title: Inherited epithelial tumors of the kidney: old and new diseases.
abstract: This review summarizes information on inherited epithelial tumors of the kidney. Emphasis is placed on identifying clinically distinct inherited forms of renal cancer because each distinct clinical syndrome defines a different renal cancer susceptibility gene. So far, two genes that predispose to epithelial cancers of the kidney have been identified, VHL and the MET proto-oncogene. Available evidence suggests that several renal cancer genes remain to be identified.
authors.affiliation: Laboratory of Immunobiology, Divison of Basic Sciences, National Cancer Institute-Frederick Cancer Research Facility, Frederick, MD 21702, USA.
authors.forename: B
authors.initials: B
authors.lastname: Zbar
mesh_terms: D002893:Chromosomes, Human, Pair 3 / Q000235:genetics; D004198:Disease Susceptibility; D006801:Humans; D007680:Kidney Neoplasms / Q000235:genetics* / Q000378:metabolism; D000090063:Proto-Oncogene Mas; D014178:Translocation, Genetic; D006623:von Hippel-Lindau Disease / Q000145:classification / Q000235:genetics / Q000378:metabolism