title: [Histology and elementary pathology of the peripheral nerve].
abstract: The lesions which give rise to peripheral neuropathy are induced by a variety of mechanisms. Their etiology can often be established from the results of electrophysiological examination and (or) study of nerve biopsy; knowledge of the etiology will guide the treatment strategy. In this chapter, we discuss typical lesional mechanisms including: axonal involvement (Wallerian degeneration, axonopathies) and demyelinating lesions (whether segmental, indicative of an acquired inflammatory process, or of a more extensive nature, indicative of a genetic origin). The indication for nerve biopsy, which enables identification of the lesions, should be considered on a case by case basis.
authors.affiliation: Service de neurologie CHU Dupuytren, Limoges.
authors.forename: J M
authors.initials: JM
authors.lastname: Vallat
authors.forename: A V
authors.initials: AV
authors.lastname: Vallat-Decouvelaere
mesh_terms: D001369:Axons / Q000473:pathology; D003711:Demyelinating Diseases / Q000503:physiopathology*; D003937:Diagnosis, Differential; D006801:Humans; D010525:Peripheral Nerves / Q000473:pathology; D010523:Peripheral Nervous System Diseases / Q000503:physiopathology*; D014855:Wallerian Degeneration / Q000503:physiopathology
vernacular_title: Histologie et pathologie élémentaire du nerf périphérique.