[Neuroanatomical, neuroradiological and functional magnetic resonance imaging correlates of developmental dyslexia].
Neuropathological data in dyslexia has demonstrated alterations in the symmetry normally present in the planum temporale, as well as microdysgenesis in superficial cortical layers and disruption of the cytoarchitecture in subcortical structures. Neuroradiological and functional neuroimaging studies in dyslexia are consistent with localization of dysfunction to the temporoparietal junction. Present neuropathological and neuroimaging data support the concept that the fundamental problem in developmental dyslexia is a phonologic deficit. Present neuroimaging technology has increased our understanding of the pathophysiology of dyslexia. Functional neuroimaging may allow for the investigation of the effects that treatment of dyslexia has on brain plasticity.
Tuchman
R F
RF
Dan Marino Center, Department of Neurology, Miami Children's Hospital, Florida, USA. tuchman@compuserve.com
D002648:Child; D002675:Child, Preschool; D004410:Dyslexia / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009473:Neuronal Plasticity / Q000502:physiology; D010296:Parietal Lobe / Q000473:pathology* / Q000503:physiopathology; D013702:Temporal Lobe / Q000473:pathology* / Q000503:physiopathology