The cell cycle genes cycA1;1 and cdc2Os-3 are coordinately regulated by gibberellin in planta.
Internodal growth of deepwater rice (Oryza sativa L.) can achieve rates of up to 10 mm h(-1). In submergence-induced plants, gibberellic acid activates the cell division cycle first at the G1 --> S phase transition with a subsequent increase in mitotic activity. The proteins cycA1;1 and cdc2Os-3 are the regulatory and catalytic subunits, respectively, of cyclin-dependent protein kinases (CDKs) which are central to cell cycle regulation. Both genes are regulated by gibberellic acid in a coordinate manner with transcripts accumulating in the G2 phase prior to the B2-type mitotic cyclins described previously (M. Sauter et al. 1995, Plant J 7: 623-632), suggesting a distinct role in regulating G2/M phase progression. Since cdc2Os-3 belongs to a group of CDKs that have no counterparts in animals, it may function in a plant-specific gibberellin-regulated cell division process.
Fabian
T
T
Institut für Allgemeine Botanik, AMPII, Universität Hamburg, Germany.
Lorbiecke
R
R
Umeda
M
M
Sauter
M
M
D002453:Cell Cycle / Q000235:genetics*; D002478:Cells, Cultured; D003001:Cloning, Molecular; D018844:Cyclin-Dependent Kinases / Q000235:genetics*; D016195:G2 Phase; D018506:Gene Expression Regulation, Plant / Q000187:drug effects / Q000502:physiology*; D017343:Genes, Plant; D005875:Gibberellins / Q000494:pharmacology*; D008938:Mitosis; D012275:Oryza / Q000166:cytology* / Q000201:enzymology / Q000235:genetics*; D021122:Protein Subunits; D011994:Recombinant Proteins / Q000096:biosynthesis
D005875:Gibberellins; D021122:Protein Subunits; D011994:Recombinant Proteins; D018844:Cyclin-Dependent Kinases