X-linked non-specific mental retardation.
Non-specific mental retardation is a very common and genetically heterogeneous disorder but, to date, only six genes related to this condition have been identified. Five of these six have been found in the past two years, through positional-cloning efforts of mapped X-linked families. The characteristics of the newly identified genes are providing insights into the molecular mechanisms of mental impairment and the development of cognitive functions.
Toniolo
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Institute of Genetics, Biochemistry and Evolution, Consiglio Nazionale delle Recherche, 27100 Pavia, Italy. toniolo@igbe.pv.cnr.it
D'Adamo
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P
D002874:Chromosome Mapping; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D014960:X Chromosome