7-Epicylindrospermopsin, a toxic minor metabolite of the cyanobacterium Aphanizomenon ovalisporum from lake Kinneret, Israel.
A toxic minor metabolite, 7-epicylindrospermopsin (1), was isolated from a culture of the cyanobacterium Aphanizomenon ovalisporum isolated from Lake Kinneret in Israel. Homonuclear and inverse-heteronuclear 2D NMR techniques, as well as HRMS and comparison of the NMR data with model compounds, enabled the structure determination of the new compound. Four polymethoxy-1-alkenes, 3-6, were isolated from the lipophilic extract of the cyanobacterium as well.
Banker
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R
School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel.
Teltsch
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B
Sukenik
A
A
Carmeli
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S
D000470:Alkaloids; D001427:Bacterial Toxins; D000458:Cyanobacteria / Q000378:metabolism*; D000087522:Cyanobacteria Toxins; D015394:Molecular Structure; D013057:Spectrum Analysis; D014498:Uracil / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification
D000470:Alkaloids; D001427:Bacterial Toxins; D000087522:Cyanobacteria Toxins; C089595:cylindrospermopsin; D014498:Uracil