Synthesis and systemic fungicidal activity of silicon-containing azole derivatives.
A new series of azole derivatives containing silicon were synthesized and evaluated for fungicidal activity against rice sheath blight by submerged application. Among them, 2-(4-fluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-trimethylsilylpr opan-2-ol (9a) exhibited satisfactory efficacy at 12.5 grams per 10 ares.
Itoh
H
H
Agroscience Research Laboratories, Sankyo Co., Ltd., Siga, Japan. hiroit@yasu.sankyo.co.jp
Yoneda
R
R
Tobitsuka
J
J
Matsuhisa
T
T
Kajino
H
H
Ohta
H
H
Hayashi
N
N
Takahi
Y
Y
Tsuda
M
M
Takeshiba
H
H
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001393:Azoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012275:Oryza / Q000382:microbiology; D012232:Rhizoctonia / Q000187:drug effects; D012825:Silicon / Q000737:chemistry*
D000935:Antifungal Agents; D001393:Azoles; D012825:Silicon