[The role of capsule formation in Burkholderia mallei for its persistence in vivo].
When studied in vivo (in guinea pigs) with the use of electron microscopy, B. mallei (strains C-5, 10230) were found to form a capsule. In the subacute course of infection, the encapsulated forms of B. mallei parasitized mainly in the cells of the system of mononuclear phagocytes in the liver, the spleen and the lungs. The capsule formed by B. mallei was shown to be one of the factors facilitating its persistence in the body.
Research Institute for Plague Control, Volgograd, Russia.
S F
SF
Popov
N G
NG
Tikhonov
N N
NN
Piven'
V Ia
VIa
Kurilov
I P
IP
Dement'ev
D000208:Acute Disease; D000818:Animals; D016667:Bacterial Capsules / Q000096:biosynthesis* / Q000648:ultrastructure; D019117:Burkholderia / Q000472:pathogenicity* / Q000648:ultrastructure; D005896:Glanders / Q000382:microbiology / Q000473:pathology; D006168:Guinea Pigs; D008099:Liver / Q000382:microbiology / Q000648:ultrastructure; D008168:Lung / Q000382:microbiology / Q000648:ultrastructure; D008854:Microscopy, Electron; D010586:Phagocytes / Q000382:microbiology / Q000648:ultrastructure; D013154:Spleen / Q000382:microbiology / Q000648:ultrastructure