title: Fungal keratitis in a soft contact lens wearer.
abstract: OBJECTIVE
  To describe a case of fungal keratitis in a soft contact lens wearer.
  
  
  RESULTS
  A 57 year old female, compliant, frequent replacement soft contact lens wearer, with a possible prior history of herpes simplex keratitis, presented with pain and injection of her left eye of four weeks duration. Gram stain of a corneal ulcer of the left eye revealed fungal organisms and cultures grew Fusarium solani. The infiltrate responded to topical and systemic antifungal agents, but a corneal perforation developed which required a therapeutic penetrating keratoplasty.
  
  
  CONCLUSIONS
  Fungal infections are a cause of corneal ulcers in contact lens wearers. Despite the use of topical and systemic antifungal agents, fungal ulcers frequently require surgical intervention.
authors.affiliation: Cornea Service, Wills Eye Hospital, Philadelphia, PA 19107, USA.
authors.forename: R
authors.initials: R
authors.lastname: Foroozan
authors.forename: R C
authors.initials: RC
authors.lastname: Eagle
authors.forename: E J
authors.initials: EJ
authors.lastname: Cohen
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects* / Q000382:microbiology; D003315:Cornea / Q000382:microbiology / Q000473:pathology; D003320:Corneal Ulcer / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D003937:Diagnosis, Differential; D015821:Eye Infections, Fungal / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D005260:Female; D005670:Fusarium / Q000302:isolation & purification*; D006801:Humans; D015948:Keratoplasty, Penetrating; D008875:Middle Aged; D009181:Mycoses / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D009883:Ophthalmic Solutions; D012422:Rupture, Spontaneous; D014792:Visual Acuity
chemical_list: D000935:Antifungal Agents; D009883:Ophthalmic Solutions