title: Spatial distribution functions as a tool in the analysis of ribonucleic acids hydration--molecular dynamics studies.
abstract: The spatial distribution functions (SDFs) determined as three-dimensional density distribution of hydrogen and oxygen atoms of water in a local coordinate system linked with RNA molecule are used to study details of the spatial structure of aqueous solution around selected parts of RNA duplexes: r(CGCGCG)2 and 2'-O-Me(CGCGCG)2. The influence of the 2'-O-methylation on the hydration pattern of RNA helical fragments is visualized at the atomic level.
authors.affiliation: Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań. kasiak@ibch.poznan.pl
authors.forename: K
authors.initials: K
authors.lastname: Kulińska
authors.forename: T
authors.initials: T
authors.lastname: Kuliński
authors.forename: A
authors.initials: A
authors.lastname: Lyubartsev
authors.forename: A
authors.initials: A
authors.lastname: Laaksonen
authors.forename: R W
authors.initials: RW
authors.lastname: Adamiak
mesh_terms: D020029:Base Pairing; D017665:Hydroxyl Radical; D008745:Methylation; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D010100:Oxygen / Q000737:chemistry; D012313:RNA / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D014867:Water; D017665:Hydroxyl Radical; D012313:RNA; D010100:Oxygen