title: Highly stereospecific, palladium-catalyzed cross-coupling of alkenylsilanols
abstract: [reaction: see text] Alkenylsilanols bearing methyl ((E)-1 and (Z)-1) or isopropyl ((E)-2 and (Z)-2)) substituents are converted to disubstituted alkenes by a palladium(0)-catalyzed cross-coupling reaction with aryl or vinyl iodides in the presence of tetrabutylammonium fluoride or hydroxide. Yields and stereoselectivities are generally high, and the reaction is compatible with a wide range of functional groups.
authors.affiliation: Department of Chemistry, University of Illinois, Urbana 61801, USA. denmark@scs.uiuc.edu
authors.initials: SE
authors.lastname: Denmark
authors.initials: D
authors.lastname: Wehrli