[Variability in the MR tomographic determination of myocardial function and perfusion parameters in health subjects].
OBJECTIVE
The aim of the study was to evaluate myocardial function and perfusion patterns using magnetic resonance imaging in normal subjects.


METHODS
22 healthy volunteers were examined. Cine-mode acquisitions along all three axes of the heart were generated and perfusion was measured on a mid-ventricular short-axis view. Myocardial wall thickening was scored and contrast enhancement during the first pass was analysed.


RESULTS
For myocardial wall thickening increasing values from base (24-86%) to apex (63-106%) were found. Contrast enhancement patterns showed regional variability. In addition marked individual differences were detectable.


CONCLUSIONS
Perfusion patterns should be interpreted only in combination with functional parameters. Standard values for perfusion measurements cover very large range as a result of the high individual variability.
Kramer
U
U
Universitätsklinik Tübingen, Abteilung Radiologische Diagnostik. ulrich.kramer@med.uni-tuebingen.de
Miller
S
S
Helber
U
U
Schick
F
F
Nägele
T
T
Brechtel
K
K
Huppert
P
P
Claussen
C D
CD
D000328:Adult; D003287:Contrast Media; D005260:Female; D006321:Heart / Q000033:anatomy & histology* / Q000502:physiology*; D006334:Heart Function Tests; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010477:Perfusion; D012016:Reference Values
D003287:Contrast Media