Recurrent infections and chronic colonization by an Escherichia coli clone in the respiratory tract of a patient with severe cystic bronchiectasis.
A 39-year-old woman with cystic bronchiectasis had repeated pulmonary infections from 1996 to 1999, and 6 of a total of 28 isolates of Escherichia coli from sputum specimens were studied. Their identical antibiotype and randomly amplified polymorphic DNA patterns indicated a single clone of E. coli, which persistently colonized the respiratory tract, causing recurrent infections.
Wang
J Y
JY
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Hsueh
P R
PR
Wang
J T
JT
Lee
L N
LN
Yang
P C
PC
Luh
K T
KT
D000328:Adult; D001987:Bronchiectasis / Q000382:microbiology*; D004926:Escherichia coli / Q000145:classification / Q000235:genetics / Q000254:growth & development* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology*; D005260:Female; D006801:Humans; D016133:Polymerase Chain Reaction; D019105:Random Amplified Polymorphic DNA Technique; D012008:Recurrence; D012137:Respiratory System / Q000382:microbiology; D012141:Respiratory Tract Infections / Q000382:microbiology*; D013183:Sputum / Q000382:microbiology