title: Aplasia cutis congenita in an infant of an initial triplet gestation: a case report.
abstract: Aplasia cutis congenita (ACC) is the clinical manifestation of an uncommon group of skin disorders. One postulated etiology is disseminated intravascular coagulation from release of thrombogenic maternal arising from placental injury or fetal demise. This leads to disruption of the ectodermal blood supply responsible for the skin defects. We present a neonate with group V ACC, one of an initial triplet gestation, associated with fetal demise at 14 weeks and formation of a fetus papyraceus. The practice of selective fetal reduction as a result of multiple gestation seen with the use of fertility drugs may in theory increase the incidence of group V ACC.
authors.affiliation: Department of Pediatrics, Overlook Hospital-Atlantic Health Systems, Summit, New Jersey, USA.
authors.forename: S S
authors.initials: SS
authors.lastname: Da-Silva
authors.forename: E O
authors.initials: EO
authors.lastname: Fagbongbe
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001458:Bandages; D004476:Ectodermal Dysplasia / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D005260:Female; D005313:Fetal Death / Q000150:complications*; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D014310:Triplets
chemical_list: D000900:Anti-Bacterial Agents