title: The value of ophthalmoscopy in the diagnosis of arterial hypertension in patients with ischemic brain disease.
abstract: Beside dyslipoproteinemia, one of the key risk factors for the onset of brain atherosclerosis, as well as ischemic brain disease (IBD) is arterial hypertension. Significant number of patients is not aware of their hypertension, and a paradoxical blood pressure decrease can occur at the onset of IBD, due to the failure of autoregulation mechanisms. Likewise, valid anamnestic data can not frequently be obtained due to difficulties in communication with patients. Regarding these facts, our hypothesis was that ophthalmoscopy in patients with IBD had the greatest sensitivity in the diagnosis of hypertensive disease, its duration and severity. For that reason, the purpose of this study was to determine the significance of ocular fundus examination in those patients with IBD who were not aware of their hypertension, or the high blood pressure was not registered at the admission. Study comprised 140 IBD patients selected upon the following criteria: ophthalmoscopy was performed by the same ophthalmologist, and IBD was diagnosed according to clinical criteria and by brain computerized tomography. Results of the study demonstrated that 26 (18.6%) patients, although not aware of having hypertensive disease, had grade I hypertonic fundus, 14 (10%) had grade II, and 8 (5.5%) had grade III hypertonic fundus, which indicated the high sensitivity of ophthalmoscopy in the diagnosis of hypertensive disease, as well as its duration and severity. This is particularly important in patients with negative history of hypertension, and also suggests the significance of routine ophthalmoscopy in normotensive patients.
authors.affiliation: Military Medical Academy, Clinic of Neurology, Belgrade.
authors.forename: R
authors.initials: R
authors.lastname: Raicević
authors.forename: P
authors.initials: P
authors.lastname: Aleksić
authors.forename: M
authors.initials: M
authors.lastname: Krgović
authors.forename: L
authors.initials: L
authors.lastname: Marković
authors.forename: D
authors.initials: D
authors.lastname: Tavciovski
authors.forename: B
authors.initials: B
authors.lastname: Rascanin
authors.forename: T
authors.initials: T
authors.lastname: Mrda
authors.forename: B
authors.initials: B
authors.lastname: Gligić
authors.forename: N
authors.initials: N
authors.lastname: Vukotić
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000150:complications*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D012680:Sensitivity and Specificity