A review of behavioral treatments used for Lesch-Nyhan syndrome.
Lesch-Nyhan syndrome is a genetic disorder resulting in hyperuricemia, choreoathetosis, mental retardation, and self-mutilation. The most salient feature of this disorder is the self-injurious behavior (SIB). Although the utility of behavioral interventions with SIB has been well documented, behavioral interventions with Lesch-Nyhan syndrome have been limited in number and long-term success. This article reviews the behavioral treatments that have been used in treating individuals with Lesch-Nyhan syndrome and discusses the strengths and weaknesses of these methods. Suggestions for future directions in the use of behavioral interventions for controlling SIB in Lesch-Nyhan syndrome are provided.
Olson
L
L
University of South Carolina, USA.
Houlihan
D
D
D001521:Behavior Therapy / Q000379:methods*; D002648:Child; D005108:Extinction, Psychological; D006801:Humans; D007926:Lesch-Nyhan Syndrome / Q000523:psychology* / Q000628:therapy*; D008960:Models, Psychological; D012054:Reinforcement, Psychology; D012149:Restraint, Physical / Q000379:methods*; D016728:Self-Injurious Behavior / Q000517:prevention & control*