[The biomedical aspects of nitric oxide cycles and of the superoxide anion radical].
The paper presents a concept of the cycles of nitric oxide and superoxide radical anion and discusses the biomedical aspects of these cycles. The developed concepts and their related ideas suggest that the mechanism of the cycle(s) shows the naturally latent regularity and assigns a meaning to orderliness in the system of free radical compounds. By their chemical nature, the latter are well-known to tend to behave aggressively and commonly unpredictably, which frequently causes abnormalities of various genesis. In the author's opinion, the mechanism of antiradical protection of cells and the body as a whole is built into the very cyclic arrangement of metabolic processes which are attended by the formation of free radicals. Failure of this cyclic mechanism may be a cause of many diseases.
Reutov
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D000818:Animals; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D009569:Nitric Oxide / Q000096:biosynthesis / Q000502:physiology*; D019001:Nitric Oxide Synthase / Q000378:metabolism; D009572:Nitrite Reductases / Q000378:metabolism; D010101:Oxygen Consumption / Q000502:physiology; D010507:Periodicity; D013481:Superoxides / Q000378:metabolism*
D005609:Free Radicals; D013481:Superoxides; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D009572:Nitrite Reductases