title: Histomorphologic findings on human bone samples six months after bone augmentation of the maxillary sinus with Algipore.
abstract: Sinus grafting, a popular and standard treatment for maxillary atrophy, uses a variety of grafting materials. In this study, specimens obtained 6 months after sinus grafting with Algipore were evaluated under light microscopy and showed osseoformation, xenograft degradation, and bone ingrowth into particles. Osteoblastic cells were embedded in the intracorpuscular bone matrix, which indicated that xenograft particles are an osseoconductive scaffold and stimulate matrix deposition. Acute inflammatory responses after insertion of Algipore did not occur. Particles were degraded during physiologic bone remodeling, and newly formed bone gradually replaced resorbed biomaterial.
authors.affiliation: University Clinic of Oral and Maxillofacial Surgery, General Hospital, University of Vienna.
authors.forename: C
authors.initials: C
authors.lastname: Schopper
authors.forename: D
authors.initials: D
authors.lastname: Moser
authors.forename: F
authors.initials: F
authors.lastname: Wanschitz
authors.forename: F
authors.initials: F
authors.lastname: Watzinger
authors.forename: G
authors.initials: G
authors.lastname: Lagogiannis
authors.forename: E
authors.initials: E
authors.lastname: Spassova
authors.forename: R
authors.initials: R
authors.lastname: Ewers
mesh_terms: D018786:Bone Substitutes / Q000627:therapeutic use*; D001842:Bone and Bones / Q000473:pathology*; D003758:Dental Implantation, Endosseous; D017886:Durapatite / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008443:Maxillary Sinus / Q000473:pathology* / Q000601:surgery*; D008875:Middle Aged; D016348:Osseointegration; D019340:Osteotomy, Le Fort / Q000379:methods; D013997:Time Factors
chemical_list: D018786:Bone Substitutes; D017886:Durapatite