title: [Pilot project for eradicating maedi-visna in Walliser blacknose sheep].
abstract: Maedi-Visna is a lentiviral disease of sheep with a worldwide distribution. The transmission of the virus occurs primarily via colostrum and milk from the infected ewe to its newborn lamb but also horizontally between sheep. The most obvious clinical symptoms are progressive dyspnea and emaciation. In this prospective study an eradication based on serological testing and removing of seropositive animals was performed in 24 flocks of sheep of the breed "Walliser Schwarznasenschafe" leading to a reduction of the seroprevalence from 36% to 1% within two years. The control group consisted of 21 flocks of sheep. Lambs of seropositive ewes had a 7.6 times higher risk to seroconvert within their first two years of life compared to those of seronegative ewes. The dynamics of the spread of the infection were studied in birth cohort groups. Cohort animals of seropositive ewes showed an obvious trend to seroconvert slowly. Seropositive ewes had a significantly lower reproduction rate and their lambs suffered from significantly higher death and lower growth rates, probably due to a reduced milk production, resulting in economic losses.
authors.affiliation: Institut für Veterinär-Virologie, Universität Bern.
authors.forename: P
authors.initials: P
authors.lastname: Scheer-Czechowski
authors.forename: H R
authors.initials: HR
authors.lastname: Vogt
authors.forename: A
authors.initials: A
authors.lastname: Tontis
authors.forename: E
authors.initials: E
authors.lastname: Peterhans
authors.forename: R
authors.initials: R
authors.lastname: Zanoni
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D001947:Breeding; D015331:Cohort Studies; D005260:Female; D015994:Incidence; D008297:Male; D010865:Pilot Projects; D011021:Pneumonia, Progressive Interstitial, of Sheep / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D011446:Prospective Studies; D016036:Seroepidemiologic Studies; D012756:Sheep; D013557:Switzerland / Q000453:epidemiology; D014790:Visna-maedi virus / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral