Prolactin secretion and the immune system.
Prolactin receptors were identified on the membranes of lymphocytes have been demonstrated to secrete prolactin. The decrease, as well as the increase of the prolactin level in the plasma are responsible for immune disorders. Prolactin dysfunction has been described in some autoimmune diseases, such as systemic lupus erythematosus, immune arthritis, uveitis, experimental allergic encephalomyelitis and thyroid disease. The normal prolactin secretion is trophic for the lymphocytes, while the high and also the low levels of prolactin may play an immunosuppressive role.
Luca
I C
IC
Disciplina de Histologie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
D000818:Animals; D005260:Female; D006801:Humans; D007107:Immune System / Q000502:physiology*; D007154:Immune System Diseases / Q000503:physiopathology; D011388:Prolactin / Q000378:metabolism*; D011981:Receptors, Prolactin / Q000502:physiology
D011981:Receptors, Prolactin; D011388:Prolactin