title: [The nature of SOS response in E. coli K-12 (uvrA) cells exposed to the different ultraviolet doses].
abstract: The kinetic and dose dependencies of the SOS-induction in E. coli (uvrA) cells exposed to UV light were investigated. Below 2 J/m2 the rate of the SOS-induction increased with dose. The maximal level of the SOS-response was proportional to the UV dose. Pyrimidine dimers were necessary for the induction. In the dose range 2-10 J/m2 the rate of the SOS-induction decreased with dose. The dose-response curve was non-linear. Pyrimidine dimers were not required for the induction. The nature of the molecular events leading to the SOS-induction at low and high doses was discussed.
authors.affiliation: Joint Institute for Nuclear Research, Dubna, Moscow Oblast, Russia. komova@cv.jinr.ru
authors.forename: O V
authors.initials: OV
authors.lastname: Komova
authors.forename: E S
authors.initials: ES
authors.lastname: Kandiano
authors.forename: G
authors.initials: G
authors.lastname: Malavia
mesh_terms: D004926:Escherichia coli / Q000235:genetics* / Q000528:radiation effects*; D011829:Radiation Dosage; D013014:SOS Response, Genetics / Q000528:radiation effects*; D014466:Ultraviolet Rays