Five- to fifteen-year follow-up of fresh autologous pericardial valved conduits.
OBJECTIVE
Evaluate long-term results of autologous pericardial valved conduits in the pulmonary outflow.


METHODS
Between June 1983 and October 1993, 82 conduits were placed in the outflow of the venous ventricle. Patients who received homografts (n = 2 patients), heterografts (n = 3 patients), and valveless conduits (n = 19 patients) and those patients who died within 90 days after the operation were excluded. Fifty-four survivors of pulmonary outflow reconstruction with fresh autologous pericardial valved conduits were followed up from 5 to 15 years (mean, 7.47 +/- 2.8 years). Diagnosis include d -transposition of great arteries (n = 16 patients), L -transposition of great arteries (n = 14 patients), tetralogy of Fallot, pulmonary atresia with ventricular septal defect (n = 11 patients), truncus arteriosus (n = 10 patients), and double-outlet ventricle (n = 3 patients). Implantation age ranged from 0.25 to 24 years (mean, 5.2 +/- 4.2 years). Median conduit diameter was 16 mm. Two-dimensional echocardiographic Doppler evaluations were made yearly; 9 patients underwent cardiac catheterization. Reintervention for stenosis was indicated when the pressure gradient exceeded 50 mm Hg.


RESULTS
Three late deaths were unrelated to the conduit. Thirty-five autologous pericardial valved conduits increased in diameter (1-7 mm), remained unchanged in 15 patients, and reduced 1 to 2 mm in 4 patients. The median diameter was 18 mm at the last evaluation (P =.0001). Eight patients required conduit-related reoperation 3 to 8 years after the implantation. Two patients underwent balloon dilation of the autologous pericardial valved conduit. No conduit had to be replaced. Freedom from reintervention at 5 and 10 years was 92% and 76%, being 100% at 10 years for conduits larger than 16 mm at time of implantation.


CONCLUSIONS
Autologous pericardial valved conduits show excellent long-term results and compare favorably with other conduits.
Schlichter
A J
AJ
Children's Hospital "Ricardo Gutierrez" and Clinica Bazterrica, Buenos Aires, Argentina. schlichter@overnet.com.ar
Kreutzer
C
C
Mayorquim
R C
RC
Simon
J L
JL
Román
M I
MI
Vazquez
H
H
Kreutzer
E A
EA
Kreutzer
G O
GO
Jonas
S R
SR
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D015150:Echocardiography, Doppler; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D010496:Pericardium / Q000637:transplantation*; D011183:Postoperative Complications; D011664:Pulmonary Valve / Q000601:surgery*; D012086:Reoperation; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D015996:Survival Rate; D014182:Transplantation, Autologous; D016896:Treatment Outcome