title: Energy expenditure after surgical repair in children with cyanotic congenital heart disease.
abstract: OBJECTIVE
  Infants with cyanotic congenital heart disease (CCHD) have previously been shown to have similar resting energy expenditures (REEs) and elevated total energy expenditures (TEEs) compared with age-matched healthy infants. The purpose of this investigation was to re-examine the REE and TEE of the same individuals at 5 years of age, after surgical repair of the heart defect was done, to determine whether metabolic differences persist.
  
  
  METHODS
  Seven children were studied approximately 2.6 years after they underwent surgical repair of CCHD along with 10 age-matched healthy children. Indirect calorimetry was used to determine REE, and the doubly labeled water method was used to determine TEE and body composition.
  
  
  RESULTS
  Results were compared with single-factor repeated measures analysis of variance. No significant differences were found between groups in weight or body composition. No significant differences were found between groups in REE, TEE, or the energy expended in physical activity.
  
  
  CONCLUSIONS
  We conclude that differences in TEE observed during infancy are no longer present in 5-year-old children after they undergo surgical repair of CCHD. Furthermore, the individual components of energy expenditure of children with CCHD after repair are indistinguishable from those of healthy age-matched children.
authors.affiliation: Department of Pediatrics, Section of Neonatal-Perinatal Medicine, Indiana University School of Medicine, Indianapolis, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Leitch
authors.forename: C A
authors.initials: CA
authors.lastname: Karn
authors.forename: G J
authors.initials: GJ
authors.lastname: Ensing
authors.forename: S C
authors.initials: SC
authors.lastname: Denne
mesh_terms: D000704:Analysis of Variance; D000886:Anthropometry; D001823:Body Composition; D016022:Case-Control Studies; D002675:Child, Preschool; D004734:Energy Metabolism; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000378:metabolism* / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D012146:Rest