title: Oligodendrocytic gliomatosis cerebri.
abstract: We describe a very unusual case of gliomatosis cerebri (GC) with oligodendrocytic differentiation. A 65-year-old man presented with a convulsive seizure. Magnetic resonance (MR) documented diffuse enlargement of cerebral hemispheres, brainstem, and right cerebellar hemisphere. After admission, the patient manifested a progressive deterioration of his neurological condition. A right temporal craniotomy and temporal lobectomy were performed to obtain brain decompression and diagnosis. Pathological findings were those of a GC consisting of neoplastic oligodendrocytes. Oligodendrocytic GC is a very rare pathological condition. Diagnosis of GC is usually made at autopsy. Our case confirms that diagnosis by a combination of MR imaging and brain biopsy.
authors.affiliation: Department of Neurological Sciences, S. Maria Hospital, Terni, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Tancredi
authors.forename: A
authors.initials: A
authors.lastname: Mangiola
authors.forename: A
authors.initials: A
authors.lastname: Guiducci
authors.forename: A
authors.initials: A
authors.lastname: Peciarolo
authors.forename: P
authors.initials: P
authors.lastname: Ottaviano
mesh_terms: D000368:Aged; D001706:Biopsy; D001921:Brain / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D018302:Neoplasms, Neuroepithelial / Q000175:diagnosis / Q000473:pathology*; D009836:Oligodendroglia / Q000473:pathology*