title: [Tissue specificity of subunit composition and EGF-dependent changes in the subunit pattern of 20S-proteasomes].
abstract: The subunit pattern of 20S proteasomes from rat kidney, rat liver, human A-431 cells, human K-562 cells and mouse NIH 3T3 cells were studied. Proteasomes in cells of a common tissue origin appeared to be similar, independently of the intensity of cell proliferation. Unlike, proteasomes in cells of various types of tissue specificity differed from each other. Besides, EGF was shown to induce changes in the subunit pattern of proteasomes in A-431 cells.
authors.affiliation: Institute of Cytology RAS, St. Petersburg. ikonst@mail.cytspb.rssi.ru
authors.forename: I M
authors.initials: IM
authors.lastname: Konstantinova
authors.forename: I V
authors.initials: IV
authors.lastname: Volkova
authors.forename: A L
authors.initials: AL
authors.lastname: Evdonin
authors.forename: Iu B
authors.initials: IuB
authors.lastname: Ermolaeva
authors.forename: V A
authors.initials: VA
authors.lastname: Kulichkova
authors.forename: A S
authors.initials: AS
authors.lastname: Kuz'minova
authors.forename: N D
authors.initials: ND
authors.lastname: Medvedeva
mesh_terms: D016475:3T3 Cells; D000818:Animals; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D006801:Humans; D051379:Mice; D009097:Multienzyme Complexes / Q000378:metabolism*; D009928:Organ Specificity; D046988:Proteasome Endopeptidase Complex; D051381:Rats
chemical_list: D009097:Multienzyme Complexes; D004815:Epidermal Growth Factor; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex