title: Growth of adolescents who were born at extremely low birth weight without major disability.
abstract: OBJECTIVE
  To compare growth between adolescents who were born at extremely low birth weight (ELBW, </=1000 g) and adolescents who were born at normal birth weight (NBW, >/=2500 g).
  
  
  METHODS
  Cross-sectional design. Fifty-three ELBW and 53 NBW adolescents without a major neurodevelopmental disability were matched by sex, race, age, and socioeconomic status. Anthropometrics (z scores), bone age, body composition (Lunar DPX-L densitometry), and sexual maturity were assessed. ELBW adolescents were classified as being born small for gestational age (SGA) or not (NSGA).
  
  
  RESULTS
  Subjects were 58.5% female, 43.4% black, and 56.6% white. The mean birth weight for ELBW subjects was 849 g and 3355 g for NBW subjects. The mean age was 14.85 years. On average, ELBW adolescents were 4.8 cm shorter and 9.1 kg lighter than NBW adolescents. ELBW adolescents had lower mean z scores for height (P <.0001), weight (P <.0001), and head circumference (P <.0001) than NBW adolescents. ELBW/SGA subjects had lower mean z scores for height (P <.0001) and weight (P =.001) than NBW subjects. Head circumference z scores were lower for the ELBW/SGA group than the ELBW/NSGA group or the NBW group (P =. 003). Sexual maturity and relative body composition were similar between groups. Bone age, measured in SD units, was more advanced in the ELBW group (0.86 vs. 0.42, P =.039).
  
  
  CONCLUSIONS
  ELBW adolescents who survive without a major neurodevelopmental disability attain lower growth measurements compared with NBW adolescents but have similar sexual maturation and relative body composition.
authors.affiliation: Division of General Pediatrics, the Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA.
authors.forename: M
authors.initials: M
authors.lastname: Peralta-Carcelen
authors.forename: D S
authors.initials: DS
authors.lastname: Jackson
authors.forename: M I
authors.initials: MI
authors.lastname: Goran
authors.forename: S A
authors.initials: SA
authors.lastname: Royal
authors.forename: M S
authors.initials: MS
authors.lastname: Mayo
authors.forename: K G
authors.initials: KG
authors.lastname: Nelson
mesh_terms: D000293:Adolescent; D001724:Birth Weight; D001823:Body Composition; D001824:Body Constitution; D003430:Cross-Sectional Studies; D005260:Female; D006128:Growth; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age / Q000254:growth & development; D019102:Infant, Very Low Birth Weight / Q000254:growth & development*; D008297:Male; D009420:Nervous System / Q000254:growth & development; D012741:Sexual Maturation; D012923:Social Class