title: Surgery of toxic goitre in non-euthyroid patients: a preliminary report.
abstract: In recent years, the cost of medical care has skyrocketed and since medical treatment is not free, some drugs are now beyond the reach of some patients. One of such drugs is the antithyroid drug, carbimazole, which has been priced beyond the reach of our thyrotoxic patients. We have therefore been forced to operate on these patients whenever they present, even while thyrotoxic. The principle of our management is to anticipate the development of thyroid crises and to prevent its occurrence post-operatively by using saturated solution of potassium iodide (SSKI) or Lugol's iodine, propranolol, diazepam, and hydrocortisone. This is a preliminary report of the first twelve consecutive patients so treated.
authors.affiliation: Department of Surgery, College of Medicine, University College Hospital, Ibadan, Nigeria.
authors.forename: O G
authors.initials: OG
authors.lastname: Ajao
authors.forename: O A
authors.initials: OA
authors.lastname: Soyannwo
authors.forename: C A
authors.initials: CA
authors.lastname: Adebamowo
authors.forename: L I
authors.initials: LI
authors.lastname: Okeke
authors.forename: J K
authors.initials: JK
authors.lastname: Ladipo
authors.forename: P T
authors.initials: PT
authors.lastname: Sotunmbi
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D013956:Antithyroid Agents / Q000191:economics; D002231:Carbimazole / Q000191:economics; D003975:Diazepam / Q000627:therapeutic use; D005252:Fees, Pharmaceutical; D005260:Female; D006042:Goiter / Q000601:surgery*; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D011193:Potassium Iodide / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use; D013964:Thyroid Neoplasms / Q000601:surgery; D013965:Thyroidectomy / Q000379:methods; D013971:Thyrotoxicosis / Q000517:prevention & control / Q000601:surgery*
chemical_list: D000889:Anti-Arrhythmia Agents; D000893:Anti-Inflammatory Agents; D013956:Antithyroid Agents; D006993:Hypnotics and Sedatives; D011193:Potassium Iodide; D002231:Carbimazole; D011433:Propranolol; D003975:Diazepam; D006854:Hydrocortisone