Studies on arylfuran derivatives. Part XI. Synthesis, characterisation and biological studies on some Mannich bases carrying 2,4-dichlorophenylfurfural moiety.
A series of 3-substituted-4-[5-(2,4-dichlorophenyl)-2-furfurylidine]amino-5-me rcapto-1, 2,4-triazoles (3) are synthesised. Aminomethylation of 3 with formaldehyde and a primary/secondary amine furnished Mannich bases 4 and 5. Both Schiff bases 3 and Mannich bases 4 and 5 are characterised on the basis of IR, 1H NMR, mass spectral data and elemental analysis. All the newly synthesised compounds are tested for their antibacterial activities. Some of the selected compounds are also tested for their fungicidal and herbicidal properties.
Holla
B S
BS
Department of P.G. Studies and Research in Chemistry, Mangalore University, Mangalagangothri, India. hollabs@yahoo.com
Rao
B S
BS
Shridhara
K
K
Akberali
P M
PM
D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D005662:Furaldehyde / Q000031:analogs & derivatives* / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D006540:Herbicides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D008352:Mannich Bases / Q000737:chemistry*; D015394:Molecular Structure; D013057:Spectrum Analysis
D000890:Anti-Infective Agents; D005663:Furans; D006540:Herbicides; D008352:Mannich Bases; D005662:Furaldehyde