Synthesis of enantiomerically pure, sn-1 modified sn-2-deoxy-2-amido-glycero-3-phospholipids.
The synthesis of two types of enantiomerically pure sn-2-deoxy-2-amido-glycero-phospholipids differing in the connection of the alkyl chain at the sn-1-position is described. Both types of lipids were prepared from L-serine-methylester as the chiral starting material.
Bartel
M
M
Institut für Pharmazeutische Chemie, Martin-Luther-Universität Halle-Wittenberg, Wittenberg, Germany.
Rattay
B
B
Nuhn
P
P
D020404:Glycerophospholipids / Q000138:chemical synthesis* / Q000737:chemistry; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D010741:Phospholipases A / Q000737:chemistry; D013237:Stereoisomerism
D020404:Glycerophospholipids; D010741:Phospholipases A