Reactivation of varicella-zoster virus in delayed facial palsy after dental treatment and oro-facial surgery.
In rare cases, acute peripheral facial palsy occurs several days after dental treatment and oro-facial surgery. Surgical procedures have been known to trigger reactivation of varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1). The present study examined eight patients who exhibited delayed facial palsy after dental treatment or oro-facial surgery. Ramsay Hunt syndrome was diagnosed in three patients and varicella-zoster virus (VZV) reactivation without zoster lesions (zoster sine herpete) was diagnosed in three patients either by PCR or serological assay. Therefore, VZV reactivation was detected in 75% (6 of 8) of patients who exhibited delayed facial palsy after dental or oro-facial treatment. The results suggest that VZV reactivation is a major cause of delayed facial palsy after dental treatment or oro-facial surgery.
Department of Otolaryngology, Hokkaido University School of Medicine, Sapporo, Japan. yfuruta@med.hokudai.ac.jp
Y
Y
Furuta
F
F
Ohtani
S
S
Fukuda
Y
Y
Inuyama
K
K
Nagashima
D000328:Adult; D000368:Aged; D004279:DNA, Viral / Q000032:analysis; D005158:Facial Paralysis / Q000175:diagnosis* / Q000821:virology; D005260:Female; D016697:Herpes Zoster Oticus / Q000175:diagnosis* / Q000821:virology; D018259:Herpesvirus 1, Human / Q000254:growth & development*; D014645:Herpesvirus 3, Human / Q000254:growth & development*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019647:Oral Surgical Procedures / Q000009:adverse effects*; D016133:Polymerase Chain Reaction; D011183:Postoperative Complications / Q000175:diagnosis* / Q000821:virology; D012463:Saliva / Q000821:virology; D013997:Time Factors; D014076:Tooth Diseases / Q000628:therapy; D014775:Virus Activation; D017735:Virus Latency
D004279:DNA, Viral