New polyfunctional magnesium reagents for organic synthesis
The iodine-magnesium exchange reaction allows the preparation of polyfunctional aryl, heteroaryl, or alkenyl magnesium reagents at low temperature. These reagents display the typical reactivity of Grignard compounds and undergo various copper-catalyzed reactions such as allylation or 1,4-addition. Using this halogen-metal exchange reaction, it was possible to generate polyfunctional magnesium reagents on the solid phase.
Rottlander
M
Institut fur Organische Chemie der Universitat, Munchen, Germany.
Boymond
L
Berillon
L
Lepretre
A
Varchi
G
Avolio
S
Laaziri
H
Queguiner
G
Ricci
A
Cahiez
G
Knochel
P