title: [CD16+ CD56- indolent, NK cell-lineage granular lymphocyte proliferative disorder with autoimmune hemolytic anemia].
abstract: A 64-year-old man was given a diagnosis of CD16+ CD56- natural killer cell-lineage granular lymphocyte proliferative disorder (NK-GLPD) with Coombs-negative autoimmune hemolytic anemia (AIHA). Two courses of 1,000 mg intravenous methylprednisolone for 3 days were transiently effective for both AIHA and NK-GLPD. On the recurrence of AIHA, NK-GLPD also re-appeared. The same treatment was effective in controlling both diseases again. This was a rare case of NK-GLPD combined with autoimmune disease.
authors.affiliation: Department of Hematology, Yokohama City University Medical Center.
authors.forename: N
authors.initials: N
authors.lastname: Tomita
authors.forename: S
authors.initials: S
authors.lastname: Motomura
authors.forename: S
authors.initials: S
authors.lastname: Takemura
authors.forename: K
authors.initials: K
authors.lastname: Fujimaki
authors.forename: R
authors.initials: R
authors.lastname: Sakai
authors.forename: H
authors.initials: H
authors.lastname: Harano
authors.forename: Y
authors.initials: Y
authors.lastname: Ishigatsubo
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications*; D019002:CD56 Antigen / Q000032:analysis*; D006801:Humans; D007694:Killer Cells, Natural / Q000473:pathology*; D008232:Lymphoproliferative Disorders / Q000150:complications* / Q000276:immunology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D017452:Receptors, IgG / Q000032:analysis*
chemical_list: D019002:CD56 Antigen; D017452:Receptors, IgG