Oral lichenoid lesions after hepatitis B vaccination.
The association of mucocutaneous lichen planus and chronic liver disease is widely recognized. The hepatitis B and C viruses have been implicated as being important in this association, although their exact role remains unclear. Recently, lichenoid lesions of the skin after a hepatitis B vaccination have also been reported. In this case, a woman of Southeast Asian origin had lichenoid lesions affecting the oral mucous membranes develop after she was vaccinated against hepatitis B. The lesions appeared 3 weeks after the administration of the third dose of the vaccine and persisted for about 1 year. As the use of the hepatitis B vaccine becomes more widespread, more such cases can be expected to be encountered.
Pemberton
M N
MN
Department of Dental Medicine and Surgery, University Dental Hospital of Manchester, Manchester, England.
Sloan
P
P
Thakker
N S
NS
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001623:Betamethasone / Q000008:administration & dosage; D001706:Biopsy; D005260:Female; D005938:Glucocorticoids; D017325:Hepatitis B Vaccines / Q000009:adverse effects*; D006801:Humans; D017512:Lichenoid Eruptions / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D009059:Mouth Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D009061:Mouth Mucosa / Q000473:pathology; D009067:Mouthwashes / Q000008:administration & dosage; D012074:Remission Induction; D013997:Time Factors; D014614:Vaccines, Synthetic / Q000009:adverse effects*
D000893:Anti-Inflammatory Agents; C075654:Engerix-B; D005938:Glucocorticoids; D017325:Hepatitis B Vaccines; D009067:Mouthwashes; D014614:Vaccines, Synthetic; D001623:Betamethasone