title: [Results of the surgical treatment of pathologic bronchogenic carcinoma N2 with negative mediastinoscopy].
abstract: OBJECTIVE
  To analyze the survival of patients undergoing lung resection for N2 bronchogenic carcinoma with negative findings at mediastinoscopy.
  
  
  METHODS
  Twenty-nine patients with N2 bronchogenic carcinoma were analyzed. The patients were taken from a series of 170 patients who underwent surgery between 1993 and 1997 and whose data were recorded by the Bronchogenic Carcinoma Cooperative Group of the Spanish Society of Pneumology and Thoracic Surgery (GCCB-S). In 26 patients, nodes were found in the upper mediastinum; in three patients nodes were paraesophageal or in the area of the pulmonary ligament. In 11 cases, extracapsular nodal disease was found. Three patients who died in the postoperative period were excluded from survival analysis.
  
  
  RESULTS
  The five-year survival rate for the series of 170 patients was 39%. For the 26 patients with N2 carcinoma, five-year survival was 14% (median 12 months). Five-year survival for the remaining patients (excluding those with N2 carcinoma) was 46%. Although the median survival of patients with intracapsular nodal disease was more than twice (25 months) that of patients with extracapsular nodal disease (12 months), the difference was not significant.
  
  
  CONCLUSIONS
  Lung resection in patients with N2 bronchogenic carcinoma with negative mediastinoscopy has little impact on survival. Surgical exploration of the mediastinum classifies such patients with greatest certainty, although the sensitivity of staging techniques warrants improvement to assure that thoracotomy is not used unnecessarily.
authors.affiliation: Sección de Cirugía Torácica, Hospital Mútua de Terrassa, Barcelona. rramip@teleline.es
authors.forename: R
authors.initials: R
authors.lastname: Rami Porta
authors.forename: M
authors.initials: M
authors.lastname: Mateu Navarro
authors.forename: G
authors.initials: G
authors.lastname: González Pont
authors.forename: M
authors.initials: M
authors.lastname: Cuesta Palomero
mesh_terms: D000328:Adult; D000368:Aged; D002283:Carcinoma, Bronchogenic / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery*; D008297:Male; D008481:Mediastinoscopy; D008875:Middle Aged; D009367:Neoplasm Staging; D015996:Survival Rate