title: Radiobiological depth of subcutaneous induration.
abstract: The incidence of subcutaneous induration in 23 breast cancer patients with postmastectomy radiotherapy was investigated. The patients were treated with three different radiotherapy schedules 7. 9-9.8 years ago. The incidence was correlated with the biological effective dose (BED) at different depths from the skin surface and a best fit was obtained using an alpha/beta ratio of 2 Gy. The most representative depth at which to assess dose for subcutaneous induration was 2 mm which is near the subcutaneous fat/dermis interface.
authors.affiliation: Department of Oncology, Kuopio University Hospital, FIN-70210, Kuopio, Finland.
authors.forename: J
authors.initials: J
authors.lastname: Nuutinen
authors.forename: A
authors.initials: A
authors.lastname: Väänänen
authors.forename: T
authors.initials: T
authors.lastname: Lahtinen
authors.forename: M
authors.initials: M
authors.lastname: Turunen
authors.forename: S
authors.initials: S
authors.lastname: Remes
authors.forename: E
authors.initials: E
authors.lastname: Alanen
mesh_terms: D000368:Aged; D001284:Atrophy; D001943:Breast Neoplasms / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011878:Radiotherapy / Q000009:adverse effects*; D012867:Skin / Q000473:pathology / Q000528:radiation effects*