Hyperthyroidism complicating asthma treatment.
Asthma is one of the most common chronic medical conditions. The usual treatment includes quick relief bronchodilator medications of the sympathomimetic class and controller medications that may include the long-acting inhaled bronchodilator salmeterol. Mild adverse cardiac and central nervous system effects are common with these medications, requiring modifications in dose or occasionally switching to a different medication. Both asthma and thyroid disease are common disorders that occasionally occur together. Hyperthyroidism may exacerbate asthma. Many symptoms of hyperthyroidism are identical to the adverse effects of the commonly used inhaled bronchodilators and include tremor, nervousness, tachycardia, wide pulse pressure, palpitations, emotional lability, agitation, nightmares, aggressive behavior, and diarrhea. In this report we describe a patient with hyperthyroidism whose symptoms initially were thought to be adverse effects of the inhaled bronchodilator medications.
Zacharisen
M C
MC
Department of Pediatrics, Medical College of Wisconsin, Milwaukee, USA.
Fink
J N
JN
D000368:Aged; D013956:Antithyroid Agents / Q000008:administration & dosage; D001249:Asthma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000008:administration & dosage* / Q000009:adverse effects; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D011441:Propylthiouracil / Q000008:administration & dosage; D012008:Recurrence; D018570:Risk Assessment
D013956:Antithyroid Agents; D001993:Bronchodilator Agents; D011441:Propylthiouracil