title: The validity of telepathological frozen section diagnosis with ISDN-mediated remote microscopy.
abstract: We investigated 109 randomly selected frozen section specimens from lung surgery patients in a retrospective blind mode using telepathology equipment. The telepathology system applied (HISTKOM) used one ISDN B-channel and telemicroscopy with a remotely operated robotic microscope. The performance of telepathological frozen section diagnosis was compared with that of conventional frozen section diagnosis. The false-positive rate achieved was identical for both methods. The sensitivity (P=0.03), but not the specificity, was significantly lower for the telepathological method. The time needed to establish a diagnosis with the remote microscope was too high; therefore, upgrading to multichannel technology is recommended. The quality of the images transmitted was judged to be sufficient by the pathologists involved in the study. In conclusion, with further technical improvements in telemicroscopy and additional experience in telepathology, remote diagnosis seems to be feasible.
authors.affiliation: Robert Bosch Hospital, Department of Pathology, Stuttgart, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Wellnitz
authors.forename: P
authors.initials: P
authors.lastname: Fritz
authors.forename: V
authors.initials: V
authors.lastname: Voudouri
authors.forename: A
authors.initials: A
authors.lastname: Linder
authors.forename: H
authors.initials: H
authors.lastname: Toomes
authors.forename: J
authors.initials: J
authors.lastname: Schmid
authors.forename: B
authors.initials: B
authors.lastname: Binder
authors.forename: P
authors.initials: P
authors.lastname: Schwarzmann
mesh_terms: D000328:Adult; D001706:Biopsy; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D005629:Frozen Sections; D006801:Humans; D008168:Lung / Q000473:pathology / Q000601:surgery; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008482:Mediastinum / Q000473:pathology; D008853:Microscopy; D008875:Middle Aged; D011786:Quality Control; D012189:Retrospective Studies; D012371:Robotics; D019113:Telepathology; D013997:Time Factors