[Acid-base balance in ulcer patients].
Acid-base balance was studied in 60 ulcer patients in exacerbation and after treatment with losek and blockers of H2-histamine receptors. In exacerbation, all the patients had acidosis of metabolic or respiratory type. Losek changed blood pH insignificantly, and one acidosis type changed for the other. A single ranitidin dose shifted pH to alkalosis in healthy subjects while ulcer patients given famotidine restored acid-base balance. The latter is shown to correlate with gastric secretion of bicarbonates. Acidosis may contribute to exacerbation of ulcer.
Malov
Iu S
IuS
Ivashkina
T G
TG
Kulikov
A N
AN
Rossolovich
A P
AP
D000136:Acid-Base Equilibrium / Q000502:physiology*; D000328:Adult; D004573:Electrolytes / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D010437:Peptic Ulcer / Q000175:diagnosis* / Q000378:metabolism*
D004573:Electrolytes