A case report of frosted branch angiitis and its visual electrophysiology.
We reported a 5-years old boy with frosted branch angiitis in both eyes. The visual acuities of the two eyes were suddenly lost to 5/50. The fluorescein angiography, electroretinograms (ERGs) and pattern evoked potentials (PVEPs) had been tested at the acute and the recovery stage of the disease. At the onset of the disease, fluorescein angiography showed obvious dye leakage from dilated retinal veins. The PVEPs and whole field ERGs including rod, maximum, OPs and cone responses were seriously decreased and prolonged, indicating that the visual pathway's and retinal functions were greatly damaged. The patient had an excellent response to systemic prednisone. One month after the treatment, the visual acuities recovered to 60/50 in both eyes. The fluorescein angiography showed that leakage from blood vessels was diminished, but the lesions at macula and optic disc were persisted a longer time even to the end of treatment. Through 6 months medication, nearly all of the electrophysiological abnormalities had been resolved.
Luo
G
G
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, China. guangweiluo@163.net
Yang
P
P
Huang
S
S
Jiang
F
F
Wen
F
F
D000284:Administration, Oral; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D012164:Retinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D012171:Retinal Vessels / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology*; D014657:Vasculitis / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D014792:Visual Acuity
D005938:Glucocorticoids; D011241:Prednisone