title: [3-dimensional magnetic resonance angiography in apnea with the rapid infusion of a paramagnetic contrast medium in studying the thoracic aorta].
abstract: BACKGROUND
  We investigated the diagnostic accuracy of gadolinium-enhanced 3D MRA in the assessment of thoracic aortic diseases.
  
  
  METHODS
  Thirty-eight patients with diagnosed or suspected conditions of thoracic aorta were examined with contrast-enhanced MRA. All the examinations were performed with a 1.5 T superconductive magnet acquiring breath-hold 3D fast Gradient-Echo (GE) sequences (TR = 5.9 ms; TE = 1.2 ms; FA = 45 degrees; FOV = 48 cm; thickness = 2-2.5 mm; locs = 30-32; TA = 22-24 s; MA = 512) on the coronal plane. The contrast agent was injected bolus after a bolus-test to evaluate circulation time.
  
  
  RESULTS
  Three-dimensional gadolinium-enhanced MRA permitted to correctly diagnose aneurysm in 18 patients, dissection in 13 patients and coarctation in 3 patients. In the former the size and extent of the aneurysmal lumen and its relationship to aortic side branches was demonstrated. As for dissections we evaluated the following parameters: 1) type; 2) presence of intimal flap; 3) thrombosis of the false lumen; 4) dilatation of the aorta; 5) assessment of great vessel origins. MRA data were correlated with those of biplane transesophageal esophageal echocardiography, conventional MRI and spiral CT. In the three patients with aortic coarctation the site of coarctation was correctly identified, the degree of aortic narrowing evaluated and the collateral vessels demonstrated.
  
  
  CONCLUSIONS
  In our opinion contrast-enhanced three-dimensional MR angiography should be the screening technique of choice in the evaluation of thoracic aorta thanks to its low invasiveness, short acquisition time, large field of view and morphologic resolution. ECG gating is not needed. Limitations are found in the study of wall and periaortic region which are better evaluated with conventional MR imaging.
authors.affiliation: Istituto di Radiologia Università degli Studi, L'Aquila, AQ.
authors.forename: E
authors.initials: E
authors.lastname: Di Cesare
authors.forename: A V
authors.initials: AV
authors.lastname: Giordano
authors.forename: G
authors.initials: G
authors.lastname: Cerone
authors.forename: A
authors.initials: A
authors.lastname: Splendiani
authors.forename: O
authors.initials: O
authors.lastname: Michelini
authors.forename: C
authors.initials: C
authors.lastname: Masciocchi
mesh_terms: D000328:Adult; D000368:Aged; D000784:Aortic Dissection / Q000175:diagnosis; D001013:Aorta, Thoracic / Q000473:pathology*; D017545:Aortic Aneurysm, Thoracic / Q000175:diagnosis; D001017:Aortic Coarctation / Q000175:diagnosis; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D005682:Gadolinium / Q000008:administration & dosage*; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged
chemical_list: D003287:Contrast Media; D005682:Gadolinium