title: A study of the predisposition of Schistosomiasis mansoni to pyogenic liver abscess in experimentally infected mice.
abstract: In murine experimental model, the present work was carried out to study the possible predisposition of S. mansoni infection to pyogenic liver abscess, through a concurrent infection with Staphylococcus aureus. Pyogenic liver abscesses containing the bacterial organism were found in 85% of mice infected with concurrent early S. mansoni infection and S. aureus, in 35% of mice with late S. mansoni infection and the bacterial infection, and in 60% of mice with concurrent immunosuppressed late St. mansoni infection and staphylococcal infection. The early S. mansoni infection, immunosuppressed late schistosomiasis mansoni, and to a less extant late schistosomiasis mansoni, with concurrent bacterial infections can predispose to pyogenic liver abscess which has implicative effect on clinical cases.
authors.affiliation: Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
authors.forename: M S
authors.initials: MS
authors.lastname: Mahmoud
authors.forename: A A
authors.initials: AA
authors.lastname: Awad
mesh_terms: D000818:Animals; D005260:Female; D008100:Liver Abscess / Q000209:etiology*; D008297:Male; D051379:Mice; D012555:Schistosomiasis mansoni / Q000150:complications*; D013211:Staphylococcus aureus