title: Fluoride profiles in dental plaque in vivo formed on fluoride pre-treated human enamel.
abstract: Using a novel device capable of generating plaque in vivo on a natural enamel substrate, it has been possible to determine fluoride profiles from the saliva-plaque interface towards the enamel surface. Fluoride profiles in dental plaques tended to fall from the saliva-plaque interface towards the enamel. The device also offered the possibility of examining fluoride distributions after pre-treatment of the enamel with fluoride in vitro. Fluoride profiles were determined in plaque generated in vivo on enamel surfaces, which had been previously treated with a 900-ppm fluoride solution. The results showed the previously reported fall from the plaque surface, but in addition, a further rise towards the enamel surface was seen. The data imply that enamel loaded with fluoride can release some of this fluoride back into the plaque and may act as a fluoride reservoir.
authors.affiliation: Department of Preventive Dentistry and Dental Public Health, School of Dentistry, Aichi-Gakuin University, Nagoya, Japan. arai@dpc.aichi-gakuin.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Arai
authors.forename: K
authors.initials: K
authors.lastname: Kato
authors.forename: H
authors.initials: H
authors.lastname: Nakagaki
authors.forename: A
authors.initials: A
authors.lastname: Toyama
authors.forename: N
authors.initials: N
authors.lastname: Nagai
authors.forename: T
authors.initials: T
authors.lastname: Noguchi
authors.forename: J
authors.initials: J
authors.lastname: Kirkham
authors.forename: C
authors.initials: C
authors.lastname: Robinson
authors.forename: T T
authors.initials: TT
authors.lastname: Thuy
authors.forename: N T
authors.initials: NT
authors.lastname: Ha
mesh_terms: D002118:Calcium / Q000032:analysis; D002327:Cariostatic Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics; D003743:Dental Enamel / Q000378:metabolism*; D003773:Dental Plaque / Q000737:chemistry / Q000188:drug therapy*; D005459:Fluorides / Q000008:administration & dosage* / Q000493:pharmacokinetics; D006801:Humans; D010710:Phosphates / Q000032:analysis; D014089:Tooth Remineralization / Q000379:methods*
chemical_list: D002327:Cariostatic Agents; D010710:Phosphates; D005459:Fluorides; D002118:Calcium