title: Characterization of chromosomal breakpoints in an ALL patient using cross-species color banding.
abstract: Cross-species color-banded karyotype (Rx-FISH) results were compared with those of conventional G-banded metaphases from the same sample. Breakpoints and karyotype were confirmed as 46,XX,t(8;22)(q24;q11), der(9)t(1;9)(q21;p13) through the novel technology of cross-species color banding in an acute leukemic patient (ALL, L3); the karyotype was 46,XX,t(8;22)(q24;q11),der(9)t(1;9)(q25;p24) by conventional G-banding.
authors.affiliation: Department of Clinical Pathology, Chungnam National University Hospital, Taejon, South Korea.
authors.forename: S H
authors.initials: SH
authors.lastname: Koo
authors.forename: K C
authors.initials: KC
authors.lastname: Kwon
authors.forename: J W
authors.initials: JW
authors.lastname: Park
authors.forename: Y E
authors.initials: YE
authors.lastname: Lee
authors.forename: J W
authors.initials: JW
authors.lastname: Kim
mesh_terms: D000328:Adult; D002871:Chromosome Banding / Q000379:methods*; D002878:Chromosomes, Human, Pair 1 / Q000648:ultrastructure; D002892:Chromosomes, Human, Pair 22 / Q000648:ultrastructure; D002898:Chromosomes, Human, Pair 8 / Q000648:ultrastructure; D002899:Chromosomes, Human, Pair 9 / Q000648:ultrastructure; D017809:Fatal Outcome; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic