title: Carotid endarterectomy in octogenerians.
abstract: OBJECTIVE
  The purpose of this study was to determine the safety and efficacy of carotid endarterectomy (CEA) in octogenerians.
  
  
  METHODS
  The records of 59 CEA performed in 57 patients who were 80yr or older between April 1993 and September 1998 were reviewed. There were 33 males and 24 females with a mean age of 82. Forty-nine procedures (83%) were performed for symptomatic carotid stenosis. The perioperative mortality and morbidity including neurological events were recorded. Long term follow-up data was also obtained.
  
  
  RESULTS
  There were three perioperative deaths (5.1%) and three perioperative neurological events, including one stroke (1.7%) and two transient ischemic attacks (3.4%). The combined mortality and stroke rate was 6.8%. With a mean follow-up of 25+/-21months, Kaplan-Meier estimates of the 4-yr survival rate, freedom from stroke, and stroke free survival were 78, 94 and 75% respectively. For comparison, during the same time period, the same group of surgeons performed 597 CEA in patients less than 80yr of age. The perioperative mortality and stroke rate was 0.3 and 2.5% respectively, with a combined mortality and stroke rate of 2.7%. Perioperative mortality was significantly higher in patients over 80yr of age (P<0.01).
  
  
  CONCLUSIONS
  CEA in octogenerians is associated with a higher mortality rate than in younger patients. However, good long term survival and freedom from stroke make CEA beneficial in octogenerians. With careful patient selection and perioperative management, CEA in octogenerians is worthwhile and should be advised in selected patients.
authors.affiliation: Division of Vascular Surgery, Department of Surgery, University of British Columbia, BC, Vancouver, Canada.
authors.forename: A C
authors.initials: AC
authors.lastname: Ting
authors.forename: D C
authors.initials: DC
authors.lastname: Taylor
authors.forename: A J
authors.initials: AJ
authors.lastname: Salvian
authors.forename: J C
authors.initials: JC
authors.lastname: Chen
authors.forename: S
authors.initials: S
authors.lastname: Strandberg
authors.forename: Y N
authors.initials: YN
authors.lastname: Hsiang
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016893:Carotid Stenosis / Q000150:complications / Q000601:surgery*; D016894:Endarterectomy, Carotid; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000401:mortality; D012307:Risk Factors; D020521:Stroke / Q000209:etiology / Q000517:prevention & control