Inhaled corticosteroid-induced bone loss and preventive strategies.
Systemic corticosteroids are known to cause adverse effects on bone loss and, with long-term use, may result in osteoporosis. There is evidence that inhaled corticosteroids at moderate to high doses may also induce bone loss. This article discusses the effects of inhaled corticosteroids on bone formation and resorption. It also offers preventive strategies to minimize bone loss associated with long-term use of inhaled corticosteroids.
Singh
R F
RF
Department of Pharmacy Practice, College of Pharmacy and Allied Health, Wayne State University, Detroit, Mich. 48201, USA. rfsingh@med.wayne.edu
Muskelly
C C
CC
D000280:Administration, Inhalation; D000328:Adult; D015519:Bone Density / Q000187:drug effects; D001846:Bone Development / Q000187:drug effects*; D001862:Bone Resorption / Q000139:chemically induced*; D002648:Child; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans
D005938:Glucocorticoids