Artificial DNAs with metal-assisted base pairs.
Two types of artificial beta-C-nucleosides, 2 and 3, were newly synthesized, which possess a metal chelating site (2-aminophenol and catechol, respectively) at the nucleobase moiety. These nucleosides are expected to form metal-assisted base pairs in oligonucleotides and thereby to control high-order structures and functions of DNAs.
Tanaka
K
K
Department of Chemistry, School of Science, The University of Tokyo, Japan.
Cao
H
H
Tasaka
M
M
Shionoya
M
M
D000627:Aminophenols; D020029:Base Pairing; D002396:Catechols; D002614:Chelating Agents; D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D009690:Nucleic Acid Conformation; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry
D000627:Aminophenols; D002396:Catechols; D002614:Chelating Agents; D009705:Nucleosides; C027667:2-aminophenol; D004247:DNA; C034221:catechol