Genetic polymorphism of group-specific component/vitamin-D-binding protein subtypes in six populations from north-eastern China.
On six populations from North-Eastern China the frequencies of Gc subtypes were studied by isoelectric focusing on ultra-thin polyacrylamidegel followed by the improved sulfosalicylic acid precipitation. The following Gc subtype allele frequencies could be observed in the Han (Harbin), Ewenki, Tahur, Mongolian, Oroquen and Xibe populations: Gc*1F = 0.4246, 0.4941, 0.4479, 0.4077, 0.4606 and 0.4503; Gc*1S = 0.2587, 0.2936, 0.3151, 0.2822, 0.3370 and 0.3035; Gc*2 = 0.3065, 0.2064, 0.2266, 0.3006, 0.2022 and 0.2388. In addition to this 16 individuals of five populations showed rare Gc variant alleles (1A3, 1A8, 1A9, 1A14, 1C?).
Yin
J
J
Department of Medical Genetics, Shenyang Medical College, China.
Zhang
G
G
Liu
J
J
D000483:Alleles; D002681:China; D005787:Gene Frequency; D014644:Genetic Variation / Q000235:genetics; D005828:Genetics, Population; D006801:Humans; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*; D014809:Vitamin D-Binding Protein / Q000235:genetics*
D014809:Vitamin D-Binding Protein