title: The spectrum of Sertoli cell tumors in children.
abstract: The spectrum of Sertoli cell tumors in children covers a wide range of testis and ovarian tumors classified as sex cord-stromal tumors. Sertoli cell tumor of the testis is extremely rare in the pediatric population. The American Academy of Pediatrics Section on Urology Prepubertal Testicular Tumor Registry has reported a total of six cases of Sertoli cell tumor of the testis, accounting for 1.3% of the 430 cases reported to the registry as of October 1996. Despite their rarity, Sertoli cell variants of sex cord-stromal tumors have generated keen interest because of their variable histologic appearance and biologic behavior, including endocrine activity. Because sex cord-stromal tumors occur in the ovary and testis, a primitive cellular origin to these tumors is likely in males and females.
authors.affiliation: Department of Urology, Children's Hospital, Boston, Massachusetts, USA. borer_j@A1.tch.harvard.edu
authors.forename: J G
authors.initials: JG
authors.lastname: Borer
authors.forename: P E
authors.initials: PE
authors.lastname: Tan
authors.forename: D A
authors.initials: DA
authors.lastname: Diamond
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D010051:Ovarian Neoplasms / Q000473:pathology*; D012707:Sertoli Cell Tumor / Q000473:pathology*; D018312:Sex Cord-Gonadal Stromal Tumors / Q000473:pathology; D013736:Testicular Neoplasms / Q000473:pathology*