title: [Environmental factors and human reproductive system].
abstract: Problems concerning regularities and mechanisms of the environmental factor influence on human reproductive system are discussed. It is indicated that the response of reproductive system to external challenges is based on the evolutionary formed links between the structures responsible for reproductive organ function (epiphysis, hypothalamus, pituitary), the nature of environmental factors and the regularities of their changes depending on the season and geographical location. Damaging external challenges caused by biosphere pollution by waste products of human economic activity and extreme ecological conditions are realized both by direct influence on target tissues (ionizing radiation) and indirectly through neuroendocrine mechanisms regulating reproductive organs function. Factors and regularities of the development of diseases and pathological conditions of human reproductive system, caused by external challenge including the injurious industrial factor influence were analyzed.
authors.affiliation: Baltic Institute of Human Reproductology, St. Petersburg.
authors.forename: A I
authors.initials: AI
authors.lastname: Nikitin
mesh_terms: D000818:Animals; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D005835:Genitalia / Q000473:pathology / Q000503:physiopathology / Q000528:radiation effects; D005843:Geography; D006801:Humans; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012098:Reproduction / Q000502:physiology* / Q000528:radiation effects; D012621:Seasons