Synthesis of some new thiazolo[3,2-a]pyridines and related heterocyclic systems.
New 2,7-disubstituted 5-amino-6,8-dicyano-2,3-dihydro-3-oxo thiazolo[3,2-a]pyridines have been prepared. Their cyclization with formamide, nitrous acid and triethylorthoformate afforded a series of polycyclic heterocycles containing condensed pyrimidine and triazine rings. Antifungal tests were also performed.
al-Thebeiti
M S
MS
Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah Almukkarramah, Saudi Arabia. althebeiti@yahoo.com
D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D000935:Antifungal Agents; D011725:Pyridines; D013844:Thiazoles