New cyclic peptide and bisindolyl benzenoid metabolites from the sclerotia of Aspergillus sclerotiorum.
Scleramide (1), a new cyclic hexapeptide, and a new oxidized bisindolyl benzenoid derivative (2' '-oxoasterriquinol D methyl ether, 2) were isolated from extracts of the sclerotia of Aspergillus sclerotiorum (NRRL 5167). The structures of these compounds were determined by analysis of 1D and 2D NMR experiments.
Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.
A C
AC
Whyte
B K
BK
Joshi
J B
JB
Gloer
D T
DT
Wicklow
P F
PF
Dowd
D001230:Aspergillus / Q000737:chemistry*; D001555:Benzene Derivatives / Q000737:chemistry / Q000302:isolation & purification*; D007211:Indoles / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification*
D001555:Benzene Derivatives; D007211:Indoles; D010456:Peptides, Cyclic