New allene synthesis via carbocupration-zinc carbenoid homologation and beta-elimination sequence.
[reaction: see text] Polysubstituted propadienes are obtained in good to excellent yields by the consecutive carbocupration-homologation-beta-elimination reactions on the easily accessible alkynyl sulfoxides or sulfones. This one-pot reaction also allows the preparation of functionalized allenes.
Varghese
J P
JP
Department of Chemistry and Institute of Catalysis Science and Technology, Technion-Israel Institute of Technology, Technion City, 32000 Haifa, Israel.
Knochel
P
P
Marek
I
I