[The osteoplastic efficacy of different forms of hydroxyapatite based on experimental morphological study data].
Time course of healing of induced defects in the femoral bone filled with various forms of hydroxyapatite (HA) was studied in experimental rats on days 30, 60, and 90 after inflicting the defect. HA granulate exerted the best effect on bone repair. In experiments with HA granulate, bone regenerate replaced up to one half of the area of defect by day 90. After insertion of a mixture of granulate and HA powder in bone defects the newly formed bone occupied a little more than one-third of the defect area. In experiments with HA powder suspension the size of bone defect by day 90 was the same as after healing under a blood clot.
Grigor'ian
A S
AS
Volozhin
A I
AI
Agapov
V S
VS
Belozerov
M N
MN
Drobyshev
A Iu
AIu
D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects; D018786:Bone Substitutes / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D017886:Durapatite / Q000627:therapeutic use*; D005269:Femur / Q000187:drug effects / Q000473:pathology / Q000601:surgery; D051381:Rats; D013997:Time Factors
D018786:Bone Substitutes; D017886:Durapatite
Osteoplasticheskaia éffektivnost' razlichnykh form gidroksiapatita po dannym éksperimental'no-morfologicheskogo issledovaniia.