Ganomycins A and B, new antimicrobial farnesyl hydroquinones from the basidiomycete Ganoderma pfeifferi.
Two new farnesyl hydroquinones named ganomycin A (1) and ganomycin B (2) were isolated from Ganoderma pfeifferi, and their structures were elucidated by spectroscopic methods. Both carboxylic acids exhibit antimicrobial activity against several Gram-positive and Gram-negative bacteria.
Mothana
R A
RA
Institute of Pharmacy, Department of Pharmaceutical Biology, Ernst-Moritz-Arndt-University, D-17487 Greifswald, Germany.
Jansen
R
R
Jülich
W D
WD
Lindequist
U
U
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001487:Basidiomycota / Q000737:chemistry*; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006873:Hydroquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D013057:Spectrum Analysis
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D006873:Hydroquinones; C408007:ganomycin A