title: Cytotoxic neolignans from the stem wood of Machilus obovatifolia.
abstract: Four new cytotoxic neolignans, machilusol A (1), machilusol C (3), machilusol D (4), machilusol E (5) as well as two new inactive neolignans, machilusol B (2) and machilusol F (6), were isolated from the stem wood of Machilus obovatifolia. All structures were identified by means of spectroscopic analysis.
authors.affiliation: Graduate Institute of Natural Products, Kaohsiung Medical University, Taiwan, R.O.C. ialits@cc.kmu.edu.tw
authors.forename: I L
authors.initials: IL
authors.lastname: Tsai
authors.forename: J H
authors.initials: JH
authors.lastname: Chen
authors.forename: C Y
authors.initials: CY
authors.lastname: Duh
authors.forename: I S
authors.initials: IS
authors.lastname: Chen
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016227:Benzoquinones; D003124:Colorimetry; D019073:HT29 Cells; D006801:Humans; D007097:Imines; D007202:Indicators and Reagents; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051379:Mice; D010936:Plant Extracts / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry; D014197:Trees / Q000737:chemistry*; D014407:Tumor Cells, Cultured; D014934:Wood
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D016227:Benzoquinones; D007097:Imines; D007202:Indicators and Reagents; D017705:Lignans; D010936:Plant Extracts; C010358:N,2,6-trichloro-4-benzoquinone imine