Management of anaemia in United Kingdom renal units: a report from the UK Renal Registry.
BACKGROUND
Morbidity and mortality of patients undergoing renal replacement therapy is influenced by the adequacy of correction of renal anaemia. The Renal Association has set standards for attainment of a target haemoglobin of 10 g/dl. This study compared the management of anaemia in dialysis patients in nine renal units in the UK.


METHODS
A cross-sectional analysis was carried out on data submitted electronically to the UK Renal Registry. There were 1449 haemodialysis patients and 741 peritoneal dialysis patients in the nine renal centres analysed. Individual patient data were collected on haemoglobin, ferritin, erythropoietin prescription, and pre- and post-dialysis urea concentrations.


RESULTS
None of the centres achieved the standard of more than 80% of haemodialysis patients with a haemoglobin of greater than 10 g/dl. Three centres achieved this standard for peritoneal dialysis. There was wide variation between centres in the percentage reaching the target. Differences in ferritin, erythropoietin prescription, and dialysis doses between centres could not entirely explain the variations between centres. Females had lower haemoglobin than males despite a greater proportion being treated with erythropoietin. There was a trend of increasing haemoglobin concentration during the study period in haemodialysis but not in peritoneal dialysis patients.


CONCLUSIONS
The Renal Association standards for management of anaemia are not being met. The data allow renal centres to compare their practices with others to identify areas that might be improved. Further analysis may allow a benchmark to be determined of what it is possible to achieve by best practice.
Burton
C
C
The UK Renal Registry, Southmead Hospital, Bristol, UK.
Ansell
D
D
Taylor
H
H
Dunn
E
E
Feest
T
T
D000375:Aging / Q000097:blood; D000740:Anemia / Q000097:blood / Q000188:drug therapy*; D003430:Cross-Sectional Studies; D004921:Erythropoietin / Q000627:therapeutic use*; D005260:Female; D005293:Ferritins / Q000097:blood; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D010530:Peritoneal Dialysis; D012042:Registries; D006435:Renal Dialysis; D012727:Sex Characteristics; D013997:Time Factors; D006113:United Kingdom
D006454:Hemoglobins; D004921:Erythropoietin; D005293:Ferritins