title: Spatio-temporal registration of the expression patterns of Drosophila segmentation genes.
abstract: The application of image registration techniques resulted in the construction of an integrated atlas of Drosophila segmentation gene expression in both space and time. The registration method was based on a quadratic spline approximation with flexible knots. A classifier for automatic attribution of an embryo to one of the temporal classes according to its gene expression pattern was developed.)
authors.affiliation: Institute of High Performance Computing and Data Bases, St.Petersburg, Russia. reinitz@kruppel.molbio.mssm.edu
authors.forename: E M
authors.initials: EM
authors.lastname: Myasnikova
authors.forename: D
authors.initials: D
authors.lastname: Kosman
authors.forename: J
authors.initials: J
authors.lastname: Reinitz
authors.forename: M G
authors.initials: MG
authors.lastname: Samsonova
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D004330:Drosophila / Q000235:genetics*; D004625:Embryo, Nonmammalian; D015870:Gene Expression; D017344:Genes, Insect; D015233:Models, Statistical; D009693:Nucleic Acid Hybridization; D012984:Software; D013223:Statistics as Topic; D013997:Time Factors