A new complex of palladium-thiourea and carbon tetrabromide catalyzed carbonylative annulation of o-hydroxylarylacetylenes: efficient new synthetic technology for the synthesis of 2,3-disubstituted benzo[b]furans.
[reaction: see text] A highly effective cocatalysis system (PdI2-thiourea and CBr4) was developed for carbonylative cyclization of both electron-rich and electron-deficient o-hydroxylarylacetylenes to the corresponding methyl benzo[b]furan-3-carboxylates.
Nan
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Y
Harvard Institute of Chemistry and Cell Biology, Harvard University, Boston, Massachusetts 02115-5731, USA.
Miao
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H
Yang
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Z
D000596:Amino Acids / Q000138:chemical synthesis / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D006841:Hydrocarbons, Aromatic / Q000737:chemistry; D011108:Polymers / Q000138:chemical synthesis
D000596:Amino Acids; D006841:Hydrocarbons, Aromatic; D011108:Polymers