title: Novel one-step synthesis of thiazolo[3,2-b]1,2,4-triazoles.
abstract: [reaction: see text] Reactions of chalcones 3a-f with bis(1H-1,2,4-triazolyl) sulfoxide 4 formed the thiazolo[3,2-b]1,2,4-triazoles 5a-f, which resemble closely some previously prepared COX-2 inhibitors. The structure of 5a was confirmed by X-ray analysis.
authors.affiliation: Department of Chemistry, Center for Heterocyclic Compounds, University of Florida, Gainesville 32611-7200, USA. katritzky@chem.ufl.edu
authors.forename: A R
authors.initials: AR
authors.lastname: Katritzky
authors.forename: A
authors.initials: A
authors.lastname: Pastor
authors.forename: M
authors.initials: M
authors.lastname: Voronkov
authors.forename: P J
authors.initials: PJ
authors.lastname: Steel
mesh_terms: D018360:Crystallography, X-Ray; D015394:Molecular Structure; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D014230:Triazoles