title: [Value of the 'non-diagnostic' lung scan--further classification as to the risk of pulmonary embolism not reliable].
abstract: OBJECTIVE
  To determine to what extent the 'non-diagnostic' lung scans made because of a clinical suspicion of pulmonary embolism enable further determination of the risk of pulmonary embolism.
  
  
  METHODS
  Retrospective.
  
  
  METHODS
  All non-diagnostic lung perfusion ventilation scans made in the Academic Medical Centre of Amsterdam in 1997 of 114 patients in succession (55 males and 59 females aged 27-85 years) were subjected to blind and independent re-evaluation by three observers (an experienced nuclear medicine expert, an experienced and an inexperienced intern) who, using a lung segment chart, estimated the risk of embolism as < 25%, 25-50%, 50-75% and > 75%. They did this first without and then with the chest X-ray. The findings were grouped on the basis of accordance or non-accordance with the pulmonary angiogram. The interobserver agreement was calculated by means of kappa statistics.
  
  
  RESULTS
  Of 58 patients the lung scan could be compared with a chest X-ray and a pulmonary angiogram. In 43 patients with a normal angiogram the observers in an average of 50% of the scans estimated the risk of pulmonary embolism as < 25%, as against 25-50% in 27%, 50-75% in 9% and > 75% in 5%. In 15 patients with a deviant pulmonary angiogram, these figures were 22%, 38%, 20%, and 12%, respectively. The interobserver kappa for evaluation without chest X-ray was < or = 0.16, as against < or = 0.41% with the chest X-ray.
  
  
  CONCLUSIONS
  A reliable classification of the risk of pulmonary embolism was not possible on the basis of non-diagnostic lung scans, regardless of whether the patient did or did not have pulmonary embolism. The interobserver variability was less when the lung scan was evaluated together with the chest X-ray, but even so it was unacceptably high.
authors.affiliation: Afd. Nucleaire Geneeskunde, Academisch Medisch Centrum, Amsterdam.
authors.forename: H S
authors.initials: HS
authors.lastname: Broekhuizen-de Gast
authors.forename: M M
authors.initials: MM
authors.lastname: Tiel-van Buul
authors.forename: M
authors.initials: M
authors.lastname: Ubbink
authors.forename: B L
authors.initials: BL
authors.lastname: van Eck-Smit
authors.forename: H R
authors.initials: HR
authors.lastname: Büller
authors.forename: E J
authors.initials: EJ
authors.lastname: van Beek
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011875:Radionuclide Angiography / Q000379:methods / Q000592:standards*; D012189:Retrospective Studies; D018570:Risk Assessment; D014057:Tomography, X-Ray Computed; D014692:Ventilation-Perfusion Ratio