title: Cost-effectiveness analysis methods for the REACT Study.
abstract: The Reconditioning Exercise and Chronic Obstructive Pulmonary Disease Trial (REACT) is a two-arm randomized clinical trial designed to compare short-term versus long-term exercise intervention in terms of physical function, acute exacerbation of chronic obstructive pulmonary disease, health-related quality of life, and cost-effectiveness. Clinical trials such as REACT are now routinely paired with economic analyses, and nurses can expect to play a growing role in the conduct of these studies. This article describes a model that is useful for structuring economic evaluations of health care interventions, and illustrates a cost-effectiveness analysis that is being conducted in conjunction with the REACT study. An in-depth description of collection methods and procedures is provided, as well as a summary of recruitment and retention experience to date.
authors.affiliation: Department of Public Health Sciences, Wake Forest University School of Medicine, USA.
authors.forename: V
authors.initials: V
authors.lastname: Duren-Winfield
authors.forename: M J
authors.initials: MJ
authors.lastname: Berry
authors.forename: S A
authors.initials: SA
authors.lastname: Jones
authors.forename: D H
authors.initials: DH
authors.lastname: Clark
authors.forename: M A
authors.initials: MA
authors.lastname: Sevick
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017281:Cost of Illness; D003362:Cost-Benefit Analysis; D003625:Data Collection / Q000379:methods; D003627:Data Interpretation, Statistical; D005081:Exercise Therapy / Q000191:economics* / Q000379:methods; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000191:economics* / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D017059:Models, Econometric; D012959:Socioeconomic Factors; D013997:Time Factors