title: Myoepithelial carcinoma of the lung arising from bronchial submucosa.
abstract: Myoepithelial neoplasm mainly occurs in the salivary glands and breasts and is extremely rare in the lung. To our knowledge, this report describes the first documented case of a myoepithelial carcinoma present in the lung. The tumor derived from the right main bronchial submucosa and exhibited a dual epithelial and smooth muscular phenotype by immunohistochemical and ultrastructural studies. It invaded the neighboring pulmonary tissue and the hilar lymph nodes. Despite a right pneumonectomy and chemotherapy, metastasis was found in the left lung 7 months later.
authors.affiliation: Division of Pathology, Hamamatsu University School of Medicine, Japan. kmiura@hama-med.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Miura
authors.forename: H
authors.initials: H
authors.lastname: Harada
authors.forename: S
authors.initials: S
authors.lastname: Aiba
authors.forename: Y
authors.initials: Y
authors.lastname: Tsutsui
mesh_terms: D001984:Bronchial Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000556:secondary / Q000648:ultrastructure; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009208:Myoepithelioma / Q000473:pathology* / Q000648:ultrastructure; D009361:Neoplasm Invasiveness; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000648:ultrastructure