Alzheimer's disease. Closing in on gamma-secretase.
De Strooper
B
B
D000544:Alzheimer Disease / Q000201:enzymology*; D053829:Amyloid Precursor Protein Secretases; D016229:Amyloid beta-Peptides / Q000378:metabolism; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D000818:Animals; D016282:Aspartic Acid Endopeptidases; D010450:Endopeptidases / Q000009:adverse effects / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D008565:Membrane Proteins / Q000009:adverse effects / Q000378:metabolism*; D051379:Mice; D053764:Presenilin-1; D053766:Presenilin-2
D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor; D004791:Enzyme Inhibitors; D008565:Membrane Proteins; D053764:Presenilin-1; D053766:Presenilin-2; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; D016282:Aspartic Acid Endopeptidases; C509282:Bace1 protein, mouse