title: Blood glycated hemoglobin evaluation in sick dogs.
abstract: Blood glycated hemoglobin concentration reflects long-term serum glucose levels in dogs. In this study, the effects of several diseases on blood glycated hemoglobin levels have been evaluated. For this study, blood samples were drawn from 93 unhealthy dogs. The animals were distributed into 10 groups according to pathological process (group 1, digestive problems; group 2, leishmaniasis; group 3, anemia; group 4, dermatological disorders; group 5, urinary problems; group 6, cardiorespiratory problems; group 7, diabetes mellitus; group 8, insulinoma; group 9, general diseases; group 10, control group). Blood glucose and glycated hemoglobin concentrations and hemoglobin and hematocrit values were analyzed in all the animals. In diabetic dogs, a strong increase in blood glycated hemoglobin was observed when compared with the other groups (P < 0.01). In contrast, dogs with insulinoma showed a decrease in blood glycated hemoglobin, though significant differences were not reported in all cases. No change in blood glycated hemoglobin concentrations were reported in dogs affected by other diseases. So, we can suppose that only the chronic alterations in glucose metabolism (chronic hyper- or hypoglycemia) can induce significant changes on the blood glycated hemoglobin concentrations in dogs.
authors.affiliation: Department of Animal Pathology, Veterinary Faculty, University of Zaragoza, Spain. cmarca@posta.unizar.es
authors.forename: M C
authors.initials: MC
authors.lastname: Marca
authors.forename: A
authors.initials: A
authors.lastname: Loste
authors.forename: A
authors.initials: A
authors.lastname: Unzueta
authors.forename: M
authors.initials: M
authors.lastname: Pérez
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000097:blood*; D004285:Dogs; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006400:Hematocrit; D006943:Hyperglycemia / Q000150:complications / Q000662:veterinary*; D007003:Hypoglycemia / Q000150:complications / Q000662:veterinary*; D008297:Male
chemical_list: D006442:Glycated Hemoglobin