Beta-secretase revealed: starting gate for race to novel therapies for Alzheimer's disease.
Skovronsky
D M
DM
Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Maloney 3, HUP, Philadelphia, PA 19104-4283, USA. skodanm@mail.med.upenn.edu
Lee
V M
VM
D000544:Alzheimer Disease / Q000188:drug therapy*; D053829:Amyloid Precursor Protein Secretases; D016282:Aspartic Acid Endopeptidases / Q000235:genetics* / Q000502:physiology; D015415:Biomarkers; D010450:Endopeptidases; D006801:Humans
D015415:Biomarkers; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; D016282:Aspartic Acid Endopeptidases; C509284:BACE2 protein, human; C509280:BACE1 protein, human