title: [The effect of dolantin used during labor on the fetal heart rate and uterine contraction].
abstract: OBJECTIVE
  To investigate the effect of dolantin on fetus and uterine contraction.
  
  
  METHODS
  Thirty pregnant women under stress, restless or fatigue were given dolantin 100 mg i.m. during the latent phase of labor. Internal fetal heart rate (FHR) monitoring and intrauterine pressure measuring were carried out at 30 minutes, 1 hour and 2 hours after medication.
  
  
  RESULTS
  The baseline FHR showed a decrease 30 minutes after dolantin, and decreased further at 1 and 2 hours though still within normal range. At the same time, the baseline of intrauterine pressure decreased as well at 30 minutes, so hypertonic uterine contractions were improved. One hour later the incoordinate uterine contraction was relieved and the frequency and strength of uterine contraction were enhanced (P < 0.01).
  
  
  CONCLUSIONS
  During labor, especially in latent phase, the use of dolantin may improve the general condition of the women. In spite of the decrease of FHR, no fetal distress occurred. Besides, it may enhance the frequency and strength of uterine contraction and relieve the incoordinate uterine contraction.
authors.affiliation: Beijing Obstetrics and Gynecology Hospital.
authors.forename: G
authors.initials: G
authors.lastname: Zhai
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use; D005260:Female; D006340:Heart Rate, Fetal / Q000187:drug effects*; D006801:Humans; D007745:Labor Onset; D008614:Meperidine / Q000627:therapeutic use*; D011247:Pregnancy; D013312:Stress, Physiological / Q000188:drug therapy; D014590:Uterine Contraction / Q000187:drug effects*
chemical_list: D000701:Analgesics, Opioid; D008614:Meperidine