[The coexistence of breast and ovarian cancer in patient with insertion-duplication of 12bp in BRCA1 gene].
In the paper we present the case of 39-year old patient admitted to the hospital because of double cancer (i.e. breast and ovarian cancer). This coexistence made us to check with PCR the possible irregularity in BCRA1 gene structure. The result of the study was the finding of insertion-duplication 12 bp in BRCA1 gene.
Zubelewicz-Szkodzińska
B
B
V Katedry i Kliniki Chorób Wewnetrzynch Slaskiej Akademii Medycznej w Katowicach.
Braczkowski
R
R
D000328:Adult; D001943:Breast Neoplasms / Q000150:complications* / Q000235:genetics*; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002881:Chromosomes, Human, Pair 12 / Q000235:genetics*; D005260:Female; D020440:Gene Duplication; D019398:Genes, BRCA1 / Q000235:genetics*; D006801:Humans; D016254:Mutagenesis, Insertional / Q000235:genetics; D010051:Ovarian Neoplasms / Q000150:complications* / Q000235:genetics*; D010375:Pedigree