[Interaction of ATP17 gene with SUP45 and SUP35 genes in Saccharomyces cerevisiae yeast].
Genes SUP35 and SUP45 have been identified in the saccharomycete yeast as genes controlling termination of translation in cytoplasmic ribosomes. However, many facts indicate that the control of translation termination is not the only function of these genes. This work is devoted to studying one of the pleiotropic effects of sup35 and sup45 mutations, a respiratory deficiency. The compensation for this deficiency in mutants for either gene can occur due to a mutation in the ATP17 gene encoding the f-subunit of mitochondrial F1F0 ATP synthase. It is assumed that the observed interaction can be related to the system of co-translational protein import into mitochondria.
Shumov
N N
NN
Department of Genetics and Selection, St. Petersburg State University, Russia.
Volkov
K V
KV
Mironova
L N
LN
D001483:Base Sequence; D003001:Cloning, Molecular; D017931:DNA Primers; D005656:Fungal Proteins / Q000235:genetics*; D005800:Genes, Fungal; D025261:Mitochondrial Proton-Translocating ATPases; D009154:Mutation; D010454:Peptide Termination Factors; D011328:Prions; D006180:Proton-Translocating ATPases / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins
D017931:DNA Primers; D005656:Fungal Proteins; D010454:Peptide Termination Factors; D011328:Prions; C068068:SUP35 protein, S cerevisiae; C080775:SUP45 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; C108166:ATP17 protein, S cerevisiae; D025261:Mitochondrial Proton-Translocating ATPases; D006180:Proton-Translocating ATPases
Vzaimodeĭstvie gena ATP17 s genami SUP45 i SUP35 u drozhzheĭ Saccharomyces cerevisiae.