Increased need for medical interventions in infants with velocardiofacial (deletion 22q11) syndrome.
Ten of 12 patients diagnosed with deletion 22q11.2 in infancy required a total of 26 hospitalizations during their first year of life. After heart disease, feeding and respiratory problems were the most frequent reasons for intervention.
Hopkin
R J
RJ
Division of Human Genetics and the Craniofacial Center, Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
Schorry
E K
EK
Bofinger
M
M
Saal
H M
HM
D000015:Abnormalities, Multiple / Q000453:epidemiology / Q000235:genetics / Q000628:therapy*; D002872:Chromosome Deletion; D002892:Chromosomes, Human, Pair 22; D019468:Disease Management; D005247:Feeding Behavior; D005260:Female; D006330:Heart Defects, Congenital / Q000453:epidemiology / Q000235:genetics / Q000628:therapy*; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009820:Ohio / Q000453:epidemiology; D012141:Respiratory Tract Infections / Q000453:epidemiology; D012189:Retrospective Studies; D013391:Sucking Behavior