Glucosylcaldarchaetidylglycerol, a minor phosphoglycolipid from Thermoplasma acidophilum.
A novel phosphoglycolipid (GPL-K) was isolated from Thermoplasma acidophilum (ATCC 27658). The chemical components of GPL-K were analyzed by gas liquid chromatography and GC-MS. The sugar moiety of GPL-K and its anomeric region were analyzed by NMR assignment. The core lipid of GPL-K was caldarchaeol, and its main hydrocarbon chains were acyclic and monocyclic C(40) biphytanyl. The polar head groups were alpha-glucose and glycerophosphate. The negative FAB-MS spectrum of GPL-K confirmed that the lipid peak of m/z 1614 consists of a caldarchaeol (including one cyclopentane ring), a hexose sugar, and a glycerophosphate. We have proposed the tentative structure of GPL-K.
Uda
I
I
Division of Chemistry, Center for Natural Science, Kitasato University, 1-15-1 Kitasato, Sagamihara, Kanagawa, Japan. uda@cals.kitasato-u.ac.jp
Sugai
A
A
Shimizu
A
A
Itoh
Y H
YH
Itoh
T
T
D002240:Carbohydrate Sequence; D002855:Chromatography, Thin Layer; D008401:Gas Chromatography-Mass Spectrometry; D005994:Glycerophosphates / Q000737:chemistry; D005995:Glyceryl Ethers / Q000737:chemistry; D006017:Glycolipids / Q000737:chemistry / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010743:Phospholipids / Q000737:chemistry / Q000378:metabolism*; D013822:Thermoplasma / Q000378:metabolism*
D005994:Glycerophosphates; D005995:Glyceryl Ethers; D006017:Glycolipids; D010743:Phospholipids; C094418:caldarchaeol; C409646:glucosylcaldarchaetidylglycerol