MR imaging findings in two patients with hepatic veno-occlusive disease following bone marrow transplantation.
The aim of this study was to describe the MRI features of veno-occlusive disease (VOD) following bone-marrow transplantation in two patients. The MRI features consisted of hepatomegaly, hepatic vein narrowing, periportal cuffing, gallbladder wall thickening, marked hyperintensity of the gallbladder wall on T2-weighted images, ascites, and pleural effusion. In one patient, signs of reduced portal venous flow velocity were also observed. It is concluded that the use of MRI as a complementary technique following non-conclusive US examination enabled a timely diagnosis of this life-threatening disease in both patients.
Julius Center for Patient Oriented Research, University Hospital, Utrecht, The Netherlands.
M A
MA
van den Bosch
L
L
van Hoe
D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation; D005260:Female; D006503:Hepatic Veins / Q000473:pathology; D006504:Hepatic Veno-Occlusive Disease / Q000175:diagnosis*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D011169:Portal Vein / Q000473:pathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy*; D012680:Sensitivity and Specificity