Identification and targeting policies for computer-controlled infusion pumps.
In this article a series of useful techniques is presented to improve the adaptation capabilities of computer-controlled infusion pumps: an identification algorithm for the time constant of the effect compartment, a smoothing technique for estimation based on noisy data, and an infusion policy to target any effect site concentration with no overshoot.
Gentilini
A
A
ETH Zürich, Institut für Automatik, Switzerland.
Frei
C W
CW
Glattfelder
A H
AH
Morari
M
M
Schnider
T W
TW
D000465:Algorithms; D001499:Bayes Theorem; D007260:Infusion Pumps; D010599:Pharmacokinetics; D013813:Therapy, Computer-Assisted / Q000379:methods*