Liver lesions: intermittent second-harmonic gray-scale US can increase conspicuity with microbubble contrast material-early experience.
The authors investigated the effect of intermittent second-harmonic gray-scale (ISHGS) ultrasonography (US) with SH U 508A microbubbles on the conspicuity of focal liver lesions. Twenty-three patients were included in the study. Images were analyzed subjectively and quantitatively. Objective lesion conspicuity was increased. In 12 of the 15 patients with liver malignancy, gray-scale defects were seen in previously unsuspected areas. ISHGS US may improve the sensitivity of US for liver lesions.
Department of Imaging, Hammersmith Hospital, Du Cane Road, London W12 0HS, United Kingdom.
R A
RA
Heckemann
D O
DO
Cosgrove
M J
MJ
Blomley
R J
RJ
Eckersley
C J
CJ
Harvey
Y
Y
Mine
D000328:Adult; D000368:Aged; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging; D002277:Carcinoma / Q000000981:diagnostic imaging; D003287:Contrast Media / Q000008:administration & dosage; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000000981:diagnostic imaging; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007262:Infusions, Intravenous; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D019047:Phantoms, Imaging; D011134:Polysaccharides / Q000008:administration & dosage; D012680:Sensitivity and Specificity; D014465:Ultrasonics; D014463:Ultrasonography; D014743:Videotape Recording
D003287:Contrast Media; D011134:Polysaccharides; C059891:SHU 508