title: Urinary tract infection in full-term newborn infants: risk factor analysis.
abstract: OBJECTIVE
  To analyze the correlation of risk factors to the occurrence of urinary tract infection in full-term newborn infants.
  
  
  METHODS
  Retrospective study (1997) including full-term infants having a positive urine culture by bag specimen. Urine collection was based on: fever, weight loss > 10% of birth weight, nonspecific symptoms (feeding intolerance, failure to thrive, hypoactivity, debilitate suction, irritability), or renal and urinary tract malformations. In these cases, another urine culture by suprapubic bladder aspiration was collected to confirm the diagnosis. To compare and validate the risk factors in each group, the selected cases were divided into two groups: Group I - positive urine culture by bag specimen collection and negative urine culture by suprapubic aspiration, and Group II - positive urine culture by bag specimen collection and positive urine culture by suprapubic aspiration.
  
  
  RESULTS
  Sixty one infants were studied, Group I, n = 42 (68.9%) and Group II, n = 19 (31.1%). The selected risk factors (associated infectious diseases, use of broad-spectrum antibiotics, renal and urinary tract malformations, mechanical ventilation, parenteral nutrition and intravascular catheter) were more frequent in Group II (p<0.05). Through relative risk analysis, risk factors were, in decreasing importance: parenteral nutrition, intravascular catheter, associated infectious diseases, use of broad-spectrum antibiotics, mechanical ventilation, and renal and urinary tract malformations.
  
  
  CONCLUSIONS
  The results showed that parenteral nutrition, intravascular catheter, and associated infectious diseases contributed to increase the frequency of neonatal urinary tract infection, and in the presence of more than one risk factor, the occurrence of urinary tract infection rose up to 11 times.
authors.affiliation: Department of Pediatrics, Hospital das Clínicas, Faculty of Medicine, University of São Paulo, Brazil.
authors.forename: M C
authors.initials: MC
authors.lastname: Falcão
authors.forename: C R
authors.initials: CR
authors.lastname: Leone
authors.forename: R A
authors.initials: RA
authors.lastname: D'Andrea
authors.forename: R
authors.initials: R
authors.lastname: Berardi
authors.forename: N A
authors.initials: NA
authors.lastname: Ono
authors.forename: F A
authors.initials: FA
authors.lastname: Vaz
mesh_terms: D002404:Catheterization / Q000009:adverse effects; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010288:Parenteral Nutrition / Q000009:adverse effects; D011864:Radioimmunosorbent Test; D012189:Retrospective Studies; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000209:etiology*