Fructo-oligosaccharide supplementation: effects on metabolic, endocrine and hematological traits in veal calves.
Fructo-oligosaccharides (FOS) are soluble fibres which exert various effects in the gastrointestinal tract, and induce metabolic and endocrine changes. The effects are favourable in diabetes mellitus, and may be favourable in veal calves, which during late periods of fattening often develop hyperglycemia, glucosuria and insulin resistance, especially during high lactose intake. Based on this we have studied metabolic, endocrine and haematological traits in veal calves (Simmental x Red Holstein) fed FOS (10 g/day; group GrF) or no FOS (group GrC). Whole milk and milk replacer in both groups, on a kg body weight basis, were fed in identical amounts. Experiments, lasting for 3 weeks, started when calves were 10 weeks old and weighed 117 kg. During week 3 lactose was supplemented to enhance post-absorptive glucose loads. Feed intakes were similar in both groups, but weight gain tended to be higher in GrF than GrC. The post-prandial increase of glucose concentrations was significantly smaller, of lactate tended to be smaller, and growth hormone peak frequency tended to be lower, whereas maximal insulin concentrations reached post-prandially were significantly higher in GrF than GrC. Eosinophil granulocytes increased during FOS feeding. In conclusion, FOS had basically similar effects on metabolic and endocrine traits in veal calves as in animals and humans with diabetes mellitus, but changes were small, albeit more prominent after lactose loads.
Kaufhold
J
J
Division of Nutritional Pathology, University of Berne, Switzerland.
Hammon
H M
HM
Blum
J W
JW
D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D001798:Blood Proteins / Q000032:analysis; D001835:Body Weight; D002417:Cattle / Q000097:blood / Q000378:metabolism* / Q000502:physiology; D004043:Dietary Fiber / Q000378:metabolism*; D019587:Dietary Supplements; D004906:Erythrocyte Count / Q000662:veterinary; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005632:Fructose / Q000378:metabolism* / Q000502:physiology; D005934:Glucagon / Q000032:analysis; D006400:Hematocrit / Q000662:veterinary; D006454:Hemoglobins / Q000032:analysis; D007328:Insulin / Q000097:blood; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D019344:Lactic Acid / Q000097:blood; D007958:Leukocyte Count / Q000662:veterinary; D009844:Oligosaccharides / Q000378:metabolism*; D011897:Random Allocation; D012709:Serum Albumin / Q000032:analysis; D013974:Thyroxine / Q000097:blood; D014280:Triglycerides / Q000097:blood; D014284:Triiodothyronine / Q000097:blood; D014508:Urea / Q000097:blood
D001786:Blood Glucose; D001798:Blood Proteins; D004043:Dietary Fiber; D005230:Fatty Acids, Nonesterified; D006454:Hemoglobins; D007328:Insulin; D009844:Oligosaccharides; D012709:Serum Albumin; D014280:Triglycerides; D014284:Triiodothyronine; D005632:Fructose; D019344:Lactic Acid; D007334:Insulin-Like Growth Factor I; D014508:Urea; D005934:Glucagon; D013974:Thyroxine