The breast cancer information core: database design, structure, and scope.
The Breast Cancer Information Core (BIC) is an open access, on-line mutation database for breast cancer susceptibility genes. In addition to creating a catalogue of all mutations and polymorphisms in breast cancer susceptibility genes, a principle aim of the BIC is to facilitate the detection and characterization of these genes by providing technical support in the form of mutation detection protocols, primer sequences, and reagent access. Additional information at the site includes a literature review compiled from published studies, links to other internet-based, breast cancer information and research resources, and an interactive discussion forum which enables investigators to post or respond to questions and/or comments on a bulletin board. Hum Mutat 16:123-131, 2000. Published 2000 Wiley-Liss, Inc.
Szabo
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Unit of Genetic Epidemiology, International Agency for Research on Cancer, Lyon, France.
Masiello
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Ryan
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Brody
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LC
D000465:Algorithms; D019313:BRCA1 Protein / Q000145:classification / Q000235:genetics; D024682:BRCA2 Protein; D001943:Breast Neoplasms / Q000145:classification / Q000235:genetics*; D003195:Computer Communication Networks; D003628:Database Management Systems; D016208:Databases, Factual / Q000706:statistics & numerical data / Q000639:trends; D005260:Female; D006239:Haplotypes; D006801:Humans; D008297:Male; D009154:Mutation / Q000235:genetics; D009363:Neoplasm Proteins / Q000145:classification / Q000235:genetics; D010051:Ovarian Neoplasms / Q000145:classification / Q000235:genetics; D012984:Software; D009626:Terminology as Topic; D014157:Transcription Factors / Q000145:classification / Q000235:genetics
D019313:BRCA1 Protein; D024682:BRCA2 Protein; D009363:Neoplasm Proteins; D014157:Transcription Factors