Mesial temporal sclerosis and temporal lobe epilepsy: MR imaging deformation-based segmentation of the hippocampus in five patients.
In five patients with mesial temporal sclerosis, the authors verified the precision and reproducibility of hippocampal segmentations with deformation-based magnetic resonance (MR) imaging. The overall percentage overlap between automated segmentations was 92.8% (SD, 3.5%), between manual segmentations was 73.1% (SD, 9.5%), and between automated and manual segmentations was 74.8% (SD, 10.3%). Deformation-based hippocampal segmentations provided a precise method of hippocampal volume measurement in this patient population.
Hogan
R E
RE
Department of Neurology, Saint Louis University, 3635 Vista Ave, St Louis, MO 63110, USA. hoganr2@slu.edu
Mark
K E
KE
Wang
L
L
Joshi
S
S
Miller
M I
MI
Bucholz
R D
RD
D000328:Adult; D004833:Epilepsy, Temporal Lobe / Q000473:pathology*; D005260:Female; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D012598:Sclerosis; D013702:Temporal Lobe / Q000473:pathology*