[Multinodular goiter and parotid carcinoma : a new case of Cowden's disease].
Cowden's Disease is an autosomal dominant genodermatosis associated with abnormalities of the breast, thyroid gland, gastrointestinal tract. We describe a 23-year-old girl who was diagnosed with this disease when she consulted for evaluation of a multinodular goiter. Further investigations revealed breast lesions, gastric polyposis and parotid cancer. Recognizing Cowden's disease is important for prompt screening for malignancies. Skin lesions are markers of precancerous development.
Kacem
M
M
Service de Médecine Interne et de Néphrologie, Monastir, Tunisie.
Zili
J
J
Zakhama
A
A
Hadj Youssef
F
F
Mahjoub
S
S
Boubakri
C
C
El May
M
M
D000328:Adult; D001941:Breast Diseases / Q000150:complications / Q000175:diagnosis; D005260:Female; D006044:Goiter, Nodular / Q000150:complications*; D006223:Hamartoma Syndrome, Multiple / Q000175:diagnosis*; D006801:Humans; D006965:Hyperplasia; D008046:Lip; D009092:Mucous Membrane / Q000473:pathology; D010307:Parotid Neoplasms / Q000150:complications* / Q000175:diagnosis; D011127:Polyps / Q000150:complications / Q000175:diagnosis; D012867:Skin / Q000473:pathology; D013274:Stomach Neoplasms / Q000150:complications / Q000175:diagnosis