Beneficial effect of fluoxetine in a case of sporadic hyperekplexia.
We studied a 67-year-old woman with a sporadic form of hyperekplexia, who experienced 8-10 excessive startle responses to unexpected stimuli per month. Therapy with fluoxetine had a definite beneficial effect. This finding supports the hypothesis that serotonergic mechanisms play a role in this disorder.
Sechi
G
G
Department of Neurology, University of Sassari, Italy.
Sotgiu
S
S
Valenti
M P
MP
Pitzolu
M G
MG
Peterlongo
P
P
Larizza
L
L
Rosati
G
G
D000368:Aged; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use*; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy* / Q000378:metabolism / Q000523:psychology; D013216:Reflex, Startle / Q000187:drug effects*; D012701:Serotonin / Q000502:physiology
D018687:Antidepressive Agents, Second-Generation; D005473:Fluoxetine; D012701:Serotonin