[A chamber for evaluating the free choice by laboratory rats and mice of a space containing tobacco smoke].
An original experimental setup has been designed that allows evaluation of the free preference of space containing tobacco smoke by small laboratory animals. For the laboratory mice (C57B1/6 and BALB/c) and rats (MNRA and MR) placed every day into this box, no emotional-stress reaction (ESR) caused by the environment novelty was observed on the 19th day of experiment. A difference in the free preference of space containing tobacco smoke was observed between inbred animals with active and passive ESR phenotypes.
Seredenin
S B
SB
Laboratory of Pharmacogenetics, Russian Academy of Medical Sciences, Moscow, Russia.
Zhukov
V N
VN
Miramedova
M G
MG
Badyshtov
B A
BA
Kolotilinskaia
N V
NV
Rybina
I V
IV
Nadorov
S A
SA
D000818:Animals; D000830:Animals, Laboratory / Q000502:physiology*; D014151:Anti-Anxiety Agents / Q000494:pharmacology; D002755:Choice Behavior / Q000187:drug effects / Q000502:physiology*; D003975:Diazepam / Q000494:pharmacology; D004867:Equipment Design; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D051381:Rats; D011919:Rats, Inbred Strains; D012107:Research Design; D012906:Smoke / Q000009:adverse effects*; D013037:Spatial Behavior / Q000187:drug effects / Q000502:physiology*
D014151:Anti-Anxiety Agents; D012906:Smoke; D003975:Diazepam