title: A practical large-scale synthesis of 17alpha-acetoxy-11beta-(4-N, N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione (CDB-2914).
abstract: A new practical synthesis of 17alpha-acetoxy-11beta-(4-N, N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione (CDB-2914) is described. The synthesis gives easily isolable solids at all steps and is amenable to large-scale process.
authors.affiliation: Department of Organic Chemistry, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX 78245-0549, USA. pnrao@sfbr.org
authors.forename: P N
authors.initials: PN
authors.lastname: Rao
authors.forename: C K
authors.initials: CK
authors.lastname: Acosta
authors.forename: M L
authors.initials: ML
authors.lastname: Bahr
authors.forename: J E
authors.initials: JE
authors.lastname: Burdett
authors.forename: J W
authors.initials: JW
authors.lastname: Cessac
authors.forename: P A
authors.initials: PA
authors.lastname: Morrison
authors.forename: H K
authors.initials: HK
authors.lastname: Kim
mesh_terms: D002855:Chromatography, Thin Layer / Q000379:methods; D003283:Contraceptives, Postcoital, Synthetic / Q000138:chemical synthesis* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D009649:Norpregnadienes / Q000138:chemical synthesis* / Q000302:isolation & purification; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods
chemical_list: D003283:Contraceptives, Postcoital, Synthetic; D009649:Norpregnadienes; C094854:ulipristal