title: Indicanines B and C, two isoflavonoid derivatives from the root bark of Erythrina indica.
abstract: In addition to two known compounds, 5,4'-di-O-methylalpinumisoflavone and cajanin, a new 3-phenylcoumarin metabolite, named indicanine B, and a new isoflavone derivative, named indicanine C, were isolated from the root bark of Erythrina indica. By means of spectroscopic analysis, the structures of the new compounds were characterized as 4-hydroxy-3-(4'-hydroxyphenyl)-5-methoxy-2",2"-dimethylpyrano [5",6":6,7] coumarin and 4'-hydroxy-5-methoxy-2",2"-dimethylpyrano [5",6":6,7] isoflavone, respectively. The 13C-NMR data of cajanin and the in vitro antimicrobial spectrum and potencies of the isolated compounds are also reported.
authors.affiliation: Department of Organic Chemistry, University of Yaounde I, Cameroon.
authors.forename: A K
authors.initials: AK
authors.lastname: Waffo
authors.forename: G A
authors.initials: GA
authors.lastname: Azebaze
authors.forename: A E
authors.initials: AE
authors.lastname: Nkengfack
authors.forename: Z T
authors.initials: ZT
authors.lastname: Fomum
authors.forename: M
authors.initials: M
authors.lastname: Meyer
authors.forename: B
authors.initials: B
authors.lastname: Bodo
authors.forename: F R
authors.initials: FR
authors.lastname: van Heerden
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004895:Erythrina / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D009161:Mycobacterium / Q000187:drug effects; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D003374:Coumarins; D007529:Isoflavones; C412072:indicanine B; C412071:indicanine C