title: Diastereoselective synthesis of non-proteinogenic alpha-amino acids.
abstract: The synthesis of enantiomerically pure azatyrosine, tribromophenylalanine and trichlorophenylalanine is described, using two methods, diastereoselective alkylation and (or) diastereoselective protonation of chiral enolates.
authors.affiliation: Laboratoire d'Aminoacides, Peptides et Protéines, Université Montpellier I, France.
authors.forename: L
authors.initials: L
authors.lastname: Lecointe
authors.forename: V
authors.initials: V
authors.lastname: Rolland
authors.forename: L
authors.initials: L
authors.lastname: Pappalardo
authors.forename: M L
authors.initials: ML
authors.lastname: Roumestant
authors.forename: P
authors.initials: P
authors.lastname: Viallefont
authors.forename: J
authors.initials: J
authors.lastname: Martinez
mesh_terms: D000409:Alanine / Q000031:analogs & derivatives / Q000138:chemical synthesis; D002845:Chromatography; D002851:Chromatography, High Pressure Liquid; D013058:Mass Spectrometry; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D013237:Stereoisomerism
chemical_list: C411576:2,4,6-tribromophenylalanine; C411577:2,4,6-trichlorophenylalanine; C011870:beta-(5-hydroxy-2-pyridyl)alanine; D010649:Phenylalanine; D000409:Alanine