A supportive-expressive group intervention for women with a family history of breast cancer: results of a phase II study.
BACKGROUND
Evidence suggests that there are significant psychological and behavioural sequelae associated with having a family history of breast cancer (BC) which can interfere with comprehension of risk estimates.


OBJECTIVE
The purpose of this study was to develop, standardize and do preliminary testing of a group intervention designed to address the emotional impact of having a family history of BC.


METHODS
This study is a single-arm pilot design with pre- and post-measures of perceived risk, psychosocial distress, knowledge and screening practices.


RESULTS
The primary study outcome measure of risk comprehension was significantly improved by 70%, according to our predetermined criteria for success. In addition, the most important secondary measures of psychosocial functioning, such as cancer-related distress (p=0.025), depression (p=0.05), anxiety (p=0.005) and unresolved grief (p=0.034) were significantly improved.


CONCLUSIONS
The results of this initial pilot study are encouraging; however, further research is required, using a randomized controlled study design to evaluate the relative contribution of this intervention to the successful modification of risk comprehension, enhanced psychological functioning, and to promote optimal screening adherence.
Esplen
M J
MJ
Department of Psychiatry, Mount Sinai Hospital, Toronto, Ontario, Canada. mesplen@mtsinai.on.ca
Toner
B
B
Hunter
J
J
Glendon
G
G
Liede
A
A
Narod
S
S
Stuckless
N
N
Butler
K
K
Field
B
B
D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D000339:Affect; D000368:Aged; D001294:Attitude to Health; D001943:Breast Neoplasms / Q000235:genetics*; D003863:Depression / Q000628:therapy; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D008875:Middle Aged; D010865:Pilot Projects; D012307:Risk Factors; D012917:Social Adjustment; D013315:Stress, Psychological / Q000628:therapy*; D011795:Surveys and Questionnaires