Psychoimmune neuroendocrine integrative mechanisms revisited.
This review analyzes recent publications on the topic of psycho-immune-neuroendocrine integrative mechanisms. Results on the role of cytokines in cognitive processes and in a major neuroendocrine event, i.e. the release of gonadotropin-releasing hormone, are discussed, as are the effects of cytokines on central neurotransmission. The control of immune responses by local sympathetic nerves, a major pathway in neuroimmune communication, is discussed. This review also updates information indicating that melatonin is a circulating signal affecting the periodic organization of the immune response.
Cardinali
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DP
Departamento de Fisiología, Facultad de Medicina, Universidad de Buenos Aires, Argentina. cardinal@smail.retina.ar
Cutrera
R A
RA
Esquifino
A I
AI
D000818:Animals; D000917:Antibody Formation / Q000502:physiology; D003071:Cognition / Q000502:physiology*; D016207:Cytokines / Q000502:physiology*; D006801:Humans; D009490:Neurosecretory Systems / Q000502:physiology*; D011598:Psychoneuroimmunology / Q000379:methods; D013564:Sympathetic Nervous System / Q000502:physiology
D016207:Cytokines