Antifungal activity of some tetranortriterpenoids.
Natural tetranortriterpenoids such as cedrelone from Toona ciliata, azadiradione from Azadirachta indica, limonin, limonol and nomilinic acid from Citrus medica, along with some cedrelone derivatives were tested for their antifungal activity against Puccinia arachidis, a groundnut rust pathogen. Results show that cedrelone was the most effective in reducing rust pustule emergence. Replacement of functional groups or modification of the A or the B ring in cedrelone reduced the effectiveness indicating the importance of specific structural features for activity.
Govindachari
T R
TR
Centre for Agrochemical Research, SPIC Science Foundation, 111, Mount Road, 600 032, Madras, India. tuticorigovinda@hotmail.com
Suresh
G
G
Gopalakrishnan
G
G
Masilamani
S
S
Banumathi
B
B
D000935:Antifungal Agents / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D010935:Plant Diseases; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D014315:Triterpenes / Q000494:pharmacology*
D000935:Antifungal Agents; D010936:Plant Extracts; D014315:Triterpenes