[Diagnosis of the hibernating myocardium in early stages of heart failure in patients with coronary heart disease].
The paper presents current views on ischemia-reperfusion and mechanisms of its development. Their role in the development of the hibernating myocardium is shown. Possible clinical manifestations of these conditions and currently available diagnostic techniques are assessed. The purpose of the study was to detect the hibernating myocardium in patients with coronary heart disease (CHD) and arterial hypertension (AH). The study enrolled 13 patients with CHD and AH. Myocardial biventricular scintigraphy was conducted in patients before treatment and during acute coronarolytic test. Prior to treatment, all the patients were found to have reversible asynergy, left and right ventricular myocardial hypo- and dyskinesia caused by the hibernating myocardium. The drug test revealed better segmental contractility than the baseline one due to the fact that the function of asynergic segments recovered and fraction ejection increased. The findings suggest that the hibernating myocardium is diagnosed in patients with CHD and AH without myocardial infarction, which is of importance in determining treatment policy and prognosis in these patients.
Fomina
I G
IG
Georgadze
Z A
ZA
Gaĭdamakina
N E
NE
Galanina
N A
NA
D003331:Coronary Vessels / Q000503:physiopathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology*; D017202:Myocardial Ischemia / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology*; D017682:Myocardial Stunning / Q000150:complications / Q000175:diagnosis*; D012720:Severity of Illness Index; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology