Analogs of glucose-dependent insulinotropic polypeptide with increased dipeptidyl peptidase IV resistance.
Kühn-Wache
K
K
Probiodrug GmbH, Biocenter, Halle, Saale, Germany.
Manhart
S
S
Hoffmann
T
T
Hinke
S A
SA
Gelling
R
R
Pederson
R A
RA
McIntosh
C H
CH
Demuth
H U
HU
D019943:Amino Acid Substitution; D000818:Animals; D001667:Binding, Competitive; D016466:CHO Cells; D006224:Cricetinae; D000242:Cyclic AMP / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2; D018819:Dipeptidyl Peptidase 4 / Q000378:metabolism*; D015195:Drug Design; D005749:Gastric Inhibitory Polypeptide / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D006868:Hydrolysis; D010446:Peptide Fragments / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D011964:Receptors, Gastrointestinal Hormone / Q000187:drug effects / Q000235:genetics / Q000378:metabolism; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D015290:Second Messenger Systems / Q000187:drug effects; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D010446:Peptide Fragments; D011964:Receptors, Gastrointestinal Hormone; D011993:Recombinant Fusion Proteins; D005749:Gastric Inhibitory Polypeptide; C041086:gastric inhibitory polypeptide receptor; D000242:Cyclic AMP; D018819:Dipeptidyl Peptidase 4