title: Complete disappearance of recurrent hepatocellular carcinoma with peritoneal dissemination and splenic metastasis: a unique clinical course after surgery.
abstract: Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon. We report a case of complete disappearance of intrahepatic, peritoneal and splenic metastases in HCC after hepatectomy using treatment with tegafur and uracil (UFT). The effect of UFT alone was not likely to have caused the disappearance of this tumour because HCC recurrence advance markedly within 5 months of surgery despite oral administration of UFT. This case demonstrates a unique postoperative clinical course that suggests spontaneous regression of HCC. This is the first case of complete disappearance of unresectable HCC with peritoneal seeding and splenic metastasis.
authors.affiliation: Department of Surgery, Asama General Hospital, Saku, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Terasaki
authors.forename: K
authors.initials: K
authors.lastname: Hanazaki
authors.forename: E
authors.initials: E
authors.lastname: Shiohara
authors.forename: Y
authors.initials: Y
authors.lastname: Matsunaga
authors.forename: N
authors.initials: N
authors.lastname: Koide
authors.forename: J
authors.initials: J
authors.lastname: Amano
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D006528:Carcinoma, Hepatocellular / Q000556:secondary / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D004359:Drug Therapy, Combination; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D010534:Peritoneal Neoplasms / Q000503:physiopathology* / Q000556:secondary; D012074:Remission Induction; D013160:Splenic Neoplasms / Q000503:physiopathology* / Q000556:secondary; D005641:Tegafur / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014498:Uracil / Q000627:therapeutic use
chemical_list: D000964:Antimetabolites, Antineoplastic; D005641:Tegafur; D014498:Uracil