title: Interventions for treating trichomoniasis in women.
abstract: BACKGROUND
  Around 120 million women worldwide suffer from Trichomonas vaginalis vaginitis every year. The infection is sexually transmitted and is believed to facilitate HIV transmission.
  
  
  OBJECTIVE
  To assess the effects of various treatment strategies for trichomoniasis in women.
  
  
  METHODS
  We searched the Cochrane Controlled Trials Register, MEDLINE, and EMBASE. Trials were also identified from reference lists of reviews, through pharmaceutical companies, and by informal discovery. Only published data were used in this review. Date of the most recent search: May, 2000.
  
  
  METHODS
  Randomised or quasi-randomised trials of different treatment strategies in women with trichomoniasis. Different antitrichomonal drugs or doses were eligible, as were comparisons of treatment with no treatment or placebo.
  
  
  METHODS
  Trial quality was assessed and data extracted by two reviewers independently using standard criteria.
  
  
  RESULTS
  Fifty-three trials were included. Nitroimidazole drugs seem to be effective in achieving parasitological cure in short term follow up. Partner treatment can be effective in decreasing longer term reinfection rates.
  
  
  CONCLUSIONS
  Parasitological cure can be achieved by single oral dose of nitroimidazoles. Further research should focus on developing effective partner treatment strategies to prevent reinfections and reduce trichomoniasis prevalence.
authors.affiliation: Department of Gynecology and Obstetrics, Emory University School of Medicine, 69 Butler Street, S.E., Atlanta, Georgia, USA, 30303. fatuforna@hotmail.com
authors.forename: F
authors.initials: F
authors.lastname: Forna
authors.forename: A M
authors.initials: AM
authors.lastname: Gülmezoglu
mesh_terms: D000818:Animals; D000994:Antitrichomonal Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use; D009593:Nitroimidazoles / Q000627:therapeutic use; D014247:Trichomonas Vaginitis / Q000188:drug therapy*
chemical_list: D000994:Antitrichomonal Agents; D009593:Nitroimidazoles; D008795:Metronidazole