Collectins and innate immunity in the lung.
Evidence from both in vitro and in vivo studies suggests that the collectins are important elements in host innate immune defences against infectious agents. Study of the collectins in specific disease settings now raises the prospects of developing therapies exploiting these mechanisms of innate immunity.
Clark
H W
HW
Medical Research Council Immunochemistry Unit, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, UK.
Reid
K B
KB
Sim
R B
RB
D000818:Animals; D001419:Bacteria / Q000276:immunology; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics / Q000276:immunology*; D037222:Collectins; D005658:Fungi / Q000276:immunology; D006801:Humans; D007109:Immunity; D008168:Lung / Q000276:immunology*; D008171:Lung Diseases / Q000276:immunology / Q000382:microbiology; D051379:Mice; D018345:Mice, Knockout; D011663:Pulmonary Surfactants / Q000276:immunology; D012307:Risk Factors; D014780:Viruses / Q000276:immunology
D002352:Carrier Proteins; D037222:Collectins; D011663:Pulmonary Surfactants