title: [Use of the anesthetic cream EMLA in arterial punction].
abstract: BACKGROUND
  Arterial puncture is a painful procedure requiring prior local anesthesia. Various products are available for pain relief, among them EMLA anesthetic cream.
  
  
  OBJECTIVE
  To compare pain from simple puncture of the radial artery performed with or without application of EMLA anesthetic cream and after infiltration of mepivacaine.
  
  
  METHODS
  A prospective, random double-blind study of 153 patients in three groups: group A, 51 patients who were applied 1 g of EMLA cream; group B, 52 patients who were applied 1 g of placebo cream; and group C, 50 patients who received infiltration of 0.2 ml of 1% mepivacaine. Pain was assessed on a 10 cm visual analog scale (0, absence of pain; 10, greatest imaginable pain).
  
  
  RESULTS
  Pain intensity reported by the patients was 2.6 +/- 1.8 in group A, 2.9 +/- 1.8 in group B and 1.6 +/- 1.8 in group C. The results for group C were statistically different from those for groups A and B. The difference between groups A (EMLA) and B (placebo), however, was not statistically significant.
  
  
  CONCLUSIONS
  Mepivacaine infiltration is the more effective method for minimizing pain from puncture of the radial artery. EMLA anesthetic cream is not effective against pain caused by this procedure.
authors.affiliation: Departament de Pneumologia, Hospital de la Santa Creu i Sant Pau, Facultad de Medicina UAB Barcelona.
authors.forename: J
authors.initials: J
authors.lastname: Giner
authors.forename: P
authors.initials: P
authors.lastname: Casan
authors.forename: J
authors.initials: J
authors.lastname: Belda
authors.forename: H
authors.initials: H
authors.lastname: Litvan
authors.forename: J
authors.initials: J
authors.lastname: Sanchis
mesh_terms: D000772:Anesthesia, Local; D000779:Anesthetics, Local; D001158:Arteries; D001800:Blood Specimen Collection / Q000009:adverse effects*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008012:Lidocaine; D000077442:Lidocaine, Prilocaine Drug Combination; D008297:Male; D008875:Middle Aged; D009824:Ointments; D010146:Pain / Q000209:etiology / Q000517:prevention & control*; D011318:Prilocaine; D011446:Prospective Studies
chemical_list: D000779:Anesthetics, Local; D000077442:Lidocaine, Prilocaine Drug Combination; D009824:Ointments; D011318:Prilocaine; D008012:Lidocaine