title: Structure and function of cytochrome bc complexes.
abstract: The cytochrome bc complexes represent a phylogenetically diverse group of complexes of electron-transferring membrane proteins, most familiarly represented by the mitochondrial and bacterial bc1 complexes and the chloroplast and cyanobacterial b6f complex. All these complexes couple electron transfer to proton translocation across a closed lipid bilayer membrane, conserving the free energy released by the oxidation-reduction process in the form of an electrochemical proton gradient across the membrane. Recent exciting developments include the application of site-directed mutagenesis to define the role of conserved residues, and the emergence over the past five years of X-ray structures for several mitochondrial complexes, and for two important domains of the b6f complex.
authors.affiliation: Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA. EABerry@LBL.gov
authors.forename: E A
authors.initials: EA
authors.lastname: Berry
authors.forename: M
authors.initials: M
authors.lastname: Guergova-Kuras
authors.forename: L S
authors.initials: LS
authors.lastname: Huang
authors.forename: A R
authors.initials: AR
authors.lastname: Crofts
mesh_terms: D000818:Animals; D002736:Chloroplasts / Q000737:chemistry; D018360:Crystallography, X-Ray; D000458:Cyanobacteria / Q000737:chemistry; D004579:Electron Transport; D014450:Electron Transport Complex III / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D006873:Hydroquinones / Q000378:metabolism; D008958:Models, Molecular; D010084:Oxidation-Reduction; D010802:Phylogeny; D021122:Protein Subunits
chemical_list: D006873:Hydroquinones; D021122:Protein Subunits; D014450:Electron Transport Complex III