title: Improvement in right ventricular systolic function after surgical correction of isolated tricuspid regurgitation.
abstract: Chronic tricuspid regurgitation (TR) may lead to impairment in right ventricular (RV) function. Whether surgical correction results in restoration of normal RV geometry and function is unknown. The purpose of this study was to determine whether surgical correction of TR results in improved RV geometry and function. Measurements of RV areas were made from digitized 4-chamber echocardiographic views. Right ventricular end-diastolic volume (RVEDV), right ventricular end-systolic volume (RVESV), and ejection fraction (EF) were calculated with the single-plane subtraction method. There was a significant decrease in RVEDV (109.06 +/- 12.45 versus 71.63 +/- 6. 83; P =.005) and RVESV (76.2 +/- 9.83 versus 44.5 +/- 5.58; P =.002) and a significant increase in RVEF (0.30 +/- 0.05 versus 0.38 +/- 0. 05; P =.01) at a mean follow-up of 130 +/- 63 days after surgery. These results demonstrate significant remodeling of the right ventricle with reduction in size and improved EF after tricuspid valve surgery.
authors.affiliation: Cardiovascular Imaging Center, Department of Cardiology, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
authors.forename: D
authors.initials: D
authors.lastname: Mukherjee
authors.forename: S
authors.initials: S
authors.lastname: Nader
authors.forename: A
authors.initials: A
authors.lastname: Olano
authors.forename: M J
authors.initials: MJ
authors.lastname: Garcia
authors.forename: B P
authors.initials: BP
authors.lastname: Griffin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004452:Echocardiography; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011379:Prognosis; D020127:Recovery of Function / Q000502:physiology*; D012189:Retrospective Studies; D013318:Stroke Volume; D013599:Systole; D014262:Tricuspid Valve Insufficiency / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D016278:Ventricular Function, Right / Q000502:physiology*; D020257:Ventricular Remodeling / Q000502:physiology*