Spread of methicillin-resistant Staphylococcus aureus belonging to the Brazilian epidemic clone in a general hospital and emergence of heterogenous resistance to glycopeptide antibiotics among these isolates.
Methicillin-resistant Staphylococcus aureus (MRSA) infections have been increasing at an alarming rate world-wide. MRSA epidemics due to the clonal spread of multi-resistant isolates have been described. In this paper we show the absolute predominance of MRSA strains from the Brazilian epidemic clone in a hospital in the Northeast region of Brazil and the emergence of a vancomycin and teicoplanin heterogeneous resistant subpopulation among these isolates.
dos Santos Soares
M J
MJ
Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Prof. Paulo de Góes, Laboratorio de Biologia Molecular de Bacterias, CCS, Bloco I, Cidade Universitária, Rio de Janeiro, RJ, Brazil.
da Silva-Carvalho
M C
MC
Ferreira-Carvalho
B T
BT
Figueiredo
A M
AM
D001938:Brazil / Q000453:epidemiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control; D004196:Disease Outbreaks / Q000517:prevention & control*; D018432:Drug Resistance, Multiple; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006801:Humans; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D011110:Polymorphism, Genetic; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control; D013211:Staphylococcus aureus / Q000145:classification / Q000187:drug effects* / Q000235:genetics