title: Prognosis related to staging systems for chronic lymphocytic leukemia.
abstract: BACKGROUND
  Chronic lymphocytic leukemia (CLL) is a clonal lymphoproliferative disorder, characterized by B lymphocytic proliferation. CLL is the most frequent adult leukemia in Western countries, accounting for 25 to 30% of all white leukemic patients.
  
  
  OBJECTIVE
  To evaluate clinical and staging characteristics in prognosis of chronic lymphocytic leukemia.
  
  
  METHODS
  Evaluation of clinical-staging data.
  
  
  METHODS
  Universidade Federal de São Paulo - Escola Paulista de Medicina / Universidade de Alfenas.
  
  
  METHODS
  73 patients diagnosed from 1977 to 1994.
  
  
  METHODS
  Sex, ethnic origin, age, lymphadenopathy, splenomegaly, hepatomegaly, three or more areas of lymphoid enlargement, hemoglobin (g/dl), lymphocytes/mm3, Platelets/mm3
  
  
  RESULTS
  Mean survival of patients was 76 months, median age was 65 years, ranging from 33 to 87. Forty-four patients (60.3%) were male and 29 (39.7%) female.
  
  
  CONCLUSIONS
  The Binet system determined a better prognosis than Rai.
authors.affiliation: Division of Hematology, Universidade de Alfenas, Minas Gerais, Brazil.
authors.forename: J R
authors.initials: JR
authors.lastname: de Faria
authors.forename: J S
authors.initials: JS
authors.lastname: de Oliveira
authors.forename: R M
authors.initials: RM
authors.lastname: Delbone de Faria
authors.forename: M R
authors.initials: MR
authors.lastname: Silva
authors.forename: S
authors.initials: S
authors.lastname: Goihman
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
authors.forename: J
authors.initials: J
authors.lastname: Kerbauy
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000401:mortality / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D017741:Survivors