title: Frequency, clinical features and risk factors of lacunar infarction (data from a stroke registry in South India).
abstract: Analysis of 893 patients of ischaemic stroke in the stroke registry of Nizam's institute of Medical Sciences, Hyderabad is presented. 16% of them had lacunar infarction. The mean age at presentation was 56.9 years and male to female ratio was 3.5:1. The common risk factors included hypertension(62%),diabetes(38%) and smoking(28%). Six percent had an underlying cardiac source of embolism and none had significant (>50%) extracranial carotid atherosclerosis. In 22% of patients, no obvious risk factors could be identified. The frequency of risk factors was similar in patients with lacunar and non- lacunar infarctions. However, patients with lacunar infarction had higher frequency of diabetes and absence of significant (>50%) extracranial carotid artery disease. Pure motor hemiparesis was the presenting syndrome in 45% patients. Ataxic hemiparesis and sensorimotor stroke accounted for 18% each and dysarthria-clumsy hand syndrome for 14%. This study suggests that the frequency, risk factors and clinical profile of lacunar infarction in our stroke registry is similar to most of the western stroke registries.
authors.affiliation: Department of Neurology, Nizam's Institute of Medical Sciences, Panjagutta, Hyderabad, 500082, India.
authors.forename: S
authors.initials: S
authors.lastname: Kaul
authors.forename: P
authors.initials: P
authors.lastname: Venketswamy
authors.forename: A K
authors.initials: AK
authors.lastname: Meena
authors.forename: R
authors.initials: R
authors.lastname: Sahay
authors.forename: J M
authors.initials: JM
authors.lastname: Murthy
mesh_terms: D000368:Aged; D002544:Cerebral Infarction / Q000453:epidemiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D012042:Registries; D012307:Risk Factors