[Magnetic resonance axonography (MRX)].
Neuronal fibers, especially axonal fibers, have empirically been implicated in the generation of the observed anisotropism in apparent diffusion within the nervous system. Fast axonal flow is believed to play a main, if not sole, role in producing this observed anisotropy. Given that apparent diffusivity follows a Gaussian distribution, "averaged" diffusion length may be calculated as a function of diffusion coefficient (eigenvalue) and diffusion time. This method can be developed into a non-invasive imaging technique for obtaining an estimate of fast axonal flow in humans, in vivo. In this lecture, one of such technique, magnetic resonance axonography (MRX) is briefly described.
Nakada
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Department of Integrated Neuroscience, University of Niigata.
D001370:Axonal Transport / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008962:Models, Theoretical