title: Evaluation of named binders in Rauwolfia vomitoria root tablets.
abstract: Some physical properties of Rauwolfia vomitoria root tablets were studied. Tablet characteristics studied were: weight uniformity, tensile strength, friability, disintegration time and content uniformity. Tablet property varied depending on the type and concentration of the binder. The tablets had type and concentration of the binder. The tablets had acceptable hardness and friability profiles. Although tablets containing 150 mg R. vomitoria root had lower tensile strength values. All the tablets passed the B.P. disintegration time test of 15 min. Moreover tablets containing 150 mg R. vomitoria root disintegrated under 1 min. at 4% w/w binder concentration.
authors.affiliation: Department of Pharmaceutical Technology and Industrial Pharmacy-Faculty of Pharmaceutical Sciences-University of Nigeria, Nsukka, Nigeria.
authors.forename: G C
authors.initials: GC
authors.lastname: Onunkwo
mesh_terms: D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000737:chemistry*; D002626:Chemistry, Pharmaceutical; D005079:Excipients; D006245:Hardness Tests; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal; D011926:Rauwolfia / Q000737:chemistry*; D046948:Secologanin Tryptamine Alkaloids / Q000008:administration & dosage / Q000737:chemistry*; D012995:Solubility; D013607:Tablets; D013718:Tensile Strength
chemical_list: D014150:Antipsychotic Agents; D005079:Excipients; D046948:Secologanin Tryptamine Alkaloids; D013607:Tablets