title: A report of a rare chromosome 9 variant with an unusual G-banding pattern in the 9qh region.
abstract: We present a case of a Caucasian multigravida with advanced maternal age who showed evidence of an unusual heterochromatin banding pattern on chromosome 9 and a similar fetal karyotype on amniocentesis. Although unusual banding patterns of this region have been described earlier, we report a new, clinically insignificant pattern. This case illustrates the care needed in analysing the heterochromatin region for accurate clinical interpretation of chromosome 9 polymorphisms.
authors.affiliation: Department of Pediatrics, Texas Tech University Health Sciences Center, Lubbock, USA.
authors.forename: V
authors.initials: V
authors.lastname: Tonk
authors.forename: J
authors.initials: J
authors.lastname: Krishna
mesh_terms: D000328:Adult; D000649:Amniocentesis; D000653:Amniotic Fluid / Q000166:cytology*; D002899:Chromosomes, Human, Pair 9 / Q000235:genetics*; D005260:Female; D014644:Genetic Variation; D006570:Heterochromatin / Q000235:genetics*; D006801:Humans; D008423:Maternal Age; D011110:Polymorphism, Genetic / Q000235:genetics*; D011247:Pregnancy; D012680:Sensitivity and Specificity
chemical_list: D006570:Heterochromatin