Update on hereditary optic neuropathy.
Although no treatment is available for hereditary optic neuropathies, recent localization and identification of some of the genetic loci have helped the evaluation and management of patients with these disorders. This article discusses the clinical features and known genetic information regarding Leber's hereditary optic neuropathy, dominant optic atrophy, recessive optic atrophy, and Wolfram syndrome.
Yen
M T
MT
Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA.
Lam
B L
BL
D001296:Audiovisual Aids; D004272:DNA, Mitochondrial / Q000235:genetics; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D005838:Genotype; D006801:Humans; D009154:Mutation; D015418:Optic Atrophies, Hereditary / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D010641:Phenotype; D058609:Visual Field Tests; D014794:Visual Fields
D004272:DNA, Mitochondrial