title: [Economic aspects of using electron beam computerized tomography].
abstract: Electron beam computed tomography (EBCT) allows visualization and quantification of calcium in the coronary arteries. This has been demonstrated to correlate well with the overall plaque burden in the coronary arteries. EBCT is, therefore, well suited for the detection of early stages of coronary atherosclerosis. Especially in asymptomatic patients with several risk factors, staging coronary artery disease by coronary calcium, scanning may allow prognostic assessment and guide preventive and therapeutic interventions. To date, only scant data are available regarding the cost effectiveness and the economic impact of this imaging technique. In this manuscript we compare various methods for the diagnosis of coronary artery disease using a theoretical model and review the results of a prospective trial in our emergency room of coronary calcium scanning in patients with acute chest pain. Using Framingham data and prognostic data from long-term follow-up, we discuss the impact of coronary calcification scanning on primary preventive measures and its economical consequences. EBCT is a promising technique which has created a lot of attention due to its ease of application. It is currently undergoing critical appraisal in the medical literature. Further randomized prospective trials are needed (and underway, i.e., MESA, EDIC, CARDIA II) to better define its value and limitations in the clinical arena.
authors.affiliation: Division of Cardiology, Mayo Clinic, Rochester, MN 55902, USA.
authors.forename: T R
authors.initials: TR
authors.lastname: Behrenbeck
authors.forename: T C
authors.initials: TC
authors.lastname: Gerber
authors.forename: S
authors.initials: S
authors.lastname: Möhlenkamp
authors.forename: D A
authors.initials: DA
authors.lastname: Laudon
authors.forename: B
authors.initials: B
authors.lastname: Kantor
authors.forename: P F
authors.initials: PF
authors.lastname: Sheedy
authors.forename: J A
authors.initials: JA
authors.lastname: Rumberger
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000191:economics; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000191:economics; D017023:Coronary Angiography / Q000191:economics*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000191:economics*; D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed / Q000191:economics*