title: Downbeat nystagmus associated with intravenous patient-controlled administration of morphine.
abstract: This case documents a patient who developed dizziness with downbeating nystagmus while receiving a relatively large dose of IV patient-controlled analgesia morphine. Although there have been case reports of epidural morphine with these symptoms and signs, this has not been previously documented with IV or patient-controlled analgesia morphine.
authors.affiliation: Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
authors.forename: R D
authors.initials: RD
authors.lastname: Henderson
authors.forename: E F
authors.initials: EF
authors.lastname: Wijdicks
mesh_terms: D015360:Analgesia, Epidural / Q000009:adverse effects*; D016058:Analgesia, Patient-Controlled / Q000009:adverse effects*; D000701:Analgesics, Opioid / Q000009:adverse effects* / Q000627:therapeutic use; D004562:Electrocardiography; D016629:Esophagectomy; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000009:adverse effects* / Q000627:therapeutic use; D009759:Nystagmus, Pathologic / Q000139:chemically induced* / Q000503:physiopathology; D010149:Postoperative Pain / Q000188:drug therapy
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine