Phenytoin poisoning after using Chinese proprietary medicines.
We report a case of poisoning resulting from the use of Chinese proprietary medicines (CPM) containing anticonvulsants phenytoin, carbamazepine and valproate. The manufacturer's information leaflets did not mention any of these prescription drugs. As a consequence, the patient was admitted comatose due to severe phenytoin poisoning. We are not aware of any reported case of severe poisoning due to CPM adulterated with anticonvulsants and this is possibly the first case.
Lau
K K
KK
Department of Medicine and Geriatrics, Princess Margaret Hospital, Kwai Chung, Hong Kong SAR, China.
Lai
C K
CK
Chan
A W
AW
D000328:Adult; D000927:Anticonvulsants / Q000506:poisoning*; D002220:Carbamazepine / Q000506:poisoning; D004338:Drug Combinations; D004340:Drug Contamination; D004365:Drugs, Chinese Herbal / Q000506:poisoning*; D005260:Female; D006801:Humans; D010672:Phenytoin / Q000506:poisoning*; D014635:Valproic Acid / Q000506:poisoning
D000927:Anticonvulsants; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D002220:Carbamazepine; D014635:Valproic Acid; D010672:Phenytoin