Indian childhood-like cirrhosis in three Saudi Arabian siblings.
Three Saudi siblings, two girls and one boy, presented at the ages of 7, 6 and 2.5 years, respectively, and were diagnosed as having features of Indian childhood cirrhosis (ICC). The two girls presented at a late stage of the disease and the boy was diagnosed during routine examination of the family. The initial presenting complaint was abdominal distention and pruritus. All three had a rapid and fatal course. There was no evidence of increased copper ingestion by the families, supporting the suggestion of a hereditary metabolic role in the aetiology of ICC. As far as we are aware, this is the first report of ICC in Saudi Arabian children.
Abiodun
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Department of Child Health, Asir Central Hospital, Abha, Kingdom of Saudi Arabia. yeleabi@gto.net.om
Albarki
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Dewan
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Annobil
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D002648:Child; D002675:Child, Preschool; D003241:Consanguinity; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications / Q000235:genetics*; D008297:Male; D009679:Nuclear Family; D011537:Pruritus / Q000209:etiology; D012529:Saudi Arabia