title: [Molecular mechanism of alpha-herpesvirus proliferation].
abstract: Among members of the subfamily alpha herpesviruses, herpes simplex virus (HSV) is one of the most well-studied and the most important human pathogen. HSV is reported to possess the large, double-stranded DNA genome which contains at least 80 genes. Recent studies have revealed the functions and roles of many gene products in HSV-infected cells. This article briefly reviews the results of these studies relating to HSV replication mechanism in cells and latent infection in central nerve system (CNS).
authors.affiliation: Laboratory of Virology, Nagoya University School of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Murata
authors.forename: Y
authors.initials: Y
authors.lastname: Nishiyama
mesh_terms: D006561:Herpes Simplex; D006801:Humans; D018139:Simplexvirus / Q000235:genetics / Q000254:growth & development*