title: Immunocontrol in dogs.
abstract: Population control in dogs and cats is an important goal for many groups. Control measures over the years has included surgery, hormonal therapy and more recently immunological control. The current presentation discusses dog population control with an emphasis on immunologic control. Specifically, vaccination with purified zona pellucida (ZP) glycoproteins leads initially to immunocontraception and then to the profound and irreversible changes of immunosterilization. The preliminary studies are extremely encouraging on developing a vaccine for lasting canine population control.
authors.affiliation: Department of Large Animal Medicine and Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens 30602-7385, USA. rfh@calc.vet.uga.edu
authors.forename: R A
authors.initials: RA
authors.lastname: Fayrer-Hosken
authors.forename: H D
authors.initials: HD
authors.lastname: Dookwah
authors.forename: C I
authors.initials: CI
authors.lastname: Brandon
mesh_terms: D000818:Animals; D004285:Dogs / Q000276:immunology*; D004527:Egg Proteins / Q000276:immunology; D008562:Membrane Glycoproteins / Q000276:immunology; D011155:Population Control / Q000379:methods; D011956:Receptors, Cell Surface; D013245:Sterilization, Reproductive / Q000379:methods / Q000662:veterinary*; D014611:Vaccination / Q000662:veterinary; D000072216:Zona Pellucida Glycoproteins
chemical_list: D004527:Egg Proteins; D008562:Membrane Glycoproteins; D011956:Receptors, Cell Surface; D000072216:Zona Pellucida Glycoproteins