Beckwith-Wiedemann syndrome and virilizing cortical adrenal tumor in a child.
The authors report a case of a virilizing adrenal tumor that developed in a 2-year-old child with Beckwith-Wiedemann syndrome (BWS). He had a fetal diagnosis of omphalocele and a history of neonatal adrenal cysts. The importance of prenatal diagnosis of BWS and postnatal follow-up of tumors is discussed. The differential diagnosis of adrenal pathologies occurring in BWS also is reviewed.
Sbragia-Neto
L
L
Department of Pathology, Faculty of Medical Science, State University of Campinas, São Paulo, Brazil.
Melo-Filho
A A
AA
Guerra-Júnior
G
G
Valente de Lemos Marini
S H
SH
Baptista
M T
MT
Sabino de Matos
P S
PS
Gonçalves de Oliveira-Filho
A
A
Bustorff-Silva
J M
JM
D000306:Adrenal Cortex Neoplasms / Q000150:complications* / Q000175:diagnosis; D001506:Beckwith-Wiedemann Syndrome / Q000150:complications* / Q000175:diagnosis; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011296:Prenatal Diagnosis; D013997:Time Factors; D014770:Virilism / Q000209:etiology