Post-kala-azar dermal leishmaniasis during highly active antiretroviral therapy in an AIDS patient infected with Leishmania infantum.
We report a case of post-kala-azar dermal leishmaniasis (PKDL) in a woman with AIDS which occurred 13 months after a diagnosis of visceral leishmaniasis concomitantly with immunological recovery induced by highly active retroviral therapy. Cytokine pattern at the time of visceral leishmaniasis and PKDL diagnosis was studied and pathogenic implications were discussed.
Ridolfo
A L
AL
Institute of Infectious Diseases and Tropical Medicine, L. Sacco Hospital, University of Milan, Italy.
Gervasoni
C
C
Antinori
S
S
Pizzuto
M
M
Santambrogio
S
S
Trabattoni
D
D
Clerici
M
M
Galli
M
M
D000328:Adult; D000818:Animals; D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D019469:Indinavir / Q000627:therapeutic use; D019259:Lamivudine / Q000627:therapeutic use; D018314:Leishmania infantum; D016773:Leishmaniasis, Cutaneous / Q000209:etiology*; D007898:Leishmaniasis, Visceral / Q000150:complications*; D018119:Stavudine / Q000627:therapeutic use
D019380:Anti-HIV Agents; D019259:Lamivudine; D019469:Indinavir; D018119:Stavudine