The microstructure of ethanol drinking: genetic and behavioral factors in the control of drinking patterns.
The concept of craving can be examined in many different ways, depending upon the individual definition of the term. Using the concepts and procedures of regulatory behavior analysis, this review explores behavioral studies in rats that have some relationships to some of the possible processes that underlie the concept of craving in humans. Data are reviewed from studies employing both limited and continuous access to ethanol, examining the role of access availability, ethanol initiation, response cost, time since last access, composition of the ethanol containing solution and genetic selection. From this review, it is clear that rat models can implicate important variables involved in the control of human alcohol consumption.
Samson
H H
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Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1083, USA. samson@wfubmc.edu
D000428:Alcohol Drinking / Q000235:genetics* / Q000523:psychology; D000818:Animals; D016739:Behavior, Addictive / Q000235:genetics* / Q000523:psychology; D001947:Breeding; D003216:Conditioning, Operant; D018565:Food-Drug Interactions; D051381:Rats; D011917:Rats, Inbred Lew; D020318:Rats, Long-Evans; D012107:Research Design