title: Monitoring the effectiveness of preventive interventions using progression of coronary calcification with electron beam tomography.
abstract: Angiographic studies have demonstrated that progression of coronary artery disease can be slowed and in some cases regression obtained with appropriate medical therapies. However, coronary angiography is invasive and expensive. Detection of coronary artery calcification, a marker of atherosclerotic disease, with electron beam tomography imaging is achieved non-invasively and at a much lower cost. Therefore, this technology provides an opportunity to serially monitor the clinical effectiveness of medical therapy for coronary artery disease and could be useful for development of new therapies for atherosclerosis.
authors.affiliation: EBT Research Foundation, Nashville, Tennessee, USA. praggi@attglobal.net
authors.forename: P
authors.initials: P
authors.lastname: Raggi
mesh_terms: D002114:Calcinosis / Q000000981:diagnostic imaging / Q000517:prevention & control*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000517:prevention & control*; D018450:Disease Progression; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D008991:Monitoring, Physiologic / Q000379:methods*; D014057:Tomography, X-Ray Computed
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors