title: Perspective: The insulin signaling system--a common link in the pathogenesis of type 2 diabetes.
authors.affiliation: Department of Metabolic Medicine, Imperial College School of Medicine, London, United Kingdom.
authors.forename: D J
authors.initials: DJ
authors.lastname: Withers
authors.forename: M
authors.initials: M
authors.lastname: White
mesh_terms: D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007328:Insulin / Q000502:physiology*; D055504:Insulin Receptor Substrate Proteins; D007334:Insulin-Like Growth Factor I / Q000502:physiology; D047908:Intracellular Signaling Peptides and Proteins; D007515:Islets of Langerhans / Q000503:physiopathology; D010750:Phosphoproteins / Q000502:physiology; D011972:Receptor, Insulin / Q000502:physiology; D015398:Signal Transduction
chemical_list: C526292:IRS1 protein, human; C526297:IRS2 protein, human; D007328:Insulin; D055504:Insulin Receptor Substrate Proteins; D047908:Intracellular Signaling Peptides and Proteins; D010750:Phosphoproteins; D007334:Insulin-Like Growth Factor I; D011972:Receptor, Insulin