Upregulation of the interleukin-8 system in hypercholesterolemic patients. Does inhibition of the mevalonate pathway lower interleukin-8 levels in the vessel wall?
Sindermann
J R
JR
Schmidt
A
A
Breithardt
G
G
D000911:Antibodies, Monoclonal; D001161:Arteriosclerosis / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control; D015415:Biomarkers; D001808:Blood Vessels / Q000378:metabolism* / Q000473:pathology; D002455:Cell Division; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D006937:Hypercholesterolemia / Q000188:drug therapy / Q000378:metabolism* / Q000473:pathology; D016209:Interleukin-8 / Q000378:metabolism*; D008798:Mevalonic Acid / Q000037:antagonists & inhibitors*; D009131:Muscle, Smooth, Vascular / Q000378:metabolism / Q000473:pathology; D015854:Up-Regulation
D000911:Antibodies, Monoclonal; D015415:Biomarkers; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D016209:Interleukin-8; D008798:Mevalonic Acid