title: Specificity of radioprotective and cytotoxic effects of cysteamine in HeLa S3 cells: generation of peroxide as the mechanism of paradoxical toxicity.
authors.forename: Y
authors.initials: Y
authors.lastname: Takagi
authors.forename: M
authors.initials: M
authors.lastname: Shikita
authors.forename: T
authors.initials: T
authors.lastname: Terasima
authors.forename: S
authors.initials: S
authors.lastname: Akaboshi
mesh_terms: D002374:Catalase / Q000494:pharmacology; D003543:Cysteamine / Q000494:pharmacology* / Q000633:toxicity; D019856:Ethanolamine / Q000494:pharmacology; D005021:Ethylamines / Q000494:pharmacology; D006146:Guanidines / Q000494:pharmacology; D006367:HeLa Cells / Q000187:drug effects* / Q000528:radiation effects; D006735:Horseradish Peroxidase / Q000494:pharmacology; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism; D011837:Radiation-Protective Agents / Q000494:pharmacology* / Q000633:toxicity; D013438:Sulfhydryl Compounds / Q000494:pharmacology; D013482:Superoxide Dismutase / Q000494:pharmacology
chemical_list: D005021:Ethylamines; D006146:Guanidines; D011837:Radiation-Protective Agents; D013438:Sulfhydryl Compounds; D019856:Ethanolamine; D003543:Cysteamine; D006861:Hydrogen Peroxide; D006735:Horseradish Peroxidase; D002374:Catalase; D013482:Superoxide Dismutase; C007638:ethanethiol; C100078:2-mercaptoethylguanidine; C041564:ethylamine