[The mast cell reaction to a staphylococcal infection occurring against a background of immunodeficiency after cyclophosphane administration].
Materials on the study of the morphofunctional state of mast cells in mouse in experimental staphylococcal infection under the conditions of cyclophosphamide-induced immunodeficiency are presented. As revealed in this study, the infectious process developing in the presence of immunodeficiency is accompanied by the profound and prolonged suppression of the morphofunctional status of mast cells and natural immunity factors at the peak of the disease.
Krasnozhenov
E P
EP
Siberian State Medical University, Tomsk, Russia.
Fedorov
Iu V
IuV
Chubik
M P
MP
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D015550:Cell Degranulation / Q000187:drug effects; D003520:Cyclophosphamide / Q000494:pharmacology*; D004195:Disease Models, Animal; D007153:Immunologic Deficiency Syndromes / Q000139:chemically induced* / Q000276:immunology; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D008297:Male; D008407:Mast Cells / Q000187:drug effects / Q000276:immunology* / Q000502:physiology; D008643:Mesentery / Q000166:cytology; D051379:Mice; D012867:Skin / Q000166:cytology; D013203:Staphylococcal Infections / Q000276:immunology*; D013208:Staphylococcal Toxoid / Q000494:pharmacology; D013997:Time Factors
D007166:Immunosuppressive Agents; D013208:Staphylococcal Toxoid; D003520:Cyclophosphamide
Reaktsiia tuchnykh kletok na stafilokokkovuiu infektsiiu, protekaiushchuiu na fone immunodefitsita posle vvedeniia tsiklofosfana.