Use of a portable CT scanner during resection of subcortical supratentorial astrocytomas of childhood.
The development of intraoperative imaging has made it possible to visualize shifting brain structures during surgery, and may allow greater intraoperative discrimination of normal and abnormal tissue. This may provide greater confidence to the neurosurgeon to proceed with a more extensive resection while decreasing postoperative morbidity. We investigated the intraoperative use of a portable CT scanner in the resection of 4 cases of supratentorial, subcortical astrocytomas of childhood to assess its usefulness in determining the endpoint of the dissection. We operated on 4 patients, ages 3-17, with astrocytomas. Three were thalamic, and 1 was based primarily in the caudate nucleus. The approach to the basal ganglia was transcallosal in 3 and transtemporal in 1. Specific observations on the intraoperative use of the portable CT scanner included its overall facility, any additional operative time required, the overall quality of the images, intraoperative decisions made based on the images and problems associated with its use. These observations are presented with a review of intraoperative imaging as it pertains to deep pediatric brain tumors. The CT scanner was helpful in limiting the dissection of the hypothalamic and midbrain regions and in localizing remaining abnormal tissue. The scans allowed informed decisions about leaving margins of the tumor which were adjacent to vital structures, but dit not prove to be a decisive factor in providing a complete resection. The following observations are worth noting: (1) average imaging time was 20 min per scan; (2) the extent and location of residual enhancing tumor was easily identified despite other materials in the surgical bed; (3) air/tissue interfaces limit resolution; (4) tumors retain contrast long enough to obtain multiple scans without additional dye, and (5) the cost profile of a mobile CT scanner is superior to that of a fixed intraoperative CT scanner.
Gwinn
R
R
Department of Neurosurgery, Georgetown University Medical Center, Washington, DC 20007, USA.
Cleary
K
K
Medlock
M
M
D000293:Adolescent; D016477:Artifacts; D001254:Astrocytoma / Q000000981:diagnostic imaging* / Q000601:surgery*; D015982:Bias; D002648:Child; D002675:Child, Preschool; D003362:Cost-Benefit Analysis; D003657:Decision Making; D005260:Female; D006801:Humans; D008297:Male; D016343:Monitoring, Intraoperative / Q000191:economics / Q000379:methods*; D019095:Point-of-Care Systems / Q000191:economics; D015203:Reproducibility of Results; D015173:Supratentorial Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000191:economics / Q000379:methods*