[Local cerebral blood flow, cortical impedance, cerebral intravascular kinin production during forebrain ischemia and reperfusion in rats].
In the rat model of forebrain ischemia with subsequent reperfusion, an obvious formation of intravascular kinin (IVKF) occurred. The IVKF preceded and coincided in time with the maximum hyperemia and a vasogenic oedema. Local cerebral blood flow (LCBF) increased up to about 187%, at that. In three groups of experimental rats, a correlation was revealed among the ischemia obviousness, IVKF, and development of the brain oedema.
Semeniutin
V B
VB
Polenov Russian Research Neurosurgical Institute, St. Petersburg, Russia.
Zubkov
Iu N
IuN
Lomova
I P
IP
Eremeev
V S
VS
D000818:Animals; D001929:Brain Edema / Q000209:etiology; D002545:Brain Ischemia / Q000097:blood / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000098:blood supply / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D017097:Electric Impedance; D007705:Kinins / Q000096:biosynthesis* / Q000097:blood; D008297:Male; D016548:Prosencephalon / Q000098:blood supply*; D051381:Rats; D017208:Rats, Wistar; D015424:Reperfusion
D007705:Kinins
Lokal'nyĭ mozgovoĭ krovotok, kortikal'nyĭ impedans, tserebral'noe vnutrisosudistoe kininoobrazovanie pri perednemozgovoĭ ishemii i reperfuzii u krys.