Synthesis of glycophostones: cyclic phosphonate analogues of biologically relevant sugars
Analogues of L-fucose, N-acetyl-D-glucosamine, N-acetyl-D-mannosamine, and N-acetyl neuraminic acid in which the anomeric carbon atom was replaced by a phosphonyl group (phostones or cyclic phosphonates) were synthesized by stereocontrolled methods relying on the Abramov reaction.
Hanessian
S
Department of Chemistry, Universite de Montreal, Quebec, Canada.
Rogel
O