title: Effect of perifoveal tissue dissection in the management of acute idiopathic full-thickness macular holes.
abstract: OBJECTIVE
  To evaluate the efficacy of perifoveal tissue dissection (PTD) on patients undergoing pars plana vitrectomy for idiopathic macular holes of less than 1-year's duration.
  
  
  METHODS
  Pars plana core vitrectomy was performed on 107 eyes of 104 consecutive patients with acute idiopathic macular holes. One cohort had routine PTD. In the other cohort, no attempt was made to strip preretinal tissue. Follow-up was longer than 6 months (follow-up range, 6 to 36 months).
  
  
  RESULTS
  Overall, 95 (89%) of all macular holes were closed. Visual acuity improved 2 lines or more of the Snellen letter chart in 91 eyes (85%). A postoperative visual acuity of 20/50 or better was achieved in 79 eyes (74%). A transient increase in intraocular pressure (230 mm Hg) developed in 25 eyes (23.4%). In 6 eyes (5.6%) a retinal detachment developed. One eye had retinal pigment epithelial changes and 1 patient reported peripheral field loss. No statistically significant differences were noted between eyes having PTD and those without PTD for any outcome measure.
  
  
  CONCLUSIONS
  In this series, no beneficial or adverse effect could be demonstrated by performing PTD in eyes undergoing pars plana core vitrectomy for acute idiopathic macular holes.
authors.affiliation: Associated Retinal Consultants and William Beaumont Hospital, Royal Oak, Mich, USA. rmargherio@aol.com
authors.forename: R R
authors.initials: RR
authors.lastname: Margherio
authors.forename: A R
authors.initials: AR
authors.lastname: Margherio
authors.forename: G A
authors.initials: GA
authors.lastname: Williams
authors.forename: D R
authors.initials: DR
authors.lastname: Chow
authors.forename: M J
authors.initials: MJ
authors.lastname: Banach
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D004210:Dissection / Q000379:methods; D005260:Female; D005584:Fovea Centralis / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D012167:Retinal Perforations / Q000601:surgery*; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy