title: Considerations on surgical treatment for elderly patients with intracranial aneurysms.
abstract: BACKGROUND
  The purpose of this study was to investigate why elderly patients have poorer outcomes and to determine indications for surgery in elderly patients.
  
  
  METHODS
  One hundred fifty-four patients with intracranial aneurysms admitted to the Department of Neurosurgery, Showa University School of Medicine, from 1990 through 1996 were reviewed. The patients were classified by age into three groups (young group, middle-aged group, elderly group).
  
  
  RESULTS
  Forty-four patients (28.6%) were in the elderly group (mean age, 73 years). No difference in outcome was found between middle-aged and elderly patients if patients were stratified according to clinical grade. In addition, the main factors related to unfavorable outcomes in elderly patients were infection, organ failure, aneurysm rerupture before operation, and delayed ischemic deterioration. Elderly patients were more likely to experience rebleeding and have poor outcomes.
  
  
  CONCLUSIONS
  Our results suggest that elderly patients should have early surgery. Furthermore, we found that the presence of hypertension or atherosclerosis had no significant effect on outcome. We conclude that early surgical treatment of aneurysms is indicated for elderly patients with good clinical grades in the absence of organ failure.
authors.affiliation: Department of Neurosurgery, Showa University School of Medicine, Tokyo, Japan.
authors.forename: Q
authors.initials: Q
authors.lastname: Lan
authors.forename: H
authors.initials: H
authors.lastname: Ikeda
authors.forename: H
authors.initials: H
authors.lastname: Jimbo
authors.forename: H
authors.initials: H
authors.lastname: Izumiyama
authors.forename: K
authors.initials: K
authors.lastname: Matsumoto
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D017542:Aneurysm, Ruptured / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011379:Prognosis; D013345:Subarachnoid Hemorrhage / Q000175:diagnosis / Q000401:mortality / Q000601:surgery; D015996:Survival Rate; D016896:Treatment Outcome