title: Influence of associated anomalies on the management of oesophageal atresia.
abstract: Associated congenital abnormalities occur in over 50% of infants with oesophageal atresia. Many of them influence the way in which the oesophageal atresia is managed and therefore should be detected as soon as possible after birth. Early recognition of those with no prospect of long-term survival (e.g. Trisomy 18, bilateral renal agenesis) will avoid unnecessary surgery to the oesophagus. About 12% of oesophageal atresia infants will have no surgery performed. This paper presents a protocol for the initial investigation and management of associated anomalies in oesophageal atresia, based on an experience of 670 infants treated at the Royal Children's Hospital, Melbourne, Pre-operative detection of associated anomalies of oesophageal atresia requires clinical examination, pre-operative renal ultrasound (if the child has not passed urine), and an echocardiograph of the heart to exclude duct-dependent lesions. If there is clinical suspicion of a major chromosomal abnormality, surgery should be deferred until chromosomal analysis has been completed.
authors.affiliation: Royal Children's Hospital, Parkville, Australia.
authors.forename: S W
authors.initials: SW
authors.lastname: Beasley
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics / Q000401:mortality / Q000601:surgery*; D004933:Esophageal Atresia / Q000235:genetics / Q000401:mortality / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D011379:Prognosis; D015996:Survival Rate; D014138:Tracheoesophageal Fistula / Q000235:genetics / Q000401:mortality / Q000601:surgery; D014463:Ultrasonography