title: [Nutritional deficiency and Alzheimer's disease: how to identify and prevent].
abstract: Weight loss is a very common problem for patients with Alzheimer's Disease (AD), whether they live at home or in long-term care facilities. At any rate it depends on an imbalance between energy expenditure and intake. Though in the initial phases of the illness, the weight loss might be caused by socio-environmental and psychological factors and reduced autonomy, in the following stages it depends on Adversive Feeding Behaviours (AFBs). The AFBs invariably lead to protein, fat and sugar deficits as well as a vitamin deficit which presents a positive correlation with the cognitive performance level and negatively affects the course of the disease. Thus it is important to identify AFBs (Blandford Scale) as soon as possible, especially when they can be treated. Furthermore it is very important to recognise weight loss immediately and identify a possible malnutrition state, using investigative methods which allow for follow-up monitoring (Mini Nutritional Assessment). Pharmacological therapy of cognitive deficit and AFBs together with possible contemporary conditions (depression) and intervention on the nutrition, will be useful to avoid a deficiency state and the consequent negative repercussion on the disease.
authors.affiliation: Cattedra di Gerontologia e Geriatria, Università La Sapienza, Roma.
authors.forename: P
authors.initials: P
authors.lastname: Cicconetti
authors.forename: A
authors.initials: A
authors.lastname: Fionda
authors.forename: C
authors.initials: C
authors.lastname: Bauco
authors.forename: M
authors.initials: M
authors.lastname: Migliori
authors.forename: V
authors.initials: V
authors.lastname: Marigliano
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000150:complications* / Q000175:diagnosis; D001361:Avitaminosis / Q000150:complications / Q000175:diagnosis / Q000517:prevention & control; D003677:Deficiency Diseases / Q000150:complications* / Q000175:diagnosis / Q000517:prevention & control; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D015431:Weight Loss