Group-specific component (Gc) subtypes in the Chinese population of Hong Kong.
The distribution of Gc subtypes in a sample of the Chinese population of Hong Kong was studied using isoelectric focusing followed by immunofixation. A sensitive modification of this technique is described. Nine distinct phenotypes were observed which appear to result from the three common alleles Gc1F, Gc1S, and Gc2, which are found in most populations. The respective gene frequencies were 0.494, 0.258, and 0.247. In addition, two rare phenotypes were observed which appear to be due to a rare allele tentatively identified as Gc2C2.
Kwok
K Y
KY
Institute of Medical and Health Care, Hong Kong Polytechnic, Hung Hom, Kowloon, Hong Kong.
Lewis
W H
WH
D000328:Adult; D001801:Blood Stains; D005787:Gene Frequency; D006723:Hong Kong / Q000208:ethnology; D006801:Humans; D007525:Isoelectric Focusing; D008297:Male; D010641:Phenotype; D014809:Vitamin D-Binding Protein / Q000145:classification / Q000235:genetics*
D014809:Vitamin D-Binding Protein