title: General anesthesia in a patient on long-term amphetamine therapy: is there cause for concern?
abstract: Amphetamines are powerful, sympathomimetic amines that, when used chronically, can profoundly effect a patient's cardiovascular stability during anesthesia and surgery. Amphetamines are the third most widely abused class of drugs in the United States. They also have legitimate medical use for attention deficit disorder with hyperactivity, exogenous obesity, and narcolepsy. We report a case of a patient with a 40-yr history of chronic amphetamine use having undergone two general anesthesias without complication.
authors.affiliation: Department of Anesthesia, Stanford University School of Medicine, CA 94305-5640, USA.
authors.forename: S P
authors.initials: SP
authors.lastname: Fischer
authors.forename: J M
authors.initials: JM
authors.lastname: Healzer
authors.forename: M W
authors.initials: MW
authors.lastname: Brook
authors.forename: J G
authors.initials: JG
authors.lastname: Brock-Utne
mesh_terms: D000661:Amphetamine / Q000009:adverse effects* / Q000627:therapeutic use; D000732:Androstanols; D000768:Anesthesia, General; D000697:Central Nervous System Stimulants / Q000009:adverse effects* / Q000627:therapeutic use; D004632:Emergency Medical Services; D006801:Humans; D007415:Intestinal Obstruction / Q000601:surgery; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009290:Narcolepsy / Q000150:complications / Q000188:drug therapy; D003473:Neuromuscular Nondepolarizing Agents; D011229:Preanesthetic Medication; D000077123:Rocuronium
chemical_list: D000732:Androstanols; D000697:Central Nervous System Stimulants; D003473:Neuromuscular Nondepolarizing Agents; D000661:Amphetamine; D000077123:Rocuronium