[A genetic analysis of variants of the human immunodeficiency virus type 1 (HIV-1) circulating among drug abusers in Moscow and Moscow Province].
The genetic analysis of the variants of human immunodeficiency virus of type 1 (HIV-1), circulating among drug addicts in Moscow and Moscow Province, has been carried out. The serological analysis of 122 blood specimens taken from HIV-infected drug addicts, residing in Moscow and 22 settlements of the Moscow region, has shown that in this region HIV-1 variant of subtype A spreads among drug addicts. These data have been confirmed by the results of the analysis of 44 specimens, made with the use of the method of the heteroduplex mobility assay for gene env. As revealed in this study, HIV-1 variants spreading at present among drug addicts in Moscow and the Moscow region are genetically related to viruses of subtype A, detected earlier in this group of risk in other regions of Russia, the Ukraine, Belarus and other countries of Eastern Europe.
Bobkov
A F
AF
Ivanovsky Research Institute of Virology, Russian Research and Methodological Center for Prevention and Control of AIDS, Moscow, Russia.
Kazennova
E V
EV
Bobkova
M R
MR
Selimova
L M
LM
Buravtsova
E V
EV
Ladnaia
N N
NN
Khanina
T A
TA
Kravchenko
A V
AV
Pokrovskiĭ
V V
VV
D001483:Base Sequence; D005260:Female; D014644:Genetic Variation / Q000235:genetics*; D005838:Genotype; D015658:HIV Infections / Q000821:virology*; D015497:HIV-1 / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D009031:Moscow; D010802:Phylogeny; D012424:Rural Population; D012426:Russia; D012703:Serotyping; D019966:Substance-Related Disorders / Q000821:virology*; D014505:Urban Population