title: Noise reduction in 3D perfusion imaging by attenuating the static signal in arterial spin tagging (ASSIST).
abstract: Phase-encoded multishot SPIRAL approaches were used to acquire true 3D cerebral blood flow images of the human head using arterial spin tagging approaches. Multiple-inversion background suppression techniques, which suppress phase noise due to interacquisition fluctuations in the static magnetic field, reduced the temporal standard deviation of true 3D delta M images acquired using arterial spin tagging approaches by approximately 50%. Background suppressed arterial spin tagging (ASSIST) approaches were used to obtain high-resolution isotropic true 3D cerebral blood flow images, and to obtain true 3D activation images during cognitive (working memory) tasks. Magn Reson Med 44:92-100, 2000. Published 2000 Wiley-Liss, Inc.
authors.affiliation: Clinical Brain Disorders Branch, NIMH, Bethesda, Maryland, USA.
authors.forename: F Q
authors.initials: FQ
authors.lastname: Ye
authors.forename: J A
authors.initials: JA
authors.lastname: Frank
authors.forename: D R
authors.initials: DR
authors.lastname: Weinberger
authors.forename: A C
authors.initials: AC
authors.lastname: McLaughlin
mesh_terms: D000328:Adult; D016477:Artifacts; D002536:Cerebral Arteries / Q000033:anatomy & histology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D019047:Phantoms, Imaging; D013113:Spin Labels; D013997:Time Factors
chemical_list: D013113:Spin Labels