[Acute renal failure after polyvalent immunoglobulin therapy].
BACKGROUND
Acute renal failure can be induced by intravenous administration of immunoglobulins, especially in patients with a predisposition for nephrotoxicity. The onset and resolution of acute renal failure is typically rapid, but in some cases hemodialysis may be needed.


METHODS
We present 2 cases of acute renal failure associated with intravenous immunoglobulin therapy: a 76-year-old man with a history of non-insulin-dependent diabetes mellitus and hypertension and a 77-year-old woman using nonsteroidal antiinflammatory drugs.


CONCLUSIONS
Intravenous immunoglobulins must be used with precaution in patients with risk factors for acute renal failure. In such patients, renal failure may be avoided by using preparations without sucrose.
Dilhuydy
M S
MS
Service de Néphrologie et d'Hémodialyse, CHU Pellegrin, Bordeaux.
Delclaux
C
C
De Precigout
V
V
Haramburu
F
F
Roger
I
I
Deminière
C
C
Mercié
P
P
Pellegrin
J L
JL
Aparicio
M
M
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000175:diagnosis; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000175:diagnosis; D003928:Diabetic Nephropathies / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D007116:Immunization, Passive / Q000009:adverse effects*; D007677:Kidney Function Tests; D008297:Male; D009220:Myositis / Q000188:drug therapy*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000188:drug therapy*; D012307:Risk Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal
Inuffisance rénale aiguë après cure d'immunoglobulines polyvalentes.