Control of division gene expression in Escherichia coli.
Duplication of the Escherichia coli bacterial cell culminates in the formation of a division septum that splits the progenitor cell into two identical daughter cells. Invagination of the cell envelope is brought about by the co-ordinated interplay of a family of septation-specific proteins that act locally at mid-cell at a specific time in the cell cycle. The majority of the genes known to be required for septum formation are found within the large mra cluster located at 2 min on the E. coli genetic map (nucleotides 89552-107474). Examination of the controls exerted on the mra operon shows that E. coli uses an extraordinary range of strategies to co-ordinate the expression of the cell division genes with respect to each other and to the cell cycle.
Dewar
S J
SJ
Department of Biological Sciences, Heriot Watt University, EH14 4AS, Edinburgh, UK. s.j.dewar@hw.ac.uk
Dorazi
R
R
D001426:Bacterial Proteins / Q000235:genetics; D002455:Cell Division / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics* / Q000254:growth & development; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial / Q000235:genetics; D008018:Life Cycle Stages; D009876:Operon; D011401:Promoter Regions, Genetic; D014158:Transcription, Genetic
D001426:Bacterial Proteins