title: Successful treatment of a patient with nephrotic syndrome associated with chronic lymphocytic leukemia.
abstract: We report the case of a 62-year-old man with nephrotic syndrome associated with stage B chronic lymphocytic leukemia (CLL). Kappa Bence Jones proteinuria and the glomerular deposition of kappa-light chain were observed. Although treatment with cyclophosphamide and prednisolone tended to reduce the level of proteinuria, the administration of angiotensin-converting enzyme inhibitor, enalapril, resulted in complete remission of nephrotic syndrome.
authors.affiliation: First Department of Internal Medicine, Asahikawa Medical College.
authors.forename: F
authors.initials: F
authors.lastname: Takahashi
authors.forename: Y
authors.initials: Y
authors.lastname: Ogawa
authors.forename: N
authors.initials: N
authors.lastname: Hasebe
authors.forename: S
authors.initials: S
authors.lastname: Natori
authors.forename: Y
authors.initials: Y
authors.lastname: Tokusashi
authors.forename: N
authors.initials: N
authors.lastname: Miyokawa
authors.forename: K
authors.initials: K
authors.lastname: Kikuchi
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D001706:Biopsy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004656:Enalapril / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D012074:Remission Induction
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D007166:Immunosuppressive Agents; D004656:Enalapril; D003520:Cyclophosphamide; D011239:Prednisolone