title: The use of epidural ropivacaine in high doses for the management of pain from invasive carcinoma of the cervix.
abstract: A case is presented of a young woman with advanced cervical cancer invading the rectum and sacral nerves giving rise to an intractable pain state. The management of her symptoms using a domicillary infusion of diamorphine with high doses of ropivacaine is described. It is believed that this is the first presentation of ropivacaine being used in daily doses approaching 2 g, and the associated problems are discussed.
authors.affiliation: Featherstone Department of Anaesthesia and Intensive Care, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK.
authors.forename: G R
authors.initials: GR
authors.lastname: Harrison
mesh_terms: D000328:Adult; D000577:Amides / Q000627:therapeutic use*; D015360:Analgesia, Epidural / Q000379:methods*; D016058:Analgesia, Patient-Controlled / Q000379:methods; D000779:Anesthetics, Local / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010148:Intractable Pain / Q000188:drug therapy* / Q000209:etiology; D010166:Palliative Care / Q000379:methods; D000077212:Ropivacaine; D002583:Uterine Cervical Neoplasms / Q000150:complications*
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine