title: Effect of Ocimum sanctum fixed oil on vascular permeability and leucocytes migration.
abstract: Ocimum sanctum fixed oil significantly inhibited the rise in protein concentration and dye leakage in peritoneal fluid in experimentally induced peritoneal inflammation in mice. In carrageenan-induced pleurisy in rats, the fixed oil showed significant inhibition of leucocytes migration in the pleural exudate. The results suggest that the fixed oil can inhibit enhancement of the vascular/capillary permability and leucocyte migration following inflammatory stimulus.
authors.affiliation: College of Pharmacy (University of Delhi), New Delhi, India.
authors.forename: S
authors.initials: S
authors.lastname: Singh
authors.forename: D K
authors.initials: DK
authors.lastname: Majumdar
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D002199:Capillary Permeability / Q000187:drug effects*; D002465:Cell Movement / Q000187:drug effects; D007962:Leukocytes / Q000187:drug effects / Q000502:physiology; D051379:Mice; D018649:Ocimum basilicum; D010538:Peritonitis / Q000188:drug therapy; D010938:Plant Oils / Q000494:pharmacology*; D051381:Rats
chemical_list: D000893:Anti-Inflammatory Agents; D010938:Plant Oils; C080118:ocimum oil