Genetic structure of Native Andean populations from Argentina inhabiting different altitudes.
On the basis of erythrocyte and serum protein polymorphisms, we investigated the level of genetic differentiation among 3 Argentinian native populations sharing ethnic and morphological characteristics but inhabiting different altitudes in the Andes. Of the 15 loci studied, 8 are monomorphic. Phenotype distribution of the polymorphic systems are in agreement with Hardy-Weinberg equilibrium, except for malic enzyme (MOD), where a silent allele was found. The 2 highland populations exhibit a close genetic similarity, probably as a result of intense gene flow. The lowland population shows reduced genetic diversity, which suggests the influence of stochastic phenomena such as the founder effect.
Demarchi
D A
DA
Cátedra de Antropología, Facultad de Ciencias Exactas, Físicas y Naturales, Universidad Nacional de Córdoba, Argentina.
Clariá
D M
DM
Dipierri
J E
JE
Gardenal
C N
CN
D000483:Alleles; D000531:Altitude; D001118:Argentina; D016009:Chi-Square Distribution; D005260:Female; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D007199:Indians, South American / Q000235:genetics*; D008297:Male; D018598:Minisatellite Repeats / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*; D012494:Sampling Studies; D044465:White People / Q000235:genetics*