title: [A case with infectious mononucleosis-like syndrome caused by human herpes virus-6 infection].
abstract: A 26-year-old female was admitted because of multiple fractures in lower extremities. While in the hospital, she developed a high fever and generalized skin eruption. Physical examination revealed bilateral cervical lymphadenopathy and mild hepatosplenomegaly. The white cell count was 11,200 with 11% atypical lymphocytes. Serum GOT, GPT, LDH were markedly elevated. Infectious mononucleosis was suspected, but the serological test for EB virus did not show evidence of acute EB virus infection. Anti-HSV, CMV, hepatitis A virus antibody titers also did not show significant change during the coarse. The serological test for HHV-6 only showed increased titer of IgM and IgG antibodies. Rapidly elevated IgG antibody titer was indicative of reactivation of HHV-6. So, she was diagnosed as mononucleosis-like syndrome caused by HHV-6, probably reactivated infection. Her symptoms gradually disappeared during a month.
authors.affiliation: Department of Medicine, Kawasaki Medical School Kawasaki Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Karino
authors.forename: N
authors.initials: N
authors.lastname: Asaoka
authors.forename: T
authors.initials: T
authors.lastname: Sunagawa
authors.forename: H
authors.initials: H
authors.lastname: Ohba
authors.forename: H
authors.initials: H
authors.lastname: Yoneyama
authors.forename: Y
authors.initials: Y
authors.lastname: Kobashi
authors.forename: J
authors.initials: J
authors.lastname: Okimoto
authors.forename: R
authors.initials: R
authors.lastname: Soejima
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006566:Herpesviridae Infections / Q000175:diagnosis*; D015654:Herpesvirus 6, Human; D006801:Humans; D007244:Infectious Mononucleosis / Q000175:diagnosis*