Selecting antihypertensive therapy in the pregnant woman with diabetes mellitus.
The choice of an antihypertensive agent for the pregnant woman with diabetes involves many factors. We seek to avoid adverse fetal effects while optimizing maternal outcome, both short- and long-term. This article examines the existing literature to define therapeutic goals of antihypertensive therapy during pregnancy as compared to the therapeutic goals of antihypertensive therapy in the setting of diabetes mellitus and to integrate this information for the treatment of pregnant women in whom diabetes mellitus and hypertension coexist.
Conway
D L
DL
Department of Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio 78284, USA. conway@uthscsa.edu
Longer
O
O
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D005313:Fetal Death / Q000139:chemically induced; D005333:Fetus / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000209:etiology; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000150:complications*
D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers