title: High frequency of metastatic Leydig cell testicular tumours.
abstract: 690 patients were treated for testicular tumour in the course of 18 years. The histology of 7 cases showed Leydig cell tumour. In 4 of the 7 cases, a metastatic process leading to death was observed. At the time of diagnosis, 5 patients were found to have low stage, whereas 2 of the patients had advanced lymphatic involvement. The hematogenous and lymphatic metastases proved to be resistant to chemotherapy. Contrary to the major part of the literature, retroperitoneal lymphadenectomy should be performed with this histological type for the exact pathological staging immediately following orchiectomy.
authors.affiliation: Department of Urology, Medical School of Pécs University, Pécs, Hungary.
authors.forename: L M
authors.initials: LM
authors.lastname: Farkas
authors.forename: J G
authors.initials: JG
authors.lastname: Székely
authors.forename: C
authors.initials: C
authors.lastname: Pusztai
authors.forename: M
authors.initials: M
authors.lastname: Baki
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols; D001761:Bleomycin / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D006801:Humans; D007984:Leydig Cell Tumor / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D014747:Vinblastine / Q000627:therapeutic use
chemical_list: D001761:Bleomycin; D014747:Vinblastine; D002945:Cisplatin