beta-Amyloid vasoactivity and proinflammation in microglia can be blocked by cGMP-elevating agents.
Paris
D
D
Roskamp Institute, University of South Florida, Tampa, Florida 33613, USA.
Town
T
T
Parker
T
T
Humphrey
J
J
Mullan
M
M
D016229:Amyloid beta-Peptides / Q000494:pharmacology*; D000818:Animals; D001011:Aorta / Q000187:drug effects / Q000502:physiology; D006152:Cyclic GMP / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000502:physiology*; D004176:Dipyridamole / Q000494:pharmacology; D019332:Endothelin-1 / Q000494:pharmacology; D066298:In Vitro Techniques; D007249:Inflammation; D007975:Leukotriene B4 / Q000378:metabolism; D017628:Microglia / Q000187:drug effects / Q000502:physiology*; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology*; D009599:Nitroprusside / Q000494:pharmacology*; D010446:Peptide Fragments / Q000494:pharmacology*; D051381:Rats; D014661:Vasoconstriction / Q000187:drug effects / Q000502:physiology
D016229:Amyloid beta-Peptides; D019332:Endothelin-1; D010446:Peptide Fragments; C078592:amyloid beta-protein (1-40); D009599:Nitroprusside; D007975:Leukotriene B4; C016276:8-bromocyclic GMP; D004176:Dipyridamole; D006152:Cyclic GMP