Organelle division: Self-assembling GTPase caught in the middle.
Recent findings indicate that the dynamin GTPase helps to divide animal and fungal mitochondria, and that the tubulin-like FtsZ GTPase is involved in division of, not only most bacteria, but also chloroplasts and probably mitochondria of unicellular eukaryotes.
Margolin
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Department of Microbiology and Molecular Genetics, University of Texas-Houston Medical School, Houston, 77030, USA. margolin@utmmg. med.uth.tmc.edu
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D029681:Arabidopsis Proteins; D001426:Bacterial Proteins / Q000378:metabolism; D002455:Cell Division; D002736:Chloroplasts / Q000502:physiology; D003598:Cytoskeletal Proteins; D034281:Dynamins; D029968:Escherichia coli Proteins; D020558:GTP Phosphohydrolases / Q000378:metabolism; D019204:GTP-Binding Proteins / Q000378:metabolism*; D008928:Mitochondria / Q000502:physiology; D010940:Plant Proteins / Q000378:metabolism*
D029681:Arabidopsis Proteins; D001426:Bacterial Proteins; D003598:Cytoskeletal Proteins; D029968:Escherichia coli Proteins; C095113:FTSZ protein, Arabidopsis; C071525:FtsZ protein, Bacteria; D010940:Plant Proteins; D000251:Adenosine Triphosphatases; D020558:GTP Phosphohydrolases; D019204:GTP-Binding Proteins; C072069:MinD protein, E coli; D034281:Dynamins