Co-localization of cart peptide immunoreactivity and nitric oxide synthase activity in rat hypothalamus.
Because of the reported presence of both CART peptide and NOS activity in the same hypothalamic nuclei, their colocalization was examined. Eighteen percent of the neurons in the supraoptic nuclei, and 16% of the neurons in the paraventricular nucleus contained both CART immunoreactivity and NOS activity. Many other neurons in these regions stained for only one marker although they were often close by. Thus, CART peptides and NO may interact in these regions.
Koylu
E O
EO
Ege University, Center for Brain Research, Basic Neuroscience Unit of TUBITAK, Bornova, Izmir, Turkey.
Weruaga
E
E
Balkan
B
B
Alonso
J R
JR
Kuhar
M J
MJ
Pogun
S
S
D000818:Animals; D004435:Eating / Q000502:physiology*; D007031:Hypothalamus / Q000166:cytology / Q000378:metabolism*; D008297:Male; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D019001:Nitric Oxide Synthase / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D000098882:Cocaine- and Amphetamine-Regulated Transcript Protein
D009419:Nerve Tissue Proteins; D000098882:Cocaine- and Amphetamine-Regulated Transcript Protein; D019001:Nitric Oxide Synthase