[Lipid peroxidation and Ca2+,Mg2+-ATPase activity of uterine myocyte cell membranes in hyperplastic processes].
It was shown that intensity of endogenous, Feascorbic- and NADPH-dependent lipids peroxidation in the border zone was 2-2.5-fold as higher as in the normal tissues. In the central part of the knot the intensity of all these above mentioned forms of lipids peroxidations is much lower than in the normal tissue. Plasma membrane Ca2+, Mg(2+)-ATPase activity of the border zone of myomic knot is 2-fold as lower as in the normal tissue. 10(-6) M malonal dialdegide decreases the Ca2+, Mg(2+)-ATPase activity up to the level of this enzyme activity in the border zone of myoma knot.
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A.A. Bogomolets State Medical University of Ukraine, Kyiv.
D017301:Ca(2+) Mg(2+)-ATPase / Q000378:metabolism*; D002462:Cell Membrane / Q000201:enzymology / Q000378:metabolism; D004714:Endometrial Hyperplasia / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation; D009130:Muscle, Smooth / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D011247:Pregnancy
D017301:Ca(2+) Mg(2+)-ATPase