title: Enzymatic acylation and ring-closing olefin metathesis: a convenient strategy for the lactone moiety of compactin and mevinolin.
authors.affiliation: Department of Chemistry, University of Illinois at Chicago, 60607, USA. arunghos@uic.edu
authors.forename: A K
authors.initials: AK
authors.lastname: Ghosh
authors.forename: H
authors.initials: H
authors.lastname: Lei
mesh_terms: D000215:Acylation; D000475:Alkenes / Q000737:chemistry / Q000378:metabolism; D002384:Catalysis; D004800:Enzymes, Immobilized / Q000378:metabolism; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000737:chemistry* / Q000378:metabolism*; D007783:Lactones / Q000737:chemistry* / Q000378:metabolism*; D008049:Lipase / Q000378:metabolism*; D008148:Lovastatin / Q000031:analogs & derivatives / Q000737:chemistry* / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D004800:Enzymes, Immobilized; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007783:Lactones; C012258:mevastatin; D008148:Lovastatin; D008049:Lipase