[Assessment of therapeutic efficacy, an essential step in evidence-based medicine].
Evidence-based medicine relies on the results from clinical trials. We will describe the various modes of expression of the results (absolute risk reduction, relative risk reduction, odds ratios, number needed to treat to avoid one event,...) and we will insist upon the clinical significance and the pitfalls in the interpretation of these various indices of therapeutic efficacy.
Scheen
A J
AJ
Département de Médecine, CHU Sart Tilman, Liège.
D002986:Clinical Trials as Topic; D019317:Evidence-Based Medicine; D006801:Humans; D016017:Odds Ratio; D018570:Risk Assessment; D016896:Treatment Outcome