title: Surveillance of antimicrobial resistance in Escherichia coli strains isolated from pigs at Spanish slaughterhouses.
abstract: Antimicrobial resistance can make the efficient treatment of bacterial infections in humans and animals more difficult. Antimicrobial use in food animals may be one of the factors contributing to resistance. The Spanish surveillance network VAV has established a baseline of antimicrobial resistance in Escherichia coli strains from healthy pigs. Minimum inhibitory concentration and patterns of resistance to antimicrobials used in animals and humans were determined for 205 faecal strains isolated in a sampling frame of four slaughterhouses in Spain from 220 pigs in 1998. Higher levels of resistance were seen against antimicrobial agents authorised for use in food animals especially tetracycline, sulphonamides, trimethoprim and amoxycillin. All isolates were susceptible to antimicrobials employed mainly in humans such as ceftazidime, cefotaxime, imipenem, aztreonam and amikacin.
authors.affiliation: Red de Vigilancia de Resistencias Antibióticas en Bacterias de Origen Veterinario (VAV), Departamento de Patología Animal I (Sanidad Animal), Facultad de Veterinaria, Universidad Complutense de Madrid, 28040, Madrid, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Teshager
authors.forename: I A
authors.initials: IA
authors.lastname: Herrero
authors.forename: M C
authors.initials: MC
authors.lastname: Porrero
authors.forename: J
authors.initials: J
authors.lastname: Garde
authors.forename: M A
authors.initials: MA
authors.lastname: Moreno
authors.forename: L
authors.initials: L
authors.lastname: Domínguez
mesh_terms: D000003:Abattoirs; D000583:Amikacin / Q000494:pharmacology; D000658:Amoxicillin / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001398:Aztreonam / Q000494:pharmacology; D002439:Cefotaxime / Q000494:pharmacology; D002442:Ceftazidime / Q000494:pharmacology; D003625:Data Collection; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics; D005243:Feces / Q000382:microbiology; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013030:Spain; D013449:Sulfonamides / Q000494:pharmacology; D013552:Swine / Q000382:microbiology*; D013752:Tetracycline / Q000494:pharmacology; D014295:Trimethoprim / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D013449:Sulfonamides; D015378:Imipenem; D000658:Amoxicillin; D000583:Amikacin; D002442:Ceftazidime; D014295:Trimethoprim; D013752:Tetracycline; D001398:Aztreonam; D002439:Cefotaxime