Type 1 sirenomelia in one of male twins, with imperforate anus in the other male twin.
The etiology of sirenomelia sequence is still obscure. The role of maternal diabetes and a vascular steal phenomenon have been discussed [Gürakan et al. (1996) Turk J Pediatr 38:393-397]. Discordant monozygotic twin sirenomelia has been commonly reported but only rarely in dizygotic twins. The family of the presented twins had a high risk of diabetes mellitus. One of the twins has type 1 sirenomelia and the other had only an imperforate anus.
Akbiyik
F
F
Balci
S
S
Akkoyun
I
I
Aktaş
D
D
Cakmak
O
O
D001006:Anus, Imperforate / Q000473:pathology*; D004200:Diseases in Twins; D004480:Ectromelia / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D014429:Twins, Dizygotic