Free radical scavenging activity of Lafoensia pacari.
The methanolic extract of the stem bark of Lafoensia pacari (Lythraceae) showed free radical scavenging activity in the diphenyl picryl hydrazyl radical (DPPH) decoloration assay and inhibited the enzyme xanthine oxidase 'in vitro'. Bioassay-guided isolation led to ellagic acid (EA) as the main active compound of Brazilian and Paraguayan collections of the plant.
Solon
S
S
Pós-Graduação em Saúde e Ambiente-ISC, Dep. Química I.C.E.T., Universidade Federal de Mato Grosso, Av. Fernando Correa da Costa s/n, 78060-900 Cuiabá, MT, Brazil.
Lopes
L
L
Teixeira de Sousa
P
P
Schmeda-Hirschmann
G
G
D000438:Alcohols; D001938:Brazil; D002851:Chromatography, High Pressure Liquid; D016166:Free Radical Scavengers / Q000302:isolation & purification / Q000494:pharmacology*; D005609:Free Radicals / Q000737:chemistry; D019441:Plant Epidermis / Q000737:chemistry; D010936:Plant Extracts / Q000494:pharmacology; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D014867:Water; D014969:Xanthine Oxidase / Q000378:metabolism
D000438:Alcohols; D016166:Free Radical Scavengers; D005609:Free Radicals; D010936:Plant Extracts; D014867:Water; D014969:Xanthine Oxidase