Assessing the status of intrauterine insemination before forming a medically assisted conception unit.
A survey in 1996 of our female patients suggest that the three commonest causes of infertility were endometriosis, anovulation and idiopathic which comprises of about 70% of all the patients. In the male patients, sperm morphology evaluation by critical criteria showed that abnormal morphology was present in 71% while 87% of all the semen analysis were abnormal. The objective of this study was to assess the status of IUI before proceeding to formulate patient protocols for IVF in a tertiary infertility referral unit. A retrospective study of patients data was done from Jan 1995 to Dec 1996. Ovarian stimulation by clomiphene for anovulatory and idiopathic patients was performed on couples with at least one patent fallopian tube. Ovulation induction was by an intramuscular injection of 5000 i.u of HCG after follicular maturation. IUI was performed approximately 36-40 hours later. A total of 74 couples received 114 treatment cycles producing a total of 9 conceptions. The conception rate of IUI was therefore 7.89% per cycle and 12.16% per couple with the cumulative pregnancy rate of 28.21%. Associated success features of IUI found in this study were the age of the woman and the semen parameters of the husband.
Omar
M H
MH
Department of Obstetrics & Gynaecology, Universiti Kebangsaan Malaysia, Jalan Tenteram, Cheras, Kuala Lumpur.
Ong
F B
FB
Adeeb
N N
NN
Sharif
J M
JM
Nasri
N
N
Yassin
M J
MJ
D000858:Anovulation / Q000188:drug therapy; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D002996:Clomiphene / Q000627:therapeutic use; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use; D006801:Humans; D007317:Insemination, Artificial, Homologous; D008296:Malaysia; D008297:Male; D010053:Ovary / Q000187:drug effects; D010062:Ovulation Induction / Q000379:methods; D011247:Pregnancy; D018873:Pregnancy Rate
D006063:Chorionic Gonadotropin; D005300:Fertility Agents, Female; D002996:Clomiphene