Bcl-2 expression in pig cells suppresses the apoptosis caused by human perforin/granzymes- or FasL/Fas-mediated cytotoxicity.
Fujiwara
I
I
Second Department of Surgery, Kyoto Prefectural University of Medicine, Kamigyo, Kyoto, Japan.
Nakajima
H
H
Mizuta
N
N
Sakaguchi
K
K
Yoshimura
N
N
Yamagishi
H
H
Oka
T
T
D000818:Animals; D000910:Antibodies, Heterophile / Q000276:immunology; D000920:Antibody-Dependent Cell Cytotoxicity; D017209:Apoptosis / Q000276:immunology*; D002460:Cell Line; D053222:Fas Ligand Protein; D019254:Genes, bcl-2; D006801:Humans; D007668:Kidney; D008562:Membrane Glycoproteins / Q000276:immunology*; D051379:Mice; D054353:Perforin; D052899:Pore Forming Cytotoxic Proteins; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism*; D012697:Serine Endopeptidases / Q000378:metabolism*; D013552:Swine; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D014162:Transfection; D019014:fas Receptor / Q000276:immunology*
D000910:Antibodies, Heterophile; C505661:FASLG protein, human; D053222:Fas Ligand Protein; C505658:Fasl protein, mouse; D008562:Membrane Glycoproteins; D052899:Pore Forming Cytotoxic Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D019014:fas Receptor; D054353:Perforin; D012697:Serine Endopeptidases