title: [Effect of composition of reagents for activated partial thromboplastin time on their sensitivity during analysis of blood coagulation factors].
abstract: Brain cephaline-based reagents for evaluating activated partial thromboplastin time (APTT) and soybean phosphatides with ellagic acid complex activator with intermediate metal ions have been studied. The sensitivity of these reagents to internal clotting factors (VIII and IX) and heparin is determined by phospholipid nature and type of metal. The results help obtain highly active and sensitive APTT reagents.
authors.forename: A L
authors.initials: AL
authors.lastname: Berkovskiĭ
authors.forename: S A
authors.initials: SA
authors.lastname: Vasil'ev
authors.forename: E V
authors.initials: EV
authors.lastname: Sergeeva
authors.forename: A A
authors.initials: AA
authors.lastname: Kozlov
mesh_terms: D005164:Factor IX / Q000032:analysis*; D005169:Factor VIII / Q000032:analysis*; D006801:Humans; D007202:Indicators and Reagents; D010314:Partial Thromboplastin Time; D012015:Reference Standards; D012680:Sensitivity and Specificity
chemical_list: D007202:Indicators and Reagents; D005169:Factor VIII; D005164:Factor IX
vernacular_title: Vliianie sostava AChTV-reagentov na ikh chuvstvitel'nost' pri opredelenii aktivnosti faktorov svertyvaniia.