title: Contribution to the choice of therapy in abdominal pregnancy.
abstract: The goal of our study was to offer our contribution to the selection of the most suitable therapy to treat abdominal pregnancy. We discuss three patients affected with this pathology, which was diagnosed early by laparoscopy. The patients were treated with 50 mg/m2 of methotrexate administered intravenously. The abdominal pregnancy was terminated in all three patients. Since the outcome involved termination of the pregnancy, it is important to emphasize that methotrexate therapy, must be considered elective. Operative laparoscopy can be limited only to cases in which the ovum has not become implanted in the intestinal interstices and is not near sites susceptible to complications.
authors.affiliation: Second University of Naples, School of Medicine, Department of Gynecology and Obstetrics, Naples, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Cobellis
authors.forename: L
authors.initials: L
authors.lastname: Stradella
authors.forename: E M
authors.initials: EM
authors.lastname: Messalli
mesh_terms: D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008727:Methotrexate / Q000627:therapeutic use*; D011247:Pregnancy; D011269:Pregnancy, Abdominal / Q000188:drug therapy*
chemical_list: D000964:Antimetabolites, Antineoplastic; D008727:Methotrexate