Ductal sebaceoma (sebomatricoma).
We present a case of an unusual tumour arising in the forehead of a 52-year-old female. The tumour, diagnosed as sebaceoma (or sebomatricoma), showed predominantly differentiation towards ductal protion of the sebaceous gland. It was marked in tissue sections as areas of "poroid" cells and the tumour required differentiation from poroma. Focal areas of necrosis en masse in the present tumour contributed further difficulties in to the differential diagnosis. As single multivacuolar sebocytes were found and no cuticular cells could be identified, the tumour was diagnosed as ductal sebaceoma (sebomatricoma). The aspects of morphological distinction between sebomatricomas and poromas are presented with its clinical implications.
Biernat
W
W
Department of Tumour Pathology, Medical University, MSW Hospital, Lódź. biernat@psk2.am.lodz.pl
Biernat
S
S
D003937:Diagnosis, Differential; D050701:E2F6 Transcription Factor; D005260:Female; D005546:Forehead; D006801:Humans; D007633:Keratins / Q000032:analysis; D008875:Middle Aged; D009336:Necrosis; D012097:Repressor Proteins / Q000032:analysis; D012626:Sebaceous Gland Neoplasms / Q000378:metabolism / Q000473:pathology*; D014157:Transcription Factors / Q000032:analysis
D050701:E2F6 Transcription Factor; C491744:E2F6 protein, human; D012097:Repressor Proteins; D014157:Transcription Factors; D007633:Keratins