Characterization of antigenically unique influenza C virus strains isolated in Yamagata and Sendai cities, Japan, during 1992-1993.
Three influenza C virus strains (C/Yamagata/1/92, C/Yamagata/1/93 and C/Miyagi/5/93) isolated in Yamagata and Sendai Cities, Japan, between June 1992 and May 1993 were found to possess haemagglutinin-esterase glycoproteins that were antigenically indistinguishable from one another but were clearly different from any previous Japanese isolates. To investigate the origin of the 1992/1993 strains, their antigenic and genetic properties were compared with those of eight strains isolated outside Japan between 1967 and 1982. The results showed that the 1992/1993 isolates were closely related to a virus isolated in Brazil in 1982 (C/SaoPaulo/378/82) and that these viruses (including C/SaoPaulo/378/82) are reassortants that had obtained PB1 and NP genes from a C/Yamagata/26/81-like parent and the other genes from another as yet unidentified parent.
Matsuzaki
Y
Y
Department of Bacteriology, Yamagata University School of Medicine, Iida-Nishi, Yamagata 990-9585, Japan. matsuzaki@med.id.yamagata-u.ac.jp
Mizuta
K
K
Kimura
H
H
Sugawara
K
K
Tsuchiya
E
E
Suzuki
H
H
Hongo
S
S
Nakamura
K
K
D000818:Animals; D000956:Antigens, Viral / Q000235:genetics*; D001483:Base Sequence; D002642:Chick Embryo; D004279:DNA, Viral; D006801:Humans; D009982:Gammainfluenzavirus / Q000145:classification / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D007564:Japan; D008969:Molecular Sequence Data; D014764:Viral Proteins / Q000235:genetics*
D000956:Antigens, Viral; D004279:DNA, Viral; D014764:Viral Proteins