A high-density single-nucleotide polymorphism map of Xq25-q28.
A high-density single-nucleotide polymorphism (SNP) map was developed for Xq25-q28 using a targeted approach to SNP discovery. This high-density map includes 217 new SNP markers, and 117 are informative in the CEPH parent population with >20% minor allele frequency. The average distance between SNP markers is 100 kb in the targeted regions. This is the densest genetic map of Xq25-q28 to date. The SNP markers are presented in order by their distance in megabases along the X chromosome, and the markers from the current genetic map are placed using the same scale to produce an integrated map of the region.
Taillon-Miller
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Division of Dermatology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Kwok
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D001483:Base Sequence; D005819:Genetic Markers; D006801:Humans; D008969:Molecular Sequence Data; D020161:Physical Chromosome Mapping; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D017422:Sequence Analysis, DNA; D016324:Sequence Tagged Sites; D014960:X Chromosome / Q000235:genetics*
D005819:Genetic Markers