title: New annonaceous acetogenins from the roots of Uvaria calamistrata.
abstract: Five new annonaceous acetogenins, calamistrins C-G (1-5), were isolated from an ethanolic extract of the roots of Uvaria calamistrata. Compounds 1-3 were mono-THF ring acetogenins; compounds 4 and 5 were bis-THF acetogenins, with the THF rings from C-18 to C-25. The absolute configurations of 3, 4, and 5 as well as the partial absolute configurations of 1 and 2 were determined by (13)C NMR spectroscopy and advanced Mosher methodology.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.
authors.forename: G X
authors.initials: GX
authors.lastname: Zhou
authors.forename: R Y
authors.initials: RY
authors.lastname: Chen
authors.forename: Y J
authors.initials: YJ
authors.lastname: Zhang
authors.forename: D Q
authors.initials: DQ
authors.lastname: Yu
mesh_terms: D004354:Drug Screening Assays, Antitumor; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D014407:Tumor Cells, Cultured
chemical_list: D005663:Furans; D007783:Lactones; C112079:isomurisolenin