title: A facile synthesis of 1-(5'-O-acetyl-3'-O-benzyl-beta-D-xylofuranosyl)thymidine: a potentially viable intermediate for the preparation of the anti-AIDS drugs, AZT and D4T.
abstract: The title compound has been synthesized by smooth condensation of 1,2-anhydro-5-O-acetyl-3-O-benzyl-alpha-D-xylofuranose, obtained from D-xylose through a series of mild and effective reactions, with activated thymine in the absence of catalyst.
authors.affiliation: Research Center for Eco-Environmental Sciences, Academia Sinica, Beijing, PR China.
authors.forename: J
authors.initials: J
authors.lastname: Ning
authors.forename: F
authors.initials: F
authors.lastname: Kong
mesh_terms: D019380:Anti-HIV Agents / Q000138:chemical synthesis*; D018119:Stavudine / Q000138:chemical synthesis; D013936:Thymidine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*; D015215:Zidovudine / Q000138:chemical synthesis
chemical_list: C416834:1-(5'-O-acetyl-3'-benzylxylofuranosyl)thymidine; D019380:Anti-HIV Agents; D015215:Zidovudine; D018119:Stavudine; D013936:Thymidine