title: Meningococcal septicaemia and plastic surgery--a strategy for management.
abstract: Meningococcal septicaemia is a severe life threatening illness that is part of the spectrum of meningococcal disease. It is of particular concern to the plastic and reconstructive surgeon because as the medical and intensive care of these patients improves, more are surviving the acute phase of the septicaemia and suffering from the associated complications such as skin necrosis and extremity loss. Recently there have been several reports in the literature concerning the management of skin infarction with both skin grafting and free flap surgery. This paper will provide an update on the proposed pathophysiological mechanisms involved, summarise the present data on plastic surgical care and suggest a stratagem for future management of these difficult cases.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Addenbrooke's Hospital, Cambridge, UK.
authors.forename: T S
authors.initials: TS
authors.lastname: Potokar
authors.forename: D W
authors.initials: DW
authors.lastname: Oliver
authors.forename: R
authors.initials: R
authors.lastname: Ross Russell
authors.forename: P N
authors.initials: PN
authors.lastname: Hall
mesh_terms: D000293:Adolescent; D000328:Adult; D000465:Algorithms; D016470:Bacteremia / Q000150:complications* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D062109:Dermatologic Surgical Procedures; D005121:Extremities / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008589:Meningococcal Infections / Q000150:complications* / Q000503:physiopathology; D009336:Necrosis; D019651:Plastic Surgery Procedures / Q000379:methods*; D012867:Skin / Q000473:pathology*