title: Parvovirus as a differential diagnosis of hydrops fetalis in the first trimester.
abstract: We report a case of fetal parvovirus B19 infection which appears to have resulted in hydrops in the first trimester. An ultrasound scan performed at the booking visit of a woman in the first trimester showed generalised oedema. Karyotyping to exclude a fetal abnormality was normal. Maternal radioimmunoassay serological investigations showed parvovirus B19 IgG and IgM. Post-mortem analysis revealed intranuclear inclusion bodies typical of parvovirus in the erythroid cells in the liver and in the myocardium.
authors.affiliation: Department of Maternal and Fetal Medicine, St. Michael's Hospital, Bristol, UK.
authors.forename: K
authors.initials: K
authors.lastname: Sohan
authors.forename: S
authors.initials: S
authors.lastname: Carroll
authors.forename: D
authors.initials: D
authors.lastname: Byrne
authors.forename: M
authors.initials: M
authors.lastname: Ashworth
authors.forename: P
authors.initials: P
authors.lastname: Soothill
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D005315:Fetal Diseases / Q000821:virology*; D005865:Gestational Age; D006801:Humans; D015160:Hydrops Fetalis / Q000000981:diagnostic imaging / Q000821:virology*; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007621:Karyotyping; D010322:Parvoviridae Infections / Q000175:diagnosis*; D016732:Parvovirus B19, Human / Q000276:immunology; D011247:Pregnancy; D016216:Ultrasonography, Prenatal
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M