Dietary conjugated linoleic acids alter adipose tissue and milk lipids of pregnant and lactating sows.
Conjugated linoleic acids (CLA) have been shown to affect fatty acid synthesis in various tissues. The objective of the study was to compare the effect of a commercial source of CLA with a linoleic acid-enriched oil (LA), supplied to 12 multiparous sows during gestation and lactation, on adipose tissue and milk fatty acid composition. The CLA isomers detected in the CLA oil were (in order of magnitude) c9,t11; t10,c12; c9,c11; t9,t11/t10,t12 and c10,c12 and amounted to 58.9 g/100 g fat. Biopsies were taken from the backfat on d 7 and 97 of gestation and milk samples were collected on d 2, 9, 16 and 23 after farrowing. Collection of colostrum and mature milk samples took place at 1100 h for sows who farrowed in the morning or at 1500 h for those who farrowed in the afternoon. All major CLA isomers in the supplement were transferred to the tissue and milk fat and, compared with the LA group, significantly increased saturated fatty acid and decreased monounsaturated fatty acid levels in the tissue and milk. These findings suggest a distinct involvement of CLA in the de novo fatty acid synthesis and desaturation process in the adipose tissue and mammary gland. Estimated transfer efficiency of dietary CLA isomers was 41-52% for the backfat and 55-69% for the mature milk. The incorporation and uptake efficiency seemed to be selective with the highest values found for c9,t11-CLA. Overall, dietary CLA supplementation of sows during gestation and lactation markedly altered backfat and milk fatty acid composition.
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Swiss Federal Station for Animal Production, Posieux, 1725 Switzerland.
D000273:Adipose Tissue / Q000187:drug effects*; D000818:Animals; D001724:Birth Weight / Q000187:drug effects; D003126:Colostrum / Q000737:chemistry; D004041:Dietary Fats / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D007774:Lactation / Q000378:metabolism*; D008041:Linoleic Acids / Q000008:administration & dosage / Q000494:pharmacology*; D008055:Lipids / Q000032:analysis*; D008892:Milk / Q000737:chemistry*; D011247:Pregnancy; D013237:Stereoisomerism; D013552:Swine
D004041:Dietary Fats; D008041:Linoleic Acids; D008055:Lipids