title: [Intravenous lignocaine for chronic pain: an 18-month experience].
abstract: Intravenous injection of lignocaine relieves pain in animals with experimentally induced pain, and in man, mainly those with neuropathic pain. 106 patients were treated with intravenous lignocaine during a period of 18 months (212 treatment sessions). Blood pressure, heart rate and pain scores were continuously monitored after an intravenous bolus of lignocaine, 1 mg/kg, followed by continuous infusion of lignocaine, 5 mg/kg during 1 hour. There was significant pain relief after each session in most patients, lasting from a few hours to 4 weeks. There were no significant side effects. We present 2 of our patients. Due to its simplicity, efficacy and safety, intravenous lignocaine injection is recommended for those with neuropathic pain unrelieved by other therapeutic modalities.
authors.affiliation: Pain Treatment Services, Dept. of Anesthesiology of Sheba Medical Center, University Hospital, Jerusalem.
authors.forename: A
authors.initials: A
authors.lastname: Cahana
authors.forename: V
authors.initials: V
authors.lastname: Shvelzon
authors.forename: O
authors.initials: O
authors.lastname: Dolberg
authors.forename: F
authors.initials: F
authors.lastname: Magora
authors.forename: Y
authors.initials: Y
authors.lastname: Shir
mesh_terms: D000328:Adult; D000368:Aged; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000627:therapeutic use*; D001794:Blood Pressure; D002908:Chronic Disease; D005260:Female; D006339:Heart Rate; D006801:Humans; D007262:Infusions, Intravenous; D007275:Injections, Intravenous; D008012:Lidocaine / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*; D010147:Pain Measurement
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine