title: [A comprehensive study of the mechanisms of the development of chronic inflammation in periodontitis].
abstract: Bacteriological and cytological analysis of the saliva, dental plaques, and gingival fluid was carried out in 48 patients with periodontitis and 25 donors. The concentrations of proinflammatory cytokines IL-1 and TNF-alpha were increased, the levels of anti-inflammatory cytokines IL-4 and TFR beta-1 were decreased, and MIF production was suppressed in the patients in comparison with donors. Important theoretical and practical recommendations are offered.
authors.forename: T P
authors.initials: TP
authors.lastname: Ivaniushko
authors.forename: L V
authors.initials: LV
authors.lastname: Gankovskaia
authors.forename: L V
authors.initials: LV
authors.lastname: Koval'chuk
authors.forename: G P
authors.initials: GP
authors.lastname: Ter-Asaturov
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Kassin
authors.forename: E V
authors.initials: EV
authors.lastname: Budanova
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003773:Dental Plaque / Q000382:microbiology; D005883:Gingival Crevicular Fluid / Q000737:chemistry / Q000166:cytology / Q000382:microbiology; D006801:Humans; D007124:Immunoenzyme Techniques; D018836:Inflammation Mediators / Q000032:analysis; D008875:Middle Aged; D010518:Periodontitis / Q000209:etiology* / Q000382:microbiology; D012016:Reference Values; D012463:Saliva / Q000737:chemistry / Q000166:cytology / Q000382:microbiology
chemical_list: D018836:Inflammation Mediators