[New look on pathology of multiple sclerosis?].
Recent studies made using immunohistochemistry, three dimensional imaging in confocal microscopy and magnetic resonance spectroscopy testified that, not only demyelination, but also axonal damage occur already in early phase of multiple sclerosis. There exists the direct correlation between axonal changes and chronic disability of the patients. The results indicate the need for intensive treatment of multiple sclerosis as early as definite diagnosis is made.
Wender
M
M
Zespołu Neuroimmunologicznego, Instytutu Centrum Medycyny Doświadczalnej i Klinicznej PAN w Poznaniu.
D001921:Brain / Q000473:pathology*; D002908:Chronic Disease; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000175:diagnosis*