title: Toxin-mediated haemolytic uraemic syndrome without diarrhoea.
abstract: A 52-year-old previously healthy man was admitted to the hospital with haematuria, painful micturition and fever. Laboratory investigation showed the presence of a haemolytic uraemic syndrome (HUS), characterized by haemolysis, renal insufficiency and mental disturbances. A urinary tract infection caused by a verotoxin-producing E. coli other than O157:H7 was diagnosed. Treatment of this infection resulted in his complete recovery from the illness. Both the search for a focus outside the gastrointestinal tract and the search for verotoxin genes by specific polymerase chain reaction can be crucial in a patient with HUS without preceding diarrhoea.
authors.affiliation: Departments of Internal Medicine, Haematology and Medical Microbiology, Academic Medical Centre, Amsterdam, The Netherlands. APhkater@yahoo.com
authors.forename: A P
authors.initials: AP
authors.lastname: Kater
authors.forename: A M
authors.initials: AM
authors.lastname: Westermann
authors.forename: M R
authors.initials: MR
authors.lastname: de Groot
authors.forename: A E
authors.initials: AE
authors.lastname: von dem Borne
authors.forename: E J
authors.initials: EJ
authors.lastname: Kuijper
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D004926:Escherichia coli / Q000145:classification / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000175:diagnosis*; D006463:Hemolytic-Uremic Syndrome / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin