[Lipid peroxidation, the antioxidant system and the trace element level in acute pancreatitis].
Overall, thirty-two patients with acute pancreatitis (edematous, destructive, purulent forms) were studied for the state of lipid peroxidation (LPO), antioxidant defence (AOD), and trace element status. The development of destructive and purulent forms of acute pancreatitis was found out to be accompanied by activation of LPO processes, AOD breakdown, with profound disturbances having been disclosed in the metabolism of zinc, selenium, cuprum, manganum, that play an important part in LPO, AOD processes, and in those of immune defence. The secured results suggest that there is a need for us to include into a complex therapy of acute pancreatitis antioxidants and some trace elements (zinc, celenium) and that it is expedient to use indices for the LPO, AOD systems, and for trace element status in the differential diagnosis of clinical forms of acute pancreatitis, prognostication of development of purulent complications.
Kriuchyna
Ie A
IeA
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D015227:Lipid Peroxidation; D008875:Middle Aged; D010195:Pancreatitis / Q000097:blood*; D019283:Pancreatitis, Acute Necrotizing / Q000097:blood; D019512:Pancreatitis, Alcoholic / Q000097:blood; D014131:Trace Elements / Q000097:blood*
D000975:Antioxidants; D014131:Trace Elements
Stan perekysnoho okyslennia lipidiv, antyoksydantnoï systemy ta vmist mikroelementiv pry hostromu pankreatyti.