title: Brain involvement in Hodgkin's disease: case reports and review of the literature.
abstract: Hodgkin's disease involving in the central nervous system is extremely rare. It usually spreads contiguously, as visceral involvement is generally thought to occur secondary to involved adjacent lymph nodes. We report three such cases found in our institution in the last two decades. Based upon our limited experience together with reported data, whole brain irradiation combined with systemic chemotherapy remains the treatment of choice for these lesions.
authors.affiliation: Radiation Oncology Division, National Cancer Center Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nakayama
authors.forename: K
authors.initials: K
authors.lastname: Tokuuye
authors.forename: Y
authors.initials: Y
authors.lastname: Kagami
authors.forename: M
authors.initials: M
authors.lastname: Sumi
authors.forename: S
authors.initials: S
authors.lastname: Murayama
authors.forename: M
authors.initials: M
authors.lastname: Kawashima
authors.forename: A
authors.initials: A
authors.lastname: Imai
authors.forename: H
authors.initials: H
authors.lastname: Ikeda
authors.forename: K
authors.initials: K
authors.lastname: Tobinai
mesh_terms: D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006689:Hodgkin Disease / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008297:Male