title: Body-plan evolution in the Bilateria: early antero-posterior patterning and the deuterostome-protostome dichotomy.
abstract: Recent molecular analyses reveal common themes in early antero-posterior patterning in the four major groups of invertebrate deuterostomes and vertebrates in spite of large differences in the mode of gastrulation. Comparisons with Drosophila and Cnidarians suggest a scheme for evolution of the Bilaterian body plan and emphasize the pressing need for similar studies in a wider variety of organisms, especially more basal protostomes.
authors.affiliation: Marine Biology Research Division, Scripps Institution of Oceanography, University of California at San Diego, 92093-0202, USA. lzholland@ucsd.edu
authors.forename: L Z
authors.initials: LZ
authors.lastname: Holland
mesh_terms: D000818:Animals; D005075:Biological Evolution; D015415:Biomarkers; D019521:Body Patterning / Q000235:genetics* / Q000502:physiology; D029721:Drosophila Proteins; D005326:Fetal Proteins; D005775:Gastrula / Q000502:physiology; D015870:Gene Expression; D018398:Homeodomain Proteins / Q000502:physiology; D011518:Proto-Oncogene Proteins / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology; D020825:T-Box Domain Proteins / Q000502:physiology; D014157:Transcription Factors; D051153:Wnt Proteins; D029961:Zebrafish Proteins; D000098908:Brachyury Protein
chemical_list: D015415:Biomarkers; D029721:Drosophila Proteins; D005326:Fetal Proteins; D018398:Homeodomain Proteins; D011518:Proto-Oncogene Proteins; D020825:T-Box Domain Proteins; D014157:Transcription Factors; D051153:Wnt Proteins; D029961:Zebrafish Proteins; D000098908:Brachyury Protein; C084564:cad protein, Drosophila