[Simultaneous action of UV light and hyperthermia on survival and recombination of yeast: effect of intensity of agents on their synergistic interaction].
Synergistic effects of simultaneous application of ultraviolet (UV) light and hyperthermia on survival and recombination of diploid yeast cells were studied. For both test-systems the dependence of the synergistic interaction on UV light fluence rate and exposure temperature was revealed: the temperature range synergistically increasing the action of UV light is shifted towards low temperature values with decreasing of UV light fluence rate. For cell survival, the dependence of the synergistic enhancement ratio on the exposure temperature passes through a maximum. A possible qualitative interpretation of these results is discussed.
Rassokhina
A V
AV
Medical Radiological Research Center, Russian Academy of Medical Sciences, Obninsk, Russia.
Petin
V G
VG
Zhurakovskaia
G P
GP
D004307:Dose-Response Relationship, Radiation; D011995:Recombination, Genetic / Q000502:physiology* / Q000528:radiation effects*; D012441:Saccharomyces cerevisiae / Q000502:physiology* / Q000528:radiation effects*; D013696:Temperature; D014466:Ultraviolet Rays