Three cases of pityriasis rubra pilaris successfully treated with cyclosporin A.
BACKGROUND
Pityriasis rubra pilaris (PRP) is reported to respond poorly to cyclosporin A (CsA).


OBJECTIVE
We attempted to determine the efficacy of CsA in the treatment of classic adult-type PRP.


METHODS
Three patients with classic adult-type PRP were treated with 5 mg/kg/day CsA.


RESULTS
A sustained clinical response was achieved within 2-4 weeks of therapy. Relapses were noted when the CsA dose was decreased to 1.2 mg/kg/day.


CONCLUSIONS
CsA should be considered in the treatment of classical adult-type PRP.
Usuki
K
K
Department of Dermatology, Kagoshima University Faculty of Medicine, Japan.
Sekiyama
M
M
Shimada
T
T
Shimada
S
S
Kanzaki
T
T
D000328:Adult; D000368:Aged; D016572:Cyclosporine / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010916:Pityriasis Rubra Pilaris / Q000188:drug therapy* / Q000473:pathology; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D016896:Treatment Outcome
D003879:Dermatologic Agents; D016572:Cyclosporine