Insoluble beta-cyclodextrin polymer for capillary gas chromatographic separation of enantiomers and isomers.
An insoluble beta-cyclodextrin polymer cross-linked with identified epichiorohydrin has been prepared; its structure was identified by means of infrared and 13C NMR spectra. Three capillary columns have been coated with the polymer treated by ultrasonication by three coating methods. Chromatographic characteristics such as column efficiency, thermal stability and polarity, have been studied, and two kinds of disubstituted benzene isomers and eight pairs of enantiomers have been separated on the three capillary columns. The results show that the beta-cyclodextrin polymer is suitable for use as a capillary gas chromatographic stationary phase, and that the column, prepared by loading beta-cyclodextrin polymer stationary phase with 50% methyl-50% phenylsilicone (OV-17), shows good chromatographic properties in separating enantiomers and positional isomers.
Yi
J M
JM
Department of Chemical Engineering, Yueyang Normal University, Hunan, China.
Tang
K W
KW
D002849:Chromatography, Gas / Q000379:methods*; D003505:Cyclodextrins / Q000737:chemistry*; D007536:Isomerism; D009682:Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D047392:beta-Cyclodextrins
D003505:Cyclodextrins; D047392:beta-Cyclodextrins; C031215:betadex