Nonracemic 2-diazo-1-oxiranyl-ethanone, a versatile chiral epoxide educt in diazocarbonyl reactions
(S)-(-)-2-Diazo-1-oxiranyl-ethanone, prepared in two steps from (R)-(+)-glycidol, has been employed as an intermediate in several characteristic diazocarbonyl reactions to yield novel, nonracemic products including an epoxy quinoxaline and epoxy thiazoles and oxazoles.
Groarke
M
School of Chemistry, The Queen's University, Belfast BT9 5AG, Northern Ireland.
McKervey
MA
Miel
H
Nieuwenhuyzen
M