[Detection methods for drug-resistant bacteria in routine examination--ESBL].
Extended-spectrum beta-lactamases(ESBLs) confer resistance to cefotaxime, ceftazidime, aztreonam, extended-spectrum penicillins, and structurally related beta-lactams in clinical isolates of K. pneumoniae and E. coli. Some ESBLs, however, show a lower level of resistance and these isolates may not reach NCCLS breakpoints for resistance. Optimal methods for confirmation of ESBL-producing isolates are described.
Okamoto
R
R
Department of Microbiology, Kitasato University School of Medicine.
D004926:Escherichia coli / Q000201:enzymology*; D006801:Humans; D007711:Klebsiella pneumoniae / Q000201:enzymology*; D008826:Microbial Sensitivity Tests; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000378:metabolism*
D001618:beta-Lactamases