Liver lesions: intermittent second-harmonic gray-scale US can increase conspicuity with microbubble contrast material-early experience.
The authors investigated the effect of intermittent second-harmonic gray-scale (ISHGS) ultrasonography (US) with SH U 508A microbubbles on the conspicuity of focal liver lesions. Twenty-three patients were included in the study. Images were analyzed subjectively and quantitatively. Objective lesion conspicuity was increased. In 12 of the 15 patients with liver malignancy, gray-scale defects were seen in previously unsuspected areas. ISHGS US may improve the sensitivity of US for liver lesions.
Heckemann
R A
RA
Department of Imaging, Hammersmith Hospital, Du Cane Road, London W12 0HS, United Kingdom.
Cosgrove
D O
DO
Blomley
M J
MJ
Eckersley
R J
RJ
Harvey
C J
CJ
Mine
Y
Y
D000328:Adult; D000368:Aged; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging; D002277:Carcinoma / Q000000981:diagnostic imaging; D003287:Contrast Media / Q000008:administration & dosage; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000000981:diagnostic imaging; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007262:Infusions, Intravenous; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D019047:Phantoms, Imaging; D011134:Polysaccharides / Q000008:administration & dosage; D012680:Sensitivity and Specificity; D014465:Ultrasonics; D014463:Ultrasonography; D014743:Videotape Recording
D003287:Contrast Media; D011134:Polysaccharides; C059891:SHU 508