title: Metabolic transformation of the brassinosteroid 24-epi-castasterone by the cockroach Periplaneta americana.
abstract: After feeding of 24-epi-castasterone to the cockroach Periplaneta americana an organ-specific epimerization of the brassinosteroid to 2,24-diepi-castasterone could be detected in female insects. The metabolite being observed only in the ovaries and not in the testes of the insect was identified by GC/MS in comparison with a synthesized authentic sample. Contrary, 24-epi-brassinolide is not metabolized in the sexual organs of Periplaneta americana. This is the first evidence of a metabolic transformation of a brassinosteroid in insects.
authors.affiliation: Leibniz-Institut für Pflanzenbiochemie, Abteilung Naturstoffchemie, Halle/S., Germany. jschmidt@ipb.uni-halle.de
authors.forename: J
authors.initials: J
authors.lastname: Schmidt
authors.forename: K
authors.initials: K
authors.lastname: Richter
authors.forename: B
authors.initials: B
authors.lastname: Voigt
authors.forename: G
authors.initials: G
authors.lastname: Adam
mesh_terms: D000818:Animals; D001711:Biotransformation; D002777:Cholestanols / Q000493:pharmacokinetics*; D003058:Cockroaches / Q000378:metabolism*; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D008297:Male
chemical_list: D002777:Cholestanols; C083545:castasterone