Prognostic implications of myocardial contractile reserve in patients with ischemic cardiomyopathy.
The extent and degree of myocardial viability is an important parameter in the risk stratification of patients with significant left ventricular dysfunction due to coronary artery disease (CAD). Although several imaging modalities can identify viable myocardium, dobutamine stress echocardiography has gained considerable importance as an accurate, safe, and reliable method. In patients with significant left ventricular dysfunction secondary to CAD, identifying the presence and extent of contractile reserve and, therefore, viable myocardium, during low dose dobutamine infusion can predict recovery of left ventricular function postrevascularization, survival, and future cardiac events.
Galatro
K
K
Hahnemann University Hospital, Division of Cardiology, Broad and Vine, M.S. 313, Philadelphia, PA 19102, USA.
Chaudhry
F A
FA
D002316:Cardiotonic Agents / Q000008:administration & dosage; D004280:Dobutamine / Q000008:administration & dosage; D004452:Echocardiography / Q000379:methods*; D005080:Exercise Test; D006801:Humans; D007262:Infusions, Intravenous; D009200:Myocardial Contraction / Q000502:physiology*; D017202:Myocardial Ischemia / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011379:Prognosis; D015203:Reproducibility of Results; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology
D002316:Cardiotonic Agents; D004280:Dobutamine