Treatment of catheter-induced thrombotic superior vena cava syndrome: a single institution's experience.
Thrombosis is the most frequent benign etiology of superior vena cava syndrome among cancer patients who have a long-term central venous catheter. In this paper, six cases of thrombotic superior vena cava syndrome are discussed. There were four women and two men. One patient was treated with streptokinase and five with urokinase. The mean age was 46 years (range 22-69), and the mean time for thrombosis development after catheter insertion was 125 days (range: 53-211 days). The mean time for resolution of thrombosis was 7 days (range 2-11) in five patients. One patient had no response to fibrinolysis.
Service of Medical Oncology, Hospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Canary Islands, Spain. mmoralesg@comtf.es
M
M
Morales
V
V
Comas
M
M
Trujillo
J
J
Dorta
D000328:Adult; D000368:Aged; D002408:Catheters, Indwelling / Q000009:adverse effects*; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D013300:Streptokinase / Q000627:therapeutic use; D013479:Superior Vena Cava Syndrome / Q000188:drug therapy* / Q000209:etiology*; D016896:Treatment Outcome; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use
D005343:Fibrinolytic Agents; D013300:Streptokinase; D014568:Urokinase-Type Plasminogen Activator