title: Bronchial artery revascularization improves tracheal anastomotic healing after lung transplantation.
abstract: The study aimed to clarify the role of direct bronchial artery revascularization (BAR) after en bloc double-lung (DLT) and heart-lung transplantation (HLT). Group I comprised eight patients with en bloc DLT or HLT and successful BAR, while group II included 14 DLT or HLT cases without BAR or with failed BAR. From these groups, 2 subgroups were extracted: group III, including 6 cases of en bloc DLT with successful BAR and group IV 10 HLT cases without or with failed BAR. Airway healing was evaluated at bronchoscopy and patency of BAR with angiography. Pulmonary viral, bacterial and fungal infections, rejections and bronchiolitis obliterans syndrome (BOS) were registered. Tracheal healing at 2 weeks and 3 months was better in group I than in group 1 (p = 0.003 and p = 0.05, respectively). Compared with group IV, tracheal anastomotic healing at 2 weeks was better in group III (p = 0.007) and tended to be better also after 3 months (p = 0.07). The incidence of infections, rejection or BOS did not differ between groups I and II. BAR thus improved healing of tracheal anastomosis.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Helsinki University Central Hospital, Finland. timo.hyytinen@huch.fi
authors.forename: T A
authors.initials: TA
authors.lastname: Hyytinen
authors.forename: L J
authors.initials: LJ
authors.lastname: Heikkilä
authors.forename: K A
authors.initials: KA
authors.lastname: Verkkala
authors.forename: J T
authors.initials: JT
authors.lastname: Sipponen
authors.forename: T L
authors.initials: TL
authors.lastname: Vainikka
authors.forename: M
authors.initials: M
authors.lastname: Halme
authors.forename: P E
authors.initials: PE
authors.lastname: Hekali
authors.forename: P E
authors.initials: PE
authors.lastname: Keto
authors.forename: S P
authors.initials: SP
authors.lastname: Mattila
mesh_terms: D000293:Adolescent; D000328:Adult; D000714:Anastomosis, Surgical; D001980:Bronchi / Q000601:surgery*; D001981:Bronchial Arteries; D005260:Female; D006801:Humans; D016040:Lung Transplantation / Q000379:methods; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D014132:Trachea / Q000601:surgery*; D014945:Wound Healing