Increased need for medical interventions in infants with velocardiofacial (deletion 22q11) syndrome.
Ten of 12 patients diagnosed with deletion 22q11.2 in infancy required a total of 26 hospitalizations during their first year of life. After heart disease, feeding and respiratory problems were the most frequent reasons for intervention.
Division of Human Genetics and the Craniofacial Center, Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
R J
RJ
Hopkin
E K
EK
Schorry
M
M
Bofinger
H M
HM
Saal
D000015:Abnormalities, Multiple / Q000453:epidemiology / Q000235:genetics / Q000628:therapy*; D002872:Chromosome Deletion; D002892:Chromosomes, Human, Pair 22; D019468:Disease Management; D005247:Feeding Behavior; D005260:Female; D006330:Heart Defects, Congenital / Q000453:epidemiology / Q000235:genetics / Q000628:therapy*; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009820:Ohio / Q000453:epidemiology; D012141:Respiratory Tract Infections / Q000453:epidemiology; D012189:Retrospective Studies; D013391:Sucking Behavior