Novel dimeric metabolites from Alternaria tagetica.
Two novel polyketides, bis-7-O-8' '.8-O-7' '- and bis-7-O-7' '. 8-O-8' '-zinniol (2 and 3, respectively) were isolated from the organic crude extract of culture filtrates from Alternaria tagetica. Both structures were determined on the basis of their spectroscopic data (IR, MS, (1)H NMR, (13)C NMR, and 2D NMR experiments) and confirmed by chemical synthesis. Zinniol (1) was isolated as a major component, and its (13)C NMR data was correctly assigned after careful analysis of data from its 2D NMR experiments (HMQC and HMBC).
Gamboa-Angulo
M M
MM
Grupo de Química Orgánica, Unidad de Biotecnología, Centro de Investigación Científica de Yucatán A.C., Apdo. Postal 87 Cordemex 97310, Mérida, Yucatán, México.
Alejos-González
F
F
Escalante-Erosa
F
F
García-Sosa
K
K
Delgado-Lamas
G
G
Peña-Rodríguez
L M
LM
D000528:Alternaria / Q000737:chemistry*; D002849:Chromatography, Gas; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D009183:Mycotoxins / Q000737:chemistry / Q000302:isolation & purification*; D018515:Plant Leaves / Q000382:microbiology; D013055:Spectrophotometry, Infrared; D014992:Xylenes / Q000737:chemistry / Q000302:isolation & purification*
D009183:Mycotoxins; D014992:Xylenes; C414483:bis-7-O-7' '. 8-O-8' '-zinniol; C414482:bis-7-O-8' '.8-O-7' '-zinniol; C051798:zinniol