title: Potential pitfalls of strain rate imaging: angle dependency.
abstract: Strain Rate Imaging (SRI) is a new echocardiographic technique that allows for the real-time determination of myocardial SR, which may be used for the early and accurate detection of coronary artery disease. We sought to study whether SR is affected by scan line alignment in a computer simulation and an in vivo experiment. Through the computer simulation and the in vivo experiment we generated and validated safe scanning sectors within the ultrasound scan sector and showed that while SRI will be an extremely valuable tool in detecting coronary artery disease there are potential pitfalls for the unwary clinician. Only after accounting for these affects due to angle dependency, can clinicians utilize SRI's potential as a valuable tool in detecting coronary artery disease.
authors.affiliation: Cleveland Clinic Foundation, Department of Cardiology, Ohio 44195, USA.
authors.forename: P L
authors.initials: PL
authors.lastname: Castro
authors.forename: N L
authors.initials: NL
authors.lastname: Greenberg
authors.forename: J
authors.initials: J
authors.lastname: Drinko
authors.forename: M J
authors.initials: MJ
authors.lastname: Garcia
authors.forename: J D
authors.initials: JD
authors.lastname: Thomas
mesh_terms: D000328:Adult; D003198:Computer Simulation; D003327:Coronary Disease / Q000000981:diagnostic imaging; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006321:Heart / Q000503:physiopathology; D006801:Humans; D008297:Male; D008955:Models, Cardiovascular; D013314:Stress, Mechanical