Application of derivative UV spectrophotometry for the determination of enoxacin and nalidixic acid in tablets.
First-, second-, third- and forth-order derivative spectrophotometric methods, using "peak-zero" (P-O) and "peak-peak" (P-P) techniques of measurement have been developed for the determination of enoxacin and nalidixic acid in tablets. The calibration curves were linear in the concentration range of 2.0-12.0 micrograms ml-1 for the analysed quinolones. The procedure was simple, rapid and the results were reliable.
Hopkała
H
H
Department of Medicinal Chemistry, Medical Academy, Lublin, Poland.
Kowalczuk
D
D
D000890:Anti-Infective Agents / Q000032:analysis*; D002138:Calibration; D015365:Enoxacin / Q000032:analysis*; D007202:Indicators and Reagents; D009268:Nalidixic Acid / Q000032:analysis*; D012044:Regression Analysis; D013056:Spectrophotometry, Ultraviolet; D013607:Tablets
D000890:Anti-Infective Agents; D007202:Indicators and Reagents; D013607:Tablets; D015365:Enoxacin; D009268:Nalidixic Acid