title: [Effect of dark adaptation on retinal blood flow].
abstract: OBJECTIVE
  Laser Doppler measurements performed immediately after the transition from dark adaptation (DA) to light led to the hypothesis that retinal blood flow, Fret, is increased during DA, but the use of visible lasers had prevented measurements during DA. Our aim was to test this hypothesis by measuring Fret during and after DA.
  
  
  METHODS
  Fret in retinal vessels at the optic disk surface was recorded quasi-continuously in one eye of 6 normal subjects (age 27 to 60 years) using a laser Doppler flowmeter in the near-infrared (810 nm). Measurements were performed during light (baseline), various periods of DA and again during light. DA lasted between 2 and 32 min.
  
  
  RESULTS
  Average Fret for the 6 subjects did not change significantly (-2.7 +/- 8% sd, p > 0.05) during the various periods of DA, as determined from linear regressions of the flux versus time. Following the transition from DA to light, there was, in most cases, a rapid transient increase of the flux, which reached an average value of 37 +/- 10% above the pre-transition value and peaked at 30-60 sec after the transition.
  
  
  CONCLUSIONS
  These results do not support the hypothesis that Fret in normal volunteers is increased during DA. Rather, they strongly suggest that the transient increase in flux observed after DA is induced by the transition from dark to light (FNSRS #3200-043157 et CNR, It. #95.01715.CT04).
authors.affiliation: Institut de Recherche en Ophtalmologie, Sion, Suisse.
authors.forename: C E
authors.initials: CE
authors.lastname: Riva
authors.forename: E
authors.initials: E
authors.lastname: Logean
authors.forename: B L
authors.initials: BL
authors.lastname: Petrig
authors.forename: B
authors.initials: B
authors.lastname: Falsini
mesh_terms: D000221:Adaptation, Ocular / Q000502:physiology*; D000328:Adult; D003623:Dark Adaptation / Q000502:physiology*; D005123:Eye / Q000098:blood supply*; D006801:Humans; D007259:Infrared Rays; D017078:Laser-Doppler Flowmetry; D008875:Middle Aged; D012039:Regional Blood Flow; D012171:Retinal Vessels / Q000502:physiology*
vernacular_title: Effet de l'adaptation à l'obscurité sur le flux rétinien.