Hypothyroidism and primary open-angle glaucoma.
OBJECTIVE
To test if there is an association between hypothyroidism and primary open-angle glaucoma (POAG) and the utility of routine study of thyroid function in these patients.


METHODS
The study was conducted in a case-control fashion. Seventy-five consecutive patients with a previous diagnosis of POAG and 75 control patients were prospectively evaluated for hypothyroidism. The levels of thyroid-stimulating hormone and free thyroxin were measured.


RESULTS
Hypothyroidism was revealed in only 2 patients with previous diagnosis of POAG (2.67%) and 3 patients of the control group (4%).


CONCLUSIONS
As we have not been able to demonstrate the previously reported relationship between hypothyroidism and POAG, we cannot recommend the systematic screening for hypothyroidism in patients with POAG.
Muñoz-Negrete
F J
FJ
Department of Ophthalmology, Ramón y Cajal Hospital, Madrid, Spain. FJMUNOZ@santandersupernet.com
Rebolleda
G
G
Almodóvar
F
F
Díaz
B
B
Varela
C
C
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D005902:Glaucoma, Open-Angle / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D013030:Spain / Q000453:epidemiology; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
D015415:Biomarkers; D013972:Thyrotropin; D013974:Thyroxine