Reversible renal failure after treatment with omeprazole.
Omeprazole is a proton pump inhibitor widely used in the treatment of gastro-esophageal reflux disease and peptic ulcer disease. In a 73-year-old man we describe renal failure due to acute interstitial nephritis after use of omeprazol during 4 months. Unexpected renal failure without signs of hydronephrosis should always provoke awareness of drug reaction, omeprazole being one of the possible drugs.
Sint Franciscus Gasthuis, Department of Internal Medicine, Rotterdam, The Netherlands. aukepost@hotmail.com
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D058186:Acute Kidney Injury / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D000368:Aged; D004791:Enzyme Inhibitors / Q000009:adverse effects*; D005764:Gastroesophageal Reflux / Q000150:complications / Q000188:drug therapy; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D009853:Omeprazole / Q000009:adverse effects*; D020127:Recovery of Function / Q000187:drug effects; D016896:Treatment Outcome
D004791:Enzyme Inhibitors; D009853:Omeprazole