A merger of rational drug design and combinatorial chemistry: development and application of peptide secondary structure mimetics.
Recent efforts toward the development of peptide secondary structure mimetics at Molecumetics Ltd. for the discoveries of new drug candidates utilizing combinatorial chemistry with solid phase synthesis are described.
Kim
H O
HO
Molecumetics Ltd., Bellevue, WA 98005-2199, USA.
Kahn
M
M
D020650:Combinatorial Chemistry Techniques; D015195:Drug Design; D018716:Molecular Mimicry; D010455:Peptides / Q000737:chemistry*; D017433:Protein Structure, Secondary
D010455:Peptides