A 13-year experience with epilepsy surgery.
Between 1985 and 1997, 563 therapeutic craniotomies were performed: 311 anterior temporal (ATL) and 158 extramesial temporal (XMT) resections, 67 callosotomies, 20 hemispherectomies and 7 multiple subpial transections. Sixty-seven percent of nonlesional ATL cases were seizure free (SF), and 76% of nonlesional ATL cases < or =18 years old were SF. Seventy-eight percent of lesional ATL cases with complete resection were SF. Seventy-three percent of lesional cases < or =18 were SF. Thirty-seven percent of nonlesional XMT cases were SF. Seventy percent of XMT lesional cases with complete resection were SF, and 82% of lesional XMT cases < or =18 were SF. Of the anterior callosotomy cases, there was a > or =90% decrease in generalized tonic-clonic seizures in 50% of patients, and in tonic seizures, drop attacks, absence and myoclonic seizures in approximately 60-70% of patients. Of 20 hemispherectomies, 65% were SF. Of 7 multiple subpial transections, 29% were SF.
Smith
J R
JR
Section of Neurosurgery, Medical College of Georgia, Augusta 30912, USA. deptsurg.jsmith@mail.mcg.edu
Lee
M R
MR
Jenkins
P D
PD
King
D W
DW
Murro
A M
AM
Park
Y D
YD
Lee
G P
GP
Meador
K J
KJ
Loring
D W
DW
D000328:Adult; D002648:Child; D003337:Corpus Callosum / Q000601:surgery; D004827:Epilepsy / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D011183:Postoperative Complications; D012189:Retrospective Studies; D013238:Stereotaxic Techniques; D013702:Temporal Lobe / Q000601:surgery