Haploinsufficiency of the melanocortin-4 receptor: part of a thrifty genotype?
Cone
R D
RD
Vollum Institute, Oregon Health Sciences University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97201, USA. cone@ohsu.edu
D000483:Alleles; D004734:Energy Metabolism / Q000235:genetics; D005787:Gene Frequency; D006801:Humans; D020738:Leptin / Q000378:metabolism; D009154:Mutation; D009767:Obesity, Morbid / Q000235:genetics*; D010375:Pedigree; D011333:Pro-Opiomelanocortin / Q000378:metabolism; D044105:Receptor, Melanocortin, Type 4; D018000:Receptors, Peptide / Q000235:genetics*
D020738:Leptin; D044105:Receptor, Melanocortin, Type 4; D018000:Receptors, Peptide; D011333:Pro-Opiomelanocortin