title: Medullary monoamine levels during experimental tooth movement.
abstract: We investigated possible influence of nociception induced by experimental tooth movement on the medullary monoaminergic inhibitory systems. Forty-eight hours after the start of the experimental tooth movement, significant increases in dorsal serotonin (5-HT), dopamine (DA), norepinephrine (NE), 5-hydroxyindoleacetic acid (5-HIAA), and dihydroxyphenylacetic acid (DOPAC) levels were detected with ipsilateral dominance. These results suggest that the nociception induced by experimental tooth movement might be under modulation of serotonergic, noradrenergic, and dopaminergic systems.
authors.affiliation: Department of Orthodontics, Okayama University Dental School, 2-5-1, Shikata-cho, Okayama 700-8525, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yamashiro
authors.forename: H
authors.initials: H
authors.lastname: Kabuto
authors.forename: T
authors.initials: T
authors.lastname: Fukunaga
authors.forename: N
authors.initials: N
authors.lastname: Ogawa
authors.forename: T
authors.initials: T
authors.lastname: Takano-Yamamoto
mesh_terms: D015102:3,4-Dihydroxyphenylacetic Acid / Q000378:metabolism; D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism*; D002395:Catecholamines / Q000378:metabolism; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D008297:Male; D008526:Medulla Oblongata / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012016:Reference Values; D012701:Serotonin / Q000378:metabolism; D014087:Tooth Movement Techniques
chemical_list: D015306:Biogenic Monoamines; D002395:Catecholamines; D015102:3,4-Dihydroxyphenylacetic Acid; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid