title: Hepatitis A in day care centre.
abstract: A focal outbreak of hepatitis was detected in a day-care centre for children centrally located in Pune. The source of infection was suspected to be an 11-year-old child who probably got the infection from his school. Seven out of 15 children from day-care centre developed clinical hepatitis. Two cases of secondary infection were identified among the family contacts of infected children. Sera from all the nine sick children were positive for anti-hepatitis A virus-IgM antibodies. A stool sample from a case of secondary infection showed presence of HAV-RNA by RT-nested PCR. These findings proved that the outbreak was caused by hepatitis A virus.
authors.affiliation: National Institute of Virology, Pune.
authors.forename: S D
authors.initials: SD
authors.lastname: Chitambar
authors.forename: M S
authors.initials: MS
authors.lastname: Chadha
authors.forename: L R
authors.initials: LR
authors.lastname: Yeolekar
authors.forename: V A
authors.initials: VA
authors.lastname: Arankalle
mesh_terms: D000293:Adolescent; D002648:Child; D002656:Child Day Care Centers; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D006506:Hepatitis A / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D006801:Humans; D007194:India; D008297:Male