title: Comparing the Fused Dichotic Words Test and the Intracarotid Amobarbital Procedure in children with epilepsy.
abstract: The validity of the Fused Dichotic Words Test (FDWT) in predicting the nature of speech representation, as determined by the Intracarotid Amobarbital Procedure (IAP), was examined in a sample of 28 children with epilepsy. Various methods of analysis (difference score, lambda, and lambda(*)), for the FDWT data were calculated and compared. Results showed the validity of the FDWT did not change depending on the method of analysis. The difference scores showed that 18 of the 19 patients with left hemisphere speech obtained right-ear advantages, while the patient with right hemisphere speech showed a left-ear advantage. As a group, patients with left-hemisphere speech obtained a statistically significant right-ear advantage for the lambda and lambda(*) indices, while the patient with right-hemisphere speech showed a left-ear advantage that was also significant for both lambda measures. Patients with bilateral speech, as a group, displayed a non-significant ear advantage. Some of the scores from the left-hemisphere group overlapped with those from patients with bilateral speech representation. Controlling for stimulus dominance effects using the lambda(*) measure did not improve classification accuracy for nature of speech representation based on FDWT scores. Finally, comparison of our data using the laterality index from a similar study, showed scores smaller in magnitude than that found in adults with epilepsy.
authors.affiliation: Department of Psychology, University of Toronto at Mississauga, 3359 Mississauga Road North, Mississauga, Ontario, L5L 1C6, Canada. myra@psych.utoronto.ca
authors.forename: M A
authors.initials: MA
authors.lastname: Fernandes
authors.forename: M L
authors.initials: ML
authors.lastname: Smith
mesh_terms: D000293:Adolescent; D000654:Amobarbital; D000704:Analysis of Variance; D002648:Child; D004292:Dominance, Cerebral; D004827:Epilepsy / Q000523:psychology*; D005260:Female; D007839:Functional Laterality; D018757:GABA Modulators; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests / Q000592:standards*; D011237:Predictive Value of Tests; D013060:Speech / Q000187:drug effects / Q000502:physiology*
chemical_list: D018757:GABA Modulators; D000654:Amobarbital