title: New taxanes with an opened oxetane ring from the roots of Taxus mairei.
abstract: Two novel taxoids, taxumairols N (1) and O (2), have been isolated from extracts of the roots of Taxus mairei. The structures of 1 and 2 were identified as 7beta,9alpha,10beta,13alpha-tetraacetoxy-2alp ha, 4alpha,5alpha,20-tetrahydroxytax-11-ene and 7beta,9alpha,10beta, 13alpha-tetraacetoxy-1beta,2alpha,4alpha,5alp ha, 20-pentahydroxytax-11-ene on the basis of 1D and 2D NMR techniques including COSY, HMQC, HMBC, and NOESY experiments.
authors.affiliation: Institute of Marine Resources, National Sun Yat-sen University, 70 Lien-Hai Road, Kaohsiung, Taiwan, Republic of China. ycshen@mail.nsysu.edu.tw
authors.forename: Y C
authors.initials: YC
authors.lastname: Shen
authors.forename: K L
authors.initials: KL
authors.lastname: Lo
authors.forename: C Y
authors.initials: CY
authors.lastname: Chen
authors.forename: Y H
authors.initials: YH
authors.lastname: Kuo
authors.forename: M C
authors.initials: MC
authors.lastname: Hung
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D017239:Paclitaxel / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D043823:Taxoids; D020946:Taxus / Q000737:chemistry*
chemical_list: D043823:Taxoids; C411303:taxumairol N; C411304:taxumairol O; D017239:Paclitaxel