[Retinal vein occlusions: diseases for the internist?].
Retinal vein occlusion is a relatively common disease, usually associated with the presence of diseases related to internal medicine. Central retinal vein occlusion is the most frequently-occurring and clinically relevant type. In addition to the well-known classic risk factors, new hemostasis-related ones have been investigated in patients affected by central retinal vein occlusion. While data concerning a number of parameters remain contradictory, high levels of type 1 plasminogen activator inhibitor (PAI-1) and lipoprotein(a) and hyper-homocystinemia appear to play a significant role in the pathogenesis of this disease. Although based on a limited number of studies, this new knowledge could eventually provide important indications regarding prognosis and therapeutic strategies.
Prisco
D
D
Centro di Riferimento Regionale per la Trombosi, Università degli Studi, Azienda Ospedaliera Careggi di Firenze. d.prisco@dfc.unifi.it
Bertini
L
L
Marcucci
R
R
Poli
D
D
D006487:Hemostasis; D006801:Humans; D007388:Internal Medicine; D012169:Retinal Vein / Q000473:pathology; D012170:Retinal Vein Occlusion / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000628:therapy; D012307:Risk Factors