title: Megalophallus as a sequela of priapism in sickle cell anemia: use of blood oxygen level-dependent magnetic resonance imaging.
abstract: Priapism is a common complication of sickle cell anemia. We report a little known sequela of priapism: painless megalophallus, with significant penile enlargement. The patient had had an intense episode of priapism 9 years previously and his penis remained enlarged. Blood oxygen level-dependent magnetic resonance imaging revealed enlarged, hypoxic corpora cavernosa. Megalophallus probably resulted from permanent loss of elasticity of the tunica albuginea due to severe engorgement during the episode of priapism. This sequela needs to be recognized by physicians because no intervention is necessary and sexual function seems to remain intact.
authors.affiliation: Department of Medicine (Division of Hematology), Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York 10461, USA.
authors.forename: A A
authors.initials: AA
authors.lastname: Kassim
authors.forename: H
authors.initials: H
authors.lastname: Umans
authors.forename: R L
authors.initials: RL
authors.lastname: Nagel
authors.forename: M E
authors.initials: ME
authors.lastname: Fabry
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D006801:Humans; D006984:Hypertrophy / Q000209:etiology / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D010413:Penis / Q000473:pathology*; D011317:Priapism / Q000150:complications*