[Differential approach to administration of cosaar].
Effects of cosaar (MSD) on central hemodynamics and microcirculation were studied in 20 patients with arterial hypertension under acute pharmacological test and on the treatment week 2, 6 and 8. Two variants of hemodynamic response were registered: hypokinetic and hyperkinetic. Unidirectional hemodynamic changes occurred both in short- and long-term therapy. This allows to use the short course for differential choice of patients for cosaar therapy. The best effect of cosaar is expected in patients with a hyperkinetic variant of the hemodynamic response under the short treatment course.
Eliseeva
L N
LN
Blednova
A Iu
AIu
Avakimian
Z A
ZA
Tkachenko
A M
AM
Orlova
T A
TA
D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage*; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D019808:Losartan / Q000008:administration & dosage*; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D016896:Treatment Outcome
D000959:Antihypertensive Agents; D019808:Losartan