title: Association of tuberculosis with malignancy at KIMIO--an oncology centre.
abstract: The association of tuberculosis and malignancy was studied at an oncology centre in Bangalore. The study period was from January 1981 to December 1995. A total of 8779 clinical material obtained from patients were screened for Mycobacterium tuberculosis infection. Out of which 675 were positive for acidfast bacilli, 385 from non malignant conditions and 290 from malignant conditions. Highest incidence is seen in Head and Neck cancer (42%) followed by Gastrointestinal cancer (14.1%), Lung cancer (13.8%), Haematological cancer (10.7%), Reproductive cancer (10.3%) and miscellaneous group (9%), Antibiogram of Mycobacterial cultures was done in 282 subjects. Resistance patterns to antitubercular drugs showed highest with Isonicotinic acid hydrochloride (INH) (17.7%), followed by para amino salicylic acid (PAS) (8.5%), Streptomycin (SM) (6.7%), Rifampicin (RIF) (4.6%) and Ethambutol (EM) (0.35%).
authors.affiliation: Department of Microbiology, Kidwai Memorial Institute of Oncology, Bangalore.
authors.forename: R R
authors.initials: RR
authors.lastname: Kumar
authors.forename: M
authors.initials: M
authors.lastname: Shafiulla
authors.forename: H
authors.initials: H
authors.lastname: Sridhar
mesh_terms: D002173:Cancer Care Facilities; D006801:Humans; D007194:India / Q000453:epidemiology; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D009369:Neoplasms / Q000150:complications*; D012189:Retrospective Studies; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000453:epidemiology