High-yield formation of giant bis(bicyclic) and crypt-tris(bicyclic) molecules under normal reaction conditions
We report the unexpected result of the reaction of 1, 3-bis[(9-anthrylmethoxy)methyl]benzene (1a) or 1,3, 5-tris[(9-anthrylmethoxy)methyl]benzene (1b) with tris(2-maleimidoethyl)amine (2) in homogeneous solution leading to giant bis(bicyclic) and crypt-tris(bicyclic) molecules. The anticipated, intractable solids are obtained in a condensed state reaction using an oscillating mill.
Dam
MA
Department of Chemistry and Biochemistry, University of California at Los Angeles, 405 Hilgard Avenue, Los Angeles, California 90095, USA.
Weitz
A
Helgeson
R
Ma
B
Wudl
F