[Tanfelam: synthesis, study of ovicidal activity, and acute toxicity].
The papers describes the synthesis of N-(2-piperidinoethyl)-N-tosyl-n-anisidine (Tanfelam) which showed a 100% ovicidal activity when tested by the Harada and Mori methods (in vitro inhibited N.brasiliensis hatching and development test). Tanfelam has been transferred for in-depth tests.
Mikhaĭlitsyn
F S
FS
Fedianina
L V
LV
Bolotina
L A
LA
Lebedeva
M N
MN
Lychko
N D
ND
D000818:Animals; D021461:Animals, Outbred Strains; D004305:Dose-Response Relationship, Drug; D005260:Female; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D008018:Life Cycle Stages / Q000187:drug effects*; D008297:Male; D051379:Mice; D015394:Molecular Structure; D009559:Nippostrongylus / Q000187:drug effects / Q000254:growth & development*; D010063:Ovum / Q000187:drug effects*; D010880:Piperidines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D013997:Time Factors; D014105:Tosyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D023382:Toxicity Tests, Acute
D010880:Piperidines; D014105:Tosyl Compounds; C408627:tanfelam