title: Critical aortic stenosis in the neonate. Clinical assessment and surgical outcome in 18 patients.
abstract: OBJECTIVE
  To assess neonates with aortic stenosis with early decompensation operated upon. (LCO) (CHF).
  
  
  METHODS
  A and retrospective study analyzing 6 neonates with LCO, group I (GI), and 12 neonates with CHF, group II (GII). Clinical radiographic, electrocardiographic and echocardiographic findings also provided comparative bases for the study, as did surgical and evolutional findings.
  
  
  RESULTS
  The mean ages at hospitalization and surgery (p = 0.0031) were 14.3 and 14.8 days in GI and 35.4 and 42.8 days in GII, respectively. Cardiac murmurs were more intense in GII (p = 0.0220). The aortic ring was smaller in GI (8.0 +/- 2.5mm) as compared to GII (11.4 +/ 1.4mm) (p = 0.2882). Ventricular function was reduced to 18 +/- 5.5% and 33.3 +/- 7.6% in GI and GII, respectively (p = 0.0162). Aortic atresia, however, was present only in 2 neonates in GI. Five of 6 patients in GI died but all patients in GII survived (p=0.0007). In the latter group, 84.6% of the patients were in functional class I (FC-I) in the long-term follow-up, with moderate residual lesions in 6 neonates, discrete residual lesions in 4, and reoperation in 2.
  
  
  CONCLUSIONS
  Aortic stenosis is a severe anomaly of the neonate, whose immediate evolution depends on the pre-operative anatomic and functional findings, and the late evolution essentially depends on the anatomic features of the valve.
authors.forename: E
authors.initials: E
authors.lastname: Atik
authors.forename: M
authors.initials: M
authors.lastname: Barbero-Marcial
authors.forename: E R
authors.initials: ER
authors.lastname: Iwahashi
authors.forename: J Y
authors.initials: JY
authors.lastname: Afiune
authors.forename: M
authors.initials: M
authors.lastname: Ebaid
mesh_terms: D001024:Aortic Valve Stenosis / Q000151:congenital / Q000503:physiopathology* / Q000601:surgery; D002303:Cardiac Output, Low / Q000503:physiopathology; D005260:Female; D006333:Heart Failure / Q000503:physiopathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D016896:Treatment Outcome