Fine needle aspiration cytology of well-differentiated liposarcoma. A report of two cases.
BACKGROUND
Well-differentiated liposarcoma is difficult to diagnose on fine needle aspiration cytology (FNAC) smears and may create considerable diagnostic problems.


METHODS
Males aged 60 and 45 years presented with a swelling in the groin and retroperitoneal region, respectively. FNAC showed large cells with multilobulated nuclei and mature-looking fat tissue. A soft tissue tumor with bizarre cells was diagnosed cytologically in case 1 and liposarcoma in case 2. Histologically, both cases were diagnosed as well-differentiated sclerosing liposarcoma.


CONCLUSIONS
The cytologic diagnosis of well-differentiated liposarcoma should be done with caution, and the sites should be taken into consideration. Deep-seated tumors with large, bizarre, giant cells should have wide excision as they recur more frequently.
Dey
P
P
Department of Cytology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. pranab@ch1.dot.net.n
D000008:Abdominal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D001707:Biopsy, Needle; D003581:Cytodiagnosis; D006119:Groin / Q000473:pathology; D006801:Humans; D008080:Liposarcoma / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D012187:Retroperitoneal Space / Q000473:pathology; D012598:Sclerosis / Q000473:pathology