Cognitive performance in surgically menopausal women on estrogen.
Estrogen replacement therapy (ERT) may help maintain normal cognitive function. Nondemented surgically menopausal women on ERT (n = 10) enrolled in a longitudinal aging study performed better than age- and education-matched control subjects (n = 25) on selected tests of verbal memory and constructional ability. These results suggest that ERT initiated soon after surgical menopause can have long-term neuroprotective effects in cognitively intact women.
Verghese
J
J
Einstein Aging Study , Albert Einstein College of Medicine, Bronx, NY 10461, USA. joev3@idt.net
Kuslansky
G
G
Katz
M J
MJ
Sliwinski
M
M
Crystal
H A
HA
Buschke
H
H
Lipton
R B
RB
D000368:Aged; D003071:Cognition / Q000187:drug effects*; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008594:Menopause, Premature / Q000187:drug effects* / Q000523:psychology*; D009483:Neuropsychological Tests