YC-1, an activation inductor of soluble guanylyl cyclase.
The crystal structure of 1-benzyl-3-(5-hydroxymethyl-2-furyl)indazole, C(19)H(16)N(2)O(2), showed that the furan O and indazole N atoms lie on the same face of the molecule. The crystal packing consists of intermolecular hydrogen bonding, and indazole-indazole and indazole-phenyl interactions.
Sopková-De Oliveira Santos
J
J
Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), Université de Caen, 1 Rue Vaubénard, 14032 Caen, France. sopkova@pharmacie.unicaen.fr
Collot
V
V
Bureau
I
I
Rault
S
S
D018360:Crystallography, X-Ray; D020536:Enzyme Activators / Q000737:chemistry*; D006162:Guanylate Cyclase / Q000096:biosynthesis*; D006860:Hydrogen Bonding; D007191:Indazoles / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation
D020536:Enzyme Activators; D007191:Indazoles; C090937:3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole; D006162:Guanylate Cyclase