Hereditary congenital cataracts associated with sickle cell anaemia in a Nigerian family.
Pedigrees of hereditary disorders are rarely reported from sub-Saharan countries because of difficulties inherent in obtaining reliable family histories, case tracing and follow-up. This report relates to a four-generation family in northern Nigeria with dominantly inherited cataracts associated with recessively inherited sickle cell anaemia. It highlights the need for genetic counselling services in clinical practice in the region.
Babalola
O E
OE
Rachel Eye Center, Garki, Abuja, Nigeria.
Danboyi
P
P
Abiose
A A
AA
D000328:Adult; D000368:Aged; D000755:Anemia, Sickle Cell / Q000235:genetics* / Q000517:prevention & control; D002386:Cataract / Q000151:congenital* / Q000235:genetics* / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D005260:Female; D005799:Genes, Dominant; D005817:Genetic Counseling; D005820:Genetic Testing; D005838:Genotype; D006801:Humans; D007223:Infant; D008297:Male; D008487:Medical History Taking; D008875:Middle Aged; D009549:Nigeria; D010375:Pedigree