Role of intravenous ultrasound contrast in stress echocardiography.
Intravenous newer generation perfluorocarbon containing microbubbles have been shown to enhance endocardial borders, especially during harmonic imaging. Although this significantly improves the detection of wall-motion abnormalities during stress echocardiography, intermittent imaging consistently results in myocardial contrast following intravenous infusions or injections of perfluorocarbon microbubbles. Detection of myocardial perfusion abnormalities during both exercise and pharmacologic stress echocardiography appears to be feasible clinically with either intravenous injections or continuous infusions of microbubbles using intermittent harmonic imaging. Accelerated intermittent harmonic imaging allows one to rapidly acquire both myocardial perfusion and wall motion during exercise and dobutamine stress echocardiography.
Porter
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University of Nebraska Medical Center, 981165 Nebraska Medical Center, Omaha, NE 68198-1165, USA.
D002316:Cardiotonic Agents / Q000008:administration & dosage; D003287:Contrast Media / Q000008:administration & dosage*; D003326:Coronary Circulation / Q000187:drug effects / Q000502:physiology; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D004452:Echocardiography / Q000379:methods*; D005080:Exercise Test; D005240:Feasibility Studies; D005466:Fluorocarbons / Q000008:administration & dosage; D006801:Humans; D007275:Injections, Intravenous; D009200:Myocardial Contraction / Q000187:drug effects / Q000502:physiology; D015203:Reproducibility of Results
D002316:Cardiotonic Agents; D003287:Contrast Media; D005466:Fluorocarbons