Prevalence of hepatitis B and C in the sera of patients with HIV infection in São Paulo, Brazil.
The objective of this study was to evaluate the prevalence of hepatitis B and C viruses in a group of HIV infected patients, followed at a single institution since 1996. 1,693 HIV positive patients (1,162 male, 531 female) were tested for HBV infection. Virological markers for HBV included HBsAg and total anti-HBc by ELISA. 1,457 patients (1,009 male, 448 female) were tested for HCV infection. Detection of HCV antibodies was carried out by ELISA. A sample of HCV antibody positive patients was tested for HCV by PCR to confirm infection. Of 1,693 patients tested for HBV, 654 (38.6%) and 96 (5.7%) were anti-HBc and HBsAg positive, respectively. Of 1, 457 patients tested for HCV, 258 (17.7%) were anti-HCV positive. 82 of these patients were also tested by PCR and 81 were positive (98%). Of 1,411 patients tested for HBV and HCV 26 (1.8%) were positive for both viruses.
Mendes-Corrêa
M C
MC
AIDS Outpatient Clinic, Hospital das Clínicas, Infectious Diseases Department, School of Medicine, University of São Paulo, São Paulo, SP, Brazil. cassiamc@uol.com.br
Barone
A A
AA
Cavalheiro
N d
Nd
Tengan
F M
FM
Guastini
C
C
D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000821:virology*; D016174:Hepacivirus / Q000276:immunology / Q000302:isolation & purification*; D006510:Hepatitis B Antibodies / Q000097:blood*; D006515:Hepatitis B virus / Q000276:immunology / Q000302:isolation & purification*; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D015995:Prevalence
D015415:Biomarkers; D006510:Hepatitis B Antibodies; D018937:Hepatitis C Antibodies