Asthma, skin symptoms, and allergy in a condom factory.
BACKGROUND
Cases of occupational asthma have been reported in condom factories in the UK and France, but there has been no epidemiologic study of groups of workers in such factories. This investigation aimed to study the prevalence of symptoms in a Swedish condom factory, to determine groups at special risk, and to suggest preventive measures.


METHODS
A questionnaire was mailed to 35 employees, 29 women and six men with mean ages of 37 and 32 years, respectively. All subjects were interviewed by a physician and underwent skin prick test with latex and epicutaneous testing with 39 substances, and blood samples were taken for allergy testing.


RESULTS
Phadiatop was positive in 23%, RAST against Lycopodium in 31%, and RAST against latex in one of these 11. Ten subjects (29%) had work-related nose/eye symptoms; of these, eight had positive RAST to Lycopodium; three also had symptoms of occupational asthma and contact urticaria. Only one had positive RAST to latex. Five of the nine subjects with positive Phadiatop also had positive RAST to Lycopodium. All those with RAST positive to Lycopodium had worked in packaging, the area of the factory with the greatest exposure. The results of the patch tests did not correlate with the work-related symptoms.


CONCLUSIONS
In a Swedish condom factory, there were a high prevalence of rhinoconjunctivitis and a small number of cases of asthma and contact urticaria caused by allergy to Lycopodium.
Rask-Andersen
A
A
Department of Occupational and Environmental Medicine, University Hospital, Uppsala, Sweden.
Boman
J
J
Grängsjö
A
A
Silverdal
M
M
Lindberg
M
M
Lundberg
M
M
Svensson
L
L
D000328:Adult; D001249:Asthma / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology; D017280:Condoms; D003233:Conjunctivitis, Allergic / Q000453:epidemiology / Q000209:etiology / Q000276:immunology; D009783:Dermatitis, Occupational / Q000453:epidemiology; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology; D007221:Industry; D007840:Latex / Q000009:adverse effects; D020315:Latex Hypersensitivity / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology; D008297:Male; D009784:Occupational Diseases / Q000453:epidemiology* / Q000209:etiology; D010328:Patch Tests; D010944:Plants; D015995:Prevalence; D011852:Radioallergosorbent Test; D012221:Rhinitis, Allergic, Perennial / Q000453:epidemiology / Q000209:etiology / Q000276:immunology; D013170:Spores / Q000276:immunology; D011795:Surveys and Questionnaires; D014581:Urticaria / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology
D007840:Latex