title: Comparison of whole body and segmental bioimpedance methodologies for estimating total body water.
abstract: We compared the whole body (WB) and segmental bioelectrical impedance analysis (BIA) methodologies in a group of healthy adults (n = 25). It has been suggested that the segmental methodology may overcome the difficulty in generating a single algorithm to predict total body water (TBW) in all groups whether healthy or not. We measured TBW, using D2O dilution, and WB and segmental BIA parameters. Cole-Cole analysis was used to determine the impedance at the characteristic frequency (Zc). The correlation between TBW (by D2O dilution) and segmental BIA measures (multiple regression, r = 0.90, p < 0.001, SEE = 3.1 L) was not significantly higher than the correlation between TBW (D2O dilution) and WB BIA measures (simple regression, r = 0.85, p < 0.001, SEE = 3.6 L). Others have observed this "lack of improvement" in a group of healthy subjects. The true value of the segmental BIA methodology may lie in applications involving groups with altered distributions of segmental and compartmental fluid.
authors.affiliation: Department of Paediatrics and Child Health, University of Queensland, Royal Children's Hospital, Brisbane, Australia.
authors.forename: M J
authors.initials: MJ
authors.lastname: Wotton
authors.forename: B J
authors.initials: BJ
authors.lastname: Thomas
authors.forename: B H
authors.initials: BH
authors.lastname: Cornish
authors.forename: L C
authors.initials: LC
authors.lastname: Ward
mesh_terms: D000328:Adult; D000465:Algorithms; D001823:Body Composition; D015992:Body Mass Index; D001834:Body Water; D001835:Body Weight; D017097:Electric Impedance; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D012044:Regression Analysis; D012727:Sex Characteristics