title: Increase in O(2) delivery with hyperoxia does not increase O(2) uptake in tetanically contracting dog muscle.
abstract: We investigated the influence of hyperoxia on O(2) uptake in tetanically contracting canine gastrocnemius. Hyperoxia showed neither increase in O(2) uptake nor decrease in lactate release, irrespective of increased O(2) supply, venous Po(2) and vascular resistance, as compared to normoxia, suggesting that hyperoxia decreases O(2) diffusion conductance and/or effective O(2) supply probably due to arteriovenous O(2) diffusion shunt.
authors.affiliation: Department of Physiology II, Nara Medical University, Kashihara, 634-8521 Japan. hkohzuki@naramed-u.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Kohzuki
authors.forename: S
authors.initials: S
authors.lastname: Sakata
authors.forename: Y
authors.initials: Y
authors.lastname: Ohga
authors.forename: H
authors.initials: H
authors.lastname: Misawa
authors.forename: T
authors.initials: T
authors.lastname: Kishi
authors.forename: M
authors.initials: M
authors.lastname: Takaki
mesh_terms: D015308:Anaerobic Threshold / Q000502:physiology; D000818:Animals; D001160:Arterioles / Q000502:physiology; D004058:Diffusion; D004285:Dogs; D004912:Erythrocytes / Q000378:metabolism; D018496:Hyperoxia / Q000503:physiopathology*; D007773:Lactates / Q000378:metabolism; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000098:blood supply / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism; D010101:Oxygen Consumption / Q000502:physiology*; D014655:Vascular Resistance / Q000502:physiology
chemical_list: D007773:Lactates; D010100:Oxygen