Epilepsy and associated psychopathology in young people with intellectual disability.
OBJECTIVE
This study aimed to investigate the role of epilepsy in psychopathology among an epidemiological sample of young people with intellectual disability (ID). The study also compared behavioural and emotional problems in young people on medication to control their epilepsy with those not on medication, and young people with epilepsy who were having current seizure activity with those with no current seizure activity.


METHODS
An epidemiological cohort of 392 participants, representative of the general Australian population of young people with ID, were used in the study. One hundred and fifteen individuals from this cohort were identified as suffering from epilepsy. The Developmental Behaviour Checklist was used to measure symptoms of behavioural and emotional disturbance.


RESULTS
Results confirmed that young people with ID and epilepsy did not differ from controls without epilepsy on measures of psychopathology. Furthermore, those with epilepsy on medication had no difference in levels of problem behaviours than epileptics not on medication.


CONCLUSIONS
The results suggest that epilepsy has little or no influence on problem behaviours for young people with ID. Our attempt to understand the pathogenesis of behaviour problems in persons with ID may be better directed towards understanding genetic mechanisms than epilepsy pathologies.
Lewis
J N
JN
Centre for Developmental Psychiatry, Monash University, Clayton, Victoria, NSW, Australia.
Tonge
B J
BJ
Mowat
D R
DR
Einfeld
S L
SL
Siddons
H M
HM
Rees
V W
VW
D000293:Adolescent; D000328:Adult; D000342:Affective Symptoms / Q000209:etiology*; D002648:Child; D002653:Child Behavior Disorders / Q000209:etiology*; D015331:Cohort Studies; D004827:Epilepsy / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000209:etiology*; D008297:Male