Detection of apoptotic cells in Vero cell cultures inoculated with samples derived from fatal cases of Sarawak acute childhood viral infection.
Infectious agent(s) causing the fatal Sarawak acute childhood viral infection (SACVI) has not been identified. In the present study, results indicating that inocula prepared from the fatal cases of SACVI induced apoptosis in Vero cell cultures are presented. These findings suggest the possible involvement of apoptotic cellular responses in SACVI.
AbuBakar
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S
Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur.
Shafee
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N
Chee
H Y
HY
D000208:Acute Disease; D000818:Animals; D017209:Apoptosis; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D002522:Chlorocebus aethiops; D053938:DNA Fragmentation; D004279:DNA, Viral / Q000235:genetics; D006801:Humans; D020287:In Situ Nick-End Labeling; D008296:Malaysia; D014709:Vero Cells / Q000502:physiology* / Q000821:virology*; D014777:Virus Diseases / Q000235:genetics / Q000401:mortality / Q000503:physiopathology*
D004279:DNA, Viral