title: [Analysis of the association between the T113M polymorphism of the human il-9 gene and bronchial asthma].
abstract: The T113M polymorphism resulting from the missense mutation in exon 5 of the human interleukin 9 (IL9) gene was tested for association with bronchial asthma (BA). The genotype frequency analysis did not reveal a deviation from the Hardy-Weinberg equilibrium. A comparison of the genotype frequency distributions in a control group of healthy individuals and in patients with BA suggested an association between T113M and the clinical phenotype. However, this association was not confirmed by the affected family-based association control (AFBAC) or the transmission/disequilibrium test (TDT).
authors.affiliation: Institute of Medical Genetics, Tomsk Research Center, Russian Academy of Medical Sciences, Russia.
authors.forename: M B
authors.initials: MB
authors.lastname: Freĭdin
authors.forename: V P
authors.initials: VP
authors.lastname: Puzyrev
authors.forename: L M
authors.initials: LM
authors.lastname: Ogorodova
authors.forename: O A
authors.initials: OA
authors.lastname: Saliukova
authors.forename: E M
authors.initials: EM
authors.lastname: Kamaltynova
authors.forename: I M
authors.initials: IM
authors.lastname: Kulmanakova
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Petrovskaia
mesh_terms: D000483:Alleles; D001249:Asthma / Q000235:genetics*; D006801:Humans; D016906:Interleukin-9 / Q000235:genetics*; D011110:Polymorphism, Genetic
chemical_list: D016906:Interleukin-9