Evaluation of two slide agglutination tests and a novel immunochromatographic assay for rapid diagnosis of infectious mononucleosis.
The results of three tests used for the rapid diagnosis of infectious mononucleosis (IM) were compared with those of Epstein-Barr virus-specific serology. The sensitivities ranged from 15 to 33% in children under 13 years of age and from 59 to 81% in patients over 13 years. The specificities ranged from 86 to 100% in both age groups. These tests have a poor sensitivity for the diagnosis of IM, particularly in children.
Gómez
M C
MC
Microbiology Laboratory, Hospital "Virgen de la Luz," Cuenca, Spain. anaglo@santandersupernet.com
Nieto
J A
JA
Escribano
M A
MA
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000372:Agglutination Tests / Q000379:methods*; D000818:Animals; D000910:Antibodies, Heterophile / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D002417:Cattle; D002648:Child; D002675:Child, Preschool; D002846:Chromatography, Affinity / Q000379:methods*; D019309:Epstein-Barr Virus Nuclear Antigens / Q000276:immunology; D005260:Female; D006168:Guinea Pigs; D004854:Herpesvirus 4, Human / Q000276:immunology; D006736:Horses; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D007223:Infant; D007244:Infectious Mononucleosis / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011933:Reagent Kits, Diagnostic; D013997:Time Factors
D000910:Antibodies, Heterophile; D000914:Antibodies, Viral; D019309:Epstein-Barr Virus Nuclear Antigens; D007075:Immunoglobulin M; D011933:Reagent Kits, Diagnostic