title: Ribosomal protein S6 cDNA from two Aedes mosquitoes encodes a carboxyl-terminal extension that resembles histone H1 proteins.
abstract: Ribosomal protein S6 (rpS6) is the major phosphorylated protein on the eukaryotic ribosome. Because electrophoretic evidence suggested that the homolog of rpS6 from the mosquitoes Aedes albopictus and Aedes aegypti was measurably larger than Drosophila rpS6, we have now isolated full-length cDNAs encoding Aedes albopictus and Aedes aegypti rpS6. The mosquito rpS6 cDNAs encoded a 100 amino acid extension at the carboxyl-terminus, relative to rpS6 from humans and Drosophila. This region had homology to cDNAs encoding histone H1 from various species and accounted for the larger size of the mosquito protein on polyacrylamide gels. On Northern blots, the mosquito cDNA hybridized to a single band measuring approximately 1.2 kb.
authors.affiliation: Department of Entomology, University of Minnesota, St. Paul 55108, USA.
authors.forename: V P
authors.initials: VP
authors.lastname: Hernandez
authors.forename: A M
authors.initials: AM
authors.lastname: Fallon
mesh_terms: D000330:Aedes / Q000737:chemistry / Q000235:genetics*; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004330:Drosophila / Q000235:genetics; D006657:Histones / Q000737:chemistry*; D019476:Insect Proteins / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D014176:Protein Biosynthesis; D038601:Ribosomal Protein S6; D012269:Ribosomal Proteins / Q000737:chemistry / Q000235:genetics*; D017386:Sequence Homology, Amino Acid
chemical_list: D006657:Histones; D019476:Insect Proteins; D038601:Ribosomal Protein S6; D012269:Ribosomal Proteins