title: [Acute hepatitis B in anti-HCV-positive patients].
abstract: Seventy-six anti-HCV-positive patients with acute hepatitis B were observed. HBsAg, anti-HBc IgM, and anti-HCV were detected in the sera of all patients. During the acute phase of illness, HBV DNA was present in the sera of 90.8% patients, but not HCV RNA. The clinical picture of acute hepatitis B in anti-HCV-positive patients corresponded to HBV monoinfection with prolonged intoxication and a more benign biochemical course. Out of 10 patients observed during 2 years chronic mixed HBV/HCV hepatitis was diagnosed in 1 patient, in 8 patients only HCV infection was diagnosed, and in 6 cases HCV RNA was detected. Virus interference may be responsible for successive alternative dominant replication of HBV and HCV.
authors.forename: T V
authors.initials: TV
authors.lastname: Shkurko
authors.forename: S G
authors.initials: SG
authors.lastname: Cheshik
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D016174:Hepacivirus / Q000235:genetics / Q000276:immunology* / Q000502:physiology; D006509:Hepatitis B / Q000150:complications* / Q000821:virology; D006515:Hepatitis B virus / Q000235:genetics / Q000502:physiology; D006526:Hepatitis C / Q000150:complications* / Q000821:virology; D006801:Humans; D012367:RNA, Viral / Q000097:blood; D014779:Virus Replication
chemical_list: D000914:Antibodies, Viral; D012367:RNA, Viral
vernacular_title: Ostryĭ gepatit B u anti-HCV-pozitivnykh patsientov.