title: Promiscuous Watson-Crick cross-pairing within the family of pentopyranosyl (4'-->2') oligonucleotides.
abstract: [formula: see text] The D-beta-ribo, D-beta-xylo, L-alpha-lyxo, and L-alpha-arabino members of the pentopyranosyl (4'-->2') oligonucleotide family show efficient intersystem cross-pairing among each other. This family of configurationally isomeric and conformationally well-defined pairing systems offers an opportunity to study structural factors that determine cross-communication between informational oligonucleotide systems of different backbone structure.
authors.affiliation: Skaggs Institute for Chemical Biology, Scripps Research Institute, La Jolla, California 92037, USA.
authors.forename: O
authors.initials: O
authors.lastname: Jungmann
authors.forename: H
authors.initials: H
authors.lastname: Wippo
authors.forename: M
authors.initials: M
authors.lastname: Stanek
authors.forename: H K
authors.initials: HK
authors.lastname: Huynh
authors.forename: R
authors.initials: R
authors.lastname: Krishnamurthy
authors.forename: A
authors.initials: A
authors.lastname: Eschenmoser
mesh_terms: D020029:Base Pairing; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000737:chemistry*
chemical_list: D009841:Oligonucleotides