alphaGAL ligation with a lectin induces activation and resistance to the proinflammatory effects of human complement on porcine endothelium.
Grehan
J F
JF
Departments of Surgery and Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
Kulick
D M
DM
Guzman-Paz
M
M
Bolman
R M
RM
Dalmasso
A P
AP
D000818:Animals; D003165:Complement System Proteins / Q000502:physiology*; D004187:Disaccharides / Q000276:immunology*; D004730:Endothelium, Vascular / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D066298:In Vitro Techniques; D007249:Inflammation; D007668:Kidney; D037102:Lectins / Q000494:pharmacology*; D008954:Models, Biological; D037121:Plant Lectins; D013552:Swine; D014183:Transplantation, Heterologous
D004187:Disaccharides; C045475:Griffonia simplicifolia lectins; D037102:Lectins; D037121:Plant Lectins; C055075:galactosyl-(1-3)galactose; D003165:Complement System Proteins