Abnormal microcirculation and temperature in skin above tender points in patients with fibromyalgia.
OBJECTIVE
Skin temperature and skin blood flow were studied above different tender points in 20 patients with fibromyalgia (FM) and 20 healthy controls.


METHODS
Blood flow was measured by laser Doppler flowmetry and skin temperature was measured with an infrared thermometer.


RESULTS
In the skin above the five tender points examined in each subject, we found an increased concentration of erythrocytes, decreased erythrocyte velocity and a consequent decrease in the flux of erythrocytes. A decrease in temperature was recorded above four of the five tender points.


CONCLUSIONS
Vasoconstriction occurs in the skin above tender points in FM patients, supporting the hypothesis that FM is related to local hypoxia in the skin above tender points.
Jeschonneck
M
M
Department of Internal Medicine IV and. Department of Internal Medicine III, Friedrich Schiller University, Jena, Germany.
Grohmann
G
G
Hein
G
G
Sprott
H
H
D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000502:physiology; D005260:Female; D005356:Fibromyalgia / Q000503:physiopathology*; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D012039:Regional Blood Flow; D012881:Skin Temperature