Genomic structure and chromosome location of the mouse RelA p65 gene (Rela).
The RelA (p65) subunit of transcription factor NF-kappaB plays a critical role in development, and rela(-/-) knockout mice die in utero from massive liver apoptosis. Only partial sequences of the mouse Rela gene are available. We have determined the genomic structure of mouse Rela and promoter, and have mapped the gene to chromosome 19B1-3.
Lemmer
E R
ER
Laboratory of Experimental Carcinogenesis, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Welch
J L
JL
Tsai
T
T
Keck-Waggoner
C L
CL
Huh
C
C
Zimonjic
D B
DB
Popescu
N C
NC
Thorgeirsson
S S
SS
D000818:Animals; D001483:Base Sequence; D002871:Chromosome Banding; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics; D003001:Cloning, Molecular; D005091:Exons / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007438:Introns / Q000235:genetics*; D051379:Mice; D008969:Molecular Sequence Data; D016328:NF-kappa B / Q000235:genetics*; D020161:Physical Chromosome Mapping; D011401:Promoter Regions, Genetic / Q000235:genetics; D051996:Transcription Factor RelA
D016328:NF-kappa B; D051996:Transcription Factor RelA