In the presence of other inherited or acquired high-risk situations, the FV Cambridge mutation may be an additional thrombophilic risk factor, through its effect on APC sensitivity.
Santacroce
R
R
Bossone
A
A
Brancaccio
V
V
Fortina
P
P
Margaglione
M
M
D020016:Activated Protein C Resistance / Q000209:etiology / Q000235:genetics*; D000328:Adult; D005165:Factor V / Q000235:genetics*; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020125:Mutation, Missense; D010375:Pedigree; D012307:Risk Factors; D019851:Thrombophilia / Q000209:etiology / Q000235:genetics*; D020246:Venous Thrombosis / Q000209:etiology / Q000235:genetics
C119012:factor V Cambridge; D005165:Factor V