title: Women with eating disorder tendencies display altered cardiovascular, neuroendocrine, and psychosocial profiles.
abstract: OBJECTIVE
  Cardiovascular, neuroendocrine, and psychosocial profiles were investigated in women with eating disorder tendencies, but who had never met clinical criteria for an eating disorder, and in healthy controls.
  
  
  METHODS
  Twenty-six women who scored in the highest distribution of the Eating Disorder Inventory bulimia subscale (HEDI women) and 27 women who scored in the lowest distribution (LEDI women) completed psychosocial questionnaires, underwent a speech reactivity task for measures of blood pressure and heart rate reactivity, and also underwent 24-hour ambulatory blood pressure monitoring and urinary neuroendocrine collection.
  
  
  RESULTS
  The HEDI women exhibited increased blood pressure and heart rate reactivity to the speech task and increased 24-hour urinary cortisol, but decreased 24-hour urinary norepinephrine compared with LEDI women. There were no overall group differences in 24-hour ambulatory blood pressure levels, but negative mood and tension were associated with greater systolic blood pressures for all women. Finally, HEDI women reported greater depressive symptoms and anxiety, lower self-esteem and sense of mastery, less social support, poor coping skills, and greater emotional impact of daily stressors relative to LEDI women.
  
  
  CONCLUSIONS
  These results indicate that the same pattern of neuroendocrine and psychosocial profiles seen in prior studies of bulimia nervosa are also present in women with eating disorder tendencies.
authors.affiliation: Department of Psychology, University of North Carolina at Chapel Hill, 27599-7175, USA.
authors.forename: J H
authors.initials: JH
authors.lastname: Koo-Loeb
authors.forename: N
authors.initials: N
authors.lastname: Costello
authors.forename: K C
authors.initials: KC
authors.lastname: Light
authors.forename: S S
authors.initials: SS
authors.lastname: Girdler
mesh_terms: D000293:Adolescent; D000328:Adult; D001143:Arousal / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D002032:Bulimia / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D004837:Epinephrine / Q000652:urine*; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology; D009638:Norepinephrine / Q000652:urine*; D010555:Personality Inventory; D010913:Pituitary-Adrenal System / Q000503:physiopathology; D012016:Reference Values; D013315:Stress, Psychological / Q000150:complications
chemical_list: D006854:Hydrocortisone; D009638:Norepinephrine; D004837:Epinephrine