Prevalence of solar damage and actinic keratosis in a Merseyside population.
This study examines the prevalence of sun-related damage to the skin in a caucasian population in north-west England. The importance of constitutional factors (complexion, skin type and age) as well as environmental and occupational exposures for the development of actinic keratosis (AK) and skin cancers was assessed in people over 40 years of age attending outpatient clinics (non-dermatology) at four centres in north-west England (Mersey region). Nine hundred and sixty-eight volunteers (531 men and 437 women) were recruited. The overall prevalence of AK was 15.4% in men and 5.9% in women. The prevalence was strongly related to age in both sexes, being 34.1% and 18.2%, respectively, in men and women aged 70 years and above, and was most strongly related to two objective signs of sun exposure, namely degree of solar elastosis and presence of solar lentigines. The prevalence of AK was higher in subjects with red hair and freckles, particularly women. There was no evidence of an increased prevalence of AK in relation to any occupation. There was a high prevalence of seborrhoeic keratosis and viral warts in both sexes, which was age-related in the case of seborrhoeic keratosis. Ten cases of basal cell carcinoma, eight cases of Bowen's disease and one case of malignant melanoma were identified. This study shows that the sun exposure received in 'normal' life in England is sufficient to cause potentially malignant skin damage in a significant proportion of the population.
Memon
A A
AA
Dermatology Unit, Department of Medicine, PO Box 169, University of Liverpool, Liverpool L69 3BX, U.K.
Tomenson
J A
JA
Bothwell
J
J
Friedmann
P S
PS
D000328:Adult; D017677:Age Distribution; D000368:Aged; D004739:England / Q000453:epidemiology; D005260:Female; D005838:Genotype; D006801:Humans; D007642:Keratosis / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology*; D009784:Occupational Diseases / Q000453:epidemiology; D010641:Phenotype; D011230:Precancerous Conditions / Q000453:epidemiology*; D015995:Prevalence; D017678:Sex Distribution; D012878:Skin Neoplasms / Q000453:epidemiology*; D013472:Sunlight / Q000009:adverse effects*