Getting to the point with myosin VI.
The recent observation that class VI myosins move in a direction opposite to all other known myosins, taken together with analyses of mutant flies and mice, suggests that, instead of moving vesicles out towards the cell periphery, myosin VI more likely brings materials or membranes into the cell.
Titus
M A
MA
Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis 55455, USA. titus@lenti.med.umn.edu
D000199:Actins / Q000378:metabolism; D000818:Animals; D002460:Cell Line; D016764:Cell Polarity; D003599:Cytoskeleton / Q000502:physiology*; D004330:Drosophila; D051379:Mice; D008817:Mice, Mutant Strains; D020409:Molecular Motor Proteins / Q000502:physiology*; D009154:Mutation; D009210:Myofibrils / Q000502:physiology; D018995:Myosin Heavy Chains / Q000502:physiology*
D000199:Actins; D020409:Molecular Motor Proteins; C089785:myosin VI; D018995:Myosin Heavy Chains