Immunological evaluation of human immunodeficiency virus infected individuals by flow cytometry.
Human immunodeficiency virus (HIV) infection heavily compromises the immune system. The decrease of the T cell CD4+ subset along the evolution to acquired immunodeficiency syndrome has been considered as a hallmark of HIV infection. In this paper we review some aspects of the immunopathology of HIV infection and discuss the importance of the flow cytometry for the evaluation of the T lymphocyte subsets in the follow-up of HIV infected children and adults, and for the monitoring of the immune reconstitution upon antiretroviral therapy.
Neves
I
I
Laboratório de Aids e Imunologia Molecular, Departamento de Imunologia, Instituto Oswaldo Cruz, Rio de Janeiro, Brasil.
Morgado
M
M
D000293:Adolescent; D000328:Adult; D017209:Apoptosis; D015415:Biomarkers / Q000097:blood; D015496:CD4-Positive T-Lymphocytes; D018414:CD8-Positive T-Lymphocytes; D002648:Child; D005434:Flow Cytometry / Q000379:methods*; D005500:Follow-Up Studies; D015658:HIV Infections / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D018655:Lymphocyte Count / Q000379:methods
D015415:Biomarkers