Acute left anterior descending artery occlusion in a hemophiliac A patient during recombinant factor VIII infusion: treatment with coronary angioplasty.
Acute myocardial infarction in association with the replacement of recombinant factor VIII in hemophiliacs has not been documented. We describe the use of PTCA in a hemophiliac A patient who developed acute myocardial infarction during factor VIII replacement. Because surgery in hemophiliac A patients remains hazardous, PTCA seems to be an attractive alternative.
Department of Medicine, Easton Hospital, MCP-Hahnemann University, PA, USA. alsolaiman@pol.net
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Alsolaiman
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Chang
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Arjomand
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Oza
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Costacurta
D000328:Adult; D015906:Angioplasty, Balloon, Coronary; D005169:Factor VIII / Q000008:administration & dosage / Q000009:adverse effects*; D006467:Hemophilia A / Q000188:drug therapy*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000628:therapy; D015635:Radionuclide Ventriculography; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000009:adverse effects*
D011994:Recombinant Proteins; C078147:F8 protein, human; D005169:Factor VIII