A SNPshot: pharmacogenetics and the future of drug therapy.
Pharmacogenetics holds great promise for the optimization of new drug development and the individualization of clinical therapeutics in the 21st century. In this brief review, we trace the historical roots of pharmacogenetics, discuss its rapidly evolving processes and paradigms, and look towards future applications of pharmacogenetics in enhancing the efficiency of the drug development pipeline and in improving patient care.
Pfost
D R
DR
Orchid BioSciences, Princeton, NJ 08540, USA. dpfost@orchid.com
Boyce-Jacino
M T
MT
Grant
D M
DM
D004358:Drug Therapy / Q000639:trends*; D010597:Pharmacogenetics; D020641:Polymorphism, Single Nucleotide