Immunological hiding of herpesvirus-infected cells.
Over the past years, numerous research groups have discovered various strategies that herpesviruses use to hide themselves from recognition by the immune system of their hosts. The current review gives a summary of this research, with emphasis on the mechanisms by which herpesvirus-infected cells escape from elimination by complement, phagocytes, cytotoxic T-lymphocytes and/or natural killer cells.
Favoreel
H W
HW
Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Belgium.
Nauwynck
H J
HJ
Pensaert
M B
MB
D000818:Animals; D016525:Antigenic Modulation; D003602:Cytotoxicity, Immunologic; D006561:Herpes Simplex / Q000276:immunology* / Q000821:virology; D010587:Phagocytosis / Q000276:immunology; D051381:Rats; D018139:Simplexvirus / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology