Improvement of C-reactive protein levels and body temperature of an elderly patient infected with Pseudomonas aeruginosa on treatment with Mao-bushi-saishin-to.
OBJECTIVE
To examine the effectiveness of Mao-bushi-saishin-to (Ma-Huang-Fu-Zi-Xi-Xin-Tang in Chinese medicine) (Tochimototenkaido Co. Ltd., Osaka, Japan), one of the traditional herbal medicines, against resistant bacterial infection.


METHODS
The Nursing Center Himawari, Izumo, Japan DESIGN, PATIENT, AND PREPARATION: Half of the standard dose of Mao-bushi-saishin-to was prescribed for 7 days to one elderly patient with fever and positive C-reactive protein (CRP) levels suffering from drug resistant Pseudomonas aeruginosa. The daily standard dose of Mao-bushi-saishin-to is prepared from 1200 mg of dried extract obtained from three crude drugs, Ephedrae Herba (4 g), Asiasari Radix (3 g), and Aconiti Tuber (1 g). It is certified by the Japanese Ministry of Health and Welfare.


RESULTS
The patient's fever and CRP level returned to normal levels.


CONCLUSIONS
In cases in which the fever does not fall in response to antibiotics for at least 3 days, half of the standard dose of Mao-bushi-saishin-to for 7 days might be worth trying to induce remission, especially for elder patients.
Kamei
T
T
Shimane Institute of Health Science, Izumo, Japan. kamei@nanken.shimane-med.ac.jp
Kondoh
T
T
Nagura
S
S
Toriumi
Y
Y
Kumano
H
H
Tomioka
H
H
D000368:Aged; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001831:Body Temperature; D002097:C-Reactive Protein / Q000378:metabolism*; D004352:Drug Resistance, Microbial; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D005334:Fever / Q000188:drug therapy; D006801:Humans; D009894:Opportunistic Infections / Q000188:drug therapy*; D011552:Pseudomonas Infections / Q000188:drug therapy*; D011550:Pseudomonas aeruginosa; D014552:Urinary Tract Infections / Q000188:drug therapy*
D000893:Anti-Inflammatory Agents; D004365:Drugs, Chinese Herbal; C119422:mao-bushi-saishin-to; D002097:C-Reactive Protein