title: Necrotizing fasciitis.
abstract: A 31-year-old Pakistani man was admitted to hospital after sustaining a Grade I compound fracture of the mid-shaft of the left tibia and fibula following a motor vehicle accident. He developed septicaemic shock, acute renal failure and Group A streptococcal necrotizing fasciitis of the left leg. The patient underwent an above knee amputation followed by disarticulation of the left hip with extensive debridement. He was treated with benzylpenicillin, vancomycin, inotropes and continuous haemodialysis and survived without further sequelae. Subsequently, skin grafting was done over the wound site. This case highlights the role of Group A streptococcus as a cause of this rare and life-threatening infection.
authors.affiliation: Department of Medical Microbiology and Immunology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur.
authors.forename: A W
authors.initials: AW
authors.lastname: Zubaidah
authors.forename: V K
authors.initials: VK
authors.lastname: Lim
mesh_terms: D000328:Adult; D000671:Amputation, Surgical; D003646:Debridement; D019115:Fasciitis, Necrotizing / Q000209:etiology*; D006621:Hip Joint / Q000601:surgery; D006801:Humans; D007869:Leg Injuries / Q000601:surgery*; D008297:Male; D013530:Surgical Wound Infection / Q000150:complications* / Q000601:surgery