[The comparative characteristics of the anti-inflammatory action of chorionic and placental extracts].
On the model of the caragenan-induced acute aseptic peritonitis in rats it was shown that in comparison with the extract of placenta the use of the chorion cryoextract leads to the faster completion of neutrophilic and higher stimulation of macrophagal and fibroblastic reaction in the inflammatory focus. Therefore, a new drug of the chorion cryoextract possesses stronger anti-inflammatory actions than the pharmacological preparation of placenta extract used in the same dose.
Klymenko
M O
MO
Kharkov Medical University, Ministry of Public Health of Ukraine.
Subota
N P
NP
Pit'ko
V A
VA
Tatarko
S V
SV
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002351:Carrageenan; D002823:Chorion / Q000737:chemistry*; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D008297:Male; D010538:Peritonitis / Q000139:chemically induced / Q000188:drug therapy; D010924:Placental Extracts / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014020:Tissue Extracts / Q000627:therapeutic use*
D000893:Anti-Inflammatory Agents; D010924:Placental Extracts; D014020:Tissue Extracts; D002351:Carrageenan