[Clinical dimensions and visually guided saccades in schizophrenia].
Eye movement anomalies are more frequent in schizophrenic patients than in healthy subjects. This study deals with visually guided saccadic eye movements in seventeen schizophrenic patients [ten untreated (neuroleptic-naive or free), seven treated patients] and their correlations between symptoms presented by patients and oculomotor performances. There was no significant difference between the patients and the control group in visually guided saccades tasks. However, negative correlations between oculomotor performance and positive or disorganisation symptomatology were found. Thus, although no major oculomotor dysfunction in response to external stimulus was seen in schizophrenic patients, some symptoms were linked to oculomotor performance impairment. Thus psychiatric symptoms might share some common cerebral circuits which those involved in oculomotor tasks.
Gut-Fayand
A
A
Laboratoire de Psychiatrie Biologique du Professeur Lôo, Université Paris V, Hôpital Sainte-Anne.
Amado
I
I
Bourdel
M C
MC
Willard
D
D
Lôo
H
H
Olie
J P
JP
Poirier
M F
MF
Krebs
M O
MO
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009802:Oculomotor Nerve / Q000503:physiopathology; D011930:Reaction Time / Q000502:physiology; D012438:Saccades / Q000502:physiology; D012559:Schizophrenia / Q000175:diagnosis* / Q000503:physiopathology; D012565:Schizophrenic Psychology