title: Reduced cerebral embolic signals in beating heart coronary surgery detected by transcranial Doppler ultrasound.
abstract: Cerebral emboli detected by transcranial Doppler imaging were recorded in 20 patients undergoing multiple-vessel coronary artery bypass surgery, either with or without cardiopulmonary bypass, in a prospective unblinded comparative study. Emboli were recorded continuously from the time of pericardial incision until 10 min after the last aortic instrumentation. The numbers of coronary grafts and of aortic clampings were also documented. Patients undergoing revascularization with cardiopulmonary bypass had more emboli (median 79, range 38-876) per case compared with patients having off-pump surgery (median 3, range 0-18). No clinically detectable neurological deficits were seen in either group. Beating heart surgery is associated with fewer emboli than coronary surgery with cardiopulmonary bypass. Further research is necessary to determine whether a smaller number of emboli alters the incidence of neurological deficit after cardiac surgery.
authors.affiliation: Sir Humphry Davy Department of Anaesthesia, Bristol Royal Infirmary, UK.
authors.forename: M P
authors.initials: MP
authors.lastname: Watters
authors.forename: A M
authors.initials: AM
authors.lastname: Cohen
authors.forename: C R
authors.initials: CR
authors.lastname: Monk
authors.forename: G D
authors.initials: GD
authors.lastname: Angelini
authors.forename: I G
authors.initials: IG
authors.lastname: Ryder
mesh_terms: D000368:Aged; D002315:Cardiopulmonary Bypass / Q000009:adverse effects* / Q000379:methods; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D020766:Intracranial Embolism / Q000000981:diagnostic imaging* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D017585:Ultrasonography, Doppler, Transcranial