The use of growth factors in cartilage repair.
Articular cartilage, which enables smooth gliding of joints during skeletal motion, is vulnerable to injuries and degenerative diseases over time. Bone growth factors have a role in the preservation of the cartilage matrix. This article reviews the potential to treat cartilage damage for bone morphogenetic proteins, insulin-like growth factors, hepatocyte growth factor, basic fibroblast growth factor, and transforming growth factor beta.
O'Connor
W J
WJ
Department of Orthopedic Surgery, Hospital for Special Surgery, New York, New York 10021, USA.
Botti
T
T
Khan
S N
SN
Lane
J M
JM
D000818:Animals; D002358:Cartilage, Articular / Q000293:injuries* / Q000503:physiopathology; D006133:Growth Substances / Q000008:administration & dosage* / Q000502:physiology; D006801:Humans; D010003:Osteoarthritis / Q000503:physiopathology / Q000628:therapy*; D011379:Prognosis
D006133:Growth Substances