title: [Intralesional methotrexate injection: an effective time and cost saving therapy alternative in keratoacanthomas that are difficult to treat surgically].
abstract: A 53 year old female patient developed a keratoacanthoma, present on the left side of her nose for two months. After repeated unsuccessful trials with cryotherapy, she was treated with intralesional injection of methotrexate performed twice with a weekly internal. This led to complete resolution within 5 weeks. Although controlled studies on the effect of methotrexate in keratoacanthoma are not available, the rapid regression and the good cosmetic result suggest that this therapy may play a beneficial role in treating these lesions especially in problem locations.
authors.affiliation: Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Technischen Universität München.
authors.forename: R
authors.initials: R
authors.lastname: Remling
authors.forename: M
authors.initials: M
authors.lastname: Mempel
authors.forename: N
authors.initials: N
authors.lastname: Schnopp
authors.forename: D
authors.initials: D
authors.lastname: Abeck
authors.forename: J
authors.initials: J
authors.lastname: Ring
mesh_terms: D003879:Dermatologic Agents / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015552:Injections, Intralesional; D007636:Keratoacanthoma / Q000188:drug therapy*; D008727:Methotrexate / Q000008:administration & dosage*; D008875:Middle Aged; D013997:Time Factors
chemical_list: D003879:Dermatologic Agents; D008727:Methotrexate