Human developmental biology of granulocyte colony-stimulating factor.
The availability of granulocyte colony-stimulating factor (G-CSF) has influenced the management of neonates with neutropenia. Since the first use of G-CSF in a neonate with neutropenia, much has been learned about the cellular sources and physiologic roles of G-CSF. This article reviews our present understanding of G-CSF and its cognate receptor in the fetus and neonate.
Calhoun
D A
DA
Department of Pediatrics, University of Florida College of Medicine, Gainesville, USA. calhoda@peds.ufl.edu
Christensen
R D
RD
D000375:Aging / Q000502:physiology*; D002477:Cells / Q000378:metabolism; D016179:Granulocyte Colony-Stimulating Factor / Q000378:metabolism / Q000502:physiology* / Q000627:therapeutic use; D006801:Humans; D015931:Intensive Care, Neonatal; D016188:Receptors, Granulocyte Colony-Stimulating Factor / Q000378:metabolism; D014018:Tissue Distribution
D016188:Receptors, Granulocyte Colony-Stimulating Factor; D016179:Granulocyte Colony-Stimulating Factor