Siamenol, a new carbazole alkaloid from Murraya siamensis.
A new carbazole alkaloid, siamenol (1), and two known alkaloids, mahanimbine (2) and mahanimbilol (3), have been isolated from the organic extract of Murraya siamensis. The novel compound exhibited HIV-inhibitory activity.
Meragelman
K M
KM
Laboratory of Drug Discovery Research and Development, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, NCI-FCRDC, Frederick, Maryland 21702, USA.
McKee
T C
TC
Boyd
M R
MR
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019380:Anti-HIV Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002227:Carbazoles / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D013057:Spectrum Analysis
D000470:Alkaloids; D019380:Anti-HIV Agents; D002227:Carbazoles; C408013:siamenol