Molecular epidemiological and phylogenetic associations of two novel putative virulence genes, iha and iroN(E. coli), among Escherichia coli isolates from patients with urosepsis.
Two novel putative Escherichia coli virulence genes, iha and iroN from E. coli (iroN(E. coli)), were detected in 55 and 39%, respectively, of 67 E. coli isolates from patients with urosepsis. iha and iroN(E. coli) exhibited divergent associations with other putative virulence genes, phylogenetic markers, host characteristics, and antimicrobial resistance.
Johnson
J R
JR
Medical Service, VA Medical Center, and Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55417, USA. johns007@tc.umn.edu
Russo
T A
TA
Tarr
P I
PI
Carlino
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U
Bilge
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Vary
J C
JC
Stell
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D000328:Adult; D000483:Alleles; D001426:Bacterial Proteins / Q000145:classification / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics*; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000276:immunology; D029968:Escherichia coli Proteins; D036781:Fimbriae Proteins; D005798:Genes, Bacterial; D006801:Humans; D010802:Phylogeny; D018805:Sepsis / Q000382:microbiology*; D014774:Virulence
C078802:AtpA protein, E coli; D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D036781:Fimbriae Proteins