title: A new selective synthesis of the Ile-allo-Thr-Gly tripeptide fragment of lysobactin.
abstract: [formula: see text] trans-Aziridine-2-carboxylic acid derivatives are useful intermediates for the synthesis of threonine or allo-threonine through ring expansion and SN2 displacement, respectively. We describe here the preparation of the Ile-allo-Thr-Gly 11 fragment of Lysobactin via the aziridine 9 intermediate.
authors.affiliation: Dipartimento di Chimica G. Ciamician, Università di Bologna, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Armaroli
authors.forename: G
authors.initials: G
authors.lastname: Cardillo
authors.forename: L
authors.initials: L
authors.lastname: Gentilucci
authors.forename: M
authors.initials: M
authors.lastname: Gianotti
authors.forename: A
authors.initials: A
authors.lastname: Tolomelli
mesh_terms: D047630:Depsipeptides; D009682:Magnetic Resonance Spectroscopy; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000737:chemistry; D010446:Peptide Fragments / Q000138:chemical synthesis*; D011487:Protein Conformation
chemical_list: D047630:Depsipeptides; D009842:Oligopeptides; D010446:Peptide Fragments; C056790:katanosin B