Congenital ocular motor apraxia with autosomal dominant inheritance.
OBJECTIVE
To document congenital ocular motor apraxia in five first-degree relatives.


METHODS
Case series. Five family members with a history of horizontal head thrusting had neuro-ophthalmologic evaluation. Magnetic resonance imaging of the brain was obtained in the proband.


RESULTS
Four siblings (one boy and three girls) had congenital ocular motor apraxia. The father had head thrusting as a child and displayed residual signs of the disorder. Magnetic resonance imaging disclosed no central nervous system abnormalities in the father.


CONCLUSIONS
Congenital ocular motor apraxia can be inherited as an autosomal dominant trait.
Phillips
P H
PH
Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Brodsky
M C
MC
Henry
P M
PM
D000328:Adult; D001072:Apraxias / Q000235:genetics* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D015785:Eye Diseases, Hereditary / Q000235:genetics* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D015835:Ocular Motility Disorders / Q000151:congenital* / Q000503:physiopathology; D010375:Pedigree; D012438:Saccades