title: Comparative In vitro activities of ertapenem (MK-0826) against 1,001 anaerobes isolated from human intra-abdominal infections.
abstract: By using an agar dilution method, the comparative in vitro activities of ertapenem (MK-0826) were studied against 1,001 anaerobes isolated from human intra-abdominal infections in 17 countries worldwide. MK-0826 was uniformly active against all isolates, including all Bacteroides fragilis group species isolates, with the exception of 12 of 61 (20%) strains of Bilophila wadsworthia, 3 strains of lactobacilli, and 1 isolate of Acidaminococcus fermentans. Geographical variation in activity was not observed.
authors.affiliation: R. M. Alden Research Laboratory, Santa Monica-University of California at Los Angeles Medical Center, 90404, USA. EJCGMD@aol.com
authors.forename: E J
authors.initials: EJ
authors.lastname: Goldstein
authors.forename: D M
authors.initials: DM
authors.lastname: Citron
authors.forename: C
authors.initials: C
authors.lastname: Vreni Merriam
authors.forename: Y
authors.initials: Y
authors.lastname: Warren
authors.forename: K L
authors.initials: KL
authors.lastname: Tyrrell
mesh_terms: D018784:Abdominal Abscess / Q000382:microbiology*; D001421:Bacteria, Anaerobic / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D001938:Brazil; D015780:Carbapenems / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D012426:Russia; D013019:South Africa; D013030:Spain
chemical_list: D015780:Carbapenems; C108047:L 749345