Sarcoidosis presenting with large vessel vasculitis and osteosclerosis-related bone and joint pain.
A 34-year-old African-American female diagnosed earlier with idiopathic thrombocytopenic purpura (ITP), lymphadenopathy, splenomegaly, uveitis, and pulmonary nodules, developed a subclavian artery aneurysm, and generalized annular osteosclerotic lesions with disabling arthralgias. Biopsies from bone and lymph node revealed non-caseating granulomas and no evidence of malignancy or infection, confirming the clinical impression of sarcoidosis.
Kirou
K A
KA
Division of Rheumatology, Hospital for Special Surger, New York, NY 10021, USA. kirouk@hss.edu
Bateman
H E
HE
Bansal
M
M
Schneider
R
R
Fantini
G A
GA
Paget
S A
SA
D000328:Adult; D018771:Arthralgia / Q000473:pathology*; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D010026:Osteosclerosis / Q000473:pathology*; D012507:Sarcoidosis / Q000473:pathology*; D013921:Thrombocytopenia / Q000175:diagnosis; D014657:Vasculitis / Q000473:pathology*