Sclerosing encapsulating peritonitis in pediatric peritoneal dialysis patients.
The aim of this study was to define the incidence and characteristics of sclerosing encapsulating peritonitis (SEP) in pediatric peritoneal dialysis (PD) patients in Japan. A questionnaire was sent to all dialysis units with at least two pediatric PD patients. Among 687 patients registered, 11 cases (1.6%) of SEP were diagnosed. The mean age of patients with SEP at the start of PD was 9.7+/-3.6 years and at SEP diagnosis, 19.1+/-3.8 years. All patients had undergone PD for more than 5 years, and the mean PD duration was 9.6+/-3.3 years. SEP was diagnosed in 6.6% and 12% of patients dialyzed for >5 years and >8 years, respectively. The incidence of peritonitis among patients with SEP was not different from that among the Japanese pediatric registry. All patients had virtually no residual urine volume and 9 had impaired peritoneal ultrafiltration. Peritoneal calcification was the most-frequent radiological finding. Peritoneal biopsy was performed in 7 patients and confirmed sclerotic peritonitis in all. Ten patients transferred to hemodialysis, and only 1 patient underwent surgery. Three patients died. We recommend that patients on PD for more than 5 years who have impaired peritoneal ultrafiltration or peritoneal calcification should be carefully managed as presumptive cases of SEP.
Hoshii
S
S
Department of Pediatrics, Nishi-Sapporo National Hospital, Hokkaido, Japan. shoshii@pa2.so-net.ne.jp
Honda
M
M
Itami
N
N
Oh
S
S
Matsumura
C
C
Moriya
S
S
Mori
M
M
Hatae
K
K
Ito
Y
Y
Karashima
S
S
D000293:Adolescent; D000328:Adult; D002177:Candidiasis; D016983:Enterococcus; D016908:Gram-Positive Bacterial Infections; D006801:Humans; D009026:Mortality; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010537:Peritoneum / Q000473:pathology; D010538:Peritonitis / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology / Q000473:pathology*; D012598:Sclerosis; D013203:Staphylococcal Infections