Serologic detection of adenoviral hemorrhagic disease in black-tailed deer in California.
An enzyme-linked immunosorbent assay (ELISA) and a serum neutralization (SN) test were developed to measure serum antibodies against the adenovirus causing hemorrhagic disease in free-ranging and captive experimentally-infected black-tailed deer (Odocoilenus hemionus columbianus) in California (USA). There was a strong (rho = 0.874) and significant (P < 0.0001) correlation between ELISA and SN titers, although the SN assay was more sensitive than the ELISA.
Lapointe
J M
JM
Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California at Davis, 95616, USA. lapoije@medvet.umontreal.ca
Woods
L W
LW
Lehmkuhl
H D
HD
Keel
M K
MK
Rossitto
P V
PV
Swift
P K
PK
MacLachlan
N J
NJ
D000257:Adenoviridae Infections / Q000175:diagnosis / Q000276:immunology / Q000662:veterinary*; D000818:Animals; D000835:Animals, Wild; D000836:Animals, Zoo; D000914:Antibodies, Viral / Q000097:blood*; D002140:California; D003670:Deer; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D006470:Hemorrhage / Q000175:diagnosis / Q000276:immunology / Q000662:veterinary* / Q000821:virology; D017921:Mastadenovirus / Q000276:immunology*; D009500:Neutralization Tests / Q000662:veterinary; D011817:Rabbits
D000914:Antibodies, Viral