Sorting and transport in C. elegans: aA model system with a sequenced genome.
In the past few years, yeast and cultured cells have been the model systems of choice for the study of protein sorting and transport. Recently, there has been a surge in research in these areas in Caenorhabditis elegans, with advances in experimental techniques and genomics. New in vivo assays that monitor endocytosis and neuronal transport have been used to delineate roles for several genes in these processes.
Koushika
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Department of Anatomy and Neurobiology, Box 8108, 660 South Euclid Avenue, Washington University School of Medicine, St. Louis, MO 63110, USA. sandhya@thalamus.wustl.edu.
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D000818:Animals; D001692:Biological Transport / Q000235:genetics; D017173:Caenorhabditis elegans / Q000235:genetics* / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D003712:Dendrites / Q000378:metabolism; D004398:Dyneins / Q000378:metabolism; D004705:Endocytosis / Q000502:physiology; D017238:Genes, Helminth; D016547:Kinesins / Q000378:metabolism; D008957:Models, Genetic; D009475:Neurons, Afferent / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism
D011956:Receptors, Cell Surface; D004398:Dyneins; D016547:Kinesins