Comparison of a ligase chain reaction-based assay and cell culture for detection of pharyngeal carriage of Chlamydia trachomatis.
In 264 genitourinary medicine clinic attenders reporting recent fellatio, the prevalence of pharyngeal Chlamydia trachomatis determined by an expanded standard including cell culture and two in-house PCR tests was 1.5% in 194 women and zero in 70 men. The ligase chain reaction (Abbott LCx) had a specificity of 99.2% and a positive predictive value of 60%.
Winter
A J
AJ
Department of Genitourinary Medicine, Whittall St. Clinic, Birmingham, United Kingdom. Andy_Winter@talk21.com
Gilleran
G
G
Eastick
K
K
Ross
J D
JD
D000328:Adult; D001431:Bacteriological Techniques; D002353:Carrier State / Q000175:diagnosis* / Q000382:microbiology; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000235:genetics / Q000254:growth & development / Q000302:isolation & purification*; D003470:Culture Media; D005260:Female; D006801:Humans; D022521:Ligase Chain Reaction; D008297:Male; D010614:Pharynx / Q000382:microbiology*
D003470:Culture Media