[Glycyrrhizic Acid Reference Standard (Control 991) of National Institute of Health Sciences].
The raw material of glycyrrhizic acid examined for preparation of the "Glycyrrhizic Acid Reference Standard". The analytical data obtained were: UV spectrum: Lambda max, 251 nm; specific absorbance (E (1%) 1cm) in ethanol at 251 nm, 146; IR spectrum, specific absorptions at 1716,1656, 1215, and 1170 cm-1; and the spectrum of raw material was consistent with that of Standard (Control 941). Also, thin-layer chromatography, no impurities detected; high-performance liquid chromatography, three impurities detected. The amount of each impurity was estimated at less than 0.1%, and the total amount of impurities was less than 0.2%. Based on the above results, the candidate material was authorized as the Glycyrrhizic Acid Reference Standard (Control 991) of the National Institute of Health Sciences.
H
H
Saito
W
W
Kawaguchi
M
M
Iwata
K
K
Maekawa
T
T
Tanimoto
S
S
Okada
D019695:Glycyrrhizic Acid / Q000592:standards*; D006077:Government Agencies; D007564:Japan; D010602:Pharmacopoeias as Topic / Q000592:standards; D012015:Reference Standards
D019695:Glycyrrhizic Acid