title: Hypertrophic synapses as a factor of formation of persistent pathological centers in the brain in the late postresuscitation period.
abstract: Clinical death was modelled on albino rats. Synapses in the molecular layer of the cerebral sensorimotor cortex were investigated 1, 2, 3, 4, 5, 6, 7, 8, and 9 months postresuscitation. The total density of synapses peaked and the number of hypertrophic and perforated contacts increased 4, 7, and 9 months after resuscitation. The role of increased number of hypertrophic and perforated contacts in the pathogenesis of postresuscitation encephalopathy is discussed.
authors.affiliation: Department of Histology and Embryology, Omsk Medical Academy.
authors.forename: V V
authors.initials: VV
authors.lastname: Semchenko
authors.forename: S S
authors.initials: SS
authors.lastname: Stepanov
authors.forename: A K
authors.initials: AK
authors.lastname: Desyatnichenko
mesh_terms: D000818:Animals; D002452:Cell Count; D009044:Motor Cortex / Q000473:pathology*; D009474:Neurons / Q000473:pathology*; D051381:Rats; D012151:Resuscitation; D013569:Synapses / Q000473:pathology*