title: The molecular genetics of cultivated mushrooms.
abstract: The types, economic significance and methods of production of the principal cultivated mushrooms are described in outline. These organisms are all less than ideal for conventional genetic analysis and breeding, so molecular methods afford a particular opportunity to advance our understanding of their biology and potentially give the prospect of improvement by gene manipulation. The sequences described are limited to those found in GenBank by August 1999. The gene sequences isolated from the white button mushroom Agaricus bisporus, the shiitake Lentinula edodes, the oyster mushrooms Pleurotus spp., the paddy straw mushroom Volvariella volvacea and the enotake Flammulina velutipes are described. The largest group are genes from A. bisporus, which includes 29 for intracellular proteins and 12 for secreted proteins. In comparison, only a total of 26 sequences can be reported for the other cultivated species. A. bisporus is also the only cultivated species for which molecular karyotyping is already supported by reliable markers for all 13 of its chromosomes.
authors.affiliation: Division of Life Sciences, King's College London, UK.
authors.forename: J R
authors.initials: JR
authors.lastname: Whiteford
authors.forename: C F
authors.initials: CF
authors.lastname: Thurston
mesh_terms: D000363:Agaricales / Q000201:enzymology / Q000235:genetics*; D001709:Biotechnology / Q000379:methods; D018556:Crops, Agricultural / Q000235:genetics*; D005656:Fungal Proteins / Q000378:metabolism; D005800:Genes, Fungal; D008967:Molecular Biology
chemical_list: D005656:Fungal Proteins