Chemoselective C-H oxidation of alcohols to carbonyl compounds with iodosobenzene catalyzed by (salen)chromium complex
Primary and secondary alcohols with benzylically and allylically activated C-H bonds are chemoselectively oxidized to the corresponding carbonyl compounds by the (salen)Cr(III) complex I as the catalyst and iodosobenzene as the oxygen source; the oxidizing species is the Cr(V) oxo complex. Allylic alcohols with fully substituted double bonds give appreciable amounts of epoxides besides the C-H oxidation products enones, while saturated alcohols are less readily oxidized.
Adam
W
Institute of Organic Chemistry, University of Wurzburg, Germany. adam@chemie.uni-wuerzburg.de
Gelalcha
FG
Saha-Moller
CR
Stegmann
VR