title: Blood cells and plasma proteins of chickens fed a diet supplemented with (1-->3),(1-->6)-beta-D-glucan and enrofloxacin.
abstract: The effects of (1-->3),(1-->6)-beta-D-glucan from Saccharomyces cerevisiae and of the fluochinolone enrofloxacin were studied on red and white blood cells and plasma proteins of growing chickens up to the 35th day of life. The prominent findings within the leukocyte population on a per cent scale are: (i) increase of leukocyte count; increase of neutrophils and decrease of lymphocytes in the control and in the antibiotic group from day 17 to day 35; (ii) a minor decrease of neutrophils and no change of lymphocytes in the glucan group; (iii) the monocytes increase from 2.5 +/- 1.8% to 6.5 +/- 7.6% in the glucan group; (iv) the basophils increase in the control group and scale down in the other groups from day 17 to day 35. The total count of leukocytes increases in the controls and in the glucan group. The total protein content of blood plasma, beta-globulin and gamma-globulin increase and the albumin-globulin-ratio and alpha-globulin decline during chickens growth. These changes are most prominent in the glucan group. The haemoglobin concentration shows in all three dietary groups a highly significant increase from day 17 to day 35 by about 17 to 27 per cent; no changes are seen in packed cell volume and number of erythrocytes per litre blood.
authors.affiliation: Institut für Lebensmitteltechnologie I, Fachgebiet Prozesstechnische Grundlagen der Lebensmitteltechnologie, Fachbereich Lebensmittelwissenschaft und Biotechnologie, Technische Universität Berlin, Germany. L.-G.Fleischer@gmx.de
authors.forename: L G
authors.initials: LG
authors.lastname: Fleischer
authors.forename: G
authors.initials: G
authors.lastname: Gerber
authors.forename: R W
authors.initials: RW
authors.lastname: Liezenga
authors.forename: E
authors.initials: E
authors.lastname: Lippert
authors.forename: M A
authors.initials: MA
authors.lastname: Scholl
authors.forename: G
authors.initials: G
authors.lastname: Westphal
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001773:Blood Cells / Q000737:chemistry / Q000166:cytology / Q000187:drug effects*; D001798:Blood Proteins / Q000032:analysis* / Q000187:drug effects; D002645:Chickens / Q000097:blood* / Q000254:growth & development / Q000502:physiology; D000077422:Enrofloxacin; D004906:Erythrocyte Count / Q000662:veterinary; D024841:Fluoroquinolones; D005936:Glucans / Q000008:administration & dosage / Q000494:pharmacology*; D006400:Hematocrit / Q000662:veterinary; D006454:Hemoglobins / Q000032:analysis; D007958:Leukocyte Count / Q000662:veterinary; D016131:Lymphocyte Subsets / Q000187:drug effects; D015363:Quinolones / Q000008:administration & dosage / Q000494:pharmacology*; D012709:Serum Albumin / Q000032:analysis; D012712:Serum Globulins / Q000032:analysis
chemical_list: D000890:Anti-Infective Agents; D001798:Blood Proteins; D024841:Fluoroquinolones; D005936:Glucans; D006454:Hemoglobins; D015363:Quinolones; D012709:Serum Albumin; D012712:Serum Globulins; D000077422:Enrofloxacin