Retinopathy following measles, mumps, and rubella vaccination in an immuno-incompetent girl.
We describe a 4-year-old girl with subnormal visual acuity due to a bilateral retinopathy. The child had a history of encephalitis following MMR vaccination. Temporary retinopathy associated with measles, mumps, and rubella (MMR) vaccination has been described. Recently an idiopathic CD4+ T lymphocytopenia in the child was diagnosed. This cellular immunodeficiency supports our hypothesis of measles retinopathy after vaccination of an immuno-deficient child.
Bartiméus Institute of Visually Impaired Children, Zeist, The Netherlands.
J
J
Schuil
E M
EM
van de Putte
C M
CM
Zwaan
F D
FD
Koole
F M
FM
Meire
D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D008457:Measles / Q000517:prevention & control; D008458:Measles Vaccine / Q000009:adverse effects*; D022542:Measles-Mumps-Rubella Vaccine; D009107:Mumps / Q000517:prevention & control; D009108:Mumps Vaccine / Q000009:adverse effects*; D012164:Retinal Diseases / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis / Q000276:immunology; D012409:Rubella / Q000517:prevention & control; D012411:Rubella Vaccine / Q000009:adverse effects*; D018344:T-Lymphocytopenia, Idiopathic CD4-Positive / Q000150:complications* / Q000276:immunology; D017778:Vaccines, Combined / Q000009:adverse effects; D014792:Visual Acuity
D007074:Immunoglobulin G; D008458:Measles Vaccine; D022542:Measles-Mumps-Rubella Vaccine; D009108:Mumps Vaccine; D012411:Rubella Vaccine; D017778:Vaccines, Combined