title: Occluded infarct-related arteries and clinical events.
abstract: Late patency of the infarct-related artery has been shown to be associated with improved long-term survival rates in observational cohort studies. However, there is a dearth of randomized trials correlating the opening of persistently occluded infarct-related arteries with clinical outcomes. Recent technological advances have improved the success and safety of percutaneous revascularization, resulting in lower restenosis and reocclusion rates. A large randomized trial is needed to evaluate clinical outcomes with percutaneous revascularization versus medical management of occluded infarct-related arteries in the absence of inducible ischemia.
authors.affiliation: Cardiovascular Research Unit, Green Lane Hospital, Auckland, New Zealand.
authors.forename: M
authors.initials: M
authors.lastname: Lund
authors.forename: J K
authors.initials: JK
authors.lastname: French
authors.forename: H D
authors.initials: HD
authors.lastname: White
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D001026:Coronary Artery Bypass; D003331:Coronary Vessels / Q000187:drug effects / Q000503:physiopathology* / Q000601:surgery; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D009203:Myocardial Infarction / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy; D015425:Myocardial Reperfusion; D055502:Secondary Prevention; D015912:Thrombolytic Therapy; D013997:Time Factors
chemical_list: D005343:Fibrinolytic Agents