title: Perforin: more than just an effector molecule.
authors.affiliation: Graduate Program in Immunology, University of Texas Southwestern Medical School, Dallas, TX 75235, USA.
authors.forename: S E
authors.initials: SE
authors.lastname: Stepp
authors.forename: P A
authors.initials: PA
authors.lastname: Mathew
authors.forename: M
authors.initials: M
authors.lastname: Bennett
authors.forename: G
authors.initials: G
authors.lastname: de Saint Basile
authors.forename: V
authors.initials: V
authors.lastname: Kumar
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000235:genetics / Q000276:immunology; D015551:Autoimmunity; D002675:Child, Preschool; D002879:Chromosomes, Human, Pair 10 / Q000235:genetics; D003594:Cytoplasmic Granules / Q000378:metabolism; D003602:Cytotoxicity, Immunologic; D053222:Fas Ligand Protein; D005246:Feedback; D015616:Histiocytosis, Non-Langerhans-Cell / Q000235:genetics; D006801:Humans; D007223:Infant; D007694:Killer Cells, Natural / Q000276:immunology; D008213:Lymphocyte Activation; D008216:Lymphocytic Choriomeningitis / Q000276:immunology; D008217:Lymphocytic choriomeningitis virus / Q000502:physiology; D008232:Lymphoproliferative Disorders / Q000235:genetics / Q000276:immunology; D008562:Membrane Glycoproteins / Q000172:deficiency / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D051379:Mice; D008810:Mice, Inbred C57BL; D019463:Mice, Inbred MRL lpr; D018345:Mice, Knockout; D054353:Perforin; D052899:Pore Forming Cytotoxic Proteins; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D017735:Virus Latency
chemical_list: C505661:FASLG protein, human; D053222:Fas Ligand Protein; C505658:Fasl protein, mouse; D008562:Membrane Glycoproteins; D052899:Pore Forming Cytotoxic Proteins; D054353:Perforin