title: Two functional magnetic resonance imaging f(MRI) tasks that may replace the gold standard, Wada testing, for language lateralization while giving additional localization information.
abstract: Two tasks were used to lateralize and localize language functions noninvasively, using functional magnetic resonance (fMRI BOLD sequences). fMRI images produced during comprehension of the gist of a tale derived from an ordered series of inferential questions were used to lateralize and locate the center of and margins within language dominant hemisphere near posterior temporal-parietal-occipital (TPO) cortical area(s), e.g., Wernicke's. A silent noun-generating task was used to lateralize and localize naming functions within and along superior temporal gyrus (STG) and/or the basal temporal language area (BTLA) in fusiform gyrus. Used within a series of tasks, their purpose was to investigate the reliability and validity of replacing the invasive gold standard for language lateralization, Wada test, with a noninvasive test, BOLD fMRI.
authors.affiliation: Memory Testing Corporation, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Brockway
mesh_terms: D000293:Adolescent; D000328:Adult; D000654:Amobarbital; D001921:Brain / Q000033:anatomy & histology / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D018757:GABA Modulators; D006801:Humans; D007802:Language; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009778:Occipital Lobe / Q000033:anatomy & histology / Q000502:physiology; D010296:Parietal Lobe / Q000033:anatomy & histology / Q000502:physiology; D015203:Reproducibility of Results; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000502:physiology
chemical_list: D018757:GABA Modulators; D000654:Amobarbital