[Nuclei with protrusions--"tailed" nuclei--and radiation cytogenetic markers in a lymphocyte culture after x-ray irradiation].
Frequency of the appearance of binuclear cells with nuclei having outgrowth into the cytoplasmic space and arise after first mitosis in human lymphocyte culture is linear-square dependent on the X-irradiation at doses from 0.0 to 4.0 Gy. Positive correlation between frequency of cells with "tailed" nuclei and frequency of metaphases of first mitosis having dicentrics and rings was established. Apparently, formation such "tailed" nuclei is connected with dicentrics and rings.
Nikiforov
A M
AM
All-Russian Centre of Emergency and Radiation Medicine, Emercom of Russia, St. Petersburg. medicine@arcem.spb.ru
Fedortseva
R F
RF
Monosova
E K
EK
Iartseva
N M
NM
Kravtsov
V Iu
VIu
D000328:Adult; D002467:Cell Nucleus / Q000528:radiation effects* / Q000648:ultrastructure; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005819:Genetic Markers / Q000528:radiation effects; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects* / Q000648:ultrastructure; D008677:Metaphase / Q000528:radiation effects; D008938:Mitosis / Q000528:radiation effects
D005819:Genetic Markers