[Decreasing prevalence of Helicobacter pylori: a consequence of treatment of gastroduodenal ulcers].
Four patients with gastroduodenal ulcers in the absence of Helicobacter pylori illustrate the decreasing prevalence of this microorganism. One was a 19-year-old boy with nausea, diarrhoea and weight loss caused by multiple gastroduodenal ulcers due to the Zollinger-Ellison syndrome. Another was a 36-year-old man with abdominal discomfort caused by an ulcer due to Crohn's disease. The other two cases concerned a 29-year-old man and a 68-year-old woman with relapsing ulcer disease and active bleeding, in whom no causal factors could be determined. Recent studies suggest a decreasing prevalence of H. pylori leading to both a relative and an absolute decrease of gastroduodenal ulcers attributed to H. pylori. Future treatment strategies will have to take these altered prevalence rates into consideration.
van der Weerd
N C
NC
Academisch Ziekenhuis Vrije Universitet, afd. Gastro-enterologie, Amsterdam.
Cats
A
A
Thijs
J C
JC
Festen
H P
HP
Meuwissen
S G
SG
Kuipers
E J
EJ
D000328:Adult; D000368:Aged; D003424:Crohn Disease / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D016481:Helicobacter Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008551:Melena / Q000209:etiology; D009426:Netherlands / Q000453:epidemiology; D010437:Peptic Ulcer / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology / Q000382:microbiology; D015995:Prevalence; D012008:Recurrence; D015043:Zollinger-Ellison Syndrome / Q000150:complications / Q000175:diagnosis*