Intraepithelial carcinoma of the oesophagus: report of 25 cases from north-east Italy.
OBJECTIVE
To investigate the incidence and define the diagnostic aspects of intraepithelial squamous cell carcinoma of the oesophagus and to show the trend in its natural history.


METHODS
Analysis of records of more than 31000 upper gastrointestinal endoscopies in a secondary referral centre.


METHODS
Gastroenterology unit, Italy.


METHODS
23 men and 2 women with endoscopic and histological diagnoses of intraepithelial squamous cell carcinoma of the oesophagus.


RESULTS
The incidence was 0.8/1000 patients/year. There was a coexisting oropharyngeal or laryngeal cancer in 17 patients. The endoscopic appearance was of a more or less well-defined hyperaemic area. Lesions progressed to infiltrating carcinoma in a mean of 18.3 months range 11-32).


CONCLUSIONS
Intraepithelial squamous cell carcinoma is rare in this population. Endoscopy and histology are essential for diagnosis and staging.
Benedetti
G
G
Gastroenterology Unit, Santa Maria degli Angeli Hospital, Pordenone, Italy.
Sablich
R
R
Vitalba
A
A
Lacchin
T
T
Guido
E
E
Del Bianco
T
T
D000328:Adult; D000368:Aged; D002278:Carcinoma in Situ / Q000453:epidemiology* / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D004938:Esophageal Neoplasms / Q000453:epidemiology* / Q000473:pathology; D004947:Esophagus / Q000473:pathology; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging