[Evaluation of a new amino acid mixture for the treatment of phenylketonuria].
BACKGROUND
To assess the acceptability and nutritional adequacy of a new phenylalanine-free amino acid mixture (Phenylade-Dietetic Metabolic Food).


METHODS
Twenty PKU patients (aged 2.6-10 years) diagnosed and followed by our Department. The children were given this product for a minimum of 4 and a maximum of 12 months. The clinical control has been carried out before treatment and then every 3 months. The biochemical parameters included: quantitative plasma amino acids, hematologic measurements of nutritional adequacy folic acid and vitamin B12.


RESULTS
All patients (except one) found this new product to be an acceptable alternatives as to taste and convenience to the previous low phenylalanine protein substitutes.


CONCLUSIONS
Normal growth was maintained.
Cerone
R
R
Dipartimento di Pediatria, Istituto G. Gaslini, Genova.
Barella
C
C
Fantasia
A R
AR
Schiaffino
M C
MC
D000596:Amino Acids / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010649:Phenylalanine / Q000378:metabolism; D010661:Phenylketonurias / Q000178:diet therapy*
D000596:Amino Acids; D010649:Phenylalanine