title: Suicidal ideation in cancer patients with major depression.
abstract: BACKGROUND
  Major depression is a well-documented risk factor for suicide in cancer patients as well as in the general population. However, there are no data explaining why some cancer patients suffering from major depression have suicidal ideation whereas others with the same disorder do not.
  
  
  METHODS
  We investigated the background differences between cancer patients suffering from major depression with and without suicidal ideation by analyzing consultation data on patients referred to the Psychiatry Division, National Cancer Center Hospital, Japan.
  
  
  RESULTS
  Univariate analysis showed that poor performance status, advanced stage and severe depression were the risk factors for suicidal ideation in these depressive cancer patients. Multivariate logistic regression analysis indicated that older age and severe depression are the final significant risk factors.
  
  
  CONCLUSIONS
  These preliminary findings suggest that severe major depression may be an important indicator of suicidal ideation among cancer patients, that patients' age should be given greater attention and that closer monitoring and more intensive intervention against major depression may be needed.
authors.affiliation: Psychiatry Division, National Cancer Center Hospital, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Akechi
authors.forename: H
authors.initials: H
authors.lastname: Okamura
authors.forename: A
authors.initials: A
authors.lastname: Kugaya
authors.forename: T
authors.initials: T
authors.lastname: Nakano
authors.forename: T
authors.initials: T
authors.lastname: Nakanishi
authors.forename: N
authors.initials: N
authors.lastname: Akizuki
authors.forename: S
authors.initials: S
authors.lastname: Yamawaki
authors.forename: Y
authors.initials: Y
authors.lastname: Uchitomi
mesh_terms: D000367:Age Factors; D000368:Aged; D003866:Depressive Disorder / Q000523:psychology*; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009369:Neoplasms / Q000473:pathology / Q000523:psychology*; D012307:Risk Factors; D013406:Suicide, Attempted / Q000523:psychology*