Michael addition of selenoamides to alpha,beta-unsaturated carbonyl compounds: stereocontrolled synthesis of delta-oxo selenoamides and their reactivity
[reaction: see text] Lithium eneselenolates generated from selenoamides underwent Michael addition to alpha,beta-unsaturated esters and ketones with high diastereoselectivity to give delta-oxo selenoamides in moderate to high yields within a few seconds. Further selective transformations of the delta-oxo selenoamides were also achieved.
Murai
T
Department of Chemistry, Faculty of Engineering, Gifu University, Yanagido, Japan.
Suzuki
A
Ezaka
T
Kato
S