title: Enantioselective copper-catalyzed conjugate addition of dialkyl zinc to nitro-olefins
abstract: [reaction: see text]The copper-catalyzed asymmetric conjugate addition of dialkylzinc onto various nitro-olefins has been carried out with excellent results. An enantiomeric excess of up to 94% was obtained using 0.5% Cu(OTf)2 and 1% of chiral trivalent phosphorus ligand.
authors.affiliation: Department of Organic Chemistry, University of Geneva, Switzerland. alexandre.alexakis@chiorg.unige.ch
authors.initials: A
authors.lastname: Alexakis
authors.initials: C
authors.lastname: Benhaim