[Effect of co-polymer 2-methyl-5-vinylpyridine and 2-methyl-5- vinylpyridinium-n-oxide radiation induced myelodepression in mice].
On the model of cytopenia induced in mice by irradiation with a dose of 4.0 Gy it was shown that injection of examined copolymer (400 mg/kg) 3 h after irradiation exerts positive effect on haemopoietic system: the decrease of damage and acceleration of repair processes.
Korovkina
E P
EP
Russian State Research Center, Institute of Biophysics, Moscow.
Mikhaĭlov
P P
PP
D000818:Animals; D007962:Leukocytes / Q000187:drug effects / Q000473:pathology; D019891:Leukopoiesis / Q000187:drug effects*; D051379:Mice; D011108:Polymers / Q000008:administration & dosage* / Q000627:therapeutic use; D011725:Pyridines / Q000008:administration & dosage* / Q000627:therapeutic use; D011726:Pyridinium Compounds / Q000008:administration & dosage* / Q000627:therapeutic use; D011833:Radiation Injuries, Experimental / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*
D011108:Polymers; D011725:Pyridines; D011726:Pyridinium Compounds; C019198:2-methyl-5-vinylpyridine