Delayed ischemic neurological deficit of short duration in patients with subarachnoid hemorrhage.
We retrospectively examined the duration of delayed ischemic neurological deficits (DIND) attributed to vasospasm following subarachnoid hemorrhage (SAH) in order to delineate the nature and involved factors. Among 605 patients with SAH, 201 developed DIND, and 137 of these had undergone early aneurysmal obliteration. In these 137, duration of DIND was clearly determined in 67 cases. Hypervolemic therapy was instituted only after the onset of DIND. In the 67 patients, the mean duration of DIND was 5.2 days (ranging from 2 to 13 days); 22 patients had DIND lasting only 2 to 3 days, 26 patients had DIND lasting 4 to 6 days, and in 19, DIND lasted 7 to 13 days. Clinical factors associated with short DIND duration (2 to 3 days) as determined by multivariate analysis included internal carotid artery or middle cerebral artery aneurysm, age under 60, and a good World Federation of Neurological Surgeons grade on admission. No patients developed pulmonary edema from hypervolemic therapy, and the outcomes of all 67 patients were extremely favorable. In SAH patients developing DIND after early aneurysmal surgery, 16% (22 of 137) had a documented brief duration of DIND. We believe DIND rapidly improved and resolved with hypervolemic therapy because antecedent brain damage from SAH or surgical manipulation had been minimal.
Shimoda
M
M
Department of Neurosurgery, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Tominaga
J
J
Atsumi
H
H
Shibata
M
M
Oda
S
S
Oi
S
S
Tsugane
R
R
D005260:Female; D005440:Fluid Therapy; D006801:Humans; D002546:Ischemic Attack, Transient / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012189:Retrospective Studies; D013345:Subarachnoid Hemorrhage / Q000150:complications* / Q000628:therapy