title: Coping and medication adherence in bipolar disorder.
abstract: BACKGROUND
  Effective treatment of bipolar disorder depends on medication adherence, yet few correlates of adherence have been identified. The pleasure experienced during some manic episodes may render some individuals reluctant to adhere to medications that reduce these 'highs'. Clinical observers identify denial of the severity or existence of illness as common to both bipolar disorder and addiction. The Alcoholics Anonymous model promotes acceptance as a pathway to abstinence adherence. This report hypothesized that acceptance coping would correlate positively and denial coping would correlate inversely with adherence to mood-stabilizing medication among individuals with bipolar disorder.
  
  
  METHODS
  Thirty-two participants diagnosed with bipolar I disorder were administered scales from the Brief COPE and an adherence self-report measure.
  
  
  RESULTS
  Consistent with hypotheses, curvilinear relationships between acceptance and denial with adherence were detected, suggesting that low levels of acceptance and high levels of denial undermine medication adherence.
  
  
  CONCLUSIONS
  Given the cross-sectional, naturalistic design of the study, no causal inferences can be made.
  
  
  CONCLUSIONS
  The results uncover links between coping styles and adherence in a psychiatric population. The link between acceptance-denial coping, and mature, self-supportive behavior may point the way towards more effective psychosocial interventions.
authors.affiliation: Department of Psychology, University of Miami, PO Box 248185, Coral Gables, FL 33124-2070, USA. wgreenhouse@umiami.ir.miami.edu
authors.forename: W J
authors.initials: WJ
authors.lastname: Greenhouse
authors.forename: B
authors.initials: B
authors.lastname: Meyer
authors.forename: S L
authors.initials: SL
authors.lastname: Johnson
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D018692:Antimanic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D003717:Denial, Psychological; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000523:psychology*
chemical_list: D018692:Antimanic Agents