title: Optimum imaging for sinonasal malignancy.
abstract: A combination of computed tomography (CT) and magnetic resonance imaging (MRI) is now established as the optimum assessment of sinonasal malignancy. CT and MRI are of particular value in assessing the skull base, orbit and pteryo-palatine and infratemporal fossae. Although MRI offers better differentiation of tumour from surrounding tissue and fluid, coronal CT is still required for the demonstration of bone erosion particularly in the region of the cribriform plate. Thus the extent of local tumour spread may be determined with a degree of accuracy in excess of 98 per cent. However, the final determinant of penetration of the dura and orbital periosteum requires per-operative frozen section assessment. A knowledge of the tissue characteristics and site of origin can be of value in distinguishing some of the commoner sinonasal malignancies such as squamous cell carcinoma, adenocarcinoma, adenoid cystic carcinoma, olfactory neuroblastoma and chondrosarcoma. Imaging, particularly MRI also plays an important role in the post-therapeutic follow-up of patients, indicating areas of residual or recurrent disease, defining suspicious areas for biopsy. Post-operative surveillance is best achieved with three planar T1-weighted MRI, with, and without, gadolinium and axial T2-weighted sequences. The subtraction of the T1 pre- and post gadolinium T1 sequences can be of particular value in delineating recurrence.
authors.affiliation: Institute of Laryngology and Otology, University College London, UK.
authors.forename: G
authors.initials: G
authors.lastname: Lloyd
authors.forename: V J
authors.initials: VJ
authors.lastname: Lund
authors.forename: D
authors.initials: D
authors.lastname: Howard
authors.forename: L
authors.initials: L
authors.lastname: Savy
mesh_terms: D002813:Chondrosarcoma / Q000175:diagnosis; D018304:Esthesioneuroblastoma, Olfactory / Q000175:diagnosis; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis* / Q000628:therapy; D012888:Skull Neoplasms / Q000175:diagnosis; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019786:Gadolinium DTPA