title: How well does the Oxfordshire community stroke project classification predict the site and size of the infarct on brain imaging?
abstract: OBJECTIVE
  The Oxfordshire Community Stroke Project (OCSP) classification is a simple clinical scheme for subdividing first ever acute stroke. Several small studies have shown that when an infarct is visible on CT or MRI, the classification predicts its site in about three quarters of patients. The aim was to further investigate this relation in a much larger cohort of patients in hospital with ischaemic stroke.
  
  
  METHODS
  Between 1994 and 1997, inpatients and outpatients with ischaemic stroke were assessed by one of several stroke physicians who noted the OCSP classification. A neuroradiologist classified the site and extent of recent infarction on CT or MRI.
  
  
  RESULTS
  Of 1012 patients with ischaemic stroke, 655 (65%) had recent visible infarcts. These radiological lesions were appropriate to the clinical classification in 69/87 (79%) patients with a total anterior circulation syndrome, 213/298 (71%) with a partial anterior circulation syndrome, 105/144 (73%) with a lacunar syndrome, and 105/126 (83%) with a posterior circulation syndrome. Overall, 75% of patients with visible infarcts were correctly classified clinically. If patients without a visible infarct did have an appropriate lesion in the brain (best case), the classification would have correctly predicted its site and size in 849/1012 (84%) patients, compared with only 492/1012 (49%) in the worst case scenario.
  
  
  CONCLUSIONS
  The OCSP classification predicted the site of infarct in three quarters of patients. When an infarct is visible on brain imaging, the site of the infarct should guide the use of further investigations, but if an infarct is not seen, the OCSP classification could be used to predict its likely size and site.
authors.affiliation: Neurosciences Trials Unit, Department of Clinical Neurosciences, Western General Hospital, Edinburgh EH4 2XU, UK.
authors.forename: G E
authors.initials: GE
authors.lastname: Mead
authors.forename: S C
authors.initials: SC
authors.lastname: Lewis
authors.forename: J M
authors.initials: JM
authors.lastname: Wardlaw
authors.forename: M S
authors.initials: MS
authors.lastname: Dennis
authors.forename: C P
authors.initials: CP
authors.lastname: Warlow
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology*; D002544:Cerebral Infarction / Q000145:classification* / Q000175:diagnosis; D015331:Cohort Studies; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D020521:Stroke / Q000145:classification* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed