Diabetic rats transplanted with adult porcine islets and immunosuppressed with cyclosporine, mycophenolate mofetil, and leflunomide remain normoglycemic for up to 100 days.
Department of Transplantation Surgery, Karolinska Institute, Huddinge Hospital, Huddinge, Sweden. larswennberg@transpl.hs.sll.se
L
L
Wennberg
Z
Z
Song
J
J
Zhang
W
W
Bennet
S
S
Nava
S
S
Bari
B
B
Sundberg
O
O
Korsgren
C G
CG
Groth
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D016572:Cyclosporine / Q000627:therapeutic use*; D003921:Diabetes Mellitus, Experimental / Q000601:surgery; D004359:Drug Therapy, Combination; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016381:Islets of Langerhans Transplantation / Q000276:immunology / Q000502:physiology*; D007555:Isoxazoles / Q000627:therapeutic use*; D000077339:Leflunomide; D009173:Mycophenolic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use; D051381:Rats; D011917:Rats, Inbred Lew; D013552:Swine; D014183:Transplantation, Heterologous / Q000276:immunology / Q000502:physiology*
D001786:Blood Glucose; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D016572:Cyclosporine; D000077339:Leflunomide; D009173:Mycophenolic Acid