title: Hyperacuity deficits in anisometropic and strabismic amblyopes with known ages of onset.
abstract: In order to evaluate the influence of etiology of amblyopia and of age at onset of amblyopia on the resulting constellation of spatial vision deficits, resolution/vernier and recognition/resolution acuity ratios were measured in groups of children with either strabismic amblyopia or anisometropic amblyopia with known ages of onset. Strabismic amblyopia with infantile onset (<9 months) and strabismic amblyopia with late onset (18-30 months) were both associated with abnormally low resolution/vernier and abnormally high recognition/resolution acuity ratios. Among amblyopes with infantile onset (<9 months), moderate amblyopia was associated with different resolution/vernier and recognition/resolution acuity ratios in anisometropic and strabismic groups. Infantile amblyopes with poor acuity outcomes included children who initially presented with anisometropia but later developed strabismus and children who initially presented with esotropia but later developed anisometropia; both subgroups with mixed amblyopia had poor resolution/vernier acuity ratios. Data from moderate amblyopes support the hypothesis that anisometropia and strabismus disrupt visual maturation in fundamentally different ways rather than simply at different stages in visual development.
authors.affiliation: Retina Foundation of the Southwest, 9900 North Central Expressway, Suite 400, Dallas, TX 75231, USA. ebirch@retinafoundation.org
authors.forename: E E
authors.initials: EE
authors.lastname: Birch
authors.forename: W H
authors.initials: WH
authors.lastname: Swanson
mesh_terms: D017668:Age of Onset; D000550:Amblyopia / Q000503:physiopathology*; D002648:Child; D006801:Humans; D007223:Infant; D011446:Prospective Studies; D013285:Strabismus / Q000503:physiopathology*; D014792:Visual Acuity / Q000502:physiology*