title: Proof of efficacy of Kamillosan(R) cream in atopic eczema.
abstract: Kamillosan(R) cream contains chamomile extract as active principle manufactured from the chamomile sort Manzana which is rich in active principles and has been proved not to exhibit a chamomile-related allergen potential. For this reason Kamillosan(R) cream is suited for local therapy of atopic eczema. In a partially double-blind, randomized study carried out as a half-side comparison, Kamillosan(R) cream was tested vs. 0.5% hydrocortisone cream and the vehicle cream as placebo in patients suffering from medium-degree atopic eczema. After a 2-week treatment Kamillosan(R) cream showed a mild superiority towards 0.5% hydrocortisone and a marginal difference as compared to placebo.
authors.affiliation: ASTA Medica AG, Weismüllerstr. 45, D-60314 Frankfurt am Main, Germany. Dr_Jeannette.Simon@astamedica.de
authors.forename: R
authors.initials: R
authors.lastname: Patzelt-Wenczler
authors.forename: E
authors.initials: E
authors.lastname: Ponce-Pöschl
mesh_terms: D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D016718:Arachidonic Acid / Q000378:metabolism; D001132:Arm; D020843:Chamomile / Q000627:therapeutic use; D003876:Dermatitis, Atopic / Q000188:drug therapy*; D004338:Drug Combinations; D004890:Erythema / Q000188:drug therapy; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage; D008875:Middle Aged; D009822:Oils, Volatile / Q000008:administration & dosage*; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage*; D010946:Plants, Medicinal; D011537:Pruritus / Q000188:drug therapy; D012717:Sesquiterpenes / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D004338:Drug Combinations; D009822:Oils, Volatile; D010936:Plant Extracts; D012717:Sesquiterpenes; C056251:Kamillosan; D016718:Arachidonic Acid; D006854:Hydrocortisone