title: Morphology discriminator feature for enhanced ventricular tachycardia discrimination in implantable cardioverter defibrillators.
abstract: The morphology discriminator (MD) feature is an electrogram template matching algorithm that intends to improve tachycardia discrimination in implantable cardioverter defibrillators (ICDs). The aim of this study was to evaluate the performance of this feature during spontaneously occurring ventricular and supraventricular tachyarrhythmias and exercise induced sinus tachycardia. Twenty-three patients (20 men, 3 women; mean age 54.3 +/- 13.8 years) with pectorally implanted Ventritex Contour MD, Angstrom MD, and Profile MD ICDs were studied. The stability of the acquired morphology template and performance of the algorithm during spontaneous tachyarrhythmias were evaluated at follow-up. A treadmill exercise test was performed in 16 patients along with continuous telemetric monitoring of matching scores. A satisfactory template could be acquired at baseline in 22 (96%) patients. Variations in electrogram morphology necessitated new template acquisition in seven (30%) patients at first follow-up (6-8 weeks postimplant). During a mean follow-up of 9.1 +/- 3.7 months, 56 ventricular tachycardia (VT) and 15 supraventricular tachycardia episodes (sinus tachycardia in two-thirds) in 11 patients were all appropriately discriminated by the MD feature. Exercise testing showed appropriate discrimination of sinus tachycardia in 15 (94%) of 16 patients. A common observation was postshock changes in electrogram morphology that resulted in transient mismatch with the template. In conclusion, the recently introduced MD feature in ICDs has a high sensitivity for detection of VT and high specificity for rejection of sinus tachycardia. Postshock changes in electrogram morphology have been observed that may cause inappropriate redetection. Marked variations of electrogram morphology over time may be a concern in some patients, especially during lead maturation.
authors.affiliation: Cardiac Arrhythmia Unit, University Hospital of Zurich, Switzerland. karduf@usz.unizh.ch
authors.forename: F
authors.initials: F
authors.lastname: Duru
authors.forename: U
authors.initials: U
authors.lastname: Bauersfeld
authors.forename: M
authors.initials: M
authors.lastname: Rahn-Schönbeck
authors.forename: R
authors.initials: R
authors.lastname: Candinas
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D017147:Defibrillators, Implantable / Q000706:statistics & numerical data; D003937:Diagnosis, Differential; D004562:Electrocardiography / Q000706:statistics & numerical data; D004566:Electrodes; D005080:Exercise Test / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013616:Tachycardia, Sinus / Q000175:diagnosis / Q000628:therapy; D017180:Tachycardia, Ventricular / Q000175:diagnosis* / Q000628:therapy*