Melleolides K, L and M, new melleolides from Armillariella mellea.
Three new sesquiterpenoid aromatic esters designated melleolides K (1), L (2) and M (3) were isolated from the cultured mycelia of Armillariella mellea (Vahl. ex Fr.) Karst. Structures of these compounds were determined on the basis of various NMR spectral data, chemical transformations and X-ray analysis. Compounds 1, 2 and 3 showed antimicrobial activities.
Momose
I
I
Institute of Microbial Chemistry, Tokyo, Japan.
Sekizawa
R
R
Hosokawa
N
N
Iinuma
H
H
Matsui
S
S
Nakamura
H
H
Naganawa
H
H
Hamada
M
M
Takeuchi
T
T
D000363:Agaricales / Q000737:chemistry*; D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D018360:Crystallography, X-Ray; D005658:Fungi / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D007928:Lethal Dose 50; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D018675:Toxicity Tests
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D012717:Sesquiterpenes; C408304:melleolide K; C408306:melleolide L; C408305:melleolide M