Corticosteroids in polymyalgia rheumatica--a review of different treatment schedules.
Low dose oral steroids (prednisolone 10-15 mg daily) are currently advocated for the treatment of uncomplicated PMR and the dose should be carefully adjusted in relation to disease activity. Intramuscular methylprednisolone has been shown to have a similar remission rate to oral steroids and a better side effect profile with respect to fracture rate and weight gain. Prophylaxis for osteoporosis at least with calcium and vitamin D should be initiated at the start of steroid therapy.
Li
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C
Department of Rheumatology, Southend Hospital, Westcliff-on-Sea, Essex, UK. dr.dasgupta@southend-hospital.thenhs.com
Dasgupta
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B
D004334:Drug Administration Schedule; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage*; D011111:Polymyalgia Rheumatica / Q000188:drug therapy*
D005938:Glucocorticoids; D008775:Methylprednisolone