title: [Assessment of the risk of radiation-induced leukaemia in the vicinity of nuclear installations: the Nord-Cotentin radio-ecological study].
abstract: BACKGROUND
  A radioecological study has been launched in 1997 to perform a realistic assessment of radiation doses received by the population aged 0 to 24 years who lived in the vicinity of the La-Hague nuclear reprocessing plant (Nord-Cotentin, France), and to estimate the associated risk of leukaemia between 1978 and 1996.
  
  
  METHODS
  The Working Group in charge of the study included representatives of French radiation protection institutes, nuclear operators, members of environmental organisations and international experts. The methodology retained developed three steps
  
  
  RESULTS
  The reconstructed cohort included 6656 individuals born between 1954 and 1996, who lived in the study area for at least one year between 1978 and 1996 before the age of 25. The number of person-years between 1978 and 1996 is 69 308. On the basis of the calculated doses, the estimated number of radiation-induced leukaemia attributable to releases from local nuclear installations was less than 0.002 for the period 1978-1996.
  
  
  CONCLUSIONS
  This result constitutes a best estimate of the risk of radiation-induced leukaemia among young people in the canton of Beaumont-Hague. Nevertheless, this estimation must be interpreted in the light of the limits inherent to the risk assessment process and some participants of the Working Group expressed some reservations. The estimated number of radiation-induced leukaemia attributable to local nuclear installations is low in comparison to the 4 cases of leukaemia observed by epidemiological studies during the same period. It is therefore very unlikely that releases from local nuclear installations could notably explain the high incidence of leukaemia observed among young people in the canton of Beaumont-Hague.
authors.affiliation: Institut de Protection et de Sûreté Nucléaire, Département de Protection de la santé de l'Homme et de Dosimétrie, Service d'Evaluation et de Gestion des Risques. B.P.6, F-92265 Fontenay-aux-Roses Cedex.
authors.forename: D
authors.initials: D
authors.lastname: Laurier
authors.forename: C
authors.initials: C
authors.lastname: Rommens
authors.forename: C
authors.initials: C
authors.lastname: Drombry-Ringeard
authors.forename: A
authors.initials: A
authors.lastname: Merle-Szeremeta
authors.forename: J
authors.initials: J
authors.lastname: Degrange
mesh_terms: D000293:Adolescent; D000328:Adult; D001417:Background Radiation; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004781:Environmental Exposure; D005602:France / Q000453:epidemiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007953:Leukemia, Radiation-Induced / Q000453:epidemiology*; D008954:Models, Biological; D009678:Nuclear Energy; D011210:Power Plants; D011829:Radiation Dosage; D011847:Radioactive Fallout; D018788:Radioactive Hazard Release; D018570:Risk Assessment
chemical_list: D011847:Radioactive Fallout