Determination of four selective serotonin reuptake inhibitors by capillary isotachophoresis.
We determined an optimal electrolyte system for isotachophoresis (ITP) with conductivity detection of citalopram, fluoxetine, fluvoxamine and sertraline. The analysis conditions were applied to the determination of these selective serotonin re-uptake inhibitors in antidepressant drugs. It is shown that capillary ITP with conductivity detection is a simple and quick method for the determination of citalopram, fluoxetine, fluvoxamine and sertraline in drugs.
Buzinkaiová
T
T
Department of Analytical Chemistry, Faculty of Chemical Technology, Slovak Technical University, Bratislava. tanab@chtf.stuba.sk
Polonský
J
J
D015283:Citalopram / Q000032:analysis*; D019075:Electrophoresis, Capillary; D005473:Fluoxetine / Q000032:analysis*; D016666:Fluvoxamine / Q000032:analysis*; D017367:Selective Serotonin Reuptake Inhibitors / Q000032:analysis*; D020280:Sertraline / Q000032:analysis*
D015283:Citalopram; D005473:Fluoxetine; D016666:Fluvoxamine; D017367:Selective Serotonin Reuptake Inhibitors; D020280:Sertraline