title: Polymer-supported reagents and catalysts: recent advances in synthetic applications.
abstract: The current surge in parallel array synthesis for the production of small molecule libraries has generated keen interest in the application of solid-supported reagents and catalysts in solution-phase chemistry. The strategy assimilates the advantages of product isolation and purification of solid-phase organic synthesis with the flexible choice of chemistry from the vast repertoire of solution-phase organic reactions. This review summarizes the significant recent advances in the application of polymer-bound reagents and catalysts in solution-phase synthesis of organic molecules. Multi-step reaction sequences employing sequential use of polymer-supported reagents are also discussed. In view of the earlier review publications on this topic, only the recent literature covering 1998 and 1999 is included.
authors.affiliation: Argonaut Technologies, San Carlos, CA 94070, USA. sbhattacharyya@argotech.com
authors.forename: S
authors.initials: S
authors.lastname: Bhattacharyya
mesh_terms: D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D007202:Indicators and Reagents / Q000737:chemistry; D008956:Models, Chemical; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*; D012116:Resins, Plant / Q000737:chemistry
chemical_list: D007202:Indicators and Reagents; D011108:Polymers; D012116:Resins, Plant