title: Urinary continence following posterior urethral valves treatment.
abstract: This retrospective study discusses the incidence of symptomatic voiding dysfunction, the etiological factors and the changes with age and with increasing duration of follow up in 67 boys treated for posterior urethral valves and followed up for a period ranging from 1-21 years. Twenty three of the 67 patients (34.3%) had symptomatic voiding dysfunction; the commonest symptom being nocturnal enuresis with diurnal urgency and frequency. Data in this study suggests a definite decrease in the incidence of urinary incontinence as the patient grows older or as the duration of follow up after valve fulguration increases. A Tc-99m DRCG based uroflowmetry was available in 31 of the 67 patients at the time of this review and evidence of detrusor dysfunction was identified in 9 of the 31 patients on the basis of uroflowmetry. Of significance was the detection of detrusor dysfunction on uroflowmetry in 3 patients with a history of normal urinary control and urinary stream with persistent post treatment hydroureteronephrosis eventually culminating into renal failure. Imipramine therapy was given to 10 of the 17 patients with symptoms of urinary frequency, urgency and nocturnal enuresis with a significantly symptomatic improvement in 9 of these patients. Urinary incontinence, detrusor dysfunction and its effect on the upper tracts and renal function is a significant determinant of the long term outcome of the boys treated for posterior urethral valves and this paper emphasises on the need to carefully evaluate and treat this aspect of all valve patients.
authors.affiliation: Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi.
authors.forename: R
authors.initials: R
authors.lastname: Lal
authors.forename: V
authors.initials: V
authors.lastname: Bhatnagar
authors.forename: D K
authors.initials: DK
authors.lastname: Mitra
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004775:Enuresis / Q000188:drug therapy / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D015994:Incidence; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D013667:Technetium; D014521:Urethra / Q000002:abnormalities* / Q000601:surgery*; D014549:Urinary Incontinence / Q000188:drug therapy* / Q000209:etiology; D013521:Urologic Surgical Procedures, Male
chemical_list: D013667:Technetium; D007099:Imipramine