[Useful of cerebral placental ratio in pregnancies complicated by intrauterine growth retardation and it correlation with perinatal outcome].
OBJECTIVE
The aim of this study was to asses usefulness of cerebro-placental ratio in the estimation of the intrauterine fetal well being in pregnancies complicated by intrauterine growth retardation and prediction of perinatal outcome.


METHODS
We investigated 22 pregnant women between 28th and 40th week of pregnancy with IUGR detected by ultrasound examination. 19 pregnant women between 28th and 41st week of pregnancy was control group. We measured parameters blood flow in umbilical arteries and in middle cerebral arteries in both groups. We calculated cerebro placental ratios(CPR, CPP). We divided pregnant women with IUGR int 2 groups depending on correct (CPR, CPP > 1.08) or incorrect (CPR, CPP < 1.08). In both groups we analyzed perinatal outcome.


RESULTS
In group pregnancies complicated with IUGR cerebro-placental ratios (CPR and CPP) were statistically significant lower than in control group. (for CPR p < 0.015 and for CPP p < 0.033). Sensitivity of cerebro placental ratio in screening small gestational age fetuses was 59% and specificity 89%. Sensitivity of cerebro placental ratio in predicting adverse perinatal outcome was 85% and specificity was 82%.


CONCLUSIONS
Statistically significant decrease of cerebro-placental ratios is observed in pregnancies complicated wit IUGR. Cerebro placental ratio is very useful tool for prediction of adverse perinatal outcome.
Fuchs
T
T
Katedry i Kliniki Rozrodczości i Połoznictwa AM we Wrocławiu.
Zalewski
J
J
Zimmer
M
M
Florjański
J
J
Pańczak
K
K
D001783:Blood Flow Velocity / Q000502:physiology; D001921:Brain / Q000098:blood supply*; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis*; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
Ocena współczynników mózgowo-łozyskowych w ciazach powikłanych wewnatrzmacicznym zahamowaniem wzrostu płodu i ich korelacja ze stanem pourodzeniowym noworodków.