Role of autologous blood transfusion in sacral tumor resection: patient selection and recovery after surgery and blood donation.
We carried out sacral en-bloc resection in six patients (three with chordoma; one with pheochromocytoma; one with malignant schwannoma; and one with giant cell tumor) using preoperatively collected autologous blood, to avoid homologous blood transfusion. An average of 3200 ml was collected preoperatively, with patients receiving recombinant human erythropoietin (r-HuEPO), at a total dose of 130 000 units on average. In four patients, we were able to accomplish the surgery without homologous blood transfusion. Postoperatively, the hemoglobin level in these four patients recovered to the pre-collective level in 4.5 weeks, on average. These clinical results indicate that en-bloc sacrectomy, which requires a large volume of blood transfusion, can be accomplished with preoperatively collected autologous blood alone.
Nakai
S
S
Department of Orthopedic Surgery, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan.
Yoshizawa
H
H
Kobayashi
S
S
Naga
K
K
Ichinose
H
H
D000310:Adrenal Gland Neoplasms / Q000097:blood / Q000601:surgery; D000368:Aged; D001782:Blood Donors; D016063:Blood Loss, Surgical / Q000517:prevention & control; D001804:Blood Transfusion, Autologous; D002817:Chordoma / Q000097:blood / Q000601:surgery; D004921:Erythropoietin / Q000008:administration & dosage; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000097:blood / Q000601:surgery; D006452:Hemoglobinometry; D006801:Humans; D007023:Hypotension, Controlled; D008297:Male; D008875:Middle Aged; D009442:Neurilemmoma / Q000097:blood / Q000601:surgery; D010673:Pheochromocytoma / Q000097:blood / Q000556:secondary / Q000601:surgery; D011994:Recombinant Proteins; D012447:Sacrum / Q000601:surgery*; D013125:Spinal Neoplasms / Q000097:blood / Q000556:secondary / Q000601:surgery*
D011994:Recombinant Proteins; D004921:Erythropoietin