Glucose: a reevaluation of its intraoperative use in paediatric surgery.
Blood glucose concentration was measured in 100 children immediately before and during surgery. These children were randomly assigned to receive either lactated Ringer's (LR) solution or 5% dextrose in lactated Ringer's (5%D/LR) intraoperatively as maintenance and replacement fluids. Blood samples were taken immediately after induction of anaesthesia and at 1/2, 1, 1.5, 2 and subsequent hours. Blood glucose concentration was assayed by a reflectance meter. None of the patients was noted to be hypoglycaemic pre- and intraoperatively. Intraoperative blood glucose concentration increased significantly (p < 0.05) from preoperative levels for both groups of children but the increase in those that received 5%D/LR was significantly greater (p < 0.05) than those who received LR. The number of children who were hyperglycaemic during surgery was also greater in those who received 5% dextrose in lactated Ringer's as their intraoperative fluid. These data suggest that lactated Ringer's alone is a safe and appropriate fluid for intraoperative fluid therapy in children.
Lim
S K
SK
Department of Anaesthesiology and Intensive Care, Universiti Kebangsaan Malaysia, Kuala Lumpur.
Loh
S P
SP
D000367:Age Factors; D001786:Blood Glucose / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D005440:Fluid Therapy; D006801:Humans; D007223:Infant; D007552:Isotonic Solutions / Q000494:pharmacology; D016343:Monitoring, Intraoperative; D000077325:Ringer's Lactate
D001786:Blood Glucose; D007552:Isotonic Solutions; D000077325:Ringer's Lactate