title: Polypropylene hollow fiber oxygenators: effect of the sorption of perfluoropolyethers.
abstract: The introduction of microporous polypropylene hollow fibers in recent years has brought considerable advances to blood oxygenators. However, lifetime and assembly problems are still unresolved. In this work we tried to rate the oxygen permeation velocity by turning the fibers more hydrophobic through the sorption of a perfluorocarbon. Fomblin HC/25, a perfluoropolyether, is well known for its low surface tension and high affinity for oxygen. Celgard X10, X20, and X30 commercial hollow fibers were tested. The hollow fibers showed high affinity for the perfluoropolyether; swelling was clearly shown. A new system for the measurement of oxygen permeation velocity was developed. The oxygen transport velocity was not significantly changed after sorption. The Celgard microporous hollow fibers impregnated with perfluoropolyether showed no water permeation after 2 months of use, reducing one of the most serious problems in the lifetime of these types of fibers.
authors.affiliation: Departamento de Físico Química, Instituto de Química, Universidade Estadual de Campinas, Campinas SP, Brazil.
authors.forename: F
authors.initials: F
authors.lastname: Cassiola
authors.forename: P K
authors.initials: PK
authors.lastname: Kiyohara
authors.forename: I
authors.initials: I
authors.lastname: Joekes
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D004867:Equipment Design; D004987:Ethers / Q000737:chemistry*; D005466:Fluorocarbons / Q000737:chemistry*; D006801:Humans; D008855:Microscopy, Electron, Scanning; D010100:Oxygen / Q000737:chemistry; D010106:Oxygenators; D010539:Permeability; D011126:Polypropylenes / Q000737:chemistry*; D016062:Porosity; D012826:Silicone Elastomers / Q000737:chemistry; D013499:Surface Properties; D013500:Surface Tension; D013997:Time Factors; D014867:Water / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible; D004987:Ethers; D005466:Fluorocarbons; D011126:Polypropylenes; D012826:Silicone Elastomers; C078113:perfluoropolyether; D014867:Water; C089227:celgard; D010100:Oxygen