Asymptomatic uveitis in young people with inflammatory bowel disease.
OBJECTIVE
To ascertain the prevalence of uveitis in a population of pediatric patients with inflammatory bowel disease without ocular symptoms.


METHODS
We prospectively evaluated all young people who came to the pediatric gastroenterology clinic with endoscopically proven inflammatory bowel disease between March 1994 and June 1995. All the patients were examined for evidence of ocular manifestations of inflammatory bowel disease. The examination consisted of slit-lamp examination, tonometry, and indirect ophthalmoscopy. None of the patients had visual or ocular symptoms. Eighteen patients had Crohn's disease and 14 had ulcerative colitis.


RESULTS
Of the 32 patients evaluated, four (12.5%) had evidence of asymptomatic ocular inflammation, defined as anterior chamber cell and flare. All patients with ocular inflammation were male. Three of these four male patients had Crohn's disease; the other had ulcerative colitis. Five patients had posterior subcapsular cataract, one had esotropia and amblyopia, and one had unilateral high myopia.


CONCLUSIONS
The prevalence of asymptomatic uveitis in our population of young people with inflammatory bowel disease was 12.5%. These findings suggest the need for a screening ophthalmologic examination to rule out occult eye disease in young people with inflammatory bowel disease.
Rychwalski
P J
PJ
Department of Ophthalmology, St. Louis University Eye Institute, St. Louis University School of Medicine, USA.
Cruz
O A
OA
Alanis-Lambreton
G
G
Foy
T M
TM
Kane
R E
RE
D000293:Adolescent; D000328:Adult; D000867:Anterior Chamber / Q000473:pathology; D002452:Cell Count; D002648:Child; D002675:Child, Preschool; D003093:Colitis, Ulcerative / Q000150:complications* / Q000453:epidemiology / Q000473:pathology; D003113:Colonoscopy; D003424:Crohn Disease / Q000150:complications* / Q000453:epidemiology / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009887:Ophthalmoscopy; D015995:Prevalence; D011446:Prospective Studies; D012720:Severity of Illness Index; D014606:Uveitis, Anterior / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D014792:Visual Acuity