title: Diagnostic procedures for detection of lymph node metastases in cancer of the larynx.
abstract: Squamous cell carcinoma is the most common malignant neoplasm of the larynx. One of the most important influences on prognosis is the presence of metastases to the cervical lymph nodes. Accurate determination of lymph node involvement is therefore a prerequisite for individualized therapy in patients with squamous cell carcinoma of the larynx. Clinical palpation of the neck is not very accurate and the role of imaging techniques such as ultrasound, ultrasound-guided fine needle aspiration cytology, color Doppler ultrasound, computed tomography, magnetic resonance imaging and positron emission tomography is being applied in order to improve upon the results of clinical investigation alone. According to our investigations and review of the literature, the accuracy of computed tomography scanning (84.9%) and magnetic resonance imaging (85%) was superior to palpation (69.7%) and ultrasound (72.7%). Ultrasound-guided fine needle aspiration cytology showed an accuracy of 89% and was in the same range with positron emission tomography (90.5%).
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Klinikum Krefeld, Munich, Germany.
authors.forename: R J
authors.initials: RJ
authors.lastname: Kau
authors.forename: C
authors.initials: C
authors.lastname: Alexiou
authors.forename: H
authors.initials: H
authors.lastname: Stimmer
authors.forename: W
authors.initials: W
authors.lastname: Arnold
mesh_terms: D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000556:secondary*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology; D008207:Lymphatic Metastasis / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D009333:Neck; D016609:Neoplasms, Second Primary; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed; D018615:Ultrasonography, Doppler, Color