title: Symptomatic calcific stenosis of a Toronto stentless porcine valve.
abstract: We describe the calcific structural failure of a Toronto stentless porcine valve (TSPV) which had been used to replace a calcified bicuspid aortic valve in a 46-year-old man. Against expectations, left ventricular hypertrophy persisted and the transvalvular pressure gradient rose to 125 mmHg by 6 years with the patient becoming symptomatic and requiring redo surgery. On removal the TSPV showed atypical calcification of the leaflet hinges and wall. To our knowledge this is the first case reported and it may have implications for long term durability and future surgery using this prosthesis.
authors.affiliation: Royal Brompton Hospital, London, UK.
authors.forename: P D
authors.initials: PD
authors.lastname: Tansley
authors.forename: M N
authors.initials: MN
authors.lastname: Sheppard
authors.forename: J
authors.initials: J
authors.lastname: Pepper
mesh_terms: D000818:Animals; D001024:Aortic Valve Stenosis / Q000601:surgery; D001705:Bioprosthesis / Q000009:adverse effects*; D002114:Calcinosis / Q000209:etiology*; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D012086:Reoperation; D013552:Swine