Achievements and future of chemotherapy.
Although surgery and radiotherapy result in a cure in 40% of all cancer patients, the remaining 60% of the patients die as a result of metastatic disease. For those patients cancer has to be considered as a systemic disease and cure from cancer will likely come from some type of systemic treatment. This article gives a brief overview of the achievements in the development of chemotherapy over the last 50 years and the new potential targets for further drug development.
Department of Medical Oncology, Rotterdam Cancer Institute (Daniel den Hoed Kliniek) and University Hospital, Groene Hilledijk 301, 3075 EA, Rotterdam, The Netherlands. verweij@onch.azr.nl
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Verweij
M J
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de Jonge
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D011788:Quality of Life
D000970:Antineoplastic Agents