Magnetic resonance imaging of a non-pigmented adenoma of the ciliary epithelium.
OBJECTIVE
A non-pigmented adenoma of the ciliary epithelium is rare. No good documentation has been reported in which magnetic resonance imaging (MRI), histological examination, and immunohistological evaluation have all been conducted. We showed how this tumor differed from ciliary body melanoma.


METHODS
We evaluated the ciliary body tumor by MRI, histological examination, and immunohistochemical examination. The data was compared with previously reported cases.


RESULTS
The tumor was classified as an adenoma of the non-pigmented ciliary epithelium with extracellular pools of hyaluronidase-sensitive mucopolysaccharide. The MRI appearance of the vitreous in our patient showed hyperintensity on T1, isointensity on T2 and marked enhancement with gadolinium. None of 3 other reported patients exhibited the same signals.


CONCLUSIONS
MRI appearance is most variable in adenomas and no microscopical diagnosis can be based on that. Our patient showed isointensity on T2 with marked enhancement by gadolinium when compared to malignant melanoma.
Nakazawa
T
T
Department of Ophthalmology, Yamagata City Hospital, Japan. ntoru@fa2.so-net.ne.jp
Abe
T
T
Sato
Y
Y
Yuda
F
F
Omura
M
M
Tamai
M
M
D000236:Adenoma / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D000951:Antigens, Neoplasm; D002924:Ciliary Body / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005451:Fluorescein Angiography; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D058950:Melanoma-Specific Antigens; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000378:metabolism; D010751:Phosphopyruvate Hydratase / Q000378:metabolism; D010857:Pigment Epithelium of Eye / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D009418:S100 Proteins / Q000378:metabolism; D014604:Uveal Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery
D000951:Antigens, Neoplasm; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins; D009418:S100 Proteins; D010751:Phosphopyruvate Hydratase