title: [A case of fixed sporotrichosis with recurred in a child following itraconazole treatment].
abstract: We report a case of fixed sporotrichosis in a 2-year-old girl who showed a reddish nodule on her left cheek for 1 year without trauma. Fungi flora-Y staining showed fungal elements from the exudate onthe erosion of this nodule. Sporothrix schenckii was isolated from a culture of the fungus taken from the biopsy specimen. Treatment with itraconazole 4.5 mg/kg/day for 16 weeks resulted in an atrophic scar after 2.1 mg/kg/day for 8 weeks without side effects. Six months later, her eruption recurred and wastreated with potassium iodide for 21 weeks with complete resolution. During the 1 year follow up period, there was no recurrence. Six cases of sporotrichosis in children including ours have been reported in Japan. Each case showed complete resolution and no recurrence. However, careful follow-up is believed to be necessary based on our case.
authors.affiliation: Department of Dermatology, Shimizu City Hospital, 1231 Miyakami, Shimizu-shi, Shizuoka 424-8636, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: M
authors.initials: M
authors.lastname: Sugiura
authors.forename: Y
authors.initials: Y
authors.lastname: Hata
authors.forename: W
authors.initials: W
authors.lastname: Naka
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D005148:Facial Dermatoses / Q000188:drug therapy*; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D012008:Recurrence; D013174:Sporotrichosis / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole