Indium-111 capromab pendetide (ProstaScint) uptake in neurofibromatosis.
We report on the demonstration of nonspecific accumulation of indium-111 capromab pendetide (ProstaScint) in neurofibromas in a patient with a rising prostate-specific antigen level after prostatectomy. Although the immunoconjugate is targeted to a specific membrane antigen present in human prostate carcinoma, nonspecific uptake can occur in other entities. Indium-111 capromab pendetide scintigraphy is a valuable diagnostic tool that should always be interpreted within the context of the clinical history and the laboratory and radiologic findings to avoid misinterpretation.
Khan
A
A
Department of Radiology, Section of Nuclear Medicine, Hospital of Saint Raphael, New Haven, Connecticut 06511, USA.
Caride
V J
VJ
D000911:Antibodies, Monoclonal / Q000493:pharmacokinetics*; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D008875:Middle Aged; D017253:Neurofibromatoses / Q000000981:diagnostic imaging / Q000378:metabolism*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism; D011877:Radionuclide Imaging
D000911:Antibodies, Monoclonal; D007205:Indium Radioisotopes; C101315:Capromab Pendetide