[Early relapse of herpes simplex encephalitis. Clinical and therapeutic implications].
A case of Herpes simplex virus encephalitis (HSVE) is reported in a 5 year old boy, who relapsed twice during the acute phase of the disease. The second relapse was completely cured by increasing the daily treatment with acyclovir to a dosage of 60 mg/kg intravenously for two weeks and 30 mg/kg by mouth for a further week. The full disappearance of the symptoms and the regression of cerebral lesions could be correlated to a prompt diagnosis and to the dosage of acyclovir employed, higher than that suggested for diseases caused that was by other members of the Herpes virus family.
Pavone
P
P
Dipartimento di Pediatria, Università degli Studi, Catania.
Trobia
G L
GL
Ruggieri
M
M
Greco
F
F
D'Agata
A
A
Musumeci
S
S
D001921:Brain / Q000473:pathology; D002675:Child, Preschool; D020803:Encephalitis, Herpes Simplex / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012008:Recurrence