title: Intravenous detergent poisoning.
abstract: In the literature regarding surfactant poisoning, the route of exposure has almost always been oral. We report a case in which about 40 mL of bath detergent for home use was self-injected. The primary pathophysiologic effects were relative hypovolemia and cardiac dysfunction. The patient experienced frequent ventricular tachycardia, acute renal failure, rhabdomyolysis, hemolysis, and coagulation dysfunction. Intensive care included the administration of antiarrythmial agents and hemodialysis. The patient survived and was discharged from our hospital without sequelae.
authors.affiliation: Department of Acute Medicine, Kawasaki Medical School Hospital, Kurashiki-city, Okayama, Japan. xj2t-okmr@asahi-net.or.jp
authors.forename: T
authors.initials: T
authors.lastname: Okumura
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: K
authors.initials: K
authors.lastname: Yamane
authors.forename: K
authors.initials: K
authors.lastname: Kumada
authors.forename: R
authors.initials: R
authors.lastname: Kobayashi
authors.forename: A
authors.initials: A
authors.lastname: Fukuda
authors.forename: C
authors.initials: C
authors.lastname: Fujii
authors.forename: A
authors.initials: A
authors.lastname: Kohama
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced / Q000628:therapy; D000328:Adult; D000889:Anti-Arrhythmia Agents; D001778:Blood Coagulation Disorders / Q000139:chemically induced / Q000628:therapy; D003902:Detergents / Q000506:poisoning*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D020896:Hypovolemia / Q000139:chemically induced / Q000628:therapy; D007275:Injections, Intravenous; D008297:Male; D011041:Poisoning / Q000628:therapy; D006435:Renal Dialysis; D012206:Rhabdomyolysis / Q000139:chemically induced / Q000628:therapy; D013406:Suicide, Attempted; D017180:Tachycardia, Ventricular / Q000139:chemically induced / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000889:Anti-Arrhythmia Agents; D003902:Detergents