Human immunodeficiency virus-related primary cutaneous aspergillosis.
A 31-year-old Caucasian man with AIDS developed a crusted violaceous plaque under adhesive tape near a central venous catheter insertion site. Histological examination demonstrated a ruptured hair follicle containing collections of fungal hyphae typical of Aspergillus spp. A culture of the biopsy material grew Aspergillus fumigatus. The patient responded to removal of the catheter and the occlusive dressing, in addition to itraconazole therapy. Aspergillosis must be considered in the differential diagnosis of cutaneous lesions in human immunodeficiency virus-infected patients, in particular when the lesion occurs under adhesive tape or an occlusive dressing.
Stanford
D
D
Department of Dermatology, Royal Newcastle Hospital, New South Wales, Australia. duncan_stanford@bigpond.com
Boyle
M
M
Gillespie
R
R
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis*; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis*; D001232:Aspergillus fumigatus / Q000254:growth & development; D002405:Catheterization, Central Venous / Q000295:instrumentation; D003881:Dermatomycoses / Q000175:diagnosis*; D006678:HIV; D018859:Hair Follicle / Q000382:microbiology; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D009779:Occlusive Dressings / Q000382:microbiology
D000935:Antifungal Agents; D017964:Itraconazole