title: Remitting seronegative symmetrical synovitis with pitting oedema associated with chronic lymphocytic leukaemia.
abstract: We describe a case of remitting seronegative symmetrical synovitis with pitting oedema (RS3PE syndrome) in a 67-year-old man. Immunophenotyping studies and histology of biopsy specimens revealed chronic lymphocytic leukaemia (CLL). Polyarthritis and oedema were revealed by small doses of corticosteroids. The association of RS3PE syndrome with rheumatological and malign disorders are discussed.
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, Marmara University, Istanbul, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Ekenel
authors.forename: S
authors.initials: S
authors.lastname: Yavuz
authors.forename: S
authors.initials: S
authors.lastname: Karti
authors.forename: H
authors.initials: H
authors.lastname: Direskeneli
authors.forename: T
authors.initials: T
authors.lastname: Akoğlu
mesh_terms: D004487:Edema / Q000209:etiology*; D005384:Finger Joint; D005534:Foot Diseases / Q000209:etiology*; D006225:Hand; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications*; D008297:Male; D008875:Middle Aged; D013585:Synovitis / Q000209:etiology*