[The action of a preparation of Escherichia coli M-17 growth autostimulants (Actoflor) on the growth of pure and mixed bacterial cultures].
The effect of the preparation of E. coli M-17 low-molecular exometabolites (Actoflor), containing growth autostimulators, on the growth of pure cultures of E. coli M-17 E. coli K-12, Salmonella enteritidis, Serratia marcescens and Bifidobacterium adolescentis MC-42 was studied. This preparation was shown to stimulate the growth of all above-mentioned bacteria. The addition of Actoflor also led to the acceleration of growth in the cultivation of mixed cultures of E. coli M-17 with E. coli K-12 (or S. enteritidis), the producer strain (E. coli M-17) showing the highest degree of acceleration. Moreover, the action of Actoflor led to the elimination of competitor strains and to the increase of the antagonistic activity of E. coli M-17. Actoflor may be supposedly used as a therapeutic or prophylactic remedy.
State Scientific Center--Research Institute of Highly Pure Biopreparations, State Pediatric Medical Academy, St. Petersburg, Russia.
T Ia
TIa
Vakhitov
O Iu
OIu
Iashina
L N
LN
Petrov
A M
AM
Koroliuk
D001644:Bifidobacterium / Q000187:drug effects / Q000254:growth & development; D003470:Culture Media; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development; D006133:Growth Substances / Q000494:pharmacology*; D008970:Molecular Weight; D012477:Salmonella enteritidis / Q000187:drug effects / Q000254:growth & development; D012706:Serratia marcescens / Q000187:drug effects / Q000254:growth & development; D013268:Stimulation, Chemical
D003470:Culture Media; D006133:Growth Substances