Adipose tissue as an endocrine organ.
The objective is to present a brief overview of peptide and non-peptide factors secreted from adipocytes and to describe some studies on the postulated role of the locally active triad angiotensinogen/angiotensinII/ prostacyclin in the development/enlargement of adipose tissue mass and increased blood pressure. In addition to the role of adipose tissue as an endocrine organ, the results emphasize the autocrine/paracrine mechanisms which are postulated to play a role in adipose tissue development and enlargement.
Ailhaud
G
G
Laboratoire de Biologie du Développement du Tissu Adipeux, Centre de Biochimie, UNSA, Faculté des Sciences, Nice, France. ailhaud@unice.fr
D000273:Adipose Tissue / Q000502:physiology*; D000804:Angiotensin II / Q000502:physiology; D000808:Angiotensinogen / Q000502:physiology; D004702:Endocrine Glands / Q000502:physiology*; D011464:Epoprostenol / Q000502:physiology; D004967:Estrogens / Q000378:metabolism; D005260:Female; D012739:Gonadal Steroid Hormones / Q000502:physiology; D006801:Humans; D050356:Lipid Metabolism; D008297:Male
D004967:Estrogens; D012739:Gonadal Steroid Hormones; D000808:Angiotensinogen; D000804:Angiotensin II; D011464:Epoprostenol