Involvement of the entire spinal cord and medulla oblongata in acute catastrophic-onset transverse myelitis in SLE.
A 30-year-old Caucasian male with systemic lupus erythematosus suffered acute catastrophic-onset transverse myelitis. Two years earlier aseptic meningitis, another rare CNS lupus manifestation, had been diagnosed. MRI showed involvement of the medulla oblongata and the entire spinal cord. Therapy with intravenous high-dose methylprednisolone and intravenous cyclophosphamide is discussed.
Neumann-Andersen
G
G
Department of Rheumatology, University Hospital of Umeå, Sweden. Gieann98@student.umu.se
Lindgren
S
S
D000208:Acute Disease; D000328:Adult; D002388:Catastrophic Illness; D003520:Cyclophosphamide / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D007262:Infusions, Intravenous; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008297:Male; D008526:Medulla Oblongata / Q000473:pathology*; D008582:Meningitis, Aseptic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D008775:Methylprednisolone / Q000008:administration & dosage; D009188:Myelitis, Transverse / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013116:Spinal Cord / Q000473:pathology*
D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D008775:Methylprednisolone