[The spectrum of cytotoxic lymphomas of the skin].
Cytotoxic lymphomas are peripheral T- and natural killer-cell lymphomas with primary or secondary skin manifestations. They constitute a heterogeneous group of lymphoproliferative disease. They are characterized by expression of cytotoxic proteins and are frequently associated with an aggressive clinical course. A brief introduction to cytotoxic lymphocytes and proteins is followed by a detailed description of clinical, histological, immunohistochemical and genetic characteristics of cutaneous cytotoxic lymphomas.
el Shabrawi-Caelen
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L
Universitätsklinik für Dermatologie und Venerologie Graz.
Cerroni
L
L
Sterry
W
W
Audring
H
H
Kerl
H
H
D006801:Humans; D016130:Immunophenotyping; D007694:Killer Cells, Natural / Q000276:immunology*; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis* / Q000276:immunology; D016411:Lymphoma, T-Cell, Peripheral / Q000175:diagnosis* / Q000276:immunology; D012878:Skin Neoplasms / Q000175:diagnosis / Q000276:immunology*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*