[The efficacy of the substitution of carnivit in patients with chronic failure treated with hemodialysis].
Low serum concentration of the carnitine is one of the causes of muscle weakness and cardiomyopathy in patients with chronic renal failure treated by hemodialysis. The carnitine facilitate transport of the free fatty acid into the straitened muscle cells where the product of oxidation is energy-ATP. In the present paper we presented the investigation of the influence of L-carnitine substitution on cardiac performance. The results indicate the positive influence of this treatment on metabolic and haemodynamic cardiac parameters. The subjective patients opinion of L-carnitine treatment was also positive.
Wanic-Kossowska
M
M
Klinika Nefrologii Instytutu Chorób Wewnetrznych, Akademii Medycznej, K. Marcinkowskiego w Poznaniu.
Piszczek
I
I
Rogacka
D
D
Czarnecki
R
R
Kozioł
L
L
Czekalski
S
S
D000328:Adult; D000368:Aged; D002331:Carnitine / Q000097:blood / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods*
D002331:Carnitine