title: Self-injection ictal SPECT during partial seizures.
abstract: The authors compared ictal SPECT injection performed by medical personnel with self-injection ictal SPECT in six patients with refractory temporal lobe epilepsy. Self-injection was safe and started faster. Self-injection subtraction ictal SPECT coregistered to MRI (SISCOM) was localizing in three patients who had a complex partial seizure, but only one of three patients who had a simple partial seizure, which may limit its usefulness in clinical practice. The localizing information of self-injection was better in three patients, and obviated the need for depth-EEG studies in one patient.
authors.affiliation: Department of Neurology, University Hospital Gasthuisberg, Leuven, Belgium.
authors.forename: W
authors.initials: W
authors.lastname: Van Paesschen
authors.forename: P
authors.initials: P
authors.lastname: Dupont
authors.forename: B
authors.initials: B
authors.lastname: Van Heerden
authors.forename: H
authors.initials: H
authors.lastname: Vanbilloen
authors.forename: L
authors.initials: L
authors.lastname: Mesotten
authors.forename: A
authors.initials: A
authors.lastname: Maes
authors.forename: G
authors.initials: G
authors.lastname: Van Driel
authors.forename: L
authors.initials: L
authors.lastname: Mortelmans
mesh_terms: D000328:Adult; D001931:Brain Mapping; D003545:Cysteine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004833:Epilepsy, Temporal Lobe / Q000000981:diagnostic imaging* / Q000601:surgery; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds / Q000008:administration & dosage*; D019275:Radiopharmaceuticals / Q000008:administration & dosage*; D012646:Self Administration; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation*
chemical_list: D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C059659:technetium Tc 99m bicisate; D003545:Cysteine