title: Liver and brain mucormycosis in a diabetic patient type II successfully treated with liposomial amphotericin B.
abstract: A case of liver and brain mucormycosis in a 73-y-old diabetic patient is described. The patient presented with fever and a moderate, tender hepatomegaly and a C/T scan examination of the abdomen and brain showed multiple hepatic and cerebral nodular lesions. The largest of the liver lesions was aspirated and broad hyphae of mucor were demonstrated in the purulent material obtained. The patient was treated successfully (for 40 d) with intravenous liposomal amphotericin B and then with itraconazole for 3 months. To our knowledge, this is the first case of a diabetic patient with both liver and brain mucormycosis who has been treated successfully.
authors.affiliation: 5th Medical Department of Internal Medicine, Evangelismos Hospital, Athens, Greece.
authors.forename: G
authors.initials: G
authors.lastname: Tsaousis
authors.forename: A
authors.initials: A
authors.lastname: Koutsouri
authors.forename: C
authors.initials: C
authors.lastname: Gatsiou
authors.forename: O
authors.initials: O
authors.lastname: Paniara
authors.forename: C
authors.initials: C
authors.lastname: Peppas
authors.forename: G
authors.initials: G
authors.lastname: Chalevelakis
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D001927:Brain Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D009091:Mucormycosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D009894:Opportunistic Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B