title: Small cell carcinoma of the esophagus: a case report and review of the literature.
abstract: We present a case of small cell esophageal carcinoma (SCEC) treated with alternated chemotherapy (including cisplatin, etoposide, vincristine, cyclophosphamide and doxorubicin) and irradiation (36 Gy) followed by surgery. Despite a pathological complete response, the patient died of regional disease recurrence 29 months after the diagnosis. We reviewed the available literature on SCEC with regard to the incidence, clinical symptoms, radiological signs, diagnostic workup, therapeutic modalities and prognosis of this malignancy.
authors.affiliation: Department of Radiotherapy, European Institute of Oncology, Milan, Italy. barbara.fossa@ieo.it
authors.forename: B
authors.initials: B
authors.lastname: Jereczek-Fossa
authors.forename: M
authors.initials: M
authors.lastname: Airoldi
authors.forename: E
authors.initials: E
authors.lastname: Vasario
authors.forename: M G
authors.initials: MG
authors.lastname: Redda
authors.forename: G
authors.initials: G
authors.lastname: Valente
authors.forename: R
authors.initials: R
authors.lastname: Orecchia
mesh_terms: D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D004938:Esophageal Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D018714:Radiotherapy, Adjuvant