Synapse formation: if it looks like a duck and quacks like a duck ....
Neuroligin and neurexin form an intercellular adhesion complex sufficient to trigger formation of functional presynaptic elements in vitro. This single molecular interaction appears to initiate clustering of synaptic vesicles, assembly of vesicle-release machinery and morphological changes at the presynaptic membrane.
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Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
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D000818:Animals; D006801:Humans; D009419:Nerve Tissue Proteins / Q000378:metabolism / Q000502:physiology; D011485:Protein Binding; D013569:Synapses / Q000502:physiology*
D009419:Nerve Tissue Proteins