Gap junctions: fates worse than death?
The reasons for the molecular heterogeneity of connexin channels in vivo remain unclear. Functional replacement of one connexin gene with another has now revealed unexpected phenotypes and shows that cellular homeostasis depends not simply on cell-cell communication but also on the correct types of connexin.
White
T W
TW
Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA. twhite@hms.harvard.edu
Bruzzone
R
R
D000818:Animals; D002450:Cell Communication; D017630:Connexins / Q000235:genetics* / Q000378:metabolism; D005260:Female; D017629:Gap Junctions / Q000378:metabolism*; D008297:Male; D051379:Mice; D008822:Mice, Transgenic; D016296:Mutagenesis
D017630:Connexins