Failure of azithromycin in treatment of Brill-Zinsser disease.
Two patients suffering from Brill-Zinsser disease were treated with azithromycin, which did not prove effective. Rickettsia prowazekii, the agent causing Brill-Zinsser disease, cannot be treated with azithromycin. Both patients had epidemiological features consistent with and a clinical course typical of the disease. The diagnosis of Brill-Zinsser disease was serologically confirmed.
Turcinov
D
D
University Hospital for Infectious Diseases, Zagreb, Croatia. dturcinov@bfm.hr
Kuzman
I
I
Herendić
B
B
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012283:Rickettsia prowazekii / Q000187:drug effects*; D017211:Treatment Failure; D014438:Typhus, Epidemic Louse-Borne / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D017963:Azithromycin