Low-fat, high-carbohydrate diets and atherogenic risk.
The debate surrounding the use of low-fat, high-carbohydrate diets has raised concerns regarding the atherogenicity of triglyceride-rich lipoproteins. A recent study has demonstrated that feeding a diet high in carbohydrate delays very low-density lipoprotein (VLDL) clearance. The same diet fed to mildly hyperinsulinemic subjects delays both VLDL and chylomicron clearance without affecting triglyceride production.
Baum
C L
CL
Nutrition and Wellness Center, University of Illinois at Chicago 60612, USA.
Brown
M
M
D001161:Arteriosclerosis / Q000209:etiology* / Q000517:prevention & control; D002914:Chylomicrons / Q000097:blood; D018752:Diet, Fat-Restricted; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006946:Hyperinsulinism / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood*
D002914:Chylomicrons; D004040:Dietary Carbohydrates; D008079:Lipoproteins, VLDL; D014280:Triglycerides