Mechanisms of action of methotrexate.
Genestier
L
L
Laboratory of Immunopharmacology, Institut National de la Santé et de la Recherche Médicale U503, Claude Bernard University, Hopital E. Herriot, Pav. P, 5 Place d'Arsonval 69437, Cedex 03, Lyon, France.
Paillot
R
R
Quemeneur
L
L
Izeradjene
K
K
Revillard
J P
JP
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D008727:Methotrexate / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D011685:Purine Nucleotides / Q000096:biosynthesis*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007166:Immunosuppressive Agents; D011685:Purine Nucleotides; D008727:Methotrexate