title: Nerve distribution to the human knee joint: anatomical and immunohistochemical study.
abstract: The nerve distribution to the knee joints was analyzed in 5 cadavers and 10 joint capsules specimens were resected during total knee arthroplasty. We found nerve fibers immunoreactive for anti-substance P antibody in the articular capsule. By confocal laser scanning microscopy, we evaluated the three-dimensional structures of the Ruffini's corpuscles and the free nerve endings, both of which were immunoreactive for anti-protein gene product 9.5.
authors.affiliation: Department of Orthopaedic Surgery, Kyoto Prefectural University of Medicine, Kyoto City, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Hirasawa
authors.forename: S
authors.initials: S
authors.lastname: Okajima
authors.forename: M
authors.initials: M
authors.lastname: Ohta
authors.forename: T
authors.initials: T
authors.lastname: Tokioka
mesh_terms: D019645:Arthroplasty, Replacement, Knee; D002102:Cadaver; D006652:Histological Techniques; D006801:Humans; D007150:Immunohistochemistry; D007719:Knee Joint / Q000033:anatomy & histology / Q000294:innervation*; D018613:Microscopy, Confocal; D008875:Middle Aged; D013373:Substance P / Q000032:analysis; D013869:Thiolester Hydrolases / Q000032:analysis; D043222:Ubiquitin Thiolesterase
chemical_list: D013373:Substance P; D013869:Thiolester Hydrolases; D043222:Ubiquitin Thiolesterase