title: [Chronic hepatitis C in HIV-infected patients. Unfavorable interaction of HIV and HCV infection].
abstract: HIV coinfection promotes the progression of chronic hepatitis C. The increased hepatic mortality and improved life expectancy of HIV-positive patients warrants treatment of chronic hepatitis C in those infected with HIV. The treatment of hepatitis C considered standard for HIV-negative and, in principle, also for HIV-positive patients is the combination of interferon alpha with ribavirin. Possible interaction with the antiretroviral treatment by ribavirin must, however, taken into account. Although new therapeutic approaches are available, they have not yet been adequately validated terms of their efficacy and safety.
authors.forename: S
authors.initials: S
authors.lastname: Mauss
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy* / Q000401:mortality; D019380:Anti-HIV Agents / Q000008:administration & dosage* / Q000009:adverse effects; D000998:Antiviral Agents / Q000008:administration & dosage* / Q000009:adverse effects; D004359:Drug Therapy, Combination; D015658:HIV Infections / Q000188:drug therapy* / Q000401:mortality; D019698:Hepatitis C, Chronic / Q000188:drug therapy* / Q000401:mortality; D006801:Humans; D011379:Prognosis; D015996:Survival Rate
chemical_list: D019380:Anti-HIV Agents; D000998:Antiviral Agents
vernacular_title: Die chronische Hepatitis C bei HIV-infizierten Patienten. Ungünstige Interaktion von HIV- und HCV-Infektion.