Synthesis and evaluation of antimitotic activity of alkylated 2-amino-1,3,4-oxadiazole derivatives.
Series of N-alkylated-2-amino-1,3,4-oxadiazoles (2) were synthesized via alkylation of 2-amino-1,3,4-oxadiazoles (1) under phase transfer condition. This paper also describes the study of antimitotic activity of these molecules by onion root tip method.
Rai
K M
KM
Department of Studies in Chemistry, University of Mysore, Manasagangothri, India. kmlrai@yahoo.com
Linganna
N
N
D000478:Alkylation; D008938:Mitosis / Q000187:drug effects*; D019697:Onions; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots / Q000166:cytology / Q000187:drug effects; D013057:Spectrum Analysis
D010069:Oxadiazoles