Psychiatric presentation of Huntington's disease in a Malaysian family.
A 32-year-old Chinese lady presented to the Psychiatric Clinic with a history of change in personality for 2 years and abnormal movements for a year. After thorough investigations and observation a diagnosis of Huntington's Disease was made. Her elder brother was traced and found to have Huntington's Disease as well. He had a long standing history of antisocial behaviour and substance abuse long before the onset of the choreiform movements. Her younger brother also has choreiform movements for the last 2 years and had recent change in personality. Their mother also had abnormal movements and was recorded to be depressed and attempted suicide. The maternal grandfather had a mental illness and was warded at a mental institution till his death in 1942. Psychiatric presentation of Huntington's Disease in this Malaysian family is prominent and preceded the characteristic movements in the present generation.
Chin
C N
CN
Department of Psychiatry, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur.
S'ng
K H
KH
Philip
G
G
Rosdinom
R
R
Wahidah
A
A
D000328:Adult; D003863:Depression / Q000209:etiology*; D005260:Female; D006801:Humans; D006816:Huntington Disease / Q000235:genetics* / Q000523:psychology*; D008296:Malaysia; D008297:Male; D008875:Middle Aged