title: [The symptomatic patient with pathologic coronary angiogram. "evidence-based" or "best-evidence medicine" in the interventional cardiology].
abstract: Ischemic heart disease is the most frequent cause of death in industrialized countries. This is a result of persistent risk factors and aging of the population. Medical progress with application of conservative, surgical or interventional strategies indeed reduced the morbidity and mortality of arteriosclerotic diseases, but markedly increased the medical care costs. The result is a discussion about the optimal use of the different therapeutic measures under consideration of the evidence based medicine. This article reviews several recently published clinical trials and discusses, which patient with symptomatic coronary artery disease should undergo a conservative strategy, percutaneous or surgical revascularization.
authors.affiliation: Medizinische Klinik I, Klinikum Krefeld.
authors.forename: O
authors.initials: O
authors.lastname: Volk
authors.forename: F
authors.initials: F
authors.lastname: Späh
authors.forename: H G
authors.initials: HG
authors.lastname: Klues
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000188:drug therapy / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D019317:Evidence-Based Medicine; D005500:Follow-Up Studies; D006801:Humans; D015201:Meta-Analysis as Topic; D008875:Middle Aged; D009204:Myocardial Revascularization; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D015607:Stents; D013997:Time Factors
chemical_list: D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors