[Comparison of angiotensin receptor antagonists and angiotensin converting enzyme inhibitors in arterial hypertension].
By blocking the renin-angiotensin system, angiotensin converting enzyme inhibitors and more recently introduced angiotensin II receptor antagonists are two important classes of antihypertensive drugs. Whether one class is superior to the other is presently unknown. Their antihypertensive efficacy is comparable. Angiotensin II receptor antagonists are particularly well tolerated but the converting enzyme inhibitors have broader indications. The results of the large studies with morbidity and mortality end-points are awaited to better define the place of the angiotensin II antagonists in monotherapy and in combination.
Service de Néphrologie, C.H.U. Sart Tilman, Liège.
J M
JM
Krezsinski
J
J
Sternon
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000493:pharmacokinetics / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D012084:Renin-Angiotensin System / Q000187:drug effects
D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents