Diabetic rats transplanted with adult porcine islets and immunosuppressed with cyclosporine, mycophenolate mofetil, and leflunomide remain normoglycemic for up to 100 days.
Wennberg
L
L
Department of Transplantation Surgery, Karolinska Institute, Huddinge Hospital, Huddinge, Sweden. larswennberg@transpl.hs.sll.se
Song
Z
Z
Zhang
J
J
Bennet
W
W
Nava
S
S
Bari
S
S
Sundberg
B
B
Korsgren
O
O
Groth
C G
CG
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D016572:Cyclosporine / Q000627:therapeutic use*; D003921:Diabetes Mellitus, Experimental / Q000601:surgery; D004359:Drug Therapy, Combination; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016381:Islets of Langerhans Transplantation / Q000276:immunology / Q000502:physiology*; D007555:Isoxazoles / Q000627:therapeutic use*; D000077339:Leflunomide; D009173:Mycophenolic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use; D051381:Rats; D011917:Rats, Inbred Lew; D013552:Swine; D014183:Transplantation, Heterologous / Q000276:immunology / Q000502:physiology*
D001786:Blood Glucose; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D016572:Cyclosporine; D000077339:Leflunomide; D009173:Mycophenolic Acid