title: Allergic reactions to latex in myelodysplasia: a review of the literature.
abstract: Current research has identified clinically relevant allergens in natural latex. Children with myelodysplasia are especially considered to be at risk for the development of immunoglobulin E-mediated hypersensitivity, which can lead to life-threatening intraoperative anaphylaxis. A careful medical history is mandatory to identify patients who might be predisposed to anaphylactic reactions. Preventive measures involve primarily the avoidance of latex contact at home and in hospitals for all patients with myelodysplasia. The effectiveness of additional pharmacologic prophylaxis has to be determined further.
authors.affiliation: Department of Orthopaedic Surgery (RKU), University of Ulm, Germany.
authors.forename: K P
authors.initials: KP
authors.lastname: Günther
authors.forename: M
authors.initials: M
authors.lastname: Nelitz
authors.forename: K
authors.initials: K
authors.lastname: Parsch
authors.forename: W
authors.initials: W
authors.lastname: Puhl
mesh_terms: D000293:Adolescent; D002648:Child; D002927:Cimetidine / Q000627:therapeutic use; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000188:drug therapy; D007073:Immunoglobulin E / Q000276:immunology; D007431:Intraoperative Complications / Q000453:epidemiology / Q000517:prevention & control*; D020315:Latex Hypersensitivity / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D009436:Neural Tube Defects / Q000276:immunology* / Q000601:surgery; D011237:Predictive Value of Tests; D012307:Risk Factors
chemical_list: D006635:Histamine H2 Antagonists; D007073:Immunoglobulin E; D002927:Cimetidine