Mathematical modeling of mortality dynamics of mammalian populations exposed to radiation.
A mathematical model is developed which describes the dynamics of radiation-induced mortality of a non-homogeneous (in radiosensitivity) mammalian population. It relates statistical biometric functions with statistical and dynamic characteristics of a critical system in organism of specimens composing this population. The model involves two types of distributions, the normal and the log-normal, of population specimens with respect to the radiosensitivity of the critical system cells. This approach suggests a new pathway in developing the methods of radiation risk assessment.
Smirnova
O A
OA
Research Center of Spacecraft Radiation Safety, Shchukinskaya Str. 40, 123182, Moscow, Russian Federation.
D000818:Animals; D006412:Hematopoietic Stem Cells / Q000528:radiation effects; D006801:Humans; D008433:Mathematics; D051379:Mice; D008954:Models, Biological; D011832:Radiation Injuries / Q000401:mortality*; D011836:Radiation Tolerance; D011853:Radiobiology; D018570:Risk Assessment