title: Bioactive carotanes from Trichoderma virens.
abstract: Four new metabolites with carotane skeletons, trichocaranes A (1), B (2), C (3), and D (4), were isolated from Trichoderma virens and their structures established by the interpretation of NMR and mass spectroscopic data. The trichocaranes significantly inhibited the growth of etiolated wheat coleoptiles: 40% at 10(-4) M with 1 and 2 and 86% at 10(-3) M with 3.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Apdo. 40, 11510-Puerto Real, Cádiz, Spain. famacias@uca.es
authors.forename: F A
authors.initials: FA
authors.lastname: Macías
authors.forename: R M
authors.initials: RM
authors.lastname: Varela
authors.forename: A M
authors.initials: AM
authors.lastname: Simonet
authors.forename: H G
authors.initials: HG
authors.lastname: Cutler
authors.forename: S J
authors.initials: SJ
authors.lastname: Cutler
authors.forename: M A
authors.initials: MA
authors.lastname: Eden
authors.forename: R A
authors.initials: RA
authors.lastname: Hill
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D014242:Trichoderma / Q000737:chemistry*; D014908:Triticum / Q000187:drug effects* / Q000254:growth & development
chemical_list: D012717:Sesquiterpenes