title: Hypothermic circulatory arrest in octogenarians: risk of stroke and mortality.
abstract: BACKGROUND
  The proportion of patients in their ninth decade of life undergoing complex cardiovascular procedures has increased over the past decade. The purpose of this study is to quantify the potential for stroke and mortality associated with deep hypothermic circulatory arrest (DHCA) in this age group.
  
  
  METHODS
  At our institution, 251 adult patients had cardiovascular procedures that required DHCA since 1989. This included 20 patients 80 years of age or older (group I) and 231 patients less than 80 years (group II). Additionally, we analyzed 632 patients 80 years of age or older who underwent a variety of cardiovascular procedures since 1989 that required cardiopulmonary bypass but not DHCA (group III). Neurologic outcomes have been maintained in our database prospectively since 1991.
  
  
  RESULTS
  The 30-day mortality in group I was 5%, in group II 15.2%, and in group III 8.2%. The stroke rate was 20% in group I, 8.8% in group II, and 6.5% in group III.
  
  
  CONCLUSIONS
  DHCA can be performed with acceptable early mortality in patients in their ninth decade of life, but they are at an increased risk of stroke. Follow-up shows satisfactory late survival.
authors.affiliation: Division of Cardiac Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Liddicoat
authors.forename: J M
authors.initials: JM
authors.lastname: Redmond
authors.forename: C M
authors.initials: CM
authors.lastname: Vassileva
authors.forename: W A
authors.initials: WA
authors.lastname: Baumgartner
authors.forename: D E
authors.initials: DE
authors.lastname: Cameron
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006324:Heart Arrest, Induced / Q000009:adverse effects / Q000401:mortality; D006801:Humans; D007036:Hypothermia, Induced; D012189:Retrospective Studies; D020521:Stroke / Q000209:etiology*