[Methodological approaches to the study of the carcinogenic properties of substances].
Since the methods of investigation of carcinogenicity of different agents have changed drastically, relevant manuals need to be revised and supplemented. A new concept of carcinogenic agents evaluation, criteria for their selection and study are discussed. Working out of criteria for establishing priorities of hazardous substance selection is of vital importance.
Pylev
L N
LN
N. N. Blokhin Center for Oncology Research, Russian Academy of Medical Sciences, Moscow.
Vasil'eva
L A
LA
Pliss
G B
GB
D000818:Animals; D000830:Animals, Laboratory; D002273:Carcinogens / Q000008:administration & dosage / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D009374:Neoplasms, Experimental / Q000139:chemically induced; D012107:Research Design; D013997:Time Factors
D002273:Carcinogens