[The use of ion-selective field transistors (ISFT) with photopolymerizable polyurethane membranes in nephrology for determination of potassium concentration (activity)].
The applicability is examined of ion selective field transistors with photocurable polyurethane membranes to control of the electrolytic composition of dialyzing solutions used in artificial kidney apparatus, and also of plasma in patient treated by chronic hemodialysis. The short- and long-time characteristics of the efficiency of K(+)-selective field transistors in continuous contact with solutions. Comparative testing of such transistors and other sensing systems is made. It is demonstrated that a sufficient reliability of measurements in the range of physiological concentrations in combination with low cost provide the possibility of using K(+)-selective field transistors for monitoring of the potassium concentration both in dialyzing solutions and plasma in patients on chronic hemodialysis treatment.
Abramova
N Iu
NIu
Pavlov State Medical University, St. Petersburg, Russia.
Borisov
Iu A
IuA
Bratov
A V
AV
Gavrilenkov
P V
PV
Dominguez
K
K
Spiridonov
V N
VN
Suglobova
E D
ED
D006801:Humans; D007688:Kidneys, Artificial; D008567:Membranes, Artificial; D011140:Polyurethanes; D011188:Potassium / Q000032:analysis*; D006435:Renal Dialysis / Q000295:instrumentation; D014173:Transistors, Electronic
D008567:Membranes, Artificial; D011140:Polyurethanes; D011188:Potassium