title: [Surgical resection of lung cancer in a patient with von Willebrand's disease].
abstract: Von Willebrand's disease (vWD) is one of the most common inherited hemorrhagic disorders, and there have been few reports on major thoracic surgery performed in a patient with the disease. We report a vWD patient who underwent of surgical resection of lung cancer. A 67-year-old gentleman, was diagnosed to have vWD when he was an infant, but he needed no medical treatment. Abnormal shadow in the lung was detected on a mass screening chest X-ray. We performed open biopsy, which proved the shadow to be large cell cancer, and performed right upper lobectomy and lymph node dissection. We used Contact-F, monitoring factor VIII, vWD factor and factor VIII-related antigen, during and after the operation, with a successful result.
authors.affiliation: Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Kosugi
authors.forename: K
authors.initials: K
authors.lastname: Nagai
authors.forename: H
authors.initials: H
authors.lastname: Kawasaki
authors.forename: J
authors.initials: J
authors.lastname: Yoshida
authors.forename: M
authors.initials: M
authors.lastname: Nishimura
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: Y
authors.initials: Y
authors.lastname: Nishiwaki
mesh_terms: D000368:Aged; D018287:Carcinoma, Large Cell / Q000150:complications / Q000601:surgery*; D003894:Deamino Arginine Vasopressin / Q000008:administration & dosage; D006490:Hemostatics / Q000008:administration & dosage; D006801:Humans; D007430:Intraoperative Care; D008175:Lung Neoplasms / Q000150:complications / Q000601:surgery*; D008197:Lymph Node Excision; D008297:Male; D011013:Pneumonectomy; D014842:von Willebrand Diseases / Q000150:complications*
chemical_list: D006490:Hemostatics; D003894:Deamino Arginine Vasopressin