Natural versus drug-induced resistance in Schistosoma mansoni infection.
Rodrigo Corrêa-Oliveira, Iramaya Rodrigues Caldas and Giovanni Gazzinelli here focus on the immune response of individuals with natural resistance to schistosomiasis, which differs significantly from that of post-treatment resistant and infected individuals. They suggest that the activation of T helper type 1 (Th1) and Th2 cells is needed for the induction of natural resistance against Schistosoma mansoni infection.
Corrêa-Oliveira
R
R
Laboratório de Imunologia Celular e Molecular, Centro de Pesquisas René Rachou - FIOCRUZ, Av. Augusto de Lima 1715, Belo Horizonte, MG, 30190-002, Brazil. correa@cpqrr.fiocruz.br
Caldas
I R
IR
Gazzinelli
G
G
D000818:Animals; D000917:Antibody Formation; D007111:Immunity, Cellular; D007113:Immunity, Innate; D012555:Schistosomiasis mansoni / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer