Antithrombin activity of medicinal plants of the Azores.
A chromogenic bioassay was utilized to determine the antithrombin activity of methylene chloride and methanol extracts prepared from 50 plants of Azores. Extracts of the six plants Hedychium gardneranum, Tropaeolum majus, Gunnera tinctoria, Hedera helix, Festuca jubata and Laurus azorica demonstrated activity of 78% or higher in this bioassay system.
de Medeiros
J M
JM
Instituto de Inovacao Tecnologica Dos Azores, Azores, Portugal.
Macedo
M
M
Contancia
J P
JP
Nguyen
C
C
Cunningham
G
G
Miles
D H
DH
D001394:Azores; D001681:Biological Assay; D002863:Chromogenic Compounds; D004353:Drug Evaluation, Preclinical; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D013917:Thrombin / Q000037:antagonists & inhibitors*
D002863:Chromogenic Compounds; D010936:Plant Extracts; D013917:Thrombin