Non-enveloped viruses transmitted by blood and blood products.
Since the advent of solvent detergent (S-D) treatment for inactivation of enveloped viruses, there has been no transmission of human immunodeficiency virus, hepatitis B virus, or hepatitis C virus by treated blood products. However, shortly after the introduction of S-D treatment, transmission of hepatitis A with S-D treated factor concentrates was reported in Germany, Italy, Ireland, the United States and South Africa, and this raised awareness of the potential for blood transmission of non-enveloped viruses in general. This report summarizes the physical and epidemiological features of three non-enveloped viruses, hepatitis A virus, parvovirus B19, and the recently identified TT virus, and their transmission by blood and blood products.
Robertson
B H
BH
Hepatitis Branch A-33, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Erdman
D D
DD
D001688:Biological Products; D018136:Circoviridae; D018173:Circoviridae Infections / Q000097:blood / Q000453:epidemiology / Q000635:transmission* / Q000821:virology; D006506:Hepatitis A / Q000097:blood / Q000453:epidemiology / Q000635:transmission* / Q000821:virology; D006507:Hepatovirus; D006801:Humans; D010322:Parvoviridae Infections / Q000097:blood / Q000453:epidemiology / Q000635:transmission* / Q000821:virology; D016732:Parvovirus B19, Human
D001688:Biological Products