Behavioral test systems in marmoset monkeys.
A number of neurobehavioral methods have been developed to test behavior in marmoset monkeys. These test systems are (1) the bungalow test, which quantifies spontaneous explorative behavior, (2) the hand-eye coordination test, which tests a learned task of coordinated motor behavior, and (3) the fear-potentiated startle response, which tests and quantifies pathological anxiety manifested by a response of fright. The test systems are extensively discussed, and the value of these test systems is exemplified by applying them to neurological disorders to register disease activity and drug efficacy.
Philippens
I H
IH
Department of Pharmacology, TNO Pharma, Rijswijk, The Netherlands. philippens@pml.tno.nl
Melchers
B P
BP
Roeling
T A
TA
Bruijnzeel
P L
PL
D000818:Animals; D001007:Anxiety / Q000175:diagnosis; D001522:Behavior, Animal / Q000502:physiology*; D001927:Brain Diseases / Q000175:diagnosis; D002144:Callithrix; D005133:Eye Movements / Q000502:physiology; D006801:Humans; D011581:Psychological Tests; D013216:Reflex, Startle / Q000502:physiology