title: [Medicated intravascular catheters. Review of the literature].
abstract: Central Venous Catheters (CVC) are widely used in the setting of intensive care units, but they are associated with an increased risk of CVC-related infections. To prevent infections originated from CVC, a number of devices have been more recently produced, that are characterized by the presence of antiseptic/antibiotic substances in the matrix of the CVC itself ("impregnated" CVC). In this brief review, more recent studies on the topic are discussed, especially in the light of guidelines from the CDC. Although from these studies many suggestions about the efficacy of impregnated CVC in the prevention of CVC-related infections can be derived, notwithstanding the critical role of preventive measures during CVC procedures must be recognized as the principal factor in reducing CVC infections.
authors.affiliation: Servizio Trapianti di Midollo Osseo Unità Operativa Ematologia Azienda Ospedaliera Careggi Firenze.
authors.forename: L
authors.initials: L
authors.lastname: Rasero
authors.forename: M
authors.initials: M
authors.lastname: Degl'Innocenti
authors.forename: G
authors.initials: G
authors.lastname: Tellarini
mesh_terms: D000900:Anti-Bacterial Agents; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000295:instrumentation*; D002408:Catheters, Indwelling / Q000009:adverse effects* / Q000600:supply & distribution*; D002487:Centers for Disease Control and Prevention, U.S.; D020099:Coated Materials, Biocompatible / Q000600:supply & distribution*; D003422:Critical Care; D003428:Cross Infection / Q000209:etiology / Q000517:prevention & control; D004866:Equipment Contamination / Q000517:prevention & control; D006801:Humans; D017053:Infection Control / Q000379:methods; D017410:Practice Guidelines as Topic; D014481:United States
chemical_list: D000900:Anti-Bacterial Agents; D020099:Coated Materials, Biocompatible