title: [Insulin-receptor gene polymorphism in type 2 diabetic patients].
abstract: The aim of this study was the assessment of the association of human insulin receptor gene NsiI polymorphism with type 2 diabetes in 125 diabetic patients and 110 healthy individuals. These polymorphism were studied using polymerase chain reaction. It was found the association between N2N2 genotype and type 2 diabetes in patients with normal body weight and with positive family history. The association of the susceptibility to myocardial infarction with N2N2 genotype was also observed.
authors.affiliation: I Katedra i Klinika Chorób Wewnetrznych AM w Lublinie.
authors.forename: A
authors.initials: A
authors.lastname: Puźniak
mesh_terms: D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D005260:Female; D015870:Gene Expression; D020022:Genetic Predisposition to Disease; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000379:methods; D011110:Polymorphism, Genetic / Q000235:genetics*; D011972:Receptor, Insulin / Q000235:genetics*; D012189:Retrospective Studies
chemical_list: D011972:Receptor, Insulin