[Regulation of potassium channel function in T lymphocytes by intracellular second messengers for calcium, cyclic AMP and membrane lipid metabolites].
This review focuses on the influence of well-known intracellular second messengers on the activity of potassium channels expressed in human T lymphocytes. Basic biophysical properties of the channels are briefly presented. Available data on the regulatory role of intracellular calcium and cyclic AMP is reviewed. Finally, a possible influence of lipid compounds, especially high-density lipoproteins, lysophospholipids and sphingolipids, on the expression and activity of potassium channels in human T lymphocytes is discussed.
Teisseyre
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Katedra i Zakład Biofizyki Akademii Medycznej we Wrocławiu.
D002118:Calcium / Q000378:metabolism*; D000242:Cyclic AMP / Q000378:metabolism*; D006801:Humans; D008563:Membrane Lipids / Q000378:metabolism*; D015221:Potassium Channels / Q000378:metabolism*; D015290:Second Messenger Systems / Q000502:physiology*; D013601:T-Lymphocytes / Q000378:metabolism*
D008563:Membrane Lipids; D015221:Potassium Channels; D000242:Cyclic AMP; D002118:Calcium