title: Steatocystoma multiplex suppurativum: oral isotretinoin treatment combined with cryotherapy.
abstract: A 30-year-old man presented with numerous papules, nodules and inflamed cysts. The lesions were located all over the body, including the scalp, except the palms and soles. His mother and one sister had had similar but less extensive lesions. Histopathology of the biopsy specimens obtained from the anterior chest wall, axillae and the back region was consistent with steatocystoma multiplex (SM). A diagnosis of steatocystoma multiplex suppurativum was made. The inflamed lesions were treated with oral isotretinoin (1 mg/kg per daily) for 6 months. At the same time, cryotherapy was used for non-suppurating lesions smaller than 2 cm. When the patient was evaluated 6 months later, cosmetic results were good. No new lesions have appeared in the subsequent 12-month follow up.
authors.affiliation: Department of Dermatology, School of Medicine, University of Kocaeli, Izmit, Turkey.
authors.forename: R
authors.initials: R
authors.lastname: Apaydin
authors.forename: N
authors.initials: N
authors.lastname: Bilen
authors.forename: D
authors.initials: D
authors.lastname: Bayramgürler
authors.forename: F
authors.initials: F
authors.lastname: Başdaş
authors.forename: G
authors.initials: G
authors.lastname: Harova
authors.forename: S
authors.initials: S
authors.lastname: Dökmeci
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001706:Biopsy; D003131:Combined Modality Therapy; D017679:Cryotherapy; D003560:Cysts / Q000188:drug therapy* / Q000235:genetics; D004954:Esthetics; D005500:Follow-Up Studies; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage / Q000627:therapeutic use*; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D017444:Skin Diseases, Papulosquamous / Q000188:drug therapy* / Q000235:genetics; D013492:Suppuration
chemical_list: D007641:Keratolytic Agents; D015474:Isotretinoin