Antibiotic secondary metabolites of Dichotomomyces cejpii.
Nine fungal strains of Dichotomomyces cejpii were studied for their ability to produce antibiotic metabolites. It was found that they produced secondary exo- and endometabolites with antimicrobial activity against Gram-negative and Gram-positive bacteria, yeasts and moulds and with a toxic effect against animal organs in vitro. Detailed chemical characterization of these active principles need to be carried out.
Piecková
E
E
Institute of Preventive and Clinical Medicine, Bratislava, Slovakia. pieckova@upkm.sk
Roeijmans
H
H
D000818:Animals; D000900:Anti-Bacterial Agents / Q000378:metabolism* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002645:Chickens; D002855:Chromatography, Thin Layer; D002923:Cilia / Q000187:drug effects; D005658:Fungi / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D009924:Organ Culture Techniques; D014132:Trachea / Q000187:drug effects
D000900:Anti-Bacterial Agents