title: [Severe exposure to environmental lead in a child population in Antofagasta, Chile].
abstract: BACKGROUND
  In Antofagasta, Chile, lead is gathered in bulk in urban zones, contaminating surrounding schools and houses.
  
  
  OBJECTIVE
  To verify if the environmental lead exposure results in high blood lead levels in children living near lead storage sites.
  
  
  METHODS
  Four hundred eighty-six children under 7 years old, living near lead storage sites and 75 children living far away form these sites, were studied. An inquiry was applied and venous blood was drawn. Air, soil and water lead concentrations were also measured.
  
  
  RESULTS
  Lead geometric mean concentrations in exposed children were 8.7 micrograms/dL and 4.22 micrograms/dL in unexposed children. Forty seven percent of exposed children and no unexposed children had lead levels over 10 micrograms/dL. The distance of dwellings from lead storage sites, their geographic location and their antiquity were significantly associated with high blood lead levels. Multivariate models disclosed that people living in contaminated sites have an odds ratio of 24.9 for high blood lead levels.
  
  
  CONCLUSIONS
  Environmental lead contamination is significantly associated with high blood lead levels.
authors.affiliation: Departamento de Programas sobre el Ambiente, Facultad de Medicina, Pontificia Universidad Católica de Chile.
authors.forename: V
authors.initials: V
authors.lastname: Sepúlveda
authors.forename: J
authors.initials: J
authors.lastname: Vega
authors.forename: I
authors.initials: I
authors.lastname: Delgado
mesh_terms: D000704:Analysis of Variance; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002677:Chile / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004781:Environmental Exposure / Q000009:adverse effects*; D004784:Environmental Monitoring; D062665:Epidemiological Monitoring; D005260:Female; D006798:Housing; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007854:Lead / Q000097:blood*; D007855:Lead Poisoning / Q000453:epidemiology*; D016014:Linear Models; D008297:Male; D015995:Prevalence; D012111:Residence Characteristics; D012307:Risk Factors; D012959:Socioeconomic Factors
chemical_list: D007854:Lead