title: [Recurrent abdominal pain and "chronic appendicitis"].
abstract: BACKGROUND
  Chronic appendicitis may be the cause of recurrent abdominal pain. This hypothesis is the subject of controversy. The aim is to clarify the possible existence of a chronic inflammation of the appendix by a clinical and histopathologic study.
  
  
  METHODS
  The case history and the preoperative symptoms and serum findings of 269 patients with appendectomy have been studied. All the appendices have been histologically examined. Chronic appendicitis was diagnosed when at least two typical histological factors of chronic inflammation were present. The histological findings of the appendices have been correlated with preoperative clinical and serum findings of the patients. 14-46 months after the appendectomy, the patients have been examined.
  
  
  RESULTS
  Histological examination revealed 187 cases (69.5%) with acute appendicitis, 44 cases (16.3%) with non disease of appendix and 38 cases (14.2%) with chronic appendicitis. Recurrent abdominal pain and normal leukocyte count were closely correlated (chi 2 = 18.3, p < 0.001; chi 2 = 21.3, p < 0.001 respectively) with diagnosis of chronic appendicitis. 81.8% of 33 patients with chronic appendicitis who underwent follow-up had relief of all the symptoms after appendectomy.
  
  
  CONCLUSIONS
  Therefore, the study seems to confirm the existence of a clinico-pathological condition that can be defined as chronic appendicitis, resolvable with appendectomy.
authors.affiliation: Dipartimento di Discipline Chirurgiche, Università degli Studi, L'Aquila.
authors.forename: S
authors.initials: S
authors.lastname: Leardi
authors.forename: S
authors.initials: S
authors.lastname: Delmonaco
authors.forename: T
authors.initials: T
authors.lastname: Ventura
authors.forename: A
authors.initials: A
authors.lastname: Chiominto
authors.forename: G
authors.initials: G
authors.lastname: De Rubeis
authors.forename: M
authors.initials: M
authors.lastname: Simi
mesh_terms: D015746:Abdominal Pain / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001062:Appendectomy; D001064:Appendicitis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001065:Appendix / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence