title: Solid-phase oligosaccharide synthesis: preparation of complex structures using a novel linker and different glycosylating agents.
abstract: [formula: see text] A beta-(1-->4)-linked trisaccharide was prepared in 53% yield on a polymer support using glycosyl phosphates and released by cross-metathesis of a novel linker to reveal the anomeric n-pentenyl glycoside. Heptasaccharide 33 was prepared in 9% yield in 14 steps.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139, USA.
authors.forename: R B
authors.initials: RB
authors.lastname: Andrade
authors.forename: O J
authors.initials: OJ
authors.lastname: Plante
authors.forename: L G
authors.initials: LG
authors.lastname: Melean
authors.forename: P H
authors.initials: PH
authors.lastname: Seeberger
mesh_terms: D002240:Carbohydrate Sequence; D006031:Glycosylation; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000138:chemical synthesis*
chemical_list: D009844:Oligosaccharides