A Concise Route to (+)-Estrone.
A concise route to the Torgov diene, the key intermediate of estrone, has been devised using a chiral dioxycyclopentenone as the starting material by employing a sequence of five steps of reactions involving a Lewis acid-mediated Diels-Alder reaction with Dane's diene.
Tanaka
K
Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-8578, Japan.
Nakashima
H
Taniguchi
T
Ogasawara
K