Oxidation of methyl trimethylsilyl ketene acetals to alpha-hydroxyesters with urea hydrogen peroxide catalyzed by methyltrioxorhenium
In the presence of catalytic amounts of MTO, methyltrioxorhenium, methyl trimethylsilyl ketene acetals are oxidized with urea hydrogen peroxide to afford alpha-hydroxy and alpha-siloxy esters. On treatment with potassium fluoride, the alpha-hydroxy esters are obtained in high yields.
Stankovic
S
Ames Laboratory and Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
Espenson
JH