Interpretation and diagnostic implications of an immunoblotting (INNOLIA) test for HCV serology.
The association analysis of antibodies versus HCV, carried out with INNOLIA test, prevented a clear determination of the existence of specific serological patterns. In this respect, it may be of interest to monitor the immune response to the non-structural genomic regions (NS3, NS4, NS5). The INNOLIA kit is reliable, but susceptible to improvement in terms of specificity, sensitivity and biological standardization.
Ravera
G
G
USL 3 Genovese Clinical Pathology Department, University of Genoa.
Franceschini
M
M
Monacelli
R
R
Bottaro
L C
LC
Colombi
T
T
Specchia
C
C
D006526:Hepatitis C / Q000175:diagnosis*; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D015151:Immunoblotting / Q000379:methods* / Q000592:standards; D011933:Reagent Kits, Diagnostic; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric
D018937:Hepatitis C Antibodies; D011933:Reagent Kits, Diagnostic