Orbital involvement as the initial manifestation of sarcoidosis: magnetic resonance imaging findings.
A 74-year-old man had diplopia, painful right ophthalmoplegia, proptosis, conjunctival injection, and facial skin lesions. Magnetic resonance imaging (MRI) revealed infiltration of the right intraorbital adipose tissue. Lesions were mixed low- and high-signal on T2-weighted images and enhanced on fat-suppressed T1-weighted postcontrast images. A skin biopsy revealed numerous noncaseating granulomas consistent with sarcoidosis. Treatment with corticosteroids and chlorambucil led to a full clinical recovery. Sarcoidosis should be considered in the evaluation of orbital pseudotumor in elderly patients, even if no systemic manifestations of sarcoidosis are present.
Shaikh
Z A
ZA
Department of Neurology, University at Buffalo, State University of New York, School of Medicine and Biomedical Sciences, Buffalo, NY, USA.
Bakshi
R
R
Greenberg
S J
SJ
Fine
E J
EJ
Shatla
A
A
Lincoff
N S
NS
D000368:Aged; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009915:Orbit / Q000473:pathology; D009916:Orbital Diseases / Q000175:diagnosis*; D012507:Sarcoidosis / Q000175:diagnosis*