title: Experimental study of the effect of external counterpulsation on blood circulation in the lower extremities.
abstract: A bidirectional ultrasonic Doppler flowmeter with direct single sideband separation was used to measure blood flow in the femoral and dorsalis pedis arteries of 18 normal volunteers. Changes in blood-flow velocity and volume during external counterpulsation (ECP) with various sustaining times (the time for maintaining pressure) for inflation were studied. The results showed that blood-flow velocity in the femoral and dorsalis pedis arteries is increased significantly by ECP, but the change is not closely related to the duration of inflation. For a short sustaining time, the net forward blood-flow volume in arteries increased remarkably, but at longer sustaining times it dropped back significantly to a value even lower than that before ECP. The sustaining time for inflation to produce the maximum net forward flow volume (the optimal sustaining time of inflation) was found to be at one-quarter to one-third of the cardiac cycle. In a second study, changes in the calibre of the femoral artery and its collateral and anastomotic branches in the hind extremities in 5 dogs before and after ECP with an optimal sustaining time of inflation were examined by femoral arteriography. The experiments showed that the patency of collateral and anastomotic branches of the femoral artery was greater before than after ECP. The study suggests that ECP could be an effective treatment for improving the blood circulation in extremities.
authors.affiliation: External Counterpulsation Laboratory, Clinical Medical College, Shanghai Medical University, China. kjcsfph@public9.sta.net.cn
authors.forename: D
authors.initials: D
authors.lastname: Cai
authors.forename: R
authors.initials: R
authors.lastname: Wu
authors.forename: Y
authors.initials: Y
authors.lastname: Shao
mesh_terms: D000328:Adult; D000818:Animals; D001783:Blood Flow Velocity; D001794:Blood Pressure; D001810:Blood Volume; D015908:Counterpulsation; D004285:Dogs; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000502:physiology; D006801:Humans; D017078:Laser-Doppler Flowmetry; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012039:Regional Blood Flow