Total synthesis of (+/-)-isoschizogamine.
[formula: see text] Isoschizogamine has been prepared for the first time. The synthesis requires eight steps from a readily available ketone starting material and features an aminal-forming cyclization that is based on a proposed biosynthetic transformation.
Hubbs
J L
JL
Department of Chemistry, University of California, Berkeley 94720, USA.
Heathcock
C H
CH
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D026121:Indole Alkaloids; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry
D000470:Alkaloids; D026121:Indole Alkaloids; D007211:Indoles; C409122:isoschizogamine