title: [An assessment of the efficacy of stress-protector pharmacological preparations and hyperbaric oxygenation in patients in the perioperative period].
abstract: Modulating effects of some drugs and HBO on adaptation reaction have been studied in 74 surgical patients. Investigation methods included cardiac rhythm record (statistical analysis with histogram plotting--sympathetic activity index), tcpO2, tcpCO2, SaO2, finger pulse amplitude (vasomotor tone evaluation), and evaluation of changes in arterial pressure and heart rate. The treatment included intravenous propranolol (0.92-1.38 micrograms/kg/min) or cordanum (1.85-2.7 micrograms/kg/min) or clonidine (0.018-0.037 microgram/kg/min) or dalargin (0.55-0.83 microgram/kg/min) HBO-100% O2 for 1 h at 1.5 ATA during increase of sympathetic activity. The results indicate that all drugs and HBO modulate the adaptation response of the organism and improve the outcomes of surgery.
authors.forename: Iu Iu
authors.initials: IuIu
authors.lastname: Kiriachkov
authors.forename: Ia M
authors.initials: IaM
authors.lastname: Khmelevskiĭ
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Sloventantor
authors.forename: E V
authors.initials: EV
authors.lastname: Vorontsova
mesh_terms: D000222:Adaptation, Physiological / Q000187:drug effects; D000465:Algorithms; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009420:Nervous System / Q000187:drug effects*; D019990:Perioperative Care / Q000379:methods* / Q000706:statistics & numerical data; D013312:Stress, Physiological / Q000517:prevention & control*; D013997:Time Factors