Morphometric analysis of the human ophthalmic nerve and the aging process.
In the present study, the morphometric changes that occur in the human ophthalmic nerve fibers during the aging process were analyzed with the use of new discriminative staining method, which permits simultaneous observation of the axon and surrounding myelin sheath. Morphometric data on axons were collected in 45 human cadavers. A significant reversed correlation was observed between those data and the age of the subject. Our results indicate that definite changes occur in the ophthalmic nerve during the aging process.
Duan
J
J
Department of Anatomy, Showa University School of Medicine, Tokyo, Japan.
Goto
N
N
Moriyama
H
H
Nonaka
N
N
Lu
S
S
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009882:Ophthalmic Nerve / Q000166:cytology*; D013194:Staining and Labeling / Q000379:methods