title: Multicomponent linchpin couplings of silyl dithianes: synthesis of the Schreiber C(16-28) trisacetonide subtarget for mycoticins A and B.
abstract: [formula: see text] An efficient synthesis of trisacetonide (+)-11, the Schreiber C(16-28) subtarget for mycoticins A and B, is described. The key synthetic transformation entails a one-flask, five-component linchpin coupling tactic.
authors.affiliation: Department of Chemistry, Monell Chemical Senses Center, University of Pennsylvania, Philadelphia 19104, USA. smithab@sas.upenn.edu
authors.forename: A B
authors.initials: AB
authors.lastname: Smith
authors.forename: S M
authors.initials: SM
authors.lastname: Pitram
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D018942:Macrolides; D009682:Magnetic Resonance Spectroscopy
chemical_list: D000900:Anti-Bacterial Agents; D018942:Macrolides; C410430:mycoticin A; C410429:mycoticin B