title: Intestinal atresia and stenosis: a retrospective analysis of presentation, morbidity and mortality in Zaria, Nigeria.
abstract: Over a period of 19 years 22 children with intestinal atresia and stenosis were managed at the Ahmadu Bello University Teaching Hospital Zaria. The condition ranks as the fourth most common cause of neonatal intestinal obstruction after anorectal malformation, Hirschsprung's disease and strangulated inguinal hernia at the hospital. Three patients had duodenal atresia, 18 had jejunoileal involvement (atresia 15, stenosis 3) and one colonic atresia. The median age at presentation to the surgeon was 6 days (range 1 day-2 years). The common features were bilious vomiting and abdominal distension, the latter being more common in patients with lower atresia. Non-passage of meconium in the first 24 hours of birth occurred in 11 patients; mostly in those with lower jejunal, ileal and colonic involvement. Eight patients had associated anomalies, 5 of them with ileal atresia or stenosis. Diagnostic investigation was mainly plain abdominal radiography showing double-bubble shadow in duodenal atresia and varying degrees of air-fluid levels in other atresias. Contrast studies were not employed for diagnosis in any patient. The patients with duodenal atresia and had duodenoduodenostomy and duodenojejunostomy respectively while the jejunoileal atresia and stenosis were treated by resection and anastomosis. One patient with ileal atresia associated with total colonic Hirschsprung's disease and extensive atresia from terminal ileum down to descending colon had ileostomy. Postoperatively, 7 patients had infections of varying degrees and 3 anastomotic dehiscence. Mortality was 9 (41%) due mostly to septic complications and prematurity. While the survival of children with intestinal atresia and stenosis has improved over the years in developed countries, ours is still low (59%) due to late presentation and lack of neonatal intensive care facilities.
authors.affiliation: Department of Surgery, Ahmadu Bello University Teaching Hospital Zaria, Nigeria.
authors.forename: E A
authors.initials: EA
authors.lastname: Ameh
authors.forename: P T
authors.initials: PT
authors.lastname: Nmadu
mesh_terms: D002675:Child, Preschool; D004385:Duodenostomy; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007231:Infant, Newborn; D007409:Intestinal Atresia / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D007415:Intestinal Obstruction / Q000209:etiology; D007582:Jejunostomy; D008297:Male; D009017:Morbidity; D009549:Nigeria / Q000453:epidemiology; D012189:Retrospective Studies; D014504:Urban Health