Cyclodextrin-peptide hybrid as a hydrolytic catalyst having multiple functional groups.
A designed cyclodextrin peptide hybrid, which has multiple functional groups on its alpha-helix peptide backbone, has been synthesized as a catalyst for ester hydrolysis. Kinetic study revealed that the carboxylate group plays a key role in this system.
Tsutsumi
H
H
Department of Bioengineering, Faculty of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan.
Hamasaki
K
K
Mihara
H
H
Ueno
A
A
D000595:Amino Acid Sequence; D002384:Catalysis; D002942:Circular Dichroism; D003505:Cyclodextrins / Q000737:chemistry*; D006868:Hydrolysis; D007700:Kinetics; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
D003505:Cyclodextrins; D010455:Peptides