title: Vertebral hemangioma mimicking a metastatic bone lesion in well-differentiated thyroid carcinoma.
abstract: The authors report a case of abnormal accumulation of I-131 in a thoracic vertebra in a patient with a well-differentiated thyroid carcinoma. The presumptive diagnosis was metastatic bone disease. Further diagnostic work-up confirmed a benign bone lesion. Bone metastasis, when shown on I-131 whole-body scintigraphy, usually supports a change in the staging and therapeutic approach to a patient with thyroid carcinoma. The authors believe that, although an infrequent lesion, the differential diagnosis of abnormal accumulation of I-131 in the body of a vertebra in patients with well-differentiated thyroid carcinoma should raise the possibility of a benign hemangioma. Complete work-up of the suggested bone metastatic lesion should be performed before tumor restaging and I-131 therapy is recommended.
authors.affiliation: Radiological Science Department, School of Medicine, University of Puerto Rico, Rio Piedras, USA.
authors.forename: R
authors.initials: R
authors.lastname: Laguna
authors.forename: F
authors.initials: F
authors.lastname: Silva
authors.forename: J
authors.initials: J
authors.lastname: Vazquez-Sellés
authors.forename: E
authors.initials: E
authors.lastname: Orduña
authors.forename: C
authors.initials: C
authors.lastname: Flores
mesh_terms: D002291:Carcinoma, Papillary / Q000000981:diagnostic imaging / Q000556:secondary*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006391:Hemangioma / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging*; D013964:Thyroid Neoplasms / Q000473:pathology*; D013965:Thyroidectomy; D014057:Tomography, X-Ray Computed; D014915:Whole-Body Counting
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals