Self-injection ictal SPECT during partial seizures.
The authors compared ictal SPECT injection performed by medical personnel with self-injection ictal SPECT in six patients with refractory temporal lobe epilepsy. Self-injection was safe and started faster. Self-injection subtraction ictal SPECT coregistered to MRI (SISCOM) was localizing in three patients who had a complex partial seizure, but only one of three patients who had a simple partial seizure, which may limit its usefulness in clinical practice. The localizing information of self-injection was better in three patients, and obviated the need for depth-EEG studies in one patient.
Van Paesschen
W
W
Department of Neurology, University Hospital Gasthuisberg, Leuven, Belgium.
Dupont
P
P
Van Heerden
B
B
Vanbilloen
H
H
Mesotten
L
L
Maes
A
A
Van Driel
G
G
Mortelmans
L
L
D000328:Adult; D001931:Brain Mapping; D003545:Cysteine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004833:Epilepsy, Temporal Lobe / Q000000981:diagnostic imaging* / Q000601:surgery; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds / Q000008:administration & dosage*; D019275:Radiopharmaceuticals / Q000008:administration & dosage*; D012646:Self Administration; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation*
D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C059659:technetium Tc 99m bicisate; D003545:Cysteine