title: The stability of remifentanil hydrochloride and propofol mixtures in polypropylene syringes and polyvinylchloride bags at 22 degrees-24 degrees C.
abstract: Remifentanil and propofol mixtures may be prepared extemporaneously. This study demonstrated that such mixtures are stable for 0 to 36 h, depending on relative concentrations of the drugs and the storage container used. The most stable mixtures were stored in syringes and used large concentrations of the two drugs.
authors.affiliation: Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia 30602-2352, USA. Jstewart@rx.uga.edu
authors.forename: J T
authors.initials: JT
authors.lastname: Stewart
authors.forename: F W
authors.initials: FW
authors.lastname: Warren
authors.forename: F C
authors.initials: FC
authors.lastname: Maddox
authors.forename: K
authors.initials: K
authors.lastname: Viswanathan
authors.forename: J L
authors.initials: JL
authors.lastname: Fox
mesh_terms: D018686:Anesthetics, Intravenous / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004338:Drug Combinations; D004349:Drug Packaging; D004355:Drug Stability; D010880:Piperidines / Q000737:chemistry*; D011126:Polypropylenes; D011143:Polyvinyl Chloride; D015742:Propofol / Q000737:chemistry*; D000077208:Remifentanil; D013594:Syringes; D013696:Temperature
chemical_list: D018686:Anesthetics, Intravenous; D004338:Drug Combinations; D010880:Piperidines; D011126:Polypropylenes; D011143:Polyvinyl Chloride; D000077208:Remifentanil; D015742:Propofol