[The postradiation use of vitamin-containing complexes and a phycocyanin extract in a radiation lesion in rats].
Wistar rats have been exposed to X-rays with a dose of 5 Gy. Significant decrease in dehydrogenase activity, energy-rich phosphate level and efficiency of antioxidant defence and significant increase in pyruvate amount were observed within 4 weeks. It was also found that the feeding of exposed rats with phycocyanin extract from blue-green algae Spirulina platensis lead to correcting effect. The same result was observed after injections of tocopherol or complex of six water-soluble vitamins. The combination of above mentioned compounds had more marked effect, especially at the presence unitiole and Na2Se.
Karpov
L M
LM
Mechnikov Odessa State University, Ukraina.
Brown
I I
II
Poltavtseva
N V
NV
Ershova
O N
ON
Karakis
S G
SG
Vasil'eva
T V
TV
Chaban
Iu L
IuL
D000818:Animals; D000458:Cyanobacteria; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D010798:Phycocyanin / Q000627:therapeutic use*; D011833:Radiation Injuries, Experimental / Q000188:drug therapy* / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014810:Vitamin E / Q000627:therapeutic use; D014815:Vitamins / Q000627:therapeutic use*
D014815:Vitamins; D010798:Phycocyanin; D014810:Vitamin E