title: Heparin-induced thrombocytopenia (HIT): in vitro and in vivo cross-reactivity to danaparoid sodium and successful treatment with recombinant hirudin (lepirudin)
authors.forename: M W
authors.initials: MW
authors.lastname: Baumgärtel
authors.forename: P
authors.initials: P
authors.lastname: Eichler
authors.forename: W M
authors.initials: WM
authors.lastname: Glöckner
authors.forename: O
authors.initials: O
authors.lastname: Ranze
authors.forename: A
authors.initials: A
authors.lastname: Greinacher
mesh_terms: D000906:Antibodies / Q000276:immunology; D000925:Anticoagulants / Q000009:adverse effects / Q000276:immunology / Q000627:therapeutic use*; D002809:Chondroitin Sulfates / Q000276:immunology* / Q000627:therapeutic use; D003429:Cross Reactions; D003871:Dermatan Sulfate / Q000276:immunology* / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D006493:Heparin / Q000009:adverse effects*; D006497:Heparan Sulfate / Q000276:immunology* / Q000627:therapeutic use; D024764:Hirudin Therapy; D006629:Hirudins / Q000031:analogs & derivatives*; D006801:Humans; D008875:Middle Aged; D011994:Recombinant Proteins / Q000627:therapeutic use*; D013921:Thrombocytopenia / Q000139:chemically induced / Q000188:drug therapy* / Q000276:immunology
chemical_list: D000906:Antibodies; D000925:Anticoagulants; D002809:Chondroitin Sulfates; D003871:Dermatan Sulfate; D004338:Drug Combinations; D006493:Heparin; D006497:Heparan Sulfate; D006629:Hirudins; D011994:Recombinant Proteins; C035838:danaparoid; C083544:lepirudin