Immediate surgery reduces mortality in deeply comatose patients with spontaneous cerebellar hemorrhage.
Cerebellar hemorrhage is regarded as a neurosurgical emergency. However, patients with deteriorating consciousness are very likely to die irrespective of the choice of therapy, and it is not clear if surgical intervention can benefit patients in a deeply comatose state. We reviewed 20 patients with a Glasgow Coma Scale score of 3 at admission to ascertain the salvage rate and determine the prognostic factors. Four patients who were managed conservatively died within 2 days. Sixteen patients underwent decompressive suboccipital craniectomy and hematoma evacuation. At discharge, three patients were moderately disabled, three were severely disabled, four were persistently vegetative, and six had died. The overall mortality was 50%. The mean interval between the onset of symptoms and the operation was 1.67 +/- 0.29 hours in patients with favorable outcome, and significantly longer at 2.42 +/- 0.49 hours in patients with an unfavorable outcome (p = 0.025). Immediate evacuation of the hematoma reduces morbidity and mortality even in deeply comatose patients, especially if the time interval between the onset and surgery is within 2 hours.
Yanaka
K
K
Department of Neurosurgery, Tsukuba Medical Center, Ibaraki.
Meguro
K
K
Fujita
K
K
Narushima
K
K
Nose
T
T
D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D002531:Cerebellum / Q000473:pathology* / Q000601:surgery*; D003128:Coma / Q000209:etiology*; D019299:Decompression, Surgical / Q000379:methods*; D005260:Female; D015600:Glasgow Coma Scale; D006406:Hematoma / Q000601:surgery; D006801:Humans; D020299:Intracranial Hemorrhage, Hypertensive / Q000150:complications / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome