ras gene mutations in oral cancer in eastern India.
Oral tumor specimens (n = 50) from eastern Indian population were studied for the presence of mutations in the H-, K- and N-ras genes using selective oligodeoxynucleotide hybridization and restriction fragment length polymorphism analysis of polymerase chain reaction-amplified products. Mutations in H- and K-ras genes were observed at a frequency of 28 and 33%, respectively, whereas no N-ras mutation was noticed.
Das
N
N
Department of Biophysics, Molecular Biology and Genetics, University of Calcutta, India.
Majumder
J
J
DasGupta
U B
UB
D005260:Female; D011905:Genes, ras / Q000235:genetics*; D006801:Humans; D007194:India; D008297:Male; D009062:Mouth Neoplasms / Q000235:genetics*; D009154:Mutation / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length