title: The electric and magnetic fields research and public information dissemination (EMF-RAPID) program.
abstract: In the United States, public concern that exposure to power-line fields was linked to cancer led to the establishment of a Congressionally mandated program, the Electric and Magnetic Fields Research and Public Information Dissemination (EMF-RAPID) Program. A major goal of the program was to "determine whether or not exposures to electric and magnetic fields produced by the generation, transmission, and use of electrical energy affect human health". Between 1994 and 1998, the EMF-RAPID program spent approximately $41 million on biological research. Much of the work funded by the EMF-RAPID program has not yet been published in the peer-reviewed literature. The U.S. National Institute of Environmental Health Sciences (NIEHS) asked that Radiation Research publish this special issue in an attempt to remedy this publication gap. The issue includes reviews of studies that were done to assess the biological plausibility of claims that power-frequency fields caused leukemia and breast cancer. The issue continues with two teratology studies and one immunology study. The section of the issue covering in vitro studies begins with an overview of the efforts NIEHS made to replicate a wide range of reported effects of power-frequency fields and continues with four papers reporting the absence of effects of power-frequency fields on the expression of stress-response genes and oncogenes. Other reports of in vitro studies and studies of mechanisms cover cytotoxicity, gap junction intracellular communication, calcium ion transport across the plasma membrane, and intracellular electric fields.
authors.affiliation: Department of Radiation Oncology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Moulder
mesh_terms: D000818:Animals; D001943:Breast Neoplasms / Q000209:etiology*; D015197:Carcinogenicity Tests; D003254:Consumer Advocacy; D004307:Dose-Response Relationship, Radiation; D004559:Electric Wiring; D004574:Electromagnetic Fields / Q000009:adverse effects*; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006078:Government Programs / Q000331:legislation & jurisprudence; D006801:Humans; D007938:Leukemia / Q000209:etiology*; D008297:Male; D009152:Mutagenicity Tests; D010353:Patient Education as Topic / Q000458:organization & administration; D012109:Research Support as Topic / Q000458:organization & administration; D014481:United States