Trypanosoma cruzi - the vector-parasite paradox.
Trypanosoma cruzi and the majority of its insect vectors (Hemiptera, Reduviidae, Triatominae) are confined to the Americas. But while recent molecular studies indicate a relatively ancient origin for the parasite ( approximately 65 million years ago) there is increasing evidence that the blood-sucking triatomine vectors have evolved comparatively recently (<5 mya). This review examines the evidence for these ideas, and attempts to reconcile the apparent paradox by suggesting that marsupial opossums (Didelphidae) may have played a role, not just as original reservoir hosts, but also as original vectors of the parasite.
Schofield
C
C
London School of Hygiene and Tropical Medicine, UK. cj.schoefield@wanadoo.fr
D000818:Animals; D006790:Host-Parasite Interactions; D007303:Insect Vectors / Q000469:parasitology*; D014225:Triatominae / Q000469:parasitology*; D014349:Trypanosoma cruzi / Q000502:physiology*