Exercise in the heat is limited by a critical internal temperature.
We examined whether fatigue during exertional heat stress occurred at a critical internal temperature independent of the initial temperature at the start of exercise. Microwaves (2.1 GHz; 100 mW/cm(2)) were used to rapidly (3-8 min) heat rats before treadmill exercise to exhaustion. In a repeated-measures design, food-restricted male Sprague-Dawley rats (n = 11) were preheated to three levels (low, medium, and high). In addition, two sham exposures, Sham 1 and Sham 2, were administered at the beginning and end of the study, respectively. At the initiation of exercise, hypothalamic (T(hyp)) and rectal (T(rec)) temperatures ranged from 39.0 degrees C to 42.8 degrees C (T(hyp)) and 42.1 degrees C (T(rec)). The treadmill speed was 17 m/min (8 degrees grade), and the ambient temperature during exercise was 35 degrees C. Each treatment was separated by 3 wk. Run time to exhaustion was significantly reduced after preheating. There was a significant negative correlation between run time and initial T(hyp) and T(rec) (r = 0.73 and 0.74, respectively). The temperatures at exhaustion were not significantly different across treatments, with a range of 41.9-42.2 degrees C (T(hyp)) and 42.2-42.5 degrees C (T(rec)). There were no significant differences in run time in the sham runs administered at the start and end of the investigation. No rats died as a result of exposure to any of the treatments, and body weight the day after each treatment was unaffected. These results support the concept that a critical temperature exists that limits exercise in the heat.
Walters
T J
TJ
Air Force Research Laboratory, Directed Energy Bioeffects Division, Brooks Air Force Base, TX, USA. thomas.walter@cen.amedd.army.mil
Ryan
K L
KL
Tate
L M
LM
Mason
P A
PA
D000818:Animals; D001831:Body Temperature / Q000502:physiology*; D006358:Hot Temperature / Q000009:adverse effects*; D007031:Hypothalamus / Q000502:physiology; D008297:Male; D008872:Microwaves; D005082:Physical Exertion / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012420:Running / Q000502:physiology; D013238:Stereotaxic Techniques; D015431:Weight Loss / Q000502:physiology