Identification and characteristics of a novel Burkholderia strain with broad-spectrum antimicrobial activity.
A Burkholderia strain isolated from soil is capable of inhibiting the growth of bacteria, plant-pathogenic fungi, pathogenic yeasts, and protozoa. Inhibition does not involve cell contact or the presence of living cells, suggesting that at least a substantial portion of the antimicrobial activity is due to the excretion of extracellular compounds.
Cain
C C
CC
Fralin Biotechnology Center, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061-0346, USA.
Henry
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AT
Waldo
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RH
Casida
L J
LJ
Falkinham
J O
JO
D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000378:metabolism / Q000494:pharmacology*; D000898:Antibiosis; D001419:Bacteria / Q000187:drug effects / Q000254:growth & development*; D019117:Burkholderia / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification / Q000502:physiology*; D056890:Eukaryota / Q000187:drug effects / Q000254:growth & development*; D005658:Fungi / Q000187:drug effects / Q000254:growth & development*; D008826:Microbial Sensitivity Tests; D010935:Plant Diseases / Q000382:microbiology; D012988:Soil Microbiology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents