title: Genetics. L1 retrotransposons shape the mammalian genome.
abstract: What are all of those retrotransposons doing buzzing about in our genome? According to Kazazian, in his Perspective this week, these mobile pieces of DNA are busy reshaping our genome, making it more diverse and enabling us to survive and thrive through the vagaries of evolution. And just how do they do this?...zip to page 1152 to find out.
authors.affiliation: Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. kazazian@mail.med.upenn.edu
authors.forename: H H
authors.initials: HH
authors.lastname: Kazazian
mesh_terms: D020087:Alu Elements; D000818:Animals; D004303:Dosage Compensation, Genetic; D016678:Genome; D015894:Genome, Human; D006801:Humans; D020084:Long Interspersed Nucleotide Elements; D008322:Mammals / Q000235:genetics*; D016254:Mutagenesis, Insertional; D011544:Pseudogenes; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D018626:Retroelements; D019098:Telomerase / Q000737:chemistry / Q000235:genetics; D020079:Terminal Repeat Sequences
chemical_list: D012333:RNA, Messenger; D018626:Retroelements; D019098:Telomerase