title: Parasitic lesion of the insula suggesting cerebral sparganosis: case report.
abstract: Cerebral sparganosis, a parasitic disease, rarely produces a chronic active inflammatory response in the brain. Clinically and radiographically the process may mimic a neoplasm. We report a 30-year-old man who underwent surgical exploration for a mass in the insular cortex. Histology revealed a densely fibrotic mass heavily infiltrated with plasma cells and lymphocytes, in which were embedded parasitic forms consistent with sparganosis. We describe the MRI appearances and pathologic features. Intracranial mass lesions secondary to sparganosis must be considered in patients with a history of travel to endemic areas, especially Asia.
authors.affiliation: Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.
authors.forename: T J
authors.initials: TJ
authors.lastname: Cummings
authors.forename: J F
authors.initials: JF
authors.lastname: Madden
authors.forename: L
authors.initials: L
authors.lastname: Gray
authors.forename: A H
authors.initials: AH
authors.lastname: Friedman
authors.forename: R E
authors.initials: RE
authors.lastname: McLendon
mesh_terms: D000328:Adult; D000818:Animals; D001921:Brain / Q000469:parasitology / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis; D020807:Central Nervous System Parasitic Infections / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013031:Sparganosis / Q000175:diagnosis* / Q000473:pathology; D013146:Spirometra