Acute effects of tumor necrosis factor-alpha on testicular germ cell apoptosis and vascular neutrophil adhesion in rats.
Acute effects of tumor necrosis factor-alpha (TNF-alpha) on testicular germ cell apoptosis and vascular neutrophil adhesion were investigated in rats. Acute administration of TNF-alpha did not show a significant increase in percentage of apoptotic tubules and apoptotic germ cells. TNF-alpha administration did not enhance neutrophil adhesion score in the intertubular and subtunical vein. TNF-alpha does not acutely influence testicular germ cell apoptosis and vascular neutrophil adhesion in rats.
Yazawa
H
H
Department of Urology, Yamagata University School of Medicine, Japan.
Sasagawa
I
I
Nakada
T
T
D000728:Androgens / Q000378:metabolism; D000818:Animals; D017209:Apoptosis / Q000187:drug effects*; D002448:Cell Adhesion / Q000187:drug effects*; D005938:Glucocorticoids / Q000378:metabolism; D008297:Male; D051381:Rats; D017382:Reactive Oxygen Species; D013094:Spermatozoa / Q000187:drug effects*; D013737:Testis / Q000166:cytology / Q000187:drug effects*; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology*; D014680:Veins / Q000166:cytology*
D000728:Androgens; D005938:Glucocorticoids; D017382:Reactive Oxygen Species; D014409:Tumor Necrosis Factor-alpha