[The role of environmental factors in the formation of kidney calculi].
Various endo- and exogenous factors play a role in the urinary stones formation tract. The aim of the study was to define the type and frequency of hyperexcretion of lithogenic substances in school children population and to determine an influence of risk factors on hyperexcretion of crystallizing substances. The study included 220 school children. Preurolithiasis state (PS) was found in 30% children. The most frequently hyperoxaluria, hyperuricosuria and hypercalciuria were diagnosed and it may be connected with abnormal nutritional habits, excessive application of multivitamins, vitamin D and calcium, disturbances in drinking water chemical composition (higher amount of calcium, smaller amount of magnesium, abnormal pH). Urinary tract infections, particularly in children with obstructive uropathy are an important risk factor in the examined population. Positive familial history of urolithiasis in 43.3% children may indicate for the important role of the genetic factor in the pathogenesis of the disease.
Jung
A
A
Kliniki Pediatrii i Nefrologii Dzieciecej CSK WAM w Warszawie.
Kamińska
A
A
Samol
B
B
Zuber
J
J
D000293:Adolescent; D002648:Child; D004777:Environment; D005260:Female; D006801:Humans; D008297:Male; D014545:Urinary Calculi / Q000209:etiology* / Q000235:genetics