Fluvoxamine strongly inhibits melatonin metabolism in a patient with low-amplitude melatonin profile.
M
M
Grözinger
S
S
Härtter
X
X
Wang
J
J
Röschke
C
C
Hiemke
D M
DM
Rose
D002940:Circadian Rhythm / Q000187:drug effects; D003577:Cytochrome P-450 Enzyme System / Q000187:drug effects / Q000378:metabolism; D004359:Drug Therapy, Combination; D005260:Female; D016666:Fluvoxamine / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000378:metabolism; D008550:Melatonin / Q000097:blood / Q000378:metabolism* / Q000627:therapeutic use*; D008875:Middle Aged; D017367:Selective Serotonin Reuptake Inhibitors / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D012890:Sleep / Q000187:drug effects; D007319:Sleep Initiation and Maintenance Disorders / Q000097:blood / Q000188:drug therapy* / Q000378:metabolism; D016896:Treatment Outcome
D003577:Cytochrome P-450 Enzyme System; D016666:Fluvoxamine; D006854:Hydrocortisone; D008550:Melatonin; D017367:Selective Serotonin Reuptake Inhibitors