[Malignant glial tumor with skeletal muscle differentiation. Description of a case].
A case of CNS gliomyosarcoma, in a 71-year-old female with skeletal muscle differentiation is presented. The tumor was composed by two cell types: one showed features typical of glial cells, the other was constituted by elements having immunohistochemical positivity with desmin, sarcomeric actin, myoglobin and myogenin antisera. It is postulated an origin from a cell capable of dual differentiation.
Marucci
G
G
Dipartimento di Oncologia, M. Malpighi, Università di Bologna, Ospedale Bellaria.
Hadjmohammadi
N
N
Cenni
P
P
Ragazzini
T
T
Eusebi
V
V
D000199:Actins / Q000032:analysis; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D002454:Cell Differentiation; D003893:Desmin / Q000032:analysis; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D018316:Gliosarcoma / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D009124:Muscle Proteins / Q000032:analysis; D018008:Myogenin / Q000032:analysis; D009211:Myoglobin / Q000032:analysis; D009217:Myosarcoma / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D009363:Neoplasm Proteins / Q000032:analysis; D009419:Nerve Tissue Proteins / Q000032:analysis; D010296:Parietal Lobe / Q000473:pathology*; D013702:Temporal Lobe / Q000473:pathology*
D000199:Actins; D014408:Biomarkers, Tumor; D003893:Desmin; C503799:MYOG protein, human; D009124:Muscle Proteins; D018008:Myogenin; D009211:Myoglobin; D009363:Neoplasm Proteins; D009419:Nerve Tissue Proteins