title: [Unconventional treatment of severe heart failure in the elderly].
abstract: In the elderly, congestive heart failure is common and associated with significant morbidity and mortality. Comprehensive management of heart failure improves functional status and decreases mortality. Diuretics remain the mainstay in treating congestive heart failure. However, some patients are resistant to diuretics. This is a serious problem as it seems to represent a final manifestation of congestive heart failure. In an 85-year-old woman diuretic resistance was recognized as the cause of failure of conventional diuretic therapy. When the dose of furosemide was rapidly increased from 120 mg per os to 1000 mg i.v. within 4 days, diuresis began and there was dramatic improvement in her condition. The dose was then gradually decreased until a conventional maintenance dose of 200 mg/day per os was reached. This dose was sufficient to keep her heart failure under control.
authors.affiliation: Geriatric Medical Center, Natanya.
authors.forename: Z
authors.initials: Z
authors.lastname: Fidelman
authors.forename: Z
authors.initials: Z
authors.lastname: Korshun
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004231:Diuresis; D004232:Diuretics / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005665:Furosemide / Q000627:therapeutic use*; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans
chemical_list: D004232:Diuretics; D005665:Furosemide