title: [Diabetes and urination disorders].
abstract: Diabetic neuropathy of can induce multi-organ dysfunction. The diabetes simultaneously has profound repercussions on gastrointestinal, sexual and erectile functions. One of the main sequelae of diabetic neuropathy is autonomic neuropathy affecting the vesicosphincteric control. The objective of this study was to review the epidemiological, clinical, laboratory and therapeutic data concerning voiding disorders observed in diabetes. Although the therapeutic management of an isolated voiding disorder in diabetics still remains symptomatic, it raises aetiological problems due to the comorbidity, particularly prostatic obstructive syndromes in men, pelvic dysfunction in women and ageing. Diabetic patients in renal failure also present specific vesicosphincteric disorders which are reviewed. Diabetic patients should be more systematically screened for the development of diabetic bladder disease, especially for associated factors which participate in its clinical expression. This implies extreme caution in the management of benign prostatic hyperplasia in the case of comorbidity, to avoid deteriorating a sometimes fragile detrusor-sphincter equilibrium. Diabetic detrusor hyperactivity must be better known in order to be more effectively detected. Pharmacological treatment of this condition raises problems related to detrusor hypocontractility also related to diabetic bladder disease. Clinical examination should be able to select those patients requiring further urodynamic studies in order to assess the individual detrusor-sphincter equilibrium. These investigations are required when surgical treatment of an associated urological or gynaecological disorder is considered.
authors.affiliation: Service d'Urologie, Hôpital de la Pitié-Salpétrière, Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Chartier-Kastler
authors.forename: M
authors.initials: M
authors.lastname: Averous
authors.forename: B
authors.initials: B
authors.lastname: Barrou
authors.forename: C
authors.initials: C
authors.lastname: Lopez
authors.forename: J
authors.initials: J
authors.lastname: Moscovici
authors.forename: F
authors.initials: F
authors.lastname: Roman
authors.forename: V
authors.initials: V
authors.lastname: Delmas
mesh_terms: D048909:Diabetes Complications; D003929:Diabetic Neuropathies / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D011470:Prostatic Hyperplasia / Q000150:complications; D001745:Urinary Bladder Diseases / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D014555:Urination Disorders / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D014563:Urodynamics