title: Use of recombinant-hirudin in pulmonary thromboendarterectomy.
abstract: A patient with chronic thromboembolic pulmonary hypertension and heparin-induced thrombocytopenia successfully underwent pulmonary thromboendarterectomy with circulatory arrest, using recombinant hirudin as an alternative anticoagulant to heparin. Techniques for administration as well as monitoring of this drug's effects are discussed.
authors.affiliation: Department of Surgery, University of Ottawa, Ontario, Canada. frubens@ottawaheart.ca
authors.forename: F D
authors.initials: FD
authors.lastname: Rubens
authors.forename: M
authors.initials: M
authors.lastname: Sabloff
authors.forename: P S
authors.initials: PS
authors.lastname: Wells
authors.forename: M
authors.initials: M
authors.lastname: Bourke
mesh_terms: D002315:Cardiopulmonary Bypass; D004691:Endarterectomy; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006629:Hirudins / Q000008:administration & dosage*; D006801:Humans; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000601:surgery*; D011994:Recombinant Proteins / Q000008:administration & dosage
chemical_list: D005343:Fibrinolytic Agents; D006629:Hirudins; D011994:Recombinant Proteins