[Annular erythema in Sjögren syndrome. A variant of cutaneous lupus erythematosus?].
Annular erythema has been recognised as a cutaneous manifestation of Sjögren's syndrome in the Asian literature and has been assumed to represent a distinct clinical entity. Since there are common pathophysiologic mechanisms, mainly the presence of anti-Ro/SSA or anti-La/SSB antibodies, it is difficult to separate the annular erythema from subacute cutaneous lupus erythematosus. Histological examination may reveal dermal mucin deposition resembling lupus erythematosus tumidus. We present a Chinese patient with widespread annular erythema, keratoconjunctivitis sicca, and anti-Ro/SSA antibodies. Clinical, histopathological, and immunogenetic findings are discussed reviewing the current literature, and the differences between annular erythema associated with Sjögren's syndrome and cutaneous lupus erythematosus are emphasized.
Kuhn
A
A
Hautklinik der Heinrich-Heine-Universität Düsseldorf.
Richter-Hintz
D
D
Schuppe
H C
HC
Ruzicka
T
T
Lehmann
P
P
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D002681:China / Q000208:ethnology; D004890:Erythema / Q000175:diagnosis* / Q000473:pathology; D005858:Germany; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D012859:Sjogren's Syndrome / Q000175:diagnosis* / Q000473:pathology; D012867:Skin / Q000473:pathology
D000974:Antibodies, Antinuclear; C035356:SS-A antibodies