title: Neuroblastoma.
abstract: Neuroblastoma is a malignant tumor of neural crest origin that may arise anywhere along the sympathetic ganglia or within the adrenal medulla. The median age of diagnosis is 2 years; however occurrence is skewed toward younger children, with nearly 35% of cases occurring under 1 year of age and the remainder under 10 years of age. Seventy-five percent of neuroblastomas originate within the abdomen or pelvis, and half of these occur within the adrenal medulla, whereas 20% originate within the posterior mediastinum and 5% within the neck.
authors.affiliation: Department of Pediatric Surgery, Cleveland Clinic Children's Hospital, Ohio, USA.
authors.forename: F
authors.initials: F
authors.lastname: Alexander
mesh_terms: D002648:Child; D003582:Cytogenetics; D006801:Humans; D009447:Neuroblastoma / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D011379:Prognosis; D015996:Survival Rate; D014057:Tomography, X-Ray Computed