Synthesis of the spirocyclic cyclohexadienone ring system of the schiarisanrins.
[structure: see text] Studies on the synthesis of the spirocyclic cyclohexadienone ring system 2 of the schiarisanrin family of natural products 1 are described and were based on the Lewis acid-promoted C-alkylation of the corresponding phenolic precursor.
Coleman
R S
RS
Department of Chemistry, The Ohio State University, Columbus 43210-1185, USA.
Guernon
J M
JM
Roland
J T
JT
D034242:Cyclooctanes; D017705:Lignans / Q000138:chemical synthesis*; D010946:Plants, Medicinal / Q000737:chemistry; D011083:Polycyclic Compounds / Q000138:chemical synthesis*; D013141:Spiro Compounds / Q000138:chemical synthesis / Q000737:chemistry
D034242:Cyclooctanes; D017705:Lignans; D011083:Polycyclic Compounds; D013141:Spiro Compounds; C011105:schizandrin