title: [Melanin complex of the fungus Inonotus obliquus].
abstract: The fungus Inonotus obliquus (Pers.) Pil. synthesised high-molecular-weight phenolic pigments that were assigned to melanins according to their physicochemical properties. It was showed that copper ions (0.008%), pyrocatechol (1.0 mM), and tyrosine (20.0 mM) stimulated the melanogenesis. The production of melanin correlated with the synthesis of o- and p-diphenoloxidases. The fungal melanin had strong antioxidant and genoprotective effects.
authors.affiliation: Institute of Microbiology, National Academy of Sciences of Belarus, Minsk, Belarus.
authors.forename: V G
authors.initials: VG
authors.lastname: Babitskaia
authors.forename: V V
authors.initials: VV
authors.lastname: Shcherba
authors.forename: N V
authors.initials: NV
authors.lastname: Ikonnikova
mesh_terms: D016587:Antimutagenic Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D001487:Basidiomycota / Q000187:drug effects / Q000378:metabolism*; D002396:Catechols / Q000494:pharmacology; D003300:Copper / Q000494:pharmacology; D008543:Melanins / Q000096:biosynthesis / Q000378:metabolism* / Q000494:pharmacology; D014443:Tyrosine / Q000494:pharmacology
chemical_list: D016587:Antimutagenic Agents; D000975:Antioxidants; D002396:Catechols; D008543:Melanins; D014443:Tyrosine; D003300:Copper; C034221:catechol