title: [Solid and pseudopapillary tumor of the pancreas: immunohistochemical and ultrastructural study of 2 pediatric cases].
abstract: We report 2 cases of solid and pseudopapillary tumors of the pancreas occurring in female children. Lesions were made of uniform small cells arranged in solid areas associated with pseudopapillary and cystic patterns. Immunohistochemistry study was positive for neuron-specific enolase, alpha-1 anti-trypsin and vimentin. Ultrastructural study showed an abundant cytoplasm, rich in mitochondria, containing a lot of granules of variable sizes, often disintegrated, and some lipid droplets. The differential diagnosis of this lesion included endocrine tumor, pancreatoblastoma and acinar cell carcinoma. It is a rare tumor of the pancreas with a favorable prognosis after complete resection.
authors.affiliation: Service d'Anatomie Pathologique, Hôpital Pasteur, 30 avenue de la Voie Romaine, 06002 Nice.
authors.forename: O
authors.initials: O
authors.lastname: Lompo
authors.forename: V
authors.initials: V
authors.lastname: Hofman
authors.forename: C
authors.initials: C
authors.lastname: Soler
authors.forename: J S
authors.initials: JS
authors.lastname: Valla
authors.forename: J F
authors.initials: JF
authors.lastname: Michiels
authors.forename: P
authors.initials: P
authors.lastname: Bedossa
authors.forename: P
authors.initials: P
authors.lastname: Hofman
mesh_terms: D000293:Adolescent; D002291:Carcinoma, Papillary / Q000737:chemistry* / Q000648:ultrastructure*; D002648:Child; D003593:Cytoplasm / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008928:Mitochondria / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000737:chemistry* / Q000648:ultrastructure*; D010751:Phosphopyruvate Hydratase / Q000032:analysis; D014746:Vimentin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis
chemical_list: D014746:Vimentin; D000515:alpha 1-Antitrypsin; D010751:Phosphopyruvate Hydratase