title: Management of testicular seminoma. Our experience.
abstract: BACKGROUND
  The authors report their experience in the management of seminomas.
  
  
  METHODS
  They examine 12 cases of seminoma among a series of 19 patients with testicular germ cell tumours observed at the Second Surgical Department of the Second University of Naples.
  
  
  RESULTS
  Their results showed a better prognosis for patients in early stage of the disease who underwent surgery and adjuvant prophylactic radiotherapy; good survival rates for patients in advanced stages of the disease were achieved by the combined use of surgery, adjuvant radiotherapy and chemotherapy.
  
  
  CONCLUSIONS
  The authors discuss risk factors, clinical and diagnostic features of seminomas, relating their prognosis with the combined use of both surgery and adjuvant therapies. They consider total orchiectomy, followed by prophylactic radiotherapy, the treatment of choice, especially in stages IA and IIA. They don't perform the routine retroperitoneal lymphadenectomy, differently from American authors, who always achieve it to stage the disease.
  
  
  CONCLUSIONS
  The authors stress the improvement in the prognosis of seminoma, which has actually reached the 98% of five-year survival rate, for stages I and II.
authors.affiliation: Istituto di Patologia Speciale, Chirurgica e Propedeutica Clinica, II Università degli Studi di Napoli.
authors.forename: P
authors.initials: P
authors.lastname: Sperlongano
authors.forename: D
authors.initials: D
authors.lastname: Pisaniello
authors.forename: U
authors.initials: U
authors.lastname: Di Mauro
authors.forename: D
authors.initials: D
authors.lastname: Pone
authors.forename: E
authors.initials: E
authors.lastname: Casoli
mesh_terms: D000293:Adolescent; D000328:Adult; D017024:Chemotherapy, Adjuvant; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D009367:Neoplasm Staging; D009919:Orchiectomy; D011182:Postoperative Care; D011300:Preoperative Care; D018714:Radiotherapy, Adjuvant; D012307:Risk Factors; D018239:Seminoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*