title: Prions and neurodegenerative diseases.
abstract: The long-term, progressive decay of the central nervous system typifies prion diseases, a group of rare, transmissible maladies affecting humans, sheep, cattle and some other types of mammal. Little is known about the early molecular events in its pathogenesis but the diverse roles of PrP, the prion protein, in its destructive action have recently been re-emphasised.
authors.affiliation: Institute for Animal Health, Berkshire RG20 7NN, Compton, UK. james.hope@bbsrc.ac.uk
authors.forename: J
authors.initials: J
authors.lastname: Hope
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D006801:Humans; D017096:Prion Diseases / Q000235:genetics*; D011328:Prions / Q000235:genetics*
chemical_list: D011328:Prions