[The relationship between hepatocellular carcinoma and hepatitis C virus infection in Guangxi, China].
OBJECTIVE
To study the significance of HCV infection as a risk factor for hepatocellular carcinoma (HCC) in Guangxi.


METHODS
Monoclonal antibodies against the core, NS3 and NS4 region of HCV, and anti-HBsAg antibody were used for immunohistochemical staining.


RESULTS
The frequency of HCV infection from regions with high, intermediate and low prevalence of HCC was 24/63(38.1%), 23/62 (37.1%) and 30/77(39.0%), respectively, while that of HBsAg was 84.1%, 83.8% and 84.4%, respectively. The overall positive rate of HCV infection was 77/202 (38.1%), and of HBV infection was 170/202 (84.2%).


CONCLUSIONS
While HBV infection frequently accompanies HCC, HCV infection is present in more than 1/3 of HCC. This is generally the case regardless of geographical difference in HCC prevalence.
Guangxi Medical University, Nanning.
Z
Z
Deng
Y
Y
Ma
D
D
Li
D000911:Antibodies, Monoclonal / Q000032:analysis; D006528:Carcinoma, Hepatocellular / Q000821:virology*; D002681:China; D016174:Hepacivirus / Q000302:isolation & purification*; D006526:Hepatitis C; D018937:Hepatitis C Antibodies / Q000032:analysis; D006801:Humans; D008113:Liver Neoplasms / Q000821:virology*
D000911:Antibodies, Monoclonal; D018937:Hepatitis C Antibodies