title: Tracheal intubating conditions after induction with sevoflurane 8% in children. A comparison with two intravenous techniques.
abstract: We studied tracheal intubating conditions in 120 healthy children, aged 3-12 years, in a blinded, randomised clinical trial. Children were randomly allocated to one of three groups: group PS, propofol 3 mg.kg-1 and succinylcholine 1 mg.kg-1 (n = 40); group PA, propofol 3 mg.kg-1 and alfentanil 10 microg.kg-1 (n = 40); group SF, sevoflurane 8% in 60% nitrous oxide in oxygen for 3 min (n = 40). Tracheal intubating conditions were graded according to ease of laryngoscopy, position of vocal cords, coughing, jaw relaxation and movement of limbs. Overall intubating conditions were acceptable in 39 of 40 children in the propofol/succinylcholine group, 21 of 40 children in the propofol/alfentanil group and 35 of 40 children in the sevoflurane group. Children receiving propofol and succinylcholine or sevoflurane had better intubating conditions overall than those given propofol and alfentanil (p < 0.01). In conclusion, anaesthetic induction and tracheal intubation using sevoflurane 8% for 3 min is a satisfactory alternative to propofol with succinylcholine in children.
authors.affiliation: The Ulster Hospital, Dundonald, Belfast, UK.
authors.forename: J M
authors.initials: JM
authors.lastname: Blair
authors.forename: D A
authors.initials: DA
authors.lastname: Hill
authors.forename: I M
authors.initials: IM
authors.lastname: Bali
authors.forename: J P
authors.initials: JP
authors.lastname: Fee
mesh_terms: D015760:Alfentanil / Q000494:pharmacology*; D000701:Analgesics, Opioid / Q000494:pharmacology*; D000777:Anesthetics / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal / Q000379:methods*; D007828:Laryngoscopy / Q000379:methods; D008297:Male; D008738:Methyl Ethers / Q000494:pharmacology*; D009467:Neuromuscular Depolarizing Agents / Q000494:pharmacology; D015742:Propofol / Q000494:pharmacology*; D000077149:Sevoflurane; D013390:Succinylcholine / Q000494:pharmacology*
chemical_list: D000701:Analgesics, Opioid; D000777:Anesthetics; D008738:Methyl Ethers; D009467:Neuromuscular Depolarizing Agents; D015760:Alfentanil; D000077149:Sevoflurane; D013390:Succinylcholine; D015742:Propofol