Comparison between two different propofol dosage regimens for insertion of cuffed oro-pharyngeal airway.
Conditions for insertion of the cuffed oropharyngeal airway (COPA) were assessed following two different dosage regimens of propofol: group I (n = 40): 1.5 mg.kg-1; group II (n = 40): 2.5 mg.kg-1. The insertion conditions were evaluated by using a scoring system (-, + and +2) of gag and cough reflexes. The necessary use of additional dosage of propofol and the duration of post-induction apnea were also recorded. There were no significant differences between the two groups in the incidence of coughing, gagging and the additional usage of induction agent. The mean (+/- SD) duration of apnea was significantly longer in the high dose group: 9 +/- 6 min vs 5 +/- 7 min (p = 0.007). Low dose of propofol combines efficient insertion conditions with decreased length of post-induction apnea.
Department of Anesthesiology, Sotiria Hospital, Athens, Greece.
G S
GS
Voyagis
V
V
Dimitriou
G
G
Kostantopoulou
N
N
Charissi
D000328:Adult; D000368:Aged; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D001049:Apnea / Q000139:chemically induced / Q000517:prevention & control; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal; D008297:Male; D008875:Middle Aged; D011229:Preanesthetic Medication; D015742:Propofol / Q000008:administration & dosage
D018686:Anesthetics, Intravenous; D015742:Propofol