Behavioural effects of subchronic lead treatment in combination with ethanol in rats.
The effect of lead acetate administration during perinatal (1. prenatal, 2. prenatal and suckling period, 3. prenatal + suckling period + 4 weeks after weaning) development in combination with ethanol was investigated in Wistar rats at the age of 12 weeks on open-field behaviour and auditory startle response. Lead intoxication has on the investigated behavioural parameters the most pronouncing effect when applied during the days 5-15 of pregnancy.
Schulz
H
H
Department of Public Health, Albert Szent-Györgyi Medical University, Szeged, Hungary. sch@puhe.szote.u-szeged.hu
Nagymajtényi
L
L
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D005314:Embryonic and Fetal Development / Q000187:drug effects; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D006624:Hippocampus / Q000187:drug effects / Q000196:embryology / Q000378:metabolism; D007854:Lead / Q000633:toxicity*; D017774:Long-Term Potentiation / Q000187:drug effects; D008297:Male; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar
D007854:Lead; D000431:Ethanol