Etretinate in the management of harlequin siblings.
Harlequin fetus is the severe form of congenital ichthyosis. There are very few reports of babies with this condition surviving the first few weeks of life. We treated two siblings who lived for 22 months and six weeks respectively. We started treatment with oral etretinate every early in their lives and achieved good improvement in the skin condition of these babies.
Pejaver
R K
RK
Department of Pediatrics, North West Armed Forces Hospital Tabuk, Saudi Arabia.
Prasad
R S
RS
Garg
A K
AK
Jelly
A
A
Shawkat
S
S
D000284:Administration, Oral; D005050:Etretinate / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006801:Humans; D017490:Ichthyosis, Lamellar / Q000188:drug therapy* / Q000235:genetics; D007223:Infant; D007231:Infant, Newborn; D007641:Keratolytic Agents / Q000008:administration & dosage*
D007641:Keratolytic Agents; D005050:Etretinate