title: Multinodular goiter: the surgical procedure of choice.
abstract: Surgical management of multinodular goiter (MNG) poses an ongoing dilemma between radical resection with its associated complications and partial resection, which carries the risk of recurrence and increased morbidity and difficulty for rethyroidectomy. This study was designed to evaluate the recurrence rate and need for reoperation in a carefully selected population of MNG patients, after nontotal thyroidectomy. The study addressed a highly selected population of patients who were treated and thoroughly evaluated at one surgical department for several years. We analyzed the recurrence rate of MNG in 124 patients. The follow-up duration extended from 6 to 516 months (mean 93 months). The general recurrence rate for all nontotal bilateral thyroidectomies was 21% (21/100 patients), increasing from 13.4% to 60% according to the extent of resection. The average time for recurrence was 105 months (8.75 years). Among the patients with recurrent MNG, only 4 (4% of the patients with nontotal bilateral thyroidectomy) required secondary surgical interventions with no resultant morbidity. In our series of very highly selected patients, the recurrence rate for nontotal thyroidectomy was high (21%); however, the need for secondary surgical intervention was low (4%). Thus nontotal thyroidectomy for MNG is legitimate. However, we suggest that the surgical procedure of choice be tailored according to the severity of the disease and the patient's general condition.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Carmel Medical Center, Hiafa, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Cohen-Kerem
authors.forename: P
authors.initials: P
authors.lastname: Schachter
authors.forename: M
authors.initials: M
authors.lastname: Sheinfeld
authors.forename: E
authors.initials: E
authors.lastname: Baron
authors.forename: O
authors.initials: O
authors.lastname: Cohen
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006042:Goiter / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012086:Reoperation; D013965:Thyroidectomy / Q000379:methods*; D016896:Treatment Outcome