title: [A case of acute urticaria from hydroxyzine hydrochloride used for preanesthetic medication].
abstract: We report a case of acute urticaria probably caused by hydroxyzine hydrochloride. A 66-year-old male was scheduled for cardiac cystectomy by thoracic endoscopy. The patient was premedicated with atropine and hydroxyzine intramuscularly 30 min before arrival in the operating room. Abrupt general exanthema was observed when intravenous infusion was started. Although his general condition was stable, the operation was postponed. Three days later, the skin test was performed using several drugs. Only hydroxyzine hydrochloride gave positive result. It is assumed that hydroxyzine hydrochloride may have caused his urticaria.
authors.affiliation: First Department of Anesthesiology, Dokkyo University School of Medicine, Tochigi.
authors.forename: K
authors.initials: K
authors.lastname: Urabe
authors.forename: K
authors.initials: K
authors.lastname: Fujii
authors.forename: M
authors.initials: M
authors.lastname: Tezuka
authors.forename: Y
authors.initials: Y
authors.lastname: Okuda
authors.forename: T
authors.initials: T
authors.lastname: Kitajima
authors.forename: T
authors.initials: T
authors.lastname: Yamazaki
authors.forename: A
authors.initials: A
authors.lastname: Yamakage
mesh_terms: D000208:Acute Disease; D000368:Aged; D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D006801:Humans; D006919:Hydroxyzine / Q000009:adverse effects*; D008297:Male; D011229:Preanesthetic Medication; D012882:Skin Tests; D014581:Urticaria / Q000139:chemically induced*
chemical_list: D014151:Anti-Anxiety Agents; D006919:Hydroxyzine