title: Muscle structure and function in chronic neurological disorders: the potential of exercise to improve activities of daily living.
abstract: Our knowledge of muscle function in chronic neurological disorders, the effects of exercise, and how the effects might translate into improvements in activities of daily living is very limited. By building a bridge between basic muscle physiology and clinical rehabilitation, our knowledge of the pathophysiological mechanisms underlying muscle dysfunction in people with chronic neurological disorders will increase. This will facilitate the design and subsequent evaluation of exercise programs for these people and improve our understanding of the effects of such interventions on performance of activities of daily living.
authors.affiliation: Department of Rehabilitation, Lund University Hospital, Sweden. jan.lexell@skane.se
authors.forename: J
authors.initials: J
authors.lastname: Lexell
mesh_terms: D000203:Activities of Daily Living; D000222:Adaptation, Physiological; D002908:Chronic Disease; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000033:anatomy & histology / Q000503:physiopathology*; D009422:Nervous System Diseases / Q000503:physiopathology / Q000534:rehabilitation; D009468:Neuromuscular Diseases / Q000503:physiopathology* / Q000534:rehabilitation*; D012016:Reference Values