title: Bone marrow transplantation does not correct the hyper IgE syndrome.
abstract: Congenital immunodeficiency in hyper IgE syndrome is characterised by a markedly raised IgE level, recurrent staphylococcal skin infection and pneumatoceles. Standard treatments include anti-staphylococcal antibiotics. We report a severely affected patient in whom successful bone marrow transplantation was followed by reappearance of the immunodeficiency. We conclude that bone marrow transplantation does not cure the immunological features of the hyper IgE syndrome. Bone Marrow Transplantation (2000) 25, 1303-1305.
authors.affiliation: Department of Paediatric Immunology, Newcastle General Hospital, Newcastle upon Tyne, UK.
authors.forename: A R
authors.initials: AR
authors.lastname: Gennery
authors.forename: T J
authors.initials: TJ
authors.lastname: Flood
authors.forename: M
authors.initials: M
authors.lastname: Abinun
authors.forename: A J
authors.initials: AJ
authors.lastname: Cant
mesh_terms: D016026:Bone Marrow Transplantation; D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D007589:Job Syndrome / Q000628:therapy*; D017211:Treatment Failure