Aggressive granulomatous mycosis fungoides with clinical pulmonary and thyroid involvement.
We report a patient with granulomatous mycosis fungoides (MF) that progressed to a tumoral pattern and finally developed clinical pulmonary and thyroid involvement, despite multiple and intensive treatments. We emphasize the visceral involvement in this case, which was manifest as dyspnoea simulating pneumonia and by palpable thyroid nodules. These features are very unusual even in classic MF, and this is the first case in our knowledge of thyroid involvement in granulomatous MF.
Gómez-De La Fuente
E
E
Department of Dermatology, 12 de Octubre University Hospital, Ctra Andalucía Km 5.4, 28041 Madrid, Spain.
Ortiz
P L
PL
Vanaclocha
F
F
Rodriguez-Peralto
J L
JL
Iglesias
L
L
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006099:Granuloma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008297:Male; D009182:Mycosis Fungoides / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011859:Radiography; D012878:Skin Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000188:drug therapy / Q000556:secondary*; D017211:Treatment Failure