Fluoride profiles in dental plaque in vivo formed on fluoride pre-treated human enamel.
Using a novel device capable of generating plaque in vivo on a natural enamel substrate, it has been possible to determine fluoride profiles from the saliva-plaque interface towards the enamel surface. Fluoride profiles in dental plaques tended to fall from the saliva-plaque interface towards the enamel. The device also offered the possibility of examining fluoride distributions after pre-treatment of the enamel with fluoride in vitro. Fluoride profiles were determined in plaque generated in vivo on enamel surfaces, which had been previously treated with a 900-ppm fluoride solution. The results showed the previously reported fall from the plaque surface, but in addition, a further rise towards the enamel surface was seen. The data imply that enamel loaded with fluoride can release some of this fluoride back into the plaque and may act as a fluoride reservoir.
Arai
K
K
Department of Preventive Dentistry and Dental Public Health, School of Dentistry, Aichi-Gakuin University, Nagoya, Japan. arai@dpc.aichi-gakuin.ac.jp
Kato
K
K
Nakagaki
H
H
Toyama
A
A
Nagai
N
N
Noguchi
T
T
Kirkham
J
J
Robinson
C
C
Thuy
T T
TT
Ha
N T
NT
D002118:Calcium / Q000032:analysis; D002327:Cariostatic Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics; D003743:Dental Enamel / Q000378:metabolism*; D003773:Dental Plaque / Q000737:chemistry / Q000188:drug therapy*; D005459:Fluorides / Q000008:administration & dosage* / Q000493:pharmacokinetics; D006801:Humans; D010710:Phosphates / Q000032:analysis; D014089:Tooth Remineralization / Q000379:methods*
D002327:Cariostatic Agents; D010710:Phosphates; D005459:Fluorides; D002118:Calcium