Antigen / Q000276:immunology*; D018106:CD28 Antigens / Q000235:genetics / Q000276:immunology*; D060908:CTLA-4 Antigen; D002455:Cell Division; D006801:Humans; D018796:Immunoconjugates; D007141:Immunoglobulin Fc Fragments / Q000235:genetics / Q000276:immunology; D060889:Inducible T-Cell Co-Stimulator Protein; D008024:Ligands; D008969:Molecular Sequence Data; D013601:T-Lymphocytes / Q000276:immunology*
D015703:Antigens, CD; D000943:Antigens, Differentiation; D000945:Antigens, Differentiation, T-Lymphocyte; D018122:B7-1 Antigen; D018106:CD28 Antigens; D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; C556692:ICOS protein, human; D018796:Immunoconjugates; D007141:Immunoglobulin Fc Fragments; D060889:Inducible T-Cell Co-Stimulator Protein; D008024:Ligands; D000069594:Abatacept