title: Colocalization of choline acetyltransferase and gamma-aminobutyric acid in the developing and adult turtle retinas.
abstract: Acetylcholine and gamma -aminobutyric acid (GABA) are putative neurotransmitters in the adult vertebrate retina. In this study, cells that coexpress choline acetyltransferase (ChAT) and GABA or glutamic acid decarboxylase (GAD) were investigated in turtle retinas from stage 14 (S14) to adulthood by using a double-labeling immunofluorescence technique. ChAT immunoreactivity was observed at S15 and included not only the presumptive starburst cholinergic amacrine cells but also a population in the ganglion cell layer (GCL) that expressed ChAT transiently during the embryonic stages (see the accompanying paper: Nguyen et al. [2000] J. Comp. Neurol. 420:512-526).
authors.affiliation: The Smith-Kettlewell Eye Research Institute, San Francisco, California 94115, USA.
authors.forename: L T
authors.initials: LT
authors.lastname: Nguyen
authors.forename: N M
authors.initials: NM
authors.lastname: Grzywacz
mesh_terms: D000375:Aging; D000818:Animals; D002795:Choline O-Acetyltransferase / Q000032:analysis*; D005455:Fluorescent Antibody Technique; D005968:Glutamate Decarboxylase / Q000032:analysis; D009024:Morphogenesis; D012160:Retina / Q000196:embryology / Q000254:growth & development / Q000502:physiology*; D014426:Turtles / Q000196:embryology* / Q000254:growth & development*; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
chemical_list: D005680:gamma-Aminobutyric Acid; D002795:Choline O-Acetyltransferase; D005968:Glutamate Decarboxylase