title: Living liver donor surgery: report of initial anesthesia experience.
abstract: The charts and anesthetic records of 12 patients who donated the left lateral segment of their liver to a related infant or child to treat liver failure were retrospectively reviewed. Blood loss, need for transfusion, fluids administered, surgical length, and perioperative complications were investigated. The records also were examined to determine the hemodynamic stability of patients undergoing donor hepatectomy to assess their need for invasive monitoring. There were no episodes of hypotension or hemodynamic instability. The average operating time was 9.6 +/- 1.1 hours. The blood loss was 562 +/- 244 mL (range 300 to 1100 mL). Four patients received their own cell saver blood (200 mL, 220 mL, 300 mL, 475 mL), and one patient received 1 U (350 mL) of predonated autologous blood. The average hemoglobin decreased significantly (p = 0.001) from a preoperative value of 14.1 +/- 1.2 to 12.3 +/- 1.8 g/dL in the recovery room. All patients were extubated in the operating room or recovery room. Patients were discharged home in 6.9 +/- 1.3 days (range 5 to 9 days). Living-related liver resection can be performed with noninvasive monitoring and without the need for heterologous blood products.
authors.affiliation: Department of Anesthesiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA. beebe001@tc.umn.edu
authors.forename: D S
authors.initials: DS
authors.lastname: Beebe
authors.forename: R
authors.initials: R
authors.lastname: Carr
authors.forename: V
authors.initials: V
authors.lastname: Komanduri
authors.forename: A
authors.initials: A
authors.lastname: Humar
authors.forename: R
authors.initials: R
authors.lastname: Gruessner
authors.forename: K G
authors.initials: KG
authors.lastname: Belani
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D016063:Blood Loss, Surgical; D001803:Blood Transfusion; D001804:Blood Transfusion, Autologous; D002648:Child; D002675:Child, Preschool; D005260:Female; D005440:Fluid Therapy; D006439:Hemodynamics; D006454:Hemoglobins / Q000032:analysis; D006498:Hepatectomy / Q000009:adverse effects / Q000379:methods; D006801:Humans; D007022:Hypotension / Q000517:prevention & control; D007223:Infant; D007431:Intraoperative Complications; D007442:Intubation, Intratracheal; D007902:Length of Stay; D017093:Liver Failure / Q000601:surgery; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D006454:Hemoglobins