Gadolinium-based contrast: an alternative contrast agent for endovascular interventions.
The radiocontrast substance gadoterate meglumine (Gd-DOTA) is used in magnetic resonance imaging. Because of its low rate of adverse drug reactions, we evaluated Gd-DOTA as an alternative contrast medium in diagnostic and therapeutic procedures. Twenty-three consecutive procedures were performed using undiluted contrast agent Gd-DOTA (376.9 mg/mL, Dotarem) in digital subtraction techniques. A dosage of 30-90 mL was used. Serum creatinine levels were registered before and at 24 and 48 hr after the procedure. Based on this limited experience, Gd-DOTA may be used as an alternative contrast agent in selected endovascular procedures, when iodine is contraindicated.
Parodi
J C
JC
Instituto Cardiovascular de Buenos Aires, Argentina.
Ferreira
L M
LM
D000792:Angiography; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D006801:Humans; D008297:Male; D008536:Meglumine; D008875:Middle Aged; D009942:Organometallic Compounds; D011446:Prospective Studies; D014656:Vascular Surgical Procedures
D003287:Contrast Media; D009942:Organometallic Compounds; D008536:Meglumine; D005682:Gadolinium; C072417:gadoterate meglumine