title: Antagonistic behavior, dominance, hostility, and coronary heart disease.
abstract: OBJECTIVE
  This study investigated the relationship between antagonistic behavior, dominance, attitudinal hostility, and coronary heart disease (CHD).
  
  
  METHODS
  One hundred one men and 95 women referred for thallium stress testing were administered the Structured Interview and the Cook-Medley Hostility Scale. The Hostile Behavior Index, derived from the Structured Interview and developed by Haney et al., served as an index of antagonism, and the frequency with which interviewees interrupted their interviewer served as a measure of dominance. On the basis of their medical history and thallium stress test results, patients were classified as having (N = 44) or not having (N = 99) CHD.
  
  
  CONCLUSIONS
  Multivariate logistic regressions (with age, gender, disease, and lifestyle risk factors in the model) revealed that both the Hostile Behavior Index and dominance were significant independent risk factors for CHD (relative risk [RR] = 1.22 and 1.47, p < .03). Of the two Hostile Behavior Index component scores, indirect challenge and irritability, only the latter correlated significantly with CHD (RR = 1.27, p < .03). Separate logistic regressions for men and women suggest that subtle, indirect manifestations of antagonism confer CHD risk in women and that more overt expressions of anger confer risk in men. A significant univariate correlation between hostility scale scores and CHD became not significant when we adjusted for socioeconomic status.
authors.affiliation: Department of Psychology, University of Maryland, Baltimore 21250, USA.
authors.forename: A W
authors.initials: AW
authors.lastname: Siegman
authors.forename: S T
authors.initials: ST
authors.lastname: Townsend
authors.forename: A C
authors.initials: AC
authors.lastname: Civelek
authors.forename: R S
authors.initials: RS
authors.lastname: Blumenthal
mesh_terms: D000368:Aged; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000523:psychology*; D005080:Exercise Test; D005260:Female; D006791:Hostility; D006801:Humans; D016015:Logistic Models; D008297:Male; D008396:Maryland; D008875:Middle Aged; D011159:Population Surveillance; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D012494:Sampling Studies; D012737:Sex Factors; D012930:Social Dominance; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D013794:Thallium Radioisotopes