Absence of S100A4 (mts1) gene mutations in various canine and feline tumours. Detection of a polymorphism in feline S100A4 (mts1).
Ninety canine and 101 feline tumours of various types were investigated for gene mutations in the coding regions of the metastasis-associated gene S100A4 (mts1). No gene mutations were present in the analysed genomic area. A widespread histidine/tyrosine polymorphism was detected in codon 17 of S100A4.
Mayr
B
B
Institute for Animal Breeding and Genetics, Veterinary University Vienna, Austria.
Brem
G
G
Reifinger
M
M
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002371:Cat Diseases / Q000235:genetics*; D002415:Cats; D019941:Cyclin-Dependent Kinase Inhibitor p16 / Q000737:chemistry / Q000235:genetics*; D004273:DNA, Neoplasm / Q000737:chemistry / Q000302:isolation & purification; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D004587:Electrophoresis, Agar Gel / Q000662:veterinary; D008969:Molecular Sequence Data; D009369:Neoplasms / Q000235:genetics / Q000662:veterinary*; D016133:Polymerase Chain Reaction / Q000662:veterinary; D011110:Polymorphism, Genetic / Q000235:genetics; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid
D019941:Cyclin-Dependent Kinase Inhibitor p16; D004273:DNA, Neoplasm