Effects of prostaglandin F2alpha treatment on the behavior of pseudopregnant pigs in an extensive environment.
In seminatural environments, prepartum sows leave the herd and construct a maternal nest (a dug out hollow lined with vegetation) prior to the birth of their piglets. The endocrine drives motivating this behavior are not understood, but may involve prostaglandin (PG) F2alpha. This study examined the effect of PGF2alpha treatment on the behavior of pseudopregnant gifts housed in a large enclosure. Pseudopregnancy was induced using 5 mg/ml estradiol valerate/day im from days 11 to 15 of the estrous cycle (first day of estrus = day 0). The gifts' behavior was recorded on a control day, during which no treatment was given, and a test day (= 45.9 +/- 0.42 days of pseudopregnancy) when gilts received either 15 mg PGF2alpha (dinoprost: Lutalyse, Upjohn, Crawley, UK, n = 11) or 0.9% saline (n = 10) im at 11.00 h. PGF2alpha-treated gilts traveled further and were more frequently >10 m from the nearest pig than saline-treated animals. In the hour following injection, PGF2alpha-treated animals also showed increased frequencies of rooting and pawing the ground and stood for longer than saline-treated animals. However, gathering and carrying nest materials were not increased. These results suggest that PGF2alpha, given as a single dose to extensively housed gilts, initiated many, but not all, of the behaviors characteristic of prepartum nest building. The dose and duration of PGF2alpha treatment may have limited the observed behaviors. In addition, environmental feedback is likely to affect the degree to which some nest building behaviors are expressed.
Gilbert
C L
CL
Department of Neurobiology, The Babraham Institute, Cambridge, United Kingdom.
Murfitt
P J
PJ
Boulton
M I
MI
Pain
J
J
Burne
T H
TH
D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology; D015237:Dinoprost / Q000494:pharmacology*; D004777:Environment; D005260:Female; D008124:Locomotion / Q000187:drug effects / Q000502:physiology; D009425:Nesting Behavior / Q000187:drug effects* / Q000502:physiology; D010120:Oxytocics / Q000494:pharmacology*; D011555:Pseudopregnancy / Q000503:physiopathology*; D012934:Social Isolation; D013552:Swine
D010120:Oxytocics; D015237:Dinoprost