An efficient diamine.copper complex-catalyzed coupling of arylboronic acids with imidazoles
[formula: see text] A novel diamine.copper complex-catalyzed intermolecular coupling of arylboronic acids (1) with imidazoles (3) is described. In the presence of a catalytic amount of [Cu(OH).TMEDA]2Cl2 (2), arylboronic acids (1) react smoothly with imidazoles (3) in dichloromethane at room temperature to give a variety of N-arylimidazoles (4) in good to excellent yields.
Collman
JP
Department of Chemistry, Stanford University, California 94305-5080, USA. jpc@chem.stanford.edu
Zhong
M