title: Absorption of calcium, magnesium, phosphorus, iron and zinc in growing male rats fed diets containing either phytate-free soybean protein or soybean protein isolate or casein.
abstract: The effect of dietary phytate-free soybean protein (PFS) on intestinal mineral absorption and retention was examined in growing male rats using a three-day mineral balance technique. The rats were fed diets containing PFS, soybean protein isolate (SPI) or casein at a 20% level for 5 wk. Total calcium (Ca), magnesium (Mg), phosphorus (P), iron (Fe) and zinc (Zn) contents in diets were adjusted to 0.35, 0.05, 0.7, 0.0035 and 0.003%, respectively, by supplementation of the diet with their salts. Mineral absorption and retention ratios in rats fed the PFS diet were significantly higher than those in rats fed either the SPI or casein diet. These results suggest that PFS may be a promising dietary protein source for improving the mineral bioavailability in humans.
authors.affiliation: Department of Hygienic Sciences, Kobe Pharmaceutical University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kamao
authors.forename: N
authors.initials: N
authors.lastname: Tsugawa
authors.forename: K
authors.initials: K
authors.lastname: Nakagawa
authors.forename: Y
authors.initials: Y
authors.lastname: Kawamoto
authors.forename: K
authors.initials: K
authors.lastname: Fukui
authors.forename: K
authors.initials: K
authors.lastname: Takamatsu
authors.forename: G
authors.initials: G
authors.lastname: Kuwata
authors.forename: M
authors.initials: M
authors.lastname: Imai
authors.forename: T
authors.initials: T
authors.lastname: Okano
mesh_terms: D000818:Animals; D015519:Bone Density / Q000502:physiology; D002136:Calcium, Dietary / Q000493:pharmacokinetics; D002364:Caseins / Q000008:administration & dosage* / Q000378:metabolism / Q000494:pharmacology; D004032:Diet; D004044:Dietary Proteins / Q000378:metabolism* / Q000494:pharmacology; D007408:Intestinal Absorption / Q000187:drug effects*; D019266:Iron, Dietary / Q000493:pharmacokinetics; D008274:Magnesium / Q000493:pharmacokinetics; D008297:Male; D008903:Minerals / Q000493:pharmacokinetics*; D016226:Phosphorus, Dietary / Q000493:pharmacokinetics; D010833:Phytic Acid; D051381:Rats; D017208:Rats, Wistar; D030262:Soybean Proteins / Q000008:administration & dosage* / Q000378:metabolism / Q000494:pharmacology; D015032:Zinc / Q000493:pharmacokinetics
chemical_list: D002136:Calcium, Dietary; D002364:Caseins; D004044:Dietary Proteins; D019266:Iron, Dietary; D008903:Minerals; D016226:Phosphorus, Dietary; D030262:Soybean Proteins; D010833:Phytic Acid; D008274:Magnesium; D015032:Zinc