Electron microscopic study of Langerhans cell histiocytosis.
Among the several forms of Langerhans cell histocytosis (LCH), Letterer-Siwe disease is the most acute disseminated multisystemic variant. The course of Letterer-Siwe disease is usually rapid and fatal. We report here a cases of Letterer-Siwe disease which showed a good response to chemotherapy. We also describe the unusual ultrastructural findings in the histiocyte-like cells in this case.
Department of Dermatology, University of Occupational and Environmental Health, Kitakyushu, Japan.
M
M
Kobayashi
O
O
Yamamoto
Y
Y
Suenaga
M
M
Asahi
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D001707:Biopsy, Needle; D005260:Female; D005500:Follow-Up Studies; D006644:Histiocytes / Q000648:ultrastructure*; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007223:Infant; D008854:Microscopy, Electron; D016896:Treatment Outcome