title: [First case of primary IgA glomerulonephritis (Berger's disease) in Senegal].
abstract: Berger's disease or IgA glomerulonephritis is the most common glomerular nephropathy in Europe and represent a rare event in blacks. Here, we describe the case of a 43 years old black Senegalese whose disease was discovered while investigating a persistent proteinuria with high blood pressure and chronic renal failure, but without hematuria. We point out the uncommon feature of this clinical presentation and the importance of bad prognostic factors presented by this patient. We obtained a good outcome by means of converting enzyme inhibitors and corticosteroid therapies: regression of renal failure and normalization of blood pressure. The generalization of renal biopsy practice would lead to a better knowledge of the incidence of this disease among Senegalese people. Indeed, renal biopsy is the main tool to diagnose glomerulonephritis and subsequently adapt the therapy aimed at preventing the possible evolution to end stage renal disease.
authors.affiliation: Clinique Médicale I, CHU A. Le Dantec, Dakar-Sénégal.
authors.forename: B
authors.initials: B
authors.lastname: Diouf
authors.forename: M
authors.initials: M
authors.lastname: Diao
authors.forename: A
authors.initials: A
authors.lastname: Niang
authors.forename: E F
authors.initials: EF
authors.lastname: Ka
authors.forename: T
authors.initials: T
authors.lastname: Moreira Diop
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001707:Biopsy, Needle; D005922:Glomerulonephritis, IGA / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007668:Kidney / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000209:etiology; D008297:Male; D011507:Proteinuria / Q000209:etiology; D012675:Senegal
chemical_list: D000305:Adrenal Cortex Hormones; D000806:Angiotensin-Converting Enzyme Inhibitors