Mild cognitive impairment. When is it a precursor to Alzheimer's disease?
There is good evidence suggesting that onset of Alzheimer's disease is commonly preceded by an interim phase known as mild cognitive impairment (MCI). Persons who experience this condition are at increased risk for the development of Alzheimer's disease. Diagnosing MCI involves excluding other morbidities and determining whether the patient meets predefined assessment criteria. There is no treatment for the prevention of MCI, but an understanding of the condition can improve patient management. Several clinical trials are underway to investigate potential potential MCI agents.
Shah
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Mayo Clinic, Rochester, MN, USA.
Tangalos
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Petersen
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D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000517:prevention & control; D003072:Cognition Disorders / Q000175:diagnosis* / Q000188:drug therapy*; D018450:Disease Progression; D006801:Humans; D011379:Prognosis; D009626:Terminology as Topic