title: [Parallel variation in mitochondrial DNA type 16278T in genome of the migrant population of Northeast Asia and other caucasoid populations].
abstract: Types of mtDNA with +16274EcoRV, which had been previously found in East Slavonic residents of Magadan, were identified on the basis of published data on nucleotide sequences of the hypervariable segment I (HVSI) of the mtDNA control region. These mtDNA types occurred in Slavs at a frequency of 7-14% and were assigned to four mitotype groups (1, 2A, 3B, and 5) restricted to Caucasoid populations. Regarding the evolution of mtDNA, this fact indicates that the C-T transition at position 16,278 arose independently in various groups of mtDNA types in Caucasoids. A new subgroup was isolated in Caucasoid group 5. One of the key mutations in this subgroup was variant +16398HaeIII (transition A-G at position 16,399), which was earlier detected in Russian populations at a relatively high frequency.
authors.affiliation: Institute of Biological Problems of the Far North, Russian Academy of Sciences, Magadan, Russia.
authors.forename: B A
authors.initials: BA
authors.lastname: Maliarchuk
authors.forename: M V
authors.initials: MV
authors.lastname: Derenko
mesh_terms: D001208:Asia; D004272:DNA, Mitochondrial / Q000235:genetics*; D004641:Emigration and Immigration; D014644:Genetic Variation; D005828:Genetics, Population; D015894:Genome, Human; D006801:Humans; D044465:White People
chemical_list: D004272:DNA, Mitochondrial