title: Minor salivary gland secretion in the elderly.
abstract: OBJECTIVE
  Very little information exists on minor salivary gland output (MSGO) in health and disease. We investigated the minor salivary gland output of elderly subjects with different medical backgrounds and the relationship of that output with life practices, demographic variables, complaints of dry mouth, medication usage, functional status, medical treatments, and dental and medical variables.
  
  
  METHODS
  MSGO was measured with a special moisture-detecting paper on the lip, cheek, and palate, which comprised the total MSGO. A parsimonious linear regression model was developed to determine which of the many measured variables influenced the MSGO.
  
  
  RESULTS
  There were significant differences in MSGO between the recruitment sites, with the non-Veteran Affairs (VA) Independent Living participants having significantly lower MSGO than the VA groups. A secretion rate for MSGO based on median values from all subjects of <4.6 microL/min was categorized as being low, whereas a secretion rate for MSGO >/=4.6 microL/min was categorized as high. A regression model was used to examine variables that could be associated with MSGO variability. The results show that being older, a woman, a current smoker, and having a complaint of dry mouth were associated with lower MSGO rates.
  
  
  CONCLUSIONS
  An association between subjective complaints of dry mouth and a decrease in MSGO measured objectively was demonstrated in this elderly population. Furthermore, age and sex effects on MSGO were also demonstrated.
authors.affiliation: University of Pittsburgh, School of Dental Medicine and Graduate School of Public Health, Pittsburgh, PA 15261, USA. wab2+@pitt.edu
authors.forename: W A
authors.initials: WA
authors.lastname: Bretz
authors.forename: W J
authors.initials: WJ
authors.lastname: Loesche
authors.forename: Y M
authors.initials: YM
authors.lastname: Chen
authors.forename: M A
authors.initials: MA
authors.lastname: Schork
authors.forename: B L
authors.initials: BL
authors.lastname: Dominguez
authors.forename: N
authors.initials: N
authors.lastname: Grossman
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D005260:Female; D006760:Hospitalization; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000378:metabolism; D012470:Salivary Glands, Minor / Q000378:metabolism*; D012727:Sex Characteristics; D012959:Socioeconomic Factors