Temporal lobectomy outcome in older versus younger adults.
A total of 340 patients age 50 years and older were compared with 30 patients younger than 50 years, all of whom had anterior temporal lobectomy for refractory epilepsy. Seizure outcome, neuropsychological test scores, and change in driving status were analyzed. Age and duration of epilepsy were related independently to outcome, but laterality of interictal sharp waves (an early epilepsy risk factor) and presence of tumor were not. Sixteen patients (52%) in the older group and 257 patients (75.6%) in the younger group (p < 0.008) were seizure free. Postoperative neuropsychological outcome and driving status were similar in older and younger patients.
Sirven
J I
JI
Department of Neurology, Mayo Clinic, Scottsdale, AZ 85259, USA.
Malamut
B L
BL
O'Connor
M J
MJ
Sperling
M R
MR
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D016009:Chi-Square Distribution; D016002:Discriminant Analysis; D004828:Epilepsies, Partial / Q000523:psychology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012189:Retrospective Studies; D013702:Temporal Lobe / Q000601:surgery*; D016896:Treatment Outcome