[Treatment of laryngeal cancer: cordectomy or crico-hyoido-epiglottopexy versus radiotherapy].
BACKGROUND
Both radiotherapy and endoscopic or open functional surgery are recognised treatments for laryngeal cancer stage I and II. A comparison between two groups of patients treated with either modality may clarify the indications for both treatments.


METHODS
Over a period of 13 years two separate series of patients were treated for laryngeal cancer (stage I and II) by either surgery (n = 72) or radiotherapy (n = 81). We have analysed and compared the two groups.


RESULTS
Statistical analyses show a better local control among patients treated with surgery, when the anterior commissure was involved (p < 0.01) or with extension of the tumour (T2). However, long-term survivals were not significantly different in the two groups. As postradiation recurrence was diagnosed at an early stage, salvage (requiring total laryngectomy in many cases) was efficient but contributed to an appreciable difference in the long-term laryngeal preservation rate between the two groups (91% after radiotherapy and 99% after surgery).


CONCLUSIONS
The treatment of laryngeal cancer must always compromise between oncological efficiency and functional preservation. With anterior commissure involvement (T1b) or more extensive disease (T2), surgery appears to be better. Therefore, preservation of perfect laryngeal function should be subordinate to oncological safety.
Bron
L
L
Service d'otorhinolaryngologie et de chirurgie cervico-faciale, CHUV, Lausanne.
Soldati
D
D
Zouhair
A
A
Ozsahin
M
M
Brossard
E
E
Monnier
P
P
Pasche
P
P
D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D003413:Cricoid Cartilage / Q000473:pathology / Q000528:radiation effects / Q000601:surgery; D004825:Epiglottis / Q000473:pathology / Q000528:radiation effects / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D006928:Hyoid Bone / Q000473:pathology / Q000528:radiation effects / Q000601:surgery; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D007828:Laryngoscopy; D009367:Neoplasm Staging; D012189:Retrospective Studies; D016896:Treatment Outcome