title: A case of progressive systemic sclerosis complicated by massive pleural effusion with elevated CA125.
abstract: A tumor marker, CA125, is known to increase in the serum or other body fluids in various malignancies such as ovarian cancer. Here we present a case of progressive systemic sclerosis (PSS) with massive pleural effusion, in which CA125 in the serum and pleural fluid were elevated. The serum level of CA125 decreased in accordance with the change of the pleural effusion. CA125 level may be an indicator for the activity of serositis in some cases with collagen vascular diseases.
authors.affiliation: Third Department of Internal Medicine, Kinki University School of Medicine, Osaka Japan.
authors.forename: M
authors.initials: M
authors.lastname: Funauchi
authors.forename: S
authors.initials: S
authors.lastname: Ikoma
authors.forename: H
authors.initials: H
authors.lastname: Yu
authors.forename: M
authors.initials: M
authors.lastname: Sugiyama
authors.forename: M
authors.initials: M
authors.lastname: Ohno
authors.forename: K
authors.initials: K
authors.lastname: Kinoshita
authors.forename: K
authors.initials: K
authors.lastname: Hamada
authors.forename: A
authors.initials: A
authors.lastname: Kanamaru
mesh_terms: D018394:CA-125 Antigen / Q000276:immunology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010996:Pleural Effusion / Q000209:etiology / Q000276:immunology; D012595:Scleroderma, Systemic / Q000150:complications / Q000276:immunology
chemical_list: D018394:CA-125 Antigen