title: Solitary cutaneous metastasis on the buttock: a disclosing sign of pancreatic adenocarcinoma.
abstract: A 48-year-old man, previously healthy and asymptomatic, showed a unique skin lesion located on the right buttock. The histopathological study of the lesion disclosed an adenocarcinoma metastatic to the skin. The primary tumour was found at the head of the pancreas, and was confirmed by biopsy. Six months after the beginning of treatment with Gemcitabine the patient is still asymptomatic, and the cutaneous lesion has disappeared. Carcinomas of the pancreas represent less than 5% of human malignant neoplasms, skin involvement is rare, and metastasis generally multiple and situated in the periumbilical area. To our knowledge, very few patients have been reported with a solitary cutaneous lesion disclosing a pancreatic adenocarcinoma. The atypical location, the absence of related symptoms or analytical disorders, and the good progress of the patient make this case especially interesting.
authors.affiliation: Department of Dermatology, General Hospital of Galicia, Faculty of Medicine, Santiago de Compostela, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Flórez
authors.forename: E
authors.initials: E
authors.lastname: Rosón
authors.forename: D
authors.initials: D
authors.lastname: Sánchez-Aguilar
authors.forename: C
authors.initials: C
authors.lastname: Peteiro
authors.forename: J
authors.initials: J
authors.lastname: Toribio
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000188:drug therapy; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D002081:Buttocks; D003841:Deoxycytidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D012878:Skin Neoplasms / Q000188:drug therapy / Q000556:secondary*; D000093542:Gemcitabine
chemical_list: D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000093542:Gemcitabine