[Cartography of absolute myocardial perfusion with magnetic resonance imaging. Methods and results].
Ultra-rapid dynamic MRI (one image per heart beat) can follow the progression of the intra-myocardial signal during the first passage of diffusable gadolinium chelates injected as a bolus through a peripheral vein. A quantitative evaluation of myocardial perfusion is possible using a compartmental model of analysis. Absolute myocardial flow can be measured at rest and during hyperaemia induced by dipyridamole. It is possible to associate functional mapping, corresponding to parametric images of the flow indices, to the global evaluation. The ratio between the values obtained during hyperaemia and under basal conditions correspond to the myocardial reserve. The principles, results and limitations of this method are discussed in the light of published results, underlining the advantages of absolute flow measurement and of the differences between the results of MRI and myocardial scintigraphy.
Service de cardiologie, hopital de Hautepierre, Strasbourg.
G
G
Roul
P
P
Germain
P M
PM
Coulbois
A
A
Constantinesco
C
C
Jahn
J L
JL
Dietemann
P
P
Bareiss
D003326:Coronary Circulation; D005682:Gadolinium; D006321:Heart / Q000502:physiology; D006339:Heart Rate; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012039:Regional Blood Flow; D012680:Sensitivity and Specificity
D005682:Gadolinium