GBV-C/HGV genotypes: proposed nomenclature for genotypes 1-5.
The GB virus-C and hepatitis G virus (GBV-C/HGV) are variants of the same flavivirus. This proposal attempts to clarify the conflicting nomenclature for GBV-C/HGV genotypes. The first three genotypes described were genotype 1 (West Africa); genotype 2 (US/Europe) and genotype 3 (Asia). Subsequently, two groups published data from South Africa and Southeast Asia both stating the presence of a novel "4th genotype." These isolates are distinct phylogenetically. It is proposed that the nomenclature for genotypes 1-3 remains as per previous publications, and that the Southeast Asian isolates be known as genotype 4, and the South African isolates as genotype 5.
Tucker
T J
TJ
Department of Medical Microbiology/SAIMR and Medicine, University of Cape Town, South Africa. tim@curie.uct.ac.za
Smuts
H E
HE
D004279:DNA, Viral / Q000235:genetics*; D018067:Flaviviridae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D005838:Genotype; D005843:Geography; D006801:Humans; D010802:Phylogeny
D004279:DNA, Viral