title: [Chromosomal instability in offspring of voles in unfavorable radiation zones].
abstract: A high frequency of cells having chromosomal aberrations was shown to be preserved in the first generation of laboratory offspring of common voles, whose ancestors were captured near the East Ural radioactive track (EURT). In F2 and F3, a decrease in frequency was observed. Most likely, the cytogenetic effects observed were caused by environmental contamination with plutonium in the locality of capture. An increased chromosomal instability observed in the first laboratory generation of nonirradiated common voles was caused by reversible modifications in the expression of mutator genes inherited from parents exposed to alpha-irradiation rather than by classic mutations occurred in specific loci.
authors.affiliation: Institute of Plant and Animal Ecology, Russian Academy of Sciences, Yekaterinburg, Russia. gileva@ipae.uran.ru
authors.forename: E A
authors.initials: EA
authors.lastname: Gileva
authors.forename: D Iu
authors.initials: DIu
authors.lastname: Nokhrin
authors.forename: V I
authors.initials: VI
authors.lastname: Starichenko
mesh_terms: D000818:Animals; D003411:Arvicolinae / Q000235:genetics*; D002869:Chromosome Aberrations; D005260:Female; D008297:Male; D009154:Mutation; D011848:Radioactive Pollutants
chemical_list: D011848:Radioactive Pollutants
vernacular_title: Khromosomnaia nestabil'nost' u potomkov polevok iz zony radiatsionnogo neblagopoluchiia.