title: Instability of sleep patterns in children with attention-deficit/hyperactivity disorder.
abstract: OBJECTIVE
  To compare the stability of the sleep-wake system of children with attention-deficit/hyperactivity disorder (ADHD) and controls by objective and subjective measures.
  
  
  METHODS
  Thirty-eight school-age boys with diagnosed ADHD and 64 control school-age boys were examined using actigraphic monitoring and sleep diaries, over 5 consecutive nights.
  
  
  RESULTS
  Increased instability in sleep onset, sleep duration, and true sleep were found in the ADHD group compared with the control group. Discriminant analysis revealed that children's classification (ADHD versus control) could be significantly predicted on the basis of their sleep measures.
  
  
  CONCLUSIONS
  The findings support the hypothesis that instability of the sleep-wake system is a characteristic of children with ADHD. Given the potential negative effects of disturbed or unstable sleep on daytime functioning, it is recommended that a thorough sleep assessment be conducted when a sleep disturbance is suspected or when symptoms associated with daytime sleepiness or decreased arousal level are present.
authors.affiliation: Department of Psychology, Tel Aviv University, Israel. GruberR@intra.nimh.nih.gov
authors.forename: R
authors.initials: R
authors.lastname: Gruber
authors.forename: A
authors.initials: A
authors.lastname: Sadeh
authors.forename: A
authors.initials: A
authors.lastname: Raviv
mesh_terms: D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D015415:Biomarkers; D016022:Case-Control Studies; D002648:Child; D006801:Humans; D008297:Male; D017286:Polysomnography; D011569:Psychiatric Status Rating Scales; D020178:Sleep Disorders, Circadian Rhythm / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology
chemical_list: D015415:Biomarkers