title: Gastro-intestinal effects of Indian spice mixture (Garam Masala).
abstract: Spices are a part of diet all over the world but the variety and quantity consumed in tropical countries is particularly significant. The intestinal transit time of Indians is shorter, and their stool weight larger than that of Europeans on a comparable fibre intake. Ingestion of chilli is associated with a faster whole gut transit time. There is hardly any human work on the effects of spices on intestinal transit or gastric emptying. To explore the effects of spices on gastro intestinal transit this study was conducted on 18 well nourished healthy human adult volunteers using Radiolabelled Idli with or without Garam Masala. On gastric scintigraphy the gastric emptying time was much faster in subjects when spicy meal was given. The t1/2 of the spicy meal, 40.09 +/- (p < 0.05) thus implying a faster transit through the stomach. In 17 out of the 18 subjects t1/2 of the spicy meal was consistently lower than that of spicefree meal. The lag phase of gastric emptying showed no significant difference. There was a tendency towards slower gastrocolic transit with Spicefree meal but more subjects need to be done to confirm this.
authors.affiliation: All India Institute of Medical Sciences, New Delhi, India.
authors.forename: K P
authors.initials: KP
authors.lastname: Kochhar
authors.forename: R L
authors.initials: RL
authors.lastname: Bijlani
authors.forename: U
authors.initials: U
authors.lastname: Sachdeva
authors.forename: S C
authors.initials: SC
authors.lastname: Mahapatra
authors.forename: A K
authors.initials: AK
authors.lastname: Padhy
authors.forename: R K
authors.initials: RK
authors.lastname: Tandon
mesh_terms: D000328:Adult; D005746:Gastric Emptying / Q000502:physiology*; D005772:Gastrointestinal Transit / Q000502:physiology*; D006801:Humans; D012275:Oryza; D012016:Reference Values; D017365:Spices; D013667:Technetium
chemical_list: D013667:Technetium