title: [Acute renal failure after polyvalent immunoglobulin therapy].
abstract: BACKGROUND
  Acute renal failure can be induced by intravenous administration of immunoglobulins, especially in patients with a predisposition for nephrotoxicity. The onset and resolution of acute renal failure is typically rapid, but in some cases hemodialysis may be needed.
  
  
  METHODS
  We present 2 cases of acute renal failure associated with intravenous immunoglobulin therapy: a 76-year-old man with a history of non-insulin-dependent diabetes mellitus and hypertension and a 77-year-old woman using nonsteroidal antiinflammatory drugs.
  
  
  CONCLUSIONS
  Intravenous immunoglobulins must be used with precaution in patients with risk factors for acute renal failure. In such patients, renal failure may be avoided by using preparations without sucrose.
authors.affiliation: Service de Néphrologie et d'Hémodialyse, CHU Pellegrin, Bordeaux.
authors.forename: M S
authors.initials: MS
authors.lastname: Dilhuydy
authors.forename: C
authors.initials: C
authors.lastname: Delclaux
authors.forename: V
authors.initials: V
authors.lastname: De Precigout
authors.forename: F
authors.initials: F
authors.lastname: Haramburu
authors.forename: I
authors.initials: I
authors.lastname: Roger
authors.forename: C
authors.initials: C
authors.lastname: Deminière
authors.forename: P
authors.initials: P
authors.lastname: Mercié
authors.forename: J L
authors.initials: JL
authors.lastname: Pellegrin
authors.forename: M
authors.initials: M
authors.lastname: Aparicio
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000175:diagnosis; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000175:diagnosis; D003928:Diabetic Nephropathies / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D007116:Immunization, Passive / Q000009:adverse effects*; D007677:Kidney Function Tests; D008297:Male; D009220:Myositis / Q000188:drug therapy*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000188:drug therapy*; D012307:Risk Factors
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal
vernacular_title: Inuffisance rénale aiguë après cure d'immunoglobulines polyvalentes.