Quantification of siderophore and hemolysin from Stachybotrys chartarum strains, including a strain isolated from the lung of a child with pulmonary hemorrhage and hemosiderosis.
A strain of Stachybotrys chartarum was recently isolated from the lung of a pulmonary hemorrhage and hemosiderosis (PH) patient in Texas (designated the Houston strain). This is the first time that S. chartarum has been isolated from the lung of a PH patient. In this study, the Houston strain and 10 strains of S. chartarum isolated from case (n = 5) or control (n = 5) homes in Cleveland were analyzed for hemolytic activity, siderophore production, and relatedness as measured by random amplified polymorphic DNA analysis.
Vesper
S J
SJ
National Environmental Research Laboratory, U.S. Environmental Protection Agency, Cincinnati, Ohio 45268, USA. Vesper.Stephan@EPA.gov
Dearborn
D G
DG
Elidemir
O
O
Haugland
R A
RA
D000818:Animals; D016022:Case-Control Studies; D002648:Child; D004912:Erythrocytes / Q000378:metabolism; D006460:Hemolysin Proteins / Q000378:metabolism*; D006470:Hemorrhage / Q000382:microbiology; D006486:Hemosiderosis / Q000382:microbiology*; D006801:Humans; D008168:Lung / Q000382:microbiology; D008172:Lung Diseases, Fungal / Q000382:microbiology*; D019105:Random Amplified Polymorphic DNA Technique; D012756:Sheep; D017262:Siderophores / Q000378:metabolism*; D013191:Stachybotrys / Q000235:genetics / Q000302:isolation & purification* / Q000378:metabolism
D006460:Hemolysin Proteins; D017262:Siderophores