title: Multiple electrophilic substitution of 1,1,2,2,9,9,10,10-octafluoro
abstract: Synthetic methods for introduction of two substituents into the rings of octafluoroparacyclophane are presented. Nitration gives three isomers with nitro substituents on different rings: pseudo-ortho, pseudo-meta, and pseudo-para, in equal amounts. These dinitro compounds are shown to be precursors of a variety of other disubstituted OFP derivatives. Methods of characterization of isomeric disubstituted OFPs are extensively discussed, and the 1H and 19F NMR spectra of these derivatives are analyzed explicitly.
authors.affiliation: Department of Chemistry, University of Florida, Gainesville 32611-7200, USA.
authors.initials: AJ
authors.lastname: Roche
authors.initials: WR
authors.lastname: Dolbier