New therapies for systemic lupus erythematosus.
New therapies for the treatment of SLE have gained increased attention, as demonstrated by a growing number of new modalities being studied. These modalities include novel biologic agents that target specific immunologic responses and more traditional pharmaceutical agents. This article summarizes these new therapies and briefly discusses their mechanisms of action and the most recent research performed to characterize their safety and efficacy.
Strand
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Division of Immunology, Stanford University Medical Center, California, USA. vstrand@aol.com
D000936:Antigen-Antibody Complex; D003167:Complement Activation; D016207:Cytokines / Q000627:therapeutic use; D004247:DNA / Q000276:immunology; D006801:Humans; D007167:Immunotherapy / Q000639:trends*; D008180:Lupus Erythematosus, Systemic / Q000628:therapy*; D008213:Lymphocyte Activation; D013601:T-Lymphocytes / Q000276:immunology
D000936:Antigen-Antibody Complex; D016207:Cytokines; D004247:DNA