Definition of inflammatory cardiomyopathy (myocarditis): on the way to consensus. A status report.
This article reviews the current state of consensus reached for the diagnosis of myocarditis and dilated cardiomyopathy on the basis of conventional histopathological and immunohistochemical methods for inflammatory infiltrates in addition to molecular biological methods for persistence of viral genome in endomyocardial biopsies. Additionally, a brief overview is presented stating the current knowledge on effector mechanisms of the immune system in myocarditis and dilated cardiomyopathy.
Maisch
B
B
Department of Internal Medicine-Cardiology, Philipps-University Marburg, Germany. maisch@mailer.uni-marburg.de
Portig
I
I
Ristic
A
A
Hufnagel
G
G
Pankuweit
S
S
D001323:Autoantibodies / Q000032:analysis; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D002908:Chronic Disease; D004699:Endocardium / Q000276:immunology / Q000473:pathology; D006801:Humans; D007958:Leukocyte Count; D009205:Myocarditis / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D009206:Myocardium / Q000276:immunology / Q000473:pathology; D014777:Virus Diseases / Q000175:diagnosis / Q000276:immunology / Q000473:pathology
D001323:Autoantibodies