title: Solitary metastases to the cranial vault. Report of ten cases.
abstract: BACKGROUND
  Metastatic spread of tumors to the skull is quite unusual and often represents a relevant diagnostic and therapeutic problem. Skull involvement can be observed in various neoplasms of epithelial origin (rarely in other tumors) and most often responsible are lung, breast, thyroid, kidney and prostate cancers. Less frequent than multiple involvement, single cranial vault lesions are often amenable to surgical resection instead of radiotherapy alone; scope of this paper is to highlight the key points of the management of such entities, including a brief review of the pathological and radiological features of these entities.
  
  
  METHODS
  A retrospective study has enabled us to select from our files ten cases of surgically treated solitary cranial vault metastases, with a variable follow-up ranging from 6 months to 4 years. In all the cases the operation consisted in a monobloc resection and a cranioplasty for the repair of the defect.
  
  
  RESULTS
  We have observed no perioperative morbidity or mortality; in all the cases surgery allowed histologic confirmation and immediate relief of neurological symptoms and cosmetic impairment (when present).
  
  
  CONCLUSIONS
  Monobloc resection of solitary cranial vault metastatic lesions is an easy made and safe procedure, to be performed in every patient except the ones in poor general conditions, which are better addressed to radiotherapy alone.
authors.affiliation: Department of Neurosciences, Institute of Neurosurgery, University of Rome Tor Vergata, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Artico
authors.forename: G M
authors.initials: GM
authors.lastname: De Caro
authors.forename: M
authors.initials: M
authors.lastname: Salvati
authors.forename: S
authors.initials: S
authors.lastname: Carloia
authors.forename: E
authors.initials: E
authors.lastname: Rastelli
authors.forename: V
authors.initials: V
authors.lastname: Wierzbicki
authors.forename: M
authors.initials: M
authors.lastname: Manni
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012888:Skull Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome