title: Cochleovestibular symptoms related to the site of vestibular schwannoma.
abstract: The purpose of the investigation was to study the symptoms that may provide clues to the early diagnosis of vestibular schwannoma (VS). The symptoms associated with VS in 41 patients were compared with the tumour locations detected by magnetic resonance imaging (MRI). There were 9 (22%) mainly intracanalicular and 32 (78%) mainly extracanalicular tumours. MRI visualized the enhancement of the intracanalicular nerve in 27 of 32 extracanalicular schwannomas. Hearing impairment was found as an initial symptom equally frequently in patients with intra- or extracanalicular VS. Tinnitus was reported as the first symptom more often in patients with extracanalicular VS and dizziness more often in patients with intracanalicular tumours. At the time of diagnosis, unilateral hearing loss was present in 98% of patients, independent of tumour location. Likewise, dizziness was found equally frequently in both patient groups. Instead, tinnitus was found almost significantly more frequently in patients with intracanalicular VS (p = 0.07). Although statistically insignificantly so, neurological symptoms were more common in patients with extracanalicular VS (p = 0.45).
authors.affiliation: Department of Otolaryngology, University Central Hospital of Turku, Finland. jorma haapaniemi@kaarina.fi
authors.forename: J
authors.initials: J
authors.lastname: Haapaniemi
authors.forename: E
authors.initials: E
authors.lastname: Laurikainen
authors.forename: R
authors.initials: R
authors.lastname: Johansson
authors.forename: S
authors.initials: S
authors.lastname: Miettinen
authors.forename: M
authors.initials: M
authors.lastname: Varpula
mesh_terms: D003051:Cochlea / Q000503:physiopathology; D004244:Dizziness / Q000175:diagnosis / Q000209:etiology*; D004424:Ear Canal / Q000473:pathology; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000150:complications* / Q000473:pathology*; D012720:Severity of Illness Index; D014012:Tinnitus / Q000175:diagnosis / Q000209:etiology*; D014722:Vestibule, Labyrinth / Q000503:physiopathology