title: Mycoplasma genitalium in non-gonococcal urethritis--a study in Swedish male STD patients.
abstract: Urethral swab specimens obtained from 101 men attending an STD clinic were examined for the presence of Mycoplasma genitalium by polymerase chain reaction (PCR) amplification. Fifty patients had non-gonococcal urethritis (NGU), and 51 patients were included as controls without urethritis. M. genitalium DNA was detected in 13 (26%) of the urethritis patients and in 5 (10%) of the control patients (P=0.06). No patient positive for M. genitalium had a simultaneous chlamydial infection. Thus, in the 36 patients with non-chlamydial NGU, the prevalence of M. genitalium infection was 36% (P=0.007 compared with controls). All patients with M. genitalium positive urethritis had a high grade urethritis defined as >10 polymorphonuclear cells per high power microscopical field. Compared with the control group, those with M. genitalium positive urethritis had more often had a history of urethritis than had those with chlamydial NGU or those with M. genitalium negative, non-chlamydial NGU.
authors.affiliation: Department of Dermatovenereology, Huddinge University Hospital, Karolinska Institutet, Sweden.
authors.forename: E
authors.initials: E
authors.lastname: Björnelius
authors.forename: P
authors.initials: P
authors.lastname: Lidbrink
authors.forename: J S
authors.initials: JS
authors.lastname: Jensen
mesh_terms: D000293:Adolescent; D000328:Adult; D002692:Chlamydia trachomatis; D004269:DNA, Bacterial / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009174:Mycoplasma / Q000187:drug effects / Q000302:isolation & purification*; D009175:Mycoplasma Infections / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D009344:Neisseria gonorrhoeae; D009504:Neutrophils; D016133:Polymerase Chain Reaction; D015995:Prevalence; D015231:Sexually Transmitted Diseases, Bacterial / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D013548:Sweden / Q000453:epidemiology; D014526:Urethritis / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology
chemical_list: D004269:DNA, Bacterial