Medical management of Aspergillus flavus endocarditis.
An 11-year-old boy underwent a matched unrelated bone marrow transplant for refractory acute myeloid leukemia. He developed invasive aspergillus pneumonia and endocarditis post-transplant. The fungal endocarditis was successfully eradicated with liposomal amphotericin at the dose of 10 mg/kg/day. Surgical intervention was not required and no serious side effects of liposomal amphotericin were observed at this dose.
Department of Paediatric Haematology and Oncology, Royal London Hospital, United Kingdom.
K
K
Rao
V
V
Saha
D000666:Amphotericin B / Q000008:administration & dosage; D001228:Aspergillosis; D001231:Aspergillus flavus; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D002648:Child; D019468:Disease Management; D004696:Endocarditis / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008081:Liposomes / Q000627:therapeutic use; D008297:Male
D008081:Liposomes; D000666:Amphotericin B