Esophageal varices. I. Clinical presentation, medical therapy, and endoscopic therapy.
The last half century has witnessed great advances in the understanding of the pathogenesis and natural history of portal hypertension in cirrhotics. Several pharmacologic and endoscopic techniques have been developed for the treatment of portal hypertension. The use of these agents in a given patient must be based on an understanding of the stage in the natural history of the disease and the relative efficacy and safety of the available treatment options.
Luketic
V A
VA
Department of Medicine, Medical College of Virginia Commonwealth University, Richmond, USA. vluketic@hsc.vcu.edu
Sanyal
A J
AJ
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002404:Catheterization; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D016145:Endoscopy, Digestive System; D004932:Esophageal and Gastric Varices / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis / Q000517:prevention & control; D006801:Humans; D008026:Ligation; D012597:Sclerosing Solutions / Q000627:therapeutic use; D015911:Sclerotherapy / Q000379:methods*; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D012597:Sclerosing Solutions