Differences in survivability among F344 rats.
Important parameters to identify and develop appropriate animal models for longevity science include survivability, age-related disorders, and easy handling of aged individuals. It is found that F334/Du and F344/N have distinctive strain difference in these parameters. The finding suggests F334/Du and F344/N, even though they are historically siblings, need clearly separate identification when used as animal models for aging science, in particular, longevity science.
Tanaka
S
S
Laboratory Animal Research Facilities (LARF), National Institute for Longevity Sciences (NILS), Obu, Japan.
Tamaya
N
N
Matsuzawa
K
K
Miyaishi
O
O
D000375:Aging / Q000502:physiology*; D000818:Animals; D005260:Female; D008297:Male; D051381:Rats; D011916:Rats, Inbred F344 / Q000502:physiology*; D013045:Species Specificity; D015996:Survival Rate