title: Separation of gallic acid from Cornus officinalis Sieb. et Zucc by high-speed counter-current chromatography.
abstract: Gallic acid was separated from a n-butanol extract of the fruit of Cornus officinalis Sieb. et Zucc by high-speed countercurrent chromatography in two steps using two solvent systems composed of ethyl-acetate-ethanol n-butanol-water (5:1.8:6, v/v/v) and ethyl acetate-ethanol-water (5:0.5:6, v/v/v) successively. From 1 g of n-butanol extract the method produced 60 mg of gallic acid at a purity of 97%.
authors.affiliation: Beijing Institute of New Technology Application, China.
authors.forename: G
authors.initials: G
authors.lastname: Tian
authors.forename: T
authors.initials: T
authors.lastname: Zhang
authors.forename: F
authors.initials: F
authors.lastname: Yang
authors.forename: Y
authors.initials: Y
authors.lastname: Ito
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005707:Gallic Acid / Q000302:isolation & purification*; D008516:Medicine, Chinese Traditional; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D005707:Gallic Acid