Blood stem-cell transplantation for chronic active Epstein-Barr virus with lymphoproliferation.
A boy with chronic active Epstein-Barr virus infection (EBV) developed bilateral exophthalmos by infiltrating EBV-infected natural-killer cells during combined chemotherapy. This unusual presentation resolved completely after allogeneic bone-marrow transplantation, and EBV-infected peripheral T and natural-killer cells were also eradicated.
Okamura
T
T
Hatsukawa
Y
Y
Arai
H
H
Inoue
M
M
Kawa
K
K
D000998:Antiviral Agents / Q000627:therapeutic use; D016026:Bone Marrow Transplantation; D002648:Child; D002908:Chronic Disease; D020031:Epstein-Barr Virus Infections / Q000628:therapy*; D005094:Exophthalmos / Q000821:virology; D005938:Glucocorticoids / Q000627:therapeutic use; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007694:Killer Cells, Natural / Q000821:virology; D008232:Lymphoproliferative Disorders / Q000628:therapy / Q000821:virology*; D008297:Male; D009801:Oculomotor Muscles / Q000821:virology; D013601:T-Lymphocytes / Q000821:virology; D019172:Transplantation Conditioning; D014184:Transplantation, Homologous
D000998:Antiviral Agents; D005938:Glucocorticoids; D007166:Immunosuppressive Agents