Stereocontrolled synthesis of the 22E,24 beta(S)-trifluoromethyl steroidal side chain and its application to the synthesis of fluorinated analogues of naturally occurring sterols.
Jiang
B
B
Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, Peoples Republic of China. jiangb@pub.sioc.ac.cn
Liu
Y
Y
Zhou
W
W
D018360:Crystallography, X-Ray; D003500:Cyclization; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013237:Stereoisomerism; D013259:Steroids, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D013261:Sterols / Q000138:chemical synthesis* / Q000737:chemistry
D007202:Indicators and Reagents; D013259:Steroids, Fluorinated; D013261:Sterols