Nonbenzamidine compounds as selective factor Xa inhibitors.
Nonbenzamidine compounds (imidazole, pyridine, pyrimidine, and thiazole derivatives) as selective serine protease factor Xa inhibitors are discussed.
Department of Medicinal Chemistry, Aventis Pharmaceuticals, Collegeville, PA 19426, USA. wei.he@aventis.com
W
W
He
B
B
Hanney
M R
MR
Myers
A P
AP
Spada
K
K
Brown
D
D
Colussi
V
V
Chu
D001550:Benzamidines / Q000737:chemistry / Q000494:pharmacology; D065427:Factor Xa Inhibitors; D015842:Serine Proteinase Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D001550:Benzamidines; D065427:Factor Xa Inhibitors; D015842:Serine Proteinase Inhibitors