Applications of aziridinium ions. Selective syntheses of beta-aryl-alpha,beta-diamino esters.
[formula: see text] alpha,beta-Diamino esters are readily prepared through stereospecific and regioselective opening of an aziridinium ion intermediate with a variety of amines. The aziridinium ion is generated from the epoxide in two steps.
Chuang
T H
TH
Department of Chemistry, Scripps Research Institute, La Jolla, California 92037, USA.
Sharpless
K B
KB
D000588:Amines / Q000737:chemistry; D001388:Aziridines / Q000737:chemistry*; D004952:Esters; D008958:Models, Molecular
D000588:Amines; D001388:Aziridines; D004952:Esters