Exposure to strong ELF magnetic fields does not alter cardiac autonomic control mechanisms.
Clinical and epidemiological studies attest that alterations in heart rate variability (HRV) are predictive of specific types of cardiovascular morbidity and mortality in otherwise healthy persons. Recent reports also suggest that changes in HRV may be associated with exposure to intermittent magnetic fields (60 Hz, 28.3 microT) in the laboratory and that mortality is increased in cardiac disease categories related to altered HRV for utility workers whose jobs involve longer exposure to elevated magnetic fields. This study combined three approaches to learn more about the specific exposure circumstances under which changes in HRV occur. First, cardiac autonomic control, as indexed by HRV spectral analysis measures, was measured in 24 men during exposure to a much higher intensity field than any previously examined (resultant flux density = 127.3 microT [1273 milliGauss, mG]). Second, HRV measures from the same individual were compared across three relevant test conditions: intermittent and continuous field exposure and during a no-exposure, control condition. Third, electrocardiographic data were analyzed to determine if the precise timing of when the magnetic field switched on or off in relation to the cardiac cycle results in phase-resetting of the human cardiac rhythm. HRV measures were not altered by either field exposure condition compared to the control condition, and no evidence for a phase-resetting mechanism was found. Further research is needed to resolve the differences between the present and the earlier laboratory-based studies of HRV and to determine if cardiac rhythm disturbances are associated with exposure to the more complex magnetic fields found in the man-made environment.
Graham
C
C
Midwest Research Institute, Kansas City, MO 64110, USA. cgraham@mriresearch.org
Sastre
A
A
Cook
M R
MR
Kavet
R
R
Gerkovich
M M
MM
Riffle
D W
DW
D000328:Adult; D000704:Analysis of Variance; D001341:Autonomic Nervous System / Q000528:radiation effects*; D018592:Cross-Over Studies; D004311:Double-Blind Method; D015716:Electrocardiography, Ambulatory / Q000528:radiation effects; D004574:Electromagnetic Fields / Q000009:adverse effects*; D004781:Environmental Exposure; D005583:Fourier Analysis; D006329:Heart Conduction System / Q000528:radiation effects*; D006339:Heart Rate / Q000528:radiation effects; D006801:Humans; D016014:Linear Models; D008297:Male; D016273:Occupational Exposure; D012815:Signal Processing, Computer-Assisted