title: KID syndrome associated with features of ichthyosis hystrix.
abstract: Keratitis-ichthyosis-deafness (KID) syndrome is a congenital ectodermal disorder causing erythrokeratoderma, vascularizing keratitis, and neurosensory deafness. Ichthyosis hystrix is a rare cutaneous disease characterized by well-demarcated, spiky, verrucous, linear plaques that is believed to be a clinical and pathologic chimera of two autosomal dominant diseases: epidermal nevus and epidermolytic hyperkeratosis. We present a patient with the classic triad of KID syndrome with clinical and histologic features of ichthyosis hystrix. This case demonstrates that KID syndrome comprises a spectrum of ectodermal disorders which may include diseases such as hystrix ichthyosis and deafness (HID) syndrome.
authors.affiliation: Department of Dermatology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA. hnousari@welchlink.welch.jhu.edu
authors.forename: H C
authors.initials: HC
authors.lastname: Nousari
authors.forename: A
authors.initials: A
authors.lastname: Kimyai-Asadi
authors.forename: J L
authors.initials: JL
authors.lastname: Pinto
mesh_terms: D001118:Argentina; D001707:Biopsy, Needle; D002648:Child; D003638:Deafness; D006801:Humans; D016112:Ichthyosis Vulgaris / Q000175:diagnosis* / Q000473:pathology; D007634:Keratitis / Q000175:diagnosis*; D008297:Male; D011379:Prognosis; D013577:Syndrome