title: Quality of sexually transmitted disease treatments in the formal and informal sectors of Bangui, Central African Republic.
abstract: BACKGROUND
  Interventions for upgrading sexually transmitted disease (STD) management in sub-Saharan Africa have focused on the public sector, and to a much lower extent on private medical practitioners and pharmacies. However, in most African cities there is a large informal sector that provides care to many patients with STD symptoms.
  
  
  OBJECTIVE
  To compare the quality of treatments offered to patients with major STD syndromes in the public sector, pharmacies, and the informal sector of the same city.
  
  
  METHODS
  Healthcare providers in health centers, pharmacies, private laboratories, and market drug peddlers in Bangui, Central African Republic, were asked to complete a short form for every patient consulting them with genital complaints. The treatments they ordered were evaluated for their potential efficacy against the major etiologic agents of the syndrome for which the patient consulted.
  
  
  RESULTS
  The majority of male patients with STDs preferred to seek care in pharmacies and in the informal sector. The STD treatments offered to patients with urethral discharge or genital ulcers in pharmacies and in the informal sector tended to focus on a single etiologic agent. The quality of STD treatments offered by drug peddlers and private laboratories was poor, apart from adequate coverage of syphilis in patients with genital ulcers and of candidiasis in women with vaginal discharge. For instance, 41% and 34% of patients with urethral discharge managed by drug peddlers and private laboratories did not receive a drug active against either Neisseria gonorrhoeae or Chlamydia trachomatis, whereas this proportion was 22% in pharmacies and 14% in health centers. For patients with genital ulcers, the proportion offered a drug active against Haemophilus ducreyi was 2% if seen by drug peddlers, 0% in laboratories, 10% in pharmacies, and 25% in health centers. For each syndrome and each category of provider, between one fourth and two thirds of patients had already received another ineffective treatment elsewhere.
  
  
  CONCLUSIONS
  National STD and HIV control programs will have to improve STD management in pharmacies and in the informal sector if they are to have any impact on the dynamics of HIV infection in urban centers.
authors.affiliation: Ministère de la Santé Publique et de la Population, Bangui, République Centrafricaine.
authors.forename: P
authors.initials: P
authors.lastname: Somsé
authors.forename: F
authors.initials: F
authors.lastname: Mberyo-Yaah
authors.forename: P
authors.initials: P
authors.lastname: Morency
authors.forename: M J
authors.initials: MJ
authors.lastname: Dubois
authors.forename: G
authors.initials: G
authors.lastname: Grésenguet
authors.forename: J
authors.initials: J
authors.lastname: Pépin
mesh_terms: D000553:Ambulatory Care; D002488:Central African Republic; D004358:Drug Therapy / Q000191:economics; D005260:Female; D006801:Humans; D008297:Male; D010342:Patient Acceptance of Health Care; D010605:Pharmacy Administration / Q000592:standards*; D017149:Private Sector / Q000458:organization & administration* / Q000592:standards; D011635:Public Health Administration / Q000592:standards*; D011787:Quality of Health Care; D012749:Sexually Transmitted Diseases / Q000188:drug therapy* / Q000517:prevention & control; D016896:Treatment Outcome