title: [Sensitivity to vancomycin and teicoplanin of coagulase-negative staphylococci isolated from clinical specimens].
abstract: The frequency of resistance and elevated resistance to teicoplanin and vancomycin among 689 strains of coagulase-negative staphylococci isolated in one year from clinical specimens was determined. Using ATB.STAPH test, a resistance was shown mainly among strains of S. epidermidis and S. haemolyticus. The elevated resistance to teicoplanin was much more frequently observed than to vancomycin. About 27% of isolated strains of S. haemolyticus and 6.8% of S. epidermidis were classified as resistant. Among other species only single strains were recognised as resistant: one strain of S. xylosus, one of S. cohni and one of S. intermedius. 94.7% of S. epidermidis and 100% of S. haemolyticus strains classified as resistant to teicoplanin in ATB showed MIC values 14 mg/l. Moreover it was shown that 26.3% of these strains of S. epidermidis and 33.3% of S. haemolyticus had MBC of teicoplanin values equal to or higher than 32 mg/l.
authors.affiliation: Zakład Mikrobiologii Lekarskiej A.M. w Warszawie.
authors.forename: G
authors.initials: G
authors.lastname: Młynarczyk
authors.forename: A
authors.initials: A
authors.lastname: Młynarczyk
authors.forename: M
authors.initials: M
authors.lastname: Luczak
authors.forename: J
authors.initials: J
authors.lastname: Jeljaszewicz
mesh_terms: D003030:Coagulase / Q000032:analysis; D004352:Drug Resistance, Microbial; D008826:Microbial Sensitivity Tests; D013210:Staphylococcus / Q000145:classification / Q000187:drug effects* / Q000201:enzymology; D017334:Teicoplanin / Q000494:pharmacology*; D014640:Vancomycin / Q000494:pharmacology*
chemical_list: D003030:Coagulase; D017334:Teicoplanin; D014640:Vancomycin
vernacular_title: Wrazliwość na wankomycyne i teikoplanine koagulazo-ujemnych szczepów z rodzaju Staphylococcus izolowanych z materiału klinicznego.