Biomechanical measurement of skin distensibility in scleredema of Buschke associated with multiple myeloma.
We report a case of scleredema of Buschke associated with IgG kappa monoclonal hypergammaglobulinaemia. After myeloma polychemotherapy an improvement in skin involvement was observed and confirmed by means of noninvasive skin elasticity measurements. This suggests a relationship between the two diseases. The bioengineering method used can be useful for early detection and monitoring the skin involvement in patients with this disease association.
Grudeva-Popova
J
J
Department of Clinical Haematology and Department of Dermatology, Higher Medical Institute, Plovdiv, Bulgaria.
Dobrev
H
H
D001696:Biomechanical Phenomena; D004548:Elasticity; D005260:Female; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D012592:Scleredema Adultorum / Q000150:complications / Q000473:pathology* / Q000503:physiopathology