Genetics of childhood disorders: XVIII. ADHD, Part. 2: Norepinephrine has a critical modulatory influence on prefrontal cortical function.
Arnsten
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Section of Neurobiology, Yale University School of Medicine, New Haven, CT 06520, USA. Paul.Lombroso@Yale.edu
D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000818:Animals; D001289:Attention Deficit Disorder with Hyperactivity / Q000235:genetics* / Q000378:metabolism*; D002560:Cerebrovascular Circulation / Q000502:physiology; D002648:Child; D003071:Cognition / Q000502:physiology; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D009638:Norepinephrine / Q000096:biosynthesis / Q000378:metabolism / Q000502:physiology*; D017397:Prefrontal Cortex / Q000098:blood supply / Q000378:metabolism / Q000502:physiology*; D018340:Receptors, Adrenergic, alpha-1 / Q000378:metabolism; D018341:Receptors, Adrenergic, alpha-2 / Q000378:metabolism*
D000316:Adrenergic alpha-Agonists; D018340:Receptors, Adrenergic, alpha-1; D018341:Receptors, Adrenergic, alpha-2; D009638:Norepinephrine