Predictors of long-term weight reduction in obese patients after initial very-low-calorie diet.
This prospective interventional study assessed possible predictors of long-term weight loss and compared them with factors previously identified as predicting short-term variations in weight reduction after initial treatment with a very-low-calorie diet (VLCD). Eighty-two overweight patients with a body mass index of at least 27 kg/m2 were recruited from primary health-care settings into a structured weight-reduction and maintenance program. All patients used the VLCD for 8 weeks and were followed up 13.2 months later. Mean body weight decreased an average of 13.3 kg during the 8-week treatment and was still 8.6 kg below pretreatment levels after 13.2 months. Triglyceride levels were also significantly reduced. Sex, baseline weight, baseline body mass index, and age predicted 37% of the variation in short-term weight loss but had no long-term predictive value.
Høie
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Norsk Legesenter, Oslo, Norway.
Bruusgaard
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D000293:Adolescent; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D004038:Diet, Reducing / Q000379:methods*; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000175:diagnosis / Q000178:diet therapy* / Q000209:etiology; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood; D015431:Weight Loss; D005723:gamma-Glutamyltransferase / Q000097:blood
D014280:Triglycerides; D005723:gamma-Glutamyltransferase