title: Long-term mechanical stability of the impacted morselized graft-cement interface in total joint replacement: an experimental study in dogs.
abstract: This experimental study compared the long-term (12 months) mechanical stability of the morselized graft-cement interface with the conventional bone-cement interface in both femoral bones of 10 adult dogs. For mechanical testing, three-point bending and push-out loading tests of composite bone-cement beams were used, while the incorporation of the graft was assessed by serial radiographs. Although the parameters fracture load and interface failure load showed inferior values in the specimens with a morselized graft-cement interface compared to those in specimens with a conventional bone-cement interface, no statistically significant differences were found between groups. Radiographic reconstitution of the lateral femoral cortex was observed in all animals at 3 months while signs of advanced remodeling were apparent at 6 months. These results indicate the long-term mechanical stability of the impacted morselized graft-cement interface is comparable to that of the conventional bone-cement interface created in primary total hip replacements provided the grafted area is protected from early heavy loading.
authors.affiliation: Orthopedic Department, Athens University, KAT Hospital, Greece.
authors.forename: K G
authors.initials: KG
authors.lastname: Stamos
authors.forename: T
authors.initials: T
authors.lastname: Karachalios
authors.forename: P J
authors.initials: PJ
authors.lastname: Papagelopoulos
authors.forename: T
authors.initials: T
authors.lastname: Xenakis
authors.forename: D S
authors.initials: DS
authors.lastname: Korres
authors.forename: E
authors.initials: E
authors.lastname: Koroneos
authors.forename: G
authors.initials: G
authors.lastname: Hartofilakidis
mesh_terms: D000818:Animals; D019644:Arthroplasty, Replacement, Hip / Q000379:methods; D001696:Biomechanical Phenomena; D001843:Bone Cements; D016723:Bone Remodeling / Q000502:physiology; D004285:Dogs; D005269:Femur / Q000601:surgery*; D008297:Male; D008422:Materials Testing; D023421:Models, Animal; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D013314:Stress, Mechanical
chemical_list: D001843:Bone Cements