title: Absolute configuration at C45 in 45-hydroxyyessotoxin, a marine polyether toxin isolated from shellfish.
abstract: The marine polyether toxin, 45-hydroxyyessotoxin, was isolated together with yessotoxin from the scallop, Patinopecten yessoensis. The 45-hydroxy group in the side chain was esterified with (S)- and (R)-alpha-methoxyalpha-trifluoromethylphenylacetic acids (MTPA). A detailed analysis of the 2D NMR spectra of the two esters established the R configuration at C45.
authors.affiliation: Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Morohashi
authors.forename: M
authors.initials: M
authors.lastname: Satake
authors.forename: Y
authors.initials: Y
authors.lastname: Oshima
authors.forename: T
authors.initials: T
authors.lastname: Yasumoto
mesh_terms: D000818:Animals; D004988:Ethers, Cyclic / Q000737:chemistry*; D008956:Models, Chemical; D008974:Mollusca / Q000737:chemistry*; D008978:Mollusk Venoms / Q000302:isolation & purification*; D035964:Oxocins
chemical_list: C419348:45-hydroxyyessotoxin; D004988:Ethers, Cyclic; D008978:Mollusk Venoms; D035964:Oxocins; C066632:yessotoxin