Treatment of REM sleep behavior disorder with donepezil: a report of three cases.
Three patients with REM behavior disorder whose nocturnal symptoms were markedly improved by treatment with the acetylcholinesterase inhibitor donepezil are reported. Donepezil may have a role in the treatment of REM behavior disorder, possibly through its actions on cholinergic pathways in the brainstem.
Ringman
J M
JM
Department of Neurology, University of California, Irvine Medical Center, Orange, CA, USA.
Simmons
J H
JH
D000328:Adult; D000368:Aged; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use*; D000077265:Donepezil; D006801:Humans; D007189:Indans / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010880:Piperidines / Q000627:therapeutic use*; D017286:Polysomnography; D020187:REM Sleep Behavior Disorder / Q000188:drug therapy* / Q000503:physiopathology
D002800:Cholinesterase Inhibitors; D007189:Indans; D010880:Piperidines; D000077265:Donepezil