title: Clinical features and associated radiological abnormalities in 54 patients with cavum septi pellucidi.
abstract: OBJECTIVE
  To determine the clinical and radiological features of the patients who were found to have cavum septum pellucidum (CSP) on the cranial computerized tomographic (CT) scans.
  
  
  METHODS
  Fifty four consecutive cases of cavum septum pellucidum were detected amongst 1,281 patients who underwent cranial CT scans; their clinical and radiological features were studied.
  
  
  RESULTS
  Recurrent seizures and developmental delay were the commonest presenting symptoms seen. Significant neurological deficits were present in 75.9% of these cases. Additional cerebral abnormalities were observed in the CT scan in 76% of cases, the commonest being cortical atrophy, cerebral infarction and hydrocephalus.
  
  
  CONCLUSIONS
  There seems to be a strong association between CSP and certain neurological abnormalities in the population studied. Further interpretation of this study would be possible if normal population in this geographical area is screened for CSP using cranial CT scans or magnetic resonance imaging.
authors.affiliation: Department of Paediatrics, Universiti Sains Malaysia Hospital, Kota Bharu, Kelantan.
authors.forename: A K
authors.initials: AK
authors.lastname: Guru Raj
authors.forename: R C
authors.initials: RC
authors.lastname: Pratap
authors.forename: R
authors.initials: R
authors.lastname: Jayakumar
authors.forename: W A
authors.initials: WA
authors.lastname: Ariffin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology*; D012008:Recurrence; D012640:Seizures / Q000209:etiology*; D012688:Septum Pellucidum / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed