title: Protease injury in the development of COPD: Thomas A. Neff Lecture.
authors.affiliation: Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. hchapman@rics.bwh.harvard.edu
authors.forename: H A
authors.initials: HA
authors.lastname: Chapman
authors.forename: G P
authors.initials: GP
authors.lastname: Shi
mesh_terms: D000818:Animals; D015415:Biomarkers; D003546:Cysteine Endopeptidases / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism*; D005109:Extracellular Matrix / Q000201:enzymology; D006801:Humans; D019272:Leukocyte Elastase / Q000378:metabolism; D008173:Lung Diseases, Obstructive / Q000201:enzymology / Q000209:etiology*; D011379:Prognosis; D012720:Severity of Illness Index; D000515:alpha 1-Antitrypsin / Q000378:metabolism; D019896:alpha 1-Antitrypsin Deficiency / Q000150:complications / Q000201:enzymology
chemical_list: D015415:Biomarkers; D000515:alpha 1-Antitrypsin; D010450:Endopeptidases; D019272:Leukocyte Elastase; D003546:Cysteine Endopeptidases