title: New purine derivatives for efficient preparation of nucleoside analogs via alkylation.
abstract: New diazabicycloundecenium and phosphazenium derivatives of purines are introduced for mild and efficient preparation of nucleoside analogs via in situ alkylation. Diazabicycloundecenium salts of purines were obtained directly as a result of an unusual reaction between two corresponding amino compounds.
authors.affiliation: Process Development, Chemical and Agricultural Products Division, Abbott Laboratories, North Chicago, IL 60064-6291, USA.
authors.forename: K A
authors.initials: KA
authors.lastname: Lukin
authors.forename: C X
authors.initials: CX
authors.lastname: Yang
authors.forename: J R
authors.initials: JR
authors.lastname: Bellettini
authors.forename: B A
authors.initials: BA
authors.lastname: Narayanan
mesh_terms: D000478:Alkylation; D001372:Aza Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D055598:Chemical Phenomena; D002621:Chemistry; D009705:Nucleosides / Q000138:chemical synthesis*; D011687:Purines / Q000138:chemical synthesis
chemical_list: D001372:Aza Compounds; D009705:Nucleosides; D011687:Purines