title: Role of radionuclide perfusion study in cold solitary thyroid nodule for diagnosis of malignancy: a complimentary diagnostic modality to fine needle aspiration cytology.
abstract: One hundred and forty eight subjects with euthyroid solitary thyroid nodules (STN) were taken up for radionuclide perfusion study. They were found to have a cold STN on 99mTc thyroid static scan. All had fine needle aspiration cytology (FNAC), and except for subjects with chronic lymphocytic thyroiditis, were subjected to surgery for tissue diagnosis by histopathology. The diagnostic findings in these patients of solitary thyroid nodules were correlated with the histopathology. Radionuclide perfusion study is considered useful to differentiate benign from malignant cold thyroid solitary nodules with high degree of sensitivity (95%) and specificity (87.9%).
authors.affiliation: Dept. of Nuclear Medicine, Institute of Nuclear Medicine and Allied Sciences (INMAS), Delhi.
authors.forename: R
authors.initials: R
authors.lastname: Sharma
authors.forename: A
authors.initials: A
authors.lastname: Mondal
authors.forename: M
authors.initials: M
authors.lastname: Sahoo
authors.forename: A
authors.initials: A
authors.lastname: Kakar
authors.forename: L R
authors.initials: LR
authors.lastname: Shankar
authors.forename: C M
authors.initials: CM
authors.lastname: Khanna
authors.forename: M K
authors.initials: MK
authors.lastname: Chopra
authors.forename: N L
authors.initials: NL
authors.lastname: Soni
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D016606:Thyroid Nodule / Q000000981:diagnostic imaging* / Q000473:pathology*