title: 5-Amino-dU: a nucleoside analogue in the central strand of DNA triplex for orientation selective binding of A/G/C/T in the third strand.
abstract: [formula: see text] 5-Amino-dU, a designed nucleoside analogue, when placed in the central strand of DNA triple helix, recognizes all four bases A, G, C, and T in the third strand, with a selectivity based on the orientation (parallel/antiparallel) of the third strand.
authors.affiliation: Division of Organic Synthesis, National Chemical Laboratory, Pune, India.
authors.forename: V S
authors.initials: VS
authors.lastname: Rana
authors.forename: K N
authors.initials: KN
authors.lastname: Ganesh
mesh_terms: D004247:DNA / Q000737:chemistry*; D004268:DNA-Binding Proteins / Q000737:chemistry; D003857:Deoxyuridine / Q000031:analogs & derivatives* / Q000737:chemistry; D006860:Hydrogen Bonding; D009690:Nucleic Acid Conformation; D013056:Spectrophotometry, Ultraviolet
chemical_list: D004268:DNA-Binding Proteins; C410463:5-amino-2'-deoxyuridine; D004247:DNA; D003857:Deoxyuridine