title: Analysis of gene expression profile during 3T3-L1 preadipocyte differentiation.
abstract: Cellular differentiation is a process in which a group of differentiation specific genes is programmatically induced. This gene expression program leads to changes in both cellular morphological and physiological phenotypes. Using an 18,376-member cDNA/EST microarray, we analyzed the difference in gene expression profiles between differentiated 3T3-L1 adipocyte and non-differentiated 3T3-L1 preadipocyte. From our study a large number of genes and ESTs were identified as differentially induced or suppressed. In this paper we describe the changes of gene expression profile during 3T3-L1 cell differentiation.
authors.affiliation: Shanghai Life Sciences Research Center, Chinese Academy of Sciences, People's Republic of China.
authors.forename: X
authors.initials: X
authors.lastname: Guo
authors.forename: K
authors.initials: K
authors.lastname: Liao
mesh_terms: D016475:3T3 Cells; D017667:Adipocytes / Q000166:cytology / Q000378:metabolism*; D000818:Animals; D002454:Cell Differentiation / Q000235:genetics*; D018076:DNA, Complementary; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D051379:Mice; D009693:Nucleic Acid Hybridization; D020411:Oligonucleotide Array Sequence Analysis; D012333:RNA, Messenger / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D018076:DNA, Complementary; D012333:RNA, Messenger