Occurrence of scleroderma in monozygotic twins.
Familial occurrence of scleroderma is rare and concordance for the disease in twins has been reported exceptionally. We describe 2 female identical twin pairs concordant for scleroderma. The first twin pair was diagnosed with the systemic form of scleroderma, the second pair with the localized form.
De Keyser
F
F
Department of Rheumatology and the Center of Medical Genetics, University Hospital Gent, Belgium. filip.dekeyser@rug.ac.be
Peene
I
I
Joos
R
R
Naeyaert
J M
JM
Messiaen
L
L
Veys
E M
EM
D002648:Child; D005260:Female; D006801:Humans; D008875:Middle Aged; D012594:Scleroderma, Localized / Q000235:genetics*; D012595:Scleroderma, Systemic / Q000235:genetics*; D014430:Twins, Monozygotic / Q000235:genetics*