title: Spinal nephroblastoma in an Irish wolfhound.
abstract: A 1-year-old Irish wolfhound was presented with a history of slowly progressive left pelvic limb paresis. A neurological examination demonstrated bilateral deficits referable to the thoracolumbar spinal cord. Lumbar cerebrospinal fluid contained neoplastic cells. An intradural, extramedullary mass was demonstrated by myelography at the caudal aspect of T13. Surgical excision was abandoned owing to severe macroscopic damage to, and apparent infiltration of, the cord, and the dog was euthanased. The tumour was diagnosed histologically as an extrarenal nephroblastoma. Nephroblastoma should be suspected in young, large-breed dogs with intradural extramedullary masses over spinal segments T10-L2. The prognosis for complete recovery after surgical excision is guarded to poor.
authors.affiliation: Department of Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
authors.forename: T
authors.initials: T
authors.lastname: Vaughan-Scott
authors.forename: J
authors.initials: J
authors.lastname: Goldin
authors.forename: J W
authors.initials: JW
authors.lastname: Nesbit
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D004285:Dogs; D017809:Fatal Outcome; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D009192:Myelography / Q000662:veterinary; D011379:Prognosis; D013120:Spinal Cord Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D009396:Wilms Tumor / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*