Possible malignant transformation of benign lymphoepithelial parotid lesions in human immunodeficiency virus-infected patients: report of three cases.
Benign lymphoepithelial parotid lesions (BLL) are intraparotid pathological changes that are commonly thought to be an early manifestation of human immunodeficiency virus (HIV) infection. It is not well known whether BLL may undergo malignant transformation into B cell lymphoma and may therefore be a sort of precancerous lesion. We report 3 cases of possible malignant transformation of BLL in HIV-infected patients.
Del Bono
V
V
I Clinica Malattie Infettive, DISEM, Università di Genova, 16132 Genova, Italy. bico001@pn.itnet.it
Pretolesi
F
F
Pontali
E
E
Martinoli
C
C
Bassetti
M
M
Mazzarello
G
G
Chiaramondia
M
M
Derchi
L E
LE
Bassetti
D
D
D000328:Adult; D002471:Cell Transformation, Neoplastic; D005260:Female; D015658:HIV Infections / Q000473:pathology*; D006801:Humans; D008221:Lymphoid Tissue / Q000473:pathology* / Q000821:virology; D016483:Lymphoma, AIDS-Related / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010305:Parotid Diseases / Q000473:pathology* / Q000821:virology; D010306:Parotid Gland / Q000473:pathology