Commitment factors for T helper cells.
Cytokines are dominant factors in driving the development of T helper cell subsets via specific signaling pathways. Transcription factors specific to the T helper cell lineages have also been shown to determine the commitment of Th1 and Th2 cells to the production of distinct profiles of cytokines.
O'Garra
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Division of Immunology, DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, CA 94304-1104, USA.
D000818:Animals; D002454:Cell Differentiation; D016207:Cytokines / Q000502:physiology; D006801:Humans; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology*; D018417:Th1 Cells / Q000166:cytology / Q000276:immunology; D018418:Th2 Cells / Q000166:cytology / Q000276:immunology
D016207:Cytokines