title: Guess what! Porokeratosis of Mibelli.
abstract: A 72-year-old man had noticed, in his early forties, the appearance of well-defined papulous hyperkeratotic lesions, with increasing growth, located on both sides of his feet. After twenty-five years he consulted a dermatologist for the first time. Physical examination showed annular papules and rose-coloured plaques with atrophic centres, some of them hypopigmented, with higher and irregular borders, separated from the surrounding skin by longitudinal and well-defined furrows. The lesions presented variable sizes and shapes, some of them punctate, involving exclusively and in a bilateral form, both sides, back and sole of the feet (Figs. 1 and 2). The patient did not report any subjective symptoms. He was immunocompetent and did not remember that any relative had the same disease, nor had he been subjected to radiation treatment.
authors.affiliation: Department of Dermatology, Hospital Geral de Santo António, Rua D. Mannell 11, Edificio ex-Cicap, 4099-001, Porto, Portugal. susama@esoterica.pt
authors.forename: S
authors.initials: S
authors.lastname: Machado
authors.forename: E
authors.initials: E
authors.lastname: Silva
authors.forename: O
authors.initials: O
authors.lastname: Pereira
authors.forename: M
authors.initials: M
authors.lastname: Sanches
authors.forename: A
authors.initials: A
authors.lastname: Massa
mesh_terms: D000368:Aged; D017252:CD3 Complex / Q000032:analysis; D015704:CD4 Antigens / Q000032:analysis; D005533:Foot Dermatoses / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D017499:Porokeratosis / Q000378:metabolism / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis
chemical_list: D017252:CD3 Complex; D015704:CD4 Antigens; D009418:S100 Proteins