Sex steroids and osteoporosis. The role of estrogens and androgens.
Osteoporosis (low bone mass) depends on the peak bone mass attained and bone loss after the peak. Sex steroids (estrogens and androgens) have an impact on both processes. In this article the roles and mechanisms of estrogens and androgens are discussed in relation to clinical osteoporosis. Other hormones and hormone-like drugs, such as raloxifene, may be used to mimic the effects of natural sex steroids.
Adler
R A
RA
Section of Endocrinology and Metabolism, McGuire Veterans Affairs Medical Center, Richmond, Virginia, USA.
D000728:Androgens / Q000502:physiology* / Q000627:therapeutic use; D015519:Bone Density; D016723:Bone Remodeling; D004967:Estrogens / Q000502:physiology* / Q000627:therapeutic use; D006801:Humans; D010024:Osteoporosis / Q000188:drug therapy
D000728:Androgens; D004967:Estrogens