[Recent donation and clinical results of homograft tissue].
Between August 1995 and July 1999, we have experienced 14 donors for allografts (mean age: 39.8 +/- 15.8, M/F = 10/4, mean warm ischemic time: 359 minutes). Donated tissues were included 12 aortic valves and 12 pulmonary valves, respectively. Since February 1994, clinical diagnoses of 14 patients included 7 congenital heart disease, 5 infective heart disease, 1 artificial graft infection, and 1 thrombosed valve. There was no graft-transmitted disease. In congenital heart disease, 3 patients (HLHS: 1, Truncus: 1, TOF + PA: 1) died (early mortality, 42%) and 1 with TGA had residual conduit stenosis. However, in infective heart disease, all patients survived without recurrent infection and did not need reoperation (early mortality, 0%). Our clinical results of homograft implantation for infective heart disease were excellent, but more careful consideration will be needed for congenital heart disease in neonates and/or patients with poor preoperative condition.
Suematsu
Y
Y
Department of Cardiothoracic Surgery, University of Tokyo, Japan.
Takamoto
S
S
Murakami
A
A
Nakajima
J
J
Ono
M
M
Murakami
T
T
Maeda
K
K
Kotsuka
Y
Y
Yoneda
N
N
D000293:Adolescent; D000328:Adult; D000368:Aged; D001808:Blood Vessels / Q000637:transplantation*; D002648:Child; D005260:Female; D006330:Heart Defects, Congenital / Q000601:surgery; D006351:Heart Valves / Q000637:transplantation*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007564:Japan; D008297:Male; D008875:Middle Aged; D014019:Tissue Donors / Q000706:statistics & numerical data*; D014184:Transplantation, Homologous