title: [Medulloblastomas: clinical, epidemiological and pathological findings in 28 cases].
abstract: We report the clinical, epidemiological and pathological findings of 28 patients with medulloblastoma: 22 were male; age ranged from 1 to 50 years, with a mean of 15 years. The most frequent symptoms and signs were headache (64%) and vomiting (64%). Only one patient showed a desmoplastic medulloblastoma variant, the others showed classical medulloblastomas. Regarding treatment, most patients were submitted to total resection (n=10) or partial tumorectomy (n=7). A low rate of tumoral recurrence was observed, occurring in 21% of the patients (n=6) after 4 years of follow-up. Chemotherapy seemed to contribute to a lower recurrence rate amongst our patients. Our findings are similar to those reported in literature, thus helping to understand the biological behavior of this type of tumor.
authors.affiliation: Serviço de Anatomia Patológica, Hospital de Clínicas (HC), Universidade Federal do Paraná (UFPR).
authors.forename: J S
authors.initials: JS
authors.lastname: Reis Filho
authors.forename: E L
authors.initials: EL
authors.lastname: Gasparetto
authors.forename: L N
authors.initials: LN
authors.lastname: Faoro
authors.forename: J C
authors.initials: JC
authors.lastname: Araújo
authors.forename: L F
authors.initials: LF
authors.lastname: Torres
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D002528:Cerebellar Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008527:Medulloblastoma / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D017678:Sex Distribution