Mechanisms of airway hypersecretion and novel therapy.
Nadel
J A
JA
Cardiovascular Research Institute, and Departments of Medicine and Physiology, University of California San Francisco, San Francisco, CA 94143-0130, USA. janadel@itsa.ucsf.edu
D000402:Airway Obstruction / Q000378:metabolism* / Q000473:pathology / Q000517:prevention & control; D000818:Animals; D002452:Cell Count / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004247:DNA / Q000032:analysis; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D066246:ErbB Receptors / Q000037:antagonists & inhibitors / Q000378:metabolism*; D020397:Goblet Cells / Q000187:drug effects / Q000378:metabolism*; D017403:In Situ Hybridization; D007322:Instillation, Drug; D008297:Male; D055271:Mucin 5AC; D009077:Mucins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D051381:Rats; D011916:Rats, Inbred F344; D014409:Tumor Necrosis Factor-alpha / Q000008:administration & dosage / Q000627:therapeutic use
C524680:Muc5ac protein, rat; D055271:Mucin 5AC; D009077:Mucins; D014409:Tumor Necrosis Factor-alpha; D004247:DNA; D066246:ErbB Receptors