Systemic lupus erythematosus presenting as mania.
OBJECTIVE
Psychiatric manifestations of systemic lupus erythematosus (SLE) are well recognized but usually occur in the later stages of the illness, with organic syndromes being the most common. This case highlights the fact that SLE can present with mania.


METHODS
Single case report.


RESULTS
A 32-year-old woman was admitted to hospital with her first manic illness. Physical examination and investigations revealed her to be suffering from SLE although this had not been previously diagnosed. Her physical and psychiatric symptoms settled rapidly following treatment with prednisolone and chlorpromazine.


CONCLUSIONS
The case emphasizes the polymorphous manifestations of SLE and the importance of considering physical disorders in patients with a first episode of psychosis.
Khan
S
S
Trafford General Hospital, Davyhulme, Manchester, UK.
Haddad
P
P
Montague
L
L
Summerton
C
C
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000974:Antibodies, Antinuclear / Q000097:blood; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000188:drug therapy; D002746:Chlorpromazine / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D011239:Prednisolone / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D000974:Antibodies, Antinuclear; D014150:Antipsychotic Agents; D011239:Prednisolone; D002746:Chlorpromazine