Pediatric liver transplantation: the Indian perspective.
Liver transplantation is now the accepted treatment for end stage liver disease, hepatic-based inborn errors of metabolism and localised primary hepatic malignancies. In children the commonest indication is biliary atresia. Innovations in surgical techniques, particularly liver reductions/splits and living related transplants have not only shortened the waiting period but have improved the results of surgery as well. The long term survival for pediatric liver transplant recipients in most large series from the Western world is more than 85%. Treatment protocols for ITU care of donors and recipients, anaesthetic care during surgery and post-operative immunosuppression are available. A country like India has a crying need for the development of facilities for liver transplantation in children but a number of factors have hampered the progress. The cost of surgery and post-operative immunosuppression and attitudes on life and death issues have been the greatest impediment. A few organisational details have also to be addressed to in order to minimise interdepartmental clashes of interest. It is hoped that a viable programme would soon be available for the children in India.
Bhatnagar
V
V
Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D005544:Forecasting; D006801:Humans; D007165:Immunosuppression Therapy; D007194:India; D007223:Infant; D007231:Infant, Newborn; D017093:Liver Failure / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D019520:Living Donors