title: [ES-IPO-97 treatment protocol for prognostically poor Ewing's sarcoma forms in children: results of implementation].
abstract: The paper shows the high efficiency and moderate toxicity of inductive treatment in children with Young sarcoma and primitive neuroectodermal tumors by ES-Ipo-97 protocol that includes alternate chemotherapy by the scheme: vincristine, 1.5 mg/m2/day, on days 1, 8, 15; adriamycin, 37.5 mg/m2/day, on days 1 and 2 as 24-hour infusion; cyclophosphanum, 2.1 g/m2/day, on days 1 and 2 (Block A); iphosphamide, 2.4 g/m2/day on days 1 to 5, etoposide, 100 mg/m2/day, on days 1-5 (Block B). It provides evidence for that this therapy is promising and awaits further developments.
authors.forename: E A
authors.initials: EA
authors.lastname: Ptushkina
authors.forename: N M
authors.initials: NM
authors.lastname: Ivanova
authors.forename: I S
authors.initials: IS
authors.lastname: Dolgopolov
authors.forename: D G
authors.initials: DG
authors.lastname: Izhogin
authors.forename: A S
authors.initials: AS
authors.lastname: Petrosian
authors.forename: I V
authors.initials: IV
authors.lastname: Glekov
authors.forename: L A
authors.initials: LA
authors.lastname: Durnov
authors.forename: G L
authors.initials: GL
authors.lastname: Mentkevich
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D004333:Drug Administration Routes; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D012512:Sarcoma, Ewing / Q000188:drug therapy* / Q000473:pathology; D012720:Severity of Illness Index