title: Identification and total synthesis of a novel dimethylated fatty acid from the Caribbean sponge Calyx podatypa.
abstract: The dimethylated fatty acid 9,13-dimethyltetradecanoic acid was identified for the first time in nature in the Caribbean sponge Calyx podatypa where it occurs together with the rare 10, 13-dimethyltetradecanoic acid. The characterization of the novel compound was accomplished using GC-MS, pyrrolidide derivatization, and a five-step total synthesis starting with 8-bromooctanoic acid. The first racemic total synthesis for the rare 10, 13-dimethyltetradecanoic acid is also described.
authors.affiliation: Department of Chemistry, University of Puerto Rico, P.O. Box 23346, San Juan, Puerto Rico 00931, USA. ncarball@upracd.upr.clu.edu
authors.forename: N M
authors.initials: NM
authors.lastname: Carballeira
authors.forename: M
authors.initials: M
authors.lastname: Pagán
mesh_terms: D000818:Animals; D002849:Chromatography, Gas; D005227:Fatty Acids / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D011161:Porifera / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: C411203:10,13-dimethyltetradecanoic acid; C411202:9,13-dimethyltetradecanoic acid; D005227:Fatty Acids