[Methods of single-nucleotide polymorphism analysis and application to hereditary cancer syndrome].
Single-nucleotide polymorphism analysis is important in all areas of molecular biology. The causative genes of hereditary cancer syndrome have been isolated. Recently, molecular diagnosis of hereditary cancer syndrome has been performed using methods of single-nucleotide polymorphism analysis and the usefulness has been reported. It is considered that progression of molecular biology will be able to contribute to diagnosis (especially pre-symptomatic diagnosis), prevention and treatment of hereditary cancer syndrome in the future.
Mikami
I
I
Department of Molecular Biology, Nippon Medical School.
Nagai
H
H
Harada
H
H
Emi
M
M
D006801:Humans; D009386:Neoplastic Syndromes, Hereditary / Q000175:diagnosis / Q000235:genetics* / Q000517:prevention & control; D020641:Polymorphism, Single Nucleotide; D017422:Sequence Analysis, DNA / Q000379:methods*