title: Integration of high resolution EEG and functional magnetic resonance in the study of human movement-related potentials.
abstract: Cortical sources of human movement-related potentials (i.e. unilateral finger extension) were modeled using functional magnetic resonance imaging (fMR) data as a constraint of a linear inverse source estimation from highly sampled (128 channels) EEG data. Remarkably, this estimation was performed within realistic subject's MR-constructed head models by boundary element techniques. An appropriate figure of merit served to set the optimal amount of fMR constraints. With respect to standard linear inverse source estimates, fMR-constrained ones presented increased spatial detail and provided a more reliable timing of activation in bilateral sensorimotor cortical regions of interest.
authors.affiliation: Department of Human Physiology, University of Rome La Sapienza, Rome, Italy [corrected]. babiloni@uniroma1.it
authors.forename: F
authors.initials: F
authors.lastname: Babiloni
authors.forename: F
authors.initials: F
authors.lastname: Carducci
authors.forename: F
authors.initials: F
authors.lastname: Cincotti
authors.forename: C
authors.initials: C
authors.lastname: Del Gratta
authors.forename: G M
authors.initials: GM
authors.lastname: Roberti
authors.forename: G L
authors.initials: GL
authors.lastname: Romani
authors.forename: P M
authors.initials: PM
authors.lastname: Rossini
authors.forename: C
authors.initials: C
authors.lastname: Babiloni
mesh_terms: D000328:Adult; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology*; D003198:Computer Simulation; D004569:Electroencephalography; D019054:Evoked Potentials, Motor / Q000502:physiology; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007537:Isometric Contraction / Q000502:physiology; D016014:Linear Models; D008279:Magnetic Resonance Imaging; D009043:Motor Activity / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted