Surface changes of the erythrocytes membrane in alcoholics--a study of lectin binding.
Erythrocytes from 30 alcoholic patients as well as age and sex matched healthy control were examined, for hemagglutination titre, against, a purified galactose specific lectin from the latex of Pedilanthus tithymalodies. Mean hemagglutinin titre was significantly elevated (P < 0.001) in alcoholics as compared to controls. The results indicate that alcohol abuse is associated with adoptive cell surface changes on erythrocytes, measurable by its lectin binding capacity.
Nagda
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Department of Biochemistry, Dr. V. M. Medical College, Solapur.
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D000328:Adult; D000437:Alcoholism / Q000097:blood*; D016022:Case-Control Studies; D004903:Erythrocyte Aggregation; D004910:Erythrocyte Membrane / Q000378:metabolism*; D006801:Humans; D037102:Lectins / Q000097:blood*; D008297:Male; D008875:Middle Aged
D037102:Lectins