Cardiac arrest and the role of thrombolytic agents.
Thrombolytic agents may have clinically significant beneficial effects in cardiac arrest. The application of thrombolytic drugs in the setting of current and antecedent cardiopulmonary resuscitation is well documented; however, it has not been systematically studied nor has it been widely considered. We provide a literature review of thrombolytic agents and cardiopulmonary resuscitation to discuss the need for randomized controlled trials and the possibility of benefits in acute resuscitation.
Newman
D H
DH
University of Pittsburgh Medical Center, Pittsburgh, PA, USA. Newman44@pol.net
Greenwald
I
I
Callaway
C W
CW
D016887:Cardiopulmonary Resuscitation; D003131:Combined Modality Therapy; D005343:Fibrinolytic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D006323:Heart Arrest / Q000188:drug therapy* / Q000401:mortality; D006801:Humans; D015996:Survival Rate; D015912:Thrombolytic Therapy; D016896:Treatment Outcome
D005343:Fibrinolytic Agents