title: Predictors of failure of nasal continuous positive airway pressure in treatment of preterm infants with respiratory distress syndrome.
abstract: A case-control study was carried out on 97 consecutive preterm (< 37 weeks) infants to determine predictors associated with failure of nasal continuous positive airway pressure (CPAP) in the treatment of respiratory distress syndrome (RDS). Logistic regression analysis showed that only three risk factors were significantly associated with failed CPAP. These were: moderate or severe RDS (odds ratio: 5.9; 95 per cent confidence interval (CI): 2.2-16.0); septicemia during CPAP therapy (OR: 8.8; 95 per cent: CI 1.5-50.7); and pneumothorax during CPAP therapy (odds ratio: 6.9; 95 per cent: CI 1.1-41.7).
authors.affiliation: Department of Paediatrics, Universiti Kebangsaan, Malaysia. nyboo@hukln.ukm.my
authors.forename: N Y
authors.initials: NY
authors.lastname: Boo
authors.forename: A L
authors.initials: AL
authors.lastname: Zuraidah
authors.forename: N L
authors.initials: NL
authors.lastname: Lim
authors.forename: M A
authors.initials: MA
authors.lastname: Zulfiqar
mesh_terms: D001034:Apgar Score; D016022:Case-Control Studies; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D016015:Logistic Models; D011030:Pneumothorax / Q000209:etiology; D011175:Positive-Pressure Respiration; D011237:Predictive Value of Tests; D012127:Respiratory Distress Syndrome, Newborn / Q000150:complications / Q000628:therapy*; D012307:Risk Factors; D018805:Sepsis / Q000209:etiology; D017211:Treatment Failure