Sonic detection system for cervical and intracranial vascular disease.
A sonic analysis system was developed for the detection of cervical and intracranial vascular disease (CVD). In this study, sound signals detected through the patient's forehead were analyzed using a short-time Fourier transformation method, and data were evaluated according to the intensity of spectra. A total of 49 patients with CVD and 34 control subjects were studied and classified into four grades according to the intensity of the spectra. The true positive rate was 83.7% in patients with CVD, and the true negative rate was 94.1% in the control group. The sensitivity and specificity of this analysis system were 83.7% and 5.9%, respectively. The true positive rates for cerebral stenosis/occlusion, cerebral aneurysm, and arteriovenous malformation/fistula were 85.7%, 73.7%, and 100%, respectively. The future goal is clinical application as a mass-screening test for brain disease. This system shows potential for this purpose, and further development will continue.
Department of Neurosurgery, Iwate Medical University, Morioka, Japan.
M
M
Abe
Y
Y
Otawara
M
M
Suzuki
N
N
Tomitsuka
A
A
Ogawa
S
S
Hongo
M
M
Abe
D000162:Acoustics / Q000295:instrumentation; D000293:Adolescent; D000328:Adult; D000368:Aged; D001164:Arteriovenous Fistula / Q000175:diagnosis; D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis; D008875:Middle Aged; D009333:Neck / Q000098:blood supply*; D012016:Reference Values; D014652:Vascular Diseases / Q000175:diagnosis*