[Changes in the cerebral microcirculatory bed under molybdenum exposure].
Histochemical study of brain hemisphere hemo-microcirculatory bed in rats treated with large doses of molybdenum demonstrated significant 30-55% narrowing of capillary diameter as compared to that in normal animals. This constriction is likely to cause capillary trophic insufficiency syndrome that is important in pathogenetic mechanisms of molybdenum-induced toxicosis.
Markarian
N V
NV
Laboratory of Histochemistry and Morphology, L.A. Orbeli Institute of Physiology, National Academy of Sciences of Armenia, Yerevan.
Meliksetian
I B
IB
D000818:Animals; D001160:Arterioles / Q000187:drug effects / Q000473:pathology; D001921:Brain / Q000098:blood supply* / Q000187:drug effects / Q000473:pathology; D002196:Capillaries / Q000187:drug effects / Q000473:pathology; D004785:Environmental Pollutants / Q000633:toxicity*; D006651:Histocytochemistry; D008833:Microcirculation / Q000187:drug effects; D008982:Molybdenum / Q000633:toxicity*; D051381:Rats
D004785:Environmental Pollutants; D008982:Molybdenum