[Ischemic colitis as a primary manifestation of an embolizing small-cell bronchial carcinoma infiltrating a pulmonary vein].
METHODS
A 59-year-old male patient was admitted to hospital for general malaise with muscle and bone pain. Some weeks ago he had been treated with roxithromycin because of pneumonia. Physical examination revealed melena. Hemoglobin was 7.6 g/l. Endoscopy of the upper gastrointestinal tract did not show a bleeding source. Colonoscopy and histologic examination revealed hemorrhage caused by ischemic colitis. To rule out cardiac embolies in the presence of paroxysmal tachyarrhythmia absoluta a transesophageal echocardiogram was performed. A mediastinal mass infiltrating the upper left pulmonary vein was detected. The mass had not been visible on routine chest X-ray. Histologic examination of a bronchoscopically taken specimen revealed an oat-cell bronchial carcinoma.


CONCLUSIONS
In this patient invasion of a pulmonary vein by the bronchial carcinoma lead to embolies which caused mesenterial ischemia. According to our researches this is the first report of ischemic colitis as a manifestation of bronchial carcinoma.
Medizinische Kliniken, Diakonissenkrankenhaus Stuttgart. Woehr@diak-stuttgart.de
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Wöhr
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Mück
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Ziegler
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Heidemann
D001984:Bronchial Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D001999:Bronchoscopy; D018288:Carcinoma, Small Cell / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D017091:Colitis, Ischemic / Q000209:etiology*; D003937:Diagnosis, Differential; D018450:Disease Progression; D017548:Echocardiography, Transesophageal; D004724:Endoscopy; D006801:Humans; D008297:Male; D008642:Mesenteric Veins; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011667:Pulmonary Veins / Q000473:pathology; D013927:Thrombosis / Q000209:etiology; D019043:Vascular Neoplasms / Q000556:secondary*