title: Enthalpies of solution of ampicillin, amoxycillin and their binary mixtures at 310.15 K.
abstract: Enthalpies of solutions of ampicillin, amoxycillin and their binary mixtures have been determined at pH 2, 5, and 7 using C-80 calorimeter. The systems showed endothermic behaviour; molar enthalpies of solutions of ampicillin were determined to be 13.32, 15.89 and 23.21 kJ mol(-1) and amoxycillin were 16.32, 18.45 and 26. 25 kJ mol(-1) at pH 2, 5, and 7, respectively. The excess molar enthalpies of solution have also been calculated to find any interaction between these two drugs.
authors.affiliation: University Institute of Pharmaceutical Sciences, Punjab University, 160014, Chandigharh, India.
authors.forename: D V
authors.initials: DV
authors.lastname: Jain
authors.forename: N
authors.initials: N
authors.lastname: Kashid
authors.forename: S
authors.initials: S
authors.lastname: Kapoor
authors.forename: R
authors.initials: R
authors.lastname: Chadha
mesh_terms: D000658:Amoxicillin / Q000737:chemistry*; D000667:Ampicillin / Q000737:chemistry*; D002151:Calorimetry; D002626:Chemistry, Pharmaceutical; D004338:Drug Combinations; D006863:Hydrogen-Ion Concentration; D019999:Pharmaceutical Solutions; D013816:Thermodynamics
chemical_list: D004338:Drug Combinations; D019999:Pharmaceutical Solutions; D000667:Ampicillin; D000658:Amoxicillin