A new method for quality control of zinc pyritione pharmaceutical and cosmetic forms.
A simple high-performance liquid chromatographic (HPLC) method was developed to determine zinc pyritione in pharmaceutical and cosmetic products. Reversed-phase chromatography was conducted using a C18 column with an isocratic mobile phase consisting of a suitable mixture of methanol, acetonitrile, and water (30:2.5:20). The effluent was monitored on a ultraviolet (UV) detector at 243 nm. The method was validated following International Conference on Harmonisation (ICH) suggestions and proved accurate, precise, and specific.
Zubata
P
P
Cátedra de Control de Calidad de Medicamentos, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
Ceresole
R
R
Pizzorno
M T
MT
D002851:Chromatography, High Pressure Liquid; D003358:Cosmetics / Q000737:chemistry* / Q000592:standards; D004364:Pharmaceutical Preparations / Q000737:chemistry* / Q000592:standards; D011786:Quality Control; D012680:Sensitivity and Specificity; D017967:Zinc Compounds / Q000032:analysis*
D003358:Cosmetics; D004364:Pharmaceutical Preparations; D017967:Zinc Compounds