title: Fundamentals of biomechanics in tissue engineering of bone.
abstract: The objective of this review is to provide basic information pertaining to biomechanical aspects of bone as they relate to tissue engineering. The review is written for the general tissue engineering reader, who may not have a biomechanical engineering background. To this end, biomechanical characteristics and properties of normal and repair cortical and cancellous bone are presented. Also, this chapter intends to describe basic structure-function relationships of these two types of bone. Special emphasis is placed on salient classical and modern testing methods, with both material and structural properties described.
authors.affiliation: Department of Bioengineering, Rice University, Houston, Texas 77251-1892, USA. athanasiou@rice.edu
authors.forename: K A
authors.initials: KA
authors.lastname: Athanasiou
authors.forename: C
authors.initials: C
authors.lastname: Zhu
authors.forename: D R
authors.initials: DR
authors.lastname: Lanctot
authors.forename: C M
authors.initials: CM
authors.lastname: Agrawal
authors.forename: X
authors.initials: X
authors.lastname: Wang
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001698:Biomedical Engineering; D001842:Bone and Bones / Q000502:physiology*; D017102:Fracture Healing / Q000502:physiology; D006801:Humans; D008422:Materials Testing; D013314:Stress, Mechanical; D013718:Tensile Strength