The first synthesis of the pentacyclic pyridoacridine marine alkaloids: arnoamines A and B.
The synthesis of the marine pyridoacridine alkaloids arnoamines A and B has been accomplished in six and seven steps from 4-chloro-8-methoxy-5-nitroquinoline in 13% and 4% overall yield, respectively.
Delfourne
E
E
Centre de Phytopharmacie, UMRCNRS 5054 Universite de Perpignan, 52 avenue de Villeneuve, 66860 Perpignan Cedex, France. delfourn@univ-perp.fr
Roubin
C
C
Bastide
J
J
D000470:Alkaloids / Q000138:chemical synthesis*; D000818:Animals; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013057:Spectrum Analysis; D014561:Urochordata / Q000737:chemistry
D000470:Alkaloids; D011804:Quinolines; C413846:arnoamine A; C413847:arnoamine B