title: Gene therapy.
abstract: Gene therapy represents a fundamentally new way to treat disease. Originally conceived as an approach to hereditary disease, it is now being applied to a broad range of acquired conditions such as infections, cancers, and degenerative disorders. A current overview of gene therapy is presented in this article, including descriptions of two clinical protocols and perspectives for new directions.
authors.affiliation: Clinical Gene Therapy Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Fibison
mesh_terms: D015316:Genetic Therapy / Q000379:methods / Q000451:nursing; D005822:Genetic Vectors; D006801:Humans; D009369:Neoplasms / Q000235:genetics / Q000628:therapy; D018579:Patient Selection; D012449:Safety; D016511:Severe Combined Immunodeficiency / Q000235:genetics / Q000628:therapy