title: Acute effects of bushfires on peak expiratory flow rates in children with wheeze: a time series analysis.
abstract: OBJECTIVE
  To determine the effects of the January 1994 Sydney bushfire on evening peak expiratory flow rates (PEFR) in children with wheeze.
  
  
  METHODS
  Children with a history of wheeze were enrolled in the longitudinal study and completed a daily asthma diary. We obtained daily air pollution, meteorological, pollen and alternaria data. We then used generalised estimating equation techniques to determine associations between the bushfire period and particulate matter less than 10 microns (PM10) and PEFR.
  
  
  RESULTS
  The maximum daily PM10 level peaked at 210 ug/m3, which was nearly seven times the usual PM10 level for the rest of January and February 1994. There was no significant association between mean PM10 and PEFR (beta-coefficient = -0.009, p = 0.86). Children without bronchial hyper-reactivity had a significant negative association between PEFR and PM10 (beta-coefficient = -0.1029, p = 0.03). The bushfire period was not significant in any of the models.
  
  
  CONCLUSIONS
  We did not find an association between the bushfire period or PM10 and evening PEFR, although in a subgroup of children without bronchial hyper-reactivity, a significant negative association was present between PM10 and evening PEFR.
  
  
  CONCLUSIONS
  We conclude that the high levels of particulate pollution caused by the Sydney bushfires did not lead to any clinically significant reductions in PEFR in symptomatic children. Our results have implications for community risk communication during future bushfires.
authors.affiliation: Epidemiology Unit, Liverpool Hospital, New South Wales. b.jalaludin@unsw.edu.au
authors.forename: B
authors.initials: B
authors.lastname: Jalaludin
authors.forename: M
authors.initials: M
authors.lastname: Smith
authors.forename: B
authors.initials: B
authors.lastname: O'Toole
authors.forename: S
authors.initials: S
authors.lastname: Leeder
mesh_terms: D000397:Air Pollution / Q000009:adverse effects* / Q000032:analysis; D016535:Bronchial Hyperreactivity / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D002648:Child; D005260:Female; D005390:Fires / Q000706:statistics & numerical data; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009517:New South Wales; D010366:Peak Expiratory Flow Rate; D012135:Respiratory Sounds / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D012307:Risk Factors; D012621:Seasons; D012906:Smoke / Q000009:adverse effects* / Q000032:analysis; D013997:Time Factors; D014504:Urban Health / Q000706:statistics & numerical data
chemical_list: D012906:Smoke