title: Zirconium-mediated asymmetric baeyer-villiger oxidation.
abstract: Combinations of axially chiral C2-symmetric diols were used as ligands in zirconium-mediated Baeyer-Villiger reactions. The in situ preformed Zr-diol species proved effective in the asymmetric oxidation of bicyclic and monosubstituted cyclobutanones when a hydroperoxide was employed as oxidant. Asymmetric induction could be preserved upon replacement of one out of two enantiopure BINOL ligands by conformationally flexible 2,2'-biphenol.
authors.affiliation: Institut fur Organische Chemie der RWTH Aachen, Aachen, Germany. Carsten.Bolm@oc.rwth-aachen.de
authors.forename: C
authors.initials: C
authors.lastname: Bolm
authors.forename: O
authors.initials: O
authors.lastname: Beckmann