[The joint changes and presence of HLA-B27 antigen in patients with ulcerative colitis].
The extra-bowel manifestation can be found among patients with ulcerative colitis (UC). The most common are the joint changes. A group of 18 patients with ulcerative colitis was investigated. The physical and radiological signs of joint inflammation and presence of HLA-B27 antigen in blood were examined. Appearance of HLA-B27 antigen among 28% of patients with ulcerative colitis can support involvement of autoimmunologic mechanism in joint inflammation. The joint changes (swelling of small joints of hand, presence of nodes, sacroileitis, and particularly spondyloarthritis) were observed in 50% of patients.
Lapiński
T W
TW
Kliniki Obserwacyjno-Zakaźnej AM w Białymstoku.
Prokopowicz
D
D
Lapińska
L
L
Kuryliszyn-Moskal
A
A
Puzanowska
B
B
D000328:Adult; D003093:Colitis, Ulcerative / Q000150:complications* / Q000276:immunology*; D005260:Female; D015796:HLA-B27 Antigen / Q000276:immunology*; D006801:Humans; D007592:Joint Diseases / Q000150:complications* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged
D015796:HLA-B27 Antigen