title: [Usefulness of bone densitometry in the evaluation of primary hyperparathyroidism].
abstract: BACKGROUND
  In recent years, the clinical profile of primary hyperparathyroidism (PH) is predominantly characterized by mild or asymptomatic forms. In this context, the effects of the PH on bone metabolism reach a growing importance in the adoption of therapeutic decisions.
  
  
  METHODS
  116 patients with PH were studied, 95 women (25 premenopausal, 70 postmenopausal) and 21 males. In all cases parathyroidectomy criteria were evaluated. Bone mineral density (BMD) was determined in 71 patients in lumbar spine (LS) and femoral neck by dual-X-Ray absorptiometry (DXA) and the influence of this measurement in the decision of surgical treatment was analyzed.
  
  
  RESULTS
  The patients with PH showed a significant reduction of BMD at all sites (p < 0.001) and 71.8% met osteoporosis densitometric criteria. The most frequent parathyroidectomy criteria was the presence of specific clinical manifestations (51.7%) followed by decrease of the BMD in LS (49.3%). The probability of meeting criteria for surgical treatment was significantly higher in patients in which BMD was measured (odds ratio: 3.09 [1.03-9.22]; p = 0.036).
  
  
  CONCLUSIONS
  In its current presentation, PH presents a significant decrease of bone mass. The systematic performance of bone densitometry has a decisive influence in its appropriate management.
authors.affiliation: Servicio de Endocrinología y Nutrición (Unidad de Metabolismo Oseo), Hospital Clínico San Cecilio, Granada. mmt@jet.es
authors.forename: M
authors.initials: M
authors.lastname: Muñoz-Torres
authors.forename: M
authors.initials: M
authors.lastname: Ventosa Viñas
authors.forename: P
authors.initials: P
authors.lastname: Mezquita Raya
authors.forename: V
authors.initials: V
authors.lastname: Luna
authors.forename: F
authors.initials: F
authors.lastname: López Rodríguez
authors.forename: D
authors.initials: D
authors.lastname: Becerra
authors.forename: M
authors.initials: M
authors.lastname: Quesada Charneco
authors.forename: F
authors.initials: F
authors.lastname: Escobar Jiménez
authors.forename: J
authors.initials: J
authors.lastname: Jiménez Moleón
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D000367:Age Factors; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000175:diagnosis; D005260:Female; D005272:Femur Neck; D006801:Humans; D006961:Hyperparathyroidism / Q000175:diagnosis* / Q000601:surgery; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D010024:Osteoporosis / Q000175:diagnosis; D016105:Parathyroidectomy; D017698:Postmenopause; D012737:Sex Factors