title: Surgical management of angiomyolipoma: nephron-sparing surgery for symptomatic tumour.
abstract: Angiomyolipoma (AML) is a benign renal tumour that occasionally requires intervention. We evaluated the surgical management of symptomatic angiomyolipoma, with special attention to the feasibility of nephron-sparing surgery. A retrospective study was conducted enlisting 23 patients (including 3 patients with tuberous sclerosis) who had their AML treated surgically from 1991 to 1998. The study included 7 males and 16 females, with a mean age of 49 years (range 24-75). The mean tumour size was 12.3 cm (range 1.5-30.0) including 7 lesions < or = 4 cm and 16 lesions > 4 cm. The presenting features included abdominal/loin pain (9 patients), spontaneous rupture (5 patients), non-specific symptoms (7 patients) and incidental findings (2 patients). AML was diagnosed by computed tomography in 16 patients and malignancy was suspected in 7 patients. The latter group included 5 patients with lesions smaller than 4 cm, one of them having coexisting AML and renal cell carcinoma. All patients underwent elective surgery, with the exception of one, who required a semi-emergency operation. Nephron-sparing surgery using frozen section in 5 patients (all diagnostic) was carried out on 16 patients, including all 5 patients with previous haemorrhage and 2 patients with suspected lesions from preoperative studies. Total nephrectomy was performed in 7 patients, including the other 5 patients with lesions suspected to be malignant. There was no operative mortality. Two complications were encountered in the entire group. We conclude that elective nephron-sparing surgery is feasible, even for massive angiomyolipoma or after previous rupture, especially when the diagnosis is made by preoperative imaging and/or intraoperative frozen section.
authors.affiliation: Department of Urology, Singapore General Hospital, Singapore. gurykh@sgh.gov.sg
authors.forename: S K
authors.initials: SK
authors.lastname: Yip
authors.forename: P H
authors.initials: PH
authors.lastname: Tan
authors.forename: W S
authors.initials: WS
authors.lastname: Cheng
authors.forename: M K
authors.initials: MK
authors.lastname: Li
authors.forename: K T
authors.initials: KT
authors.lastname: Foo
mesh_terms: D000328:Adult; D000368:Aged; D018207:Angiomyolipoma / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007677:Kidney Function Tests; D007680:Kidney Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D011183:Postoperative Complications / Q000175:diagnosis; D012189:Retrospective Studies; D014402:Tuberous Sclerosis / Q000601:surgery