title: Focal nodular hyperplasia contiguous with an echinococcal cyst.
abstract: We report the first case of an Echinococcal cyst and focal nodular hyperplasia, two usually isolated hepatic lesions, in direct contiguity. The patient presented with right upper quadrant pain and subsequent imaging studies found a cystic and solid lesion. These studies suggested that this lesion was an hepatic adenoma, which had bled forming a hematoma. Pathological examination of the surgical resection showed Echinococcus multilocularis with contiguous focal nodular hyperplasia. Because focal nodular hyperplasia is a benign hepatic lesion the etiology of which is thought to be abnormal arterial blood flow, we postulate that the parasitic hepatic infection by E. multilocularis may have incited the formation of this contiguous hepatic lesion.
authors.affiliation: Department of Pathology, Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, Philadelphia, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Komisarof
authors.forename: K
authors.initials: K
authors.lastname: Olthoff
authors.forename: E S
authors.initials: ES
authors.lastname: Siegelman
authors.forename: T J
authors.initials: TJ
authors.lastname: Lawton
authors.forename: E E
authors.initials: EE
authors.lastname: Furth
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004444:Echinococcosis, Hepatic / Q000473:pathology*; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology