[Spinal cord compression secondary to extramedullary hematopoiesis in a patient with thalassemia].
A 19-year-old man with homozygous beta thalassemia presented with signs of thoracic spinal cord compression secondary to extramedullary hematopoiesis. The patient was treated with hypertransfusion and hydroxyurea. After two months, clinical signs had resolved and magnetic resonance imaging showed significant regression of the extradural mass. Pathophysiology and therapeutic options in this condition are briefly discussed.
Bruneteau
G
G
Service de Neurologie, Hôpital Tenon, Paris, France.
Fénelon
G
G
Khalil
A
A
Kanfer
A
A
Girot
R
R
D000328:Adult; D005500:Follow-Up Studies; D006411:Hematopoiesis, Extramedullary / Q000235:genetics / Q000502:physiology*; D006720:Homozygote; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013116:Spinal Cord / Q000473:pathology; D013117:Spinal Cord Compression / Q000175:diagnosis* / Q000235:genetics; D017086:beta-Thalassemia / Q000175:diagnosis* / Q000235:genetics