[Acute coronary syndrome associated with Chlamydia pneumoniae pneumonia in two cases].
Epidemiological and clinical studies attribute to Chlamydia pneumoniae infections a pathogenetic role in atherosclerotic vascular lesions. We report two patients in whom this infection was followed by acute coronary events. A 51 years old male presented with a right lower lobe pneumonia and a positive immunofluorescence serology for Chlamydia pneumoniae, with a IgM titer of 1/64. On the second day of evolution, he experienced an acute myocardial infarction. A coronary arteriography demonstrated a 80% obstruction of anterior coronary artery and an angioplasty was performed. A 84 years old male was admitted with a right lower lobe pneumonia and a positive serology for Chlamydia pneumoniae, with an IgM titer of 1/32. On the fourth day of evolution, he developed unstable angina with electrocardiographic changes. A coronary arteriography demonstrated a three vessel disease. In both cases, a tight chronological association was observed between Chlamydia pneumoniae infection and acute coronary events.
Parada
M T
MT
Departamento Broncopulmonar Clínica Avansalud, Clínica Las Condes, Santiago de Chile.
Kauffmann
R
R
D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood; D002690:Chlamydia Infections / Q000150:complications* / Q000175:diagnosis; D016993:Chlamydophila pneumoniae; D003327:Coronary Disease / Q000382:microbiology*; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000150:complications* / Q000175:diagnosis; D013577:Syndrome
D000907:Antibodies, Bacterial; D007075:Immunoglobulin M