[Dermatologic preparations with erythromycin--the correlation of the pharmaceutical form-therapeutic effect].
Erythromycin associated with progesterone and A vitamin has been included in three dermatological pharmaceutical forms: a lotion, a L/H emulsion and a L/H nonionogenic ointment. Aspect of these preparations has been noticed for a 90 days period. pH and electrical conductance were also determined during this interval. All the formulations mentioned above revealed insignificant variations of these parameters proving an appreciable physico-chemical stability. Clinical investigative studies in juvenile acne, showed efficiency, particularly for the emulsion form.
Cojocaru
I
I
Facultatea de Farmacie, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
Irimia
O
O
Constantin
T
T
D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000737:chemistry; D003879:Dermatologic Agents / Q000008:administration & dosage* / Q000737:chemistry; D004338:Drug Combinations; D004655:Emulsions; D004917:Erythromycin / Q000008:administration & dosage* / Q000737:chemistry; D006801:Humans; D006863:Hydrogen-Ion Concentration; D009824:Ointments; D010592:Pharmaceutic Aids / Q000737:chemistry; D012996:Solutions; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents; D004338:Drug Combinations; D004655:Emulsions; D009824:Ointments; D010592:Pharmaceutic Aids; D012996:Solutions; D004917:Erythromycin