title: Beta-hydroxy beta-methylbutyrate (HMB) supplementation does not influence the urinary testosterone: epitestosterone ratio in healthy males.
abstract: Six healthy, recreationally active, males undertook two weeks supplementation with beta-Hydroxy beta-Methylbutyrate (HMB). Supplementation was in capsule form with 3 g consumed each day in three even doses of 1 g at main meals. Mid stream urine samples were collected prior to, as well as, after one and two weeks of supplementation and subsequently analysed for testosterone and epitestosterone. The testosterone: epitestosterone ratio was not affected by 2 weeks of HMB supplementation (mean +/- SD baseline 1.02 +/- 0.68; week one 0.98 +/- 0.61; week two 0.92 +/- 0.62). Our results support the claim that supplementation with HMB at the doses recommended will not influence the urinary testosterone: epitestosterone ratio and thus not breach doping policies of the International Olympic Committee for exogenous testosterone or precursor administration.
authors.affiliation: Department of Physiology and Applied Nutrition, Australian Institute of Sport, Canberra.
authors.forename: G J
authors.initials: GJ
authors.lastname: Slater
authors.forename: P A
authors.initials: PA
authors.lastname: Logan
authors.forename: T
authors.initials: T
authors.lastname: Boston
authors.forename: C J
authors.initials: CJ
authors.lastname: Gore
authors.forename: A
authors.initials: A
authors.lastname: Stenhouse
authors.forename: A G
authors.initials: AG
authors.lastname: Hahn
mesh_terms: D000328:Adult; D019587:Dietary Supplements; D004300:Doping in Sports; D004845:Epitestosterone / Q000652:urine*; D006801:Humans; D007390:International Agencies; D008297:Male; D013739:Testosterone / Q000652:urine*; D014631:Valerates / Q000008:administration & dosage*
chemical_list: D014631:Valerates; C004961:beta-hydroxyisovaleric acid; D013739:Testosterone; D004845:Epitestosterone