Anatomic origin of the cervical N13 potential evoked by upper extremity stimulation.
There is a large consensus, based on converging evidence, that N13 recorded at lower cervical levels has a segmental postsynaptic origin in the gray matter of the cervical cord and that because of the orientation of its dipole field, the Cv6-anterior cervical derivation should be used whenever the diagnostic problem requires that this potential be assessed selectively in terms of latency and amplitude. The diagnostic utility of the lower cervical N13 recording in dorsal horn deafferentation and in lesions at the Cv6-Cv8 metameric levels has been validated in all types of cervical cord lesions. Unfortunately, such clear-cut conclusions do not apply to the N13 potential recorded at upper cervical levels. Currently, this component is not considered to provide enough reliable information, in addition to P13-P14 scalp recordings, to be used routinely in the diagnosis of cervicomedullary lesions.
Department of Functional Neurology and Epileptology, Neurological Hospital, Lyon, France.
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Mauguière
D000344:Afferent Pathways / Q000503:physiopathology; D001132:Arm / Q000294:innervation*; D002574:Cervical Vertebrae; D004558:Electric Stimulation; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D006801:Humans; D013116:Spinal Cord / Q000503:physiopathology*; D013118:Spinal Cord Diseases / Q000175:diagnosis / Q000503:physiopathology; D009435:Synaptic Transmission / Q000502:physiology