title: Fluoride release and antibacterial properties of new-generation tooth-colored restoratives.
abstract: The aim of this study was to compare the amounts and pattern of fluoride release and antibacterial properties of new-generation restoratives over a 35-day period. Materials evaluated included fluoride-releasing composites (Tetric, Experimental X), compomers (Dyract, Compoglass), and a resin-modified glass-ionomer cement (Fuji II LC). A conventional glass ionomer (Fuji II Cap) was used as a control for fluoride-release testing. Five samples of each restorative material were evaluated for daily fluoride release over a 35-day period by means of ion chromatography. Ranking of materials from least to greatest total fluoride release over 35 days was as follows: Tetric < Experimental X < Dyract < Fuji II LC < Compoglass < Fuji II Cap. Fuji II Cap had significantly greater fluoride release than all other materials evaluated. Fuji II Cap, Fuji II LC, and Compoglass had similar patterns of fluoride release characterized by a high initial release that was many times that released later. The fluoride-releasing composites evaluated stopped releasing fluoride by day 14. Antibacterial testing was conducted using the agar diffusion inhibitory test. Five samples of each restorative were assessed at baseline and weekly intervals up to 35 days. The microorganisms used were Lactobacillus casei, Streptococcus mutans, and Streptococcus sobrinus. IRM, a zinc oxide/eugenol cement, was used as the baseline control. None of the restorative materials evaluated affected the growth of L casei, S sobrinus, or S mutans at all time periods including baseline, where fluoride was detected in the agar beneath the specimen disks. There was no correlation noted between fluoride-release potential and antibacterial properties.
authors.affiliation: National University of Singapore, Faculty of Dentistry, Department of Restorative Dentistry, Republic of Singapore.
authors.forename: A U
authors.initials: AU
authors.lastname: Yap
authors.forename: E
authors.initials: E
authors.lastname: Khor
authors.forename: S H
authors.initials: SH
authors.lastname: Foo
mesh_terms: D000891:Anti-Infective Agents, Local / Q000737:chemistry*; D002327:Cariostatic Agents / Q000737:chemistry*; D020770:Compomers / Q000737:chemistry; D003188:Composite Resins / Q000737:chemistry; D003738:Dental Cements / Q000737:chemistry*; D003793:Dental Restoration, Permanent / Q000379:methods*; D005459:Fluorides / Q000737:chemistry*; D005899:Glass Ionomer Cements / Q000737:chemistry; D007778:Lactobacillus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D013291:Streptococcus / Q000187:drug effects
chemical_list: D000891:Anti-Infective Agents, Local; D002327:Cariostatic Agents; D020770:Compomers; D003188:Composite Resins; D003738:Dental Cements; D005899:Glass Ionomer Cements; D005459:Fluorides