title: [Adverse reactions to antihypertensive drugs].
abstract: OBJECTIVE
  In chronic therapies, the less number of adverse effects (AE) to drugs is decisive to improve the rate of performance and reach the protective objective. We can make comparisons in the rate of tolerance of antihypertensive drugs (AD) if we study all of them with the same method in patients with real hypertension.
  
  
  METHODS
  Analyzed 922 hospitalized hypertensive patients looking for adverse effects (AE) reported systematically and spontaneously form, the causality must to excel in two algorithms the uncertain grade.
  
  
  RESULTS
  13.47% of antihypertensive drugs presented an AE, beta-blockers presented more AE than diuretics and angiotensin-converting enzyme (ACE) inhibitors.
  
  
  CONCLUSIONS
  The AD haven't the same AE neither feature nor frequency. If to dependent on a poor fulfillment, we lose the protective effectiveness, the application independently of the economic cost isn't right.
authors.affiliation: Servicio de Medicina Interna, Hospital Universitario del Río Hortega, Valladolid.
authors.forename: J C
authors.initials: JC
authors.lastname: Martín Escudero
authors.forename: F
authors.initials: F
authors.lastname: Simal Blanco
authors.forename: F J
authors.initials: FJ
authors.lastname: Mena Martín
authors.forename: D
authors.initials: D
authors.lastname: Arzua Mouronte
authors.forename: L
authors.initials: L
authors.lastname: Marcos Martínez
authors.forename: A
authors.initials: A
authors.lastname: Dueñas Laita
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000009:adverse effects*; D016009:Chi-Square Distribution; D004359:Drug Therapy, Combination; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy; D007407:Interviews as Topic / Q000379:methods; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013030:Spain; D011795:Surveys and Questionnaires
chemical_list: D000959:Antihypertensive Agents