title: Life-table analysis of primary and assisted success following endoluminal repair of abdominal aortic aneurysms: the role of supplementary endovascular intervention in improving outcome.
abstract: OBJECTIVE
  the aim of this study was to analyse the effect of supplementary endovascular intervention on the outcome of primary endoluminal repair of abdominal aortic aneurysm (AAA).
  
  
  METHODS
  between May 1992 and December 1998, 266 patients underwent endoluminal repair of AAA. Minimum period of follow-up was 6 months. Those patients in whom the endoprosthesis could not be deployed were converted to open repair at the primary operation. Patients developing an early endoleak, within 31 days, were treated by a period of observation and secondary endovascular intervention in persistent cases. Patients developing a late endoleak were treated similarly, without a period of observation. Outcome was analysed by the life-table method. Primary success was defined as exclusion of the aneurysm from the circulation resulting from the original operation. Assisted success occurred when aneurysms with endoleaks became excluded from the circulation as a result of supplementary endovascular intervention.
  
  
  RESULTS
  endoluminal repair failed in 17 patients requiring conversion to open repair at the original operation. Supplementary endovascular intervention was undertaken in 26 patients, with early endoleaks (n=6) and late endoleaks (n=20). Interventions involved deployment of secondary endoluminal grafts within the primary grafts (n=22), and coil embolisation (n=4). Successful exclusion of the aneurysm sac was achieved in 22 of 26 (85%) patients undergoing supplementary endovascular procedures. Conditional cumulative incidence of primary graft failure and secondary graft failure in the presence of all-cause mortality at 6 years was 47% and 25% respectively.
  
  
  CONCLUSIONS
  supplementary endovascular intervention is an important adjunct to endoluminal AAA repair with the potential to improve outcome and avoid conversion to open repair. Successful supplementary endovascular intervention was achieved in 85% of patients in whom it was attempted. Life-table analysis showed these supplementary procedures to be durable in the long term.
authors.affiliation: Department of Surgery, University of Sydney, Australia.
authors.forename: J
authors.initials: J
authors.lastname: May
authors.forename: G H
authors.initials: GH
authors.lastname: White
authors.forename: R
authors.initials: R
authors.lastname: Waugh
authors.forename: P
authors.initials: P
authors.lastname: Petrasek
authors.forename: X
authors.initials: X
authors.lastname: Chaufour
authors.forename: M
authors.initials: M
authors.lastname: Arulchelvam
authors.forename: M S
authors.initials: MS
authors.lastname: Stephen
authors.forename: J P
authors.initials: JP
authors.lastname: Harris
mesh_terms: D000368:Aged; D000792:Angiography; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation; D002423:Cause of Death; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D015994:Incidence; D015993:Life Tables; D008297:Male; D019106:Postoperative Hemorrhage / Q000209:etiology; D011475:Prosthesis Failure; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome