Antioxidant activity of phenylethanoid glycosides from Brandisia hancei.
Brandisia hancei is a medicinal herb in China. The ethanol extract of this plant and four phenylethanoid glycosides, acteoside (1), 2'-acetylacteoside (2), poliumoside (3) and brandioside (4), isolated from it were shown to have inhibitory effects on free radical-induced hemolysis of red blood cells and free radical scavenging activities in vitro. Brandioside (4) and poliumoside (3) showed stronger antioxidant effect than acteoside (1), 2'-acetylacteoside (2) and trolox.
Institute of Chinese Medicine and Department of Biology, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, PR China.
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D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005419:Flavonoids; D006027:Glycosides / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects; D008516:Medicine, Chinese Traditional; D010636:Phenols / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal; D011108:Polymers / Q000494:pharmacology*; D059808:Polyphenols; D051381:Rats
D000975:Antioxidants; D005419:Flavonoids; D006027:Glycosides; D010636:Phenols; D010936:Plant Extracts; D011108:Polymers; D059808:Polyphenols