title: Calculating nucleic acid secondary structure.
abstract: New results for calculating nucleic acid secondary structure by free energy minimization and phylogenetic comparisons have recently been reported. A complete set of DNA energy parameters is now available and the RNA parameters have been improved. Although databases of RNA secondary structures are still derived and expanded using computer-assisted, ad hoc comparative analysis, a number of new computer algorithms combine covariation analysis with energy methods.
authors.affiliation: Department of Biochemistry and Molecular Biophysics, Washington University, St Louis, 63110, USA. zuker@ibc.wustl.edu
authors.forename: M
authors.initials: M
authors.lastname: Zuker
mesh_terms: D000465:Algorithms; D000818:Animals; D004247:DNA / Q000737:chemistry*; D006801:Humans; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry*
chemical_list: D012313:RNA; D004247:DNA