title: SOX8 expression during chick embryogenesis.
abstract: We have isolated the SOX8 gene from the chicken embryo. This gene shows a high degree of sequence homology to SOX9 and SOX10. Detailed analysis of SOX8 expression by whole-mount in situ shows a dynamic and restricted expression pattern during chick development. SOX8 is expressed in the somitic derivative, the dermomyotome, the developing heart, pancreas, enteric neurone system, limb and the neural tube. This is the first detailed expression analysis of SOX8 in any species
authors.affiliation: Department of Pediatrics, Centre for Hormone Research, University of Melbourne, Royal Children's Hospital, Australia.
authors.forename: K M
authors.initials: KM
authors.lastname: Bell
authors.forename: P S
authors.initials: PS
authors.lastname: Western
authors.forename: A H
authors.initials: AH
authors.lastname: Sinclair
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002642:Chick Embryo; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000378:metabolism; D005121:Extremities / Q000196:embryology; D018507:Gene Expression Regulation, Developmental; D008969:Molecular Sequence Data; D018482:Muscle, Skeletal / Q000196:embryology; D010179:Pancreas / Q000196:embryology; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism
chemical_list: D004268:DNA-Binding Proteins; D014157:Transcription Factors