How aggressively should blood pressure be treated in renal transplant recipients?
Renal transplantation is the treatment of choice for many patients with endstage renal disease. Patient survival is improved compared with dialysis for all patient ages and racial groups. Renal allograft survival is closely connected with recipient blood pressure. Blood pressure treatment goals that improve patient outcome have been defined for patients with nontransplant renal disease but not for patients with renal transplants. Extrapolating from data from nonrenal transplant patients suggests that aggressive treatment of hypertension in renal transplant patients may improve allograft and patient survival.
Klassen
D K
DK
Division of Nephrology, University of Maryland Medical Systems, 22 S. Greene Street - N3W143, Baltimore, MD 21201, USA. dklassen@medicine.umaryland.edu
D000959:Antihypertensive Agents / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use; D006085:Graft Survival; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000502:physiology; D011184:Postoperative Period; D011507:Proteinuria / Q000503:physiopathology
D000959:Antihypertensive Agents; D007166:Immunosuppressive Agents; D016572:Cyclosporine