Successful treatment of relapsed Burkitt's lymphoma using unrelated cord blood transplantation as consolidation therapy.
We report a 10-year-old male with widespread recurrent Burkitt's lymphoma who underwent successful mismatched unrelated cord blood transplantation (UCBT) following salvage chemotherapy. He was conditioned with TBI, antithymocyte globulin (ATG) and high-dose VP-16 and achieved full donor engraftment. He experienced grade II skin and grade I gastrointestinal acute GVHD with no chronic GVHD. He is alive with no evidence of disease 24 months following UCBT. Bone Marrow Transplantation (2000) 25, 1311-1313.
Weinthal
J A
JA
Texas Oncology Pediatrics and North Texas Hospital for Children at Medical City Dallas Hospital, Dallas, TX, USA.
Goldman
S C
SC
Lenarsky
C
C
D002051:Burkitt Lymphoma / Q000473:pathology / Q000628:therapy*; D002648:Child; D005312:Fetal Blood; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008297:Male; D012008:Recurrence; D014184:Transplantation, Homologous