title: Management of infections in patients with acute leukemia.
abstract: Several recent studies have addressed the management of infectious problems in patients with acute leukemia. Although those studies have served to emphasize the fundamental management principles formulated and proven almost 30 years ago, they have also contributed important new insights. This article describes recent developments in the management of infectious illnesses in patients who are neutropenic due to leukemia or its treatment. The discussion will focus on the increasing armamentarium of antimicrobial drugs and adjunctive agents. These expanding therapeutic options must be viewed in the context of newly emerging resistant organisms and special problems, such as the increased use of indwelling venous catheters.
authors.affiliation: University of Maryland School of Medicine, Baltimore, USA.
authors.forename: C B
authors.initials: CB
authors.lastname: Sarkodee-Adoo
authors.forename: W G
authors.initials: WG
authors.lastname: Merz
authors.forename: J E
authors.initials: JE
authors.lastname: Karp
mesh_terms: D000208:Acute Disease; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001424:Bacterial Infections / Q000188:drug therapy / Q000517:prevention & control; D006801:Humans; D007938:Leukemia / Q000188:drug therapy*; D009181:Mycoses / Q000188:drug therapy / Q000517:prevention & control; D009503:Neutropenia / Q000139:chemically induced / Q000150:complications*; D009894:Opportunistic Infections / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000890:Anti-Infective Agents; D000935:Antifungal Agents; D000970:Antineoplastic Agents