[The possible role of alpha 2-macroglobulin in regulating the immune components of the brain in tick-borne encephalitis].
In tick-borne encephalitis certain immunopathological reactions develop in the tissues of the central nervous system; alpha 2-macroglobulin may serve as the marker of the activity of these reactions. The dynamic study of liquor taken from 16 patients with the meningeal and focal forms of tick-borne encephalitis (TBE), 8 patients with severe craniocerebral traumas accompanied by meningitis and 10 patients with osteochondrosis was made. As revealed in this study, in TBE patients the level of alpha 2-macroglobulin increases 3.5-fold and remains stable during the acute period of the disease.
Merzeniuk
Z A
ZA
Institute for Advanced Medical Training, Novokuznetsk, Russia.
Churliaev
Iu A
IuA
Nikiforova
N V
NV
Kuksinskiĭ
V A
VA
Lykova
O F
OF
Konysheva
T V
TV
D000208:Acute Disease; D015415:Biomarkers / Q000134:cerebrospinal fluid; D001921:Brain / Q000276:immunology*; D006259:Craniocerebral Trauma / Q000134:cerebrospinal fluid / Q000150:complications / Q000276:immunology; D004675:Encephalitis, Tick-Borne / Q000134:cerebrospinal fluid / Q000276:immunology*; D006801:Humans; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000209:etiology / Q000276:immunology; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid / Q000209:etiology / Q000276:immunology; D010007:Osteochondritis / Q000134:cerebrospinal fluid / Q000276:immunology; D013166:Spondylitis / Q000134:cerebrospinal fluid / Q000276:immunology; D000511:alpha-Macroglobulins / Q000134:cerebrospinal fluid / Q000276:immunology*
D015415:Biomarkers; D000511:alpha-Macroglobulins