[Inflammatory abdominal aortic aneurysm. Role of corticosteroid therapy].
For more than 20 years it has been generally acknowledged that operation for inflammatory abdominal aortic aneurysm (IAAA) using the common in-lay-graft procedure will induce the regression of peri-aortic fibrosis. However in prospective studies, after a 2 years follow-up, no regression appeared in approximated 8% of the cases (table I). Moreover in some IAAA a corticosteroid treatment (CS) was prescribed and it produced a regression of fibrosis and therefore facilitated the operation. Nevertheless the usefulness of the CS remains debated. We report 4 new cases of IAAA with CS. Based on our cases and an analysis of the literature we conclude that when there is no urgency to operate (diameter inferior to 50 mm) CS is the best option in IAAA with either severe inflammation or ureter involvement. Due to the regression of the fibrosis it can facilitate the surgical procedure. However it needs to be conducted with an adequate dose and duration. Finally the CS is the only possibility when the inflammation persist following the treatment of the IAAA.
Testart
J
J
Clinique Chirurgicale, CHU de Rouen, Hôpital Charles Nicolle, 1, rue de Germont, 76031 Rouen Cedex, France.
Plissonnier
D
D
Peillon
C
C
Watelet
J
J
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D017544:Aortic Aneurysm, Abdominal / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery*; D001025:Aortitis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D005355:Fibrosis; D006801:Humans; D008297:Male; D008875:Middle Aged
D000305:Adrenal Cortex Hormones