[The comparative characteristics of the pathogenic action of Vibrio cholerae of the non-O1 group O139 serovar and of the O1 group on the intestinal APUD system of suckling rabbits].
The comparative study of the enteropathogenic action of V. cholerae strains of group non-O1, serovar O139, and group O1 with different virulence on the APUD system of the intestine of suckling rabbits after intraenteral infection revealed that V. cholerae of group non-O1 induced inflammatory changes in the intestine and the pronounced toxic lesion of parenchymal organs. This was accompanied by a decrease in the number of apudocytes and an increase in the functional tension of the APUD system. After the infection of the animals with V. cholerae of group O1 changes in the APUD system and internal organs directly depended on the virulence of the microbes and the infective dose.
Bugorkova
S A
SA
Research Institute for Plague Control Microbe, Saratov, Russia.
Gracheva
I V
IV
Isupov
I V
IV
Valova
T V
TV
Plotnikov
O P
OP
D001078:APUD Cells / Q000382:microbiology* / Q000473:pathology; D000818:Animals; D000833:Animals, Suckling; D002771:Cholera / Q000382:microbiology / Q000473:pathology; D007422:Intestines / Q000382:microbiology* / Q000473:pathology; D011817:Rabbits; D012703:Serotyping; D013997:Time Factors; D014734:Vibrio cholerae / Q000145:classification / Q000472:pathogenicity*; D014774:Virulence
Sravnitel'naia kharakteristika patogennogo deĭstviia kholernykh vibrionov ne O1 gruppy O139 serovara i O1 gruppy na APUD-sistemu kishechnika krol'chat-sosunkov.