Rapid three-dimensional MR imaging method for tracking a bolus of contrast agent through the brain.
A gradient-echo three-dimensional magnetic resonance imaging technique (principles of echo shifting with a train of observations, or PRESTO) is presented for use in tracking a bolus of paramagnetic contrast agent through the brain. The approach combines a segmented echo-planar type of acquisition with echo shifting, which leads to echo times that are longer than the repetition time. Unlike echo-planar imaging, the method maintains image resolution despite drastic T2* changes and frequency shifts.
National Institutes of Health Laboratory of Diagnostic Radiology Research, Office of the Director and In Vivo NMR Research Center, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA. gelderen@helix.nih.gov
P
P
van Gelderen
C
C
Grandin
J R
JR
Petrella
C T
CT
Moonen
D000328:Adult; D001921:Brain / Q000033:anatomy & histology*; D002560:Cerebrovascular Circulation / Q000502:physiology; D003287:Contrast Media / Q000008:administration & dosage; D017352:Echo-Planar Imaging / Q000379:methods*; D005260:Female; D005583:Fourier Analysis; D019786:Gadolinium DTPA / Q000008:administration & dosage; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012815:Signal Processing, Computer-Assisted; D013997:Time Factors
D003287:Contrast Media; D019786:Gadolinium DTPA