Synthetic receptors for CG base pairs.
Hydrogen-bond-mediated complexation of a CG base pair by a hexylureido phthalimide and a hexylureido isoindolin-1-one was studied by (1)H NMR spectroscopy in an organic solvent. Chemical shift data indicate that both receptors effectively bind the CG base pair from the major groove side.
Mertz
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Department of Chemistry, 600 South Mathews Avenue, University of Illinois, Urbana, Illinois 61801, USA.
Mattei
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Zimmerman
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D020029:Base Pairing; D003596:Cytosine / Q000737:chemistry* / Q000378:metabolism; D006147:Guanine / Q000737:chemistry* / Q000378:metabolism; D006860:Hydrogen Bonding; D007211:Indoles / Q000138:chemical synthesis / Q000378:metabolism; D007700:Kinetics; D019906:Nuclear Magnetic Resonance, Biomolecular; D010797:Phthalimides / Q000138:chemical synthesis / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000737:chemistry* / Q000378:metabolism; D012997:Solvents
C033365:DNA receptor; D007211:Indoles; D010797:Phthalimides; D011956:Receptors, Cell Surface; D012997:Solvents; D006147:Guanine; D003596:Cytosine