Familial pyloric atresia: report of a family and review of the literature.
Pyloric atresia occurs in one in a million births and usually occurs sporadically. We report a family with nine affected members and review the literature for all reported familial cases. The article stresses the possibility of recurrence of pyloric atresia in the progeny of consanguinous parents, with an emphasis on prenatal diagnosis and counseling, diagnosis of the entity in neonates, associated conditions, and prognosis in sporadic and familial cases. A high index of suspicion in affected families contributes to the early diagnosis and treatment with a great impact on outcome.
Department of Obstetrics and Gynecology, American University of Beirut, Medical Center, Lebanon. ui00@aub.edu.lb
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D000328:Adult; D002585:Cesarean Section; D005260:Female; D017219:Gastric Outlet Obstruction / Q000235:genetics*; D005774:Gastrostomy; D006801:Humans; D007231:Infant, Newborn; D007409:Intestinal Atresia / Q000235:genetics*; D008297:Male; D006831:Polyhydramnios / Q000150:complications; D011247:Pregnancy; D011708:Pylorus / Q000002:abnormalities*