title: Pregnancy outcome after previous stillbirth resulting from causes other than maternal conditions and fetal abnormalities.
abstract: BACKGROUND
  An adequate fetomaternal circulatory system may be compromised by a variety of disturbances leading to stillbirth. The purpose of this study was to assess subsequent pregnancy outcome in women with a history of stillbirth as a result of causes other than maternal conditions and fetal abnormalities.
  
  
  METHODS
  Ninety-two deliveries after stillbirth were identified among 11,910 deliveries of parous women recorded in the birth registry at Kuopio, Finland. Using logistic regression, pregnancy outcome measures were compared with those of a parous healthy obstetric population (n = 11,818).
  
  
  RESULTS
  Women with a history of stillbirth as a result of causes other than maternal conditions and fetal abnormalities were older than their unaffected controls (32.4 yr vs 30.3 yr). Stillbirth in an earlier pregnancy was associated with a significantly higher (p < 0.001) frequency of placental abruption in subsequent pregnancy (5.4% vs 0.7%). A history of stillbirth was predictive of preterm delivery (OR = 2.25) and low-birthweight infants (OR = 2.70). No recurrence was reported.
  
  
  CONCLUSIONS
  Pregnancy with a history of stillbirth as a result of causes other than maternal conditions and fetal abnormalities is a moderate risk state, with prematurity and low-birthweight rates somewhat higher than those in the general population. The overall probability of a favorable outcome is good. These findings may be useful in counseling pregnant women with a history of stillbirth.
authors.affiliation: Department of Obstetrics and Gynecology, Kuopio University Hospital, Finland.
authors.forename: S
authors.initials: S
authors.lastname: Heinonen
authors.forename: P
authors.initials: P
authors.lastname: Kirkinen
mesh_terms: D000293:Adolescent; D000328:Adult; D001719:Birth Certificates; D002423:Cause of Death; D000013:Congenital Abnormalities; D003430:Cross-Sectional Studies; D005260:Female; D005313:Fetal Death / Q000209:etiology*; D005387:Finland / Q000453:epidemiology; D006801:Humans; D016015:Logistic Models; D007752:Obstetric Labor, Premature / Q000209:etiology; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D012008:Recurrence; D012042:Registries; D012307:Risk Factors