Synthesis and antifungal activities of 5/6-arylamino-4,7-dioxobenzothiazoles.
5/6-Arylamino-4,7-dioxobenzothiazoles were synthesized and tested for in vitro antifungal activities against pathogenic fungi. Most of the tested 4,7-dioxobenzothiazoles exhibited potent antifungal activities against Candida species and Aspergillus niger.
Ryu
C K
CK
College of Pharmacy, Ewha Womans University, Seoul, South Korea. ckryu@mm.ewha.ac.kr
Kang
H Y
HY
Yi
Y J
YJ
Shin
K H
KH
Lee
B H
BH
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001234:Aspergillus niger / Q000187:drug effects*; D002175:Candida / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D015195:Drug Design; D006801:Humans; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000935:Antifungal Agents; D013844:Thiazoles