A comparison of alternative assessments of depressive symptom severity: a pilot study.
This study compared the performance of an itemized symptom self-report (Inventory of Depressive Symptomatology - Self-Report; IDS-SR), patient global ratings, and clinician global ratings with an itemized clinician-rated symptom severity measure (Inventory of Depressive Symptomatology - Clinician-Rated; IDS-C) in detecting treatment effects in patients with major depressive disorder (MDD). A total of 28 inpatients (30.8% psychotic) and 34 outpatients (17.9% psychotic) with MDD began treatment that followed the Texas medication algorithm. The clinicians completed the IDS-C and a Physician Global Rating Scale (PhGRS) at each assessment visit, while the patients completed the IDS-SR and a Patient Global Rating Scale (PtGRS). Change scores from the baseline to subsequent weeks were computed for all subjects, utilizing all four measures. The IDS-SR was a significant independent predictor of the response to treatment as compared to the two global ratings. The IDS-SR was as sensitive to change as the IDS-C. While the clinician-rated itemized symptom severity rating scale remains the standard to assess the symptomatic outcome of the treatment of MDD, a self-report of identical symptomatology may be a reasonable alternative for many patients.
Biggs
M M
MM
Department of Psychiatry, University of Texas, Southwestern Medical Center, Dallas, TX 75390-9086, USA. mbiggs@mednet.swmed.edu
Shores-Wilson
K
K
Rush
A J
AJ
Carmody
T J
TJ
Trivedi
M H
MH
Crismon
M L
ML
Toprac
M G
MG
Mason
M
M
Biggs
M M
MM
D000328:Adult; D000465:Algorithms; D000928:Antidepressive Agents / Q000627:therapeutic use; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010552:Personality Assessment / Q000706:statistics & numerical data*; D010555:Personality Inventory / Q000706:statistics & numerical data*; D010865:Pilot Projects; D011594:Psychometrics; D015203:Reproducibility of Results; D016896:Treatment Outcome
D000928:Antidepressive Agents