[Multiple primaries of the upper aerodigestive tract, esophagus, and lung].
The existence of multiple primary tumors of the upper aerodigestive tract, esophagus, and lung (UADT-E-L) is related with a common etiopathogenic factor (alcohol-tobacco association). In a review of 43 patients, 6.75% with a UADT-E-L tumor developed another neoplasm, 3.25% at the same site. Nine percent (8.59%) of the tumors were synchronic and 10.85% were metachronic. The most frequent association was larynx-lung. Another neoplasm was detected by physical examination and/or radiology in 44.18% of cases, with a time lapse of less than 3 years in 50%. The most frequent treatment was surgery with/without complementary radiotherapy. The most common stage was T1-T2 (62.06%) and N0-N1 (68.96%). The survival rate was 31% at 2 years and 25% at 3 years.
García Cantos
M
M
Servicio de ORL, Hospital Universitario Puerta del Mar, Cádiz, España.
De Mier Morales
M
M
Delgado Balufo
D
D
Márquez García-Salazar
M M
MM
Jaén Olazolo
J
J
Porras Alonso
E
E
Carrillo de Albornoz y Vargas
F
F
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000453:epidemiology*; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology; D004938:Esophageal Neoplasms / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000453:epidemiology*; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology*; D010039:Otorhinolaryngologic Neoplasms / Q000453:epidemiology*