Effect of Bacillus thuringiensis toxins on the midgut of the nun moth Lymantria monacha.
Three steps of the proposed mode of action of Bacillus thuringiensis toxins have been studied in Lymantria monacha. We demonstrated that only the toxins that caused typical pathological changes in midgut epithelial cells and bound to the midgut brush border membrane were able to drastically reduce the midgut transepithelial voltage of the nun moth.
Rausell
C
C
Departamento de Genética, Universitat de València, Dr. Moliner 50, Burjassot, Valencia, 46100, Spain.
De Decker
N
N
García-Robles
I
I
Escriche
B
B
Van Kerkhove
E
E
Real
M D
MD
Martínez-Ramírez
A C
AC
D000818:Animals; D001413:Bacillus thuringiensis / Q000378:metabolism*; D001427:Bacterial Toxins / Q000494:pharmacology*; D007422:Intestines / Q000187:drug effects* / Q000473:pathology / Q000503:physiopathology; D009036:Moths / Q000187:drug effects* / Q000502:physiology
D001427:Bacterial Toxins