title: Major metabolites of ginseng sapogenins formed by rat liver microsomes.
abstract: Incubation of ginseng sapogenins with microsomes from rat liver resulted in formation of their 20,24-epoxides as major metabolites. Identification of the metabolites was performed by HPLC, FAB-MS and EI-MS.
authors.affiliation: Institute of Pharmaceutical Sciences, Faculty of Medicine, Hiroshima University, Japan. rkasai@pharm.hiroshima-u.ac.jp
authors.forename: R
authors.initials: R
authors.lastname: Kasai
authors.forename: K
authors.initials: K
authors.lastname: Hara
authors.forename: R
authors.initials: R
authors.lastname: Dokan
authors.forename: N
authors.initials: N
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Mizutare
authors.forename: S
authors.initials: S
authors.lastname: Yoshihara
authors.forename: K
authors.initials: K
authors.lastname: Yamasaki
mesh_terms: D000818:Animals; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D008862:Microsomes, Liver / Q000378:metabolism*; D005894:Panax / Q000378:metabolism*; D010946:Plants, Medicinal; D051381:Rats; D012502:Sapogenins / Q000378:metabolism*
chemical_list: D012502:Sapogenins