[The significance of detecting medium-weight molecules in the plasma of patients with viral and bacterial infectious].
The content of medium-weight molecules (MWM) in the plasma was evaluated by the screening method in 280 patients with prevalent infectious diseases (viral hepatitides A, B, and C, influenza, acute dysentery, alimentary toxicoinfections, and tonsillitis). Control group consisted of 70 donors. The maximum levels of MWM were observed at the peak of disease. In viral infections the increase in the level of MWM was longer. The values of MWM depended on the disease severity and presence of the intoxication syndrome. Plasma concentration of MWM correlated with the presence of the leading clinical syndromes in infectious diseases. Measurement of MWM level in the plasma of infectious patients can be used as a criterion of recovery and a prognostic and additional diagnostic test.
Nagoev
B S
BS
Gabrilovich
M I
MI
D001424:Bacterial Infections / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology; D015415:Biomarkers; D001798:Blood Proteins / Q000032:analysis*; D006801:Humans; D014777:Virus Diseases / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology
D015415:Biomarkers; D001798:Blood Proteins
Znachenie opredeleniia srednikh molekul v plazme krovi pri infektsionnykh zabolevaniiakh virusnoĭ i bakterial'noĭ étiologii.