Acquired hemophilia successfully treated with oral immunosuppressive therapy.
Acquired hemophilia is a rare disorder associated with serious bleeding in nonhemophilic patients. We had a 40-year-old woman who was diagnosed as acquired hemophilia with a factor VIII inhibitor level of 27.5 BU/mL. She was presented with gross hematuria and severe right shoulder pain, and was successfully treated with daily oral cyclophosphamide and prednisone for 2 weeks. After the remission, the doses of prednisone and cyclophosphamide were slowly decreased and she remained in complete remission without further bleeding episodes.
Lee
J J
JJ
Department of Internal Medicine and Clinical Pathology, Chonnam National University Medical School, Kwangju, Korea.
Chung
I J
IJ
Park
M R
MR
Yang
D H
DH
Cho
S H
SH
Ryang
D W
DW
Kim
H J
HJ
D000284:Administration, Oral; D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use*; D005260:Female; D006467:Hemophilia A / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D011241:Prednisone / Q000627:therapeutic use*
D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011241:Prednisone