title: Use of the endometrial pipelle in the diagnosis of early abnormal gestations.
abstract: OBJECTIVE
  To determine the sensitivity and specificity of the endometrial pipelle (Unimar, Wilton, CT) in detecting intrauterine chorionic villi, as compared to standard suction dilation and curettage (D and C).
  
  
  METHODS
  Prospective clinical study.
  
  
  METHODS
  U. S. Navy Hospital near Tokyo, Japan. Small community hospital.
  
  
  METHODS
  All patients presenting for the surgical management of an early abnormal gestation were enrolled prospectively. The patient's age, gravidy, parity, estimated gestational age (EGA), diagnosis, preoperative beta human chorionic gonadotropin (betahCG) level, and preoperative transvaginal ultrasound (TVUS) data were recorded.
  
  
  METHODS
  An endometrial biopsy was performed in the operating room prior to standard suction dilatation and curettage (D and C).
  
  
  METHODS
  The presence of chorionic villi in the endometrial biopsy and curettage specimens were recorded for each patient.
  
  
  RESULTS
  The sensitivity of the endometrial pipelle in detecting intrauterine chorionic villi was 63% and the specificity was 80%.
  
  
  CONCLUSIONS
  In the diagnosis of an early abnormal gestation, particularly in excluding an ectopic pregnancy, it would be ideal to replace the more invasive D and C with the outpatient endometrial biopsy in detecting intrauterine chorionic villi. However, the limited sensitivity of the endometrial biopsy limits its application in this clinical scenario. Our results compare with two previous studies and add to the limited patient database on this topic.
authors.affiliation: Department of Obstetrics and Gynecology, United States Naval Hospital, Yokosuka, Japan. annieries@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Ries
authors.forename: P
authors.initials: P
authors.lastname: Singson
authors.forename: M
authors.initials: M
authors.lastname: Bidus
authors.forename: J G
authors.initials: JG
authors.lastname: Barnes
mesh_terms: D000328:Adult; D001706:Biopsy; D002824:Chorionic Villi; D004107:Dilatation and Curettage; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000175:diagnosis*; D011296:Prenatal Diagnosis / Q000379:methods*; D011446:Prospective Studies; D012680:Sensitivity and Specificity