title: A urethral stent for the treatment of detrusor-striated sphincter dyssynergia.
abstract: OBJECTIVE
  To assess the technique, efficacy and complications of the Ultraflex urethral stent (Boston Scientific Corp., Boston, MA) for the treatment of detrusor-striated sphincter dyssynergia (DSD).
  
  
  METHODS
  Forty consecutive patients with DSD who had a Ultraflex stent placed in the membranous urethra were evaluated prospectively. DSD was caused by spinal cord injury in 30, multiple sclerosis in six and other neurological diseases in four. All patients were either tetraplegic or paraplegic and unable to use intermittent self-catheterization. Previous bladder management consisted of an indwelling catheter in 15 patients, chronic suprapubic catheters in two, intermittent catheterization in nine, and trigger reflex micturition in 14. The Ultraflex stent was placed under local anaesthesia. The stents were 50 mm long in 36 patients, 45 mm in two and 40 mm in two. The mean (SD) follow-up was 16.9 (13. 8) months.
  
  
  RESULTS
  The mean (SD) residual urine decreased from 245. 9 (117) mL before stenting to 65.2 (19.3) mL at 12 months afterward (n = 19). One stent was removed at 13 months for chronic prostatic and urinary tract infection leading to autonomic dysreflexia. There was no stent stenosis and 17 of 18 stents had > 75% epithelial coverage at one year. None of the stents migrated. Seven patients underwent secondary bladder neck incision through the stent. The stent length was increased in four patients using a second overlapping distal stent, twice during the first procedure and twice within 6 months because the sphincter was inadequately covered.
  
  
  CONCLUSIONS
  The Ultraflex stent achieved the expected results for a prosthetic sphincterotomy and appears to be an appropriate but less invasive treatment for DSD.
authors.affiliation: Department of Urology, Pitié-Salpétrière Hospital, University Pierre et Marie Curie (Paris VI), Paris, France. emmanuel.chartier-kastler@psl.ap-hop-paris.fr
authors.forename: E J
authors.initials: EJ
authors.lastname: Chartier-Kastler
authors.forename: L
authors.initials: L
authors.lastname: Thomas
authors.forename: B
authors.initials: B
authors.lastname: Bussel
authors.forename: M B
authors.initials: MB
authors.lastname: Chancellor
authors.forename: F
authors.initials: F
authors.lastname: Richard
authors.forename: P
authors.initials: P
authors.lastname: Denys
mesh_terms: D000328:Adult; D000368:Aged; D001672:Biocompatible Materials; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D019919:Prosthesis Implantation; D013119:Spinal Cord Injuries / Q000150:complications*; D015607:Stents; D014521:Urethra; D001750:Urinary Bladder, Neurogenic / Q000150:complications* / Q000503:physiopathology; D014546:Urinary Catheterization / Q000379:methods; D016055:Urinary Retention / Q000503:physiopathology / Q000601:surgery*; D014563:Urodynamics
chemical_list: D001672:Biocompatible Materials