title: Synthesis of functionalized oxazolines and oxazoles with DAST and Deoxo-Fluor.
abstract: [formula: see text] A mild and highly efficient cyclization of beta-hydroxy amides to oxazolines is described using DAST and Deoxo-Fluor reagents. A one-pot protocol for the synthesis of oxazoles from beta-hydroxy amides is also presented.
authors.affiliation: Department of Chemistry, University of Pittsburgh, Pennsylvania 15260, USA.
authors.forename: A J
authors.initials: AJ
authors.lastname: Phillips
authors.forename: Y
authors.initials: Y
authors.lastname: Uto
authors.forename: P
authors.initials: P
authors.lastname: Wipf
authors.forename: M J
authors.initials: MJ
authors.lastname: Reno
authors.forename: D R
authors.initials: DR
authors.lastname: Williams
mesh_terms: D004048:Diethylamines / Q000737:chemistry*; D005461:Fluorine / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry*; D010080:Oxazoles / Q000138:chemical synthesis*
chemical_list: D004048:Diethylamines; D007202:Indicators and Reagents; D010080:Oxazoles; D005461:Fluorine; C040394:diethylaminosulfur trifluoride