title: [Molecular evolution more than three billion years ago].
abstract: The earlier stages of life evolution at the molecular level were reconstructed. A set of triplets incorporated into the earliest RNA molecules (mRNA) was determined. It is believed that tRNA is one of the descedants of the earliest protein-encoding sequences. It was shown that tRNA has a hidden periodic structure of base sequences that conforms to the rule (GNY)n, indicating it ancient age. A set of the earliest amino acids was established and their distribution with respect to age was made. It was shown that genomes were built from elementary units (primary genes) by recombination or binding some time prior to division into eukaryotes and prokaryotes. Mean dimensions of the elementary unit for eukaryotes and prokaryotes were determined.
authors.affiliation: Department of Structural Biology, Weizmann Institute of Sciences, Rechovot, Israel.
authors.forename: E N
authors.initials: EN
authors.lastname: Trifonov
mesh_terms: D000818:Animals; D019143:Evolution, Molecular; D005796:Genes; D016678:Genome; D011995:Recombination, Genetic
vernacular_title: Moleculiarnaia évoliutsiia svyshe trekh milliardov let nazad.