title: Vertebral osteophytosis and vertebral deformities in an elderly population sample.
abstract: OBJECTIVE
  We investigated the association between vertebral osteophytosis and vertebral deformities in an elderly population sample, and the influence of some risk factors on spinal osteophytosis and deformities.
  
  
  METHODS
  A population sample of 280 women and 263 men, all Zagreb residents older than 45 years, participated in the study. Radiographs of the thoracic and lumbar spine were evaluated for the presence of osteophyte formation and vertebral deformities. Osteophyte size was graded on a scale from 0 to 4. Vertebral deformities were determined by the semiquantitative method of McCloskey. The chi-square test was used to analyse the association between vertebral osteophytes and deformities, and the influence of several risk factors was investigated by discriminate analysis.
  
  
  RESULTS
  The prevalence of vertebral osteophytosis was 47.9% in men (36.5% in the thoracic and 21.3% in the lumbar spine) and 56.0% in women (36.0% in the thoracic and 23.9% in the lumbar spine). The prevalence of vertebral deformities was 8.3% in men (5.3% in the thoracic and 3.4% in the lumbar spine) and 12.5% in women (7.9% in the thoracic and 5.4% in the lumbar segment). There was a significant association between deformities and osteophytosis on the lumbar segment of the spine (P = 0.0240 men, P = 0.0152 women). Analysing the influence of several risk factors, age was found to be the most associated with both vertebral deformities and osteophytosis. Obesity was significantly associated with osteophytosis.
  
  
  CONCLUSIONS
  We found a significant association between vertebral osteophytosis and deformities in the lumbar segment and no relationship in the thoracic segment. This implicates different etiologies of vertebral deformities in the thoracic and lumbar spine.
authors.affiliation: Institute for Medical Research and Occupational Health, Zagreb, Croatia. cvijetic@imi.hr
authors.forename: S
authors.initials: S
authors.lastname: Cvijetić
authors.forename: E
authors.initials: E
authors.lastname: McCloskey
authors.forename: M
authors.initials: M
authors.lastname: Korsić
mesh_terms: D017677:Age Distribution; D000368:Aged; D015992:Body Mass Index; D016009:Chi-Square Distribution; D017523:Croatia / Q000453:epidemiology; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000453:epidemiology; D015995:Prevalence; D011859:Radiography; D018570:Risk Assessment; D012494:Sampling Studies; D017678:Sex Distribution; D013128:Spinal Osteophytosis / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000473:pathology; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology*