title: Uterine perforation with Lippes loop intrauterine device-associated actinomycosis: a case report and review of the literature.
abstract: A case of a 67-year-old postmenopausal woman, gravida 2, para 2, with an uterine perforation from actinomycotic infection with Lippes loop IUD is reported. She had the Lippes loop IUD inserted for 35 years, and had never had any pelvic examination nor Papanicolaou smear. She presented with acute abdominal pain. The clinical picture mimicked peptic ulcer perforation. The woman underwent laparotomy and exudative fluid was discovered in the abdominal cavity with the tip of the Lippes loop IUD at one of the two small holes of the uterine fundus. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. The postoperative microscopic pathological report demonstrated characteristics of actinomycosis. She was treated with parenteral high-dose penicillin for 4 weeks followed by oral penicillin for 6 months. The woman had an uneventful recovery. To our knowledge, this is the first case report of uterine perforation due to Lippes loop IUD-associated actinomycotic infection.
authors.affiliation: Department of Obstetrics & Gynecology, Faculty of Medicine, Chulalongkorn University, Rama IV Road, 10330, Pathumwan, Bangkok, Thailand.
authors.forename: V
authors.initials: V
authors.lastname: Phupong
authors.forename: T
authors.initials: T
authors.lastname: Sueblinvong
authors.forename: K
authors.initials: K
authors.lastname: Pruksananonda
authors.forename: S
authors.initials: S
authors.lastname: Taneepanichskul
authors.forename: S
authors.initials: S
authors.lastname: Triratanachat
mesh_terms: D015746:Abdominal Pain; D000196:Actinomycosis / Q000188:drug therapy / Q000209:etiology*; D000368:Aged; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007434:Intrauterine Devices / Q000009:adverse effects*; D010052:Ovariectomy; D010406:Penicillins / Q000627:therapeutic use; D014595:Uterine Perforation / Q000209:etiology* / Q000382:microbiology / Q000601:surgery
chemical_list: D010406:Penicillins