title: [Evolution of drug treatments in the aged living at home].
abstract: OBJECTIVE
  Although overprescription and overconsumption of drugs are common in the elderly, their features are still not well known since retrospective data on drug intake in this population is very limited. This study was therefore aimed at assessing the evolution of drug intake in the elderly.
  
  
  METHODS
  In a study undertaken in the context of the PAQUID project, drug intake was assessed in a group of elderly subjects living at home in either Gironde or Dordogne in south-western France. Each subject was visited by an investigator in successively 1988-89, 1991-92, 1993-94, and 1996-97. Three thousand seven hundred and seventy-seven subjects were included in the study since 1988. Their mean age was 75.4 years (CI 95%: 75.2-75.6 years) and the sex ratio was 0.72.
  
  
  RESULTS
  Eighty-nine percent of the subjects took at least one drug per day; 49% took one to four drugs per day; and 40% took more then five drugs per day. The total drug consumption showed an increase in drug intake during the 8-year follow-up, whether the subjects were or not dependent according to their IADL score.
  
  
  CONCLUSIONS
  Analysis of drug intake evolution according to age, sex and daily drug intake at inclusion in the study showed that during follow-up drug intake increased in younger people who had no treatment at study inclusion, while it decreased in older subjects receiving multiple medications. This decrease might be due to either adverse side-effects, drug interactions, or repeated episodes of hospitalization.
authors.affiliation: Service de médecine interne gériatrie, hôpital Xavier-Arnozan, Pessac.
authors.forename: N
authors.initials: N
authors.lastname: Salles-Montaudon
authors.forename: A
authors.initials: A
authors.lastname: Fourrier
authors.forename: J F
authors.initials: JF
authors.lastname: Dartigues
authors.forename: M
authors.initials: M
authors.lastname: Rainfray
authors.forename: J P
authors.initials: JP
authors.lastname: Emeriau
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D004358:Drug Therapy / Q000639:trends*; D005260:Female; D005602:France; D006798:Housing; D006801:Humans; D008297:Male; D012737:Sex Factors