title: Hepatic malignancies: improved detection with pulse-inversion US in late phase of enhancement with SH U 508A-early experience.
abstract: Twenty consecutive patients with known liver malignancies underwent ultrasonography (US) in conventional B mode and in pulse-inversion mode in the late hepatic-specific parenchymal phase after intravenous administration of SH U 508A, a microbubble US contrast agent. Two experienced readers assessed subjective and objective conspicuity, number of lesions, and smallest lesion diameter in each mode. Subjective and objective conspicuity were improved with pulse-inversion mode, and smaller lesions were depicted with pulse-inversion mode than with conventional B mode, improving the detection of metastases less than 1 cm in size.
authors.affiliation: Department of Imaging, Hammersmith Hospital, London, England.
authors.forename: C J
authors.initials: CJ
authors.lastname: Harvey
authors.forename: M J
authors.initials: MJ
authors.lastname: Blomley
authors.forename: R J
authors.initials: RJ
authors.lastname: Eckersley
authors.forename: D O
authors.initials: DO
authors.lastname: Cosgrove
authors.forename: N
authors.initials: N
authors.lastname: Patel
authors.forename: R A
authors.initials: RA
authors.lastname: Heckemann
authors.forename: J
authors.initials: J
authors.lastname: Butler-Barnes
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging*; D003287:Contrast Media; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D011134:Polysaccharides; D012016:Reference Values; D012680:Sensitivity and Specificity; D014463:Ultrasonography
chemical_list: D003287:Contrast Media; D011134:Polysaccharides; C059891:SHU 508