Antioxidants and cancer, part 3: quercetin.
Quercetin is a flavonoid molecule ubiquitous in nature. A number of its actions make it a potential anti-cancer agent, including cell cycle regulation, interaction with type II estrogen binding sites, and tyrosine kinase inhibition. Quercetin appears to be associated with little toxicity when administered orally or intravenously. Much in vitro and some preliminary animal and human data indicate quercetin inhibits tumor growth. More research is needed to elucidate the absorption of oral doses and the magnitude of the anti-cancer effect.
Lamson
D W
DW
Bastyr University - Kenmore, WA, USA. davisl@seanet.com
Brignall
M S
MS
D000042:Absorption; D000975:Antioxidants / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D001682:Biological Availability; D015536:Down-Regulation; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D011794:Quercetin / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*
D000975:Antioxidants; D011794:Quercetin