title: Prognosis of ischemic colitis: comparison of color doppler sonography with early clinical and laboratory findings.
abstract: OBJECTIVE
  The objective of this study was to compare the value of color Doppler sonography with early clinical and laboratory findings in determining the prognosis of patients with ischemic colitis.
  
  
  METHODS
  We reviewed the early clinical, laboratory, and color Doppler sonographic data of 24 patients with ischemic colitis. The patients were divided into two groups on the basis of their outcome. The first group comprised the patients with transient ischemia who recovered uneventfully, and the second group included the patients who needed surgery because of symptomatic transmural colic gangrene or colic stricture. Clinical data and laboratory values were compared with color Doppler sonographic findings including colic wall thickness, presence of stratification, and arterial flow in the bowel wall.
  
  
  RESULTS
  At univariate analysis, increased age (p = 0.007), leukocyte count (p = 0.030), lactate dehydrogenase level (p = 0.030), blood lactate level (p = 0.041), and absence of vascular flow in the colic wall (p<0.001) were significantly related to complicated ischemic colitis. At multivariate analysis, absence of arterial flow was the only significant predictor of complicated ischemic colitis (p = 0.002), with a sensitivity of 82%, a specificity of 92%, a positive predictive value of 90%, and a negative predictive value of 86%.
  
  
  CONCLUSIONS
  Absence of arterial flow in the wall of the ischemic colon on initial color Doppler sonography is suggestive of an unfavorable outcome and is more closely associated with outcome than early clinical and laboratory findings.
authors.affiliation: Department of Radiology, Université Catholique de Louvain, St-Luc University Hospital, Avenue Hippocrate 10, B-1200 Brussels, Belgium.
authors.forename: E M
authors.initials: EM
authors.lastname: Danse
authors.forename: B E
authors.initials: BE
authors.lastname: Van Beers
authors.forename: J
authors.initials: J
authors.lastname: Jamart
authors.forename: P
authors.initials: P
authors.lastname: Hoang
authors.forename: P F
authors.initials: PF
authors.lastname: Laterre
authors.forename: F C
authors.initials: FC
authors.lastname: Thys
authors.forename: A
authors.initials: A
authors.lastname: Kartheuser
authors.forename: J
authors.initials: J
authors.lastname: Pringot
mesh_terms: D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D017091:Colitis, Ischemic / Q000000981:diagnostic imaging* / Q000201:enzymology; D003106:Colon / Q000098:blood supply; D005260:Female; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D019344:Lactic Acid / Q000097:blood*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D018615:Ultrasonography, Doppler, Color
chemical_list: D019344:Lactic Acid; D007770:L-Lactate Dehydrogenase