Relation between green tea consumption and the severity of coronary atherosclerosis among Japanese men and women.
OBJECTIVE
To examine the relation between green tea consumption and arteriographically determined coronary atherosclerosis.


METHODS
Study subjects were 512 patients (302 men and 210 women) aged 30 years or older who underwent coronary arteriography for the first time at four hospitals in Fukuoka City or one hospital in an adjacent city between September 1996 and August 1997. Lifestyle characteristics including green tea consumption were ascertained before arteriography by a questionnaire supported with interview.


RESULTS
117 men (38.7%) and 50 women (23.8%) had significant stenosis of one or more coronary arteries. Green tea consumption tended to be inversely associated with coronary atherosclerosis in men, but not in women. An evident, protective association between green tea and coronary atherosclerosis was observed in a subgroup of 262 men excluding those under dietary or drug treatment for diabetes mellitus. In this subgroup, after adjustment for traditional coronary risk factors and coffee, odds ratios of significant stenosis for consumption of 2-3 cups and 4 or more cups per day were 0.5 (95% confidence interval 0.2-1.2) and 0.4 (0.2-0.9), respectively, as compared with a consumption of one cup per day or less.


CONCLUSIONS
The results indicate that green tea may be protective against coronary atherosclerosis at least in men.
Sasazuki
S
S
Department of Preventive Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Kodama
H
H
Yoshimasu
K
K
Liu
Y
Y
Washio
M
M
Tanaka
K
K
Tokunaga
S
S
Kono
S
S
Arai
H
H
Doi
Y
Y
Kawano
T
T
Nakagaki
O
O
Takada
K
K
Koyanagi
S
S
Hiyamuta
K
K
Nii
T
T
Shirai
K
K
Ideishi
M
M
Arakawa
K
K
Mohri
M
M
Takeshita
A
A
D000328:Adult; D000368:Aged; D000792:Angiography; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000517:prevention & control*; D003430:Cross-Sectional Studies; D004032:Diet; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D013662:Tea
D013662:Tea