title: Radiation-associated xanthomatous meningioma in a child.
abstract: Radiation-associated meningioma in a child is rare. We report a case of xanthomatous meningioma, a rare subtype even in the adult population, which occurred in a 10-year-old boy who had undergone irradiation therapy for ependymoma at the age of 2 years. Histological examination of the tumor revealed a mixture of meningothelial cells and abundant foamy xanthomatous cells, with no apparent atypical cellular features. Xanthomatous meningioma associated with therapeutic high-dose irradiation in a child has not yet been documented. Immunohistochemical studies and the clinical course are evaluated with a review of the literature.
authors.affiliation: Department of Pathology, Kanagawa Children Medical Center, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Ijiri
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Hara
authors.forename: K
authors.initials: K
authors.lastname: Sekido
mesh_terms: D001932:Brain Neoplasms / Q000532:radiotherapy; D002648:Child; D016371:Cranial Irradiation / Q000009:adverse effects*; D019583:Dose Fractionation, Radiation; D004806:Ependymoma / Q000532:radiotherapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D008579:Meningioma / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis / Q000473:pathology*; D012086:Reoperation