Gene expression analysis.
The response of cells to extracellular signals usually requires altered expression of many genes, possibly including several distinct metabolic pathways. In some cases, only a subset of genes involved in such responses are known, which requires techniques to analyze changes in the expression of multiple genes, both known and unknown. Three techniques, two-dimensional gel electrophoresis, differential display, and gene discovery arrays, provide opportunities for measuring changes in gene expression levels, as well as for identifying novel gene products.
Oetting
W S
WS
Department of Medicine, University of Minnesota, Minneapolis 55455, USA. bill@lenti.med.umn.edu
D000818:Animals; D015870:Gene Expression; D008967:Molecular Biology / Q000379:methods*; D015398:Signal Transduction / Q000235:genetics*