title: [Genetics of congenital cardiopathies].
abstract: Congenital heart malformations are the most common of all birth defects, affecting 0.5-1% of all live births. Some of these malformations are due to genetic anomalies. Patterns of autosomal dominant, autosomal recessive and X-linked inheritance have been described. Mitochondrial inheritance and chromosomal anomalies can also be responsible for congenital heart malformations. Several genes for congenital heart defects have been identified. We review current knowledge on the genetic etiology of congenital heart disease.
authors.affiliation: Servicio de Genética, Hospital 12 de Octubre, Madrid. mmoreno@tdi.es
authors.forename: M
authors.initials: M
authors.lastname: Moreno García
authors.forename: M J
authors.initials: MJ
authors.lastname: Gómez Rodríguez
authors.forename: E
authors.initials: E
authors.lastname: Barreiro Miranda
mesh_terms: D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D005817:Genetic Counseling; D006330:Heart Defects, Congenital / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D017240:Mitochondrial Myopathies / Q000235:genetics