Common variable immunodeficiency (CVID) and inclusion body myositis (IBM).
A case of a 38-year old man with a common variable immunodeficiency syndrome (CVID) is demonstrated who suffered at the same time from a histologically proven inclusion body myositis (IBM). The myositis did not resolve after institution of regular intravenous IgG infusions. This case demonstrates a very long lasting benign course of IBM. The occurrence with CVID may be a clinical hint for a viral pathogenesis of IBM. So far only two similar cases are reported in the literature.
Gause
A
A
Poliklinik für Rheumatologie, Universitätsklinikum Lübeck und Krankenhausabteilung der Rheumaklinik Bad Bramstedt, Germany. a.gause@rheuma-zentrum.de
Inderrieden
D C
DC
Laas
R
R
Arlt
A C
AC
Gross
W L
WL
D000328:Adult; D018771:Arthralgia / Q000150:complications / Q000503:physiopathology; D001379:Azathioprine / Q000627:therapeutic use; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D005221:Fatigue / Q000150:complications / Q000503:physiopathology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male; D018979:Myositis, Inclusion Body / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D011239:Prednisolone / Q000627:therapeutic use; D013717:Tenosynovitis / Q000150:complications / Q000503:physiopathology; D005719:gamma-Globulins / Q000627:therapeutic use
D016756:Immunoglobulins, Intravenous; D005719:gamma-Globulins; D011239:Prednisolone; D001379:Azathioprine