title: Effect of hip prostheses on radiotherapy dose.
abstract: A small but growing proportion of patients requiring radiotherapy for prostate cancer have one or two hip prostheses which may shadow the target and affect the dose distribution. Approximately 10 such patients are treated at the Illawarra Cancer Care Centre per year. Hence a study was undertaken to examine the accuracy of various treatment methods that involve some of the treatment fields travelling through the prosthesis. A fixed-field measurement showed a dose reduction of 52% in the shadow of the prosthesis. A Monte Carlo simulation confirmed an increase in dose on the distal surface of the prosthesis of 35%. Of more clinical relevance, however, is the dose distribution due to the overall combined field treatment. Using a power law correction benchmarked against thermoluminescent dosimeters and Gafchromic film, three different beam set-ups for patient treatment were planned and the dose variation analysed. A four-field brick technique gave a dose variation across the target volume of +/- 15% whereas a dual arc technique gave a dose variation of only +/- 5%. A four-field oblique technique gave a dose variation of only +/- 2% across the target volume but the oblique field technique included extra dose to the rectum.
authors.affiliation: Illawarra Cancer Care Centre, Wollongong, New South Wales, Australia.
authors.forename: M
authors.initials: M
authors.lastname: Carolan
authors.forename: P
authors.initials: P
authors.lastname: Dao
authors.forename: C
authors.initials: C
authors.lastname: Fox
authors.forename: P
authors.initials: P
authors.lastname: Metcalfe
mesh_terms: D001672:Biocompatible Materials; D003198:Computer Simulation; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D019047:Phantoms, Imaging; D011471:Prostatic Neoplasms / Q000532:radiotherapy; D011474:Prosthesis Design; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D015203:Reproducibility of Results; D013819:Thermoluminescent Dosimetry; D014800:Vitallium
chemical_list: D001672:Biocompatible Materials; D014800:Vitallium