Solution-phase synthesis of diaryl selenides using polymer-supported borohydride.
[reaction: see text] A new series of selenium-containing diaryl retinoids have been prepared by a new direct nickel(II)-catalyzed coupling of a diselenide with an iodoaryl in the presence of polymer-supported borohydride.
Millois
C
C
GALDERMA R&D, Sophia-Antipolis, France.
Diaz
P
P
D001894:Borohydrides / Q000737:chemistry*; D009369:Neoplasms / Q000188:drug therapy; D016566:Organoselenium Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D011565:Psoriasis / Q000188:drug therapy; D018168:Receptors, Retinoic Acid / Q000819:agonists; D047488:Retinoid X Receptors; D012176:Retinoids / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D014157:Transcription Factors / Q000819:agonists
D001894:Borohydrides; D016566:Organoselenium Compounds; D011108:Polymers; D018168:Receptors, Retinoic Acid; D047488:Retinoid X Receptors; D012176:Retinoids; D014157:Transcription Factors