title: Mass spectrometry: a tool for the identification of proteins separated by gels.
abstract: Mass spectrometry (MS) has become the technique of choice to identify proteins. This has been largely accomplished by the combination of high-resolution two-dimensional (2-D) gel separation with robotic sample preparation, automated MS measurement, data analysis, and database query. Developments during the last five years in MS associated with protein gel separation are reviewed.
authors.affiliation: F. Hoffmann-LaRoche Ltd., Pharmaceutical Research, Roche Genetics, Basel, Switzerland. hans-w.lahm@roche.com
authors.forename: H W
authors.initials: HW
authors.lastname: Lahm
authors.forename: H
authors.initials: H
authors.lastname: Langen
mesh_terms: D001331:Automation; D003628:Database Management Systems; D015180:Electrophoresis, Gel, Two-Dimensional; D013058:Mass Spectrometry / Q000379:methods*; D010449:Peptide Mapping; D011506:Proteins / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D011506:Proteins