title: Paraparesis after lumbar puncture in a male with leukemia.
abstract: A diagnostic lumbar puncture was performed in a 12-year-old male with acute lymphoblastic leukemia. Because of thrombocytopenia (platelet count 42,000/mm(3)), a platelet transfusion was given immediately before the lumbar puncture. However, the platelet count was not re-examined. The patient developed progressive paraparesis shortly after the lumbar puncture. Magnetic resonance imaging revealed an extensive spinal subdural hematoma from the T2 to S2 level. This case report illustrates the sometimes dramatic consequences of lumbar puncture in patients with childhood leukemia. Guidelines for the examination of the platelet count and correction of thrombocytopenia before lumbar puncture are discussed.
authors.affiliation: Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: P W
authors.initials: PW
authors.lastname: Wirtz
authors.forename: B R
authors.initials: BR
authors.lastname: Bloem
authors.forename: F J
authors.initials: FJ
authors.lastname: van der Meer
authors.forename: O F
authors.initials: OF
authors.lastname: Brouwer
mesh_terms: D002648:Child; D020199:Hematoma, Subdural, Acute / Q000150:complications / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D020335:Paraparesis / Q000209:etiology*; D010976:Platelet Count; D017713:Platelet Transfusion; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000175:diagnosis; D013129:Spinal Puncture / Q000009:adverse effects*; D013921:Thrombocytopenia / Q000150:complications* / Q000209:etiology / Q000628:therapy