title: [A retrospective clinical study on pneumococcal meningitis in 0- to 1-year-old infants hospitalized in 1987-1996 in the Infectious Disease Clinic, Iaşi].
abstract: During a period of ten years (1987-1996) in Iaşi Infections Diseases Hospital, were observed 19 children, 0-1 year, with pneumococcal meningitis. This disease represented one important cause of morbidity and mortality in children in developing countries. Clinical symptoms in these cases were very serious, including: fever, headache, vomiting, altered sensorium, seizures etc. Cerebrospinal fluid analysis confirmed the diagnosis, after showing purulent, turbid fluid. The germ was isolated in 100% of the cases through direct examination and culture of cerebrospinal fluid. They were treated with penicillin and chloramphenicol (55%) and ampicillin and chloramphenicol. The mortality was 52%. This study concludes that delay in diagnosis, virulence of germ, prematurity and hypertrophy were elements of a bad prognosis.
authors.affiliation: Clinica de Boli Infecţioase, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
authors.forename: E
authors.initials: E
authors.lastname: Rudnic
mesh_terms: D000900:Anti-Bacterial Agents; D003141:Communicable Diseases; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D006760:Hospitalization / Q000706:statistics & numerical data; D006782:Hospitals, Special; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008586:Meningitis, Pneumococcal / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D012189:Retrospective Studies; D012383:Romania / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents