title: Neuroendocrine regulation of gonadotropins in the male and the female.
abstract: For the past decade, neuroendocrinology, in general, and neuroendocrine regulation of reproduction, in particular, were strongly dominated by molecular genetics and molecular endocrinology. In very recent years, however, neuroendocrinology is taking back its place. Beyond doubt GnRH is the neuroendocrine signal for ovulation. But there are still many unexplored pathways within the 'black box' triggering and regulating this signal. Neuroendocrine control of reproduction starts very early in life, well before birth. Hypophyseal gonadotropin secretion is under hypothalamic control at around mid-gestation in the fetal sheep and the fetal pig. These two species could be considered as best-studied farm animals considering neuroendocrinology. This minireview thus will give in the first part a short survey of developmental processes of some of the neuroendocrine systems in the pig and sheep. In the second part, the opioidergic and catecholaminergic control of gonadotropins in adults will be briefly discussed. The last part will focus on the new less known pathways mediating effects on hormones which regulate the reproductive functions.
authors.affiliation: Department of Physiology, Institute for Animal Science and Animal Behaviour (FAL), Neustadt, Germany.
authors.forename: N
authors.initials: N
authors.lastname: Parvizi
mesh_terms: D000375:Aging / Q000502:physiology; D000818:Animals; D005260:Female; D006062:Gonadotropins / Q000502:physiology*; D008297:Male; D009490:Neurosecretory Systems / Q000196:embryology / Q000502:physiology*; D017440:Photoperiod; D012098:Reproduction / Q000502:physiology
chemical_list: D006062:Gonadotropins