[Time course of serum nuclease activity in mice infected with Plasmodium berghei].
The present paper shows that murine serum nuclease activity increases following P.berghei infection. DNA activity begins increasing just 48 hours after infection. Following 78 hours, it achieves the maximum, by exceeding the baseline level by 6 times. Then DNA activity starts decreasing and following 94 hours after infection it is just thrice higher than the baseline. Serum RNA activity shows only 30% increases 72 hours after infection and returns to the baseline following 94 hours. Microscopic monitoring indicates that only single malaria causative agents appear in the red blood cells in this period. The peak increases in nuclease activities after P.berghei infection are assumed to be associated with the induction of serum infection.
Kovalenko
G A
GA
Gal'vita
A V
AV
D000209:Acute-Phase Proteins / Q000096:biosynthesis; D000818:Animals; D003851:Deoxyribonucleases / Q000096:biosynthesis* / Q000097:blood*; D004790:Enzyme Induction; D007700:Kinetics; D008288:Malaria / Q000097:blood; D051379:Mice; D008815:Mice, Inbred Strains; D010962:Plasmodium berghei; D012260:Ribonucleases / Q000096:biosynthesis* / Q000097:blood*; D013997:Time Factors
D000209:Acute-Phase Proteins; D003851:Deoxyribonucleases; D012260:Ribonucleases