title: Rosai-Dorfman disease of the larynx.
abstract: We present a case of an 81-year-old man with a history of worsening dysphonia of six months duration. A year before a sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) was diagnosed on a submandibular lymph node biopsy. On presentation the patient showed a mass in the left subglottic area with a modest reduction in the airway space. The patient underwent an endoscopic CO2 laser excision of the mass, without post-operative complications. Histopathological examination and electron microscope images confirmed the previous diagnosis of Rosai-Dorfman disease. The clinical and pathological features of this entity are discussed.
authors.affiliation: Department of Otorhinolaryngology, University of Piemonte Orientale, Novara, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Aluffi
authors.forename: A
authors.initials: A
authors.lastname: Prestinari
authors.forename: A
authors.initials: A
authors.lastname: Ramponi
authors.forename: M
authors.initials: M
authors.lastname: Castri
authors.forename: F
authors.initials: F
authors.lastname: Pia
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D015618:Histiocytosis, Sinus / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007828:Laryngoscopy / Q000379:methods; D008297:Male; D008854:Microscopy, Electron; D014057:Tomography, X-Ray Computed