Structure determination of carboxyhomoyessotoxin, a new yessotoxin analogue isolated from adriatic mussels.
The contamination of shellfish with marine biotoxins derived from microalgae represents a serious problem for shellfish industries and public health. This study investigated the composition of diarrhetic shellfish toxins in the digestive glands of mussels from the Northern Adriatic Sea. Along with known yessotoxins, identified by comparison of their chromatographic and spectral properties with those reported in the literature, we isolated a new analogue of yessotoxin, carboxyhomoyessotoxin, whose structure was determined by mass spectrometry and (1)H NMR spectroscopy.
Ciminiello
P
P
Dipartimento di Chimica delle Sostanze Naturali, Università degli studi di Napoli "Federico II", via D. Montesano 49, 80131 Napoli, Italy. ciminiel@unina.it
Fattorusso
E
E
Forino
M
M
Poletti
R
R
Viviani
R
R
D000818:Animals; D049872:Bivalvia / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004988:Ethers, Cyclic / Q000737:chemistry* / Q000302:isolation & purification; D005088:Exocrine Glands / Q000737:chemistry; D007558:Italy; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D008978:Mollusk Venoms / Q000737:chemistry* / Q000302:isolation & purification; D035964:Oxocins
D004988:Ethers, Cyclic; D008978:Mollusk Venoms; D035964:Oxocins; C413504:carboxyhomoyessotoxin; C066632:yessotoxin