title: [Adhesion molecules as the strategic goal of immunotherapy].
abstract: Adhesion molecules are cell surface glycoproteins involved in cell-cell and cell-matrix interactions. They play a central role in leukocyte adhesion to endothelium, transmigration, binding to target cells and cytotoxicity. Many pathological processes underlie abnormal cell-cell interactions in the organism. The adhesion molecules are critical for the communication mechanism between cells in inflammatory and immunologic response. The control of cell-cell adhesive interactions, i.e. modulation of adhesion molecules, is an important strategy for anti-inflammatory therapy. (Ref. 65.)
authors.affiliation: Department of Clinical Immunology, Institute of Preventive and Clinical Medicine, Bratislava. bll@fmed.uniba.sk
authors.forename: M
authors.initials: M
authors.lastname: Horvathova
authors.forename: M
authors.initials: M
authors.lastname: Ferencik
mesh_terms: D000818:Animals; D015815:Cell Adhesion Molecules / Q000276:immunology / Q000502:physiology / Q000627:therapeutic use*; D002450:Cell Communication / Q000502:physiology; D006801:Humans; D007167:Immunotherapy
chemical_list: D015815:Cell Adhesion Molecules
vernacular_title: Adhezívne molekuly ako strategický ciel' imunoterapie.