A chiral rhodium complex for rapid asymmetric transfer hydrogenation of imines with high enantioselectivity.
[formula: see text] A chiral rhodium complex, (R)-Cp*RhCl[(1S,2S)-p-TsNCH(C6H5)CH(C6H5)NH2] (1a, (S,S)-Cp*RhClTsDPEN), generated from [Cp*RhCl2]2 and (1S,2S)-N-p-toluenesulfonyl-1,2-diphenylethylenediamine [(S,S)-TsDPEN], and its enantiomer 1b were found to provide superior catalysts for the rapid, high-yielding, asymmetric transfer hydrogenation of some heterocyclic imines, using an HCO2H-Et3N azeotrope as the hydrogen source.
Mao
J
J
Department of Chemistry, University of Tennessee, Knoxville 37996-1600, USA.
Baker
D C
DC
D006859:Hydrogen / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
D007097:Imines; D006859:Hydrogen; D012238:Rhodium