Hemolytic-uremic syndrome as a presenting form of acute lymphocytic leukemia.
We report an 8-year-old girl who presented with hemolytic-uremic syndrome (HUS) as the onset manifestation of acute lymphocytic leukemia (ALL). The patient was admitted to the hospital for renal failure, thrombocytopenia, and anemia during a HUS outbreak. She was discharged 2 weeks later with normal renal function. One month later the girl presented with clinical and laboratory signs consistent with a diagnosis of ALL. The short time interval between HUS and ALL suggests that HUS was probably an early manifestation of acute leukemia.
Martini
G
G
Department of Pediatrics, University of Padova, Italy.
Dall'Amico
R
R
Murer
L
L
Montini
G
G
D'Avino
A
A
Zacchello
G
G
D002648:Child; D003937:Diagnosis, Differential; D004196:Disease Outbreaks; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis*