title: Effect of Kombucha tea on chromate(VI)-induced oxidative stress in albino rats.
abstract: The effect of Kombucha tea (KT) on oxidative stress induced changes in rats subjected to chromate treatment are reported. KT feeding alone did not show any significant change in malondialdehyde (MDA) and reduced glutathione (GSH) levels, but did enhance humoral response and delayed type of hypersensitivity (DTH) response appreciably over control animals. Chromate treatment significantly enhanced plasma and tissue MDA levels, decreased DTH response considerably, enhanced glutathione peroxidase and catalase activities; however, no change in GSH, superoxide dismutase and antibody titres was noticed. KT feeding completely reversed the chromate-induced changes. These results show that Kombucha tea has potent anti-oxidant and immunopotentiating activities.
authors.affiliation: Defence Institute of Physiology and Allied Sciences, Lucknow Road, Timarpur, 110054, Delhi, India.
authors.forename: M
authors.initials: M
authors.lastname: Sai Ram
authors.forename: B
authors.initials: B
authors.lastname: Anju
authors.forename: T
authors.initials: T
authors.lastname: Pauline
authors.forename: P
authors.initials: P
authors.lastname: Dipti
authors.forename: A K
authors.initials: AK
authors.lastname: Kain
authors.forename: S S
authors.initials: SS
authors.lastname: Mongia
authors.forename: S K
authors.initials: SK
authors.lastname: Sharma
authors.forename: B
authors.initials: B
authors.lastname: Singh
authors.forename: R
authors.initials: R
authors.lastname: Singh
authors.forename: G
authors.initials: G
authors.lastname: Ilavazhagan
authors.forename: D
authors.initials: D
authors.lastname: Kumar
authors.forename: W
authors.initials: W
authors.lastname: Selvamurthy
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D000975:Antioxidants / Q000494:pharmacology*; D001628:Beverages / Q000032:analysis*; D002840:Chromates / Q000037:antagonists & inhibitors / Q000633:toxicity*; D004912:Erythrocytes / Q000276:immunology; D005285:Fermentation; D005978:Glutathione / Q000097:blood; D006968:Hypersensitivity, Delayed / Q000276:immunology; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D018384:Oxidative Stress / Q000187:drug effects*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D000975:Antioxidants; D002840:Chromates; D008315:Malondialdehyde; D005978:Glutathione