title: Theoretical study of temperature elevation at muscle/bone interface during ultrasound hyperthermia.
abstract: This paper examines the distributions of the SAR (specific absorption rate) ratio and temperature elevation when an ultrasound beam propagates through the interface of muscle and bone. This interface is regarded as a flat boundary to partition the energy of the ultrasound beam, and the analytical solution of temperature distribution is based on the steady-state bio-heat transfer equation. The parameters considered are the incident angle of ultrasound beam, the ultrasound frequency, the acoustic attenuation coefficients of refracted longitudinal and shear waves in bone, and the blood perfusion in muscle. The results show that the peak of the SAR ratio is always at the interface of muscle and bone, while the peak of temperature is located in the bone region beyond the interface. A muscle with lower perfusion or a bone with higher acoustic attenuation results in the shifting of the temperature peak closer to the interface. It is more difficult to heat a higher perfused muscle in front of a bone using a lower frequency ultrasound since the temperature elevation for bone relative to muscle is greater.
authors.affiliation: Institute of Biomedical Engineering, National Taiwan University, Taipei.
authors.forename: W L
authors.initials: WL
authors.lastname: Lin
authors.forename: C T
authors.initials: CT
authors.lastname: Liauh
authors.forename: Y Y
authors.initials: YY
authors.lastname: Chen
authors.forename: H C
authors.initials: HC
authors.lastname: Liu
authors.forename: M J
authors.initials: MJ
authors.lastname: Shieh
mesh_terms: D000162:Acoustics; D001698:Biomedical Engineering; D055592:Biophysical Phenomena; D001703:Biophysics; D001842:Bone and Bones / Q000503:physiopathology; D006801:Humans; D008954:Models, Biological; D009132:Muscles / Q000503:physiopathology; D009369:Neoplasms / Q000503:physiopathology / Q000628:therapy; D013696:Temperature; D014464:Ultrasonic Therapy / Q000379:methods*