title: Otitis media as a sign of Wegener's granulomatosis in childhood.
abstract: Wegener's granulomatosis (WG) is a rare disease among paediatric patients. Chronic otitis media with or without facial nerve dysfunction is a known manifestation of the disease among adults. A case of a 15-year-old boy with WG, whose initial symptoms were acute otitis media and facial nerve paralysis, is presented. The otorhinolaryngological manifestations, as well as diagnostic and current treatment modalities in paediatric patients with WG, are discussed.
authors.affiliation: Department of Otorhinolaryngology, Helsinki University Central Hospital, Finland. timo.atula@hus.fi
authors.forename: T
authors.initials: T
authors.lastname: Atula
authors.forename: V
authors.initials: V
authors.lastname: Honkanen
authors.forename: J
authors.initials: J
authors.lastname: Tarkkanen
authors.forename: J
authors.initials: J
authors.lastname: Jero
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D002908:Chronic Disease; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D004432:Ear, Middle / Q000000981:diagnostic imaging; D005154:Facial Nerve / Q000503:physiopathology; D005158:Facial Paralysis / Q000209:etiology / Q000503:physiopathology; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D010033:Otitis Media / Q000175:diagnosis* / Q000209:etiology*; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000008:administration & dosage / Q000627:therapeutic use; D014420:Turbinates / Q000473:pathology
chemical_list: D000892:Anti-Infective Agents, Urinary; D000893:Anti-Inflammatory Agents; D018906:Antineoplastic Agents, Alkylating; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D003520:Cyclophosphamide; D011241:Prednisone