[Is nasal cavity melanoma radioresistant? A case of long term control of neck nodal metastasis by radiotherapy].
Nasal cavity melanoma is a rare neoplasm bearing grave prognosis because of rapid development of local failure and/or distant metastases, which are usually fatal. A case of 56 year old woman, who was referred to Maria Skłodowska Memorial Cancer Institute in Gliwice, Poland, for observation after radical maxillectomy because of nasal cavity melanoma is described. After six months of follow-up she developed large isolated lymphatic metastasis in heterolateral subdigastric node. As a result of administering a course of radical radiotherapy (59 Gy in 24 fractions/30 days) complete remission of this lesion was attained. During next 11 years of follow-up neither locoregional recurrence nor distant metastases were observed. The article describes current suggestions, based on Medline literature search, regarding treatment of isolated nodal melanoma recurrence, with particular emphasis on the possible role of radiotherapy in this clinical setting.
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Oddział Radioterapii, Szpital Onkologiczny im. Jana Pawła II w Bielsku-Białej.
D005260:Female; D006801:Humans; D015182:Lymphatic Irradiation; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000532:radiotherapy* / Q000556:secondary; D008875:Middle Aged; D009296:Nasal Cavity; D009333:Neck; D009669:Nose Neoplasms / Q000473:pathology / Q000532:radiotherapy*