Association of venous thromboembolism and clozapine.
Data from the Swedish Adverse Reactions Advisory Committee suggest that use of clozapine is associated with venous thromboembolic complications. We summarise 12 cases of thromboembolism during clozapine treatment. In five cases the outcome was fatal.
Hägg
S
S
Spigset
O
O
Söderström
T G
TG
D000328:Adult; D016907:Adverse Drug Reaction Reporting Systems / Q000706:statistics & numerical data; D014150:Antipsychotic Agents / Q000009:adverse effects*; D003024:Clozapine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000139:chemically induced*; D013548:Sweden / Q000453:epidemiology; D020246:Venous Thrombosis / Q000139:chemically induced*
D014150:Antipsychotic Agents; D003024:Clozapine