title: [Characteristics of epidemiological strains of influenza A virus (H3N2) isolate in 1997-1999. Virus A/Moscow/10/99--a candidate to become the vaccine strain].
abstract: Antigenic properties of influenza A(H3N2) viruses isolated during two epidemic seasons 1997-98 and 1998-99 in Russia are analyzed. All strains are antigenic variants of the reference strain A/Sydney/5/97. Characteristics of epidemic strain A/Moscow/10/99, proposed by WHO expert committee as vaccine strain for 1999-2000 have been studied. This strain, isolated on chick embryos, is characterized by high reproductive activity in chicken embryos with an infectious titer of 10(6) EID50/0.2 ml, easily adapts to MDCK culture, and has a thermostable hemagglutinin.
authors.forename: A N
authors.initials: AN
authors.lastname: Slepushkin
authors.forename: V T
authors.initials: VT
authors.lastname: Ivanova
authors.forename: E I
authors.initials: EI
authors.lastname: Burtseva
authors.forename: T A
authors.initials: TA
authors.lastname: Oskerko
authors.forename: T N
authors.initials: TN
authors.lastname: Volodina
authors.forename: S G
authors.initials: SG
authors.lastname: Kuribko
authors.forename: L V
authors.initials: LV
authors.lastname: Kolobukhina
authors.forename: M V
authors.initials: MV
authors.lastname: Beda
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000276:immunology; D002642:Chick Embryo; D004196:Disease Outbreaks; D006801:Humans; D053122:Influenza A Virus, H3N2 Subtype; D009980:Influenza A virus / Q000276:immunology / Q000302:isolation & purification*; D007252:Influenza Vaccines / Q000276:immunology*; D007251:Influenza, Human / Q000453:epidemiology / Q000517:prevention & control / Q000821:virology*; D009031:Moscow / Q000453:epidemiology
chemical_list: D000956:Antigens, Viral; D007252:Influenza Vaccines