title: Drug-induced and traumatic nail problems in the haemophilias.
abstract: Many persons with haemophilia suffer from HIV and receive highly active antiretroviral therapy. Three patients received indinavir and required surgery due to ingrown toenails. Two patients suffered from a traumatic subungual haematoma. The treatment protocol is described whereby the pressure exerted onto the germinal layer and the nail bed is relieved in order to alleviate pain and nail matrix damage.
authors.affiliation: Department of Orthopaedic Rehabilitation, Tel-Hashomer Hospital, Tel-Hashomer, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Heim
authors.forename: J
authors.initials: J
authors.lastname: Schapiro
authors.forename: M
authors.initials: M
authors.lastname: Wershavski
authors.forename: U
authors.initials: U
authors.lastname: Martinowitz
mesh_terms: D000328:Adult; D017789:Granuloma, Pyogenic / Q000139:chemically induced / Q000209:etiology / Q000473:pathology; D017320:HIV Protease Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D006406:Hematoma / Q000139:chemically induced / Q000209:etiology / Q000473:pathology; D006467:Hemophilia A / Q000150:complications* / Q000188:drug therapy / Q000821:virology; D002836:Hemophilia B / Q000150:complications / Q000188:drug therapy / Q000821:virology; D006801:Humans; D019469:Indinavir / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D009260:Nail Diseases / Q000139:chemically induced / Q000209:etiology* / Q000473:pathology; D009262:Nails / Q000098:blood supply / Q000293:injuries / Q000473:pathology*; D009263:Nails, Ingrown / Q000139:chemically induced / Q000209:etiology / Q000473:pathology; D019966:Substance-Related Disorders / Q000150:complications* / Q000473:pathology
chemical_list: D017320:HIV Protease Inhibitors; D019469:Indinavir