[Angiotensin converting enzyme gene polymorphism in type 2 diabetes mellitus].
The aim of this study is the assessment of the association of human angiotensin-converting enzyme gene I/D polymorphism with type 2 diabetes in 155 diabetic patients and 139 healthy individuals. These polymorphism were studied using polymerase chain reaction. Angiotensin converting enzyme gene DD genotype associated with type 2 diabetes in overweight and obese patients and patients with normal total plasma cholesterol. There is also association of DD genotype with arterial hypertension and with myocardial infarction in type 2 diabetic patients.
Puźniak
A
A
I Katedra i Klinika Chorób Wewnetrznych AM w Lublinie.
Dzida
G
G
Sobstyl
J
J
Biłan
A
A
Hanzlik
J
J
D000368:Aged; D002784:Cholesterol / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000201:enzymology / Q000235:genetics*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D009765:Obesity / Q000150:complications; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D016133:Polymerase Chain Reaction / Q000379:methods; D011110:Polymorphism, Genetic / Q000235:genetics*; D012189:Retrospective Studies
D002784:Cholesterol; D007703:Peptidyl-Dipeptidase A