title: Pathogenesis and clinical manifestations of Clostridium difficile diarrhea and colitis.
authors.affiliation: Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Farrell
authors.forename: J T
authors.initials: JT
authors.lastname: LaMont
mesh_terms: D000328:Adult; D001426:Bacterial Proteins; D001427:Bacterial Toxins / Q000009:adverse effects; D002353:Carrier State / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D016360:Clostridioides difficile / Q000302:isolation & purification / Q000472:pathogenicity* / Q000502:physiology; D003015:Clostridium Infections / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D003092:Colitis / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D003106:Colon / Q000382:microbiology / Q000473:pathology; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology; D003967:Diarrhea / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D004198:Disease Susceptibility; D004761:Enterocolitis, Pseudomembranous / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D004768:Enterotoxins / Q000009:adverse effects; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015212:Inflammatory Bowel Diseases / Q000150:complications; D007416:Intestinal Perforation / Q000209:etiology; D012008:Recurrence; D012307:Risk Factors; D014456:Ulcer; D014774:Virulence; D020741:rho GTP-Binding Proteins / Q000037:antagonists & inhibitors / Q000502:physiology
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins; D004768:Enterotoxins; C041348:tcdA protein, Clostridium difficile; C031815:toxB protein, Clostridium difficile; D020741:rho GTP-Binding Proteins