title: Hypothyroidism and primary open-angle glaucoma.
abstract: OBJECTIVE
  To test if there is an association between hypothyroidism and primary open-angle glaucoma (POAG) and the utility of routine study of thyroid function in these patients.
  
  
  METHODS
  The study was conducted in a case-control fashion. Seventy-five consecutive patients with a previous diagnosis of POAG and 75 control patients were prospectively evaluated for hypothyroidism. The levels of thyroid-stimulating hormone and free thyroxin were measured.
  
  
  RESULTS
  Hypothyroidism was revealed in only 2 patients with previous diagnosis of POAG (2.67%) and 3 patients of the control group (4%).
  
  
  CONCLUSIONS
  As we have not been able to demonstrate the previously reported relationship between hypothyroidism and POAG, we cannot recommend the systematic screening for hypothyroidism in patients with POAG.
authors.affiliation: Department of Ophthalmology, Ramón y Cajal Hospital, Madrid, Spain. FJMUNOZ@santandersupernet.com
authors.forename: F J
authors.initials: FJ
authors.lastname: Muñoz-Negrete
authors.forename: G
authors.initials: G
authors.lastname: Rebolleda
authors.forename: F
authors.initials: F
authors.lastname: Almodóvar
authors.forename: B
authors.initials: B
authors.lastname: Díaz
authors.forename: C
authors.initials: C
authors.lastname: Varela
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D005902:Glaucoma, Open-Angle / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D013030:Spain / Q000453:epidemiology; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D015415:Biomarkers; D013972:Thyrotropin; D013974:Thyroxine