title: Correlates and impact on outcomes of worsening renal function in patients > or =65 years of age with heart failure.
abstract: 1.5 mg/dl. Based on the number of these factors, a patient's risk for developing worsening renal function ranged between 16% (< or =1 factor) and 53% (> or =5 factors). After adjusting for confounding effects, worsening renal function was associated with a significantly longer length of stay by 2.3 days, higher in-hospital cost by $1,758, and an increased risk of in-hospital mortality (odds ratio 2.72; 95% confidence interval 1.62 to 4.58). In conclusion, worsening renal function, an event that frequently occurs in elderly patients hospitalized with heart failure, confers a substantial burden to patients and the healthcare system and can be predicted by 6 admission characteristics.
authors.affiliation: Section of Cardiovascular Medicine, Department of Medicine, Yale University School of Medicine, New Haven, CT 06520-8025, USA. harlan.krumholz@yale.edu
authors.forename: H M
authors.initials: HM
authors.lastname: Krumholz
authors.forename: Y T
authors.initials: YT
authors.lastname: Chen
authors.forename: V
authors.initials: V
authors.lastname: Vaccarino
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: M J
authors.initials: MJ
authors.lastname: Radford
authors.forename: W D
authors.initials: WD
authors.lastname: Bradford
authors.forename: R I
authors.initials: RI
authors.lastname: Horwitz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003404:Creatinine / Q000097:blood; D005260:Female; D006333:Heart Failure / Q000503:physiopathology*; D006801:Humans; D007668:Kidney / Q000502:physiology*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged
chemical_list: D003404:Creatinine