title: Generalized annular borderline tuberculoid leprosy and update in management of Hansen's disease.
abstract: We describe a patient with widespread borderline tuberculoid leprosy and significant peripheral nerve involvement. Despite the presence of widespread lesions, Fite stains and polymerase chain reaction studies were initially negative. We discuss the diagnosis and treatment of leprosy including recent changes in treatment regimens and duration.
authors.affiliation: Department of Dermatology, Wilford Hall Medical Center, Lackland AFB, San Antonio, Texas, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Young
authors.forename: R T
authors.initials: RT
authors.lastname: Gilson
authors.forename: D M
authors.initials: DM
authors.lastname: Elston
mesh_terms: D000368:Aged; D002991:Clofazimine / Q000627:therapeutic use; D004269:DNA, Bacterial / Q000032:analysis; D003622:Dapsone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D007917:Leprostatic Agents / Q000627:therapeutic use*; D015439:Leprosy, Borderline / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology; D015441:Leprosy, Tuberculoid / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology; D008297:Male; D009166:Mycobacterium leprae / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D012293:Rifampin / Q000627:therapeutic use
chemical_list: D004269:DNA, Bacterial; D007917:Leprostatic Agents; D003622:Dapsone; D002991:Clofazimine; D012293:Rifampin