Prognosis related to staging systems for chronic lymphocytic leukemia.
BACKGROUND
Chronic lymphocytic leukemia (CLL) is a clonal lymphoproliferative disorder, characterized by B lymphocytic proliferation. CLL is the most frequent adult leukemia in Western countries, accounting for 25 to 30% of all white leukemic patients.


OBJECTIVE
To evaluate clinical and staging characteristics in prognosis of chronic lymphocytic leukemia.


METHODS
Evaluation of clinical-staging data.


METHODS
Universidade Federal de São Paulo - Escola Paulista de Medicina / Universidade de Alfenas.


METHODS
73 patients diagnosed from 1977 to 1994.


METHODS
Sex, ethnic origin, age, lymphadenopathy, splenomegaly, hepatomegaly, three or more areas of lymphoid enlargement, hemoglobin (g/dl), lymphocytes/mm3, Platelets/mm3


RESULTS
Mean survival of patients was 76 months, median age was 65 years, ranging from 33 to 87. Forty-four patients (60.3%) were male and 29 (39.7%) female.


CONCLUSIONS
The Binet system determined a better prognosis than Rai.
de Faria
J R
JR
Division of Hematology, Universidade de Alfenas, Minas Gerais, Brazil.
de Oliveira
J S
JS
Delbone de Faria
R M
RM
Silva
M R
MR
Goihman
S
S
Yamamoto
M
M
Kerbauy
J
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000401:mortality / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D017741:Survivors