[The adaptational properties and immunoregulatory action of a preparation of proteolytic enzymes in experimental stress].
The use of the experimental model of the development of acute secondary immunodeficiency, accompanied by the redistribution of immunoglobulins from plasma to blood cells, for evaluating the effect of immunomodulation is substantiated. The preparation of proteolytic enzymes Wobenzym [correction of "Vobenzyme"] has been shown to produce significant and dose-dependent decrease the sorption of immunoglobulins on mouse cells in the process of swimming.
Suzdal'nitskiĭ
R S
RS
Research Institute of Physical Training, Moscow, Russia.
Levando
V A
VA
Emel'ianov
B A
BA
Sokolov
Ia A
IaA
D000222:Adaptation, Physiological / Q000187:drug effects*; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000285:Administration, Rectal; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D006867:Hydrolases / Q000627:therapeutic use*; D007136:Immunoglobulins / Q000097:blood / Q000187:drug effects; D007274:Injections, Intraperitoneal; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D012431:Rutin / Q000627:therapeutic use*; D013312:Stress, Physiological / Q000188:drug therapy* / Q000276:immunology; D013550:Swimming
D000276:Adjuvants, Immunologic; D004338:Drug Combinations; D007136:Immunoglobulins; D012431:Rutin; C023295:Wobenzym; D006867:Hydrolases
Adaptatsionnye svoĭstva i immunoreguliatornoe deĭstvie preparata proteoliticheskikh fermentov pri éksperimental'nom stresse.