title: Y chromosomal short tandem repeat (STR) loci in a representative group of males living in South Württemberg: a database for application in forensic medicine.
abstract: In this study, we resolved the allelic distribution of three Y chromosomal short tandem repeats (STRs), DYS19 (n=218), DYS390 (n=257) and DYS393 (n=215), in a population study of 257 unrelated men living in the area of South Wüerttemberg/Hohenzollern. In DYS19 and in DYS393, five different alleles were discovered, and in DYS390, six different alleles. Forty-nine different haplotypes were found in 202 unrelated male individuals. By investigating each of the three STR systems separately, the most powerful results were found in DYS390, with a PE (power of exclusion) of 0.74, followed by DYS19 (PE: 0.65) and DYS393 (PE: 0.47). Using a combination of two systems (n=202), the PEs ranged from 0.79 (DYS19 and DYS393) to 0.89 (DYS19 and DYS390). The combination of all three STR systems revealed a PE of 0.93.
authors.affiliation: Institute of Forensic Medicine, University of Tuebingen, Naegelestrasse 5, D-72074, Tuebingen, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Graw
authors.forename: T
authors.initials: T
authors.lastname: Seitz
mesh_terms: D016172:DNA Fingerprinting / Q000379:methods*; D016208:Databases, Factual; D005787:Gene Frequency / Q000235:genetics*; D005858:Germany; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D008297:Male; D018598:Minisatellite Repeats / Q000235:genetics*; D010334:Paternity; D012494:Sampling Studies; D014998:Y Chromosome / Q000235:genetics*