Endogenous retroviruses and multiple sclerosis.
Endogenous retroviruses are normal constituents in vertebrate genomes. They have been associated with various diseases of presumed autoimmune etiology. However, conclusive evidence of their significance as susceptibility factors in these diseases is still lacking. In our laboratory we have focused attention upon endogenous retroviruses as candidate genes in multiple sclerosis. In this communication we describe general properties of endogenous retroviruses and we present observations from some of our studies.
Rasmussen
H B
HB
Department of Life Science and Chemistry, Roskilde University, P.O. Box 260, DK-4000 Roskilde, Denmark.
Lucotte
G
G
Clausen
J
J
D020077:Endogenous Retroviruses / Q000235:genetics* / Q000276:immunology*; D005814:Genes, Viral / Q000276:immunology; D006801:Humans; D009103:Multiple Sclerosis / Q000276:immunology* / Q000821:virology*