[The effect of anesthesia on lipid peroxidation, the antioxidant system and lipid metabolism during cesarean section in parturients with severe forms of late gestosis].
Forty-three parturients with severe late gestosis were subjected to cesarean section under endotracheal general anesthesia (EGA) (23 pts) and combined epidural anesthesia (CEA) (20 pts). Lipid peroxidation (LPO), antioxidant system (AOS), and lipid metabolism parameters were evaluated at various stages of anesthesia and operation. EN involved a marked increase in LPO, suppressed the activities of vitamin and enzymatic components of AOS, and disturbed lipid metabolism, while CEA was associated with a less pronounced intensification of LPO, slight suppression of AOS, and slight changes in lipid metabolism, which makes this types of analgesia preferable.
Lynev
S N
SN
Kengerli
G S
GS
D000208:Acute Disease; D000328:Adult; D000770:Anesthesia, Endotracheal / Q000379:methods; D000767:Anesthesia, Epidural / Q000379:methods; D000773:Anesthesia, Obstetrical / Q000379:methods; D000975:Antioxidants / Q000378:metabolism*; D002585:Cesarean Section; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects*; D008055:Lipids / Q000097:blood*; D011225:Pre-Eclampsia / Q000097:blood* / Q000601:surgery; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third
D000975:Antioxidants; D008055:Lipids