[Blistering drug reactions].
The occurrence of erosions on the mucous membranes and (or) blisters on the skin usually indicates the seriousness of an adverse drug reaction. This paper will review the clinical and histological presentation, drug causes, and prognosis of blistering drug eruptions, with special focus on the most severe: Stevens-Johnson syndrome and Toxic epidermal necrolysis.
Roujeau
J C
JC
Service de dermatologie Hôpital Henri-Mondor, Créteil. jean-claude.roujeau@hmn.ap-hop-paris.fr
D001768:Blister / Q000139:chemically induced*; D003875:Drug Eruptions / Q000209:etiology* / Q000503:physiopathology; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D011379:Prognosis; D012720:Severity of Illness Index; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced / Q000209:etiology / Q000503:physiopathology