[Effects of SH-compounds on changes in the antioxidant enzyme activity in various tissues during acute pancreatitis].
In rats with experimental acute pancreatitis, activity of the antioxidant defense enzyme in pancreatic and liver tissues increases, while that in the blood erythrocytes decreases. Preliminary administration of SH-compounds, especially unithiol, favored an increase in the activity of superoxide dismutase, catalase, and glutathione peroxidaze.
Second Tashkent State Medical Institute, Republic of Uzbekistan.
R A
RA
Sabirova
F Kh
FKh
Inoiatova
O S
OS
Gapparov
D000208:Acute Disease; D000818:Animals; D002374:Catalase / Q000097:blood / Q000378:metabolism*; D003545:Cysteine / Q000494:pharmacology; D005979:Glutathione Peroxidase / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D008297:Male; D008715:Methionine / Q000494:pharmacology; D010179:Pancreas / Q000201:enzymology; D010195:Pancreatitis / Q000201:enzymology*; D051381:Rats; D013438:Sulfhydryl Compounds / Q000494:pharmacology*; D013482:Superoxide Dismutase / Q000097:blood / Q000378:metabolism*; D014494:Unithiol / Q000494:pharmacology
D013438:Sulfhydryl Compounds; D014494:Unithiol; D008715:Methionine; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D003545:Cysteine