Periurethral vaginal adenocarcinoma of the intestinal type: report of two cases and review of the literature.
BACKGROUND
Vaginal adenocarcinomas in the absence of diethylstilbestrol (DES) exposure are rare neoplasms. Only a few cases with enteric type histology have been reported. Also rare are urethral adenocarcinomas in women.


METHODS
Two cases of vaginal adenocarcinoma of the intestinal type in the absence of DES exposure are presented. Both cases arose in the periurethral area, raising the issue of urethral as well as vaginal origin.


CONCLUSIONS
The possible histogenesis of these neoplasms is considered.
Heller
D S
DS
Department of Pathology and Laboratory Medicine, University of Medicine and Dentistry of New Jersey, Newark New Jersey, 07103, USA. hellerds@umdnj.edu
Merrell
M
M
Sama
J
J
Anderson
J
J
Cracchiolo
B
B
D000230:Adenocarcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D014523:Urethral Neoplasms / Q000473:pathology*; D014625:Vaginal Neoplasms / Q000473:pathology*