[The action of a new taurine derivative in different variants of hypoxic states].
A new N-phenylalkyl derivative of taurin was tested. The results show that this compound exhibits a pronounced general antihypoxant activity and is capable of increasing the stability of heart with respect to hypoxia and anoxia, protecting heart against the ischemic damage, and facilitating the adaptation capacity of myocardium.
Torkunov
P A
PA
Department of Neuropharmacology, Russian Academy of Medical Sciences, St. Petersburg, Russia.
Sapronov
N S
NS
D000222:Adaptation, Physiological / Q000187:drug effects; D000818:Animals; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D006321:Heart / Q000187:drug effects / Q000503:physiopathology; D000860:Hypoxia / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D051379:Mice; D017202:Myocardial Ischemia / Q000188:drug therapy / Q000503:physiopathology; D013654:Taurine / Q000031:analogs & derivatives* / Q000627:therapeutic use*
D013654:Taurine