title: Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma.
abstract: Kaposi's sarcoma-associated herpesvirus (KSHV) is present in all epidemiologic forms of Kaposi's sarcoma (KS). The KSHV genome contains several open reading frames which are potentially implicated in the development of KS. Some are unique to KSHV; others are homologous to cellular genes. The putative role of these genes in the genesis of KS is discussed.
authors.affiliation: Laboratoire de Virologie Humaine, U412 Inserm, ENS-Lyon, 46 allée d'Italie, 69364 cedex 07, Lyon, France.
authors.forename: H
authors.initials: H
authors.lastname: Gruffat
authors.forename: A
authors.initials: A
authors.lastname: Sergeant
authors.forename: E
authors.initials: E
authors.lastname: Manet
mesh_terms: D002472:Cell Transformation, Viral; D016207:Cytokines / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D016679:Genome, Viral; D019288:Herpesvirus 8, Human / Q000235:genetics* / Q000502:physiology*; D006801:Humans; D012514:Sarcoma, Kaposi / Q000473:pathology / Q000503:physiopathology / Q000821:virology*; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D014779:Virus Replication
chemical_list: D016207:Cytokines; D014764:Viral Proteins