title: Detection of thrombosis in the portal venous system: comparison of contrast-enhanced MR angiography with intraarterial digital subtraction angiography.
abstract: OBJECTIVE
  To determine whether intraarterial digital subtraction angiography (DSA) can be replaced by contrast material-enhanced magnetic resonance (MR) angiography in the assessment of patency or thrombosis of the portal venous system in patients with portal hypertension.
  
  
  METHODS
  Thirty-six patients with portal hypertension underwent contrast-enhanced MR angiography and intraarterial DSA for assessment of the portal venous system. The images were evaluated for vessel patency or thrombosis of the portal, splenic, or superior mesenteric vein.
  
  
  RESULTS
  Of the 101 vessels evaluated, 42 were thrombosed. Overall sensitivity, specificity, and accuracy for the detection of thrombosis were 100%, 98%, and 99%, respectively, for MR angiography and 91%, 100%, and 96%, respectively, for DSA; differences between the imaging methods were not statistically significant. Only in four patients with six vessels (6%) were there discordant findings between MR angiography and DSA.
  
  
  CONCLUSIONS
  Noninvasive contrast-enhanced MR angiography has the potential to replace intraarterial DSA as the standard method to assess the whole portal venous system.
authors.affiliation: Department of Radiology, University of Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany. kreft@mailer.meb.uni-bonn.de
authors.forename: B
authors.initials: B
authors.lastname: Kreft
authors.forename: H
authors.initials: H
authors.lastname: Strunk
authors.forename: S
authors.initials: S
authors.lastname: Flacke
authors.forename: M
authors.initials: M
authors.lastname: Wolff
authors.forename: R
authors.initials: R
authors.lastname: Conrad
authors.forename: J
authors.initials: J
authors.lastname: Gieseke
authors.forename: D
authors.initials: D
authors.lastname: Pauleit
authors.forename: R
authors.initials: R
authors.lastname: Bachmann
authors.forename: A
authors.initials: A
authors.lastname: Hirner
authors.forename: H H
authors.initials: HH
authors.lastname: Schild
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015901:Angiography, Digital Subtraction; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology; D018810:Magnetic Resonance Angiography; D008297:Male; D008641:Mesenteric Vascular Occlusion / Q000175:diagnosis / Q000000981:diagnostic imaging; D008642:Mesenteric Veins / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D011169:Portal Vein / Q000000981:diagnostic imaging / Q000473:pathology; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013162:Splenic Vein / Q000000981:diagnostic imaging / Q000473:pathology; D020246:Venous Thrombosis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA