[N-acetyl-beta-glucosaminidase (NAG) activity in parturients with placental insufficiency in postmature pregnancy and with EPH-gestosis].
NAG activity evaluation was carried out in parturients' blood and placental homogenates in regular pregnancies (n = 46) and complicated with biological postmaturity (n = 30) and EPH-gestosis (n = 24). It was revealed that in the blood of parturients with pregnancy complicated with gestosis there was considerable increase of NAG activity (2.43 +/- 1.02 microKat/kg). Lower activity level was found in parturients with entopic pregnancy (1.93 +/- 0.87 microKat/kg), and the lowest in those with postmature pregnancy (1.78 +/- 0.56 microKat/kg). The placental homogenates presented statistically significant differences--the highest in postmature pregnancy (6.37 +/- 2.01 mKat/kg), lower in pregnancy complicated with gestosis (4.85 +/- 1.52 mKat/kg) and the lowest in normal pregnancy (3.52 +/- 1.21 mKat/kg). The elevated activity in blood serum of parturient with gestosis may indicate kidney damage in the course of disease. High activity in homogenate may indicate the processes of placental degradation in postmature pregnancy. There is no evidence of correlation between NAG activity in blood and activity in placental tissue.
Bielecki
M
M
Kliniki Połoznictwa, Akademii Medycznej w Białymstoku.
Południewski
G
G
Arciszewski
K
K
Zwierz
K
K
D000118:Acetylglucosaminidase / Q000097:blood*; D000328:Adult; D005260:Female; D006801:Humans; D010924:Placental Extracts / Q000737:chemistry; D010927:Placental Insufficiency / Q000150:complications* / Q000201:enzymology*; D011225:Pre-Eclampsia / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications
D010924:Placental Extracts; D000118:Acetylglucosaminidase