[Inflammation mediated osteopenia (IMO): therapeutic effect of D-hormone and the role of cytokines].
Inflammation-mediated osteopenia is an animal model for bone mass reduction following chronic inflammation. We found a reduction of calcitriol serum concentrations during the inflammatory process, in addition cytokines are increased. Treatment of the animals with calcitriol is able to prevent bone mass reduction and to preserve bone formation.
Scharla
S H
SH
Abteilung Innere Medizin, Klinikum Berchtesgadener Land, Schönau am Königssee.
Lempert
U G
UG
Kamilli
I
I
D000818:Animals; D015519:Bone Density / Q000187:drug effects / Q000276:immunology; D001851:Bone Diseases, Metabolic / Q000188:drug therapy / Q000276:immunology*; D002117:Calcitriol / Q000627:therapeutic use; D016207:Cytokines / Q000502:physiology*; D004195:Disease Models, Animal; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000276:immunology*; D051381:Rats; D016896:Treatment Outcome; D014807:Vitamin D / Q000627:therapeutic use*
D016207:Cytokines; D014807:Vitamin D; D002117:Calcitriol