title: Serum lipoprotein (a) concentration in patients with nephrotic syndrome and its clinical implication.
abstract: Serum lipoprotein(a) [Lp(a)] concentration was determined in 42 patients with primary nephrotic syndrome (NS) and the relationships between Lp (a) and plasma lipids, apolipoproteins, serum creatinine (Scr), albumin, urinary proteins (Upro) were also analyzed. The results showed that: (1) serum Lp(a) concentrations in the patients with NS were higher than those in healthy controls; (2) the levels of serum Lp(a) were correlated positively with total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), very low density lipoprotein cholesterol (VLDL-C), apolipoprotein B (Apo-B), Upros (Upro). It is concluded that the NS patients had the potential risk of suffering from coronary artery disease, glomerular sclerosis and thrombosis. The remission of NS may partially decrease the serum Lp(a) levels. Further studies are needed to explore the prevention and treatment of dislipedemia in patients with NS.
authors.affiliation: Department of Nephrology, Xiehe Hospital, Tongji Medical University, Wuhan.
authors.forename: X
authors.initials: X
authors.lastname: Yang
authors.forename: H
authors.initials: H
authors.lastname: Wang
authors.forename: Z
authors.initials: Z
authors.lastname: Zhu
authors.forename: A
authors.initials: A
authors.lastname: Deng
mesh_terms: D000328:Adult; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000209:etiology; D006801:Humans; D006949:Hyperlipidemias / Q000209:etiology; D017270:Lipoprotein(a) / Q000097:blood*; D008297:Male; D009404:Nephrotic Syndrome / Q000097:blood* / Q000150:complications; D012307:Risk Factors
chemical_list: D017270:Lipoprotein(a)