Chlorination of nucleobases, RNA and DNA by myeloperoxidase: a pathway for cytotoxicity and mutagenesis by activated phagocytes.
Henderson
J P
JP
Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Byun
J
J
Heinecke
J W
JW
D003602:Cytotoxicity, Immunologic; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000096:biosynthesis / Q000378:metabolism; D006801:Humans; D016296:Mutagenesis; D009195:Peroxidase / Q000378:metabolism*; D010586:Phagocytes / Q000378:metabolism*
D003841:Deoxycytidine; C035826:5-chloro-2'-deoxycytidine; D009195:Peroxidase