title: Acrokeratosis paraneoplastica (Bazex syndrome) with adenocarcinoma of the colon: report of a case and review of the literature.
abstract: Acrokeratosis paraneoplastica is a rare disease and is uncommon even in patients with upper aerodigestive tract cancer. We report a 63-year-old man with a 1-month history of numerous pruritic lesions and vesicles on both feet. Although he had received local therapy, progressive dense scale formation involving both palms and both soles was found. Colonoscopy was performed because of hematochezia, and it revealed an early colon cancer. After the resection of the cancer, the skin lesions began to fall off dramatically. To the best of our knowledge, there is no report of acrokeratosis paraneoplastica associated with colon cancer in the literature. This is the first case report of acrokeratosis paraneoplastica associated with early colon cancer.
authors.affiliation: Department of Internal Medicine, Taipei Municipal Wan-Fang Hospital, Taiwan.
authors.forename: Y S
authors.initials: YS
authors.lastname: Hsu
authors.forename: G S
authors.initials: GS
authors.lastname: Lien
authors.forename: H H
authors.initials: HH
authors.lastname: Lai
authors.forename: Y S
authors.initials: YS
authors.lastname: Cheng
authors.forename: C H
authors.initials: CH
authors.lastname: Hu
authors.forename: M C
authors.initials: MC
authors.lastname: Hsieh
authors.forename: C L
authors.initials: CL
authors.lastname: Fang
authors.forename: S
authors.initials: S
authors.lastname: Pan
mesh_terms: D000169:Acrodermatitis / Q000150:complications*; D000230:Adenocarcinoma / Q000150:complications*; D003110:Colonic Neoplasms / Q000150:complications*; D006801:Humans; D007642:Keratosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000150:complications* / Q000453:epidemiology