Elevated basal activity of tryptophan oxygenase in alcohol-preferring C57BL mice.
Tryptophan oxygenase activity in alcohol-preferring C57Bl mice and control CBA and DBA/2 mice was studied under nonstressful conditions and after glucocorticoid-induced stress. Elevated basal tryptophan oxygenase activity in C57Bl mice is probably responsible for reduced brain content of tryptophan and serotonin associated with alcohol preference.
Vasil'eva
E D
ED
Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk.
Yakovleva
T V
TV
Il'nitskaya
S I
SI
Vasil'ev
G V
GV
D000437:Alcoholism / Q000097:blood / Q000201:enzymology*; D000818:Animals; D015415:Biomarkers; D051379:Mice; D008810:Mice, Inbred C57BL; D014366:Tryptophan Oxygenase / Q000097:blood*
D015415:Biomarkers; D014366:Tryptophan Oxygenase