title: [MRI spectroscopy, T2 relaxometry, and postoperative prognosis in cryptogenic temporal lobe epilepsy].
abstract: The preoperative localization of pharmaco-resistant focal epilepsies before surgery and the prognosis concerning seizure outcome are both of importance. In addition to conventional MRI diagnostics for the detection of small epileptogenic lesions, proton magnetic resonance spectroscopic imaging (HMR spectroscopy) can be useful for assessing the bilaterality of pathological changes in cryptogenic temporal lobe epilepsies. The technique and findings of HMR spectroscopy are reported in patients with cryptogenic temporal lobe epilepsies. The findings indicate that chemical shift imaging (CSI) investigations of the ipsilateral and contralateral hemispheres provide important information for the prediction of seizure outcome after epilepsy surgery.
authors.affiliation: Neurologische Klinik, Universität Erlangen-Nürnberg.
authors.forename: H
authors.initials: H
authors.lastname: Stefan
authors.forename: E
authors.initials: E
authors.lastname: Pauli
authors.forename: K E
authors.initials: KE
authors.lastname: Eberhardt
authors.forename: I
authors.initials: I
authors.lastname: Schäfer
authors.forename: P
authors.initials: P
authors.lastname: Hopp
authors.forename: W J
authors.initials: WJ
authors.lastname: Huk
mesh_terms: D000328:Adult; D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D001921:Brain / Q000378:metabolism / Q000473:pathology* / Q000601:surgery*; D016022:Case-Control Studies; D002794:Choline / Q000378:metabolism; D004292:Dominance, Cerebral; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D019906:Nuclear Magnetic Resonance, Biomolecular; D011379:Prognosis; D016896:Treatment Outcome
chemical_list: D001224:Aspartic Acid; C000179:N-acetylaspartate; D002794:Choline