title: Early surgical suction and washout for treatment of cytotoxic drug extravasations.
abstract: This case report is presented to assess safety and efficiency of early suction and saline washout of extravasated cytotoxic drugs. Through multiple small skin incisions, the area of extravasation is first suctioned and subsequently extensively washed out with saline. Incisions are left open and the arm is elevated for 24 hours. A complete healing was obtained in five days without any skin or soft tissue loss. No additional treatment was needed. Early referral and surgical treatment by suction and washout is a safe and reliable treatment protocol for major cytotoxic drug extravasation injuries.
authors.affiliation: Plastic and Reconstructive Surgery Department, Jules Bordet Cancer Institute, Bruxelles, Belgium.
authors.forename: E
authors.initials: E
authors.lastname: Vandeweyer
authors.forename: R
authors.initials: R
authors.lastname: Deraemaecker
mesh_terms: D000328:Adult; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects*; D004317:Doxorubicin / Q000008:administration & dosage / Q000009:adverse effects*; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000209:etiology* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005543:Forearm Injuries / Q000209:etiology* / Q000601:surgery*; D006801:Humans; D007262:Infusions, Intravenous / Q000009:adverse effects; D013396:Suction / Q000379:methods; D007507:Therapeutic Irrigation / Q000379:methods; D014945:Wound Healing / Q000502:physiology
chemical_list: D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin