Effect of partial transection of spinal cord on permeability of cutaneous vessels in rats before and after treatment with neurotoxic dose of capsaicin.
Transection of the dorsal part of the spinal cord at the Th9 level disturbs permeability of blood vessels of thigh skin in rats. This effects is significantly inhibited by neurotoxic doses of capsaicin, which attests to the involvement of peptide-containing neurons. The data confirm the possibility of central modulation of the effector function of capsaicin-sensitive neurons.
Zhukova
E M
EM
Laboratory of Functional Neuromorphology, Institute of Physiology, Siberian Division of the Russian Academy of Sciences, Novosibirsk.
D000818:Animals; D002199:Capillary Permeability / Q000502:physiology; D002211:Capsaicin / Q000494:pharmacology; D008297:Male; D008833:Microcirculation / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000098:blood supply*; D013116:Spinal Cord / Q000473:pathology / Q000502:physiology*; D013119:Spinal Cord Injuries / Q000503:physiopathology
D002211:Capsaicin