title: Synthesis of FF-MAS from lithocholic acid.
abstract: An effective synthesis of 4,4 dimethyl-cholest-8,14,24-trien-3beta-ol (FF-MAS) from lithocholic acid is described, utilising a double oxidation and regioselective Wittig reaction as key steps.
authors.affiliation: Novo Nordisk A/S, Målov, Denmark.
authors.forename: A
authors.initials: A
authors.lastname: Murray
authors.forename: F C
authors.initials: FC
authors.lastname: Grønvald
authors.forename: J K
authors.initials: JK
authors.lastname: Nielsen
authors.forename: P
authors.initials: P
authors.lastname: Faarup
mesh_terms: D001671:Biochemistry / Q000379:methods; D002775:Cholestadienols / Q000138:chemical synthesis*; D008095:Lithocholic Acid / Q000737:chemistry
chemical_list: C114832:4,4-dimethyl-5alpha-cholest-8,14,24-trien-3-ol; D002775:Cholestadienols; D008095:Lithocholic Acid