Management and prevention of meningococcal disease.
While many other illnesses affecting children have been contained or even eliminated, meningococcal disease has become a leading infectious cause of death. The major management challenge may be increased intracranial pressure or toxic shock, depending on whether meningitis or septicemia predominates. A new protein-conjugated group C vaccine is expected to reduce deaths by as much as 40%.
Mehta
N
N
Department of Pediatrics, St. Mary's Hospital, London, United Kingdom.
Levin
M
M
D000293:Adolescent; D000671:Amputation, Surgical; D016470:Bacteremia / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D002675:Child, Preschool; D004638:Emergency Treatment / Q000379:methods; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D008585:Meningitis, Meningococcal / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D008589:Meningococcal Infections / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D011322:Primary Prevention / Q000379:methods; D006113:United Kingdom / Q000453:epidemiology; D014481:United States / Q000453:epidemiology; D014611:Vaccination