title: [The spectrum of cytotoxic lymphomas of the skin].
abstract: Cytotoxic lymphomas are peripheral T- and natural killer-cell lymphomas with primary or secondary skin manifestations. They constitute a heterogeneous group of lymphoproliferative disease. They are characterized by expression of cytotoxic proteins and are frequently associated with an aggressive clinical course. A brief introduction to cytotoxic lymphocytes and proteins is followed by a detailed description of clinical, histological, immunohistochemical and genetic characteristics of cutaneous cytotoxic lymphomas.
authors.affiliation: Universitätsklinik für Dermatologie und Venerologie Graz.
authors.forename: L
authors.initials: L
authors.lastname: el Shabrawi-Caelen
authors.forename: L
authors.initials: L
authors.lastname: Cerroni
authors.forename: W
authors.initials: W
authors.lastname: Sterry
authors.forename: H
authors.initials: H
authors.lastname: Audring
authors.forename: H
authors.initials: H
authors.lastname: Kerl
mesh_terms: D006801:Humans; D016130:Immunophenotyping; D007694:Killer Cells, Natural / Q000276:immunology*; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis* / Q000276:immunology; D016411:Lymphoma, T-Cell, Peripheral / Q000175:diagnosis* / Q000276:immunology; D012878:Skin Neoplasms / Q000175:diagnosis / Q000276:immunology*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*