title: Homocysteine: a history in progress.
abstract: This paper shows that the linkage between basic science and clinical research has characterized the field of sulfur amino acid metabolism since 1810, when Wollaston isolated cystine from a human bladder stone. The nature and consequences of this relationship are discussed.
authors.affiliation: Veterans Affairs Medical Center, George Washington University, DC 20422, USA.
authors.forename: J D
authors.initials: JD
authors.lastname: Finkelstein
mesh_terms: D049672:History, 19th Century; D049673:History, 20th Century; D006710:Homocysteine / Q000032:analysis / Q000266:history* / Q000378:metabolism; D006712:Homocystinuria / Q000201:enzymology / Q000266:history; D006801:Humans; D007328:Insulin / Q000737:chemistry / Q000266:history; D008715:Methionine / Q000032:analysis / Q000737:chemistry / Q000266:history; D009436:Neural Tube Defects / Q000266:history; D009656:North America; D012106:Research / Q000266:history*; D012436:S-Adenosylmethionine / Q000032:analysis / Q000737:chemistry / Q000266:history; D000078329:Workforce
chemical_list: D007328:Insulin; D006710:Homocysteine; D012436:S-Adenosylmethionine; D008715:Methionine