Indinavir use: associated reversible hair loss and mood disturbance.
We present the case of a 55-year-old heterosexual man who had a generalized alopecia and mood changes associated with the antiretroviral protease inhibitor; indinavir within 6 months of use. This was reversed within 3 months of change of therapy to the protease inhibitor, nelfinavir with demonstrable changes in his Hospital Anxiety and Depression (HAD) scale scores.
Department of Genitourinary Medicine, Bure Clinic, James Paget Healthcare NHS Trust, Great Yarmouth, Norfolk, UK. tcharry@bureclinic.com
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TC
Harry
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Matthews
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Salvary
D000505:Alopecia / Q000139:chemically induced* / Q000628:therapy; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D017320:HIV Protease Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D015497:HIV-1; D006801:Humans; D019469:Indinavir / Q000009:adverse effects* / Q000627:therapeutic use; D007508:Irritable Mood; D008297:Male; D008875:Middle Aged
D017320:HIV Protease Inhibitors; D019469:Indinavir