title: Perfusion method for thoracoabdominal aneurysm repair using the open distal technique.
abstract: Challenges related to perfusion support of thoracoabdominal aneurysm repair include maintenance of distal aortic perfusion, rapidity of fluid resuscitation, and avoidance of both hypothermia and excessive hemodilution. Using available technology, we have devised a circuit and protocol that addresses these issues. To accomplish such support a bypass circuit consisting of 3/8 inch tubing connected to a centrifugal pump and low-prime heat exchanger was constructed. The circuit was primed via 1/4 inch spiked connectors attached to a 3-liter bag of normal saline. After initial de-airing, the solution was recirculated through this bag. Patients were anticoagulated with 1 mg/kg of heparin prior to initiation of support. Left atrial-descending aorta bypass was used primarily. A cell salvage device was used for autotransfusion. All blood products were delivered via a rapid infusion device. During partial exsanguination, shed blood was not processed, but directed to the rapid infusor for immediate retransfusion. Any packed cells given were washed prior to transfusion. Citrate dextrose solution was used as an anticoagulant for the cell scavenger. This configuration was used successfully in 50 procedures during an 18-month period. Use of this low-prime, custom circuit reduced both hemodilution and cost. A connection off the cell salvage pump offers fast retransfusion of shed blood during partial exsanguination. Minimal heparinization and citrate anticoagulation appears to reduce coagulopathy.
authors.affiliation: Perfusion Services, New York Presbyterian Hospital, Cornell Medical Center, NY 10021, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: DeBois
authors.forename: L N
authors.initials: LN
authors.lastname: Girardi
authors.forename: S
authors.initials: S
authors.lastname: Lawrence
authors.forename: J
authors.initials: J
authors.lastname: McVey
authors.forename: A
authors.initials: A
authors.lastname: Cahill
authors.forename: B
authors.initials: B
authors.lastname: Elmer
authors.forename: M
authors.initials: M
authors.lastname: Zanichelli
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical / Q000379:methods* / Q000401:mortality / Q000592:standards; D001014:Aortic Aneurysm / Q000150:complications / Q000601:surgery*; D017544:Aortic Aneurysm, Abdominal / Q000150:complications / Q000601:surgery; D017545:Aortic Aneurysm, Thoracic / Q000150:complications / Q000601:surgery; D001804:Blood Transfusion, Autologous / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010477:Perfusion / Q000379:methods*; D012189:Retrospective Studies; D015996:Survival Rate; D019616:Thoracic Surgical Procedures / Q000379:methods / Q000401:mortality / Q000592:standards