Synthesis and absolute configuration of hongoquercin B, a sesquiterpene-substituted orsellinic acid isolated as a fungal metabolite.
(+)-Hongoquercin B (1), a weakly antibacterial fungal metabolite, was synthesized by starting from (S)-3-hydroxy-2,2-dimethylcyclohexanone, and its absolute configuration was determined as depicted by structure 1.
Tsujimori
H
H
Department of Chemistry, Faculty of Science, Science University of Tokyo, Japan.
Mori
K
K
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry*; D003512:Cyclohexanones / Q000737:chemistry; D008968:Molecular Conformation; D012717:Sesquiterpenes / Q000138:chemical synthesis / Q000737:chemistry
D000900:Anti-Bacterial Agents; D003512:Cyclohexanones; D012717:Sesquiterpenes; C114156:hongoquercin B