A conformational change in the Fc precludes the binding of two Fcgamma receptor molecules to one IgG.
Kato
K
K
Faculty of Pharmaceutical Sciences, Nagoya City University, Mizuho-ku, Nagoya 467-8603, Japan.
Fridman
W H
WH
Arata
Y
Y
Sautès-Fridman
C
C
D000818:Animals; D001665:Binding Sites; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000737:chemistry* / Q000378:metabolism*; D007074:Immunoglobulin G / Q000378:metabolism*; D011487:Protein Conformation; D017452:Receptors, IgG / Q000378:metabolism*; D013329:Structure-Activity Relationship
D007141:Immunoglobulin Fc Fragments; D007074:Immunoglobulin G; D017452:Receptors, IgG