Unusual negative side effects of non-steroidal anti-inflammatory drugs in the proximal colon.
Two cases of uncommon side effects of non-steroidal anti-inflammatory drugs (NSAID) are presented which show that in special cases NSAID lesions can be located predominantly in the proximal colon, that NSAID-caused lesions may present themselves as diaphragm-like strictures and that alterations by NSAID in this part of the bowel may bring enormous problems for the differential diagnosis.
Kehrer
G
G
St.-Vincenz-Krankenhaus Heilbad-Heiligenstadt.
Bosseckert
H
H
Koppe
P
P
Lutz
B
B
Will
U
U
Zinsser
E
E
D000368:Aged; D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D001241:Aspirin / Q000009:adverse effects* / Q000627:therapeutic use; D003108:Colonic Diseases / Q000139:chemically induced* / Q000175:diagnosis; D003937:Diagnosis, Differential; D004008:Diclofenac / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D014456:Ulcer / Q000139:chemically induced* / Q000175:diagnosis
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac; D001241:Aspirin