Effects of conjugated linoleic acid. 2. Embryonic and neonatal growth and circulating lipids.
The present study was designed to investigate the effects of conjugated linoleic acid (CLA) on yolk usage and circulating very low density lipoproteins (VLDL) during incubation (Day 15) and through 6 d post-hatch. Eggs enriched with CLA were obtained from hens subjected to the following treatments. Group A hens served as the control group, Group B hens received 1 g CLA every other day, Group C hens received 1 g CLA every 4th d, and Group D hens were sham-supplemented with 1 g safflower oil every other day. Enrichment with CLA did not effect fertility, hatch of fertile, BW, or yolk-free BW of embryos or chicks. However, there were significant changes in relative yolk sac weight (RYW) and composition of circulating VLDL particles. Across all dietary treatments (Groups B, C, and D), 15-d embryos had smaller RYW compared with Group A embryos; this difference remained through 2 d posthatch. During that period (15 d of incubation through 2 d posthatch), however, embryos and chicks from Group B hens exhibited a unique absorption pattern such that little to no yolk was utilized between hatch and 2 d posthatch, a period normally characterized by high yolk lipid utilization. Similar to the RYW effects, VLDL particles were also altered by hen-induced treatment. Specifically, at hatch, chicks from Group A hens had the highest percentage of triglycerides (TG) within their VLDL particles compared with chicks from hens under all other treatments. This trend in VLDL particles was continued at 4 d posthatch. The present study demonstrates that CLA enrichment of eggs alters relative yolk sac absorption and the composition of circulating VLDL particles.
Latour
M A
MA
Department of Animal Sciences, Purdue University, West Lafayette, Indiana 47907-1151, USA. gator@purdue.edu
Devitt
A A
AA
Meunier
R A
RA
Stewart
J J
JJ
Watkins
B A
BA
D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development*; D001835:Body Weight; D002642:Chick Embryo / Q000254:growth & development*; D002645:Chickens / Q000097:blood* / Q000254:growth & development; D002788:Cholesterol Esters / Q000097:blood; D004530:Egg Yolk / Q000187:drug effects; D005260:Female; D019787:Linoleic Acid / Q000494:pharmacology*; D008055:Lipids / Q000097:blood*; D008079:Lipoproteins, VLDL / Q000097:blood; D009929:Organ Size / Q000187:drug effects; D010743:Phospholipids / Q000097:blood; D014280:Triglycerides / Q000097:blood; D015017:Yolk Sac / Q000033:anatomy & histology
D002788:Cholesterol Esters; D008055:Lipids; D008079:Lipoproteins, VLDL; D010743:Phospholipids; D014280:Triglycerides; D019787:Linoleic Acid