Feedback-controlled laser-mediated cartilage reshaping.
OBJECTIVE
To demonstrate feedback-controlled laser-mediated cartilage reshaping using dynamic measurements of tissue optical properties and radiometric surface temperatures.


METHODS
Flat cartilage specimens were reshaped into curved configurations using a feedback-controlled laser device.


METHODS
Fresh porcine nasal septum, stripped of perichondrium and cut into uniform strips (25 x 10 x 1.5-2.1 mm) with a custom guillotine microtome.


METHODS
Cartilage specimens secured in a cylindrical reshaping jig (2.5 cm in diameter) and irradiated with an Nd:YAG laser (lambda = 1.32 microns, 25 W/cm2, 50-Hz pulse repetition rate). During laser irradiation, radiometric surface temperature was measured along with changes in forward-scattered light from a diode probe laser (lambda = 650 nm, 5 mW), using a lock-in detection technique. Sequential irradiation of the specimen outer surface was made (3 laser passes). Characteristic changes in tissue temperature and light-scattering signals were used to terminate laser irradiation.


RESULTS
Effective reshaping was accomplished for both thin (1.5-mm) and thick (2.1-mm) specimens. Following reshaping, specimens were stored in saline solution at 4 degrees C for 21 days. No return to the original flat configuration was noted during this period.


CONCLUSIONS
The prototype device effectively reshapes flat native porcine cartilage into curve configurations. The use of optical and thermal signals provides effective feedback control for optimizing the reshaping process.
Beckman Laser Institute and Medical Clinic, University of California, Irvine, USA. bjfwong@bli.uci.edu
B J
BJ
Wong
T E
TE
Milner
A
A
Harrington
J
J
Ro
X
X
Dao
E N
EN
Sobol
J S
JS
Nelson
D000818:Animals; D002356:Cartilage / Q000601:surgery*; D004867:Equipment Design; D005246:Feedback; D053685:Laser Therapy / Q000295:instrumentation*; D009300:Nasal Septum / Q000601:surgery; D019651:Plastic Surgery Procedures; D013552:Swine; D013696:Temperature