title: Bone growth factors.
abstract: Osteoblastic culture models, experimental, and clinical models have revealed that bone growth factors influence cellular activity. Growth factors including bone morphogenetic proteins, transforming growth factor beta, platelet-derived growth factor, insulin-like growth factors I and II, and acidic and basic fibroblast growth factors, are powerful tools for fracture healing and bone grafting. Understanding the role that bone growth factors play in bone repair is necessary to apply these factors in a clinical setting.
authors.affiliation: SpineCare Institute, Hospital for Special Surgery, New York, New York 10021, USA.
authors.forename: S N
authors.initials: SN
authors.lastname: Khan
authors.forename: M P
authors.initials: MP
authors.lastname: Bostrom
authors.forename: J M
authors.initials: JM
authors.lastname: Lane
mesh_terms: D000818:Animals; D001861:Bone Regeneration / Q000502:physiology*; D017102:Fracture Healing / Q000502:physiology*; D006133:Growth Substances / Q000502:physiology*; D006801:Humans; D010006:Osteoblasts / Q000502:physiology*
chemical_list: D006133:Growth Substances