title: Squamous cell carcinoma arising in Hailey-Hailey disease.
abstract: Hailey-Hailey disease is a recurrent, autosomal dominant vesiculobullous dermatotis with a predilection for intertrigenous areas. We report what we believe to be the first case of squamous cell carcinoma arising de novo in a skin lesion of Hailey-Hailey disease. The occurrence of malignant neoplasms arising in the skin lesions of Hailey-Hailey disease and other acantholytic dermatoses is reviewed.
authors.affiliation: Departments of Pathology and Dermatology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908-0214, USA.
authors.forename: V A
authors.initials: VA
authors.lastname: Holst
authors.forename: K P
authors.initials: KP
authors.lastname: Fair
authors.forename: B B
authors.initials: BB
authors.lastname: Wilson
authors.forename: J W
authors.initials: JW
authors.lastname: Patterson
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D016506:Pemphigus, Benign Familial / Q000473:pathology*; D012867:Skin / Q000473:pathology; D014844:Vulva / Q000473:pathology; D014846:Vulvar Neoplasms / Q000473:pathology*