Multi-layered regulation of courtship behaviour.
The fruitless gene governs courtship in male, but not female, Drosophila, yet it is expressed and specifically spliced in the brains of both sexes. New experiments reveal that a splice-recognition site retained in the mature message in females provides the basis for sex-specific translational repression.
Wasserman
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D017398:Alternative Splicing / Q000235:genetics; D000818:Animals; D003380:Courtship; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D008297:Male; D009132:Muscles / Q000378:metabolism; D009154:Mutation; D009419:Nerve Tissue Proteins / Q000096:biosynthesis* / Q000235:genetics*; D009687:Nuclear Proteins / Q000378:metabolism; D016366:Open Reading Frames / Q000235:genetics; D014176:Protein Biosynthesis / Q000235:genetics*; D012045:Regulatory Sequences, Nucleic Acid / Q000235:genetics; D012261:Ribonucleoproteins / Q000378:metabolism; D012727:Sex Characteristics; D014157:Transcription Factors / Q000096:biosynthesis* / Q000235:genetics*
D029721:Drosophila Proteins; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; D012261:Ribonucleoproteins; C097162:Tra protein, Drosophila; D014157:Transcription Factors; C103226:fru protein, Drosophila; C066174:tra2 protein, Drosophila