New sesquiterpene/quinones from two sponges of the genus Hyrtios.
Two sponges of the genus Hyrtios have been found to contain new sesquiterpene/quinones identified by detailed spectroscopic analysis. Four new compounds with a 4,9-friedodrim-3-ene skeleton [hyrtiophenol (2), 5-epihyrtiophenol (3), 18-hydroxy-5-epihyrtiophenol (4), and 18-hydroxyhyrtiophenol (5)] were isolated from Hyrtios sp. (Seychelles Islands) along with isospongiaquinone (1). Moreover, the new compound 21-hydroxy-19-methoxyarenarone (8), which bears the 4, 9-friedodrim-4(15)-ene skeleton, was isolated from Hyrtios tubulatus (Curaçao) along with arenarol (6) and 5-epiilimaquinone (7). Assignment of the (13)C NMR signals of four types of 4, 9-friedodrimene skeletons found in sponges is presented.
Salmoun
M
M
Laboratory of Bio-organic Chemistry, Department of Organic Chemistry, Faculty of Sciences, CP 160/07, University of Brussels, Belgium.
Devijver
C
C
Daloze
D
D
Braekman
J C
JC
Gomez
R
R
de Kluijver
M
M
Van Soest
R W
RW
D000107:Acetylation; D000818:Animals; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011161:Porifera / Q000737:chemistry*; D011809:Quinones / Q000302:isolation & purification*; D012717:Sesquiterpenes / Q000302:isolation & purification*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D011809:Quinones; D012717:Sesquiterpenes