title: Ancient DNA-typing approaches for the determination of kinship in a disturbed collective burial site.
abstract: Several DNA-typing approaches are applied for identification and kinship analysis. Autosomal Short Tandem Repeat (STR) typing produces the genetic fingerprint that is unique to an individual. Y-chromosomal STR typing identifies individuals of the same paternal lineage, and sequence analysis of the hypervariable region of the mitochondrion can identify maternally related individuals. The combined approach of these DNA-typing methods allows the determination of kinship even in complex collective burial situations. In a bronze age collective site, the typing methods were tested for applicability to ancient DNA. For each approach, results were obtained, leading to the conclusion that the determination of kinship is achievable.
authors.affiliation: Institute of Zoology and Anthropology, University of Göttingen. tschult@gwdg.de
authors.forename: T
authors.initials: T
authors.lastname: Schultes
authors.forename: S
authors.initials: S
authors.lastname: Hummel
authors.forename: B
authors.initials: B
authors.lastname: Herrmann
mesh_terms: D001842:Bone and Bones / Q000473:pathology; D016172:DNA Fingerprinting; D004272:DNA, Mitochondrial / Q000235:genetics; D005260:Female; D018732:Forensic Anthropology; D005828:Genetics, Population; D005858:Germany; D049690:History, Ancient; D006801:Humans; D008297:Male; D009027:Mortuary Practice; D010164:Paleopathology; D010334:Paternity; D015203:Reproducibility of Results; D014998:Y Chromosome
chemical_list: D004272:DNA, Mitochondrial