A highly efficient synthesis of the hemibrevetoxin B ring system.
[reaction: see text] This Letter describes the synthesis of the hemibrevetoxin B tetracyclic ring system in 14 linear transformations from the Danishefsky-Kitahara diene.
Rainier
J D
JD
Department of Chemistry, The University of Arizona, Tucson 85721, USA. rainier@u.arizona.edu
Allwein
S P
SP
Cox
J M
JM
D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D008387:Marine Toxins / Q000138:chemical synthesis* / Q000737:chemistry*; D008722:Methods
D006576:Heterocyclic Compounds, 4 or More Rings; D008387:Marine Toxins; C409729:hemibrevetoxin B