title: Enhancement characteristics of hepatic focal nodular hyperplasia and its scar by dynamic magnetic resonance imaging.
abstract: OBJECTIVE
  To determine the relationship between the lesion and the scar enhancement characteristic in a series of hepatic Focal Nodular Hyperplasia (FNH) lesions studied with dynamic MR imaging.
  
  
  METHODS
  Nine patients with FNH were studied. The slice showing the largest scar was selected for the dynamic single slice T1-weighted Gradient-echo sequence before and after contrast administration (15 images, one every 20 s). Analysis was performed with ROI measurements in the lesion and the scar. Signal-intensity and enhancement curves were obtained from both structures.
  
  
  RESULTS
  Dynamic MRI showed the typical homogeneous early enhancement of the lesion with delayed enhancement of the scar. The scar enhanced early and vigorously in all cases. Two patterns of enhancement curves were defined. In the parallel pattern, both curves started early, quickly reaching a plateau maintained over time (77.8%). In the divergent pattern the curve of the scar was above the curve of the FNH (22.2%), after the maximum slope was reached, with progressive separation of the curves.
  
  
  CONCLUSIONS
  There is a hypervascular scar enhancement within FNH lesions with either a parallel or divergent course after the maximum early enhancement.
authors.affiliation: Department of Radiology, Doctor Peset University Hospital, Avda Gaspar Aguilar 90, E-46017, Valencia, Spain. marti.lui@gva.es
authors.forename: L
authors.initials: L
authors.lastname: Martí-Bonmatí
authors.forename: C
authors.initials: C
authors.lastname: Casillas
authors.forename: R
authors.initials: R
authors.lastname: Dosdá
mesh_terms: D000328:Adult; D002921:Cicatrix / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged