The immunology of malaria infection.
As global malaria mortality increases the urgency for vaccine development, analysis of immune responses in naturally exposed populations is providing clues to the nature of protective immunity. Recently, sophisticated immune evasion strategies adopted by the parasite have been analysed at the molecular level. More immunogenic vaccination strategies have been identified, providing renewed optimism that effective malaria control through vaccination should be feasible.
Plebanski
M
M
Vaccine Development and Infectious Diseases Unit, The Austin Research Institute, Heidelberg, VA 3084, Australia. mplebans@ari.unimelb.edu.au
Hill
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AV
D000818:Animals; D019353:Endemic Diseases; D004912:Erythrocytes / Q000276:immunology; D006412:Hematopoietic Stem Cells / Q000276:immunology; D006801:Humans; D008288:Malaria / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control