title: Delayed cerebral radiation necrosis occurring twice at different regions and times in a patient with a metastatic brain tumour.
abstract: No case of histopathologically confirmed delayed cerebral radiation necrosis (DCRN) that occurred twice at different regions and times in the same patient has been previously reported. We present a patient with such a rare clinical course and who is surviving long-term (over 13 years) with a history of a distant metastasis of a malignant tumour. To diagnose DCRN preoperatively was very difficult. However, surgical extirpation seemed to be effective for DCRN. The patient is still in a good performance status after surgery.
authors.affiliation: Department of Neurosurgery, Hiroshima Prefectural Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kawamoto
authors.forename: K
authors.initials: K
authors.lastname: Kiya
authors.forename: K
authors.initials: K
authors.lastname: Yuki
authors.forename: T
authors.initials: T
authors.lastname: Uozumi
mesh_terms: D001921:Brain / Q000473:pathology* / Q000528:radiation effects*; D001927:Brain Diseases / Q000209:etiology*; D001932:Brain Neoplasms / Q000532:radiotherapy* / Q000556:secondary* / Q000601:surgery; D002277:Carcinoma / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D009336:Necrosis; D011832:Radiation Injuries / Q000150:complications* / Q000473:pathology; D012008:Recurrence; D013997:Time Factors; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery