A cardiovascular EST repertoire: progress and promise for understanding cardiovascular disease.
The application of expressed sequence tag (EST) technology has proven to be an effective tool for gene discovery and the generation of gene expression profiles. The generation of an EST resource for the cardiovascular system has revealed significant insights into the changes in gene expression that guide heart development and disease. Furthermore, an important genetic resource has been developed for cardiovascular biology that is valuable for data mining and disease gene discovery.
Dempsey
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The Cardiovascular Genome Unit, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Ton
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Liew
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D000818:Animals; D002318:Cardiovascular Diseases / Q000235:genetics*; D002319:Cardiovascular System; D020224:Expressed Sequence Tags; D006801:Humans