[A case of neurogenic dysphagia responding to nitrates].
We described a 47-year-old man with ischemic stroke who developed a brainstem syndrome with persistent dysphagia. He was fed by the nasogastric tube placed intermittently by himself for almost 7 months after the stroke. Elective feeding via percutaneous endoscopic gastrostomy (PEG) was not accepted by the patient. All treatment attempts with benzodiazepines, antidepressants and spasmolytic agents were unsuccessful. Videofluoroscopic investigation revealed excessive and long-lasting spasm of the upper esophageal sphincter which was associated with the massive aspiration of the contrast. The patient dramatically improved after treatment with nitroglycerin and long-acting nitrates with almost complete recovery of normal swallowing. A strikingly good effect of nitrates in the treatment of oropharyngeal dysphagia is emphasized by the authors.
Jamrozik
Z
Z
Klinika Neurologiczna, Akademii Medycznej w Warszawie.
Czyzewski
K
K
Zakrzewska-Pniewska
B
B
Kwieciński
H
H
D002545:Brain Ischemia / Q000150:complications; D001933:Brain Stem / Q000098:blood supply / Q000473:pathology; D003680:Deglutition Disorders / Q000188:drug therapy* / Q000209:etiology; D005774:Gastrostomy / Q000379:methods; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009566:Nitrates / Q000627:therapeutic use*
D009566:Nitrates