Genetic studies of substance abuse.
Genetic studies of substance abuse indicate that variation in the risk for the disorder in the population is contributed by differences in both individual genotypes and environment. Recent developments in genetics raise the possibility of disentangling the complex system of genotype-environment interaction that determines the development of the individual behavioral phenotype. This paper reviews the concepts, methods and results pertaining to genetic investigation of substance abuse.
Vanyukov
M M
MM
Center for Education and Drug Abuse Research, University of Pittsburgh, 3811 O'Hara Street, PA 15213, USA. mmv@vms.cis.pitt.edu
Tarter
R E
RE
D000437:Alcoholism / Q000235:genetics* / Q000523:psychology; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005838:Genotype; D006801:Humans; D010641:Phenotype; D012307:Risk Factors; D012931:Social Environment; D019966:Substance-Related Disorders / Q000235:genetics* / Q000523:psychology