title: The effects of Valette on skin and hair: a post-marketing surveillance study.
abstract: The effects of Valette--an oral contraceptive containing ethinyloestradiol 0.03 mg and the antiandrogenic progestogen dienogest 2.0 mg--on the skin and hair were surveyed over 63,474 cycles in 10,718 women in routine gynaecological practice. Improvements were greatest in women with severe or moderate androgen-related symptoms. After six cycles, < 1% of women had severely greasy hair and 6% had moderate greasiness, compared with 11% and 27% at baseline; fewer hair washes were needed per week. The incidence of severe and moderately greasy skin disorders fell from 16% to < 1%, and from 39% to 7.5%, respectively. Self-assessments indicated less greasy hair and improved greasy skin disorders in 70% and 81% of women, respectively. The overall effect of Valette on the skin and hair was rated very good or good by 87.5% of women. These results confirm previous observations of a beneficial effect of Valette on androgen-related skin and hair conditions.
authors.affiliation: Department of Medical Affairs, Jenapharm GmbH & Co KG, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Zimmermann
authors.forename: K H
authors.initials: KH
authors.lastname: Wisser
authors.forename: H
authors.initials: H
authors.lastname: Dietrich
mesh_terms: D000293:Adolescent; D000328:Adult; D003277:Contraceptives, Oral, Combined / Q000494:pharmacology / Q000627:therapeutic use*; D045166:Estradiol Congeners / Q000627:therapeutic use*; D004997:Ethinyl Estradiol / Q000627:therapeutic use*; D005260:Female; D005858:Germany; D006197:Hair / Q000187:drug effects*; D006801:Humans; D009277:Nandrolone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D010349:Patient Compliance; D011358:Product Surveillance, Postmarketing; D012867:Skin / Q000187:drug effects*
chemical_list: D003277:Contraceptives, Oral, Combined; D045166:Estradiol Congeners; D004997:Ethinyl Estradiol; D009277:Nandrolone