title: Twin-to-twin transfusion syndrome: treatment by amniodrainage and septostomy.
abstract: OBJECTIVE
  Severe previable twin-to-twin transfusion syndrome (TTTS) is associated with a high fetal loss rate and is therefore usually treated. In this paper, serial amniodrainage and inter-twin septostomy are reviewed in terms of technical aspects and fetal outcome.
  
  
  METHODS
  A review of the literature using a MEDLINE DATA search between 1990 and 2000 was done in order to describe the mechanisms and technical aspects of both procedures with their physiopathological consequences. In addition, data from our experience with septostomy are given.
  
  
  RESULTS
  Amniodrainage increases survival rate, with outcome ranging from 40 to 87% (mean: 56%). Inter-twin septostomy is associated with a mean fetal survival rate ranging from 57 to 83% (mean: 70%).
  
  
  CONCLUSIONS
  In severe TTTS, amniodrainage and septostomy are simple therapeutic alternatives with a survival rate similar to what is currently reported for laser coagulation of placental vessels.
authors.affiliation: Department of Obstetrics and Gynaecology, University Hospital Saint-Luc, Université Catholique de Louvain, Avenue Hippocrate 10, B-1200, Brussels, Belgium. hubinont@obst.ucl.ac.be
authors.forename: C
authors.initials: C
authors.lastname: Hubinont
authors.forename: P
authors.initials: P
authors.lastname: Bernard
authors.forename: N
authors.initials: N
authors.lastname: Pirot
authors.forename: J
authors.initials: J
authors.lastname: Biard
authors.forename: J
authors.initials: J
authors.lastname: Donnez
mesh_terms: D000653:Amniotic Fluid; D004322:Drainage; D005260:Female; D005330:Fetofetal Transfusion / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D006801:Humans; D011247:Pregnancy; D015996:Survival Rate; D016216:Ultrasonography, Prenatal / Q000379:methods