title: Fatal rupture of the spleen caused by infiltration of T-cell lymphoma.
abstract: Pathological or spontaneous rupture of the spleen has been described in a variety of diseases affecting the spleen, with infections being cited as the cause in most cases. In hematological malignancies it is a rare event, despite the frequent involvement of the spleen in these diseases. It has, however, been described in patients with acute and chronic leukemia, Hodgkin's disease, non-Hodgkin's lymphoma of B-cell origin, mycosis fungoides, and so-called histiocytic lymphoma. Here, we present a fatal case of splenic rupture caused by infiltration of a peripheral T-cell lymphoma, unspecified according to the REAL classification. The importance of a correct diagnosis and fast surgery is emphasized.
authors.affiliation: Department of Hematology, Herlev University Hospital, Denmark.
authors.forename: I
authors.initials: I
authors.lastname: Schiødt
authors.forename: E
authors.initials: E
authors.lastname: Duun
authors.forename: T K
authors.initials: TK
authors.lastname: Fischer
authors.forename: A P
authors.initials: AP
authors.lastname: Christiansen
authors.forename: E
authors.initials: E
authors.lastname: Ralfkiaer
mesh_terms: D017809:Fatal Outcome; D006801:Humans; D016399:Lymphoma, T-Cell / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D013154:Spleen / Q000473:pathology; D013161:Splenic Rupture / Q000209:etiology*