title: OCT study of fellow eyes of macular holes.
abstract: The aim of this study was to examine the vitreomacular interface in symptom-free fellow eyes of macular holes using optical coherence tomography (OCT) to add information to the pathogenesis of macular holes and to refine prognostic factors for bilateral involvement. Sixty-six patients with a full thickness macular hole in one eye and a symptom-free fellow eye were included in the study between 01/98-05/99. The finding on OCT that a perifoveal vitreous detachment can result in a foveal cyst and subsequently a macular hole confirms the theory of Gass of vitreous traction. Symptom-free fellow eyes with a foveal cyst on OCT represent an elevated risk (55%) for macular hole development. Vitreofoveal separation is probably a good prognostic sign.
authors.affiliation: Dept. of Ophthalmology UZ Leuven, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Spiritus
authors.forename: L
authors.initials: L
authors.lastname: Dralands
authors.forename: P
authors.initials: P
authors.lastname: Stalmans
authors.forename: I
authors.initials: I
authors.lastname: Stalmans
authors.forename: W
authors.initials: W
authors.lastname: Spileers
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012167:Retinal Perforations / Q000175:diagnosis* / Q000209:etiology; D014054:Tomography / Q000379:methods*