Stephanotic acid, a novel cyclic pentapeptide from the stem of Stephanotis floribunda.
The stem of Stephanotis floribunda afforded a new cyclic pentapeptide stephanotic acid (1), possessing a novel 6-(leucin-3'-yl) tryptophan skeleton. The structure of 1 was assigned on the basis of extensive NMR experiments and a chemical reaction and shown to be closely related to the bicyclic octapeptide moroidin (3), a toxin from Laportea moroides.
Yoshikawa
K
K
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan. yosikawa@ph.bunri-u.ac.jp
Tao
S
S
Arihara
S
S
D008270:Madagascar; D009682:Magnetic Resonance Spectroscopy; D008296:Malaysia; D010456:Peptides, Cyclic / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D010456:Peptides, Cyclic; C409632:stephanotic acid