title: Maternal and neonatal outcome in early- and late-onset pre-eclampsia.
abstract: Early-onset pre-eclampsia and late-onset pre-eclampsia, by virtue of their unpredictable nature and prediliction for multi-organ involvement, are associated with substantial maternal and fetal morbidity and mortality. Recent years have seen the introduction of the concepts of care in specialized units, expectant management of pre-eclampsia, conservative management of the HELLP syndrome (haemolysis, elevated liver enzymes, low platelets), usage of magnesium sulphate and improved feto-maternal surveillance. It is important to note that these factors also influence maternal and neonatal outcome.
authors.affiliation: Department of Obstetrics and Gynaecology and MRC/UN Pregnancy Hypertension Research Unit, University of Natal Medical School, Durban, South Africa.
authors.forename: F
authors.initials: F
authors.lastname: Paruk
authors.forename: J
authors.initials: J
authors.lastname: Moodley
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D004461:Eclampsia / Q000209:etiology; D005260:Female; D017359:HELLP Syndrome / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology; D008278:Magnesium Sulfate / Q000008:administration & dosage / Q000627:therapeutic use*; D011225:Pre-Eclampsia / Q000145:classification / Q000628:therapy*; D011247:Pregnancy; D012008:Recurrence; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology; D012307:Risk Factors; D016019:Survival Analysis; D013997:Time Factors
chemical_list: D000959:Antihypertensive Agents; D008278:Magnesium Sulfate