Absolute configuration at C45 in 45-hydroxyyessotoxin, a marine polyether toxin isolated from shellfish.
The marine polyether toxin, 45-hydroxyyessotoxin, was isolated together with yessotoxin from the scallop, Patinopecten yessoensis. The 45-hydroxy group in the side chain was esterified with (S)- and (R)-alpha-methoxyalpha-trifluoromethylphenylacetic acids (MTPA). A detailed analysis of the 2D NMR spectra of the two esters established the R configuration at C45.
Morohashi
A
A
Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Satake
M
M
Oshima
Y
Y
Yasumoto
T
T
D000818:Animals; D004988:Ethers, Cyclic / Q000737:chemistry*; D008956:Models, Chemical; D008974:Mollusca / Q000737:chemistry*; D008978:Mollusk Venoms / Q000302:isolation & purification*; D035964:Oxocins
C419348:45-hydroxyyessotoxin; D004988:Ethers, Cyclic; D008978:Mollusk Venoms; D035964:Oxocins; C066632:yessotoxin