Reductive cleavage of N-O bonds using Samarium(II) iodide in a traceless release strategy for solid-phase synthesis
A strategy for making amides and ureas using a polymer-supported hydroxylamine resin as a traceless linker is described. The cleavage of the linker by samarium(II) iodide is reported for the first time.
Myers
RM
University Chemical Laboratories, Lensfield Road, Cambridge, CB2 1EW, England.
Langston
SP
Conway
SP
Abell
C