title: Intratumoral consumption of indium-111-labeled platelets in a child with splenic hemangioma and thrombocytopenia.
abstract: The authors report Kasabach-Merritt syndrome (KMS) in a patient with thrombocytopenia and splenic hemangioma. A 13-month-old boy with a history of anemia, thrombocytopenia, and abdominal mass was admitted to the hospital. The scintigraphic studies showed that a large mass contiguous to the spleen was responsible for the platelet uptake. After partial splenectomy, the platelet count returned to normal. This report of KMS in a child with splenic hemangioma suggests that the scintigraphic studies are mandatory to confirm diagnosis. Indium-111-labeled platelets are useful in identifying hemangiomatous sequestration of platelets in patients with thrombocytopenia.
authors.affiliation: Unit of Pediatric Hematology and Oncology, Université de Rennes, France.
authors.forename: C
authors.initials: C
authors.lastname: Pampin
authors.forename: A
authors.initials: A
authors.lastname: Devillers
authors.forename: C
authors.initials: C
authors.lastname: Treguier
authors.forename: B
authors.initials: B
authors.lastname: Fremond
authors.forename: A
authors.initials: A
authors.lastname: Moisan
authors.forename: J
authors.initials: J
authors.lastname: Goasguen
authors.forename: E
authors.initials: E
authors.lastname: Le Gall
mesh_terms: D000740:Anemia / Q000209:etiology; D001792:Blood Platelets; D006392:Hemangioma, Cavernous / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D007205:Indium Radioisotopes; D007223:Infant; D008297:Male; D011877:Radionuclide Imaging; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D013577:Syndrome; D013921:Thrombocytopenia / Q000209:etiology*
chemical_list: D007205:Indium Radioisotopes