title: Current international trends in severe acute brain trauma.
abstract: A comprehensive review is presented on current international trends regarding research and management of severe acute brain trauma. Controversial issues are thoroughly discussed and an attempt is made to clarify questionable aspects from pertinent publications in the international literature. A proposition is made to manage not only intracranial pressure and perfusion pressure, but also cerebral hemometabolic parameters in these critically ill patients. Currently available management guidelines are not evidence-based.
authors.affiliation: Comprehensive International Center for Neuroemergencies, Federal University of Sao Paulo, Brazil.
authors.forename: J
authors.initials: J
authors.lastname: Cruz
mesh_terms: D000208:Acute Disease; D001921:Brain / Q000098:blood supply; D001930:Brain Injuries / Q000628:therapy*; D003422:Critical Care / Q000639:trends*; D006801:Humans; D007427:Intracranial Pressure; D010101:Oxygen Consumption; D012720:Severity of Illness Index