Palladium-catalyzed synthesis of aqueous, fluorous, and supercritical CO2-soluble phosphines
[reaction: see text]A generic, simple, and economical route has been developed for the synthesis of phosphines soluble in aqueous, fluorous, and supercritical CO2 phases. The methodology is based on the palladium-catalyzed Heck olefination of haloarylphosphine oxides followed by reduction, affording various arylphosphines in high yields.
Chen
W
Department of Chemistry, University of Liverpool, UK.
Xu
L
Xiao
J