title: Effects of conjugated linoleic acid. 1. Fatty acid modification of yolks and neonatal fatty acid metabolism.
abstract: The purpose of this study was to evaluate the effects of conjugated linoleic acids (CLA) on neonatal fatty acid metabolism. In this study, layer hens (n = 40) were divided into four equal groups and subjected to the following treatments. Group A served as the control group, Group B received 1 g CLA every other day, Group C received 1 g CLA every 4th d, and Group D was sham-supplemented with 1 g safflower oil every other day. After 4 mo of feeding, Group B hens exhibited an increase in BW and egg size; however, there were no differences noted in feed consumption among the various treatment groups. At the same time, hens were inseminated with a constant dose of pooled rooster semen to evaluate changes in chick liver and yolk fatty acid metabolism during neonatal growth. At hatch and through 6 d of age, there were no significant differences in breakout data (fertility and numbers of early-, mid-, or late-dead chicks) or chick BW, respectively. However, Group B chicks exhibited an increase in liver 18:3n3 and 22:1n9 and a decrease in 20:3n6 and 22:5n3 fatty acids when compared with chicks from Groups A and D. Also noted for Group B chicks, yolk 18:0 fatty acid was higher than that for Group A and D chicks. These results suggest that CLA alters lipid metabolism in growing chicks.
authors.affiliation: Department of Animal Sciences, Purdue University, West Lafayette, Indiana 47907-1151, USA. gator@purdue.edu
authors.forename: M A
authors.initials: MA
authors.lastname: Latour
authors.forename: A A
authors.initials: AA
authors.lastname: Devitt
authors.forename: R A
authors.initials: RA
authors.lastname: Meunier
authors.forename: J J
authors.initials: JJ
authors.lastname: Stewart
authors.forename: B A
authors.initials: BA
authors.lastname: Watkins
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism*; D002645:Chickens / Q000502:physiology*; D004530:Egg Yolk / Q000187:drug effects* / Q000378:metabolism*; D005227:Fatty Acids / Q000378:metabolism*; D005260:Female; D019787:Linoleic Acid / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000378:metabolism
chemical_list: D005227:Fatty Acids; D019787:Linoleic Acid