Delta infection in children with chronic viral hepatitis B.
The incidence and clinical features of chronic viral hepatitis B associated with the delta infection were studied in 300 children between one and 14 years in age. Anti-delta was found in 42 (14%) of 300 children with chronic viral hepatitis B, predominantly in patients with chronic active hepatitis who had anti-HBe; exacerbations were found in 11 of 12 children with anti-delta, but in only four of 12 children without these antibodies. These findings confirm the assumption that the process of exacerbation in patients with chronic active hepatitis and anti-HBe may be related to super-infection induced by the delta virus.
Makhmudov
O S
OS
Scientific Research Institute of Pediatrics of the Republic of Uzbekistan, Tashkent.
Inoyatova
F I
FI
Kadirov
B A
BA
Abdumadjidova
S U
SU
D000293:Adolescent; D000375:Aging / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D006508:Hepatitis Antibodies / Q000097:blood*; D006511:Hepatitis B Antigens / Q000097:blood; D019694:Hepatitis B, Chronic / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D019701:Hepatitis D, Chronic / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D006801:Humans; D015994:Incidence; D007223:Infant; D011446:Prospective Studies; D014421:Turkey / Q000453:epidemiology
D006508:Hepatitis Antibodies; D006511:Hepatitis B Antigens