title: The effects of dietary biotin supplementation on vertical fissures of the claw wall in beef cattle.
abstract: A clinical field trial was performed on a herd of Hereford beef cows in central Saskatchewan. The herd had a history of being severely affected with vertical fissures. The objective of the study was to determine the effects of supplemental dietary biotin on the prevalence of vertical fissures in beef cows. In June 1994 and June 1995, 1- and 2-year-old heifers were randomly allocated into 2 treatment groups, each composed of 79 animals. One group received a 10 mg/head/day biotin-supplemented free-choice mineral supplement, while the other groups received an identical free-choice mineral without the biotin supplementation. The claws from these animals were evaluated in June 1994, October 1994, June 1995, October 1995, and June 1996 for the presence of vertical fissures. Supplemental dietary biotin significantly increased serum levels of biotin and significantly increased claw hardness in supplemented cows. Both groups of heifers started the trial without vertical fissures. After 18 months, 15% of the cows fed supplemental dietary biotin had vertical fissures compared with 33% in the nonsupplemented group. The difference was statistically significant (P = 0.01).
authors.affiliation: Department of Herd Medicine and Theriogenology, University of Saskatchewan, Saskatoon, Saskatchewan.
authors.forename: J R
authors.initials: JR
authors.lastname: Campbell
authors.forename: P R
authors.initials: PR
authors.lastname: Greenough
authors.forename: L
authors.initials: L
authors.lastname: Petrie
mesh_terms: D000818:Animals; D001710:Biotin / Q000008:administration & dosage / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control*; D019587:Dietary Supplements; D005534:Foot Diseases / Q000517:prevention & control / Q000662:veterinary*; D006724:Hoof and Claw / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D001710:Biotin