Double infection with a resistant and a multidrug-resistant strain of Mycobacterium tuberculosis.
An immunocompetent patient was dually infected with a resistant and a multidrug-resistant strain of Mycobacterium tuberculosis (TB). The multidrug-resistant strain, which belongs to the W- strain/Beijing family, was first isolated after 3 months of therapy. Inappropriate treatment led to further drug resistance and unsuccessful therapy. Thus, additional infections with resistant M. tuberculosis strains should be considered when tuberculosis therapy fails.
Niemann
S
S
Forschungszentrum Borstel, National Reference Center for Mycobacteria, Borstel, Germany.
Richter
E
E
Rüsch-Gerdes
S
S
Schlaak
M
M
Greinert
U
U
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D018432:Drug Resistance, Multiple; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D017211:Treatment Failure; D014374:Tuberculin Test; D014376:Tuberculosis / Q000188:drug therapy*
D000995:Antitubercular Agents