title: [Use of pentoxifylline in pediatric patients with grade IV (OMS) lupus nephropathy who have received multiple treatments].
abstract: OBJECTIVE
  Systemic Lupus Eritematosus is an autoimmune disease, the incidence in pediatric poblation in about 5%, and until 90% develop nephropathy.
  
  
  METHODS
  Included patients with lupic nephropathy grade IV (OMS) ages between 0 and 16 years old, multitreated, who administrated PTX. We take samples before treatment, during, and 4 month after, evaluating renal function and hepatic function.
  
  
  RESULTS
  For female, tow male, promedium age 14.1 years old. Poteinuria get a significative p = 0.0012; hematuria was lowering its levels, While immune circulating complex, get too a significative p = 0.0050. In creatinine inverse showed an important modification of its pending.
  
  
  CONCLUSIONS
  This results demonstrates, that PTX in nephritis lupic patients, helps to brake the habitual deterioration in renal function. Includes more patients for a long time of treatment, we'll get better results than this.
authors.affiliation: Departamento de Alergia e Inmunología Clínica, Hospital General Dr. Darío Fernández F, México D.F. jambofly@yahoo.com
authors.forename: M J
authors.initials: MJ
authors.lastname: Vázquez García
authors.forename: M E
authors.initials: ME
authors.lastname: Vargas Camaño
authors.forename: R
authors.initials: R
authors.lastname: Olalde Carmona
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008180:Lupus Erythematosus, Systemic / Q000145:classification / Q000150:complications* / Q000188:drug therapy*; D008297:Male; D009393:Nephritis / Q000188:drug therapy* / Q000209:etiology*; D010431:Pentoxifylline / Q000627:therapeutic use*
chemical_list: D010431:Pentoxifylline