Synthesis of N-hydroxy peptides: chemical ligation of O-acyl hydroxamic acids.
[process--see text] A novel chemical ligation process is described that results in the construction of N-hydroxy peptides.
Braslau
R
R
Department of Chemistry, University of California, Santa Cruz, California 95064, USA. braslau@chemistry.ucsc.edu
Axon
J R
JR
Lee
B
B
D000215:Acylation; D003545:Cysteine; D006877:Hydroxamic Acids; D006900:Hydroxylation; D007202:Indicators and Reagents; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry*
D006877:Hydroxamic Acids; D007202:Indicators and Reagents; D010455:Peptides; D003545:Cysteine