title: Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1.
authors.affiliation: Georgetown University School of Medicine, Department of Biochemistry and Molecular Biology, 3900 Reservoir Rd, NW, Washington, DC 20007, USA. smulson@bc.georgetown.edu
authors.forename: M E
authors.initials: ME
authors.lastname: Smulson
authors.forename: C M
authors.initials: CM
authors.lastname: Simbulan-Rosenthal
authors.forename: A H
authors.initials: AH
authors.lastname: Boulares
authors.forename: A
authors.initials: A
authors.lastname: Yakovlev
authors.forename: B
authors.initials: B
authors.lastname: Stoica
authors.forename: S
authors.initials: S
authors.lastname: Iyer
authors.forename: R
authors.initials: R
authors.lastname: Luo
authors.forename: B
authors.initials: B
authors.lastname: Haddad
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Wang
authors.forename: T
authors.initials: T
authors.lastname: Pang
authors.forename: M
authors.initials: M
authors.lastname: Jung
authors.forename: A
authors.initials: A
authors.lastname: Dritschilo
authors.forename: D S
authors.initials: DS
authors.lastname: Rosenthal
mesh_terms: D016475:3T3 Cells; D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D004260:DNA Repair / Q000502:physiology*; D004268:DNA-Binding Proteins; D050684:E2F Transcription Factors; D050687:E2F1 Transcription Factor; D006801:Humans; D019169:Jurkat Cells; D051379:Mice; D011064:Poly Adenosine Diphosphate Ribose / Q000502:physiology*; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism*; D056465:Retinoblastoma-Binding Protein 1; D050680:Transcription Factor DP1; D014157:Transcription Factors / Q000502:physiology*; D016159:Tumor Suppressor Protein p53 / Q000502:physiology*
chemical_list: C533431:Arid4a protein, mouse; D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; D050684:E2F Transcription Factors; D050687:E2F1 Transcription Factor; C493753:E2F1 protein, human; C493754:E2f1 protein, mouse; D056465:Retinoblastoma-Binding Protein 1; D050680:Transcription Factor DP1; D014157:Transcription Factors; D016159:Tumor Suppressor Protein p53; D011064:Poly Adenosine Diphosphate Ribose; D011065:Poly(ADP-ribose) Polymerases