Unique cellular features in a testicular plasmacytoma.
A case of testicular plasmacytoma is described at the light and fine structure level. The patient was a 54-year-old male with a history of multiple myeloma. The testicular tumor was restricted to an interstitial space growth. Plasma cells varied in differentiation with few obtaining the cartwheel nucleus and prominent Golgi of connective tissue plasma cells. Cytoplasmic inclusions were characteristic of most cells and a large number of intranuclear inclusions were present. To our knowledge, this is the first report of such inclusions in the cells of a testicular plasmacytoma. Their significance in cases of end stage myeloma is discussed.
Department of Anatomy and Cell Biology, Oklahoma State University College of Osteopathic Medicine, Tulsa, USA. meekwd@osu-com.okstate.edu
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D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009101:Multiple Myeloma / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D010950:Plasma Cells / Q000648:ultrastructure; D010954:Plasmacytoma / Q000601:surgery / Q000648:ultrastructure*; D013736:Testicular Neoplasms / Q000601:surgery / Q000648:ultrastructure*