Cloning, mapping and expression analysis of VPS33B, the human orthologue of rat Vps33b.
We have identified VPS33B, the human ortholog of rat Vps33b. VPS33B encodes a transcript of 2482 nt with an ORF of 617 amino acids and a predicted protein size of 70.6 kDa. VPS33B contains a Sec-1 domain shared with a family of proteins involved in protein sorting and vesicular trafficking. Enriched expression of VPS33B was observed in testis. VPS33B was positioned at chromosome 15q26.1 by radiation hybrid mapping.
Carim
L
L
Medical and Molecular Genetics Center, Institut de Recerca Oncològica, Hospital Duran i Reynals, L'Hospitalet de Llobregat, Barcelona, Spain.
Sumoy
L
L
Andreu
N
N
Estivill
X
X
Escarceller
M
M
D000595:Amino Acid Sequence; D000818:Animals; D002874:Chromosome Mapping; D002884:Chromosomes, Human, Pair 15 / Q000235:genetics*; D003001:Cloning, Molecular; D020224:Expressed Sequence Tags; D020869:Gene Expression Profiling; D006801:Humans; D006822:Hybrid Cells; D008126:Lod Score; D008297:Male; D008565:Membrane Proteins; D008969:Molecular Sequence Data; D016366:Open Reading Frames / Q000235:genetics; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry / Q000235:genetics*; D012333:RNA, Messenger / Q000032:analysis / Q000235:genetics; D051381:Rats; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D016324:Sequence Tagged Sites; D013737:Testis / Q000378:metabolism; D033921:Vesicular Transport Proteins
D008565:Membrane Proteins; D011506:Proteins; D012333:RNA, Messenger; C411584:VPS33B protein, human; D033921:Vesicular Transport Proteins