title: Aluminum phosphide fatalities, new local experience.
abstract: Aluminum phosphide (AlP) pesticide is a highly toxic, low cost, and easily accessible rodenticidal agent. Its toxicity results from the liberation of phosphine gas upon exposure to moisture, which leads to multisystem involvement, resulting in serious consequences. The highly toxic parathion insecticide was a common cause of mortality in pesticide fatalities, prior to its banning. Its toxicity was familiar to the public as well as to physicians. Recently, ten fatalities due to AlP were encountered within a three-month period during spring, when it was used as a rodenticide in the vicinity of grain stores. The victims' ages ranged from 1-34 years. The circumstances of death were accidental in six cases, suicidal in two and possibly homicidal in two cases. Retrospectively, the clinical manifestations, scene investigation, autopsy, histological and toxicological findings supported the diagnosis of AlP intoxication. Immediate recognition was difficult due to unfamiliarity of the agent to the physicians. The occurrence of these fatalities might suggest changes of pattern in pesticide poisoning. This should raise the attention of the physician to the problem of AlP poisoning and also necessitates the awareness of the public to the hazards of this poison. Education, proper handling, strict observation and abiding by the regulations controlling this material are good protective measures against AlP poisoning.
authors.affiliation: Faculty of Medicine, University of Jordan, Amman, Jordan.
authors.forename: H A
authors.initials: HA
authors.lastname: Abder-Rahman
authors.forename: A H
authors.initials: AH
authors.lastname: Battah
authors.forename: Y M
authors.initials: YM
authors.lastname: Ibraheem
authors.forename: M S
authors.initials: MS
authors.lastname: Shomaf
authors.forename: N
authors.initials: N
authors.lastname: el-Batainch
mesh_terms: D000293:Adolescent; D000328:Adult; D017607:Aluminum Compounds / Q000506:poisoning*; D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D007597:Jordan / Q000453:epidemiology; D008297:Male; D010575:Pesticides / Q000506:poisoning*; D010720:Phosphines / Q000506:poisoning*; D011041:Poisoning / Q000401:mortality / Q000473:pathology / Q000517:prevention & control
chemical_list: D017607:Aluminum Compounds; D010575:Pesticides; D010720:Phosphines; C001864:aluminum phosphide