title: Lactone synthesis based on atom transfer carbonylation
abstract: [reaction: see text] Five- to seven-membered lactones were prepared from omega-hydroxyalkyl iodides and CO by atom transfer carbonylation without the need for transition metal catalysts. The reaction proceeds via a hybrid radical/ionic mechanism in which the intramolecular alcoholysis of an omega-hydroxyacyl iodide, arising from atom transfer carbonylation, leads to the lactone.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Japan.
authors.initials: S
authors.lastname: Kreimerman
authors.initials: I
authors.lastname: Ryu
authors.initials: S
authors.lastname: Minakata
authors.initials: M
authors.lastname: Komatsu