Cardiac insulin resistance is associated with an impaired recruitment of phosphatidylinositol 3-kinase to GLUT4 vesicles.
Eckel
J
J
Molecular Cardiology, Diabetes Research Institute, Düsseldorf, Germany. eckel@uni-dusseldorf.de
Till
M
M
Uphues
I
I
D000818:Animals; D051275:Glucose Transporter Type 4; D006321:Heart / Q000187:drug effects*; D007163:Immunosorbent Techniques; D007328:Insulin / Q000494:pharmacology*; D007333:Insulin Resistance; D009004:Monosaccharide Transport Proteins / Q000378:metabolism*; D009124:Muscle Proteins; D009206:Myocardium / Q000378:metabolism; D009765:Obesity / Q000378:metabolism*; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D019000:Phosphotyrosine / Q000378:metabolism; D051381:Rats; D011924:Rats, Zucker
D051275:Glucose Transporter Type 4; D007328:Insulin; D009004:Monosaccharide Transport Proteins; D009124:Muscle Proteins; C495694:Slc2a4 protein, rat; D019000:Phosphotyrosine; D019869:Phosphatidylinositol 3-Kinases