Characterization of the physicochemical properties of the micelles of platelet-activating factor (C18:0).
The purpose of this study was to clarify the physicochemical properties of the micelles of platelet-activating factor (PAF; C18:0). The critical micelle concentration (CMC) of PAF (C18:0) was determined (0.20 microM) using fluorescence techniques. The fluidity and the micropolarity of the PAF (C18:0) micelle were similar to those of the micelle of stearoyl lysophosphatidylcholine.
Asai
Y
Y
Formulation Research Laboratory, Kawashima, Eisai Company, Limited, Gifu, Japan.
Nomura
T
T
Murahashi
N
N
Iwamoto
K
K
D000817:Anilino Naphthalenesulfonates / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D008244:Lysophosphatidylcholines / Q000737:chemistry; D000432:Methanol / Q000737:chemistry; D008823:Micelles; D010078:Oxazines / Q000737:chemistry; D010972:Platelet Activating Factor / Q000737:chemistry*
D000817:Anilino Naphthalenesulfonates; D005456:Fluorescent Dyes; D008244:Lysophosphatidylcholines; D008823:Micelles; D010078:Oxazines; D010972:Platelet Activating Factor; C026564:stearoyl alpha-lysolecithin; C044808:nile red; D000432:Methanol