Androgen effect on body composition and fat metabolism.
Recognizing the adverse metabolic effects of predominantly visceral body fat distribution associated with low testosterone levels, researchers have investigated the effects of androgen treatment on body fat distribution in men. This presentation reviews the results of research on acute and longer-term effects of treatment with testosterone and dihydrotestosterone. Methods for investigating these results, including measurement of lipoprotein lipase activity and of radiolabeled fat uptake and turnover, are described and discussed.
Jensen
M D
MD
Division of Endocrinology, Metabolism, Nutrition, and Internal Medicine, Mayo Clinic Rochester, Minn., USA.
D000273:Adipose Tissue / Q000187:drug effects* / Q000378:metabolism*; D000368:Aged; D000375:Aging / Q000187:drug effects* / Q000502:physiology*; D000728:Androgens / Q000172:deficiency / Q000502:physiology* / Q000627:therapeutic use*; D001823:Body Composition / Q000187:drug effects* / Q000502:physiology*; D001824:Body Constitution / Q000502:physiology*; D013196:Dihydrotestosterone / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008071:Lipoprotein Lipase / Q000187:drug effects / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000188:drug therapy* / Q000209:etiology*; D012727:Sex Characteristics; D013739:Testosterone / Q000172:deficiency / Q000502:physiology* / Q000627:therapeutic use*; D013997:Time Factors
D000728:Androgens; D013196:Dihydrotestosterone; D013739:Testosterone; D008071:Lipoprotein Lipase