title: Current management of epithelial ovarian carcinoma: a review.
abstract: Epithelial carcinoma of the ovary is the most lethal of gynaecological malignancies and it affects about one in 70 women in developed countries. Over 75% of women with the disease have tumour spread beyond the pelvis at the time of diagnosis, and their treatment requires the appropriate use of surgery and chemotherapy. The strategies used in the treatment of ovarian cancer are constantly evolving. An overview of current treatment regimens and their evolution is provided, with particular emphasis on the interdependence of surgery and chemotherapy in the optimal management of the disease.
authors.affiliation: Gynaecological Cancer Centre, Royal Hospital for Women, Randwick, Australia. d.marsden@unsw.edu.au
authors.forename: D E
authors.initials: DE
authors.lastname: Marsden
authors.forename: M
authors.initials: M
authors.lastname: Friedlander
authors.forename: N F
authors.initials: NF
authors.lastname: Hacker
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018394:CA-125 Antigen / Q000097:blood; D002277:Carcinoma / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D007813:Laparotomy; D008197:Lymph Node Excision; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery*; D017671:Platinum Compounds / Q000627:therapeutic use; D012086:Reoperation
chemical_list: D018394:CA-125 Antigen; D017671:Platinum Compounds