A genetic analysis of cyromazine resistance in Drosophila melanogaster (Diptera: Drosophilidae).
Flies resistant to the insect growth regulator cyromazine were selected in the F1 generation from a cyromazine-susceptible strain of Drosophila melanogaster (Meigen) treated with ethyl methanesulfonate. Four resistant strains were isolated by screening with cyromazine at a concentration > LC100 of susceptibles. In each strain, resistance is conferred by a single gene mutation. Cyromazine resistance in two of the mutants (rst(1a)cyr1 and rst(1a)cyr2) localizes to map position 17 of the X chromosome. Evidence is presented that these mutations are alleles of the gene rst(1a)cyr. Cyromazine resistance in another of the mutants (Rst(1b)Cyr) is also X-linked, and localizes to map position 49 of the X chromosome. The location of the gene conferring cyromazine resistance in the other mutant (Rst(2b)Cyr) is map position 66 of chromosome II. This is possibly an allele of a previously characterized cyromazine resistance gene, Rst(2)Cyr. Dosage-mortality analyses demonstrate a low level of cyromazine resistance is conferred in all strains.
Daborn
P J
PJ
Department of Biology and Biochemistry, University of Bath, UK.
McKenzie
J A
JA
Batterham
P
P
D000818:Animals; D002874:Chromosome Mapping; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D017344:Genes, Insect; D007305:Insecticide Resistance / Q000235:genetics; D007306:Insecticides; D007605:Juvenile Hormones; D008297:Male; D009154:Mutation; D014227:Triazines; D014960:X Chromosome
D007306:Insecticides; D007605:Juvenile Hormones; D014227:Triazines; C028704:cyromazine