title: [Enzyme clearance in intermittent hemofiltration in patients with acute renal failure].
abstract: OBJECTIVE
  To characterize elimination of some enzymes in intermittent hemofiltration (HF) in patients with acute renal failure (ARF).
  
  
  METHODS
  22 patients with oliguric ARF have undergone 52 procedures of intermittent HF. Before the procedure and after it the activity of enzymes (AA, AP, ACE, LAP, GGT, GDG, AlAT, AsAT, CPG, LDG) was measured in the samples of plasma and filtrate.
  
  
  RESULTS
  Besides ACE and AlAT, all the enzymes concentrations were elevated in all the patients. HF did not change significantly the enzymes activity. Most of the enzymes were eliminated from the blood. In some samples the enzymes activity was low or absent.
  
  
  CONCLUSIONS
  Further studies are necessary to answer questions aroused by the findings.
authors.forename: V S
authors.initials: VS
authors.lastname: Timokhov
authors.forename: I V
authors.initials: IV
authors.lastname: Kazakov
authors.forename: S N
authors.initials: SN
authors.lastname: Selezneva
authors.forename: I V
authors.initials: IV
authors.lastname: Komissarova
authors.forename: L M
authors.initials: LM
authors.lastname: Smirnova
mesh_terms: D058186:Acute Kidney Injury / Q000201:enzymology* / Q000628:therapy; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000032:analysis / Q000097:blood; D015314:Dialysis Solutions / Q000737:chemistry*; D018450:Disease Progression; D004798:Enzymes / Q000032:analysis / Q000097:blood*; D005260:Female; D006440:Hemofiltration / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D015314:Dialysis Solutions; D004798:Enzymes