title: A practical technique for verification of three-dimensional conformal dose distributions in stereotactic radiosurgery.
abstract: The trend toward conformal techniques in stereotactic radiosurgery necessitates an accurate and practical method for verification of irregular three-dimensional dose distributions. This work presents the design and evaluation of a phantom system facilitating the measurement of conformal dose distributions using one or more arrays of up to 20 radiographic films separated by 3.2 mm-thick tissue-equivalent spacers. Using Electron Gamma Shower version 4 (EGS4) Monte Carlo simulation, we show that for 6 MV radiosurgical photon beams this arrangement preserves tissue-equivalence to within 1%. The phantom provides 0.25 mm in-plane spatial resolution and multiple sets of films may be used to resample the dose volume in orthogonal planes. Dedicated software has been developed to automate the process of ordering and orienting of scanned film images, conversion of scanned pixel value to dose, resampling of one or more sets of film images and subsequent export of images in DICOM format for coregistration of planned and measured dose volumes. Calculated and measured isodose surfaces for a simple, circular-beam treatment agree to within 1.5 mm throughout the dose volume. For conformal radiosurgical applications, the measured and planned dose distributions agree to within the uncertainty of the manufacture of irregularly shaped collimators. The sensitivity of this technique to minor spatial inaccuracies in beam shaping is also demonstrated.
authors.affiliation: The University of British Columbia, Department of Physics, BC Cancer Agency, Vancouver, Canada. jrobar@bccancer.bc.ca
authors.forename: J L
authors.initials: JL
authors.lastname: Robar
authors.forename: B G
authors.initials: BG
authors.lastname: Clark
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D001932:Brain Neoplasms / Q000532:radiotherapy; D004583:Electrons; D006801:Humans; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D017785:Photons; D016634:Radiosurgery / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D020266:Radiotherapy, Conformal / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D011882:Radiotherapy, High-Energy / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D012984:Software; D014962:X-Ray Film