The modulation of host cell apoptosis by intracellular bacterial pathogens.
Recent years have witnessed significant advances in unraveling the elegant mechanisms by which intracellular bacterial pathogens induce and/or block apoptosis, which can influence disease progression. This intriguing aspect of the host-pathogen interaction adds another fascinating dimension to our understanding of the exploitation of host cell biology by intracellular bacterial pathogens.
Gao
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LY
Program in Microbial Pathogenesis and Host Defense, University of California at San Fransisco, HSE-201, Box 0654, 513 Parnassus Avenue, San Fransisco, CA 94143-0654, USA.
Kwaik
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YA
D017209:Apoptosis; D001419:Bacteria / Q000235:genetics* / Q000472:pathogenicity*; D001424:Bacterial Infections / Q000382:microbiology / Q000473:pathology*; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D014774:Virulence