Zinc-responsive dermatosis in a red wolf (canis rufus).
An 18-mo-old male red wolf (Canis rufus) presented with footpad hyperkeratosis, suppurative paronychia, distal limb pyoderma, and peripheral lymphadenopathy. Diet for the previous 11 mo consisted of a mixture of two commercially prepared dog foods with a mineral supplement containing primarily calcium. Culture of the draining tracts on the distal limbs yielded a mixed population of opportunistic bacteria. Histopathologic findings were consistent with a diagnosis of zinc deficiency. Medical therapy consisted of 15 mg/kg amoxicillin p.o. b.i.d. and 10 mg/kg zinc sulfate p.o. s.i.d. Calcium supplementation was discontinued. Clinical signs resolved by 10 wk after the initiation of treatment.
Kearns
K
K
Department of Comparative Medicine, College of Veterinary Medicine, The University of Tennessee, Knoxville 37901-1071, USA.
Sleeman
J
J
Frank
L
L
Munson
L
L
D000658:Amoxicillin / Q000627:therapeutic use; D000818:Animals; D002136:Calcium, Dietary / Q000009:adverse effects*; D017809:Fatal Outcome; D006651:Histocytochemistry; D008297:Male; D010406:Penicillins / Q000627:therapeutic use; D011711:Pyoderma / Q000628:therapy / Q000662:veterinary; D012008:Recurrence; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D019596:Wolves; D015032:Zinc / Q000097:blood; D019287:Zinc Sulfate / Q000627:therapeutic use*
D002136:Calcium, Dietary; D010406:Penicillins; D019287:Zinc Sulfate; D000658:Amoxicillin; D015032:Zinc