title: Multiple origins of Tibetan Y chromosomes.
abstract: The genetic origin of Tibetans was investigated using Y chromosome markers. A total of three populations were studied, two from central Tibet speaking central Tibetan and one from Yunnan speaking Kham. Two dominant paternal lineages (>80%) were identified in all three populations with one possibly from central Asia (YAP+) and the other from east Asia (M122C). We conclude that Tibetan Y chromosomes may have been derived from two different gene pools, given the virtual absence of M122C in central Asia and YAP+ in east Asia, with drift an unlikely mechanism accounting for these observations.
authors.affiliation: Institute of Medical Biology, The Chinese Academy of Medical Sciences, Kunming, Yunnan, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Qian
authors.forename: B
authors.initials: B
authors.lastname: Qian
authors.forename: B
authors.initials: B
authors.lastname: Su
authors.forename: J
authors.initials: J
authors.lastname: Yu
authors.forename: Y
authors.initials: Y
authors.lastname: Ke
authors.forename: Z
authors.initials: Z
authors.lastname: Chu
authors.forename: L
authors.initials: L
authors.lastname: Shi
authors.forename: D
authors.initials: D
authors.lastname: Lu
authors.forename: J
authors.initials: J
authors.lastname: Chu
authors.forename: L
authors.initials: L
authors.lastname: Jin
mesh_terms: D020087:Alu Elements; D001209:Asia, Central; D044466:Asian People / Q000235:genetics*; D005075:Biological Evolution; D002681:China / Q000208:ethnology; D004641:Emigration and Immigration; D005220:Fathers; D005788:Gene Pool; D005819:Genetic Markers; D006239:Haplotypes; D006801:Humans; D018609:Tibet; D014998:Y Chromosome
chemical_list: D005819:Genetic Markers