title: Sites of cleavage by restriction enzymes in viral DNAs: comparison of observed and expected frequencies.
abstract: Observed frequencies of restriction enzyme cleavage in viral DNAs are compared to those expected from the cleavage site sequence and the known size and nearest neighbour frequencies of the DNAs. It is found that a number of significant deviations from expectation occur, and possible explanations are put forward.
authors.forename: R A
authors.initials: RA
authors.lastname: Elton
mesh_terms: D010584:Bacteriophage phi X 174 / Q000737:chemistry; D001435:Bacteriophages / Q000737:chemistry; D001482:Base Composition; D001483:Base Sequence; D004262:DNA Restriction Enzymes / Q000378:metabolism*; D004279:DNA, Viral / Q000378:metabolism*; D008954:Models, Biological; D011336:Probability; D011897:Random Allocation; D013379:Substrate Specificity; D014780:Viruses / Q000737:chemistry
chemical_list: D004279:DNA, Viral; D004262:DNA Restriction Enzymes