title: [Disseminated acute encephalomyelitis with fatal evolution: clinicopathological study].
abstract: BACKGROUND
  Disseminated acute encephalomyelitis is a monophasic demyelinating disease which progresses rapidly and is often fatal. It is an autoimmune condition, mediated by T lymphocytes, in which the immune response is directed against the myelin antigens.
  
  
  METHODS
  We describe the clinical, radiological and neuropathological findings in the case of a 31 year old woman who, ten days after complaining of a clinical condition of upper respiratory tract inflammation, presented with unilateral focal neurological signs, subsequent rapid deterioration of consciousness and death. On autopsy the neuropathological characteristics of disseminated acute encephalomyelitis were seen.
  
  
  CONCLUSIONS
  The relative rarity of this condition at the present time makes clinical diagnosis difficult. The differential diagnosis with other conditions may be difficult also. Thus, this disease often leads to a neuropathological diagnosis.
authors.affiliation: Departamento de Anatomía Patológica, Hospital Vall d'Hebron, Universidad Autònoma de Barcelona, España. 12497aoa@comb.es
authors.forename: A
authors.initials: A
authors.lastname: Ortega-Aznar
authors.forename: F J
authors.initials: FJ
authors.lastname: Romero-Vidal
authors.forename: J
authors.initials: J
authors.lastname: Salvadó
mesh_terms: D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology*; D003937:Diagnosis, Differential; D018450:Disease Progression; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis* / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008218:Lymphocytosis / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D009175:Mycoplasma Infections; D014057:Tomography, X-Ray Computed