[Structural regularities in activated cleavage sites of thrombin receptors].
Comparison of thrombin receptors activation splitting sites sequences testifies to their similarity both in activation splitting sites of protein precursors and protein proteinase inhibitors reactive sites. In all these sites corresponded to effectory sites P2'-positions are placed by hydrophobic amino-acids only. The regularity defined conforms with previous thesis about the role of effectory S2'-site in regulation of the processes mediated by serine proteinases.
Mikhaĭlik
I V
IV
O.V. Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv.
Verevka
S V
SV
D000595:Amino Acid Sequence; D006868:Hydrolysis; D008969:Molecular Sequence Data; D018179:Receptors, Thrombin / Q000737:chemistry / Q000378:metabolism*
D018179:Receptors, Thrombin