[Clinical analysis of intracranial venous embolism during pregnancy and puerperium].
OBJECTIVE
To study the cause and clinical manifestation of intracranial venous embolim during pregnancy and puerperium, and its early diagnosis and treatment.


METHODS
18 cases of intracranial venous embolism confirmed by Computed Tomography (CT) were eligible for this retrospective study.


RESULTS
Of all the cases, 8 cases occurred before delivery and 10 post partum; 10 cases complicated by pregnancy induced hypertension and 8 cases postpartum hemorrhage. Headache occurred most frequently, followed by coma and seizure. Blood rheologic assay showed hypercoagulable states in 6 cases. For 11 cases treated with urokinase, 10 were cured, while in the remaining patients, 3 of 6 cured.


CONCLUSIONS
The results show that hypercoagulability states were related to intracranial venous embolism. Coma and seizure were the main characters. CT was an important diagnostic measure. Lowering intracranial pressure, anticoagulation, dethrombosis and timely ending pregnancy were the main treatment measures. The early use of urokinase may exert better effect.
Wang
S
S
Affiliated Hospital, Hebei Medical College for Continuing Enducation, Baoding.
Liang
Y
Y
Zhao
F
F
D000328:Adult; D005260:Female; D006801:Humans; D020766:Intracranial Embolism / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000209:etiology*; D011644:Puerperal Disorders / Q000175:diagnosis / Q000209:etiology*; D012189:Retrospective Studies; D019851:Thrombophilia / Q000150:complications*; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use
D014568:Urokinase-Type Plasminogen Activator