title: Design of a magnetically integrated microporous implant.
abstract: OBJECTIVE
  To determine the orbital tolerance of a microporous implant fitted with an integrated stainless steel post and the enhanced motility associated with magnetic coupling of the prosthetic and the implant in a rabbit model.
  
  
  METHODS
  Six New Zealand white rabbits underwent primary enucleation with implantation of a 12-mm microporous polyethylene implant with a 2 x 3-mm stainless steel post embedded flush with the anterior surface. At 1 month, the rabbits were fitted with an external prosthesis containing two 1-mm circular rare earth dental magnets embedded at 0. 5 mm off the midline (right and left of center at the horizon). Magnetic coupling forces were determined with a hanging block technique.
  
  
  RESULTS
  No evidence of toxicity was observed in association with this integrated ocular implant. Magnetic coupling forces were noted maximally at 0.47 N. Clinical grading of motility documented enhancement in lateral excursion when compared with nonintegrated controls.
  
  
  CONCLUSIONS
  Magnetically integrated microporous implants achieve excellent enhancement of motility without evidence of complications in this rabbit model.
  
  
  CONCLUSIONS
  This study establishes a framework for the clinical evaluation of a magnetically integrated implant that may enhance prosthetic motility without requiring direct mechanical coupling of the implant to the prosthesis. Arch Ophthalmol. 2000;118:1259-1262
authors.affiliation: Department of Opthamology, Bascom Palmer Eye Institute, University of Miami School of Medicine, PO Box 016880, Miami, FL 33101, USA. tmurray@bpei.med.miami.edu
authors.forename: T G
authors.initials: TG
authors.lastname: Murray
authors.forename: N L
authors.initials: NL
authors.lastname: Cicciarelli
authors.forename: B H
authors.initials: BH
authors.lastname: Croft
authors.forename: S
authors.initials: S
authors.lastname: Garonzik
authors.forename: M
authors.initials: M
authors.lastname: Voigt
authors.forename: E
authors.initials: E
authors.lastname: Hernandez
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D015353:Eye Enucleation; D005133:Eye Movements; D005137:Eye, Artificial; D008280:Magnetics; D009915:Orbit / Q000601:surgery*; D020273:Orbital Implants; D020959:Polyethylene; D016062:Porosity; D011474:Prosthesis Design; D019919:Prosthesis Implantation; D011817:Rabbits
chemical_list: D001672:Biocompatible Materials; D020959:Polyethylene