title: Growth of the fungal pathogen Candida in parotid saliva of patients with burning mouth syndrome.
abstract: Subclinical Candida infection has been suggested as one of the aetiological factors in patients with burning mouth syndrome (BMS). In order to investigate the possible factors which contribute to the relatively high isolation rate of Candida in BMS, parotid saliva samples (20 in toto) from patients with this condition were collected and the growth of Candida in each sample dynamically observed using a computerized turbidometric assay system. A total of thirteen parotid saliva samples obtained from healthy individuals served as normal controls. The results showed no significant growth differential within the test and control saliva samples, when a single isolate each of Candida albicans and Candida tropicalis were cultured for 24 h, at 37 degrees C. A single isolate of Candida glabrata tended to grow better in the saliva from BMS patients than the controls. These results indicate that the composition of saliva may be a contributory factor for the high isolation rate of Candida in saliva of BMS patients.
authors.affiliation: Oral Bio-Sciences, Faculty of Dentistry, The University of Hong Kong.
authors.forename: Q
authors.initials: Q
authors.lastname: Chen
authors.forename: L P
authors.initials: LP
authors.lastname: Samaranayake
mesh_terms: D000328:Adult; D002054:Burning Mouth Syndrome / Q000382:microbiology*; D002175:Candida / Q000235:genetics / Q000254:growth & development*; D005260:Female; D006801:Humans; D008297:Male; D010306:Parotid Gland / Q000378:metabolism; D012463:Saliva / Q000737:chemistry / Q000382:microbiology*