title: Phosphinooxazolines--a new class of versatile, modular P,N-ligands for asymmetric catalysis.
abstract: Chiral phosphinooxazolines (PHOX ligands), which coordinate to a metal center with a N- and a P-atom, allow effective enantiocontrol in a variety of metal-catalyzed reactions. They are readily synthesized, and because of their modular structure, the steric and electronic properties can be tailored for a specific application by variation of the oxazoline ring, the backbone, and the phosphine moiety.
authors.affiliation: Institut für Organische Chemie, Universität Heidelberg, Im Neuenheimer Feld 270, D-69120 Heidelberg, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Helmchen
authors.forename: A
authors.initials: A
authors.lastname: Pfaltz
mesh_terms: D002384:Catalysis; D008024:Ligands; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000138:chemical synthesis / Q000737:chemistry; D010080:Oxazoles / Q000138:chemical synthesis / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D010720:Phosphines / Q000138:chemical synthesis / Q000737:chemistry*; D012413:Rubidium / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D008024:Ligands; D009942:Organometallic Compounds; D009943:Organophosphorus Compounds; D010080:Oxazoles; D010720:Phosphines; D010165:Palladium; D012413:Rubidium