title: [Early prognosis in chronic subdural hematomas. Multivariate analysis of 137 cases].
abstract: BACKGROUND
  In the literature there is evidence relating different factors such as age and preoperative clinical condition with prognosis in patients treated surgically for chronic subdural haematoma.
  
  
  OBJECTIVE
  To clarify and quantify the magnitude of the factors which determine early prognosis (during hospital admission) of these patients.
  
  
  METHODS
  We made a prospective study of 137 patients who had been operated on in our centre and found the relationship between different clinical and therapeutic variables with the clinical course and morbidity-mortality by means of multivariate and survival analysis.
  
  
  RESULTS
  A high Markwalder functional score (3-4) is an independent factor of poor prognosis (OR = 13.15; CI 95% 6.1-28.4; p = 0.01), as is the presence of a coexisting coagulopathy (OR = 27.2; CI 95% 9.3-79.5; p = 0.01). Advanced age tended to increase the risk (OR = 1.104) but did not reach statistical significance (p = 0.0654). A multivariate logistic model, which included the functional score and presence of coagulopathy, correctly classified 94.7% of the cases studied. Analysis of survival showed two groups with different early mortality as a function of the Markwalder score (high: 3-4 and low: 0-1-2), which could be differentiated statistically (Log-Rank chi squared test: 3.95; p = 0.0468).
  
  
  CONCLUSIONS
  The preoperative clinical state classified by functional scores and the presence of underlying coagulopathy are the main prognostic factors in chronic subdural haematoma during hospital admission. Advanced age is probably not in itself an independent factor for bad prognosis.
authors.affiliation: Servicio de Neurocirugía, Hospital General Universitario Gregorio Marañón, Madrid, España.
authors.forename: P D
authors.initials: PD
authors.lastname: Delgado
authors.forename: F J
authors.initials: FJ
authors.lastname: Cogolludo
authors.forename: O
authors.initials: O
authors.lastname: Mateo
authors.forename: P
authors.initials: P
authors.lastname: Cancela
authors.forename: R
authors.initials: R
authors.lastname: García
authors.forename: R
authors.initials: R
authors.lastname: Carrillo
mesh_terms: D000368:Aged; D002908:Chronic Disease; D018450:Disease Progression; D006408:Hematoma, Subdural / Q000401:mortality / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D012189:Retrospective Studies; D012720:Severity of Illness Index; D015996:Survival Rate
vernacular_title: Pronóstico precoz en hematomas subdurales crónicos. Análisis multivariante de 137 casos.