title: Human toxocarosis. Its seroprevalence in the city of La Plata.
abstract: Toxocara canis is very common in dogs throughout the world. It is the primary cause of visceral larva migrans (VLM) in humans. Soil contaminated with T. canis embryonated eggs is the main source of infection of man. Our objective was to describe Toxocara seroprevalence in humans in the city of La Plata associated with some determinants such asage, presence or absence of clinical manifestations and risk factors. Blood samples were collected at random from 156 patients of different sex and age, with and without clinical symptoms compatible with the disease. The diagnostic technique ELISA test was performed with the Bordier Affinity Products Commercial Kit, using excretory-secretory Toxocara antigen with a sensitivity higher than 90%. The values were positive in 39% of the studied population. In the analysis according to age, the younger group presented significant differences with respect to the older one (Chi-square p<0.05). Positive patients presented clinical symptoms compatible with the disease (84%), and 41% presented some risk factor. The level of positivity obtained indicates a certain risk of being infects mainly in patients younger than 15 years old. The authors agree that an early identification and treatment of VLM may save a life.
authors.affiliation: Laboratorio de Parasitosis Humanas y Zoonosis Parasitarias, Facultad de Ciencias Veterinarias, UNLP, Buenos Aires, Argentina. nildarad@fcv.med.vet.unlp.edu.ar
authors.forename: N E
authors.initials: NE
authors.lastname: Radman
authors.forename: S M
authors.initials: SM
authors.lastname: Archelli
authors.forename: R D
authors.initials: RD
authors.lastname: Fonrouge
authors.forename: M
authors.initials: M
authors.lastname: del V Guardis
authors.forename: O R
authors.initials: OR
authors.lastname: Linzitto
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000818:Animals; D001118:Argentina / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D017166:Toxocara canis / Q000276:immunology / Q000302:isolation & purification; D014120:Toxocariasis / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*