title: Presenilin-1 mutations in Alzheimer's disease.
authors.affiliation: Division of Neuropathology, Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA.
authors.forename: C
authors.initials: C
authors.lastname: Russo
authors.forename: G
authors.initials: G
authors.lastname: Schettini
authors.forename: T C
authors.initials: TC
authors.lastname: Saido
authors.forename: C
authors.initials: C
authors.lastname: Hulette
authors.forename: C
authors.initials: C
authors.lastname: Lippa
authors.forename: L
authors.initials: L
authors.lastname: Lannfelt
authors.forename: B
authors.initials: B
authors.lastname: Ghetti
authors.forename: P
authors.initials: P
authors.lastname: Gambetti
authors.forename: M
authors.initials: M
authors.lastname: Tabaton
authors.forename: J K
authors.initials: JK
authors.lastname: Teller
mesh_terms: D017668:Age of Onset; D000544:Alzheimer Disease / Q000235:genetics*; D053829:Amyloid Precursor Protein Secretases; D016564:Amyloid beta-Protein Precursor / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D016282:Aspartic Acid Endopeptidases; D001921:Brain / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics*; D009154:Mutation; D053764:Presenilin-1
chemical_list: D016564:Amyloid beta-Protein Precursor; D008565:Membrane Proteins; C508853:PSEN1 protein, human; D053764:Presenilin-1; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; D016282:Aspartic Acid Endopeptidases; C509280:BACE1 protein, human