[Membrane mechanisms of regulating Ca ion concentration in smooth muscle cells. II. System of passive Ca2+ transport in smooth muscles].
The aim of this review is to summarize some current aspects on the membrane mechanisms of energy-independent Ca2+ transport in the smooth muscles. The emphasis is placed on the characteristics of voltage-gated and receptor-operated calcium channels of plasma membrane and two major Ca2+ release channels of sarco(endo)plasmic reticulum: one is activated by IP3 and sensitive to heparin and the other by Ca2+ and sensitive to ryanodine. A brief discussion of the electro- and pharmacomechanical coupling mechanisms in the smooth muscle is given.
Babich
L H
LH
O.V. Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv.
D002118:Calcium / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000378:metabolism; D006706:Homeostasis; D017136:Ion Transport; D008931:Mitochondria, Muscle / Q000378:metabolism; D009130:Muscle, Smooth / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure
D002118:Calcium