title: A regioselective Ru-catalyzed alkene-alkyne coupling.
abstract: [reaction: see text] The reaction of silylalkynes and terminal alkenes proceeds with complete control of regioselectivity by the silyl substituent to give geometrically defined vinylsilanes. Since terminal alkynes normally give mixtures, protodesilylation of these adducts then constitutes a regioselective addition of terminal alkynes to terminal alkenes.
authors.affiliation: Department of Chemistry, Stanford University, CA 94305-5080, USA. bmtrost@leland.stanford.edu
authors.forename: B M
authors.initials: BM
authors.lastname: Trost
authors.forename: M
authors.initials: M
authors.lastname: Machacek
authors.forename: M J
authors.initials: MJ
authors.lastname: Schnaderbeck
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D012428:Ruthenium / Q000737:chemistry*; D012821:Silanes / Q000138:chemical synthesis / Q000737:chemistry*; D014753:Vinyl Compounds / Q000138:chemical synthesis
chemical_list: D000475:Alkenes; D000480:Alkynes; D012821:Silanes; D014753:Vinyl Compounds; D012428:Ruthenium