[Treatment by corticosteroid and plasma exchange in 5 cases of renal cholesterol embolic disease].
Cholesterol arterial embolization is a systemic disease resulting from cholesterol crystal embolization to multiple organs, including the kidney, skin, brain, eye, gastrointestinal tract and extremities. In general, it is associated with high morbidity and mortality, but no optimal treatment has yet been developed. In this paper, we report five patients with cholesterol atheroembolic renal failure. In three of the five patients, combined therapy with corticosteroids and plasma exchange was performed. The three patients survived. On the other hand, the two remaining patients died of multifactorial causes. In this report, the literature on steroid therapy for cholesterol atheroembolic renal disease is reviewed and the efficacy of combined therapy by use of corticosteroids and plasma exchange is evaluated.
Hasegawa
M
M
Department of Nephrology, Fujita Health University School of Medicine, Aichi, Japan.
Kawashima
S
S
Shikano
M
M
Hasegawa
H
H
Tomita
M
M
Murakami
K
K
Kushimoto
H
H
Katsumata
H
H
Toba
T
T
Yoshikawa
H
H
Yoshimura
E
E
Koide
S
S
Murase
M
M
Fujii
M
M
D058186:Acute Kidney Injury / Q000628:therapy*; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D017700:Embolism, Cholesterol / Q000628:therapy*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D008875:Middle Aged; D010951:Plasma Exchange; D011239:Prednisolone / Q000627:therapeutic use*; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D011239:Prednisolone; D008775:Methylprednisolone