title: Non-enveloped viruses transmitted by blood and blood products.
abstract: Since the advent of solvent detergent (S-D) treatment for inactivation of enveloped viruses, there has been no transmission of human immunodeficiency virus, hepatitis B virus, or hepatitis C virus by treated blood products. However, shortly after the introduction of S-D treatment, transmission of hepatitis A with S-D treated factor concentrates was reported in Germany, Italy, Ireland, the United States and South Africa, and this raised awareness of the potential for blood transmission of non-enveloped viruses in general. This report summarizes the physical and epidemiological features of three non-enveloped viruses, hepatitis A virus, parvovirus B19, and the recently identified TT virus, and their transmission by blood and blood products.
authors.affiliation: Hepatitis Branch A-33, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
authors.forename: B H
authors.initials: BH
authors.lastname: Robertson
authors.forename: D D
authors.initials: DD
authors.lastname: Erdman
mesh_terms: D001688:Biological Products; D018136:Circoviridae; D018173:Circoviridae Infections / Q000097:blood / Q000453:epidemiology / Q000635:transmission* / Q000821:virology; D006506:Hepatitis A / Q000097:blood / Q000453:epidemiology / Q000635:transmission* / Q000821:virology; D006507:Hepatovirus; D006801:Humans; D010322:Parvoviridae Infections / Q000097:blood / Q000453:epidemiology / Q000635:transmission* / Q000821:virology; D016732:Parvovirus B19, Human
chemical_list: D001688:Biological Products