[Risk factors of the lower extremity amputation and mortality of necrotic inflammation of the foot in patients with diabetes mellitus].
The comparative analysis of the clinical examination, biochemical and morphological investigations data in 75 patients with diabetes mellitus (DM) of the 1st type and in 341 patients with DM of the 2nd type, complicated by necrotically-inflammatory damage of foot (NIDF), was done. Amputation of lower extremity (LE) on the hip level was performed in 21.1%, on the knee one--in 3.6% of patients. Twenty eight, or 6.7%, patients died. There were following risk factors for the high level of the LE amputation and mortality: the senior age of patients, long duration of the DM course, the presence of the metabolism and rheologic properties of blood disorders, progressing atherosclerosis of the main arteries of hip and crus, the anamnesis data concerning other DM complications (nephropathy, anemia), and an ischemic heart disease, myocardium infarction, disorders of cerebral blood supply as well.
Fedorenko
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D000328:Adult; D000671:Amputation, Surgical / Q000379:methods; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D017719:Diabetic Foot / Q000150:complications / Q000401:mortality / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012307:Risk Factors; D015996:Survival Rate
Faktory ryzyku vykonannia vysokoï amputatsiï nyzhn'oï kintsivky i letalnosti pry nekrotychno-zapal'nomu urazhenni stopy u khvorykh na tsukrovnyĭ diabet.