[Multisystem disease caused by BCG imitating miliary tuberculosis].
As the prevalence of tuberculosis is on the rise in western countries, we present a 79-year-old man who developed a pulmonary tuberculosis-like syndrome following immunotherapy with BCG for carcinoma of the urinary bladder. The symptoms subsided following 3-drug antitubercular treatment, and the addition of steroids following negative cultures for Mycobacterium tuberculosis. The course of this disease, named BCG-osis, is much more favorable than miliary tuberculosis, even with milder treatment. It is important to keep in mind this phenomenon now that there is increasing treatment of cancers with BCG.
Tsikonov
I
I
Dept. of Medicine A, Bnai Zion Medical Center, Technion, Haifa.
Yeshurun
D
D
Naschitz
J E
JE
D000276:Adjuvants, Immunologic / Q000009:adverse effects*; D000368:Aged; D001500:BCG Vaccine / Q000009:adverse effects*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D009164:Mycobacterium Infections / Q000175:diagnosis / Q000209:etiology*; D014391:Tuberculosis, Miliary / Q000175:diagnosis; D001749:Urinary Bladder Neoplasms / Q000628:therapy*
D000276:Adjuvants, Immunologic; D001500:BCG Vaccine