Indium-111 platelet scintigraphy in a patient with chronic disseminated intravascular coagulation.
The authors describe a relation between the in vivo localized consumption of In-111 platelets and results of laboratory tests in a 82-year-old man with an aortic graft prosthesis who had chronic disseminated intravascular coagulation. In-111 platelets accumulated markedly over the abdominal aortic graft with a shortened platelet survival time and reflected changes in hematologic studies, which showed low platelet counts and a high concentration of fibrinogen degradation products in the plasma. If a strong clinical likelihood of local disseminated intravascular coagulation exists, then In-111 platelets may be valuable in localizing the focus of platelet consumption.
Nakanishi
E
E
Department of Internal Medicine, Osaka National Hospital, Japan.
Isaka
Y
Y
Etani
H
H
Furukawa
S
S
Ooe
Y
Y
Imaizumi
M
M
D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery; D001792:Blood Platelets; D001807:Blood Vessel Prosthesis / Q000009:adverse effects; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects; D002908:Chronic Disease; D004211:Disseminated Intravascular Coagulation / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D010974:Platelet Aggregation; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D010976:Platelet Count; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013499:Surface Properties
D005338:Fibrin Fibrinogen Degradation Products; D007205:Indium Radioisotopes; D010975:Platelet Aggregation Inhibitors; D019275:Radiopharmaceuticals