title: [Outbreak of hemorrhagic fever with kidney syndrome in Egor'ev district of Moscow region].
abstract: Epizootological, serological, and molecular virological analysis of an outbreak of hemorrhagic fever with renal syndrome (HFRS) in the Egoryevsk district of Moscow region (September 1995-January 1996) has been carried out. Hantavirus (Puumala) antigen and virus-specific antibodies were isolated from bank voles captured in the endemic focus. Anti-Puumala antibodies were detected in the sera of all HFRS patients and in 2% healthy residents of the endemic focus. Analysis of nucleotide sequence (RNA from hantavirus-positive lung of a bank vole) showed that the studied hantavirus is a distinct genotype of Puumala virus. Hence, a new highly active natural focus of HFRS associated with Puumala virus, dangerous for the population, has been revealed in Moscow region.
authors.forename: A P
authors.initials: AP
authors.lastname: Ivanov
authors.forename: A E
authors.initials: AE
authors.lastname: Dekonenko
authors.forename: T K
authors.initials: TK
authors.lastname: Dzagurova
authors.forename: A E
authors.initials: AE
authors.lastname: Malkin
authors.forename: V I
authors.initials: VI
authors.lastname: Shervarli
authors.forename: P M
authors.initials: PM
authors.lastname: Baranovskiĭ
authors.forename: N V
authors.initials: NV
authors.lastname: Vardanian
authors.forename: V E
authors.initials: VE
authors.lastname: Bulanov
authors.forename: E I
authors.initials: EI
authors.lastname: Nikolaeva
authors.forename: E A
authors.initials: EA
authors.lastname: Tkachenko
mesh_terms: D000818:Animals; D004196:Disease Outbreaks; D004197:Disease Reservoirs; D018063:Hantaan virus; D006480:Hemorrhagic Fever with Renal Syndrome / Q000453:epidemiology*; D006801:Humans; D009031:Moscow / Q000453:epidemiology