Poland's syndrome and recessive X-linked ichthyosis in two brothers.
Poland's syndrome consists of unilateral congenital absence of the pectoralis major muscle with a variable degree of ipsilateral upper limb deformity. The aetiology of Poland's syndrome is unknown, although an inherited tendency to develop a compromised embryonic vascular supply in the affected areas has been suggested. The majority of reported cases are sporadic, and in only a few instances is there a familial incidence. We describe the occurrence of Poland's syndrome in two brothers who also had recessive X-linked ichthyosis. To the best of our knowledge this is the first report of such an association.
Vélez
A
A
Section of Dermatology, Hospital Universitario Reina Sofía, Córdoba, Spain. md1mogij@uco.es
Moreno
J
J
D000293:Adolescent; D017353:Gene Deletion; D006801:Humans; D016114:Ichthyosis, X-Linked / Q000150:complications* / Q000235:genetics; D008297:Male; D009679:Nuclear Family; D010641:Phenotype; D011045:Poland Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods