Internal dosimetry in the use of radiopharmaceuticals in therapy--science at a crossroads?
Because of expanding therapeutic applications, radionuclide dosimetry is in a stage of reference "man" based system to systems for "patient-specific dosimetry." Although the challenges for the latter system are substantial, patient-specific radiation dosimetry has greater relevance to treatment planning.
Stabin
M G
MG
Universidade Federal de Pernambuco, Departamento de Energia Nuclear Recife, Brazil.
D000328:Adult; D000465:Algorithms; D001853:Bone Marrow / Q000528:radiation effects; D001842:Bone and Bones / Q000528:radiation effects; D005260:Female; D014644:Genetic Variation; D006801:Humans; D018796:Immunoconjugates / Q000032:analysis / Q000493:pharmacokinetics; D008297:Male; D008953:Models, Anatomic; D008954:Models, Biological; D009928:Organ Specificity; D016499:Radioimmunotherapy; D011874:Radiometry / Q000379:methods* / Q000592:standards; D019275:Radiopharmaceuticals / Q000032:analysis* / Q000493:pharmacokinetics; D011879:Radiotherapy Dosage; D014018:Tissue Distribution
D018796:Immunoconjugates; D019275:Radiopharmaceuticals