Chromosomal localization of the genes encoding ALDH, BMP-2, R-FABP, IFN-gamma, RXR-gamma, and VIM in chicken by fluorescence in situ hybridization.
Six structural genes encoding ALDH, BMP-2, R-FABP, IFN-gamma, RXR-gamma and VIM were mapped in the chicken by fluorescence in situ hybridization (FISH) using genomic and cDNA clones as probes. The genes were found to be located on four different macrochromosomes: chromosome 1 (IFNG and FABP), chromosome 2 (VIM and ALDH), chromosome 3 (BMP2) and a smaller macrochromosome, most probably chromosome 7 (RXRG). With the exception of IFNG none of the newly mapped sites corresponds to known orthologous regions between chicken and human chromosomes.
Guttenbach
M
M
Department of Human Genetics, University of Würzburg, Biozentrum, Germany.
Nanda
I
I
Brickell
P M
PM
Godbout
R
R
Staeheli
P
P
Zehner
Z E
ZE
Schmid
M
M
D000444:Aldehyde Dehydrogenase / Q000235:genetics; D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000235:genetics; D002352:Carrier Proteins / Q000235:genetics; D002645:Chickens / Q000235:genetics*; D002871:Chromosome Banding; D017124:Conserved Sequence / Q000235:genetics; D019143:Evolution, Molecular; D000071438:Fatty Acid-Binding Protein 7; D050556:Fatty Acid-Binding Proteins; D005796:Genes / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007371:Interferon-gamma / Q000235:genetics; D018996:Myelin P2 Protein / Q000235:genetics; D009363:Neoplasm Proteins; D020161:Physical Chromosome Mapping; D018168:Receptors, Retinoic Acid / Q000235:genetics; D047488:Retinoid X Receptors; D014157:Transcription Factors / Q000235:genetics; D025521:Tumor Suppressor Proteins; D014746:Vimentin / Q000235:genetics
D019485:Bone Morphogenetic Proteins; D002352:Carrier Proteins; C107608:FABP7 protein, human; D000071438:Fatty Acid-Binding Protein 7; D050556:Fatty Acid-Binding Proteins; D018996:Myelin P2 Protein; D009363:Neoplasm Proteins; D018168:Receptors, Retinoic Acid; D047488:Retinoid X Receptors; D014157:Transcription Factors; D025521:Tumor Suppressor Proteins; D014746:Vimentin; D007371:Interferon-gamma; D000444:Aldehyde Dehydrogenase