A new method for protein domain recognition.
A fuzzy cluster method is presented to recognize protein domains. This algorithm can identify domains globally. A protein structure set was used to test the algorithm. Among 219 proteins, 66.7% yielded results that agreed with the reference definitions, 30.6% showed minor differences, and only 2.7% (six proteins) showed major differences with the reference. The new method is more than 20 times fast than previous algorithms.
Xuan
Z Y
ZY
Protein Engineering Laboratory, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR China.
Ling
L J
LJ
Chen
R S
RS
D016000:Cluster Analysis; D003285:Contractile Proteins / Q000737:chemistry; D037102:Lectins / Q000737:chemistry; D008958:Models, Molecular; D008962:Models, Theoretical; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*
D003285:Contractile Proteins; D037102:Lectins; D011506:Proteins