Adrenal ganglioneuroma: a familial case.
A 67-year-old woman was evaluated for asymptomatic microscopic hematuria. Intravenous urography and computed tomography demonstrated an adrenal mass, but the workup for a functional adrenal tumor was negative. The mass was surgically resected, with a histologic diagnosis of adrenal ganglioneuroma. No further treatment was necessary. After the diagnosis was made, the patient reported a family history positive for neuroblastic tumors. Two of her grandchildren had presented at early ages with a ganglioneuroblastoma and a third had presented with a ganglioneuroma. This presentation is unique because ganglioneuroma, especially that of adrenal origin, is rare in the adult population, and familial cases are extremely uncommon.
Leavitt
J R
JR
Department of Surgery, St. Joseph Mercy Hospital, Pontiac, Michigan, USA.
Harold
D L
DL
Robinson
R B
RB
D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D000368:Aged; D002648:Child; D005260:Female; D005729:Ganglioneuroma / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D020022:Genetic Predisposition to Disease; D006801:Humans; D007223:Infant; D010375:Pedigree