Factor XIII-mediated inhibition of fibrinolysis and venous leg ulcers.
Densitometric analysis shows an accelerated healing rate and a significantly diminished lesional fibrinolytic activity in patients with venous leg ulcers treated topically with the fibrin-stabilising factor XIII compared with controls.
Herouy
Y
Y
Hellstern
M O
MO
Vanscheidt
W
W
Schöpf
E
E
Norgauer
J
J
D000287:Administration, Topical; D000368:Aged; D003720:Densitometry; D004311:Double-Blind Method; D005169:Factor VIII / Q000494:pharmacology / Q000627:therapeutic use*; D005342:Fibrinolysis / Q000187:drug effects; D006801:Humans; D007871:Leg Ulcer / Q000188:drug therapy*; D014945:Wound Healing / Q000187:drug effects
D005169:Factor VIII