title: Neuromotor microalterations in subjects with spasmophilia symptoms: a preliminary study.
abstract: Spasmophilia is a relatively unknown condition characterized by perturbations of the neuromuscular system. We hypothesized that spasmophilia may negatively affect neuromotor functions in subtle ways. Three tests including tremor, rapid pointing movements, and alternating movements were quantified in a group of subjects with spasmophilia symptoms (SS) (n = 10) and a healthy control group (n = 10). Most of the characteristics used to evaluate motor functions in these three tests revealed no significant differences between the two groups except for two characteristics in alternating movements and two characteristics in rapid pointing movements. In terms of variances, a dissociation between voluntary movements and involuntary movements was observed for the two groups. Control subjects had significantly higher variances in involuntary movements such as tremor, while subjects with SS had significantly higher variances in voluntary movements such as alternating and rapid pointing movements. A significant increase in asymmetry in hand laterality was also noted for some characteristics in subjects with SS.
authors.affiliation: Cognitive Neuroscience Laboratory, University of Quebec at Montreal, Canada.
authors.forename: C
authors.initials: C
authors.lastname: Després
authors.forename: A
authors.initials: A
authors.lastname: Beuter
authors.forename: R
authors.initials: R
authors.lastname: Vadeboncoeur
authors.forename: A
authors.initials: A
authors.lastname: de Geoffroy
mesh_terms: D006801:Humans; D012720:Severity of Illness Index; D013746:Tetany / Q000150:complications*; D013997:Time Factors; D014202:Tremor / Q000175:diagnosis* / Q000209:etiology*