Specificity of radioprotective and cytotoxic effects of cysteamine in HeLa S3 cells: generation of peroxide as the mechanism of paradoxical toxicity.
Takagi
Y
Y
Shikita
M
M
Terasima
T
T
Akaboshi
S
S
D002374:Catalase / Q000494:pharmacology; D003543:Cysteamine / Q000494:pharmacology* / Q000633:toxicity; D019856:Ethanolamine / Q000494:pharmacology; D005021:Ethylamines / Q000494:pharmacology; D006146:Guanidines / Q000494:pharmacology; D006367:HeLa Cells / Q000187:drug effects* / Q000528:radiation effects; D006735:Horseradish Peroxidase / Q000494:pharmacology; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism; D011837:Radiation-Protective Agents / Q000494:pharmacology* / Q000633:toxicity; D013438:Sulfhydryl Compounds / Q000494:pharmacology; D013482:Superoxide Dismutase / Q000494:pharmacology
D005021:Ethylamines; D006146:Guanidines; D011837:Radiation-Protective Agents; D013438:Sulfhydryl Compounds; D019856:Ethanolamine; D003543:Cysteamine; D006861:Hydrogen Peroxide; D006735:Horseradish Peroxidase; D002374:Catalase; D013482:Superoxide Dismutase; C007638:ethanethiol; C100078:2-mercaptoethylguanidine; C041564:ethylamine