Role of tumour markers in monitoring epithelial ovarian cancer.
Currently the only tumour marker to have a well-defined and validated role in the management of ovarian cancer is CA125. Changes in the level of CA125 can be used as a reliable indication of response or progression according to various criteria, but it does not yet have a clear place in diagnosis or prognosis. Its value as part of a screening tool and during routine follow-up remain the subject of ongoing trials. Other markers remain experimental and do not have a well-defined contribution to make at present.
Meyer
T
T
Department of Medical Oncology, Mount Vernon Hospital, Northwood, Middlesex, UK.
Rustin
G J
GJ
D014408:Biomarkers, Tumor / Q000032:analysis*; D018394:CA-125 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D008991:Monitoring, Physiologic; D010051:Ovarian Neoplasms / Q000097:blood / Q000175:diagnosis / Q000473:pathology*; D012008:Recurrence
D014408:Biomarkers, Tumor; D018394:CA-125 Antigen