Synthesis of biaryls by intramolecular radical aryl migration from silicon to carbon
A new method for the preparation of biaryls via intramolecular 1,5 aryl migration reaction from silicon in silyl ethers to aryl radicals is presented. Various readily available diphenylsilyl ethers can be used as substrates in this reaction. Functionalized aryl groups can also be transferred. The analogous 1,4 aryl migration reaction is less efficient.
Studer
A
Laboratorium fur Organische Chemie, Eidgenossische Technische Hochschule, Zurich. studer@org.chem.ethz.ch
Bossart
M
Vasella
T