title: [High pressure technology and examples of its use in the biological sciences].
abstract: A short description of basic types of high pressure apparatuses is presented in view of their application in a research in the biosciences. General tendencies in an evolution of characteristic inter-atomic bonds and their changes under high pressure are shortly reviewed. A complex behaviour of organic macromolecular compounds under pressure is demonstrated by the effects of pressure on proteins (including p--T diagram of proteins denaturation). In consequence, an effect of pressure on the simplest micro-organisms is mentioned and relevant critical pressures of sterilization are presented. Trends in a future application of results of the pressure research in biosciences are discussed.
authors.affiliation: Fyzikální ústav AV CR, lékarské fakulty, Univerzity Karlovy, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Kamarád
authors.forename: M
authors.initials: M
authors.lastname: Cepelková
mesh_terms: D001419:Bacteria; D001669:Biochemical Phenomena; D001671:Biochemistry; D004864:Equipment and Supplies; D006801:Humans; D046911:Macromolecular Substances; D011312:Pressure; D011489:Protein Denaturation
chemical_list: D046911:Macromolecular Substances