title: Evolution of parasite virulence against qualitative or quantitative host resistance.
abstract: We analysed the effects of two different modes of host resistance on the evolution of parasite virulence. Hosts can either adopt an all-or-nothing qualitative response (i.e. resistant hosts cannot be infected) or a quantitative form of resistance (i.e. which reduces the within-host growth rate of the parasite). We show that the mode of host resistance greatly affects the evolutionary outcome. Specifically, a qualitative form of resistance reduces parasite virulence, while a quantitative form of resistance generally selects for higher virulence.
authors.affiliation: Laboratoire d'Ecologie, CNRS-UMR 7625 Case 237, Université Pierre et Marie Curie, Paris, France. sgandon@snv.jussieu.fr
authors.forename: S
authors.initials: S
authors.lastname: Gandon
authors.forename: Y
authors.initials: Y
authors.lastname: Michalakis
mesh_terms: D000818:Animals; D005075:Biological Evolution; D006790:Host-Parasite Interactions; D008954:Models, Biological; D010271:Parasites / Q000276:immunology / Q000472:pathogenicity*; D014774:Virulence