[The effect of estrogen receptor level on the prognosis of the elderly breast cancer patients].
OBJECTIVE
To evaluate the effect of estrogen receptor (ER) on the prognosis of the elderly female breast cancer patients and the guidance for their post-operation therapy.


METHODS
134 cases of the elderly female breast cancer patients (> or = 60 year-old) were divided into two groups depending on their ER level. Kaplan-Meier method was used to estimate disease-free servival (DFS) rate from the date of surgery.


RESULTS
There were 88 patients in ER (+) group and 46 patients in ER (-) group. The medium follow-up of the ER (+) and the ER (-) group was 92.5 and 85.5 months, respectively. The incidence of recurrence and metastasis was 20.5% (18/88) in the ER (+) group and 41.3% (19/46) in the ER (-) group (P < 0.02).


CONCLUSIONS
Estrogen receptor is a reference factor to predict prognosis of breast cancer in elderly patients.
Beijing Institute for Cancer Research.
B C
BC
Xing
L
L
He
Y
Y
Wang
D000368:Aged; D001943:Breast Neoplasms / Q000378:metabolism* / Q000601:surgery; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D011960:Receptors, Estrogen / Q000378:metabolism*; D011980:Receptors, Progesterone / Q000378:metabolism; D012189:Retrospective Studies
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone