Laboratory detection of extended-spectrum beta-lactamases (ESBLs)--the need for a reliable, reproducible method.
A reason for the under-recognition of extended-spectrum beta-lactamase (ESBL)-mediated resistance has been the lack of a convenient and sensitive method for recognising ESBL-producing strains. This paper reviews the relative merits and demerits of various methods used.
Essack
S Y
SY
Department of Pharmacy, University of Durban-Westville, Private Bag X54001, 4000, Durban, South Africa. sessack@pixie.udw.ac.za
D007709:Klebsiella / Q000187:drug effects / Q000201:enzymology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000032:analysis* / Q000096:biosynthesis
D001618:beta-Lactamases