title: On hypothetical bias and calibration in cost-benefit studies.
abstract: Despite a sound foundation in economic welfare theory, willingness to pay (WTP) has not been used as a measure of benefits in economic evaluations of health and health care to the same extent as in other fields. Some have suggested that this is due to non-economists' reluctance to placing dollar values on the benefits of health care. However, another potential reason could be uncertainties about the validity of the WTP measure. In this paper, we outline the bias problems with the WTP method, and specifically focus on hypothetical bias; i.e. whether the WTP from hypothetical elicitation methods overstates the real WTP or not. This is done by examining the literature in this field, with emphasis on economic experiments where there is a greater possibility for comparison. The findings are that hypothetical WTP in general significantly overestimates real WTP, but that calibration methods to reduce or eliminate this difference are currently being developed. We conclude that while the area is still very much under development, there seem to be reasons to view the use of cost-benefit analysis as a reasonable alternative to the more common cost-effectiveness analysis.
authors.affiliation: Program on Economic Evaluation of Medical Technology, Department of Health Policy and Management, Harvard School of Public Health, Boston, MA, USA. bengt.liljas@astrazeneca.com
authors.forename: B
authors.initials: B
authors.lastname: Liljas
authors.forename: K
authors.initials: K
authors.lastname: Blumenschein
mesh_terms: D002138:Calibration; D003362:Cost-Benefit Analysis / Q000379:methods*; D005382:Financing, Personal; D006292:Health Priorities / Q000191:economics*; D006801:Humans