title: A pilot study to measure cognitive efficiency during migraine.
abstract: OBJECTIVE
  The measurement of cognitive efficiency during migraine has produced conflicting results primarily due to the types of tests used. The objectives of this pilot study were two-fold: to measure cognitive efficiency during migraine, compared to a migraine-free period, and to evaluate the effects of therapy with a 5-HT1 agonist (sumatriptan injection, 6 mg) on the cognitive efficiency of migraineurs during a migraine.
  
  
  METHODS
  The Headache Care Center-Automated Neuropsychological Assessment Metrics was administered to 10 migraineurs, three times without a migraine, once during a migraine, and three times after administration of sumatriptan injection (6 mg).
  
  
  RESULTS
  The results demonstrated a significant drop in cognitive efficiency during migraine and recovery 15 minutes after therapeutic injection.
  
  
  CONCLUSIONS
  This pilot study is the first to document a significant drop in cognitive functioning during migraine and recovery after administration of a migraine-specific medication.
authors.affiliation: Headache Care Center, Springfield, MO 65804, USA.
authors.forename: K
authors.initials: K
authors.lastname: Farmer
authors.forename: R
authors.initials: R
authors.lastname: Cady
authors.forename: J
authors.initials: J
authors.lastname: Bleiberg
authors.forename: D
authors.initials: D
authors.lastname: Reeves
mesh_terms: D003071:Cognition / Q000187:drug effects; D008881:Migraine Disorders / Q000188:drug therapy / Q000523:psychology*; D009483:Neuropsychological Tests; D010865:Pilot Projects; D012016:Reference Values; D017366:Serotonin Receptor Agonists / Q000627:therapeutic use; D018170:Sumatriptan / Q000627:therapeutic use
chemical_list: D017366:Serotonin Receptor Agonists; D018170:Sumatriptan