Nickel-catalyzed electrochemical couplings of vinyl halides: synthetic and stereochemical aspects
Homo- and cross-coupling involving alkenyl halides have been performed efficiently using an electroassisted nickel-complex catalysis. Valuable product such as conjugated dienes, beta,gamma- or gamma,delta-unsaturated esters, ketones, or nitriles, as well as alkenylated aryl compounds are thus prepared with high yields and high stereoselectivity. Partial isomerization is only observed in a few cases, when the alkenyl halide is involved in a late step of the catalytic cycle. This is the case in the preparation of (Z,Z)-1,3-diene.
Cannes
C
Laboratoire d'Electrochimie, Catalyse et Synthese Organique, UMR 7582 CNRS-Universite Paris 12, Thiais, France.
Condon
S
Durandetti
M
Perichon
J
Nedelec
JY