Interactions between Listeria monocytogenes and host mammalian cells.
Bacterial pathogens have developed a variety of strategies to induce their own internalization into mammalian cells which are normally nonphagocytic. The Gram-positive bacterium Listeria monocytogenes enters into many cultured cell types using two bacterial surface proteins, InlA (internalin) and InlB. In both cases, entry takes place after engagement of a receptor and induction of a series of signaling events.
Braun
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Unité des interactions bactéries-cellules, Institut Pasteur, 28, Paris, France.
Cossart
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D000818:Animals; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015820:Cadherins / Q000378:metabolism; D006801:Humans; D008089:Listeria monocytogenes / Q000378:metabolism / Q000472:pathogenicity* / Q000502:physiology; D008322:Mammals; D008565:Membrane Proteins / Q000737:chemistry / Q000378:metabolism; D005810:Multigene Family; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D015398:Signal Transduction
D001426:Bacterial Proteins; D015820:Cadherins; D008565:Membrane Proteins; C095768:inlB protein, Listeria monocytogenes; C069761:internalin protein, Bacteria; D019869:Phosphatidylinositol 3-Kinases