Thrombotic thrombocytopenic purpura in pulmonary-renal syndromes.
Thrombotic thrombocytopenic purpura pathologically consists of a thrombotic microangiopathy that classically spares lung tissues. We describe a case of TTP that presented as a pulmonary-renal syndrome. In reviewing the international literature, pulmonary involvement is not as rare as once was thought, and the diagnosis of TTP should be considered in the differential diagnosis of pulmonary-renal syndromes.
Hematology/Oncology Unit, Department of Medicine, The University of Rochester Medical Center, Rochester, New York [corrected], USA. n.panoskaltsis@ic.ac.uk
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N
Panoskaltsis
M P
MP
Derman
I
I
Perillo
J K
JK
Brennan
D003937:Diagnosis, Differential; D004417:Dyspnea / Q000150:complications; D017809:Fatal Outcome; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007674:Kidney Diseases / Q000150:complications*; D008171:Lung Diseases / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011697:Purpura, Thrombotic Thrombocytopenic / Q000150:complications* / Q000175:diagnosis; D006435:Renal Dialysis; D013577:Syndrome