Combined ECT and clozapine in treatment-resistant mania.
A treatment-resistant manic patient failed to respond to conventional treatment, adjunctive olanzapine (20 mg/day), clozapine (600 mg/day), or ECT alone, but did respond to ECT combined with low dose clozapine (200 mg/day). Maintenance ECT combined with clozapine resulted in a remission over the 18-month period.
Chanpattana
W
W
Department of Psychiatry, Srinakharinwirot University, Bangkok, Thailand.
D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D001714:Bipolar Disorder / Q000628:therapy*; D003024:Clozapine / Q000008:administration & dosage* / Q000009:adverse effects; D003131:Combined Modality Therapy; D004565:Electroconvulsive Therapy; D006801:Humans; D008134:Long-Term Care; D008297:Male
D014150:Antipsychotic Agents; D003024:Clozapine