title: [Oxcarbazepine in the treatment of drug-resistant epilepsy in children and adolescents: preliminary study].
abstract: A comparative study was conducted to evaluate the efficacy and tolerability of oxcarbazepine administration in patients with a diagnosed intractable epilepsy with simple partially and complex seizures secondarily generalised. There were 12 patients aged between 2-23 treated in Outpatients' Neurological Department for Children and Adolescents in Poznań. Oxcarbazepine was applied as an add-on therapy in all patients. The drug was administered in 3 daily dose. The doses of oxcarbazepine were evaluated as well as the occurrence of adverse effects was recorded. Four patients presented over 50% reduction of seizures. During the whole period of observation there was no occurrence of adverse effects associated with the inclusion of oxcarbazepine as add-on drug.
authors.affiliation: Katedra i Klinika Neurologii Wieku Rozwojowego AM w Poznaniu.
authors.forename: A
authors.initials: A
authors.lastname: Kluczyński
mesh_terms: D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D002220:Carbamazepine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004351:Drug Resistance; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D000078330:Oxcarbazepine; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine; D000078330:Oxcarbazepine