Evaluation of pulmonary gas exchange after lobectomy and simple thoracotomy.
Postoperative influence of simple thoracotomy and lobectomy on pulmonary gas exchange was investigated in 10 patients undergoing thoracotomy and lobectomy (L group) and 10 patients with simple thoracotomy (ST group). Gas exchange was assessed with hot-wire mass spectrometry and blood gas analyses preoperatively and postoperatively at 1, 3, 6, 12, 24 and 48 h and on days 4, 6 and 13. The preoperative values of alveolar-arterial oxygen tension gradient (AaDO2), ventilation-perfusion mismatch (V(A)/Q) and circulatory shunt (Qs/Qt) were maintained in the ST group. In the L group, however, AaDO2 and Qs/Qt showed good maintenance of gas exchange for only 6-12h after lobectomy and then deteriorated because of peripheral atelectasis, resulting in poorer values than those in the ST group on days 4 and 13. Careful postoperative management, including pulmonary toilet, is essential for maintenance of gas exchange and prevention of pulmonary complications.
Sekine
Y
Y
Department of Surgery, Institute of Pulmonary Cancer Research, Chiba University School of Medicine, Japan. ysekine@hotmail.com
Miyata
Y
Y
Yamada
K
K
Yamada
H
H
Yasukawa
T
T
Yoshida
S
S
Saitoh
Y
Y
Fujisawa
T
T
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary / Q000601:surgery*; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011013:Pneumonectomy; D011183:Postoperative Complications / Q000503:physiopathology*; D011650:Pulmonary Alveoli / Q000503:physiopathology; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D013908:Thoracotomy; D014692:Ventilation-Perfusion Ratio / Q000502:physiology
D010100:Oxygen