[Evaluation of the possible use of the National Cancer Registry for survival analysis of children and youth with selected malignant neoplasms--tumors in 1990-1995 in Poland].
This paper is the continuation of previous research described in the article "Evaluation of the possibility of using the National Cancer Registry in survival analysis of children and youth with selected malignancies-leukaemias and lymphomas in 1990-1995 year in Poland" on the basis of the National Cancer Registry data concerning tumours. Tumours comprise 62.0% of total number of cases and 56.6% of total number of deaths from cancer in children and youth. Modern methods of statistical analysis such as Cox regression and Kaplan-Meier survival curves method have been used. The conclusion formulated in the previous paper is still valid. Despite the fact that the Registry is not designed for survival analysis, they are possible and are the basis of many important findings. The crucial factor for the value of the Register in the time of advanced statistical analysis and computer methods is organisation of the Registry and data quality. Organizational and clinical conclusions have been formulated. Organizational conclusions concern mainly the principles of conducting the Registry namely introducing of International Classification of Diseases for Oncology (ICD-O) and extending it from 2 to 5 years the period of observation. The leading clinical conclusions are: lack of improvement in prognosis in the 6 years period 1990-1995 and crucial importance of early diagnosis of oncological disease for survival time. Further clinical conclusions concerning the impact of treatment cannot be stated on the basis of the Registry data.
Zakład Zdrowia Publicznego i Medycyny Szkolnej, Instytut Matki i Dziecka w Warszawie. imid@imid.med.pl
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Mielniczuk
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Borkowski
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Szymborski
D000293:Adolescent; D017677:Age Distribution; D002648:Child; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D009367:Neoplasm Staging; D009369:Neoplasms / Q000145:classification / Q000453:epidemiology / Q000401:mortality*; D011044:Poland / Q000453:epidemiology; D011379:Prognosis; D012042:Registries; D012044:Regression Analysis; D017678:Sex Distribution; D016019:Survival Analysis