Noncaseating granulomatous disease in common variable immunodeficiency.
Patients with common variable immunodeficiency (CVID) are occasionally recognized to have a concurrent noncaseating granulomatous disease. The granulomatous disease (GD) associated with CVID shares many clinical properties typical of sarcoidosis. Some investigators speculate that the GD-CVID is actually sarcoidosis that is expressed atypically because of the patient's immunodeficiency. Clinical differences, however, have led other investigators to speculate that the GD-CVID is a distinct "sarcoid-like" granulomatous process.
Kanathur
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Department of Pulmonary Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, USA.
Byrd
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RP
Fields
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CL
Roy
T M
TM
D000368:Aged; D017074:Common Variable Immunodeficiency / Q000150:complications*; D015769:Granuloma, Respiratory Tract / Q000209:etiology*; D006801:Humans; D008297:Male