Transcriptional profiling: is it worth the money?
Transcriptional profiling on DNA arrays has become a synonym for the type of analyses that aim to understand cellular functioning in a comprehensive manner. In this review, the status of the technology is briefly discussed, with emphasis on some inherent weaknesses and problems.
Hoheisel
J D
JD
Functional Genome Analysis, Deutsches Krebsforschungszentrum, Heidelberg, Germany. j.hoheisel@dkfz-heidelberg.de
Vingron
M
M
D020869:Gene Expression Profiling / Q000191:economics* / Q000379:methods*; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis