title: Scintimammographic findings of in situ ductal breast carcinoma in a double-phase study with Tc-99m(V) DMSA and Tc-99m MIBI value of Tc-99m(V) DMSA.
abstract: The authors present a case of in situ ductal carcinoma of the breast (DCIS) with no associated mass in a 46-year-old woman examined with Tc-99m MIBI and Tc-99m(V) DMSA scans, which were acquired in separate sessions 10 minutes and 60 minutes after injection. Histologic analysis revealed a small (<1 cm) infiltrating ductal carcinoma located within the DCIS. Mammography showed a cluster of microcalcifications on a very dense parenchymal background. Tc-99m(V) DMSA was characterized as positive for DCIS, especially in the delayed image. Tc-99m MIBI failed to identify the lesions previously noted. In conclusion, Tc-99m(V) DMSA scintimammography seems to have an advantage and could improve the detection of nonpalpable in situ breast carcinomas.
authors.affiliation: Department of Nuclear Medicine, Alexandra Hospital, University of Athens, Greece.
authors.forename: V
authors.initials: V
authors.lastname: Papantoniou
authors.forename: M
authors.initials: M
authors.lastname: Sotiropoulou
authors.forename: E
authors.initials: E
authors.lastname: Stipsaneli
authors.forename: A
authors.initials: A
authors.lastname: Louvrou
authors.forename: H
authors.initials: H
authors.lastname: Feda
authors.forename: J
authors.initials: J
authors.lastname: Christodoulidou
authors.forename: G
authors.initials: G
authors.lastname: Pampouras
authors.forename: C
authors.initials: C
authors.lastname: Zerva
authors.forename: A
authors.initials: A
authors.lastname: Keramopoulos
authors.forename: S
authors.initials: S
authors.lastname: Michalas
mesh_terms: D001940:Breast / Q000000981:diagnostic imaging* / Q000473:pathology; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging; D002278:Carcinoma in Situ / Q000000981:diagnostic imaging* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D017256:Technetium Tc 99m Sestamibi
chemical_list: D019275:Radiopharmaceuticals; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D017256:Technetium Tc 99m Sestamibi