Biochemistry. All in the ubiquitin family.
The job of a protein can be altered by addition of molecules such as ubiquitin or the related ubiquitin-like modifiers, which bring about changes in the protein's localization, conformation, or its interactions with other proteins. In a comprehensive Perspective, Hochstrasser brings us up to date with the many new members of the ubiquitin modifier family and their multitudinous and diverse protein targets.
Hochstrasser
M
M
Yale University, Department of Molecular Biophysics and Biochemistry, 266 Whitney Avenue, New Haven, CT 06520, USA. mark.hochstrasser@yale.edu
D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D000818:Animals; D001343:Autophagy; D000071193:Autophagy-Related Protein 7; D001665:Binding Sites; D002467:Cell Nucleus / Q000378:metabolism; D019143:Evolution, Molecular; D005656:Fungal Proteins / Q000737:chemistry / Q000378:metabolism*; D008025:Ligases / Q000378:metabolism; D008956:Models, Chemical; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*; D025842:SUMO-1 Protein; D029701:Saccharomyces cerevisiae Proteins; D044767:Ubiquitin-Protein Ligases; D014452:Ubiquitins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D015003:Yeasts / Q000378:metabolism
C114830:ATG7 protein, S cerevisiae; D005656:Fungal Proteins; D011506:Proteins; C111706:RUB1 protein, S cerevisiae; D025842:SUMO-1 Protein; D029701:Saccharomyces cerevisiae Proteins; C406282:URM1 protein, S cerevisiae; D014452:Ubiquitins; D044767:Ubiquitin-Protein Ligases; D008025:Ligases; D000071193:Autophagy-Related Protein 7