The controlled chaos of shifty pathogens.
Bacterial pathogens use novel mechanisms to vary their surface structures. Three new genome sequences provide a perspective on these mechanisms in Borrelia burgdorferi, Neisseria meningitidis, and Campylobacter jejuni, which cause lyme disease, meningitis and gastroenteritis, respectively.
Faguy
D M
DM
Department of Biology, University of New Mexico, Albuquerque, USA. dfaguy@unm.edu
D000595:Amino Acid Sequence; D000940:Antigenic Variation; D001483:Base Sequence; D015748:Borrelia burgdorferi Group / Q000235:genetics; D016123:Campylobacter jejuni / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics*; D014644:Genetic Variation; D016680:Genome, Bacterial; D006801:Humans; D008969:Molecular Sequence Data; D009345:Neisseria meningitidis / Q000235:genetics; D017386:Sequence Homology, Amino Acid
D004269:DNA, Bacterial