title: qBrain-2, a POU domain gene expressed in quail embryos.
abstract: We isolated a quail class III POU domain gene, qBrain-2, which was cloned from a cDNA library of E5 embryos. Northern blot and in situ hybridization analyses showed that qBrain-2 was expressed in developing central nervous system and adult brain. Moreover, qBrain-2 transcripts showed a dynamic distribution in embryonic central nervous system. Its transcripts were dominantly detected in the ventricular zone of the developing brain and spinal cord, but rarely in the differentiated region of mantle zone as well as the non-neuronal roof plate and floor plate. This suggests that qBrain-2 is involved in proliferation and differentiation of the neuroepithelial cells of quail central nervous system.
authors.affiliation: Laboratory of Visual Information Processing, Institute of Biophysics, Chinese Academy of Sciences, 15 Da Tun Road, Chaoyang District, Beijing, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Liu
authors.forename: J
authors.initials: J
authors.lastname: Xue
authors.forename: W
authors.initials: W
authors.lastname: Zhang
authors.forename: D
authors.initials: D
authors.lastname: Fu
authors.forename: R
authors.initials: R
authors.lastname: He
authors.forename: Z
authors.initials: Z
authors.lastname: Xue
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D001921:Brain / Q000196:embryology* / Q000378:metabolism; D003001:Cloning, Molecular; D003370:Coturnix / Q000196:embryology / Q000235:genetics*; D018076:DNA, Complementary / Q000737:chemistry / Q000235:genetics; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000235:genetics*; D015870:Gene Expression; D008969:Molecular Sequence Data; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000235:genetics*; D050809:POU Domain Factors; D012333:RNA, Messenger / Q000032:analysis; D016415:Sequence Alignment; D013116:Spinal Cord / Q000196:embryology / Q000378:metabolism
chemical_list: D018076:DNA, Complementary; D004268:DNA-Binding Proteins; D009419:Nerve Tissue Proteins; D050809:POU Domain Factors; D012333:RNA, Messenger; C074066:Pou3f2 protein, mouse