title: Preliminary experience with anterior cervical microdiscectomy and interbody titanium cage fusion (Novus CT-Ti) in patients with cervical disc disease.
abstract: BACKGROUND
  Although the use of intervertebral fusion after anterior microdiscectomy in cervical disc disease remains controversial, a new surgical device is proposed for use in intervertebral fusion instead of bone graft.
  
  
  METHODS
  This retrospective study at the Department of Neurosurgery, Cardarelli Hospital, Naples, from January 1993 to December 1998, compares the results of surgery on 58 patients with anterior microdiscectomy and intervertebral bone graft fusion (Group A) (ADIBG) with a group of 52 patients who underwent anterior microdiscectomy and intervertebral titanium cage fusion (Group B) (ADITC) in cervical radiculopathy and spondylotic myelopathy. In both groups a "radical discectomy" was performed under the operating microscope. In group A, interbody fusion was performed with autologous tricortical bone graft. In group B, a new type of titanium device (Novus CT-Ti) was used (Sofamor Danek Group).
  
  
  RESULTS
  There was no collapse or extrusion of the device and no complications at the donor site (the bone fragments used to fill the cage were taken from osteophytes or vertebral body fragments). The use of this device provides immediate stabilization, reduces or eliminates pain, promotes bone fusion between the vertebrae adjacent to the cage by allowing bone growth through the cage, reestablishes and maintains the intervertebral space, reduces the average hospitalization time, and allows a quicker return to work.
  
  
  CONCLUSIONS
  Patients who underwent ADITC did well and benefited from the surgery. Those who underwent ADITC did better than those who underwent ADIBG in regard to function, relief from pain, and complications. Early and good stability of the cervical spine seems to be the main advantage of using titanium cages.
authors.affiliation: Department of Neurosurgery, Cardarelli Hospital, Naples, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Profeta
authors.forename: R
authors.initials: R
authors.lastname: de Falco
authors.forename: G
authors.initials: G
authors.lastname: Ianniciello
authors.forename: L
authors.initials: L
authors.lastname: Profeta
authors.forename: A
authors.initials: A
authors.lastname: Cigliano
authors.forename: A I
authors.initials: AI
authors.lastname: Raja
mesh_terms: D002574:Cervical Vertebrae / Q000601:surgery*; D017586:Diskectomy / Q000379:methods*; D005260:Female; D006801:Humans; D007403:Intervertebral Disc / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011843:Radiculopathy / Q000209:etiology / Q000601:surgery*; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000150:complications / Q000601:surgery*; D013123:Spinal Fusion / Q000379:methods*; D014025:Titanium
chemical_list: D014025:Titanium