title: Glibenclamide induced chronic cholestasis simulating primary biliary cirrhosis: a case report.
abstract: A 43-year-old lady with long standing non-insulin dependent diabetes mellitus on glibenclamide presented with cholestatic liver disease. Initially she was thought to have developed primary biliary cirrhosis (PBC). When she made a spontaneous recovery following the withdrawal of glibenclamide, it became obvious that the patient had been suffering from drug-induced chronic cholestasis (DICC). The subtle differences between PBC and DICC are highlighted.
authors.affiliation: Department of Medicine, Taiping Hospital, Perak.
authors.forename: M
authors.initials: M
authors.lastname: Ramanathan
authors.forename: S
authors.initials: S
authors.lastname: Wahinuddin
authors.forename: S T
authors.initials: ST
authors.lastname: Kew
mesh_terms: D000328:Adult; D002779:Cholestasis / Q000139:chemically induced* / Q000175:diagnosis*; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D005905:Glyburide / Q000009:adverse effects*; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis*
chemical_list: D005905:Glyburide