title: In-Line Proximity Effects in Extended 7-Azanorbornanes. 2. A Major Reduction of N-Inversion Barriers in Symmetrically Flanked Systems.
abstract: Through-space compression effects from a pair of flanking (sentinel) groups X are shown to cause a flattening of the bridging nitrogen in symmetrically fused 7-azanorbornanes which is evaluated by a substantial reduction of the nitrogen inversion barrier as measured by low-temperature (1)H NMR spectroscopy. This effect is attributed to destabilization of the ground state of the amine.
authors.affiliation: Department of Chemistry, University of Leicester, Leicester, United Kingdom, LE1 7RH, and Centre for Molecular Architecture, Central Queensland University, Rockhampton, Queensland, Australia, 4700.
authors.initials: JR
authors.lastname: Malpass
authors.initials: DN
authors.lastname: Butler
authors.initials: MR
authors.lastname: Johnston
authors.initials: ML
authors.lastname: Hammond
authors.initials: RN
authors.lastname: Warrener