Acute porphyric disorders.
Acute porphyrias are classified into 3 distinct groups of rare genetic disorders of metabolic enzyme biosynthesis. Acute porphyrias can significantly impact multiple organ systems, which often provides a challenge to the dentist presented with such a patient. A case of hereditary coproporphyria is reported in a patient with many of the classical signs and symptoms. The patient also had complex dental needs that required special medical and pharmacotherapeutic modifications. The acute porphyrias are reviewed by the authors with presentation of this challenging case. Recommendations for other dental health care professionals encountering these patients are then presented.
Moore
A W
AW
University of Florida College of Dentistry, Parker E. Mahan, Facial Pain Center, Gainesville 32610-0414, USA.
Coke
J M
JM
D000208:Acute Disease; D000328:Adult; D017742:Dental Care for Chronically Ill; D003731:Dental Caries / Q000209:etiology; D005260:Female; D006801:Humans; D009059:Mouth Diseases / Q000209:etiology*; D010518:Periodontitis / Q000209:etiology; D011164:Porphyrias / Q000145:classification / Q000150:complications / Q000378:metabolism / Q000628:therapy; D017094:Porphyrias, Hepatic / Q000150:complications*; D013705:Temporomandibular Joint Disorders / Q000209:etiology