title: Transvaginal ultrasonography combined with pelvic examination in the diagnosis of ovarian endometrioma.
abstract: The aim of this retrospective study was to evaluate the efficacy of TVS and TVS combined with pelvic examination for the diagnosis of ovarian endometrioma. Three hundred and five ovarian masses of 244 patients with either pre-operative or post-operative diagnosis of ovarian tumor and received TVS between January 1, 1996 and December 31, 1998 were included in the study. Of 305 masses, 221 endometriomas of 164 patients were diagnosed histologically. The efficacy of TVS was 84.9 per cent with a sensitivity of 92.3 per cent and specificity of 70.2 per cent. LR+ and LR- were 3.1 and 0.1 respectively. The combination of TVS and pelvic examination with either positive test had a higher sensitivity (98.8%) but lower specificity (26.6%). This combination dramatically improved NPV (97.5%) and LR- (0.05), whereas, the combination with both positive tests had a sensitivity of 78.1 per cent, and specificity of 81.5 per cent. LR+ and LR- were not different from those using TVS alone. In conclusion, the study has shown the role of TVS in the diagnosis of ovarian endometrioma. The combination of TVS and pelvic examination may be useful in ruling out the disease. However, a further prospective study should be performed to confirm the efficacy of the combination.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Weerakiet
authors.forename: A
authors.initials: A
authors.lastname: Wongkularb
authors.forename: M
authors.initials: M
authors.lastname: Rochanawutanon
authors.forename: A
authors.initials: A
authors.lastname: Rojanasakul
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D003131:Combined Modality Therapy; D004715:Endometriosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D019160:Endosonography; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008875:Middle Aged; D010049:Ovarian Diseases / Q000000981:diagnostic imaging* / Q000473:pathology*; D010808:Physical Examination; D012189:Retrospective Studies; D012680:Sensitivity and Specificity