title: [Discovery of highly potent and orally active non-peptide bradykinin B2 receptor antagonists].
authors.affiliation: Medicinal Chemistry Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Osaka, Japan. hiroshi_kayakiri@po.fujisawa.co.jp
authors.forename: H
authors.initials: H
authors.lastname: Kayakiri
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001920:Bradykinin / Q000502:physiology; D065168:Bradykinin Receptor Antagonists; D020650:Combinatorial Chemistry Techniques; D015195:Drug Design; D006801:Humans; D011725:Pyridines / Q000008:administration & dosage / Q000737:chemistry; D011804:Quinolines / Q000008:administration & dosage / Q000737:chemistry; D043782:Receptor, Bradykinin B2; D018002:Receptors, Bradykinin / Q000737:chemistry; D013045:Species Specificity; D013329:Structure-Activity Relationship
chemical_list: D065168:Bradykinin Receptor Antagonists; C106745:FR 167344; C105311:FR 173657; D011725:Pyridines; D011804:Quinolines; D043782:Receptor, Bradykinin B2; D018002:Receptors, Bradykinin; D001920:Bradykinin