Stalk dynamics and lipid flow upon membrane hemifusion.
A hydrodynamic theory describing the stalk dynamics and lipid flows upon BLM hemifusion was developed. The value of intermonolayer viscosity, etar, for membranes formed from azolectin mixed with lysophosphatidylcholine (7.10(-4) mg/ml) in n-decane, etar approximately 10(-9) g/s, was determined from comparison of the theoretical calculations and literature data. For membranes formed in squalene, the values etar approximately 10(-7) g/s for phosphatidylethanolamine and etar approximately 2-10(-7) g/s for azolectin were obtained. The calculated values are close to the published results of independent experiments which shows that the developed theory describes well the stalk growth and lipid flow.
Kumenko
D A
DA
Frumkin Institute of Electrochemistry, Russian Academy of Sciences, Moscow.
Kuzmin
P I
PI
Chizmadzhev
Y A
YA
D002459:Cell Fusion; D002462:Cell Membrane / Q000378:metabolism* / Q000648:ultrastructure; D004734:Energy Metabolism / Q000502:physiology; D006874:Hydrostatic Pressure; D008563:Membrane Lipids / Q000378:metabolism*; D008954:Models, Biological; D017711:Nonlinear Dynamics
D008563:Membrane Lipids