Molecularly imprinted fluorescent-shift receptors prepared with 2-(trifluoromethyl)acrylic acid.
Methacrylic acid (MAA) and 2-(trifluoromethyl)acrylic acid (TFMAA) were used to prepare molecularly imprinted polymers exhibiting diastereoselectivity for cinchona alkaloids. Fluorescent spectra of the cinchona alkaloid exhibit a characteristic shift through binding to these polymer particles, originating most likely from the highly acidic residues in the imprinted polymers acting as a proton donator. Our results show that TFMAA based imprinted polymers can be used as polymer reagents for quantitating the cinchona alkaloid bound to the polymers without bound/free separation.
Matsui
J
J
Laboratory of Synthetic Biochemistry, Faculty of Information Sciences, Hiroshima City University, Japan.
Kubo
H
H
Takeuchi
T
T
D000179:Acrylates / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D002930:Cinchona Alkaloids / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry; D007202:Indicators and Reagents; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
C411824:2-(trifluoromethyl)acrylic acid; D000179:Acrylates; D002930:Cinchona Alkaloids; D005456:Fluorescent Dyes; D007202:Indicators and Reagents