title: Response of laryngeal airway resistance to chemoreceptor stimulation: effect of pulmonary afferent denervation.
abstract: The response of laryngeal airway resistance to chemoreceptor stimulation was measured before and after vagotomy in ten anesthetized dogs. With the vagus nerves intact, stimulation of chemoreceptors produced a decrease in both inspiratory and expiratory laryngeal resistance. After bilateral vagotomy below the origin of the recurrent laryngeal nerves, stimulation of chemoreceptors produced a smaller decrease in inspiratory laryngeal resistance and an increase in expiratory laryngeal resistance. We concluded that pulmonary afferent input to the respiratory neurons maintains a low airway resistance during chemoreceptor stimulation.
authors.affiliation: Department of Otorhinolaryngology, Mayo Clinic, Rochester, Minn., USA.
authors.forename: T V
authors.initials: TV
authors.lastname: McCaffrey
mesh_terms: D000344:Afferent Pathways / Q000503:physiopathology; D000403:Airway Resistance / Q000502:physiology*; D000818:Animals; D002628:Chemoreceptor Cells / Q000503:physiopathology*; D003714:Denervation; D004285:Dogs; D007830:Larynx / Q000503:physiopathology*; D008168:Lung / Q000294:innervation*; D012966:Sodium Cyanide; D013268:Stimulation, Chemical; D014630:Vagus Nerve / Q000503:physiopathology*
chemical_list: D012966:Sodium Cyanide