Caspases as targets for anti-inflammatory and anti-apoptotic drug discovery.
Talanian
R V
RV
BASF Bioresearch Corporation, 100 Research Drive, Worcester, Massachusetts 01605, USA. talanir@BASF.com
Brady
K D
KD
Cryns
V L
VL
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects*; D020170:Caspase 1 / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D020169:Caspases / Q000737:chemistry / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D015853:Cysteine Proteinase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D016207:Cytokines / Q000378:metabolism; D015195:Drug Design; D006801:Humans; D015398:Signal Transduction; D013379:Substrate Specificity
D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D015853:Cysteine Proteinase Inhibitors; D016207:Cytokines; D020169:Caspases; D020170:Caspase 1