A cytokeratin profile of canine epithelial skin tumours.
The reactions of a number of epithelial skin tumours in dogs to a panel of monoclonal antibodies against different human cytokeratins (CKs) were examined immunohistochemically, the purpose being to detect a specific CK profile. CK 6 was present in all epithelial skin tumours with the exception of pilomatrixoma. CK 14 was found in basal cell-derived neoplasias and in sebaceous and perianal gland tumours. CK 10/11 was restricted to spinous cell-derived tumours and CK 8/18 was limited to sweat gland tumours.
Walter
J
J
Institut für Veterinär-Pathologie der Freie Universität Berlin, Strasse 518 Nr. 15, Berlin, D-14163, Germany.
D000818:Animals; D002280:Basal Cell Carcinoma / Q000737:chemistry / Q000662:veterinary; D002294:Carcinoma, Squamous Cell / Q000737:chemistry / Q000662:veterinary; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis*; D012867:Skin / Q000737:chemistry; D012878:Skin Neoplasms / Q000737:chemistry / Q000662:veterinary*
D007633:Keratins