title: [Corticosteroid-induced epidural lipomatosis].
abstract: Epidural lipomatosis is a rare disease, most often associated with chronic administration of exogenous steroids. We report the case of a 69-year-old man treated with 20mg prednisolone daily for 11 years because of polyarthritis. The patient complained of back pain associated with severe weakness of his lower limbs and brisk reflexes, with a progressive onset over one year. MRI showed epidural lipomatosis narrowing the epidural spaces from T-3 to T-10. Tapering of steroids was associated with slow but positive resolution of his symptoms.
authors.affiliation: Fédération de Neurologie Mazarin, Hôpital de la Salpêtrière, Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Jalladeau
authors.forename: A F
authors.initials: AF
authors.lastname: Carpentier
authors.forename: M
authors.initials: M
authors.lastname: Napolitano
authors.forename: J Y
authors.initials: JY
authors.lastname: Delattre
mesh_terms: D000368:Aged; D015535:Arthritis, Psoriatic / Q000188:drug therapy*; D003937:Diagnosis, Differential; D004824:Epidural Space / Q000187:drug effects / Q000473:pathology; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008068:Lipomatosis / Q000139:chemically induced* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage / Q000009:adverse effects*; D013116:Spinal Cord / Q000187:drug effects / Q000473:pathology; D013117:Spinal Cord Compression / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone