title: Cardiac arrest and the role of thrombolytic agents.
abstract: Thrombolytic agents may have clinically significant beneficial effects in cardiac arrest. The application of thrombolytic drugs in the setting of current and antecedent cardiopulmonary resuscitation is well documented; however, it has not been systematically studied nor has it been widely considered. We provide a literature review of thrombolytic agents and cardiopulmonary resuscitation to discuss the need for randomized controlled trials and the possibility of benefits in acute resuscitation.
authors.affiliation: University of Pittsburgh Medical Center, Pittsburgh, PA, USA. Newman44@pol.net
authors.forename: D H
authors.initials: DH
authors.lastname: Newman
authors.forename: I
authors.initials: I
authors.lastname: Greenwald
authors.forename: C W
authors.initials: CW
authors.lastname: Callaway
mesh_terms: D016887:Cardiopulmonary Resuscitation; D003131:Combined Modality Therapy; D005343:Fibrinolytic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D006323:Heart Arrest / Q000188:drug therapy* / Q000401:mortality; D006801:Humans; D015996:Survival Rate; D015912:Thrombolytic Therapy; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents