Endoscopic injection sclerotherapy control of intractable hematuria following radiation-induced hemorrhagic cystitis. A novel approach.
OBJECTIVE
To establish the utility of endoscopic sclerotherapy using 1% ethoxysclerol for the control of intractable hematuria following post-irradiation telangiectatic cystitis (PTC).


METHODS
Our experience of treating 4 patients (one female and three male) with massive exsanguinating hematuria resulting from PTC, using a combined intralesional and perilesional injection of 1% ethoxysclerol, is presented. Observation on the distribution, grading of telangiectasis and pattern of bleeding are made.


RESULTS
A dramatic and lasting cessation of the hematuria in all the 4 patients was achieved during the follow-up period varying from 1 month to 4 years.


CONCLUSIONS
Endoscopic injection sclerotherapy is a simple, highly effective, less invasive new technique in the management of massive and intractable hematuria due to radiation-induced telangiectasia of the urinary bladder.
Tunuguntla
H S
HS
Department of Urology and Renal Transplantation, Sanjay Ghandi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India. siva@sgpgi.ac.in
Bhandari
M
M
Srivastava
A
A
Kapoor
R
R
Saha
T K
TK
D000328:Adult; D003556:Cystitis / Q000209:etiology*; D005260:Female; D006417:Hematuria / Q000188:drug therapy* / Q000209:etiology*; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D000077423:Polidocanol; D011092:Polyethylene Glycols / Q000008:administration & dosage*; D011878:Radiotherapy / Q000009:adverse effects*; D012597:Sclerosing Solutions / Q000008:administration & dosage*; D015911:Sclerotherapy
D012597:Sclerosing Solutions; D000077423:Polidocanol; D011092:Polyethylene Glycols