Nifedipine administered in pregnancy: effect on the development of children at 18 months.
The safety of use of the calcium channel blocker nifedipine in pregnancy as it affects child development has not been well evaluated. We report the results, with regard to the safety for children of use of nifedipine in pregnancy, on children followed up at 18 months of age born from women recruited in a study comparing routine treatment with nifedipine compared with no treatment.
Bortolus
R
R
Mario Negri Institute of Pharmacological Research, Milan, Italy.
Ricci
E
E
Chatenoud
L
L
Parazzini
F
F
D002121:Calcium Channel Blockers / Q000009:adverse effects*; D002657:Child Development / Q000187:drug effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D007223:Infant; D009543:Nifedipine / Q000009:adverse effects*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy; D011297:Prenatal Exposure Delayed Effects; D011379:Prognosis
D002121:Calcium Channel Blockers; D009543:Nifedipine