title: The Arabidopsis SUCROSE UNCOUPLED-6 gene is identical to ABSCISIC ACID INSENSITIVE-4: involvement of abscisic acid in sugar responses.
abstract: In plants, sugars act as signalling molecules that control many aspects of metabolism and development. Arabidopsis plants homozygous for the recessive sucrose uncoupled-6 (sun6) mutation show a reduced sensitivity to sugars for processes such as photosynthesis, gene expression and germination. The sun6 mutant is insensitive to sugars that are substrates for hexokinase, suggesting that SUN6 might play a role in hexokinase-dependent sugar responses. The SUN6 gene was cloned by transposon tagging and analysis showed it to be identical to the previously described ABSCISIC ACID INSENSITIVE-4 (ABI4) gene. Our analysis suggests the involvement of abscisic acid and components of the abscisic acid signal transduction cascade in a hexokinase-dependent sugar response pathway. During the plant life cycle, SUN6/ABI4 may be involved in controlling metabolite availability in an abscisic acid- and sugar-dependent way.
authors.affiliation: Department of Molecular Plant Physiology and; Department of Molecular Genetics, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.
authors.forename: C
authors.initials: C
authors.lastname: Huijser
authors.forename: A
authors.initials: A
authors.lastname: Kortstee
authors.forename: J
authors.initials: J
authors.lastname: Pego
authors.forename: P
authors.initials: P
authors.lastname: Weisbeek
authors.forename: E
authors.initials: E
authors.lastname: Wisman
authors.forename: S
authors.initials: S
authors.lastname: Smeekens
mesh_terms: D000040:Abscisic Acid / Q000502:physiology*; D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism*; D050260:Carbohydrate Metabolism; D017343:Genes, Plant; D006720:Homozygote; D015398:Signal Transduction
chemical_list: D000040:Abscisic Acid