Reversible renal failure after treatment with omeprazole.
Omeprazole is a proton pump inhibitor widely used in the treatment of gastro-esophageal reflux disease and peptic ulcer disease. In a 73-year-old man we describe renal failure due to acute interstitial nephritis after use of omeprazol during 4 months. Unexpected renal failure without signs of hydronephrosis should always provoke awareness of drug reaction, omeprazole being one of the possible drugs.
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Sint Franciscus Gasthuis, Department of Internal Medicine, Rotterdam, The Netherlands. aukepost@hotmail.com
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D058186:Acute Kidney Injury / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D000368:Aged; D004791:Enzyme Inhibitors / Q000009:adverse effects*; D005764:Gastroesophageal Reflux / Q000150:complications / Q000188:drug therapy; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D009853:Omeprazole / Q000009:adverse effects*; D020127:Recovery of Function / Q000187:drug effects; D016896:Treatment Outcome
D004791:Enzyme Inhibitors; D009853:Omeprazole