title: Effect of dietary supplementation with sea buckthorn (Hippophaë rhamnoides) seed and pulp oils on the fatty acid composition of skin glycerophospholipids of patients with atopic dermatitis.
abstract: Sea buckthorn (Hippophaë rhamnoides) seed and pulp oils have traditionally been used for treating skin diseases in China and Russia, but are not widely used in other countries. A placebo-controlled, parallel study was carried out to investigate the effects of these oils on the fatty acid composition of skin glycerophospholipids of patients with atopic dermatitis. Sixteen patients ate 5 g of sea buckthorn seed oil, pulp oil, or paraffin oil daily for 4 months. Skin fatty acids were analyzed with gas chromatography before and after treatment. The seed oil slightly increased the proportion of docosapentaenoic acid (22:5n-3) and decreased the proportion of palmitic acid (16:0) in skin glycerophospholipids (0.05 < P < 0.1). The levels of the other fatty acids remained stable. The results show that the fatty acid composition of skin glycerophospholipids is well buffered against short-term dietary modification.
authors.affiliation: Department of Biochemistry and Food Chemistry, University of Turku, Turku, Finland.
authors.forename: B
authors.initials: B
authors.lastname: Yang
authors.forename: K O
authors.initials: KO
authors.lastname: Kalimo
authors.forename: R L
authors.initials: RL
authors.lastname: Tahvonen
authors.forename: L M
authors.initials: LM
authors.lastname: Mattila
authors.forename: J K
authors.initials: JK
authors.lastname: Katajisto
authors.forename: H P
authors.initials: HP
authors.lastname: Kallio