Estrogen receptor deficiency leads to impaired endothelial nitric oxide production and premature coronary arteriosclerosis.
Rubanyi
G M
GM
Gene Therapy and Genomics Research, Berlex Biosciences, Richmond, California 94804, USA. gabor_rubanyi@berlex.com
D000328:Adult; D017668:Age of Onset; D000818:Animals; D003324:Coronary Artery Disease / Q000235:genetics* / Q000503:physiopathology; D004730:Endothelium, Vascular / Q000503:physiopathology*; D047628:Estrogen Receptor alpha; D006801:Humans; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D009569:Nitric Oxide / Q000378:metabolism*; D011960:Receptors, Estrogen / Q000172:deficiency / Q000235:genetics* / Q000502:physiology*
D047628:Estrogen Receptor alpha; D011960:Receptors, Estrogen; D009569:Nitric Oxide