Tandem oxy-Cope/transannular ene reaction of 1,2-divinylcyclohexanols
[reaction: see text] The syntheses via tandem oxy-Cope/transannular ene reaction of 1,2-divinylcyclohexanols to bi- and tricyclic skeletons are described. This strategy generates a rapid method for the preparation of advanced polycyclic intermediates with high diastereoselectivity.
Warrington
JM
Department of Chemistry, University of Ottawa, Ontario, Canada.
Yap
GP
Barriault
L