Functional recovery of respiratory behavior during axonal regeneration in snails (Lymnaea stagnalis) is experience dependent.
This study investigated the role of experience in recovery of pulmonary respiration during axonal regeneration in Lymnaea stagnalis. Pulmonary respiration occurs when snails break the water surface and open the lung orifice, the pneumostome. It was shown that axotomy of all the axons innervating the pneumostome and surrounding area prevents the occurrence of lung respiration in 69% of snails. In the remaining 31%, lung respiration persisted, indicating that peripheral components alone are capable of initiating pneumostome openings and closures. Five weeks postsurgery, all snails with previous nerve crushes showed opening of the pneumostome with normal latency after breaking the water surface. However, prevention of pulmonary respiration during the recovery period dramatically changed the recovered behavior. Thus, experience in pulmonary respiration during axonal regeneration plays a role in the recovery of this behavior.
Hermann
P M
PM
Department of Physiology and Biophysics, University of Calgary, Alberta, Canada.
Wildering
W C
WC
Bulloch
A G
AG
D000818:Animals; D001369:Axons / Q000502:physiology*; D008195:Lymnaea / Q000502:physiology*; D009046:Motor Neurons / Q000502:physiology; D009409:Nerve Crush; D009415:Nerve Net / Q000502:physiology; D009416:Nerve Regeneration / Q000502:physiology*; D012123:Pulmonary Ventilation / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D012683:Sensory Deprivation / Q000502:physiology; D011984:Sensory Receptor Cells / Q000502:physiology*