(4S,5S)-(+)-4-Hydroxymethyl-2,5-diphenyloxazoline
The absolute configuration of the title compound, alternatively called (+)-(4,5-dihydro-2,5-diphenyloxazol-4-yl)methanol, C(16)H(15)NO(2), has been confirmed as 4S,5S. The hydroxymethyl group and phenyl ring at the asymmetric C atoms exhibit beta and alpha orientations, respectively. The exocyclic C-C bonds at the asymmetric C atoms are mutually anticlinal (-ac). The hydroxyl group and the N atom of the oxazoline ring are involved in an intermolecular hydrogen bond leading to chains of molecules.
Gzella
A
Department of Organic Chemistry, K. Marcinkowski University of Medical Sciences Poznan, ul. Grunwaldzka 6, 60-780 Poznan, Poland. akgzella@eucalyptus.usoms.poznan.pl.
Rozwadowska
MD