Candida albicans chorioamnionitis associated with preterm labor and sudden intrauterine demise of one twin. A case report.
BACKGROUND
Although cervicovaginal Candida infections occur in 20-25% of pregnancies, the incidence of ascending infection in these cases is only 0.8%, and such infection rarely causes chorioamnionitis.


METHODS
Sudden intrauterine fetal demise (IUFD) of twin A occurred in a diabetic primigravida presenting with a twin pregnancy and preterm labor at 33 weeks of gestation. Placental pathology and autopsy of the stillborn twin revealed extensive chorioamnionitis and fetal sepsis in the presence of Candida albicans. Twin B was unaffected.


CONCLUSIONS
In this case, C albicans chorioamnionitis seemed to be associated with sudden IUFD.
Friebe-Hoffmann
U
U
Department of Obstetrics and Gynecology, Magee-Womens Hospital, Pittsburgh, Pennsylvania, USA. rsiukf@mail.magee.edu
Bender
D P
DP
Sims
C J
CJ
Rauk
P N
PN
D000328:Adult; D002176:Candida albicans / Q000302:isolation & purification; D002177:Candidiasis / Q000473:pathology*; D002821:Chorioamnionitis / Q000209:etiology / Q000382:microbiology*; D016640:Diabetes, Gestational / Q000150:complications; D004200:Diseases in Twins; D005260:Female; D005313:Fetal Death / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D011247:Pregnancy; D018805:Sepsis / Q000209:etiology; D014427:Twins