Metabolic complications of obesity. Pathophysiologic considerations.
Given a specific research interest in human fatty acid metabolism, this article focuses primarily on the evidence surrounding the hypothesis that dysregulation of the fuel release function of fat cells (lipolysis) is an important contributing factor to the health hazards of obesity.
Sheehan
M T
MT
Endocrine Research Unit, Mayo Clinic, Rochester, Minnesota, USA.
Jensen
M D
MD
D000273:Adipose Tissue / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D005227:Fatty Acids / Q000378:metabolism; D006801:Humans; D006949:Hyperlipidemias / Q000503:physiopathology; D006973:Hypertension / Q000503:physiopathology; D007333:Insulin Resistance / Q000502:physiology*; D008066:Lipolysis / Q000502:physiology*; D009765:Obesity / Q000150:complications / Q000503:physiopathology*; D013577:Syndrome
D005227:Fatty Acids