Transcription factor NF 1 expression in involuting mammary gland.
Transcripts of each of the four NF1 genes (NF1 A, B, C (CTF/NF1) and X) are expressed in both lactating and involuting mouse mammary gland but there is an indication that increased expression of an NF1 C (CTF/NF1) transcript accompanies early involution. The involution-associated 74 kD NF1 and the 114 kD lactation-associated NF1 are recognised by an anti-NF1 C-specific antibody that does not cross-react with other NF1 proteins. It is most likely that this lactation/involution switch in NF1 factors represents a change in expression of NF1 C (CTF/NF1) proteins.
Kane
R
R
Dept. of Pharmacology, University College Dublin, Belfield, Ireland.
Finlay
D
D
Lamb
T
T
Martin
F
F
D000818:Animals; D004268:DNA-Binding Proteins / Q000502:physiology*; D005260:Female; D005786:Gene Expression Regulation / Q000502:physiology; D007774:Lactation / Q000502:physiology; D008321:Mammary Glands, Animal / Q000502:physiology*; D051379:Mice; D051839:NFI Transcription Factors; D009687:Nuclear Proteins / Q000502:physiology; D014157:Transcription Factors / Q000502:physiology*
D004268:DNA-Binding Proteins; D051839:NFI Transcription Factors; D009687:Nuclear Proteins; D014157:Transcription Factors; C080333:transcription factor nuclear factor 1