title: Inducible and constitutive nucleoside-binding sites in Escherichia coli: differential inhibition by nucleoside analogues.
abstract: Constitutive and inducible nucleoside-binding sites on the surface of the cells of E. coli B have different patterns of inhibition by nucleoside analogues. 1(beta-D-Ribofuranosyl)-4-aminopyrimidine-6-one and isoguanosine preferentially inhibit the inducible binding sites while showdomycin and N(4)-dimethylcytidine interfere more strongly with the constitutive function.
authors.forename: J
authors.initials: J
authors.lastname: Doskocil
authors.forename: A
authors.initials: A
authors.lastname: Holý
mesh_terms: D000241:Adenosine; D001665:Binding Sites; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D003562:Cytidine / Q000031:analogs & derivatives / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism*; D006151:Guanosine / Q000494:pharmacology; D007700:Kinetics; D009705:Nucleosides / Q000378:metabolism* / Q000494:pharmacology; D012787:Showdomycin / Q000494:pharmacology; D013936:Thymidine / Q000378:metabolism
chemical_list: D009705:Nucleosides; D006151:Guanosine; C052204:N(4), O(2')-dimethylcytidine; C008184:isoguanosine; D003562:Cytidine; D012787:Showdomycin; D000241:Adenosine; D013936:Thymidine