title: Gastric antral stricture in a patient with chronic granulomatous disease.
abstract: Chronic granulomatous disease (CGD) is a rare disorder of phagocytic cell oxidative metabolism. Patients have recurrent infections with catalase-positive organisms and granulomatous lesions throughout the body. Gastric antrum can be an occult site of involvement. We describe a four-year old boy with chronic granulomatous disease who was admitted with the complaints of persistent vomiting and weight loss. Gastric antral narrowing was diagnosed according to radiological findings. Treatment with steroid and antibiotics yielded a good clinical response in 15 days with a relief of the obstruction. This case report emphasizes the beneficial effect of this form of therapy in preventing life-threatening obstruction of vital organs in CGD.
authors.affiliation: Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara.
authors.forename: A
authors.initials: A
authors.lastname: Metin
authors.forename: O
authors.initials: O
authors.lastname: Sanal
authors.forename: I
authors.initials: I
authors.lastname: Tezcan
authors.forename: F
authors.initials: F
authors.lastname: Ersoy
authors.forename: A I
authors.initials: AI
authors.lastname: Berkel
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002374:Catalase / Q000378:metabolism; D002675:Child, Preschool; D005938:Glucocorticoids / Q000627:therapeutic use*; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D011707:Pyloric Stenosis / Q000188:drug therapy* / Q000209:etiology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D005938:Glucocorticoids; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D002374:Catalase; D008775:Methylprednisolone