Histological comparison of chronic hepatitis B and C in an Indian population.
Many studies have shown that steatosis, lymphoid aggregates or follicles and bile duct injury on histology are more consistently associated with chronic hepatitis C than chronic hepatitis B. We compared liver biopsies of 30 patients of chronic hepatitis B with an equal number of age matched patients with chronic hepatitis C. Steatosis, lymphoid aggregates or follicles and bile duct injury were noted in 66.6%, 36.6% and 26.6% cases respectively of chronic hepatitis B as compared to 70%, 33.3% and 30% cases respectively of chronic hepatitis C. Thus none of the features were considered distinctive of HCV infection.
Malhotra
V
V
Department of Pathology, G. B. Pant Hospital, Bahadur Shah Zafar Marg, New Delhi, India.
Sakhuja
P
P
Gondal
R
R
Sarin
S K
SK
Siddhu
M
M
Dutt
N
N
D000328:Adult; D015415:Biomarkers / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006508:Hepatitis Antibodies / Q000097:blood; D018963:Hepatitis Antigens / Q000097:blood; D019694:Hepatitis B, Chronic / Q000276:immunology / Q000473:pathology*; D019698:Hepatitis C, Chronic / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007194:India; D008297:Male
D015415:Biomarkers; D006508:Hepatitis Antibodies; D018963:Hepatitis Antigens