Visceral obesity and the risk of ischaemic heart disease: insights from the Québec Cardiovascular Study.
There is no doubt that visceral obesity increases the susceptibility to IHD, emphasizing the need to consider this condition in the risk management of IHD. The use of CT or MRI as clinical tools to assess visceral adipose tissue accumulation does not appear to be justified, however, mostly because of the costs of the procedures and the limited availability of the necessary apparatus. The waist:hip ratio has been used extensively as an indicator of body fat distribution. However, it has been shown that the waist:hip ratio is less accurate than the waist circumference alone or the sagittal diameter in predicting visceral adipose tissue accumulation, particularly when monitoring changes in visceral adipose tissue mass over time.79 Also, the prediction of visceral adipose tissue levels by the waist circumference alone, as opposed to the waist:hip ratio, does not appear to be affected by gender or by the degree of obesity.80 For these reasons we have proposed that the waist circumference should be systematically measured in managing the risk of IHD. It is a simple and inexpensive measurement to perform, while providing potentially critical information on the risk profile of both men and women.80 We believe that identification of viscerally obese patients, a high-risk population for IHD, should be considered as a critical step in the risk management of IHD.
Lamarche
B
B
Lipid Research Center, CHUL Research Center, Québec, Canada.
Lemieux
S
S
Dagenais
G R
GR
Després
J P
JP
D008078:Cholesterol, LDL / Q000097:blood; D006801:Humans; D006946:Hyperinsulinism / Q000150:complications / Q000378:metabolism; D007333:Insulin Resistance; D008297:Male; D017202:Myocardial Ischemia / Q000150:complications* / Q000378:metabolism*; D009765:Obesity / Q000150:complications* / Q000378:metabolism*; D011446:Prospective Studies; D011792:Quebec; D012307:Risk Factors
D008078:Cholesterol, LDL