Effects of growth hormone treatment on visceral adipose tissue.
It is now evident that an increased amount of intra-abdominal (visceral) adipose tissue is associated with an impaired metabolic profile, increasing the risk of CVD and NIDDM. Visceral obesity also appears to be associated with impaired GH action. GH replacement therapy in patients with GHD, or GH treatment of viscerally obese individuals, is able to induce a profound reduction in the amount of visceral adipose tissue and to improve the metabolic profile.
Brummer
R J
RJ
Department of Internal Medicine, University Hospital Maastricht, The Netherlands.
D015502:Absorptiometry, Photon; D000172:Acromegaly / Q000188:drug therapy; D000273:Adipose Tissue / Q000000981:diagnostic imaging / Q000187:drug effects*; D000886:Anthropometry; D002986:Clinical Trials as Topic; D004393:Dwarfism, Pituitary / Q000188:drug therapy; D020249:Hormone Replacement Therapy; D019382:Human Growth Hormone / Q000172:deficiency / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
D019382:Human Growth Hormone