title: [Autoimmune hepatitis associated with thyroiditis and hypophysitis. A case report].
abstract: Autoimmune hepatitis primarily affects women and 40% of cases are associated with extrahepatic autoimmune dysfunction. Thyroiditis, ulcerative colitis and rheumatoid arthritis are the most commonly implicated entities. We present a 46-year-old woman with type-II autoimmune hepatitis and Graves disease who presented deterioration in level of consciousness, her symptoms mimicking severe liver failure. Hormone studies and nuclear magnetic resonance imaging revealed hypophysitis, which led to hypothyroidism and metabolic encephalopathy. The syndrome was resolved with hormone replacement therapy.
authors.affiliation: Servicio de Hepatología, Hospital Clínic, Barcelona.
authors.forename: V
authors.initials: V
authors.lastname: Piñol
authors.forename: J
authors.initials: J
authors.lastname: Cubiella
authors.forename: M
authors.initials: M
authors.lastname: Navasa
authors.forename: J
authors.initials: J
authors.lastname: Fernández
authors.forename: I
authors.initials: I
authors.lastname: Halperin
authors.forename: M
authors.initials: M
authors.lastname: Bruguera
authors.forename: J
authors.initials: J
authors.lastname: Rodés
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006111:Graves Disease / Q000175:diagnosis; D019693:Hepatitis, Autoimmune / Q000175:diagnosis*; D006801:Humans; D007037:Hypothyroidism / Q000175:diagnosis; D007249:Inflammation / Q000175:diagnosis; D017114:Liver Failure, Acute / Q000175:diagnosis; D008875:Middle Aged; D010900:Pituitary Diseases / Q000175:diagnosis*; D013966:Thyroiditis / Q000175:diagnosis*