Effect of vitamin "A" on free radical cascade in pregnancy induced hypertension.
The role of vitamin A therapy in pregnancy induced hypertension (P.I.H.) on free radical cascade was studied in P.I.H. patients of third trimester. It was found that vitamin A therapy causes statistically significant decrease in lipid peroxidation. However it has no effect on superoxide dismutase and catalase. This indicates that vitamin A acts as chain breaking antioxidant. The present study opens a future prospective of giving vitamin A for the prophylaxis of P.I.H.
Department of Biochemistry, King George's Medical College, Lucknow, India.
S
S
Pandey
R
R
Srivastava
S
S
Pandey
D
D
Mukerjee
S
S
Khattri
K
K
Shanker
D000328:Adult; D005260:Female; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000378:metabolism*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000378:metabolism*; D011507:Proteinuria / Q000188:drug therapy; D014801:Vitamin A / Q000494:pharmacology*
D005609:Free Radicals; D014801:Vitamin A