Undecylenic acid inhibits morphogenesis of Candida albicans.
Resilient liners are frequently used to treat denture stomatitis, a condition often associated with Candida albicans infections. Of 10 liners tested, 2 were found to inhibit the switch from the yeast form to hyphae and a third was found to stimulate this switch. The inhibitor was determined to be undecylenic acid.
McLain
N
N
Molecular and Cellular Biology & Pathobiology Program, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
Ascanio
R
R
Baker
C
C
Strohaver
R A
RA
Dolan
J W
JW
D002176:Candida albicans / Q000187:drug effects* / Q000648:ultrastructure; D003822:Denture Liners / Q000382:microbiology; D003864:Depression, Chemical; D006801:Humans; D009024:Morphogenesis; D014476:Undecylenic Acids / Q000494:pharmacology*
D014476:Undecylenic Acids