Hepatic arterial chemotherapy for colorectal cancer metastatic to the liver.
In advanced colorectal cancer, liver metastases are a major problem. In patients with liver metastases as the major site of disease hepatic arterial chemotherapy is a valid alternative to systemic treatment. In this review about hepatic arterial chemotherapy we will discuss the theoretical and practical aspects, the results and complications, the selection of patients for hepatic arterial chemotherapy, and its future developments.
van Riel
J M
JM
Department of Medical Oncology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands. jmgh.vriel@azvu.nl
van Groeningen
C J
CJ
Giaccone
G
G
Pinedo
H M
HM
D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005467:Floxuridine / Q000008:administration & dosage / Q000627:therapeutic use; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000009:adverse effects; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D018579:Patient Selection
D000964:Antimetabolites, Antineoplastic; D005467:Floxuridine; D005472:Fluorouracil