title: Beta-adrenoceptor agonists in bronchial asthma: role of k+-channel opening in mediating their bronchodilator effects.
authors.affiliation: Smooth Muscle Research Group, School of Biological Sciences, University of Manchester, UK.
authors.forename: R C
authors.initials: RC
authors.lastname: Small
authors.forename: P
authors.initials: P
authors.lastname: Chiu
authors.forename: S J
authors.initials: SJ
authors.lastname: Cook
authors.forename: R W
authors.initials: RW
authors.lastname: Foster
authors.forename: L
authors.initials: L
authors.lastname: Isaac
mesh_terms: D058671:Adrenergic beta-1 Receptor Antagonists; D058672:Adrenergic beta-2 Receptor Antagonists; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology / Q000627:therapeutic use*; D000420:Albuterol / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D018927:Anti-Asthmatic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy* / Q000378:metabolism; D001993:Bronchodilator Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000494:pharmacology; D015220:Calcium Channels / Q000187:drug effects; D020013:Calcium Signaling / Q000187:drug effects; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D018999:Charybdotoxin / Q000494:pharmacology; D006168:Guinea Pigs; D006801:Humans; D017136:Ion Transport / Q000187:drug effects; D007545:Isoproterenol / Q000494:pharmacology / Q000627:therapeutic use; D009126:Muscle Relaxation / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects* / Q000378:metabolism; D009543:Nifedipine / Q000494:pharmacology; D010455:Peptides / Q000494:pharmacology; D011188:Potassium / Q000378:metabolism*; D015221:Potassium Channels / Q000187:drug effects*; D017265:Procaterol / Q000494:pharmacology / Q000627:therapeutic use; D013726:Terbutaline / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D058671:Adrenergic beta-1 Receptor Antagonists; D058672:Adrenergic beta-2 Receptor Antagonists; D000319:Adrenergic beta-Antagonists; D018927:Anti-Asthmatic Agents; D001993:Bronchodilator Agents; D002121:Calcium Channel Blockers; D015220:Calcium Channels; D010455:Peptides; D015221:Potassium Channels; D018999:Charybdotoxin; C064719:iberiotoxin; D009543:Nifedipine; D007545:Isoproterenol; D013726:Terbutaline; D000420:Albuterol; D011188:Potassium; D017265:Procaterol