[Treatment of hydatid cysts' residual cavities (experimental and clinical study)].
Experimental series of 60 cotton rats and 150 white mice infected with echinococcus showed that 80-100% glycerin and 3% peroxide solution were effective scolicidal solutions for inactivation of the parasite. 344 patients have been operated on for hydatid disease with inactivation of the parasite by means of these scolicidal solutions. Glycerin during the surgical management of the hydatid cysts is effective and harmless in uncomplicated hydatid liver disease and any hydatid pulmonary cysts. Glycerin is contraindicated in complicated hydatid liver disease because of immunity disturbance. In complicated hydatid liver disease management of the hydatid cysts by 3% peroxide is effective and harmless. It is necessary to correct the hydatid liver disease patients' immunity in the preoperative and postoperative periods. Tactivin and antiechinococcus drug SK-1 are effective immunomodulators in hydatid liver disease.
Biriukov
Iu V
IuV
Streliaeva
A V
AV
Sadykov
V M
VM
Tursunov
B S
BS
Rasulov
S M
SM
Kovalenko
F P
FP
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D000923:Anticestodal Agents / Q000627:therapeutic use*; D000075202:Contraindications; D004359:Drug Therapy, Combination; D004444:Echinococcosis, Hepatic / Q000188:drug therapy* / Q000276:immunology / Q000601:surgery; D004445:Echinococcosis, Pulmonary / Q000188:drug therapy* / Q000276:immunology / Q000601:surgery; D004446:Echinococcus / Q000187:drug effects / Q000302:isolation & purification; D005990:Glycerol / Q000627:therapeutic use; D006801:Humans; D006861:Hydrogen Peroxide / Q000627:therapeutic use; D007111:Immunity, Cellular / Q000187:drug effects; D007432:Intraoperative Period; D051379:Mice; D010455:Peptides / Q000627:therapeutic use; D051381:Rats; D016205:Sigmodontinae; D013949:Thymus Extracts / Q000627:therapeutic use; D016896:Treatment Outcome
D000276:Adjuvants, Immunologic; D000923:Anticestodal Agents; D010455:Peptides; D013949:Thymus Extracts; C036191:T-activin; D006861:Hydrogen Peroxide; D005990:Glycerol