Fetal hydantoin syndrome with rheumatic valvular heart disease.
Research has shown that anticonvulsants are teratogens and pose a risk for fetal malformations. Though Fetal Hydantoin Syndrome (FHS) was first reported by Langhman and others, wide phenotypic variability of this syndrome has lead many clinicians to question its very existence. We report a twelve year old girl with FHS with rheumatic valvular heart disease.
Godbole
K G
KG
Department of Pediatrics, B.J. Medical College, Pune, Maharashtra.
Gambhir
P S
PS
Deshpande
A S
AS
Kurlekar
S U
SU
Phadke
M A
MA
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000927:Anticonvulsants / Q000009:adverse effects*; D002648:Child; D005260:Female; D006228:Hand Deformities, Congenital / Q000139:chemically induced; D006801:Humans; D008607:Intellectual Disability / Q000139:chemically induced; D009264:Nails, Malformed / Q000139:chemically induced / Q000151:congenital*; D010672:Phenytoin / Q000009:adverse effects*; D012214:Rheumatic Heart Disease / Q000150:complications; D013577:Syndrome
D000927:Anticonvulsants; D010672:Phenytoin