Fluconazole-induced agranulocytosis with eosinophilia.
Fluconazole is a commonly prescribed antifungal agent with a favorable safety profile. A patient experienced agranulocytosis and eosinophilia associated with the drug. Similar bone marrow-suppressive effect due to the azoles is rarely described in the English-language literature.
Wong-Beringer
A
A
College of Pharmacy, Western University of Health Sciences, Pomona, California 91766-1889, USA.
Shriner
K
K
D000368:Aged; D000380:Agranulocytosis / Q000139:chemically induced*; D000935:Antifungal Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004802:Eosinophilia / Q000139:chemically induced*; D015725:Fluconazole / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D016919:Meningitis, Cryptococcal / Q000188:drug therapy
D000935:Antifungal Agents; D015725:Fluconazole