title: Synthetic studies of zoanthamine/norzoanthamine: biogenetic-like one-step construction of the heterocyclic aminal core (CDEFG ring) from a monocyclic precursor.
abstract: Biogenetic-like one-step construction of the pentacyclic aminal core of zoanthamine/norzoanthamine alkaloids was accomplished in high yield from the suitably protected monocyclic aminohydroxy diketocarboxylic acid 7 by heating in aqueous acetic acid.
authors.affiliation: Faculty of Pharmaceutical Sciences, Science University of Tokyo, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Hikage
authors.forename: H
authors.initials: H
authors.lastname: Furukawa
authors.forename: K
authors.initials: K
authors.lastname: Takao
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
mesh_terms: D000470:Alkaloids; D001381:Azepines / Q000138:chemical synthesis*; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D006576:Heterocyclic Compounds, 4 or More Rings; D009682:Magnetic Resonance Spectroscopy; D011804:Quinolines / Q000138:chemical synthesis*; D013055:Spectrophotometry, Infrared
chemical_list: D000470:Alkaloids; D001381:Azepines; D006571:Heterocyclic Compounds; D006576:Heterocyclic Compounds, 4 or More Rings; D011804:Quinolines; C400280:norzoanthamine