Self-assembly and lyomesophases formed by long-chain alkoxymethyl-nucleobase derivatives.
Amphiphilic complementary nucleobase derivatives, containing n-octadecyloxymethyl substituents at the N1 position of pyrimidine and N9 of purine, dissolved in chloroform form non-specific lyotropic mesophases, which were analyzed by optical polarizing microscopy. Molecular modeling studies visualize hypothetical horizontal and vertical nucleobase hydrogen-bonding and stacking arrangements, as well as aliphatic long-chain interstrand interaction.
Meister
W V
WV
Martin Luther University Halle-Wittenberg, Institute of Biochemistry, Halle, Saale, Germany. meister@biochemtech.uni-halle.de
Lindau
S
S
Bohley
C
C
Gromann
U
U
Madre
M
M
Kovalenko
L
L
Bischoff
G
G
Zhuk
R
R
Hoffmann
S
S
D002725:Chloroform / Q000737:chemistry; D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry*; D006860:Hydrogen Bonding; D008859:Microscopy, Polarization; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D009705:Nucleosides / Q000138:chemical synthesis*
D009705:Nucleosides; D002725:Chloroform; D004247:DNA