Rate of loss of irradiated polyglactin 910 (Vicryl Rapide) from the mouth: a prospective study.
We aimed to find out how long irradiated polyglactin 910 (Vicryl Rapide) remained in the oral tissues and to investigate the effect of chlorhexidine mouthwash on absorption time and bacterial growth on sutures. Twenty-one volunteers each had two Vicryl Rapide sutures placed intraorally under local anaesthesia. Ten of these subjects used chlorhexidine mouthwash twice daily. After 7 days, one suture was removed to be cultured for aerobic and anaerobic bacteria. The other was monitored for time from insertion to loss. The median survival value was 3 days (range 1-13). The median number of days to suture loss was less in the chlorhexidine group (3, range 1-11) than in the control group (4, range 1-13) but this was not significant. There were no significant differences in aerobic and anaerobic counts between the two groups. Vicryl Rapide may be useful for intraoral use.
Restorative Dentistry, Glasgow Dental Hospital and School, Glasgow, UK.
L K
LK
McCaul
J
J
Bagg
W M
WM
Jenkins
D000328:Adult; D002710:Chlorhexidine / Q000494:pharmacology; D015169:Colony Count, Microbial; D005260:Female; D005881:Gingiva / Q000378:metabolism* / Q000382:microbiology; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate / Q000187:drug effects; D008875:Middle Aged; D009067:Mouthwashes / Q000494:pharmacology; D019647:Oral Surgical Procedures / Q000295:instrumentation*; D011098:Polyglactin 910 / Q000378:metabolism* / Q000528:radiation effects*; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D013537:Sutures / Q000382:microbiology*; D016896:Treatment Outcome
D009067:Mouthwashes; D011098:Polyglactin 910; D002710:Chlorhexidine