[The HLA system antigens in delayed sexual development].
Frequency distribution of HLA antigens of A and B loci was examined in 138 adolescent boys aged 14-18 with delayed sexual development (DSD) of stages I-III, residing in the north-eastern region of Ukraine. Increase of A28- and B40-antigens and haplotypes A1-B40, A28-B40, A10-B40 determination frequencies was established. There were revealed positive and negative correlation between some of HLA antigens and DSD. Relative and attributive risks of DSD formation were calculated.
Bagatskaia
N V
NV
Krivich
I P
IP
Demenkova
I G
IG
Kovaleva
V I
VI
D000293:Adolescent; D000483:Alleles; D016009:Chi-Square Distribution; D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D006239:Haplotypes; D006801:Humans; D008297:Male; D010641:Phenotype; D011628:Puberty, Delayed / Q000235:genetics* / Q000276:immunology; D012307:Risk Factors; D014455:Ukraine
D006680:HLA Antigens