Colonic type adenocarcinoma of male urethra.
A case of rare primary adenocarcinoma of the bulbomembranous portion of the male urethra is presented. The histological and immunohistochemical characteristics of this tumor are identical to those of colon adenocarcinomas. The pathogenesis can be explained either by neoplastic degeneration of globet cells found in the urethral epithelium or by malignant degeneration of persistent glandular elements that are embryonal residues. The patient was successfully treated with transurethral prostatectomy and with a high dose of radiation therapy.
Baldi
A
A
Laboratory for Cell Metabolism and Pharmacokinetics, Regina Elena Cancer Institute, Rome.
Rossiello
R
R
Di Marino
M
M
Ferrara
N
N
Groeger
A M
AM
Esposito
V
V
Santini
D
D
Kaiser
H E
HE
Baldi
F
F
D000230:Adenocarcinoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D003110:Colonic Neoplasms / Q000473:pathology*; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011468:Prostatectomy; D014521:Urethra / Q000473:pathology; D014523:Urethral Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D019459:Urothelium / Q000473:pathology