Acidic ribosomal proteins and histone H3 from Leishmania present a high rate of divergence.
Another additional peculiarity in Leishmania will be discussed about of the amino acid divergence rate of three structural proteins: acidic ribosomal P1 and P2b proteins, and histone H3 by using multiple sequence alignment and dendrograms. These structural proteins present a high rate of divergence regarding to their homologous protein in Trypanosoma cruzi. At this regard, L. (V.) peruviana P1 and T. cruzi P1 showed 57.4% of divergence rate. Likewise, L. (V.) braziliensis histone H3 and acidic ribosomal P2 protein exhibited 31.8% and 41.7% respectively of rate of divergence in comparison with their homologous in T. cruzi.
Montoya
Y
Y
Instituto Nacional de Salud, Lima, Peru. ymontoya@ins.sld.pe
Padilla
C
C
De Los Santos
M
M
Barreto
T
T
Barker
D
D
Carrillo
C
C
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D006657:Histones / Q000032:analysis*; D007891:Leishmania / Q000737:chemistry* / Q000235:genetics; D010802:Phylogeny; D015800:Protozoan Proteins / Q000032:analysis*; D012269:Ribosomal Proteins / Q000032:analysis*
D000596:Amino Acids; D006657:Histones; D015800:Protozoan Proteins; D012269:Ribosomal Proteins