title: Induction of CD44 expression in stab wounds of the brain: long term persistence of CD44 expression.
abstract: We studied the expression of the hyaluronan receptor protein CD44 in the mouse brain in response to stab injuries. CD44 expression was strongly activated in the area surrounding the injury within 2 days and then persisted for over 2 months. The expression extended in a direct line the depth of the actual wound inflicted. It appears that CD44 may be involved in the wound healing processes following injury to the brain.
authors.affiliation: Department of Neurosurgery, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.
authors.forename: S S
authors.initials: SS
authors.lastname: Stylli
authors.forename: A H
authors.initials: AH
authors.lastname: Kaye
authors.forename: U
authors.initials: U
authors.lastname: Novak
mesh_terms: D000818:Animals; D001930:Brain Injuries / Q000378:metabolism*; D001932:Brain Neoplasms / Q000378:metabolism; D005786:Gene Expression Regulation; D005910:Glioma / Q000378:metabolism; D018960:Hyaluronan Receptors / Q000235:genetics / Q000378:metabolism*; D007150:Immunohistochemistry / Q000379:methods; D051379:Mice; D013194:Staining and Labeling / Q000379:methods; D013997:Time Factors; D014951:Wounds, Stab / Q000378:metabolism*
chemical_list: D018960:Hyaluronan Receptors