title: Serologic detection of adenoviral hemorrhagic disease in black-tailed deer in California.
abstract: An enzyme-linked immunosorbent assay (ELISA) and a serum neutralization (SN) test were developed to measure serum antibodies against the adenovirus causing hemorrhagic disease in free-ranging and captive experimentally-infected black-tailed deer (Odocoilenus hemionus columbianus) in California (USA). There was a strong (rho = 0.874) and significant (P < 0.0001) correlation between ELISA and SN titers, although the SN assay was more sensitive than the ELISA.
authors.affiliation: Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California at Davis, 95616, USA. lapoije@medvet.umontreal.ca
authors.forename: J M
authors.initials: JM
authors.lastname: Lapointe
authors.forename: L W
authors.initials: LW
authors.lastname: Woods
authors.forename: H D
authors.initials: HD
authors.lastname: Lehmkuhl
authors.forename: M K
authors.initials: MK
authors.lastname: Keel
authors.forename: P V
authors.initials: PV
authors.lastname: Rossitto
authors.forename: P K
authors.initials: PK
authors.lastname: Swift
authors.forename: N J
authors.initials: NJ
authors.lastname: MacLachlan
mesh_terms: D000257:Adenoviridae Infections / Q000175:diagnosis / Q000276:immunology / Q000662:veterinary*; D000818:Animals; D000835:Animals, Wild; D000836:Animals, Zoo; D000914:Antibodies, Viral / Q000097:blood*; D002140:California; D003670:Deer; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D006470:Hemorrhage / Q000175:diagnosis / Q000276:immunology / Q000662:veterinary* / Q000821:virology; D017921:Mastadenovirus / Q000276:immunology*; D009500:Neutralization Tests / Q000662:veterinary; D011817:Rabbits
chemical_list: D000914:Antibodies, Viral