title: Matrix metalloproteinases (MMP-8, -13, and -14) interact with the clotting system and degrade fibrinogen and factor XII (Hagemann factor).
authors.affiliation: University Bielefeld, Faculty of Chemistry, Department of Biochemistry, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Tschesche
authors.forename: A
authors.initials: A
authors.lastname: Lichte
authors.forename: O
authors.initials: O
authors.lastname: Hiller
authors.forename: A
authors.initials: A
authors.lastname: Oberpichler
authors.forename: F H
authors.initials: FH
authors.lastname: Büttner
authors.forename: E
authors.initials: E
authors.lastname: Bartnik
mesh_terms: D020134:Catalytic Domain; D017364:Collagenases / Q000502:physiology*; D004789:Enzyme Activation; D005174:Factor XII / Q000378:metabolism*; D005342:Fibrinolysis / Q000502:physiology*; D006801:Humans; D006868:Hydrolysis; D007610:Kallikreins; D053509:Matrix Metalloproteinase 13; D020784:Matrix Metalloproteinase 8 / Q000502:physiology*; D053504:Matrix Metalloproteinases, Membrane-Associated; D008666:Metalloendopeptidases / Q000737:chemistry / Q000502:physiology*; D008958:Models, Molecular; D010446:Peptide Fragments / Q000378:metabolism; D011487:Protein Conformation; D013379:Substrate Specificity; D013917:Thrombin / Q000494:pharmacology
chemical_list: D010446:Peptide Fragments; D005174:Factor XII; D007610:Kallikreins; D013917:Thrombin; D017364:Collagenases; C507079:MMP13 protein, human; D053509:Matrix Metalloproteinase 13; D053504:Matrix Metalloproteinases, Membrane-Associated; D008666:Metalloendopeptidases; D020784:Matrix Metalloproteinase 8