Controversies in sentinel lymph node biopsy for breast cancer.
Sentinel lymph node biopsy, validated in melanoma staging, is currently under investigation for breast cancer staging. Reports suggest that the sentinel lymph node has a high predictive value in determining the presence of axillary metastases. Identification of a sentinel lymph node that is free of metastatic tumor cells may eliminate the necessity of performing a standard axillary lymph node dissection with its attendant morbidity. Numerous techniques are utilized to identify the sentinel node with approximately the same success rate. This paper will address some of the controversial areas of sentinel lymph node biopsy and offer an option for physicians who want to develop a sentinel lymph node program in their hospital.
Jeffrey
S S
SS
Division of Surgical Oncology, Stanford University School of Medicine, California, USA. ssj@stanford.edu
Jones
S B
SB
Smith
K L
KL
D001943:Breast Neoplasms / Q000473:pathology*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D021701:Sentinel Lymph Node Biopsy