Three novel monotetrahydrofuran annonaceous acetogenins from Annona montana.
Three new monotetrahydrofuran (mono-THF) acetogenins, anmontanins A-C (1-3) were isolated from the leaves of Annona montana. Anmontanin C (3) is the first stereochemically pure acetogenin reported to have a gamma-hydroxymethyl-gamma-lactone moiety. Two known mono-THF acetogenins, murisolin and annonacin, were isolated from the seeds of the plant. The structures of compounds 1-3 were elucidated by spectral methods and chemical derivatization.
Mootoo
B S
BS
Department of Chemistry, University of the West Indies, St. Augustine, Trinidad and Tobago. bmoot@tstt.net.tt
Ali
A
A
Khan
A
A
Reynolds
W F
WF
McLean
S
S
D005663:Furans / Q000737:chemistry / Q000302:isolation & purification*; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D018515:Plant Leaves / Q000737:chemistry; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014197:Trees / Q000737:chemistry*
D005663:Furans; D007783:Lactones; C412842:anmontanin A; C412843:anmontanin B; C412841:anmontanin C