Treatment of early-onset dystonia: update and a new perspective.
Dystonia is a rare disease of childhood, often leading to devastating functional impairment. Medical treatment is reviewed, although its efficacy is often limited. Recent advances in functional neurosurgery have opened up a new field in the management of dystonic patients, and the results of deep brain stimulation are given particular emphasis.
Roubertie
A
A
Pediatric Neurosurgery, Gui de Chauliac Hospital, Montpellier, France. a_roubertie@hotmail.com
Echenne
B
B
Cif
L
L
Vayssiere
N
N
Hemm
S
S
Coubes
P
P
D000367:Age Factors; D001569:Benzodiazepines / Q000627:therapeutic use*; D001921:Brain / Q000601:surgery*; D018680:Cholinergic Antagonists / Q000627:therapeutic use*; D018491:Dopamine Agonists / Q000627:therapeutic use*; D018492:Dopamine Antagonists / Q000627:therapeutic use*; D004421:Dystonia / Q000188:drug therapy* / Q000209:etiology / Q000601:surgery*; D004558:Electric Stimulation; D018755:GABA Agonists / Q000627:therapeutic use*; D006801:Humans; D013238:Stereotaxic Techniques; D016896:Treatment Outcome
D018680:Cholinergic Antagonists; D018491:Dopamine Agonists; D018492:Dopamine Antagonists; D018755:GABA Agonists; D001569:Benzodiazepines