[The antibacterial resistance of the strains making up the components of probiotic preparations].
The spectrum of the antibiotic resistance of 21 strains of normal microflora, mainly forming constituents of widely used probiotics to 25 antibacterial preparations. Lactobacillus spp. were prevalent in the strains under test. The spectrum of the antibiotic resistance of lactobacilli varied, the gradation of resistance being more pronounced with respect to strains and not species. Both highly sensitive and highly resistant Lactobacillus strains were found: L. acidophilus (a component of biopreparation "Linex"), L. plantarum 8RA3, L. fermentum 90T4C (probiotic "Lactobacterin"), L. fermentum BL96. Bacteria used as the components of combined preparation "Linex" exhibited the highest resistance to a number of modern antibiotics. Strains of bifidobacteria were found to be highly sensitive to antibiotics.
Lykova
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EA
Medical Center, Head Office of the President of the Russian Federation, Moscow, Russia.
D001644:Bifidobacterium / Q000187:drug effects; D004352:Drug Resistance, Microbial; D016984:Enterococcus faecium / Q000187:drug effects; D007778:Lactobacillus / Q000187:drug effects; D008826:Microbial Sensitivity Tests / Q000706:statistics & numerical data; D019936:Probiotics / Q000494:pharmacology*