title: Picornavirus RNA translation: roles for cellular proteins.
abstract: Picornavirus RNA is translated within cells even when cellular cap-dependent protein synthesis is blocked. The efficiency of recognition of the viral RNA by the translational apparatus can determine viral tropism. The roles of cellular translation-initiation factors and other RNA-binding proteins in viral RNA-mediated protein synthesis are discussed.
authors.affiliation: BBSRC Institute for Animal Health, Pirbright, Woking, Surrey, UK GU24 0NF. graham.belsham@bbsrc.ac.uk
authors.forename: G J
authors.initials: GJ
authors.lastname: Belsham
authors.forename: N
authors.initials: N
authors.lastname: Sonenberg
mesh_terms: D020121:5' Untranslated Regions / Q000235:genetics; D002478:Cells, Cultured; D006801:Humans; D010849:Picornaviridae / Q000235:genetics* / Q000378:metabolism; D014176:Protein Biosynthesis; D011506:Proteins / Q000378:metabolism*; D012367:RNA, Viral / Q000378:metabolism*; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism
chemical_list: D020121:5' Untranslated Regions; D011506:Proteins; D012367:RNA, Viral; D014764:Viral Proteins