Synthesis and biological activity of 4'-methoxy derivatives of abscisic acid.
Replacing the 4'-carbonyl group of abscisic acid with a methoxy group does not affect the abscisic acid (ABA)-like activities of the product in barley aleurone protoplasts, although the reduction of ABA to 4'-hydroxyl derivatives significantly reduces the ABA-like activity of the products. This suggests that methoxy derivatives of abscisic acid might be used to produce probes for ABA binding proteins.
RIKEN (The Institute of Physical and Chemical Research), Wako, Saitama, Japan. tasami@postman.riken.gp.jp
T
T
Asami
Y K
YK
Min
T
T
Nakano
T
T
Matsuyama
N
N
Murofushi
I
I
Yamaguchi
S
S
Yoshida
D000040:Abscisic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D015195:Drug Design; D004790:Enzyme Induction / Q000187:drug effects; D001467:Hordeum / Q000201:enzymology; D015394:Molecular Structure; D010937:Plant Growth Regulators / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011523:Protoplasts / Q000187:drug effects / Q000201:enzymology; D013329:Structure-Activity Relationship; D000516:alpha-Amylases / Q000096:biosynthesis*
D010937:Plant Growth Regulators; D000040:Abscisic Acid; D000516:alpha-Amylases