Thonningianins A and B, new antioxidants from the African medicinal herb Thonningia sanguinea.
Two new ellagitannins, thonningianins A (1) and B (2), have been isolated from the African medicinal herb Thonningia sanguinea and their structures elucidated by interpretation of spectroscopic data. Both 1 and 2 showed strong free radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) as shown by ESR analysis.
Ohtani
I I
II
Department of Chemistry, Biology, and Marine Science, University of the Ryukyus, Nishihara, Okinawa 903-0213, Japan.
Gotoh
N
N
Tanaka
J
J
Higa
T
T
Gyamfi
M A
MA
Aniya
Y
Y
D000349:Africa; D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology; D015764:Bepridil / Q000031:analogs & derivatives / Q000737:chemistry; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers / Q000302:isolation & purification / Q000494:pharmacology; D005609:Free Radicals / Q000737:chemistry; D047348:Hydrolyzable Tannins; D009682:Magnetic Resonance Spectroscopy; D010851:Picrates; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013634:Tannins / Q000302:isolation & purification* / Q000494:pharmacology
D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005609:Free Radicals; D047348:Hydrolyzable Tannins; D010851:Picrates; D013634:Tannins; C411320:thonningianin A; C411321:thonningianin B; D015764:Bepridil; C004931:1,1-diphenyl-2-picrylhydrazyl