[Effect of reducing agents-antioxidants on rat uterine aromatase activity in vitro].
The effect of different reductors-antioxidants (ascorbic acid, cysteine, glutathione-SH and hydroquinone) on purified rat uterine aromatase activity was studied. It was established that all these compounds were aromatase activators. The possible mechanisms of this activation were discussed.
Iasinskaia
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I. I. Mechnikov Odessa State University. inna@farlep.net
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001141:Aromatase / Q000378:metabolism*; D001205:Ascorbic Acid / Q000494:pharmacology; D003545:Cysteine / Q000494:pharmacology; D020536:Enzyme Activators / Q000494:pharmacology; D005260:Female; D005978:Glutathione / Q000494:pharmacology; D006873:Hydroquinones / Q000494:pharmacology; D051381:Rats; D019163:Reducing Agents / Q000494:pharmacology*; D014599:Uterus / Q000187:drug effects* / Q000201:enzymology
D000975:Antioxidants; D020536:Enzyme Activators; D006873:Hydroquinones; D019163:Reducing Agents; D001141:Aromatase; D005978:Glutathione; D003545:Cysteine; D001205:Ascorbic Acid; C031927:hydroquinone