title: Frontal sinus adenocarcinoma.
abstract: BACKGROUND
  Paranasal sinus cancer is considered rare, with an incidence of less than 1 per 100,000 per year, with the frontal sinus being the primary site in only 0.3%. We report a case of adenocarcinoma arising in the frontal sinus.
  
  
  METHODS
  Case report.
  
  
  METHODS
  A 59-year-old woman, secretary, came in February 1998 with a 4-month history of low intensity frontal headache. She denied contact with wood dust. On examination a non-tender swelling was noted over her right forehead next to the medial aspect of the right orbit. CT scan showed a soft-tissue mass involving frontal sinus with intracranial invasion through the posterior wall. The anterior ethmoid sinus and the medial aspect of the right orbit were also involved. MRI demonstrated dural thickening in communication with the frontal mass. She underwent an en-bloc tumor resection by craniotomy including orbital clearance. Histology revealed an adenocarcinoma. After surgery she had tumor recurrence, and chemotherapy and radiotherapy were started resulting in partial improvement.
authors.affiliation: Department of Otorhinolaryngology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
authors.forename: M
authors.initials: M
authors.lastname: Abrahão
authors.forename: A P
authors.initials: AP
authors.lastname: Gonçalves
authors.forename: R
authors.initials: R
authors.lastname: Yamashita
authors.forename: R A
authors.initials: RA
authors.lastname: Dedivitis
authors.forename: R O
authors.initials: RO
authors.lastname: Santos
authors.forename: L A
authors.initials: LA
authors.lastname: Nascimento
authors.forename: M L
authors.initials: ML
authors.lastname: Mudo
authors.forename: F A
authors.initials: FA
authors.lastname: Ferraz
authors.forename: O
authors.initials: O
authors.lastname: Cervantes
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D005260:Female; D005626:Frontal Sinus; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed