IVIAT: a novel method to identify microbial genes expressed specifically during human infections.
In vivo induced antigen technology (IVIAT) is a novel technology that can quickly and easily identify in vivo induced genes in human infections, without the use of animal models. This technology is expected to facilitate the discovery of new targets for vaccines, antimicrobials and diagnostic strategies in a wide range of microbial pathogens.
Handfield
M
M
Center for Molecular Microbiology and Dept of Oral Biology, College of Dentistry, University of Florida, Box 100424 JHMHSC, 1600 SW Archer Rd, Gainesville, FL 32610-0424, USA. mhandfield@dental.ufl.edu
Brady
L J
LJ
Progulske-Fox
A
A
Hillman
J D
JD
D000942:Antigens, Bacterial / Q000235:genetics / Q000378:metabolism; D001419:Bacteria / Q000235:genetics* / Q000472:pathogenicity*; D001424:Bacterial Infections / Q000382:microbiology* / Q000473:pathology; D020869:Gene Expression Profiling / Q000379:methods*; D005798:Genes, Bacterial; D006801:Humans; D014774:Virulence / Q000235:genetics
D000942:Antigens, Bacterial