HLA-A, HLA-B and HLA-C polymorphism in the Slovak population.
The occurrence rates of class I HLA alleles were investigated in a sample of the Slovak population by a PCR-SSP method. The frequencies of HLA-A alleles ranged from 0.00 for A*4301 to 0.2798 for A*0201-22; the frequencies of HLA-B alleles ranged from 0.00 for B 4601,B* 4801-3, B*5901,B* 7301, and B* 8101 to 0.1101 for B* 4402-10, and those of HLA-C alleles from 0.00 for Cw*1301 and Cw* 1402-3 to 0.2661 for Cw 0701-10. The occurrence rates of class I HLA alleles established in our study were compared with those in the Czech population. No significant differences were found.
Kulcsárová
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Department of Immunology, School of Medicine, Comenius University, Bratislava, Slovakia. kulcsarova@hotmail.com
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Ferencik
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D000483:Alleles; D004247:DNA / Q000097:blood; D004587:Electrophoresis, Agar Gel; D005787:Gene Frequency; D005805:Genes, MHC Class I; D015234:HLA-A Antigens / Q000235:genetics*; D015235:HLA-B Antigens / Q000235:genetics*; D015236:HLA-C Antigens / Q000235:genetics*; D006801:Humans; D016133:Polymerase Chain Reaction / Q000379:methods; D011110:Polymorphism, Genetic; D018154:Slovakia
D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D004247:DNA