title: Thiamphenicol in the treatment of chancroid. A study of 1,128 cases.
abstract: Thiamphenicol, an aminic derivate of hydrocarbilsulfonil propandiol, was used for the treatment of 1,171 chancroid bearing patients. Each patient was medicated with 5.0 g of granulated thiamphenicol, orally, in a single dose, and was reevaluated 3, 7 and 10 days after the treatment. Ten patients (0.89%) did not respond to the proposed treatment. 133 patients presented healed ulcers after 3 days of treatment, 976 patients healed chancres on the seventh day after the treatment, and 39 patients took 10 days to present healed chancres. The results of this study indicate that the rate of patients that were cured, the low incidence of side effects, and the practicality of administration make of thiamphenicol an excellent choice for the treatment of chancroid.
authors.affiliation: Department of Dermatology, Faculty of Medicine, University of S. Paulo, S. Paulo, SP, Brasil.
authors.forename: W
authors.initials: W
authors.lastname: Belda Junior
authors.forename: L F
authors.initials: LF
authors.lastname: Siqueira
authors.forename: L J
authors.initials: LJ
authors.lastname: Fagundes
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002602:Chancroid / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013839:Thiamphenicol / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D013839:Thiamphenicol