A pseudolymphomatous skin reaction secondary to flucloxacillin.
We report the first case of a pseudolymphomatous skin reaction precipitated by flucloxacillin. Skin histology was suggestive of a cutaneous lymphoma, and DNA analysis by single stranded conformational polymorphism (SSCP) demonstrated T-cell receptor gamma gene monoclonality. Withdrawal of flucloxacillin led to immediate clinical improvement and gradual resolution of skin rash and lymph nodes.
Melzer
M
M
Department of Microbiology, St Thomas' Hospital, London, UK.
Keane
F M
FM
Eykyn
S J
SJ
Breathnach
S M
SM
D000368:Aged; D005436:Floxacillin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010406:Penicillins / Q000009:adverse effects*; D019310:Pseudolymphoma / Q000139:chemically induced*; D012871:Skin Diseases / Q000139:chemically induced*
D010406:Penicillins; D005436:Floxacillin