Quinolone resistance in enterotoxigenic Escherichia coli causing diarrhea in travelers to India in comparison with other geographical areas.
Enterotoxigenic Escherichia coli isolates were identified as a cause of traveler's diarrhea in 82 of 520 (16%) patients and tested for resistance to seven antimicrobial agents. Thirty patients (36%) needed antimicrobial therapy: 17 (56%) for persistence of symptoms and 13 (44%) for severity of symptoms. Ampicillin, tetracycline, and trimethoprim-sulfamethoxazole resistance was high. Chloramphenicol showed moderate activity, and amoxicillin plus clavulanic acid, nalidixic acid, and ciprofloxacin showed very good activity. Five nalidixic acid-resistant strains were isolated, four from patients visiting India.
Vila
J
J
Department of Microbiology, IDIBAPS (Institut d'Investigacions Biomèdiques August Pí i Sunyer), Hospital Clínic, School of Medicine, University of Barcelona, Barcelona, Spain. vila@medicina.ub.es
Vargas
M
M
Ruiz
J
J
Corachan
M
M
Jimenez De Anta
M T
MT
Gascon
J
J
D003967:Diarrhea / Q000453:epidemiology / Q000209:etiology*; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects*; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000209:etiology*; D007194:India; D015363:Quinolones / Q000494:pharmacology*
D015363:Quinolones