title: [The MDR gene and cellular sensitivity to various effects].
abstract: mdr-Transfected K-562 cells revealed a relatively high resistance to cytotoxic monokines and ionizing radiation as compared to parental cells. Taken together with what is known about the resistance of mdr-expressing cells to multiple cytotoxic drugs, our results point to malignant cells having universal mechanisms of chemo-, bio- and radioresistance.
authors.affiliation: N.N. Petrov Research Institute of Oncology, Ministry of Health of the RF, St. Petersburg.
authors.forename: S G
authors.initials: SG
authors.lastname: Zubova
authors.forename: A O
authors.initials: AO
authors.lastname: Danilov
authors.forename: A I
authors.initials: AI
authors.lastname: Myshkov
authors.forename: T V
authors.initials: TV
authors.lastname: Bykova
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Zaritskiĭ
authors.forename: V B
authors.initials: VB
authors.lastname: Okulov
mesh_terms: D002455:Cell Division / Q000187:drug effects / Q000528:radiation effects; D005720:Gamma Rays; D019450:Genes, MDR; D006801:Humans; D020014:K562 Cells / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D008264:Macrophages / Q000187:drug effects / Q000528:radiation effects; D015846:Monokines / Q000378:metabolism*; D011839:Radiation, Ionizing; D011878:Radiotherapy / Q000379:methods; D014162:Transfection
chemical_list: D015846:Monokines
vernacular_title: Gen mdr i chuvstvitel'nost' kletok k razlichnym vozdeĭstviiam.