title: Major leg wound complications after saphenous vein harvest for coronary revascularization.
abstract: BACKGROUND
  Major leg wound complications after coronary artery bypass graft procedures are infrequent and few are reported in the literature. We present our experience in treating 23 patients with major leg wound complications after coronary revascularization procedures.
  
  
  METHODS
  A retrospective review of 3,525 bypass procedures with saphenous vein grafts performed over a 10-year period was conducted. Ten potential risk factors for those who developed major leg wound complications were analyzed and compared with the entire cohort of patients undergoing similar bypass procedures during the same period.
  
  
  RESULTS
  Lower extremity wound complications occurred in 145 patients (4.1%), 23 of whom (0.65%) required additional surgical interventions (62 total). There were 32 wound debridements, 8 skin grafts, 11 vascular procedures, 5 amputations, 3 fasciotomies, 2 free tissue transfers, and 1 fasciocutaneous flap. Of ten variables evaluated by multivariate analysis, female gender, peripheral vascular disease, and postoperative intraaortic balloon pump use were identified as significant independent predictors of major leg wound complications (p < 0.0001).
  
  
  CONCLUSIONS
  The causes of major leg wound complications after saphenous vein harvest for coronary artery bypass graft procedures are multifactorial. To minimize these complications, we recommend vascular evaluations before saphenous vein harvest, attention to proper surgical technique, and careful harvest site selection.
authors.affiliation: Division of Plastic and Reconstructive Surgery, Saint Louis University School of Medicine, Missouri 63110-0250, USA. palettac@slu.edu
authors.forename: C E
authors.initials: CE
authors.lastname: Paletta
authors.forename: D B
authors.initials: DB
authors.lastname: Huang
authors.forename: A C
authors.initials: AC
authors.lastname: Fiore
authors.forename: M T
authors.initials: MT
authors.lastname: Swartz
authors.forename: F L
authors.initials: FL
authors.lastname: Rilloraza
authors.forename: J E
authors.initials: JE
authors.lastname: Gardner
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass; D005260:Female; D006801:Humans; D007866:Leg; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors; D012501:Saphenous Vein / Q000637:transplantation*; D012883:Skin Ulcer / Q000209:etiology; D013530:Surgical Wound Infection / Q000209:etiology; D020858:Tissue and Organ Harvesting; D014656:Vascular Surgical Procedures / Q000009:adverse effects*; D014945:Wound Healing