title: Reversible frontal lobe syndrome associated with influenza virus infection in children.
abstract: Two patients, a 3-year-old female and a 1-year-old female, both with a focal encephalopathic process associated with influenza A virus infection, are reported. Both children had neuropsychologic signs suggesting frontal and limbic dysfunction, without disturbances of consciousness or motor function, and had good recoveries. The results of single-photon emission computed tomography and electroencephalography support the finding of reversible impairment of the frontal and limbic areas. Focal reversible encephalopathy has rarely been reported in association with influenza virus infection, although it often provokes diffuse encephalopathies, with a poor prognosis.
authors.affiliation: Department of Pediatrics, Musashino Red Cross Hospital, Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Sato
authors.forename: S
authors.initials: S
authors.lastname: Kumada
authors.forename: T
authors.initials: T
authors.lastname: Koji
authors.forename: M
authors.initials: M
authors.lastname: Okaniwa
mesh_terms: D002675:Child, Preschool; D004569:Electroencephalography; D018792:Encephalitis, Viral / Q000000981:diagnostic imaging*; D005260:Female; D005625:Frontal Lobe / Q000821:virology*; D006801:Humans; D007223:Infant; D007251:Influenza, Human / Q000000981:diagnostic imaging*; D009975:Orthomyxoviridae; D011379:Prognosis; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019690:Technetium Tc 99m Exametazime