Detection of human herpes virus 6 DNA in fetal hydrops.
Human herpes virus 6 (HHV6) DNA was detected in two of eight fetuses with hydrops and none of ten non-hydropic dead fetuses. Both cases with HHV6 DNA had chromosomal abnormalities. Positive results were confirmed with a second PCR specific for an alternate region of the HHV6 genome. Restriction endonuclease analysis confirmed that the viral DNA was representative of HHV6 type A.
Ashshi
A M
AM
Cooper
R J
RJ
Klapper
P E
PE
Al-Jiffri
O
O
Moore
L
L
D004279:DNA, Viral / Q000302:isolation & purification*; D005260:Female; D016679:Genome, Viral; D005865:Gestational Age; D015654:Herpesvirus 6, Human / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D015160:Hydrops Fetalis / Q000473:pathology / Q000821:virology*; D007231:Infant, Newborn; D008297:Male; D016133:Polymerase Chain Reaction; D015183:Restriction Mapping
D004279:DNA, Viral