title: [POEMS syndrome--a case report].
abstract: One rare case of POEMS syndrome is presented. In a 39-year-old male patient a progressive numbness in hands and feet developed within 5 years. Admission with increasing dyspnoea and lower leg edema. In swollen inguinal lymph nodes a lymphadenopathy with angiofollicular hyperplasia and vascular-plasmacellular proliferation was diagnosed and classified as Castleman-like histologic features. In os ilium an osteosclerotic plasmocytoma with restriction of kappa light chains was found. Potential pathomechanism of POEMS syndrome are discussed.
authors.affiliation: Institut für Pathologie, Friedrich-Schiller-Universität Jena.
authors.forename: H
authors.initials: H
authors.lastname: Ebhardt
authors.forename: T
authors.initials: T
authors.lastname: Eidner
authors.forename: A
authors.initials: A
authors.lastname: Berndt
authors.forename: D
authors.initials: D
authors.lastname: Katenkamp
authors.forename: H
authors.initials: H
authors.lastname: Kosmehl
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000276:immunology / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D008206:Lymphatic Diseases; D008297:Male; D016878:POEMS Syndrome / Q000145:classification / Q000473:pathology*; D010954:Plasmacytoma / Q000276:immunology / Q000473:pathology
chemical_list: D007145:Immunoglobulin kappa-Chains