title: Dedifferentiated liposarcoma with chondroblastic osteosarcomatous dedifferentiation.
abstract: We describe a rare case of dedifferentiated liposarcoma with features resembling chondroblastic osteosarcoma in the dedifferentiated component. The tumor was removed from the left thigh in a 78-year-old male. It consisted of a well-differentiated liposarcoma and an anaplastic component that contained numerous osteoid and cartilaginous tissues surrounded by high-grade spindle cell sarcoma. To our knowledge, only two cases similar to the divergent chondroblastic osteosarcomatous dedifferentiation of this disease have been reported in the literature.
authors.affiliation: Department of Orthopaedic Surgery, Kobe University School of Medicine, Kobe, Japan. yamatetu@med.kobe-u.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Matsushita
authors.forename: T
authors.initials: T
authors.lastname: Marui
authors.forename: K
authors.initials: K
authors.lastname: Mizuno
authors.forename: R
authors.initials: R
authors.lastname: Minami
authors.forename: Y
authors.initials: Y
authors.lastname: Hayashi
authors.forename: K
authors.initials: K
authors.lastname: Hanioka
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001859:Bone Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D002454:Cell Differentiation; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008080:Liposarcoma / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D008175:Lung Neoplasms / Q000556:secondary / Q000601:surgery; D008297:Male; D009363:Neoplasm Proteins / Q000032:analysis; D012516:Osteosarcoma / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D011879:Radiotherapy Dosage; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins