title: Radical cyclization of beta-aminoacrylates: synthesis of (-)-indolizidine 223AB.
abstract: [reaction: see text] (-)-Indolizidine 223AB was synthesized via radical cyclization of the beta-aminoacrylate derivative of a trans-2,5-disubstituted pyrrolidine. The trans-2,5-disubstituted pyrrolidine substrate was prepared by radical cyclization of a Ses-protected beta-aminoacrylate.
authors.affiliation: School of Chemistry and Molecular Engineering, Seoul National University, Seoul, 151-742, Korea.
authors.forename: E
authors.initials: E
authors.lastname: Lee
authors.forename: E J
authors.initials: EJ
authors.lastname: Jeong
authors.forename: S J
authors.initials: SJ
authors.lastname: Min
authors.forename: S
authors.initials: S
authors.lastname: Hong
authors.forename: J
authors.initials: J
authors.lastname: Lim
authors.forename: S K
authors.initials: SK
authors.lastname: Kim
authors.forename: H J
authors.initials: HJ
authors.lastname: Kim
authors.forename: B G
authors.initials: BG
authors.lastname: Choi
authors.forename: K C
authors.initials: KC
authors.lastname: Koo
mesh_terms: D000818:Animals; D001001:Anura / Q000378:metabolism; D003500:Cyclization; D007202:Indicators and Reagents; D007211:Indoles / Q000138:chemical synthesis*; D007212:Indolizines; D012867:Skin / Q000737:chemistry
chemical_list: D007202:Indicators and Reagents; D007211:Indoles; D007212:Indolizines; C413142:indolizidine 223AB