title: UV-A and PUV-A action on Sendai virus HN glycoprotein.
abstract: The UV-A and PUV-A treatments were applied on the Sendai virus and the changes of the biological properties of HN surface glycoprotein were monitorized. Under the UV-A action the HA and NA activities are inhibited in a dose-correlated way. When the irradiation was done in the presence of a photoreagent (8-MOP) the HA activity remained unchanged, but the enzymic activity was affected. The possible mechanisms of these inhibition processes are discussed.
authors.affiliation: Stefan S. Nicolau Institute of Virology, Bucharest.
authors.forename: L
authors.initials: L
authors.lastname: Obeadă
authors.forename: A
authors.initials: A
authors.lastname: Pleşa
authors.forename: R
authors.initials: R
authors.lastname: Repanovici
mesh_terms: D004307:Dose-Response Relationship, Radiation; D015707:HN Protein / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D006386:Hemagglutination Tests; D008730:Methoxsalen / Q000494:pharmacology; D009439:Neuraminidase / Q000378:metabolism; D011701:PUVA Therapy; D018108:Respirovirus / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D014466:Ultraviolet Rays
chemical_list: D015707:HN Protein; D009439:Neuraminidase; D008730:Methoxsalen