title: Paragonimiasis westermani with multifocal lesions in lungs and skin.
abstract: We report a case of Paragonimus westermani infection with a reticulonodular lesion in the right lung, left pleural effusion, and a mobile subcutaneous mass. Analyses of pleural effusion and bronchoalveolar lavage fluid (BALF) showed marked eosinophilia and high levels of eosinophil cationic protein and interleukin (IL)-5. Transbronchial lung biopsy revealed the presence of pneumonia with mild eosinophilic infiltration but remarkable lymphocytic infiltration. In this patient, high IL-5 levels in both BALF and pleural effusion could explain the remarkable eosinophilia.
authors.affiliation: National Sanatorium Miyazakihigashi Hospital, Miyazaki.
authors.forename: J
authors.initials: J
authors.lastname: Ashitani
authors.forename: K
authors.initials: K
authors.lastname: Kumamoto
authors.forename: S
authors.initials: S
authors.lastname: Matsukura
mesh_terms: D000368:Aged; D001798:Blood Proteins / Q000378:metabolism; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry; D047091:Eosinophil Granule Proteins; D004802:Eosinophilia / Q000209:etiology; D005260:Female; D006801:Humans; D015848:Interleukin-5 / Q000378:metabolism; D017563:Lung Diseases, Interstitial / Q000209:etiology; D008174:Lung Diseases, Parasitic / Q000175:diagnosis*; D010237:Paragonimiasis / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D010996:Pleural Effusion / Q000378:metabolism; D012260:Ribonucleases; D012876:Skin Diseases, Parasitic / Q000175:diagnosis*
chemical_list: D001798:Blood Proteins; D047091:Eosinophil Granule Proteins; D015848:Interleukin-5; D012260:Ribonucleases