title: Structural hair shaft abnormalities in hypomelanosis of ito and other ectodermal dysplasias.
abstract: Hair samples from patients with different ectodermal dysplasias; hypohidrotic ectodermal dysplasia, pachyonychia congenita, tricho-dento-osseous syndrome, tricho-rhino-phalangeal syndrome, and hypomelanosis of Ito were investigated using a scanning electron microscope. The hairs of the patients showed different structural abnormalities; twisted hairs, longitudinal grooves, trichorrhexis nodosa as well as variations in the hair caliber. Hair shaft abnormalities, as in our patients with tricho-dento-osseous syndrome, and hypomelanosis of Ito have so far not been described.
authors.affiliation: Department of Dermatologyl, Ulleval Hospital, University of Oslo, Norway.
authors.forename: E
authors.initials: E
authors.lastname: Selvaag
authors.forename: A M
authors.initials: AM
authors.lastname: Aas
authors.forename: S
authors.initials: S
authors.lastname: Heide
mesh_terms: D002675:Child, Preschool; D004476:Ectodermal Dysplasia / Q000150:complications* / Q000235:genetics; D005260:Female; D006197:Hair / Q000648:ultrastructure*; D006201:Hair Diseases / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning / Q000379:methods; D010859:Pigmentation Disorders / Q000150:complications* / Q000235:genetics; D014960:X Chromosome / Q000235:genetics