title: Relative and absolute configurations of ganefromycin alpha.
abstract: The full structure of ganefromycin alpha has been determined. The relative configurations were determined from 3JH,H coupling constants and NOE data, while the absolute configurations in moleties A and B were determined separately by difference CD of their acylate derivatives, which showed typical exciton couplets. The configurations of the stereogenic centers in ganefromycin alpha are 8S, 9S, 11R, 12S, 13S, 21S, 22R, 23R, 24R, and 26S.
authors.affiliation: Department of Chemistry, Columbia University, New York, New York 10027, USA.
authors.forename: T
authors.initials: T
authors.lastname: Andersson
authors.forename: N
authors.initials: N
authors.lastname: Berova
authors.forename: K
authors.initials: K
authors.lastname: Nakanishi
authors.forename: G T
authors.initials: GT
authors.lastname: Carter
mesh_terms: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D002942:Circular Dichroism; D008968:Molecular Conformation; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; C058741:phenelfamycin E