Cervical versus thoracic epidural morphine for the treatment of head and neck cancer pain.
We studied 29 patients in the final stage of head or neck cancer who were suffering pain that was not relieved by oral morphine. Cervical or thoracic epidural morphine was administered to relieve the pain. The quality of analgesia was equally good for both techniques. However, cervical epidural administration appeared to be superior, because much smaller doses of morphine were required in order to induce more rapid and longer analgesia.
Georgiou
L
L
Department of Anesthesiology, Hippokration General Hospital, Athens, Greece.
Louizos
A
A
Sklavou
C
C
Manolopoulos
L
L
Yiotakis
I
I
Adamopoulos
G
G
D000368:Aged; D015360:Analgesia, Epidural / Q000009:adverse effects / Q000379:methods*; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006258:Head and Neck Neoplasms / Q000150:complications*; D006801:Humans; D008297:Male; D009020:Morphine / Q000008:administration & dosage* / Q000009:adverse effects; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D010147:Pain Measurement
D000701:Analgesics, Opioid; D009020:Morphine