title: [Relation between retinal pigment epithelial detachment and dye leakage in central serous retinopathy].
abstract: OBJECTIVE
  The purpose of this report is to provide supportive evidence favoring the hypothesis of choroidal hyperpermeability in central serous chorioretinopathy.
  
  
  METHODS
  Seven consecutive patients (eight eyes) with a history of central serous chorioretinopathy were explored. Fluorescein angiography and a monochromatic frame at 640 mm was performed for all eyes. All showed dye leakage located at the rim of a retinal pigment epithelial detachment.
  
  
  RESULTS
  Retinal pigment epithelial detachment was extrafoveal in all 8 eyes. Dye leakage was located at the nasal rim in 4 eyes, the superior rim in 2 eyes, the temporal rim in 1 and the anterior rim in the last eye.
  
  
  CONCLUSIONS
  Dye leakage at the rim of pigment epithelial detachment in central serous chorioretinopathy is a strong argument for the hypothesis of a choroidal hyperpermeability. The hyperpressure crushes the overlying retinal pigment epithelium and in some areas provokes focal detachment and dye leakage at the junction of the detached and attached pigment epithelium.
authors.affiliation: Service d'Ophtalmologie, Hôpital Huriez, 2, avenue Oscar Lambret, 59037 Lille Cedex, France.
authors.forename: G
authors.initials: G
authors.lastname: Constantinides
mesh_terms: D000328:Adult; D015862:Choroid Diseases / Q000150:complications* / Q000175:diagnosis; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000175:diagnosis* / Q000209:etiology; D012164:Retinal Diseases / Q000150:complications / Q000175:diagnosis; D014792:Visual Acuity