Mycophenolic acid in silage.
We examined 233 silage samples and found that molds were present in 206 samples with counts between 1 x 10(3) and 8.9 x 10(7) (mean, 4.7 x 10(6)) CFU/g. Mycophenolic acid, a metabolite of Penicillium roqueforti, was detected by liquid chromatography-mass spectrometry in 74 (32%) of these samples at levels ranging from 20 to 35,000 (mean, 1,400) microg/kg. This compound has well-known immunosuppressive properties, so feeding with contaminated silage may promote the development of infectious diseases in livestock.
Schneweis
I
I
Institute of Animal Hygiene, Faculty of Agriculture and Horticulture, Technische Universität München, 85354 Freising-Weihenstephan, Federal Republic of Germany.
Meyer
K
K
Hörmansdorfer
S
S
Bauer
J
J
D002853:Chromatography, Liquid; D015169:Colony Count, Microbial; D013058:Mass Spectrometry; D009173:Mycophenolic Acid / Q000032:analysis* / Q000378:metabolism; D010407:Penicillium / Q000302:isolation & purification* / Q000378:metabolism; D006109:Poaceae; D015203:Reproducibility of Results; D012820:Silage / Q000382:microbiology*; D003313:Zea mays
D009173:Mycophenolic Acid