title: Mycobacterium tuberculosis Beijing genotype emerging in Vietnam.
abstract: To assess whether the Mycobacterium tuberculosis Beijing genotype is emerging in Vietnam, we analyzed 563 isolates from new cases by spoligotyping and examined the association between the genotype and age, resistance, and BCG vaccination status. Three hundred one (54%) patients were infected with Beijing genotype strains. The genotype was associated with younger age (and hence with active transmission) and with isoniazid and streptomycin resistance, but not with BCG vaccination.
authors.affiliation: National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
authors.forename: D D
authors.initials: DD
authors.lastname: Anh
authors.forename: M W
authors.initials: MW
authors.lastname: Borgdorff
authors.forename: L N
authors.initials: LN
authors.lastname: Van
authors.forename: N T
authors.initials: NT
authors.lastname: Lan
authors.forename: T
authors.initials: T
authors.lastname: van Gorkom
authors.forename: K
authors.initials: K
authors.lastname: Kremer
authors.forename: D
authors.initials: D
authors.lastname: van Soolingen
mesh_terms: D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000494:pharmacology; D001500:BCG Vaccine; D004352:Drug Resistance, Microbial; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D009838:Oligodeoxyribonucleotides / Q000235:genetics; D016133:Polymerase Chain Reaction; D014376:Tuberculosis / Q000453:epidemiology* / Q000382:microbiology*; D014611:Vaccination; D014744:Vietnam / Q000453:epidemiology
chemical_list: D000995:Antitubercular Agents; D001500:BCG Vaccine; D009838:Oligodeoxyribonucleotides