title: Enhanced reactivity of electron-deficient enynes in the palladium-catalyzed homo-benzannulation of conjugated enynes
abstract: We report the high reactivity of electron-deficient enynes in the homo-benzannulation of conjugated enynes in the presence of Pd(PPh3)4. The introduction of electron-withdrawing groups enabled us to carry out the benzannulation of 1-substituted enynes as well as 1,2- and 2,4-disubstituted enynes. Polysubstituted benzenes were prepared in a highly regioselective manner in good to excellent yields.
authors.affiliation: Institute for Chemical Reaction Science, Tohoku University, Sendai, Japan.
authors.initials: S
authors.lastname: Saito
authors.initials: Y
authors.lastname: Chounan
authors.initials: T
authors.lastname: Nogami
authors.initials: T
authors.lastname: Fukushi
authors.initials: N
authors.lastname: Tsuboya
authors.initials: Y
authors.lastname: Yamada
authors.initials: H
authors.lastname: Kitahara
authors.initials: Y
authors.lastname: Yamamoto