title: [Failure of bone marrow autograft in metastatic malignant adrenalcortical carcinoma].
abstract: BACKGROUND
  Despite different therapeutic modalities (surgery, hormones therapy, chemotherapy), 5-year survival in patients with malignant adrenocortical carcinoma remains only 10% to 20%. Bone marrow grafts may be proposed to intensify treatment.
  
  
  METHODS
  In a 29-year-old patient with adrenocortical carcinoma with metastases to the lung and bone, an adjuvant bone marrow graft using peripheral stem cells was unsuccessful. Recurrence was observed at 3 months and overall survival was 2 years.
  
  
  CONCLUSIONS
  Our case illustrates the feasibility of this approach but also emphasizes the relatively poor results obtains with only 2 years survival (1 year after the bone marrow graft), comparable with other classical modalities reported in the literature.
authors.affiliation: Service de Médecine Interne et Nutrition, Hôpital de Hautepierre, Strasbourg. medecineinterne.chuhautepierre@wanadoo.fr
authors.forename: E
authors.initials: E
authors.lastname: Andrès
authors.forename: J E
authors.initials: JE
authors.lastname: Kurtz
authors.forename: B
authors.initials: B
authors.lastname: Lioure
authors.forename: P
authors.initials: P
authors.lastname: Quetin
authors.forename: F
authors.initials: F
authors.lastname: Maloisel
authors.forename: J L
authors.initials: JL
authors.lastname: Schlienger
authors.forename: P
authors.initials: P
authors.lastname: Dufour
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D000328:Adult; D001859:Bone Neoplasms / Q000556:secondary; D002277:Carcinoma / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D017809:Fatal Outcome; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D009362:Neoplasm Metastasis; D014182:Transplantation, Autologous; D017211:Treatment Failure