title: Prostate cancer in Taiwan: epidemiology and risk factors.
abstract: The incidence of prostate cancer (PC) has been rapidly increasing in the past 10 years in Taiwan. It became the sixth common cancer in males in 1996 and resulted in 540 deaths in 1998. It was estimated that the incidence of PC would be up to 14 per 105 in the year 2000, 3-fold higher than that in 1990. Three factors may be responsible for the increase of PC in Taiwan: use of prostate specific antigen, population aging and high fat diet. A case-control study on the risk factors of PC in a patient population comprised mainly of veterans (63%) in Taiwan showed that PC patients tended to have engaged in more physical activity (adjusted odds ratio (OR): 2.16), have a lower body mass index (OR 2.0) and be less likely to consume vegetables cooked with pork lard (OR 0.47). About half of our patients had locally advanced or metastatic diseases upon diagnosis. This staging distribution was consistent in most major institutions in Taiwan and was fairly unchanged over time in the past two decades. The incidence of latent PC in Taiwan was not investigated until a pathological review of 49 cystoprostatectomy specimens recently revealed unsuspected PC in 32.7% and high-grade prostate intra epithelial neoplasia in 49% of the prostates removed. As the incidence of PC grows rapidly in Taiwan, this disease warrants more attention from the public and the authorities. More efforts should also be directed to the investigation on the risk factors for PC in the new millennium.
authors.affiliation: Department of Urology, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei, Taiwan 100, Republic of China. yspu@ha.mc.ntu.edu.tw
authors.forename: Y S
authors.initials: YS
authors.lastname: Pu
mesh_terms: D000368:Aged; D006801:Humans; D015994:Incidence; D008297:Male; D015995:Prevalence; D011471:Prostatic Neoplasms / Q000235:genetics* / Q000401:mortality / Q000469:parasitology; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology