title: Crohn's disease incidence in Cardiff from 1930: an update for 1991-1995.
abstract: OBJECTIVE
  To report the incidence of Crohn's disease in the city of Cardiff between 1991 and 1995, in relation to the data of the preceding 65 years.
  
  
  METHODS
  The incidence of Crohn's disease was studied by collecting information from clinical records, the department of pathology database and a questionnaire sent to local family practitioners.
  
  
  RESULTS
  Eighty-four new patients with Crohn's disease, and resident in Cardiff, were diagnosed between 1991 and 1995. The mean incidence for this quinquennium was 56 cases per 10(6) population per year (95% confidence interval, 44-68). There was a female predominance, particularly in young adults, with an overall male to female ratio of 0.47. Colorectal disease was the most common site of disease at the time of diagnosis.
  
  
  CONCLUSIONS
  In relation to the findings of our previous studies, the data suggest that the overall incidence of Crohn's disease is now stable, but that the proportion with colorectal disease continues to increase and there is a marked female preponderance in Crohn's disease presenting in young people.
authors.affiliation: Department of Gastroenterology, University Hospital of Wales, Cardiff, UK.
authors.forename: T R
authors.initials: TR
authors.lastname: Yapp
authors.forename: R
authors.initials: R
authors.lastname: Stenson
authors.forename: G A
authors.initials: GA
authors.lastname: Thomas
authors.forename: B W
authors.initials: BW
authors.lastname: Lawrie
authors.forename: G T
authors.initials: GT
authors.lastname: Williams
authors.forename: A B
authors.initials: AB
authors.lastname: Hawthorne
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D016001:Confidence Intervals; D003424:Crohn Disease / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012042:Registries; D012307:Risk Factors; D017678:Sex Distribution; D011795:Surveys and Questionnaires; D006113:United Kingdom / Q000453:epidemiology