Multiplexed genotyping of beta-globin variants from PCR-amplified newborn blood spot DNA by hybridization with allele-specific oligodeoxynucleotides coupled to an array of fluorescent microspheres.
Colinas
R J
RJ
Division of Genetic Disorders, Wadsworth Center, New York State Department of Health, Albany, NY 12201-0509, USA. colinas@wadsworth.org
Bellisario
R
R
Pass
K A
KA
D000483:Alleles; D001800:Blood Specimen Collection; D004247:DNA / Q000097:blood* / Q000235:genetics; D005456:Fluorescent Dyes; D005914:Globins / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008863:Microspheres; D015997:Neonatal Screening / Q000379:methods*; D009838:Oligodeoxyribonucleotides; D016133:Polymerase Chain Reaction
D005456:Fluorescent Dyes; D009838:Oligodeoxyribonucleotides; D005914:Globins; D004247:DNA