Excoecarins D, E, and K, from excoecaria agallocha.
Three novel diterpenoids, excoecarins D, E, and K (1-3), were isolated from Excoecaria agallocha. The structures of 1-3 were established as 3alpha,18-dihydroxy-3beta,20-epoxybeyer-15-ene, (15R, 16S)-ent-15,16-epoxybeyeran-3-one, and ent-3beta-hydroxykaur-16-en-2-one, respectively, on the basis of extensive NMR experiments and, in the case of 1, by X-ray analysis.
Konishi
T
T
Kyoto Pharmaceutical University, 5 Nakauchi-cho, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan. konishi@mb.kyoto-phu.ac.jp
Konoshima
T
T
Fujiwara
Y
Y
Kiyosawa
S
S
D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D019665:Euphorbiaceae / Q000737:chemistry*; D015394:Molecular Structure; D013057:Spectrum Analysis
D004224:Diterpenes