[The possibility of using the data on the content of volatile fatty acids for the indirect demonstration of the causative agents of suppurative-inflammatory diseases in the pathological material].
The use of the quantitative content of volatile fatty acids as marker for the indication of the causative agents of pyo-inflammatory diseases in material taken from wounds is proposed. Thus, in 71% of cases the detection of acetic acid in a purulent wound coincided with the bacteriological isolation of monocultures, as well as associations, of facultative anaerobic bacteria. The analysis of isobutyric, butyric, isovaleric, valeric and acetic acids permitted the rapid detection of associations of obligate and facultative anaerobic bacteria in an individual patient. Changes in the quantitative content of volatile fatty acids in pathological material integrally reflected the dynamics of the causative agents of purulent infections and the effectiveness of the prescribed therapy.
State Medical Academy, Ivanovo, Russia.
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Akaĭzin
D000208:Acute Disease; D001419:Bacteria / Q000737:chemistry*; D015415:Biomarkers / Q000032:analysis; D002849:Chromatography, Gas; D002908:Chronic Disease; D005232:Fatty Acids, Volatile / Q000032:analysis*; D006801:Humans; D010019:Osteomyelitis / Q000382:microbiology*; D014946:Wound Infection / Q000382:microbiology*
D015415:Biomarkers; D005232:Fatty Acids, Volatile