title: Paeonilide, a novel anti-PAF-active monoterpenoid-derived metabolite from Paeonia delavayi.
abstract: A novel monoterpenoid-derived metabolite, paeonilide, was isolated from the roots of Paeonia delavayi. Its structure was established by a combination of spectroscopic and X-ray crystallographic analyses. It showed an anti-PAF effect with an IC50 value of ca. 8 microg/ml.
authors.affiliation: Department of Phytochemistry, Kunming Institute of Botany, The Chinese Academy of Sciences, P.R. China. jkl@public.km.yn.cn
authors.forename: J K
authors.initials: JK
authors.lastname: Liu
authors.forename: Y B
authors.initials: YB
authors.lastname: Ma
authors.forename: D G
authors.initials: DG
authors.lastname: Wu
authors.forename: Y
authors.initials: Y
authors.lastname: Lu
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Shen
authors.forename: Q T
authors.initials: QT
authors.lastname: Zheng
authors.forename: Z H
authors.initials: ZH
authors.lastname: Chen
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000378:metabolism; D008968:Molecular Conformation; D018517:Plant Roots / Q000737:chemistry / Q000378:metabolism; D010946:Plants, Medicinal / Q000737:chemistry* / Q000378:metabolism; D010972:Platelet Activating Factor / Q000037:antagonists & inhibitors*; D010975:Platelet Aggregation Inhibitors / Q000737:chemistry* / Q000145:classification / Q000302:isolation & purification; D013729:Terpenes / Q000737:chemistry* / Q000145:classification / Q000302:isolation & purification
chemical_list: D004365:Drugs, Chinese Herbal; D010972:Platelet Activating Factor; D010975:Platelet Aggregation Inhibitors; D013729:Terpenes; C416702:paeonilide