Electromagnetic therapeutic angiogenesis: the next step.
Therapeutic angiogenesis, in the form of growth factor protein administration or gene therapy, is a new method of treatment for patients with severe coronary and peripheral artery disease not amenable to conventional methods of revascularization. Furthermore, a new experimental strategy increases endogenous angiogenesis in ischemic tissue to induce local 'angiogens' by means of electromagnetic stimulation. Further studies examining the molecular basis and clinical efficacy of electromagnetic angiogenesis are necessary.
Cuevas
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P
Departamento de Investigación, Hospital Ramón y Cajal, Madrid, Spain. pedro.cuevas@hrc.es
Asin-Cardiel
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E
D002545:Brain Ischemia / Q000628:therapy*; D002548:Cerebral Revascularization / Q000379:methods* / Q000639:trends*; D004599:Electric Stimulation Therapy / Q000639:trends*; D006801:Humans; D018919:Neovascularization, Physiologic