title: Proteomics: applications in basic and applied biology.
abstract: The rapid evolution of proteomics has continued during the past year, with a series of innovations in the core technologies of two-dimensional electrophoresis and mass spectrometry, and a diversity of productive research programmes. Well-annotated proteomics databases are now emerging in a number of fields to provide a platform for systematic research, with particularly promising progress in clinical applications such as cardiology and oncology. Large-scale quantitative research, comparable in power and sensitivity to that achieved for gene expression, is thus becoming a reality at the protein level.
authors.affiliation: Large Scale Proteomics Corporation, Rockville, MD 20850, USA.
authors.forename: N L
authors.initials: NL
authors.lastname: Anderson
authors.forename: A D
authors.initials: AD
authors.lastname: Matheson
authors.forename: S
authors.initials: S
authors.lastname: Steiner
mesh_terms: D016208:Databases, Factual; D015180:Electrophoresis, Gel, Two-Dimensional / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods; D008511:Medicine; D008967:Molecular Biology / Q000379:methods* / Q000639:trends; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D014116:Toxicology / Q000639:trends
chemical_list: D011506:Proteins