title: Use of Brucella abortus vaccine strain RB51 in pregnant cows after calfhood vaccination with strain 19 in Argentina.
abstract: One hundred and seven pregnant cows, which had been calfhood vaccinated with Brucella abortus strain 19 (S-19) were revaccinated with either S-19 or strain RB51 (S-RB51). All S-19-revaccinated animals seroconverted, while none of the RB51-revaccinated animals seroconverted. Two out of 25 (8%) S-19-revaccinated animals aborted, while none of the 57 RB51-revaccinated group aborted. Four of the S-19-revaccinated animals shed S-19 in the milk for at least 7 days, while only 1 cow shed S-RB51 for at least 3 days (but <7 days) post-parturition. Revaccination of strain 19 calfhood-vaccinated, pregnant cattle with S-RB51 appears to be a safe procedure with no diagnostically negative consequences.
authors.affiliation: Instituto de Patobiología, INTA-CCVyA-CC. 77 Morón, 1708, Buenos Aires, Argentina. Isanma@inta.gov.ar
authors.forename: L E
authors.initials: LE
authors.lastname: Samartino
authors.forename: M
authors.initials: M
authors.lastname: Fort
authors.forename: R
authors.initials: R
authors.lastname: Gregoret
authors.forename: G G
authors.initials: GG
authors.lastname: Schurig
mesh_terms: D000022:Abortion, Spontaneous / Q000517:prevention & control; D000034:Abortion, Veterinary / Q000517:prevention & control*; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D001118:Argentina; D002004:Brucella Vaccine / Q000009:adverse effects / Q000145:classification / Q000276:immunology*; D002003:Brucella abortus / Q000145:classification / Q000276:immunology*; D002007:Brucellosis, Bovine / Q000097:blood / Q000276:immunology / Q000517:prevention & control*; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood / Q000276:immunology / Q000517:prevention & control*; D005260:Female; D011247:Pregnancy; D014611:Vaccination / Q000662:veterinary*; D014613:Vaccines, Attenuated / Q000009:adverse effects / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D002004:Brucella Vaccine; D014613:Vaccines, Attenuated