title: Congenital heart disease. Evaluation of anatomy and function by MRI.
abstract: With the increasing number of patients surviving after therapeutic intervention for congenital heart disease (CHD), accurate and frequent follow-up of their morphologic and functional cardiovascular status is required, preferably with a noninvasive imaging technique. Echocardiography, either transthoracic or transesophageal, has been the first choice for this purpose, and will probably keep that status, at least in a large segment of the CHD spectrum. Magnetic resonance imaging (MRI) is an established method for high-resolution visualization of cardiovascular morphology. In the past decade, newer MRI techniques have been developed that allow functional evaluation of CHD patients. Particularly the introduction of breath-hold imaging, contrast-enhanced MRA and user-friendly computer software for image analysis may move functional MRI of CHD from the science laboratory to clinical use. It is already evident that MRI is superior to echocardiography in certain areas of limited echocardiographic access, such as the pulmonary artery branches and the aortic arch in adult patients. But MRI has also a unique potential for accurate volumetric analysis of ventricular function and cardiovascular blood flow, without any geometric assumptions. If supported by increased cooperation between cardiologists and radiologists, MRI will grow into a useful noninvasive imaging tool that, together with echocardiography, will obviate the need for invasive catheter studies for diagnostic purposes.
authors.affiliation: Department of Radiology, Leiden University Medical Center, The Netherlands. s.a.rebergen@lumc.nl
authors.forename: S A
authors.initials: SA
authors.lastname: Rebergen
authors.forename: A
authors.initials: A
authors.lastname: de Roos
mesh_terms: D000328:Adult; D001017:Aortic Coarctation / Q000175:diagnosis; D016122:Brachiocephalic Trunk / Q000002:abnormalities; D002648:Child; D003287:Contrast Media; D004452:Echocardiography; D005069:Evaluation Studies as Topic; D006330:Heart Defects, Congenital / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D006343:Heart Septal Defects / Q000175:diagnosis; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008382:Marfan Syndrome / Q000175:diagnosis; D018633:Pulmonary Atresia / Q000175:diagnosis; D011666:Pulmonary Valve Stenosis / Q000175:diagnosis; D013902:Radiography, Thoracic; D013771:Tetralogy of Fallot / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D014188:Transposition of Great Vessels / Q000175:diagnosis
chemical_list: D003287:Contrast Media