Metal-catalyzed acyl transfer reactions of enol esters: role of Y5(OiPr)13O and (thd)2Y(OiPr) as transesterification catalysts
Primary and secondary alcohols react with vinyl or isopropenyl acetate at room temperature in the presence of catalytic amounts (0.05-1 mol %) of Y5(OiPr)13O to give the corresponding esters. In selected cases, the yttrium catalyst promotes the selective O-acylation of amino alcohols without the formation of the amide. Enol esters also react with alpha-amino acid esters in the absence of a catalyst, at room temperature, to give the corresponding amides.
Lin
MH
Department of Chemistry, Ohio State University, Columbus 43210, USA.
RajanBabu
TV