[Function and dysfunction of the endothelium].
Endothelium is a multi-functional barrier separating blood from interstitium. It plays a role in coagulation, inflammation, angiogenesis and it has vasomotor functions. The endothelial dysfunction can be considered as an initial stage of atherosclerosis. Using morphological and biochemical methods it is possible to study the influence of cardiovascular risk factors on the vessels and the effect of therapeutic interventions. A short review of endothelial functions, endothelial dysfunction and its quantification methods is presented in this article.
Malík
J
J
III. interní klinika VFN a 1. LF UK, Praha.
Melenovský
V
V
Wichterle
D
D
D001777:Blood Coagulation; D004730:Endothelium, Vascular / Q000502:physiology* / Q000503:physiopathology; D006801:Humans; D018919:Neovascularization, Physiologic