title: [Lupus anticoagulant in preeclampsia and non-proteinuria gestational hypertension in primiparous women].
abstract: The purpose of this study was to determine the relationship between the lupus anticoagulant and the proteinuric and non-proteinuric Gestational Hypertension in primigravids without subjacent pathology. Sixty- five patients with a single gestation of twenty or more weeks long were studied. Thirty four patients (Group A) were pregnant women with a normal blood pressure. Hypertensive disease developed during pregnancy (according to Davey and MacGillivray, classification) affected 31 patients (Group B). A test to determine the presence of the lupus anticoagulant was performed on all of them, according to the method of the diluted Russel viper venom. None of the patients developed any other symptomatic subjacent pathology. Fifty-five percent of the Group B patients developed proteinuric gestational hypertension (preeclampsia) and forty-five percent of them non-proteinuric gestational hypertension. The test to determine the lupus anticoagulant was negative in all the patients from both groups. The results suggest that the presence of a lupus anticoagulant is unlikely in the proteinuric and non-proteinuric gestational hypertension in primigravidas without subjacent pathology, therefore it remains as a controversial study issue.
authors.affiliation: Hospital General del Sur Dr. Pedro Iturbe, Maracaibo, Venezuela.
authors.forename: G
authors.initials: G
authors.lastname: Arismendi Morillo
authors.forename: M
authors.initials: M
authors.lastname: Fernández-Abreu
authors.forename: L
authors.initials: L
authors.lastname: Alvarez
authors.forename: R
authors.initials: R
authors.lastname: Añez-Moreno
authors.forename: Z
authors.initials: Z
authors.lastname: Bucobo
authors.forename: M
authors.initials: M
authors.lastname: Diez-Ewald
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood*; D016682:Lupus Coagulation Inhibitor / Q000097:blood*; D010298:Parity; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D011446:Prospective Studies; D011507:Proteinuria / Q000097:blood*
chemical_list: D016682:Lupus Coagulation Inhibitor