title: The feasibility and accuracy of diagnostic laparoscopy in the septic ICU patient.
abstract: BACKGROUND
  Systemic inflammatory response syndrome (SIRS) and sepsis of unknown origin are common complications of critically ill patients in the ICU. These patients frequently have unreliable clinical exams and are candidates for exploratory laparotomy. Although abdominal CT is commonly used because it is less invasive than laparotomy, it is often unreliable or unobtainable. Bedside laparoscopy is an alternative technique that may be more accurate than CT in selected patients and less invasive than laparotomy.
  
  
  METHODS
  We performed diagnostic laparoscopy (DL) in a series of ICU patients with SIRS/septic state of unknown origin between May 1997 and June 1998. All patients were unstable and required significant respiratory and hemodynamic support. Laparoscopy was either performed in the ICU at the patient's bedside or in the operating room. CT scan of the abdomen had been performed on most of the patients who were stable enough to transport. Confirmation of diagnosis was obtained either by laparotomy, autopsy, or clinical recovery.
  
  
  RESULTS
  Among the 17 eligible patients, 16 underwent successful DL. Insufflation was impossible in one patient because of high intraabdominal pressure. Bedside evaluations were performed in 14 of the 17 patients. There were no complications from the laparoscopy. Six patients were identified as positive (four intestinal ischemia, two cholecystitis); the other 10 had negative explorations. Follow-up on two patients with negative laparoscopy was incomplete due to denied postmortem. Laparoscopic diagnoses were confirmed in the remaining 14 patients by laparotomy (six cases), postmortem (three cases), or recovery (five cases), with an accuracy of 100%. The overall accuracy of abdominal CT obtained in nine of the 14 patients was 33%.
  
  
  CONCLUSIONS
  DL in a select group of critical ICU patients is safe and accurate, whereas CT scan tends to be inaccurate and is often unobtainable due to patient instability. Performing the procedure at the bedside can expedite the diagnosis, eliminate the burden for transfer, and save on anesthesia and operating room charges.
authors.affiliation: Department of Surgery, University of Massachusetts Medical School, Worcester 01605, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Kelly
authors.forename: J C
authors.initials: JC
authors.lastname: Puyana
authors.forename: M P
authors.initials: MP
authors.lastname: Callery
authors.forename: S M
authors.initials: SM
authors.lastname: Yood
authors.forename: A
authors.initials: A
authors.lastname: Sandor
authors.forename: D E
authors.initials: DE
authors.lastname: Litwin
mesh_terms: D005240:Feasibility Studies; D006801:Humans; D007362:Intensive Care Units; D010535:Laparoscopy; D011446:Prospective Studies; D015203:Reproducibility of Results; D018746:Systemic Inflammatory Response Syndrome / Q000175:diagnosis* / Q000209:etiology