Thyroid hormone levels in cord blood of infants with acidemia at birth.
OBJECTIVE
To study the funic thyroid hormone levels in cases were fetal distress during labor resulted in acidemia at birth.


METHODS
Arterial and venous levels of TSH, total T4, free T4 and total T3 obtained from cord blood at birth of twelve acidemic fetuses were compared with normal controls.


RESULTS
Acidemic fetuses had a significanly higher TSH levels than controls (16.5+/-2. 1 microI/dl vs. 9.6+/-1.4 microI/dl, P=0.01). Total T3 levels were significantly lower in acidemic fetuses (49.2+/-2.9 ng/dl vs. 63+/-5. 5 ng/dl, P=0.04). Total and free T4 levels were similar and there was no difference between arterial and venous levels of the hormones.


CONCLUSIONS
Birth acidemia from fetal distress during labor is associated with higher TSH levels and lower T3 levels.
Gemer
O
O
Department of Obstetrics and Gynecology, Barzilai Medical Center, The Faculty of Health Sciences, Ben-Gurion University of the Negev, 78306, Ashkelon, Israel.
Shenhav
S
S
Segal
S
S
Tur-Kaspa
I
I
D000138:Acidosis / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005316:Fetal Distress / Q000097:blood*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D010100:Oxygen / Q000097:blood; D011247:Pregnancy; D013963:Thyroid Hormones / Q000097:blood*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D013963:Thyroid Hormones; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine; D010100:Oxygen