title: Synthesis of 2-substituted-2,3- dihydro-1,4-dioxino[2,3-b]pyridine derivatives.
abstract: [reaction--see text] A variety of 2-substituted-2,3-dihydro-1,4-dioxino[2,3-b]pyridines B have been synthesized from the readily available 2-nitro-3-oxiranylmethoxypyridine 1 via a Smiles rearrangement. We demonstrate how variations of reaction conditions affect the product distribution of A and B.
authors.affiliation: Institut de Chimie Organique et Analytique associé au CNRS, Université d'Orléans, BP 6759, 45067 Orléans Cedex 2, France.
authors.forename: M
authors.initials: M
authors.lastname: Soukri
authors.forename: S
authors.initials: S
authors.lastname: Lazar
authors.forename: M
authors.initials: M
authors.lastname: Akssira
authors.forename: G
authors.initials: G
authors.lastname: Guillaumet
mesh_terms: D004147:Dioxins / Q000138:chemical synthesis* / Q000737:chemistry; D015195:Drug Design; D009682:Magnetic Resonance Spectroscopy; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D004147:Dioxins; D011725:Pyridines