title: Maternal levels of vitamin E in normal and preeclamptic pregnancy.
abstract: Vitamin E, a potent antioxidant, may play a role in preventing preeclampsia. Maternal blood samples were collected between 28 and 40 weeks' gestation from women with mild preeclampsia (n=17), women with severe preeclampsia (n=16) and the control group (n=15). This control group was consisted of 15 pregnant women without hypertension episode during their pregnancy. Vitamin E levels were significantly higher in normotensive pregnant women (1.00+/-0.20 mg/dL) than in those with mild (0.56+/-0.15 mg/dL) or severe (0.37+/-0.75 mg/dL) preeclampsia (P<0.001). In preeclamptic women, when systolic blood pressure increases, maternal levels of vitamin E significantly decrease (P<0.05), also when diastolic blood pressure increases, maternal levels of vitamin E significantly decrease (P<0.05). Measurement of vitamin E concentration in plasma may be useful as a prognostic marker of the likely development of preeclampsia.
authors.affiliation: Dr Zekai Tahir Burak Women's Hospital, Ankara, Turkey. perinatologyak@superonline.com
authors.forename: D
authors.initials: D
authors.lastname: Akyol
authors.forename: T
authors.initials: T
authors.lastname: Mungan
authors.forename: H
authors.initials: H
authors.lastname: Görkemli
authors.forename: G
authors.initials: G
authors.lastname: Nuhoglu
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D010298:Parity; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy / Q000097:blood*; D011263:Pregnancy Trimester, Third; D011446:Prospective Studies; D012016:Reference Values; D013050:Spectrometry, Fluorescence; D014810:Vitamin E / Q000097:blood*
chemical_list: D014810:Vitamin E