title: Quality control limits for broth microdilution susceptibility tests of ten antifungal agents.
abstract: Broth microdilution susceptibility tests of Candida species have now been standardized by the National Committee for Clinical Laboratory Standards (NCCLS). An eight-laboratory collaborative study was carried out in order to document reproducibility of tests of Candida parapsilosis ATCC 22019 and Candida krusei ATCC 6258 by the NCCLS method. Replicate broth microdilution tests were used to define control limits for 24- and 48-h MICs of amphotericin B, flucytosine, fluconazole, voriconazole, ketoconazole, itraconazole, caspofungin (MK 0991), ravuconazole (BMS 207147), posaconazole (SCH 56592), and LY 303366.
authors.affiliation: The Clinical Microbiology Institute, Wilsonville, Oregon. cmi@hevanet.com
authors.forename: A L
authors.initials: AL
authors.lastname: Barry
authors.forename: M A
authors.initials: MA
authors.lastname: Pfaller
authors.forename: S D
authors.initials: SD
authors.lastname: Brown
authors.forename: A
authors.initials: A
authors.lastname: Espinel-Ingroff
authors.forename: M A
authors.initials: MA
authors.lastname: Ghannoum
authors.forename: C
authors.initials: C
authors.lastname: Knapp
authors.forename: R P
authors.initials: RP
authors.lastname: Rennie
authors.forename: J H
authors.initials: JH
authors.lastname: Rex
authors.forename: M G
authors.initials: MG
authors.lastname: Rinaldi
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects*; D007753:Laboratories / Q000592:standards*; D008826:Microbial Sensitivity Tests / Q000379:methods / Q000592:standards*; D011786:Quality Control; D015203:Reproducibility of Results
chemical_list: D000935:Antifungal Agents