title: The impact of media composition and petite mutation on the longevity of a polyploid brewing yeast strain.
abstract: Ageing in Saccharomyces cerevisiae is a finite phenomenon, determined by replicative, rather than chronological lifespan. Yeast physiological condition is known to influence industrial fermentation performance, however, until recently cellular senescence has not been considered as a brewing yeast stress factor. A polyploid lager yeast (BB11) and a brewery isolate, exhibiting petite mutation were analysed for longevity. It was observed that mitochondrial deficiency induced a reduction in lifespan. In addition, replicative capacity was perceived to be dependent on environmental conditions.
authors.affiliation: School of Biological and Molecular Sciences, Oxford Brookes University, Oxford, UK.
authors.forename: C D
authors.initials: CD
authors.lastname: Powell
authors.forename: D E
authors.initials: DE
authors.lastname: Quain
authors.forename: K A
authors.initials: KA
authors.lastname: Smart
mesh_terms: D003470:Culture Media; D008928:Mitochondria / Q000235:genetics*; D009154:Mutation; D011123:Polyploidy; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000502:physiology*
chemical_list: D003470:Culture Media