Malignant mesothelioma with CD30-positivity. A case report and review of the literature.
The activation marker CD3O is useful in the diagnosis of Hodgkin and non-Hodgkin lymphomas. It has also been described in nonhematopoietic tumors, including pancreatic carcinomas, salivary gland tumors, and embryonal carcinomas. We report a case of malignant mesothelioma with intense CD30 positivity. This finding has not previously been described and is important in broadening the differential diagnosis of a CD30(+) cohesive large cell malignancy.
Dunphy
C H
CH
Division of Hematopathology, Department of Pathology, Saint Louis University Health Sciences Center St Louis, MO, USA.
Gardner
L J
LJ
Bee
C S
CS
D000368:Aged; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D017730:Ki-1 Antigen / Q000378:metabolism*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008654:Mesothelioma / Q000000981:diagnostic imaging / Q000276:immunology* / Q000473:pathology*; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging / Q000276:immunology* / Q000473:pathology*; D014057:Tomography, X-Ray Computed
D017730:Ki-1 Antigen