title: Recovery from chronic hepatitis C in long-term responders to ribavirin plus interferon alfa.
abstract: In 45 sustained responders to interferon alfa and ribavirin, we found long-lasting elimination of hepatitis C virus RNA from serum and liver, together with histopathological improvement, suggesting complete recovery from chronic hepatitis C.
authors.forename: H
authors.initials: H
authors.lastname: Fontaine
authors.forename: M L
authors.initials: ML
authors.lastname: Chaix
authors.forename: J L
authors.initials: JL
authors.lastname: Lagneau
authors.forename: C
authors.initials: C
authors.lastname: Bréchot
authors.forename: S
authors.initials: S
authors.lastname: Pol
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000998:Antiviral Agents / Q000627:therapeutic use*; D001706:Biopsy; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D005260:Female; D016174:Hepacivirus / Q000235:genetics / Q000302:isolation & purification; D006526:Hepatitis C / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D008099:Liver / Q000201:enzymology / Q000473:pathology / Q000821:virology; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011237:Predictive Value of Tests; D012367:RNA, Viral / Q000097:blood; D012254:Ribavirin / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D016898:Interferon-alpha; D012367:RNA, Viral; D012254:Ribavirin; D000410:Alanine Transaminase