title: Kyanomycin, a complex of unusual anthracycline-phospholipid hybrids from Nonomuria species.
abstract: A blue secondary metabolite complex, named kyanomycin (2), in addition to epsilon-rhodomycinone (1), was detected in the mycelium extract of Nonomuria sp. NN 22303 by HPLC-diode array and HPLC-electrospray mass spectrometry screening. The chemical structures of the novel compounds were determined to be unusual anthracycline-phosphatidylethanolamine hybrids by spectroscopic and chemical degradation experiments.
authors.affiliation: Mikrobiologisches Institut, Universität Tübingen, Auf der Morgenstelle 28, D-72076 Tübingen, Germany.
authors.forename: C M
authors.initials: CM
authors.lastname: Pfefferle
authors.forename: J
authors.initials: J
authors.lastname: Breinholt
authors.forename: C E
authors.initials: CE
authors.lastname: Olsen
authors.forename: R M
authors.initials: RM
authors.lastname: Kroppenstedt
authors.forename: E M
authors.initials: EM
authors.lastname: Wellington
authors.forename: H
authors.initials: H
authors.lastname: Gürtler
authors.forename: H P
authors.initials: HP
authors.lastname: Fiedler
mesh_terms: D000192:Actinomycetales / Q000737:chemistry*; D018943:Anthracyclines / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D008826:Microbial Sensitivity Tests; D010743:Phospholipids / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D018943:Anthracyclines; D000900:Anti-Bacterial Agents; D010743:Phospholipids; C408063:kyanomycin