title: Evaluation of quality of life in patients with malignant dysphagia.
abstract: BACKGROUND
  In the last 10 years of clinical research there has been increasing interest in the evaluation of quality of life. Several generic and specific instruments have been developed for this purpose. EORTC QLQ C-30 is a cancer-specific questionnaire translated into various languages and validated in several European countries including Italy, where the impact of malignant disease on different areas of quality of life is poorly documented.
  
  
  METHODS
  The EORTC QLQ C-30 was administered to 109 patients referred to the endoscopy division of the Istituto Nazionale Tumori, Milan, for endoscopic palliative treatment of malignant dysphagia to test its characteristics in terms of acceptability and clinical validity.
  
  
  RESULTS
  In this group of patients the impact of advanced esophageal cancer was highly evident for Emotional and Physical Functioning, Fatigue and Global QoL scales. Dysphagia is a serious problem for many patients; there is a correlation between grade of dysphagia and four QoL dimensions.
  
  
  CONCLUSIONS
  QoL assessment is an important tool to evaluate the adequate management of patients with esophageal cancer. The EORTC QLQ-C30 questionnaire proved to be valid and reliable also in this population.
authors.affiliation: Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy. Psicologia@istitutotumori.mi.it
authors.forename: C
authors.initials: C
authors.lastname: Brunelli
authors.forename: P
authors.initials: P
authors.lastname: Mosconi
authors.forename: P
authors.initials: P
authors.lastname: Boeri
authors.forename: L
authors.initials: L
authors.lastname: Gangeri
authors.forename: P
authors.initials: P
authors.lastname: Pizzetti
authors.forename: F
authors.initials: F
authors.lastname: Cerrai
authors.forename: A
authors.initials: A
authors.lastname: Schicchi
authors.forename: G
authors.initials: G
authors.lastname: Apolone
authors.forename: M
authors.initials: M
authors.lastname: Tamburini
mesh_terms: D000368:Aged; D003680:Deglutition Disorders / Q000209:etiology* / Q000523:psychology*; D004938:Esophageal Neoplasms / Q000150:complications* / Q000523:psychology*; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires