Anti-schistosome antibody responses in children coinfected with malaria.
People residing in schistosome endemic areas are often infected with other parasites. The interaction of the parasites in the host has important implications in the development of acquired immunity to schistosomiasis, and schistosome immuno-epidemiology. An analysis of specific anti-schistosome egg responses in children coinfected with schistosomiasis and malaria shows that malaria positive children produce significantly more anti-schistosome IgE and IgG3 than schistosome infected children who are negative for malaria.
Mutapi
F
F
Wellcome Trust Centre for the Epidemiology of Infectious Diseases, Department of Zoology, South Parks Road, University of Oxford, Oxford OX1 3PS, UK.
Ndhlovu
P D
PD
Hagan
P
P
Woolhouse
M E
ME
D000293:Adolescent; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D002648:Child; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D008288:Malaria / Q000150:complications* / Q000276:immunology*; D008297:Male; D012548:Schistosoma haematobium / Q000276:immunology*; D012553:Schistosomiasis haematobia / Q000150:complications* / Q000276:immunology*; D015030:Zimbabwe
D000909:Antibodies, Helminth; D007074:Immunoglobulin G; D007073:Immunoglobulin E