title: [Effect of amizon on structural modifications of liver nuclear chromatin from rats, intoxicated with tetrachloromethane].
abstract: The actions of the amizon on the antioxidant activity and free radicaloformation level in the nuclear chromatin fractions of rat liver methan tetrachlorid intoxication was studied using the Fe(+2)-induction biochemiluminescence and microcalorimetry methods. The amizon genomoprotective effect on the chromatin transcriptionally active fraction was shown.
authors.affiliation: Institute of Pharmacology and Toxicology, Academy of Medical Sciences of Ukraine, Kyiv.
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Hubskiyĭ
authors.forename: A H
authors.initials: AH
authors.lastname: Horiushko
authors.forename: I Ie
authors.initials: IIe
authors.lastname: Vistunova
authors.forename: O M
authors.initials: OM
authors.lastname: Marchenko
authors.forename: T M
authors.initials: TM
authors.lastname: Kurapova
authors.forename: V P
authors.initials: VP
authors.lastname: Danylenko
authors.forename: L H
authors.initials: LH
authors.lastname: Sachenko
mesh_terms: D000818:Animals; D002151:Calorimetry; D002252:Carbon Tetrachloride Poisoning / Q000473:pathology; D002467:Cell Nucleus / Q000187:drug effects / Q000378:metabolism; D056486:Chemical and Drug Induced Liver Injury / Q000473:pathology*; D002843:Chromatin / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D008163:Luminescent Measurements; D008297:Male; D011487:Protein Conformation; D011725:Pyridines / Q000494:pharmacology*; D011726:Pyridinium Compounds; D051381:Rats; D017208:Rats, Wistar; D014158:Transcription, Genetic
chemical_list: D002843:Chromatin; D011725:Pyridines; D011726:Pyridinium Compounds; C410106:enisamium