title: Anticandidal activity of certain South Indian medicinal plants.
abstract: The anticandidal activity of 20 household South Indian medicinal plants and/or plant products was studied using 30 Candida albicans isolates obtained from vaginal candidiasis patients of Rajah Muthiah Medical College and Hospital and compared with the anticandidal activity of garlic. Water and ethanol extracts were prepared and their minimum inhibitory concentrations (MIC) and minimum fungicidal concentrations (MFC) were determined. Water extracts of three plants did not show any anticandidal activity, while Murrya koenigii did not exhibit any anticandidal activity in either extract. Other plants exhibited more activity in ethanol extracts showing that their active principle is more soluble in a non-polar solvent.
authors.affiliation: Department of Biochemistry, Annamalai University, Annamalainagar - 608 002, Tamil Nadu, India.
authors.forename: J
authors.initials: J
authors.lastname: Vaijayanthimala
authors.forename: C
authors.initials: C
authors.lastname: Anandi
authors.forename: V
authors.initials: V
authors.lastname: Udhaya
authors.forename: K V
authors.initials: KV
authors.lastname: Pugalendi
mesh_terms: D000490:Allium; D000935:Antifungal Agents / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects* / Q000302:isolation & purification; D002181:Candidiasis, Vulvovaginal / Q000382:microbiology*; D002212:Capsicum; D002366:Cassia; D020448:Ericales; D005260:Female; D006801:Humans; D007194:India; D008825:Miconazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves; D010946:Plants, Medicinal; D019666:Rubiaceae; D013045:Species Specificity
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts; D008825:Miconazole