[Humoral reaction to Bordetella pertussis antigens: pertussis toxin, filamentous hemagglutinin and lipopolysaccharide in children with clinical symptoms of whooping cough. I. Antibody level for B pertussis antigens in children without respiratory tract infection symptoms].
The aim of the first part of this study was to determine antibody level to pertussis toxin, filamentous hemagglutinin and endotoxin of B. pertussis in children without symptoms of respiratory tract infection. The serum samples obtained from 276 children (age range: 6 weeks-16 years) were examined using indirect hemagglutination and ELISA tests. Normal antibody levels to 3 B. pertussis antigens were determined for 95% of the serum samples as the upper cut-off levels depending on children age. Very high level of IgG antibodies to B.perussis antigens was observed in the control population. The lowest antibody level was found in IgA class to pertussis toxin and lipopolysaccharide. It was also established that the IgM level to 3 B. pertussis antigens was rising together with children age.
Chodorowska
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Zakład Bakteriologii PZH w Warszawie.
D018829:Adhesins, Bacterial / Q000276:immunology*; D000293:Adolescent; D000375:Aging / Q000276:immunology; D000907:Antibodies, Bacterial / Q000032:analysis*; D000917:Antibody Formation / Q000276:immunology; D001886:Bordetella pertussis / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D006388:Hemagglutinins / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007223:Infant; D008070:Lipopolysaccharides / Q000276:immunology*; D037342:Pertussis Toxin; D012016:Reference Values; D010566:Virulence Factors, Bordetella / Q000276:immunology*
D018829:Adhesins, Bacterial; D000907:Antibodies, Bacterial; D006388:Hemagglutinins; D007074:Immunoglobulin G; D008070:Lipopolysaccharides; D010566:Virulence Factors, Bordetella; C065273:filamentous hemagglutinin adhesin, Bordetella pertussis; D037342:Pertussis Toxin