title: Wavelet analysis and time-frequency distributions of the body surface ECG before and after angioplasty.
abstract: In a pilot study, electrocardiographic (ECG) recordings of patients with left and right coronary stenosis taken before and after angioplasty were analyzed using the continuous wavelet transform. Time-frequency distributions were obtained for different leads in order to examine the dynamics of the QRS-spectrum and establish features specific of ischemia in the time-frequency domain. We found relevant changes in the mid-frequency range, reflecting the ECG's response to percutaneous transluminal coronary angioplasty (PTCA). The changes appeared in ECG leads close to ischemic zones of the myocardium. Time-frequency distributions of the ECG during the QRS may thus become another electrocardiographic indicator of ischemia, alternative to ST-level in standard ECG or body surface mapping. The paper demonstrates the ability of the continuous wavelet transform to detect short lasting events of low amplitude superimposed on large signal deflections.
authors.affiliation: Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA. bgramat@bme.jhu.edu
authors.forename: B
authors.initials: B
authors.lastname: Gramatikov
authors.forename: J
authors.initials: J
authors.lastname: Brinker
authors.forename: S
authors.initials: S
authors.lastname: Yi-chun
authors.forename: N V
authors.initials: NV
authors.lastname: Thakor
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D002637:Chest Pain / Q000503:physiopathology* / Q000601:surgery; D003327:Coronary Disease / Q000503:physiopathology* / Q000601:surgery; D004562:Electrocardiography; D004594:Electrophysiology; D006801:Humans; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000503:physiopathology; D010865:Pilot Projects; D013997:Time Factors