A case of hypothalamic adrenal insufficiency manifested normal ACTH response to insulin-induced hypoglycemia.
A low plasma ACTH response to insulin-induced hypoglycemia and an exaggerated and delayed plasma ACTH response to CRH stimulation have been considered as an indicator of hypothalamic hypopituitarism. We report a case of hypothalamic adrenal insufficiency which manifested normal ACTH response to insulin-induced hypoglycemia. This case provides important information to categorize hypothalamic adrenal insufficiency caused by abnormal regulation of CRH release.
Hasegawa
G
G
The First Department of Internal Medicine, Kyoto Prefectural University of Medicine, Japan.
Ashihara
E
E
D000307:Adrenal Gland Diseases / Q000097:blood*; D000324:Adrenocorticotropic Hormone / Q000097:blood*; D000368:Aged; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced / Q000378:metabolism*; D007027:Hypothalamic Diseases / Q000097:blood*; D007328:Insulin; D012016:Reference Values
D007328:Insulin; D000324:Adrenocorticotropic Hormone