[Incidental diagnosis of seminoma in male infertility: report of a clinical case].
The aims of the study were to evaluate the association between male infertility and risk of developing testis cancer and to establish guidelines for the early diagnosis of testis neoplasia in subfertile men. 32-year-old infertile man. The patient underwent random testicular biopsy to establish the exact cause of infertility. An incidental diagnosis of seminoma was made and the patient then underwent right testis excision. Anatomopathologic macroscopic examination revealed two nodules, the sizes of which were 0.8 x 0.4 and 0.3 x 0.2 cm, respectively. Histologic examination confirmed the diagnosis of typical seminoma, pT1, with copious lymphocytic struma infiltration. There appears to be a correlation between male infertility and occurrence of seminoma. Diagnosis of testis cancer is often incidental and sometimes occurs in men undergoing testicular biopsy to investigate infertility. Since the biopsy was not specifically targeted in our case, the diagnosis of seminoma was casual. This suggests the need for a careful follow-up, including testicular ultrasonography as a screening test to achieve an early diagnosis of testis cancer in all infertile men, because of their higher risk of developing testis cancer than the normal population.
Dipartimento di Fisiopatologia Medica, Policlinico Umberto I, Università degli Studi La Sapienza, Roma.
F
F
La Torre
G
G
Spera
M
M
Arizzi
L
L
Bonanno
M
M
Otti
E
E
Ruggeri
D
D
Taglienti
D000328:Adult; D006801:Humans; D007248:Infertility, Male / Q000209:etiology*; D008297:Male; D018239:Seminoma / Q000150:complications* / Q000175:diagnosis*; D013736:Testicular Neoplasms / Q000150:complications* / Q000175:diagnosis*