pH-controlled inclusion and release of oxyanions by dendrimers bearing methyl orange moieties.
We report the synthesis of POPAM dendrimers, bearing up to 64 chromophores at their periphery. For these dendrimers, a radiotracer technique was used to study the liquid-liquid partition of pertechnetate and (14)C-labeled nucleotides in trichloromethane-aqueous systems. Inclusion and release of guest molecules can be controlled by changing the pH. The extraction efficacy increases with rising generation number.
Institut für Bioanorganische und Radiopharmazeutische Chemie, Forschungszentrum Rossendorf, 01314 Dresden, Germany.
H
H
Stephan
H
H
Spies
B
B
Johannsen
C
C
Kauffmann
F
F
Vögtle
D001391:Azo Compounds / Q000737:chemistry* / Q000378:metabolism*; D002725:Chloroform / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D009711:Nucleotides / Q000378:metabolism; D011073:Polyamines / Q000737:chemistry* / Q000378:metabolism*; D013670:Sodium Pertechnetate Tc 99m / Q000737:chemistry* / Q000378:metabolism*; D012997:Solvents
D001391:Azo Compounds; D009711:Nucleotides; D011073:Polyamines; D012997:Solvents; C100258:methyl orange; D002725:Chloroform; D013670:Sodium Pertechnetate Tc 99m