Case report. Primary cutaneous histoplasmosis in an immunosuppressed patient.
A case of cutaneous histoplasmosis is reported in an 80-year-old man with rheumatoid arthritis who had been treated with steroid therapy for 15 years. The patient developed a large ulcerative lesion on the back of the left hand and on the distal third of the left dorsal forearm after a slight trauma. Diagnosis was based on histological and mycological examination. Systemic involvement was not found. The lesions healed after 2 months of therapy with 100 mg day-1 fluconazole, confirmed at follow-up 1 year later.
Romano
C
C
Castelli
A
A
Laurini
L
L
Massai
L
L
D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology*; D015725:Fluconazole / Q000627:therapeutic use; D005500:Follow-Up Studies; D005542:Forearm; D006225:Hand; D006658:Histoplasma / Q000302:isolation & purification*; D006660:Histoplasmosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D012867:Skin / Q000382:microbiology
D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D017964:Itraconazole; D015725:Fluconazole; D008775:Methylprednisolone