title: Deleterious effects of telescoped bronchial anastomosis in single and bilateral lung transplantation.
abstract: OBJECTIVE
  To compare complication rates of telescoped versus end-to-end bronchial anastomoses in single and bilateral lung transplantation.
  
  
  METHODS
  One hundred and thirty adult lung transplant recipients were evaluated during a seven-year period for the presence of three types of major bronchial anastomotic complications (ischemia, dehiscence, and severe stenosis). Surgical technique, clinical course, and mortality in all patients were reviewed retrospectively.
  
  
  RESULTS
  The three major complications, ischemia, dehiscence, and severe stenosis, were observed in 13 (32%), 10 (24%), and 13 (32%), respectively, of 41 telescoped bronchial anastomoses. In contrast, ischemia, dehiscence, and severe stenosis, occurred in 25 (19%), 14 (10%), and 11 (8%) of 135 end-to end anastomoses. These differences were statistically significant for the occurrence of dehiscence and severe stenosis (p=0.0350 and 0.0004, respectively), and not statistically significant for ischemia (p=0.0846). Five (12%) telescoped anastomoses required stent placement as compared with six (4%) end-to end anastomoses (p=0.1313). Early postoperative pneumonia was more common in the telescoped anastomosis group (57%) as compared to the end-to-end group (35%; p=0.0271). There was a trend to shorter survival in the telescoped anastomosis group (mean survival 1172+/-149 d) as compared to the end-to-end group (mean survival 1542+/-126 d), but these differences did not achieve statistical significance (p=0.2400).
  
  
  CONCLUSIONS
  In single and bilateral lung transplants, telescoped anastomoses are associated with a higher incidence of bronchial anastomotic complications and postoperative pneumonia than end-to-end anastomoses.
authors.affiliation: Department of Surgery, Columbia University, College of Physicians & Surgeons, New York, NY 10032, USA.
authors.forename: E S
authors.initials: ES
authors.lastname: Garfein
authors.forename: C C
authors.initials: CC
authors.lastname: McGregor
authors.forename: M E
authors.initials: ME
authors.lastname: Galantowicz
authors.forename: L L
authors.initials: LL
authors.lastname: Schulman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical / Q000009:adverse effects*; D001980:Bronchi / Q000601:surgery*; D001981:Bronchial Arteries / Q000601:surgery; D005260:Female; D006801:Humans; D007511:Ischemia / Q000453:epidemiology; D016040:Lung Transplantation / Q000379:methods* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D015607:Stents; D015996:Survival Rate