Effectiveness of treatments for nocturnal enuresis in a heterogeneous population.
The objective of this study was to determine the effectiveness of various treatments for nocturnal enuresis in a large, diverse population of children. A retrospective cohort review of patients with nocturnal enuresis was undertaken. All patients selected treatment after a single visit that included a history, examination, and demonstration of treatments. Families were contacted 1 year later to determine what treatment they chose and whether their child still wet. Families primarily chose an alarm (31%), followed by desmopressin acetate (22%) and oxybutynin (9%). Some preferred no treatment (23%). Fifty-six percent of patients using the alarm were completely dry compared to 18% using desmopressin acetate (p<0.0001), 16% using oxybutynin, and 28% receiving no treatment. In a heterogeneous population 1 year after a single visit, children whose parents chose the nocturnal enuresis alarm were most likely to be completely dry.
Schulman
S L
SL
Department of Pediatrics, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, 19104, USA.
Colish
Y
Y
von Zuben
F C
FC
Kodman-Jones
C
C
D000293:Adolescent; D001676:Biofeedback, Psychology / Q000295:instrumentation; D002648:Child; D002675:Child, Preschool; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use*; D004775:Enuresis / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008333:Mandelic Acids / Q000627:therapeutic use*; D010276:Parasympatholytics / Q000627:therapeutic use*; D012076:Renal Agents / Q000627:therapeutic use*; D012189:Retrospective Studies; D016896:Treatment Outcome
D008333:Mandelic Acids; D010276:Parasympatholytics; D012076:Renal Agents; D003894:Deamino Arginine Vasopressin; C005419:oxybutynin