[Genetic background of retinoblastoma].
Retinoblastoma is a malignant tumour of the eye ball, which develops as a result of the mutation of both alleles of RB-1 gene. Molecular mechanisms and their implications in clinical diagnosis and genetic counselling in retinoblastoma families are discussed.
Zakład Genetyki Medycznej Polsko-Amerykańskiego Instytutu Pediatrii Collegium Medicum Uniwersytetu Jagiellońskiego.
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Pietrzyk
D005817:Genetic Counseling; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009154:Mutation; D019572:Retinal Neoplasms / Q000175:diagnosis / Q000235:genetics*; D012175:Retinoblastoma / Q000175:diagnosis / Q000235:genetics*; D016160:Retinoblastoma Protein / Q000235:genetics*
D016160:Retinoblastoma Protein