Emergence of fluconazole-resistant sterol 14-demethylase P450 (CYP51) in Candida albicans is a model demonstrating the diversification mechanism of P450.
Aoyama
Y
Y
Kudo
M
M
Asai
K
K
Okonogi
K
K
Horiuchi
T
T
Gotoh
O
O
Yoshida
Y
Y
D000935:Antifungal Agents / Q000494:pharmacology; D002176:Candida albicans / Q000201:enzymology* / Q000235:genetics; D002462:Cell Membrane / Q000201:enzymology; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics* / Q000378:metabolism; D004351:Drug Resistance / Q000235:genetics*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004926:Escherichia coli; D015725:Fluconazole / Q000494:pharmacology*; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism; D005800:Genes, Fungal / Q000235:genetics; D010088:Oxidoreductases / Q000235:genetics* / Q000378:metabolism; D011110:Polymorphism, Genetic; D058886:Sterol 14-Demethylase; D014170:Transformation, Genetic
D000935:Antifungal Agents; D004791:Enzyme Inhibitors; D005656:Fungal Proteins; D015725:Fluconazole; D003577:Cytochrome P-450 Enzyme System; D010088:Oxidoreductases; D058886:Sterol 14-Demethylase