Immunocytochemical localization of lung-type prostaglandin F synthase in the rat spinal cord.
Prostaglandin F synthase, producing prostaglandin F(2 alpha) and 9 alpha,11 beta-prostaglandin F(2), has at least two isozymes, lung-type and liver-type ones. The present study including double immunolabelling with microtubule-associated protein 2 indicated that the lung-type isozyme was present in neuronal dendrites and somata of gray matter (relatively intense in lamina I and II in dorsal horn, and IX in ventral horn) and vascular endothelial cells in the rat spinal cord at all segmental levels.
Suzuki-Yamamoto
T
T
Department of Anatomy and Cell Biology, School of Medicine, The University of Tokushima, Kuramoto, Tokushima 770-8503, Japan.
Toida
K
K
Tsuruo
Y
Y
Watanabe
K
K
Ishimura
K
K
D000818:Animals; D003712:Dendrites / Q000201:enzymology / Q000648:ultrastructure; D004730:Endothelium, Vascular / Q000201:enzymology / Q000648:ultrastructure; D006911:Hydroxyprostaglandin Dehydrogenases / Q000378:metabolism*; D007527:Isoenzymes / Q000378:metabolism*; D008168:Lung / Q000201:enzymology*; D009474:Neurons / Q000201:enzymology* / Q000648:ultrastructure; D051381:Rats; D013116:Spinal Cord / Q000201:enzymology* / Q000648:ultrastructure
D007527:Isoenzymes; D006911:Hydroxyprostaglandin Dehydrogenases; C031051:prostaglandin-F synthase