[Acute myocardial damage from a pheochromocytoma].
Cardiac involvement in pheochromocytoma is rare but may be associated with serious clinical deterioration. A 70-year-old woman arrived at our Emergency Department because of chest discomfort, blood pressure lability, mild dyspnea and electrocardiographic signs suggesting an acute myocardial infarction. However two-dimensional echocardiogram did not show any segmental wall motion abnormalities but diffuse and severe left ventricular hypokinesia. The patient was treated with ACE-inhibitors and diuretics and did not receive thrombolytics or beta blocking agents. Creatine kinase-MB and troponin I were normal. Electrocardiogram and echocardiogram completely returned to normal within 1 week and a coronary angiography demonstrated normal coronary arteries. An increase in the catecholamine concentration in a 24-hour urinary sample suggested a pheochromocytoma that was confirmed by abdominal computerized tomography. During surgery, marked hypertension developed treated with sodium nitroprusside and labetalol, and after removal of the tumor severe hypotension required infusion of norepinephrine for several days.
Casazza
F
F
Divisione di Cardiologia, Azienda Ospedaliera San Carlo Borromeo, Milano. fcasazza@tin.it
Capozi
A
A
Conconi
B
B
Schiaffino
E
E
D000208:Acute Disease; D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D000311:Adrenal Glands / Q000473:pathology; D000315:Adrenalectomy; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis / Q000209:etiology*; D010673:Pheochromocytoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D013614:Tachycardia, Paroxysmal / Q000175:diagnosis / Q000209:etiology; D013617:Tachycardia, Supraventricular / Q000175:diagnosis / Q000209:etiology