Tracing the evolution of vertebrate fibrillar collagens from an ancestral alpha chain.
From considerations of gene structure, phylogenetic analysis, modular organisation of related proteins and fibril shapes, we suggest a model for the evolution of contemporary vertebrate fibrillar collagens from a common ancestral alpha chain.
Exposito
J
J
Institut de Biologie et Chimie des Protéines, CNRS, Unité Propre de Recherche 412, Université Claude Bernard, 7 passage du Vercors, 69367 cedex 07, Lyon, France. jy.exposito@ibcp.fr
Cluzel
C
C
Lethias
C
C
Garrone
R
R
D000818:Animals; D003094:Collagen / Q000235:genetics*; D019143:Evolution, Molecular; D006801:Humans; D011347:Procollagen / Q000235:genetics*; D017434:Protein Structure, Tertiary; D014714:Vertebrates
D011347:Procollagen; D003094:Collagen