title: Laryngotracheobronchial involvement in a patient with nonendemic rhinoscleroma.
abstract: We report the first case of rhinoscleroma in an Israeli citizen, a former sailor with a transatlantic shipping company. Characteristic histologic changes from a tracheal biopsy and isolation of Klebsiella rhinoscleromatis from a blood culture after diagnostic bronchoscopy confirmed the diagnosis. Extreme delay in the diagnosis, a not uncommon feature in nonendemic areas, was associated with severe advanced laryngotracheobronchial disease. Treatment with quinolones was followed by significant improvement, but the patient died 1 month after presentation, apparently from upper airway obstruction.
authors.affiliation: Division of Pulmonary Medicine, Rambam Medical Cente, Haifa, Israel. m_yigla@rambam.health.gov.il
authors.forename: M
authors.initials: M
authors.lastname: Yigla
authors.forename: O
authors.initials: O
authors.lastname: Ben-Izhak
authors.forename: I
authors.initials: I
authors.lastname: Oren
authors.forename: N
authors.initials: N
authors.lastname: Hashman
authors.forename: F
authors.initials: F
authors.lastname: Lejbkowicz
mesh_terms: D000328:Adult; D001706:Biopsy; D001982:Bronchial Diseases / Q000175:diagnosis* / Q000473:pathology; D001999:Bronchoscopy; D003937:Diagnosis, Differential; D006801:Humans; D007711:Klebsiella pneumoniae / Q000302:isolation & purification; D007818:Laryngeal Diseases / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D012226:Rhinoscleroma / Q000175:diagnosis* / Q000473:pathology; D014132:Trachea / Q000473:pathology; D014133:Tracheal Diseases / Q000175:diagnosis* / Q000473:pathology