Evidence of abnormal esophageal motility in syndrome X by radionuclide esophageal transit test.
In 30 patients with syndrome X, esophageal motility was evaluated by radionuclide esophageal transit test (RETT). Esophageal motility measurements included esophageal mean transit time (MTT), residual fraction (RF), and retrograde index (RI). In comparison with 25 age- and sex-matched healthy volunteers, 66% of the patients with syndrome X had abnormal RETT findings including 50% of cases with longer MTT, 50% of cases with higher RF, and 33% of cases with higher RI. In addition, the mean values of MTT, RF, and RI in patients with syndrome X were significantly higher than those of healthy volunteers. We conclude that abnormal esophageal motility occurred in a large portion of syndrome X patients based on an simple and noninvasive RETT.
Kao
C H
CH
Department of Nuclear Medicine, Taichung Veterans General Hospital, Taichung, Taiwan. kao@vghtc.gov.tw
Hsieh
J F
JF
Tsai
C S
CS
Ho
Y J
YJ
Lee
J K
JK
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D015154:Esophageal Motility Disorders / Q000000981:diagnostic imaging / Q000209:etiology*; D004947:Esophagus / Q000000981:diagnostic imaging*; D005260:Female; D005772:Gastrointestinal Transit; D006801:Humans; D008297:Male; D017566:Microvascular Angina / Q000150:complications*; D008875:Middle Aged; D015609:Organotechnetium Compounds; D010833:Phytic Acid; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals
D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D010833:Phytic Acid