title: Functional magnetic stimulation facilitates gastrointestinal transit of liquids in rats.
abstract: The purpose of this study was to investigate the effect of a relatively novel technology, functional magnetic stimulation (FMS), on gastrointestinal transit of liquids in rats. Orogastric gavage with technetium-99 solution was used to assess gastric emptying and gastrointestinal transit time in 92 rats. FMS was performed over the anterior cervical and/or dorsal thoracolumbar regions using a figure-8 coil. Stimulation protocols were 1, 2, or 4 h in length. FMS accelerated gastric emptying and decreased gastrointestinal transit time. The acceleration was dependent on the stimulation parameters used as well as on the duration of the protocol; high levels of FMS produced a quicker effect, whereas lower levels were effective at later times. This study provides evidence that FMS could be an alternative or adjunct therapy to treat disorders in gastrointestinal motility.
authors.affiliation: Spinal Cord Injury Center, VA Long Beach Health Care System, Long Beach, CA 90822, USA. vernom.lin@med.va.gov
authors.forename: V W
authors.initials: VW
authors.lastname: Lin
authors.forename: I
authors.initials: I
authors.lastname: Hsiao
authors.forename: H
authors.initials: H
authors.lastname: Xu
authors.forename: T
authors.initials: T
authors.lastname: Bushnik
authors.forename: I
authors.initials: I
authors.lastname: Perkash
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D004326:Drinking; D004558:Electric Stimulation; D005746:Gastric Emptying / Q000502:physiology*; D005751:Gastric Lavage; D005769:Gastrointestinal Motility / Q000502:physiology; D008160:Lumbosacral Plexus / Q000502:physiology; D008280:Magnetics; D051381:Rats; D017207:Rats, Sprague-Dawley; D013116:Spinal Cord / Q000502:physiology*; D013270:Stomach / Q000294:innervation / Q000502:physiology; D013667:Technetium
chemical_list: D013667:Technetium