title: A comparative analysis of latex allergy in the healthy versus high-risk pediatric population.
abstract: Allergic or hypersensitivity reactions to natural latex have been reported with increasing frequency. Many specific populations have been identified as high risk for latex sensitivity. This research focused on the pediatric surgical population. Previous research had identified children with spina bifida, children requiring bowel or bladder programs, children with a history of atopy, and children with multiple surgical exposures as high risk. The purposes of this study were to identify the prevalence of latex sensitivity in the healthy pediatric population, to compare the incidence with that of an identified high-risk population, and to determine if a survey of known risk factors for latex sensitivity was predictive of positive serum latex antibody. This was a prospective, descriptive correlational study utilizing a convenience sample size of 400 pediatric patients aged 1 to 18 years, conducted at Henry Ford Hospital and Children's Hospital of Michigan. Children were identified as high or low risk from the survey results, and all had AlaSTAT latex allergy testing (Diagnostic Products Corporation, Los Angeles, Calif). The survey was not predictive for the positive serum latex antibody. The incidence of latex sensitivity was found to be greater in the high-risk group (17.3%) than in the general pediatric population (8.6%) using the chi 2 test (P = .01). Latex-reduced environments for children likely to have repeated latex exposure may decrease the risk of reaction and more importantly decrease sensitization for them. From an anesthetic standpoint, a fairly standard preoperative question is, "What are the number and types of surgeries a patient has undergone in the past?" This information can alert the healthcare worker to how much exposure the child has had and whether a latex-reduced environment might be required to avert a latex reaction.
authors.affiliation: Henry Ford Hospital/University of Detroit Mercy Graduate Program of Nurse Anesthesia, USA.
authors.forename: K
authors.initials: K
authors.lastname: Faust
authors.forename: C
authors.initials: C
authors.lastname: Shrewsbury
authors.forename: K
authors.initials: K
authors.lastname: Zaglaniczny
authors.forename: M
authors.initials: M
authors.lastname: Jarrett
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis; D005260:Female; D006776:Hospitals, Pediatric; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000150:complications; D015994:Incidence; D007223:Infant; D020315:Latex Hypersensitivity / Q000453:epidemiology* / Q000209:etiology*; D008297:Male; D008824:Michigan / Q000453:epidemiology; D011237:Predictive Value of Tests; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D016135:Spinal Dysraphism / Q000150:complications / Q000601:surgery; D013514:Surgical Procedures, Operative / Q000009:adverse effects / Q000706:statistics & numerical data