[Acquired ocular toxoplasmosis (panuveitis) after liver transplantation].
We present one case of acquired Toxoplasma gondii retinochoroiditis after livrer transplantation. Three weeks after receiving liver transplant from a seropositive donor for Toxoplasma gondii, the fundus examination showed a vitreal haze and an edematous retinal lesion with retinal hemorrhages. Routine screening tests for uveitis were performed. The serum toxoplasmosis titers revealed a seroconversion for toxoplasmosis (pre-transplantation tests were negative). The PCR assay on aqueous humor resulted in an amplified product identical to toxoplasmosis. This immunocompromised patient likely received an infected hepatic transplant. The patient's ocular inflammation cleared on 1-month pyrimethamine-sulfadiazine medication. Four months later, the patient developed a retinal detachment with massive proliferative vitreoretinopathy.
Chiquet
C
C
Service d'Ophtalmologie, Hôpital de la Croix-Rousse, Lyon, France.
Fleury
J
J
Blanc-Jouvan
M
M
Wallon
M
M
Boibieux
A
A
D000328:Adult; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D016031:Liver Transplantation; D011183:Postoperative Complications; D011739:Pyrimethamine / Q000627:therapeutic use; D013411:Sulfadiazine / Q000627:therapeutic use; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission*; D014605:Uveitis / Q000175:diagnosis / Q000209:etiology*
D000981:Antiprotozoal Agents; D013411:Sulfadiazine; D011739:Pyrimethamine