title: Augmentative treatment of chronic deafferentation pain syndromes after peripheral nerve lesions.
abstract: Deafferentation pain syndromes developing after peripheral nerve lesions are difficult to treat. According to the follow-up (mean: 39.5 months) of 6 patients suffering from causalgic pain we will present our method of augmentative therapy in chronic neuropathic pain caused by peripheral nerve lesions, i.e., peripheral nerve stimulation (PNS), spinal cord stimulation (SCS) and chronic intrathecal opioid infusion. None of the patients showed intraoperative or follow-up complications. Evaluated by visual analogue scales all patients reported a good to excellent pain relief (75-100%). (1) Regarding the favourable long-term results of PNS, this method should be considered in cases of mononeuropathic pain syndromes. (2) Neuropathic pain syndromes which are not assignable to a singular nerve lesion, can often be managed effectively by SCS. (3) In contrast to the widespread opinion, deafferentation pain syndromes of central or peripheral origin can be treated satisfactorily by intrathecal opiate administration.
authors.affiliation: Neurosurgical Department, University of Cologne, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Ebel
authors.forename: A
authors.initials: A
authors.lastname: Balogh
authors.forename: M
authors.initials: M
authors.lastname: Volz
authors.forename: N
authors.initials: N
authors.lastname: Klug
mesh_terms: D000328:Adult; D000368:Aged; D000701:Analgesics, Opioid / Q000627:therapeutic use; D002422:Causalgia / Q000628:therapy*; D003131:Combined Modality Therapy; D004599:Electric Stimulation Therapy; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D008875:Middle Aged; D017933:Peripheral Nervous System / Q000502:physiology; D010523:Peripheral Nervous System Diseases / Q000628:therapy*; D011379:Prognosis; D013116:Spinal Cord / Q000502:physiology; D016896:Treatment Outcome
chemical_list: D000701:Analgesics, Opioid