All-trans-retinoic acid-induced scrotal ulcerations in a patient with acute promyelocytic leukemia.
Induction therapy with all-trans -retinoic acid has been shown to improve the outcome of patients with acute promyelocytic leukemia, although some side effects occur. Dry skin and lips are among the most common cutaneous side effects. We report a case of scrotal ulcerations induced by all-trans -retinoic acid in an American patient; to our knowledge this is the first such case reported.
Esser
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AC
Department of Dermatology, Mount Sinai School of Medicine, New York, NY 10029, USA. essera01@doc.mssm.edu
Nossa
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Shoji
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Sapadin
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AN
D000970:Antineoplastic Agents / Q000009:adverse effects*; D005832:Genital Diseases, Male / Q000139:chemically induced; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012611:Scrotum; D014212:Tretinoin / Q000009:adverse effects*; D014456:Ulcer / Q000139:chemically induced*
D000970:Antineoplastic Agents; D014212:Tretinoin