Segregation of separate steps in chromium-catalyzed reactions for convenience and mechanistic analysis
[structure: see text] We have developed an apparatus for carrying out redox-coupled chromium-manganese or chromium-zinc reactions on solid-supported substrates which allows recycling of the stoichiometric reductant. In addition to providing a greatly simplified procedure for these reactions, we observe striking differences in the recyclability of Mn and Zn. A preliminary extension of the methodology to the catalytic coupling of allylchromium reagents with solid-supported aldehydes is also reported.
Hari
A
Department of Chemistry, University of Rochester, New York 14627, USA.
Miller
BL