title: The use of growth factors in cartilage repair.
abstract: Articular cartilage, which enables smooth gliding of joints during skeletal motion, is vulnerable to injuries and degenerative diseases over time. Bone growth factors have a role in the preservation of the cartilage matrix. This article reviews the potential to treat cartilage damage for bone morphogenetic proteins, insulin-like growth factors, hepatocyte growth factor, basic fibroblast growth factor, and transforming growth factor beta.
authors.affiliation: Department of Orthopedic Surgery, Hospital for Special Surgery, New York, New York 10021, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: O'Connor
authors.forename: T
authors.initials: T
authors.lastname: Botti
authors.forename: S N
authors.initials: SN
authors.lastname: Khan
authors.forename: J M
authors.initials: JM
authors.lastname: Lane
mesh_terms: D000818:Animals; D002358:Cartilage, Articular / Q000293:injuries* / Q000503:physiopathology; D006133:Growth Substances / Q000008:administration & dosage* / Q000502:physiology; D006801:Humans; D010003:Osteoarthritis / Q000503:physiopathology / Q000628:therapy*; D011379:Prognosis
chemical_list: D006133:Growth Substances