Comparison of quantitations of viral load in varicella and zoster.
The pathogenesis of varicella and zoster and the effects of antiviral treatment were investigated using real-time PCR for varicella-zoster virus (VZV) DNA in skin lesions and peripheral blood. A higher occurrence of viremic VZV DNA was observed in varicella than in zoster. Acyclovir treatment resulted in marked suppression of viremia in varicella.
Kimura
H
H
Department of Pediatrics, Nagoya University School of Medicine, Nagoya, Japan. hkimura@med.nagoya-u.ac.jp
Kido
S
S
Ozaki
T
T
Tanaka
N
N
Ito
Y
Y
Williams
R K
RK
Morishima
T
T
D000212:Acyclovir / Q000627:therapeutic use; D000293:Adolescent; D002644:Chickenpox / Q000097:blood / Q000188:drug therapy / Q000473:pathology / Q000821:virology*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D012867:Skin / Q000821:virology; D019562:Viral Load
D000212:Acyclovir