Neuropsychological sequelae in Kleine-Levin syndrome: case report.
Kleine-Levin syndrome is characterized by periodic hypersomnia, hyperphagia, sexual disinhibitions and behavioral disturbances. The prognosis is generally benign, with normal cognitive and social functions after the episodes. We describe a typical case of Kleine-Levin syndrome associated with apparent academic decline, neuropsychological sequelae and personality alterations after the second episode of the illness. Further research in the natural history of Kleine-Levin syndrome is needed, for example, to determine whether early intervention would improve long-term prognosis.
Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. lfontenelle@bigfoot.com
L
L
Fontenelle
M V
MV
Mendlowicz
J C
JC
Gillin
P
P
Mattos
M
M
Versiani
D000293:Adolescent; D006801:Humans; D017593:Kleine-Levin Syndrome / Q000503:physiopathology* / Q000523:psychology; D008297:Male; D008418:Masturbation; D009483:Neuropsychological Tests; D010554:Personality Disorders; D011379:Prognosis; D014477:Underachievement