title: Interobserver variability of the measurement of the mortality probability models (MPM II) in the assessment of severity of illness.
abstract: OBJECTIVE
  To assess the interobserver variability of the measurement of the MPM II system.
  
  
  METHODS
  Random sample of an inception cohort.
  
  
  METHODS
  Fifteen adult medical and surgical intensive care units (ICUs) in Spain.
  
  
  METHODS
  A 5% random sample (n = 119) of 2332 patients consecutively admitted in the ICU, aged 18 years or older.
  
  
  METHODS
  Prospective data collection during the stay of the patient in the ICU. Repeated data collection, after the patient's hospital discharge.
  
  
  RESULTS
  Demographic information, length-of-stay and vital status at both ICU and hospital discharge, as well as all variables necessary for computing the MPM II system were measured. Interobserver variability for categorical variables was measured computing the kappa index. For interval variables the interobserver variability was assessed by the intraclass correlation coefficient, the paired t-test, and linear regression. In the MPM II0 index, the variables coma, heart rate, systolic blood pressure, chronic renal insufficiency, metastatic neoplasm, acute renal failure, cardiac dysrhythmia and cardiopulmonary resuscitation, showed moderate or low levels of agreement. In the MPM II24 index, the variables coma or deep stupor, PaO2 and prothrombin time showed low or moderate interobserver agreement. Agreement for the MPM II probability of death was high, although the external observer obtained a lower estimation than the hospital observer.
  
  
  CONCLUSIONS
  The MPM II severity system showed a high level of stability when used in groups of patients. Nevertheless, the observed variability in some variables means that it should be used with caution for individual patients.
authors.affiliation: Centre d'Estudis, Programes i Serveis Sanitaris, Fundació Parc Taulí de Sabadell, Spain. mrue@cspt.es
authors.forename: M
authors.initials: M
authors.lastname: Rué
authors.forename: C
authors.initials: C
authors.lastname: Valero
authors.forename: S
authors.initials: S
authors.lastname: Quintana
authors.forename: A
authors.initials: A
authors.lastname: Artigas
authors.forename: M
authors.initials: M
authors.lastname: Alvarez
mesh_terms: D000328:Adult; D015331:Cohort Studies; D003422:Critical Care / Q000592:standards*; D016638:Critical Illness / Q000401:mortality*; D005260:Female; D006801:Humans; D008297:Male; D015233:Models, Statistical; D015588:Observer Variation; D011446:Prospective Studies; D011897:Random Allocation; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D013030:Spain / Q000453:epidemiology