title: [Progressive multifocal leukoencephalopathy an chronic lymphocytic leukemia].
abstract: BACKGROUND
  Progressive multifocal leukoencephalopathy is a demyelinating disease resulting from an opportunistic infection of the central nervous system by JC papovavirus. It mostly occurs in patients with an underlying immunosuppressive disorder. In the era of acquired immunodeficiency syndrome it is observed with increasing frequency.
  
  
  METHODS
  We report the case of a non-HIV-infected patient who presented chronic lymphocytic leukemia with progressive multifocal leukoencephalopathy uncovered by both imaging and the presence of JC virus in the cerebrospinal fluid.
  
  
  CONCLUSIONS
  Due to the lack of specific treatment, the disease is still rapidly progressive and fatal.
authors.affiliation: Service de neurologie, centre hospitalier, Belfort, France.
authors.forename: H
authors.initials: H
authors.lastname: Attout
authors.forename: F
authors.initials: F
authors.lastname: Rahmeh
authors.forename: G
authors.initials: G
authors.lastname: Lehuede
authors.forename: M
authors.initials: M
authors.lastname: Girardel
authors.forename: F
authors.initials: F
authors.lastname: Ziegler
mesh_terms: D000368:Aged; D006801:Humans; D007577:JC Virus / Q000302:isolation & purification*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000134:cerebrospinal fluid / Q000150:complications* / Q000175:diagnosis; D007968:Leukoencephalopathy, Progressive Multifocal / Q000134:cerebrospinal fluid / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male