The classification of personality disorders should be rooted in biology.
As scientific classifications develop over time, they become based less on observations and more on mechanisms. Existing dimensional schema are limited by being overly broad and by being rooted in self-report rather than theory. Future models should be consistent with a scientific hierarchy, leading to a bottom-up classification of traits and disorders, linking molecular genetics, neurobiological markers, and temperamental variations.
Paris
J
J
Department of Psychiatry, McGill University, Montréal, Québec, Canada. cxjp@musica.mcgill.ca
D020022:Genetic Predisposition to Disease; D006801:Humans; D010554:Personality Disorders / Q000145:classification* / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology; D011569:Psychiatric Status Rating Scales; D011603:Psychophysiology; D012307:Risk Factors