Menopause and colorectal cancer.
Post-menopausal women who have never used hormone replacement therapy have a higher risk of colon, but not rectal, cancer than do premenopausal women of the same age, socio-cultural class and dietary habits. Such risk increase seems to last about 10 years and to be restricted to lean women, a group who have lower levels of oestradiol after ovarian function ceases after menopause.
Franceschi
S
S
Servizio di Epidemiologia, Centro di Riferimento Oncologico, Aviano (PN), Italy.
Gallus
S
S
Talamini
R
R
Tavani
A
A
Negri
E
E
La Vecchia
C
C
D003110:Colonic Neoplasms / Q000453:epidemiology*; D016001:Confidence Intervals; D005260:Female; D020249:Hormone Replacement Therapy; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D016017:Odds Ratio; D012004:Rectal Neoplasms / Q000453:epidemiology*; D012307:Risk Factors