[The role of glycolysis in the protective effect of amtizol during acute hypoxia].
In rats, protective effect of amtizol was found to depend on the rate of carbohydrate substrate in the organism as well as on the glycolysis activity. Amtizol was able to activate utilising of carbohydrates in a glycolytic way in satisfied rats with a blockade of glycolysis by monoiodacetate, whereas glyconeogenesis was activated in starving rats.
Smirnov
A V
AV
Military Medical Academy, St. Petersburg, Russia.
Zarubina
I V
IV
Krivoruchko
B I
BI
D000208:Acute Disease; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D050260:Carbohydrate Metabolism; D005508:Food Deprivation; D006019:Glycolysis; D000860:Hypoxia / Q000378:metabolism* / Q000401:mortality / Q000517:prevention & control*; D008297:Male; D051381:Rats; D013830:Thiadiazoles / Q000494:pharmacology*
D000975:Antioxidants; D013830:Thiadiazoles; C044365:amtizol
Rol' glikoliza v realizatsii zashchitnykh éffektov amtizola pri ostroĭ gipoksii.