Post-streptococcal uveitis.
BACKGROUND
We report additional evidence supporting the association between the occurrence of bilateral nongranulomatous uveitis and previous infection by group A streptococci--i.e., post-streptococcal syndrome.


METHODS
As shown through a series of case reports, physical examination and laboratory blood analysis--including antistreptolysin O (ASO) antibody titer--were ordered due to a recent history of sore throat and presence of nongranulomatous bilateral anterior uveitis.


RESULTS
Serological laboratory testing revealed elevated ASO antibody titer. The etiology of the uveitis was attributed to streptococcal infection. Bilateral uveitis responded to topical corticosteroids. Systemic antibiotic treatment was used to treat possible post-streptococcal syndrome sequelae with resolution of symptoms.


CONCLUSIONS
Uveitis should be considered a possible manifestation of post-streptococcal syndrome. ASO antibody quantification should be included in the serologic testing performed in evaluating the cause of seemingly idiopathic bilateral nongranulomatous anterior uveitis associated with signs and symptoms that suggest previous streptococcal infection.
Besada
E
E
Nova Southeastern University, College of Optometry, Ft. Lauderdale, Florida, USA.
Schatz
S
S
Saremi
S S
SS
D000293:Adolescent; D000900:Anti-Bacterial Agents; D000989:Antistreptolysin / Q000032:analysis; D002648:Child; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D013290:Streptococcal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D013291:Streptococcus / Q000276:immunology; D014606:Uveitis, Anterior / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D000989:Antistreptolysin