title: [Anticoagulant treatment in pericardial effusion--a therapeutic dilemma].
abstract: Anticoagulant treatment for acute myocardial infarction (AMI) and pericardial effusion is controversial, since the treatment might cause hemopericardium and tamponade. On the other hand, anticoagulants are strongly indicated in many situations in AMI, including: left ventricular thrombus, unstable angina, severe heart failure, deep vein thrombophlebitis, pulmonary embolism, atrial fibrillation, as part of thrombolytic treatment, and during cardiac catheterization. We describe a 70-year-old man who presented with both pericardial effusion and a left ventricular thrombus 3 weeks after an extensive, anterior wall AMI. Anticoagulants and corticosteroids were administered simultaneously under hemodynamic and echocardiographic monitoring without complications. It is our impression that anticoagulant treatment is safe in patients with pericardial effusion.
authors.affiliation: Dept. of Medicine C, Assaf Harofeh Medical Center, Zerifin.
authors.forename: M
authors.initials: M
authors.lastname: Katsman
authors.forename: E
authors.initials: E
authors.lastname: Shiloah
authors.forename: M
authors.initials: M
authors.lastname: Rappoport
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D004452:Echocardiography; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy*; D010490:Pericardial Effusion / Q000150:complications / Q000188:drug therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D000925:Anticoagulants