Melanotic differentiation in dysembryoplastic neuroepithelial tumor.
Dysembryoplastic neuroepithelial tumor (DNT) is an uncommon intracranial tumor which is usually encountered in patients with medically intractable complex partial seizures of temporal lobe origin. Melanotic differentiation in a DNT has not been reported previously. Herewith we report a case of DNT with unique melanotic differentiation in a 23-year-old female who presented with medically intractable epilepsy. She underwent craniotomy and tumor decompression with a good outcome. We present the histopathological features of DNT with melanotic differentiation and discuss its prognostic significance.
Elizabeth
J
J
Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Bhaskara
R M
RM
Radhakrishnan
V V
VV
Radhakrishnan
K
K
Thomas
S V
SV
D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D017029:Epilepsy, Complex Partial / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D018242:Neuroectodermal Tumors, Primitive / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D011612:Psychosurgery; D013702:Temporal Lobe / Q000473:pathology* / Q000601:surgery