title: Pulsatile release from subcutaneous implants.
abstract: Pulsatile delivery of antigens and hormones from subcutaneous implants could have uses in the animal production and veterinary medicine. Development of single-shot vaccines which release both initial and booster antigen from a single administration and hormonal preparations that release in a similar manner to the natural secretion patterns are two areas with potential. Formulation approaches employed to produce subcutaneous implants with pulsatile release profiles are reviewed.
authors.affiliation: School of Pharmacy, University of Otago, P.O. Box 913, Dunedin, New Zealand
authors.initials: NJ
authors.lastname: Medlicott
authors.initials: IG
authors.lastname: Tucker