Raised maternal serum inhibin A concentration at 10 to 14 weeks of gestation is associated with pre-eclampsia.
Maternal serum inhibin A and free beta human chorionic gonadotrophin (beta-hCG) were measured in 759 chromosomally normal, pregnant women at 10-14 weeks of gestation. There were nine who subsequently developed pre-eclampsia and in these women the maternal serum inhibin A concentration was significantly higher than in the normotensive controls.
Sebire
N J
NJ
Harris Birthright Research Centre, Kings College Hospital, London, UK.
Roberts
L
L
Noble
P
P
Wallace
E
E
Nicolaides
K H
KH
D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000097:blood*; D006801:Humans; D007265:Inhibins / Q000097:blood*; D011225:Pre-Eclampsia / Q000175:diagnosis*; D011247:Pregnancy; D011261:Pregnancy Trimester, First / Q000097:blood; D012307:Risk Factors
D015415:Biomarkers; D007987:Gonadotropin-Releasing Hormone; D007265:Inhibins