title: [Quantitative regularities for clinical manifestations of radiation injury in large-sized laboratory animals exposed to supralethal radiation doses Gamma-neutron and electron biological effectiveness as influenced by exposure conditions and dose distribution in the animal body].
abstract: The damaging effect of gamma-neutron radiation over a wide neutron-energy range, with average values of 0.37 and 1.2 MeV, and that of electrons with an average electron energy of 25 MeV have been compared in dogs and two monkey species exposed to a broad range of supralethal doses. An analysis of absorbed dose distribution in critical organs and systems has shown the highest effect of gamma-neutron radiation with an average neutron energy of 1.2 MeV. With severity of early clinical manifestations of damage as a criterion, electrons have appeared the most effective. The radiosensitivity of animals grew in the order as follows: dog-->M. fascicularis-->P. hamadryas.
authors.affiliation: State Research Center of Russia, Institute of Biophysics, Moscow, Russia.
authors.forename: N G
authors.initials: NG
authors.lastname: Darenskaia
authors.forename: A O
authors.initials: AO
authors.lastname: Korotkevich
authors.forename: M P
authors.initials: MP
authors.lastname: Grinev
authors.forename: I K
authors.initials: IK
authors.lastname: Sokolova
authors.forename: V I
authors.initials: VI
authors.lastname: Tsvetkov
mesh_terms: D000818:Animals; D001610:Beta Particles; D004285:Dogs; D004583:Electrons; D005720:Gamma Rays; D000882:Haplorhini; D011833:Radiation Injuries, Experimental; D011836:Radiation Tolerance; D012062:Relative Biological Effectiveness; D013045:Species Specificity