title: Seventeen more novel HLA-A locus alleles.
abstract: This paper describes seventeen novel HLA-A locus alleles: A*0106, *0235, *0236, *0237, *1105, *2302, *2303, *24032, *2422, *2424, *2503, *2613, *3007, *3203, *3204, *6809 and *6810. All alleles were identified due to unexpected probe reaction patterns during routine SSOP typing. Exons 2 and 3 of these alleles were subsequently characterized by DNA sequencing. The alleles represent a shuffling of sequence motifs, likely by interallelic conversion, expanding the diversity of the HLA system.
authors.affiliation: Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC, USA.
authors.forename: J
authors.initials: J
authors.lastname: Ellis
authors.forename: N
authors.initials: N
authors.lastname: Steiner
authors.forename: C
authors.initials: C
authors.lastname: Kosman
authors.forename: V
authors.initials: V
authors.lastname: Henson
authors.forename: W
authors.initials: W
authors.lastname: Mitton
authors.forename: R
authors.initials: R
authors.lastname: Koester
authors.forename: J
authors.initials: J
authors.lastname: Ng
authors.forename: R J
authors.initials: RJ
authors.lastname: Hartzman
authors.forename: C K
authors.initials: CK
authors.lastname: Hurley
mesh_terms: D000483:Alleles; D001483:Base Sequence; D005091:Exons / Q000235:genetics; D014644:Genetic Variation; D015234:HLA-A Antigens / Q000235:genetics* / Q000276:immunology; D006801:Humans; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA
chemical_list: D015234:HLA-A Antigens