Caesarean section in previously untreated acute promyelocytic leukaemia. Report of two patients.
Acute promyelocytic leukaemia (APL) is characterised by a life-threatening hemorrhagic diathesis which is attributed to a DIC-like coagulopathy. This report describes the problems of childbirth in two patients with untreated APL. It is concluded that caesarean section can be performed without major complications. A prerequisite is an active treatment of the coagulopathy and a close collaboration between the obstetrician and the haematologist.
Celsing
F
F
Division of Hematology, Department of Medicine, Karolinska Hospital and Institute, Stockholm, Sweden. Fred@divmed.ks.de
Ekman
G
G
Granström
L
L
Johnsson
H
H
Björkholm
M
M
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D016026:Bone Marrow Transplantation; D002585:Cesarean Section; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications / Q000628:therapy*; D010348:Patient Care Team; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000628:therapy*; D033581:Stem Cell Transplantation; D014182:Transplantation, Autologous; D014212:Tretinoin / Q000627:therapeutic use
D000970:Antineoplastic Agents; D014212:Tretinoin