title: Serum feline trypsin-like immunoreactivity following administration of ceruletide to healthy cats.
abstract: OBJECTIVE
  To determine changes in serum feline trypsin-like immunoreactivity (fTLI) in response to administration of ceruletide to healthy cats.
  
  
  METHODS
  11 healthy cats.
  
  
  METHODS
  Serum fTLI was determined, using a radioimmunoassay, before and 10, 20, 30, 40, and 50 minutes after IM administration of ceruletide (0.3 mg/kg [0.14 mg/lb]).
  
  
  RESULTS
  Mean +/- SD baseline serum fTLI was 23.1 +/- 4.1 mg/L. There was a statistically significant, but clinically unimportant, increase in serum fTLI 10 and 30 minutes after ceruletide administration.
  
  
  CONCLUSIONS
  In healthy cats, administration of ceruletide induced a statistically significant, but clinically unimportant, increase in serum fTLI. Whether responses in cats with exocrine pancreatic disorders would be different is unknown, but results suggest that a ceruletide stimulation test would likely not be useful for differentiating between healthy cats and cats with subclinical chronic exocrine pancreatic disorders.
authors.affiliation: Medizinische und Gerichtliche Veterinärklinik I der Justus-Liebig-Universität Giessen, Innere Krankheiten der Kleintiere, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Spillmann
authors.forename: I
authors.initials: I
authors.lastname: Jacob
authors.forename: J M
authors.initials: JM
authors.lastname: Steiner
authors.forename: D A
authors.initials: DA
authors.lastname: Williams
authors.forename: K
authors.initials: K
authors.lastname: Failing
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis*; D002415:Cats; D002108:Ceruletide / Q000494:pharmacology*; D010182:Pancreatic Diseases / Q000175:diagnosis / Q000662:veterinary*; D011863:Radioimmunoassay / Q000662:veterinary; D014357:Trypsin / Q000097:blood*
chemical_list: D002108:Ceruletide; D014357:Trypsin