Medical management of Beauveria bassiana keratitis.
OBJECTIVE
To describe a case of Beauveria bassiana keratitis and to discuss the management of this rare condition.


METHODS
An 82-year-old woman underwent surgical repair of a graft wound dehiscence. Seven months later, shortly after the removal of sutures, the patient developed a fungal keratitis. B. bassiana was identified as the infecting organism. The patient was treated with topical natamycin and oral fluconazole.


RESULTS
Following antifungal therapy, the corneal ulcer was eradicated, but the patient underwent repeat penetrating keratoplasty for decreased vision due to corneal edema. The graft remains clear and visual acuity is substantially improved.


CONCLUSIONS
The medical management of B. bassiana keratitis has previously been unsuccessful. The use of topical natamycin combined with oral fluconazole in the management of this case is discussed.
Kisla
T A
TA
University of Illinois at Chicago Eye Center, Department of Ophthalmology and Visual Sciences, USA.
Cu-Unjieng
A
A
Sigler
L
L
Sugar
J
J
D000368:Aged; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use*; D003320:Corneal Ulcer / Q000188:drug therapy* / Q000382:microbiology; D004359:Drug Therapy, Combination; D015821:Eye Infections, Fungal / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D003904:Mitosporic Fungi / Q000302:isolation & purification*; D009181:Mycoses / Q000188:drug therapy* / Q000382:microbiology; D010866:Natamycin / Q000627:therapeutic use*; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000382:microbiology
D000935:Antifungal Agents; D010866:Natamycin; D015725:Fluconazole