Erythropoietic protoporphyria: treatment with antioxidants and potential cure with gene therapy.
Mathews-Roth
M M
MM
Department of Medicine, Channing Laboratory, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation; D002338:Carotenoids / Q000627:therapeutic use; D002478:Cells, Cultured; D005260:Female; D005294:Ferrochelatase / Q000235:genetics* / Q000378:metabolism; D018014:Gene Transfer Techniques; D015316:Genetic Therapy; D006801:Humans; D008297:Male; D051379:Mice; D008812:Mice, Hairless; D008807:Mice, Inbred BALB C; D010100:Oxygen / Q000502:physiology; D010777:Photochemistry; D017121:Porphyria, Hepatoerythropoietic / Q000188:drug therapy / Q000628:therapy*; D026082:Singlet Oxygen; D012867:Skin / Q000187:drug effects / Q000528:radiation effects; D013472:Sunlight; D014162:Transfection; D014466:Ultraviolet Rays; D019207:beta Carotene / Q000494:pharmacology
D000975:Antioxidants; D019207:beta Carotene; D026082:Singlet Oxygen; D002338:Carotenoids; D005294:Ferrochelatase; D010100:Oxygen