title: Testing the central vestibular functions: a clinical survey.
abstract: In vestibular examinations anomalies in the saccade and smooth pursuit tests as well as the fixation suppression after caloric stimulation might indicate central lesions in the vestibular system. Additionally, a high gain in the torsion test is suspicious of cerebellar dysfunction. In this study, 141 patients out of 973 had at least one of these anomalies. For 125 patients we were able to compare the initial findings in the vestibular examination with the final diagnosis by otologists, neurologists and general practitioners. The complaints of 37.6% of the patients with these electronystagmographic (ENG) anomalies appeared to be of central origin. Abnormal saccades, an abnormal smooth pursuit, and an elevated gain in the torsion test were not independently diagnostic for central vestibular disease. The fixation suppression index appeared to be lower for subjects with peripheral vestibular disease. Otologists more often referred their patients to a neurologist if the fixation index was elevated.
authors.affiliation: Department of Otolaryngology, University Hospital Utrecht, Utrecht, The Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: van der Torn
authors.forename: J E
authors.initials: JE
authors.lastname: van Dijk
mesh_terms: D000293:Adolescent; D000368:Aged; D000369:Aged, 80 and over; D002493:Central Nervous System Diseases / Q000175:diagnosis; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004584:Electronystagmography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015837:Vestibular Diseases / Q000175:diagnosis; D014724:Vestibular Function Tests