Inherited protein-C deficiency, factor V G 1691 A and FV A 4070 G mutations in a child with internal cerebral venous thrombosis.
Common systemic disorders that cause cerebral venous thrombosis (CVT) in children include dehydration, trauma, infection and haematological diseases. No cause for CVT is identified in one quarter of all cases. We report a child with thalamic infarcts due to internal CVT who had congenital heterozygous protein-C deficiency, factor V G 1691 A and A 4070 G mutations.
Sipahi
T
T
Department of Paediatric Haematology, Dr Sami Ulus Children's Medical Centre, Altindağ, Ankara, Turkey.
Uner
C
C
Yildiz
Y T
YT
Akar
N
N
D002550:Cerebral Veins; D005165:Factor V / Q000235:genetics*; D005260:Female; D006801:Humans; D007223:Infant; D017354:Point Mutation; D020151:Protein C Deficiency / Q000150:complications / Q000151:congenital* / Q000235:genetics*; D020246:Venous Thrombosis / Q000150:complications*
C095381:factor V Leiden; D005165:Factor V