Nonbenzamidine compounds as selective factor Xa inhibitors.
Nonbenzamidine compounds (imidazole, pyridine, pyrimidine, and thiazole derivatives) as selective serine protease factor Xa inhibitors are discussed.
He
W
W
Department of Medicinal Chemistry, Aventis Pharmaceuticals, Collegeville, PA 19426, USA. wei.he@aventis.com
Hanney
B
B
Myers
M R
MR
Spada
A P
AP
Brown
K
K
Colussi
D
D
Chu
V
V
D001550:Benzamidines / Q000737:chemistry / Q000494:pharmacology; D065427:Factor Xa Inhibitors; D015842:Serine Proteinase Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D001550:Benzamidines; D065427:Factor Xa Inhibitors; D015842:Serine Proteinase Inhibitors