title: Visceral manifestation of cat scratch disease in children. A consequence of altered immunological state?
abstract: A 12-year-old girl with a 2-month history of fever and abdominal pain was admitted to our hospital. Ultrasound and CT scans of the abdomen showed multiple hypoechoic lesions of liver and spleen. Screening for zoonosis revealed high positive titers to Bartonella henselae. T-cell deficiency was demonstrated and remained almost unchanged during a follow-up of 11 months. A review of the literature shows that disseminated visceral affection is a rare presentation of cat scratch disease (CSD) in childhood and adolescence. Further immunological investigations are needed in more patients with CSD to confirm whether an altered immunological state may be responsible for the atypical visceral manifestation of CSD.
authors.affiliation: University Children's Hospital, Dept. of Pediatrics, Karl Franzens University, Graz, Austria.
authors.forename: A
authors.initials: A
authors.lastname: Kahr
authors.forename: R
authors.initials: R
authors.lastname: Kerbl
authors.forename: K
authors.initials: K
authors.lastname: Gschwandtner
authors.forename: B
authors.initials: B
authors.lastname: Heinzl
authors.forename: H
authors.initials: H
authors.lastname: Lackner
authors.forename: W
authors.initials: W
authors.lastname: Schwinger
authors.forename: D
authors.initials: D
authors.lastname: Stünzner
authors.forename: F
authors.initials: F
authors.lastname: Lindbichler
authors.forename: E C
authors.initials: EC
authors.lastname: Urban
mesh_terms: D000818:Animals; D018416:Bartonella henselae / Q000302:isolation & purification*; D002372:Cat-Scratch Disease / Q000175:diagnosis*; D002648:Child; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008107:Liver Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013158:Splenic Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D015047:Zoonoses