title: Response time prolongation for a motion stimulus in patients with glaucoma and its relationship with elevation of the motion threshold.
abstract: OBJECTIVE
  To investigate whether response times for a motion stimulus are prolonged in glaucoma and to investigate the relationship between response time prolongation and motion threshold elevation in glaucoma.
  
  
  METHODS
  Motion displacement thresholds and response times were measured in 15 patients with glaucoma and 18 age-matched control subjects.
  
  
  RESULTS
  Mean test response times were significantly prolonged in the glaucomatous eyes than in the control eyes, with a mean delay of 200 milliseconds. After correcting for threshold elevation, response times at the motion threshold showed no significant difference between the groups.
  
  
  CONCLUSIONS
  Response times for motion detection are significantly prolonged in glaucoma and are accounted for by the threshold elevation in patients with glaucoma. The implications of these results are discussed in terms of the use of response time analysis to determine subject reliability.
authors.affiliation: Institute of Ophthalmology and Moorfields Eye Hospital, London, United Kingdom.
authors.forename: M C
authors.initials: MC
authors.lastname: Westcott
authors.forename: F W
authors.initials: FW
authors.lastname: Fitzke
authors.forename: A C
authors.initials: AC
authors.lastname: Viswanathan
authors.forename: R A
authors.initials: RA
authors.lastname: Hitchings
mesh_terms: D000328:Adult; D000368:Aged; D005902:Glaucoma, Open-Angle / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D009039:Motion Perception / Q000502:physiology*; D010775:Photic Stimulation; D011446:Prospective Studies; D011594:Psychometrics / Q000379:methods; D011930:Reaction Time / Q000502:physiology*; D012684:Sensory Thresholds / Q000502:physiology; D058609:Visual Field Tests; D014794:Visual Fields