Vitamin E serum levels and gastric cancer: results from a cohort of patients in Tuscany, Italy.
Alpha-tocopherol has been reported to play an important role against oxidative damage and in the inhibition of cell transforming and mutagenesis. We analysed vitamin E serum levels in 51 cases of patients affected by gastric cancer at different stages of the disease, and in 49 age-matched controls. All patients had normal values of alpha-tocopherol. However, when patients have been grouped according to histotype of gastric lesions, a significant vitamin E increase has been found in diffuse gastric cancer histotype compared to the intestinal histotype. Our results suggest that a correlation between vitamin E serum levels and gastric cancer histotype should be considered.
Battisti
C
C
OU of Neurometabolic Disease, Institute of Neurological Sciences, University of Siena, Italy.
Formichi
P
P
Tripodi
S A
SA
Vindigni
C
C
Roviello
F
F
Federico
A
A
D000368:Aged; D002784:Cholesterol / Q000097:blood; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000097:blood* / Q000145:classification / Q000453:epidemiology / Q000473:pathology; D014421:Turkey / Q000453:epidemiology; D014810:Vitamin E / Q000097:blood*
D014810:Vitamin E; D002784:Cholesterol