Evaluation of thyroid function in dogs suffering from recurrent flank alopecia.
Thyroid function was assessed in euthyroid dogs (n = 20), dogs suffering from canine recurrent flank alopecia (CRFA, n = 18), and hypothyroid dogs (n = 21). Blood samples obtained from all dogs in each group were assayed for total thyroxine (TT4), thyrotropin (TSH), and thyroglobulin autoantibody (TgAA) serum concentrations. Total T4 and TSH serum concentrations were significantly decreased and increased, respectively, in the hypothyroid group compared with the other 2 groups. No significant differences in TT4 and TSH serum values were found between the euthyroid and CRFA groups. Thyroglobulin autoantibodies were detected in 10, 11.1, and 61.9% of euthyroid dogs, dogs with CRFA, and hypothyroid dogs, respectively. In conclusion, dogs suffering from CRFA have a normal thyroid function, and the determination of TT4 and TSH serum concentrations allows differentiation of these dogs from dogs with hypothyroidism, in most cases. Occasionally, the 2 diseases can be concomitant.
Daminet
S
S
Département de sciences cliniques, Faculté de médecine vétérinaire, Université de Montréal, Québec.
Paradis
M
M
D000505:Alopecia / Q000209:etiology / Q000662:veterinary*; D000818:Animals; D001323:Autoantibodies / Q000032:analysis; D004285:Dogs; D005260:Female; D007037:Hypothyroidism / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D008297:Male; D013960:Thyroid Function Tests / Q000662:veterinary; D013963:Thyroid Hormones / Q000032:analysis
D001323:Autoantibodies; D013963:Thyroid Hormones