Seventeen more novel HLA-A locus alleles.
This paper describes seventeen novel HLA-A locus alleles: A*0106, *0235, *0236, *0237, *1105, *2302, *2303, *24032, *2422, *2424, *2503, *2613, *3007, *3203, *3204, *6809 and *6810. All alleles were identified due to unexpected probe reaction patterns during routine SSOP typing. Exons 2 and 3 of these alleles were subsequently characterized by DNA sequencing. The alleles represent a shuffling of sequence motifs, likely by interallelic conversion, expanding the diversity of the HLA system.
Ellis
J
J
Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, USA.
Steiner
N
N
Kosman
C
C
Henson
V
V
Mitton
W
W
Koester
R
R
Ng
J
J
Hartzman
R J
RJ
Hurley
C K
CK
D000483:Alleles; D001483:Base Sequence; D005091:Exons / Q000235:genetics; D014644:Genetic Variation; D015234:HLA-A Antigens / Q000235:genetics* / Q000276:immunology; D006801:Humans; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA
D015234:HLA-A Antigens