title: White blood cells 1: non-malignant disorders.
abstract: Disorders of white cells are very common in clinical practice. White-cell development and numbers are controlled by a mixture of external stimuli including cytokines, matrix proteins, and accessory cells. Several different white-cell lineages are recognised; each has a role in host defence. Both white-cell deficiency and overproduction can lead to disease. Some forms of inherited white-cell deficiency are potentially treatable with gene therapy.
authors.affiliation: Department of Medicine, University of Illinois at Chicago School of Medicine, USA.
authors.forename: W
authors.initials: W
authors.lastname: Stock
authors.forename: R
authors.initials: R
authors.lastname: Hoffman
mesh_terms: D016207:Cytokines / Q000502:physiology; D003937:Diagnosis, Differential; D015316:Genetic Therapy; D006801:Humans; D007958:Leukocyte Count; D007960:Leukocyte Disorders / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology
chemical_list: D016207:Cytokines