[The synthesis of galactopyranosyl-substituted derivatives of pheophorbide].
New pheophorbide and pyropheophorbide derivatives containing carbohydrate fragments, derivatives of galactopyranose, were synthesized. Galactopyranosylpheophorbide and galactopyranosylpyropheophorbide with free hydroxyl groups were found to be water-soluble and useful as sensitizers in photodynamic therapy of cancer.
Aksenova
A A
AA
Lomonosov State Academy of Fine Chemical Technology, Moscow, Russia.
Sebiakin
Iu L
IuL
Mironov
A F
AF
D002734:Chlorophyll / Q000138:chemical synthesis* / Q000737:chemistry*; D005690:Galactose; D017319:Photosensitizing Agents / Q000138:chemical synthesis / Q000737:chemistry; D011166:Porphyrins / Q000138:chemical synthesis* / Q000737:chemistry*
D017319:Photosensitizing Agents; D011166:Porphyrins; D002734:Chlorophyll; D005690:Galactose