title: Neurosteroid analogues. 8. Structure-activity studies of N-acylated 17a-aza-D-homosteroid analogues of the anesthetic steroids (3alpha, 5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
authors.affiliation: Departments of Molecular Biology and Pharmacology, Anesthesiology, Psychiatry, and Anatomy and Neurobiology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, Missouri 63110, USA.
authors.forename: D F
authors.initials: DF
authors.lastname: Covey
authors.forename: M
authors.initials: M
authors.lastname: Han
authors.forename: A S
authors.initials: AS
authors.lastname: Kumar
authors.forename: M A
authors.initials: MA
authors.lastname: de La Cruz
authors.forename: E S
authors.initials: ES
authors.lastname: Meadows
authors.forename: Y
authors.initials: Y
authors.lastname: Hu
authors.forename: A
authors.initials: A
authors.lastname: Tonnies
authors.forename: D
authors.initials: D
authors.lastname: Nathan
authors.forename: M
authors.initials: M
authors.lastname: Coleman
authors.forename: A
authors.initials: A
authors.lastname: Benz
authors.forename: A S
authors.initials: AS
authors.lastname: Evers
authors.forename: C F
authors.initials: CF
authors.lastname: Zorumski
authors.forename: S
authors.initials: S
authors.lastname: Mennerick
mesh_terms: D000777:Anesthetics / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism; D000818:Animals; D001667:Binding, Competitive; D001921:Brain / Q000378:metabolism; D018360:Crystallography, X-Ray; D004594:Electrophysiology; D006718:Homosteroids / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism; D066298:In Vitro Techniques; D008968:Molecular Conformation; D009865:Oocytes; D011278:Pregnanes / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism; D051381:Rats; D011963:Receptors, GABA-A / Q000378:metabolism / Q000502:physiology; D013329:Structure-Activity Relationship; D014982:Xenopus laevis
chemical_list: D000777:Anesthetics; D006718:Homosteroids; D011278:Pregnanes; D011963:Receptors, GABA-A