title: Thoracic wall lipoblastoma: a case report and review of histopathology and cytogenetics.
abstract: A rare case of a successfully excised intra- and extrathoracic lipoblastoma of the anterior chest wall in a 13-month-old female infant is reported. Histopathology and cytogenetical analysis established the diagnosis of a lipoblastoma. The differential diagnosis, histology and cytogenetical evaluation of lipomatous neoplasms are discussed. Karyotypic analysis may be of use in diagnostically difficult cases owing to the characteristic alterations in 18q11-13. A complete resection of lipoblastomas is feasible and advantageous with no need for a mutilating radical excision.
authors.affiliation: Wessex Regional Centre for Pediatric Surgery, Southampton University Hospitals NHS Trust, UK.
authors.forename: M
authors.initials: M
authors.lastname: Samuel
authors.forename: I E
authors.initials: IE
authors.lastname: Moore
authors.forename: D M
authors.initials: DM
authors.lastname: Burge
mesh_terms: D020732:Cytogenetic Analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D008067:Lipoma / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D011859:Radiography; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D013899:Thoracic Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology* / Q000601:surgery