[The lack of the CpNpG methylation at the 5'-terminal region of the human calcitonin gene in norm and in leukemia [].
The inner cytosine methylation was analyzed in the CCWGG sequences of the 5'-terminal region of the human calcitonin gene from peripheral blood and bone marrow cells in various forms of leukemia. Since these sequences remain nonmethylated both in norm and in various leukemia forms, the CpG dinucleotide hypermethylation of the 5'-terminus of the human calcitonin gene, characteristic for the development of leukemias, does not spread over adjacent CpNpG sequences.
Bur'ianov
Ia I
IaI
Shevchuk
T V
TV
Zakharchenko
N S
NS
D'iachenko
O V
OV
Marinich
D V
DV
Vorob'ev
I A
IA
D020121:5' Untranslated Regions; D002116:Calcitonin / Q000235:genetics*; D003596:Cytosine; D019175:DNA Methylation; D006801:Humans; D007938:Leukemia / Q000235:genetics*
D020121:5' Untranslated Regions; D003596:Cytosine; D002116:Calcitonin