Climbing fiber synapse elimination during postnatal cerebellar development requires signal transduction involving G alpha q and phospholipase C beta 4.
Hashimoto
K
K
Department of Physiology, Kanazawa University School of Medicine, Japan.
Watanabe
M
M
Kurihara
H
H
Offermanns
S
S
Jiang
H
H
Wu
Y
Y
Jun
K
K
Shin
H S
HS
Inoue
Y
Y
Wu
D
D
Simon
M I
MI
Kano
M
M
D000367:Age Factors; D000818:Animals; D001259:Ataxia / Q000235:genetics / Q000503:physiopathology; D048429:Cell Size / Q000235:genetics; D002531:Cerebellum / Q000166:cytology / Q000254:growth & development* / Q000502:physiology; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology; D043802:GTP-Binding Protein alpha Subunits, Gq-G11; D019204:GTP-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D015971:Gene Expression Regulation, Enzymologic; D007527:Isoenzymes / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D008818:Mice, Neurologic Mutants; D008854:Microscopy, Electron; D009412:Nerve Fibers / Q000201:enzymology / Q000648:ultrastructure; D009924:Organ Culture Techniques; D054799:Phospholipase C beta; D011689:Purkinje Cells / Q000201:enzymology / Q000648:ultrastructure*; D012333:RNA, Messenger / Q000032:analysis; D015398:Signal Transduction / Q000502:physiology*; D013569:Synapses / Q000201:enzymology* / Q000648:ultrastructure; D010738:Type C Phospholipases / Q000235:genetics / Q000378:metabolism*
D007527:Isoenzymes; D012333:RNA, Messenger; D010738:Type C Phospholipases; D054799:Phospholipase C beta; C518043:Plcb4 protein, mouse; D019204:GTP-Binding Proteins; D043802:GTP-Binding Protein alpha Subunits, Gq-G11