Intracellular cholesterol trafficking: role of the NPC1 protein.
Blanchette-Mackie
E J
EJ
Laboratory of Cell Biochemistry and Biology, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 30892-0850, USA. joanbm@bdg8.niddk.nih.gov
D000736:Androstenes / Q000494:pharmacology; D000818:Animals; D001692:Biological Transport; D016466:CHO Cells; D002352:Carrier Proteins; D002462:Cell Membrane / Q000378:metabolism*; D002784:Cholesterol / Q000096:biosynthesis / Q000378:metabolism*; D008078:Cholesterol, LDL / Q000378:metabolism; D006224:Cricetinae; D004705:Endocytosis; D004721:Endoplasmic Reticulum / Q000378:metabolism; D005347:Fibroblasts; D006056:Golgi Apparatus / Q000187:drug effects / Q000378:metabolism; D006706:Homeostasis; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D008562:Membrane Glycoproteins; D009154:Mutation; D000077296:Niemann-Pick C1 Protein; D011506:Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D014162:Transfection
D000736:Androstenes; D002352:Carrier Proteins; D008078:Cholesterol, LDL; D047908:Intracellular Signaling Peptides and Proteins; D008562:Membrane Glycoproteins; C106881:NPC1 protein, human; D000077296:Niemann-Pick C1 Protein; D011506:Proteins; C006261:3-beta-(2-(diethylamino)ethoxy)androst-5-en-17-one; D002784:Cholesterol