A community pseudo-outbreak of invasive Staphylococcus aureus infection.
Outbreaks of invasive infection caused by methicillin-susceptible and methicillin-resistant Staphylococcus aureus occur in hospitals, long term care institutions, and in patients discharged from these settings. In contrast, epidemic S. aureus infection has not been reported in well persons in the community. Here, we describe a group of healthy young adults who resided in the same neighborhood and participated together in school sports, and who developed serious S. aureus infections within 3 weeks of each other, suggesting a true community outbreak. Timely use of molecular epidemiological tools, however, demonstrated that their illnesses were caused by unrelated bacterial strains.
Adderson
E
E
Department of Pediatrics, University of Utah School of Medicine, and Associated Regional University Pathologists, Salt Lake City, UT, USA.
Pavia
A
A
Christenson
J
J
Davis
R
R
Leonard
R
R
Carroll
K
K
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002437:Cefazolin / Q000494:pharmacology / Q000627:therapeutic use; D002981:Clindamycin / Q000494:pharmacology; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000382:microbiology; D004269:DNA, Bacterial / Q000032:analysis; D004196:Disease Outbreaks; D004917:Erythromycin / Q000494:pharmacology; D005839:Gentamicins / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D008297:Male; D016106:Methicillin Resistance; D009254:Nafcillin / Q000494:pharmacology / Q000627:therapeutic use; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D005839:Gentamicins; D002981:Clindamycin; D009254:Nafcillin; D004917:Erythromycin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D002437:Cefazolin