title: Quality assurance in radiotherapy by identifying standards and monitoring treatment preparation.
abstract: OBJECTIVE
  Due to the complexity of the treatment preparation in radiotherapy, a number of errors go undetected until after the first treatment session. Some of these errors could easily have been noticed before treatment if an objective filter existed in addition to human supervision. With this in mind, a conceptually novel extension to conventional quality assurance procedures was explored to create a global platform monitoring treatment preparation by comparison with the existing local standards.
  
  
  METHODS
  The feasibility of developing such a platform was evaluated for a test case on a cohort of 202 patients having received breast irradiation. By statistical analysis of the treatment parameters, mean values and tolerance levels could be defined for most parameters based on the observed standard deviations. Useful correlations were traced providing us with a means to automatically track errors, the detection of which would otherwise solely depend upon the alertness of the supervisor.
  
  
  CONCLUSIONS
  Apart from its possibilities as a mere quality control tool, the platform, developed in the framework of EQUART (European Quality Assurance Program in Radiotherapy by Monitoring Treatment Preparation), can be incorporated in the treatment preparation chain, providing standard setup values for the simulation. A crucial achievement of EQUART lies in the fact that filtering out of errors occurs prior to treatment initiation.
authors.affiliation: Department of Oncology, Division Radiation Physics, University Hospital Gasthuisberg, Herestraat 49, B-3000, Leuven, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Van Esch
authors.forename: R
authors.initials: R
authors.lastname: Bogaerts
authors.forename: G J
authors.initials: GJ
authors.lastname: Kutcher
authors.forename: D
authors.initials: D
authors.lastname: Huyskens
mesh_terms: D000465:Algorithms; D001943:Breast Neoplasms / Q000532:radiotherapy; D015331:Cohort Studies; D005240:Feasibility Studies; D006801:Humans; D011786:Quality Control; D011829:Radiation Dosage; D011878:Radiotherapy / Q000592:standards*; D011879:Radiotherapy Dosage