Prenatal diagnosis of total arhinia.
Complete or total arhinia, in which there is absence of the soft tissue of the nose, is extremely rare. The embryological origin of the defect is thought to be maldevelopment of the paired nasal placodes. Available neonatal case descriptions have reported the frequent coexistence of other facial anomalies. This report is the first to describe the antenatal diagnosis of total arhinia confirmed after delivery. Sonographic views of the fetal profile, showing an absence of the nose led to consideration of the diagnosis.
Cusick
W
W
Stamford Hospital, Division of Matemal-Fetal Medicine, CT 06612, USA. mfmdoc@yahoo.com
Sullivan
C A
CA
Rojas
B
B
Poole
A E
AE
Poole
D A
DA
D000328:Adult; D016640:Diabetes, Gestational / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D009666:Nose / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000000981:diagnostic imaging*; D011256:Pregnancy Outcome; D011262:Pregnancy Trimester, Second; D019651:Plastic Surgery Procedures; D014057:Tomography, X-Ray Computed; D016216:Ultrasonography, Prenatal