Structure and Mechanism in Cinchona Alkaloid Chemistry: Aqueous Hydrolysis Proceeds with Complete Inversion or Complete Retention of Configuration We thank Stefanie Röper for experimental contributions, Olaf Schrake for discussion, Ulrike Eggert and Lars Ole Haustedt for their help, Dr. Hofer for NMR analysis, and two referees for their critical comments. Our work was supported by the Friedrich-Naumann-Stiftung (PhD. Fellowship for W.M.B.), Chininfabrik Buchler GmbH (gift of Cinchona alkaloids) and the Fonds der Chemischen Industrie.
Institut für Organische Chemie, Universität Hannover Schneiderberg 1B, 30167 Hannover (Germany).
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Braje
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Holzgrefe
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Wartchow
HM
Hoffmann