Successful treatment of invasive nasal cryptococcosis in a ferret.
Invasive cryptococcal rhinitis due to Cryptococcus neoformans var gattii was diagnosed in a castrated, 5-year-old, albino ferret with subcutaneous swelling of the nasal bridge. The diagnosis was based on histology, needle aspirate cytology and positive culture on Sabouraud's dextrose agar and birdseed agar. The ferret was successfully treated using a long course of itraconazole (25 to 33 mg orally once daily with food) subsequent to surgical debulking of the lesion, using sequential cryptococcal antigen titre determinations to guide therapy.
Malik
R
R
Department of Veterinary Clinical Sciences, University of Sydney, New South Wales.
Martin
P
P
McGill
J
J
Martin
A
A
Love
D N
DN
D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use*; D000946:Antigens, Fungal / Q000302:isolation & purification; D003453:Cryptococcosis / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D003455:Cryptococcus neoformans / Q000276:immunology / Q000302:isolation & purification; D005289:Ferrets; D017964:Itraconazole / Q000627:therapeutic use*; D008297:Male; D012220:Rhinitis / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*
D000935:Antifungal Agents; D000946:Antigens, Fungal; D017964:Itraconazole