title: Short note: a novel approach for treating early-stage acute leukemias.
abstract: A novel approach to treating acute leukemias is suggested by hypothesizing a focal unique origin in a focal area of bone marrow and this area can be localized (and ablated) before the leukemia stem cells have seeded other bone marrows.
authors.affiliation: Department of Hematology--Oncology, Boston University, School of Medicine, Boston, MA, USA.
authors.forename: D B
authors.initials: DB
authors.lastname: Rubinstein
authors.forename: A I
authors.initials: AI
authors.lastname: Rubinstein
mesh_terms: D000208:Acute Disease; D001853:Bone Marrow / Q000473:pathology*; D006412:Hematopoietic Stem Cells / Q000473:pathology*; D006801:Humans; D007938:Leukemia / Q000209:etiology / Q000473:pathology / Q000628:therapy*