Molecular cloning and sequencing of a cDNA encoding the feline cytotoxic T-lymphocyte-associated protein 4 (CTLA4) homologue.
The feline CTLA4 cDNA encodes a transmembrane protein which shares 87.9% sequence identity with the human CTLA4 molecule. The cytoplasmic region of the feline CTLA4 is identical to that of humans and mice, which suggests conserved function(s) such as the regulation of cell-surface expression of this molecule.
Nishimura
Y
Y
University of Bristol Department of Pathology and Microbiology, Homoeopathic Hospital Site, Cotham, Bristol, UK.
Miyazawa
T
T
Ikeda
Y
Y
Izumiya
Y
Y
Nakamura
K
K
Sato
E
E
Mikami
T
T
Takahashi
E
E
D000069594:Abatacept; D000595:Amino Acid Sequence; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000235:genetics*; D001483:Base Sequence; D060908:CTLA-4 Antigen; D002415:Cats; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D018796:Immunoconjugates; D051379:Mice; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid; D013601:T-Lymphocytes
D015703:Antigens, CD; D000943:Antigens, Differentiation; D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; C556707:Ctla4 protein, mouse; D018076:DNA, Complementary; D018796:Immunoconjugates; D000069594:Abatacept