title: Spectinomycin resistance in Neisseria spp. due to mutations in 16S rRNA.
abstract: Spectinomycin resistance in clinical isolates of Neisseria meningitidis and Neisseria gonorrhoeae was found to be due to mutations G1064C and C1192U (Escherichia coli numbering) in 16S rRNA genes, respectively.
authors.affiliation: Unité des Agents Antibactériens, Institut Pasteur, 75724 Paris Cedex 15, France. galimand@pasteur.fr
authors.forename: M
authors.initials: M
authors.lastname: Galimand
authors.forename: G
authors.initials: G
authors.lastname: Gerbaud
authors.forename: P
authors.initials: P
authors.lastname: Courvalin
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics; D006801:Humans; D009344:Neisseria gonorrhoeae / Q000187:drug effects / Q000235:genetics*; D009345:Neisseria meningitidis / Q000187:drug effects / Q000235:genetics*; D017354:Point Mutation; D012329:RNA, Bacterial / Q000235:genetics; D012336:RNA, Ribosomal, 16S / Q000235:genetics*; D000198:Spectinomycin / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D012329:RNA, Bacterial; D012336:RNA, Ribosomal, 16S; D000198:Spectinomycin