title: [Early respiratory support in anti-shock therapy of children with severe thermal trauma].
abstract: Search for effective method for decreasing the mortality of children with severe thermal injuries and approaches to preventing and treating multiorgan dysfunction in severe thermal injury is a pressing problem of reanimatology. The majority of scientists consider disorders in the ventilation-perfusion function of the lungs the main factor in the pathogenesis of burn shock. Lung injury is most often the first manifestation of multiple organ dysfunction. The depth of disorders in the gas exchange function of the lungs clearly correlates with the severity of burn injury and the terms of the beginning of respiratory support. The severity of burn shock, preclinical diagnosis of acute respiratory distress syndrome and disseminated intravascular blood coagulation, depth of hemodynamic disorders and disorders in the oxygen transporting system can serve as a criterion of the compensatory stress and be an indication for active respiratory therapy. Comparison of the main and control groups demonstrated the efficiency of early respiratory therapy in children with severe burns, because such therapy normalizes the blood oxygen transporting function and hemodynamic parameters sooner and with less strain for the compensatory potential of the organism.
authors.forename: V M
authors.initials: VM
authors.lastname: Egorov
authors.forename: N P
authors.initials: NP
authors.lastname: Nasonova
authors.forename: V M
authors.initials: VM
authors.lastname: Odinak
mesh_terms: D000293:Adolescent; D002056:Burns / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D007902:Length of Stay; D008297:Male; D009102:Multiple Organ Failure / Q000517:prevention & control; D012121:Respiration, Artificial; D012774:Shock, Traumatic / Q000209:etiology / Q000517:prevention & control* / Q000628:therapy; D013997:Time Factors