title: [The blood immunological indices in rapidly progressing periodontitis (preliminary results)].
abstract: Clinical and immunological parameters were studied in 20 patients with rapidly progressing periodontitis (RPP). Changes in the immune status were as follows: the count of CD3+ cells in peripheral blood increased, the ratio of regulatory helper to suppressor populations (CD4+/CD8+) decreased, and the level of circulating immune complexes increased. A relationship between some clinical and immunological parameters was detected. The detected changes in the immune status of patients with RPP were virtually the same as those in adult patients with typical periodontitis. Further studies are needed for detecting stable criteria of immunological changes, typical of RPP.
authors.forename: A I
authors.initials: AI
authors.lastname: Grudianov
authors.forename: I V
authors.initials: IV
authors.lastname: Bezrukova
mesh_terms: D000328:Adult; D000936:Antigen-Antibody Complex / Q000097:blood; D018450:Disease Progression; D020022:Genetic Predisposition to Disease; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D009911:Oral Hygiene Index; D010518:Periodontitis / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology; D013997:Time Factors
chemical_list: D000936:Antigen-Antibody Complex; D007136:Immunoglobulins
vernacular_title: Immunologicheskie pokazateli krovi pri bystroprogressiruiushchem parodontite (predvaritelnye rezul'taty).