title: Mesial temporal sclerosis and temporal lobe epilepsy: MR imaging deformation-based segmentation of the hippocampus in five patients.
abstract: In five patients with mesial temporal sclerosis, the authors verified the precision and reproducibility of hippocampal segmentations with deformation-based magnetic resonance (MR) imaging. The overall percentage overlap between automated segmentations was 92.8% (SD, 3.5%), between manual segmentations was 73.1% (SD, 9.5%), and between automated and manual segmentations was 74.8% (SD, 10.3%). Deformation-based hippocampal segmentations provided a precise method of hippocampal volume measurement in this patient population.
authors.affiliation: Department of Neurology, Saint Louis University, 3635 Vista Ave, St Louis, MO 63110, USA. hoganr2@slu.edu
authors.forename: R E
authors.initials: RE
authors.lastname: Hogan
authors.forename: K E
authors.initials: KE
authors.lastname: Mark
authors.forename: L
authors.initials: L
authors.lastname: Wang
authors.forename: S
authors.initials: S
authors.lastname: Joshi
authors.forename: M I
authors.initials: MI
authors.lastname: Miller
authors.forename: R D
authors.initials: RD
authors.lastname: Bucholz
mesh_terms: D000328:Adult; D004833:Epilepsy, Temporal Lobe / Q000473:pathology*; D005260:Female; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D012598:Sclerosis; D013702:Temporal Lobe / Q000473:pathology*