Complications of photodynamic therapy in gastrointestinal disease.
The primary complications of photodynamic therapy of the esophagus include cutaneous photosensitivity and esophageal strictures. Atrial fibrillation and pleural effusion have been reported but appear to be rare or not clinically significant. Cutaneous photosensitivity can be minimized if the adequate precautions are taken to protect patients from sunlight exposure. Stricture formation may be decreased by proper dosimetry and avoiding multiple overlapping light applications.
Wang
K K
KK
Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Medical School, Mayo Clinic and Foundation, Rochester, MN 55905, USA.
Nijhawan
P K
PK
D002637:Chest Pain / Q000209:etiology*; D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects; D004940:Esophageal Stenosis / Q000209:etiology; D005767:Gastrointestinal Diseases / Q000188:drug therapy* / Q000473:pathology; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects / Q000473:pathology; D010778:Photochemotherapy / Q000009:adverse effects* / Q000379:methods; D017319:Photosensitizing Agents / Q000009:adverse effects*; D010996:Pleural Effusion / Q000209:etiology*
D017319:Photosensitizing Agents