title: Testing a BEIR-VI suggestion for explaining the lung cancer vs. radon relationship for U.S. counties.
abstract: The BEIR-VI Report suggests that the large discrepancy between the observed lung cancer rate vs. radon exposure relationship for U.S. counties, and the predictions of linear no-threshold theory, may be explained by a strong negative correlation between smoking intensity and radon exposure. It proposes a model for testing that suggestion. We apply that model to the detailed data for U.S. counties; analysis shows that even a perfect negative correlation explains little more than half of the discrepancy, and the largest not-implausible correlation can explain less than a quarter of the discrepancy. We then extend the BEIR-VI suggestion to include a strong negative correlation between both the prevalence of smoking and the intensity of smoking. The largest not-implausible correlations can explain no more than 30% of the discrepancy. It is concluded that the previous interpretation of these data, that linear no-threshold theory fails this test, is sustained.
authors.affiliation: University of Pittsburgh, Department of Physics, PA 15260, USA. blc+@pitt.edu
authors.forename: B L
authors.initials: BL
authors.lastname: Cohen
mesh_terms: D006283:Health Physics; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000209:etiology*; D015233:Models, Statistical; D011886:Radon / Q000009:adverse effects*; D014481:United States / Q000453:epidemiology
chemical_list: D011886:Radon