title: Polyoxygenated bipyridine, pyrrolylpyridine, and bipyrrole alkaloids from Speranskia tuberculata.
abstract: Five novel polyoxygenated alkaloids, speranculatines A-C (3-5), speranskilatine A (6), and speranberculatine A (7), have been isolated from Speranskia tuberculata. Compounds 3-5, 6, and 7, have bipyridine, pyrrolylpyridine, and bipyrrole skeletons, respectively. This is the first time that these three alkaloid structural types have been reported. The structures of 3-7 were elucidated by spectroscopic methods, including 2D NMR techniques and X-ray crystallographic analysis.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Bejing 100050, People's Republic of China. shijiangong@263.net
authors.forename: J G
authors.initials: JG
authors.lastname: Shi
authors.forename: H Q
authors.initials: HQ
authors.lastname: Wang
authors.forename: M
authors.initials: M
authors.lastname: Wang
authors.forename: Y C
authors.initials: YC
authors.lastname: Yang
authors.forename: W Y
authors.initials: WY
authors.lastname: Hu
authors.forename: G X
authors.initials: GX
authors.lastname: Zhou
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D019665:Euphorbiaceae / Q000737:chemistry*; D005583:Fourier Analysis; D008958:Models, Molecular; D011725:Pyridines / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014961:X-Ray Diffraction
chemical_list: D000470:Alkaloids; D011725:Pyridines; D011758:Pyrroles