Daily folate supplementation is adequate prophylaxis against methotrexate-induced nausea and vomiting and avoids the need for expensive anti-emetic prescription.
Lorenzi
A R
AR
Johnson
A H
AH
Gough
A
A
D000328:Adult; D000932:Antiemetics / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000009:adverse effects; D002986:Clinical Trials as Topic; D019587:Dietary Supplements; D005260:Female; D005492:Folic Acid / Q000627:therapeutic use*; D006801:Humans; D015201:Meta-Analysis as Topic; D008727:Methotrexate / Q000009:adverse effects; D009325:Nausea / Q000139:chemically induced / Q000517:prevention & control*; D014839:Vomiting / Q000139:chemically induced / Q000517:prevention & control*
D000932:Antiemetics; D018501:Antirheumatic Agents; D005492:Folic Acid; D008727:Methotrexate