title: Relationships between femoral fracture loads for two load configurations.
abstract: Studies of proximal femoral strength usually involve one of two types of loading conditions, loading similar to joint loading during single-limb stance or loading simulating impact from a fall. When interpreting the results of studies involving only one of these load configurations, the question arises as to their applicability to the other configuration. In addition, it is desirable to know whether, for an individual bone, fracture load for one load configuration is indicative of fracture load for the other configuration. In this study, the relationship between proximal femoral fracture loads for single-limb stance loading and loading simulating impact from a type of fall was determined from mechanical testing of 17 matched pairs of human proximal femora. Fracture loads for these two configurations were found to be linearly related (r = 0.901, p < 0.001). However, the correlation between fracture loads is not notably stronger than correlations currently available between fracture load and measures of bone density and geometry. In addition, the regression results indicate that 81% of the variance in fracture load for one loading condition is accounted for by fracture load for the other loading condition. Thus, 19% of the variance remains unexplained, indicating that the results of studies involving only one load configuration are not necessarily indicative of those that would be found for another configuration.
authors.affiliation: Department of Orthopaedic Surgery, University of California Irvine Medical Center, Orange 92868-5382, USA. jhkeyak@uci.edu
authors.forename: J H
authors.initials: JH
authors.lastname: Keyak
mesh_terms: D000058:Accidental Falls; D001696:Biomechanical Phenomena; D005264:Femoral Fractures / Q000503:physiopathology*; D006801:Humans; D011187:Posture / Q000502:physiology; D016474:Weight-Bearing