[Hereditary diseases in pathologoanatomy practice].
This paper is a review of pathological aspects of hereditary diseases. High significance of mutations in lethal effects of human reproduction is shown, especially in miscarriages and infant death. The importance of genetic approaches for the pathologist's practice is emphasized. Current pathology diagnosis of hereditary diseases includes autopsy, biopsy, histological, histochemical, electron microscopic, cytogenetic, molecular genetic tests. Geneticists and pathologists should work together in the directions: analysis of clinical mistakes, study of pathogenesis, etiopathogenic nosology of the diseases, development of new diagnostic methods.
Bochkov
N P
NP
I. M. Sechenov Moscow Medical Academy, Moscow.
D030342:Genetic Diseases, Inborn / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics / Q000473:pathology*; D006801:Humans; D010338:Pathology, Clinical