title: [Malignant adrenal cortical neoplasms. Report of 22 cases].
abstract: OBJECTIVE
  Analysis of the treatment of a series of patients with adrenal cortical carcinoma.
  
  
  METHODS
  This series consists of 22 patients (15 women and 7 men) with a mean age of 35 years (range: 23 to 58 years). 55% of patients had a non-secreting tumour; 45% of tumours were associated with excessive hormonal secretion. The tumour was located on the right side in 12 cases and on the left side in 11 cases (the tumour was bilateral in 1 case). Ultrasound and CT were sufficient for localization of the tumour. The patients were classified as stage I: 3 cases, stage II: 2 cases, stage III.: 8 cases, stage IV: 9 cases, according to MacFarlane's classification.
  
  
  RESULTS
  Adrenalectomy was performed in 18 patients. Two patients died during the operation and another 8 died within the first four years. Eight patients are currently alive, including 7 with no signs of recurrence; one patient presented a large local recurrence 39 months after adrenalectomy.
  
  
  CONCLUSIONS
  Surgery remains the only effective treatment at the present time. The diagnosis of adrenal cortical carcinoma must be made as early as possible.
authors.affiliation: Clinique Urologique A, Hôpital Avicenne, Rabat, Maroc.
authors.forename: A
authors.initials: A
authors.lastname: Benchekroun
authors.forename: M
authors.initials: M
authors.lastname: Ghadouane
authors.forename: M
authors.initials: M
authors.lastname: Alami
authors.lastname: Kasmaoui el-H
authors.forename: L
authors.initials: L
authors.lastname: Benslimane
authors.forename: M
authors.initials: M
authors.lastname: Faik
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000601:surgery*; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
vernacular_title: Cortico-surrénalomes malins. A propos de 22 cas.