title: Coma from fat embolism syndrome after hemiarthroplasty of the hip for metastatic breast cancer to the proximal femur: a case report.
abstract: We present a case report of fat embolism syndrome (FES) that resulted in prolonged coma after cemented hemiarthroplasty in a patient with metastatic breast cancer. After the cemented hip prosthesis was placed, the patient developed decreased sensorium that progressed to coma in association with hypoxemia and tachypnea. Pulmonary compromise was mild, and the patient required only supplemental oxygen for support. The patient demonstrated no petechiae. Magnetic imaging results were consistent with FES. While the pulmonary symptoms resolved quickly, the patient remained unresponsive for 11 days without purposeful motor function. After waking she recovered rapidly, and at her 2-month follow-up appointment, demonstrated no adverse orthopedic, pulmonary, or neurologic sequelae.
authors.affiliation: Department of Surgery, University of Wisconsin, Madison, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Lairmore
authors.forename: J
authors.initials: J
authors.lastname: Heiner
authors.forename: K
authors.initials: K
authors.lastname: Wood
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D001943:Breast Neoplasms / Q000473:pathology; D003128:Coma / Q000209:etiology*; D004620:Embolism, Fat / Q000150:complications*; D005260:Female; D005266:Femoral Neoplasms / Q000150:complications / Q000556:secondary / Q000601:surgery*; D006620:Hip Fractures / Q000209:etiology; D006801:Humans; D011183:Postoperative Complications