title: Nuclear maturation inhibitors in Bufo arenarum oocytes.
abstract: In Bufo arenarum, as in other amphibian species, nuclear maturation--characterized by germinal vesicle breakdown (GVBD) and meiosis resumption--is induced by progesterone. Seasonal variations in the sensitivity to progesterone were observed in Bufo arenarum oocytes. The gonadotropin FSH and drugs such as dbcAMP and xanthine did not affect nuclear maturation per se, although they acted as negative modulators of progesterone-induced nuclear maturation. Similar results to FSH in nuclear maturation were obtained with 17 beta-estradiol.
authors.affiliation: Instituto de Biología, Universidad Nacional de Tucumán, CONICET, S. M. de Tucumán, Argentina.
authors.forename: I R
authors.initials: IR
authors.lastname: de Romero
authors.forename: M B
authors.initials: MB
authors.lastname: de Atenor
authors.forename: A H
authors.initials: AH
authors.lastname: Legname
mesh_terms: D000818:Animals; D002022:Bufo arenarum; D002467:Cell Nucleus / Q000187:drug effects / Q000502:physiology*; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D008540:Meiosis / Q000502:physiology; D009865:Oocytes / Q000166:cytology* / Q000187:drug effects / Q000502:physiology*; D011374:Progesterone / Q000494:pharmacology*
chemical_list: D011374:Progesterone; D004958:Estradiol