Combined disorders in erythro- and immunopoiesis in (C57Bl/6xDBA/2)F1 mice with immunodeficiency induced by graft-versus-host reaction and immunocomplex glomerulonephritis.
Disorders in erythro- and immunopoiesis were studied in B6D2F1 mice with immunodeficiency induced by graft versus host reaction and with immunocomplex glomerulonephritis. By the 6th-7th months of the disease the animals developed anemia accompanied by enhanced phagocytic activity of macrophages and production of tumor necrosis factor. Macrophage dysfunction is presumed to be a cause of anemia.
Sukhenko
T G
TG
Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk. tata@mezon.nsk-su
Kolesnikova
O P
OP
Kozlov
V A
VA
D000818:Animals; D000936:Antigen-Antibody Complex / Q000276:immunology; D004920:Erythropoiesis; D005921:Glomerulonephritis / Q000276:immunology*; D006086:Graft vs Host Disease / Q000276:immunology* / Q000503:physiopathology*; D007165:Immunosuppression Therapy; D019891:Leukopoiesis; D051379:Mice
D000936:Antigen-Antibody Complex