title: [Significance of exercise-induced ST segment depression in patients with myocardial infarction involving the left circumflex artery: evaluation by exercise thallium-201 myocardial single photon emission computed tomography].
abstract: The significance of exercise-induced ST segment depression in patients with left circumflex artery involvement was investigated by comparing exercise electrocardiography with exercise thallium-201 single photon emission computed tomography(Tl-SPECT) and the wall motion estimated by left ventriculography. Tl-SPECT and exercise electrocardiography were simultaneously performed in 51 patients with left circumflex artery involvement(angina pectoris 30, myocardial infarction 21). In patients with myocardial infarction, exercise-induced ST depression was frequently found in the V2, V3 and V4 leads. In patients with angina pectoris, ST depression was frequently found in the II, III, aVF, V5 and V6 leads. There was no obvious difference in the leads of ST depression in patients with myocardial infarction with ischemia and without ischemia on Tl-SPECT images. In patients with myocardial infarction, the lateral wall motion of the infarcted area evaluated by left ventriculography was more significantly impaired in the patients with ST depression than without ST depression(p < 0.01). Exercise-induced ST depression in the precordial leads possibly reflects wall motion abnormality rather than ischemia in the lateral infarcted myocardium.
authors.affiliation: Division of Cardiology, Gunma Prefectural Cardiovascular Center.
authors.forename: N
authors.initials: N
authors.lastname: Koitabashi
authors.forename: T
authors.initials: T
authors.lastname: Toyama
authors.forename: H
authors.initials: H
authors.lastname: Hoshizaki
authors.forename: N
authors.initials: N
authors.lastname: Isobe
authors.forename: M
authors.initials: M
authors.lastname: Suguta
authors.forename: M
authors.initials: M
authors.lastname: Nakatsugawa
authors.forename: T
authors.initials: T
authors.lastname: Kawakami
authors.forename: Y
authors.initials: Y
authors.lastname: Horie
authors.forename: S
authors.initials: S
authors.lastname: Hiroi
authors.forename: H
authors.initials: H
authors.lastname: Tada
authors.forename: H
authors.initials: H
authors.lastname: Adachi
authors.forename: S
authors.initials: S
authors.lastname: Naito
authors.forename: A
authors.initials: A
authors.lastname: Nogami
authors.forename: S
authors.initials: S
authors.lastname: Ohshima
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000503:physiopathology; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology*; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D013794:Thallium Radioisotopes