title: [Multicenter study of the variability and adequacy of antimicrobial therapy for community-acquired pneumonia in adults].
abstract: We performed a study to evaluate the variability and adequacy of prescribing antibiotics in community-acquired pneumonia (CAP) in 10 Spanish hospitals. We studied 452 patients with CAP. Initial empirical administration of antibiotics was prescribed in 90.7&#37; of the cases, 82.5&#37; as monotherapy. Macrolides and third and second generation cephalosporins were the most widely used groups of antibiotics. Penicillin and amoxicillin were only prescribed in 1. 7&#37; of the patients. A significant variability between hospitals was observed. Reference patterns for the use of antibiotics in CAP were devised by a panel of experts. According to the recommendations of this panel, 29&#37; of the total prescriptions were not adequate, with this percentage reaching 65&#37; in outpatients older than 65 years or with comorbidity. This was mainly due to the fact that monotherapy with erythromycin, which was considered inadequate, was the most widely prescribed treatment.
authors.affiliation: Area de Microbiología, Facultad de Medicina, Avda. Ramón y Cajal n(o) 7, 47005 Valladolid.
authors.forename: A
authors.initials: A
authors.lastname: Artero
authors.forename: J M
authors.initials: JM
authors.lastname: Eiros
authors.forename: C
authors.initials: C
authors.lastname: Ochoa
authors.forename: L
authors.initials: L
authors.lastname: Inglada
authors.forename: L
authors.initials: L
authors.lastname: Guerra
authors.forename: L
authors.initials: L
authors.lastname: Armadans
authors.forename: A
authors.initials: A
authors.lastname: Vallano
authors.forename: J B
authors.initials: JB
authors.lastname: Vidal
authors.forename: A
authors.initials: A
authors.lastname: Martínez
authors.forename: A
authors.initials: A
authors.lastname: Lázaro
authors.forename: T
authors.initials: T
authors.lastname: Cerdá
authors.forename: A
authors.initials: A
authors.lastname: Ruiz
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017714:Community-Acquired Infections / Q000188:drug therapy; D003430:Cross-Sectional Studies; D011307:Drug Prescriptions / Q000592:standards; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Estudio multicéntrico de variabilidad e idoneidad de la prescripción antibiótica en la neumonía adquirida en la comunidad del adulto.