title: [Vocal cord dysfunction simulating severe corticoid-dependent asthma].
abstract: We report a case of severe asthma initially considered as cortico-resistant. Clinical analysis of dyspneic attacks demonstrated they were atypical, sometimes associated with dysphonia and syncopes. Severity of clinical presentation was discordant with lung function tests. The diagnosis of vocal cord dysfunction was confirmed by ENT specialized examination. It showed paradoxal inspiratory adduction of the vocal cords triggered by exercise. Treatment remained however difficult, based on speech therapy, relaxation and psychotherapy. This observation underlines the influence of searching a vocal cord dysfunction in cortico-dependent asthma, especially if clinical presentation is atypical. Treatment of this condition may allow to decrease steroid treatment in such patients.
authors.affiliation: Service de Pneumologie et Allergologie, Hôpital de Rangueil, Toulouse.
authors.forename: P
authors.initials: P
authors.lastname: Debove
authors.forename: P
authors.initials: P
authors.lastname: Birot
authors.forename: S
authors.initials: S
authors.lastname: Doussau-Thuron
authors.forename: R
authors.initials: R
authors.lastname: Pelet
authors.forename: M
authors.initials: M
authors.lastname: Calas
authors.forename: A
authors.initials: A
authors.lastname: Didier
authors.forename: P
authors.initials: P
authors.lastname: Léophonte
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001249:Asthma / Q000175:diagnosis* / Q000188:drug therapy; D001993:Bronchodilator Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004351:Drug Resistance; D004417:Dyspnea / Q000175:diagnosis; D005260:Female; D006801:Humans; D001239:Inhalation / Q000502:physiology; D007818:Laryngeal Diseases / Q000175:diagnosis* / Q000628:therapy; D011613:Psychotherapy; D012064:Relaxation Therapy; D013070:Speech Therapy; D013224:Status Asthmaticus / Q000175:diagnosis / Q000188:drug therapy; D013575:Syncope / Q000175:diagnosis; D014827:Vocal Cords / Q000503:physiopathology*; D014832:Voice Disorders / Q000175:diagnosis
chemical_list: D000305:Adrenal Cortex Hormones; D001993:Bronchodilator Agents
vernacular_title: Dysfonction des cordes vocales simulant un asthme sévère cortico-dépendant.