Utilization of a glucagon infusion in the management of a massive nifedipine overdose.
This case report describes a continuous i.v. infusion of glucagon used to reverse the cardiovascular manifestations of a nifedipine overdose in a patient who presented after a massive nifedipine extended-release tablet ingestion. In this patient, glucagon appeared to be effective in the management of this toxicologic emergency.
Papadopoulos
J
J
Arnold & Marie Schwartz College of Pharmacy, Brooklyn, New York 11201-5497, USA.
O'Neil
M G
MG
D000284:Administration, Oral; D002121:Calcium Channel Blockers / Q000494:pharmacology / Q000506:poisoning*; D003692:Delayed-Action Preparations; D004638:Emergency Treatment / Q000379:methods*; D005751:Gastric Lavage; D005934:Glucagon / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007022:Hypotension / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy*; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000494:pharmacology / Q000506:poisoning*; D013406:Suicide, Attempted
D002121:Calcium Channel Blockers; D003692:Delayed-Action Preparations; D005934:Glucagon; D009543:Nifedipine