Dorsal rhizotomy changes the spontaneous neuronal activity of nuclei in the medial thalamus.
The aim of this study was to examine the influence of unilateral dorsal root section at the cervicothoracic level of the spinal cord on the spontaneous neuronal activity of medial thalamic nuclei in the rat. Single unit extracellular recordings from thalamic nuclei, nc. parafascicularis and nc. centralis lateralis, were obtained with glass micropipettes. The abnormal bursting activity of these nuclei following deafferentation was registered, although a correlation between the occurrence of this activity and the degree of autotomy behavior was not found. Such bursts were never observed in the studied thalamic nuclei of control rats.
Vaculín
S
S
Department of Normal, Pathological and Clinical Physiology, Charles University, Third Faculty of Medicine, Prague, Czech Republic. svaculin@lf3.cuni.cz
Franek
M
M
Rokyta
R
R
D000818:Animals; D001522:Behavior, Animal; D004594:Electrophysiology; D008297:Male; D020645:Mediodorsal Thalamic Nucleus / Q000166:cytology / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D011184:Postoperative Period; D051381:Rats; D017208:Rats, Wistar; D019051:Rhizotomy; D012652:Self Mutilation / Q000523:psychology