Urinary beta-glucuronidase in renal cell carcinoma.
The aim of the paper was to study the urinary beta-glucuronidase activity in 30 patients with renal cell carcinoma (RCC), histopathologically proven after surgery, and 32 healthy subjects taken as controls. Classification of patients was done using the TNM system. A statistically significant increase (p < 0.01) in this enzyme was found in RCC patients, without relation to the changes in the urinary sediment (hematuria, pyuria, bacteriuria) or tumor dissemination. Urinary beta-glucuronidase is a useful marker in the diagnosis of malignant renal tumors.
Rodríguez-Cuartero
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A
Department of Internal Medicine, San Cecilio University Hospital and Mora Lara Medical Research Centre, University of Granada, Spain.
Barcelona-Martín
F
F
Pérez-Blanco
F J
FJ
D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000652:urine*; D005966:Glucuronidase / Q000652:urine*; D006801:Humans; D007680:Kidney Neoplasms / Q000201:enzymology*; D008875:Middle Aged
D005966:Glucuronidase