Diffuse leptomeningeal oligodendrogliomatosis: radiologic/pathologic correlation.
We present the radiologic and pathologic findings in a boy who presented with diffuse leptomeningeal enhancement and whose clinical status deteriorated over the course of 5 years. During this period, MR images showed progression of the enhancement in the subarachnoid spaces, formation of intraaxial cysts, and hydrocephalus. Autopsy findings revealed diffuse oligodendroglioma throughout the leptomeninges of the brain and spine, with no definite intraaxial focus. The radiologic and pathologic features of diffuse leptomeningeal oligodendrogliomatosis are reviewed.
Armao
D M
DM
Department of Radiology, University of North Carolina School of Medicine, Chapel Hill 27599, USA.
Stone
J
J
Castillo
M
M
Mitchell
K M
KM
Bouldin
T W
TW
Suzuki
K
K
D001921:Brain / Q000378:metabolism / Q000473:pathology; D002648:Child; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology*; D009837:Oligodendroglioma / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology*; D011859:Radiography; D013116:Spinal Cord / Q000378:metabolism / Q000473:pathology