title: Pharyngeal dysphagia in postesophagectomy patients: correlation with deglutitive biomechanics.
abstract: BACKGROUND
  Because of the transient nature of pharyngeal phase dysphagia, posttranshiatal esophagectomy patients provide a model for studying the correlation of dysphagic symptoms and aspiration with deglutitive biomechanics.
  
  
  METHODS
  We studied 8 transhiatal esophagectomy patients (age range, 51 to 78 years) and 8 normal age-matched controls in upright position using lateral and anteroposterior (AP) projection videofluoroscopy during three 5 mL barium swallows.
  
  
  RESULTS
  The maximum upper esophageal sphincter (UES) AP diameter and maximum anterior excursion of the hyoid bone in patients with transhiatal esophagectomy who experienced aspiration (6.2+/-0.6 and 9.0+/-2.0 mm, respectively) were significantly smaller than those of age-matched normal controls (9.4+/-0.7 and 17.0+/-1.0 mm, respectively). Resolution of aspiration was associated with a significant increase in AP diameter of the UES as well as anterior and superior excursion of the hyoid bone (p<0.05).
  
  
  CONCLUSIONS
  Dysphagic symptoms and aspiration in posttranshiatal esophagectomy patients are associated with significant abnormalities of deglutitive biomechanics. Improvement in deglutitive biomechanics is associated with resolution of dysphagic symptoms as well as postdeglutitive aspiration in these patients.
authors.affiliation: Dysphagia Institute, Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Zablocki Veterans Affairs Medical Center, Milwaukee, USA.
authors.forename: C S
authors.initials: CS
authors.lastname: Easterling
authors.forename: M
authors.initials: M
authors.lastname: Bousamra
authors.forename: I M
authors.initials: IM
authors.lastname: Lang
authors.forename: M K
authors.initials: MK
authors.lastname: Kern
authors.forename: T
authors.initials: T
authors.lastname: Nitschke
authors.forename: E
authors.initials: E
authors.lastname: Bardan
authors.forename: R
authors.initials: R
authors.lastname: Shaker
mesh_terms: D000368:Aged; D001696:Biomechanical Phenomena; D003679:Deglutition / Q000502:physiology*; D003680:Deglutition Disorders / Q000209:etiology*; D016629:Esophagectomy; D006801:Humans; D008875:Middle Aged; D010614:Pharynx / Q000503:physiopathology*; D014741:Video Recording