Costimulatory signal blockade by anti-CD2 monoclonal antibody in combination with 15-deoxyspergualin prolongs concordant xenograft survival.
Department of Thoracic and Cardiovascular Surgery, Niigata University School of Medicine, Niigata, Japan. haga@med.niigata-u.ac.jp
M
M
Haga
H
H
Hirahara
M
M
Tsuchida
T
T
Watanabe
M
M
Takekubo
J
J
Hayashi
D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D018801:CD2 Antigens / Q000276:immunology / Q000502:physiology*; D006085:Graft Survival / Q000187:drug effects / Q000276:immunology*; D006146:Guanidines / Q000494:pharmacology*; D016027:Heart Transplantation / Q000276:immunology* / Q000473:pathology; D007165:Immunosuppression Therapy / Q000379:methods; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D051379:Mice; D008807:Mice, Inbred BALB C; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew; D013997:Time Factors; D014183:Transplantation, Heterologous / Q000276:immunology* / Q000473:pathology
D000911:Antibodies, Monoclonal; D018801:CD2 Antigens; D006146:Guanidines; D007166:Immunosuppressive Agents; C037258:gusperimus