Successful immunoglobulin treatment in a patient with neuromyotonia.
Neuromyotonia is characterized by spontaneous and continuous muscle fibre activity leading to muscle cramps, pseudomyotonia, myokymia and weakness. Electromyographic recordings show typical findings. An auto-immune mechanism has been suggested in at least a subset of patients. Various therapies have been tried with different outcome. A patient with neuromyotonia responding well to high-dose immunoglobulin treatment is presented.
Alessi
G
G
Department of Neurology, University Hospital Ghent, De Pintelaan, 185 Ghent, Belgium.
De Reuck
J
J
De Bleecker
J
J
Vancayzeele
S
S
D015551:Autoimmunity; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004576:Electromyography; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage / Q000627:therapeutic use*; D020386:Isaacs Syndrome / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011115:Polyneuropathies / Q000150:complications; D012074:Remission Induction
D016756:Immunoglobulins, Intravenous