New clinical data and therapeutic prospects in Cupressaceae pollen allergy.
The authors emphasize, thanks to their clinical data over the last 20 years: The steady increase of allergy to C. sempervirens pollen compared to other pollinosis and to atopy. The frequency of cross-reactivity between C. sempervirens and other pollens belonging to Cupressaceae and Taxodiaceae families, in order, in the absence of a very good standardization and of a purification of this pollen, to try to undertake a sound specific immunotherapy using the most cross-reactive pollen mixed with C. sempervirens extracts. As a matter of fact the partially purified extracts of C. japonica gave the higher incidence (91%) of cross-reactivity. Consequently, a mixture of C. sempervirens and C. japonica extracts was used since 1993 with good results in a double blind study.
Ariano
R
R
Modulo d'Allergologia et Immunologia Clinica, Ospedale di Bordighera, IM, Italy.
Panzani
R C
RC
Saraga
J
J
D000397:Air Pollution / Q000032:analysis; D003429:Cross Reactions / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology / Q000276:immunology* / Q000628:therapy; D007167:Immunotherapy / Q000379:methods; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D011058:Pollen / Q000009:adverse effects* / Q000276:immunology / Q000627:therapeutic use; D013045:Species Specificity; D014197:Trees / Q000145:classification
D010936:Plant Extracts