Adhesion molecules in early neonatal life.
This study investigated whether serum levels of the adhesion molecules VCAM-1, PECAM-1 and L-selectin, all of which have been implicated in normal immune function, change soon after birth. Moreover, the dependence of serum levels of the above-mentioned adhesion molecules on sex and mode of delivery was studied. In healthy neonates, serum levels of L-selectin, PECAM-1, and VCAM-1 do not change during early neonatal life. Thus, significant differences in their serum concentrations soon after birth might imply inflammatory processes or deranged endothelial homeostasis, serving as possible diagnostic markers.
Malamitsi-Puchner
A
A
Second Department of Obstetrics and Gynecology, University of Athens, Greece.
Tziotis
J
J
Mastorakos
G
G
Protonotariou
E
E
Creatsas
G
G
D015815:Cell Adhesion Molecules / Q000097:blood*; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D019041:L-Selectin / Q000097:blood; D008297:Male; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000097:blood; D012016:Reference Values; D019010:Vascular Cell Adhesion Molecule-1 / Q000097:blood
D015815:Cell Adhesion Molecules; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D019010:Vascular Cell Adhesion Molecule-1; D019041:L-Selectin