Gene therapy for tissue repair and regeneration.
This review presents a current overview of the discipline of human gene therapy. In addition, a gene therapy method is described in which plasmid genes are transferred from a structural matrix carrier into fresh wound sites so as to enhance tissue repair and regeneration. The potential to develop a gene therapy for bone regeneration is discussed in detail.
Levy
RJ
Children's Hospital of Philadelphia, Abramson Pediatric Research Center, 11th Floor, 34th and Civic Center Blvd., Philadelphia, PA 19104, USA
Goldstein
SA
Bonadio
J