Synthesis and biological activity of 4'-methoxy derivatives of abscisic acid.
Replacing the 4'-carbonyl group of abscisic acid with a methoxy group does not affect the abscisic acid (ABA)-like activities of the product in barley aleurone protoplasts, although the reduction of ABA to 4'-hydroxyl derivatives significantly reduces the ABA-like activity of the products. This suggests that methoxy derivatives of abscisic acid might be used to produce probes for ABA binding proteins.
Asami
T
T
RIKEN (The Institute of Physical and Chemical Research), Wako, Saitama, Japan. tasami@postman.riken.gp.jp
Min
Y K
YK
Nakano
T
T
Matsuyama
T
T
Murofushi
N
N
Yamaguchi
I
I
Yoshida
S
S
D000040:Abscisic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D015195:Drug Design; D004790:Enzyme Induction / Q000187:drug effects; D001467:Hordeum / Q000201:enzymology; D015394:Molecular Structure; D010937:Plant Growth Regulators / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011523:Protoplasts / Q000187:drug effects / Q000201:enzymology; D013329:Structure-Activity Relationship; D000516:alpha-Amylases / Q000096:biosynthesis*
D010937:Plant Growth Regulators; D000040:Abscisic Acid; D000516:alpha-Amylases