title: Signal transduction: response regulators on and off.
abstract: High resolution structures of the active phosphorylated forms of two-component response regulators have recently been reported. The results provide a basis for understanding how metabolic energy is coupled to signal transduction in cellular regulatory networks.
authors.affiliation: Department of Molecular Biology, Princeton University, NJ 08544, USA.
authors.forename: J
authors.initials: J
authors.lastname: Stock
authors.forename: S
authors.initials: S
authors.lastname: Da Re
mesh_terms: D000251:Adenosine Triphosphatases / Q000737:chemistry* / Q000378:metabolism*; D001426:Bacterial Proteins; D008565:Membrane Proteins / Q000737:chemistry* / Q000378:metabolism*; D000072236:Methyl-Accepting Chemotaxis Proteins; D008958:Models, Molecular; D011487:Protein Conformation; D011494:Protein Kinases / Q000737:chemistry / Q000378:metabolism; D017433:Protein Structure, Secondary; D015398:Signal Transduction
chemical_list: D001426:Bacterial Proteins; D008565:Membrane Proteins; D000072236:Methyl-Accepting Chemotaxis Proteins; D011494:Protein Kinases; D000251:Adenosine Triphosphatases