Orbital involvement as the initial manifestation of sarcoidosis: magnetic resonance imaging findings.
A 74-year-old man had diplopia, painful right ophthalmoplegia, proptosis, conjunctival injection, and facial skin lesions. Magnetic resonance imaging (MRI) revealed infiltration of the right intraorbital adipose tissue. Lesions were mixed low- and high-signal on T2-weighted images and enhanced on fat-suppressed T1-weighted postcontrast images. A skin biopsy revealed numerous noncaseating granulomas consistent with sarcoidosis. Treatment with corticosteroids and chlorambucil led to a full clinical recovery. Sarcoidosis should be considered in the evaluation of orbital pseudotumor in elderly patients, even if no systemic manifestations of sarcoidosis are present.
Department of Neurology, University at Buffalo, State University of New York, School of Medicine and Biomedical Sciences, Buffalo, NY, USA.
Z A
ZA
Shaikh
R
R
Bakshi
S J
SJ
Greenberg
E J
EJ
Fine
A
A
Shatla
N S
NS
Lincoff
D000368:Aged; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009915:Orbit / Q000473:pathology; D009916:Orbital Diseases / Q000175:diagnosis*; D012507:Sarcoidosis / Q000175:diagnosis*