title: Isoflavonoids from Pueraria mirifica and their estrogenic activity.
abstract: Nine isoflavonoids including a new pterocarpene, puemiricarpene, were isolated from the tuberous root of Pueraria mirifica (Leguminosae). The structure of puemiricarpene was determined by spectroscopic means. Estrogenic activity of the isolated isoflavonoids was tested using MCF-7 human breast cancer cells. Moderate activity was observed for kwakhurin, a prenylated isoflavonoid.
authors.forename: S
authors.initials: S
authors.lastname: Chansakaow
authors.forename: T
authors.initials: T
authors.lastname: Ishikawa
authors.forename: K
authors.initials: K
authors.lastname: Sekine
authors.forename: M
authors.initials: M
authors.lastname: Okada
authors.forename: Y
authors.initials: Y
authors.lastname: Higuchi
authors.forename: M
authors.initials: M
authors.lastname: Kudo
authors.forename: C
authors.initials: C
authors.lastname: Chaichantipyuth
mesh_terms: D004968:Estrogens, Non-Steroidal / Q000737:chemistry* / Q000494:pharmacology*; D007887:Fabaceae / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D007529:Isoflavones; D010946:Plants, Medicinal; D014407:Tumor Cells, Cultured
chemical_list: D004968:Estrogens, Non-Steroidal; D005419:Flavonoids; D007529:Isoflavones; C511898:kwakhurin