Central retinal artery occlusion in a patient homozygous for factor V Leiden.
OBJECTIVE
To report an association between central retinal artery occlusion and homozygosity for factor V Leiden.


METHODS
Case report.


RESULTS
A 48-year-old woman with sudden loss of visual acuity in her right eye caused by a central retinal artery occlusion showed abnormal resistance to activated protein C and was homozygous for the factor V Leiden gene.


CONCLUSIONS
Activated protein C resistance may be a risk factor for central retinal artery occlusion in young adults.
Larsson
J
J
Department of Ophthalmology, Lund University Hospital, Lund, Sweden. jorgen.larsson@oft.lu.se
D020016:Activated Protein C Resistance / Q000235:genetics*; D005165:Factor V / Q000235:genetics*; D005260:Female; D006720:Homozygote; D006801:Humans; D008875:Middle Aged; D017354:Point Mutation; D012170:Retinal Vein Occlusion / Q000235:genetics*
C095381:factor V Leiden; D005165:Factor V