A case of viral warts with particular fibrillar intracytoplasmic inclusion bodies.
A new type of skin wart was observed in a Japanese patient. It was characterized by intracytoplasmic inclusions with a 'fibrillar' structure which were distinct from previously described wart-associated inclusions. The papillomavirus (HPV)-group-specific antigen could be detected, but DNA hybridization and PCR amplification using probes or PCR primers specific for the main skin HPV genotypes (including HPV-63 which is also associated with 'filamentous' inclusions) were negative. We consider that this cytopathic effect could correspond to an HPV genotype which has not yet been characterized.
Egawa
K
K
Department of Dermatology, Kumamoto University School of Medicine, Kumamoto, Japan. kuroibo@kaiju.medic.kumamoto-u.ac.jp
Honda
Y
Y
Ono
T
T
Kitasato
H
H
D000328:Adult; D000956:Antigens, Viral / Q000032:analysis; D005838:Genotype; D006801:Humans; D007181:Inclusion Bodies, Viral / Q000473:pathology*; D008297:Male; D008969:Molecular Sequence Data; D027383:Papillomaviridae / Q000235:genetics / Q000276:immunology; D017193:Skin Diseases, Viral / Q000473:pathology*; D014860:Warts / Q000473:pathology* / Q000821:virology
D000956:Antigens, Viral