New advances in pharmacogenomics.
In the years to come, pharmacogenomics will make an impact on the development of new drugs. Numerous publications have shown that gene polymorphism can influence drug toxicity and/or efficacy. In order to improve current applications of pharmacogenomics, some technical limitations regarding marker generation, genotyping and biostatistical analysis are being overcome.
Destenaves
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B
GENSET SA, Genomic Research Centre, Department of Pharmacogenomics and Medical Affairs, Evry, France.
Thomas
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F
D015195:Drug Design; D004341:Drug Evaluation; D064420:Drug-Related Side Effects and Adverse Reactions / Q000235:genetics; D014644:Genetic Variation; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D020411:Oligonucleotide Array Sequence Analysis; D010597:Pharmacogenetics; D011110:Polymorphism, Genetic; D020641:Polymorphism, Single Nucleotide / Q000235:genetics