Mitochondrial DNA variants in schizophrenia: association studies.
The frequency of three selected mitochondrial DNA variations was compared between cases with schizophrenia and two groups of unrelated controls: screened adults and neonates. The comparisons were conducted separately among Caucasians and African-Americans. No significant differences were detected, suggesting that the variants may not be associated with schizophrenia. Limitations of the study are discussed.
Gentry
K M
KM
Department of Psychiatry, University of Pittsburgh, PA 15213, USA.
Nimgaonkar
V L
VL
D000328:Adult; D044383:Black People / Q000235:genetics; D003573:Cytochrome b Group / Q000235:genetics; D004252:DNA Mutational Analysis; D004272:DNA, Mitochondrial / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D007231:Infant, Newborn; D010414:Pennsylvania / Q000453:epidemiology; D012335:RNA, Ribosomal / Q000235:genetics; D012559:Schizophrenia / Q000453:epidemiology / Q000235:genetics*; D044465:White People / Q000235:genetics; D001741:Black or African American
D003573:Cytochrome b Group; D004272:DNA, Mitochondrial; D012335:RNA, Ribosomal; C075526:RNA, ribosomal, 12S