Pattern formation: a new twist to BMP signalling.
Dorsal-ventral patterning in Xenopus and Drosophila embryos involves BMP family signalling molecules. Twisted Gastrulation has now been added to the list of proteins that regulate the activity of these molecules, providing new insights into how BMPs are made available to their signalling receptors.
Dale
L
L
Department of Anatomy and Developmental Biology, University College London, Gower Street, WC1E 6BT, London, UK. l.dale@ucl.ac.uk
D000818:Animals; D019521:Body Patterning / Q000235:genetics; D019485:Bone Morphogenetic Proteins / Q000378:metabolism*; D004330:Drosophila / Q000196:embryology; D029721:Drosophila Proteins; D004625:Embryo, Nonmammalian / Q000378:metabolism*; D005775:Gastrula / Q000378:metabolism*; D006023:Glycoproteins / Q000378:metabolism; D019476:Insect Proteins / Q000378:metabolism; D036341:Intercellular Signaling Peptides and Proteins; D008666:Metalloendopeptidases / Q000378:metabolism; D009024:Morphogenesis; D011506:Proteins / Q000378:metabolism; D015398:Signal Transduction; D055394:Tolloid-Like Metalloproteinases; D016212:Transforming Growth Factor beta / Q000378:metabolism; D014981:Xenopus / Q000196:embryology; D029867:Xenopus Proteins
D019485:Bone Morphogenetic Proteins; D029721:Drosophila Proteins; D006023:Glycoproteins; D019476:Insect Proteins; D036341:Intercellular Signaling Peptides and Proteins; D011506:Proteins; C090223:TSG protein, Drosophila; D016212:Transforming Growth Factor beta; D029867:Xenopus Proteins; C064196:dpp protein, Drosophila; C091428:sog protein, Drosophila; C054234:chordin; D055394:Tolloid-Like Metalloproteinases; C071471:tld protein, Drosophila; D008666:Metalloendopeptidases; C109187:TLL2 protein, Xenopus