[Immunological aspects of modern forms of pneumoconioses].
The authors determined pneumoconiosis as a chronic diffuse or diffuse and granulomatous pneumonitis with pulmonary fibrosis. The article deals with identification of lymphocytes subpopulations through monoclonal antibodies, details peculiarities of cellular immunity in pneumoconiosis patients, contains new data on LgE-dependent inflammatory mechanisms including specific response to industrial dust allergens. Discussion covers ways of immune correction therapy and immune prophylactics in accordance with phases of body response to homotoxins produced due to exogenous dust load.
Izmerov
N F
NF
Dueva
L A
LA
Milishnikova
V V
VV
D000911:Antibodies, Monoclonal / Q000276:immunology; D002908:Chronic Disease; D016207:Cytokines / Q000627:therapeutic use*; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D011009:Pneumoconiosis / Q000188:drug therapy* / Q000276:immunology*
D000911:Antibodies, Monoclonal; D016207:Cytokines; D007073:Immunoglobulin E