title: A novel three-component one-pot pyrimidine synthesis based upon a coupling-isomerization sequence.
abstract: [reaction: see text] 2,4,6-Tri(hetero)aryl-substituted pyrimidines can be readily synthesized in a three-component one-pot process based upon a coupling-isomerization sequence of an electron-poor (hetero)aryl halide and a terminal propargyl alcohol subsequently followed by a cyclocondensation with amidinium salts.
authors.affiliation: Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13 (Haus F), D-81377 München, Germany.
authors.forename: T J
authors.initials: TJ
authors.lastname: Müller
authors.forename: R
authors.initials: R
authors.lastname: Braun
authors.forename: M
authors.initials: M
authors.lastname: Ansorge
mesh_terms: D001671:Biochemistry / Q000379:methods*; D011743:Pyrimidines / Q000138:chemical synthesis*
chemical_list: D011743:Pyrimidines