[Outbreak of hemorrhagic fever with kidney syndrome in Egor'ev district of Moscow region].
Epizootological, serological, and molecular virological analysis of an outbreak of hemorrhagic fever with renal syndrome (HFRS) in the Egoryevsk district of Moscow region (September 1995-January 1996) has been carried out. Hantavirus (Puumala) antigen and virus-specific antibodies were isolated from bank voles captured in the endemic focus. Anti-Puumala antibodies were detected in the sera of all HFRS patients and in 2% healthy residents of the endemic focus. Analysis of nucleotide sequence (RNA from hantavirus-positive lung of a bank vole) showed that the studied hantavirus is a distinct genotype of Puumala virus. Hence, a new highly active natural focus of HFRS associated with Puumala virus, dangerous for the population, has been revealed in Moscow region.
Ivanov
A P
AP
Dekonenko
A E
AE
Dzagurova
T K
TK
Malkin
A E
AE
Shervarli
V I
VI
Baranovskiĭ
P M
PM
Vardanian
N V
NV
Bulanov
V E
VE
Nikolaeva
E I
EI
Tkachenko
E A
EA
D000818:Animals; D004196:Disease Outbreaks; D004197:Disease Reservoirs; D018063:Hantaan virus; D006480:Hemorrhagic Fever with Renal Syndrome / Q000453:epidemiology*; D006801:Humans; D009031:Moscow / Q000453:epidemiology