title: [A case of occupational contact dermatitis due to hydroxylamine].
abstract: A 36-year-old man, working in a chemical industry, had a generalized pruritic eruption. A forty-eight hour patch test revealed positivity for 1% hydroxylamine. Prevention of exposure to this chemical resulted in a dramatic improvement of the symptoms. Based on these findings, we diagnosed this case as occupational contact dermatitis due to hydroxylamine. There has been few case reports of contact dermatitis due to hydroxylamine. Histopathological examination revealed a marked spongiosis and a spongiotic bulla formation in the epidermis and follicular infundibulum, suggesting an allergic reaction.
authors.affiliation: Department of Dermatology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Izu
authors.forename: O
authors.initials: O
authors.lastname: Yamamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Suenaga
authors.forename: M
authors.initials: M
authors.lastname: Asahi
mesh_terms: D000328:Adult; D002617:Chemical Industry; D003877:Dermatitis, Contact / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D009783:Dermatitis, Occupational / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D019811:Hydroxylamine / Q000009:adverse effects* / Q000276:immunology; D008297:Male; D010328:Patch Tests; D012867:Skin / Q000276:immunology / Q000473:pathology
chemical_list: D019811:Hydroxylamine