Serum immunoglobulin type G concentrations in calves produced by IVF and delivered by elective cesarean section.
Colostrum ingestion by neonatal calves is widely recognized to provide passive transfer of immunity. In this study immunoglobulin absorption from colostrum was evaluated in 54 IVF-produced calves. The IVF calves were delivered by Cesarean section on Days 275 to 277 of gestation, 24 h after the dams had been administered 30 mg dexamethasone. The calves suckled bottles or were force-fed 6 L of colostrum in the first 12 h of life. Colostrum was obtained from the first post-calving milking of recipient dams or from frozen storage reserves if dam secretion was not adequate. Immunoglobulin type G (IgG) content of both sources of colostrum was determined. Serum samples from the calves were collected at 0, 12 and 24 h of age and analyzed for IgG. Twenty dairy calves born vaginally served as the controls and were subjected to the same colostrum management protocol except that the colostrum was obtained only from frozen post-calving milk of dairy cows from the same farm. The control calves were also subjected to the same sampling protocol. The IVF group of calves ingested more IgG (P < 0.0001) and absorbed more IgG by 24 h of age (P < 0.0001) than their control group counterparts. Absorption of IgG was analyzed by comparing the g/kg body weight of IgG with serum IgG values at corresponding times after birth. Colostrum absorption efficiency was the same for both IVF and control groups of calves at 12 and 24 h of age. There was a maximum IgG dose above which additional increases in serum IgG were not realized. The slightly premature, Cesarean delivered IVF calves absorbed IgG from colostrum similarly to control calves delivered vaginally.
Bailey
T L
TL
Department of Large Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech University, Blacksburg 24061, USA.
Whittier
W D
WD
Murphy
J M
JM
Schurig
G G
GG
Riva
A L
AL
Swecker
W S
WS
Pelzer
K D
KD
Bass
R T
RT
Caudell
D
D
Eyestone
W
W
D000818:Animals; D002417:Cattle / Q000276:immunology*; D002585:Cesarean Section / Q000662:veterinary*; D003126:Colostrum / Q000276:immunology; D005307:Fertilization in Vitro; D005865:Gestational Age; D007116:Immunization, Passive; D007074:Immunoglobulin G / Q000097:blood*
D007074:Immunoglobulin G