title: Sonography of extraaxial fluid in neurologically normal infants with head circumference greater than or equal to the 95th percentile for age.
abstract: The goal of this study was to examine sonographically the extraaxial space in neurologically normal infants with occipital frontal circumference greater than or equal to the 95th percentile for age and correlate these dimensions with neurologic follow-up findings to determine a range of normal values. We thus hope to obviate unnecessary workup of these patients, including additional imaging or intervention. Our results demonstrate that for infants with a craniocortical width or sinocortical width less than 10 mm, the negative predictive value and specificity for developing a neurologic abnormality during the 55 week follow-up period were 94 to 100%. Thus, for neurologically normal infants with occipital frontal circumference greater than or equal to the 95th percentile for age and a head ultrasonogram that is otherwise normal, a craniocortical or sinocortical width of up to 10 mm can be considered within normal limits. Clinical follow-up evaluation is prudent, but additional imaging of these infants is not required.
authors.affiliation: Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109-0326, USA.
authors.forename: D P
authors.initials: DP
authors.lastname: Fessell
authors.forename: D A
authors.initials: DA
authors.lastname: Frankel
authors.forename: W P
authors.initials: WP
authors.lastname: Wolfson
mesh_terms: D002508:Cephalometry; D002555:Cerebrospinal Fluid / Q000000981:diagnostic imaging*; D005500:Follow-Up Studies; D006257:Head / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D009422:Nervous System Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging; D011237:Predictive Value of Tests; D012016:Reference Values; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014463:Ultrasonography