Cancer of the anus.
Cancers of the anus, whether keratinizing squamous, nonkeratinizing, clear-cell, or melanoma, are infrequent neoplasms. Small keratinizing (<4 cm2) with no deep invasion can be controlled by local excision or laser ablation, but larger ones may be treated by chemoirradiation, restricting abdominoperineal resection to recurrences. Neither melanomas nor clear-cell cancers are curable, and local control is the surgical objective. Prophylactic groin dissection is not required but, for enlarged nodes or in the presence of a positive sentinel node biopsy, may be curative in many cases and palliative in all.
J. Graham Brown Cancer Center, Louisville, Kentucky 40202, USA. jsspra01@ulkyvm.louisville.edu
J S
JS
Spratt
D000005:Abdomen / Q000601:surgery; D001003:Anal Canal / Q000601:surgery; D000714:Anastomosis, Surgical; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001005:Anus Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D003937:Diagnosis, Differential; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D010502:Perineum / Q000601:surgery; D011879:Radiotherapy Dosage
D000970:Antineoplastic Agents