AIDS-related primary CNS lymphoma: a brief review.
Primary CNS lymphoma, which has a strong association with Epstein-Barr virus, was increasing in incidence in patients with AIDS before the introduction and widespread use of combination antiretroviral therapy. The diagnostic strategies for primary CNS lymphoma, including contrast-enhanced CT or MRI and brain biopsy, are well established. The use of a combination of diagnostic tools to reduce the need for brain biopsy is currently being evaluated. The clinical outcome with current treatments for primary CNS lymphoma in HIV-infected persons remains relatively discouraging.
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Adult Medicine Department at the Lincoln Health Center, Durham, NC, USA.
D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D018791:CD4 Lymphocyte Count; D004279:DNA, Viral / Q000134:cerebrospinal fluid; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
D004279:DNA, Viral