Expression patterns of follistatin and two follistatin-related proteins during mouse development.
We compared the expression patterns of follistatin and two follistatin-related proteins (FRP and m7365) during early mouse development. m7365 is expressed continuously during preimplantation development, in contrast to FRP and follistatin. At early postimplantation stages, follistatin and 7365 are expressed from E6.0, while FRP is detected from E7.5 onwards. Although there is some overlap between the expression of these genes in the primitive streak and somites, their overall expression patterns are distinct.
De Groot
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E
Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht.
Feijen
A
A
Eib
D
D
Zwijsen
A
A
Sugino
H
H
Martens
G
G
Van Den Eijnden-Van Raaij
A J
AJ
D000818:Animals; D001755:Blastocyst / Q000378:metabolism*; D018076:DNA, Complementary / Q000378:metabolism; D004622:Embryo, Mammalian / Q000378:metabolism*; D038681:Follistatin; D038702:Follistatin-Related Proteins; D006023:Glycoproteins / Q000096:biosynthesis*; D017403:In Situ Hybridization; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013997:Time Factors; D014018:Tissue Distribution
D018076:DNA, Complementary; D038681:Follistatin; D038702:Follistatin-Related Proteins; D006023:Glycoproteins