[Hashimoto encephalopathy: steroid-sensitive encephalopathy in Hashimoto thyroiditis].
Hashimoto's encephalopathy is a steroid-responsive, relapsing or progressive encephalopathy associated with Hashimoto's thyroiditis. Characteristic clinical features are confusion, seizures, alteration in conscious level, stroke-like episodes, myoclonus, and tremulousness. High CSF protein levels without pleocytosis and a diffusely abnormal EEG are typical findings. Brain CT and MRI and cerebral angiogram are usually normal. We present two case reports of Hashimoto's encephalopathy in 55- and 77-year-old patients who both responded well to steroid therapy, and review the literature.
Neurologische Klinik, Zentralklinikum Augsburg.
M
M
Hartmann
B
B
Schaner
K
K
Scheglmann
A
A
Bücking
R
R
Pfister
D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001323:Autoantibodies / Q000097:blood; D001928:Brain Diseases, Metabolic / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D003937:Diagnosis, Differential; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008875:Middle Aged; D013256:Steroids; D013960:Thyroid Function Tests; D013967:Thyroiditis, Autoimmune / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D001323:Autoantibodies; D013256:Steroids