title: [Chronic granulomatous disease accompanying a deep cervical abscess in a young child].
abstract: We report the diagnosis and otorhinological treatment of a rare case of cervical abscess in association with chronic granulomatous disease (CGD). A 19-month-old boy was admitted to our hospital's Department of Pediatrics with fever and a swollen neck. Antibiotic treatment (FMOX PIPC, and PAPM) was ineffective, so the patient was referred to our department for otorhinological treatment. A deep cervical abscess was drained using paracentesis in the Outpatient Department, but the condition did not improve. Surgery to drain the cavity was therefore performed. The wound was irrigated with oxydol, and the surgery was a success. Immunodeficiency was suspected, because of the antibiotic treatment's failure. Further examination clarified that the disease was CGD, but this diagnosis was difficult to establish. The result of the NBT test was 120%. However, some examination demonstrated that active oxygen production was impaired. The production of cytochrome b in this patient was confirmed using flow cytometric analysis. Both parents were confirmed to be carriers upon examination. The patient was therefore diagnosed as having CGD as a result of an autosomal recessive inheritance.
authors.affiliation: Department of Otolaryngology, Nantan General Hospital, Kyoto.
authors.forename: M
authors.initials: M
authors.lastname: Uchida
authors.forename: T
authors.initials: T
authors.lastname: Uno
mesh_terms: D000038:Abscess / Q000209:etiology*; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007223:Infant; D008297:Male; D009333:Neck