title: [Nebivolol: a beta blocker with vasodilator properties].
abstract: Nebivolol is a new cardioselective beta-blocking agent possessing vasodilatory properties involving the endothelium. This compound is a dl-racemic mixture. The d-enantiomer is responsible for the beta-blocking properties whereas the l-enantiomer induces a vasodilation via a nitric oxide (NO) mechanism. Nebivolol is an unique agent that appears promising for the management of patients with hypertension, coronary heart disease or congestive heart failure.
authors.affiliation: Division de Physiopathologie clinique et de pédagogie médicale, CHUV, Lausanne.
authors.forename: B
authors.initials: B
authors.lastname: Waeber
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D001578:Benzopyrans / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004730:Endothelium, Vascular / Q000187:drug effects; D004983:Ethanolamines / Q000627:therapeutic use*; D006801:Humans; D000068577:Nebivolol; D014665:Vasodilator Agents / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000319:Adrenergic beta-Antagonists; D001578:Benzopyrans; D004983:Ethanolamines; D014665:Vasodilator Agents; D000068577:Nebivolol