[L-dopa effective parkinsonism appeared after shunt revision of the aqueductal stenosis: report of two cases].
We present a two cases of parkinsonism that appeared after shunt revision in obstructive hydrocephalus patients. Case 1 was a 59-year-old man and case 2 was a 32-year-old woman. Parkinsonism appeared in both cases after 3 or 4 shunt revisions within a period of three months. Treatment with bromocriptine, amantadine and L-dops had no effect, but the parkinsonism dramatically improved with administration of L-dopa. It was thought that repeated dilatation and collapse of the third ventricle in a short period of time might have caused concussion of the nigrostriatal pathway, resulting in reversible function loss of the nigrostriatal pathway.
Ochiai
H
H
Department of Neurosurgery, Miyazaki Prefectural Hospital, Japan.
Yamakawa
Y
Y
Miyata
S
S
Kawasoe
T
T
D000328:Adult; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D002535:Cerebral Aqueduct / Q000473:pathology*; D003251:Constriction, Pathologic / Q000150:complications; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000601:surgery*; D007980:Levodopa / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy* / Q000209:etiology; D011183:Postoperative Complications / Q000188:drug therapy* / Q000209:etiology; D017287:Ventriculoperitoneal Shunt
D000978:Antiparkinson Agents; D007980:Levodopa