Pathogenicity of Erysipelothrix rhusiopathiae: virulence factors and protective immunity.
Erysipelothrix rhusiopathiae is the causative agent of erysipelas in animals and erysipeloid in humans. In the absence of specific antibodies, the organism evades phagocytosis by phagocytic cells, but even if phagocytized, it is able to replicate intracellulary in these cells. In this review, recent advances in our understanding of the pathogenicity of E. rhusiopathiae and its protective immunity are described.
Shimoji
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National Institute of Animal Health, Kannondai, Tsukuba, Ibaraki, Japan.
D000818:Animals; D004888:Erysipelothrix / Q000276:immunology / Q000472:pathogenicity*; D004889:Erysipelothrix Infections / Q000382:microbiology; D006801:Humans; D014774:Virulence