Sequence analysis of the hemagglutinin gene of measles virus isolates in Denmark 1997-1998: no evidence of persistent circulation of measles virus in Denmark.
The hemagglutinin-coding region of 17 virus samples from 12 measles cases in Denmark during 1997-1998 was analysed by partial nucleotide sequencing. The cases appeared as three sporadic cases and two epidemics, both with a limited time course and geographical distribution. The measles strains identified from the three sporadic cases and two epidemics could be allocated to five different previously well-defined sequence groups consistent with the assumption that cases of measles in Denmark are due to repeated introduction from abroad rather than persistent circulation of strains in the population.
Dahl
L
L
Department of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark.
Christensen
L S
LS
Schöeller
S
S
Westh
H
H
Plesner
A M
AM
D000914:Antibodies, Viral / Q000097:blood; D003718:Denmark / Q000453:epidemiology; D006389:Hemagglutinins, Viral / Q000235:genetics*; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D015994:Incidence; D008457:Measles / Q000453:epidemiology / Q000635:transmission / Q000821:virology*; D008459:Measles virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D020133:Reverse Transcriptase Polymerase Chain Reaction
D000914:Antibodies, Viral; D006389:Hemagglutinins, Viral; D007075:Immunoglobulin M