title: [Necrotizing soft tissue infection].
abstract: The dramatic course of necrotizing soft tissue infection represents a medical emergency, since it is limb- and life-threatening. Most necrotizing soft tissue infections are caused by mixed aerobic and anaerobic Gram-negative and Gram-positive organisms. Most case have been reported in immuno-compromised hosts after penetrating trauma or surgery. We describe a unique series of cases of necrotizing soft tissue infection. The mainstay of treatment is early and daily debridement of devitalized tissue and broad-spectrum antibiotics. Hyperbaric oxygen therapy should be considered.
authors.forename: E
authors.initials: E
authors.lastname: Rath
authors.forename: I
authors.initials: I
authors.lastname: Shelef
authors.forename: E
authors.initials: E
authors.lastname: Avinoah
authors.forename: Y
authors.initials: Y
authors.lastname: Lichtman
authors.forename: O
authors.initials: O
authors.lastname: Levy
authors.forename: D
authors.initials: D
authors.lastname: Atar
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D003646:Debridement; D019115:Fasciitis, Necrotizing / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008875:Middle Aged; D018461:Soft Tissue Infections / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*
chemical_list: D000900:Anti-Bacterial Agents