Kimura's disease in a teenage male: report of one case.
A 14-year-old boy gradually developed several subcutaneous masses over bilateral peri-auricular regions, neck, and both upper arms near the elbows over the past 2 years. The recent development of eyelid puffiness elicited his seeking medical attention. Hypereosinophilic syndrome was first considered due to the markedly elevated blood eosinophil count without other evidence of allergy or parasite infestation, but the absence of organ involvement made this diagnosis questionable. The histopathological investigation of the subcutaneous mass in the upper arm showed lymph node-like tissue with markedly reactive follicular hyperplasia and eosinophilic abscesses associated with granulomatous inflammation, thus leading to the final diagnosis of Kimura's disease. Oral prednisolone was prescribed successfully. This illness occurs mainly in young oriental males. We report this case to introduce it to pediatric clinicians as an important differential diagnostic entity in eosinophilia-associated diseases and reactive lymphadenopathy.
Huang
Y Y
YY
Department of Pediatrics, (Allergy, Immunology, and Rheumatology Section), Veterans General Hospital, Kaohsiung, Taiwan.
Huang
Y F
YF
Lee
C L
CL
Hsieh
K S
KS
Wang
J S
JS
Cheng
H H
HH
D000293:Adolescent; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male