Squamous cell carcinoma arising in transplanted skin.
Squamous cell carcinoma arising in a skin graft is rare. Previous reports concern the use of skin in heterotopic locations namely the vagina and oral cavity. We report a case of squamous cell carcinoma, which arose in a skin graft used for resurfacing a scalp defect. The defect followed the excision of a basal cell carcinoma 11 years previously. The excision was incomplete and radiotherapy had been given. The possible pathological mechanisms for the development of a squamous cell carcinoma in transplanted skin are discussed.
Kavouni
A
A
Department of Plastic and Reconstructive Surgery, Royal London Hospital, UK. aka@stfriday.freeserve.co.uk
Shibu
M
M
Carver
N
N
D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000532:radiotherapy / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D012535:Scalp / Q000473:pathology; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology; D016038:Skin Transplantation; D013524:Surgical Flaps / Q000473:pathology