title: Effect of colectomy on gastric emptying in idiopathic slow-transit constipation.
abstract: BACKGROUND
  Gastric emptying is delayed in patients with idiopathic slow-transit constipation (ISTC). Gastric emptying was measured before and after colectomy and ileorectal anastomosis in patients with ISTC to determine whether the abnormality persists after operation.
  
  
  METHODS
  Twelve patients undergoing colectomy for severe ISTC had solid-phase gastric emptying measured after an overnight fast. All 12 had an uncomplicated subtotal colectomy and ileorectal anastomosis; 11 had an excellent functional outcome. In ten of these patients gastric emptying was repeated within 3 months of operation. Seven patients (including the remaining two) had the study performed at 1 year.
  
  
  RESULTS
  All 12 patients had severely delayed gastric emptying before operation. Gastric emptying remained delayed in the ten patients who underwent an early postoperative gastric emptying study. Six of seven patients assessed at 1 year had improved gastric emptying, of whom four had returned to normal. Functional outcome did not relate to gastric emptying.
  
  
  CONCLUSIONS
  Patients with ISTC have delayed gastric emptying. In some patients this returns to normal after colectomy, but is persistent in others. This may have implications for our understanding of ISTC.
authors.affiliation: Department of Coloproctology, Glasgow Royal Infirmary, Glasgow, UK.
authors.forename: D M
authors.initials: DM
authors.lastname: Hemingway
authors.forename: I G
authors.initials: IG
authors.lastname: Finlay
mesh_terms: D000328:Adult; D000714:Anastomosis, Surgical; D003082:Colectomy / Q000379:methods*; D003248:Constipation / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005746:Gastric Emptying / Q000502:physiology*; D006801:Humans; D007082:Ileum / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011300:Preoperative Care; D012007:Rectum / Q000601:surgery; D013997:Time Factors