title: Detection of 23 immunogenic pneumococcal proteins using convalescent-phase serum.
abstract: A genomic expression library of Streptococcus pneumoniae was screened with a convalescent-phase serum for immunoreactive proteins. Six known and 17 unknown pneumococcal proteins were detected. Five of the known proteins were surface-located virulence factors, and eight of the unknown proteins were putative membrane proteins.
authors.affiliation: Department of Medical Microbiology and Virology, University of Duesseldorf, Duesseldorf, Germany. zysk@uni-duesseldorf.de
authors.forename: G
authors.initials: G
authors.lastname: Zysk
authors.forename: R J
authors.initials: RJ
authors.lastname: Bongaerts
authors.forename: E
authors.initials: E
authors.lastname: ten Thoren
authors.forename: G
authors.initials: G
authors.lastname: Bethe
authors.forename: R
authors.initials: R
authors.lastname: Hakenbeck
authors.forename: H P
authors.initials: HP
authors.lastname: Heinz
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood*; D000942:Antigens, Bacterial / Q000302:isolation & purification*; D001426:Bacterial Proteins / Q000276:immunology / Q000302:isolation & purification*; D003289:Convalescence; D008565:Membrane Proteins / Q000276:immunology / Q000302:isolation & purification*; D011008:Pneumococcal Infections / Q000276:immunology*; D014774:Virulence
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D008565:Membrane Proteins