title: Biological basis for clinical success: pulp protection and the tooth-restoration interface.
abstract: This article provides biological and technological information that strengthens clinicians' understanding of cohesive hybridization and pulp therapy in order to support their routine use of bonding and resin systems. Utilizing cohesive systems, clinicians should experience several advantages over traditional water-soluble base and liner systems. When properly applied, cohesive hybridization of vital dentin prevents immediate postoperative hypersensitivity under all restorations and completely seals the entire tooth-restoration interface, which provides a reduction in recurrent caries.
authors.affiliation: Department of Biomaterials, University of Alabama School of Dentistry, Birmingham 35294-0007, USA.
authors.forename: C F
authors.initials: CF
authors.lastname: Cox
authors.forename: A A
authors.initials: AA
authors.lastname: Hafez
authors.forename: N
authors.initials: N
authors.lastname: Akimoto
authors.forename: M
authors.initials: M
authors.lastname: Otsuki
authors.forename: J C
authors.initials: JC
authors.lastname: Mills
mesh_terms: D000818:Animals; D002126:Calcium Hydroxide; D001840:Dental Bonding; D003736:Dental Cavity Lining; D003763:Dental Leakage / Q000150:complications / Q000517:prevention & control*; D003785:Dental Pulp Capping; D003789:Dental Pulp Exposure / Q000209:etiology / Q000517:prevention & control*; D003793:Dental Restoration, Permanent / Q000379:methods*; D003807:Dentin Sensitivity / Q000517:prevention & control; D003809:Dentin, Secondary / Q000254:growth & development; D017220:Dentin-Bonding Agents; D006801:Humans; D019279:Resin Cements
chemical_list: D017220:Dentin-Bonding Agents; D019279:Resin Cements; D002126:Calcium Hydroxide