title: The effectiveness of administering a minimal dose of octreotide long-term prior to surgery for insulinoma: report of a case.
abstract: We report herein the case of an 80-year-old woman with insulinoma who was regarded as an unsuitable candidate for immediate surgery due to her advanced age and obesity, for whom octreotide, a long-acting analogue of somatostatin, was used to improve her hypoglycemia and hyperinsulinemia without hyperalimentation. Administering a minimal dose of octreotide for a long period resulted in the improvement of leg edema, weight control, and cardiopulmonary function, and resection of the pancreatic tumor was safely carried out without any complications.
authors.affiliation: First Department of Surgery, Aichi Medical University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: H
authors.initials: H
authors.lastname: Funahashi
authors.forename: T
authors.initials: T
authors.lastname: Imai
authors.forename: T
authors.initials: T
authors.lastname: Naruse
authors.forename: K
authors.initials: K
authors.lastname: Suzumura
authors.forename: Y
authors.initials: Y
authors.lastname: Oda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006728:Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007340:Insulinoma / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D009765:Obesity / Q000150:complications; D015282:Octreotide / Q000008:administration & dosage / Q000627:therapeutic use*; D010190:Pancreatic Neoplasms / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control; D012307:Risk Factors; D013997:Time Factors
chemical_list: D006728:Hormones; D015282:Octreotide