Isolation of luteolin 7-O-rutinoside and esculetin with potential antioxidant activity from the aerial parts of Artemisia montana.
The antioxidant activity of Artemisia montana was determined by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and inhibitory activity against free radical generation of hepatocytes (AC2F). The methanol extract of A. montana showed strong radical scavenging activity at a concentration of 10.1 microg/ml, and thus fractionated by solvent extraction. Esculetin and luteolin 7-O-rutinoside (scolymoside) were isolated as the active principles from the EtOAc and Interphase fractions, respectively. The antioxidant activity of these compounds were comparable to that of L-ascorbic acid.
Kim
N M
NM
Faculty of Food Science and Biotechnology, Pukyong National University, Pusan, Korea.
Kim
J
J
Chung
H Y
HY
Choi
J S
JS
D000975:Antioxidants / Q000302:isolation & purification*; D019306:Artemisia / Q000737:chemistry*; D005419:Flavonoids; D006569:Hesperidin / Q000031:analogs & derivatives* / Q000302:isolation & purification; D047311:Luteolin; D010946:Plants, Medicinal; D014468:Umbelliferones / Q000302:isolation & purification*
D000975:Antioxidants; D005419:Flavonoids; D014468:Umbelliferones; C009652:veronicastroside; D006569:Hesperidin; D047311:Luteolin; C007628:esculetin