title: Establishing guidelines for pharmacotherapy trials in bulimia nervosa and anorexia nervosa.
abstract: OBJECTIVE
  This paper addresses the lack of a standard protocol for pharmacotherapy trials for patients with bulimia nervosa (BN) and anorexia nervosa (AN).
  
  
  METHODS
  Twenty-two surveys were sent to established researchers in the field of eating disorders to elicit their opinions regarding medication trials, including baseline laboratory tests, the optimal length/frequency of medication management sessions, and the information that should or should not be included in these sessions.
  
  
  RESULTS
  Sixteen of 22 researchers completed and returned the survey. Their answers are the basis of the data presented.
  
  
  CONCLUSIONS
  We propose a battery of screening laboratory tests for both conditions. We suggest 30-45-min initial medication management sessions in both AN and BN trials with 15-min follow-ups to be held weekly for AN subjects, and weekly for 2 weeks, then biweekly for 2 weeks, then monthly, for BN subjects. We also recommend that published trials should include explicit details of medication management.
authors.affiliation: Neuropsychiatric Research Institute/University of North Dakota School of Medicine, Fargo, North Dakota 58107, USA. mitchell@medicine.nodak.edu
authors.forename: J E
authors.initials: JE
authors.lastname: Mitchell
authors.forename: B
authors.initials: B
authors.lastname: Tareen
authors.forename: W
authors.initials: W
authors.lastname: Sheehan
authors.forename: S
authors.initials: S
authors.lastname: Agras
authors.forename: T D
authors.initials: TD
authors.lastname: Brewerton
authors.forename: S
authors.initials: S
authors.lastname: Crow
authors.forename: M
authors.initials: M
authors.lastname: Devlin
authors.forename: E
authors.initials: E
authors.lastname: Eckert
authors.forename: K
authors.initials: K
authors.lastname: Halmi
authors.forename: D
authors.initials: D
authors.lastname: Herzog
authors.forename: M
authors.initials: M
authors.lastname: Marcus
authors.forename: P
authors.initials: P
authors.lastname: Powers
authors.forename: A
authors.initials: A
authors.lastname: Stunkard
authors.forename: B T
authors.initials: BT
authors.lastname: Walsh
mesh_terms: D000856:Anorexia Nervosa / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy*; D001291:Attitude of Health Personnel; D002032:Bulimia / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy*; D002985:Clinical Protocols / Q000592:standards; D016903:Drug Monitoring / Q000379:methods / Q000592:standards; D006801:Humans; D008403:Mass Screening / Q000379:methods / Q000592:standards; D010353:Patient Education as Topic / Q000379:methods / Q000592:standards; D010819:Physician's Role; D017410:Practice Guidelines as Topic / Q000592:standards*; D016032:Randomized Controlled Trials as Topic / Q000592:standards*; D012108:Research Personnel / Q000523:psychology; D011795:Surveys and Questionnaires