title: [Invasive disease caused by Streptococcus pyogenes. Report of a case with cutaneous and kidney metastasis].
abstract: Few cases of invasive disease due to Streptococcus pyogenes in children have been described. Greater knowledge of this disease is needed due to its increasing incidence and seriousness. New serotypes have been discovered with greater virulence due to exotoxin production and to the development of resistance to phagocytosis. We present a case of invasive disease due to S. pyogenes with bacteremia and cutaneous and kidney metastasis, in a non-immunodeficient child. The case is of interest because kidney dissemination has not been described in the literature and because evolution was satisfactory with endovenous beta-lactamica treatment during 15 days for only 48 hours. The importance of ruling out multi-organ metastatic foci, including use of urine cultures to rule out kidney involvement are highlighted. The epidemiological, pathogenic, clinical and diagnostic aspects of this entity, as reported in recent literature, are described.
authors.affiliation: Servicio Dermatología. Unitat Integrada Hospital Clínic-Hospital Sant Joan de Déu. Universitat de Barcelona.
authors.forename: I
authors.initials: I
authors.lastname: Jordán
authors.forename: M T
authors.initials: MT
authors.lastname: García
authors.forename: J
authors.initials: J
authors.lastname: García
authors.forename: A
authors.initials: A
authors.lastname: Vicente
authors.forename: C
authors.initials: C
authors.lastname: Luaces
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D007674:Kidney Diseases / Q000382:microbiology*; D012871:Skin Diseases / Q000382:microbiology*; D013290:Streptococcal Infections / Q000150:complications*; D013297:Streptococcus pyogenes