Synthesis of [1]benzopyrano[2,3,4-kl]acridin-3-ol and its analogues as pentacyclic compounds.
A new heterocyclic compound, [1]benzopyrano[2,3,4-kl]acridin-3-ol was synthesized by cyclization of xanthone derivatives. The key compound, 1-(3'-methoxyanilino)-xanthone, was prepared from 1-aminoxanthone. [1]benzopyrano[2,3,4-kl]acridin-3-ol analogues, [1]benzothiopyrano[2,3,4-kl]acridin-3-ol, pyrido[3',2':5,6]pyrano[2,3,4-kl]acridin-3-ol and pyrido[3',2':5,6]thiopyrano[2,3,4-kl]acridin-3-ol were synthesized by the same method.
Fujiwara
H
H
Niigata College of Pharmacy, Japan. fujiwara@niigata-pharm.ac.jp
Kitagawa
K
K
D000166:Acridines / Q000138:chemical synthesis*; D001578:Benzopyrans / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D017550:Spectroscopy, Fourier Transform Infrared
C419249:(1)benzopyrano(2,3,4-kl)acridin-3-ol; D000166:Acridines; D001578:Benzopyrans; D007202:Indicators and Reagents