Botulism-like syndrome after injections of botulinum toxin.
Botulinum type A toxin (BTA) is an orphan drug used to treat several disorders of muscle spasticity. We report the first known case of systemic botulism-like syndrome induced by BTA therapy which resulted in respiratory arrest. Clinicians should be aware that systemic effects may occur with localized BTA therapy and may be life-threatening.
Cobb
D B
DB
University of Texas Health Science Center at San Antonio, South Texas Poison Center, 78229-3900, USA.
Watson
W A
WA
Fernandez
M C
MC
D000328:Adult; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000009:adverse effects*; D001906:Botulism / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D004421:Dystonia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007267:Injections; D007440:Intubation; D012123:Pulmonary Ventilation; D012131:Respiratory Insufficiency / Q000209:etiology* / Q000628:therapy
D019274:Botulinum Toxins, Type A