[Functional condition of pancreas after stomach resection according to Roux].
Available are the results of surgical treatment of 90 patients with stenotic gastroduodenal ulcer in Burdenko Surgical Faculty Hospital of Sechenov Moscow Medical Academy between 1984 and 1985. 30 patients (study group) underwent stomach Roux-type resection. Truncal vagotomy with a stomach Bilroth-I resection was made in 20 control patients, after 20 control patients had a truncal vagotomy with pyloroplasty according to Heineke-Mikulicz, and 20 patients had selective proximal vagotomy with gastroduodenostomy by Joboulay (the third control group). Exocrine function of the pancreas was assessed by serum concentration of immunoreactive trypsin, endocrine function by fasting blood sugar, oral glucose tolerance and serum concentration of immunoreactive insulin. The authors came to the conclusion that exocrine function of the pancreas was equally damaged in patients with a Roux stomach resection, stem vagotomy with a stomach Bilroth-I resection and a stem vagotomy with pyloroplasty Heineke-Mikulicz. After selective proximal vagotomy a level of immunoreactive trypsin was normal. After a Roux stomach resection relative incompetence of basophil cells of the pancreas and long increase of insulin in the blood were observed but without influence on the glucose curve. The changes of glucose curve and level of immunoreactive insulin were similar in the control groups.
Kuzin
N M
NM
Kanadashvili
O V
OV
Maĭorova
E M
EM
D000713:Anastomosis, Roux-en-Y; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D004386:Duodenum / Q000601:surgery*; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000502:physiology*; D011184:Postoperative Period; D013270:Stomach / Q000601:surgery*; D013276:Stomach Ulcer / Q000601:surgery*; D014357:Trypsin / Q000097:blood; D014628:Vagotomy / Q000379:methods
D015415:Biomarkers; D001786:Blood Glucose; D007328:Insulin; D014357:Trypsin