title: Ten-year survival in advanced malignant melanoma following treatment with interferon and vindesine.
abstract: A 31-year-old man with malignant melanoma of his right popliteal fossa was treated in 1987 with surgical excision followed by local radiotherapy. Eight months later, he presented with recurrence in the right inguinal lymph nodes, which were resected and followed by radiotherapy to the groin. Ten months later, he developed liver metastases and was treated with vindesine (12 months) and interferon-alpha-2a (30 months) resulting in complete remission which has been maintained for over 10 years. This interesting case report, with brief review of literature, is presented here.
authors.affiliation: Clatterbridge centre for Oncology, Wirral, UK.
authors.forename: M
authors.initials: M
authors.lastname: Iqbal
authors.forename: E
authors.initials: E
authors.lastname: Marshall
authors.forename: J A
authors.initials: JA
authors.lastname: Green
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018572:Disease-Free Survival; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008545:Melanoma / Q000188:drug therapy* / Q000556:secondary*; D012878:Skin Neoplasms / Q000473:pathology*; D014751:Vindesine / Q000627:therapeutic use*
chemical_list: D016898:Interferon-alpha; D014751:Vindesine