title: [Acid-base balance in ulcer patients].
abstract: Acid-base balance was studied in 60 ulcer patients in exacerbation and after treatment with losek and blockers of H2-histamine receptors. In exacerbation, all the patients had acidosis of metabolic or respiratory type. Losek changed blood pH insignificantly, and one acidosis type changed for the other. A single ranitidin dose shifted pH to alkalosis in healthy subjects while ulcer patients given famotidine restored acid-base balance. The latter is shown to correlate with gastric secretion of bicarbonates. Acidosis may contribute to exacerbation of ulcer.
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Malov
authors.forename: T G
authors.initials: TG
authors.lastname: Ivashkina
authors.forename: A N
authors.initials: AN
authors.lastname: Kulikov
authors.forename: A P
authors.initials: AP
authors.lastname: Rossolovich
mesh_terms: D000136:Acid-Base Equilibrium / Q000502:physiology*; D000328:Adult; D004573:Electrolytes / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D010437:Peptic Ulcer / Q000175:diagnosis* / Q000378:metabolism*
chemical_list: D004573:Electrolytes