title: [The ecological determinacy of the intraspecies diversity of pathogenic bacteria].
abstract: The review deals with some theoretical and applied problems of the intraspecific diversity of pathogenic microorganisms. Special attention is given to the role of ecological factors in the formation of the phenotypic polymorphism of bacteria. The possibility of using the methods of mathematical analysis for the evaluation of the influence of the environment (ecotopes) on individual phenotypic characteristics of bacteria and their complex (bioprofile) is shown. The proposition on the bioprofile of microorganisms as a criterion of their ecological (ecotopic) marking is substantiated. The examples of using the data of the ecological marking of pathogenic bacteria in clinical epidemiology and ecological practice are presented.
authors.affiliation: Research Institute of Cellular and Intracellular Symbiosis, Orenburg, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Bukharin
authors.forename: V A
authors.initials: VA
authors.lastname: Gritsenko
mesh_terms: D001419:Bacteria / Q000145:classification / Q000235:genetics / Q000472:pathogenicity*; D017753:Ecosystem; D014644:Genetic Variation; D006801:Humans; D010641:Phenotype; D011110:Polymorphism, Genetic; D013045:Species Specificity
vernacular_title: Ekologicheskaia determinirovannost' vnutrividovogo raznoobraziia patogennykh bakteriĭ.