Structure and synthesis of the first procassinidin dimers based on epicatechin, and gallo- and epigallo-catechin.
The range of natural dimeric procassinidins is extended by identification of cassiaflavan-(4alpha-->8)-epicatechin, cassiaflavan-(4alpha 8)-epigallocatechin, cassiaflavan-(4beta-->8)-epicatechin, cassiaflavan-(4beta-->8)-epigallocatechin, cassiaflavan-(4beta-->8)-gallocatechin, ent-cassiaflavan-(4beta-->8)-epicatechin and cassiaflavan-(4alpha-->6)-epicatechin in the bark of Cassia petersiana. Their structures and absolute configuration were confirmed by synthesis.
Coetzee
J
J
Department of Chemistry, University of the Orange Free State, Bloemfontein, South Africa. coetzeej@cem.nw.uovs.ac.za
Mciteka
L
L
Malan
E
E
Ferreira
D
D
D002366:Cassia / Q000737:chemistry; D002392:Catechin / Q000138:chemical synthesis / Q000737:chemistry*; D019281:Dimerization; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal
D002392:Catechin