title: Prospective study of hair reduction by diode laser (800 nm) with long-term follow-up.
abstract: BACKGROUND
  Multiple laser systems are available for the purpose of hair removal.
  
  
  OBJECTIVE
  The purpose of this study was to determine the safety and long-term efficacy of the 800 nm, pulsed diode laser at reducing hair count.
  
  
  METHODS
  Fifty volunteers, primarily Fitzpatrick skin types II and III, with dark brown or black hair, were treated with a diode laser (800 nm, 10-40 J/cm2, 5-30 msec, 9 mm 9 mm, 5 degrees C chilled handpiece). Each subject had eight treatment sites at varying fluences and pulse durations, as well as a varying number of treatments and pulses. Hair counts were obtained at each site at baseline, 1, 3, 6, 9, and an average of 20 months after treatment.
  
  
  RESULTS
  After one treatment, hair regrowths ranged from 22 to 31% at the 1-month follow-up visit, then remained stable between 65 and 75% from the 3-month to the averaged 20-month follow-up. After two treatments there were relatively longer growth delays, with hair regrowths plateauing beginning at 6 months after treatment and ranging from 47 to 66% for the remainder of the follow-up evaluations. Side effects were limited to pigmentary changes, transient in subjects with skin types II and III.
  
  
  CONCLUSIONS
  This 800 nm diode laser with a chilled sapphire tip and variable pulse duration is safe and effective for long-term hair reduction in individuals with skin types II and III.
authors.affiliation: Laser and Skin Surgery Center of New York, New York, USA.
authors.forename: W W
authors.initials: WW
authors.lastname: Lou
authors.forename: A T
authors.initials: AT
authors.lastname: Quintana
authors.forename: R G
authors.initials: RG
authors.lastname: Geronemus
authors.forename: M C
authors.initials: MC
authors.lastname: Grossman
mesh_terms: D004307:Dose-Response Relationship, Radiation; D005260:Female; D005500:Follow-Up Studies; D006204:Hair Removal / Q000379:methods; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology*; D017496:Hypopigmentation / Q000209:etiology*; D053685:Laser Therapy / Q000009:adverse effects; D008297:Male; D011446:Prospective Studies; D012016:Reference Values; D012880:Skin Pigmentation; D016896:Treatment Outcome