title: Endoscopic injection sclerotherapy control of intractable hematuria following radiation-induced hemorrhagic cystitis. A novel approach.
abstract: OBJECTIVE
  To establish the utility of endoscopic sclerotherapy using 1% ethoxysclerol for the control of intractable hematuria following post-irradiation telangiectatic cystitis (PTC).
  
  
  METHODS
  Our experience of treating 4 patients (one female and three male) with massive exsanguinating hematuria resulting from PTC, using a combined intralesional and perilesional injection of 1% ethoxysclerol, is presented. Observation on the distribution, grading of telangiectasis and pattern of bleeding are made.
  
  
  RESULTS
  A dramatic and lasting cessation of the hematuria in all the 4 patients was achieved during the follow-up period varying from 1 month to 4 years.
  
  
  CONCLUSIONS
  Endoscopic injection sclerotherapy is a simple, highly effective, less invasive new technique in the management of massive and intractable hematuria due to radiation-induced telangiectasia of the urinary bladder.
authors.affiliation: Department of Urology and Renal Transplantation, Sanjay Ghandi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India. siva@sgpgi.ac.in
authors.forename: H S
authors.initials: HS
authors.lastname: Tunuguntla
authors.forename: M
authors.initials: M
authors.lastname: Bhandari
authors.forename: A
authors.initials: A
authors.lastname: Srivastava
authors.forename: R
authors.initials: R
authors.lastname: Kapoor
authors.forename: T K
authors.initials: TK
authors.lastname: Saha
mesh_terms: D000328:Adult; D003556:Cystitis / Q000209:etiology*; D005260:Female; D006417:Hematuria / Q000188:drug therapy* / Q000209:etiology*; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D000077423:Polidocanol; D011092:Polyethylene Glycols / Q000008:administration & dosage*; D011878:Radiotherapy / Q000009:adverse effects*; D012597:Sclerosing Solutions / Q000008:administration & dosage*; D015911:Sclerotherapy
chemical_list: D012597:Sclerosing Solutions; D000077423:Polidocanol; D011092:Polyethylene Glycols