title: [Discitis in brucellosis is not responsive to anti-brucella treatment].
abstract: A 14-year-old girl with fever and low back pain was diagnosed as having brucellosis and diskitis. Treatment with doxycycline and gentamicin had no effect nor was there any improvement when the treatment was changed to doxycycline and rifampicin. With cessation of this treatment and administration of cloxacillin fever was reduced and the back pain disappeared. After 12 days of i.v. cloxacillin, she was released from hospital with instructions to continue cloxacillin orally for another 4 weeks. We conclude that when a patient is suffering from brucellosis and diskitis and does not respond to the usual anti-brucellosis treatment, an anti-staphylococcal preparation should be added.
authors.affiliation: Dept. of Pediatrics and Orthopedics A, Hillel Yaffe Medical Center, Hadera.
authors.forename: D
authors.initials: D
authors.lastname: Heldenberg
authors.forename: R
authors.initials: R
authors.lastname: Sevi
mesh_terms: D000293:Adolescent; D002006:Brucellosis / Q000150:complications* / Q000188:drug therapy*; D003023:Cloxacillin / Q000627:therapeutic use*; D015299:Discitis / Q000188:drug therapy / Q000382:microbiology*; D004318:Doxycycline / Q000627:therapeutic use*; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use*; D006801:Humans; D017116:Low Back Pain; D010406:Penicillins / Q000627:therapeutic use
chemical_list: D005839:Gentamicins; D010406:Penicillins; D004318:Doxycycline; D003023:Cloxacillin