title: Structural diversity based on cyclopropane scaffolds
abstract: [structure: see text] A practical and efficient route for the stereoselective conversion of easily accessible homoallylic alcohols to diastereomerically pure cis- and trans-disubstituted and 1,2,3-trisubstituted cyclopropanes has been developed. The diversity of structures that can be prepared and the simplicity of the overall sequence make this route ideal for extension to solid-phase synthesis techniques and ultimately combinatorial library generation.
authors.affiliation: Department of Chemistry and Biochemistry, University of Notre Dame, Indiana 46556-5670, USA. taylor.61@nd.edu
authors.initials: RE
authors.lastname: Taylor
authors.initials: MJ
authors.lastname: Schmitt
authors.initials: H
authors.lastname: Yuan