title: Clinical evaluation of sodium flouride chewable tablets in dental caries.
abstract: Chewable tablets containing low dosage flouride content were prepared using two varities of celluloses and their in vitro parameters were evaluated. An eighteen month clinical trial revealed that both these formulations were effective in controlling the caries. However, ethyl cellulose is proved to be superior to methylcellulose as a controlled release matrix material in controlling caries. Thus this study recommends ethylcellulose matrix tablets containing low flouride content is an efficacious and cost effective drug device in controlling dental caries.
authors.affiliation: Dept. Pedodontics & Preventive Dentistry, College of Dental Surgery, Manipal Academy of Higher Education, India. SHYAMA99@HOTMAIL.COM
authors.forename: S S
authors.initials: SS
authors.lastname: Maddi
authors.forename: S
authors.initials: S
authors.lastname: Tandon
authors.forename: K S
authors.initials: KS
authors.lastname: Aithal
mesh_terms: D002327:Cariostatic Agents / Q000008:administration & dosage*; D002482:Cellulose / Q000737:chemistry; D002648:Child; D004245:DMF Index; D003731:Dental Caries / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008409:Mastication; D012969:Sodium Fluoride / Q000008:administration & dosage*; D013607:Tablets / Q000737:chemistry
chemical_list: D002327:Cariostatic Agents; D013607:Tablets; D012969:Sodium Fluoride; D002482:Cellulose