The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?
The role of the 3' untranslated region in posttranscriptional regulation of mRNA expression is being elucidated. Here we describe diseases arising from anomalies in this region, that affect the expression of one or more genes.
Conne
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Department of MorphologyFaculty of Medicine University of Geneva CMU, 1211 Geneva 4, Switzerland. beatrice.conn@medecine.unige.ch
Stutz
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Vassalli
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D020413:3' Untranslated Regions / Q000502:physiology*; D000818:Animals; D006801:Humans; D009223:Myotonic Dystrophy / Q000235:genetics; D014176:Protein Biosynthesis; D012323:RNA Processing, Post-Transcriptional; D020871:RNA Stability
D020413:3' Untranslated Regions