title: RhoB is expressed in migrating neural crest and endocardial cushions of the developing mouse embryo.
abstract: RhoB mRNA expression was examined in the developing mouse embryo between E8.5 and E11.5. Specific expression was found in migrating neural crest (NC) cells, from the first stages of their migration at E9.5, throughout the migration period. Expression is maintained in NC derivatives for at least one embryonic day after they reach their final destinations, but is then down-regulated. RhoB is also expressed in non NC-derived neural tissues, including motor neurones and the floor plate of the neural tube. RhoB mRNA expression is also found in the developing endocardial cushions of the atrioventricular and outflow regions of the developing heart.
authors.affiliation: Neural Development Unit, Institute of Child Health, University College London, 30 Guilford Street, WC1N 1EH, London, UK. dhender@ich.ucl.ac.uk
authors.forename: D J
authors.initials: DJ
authors.lastname: Henderson
authors.forename: P
authors.initials: P
authors.lastname: Ybot-Gonzalez
authors.forename: A J
authors.initials: AJ
authors.lastname: Copp
mesh_terms: D000818:Animals; D002465:Cell Movement / Q000502:physiology*; D005314:Embryonic and Fetal Development; D004699:Endocardium / Q000196:embryology* / Q000502:physiology*; D051379:Mice; D009432:Neural Crest / Q000196:embryology* / Q000502:physiology*; D020743:rhoB GTP-Binding Protein / Q000502:physiology*
chemical_list: D020743:rhoB GTP-Binding Protein