title: [Intraoperative hyperpyrexia in patients with osteogenesis imperfecta].
abstract: The aim of this study was to evaluate the influence of different types of anesthesia upon the intra- and postoperative body temperature in osteogenesis imperfecta patients. The development of an intraoperative hyperpyrexia of unknown origin is a typical phenomenon in patients with osteogenesis imperfecta. Body temperatures of up to 40 degrees C are known to complicate the operation. Therefore, in a retrospective study, the pre-, intra- and postoperative body temperature curves of 45 operations under different anaesthesias were measured. Group A underwent a common balanced anaesthesia with the volatile anaesthetic Enfluran in combination with Fentanyl, while group B was operated on under total intravenous anaesthesia (TIVA) with Propofol and Alfentanil. The preoperative temperatures were not different in the two groups. The intraoperative curves showed a constant body core temperature or even an increase under Enfluran, while the temperature always decreased under TIVA. This could be confirmed by intraindividual studies in 5 patients.
authors.affiliation: Orthopädische Klinik und Poliklinik des Klinikum, Johannes Gutenberg-Universität Mainz.
authors.forename: S
authors.initials: S
authors.lastname: Fürderer
authors.forename: A
authors.initials: A
authors.lastname: Stanek
authors.forename: A
authors.initials: A
authors.lastname: Karbowski
authors.forename: A
authors.initials: A
authors.lastname: Eckardt
mesh_terms: D000293:Adolescent; D000769:Anesthesia, Inhalation; D000771:Anesthesia, Intravenous; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007431:Intraoperative Complications / Q000209:etiology*; D008297:Male; D008305:Malignant Hyperthermia / Q000209:etiology*; D010013:Osteogenesis Imperfecta / Q000601:surgery*; D012189:Retrospective Studies; D012307:Risk Factors