title: T cell-mediated paraneoplastic ganglionitis--an autopsy case.
abstract: A 57-year-old woman presented with subacute sensory, ataxic neuronopathy. Clinical investigation revealed a right-sided non-small-cell lung cancer. Serum investigation for specific antineuronal antibodies was negative. Histology showed T lymphocytic infiltrates in dorsal root ganglia. The observed histological pattern is similar to that described in antibody-positive cases. Thus, these findings suggest similar pathways in specific antineuronal antibody-negative and -positive cases of paraneoplastic subacute sensory neuronopathy.
authors.affiliation: Ludwig Boltzmann Institut für Neuroonkologie, Linz, Austria. marcus.drlicek@wj.lkh.ooe.gv.at
authors.forename: M
authors.initials: M
authors.lastname: Drlicek
authors.forename: A
authors.initials: A
authors.lastname: Bodenteich
authors.forename: U
authors.initials: U
authors.lastname: Setinek
authors.forename: G
authors.initials: G
authors.lastname: Tucek
authors.forename: S
authors.initials: S
authors.lastname: Urbanits
authors.forename: W
authors.initials: W
authors.lastname: Grisold
mesh_terms: D001323:Autoantibodies / Q000276:immunology; D051959:ELAV Proteins; D017809:Fatal Outcome; D005260:Female; D005727:Ganglia, Spinal / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000032:analysis; D020364:Paraneoplastic Polyneuropathy / Q000276:immunology / Q000473:pathology*; D016601:RNA-Binding Proteins / Q000032:analysis; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D051959:ELAV Proteins; D009419:Nerve Tissue Proteins; D016601:RNA-Binding Proteins