A case of malignant fibrous histiocytoma after breast conserving therapy for breast cancer.
A 45-year-old woman with malignant fibrous histiocytoma (MFH) of the breast following breast conserving therapy (BCT) is described. She noticed a lump in her left breast 52 months after BCT for breast cancer. The lump was excised and nodular fasciitis was initially diagnosed. However, the tumor recurred locally 4 times in the next 18 months. MFH was finally diagnosed. This case is considered to be radiation-induced sarcoma. The risk of radiation-induced sarcoma after BCT seems to be very low, however careful follow-up is necessary.
Horii
R
R
Department of Breast and Endocrine Surgery, Mitsui Memorial Hospital, Tokyo, Japan.
Fukuuchi
A
A
Nishi
T
T
Takanashi
R
R
D000328:Adult; D001859:Bone Neoplasms / Q000556:secondary / Q000601:surgery; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D015412:Mastectomy, Segmental; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects*; D012272:Ribs / Q000473:pathology