title: Intra-arterial thrombolysis for the treatment of perioperative childhood cardioembolic stroke.
abstract: Local intra-arterial lysis using recombinant tissue plasminogen activator (rTPA) was performed in a 6 and 2/3-year-old patient with major cardioembolic ischemic stroke 48 hours after intracardiac surgery. Selective application of 2.5 mg rTPA (0.11 mg/kg body weight) resulted in recanalization of the occluded cerebral vasculature with good neurologic recovery.
authors.affiliation: Departments of Neurosurgery, University of Vienna Medical School, Austria.
authors.forename: A
authors.initials: A
authors.lastname: Gruber
authors.forename: C
authors.initials: C
authors.lastname: Nasel
authors.forename: W
authors.initials: W
authors.lastname: Lang
authors.forename: E
authors.initials: E
authors.lastname: Kitzmüller
authors.forename: G
authors.initials: G
authors.lastname: Bavinzski
authors.forename: T
authors.initials: T
authors.lastname: Czech
mesh_terms: D006348:Cardiac Surgical Procedures / Q000009:adverse effects; D002533:Cerebral Angiography; D002648:Child; D005260:Female; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D015552:Injections, Intralesional; D008279:Magnetic Resonance Imaging; D011183:Postoperative Complications / Q000209:etiology / Q000628:therapy; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D010959:Tissue Plasminogen Activator