title: Taxonomic study of spirochetes isolated from human periodontal lesions.
abstract: Nineteen strains of spirochetes obtained from subgingival plaque of 19 patients with advanced periodontitis were studied morphologically, biochemically, and genetically and compared with type strains of Treponema denticola and Treponema socranskii. The results showed that 16 strains which biochemically resembled T. denticola could be divided into two groups based on G + C content and DNA homology. Two isolates appeared to belong to the T. socranskii species. One intermediate size isolate did not fit any known Treponema species.
authors.affiliation: Department of Micribiology, Tokyo Dental College, Chiba City, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Fukumoto
authors.forename: K
authors.initials: K
authors.lastname: Okuda
authors.forename: T
authors.initials: T
authors.lastname: Kato
authors.forename: K
authors.initials: K
authors.lastname: Ohta
authors.forename: I
authors.initials: I
authors.lastname: Takazoe
mesh_terms: D000328:Adult; D001426:Bacterial Proteins / Q000235:genetics; D015373:Bacterial Typing Techniques; D001482:Base Composition; D003596:Cytosine / Q000032:analysis; D004269:DNA, Bacterial / Q000032:analysis; D004591:Electrophoresis, Polyacrylamide Gel; D006147:Guanine / Q000032:analysis; D006801:Humans; D010514:Periodontal Pocket / Q000382:microbiology; D010518:Periodontitis / Q000382:microbiology*; D012689:Sequence Homology, Nucleic Acid; D013144:Spirochaetales / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D006147:Guanine; D003596:Cytosine