title: Large clostridial cytotoxins as tools in cell biology.
authors.affiliation: Institut für Pharmakologie und Toxikologie, Universität Freiburg, Germany.
authors.forename: I
authors.initials: I
authors.lastname: Just
authors.forename: P
authors.initials: P
authors.lastname: Boquet
mesh_terms: D000818:Animals; D001426:Bacterial Proteins; D001427:Bacterial Toxins / Q000737:chemistry / Q000494:pharmacology*; D016466:CHO Cells / Q000187:drug effects; D002460:Cell Line; D002465:Cell Movement / Q000187:drug effects; D003013:Clostridium / Q000737:chemistry / Q000502:physiology*; D006224:Cricetinae; D003599:Cytoskeleton / Q000187:drug effects; D004705:Endocytosis / Q000187:drug effects; D004768:Enterotoxins / Q000737:chemistry / Q000494:pharmacology*; D004847:Epithelial Cells / Q000187:drug effects; D005089:Exocytosis / Q000187:drug effects; D005347:Fibroblasts / Q000187:drug effects; D005786:Gene Expression Regulation / Q000187:drug effects; D005964:Glucosyltransferases / Q000737:chemistry / Q000494:pharmacology*; D020935:MAP Kinase Signaling System / Q000187:drug effects; D008407:Mast Cells / Q000187:drug effects; D011956:Receptors, Cell Surface / Q000187:drug effects; D013912:Threonine / Q000378:metabolism; D014407:Tumor Cells, Cultured / Q000187:drug effects; D014532:Uridine Diphosphate Glucose / Q000378:metabolism; D018631:ras Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000502:physiology; D020741:rho GTP-Binding Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000502:physiology
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins; C075216:Clostridium novyi alpha-toxin; D004768:Enterotoxins; D011956:Receptors, Cell Surface; C072293:hemorrhagic toxin HT, Clostridium sordellii; C072292:lethal toxin LT, Clostridium sordellii; C041348:tcdA protein, Clostridium difficile; C031815:toxB protein, Clostridium difficile; D013912:Threonine; D005964:Glucosyltransferases; D018631:ras Proteins; D020741:rho GTP-Binding Proteins; D014532:Uridine Diphosphate Glucose