title: Infants exposed to MRI in utero have a normal paediatric assessment at 9 months of age.
abstract: Any differences in detailed paediatric assessment at 9 months of age in infants exposed to echo planar MRI in utero from 20 weeks gestation to term were investigated by performing a case controlled prospective observational study of 20 infants. They had all had serial echo planar MRI in the antenatal period and were compared with a control group born at the same time who had not. Statistical analysis employed likelihood ratios, odds ratios and 95% confidence intervals. The mothers of the control infants had a significantly higher standard of educational attainment (p = 0.005). A small but significant decrease in length (p = 0.047), and an increase in gross motor function (p = 0.023) of the fetuses exposed to echo planar imaging were demonstrated. No other significant developmental or social differences were seen between the two groups. Infants at 9 months of age did not demonstrate any gross abnormality likely to be related to exposure to echo planar MRI in utero.
authors.affiliation: School of Human Development, University of Nottingham, UK.
authors.forename: H
authors.initials: H
authors.lastname: Clements
authors.forename: K R
authors.initials: KR
authors.lastname: Duncan
authors.forename: K
authors.initials: K
authors.lastname: Fielding
authors.forename: P A
authors.initials: PA
authors.lastname: Gowland
authors.forename: I R
authors.initials: IR
authors.lastname: Johnson
authors.forename: P N
authors.initials: PN
authors.lastname: Baker
mesh_terms: D001827:Body Height / Q000528:radiation effects; D016022:Case-Control Studies; D002657:Child Development / Q000528:radiation effects*; D016001:Confidence Intervals; D017352:Echo-Planar Imaging / Q000009:adverse effects; D005260:Female; D006801:Humans; D007223:Infant; D016013:Likelihood Functions; D016017:Odds Ratio; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011297:Prenatal Exposure Delayed Effects; D011446:Prospective Studies