title: Prevalence of osteoporosis risk factors and treatment among women aged 50 years and older.
abstract: We conducted a cross-sectional, retrospective review to evaluate screening, diagnosis, and treatment of 389 women aged 50 years or older at risk for osteoporosis in a large primary care practice. Records randomly selected from a computerized database were reviewed for drug history, age, height, weight, and osteoporosis-related diagnoses, symptoms, and risk factors. Among the 389 women, 255 (65.5%) were receiving bone-preserving treatment (247 estrogen replacement exclusively). Most (70.4%) were white, with an average age of 61 years, and an average of 3.3 risk factors for osteoporosis. Risk factors were postmenopausal status 94%, age 65 years or older 53%, hysterectomy 39%, cigarette smoking 33%, and physical inactivity 30%. By logistic regression, the only positive predictor of antiresorptive therapy was hysterectomy (adjusted odds ratio [AOR] 2.52, 95% confidence interval [CI] 1.54-4.14). Negative predictors were physical inactivity (AOR 0.44, 95% CI 0.25-0.71), rheumatoid arthritis (AOR 0.31, 95% CI 0.12-0.79), and age 65 years and older (AOR 0.54, 95% CI 0.34-0.86). Controlling for age, women with four or more risk factors were 62% less likely to be receiving antiresorptive treatment (AOR 0.38, 95% CI 0.23-0.64) than those with fewer risk factors.
authors.affiliation: Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1084, USA.
authors.forename: J K
authors.initials: JK
authors.lastname: Kirk
authors.forename: J G
authors.initials: JG
authors.lastname: Spangler
authors.forename: F S
authors.initials: FS
authors.lastname: Celestino
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid; D003430:Cross-Sectional Studies; D004358:Drug Therapy / Q000706:statistics & numerical data; D015914:Estrogen Replacement Therapy / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007044:Hysterectomy; D016015:Logistic Models; D008875:Middle Aged; D010024:Osteoporosis / Q000453:epidemiology / Q000517:prevention & control / Q000628:therapy*; D010809:Physical Fitness; D017698:Postmenopause; D015995:Prevalence; D011897:Random Allocation; D012189:Retrospective Studies; D012307:Risk Factors; D012907:Smoking