Adenocarcinoma of the stomach with tumor-thrombotic microangiopathy in an 11-year-old male patient.
The majority of malignancies in childhood are represented by leukemias, lymphomas or other reticuloendothelial neoplasms, tumors of the central nervous system, nephroblastomas and sarcomas. Gastrointestinal tumors represent less than 5% of pediatric neoplasms and carcinomas within this subgroup have been very rarely described, especially those arising in the stomach. In this study, we report a case of an 11-year-old boy with a signet-ring carcinoma of the stomach. The patient initially presented with respiratory symptoms which were caused by massive pulmonary lymphangiosis carcinomatosa and a peculiar microangiopathy, recently addressed as pulmonary tumor thrombotic microangiopathy. To our knowledge, this constellation has not been reported so far.
Bläker
H
H
Department of Pathology, University of Heidelberg, Germany.
Daum
R
R
Tröger
J
J
Mechtersheimer
G
G
Otto
H F
HF
D018279:Carcinoma, Signet Ring Cell / Q000150:complications*; D002648:Child; D006801:Humans; D008168:Lung / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008833:Microcirculation / Q000473:pathology; D013274:Stomach Neoplasms / Q000150:complications*; D013927:Thrombosis / Q000150:complications*; D014057:Tomography, X-Ray Computed