Detecting Taxus poisoning in horses using liquid chromatography/mass spectrometry.
A method is described for the analysis of taxine alkaloids by liquid chromatography/mass spectrometry. It is applicable to the detection of taxine alkaloids in the stomach contents of horses in which Taxus poisoning is suspected. Analysis of a leaf extract of Taxus baccata revealed unreported alkaloids of the same relative molecular mass as taxine B and isotaxine B.
Kite
G C
GC
Royal Botanic Gardens, Kew, Richmond, Surrey, UK.
Lawrence
T J
TJ
Dauncey
E A
EA
D000470:Alkaloids / Q000032:analysis* / Q000633:toxicity; D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000662:veterinary; D008401:Gas Chromatography-Mass Spectrometry / Q000662:veterinary; D005766:Gastrointestinal Contents / Q000737:chemistry*; D006734:Horse Diseases / Q000175:diagnosis* / Q000209:etiology; D006736:Horses; D008297:Male; D010939:Plant Poisoning / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*; D010946:Plants, Medicinal; D010947:Plants, Toxic / Q000506:poisoning*; D043823:Taxoids; D020946:Taxus / Q000506:poisoning*
D000470:Alkaloids; D043823:Taxoids; C047703:taxine