Synthesis of diverse and complex molecules on the solid phase.
In this paper we summarize our efforts toward optimizing key reactions on the solid phase which tolerate a variety of functional groups. These groups were sequentially modified, allowing the production of novel and diverse compound libraries on the solid phase.
Wendeborn
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S
Novartis Crop Protection AG, Novartis Pharma AG, CH-4002 Basel, Switzerland. sebastian.wendeborn@cp.novartis.com
De Mesmaeker
A
A
Brill
W K
WK
Berteina
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S
D000818:Animals; D002625:Chemistry, Organic; D003500:Cyclization; D006801:Humans; D055601:Organic Chemistry Phenomena; D010165:Palladium
D010165:Palladium