title: Nasal pH and saccharin clearance are unrelated in the physiologically normal nose.
abstract: A group of 56 asymptomatic non-smoking men was prospectively recruited to study the relationship between nasal mucosal pH and saccharin clearance rate. No significant relationship was found between the two variables (Pearson correlation coefficient = -.105, p = 0.44). This finding suggests that in vivo mucociliary flow rates are resistant to change within the pH range of the physiologically normal nose.
authors.affiliation: Department of Otolaryngology, Head & Neck Surgery, Bradford Royal Infirmary, W. Yorkshire, United Kingdom.
authors.forename: R J
authors.initials: RJ
authors.lastname: England
authors.forename: R
authors.initials: R
authors.lastname: Anthony
authors.forename: J J
authors.initials: JJ
authors.lastname: Homer
authors.forename: D P
authors.initials: DP
authors.lastname: Martin-Hirsch
mesh_terms: D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D009079:Mucociliary Clearance; D009297:Nasal Mucosa / Q000378:metabolism / Q000502:physiology*; D012220:Rhinitis / Q000503:physiopathology; D012439:Saccharin / Q000378:metabolism*
chemical_list: D012439:Saccharin