Congenital hypopituitarism in a 48-year old adult. Natural course, hormonal study and MRI evidence.
A case of Congenital Hypopituitarism (CH) in an untreated 48 yr-old-man is reported. The hormonal studies demonstrated a panhypopituitarism and MR imaging revealed absence of pituitary stalk, small anterior pituitary remnant on the sella floor and ectopic neurohypophysis at the tuber cinereum. The pattern of hormonal responsiveness suggests that CH encompasses findings typical of primary anterior pituitary disease and those of hypothalamic dysfunction.
Pentimone
F
F
Department of Internal Medicine, University of Pisa.
Riccioni
S
S
Del Corso
L
L
D000365:Age Determination by Skeleton; D003456:Cryptorchidism / Q000209:etiology; D003483:Cutis Laxa / Q000209:etiology; D004393:Dwarfism, Pituitary / Q000209:etiology; D006728:Hormones / Q000097:blood; D006801:Humans; D007018:Hypopituitarism / Q000097:blood / Q000151:congenital / Q000175:diagnosis* / Q000473:pathology; D007021:Hypospadias / Q000209:etiology; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology; D007037:Hypothyroidism / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010903:Pituitary Gland, Anterior / Q000473:pathology; D010904:Pituitary Gland, Posterior / Q000473:pathology; D011628:Puberty, Delayed / Q000209:etiology
D006728:Hormones