title: Schnitzler's syndrome: no evidence for autoimmune basis in two patients.
abstract: We report two cases of Schnitzler's syndrome in which anti-interleukin-1alpha autoantibodies and functional autoantibodies against the high affinity IgE receptor (FcepsilonRIalpha) or against IgE were absent. One patient responded well to TL-01 phototherapy, a treatment which may be considered in patients with Schnitzler's syndrome if, as is usually the case, they are unresponsive to antihistamine therapy.
authors.affiliation: Professorial Unit, St. John's Institute of Dermatology, St. Thomas's Hospital, London, UK.
authors.forename: R
authors.initials: R
authors.lastname: Gallo
authors.forename: R A
authors.initials: RA
authors.lastname: Sabroe
authors.forename: A K
authors.initials: AK
authors.lastname: Black
authors.forename: M W
authors.initials: MW
authors.lastname: Greaves
mesh_terms: D000368:Aged; D001323:Autoantibodies / Q000097:blood*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007375:Interleukin-1 / Q000276:immunology*; D008875:Middle Aged; D010789:Phototherapy; D017455:Receptors, IgE / Q000276:immunology; D019873:Schnitzler Syndrome / Q000276:immunology* / Q000628:therapy; D016896:Treatment Outcome; D016312:Treatment Refusal
chemical_list: D001323:Autoantibodies; D007375:Interleukin-1; D017455:Receptors, IgE; D007073:Immunoglobulin E