[Tissue specificity of subunit composition and EGF-dependent changes in the subunit pattern of 20S-proteasomes].
The subunit pattern of 20S proteasomes from rat kidney, rat liver, human A-431 cells, human K-562 cells and mouse NIH 3T3 cells were studied. Proteasomes in cells of a common tissue origin appeared to be similar, independently of the intensity of cell proliferation. Unlike, proteasomes in cells of various types of tissue specificity differed from each other. Besides, EGF was shown to induce changes in the subunit pattern of proteasomes in A-431 cells.
Konstantinova
I M
IM
Institute of Cytology RAS, St. Petersburg. ikonst@mail.cytspb.rssi.ru
Volkova
I V
IV
Evdonin
A L
AL
Ermolaeva
Iu B
IuB
Kulichkova
V A
VA
Kuz'minova
A S
AS
Medvedeva
N D
ND
D016475:3T3 Cells; D000818:Animals; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D006801:Humans; D051379:Mice; D009097:Multienzyme Complexes / Q000378:metabolism*; D009928:Organ Specificity; D046988:Proteasome Endopeptidase Complex; D051381:Rats
D009097:Multienzyme Complexes; D004815:Epidermal Growth Factor; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex