title: Beating heart surgery in octogenarians: perioperative outcome and comparison with younger age groups.
abstract: BACKGROUND
  Octogenarians have higher morbidity and mortality rates (9% to 16%) after coronary artery bypass grafting with cardiopulmonary bypass, compared with younger patients.
  
  
  METHODS
  We compared the perioperative outcome and hospital stay after coronary artery bypass grafting without cardiopulmonary bypass (off-pump) from January 1987 to May 1999, among patients older than 80 years (n = 71), patients between 70 and 79 years (n = 228), and patients whose age ranged from 60 to 69 years (n = 296). In comparison with younger patients, more octogenarians were female (51% versus 39% in patients aged 70 to 79 years and 35% in those aged 60 to 69 years, p = 0.04), they had previous myocardial infarction more frequently (48% versus 47% versus 34%, respectively, p = 0.008), and were operated on urgently (69% versus 56% versus 52%, respectively, p = 0.04).
  
  
  RESULTS
  Postoperative complications that were significantly higher in octogenarians compared with younger groups included pneumonia (6% in octogenarians versus 2% in patients aged 70 to 79 years and 0% in patients aged 60 to 69 years, p = 0.001) and atrial fibrillation (47% versus 32% versus 21%, respectively, p<0.001). By multivariate logistic regression analysis, age over 80 years was an independent predictor of prolonged hospital stay (odds ratio = 2.7, 95% confidence interval, 1.4 to 5, p<0.001). The in-hospital mortality rate was higher in octogenarians (6% versus 3% for 70 to 79 year-olds and 0.3% for 60 to 69 year-olds, p = 0.006).
  
  
  CONCLUSIONS
  When appropriately applied in patients older than 80 years, off-pump coronary artery bypass grafting can be done with acceptable postoperative morbidity, mortality, and hospital stay.
authors.affiliation: Department of Surgery, Washington Hospital Center, Washington, DC 20010, USA.
authors.forename: S C
authors.initials: SC
authors.lastname: Stamou
authors.forename: G
authors.initials: G
authors.lastname: Dangas
authors.forename: M K
authors.initials: MK
authors.lastname: Dullum
authors.forename: A J
authors.initials: AJ
authors.lastname: Pfister
authors.forename: S W
authors.initials: SW
authors.lastname: Boyce
authors.forename: A S
authors.initials: AS
authors.lastname: Bafi
authors.forename: J M
authors.initials: JM
authors.lastname: Garcia
authors.forename: P J
authors.initials: PJ
authors.lastname: Corso
mesh_terms: D000367:Age Factors; D000368:Aged; D001026:Coronary Artery Bypass / Q000401:mortality*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007902:Length of Stay; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D009017:Morbidity; D011183:Postoperative Complications; D012189:Retrospective Studies; D016019:Survival Analysis