[The mechanisms for the decrease in gastric motor-evacuatory function after performing a vagotomy].
In experiment on white rats in was established that after the truncal vagotomy performance in the stress gastric ulcer the lowering of the serotonin and histamine blood content was noted as well as the disorder of ratio of their concentration in gastric wall. Insufficiency of serotonin causes the disorder of gastric motor-evacuation function after the operation. Administration in postoperative period of serotonin adipinate had promoted the raising of serotonin concentration in blood and gastric tissues, histamine level lowering, enhancement of serotonin/histamine ratio.
Lupal'tsov
V I
VI
Iagniuk
A I
AI
D000272:Adipates / Q000494:pharmacology; D000818:Animals; D004195:Disease Models, Animal; D005746:Gastric Emptying / Q000187:drug effects / Q000502:physiology*; D006632:Histamine / Q000097:blood; D008297:Male; D010437:Peptic Ulcer / Q000097:blood / Q000601:surgery; D011184:Postoperative Period; D011708:Pylorus / Q000601:surgery; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000031:analogs & derivatives / Q000097:blood / Q000494:pharmacology; D013312:Stress, Physiological / Q000097:blood / Q000601:surgery; D013997:Time Factors; D015167:Vagotomy, Truncal / Q000009:adverse effects*
D000272:Adipates; C059902:serotonin adipinate; D012701:Serotonin; D006632:Histamine