title: Adenocarcinoma of the Endometrium: An Institutional Review.
abstract: BACKGROUND: Many oncologists regard endometrial cancer as a relatively benign and easily treatable gynecologic tumor. Inadequate care can result in poor outcomes. METHODS: The authors review the epidemiology and pathology of the disease, and they compare disease characteristics and outcomes of FIGO staging with their own 11-year experience at a tertiary referral center. RESULTS: Patients referred to tertiary referral centers tend to present with more advanced stages of disease than those reported by FIGO, although the profile of histologic types is similar. CONCLUSIONS: Prevention and early detection of endometrial cancer can minimize the impact of this disease. Complete staging and tumor removal including extrafascial hysterectomy with bilateral salpingo-oophorectomy, pelvic lymphadenectomy, and selective paraaortic lymphadenectomy are the cornerstones of surgical therapy.
authors.affiliation: Department of Obstetrics and Gynecology, University of South Florida College of Medicine, Tampa, Florida, 33606, USA.
authors.initials: D
authors.lastname: Cavanagh
authors.initials: JV
authors.lastname: Fiorica
authors.initials: MS
authors.lastname: Hoffman
authors.initials: J
authors.lastname: Durfee
authors.initials: SV
authors.lastname: Nicosia