title: Benign esophageal schwannoma: report of a case.
abstract: We report herein the case of an otherwise asymptomatic 62-year-old woman who was found to have an incidental esophageal lesion during endoscopic follow-up of an unrelated disorder. An esophageal submucosal tumor was diagnosed, and the patient was subsequently monitored on a regular yearly basis. As the diameter of the tumor doubled over a 4-year period, the possibility of a malignant lesion could not be excluded, and she was admitted to our hospital for further investigations. Esophagography, endoscopy, endoscopic ultrasonography, and computed tomography confirmed a submucosal tumor, 35 mm in length, in the thoracic midesophagus. A leiomyoma or leiomyosarcoma was suspected based on the known incidence of such tumors, and tumor enucleation was performed. Gross inspection revealed a solid tumor arising from the wall of the esophagus. Histopathologic examination showed intertwined bundles of spindle cells with spiral-like proliferation, and immunohistochemical studies were positive for S-100 protein, whereby a diagnosis of esophageal schwannoma was established. The patient experienced no postoperative complications, and her clinical course to date has been satisfactory. To date, 2 years 8 months after surgery, she has shown no sign of tumor recurrence and remains in good health.
authors.affiliation: Department of Surgery, School of Medicine, Kitasato University, Kanagawa, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Kobayashi
authors.forename: S
authors.initials: S
authors.lastname: Kikuchi
authors.forename: H
authors.initials: H
authors.lastname: Shimao
authors.forename: Y
authors.initials: Y
authors.lastname: Hiki
authors.forename: A
authors.initials: A
authors.lastname: Kakita
authors.forename: H
authors.initials: H
authors.lastname: Mitomi
authors.forename: M
authors.initials: M
authors.lastname: Ohbu
mesh_terms: D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D004947:Esophagus / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009442:Neurilemmoma / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery