[The use of oxytocin in the combined treatment of suppurative-necrotic lesions of the feet in diabetic patients].
The results of treatment of 90 patients with diabetes mellitus and pyo-necrotic lesions of the feet were compared. Oxytocin was used in 40 of the patients. It was found that parenteral administration of oxytocin resulted in more favorable course of diabetes mellitus in such patients. The intra-arterial or local use of Oxytocin was found to reliably increase the DNA synthesis by the endothelial cells, fibroblasts and histiocytes, which in its turn creates favorable conditions for the reparative process in the wounds and allows quality of the treatment to be considerably improved.
Gavrilenko
V G
VG
Stadnikov
A A
AA
Esipov
V K
VK
Mit'kin
A F
AF
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D003131:Combined Modality Therapy; D004247:DNA / Q000096:biosynthesis / Q000187:drug effects; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D017719:Diabetic Foot / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D005528:Foot / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010121:Oxytocin / Q000627:therapeutic use*
D010121:Oxytocin; D004247:DNA