[Ultrastructure of nasal and paranasal mucosa in patients with chronic polypous rhinosinusitis].
Electron microscopic study of operative samples of nasal and paranasal mucosa from patients with chronic polypous rhinosinusitis has discovered changes in the mucosa typical for inflammation and ultrastructural changes. Epithelial layer underwent destruction. Adequate function of the remaining ciliary cells is doubtful even in minimal changes of their ciliary apparatus. The absence of the specialized contacts between the epithelyocytes indicates dysfunction of the selective ionic permeability. There was overgrowth of the reticular fibers of the basal membrane. Plasma cells exhibited marked dilation of the cysterns of the rough endoplasmic reticulum probably because of active accumulation of immunoglobulins or their precursors.
Zakharova
G P
GP
Il'inskaia
E V
EV
D002908:Chronic Disease; D006801:Humans; D009297:Nasal Mucosa / Q000648:ultrastructure*; D010256:Paranasal Sinuses / Q000648:ultrastructure*; D012220:Rhinitis / Q000175:diagnosis*; D012852:Sinusitis / Q000175:diagnosis*