[Venlafaxine withdrawal syndrome: report of six cases and review of the literature].
BACKGROUND
Venlafaxine is an antidepressant that selectively inhibits serotonin reuptake and is a norepinephrine inhibitor. Withdrawal syndromes can occur after abrupt drug discontinuation of long-term regimens.


METHODS
We report six cases of withdrawal symptoms after venlafaxine discontinuation.


CONCLUSIONS
Physicians must be aware of the frequency, rapidity and potent severity of these withdrawal syndromes.
Pinzani
V
V
Centre régional de pharmacovigilance, CHU de Montpellier, Montpellier, France.
Giniès
E
E
Robert
L
L
Peyrière
H
H
Abbar
M
M
Blayac
J P
JP
D000328:Adult; D017109:Akathisia, Drug-Induced / Q000209:etiology; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects*; D003511:Cyclohexanols / Q000009:adverse effects*; D003866:Depressive Disorder / Q000188:drug therapy; D005221:Fatigue / Q000139:chemically induced; D005260:Female; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006212:Hallucinations / Q000139:chemically induced; D006261:Headache / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged; D010292:Paresthesia / Q000139:chemically induced; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects*; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis / Q000209:etiology*; D013997:Time Factors; D000069470:Venlafaxine Hydrochloride
D018687:Antidepressive Agents, Second-Generation; D003511:Cyclohexanols; D017367:Selective Serotonin Reuptake Inhibitors; D000069470:Venlafaxine Hydrochloride