Toward quantitative genetic analysis of host and parasite traits in the manifestations of Plasmodium falciparum malaria.
The complex human and parasite determinants that influence disease severity in Plasmodium falciparum malaria reflect thousands of years of selective pressure. Emerging genetic and genomic resources offer the prospect of unraveling interactions of these determinants.
Taylor
J G
JG
Malaria Genetics Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-0425, USA.
Ferdig
M T
MT
Su
X Z
XZ
Wellems
T E
TE
D000818:Animals; D006790:Host-Parasite Interactions / Q000235:genetics*; D006801:Humans; D016778:Malaria, Falciparum / Q000235:genetics* / Q000503:physiopathology; D010963:Plasmodium falciparum / Q000235:genetics*; D011110:Polymorphism, Genetic; D012641:Selection, Genetic