[The revaccination against diphtheria and tetanus with adsorbed DT-m anatoxin of children having solid tumors in their case histories].
Data on the safety and effect of the vaccination of children with solid tumors are presented. As revealed in this study, the injection of adsorbed DT-m toxoid with reduced antigen content at the period of remission does not induce the relapse of the disease and leads to the production of specific antitoxic antibodies on the protective level. The study has shown that complex antitumor treatment does not essentially affect the formation of specific immune response, though prolonged changes in cell-mediated immunity can be observed.
Karpocheva
S V
SV
Mechnikov Research Institute for Vaccines and Sera, Research Institute of Child Oncology and Hematology, Moscow, Russia.
Kostinov
M P
MP
Zaeva
G E
GE
Gurvich
E B
EB
Zaĭtseva
L A
LA
Gavrilova
G L
GL
Korotkova
O V
OV
Kuznetsova
A V
AV
D000907:Antibodies, Bacterial / Q000097:blood; D000918:Antibody Specificity; D002648:Child; D003017:Clostridium tetani / Q000276:immunology; D003353:Corynebacterium diphtheriae / Q000276:immunology; D004165:Diphtheria / Q000517:prevention & control*; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007117:Immunization, Secondary / Q000706:statistics & numerical data; D007136:Immunoglobulins / Q000097:blood; D009369:Neoplasms / Q000276:immunology*; D013742:Tetanus / Q000517:prevention & control*; D013997:Time Factors
D000907:Antibodies, Bacterial; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D007136:Immunoglobulins
Revaktsinatsiia protiv difterii i stolbniaka ADS-m anatoksinom deteĭ, imeiushchikh v anamneze solidnye opukholi.