title: 3,5-Disubstituted-4-hydroxyphenyls linked to 3-hydroxy-2-methyl-4(1H)-pyridinone: potent inhibitors of lipid peroxidation and cell toxicity.
authors.affiliation: Department of Chemistry, Cerebrus, Winnersh, Wokingham, UK. david_bebbington@vpharm.com
authors.forename: D
authors.initials: D
authors.lastname: Bebbington
authors.forename: N J
authors.initials: NJ
authors.lastname: Monck
authors.forename: S
authors.initials: S
authors.lastname: Gaur
authors.forename: A M
authors.initials: AM
authors.lastname: Palmer
authors.forename: K
authors.initials: K
authors.lastname: Benwell
authors.forename: V
authors.initials: V
authors.lastname: Harvey
authors.forename: C S
authors.initials: CS
authors.lastname: Malcolm
authors.forename: R H
authors.initials: RH
authors.lastname: Porter
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001921:Brain / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D004353:Drug Evaluation, Preclinical; D016166:Free Radical Scavengers / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D066298:In Vitro Techniques; D007461:Iodoacetates; D015227:Lipid Peroxidation / Q000187:drug effects*; D018696:Neuroprotective Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D018384:Oxidative Stress / Q000187:drug effects*; D011728:Pyridones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D051381:Rats; D013329:Structure-Activity Relationship
chemical_list: D000975:Antioxidants; D016166:Free Radical Scavengers; D007461:Iodoacetates; D018696:Neuroprotective Agents; D011728:Pyridones; C412727:CEB 1370