Effect of peroxidase on the development of experimental leprosy in mice after intraplantar infection.
Lyophilized horseradish peroxidase (activity 100 U/mg) administered per os in a dose of 100-200 mg/kg fodder enhanced bactericidal activity of phagocytes in mice experimentally infected with Mycobacterium leprae, which manifested in suppression of M. leprae growth in comparison with untreated controls.
Maslov
A K
AK
Institute of Leprosy, Ministry of Health of Russian Federation, Astrakhan.
Kalyanina
O V
OV
D000818:Animals; D007109:Immunity / Q000187:drug effects; D007918:Leprosy / Q000188:drug therapy* / Q000276:immunology*; D051379:Mice; D008808:Mice, Inbred CBA; D009166:Mycobacterium leprae; D009195:Peroxidase / Q000008:administration & dosage* / Q000627:therapeutic use
D009195:Peroxidase