Quantification of cerebral blood flow by bolus tracking and artery spin tagging methods.
This study deals with perfusion quantification in healthy volunteers using two types of dynamic magnetic resonance imaging (MRI) methods. Absolute cerebral blood flow (CBF) measurements were performed in 11 subjects by applying both bolus tracking of exogenous contrast agent and non-invasive arterial spin labeling MRI techniques. Both methods produced CBF images with good tissue contrast and CBF values are in good agreement with literature data. The correlation between cerebral blood volume (CBV) and CBF is also discussed.
Lia
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Lucas MRS Center, Department of Radiology, Stanford University School of Medicine, CA 94305, USA. tie@s-word.stanford.edu
Guang Chen
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Ostergaard
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Hindmarsh
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Moseley
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D001158:Arteries / Q000033:anatomy & histology; D002138:Calibration; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000098:blood supply*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010477:Perfusion; D012039:Regional Blood Flow; D013113:Spin Labels
D013113:Spin Labels