title: The renin-angiotensin system antagonism in the treatment of hypertension.
abstract: The effective treatment of hypertension is associated with improved mortality and morbidity from diseases such as stroke, congestive heart failure, and renal failure. Use of medications that target the renin-angiotensin system for the treatment of hypertension can often achieve the desired decrease in blood pressure while causing a minimum of unwanted side effects. In this paper, the principles of the renin-angiotensin system antagonism are described. The approach to using these medications is discussed with special attention to specific indications as well as common side effects.
authors.affiliation: Divisions of Hypertension and Cardiology, University of Michigan Medical Center, 3918 Taubman Center, Box 0356, Ann Arbor, Michigan 48109, USA.
authors.forename: J D
authors.initials: JD
authors.lastname: Bisognano
authors.forename: R J
authors.initials: RJ
authors.lastname: Cody
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology*; D012084:Renin-Angiotensin System / Q000187:drug effects* / Q000502:physiology
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents