title: Use of N-butyl-2-cyanoacrylate in oral surgery: biological and clinical evaluation.
abstract: N-butyl-2-cyanoacrylate based tissue adhesive, Tisuacryl, was employed as a nonsuture method for closing wounds in oral surgery. One hundred thirty patients were treated with the adhesive and 30 with suture. The surgical procedures were apicectomy, extraction of molars, and mucogingival grafting. The studied product was well tolerated by the tissue and permitted immediate hemostasis and normal healing of incisions. When Tisuacryl was used as dressing material for donor sites and mucosal ulcerations, pain relief was observed.
authors.affiliation: Clínica Estomatológica Docente de Bauta, Provincia Habana; and Centre of Biomaterials of Havana University, Havanna, Cuba.
authors.forename: M
authors.initials: M
authors.lastname: Pérez
authors.forename: I
authors.initials: I
authors.lastname: Fernández
authors.forename: D
authors.initials: D
authors.lastname: Márquez
authors.forename: R M
authors.initials: RM
authors.lastname: Bretaña
mesh_terms: D000328:Adult; D000700:Analgesics / Q000627:therapeutic use; D001047:Apicoectomy; D001684:Biological Dressings; D004659:Enbucrilate / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D005881:Gingiva / Q000637:transplantation; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008963:Molar / Q000601:surgery; D009061:Mouth Mucosa / Q000637:transplantation; D019647:Oral Surgical Procedures; D019226:Oral Ulcer / Q000188:drug therapy; D010149:Postoperative Pain / Q000188:drug therapy; D011446:Prospective Studies; D013536:Suture Techniques; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014081:Tooth Extraction; D014945:Wound Healing
chemical_list: D000700:Analgesics; D006490:Hemostatics; D014014:Tissue Adhesives; D004659:Enbucrilate