[Levothyroxine treatment of the solitary thyroid nodule].
The aim of this study was to review all published randomized clinical trials evaluating the efficacy of suppressive therapy with levothyroxine for solitary thyroid nodules. No significant differences were observed in reducing the volume of benign solitary cold thyroid nodules between the placebo and levothyroxine groups.
Almodóvar Ruiz
F
F
Servicio de Endocrinología y Nutrición, Hospital Ramón y Cajal, Madrid.
Maldonado Castro
G
G
de Luis
D
D
Lahera
M
M
Varela da Costa
C
C
D006801:Humans; D010919:Placebos; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D013961:Thyroid Gland / Q000000981:diagnostic imaging; D016606:Thyroid Nodule / Q000000981:diagnostic imaging / Q000188:drug therapy*; D013974:Thyroxine / Q000627:therapeutic use*; D014463:Ultrasonography
D010919:Placebos; D013974:Thyroxine