title: Options for repair of a bicuspid aortic valve and ascending aortic aneurysm.
abstract: BACKGROUND
  Intrinsic abnormality of the aortic wall may explain the association of bicuspid aortic valves with ascending aortic aneurysms. Separate valve and graft repair of such lesions, rather than composite valve graft replacement, is more straightforward but leaves potentially abnormal sinuses behind.
  
  
  METHODS
  Between January 1985 and January 1998, 45 patients underwent separate valve and graft (n = 27) or composite valve graft (n = 18) for an ascending aortic aneurysm and bicuspid aortic valve. Perioperative events and late results were compared.
  
  
  RESULTS
  Patients undergoing separate valve and graft were older (mean age, 60 +/- 13 vs 42 +/- 12 years, p < 0.001) and were more likely to have purely stenotic (48% vs 6%, p = 0.003) than purely regurgitant (11% vs 72%, p < 0.001) disease. They were also more likely to require concomitant coronary artery bypass grafting (56% vs 6%, p = 0.001). There were no significant differences in operative risk and no known late complications related to recurrent aneurysms.
  
  
  CONCLUSIONS
  Root replacement with a composite valve graft can be accomplished with low operative risk and is the first choice for repair of this lesion. Separate valve and graft repair, however, yields satisfactory early and late results and remains an acceptable option, especially when the coronary ostea are not displaced or when concomitant procedures must be performed.
authors.affiliation: Department of Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA. sundt@msnotes.wustl.edu
authors.forename: T M
authors.initials: TM
authors.lastname: Sundt
authors.forename: B N
authors.initials: BN
authors.lastname: Mora
authors.forename: M R
authors.initials: MR
authors.lastname: Moon
authors.forename: M S
authors.initials: MS
authors.lastname: Bailey
authors.forename: M K
authors.initials: MK
authors.lastname: Pasque
authors.forename: W A
authors.initials: WA
authors.lastname: Gay
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001014:Aortic Aneurysm / Q000150:complications / Q000601:surgery*; D001021:Aortic Valve / Q000002:abnormalities* / Q000637:transplantation*; D001022:Aortic Valve Insufficiency / Q000601:surgery; D001024:Aortic Valve Stenosis / Q000601:surgery; D001026:Coronary Artery Bypass; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies