title: A child with neurofibromatosis-1 and a lumbar epidural arteriovenous malformation.
abstract: A 10-year-old child with neurofibromatosis-1 was evaluated for progressive lumbar scoliosis, back pain, and foot numbness. Magnetic resonance imaging showed several lumbar intraspinal and extraspinal masses consistent with neurofibromas. The mass at L3-L5 compressed the thecal sac and was thought to be the source of the symptoms. On operative exploration, a lumbar epidural arteriovenous malformation was found, which was removed in its entirety. The child's back pain and foot numbness resolved. Epidural arteriovenous malformations in patients with neurofibromatosis-1 are rare and have been reported only in the cervical spine. Our finding of a lumbar epidural arteriovenous malformation in a child with neurofibromatosis-1 demonstrates that vascular anomalies can be present throughout the spine of patients with neurofibromatosis-1 and should be considered in the differential diagnosis of any neurofibromatosis-1-related epidural mass.
authors.affiliation: Pritzker School of Medicine, University of Chicago Children's Hospital, Illinois 60637, USA.
authors.forename: M
authors.initials: M
authors.lastname: Nadig
authors.forename: I
authors.initials: I
authors.lastname: Munshi
authors.forename: M P
authors.initials: MP
authors.lastname: Short
authors.forename: J H
authors.initials: JH
authors.lastname: Tonsgard
authors.forename: C
authors.initials: C
authors.lastname: Sullivan
authors.forename: D M
authors.initials: DM
authors.lastname: Frim
mesh_terms: D001165:Arteriovenous Malformations / Q000150:complications / Q000473:pathology*; D001416:Back Pain / Q000209:etiology; D002648:Child; D005260:Female; D005528:Foot / Q000294:innervation; D006801:Humans; D006987:Hypesthesia / Q000209:etiology; D008161:Lumbosacral Region / Q000098:blood supply; D008279:Magnetic Resonance Imaging; D009456:Neurofibromatosis 1 / Q000150:complications*; D012600:Scoliosis / Q000209:etiology; D013116:Spinal Cord / Q000098:blood supply*