title: [Interference by D-mannitol on serum D-arabinitol determination by enzymatic assay].
abstract: We examined a disparity in D-arabinitol values between two commercial assay kits, LABOFIT and ARABINITEC-AUTO. The determined values by the former were increased by 26%(y = 0.2643x) because of concomitant D-mannitol, whereas those by our newly developed ARABINITEC-AUTO was increased only by 2%(y = 0.0242x). Of 109 samples, 5 samples were found to contain more than 100 mumol/l of D-mannitol. A clear relation(r = 0.89) was noted between the degree of disparity between measurements by the two methods and D-mannitol concentrations in samples. Thus, we have proved that the disparity is mainly caused by D-mannitol.
authors.affiliation: Marukin Shoyu Co., Ltd., Kyoto.
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuda
authors.forename: Y
authors.initials: Y
authors.lastname: Ohta
authors.forename: Y
authors.initials: Y
authors.lastname: Tsukada
authors.forename: H
authors.initials: H
authors.lastname: Nishikiori
authors.forename: T
authors.initials: T
authors.lastname: Sakai
authors.forename: S
authors.initials: S
authors.lastname: Yuasa
authors.forename: N
authors.initials: N
authors.lastname: Fujita
authors.forename: M
authors.initials: M
authors.lastname: Yoshimura
mesh_terms: D015415:Biomarkers / Q000097:blood; D002177:Candidiasis / Q000175:diagnosis; D006801:Humans; D008353:Mannitol; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D013053:Spectrophotometry / Q000379:methods; D013402:Sugar Alcohols / Q000097:blood*
chemical_list: D015415:Biomarkers; D011933:Reagent Kits, Diagnostic; D013402:Sugar Alcohols; D008353:Mannitol; C014999:arabitol