title: Evaluation of a new module in the continuous monitoring of respiratory mechanics.
abstract: OBJECTIVE
  Bedside monitoring of respiratory mechanics facilitates the use of lung protective ventilation in acute lung injury (ALI). We evaluated a new clinical monitor of respiratory mechanics.
  
  
  METHODS
  Prospective, in vitro and in vivo study.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Measurements were done using a lung model and in patients after cardiac surgery (n = 10) and in patients with ALI (n = 10).
  
  
  METHODS
  The monitor provides continuous monitoring of pressure, flow and volume waveform and loop data, and automatically collected variables of respiratory mechanics. Breath-by-breath respiratory mechanics data and the automated variables obtained with the new monitor were compared with flow and pressure reference data.
  
  
  RESULTS
  Waveform data comparison showed errors of less than 5% for most variables. Automatically recorded respiratory pressures and volumes showed good agreement within clinical standards when compared to reference (errors from 2.5% to 6.2%). Automatically recorded derived variables present poor agreement (errors from 8.1% to 158.3%).
  
  
  CONCLUSIONS
  The waveform data of the new monitor is accurate. The value of the automatically derived variables is limited by the fact that inspiratory plateau pressure and plateau compliance have no direct physiological meaning. Nevertheless, in clinical monitoring much information can be derived from the waveform signals alone and from pressure-volume and flow-volume loops. These facilitate monitoring changes in respiratory mechanics in the ALI patient.
authors.affiliation: Department of Anesthesiology and Intensive Care, Kuopio University Hospital, Finland.
authors.forename: S
authors.initials: S
authors.lastname: Nunes
authors.forename: J
authors.initials: J
authors.lastname: Takala
mesh_terms: D000328:Adult; D000368:Aged; D001026:Coronary Artery Bypass; D006801:Humans; D066298:In Vitro Techniques; D008875:Middle Aged; D008954:Models, Biological; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D019095:Point-of-Care Systems; D011182:Postoperative Care; D011446:Prospective Studies; D012016:Reference Values; D012121:Respiration, Artificial / Q000295:instrumentation*; D012128:Respiratory Distress Syndrome / Q000175:diagnosis; D012129:Respiratory Function Tests / Q000295:instrumentation*; D015656:Respiratory Mechanics; D013147:Spirometry / Q000295:instrumentation