Interleaved spiral cine coronary artery velocity mapping.
Navigator-echo controlled interleaved spiral cine coronary-artery velocity maps were acquired in eight free-breathing volunteers. Good quality data were achieved in all subjects with phasic flow being clearly demonstrated. The improved efficiency of spiral k-space coverage compared to that of more conventional spin-warp techniques resulted in a mean scan time for 256 x 256 pixel-matrix studies of 94 sec (range 69 - 123 sec, SD = 20 sec), the navigator acceptance rate being typically 40-45%. Repeat scans in five subjects showed a high degree of reproducibility, with no significant differences occurring in the peak velocities (14.6+/-1.4 cm/sec vs. 14.5+/-1.5 cm/sec, P = ns) nor in the mean velocities measured over all cine phases (8.3+/-2.1 cm/sec vs. 8.7+/-1.6 cm/sec, P = ns). The potential benefits of using this sequence for assessing coronary blood flow and flow reserve are discussed. Magn Reson Med 43:787-792, 2000.
Keegan
J
J
Magnetic Resonance Unit, Royal Brompton and Harefield NHS Hospital Trust, London, UK. j.keegan@rbh.nthames.nhs.uk
Gatehouse
P
P
Yang
G Z
GZ
Firmin
D
D
D001783:Blood Flow Velocity; D003326:Coronary Circulation / Q000502:physiology*; D003327:Coronary Disease / Q000503:physiopathology; D003331:Coronary Vessels / Q000502:physiology*; D006801:Humans; D018810:Magnetic Resonance Angiography; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D012016:Reference Values; D012680:Sensitivity and Specificity