title: C-Difluoromethylene-containing, C-trifluoromethyl and C-perfluoroalkyl carbohydrates. Synthesis by carbohydrate transformation or building block methods.
abstract: The synthetic methods for preparing carbohydrates bearing a C-branched substituent of the type CF2-Y, with Y = F, Y = CnF(2n + 1) or Y = a carbon-attached or heteroatom-attached nonfluorinated residues, are reviewed. Both direct introduction of C-branched fluorinated substituents (direct trifluoromethylation, perfluoroalkylation or difluoromethylenation) and building block methods from fluorinated synthons are considered.
authors.affiliation: Laboratoire Réactions Sélectives et Applications, Associé au CNRS (UMR 6519), Université de Reims, Facult des Sciences, France.
authors.forename: R
authors.initials: R
authors.lastname: Plantier-Royon
authors.forename: C
authors.initials: C
authors.lastname: Portella
mesh_terms: D002241:Carbohydrates / Q000138:chemical synthesis / Q000737:chemistry*; D005461:Fluorine / Q000737:chemistry*; D005466:Fluorocarbons / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D002241:Carbohydrates; D005466:Fluorocarbons; D005461:Fluorine