title: Hemorrhagic shock and encephalopathy syndrome: neurologic features.
abstract: Hemorrhagic shock and encephalopathy syndrome (HSES) is a severe disease that affects previously healthy infants of less than 1 year of age and is associated with significant mortality and neurologic morbidity. It is characterized by sudden onset of shock, convulsions and coma, bleeding due to severe coagulopathy, fever, diarrhea, metabolic acidosis, and hepatorenal dysfunction. Central nervous system involvement with recurrent seizures and brain edema is the most common cause of high mortality and neurological morbidity. In this report, we describe four patients of HSES and review the initial and follow-up neurological features, electroencephalography findings, and the results of neuroradiological examinations of this catastrophic illness.
authors.affiliation: Ankara University Faculty of Medicine, Department of Paediatric, Turkey. ince@dialup.ankara.edu.tr
authors.forename: E
authors.initials: E
authors.lastname: Ince
authors.forename: Z
authors.initials: Z
authors.lastname: Kuloglu
authors.forename: Z
authors.initials: Z
authors.lastname: Akinci
mesh_terms: D001927:Brain Diseases / Q000150:complications; D017809:Fatal Outcome; D005260:Female; D005334:Fever / Q000150:complications; D006801:Humans; D007223:Infant; D008297:Male; D012640:Seizures / Q000209:etiology; D012771:Shock, Hemorrhagic / Q000150:complications; D013577:Syndrome