Use of optically active cyclic N,N-dialkyl aminals in asymmetric induction.
[reaction: see text]Cyclization of the optically active ketone N,N-dialkyl aminals A affords the diastereomer B as the major product with diastereoselectivities ranging from nearly 1:1 to essentially 100:0 depending on the cyclization studied.
Jung
M E
ME
Department of Chemistry and Biochemistry, University of California, Los Angeles 90095-1569, USA. jung@chem.ucla.edu
Huang
A
A
D000447:Aldehydes; D003500:Cyclization; D007659:Ketones / Q000737:chemistry*; D013237:Stereoisomerism
D000447:Aldehydes; D007659:Ketones