title: Decreased tear secretion after laser in situ keratomileusis for high myopia.
abstract: OBJECTIVE
  To investigate the changes in tear secretion and tear film stability after excimer laser in situ keratomileusis (LASIK) for high myopia.
  
  
  METHODS
  One eye of 28 patients underwent unilateral LASIK for the correction of myopia with spherical equivalent refractions ranging from -6.37 to -18.25 D (mean, -11.98 +/- 3.45 D). Schirmer tear test values without anesthesia at 5 minutes and tear break-up time values were measured 4 weeks after LASIK. Unoperated contralateral eyes were used as a control for each patient. The Schirmer tear test and tear break-up time values were analyzed statistically using the independent t-test.
  
  
  RESULTS
  The mean Schirmer tear test value was 16.17 +/- 2.50 mm in the operated eyes and 21.07 +/- 7.03 mm in the unoperated (control) eyes of the same patients (P = .001). The mean tear break-up time value was 21.0 +/- 3.55 seconds in the operated eyes and 21.27 +/- 6.79 seconds in the control eyes (P = .85).
  
  
  CONCLUSIONS
  Tear secretion decreased following LASIK probably due to decrease in corneal sensitivity, but tear film stability appeared unaltered.
authors.affiliation: Istanbul University, Eye Research Center, Turkey.
authors.forename: C
authors.initials: C
authors.lastname: Aras
authors.forename: A
authors.initials: A
authors.lastname: Ozdamar
authors.forename: H
authors.initials: H
authors.lastname: Bahcecioglu
authors.forename: M
authors.initials: M
authors.lastname: Karacorlu
authors.forename: B
authors.initials: B
authors.lastname: Sener
authors.forename: S
authors.initials: S
authors.lastname: Ozkan
mesh_terms: D000328:Adult; D003315:Cornea / Q000378:metabolism / Q000601:surgery*; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D008297:Male; D009216:Myopia / Q000378:metabolism / Q000601:surgery*; D013666:Tears / Q000737:chemistry / Q000378:metabolism*