title: [A case of left renal cell carcinoma in a young male adult with left varicocele].
abstract: A 25-year-old man presented to our hospital with the chief complaint of left-sided painless scrotal swelling. Varicocele was diagnosed and high ligation was performed. Two months later, he noticed asymptomatic gross hematuria. Transabdominal ultrasonography and abdominal computed tomographic scanning showed a left renal tumor measuring more than 10 cm in diameter. Radical nephrectomy (thoraco-abdominal approach) was performed and pathological diagnosis was granular cell carcinoma (G2, pT2, INF alpha, pNX, pMX). He then received intramuscular injections of interferon-alpha 3 million units on three days per week. The frequency of renal cell carcinoma was reported to be about 1-3% for individuals in the 20s in the recent Japanese literature, and renal cell carcinoma in a young man with left varicocele is very rare.
authors.affiliation: Department of Urology, St Luke's International Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Kontani
authors.forename: H
authors.initials: H
authors.lastname: Mizoguchi
authors.forename: F
authors.initials: F
authors.lastname: Nukui
authors.forename: J
authors.initials: J
authors.lastname: Kurokawa
authors.forename: M
authors.initials: M
authors.lastname: Nagata
authors.forename: J
authors.initials: J
authors.lastname: Fukui
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage; D003131:Combined Modality Therapy; D006801:Humans; D007273:Injections, Intramuscular; D016898:Interferon-alpha / Q000008:administration & dosage; D007680:Kidney Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008026:Ligation; D008297:Male; D009392:Nephrectomy; D014646:Varicocele / Q000150:complications* / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents; D016898:Interferon-alpha