title: [Retinal vasculopathy associated with Berger's IgA nephropathy].
abstract: OBJECTIVE
  Ophthalmological complications associated with Berger's IgA nephropathy comprise scleritis, episcleritis, keratoconjunctivitis as well as anterior uveitis. We present a new association of IgA nephropathy with a retinal vasculopathy.
  
  
  METHODS
  Presentation of two clinical cases.
  
  
  RESULTS
  Two patients presented with hematuria and epistaxis associated with a retinal vasculopathy characterised by teleangiectasies, capillary occlusion with retinal hemorrhages, neovascularisations and macular edema with decreased visual acuity. Fluorescein angiography showed zones of non-perfusion as well as vasculitic changes. A general medical exam revealed a normal arterial pressure but a slightly elevated creatinine. Immunological investigations for the presence of antibodies showed no positive results. Renal biopsy demonstrated mesangial proliferations with diffuse deposits of IgA. Over the course of a 2 year follow-up some of the retinal changes regressed under treatment with cortisone and visual acuity returned to normal. The teleangiectasies showed no progression.
  
  
  CONCLUSIONS
  Berger's IgA nephropathy can be associated with a retinal vasculopathy which may be due to local deposition of IgA immune complexes in the retinal vessels.
authors.affiliation: Hôpital Ophtalmique Jules Gonin, Université de Lausanne, Schweiz. tjw@pingnet.ch
authors.forename: T J
authors.initials: TJ
authors.lastname: Wolfensberger
authors.forename: B
authors.initials: B
authors.lastname: Piguet
authors.forename: Z J
authors.initials: ZJ
authors.lastname: Gregor
authors.forename: A C
authors.initials: AC
authors.lastname: Bird
mesh_terms: D000328:Adult; D000936:Antigen-Antibody Complex / Q000276:immunology; D004487:Edema / Q000276:immunology; D005451:Fluorescein Angiography; D005922:Glomerulonephritis, IGA / Q000150:complications* / Q000276:immunology; D006801:Humans; D007105:Immune Complex Diseases / Q000150:complications; D007070:Immunoglobulin A / Q000276:immunology; D008297:Male; D012164:Retinal Diseases / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology*; D012166:Retinal Hemorrhage / Q000276:immunology; D015861:Retinal Neovascularization / Q000276:immunology; D012171:Retinal Vessels / Q000473:pathology*; D013684:Telangiectasis / Q000276:immunology; D014792:Visual Acuity / Q000276:immunology
chemical_list: D000936:Antigen-Antibody Complex; D007070:Immunoglobulin A
vernacular_title: Retinale Vaskulopathie assoziiert mit Bergers IgA-Nephropathie.