title: Scintigraphic detection of equine orthopedic infection using Tc-HMPAO labeled leukocytes in 14 horses.
abstract: The aim of this study was to evaluate the diagnostic value of 99mTc-HMPAO leukocyte scintigraphy (LS) by means of a retrospective review of its use in 14 horses that were evaluated for orthopedic infection as a cause of lameness. A total of 17 LS exams were performed in 14 horses. LS studies were positive in 10 of 14 horses. A bacterial infection was confirmed with cytology or culture in 9 of 10 positive horses. Negative LS studies occurred in 4 of 14 horses. Necropsy confirmed the lack of infection in 2 of the 4 horses. Other clinical data and a favorable clinical outcome supported a negative study in the other 2 horses. No false negative or false positive studies were identified. It may be concluded that HMPAO-LS is an effective tool for the diagnosis of orthopedic infection in horses.
authors.affiliation: Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616-8745, USA.
authors.forename: C D
authors.initials: CD
authors.lastname: Long
authors.forename: L D
authors.initials: LD
authors.lastname: Galuppo
authors.forename: N K
authors.initials: NK
authors.lastname: Waters
authors.forename: W J
authors.initials: WJ
authors.lastname: Hornof
mesh_terms: D000818:Animals; D001850:Bone Diseases, Infectious / Q000150:complications / Q000000981:diagnostic imaging / Q000662:veterinary*; D006734:Horse Diseases / Q000000981:diagnostic imaging*; D006736:Horses; D007794:Lameness, Animal / Q000000981:diagnostic imaging / Q000209:etiology*; D007866:Leg / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging / Q000379:methods / Q000662:veterinary; D012189:Retrospective Studies; D019690:Technetium Tc 99m Exametazime
chemical_list: D019690:Technetium Tc 99m Exametazime