[Scintigraphy with 99mTc-HMPAO-marked leukocytes and abdominal tumors: clinical interpretation of scintigraphy results].
The 99mTc-HMAPAO-labelled leucocyte scan is a widely employed diagnostic tool in the assessment of inflammatory and infective diseases. Nevertheless, leucocytes accumulation in neoplastic lesions has been reported. In the present study, aimed at the exploration of the abdomen and performed on 62 patients, positive scintigraphic findings were obtained in 66.6% (4/6) of the neoplasms and in 6.45% (4/62) of the studied cases. These scintigraphic results, even if they have to be considered as false positive cases, effectively reflect histopathologic changes present in the neoplastic tissue. On the basis of the obtained results, leucocytes accumulation in abdominal malignancies is probably due to the presence of necrosis and ulceration and to the resulting infection of the tumour.
Dipartimento di Medicina Sperimentale e Patologia, Universita degli Studi "La Sapienza", Roma.
A M
AM
Filippis
G
G
Petrilli
V
V
Fiore
A
A
D'Agostini
L
L
Manini
G
G
Neri
A
A
Filippini
Y
Y
Waly
L
L
Giacomelli
M
M
Liberatore
D000008:Abdominal Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015994:Incidence; D007962:Leukocytes; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D019690:Technetium Tc 99m Exametazime
D019275:Radiopharmaceuticals; D019690:Technetium Tc 99m Exametazime