title: Neurobiology of posttraumatic stress disorder.
abstract: Recent advances on the neurobiology of posttraumatic stress disorder include: the utilization of functional brain imaging; the incorporation of cross-system research including neuroendocrine (hypothalamic-pituitary-adrenal and hypothalamic-pituitary-thyroid axes), neurochemical (corticotropin-releasing factor, norepinephrine, serotonin, endogenous opiates), and neuroimmunological (humoral and cellular immunity) systems; the expansion beyond exclusive study of combat veterans to include posttraumatic stress disorder patients suffering from noncombat traumas; and the development of animal models of traumatic stress.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Newport
authors.forename: C B
authors.initials: CB
authors.lastname: Nemeroff
mesh_terms: D000917:Antibody Formation; D001921:Brain / Q000473:pathology / Q000503:physiopathology; D003072:Cognition Disorders / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism; D007111:Immunity, Cellular; D008279:Magnetic Resonance Imaging; D018377:Neurotransmitter Agents / Q000378:metabolism; D010913:Pituitary-Adrenal System / Q000378:metabolism; D013313:Stress Disorders, Post-Traumatic / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D013961:Thyroid Gland / Q000378:metabolism
chemical_list: D018377:Neurotransmitter Agents