title: [Septic conditions: a syndrome of multiorgan dysfunction].
abstract: Using a new concept of terminology for sepsis syndrome, septic shock and multiorgan dysfunction/failure syndrome (MODS/MOSF) as a framework, we have evaluated 21 cases of severe sepsis of new admitted newborns in Neonatology Department of Pediatric clinic of Clinical center University of Sarajevo during last 2 years. We found that the most common etiologic agents were gram negative organisms (Klebsiella pn. and E. coli) and staphylococci. We did not observed any streptococcus group B sepsis despite of high incidence of these infections in developed countries. In 12 (60%) of 21 patients with severe sepsis MODS was developed, involving at least two organ systems, 3 of them also had the other acute insult (emergency surgery and asphyxia) as a possible trigger for MODS. The incidence of specific organ failure was: CNS (58%), respiratory (50%), cardiovascular (41%), the other systems were less involved. The overall mortality rate of patients with sepsis was 28%, whereas the overall mortality rate of MODS/MOSF was 50%.
authors.affiliation: Pedijatrijska klinika, Klinicki centar Univerziteta u Sarajevu.
authors.forename: S
authors.initials: S
authors.lastname: Heljić
authors.forename: I
authors.initials: I
authors.lastname: Kalkan
authors.forename: H
authors.initials: H
authors.lastname: Maksić
authors.forename: A
authors.initials: A
authors.lastname: Dzinović
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D018746:Systemic Inflammatory Response Syndrome / Q000175:diagnosis / Q000209:etiology / Q000628:therapy