Transient reactive papulotranslucent acrokeratoderma associated with cystic fibrosis.
A 20-year-old female with cystic fibrosis presented with a white marginal palmar eruption after exposure to water. There was no family history of keratoderma. A biopsy showed hyperkeratosis around dilated eccrine ostia. These features are similar to a recently described condition, transient reactive papulotranslucent acrokeratoderma. This is thought to be a variant of hereditary papulotranslucent acrokeratoderma, one of the punctate keratodermas. Association with cystic fibrosis has not been described previously.
Lowes
M A
MA
Dermatology Department, Royal Newcastle Hospital, Australia. malowes@enternet.com.au
Khaira
G S
GS
Holt
D
D
D000328:Adult; D003550:Cystic Fibrosis / Q000150:complications* / Q000473:pathology; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D006945:Hyperhidrosis / Q000150:complications; D007645:Keratoderma, Palmoplantar / Q000209:etiology* / Q000235:genetics / Q000473:pathology / Q000503:physiopathology; D012867:Skin / Q000473:pathology*; D013577:Syndrome; D014867:Water / Q000009:adverse effects*
D014867:Water