title: Prurigo nodularis of Hyde: an update.
abstract: Prurigo nodularis of Hyde is an unusual disorder of unknown aetiology characterized by extremely pruritic nodules with well defined clinical and histopathological aspects. The literature on this disease is reviewed, focusing on the historical background, aetiology, pathogenesis, histopathology and ultrastructure, clinical aspects, differential diagnosis and therapeutic alternatives.
authors.affiliation: Sector of Dermatology, School of Medicine, HUCFF-UFRJ, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: L W
authors.initials: LW
authors.lastname: Accioly-Filho
authors.forename: A
authors.initials: A
authors.lastname: Nogueira
authors.forename: M
authors.initials: M
authors.lastname: Ramos-e-Silva
mesh_terms: D002908:Chronic Disease; D003937:Diagnosis, Differential; D006801:Humans; D011536:Prurigo / Q000175:diagnosis / Q000473:pathology / Q000628:therapy