Fludarabine induced intestinal pseudo-obstruction: case report and literature review.
Intestinal pseudo-obstruction is a recognized but rare complication of chemotherapy. Vinca alkaloids and cytarabine have been reported to be associated with intestinal pseudo-obstruction. We report a case of fludarabine induced severe intestinal pseudo-obstruction in a 66-year-old man suffering from non-Hodgkin's lymphoma, and describe our successful management of this with a combination of parasympathomimetic and mechanical decompression, after failure of conservative management.
The Gastrointestinal Unit, Western General Hospital, Edinburgh, UK.
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S
Campbell
R
R
Thomas
A
A
Parker
S
S
Ghosh
D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy; D008297:Male; D011859:Radiography; D014740:Vidarabine / Q000009:adverse effects* / Q000031:analogs & derivatives* / Q000627:therapeutic use
D000970:Antineoplastic Agents; D014740:Vidarabine; C024352:fludarabine