title: Synthesis and antioxidant activity of flavanoid derivatives containing a 1,4-benzodioxane moiety.
abstract: Flavanoids bearing a 1,4-benzodioxane moiety [rac-15a, -16a, -17, -18, (-)-15a, (-)-16a] were prepared from protocatechualdehyde (5) and tested for inhibitory activity on the superoxide anion (O2.-) release by human polymorphonuclear leukocytes (PMNLs).
authors.affiliation: Department of Organic Chemistry, University of Debrecen, Hungary.
authors.forename: A
authors.initials: A
authors.lastname: Czompa
authors.forename: Z
authors.initials: Z
authors.lastname: Dinya
authors.forename: S
authors.initials: S
authors.lastname: Antus
authors.forename: Z
authors.initials: Z
authors.lastname: Varga
mesh_terms: D000975:Antioxidants / Q000138:chemical synthesis* / Q000494:pharmacology; D005419:Flavonoids / Q000138:chemical synthesis* / Q000494:pharmacology; D006801:Humans; D009504:Neutrophils / Q000378:metabolism; D013329:Structure-Activity Relationship; D013481:Superoxides / Q000378:metabolism
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D013481:Superoxides