title: Hierarchical state space partitioning with a network self-organising map for the recognition of ST-T segment changes.
abstract: The problem of maximising the performance of ST-T segment automatic recognition for ischaemia detection is a difficult pattern classification problem. The paper proposes the network self-organising map (NetSOM) model as an enhancement to the Kohonen self-organised map (SOM) model. This model is capable of effectively decomposing complex large-scale pattern classification problems into a number of partitions, each of which is more manageable with a local classification device. The NetSOM attempts to generalize the regularization and ordering potential of the basic SOM from the space of vectors to the space of approximating functions. It becomes a device for the ordering of local experts (i.e. independent neural networks) over its lattice of neurons and for their selection and co-ordination. Each local expert is an independent neural network that is trained and activated under the control of the NetSOM. This method is evaluated with examples from the European ST-T database. The first results obtained after the application of NetSOM to ST-T segment change recognition show a significant improvement in the performance compared with that obtained with monolithic approaches, i.e. with single network types. The basic SOM model has attained an average ischaemic beat sensitivity of 73.6% and an average ischaemic beat predictivity of 68.3%. The work reports and discusses the improvements that have been obtained from the implementation of a NetSOM classification system with both multilayer perceptrons and radial basis function (RBF) networks as local experts for the ST-T segment change problem. Specifically, the NetSOM with multilayer perceptrons (radial basis functions) as local experts has improved the results over the basic SOM to an average ischaemic beat sensitivity of 75.9% (77.7%) and an average ischaemic beat predictivity of 72.5% (74.1%).
authors.affiliation: Department of Medical Physics, School of Medicine, University of Patras, Greece. bezer@patreas.upatras.gr
authors.forename: A
authors.initials: A
authors.lastname: Bezerianos
authors.forename: L
authors.initials: L
authors.lastname: Vladutu
authors.forename: S
authors.initials: S
authors.lastname: Papadimitriou
mesh_terms: D004562:Electrocardiography / Q000379:methods*; D006801:Humans; D008955:Models, Cardiovascular; D017202:Myocardial Ischemia / Q000175:diagnosis*; D016571:Neural Networks, Computer; D012815:Signal Processing, Computer-Assisted