Association analysis between bilateral convergent strabismus with exophthalmus and milk production traits in dairy cattle.
Bilateral convergent strabismus with exophthalmus (BCSE) is characterized in cattle by a symmetrical antero-medial rotation and protrusion of the eyeballs. This eye defect is caused by an inherited, centrally insufficient function of the eye muscles recti laterales and retractores. In German Brown cattle a monogenic, autosomal dominant inheritance proved to be most probable in complex segregation analysis. In our study running between October 1993 and May 1995 a total of 200 affected German Brown cows was studied. The investigation of the association between milk production traits and BCSE was based on 10,960 German Brown cows. The analysis revealed no significant differences between affected and non-affected cows, nor between cow families with and without affected members. There was no indication of an association between milk production traits and occurrence of BCSE within cow families. Linkage or pleiotropy of the BCSE locus with quantitative trait loci for milk production traits may be rather unlikely.
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Institut für Tierzucht und Vererbungsforschung, Tierärztlichen Hochschule, Hannover, Germany.
Gerst
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D000818:Animals; D001947:Breeding / Q000706:statistics & numerical data; D002417:Cattle; D002418:Cattle Diseases / Q000235:genetics* / Q000503:physiopathology; D004948:Esotropia / Q000150:complications / Q000235:genetics / Q000662:veterinary*; D005094:Exophthalmos / Q000150:complications / Q000235:genetics / Q000662:veterinary*; D005260:Female; D007774:Lactation / Q000235:genetics*; D016018:Least-Squares Analysis; D008892:Milk / Q000378:metabolism; D008894:Milk Proteins / Q000032:analysis; D008954:Models, Biological; D010375:Pedigree; D019655:Quantitative Trait, Heritable
D008894:Milk Proteins