title: Spontaneous candida mediastinitis diagnosed by endoscopic ultrasound-guided, fine-needle aspiration.
abstract: Candida mediastinitis is a rare clinical entity associated with high mortality and morbidity. It is emerging as an important clinical entity, probably due to increased recognition of candida as a significant pathogen in mediastinitis. Candida mediastinitis is usually associated with cardiothoracic surgery, esophageal perforation, and head and neck infections. Optimal therapy for candida mediastinitis remains undefined. Aggressive, combined surgical debridement and antifungal therapy appears to be the most effective of available therapies. We report a case of spontaneous candida mediastinitis diagnosed by endoscopic ultrasound-guided, fine-needle aspiration and successfully treated with oral antifungal therapy alone.
authors.affiliation: Division of Gastroenterology, Scott & White Clinic and Memorial Hospital, Texas A&M University Health Science Center, College of Medicine, Temple 76508, USA.
authors.forename: V M
authors.initials: VM
authors.lastname: Prasad
authors.forename: R
authors.initials: R
authors.lastname: Erickson
authors.forename: E D
authors.initials: ED
authors.lastname: Contreras
authors.forename: F
authors.initials: F
authors.lastname: Panelli
mesh_terms: D001707:Biopsy, Needle / Q000295:instrumentation*; D002175:Candida / Q000648:ultrastructure; D002177:Candidiasis / Q000000981:diagnostic imaging / Q000473:pathology*; D003937:Diagnosis, Differential; D019160:Endosonography / Q000295:instrumentation*; D005260:Female; D006801:Humans; D008480:Mediastinitis / Q000000981:diagnostic imaging / Q000473:pathology*; D008482:Mediastinum / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology