title: Non-amidine-containing 1,2-dibenzamidobenzene inhibitors of human factor Xa with potent anticoagulant and antithrombotic activity.
authors.affiliation: Lilly Research Laboratories, A Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285, USA. jjm@lilly.com
authors.forename: J J
authors.initials: JJ
authors.lastname: Masters
authors.forename: J B
authors.initials: JB
authors.lastname: Franciskovich
authors.forename: J M
authors.initials: JM
authors.lastname: Tinsley
authors.forename: C
authors.initials: C
authors.lastname: Campbell
authors.forename: J B
authors.initials: JB
authors.lastname: Campbell
authors.forename: T J
authors.initials: TJ
authors.lastname: Craft
authors.forename: L L
authors.initials: LL
authors.lastname: Froelich
authors.forename: D S
authors.initials: DS
authors.lastname: Gifford-Moore
authors.forename: L A
authors.initials: LA
authors.lastname: Hay
authors.forename: D K
authors.initials: DK
authors.lastname: Herron
authors.forename: V J
authors.initials: VJ
authors.lastname: Klimkowski
authors.forename: K D
authors.initials: KD
authors.lastname: Kurz
authors.forename: J T
authors.initials: JT
authors.lastname: Metz
authors.forename: A M
authors.initials: AM
authors.lastname: Ratz
authors.forename: R T
authors.initials: RT
authors.lastname: Shuman
authors.forename: G F
authors.initials: GF
authors.lastname: Smith
authors.forename: T
authors.initials: T
authors.lastname: Smith
authors.forename: R D
authors.initials: RD
authors.lastname: Towner
authors.forename: M R
authors.initials: MR
authors.lastname: Wiley
authors.forename: A
authors.initials: A
authors.lastname: Wilson
authors.forename: Y K
authors.initials: YK
authors.lastname: Yee
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D001549:Benzamides / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D001555:Benzene Derivatives / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D004195:Disease Models, Animal; D015951:Factor Xa / Q000378:metabolism; D065427:Factor Xa Inhibitors; D005343:Fibrinolytic Agents / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D010880:Piperidines / Q000737:chemistry; D011817:Rabbits; D013329:Structure-Activity Relationship; D013927:Thrombosis / Q000517:prevention & control
chemical_list: D000925:Anticoagulants; D001549:Benzamides; D001555:Benzene Derivatives; D065427:Factor Xa Inhibitors; D005343:Fibrinolytic Agents; D010880:Piperidines; D015951:Factor Xa