title: Prediction of walking function in stroke patients with initial lower extremity paralysis: the Copenhagen Stroke Study.
abstract: OBJECTIVE
  The majority of stroke patients with initial leg paralysis do not regain independent walking. We characterize the minority who, despite initial leg paralysis, regained independent walking.
  
  
  METHODS
  Consecutive and community based.
  
  
  METHODS
  A stroke unit receiving all stroke patients from a well-defined community.
  
  
  METHODS
  A total of 859 acute stroke patients; 157 (15%) initially had leg paralysis.
  
  
  METHODS
  Scandinavian Stroke Scale (SSS) and Barthel index (BI) on admission and weekly during rehabilitation. Univariate and multivariate statistics were considered.
  
  
  RESULTS
  Of the 157 patients with initial leg paralysis, 84 (60%) died; 73 (40%) survived. Fifteen (21%) survivors regained walking function (the walking group), and 58 (79%) did not (the nonwalking group). The BI on admission was the only factor of significant predictive value (p < .03). Mean admission BI was 50 in the walking group versus 3 in the nonwalking group (p < .001). Age, gender, lesion size, total SSS score, and comorbidity had no predictive value. Within the first week, the walking group gained 3.2 points in the SSS subscore for leg strength versus 0.5 points in the nonwalking group (p < .02).
  
  
  CONCLUSIONS
  Only 10% of stroke patients with initial leg paralysis regained independent walking. In these patients, BI on admission was high and leg strength improved quickly in the first week.
authors.affiliation: Department of Neurology, Bispebjerg Hospital, Copenhagen, Denmark.
authors.forename: A
authors.initials: A
authors.lastname: Wandel
authors.forename: H S
authors.initials: HS
authors.lastname: Jørgensen
authors.forename: H
authors.initials: H
authors.lastname: Nakayama
authors.forename: H O
authors.initials: HO
authors.lastname: Raaschou
authors.forename: T S
authors.initials: TS
authors.lastname: Olsen
mesh_terms: D000368:Aged; D003718:Denmark; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D010264:Paraplegia / Q000401:mortality / Q000534:rehabilitation*; D011379:Prognosis; D011446:Prospective Studies; D020521:Stroke / Q000503:physiopathology; D000071939:Stroke Rehabilitation; D014057:Tomography, X-Ray Computed; D016138:Walking