title: In vivo splicing and functional characterization of Mycobacterium leprae RecA.
abstract: The RecA proteins from Mycobacterium tuberculosis and Mycobacterium leprae contain inteins. In contrast to the M. tuberculosis RecA, the M. leprae RecA is not spliced in Escherichia coli. We demonstrate here that M. leprae RecA is functionally spliced in Mycobacterium smegmatis and produces resistance toward DNA-damaging agents and homologous recombination.
authors.affiliation: Medizinische Hochschule Hannover, Institut für Medizinische Mikrobiologie, 30625 Hannover, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Frischkorn
authors.forename: B
authors.initials: B
authors.lastname: Springer
authors.forename: E C
authors.initials: EC
authors.lastname: Böttger
authors.forename: E O
authors.initials: EO
authors.lastname: Davis
authors.forename: M J
authors.initials: MJ
authors.lastname: Colston
authors.forename: P
authors.initials: P
authors.lastname: Sander
mesh_terms: D009166:Mycobacterium leprae / Q000235:genetics / Q000378:metabolism*; D020102:Mycobacterium smegmatis / Q000235:genetics / Q000378:metabolism; D019154:Protein Splicing; D011938:Rec A Recombinases / Q000235:genetics* / Q000378:metabolism*; D011995:Recombination, Genetic
chemical_list: D011938:Rec A Recombinases