[External progressive ophthalmoplegia secondary to mitochondrial myopathy. Report of a case and review of the literature].
Progressive limitation of occular motility, accompanied by ptosis but usually without diplopia, occurs in many pathologic states, including mitochondrial diseases. A case with chronic progressive external ophthalmoplegia with onset during childhood, associated with proximal myopathy and dysphasia is presented. The muscle biopsy showed a myopathic pattern and abnormal subsarcolemmal mitochondrial deposits. Muscle biopsy for important in the correct diagnosis of this entity.
Calderón-Garcidueñas
A L
AL
Servicio de Anatomía Patológica y Neurología, Hospital de Especialidades, Centro Médico del Noreste, IMSS, Monterrey, N.L. acalder@mail.giga.com
Pérez-Loria
O
O
Alberto-Sagástegui
J
J
Farías-García
R
R
D000328:Adult; D018450:Disease Progression; D005260:Female; D006801:Humans; D017240:Mitochondrial Myopathies / Q000150:complications* / Q000473:pathology; D009886:Ophthalmoplegia / Q000209:etiology*