[Successful prophylaxis in a pregnancy with thrombophilic states].
It has been observed that the presence of antiphospholipid antibodies (aPL) is associated with a high incidence of fetal loss and this is thought to--a result from the vasculitis of placental circulation and subsequent thrombosis. A 38-year-old woman with second fetal loss had received oral anticoagulant after pulmonary embolism. APL were examined--anticardiolipin antibodies (aCA) were found. The third pregnancy was established and sintrom was stopped and replaced by fraxiparine 0.3 ml/24 h up to the end of the pregnancy even 20 days after delivery of a healthy baby.
Iankova
Z
Z
Bogdanova
M
M
D000074:Acenocoumarol / Q000627:therapeutic use; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D020073:Gravidity; D006801:Humans; D017762:Nadroparin / Q000627:therapeutic use; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000517:prevention & control*; D011655:Pulmonary Embolism / Q000188:drug therapy; D019851:Thrombophilia / Q000517:prevention & control*; D013997:Time Factors
D000925:Anticoagulants; D017762:Nadroparin; D000074:Acenocoumarol