title: Frequency data on four tetrameric STR loci D18S1270, D14S608, D16S3253 and D21S1437 in a Korean population.
abstract: We present the results of a population study in Korea for four new tetrameric short tandem repeat (STR) loci employing multiplex PCR amplification, polyacrylamide gel electrophoresis of the PCR products and silver staining, which allow single base pair resolution and rapid typing. The loci tested were D18S1270, D14S608, D16S3253 and D21S1437 and all loci showed no significant deviations from Hardy-Weinberg equilibrium in more than 100 unrelated Koreans. This allelic frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a multiplex PCR based DNA profile in the Korean population.
authors.affiliation: Department of Molecular Biology, and Research Center for Cell Differentiation, Seoul National University, Korea.
authors.forename: M
authors.initials: M
authors.lastname: Choi
authors.forename: J H
authors.initials: JH
authors.lastname: Kim
authors.forename: D H
authors.initials: DH
authors.lastname: Lee
authors.forename: S H
authors.initials: SH
authors.lastname: Lee
authors.forename: H M
authors.initials: HM
authors.lastname: Rho
mesh_terms: D001483:Base Sequence; D016002:Discriminant Analysis; D004591:Electrophoresis, Polyacrylamide Gel; D005787:Gene Frequency / Q000235:genetics*; D005819:Genetic Markers; D006801:Humans; D007723:Korea; D018598:Minisatellite Repeats / Q000235:genetics*; D008969:Molecular Sequence Data; D010334:Paternity; D016133:Polymerase Chain Reaction / Q000379:methods; D011110:Polymorphism, Genetic / Q000235:genetics; D015203:Reproducibility of Results
chemical_list: D005819:Genetic Markers