Earliest pages of bioinformatics.
This review is a brief outline of the chronology and essence of early events in bioinformatics, covering the period from 1869 (discovery of DNA by Miescher) to 1980-1981 (beginning of massive sequencing). For the purpose of this review, bioinformatics is understood as a chapter of molecular biology dealing with the amino acid and nucleotide sequences and with the information they carry.
Trifonov
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Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel. edward.trifonov@weizmann.ac.il
D000818:Animals; D003062:Codon; D019295:Computational Biology / Q000266:history*; D005786:Gene Expression Regulation; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D014176:Protein Biosynthesis; D012326:RNA Splicing; D012106:Research / Q000266:history; D017421:Sequence Analysis / Q000266:history
D003062:Codon