title: Divide and multiply: organelle partitioning in yeast.
abstract: The mechanisms ensuring accurate partitioning of yeast vacuoles and mitochondria are distinct, yet they share common elements. Both organelles move along actin filaments, and both organelles require fusion and fission to maintain normal morphology. Recent studies have revealed that while vacuolar inheritance requires a processive myosin motor, mitochondrial inheritance requires controlled actin polymerization. Distinct sets of proteins required for the fusion and fission of each organelle have also been identified.
authors.affiliation: Department of Biochemistry, University of Iowa, Iowa City, 52242, USA. natalie-catlett@uiowa.edu.
authors.forename: N L
authors.initials: NL
authors.lastname: Catlett
authors.forename: L S
authors.initials: LS
authors.lastname: Weisman
mesh_terms: D000818:Animals; D003599:Cytoskeleton / Q000502:physiology; D005656:Fungal Proteins / Q000378:metabolism; D008074:Lipoproteins / Q000378:metabolism; D008561:Membrane Fusion / Q000502:physiology; D008565:Membrane Proteins / Q000378:metabolism; D008928:Mitochondria / Q000502:physiology*; D015388:Organelles / Q000502:physiology; D012441:Saccharomyces cerevisiae / Q000378:metabolism / Q000502:physiology*; D029701:Saccharomyces cerevisiae Proteins; D014617:Vacuoles / Q000502:physiology; D033921:Vesicular Transport Proteins
chemical_list: D005656:Fungal Proteins; D008074:Lipoproteins; D008565:Membrane Proteins; D029701:Saccharomyces cerevisiae Proteins; C111373:VAC8 protein, S cerevisiae; D033921:Vesicular Transport Proteins