Nd:YAG laser corneal disruption as adjuvant treatment for infectious crystalline keratopathy.
OBJECTIVE
To report on the use of the Nd:YAG laser corneal disruption in the treatment of infectious crystalline keratopathy.


METHODS
Case report. A 52-year-old woman with infectious crystalline keratopathy unresponsive to topical antibiotics was treated with an Nd:YAG laser to the intrastromal crystals.


RESULTS
After Nd:YAG laser treatment, the infiltrate completely cleared within 4 weeks.


CONCLUSIONS
Nd:YAG laser treatment may be effective in disrupting the protective glycocalyx matrix within the intrastromal crystals, rendering the bacteria susceptible to topical antibiotics. This treatment should be considered for patients with infectious crystalline keratopathy clinically resistant to topical antibiotics.
University of Ottawa Eye Institute, Ottawa, Ontario, Canada.
H
H
Daneshvar
B
B
MacInnis
W G
WG
Hodge
D018441:Biofilms / Q000187:drug effects; D002437:Cefazolin / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D003316:Corneal Diseases / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery*; D003319:Corneal Stroma / Q000187:drug effects / Q000382:microbiology / Q000601:surgery*; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery*; D005260:Female; D006801:Humans; D017075:Laser Coagulation; D008875:Middle Aged; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery*; D013291:Streptococcus / Q000187:drug effects / Q000302:isolation & purification
D002511:Cephalosporins; D002437:Cefazolin