Multiple site silicon-based probes for chronic recordings in freely moving rats: implantation, recording and histological verification.
This paper describes the procedure of assembling a miniature microdrive and silicon probe system for surgical implantation into the adult rat brain. Successful recordings of single and multiunit activity with parallel depth profiles of spontaneous and evoked field potentials are shown. The procedure for histological verification of the position of the silicon probe is described.
Bragin
A
A
Department of Neurology, UCLA School of Medicine, 2147 RNRC, 710 Westwood Plaza, Los Angeles, CA 90095-1769, USA. abragin@ucla.edu
Hetke
J
J
Wilson
C L
CL
Anderson
D J
DJ
Engel
J
J
Buzsáki
G
G
D000367:Age Factors; D000818:Animals; D001921:Brain / Q000502:physiology*; D004567:Electrodes, Implanted; D004594:Electrophysiology / Q000295:instrumentation* / Q000379:methods*; D005071:Evoked Potentials / Q000502:physiology; D008124:Locomotion / Q000502:physiology*; D051381:Rats; D012825:Silicon
D012825:Silicon