title: Adult rhabdomyoma: report of two cases of rhabdomyoma of the lip and of the eyelid.
abstract: We describe two cases of adult rhabdomyoma. One was located in the lip of a 66-year-old woman and was removed because it was clinically suspicious for infiltrating carcinoma. The other arose in the eyelid of a 60-year-old woman with a glass eye and was initially interpreted as a reactive process due to the prosthesis. Both lesions were composed of cells with oval nuclei and deeply eosinophilic cytoplasms with occasional cross striations. Immunoreactivity for desmin and myoglobin excluded the diagnosis of other tumors with similar morphology. The unusual association of the eyelid tumor with the prosthesis suggests a role for chronic irritation in the pathogenesis of rhabdomyoma.
authors.affiliation: Department of Dermatology, University of Ancona, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Verdolini
authors.forename: G
authors.initials: G
authors.lastname: Goteri
authors.forename: D
authors.initials: D
authors.lastname: Brancorsini
authors.forename: G
authors.initials: G
authors.lastname: Collina
authors.forename: O
authors.initials: O
authors.lastname: Simonetti
authors.forename: A
authors.initials: A
authors.lastname: Offidani
authors.forename: M
authors.initials: M
authors.lastname: Giangiacomi
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D005142:Eyelid Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008048:Lip Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000032:analysis; D012207:Rhabdomyoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins