[Genetic prediction in medicine].
Presymptomatic or predictive genetic testing concerns healthy people. Its aim is to determine individuals at risk for a disease. Presymptomatic testing concerns mainly Mendelian diseases; an abnormal test result will lead to development of the disease in most cases in later life. Predictive testing concerns multifactorial or low penetrating Mendelian diseases; the test result will modify the risk of disorder occurring but with a much smaller degree of certainty.
Feingold
J
J
Laboratoire de recherches d'epidémiologie génétique-Inserm U155, université Paris VII, France.
D002869:Chromosome Aberrations; D030342:Genetic Diseases, Inborn / Q000145:classification / Q000175:diagnosis; D005820:Genetic Testing; D006801:Humans