title: Congestive heart failure and myocarditis after seroconversion for toxoplasmosis in two immunocompetent patients.
abstract: Two cases of myocarditis and congestive heart failure in immunocompetent patients with seroconversion for toxoplasmosis are reported. Serological tests showed that in the first case the cardiac manifestations occurred at the time of seroconversion (low IgG, raised IgM and IgA), whereas in the second case they occurred several months after the initial infection when IgM was decreasing, IgG levels were very high (>1000 IU/ml) and IgG had high affinity for the antigen. The pathophysiological mechanisms underlying cardiac involvement in acute or chronic toxoplasmosis are discussed.
authors.affiliation: Service de Parasitologie-Mycologie, CHU d'Amiens, Hôpital Sud, France. jac-bri.chandenier@wanadoo.fr
authors.forename: J
authors.initials: J
authors.lastname: Chandenier
authors.forename: G
authors.initials: G
authors.lastname: Jarry
authors.forename: D
authors.initials: D
authors.lastname: Nassif
authors.forename: Y
authors.initials: Y
authors.lastname: Douadi
authors.forename: L
authors.initials: L
authors.lastname: Paris
authors.forename: P
authors.initials: P
authors.lastname: Thulliez
authors.forename: E
authors.initials: E
authors.lastname: Bourges-Petit
authors.forename: C
authors.initials: C
authors.lastname: Raccurt
mesh_terms: D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D002648:Child; D005260:Female; D006333:Heart Failure / Q000209:etiology* / Q000469:parasitology / Q000503:physiopathology; D006801:Humans; D007121:Immunocompetence; D009205:Myocarditis / Q000209:etiology* / Q000469:parasitology / Q000503:physiopathology; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000150:complications* / Q000469:parasitology
chemical_list: D000913:Antibodies, Protozoan