CT screening for lung cancer.
Recommendations against screening for lung cancer were based on the lack of a reduction in mortality of the screened group as compared with the control group in randomized control trials. These results were interpreted as showing that early detection of lung cancer as a result of screening did not decrease the mortality rate compared with detection after presentation of symptoms for the populations being screened. Evidence, however, shows that earlier-stage intervention leads to substantially higher rates of survival. Screening, therefore, is an effective means to prevent deaths from this otherwise fatal disease. This article discusses the evidence of both CT and chest radiograph screening.
Henschke
C I
CI
Department of Radiology, New York Presbyterian Hospital, Joan and Sanford I. Weill Medical College, Cornell University, New York, USA.
Yankelevitz
D F
DF
D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000401:mortality; D015996:Survival Rate; D014057:Tomography, X-Ray Computed