Steroid-sensitive nephrotic syndrome associated with Kimura disease.
We report an 11-year-old Japanese boy with Kimura disease and associated nephrotic syndrome. Before the diagnosis of Kimura disease was established, the patient had three episodes of swelling on the left cheek with subsequent nephrotic syndrome. Steroids were effective for both conditions. However, both conditions recurred within months of discontinuation of steroids. For the fourth episode of swelling on the left cheek, cyclosporine (CsA) was used. The subcutaneous tumor responded to CsA and disappeared within a few days. There has been no subsequent relapse of the nephrotic syndrome to date.
Nakahara
C
C
Department of Pediatrics, Tsukuba University Hospital, University of Tsukuba, Ibaraki, Japan. Chico@md.tsukuba.ac.jp
Wada
T
T
Kusakari
J
J
Kanemoto
K
K
Kinugasa
H
H
Sibasaki
M
M
Nagata
M
M
Matsui
A
A
D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002648:Child; D016572:Cyclosporine / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D012008:Recurrence; D013256:Steroids / Q000627:therapeutic use*
D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D013256:Steroids; D016572:Cyclosporine; D011239:Prednisolone