The biology of inherited cancer.
This issue of Cancer Biology is focused on inherited cancer. In this short introduction to the topic we give a brief overview and list genes and the corresponding inherited cancer syndromes. We discuss the basic mechanisms of inherited cancer and the clinical implication of predictive genetic testing for cancer.
Lindblom
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Department of Molecular Medicine, Karolinska Institutet, Stockholm, SE-171 76, Sweden.
Nordenskjöld
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D004198:Disease Susceptibility; D005820:Genetic Testing; D006801:Humans; D009369:Neoplasms / Q000235:genetics*; D009386:Neoplastic Syndromes, Hereditary / Q000235:genetics*; D010375:Pedigree; D012307:Risk Factors