title: The frequency of histologically dysplastic nevi in 199 pediatric patients.
abstract: Many uncertainties surround the definition, frequency, and significance of dysplastic nevi in children. Consequently the management of dysplastic nevi in the pediatric population has been largely derived from the studies of adults. Biopsies are usually performed on this young age group because of lesion change or abnormal appearance. One might therefore assume that the frequency of histologically diagnosed dysplastic nevi would be higher in children than in adults. We decided to attempt to verify this assumption by determining the frequency of dysplastic nevi diagnosed histologically in the pediatric population. To do this we reviewed 199 cutaneous pathology reports of nevi removed from patients less than 18 years old and submitted to a community-based dermatopathology laboratory. The diagnosis of dysplastic nevus was made based on histologic criteria recommended by the World Health Organization Melanoma Program. We found that 3 of 199 nevi submitted for histologic analysis met the histologic criteria for dysplastic nevus. There were no melanomas. Our data suggest that there is an extremely low frequency of histologically confirmed dysplastic nevi within the general pediatric population.
authors.affiliation: Department of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Haley
authors.forename: A F
authors.initials: AF
authors.lastname: Hood
authors.forename: T Y
authors.initials: TY
authors.lastname: Chuang
authors.forename: J
authors.initials: J
authors.lastname: Rasmussen
mesh_terms: D000293:Adolescent; D002648:Child; D003937:Diagnosis, Differential; D004416:Dysplastic Nevus Syndrome / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*