MouseNet database: digital management of a large-scale mutagenesis project.
The Munich ENU Mouse Mutagenesis Screen is a large-scale mutant production, phenotyping, and mapping project. It encompasses two animal breeding facilities and a number of screening groups located in the general area of Munich. A central database is required to manage and process the immense amount of data generated by the mutagenesis project. This database, which we named MouseNet(c), runs on a Sybase platform and will finally store and process all data from the entire project. In addition, the system comprises a portfolio of functions needed to support the workflow management of the core facility and the screening groups. MouseNet(c) will make all of the data available to the participating screening groups, and later to the international scientific community. MouseNet(c) will consist of three major software components:* Animal Management System (AMS)* Sample Tracking System (STS)* Result Documentation System (RDS)MouseNet(c) provides the following major advantages:* being accessible from different client platforms via the Internet* being a full-featured multi-user system (including access restriction and data locking mechanisms)* relying on a professional RDBMS (relational database management system) which runs on a UNIX server platform* supplying workflow functions and a variety of plausibility checks.
Pargent
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Institute of Experimental Genetics, GSF Research Center for Environment and Health, 85764 Neuherberg, Germany.
Heffner
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Schäble
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KF
Soewarto
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Fuchs
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Hrabé de Angelis
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D000818:Animals; D003201:Computers; D003628:Database Management Systems; D016208:Databases, Factual; D020407:Internet; D051379:Mice / Q000235:genetics*; D016296:Mutagenesis