Rabbit and monkey visual cortex: more than a year of recording with up to 64 microelectrodes.
In the visual cortex of rabbits and a marmoset monkey, 32 and 64 microwires, respectively, were chronically implanted by an indirect insertion method so that the cortex was penetrated from the white matter. For more than 1 year recordings of action potentials of good quality were obtained at most electrodes. Recording stability was judged by spike shape, spike train autocorrelograms, and spike rates: within recording sessions, stability was essentially perfect. Periods in which the signals of several electrodes were stable could last for several days. A method of in vivo reconstruction of the electrode locations by micro-X-rays and subsequent stereophotogrammetry is presented. The aspect of animal welfare is considered.
Porada
I
I
Institut für Biophysik, AG Hirnforschung, Universität Freiburg, Germany.
Bondar
I
I
Spatz
W B
WB
Krüger
J
J
D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D002144:Callithrix; D008839:Microelectrodes; D009474:Neurons / Q000502:physiology*; D011817:Rabbits; D014793:Visual Cortex / Q000502:physiology*