Psittacosis with increased gammadelta T cells in bronchoalveolar lavage fluid.
Experience with two cases of psittacosis is described here in which the number of gammadelta T cell receptor-positive T lymphocytes (gammadelta T cell) in the bronchoalveolar lavage fluid was markedly increased (25.1 and 66.9%) and CD8+ T cells were also increased with reversal of the CD4/CD8 ratio. These values improved to the normal range along with recovery of their radiographical findings. The present findings suggest that gammadelta T cells may play an important role in protection from lung injury caused by Chlamydia psittaci infection.
Watanabe
H
H
The First Department of Internal Medicine, School of Medicine, Kyorin University, Tokyo, Japan.
Hayakawa
M
M
Igarashi
H
H
Tashimo
Y
Y
Saitoh
N
N
Takeda
H
H
Takayasu
S
S
Kawai
S
S
Kobayashi
H
H
D000328:Adult; D001992:Bronchoalveolar Lavage Fluid / Q000276:immunology*; D016516:CD4-CD8 Ratio; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D009956:Psittacosis / Q000000981:diagnostic imaging / Q000276:immunology*; D011859:Radiography; D016692:Receptors, Antigen, T-Cell, gamma-delta
D016692:Receptors, Antigen, T-Cell, gamma-delta