A practical and facile route for the preparation of 18-norandrostan-17-ones from androstan-17-ones using SmI(2)-promoted cyclization and dehydroxylation.
Jiang
X
X
Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Wang
C
C
Hu
Y
Y
Hu
H
H
Covey
D F
DF
D000731:Androstanes / Q000737:chemistry*; D003500:Cyclization; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009635:Norandrostanes / Q000138:chemical synthesis* / Q000737:chemistry
D000731:Androstanes; D009635:Norandrostanes; C018454:androstan-17-one