title: Candida arthritis in a premature infant treated successfully with oral fluconazole for six months.
abstract: BACKGROUND
  Candida arthritis in premature infants is a rare condition mainly treated with parenteral amphotericin B.
  
  
  METHODS
  Arthritis 9 weeks after birth. The infection resulted out of colonisation at birth and fungaemia at day 6 and day 13 of life.
  
  
  METHODS
  Oral fluconazole for 6 months (5 mg/kg/day after loading with 7 mg/kg/day).
  
  
  RESULTS
  Full remission.
  
  
  CONCLUSIONS
  Oral fluconazole is an alternative to parenteral amphotericin B in the treatment of premature infants, but proof of absorption and an extended treatment period according to prematurity might be warranted.
authors.affiliation: Klinik für Allgemeine Pädiatrie, Kiel, Germany. weigl@pediatrics.uni-kiel.de
authors.forename: J A
authors.initials: JA
authors.lastname: Weigl
mesh_terms: D000284:Administration, Oral; D000935:Antifungal Agents / Q000627:therapeutic use*; D001170:Arthritis, Infectious / Q000175:diagnosis / Q000188:drug therapy*; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy*; D004334:Drug Administration Schedule; D015725:Fluconazole / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole