Mycophenolic acid in silage.
We examined 233 silage samples and found that molds were present in 206 samples with counts between 1 x 10(3) and 8.9 x 10(7) (mean, 4.7 x 10(6)) CFU/g. Mycophenolic acid, a metabolite of Penicillium roqueforti, was detected by liquid chromatography-mass spectrometry in 74 (32%) of these samples at levels ranging from 20 to 35,000 (mean, 1,400) microg/kg. This compound has well-known immunosuppressive properties, so feeding with contaminated silage may promote the development of infectious diseases in livestock.
Institute of Animal Hygiene, Faculty of Agriculture and Horticulture, Technische Universität München, 85354 Freising-Weihenstephan, Federal Republic of Germany.
I
I
Schneweis
K
K
Meyer
S
S
Hörmansdorfer
J
J
Bauer
D002853:Chromatography, Liquid; D015169:Colony Count, Microbial; D013058:Mass Spectrometry; D009173:Mycophenolic Acid / Q000032:analysis* / Q000378:metabolism; D010407:Penicillium / Q000302:isolation & purification* / Q000378:metabolism; D006109:Poaceae; D015203:Reproducibility of Results; D012820:Silage / Q000382:microbiology*; D003313:Zea mays
D009173:Mycophenolic Acid