[Drug and psychological therapies in chronic subjective tinnitus. Meta-analysis of therapeutic effectiveness].
A metaanalysis on pharmacological and psychological treatment reports was conducted in order to evaluate the overall effectiveness of these treatment conditions in chronic tinnitus. A totality of 109 treatment studies published between 1976 and 3/1995 and meeting minimal inclusion criteria was located, but only 24 studies reporting sufficient information could be analyzed. The methodological quality of the studies was evaluated by a coding scheme, and the resulting index of effectiveness has been weighted by this standard as well as by sample size. Effect sizes of pharmacological studies were ES = 1.27 and by this higher than the ones for psychological studies with ES = 0.88. This finding is attenuated by high (unspecific) placebo effects of ES = 0.65 in pharmacological studies compared to ES = 0.10 in psychological studies. In general, patients from psychological studies further improve after treatment in cases where catamnestic measurements have been conducted.
Schilter
B
B
Abteilung Psychosomatik und Psychotherapie, Medizinische Hochschule Hannover.
Jäger
B
B
Heermann
R
R
Lamprecht
F
F
D000779:Anesthetics, Local / Q000009:adverse effects / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D006801:Humans; D008134:Long-Term Care; D011613:Psychotherapy; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D014012:Tinnitus / Q000523:psychology / Q000628:therapy*; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000009:adverse effects / Q000627:therapeutic use*
D000779:Anesthetics, Local; D011619:Psychotropic Drugs; D014665:Vasodilator Agents