An unusual case of cutaneous vasculitis.
BACKGROUND
We report an unusual case of a patient with clinical and histological features of cutaneous vasculitis. CASE PICTURE: A middle-aged Chinese male presented with livedo reticularis and digital gangrene without visceral involvement. Skin biopsy showed features suggestive of cutaneous vasculitis. Repeated testing for anticardiolipin antibody was negative.


METHODS
He was treated with two courses of intravenous prostacyclin and pulsed with one course of intravenous methylprednisolone. He was also put on oral prednisolone, pentoxifylline, aspirin, nifedipine and colchicine in addition to symptomatic therapy.


RESULTS
There was gradual improvement of his toe discolouration and relief of pain.


CONCLUSIONS
This is an interesting case of cutaneous vasculitis, which has features of polyarteritis nodosa and the antiphospholipid syndrome, who responded well to intravenous prostacyclin, steroids, pentoxifylline, aspirin, nifedipine and colchicine.
Goon
A T
AT
National Skin Centre, Singapore.
Tay
Y K
YK
Giam
Y C
YC
Lau
T C
TC
Chan
H L
HL
D001707:Biopsy, Needle; D005500:Follow-Up Studies; D005734:Gangrene / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017445:Skin Diseases, Vascular / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D014034:Toes; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy