title: Beneficial effect of fluoxetine in a case of sporadic hyperekplexia.
abstract: We studied a 67-year-old woman with a sporadic form of hyperekplexia, who experienced 8-10 excessive startle responses to unexpected stimuli per month. Therapy with fluoxetine had a definite beneficial effect. This finding supports the hypothesis that serotonergic mechanisms play a role in this disorder.
authors.affiliation: Department of Neurology, University of Sassari, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Sechi
authors.forename: S
authors.initials: S
authors.lastname: Sotgiu
authors.forename: M P
authors.initials: MP
authors.lastname: Valenti
authors.forename: M G
authors.initials: MG
authors.lastname: Pitzolu
authors.forename: P
authors.initials: P
authors.lastname: Peterlongo
authors.forename: L
authors.initials: L
authors.lastname: Larizza
authors.forename: G
authors.initials: G
authors.lastname: Rosati
mesh_terms: D000368:Aged; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use*; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy* / Q000378:metabolism / Q000523:psychology; D013216:Reflex, Startle / Q000187:drug effects*; D012701:Serotonin / Q000502:physiology
chemical_list: D018687:Antidepressive Agents, Second-Generation; D005473:Fluoxetine; D012701:Serotonin