title: Wear of high-dose gamma-irradiated polyethylene in total hip replacements.
abstract: Between 1971 and 1978, 62 patients underwent total hip replacements (THRs) with high-dose (100 Mrad) gamma-irradiated polyethylene sockets. After a mean follow-up of 17. 3 years (range, 6-23 years), 28 hips in 26 patients were available for radiographic wear measurement. Twenty-three THRs with non-irradiated sockets were used as controls, although all these hips had loosened within 13 years. The rate of linear wear in irradiated sockets was significantly lower throughout the follow-up period (less than 2 years, 0.16 and 0. 38 mm/year; 2-6 years, 0.05 and 0.29 mm/year; more than 6 years, 0. 05 and 0.28 mm/year, respectively; mean, P < 0.0001). This result has demonstrated that high-dose gamma-irradiated, cross-linked polyethylene is a promising articulating material for THRs.
authors.affiliation: Artificial Joint Section and Biomaterial Research Laboratory, Osaka-Minami National Hospital, 2-1 Kidohigashi-machi Kawachinagano, Osaka 586-8521, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Oonishi
authors.forename: Y
authors.initials: Y
authors.lastname: Kadoya
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging / Q000601:surgery*; D004307:Dose-Response Relationship, Radiation; D019544:Equipment Failure Analysis; D005260:Female; D005500:Follow-Up Studies; D005720:Gamma Rays; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000000981:diagnostic imaging / Q000601:surgery*; D020959:Polyethylene / Q000528:radiation effects*; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011474:Prosthesis Design; D011475:Prosthesis Failure; D011859:Radiography
chemical_list: D020959:Polyethylene