title: Isolated sphenoid sinus diseases: report of 39 cases.
abstract: OBJECTIVE
  To detail the underlying pathological conditions, symptoms, signs, and outcomes of patients with isolated sphenoid sinus involvement.
  
  
  METHODS
  A retrospective survey.
  
  
  METHODS
  An academic referral center of a university hospital.
  
  
  METHODS
  All 39 patients, aged 7 to 85 years, treated in the Department of Otorhinolaryngology, Kuopio University Hospital, Kuopio, Finland, from 1988 through 1997 for isolated sphenoid sinus disease.
  
  
  RESULTS
  Sinusitis was characterized as acute in 26 patients, subacute in 5 (including 1 pyocele), and chronic in 8 (including 2 fungal infections). No tumors were found. Isolated sinus cysts were excluded from the study. Headache, the main symptom in 32 patients (82%), was localized most commonly on the vertex. Other common complaints were rhinitis, dizziness, eye symptoms, and fever. In 2 patients, the finding was occult. Eight patients (21%) presented with cranial nerve deficits, and 1 patient had an intracranial complication. Sinus irrigation was performed in 16 patients (41%) and sphenoidotomy was performed in 10 (26%). Fifteen patients (38%) were treated with antibiotic drugs alone. Within 3 months, 31 (84%) of 37 patients had recovered from the illness; 5 still experienced headaches despite having normalized radiographic findings; and 1 had permanent unilateral visual loss. Two patients were lost to follow-up.
  
  
  CONCLUSIONS
  Sphenoid sinus opacity is mostly inflammatory in origin. Despite the benign nature of the disease, there is a risk of complications with high morbidity and mortality. Early and, if necessary, aggressive therapy to guarantee drainage of the sinus is recommended.
authors.affiliation: Department of Otorhinolaryngology, Kuopio University Hospital, Finland. pirkko.ruoppi@kuh.fi
authors.forename: P
authors.initials: P
authors.lastname: Ruoppi
authors.forename: J
authors.initials: J
authors.lastname: Seppä
authors.forename: M
authors.initials: M
authors.lastname: Pukkila
authors.forename: J
authors.initials: J
authors.lastname: Nuutinen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D004322:Drainage; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010254:Paranasal Sinus Diseases / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D012189:Retrospective Studies; D013101:Sphenoid Sinus