title: Intracavitary radiotherapy for refractory dysfunctional uterine bleeding. A case report.
abstract: BACKGROUND
  Pelvic irradiation was once a common treatment for dysfunctional uterine bleeding (DUB). Today the majority of women with DUB are successfully treated with hormonal therapy; patients unresponsive to hormonal therapy may require endometrial ablation or hysterectomy. We present a patient with severe, intractable DUB and contraindications to surgery who was treated with intracavitary radiotherapy.
  
  
  METHODS
  A 39-year-old, 150-cm-tall, 310-kg woman was referred for management of severe DUB refractory to medical management. The bleeding was successfully treated with intracavitary cesium. Hysterectomy was not recommended due to the operative risks posed by the patient's massive obesity. Because of technical difficulties during a previous dilation and curettage and the expense of long-term GnRH agonist therapy, the patient elected to undergo intracavitary radiotherapy.
  
  
  CONCLUSIONS
  In selected patients, intracavitary radiotherapy can be used to treat DUB when conventional therapy fails or is contraindicated.
authors.affiliation: Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville 32610-0294, USA.
authors.forename: J
authors.initials: J
authors.lastname: Cassisi
authors.forename: J D
authors.initials: JD
authors.lastname: Davis
authors.forename: B B
authors.initials: BB
authors.lastname: Bennett
authors.forename: F W
authors.initials: FW
authors.lastname: McLean
authors.forename: R B
authors.initials: RB
authors.lastname: Marcus
mesh_terms: D000328:Adult; D001918:Brachytherapy / Q000379:methods*; D002588:Cesium Radioisotopes / Q000627:therapeutic use; D005260:Female; D006801:Humans; D012008:Recurrence; D016896:Treatment Outcome; D014592:Uterine Hemorrhage / Q000532:radiotherapy*
chemical_list: D002588:Cesium Radioisotopes