Primary cutaneous CD30-positive large cell lymphoma.
Primary cutaneous CD30-positive large cell lymphoma is a recently described entity, recognized by immunohistochemical criteria. Spontaneous regression may occur and although relapses are frequent, most patients have a favourable prognosis. We describe a 83-year-old woman with a large ulcerated tumour on her right forearm, with 2 months evolution. Histological and immunohistochemical examination revealed a CD30-positive large cell lymphoma. Systemic involvement was not detected. The tumour regressed spontaneously. Cutaneous relapses occurred one year later, all with spontaneous regression. After a 2-year follow-up period, the patient is well, without concurrent extracutaneous disease. This case is in keeping with other reports of spontaneous regression and favourable outcome of this type of cutaneous lymphoma.
Freitas
I C
IC
Department of Dermatology, Curry Cabral Hospital, Lisbon, Portugal. isabel.cristina.freitas@ip.pt
Vieira
R
R
Afonso
A
A
Pacheco
A
A
Nunes
P
P
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D017730:Ki-1 Antigen / Q000032:analysis*; D017728:Lymphoma, Large-Cell, Anaplastic / Q000737:chemistry*; D012878:Skin Neoplasms / Q000737:chemistry*
D017730:Ki-1 Antigen