[A case of Sipple syndrome whose bilateral pheochromocytomas were resected separately after a 3-year interval].
A 23-year-old woman who had undergone total thyroidectomy and parabronchial lymphadenectomy at the Department of Otolaryngology in our hospital was suspected to have a thyroid carcinoma. Histological examination revealed a medullary carcinoma of the thyroid and normal parathyroid glands. Because a computed tomographic scan after surgery revealed a tumor of the left adrenal gland, the patient was examined at our department two months after the thyroidectomy, 1994. Endocrinic examinations and 123I-MIBG scintigraphy revealed a left adrenal pheochromocytoma of Sipple syndrome. She then underwent left adrenalectomy. Histological diagnosis was pheochromocytoma of the left adrenal gland. Three years after the surgery, a right adrenal tumor was detected by computed tomography. Although results of endocrine examinations were normal, 131I-MIBG scintigraphy showed a hot spot in the right adrenal gland. Right adrenal pheochromocytoma was diagnosed 3 years after surgery for a contralateral adrenal pheochromocytoma. Although surgery was recommended, the patient consented to right adrenalectomy, 1 year later after marriage and before becoming pregnant. Histological examination of the resected specimen revealed pheochromocytoma of the right adrenal gland.
Kimura
T
T
Department of Urology, Jikei University School of Medicine.
Ikemoto
I
I
Furuta
N
N
Ohishi
Y
Y
D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D000315:Adrenalectomy; D000328:Adult; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D018813:Multiple Endocrine Neoplasia Type 2a / Q000601:surgery*; D010673:Pheochromocytoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D013997:Time Factors