[Pulmonary hemorrhage with respiratory insufficiency in Henoch- Schoenlein purpura].
A 20-year-old woman presented with abdominal pain, purpura on the extremities, and arthralgia. The diagnosis of Henoch-Schönlein purpura was made based on granular IgA deposits in the vessels in a skin biopsy. Three weeks after onset of these symptoms, she developed glomerulonephritis and diffuse alveolar haemorrhage; she developed respiratory failure and needed mechanical ventilation. She recovered upon treatment with corticosteroids. Diffuse alveolar bleeding has occasionally been reported in adults with Henoch-Schönlein purpura; this is the first report from the Netherlands.
Stienstra
Y
Y
Afd. Interne Geneeskunde-Intensive Care Beademing, Academisch Ziekenhuis, Groningen.
Fijen
J W
JW
Tervaert
J W
JW
Dankbaar
H
H
Zijlstra
J G
JG
van der Werf
T S
TS
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D017563:Lung Diseases, Interstitial / Q000209:etiology*; D011650:Pulmonary Alveoli / Q000473:pathology; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000209:etiology*; D016896:Treatment Outcome