title: [Rupture of the patellar ligament one month after treatment with fluoroquinolone].
abstract: Musculoskeletal disorders including arthralgia and myalgia are adverse effect common to all fluoroquinolones. We report a case of spontaneous rupture of the patellar ligament in a 37-year-old man participating in leisure sports which occurred one month after a three-week course of Ciprofloxacine(R). Several cases of tendon ruptures have been reported in the literature, including the patellar tendon. Unusual features in our case were the one-month delay before tendon rupture and the absence of inaugural signs. We reviewed the pathophysiological mechanisms leading to fluoroquinolone-related tendon rupture as well as the risk factors and discussed proper management. Care must be taken when prescribing fluoroquinolones for patients at risk. Close follow-up is most important.
authors.affiliation: Service d'Urologie, CHRU et Université de Lille, 59037 Lille Cedex,, France.
authors.forename: F
authors.initials: F
authors.lastname: Saint
authors.forename: G
authors.initials: G
authors.lastname: Gueguen
authors.forename: J
authors.initials: J
authors.lastname: Biserte
authors.forename: C
authors.initials: C
authors.lastname: Fontaine
authors.forename: E
authors.initials: E
authors.lastname: Mazeman
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects*; D002939:Ciprofloxacin / Q000009:adverse effects*; D006801:Humans; D007718:Knee Injuries / Q000139:chemically induced*; D008297:Male; D017847:Patellar Ligament / Q000293:injuries*; D011704:Pyelonephritis / Q000188:drug therapy; D012422:Rupture, Spontaneous / Q000139:chemically induced; D013708:Tendon Injuries / Q000139:chemically induced*
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin