Improved growth velocity with intensive dialysis. Consequence or coincidence?
Growth failure in children with end-stage renal disease remains a difficult problem. A 2.5-month-old baby in renal failure due to primary hyperoxaluria type I received intensive dialysis aimed at decreasing oxalate tissue accretion. Over 5.5 months, while awaiting transplantation, his growth velocity was 29 cm/year compared with an average 4 cm/year in infants on hemodialysis and 22 cm/year in normal infants of this age. This remarkable growth rate, which could have represented catch-up growth, is hypothesized to be related to the delivered dialysis dose. It is suggested that this relationship be evaluated in a prospective randomized trial.
Katz
A
A
Department of Pediatrics, University of Minnesota, Minneapolis 55455-0392, USA.
Bock
G H
GH
Mauer
M
M
D006128:Growth / Q000502:physiology*; D006130:Growth Disorders / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D006960:Hyperoxaluria, Primary / Q000503:physiopathology* / Q000628:therapy; D007223:Infant; D007676:Kidney Failure, Chronic / Q000209:etiology* / Q000601:surgery / Q000628:therapy*; D016030:Kidney Transplantation; D008297:Male; D010531:Peritoneal Dialysis, Continuous Ambulatory