title: Malignant intramuscular forearm tumor with overwhelming squamous element.
abstract: Squamous cell carcinoma (SCC) arising in the skeletal muscle is rare. A case of a 19-year-old female patient with an intramuscular forearm tumor showing a histopathologically overwhelming squamous element is presented. Microscopic examination revealed the classical features of SCC, including horn pearls, individual cell keratinization and intercellular bridge. A malignant spindle cell component was not detected. Neither evidence of another primary site nor skin lesion over the tumor was found and no metastatic lesion was detected in the 5 years since the appearance of the mass.
authors.affiliation: Department of Orthopaedic Surgery, Yamagata University School of Medicine, Yamagata, Japan. hoorui@med.id.yamagata-u.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Orui
authors.forename: M
authors.initials: M
authors.lastname: Yamakawa
authors.forename: A
authors.initials: A
authors.lastname: Ishikawa
authors.forename: T
authors.initials: T
authors.lastname: Tsuchiya
authors.forename: T
authors.initials: T
authors.lastname: Ogino
mesh_terms: D000199:Actins / Q000032:analysis / Q000235:genetics; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001365:Axilla; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D005542:Forearm / Q000473:pathology; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000601:surgery; D008279:Magnetic Resonance Imaging; D016685:Mitomycin / Q000008:administration & dosage; D019042:Muscle Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology* / Q000628:therapy; D015514:Oncogene Proteins, Fusion / Q000032:analysis / Q000235:genetics; D017663:Peplomycin / Q000008:administration & dosage; D012333:RNA, Messenger / Q000378:metabolism; D012334:RNA, Neoplasm / Q000032:analysis; D011877:Radionuclide Imaging; D020133:Reverse Transcriptase Polymerase Chain Reaction; D016896:Treatment Outcome; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D000199:Actins; D015514:Oncogene Proteins, Fusion; D012333:RNA, Messenger; D012334:RNA, Neoplasm; C116512:SYT-SSX fusion protein; D016685:Mitomycin; D017663:Peplomycin; D014750:Vincristine; D002945:Cisplatin