Estimation of the electric conductivity from scalp measurements: feasibility and application to source localization.
OBJECTIVE
The accuracy of electrical impedance tomography was investigated.


METHODS
The conductivities of the different compartments of the volume conductor were estimated by utilizing the boundary element method. The approach was tested for realistic head models with either 3 or 4 compartments. The impact of a geometrical error in the head model was investigated and the estimated conductivities were assigned to the compartments of the volume conductor used for the source imaging. The localization errors were quantified.


RESULTS
The method used allowed the estimation of the conductivity of the compartments. The poor conductivity of the skull decreased the precision with which the conductivity of deeper structures could be estimated. A geometrical error in the head model was compensated by the estimated conductivities. However, the estimated conductivities did not cancel the geometrical error in the head model as localization errors of the order of 10-20 mm were obtained.


CONCLUSIONS
In principle, the conductivity estimation of the distinct regions in the head is possible. The application of conductivity estimation to increase the accuracy of source localization remains questionable.
van Burik
M J
MJ
Low Temperature Division, Faculty of Applied Physics, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands.
Peters
M J
MJ
D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D003198:Computer Simulation; D006801:Humans; D008959:Models, Neurological; D012535:Scalp / Q000502:physiology*