title: [The use of enterosorbents for preventing and stopping chronic toxic stress in submariners].
abstract: The efficiency of prophylactic intestinal sorbents use (algisorb and activated carbon) to prevent chronic toxic stress was investigated in 20 healthy volunteers (atomic submarine personnel) basing on evaluation of central nervous system functional state, hemodynamics, hepatic detoxicative ability and dynamics of trace elements in urine. It was revealed that intestinal sorbents administration in daily dose of 5 g during 20 days promotes gastrointestinal elimination of toxic compounds (cadmium, bismuth, chrome, molybdenum, lithium). It is accompanied with decrease in organism intoxication evidences: reduction in central nervous system excessive excitation, decrease in functional tension of cardiovascular system, recovery of hepatic detoxicative ability. Algisorb has an advantage over activated carbon that allows to recommend this drug in prophylaxis and arresting of chronic toxic stress in submariners both during interfield period and autonomic sailing.
authors.forename: M B
authors.initials: MB
authors.lastname: Murin
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Belyĭ
authors.forename: V G
authors.initials: VG
authors.lastname: Barchukov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Salenko
mesh_terms: D000293:Adolescent; D000328:Adult; D000464:Alginates / Q000627:therapeutic use; D002606:Charcoal / Q000627:therapeutic use; D002908:Chronic Disease; D004338:Drug Combinations; D016061:Enterosorption / Q000379:methods*; D005965:Glucuronates / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008889:Military Personnel; D011603:Psychophysiology; D012426:Russia; D013312:Stress, Physiological / Q000503:physiopathology / Q000517:prevention & control* / Q000523:psychology / Q000652:urine; D013366:Submarine Medicine
chemical_list: D000464:Alginates; D004338:Drug Combinations; D005965:Glucuronates; C100766:calcium alginate, glucuronic acid drug combination; D002606:Charcoal