Fractals and cancer.
Recent studies have shown that fractal geometry, a vocabulary of irregular shapes, can be useful for describing the pathological architecture of tumors and, perhaps more surprisingly, for yielding insights into the mechanisms of tumor growth and angiogenesis that complement those obtained by modern molecular methods. This article outlines the basic methods of fractal geometry and discusses the value and limitations of applying this new tool to cancer research.
Department of Mechanical Engineering, Bucknell University, Lewisburg, Pennsylvania 17837, USA.
J W
JW
Baish
R K
RK
Jain
D000465:Algorithms; D016503:Drug Delivery Systems; D017709:Fractals; D006801:Humans; D000860:Hypoxia; D008954:Models, Biological; D008962:Models, Theoretical; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology*; D009389:Neovascularization, Pathologic