title: Melanotic differentiation in dysembryoplastic neuroepithelial tumor.
abstract: Dysembryoplastic neuroepithelial tumor (DNT) is an uncommon intracranial tumor which is usually encountered in patients with medically intractable complex partial seizures of temporal lobe origin. Melanotic differentiation in a DNT has not been reported previously. Herewith we report a case of DNT with unique melanotic differentiation in a 23-year-old female who presented with medically intractable epilepsy. She underwent craniotomy and tumor decompression with a good outcome. We present the histopathological features of DNT with melanotic differentiation and discuss its prognostic significance.
authors.affiliation: Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
authors.forename: J
authors.initials: J
authors.lastname: Elizabeth
authors.forename: R M
authors.initials: RM
authors.lastname: Bhaskara
authors.forename: V V
authors.initials: VV
authors.lastname: Radhakrishnan
authors.forename: K
authors.initials: K
authors.lastname: Radhakrishnan
authors.forename: S V
authors.initials: SV
authors.lastname: Thomas
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D017029:Epilepsy, Complex Partial / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D018242:Neuroectodermal Tumors, Primitive / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D011612:Psychosurgery; D013702:Temporal Lobe / Q000473:pathology* / Q000601:surgery