title: Time to reconsider the pre-oxygenation during induction of anaesthesia.
abstract: Atelectasis is a frequent finding in paralysed and mechanically ventilated patients. Atelectasis, causing shunt, impairs oxygenation and could contribute to postoperative pulmonary complications. Pre-oxygenation used during anaesthesia induction causes atelectasis. A lowering of oxygen fraction from 100% to 80% does not shorten the safety time of apnoea period, particularly useful for a difficult intubation, but it reduces drastically the atelectasis incidence.
authors.affiliation: Department of Medical Sciences, Clinical Physiology, University Hospital, Uppsala, Sweden.
authors.forename: G
authors.initials: G
authors.lastname: Hedenstierna
authors.forename: L
authors.initials: L
authors.lastname: Edmark
authors.forename: K K
authors.initials: KK
authors.lastname: Aherdan
mesh_terms: D000758:Anesthesia; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology* / Q000503:physiopathology; D010102:Oxygen Inhalation Therapy; D011300:Preoperative Care / Q000379:methods*; D001261:Pulmonary Atelectasis / Q000209:etiology* / Q000503:physiopathology