Urinary tract abnormalities in children with acute focal bacterial nephritis.
OBJECTIVE
To review the presentation, methods of diagnosis, and incidence of concomitant urological abnormalities in children with acute focal bacterial nephritis (AFBN, also known as lobar nephronia, a severe nonliquefactive infection involving one or more renal lobules).


METHODS
Sixteen children (age range 6 months to 9 years) diagnosed with AFBN over a 5-year period were retrospectively reviewed. Their age, gender, presenting symptoms, presence of urinary tract abnormalities, radiological imaging and treatment were assessed.


RESULTS
All 16 children received intensive intravenous and oral antibiotics. Ten required intervention for predisposing conditions including vesico-ureteric reflux (four), bladder diverticulum (one), renal and peri-rectal abscess (two), ureteric or bladder calculi (two), and renal mass (one). In addition, three children had reflux not requiring surgery; one had multiple renal calyceal diverticula, one had Hinman syndrome and one had leukaemia.


CONCLUSIONS
Acute focal bacterial nephritis is being diagnosed with increasing frequency through increasing awareness and advances in imaging modalities. Active urological evaluation is warranted because of the high incidence of urinary tract abnormalities. In addition to antibiotics, intervention was needed in most children in this series.
Uehling
D T
DT
Departments of Surgery (Urology) and Radiology, University of Wisconsin, Madison, Wisconsin 53792, USA.
Hahnfeld
L E
LE
Scanlan
K A
KA
D000208:Acute Disease; D001424:Bacterial Infections / Q000150:complications* / Q000175:diagnosis; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009393:Nephritis / Q000175:diagnosis / Q000209:etiology*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014552:Urinary Tract Infections / Q000150:complications* / Q000175:diagnosis