Posttraumatic akinetic-rigid syndrome resembling Parkinson's disease: a report on three patients.
We describe three patients who developed a rapidly evolving posttraumatic akinetic-rigid syndrome (ARS), the clinical manifestations of which were similar to Parkinson's disease, including response to levodopa. Despite initial imaging studies showing traumatic damage to the substantia nigra, the ARS appeared after a delay of 1-5 months after the injury. We stress the importance of magnetic resonance imaging to illustrate nigral damage in all patients in whom head trauma precedes an ARS.
Bhatt
M
M
Movement Disorders Clinic, Department of Neurology, Jaslok Hospital & Research Centre, Mumbai, India.
Desai
J
J
Mankodi
A
A
Elias
M
M
Wadia
N
N
D000328:Adult; D003937:Diagnosis, Differential; D004292:Dominance, Cerebral / Q000502:physiology; D016489:Head Injuries, Closed / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009127:Muscle Rigidity / Q000175:diagnosis*; D009460:Neurologic Examination; D010302:Parkinson Disease, Secondary / Q000175:diagnosis*; D013378:Substantia Nigra / Q000293:injuries* / Q000473:pathology