title: Cytotoxic cembrenolide diterpenes from the formosan soft coral lobophytum crassum.
abstract: A new cytotoxic cembrenolide diterpene, lobocrassolide (1), and a known cytotoxic cembrenolide, lobohedleolide (2), were isolated from the Formosan soft coral Lobophytum crassum. The structure of compound 1 was determined by 1D and 2D spectral analysis.
authors.affiliation: Department of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, Republic of China.
authors.forename: C Y
authors.initials: CY
authors.lastname: Duh
authors.forename: S K
authors.initials: SK
authors.lastname: Wang
authors.forename: B T
authors.initials: BT
authors.lastname: Huang
authors.forename: C F
authors.initials: CF
authors.lastname: Dai
mesh_terms: D000818:Animals; D001643:Bridged Bicyclo Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D003063:Cnidaria / Q000737:chemistry*; D003603:Cytotoxins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D007941:Leukemia P388 / Q000378:metabolism; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: D001643:Bridged Bicyclo Compounds; D003603:Cytotoxins; D004224:Diterpenes; D005663:Furans; C412928:lobocrassolide; C409627:lobohedleolide