title: Transition metal complexes in organic synthesis, part 59.(1) First enantioselective total synthesis of lavanduquinocin, a potent neuronal cell protecting substance from streptomyces viridochromogenes.
abstract: Using (R)-propene oxide as a chiral building block a convergent enantioselective synthesis of the potent neuronal cell protecting alkaloid lavanduquinocin has been accomplished by the iron-mediated one-pot construction of the carbazole framework.
authors.affiliation: Institut fur Organische Chemie, Universitat Karlsruhe, Karlsruhe, Germany. knoe@ochhades.chemie.uni-karlsruhe.de
authors.forename: H J
authors.initials: HJ
authors.lastname: Knolker
authors.forename: E
authors.initials: E
authors.lastname: Baum
authors.forename: K R
authors.initials: KR
authors.lastname: Reddy
mesh_terms: D000818:Animals; D002227:Carbazoles / Q000138:chemical synthesis*; D018360:Crystallography, X-Ray; D008670:Metals / Q000737:chemistry; D008956:Models, Chemical; D008958:Models, Molecular; D009474:Neurons / Q000378:metabolism*; D018696:Neuroprotective Agents / Q000138:chemical synthesis; D013237:Stereoisomerism; D013302:Streptomyces / Q000378:metabolism*
chemical_list: D002227:Carbazoles; D008670:Metals; D018696:Neuroprotective Agents; C095334:lavanduquinocin