title: An earlier menopause as clinical manifestation of granulosa-cell tumor: a case report.
abstract: We present a case of a granulosa-cell tumor, which can cause menopause at an earlier than normal age. The hormonal profiles were characterized by undetectable FSH levels associated with an estradiol level compatible with the level seen in perimenopausal women and by a significant increase in the inhibin level.
authors.affiliation: Department of Obstetrics and Gynecology, University of Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Hiroi
authors.forename: M
authors.initials: M
authors.lastname: Momoeda
authors.forename: N
authors.initials: N
authors.lastname: Yamauchi
authors.forename: Y
authors.initials: Y
authors.lastname: Abe
authors.forename: H
authors.initials: H
authors.lastname: Yoshikawa
authors.forename: O
authors.initials: O
authors.lastname: Tsutsumi
authors.forename: Y
authors.initials: Y
authors.lastname: Taketani
mesh_terms: D003937:Diagnosis, Differential; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006106:Granulosa Cell Tumor / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007265:Inhibins / Q000032:analysis / Q000097:blood; D008594:Menopause, Premature; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery
chemical_list: D004958:Estradiol; D007265:Inhibins; D005640:Follicle Stimulating Hormone