Ultrasonographic, axial, and peripheral measurements in female patients with benign hypermobility syndrome.
Twenty-five female Caucasians, aged 19-57 years, with the hypermobility syndrome had bone density measurements using established noninvasive techniques such as dual X-ray absorptiometry (DXA), single photon absorptiometry (SPA), heel ultrasound (US), and peripheral computed tomography (pQCT) acquisitions of the radius. As a group, comparisons of the different bone indices with the corresponding age-matched reference population resulted in normal z-scores for the arial densities, however, values for the volumetric total and cortical bone at the radius measured by pQCT were significantly lower than expected (P < 0.0001). Spinal and femoral bone density results were significant after correction for body mass index (BMI). This cross-sectional study shows that the benign hypermobility syndrome patients have lowered t-scores for data reflecting bone structure and bone strength as measured with US and the tomographic technique.
Nijs
J
J
Arthritis and Metabolic Bone Disease Research Unit, KU Leuven, UZ Pellenberg, Belgium.
Van Essche
E
E
De Munck
M
M
Dequeker
J
J
D015502:Absorptiometry, Photon / Q000379:methods; D000328:Adult; D015519:Bone Density; D005260:Female; D005272:Femur Neck / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007593:Joint Instability / Q000000981:diagnostic imaging* / Q000276:immunology / Q000503:physiopathology; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000503:physiopathology; D008875:Middle Aged; D011884:Radius / Q000000981:diagnostic imaging / Q000503:physiopathology; D014463:Ultrasonography