title: Frequency of stroke in Europe: A collaborative study of population-based cohorts. ILSA Working Group and the Neurologic Diseases in the Elderly Research Group. Italian Longitudinal Study on Aging.
abstract: The authors estimated stroke frequency in Europe using data from six population-based studies that were analyzed separately and also pooled. Overall, these surveys comprised 19,132 individuals age 55 years and older for the prevalence analyses, and 35,577 person-years for the incidence analyses. The overall prevalence of stroke, age- and sex-adjusted to the 1991 European population, was 4.84% (95% CI 4.47 to 5.21) in individuals age 65 to 84 years and 7.06% (95% CI 6.52 to 7.60) in those 75 years and older. Age- and sex-specific rates did not differ substantially across the studies. Incidence rates of first-ever stroke rose markedly with age, and the pooled results confirmed that incidence keeps increasing even at 90 years of age and older. The overall age- and sex-standardized incidence rates were 8.72 per 1000 person-years (95% CI 7.47 to 10.06) for individuals age 65 to 84 years, and 17.31 per 1000 person-years (95% CI 14.79 to 20.02) for those age 75 years and over.
authors.affiliation: National Research Council (CNR-CSFET), Italian Longitudinal Study on Aging, Florence, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Di Carlo
authors.forename: L J
authors.initials: LJ
authors.lastname: Launer
authors.forename: M M
authors.initials: MM
authors.lastname: Breteler
authors.forename: L
authors.initials: L
authors.lastname: Fratiglioni
authors.forename: A
authors.initials: A
authors.lastname: Lobo
authors.forename: J
authors.initials: J
authors.lastname: Martinez-Lage
authors.forename: R
authors.initials: R
authors.lastname: Schmidt
authors.forename: A
authors.initials: A
authors.lastname: Hofman
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007326:Institutionalization; D008297:Male; D015995:Prevalence; D012737:Sex Factors; D020521:Stroke / Q000453:epidemiology*