title: [Use of intrapleural urokinase in children].
abstract: OBJECTIVE
  To present the use of intrapleural urokinase as an alternative to surgical management of complicated pleural effusions in children. To add new cases to the literature and set bases for the development of a standardized protocol.
  
  
  METHODS
  Presentation of three cases in children under three years of age treated with intrapleural urokinase.
  
  
  RESULTS
  Resolution of the effusions with lack of adverse effects.
  
  
  CONCLUSIONS
  Treatment of pleural effusions when loculations develop. This invasive approach might be avoided in some cases by instillation of a fibrinolytic agent such as urokinase into the pleural space, this being an efficient and safe procedure.
authors.affiliation: Area de Pediatría, Hospital Costa del Sol, Marbella.
authors.forename: L
authors.initials: L
authors.lastname: Tapia Ceballos
authors.forename: B
authors.initials: B
authors.lastname: Picazo Angelín
authors.forename: A
authors.initials: A
authors.lastname: Bonillo Perales
authors.forename: J
authors.initials: J
authors.lastname: Romero Sánchez
authors.forename: R
authors.initials: R
authors.lastname: Díaz Cabrera
authors.forename: J
authors.initials: J
authors.lastname: Romero González
mesh_terms: D002675:Child, Preschool; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D007322:Instillation, Drug; D008297:Male; D010994:Pleura; D010996:Pleural Effusion / Q000188:drug therapy*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D005343:Fibrinolytic Agents; D014568:Urokinase-Type Plasminogen Activator