title: Polipoza adenomatoasă familială--care operaţie? [Familial adenomatous polyposis--which operation?].
abstract: Familial adenomatous polyposis (FAP) syndromes are well recognized entities that benefit from surgical treatment which should not be delayed. Screening of first degree relatives is important. The aim of removing the colorectal mucosa with significant potential of malignant transformation can be achieved by means of three distinct procedures: panproctocolectomy and ileostomy, subtotal colectomy with ileorectal anastomosis, restorative proctocolectomy with ileoanal anastomosis. In a series of eight patients with FAP we performed mostly subtotal colectomy with ileorectal anastomosis. Of five patients who underwent a form of subtotal colonic resection, one was lost from follow up and two developed carcinoma in the remaining rectal mucosa, which necessitated completion of the resection with proctectomy and permanent ileostomy. Nevertheless, in the increasing number of patients amenable to regular outpatient supervision, there are strong points for recommending sphincter-saving operations.
authors.affiliation: Facultatea de Medicină, Universitatea de Medicina şi Farmacie Gr. T. Popa, Iaşi.
authors.forename: M
authors.initials: M
authors.lastname: Stoian
authors.forename: C
authors.initials: C
authors.lastname: Dolinescu
authors.forename: C
authors.initials: C
authors.lastname: Dăscălescu
authors.forename: S C
authors.initials: SC
authors.lastname: Stoica
authors.forename: S
authors.initials: S
authors.lastname: Pădureanu
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000175:diagnosis / Q000601:surgery*; D000328:Adult; D003082:Colectomy / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007081:Ileostomy / Q000379:methods; D008297:Male; D016737:Proctocolectomy, Restorative / Q000379:methods; D012007:Rectum / Q000601:surgery