title: [Reconstruction of the ossicular chain with titanium implants. Results of a multicenter study].
abstract: BACKGROUND
  For decades, oto-surgeons have been trying to find suitable alloplastic materials for replacing ossicles in the case of morphological and functional disorders in the middle ear. The focus of attention has been on tissue tolerance and functionality.
  
  
  METHODS
  A retrospective analysis of the implantation of titanium prostheses is presented (Type "Duesseldorf", Heinz Kurz GmbH, Dusslingen, Germany) in 528 patients operated in 14 ENT hospitals. The hospitals involved are ENT hospitals with different fields of specialization presenting a representative cross-section of surgical ENT treatment. Evaluated were healing results, hearing gain and surgical handling of the implants.
  
  
  RESULTS
  Despite pathological middle ear conditions, the tissue-implant healing rate was very high. In 4.4% of the patients the implants were rejected. In the case of partial ossicular reconstruction, an average hearing gain between 10 and 20 dB was achieved. Total reconstruction of the ossicular chain showed even better audiological results (15 to 20 dB on average).
  
  
  CONCLUSIONS
  Due to the good morphological and functional results achieved, titanium implants have proven their worth for middle ear micro-surgery. Their advantages are their light weight and delicate structure, facilitating very good micro-surgical handling. It is advisable to place a thin layer of cartilage between the prosthesis headplate and the tympanic membrane. In this manner, the number of material extrusions can be safely reduced, however, extrusions cannot completely be avoided.
authors.affiliation: HNO-Klinik, St. Salvator-Krankenhaus, Halberstadt. begall@hno.salvator-kh.de
authors.forename: K
authors.initials: K
authors.lastname: Begall
authors.forename: H
authors.initials: H
authors.lastname: Zimmermann
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006309:Hearing / Q000502:physiology*; D006320:Hearing Tests; D006801:Humans; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D009998:Ossicular Prosthesis; D019933:Ossicular Replacement; D011475:Prosthesis Failure; D012189:Retrospective Studies; D013997:Time Factors; D014025:Titanium
chemical_list: D014025:Titanium