Synthetic melanocortin receptor agonists and antagonists.
Multiple melanocortin receptor subtypes with distinct cell and tissue distribution patterns have recently been identified, thereby presenting numerous opportunities for biological investigation. Many of these studies could benefit from the availability of subtype selective or specific agonists and antagonists. The purpose of this report is to summarize the state of available melanocortin receptor agonists and antagonists.
Lerner
M R
MR
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas 75235, USA. mrlerner@aol.com
D000324:Adrenocorticotropic Hormone / Q000737:chemistry / Q000502:physiology; D000595:Amino Acid Sequence; D000818:Animals; D006801:Humans; D009074:Melanocyte-Stimulating Hormones / Q000737:chemistry / Q000502:physiology; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000737:chemistry / Q000494:pharmacology*; D010456:Peptides, Cyclic / Q000737:chemistry / Q000494:pharmacology; D044104:Receptor, Melanocortin, Type 3; D044105:Receptor, Melanocortin, Type 4; D018043:Receptors, Corticotropin / Q000819:agonists* / Q000037:antagonists & inhibitors*; D044101:Receptors, Melanocortin
D009842:Oligopeptides; D010456:Peptides, Cyclic; D044104:Receptor, Melanocortin, Type 3; D044105:Receptor, Melanocortin, Type 4; D018043:Receptors, Corticotropin; D044101:Receptors, Melanocortin; C086971:melanocortin 5 receptor; D000324:Adrenocorticotropic Hormone; D009074:Melanocyte-Stimulating Hormones