What determines the rate of sequence evolution?
High rates of amino-acid sequence evolution have sometimes been considered to be diagnostic for genes undergoing adaptive change. However, two recent studies have shown that rapid evolution of amino-acid sequence can also be congruent with neutrality.
Brookfield
J F
JF
Institute of Genetics, University of Nottingham, Queens Medical Centre, Nottingham, NG7 2UH, UK. John.Brookfield@nottingham.ac.uk
D000222:Adaptation, Physiological / Q000235:genetics; D000595:Amino Acid Sequence; D000818:Animals; D005075:Biological Evolution; D004331:Drosophila melanogaster / Q000235:genetics; D019143:Evolution, Molecular; D008954:Models, Biological; D013995:Time