title: Subchondral metastasis: report of five cases.
abstract: Subchondral metastasis is a rare occurrence and poses a diagnostic dilemma as initial films may show a lytic lesion in the subchondral region often misinterpreted as being benign. We present five cases of subchondral metastasis as well as a review of the literature. In our cases, we present subchondral metastasis in the elbow, shoulder, and hip joints. All patients had pain over the affected joint and most presented with a lytic lesion in the subchondral bone. Three patients have died since presentation and two are doing well at last follow up visit. Subchondral metastasis is a rare entity, but it should be included in the differential of a lytic lesion in the subchondral bone.
authors.affiliation: Department of Radiology, The University of Iowa College of Medicine, The University of Iowa Hospitals and Clinics, Iowa City 52242, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Peterson
authors.forename: T A
authors.initials: TA
authors.lastname: Manning
authors.forename: J J
authors.initials: JJ
authors.lastname: Callaghan
authors.forename: G Y
authors.initials: GY
authors.lastname: El-Khoury
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019046:Bone Marrow Neoplasms / Q000556:secondary; D001859:Bone Neoplasms / Q000556:secondary*; D002289:Carcinoma, Non-Small-Cell Lung / Q000556:secondary; D002291:Carcinoma, Papillary / Q000556:secondary; D002292:Carcinoma, Renal Cell / Q000556:secondary; D002294:Carcinoma, Squamous Cell / Q000556:secondary; D004550:Elbow; D017809:Fatal Outcome; D005260:Female; D005266:Femoral Neoplasms / Q000556:secondary; D006801:Humans; D006811:Humerus; D007680:Kidney Neoplasms / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D020069:Shoulder Pain / Q000209:etiology; D012878:Skin Neoplasms / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology