[Mesalamine-induced hypersensitivity pneumonitis].
A 23-year-old woman was admitted with a history of 2 weeks of cough, fever and bilateral lung infiltrates. She had been diagnosed 2 months before as having ulcerative proctitis and was treated with mesalamine, which induced a full remission, but 3 antibiotic regimens failed to improve her lung disease. Since computerized tomography revealed bilateral peripheral lung infiltrates and her eosinophile count was elevated, the diagnosis of drug-induced eosinophilic pneumonia was suggested. Mesalamine and antibiotics were stopped and oral corticosteroids begun. She became almost asymptomatic a week after mesalamine withdrawal, and the x-ray became normal.
Zamir
D
D
Dept. of Medicine A, Hillel Yaffe Medical Center, Hadera.
Weizman
J
J
Zamir
C
C
Fireman
Z
Z
Weiner
P
P
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003093:Colitis, Ulcerative / Q000188:drug therapy; D004342:Drug Hypersensitivity / Q000188:drug therapy; D005260:Female; D006801:Humans; D019804:Mesalamine / Q000009:adverse effects*; D011014:Pneumonia / Q000139:chemically induced* / Q000188:drug therapy; D011349:Proctitis / Q000188:drug therapy
D000305:Adrenal Cortex Hormones; D000894:Anti-Inflammatory Agents, Non-Steroidal; D019804:Mesalamine