title: Treatment of DYT1-generalised dystonia by stimulation of the internal globus pallidus.
abstract: In seven selected patients with dystonia musculorum deformans-1 generalised dystonia (DYT1), continuous bilateral stimulation of the globus pallidus internus was associated with substantial improvement of dystonia and functional disability.
authors.forename: P
authors.initials: P
authors.lastname: Coubes
authors.forename: A
authors.initials: A
authors.lastname: Roubertie
authors.forename: N
authors.initials: N
authors.lastname: Vayssiere
authors.forename: S
authors.initials: S
authors.lastname: Hemm
authors.forename: B
authors.initials: B
authors.lastname: Echenne
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002352:Carrier Proteins / Q000235:genetics; D002648:Child; D004422:Dystonia Musculorum Deformans / Q000235:genetics / Q000503:physiopathology / Q000628:therapy*; D011211:Electric Power Supplies; D004599:Electric Stimulation Therapy / Q000295:instrumentation / Q000379:methods*; D004567:Electrodes, Implanted; D005500:Follow-Up Studies; D005917:Globus Pallidus / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D018832:Molecular Chaperones; D009154:Mutation / Q000235:genetics; D020127:Recovery of Function; D013238:Stereotaxic Techniques; D016138:Walking / Q000502:physiology
chemical_list: D002352:Carrier Proteins; D018832:Molecular Chaperones; C108175:TOR1A protein, human