title: A pseudolymphomatous skin reaction secondary to flucloxacillin.
abstract: We report the first case of a pseudolymphomatous skin reaction precipitated by flucloxacillin. Skin histology was suggestive of a cutaneous lymphoma, and DNA analysis by single stranded conformational polymorphism (SSCP) demonstrated T-cell receptor gamma gene monoclonality. Withdrawal of flucloxacillin led to immediate clinical improvement and gradual resolution of skin rash and lymph nodes.
authors.affiliation: Department of Microbiology, St Thomas' Hospital, London, UK.
authors.forename: M
authors.initials: M
authors.lastname: Melzer
authors.forename: F M
authors.initials: FM
authors.lastname: Keane
authors.forename: S J
authors.initials: SJ
authors.lastname: Eykyn
authors.forename: S M
authors.initials: SM
authors.lastname: Breathnach
mesh_terms: D000368:Aged; D005436:Floxacillin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010406:Penicillins / Q000009:adverse effects*; D019310:Pseudolymphoma / Q000139:chemically induced*; D012871:Skin Diseases / Q000139:chemically induced*
chemical_list: D010406:Penicillins; D005436:Floxacillin