[Excitatory amino acid antagonists and potentiation of cortical evoked potentials].
Changes of evoked potentials under the influence of NBQX (a non-NMDA receptor antagonist), MK-801 (a NMDA receptor antagonist) and GDEE (a nonselective antagonist of glutamate receptor) were studied. GDEE augmented potentiation and was marked progression of potentiation with increasing number of stimuli. There was no potentiation of responses in relation to the number of stimulus in a series in experiments with both MK-801 and NBQX. Interpretation of results with NBQX and MK-801 is difficult.
Nanka
O
O
Fyziologický ústav AV CR a Anatomický ústav 1. lékarské fakulty Univerzity Karlovy, Praha, Czech Republic. Ondrej.Nanka@lf1.cuni.cz
D000818:Animals; D016291:Dizocilpine Maleate / Q000494:pharmacology; D005071:Evoked Potentials / Q000187:drug effects*; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology*; D005971:Glutamates; D008297:Male; D011810:Quinoxalines / Q000494:pharmacology; D051381:Rats; D018091:Receptors, AMPA / Q000037:antagonists & inhibitors
D018691:Excitatory Amino Acid Antagonists; D005971:Glutamates; D011810:Quinoxalines; D018091:Receptors, AMPA; C062865:2,3-dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline; C011829:glutamic acid diethyl ester; D016291:Dizocilpine Maleate
Antagonisté excitacních aminokyselin a potenciace korových evokovaných potenciálů.