title: Three cases of pityriasis rubra pilaris successfully treated with cyclosporin A.
abstract: BACKGROUND
  Pityriasis rubra pilaris (PRP) is reported to respond poorly to cyclosporin A (CsA).
  
  
  OBJECTIVE
  We attempted to determine the efficacy of CsA in the treatment of classic adult-type PRP.
  
  
  METHODS
  Three patients with classic adult-type PRP were treated with 5 mg/kg/day CsA.
  
  
  RESULTS
  A sustained clinical response was achieved within 2-4 weeks of therapy. Relapses were noted when the CsA dose was decreased to 1.2 mg/kg/day.
  
  
  CONCLUSIONS
  CsA should be considered in the treatment of classical adult-type PRP.
authors.affiliation: Department of Dermatology, Kagoshima University Faculty of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Usuki
authors.forename: M
authors.initials: M
authors.lastname: Sekiyama
authors.forename: T
authors.initials: T
authors.lastname: Shimada
authors.forename: S
authors.initials: S
authors.lastname: Shimada
authors.forename: T
authors.initials: T
authors.lastname: Kanzaki
mesh_terms: D000328:Adult; D000368:Aged; D016572:Cyclosporine / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010916:Pityriasis Rubra Pilaris / Q000188:drug therapy* / Q000473:pathology; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D003879:Dermatologic Agents; D016572:Cyclosporine