title: First permanent molar: first indicator of dental caries activity in initial mixed dentition.
abstract: The objective of the present study was to investigate among children in the initial mixed dentition phase the presence of clinical signs that might eventually function as more sensitive indicators of the development of caries disease, denoted here as caries activity. On this basis, we investigated the relationship between salivary levels of mutans streptococci (MS) and decayed, missing and filled permanent and deciduous tooth surfaces (DMFS and dmfs) using microbiological, clinical and radiographic examinations in 81 schoolchildren aged 7-8 years. Whereas dmfs did not present a positive correlation, DMFS was significantly correlated with salivary MS levels. The first permanent molars of the schoolchildren studied comprised 87.3% of the affected surfaces recorded in the DMFS, suggesting that the development of new lesions was preferentially located on the surfaces of the first permanent molars. These results permit us to conclude that the first permanent molars function as first indicators of dental caries activity in the schoolchildren examined.
authors.affiliation: Departamento de Odontopediatria e Ortodontia, Faculdade de Odontologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil. fanoron@gold.com.br
authors.forename: J C
authors.initials: JC
authors.lastname: Noronha
authors.forename: M de L
authors.initials: Mde L
authors.lastname: Massara
authors.forename: B Q
authors.initials: BQ
authors.lastname: Souki
authors.forename: A P
authors.initials: AP
authors.lastname: Nogueira
mesh_terms: D002648:Child; D004245:DMF Index; D003731:Dental Caries / Q000175:diagnosis* / Q000382:microbiology; D003818:Dentition, Mixed; D006801:Humans; D008963:Molar / Q000473:pathology; D012463:Saliva / Q000382:microbiology; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D013295:Streptococcus mutans / Q000302:isolation & purification