title: Healing of superior vena cava defect in mediastinal seminoma with invasion.
abstract: We present an unusual case of mediastinal seminoma with direct intraluminal invasion into the superior vena cava (SVC) and extension to the right atrium. Magnetic resonance imaging demonstration of the SVC defect due to tumor invasion was important for determining treatment strategy because rapid posttherapeutic tumor regression may increase the risk of SVC rupture. Gradual healing of the SVC defect at the tumor entrance site was attained using a tailored treatment plan with radiotherapy and chemotherapy.
authors.affiliation: Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital, Taiwan, Republic of China.
authors.forename: F M
authors.initials: FM
authors.lastname: Fang
authors.forename: S F
authors.initials: SF
authors.lastname: Ko
authors.forename: C H
authors.initials: CH
authors.lastname: Hwang
authors.forename: C J
authors.initials: CJ
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D003131:Combined Modality Therapy; D006338:Heart Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D009361:Neoplasm Invasiveness; D018239:Seminoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D013479:Superior Vena Cava Syndrome / Q000209:etiology*; D014683:Vena Cava, Superior / Q000473:pathology