title: [The clinical monitoring of epileptic seizures].
abstract: The Chalfont Scale of Cerebral Seizure Severity has been adapted for use in a computer case history and the making-decision support system in managing patients with cerebral seizures (CS). The index of severity of cerebral seizures (CSSI) has been worked out, it being taken as the sum of results of assessment of the same type CS according to the Chalfont Scale of Cerebral Seizure Severity multiplied by the frequency of the paroxysms for all types of fits occurring in the given patient. The frequency of the same type CS is an arbitrary value for the number of such fits occurring during the 24-hour period, it can be a fractional number. This value is calculated on the basis of a more prolonged period out of the following two time periods: time between the last two CS or time between the last seizure and the moment of the computations made. Using the above-described approach a physician or the particular information system can speedily assess an individual course of the malady and efficacy of the treatment option chosen. The graphic representation of SSI and of doses of antiepileptic drugs stated in terms of phenobarbital units helps in creating an integral idea of a particular case. The assessment by the information system of the time-related clinical course of the disease in 30 CS patients with making use of CSSI was found out to be in full agreement with opinions of three experts. Based on the use of CSSI in a clinical monitoring of CS in 111 patients there has been determined a place for the above index among other characteristics of the illness with preliminary recommendations having been given on its interpretation and role in managing of CS patients.
authors.forename: O V
authors.initials: OV
authors.lastname: Kurliandchykov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use; D016009:Chi-Square Distribution; D016000:Cluster Analysis; D003936:Diagnosis, Computer-Assisted / Q000706:statistics & numerical data; D004827:Epilepsy / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000706:statistics & numerical data; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D013997:Time Factors
chemical_list: D000927:Anticonvulsants