[A case of multiple liver metastases from colon cancer successfully operated after intraarterial chemotherapy performed in home].
A 60-year-old male patient had unresectable multiple liver metastases from a sigmoid colon cancer that had been resected, and thus hepatic arterial infusion therapy was planned. A heparin coated catheter was inserted from the left thoracoacromial artery to the proper hepatic artery. 5-fluorouracil (1,000 mg) was administered via the catheter 24 hours/week using an implantable vascular device and a small disposable pump in his home. After 59 weeks, the metastatic liver tumors had decreased remarkably in size, and all tumors could be resected completely through surgery. Three weeks after the operation, the same intraarterial chemotherapy was restarted to prevent the recurrence in the liver. However, the patient died of lymph node recurrences. The intraarterial chemotherapy is thought to be useful for neoadjuvant therapy in patients with inoperable liver metastasis from colon cancer.
Koh
T
T
First Dept. of Surgery, Kyoto Prefectural University of Medicine.
Taniguchi
H
H
Kunishima
S
S
Yamaguchi
A
A
Yamagishi
H
H
D002408:Catheters, Indwelling; D017024:Chemotherapy, Adjuvant; D005472:Fluorouracil / Q000008:administration & dosage*; D006499:Hepatic Artery; D006701:Home Nursing; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012811:Sigmoid Neoplasms / Q000473:pathology*
D005472:Fluorouracil