Opposing effects of IL-1 alpha and IL-1 beta on malignancy patterns. Tumor cell-associated IL-1 alpha potentiates anti-tumor immune responses and tumor regression, whereas IL-1 beta potentiates invasiveness.
Apte
R N
RN
Department of Microbiology and Immunology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel.
Dvorkin
T
T
Song
X
X
Fima
E
E
Krelin
Y
Y
Yulevitch
A
A
Gurfinkel
R
R
Werman
A
A
White
R M
RM
Argov
S
S
Shendler
Y
Y
Bjorkdahl
O
O
Dohlsten
M
M
Zoller
M
M
Segal
S
S
Voronov
E
E
D000818:Animals; D016588:Anticarcinogenic Agents / Q000276:immunology; D002470:Cell Survival / Q000187:drug effects; D018014:Gene Transfer Techniques; D015316:Genetic Therapy; D006801:Humans; D007375:Interleukin-1 / Q000235:genetics / Q000276:immunology* / Q000627:therapeutic use; D009369:Neoplasms / Q000276:immunology* / Q000628:therapy; D020033:Protein Isoforms / Q000235:genetics / Q000276:immunology / Q000627:therapeutic use
D016588:Anticarcinogenic Agents; D007375:Interleukin-1; D020033:Protein Isoforms