New chemical and biological aspects of S-nitrosothiols.
Nitric oxide (NO) possesses many physiological effects and S-nitrosothiols have been identified in a variety of tissues exhibiting many NO-like activities. This review focuses on the latest discoveries pertaining to the biological functions of S-nitrosothiols and the recent research progress in the chemical properties and biomedical applications of RSNOs.
Wang
K
K
Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.
Zhang
W
W
Xian
M
M
Hou
Y C
YC
Chen
X C
XC
Cheng
J P
JP
Wang
P G
PG
D000818:Animals; D002626:Chemistry, Pharmaceutical; D004563:Electrochemistry; D006801:Humans; D008623:Mercaptoethanol; D015394:Molecular Structure; D009569:Nitric Oxide / Q000378:metabolism*; D009603:Nitroso Compounds / Q000737:chemistry / Q000378:metabolism*; D010396:Penicillamine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D011499:Protein Processing, Post-Translational / Q000502:physiology; D026423:S-Nitroso-N-Acetylpenicillamine; D026403:S-Nitrosothiols; D015290:Second Messenger Systems
D009603:Nitroso Compounds; D026403:S-Nitrosothiols; D009569:Nitric Oxide; D008623:Mercaptoethanol; C032635:S-nitrosomercaptoethanol; D026423:S-Nitroso-N-Acetylpenicillamine; D010396:Penicillamine