The effect of thymol and its derivatives on reactions generating reactive oxygen species.
The effects of thymol (TOH), thymoquinone (TQ) and dithymoquinone (TQ2) on the reactions generating reactive oxygen species (ROS) such as superoxide anion radical (O2*-), hydroxyl radical (HO*) and singlet oxygen (1O2) were tested using the chemiluminescence (CL) and spectrophotometry methods. All tested compounds acted as scavengers of various ROS. The rate constant of 1O2-dimols quenching by thymol was calculated.
Kruk
I
I
Institute of Physics, Technical University of Szczecin, Poland. klich@arcadia.tuniv.szczecin.pl
Michalska
T
T
Lichszteld
K
K
Kładna
A
A
Aboul-Enein
H Y
HY
D000890:Anti-Infective Agents / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D016227:Benzoquinones / Q000494:pharmacology*; D005609:Free Radicals; D008163:Luminescent Measurements; D017382:Reactive Oxygen Species / Q000378:metabolism; D013053:Spectrophotometry; D013943:Thymol / Q000494:pharmacology*
D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D016227:Benzoquinones; D005609:Free Radicals; D017382:Reactive Oxygen Species; C113528:dithymoquinone; D013943:Thymol; C003466:thymoquinone