title: Seminoma with cutaneous metastases in a dog.
abstract: A 10-year-old Great Pyrenees was presented for anorexia and weight loss. On physical examination, the dog was emaciated and showed a large ulcerated lesion on the right lower lip in addition to an enlarged right testicle. Fine-needle aspiration biopsy of the testicle and surgical biopsy of the lip lesion were performed; the histopathological report was consistent with metastatic seminoma. The diagnostic and therapeutic approach in this unusual metastatic seminoma is presented and compared to the previous literature. A multimodality therapy consisting of surgery and chemotherapy is proposed for the clinical management of metastatic seminoma in dogs.
authors.affiliation: Department of Pathology and Experimental Veterinary Pathology, National Cancer Institute Regina Elena of Rome, Italy.
authors.forename: E P
authors.initials: EP
authors.lastname: Spugnini
authors.forename: A
authors.initials: A
authors.lastname: Bartolazzi
authors.forename: D
authors.initials: D
authors.lastname: Ruslander
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D004285:Dogs; D008048:Lip Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D008297:Male; D018239:Seminoma / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D012878:Skin Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*