Stevens-Johnson syndrome after erythromycin therapy while deployed at sea.
Stevens-Johnson syndrome is a cutaneous reaction pattern that represents the progression of symptoms of erythema multiforme. These reactions can range from mild (EM minor) to severe (EM major) and even life-threatening (Stevens-Johnson syndrome or toxic epidermal necrolysis). The difference between Stevens-Johnson syndrome and toxic epidermal necrolysis is the percentage of body surface area involved; toxic epidermal necrolysis involves widespread skin necrosis and bullous formation with epidermal detachment resembling scalded skin. The three most common triggers for Stevens-Johnson syndrome are herpes simplex infection, Mycoplasma infection, and drug reactions. This is a case of Stevens-Johnson syndrome occurring after erythromycin treatment aboard an aircraft carrier while deployed at sea in the Persian Gulf.
Williams
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Naval Hospital Branch Medical Clinic, Naval Air Station, Jacksonville, FL 32214-5000, USA.
D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001830:Body Surface Area; D003937:Diagnosis, Differential; D004917:Erythromycin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008776:Methylprednisolone Hemisuccinate / Q000627:therapeutic use; D008889:Military Personnel; D009326:Naval Medicine; D012307:Risk Factors; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D014481:United States
D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D008776:Methylprednisolone Hemisuccinate; D004917:Erythromycin