title: Talc granulomatosis. A differential diagnosis of interstitial lung disease in HIV patients.
abstract: Consumers of adulterated drugs may present with talc-induced interstitial lung disease. A transbronchial biopsy specimen showing granulomas with intracellular talc crystals is necessary to confirm this diagnosis. In patients infected with HIV, such a condition can be indistinguishable at first glance from opportunistic infections or other pulmonary diseases. A case is presented of a seropositive patient whose chest radiographs showed a diffuse interstitial pattern.
authors.affiliation: Infectious Diseases Unit, Department of Internal Medicine, Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, Spain.
authors.forename: D N
authors.initials: DN
authors.lastname: Nan
authors.forename: M
authors.initials: M
authors.lastname: Fernández-Ayala
authors.forename: L
authors.initials: L
authors.lastname: Iglesias
authors.forename: D
authors.initials: D
authors.lastname: García-Palomo
authors.forename: J A
authors.initials: JA
authors.lastname: Parra
authors.forename: M C
authors.initials: MC
authors.lastname: Fariñas
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D015745:Granuloma, Foreign-Body / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D015769:Granuloma, Respiratory Tract / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008297:Male; D011859:Radiography; D013627:Talc / Q000009:adverse effects*
chemical_list: D013627:Talc