title: Microtubule-associated protein MAP2 preferentially binds to a dA/dT sequence present in mouse satellite DNA.
abstract: Microtubule-associated protein MAP2 binds to the Sau96.1 restriction monomer fragment of mouse satellite DNA. This fragment is also present in a lower proportion in bulk DNA. The digestion of MAP2-Sau96.1 fragment complex by DNase results in the protection of certain nucleotide sequences. The sequence poly(dA)4/poly(dT)4 is mainly protected against DNase digestion.
authors.affiliation: Centro de Biologia Molecular (CSIC-UAM), Universidad Autónoma de Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Avila
authors.forename: E
authors.initials: E
authors.lastname: Montejo de Garcini
authors.forename: F
authors.initials: F
authors.lastname: Wandosell
authors.forename: A
authors.initials: A
authors.lastname: Villasante
authors.forename: J M
authors.initials: JM
authors.lastname: Sogo
authors.forename: N
authors.initials: N
authors.lastname: Villanueva
mesh_terms: D016475:3T3 Cells; D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D004276:DNA, Satellite / Q000378:metabolism*; D015252:Deoxyribonucleases, Type II Site-Specific; D051379:Mice; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D008969:Molecular Sequence Data; D011089:Polydeoxyribonucleotides / Q000378:metabolism*; D013552:Swine
chemical_list: D004276:DNA, Satellite; D008869:Microtubule-Associated Proteins; D011089:Polydeoxyribonucleotides; C084838:polydeoxyadenylic acid-polythymidylic acid; D015252:Deoxyribonucleases, Type II Site-Specific; C024405:GATC-specific type II deoxyribonucleases