[Prospective study of JCR-Oligo I of the Child and Adolescence Rheumatology Working Group].
Intra-articular injection of corticosteroids is a powerful anti-inflammatory treatment with relatively few side effects. To date no prospective RCT exists on its use in children with oligoarthritis type I. Thus, in January 2000 the Arbeitsgemeinschaft started a multicenter RCT to compare in children with this diagnosis the initial treatment recommended in the textbooks, which is NSAID plus physiotherapy, with the early use of intra-articular injection of Triamcinolonhexacetonide. In the synovial fluid the presence of cytokines and the specific reactivity of T cells will be explored, and a highly sensitive screening for infectious agents will be performed.
Forster
J
J
St.-Josefskrankenhaus Freiburg.
D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000009:adverse effects; D001171:Arthritis, Juvenile / Q000188:drug therapy* / Q000276:immunology; D002648:Child; D016207:Cytokines / Q000097:blood; D005858:Germany; D006801:Humans; D007270:Injections, Intra-Articular; D011446:Prospective Studies; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D017749:Total Quality Management; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*
D000893:Anti-Inflammatory Agents; D016207:Cytokines; D014222:Triamcinolone Acetonide; C005900:triamcinolone hexacetonide
Prospektive Studie zur JCR-Oligo I der Arbeitsgemeinschaft Kinder- und Jugendrheumatologie.