[Radiotherapy for recurrent breast cancer].
The study is concerned with the clinico-radiobiological characteristics of radiotherapy for relapsed breast cancer. Adequate choice of tissue mass to be exposed appeared much more important than any change in focal dose within 50-80 Gy, to achieve higher frequency of locoregional therapeutic effect. No significant noticeable relationship was established between efficacy of recurrence treatment, on the one hand, and such factors as cluster-like lesion, ulceration of tumor and additional excision of a relapsed node, on the other. However, recurrent tumors larger than 3 cm showed lower radiosensitivity involving a sharp rise in the likelihood of dissemination. Radiotherapy for primary tumor did not affect the radiosensitivity of recurrent malignancies but slowed down the rate of ies growth. Also, it might speed up tumor dissemination.
Khmelevskiĭ
E V
EV
Russian Center for Roentgeno-Radiological Research, Ministry of Health of the RF, Moscow.
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology* / Q000532:radiotherapy*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000532:radiotherapy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D016019:Survival Analysis; D016896:Treatment Outcome
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