Rosai-Dorfman disease of the larynx.
We present a case of an 81-year-old man with a history of worsening dysphonia of six months duration. A year before a sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) was diagnosed on a submandibular lymph node biopsy. On presentation the patient showed a mass in the left subglottic area with a modest reduction in the airway space. The patient underwent an endoscopic CO2 laser excision of the mass, without post-operative complications. Histopathological examination and electron microscope images confirmed the previous diagnosis of Rosai-Dorfman disease. The clinical and pathological features of this entity are discussed.
Aluffi
P
P
Department of Otorhinolaryngology, University of Piemonte Orientale, Novara, Italy.
Prestinari
A
A
Ramponi
A
A
Castri
M
M
Pia
F
F
D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D015618:Histiocytosis, Sinus / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007828:Laryngoscopy / Q000379:methods; D008297:Male; D008854:Microscopy, Electron; D014057:Tomography, X-Ray Computed