Electrophilic activation of hydrogen peroxide: selective oxidation reactions in perfluorinated alcohol solvents.
[reaction; see text] The catalytic electrophilic activation of hydrogen peroxide with transition metal compounds toward reaction with nucleophiles is a matter of very significant research and practical interest. We have now found that use of perfluorinated alcoholic solvents such as 1,1, 1,3,3,3-hexafluoro-2-propanol in the absence of catalysts allowed electrophilic activation of hydrogen peroxide toward epoxidation of alkenes and the Baeyer-Villiger oxidation of ketones.
Neimann
K
K
Department of Organic Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel.
Neumann
R
R