Indicanines B and C, two isoflavonoid derivatives from the root bark of Erythrina indica.
In addition to two known compounds, 5,4'-di-O-methylalpinumisoflavone and cajanin, a new 3-phenylcoumarin metabolite, named indicanine B, and a new isoflavone derivative, named indicanine C, were isolated from the root bark of Erythrina indica. By means of spectroscopic analysis, the structures of the new compounds were characterized as 4-hydroxy-3-(4'-hydroxyphenyl)-5-methoxy-2",2"-dimethylpyrano [5",6":6,7] coumarin and 4'-hydroxy-5-methoxy-2",2"-dimethylpyrano [5",6":6,7] isoflavone, respectively. The 13C-NMR data of cajanin and the in vitro antimicrobial spectrum and potencies of the isolated compounds are also reported.
Waffo
A K
AK
Department of Organic Chemistry, University of Yaounde I, Cameroon.
Azebaze
G A
GA
Nkengfack
A E
AE
Fomum
Z T
ZT
Meyer
M
M
Bodo
B
B
van Heerden
F R
FR
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004895:Erythrina / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D009161:Mycobacterium / Q000187:drug effects; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D003374:Coumarins; D007529:Isoflavones; C412072:indicanine B; C412071:indicanine C