title: Adrenal cortical carcinoma metastatic to the brain in a child.
abstract: A 9-year-old girl presented with profoundly decreased vision in both eyes and bilateral optic disc swelling. Magnetic resonance imaging showed a large intraventricular mass. Excisional biopsy diagnosed metastatic adrenal cortical carcinoma (ACC). This is, to the best of our knowledge, the first reported case of ACC metastatic to the brain in a child. It also illustrates the importance of differentiating optic neuritis from papilledema in children.
authors.affiliation: Bascom Palmer Eye Institute, University of Miami School of Medicine, Florida, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Piniella
authors.forename: R M
authors.initials: RM
authors.lastname: Siatkowski
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000473:pathology* / Q000601:surgery; D018268:Adrenocortical Carcinoma / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D001932:Brain Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D002552:Cerebral Ventricles / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009902:Optic Neuritis / Q000209:etiology; D010211:Papilledema / Q000209:etiology; D014786:Vision Disorders / Q000209:etiology