[Role of metabolic vitreous alkalosis and redox processes in pathogenesis of senile macular degeneration].
Studies of acid-base balance (pH-metry) of the vitreous in 32 patients with senile macular degenerations and theoretical studies showed an important role of redox processes in the pathogenesis of senile macular degeneration, namely, intensification of free-radical oxidation, leading to metabolic alkalosis of the vitreous.
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Smetankin
D000368:Aged; D000471:Alkalosis / Q000150:complications* / Q000378:metabolism; D018450:Disease Progression; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008268:Macular Degeneration / Q000209:etiology* / Q000378:metabolism; D010084:Oxidation-Reduction; D014822:Vitreous Body / Q000378:metabolism*