Substance P.
Substance P is considered to be an important neuropeptide in nociceptive processes. Although substance P was described more than 60 years ago, there is still controversy about its exact role in nociception. This article reviews the current knowledge about the function of substance P in pain. Special emphasis is put on how to use this knowledge in the development of new ways to treat pain.
Snijdelaar
D G
DG
Department of Anesthesiology/Pain Center, University Hospital, Nijmegen, The Netherlands. dik.snijdelaar@usa.net
Dirksen
R
R
Slappendel
R
R
Crul
B J
BJ
D002490:Central Nervous System / Q000737:chemistry / Q000502:physiology; D006801:Humans; D010146:Pain / Q000503:physiopathology*; D013373:Substance P / Q000502:physiology*
D013373:Substance P