title: Optic nerve sheath fenestration for a reversible optic neuropathy in radiation oncology.
abstract: To the authors' knowledge, there is a paucity of published accounts of management of radiation-induced optic neuropathy (RION) by optic nerve sheath fenestration (ONSF) in the conventional medical literature. With higher doses of radiation being given by using conformal techniques, more radiation-induced optic neuritis and neuropathy will be identified. We report here the successful use of ONSF to restore vision to three consecutive patients with pending anterior RION, and the importance of early identification and intervention in these potentially reversible cases.
authors.affiliation: Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
authors.forename: I G
authors.initials: IG
authors.lastname: Mohamed
authors.forename: W
authors.initials: W
authors.lastname: Roa
authors.forename: D
authors.initials: D
authors.lastname: Fulton
authors.forename: S
authors.initials: S
authors.lastname: Halls
authors.forename: N
authors.initials: N
authors.lastname: Jha
authors.forename: A
authors.initials: A
authors.lastname: Kherani
authors.forename: R
authors.initials: R
authors.lastname: Johnson
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy; D005260:Female; D005625:Frontal Lobe / Q000528:radiation effects / Q000601:surgery; D005909:Glioblastoma / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008297:Male; D009441:Neurilemma; D009837:Oligodendroglioma / Q000532:radiotherapy / Q000601:surgery; D009900:Optic Nerve / Q000601:surgery*; D009901:Optic Nerve Diseases / Q000209:etiology / Q000601:surgery*; D009902:Optic Neuritis / Q000209:etiology / Q000601:surgery; D011832:Radiation Injuries / Q000209:etiology / Q000601:surgery*; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000009:adverse effects*; D012888:Skull Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D013702:Temporal Lobe / Q000528:radiation effects / Q000601:surgery; D014785:Vision, Ocular / Q000502:physiology; D014792:Visual Acuity / Q000528:radiation effects