title: Conversion of quassinoids for enhancement of inhibitory effect against Epstein-Barr virus early antigen activation. Introduction of lipophilic side chain and esterification of diosphenol.
abstract: Introduction of a senecioyl group into shinjulactones B and C, and esterification of the diosphenol moiety in brusatol and brucein A enhanced inhibitory effect against Epstein-Barr virus early antigen activation.
authors.affiliation: Department of Interdisciplinary Studies of Natural Environment, Faculty of Integrated Arts and Sciences, Hiroshima University, Higashi-Hiroshima, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Tamura
authors.forename: N
authors.initials: N
authors.lastname: Fukamiya
authors.forename: X Y
authors.initials: XY
authors.lastname: Mou
authors.forename: T
authors.initials: T
authors.lastname: Mukainaka
authors.forename: H
authors.initials: H
authors.lastname: Tokuda
authors.forename: H
authors.initials: H
authors.lastname: Nishino
authors.forename: K
authors.initials: K
authors.lastname: Tagahara
authors.forename: K
authors.initials: K
authors.lastname: Koike
authors.forename: K H
authors.initials: KH
authors.lastname: Lee
authors.forename: M
authors.initials: M
authors.lastname: Okano
mesh_terms: D000956:Antigens, Viral / Q000187:drug effects*; D004951:Esterification; D005419:Flavonoids / Q000737:chemistry* / Q000494:pharmacology*; D010636:Phenols / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D000956:Antigens, Viral; C033305:Epstein-Barr virus early antigen; D005419:Flavonoids; D010636:Phenols