[Multiple sclerosis: descriptive study of its clinical forms in 302 cases].
Multiple sclerosis (MS) is one of the most common causes of chronic neurologic disability in young adults. We evaluate, through retrospective study, the epidemiological characteristics, the manifestations ways, the clinical manifestations, the evolution and the level of physical disability of MS in 302 patients. The average patients age was 37.7 and the relation between genders was 3.13F:1M. The average age at the beginning of MS was 29.6; 283 patients were white (94%), 15 patients were black (5%) and 4 patients were yellow; 220 patients (72%) presented relapsing-remmiting clinical form; 82 patients (28%) presented the progressive form (50% secondary form and 50% primarily progressive form). The most common initial symptoms were sensitive (31.7%) and optical (26.8%). The most common evolutive symptoms were pyramidal (72.5%) and of the spinal cord (64.9%). The average of the final EDSS was 3.37 and final NRS was 85.17. The index of the annual outbreak was 0.45. Our findings coincide to the ones in the worldwide literature, however it is important to point out that 60 patients (19.8%) presented benign MS of prognostic value.
Moreira
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Centro de Atendimento e Tratamento da Esclerose Múltipla, Clínica Neurológica, Faculdade de Ciências Médicas, Santa Casa de Misericórdia de São Paulo, Brazil. neurologia@santacasasp.org.br
Felipe
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Mendes
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Tilbery
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CP
D000328:Adult; D017668:Age of Onset; D005260:Female; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications / Q000453:epidemiology*; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000150:complications / Q000453:epidemiology; D011379:Prognosis; D012189:Retrospective Studies