title: Effect of soy milk and bifidobacterium-fermented soy milk on plasma and liver lipids in ovariectomized Syrian hamsters.
abstract: The effects of soy milk and fermented soy milk on lipid metabolism were studied in ovariectomized Syrian hamsters. Five mo-old Syrian hamsters were randomly assigned to four treatment groups: ovariectomized (OVX)+control diet (OVX-C); OVX+soy milk diet (OVX-SM); OVX+fermented soy milk diet (OVX-FSM); and sham-operated+control diet (Sham-C). The hamsters were fed on these diets for 4 wk. The atherogenic index value of the OVX-FSM group was lower than that of the OVX-C group. The plasma triglyceride level of the OVX-FSM group was significantly lower than that of the OVX-C group. The liver total cholesterol contents in the OVX-SM and OVX-FSM groups were significantly lower than that in the OVX-C group. Thus, these results demonstrate that bifidobacterium-fermented soy milk had a hypolipidemic effect in ovariectomized hamsters.
authors.affiliation: Yakult Central Institute for Microbiological Research, Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kikuchi-Hayakawa
authors.forename: N
authors.initials: N
authors.lastname: Onodera-Masuoka
authors.forename: M
authors.initials: M
authors.lastname: Kano
authors.forename: S
authors.initials: S
authors.lastname: Matsubara
authors.forename: E
authors.initials: E
authors.lastname: Yasuda
authors.forename: F
authors.initials: F
authors.lastname: Ishikawa
mesh_terms: D000818:Animals; D001644:Bifidobacterium / Q000378:metabolism*; D006224:Cricetinae; D004036:Diet, Atherogenic; D005260:Female; D005285:Fermentation; D019833:Genistein; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism; D008647:Mesocricetus; D010052:Ovariectomy; D008517:Phytotherapy; D013025:Glycine max / Q000378:metabolism* / Q000627:therapeutic use
chemical_list: D019833:Genistein