title: Generation of hydrogen radicals for reactivity studies in Fourier transform ion cyclotron resonance mass spectrometry.
abstract: An efficient technique for generation of H* (D*) radicals in Fourier transform ion cyclotron resonance (FTICR) mass spectrometry is described. The method allows the probing of the reactivity of gas-phase H* radicals towards various ions isolated in the cell of an FTICR mass spectrometer. Results on interactions of H* and D* radicals with trapped positive or negative C60 fullerene ions, as well as singly charged peptide ions, are presented. Hydrogen radical addition or H/D-exchange reactions between trapped ions and free H* (D*) radicals were observed. Potential implementation of the technique for probing the gas-phase three-dimensional structures of polyatomic ions is discussed as well.
authors.affiliation: Department of Chemistry and Biochemistry, University of Maryland, College Park 20742, USA. demirev@wam.umd.edu
authors.forename: P A
authors.initials: PA
authors.lastname: Demirev
mesh_terms: D001920:Bradykinin / Q000737:chemistry; D002244:Carbon / Q000737:chemistry; D017357:Cyclotrons; D003903:Deuterium / Q000737:chemistry; D005583:Fourier Analysis; D005609:Free Radicals / Q000737:chemistry; D037741:Fullerenes; D006859:Hydrogen / Q000737:chemistry*; D013058:Mass Spectrometry / Q000379:methods; D010455:Peptides / Q000737:chemistry
chemical_list: D005609:Free Radicals; D037741:Fullerenes; D010455:Peptides; D002244:Carbon; D006859:Hydrogen; D003903:Deuterium; C069837:fullerene C60; D001920:Bradykinin