Disseminated histoplasmosis and AIDS: clinical aspects and diagnostic methods for early detection.
Disseminated histoplasmosis in AIDS patients is the focus of this paper. Cutaneous lesions are reported as a frequent clinical sign. Bone marrow aspiration and biopsy, blood cultures (lysis-centrifugation technique), bronchoalveolar lavage, and skin lesion scrapings are the most effective diagnostic methods. The identification of a specific antigen in blood and urine may be a rapid means of evaluation and follow-up of patients with this disease.
Corti
M E
ME
Unit 10 and Micology Center, F.J. Muñiz Infectious Diseases Hospital, Buenos Aires, Argentina. marcelocorti@cuidad.com.ar
Cendoya
C A
CA
Soto
I
I
Esquivel
P
P
Trione
N
N
Villafañe
M F
MF
Corbera
K M
KM
Helou
S
S
Negroni
R
R
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D000935:Antifungal Agents / Q000008:administration & dosage; D001118:Argentina / Q000453:epidemiology; D005260:Female; D016469:Fungemia / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D006660:Histoplasmosis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D011379:Prognosis; D012307:Risk Factors
D000935:Antifungal Agents