title: Bronchoplastic procedures in malignant and nonmalignant disease: multivariable analysis of 144 cases.
abstract: OBJECTIVE
  We sought to analyze the experience with bronchoplastic procedures over a 7-year period and to determine putative prognostic factors for survival.
  
  
  METHODS
  From 1991 to 1997, 144 bronchoplastic procedures were performed for non-small cell lung cancer (n = 123), small cell lung cancer (n = 5), carcinoid tumor (n = 10), and metastases of extrathoracic malignant tumors (n = 6). There were 111 sleeve lobectomies, 17 bilobectomies, 4 lobectomies with carinal resection, 8 sleeve pneumonectomies, and 4 bronchotomies without parenchymal resection. Multivariable analysis included risk factors, such as age, sex, type of bronchoplastic procedure (bronchotomy, lobectomy, bilobectomy, or pneumonectomy), additional angioplasty, TNM staging, histology, radicality of resection, respiratory risk (forced expiratory volume in 1 second, percent predicted < 60), cardiovascular risk, and adjuvant therapy.
  
  
  RESULTS
  Overall 1- and 3-year survival was 72% and 52%, respectively. The overall 30-day mortality was 8.3% (5.4% for single sleeve lobectomies). Multivariable analysis demonstrated 4 risk factors for survival. High tumor stage, type of bronchoplastic procedure, impaired lung function, and presence of cardiovascular risk were associated with a poor outcome. Univariate analysis showed reduced survival in patients with sleeve pneumonectomies (1-year survival, 25%).
  
  
  CONCLUSIONS
  Bronchoplastic procedures for central tumors and sleeve pneumonectomies are associated with poor survival. Careful selection of these patients, as well as of patients with impaired lung function and cardiovascular risk factors, is mandatory.
authors.affiliation: Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria. adeheid.end@univie.ac.at
authors.forename: A
authors.initials: A
authors.lastname: End
authors.forename: P
authors.initials: P
authors.lastname: Hollaus
authors.forename: A
authors.initials: A
authors.lastname: Pentsch
authors.forename: W
authors.initials: W
authors.lastname: Brannath
authors.forename: D
authors.initials: D
authors.lastname: Janakiev
authors.forename: M R
authors.initials: MR
authors.lastname: Mueller
authors.forename: N
authors.initials: N
authors.lastname: Pridun
authors.forename: E
authors.initials: E
authors.lastname: Wolner
mesh_terms: D000328:Adult; D000368:Aged; D001980:Bronchi / Q000601:surgery*; D001982:Bronchial Diseases / Q000401:mortality / Q000601:surgery*; D001984:Bronchial Neoplasms / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000401:mortality / Q000601:surgery*; D008175:Lung Neoplasms / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011013:Pneumonectomy; D011183:Postoperative Complications / Q000453:epidemiology; D015996:Survival Rate