title: Strategies in complex disease mapping.
abstract: Dissecting the genetics of common, complex disorders remains one of the great challenges in human genetics. The acceleration of human genome sequence determination, improvements in informatics, large-scale identification of single nucleotide polymorphisms and improvements in scoring technologies have now increased the feasibility of identifying polymorphisms that predispose to common disease.
authors.affiliation: Department of Medical Genetics, Wellcome Trust/MRC Building, University of Cambridge, Wellcome Trust Centre for Molecular Mechanisms of Disease, Addenbrookes Hospital, Cambridge, CB2 2XY, UK.
authors.forename: G C
authors.initials: GC
authors.lastname: Johnson
authors.forename: J A
authors.initials: JA
authors.lastname: Todd
mesh_terms: D002874:Chromosome Mapping; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D005826:Genetics, Medical / Q000379:methods; D015894:Genome, Human; D006801:Humans; D011110:Polymorphism, Genetic