In vivo 1H-magnetic resonance spectroscopy of the spinal cord in humans.
Magnetic resonance spectroscopy (MRS) has been used in a variety of conditions affecting the central nervous system. Until now, only the brain has been studied, and spectroscopy of the spinal cord has not been previously reported. During the past 12 months, we have been experimenting with MRS of the cervical spinal cord of healthy volunteers. We present this technique, its current limitations, and possible future technological improvements and potential applications.
Gómez-Ansón
B
B
NMR Research Unit, Institute of Neurology, University College London, UK. bg219@wbic.cam.ac.uk
MacManus
D G
DG
Parker
G J
GJ
Davie
C A
CA
Barker
G J
GJ
Moseley
I F
IF
McDonald
W I
WI
Miller
D H
DH
D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000378:metabolism; D002574:Cervical Vertebrae; D002794:Choline / Q000378:metabolism; D003401:Creatine / Q000378:metabolism; D004734:Energy Metabolism / Q000502:physiology*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D012016:Reference Values; D013116:Spinal Cord / Q000503:physiopathology; D013118:Spinal Cord Diseases / Q000175:diagnosis* / Q000503:physiopathology
D001224:Aspartic Acid; C000179:N-acetylaspartate; D003401:Creatine; D002794:Choline