title: Total synthesis of (+/-)-isoschizogamine.
abstract: [formula: see text] Isoschizogamine has been prepared for the first time. The synthesis requires eight steps from a readily available ketone starting material and features an aminal-forming cyclization that is based on a proposed biosynthetic transformation.
authors.affiliation: Department of Chemistry, University of California, Berkeley 94720, USA.
authors.forename: J L
authors.initials: JL
authors.lastname: Hubbs
authors.forename: C H
authors.initials: CH
authors.lastname: Heathcock
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D026121:Indole Alkaloids; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000470:Alkaloids; D026121:Indole Alkaloids; D007211:Indoles; C409122:isoschizogamine