title: The scientific origin of life. Considerations on the evolution of information, leading to an alternative proposal for explaining the origin of the cell, a semantically closed system.
abstract: We hypothesize that the origin of life, that is, the origin of the first cell, cannot be explained by natural selection among self-replicating molecules, as is done by the RNA-world hypothesis. To circumvent the chicken and egg problem associated with semantic closure of the cell--no replication of information molecules (nucleotide strands) without functional enzymes, no functional enzymes without encoding in information molecules--a prebiotic evolutionary process is proposed that, from the informational point of view, must somehow have resembled the current scientific process. The cell was the outcome of interactions of a complex premetabolic community, with information molecules that were devoid of self-replicative properties. In a comparable manner, scientific progress is possible, essentially because of interaction between a complex cultural society and permanent information carriers like printed matter. This may eventually lead to self-replicating technology in which semantic closure occurs anew. Explaining the origin of life as a scientific process might provide a unifying theory for the evolution of information, wherebye at two moments symbolization/encoding of interactions into permanent information occurred: at one moment that of chemical interaction and at another moment that of animal behavior interaction. In one event this encoding led to autonomously duplicating chemistry (the cell), an event that possibly may be one of the outcomes of current scientific progress.
authors.affiliation: Department of Clinical Chemistry, Microbiology & Immunology, University Hospital, Gent, Belgium. Mario.Vaneechoutte@rug.ac.be
authors.forename: M
authors.initials: M
authors.lastname: Vaneechoutte
mesh_terms: D000069497:Origin of Life; D012313:RNA / Q000235:genetics; D012586:Science / Q000379:methods; D012660:Semantics
chemical_list: D012313:RNA