title: The influence of the type of anaesthesia on postoperative pain after kidney transplantation.
abstract: The postoperative pain treatment is one of important factors of a successful outcome after kidney transplantation. Improperly controlled pain leads to agitation, tachycardia, hypertension and increases risk of respiratory complications. Many studies have demonstrated good analgetic effect of morphine delivered by the method of patient controlled analgesia (PCA). Because the intensity of postoperative pain in end-stage kidney insufficiency patients can be modified by the type of received anaesthesia, it was decided to analyze the influence of standardized general anaesthesia on postoperative morphine consumption. 140 (ASA III) patients scheduled for kidney transplantation were included. Patients were divided into four groups; group K (control)--anaesthetised with fentanyl and N2O, group 1--fentanyl, N2O plus halothane, group 2--fentanyl, N2O plus propofol, group 3--fentanyl, N2O plus isoflurane. After operation and initial loading dose, PCA infusion of morphine was started. Bolus doses were set to 30 ug/kg, and lockout interval 10 min. Our results suggest that observed greater morphine consumption after GA with the use of propofol is connected with better psychomotor functions. In that group patients were better oriented and more efficiently controlled the PCA pump and pain.
authors.affiliation: Dept. of Anaesthesiology, The Medical University of Warsaw, Poland.
authors.forename: T
authors.initials: T
authors.lastname: Lazowski
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016058:Analgesia, Patient-Controlled; D000758:Anesthesia / Q000379:methods*; D005283:Fentanyl; D006221:Halothane; D006801:Humans; D007530:Isoflurane; D016030:Kidney Transplantation; D008875:Middle Aged; D009020:Morphine / Q000627:therapeutic use; D009609:Nitrous Oxide; D010149:Postoperative Pain / Q000188:drug therapy; D015742:Propofol
chemical_list: D009020:Morphine; D007530:Isoflurane; D009609:Nitrous Oxide; D005283:Fentanyl; D006221:Halothane; D015742:Propofol