title: Diterpenoids from the roots of Croton macrostachys.
abstract: Three novel diterpenoids have been isolated from the roots of Croton macrostachys. The structure and stereochemistry of the compounds have been unambiguously settled as neoclerodan-5,10-en-19,6beta;20,12-diolide, 3alpha, 19-dihydroxytrachylobane, and 3alpha,18,19-trihydroxytrachylobane from detailed spectroscopic evidence.
authors.affiliation: Institute of Traditional Medicine, Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ditm@mamba.muchs.tz
authors.forename: M C
authors.initials: MC
authors.lastname: Kapingu
authors.forename: D
authors.initials: D
authors.lastname: Guillaume
authors.forename: Z H
authors.initials: ZH
authors.lastname: Mbwambo
authors.forename: M J
authors.initials: MJ
authors.lastname: Moshi
authors.forename: F C
authors.initials: FC
authors.lastname: Uliso
authors.forename: R L
authors.initials: RL
authors.lastname: Mahunnah
mesh_terms: D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D019665:Euphorbiaceae / Q000737:chemistry*; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D004224:Diterpenes