Emerging themes in medicinal glycoscience.
The recognition of complex carbohydrates and glycoconjugates as mediators of important biological processes has stimulated investigation into their therapeutic potential. New approaches for the simplification of glycoconjugate synthesis are overcoming the limitations of existing methods and providing a diverse array of these biomolecules. As the accessibility of glycoconjugates increases, carbohydrate-based constructs are becoming available for analysis as medicinal agents in a wide range of therapies.
Koeller
K M
KM
Department of Chemistry, The Scripps Research Institute and Skaggs Institute for Chemical Biology, La Jolla, CA 92037, USA.
Wong
C H
CH
D000890:Anti-Infective Agents / Q000737:chemistry / Q000627:therapeutic use; D002240:Carbohydrate Sequence; D006001:Glycoconjugates / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans; D008969:Molecular Sequence Data
D000890:Anti-Infective Agents; D006001:Glycoconjugates