Diffusion- and perfusion-weighted MRI in a patient with a prolonged reversible ischaemic neurological deficit.
We report acute and follow-up diffusion- and perfusion-weighted MRI (DWI, PWI) findings in a patient with a prolonged reversible ischaemic neurological deficit. PWI 12 h after the patient was last seen to be without symptoms revealed a large perfusion deficit in the left posterior MCA territory with a relatively inconspicuous and much smaller abnormality on DWI. Follow-up showed resolution of abnormalities on both DWI and PWI, and conventional MRI was normal, apart from a very slight abnormality, visible only on FLAIR images, at the centre of the initially DWI-positive region. These findings demonstrate the utility of PWI when be used in combination with DWI to investigate the pathophysiology of transient ischemic syndromes.
Department of Neurology (ZNN 95-1), Goethe-Universität, Frankfurt, Germany. tnh@rz.uni-frankfurt.de
T
T
Neumann-Haefelin
H J
HJ
Wittsack
F
F
Wenserski
T Q
TQ
Li
M E
ME
Moseley
M
M
Siebler
H J
HJ
Freund
D000368:Aged; D001041:Aphasia, Wernicke / Q000175:diagnosis; D002540:Cerebral Cortex / Q000098:blood supply / Q000473:pathology; D004058:Diffusion; D004292:Dominance, Cerebral / Q000502:physiology; D005500:Follow-Up Studies; D006801:Humans; D007089:Image Enhancement; D002546:Ischemic Attack, Transient / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination; D010291:Paresis / Q000175:diagnosis; D020769:Posterior Cerebral Artery / Q000473:pathology; D012039:Regional Blood Flow / Q000502:physiology