title: Acinic cell carcinoma of the oral cavity.
abstract: A rare case of acinic cell carcinoma of minor salivary gland origin within the oral cavity is reported in a 62-year-old woman. These tumors most commonly arise in the parotid gland and follow an insidious course requiring long-term follow-up. The gross and histologic features of the patient's tumor include pseudoencapsulation, mixed solid and acinar architecture, microcyst formation, and the presence of conspicuous diastase-fast and PAS-positive cytoplasmic granules, characteristic of lesions that have been called acinic cell carcinoma by a variety of authors. Surgical excision is the treatment of choice. However, following an incisional biopsy, the patient refused further surgical treatment and has remained clinically disease-free three years postoperatively.
authors.affiliation: Department of Otorhinolaryngology, Pennsylvania Hospital, Philadelphia 19107, USA.
authors.forename: W M
authors.initials: WM
authors.lastname: Keane
authors.forename: J C
authors.initials: JC
authors.lastname: Denneny
authors.forename: J P
authors.initials: JP
authors.lastname: Atkins
authors.forename: F
authors.initials: F
authors.lastname: McBrearty
mesh_terms: D000539:Alveolar Process / Q000473:pathology; D001706:Biopsy; D018267:Carcinoma, Acinar Cell / Q000473:pathology*; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008441:Maxillary Neoplasms / Q000473:pathology*; D008875:Middle Aged; D012468:Salivary Gland Neoplasms / Q000473:pathology*; D012470:Salivary Glands, Minor / Q000473:pathology*