title: Enantioselective photocyclization of amides to beta-lactam derivatives in inclusion crystals with an optically active host
abstract: Irradiation of inclusion crystals of 2-(N-acyl-N-alkylamino)cyclohex-2-enones and N,N-dimethylphenylglyoxylamide with chiral host molecules gave the optically active N-alkyl-1-azaspiro[3.5]-nonane-2,5-diones and 3-hydroxy-1-methyl-3-phenylazetidin-2-one, respectively. The crystal structure of the 1:1 inclusion complex of N,N-dimethylphenylglyoxylamide with (-)-trans-1,4-bis[3-(o-chlorophenyl)-3-hydroxy-3-phenylprop-1-ynyl]-2,3,5,6- tetrachloro-2,5-cyclohexadiene-1,4-diol was analyzed by X-ray diffraction.
authors.affiliation: Department of Chemistry, Faculty of Science, Okayama University of Science, Japan.
authors.initials: F
authors.lastname: Toda
authors.initials: H
authors.lastname: Miyamoto
authors.initials: M
authors.lastname: Inoue
authors.initials: S
authors.lastname: Yasaka
authors.initials: I
authors.lastname: Matijasic