title: Solid-phase synthesis of a modified 13-residue seminalplasmin fragment on 1,6-hexanediol diacrylate-crosslinked polystyrene support.
abstract: A novel 1,6-hexanediol diacrylate cross-linked resin was prepared that was subsequently functionalized by using chloromethyl methyl ether to afford a high-capacity resin. The resin exhibited good swelling and its application in the successful synthesis of a 13-residue peptide corresponding to the fragment of seminalplasmin has been illustrated. The resin was chemically inert at peptide synthetic conditions.
authors.affiliation: School of Chemical Sciences, Mahatma Gandhi University, Kottayam, 686560, Kerala, India. mgu@md2.vsnl.net.in
authors.forename: C
authors.initials: C
authors.lastname: Arunan
authors.forename: R
authors.initials: R
authors.lastname: Nagaraj
authors.forename: V N
authors.initials: VN
authors.lastname: Rajasekharan Pillai
mesh_terms: D000179:Acrylates; D006018:Glycols; D010455:Peptides / Q000138:chemical synthesis*; D011137:Polystyrenes; D011506:Proteins / Q000138:chemical synthesis*; D029607:Seminal Vesicle Secretory Proteins
chemical_list: D000179:Acrylates; D006018:Glycols; C095039:Merrifield resin; D010455:Peptides; D011137:Polystyrenes; D011506:Proteins; D029607:Seminal Vesicle Secretory Proteins; C020355:1,6-hexanediol diacrylate; C027765:hexamethylene glycol