Quaternary indole alkaloids from the stem bark of Strychnos guianensis.
Two new quaternary alkaloids, 9-methoxy-Nb-methylgeissoschizol and guiachrysine together with the known compounds C-alkaloid O, fluorocurine, mavacurine, macusine B and C-profluorocurine, were isolated from Strychnos guianensis stembark. The structures of the compounds were elucidated on the basis of spectroscopic studies.
Penelle
J
J
Université de Liège, Institut de Pharmacie, CHU, Belgium. jacques.penelle@ulg.ac.be
Tits
M
M
Christen
P
P
Molgo
J
J
Brandt
V
V
Frédérich
M
M
Angenot
L
L
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D000818:Animals; D066298:In Vitro Techniques; D007211:Indoles / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D008564:Membrane Potentials / Q000187:drug effects; D051379:Mice; D009465:Neuromuscular Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D009469:Neuromuscular Junction / Q000187:drug effects / Q000502:physiology; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011898:Ranidae; D013020:South America
C412061:9-methoxy-Nb-methylgeissoschizol; D000470:Alkaloids; D007211:Indoles; D009465:Neuromuscular Agents; C412062:guiachrysine