Thiocyanate mediated antifungal and antibacterial property of goat milk lactoperoxidase.
Goat milk lactoperoxidase was purified using CM-Sephadex-C-50 ion exchange chromatography and Sephadex G-100 gel filtration. The purified protein was found to have high antifungal and antibacterial activity in a thiocyanate-H2O2 medium. The results are relevant enough to suggest the exploitation of LP-thiocyanate-H2O2 system as an effective agent against many of the disease causing organisms in plants and animals.
Benoy
M J
MJ
School of Biosciences, Mahatma Gandhi University, Kottayam.
Essy
A K
AK
Sreekumar
B
B
Haridas
M
M
D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects; D001419:Bacteria / Q000187:drug effects; D002175:Candida / Q000187:drug effects; D004347:Drug Interactions; D006041:Goats; D006861:Hydrogen Peroxide / Q000494:pharmacology; D007784:Lactoperoxidase / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D008892:Milk / Q000201:enzymology*; D010407:Penicillium / Q000187:drug effects; D013861:Thiocyanates / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D013861:Thiocyanates; D006861:Hydrogen Peroxide; D007784:Lactoperoxidase; C031760:thiocyanate