A case of segmental myoclonus in amputation stump: evidence for spinal generator and physiopathogenetic hypothesis.
We describe a 68-year-old woman who experienced pain and phantom limb sensation following an above-the-knee amputation of the right leg. A month later, the patient had myoclonic jerks of the stump. Polymyo-graphic recordings showed synchronous jerks in the vastus medialis and adductors of the thigh on the right side. The patient responded to clonazepam. We conclude that the myoclonic jerks were of spinal cord origin.
Ospedale S. Maria del Prato,Department of Neurology and Clinical Neurophysiology, Feltre, Italy.
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Devetag Chalaupka
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Bernardi
D000368:Aged; D000671:Amputation, Surgical; D000927:Anticonvulsants / Q000008:administration & dosage; D002998:Clonazepam / Q000008:administration & dosage; D004576:Electromyography; D005260:Female; D006801:Humans; D009207:Myoclonus / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D010591:Phantom Limb / Q000175:diagnosis / Q000503:physiopathology*; D013116:Spinal Cord / Q000503:physiopathology*
D000927:Anticonvulsants; D002998:Clonazepam