Teaching tumour suppressors new tricks.
Examination of the tumour suppressor adenomatous polyposis coli (APC) has shown that it may be multifunctional. Recent work has demonstrated dynamic interactions of APC with the microtubule cytoskeleton, supporting the idea that APC has an important function in cell migration.
McCartney
B M
BM
Peifer
M
M
D025601:Adenomatous Polyposis Coli Protein; D002465:Cell Movement / Q000502:physiology; D003598:Cytoskeletal Proteins / Q000502:physiology*; D016147:Genes, Tumor Suppressor / Q000502:physiology*; D008870:Microtubules / Q000502:physiology*; D009363:Neoplasm Proteins / Q000502:physiology
D025601:Adenomatous Polyposis Coli Protein; D003598:Cytoskeletal Proteins; D009363:Neoplasm Proteins