Separation of gallic acid from Cornus officinalis Sieb. et Zucc by high-speed counter-current chromatography.
Gallic acid was separated from a n-butanol extract of the fruit of Cornus officinalis Sieb. et Zucc by high-speed countercurrent chromatography in two steps using two solvent systems composed of ethyl-acetate-ethanol n-butanol-water (5:1.8:6, v/v/v) and ethyl acetate-ethanol-water (5:0.5:6, v/v/v) successively. From 1 g of n-butanol extract the method produced 60 mg of gallic acid at a purity of 97%.
Tian
G
G
Beijing Institute of New Technology Application, China.
Zhang
T
T
Yang
F
F
Ito
Y
Y
D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005707:Gallic Acid / Q000302:isolation & purification*; D008516:Medicine, Chinese Traditional; D010946:Plants, Medicinal / Q000737:chemistry*
D005707:Gallic Acid