Apolipoprotein-E epsilon 4 allele frequency and conferred risk for Cuban Americans with Alzheimer's disease.
The authors compared Apo-E epsilon 4 frequencies for Cuban American and white non-Hispanic persons with and without Alzheimer's disease (AD). The Apo-E epsilon 4 allele conferred as large a risk for AD in Cuban Americans as for white non-Hispanics, a finding that differs from those for Hispanic subjects as a whole.
Department of Psychiatry, University of Miami School of Medicine, FL 33136, USA.
S
S
Sevush
G
G
Peruyera
F
F
Crawford
M
M
Mullan
D000368:Aged; D000483:Alleles; D000544:Alzheimer Disease / Q000208:ethnology* / Q000235:genetics*; D053327:Apolipoprotein E4; D001057:Apolipoproteins E / Q000235:genetics*; D016022:Case-Control Studies; D003462:Cuba / Q000208:ethnology; D005260:Female; D005431:Florida; D005838:Genotype; D006630:Hispanic or Latino / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D044465:White People / Q000235:genetics
D053327:Apolipoprotein E4; D001057:Apolipoproteins E