[Familial hemiplegic migraine of childhood].
Familial hemiplegic migraine is a rare autosomal, dominant, migraine subtype. It is characterized by acute episodes of hemiplegia and hemisensory deficits, and other neurological abnormalities occurring either before or together with severe headache, nausea and vomiting; episodes last several hours and then spontaneously subside. Intervals between episodes are relatively prolonged. Unless there is a relevant family history suggesting this syndrome, the diagnosis is usually delayed. Recently the gene for the syndrome was identified on chromosome 19. We report 3 boys and 1 girl, 11-15 years old with hemiplegic migraine.
Livne
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Pediatric Division, Assaf Harofeh Medical Center, Tel Aviv University.
Lahat
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E
D000293:Adolescent; D000328:Adult; D002648:Child; D002874:Chromosome Mapping; D002888:Chromosomes, Human, Pair 19; D006801:Humans; D008297:Male; D020325:Migraine with Aura / Q000235:genetics* / Q000503:physiopathology