[Choroid plexus carcinoma: report of 15 cases].
Choroid plexus carcinoma (CPC) are rare central nervous system tumours derived from choroid plexus epithelium, affecting mainly children under 3 years of age. We present a clinical, epidemiological and histopathological study of 15 cases of CPC. Ten patients were male. Age ranged from 4 months to 21 years (mean=3,4). The lateral ventricles were affected in 73,3% of cases. Main symptom were: hydrocephalus (62.5%), intracranial hypertension (25%) and convulsion (12.5%). The patients were treated by surgery with partial resection in 75% of cases and total resection in 25%. There was one death due to surgical complication, 85.7% of patients had recurrence of tumours with mean survival rate of 13.6% months after diagnosis. Only one patient remain alive 5 years after initial treatment. These results support the poor prognosis and high mortality rate of CPC.
Seção de Microscopia Eletrônica e Neuropatologia, Serviço de Anatomia Patológica, Hospital de Clínicas, Universidade Federal do Paraná.
L F
LF
Bleggi-Torres
L A
LA
Urban
A
A
Antoniuk
P
P
Carboni
R
R
Ramina
E S
ES
Gugelmin
D000328:Adult; D002277:Carcinoma / Q000401:mortality / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D016545:Choroid Plexus Neoplasms / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011379:Prognosis; D015996:Survival Rate