title: Laryngeal pathology detection by means of class-specific neural maps.
abstract: Most of the existing systems and methods for laryngeal pathology detection are characterized by a classification error. One of the basic problems is the approximation and estimation of the probability density functions of the given classes. In order to increase the accuracy of laryngeal pathology detection and to eliminate the most dangerous error--classification of a patient with laryngeal disease as a normal speaker--here an approach based on modeling of the probability density functions (pdf's) of the input vectors of the normal and pathological speakers by means of two prototype distribution maps (PDM), respectively, is proposed. The pdf of the input vectors of an unknown normal or pathological speaker is also modeled by such a prototype distribution neural map--PDM(X)--and the pathology detection is done by means of a ratio of specific similarities rather than by a direct comparison of some type of distance/similarity with a threshold. The experiments show an increased classification accuracy and that the proposed method can be used for screening the laryngeal diseases. The method is applied in a consulting system for clinical practice.
authors.affiliation: Central Laboratory of Biomedical Engineering, Bulgarian Academy of Sciences, Sofia.
authors.forename: S
authors.initials: S
authors.lastname: Hadjitodorov
authors.forename: B
authors.initials: B
authors.lastname: Boyanov
authors.forename: B
authors.initials: B
authors.lastname: Teston
mesh_terms: D000465:Algorithms; D003661:Decision Support Techniques; D003936:Diagnosis, Computer-Assisted; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007818:Laryngeal Diseases / Q000145:classification / Q000175:diagnosis*; D016571:Neural Networks, Computer; D010699:Phonation / Q000502:physiology; D011336:Probability; D012680:Sensitivity and Specificity; D013060:Speech / Q000502:physiology; D014831:Voice / Q000502:physiology; D014832:Voice Disorders / Q000145:classification