[Partial re-screening of all negative smears. A method of quality control of pathology department concerning smear screening against cervix cancer].
Partial rescreening of all negative smears is recommended as the most cost-effective method of internal quality control. The method was tested by eight cytotechnologists and the average diagnostic sensitivity, assessed upon their answering of 200 test-smears (150 negative and 50 positive) was 80%, while specificity vas calculated to 95%. Partial rescreening has here-upon been used in daily routine. After one year 21,000 smears have been re-screened. Twenty-nine cases of false negatives, 16 with atypia, eight with koilocytosis, and five cases with dysplasia have been detected, which corresponds to an overall false negative rate on 3%. In five of the 29 false negative cases with dysplasia histological follow-up has shown three cases of CIN III (two carcinoma in situ, one severe dysplasia), one case with CIN II (moderate dysplasia) and one case with CIN I (mild dysplasia). Conclusively, partial rescreening of all negative smears implies an improved quality with reduction of the number of false negative specimens.
Jensen
M L
ML
Randers Centralsygehus, patologisk institut.
Dybdahl
H
H
Svanholm
H
H
D003362:Cost-Benefit Analysis; D003718:Denmark; D005188:False Negative Reactions; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008403:Mass Screening / Q000191:economics / Q000592:standards* / Q000706:statistics & numerical data; D010337:Pathology Department, Hospital / Q000592:standards; D011785:Quality Assurance, Health Care; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000517:prevention & control; D014626:Vaginal Smears / Q000191:economics / Q000592:standards* / Q000706:statistics & numerical data
Partiel rescreening af alle negative "smears". En metode til patologiafdelingens kvalitetskontrol af "smear"-screening mod livmoderhalskraeft.