Ability of peritoneal exudate cells to trigger various mechanisms of erythroid differentiation at different terms after massive blood loss in mice.
Thirty minutes after massive blood loss, peritoneal cells gained the ability to trigger reparative erythropoiesis in the bone marrow of normal syngeneic recipients. This was manifested in proliferation of oxyphilic erythroblasts and activation of the reserve pathway of erythroid differentiation 4 days after cell transplantation. The maximum transfer capacity of peritoneal cells was observed 4 h after blood loss, but 4 days later they only initiated mitoses in oxyphilic erythroblasts.
Belan
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EI
Laboratory of Growth and Development, Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow. katebelan@yahoo.com
D019264:Adoptive Transfer; D000818:Animals; D001202:Ascitic Fluid / Q000473:pathology*; D002450:Cell Communication; D002454:Cell Differentiation; D004920:Erythropoiesis; D006470:Hemorrhage; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D013997:Time Factors