Proteomics: applications in basic and applied biology.
The rapid evolution of proteomics has continued during the past year, with a series of innovations in the core technologies of two-dimensional electrophoresis and mass spectrometry, and a diversity of productive research programmes. Well-annotated proteomics databases are now emerging in a number of fields to provide a platform for systematic research, with particularly promising progress in clinical applications such as cardiology and oncology. Large-scale quantitative research, comparable in power and sensitivity to that achieved for gene expression, is thus becoming a reality at the protein level.
Anderson
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Large Scale Proteomics Corporation, Rockville, MD 20850, USA.
Matheson
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AD
Steiner
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S
D016208:Databases, Factual; D015180:Electrophoresis, Gel, Two-Dimensional / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods; D008511:Medicine; D008967:Molecular Biology / Q000379:methods* / Q000639:trends; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D014116:Toxicology / Q000639:trends
D011506:Proteins