Positive relationship between menstrual synchrony and ability to smell 5alpha-androst-16-en-3alpha-ol.
To explore the possibility that compounds which were identified as pheromones in experimental animals mediate human menstrual synchrony, we examined the relationship between menstrual synchrony and the ability to smell putative pheromones, 5alpha-androst-16-en-3alpha-ol (3alpha-androstenol) and 5alpha-androst-16-en-3-one (5alpha-androstenone). When we examined menstrual synchrony among 64 women living together in a college dormitory, we found that 24 (38%) of them became synchronized with room-mates in 3 months. Afterwards, dilution series of 3alpha-androstenol and 5alpha-androstenone and the control odorant (pyridine) were presented to the 64 women and sensitivity to the odors was compared between synchronized and non-synchronized women. No difference was found between the two groups of women in the detection threshold for pyridine, indicating that general olfactory ability did not differ between them. The detection threshold for 3alpha-androstenol of synchronized women was significantly lower than that of non-synchronized women, but no difference in the threshold for 5alpha-androstenone was found between synchronized and non-synchronized women. These results indicate that the women who showed menstrual synchrony had a higher sensitivity to 3alpha-androstenol but not necessarily to 5alpha-androstenone.
Morofushi
M
M
Department of Physiology, Yokohama City University School of Medicine, Yokohama 236-0004, Japan.
Shinohara
K
K
Funabashi
T
T
Kimura
F
F
D000736:Androstenes / Q000032:analysis; D000737:Androstenols / Q000032:analysis; D005260:Female; D006801:Humans; D008598:Menstruation / Q000502:physiology*; D010675:Pheromones / Q000032:analysis*; D012684:Sensory Thresholds; D012903:Smell / Q000502:physiology*
D000736:Androstenes; D000737:Androstenols; D010675:Pheromones; C003530:androst-16-en-3-ol; C000214:androst-16-en-3-one