title: Trends in HIV seroprevalence among patients with sexually transmitted diseases in 17 European sentinel networks, 1990-1996. European Study Group.
abstract: OBJECTIVE
  To monitor trends in HIV seroprevalence among sentinel populations of patients with new sexually transmitted disease episodes in 17 networks of 15 European countries.
  
  
  METHODS
  Time trends were estimated by logistic regression for homo-/bisexual men, injecting drug users (IDU) and non-IDU heterosexuals. The networks were included as independent variables to account for different prevalence levels across Europe. Socio-demographic and behavioural data were also included in the model. The interactions of time and each factor in the model were evaluated to determine whether trends differed across networks or population subgroups.
  
  
  RESULTS
  Overall, more than 150,000 sexually transmitted disease episodes were registered in this study. In the European network as a whole, the prevalence decreased significantly among IDU [n = 2619; odds ratio (OR) for annual change, 0.86; 95% confidence interval (CI), 0.80-0.93]. It also decreased among homo-/bisexual men (n = 11,809; OR, 0.92; 95% CI, 0.89-0.94). In both groups, trends did not differ statistically between networks. Among non-IDU heterosexuals (n = 114,024) the prevalence increased significantly (OR, 1.08; 95% CI, 1.04-1.13), especially among women (OR, 1.13) and the time trends differed statistically across networks. A significant increase was observed in four networks, whereas no specific change was detected in the others.
  
  
  CONCLUSIONS
  By applying a standardized protocol, trends in HIV prevalence could be compared across networks and estimated at a more global level. For the validity of HIV trends in such surveys, it is essential to minimize the number of patients not being tested in networks where voluntary testing is required.
authors.affiliation: Scientific Institute of Public Health-Louis Pasteur, Brussels, Belgium.
authors.forename: V
authors.initials: V
authors.lastname: Batter
mesh_terms: D000328:Adult; D001727:Bisexuality; D005060:Europe / Q000453:epidemiology; D005260:Female; D015483:HIV Antibodies / Q000097:blood*; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D015528:HIV Seroprevalence / Q000639:trends*; D015497:HIV-1 / Q000276:immunology*; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D018571:Sentinel Surveillance; D016036:Seroepidemiologic Studies; D012749:Sexually Transmitted Diseases / Q000150:complications*; D015819:Substance Abuse, Intravenous; D013997:Time Factors
chemical_list: D015483:HIV Antibodies