Perforated gastric ulcer complicating corticosteroid therapy in acute rheumatic fever.
We report an 11-year-old boy with acute rheumatic fever who presented with gastric perforation while treated with corticosteroids (CS). He had been treated initially with acetylsalicylic acid for 11 days, CS replaced the treatment with acetylsalicylic acid due to deterioration of carditis. The possible pathogenesis is discussed.
Department of Paediatrics, Bikur Cholim General Hospital, Jerusalem, Israel.
A
A
Klar
J
J
Moise
A
A
Brand
D
D
Seror
H
H
Hurvitz
D000305:Adrenal Cortex Hormones / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D005500:Follow-Up Studies; D006801:Humans; D007813:Laparotomy; D008297:Male; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000188:drug therapy; D010439:Peptic Ulcer Perforation / Q000139:chemically induced* / Q000601:surgery; D012213:Rheumatic Fever / Q000175:diagnosis / Q000188:drug therapy*; D012214:Rheumatic Heart Disease / Q000175:diagnosis / Q000188:drug therapy; D013276:Stomach Ulcer / Q000139:chemically induced*
D000305:Adrenal Cortex Hormones