Cyclopentene dialdehydes from Tabebuia impetiginosa.
The isolation of two cyclopentene dialdehydes, 2-formyl-5-(4'-methoxybenzoyloxy)-3-methyl-2-cyclopentene-1-acetal dehyde, and 2-formyl-5-(3', 4'-dimethoxybenzoyloxy)-3-methyl-2-cyclopentene-1-acetaldehyde, from the bark of Tabebuia impetiginosa is reported. The structures were established by analysis of spectroscopic data. These compounds showed anti-inflammatory activity.
Koyama
J
J
Kobe Pharmaceutical University, Japan. j-koyama@kobepharma-u.ac.jp
Morita
I
I
Tagahara
K
K
Hirai
K
K
D000447:Aldehydes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D003517:Cyclopentanes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007202:Indicators and Reagents / Q000494:pharmacology; D007962:Leukocytes / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal / Q000737:chemistry*; D013778:Tetrazolium Salts / Q000494:pharmacology; D014197:Trees / Q000737:chemistry*
C412195:2-formyl-5-(3',4'-dimethoxybenzoyloxy)-3-methyl-2-cyclopentene-1-acetaldehyde; C412194:2-formyl-5-(4'-methoxybenzoyloxy)-3-methyl-2-cyclopentene-1-acetaldehyde; D000447:Aldehydes; D000894:Anti-Inflammatory Agents, Non-Steroidal; D003517:Cyclopentanes; D007202:Indicators and Reagents; D013778:Tetrazolium Salts