title: [Nasal leishmaniasis in an HIV-positive patient].
abstract: Leishmania is currently one of the most clinically important protozoa in otorhinolaryngology. Mediterranean countries, including Spain, have endemic HIV and L. infantum. Dogs are the most important Leishmania reservoir. Leishmaniasis is transmitted basically by the bite of infected female Phlebotomus sandflies. Its clinical development depends mainly on the host's cellular immunity (TCD4+ lymphocyte count). About 400 cases of HIV-visceral leishmaniasis have been reported in Spain. However, exclusively cutaneous presentation of HIV-leishmaniasis coinfection has been observed in only 2-3% of cases. We report the case of a female HIV+ patient who developed cutaneous leishmaniasis of the nasal vestibule by L. infantum. The patient was treated satisfactorily with a combination of parenteral Pentostam (sodium stilbogluconate) and periodic intralesional injections of Pentostam. The patient was included in a secondary prophylaxis protocol for visceral leishmaniasis with a monthly dose of Glucantime (meglumine antimoniate) for life.
authors.affiliation: Servicio de ORL, Hospital General Universitario Vall d'Hebron, Barcelona, España. 32470jpg@comb.es
authors.forename: J M
authors.initials: JM
authors.lastname: Grasa
authors.forename: J
authors.initials: J
authors.lastname: Lorente
authors.forename: F
authors.initials: F
authors.lastname: Crego
authors.forename: S
authors.initials: S
authors.lastname: Naches
authors.forename: F X
authors.initials: FX
authors.lastname: Subirana
authors.forename: J R
authors.initials: JR
authors.lastname: Calderón
authors.forename: C
authors.initials: C
authors.lastname: Pollán
authors.forename: L F
authors.initials: LF
authors.lastname: Encarnación
authors.forename: P
authors.initials: P
authors.lastname: Quesada
mesh_terms: D000818:Animals; D005260:Female; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D018314:Leishmania infantum; D007896:Leishmaniasis / Q000188:drug therapy / Q000469:parasitology*; D008875:Middle Aged; D015508:Nasal Obstruction / Q000469:parasitology; D009668:Nose Diseases / Q000188:drug therapy / Q000469:parasitology*