Synthesis and antioxidant activity of flavanoid derivatives containing a 1,4-benzodioxane moiety.
Flavanoids bearing a 1,4-benzodioxane moiety [rac-15a, -16a, -17, -18, (-)-15a, (-)-16a] were prepared from protocatechualdehyde (5) and tested for inhibitory activity on the superoxide anion (O2.-) release by human polymorphonuclear leukocytes (PMNLs).
Czompa
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A
Department of Organic Chemistry, University of Debrecen, Hungary.
Dinya
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Z
Antus
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S
Varga
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Z
D000975:Antioxidants / Q000138:chemical synthesis* / Q000494:pharmacology; D005419:Flavonoids / Q000138:chemical synthesis* / Q000494:pharmacology; D006801:Humans; D009504:Neutrophils / Q000378:metabolism; D013329:Structure-Activity Relationship; D013481:Superoxides / Q000378:metabolism
D000975:Antioxidants; D005419:Flavonoids; D013481:Superoxides