Transient appearance of antegrade conduction via an AV accessory pathway caused by atrial fibrillation in a patient with intermittent Wolff-Parkinson-White syndrome.
A 55 year old man with intermittent Wolff-Parkinson-White (WPW) syndrome had an episode of atrial fibrillation (AF) that lasted for 117 days. After interruption of the AF a Delta wave appeared that lasted for two days and then disappeared. Exercise stress and isoprenaline infusion could not reproduce the Delta wave, but after another episode of AF which lasted for seven days a persistent Delta wave appeared that lasted for six hours. In an electrophysiological study performed on a day without a Delta wave, neither antegrade nor retrograde conduction via an accessory pathway was seen, but after atrial burst pacing (at 250 ms cycle length) for 10 minutes, a Delta wave appeared lasting for 16 seconds. Atrial electrical remodelling-that is, the shortening of the atrial effective refractory period caused by AF, is a possible mechanism of the appearance of the Delta wave.
Niwano
S
S
Department of Internal Medicine, Kitasato University School of Medicine, 15-1 Kitasato 1 Sagamihara, 228-8555, Japan. niwano@med.kitasato-u.ac.jp
Kitano
Y
Y
Moriguchi
M
M
Izumi
T
T
D000284:Administration, Oral; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000188:drug therapy / Q000503:physiopathology*; D004206:Disopyramide / Q000627:therapeutic use; D004562:Electrocardiography; D006329:Heart Conduction System / Q000002:abnormalities* / Q000503:physiopathology; D006801:Humans; D007275:Injections, Intravenous; D008012:Lidocaine / Q000031:analogs & derivatives / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011342:Procainamide / Q000627:therapeutic use; D014927:Wolff-Parkinson-White Syndrome / Q000503:physiopathology*
D000889:Anti-Arrhythmia Agents; D008012:Lidocaine; C042288:pilsicainide; D004206:Disopyramide; D011342:Procainamide