title: Ultrasound-guided core needle biopsy for breast cancer: preliminary report.
abstract: BACKGROUND
  Ultrasound-guided automated percutaneous core needle biopsy (US-CNB) for breast tumors has been introduced into clinical practice, but it has not yet been used routinely. We evaluated its usefulness, especially in terms of histological accuracy.
  
  
  METHODS
  Thirty-one consecutive patients underwent mammography followed by breast biopsy with the automated core needle biopsy device.
  
  
  RESULTS
  Mammography was highly suggestive of malignancy or suspicious abnormalities in 17 cases whose histological findings from US-CNB specimens were invasive ductal carcinoma without exception. The other 14 cases with benign or probably benign mammography findings showed no malignancy histologically in the US-CNB specimens. In cases of malignancy, the accuracy rates of histological findings for the specimens obtained by US-CNB were 94.1% in histological type, 100% in direct infiltration, 82.4% in lymphatic infiltration, 82.4% in venous infiltration, 94.1% in histological grading and 82.4% in intraductal spread.
  
  
  CONCLUSIONS
  US-CNB was useful for making reliable preoperative histopathological diagnosis and may substitute fine needle aspiration biopsy and surgical biopsy.
authors.affiliation: Second Department of Surgery, Tokyo Medical and Dental University, School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Osanai
authors.forename: N
authors.initials: N
authors.lastname: Gomi
authors.forename: T
authors.initials: T
authors.lastname: Wakita
authors.forename: T
authors.initials: T
authors.lastname: Yamashita
authors.forename: W
authors.initials: W
authors.lastname: Ichikawa
authors.forename: Z
authors.initials: Z
authors.lastname: Nihei
authors.forename: K
authors.initials: K
authors.lastname: Sugihara
mesh_terms: D001706:Biopsy / Q000379:methods; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D009367:Neoplasm Staging / Q000379:methods; D012680:Sensitivity and Specificity; D018084:Ultrasonography, Interventional / Q000379:methods*