Mouse as the measure of man?
The humble house mouse's cohabitation with humans has been noted since the birth of agriculture, about 10 000 years ago, in the fertile flood plains of the Middle East. In recent times, however, the mouse has been elevated from pest to model for the study of human health and disease. Recent genomics and genetics initiatives will ensure the continued growth of the house mouse as a disease model.
Denny
P
P
MRC UK Mouse Genome Centre and Mammalian Genetics Unit, Harwell, Oxfordshire, UK. p.denny@har.mrc.ac.uk
Justice
M J
MJ
D000818:Animals; D003628:Database Management Systems; D004195:Disease Models, Animal; D016678:Genome; D006801:Humans; D051379:Mice; D008817:Mice, Mutant Strains