title: The classification of personality disorders should be rooted in biology.
abstract: As scientific classifications develop over time, they become based less on observations and more on mechanisms. Existing dimensional schema are limited by being overly broad and by being rooted in self-report rather than theory. Future models should be consistent with a scientific hierarchy, leading to a bottom-up classification of traits and disorders, linking molecular genetics, neurobiological markers, and temperamental variations.
authors.affiliation: Department of Psychiatry, McGill University, Montréal, Québec, Canada. cxjp@musica.mcgill.ca
authors.forename: J
authors.initials: J
authors.lastname: Paris
mesh_terms: D020022:Genetic Predisposition to Disease; D006801:Humans; D010554:Personality Disorders / Q000145:classification* / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology; D011569:Psychiatric Status Rating Scales; D011603:Psychophysiology; D012307:Risk Factors