The impact of media composition and petite mutation on the longevity of a polyploid brewing yeast strain.
Ageing in Saccharomyces cerevisiae is a finite phenomenon, determined by replicative, rather than chronological lifespan. Yeast physiological condition is known to influence industrial fermentation performance, however, until recently cellular senescence has not been considered as a brewing yeast stress factor. A polyploid lager yeast (BB11) and a brewery isolate, exhibiting petite mutation were analysed for longevity. It was observed that mitochondrial deficiency induced a reduction in lifespan. In addition, replicative capacity was perceived to be dependent on environmental conditions.
Powell
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School of Biological and Molecular Sciences, Oxford Brookes University, Oxford, UK.
Quain
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Smart
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D003470:Culture Media; D008928:Mitochondria / Q000235:genetics*; D009154:Mutation; D011123:Polyploidy; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000502:physiology*
D003470:Culture Media