Properties of various Rho1 mutant alleles of Cryptococcus neoformans.
The RHO1 homologue of Cryptococcus neoformans complemented Saccharomyces cerevisiae rho1 mutations. The results of overexpression and site-specific mutagenesis of CnRHO1 in C. neoformans and S. cerevisiae indicated that although CnRHO1 could functionally substitute for the RHO1 gene of S. cerevisiae, mutants of cnrho1 manifested unique features in certain aspects.
Chang
Y C
YC
Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. yc3z@nih.gov
Penoyer
L A
LA
D000483:Alleles; D001483:Base Sequence; D003001:Cloning, Molecular; D003455:Cryptococcus neoformans / Q000201:enzymology* / Q000235:genetics; D004271:DNA, Fungal; D015870:Gene Expression; D005800:Genes, Fungal; D005964:Glucosyltransferases / Q000378:metabolism; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D012441:Saccharomyces cerevisiae / Q000235:genetics; D029701:Saccharomyces cerevisiae Proteins; D013696:Temperature; D020741:rho GTP-Binding Proteins / Q000235:genetics* / Q000502:physiology
D004271:DNA, Fungal; D029701:Saccharomyces cerevisiae Proteins; D005964:Glucosyltransferases; C040232:glucan synthase; C051302:RHO1 protein, S cerevisiae; D020741:rho GTP-Binding Proteins