title: Primary cutaneous large B-cell lymphomas.
abstract: According to the European Organization for Research and Treatment of Cancer classification, primary cutaneous large B-cell lymphomas are subdivided into 2 groups: follicle center cell large B-cell lymphomas and large B-cell lymphomas of the leg. The first type predominantly affects middle-aged adults with an equal gender distribution and presents with lesions on the head and trunk. Histology shows proliferations of predominantly large cleaved cells. The prognosis is excellent, with a 5-year survival rate >90%. The second group predominantly affects elderly females. Histologically the lesions are composed of centroblasts and/or immunoblasts (large round cells). The prognosis is more unfavorable with a 5-year survival rate of 50%. Intravascular large B-cell lymphoma is still classified as a provisional entity.
authors.affiliation: Department of Pathology, Henri Mondor Hospital, Créteil, France.
authors.forename: J
authors.initials: J
authors.lastname: Wechsler
authors.forename: M
authors.initials: M
authors.lastname: Bagot
mesh_terms: D017677:Age Distribution; D014408:Biomarkers, Tumor; D005838:Genotype; D006801:Humans; D016130:Immunophenotyping; D016393:Lymphoma, B-Cell / Q000453:epidemiology / Q000473:pathology*; D011379:Prognosis; D017678:Sex Distribution; D012878:Skin Neoplasms / Q000453:epidemiology / Q000473:pathology*; D016019:Survival Analysis
chemical_list: D014408:Biomarkers, Tumor