Hepatocellular carcinoma followed by Waldenström's macroglobulinemia: a case report.
A case of hepatocellular carcinoma associated with Waldenström's macroglobulinemia is reported. During treatment and follow-up of hepatocellular carcinoma, a 54-year-old man was found to have a progressive monoclonal increase in serum IgM level and subsequently was diagnosed as having Waldenström's macroglobulinemia. Chemotherapy was carried out to prevent hyperviscosity syndrome due to Waldenström's macroglobulinemia without any surgical management for hepatocellular carcinoma. The association of these diseases is quite rare; only 6 cases have been reported in the literature, and this is the first case in which hepatocellular carcinoma preceded Waldenström's macroglobulinemia.
Division of Hepatobiliary and Pancreatic Surgery, Faculty of Medicine, University of Tokyo, Japan.
K
K
Hasegawa
K
K
Kubota
H
H
Hirai
Y
Y
Imai
Y
Y
Midorikawa
M
M
Makuuchi
D001809:Blood Viscosity; D006528:Carcinoma, Hepatocellular / Q000150:complications*; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008113:Liver Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D008258:Waldenstrom Macroglobulinemia / Q000097:blood / Q000150:complications* / Q000188:drug therapy
D007075:Immunoglobulin M