title: [The effect of acute external gamma-irradiation and thyroid glands dysfunction on rat reproductive system and frequency of structural mutations in somatic cells of pregnant females and their offspring].
abstract: Experimental hypofunction of thyroid gland, caused by mercazolil administration, and acute external exposure to 0.5 and 1.0 Gy of gamma-irradiation were shown to result in disturbance of reproductive function in puberal females and of estrogenreceptor interaction, in reduction of pregnancy probability, increase in pre- and postimplantation lethality of fetuses as well as in rise in the frequency of structural mutations in somatic cells of pregnant rats and their offspring.
authors.affiliation: Institute of Radiobiology, National Belarussian Academy of Science, Minsk.
authors.forename: E F
authors.initials: EF
authors.lastname: Konoplia
authors.forename: L N
authors.initials: LN
authors.lastname: Nikolaevich
authors.forename: L K
authors.initials: LK
authors.lastname: Sechko
authors.forename: L P
authors.initials: LP
authors.lastname: Glazko
mesh_terms: D000818:Animals; D005260:Female; D005720:Gamma Rays; D007037:Hypothyroidism; D018811:Maternal Exposure; D009154:Mutation / Q000528:radiation effects*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000528:radiation effects*; D051381:Rats