Familial occurrence of osteosarcoma. A case report and review of the literature.
We treated two cases of osteosarcoma in siblings. After intensive chemotherapy and surgery, both patients are alive after 9 and 4 years without any signs of disease. We report the course of disease in these patients in detail and review the literature on 59 patients with familial osteosarcomas.
Hillmann
A
A
Department of Orthopedics, Westfälische Wilhelms-Universität, Münster, Germany. hillmaa@uni-muenster.de
Ozaki
T
T
Winkelmann
W
W
D000293:Adolescent; D001859:Bone Neoplasms / Q000235:genetics*; D002648:Child; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D012516:Osteosarcoma / Q000235:genetics*