title: Calcified left ventricular mass: unusual clinical, echocardiographic, and computed tomographic findings of primary cardiac osteosarcoma.
abstract: Primary cardiac osteosarcomas are rare and usually originate in the left atrium. In contrast, osteosarcomas metastatic to the heart most commonly involve the right cardiac chambers. This case report describes an unusual primary cardiac osteosarcoma, initially observed as a slowly growing, densely calcified mass of the left ventricle with subsequent secondary pulmonary metastasis. Although cardiac tumors may be asymptomatic, this patient had recurrent bouts of ventricular tachyarrhythmia. We describe the clinical, echocardiographic, and radiological observations spanning 6 years and the gross and microscopic features at autopsy.
authors.affiliation: Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester MN 55905, USA.
authors.forename: S K
authors.initials: SK
authors.lastname: Nowrangi
authors.forename: N M
authors.initials: NM
authors.lastname: Ammash
authors.forename: W D
authors.initials: WD
authors.lastname: Edwards
authors.forename: J F
authors.initials: JF
authors.lastname: Breen
authors.forename: J H
authors.initials: JH
authors.lastname: Edmonson
mesh_terms: D002114:Calcinosis / Q000175:diagnosis* / Q000473:pathology; D009202:Cardiomyopathies / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D004452:Echocardiography; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged; D012516:Osteosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D017180:Tachycardia, Ventricular / Q000209:etiology; D014057:Tomography, X-Ray Computed