title: Specialized transcription factories within mammalian nuclei.
abstract: Recent evidence suggests that active RNA polymerases are concentrated in discrete 'factories' where they work together on many different templates. The evidence that such factories specialize in the transcription of particular groups of genes is reviewed.
authors.affiliation: Sir William Dunn School of Pathology, University of Oxford, UK.
authors.forename: A
authors.initials: A
authors.lastname: Pombo
authors.forename: E
authors.initials: E
authors.lastname: Jones
authors.forename: F J
authors.initials: FJ
authors.lastname: Iborra
authors.forename: H
authors.initials: H
authors.lastname: Kimura
authors.forename: K
authors.initials: K
authors.lastname: Sugaya
authors.forename: P R
authors.initials: PR
authors.lastname: Cook
authors.forename: D A
authors.initials: DA
authors.lastname: Jackson
mesh_terms: D002466:Cell Nucleolus / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism*; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D014157:Transcription Factors / Q000378:metabolism; D014158:Transcription, Genetic / Q000502:physiology*
chemical_list: D014157:Transcription Factors; D012321:DNA-Directed RNA Polymerases