An enantioconvergent route to (-)-shikimic acid via a palladium-mediated elimination reaction.
[reaction--see text] (-)-Shikimic acid, the key intermediate in the shikimate pathway in plants and microorganisms, has been synthesized in an enantioconvergent manner from both enantiomeric starting materials by employing a palladium-mediated elimination reaction as the key step.
Yoshida
N
N
Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan.
Ogasawara
K
K
D007202:Indicators and Reagents; D008958:Models, Molecular; D008968:Molecular Conformation; D010165:Palladium; D010944:Plants / Q000378:metabolism; D012765:Shikimic Acid / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
D007202:Indicators and Reagents; D012765:Shikimic Acid; D010165:Palladium