[The structure of the optic nerve in experimental glaucoma and in the means for its treatment].
Using light and electron microscopy disorders of structure of the optic nerve were studied in rabbits with adrenaline induced glaucoma and after the action of antioxidants (Emoxipine, Erisode) used for preventive and medical purposes. Changes in glaucoma and after administration of drugs in axons and their myelinated sheath were similar but differently pronounced in right and left eye of the same animal. Positive effect of Erisode used for preventive and medical purposes was noted. Emoxipine enhanced the disturbances in optic nerve structure.
Ivanova
V F
VF
Laboratory of Medico-Biological Research, I. I. Mechnikov State Medical Academy, St. Petersburg.
Mikheeva
E A
EA
Karelina
V E
VE
Alekseev
V N
VN
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D004837:Epinephrine; D005901:Glaucoma / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology*; D008854:Microscopy, Electron; D009900:Optic Nerve / Q000187:drug effects / Q000473:pathology*; D010847:Picolines / Q000494:pharmacology / Q000627:therapeutic use; D011817:Rabbits; D013997:Time Factors
D000975:Antioxidants; D010847:Picolines; C009820:6-methyl-2-ethyl-3-hydroxypyridine; D004837:Epinephrine
Stroenie zritel'nogo nerva pri éksperimental'noĭ glaukome i nekotorykh sposobakh ee lecheniia.