Synthesis and antispasmodic activity of analogues of natural pterosins.
The synthesis of an extensive range of analogues of natural pterosins using modified Heck coupling is reported. The smooth muscle relaxant activity of these compounds has been examimed. Several compounds with significant smooth muscle relaxant activity have been identified.
Sheridan
H
Department of Pharmacognosy, School of Pharmacy, Trinity College 2, Dublin, Ireland
Frankish
N
Farrell
R