title: Multiple endocrine neoplasia type 1.
abstract: The recent cloning of the gene responsible for multiple endocrine neoplasia type 1 (MEN 1) has opened new avenues for both clinical and basic science research in the field of endocrine oncology. A large amount of genetic information, particularly those in relation to germline and somatic mutations, has since been published during the last 2 years. This new knowledge has provided important insights into its gene function. The significance of these advances in relation to clinical management and future directions for research is discussed.
authors.affiliation: Department of Molecular Medicine, CMM L8:01, Karolinska Hospital, Stockholm, S-17176, Sweden.
authors.forename: F
authors.initials: F
authors.lastname: Ki Wong
authors.forename: J
authors.initials: J
authors.lastname: Burgess
authors.forename: M
authors.initials: M
authors.lastname: Nordenskjöld
authors.forename: C
authors.initials: C
authors.lastname: Larsson
authors.forename: B
authors.initials: B
authors.lastname: Tean Teh
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D005838:Genotype; D006801:Humans; D018761:Multiple Endocrine Neoplasia Type 1 / Q000235:genetics*; D009154:Mutation / Q000235:genetics; D009363:Neoplasm Proteins / Q000378:metabolism; D010641:Phenotype; D012307:Risk Factors
chemical_list: D009363:Neoplasm Proteins