[Hydrazide derivatives with biologically active 1,2,4-triazole support].
This study presents the synthesis of ten new hydrazides with 1,2,4-triazole support. The structures of the obtained compounds were elucidates by means of the elemental analysis data as well as by IR spectral measurements. The antimicrobial and antifungal actions of this derivates are also tested. The results show that the compounds with the functional group 4-chlore-2-methoxyphenyle are more active.
Ungureanu
M
M
Université de Médecine et Pharmacie Gr. T. Popa, Iaşi.
Ciugureanu
C
C
Sunel
V
V
Grosu
G
G
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D008826:Microbial Sensitivity Tests / Q000706:statistics & numerical data; D013329:Structure-Activity Relationship; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D014230:Triazoles