title: Homer: a link between neural activity and glutamate receptor function.
abstract: The proteins of the Homer family bind to proline-rich sequences in group I metabotropic glutamate receptors, inositol trisphosphate receptors, ryanodine receptors, and Shank family proteins. Homer proteins also self associate and function as adaptors to couple interacting proteins. Recent observations indicate a role for Homer complexes in signal transduction, synaptogenesis and receptor trafficking.
authors.affiliation: Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
authors.forename: B
authors.initials: B
authors.lastname: Xiao
authors.forename: J C
authors.initials: JC
authors.lastname: Tu
authors.forename: P F
authors.initials: PF
authors.lastname: Worley
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000502:physiology*; D000072233:Homer Scaffolding Proteins; D006801:Humans; D009474:Neurons / Q000502:physiology*; D009479:Neuropeptides / Q000502:physiology*; D017470:Receptors, Glutamate / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*
chemical_list: D002352:Carrier Proteins; D000072233:Homer Scaffolding Proteins; D009479:Neuropeptides; D017470:Receptors, Glutamate