title: An antitumor pectic polysaccharide from Feronia limonia.
abstract: An acidic heteropolysaccharide has been isolated from the tropical angiosperm Feronia limonia syn. F. elephantum (family: Rutaceae). A partially carboxymethylated alpha-(1-4) polygalacturonan backbone structure with 2- and 2,4-O-alpha-L-rhamnopyranosyl, 2- and 2, 3-O-alpha-L-arabinofuranosyl and 3-, 2,4-and terminal alpha-D-galactopyranosyl bearing side chains has been tentatively assigned. The preliminary study in the murine model showed some significant in vivo Ehrlich ascites carcinoma cell growth inhibition.
authors.affiliation: Department of Chemistry, Indian Institute of Chemical Biology (IICB), 700032, Calcutta, India.
authors.forename: Y
authors.initials: Y
authors.lastname: Saima
authors.forename: A K
authors.initials: AK
authors.lastname: Das
authors.forename: K K
authors.initials: KK
authors.lastname: Sarkar
authors.forename: A K
authors.initials: AK
authors.lastname: Sen
authors.forename: P
authors.initials: P
authors.lastname: Sur
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D008264:Macrophages / Q000187:drug effects; D011134:Polysaccharides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D019685:Rosales / Q000737:chemistry*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D011134:Polysaccharides