title: [Importance of blood tests for the diagnosis of drug allergies].
abstract: This work is devoted to the study of 22 dossiers of persons who have presented with clinical signs following taking a drug. The study was confined to patients in whom the symptoms had as origin a hypersensitivity (true or non-specific by histamine release). This study has allowed analysis of the value of several serological tests (measurement of leukotrienes, activation of basophils and T specific lymphocytes) in diagnosis and so to define the path to take that is best adapted to each case. The conclusion presents an agreement between the suspected diagnosis, after allergy enquiry and prick-tests, and the results of serological tests.
authors.affiliation: CHU, Tours.
authors.forename: A
authors.initials: A
authors.lastname: Venière
authors.forename: R
authors.initials: R
authors.lastname: Brousse
authors.forename: I
authors.initials: I
authors.lastname: Menelet
authors.forename: H
authors.initials: H
authors.lastname: Ait-Tamar
authors.forename: J
authors.initials: J
authors.lastname: Sainte-Laudy
authors.forename: A
authors.initials: A
authors.lastname: Sonneville
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015549:Basophil Degranulation Test; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D003875:Drug Eruptions / Q000097:blood / Q000175:diagnosis*; D005069:Evaluation Studies as Topic; D005260:Female; D006636:Histamine Release / Q000187:drug effects; D006801:Humans; D017997:Leukotriene C4 / Q000097:blood* / Q000378:metabolism; D008213:Lymphocyte Activation / Q000187:drug effects*; D008297:Male; D008875:Middle Aged
chemical_list: D017997:Leukotriene C4