title: Diagnosis of acute appendicitis: comparison of 5- and 10-mm CT sections in the same patient.
abstract: OBJECTIVE
  To compare 5- and 10-mm computed tomographic (CT) sections in the same patient to diagnose acute appendicitis.
  
  
  METHODS
  During an 11-month period, 100 consecutive patients clinically suspected to have acute appendicitis underwent abdominal and pelvic CT. Helical, 10-mm-collimated sections from the diaphragm to the pubic symphysis and 5-mm-collimated sections through the lower part of the abdomen and upper part of the pelvis were obtained. The 10- and 5-mm sections from each patient were separated into two groups and were interpreted independently by two abdominal imaging attending physicians who were blinded to the final results. The interpretations were correlated with the histopathologic or final clinical diagnoses.
  
  
  RESULTS
  Data analysis from blinded reader interpretations of the 5- and 10-mm sections, respectively, revealed sensitivities of 99% and 82% (P <.001), specificities of 98% and 95% (P =.426), and accuracies of 99% and 89% (P <.001). Among the 48 cases of acute appendicitis, abnormal appendices were identified in 94% (n = 45) and 69% (n = 33) (P <.05) on 5- and 10-mm-collimated sections, respectively. Right-lower-quadrant inflammatory changes were identified in 98% (n = 47) and 71% (n = 34) (P <.05) on 5- and 10-mm-collimated sections, respectively. Normal appendices were identified in 75% (n = 39) and 52% (n = 27) of the 52 negative cases on 5- and 10-mm sections (P =.025), respectively.
  
  
  CONCLUSIONS
  Use of thin-section CT significantly improves the diagnosis of acute appendicitis.
authors.affiliation: Department of Radiology, Nassau County Medical Center, 2201 Hempstead Turnpike, East Meadow, NY 11554, USA. dweltman@ncmc.edu
authors.forename: D I
authors.initials: DI
authors.lastname: Weltman
authors.forename: J
authors.initials: J
authors.lastname: Yu
authors.forename: J
authors.initials: J
authors.lastname: Krumenacker
authors.forename: S
authors.initials: S
authors.lastname: Huang
authors.forename: P
authors.initials: P
authors.lastname: Moh
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D001064:Appendicitis / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003287:Contrast Media