title: Superoxide-scavenging and prolyl endopeptidase inhibitory activities of Bangladeshi indigenous medicinal plants.
abstract: The superoxide-scavenging and prolyl endopeptidase (PEP) inhibitory activities of 15 different kinds of Bangladeshi medicinal plants were evaluated. Methanol extraction was performed for the screening tests. Swertia chirata, Emblica officinalis, Zingiber officinale and Myristica malabarica were screened as superoxide-scavenging samples. Similarly, E. officinalis was identified as one of the strongest PEP inhibitory samples. The 50% (O2-)-scavenging and PEP-inhibitory concentrations from E. officinalis methanol extracts were found to be 13.17 and 26.10 microg/ml, respectively.
authors.affiliation: The United Graduate School of Agricultural Science, Gifu University, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Khanom
authors.forename: H
authors.initials: H
authors.lastname: Kayahara
authors.forename: K
authors.initials: K
authors.lastname: Tadasa
mesh_terms: D001459:Bangladesh; D003574:Cytochrome c Group / Q000378:metabolism; D016166:Free Radical Scavengers / Q000378:metabolism*; D007202:Indicators and Reagents; D009580:Nitroblue Tetrazolium; D010936:Plant Extracts; D010946:Plants, Medicinal / Q000378:metabolism*; D000085822:Prolyl Oligopeptidases; D012697:Serine Endopeptidases / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism*
chemical_list: D003574:Cytochrome c Group; D016166:Free Radical Scavengers; D007202:Indicators and Reagents; D010936:Plant Extracts; D013481:Superoxides; D009580:Nitroblue Tetrazolium; D012697:Serine Endopeptidases; D000085822:Prolyl Oligopeptidases