title: Profuse variceal hemorrhage as a presenting feature of pancreatic adenocarcinoma in a young non-icteric patient.
abstract: Pancreatic adenocarcinoma can present with a vast spectrum of rare manifestations. It usually occurs after the age of 50 years, the peak incidence being in sixth and seventh decades. We report a previously asymptomatic subject of pancreatic adenocarcinoma who presented for the first time with massive upper gastrointestinal hemorrhage. Endoscopy revealed ruptured esophageal varices which were secondary to tumour-induced thrombosis of the portal vein. Besides the uncommon mode of presentation, the patient was unusual because of his young age. Further, he was non-icteric at the time of presentation and remained so throughout the clinical course despite having a large lesion in the head of the pancreas.
authors.affiliation: Dept. of Medicine, Maulana Azad Medical College, New Delhi, India.
authors.forename: A
authors.initials: A
authors.lastname: Jain
authors.forename: S
authors.initials: S
authors.lastname: Jain
authors.forename: V
authors.initials: V
authors.lastname: Chowdhury
authors.forename: S
authors.initials: S
authors.lastname: Mukhopadhyay
authors.forename: A
authors.initials: A
authors.lastname: Aggarwal
authors.forename: P
authors.initials: P
authors.lastname: Kar
mesh_terms: D000230:Adenocarcinoma / Q000150:complications*; D000328:Adult; D004932:Esophageal and Gastric Varices / Q000209:etiology*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000150:complications*; D011169:Portal Vein; D020246:Venous Thrombosis / Q000209:etiology