title: Influence of disease duration on visual evoked potentials in migraineurs.
abstract: OBJECTIVE
  To determine the possible influence of the duration of migraine on pattern-reversal visual evoked potentials.
  
  
  METHODS
  An investigation was conducted in 49 patients with migraine without aura according to the International Headache Society criteria. Twenty-two of these patients had had migraine for 2 years or less (group 1), and the other 27 patients had had the disease for 10 years or more (group 2). The control group consisted of 17 healthy subjects.
  
  
  RESULTS
  Comparison of the mean P100 latency and amplitude showed no significant difference among the groups. There was, however, a good negative correlation between age and latency (r = -0.59, P =.003) in group 1, but no such correlation was observed for group 2 or the control group.
  
  
  CONCLUSIONS
  It was concluded that the duration of migraine has no influence on pattern-reversal visual evoked potentials and that the pathogenesis of early- and late-onset migraine may be different.
authors.affiliation: Ankara University Faculty of Medicine, Department of Neurology, Turkey.
authors.forename: C
authors.initials: C
authors.lastname: Yücesan
authors.forename: O
authors.initials: O
authors.lastname: Sener
authors.forename: N
authors.initials: N
authors.lastname: Mutluer
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000704:Analysis of Variance; D002908:Chronic Disease; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020326:Migraine without Aura / Q000503:physiopathology*; D010775:Photic Stimulation; D011930:Reaction Time