The potential use of polymer gel dosimetry in boron neutron capture therapy.
Polymer gels with and without 60 ppm of 10B were exposed to an epithermal neutron beam produced by the Dynamitron at the University of Birmingham on two separate occasions. Eight vials containing the gel, four with and four without boron, were irradiated in pairs in a water phantom for 5 h. The maximum dose was calculated to be 9 Gy in A-150 tissue equivalent plastic, 4 cm deep in the phantom. Measurements were made of the variation of relaxation rates of the gels with depth in a phantom. These were compared with calculations using the MCNP Monte Carlo program and the gel response followed the general trend of the results of the calculations. The calculations showed that the absence of boron gave 66.1% and 44.3% of the absorbed dose with boron and the measurements showed the response of the gel without boron to give 65+/-2% and 41+/-6% of the response with boron for the two halves of the first vial. All the gel measurements showed an enhancement in absorbed dose when boron was added. These results indicate that polymer gels may have a role in measuring the enhancement of absorbed dose due to boron in an epithermal or thermal neutron.
Farajollahi
A R
AR
Department of Medical Physics, Leicester Royal Infirmary NHS Trust, UK.
Bonnett
D E
DE
Tattam
D
D
Green
S
S
D016754:Boron Neutron Capture Therapy / Q000295:instrumentation* / Q000379:methods*; D002138:Calibration; D004307:Dose-Response Relationship, Radiation; D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011874:Radiometry / Q000379:methods*