title: Inhibitory effects of plant polyphenoloxidase on colonization factors of Streptococcus sobrinus 6715.
abstract: Exogenously added polyphenoloxidase (EC 1.14.18.1), an enzyme which oxidizes tyrosine residues and is commonly found in many dietary components, abolished the aggregation of Streptococcus sobrinus 6715 by high-molecular-weight dextran. The enzyme decreased glucan-binding lectin and/or glucosyltransferase I activities.
authors.affiliation: Department of Microbiology, Miami University, Oxford, Ohio 45056, USA. cowanmm@muohio.edu
authors.forename: M M
authors.initials: MM
authors.lastname: Cowan
authors.forename: E A
authors.initials: EA
authors.lastname: Horst
authors.forename: S
authors.initials: S
authors.lastname: Luengpailin
authors.forename: R J
authors.initials: RJ
authors.lastname: Doyle
mesh_terms: D001422:Bacterial Adhesion / Q000187:drug effects; D001426:Bacterial Proteins; D004156:Catechol Oxidase / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D015169:Colony Count, Microbial; D003911:Dextrans / Q000494:pharmacology; D005936:Glucans / Q000378:metabolism; D005964:Glucosyltransferases; D006801:Humans; D037102:Lectins / Q000378:metabolism; D037121:Plant Lectins; D010944:Plants / Q000737:chemistry* / Q000201:enzymology; D011506:Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D016986:Streptococcus sobrinus / Q000187:drug effects* / Q000502:physiology
chemical_list: D001426:Bacterial Proteins; D003911:Dextrans; D005936:Glucans; D037102:Lectins; D037121:Plant Lectins; D011506:Proteins; C067118:GTF-I protein, Streptococcus; D004156:Catechol Oxidase; D005964:Glucosyltransferases; C489364:glucosyltransferase I