title: Nucleotide sequence analyses of partial envgp46 gene of human T-lymphotropic virus type I from inhabitants of Fujian Province in Southeast China.
abstract: Partial sequences from the env(gp46) gene of two human T-lymphotropic virus type I (HTLV-I) isolates (LIN and WEN) obtained from inhabitants of Fujian Province in southeast China were analyzed. A phylogenetic tree was constructed from these sequence data and those of other known HTLV-I isolates from all over the world. Comparisons of the LIN and WEN nucleotide sequences with other HTLV-I isolates showed diversity ranging from 0.73 to 7.00% for LIN and from 0.87 to 7.00% for WEN. Sequences of isolates LIN, WEN, MT-2, TSP1, and CH were most closely related, and the phylogenetic tree showed that all belong to the widespread subtype A of the cosmopolitan group. These preliminary data indicate that HTLV-I isolates from Fujian Province, China are closely related to HTLV-I strains from Japan and the Caribbean.
authors.affiliation: Institute of Blood Transfusion, Chinese Academy of Medical Sciences and Peking Union College, Beijing. caofengcf@hotmail.com
authors.forename: F
authors.initials: F
authors.lastname: Cao
authors.forename: Y
authors.initials: Y
authors.lastname: Ji
authors.forename: R
authors.initials: R
authors.lastname: Huang
authors.forename: T
authors.initials: T
authors.lastname: Zhao
authors.forename: T J
authors.initials: TJ
authors.lastname: Kindt
mesh_terms: D001483:Base Sequence; D002681:China; D017931:DNA Primers / Q000235:genetics; D015686:Gene Products, env / Q000235:genetics* / Q000276:immunology*; D015752:Genes, env; D014644:Genetic Variation; D015486:HTLV-I Antigens / Q000235:genetics*; D015490:HTLV-I Infections / Q000821:virology; D015368:Human T-lymphotropic virus 1 / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D015682:Retroviridae Proteins, Oncogenic / Q000235:genetics* / Q000276:immunology*
chemical_list: D017931:DNA Primers; D015686:Gene Products, env; D015486:HTLV-I Antigens; D015682:Retroviridae Proteins, Oncogenic; C055266:gp46 protein, Human T-cell leukemia virus type I