title: Chloride transport by lobster hepatopancreas is facilitated by several anion antiport mechanisms.
abstract: Three anion antiporters have previously been demonstrated in lobster hepatopancreatic basolateral membrane vesicles (BLMV) to perform vital physiological functions in the crustacean. Cl(-) was shown to be transported by all three of the documented antiporters. The stilbene, 4-acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid, also known as SITS, strongly inhibited Cl(-)/SO(4)(2-), Cl(-)/oxalate(2-) and Cl(-)/HCO(3)(-) exchange. It was concluded that Cl(-) could be transported by different modes of the documented existing anion antiporters in the lobster hepatopancreatic BLMV.
authors.affiliation: Department of Physiology, College of Medicine, Box 100274, JHMHC, University of Florida, Gainesville, FL 32610, USA.
authors.forename: G A
authors.initials: GA
authors.lastname: Gerencser
authors.forename: G A
authors.initials: GA
authors.lastname: Ahearn
authors.forename: F
authors.initials: F
authors.lastname: Robbins
authors.forename: M A
authors.initials: MA
authors.lastname: Cattey
mesh_terms: D012856:4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / Q000494:pharmacology; D000818:Animals; D000838:Anions; D017920:Antiporters / Q000037:antagonists & inhibitors / Q000378:metabolism*; D001692:Biological Transport / Q000187:drug effects; D002462:Cell Membrane / Q000378:metabolism / Q000648:ultrastructure; D002712:Chlorides / Q000378:metabolism*; D004064:Digestive System / Q000378:metabolism*; D005109:Extracellular Matrix / Q000378:metabolism; D008121:Nephropidae / Q000502:physiology*
chemical_list: D000838:Anions; D017920:Antiporters; D002712:Chlorides; D012856:4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid