[Morphological data correlated with the mechanism of striated muscle contraction].
The classical theory of muscle contraction (Huxley, 1957) could not entirely explain a series of theoretical and experimental data. This theory sustains a longitudinal sliding of thin filaments on thick ones, by the tilting of myosin cross-bridges. Under different stimuli inducing contractions, the stereospecific conformations of cross-bridges appear to be different as it is shown using electron microscopy, fluorescence polarization, electron paramagnetic resonance (EPR) spectroscopy and equatorial X-ray diffraction. Our optic microscopy data also suggest the existence of such conformations, induced by different contractile stimuli.
Vasile
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DM
Disciplina de Fiziopatologie, Facultatea de Stomatologie, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
Niţă
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M
Costuleanu
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D000818:Animals; D001707:Biopsy, Needle; D006652:Histological Techniques; D006801:Humans; D007366:Intercostal Muscles / Q000033:anatomy & histology* / Q000502:physiology; D009119:Muscle Contraction; D018482:Muscle, Skeletal / Q000033:anatomy & histology* / Q000502:physiology; D051381:Rats; D013848:Thigh