Juvenile rheumatoid arthritis presented with thrombocytopenia.
Leukopenia and thrombocytopenia are rare findings in systemic onset juvenile rheumatoid arthritis (S-JRA), and if present, bone marrow (BM) examination is necessary to exclude malignant diseases. We report here a 13.5-year-old boy with S-JRA who had severe thrombocytopenia and mild leukopenia, without arthritis, at the onset of the disease. BM was hypercellular with increased numbers of myeloid precursors and megakaryocytes. After treatment with acetylsalicylic acid, leukocyte and platelet counts returned to normal levels, and after two months chronic arthritis developed.
Department of Pediatrics, Harran University Faculty of Medicine, Sanliurfa, Turkey.
A
A
Koç
M
M
Kösecik
M M
MM
Tatli
A
A
Ataş
H H
HH
Emiroğlu
D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000150:complications* / Q000188:drug therapy; D001241:Aspirin / Q000627:therapeutic use; D001856:Bone Marrow Examination; D006801:Humans; D007970:Leukopenia / Q000150:complications*; D008297:Male; D013921:Thrombocytopenia / Q000150:complications*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin