title: Intra-ocular pressure and haemodynamic changes after tracheal intubation and extubation: a comparative study in glaucomatous and nonglaucomatous children.
abstract: This prospective, controlled study was conducted to compare the effects of tracheal intubation and extubation on intra-ocular pressure changes and haemodynamic parameters in paediatric patients with and without glaucoma. The children were scheduled for intra-ocular surgery. Twenty children with normal intra-ocular pressure and 15 with glaucoma were studied. A standardised general anaesthetic was administered to both groups. After 5 min of anaesthesia, intra-ocular pressure, heart rate and noninvasive blood pressure were measured. These measurements were repeated 30 s and 2 min after tracheal intubation. Further measurements were taken before, and 30 s and 2 min after extubation. The increase in intra-ocular pressure after intubation was greater in the glaucomatous group than in the normal group. The increase in intra-ocular pressure was greater after extubation than intubation in both groups, but was similar in the two groups. However, because of the already increased intra-ocular pressure in glaucomatous children, they may be at an increased risk of visual damage after intubation and extubation.
authors.affiliation: Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: R
authors.initials: R
authors.lastname: Madan
authors.forename: P
authors.initials: P
authors.lastname: Tamilselvan
authors.forename: S
authors.initials: S
authors.lastname: Sadhasivam
authors.forename: D
authors.initials: D
authors.lastname: Shende
authors.forename: V
authors.initials: V
authors.lastname: Gupta
authors.forename: H L
authors.initials: HL
authors.lastname: Kaul
mesh_terms: D000768:Anesthesia, General; D002648:Child; D002675:Child, Preschool; D020878:Device Removal / Q000009:adverse effects; D005260:Female; D005901:Glaucoma / Q000503:physiopathology* / Q000601:surgery; D006439:Hemodynamics; D006801:Humans; D007429:Intraocular Pressure; D007442:Intubation, Intratracheal; D008297:Male