[Primary liposarcoma of the stomach wall--a rare mesenchymal tumor].
BACKGROUND
Primary liposarcoma of the stomach wall is rare. Only eight cases have been described so far.


METHODS
Here we report the ninth case, occurring in a 74-year-old woman who presented with weight loss and a therapy-resistant ulcer of the stomach wall.


RESULTS
Pre- and perioperative findings suggested a benign lipoma of the stomach wall. The patient was treated with subtotal gastrectomy. On microscopic examination the tumor showed features of a benign lipoma but for a distinctive capillary net. Immunohistochemically the S-100 reaction was positive. Less than 1% of Ki67-positive cells could be found, thus suggesting a highly differentiated primary liposarcoma of the stomach wall.


CONCLUSIONS
In situations where the benign or malignant nature of a submucosal lesion cannot be diagnosed with certainty a mesenchymal tumor of the stomach wall has to be included in the differential diagnosis. Here the indication for complete surgical excision and histological workup has to be set widely.
Philipps
B
B
Chirurgische Universitätsklinik und Poliklinik, RWTH Aachen.
Lörken
M
M
Manegold
E
E
Kasperk
R
R
Schumpelick
V
V
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D005743:Gastrectomy; D006801:Humans; D019394:Ki-67 Antigen / Q000032:analysis; D008080:Liposarcoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D009418:S100 Proteins / Q000032:analysis; D013270:Stomach / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*
D014408:Biomarkers, Tumor; D019394:Ki-67 Antigen; D009418:S100 Proteins