The spectrum of human herpesvirus 6 infection: from roseola infantum to adult disease.
Human herpesvirus 6 is the causative agent of roseola infantum, a generally benign rash illness of infants. Most persons acquire HHV-6 infection by age 2 years, and HHV-6 infection is a common cause of fever and febrile seizures in infants. In adults, primary infection with HHV-6 can produce a mononucleosis-like illness and, more rarely, severe disease, including encephalitis. In addition to primary infections, HHV-6 can cause clinical illness during reactivation, particularly in immunocompromised persons.
Stoeckle
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Weil Medical College of Cornell University, New York, New York 10021, USA. mystoeckle@bigfoot.com
D000328:Adult; D002648:Child; D005077:Exanthema Subitum / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology*; D006566:Herpesviridae Infections / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology*; D015654:Herpesvirus 6, Human; D006801:Humans