Advances in radiotherapy for carcinoma of the head and neck.
Increasingly, progress in the radiotherapy of carcinomas of the head and neck is being driven by principles of radiobiology. This article discusses some of the major advances in head and neck radiotherapy, including altered fractionation, concomitant chemotherapy, and intensity-modulated radiotherapy, in the context of radiobiologic rationale, potential impact on tumor control, and normal tissue complications.
Morris
M M
MM
Department of Radiation Oncology, Medical College of Virginia Hospitals, Virginia Commonwealth University, Richmond 23298-0058, USA. mmorris@hsc.vcu.edu
Schmidt-Ullrich
R
R
Johnson
C R
CR
D002277:Carcinoma / Q000532:radiotherapy*; D017024:Chemotherapy, Adjuvant; D019583:Dose Fractionation, Radiation; D006257:Head / Q000528:radiation effects; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D009333:Neck / Q000528:radiation effects; D011832:Radiation Injuries / Q000517:prevention & control; D011853:Radiobiology; D020266:Radiotherapy, Conformal