title: Three-dimensional numerical simulations of flow through a stenosed coronary bypass.
abstract: This work analyzes the flow patterns at the anastomosis of a stenosed coronary bypass. Three-dimensional numerical simulations are performed using a finite elements method. We consider a geometrical model of the host coronary artery with and without a 75% severity stenosis for three different locations from the anastomosis. The flow features - velocity profiles, secondary motions and wall shear stresses - are compared for different configurations of the flow rate and of the distance of the anastomosis from the site of occlusion (called distance of grafting). The combination of the junction flow effects - counter rotating vortices - with the stenosis effects - confined jet flow - is particularly important when the distance of grafting is short. Given that the residual flow issued from the pathologic stenosis being non-negligible after two weeks grafting, models without stenosis cannot predict the evolution of the wall shear stress in the vicinity of the anastomosis.
authors.affiliation: IRPHE UMR n degrees 6594/ESM2, Laboratoire de Biomécanique Cardiovasculaire, Technopôle de Château Gombert, Marseille Cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Bertolotti
authors.forename: V
authors.initials: V
authors.lastname: Deplano
mesh_terms: D001158:Arteries / Q000502:physiology; D001783:Blood Flow Velocity; D003198:Computer Simulation; D003251:Constriction, Pathologic / Q000503:physiopathology; D001026:Coronary Artery Bypass; D017276:Friction; D006439:Hemodynamics; D006801:Humans; D008955:Models, Cardiovascular; D019737:Transplants