Photodynamic therapy of Barrett's esophagus.
Photodynamic therapy seems to be able to control high-grade dysplasia within Barrett's esophagus about 80% of the time. Long-term results are not available, but the treatment is promising. Given the success with surgical intervention, however, use of photodynamic therapy should be reserved for nonsurgical candidates at the current time. The complications that occur with photodynamic therapy are not trivial and must be weighed against the potential benefits.
Wang
K K
KK
Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Medical School, Mayo Clinic and Foundation, Rochester, MN 55905, USA.
D000622:Aminolevulinic Acid / Q000008:administration & dosage / Q000627:therapeutic use; D001471:Barrett Esophagus / Q000188:drug therapy*; D004945:Esophagoscopy; D005336:Fiber Optic Technology; D017324:Hematoporphyrin Derivative / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007275:Injections, Intravenous; D053685:Laser Therapy; D010778:Photochemotherapy / Q000379:methods; D017319:Photosensitizing Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D011524:Protoporphyrins / Q000008:administration & dosage / Q000627:therapeutic use
D017319:Photosensitizing Agents; D011524:Protoporphyrins; D017324:Hematoporphyrin Derivative; D000622:Aminolevulinic Acid; C028025:protoporphyrin IX