Perspectives in three-dimensional analysis of bone samples using synchrotron radiation microtomography.
In this paper we present a methodology based on 3D synchrotron radiation microtomography to analyze non-destructively 3D bone samples. After a technical presentation of the imaging system and the image analysis techniques, we report results on three-dimensional analysis of vertebral samples from women of different ages. The new capabilities of this technique for the investigation of bone are discussed. They include a high spatial resolution down to the micron level, a high density resolution allowing a local quantification of bone mineralization, phase contrast imaging and advances in 3D image analysis.
Peyrin
F
F
CREATIS, 502, INSA, Villeurbanne, France. peyrin@creatis.insa-lyon.fr
Salomé
M
M
Nuzzo
S
S
Cloetens
P
P
Laval-Jeantet
A M
AM
Baruchel
J
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism / Q000473:pathology; D015519:Bone Density; D001842:Bone and Bones / Q000033:anatomy & histology* / Q000378:metabolism; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008858:Microscopy, Phase-Contrast / Q000295:instrumentation / Q000379:methods; D008875:Middle Aged; D017356:Synchrotrons / Q000295:instrumentation; D014054:Tomography / Q000295:instrumentation / Q000379:methods*