title: Comparison of electrodessication with CO2 laser for the treatment of actinic cheilitis.
abstract: BACKGROUND
  Actinic cheilitis is a common premalignant condition that is most often treated with destructive therapy. The most effective technique is usually considered to be CO2 laser resurfacing. Little has been written on the use of electrodessication for this condition.
  
  
  OBJECTIVE
  We designed a study to compare these two treatment modalities for the treatment of biopsy-confirmed actinic cheilitis.
  
  
  METHODS
  A random half of the lower lip was treated with electrodessication. The contralateral half was then treated with CO2 laser. Healing time, subjective pain during healing, and clinical outcome at 3 months was compared.
  
  
  RESULTS
  The side treated with electrodessication took significantly longer to heal than the side treated with the CO2 laser (23 versus 14 days, P <.001). There was no difference in subjective pain or clinical appearance at 3 months.
  
  
  CONCLUSIONS
  Although the healing time is longer with electrodessication, this modality represents an inexpensive practical ablative treatment method for actinic cheilitis.
authors.affiliation: Dermatology Service, Ft. Stewart, Georgia,; Dermatology Service, Ft. Riley, Kansas, USA. rlaws@bigfoot.com
authors.forename: R A
authors.initials: RA
authors.lastname: Laws
authors.forename: J L
authors.initials: JL
authors.lastname: Wilde
authors.forename: W J
authors.initials: WJ
authors.lastname: Grabski
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002613:Cheilitis / Q000209:etiology / Q000601:surgery*; D004598:Electrosurgery; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008048:Lip Neoplasms / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000601:surgery; D013472:Sunlight / Q000009:adverse effects*; D014945:Wound Healing