title: Hemolytic-uremic syndrome as a presenting form of acute lymphocytic leukemia.
abstract: We report an 8-year-old girl who presented with hemolytic-uremic syndrome (HUS) as the onset manifestation of acute lymphocytic leukemia (ALL). The patient was admitted to the hospital for renal failure, thrombocytopenia, and anemia during a HUS outbreak. She was discharged 2 weeks later with normal renal function. One month later the girl presented with clinical and laboratory signs consistent with a diagnosis of ALL. The short time interval between HUS and ALL suggests that HUS was probably an early manifestation of acute leukemia.
authors.affiliation: Department of Pediatrics, University of Padova, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Martini
authors.forename: R
authors.initials: R
authors.lastname: Dall'Amico
authors.forename: L
authors.initials: L
authors.lastname: Murer
authors.forename: G
authors.initials: G
authors.lastname: Montini
authors.forename: A
authors.initials: A
authors.lastname: D'Avino
authors.forename: G
authors.initials: G
authors.lastname: Zacchello
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D004196:Disease Outbreaks; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis*