title: Use of gamma-carboxy-alpha,beta-unsaturated aldehydes as synthetic equivalents of beta,gamma-unsaturated aldehydes in a novel stereoselective approach to diketides
abstract: [reactions: see text] A two-step aldol/Pd-catalyzed formate reduction sequence allows for convenient, stereoselective access to products of great potential in synthetic approaches to polyketides. A novel diastereoselective Pd-catalyzed formate reduction of allylic acetates is reported.
authors.affiliation: Department of Chemistry, University of Toronto, Ontario, Canada.
authors.initials: G
authors.lastname: Hughes
authors.initials: M
authors.lastname: Lautens
authors.initials: C
authors.lastname: Wen