Normal EOG values in intraretinal metastasis from cutaneous melanoma: a case report.
OBJECTIVE
The electro-oculogram (EOG) is a powerful test to diagnose primary and metastatic choroidal tumors. While in benign tumors light-peak to dark-trough ratio values are in the range of normal subjects, these values appear highly altered in eyes affected by malignant choroidal tumors. Here we report a clinical case of a patient with intraretinal metastasis from cutaneous melanoma; notwithstanding the malignancy of the tumor, the EOG doesn't present alterations.


RESULTS
Standard electro-oculographic recordings were performed before and after local excision of the tumor: recordings from the normal eye were taken as control. The EOG values were always normal in both eyes. Histological sections showed no evident change in the cell population of the retinal pigment epithelium (RPE) and Bruch's membrane.


CONCLUSIONS
Our results suggest that the presence of an intact RPE is a crucial requirement to obtain a normal EOG.
Spadea
L
L
L'Aquila University Eye Clinic, Italy. lspadea@ntt.it
Bisti
S
S
Colucci
S
S
Balestrazzi
E
E
D000328:Adult; D016570:Bruch Membrane / Q000502:physiology; D004585:Electrooculography; D005260:Female; D006801:Humans; D008545:Melanoma / Q000503:physiopathology / Q000556:secondary*; D010857:Pigment Epithelium of Eye / Q000502:physiology; D019572:Retinal Neoplasms / Q000503:physiopathology / Q000556:secondary*; D012878:Skin Neoplasms / Q000473:pathology*