title: Application of the Vettest 8008 system for the biochemical analysis of vervet monkey plasma.
abstract: A clinical biochemistry analyser designed specifically for veterinary use was used to analyse plasma samples from 24 vervet monkeys (Cercopithecus aethiops). Two millilitres of heparinised blood was collected from each of the 24 monkeys on four occasions at intervals of one week. Plasma was separated and analysed for the concentrations of triglycerides, cholesterol, total proteins, albumin, globulins, creatinine and blood urea nitrogen (BUN) and the activities of alkaline phosphatase (AP), lactate dehydrogenase (LDH), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and creatine kinase (CK). The tests were easy to perform, used small volumes of plasma, and yielded consistent results for most of the analytes. The activities of CK and AP, but not AST, appeared to be influenced by haemolysis, and there were significant individual variations in the activity of LDH.
authors.affiliation: Kenya Trypanosomiasis Research Institute, Kikuyu.
authors.forename: R M
authors.initials: RM
authors.lastname: Ngure
authors.forename: L M
authors.initials: LM
authors.lastname: Gateri
authors.forename: J M
authors.initials: JM
authors.lastname: Ngotho
authors.forename: J M
authors.initials: JM
authors.lastname: Ndung'u
mesh_terms: D000818:Animals; D002522:Chlorocebus aethiops / Q000097:blood*; D004867:Equipment Design; D005260:Female; D006403:Hematologic Tests / Q000379:methods / Q000662:veterinary; D008297:Male; D012016:Reference Values; D012680:Sensitivity and Specificity; D014352:Trypanosomiasis / Q000503:physiopathology / Q000662:veterinary