Caffeine during pregnancy? In moderation.
OBJECTIVE
Many of my female patients, those who plan pregnancy or have conceived, are afraid of any intake of caffeine. This often makes their lives miserable during pregnancy. Is this justified scientifically?


CONCLUSIONS
Motherisk's recent meta-analysis suggests that the risks for miscarriage and fetal growth retardation increase only with daily doses of caffeine above 150 mg/d, equivalent to six typical cups of coffee a day. It is possible that some of this presumed risk is due to confounders, such as cigarette smoking.
Koren
G
G
Hospital for Sick Children, Toronto.
D000022:Abortion, Spontaneous / Q000209:etiology; D000818:Animals; D002110:Caffeine / Q000008:administration & dosage / Q000009:adverse effects*; D016022:Case-Control Studies; D003069:Coffee / Q000009:adverse effects; D015331:Cohort Studies; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D006801:Humans; D015201:Meta-Analysis as Topic; D051379:Mice; D016017:Odds Ratio; D011247:Pregnancy; D051381:Rats; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
D003069:Coffee; D002110:Caffeine