title: Glucose: a reevaluation of its intraoperative use in paediatric surgery.
abstract: Blood glucose concentration was measured in 100 children immediately before and during surgery. These children were randomly assigned to receive either lactated Ringer's (LR) solution or 5% dextrose in lactated Ringer's (5%D/LR) intraoperatively as maintenance and replacement fluids. Blood samples were taken immediately after induction of anaesthesia and at 1/2, 1, 1.5, 2 and subsequent hours. Blood glucose concentration was assayed by a reflectance meter. None of the patients was noted to be hypoglycaemic pre- and intraoperatively. Intraoperative blood glucose concentration increased significantly (p < 0.05) from preoperative levels for both groups of children but the increase in those that received 5%D/LR was significantly greater (p < 0.05) than those who received LR. The number of children who were hyperglycaemic during surgery was also greater in those who received 5% dextrose in lactated Ringer's as their intraoperative fluid. These data suggest that lactated Ringer's alone is a safe and appropriate fluid for intraoperative fluid therapy in children.
authors.affiliation: Department of Anaesthesiology and Intensive Care, Universiti Kebangsaan Malaysia, Kuala Lumpur.
authors.forename: S K
authors.initials: SK
authors.lastname: Lim
authors.forename: S P
authors.initials: SP
authors.lastname: Loh
mesh_terms: D000367:Age Factors; D001786:Blood Glucose / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D005440:Fluid Therapy; D006801:Humans; D007223:Infant; D007552:Isotonic Solutions / Q000494:pharmacology; D016343:Monitoring, Intraoperative; D000077325:Ringer's Lactate
chemical_list: D001786:Blood Glucose; D007552:Isotonic Solutions; D000077325:Ringer's Lactate