Small subchronic doses of the pesticide dimethoate and/or cadmium and lead treatment causes disturbances in the chromosomes of young rats.
Small doses of Dimethoate (DM) and cadmium (Cd) which in themselves proved to be harmless in causing chromosome aberrations, potentiate each other's toxic effect concerning both numerical and structural aberrations caused in rat bone marrow cells. The toxic effect of lead (Pb) was not enhanced by DM.
Dési
I
I
Department of Public Health, Albert Szent-Györgyi University Medical School, Szeged, Hungary. des@puhe.szote.u-szeged.hu
Nehéz
M
M
Siroki
O
O
Nagymajtényi
L
L
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002104:Cadmium / Q000633:toxicity*; D002869:Chromosome Aberrations; D004117:Dimethoate / Q000008:administration & dosage / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D007854:Lead / Q000633:toxicity*; D008297:Male; D009153:Mutagens / Q000633:toxicity*; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar
D009153:Mutagens; D002104:Cadmium; D007854:Lead; D004117:Dimethoate