[The clinical value of determination of fibronectin: the endothelium lesion marker in EPH-gestosis].
Plasma fibronectin concentration, AT III, PAI-1 and platelet count in 115 patients with gestosis, chronic hypertension and in physiological pregnancy were estimated. The obtained results indicate the significant fibronectin increase in gestosis patients. The positive correlation between fibronectin concentration and gestosis index was found. PAI-1 activity appeared to be the only haemostatic parameter which significantly increased in toxaemia. Prophylaxis with acetylosalicylic acid did not affect the fibronectin concentration. Fibronectin determination allows to differentiate toxaemic patients from the chronic hypertension cases. The high specificity and sensitivity of the test implies its important clinical role.
Falkowski
B
B
Oddziału Połozniczo-Ginekologicznego Samodzielnego Publicznego Szpitala Wojewódzkiego w Suwałkach.
Soszka
J
J
Soszka
T
T
Piszka
J
J
D000328:Adult; D004730:Endothelium, Vascular / Q000737:chemistry*; D005260:Female; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood / Q000175:diagnosis*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000175:diagnosis*; D012189:Retrospective Studies
D005353:Fibronectins