Unusual complications of warfarin therapy: skin necrosis and priapism.
Skin necrosis and priapism are unusual complications of warfarin therapy. We report a teenager with warfarin-associated skin necrosis and priapism who was subsequently found to be a compound heterozygote for protein C deficiency and a heterozygote for the factor V Leiden mutation.
Zimbelman
J
J
Department of Pediatrics, University of Colorado Health Sciences Center, Aurora, Colorado 80045-0507, USA.
Lefkowitz
J
J
Schaeffer
C
C
Hays
T
T
Manco-Johnson
M
M
Manhalter
C
C
Nuss
R
R
D000293:Adolescent; D000925:Anticoagulants / Q000009:adverse effects*; D003875:Drug Eruptions / Q000150:complications / Q000209:etiology* / Q000473:pathology; D005165:Factor V / Q000235:genetics; D006801:Humans; D008297:Male; D009336:Necrosis; D011317:Priapism / Q000139:chemically induced* / Q000150:complications; D020151:Protein C Deficiency / Q000150:complications; D019851:Thrombophilia / Q000235:genetics; D014859:Warfarin / Q000009:adverse effects*
D000925:Anticoagulants; D014859:Warfarin; D005165:Factor V