title: Changes in refraction and axial length according to the viscosity of intraocular silicone oil.
abstract: We performed this study to evaluate the changes in refraction and axial length induced by intraocular silicone oil, and to compare with various clinical parameters between 1,000 and 5,000 cSt silicone oil. The refraction length was measured with an autorefractometer, and the axial length was measured with A-scan ultrasonography. These measurements were performed before and after removal of the silicone oil, using a clear cornea technique in which the silicone oil was injected in combination with pars plana vitrectomy. The mean age of the 25 patients was 38.73 years. On average the intraocular retention after the removal of the silicone oil lasted 5.13 months, and the follow-up time following silicone oil removal was 4.37 months. The changes in refraction and axial length were 6.32 diopters and 12.02 mm, respectively. Eyes injected with 5,000 cSt (11 eyes) tended to have higher changes in the refraction (5.84 vs 6.86 diopters) and axial length (11.70 vs 12.34 mm) than did eyes injected with 1,000 cSt silicone oil (14 eyes). Statistically significant differences were shown for the changes in refraction (p = 0.010) and intraocular pressure (0.63 vs 2.00 mmHg; p = 0.006), whereas but not for the changes in axial length (p = 0.306) and visual acuity (14/100 vs 15/100; p = 0.125). Intraocular silicone oil induced changes in refraction and axial length, and these changes seemed to vary with different viscosities.
authors.affiliation: Department of Ophthalmology, Chonnam National University Medical School & Hospital, Chonnam Research Institute of Medical Sciences, Kwangju, Korea.
authors.forename: M S
authors.initials: MS
authors.lastname: Seo
authors.forename: S T
authors.initials: ST
authors.lastname: Lim
authors.forename: H D
authors.initials: HD
authors.lastname: Kim
authors.forename: B I
authors.initials: BI
authors.lastname: Park
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D012029:Refraction, Ocular / Q000502:physiology*; D012164:Retinal Diseases / Q000601:surgery; D012189:Retrospective Studies; D012827:Silicone Oils / Q000737:chemistry / Q000627:therapeutic use*; D014783:Viscosity; D014792:Visual Acuity; D014821:Vitrectomy; D014822:Vitreous Body
chemical_list: D012827:Silicone Oils