title: Controversies regarding definition of neonatal hypoglycemia: suggested operational thresholds.
abstract: The definition of clinically significant hypoglycemia remains one of the most confused and contentious issues in contemporary neonatology. In this article, some of the reasons for these contentions are discussed. Pragmatic recommendations for operational thresholds, ie, blood glucose levels at which clinical interventions should be considered, are offered in light of current knowledge to aid health care providers in neonatal medicine. Future areas of research to resolve some of these issues are also presented.
authors.affiliation: Division of Neonatology, Department of Pediatrics; Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
authors.forename: M
authors.initials: M
authors.lastname: Cornblath
authors.forename: J M
authors.initials: JM
authors.lastname: Hawdon
authors.forename: A F
authors.initials: AF
authors.lastname: Williams
authors.forename: A
authors.initials: A
authors.lastname: Aynsley-Green
authors.forename: M P
authors.initials: MP
authors.lastname: Ward-Platt
authors.forename: R
authors.initials: R
authors.lastname: Schwartz
authors.forename: S C
authors.initials: SC
authors.lastname: Kalhan
mesh_terms: D000222:Adaptation, Physiological; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000175:diagnosis*; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000097:blood / Q000175:diagnosis*; D012307:Risk Factors
chemical_list: D005947:Glucose