Managing the neurotoxicity of paclitaxel (Taxol) and docetaxel (Taxotere) with neurotrophic factors.
Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA.
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D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000633:toxicity*; D000077143:Docetaxel; D051100:Glial Cell Line-Derived Neurotrophic Factor; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000494:pharmacology; D020932:Nerve Growth Factor / Q000494:pharmacology*; D009414:Nerve Growth Factors; D009419:Nerve Tissue Proteins / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects*; D017239:Paclitaxel / Q000031:analogs & derivatives* / Q000633:toxicity*; D043823:Taxoids
D000972:Antineoplastic Agents, Phytogenic; C495039:GDNF protein, human; D051100:Glial Cell Line-Derived Neurotrophic Factor; D009414:Nerve Growth Factors; D009419:Nerve Tissue Proteins; D043823:Taxoids; D000077143:Docetaxel; D007334:Insulin-Like Growth Factor I; D020932:Nerve Growth Factor; D017239:Paclitaxel