title: Severe combined immunodeficiency in a Malaysian child.
abstract: A 3-month-old Malay male infant presented with multiple infections (candidiasis, Pseudomonas aeruginosa, Cytomegalovirus), persistent pneumonia, intractable diarrhoea and failure to thrive. There was lymphopaenia affecting both T and B subsets. He developed Graft versus Host disease weeks following transfusion with non irradiated blood. In spite of aggressive microbicidal and supportive therapy including regular immunoglobulin infusions, the child succumbed to infection before a bone marrow transplant could be instituted.
authors.affiliation: Dept of Immunology, School of Medicine, Universiti Sains Malaysia, Kelantan.
authors.forename: L M
authors.initials: LM
authors.lastname: Noh
authors.forename: H L
authors.initials: HL
authors.lastname: Amir
authors.forename: L C
authors.initials: LC
authors.lastname: Hung
authors.forename: I
authors.initials: I
authors.lastname: Zulkifli
authors.forename: B A
authors.initials: BA
authors.lastname: Nasuruddin
mesh_terms: D006086:Graft vs Host Disease / Q000209:etiology; D006801:Humans; D007223:Infant; D008297:Male; D016511:Severe Combined Immunodeficiency / Q000150:complications / Q000276:immunology*