title: [Oligo(2'-O-tetrahydropyranylribonucleotides): hybridization properties and nuclease resistance].
abstract: Oligo(2'-tetrahydropyranylribonucleotides) and their analogues containing a 3'-3'-internucleotide bond at the 3'-terminus are nuclease-resistant and possess rather high affinity toward RNA, the main target in the antisense approach.
authors.affiliation: Novosibirsk Institute of Bioorganic Chemistry, Siberian Division, Russian Academy of Sciences, Russia.
authors.forename: M A
authors.initials: MA
authors.lastname: Kuznetsova
authors.forename: D V
authors.initials: DV
authors.lastname: Pyshnyĭ
authors.forename: M N
authors.initials: MN
authors.lastname: Repkova
authors.forename: A G
authors.initials: AG
authors.lastname: Ven'iaminova
mesh_terms: D000818:Animals; D020320:Oligoribonucleotides, Antisense / Q000737:chemistry*; D011714:Pyrans / Q000737:chemistry*; D012260:Ribonucleases / Q000737:chemistry
chemical_list: D020320:Oligoribonucleotides, Antisense; D011714:Pyrans; D012260:Ribonucleases