title: Corneal tissue mass in normal and keratoconic eyes. In vivo estimation based on area of horizontal optical sections.
abstract: Based on measurements of the corneal diameter, radius of curvature variation, and thickness profile a method for calculation of the horizontal meridian's sectional tissue mass area (M) is described. Pooled values of 52 normal eyes demonstrate M to be 8.57 mm2 +/- SD. Comparing one eye of 27 keratoconic patients with one eye of 28 normals established no significant difference in M. This result is in accordance with a hypothesis in which the keratoconic corneal thinning is a result of an increased sliding of collagen fibers rather than a result of increased collagen degradation.
authors.affiliation: Department of Ophthalmology, Gentofte Hospital, University of Copenhagen, Denmark.
authors.forename: C
authors.initials: C
authors.lastname: Edmund
mesh_terms: D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D003315:Cornea / Q000033:anatomy & histology / Q000473:pathology*; D005260:Female; D006801:Humans; D007640:Keratoconus / Q000145:classification / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012016:Reference Values