title: Pleural fluid characteristics of patients with symptomatic pleural effusion after coronary artery bypass graft surgery.
abstract: BACKGROUND
  This study describes the pleural fluid characteristics of patients who develop symptomatic pleural effusions after coronary artery bypass graft surgery (CABG).
  
  
  METHODS
  Post-CABG patients who underwent a therapeutic thoracentesis for a symptomatic pleural effusion were included unless another explanation for the pleural effusion was present.
  
  
  RESULTS
  During the study, 71 patients (mean age, 61 years) were identified; 49 were men and 22 were women. All patients underwent internal mammary artery grafting. Early effusions (<30 days after CABG) occurred in 45 patients (63%) and late effusions (>/=30 days after CABG) developed in 26 (37%). Early effusions were bloody (median red blood cell count, 706 x 10(12)/L [706,000 mm(3)])with a high eosinophil count (median, 0.385), whereas effusions that occurred in the late period were yellow exudates with predominant lymphocytes (median, 0.68) and monocytes (median, 0.20). The mean pleural fluid level of lactate dehydrogenase was more than 3 times the upper limit of the reference range in serum in early effusions, whereas late effusions had significantly lower lactate dehydrogenase levels.
  
  
  CONCLUSIONS
  Characteristics of early and late effusions differ significantly, suggesting a different pathogenesis of the effusions. Patients who develop a symptomatic pleural effusion after CABG should undergo a therapeutic thoracentesis; however, further investigations are warranted only in patients who have pleural fluid characteristics different from those described.
authors.affiliation: Director of Pulmonary Disease, Saint Thomas Hospital, PO Box 380, 4220 Harding Rd, Nashville, TN 37202, USA.
authors.forename: R T
authors.initials: RT
authors.lastname: Sadikot
authors.forename: J T
authors.initials: JT
authors.lastname: Rogers
authors.forename: D S
authors.initials: DS
authors.lastname: Cheng
authors.forename: P
authors.initials: P
authors.lastname: Moyers
authors.forename: M
authors.initials: M
authors.lastname: Rodriguez
authors.forename: R W
authors.initials: RW
authors.lastname: Light
mesh_terms: D000368:Aged; D001772:Blood Cell Count; D005122:Exudates and Transudates / Q000166:cytology / Q000201:enzymology; D005260:Female; D005947:Glucose / Q000032:analysis; D006801:Humans; D007387:Internal Mammary-Coronary Artery Anastomosis / Q000009:adverse effects*; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008297:Male; D008875:Middle Aged; D019152:Paracentesis / Q000009:adverse effects*; D010996:Pleural Effusion / Q000201:enzymology / Q000209:etiology* / Q000473:pathology*; D011506:Proteins / Q000032:analysis; D013909:Thorax; D013997:Time Factors
chemical_list: D011506:Proteins; D007770:L-Lactate Dehydrogenase; D005947:Glucose