title: Topical tretinoin and 5-fluorouracil in the treatment of linear verrucous epidermal nevus.
abstract: Treatment of a linear verrucous epidermal nevus using topical 0.1% tretinoin cream and 5% 5-fluorouracil in a young patient is described. In 1994, successful topical therapy using this combination was described in the management of an inflammatory linear verrucous epidermal nevus. We report another case in which treatment of a noninflamed epidermal verrucous nevus with 0.1% tretinoin and 5% 5-fluorouracil resulted in significant improvement. An updated summary of the literature discussing management of epidermal nevi is presented.
authors.affiliation: Department of Dermatology, Henry Ford Health System, Detroit, MI 48202, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Kim
authors.forename: M W
authors.initials: MW
authors.lastname: Chang
authors.forename: T
authors.initials: T
authors.lastname: Shwayder
mesh_terms: D000963:Antimetabolites / Q000627:therapeutic use*; D002648:Child; D004338:Drug Combinations; D005472:Fluorouracil / Q000627:therapeutic use*; D006222:Hamartoma / Q000188:drug therapy*; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008297:Male; D012871:Skin Diseases / Q000188:drug therapy*; D014212:Tretinoin / Q000627:therapeutic use*
chemical_list: D000963:Antimetabolites; D004338:Drug Combinations; D007641:Keratolytic Agents; D014212:Tretinoin; D005472:Fluorouracil