DNA vaccines: a key for inducing long-term cellular immunity.
Over the past few years, major advances in several areas of immunology have provided a foundation for the rational design of vaccines against diseases requiring cellular immunity. Among these advances are the cellular mechanisms by which DNA vaccines can sustain long-term humoral and cellular immunity.
Gurunathan
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Clinical Immunology Section, Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Wu
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Freidag
B L
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Seder
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RA
D000818:Animals; D017951:Antigen Presentation / Q000276:immunology; D005822:Genetic Vectors; D006801:Humans; D007111:Immunity, Cellular; D018320:Leishmania major / Q000276:immunology; D016773:Leishmaniasis, Cutaneous / Q000276:immunology / Q000517:prevention & control; D008288:Malaria / Q000276:immunology / Q000517:prevention & control; D010957:Plasmids; D018417:Th1 Cells / Q000276:immunology*; D013997:Time Factors; D014376:Tuberculosis / Q000276:immunology / Q000517:prevention & control; D019444:Vaccines, DNA / Q000276:immunology*
D019444:Vaccines, DNA