title: [Chronic viral hepatitis and alcoholic liver: clinico-morphological correlations].
abstract: 69 patients with alcohol addiction infected with hepatitis viruses underwent clinical, laboratory and morphological examinations using light and electron microscopic studies of liver biopsies. Light microscopy revealed three variants of liver damage: viral, alcoholic and mixed. Both etiological factors affect manifestations and course of the disease as shown by electron microscopy in spite of morphological signs of only viral or mixed lesion. The lowest index of histological activity is found in combination alcohol + HCV, the highest index being in patients with HBV + HCV and HBV + HDV. Alcohol abuse in combination with HCV infection increases histological activity of liver damage.
authors.affiliation: Academician V. V. Serov's Group, I. M. Sechenov Moscow Medical Academy.
authors.forename: E L
authors.initials: EL
authors.lastname: Tanashchiuk
authors.forename: S M
authors.initials: SM
authors.lastname: Sekamova
authors.forename: V V
authors.initials: VV
authors.lastname: Serov
authors.forename: I V
authors.initials: IV
authors.lastname: Popova
mesh_terms: D019694:Hepatitis B, Chronic / Q000150:complications* / Q000473:pathology / Q000821:virology; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000473:pathology / Q000821:virology; D019701:Hepatitis D, Chronic / Q000150:complications* / Q000473:pathology / Q000821:virology; D006801:Humans; D008099:Liver / Q000473:pathology* / Q000648:ultrastructure / Q000821:virology; D008108:Liver Diseases, Alcoholic / Q000150:complications* / Q000473:pathology / Q000821:virology