title: Gabapentin's effects on hot flashes and hypothermia.
abstract: The author describes six cases in which gabapentin treatment reduced the frequency of hot flashes. In addition, gabapentin treatment enhanced the frequency of hypothermic episodes in a separate patient with known hypothalamic dysfunction. Gabapentin may act directly upon temperature regulatory centers.
authors.affiliation: Department of Neurology, University of Rochester, NY 14642, USA. thomas_guttuso@urmc.rochester.edu
authors.forename: T J
authors.initials: TJ
authors.lastname: Guttuso
mesh_terms: D000085:Acetates / Q000009:adverse effects / Q000627:therapeutic use*; D000328:Adult; D000588:Amines; D003509:Cyclohexanecarboxylic Acids; D018691:Excitatory Amino Acid Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D000077206:Gabapentin; D019584:Hot Flashes / Q000139:chemically induced / Q000188:drug therapy*; D006801:Humans; D007035:Hypothermia / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy; D005680:gamma-Aminobutyric Acid
chemical_list: D000085:Acetates; D000588:Amines; D003509:Cyclohexanecarboxylic Acids; D018691:Excitatory Amino Acid Antagonists; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin