White blood cells 1: non-malignant disorders.
Disorders of white cells are very common in clinical practice. White-cell development and numbers are controlled by a mixture of external stimuli including cytokines, matrix proteins, and accessory cells. Several different white-cell lineages are recognised; each has a role in host defence. Both white-cell deficiency and overproduction can lead to disease. Some forms of inherited white-cell deficiency are potentially treatable with gene therapy.
Stock
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Department of Medicine, University of Illinois at Chicago School of Medicine, USA.
Hoffman
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D016207:Cytokines / Q000502:physiology; D003937:Diagnosis, Differential; D015316:Genetic Therapy; D006801:Humans; D007958:Leukocyte Count; D007960:Leukocyte Disorders / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology
D016207:Cytokines