Dexmedetomidine--a novel sedative for postoperative sedation.
Dexmedetomidine is new sedative being developed for use in postoperative sedation in ICU. It acts at a 2 adrenoceptors to produce sedation, anxiolysis and analgesia. Patients remain easily rousable and do not suffer significant respiratory depression, consequently dexmedetomidine may be continued post extubation.
Bradley
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St. George's Hospital, London, UK.
D000316:Adrenergic alpha-Agonists / Q000494:pharmacology / Q000627:therapeutic use*; D016292:Procedural Sedation / Q000379:methods* / Q000451:nursing; D020927:Dexmedetomidine / Q000494:pharmacology / Q000627:therapeutic use*; D016903:Drug Monitoring / Q000379:methods / Q000451:nursing; D011307:Drug Prescriptions; D004335:Drug and Narcotic Control; D005060:Europe; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology / Q000627:therapeutic use*; D011182:Postoperative Care / Q000379:methods* / Q000451:nursing
D000316:Adrenergic alpha-Agonists; D006993:Hypnotics and Sedatives; D020927:Dexmedetomidine