title: Reduction in incidence of severe paracetamol poisoning.
abstract: We report substantial reductions in the frequency of severe paracetamol hepatotoxicity locally and nationally after legislative limitations on its sale. These reductions were not explained by changes in referral patterns or use of N-acetylcysteine.
authors.forename: M I
authors.initials: MI
authors.lastname: Prince
authors.forename: S H
authors.initials: SH
authors.lastname: Thomas
authors.forename: O F
authors.initials: OF
authors.lastname: James
authors.forename: M
authors.initials: M
authors.lastname: Hudson
mesh_terms: D000082:Acetaminophen / Q000506:poisoning*; D000111:Acetylcysteine / Q000008:administration & dosage; D000328:Adult; D018712:Analgesics, Non-Narcotic / Q000506:poisoning*; D056486:Chemical and Drug Induced Liver Injury; D005260:Female; D016166:Free Radical Scavengers / Q000008:administration & dosage; D006801:Humans; D015994:Incidence; D007880:Legislation, Drug; D008107:Liver Diseases / Q000628:therapy; D008297:Male; D011041:Poisoning / Q000145:classification / Q000453:epidemiology / Q000517:prevention & control; D012720:Severity of Illness Index; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D018712:Analgesics, Non-Narcotic; D016166:Free Radical Scavengers; D000082:Acetaminophen; D000111:Acetylcysteine