Light and confocal laser-scanning microscopical evidences for complementary patterns of glial fibrillary acidic protein and Wisteria floribunda agglutinin labeled structures in human and rat brain.
We investigated the pattern of glial fibrillary acidic protein (GFAP) and Wisteria floribunda agglutinin (WFA) labeled structures in the superior colliculus and in the somatosensory cortex of humans and rats of different age groups using immunohistochemical methods, light and confocal laser-scanning microscopy. We never found a double labeling of WFA and GFAP positive structures neither in the superior colliculus nor in the cortex of both man and rat. The complementary pattern of WFA and GFAP labeling was present both at the macroscopic and microscopic level. We found a clear prevalence of either WFA or GFAP expression in the arborization of the astrocytes as well as in the pattern of lamination.
Hilbig
H
H
Institute of Anatomy, University of Leipzig, Germany.
Bidmon
H J
HJ
Dinse
H
H
Müller
A
A
Zilles
K
K
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001253:Astrocytes / Q000737:chemistry; D001344:Autopsy; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis / Q000737:chemistry*; D006801:Humans; D007150:Immunohistochemistry; D037102:Lectins / Q000032:analysis / Q000737:chemistry*; D008297:Male; D018613:Microscopy, Confocal; D008859:Microscopy, Polarization; D008875:Middle Aged; D051381:Rats; D013003:Somatosensory Cortex / Q000737:chemistry*; D013477:Superior Colliculi / Q000737:chemistry*
D005904:Glial Fibrillary Acidic Protein; D037102:Lectins