Effect of Punica granatum Linn. (flowers) on blood glucose level in normal and alloxan-induced diabetic rats.
'Gulnar farsi', male abortive flowers of Punica granatum L., are used for the treatment of diabetes mellitus in Unani medicine. Oral administration of its aqueous-ethanolic (50%, v/v) extract led to significant blood glucose lowering effect in normal, glucose-fed hyperglycaemic and alloxan-induced diabetic rats. This effect of the extract was maximum at 400 mg/kg, b.w.
Jafri
M A
MA
Department of Ilmul Advia, Faculty of Medicine (Unani), Jamia Hamdard, -110 062, New Delhi, India.
Aslam
M
M
Javed
K
K
Singh
S
S
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001786:Blood Glucose / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000097:blood*; D005215:Fasting; D005260:Female; D005951:Glucose Tolerance Test; D007004:Hypoglycemic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar; D014044:Tolbutamide / Q000494:pharmacology
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D014044:Tolbutamide