Vitamin E and C in preeclampsia.
Vascular endothelial damage has been implicated in the pathophysiology of preeclampsia. Lipid peroxidation may be involved in the process and essential nutrients that can scavenge free radicals, such as vitamin E and C, operate in concert. Antioxidant vitamins E and C were estimated in 30 preeclamptic and 30 normotensive pregnant women. Significantly lowered levels of vitamins E and C were observed in preeclamptic women as compared to controls (P<0.001 and P<0.05 respectively). In patients with preeclampsia antioxidant nutrients may be utilized to a greater extent to counteract free radical-mediated cell disturbances, resulting in a reduction in serum antioxidant levels.
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Department of Biochemistry, Pt. B.D. Sharma PGIMS, Rohtak, India.
D000293:Adolescent; D000328:Adult; D000975:Antioxidants / Q000378:metabolism; D001205:Ascorbic Acid / Q000097:blood*; D001724:Birth Weight; D001794:Blood Pressure; D036861:Delivery, Obstetric; D005260:Female; D005865:Gestational Age; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011507:Proteinuria; D014810:Vitamin E / Q000097:blood*
D000975:Antioxidants; D014810:Vitamin E; D001205:Ascorbic Acid