title: Ticlopidine plus aspirin for coronary thrombosis in Kawasaki disease.
abstract: Selective inhibitors of the adenosine 5'-diphosphate pathway of platelet activation have been used rarely in children in the United States. We report the successful use of ticlopidine, together with aspirin, in a 7-month-old infant with Kawasaki disease complicated by a thrombus in a giant coronary aneurysm that failed to resolve with thrombolytic therapy. Kawasaki disease, coronary aneurysms, antithrombotic therapy, ticlopidine, children.
authors.affiliation: Department of Cardiology, Children's Hospital, Boston, MA 02115, USA.
authors.forename: M
authors.initials: M
authors.lastname: O'Brien
authors.forename: I A
authors.initials: IA
authors.lastname: Parness
authors.forename: E J
authors.initials: EJ
authors.lastname: Neufeld
authors.forename: A L
authors.initials: AL
authors.lastname: Baker
authors.forename: R P
authors.initials: RP
authors.lastname: Sundel
authors.forename: J W
authors.initials: JW
authors.lastname: Newburger
mesh_terms: D001241:Aspirin / Q000627:therapeutic use*; D003328:Coronary Thrombosis / Q000150:complications / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D013988:Ticlopidine / Q000627:therapeutic use*
chemical_list: D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; D013988:Ticlopidine; D001241:Aspirin