Comparative In vitro activities of ertapenem (MK-0826) against 1,001 anaerobes isolated from human intra-abdominal infections.
By using an agar dilution method, the comparative in vitro activities of ertapenem (MK-0826) were studied against 1,001 anaerobes isolated from human intra-abdominal infections in 17 countries worldwide. MK-0826 was uniformly active against all isolates, including all Bacteroides fragilis group species isolates, with the exception of 12 of 61 (20%) strains of Bilophila wadsworthia, 3 strains of lactobacilli, and 1 isolate of Acidaminococcus fermentans. Geographical variation in activity was not observed.
Goldstein
E J
EJ
R. M. Alden Research Laboratory, Santa Monica-University of California at Los Angeles Medical Center, 90404, USA. EJCGMD@aol.com
Citron
D M
DM
Vreni Merriam
C
C
Warren
Y
Y
Tyrrell
K L
KL
D018784:Abdominal Abscess / Q000382:microbiology*; D001421:Bacteria, Anaerobic / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D001938:Brazil; D015780:Carbapenems / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D012426:Russia; D013019:South Africa; D013030:Spain
D015780:Carbapenems; C108047:L 749345