title: Resistance patterns of urinary tract infections diagnosed in a genitourinary medicine clinic.
abstract: We aimed to assess the prevalence of antibiotic resistance amongst urinary tract isolates within our clinic. Local protocol has been to prescribe a 3-day course of trimethoprim for uncomplicated urinary tract infections (UTIs). Notes of all culture-proven UTIs (October 1998 to September 1999) were examined. Eighty-six urinary isolates were identified in 84 patients. Seventy-three of the isolates were coliforms with 46 being Escherichia coli. Of the 86 urinary isolates 28 (32.6%) were resistant to trimethoprim, 37 (43.5%) to amoxycillin, 5 (5.8%) to cephradine and 3 (3.5%) to nitrofurantoin. Seventy-four (86%) of the UTIs were known to have been treated; 41 at initial presentation and 33 once sensitivities were available. Of the 41 patients who received treatment initially, 11 needed to return to the clinic for a further course of antibiotics. To try and reduce the number of inappropriate treatments and unnecessary visits a number of options regarding clinic protocol were explored.
authors.affiliation: Department of Genitourinary Medicine, Mayday University Hospital, London, UK.
authors.forename: A
authors.initials: A
authors.lastname: Newell
authors.forename: P
authors.initials: P
authors.lastname: Riley
authors.forename: M
authors.initials: M
authors.lastname: Rodgers
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000554:Ambulatory Care Facilities / Q000706:statistics & numerical data*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002985:Clinical Protocols; D004352:Drug Resistance, Microbial; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D004927:Escherichia coli Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D018579:Patient Selection; D015995:Prevalence; D012189:Retrospective Studies; D016896:Treatment Outcome; D014552:Urinary Tract Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents