Pancreatic aspects of cystic fibrosis and other inherited causes of pancreatic dysfunction.
Causes of pancreatic dysfunction in childhood can be divided into two general categories: (1) hereditary conditions that directly affect the pancreas and (2) acquired disorders in which loss of pancreatic function is a secondary phenomenon. This article discusses genotypes and phenotypes, clinical features, Shwachman-Diamond syndrome, isolated enzyme deficiencies, and other topics.
Durie
P R
PR
Department of Pediatrics, University of Toronto, Canada. peter.durie@sickkids.on.ca
D002648:Child; D003550:Cystic Fibrosis / Q000175:diagnosis / Q000235:genetics*; D010188:Exocrine Pancreatic Insufficiency / Q000175:diagnosis / Q000235:genetics*; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005838:Genotype; D006801:Humans; D010641:Phenotype; D013577:Syndrome