title: Comparison of two alpha-cyano pyrethroids when impregnated into bednets against a pyrethroid resistant and susceptible strain of Anopheles stephensi (Diptera: Culicidae) and their F1 progeny.
abstract: The two alpha-cyano pyrethroid insecticides lambda-cyhalothrin and alpha-cypermethrin were tested as bednet treatments at a target dose of 20 mg m-2. To establish their efficacy, female pyrethroid resistant and susceptible Anopheles stephensi Liston, and the F1-hybrids were allowed to fly freely in a room with a human subject under an impregnated net. Both treatments provided good personal protection by significantly reducing the number of blood fed mosquitoes compared to an untreated control net. Mortality after 24 h was significantly higher for the alpha-cypermethrin treated net when compared to lambda-cyhalothrin. For each insecticide there were no significant differences in the proportion of susceptible homozygotes and F1-hybrids found dead after a 24 h holding period, which suggests that there would be no selection for pyrethroid resistant heterozygotes by either of the insecticides.
authors.affiliation: London School of Hygiene and Tropical Medicine, Department of Infectious and Tropical Diseases, Disease Control and Vector Biology Unit, Keppel Street, London, WC1E 7HT, UK. Jan.Kolaczinski@lshtm.ac.uk
authors.forename: J H
authors.initials: JH
authors.lastname: Kolaczinski
authors.forename: C F
authors.initials: CF
authors.lastname: Curtis
mesh_terms: D000818:Animals; D000852:Anopheles; D001512:Bedding and Linens; D005260:Female; D006801:Humans; D007305:Insecticide Resistance; D008297:Male; D009032:Mosquito Control / Q000379:methods; D011722:Pyrethrins
chemical_list: D011722:Pyrethrins