title: [Anesthesiologic management in the treatment of patients with cystic fibrosis].
abstract: OBJECTIVE
  Improvements in the management of patients with cystic fibrosis (CF) result in increased life expectancy. Thus it is likely that anesthetists will see this patients with increasing frequency. This study describes our experiences in the anesthetic management of CF patients.
  
  
  METHODS
  We descriptively and retrospectively reviewed the records of all CF patients from 1981 until 1997 who underwent elective surgery in our department of ear, nose and throat and in whom general anesthesia was required.
  
  
  RESULTS
  199 anesthetics in 53 patients were reviewed. Premedication with midazolam (0.4 +/- 0.07 mg/kg) were given orally in 163 of the 199 anesthetics (82%). In 45 anesthetics the induction was performed by Inhalation with halothane (23%). Atropine (0.21 +/- 0.11 mg/kg) was used in 69 cases for induction. 57 pulmonary function tests were performed preoperatively mostly showing no severe abnormalities. We documented 10 perioperative respiratory complications (5%) in 199 procedures. No patient died at hospital.
  
  
  CONCLUSIONS
  In patients with cystic fibrosis undergoing minor ear, nose and throat surgery who do not show significant reduction in pulmonary function anesthesia can be safely carried out.
authors.affiliation: Klinik für Anästhesiologie und Operative Intensivmedizin, Klinikum der Stadt Ludwigshafen, Akademisches Lehrkrankenhaus Johannes-Gutenberg-Universität Mainz.
authors.forename: B
authors.initials: B
authors.lastname: Kumle
authors.forename: R
authors.initials: R
authors.lastname: Breug
authors.forename: J
authors.initials: J
authors.lastname: Boldt
authors.forename: G
authors.initials: G
authors.lastname: Münker
mesh_terms: D000328:Adult; D000758:Anesthesia / Q000009:adverse effects; D003550:Cystic Fibrosis / Q000150:complications*; D004423:Ear / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D013508:Ophthalmologic Surgical Procedures; D010614:Pharynx / Q000601:surgery; D011229:Preanesthetic Medication; D012129:Respiratory Function Tests; D012189:Retrospective Studies; D013514:Surgical Procedures, Operative