A ROMPGEL-supported N-hydroxysuccinimide: a host of acylations with minimal purification
[reaction: see text] A novel N-hydroxysuccinimide ring-opening metathesis polymer is described as a recyclable supported acyl transfer reagent. Amides, carbamates, ureas, Weinreb amides, and hydroxamic acids are all obtained in excellent yields and purities from amines with minimal purification.
Barrett
AG
Department of Chemistry, Imperial College of Science, Technology and Medicine, London, United Kingdom. agmb@ic.ac.uk
Cramp
SM
Roberts
RS
Zecri
FJ