title: Intraarticular glucocorticosteroid injection into the lateral atlantoaxial joint under fluoroscopic control. A retrospective comparative study in patients with mechanical and inflammatory disorders.
abstract: OBJECTIVE
  To evaluate the overall efficacy in various disorders of glucocorticoid injection into the lateral atlantoaxial joints, performed via the posterior route under fluoroscopic control.
  
  
  METHODS
  Retrospective study of 26 patients including 16 (19 injections) with mechanical disorders and ten (16 injections) with inflammatory disorders.
  
  
  RESULTS
  The response rate was 69.3%, the mean pain scale score decrease was 52.3 +/- 40.1%, and the mean duration of pain relief was 8.1 +/- 11.8 months. All three parameters were significantly (P < 0.005) better in the subgroup with inflammatory disorders than in the subgroup with mechanical disorders (response rate, 100% vs 50%; pain scale score decrease, 80 +/- 27% vs 34.2 +/- 40%, and pain relief duration, 16.9 +/- 14.9 months vs 24.5 months). A single patient developed a side effect (moderately severe hypertension).
  
  
  CONCLUSIONS
  Glucocorticoid injection into the lateral atlantoaxial joints is a valid treatment alternative in patients who fail to respond to conventional noninvasive therapy.
authors.affiliation: Rheumatology Department, Hôtel-Dieu Teaching Hospital, Nantes, France.
authors.forename: J
authors.initials: J
authors.lastname: Glémarec
authors.forename: P
authors.initials: P
authors.lastname: Guillot
authors.forename: Y
authors.initials: Y
authors.lastname: Laborie
authors.forename: J M
authors.initials: JM
authors.lastname: Berthelot
authors.forename: A
authors.initials: A
authors.lastname: Prost
authors.forename: Y
authors.initials: Y
authors.lastname: Maugars
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000503:physiopathology; D001268:Atlanto-Axial Joint / Q000187:drug effects* / Q000293:injuries; D005260:Female; D005471:Fluoroscopy; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007270:Injections, Intra-Articular; D008297:Male; D008875:Middle Aged; D019838:Neck Injuries / Q000188:drug therapy / Q000503:physiopathology; D010003:Osteoarthritis / Q000188:drug therapy* / Q000503:physiopathology; D010147:Pain Measurement / Q000187:drug effects; D012189:Retrospective Studies; D013167:Spondylitis, Ankylosing / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids