title: High uptake of 123I-metaiodobenzylguanidine related to olfactory neuroblastoma revealed by single-photon emission CT.
abstract: We studied a case of olfactory neuroblastoma by noting 123I-metaiodobenzylguanidine (MIBG) uptake revealed by single-photon emission CT (SPECT). MR imaging revealed an enhancing tumor extending from the left nasal cavity to the bilateral anterior frontal cranial fossae. SPECT revealed high 123I-MIBG uptake in the enhancing tumor. SPECT-revealed 123I-MIBG uptake appears to be clinically useful for distinguishing olfactory neuroblastomas from other tumors, especially suprasellar meningiomas.
authors.affiliation: Neurosurgical Service, Akita University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Sasajima
authors.forename: H
authors.initials: H
authors.lastname: Kinouchi
authors.forename: N
authors.initials: N
authors.lastname: Tomura
authors.forename: J
authors.initials: J
authors.lastname: Watarai
authors.forename: K
authors.initials: K
authors.lastname: Mizoi
mesh_terms: D019797:3-Iodobenzylguanidine / Q000493:pharmacokinetics*; D000368:Aged; D006801:Humans; D008297:Male; D009296:Nasal Cavity; D009447:Neuroblastoma / Q000175:diagnosis* / Q000378:metabolism*; D009669:Nose Neoplasms / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine