Neural induction.
Development of neural fates from ectoderm is accompanied by the blockage of BMP signals at both protein and mRNA levels. Recent work has employed zebrafish, chick and mouse in addition to amphibians as models. Genetics has supplemented experimental embryology in enriching the understanding of the mechanism of neural induction and in posing new questions.
Harland
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Department of Molecular and Cell Biology, University of California, Berkeley 94720-3204, USA. harland@socrates.berkeley.edu
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000037:antagonists & inhibitors; D003598:Cytoskeletal Proteins / Q000378:metabolism; D004475:Ectoderm / Q000502:physiology; D004627:Embryonic Induction / Q000502:physiology*; D008648:Mesoderm / Q000502:physiology; D051379:Mice; D020897:Organizers, Embryonic / Q000502:physiology; D011518:Proto-Oncogene Proteins / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*; D015534:Trans-Activators; D051153:Wnt Proteins; D029961:Zebrafish Proteins; D051176:beta Catenin
D019485:Bone Morphogenetic Proteins; C495267:CTNNB1 protein, mouse; D003598:Cytoskeletal Proteins; D011518:Proto-Oncogene Proteins; D015534:Trans-Activators; D051153:Wnt Proteins; D029961:Zebrafish Proteins; D051176:beta Catenin; C094522:wnt8b protein, zebrafish