[Cerebrospinal fluid cytology of acute viral encephalitis and meningitis].
Using cytological examination, the cerebrospinal fluid(CSF) of 98 patients with acute viral encephalitis was investigated. We found 81.4% activated lymphocytes and 5.8% plasma cells in CSF in the first week. In addition, various lymphoid features were disclosed in association: mitosis, binucleation, abnormal nuclear lobulation, Russell bodies, and morula in plasma cells. These cellular changes specifically existed in CSF of acute viral encephalitis, which were helpful to distinguish the said disease from tuberculous melitis and multiple sclerosis.
Xiao
B
B
Department of Neurology, Xiangya Hospital, Hunan Medical University, Changsha.
Peng
Y
Y
Xiao
L
L
Yang
H
H
Xiao
J
J
Li
J
J
Liang
J
J
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D002555:Cerebrospinal Fluid / Q000166:cytology*; D002648:Child; D002675:Child, Preschool; D018792:Encephalitis, Viral / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008587:Meningitis, Viral / Q000134:cerebrospinal fluid*; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology