title: N-[[(5-methyl-3-phenylisoxazol-4-yl)-phenyl]sulfonyl]propanamide, sodium salt, parecoxib sodium: A potent and selective inhibitor of COX-2 for parenteral administration.
authors.affiliation: Searle Research and Development, 700 Chesterfield Parkway, St. Louis, Missouri 63198, and 4901 Searle Parkway, Skokie, Illinois 60077, USA. john.j.talley@monstanto.com
authors.forename: J J
authors.initials: JJ
authors.lastname: Talley
authors.forename: S R
authors.initials: SR
authors.lastname: Bertenshaw
authors.forename: D L
authors.initials: DL
authors.lastname: Brown
authors.forename: J S
authors.initials: JS
authors.lastname: Carter
authors.forename: M J
authors.initials: MJ
authors.lastname: Graneto
authors.forename: M S
authors.initials: MS
authors.lastname: Kellogg
authors.forename: C M
authors.initials: CM
authors.lastname: Koboldt
authors.forename: J
authors.initials: J
authors.lastname: Yuan
authors.forename: Y Y
authors.initials: YY
authors.lastname: Zhang
authors.forename: K
authors.initials: K
authors.lastname: Seibert
mesh_terms: D000215:Acylation; D000818:Animals; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000008:administration & dosage / Q000494:pharmacology*; D004285:Dogs; D007267:Injections; D007527:Isoenzymes / Q000037:antagonists & inhibitors* / Q000494:pharmacology*; D007555:Isoxazoles / Q000008:administration & dosage / Q000494:pharmacology*; D008252:Macaca fascicularis; D008297:Male; D011451:Prostaglandin-Endoperoxide Synthases / Q000494:pharmacology*; D051381:Rats
chemical_list: D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D007527:Isoenzymes; D007555:Isoxazoles; C409945:parecoxib; D051546:Cyclooxygenase 2; D011451:Prostaglandin-Endoperoxide Synthases