Investigation of the child with interstitial lung disease.
Many disorders can affect the pulmonary interstitium in children. Although individual interstitial lung diseases are rare, the range of conditions encountered is wide. Interstitial disease is also seen increasingly as a consequence of the treatment of children having other primary problems including cancer, immunodeficiency and haemotological diseases, as well as in recipients of solid organ and bone marrow transplants. The management and prognosis of individual conditions is highly variable, thus it is essential to search for a precise diagnosis in every patient. High resolution computerised tomography (HRCT) and other less invasive investigations may be helpful in the management of patients. However, it is unusual to be able to make a firm diagnosis without a lung biopsy.
Spencer
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Freeman Hospital, Newcastle upon Tyne, England. D.A. Spencer@ncl.ac.uk
Fall
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D001706:Biopsy; D001992:Bronchoalveolar Lavage Fluid; D002648:Child; D015897:Comorbidity; D006801:Humans; D008168:Lung / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D012129:Respiratory Function Tests