Promiscuous Watson-Crick cross-pairing within the family of pentopyranosyl (4'-->2') oligonucleotides.
[formula: see text] The D-beta-ribo, D-beta-xylo, L-alpha-lyxo, and L-alpha-arabino members of the pentopyranosyl (4'-->2') oligonucleotide family show efficient intersystem cross-pairing among each other. This family of configurationally isomeric and conformationally well-defined pairing systems offers an opportunity to study structural factors that determine cross-communication between informational oligonucleotide systems of different backbone structure.
Jungmann
O
O
Skaggs Institute for Chemical Biology, Scripps Research Institute, La Jolla, California 92037, USA.
Wippo
H
H
Stanek
M
M
Huynh
H K
HK
Krishnamurthy
R
R
Eschenmoser
A
A
D020029:Base Pairing; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000737:chemistry*
D009841:Oligonucleotides