title: [Sepsis on the threshold of the 21st century: the basic results. New problems and the immediate tasks].
abstract: The authors validate their positions in terminology of sepsis and evaluation of its severity, based on analysis of this problem evolution during the century, review of the most significant publications, and their own findings. Problems of intensive care are discussed. The authors claim that intensive care methods should be determined by the phase of the systemic inflammatory response syndrome (SIRS). One of the nearest goals for scientists and public health managers is an interdisciplinary consensus on terminology of sepsis and diagnostic criteria, creation of a standard protocol of laboratory studies and treatment, search for available markers of SIRS of infectious origin, regulation of cytokine response, creation of local data bases reflecting the etiological structure of the agents and their antibiotic resistance.
authors.forename: V A
authors.initials: VA
authors.lastname: Rudnov
authors.forename: D A
authors.initials: DA
authors.lastname: Vishnitskiĭ
mesh_terms: D003422:Critical Care / Q000379:methods; D006801:Humans; D018805:Sepsis / Q000175:diagnosis* / Q000628:therapy; D012720:Severity of Illness Index; D009626:Terminology as Topic