title: [Cognitive dysfunction in schizophrenia--analysis using exploratory eye movements].
abstract: Studies of exploratory eye movements on patients with schizophrenia were reviewed. Cognitive dysfunction in schizophrenia was examined from two aspects: the schema by Neisser, and the reaction to an object or a stimulus using exploratory eye movements. The schema by which subjects view an object with a spacial spread and with a sequence of time was disturbed in schizophrenia patients, and this schema was not changeable in the response to various conditions in these patients compared with non-schizophrenic individuals. The responsive search score (RSS) in schizophrenia was extracted as the disturbance of schema in the interpersonal setting. The lowering of RSS was a common feature in many patients with schizophrenia and remarkably reflects a trait of schizophrenia. We discussed a relationship between the RSS and other trait markers in schizophrenia, and it was suggested that the concept of "Disturbance of Schema" can explain abnormal results of other indicators and can lead us to understand several theories of cognitive dysfunction in schizophrenia.
authors.affiliation: Department of Neuropsychiatry, Nihon University School of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Kojima
authors.forename: E
authors.initials: E
authors.lastname: Matsushima
mesh_terms: D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology; D005133:Eye Movements; D020022:Genetic Predisposition to Disease; D006801:Humans; D011930:Reaction Time; D012559:Schizophrenia / Q000235:genetics / Q000503:physiopathology*; D012565:Schizophrenic Psychology