title: Cracking the auditory genetic code: part II. Syndromic hereditary hearing impairment.
abstract: OBJECTIVE
  The application of molecular genetic techniques to the study of hereditary hearing impairment has contributed significantly to our understanding of auditory physiology and disease processes. This article reviews the current state of our knowledge regarding the genes associated with syndromic hereditary hearing impairment.
  
  
  METHODS
  Data were obtained from the Medline database and the internet.
  
  
  METHODS
  Articles relevant to genetics of syndromic deafness were selected.
  
  
  METHODS
  Data pertaining to phenotypes, location of genes, identification of genes, and implications for hearing were extracted.
  
  
  CONCLUSIONS
  Significant progress has been made in understanding the molecular pathogenesis of deafness.
authors.affiliation: Epstein Laboratories, Division of Otology, Neurotology, and Skull Base Surgery, University of California San Francisco, 94132-0342, USA.
authors.forename: C J
authors.initials: CJ
authors.lastname: Tseng
authors.forename: A K
authors.initials: AK
authors.lastname: Lalwani
mesh_terms: D015870:Gene Expression / Q000235:genetics; D005815:Genetic Code / Q000235:genetics*; D006309:Hearing / Q000235:genetics*; D006311:Hearing Disorders / Q000235:genetics*; D006801:Humans; D008967:Molecular Biology / Q000379:methods; D013577:Syndrome