[The morphogenesis and pathogenesis of a metadiaphyseal infarct of the long bones in different types of ischemia].
In experiment on the animal's bones the various kinds of ischemia was simulated (obturational, compressive, traumatic) it was established that the central mechanism of the bone infarction pathogenesis is irreversible blockade of microcirculatory bed by cellular aggregates and microthrombi. The most extended and constant infarction occurs in embolization of the main nourishing artery and in osteotomy of diaphysis with the bone marrow intersection and the periosteum detachment on the ends of fragments.
Grigorovskiĭ
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D000208:Acute Disease; D000818:Animals; D018483:Diaphyses / Q000098:blood supply / Q000473:pathology; D004195:Disease Models, Animal; D005269:Femur / Q000098:blood supply* / Q000473:pathology; D007238:Infarction / Q000209:etiology* / Q000473:pathology; D007511:Ischemia / Q000150:complications / Q000209:etiology* / Q000473:pathology; D011817:Rabbits; D013977:Tibia / Q000098:blood supply* / Q000473:pathology; D013997:Time Factors