Formation of supported membranes from vesicles.
Using a combination of the quartz crystal microbalance and surface plasmon resonance techniques, we have studied the spontaneous formation of supported lipid bilayers from small (approximately 25 nm) unilamellar vesicles. Together these experimental methods measure the amount of lipid adsorbed on the surface and the amount of water trapped by the lipid. With this approach, we have, for the first time, been able to observe in detail the progression from the adsorption of intact vesicles to rupture and bilayer formation. Monte Carlo simulations reproduce the data.
Keller
C A
CA
Department of Applied Physics, Chalmers University of Technology, S-412 96 Göteborg, Sweden.
Glasmästar
K
K
Zhdanov
V P
VP
Kasemo
B
B
D000327:Adsorption; D008051:Lipid Bilayers / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry*; D009010:Monte Carlo Method; D020349:Surface Plasmon Resonance; D013499:Surface Properties; D013997:Time Factors; D014867:Water / Q000737:chemistry
D008051:Lipid Bilayers; D008081:Liposomes; D014867:Water