title: [Acute asthmatic crisis in children].
abstract: Acute asthma attack in children is an attack responsible for life-threatening acute respiratory distress with partial or no response to bronchodilator drugs. The severity of the episode needs to be quickly evaluated. This presupposes a perfect knowledge of the clinical signs of severity. Treatment is urgent and first based on the administration of high doses of inhaled short-acting beta 2-agonists. In the more obstructed children, anti-cholinergic drugs can be added to nebulized beta 2-agonists. Because of their delayed effect, systemic steroids require an early prescription. Symptomatic treatments are: urgent hospitalization, oxygen if needed, proper hydratation. Continuous nebulization or intravenous perfusion of beta 2-agonists are prescribed with cardiac monitoring when no objective improvement is noted. Admission into the pediatric intensive care unit when bronchial obstruction continues will permit the association of bronchodilator drugs and the proposal of mechanical ventilation if needed. When the episode is resolved, a prophylactic treatment using inhaled corticosteroids must be prescribed. Clinical and spirometric follow-up has to be organized, and the patient and his/her family have to be educated.
authors.affiliation: Service de médecine infantile, CHU Timone-Enfants, Marseille, France.
authors.forename: J C
authors.initials: JC
authors.lastname: Dubus
authors.forename: A C
authors.initials: AC
authors.lastname: Bodiou
authors.forename: C
authors.initials: C
authors.lastname: Buttin
authors.forename: T
authors.initials: T
authors.lastname: Jouglet
authors.forename: N
authors.initials: N
authors.lastname: Stremler
authors.forename: L
authors.initials: L
authors.lastname: Mély
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D001993:Bronchodilator Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D004630:Emergencies; D006801:Humans; D007223:Infant; D012121:Respiration, Artificial; D012138:Respiratory Therapy; D013224:Status Asthmaticus / Q000175:diagnosis / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones; D000318:Adrenergic beta-Agonists; D001993:Bronchodilator Agents; D018680:Cholinergic Antagonists