Breast-cancer diagnosis with nipple fluid bFGF.
Early diagnosis of breast cancer is the key to extending survival of breast-cancer patients. We found that the concentrations of nipple fluid bFGF (basic fibroblast growth factor) was significantly increased in breast-cancer patients compared with concentrations in controls (1717 ng/L [SD 706] vs 19 ng/L [19]; Student's t test p=0.027). Measurement of bFGF in nipple fluid could be a useful diagnostic tool for breast cancer, and deserves further study.
Liu
Y
Y
Wang
J L
JL
Chang
H
H
Barsky
S H
SH
Nguyen
M
M
D014408:Biomarkers, Tumor / Q000032:analysis; D001826:Body Fluids / Q000737:chemistry*; D001943:Breast Neoplasms / Q000175:diagnosis*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016222:Fibroblast Growth Factor 2 / Q000032:analysis*; D006801:Humans; D009558:Nipples / Q000378:metabolism*
D014408:Biomarkers, Tumor; D016222:Fibroblast Growth Factor 2