title: Spatial filtering methods for local activation determination in fractionated electrograms from simulated infarcted hearts.
abstract: The purpose of this work is the enhancement of local activation in multiphasic extracellular recordings coming from infarcted myocardial tissue and, consequently, the distinction of local from distal activation. Deconvolution procedures are applied, in the form of spatial filtering, in order to estimate transmembrane currents from the extracellular recordings. Simulated data are used in order to test the methods. The current source estimates are compared to the actual transmembrane currents and to Laplacian estimates.
authors.affiliation: Aristotelian University, Lab of Medical Informatics, Medical School, Thessaloniki, Macedonia, Greece.
authors.forename: I
authors.initials: I
authors.lastname: Chouvarda
authors.forename: N
authors.initials: N
authors.lastname: Maglaveras
authors.forename: J
authors.initials: J
authors.lastname: de Bakker
authors.forename: F J
authors.initials: FJ
authors.lastname: van Capelle
authors.forename: C
authors.initials: C
authors.lastname: Pappas
mesh_terms: D003198:Computer Simulation; D004562:Electrocardiography; D006329:Heart Conduction System / Q000502:physiology; D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis / Q000503:physiopathology*; D012815:Signal Processing, Computer-Assisted