title: Effects of short-term exposure to condensed tannins on adult Trichostrongylus colubriformis.
abstract: Twelve parasite-naive sheep were used to study the possible direct anthelmintic effect of a condensed tannin extract (quebracho) on the population and fecundity of the intestinal nematode Trichostrongylus colubriformis. The sheep were infected with a single dose of 20,000 L3 of T colubriformis. Twenty-eight days later, six of them were drenched daily for a week with quebracho extract at 8 per cent by weight of their food intake. All lambs were then slaughtered, and their small intestines removed to estimate the worm burdens and the numbers of eggs in utero. Two days after the first drench with tannin extract the faecal egg counts of the treated sheep were approximately 50 per cent of those of the control sheep (P<0.01), but there was no further reduction with continued drenching. In the treated sheep the worm burdens and number of eggs per gram faeces per worm were reduced by 30 per cent compared with the controls (P<0.05), but the sex ratios, the number of eggs in utero and length of the worms were not affected by drenching with tannin.
authors.affiliation: Animal Biology Division, Scottish Agricultural College, Edinburgh.
authors.forename: S
authors.initials: S
authors.lastname: Athanasiadou
authors.forename: I
authors.initials: I
authors.lastname: Kyriazakis
authors.forename: F
authors.initials: F
authors.lastname: Jackson
authors.forename: R L
authors.initials: RL
authors.lastname: Coop
mesh_terms: D000287:Administration, Topical; D000818:Animals; D007421:Intestine, Small / Q000469:parasitology; D010270:Parasite Egg Count; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy / Q000469:parasitology*; D013634:Tannins / Q000494:pharmacology*; D014253:Trichostrongylosis / Q000662:veterinary*; D014254:Trichostrongylus / Q000187:drug effects* / Q000469:parasitology
chemical_list: D013634:Tannins