title: Growth hormone replacement therapy during transition of patients with childhood-onset growth hormone deficiency into adulthood: what are the issues?
authors.affiliation: Department of Endocrinology, Christie Hospital NHS Trust, Manchester, UK.
authors.forename: S M
authors.initials: SM
authors.lastname: Shalet
authors.forename: R G
authors.initials: RG
authors.lastname: Rosenfeld
mesh_terms: D000328:Adult; D001823:Body Composition / Q000187:drug effects; D001827:Body Height / Q000187:drug effects; D001842:Bone and Bones / Q000187:drug effects / Q000378:metabolism; D002648:Child; D004393:Dwarfism, Pituitary / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D006128:Growth / Q000187:drug effects; D006321:Heart / Q000187:drug effects / Q000502:physiology; D020249:Hormone Replacement Therapy; D019382:Human Growth Hormone / Q000008:administration & dosage / Q000172:deficiency* / Q000627:therapeutic use*; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000502:physiology; D011627:Puberty / Q000502:physiology; D011788:Quality of Life
chemical_list: D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I