Healing of burns after treatment with 670-nanometer low-power laser light.
Recent investigations have reported contradictory results on the influence of low-power laser light on wound healing. Low-power laser with a power output of 250 mW and an emitted laser light of 670 nm have been insufficiently investigated to date. The effect of a 250-mW/670-nm laser light on the healing of burning wounds in rats was investigated. Thirty rats were burned on both flanks. One wound was irradiated with 670-nm laser light (2 J/cm2), whereas the other side remained untreated. Macroscopic evaluation of the wounds was performed daily; 10, 20, and 30 days after burning, 10 rats were killed and the wounds histologically evaluated. Neither macroscopic nor histologic examination of the irradiated wound showed accelerated wound healing when compared with control wounds. In the present study, irradiation of burns with a 250-mW/670-nm laser light produced no beneficial effects on wound-healing processes.
Schlager
A
A
Department of Anesthesia and General Intensive Care Medicine, Leopold Franzens University of Innsbruck, Austria. andreas.schlager@uibk.ac.at
Oehler
K
K
Huebner
K U
KU
Schmuth
M
M
Spoetl
L
L
D000818:Animals; D002056:Burns / Q000473:pathology / Q000532:radiotherapy*; D004307:Dose-Response Relationship, Radiation; D053685:Laser Therapy; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000473:pathology / Q000528:radiation effects; D014945:Wound Healing / Q000528:radiation effects*