The complete nucleotide sequence of segment L2 of Ibaraki virus encoding for the antigen recognized by neutralizing antibodies.
The complete nucleotide sequence of cDNA clones representing the L2 dsRNA from Japan isolate of epizootic hemorrhagic disease serotype 2 (EHDV-2JPN) was determined. The EHDV-2JPN L2 gene is 3002 base pairs long with a single open reading frame of 2949 bp which predicts a polypeptide of 982 amino acid residues. Comparison of VP2 sequence between Japan and North American Isolates of EHDV-2 showed a 72% homology in spite of the same serotype, although those among the North American isolates showed a high genetic identity (>97%).
Nara Pereira
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EM
Department of Veterinary Hygiene, Faculty of Agriculture, Yamaguchi University, Japan.
Iwata
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Inoue
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D000818:Animals; D000956:Antigens, Viral / Q000737:chemistry / Q000235:genetics*; D001483:Base Sequence; D002478:Cells, Cultured; D003001:Cloning, Molecular; D006031:Glycosylation; D018164:Hemorrhagic Disease Virus, Epizootic / Q000235:genetics*; D008969:Molecular Sequence Data; D009500:Neutralization Tests / Q000662:veterinary; D017386:Sequence Homology, Amino Acid; D014764:Viral Proteins
D000956:Antigens, Viral; C411967:L2 protein, Ibaraki virus; D014764:Viral Proteins