title: The Erve virus: possible mode of transmission and reservoir.
abstract: The Erve virus is suspected to cause severe headache in humans, lasting several days (thunderclap headache). Mice are characterized as a probable reservoir for the Erve virus. We tested 396 wild mice for Erve virus using an immunofluorescence test and found Erve virus antibodies in five cases, showing that small mammals form a reservoir for Erve virus. If ticks are the vector for the virus, a coincidence with borreliosis should exist. We were unable to confirm this in a homogeneous cohort of 955 young men, 62 of whom tested positive for borreliosis. This group did not test positive significantly more often in the immunofluorescence test than a gender- and age-matched control group.
authors.affiliation: Dept of Neurology, Westpfalz Clinic, Kaiserslautern, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Woessner
authors.forename: M T
authors.initials: MT
authors.lastname: Grauer
authors.forename: J
authors.initials: J
authors.lastname: Langenbach
authors.forename: G
authors.initials: G
authors.lastname: Dobler
authors.forename: J
authors.initials: J
authors.lastname: Kroeger
authors.forename: H G
authors.initials: HG
authors.lastname: Mielke
authors.forename: P
authors.initials: P
authors.lastname: Mueller
authors.forename: A
authors.initials: A
authors.lastname: Haass
authors.forename: J
authors.initials: J
authors.lastname: Treib
mesh_terms: D000328:Adult; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood*; D015748:Borrelia burgdorferi Group / Q000276:immunology; D002043:Bunyaviridae / Q000276:immunology*; D002044:Bunyaviridae Infections / Q000453:epidemiology / Q000635:transmission* / Q000821:virology; D015897:Comorbidity; D004197:Disease Reservoirs / Q000662:veterinary*; D018562:Disease Transmission, Infectious; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008193:Lyme Disease / Q000453:epidemiology / Q000382:microbiology; D008297:Male; D051379:Mice; D009115:Muridae / Q000821:virology*; D016036:Seroepidemiologic Studies
chemical_list: D000907:Antibodies, Bacterial; D000914:Antibodies, Viral