title: [Primary liposarcoma of the stomach wall--a rare mesenchymal tumor].
abstract: BACKGROUND
  Primary liposarcoma of the stomach wall is rare. Only eight cases have been described so far.
  
  
  METHODS
  Here we report the ninth case, occurring in a 74-year-old woman who presented with weight loss and a therapy-resistant ulcer of the stomach wall.
  
  
  RESULTS
  Pre- and perioperative findings suggested a benign lipoma of the stomach wall. The patient was treated with subtotal gastrectomy. On microscopic examination the tumor showed features of a benign lipoma but for a distinctive capillary net. Immunohistochemically the S-100 reaction was positive. Less than 1% of Ki67-positive cells could be found, thus suggesting a highly differentiated primary liposarcoma of the stomach wall.
  
  
  CONCLUSIONS
  In situations where the benign or malignant nature of a submucosal lesion cannot be diagnosed with certainty a mesenchymal tumor of the stomach wall has to be included in the differential diagnosis. Here the indication for complete surgical excision and histological workup has to be set widely.
authors.affiliation: Chirurgische Universitätsklinik und Poliklinik, RWTH Aachen.
authors.forename: B
authors.initials: B
authors.lastname: Philipps
authors.forename: M
authors.initials: M
authors.lastname: Lörken
authors.forename: E
authors.initials: E
authors.lastname: Manegold
authors.forename: R
authors.initials: R
authors.lastname: Kasperk
authors.forename: V
authors.initials: V
authors.lastname: Schumpelick
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D005743:Gastrectomy; D006801:Humans; D019394:Ki-67 Antigen / Q000032:analysis; D008080:Liposarcoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D009418:S100 Proteins / Q000032:analysis; D013270:Stomach / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*
chemical_list: D014408:Biomarkers, Tumor; D019394:Ki-67 Antigen; D009418:S100 Proteins