[State of the sympathoadrenal system and hemodynamics in children during congenital heart defect surgery with high thoracic epidural anesthesia using lidocaine-clofelin].
Effects of high thoracic epidural anesthesia (HTEA) on the hemodynamics and sympathoadrenal system were studied in patients during cardiopulmonary bypass surgery. In 55 patients aged 1-14 years, HTEA was used in combination with oxygen-air-halothane anesthesia. In one group lidocaine and fentanyl were used for HTEA and in another clonidine and lidocaine. In the control, standard intravenous fentanyl-diazepam anesthesia was combined with oxygen-air-halothane anesthesia. In the clonidine-lidocaine group the endocrine stress response was decreased in comparison with other groups even without narcotics; hemodynamics was stable even in patients with NYHA class III-IV.
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D000293:Adolescent; D000311:Adrenal Glands / Q000502:physiology*; D000367:Age Factors; D000700:Analgesics / Q000008:administration & dosage*; D000767:Anesthesia, Epidural / Q000379:methods*; D018685:Anesthetics, Inhalation / Q000008:administration & dosage; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D000779:Anesthetics, Local / Q000008:administration & dosage*; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage*; D002315:Cardiopulmonary Bypass; D002648:Child; D002675:Child, Preschool; D003000:Clonidine / Q000008:administration & dosage*; D005283:Fentanyl / Q000008:administration & dosage; D006221:Halothane / Q000008:administration & dosage; D006330:Heart Defects, Congenital / Q000601:surgery*; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D008012:Lidocaine / Q000008:administration & dosage*; D013564:Sympathetic Nervous System / Q000502:physiology*
D000700:Analgesics; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D000779:Anesthetics, Local; D000889:Anti-Arrhythmia Agents; D008012:Lidocaine; D003000:Clonidine; D005283:Fentanyl; D006221:Halothane