[The pre- and postnatal development of the human lung].
The bronchoalveolar structures where studied during the intrauterine evolution by histological sections and pulmonary radiographs. This evolution depends on the degree of "prenatal immaturity" or "dismaturity". I compared my results with data from literature. I estimated the rate of bronchial growth as being not uniform, the most abundant branches being encountered in the basic layers of the inferior lobes, and some peripheral juxta-pleural bronchial bend in right angles, continuing with branches parallel to the pleural surface. I find justified the opinion, increasingly sustained by authors, that the epithelium of the bronchial conduction system has an endothelial origin, while the breathing device originates from the mesenchyme dressing the bronchial distal extremities. However, some pathological aspects, or pulmonary congenital abnormalities, make me sustain this double embryonal origin of the bronchoalveolar structures.
Scutaru
M D
MD
Disciplina de Anatomie, Facultatea de Farmacie, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
D001980:Bronchi / Q000196:embryology / Q000254:growth & development; D005865:Gestational Age; D006801:Humans; D008168:Lung / Q000196:embryology* / Q000254:growth & development*; D009024:Morphogenesis