Intravitreal antiviral injections as adjunctive therapy in the management of immunocompetent patients with necrotizing herpetic retinopathy.
OBJECTIVE
To report the use of intravitreal antiviral injections as adjunctive therapy in the management of three immunocompetent patients with necrotizing herpetic retinopathy.


METHODS
Case series.


RESULTS
Three patients with necrotizing herpetic retinopathy received intravitreal antiviral injections for treatment of progressive retinitis, despite standard intravenous acyclovir therapy. The retinitis resolved and visual acuity improved after a minimum of 6 months of follow-up in each case.


CONCLUSIONS
Intravitreal antiviral injections may be a safe and efficacious adjunctive therapy in the management of patients with necrotizing herpetic retinopathy.
Bascom Palmer Eye Institute, Miami, Florida 33136, USA.
K K
KK
Luu
I U
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Scott
N A
NA
Chaudhry
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Verm
J L
JL
Davis
D000212:Acyclovir / Q000627:therapeutic use*; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D004359:Drug Therapy, Combination; D015828:Eye Infections, Viral / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use*; D006561:Herpes Simplex / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D006801:Humans; D007121:Immunocompetence; D007267:Injections; D008297:Male; D008875:Middle Aged; D015882:Retinal Necrosis Syndrome, Acute / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D014792:Visual Acuity; D014822:Vitreous Body
D000998:Antiviral Agents; D015774:Ganciclovir; D000212:Acyclovir