[Clinical course of isolated larval infestation of orbit in children].
Clinical course of an isolated infestation of orbital tissues by larvae of helminths parasitizing in dogs (Toxocara canis) has been followed up in 5 patients aged 6-13 years. The process ran a wave-like course for 3-8 months and was characterized by cyclic inflammatory changes in the orbit, presenting by toxic allergic tenonitis, regional lymphadenitis, optic nerve perineuritis with formation of parasitic granuloma detected by computer-aided rhoentgenotomography of the orbit. No clinical or laboratory signs of common inflammatory and allergic reaction in the presence of Toxocara antigen sensitization were observed in any case, which was confirmed by detection of specific antibodies (IgG and IgE). Specific therapy with anti-nematode drug albendazol was effective.
L A
LA
Dubovskaia
N I
NI
Tumol'skaia
N I
NI
Sidorenko
G I
GI
Kotiasheva
E D
ED
Odoshashvili
A V
AV
Gorbunov
D000293:Adolescent; D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D000909:Antibodies, Helminth / Q000032:analysis; D002648:Child; D003937:Diagnosis, Differential; D015822:Eye Infections, Parasitic / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology; D005260:Female; D006801:Humans; D007816:Larva Migrans, Visceral / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D008297:Male; D009915:Orbit / Q000469:parasitology*; D009916:Orbital Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D012189:Retrospective Studies; D017166:Toxocara canis / Q000276:immunology / Q000302:isolation & purification
D000871:Anthelmintics; D000909:Antibodies, Helminth; D015766:Albendazole