title: Remote effects of acute ischemic stroke: A xenon CT cerebral blood flow study.
abstract: OBJECTIVE
  The purpose of this study was to verify transhemispheric diaschisis in the early hours after an ischemic event.
  
  
  METHODS
  XeCT cerebral blood flow (CBF) studies within 8 h of stroke were studied in 23 patients. Mean CBF was evaluated in the ischemic area, contralateral hemisphere and ipsilateral cerebellum.
  
  
  RESULTS
  A severe CBF reduction was found in the ischemic area (mean 9 +/- 3 ml/100 g/min). The mean CBF in the unaffected hemisphere (33 +/- 10 ml/100 g/min) was 35% less compared to the normal mean value. CBF was decreased in the cerebellum ipsilateral to the stroke (mean 31 +/- 12 ml/100 g/min) suggesting a blood flow depression of the whole brain.
  
  
  CONCLUSIONS
  During the initial hours of cerebral ischemia, the asymptomatic hemisphere demonstrated CBF depression that was part of the global flow reduction.
authors.affiliation: Department of Neurosurgery, University of Pittsburgh, Pittsburgh, PA, USA.
authors.forename: G
authors.initials: G
authors.lastname: Rubin
authors.forename: E I
authors.initials: EI
authors.lastname: Levy
authors.forename: A M
authors.initials: AM
authors.lastname: Scarrow
authors.forename: A D
authors.initials: AD
authors.lastname: Firlik
authors.forename: A
authors.initials: A
authors.lastname: Karakus
authors.forename: L
authors.initials: L
authors.lastname: Wechsler
authors.forename: C A
authors.initials: CA
authors.lastname: Jungreis
authors.forename: H
authors.initials: H
authors.lastname: Yonas
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020771:Anterior Cerebral Artery / Q000000981:diagnostic imaging; D001921:Brain / Q000098:blood supply*; D002545:Brain Ischemia / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D007839:Functional Laterality; D006801:Humans; D008875:Middle Aged; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging; D012039:Regional Blood Flow; D020521:Stroke / Q000000981:diagnostic imaging / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed; D014978:Xenon
chemical_list: D014978:Xenon