title: Dexmedetomidine--a novel sedative for postoperative sedation.
abstract: Dexmedetomidine is new sedative being developed for use in postoperative sedation in ICU. It acts at a 2 adrenoceptors to produce sedation, anxiolysis and analgesia. Patients remain easily rousable and do not suffer significant respiratory depression, consequently dexmedetomidine may be continued post extubation.
authors.affiliation: St. George's Hospital, London, UK.
authors.forename: C
authors.initials: C
authors.lastname: Bradley
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000494:pharmacology / Q000627:therapeutic use*; D016292:Procedural Sedation / Q000379:methods* / Q000451:nursing; D020927:Dexmedetomidine / Q000494:pharmacology / Q000627:therapeutic use*; D016903:Drug Monitoring / Q000379:methods / Q000451:nursing; D011307:Drug Prescriptions; D004335:Drug and Narcotic Control; D005060:Europe; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology / Q000627:therapeutic use*; D011182:Postoperative Care / Q000379:methods* / Q000451:nursing
chemical_list: D000316:Adrenergic alpha-Agonists; D006993:Hypnotics and Sedatives; D020927:Dexmedetomidine