Metastatic complete hydatidiform mole with a surviving coexistent twin. A case report.
BACKGROUND
Complete hydatidiform molar pregnancy with a coexistent live fetus is a rare clinical entity with poor fetal survival and an uncertain maternal risk.


METHODS
A twin gestation consisting of a complete molar pregnancy as one twin and a normal second "twin" was identified in the second trimester. The patient was managed expectantly until 28 weeks' gestation, at which time evidence of metastatic trophoblastic disease was identified. She delivered a healthy infant by cesarean section and received postoperative single-agent chemotherapy. She was disease free six months after treatment.


CONCLUSIONS
Patients with documented complete molar pregnancies and coexistent live fetuses present several complex clinical issues. Though successful in some instances, expectant management should be used with caution in these patients.
Kauffman
D E
DE
Department of Obstetrics and Gynecology, Magee-Womens Hospital, Pittsburgh, Pennsylvania 15206, USA.
Sutkin
G
G
Heine
R P
RP
Watt-Morse
M
M
Price
F V
FV
D000328:Adult; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000473:pathology / Q000628:therapy*; D007231:Infant, Newborn; D008175:Lung Neoplasms / Q000556:secondary / Q000628:therapy; D008297:Male; D011247:Pregnancy; D011272:Pregnancy, Multiple; D014427:Twins; D014594:Uterine Neoplasms / Q000473:pathology / Q000628:therapy*
D018997:Chorionic Gonadotropin, beta Subunit, Human