The supply of blood products in 10 different systems or countries.
Countries vary greatly in their ability to produce their own blood products including albumin and IVIgG. Part of this variability depends on the supply of plasma within the country. As has been seen most recently in the UK, the quality of the plasma and its acceptability for plasma fractionation must also be considered. Therefore concerns regarding the quality of the plasma have been added to those regarding the quantity.Only a few countries are nationally self sufficient in plasma. This has a marked effect on blood product availability and therefore the ability to treat patients. Unlike most pharmaceuticals, the plasma fractionation industry must rely, for its raw products, on plasma obtained from blood donors. As such this puts it in a potentially compromised situation since neither the supply nor the quality of the raw material can be assured and both of those will vary with time. This paper reviews the processes through which blood products are made available in 10 different systems including: Canada, England, France, Italy, Norway Scotland, Sweden, Switzerland, South Africa and USA. A series of specific questions were posed and the responses received from the various coauthors and other respondents provide comparative data on blood product availability in different areas of the world.
Rock
G
G
Ottawa Hospital and University of Ottawa, c/o Suite 101, 270 Sandridge Road, K1L 5A2, Ottawa, Ont., Canada. cag@magi.com
Akerblom
O
O
Berséus
O
O
Herve
P
P
Jacobs
P
P
Kelly
T
T
MacPherson
J
J
Nydegger
U
U
Segatchian
G
G
Urbaniak
S
S
Valbonesi
M
M
D001771:Blood Banks / Q000191:economics / Q000458:organization & administration; D001803:Blood Transfusion / Q000191:economics; D002170:Canada; D003365:Costs and Cost Analysis; D003625:Data Collection; D004739:England; D005602:France; D006801:Humans; D007558:Italy; D009313:National Health Programs / Q000191:economics / Q000458:organization & administration; D009664:Norway; D012606:Scotland; D013019:South Africa; D013548:Sweden; D013557:Switzerland; D014481:United States