[Neoformed multiple hepatic angiomas after exposure to vinyl chloride monomer: report of a case].
The paper describes the case of a 60 years old man with previous protracted exposure to CVM. After a latency of 20 years, the man developed two hepatic hemangiomas, one characterized by rapid growth (4 cm of diameter in 1 year) and surgically removed. On the basis of the anamnestic data (15 years in a PVC polymerization factory in the reactor vessels department) considering the degree and duration of exposure to CVM, an occupational origin of the hepatic hemangiomas is probable. The ability of CVM to induce sclerosis, necrosis and endothelial hyperplasy in the liver tissue may represent the primum movens of hemangiomas.
Borchini
R
R
Scuola di Specializzazione di Medicina del Lavoro, Università degli Studi di Milano, Clinica del Lavoro L. Devoto.
Riboldi
L
L
Chiappino
G
G
D002273:Carcinogens / Q000009:adverse effects*; D006391:Hemangioma / Q000139:chemically induced*; D006801:Humans; D008113:Liver Neoplasms / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D014752:Vinyl Chloride / Q000009:adverse effects*
D002273:Carcinogens; D014752:Vinyl Chloride