[Human gastrointestinal tract mucins encoded by the MUC gene family].
Epithelial mucins, MUC gene products, are widely expressed in human organs such as airways, the urogenital and gastrointestinal tracts, and the eyes. MUC-type mucins have very large sizes and complex structures with very extensive O-glycosylation and are regarded as protective molecules. The aim of this review is to discuss mucin glycoproteins structure, biosynthesis and functions in normal and pathologically altered epithelial mucosa of human gastrointestinal tract.
Paszkiewicz-Gadek
A
A
Zakład Chemii Ogólnej i Organicznej Akademii Medycznej w Białymstoku.
Porowska
H
H
D004064:Digestive System / Q000503:physiopathology; D004068:Digestive System Physiological Phenomena; D005753:Gastric Mucosa / Q000378:metabolism*; D006801:Humans; D018396:Mucin-1 / Q000378:metabolism; D055262:Mucin-2; D055263:Mucin-3; D055272:Mucin-6; D009077:Mucins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D010446:Peptide Fragments / Q000378:metabolism
C116055:MUC1 tandem repeat peptide; C524625:MUC2 protein, human; C524734:MUC6 protein, human; D018396:Mucin-1; D055262:Mucin-2; D055263:Mucin-3; D055272:Mucin-6; D009077:Mucins; D010446:Peptide Fragments
Mucyny ludzkie przewodu pokarmowego jako produkty genów MUC.