title: Mungin, a novel cyclophilin-like antifungal protein from the mung bean.
abstract: A protein designated mungin, isolated from mung bean (Phaseolus mungo) seeds, possessed activity against the fungi Rhizoctonia solani, Coprinus comatus, Mycosphaerella arachidicola, Botrytis cinerea, and Fusarium oxysporum. The 18-kDa protein also possessed a novel N-terminal sequence with similarity to cyclophilins. It exerts an inhibitory action against alpha- and beta-glucosidases suppresses [(3)H]thymidine in corporation by mouse splenocytes.
authors.affiliation: Department of Biochemistry, Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
authors.forename: X Y
authors.initials: XY
authors.lastname: Ye
authors.forename: T B
authors.initials: TB
authors.lastname: Ng
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification*; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification; D007887:Fabaceae / Q000737:chemistry*; D005966:Glucuronidase / Q000037:antagonists & inhibitors; D065089:Glycoside Hydrolase Inhibitors; D051379:Mice; D008969:Molecular Sequence Data; D019696:Peptidylprolyl Isomerase / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal; D017386:Sequence Homology, Amino Acid; D001617:beta-Glucosidase / Q000037:antagonists & inhibitors
chemical_list: D000935:Antifungal Agents; D004791:Enzyme Inhibitors; D065089:Glycoside Hydrolase Inhibitors; D001617:beta-Glucosidase; D005966:Glucuronidase; D019696:Peptidylprolyl Isomerase