title: [Methodological approaches to the study of the carcinogenic properties of substances].
abstract: Since the methods of investigation of carcinogenicity of different agents have changed drastically, relevant manuals need to be revised and supplemented. A new concept of carcinogenic agents evaluation, criteria for their selection and study are discussed. Working out of criteria for establishing priorities of hazardous substance selection is of vital importance.
authors.affiliation: N. N. Blokhin Center for Oncology Research, Russian Academy of Medical Sciences, Moscow.
authors.forename: L N
authors.initials: LN
authors.lastname: Pylev
authors.forename: L A
authors.initials: LA
authors.lastname: Vasil'eva
authors.forename: G B
authors.initials: GB
authors.lastname: Pliss
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D002273:Carcinogens / Q000008:administration & dosage / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D009374:Neoplasms, Experimental / Q000139:chemically induced; D012107:Research Design; D013997:Time Factors
chemical_list: D002273:Carcinogens