Detection of high risk pregnancies with relation to ABO haemolytic disease of newborn.
IgM and IgG anti A and anti B antibody status of 100 antenatal O group mothers (who had non O group husbands) were studied. Of these, 3 mothers had an IgM anti A antibody levels ranging from 1:512 to 1:2048 and IgG ranging from 1:1204 to 1:2048, IgM anti B ranging from 1:128 to 1:512 and IgG anti B ranging from 1:256 to 1:512. All these mothers had A + ve children and all these children suffered from ABO haemolytic disease of newborn (HDN). A 4th mother had an IgM anti A titre of 1:64 and IgG anti A titre of 1:16. The titre of IgM anti B in this mother was 1:512 and that of IgG 1:1024. The child was A + ve and did not suffer from ABO haemolytic disease of newborn.
Usha
K K
KK
Blood Bank Medical College, Trivandrum, Kerala.
Sulochana
P V
PV
D000017:ABO Blood-Group System; D000328:Adult; D001787:Blood Group Incompatibility / Q000097:blood / Q000175:diagnosis*; D004899:Erythroblastosis, Fetal / Q000097:blood / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007518:Isoantibodies / Q000097:blood; D008297:Male; D011247:Pregnancy; D018566:Pregnancy, High-Risk
D000017:ABO Blood-Group System; D007518:Isoantibodies