Indinavir use: associated reversible hair loss and mood disturbance.
We present the case of a 55-year-old heterosexual man who had a generalized alopecia and mood changes associated with the antiretroviral protease inhibitor; indinavir within 6 months of use. This was reversed within 3 months of change of therapy to the protease inhibitor, nelfinavir with demonstrable changes in his Hospital Anxiety and Depression (HAD) scale scores.
Harry
T C
TC
Department of Genitourinary Medicine, Bure Clinic, James Paget Healthcare NHS Trust, Great Yarmouth, Norfolk, UK. tcharry@bureclinic.com
Matthews
M
M
Salvary
I
I
D000505:Alopecia / Q000139:chemically induced* / Q000628:therapy; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D017320:HIV Protease Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D015497:HIV-1; D006801:Humans; D019469:Indinavir / Q000009:adverse effects* / Q000627:therapeutic use; D007508:Irritable Mood; D008297:Male; D008875:Middle Aged
D017320:HIV Protease Inhibitors; D019469:Indinavir