title: Myoblast therapy for stress urinary incontinence and bladder dysfunction.
abstract: The field of tissue engineering and gene therapy has an exciting and promising future. During the past few years we have begun a comprehensive effort to investigate the use of myoblasts to improve and expand the treatment of stress urinary incontinence and bladder dysfunction. Moreover, we can expect the application of myoblast-mediated ex vivo gene transfer in the field of urology. In this paper we discuss the compositions of and methods involving the use of myogenic or muscle-derived cells for tissue engineering and cell-mediated gene therapy.
authors.affiliation: Division of Urologic Surgery, University of Pittsburgh School of Medicine, Pennsylvania, USA.
authors.forename: T
authors.initials: T
authors.lastname: Yokoyama
authors.forename: J
authors.initials: J
authors.lastname: Huard
authors.forename: M B
authors.initials: MB
authors.lastname: Chancellor
mesh_terms: D017690:Cell Transplantation; D006801:Humans; D009130:Muscle, Smooth / Q000166:cytology; D013997:Time Factors; D001745:Urinary Bladder Diseases / Q000628:therapy*; D014550:Urinary Incontinence, Stress / Q000628:therapy*