[Genetic mapping in relation to disease susceptibility].
The search for chromosome regions that potentially harbour susceptibility genes for diseases by investigating the inheritance of disease and DNA markers in groups of patients is the initial step in the identification of the specific genes involved. The identification of genes involved in disease susceptibility is one of the main research strategies for unravelling the etiology and pathophysiology of many common diseases. However, such diseases often have a complex etiology which makes the genetic mapping of the involved disease genes very difficult. Fortunately, a number of different methods exist for genetic mapping of disease genes.
Ewald
H L
HL
Institut for Psykiatrisk Grundforskning, Psykiatrisk Hospital i Arhus.
Kruse
T A
TA
D002874:Chromosome Mapping; D005819:Genetic Markers; D020022:Genetic Predisposition to Disease; D006801:Humans
D005819:Genetic Markers