[Synaptic plasticity and neuromodulation of local cortical connections].
Long-term potentiation (LTP) and long-term depression (LTD) represent two forms of synaptic plasticity which may act as mechanisms for reorganizations of adult mammalian motor cortex. Layer II/III horizontal connections may form a substrate for these reorganizations. The induction of LTP in these connections requires conjoint activation of cortical layer V or layer I. The activity of the cholinergic system facilitates LTP induction.
Hess
G
G
Instytut Zoologii Uniwersytetu Jagiellońskiego w Krakowie. Hess@zuk.iz.uj.edu.pl
D000109:Acetylcholine / Q000378:metabolism; D000328:Adult; D006801:Humans; D017774:Long-Term Potentiation / Q000502:physiology; D009415:Nerve Net / Q000378:metabolism / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology*; D013569:Synapses / Q000378:metabolism / Q000502:physiology*
D000109:Acetylcholine