Melatonin but not vitamins C and E maintains glutathione homeostasis in t-butyl hydroperoxide-induced mitochondrial oxidative stress.
Martín
M
M
Departamento de Fisiología, Instituto de Biotecnología, Universidad de Granada, E-18012 Granada, Spain. dacuna@goliat.ugr.es
Macías
M
M
Escames
G
G
León
J
J
Acuña-Castroviejo
D
D
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001205:Ascorbic Acid / Q000494:pharmacology; D002839:Chromans / Q000494:pharmacology; D005978:Glutathione / Q000378:metabolism*; D019803:Glutathione Disulfide / Q000378:metabolism; D006706:Homeostasis / Q000187:drug effects* / Q000502:physiology; D008550:Melatonin / Q000494:pharmacology; D008928:Mitochondria / Q000187:drug effects* / Q000502:physiology; D010084:Oxidation-Reduction / Q000187:drug effects; D018384:Oxidative Stress / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D014810:Vitamin E / Q000494:pharmacology; D020122:tert-Butylhydroperoxide / Q000494:pharmacology
D000975:Antioxidants; D002839:Chromans; D014810:Vitamin E; D020122:tert-Butylhydroperoxide; D005978:Glutathione; D008550:Melatonin; D001205:Ascorbic Acid; C010643:6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid; D019803:Glutathione Disulfide