The effects of J modulation on spin-echo acquisition and calculation of spin-spin relaxation time (T2) from the J-suppressed data set.
The effects of J modulation on localized 1H NMR spectra were observed on metabolites with both a short T2 relaxation time like glutamate and a comparatively long T2 relaxation time like N-acetyl-L-aspartic acid (NAA). All examinations were performed by either the double spin-echo (PRESS) sequence or J-suppressed PRESS (JPRESS) sequence. Both of the sequences allow spectral editing and relaxation time studies of J coupled spins. Water-suppressed proton spectra were obtained at 1.5 T (GE Signa) from a 6-8 ml volume of interest. T1 and T2 relaxation times of some of the major brain metabolites were obtained by varying the repetition time and echo time of the JPRESS sequence.
Yaman
A
A
Ankara University Faculty of Sciences, Department of Physics, 06100, Tandogan/Ankara, Turkey.
D000465:Algorithms; D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000032:analysis* / Q000737:chemistry*; D018698:Glutamic Acid / Q000032:analysis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D011522:Protons
D011522:Protons; D001224:Aspartic Acid; D018698:Glutamic Acid; C000179:N-acetylaspartate