Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery.
de Ligt
R A
RA
Leiden/Amsterdam Center for Drug Research, Division of Medicinal Chemistry, PO Box 9502, 2300RA Leiden, The Netherlands.
Kourounakis
A P
AP
IJzerman
A P
AP
D000818:Animals; D002120:Calcium Channel Agonists / Q000494:pharmacology*; D015220:Calcium Channels / Q000187:drug effects* / Q000502:physiology; D015195:Drug Design; D019204:GTP-Binding Proteins / Q000819:agonists* / Q000502:physiology; D006801:Humans; D011956:Receptors, Cell Surface / Q000819:agonists* / Q000502:physiology; D011955:Receptors, Drug / Q000819:agonists* / Q000502:physiology
D002120:Calcium Channel Agonists; D015220:Calcium Channels; D011956:Receptors, Cell Surface; D011955:Receptors, Drug; D019204:GTP-Binding Proteins