Synthesis of the ezomycin nucleoside disaccharide.
[equation--see text] A protected ezomycin octosyl nucleoside was glycosylated at O-6' with a protected ezoaminuroic acid donor to afford, following several functional group modifications, the title compound 1 ( identical with 4-desamino-4-oxoezomycin A(2)).
Knapp
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S
Department of Chemistry, Rutgers-The State University of New Jersey, Piscataway, New Jersey 08854-8087, USA.
Gore
V K
VK
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D004187:Disaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D006031:Glycosylation; D007202:Indicators and Reagents; D008958:Models, Molecular; D008968:Molecular Conformation; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D004187:Disaccharides; D007202:Indicators and Reagents; D009705:Nucleosides; C039957:ezomycin