Breast cancer in vivo: contrast enhancement with thermoacoustic CT at 434 MHz-feasibility study.
The authors performed thermoacoustic computed tomography (CT) with 434-MHz radio waves in five patients with documented breast cancer. Three of the patients underwent imaging before chemotherapy was initiated and two at the conclusion of their primary chemotherapy. In the former three patients, thermoacoustic CT demonstrated contrast enhancement in the region of the tumor. In the latter two patients, no contrast enhancement was seen, and pathologic examination after surgical resection of the area of original tumor confirmed complete remission of disease.
Kruger
R A
RA
Department of Radiology, Indiana University School of Medicine, Clinical Bldg 157, 541 Clinical Dr, Indianapolis, IN 46202-5111, USA. rkruger@iupui.edu
Miller
K D
KD
Reynolds
H E
HE
Kiser
W L
WL
Reinecke
D R
DR
Kruger
G A
GA
D000162:Acoustics; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D011846:Radio Waves; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*