title: Molecular determinants of presynaptic active zones.
abstract: The presynaptic cytoskeletal matrix (cytomatrix) assembled at active zones has been implicated in defining neurotransmitter release sites. Munc13, Rim, Bassoon and Piccolo/Aczonin are recently identified presynaptic cytomatrix proteins. These multidomain proteins are thought to organize the exocytotic and endocytotic machinery precisely at active zones.
authors.affiliation: Department of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294-0021, USA. garner@nrc.uab.edu
authors.forename: C C
authors.initials: CC
authors.lastname: Garner
authors.forename: S
authors.initials: S
authors.lastname: Kindler
authors.forename: E D
authors.initials: ED
authors.lastname: Gundelfinger
mesh_terms: D000818:Animals; D004705:Endocytosis / Q000502:physiology; D005089:Exocytosis / Q000502:physiology; D009474:Neurons / Q000737:chemistry* / Q000378:metabolism*; D017729:Presynaptic Terminals / Q000737:chemistry* / Q000378:metabolism*