title: Perineural spread of squamous cell carcinoma of the lip: the importance of follow-up and collaboration.
abstract: Perineural spread (PNS) of mucosal squamous cell carcinoma of the head and neck region occurs with a reported frequency of 2% to more than 27%. Patients previously diagnosed with and treated for head and neck cancer should be closely followed by both their physician and their dentist in order to facilitate the coordination of care. This case history demonstrates the results that can occur when a team approach to head and neck cancer is not followed, especially in a patient who is an infrequent and somewhat reluctant health care utilizer. Despite mandibular pain, the patient, who had a history of a carcinoma of the lower lip and had developed PNS, was not referred to a dentist. In patients with a previous history of squamous cell carcinoma, sensory and/or motor changes must be closely monitored when there is a suspicion of PNS. The outcome of this case supports improved collaborations between physicians and dentists in following head and neck cancer patients.
authors.affiliation: Department of Oral Diagnosis and Radiology, Case Western Reserve University (CWRU), School of Dentistry, Cleveland, OH 44106-4905, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Pyle
authors.forename: J
authors.initials: J
authors.lastname: Zak
authors.forename: M
authors.initials: M
authors.lastname: Bath
authors.forename: D R
authors.initials: DR
authors.lastname: Sawyer
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D003390:Cranial Nerve Neoplasms / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008048:Lip Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009361:Neoplasm Invasiveness; D014057:Tomography, X-Ray Computed; D020433:Trigeminal Nerve Diseases / Q000473:pathology*