title: [Primary adenocarcinoma of the jejunum arising in the anastomotic loop of a Roux-en-Y esophago-jejunostomy: a case report].
abstract: The authors report a case of primary adenocarcinoma arising in the jejunal limb of a Roux-en-Y esophago-jejunostomy in a 76-years-old Caucasian woman. She was affected by esophageal achalasia and in another surgical department underwent gastric resection for adenocarcinoma 6 months before admission. A total gastrectomy performed was due to severity of achalasia symptoms conditioning a high degree of malnutrition. Two years after discharge the patient underwent surgery for total dysphagia, epigastric pain and inexorable weight loss. Histological response was adenocarcinoma of the long arm of Roux-en-y loop. Primary malignancies of the jejunum and ileum are extremely rare and many pathogenetic hypotheses were done but none of them received clinical or experimental demonstration. Symptoms are not specific and diagnosis is difficult and late, x-rays and endoscopy leading to it, US, CT and MNR are useful for differential diagnosis and staging. Prognosis is severe. Surgical therapy is large resection, if possible, but often it is only palliative.
authors.affiliation: Divisione di Chirurgia Generale A, Ospedale Maggiore C. A. Pizzardi, Bologna.
authors.forename: A
authors.initials: A
authors.lastname: Lazzari
authors.forename: F
authors.initials: F
authors.lastname: Talarico
authors.forename: R
authors.initials: R
authors.lastname: Armaroli
authors.forename: G
authors.initials: G
authors.lastname: Garulli
authors.forename: M
authors.initials: M
authors.lastname: Spangaro
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000368:Aged; D000713:Anastomosis, Roux-en-Y; D003937:Diagnosis, Differential; D004946:Esophagostomy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007580:Jejunal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D007582:Jejunostomy; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery