title: Quality of pharmacotherapy consultations provided by drug information centers in the United States.
abstract: We evaluated the performance of 116 U.S. drug information centers in responding to specific questions about drugs. The primary measures were correctness of responses and extent of probing for patient data. Questions addressed the effect of ranitidine on blood alcohol concentrations, the potential interaction between didanosine and dapsone, prevention of nonsteroidal antiinflammatory drug (NSAID)-induced peptic ulcers, and use of erythromycin for diabetic gastroparesis. The percentages of centers providing correct overall responses were 70% for the ranitidine question, 90% for the didanosine-dapsone question, 8% for the NSAID question, and 20% for the erythromycin question. For the three patient-specific questions, the percentages of centers eliciting vital patient data were 27% for the didanosine-dapsone question, 86% for the NSAID question, and 5% for the erythromycin question. In providing pharmacotherapy consultations, drug information centers generally failed to obtain pertinent patient data, thereby risking incorrect responses and inappropriate recommendations.
authors.affiliation: Department of Pharmacy, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892-1196, USA.
authors.forename: K A
authors.initials: KA
authors.lastname: Calis
authors.forename: D W
authors.initials: DW
authors.lastname: Anderson
authors.forename: D A
authors.initials: DA
authors.lastname: Auth
authors.forename: D A
authors.initials: DA
authors.lastname: Mays
authors.forename: N M
authors.initials: NM
authors.lastname: Turcasso
authors.forename: C C
authors.initials: CC
authors.lastname: Meyer
authors.forename: L R
authors.initials: LR
authors.lastname: Young
mesh_terms: D004346:Drug Information Services / Q000592:standards*; D004347:Drug Interactions; D004358:Drug Therapy; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D011787:Quality of Health Care; D012017:Referral and Consultation / Q000592:standards*; D014481:United States