title: Ovarian ependymoma. A case report.
abstract: We present the case of a 30-year-old woman who was referred to our institution with an erroneous diagnosis of poorly differentiated carcinoma of the ovary. The patient presented pelvic pain for one year prior to surgery. A second laparotomy revealed a bilateral pure ovarian ependymoma that infiltrated the uterus and presented implants on the omentum. Differential diagnosis included mainly endometrioid and small cell carcinoma of the ovary. Presence of typical ependymal rosettes and positivity to GFAP confirmed the diagnosis of ependymoma. Other teratomatous elements were not observed. Ovarian ependymomas are rare tumors; only eight cases, to our knowledge, have been reported in the literature. They have a favorable prognosis; patients with advanced stage disease are reported alive and well after treatment with surgery and chemotherapy.
authors.affiliation: Instituto Anatomopatológico Dr. Jose A. O'Daly, Universidad Central de Venezuela, Sabana Grande, Caracas.
authors.forename: V
authors.initials: V
authors.lastname: Garcia-Barriola
authors.forename: M N
authors.initials: MN
authors.lastname: De Gómez
authors.forename: J A
authors.initials: JA
authors.lastname: Suárez
authors.forename: C
authors.initials: C
authors.lastname: Lara
authors.forename: J E
authors.initials: JE
authors.lastname: González
authors.forename: J
authors.initials: J
authors.lastname: García-Tamayo
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D004806:Ependymoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D006801:Humans; D009361:Neoplasm Invasiveness; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
chemical_list: D005904:Glial Fibrillary Acidic Protein