title: Neuro-ophthalmologic manifestations of neuroendocrine carcinoma.
abstract: The neuro-ophthalmologic findings of parasellar neuroendocrine carcinoma are reported. Two patients with parasellar neuroendocrine carcinoma had headache, ptosis, and ophthalmoplegia. In both patients, neuroimaging revealed a parasellar mass with extension into the cavernous sinus. The tumors initially were believed to be pituitary adenomas, but histopathology confirmed neuroendocrine carcinoma. Clinicians should be aware of neuroendocrine carcinoma in the differential diagnosis of sellar/parasellar lesions causing ophthalmoplegia.
authors.affiliation: Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: A G
authors.initials: AG
authors.lastname: Lee
authors.forename: A
authors.initials: A
authors.lastname: Chokshi
authors.forename: J C
authors.initials: JC
authors.lastname: Goodman
mesh_terms: D000328:Adult; D000368:Aged; D001763:Blepharoptosis / Q000175:diagnosis*; D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis*; D002426:Cavernous Sinus / Q000473:pathology*; D003937:Diagnosis, Differential; D005133:Eye Movements; D005260:Female; D006261:Headache / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009361:Neoplasm Invasiveness; D009886:Ophthalmoplegia / Q000175:diagnosis*; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis*; D014786:Vision Disorders / Q000175:diagnosis*; D014792:Visual Acuity