Hypoglycemic activity of bio-tea in mice.
Administration of bio-tea (1.71 ml/kg) to normal albino mice caused hypoglycemia after 30 min which reached to maximum after 2 hr with a significant decrease in blood sugar level (BSL) and became normal beyond 8 hr. In alloxan-induced diabetic albino mice, repeated treatments of bio-tea for 3 days (five doses) brought about a significant fall in mean BSL. Continuous decrease in BSL was observed after 4 hr of administration of last dose of bio-tea. Hypoglycemic effect was persistent in alloxan-induced diabetic mice. Effect on glucose tolerance test showed a significant fall in BSL of bio-tea treated animals after 1 hr of glucose treatment indicating hypoglycemic effect of bio-tea.
Department of Biosciences, Mangalore University, Mangalagangotri, India.
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Shenoy
D000091:Acetobacter / Q000737:chemistry; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000178:diet therapy; D007004:Hypoglycemic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D051379:Mice; D012440:Saccharomyces / Q000737:chemistry; D013559:Symbiosis; D013662:Tea / Q000737:chemistry* / Q000382:microbiology
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D013662:Tea