title: Effect of CT-based treatment planning on portal field size and outcome in radiation treatment of localized prostate cancer.
abstract: The portal field sizes of 361 consecutive patients treated with curative radiotherapy for localized prostate cancer were measured. The introduction of CT-based information resulted in a significant increase of field sizes, leading to an almost doubling of the treated volume, some increase in late rectal toxicity, but also in local control.
authors.affiliation: Department of Radiation Oncology, Academic Hospital Vrije Universiteit, De Boelelaan 1117, 1081 HV, Amsterdam, Netherlands.
authors.forename: J W
authors.initials: JW
authors.lastname: Mens
authors.forename: B J
authors.initials: BJ
authors.lastname: Slotman
authors.forename: O W
authors.initials: OW
authors.lastname: Meijer
authors.forename: H A
authors.initials: HA
authors.lastname: Langendijk
mesh_terms: D000206:Actuarial Analysis; D000368:Aged; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D018572:Disease-Free Survival; D019583:Dose Fractionation, Radiation; D005500:Follow-Up Studies; D006801:Humans; D008198:Lymph Nodes / Q000528:radiation effects; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D009367:Neoplasm Staging; D010388:Pelvis; D011467:Prostate / Q000000981:diagnostic imaging; D017430:Prostate-Specific Antigen / Q000032:analysis; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D011882:Radiotherapy, High-Energy / Q000009:adverse effects / Q000379:methods; D012007:Rectum / Q000528:radiation effects; D012189:Retrospective Studies; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D001743:Urinary Bladder / Q000528:radiation effects
chemical_list: D017430:Prostate-Specific Antigen