title: [Effect of menstrual cycle on Doppler measurements of adnexa tumors].
abstract: In a collective of 80 premenopausal women presenting with a total of 83 adnexal masses we tried to find out whether there is any influence on Doppler results by the phase of menstrual cycle. All measurements were performed with a 5.0 MHz transvaginal probe of an Acuson 125 Xp10 between April 1993 and September 1998. In 39 tumours measurements were performed during the follicular phase, in 44 tumours during the luteal phase. Histopathological evaluation showed 72 benign and 11 malignant adnexal masses. A cut-off of 0.69 for PI and 0.45 for RI was used to differentiate preoperatively between benign and malignant masses. In the follicular phase was a sensitivity of 40% and a specificity of 76.5% for RI. Referring values for PI were 60% and 70.6%. In the luteal phase RI led to a sensitivity of 83.3% and a specificity of 71.1%. Regarding PI a sensitivity of 100% and a specificity of 68.4% was achieved. There was no statistically significant difference when sensitivity and specificity for both parameters were compared in the two phases of menstrual cycle. These results are in contrast to the hypothesis that Corpora lutea are responsible for a higher degree of false positive results during the luteal phase. We therefore think that there is no advantage in performing Doppler measurements strictly during the follicular phase.
authors.affiliation: Universitäts-Frauenklinik Aachen. Brigitte.Leeners@post.rwth-aachen.de
authors.forename: B
authors.initials: B
authors.lastname: Leeners
authors.forename: A
authors.initials: A
authors.lastname: Funk
authors.forename: W
authors.initials: W
authors.lastname: Rath
mesh_terms: D000328:Adult; D003338:Corpus Luteum / Q000000981:diagnostic imaging; D019160:Endosonography; D005189:False Positive Reactions; D005260:Female; D005498:Follicular Phase / Q000502:physiology; D006801:Humans; D008183:Luteal Phase / Q000502:physiology; D008597:Menstrual Cycle / Q000502:physiology*; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging*; D018615:Ultrasonography, Doppler, Color