[The anti-Candida activity of shikon].
Antifungal activity of Shikon, roots of Lithospermum erythrorhizon and Arnebia euchroma was investigated in vitro. The extracts containing the pigments of Ko-shikon or Nan-shikon showed the antifungal activities against Candida albicans. Acetylshikonin, one of these pigments, inhibited the fungal growth at MIC 15.6 micrograms/ml (RPMI24 h) or 3.9 micrograms/ml (YNB24 h).
Sasaki
K
K
Tohoku Pharmaceutical University, Sendai, Japan.
Yoshizaki
F
F
Abe
H
H
D000880:Anthraquinones / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D010860:Pigments, Biological / Q000494:pharmacology*
D000880:Anthraquinones; D004365:Drugs, Chinese Herbal; D010860:Pigments, Biological; C073944:acetylshikonin