Comparison of persistent organic pollutant residues in serum and adipose tissue in a female population in Belgium, 1996-1998.
This study was performed to determine and compare persistent organic pollutant (POP) levels in different matrices in a female population. A total of 96 serum and 46 adipose tissue samples were collected from infertile women (n = 101) attending Centers for Reproductive Medicine in Belgium from 1996 to 1998. Gas chromatography with electron-capture detection was used to quantify residue levels on a lipid basis of seven organochlorine pesticides (OCPs) and seven polychlorinated biphenyls (PCBs). There was a strong association between adipose tissue and serum residues. The adipose tissue levels of CB-138, 153, 180 and p,p'-DDE were explained by the serum residues. Besides, the accumulation pattern for CB-153 and CB-180 in serum and adipose tissue are mirror images of each other.
Pauwels
A
A
Antwerp University, Toxicological Center (Pharmaceutical Sciences), Universiteitsplein 1, B-2610 Wilrijk, Belgium.
Covaci
A
A
Weyler
J
J
Delbeke
L
L
Dhont
M
M
De Sutter
P
P
D'Hooghe
T
T
Schepens
P J
PJ
D000273:Adipose Tissue / Q000378:metabolism*; D000328:Adult; D001530:Belgium; D002849:Chromatography, Gas; D004784:Environmental Monitoring / Q000706:statistics & numerical data; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D006801:Humans; D007246:Infertility / Q000097:blood; D007306:Insecticides / Q000097:blood*; D008055:Lipids / Q000032:analysis; D011078:Polychlorinated Biphenyls / Q000097:blood*
D004785:Environmental Pollutants; D007306:Insecticides; D008055:Lipids; D011078:Polychlorinated Biphenyls