title: Intraperitoneal tonometry for detection of regional enteric ischaemia.
abstract: BACKGROUND
  The objective of this study was to test the hypothesis that intraperitoneal tonometry can be a specific monitor for ischaemia in the small intestine.
  
  
  METHODS
  Twelve pigs were anaesthetized and mechanically ventilated. The celiac artery (CA), the superior mesenteric artery (SMA) and the inferior mesenteric artery (IMA) were identified. Tonometry catheters were positioned intraperitoneally at three different locations where blood supply varied. One at a time of the mesenteric arteries was occluded, producing regional ischaemia in different splanchnic organs.
  
  
  RESULTS
  Regional PCO2 (Pr CO2) increased significantly in the intestinal region, in the small intestine, only during the SMA clamping. In the epigastric region, i.e. in the space between the liver and the stomach, PrCO2 increased significantly only during CA clamping.
  
  
  CONCLUSIONS
  Intraperitoneal tonometry in the intestinal region can be a specific monitor of ischaemia in the small intestine.
  
  
  METHODS
  The care and handling of the animals was in accordance with legislation by the Swedish Board of Agriculture.
authors.affiliation: Department of Anaesthesiology and Intensive Care, Uppsala University Hospital, Sweden.
authors.forename: I
authors.initials: I
authors.lastname: Koga
authors.forename: H
authors.initials: H
authors.lastname: Stiernstrom
authors.forename: L
authors.initials: L
authors.lastname: Christiansson
authors.forename: L
authors.initials: L
authors.lastname: Wiklund
mesh_terms: D000758:Anesthesia; D000818:Animals; D001784:Blood Gas Analysis; D002404:Catheterization; D005260:Female; D007410:Intestinal Diseases / Q000175:diagnosis*; D007421:Intestine, Small / Q000098:blood supply*; D007511:Ischemia / Q000175:diagnosis*; D008297:Male; D010537:Peritoneum; D012039:Regional Blood Flow / Q000502:physiology; D015656:Respiratory Mechanics; D013552:Swine; D014065:Tonometry, Ocular