title: [Efficacy of patient-controlled epidural analgesia using a disposable PCA device].
abstract: We evaluated efficacy of patient-controlled epidural analgesia (PCEA) using a disposable PCA device (3.0 ml type). Twenty-two patients for elective gynecological surgery were randomized into two groups. Patients of the continuous epidural group received epidural fentanyl (15 micrograms.ml-1) with bupivacaine (1.25 mg.ml-1) from a disposable infusion pump (infusion rate: 2.1 ml.hr-1). Patients of the PCEA group received the same anesthetic solution from the same infusion pump serially connected to the disposable PCA device. There were no significant differences in postoperative visual analogue scale (VAS) scores at rest and with movement between the two groups. However, VAS scores significantly decreased from 6.8 +/- 1.6 to 1.0 +/- 1.3 when the PCA device was used for severe pain. This suggests that segmental analgesic effect might be obtained by diffusion of anesthetic solution in the epidural space after 3.0 ml PCEA bolus administration. The incidences of side effects were similar in both groups. Respiratory depression and sedative effects were not observed in both groups. We conclude that PCEA using a disposable PCA device (3.0 ml type) seems to be effective for postoperative pain relief.
authors.affiliation: Department of Anesthesia, Sapporo National Hospital.
authors.forename: J
authors.initials: J
authors.lastname: Kakehata
authors.forename: M
authors.initials: M
authors.lastname: Shibuya
authors.forename: S
authors.initials: S
authors.lastname: Yokota
authors.forename: C
authors.initials: C
authors.lastname: Takigawa
authors.forename: H
authors.initials: H
authors.lastname: Tsujinaga
authors.forename: S
authors.initials: S
authors.lastname: Tsutahara
authors.forename: Y
authors.initials: Y
authors.lastname: Morimoto
authors.forename: O
authors.initials: O
authors.lastname: Kemmotsu
mesh_terms: D000328:Adult; D000368:Aged; D015360:Analgesia, Epidural / Q000295:instrumentation*; D016058:Analgesia, Patient-Controlled / Q000295:instrumentation*; D000701:Analgesics, Opioid / Q000008:administration & dosage; D000779:Anesthetics, Local / Q000008:administration & dosage; D002045:Bupivacaine / Q000008:administration & dosage; D004209:Disposable Equipment; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage; D013509:Gynecologic Surgical Procedures; D006801:Humans; D007260:Infusion Pumps; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy*
chemical_list: D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D005283:Fentanyl; D002045:Bupivacaine