Vasopressin and bradykinin receptors in the kidney: implications for tubular function.
Vasopressin and bradykinin are two of the most important peptides in regulating vascular tone, water, and ionic balance in the body, and thus they play a key role in controlling blood pressure. In addition to being a potent vasoconstrictor, Vasopressin also has an antidiuretic activity in the kidney, whereas kinins regulate renal blood flow in addition to their vasodilatory and natriuretic activity. We review here the primary evidence for the localization of the vasopressin and kinin receptors and their role in ionic and water regulation in the kidney.
Gonzalez
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Institute of Physiology, Universidad Austral de Chile. cbgonzal@uach.cl
Figueroa
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D000818:Animals; D001127:Arginine Vasopressin / Q000502:physiology*; D006801:Humans; D016234:Kallikrein-Kinin System / Q000502:physiology; D007684:Kidney Tubules / Q000378:metabolism*; D007705:Kinins / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D018002:Receptors, Bradykinin / Q000502:physiology*; D017483:Receptors, Vasopressin / Q000502:physiology*; D012964:Sodium / Q000378:metabolism
D007705:Kinins; D018002:Receptors, Bradykinin; D017483:Receptors, Vasopressin; D001127:Arginine Vasopressin; D012964:Sodium; D011188:Potassium