Haploidentical transplantation.
When allogeneic transplant is indicated and a MSD is not available, most centers first seek an unrelated donor. However, one must avoid undue delays when a donor is not available and family members should be typed to identify the preferred donor amongst the family. Since a family donor can provide access to transplant for almost every patient, a greater effort should be encouraged to improve and expand haploidentical transplantation. The advantages, outlined in Table 1, suggest compelling reason to perfect the use of haploidentical related donors.
Henslee-Downey
P J
PJ
South Carolina Cancer Center, University of South Carolina, Columbia, USA.
D005190:Family; D006239:Haplotypes; D018380:Hematopoietic Stem Cell Transplantation; D006650:Histocompatibility Testing; D006801:Humans; D019520:Living Donors; D014184:Transplantation, Homologous / Q000276:immunology*