Myoepithelial carcinoma of the lung arising from bronchial submucosa.
Myoepithelial neoplasm mainly occurs in the salivary glands and breasts and is extremely rare in the lung. To our knowledge, this report describes the first documented case of a myoepithelial carcinoma present in the lung. The tumor derived from the right main bronchial submucosa and exhibited a dual epithelial and smooth muscular phenotype by immunohistochemical and ultrastructural studies. It invaded the neighboring pulmonary tissue and the hilar lymph nodes. Despite a right pneumonectomy and chemotherapy, metastasis was found in the left lung 7 months later.
Miura
K
K
Division of Pathology, Hamamatsu University School of Medicine, Japan. kmiura@hama-med.ac.jp
Harada
H
H
Aiba
S
S
Tsutsui
Y
Y
D001984:Bronchial Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000556:secondary / Q000648:ultrastructure; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009208:Myoepithelioma / Q000473:pathology* / Q000648:ultrastructure; D009361:Neoplasm Invasiveness; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000648:ultrastructure