title: [L-dopa effective parkinsonism appeared after shunt revision of the aqueductal stenosis: report of two cases].
abstract: We present a two cases of parkinsonism that appeared after shunt revision in obstructive hydrocephalus patients. Case 1 was a 59-year-old man and case 2 was a 32-year-old woman. Parkinsonism appeared in both cases after 3 or 4 shunt revisions within a period of three months. Treatment with bromocriptine, amantadine and L-dops had no effect, but the parkinsonism dramatically improved with administration of L-dopa. It was thought that repeated dilatation and collapse of the third ventricle in a short period of time might have caused concussion of the nigrostriatal pathway, resulting in reversible function loss of the nigrostriatal pathway.
authors.affiliation: Department of Neurosurgery, Miyazaki Prefectural Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ochiai
authors.forename: Y
authors.initials: Y
authors.lastname: Yamakawa
authors.forename: S
authors.initials: S
authors.lastname: Miyata
authors.forename: T
authors.initials: T
authors.lastname: Kawasoe
mesh_terms: D000328:Adult; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D002535:Cerebral Aqueduct / Q000473:pathology*; D003251:Constriction, Pathologic / Q000150:complications; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000601:surgery*; D007980:Levodopa / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy* / Q000209:etiology; D011183:Postoperative Complications / Q000188:drug therapy* / Q000209:etiology; D017287:Ventriculoperitoneal Shunt
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa