[Enzyme clearance in intermittent hemofiltration in patients with acute renal failure].
OBJECTIVE
To characterize elimination of some enzymes in intermittent hemofiltration (HF) in patients with acute renal failure (ARF).


METHODS
22 patients with oliguric ARF have undergone 52 procedures of intermittent HF. Before the procedure and after it the activity of enzymes (AA, AP, ACE, LAP, GGT, GDG, AlAT, AsAT, CPG, LDG) was measured in the samples of plasma and filtrate.


RESULTS
Besides ACE and AlAT, all the enzymes concentrations were elevated in all the patients. HF did not change significantly the enzymes activity. Most of the enzymes were eliminated from the blood. In some samples the enzymes activity was low or absent.


CONCLUSIONS
Further studies are necessary to answer questions aroused by the findings.
Timokhov
V S
VS
Kazakov
I V
IV
Selezneva
S N
SN
Komissarova
I V
IV
Smirnova
L M
LM
D058186:Acute Kidney Injury / Q000201:enzymology* / Q000628:therapy; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000032:analysis / Q000097:blood; D015314:Dialysis Solutions / Q000737:chemistry*; D018450:Disease Progression; D004798:Enzymes / Q000032:analysis / Q000097:blood*; D005260:Female; D006440:Hemofiltration / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
D015415:Biomarkers; D015314:Dialysis Solutions; D004798:Enzymes