title: A new member of the AKH/RPCH family that stimulates locomotory activity in the firebug, Pyrrhocoris apterus (Heteroptera).
abstract: A new member of the AKH/RPCH family was isolated and identified from the corpora cardiaca of the firebug Pyrrhocoris apterus. The peptide was isolated in a single step by reversed phase HPLC and the structure deduced from the multiple MS (MS(N)) electrospray mass spectra and amino acid analysis as that of an octapeptide with the sequence pGlu-Leu-Asn-Phe-Thr-Pro-Asn-Trp-NH(2): this sequence was confirmed by synthesis. The synthetic peptide induced lipid mobilisation and stimulated locomotory activity in macropterous females. This peptide, designated as Pyrrhocoris apterus adipokinetic hormone (Pya-AKH), is the first identified adipokinetic hormone described in a representative species of the suborder Heteroptera.
authors.affiliation: Institute of Entomology, Academy of Sciences, Branisovská 31, CZ-370 05, Ceské Budejovice, Czech Republic.
authors.forename: D
authors.initials: D
authors.lastname: Kodrík
authors.forename: R
authors.initials: R
authors.lastname: Socha
authors.forename: P
authors.initials: P
authors.lastname: Simek
authors.forename: R
authors.initials: R
authors.lastname: Zemek
authors.forename: G J
authors.initials: GJ
authors.lastname: Goldsworthy
mesh_terms: D000818:Animals; D020062:Heteroptera / Q000502:physiology*; D007301:Insect Hormones / Q000302:isolation & purification / Q000502:physiology*; D009043:Motor Activity / Q000502:physiology*; D009479:Neuropeptides / Q000302:isolation & purification / Q000502:physiology*; D009842:Oligopeptides / Q000302:isolation & purification / Q000502:physiology*; D011761:Pyrrolidonecarboxylic Acid / Q000031:analogs & derivatives
chemical_list: D007301:Insect Hormones; D009479:Neuropeptides; D009842:Oligopeptides; C044833:adipokinetic hormone; C022059:red pigment-concentrating hormone; D011761:Pyrrolidonecarboxylic Acid