title: Primary cutaneous B-cell lymphoma of the leg in a chronic lymphedematous extremity.
abstract: This is a case report of a woman who had chronic lymphedema on one leg and who developed a primary cutaneous large B-cell lymphoma of the leg at that site. She received radiotherapy and did not show any systemic involvement thereafter. Other neoplasms may appear in a clinical setting of chronic lymphedema, namely, lymphangiosarcoma (Stewart-Treves), melanoma, and metastatic carcinoma. There are four other reports in the English literature of cutaneous lymphoma arising in an extremity with chronic lymphedema.
authors.affiliation: Department of Dermatology, University of Puerto Rico, School of Medicine, San Juan 00936-5067, USA.
authors.forename: D
authors.initials: D
authors.lastname: Torres-Paoli
authors.forename: J L
authors.initials: JL
authors.lastname: Sánchez
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007866:Leg; D008209:Lymphedema / Q000150:complications* / Q000473:pathology / Q000628:therapy; D016393:Lymphoma, B-Cell / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D016403:Lymphoma, Large B-Cell, Diffuse / Q000209:etiology* / Q000473:pathology; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology / Q000628:therapy