title: [Comparison of natural history of squamous cell carcinoma and nondifferentiated carcinoma localized in oro- and nasopharynx].
abstract: Aim of this study is comparison of natural history between two subtypes of cancer: squamous and undifferentiated, which were localised in oro- and nasopharynx. Analysis has contained 175 patients with undifferentiatied and 510 patients with squamous cell cancers of oro- and nasopharynx, who were treated in Centre of Oncology--Institute branch Gliwice in 1980-1998. Presence of undiferentiated subtypes were bounded with shortening time of presence the symptoms of disease, most frequent exophytic type of infiltration than in squamous cancer with ulcerative--necrotic type of infiltration. Higher aggressiveness of undifferentiated cancer is based on higher frequency of distant and nodal metastases, metastases to contralateral nodes and higher percentage of conglomerates.
authors.affiliation: I Klinika Radioterapii, Centrum Onkologii, Instytutu im. M. Skłodowskiej-Curie, Oddział w Gliwicach.
authors.forename: M
authors.initials: M
authors.lastname: Syguła
authors.forename: K
authors.initials: K
authors.lastname: Składowski
authors.forename: J
authors.initials: J
authors.lastname: Wydmański
authors.forename: W
authors.initials: W
authors.lastname: Sasiadek
authors.forename: A
authors.initials: A
authors.lastname: Wygoda
mesh_terms: D002277:Carcinoma / Q000175:diagnosis*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis*; D009367:Neoplasm Staging; D009959:Oropharyngeal Neoplasms / Q000175:diagnosis*; D012189:Retrospective Studies