title: A model for non-specific toxicity with aquatic organisms over relatively long periods of exposure time.
abstract: Experimental data have shown that the internal lethal concentrations of halobenzenes for aquatic organisms decreased with exposure time. In this paper, a model based on the concept of life expectancy reduction was developed to describe this relationship. The model was verified with experimental data for fish (Gambusia affinis) and juvenile crab (Porturius pelagicus(L)). It is proposed that long term non-specific toxicity can be measured as the reduction of the life expectancy of the exposed organism per unit internal concentration (or volume fraction) of the toxic compound. The model can be used to estimate internal lethal concentration at any given exposure period and vice versa. The model can also be used to estimate chronic values of the internal concentration, of the toxicants. It provides a useful tool for assessment of environmental risk of organic compounds in aquatic ecosystems.
authors.affiliation: Faculty of Environmental Sciences, Griffith University Brisbane, Queensland, Australia.
authors.forename: Q
authors.initials: Q
authors.lastname: Yu
authors.forename: Y
authors.initials: Y
authors.lastname: Chaisuksant
authors.forename: D
authors.initials: D
authors.lastname: Connell
mesh_terms: D000465:Algorithms; D000818:Animals; D001555:Benzene Derivatives / Q000633:toxicity*; D003386:Brachyura / Q000502:physiology*; D003532:Cyprinodontiformes / Q000502:physiology*; D004784:Environmental Monitoring; D007928:Lethal Dose 50; D008017:Life Expectancy; D008954:Models, Biological; D013997:Time Factors; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D001555:Benzene Derivatives; D014874:Water Pollutants, Chemical