title: Alcohol and behavioral control: impaired response inhibition and flexibility in social drinkers.
abstract: This study shows that a moderate dose of alcohol (0.62 g/kg) can impair cognitive processes controlling behavioral inhibition and flexibility (i.e., inhibiting one response and making a different one). Two groups of male social drinkers (n = 8) received alcohol or a placebo and performed two change tasks that required high or low information processing. Results showed that alcohol impaired inhibitory control and response flexibility following a failure to inhibit a first response, and the intensity of impairment did not differ under the two information processing conditions. Response reaction time and accuracy were not affected by alcohol. These findings indicate that alcohol can impair some cognitive aspects of behavioral control before basic motor processes are affected.
authors.affiliation: Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada. ceasdon@rotman-baycrest.on.ca
authors.forename: C M
authors.initials: CM
authors.lastname: Easdon
authors.forename: M
authors.initials: M
authors.lastname: Vogel-Sprott
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000523:psychology*; D001519:Behavior / Q000187:drug effects*; D002492:Central Nervous System Depressants / Q000494:pharmacology*; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008606:Mental Processes; D011597:Psychomotor Performance; D011930:Reaction Time / Q000502:physiology; D011795:Surveys and Questionnaires
chemical_list: D002492:Central Nervous System Depressants; D000431:Ethanol