title: (S)-4-Methyl-2-(methylamino)pentanoic acid [4, 4-bis(4-fluorophenyl)butyl]amide hydrochloride, a novel calcium channel antagonist, is efficacious in several animal models of pain.
authors.affiliation: Pfizer Global Research and Development, Ann Arbor Laboratories, Pfizer Inc., 2800 Plymouth Road, Ann Arbor, Michigan 48105, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Song
authors.forename: S S
authors.initials: SS
authors.lastname: Bowersox
authors.forename: D T
authors.initials: DT
authors.lastname: Connor
authors.forename: D J
authors.initials: DJ
authors.lastname: Dooley
authors.forename: S M
authors.initials: SM
authors.lastname: Lotarski
authors.forename: T
authors.initials: T
authors.lastname: Malone
authors.forename: G
authors.initials: G
authors.lastname: Miljanich
authors.forename: E
authors.initials: E
authors.lastname: Millerman
authors.forename: M F
authors.initials: MF
authors.lastname: Rafferty
authors.forename: D
authors.initials: D
authors.lastname: Rock
authors.forename: B D
authors.initials: BD
authors.lastname: Roth
authors.forename: J
authors.initials: J
authors.lastname: Schmidt
authors.forename: S
authors.initials: S
authors.lastname: Stoehr
authors.forename: B G
authors.initials: BG
authors.lastname: Szoke
authors.forename: C
authors.initials: C
authors.lastname: Taylor
authors.forename: M
authors.initials: M
authors.lastname: Vartanian
authors.forename: Y X
authors.initials: YX
authors.lastname: Wang
mesh_terms: D000284:Administration, Oral; D018712:Analgesics, Non-Narcotic / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D002121:Calcium Channel Blockers / Q000737:chemistry / Q000494:pharmacology*; D020746:Calcium Channels, L-Type / Q000187:drug effects; D020864:Calcium Channels, N-Type / Q000187:drug effects; D002460:Cell Line; D007275:Injections, Intravenous; D008297:Male; D051379:Mice; D008811:Mice, Inbred DBA; D010147:Pain Measurement; D010421:Pentanoic Acids / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats
chemical_list: C414208:4-methyl-2-(methylamino)pentanoic acid (4, 4-bis(4-fluorophenyl)butyl)amide; D018712:Analgesics, Non-Narcotic; D002121:Calcium Channel Blockers; D020746:Calcium Channels, L-Type; D020864:Calcium Channels, N-Type; D010421:Pentanoic Acids