Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist.
Pseudomonas aeruginosa is an ubiquitous pathogen capable of infecting virtually all tissues. A large variety of virulence factors contribute to its importance in burn wounds, lung infection and eye infection. Prominent factors include pili, flagella, lipopolysaccharide, proteases, quorum sensing, exotoxin A and exoenzymes secreted by the type III secretion system.
Lyczak
J B
JB
The Channing Laboratory, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.
Cannon
C L
CL
Pier
G B
GB
D000818:Animals; D002056:Burns / Q000382:microbiology; D002237:Carbohydrate Dehydrogenases / Q000235:genetics; D003320:Corneal Ulcer / Q000382:microbiology; D003428:Cross Infection / Q000382:microbiology; D003550:Cystic Fibrosis / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000382:microbiology; D006801:Humans; D009894:Opportunistic Infections / Q000382:microbiology; D011552:Pseudomonas Infections / Q000276:immunology / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000201:enzymology / Q000235:genetics / Q000472:pathogenicity*; D012141:Respiratory Tract Infections / Q000382:microbiology; D014774:Virulence
D002237:Carbohydrate Dehydrogenases; C020562:GDPmannose dehydrogenase