Effect of Streptococcus thermophilus on the trp-P-1 level in the blood.
We examined the 3-amino-1,4-dimethyl-5H-Pyrido-[4,3-b]indole (Trp-P-1) concentration in the blood after administering Trp-P-1 (0.25 mg/ml) with or without Streptococcus thermophilus 1131 cells (10 mg/ml) to rats. The Trp-P-1 concentration in the blood from the portal vein was significantly lower in the rats that had been administered with Trp-P-1 with the strain 1131 cells than without them. However, there was no difference in the Trp-P-1 concentration in the blood taken from the abdominal aorta of these rats.
Terahara
M
M
Food Functionality Research Institute, Meiji Milk Products Co. Ltd., Higashimurayama, Tokyo, Japan.
Nishide
S
S
Kaneko
T
T
D000818:Animals; D002243:Carbolines / Q000008:administration & dosage / Q000097:blood*; D002273:Carcinogens / Q000008:administration & dosage / Q000032:analysis*; D008297:Male; D051381:Rats; D011916:Rats, Inbred F344; D013291:Streptococcus / Q000502:physiology*
D002243:Carbolines; D002273:Carcinogens; C019132:3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole