title: Tandem Cyclization of Alkynylmetals Bearing a Remote Leaving Group via Cycloalkylidene Carbenes.
abstract: Treatment of terminal alkynes bearing a remote leaving group with MNR(2) (M = Li, Na, K) gives bicyclo[n.3.0]-1-alkenes (n = 3, 4). The tandem cyclization proceeds through a mechanism involving exo-cyclization of an alkynylmetal intermediate and intramolecular C-H insertion of the resulting carbenoid.
authors.affiliation: Department of Chemistry, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku Kyoto 606-8585, Japan.
authors.initials: T
authors.lastname: Harada
authors.initials: T
authors.lastname: Fujiwara
authors.initials: K
authors.lastname: Iwazaki
authors.initials: A
authors.lastname: Oku