A simple therapeutic combination for type 2 diabetes.
When oral agents alone can no longer provide adequate glycemic control, the combination of a single bedtime injection of insulin with two daily doses of metformin will often normalize blood glucoses levels without the weight gain and hypoglycemia that may occur with other combined regimens.
Department of Medicine, University of Helsinki, Finland.
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Yki-Järvinen
D000284:Administration, Oral; D001786:Blood Glucose / Q000032:analysis; D015190:Blood Glucose Self-Monitoring; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy*; D003927:Diet, Diabetic; D004359:Drug Therapy, Combination; D005215:Fasting / Q000097:blood; D006442:Glycated Hemoglobin / Q000187:drug effects; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000008:administration & dosage; D007267:Injections; D007328:Insulin / Q000008:administration & dosage; D008687:Metformin / Q000008:administration & dosage; D010353:Patient Education as Topic; D015430:Weight Gain / Q000187:drug effects
D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin; D008687:Metformin