title: Evaluation of the antiviral activity of kaempferol and its glycosides against human cytomegalovirus.
abstract: The antiviral activity of seven flavonoids, belonging to the kaempferol series, was evaluated against human cytomegalovirus (HCMV) by a rapid method of detection of the immediate-early (IE) antigen, induced by the virus in infected cells. Flavonoids bearing acyl substituents were found to be the most active compounds.
authors.forename: D
authors.initials: D
authors.lastname: Mitrocotsa
authors.forename: S
authors.initials: S
authors.lastname: Mitaku
authors.forename: S
authors.initials: S
authors.lastname: Axarlis
authors.forename: C
authors.initials: C
authors.lastname: Harvala
authors.forename: M
authors.initials: M
authors.lastname: Malamas
mesh_terms: D000998:Antiviral Agents / Q000494:pharmacology*; D003587:Cytomegalovirus / Q000187:drug effects*; D005069:Evaluation Studies as Topic; D005419:Flavonoids; D006027:Glycosides / Q000494:pharmacology*; D006801:Humans; D044949:Kaempferols; D011794:Quercetin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000998:Antiviral Agents; D005419:Flavonoids; D006027:Glycosides; D044949:Kaempferols; C006552:kaempferol; D011794:Quercetin