[Treatment of chronic immune-mediated polyneuropathies. State of the art and perspectives].
Chronic immune-mediated polyneuropathies encompass chronic inflammatory demyelinating polyneuropathies, polyneuropathies associated with monoclonal gammopathy and multifocal motor neuropathy with persistent conduction blocks. Their diagnosis is made on clinical, electrophysiological and sometimes immunochemical and pathological criteria. The efficacy of short-term treatments (corticosteroids, plasma exchanges, intravenous immunoglobulins) depends on the type of the polyneuropathy, but these treatments may sometimes lead to prolonged improvement. The efficacy of long-term treatments needs further evaluation.
Léger
J M
JM
Fédération de Neurologie, Bâtiment Mazarin, Hôpital de la Salpêtrière, 47, boulevard de l'Hôpital, Paris.
Chassande
B
B
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000276:immunology; D002908:Chronic Disease; D003711:Demyelinating Diseases / Q000276:immunology / Q000628:therapy; D004568:Electrodiagnosis; D006801:Humans; D006942:Hypergammaglobulinemia / Q000628:therapy; D007154:Immune System Diseases / Q000628:therapy*; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D016472:Motor Neuron Disease / Q000276:immunology; D009431:Neural Conduction / Q000276:immunology; D010951:Plasma Exchange; D011115:Polyneuropathies / Q000276:immunology* / Q000628:therapy
D000305:Adrenal Cortex Hormones; D000911:Antibodies, Monoclonal; D016756:Immunoglobulins, Intravenous