High-dose systemic corticosteroids can arrest recurrences of severe mucocutaneous erythema multiforme.
We treated two children with a total of five recurrences of erythema multiforme major with pulsed dose, systemic corticosteroid therapy on an open basis, and report herein the beneficial effects of this regime. We mean to further reevaluate this therapy on a controlled study basis.
Martinez
A E
AE
Department of Dermatology, Great Ormond Street Hospital for Children, London, England.
Atherton
D J
DJ
D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D004892:Erythema Multiforme / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D055502:Secondary Prevention; D012720:Severity of Illness Index; D016896:Treatment Outcome
D005938:Glucocorticoids; D008775:Methylprednisolone