Aristolactams and dioxoaporphines from Fissistigma balansae and Fissistigma oldhamii.
Investigation of extracts of Fissistigma balansae and Fissistigma oldhamii resulted in the isolation of 11 aristolactams-stigmalactam (1), piperolactam A (2), piperolactam C (3), aristolactam AII (4), aristolactam AIIIa (5), aristolactam BII (6), aristolactam BIII (7), aristolactam FII (8), goniothalactam (9), enterocarpam I (10), and velutinam (11)-as well as two dioxoaporphines, noraristolodione (12) and norcepharadione B (13). The new compound 1 was identified by spectral data interpretation. Compounds 1-13 were subjected to antiplatelet aggregation testing.
Chia
Y C
YC
Tajen Institute of Technology, Ping Tung Hsien 907, Taiwan.
Chang
F R
FR
Teng
C M
CM
Wu
Y C
YC
D000818:Animals; D001681:Biological Assay; D001792:Blood Platelets / Q000187:drug effects; D002449:Cell Aggregation / Q000187:drug effects; D002681:China; D002850:Chromatography, Gel; D002855:Chromatography, Thin Layer; D008401:Gas Chromatography-Mass Spectrometry; D007769:Lactams / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D010616:Phenanthrenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018547:Plant Stems / Q000737:chemistry*; D010944:Plants / Q000737:chemistry; D011817:Rabbits; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013624:Taiwan
D007769:Lactams; D010616:Phenanthrenes; C414695:stigmalactam