title: Antibacterial susceptibility patterns of Pseudomonas strains isolated from chronic canine otitis externa.
abstract: Development of antibiotic resistance in bacteria is a problem of great concern. It is important to establish the convenience of antimicrobial susceptibility tests in animal infections. The aim of this study was to test the susceptibility to antibiotics of Pseudomonas strains isolated from chronic canine otitis externa. We tested 23 strains of Pseudomonas: 19 Ps. aeruginosa, three Ps. fluorescens and one Pseudomonas spp. The most effective antibiotics were tobramycin (100% susceptible), marbofloxacin (91.3%) and ceftazidime (91.3%). Ticarcillin and gentamicin, commonly used for the treatment of otitis externa also showed good results (susceptibility of strains was 86 and 65.2% respectively). Lower susceptibility was found using enrofloxacin (52.1%) probably due to its indiscriminate use. We emphasize the need for a rational policy of antibiotic prescribing in order to prevent the selection of resistant strains.
authors.affiliation: Departamento de Microbiología, Universidad de Las Palmas de Gran Canaria, Spain.
authors.forename: J L
authors.initials: JL
authors.lastname: Martín Barrasa
authors.forename: P
authors.initials: P
authors.lastname: Lupiola Gómez
authors.forename: Z
authors.initials: Z
authors.lastname: González Lama
authors.forename: M T
authors.initials: MT
authors.lastname: Tejedor Junco
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002442:Ceftazidime / Q000494:pharmacology; D002908:Chronic Disease; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D004352:Drug Resistance, Microbial; D024841:Fluoroquinolones; D008826:Microbial Sensitivity Tests; D010032:Otitis Externa / Q000382:microbiology / Q000662:veterinary*; D011549:Pseudomonas / Q000145:classification / Q000187:drug effects*; D011552:Pseudomonas Infections / Q000382:microbiology / Q000662:veterinary*; D015363:Quinolones / Q000494:pharmacology; D014031:Tobramycin / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D015363:Quinolones; C080260:marbofloxacin; D002442:Ceftazidime; D014031:Tobramycin