Electrosynthesis of alpha-arylated beta-substituted cyclopropylphosphonates. Synthesis of a phosphonic analogue of minalcipran
[reaction: see text] The synthesis of alpha-arylated beta-substituted cyclopropylphosphonates was efficiently achieved by electroreduction of diethyl alpha,alpha-dichlorobenzylphosphonate in the presence of Michael acceptors in a one-compartment cell equipped with a magnesium sacrificial anode.
Duquenne
C
Laboratoire d'Heterochimie Organique associe au CNRS, IRCOF, INSA et Universite de Rouen, Mont-Saint-Aignan, France.
Goumain
S
Jubault
P
Feasson
C
Quirion
JC