[The role of different microorganisms in the genesis of tubal-peritoneal infertility and in immunity].
The character of microflora, directly causing inflammatory process in tuboperitoneal infertility, was studied. The study revealed the prevalence of microbial associations, Chlamydia infection was detected in half of the women, and in 17% of the patients this infection was for the first time detected in the upper section of their reproductive apparatus, which was indicative of the role of Chlamydia infection in the occlusion of the uterine tubes. Opportunistic microflora persisting in persons with defective antimicrobial protection was found. The study of local protective factors in peritoneal fluid revealed the absence of T-cell activity, which was manifested by a low level of sIL-2R and the absence of a significant rise in the level of IL-2 in peritoneal fluid in comparison with that in healthy women. In addition, a decrease in the total complement activity and in the activity of component C3 of the complement was established.
Uzlova
T V
TV
State Medical Academy, Chelyabinsk, Russia.
Teplova
S N
SN
Medvedev
B I
BI
D000328:Adult; D000917:Antibody Formation; D001202:Ascitic Fluid / Q000209:etiology* / Q000276:immunology / Q000382:microbiology / Q000821:virology; D001419:Bacteria / Q000302:isolation & purification*; D002175:Candida / Q000302:isolation & purification*; D002584:Cervix Uteri / Q000382:microbiology / Q000821:virology; D002908:Chronic Disease; D003587:Cytomegalovirus / Q000302:isolation & purification*; D005260:Female; D018258:Herpesvirus 2, Human / Q000302:isolation & purification*; D006801:Humans; D007247:Infertility, Female / Q000209:etiology* / Q000276:immunology / Q000382:microbiology / Q000821:virology; D014599:Uterus / Q000382:microbiology / Q000821:virology