[Evaluation of MAST-26, newly developed system for the detection of IgE antibodies].
MAST-26 is a new allergy testing system which allows simultaneous determination of allergen-specific IgE antibody levels for 26 allergens using 200 microliters of patient serum. To evaluate the effectiveness of MAST-26 for the detection of allergen-specific IgE antibody, a total of 100 serum samples were collected from allergic patients at five facilities, and allergen-specific IgE antibody was measured by MAST-26. 14% of them were positive to > or = 10 allergens. If the patients had severe allergic symptoms, they were likely to show positive to many allergens. A good correlation was found between the results obtained by MAST-26 with those measured by CAP RAST and by intradermal skin test. It was concluded that MAST-26 is an effective screening method for the detection of allergen-specific IgE.
Nakagawa
T
T
Dept. of Internal Medicine, St. Marianna University School of Medicine.
Komase
Y
Y
Ikezawa
Z
Z
Aihara
M
M
Iwasaki
E
E
Okubo
K
K
Hasegawa
M
M
Akiyama
K
K
Miyamoto
T
T
D000485:Allergens / Q000276:immunology; D000906:Antibodies / Q000097:blood*; D005069:Evaluation Studies as Topic; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis*; D007073:Immunoglobulin E / Q000097:blood*; D012698:Serologic Tests / Q000295:instrumentation*
D000485:Allergens; D000906:Antibodies; D007073:Immunoglobulin E