Laryngeal leiomyosarcoma.
We report one case of leiomyosarcoma (LMS) of the larynx occurring in a patient with a history of immunosuppressive therapy, and offer a critical review of the literature. Epstein-Barr virus (EBV) genome was not identified in the neoplastic cells. The patient was treated with endoscopic resection and post-operative radiotherapy. Lung metastasis and thyroid infiltration became evident 14 months following treatment despite the absence of laryngeal recurrence. Progressive decline occurred and the patient died 15 months after diagnosis.
Department of Otolaryngology-Head and Neck Surgery, University of Udine, Italy. clorl@dsc.uniud.it
G
G
Marioni
G
G
Bertino
L
L
Mariuzzi
A M
AM
Bergamin-Bracale
M
M
Lombardo
C A
CA
Beltrami
D000328:Adult; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000628:therapy; D008175:Lung Neoplasms / Q000556:secondary / Q000628:therapy; D013964:Thyroid Neoplasms / Q000556:secondary / Q000628:therapy