title: Early identification and intervention in psychotic illness.
abstract: Early detection and intervention strategies in persons who present with recently developing "prodromal" symptoms that look like early versions of the symptoms of psychosis are being investigated at a special outpatient clinic at Yale Medical School. The study aims to test whether treatment, including newer antipsychotic medication, can treat these symptoms and, in addition, might prevent or delay the onset of psychosis. Here we describe the clinic, the study, and the symptoms to look for in patients who may be at high risk for becoming psychotic in the near future. We also discuss the practical and ethical ramifications of this promising new direction in the treatment of serious mental illness.
authors.affiliation: Yale University School of Medicine, Director, PRIME Research Center, New Haven, USA.
authors.forename: T J
authors.initials: TJ
authors.lastname: Miller
authors.forename: T H
authors.initials: TH
authors.lastname: McGlashan
mesh_terms: D000293:Adolescent; D000553:Ambulatory Care; D003237:Connecticut; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000628:therapy; D008605:Mental Health Services / Q000458:organization & administration*; D011322:Primary Prevention / Q000379:methods*; D016730:Program Development; D015397:Program Evaluation; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000517:prevention & control / Q000628:therapy*; D013997:Time Factors