title: A newborn with nodular ulcerated lesion on a giant congenital nevus.
abstract: The proliferative nodule is a lesion that develops within a congenital nevus. It is usually small (less than 5 mm), sometimes multiple, with a slow growth rate, and has a black or dark brown, smooth, shiny surface. It usually involutes spontaneously. We report a newborn infant who, at birth, had a giant congenital nevus with a nodular, ulcerative, hemorrhagic lesion within it. Physical and neurologic examinations were normal. Radiologic studies at birth and subsequently were normal. A fragment of the lesion was biopsied and histologic findings were compatible with a diagnosis of proliferative nodule in a giant congenital nevus. The rest of the nodule regressed spontaneously after 4 months.
authors.affiliation: Departments of Dermatology, Pathologic Anatomy, and Pediatrics, Hospital General de Mostoles, Madrid, Spain. jborbujom@meditex.es
authors.forename: J
authors.initials: J
authors.lastname: Borbujo
authors.forename: M
authors.initials: M
authors.lastname: Jara
authors.forename: L
authors.initials: L
authors.lastname: Cortes
authors.forename: L
authors.initials: L
authors.lastname: Sanchez de Leon
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006470:Hemorrhage; D006801:Humans; D007231:Infant, Newborn; D009508:Nevus, Pigmented / Q000151:congenital / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000151:congenital / Q000473:pathology*; D012883:Skin Ulcer / Q000473:pathology*