title: Effects of Lactobacillus amylovorus and Bifidobacterium breve on cholesterol.
abstract: To determine the validity of the hypothesis of assimilation and/or precipitation of cholesterol by Lactobacillus and Bifidobacterium species, culture were undertaken in TPY medium containing oxgall or taurocholic acid. In the case of growing cells, both strains were able to remove cholesterol in the presence of bile salts. Nevertheless, the behaviour was different according to the kind of bile salt. In the presence of taurocholic acid, the removal of cholesterol was due to both bacterial uptake and precipitation. In the presence of Oxgall, bacterial uptake and precipitation were observed for Lactobacillus but only precipitation occurred for Bifidobacterium.
authors.affiliation: Université Henri Poincaré-Nancy 1, Laboratoire de Biochimie des Bactéries Gram +, Vandoeuvre les Nancy and CIRDC Danone, Le Plessis Robinson, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Grill
authors.forename: C
authors.initials: C
authors.lastname: Cayuela
authors.forename: J M
authors.initials: JM
authors.lastname: Antoine
authors.forename: F
authors.initials: F
authors.lastname: Schneider
mesh_terms: D001644:Bifidobacterium / Q000254:growth & development / Q000378:metabolism*; D001647:Bile Acids and Salts / Q000494:pharmacology; D011232:Chemical Precipitation; D002784:Cholesterol / Q000737:chemistry* / Q000378:metabolism*; D003470:Culture Media; D007778:Lactobacillus / Q000254:growth & development / Q000378:metabolism*; D013656:Taurocholic Acid / Q000494:pharmacology
chemical_list: D001647:Bile Acids and Salts; D003470:Culture Media; D013656:Taurocholic Acid; D002784:Cholesterol