Primary spinal germinoma in a patient with concomitant Klinefelter's syndrome.
It is known that patients with Klinefelter's syndrome are inclined to develop concomitant malignant tumours, as well as extragonadal germ cell tumours. The association of a primary spinal germinoma in a patient with Klinefelter's syndrome is reported for the first time, and the coincidence of elevated gonadotropin levels and oncogenesis is discussed.
Department of Neurosurgery & Radiology, University of Erlangen-Nürnberg, Germany. ganslandt@neurochir.med.uni-erlangen.de
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O
Ganslandt
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M
Buchfelder
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GG
Grabenbauer
D000328:Adult; D003131:Combined Modality Therapy; D018237:Germinoma / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007713:Klinefelter Syndrome / Q000150:complications* / Q000175:diagnosis; D008297:Male; D013120:Spinal Cord Neoplasms / Q000209:etiology* / Q000628:therapy