title: Adjuvant chemotherapy for colorectal cancer: a Malaysian experience.
abstract: This study aims to evaluate the practice of adjuvant chemotherapy in colorectal cancer at the Institute of Radiotherapy and Oncology, Hospital Kuala Lumpur. A retrospective analysis of 320 patients' records from 1986 to 1994 was carried out. Adjuvant chemotherapy was given to 98 patients. Cancers of the rectum and sigmoid colon constituted over 60% of the patients. All the regimes used were 5-fluorouracil-based. The oral route was the most commonly used (55.1%). Toxicity was seldom the reason for stopping treatment (2%). The adjuvant treatment employed has been tolerable while the survival was comparable with other centres.
authors.affiliation: Institute of Radiotherapy and Oncology, Hospital Kuala Lumpur.
authors.forename: G C
authors.initials: GC
authors.lastname: Lim
authors.forename: K G
authors.initials: KG
authors.lastname: Rampal
authors.forename: I
authors.initials: I
authors.lastname: Fuad
authors.forename: A K
authors.initials: AK
authors.lastname: Lim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D017024:Chemotherapy, Adjuvant / Q000009:adverse effects; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000401:mortality; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D005472:Fluorouracil