[Resistance testing in general practice--is it valid?].
Resistance of uropathogenic bacteria to antibiotics is an increasing problem in primary health care. The aim of this study was to evaluate antibacterial susceptibility testing of uropathogenic when performed in general practice. Urine specimens with a known quantity of typically uropathogenic bacteria were sent to 25 general practices. The predictive values of testing a bacterial strain as susceptible ranged from 0.89 (nitrofurantoin) to 1.00 (sulphamethizole), and the predictive value of testing a bacterial strain as resistant ranged from 0.55 (trimethoprim) to 0.90 (nitrofurantoin). If susceptibility testing is to be widely implemented in general practice it would be necessary to improve the validity.
Bjerrum
L
L
Forskningsenheden for Almen Medicin, Syddansk Universitet, Odense. l-bjerrum@win-chs.ou.dk
Grinsted
P
P
Petersen
P H
PH
Søgaard
P
P
D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000009:adverse effects; D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage* / Q000009:adverse effects; D001437:Bacteriuria / Q000188:drug therapy / Q000382:microbiology; D003718:Denmark; D004352:Drug Resistance, Microbial; D005194:Family Practice / Q000592:standards*; D006801:Humans; D007202:Indicators and Reagents; D008826:Microbial Sensitivity Tests / Q000592:standards*; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000382:microbiology
D000900:Anti-Bacterial Agents; D000892:Anti-Infective Agents, Urinary; D007202:Indicators and Reagents