[Feasibility study of laser-induced fluorescence (LIF) spectrum for diagnosis of colon cancer].
OBJECTIVE
To study the usefulness of laser-induced fluorescence (LIF) spectrum for diagnosis of colon cancer.


METHODS
Nitrogen laser, wavelength 337 nm, optical multichannel analyzer (OMA III) were used to demonstrate LIF spectra. A standard spectrum of LIF of colon cancer was used to analyse that of 51 surgically removed colon specimens and the results were compared with pathological findings.


RESULTS
Compared with pathological findings, LIF spectrum examination had 80.0% sensitivity, 100% specificity, with positive predictive value of 100%, negative predictive value of 83.9% and accuracy of 90.2% for the diagnosis of colon cancer, respectively.


CONCLUSIONS
Laser-induced fluorescence (LIF) spectrum of colon is of use in the diagnosis of colon cancer.
Department of Gastroenterology, Beijing Army General Hospital.
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L
Zhai
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Li
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Gao
D003110:Colonic Neoplasms / Q000175:diagnosis*; D005240:Feasibility Studies; D006801:Humans; D007834:Lasers; D012680:Sensitivity and Specificity; D013050:Spectrometry, Fluorescence