Dimerization of an Inactive Fragment of Huperzine A Produces a Drug with Twice the Potency of the Natural Product This work was supported by the Research Grants Council of Hong Kong (HKUST6156/97M), the Biotechnology Research Institute (HKUST), the Mayo Foundation, and the Istituto Pasteur Fondazione Cenci Bolognetti (E.P.). We thank Prof. X. C. Tang (Shanghai Institute of Materia Medica) for a gift of (-)-1.
Carlier
PR
Department of Chemistry and Molecular Neuroscience Center Hong Kong University of Science and Technology Clear Water Bay, Kowloon (Hong Kong).
Du
DM
Han
YF
Liu
J
Perola
E
Williams
ID
Pang
YP