title: Calciphylaxis in moderate renal insufficiency: changing disease concepts.
abstract: Calciphylaxis is a rare but frequently fatal complication in patients with end-stage renal disease. Original concepts regarding groups at risk for the disease, predisposing factors, and associated morbidity have changed significantly in the past few years as more cases are reported. We present a patient who developed fatal calciphylaxis in the setting of moderate renal insufficiency to illustrate some of the evolving concepts in this disease process.
authors.affiliation: Department of Internal Medicine, Naval Medical Center San Diego, CA 92134-1005, USA. wimacallister@nmcsd.med.navy.mil
authors.forename: C M
authors.initials: CM
authors.lastname: Smiley
authors.forename: S U
authors.initials: SU
authors.lastname: Hanlon
authors.forename: D M
authors.initials: DM
authors.lastname: Michel
mesh_terms: D000368:Aged; D002115:Calciphylaxis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D007871:Leg Ulcer / Q000209:etiology