title: Preparation of new chiral borane-protected P,N-ferrocenyl ligands via a methoxy directed ortho-lithiation.
abstract: We have shown that the readily prepared (ferrocenyl)benzylic methyl ethers of type 1 can be ortho-metalated with tert-BuLi with high diastereoselectivity. This reaction has been used to prepare new borane-protected P,N-substituted ferrocenes of type 2 in high diastereomeric and enantiomeric purity. The chiral heterocyclic aminophosphines 2 may be of interest as chelating ligands for asymmetric metal catalysis.
authors.affiliation: Department of Chemistry, University of Munich, Munich, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Lotz
authors.forename: T
authors.initials: T
authors.lastname: Ireland
authors.forename: K
authors.initials: K
authors.lastname: Tappe
authors.forename: P
authors.initials: P
authors.lastname: Knochel