Exercise induced bronchospasm in asthmatic and non-asthmatic obese children.
OBJECTIVE
to investigate the spirometric response to the exercise challenge in asthmatic and non-asthmatic obese children.


METHODS
it was a prospective, longitudinal, open label clinical trial with four groups of children from 8 to 16 years. The group 1 had 15 asthmatic non-obese children. The group 2 had 15 asthmatic obese children. The group 3 had 15 non-asthmatic obese children. The group 4 had 13 control healthy children. Spirometry measures were realized at baseline, and after exercise at 2, 5, 10, 15, 20, 25, 30 and 60 minutes. Exercise challenge was performed on a walking band at 6 km/h speed and a slope of 10 degrees with a duration of 6 to 8 minutes. Data were are analyzed by repeated measures ANOVA.


RESULTS
the mean age was 11.8 +/- 2.1, and the mean height was 150.2 +/- 11.3 cm, the mean weight was 46.3 +/- 17.15 in the group 1, 59.4 +/- 11.9 in the group 2, 67.8 +/- 20.6 in the group 3, and 44.2 +/- 9.7 in the group 4. The mean values of forced expiratory volume in one second (FEV1) for each group are shown on table II.


CONCLUSIONS
the non-asthmatic obese children had a significant decrease in FEV1, meanwhile the asthmatic obese children had a deeper decrease in FEV1 than the asthmatic non-obese children. Obesity ay be a conditioning factor for bronchial hyperreactivity to the exercise.
del Río-Navarro
B
B
Hospital Infantil de México "Federico Gómez", Ciudad de México D. F., 06720, México.
Cisneros-Rivero
M
M
Berber-Eslava
A
A
Espínola-Reyna
G
G
Sienra-Monge
J
J
D000273:Adipose Tissue / Q000473:pathology; D000293:Adolescent; D001249:Asthma / Q000150:complications* / Q000453:epidemiology; D015992:Body Mass Index; D016535:Bronchial Hyperreactivity / Q000209:etiology* / Q000503:physiopathology; D001986:Bronchial Spasm / Q000209:etiology* / Q000503:physiopathology; D002648:Child; D015897:Comorbidity / Q000639:trends; D005080:Exercise Test; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D009765:Obesity / Q000150:complications* / Q000453:epidemiology; D005082:Physical Exertion; D011446:Prospective Studies; D015656:Respiratory Mechanics; D012307:Risk Factors; D013147:Spirometry