title: Antimicrobial resistance in European isolates of Pseudomonas aeruginosa. European SENTRY Participants.
abstract: Pseudomonas aeruginosa is responsible for a substantial fraction of hospital infections. Twenty-five European university hospitals submitted a total of 1411 Pseudomonas aeruginosa isolates for susceptibility testing during 1997 and 1998. The isolates showed highest susceptibility to amikacin (87.5%), meropenem (87.3%) and piperacillin/tazobactam (86.8%). Susceptibility to ciprofloxacin was 73.2%. There was no clear geographical distribution of resistance, although isolates from northwestern Europe tended to be more susceptible than those from southeastern Europe. Isolates that were resistant to one class of antibiotics were also often resistant to at least one other class of antibiotics. Imipenem-resistant isolates were generally not clonally related.
authors.affiliation: Eijkman-Winkler Institute, University Medical Center Utrecht, The Netherlands. A.C.Fluit@lab.azu.nl
authors.forename: A C
authors.initials: AC
authors.lastname: Fluit
authors.forename: J
authors.initials: J
authors.lastname: Verhoef
authors.forename: F J
authors.initials: FJ
authors.lastname: Schmitz
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D005060:Europe; D006785:Hospitals, University; D006801:Humans; D008826:Microbial Sensitivity Tests; D011552:Pseudomonas Infections / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents