title: Pediatric renal cell carcinomas: where do they fit in the new histologic classification of renal cell carcinoma?
abstract: Genetic, immunohistochemical, and histologic data has led to the reclassification of renal cell carcinoma in the last decade. Recent studies suggest that renal cell carcinomas in children and young adults may represent a distinct group of tumors. These tumors have unique genetic findings (most commonly t(x;1)(p11:q21)), a predominantly papillary architecture, numerous calcifications, granular cytoplasm, and a possible relationship with neuroblastoma.
authors.affiliation: Department of Pathology, Baptist Hospital of Miami, Florida, USA.
authors.forename: A A
authors.initials: AA
authors.lastname: Renshaw
mesh_terms: D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000473:pathology; D015415:Biomarkers; D002292:Carcinoma, Renal Cell / Q000145:classification / Q000235:genetics / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D007633:Keratins / Q000032:analysis; D007680:Kidney Neoplasms / Q000145:classification / Q000235:genetics / Q000473:pathology*; D018396:Mucin-1 / Q000032:analysis; D009447:Neuroblastoma / Q000473:pathology; D014746:Vimentin / Q000032:analysis
chemical_list: D015415:Biomarkers; C400901:CAM 5.2 antigen; D018396:Mucin-1; D014746:Vimentin; D007633:Keratins