[Treatment of ectopic pregnancy in 2000].
Operative laparoscopy is currently the best treatment for pregnancy (EP). As with laparotomy, laparoscopic treatment of EP can be either conservative (salpingotomy or radical (salpingectomy). After conservative laparoscopic treatment, failures are diagnosed by monitoring the drop in beta-hCG levels. Fertility results after laparoscopic treatment of EP are comparable with those observed after similar treatment by laparotomy. Better knowledge o the risk factors of EP, development of hCG assays using serum progesterone and high resolution sonography using vaginal probes allow early diagnosis of EP and a nonsurgical approach in more than 30% of cases. When inclusion criteria are strict, methotrexate administered by local injection or systemically (1mg/kg) in a single dose or in combination with mifepristone gives a 90 to 95% success rate. Whatever treatment protocol is used, fertility prognosis after EP is not correlated to the features of EP but depends mainly on patient age and past history.
Chapron
C
C
Service de Gynécologie-Obstétrique (Pr Dubuisson), Clinique Universitaire Baudelocque, CHU Cochin Saint-Vincent de Paul, Paris.
Fernandez
H
H
Dubuisson
J B
JB
D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D017211:Treatment Failure
D018997:Chorionic Gonadotropin, beta Subunit, Human; D008727:Methotrexate