title: Parasite proteomics.
abstract: Proteomics offers a new set of tools for investigating parasites and parasite-associated disease. In this article, John Barrett, Jim Jefferies and Peter Brophy describe the key technologies involved, including two-dimensional gel electrophoresis, image analysis, biological mass spectroscopy and database searching. The potential applications of proteomics in drug and vaccine discovery are reviewed, as are possible future developments.
authors.affiliation: Institute of Biological Sciences, University of Wales, Aberystwyth, UK SY23 3DA. jzb@aber.ac.uk
authors.forename: J
authors.initials: J
authors.lastname: Barrett
authors.forename: J R
authors.initials: JR
authors.lastname: Jefferies
authors.forename: P M
authors.initials: PM
authors.lastname: Brophy
mesh_terms: D015180:Electrophoresis, Gel, Two-Dimensional; D016678:Genome; D007091:Image Processing, Computer-Assisted; D013058:Mass Spectrometry; D010274:Parasitology / Q000379:methods*; D011506:Proteins / Q000032:analysis; D020543:Proteome
chemical_list: D011506:Proteins; D020543:Proteome