Hypophosphatemia secondary to oral refeeding in anorexia nervosa.
OBJECTIVE
Hypophosphatemia is a well-known complication of the refeeding syndrome in severe cases of anorexia nervosa, described mostly as a result of refeeding with total parenteral nutrition. Few cases have been reported secondary to either nasogastric or oral refeeding.


METHODS
The authors present three cases in which hypophosphatemia developed secondary to oral refeeding in severe anorexia nervosa.


RESULTS
All 3 patients developed significant hypophosphatemia, to a low of 0.9 mg/dl in two cases and a low of 1. 7 mg/dl in the third. The first patient received close to 3,000 calories per day, along with intravenous fluids, in the hospital; the other 2 patients ate large amounts for several days at home. Caloric restriction and replenishment with phosphorous resulted in a rapid return of phosphorous values to normal levels.


CONCLUSIONS
Those who treat severely malnourished patients with eating disorders, whether as inpatients or outpatients, need to be vigilant for the development of the refeeding syndrome, even in patients receiving oral refeeding alone.
Fisher
M
M
Division of Adolescent Medicine, North Shore University Hospital, Manhasset, New York 11030, USA.
Simpser
E
E
Schneider
M
M
D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000150:complications / Q000628:therapy*; D004435:Eating; D005260:Female; D006801:Humans; D017674:Hypophosphatemia / Q000209:etiology*; D009748:Nutrition Disorders; D018529:Nutritional Support; D010758:Phosphorus / Q000008:administration & dosage
D010758:Phosphorus