[Genetic factors predisposing to occupational fluorosis].
Having analyzed a total amount of all systems, the authors specified the most important genetic markers predisposing to chronic flour intoxication: the patients demonstrated higher frequency of ACP1*A and PGM1*1-alleles, phenotypes of acid phosphatase AA, of phosphoglucomutase 1+1+ and 2+2+, of dry cerumen consistence--d. The results could help to improve criteria of occupational selection and to specify practical recommendations on prophylaxis of chronic fluor intoxication.
Makarov
S V
SV
Spitsyn
V A
VA
Kravchuk
O I
OI
D000328:Adult; D002571:Cerumen / Q000737:chemistry; D002908:Chronic Disease; D005260:Female; D005458:Fluoride Poisoning / Q000453:epidemiology* / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology* / Q000235:genetics*; D010641:Phenotype; D010733:Phosphoglucomutase / Q000235:genetics; D010744:Phosphoric Monoester Hydrolases / Q000235:genetics
D010744:Phosphoric Monoester Hydrolases; D010733:Phosphoglucomutase