Olanzapine and obsessive-compulsive symptoms.
Clozapine and risperidone have been implicated in the development of obsessive-compulsive symptoms. We present three cases in which olanzapine caused a significant exacerbation of obsessive-compulsive symptoms in schizophrenia (two cases) and obsessive-compulsive disorder (one case).
Lykouras
L
L
Department of Psychiatry, Athens University Medical School, Eginition Hospital, 74 Vass. Sophias Avenue, 115 28, Athens, Greece. gnchrist@compulink.gr
Zervas
I M
IM
Gournellis
R
R
Malliori
M
M
Rabavilas
A
A
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001569:Benzodiazepines; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000139:chemically induced* / Q000523:psychology; D000077152:Olanzapine; D010890:Pirenzepine / Q000009:adverse effects* / Q000031:analogs & derivatives*; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy*
D014150:Antipsychotic Agents; D001569:Benzodiazepines; D010890:Pirenzepine; D000077152:Olanzapine