title: Phytosulfokine-alpha, a peptide growth factor found in higher plants: its structure, functions, precursor and receptors.
abstract: Phytosulfokine-alpha, a sulfated pentapeptide growth factor universally found in both monocotyledons and dicotyledons, strongly promotes proliferation of plant cells in culture. It is similar to animal polypeptide hormones in that it is processed from a larger precursor, preprophytosulfokine, although the putative processing sites do not conform to consensus sequences for endoproteolytic processing sites flanking animal prohormones. Like the animal preprohormones, preprophytosulfokine also has a signal peptide at the N-terminus for targeting to secretory pathways. The preprophytosulfokine gene has been confirmed to be expressed in vivo as well as in vitro.
authors.affiliation: Laboratory of Bioactive Natural Product Chemistry, Graduate School of Bio-Agricultural Sciences, Nagoya University, Aichi, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yang
authors.forename: Y
authors.initials: Y
authors.lastname: Matsubayashi
authors.forename: H
authors.initials: H
authors.lastname: Hanai
authors.forename: Y
authors.initials: Y
authors.lastname: Sakagami
mesh_terms: D000595:Amino Acid Sequence; D006133:Growth Substances / Q000737:chemistry* / Q000378:metabolism*; D008969:Molecular Sequence Data; D036361:Peptide Hormones; D010937:Plant Growth Regulators; D010940:Plant Proteins / Q000737:chemistry* / Q000378:metabolism*; D010944:Plants / Q000378:metabolism*; D011956:Receptors, Cell Surface / Q000378:metabolism*
chemical_list: D006133:Growth Substances; C100975:PSK-alpha protein, plant; D036361:Peptide Hormones; D010937:Plant Growth Regulators; D010940:Plant Proteins; D011956:Receptors, Cell Surface; C409473:phytosulfokine-alpha receptor, plant