The molecular genetics of human herpesvirus 8.
Epidemiological evidence from the early 1990s suggested that a sexually transmitted infectious agent other than the HIV virus was associated with the development of Kaposi's sarcoma in patients with HIV. A novel gamma herpesvirus was identified in Kaposi's sarcoma lesions. The molecular genetics of this virus are reviewed in this article.
Gill
J
J
Department of HIV Medicine, Westminster Hospital, London.
Powles
T
T
Bower
M
M
D017088:AIDS-Related Opportunistic Infections / Q000821:virology*; D053446:CASP8 and FADD-Like Apoptosis Regulating Protein; D002352:Carrier Proteins / Q000235:genetics; D056741:Cyclin D; D016213:Cyclins / Q000235:genetics; D019254:Genes, bcl-2 / Q000235:genetics; D019288:Herpesvirus 8, Human / Q000235:genetics*; D006801:Humans; D015850:Interleukin-6 / Q000235:genetics; D047908:Intracellular Signaling Peptides and Proteins; D019402:Macrophage Inflammatory Proteins / Q000235:genetics; D011956:Receptors, Cell Surface / Q000235:genetics; D012514:Sarcoma, Kaposi / Q000821:virology*; D012878:Skin Neoplasms / Q000821:virology*
D053446:CASP8 and FADD-Like Apoptosis Regulating Protein; C506386:CFLAR protein, human; D002352:Carrier Proteins; D056741:Cyclin D; D016213:Cyclins; D015850:Interleukin-6; D047908:Intracellular Signaling Peptides and Proteins; D019402:Macrophage Inflammatory Proteins; D011956:Receptors, Cell Surface