Hypoglycaemic activity of Ocimum gratissimum in rats.
The hypoglycaemic effect of the methanolic extract of Ocimum gratissimum leaves was evaluated in normal and alloxan-induced diabetic rats. Intraperitoneal injection of the extract (400 mg/kg) significantly reduced plasma levels both in normal and diabetic rats by 56 and 68%, respectively.
Department of Pharmacology and Clinical Pharmacy, University of Jos, Jos, Nigeria.
J C
JC
Aguiyi
C I
CI
Obi
S S
SS
Gang
A C
AC
Igweh
D000496:Alloxan; D000818:Animals; D001786:Blood Glucose / Q000187:drug effects; D003920:Diabetes Mellitus / Q000188:drug therapy*; D003921:Diabetes Mellitus, Experimental; D004195:Disease Models, Animal; D007004:Hypoglycemic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D016488:Medicine, African Traditional; D018649:Ocimum basilicum; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology; D018515:Plant Leaves; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts; D000496:Alloxan