[Relationship between electronic structure and eadioprotective activity of some indazoles].
Quantum chemical MNDO study of electronic structure for 29 indazoles has been performed. Statistically significant quantitative relation between some characteristics obtained and radioprotective activity was found out. Indazole structures which data predicted for radioprotective activity (survival, %) are on 50% level or more are proposed.
Sokolov
I U
IU
Institute of Bioorganic Chemistry of National Academy of Sciences, Minsk. lando@ns.iboch.ac.by
D007191:Indazoles / Q000737:chemistry*; D015394:Molecular Structure; D011837:Radiation-Protective Agents / Q000737:chemistry*; D012044:Regression Analysis; D013329:Structure-Activity Relationship
D007191:Indazoles; D011837:Radiation-Protective Agents