Anaesthesia of the common marmoset (Callithrix jacchus) using continuous intravenous infusion of alphaxalone/alphadalone.
A safe means of anaesthetizing common marmosets (Callithrix jacchus) for a study using magnetic resonance imaging (MRI) to investigate cerebral ischaemia was required. Continuous infusion of alphaxalone/alphadalone was used to anaesthetize 37 marmosets for non-recovery and recovery experiments. This was found to give safe, reliable anaesthesia when coupled with pulse oximetry and electrocardiographic (ECG) monitoring.
Whelan
G
G
SmithKline Beecham Pharmaceuticals, Harlow, Essex, UK.
James
M F
MF
Samson
N A
NA
Wood
N I
NI
D000530:Alfaxalone Alfadolone Mixture / Q000008:administration & dosage* / Q000494:pharmacology; D000771:Anesthesia, Intravenous / Q000379:methods / Q000662:veterinary*; D000818:Animals; D002144:Callithrix / Q000502:physiology* / Q000601:surgery; D004562:Electrocardiography / Q000662:veterinary; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D007262:Infusions, Intravenous / Q000662:veterinary; D008279:Magnetic Resonance Imaging / Q000662:veterinary; D008297:Male; D010092:Oximetry / Q000662:veterinary
D000530:Alfaxalone Alfadolone Mixture