PIH is associated with an increase of trophoblasts circulating in maternal blood.
One of the reason of PIH problems may be due to exposition to placental trophoblast. The objective of the work was to evaluate the number of trophoblast cells deported into maternal peripheral blood of patients with PIH (pregnancy induced hypertension) as compared to normal pregnancy. Trophoblasts have been detected, by cytofluorimetry, in peripheral maternal venous blood of hypertensive woman (15 cases) and normotensive pregnancy (16 cases). Women with PIH had statistically significant (p < 0.005) higher trophoblasts number than that found in normotensive pregnant women without PIH (16 cases). Our results indicate that the increased trophoblasts deportation into peripheral blood could be a marker of the maternal syndrome of PIH.
Heimrath
J
J
Department of Reproduction and Obstetrics, Medical University of Wrocław.
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Duś
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D000328:Adult; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D006973:Hypertension / Q000175:diagnosis*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood*; D014327:Trophoblasts / Q000378:metabolism*