Signaling networks linking integrins and rho family GTPases.
Integrins and Rho family GTPases function coordinately to mediate adhesion-dependent events in cells. Recently, it has also become apparent that integrins regulate Rho GTPases and vice versa. Integrins and GTPases might therefore be organized into complex signaling cascades that regulate cell behavior.
Schwartz
M A
MA
Dept of Vascular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. schwartz@scripps.edu
Shattil
S J
SJ
D000818:Animals; D002448:Cell Adhesion / Q000502:physiology; D005109:Extracellular Matrix; D016023:Integrins / Q000378:metabolism*; D010770:Phosphotransferases / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*; D020741:rho GTP-Binding Proteins / Q000378:metabolism*
D016023:Integrins; D010770:Phosphotransferases; D020741:rho GTP-Binding Proteins