[Autoimmune disorders in liqvidators 11 years after the Chernobyl accident].
We studied long-lasting consequences of the low-doses irradiation on the immune system of 71 clean-up workers who participated in the emergency work after the Chernobyl Plant accident in 1986 and 25 healthy donors from Belarus. In sera of the workers the level of autoantibodies to thyroid gland antigens (thyroglobulin and microsomal fraction of thyroid gland) was increased in 48% of cases, the level of autoantibodies to lens oculis antigen was increased in 44% of cases; the level of circulating immune complexes was elevated in 55%, and the serum level of thyroglobulin in 60% of people. Immunological disorders were found without any definite clinical evidences of diseases and this allows us to consider the examined contingent as a group of risk for the development of autoimmune pathology in the future.
Kiseleva
E P
EP
Institute for Experimental Medicine RAMN, St. Petersburg, Russia. Aleksei.Kiselev@pobox.spbu.ru
Kositskaia
L S
LS
Freĭdlin
I S
IS
Rudenko
I Ia
IIa
Kuz'menok
O I
OI
Potapnev
M P
MP
D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D001324:Autoantigens / Q000276:immunology; D001327:Autoimmune Diseases / Q000097:blood / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011210:Power Plants; D011832:Radiation Injuries / Q000276:immunology*; D018788:Radioactive Hazard Release; D013997:Time Factors; D014455:Ukraine
D001323:Autoantibodies; D001324:Autoantigens