title: [Duodenogastric reflux in humans].
abstract: Human duodenogastric reflux (DGR) was comprehensively studied via measurement of gastric juice bile acid levels, manometric, endoscopic and X-ray study in health and benign gastrointestinal diseases and during exercise. DRG is shown to fall in the physiological events that have a biologically determined circadian rhythm. There was an association of DGR with gastric secretion. The "refluctant dilution effect" was established which along with elimination provides a relative constancy of the concentrations of bile ACIDS FROM 0.025 TO 0.422 NG/ML. DGR regulation is effected by the coordinated motor and evacuatory performance of the gastroduodenal junction and duodenum which is described as a lock two-way system. It is concluded that DGR is involved in the formation of the internal gastric environment and hence plays a role in gastric digestion. The findings may be used in studies of the physiology of digestion and in clinical practice.
authors.forename: V F
authors.initials: VF
authors.lastname: Chernov
authors.forename: A P
authors.initials: AP
authors.lastname: Kuznetsov
authors.forename: A V
authors.initials: AV
authors.lastname: Danilova
authors.forename: Z A
authors.initials: ZA
authors.lastname: Beriashvili
authors.forename: A V
authors.initials: AV
authors.lastname: Chernov
mesh_terms: D000293:Adolescent; D000328:Adult; D001647:Bile Acids and Salts / Q000032:analysis; D002940:Circadian Rhythm; D004063:Digestion; D004383:Duodenogastric Reflux / Q000175:diagnosis / Q000503:physiopathology; D004724:Endoscopy; D005260:Female; D005750:Gastric Juice / Q000737:chemistry / Q000502:physiology; D006801:Humans; D008297:Male; D008365:Manometry
chemical_list: D001647:Bile Acids and Salts