Concordance between functional magnetic resonance imaging and intraoperative language mapping.
Although the correspondence between functional-magnetic resonance imaging (fMRI) representations of the sensorimotor cortex and intraoperative electrophysiology (including somatosensory evoked potential, SSEP, recordings and direct cortical stimulation) has been reported, a similar correspondence between fMRI and intraoperative localization of the language-sensitive cortex is not as well established. The aim of the present study was to evaluate the concordance between fMRI and intraoperative electrophysiology with respect to the localization of the language-sensitive and sensorimotor cortices. We present the results of 21 patients who underwent language and sensorimotor mapping by fMRI and intraoperative electrophysiology including SSEP recordings (n = 21), direct cortical stimulation of motor cortex (n = 15) and direct cortical stimulation of Broca's and Wernicke's area (n = 5). When responses were obtained with both methods, localization of function concurred in all cases. These observations suggest that fMRI represents a reliable preoperative tool for the identification of language-sensitive areas.
Ruge
M I
MI
Department of Neurology, Memorial Sloan-Kettering Cancer Center, Weill Medical College of Cornell University, New York, NY, USA. william.orrison@hsc.utah.edu
Victor
J
J
Hosain
S
S
Correa
D D
DD
Relkin
N R
NR
Tabar
V
V
Brennan
C
C
Gutin
P H
PH
Hirsch
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D001931:Brain Mapping; D002648:Child; D004558:Electric Stimulation; D005073:Evoked Potentials, Somatosensory; D005260:Female; D005625:Frontal Lobe / Q000033:anatomy & histology / Q000502:physiology* / Q000601:surgery; D006801:Humans; D007432:Intraoperative Period; D007802:Language; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010296:Parietal Lobe / Q000503:physiopathology / Q000601:surgery; D011300:Preoperative Care / Q000379:methods; D015173:Supratentorial Neoplasms / Q000601:surgery; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000502:physiology* / Q000503:physiopathology / Q000601:surgery; D013788:Thalamus / Q000503:physiopathology / Q000601:surgery