title: 3D assessment of myocardial perfusion parameter combined with 3D reconstructed coronary artery tree from digital coronary angiograms.
abstract: In patients with coronary artery disease coronary angiography plays an important role in the clinical decision-making process. However, it has been recognized that no simple relation exists between the visually or quantitatively evaluated severity of coronary artery stenoses and its effects on regional myocardial perfusion. This paper describes for the first time the development and application of a 3D technique that visualizes and quantifies regional myocardial perfusion parameters from biplane coronary angiograms by using the impulse response analysis technique. The 3D reconstructed coronary tree is automatically superimposed on the 3D perfusion image to generate and visualize an 'integrated' 3D image. The preliminary results in patients with critical coronary artery stenoses indicate that our combined 3D fusion image provides flow information from the major coronary arteries. This 3D fusion image may provide useful information in the management of patients with coronary artery disease.
authors.affiliation: Medizinische Universitätsklinik Freiburg, Abteilung Innere Medizin III, Kardiologie und Angiologie, Germany. schindler@mm31.ukl.uni-freiburg.de
authors.forename: T H
authors.initials: TH
authors.lastname: Schindler
authors.forename: N
authors.initials: N
authors.lastname: Magosaki
authors.forename: M
authors.initials: M
authors.lastname: Jeserich
authors.forename: E
authors.initials: E
authors.lastname: Nitzsche
authors.forename: U
authors.initials: U
authors.lastname: Oser
authors.forename: T
authors.initials: T
authors.lastname: Abdollahnia
authors.forename: M
authors.initials: M
authors.lastname: Nageleisen
authors.forename: M
authors.initials: M
authors.lastname: Zehender
authors.forename: H
authors.initials: H
authors.lastname: Just
authors.forename: U
authors.initials: U
authors.lastname: Solzbach
mesh_terms: D000368:Aged; D015901:Angiography, Digital Subtraction / Q000379:methods*; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography / Q000379:methods*; D003326:Coronary Circulation; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000628:therapy*; D003331:Coronary Vessels; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011856:Radiographic Image Enhancement / Q000379:methods; D012680:Sensitivity and Specificity