title: Prognostic significance of antisocial personality disorder in cocaine-dependent patients entering continuing care.
abstract: This study examined the relationship of antisocial personality disorder (APD) to response to continuing care treatments in a sample of cocaine-dependent patients. Patients (N = 127) were randomly assigned to 20-week standard group or individualized relapse prevention continuing care interventions after the completion of an initial treatment episode and followed up at 3, 6, and 12 months. APD and non-APD patients did not differ on retention in continuing care, substance use outcomes, social function outcomes, or experiences before or during cocaine relapse episodes. A diagnosis of APD was also not a predictor of differential response to the two continuing care interventions in the study. However, APD patients had worse medical and psychiatric problem severity than non-APD patients at entrance to continuing care and during follow-up. These results suggest that cocaine patients with APD who are in the continuing care phase of outpatient rehabilitation might benefit from additional medical and psychiatric treatment services.
authors.affiliation: Department of Psychiatry, University of Pennsylvania, Philadelphia, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: McKay
authors.forename: A I
authors.initials: AI
authors.lastname: Alterman
authors.forename: J S
authors.initials: JS
authors.lastname: Cacciola
authors.forename: F D
authors.initials: FD
authors.lastname: Mulvaney
authors.forename: C P
authors.initials: CP
authors.lastname: O'Brien
mesh_terms: D000359:Aftercare / Q000379:methods; D000987:Antisocial Personality Disorder / Q000175:diagnosis* / Q000453:epidemiology; D019970:Cocaine-Related Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000534:rehabilitation*; D015897:Comorbidity; D003266:Continuity of Patient Care; D003866:Depressive Disorder / Q000453:epidemiology / Q000523:psychology; D005500:Follow-Up Studies; D006801:Humans; D010349:Patient Compliance; D011379:Prognosis; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011615:Psychotherapy, Group / Q000379:methods; D055502:Secondary Prevention; D012720:Severity of Illness Index; D015813:Substance Abuse Detection; D016896:Treatment Outcome