title: Doppler flow patterns through the ductus arteriosus in patients with congenital diaphragmatic hernia.
abstract: We investigated Doppler flow patterns through the ductus arteriosus (DA) of 13 newborn infants with congenital diaphragmatic hernia (CDH) using color Doppler ultrasonography (CDUS). Patterns were classified into 3 types: left-to-right (L-R), bidirectional (BD) and right-to-left (R-L) shunting. Among the 13 patients examined, 3 showed L-R shunting, 5 BD shunting and 5 R-L shunting. Patients with L-R shunting showed significantly better levels of PaO2 and AaDO2 than those with other Doppler flow patterns. However, there were no differences in clinical findings between patients with BD and R-L shunting. All patients with L-R shunting survived after CDH repair without pre-operative stabilization including Lipo-PGE1 (LPE) administration. Four of the 5 patients with BD shunting survived, but only one of the 5 patients with R-L shunting survived after CDH repair following administration of LPE. It was suggested that Doppler flow patterns through the DA may be useful for predicting prognoses and selecting suitable treatment for CDH.
authors.affiliation: Department of Pediatric Surgery, Chiba University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tanabe
authors.forename: H
authors.initials: H
authors.lastname: Yoshida
authors.forename: J
authors.initials: J
authors.lastname: Iwai
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
authors.forename: N
authors.initials: N
authors.lastname: Ohnuma
authors.forename: M
authors.initials: M
authors.lastname: Terai
mesh_terms: D004373:Ductus Arteriosus; D006548:Hernia, Diaphragmatic / Q000000981:diagnostic imaging / Q000503:physiopathology*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D011652:Pulmonary Circulation; D018608:Ultrasonography, Doppler