title: Syndrome of inappropriate antidiuretic hormone secretion (SIADH) associated with prostatic carcinoma.
abstract: Inappropriate antidiuretic hormone secretion (SIADH) may occur in a variety of diseases, including malignancies, and can be induced by drugs. We report a case of SIADH associated with prostatic carcinoma. A 50-year-old man was admitted to hospital with severe flank pain and weight loss. The diagnosis of SIADH syndrome and prostatic carcinoma was established, and hormonal therapy was instituted. However, the patient died in a month without any response to therapy. We conclude that prostatic carcinoma may cause SIADH and should therefore be considered in the differential diagnosis.
authors.affiliation: Hacettepe University Institute of Oncology, Ankara, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Yalçin
authors.forename: M
authors.initials: M
authors.lastname: Erman
authors.forename: G
authors.initials: G
authors.lastname: Tekuzman
authors.forename: S
authors.initials: S
authors.lastname: Ruacan
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000726:Androgen Antagonists / Q000008:administration & dosage; D000813:Anilides / Q000008:administration & dosage; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002277:Carcinoma / Q000150:complications* / Q000188:drug therapy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D017273:Goserelin / Q000008:administration & dosage; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009570:Nitriles; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000209:etiology*; D011471:Prostatic Neoplasms / Q000150:complications* / Q000188:drug therapy; D014105:Tosyl Compounds; D015431:Weight Loss
chemical_list: D000726:Androgen Antagonists; D000813:Anilides; D018931:Antineoplastic Agents, Hormonal; D009570:Nitriles; D014105:Tosyl Compounds; D017273:Goserelin; C053541:bicalutamide