Radiation-associated xanthomatous meningioma in a child.
Radiation-associated meningioma in a child is rare. We report a case of xanthomatous meningioma, a rare subtype even in the adult population, which occurred in a 10-year-old boy who had undergone irradiation therapy for ependymoma at the age of 2 years. Histological examination of the tumor revealed a mixture of meningothelial cells and abundant foamy xanthomatous cells, with no apparent atypical cellular features. Xanthomatous meningioma associated with therapeutic high-dose irradiation in a child has not yet been documented. Immunohistochemical studies and the clinical course are evaluated with a review of the literature.
Ijiri
R
R
Department of Pathology, Kanagawa Children Medical Center, Japan.
Tanaka
Y
Y
Hara
M
M
Sekido
K
K
D001932:Brain Neoplasms / Q000532:radiotherapy; D002648:Child; D016371:Cranial Irradiation / Q000009:adverse effects*; D019583:Dose Fractionation, Radiation; D004806:Ependymoma / Q000532:radiotherapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D008579:Meningioma / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis / Q000473:pathology*; D012086:Reoperation