title: Interpretation and diagnostic implications of an immunoblotting (INNOLIA) test for HCV serology.
abstract: The association analysis of antibodies versus HCV, carried out with INNOLIA test, prevented a clear determination of the existence of specific serological patterns. In this respect, it may be of interest to monitor the immune response to the non-structural genomic regions (NS3, NS4, NS5). The INNOLIA kit is reliable, but susceptible to improvement in terms of specificity, sensitivity and biological standardization.
authors.affiliation: USL 3 Genovese Clinical Pathology Department, University of Genoa.
authors.forename: G
authors.initials: G
authors.lastname: Ravera
authors.forename: M
authors.initials: M
authors.lastname: Franceschini
authors.forename: R
authors.initials: R
authors.lastname: Monacelli
authors.forename: L C
authors.initials: LC
authors.lastname: Bottaro
authors.forename: T
authors.initials: T
authors.lastname: Colombi
authors.forename: C
authors.initials: C
authors.lastname: Specchia
mesh_terms: D006526:Hepatitis C / Q000175:diagnosis*; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D015151:Immunoblotting / Q000379:methods* / Q000592:standards; D011933:Reagent Kits, Diagnostic; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric
chemical_list: D018937:Hepatitis C Antibodies; D011933:Reagent Kits, Diagnostic