title: [Molecular genetic analysis of polymorphism of the HindII and (CA)-repeat of the factor VIII gene loci in people of the Volgo-Ural region].
abstract: Molecular genetic analysis of polymorphism of the factor VIII gene at loci HindIII (intron 19) and (CA)-repeats (intron 13) was performed in seven ethnic groups of the Volga-Ural region (Bashkirs, Tatars, Chuvashes, Maris, Mordovians, Udmurts, and Komis). The allelic frequency of the HindIII locus was shown to be similar in these ethnic groups. The ethnic groups were more heterogeneous with regard to the genotype and allele frequencies of (CA)-repeats, which indicates that this polymorphic system can be used to characterize the genetic structure of the Volga-Ural human populations.
authors.affiliation: Institute of Biochemistry and Genetics, Bashkir Scientific Center, Russian Academy of Sciences, Bashkortosan, Russia.
authors.forename: Z M
authors.initials: ZM
authors.lastname: Sultanaeva
authors.forename: T V
authors.initials: TV
authors.lastname: Viktorova
authors.forename: M V
authors.initials: MV
authors.lastname: Aseev
authors.forename: V S
authors.initials: VS
authors.lastname: Baranov
authors.forename: E K
authors.initials: EK
authors.lastname: Khusnutdinova
mesh_terms: D000483:Alleles; D015247:Deoxyribonuclease HindIII / Q000378:metabolism; D018900:Dinucleotide Repeats; D005006:Ethnicity; D005169:Factor VIII / Q000235:genetics*; D005787:Gene Frequency; D006801:Humans; D007438:Introns; D011110:Polymorphism, Genetic; D012426:Russia
chemical_list: D005169:Factor VIII; D015247:Deoxyribonuclease HindIII
vernacular_title: Molekuliarno-geneticheskiĭ analiz polimorfizma lokusov HindIII i (CA)-povtorov gena gaktora VIII u narodov volgo-ural'skogo regiona.