title: Double infection with a resistant and a multidrug-resistant strain of Mycobacterium tuberculosis.
abstract: An immunocompetent patient was dually infected with a resistant and a multidrug-resistant strain of Mycobacterium tuberculosis (TB). The multidrug-resistant strain, which belongs to the W- strain/Beijing family, was first isolated after 3 months of therapy. Inappropriate treatment led to further drug resistance and unsuccessful therapy. Thus, additional infections with resistant M. tuberculosis strains should be considered when tuberculosis therapy fails.
authors.affiliation: Forschungszentrum Borstel, National Reference Center for Mycobacteria, Borstel, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Niemann
authors.forename: E
authors.initials: E
authors.lastname: Richter
authors.forename: S
authors.initials: S
authors.lastname: Rüsch-Gerdes
authors.forename: M
authors.initials: M
authors.lastname: Schlaak
authors.forename: U
authors.initials: U
authors.lastname: Greinert
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D018432:Drug Resistance, Multiple; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D017211:Treatment Failure; D014374:Tuberculin Test; D014376:Tuberculosis / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents