title: Morphometric and mechanical evaluation of titanium implant integration: comparison of five surface structures.
abstract: Achieving a stable bone-implant interface is an important factor in the long-term outcome of joint arthroplasty. In this study, we employed an ovine bicortical model to compare the bone-healing response to five different surfaces on titanium alloy implants: grit blasted (GB), grit blasted plus hydroxyapatite (50 microm thick) coating (GBHA), Porocoat(R) (PC), Porocoat(R) with HA (PCHA) and smooth (S). Push-out testing, histology, and backscatter scanning electron microscope (SEM) imaging were employed to assess the healing response at 4, 8, and 12 weeks. Push-out testing revealed PC and PCHA surfaces resulted in significantly greater mechanical fixation over all other implant types at all time points (p <.05). HA coating on the grit-blasted surface significantly improved fixation at 8 and 12 weeks (p <.05). The addition of HA onto the porous coating did not significantly improve fixation in this model. Quantification of ingrowth/ongrowth from SEM images revealed that HA coating of the grit-blasted surfaces resulted in significantly more ongrowth at 4 weeks (p <.05).
authors.affiliation: Orthopaedic Research Laboratories, Room 2-41, Level 2, South Wing, Edmund Blacket Building, Department of Surgery, Prince of Wales Hospital, University of New South Wales, 2031, Sydney, Australia.
authors.forename: M
authors.initials: M
authors.lastname: Svehla
authors.forename: P
authors.initials: P
authors.lastname: Morberg
authors.forename: B
authors.initials: B
authors.lastname: Zicat
authors.forename: W
authors.initials: W
authors.lastname: Bruce
authors.forename: D
authors.initials: D
authors.lastname: Sonnabend
authors.forename: W R
authors.initials: WR
authors.lastname: Walsh
mesh_terms: D000497:Alloys; D000818:Animals; D001672:Biocompatible Materials; D017886:Durapatite; D020007:Implants, Experimental; D008297:Male; D008855:Microscopy, Electron, Scanning; D016062:Porosity; D012756:Sheep; D013314:Stress, Mechanical; D013499:Surface Properties; D013997:Time Factors; D014025:Titanium
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium