Malignant melanoma, dysplastic melanocytic nevi, and Spitz tumors. Histologic classification and characteristics.
The classification and pertinent histopathologic features of cutaneous melanoma, dysplastic melanocytic nevi, and Spitz tumors are presented. A discussion on melanoma emphasizes an objective approach to classification based on histomorphologic features including location in the skin, disposition and frequency of melanocytes, other specific morphologic features, and cell type. Other topics addressed include common and unusual variants of melanoma, the use of immunohistochemistry, and the histopathologic reporting of melanoma.
Barnhill
R L
RL
Pathology Services, Incorporated, Cambridge, Massachusetts, USA.
D000293:Adolescent; D000367:Age Factors; D002648:Child; D004416:Dysplastic Nevus Syndrome / Q000145:classification / Q000473:pathology*; D006801:Humans; D018327:Hutchinson's Melanotic Freckle / Q000145:classification / Q000473:pathology; D007150:Immunohistochemistry; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000145:classification / Q000473:pathology* / Q000556:secondary; D009361:Neoplasm Invasiveness; D018332:Nevus, Epithelioid and Spindle Cell / Q000145:classification / Q000473:pathology*; D009508:Nevus, Pigmented / Q000145:classification / Q000473:pathology*; D012878:Skin Neoplasms / Q000145:classification / Q000473:pathology*