title: Differences among mechanisms of ribozyme-catalyzed reactions.
abstract: The catalytic properties of ribozymes depend on the sophisticated structures of the respective ribozyme-substrate complexes. Although it has been suggested that ribozyme-mediated cleavage of RNA occurs via a rather strictly defined mechanism, recent findings have clearly demonstrated the diversity of reaction mechanisms.
authors.affiliation: Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Hongo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Warashina
authors.forename: Y
authors.initials: Y
authors.lastname: Takagi
authors.forename: W J
authors.initials: WJ
authors.lastname: Stec
authors.forename: K
authors.initials: K
authors.lastname: Taira
mesh_terms: D000143:Acids; D000818:Animals; D002384:Catalysis; D003698:Hepatitis Delta Virus / Q000235:genetics; D008670:Metals / Q000378:metabolism; D016337:RNA, Catalytic / Q000737:chemistry* / Q000378:metabolism*; D013768:Tetrahymena / Q000235:genetics
chemical_list: D000143:Acids; D008670:Metals; D016337:RNA, Catalytic