How cystic fibrosis affects pancreatic ductal bicarbonate secretion.
Pancreatic bicarbonate secretion is impaired in patients with cystic fibrosis. This article reviews recent advances in bicarbonate dependent transporters in pancreatic duct cells and discusses their regulation in cystic fibrosis.
Soleimani
M
M
Department of Medicine, University of Cincinnati, Ohio, USA. Manoocher.soleimani@uc.edu
Ulrich
C D
CD
D000136:Acid-Base Equilibrium / Q000235:genetics / Q000502:physiology*; D000818:Animals; D001639:Bicarbonates / Q000378:metabolism*; D003550:Cystic Fibrosis / Q000235:genetics / Q000503:physiopathology*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics / Q000502:physiology; D010183:Pancreatic Ducts / Q000378:metabolism*; D012633:Secretin / Q000502:physiology
D001639:Bicarbonates; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D012633:Secretin