Staminolactones A and B and norstaminol A: three highly oxygenated staminane-type diterpenes from Orthosiphon stamineus.
[formula: see text] Staminolactones A (1) and B (2) and norstaminol A (3), three highly oxygenated staminane-type diterpenes having mild cytotoxic activities against highly liver-metastatic colon 26-L5 carcinoma cells, were isolated from the aerial part of the Vietnamese medicinal plant Orthosiphon stamineus (Lamiaceae). Their structures were elucidated on the basis of the extensive spectral analyses.
Stampoulis
P
P
Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Japan.
Tezuka
Y
Y
Banskota
A H
AH
Tran
K Q
KQ
Saiki
I
I
Kadota
S
S
D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology; D003110:Colonic Neoplasms / Q000473:pathology; D004224:Diterpenes / Q000737:chemistry* / Q000494:pharmacology; D019686:Lamiaceae / Q000737:chemistry*; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry; D013057:Spectrum Analysis; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D004224:Diterpenes; C409105:norstaminol A; C409104:staminolactone A; C409103:staminolactone B; D010100:Oxygen