title: Angiosarcoma of the scalp and face: failure of an interferon alpha treatment.
abstract: Angiosarcoma of the scalp and face is a rare malignant endothelial tumor arising in elderly people. Treatment is disappointing and prognosis remains poor. We report two cases of angiosarcoma of the scalp and face relapsing after classical therapy with surgery and radiotherapy and treated with interferon alpha. The tolerance was poor and the disease progressed 2 and 5 months after the onset of the treatment. When used alone, interferon alpha does not appear as an effective treatment in this kind of angiosarcoma.
authors.affiliation: Service de Dermatologie, Hôpital Caremeau, CHU de Nîmes, 30029 Nîmes Cedex 9, France.
authors.forename: B
authors.initials: B
authors.lastname: Guillot
authors.forename: N
authors.initials: N
authors.lastname: Raison-Peyron
authors.forename: M
authors.initials: M
authors.lastname: Acevedo
authors.forename: L
authors.initials: L
authors.lastname: Meunier
authors.forename: M
authors.initials: M
authors.lastname: Dandurand
authors.forename: J
authors.initials: J
authors.lastname: Meynadier
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001706:Biopsy; D005153:Facial Neoplasms / Q000188:drug therapy* / Q000473:pathology; D017809:Fatal Outcome; D006394:Hemangiosarcoma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007273:Injections, Intramuscular; D016898:Interferon-alpha / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012535:Scalp / Q000473:pathology*; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D016898:Interferon-alpha