title: Retinoblastoma protein in microphthalmic mice.
abstract: A microphthalmic strain of mice was used to study immunoresponse of the retinoblastoma protein. Comparing wild-type, heterozygote and homozygote microphthalmic eyes, we found an increasing labelling of phosphorylated retinoblastoma protein (pRb) in the retinal pigment epithelium. Additionally, microphthalmic eyes expressed pRb in the neuroepithelium. Especially rosettes were strongly labelled.
authors.affiliation: Institute of Anatomy, University of Leipzig, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Richter
authors.forename: E
authors.initials: E
authors.lastname: Brylla
authors.forename: C
authors.initials: C
authors.lastname: Lenk
authors.forename: J
authors.initials: J
authors.lastname: Ernstberger
authors.forename: H
authors.initials: H
authors.lastname: Hilbig
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D051379:Mice; D008850:Microphthalmos / Q000276:immunology / Q000473:pathology*; D012160:Retina / Q000737:chemistry; D019572:Retinal Neoplasms / Q000276:immunology / Q000473:pathology*; D012175:Retinoblastoma / Q000276:immunology / Q000473:pathology*; D016160:Retinoblastoma Protein / Q000096:biosynthesis / Q000276:immunology* / Q000494:pharmacology
chemical_list: D016160:Retinoblastoma Protein