[The heat-shock reaction is disturbed in a Drosophila virilis strain incapable of a neurohormonal stress reaction].
Cellular stress response was investigated in two lines of D. virilis: wild type and line with disturbed neurohormonal stress-reaction. Analysis of proteins, synthesized in salivary glands of larvae of both lines under heat stress, revealed malfunction in heat shock reaction of mutant specimen. This malfunction expresses in decreased level of heat shock protein synthesis. Analysis of electrophoretic spectra of proteins from homogenates of imagoes of both lines maintained under normal conditions and those exposed to heat (38 degrees C, 60 min.) revealed correlation between protein spectrum and physiological state of the organism. Interlinear differences by proteins spectra in normal condition, controlled by a single gene (or by block of closely linked genes), were found. The question if there is a common genetic control for the neurohormonal stress-reaction and cellular stress response is discussed.
Vasenkova
I A
IA
Khlebodarova
T M
TM
Sukhanova
M Zh
MZh
Gruntenko
N E
NE
Grenbek
L G
LG
Raushenbakh
I Iu
IIu
D000818:Animals; D004330:Drosophila / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods; D005260:Female; D006360:Heat-Shock Proteins / Q000032:analysis / Q000096:biosynthesis; D018869:Heat-Shock Response / Q000235:genetics / Q000502:physiology*; D007814:Larva; D009154:Mutation / Q000235:genetics / Q000502:physiology; D018377:Neurotransmitter Agents / Q000502:physiology*; D013312:Stress, Physiological / Q000235:genetics / Q000503:physiopathology*; D013696:Temperature; D013997:Time Factors
D006360:Heat-Shock Proteins; D018377:Neurotransmitter Agents