[Activity of gastric mucosal NO synthase in duodenal ulcer].
The paper covers the results of 32 endoscopic studies. The D. E. Korzhevsky procedure was used to determine the activity of NADP.H diaphorase, a NO-synthase marker, in gastric mucosal biopsy specimens from patients with acute and scarring peptic ulcer. A high activity of NO synthase was found in patients with acute ulcer and its inhibition was ascertained in those with scarring ulcer. The findings lead to the conclusion that NO-dependent mechanisms are involved in the pathogenesis of an ulcerative process.
Gozhenko
A I
AI
Nasibullin
B A
BA
Kokhno
Iu S
IuS
D000293:Adolescent; D000328:Adult; D015415:Biomarkers; D001706:Biopsy; D018450:Disease Progression; D004381:Duodenal Ulcer / Q000201:enzymology* / Q000473:pathology; D005260:Female; D005753:Gastric Mucosa / Q000201:enzymology* / Q000473:pathology; D006801:Humans; D008297:Male; D009252:NADPH Dehydrogenase / Q000378:metabolism; D019001:Nitric Oxide Synthase / Q000378:metabolism*
D015415:Biomarkers; D019001:Nitric Oxide Synthase; D009252:NADPH Dehydrogenase