title: Identification of monozygotic twins that are concordant for preeclampsia.
abstract: Preeclampsia is thought to be discordant in monozygotic twins. While recruiting for a genetic study into preeclampsia, we identified 4 sets of twins and a triplet gestation; all were monozygous on deoxyribonucleic acid "fingerprinting." Two twins were concordant for preeclampsia, and 2 of the triplets had pregnancy-induced hypertension, although only 1 of them had proteinuria. Hence we confirm the existence of monozygotic twins that are concordant for preeclampsia.
authors.affiliation: Clinical Pharmacology Unit, Department of Medicine, University of Cambridge Clinical School, UK. km022@medschl.cam.ac.uk
authors.forename: K M
authors.initials: KM
authors.lastname: O'shaughnessy
authors.forename: F
authors.initials: F
authors.lastname: Ferraro
authors.forename: B
authors.initials: B
authors.lastname: Fu
authors.forename: S
authors.initials: S
authors.lastname: Downing
authors.forename: N H
authors.initials: NH
authors.lastname: Morris
mesh_terms: D004200:Diseases in Twins; D005260:Female; D005838:Genotype; D006801:Humans; D011225:Pre-Eclampsia / Q000235:genetics*; D011247:Pregnancy; D014310:Triplets; D014430:Twins, Monozygotic