Shifts in membrane fatty acid profiles associated with acid adaptation of Streptococcus mutans.
Cells of Streptococcus mutans UA159 physiologically adapted to acidification during growth at pH 5 in glucose-limited chemostat cultures were enriched in mono-unsaturated and longer chain fatty acids compared with unadapted cells grown under the same conditions but at pH 7. Ratios of unsaturated to saturated fatty acids in the cells were, respectively, 1.2 and 0.3. Cyclopropane fatty acids were not detected. Streptococcus sobrinus 6715, which is known to have minimal acid-adaptive capacity, showed only minimal change in membrane fatty acids.
Center for Oral Biology, University of Rochester, New York 14642, USA. robert_quivey@urmc.rochester.edu
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D000222:Adaptation, Physiological; D002462:Cell Membrane / Q000737:chemistry*; D003470:Culture Media; D005227:Fatty Acids / Q000032:analysis*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D013295:Streptococcus mutans / Q000737:chemistry / Q000254:growth & development*
D003470:Culture Media; D005227:Fatty Acids