Extrahepatic manifestations of chronic hepatitis C.
A by-product of increasing experience with patients infected with the hepatitis C virus is the awareness of a variety of extrahepatic syndromes that seem to be associated with HCV infection. Recent investigations into the relationship between the hepatitis C virus and human cells, particularly lymphocytes, have resulted in possible pathophysiological interactions that may begin to explain some of the extrahepatic manifestations of hepatitis C virus infection. In this review, we will discuss some of the potential interactions from both pathophysiological and clinical viewpoints.
Killenberg
P G
PG
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000175:diagnosis / Q000453:epidemiology; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000453:epidemiology; D015897:Comorbidity; D003449:Cryoglobulinemia / Q000453:epidemiology; D003937:Diagnosis, Differential; D004700:Endocrine System Diseases / Q000453:epidemiology; D005260:Female; D005356:Fibromyalgia / Q000453:epidemiology; D018937:Hepatitis C Antibodies / Q000032:analysis*; D019698:Hepatitis C, Chronic / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007674:Kidney Diseases / Q000453:epidemiology; D008206:Lymphatic Diseases / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D018570:Risk Assessment; D012871:Skin Diseases / Q000453:epidemiology
D001323:Autoantibodies; D018937:Hepatitis C Antibodies