title: [Multinodular goiter and parotid carcinoma : a new case of Cowden's disease].
abstract: Cowden's Disease is an autosomal dominant genodermatosis associated with abnormalities of the breast, thyroid gland, gastrointestinal tract. We describe a 23-year-old girl who was diagnosed with this disease when she consulted for evaluation of a multinodular goiter. Further investigations revealed breast lesions, gastric polyposis and parotid cancer. Recognizing Cowden's disease is important for prompt screening for malignancies. Skin lesions are markers of precancerous development.
authors.affiliation: Service de Médecine Interne et de Néphrologie, Monastir, Tunisie.
authors.forename: M
authors.initials: M
authors.lastname: Kacem
authors.forename: J
authors.initials: J
authors.lastname: Zili
authors.forename: A
authors.initials: A
authors.lastname: Zakhama
authors.forename: F
authors.initials: F
authors.lastname: Hadj Youssef
authors.forename: S
authors.initials: S
authors.lastname: Mahjoub
authors.forename: C
authors.initials: C
authors.lastname: Boubakri
authors.forename: M
authors.initials: M
authors.lastname: El May
mesh_terms: D000328:Adult; D001941:Breast Diseases / Q000150:complications / Q000175:diagnosis; D005260:Female; D006044:Goiter, Nodular / Q000150:complications*; D006223:Hamartoma Syndrome, Multiple / Q000175:diagnosis*; D006801:Humans; D006965:Hyperplasia; D008046:Lip; D009092:Mucous Membrane / Q000473:pathology; D010307:Parotid Neoplasms / Q000150:complications* / Q000175:diagnosis; D011127:Polyps / Q000150:complications / Q000175:diagnosis; D012867:Skin / Q000473:pathology; D013274:Stomach Neoplasms / Q000150:complications / Q000175:diagnosis