Prevalence of autoantibodies against contractile proteins in coronary artery disease and their clinical implications.
In this initial study, we found that autoantibodies against actin and myosin were present during and after an acute coronary syndrome. Moreover, they correlated with persistent troponin-I elevation at follow-up, and with late myocardial infarction.
Dangas
G
G
Cardiovascular Research Foundation, New York, New York 10022, USA. gdangas@compuserve.com
Konstadoulakis
M M
MM
Epstein
S E
SE
Stefanadis
C I
CI
Kymionis
G D
GD
Toutouza
M G
MG
Liakos
C
C
Sadaniantz
A
A
Cohen
A M
AM
Chesebro
J H
JH
Toutouzas
P K
PK
D000199:Actins / Q000276:immunology*; D000208:Acute Disease; D001323:Autoantibodies / Q000032:analysis*; D015415:Biomarkers / Q000097:blood; D003327:Coronary Disease / Q000097:blood / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009218:Myosins / Q000276:immunology*; D015995:Prevalence; D011379:Prognosis; D019210:Troponin I / Q000276:immunology*
D000199:Actins; D001323:Autoantibodies; D015415:Biomarkers; D019210:Troponin I; D009218:Myosins