title: Batch and continuous cultivation of Anaerobiospirillum succiniciproducens for the production of succinic acid from whey.
abstract: Batch and continuous cultivation of Anaerobiospirillum succiniciproducens were systematically studied for the production of succinic acid from whey. Addition of 2.5 g l(-1) yeast extract and 2.5 g l(-1) polypeptone per 10 g l(-1) whey was most effective for succinic acid production from both treated and nontreated whey. When 20 g l(-1) nontreated whey and 7 g l(-1) glucose were used as cosubstrates, the yield and productivity of succinic acid reached at the end of fermentation were 95% and 0.46 g (1 h)(-1), respectively. These values were higher than those obtained using nontreated whey alone [93% and 0.24 g (1 h)(-1) for 20 g l(-1) whey]. Continuous fermentation of A. succiniciproducens at an optimal dilution rate resulted in the production of succinic acid with high productivity [1.35 g (1 h)(-1)], high conversion yield (93%), and higher ratio of succinic acid to acetic acid (5.1:1) from nontreated whey.
authors.affiliation: Department of Chemical Engineering and BioProcess Engineering Research Center, Korea Advanced Institute of Science and Technology, Taejon.
authors.forename: P C
authors.initials: PC
authors.lastname: Lee
authors.forename: W G
authors.initials: WG
authors.lastname: Lee
authors.forename: S
authors.initials: S
authors.lastname: Kwon
authors.forename: S Y
authors.initials: SY
authors.lastname: Lee
authors.forename: H N
authors.initials: HN
authors.lastname: Chang
mesh_terms: D001421:Bacteria, Anaerobic / Q000254:growth & development* / Q000378:metabolism; D003470:Culture Media; D003611:Dairy Products; D005285:Fermentation; D005947:Glucose; D007785:Lactose; D019802:Succinic Acid / Q000378:metabolism*
chemical_list: D003470:Culture Media; D019802:Succinic Acid; D005947:Glucose; D007785:Lactose