Serendipitous synthesis of novel dehydro- and dechloro-pseudomycin B (PSB) derivatives.
The syntheses and preliminary investigation of antifungal activities of two dehydro PSB derivatives 8 and 10 as well as one 3-imido-9-dechloro PSB analogue 13 are described.
Zhang
Y
Y
Lilly Research Laboratories, a Division of Eli Lilly and Company, Indianapolis, IN 46285, USA.
Boyer
R
R
Sun
X
X
Paschal
J
J
Chen
S H
SH
D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D002713:Chlorine / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D010456:Peptides, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D014867:Water / Q000737:chemistry
C409451:3-imido-9-dechloropseudomycin B; D000935:Antifungal Agents; D010456:Peptides, Cyclic; D014867:Water; D002713:Chlorine