title: Vascular radiation therapy to reduce coronary artery restenosis.
abstract: Restenosis of the dilated segment following percutaneous transluminal angioplasty is a commonly occurring problem. Several techniques such as pharmacologic agents, directional atherectomy, and endovascular stenting have been attempted with little success. This article gives an outline on the scope of the problem of restenosis, its pathophysiology, attempted treatments, and the promise of coronary vascular radiation therapy.
authors.affiliation: Department of Radiation Oncology, Brown University School of Medicine, Rhode Island Hospital, Providence, RI 02903, USA.
authors.forename: P B
authors.initials: PB
authors.lastname: Chougule
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D017225:Atherectomy, Coronary; D001918:Brachytherapy / Q000379:methods*; D003327:Coronary Disease / Q000503:physiopathology / Q000532:radiotherapy* / Q000628:therapy; D003331:Coronary Vessels / Q000503:physiopathology / Q000528:radiation effects*; D006801:Humans; D019275:Radiopharmaceuticals / Q000008:administration & dosage / Q000627:therapeutic use; D012008:Recurrence; D015607:Stents; D016896:Treatment Outcome; D017539:Tunica Intima / Q000503:physiopathology
chemical_list: D019275:Radiopharmaceuticals