title: Mediators of inflammation involved in UVB erythema.
abstract: In this review, we discuss the mediators and inflammatory cells involved in UVB-induced inflammatory changes phase by phase. We especially stress the importance of IFNgamma secreted by activated CD4(+) T cells in the development of UVB erythema. We also speculate on the mechanism underlying regression of UVB erythema.
authors.affiliation: Department of Dermatology, Tohoku University School of Medicine, Seiryo-machi 1-1, Aoba-ku, Sendai, Japan. terui@mail.cc.tohoku.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Terui
authors.forename: H
authors.initials: H
authors.lastname: Tagami
mesh_terms: D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D003167:Complement Activation; D016207:Cytokines / Q000096:biosynthesis; D004890:Erythema / Q000209:etiology* / Q000276:immunology; D006801:Humans; D018836:Inflammation Mediators / Q000502:physiology*; D007371:Interferon-gamma / Q000096:biosynthesis; D009504:Neutrophils / Q000276:immunology; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis; D014466:Ultraviolet Rays / Q000009:adverse effects*
chemical_list: D016207:Cytokines; D018836:Inflammation Mediators; D014409:Tumor Necrosis Factor-alpha; D007371:Interferon-gamma