title: Thickness of the peripapillary retina in healthy subjects with different degrees of ametropia.
abstract: OBJECTIVE
  To evaluate the thickness of the peripapillary retina in healthy subjects with different degrees of ametropia.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  Forty-three healthy normal subjects, ages 15 to 64 years (38+/-15 years) were recruited.
  
  
  METHODS
  The method of retinal thickness mapping was applied to generate serial optical section images in the temporal peripapillary retinal area. The digitized images were analyzed to detect the separation between the vitreoretinal and chorioretinal interfaces. The separation was converted to absolute thickness by taking into account the magnification of the optical system and the optical dimensions of the eyes.
  
  
  METHODS
  The refractive error of the eyes ranged from +8.25 to -12.75 diopters (spherical equivalent). The axial length of the eyes ranged from 19.3 to 27.35 mm. The retinal thickness in a 2- x 2-mm temporal peripapillary retinal area was determined.
  
  
  RESULTS
  The separation between the retinal interfaces decreased with increasing axial length (P<0.001). The thickness in the temporal peripapillary retinal area was not significantly correlated with the axial length of the eye (P = 0.3). A lack of statistically significant difference between the average thickness in the hyperopic, emmetropic, and myopic eyes (P> or =0.06) was found.
  
  
  CONCLUSIONS
  The average thickness in the temporal peripapillary retinal area was not influenced by the axial length of the eye, when the magnification of the optical system and the optical dimension of the eyes were taken into consideration.
authors.affiliation: Applied Physics Laboratory, Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA.
authors.forename: E
authors.initials: E
authors.lastname: Garcia-Valenzuela
authors.forename: M
authors.initials: M
authors.lastname: Mori
authors.forename: D P
authors.initials: DP
authors.lastname: Edward
authors.forename: M
authors.initials: M
authors.lastname: Shahidi
mesh_terms: D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D003430:Cross-Sectional Studies; D003941:Diagnostic Techniques, Ophthalmological; D005123:Eye / Q000033:anatomy & histology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology*; D012030:Refractive Errors / Q000473:pathology*; D012160:Retina / Q000473:pathology*