Effect of clinoptilolite on serum biochemical and haematological characters of broiler chickens during aflatoxicosis.
Clinoptilolite (CLI, a natural zeolite) incorporated into the diet at 1.5 and 2.5 per cent were evaluated for their ability to reduce the deleterious effects of 2.5 mg total aflatoxin (AF) kg(-1)diet on broiler chickens from 1 to 21 days of age. In total 360 broiler chicks were divided into six equal treatment groups (control, AF, CLI (1.5 per cent), AF plus CLI (1.5 per cent), CLI (2.5 per cent) and AF plus CLI (2.5 per cent)). When compared with the controls, AF treatment significantly decreased serum total protein, albumin, inorganic phosphorus, uric acid, total cholesterol and the values of haematocrit, red blood cell counts, mean corpuscular volume, haemoglobin, thrombocyte counts, percentage of monocyte counts; increased values of white blood cell and heterophil counts. The addition of CLI (1.5 per cent) and CLI (2.5 per cent) to the AF -containing diet reduced the adverse effects of AF and should be helpful in a solution to the aflatoxicosis problem in poultry.
Departments of Pharmacology and Toxicology, University of Selçuk, Konya, Turkey. hlsgz@hotmail.com
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Oğuz
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Keçeci
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Birdane
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Onder
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Kurtoğlu
D000348:Aflatoxins / Q000008:administration & dosage / Q000737:chemistry; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D002118:Calcium / Q000097:blood; D002645:Chickens / Q000378:metabolism* / Q000502:physiology; D002784:Cholesterol / Q000097:blood; D002855:Chromatography, Thin Layer / Q000662:veterinary; D004906:Erythrocyte Count / Q000662:veterinary; D005260:Female; D006400:Hematocrit / Q000662:veterinary; D006454:Hemoglobins / Q000032:analysis; D007958:Leukocyte Count / Q000662:veterinary; D008297:Male; D010758:Phosphorus / Q000097:blood; D011041:Poisoning / Q000517:prevention & control / Q000662:veterinary; D011506:Proteins / Q000032:analysis; D011897:Random Allocation; D012709:Serum Albumin / Q000032:analysis; D014527:Uric Acid / Q000097:blood; D017641:Zeolites / Q000737:chemistry*; D000096702:Aflatoxin Poisoning
D000348:Aflatoxins; D001786:Blood Glucose; D006454:Hemoglobins; D011506:Proteins; D012709:Serum Albumin; C083175:clinoptilolite; D017641:Zeolites; D014527:Uric Acid; D010758:Phosphorus; D002784:Cholesterol; D002118:Calcium