Advances in diagnosis and management of herpetic uveitis.
Herpetic eye disease is common and is frequently associated with intraocular inflammation or uveitis. Despite recent advances in measuring anti-herpes virus antibodies and viral DNA in ocular fluids, diagnosis remains largely clinical. The two more common syndromes include anterior uveitis, often associated with keratitis, and the acute retinal necrosis (ARN) syndrome. Treatment is complex and requires careful monitoring to provide the appropriate balance of antiviral medication and corticosteroids. Long-term prophylaxis with oral antiviral agents may be required in selected patients to help prevent the vision-compromising complications associated with recurrences.
Gaynor
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BD
Francis I. Proctor Foundation, UCSF, Medical Center 94143, USA.
Margolis
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TP
Cunningham
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ET
D000998:Antiviral Agents / Q000627:therapeutic use*; D003941:Diagnostic Techniques, Ophthalmological; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology; D005938:Glucocorticoids / Q000627:therapeutic use*; D006566:Herpesviridae Infections / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology; D006801:Humans; D014605:Uveitis / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology
D000998:Antiviral Agents; D005938:Glucocorticoids