Cutaneous mastocytomas in Djungarian hamsters.
Spontaneous cutaneous mastocytomas in Djungarian hamsters (D-hamster) were pathologically studied and compared with those in canine and feline cases. Eight (9.3%) of 86 cutaneous biopsy cases in D-hamsters were diagnosed as mastocytomas, being slightly higher in incidence than in canine and feline species. In 4 of 8 D-hamster cases, the tumor lesions were in the head and neck in contrast to most canine lesions in the extremities. The histopathology of the D-hamster mastocytoma was characterized by diffuse or massive proliferation of well-differentiated tumor cells with severe degeneration of collagen fibers and slight eosinophil infiltration in most cases.
Nishizumi
K
K
Laboratory of Veterinary Pathobiology, Nihon University School of Veterinary Medicine, Fujisawa, Japan.
Fujiwara
K
K
Hasegawa
A
A
D000818:Animals; D002415:Cats; D053818:Chymases; D006224:Cricetinae; D004285:Dogs; D005260:Female; D007124:Immunoenzyme Techniques; D008297:Male; D008407:Mast Cells / Q000648:ultrastructure; D012515:Mast-Cell Sarcoma / Q000737:chemistry / Q000473:pathology / Q000662:veterinary*; D017111:Phodopus; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis; D012697:Serine Endopeptidases / Q000032:analysis; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology / Q000662:veterinary*; D013045:Species Specificity; D053802:Tryptases
D018809:Proliferating Cell Nuclear Antigen; D012697:Serine Endopeptidases; C083294:chymase 2; D053818:Chymases; D053802:Tryptases