Production and application of LPA polyclonal antibody.
By using colloidal gold as a hapten carrier, a kind of antibody against lysophosphatidic acid (LPA) was developed and used to successfully detect 500 ng/mL LPA in dot immunogold filtration assay. Such application of the LPA antibody could offer us a way to diagnose ovarian cancer at its early stage.
Chen
J H
JH
Ministry of Education Key Lab of Bioorganic Chemistry & Molecular Engineering, Department of Chemistry, Peking University, Beijing, PR China. jhchem@chemms.chem.pku.edu.cn
Zou
F
F
Wang
N D
ND
Xie
S W
SW
Zhang
X
X
D000906:Antibodies / Q000737:chemistry / Q000276:immunology / Q000302:isolation & purification*; D000918:Antibody Specificity; D005260:Female; D006801:Humans; D007106:Immune Sera; D008246:Lysophospholipids / Q000276:immunology*; D010051:Ovarian Neoplasms / Q000175:diagnosis
D000906:Antibodies; D007106:Immune Sera; D008246:Lysophospholipids