Vertebrate mesendoderm induction and patterning.
Many of the key molecular events underlying the induction and patterning of the vertebrate mesoderm and endoderm have recently been elucidated. T-box transcription factors and TGF-beta and Wnt signaling pathways play crucial roles in the initial induction of the mesendoderm and the subdivision of the posterior mesoderm into rostral and caudal domains.
Kimelman
D
D
Department of Biochemistry, Center for Developmental Biology, University of Washington, Seattle 98195-7350, USA. kimelman@u.washington.edu
Griffin
K J
KJ
D000818:Animals; D019521:Body Patterning / Q000502:physiology*; D004627:Embryonic Induction / Q000502:physiology*; D004707:Endoderm / Q000502:physiology*; D008648:Mesoderm / Q000502:physiology*; D014714:Vertebrates / Q000196:embryology; D014981:Xenopus / Q000196:embryology; D015027:Zebrafish / Q000196:embryology