title: C2-symmetric planar chiral ferrocene diamides by (-)-sparteine-mediated directed ortho-lithiation. Synthesis and catalytic activity
abstract: [reaction: see text] A variety of highly enantioenriched singly and doubly (4) functionalized derivatives of 1,1'-N,N,N',N'-tetraisopropylferrocenedicarboxamide 1 have been synthesized by (-)-sparteine (2)-mediated directed ortho-metalation and Pd-catalyzed cross coupling reactions. The synthetic applications of these chiral ligands in asymmetric alkylation of benzaldehyde and Pd(0)-catalyzed allylic substitution have been demonstrated.
authors.affiliation: The Guelph-Waterloo Centre for Graduate Work in Chemistry, University of Waterloo, Ontario, Canada.
authors.initials: RS
authors.lastname: Laufer
authors.initials: U
authors.lastname: Veith
authors.initials: NJ
authors.lastname: Taylor
authors.initials: V
authors.lastname: Snieckus