title: A two-dimensional fluid-structure interaction model of the aortic valve [correction of value].
abstract: Failure of synthetic heart valves is usually caused by tearing and calcification of the leaflets. Leaflet fiber-reinforcement increases the durability of these valves by unloading the delicate parts of the leaflets, maintaining their physiological functioning. The interaction of the valve with the surrounding fluid is essential when analyzing its functioning. However, the large differences in material properties of fluid and structure and the finite motion of the leaflets complicate blood-valve interaction modeling. This has, so far, obstructed numerical analyses of valves operating under physiological conditions. A two-dimensional fluid-structure interaction model is presented, which allows the Reynolds number to be within the physiological range, using a fictitious domain method based on Lagrange multipliers to couple the two phases. The extension to the three-dimensional case is straightforward. The model has been validated experimentally using laser Doppler anemometry for measuring the fluid flow and digitized high-speed video recordings to visualize the leaflet motion in corresponding geometries. Results show that both the fluid and leaflet behaviour are well predicted for different leaflet thicknesses.
authors.affiliation: Department of Mechanical Engineering, Eindhoven University of Technology, The Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: De Hart
authors.forename: G W
authors.initials: GW
authors.lastname: Peters
authors.forename: P J
authors.initials: PJ
authors.lastname: Schreurs
authors.forename: F P
authors.initials: FP
authors.lastname: Baaijens
mesh_terms: D001021:Aortic Valve / Q000033:anatomy & histology* / Q000502:physiology*; D020342:Finite Element Analysis; D006801:Humans; D008955:Models, Cardiovascular