title: Convenient syntheses of 7-hydroxy-1-(hydroxymethyl)-3-(thymin-1-yl)-2,5-dioxabicyclo
abstract: Synthesis of the diastereoisomeric LNA (locked nucleic acid) nucleosides 1-(2-O,4-C-methylene-alpha-L-ribofuranosyl)thymine (6) and 1-(2-O,4-C-methylene-alpha-L-xylofuranosyl)thymine (13) are reported via convenient reaction cascades from di-O-p-toluenesulfonyl and tri-O-methanesulfonyl nucleoside derivatives 3, 7, and 10.
authors.affiliation: Department of Chemistry, University of Copenhagen, Denmark.
authors.initials: AE
authors.lastname: Hakansson
authors.initials: AA
authors.lastname: Koshkin
authors.initials: MD
authors.lastname: Sorensen
authors.initials: J
authors.lastname: Wengel