Dedifferentiated liposarcoma with chondroblastic osteosarcomatous dedifferentiation.
We describe a rare case of dedifferentiated liposarcoma with features resembling chondroblastic osteosarcoma in the dedifferentiated component. The tumor was removed from the left thigh in a 78-year-old male. It consisted of a well-differentiated liposarcoma and an anaplastic component that contained numerous osteoid and cartilaginous tissues surrounded by high-grade spindle cell sarcoma. To our knowledge, only two cases similar to the divergent chondroblastic osteosarcomatous dedifferentiation of this disease have been reported in the literature.
Yamamoto
T
T
Department of Orthopaedic Surgery, Kobe University School of Medicine, Kobe, Japan. yamatetu@med.kobe-u.ac.jp
Matsushita
T
T
Marui
T
T
Mizuno
K
K
Minami
R
R
Hayashi
Y
Y
Hanioka
K
K
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001859:Bone Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D002454:Cell Differentiation; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008080:Liposarcoma / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D008175:Lung Neoplasms / Q000556:secondary / Q000601:surgery; D008297:Male; D009363:Neoplasm Proteins / Q000032:analysis; D012516:Osteosarcoma / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D011879:Radiotherapy Dosage; D014057:Tomography, X-Ray Computed
D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins