title: Modifier genes of hereditary hearing loss.
abstract: Phenotypic variation between individuals with the same disease alleles may be attributable to the genotype at another locus, which is referred to as a modifier gene. Recent functional studies of modifier genes of hearing-loss loci have begun to refine our understanding of hearing processes and will guide the rational design of medical therapies for hearing loss.
authors.affiliation: Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, Rockville, Maryland 20850, USA. friedman@nihcd.nih.gov
authors.forename: T
authors.initials: T
authors.lastname: Friedman
authors.forename: J
authors.initials: J
authors.lastname: Battey
authors.forename: B
authors.initials: B
authors.lastname: Kachar
authors.forename: S
authors.initials: S
authors.lastname: Riazuddin
authors.forename: K
authors.initials: K
authors.lastname: Noben-Trauth
authors.forename: A
authors.initials: A
authors.lastname: Griffith
authors.forename: E
authors.initials: E
authors.lastname: Wilcox
mesh_terms: D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D003638:Deafness / Q000235:genetics*; D005820:Genetic Testing / Q000379:methods*; D005838:Genotype; D006198:Hair Cells, Auditory / Q000502:physiology* / Q000648:ultrastructure; D006801:Humans; D009154:Mutation / Q000235:genetics*; D010641:Phenotype