title: Chondromyxoid fibroma of the acromium with soft tissue extension.
abstract: Chondromyxoid fibroma is an unusual, benign tumor of cartilaginous origin and represents less than 1% of all primary bone tumors. It usually involves the long bones around the knee joint or the flat bones of the pelvis or ribs. Soft tissue extension is also thought to be rare in these lesions. They are usually eccentrically located in the metaphyses of the long bones and centrally in the flat bones. The radiographic appearances are characteristically those of a single, lytic lesion with lobulated margins, septations, cortical expansion and a sclerotic rim. Histologically, they display a lobulated pattern with spindle-shaped cells lying within a myxoid matrix with areas of hyaline cartilage. The differential diagnosis includes giant cell tumor, chondroblastoma or enchondroma as well as chondrosarcoma. The rarity of these lesions may render the diagnosis difficult to make, especially when the lesion involves an unusual site such as the acromium.
authors.affiliation: Department of Anatomic Pathology, Sunnybrook and Women's College Health Sciences Centre, Orthopedic and Arthritic Institute, Toronto, Ontario, Canada.
authors.forename: D
authors.initials: D
authors.lastname: Macdonald
authors.forename: V
authors.initials: V
authors.lastname: Fornasier
authors.forename: R
authors.initials: R
authors.lastname: Holtby
mesh_terms: D000174:Acromion / Q000473:pathology*; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D002812:Chondroma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed