title: Splenic hemangiosarcoma. A case report.
abstract: Splenic hemangiosarcoma is a rare and aggressive tumor. Up to now, less than 150 cases have been reported. We describe a patient with a rapide course. The diagnosis of hemangiosarcoma was based on immunohistochemical tests (factor-VIII-associated antigen, CD31, CD34). Despite the improvement of diagnostic techniques, pathological examination and immunohistochemistry remain the only methods available for the diagnosis.
authors.affiliation: Istituto di Medicina Interna, Università Cattolica, Rome, Italy. melaniamanco@tiscalinet.it
authors.forename: M
authors.initials: M
authors.lastname: Manco
authors.forename: M
authors.initials: M
authors.lastname: Buononato
authors.forename: F
authors.initials: F
authors.lastname: Equitani
mesh_terms: D018952:Antigens, CD34 / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D005169:Factor VIII / Q000032:analysis; D005260:Female; D006394:Hemangiosarcoma / Q000737:chemistry / Q000175:diagnosis*; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis; D013160:Splenic Neoplasms / Q000737:chemistry / Q000175:diagnosis*
chemical_list: D018952:Antigens, CD34; D014408:Biomarkers, Tumor; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D005169:Factor VIII