Immunocytochemical evidence for the coexistence of catecholestrogen and catechol-O-methyltransferase in the rat parotid gland.
Catechol-O-methyltransferase (COMT) (EC 2.1.1.6) and catecholestrogen were localized in the parotid gland of the rat by immunocytochemical methods. Specific immunoreactive deposits for COMT and catecholestrogen were found in the cytoplasm of duct cells, but only those for COMT in myo-epithelial cells. The pattern of localization of COMT and catecholestrogen in the parotid gland suggests a functional relationship between COMT and catecholestrogen.
Inoue
K
K
Department of Oral Anatomy, School of Dentistry, Okayama University, Japan.
Yoshizawa
I
I
Creveling
C R
CR
D000818:Animals; D002394:Catechol O-Methyltransferase / Q000032:analysis*; D003593:Cytoplasm / Q000201:enzymology / Q000648:ultrastructure; D004847:Epithelial Cells / Q000166:cytology / Q000201:enzymology; D002393:Estrogens, Catechol / Q000032:analysis*; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D010306:Parotid Gland / Q000166:cytology* / Q000201:enzymology / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar; D018987:Salivary Ducts / Q000201:enzymology / Q000648:ultrastructure
D002393:Estrogens, Catechol; D002394:Catechol O-Methyltransferase