Long-term effects of plate osteosynthesis: comparison of four different plates.
Various phenomena have been observed subsequent to plate osteosynthesis, for example, refracture after plate removal. Experimental research has shown that changes in the cortex occur within the first three months after plating and again several months later. These changes are independent of the fracture and take the form of porosis under the plate and excessive bone growth around the plate. Porosis under the plate was regarded until recently as being due to unloading of the bone by the plate, also known as stress shielding. Investigations of the relationship between bone porosis and the changes in periosteal blood supply due to its compression by the plate, however, have been neglected. In this study, the effect of plate properties such as structural stiffness ('unloading'), implant material, and plate contact surface (altered periosteal blood supply) on bone after osteosynthesis were investigated. This was done by comparative histomorphometry of the altered bone in sheep after application of four plates differing in the above-mentioned properties. After plating the sheep tibia with a trapezoid plate with narrow contact surface, significantly larger bone cross sections were observed one year after the operation and considerable bone growth around the plate. The area of early temporary porosis in the cortex under the plate as observed in the first nine weeks and after one year was not significantly different for any particular plate, all of which were applied subperiosteally. The trapezoid plates were easier to remove, thus causing less damage to the bone lamellae along the sides of the plate. The marked increase in bone cross section after one year and the larger areas of bone growth around the trapezoid plates with smaller contact surface can be attributed to the larger grooves cut along the sides of the plates. Cortical porosis was mainly the result of impaired periosteal blood supply which was of equal size in all groups as a result of careful periosteal stripping and subperiosteal plate insertion. It was assumed that applying the plate onto the periosteum would be associated with effects on periosteal blood supply directly related to the plate and consequently cortical porosis. Plate related stress shielding and the implant material had no significant effect on the extent of cortical porosis.
Klaue
K
K
AO ASIF Research Institute.
Fengels
I
I
Perren
S M
SM
D000818:Animals; D001672:Biocompatible Materials; D001860:Bone Plates / Q000009:adverse effects*; D005592:Fracture Fixation / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D017102:Fracture Healing / Q000502:physiology*; D006652:Histological Techniques; D010024:Osteoporosis / Q000209:etiology; D010027:Osteotomy; D010521:Periosteum / Q000098:blood supply*; D012756:Sheep; D013314:Stress, Mechanical; D013977:Tibia
D001672:Biocompatible Materials