Monoclonal antibody differentiation of Mycoplasma mycoides subsp. mycoides small-colony strains causing contagious bovine pleuropneumonia from less important large-colony strains.
Monoclonal antibody (MAb) PK-2 inhibited the in vitro growth of nine Mycoplasma mycoides subsp. mycoides small-colony strains. In contrast to the results with polyclonal antisera, growth inhibition by MAb PK-2 was specific for M. mycoides subsp. mycoides small-colony strains and constituted a reliable means of distinguishing them from other mycoplasmas.
Rurangirwa
F R
FR
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington 99164-7040, USA. ruvuna@vetmed.wsu.edu
Shompole
P S
PS
Wambugu
A N
AN
McGuire
T C
TC
D000818:Animals; D000907:Antibodies, Bacterial / Q000494:pharmacology; D000911:Antibodies, Monoclonal / Q000494:pharmacology; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis* / Q000276:immunology; D003429:Cross Reactions; D009176:Mycoplasma mycoides / Q000254:growth & development / Q000276:immunology* / Q000302:isolation & purification*; D011002:Pleuropneumonia, Contagious / Q000175:diagnosis* / Q000276:immunology; D013045:Species Specificity
D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal