Evaluation of the in vitro antioxidant activity of Mangifera indica L. extract (Vimang).
An extract of Mangifera indica L. (Vimang) was tested in vitro for its antioxidant activity using commonly accepted assays. It showed a powerful scavenger activity of hydroxyl radicals and hypochlorous acid and acted as an iron chelator. The extract also showed a significant inhibitory effect on the peroxidation of rat-brain phospholipid and inhibited DNA damage by bleomycin or copper-phenanthroline systems.
Martínez
G
G
Center for Evaluation and Biological Research, Institute of Pharmacy, Havana University, Cuba. gregorio@cieb.sld.cu
Delgado
R
R
Pérez
G
G
Garrido
G
G
Núñez Sellés
A J
AJ
León
O S
OS
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D004249:DNA Damage / Q000187:drug effects; D005638:Fruit; D015227:Lipid Peroxidation / Q000187:drug effects*; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology; D018547:Plant Stems; D051381:Rats; D019685:Rosales
D000975:Antioxidants; D010936:Plant Extracts