[ANF--atrial natriuretic factor].
Is produced at the right atrium and is acting upon four types of receptors. The main effects of ANF are: renal effects, by rapid increasing and prolongation of glomerular filtration; neuroumoral effects--the inhibition of renin-angiotensin system and of the release of aldosterone; effects upon the vascular wall, with vasodilatation; another effect is the regulation of the hydrosalin balance. The therapeutical endpoints of ANF are related to its action in some diseases like: cardiac failure, arterial hypertension, myocardia infarction, paroxysmal arrhythmias; in some of them it is a very fiable predictive marker. ANF represents o neuroumoral mechanism which play an important role in functional regulation of the cardio-vascular system.
Mitu
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F
Clinica a VI-a Medicală, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
Dabija
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E
D000818:Animals; D009320:Atrial Natriuretic Factor / Q000737:chemistry / Q000494:pharmacology / Q000502:physiology* / Q000627:therapeutic use; D006801:Humans; D007668:Kidney / Q000502:physiology; D012084:Renin-Angiotensin System / Q000502:physiology; D014882:Water-Electrolyte Balance / Q000502:physiology
D009320:Atrial Natriuretic Factor