[Evaluation of the quality of mexiletine hydrochloride using capillary electrophoreses].
Mexiletine hydrochloride and its potential impurity xylenol were determined by micellar electrokinetic chromatography in a 25 cm long capillary. The effect of parameters--temperature, electric field, concentration of analyzed compounds, type and composition of background electrolyte--on the separation of analytes and precision of analysis was studied. The advantage of the elaborated method is a very short time of analysis (2.3 min) at the sufficient level of precision and reliability of results.
Proksa
B
B
Slovakofarma, a.s., Hlohovec.
Proksová
A
A
D000889:Anti-Arrhythmia Agents / Q000737:chemistry*; D019075:Electrophoresis, Capillary; D008801:Mexiletine / Q000737:chemistry*
D000889:Anti-Arrhythmia Agents; D008801:Mexiletine