title: Antibiotic resistance trends in enteropathogenic bacteria isolated in 1985-1987 and 1995-1998 in Barcelona.
abstract: Trends in resistance to antimicrobial agents used for therapy have been evaluated with 3,797 enteropathogenic bacteria, Campylobacter, Salmonella, Shigella, and Yersinia, between 1985-1987 and 1995-1998. The greater increase in the rate of resistance was observed in Campylobacter jejuni for quinolones (from 1 to 82%) and tetracycline (from 23 to 72%) and in gastroenteric salmonellae for ampicillin (from 8 to 44%), chloramphenicol (from 1.7 to 26%), and trimethoprim-sulfamethoxazole and nalidixic acid (from less than 0.5 to 11%). Multidrug resistance was detected in several Salmonella serotypes. In the 1995-1998 period, 76% of Shigella strains were resistant to trimethoprim-sulfamethoxazole, 43% were resistant to ampicillin, and 39% were resistant to chloramphenicol. Seventy-two percent of Yersinia enterocolitica O3 strains were resistant to streptomycin, 45% were resistant to sulfonamides, 28% were resistant to trimethoprim-sulfamethoxazole, and 20% were resistant to chloramphenicol.
authors.affiliation: Departament de Microbiologia, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma 08025 Barcelona, Spain. 2175@hsp.santpau.es
authors.forename: G
authors.initials: G
authors.lastname: Prats
authors.forename: B
authors.initials: B
authors.lastname: Mirelis
authors.forename: T
authors.initials: T
authors.lastname: Llovet
authors.forename: C
authors.initials: C
authors.lastname: Muñoz
authors.forename: E
authors.initials: E
authors.lastname: Miró
authors.forename: F
authors.initials: F
authors.lastname: Navarro
mesh_terms: D002167:Campylobacter / Q000187:drug effects / Q000302:isolation & purification; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D012475:Salmonella / Q000187:drug effects / Q000302:isolation & purification; D012760:Shigella / Q000187:drug effects / Q000302:isolation & purification; D013030:Spain; D013997:Time Factors; D015007:Yersinia / Q000187:drug effects / Q000302:isolation & purification