CD56 expression in a case of primary cutaneous CD30+ anaplastic large cell lymphoma.
We describe clinicopathological features of an unusual case of CD30+/CD56+ T-cell lymphoma in a 58-year-old Korean man who presented with disseminated nodules, papules and hyperpigmented patches. Coexpression of CD30 and CD56 in T-cell lymphoma is very rare. Our patient did not respond to an intensive chemotherapy regimen, in contrast to the previously reported cases of primary cutaneous CD30+ anaplastic large cell lymphoma. Coexpression of CD56 might therefore identify a subset of CD30+ lymphomas with more aggressive features.
Chang
S E
SE
Departments of Dermatology and Pathology, Asan Medical Center, College of Medicine, University of Ulsan, 388-1 Poongnap-Dong, Songpa-Gu, Seoul 138-736, Korea.
Park
I J
IJ
Huh
J
J
Choi
J H
JH
Sung
K J
KJ
Moon
K C
KC
Koh
J K
JK
D000951:Antigens, Neoplasm / Q000032:analysis; D001706:Biopsy; D019002:CD56 Antigen / Q000032:analysis*; D006801:Humans; D017730:Ki-1 Antigen / Q000032:analysis*; D017728:Lymphoma, Large-Cell, Anaplastic / Q000276:immunology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D012878:Skin Neoplasms / Q000276:immunology* / Q000473:pathology
D000951:Antigens, Neoplasm; D019002:CD56 Antigen; D017730:Ki-1 Antigen