[Effects of hemosplenic perfusion on the state of humoral immunity in suppurative-septic complications in emergency abdominal surgery].
Hemosplenoperfusion (HSP) through the donor porcine spleen was used in complex treatment of 75 patients aged from 16 to 75 with pyo-septic complications of diseases and traumas of the abdominal cavity. The influence of HSP on the state of humoral immunity was estimated by the level of antibacterial antibodies to the antigens of E. coli, Ps. aeruginosa, Pr. mirabilis, St. aureus, Bact. fragilis, Bact. bifidum and antiendotoxin antibodies to glycolipid S. Minnesota RE 595, general cortical part of the lipopolysaccharide of Gram-negative bacteria. The use of HPS promoted the resolving of endogenous intoxication, elevation of the strain of humoral antibacterial immunity and is characterized by a reliable increase of the level of antibacterial antibodies in the dynamics of treatment.
Chikaev
V F
VF
Safina
N A
NA
Zinkevich
O D
OD
D000005:Abdomen / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology*; D000917:Antibody Formation; D004731:Endotoxins / Q000276:immunology; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000276:immunology / Q000628:therapy*; D018805:Sepsis / Q000276:immunology / Q000628:therapy*; D013154:Spleen / Q000276:immunology*; D013492:Suppuration; D013552:Swine
D000907:Antibodies, Bacterial; D004731:Endotoxins