Pulmonary migratory infiltrates and pachypleuritis in a patient with Crohn's disease.
Crohn's disease can be associated with several respiratory manifestations. We report here a case of pulmonary migratory infiltrates associated with bilateral pleural thickening and peripheral eosinophilia. The histopathological findings show an association of necrotizing nodules, eosinophilic infiltration in the non-abscessed lung tissue, areas of non-caseating epithelioid granulomas, and an extensive pleural fibrosis. The different histopathological findings are detailed and the responsibility of either Crohn's disease or treatment by mesalazine is discussed.
Faller
M
M
Service de Pneumologie, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Gasser
B
B
Massard
G
G
Pauli
G
G
Quoix
E
E
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003424:Crohn Disease / Q000150:complications* / Q000188:drug therapy; D004802:Eosinophilia / Q000150:complications; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D019804:Mesalamine / Q000627:therapeutic use; D010998:Pleurisy / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed
D000894:Anti-Inflammatory Agents, Non-Steroidal; D019804:Mesalamine