title: Acute effects of tumor necrosis factor-alpha on testicular germ cell apoptosis and vascular neutrophil adhesion in rats.
abstract: Acute effects of tumor necrosis factor-alpha (TNF-alpha) on testicular germ cell apoptosis and vascular neutrophil adhesion were investigated in rats. Acute administration of TNF-alpha did not show a significant increase in percentage of apoptotic tubules and apoptotic germ cells. TNF-alpha administration did not enhance neutrophil adhesion score in the intertubular and subtunical vein. TNF-alpha does not acutely influence testicular germ cell apoptosis and vascular neutrophil adhesion in rats.
authors.affiliation: Department of Urology, Yamagata University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yazawa
authors.forename: I
authors.initials: I
authors.lastname: Sasagawa
authors.forename: T
authors.initials: T
authors.lastname: Nakada
mesh_terms: D000728:Androgens / Q000378:metabolism; D000818:Animals; D017209:Apoptosis / Q000187:drug effects*; D002448:Cell Adhesion / Q000187:drug effects*; D005938:Glucocorticoids / Q000378:metabolism; D008297:Male; D051381:Rats; D017382:Reactive Oxygen Species; D013094:Spermatozoa / Q000187:drug effects*; D013737:Testis / Q000166:cytology / Q000187:drug effects*; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology*; D014680:Veins / Q000166:cytology*
chemical_list: D000728:Androgens; D005938:Glucocorticoids; D017382:Reactive Oxygen Species; D014409:Tumor Necrosis Factor-alpha