title: Primary biliary cirrhosis associated with idiopathic retroperitoneal fibrosis.
abstract: Idiopathic retroperitoneal fibrosis (IRF) and primary biliary cirrhosis (PBC) are distinct clinical disorders which rarely occur in the same patient. We report a 79-year-old man with the coexistence of both conditions. The patient had antibodies to both centromere and mitochondria, as indicated by indirect immunofluorescence. Diagnoses of IRF and PBC were confirmed histologically. Although the association between IRF and PBC is obscure, IRF may be involved in many autoimmune diseases associated with PBC.
authors.affiliation: Department of Internal Medicine, Nagasaki Chuo National Hospital, Omura, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Shikuwa-
authors.forename: K
authors.initials: K
authors.lastname: Omagari
authors.forename: Y
authors.initials: Y
authors.lastname: Mizuta
authors.forename: K
authors.initials: K
authors.lastname: Murase
authors.forename: M
authors.initials: M
authors.lastname: Osabe
authors.forename: M
authors.initials: M
authors.lastname: Yoshimura
authors.forename: M
authors.initials: M
authors.lastname: Ohfukuji
authors.forename: Y
authors.initials: Y
authors.lastname: Takehara
authors.forename: H
authors.initials: H
authors.lastname: Isomoto
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: I
authors.initials: I
authors.lastname: Shimokawa
authors.forename: S
authors.initials: S
authors.lastname: Kohno
mesh_terms: D000368:Aged; D019268:Antibodies, Antineutrophil Cytoplasmic; D000974:Antibodies, Antinuclear / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D002503:Centromere / Q000276:immunology; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008928:Mitochondria / Q000276:immunology; D012185:Retroperitoneal Fibrosis / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000473:pathology
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D000974:Antibodies, Antinuclear; D001323:Autoantibodies