title: Principles of selection and use of antibacterial agents. In vitro activity and pharmacology.
abstract: The selection of an antimicrobial treatment regimen is based on many factors, including the nature of the infection, the identity and susceptibility pattern of the infecting organisms, and the pharmacokinetics and pharmacodynamics of the antibacterial drugs. This article discusses principles of susceptibility testing, pharmacology, and monitoring of therapy.
authors.affiliation: Department of Medicine, Medical College of Pennsylvania, Hahnemann School of Medicine, Philadelphia, USA.
authors.forename: M T
authors.initials: MT
authors.lastname: Hessen
authors.forename: D
authors.initials: D
authors.lastname: Kaye
mesh_terms: D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents