title: An evaluation of the management of epilepsy by primary health care nurses in Chitungwiza, Zimbabwe.
abstract: In order to design an effective training program for nurses on the management of epilepsy in Zimbabwe, the drug management of epilepsy by community health nurses without prior training in epilepsy management was evaluated. Epilepsy patients in Chitungwiza, a high-density suburb of Harare, were routinely managed at four health clinics run by nurses. The patients also attended a monthly epilepsy support group (ESG) program, which provided them with vocational and social rehabilitative support. Neurologists evaluated the drug therapy of all patients attending this support group program over a 2-year period. The specialist interventions required to drug therapy in patients with inadequate seizure control or drug side effects were noted. A total of 114 epilepsy patients (age range 8-56 years, M:F=1:1.2) were seen, of these 84.2% had generalized seizures, 40.3% of patients had been seizure-free for at least 6 months, 71.9% of patients were on phenobarbitone, while 59.6% were on monotherapy. No drug intervention was required to on-going drug therapy in 43% of patient consultations. The most important intervention in patients with inadequate seizure control was an increase in drug dose, required in 29% of consultations. Of serum drug level estimations in clinically indicated cases, 58% were below the therapeutic ranges. This tendency to sub-therapeutic dosing with AED amongst nurses implied that a written AED drug therapy protocol specifying optimal maintenance doses and dose increment schedules may be beneficial to the community-based nursing management of epilepsy.
authors.affiliation: Department of Medicine, University of Zimbabwe, Harare, Zimbabwe.
authors.forename: B
authors.initials: B
authors.lastname: Adamolekun
authors.forename: J
authors.initials: J
authors.lastname: Mielke
authors.forename: D
authors.initials: D
authors.lastname: Ball
authors.forename: T
authors.initials: T
authors.lastname: Mundanda
mesh_terms: D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000097:blood / Q000627:therapeutic use; D002648:Child; D003153:Community Health Services; D004827:Epilepsy / Q000188:drug therapy / Q000451:nursing* / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009726:Nurses; D012640:Seizures / Q000503:physiopathology / Q000628:therapy; D012657:Self-Help Groups; D015030:Zimbabwe
chemical_list: D000927:Anticonvulsants