title: Staminolactones A and B and norstaminol A: three highly oxygenated staminane-type diterpenes from Orthosiphon stamineus.
abstract: [formula: see text] Staminolactones A (1) and B (2) and norstaminol A (3), three highly oxygenated staminane-type diterpenes having mild cytotoxic activities against highly liver-metastatic colon 26-L5 carcinoma cells, were isolated from the aerial part of the Vietnamese medicinal plant Orthosiphon stamineus (Lamiaceae). Their structures were elucidated on the basis of the extensive spectral analyses.
authors.affiliation: Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Japan.
authors.forename: P
authors.initials: P
authors.lastname: Stampoulis
authors.forename: Y
authors.initials: Y
authors.lastname: Tezuka
authors.forename: A H
authors.initials: AH
authors.lastname: Banskota
authors.forename: K Q
authors.initials: KQ
authors.lastname: Tran
authors.forename: I
authors.initials: I
authors.lastname: Saiki
authors.forename: S
authors.initials: S
authors.lastname: Kadota
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology; D003110:Colonic Neoplasms / Q000473:pathology; D004224:Diterpenes / Q000737:chemistry* / Q000494:pharmacology; D019686:Lamiaceae / Q000737:chemistry*; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry; D013057:Spectrum Analysis; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D004224:Diterpenes; C409105:norstaminol A; C409104:staminolactone A; C409103:staminolactone B; D010100:Oxygen