title: Evaluation of four blood pump geometries: the optical tracer technique.
abstract: Artificial blood pump assistance of the failing human heart can allow it to recover. Analysis of blood pump fluid flow is a useful tool for design development and thrombosis minimization. The aim of this study was to investigate fluid flow, particularly ventricular clearance rate and stagnation areas, in four different blood pump geometries and to determine the best design. The blood pumps consisted of a polyurethane ventricle, and combinations of inlet/outlet pipe angles and compression plate shapes. A video camera recorded the motion of fluid labelled with an optical tracer (Methyl Blue histological dye). A novel processing method was developed to produce colour maps of tracer concentration, experimentally calibrated. An overall picture of fluid flow in each pump geometry was generated by considering clearance curves, tracer concentration maps and inflow jet animations. Overall and local mixing coefficients are calculated for each pump. The best geometry featured straight inlet/outlet pipes and a domed compression plate. This optical tracer technique has proven convenient, economical, sensitive to low concentrations of tracer and provides instantaneous pictures of tracer distribution in a ventricle.
authors.affiliation: University Department of Cardiac Surgery, Glasgow Royal Infirmary, Scotland, UK.
authors.forename: M L
authors.initials: ML
authors.lastname: Rose
authors.forename: T G
authors.initials: TG
authors.lastname: Mackay
authors.forename: W
authors.initials: W
authors.lastname: Martin
authors.forename: D J
authors.initials: DJ
authors.lastname: Wheatley
mesh_terms: D001557:Benzenesulfonates; D002138:Calibration; D004395:Dye Dilution Technique / Q000706:statistics & numerical data; D004867:Equipment Design / Q000706:statistics & numerical data; D005069:Evaluation Studies as Topic; D006353:Heart-Assist Devices / Q000706:statistics & numerical data; D006801:Humans; D011140:Polyurethanes; D012212:Rheology / Q000379:methods / Q000706:statistics & numerical data; D013997:Time Factors
chemical_list: D001557:Benzenesulfonates; D011140:Polyurethanes; C414357:Methyl Blue