title: Long-term results of wide surgical excision in 106 patients with hidradenitis suppurativa.
abstract: BACKGROUND
  Hidradenitis suppurativa (acne inversa) is a chronic recurrent disorder characterized by abscessing inflammation, fistulating sinus tracts, and scarring. Predilection sites are the intertriginal regions. The severe course of the disease demands an early and curative treatment.
  
  
  OBJECTIVE
  The aim of this study was to review the effect of radical surgical excision concerning cure rate and potential complications within a large group of patients.
  
  
  METHODS
  We analyzed data for 106 patients suffering from hidradenitis suppurativa treated during the period 1980-1998. The mean duration of the disease was 7 years. In about 90% of the cases, two or more sites were affected. Inguinal (70.8%) and axillary regions (61.3%) were most commonly involved. All patients were treated by radical wide excision using intraoperative marking of sinus tracts with methylviolet solution. The method of reconstruction depended on the size and location of the defect. Median postoperative follow-up time was 36 months.
  
  
  RESULTS
  The overall complication rate was 17.8%. Most of these were minor complications such as suture dehiscence, postoperative bleeding, and hematoma. Wound infection occurred in only 3.7% of patients. The rate of recurrence within the operated fields was 2.5%. There was no relation between the surgical method of reconstruction and the rate of recurrence. Recurrence was related to the severity of the disorder.
  
  
  CONCLUSIONS
  Our results confirm early radical excision as the treatment of choice for hidradenitis suppurativa. Using intraoperative color-marking of sinus tracts, the recurrence rate is minimal. The method of reconstruction has no influence on recurrence and should be chosen with respect to the size and location of the excised area.
authors.affiliation: Department of Dermatology, Klinikum Kassel, Kassel, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Rompel
authors.forename: J
authors.initials: J
authors.lastname: Petres
mesh_terms: D000328:Adult; D005260:Female; D016575:Hidradenitis / Q000601:surgery*; D006801:Humans; D008297:Male; D008722:Methods; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures; D013492:Suppuration; D016896:Treatment Outcome