title: Single centre experience on primary correction of common arterial trunk: overall survival and freedom from reoperation after more than 15 years.
abstract: OBJECTIVE
  To identify predictors of early and late outcomes of common arterial trunk (CAT) after primary surgical correction, such as clinical state prior to surgery, age and weight at presentation, implications of truncal valve abnormalities and associated anomalies of this complex congenital malformation.
  
  
  METHODS
  A consecutive series of 106 patients, operated between 1976 and 1998, were reviewed retrospectively. Using the 'Van Praagh' classification, 59 patients presented as A1, 33 as A2, six as A3, and eight as A4. The mean age at operation was 8.6 months (range, 14 days-8.9 years; median, 4.4 months), and the mean weight was 5.2 kg (range, 2.5-30.8 kg; median, 4.4 kg). At the time of operation, 32 patients had congestive heart failure, five were on ventilator support for less than 1 week, and 21 for more than 1 week.
  
  
  RESULTS
  Between 1976 and 1989, the early mortality was 21%, and between 1990 and 1998, it dropped to 13%. After 1, 10 and 15 years, the overall survival was 66, 61 and 59%. The 1, 5, 10 and 15 year freedom from reoperation was 82, 60, 22 and 10%, respectively. Clinical condition prior to intervention, truncal valvar dysfunction, and coronary anomalies were significantly associated with poor surgical outcome, whereas weight and age at presentation in our series were not.
  
  
  CONCLUSIONS
  In the current era of paediatric cardiac surgery, primary surgical repair of CAT can be carried out with reasonable early and late mortality. However, our data suggest that a high incidence of reoperation, mainly due to the outgrowth and failure of the conduit, has to be expected. The patient's clinical state after diagnosis is decisive for the timing of intervention.
authors.affiliation: Department of Cardio-thoracic Surgery, German Heart Centre at the Technical University, Lazarettstrasse 36, 80636, Munich, Germany. schreiber@dhm.mhn.de
authors.forename: C
authors.initials: C
authors.lastname: Schreiber
authors.forename: A
authors.initials: A
authors.lastname: Eicken
authors.forename: G
authors.initials: G
authors.lastname: Balling
authors.forename: M
authors.initials: M
authors.lastname: Wottke
authors.forename: G
authors.initials: G
authors.lastname: Schumacher
authors.forename: S
authors.initials: S
authors.lastname: Un Paek
authors.forename: H
authors.initials: H
authors.lastname: Meisner
authors.forename: J
authors.initials: J
authors.lastname: Hess
authors.forename: R
authors.initials: R
authors.lastname: Lange
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012086:Reoperation; D016896:Treatment Outcome; D014339:Truncus Arteriosus, Persistent / Q000401:mortality / Q000601:surgery*