The suppression of lipoprotein lipase expression in J774.2 macrophages by IFN-gamma and TNF-alpha is mediated at the transcriptional level.
Muhammad
T S
TS
School of Molecular and Medical Biosciences, University of Wales, Cardiff, UK.
Hughes
T R
TR
Cryer
A
A
Ramji
D P
DP
D002460:Cell Line; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects*; D007371:Interferon-gamma / Q000494:pharmacology*; D008071:Lipoprotein Lipase / Q000235:genetics* / Q000378:metabolism; D008264:Macrophages / Q000187:drug effects* / Q000201:enzymology; D012333:RNA, Messenger / Q000235:genetics; D014158:Transcription, Genetic / Q000187:drug effects*; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology*
D012333:RNA, Messenger; D014409:Tumor Necrosis Factor-alpha; D007371:Interferon-gamma; D008071:Lipoprotein Lipase