title: Lymphohistiocytic anaplastic large cell lymphoma stage I: long-term survival after resection alone.
abstract: A 17-year-old female presented with axillary lymphoadenopathy, which, on biopsy, demonstrated an anaplastic large cell lymphoma of the lymphohistiocytic type (ALCL-LH). The tumor cells expressed the CD30 antigen and reacted with the ALK1 antibody, suggesting the presence of the nucleophosmin-anaplastic large cell lymphoma kinase (NPM/ALK) fusion protein. No other adenopathy was found. Following a wide excision of the lymph node and without postoperative treatment, the patient remains free of disease 5 years later. This case demonstrates the potential curability of patients with early stages of ALCL by local treatment.
authors.affiliation: University of Florida College of Medicine, Gainesville 32610-0296, USA. Kedara@peds.ufl.edu
authors.forename: A
authors.initials: A
authors.lastname: Kedar
authors.forename: R C
authors.initials: RC
authors.lastname: Braylan
mesh_terms: D000293:Adolescent; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D017728:Lymphoma, Large-Cell, Anaplastic / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D013997:Time Factors