title: Protein phosphatase 2A: a definite player in viral and parasitic regulation.
abstract: Cells use phosphorylation/dephosphorylation mechanisms to regulate the activity of several proteins required to transmit information from the cell surface to the nucleus. Recent studies have significantly increased our knowledge regarding the structure/function of one major regulator of cell phosphorylation: protein phosphatase 2A (PP2A). This review will discuss the role of PP2A in virology and parasitology.
authors.affiliation: Laboratoire de signalisation immuno-parasitaire, département d'immunologie, Institut Pasteur, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Garcia
authors.forename: X
authors.initials: X
authors.lastname: Cayla
authors.forename: E
authors.initials: E
authors.lastname: Sontag
mesh_terms: D000818:Animals; D056890:Eukaryota / Q000254:growth & development / Q000378:metabolism*; D005786:Gene Expression Regulation; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism; D010749:Phosphoprotein Phosphatases / Q000737:chemistry / Q000378:metabolism*; D010766:Phosphorylation; D011493:Protein Kinase C / Q000378:metabolism; D051744:Protein Kinase C-epsilon; D054648:Protein Phosphatase 2; D015398:Signal Transduction; D014780:Viruses / Q000254:growth & development / Q000378:metabolism*
chemical_list: D007527:Isoenzymes; C497255:PRKCE protein, human; D011493:Protein Kinase C; D051744:Protein Kinase C-epsilon; D010749:Phosphoprotein Phosphatases; D054648:Protein Phosphatase 2