Differential interaction of somatosensory inputs in the human primary sensory cortex: a magnetoencephalographic study.
OBJECTIVE
Somatosensory evoked magnetic fields (SEFs) were recorded to investigate the interaction of the somatosensory inputs using the modality of electrical finger stimulation in 6 normal subjects.


METHODS
Electrical stimuli were given to the index (II), middle (III) or little (V) fingers individually, and also to pairs of either the II and III simultaneously, or the II and V simultaneously. The interaction ratio (IR) was calculated as the ratio of the SEF amplitude by simultaneous two-finger stimulation to the arithmetically summed SEF amplitudes of two individual-finger stimulations.


RESULTS
SEFs showed 3 major components: N22m, P30m and P60m. The N22m and P60m revealed a clear somatotopic organization in the primary sensory cortex (S1) in the sequence of II, III and V, while the P30m showed a cluster with medial location compared with N22m and P60m in S1. The N22m had a significantly greater IR in II and III stimulation compared to that in II and V stimulation. The P60m also showed a similar trend in the IR but was greater than that of N22m. In contrast, the IR in P30m showed no such tendency.


CONCLUSIONS
The interaction of S1 was most influenced when adjacent receptive fields were activated in the modality of electrical finger stimulation. Our results were consistent with the concept that the Brodmann's areas in S1 which produce the 3 components of the SEFs have different functional organization.
Ishibashi
H
H
Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University 60, 812-8582, Fukuoka, Japan. hideaki@toq.or.jp
Tobimatsu
S
S
Shigeto
H
H
Morioka
T
T
Yamamoto
T
T
Fukui
M
M
D000328:Adult; D000704:Analysis of Variance; D001931:Brain Mapping; D004558:Electric Stimulation; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D005385:Fingers / Q000294:innervation; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008297:Male; D011930:Reaction Time; D013003:Somatosensory Cortex / Q000502:physiology*