Genetic polymorphism of 4 STR loci on chromosome 17 in Chinese Han.
OBJECTIVE
To analyze genetic polymorphism of D17S1290, D17S1293, D17S1303 and D17S1308 in Chinese Hans.


METHODS
Fifty unrelated individuals were analyzed by PCR amplification fragment length polymorphism analysis method.


RESULTS
9, 7, 5, 5 alleles were observed at these 4 STR loci respectively, the genotypes distributions in Chinese Hans were in accordance with Hardy-Weinberg equilibrium, the expected heterozygosities for these loci were 0.770, 0.828, 0.608, 0.669 respectively, the polymorphism information contents(PIC) were 0.763, 0.820, 0.602, 0.662 respectively.


CONCLUSIONS
The results demonstrate these 4 STR loci can be used for genetic analysis.
Zou
Y
Y
Department of Medical Genetics, Shandong Medical University, Jinan, Shandong, 250012 P. R. China. Genet@public.jn.sd.cn
Guo
C
C
Liu
X
X
Chen
B
B
Lu
Y
Y
Gong
Y
Y
D002681:China / Q000208:ethnology; D002886:Chromosomes, Human, Pair 17; D005260:Female; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences