title: [Incidence, severity and mortality of acute respiratory failure in Denmark].
abstract: To determine the incidence, severity and 90-day mortality of acute respiratory failure (ARF), acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) we conducted an eight-week prospective cohort study in 48 Danish ICUs, during which all ICU admissions (n = 6647) > 14 years of age were assessed. ARF was defined as intubation and mechanical ventilation > 24 hrs. ALI and ARDS were defined in accordance with the American-European Consensus Conference criteria. Among the 813 patients included, 552 were diagnosed with ARF, 117 with ALI and 95 with ARDS. The incidences (patients per 100.000/yrs) for ARF were 84.8, for ALI 17.8 and for ARDS 14.6. The 90-day mortality was 46.3% for ARF patients without ALI/ARDS, 47.3% for ALI patients and 46.2% for patients with ARDS. Compared to previously reported figures, the ARDS mortality is in the lower range whereas the incidence is slightly higher. This probably reflects a broader selection of patients when using the consensus criteria to define the ARDS population as opposed to definitions previously used.
authors.affiliation: Anaestesiologisk afdeling, Amtssygehuset i Herlev. ARF-studiegruppe.
authors.forename: K
authors.initials: K
authors.lastname: Antonsen
authors.forename: J
authors.initials: J
authors.lastname: Wetterslev
authors.forename: J
authors.initials: J
authors.lastname: Bonde
mesh_terms: D000328:Adult; D000368:Aged; D003718:Denmark / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012128:Respiratory Distress Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality; D012131:Respiratory Insufficiency / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality; D012720:Severity of Illness Index; D015996:Survival Rate
vernacular_title: Incidens, svaerhedsgrad og mortalitet af akut lungesvigt i Danmark.