title: Antifungal and larvicidal compounds from the root bark of Cordia alliodora.
abstract: Two new natural products, a phenylpropanoid derivative characterized as 1-(3'-methoxypropanoyl)-2,4,5-trimethoxybenzene (1) and a prenylated hydroquinone, 2-(2Z)-(3-hydroxy-3,7-dimethylocta-2, 6-dienyl)-1,4-benzenediol (2), have been isolated from the root bark of Cordia alliodora. Both compounds exhibited antifungal properties against the phytopathogenic mold Cladosporium cucumerinum. The phenylpropanoid derivative (1), whose structure is closely related to beta-asarone, also demonstrated a marked activity against larvae of the yellow-fever-transmitting mosquito Aedes aegypti.
authors.affiliation: Institut de Pharmacognosie et Phytochimie, Université de Lausanne, BEP, CH-1015 Lausanne, Switzerland.
authors.forename: J R
authors.initials: JR
authors.lastname: Ioset
authors.forename: A
authors.initials: A
authors.lastname: Marston
authors.forename: M P
authors.initials: MP
authors.lastname: Gupta
authors.forename: K
authors.initials: K
authors.lastname: Hostettmann
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006873:Hydroquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007814:Larva / Q000187:drug effects*; D015394:Molecular Structure; D009795:Octanes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010666:Phenylpropionates / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: C408010:1-(3'-methoxypropanoy)-2,4,5-trimethoxy benzene; C408011:2-(2Z)-(3-hydroxy-3,7-dimethylocta-2,6-dienyl)-1,4-benzenediol; D000935:Antifungal Agents; D006873:Hydroquinones; D009795:Octanes; D010666:Phenylpropionates