title: Fat redistribution in HIV disease.
abstract: BACKGROUND
  Abnormal distributions of body fat have been reported in association with HIV infection, including cases of both regional loss and gain of fat.
  
  
  OBJECTIVE
  We describe the spectrum of abnormal fat distribution in HIV-positive patients.
  
  
  METHODS
  Patients were included if they demonstrated a lack of subcutaneous fat in the cheeks in the absence of generalized wasting. Patients were examined fully and photographed, and medical records were reviewed.
  
  
  RESULTS
  Fourteen patients were seen. Further abnormalities of body fat distribution were noted in all patients. We found a consistent pattern of fat loss in the cheeks, temples, and extremities as well as fat gain over the neck, upper back, mastoid processes, chest, and visceral abdomen.
  
  
  CONCLUSIONS
  A consistent syndrome of body fat redistribution is seen in HIV-positive patients. A characteristic pattern of fat loss in the cheeks may serve as a specific marker of HIV-related fat redistribution.
authors.affiliation: Department of Dermatology, University of California San Francisco, San Francisco General Hospital,94110, USA.
authors.forename: G E
authors.initials: GE
authors.lastname: Rodwell
authors.forename: T A
authors.initials: TA
authors.lastname: Maurer
authors.forename: T G
authors.initials: TG
authors.lastname: Berger
mesh_terms: D000273:Adipose Tissue / Q000503:physiopathology*; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D001786:Blood Glucose / Q000032:analysis; D015658:HIV Infections / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D006679:HIV Seropositivity / Q000503:physiopathology; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged
chemical_list: D019380:Anti-HIV Agents; D001786:Blood Glucose; D008055:Lipids