Heritability of canine hip-dysplasia score and its components in Gordon setters.
Hip dysplasia (malformation of the hip joint) is an important health problem in dogs. The condition and the control scheme for Gordon Setters was organised by the British Veterinary Association (BVA) and the Kennel Club before 1976 and use hip scores. Our analyses of hip dysplasia in Gordon Setters used both hip scores and the scores for the nine components (which collectively defined the hip score). The scores for all nine components were available for 732 females and 420 males. These clinical data were merged with the Kennel Club pedigree database (animal's identity, date of birth, and also similar data for its parents, including hip scores if the parent had been tested). Regression models showed strong positive relationships between offspring and parental hip scores as well as for some component scores. The heritability of hip dysplasia (assessed using both hip scores and the major components) was significant, particularly from dams. Our research emphasizes the need for both sires and dams--particularly dams, to have zero or small hip scores. Tested parents have been used increasingly in recent years, but greater reduction in offspring hip score will require stricter selection of potential breeding stock. The models reported here provide quantitative predictions of likely health benefits from selective breeding.
Wood
J L
JL
Animal Health Trust, Lanwades Park, Kentford, Suffolk, CB8 7UU, Newmarket, UK. james.wood@aht.org.uk
Lakhani
K H
KH
Dennis
R
R
D000822:Animal Husbandry; D000818:Animals; D004285:Dogs; D005260:Female; D006619:Hip Dysplasia, Canine / Q000235:genetics* / Q000473:pathology; D008297:Male; D010375:Pedigree; D012044:Regression Analysis; D012098:Reproduction; D012720:Severity of Illness Index