[Left ventricular diastolic function evaluated by Doppler echocardiography in coronary artery disease in relation to to systolic function].
The aim of the study was to assess the relationship between left ventricular (LV) diastolic dysfunction measured by Doppler mitral flow indices (D.m.f.i.) and LV systolic performance in coronary artery disease (CAD). 107 pts with confirmed CAD without or after MI in I, II NYHA class was divided into 2 groups according to ejection fraction (EF) value = 55%. 13 D.m.f.i. regarding to the time, velocity, flow volume and derivates were calculated. In the patient with CAD with normal EF, the diastolic dysfunction was characterised by the impaired relaxation. There were prolonged isovolumic relaxation time IVRT and deceleration time of early filling flow DT, reduced early filling fraction EFF and increased the atrial filling fraction AFF, decreased E/A ratio and E/A-VTI. The regression analysis revealed the positive correlation between EF and DT r = 0.35 and inverse correlation between wall motion score index WMSI and DT r = DT r = -0.33. The stepwise regression analysis revealed that EF and WMSI are independent factors influencing on DT. Our results confirm that diastolic dysfunction precedes the systolic dysfunction in CAD. The correlation between D.m.f.i. and LV systolic function parameters were obtained. The results suggest that the LV systolic function should be take to account in the Doppler mitral flow analysis.
Kowalska
A
A
Oddział Kardiologiczny Dolnoślaskiego, Szpitala Specjalistycznego, T. Marciniaka we Wrocławiu.
Loboz-Grudzień
K
K
Hirnle
T
T
Sokalski
L
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000150:complications*; D015150:Echocardiography, Doppler / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013599:Systole / Q000502:physiology*; D018487:Ventricular Dysfunction, Left / Q000150:complications* / Q000000981:diagnostic imaging*