title: Improvement of oxidative stability of conjugated linoleic acid (CLA) by microencapsulation in cyclodextrins.
abstract: Oxidative stability of conjugated linoleic acid (CLA) encapsulated in alpha-, beta-, and gamma-cyclodextrins (designated CLA/CDs microencapsules) was studied by measuring the headspace-oxygen depletion in airtight serum bottles and by measuring the peroxide values (POV). The rate of oxygen depletion was reduced from 41.0 (control) to 21.5, 2.1, 1.2, and 1.1 micromol/L.h(-)(1) by CLA/alpha-CD microencapsules at 1:1, 1:2, 1:4, and 1:6 mole ratios, respectively, indicating that CLA oxidation was completely protected by a 1:4 mole ratio of CLA/alpha-CD. Such a protective effect by CLA/beta-CD or CLA/gamma-CD microencapsules was achieved at a 1:6 mole ratio, but the effect by CLA/beta-CD was slightly greater than that by CLA/gamma-CD. The protective effect of alpha-, beta-, and gamma-CDs for CLA oxidation was confirmed by their POV-reducing abilities in CLA/CDs. These results suggest that alpha-CD was the most effective for the protection of CLA oxidation by microencapsulation, followed by beta-CD and gamma-CD.
authors.affiliation: Department of Agricultural Chemistry, Animal Science and Veterinary Medicine, and Central Laboratory, Gyeongsang National University, Chinju 660-701, Korea.
authors.forename: S J
authors.initials: SJ
authors.lastname: Kim
authors.forename: G B
authors.initials: GB
authors.lastname: Park
authors.forename: C B
authors.initials: CB
authors.lastname: Kang
authors.forename: S D
authors.initials: SD
authors.lastname: Park
authors.forename: M Y
authors.initials: MY
authors.lastname: Jung
authors.forename: J O
authors.initials: JO
authors.lastname: Kim
authors.forename: Y L
authors.initials: YL
authors.lastname: Ha
mesh_terms: D003505:Cyclodextrins / Q000737:chemistry*; D004339:Drug Compounding; D019787:Linoleic Acid / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction
chemical_list: D003505:Cyclodextrins; D019787:Linoleic Acid