[Use of S100b protein for optimization of cornea regeneration after surgery].
The results presented suggest a modulating effect of protein S100b on the course of inflammation in the cornea. In the presence of this protein, secretion of proteoglycans and collagen increases, their interrelationship is restored and tissue specificity of extracellular matrix is ensured, which allows preservation of the cornea transparency. Protein S100b appears to be a promising drug for ophthalmology, especially after refractional surgery on the cornea.
Ziangarova
G G
GG
Research Institute of Eye Diseases, Russian Academy of Medical Sciences, Moscow, Russia.
Olinevich
V B
VB
D000818:Animals; D002135:Calcium-Binding Proteins / Q000494:pharmacology*; D002455:Cell Division; D002465:Cell Movement; D003315:Cornea / Q000187:drug effects* / Q000294:innervation / Q000378:metabolism / Q000473:pathology; D005347:Fibroblasts / Q000473:pathology; D054018:Lasers, Excimer; D009414:Nerve Growth Factors / Q000494:pharmacology*; D009504:Neutrophils / Q000473:pathology; D018903:Photorefractive Keratectomy; D011509:Proteoglycans / Q000378:metabolism; D011817:Rabbits; D012038:Regeneration; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins; D014945:Wound Healing / Q000187:drug effects*
D002135:Calcium-Binding Proteins; D009414:Nerve Growth Factors; D011509:Proteoglycans; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins