Prediction of letter contrast sensitivity using videokeratographic indices.
OBJECTIVE
To analyze the relationship between corneal topography and letter contrast sensitivity.


METHODS
Experiments were conducted on 59 eyes of 51 patients who had best spectacle-corrected visual acuity of 20/20 or better and no ocular pathology except for the corneal shape. Thirty-nine eyes had an abnormal topographic pattern resulting from keratoconus, and the other 20 eyes showed a normal topographic pattern. Videokeratography was performed with the TMS-2 videokeratoscope, and the surface regularity index, surface asymmetry index, and coefficient of variation of power were obtained for each subject. Letter contrast sensitivity was measured with the CSV-1000LV with spectacle correction. The correlation between the number of correct letters and topographic indices was calculated.


RESULTS
The abnormal topography group had a significantly greater loss of letter contrast sensitivity (median = 20 letters) than the normal control (median = 23 letters; P =.0001). There were statistically significant correlations between number of correct letters and the coefficient of variation of power (r = -.77; P =. 001), number of correct letters and surface regularity index (r = -. 76, P =.001), and the number of correct letters and surface asymmetry index (r = -.64; P =.001). The linear regression equation between number of correct letters and the coefficient of variation of power was the number of correct letters = -0.05 x the coefficient of variation of power + 23.2.


CONCLUSIONS
Our results suggest that subtle visual deteriorations, which are barely detected by contrast sensitivity testing, can be predicted objectively by the corneal topographic indices.
Department of Ophthalmology, Osaka University Medical School, Suita, Japan. nmaeda@ophthal.med.osaka-u.ac.jp
N
N
Maeda
S
S
Sato
H
H
Watanabe
Y
Y
Inoue
T
T
Fujikado
Y
Y
Shimomura
Y
Y
Tano
D000328:Adult; D015350:Contrast Sensitivity / Q000502:physiology*; D003315:Cornea / Q000503:physiopathology*; D019781:Corneal Topography; D005139:Eyeglasses; D005260:Female; D006801:Humans; D007640:Keratoconus / Q000503:physiopathology*; D008297:Male; D015351:Vision Screening / Q000295:instrumentation