[Alpha herpesvirus infections in AIDS patients].
Alpha-herpesvirus infections by herpes simplex virus and varicella-zoster virus among HIV-infected patients were summarized. These infections were occurred in a high frequency and shown to be extensive lesions, prolonged virus excretion from the lesions, generalized infection, and uncommon diseases as compared these of with immunocompetent patients. Acyclovir-resistant viruses appeared. These evidences supplied the profound understanding of the pathogenesis and new subjects in the field of herpesvirus infection. Recent introduction of HAART against HIV and the appropriate use of anti-herpesvirus drugs, however, reduced the development of severe infection, and provided successful treatment, respectively.
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Laboratory of Pathology, AIDS Research Center.
D017088:AIDS-Related Opportunistic Infections; D018138:Alphaherpesvirinae; D006566:Herpesviridae Infections / Q000635:transmission*; D006801:Humans