[Prophylactic effect of antioxidant Aekol on behavioral (psychoemotional) disturbances caused by chronic stress in rats].
Antioxidant preparation "Aekol" containing vitamins A, E, and K3, was shown to possess antidepressant properties and to exert a prophylactic effect on behavioural (psychoemotional) disturbances induced by a chronic stress in rats: a depressive condition associated with an enhanced anxiety, elimination of individual differences in behaviour, weakening of the relationships among behavioural parameters recorded in the same animal in three different tests.
Sarkisova
K Iu
KIu
Institute of Higher Nervous Activity and Neurophysiology, Russian Acad. Sci., Moscow, Russia.
Kulikov
M A
MA
D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D001007:Anxiety / Q000209:etiology / Q000517:prevention & control / Q000523:psychology; D001522:Behavior, Animal / Q000187:drug effects*; D003863:Depression / Q000209:etiology / Q000517:prevention & control / Q000523:psychology; D004338:Drug Combinations; D008297:Male; D009497:Neurotic Disorders / Q000209:etiology / Q000517:prevention & control* / Q000523:psychology; D051381:Rats; D017208:Rats, Wistar; D013312:Stress, Physiological / Q000150:complications / Q000523:psychology*; D014801:Vitamin A / Q000494:pharmacology*; D014810:Vitamin E / Q000494:pharmacology*; D014812:Vitamin K / Q000494:pharmacology*
D000928:Antidepressive Agents; D000975:Antioxidants; D004338:Drug Combinations; D014801:Vitamin A; D014812:Vitamin K; C059630:vitamin A, vitamin E, vitamin K3 drug combination; D014810:Vitamin E