Evaluating energetics of erythropoietin ligand binding to homodimerized receptor extracellular domains.
Hensley
P
P
Pfizer Inc., Central Research Division, Groton, Connecticut 06340-9979, USA.
Doyle
M L
ML
Myszka
D G
DG
Woody
R W
RW
Brigham-Burke
M R
MR
Erickson-Miller
C L
CL
Griffin
C A
CA
Jones
C S
CS
McNulty
D E
DE
O'Brien
S P
SP
Amegadzie
B Y
BY
MacKenzie
L
L
Ryan
M D
MD
Young
P R
PR
D000818:Animals; D015374:Biosensing Techniques; D016466:CHO Cells; D002151:Calorimetry / Q000295:instrumentation / Q000379:methods; D003001:Cloning, Molecular / Q000379:methods; D006224:Cricetinae; D019281:Dimerization; D004921:Erythropoietin / Q000737:chemistry* / Q000378:metabolism*; D007700:Kinetics; D008024:Ligands; D013058:Mass Spectrometry / Q000379:methods; D008958:Models, Molecular; D016133:Polymerase Chain Reaction / Q000379:methods; D011487:Protein Conformation; D021122:Protein Subunits; D017467:Receptors, Erythropoietin / Q000737:chemistry* / Q000378:metabolism*; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D013816:Thermodynamics; D014162:Transfection / Q000379:methods; D014461:Ultracentrifugation / Q000295:instrumentation / Q000379:methods
D008024:Ligands; D021122:Protein Subunits; D017467:Receptors, Erythropoietin; D011993:Recombinant Fusion Proteins; D011994:Recombinant Proteins; D004921:Erythropoietin