title: Changes in directed attention and short-term memory in depression.
abstract: This study examined changes in directed attention and short-term memory in depression using a newly constructed battery of computerized measures. A repeated measures design was used with two sample groups; 25 individuals meeting DSM-IV criteria for Major Depression and a group-matched comparison sample of 27. Both groups were tested at three points in time over a 10-week period. Test-retest reliability of the measures was examined. Profile analysis demonstrated that there were differences between the depressed and comparison groups in both directed attention and short-term memory. Recommendations for specific improvements in the testing battery are discussed. The ability to detect changes in directed attention and short-term memory may have clinical utility in early detection of impending onset of depression or subtle residual symptoms of an acute episode that may impair functioning or signal a relapse.
authors.affiliation: University of Michigan, School of Nursing, 400 N. Ingalls, Room 4352, Ann Arbor, MI 48109, USA. rawill@umich.edu
authors.forename: R A
authors.initials: RA
authors.lastname: Williams
authors.forename: B M
authors.initials: BM
authors.lastname: Hagerty
authors.forename: B
authors.initials: B
authors.lastname: Cimprich
authors.forename: B
authors.initials: B
authors.lastname: Therrien
authors.forename: E
authors.initials: E
authors.lastname: Bay
authors.forename: H
authors.initials: H
authors.lastname: Oe
mesh_terms: D000328:Adult; D001288:Attention; D016022:Case-Control Studies; D003863:Depression / Q000175:diagnosis / Q000523:psychology; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008570:Memory, Short-Term; D009483:Neuropsychological Tests; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D015203:Reproducibility of Results; D013997:Time Factors