title: [Clinical and histological indicators predictive of cervical metastases in laryngeal cancer].
abstract: BACKGROUND
  A study was made of possible clinical and pathological indicators associated with cervical lymph node involvement in laryngeal cancer.
  
  
  METHODS
  Between 1994 and 1997, 85 patients with laryngeal cancer underwent surgery in the ENT department of the Complutense University of Madrid (Spain). A statistical analysis was made to identify clinical and pathological indicators of lymph node metastases.
  
  
  RESULTS
  Predictive indicators (PI) of cervical metastatic disease in our study were: 1) tumor location; 2) low degree of differentiation; 3) invasion > 5 mm deep; 4) perineural invasion; and 5) invasion of the pre-epiglottic space.
authors.affiliation: Departamento de Cirugía II-ORL, Hospital Clínico San Carlos, Universidad Complutense de Madrid.
authors.forename: C
authors.initials: C
authors.lastname: Martín Villares
authors.forename: J
authors.initials: J
authors.lastname: Poch Broto
authors.forename: L
authors.initials: L
authors.lastname: Ortega Medina
authors.forename: M C
authors.initials: MC
authors.lastname: Iglesias Moreno
authors.forename: M J
authors.initials: MJ
authors.lastname: González Gimeno
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000556:secondary*; D002454:Cell Differentiation / Q000502:physiology; D002574:Cervical Vertebrae / Q000473:pathology*; D003430:Cross-Sectional Studies; D006801:Humans; D015994:Incidence; D007822:Laryngeal Neoplasms / Q000473:pathology*; D008207:Lymphatic Metastasis; D011237:Predictive Value of Tests; D015995:Prevalence; D011446:Prospective Studies; D013125:Spinal Neoplasms / Q000453:epidemiology / Q000556:secondary*