Granulomatous myositis, primary biliary cirrhosis, pancytopenia, and thymoma.
Granulomatous myopathies are rare. Most cases are associated with sarcoidosis. We report a case of granulomatous myopathy associated with primary biliary cirrhosis, pancytopenia, and thymoma. The literature in regard to granulomatous myopathy and its pathogenesis is reviewed. Intermittent pulsed intravenous methylprednisolone may be useful as maintenance therapy for granulomatous myopathy and other neuromuscular syndromes for patients intolerant of oral corticosteroids.
Herrmann
D N
DN
Department of Neurology, University of Rochester, SMH 601 Elmwood Ave., Box 673, Rochester, New York 14642, USA. David_Herrmann@urmc.rochester.edu
Blaivas
M
M
Wald
J J
JJ
Feldman
E L
EL
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006099:Granuloma / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology; D009220:Myositis / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D010198:Pancytopenia / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D013945:Thymoma / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D013953:Thymus Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D014057:Tomography, X-Ray Computed
D000893:Anti-Inflammatory Agents; D011241:Prednisone