title: [Treatment of paraphilia and sexually aggressive impulsive behavior with the LHRH-agonist leuprolide acetate].
abstract: Up to now there are no published results of therapy of paraphilia (Pedophilia, Sadism) and sexual aggressive impulsiveness with LHRH-(luteinizing hormone-releasing hormone) Agonists in the Germanspeaking countries. In this report we describe 11 patients which were treated with the LHRH-Agonist Leuprolide Acetate in a period of 12 months. The patients showed no tendency of sexual aggressive behaviour and reported an evident reduction of penile erection, ejaculation, masturbation, sexual deviant impulsiveness and fantasies. One patient died from suicide. In combination with other treatments LHRH-Agonists seem to be a very promising alternative to cyproterone acetate and its possible carcinogene effects.
authors.affiliation: Abteilung für Sexualforschung, Klinik für Psychiatrie und Psychotherapie, Universität Hamburg.
authors.forename: P
authors.initials: P
authors.lastname: Briken
authors.forename: W
authors.initials: W
authors.lastname: Berner
authors.forename: J
authors.initials: J
authors.lastname: Noldus
authors.forename: E
authors.initials: E
authors.lastname: Nika
authors.forename: U
authors.initials: U
authors.lastname: Michl
mesh_terms: D000328:Adult; D000726:Androgen Antagonists / Q000494:pharmacology / Q000627:therapeutic use*; D017373:Cyproterone Acetate / Q000627:therapeutic use; D005858:Germany; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists*; D006801:Humans; D016729:Leuprolide / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010262:Paraphilic Disorders / Q000097:blood / Q000150:complications / Q000188:drug therapy* / Q000523:psychology / Q000628:therapy; D010554:Personality Disorders / Q000150:complications; D011569:Psychiatric Status Rating Scales; D011613:Psychotherapy; D012448:Sadism / Q000188:drug therapy; D012742:Sex Offenses; D013739:Testosterone / Q000097:blood; D013810:Therapeutic Equivalency; D016896:Treatment Outcome
chemical_list: D000726:Androgen Antagonists; D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D017373:Cyproterone Acetate; D016729:Leuprolide