title: Value of acoustic rhinometry in environmental medicine.
abstract: It is a weak point of environmental medicine that health disturbances, e.g. functional affections of the upper respiratory tract, cannot be objectively judged by physicians resp. researchers. In this study, the validity of acoustic rhinometry, a method giving information on cross-sectional areas of the upper airways by means of ultrasound probing, was tested in 40 volunteers seven times during one year. Furthermore, using a simplified model of the nose the accuracy of this method to measure the minimal cross-sectional area (MCA) in the nose was tested. The measurements were extremely confounded by the mode of connection to the nose (e.g. selected adapter, direction of application) and by the MCA in the nasal cavity. Statistical analyses showed a good reproducibility of measurements repeated within minutes, but suggested an intrapersonal variability over the analyzed examination phases due to apparatus independent factors. However, this variability could not be explained by influencing and confounding factors obtained by questionnaire, medical history, and physical examination. The test model showed little to great errors (1.5 to 568.5%) between the actual and the measured MCA, depending on the diameter. It is concluded that the method of acoustic rhinometry has to be standardized before it's value for environmental medicine can finally be judged. Further studies are necessary that should focus among others on factors influencing the variability of MCA and the effect of MCA on the measurement of the area behind the MCA. So far, the use of acoustic rhinometry for the evaluation of nasal function cannot be recommended.
authors.affiliation: Institut für Hygiene und Umweltmedizin des Universitätsklinikums, Rheinisch-Westfälischen Technischen Hochschule Aachen. GA.Wiesmueller@post.rwth-aachen.de
authors.forename: G A
authors.initials: GA
authors.lastname: Wiesmüller
authors.forename: A
authors.initials: A
authors.lastname: Steup
authors.forename: U
authors.initials: U
authors.lastname: Ranft
authors.forename: C
authors.initials: C
authors.lastname: Bachert
mesh_terms: D000162:Acoustics; D000293:Adolescent; D000328:Adult; D004784:Environmental Monitoring / Q000379:methods / Q000592:standards*; D062665:Epidemiological Monitoring; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods; D015508:Nasal Obstruction / Q000175:diagnosis* / Q000503:physiopathology; D012016:Reference Values; D015203:Reproducibility of Results; D012140:Respiratory Tract Diseases / Q000175:diagnosis* / Q000453:epidemiology; D012621:Seasons