Circadian changes of heart rate in West syndrome.
Patterns of circadian and ultradian rhythms in the heart rate (HR) are described in a full-term baby with birth asphyxia and convulsions. A 24h HR recording was carried out at the age of 1, 15, 56, 289, and 295 days; West syndrome diagnosis was made when the patient was 3 months old. The HR showed no circadian rhythm in the follow-up, whereas it is known that the circadian rhythm appears in healthy infants at the age of 1 month and remains thereafter. This observation may be an indirect indicator of the interference of West syndrome with centers of neurological maturity.
Ardura
J
J
Department of Pediatrics University of Valladolid, Spain. ardura@ped.uva.es
Andres
J
J
Muñoz
A
A
Revilla
M
M
Aragon
P
P
D000204:Activity Cycles / Q000502:physiology; D000367:Age Factors; D002940:Circadian Rhythm / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013036:Spasms, Infantile / Q000503:physiopathology*