title: A new anti-HIV triterpene from Geum japonicum.
abstract: Geumonoid (1), a new triterpene, was isolated from Geum japonicum. Its structure was elucidated on the basis of 1D, 2D NMR and MS spectroscopic analysis. Compound 1 showed inhibitory activity against HIV-1 protease.
authors.affiliation: Department of Biology and Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, NT.
authors.forename: H X
authors.initials: HX
authors.lastname: Xu
authors.forename: D S
authors.initials: DS
authors.lastname: Ming
authors.forename: H
authors.initials: H
authors.lastname: Dong
authors.forename: P P
authors.initials: PP
authors.lastname: But
mesh_terms: D019380:Anti-HIV Agents / Q000302:isolation & purification* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology; D017320:HIV Protease Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology; D015497:HIV-1 / Q000187:drug effects / Q000201:enzymology*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D019380:Anti-HIV Agents; D017320:HIV Protease Inhibitors; D014315:Triterpenes; C419245:geumonoid