title: Amniocentesis for selection before rescue cerclage.
abstract: OBJECTIVE
  To determine whether diagnostic amniocentesis should be part of evaluations of women under consideration for rescue cerclage.
  
  
  METHODS
  We reviewed the obstetric records of 25 candidates for rescue cerclage seen between June 30, 1995, and July 1, 1997. Rescue cerclage was defined as a procedure on a cervix with an internal os dilated at least 2 cm and 50% effaced, with membranes visible at the external os. Transabdominal amniocentesis was offered as part of the preoperative evaluation, and amniotic fluid (AF) was sent for glucose and lactate dehydrogenase level determinations, Gram staining, and culture for aerobic and anaerobic bacteria. Placentas were examined for histopathologic evidence of inflammation. The women were divided into three groups. Eleven women had rescue cerclage after amniocentesis, seven had rescue cerclage after declining amniocentesis, and seven had amniocentesis but were treated conservatively because of AF markers of infection. Analysis of variance and chi(2) statistics were used.
  
  
  RESULTS
  The group that had rescue cerclage after amniocentesis had a significantly longer mean admission-to-delivery interval, higher mean gestational age at delivery, higher mean birth weight, and higher neonatal survival rate than did the group that had rescue cerclage without amniocentesis and the group that had no cerclage after amniocentesis (P <.001).
  
  
  CONCLUSIONS
  Amniocentesis before rescue cerclage placement identified women with subclinical chorioamnionitis who would not benefit from cerclage.
authors.affiliation: Maternal-Fetal-Medicine Division, Department of Obstetrics and Gynecology, Metropolitan Hospital Center, New York, New York, USA.
authors.forename: J K
authors.initials: JK
authors.lastname: Mays
authors.forename: R
authors.initials: R
authors.lastname: Figueroa
authors.forename: J
authors.initials: J
authors.lastname: Shah
authors.forename: H
authors.initials: H
authors.lastname: Khakoo
authors.forename: S
authors.initials: S
authors.lastname: Kaminsky
authors.forename: N
authors.initials: N
authors.lastname: Tejani
mesh_terms: D000022:Abortion, Spontaneous / Q000517:prevention & control*; D000328:Adult; D000649:Amniocentesis; D000653:Amniotic Fluid / Q000382:microbiology; D002584:Cervix Uteri / Q000601:surgery*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D011256:Pregnancy Outcome; D002581:Uterine Cervical Incompetence / Q000175:diagnosis* / Q000601:surgery*