title: Imaging in isolated sacral tuberculosis: a review of 15 cases.
abstract: OBJECTIVE
  To review imaging studies of isolated involvement of the sacrum due to tuberculosis and determine the role of imaging in the diagnosis and management of these patients.
  
  
  METHODS
  A retrospective analysis of 15 cases of isolated sacral tuberculosis imaged with MR imaging was performed. The CT images were also reviewed where available, and the various lesion characteristics were identified. We also reviewed the medical records in an attempt to determine the impact of the imaging studies on the management of these patients.
  
  
  RESULTS
  Fifteen patients (5 male, 10 female) presented with symptoms of 3-15 months' duration. Chronic localized backache with muscle spasm was the commonest presenting symptom; discharging sinuses with abscess formation was found in six patients, five of whom were children. MR imaging of the sacrum revealed a hypointense marrow signal on T1-weighted images and hyperintense signal on T2-weighted images in 14 of 15 patients, the S2 vertebra being always involved. CT revealed osteolytic changes in the sacrum in all the five patients in whom CT was performed. All patients showed marked clinical improvement within 1 year of anti-tuberculous chemotherapy.
  
  
  CONCLUSIONS
  Isolated tuberculosis of the sacrum is uncommon but should be suspected in patients presenting with chronic low backache or children with discharging sinuses/abscesses and showing sacral destruction on CT or MR imaging. MR imaging can identify cases and enables early institution of antituberculous chemotherapy.
authors.affiliation: Department of Radiology, King Edward Memorial Hospital, Bombay, India.
authors.forename: T
authors.initials: T
authors.lastname: Patankar
authors.forename: A
authors.initials: A
authors.lastname: Krishnan
authors.forename: D
authors.initials: D
authors.lastname: Patkar
authors.forename: H
authors.initials: H
authors.lastname: Kale
authors.forename: S
authors.initials: S
authors.lastname: Prasad
authors.forename: J
authors.initials: J
authors.lastname: Shah
authors.forename: M
authors.initials: M
authors.lastname: Castillo
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003287:Contrast Media; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012447:Sacrum / Q000000981:diagnostic imaging* / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014399:Tuberculosis, Spinal / Q000175:diagnosis*
chemical_list: D003287:Contrast Media