Unusual ultrastructural features in intrafascicular ganglion cells of the rat pelvic nerve.
The incidental finding of four ectopic ganglion cells within the pelvic nerve of a normal rat prompted a thorough electron microscopic investigation of the ultrastructural features of these neurons. They were found to enwrap presynaptic terminals inside crater-like invaginations; the appositional surfaces were made more complex by the presence of slender dendritic appendages and sheet-like processes of glial cells. The presynaptic elements contained both clear and dense-cored vesicles, and appeared similar to those characterizing SIF (paraneuronal) cells. In addition, cilia were encountered in both the invaginated processes and most of the Schwann cells associated with the pre- and postsynaptic nerve cells and their processes. Overall, these features were deemed worth reporting because 1) of the unusual features of synaptic input from a SIF cell to a ganglion cell associated with the pelvic plexus, and 2) the ectopic ganglion cells possibly represent the sole example, other than ciliary neurones in the avian ciliary ganglion, of postsynaptic cells encasing presynaptic endings inside their perikarya.
Fiori
M G
MG
Department of Orthopedics, University of Brescia School of Medicine, Italy.
Petrelli
L
L
Nunzi
M G
MG
D000818:Animals; D002923:Cilia / Q000648:ultrastructure; D005724:Ganglia / Q000166:cytology / Q000648:ultrastructure*; D008297:Male; D008870:Microtubules / Q000648:ultrastructure; D009474:Neurons / Q000648:ultrastructure; D010388:Pelvis / Q000294:innervation*; D017729:Presynaptic Terminals / Q000648:ultrastructure; D051381:Rats; D017207:Rats, Sprague-Dawley; D012583:Schwann Cells / Q000648:ultrastructure