Protein arrays for gene expression and molecular interaction screening.
The array format has revolutionised biomedical experimentation and diagnostics, enabling ordered high-throughput analysis. During the past decade, classic solid phase substrates, such as microtitre plates, membrane filters and microscopic slides, were turned into high-density, chip-like structures. The concept of the arrayed library was central to this development which now extends from DNA to protein. The new and versatile protein array technology allows high-throughput screening for gene expression and molecular interactions. As a major platform for functional genomics, it is already on its way into medical diagnostics.
Walter
G
G
Biorchard AS, Oslo, N-0281, Norway. gerald@biorchard.com
Büssow
K
K
Cahill
D
D
Lueking
A
A
Lehrach
H
H
D001426:Bacterial Proteins / Q000235:genetics*; D003001:Cloning, Molecular / Q000379:methods*; D015964:Gene Expression Regulation, Bacterial; D005820:Genetic Testing / Q000379:methods*; D008828:Microbiological Techniques; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*
D001426:Bacterial Proteins