[Tocopherol Succinate Reference Standard (Control 981) of National Institute of Health Sciences].
The raw material of tocopherol succinate was tested for preparation of the "Tocopherol Succinate Reference Standard (Control 981)". The analytical data obtained were: infrared spectrum same as that of the Tocopherol Succinate Reference Standard (Control 8510); specific absorbance, E(1%)1 cm (286 nm) = 40.7; thin-layer chromatography, no impurities detected until 50.0 microgram; high-performance liquid chromatography (HPLC),three impurities detected and amount of tocopherol succinate estimated to be 98.2%, loss on drying, 0.19%, assay by HPLC, 101.7%. Based on the above results, the raw material was authorized as the Japanese Pharmacopoeia Reference Standard (Control 981).
Maekawa
K
K
Iwata
M
M
Saito
H
H
Tanimoto
T
T
Okada
S
S
D006077:Government Agencies; D007564:Japan; D010602:Pharmacopoeias as Topic / Q000592:standards; D012015:Reference Standards; D024505:Tocopherols; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000592:standards
D014810:Vitamin E; D024505:Tocopherols