title: Imaging pulmonary blood flow and perfusion using phase-sensitive selective inversion recovery.
abstract: A technique is described for imaging pulmonary blood flow using a phase-sensitive selective inversion recovery (PS-SIR) sequence. PS-SIR image reconstruction provides excellent contrast, differentiating fully relaxed inflowing blood from inverted blood and lung tissue. The magnetization of the inverted tissues remains negative at any inversion delay less than that at which the magnetization of the lung tissue is nulled, whereas that of the fully relaxed inflowing blood is always positive. Pulmonary blood flow can be observed by tracking the propagation of the pixels with positive values. Five healthy volunteers were imaged. The normal pattern of blood flow advancing from the central arteries toward the peripheries and into the lung parenchyma with return toward the center via draining veins was depicted. The method offers promise for evaluating pulmonary blood flow without the need for image subtraction or contrast administration. Magn Reson Med 43:793-795, 2000.
authors.affiliation: Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA. vmmai@caregroup.harvard.edu
authors.forename: V M
authors.initials: VM
authors.lastname: Mai
authors.forename: Q
authors.initials: Q
authors.lastname: Chen
authors.forename: A A
authors.initials: AA
authors.lastname: Bankier
authors.forename: M
authors.initials: M
authors.lastname: Zhang
authors.forename: K D
authors.initials: KD
authors.lastname: Hagspiel
authors.forename: S S
authors.initials: SS
authors.lastname: Berr
authors.forename: R R
authors.initials: RR
authors.lastname: Edelman
mesh_terms: D000328:Adult; D000792:Angiography; D001783:Blood Flow Velocity; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008875:Middle Aged; D011651:Pulmonary Artery / Q000033:anatomy & histology* / Q000502:physiology*; D011652:Pulmonary Circulation; D012016:Reference Values; D012680:Sensitivity and Specificity