title: Upper airway resistance syndrome and its treatment.
abstract: Although upper airway resistance syndrome (UARS) is being recognized by a growing number of specialists, its prevalence remains unknown. UARS is associated with nocturnal and daytime complaints and oro-naso-maxillo-mandibular signs. Spectrum analysis of the nocturnal sleep EEG from the central leads indicates significant differences in absolute power in the 12-14 Hz and the 7-9 Hz bands of UARS patients compared to controls. The 0.5-2.0 Hz band also appears to be involved when analyses performed on matched controls are compared to results obtained in subjects treated with nasal CPAP. Several treatment avenues--nasal CPAP, dental devices, surgical procedures, and radiofrequency thermal ablation--have been used for the treatment of UARS. The number of subjects treated have been too low and the protocols too limited to arrive at appropriate outcome recommendations, but many of the approaches have shown positive results, suggesting the possibility of several treatment avenues.
authors.affiliation: Stanford University Sleep Disorders Clinic and Research Center, CA 94305, USA.
authors.forename: C
authors.initials: C
authors.lastname: Guilleminault
authors.forename: Y D
authors.initials: YD
authors.lastname: Kim
authors.forename: L
authors.initials: L
authors.lastname: Palombini
authors.forename: K
authors.initials: K
authors.lastname: Li
authors.forename: N
authors.initials: N
authors.lastname: Powell
mesh_terms: D004569:Electroencephalography; D006801:Humans; D010349:Patient Compliance; D011175:Positive-Pressure Respiration / Q000379:methods*; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000628:therapy*; D012895:Sleep, REM; D013997:Time Factors; D016896:Treatment Outcome