title: Bacillus subtilis YvrK is an acid-induced oxalate decarboxylase.
abstract: Bacillus subtilis has been shown to express a cytosolic oxalate decarboxylase (EC 4.1.1.2). The enzyme was induced in acidic growth media, particularly at pH 5.0, but not by oxalate. The enzyme was purified, and N-terminal sequencing identified the protein to be encoded by yvrK. The role of the first oxalate decarboxylase to be identified in a prokaryote is discussed.
authors.affiliation: Biological Chemistry Department, John Innes Centre, Norwich Research Park, Colney, United Kingdom.
authors.forename: A
authors.initials: A
authors.lastname: Tanner
authors.forename: S
authors.initials: S
authors.lastname: Bornemann
mesh_terms: D000595:Amino Acid Sequence; D001412:Bacillus subtilis / Q000201:enzymology* / Q000254:growth & development; D002262:Carboxy-Lyases / Q000096:biosynthesis / Q000737:chemistry* / Q000378:metabolism*; D003470:Culture Media; D003600:Cytosol / Q000201:enzymology; D004790:Enzyme Induction; D006863:Hydrogen-Ion Concentration; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
chemical_list: D003470:Culture Media; D002262:Carboxy-Lyases; C021915:oxalate decarboxylase