title: Sequence analysis of the Rhop-3 gene of Plasmodium yoelii.
abstract: The 110 kDa/Rhop-3 rhoptry protein of Plasmodium falciparum is non-covalently associated with two other proteins, the 140 kDa Rhop-1 and the 130 kDa Rhop-2. cDNAs encoding Rhop-3 from Plasmodium yoelii were isolated using rhoptry-specific antisera from Plasmodium falciparum, P. yoelii, and Plasmodium chabaudi. The cDNAs encoded peptides with partial homology to the C-terminal region (residues 541-861) of P. falciparum Rhop-3. Core regions of homology to the P. falciparum gene will be useful in determining the biological role of Rhop-3 and its potential as a vaccine candidate for malaria.
authors.affiliation: Cleveland State University, Department of Biological, Geological and Environmental Sciences, Ohio 44115, USA.
authors.forename: R N
authors.initials: RN
authors.lastname: Anthony
authors.forename: J
authors.initials: J
authors.lastname: Yang
authors.forename: J A
authors.initials: JA
authors.lastname: Krall
authors.forename: T Y
authors.initials: TY
authors.lastname: Sam-Yellowe
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D015723:Gene Library; D017125:Genes, Protozoan; D008969:Molecular Sequence Data; D010963:Plasmodium falciparum / Q000235:genetics; D010967:Plasmodium yoelii / Q000235:genetics*; D015800:Protozoan Proteins / Q000235:genetics*; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity
chemical_list: D015800:Protozoan Proteins; C065352:rhoptry associated protein, Plasmodium