title: Air-bone gap and resonant frequency in large vestibular aqueduct syndrome.
abstract: BACKGROUND
  Conductive hearing loss is occasionally recognized in large vestibular aqueduct (LVA) syndrome; however, the incidence rate and the cause are not known.
  
  
  OBJECTIVE
  To compare air and bone conduction levels between patients with LVA syndrome and those with idiopathic sudden sensorineural hearing loss, and to investigate the cause of the air-bone gap.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  The patients were treated at a tertiary referral center.
  
  
  METHODS
  Twenty-eight ears of 15 patients with LVA syndrome and 28 ears of patients with idiopathic sudden sensorineural hearing loss were examined. The latter patients were selected from a computerized database to match the former patients in air conduction levels.
  
  
  METHODS
  Pure-tone audiometry, multiple frequency tympanometry, acoustic reflex, otoacoustic emission, vestibular evoked myogenic response.
  
  
  RESULTS
  The air-bone gap in patients with LVA syndrome was always larger than that in patients with idiopathic sudden sensorineural hearing loss with the same air conduction level. The resonant frequency in patients with LVA syndrome was rather low compared with that in normal control subjects, in contrast to the finding that resonant frequency was significantly high in patients with otosclerosis.
  
  
  CONCLUSIONS
  An air-bone gap exists to some degree in almost all patients with LVA syndrome. The air-bone gap may not be associated with the movement restriction of the stapes as it is with otosclerosis.
authors.affiliation: Department of Otorhinolaryngology, Nagoya University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nakashima
authors.forename: H
authors.initials: H
authors.lastname: Ueda
authors.forename: A
authors.initials: A
authors.lastname: Furuhashi
authors.forename: E
authors.initials: E
authors.lastname: Sato
authors.forename: K
authors.initials: K
authors.lastname: Asahi
authors.forename: S
authors.initials: S
authors.lastname: Naganawa
authors.forename: R
authors.initials: R
authors.lastname: Beppu
mesh_terms: D000158:Acoustic Impedance Tests; D000293:Adolescent; D000328:Adult; D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold / Q000502:physiology; D001844:Bone Conduction / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D006314:Hearing Loss, Conductive / Q000175:diagnosis* / Q000209:etiology*; D003639:Hearing Loss, Sudden / Q000175:diagnosis*; D006801:Humans; D008297:Male; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology; D012022:Reflex, Acoustic / Q000502:physiology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013577:Syndrome; D014717:Vertigo / Q000175:diagnosis; D014723:Vestibular Aqueduct / Q000002:abnormalities*