Determination of urinary and serum beta-glucuronidase and alkaline phosphatase in various renal disease and kidney rejection transplanted patients.
Beta-glucuronidase (beta-Glu) and alkaline phosphatase (ALP) were evaluated in serum and urine in 50 subjects classified into five equal groups. Group I was control healthy subjects, while groups II, III, IV, and V were patients with nephritic syndrome, pyelonephritis, kidney rejection, and end-stage renal disease, respectively. Urinary beta-Glu was significantly elevated in all four groups; while serum enzyme showed no change. On the other hand, serum ALP showed a significant elevation in all abnormal groups. Accordingly, urinary beta-Glu and serum ALP could be used as diagnostic markers for various renal diseases.
Refaie
M O
MO
Laboratory of Biochemistry, Faculty of Science, Cairo University, Giza, Egypt.
Abo-Zaid
H
H
Gomma
N A
NA
Aboul-Enein
H Y
HY
D000368:Aged; D000469:Alkaline Phosphatase / Q000032:analysis* / Q000097:blood / Q000652:urine; D004796:Clinical Enzyme Tests; D005069:Evaluation Studies as Topic; D005966:Glucuronidase / Q000032:analysis* / Q000097:blood / Q000652:urine; D006084:Graft Rejection / Q000175:diagnosis; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis*; D007676:Kidney Failure, Chronic / Q000175:diagnosis; D016030:Kidney Transplantation; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000175:diagnosis; D011704:Pyelonephritis / Q000175:diagnosis
D000469:Alkaline Phosphatase; D005966:Glucuronidase