Determination of mercapturic acids in urine by solid-phase extraction followed by liquid chromatography-electrospray ionization mass spectrometry.
A novel method for the determination of five kinds of mercapturic acids, found in urine as metabolites of alkylbenzenes, based on liquid chromatography-electrospray ionization mass spectrometry is described. A solid-phase extraction procedure was used for the extraction of the mercapturic acids from urine and the separation was performed on a reversed-phase C30 column. The detection limits were in the range 2.4-3.2 ng ml-1.
Moriwaki
H
H
Osaka City Institute of Public Health and Environmental Sciences, Japan.
Tsujimoto
Y
Y
Noda
T
T
Shimizu
M
M
Tanaka
M
M
D000111:Acetylcysteine / Q000652:urine*; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods
D000111:Acetylcysteine