Ethyl 5-methyl-4-(2,5,5-trimethyl-1, 3-dioxan-2-yl)isoxazole-3-carboxylate.
The title compound, C(14)H(21)NO(5), possesses an isoxazolyl group in the axial position of the 1,3-dioxanyl ring. The two rings are rotated about the bond joining them such that the two C(methyl)-C(dioxanyl)-C-C torsion angles are 92.1 (2) and -84.1 (2) degrees. In this conformation, neither the methyl nor ethoxycarbonyl substituents on the isoxazole are presented towards the dioxanyl chair.
Zhou
P
P
Department of Chemistry, University of Idaho, Moscow, ID 83844, USA.
Fisher
J D
JD
Staples
R J
RJ
Vij
A
A
Natale
N R
NR
D018360:Crystallography, X-Ray; D004146:Dioxanes / Q000138:chemical synthesis / Q000737:chemistry*; D007555:Isoxazoles / Q000138:chemical synthesis / Q000737:chemistry*; D008024:Ligands; D008958:Models, Molecular; D008968:Molecular Conformation; D018091:Receptors, AMPA
D004146:Dioxanes; D007555:Isoxazoles; D008024:Ligands; D018091:Receptors, AMPA; C414939:ethyl 5-methyl-4-(2,5,5-trimethyl-1,3-dioxan-2-yl)isoxazole-3-carboxylate