title: The use of colchicine in treatment of experimental toxoplasmosis.
abstract: Colchicine was given in 2 doses (3 and 15 micrograms/mouse) at the time of infection or 48 hours late. It proved effective in both doses, but better results were obtained with early treatment. The mortality rates were 30% & 30%, and Toxoplasma carriers among the surviving mice was 28.6% and 42.9% with high and low doses respectively. When the treatment was given 48 hours after infection, the mortality rates were 50% and 60%, Toxoplasma carriers were 40% and 50% with high and low doses respectively.
authors.affiliation: Department of Parasitology, Faculty of Medicine, Cairo University, Egypt.
authors.forename: M M
authors.initials: MM
authors.lastname: Aly
authors.forename: M A
authors.initials: MA
authors.lastname: Ismail
mesh_terms: D000818:Animals; D003078:Colchicine / Q000627:therapeutic use*; D051379:Mice; D014124:Toxoplasmosis, Animal / Q000188:drug therapy*
chemical_list: D003078:Colchicine