Particles released from the Gyro C1E3 during simulated extracorporeal circulation.
Evaluation of released particles from the blood pump during extracorporeal circulation is an important aspect because the particles may cause microembolism. The Gyro C1E3 is a centrifugal blood pump that has an impeller suspended by double pivot bearings inside the housing; therefore, it is important to evaluate the released particles. The C1E3 was driven for 14 days to simulate clinical left ventricular assist device (LVAD) and percutaneous cardiopulmonary support (PCPS). Also, a roller pump was driven for 2 days as a comparison. Released particles were weighed and examined by SEM. After 14 days of pumping, the particles from the C1E3 were 238.6 microg in an LVAD condition. The particles with the roller pump were 270.2 microg after only 2 days. Average particle sizes with the roller pump and C1E3 were 3.7 and 0.6 microm, respectively. These results suggest that the Gyro C1E3 substantially reduces the risk of microembolism from released particles.
Takano
T
T
Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA. ttakano@bcm.tmc.edu
Nakata
K
K
Schulte-Eistrup
S
S
Kawahito
S
S
Glueck
J
J
Clarke
I C
IC
Williams
P A
PA
Maeda
T
T
Nonaka
K
K
Linneweber
J
J
Yoshikawa
M
M
Fujisawa
A
A
Makinouchi
K
K
Yokokawa
M
M
Nosé
Y
Y
D001672:Biocompatible Materials; D002498:Centrifugation; D004617:Embolism / Q000209:etiology; D004867:Equipment Design; D005112:Extracorporeal Circulation / Q000295:instrumentation*; D006353:Heart-Assist Devices; D006801:Humans; D008855:Microscopy, Electron, Scanning; D010316:Particle Size
D001672:Biocompatible Materials