title: Evaluation of a Hungarian acaricide original molecule based on its environmental toxicological studies.
abstract: The results of the environmental toxicological investigations and their results of a new hungarian acaricide molecule (SZI-121) developed by the CHINOIN were summarized. The toxicological effects of the test item on different ecotoxicological test systems were investigated in the following tests: Bacterium, alga, and plant growth inhibition tests, acute immobilization and 21 days reproduction tests on Daphnia magna, acute fish test, closed bottle test, mobility, aerob degradation and adsorption/desorption tests on three different soils. No toxic effect was found in the bacterium, alga, plant growth inhibition and acute fish tests in the highest concentrations used. In the Daphnia immobilization test 0.14 mg/l LC50 value was established in the concentration range of 0.0128-40 mg/l applied. The test item showed similar characteristics as the reference item during the mobility test in soils, the adsorption/desorption study and the degradation investigations. In order to determine the environmental degradation rate further degradation investigations, as well as the nitrogen mineralization test and the model of concentration change in natural waters were performed.
authors.affiliation: Toxicological Research Centre Ltd., Veszprém, Szabadságpuszta, Hungary.
authors.forename: D
authors.initials: D
authors.lastname: Szamosi
authors.forename: B
authors.initials: B
authors.lastname: Oláh
authors.forename: G
authors.initials: G
authors.lastname: Hirka
authors.forename: L
authors.initials: L
authors.lastname: Pap
authors.forename: S
authors.initials: S
authors.lastname: Gáty
mesh_terms: D000053:Acari / Q000187:drug effects*; D000818:Animals; D001419:Bacteria / Q000187:drug effects / Q000254:growth & development; D001673:Biodegradation, Environmental; D003621:Daphnia / Q000187:drug effects; D004785:Environmental Pollutants / Q000378:metabolism / Q000633:toxicity*; D005069:Evaluation Studies as Topic; D005399:Fishes; D006571:Heterocyclic Compounds / Q000378:metabolism / Q000633:toxicity*; D006814:Hungary; D007306:Insecticides / Q000378:metabolism / Q000633:toxicity*; D063245:Plant Development; D010944:Plants / Q000187:drug effects
chemical_list: D004785:Environmental Pollutants; D006571:Heterocyclic Compounds; D007306:Insecticides; C417227:flufenzine