title: Foscarnet-induced electrolyte abnormalities in a bone marrow transplant patient receiving parenteral nutrition.
abstract: Cytomegalovirus (CMV) is a serious complication of immunosuppressed patients receiving bone marrow transplantation. Foscarnet, a pyrophosphate analog, has been used in the treatment of CMV infections. Renal impairment and electrolyte abnormalities are potential adverse reactions associated with the use of foscarnet. We report a case of significant electrolyte changes after initiation of foscarnet in a bone marrow transplant patient receiving parenteral nutrition.
authors.affiliation: Department of General Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA.
authors.forename: L E
authors.initials: LE
authors.lastname: Matarese
authors.forename: R
authors.initials: R
authors.lastname: Speerhas
authors.forename: D L
authors.initials: DL
authors.lastname: Seidner
authors.forename: E
authors.initials: E
authors.lastname: Steiger
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology; D016026:Bone Marrow Transplantation; D003587:Cytomegalovirus / Q000187:drug effects; D003586:Cytomegalovirus Infections / Q000188:drug therapy* / Q000517:prevention & control; D004573:Electrolytes / Q000097:blood*; D017245:Foscarnet / Q000008:administration & dosage / Q000009:adverse effects* / Q000494:pharmacology; D006801:Humans; D008297:Male; D010289:Parenteral Nutrition, Total / Q000009:adverse effects*
chemical_list: D000998:Antiviral Agents; D004573:Electrolytes; D017245:Foscarnet