TMC-135A and B, new triene-ansamycins, produced by Streptomyces sp.
Nishio
M
M
Discovery Research Laboratory, Tanabe Seiyaku Co., Ltd., Toda-shi, Saitama, Japan.
Kohno
J
J
Sakurai
M
M
Suzuki
S I
SI
Okada
N
N
Kawano
K
K
Komatsubara
S
S
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D004354:Drug Screening Assays, Antitumor; D005285:Fermentation; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D015394:Molecular Structure; D017828:Rifabutin / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013302:Streptomyces / Q000145:classification / Q000378:metabolism*; D013329:Structure-Activity Relationship; D014407:Tumor Cells, Cultured
D000903:Antibiotics, Antineoplastic; C414188:TMC-135A; C414187:TMC-135B; D017828:Rifabutin