title: [Doppler tissue imaging of the mitral annulus in patients with left ventricular systolic dysfunction. Assessment of diastolic function].
abstract: OBJECTIVE
  We assessed the Doppler tissue imaging technique in the left mitral annulus of patients with left ventricular systolic dysfunction since the technique has been used to evaluate diastolic function of the left ventricle and the values obtained have been considered to be relatively independent of the preload.
  
  
  METHODS
  Patients (n = 46) with an ejection fraction < 40% in sinus rhythm without mitral regurgitation underwent pulsed wave Doppler analyses of mitral inflow (E and A waves), pulmonary venous flow (S, D and Ar waves) and Doppler tissue imaging of the mitral annulus (Ea and Aa waves).
  
  
  RESULTS
  Overall, the linear correlations between the different Doppler measurements were poor. When sub-grouped with respect to E/A < 1 and E/A >= 1 (Groups 1 and 2, respectively), the Ea value did not significantly differ between the two groups: 5.0 cm/s (4.2/6.0) vs 6.2 cm/s (5.5/8. 2) respectively; p = 0.129 and neither did the E/Ea quotient: 10.2 (8.2/14.5) vs 12.9 (9.1/17.4) respectively; p = 0.160. Atrial size was significantly greater in Group 2: 20.0 cm2 (18.0/22.0) vs 25.0 cm2 (20.0/29.0) respectively; p = 0.000. The Ea/Aa quotient was pseudo-normalized in Group 2: 0.65 (0.48/0.83) vs 1.15 (0.75/1.71) respectively; p = 0.001.
  
  
  CONCLUSIONS
  In patients with left ventricular systolic dysfunction the Ea/Aa value tends towards pseudo-normalization when the preload is increased. This does not apply to the values of Ea, E/Ea or to size of the left atrium. Therefore, Doppler tissue imaging of the left mitral annulus is valuable in the assessment of left ventricular dysfunction and the problem of pseudo-normalization due to preloading.
authors.affiliation: Laboratorio de Cardiología no Invasiva. Servicio de Cardiología. Hospital de León. León. med016340@nacom.es
authors.forename: I
authors.initials: I
authors.lastname: Iglesias Garriz
authors.forename: M A
authors.initials: MA
authors.lastname: Rodríguez García
authors.forename: S
authors.initials: S
authors.lastname: Delgado Fernández
authors.forename: C
authors.initials: C
authors.lastname: Garrote Coloma
authors.forename: M
authors.initials: M
authors.lastname: Sastre Ibarretxe
authors.forename: F
authors.initials: F
authors.lastname: Corral Fernández
mesh_terms: D000368:Aged; D003971:Diastole / Q000502:physiology; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology; D016277:Ventricular Function, Left