title: A preliminary investigation of remifentanil as a labor analgesic.
abstract: In this preliminary investigation, we evaluated the safety and analgesic efficacy of IV remifentanil for labor pain. Four women were studied, and then the trial was terminated because administration of this novel synthetic opioid produced significant maternal side effects in the absence of effective pain control.
authors.affiliation: Division of Women's Anesthesia, Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA. olufo001@mc.duke.edu
authors.forename: A J
authors.initials: AJ
authors.lastname: Olufolabi
authors.forename: J V
authors.initials: JV
authors.lastname: Booth
authors.forename: H G
authors.initials: HG
authors.lastname: Wakeling
authors.forename: P S
authors.initials: PS
authors.lastname: Glass
authors.forename: D H
authors.initials: DH
authors.lastname: Penning
authors.forename: J D
authors.initials: JD
authors.lastname: Reynolds
mesh_terms: D000328:Adult; D016362:Analgesia, Obstetrical / Q000009:adverse effects; D018686:Anesthetics, Intravenous / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D006801:Humans; D010147:Pain Measurement / Q000187:drug effects; D010880:Piperidines / Q000008:administration & dosage / Q000009:adverse effects; D011247:Pregnancy; D000077208:Remifentanil; D013997:Time Factors
chemical_list: D018686:Anesthetics, Intravenous; D010880:Piperidines; D000077208:Remifentanil