title: Transport between ER and Golgi.
abstract: In the last eighteen months, it has become clear that some classes of proteins are actively recruited into endoplasmic reticulum export carriers, whereas others are exported as bulk-flow cargo. Subsequent transport to the Golgi is mediated by tubulovesicular membranes. The anterograde membrane flow is compensated for by a retrograde pathway, which, in addition to the recycling of membrane and proteins to the endoplasmic reticulum, may play a role in anterograde cargo concentration.
authors.affiliation: Department of Cell Biology, Institute of Biomembranes, Center for Biomedical Genetics, University Medical Center, Utrecht, 3584 CX, The Netherlands. J.Klumperman@lab.azu.nl.
authors.forename: J
authors.initials: J
authors.lastname: Klumperman
mesh_terms: D000818:Animals; D001692:Biological Transport; D002352:Carrier Proteins / Q000378:metabolism; D020755:Coat Protein Complex I / Q000378:metabolism; D018699:Coated Vesicles / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D006056:Golgi Apparatus / Q000378:metabolism*; D010750:Phosphoproteins / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins; D012995:Solubility; D033921:Vesicular Transport Proteins
chemical_list: D002352:Carrier Proteins; D020755:Coat Protein Complex I; D010750:Phosphoproteins; C106113:SEC31 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D033921:Vesicular Transport Proteins