title: Current concepts in intervertebral disc restoration.
abstract: A current focus of treatment for degenerative disk disease is the restoration of the intervertebral disk. This article summarizes the structure and function of the intervertebral disk, the pathogenesis of its degeneration, and the clinical relevance of degenerative disk disease. Current literature relating to intervertebral disk replacement and regeneration is reviewed.
authors.affiliation: Spine Service, Hospital for Special Surgery, New York, New York 10021, USA.
authors.forename: A D
authors.initials: AD
authors.lastname: Diwan
authors.forename: H K
authors.initials: HK
authors.lastname: Parvataneni
authors.forename: S N
authors.initials: SN
authors.lastname: Khan
authors.forename: H S
authors.initials: HS
authors.lastname: Sandhu
authors.forename: F P
authors.initials: FP
authors.lastname: Girardi
authors.forename: F P
authors.initials: FP
authors.lastname: Cammisa
mesh_terms: D000818:Animals; D046508:Culture Techniques; D015316:Genetic Therapy; D006133:Growth Substances / Q000502:physiology; D006801:Humans; D007403:Intervertebral Disc / Q000503:physiopathology / Q000601:surgery*; D012038:Regeneration / Q000502:physiology*; D013122:Spinal Diseases / Q000503:physiopathology / Q000601:surgery*; D019737:Transplants
chemical_list: D006133:Growth Substances