title: Tympanic membrane and middle ear pathologic correlates in mucoid otitis media.
abstract: OBJECTIVE
  The goal of this study was to correlate tympanic membrane (TM) and middle ear (ME) pathologies in mucoid otitis media (MOM).
  
  
  METHODS
  Forty ears with MOM and 56 control ears were retrospectively evaluated for TM and ME pathologies. Comparisons of TM thicknesses in MOM versus control ears were correlated with the Student t test; chi(2) analysis was used to correlate pathologic findings of the TM and ME.
  
  
  RESULTS
  Thicknesses in all quadrants except the umbo were increased in MOM because of infiltration of inflammatory cells and fibrosis. The most common ME pathologies were granulation tissue and fibrosis. Significant correlations included (1) TM retraction and ME granulation tissue and fibrosis and (2) pars flaccida, posterosuperior, and anteroinferior thickness and ME granulation tissue and fibrosis.
  
  
  CONCLUSIONS
  TM changes are likely to occur in patients with otitis media with effusion (MOM), and their presence is a strong indication of underlying ME pathology.
authors.affiliation: Otitis Media Research Center, Department of Otolaryngology, University of Minnesota Medical School, Minneapolis, USA.
authors.forename: M
authors.initials: M
authors.lastname: Tekin
authors.forename: C
authors.initials: C
authors.lastname: Mutlu
authors.forename: M M
authors.initials: MM
authors.lastname: Paparella
authors.forename: P A
authors.initials: PA
authors.lastname: Schachern
authors.forename: V J
authors.initials: VJ
authors.lastname: Jaisinghani
authors.forename: C T
authors.initials: CT
authors.lastname: Le
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D004432:Ear, Middle / Q000473:pathology*; D005355:Fibrosis; D006097:Granulation Tissue / Q000473:pathology; D006801:Humans; D007223:Infant; D008875:Middle Aged; D010033:Otitis Media / Q000473:pathology*; D014432:Tympanic Membrane / Q000473:pathology*