title: Determination of the stability constants in alkanol/alpha-cyclodextrin mixed system.
abstract: The simultaneous determination of the stability constants for inclusion of alkanols with alpha-cyclodextrin (alpha-CD) was investigated in a mixed alkanol system using static head-space gas chromatography (SHSGC). The 1:1 stability constants obtained were in fair agreement with those obtained previously using other methods. The time required for determination of the stability constant was markedly reduced using this simultaneous SHSGC method.
authors.affiliation: College of Pharmacy, Nihon University, Chiba, Japan. ysaito@pha.nihon-u.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Saito
authors.forename: K
authors.initials: K
authors.lastname: Hashizaki
authors.forename: H
authors.initials: H
authors.lastname: Taguchi
authors.forename: K
authors.initials: K
authors.lastname: Tomono
authors.forename: H
authors.initials: H
authors.lastname: Goto
authors.forename: N
authors.initials: N
authors.lastname: Ogawa
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002849:Chromatography, Gas; D003505:Cyclodextrins / Q000737:chemistry / Q000493:pharmacokinetics*; D047391:alpha-Cyclodextrins
chemical_list: D003505:Cyclodextrins; D047391:alpha-Cyclodextrins; C032613:alpha-cyclodextrin