title: SPECT bone scintigraphy in the diagnosis and management of mandibular condylar hyperplasia.
abstract: Isotope bone scans have been used for a number of years to assess growth activity in the mandibular condyle in patients who present with facial asymmetry. The aim is to distinguish normal bone growth within the condyle from increased activity that may be the cause of the asymmetry. Previous studies have, however, relied only on planar images. SPECT (single photon emission computed tomography) has been used with quantitative assessments of one mandibular condyle to clivus or lumbar spine, but we have compared one condyle with the other, which is more sensitive and accurate in detecting abnormal activity. A relative percentage uptake of 55% or more in the affected mandibular condyle is considered to be abnormal, and this has been validated by comparison with an age-matched control group. We have used SPECT as an aid to diagnosis and treatment in 18 patients with asymmetrical growth and have constructed a therapeutic algorithm to aid the treatment of these patients.
authors.affiliation: Oral and Maxillofacial, Morriston Hospital, Swansea, UK.
authors.forename: S C
authors.initials: SC
authors.lastname: Hodder
authors.forename: J I
authors.initials: JI
authors.lastname: Rees
authors.forename: T B
authors.initials: TB
authors.lastname: Oliver
authors.forename: P E
authors.initials: PE
authors.lastname: Facey
authors.forename: A W
authors.initials: AW
authors.lastname: Sugar
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D003388:Cranial Fossa, Posterior / Q000000981:diagnostic imaging; D005146:Facial Asymmetry / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006965:Hyperplasia; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008297:Male; D008310:Malocclusion / Q000209:etiology / Q000601:surgery; D008335:Mandibular Condyle / Q000000981:diagnostic imaging* / Q000254:growth & development / Q000473:pathology / Q000601:surgery; D010027:Osteotomy; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D013669:Technetium Tc 99m Medronate; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate