title: [Fisher's index as indicator of severity and its course in the postoperative period following liver transplantation in children].
abstract: OBJECTIVE
  To study the evolution of Fisher index during the early postoperative period after liver transplantation in children.
  
  
  METHODS
  We have studied 32 liver transplants performed on 26 pediatric patients, during the first week of the post-operative period. In all cases the BCAA/AAA quotient was determined before transplant, at the time of PICU admission, and on days 1, 2, 3, 4, 5, 6 and 7 after transplant.
  
  
  RESULTS
  Compared to control group values, the Fisher index for these patients is significantly lower at pre-transplant (p < 0,0001), upon admission (p < 0,001), and days 1 (p < 0,0001), 2 (p < 0,0001) and 3 (p < 0, 0001). Comparison between non-survivors and survivors shows a significant reduction in the first group on the index in days 1 (p < 0,02), 3 (p < 0,02), 4 (p < 0,005), 5 (p < 0,002), 6 (p < 0,03) and 7 (p < 0,01) of post-transplant.
  
  
  CONCLUSIONS
  The evolution of the Fisher index can be useful as an indication of the severity of the condition of these kinds of patients, which would help to establish more aggressive treatment to improve prognosis.
authors.affiliation: Servicio de Cuidados Intensivos Pediátricos, Hospital Infantil La Paz, Madrid.
authors.forename: M A
authors.initials: MA
authors.lastname: Delgado Domínguez
authors.forename: F
authors.initials: F
authors.lastname: Ruza Tarrío
authors.forename: V
authors.initials: V
authors.lastname: González Ojeda
authors.forename: P
authors.initials: P
authors.lastname: Dorao Martínez-Romillo
authors.forename: P
authors.initials: P
authors.lastname: de la Oliva Senovilla
authors.forename: F
authors.initials: F
authors.lastname: Goded Rambaud
authors.forename: F
authors.initials: F
authors.lastname: Alvarado Ortega
mesh_terms: D002648:Child; D006801:Humans; D016031:Liver Transplantation; D011182:Postoperative Care; D011446:Prospective Studies; D012720:Severity of Illness Index