title: Suitably functionalised pyrimidines as potential antimycotic agents.
abstract: Various suitably functionalized pyrimidine derivatives have been synthesized to explore their potential as antimycotic agents. Some of the synthesized compounds 4c, 4d, 8a-e have shown highly significant in vitro antifungal activity against five human pathogenic fungi.
authors.affiliation: Division of Medicinal Chemistry, Central Drug Research Institute, Lucknow, India.
authors.forename: N
authors.initials: N
authors.lastname: Agarwal
authors.forename: S K
authors.initials: SK
authors.lastname: Raghuwanshi
authors.forename: D N
authors.initials: DN
authors.lastname: Upadhyay
authors.forename: P K
authors.initials: PK
authors.lastname: Shukla
authors.forename: V J
authors.initials: VJ
authors.lastname: Ram
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D005658:Fungi / Q000145:classification / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests; D011743:Pyrimidines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D013045:Species Specificity
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines