title: Two novel secoergosterols from the fungus Tylopilus plumbeoviolaceus.
abstract: Two novel secoergosterols, 3beta-hydroxy-8alpha,9alpha-oxido-8, 9-secoergosta-7,9(11),22-triene (tylopiol A) (1) and 3beta-hydroxy-8alpha,9alpha-oxido-8,9-secoergosta-7,22 -dien-12-one (tylopiol B) (2), were isolated from the fresh fruit bodies of Tylopilus plumbeoviolaceus, along with three known compounds, ergosta-7,22-dien-3beta-ol, uridine, and allitol. Their structures were elucidated by NMR techniques, including (1)H NMR, (13)C NMR, HMQC, HMBC, and MS. The structure and stereochemistry of compound 1 were demonstrated by X-ray crystallography.
authors.affiliation: Laboratory of Phytochemistry, Kunming Institute of Botany, The Chinese Academy of Sciences, Yunnan, People's Republic of China.
authors.forename: S H
authors.initials: SH
authors.lastname: Wu
authors.forename: X D
authors.initials: XD
authors.lastname: Luo
authors.forename: Y B
authors.initials: YB
authors.lastname: Ma
authors.forename: J K
authors.initials: JK
authors.lastname: Liu
authors.forename: D G
authors.initials: DG
authors.lastname: Wu
authors.forename: B
authors.initials: B
authors.lastname: Zhao
authors.forename: Y
authors.initials: Y
authors.lastname: Lu
authors.forename: Q T
authors.initials: QT
authors.lastname: Zheng
mesh_terms: D000363:Agaricales / Q000737:chemistry*; D004875:Ergosterol / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008968:Molecular Conformation; D012632:Secosteroids / Q000302:isolation & purification* / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014961:X-Ray Diffraction
chemical_list: D012632:Secosteroids; C409629:tylopiol A; C409630:tylopiol B; D004875:Ergosterol