title: Sedation with sufentanil and midazolam decreases pain in patients undergoing upper limb surgery under multiple nerve block.
abstract: Multiple nerve blocks may be painful and a source of discomfort. We assessed the efficacy of sufentanil 5 microg combined with midazolam 1 mg in decreasing pain in outpatients after a midhumeral multiple nerve stimulation technique. Visual analog scores for pain were significantly lower in those patients who received sedation before the block, both at the time of block performance (14 +/- 1 vs 27 +/- 2 mm, P < 0.0001) and at discharge (11 +/- 1 vs 24 +/- 2 mm, P < 0. 0001). We conclude that the association of sufentanil and midazolam produced minimal sedation while significantly reducing pain experienced by patients undergoing multiple nerve stimulation.
authors.affiliation: Department of Anesthesiology and Intensive Care, Centre Hospitalier Universitaire de Bicêtre, Le Kremlin Bicêtre, France.
authors.forename: B P
authors.initials: BP
authors.lastname: Kinirons
authors.forename: H
authors.initials: H
authors.lastname: Bouaziz
authors.forename: X
authors.initials: X
authors.lastname: Paqueron
authors.forename: A
authors.initials: A
authors.lastname: Ababou
authors.forename: C
authors.initials: C
authors.lastname: Jandard
authors.forename: M M
authors.initials: MM
authors.lastname: Cao
authors.forename: M L
authors.initials: ML
authors.lastname: Bur
authors.forename: M C
authors.initials: MC
authors.lastname: Laxenaire
authors.forename: D
authors.initials: D
authors.lastname: Benhamou
mesh_terms: D000328:Adult; D000556:Ambulatory Surgical Procedures; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D001132:Arm / Q000601:surgery*; D016292:Procedural Sedation; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D008297:Male; D008874:Midazolam / Q000008:administration & dosage*; D009407:Nerve Block / Q000009:adverse effects*; D010146:Pain / Q000209:etiology* / Q000517:prevention & control*; D011446:Prospective Studies; D017409:Sufentanil / Q000008:administration & dosage*
chemical_list: D000701:Analgesics, Opioid; D006993:Hypnotics and Sedatives; D017409:Sufentanil; D008874:Midazolam