title: Effect of nitro derivatives on electromechanical coupling in ureteral smooth muscle cells.
abstract: Double sucrose gap experiments revealed differences in the effect of nitroglycerin and sodium nitroprusside on action potential and contraction of ureteral smooth muscle cells. Unlike sodium nitroprusside, nitroglycerin inhibited voltage-dependent Ca(2+) membrane permeability. It was concluded that cGMP-independent mechanisms of the effects of nitro derivative reflect the peculiarities of excitation-contraction coupling in smooth muscles.
authors.affiliation: Department of Biophysics, Siberian Medical University, Tomsk.
authors.forename: I V
authors.initials: IV
authors.lastname: Kovalev
authors.forename: A G
authors.initials: AG
authors.lastname: Popov
authors.forename: A A
authors.initials: AA
authors.lastname: Panov
authors.forename: Y L
authors.initials: YL
authors.lastname: Borodin
authors.forename: L V
authors.initials: LV
authors.lastname: Kapilevich
authors.forename: Y D
authors.initials: YD
authors.lastname: Anfinogenova
authors.forename: M B
authors.initials: MB
authors.lastname: Baskakov
authors.forename: M A
authors.initials: MA
authors.lastname: Medvedev
mesh_terms: D000818:Animals; D005260:Female; D006168:Guinea Pigs; D009119:Muscle Contraction / Q000187:drug effects* / Q000502:physiology; D009130:Muscle, Smooth / Q000502:physiology*; D005996:Nitroglycerin / Q000494:pharmacology*; D009599:Nitroprusside / Q000494:pharmacology*; D014599:Uterus / Q000502:physiology; D014665:Vasodilator Agents / Q000494:pharmacology*
chemical_list: D014665:Vasodilator Agents; D009599:Nitroprusside; D005996:Nitroglycerin