[Drug-resistant bacteria of current topics and their resistance mechanisms--VRE].
VRE isolates have only been detected in eight patients from four hospitals in Japan since 1996(reports of the Ministry of Health and Welfare, Japan). In Japan, it has been shown that VRE are high frequently isolated from chickens imported from Thailand and France where avoparcin has been used in animal feed. Two types of acquired glycopeptide resistance have been reported in clinical isolates of VRE. The VanA type strain is defined as having a high-level resistance to vancomycin and teicoplanin. The vanA resistance genes are induced by both vancomycin and teicoplanin. VanB type strains are characterized as having various levels of vancomycin resistance and are susceptible to teicoplanin. The vanB resistance genes are induced by vancomycin only.
Ike
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Department of Mycrobiolog, Gumma University Faculty of Medicine.
D016983:Enterococcus / Q000187:drug effects* / Q000235:genetics; D020713:Vancomycin Resistance