title: Carcinoma of the uterine cervix: a 3D - CT analysis of dose to the internal, external and common iliac nodes in tandem and ovoid applications.
abstract: OBJECTIVE
  To describe external, internal and common iliac dose rates estimated with 3D-computed tomography (CT) based dose calculations in tandem and ovoid brachytherapy.
  
  
  METHODS
  Thirty patients with carcinoma of the uterine cervix received low dose rate brachytherapy with a CT-compatible Fletcher-Suit-Deldos device. A total of 36 implants were performed with axial CT images used to identify internal iliac, external iliac, and common iliac vessels. Dose rates on the surfaces of these vessels were calculated for the purpose of estimating the dose to their associated lymph nodes.
  
  
  RESULTS
  In 22 out of 72 comparisons, point B overestimated the maximum dose with the external iliac nodes. In 21 out of 72 comparisons, point B overestimated the maximum dose with the internal iliac nodes. In all cases, Point B overestimated the minimum dose to the internal and external iliac nodal chains.
  
  
  CONCLUSIONS
  It was found that Point B dose is similar to the maximum common iliac nodal dose. Patient to patient variability, of Point B dose, warrants further study of dose distributions to the nodal chains. The minimum dose to the external iliac nodal chain at the bifurcation of the nodal chains may provide a useful measure of 'pelvic side wall dose' and deserves further study to see if it can be correlated with pelvic side wall control and complications.
authors.affiliation: Department of Radiation Oncology, REX Hospital, Duke University Medical Center, 4420 Lake Boone Trail, Raleigh, Durham, NC 27607, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Gebara
authors.forename: K J
authors.initials: KJ
authors.lastname: Weeks
authors.forename: E L
authors.initials: EL
authors.lastname: Jones
authors.forename: G S
authors.initials: GS
authors.lastname: Montana
authors.forename: M S
authors.initials: MS
authors.lastname: Anscher
mesh_terms: D001918:Brachytherapy; D005260:Female; D006801:Humans; D007085:Ilium; D008198:Lymph Nodes; D011879:Radiotherapy Dosage; D011881:Radiotherapy, Computer-Assisted; D014057:Tomography, X-Ray Computed; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*