title: [Proctocolectomy with an ileal pouch-anal anastomosis; results from 100 consecutive patients in the Academic Medical Center at Amsterdam, 1994-1999].
abstract: OBJECTIVE
  To evaluate the results of proctocolectomy with creation of an ileac pouch anal anastomosis (IPAA).
  
  
  METHODS
  Retrospective.
  
  
  METHODS
  Of the 100 patients in whom an IPAA procedure was performed in the period 1994/'99 in the Department of Surgery of the Academic Medical Centre, Amsterdam, the Netherlands, data were collected on the complications: in the patients with a follow-up of over 12 months the functional results were studied.
  
  
  RESULTS
  The group comprised 48 males and 52 females with a mean age of 36.3 years (range: 15-62). Preoperative diagnoses were ulcerative colitis (n = 84), familial polyposis coli (12), slow transit obstipation (2), Hirschsprung's disease (1) and Muir-Torre syndrome (1). Median operating time was 2.3 h, peroperative blood and fluid loss 500 ml and median hospital stay 15 days. There was no mortality. Ten patients had a loop ileostomy formation, in 6 because of postoperative complications. A total of 30 patients developed postoperative complications, peroperatively or during follow-up 10 of those patients needed a relaparotomy. After 12 months 1 pouch had to be excised and 2 patients still had a loop ileostomy due to postoperative complications. In 56 patients with at least 12 months follow-up, median 24-hour stool frequency was 6. Eighty-nine per cent of these patients were satisfied or highly satisfied with the overall outcome.
  
  
  CONCLUSIONS
  A proctocolectomy with IPAA formation is a safe procedure with good functional results.
authors.affiliation: Academish Medisch Centrum, afd. Heelkunde, Amsterdam. p.vanduijvendijk@amc.uva.nl
authors.forename: P
authors.initials: P
authors.lastname: van Duijvendijk
authors.forename: J F
authors.initials: JF
authors.lastname: Slors
authors.forename: C W
authors.initials: CW
authors.lastname: Taat
authors.forename: W A
authors.initials: WA
authors.lastname: Bemelman
authors.forename: L T
authors.initials: LT
authors.lastname: van Lochem
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery; D011125:Adenomatous Polyposis Coli / Q000601:surgery; D000293:Adolescent; D000328:Adult; D003093:Colitis, Ulcerative / Q000601:surgery; D003108:Colonic Diseases / Q000601:surgery*; D003110:Colonic Neoplasms / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006627:Hirschsprung Disease / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D016737:Proctocolectomy, Restorative / Q000009:adverse effects / Q000379:methods; D012086:Reoperation; D012189:Retrospective Studies; D012494:Sampling Studies; D016896:Treatment Outcome