Case reports of nocardiosis in patients with human immunodeficiency virus (HIV) infection.
BACKGROUND
We present 4 local cases of nocardiosis in HIV-infected patients and discuss the diagnosis, clinical syndromes and therapy of nocardiosis.


METHODS
Two cases presented with pulmonary nocardiosis, one had a cervical lymph node abscess and one had disseminated nocardiosis with pulmonary, cerebral and soft tissue involvement.


METHODS
Combination therapy is often employed. Sulphonamides or co-trimoxazole, amikacin, imipenen, minocycline and ceftriaxone are some of the drugs that could be used.


RESULTS
Outcome hinges on the early recognition and optimal treatment of this infection.


CONCLUSIONS
Clinical presentations vary and diagnosis is difficult and frequently delayed. Nocardiosis should be suspected in patients who present with pulmonary lesions with soft tissue and/or cerebral abscesses.
Lee
C C
CC
Department of Infectious Disease, Tan Tock Seng Hospital, Singapore.
Loo
L W
LW
Lam
M S
MS
D000328:Adult; D001927:Brain Diseases / Q000382:microbiology*; D017809:Fatal Outcome; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008171:Lung Diseases / Q000382:microbiology*; D008297:Male; D009617:Nocardia Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D009616:Nocardia asteroides; D012874:Skin Diseases, Infectious / Q000382:microbiology*