Intra-arterial thrombolysis for the treatment of perioperative childhood cardioembolic stroke.
Local intra-arterial lysis using recombinant tissue plasminogen activator (rTPA) was performed in a 6 and 2/3-year-old patient with major cardioembolic ischemic stroke 48 hours after intracardiac surgery. Selective application of 2.5 mg rTPA (0.11 mg/kg body weight) resulted in recanalization of the occluded cerebral vasculature with good neurologic recovery.
Gruber
A
A
Departments of Neurosurgery, University of Vienna Medical School, Austria.
Nasel
C
C
Lang
W
W
Kitzmüller
E
E
Bavinzski
G
G
Czech
T
T
D006348:Cardiac Surgical Procedures / Q000009:adverse effects; D002533:Cerebral Angiography; D002648:Child; D005260:Female; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D015552:Injections, Intralesional; D008279:Magnetic Resonance Imaging; D011183:Postoperative Complications / Q000209:etiology / Q000628:therapy; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D010959:Tissue Plasminogen Activator