title: Eosinophilic pleural effusion due to mesalamine. Report of a rare occurrence.
abstract: Mesalamine-induced lung toxicity has often been described. We report on a case of a patient who underwent mesalamine treatment, though in the absence of established criteria required for diagnosing Crohn's disease (CD) or ulcerative colitis (UC). He developed an adverse respiratory reaction to the drug, thus definitely proving its lung damaging capacity. The clinical presentation included eosinophilic pleural effusion, a feature never previously described in association with mesalamine intake.
authors.affiliation: Clinica di Malattie dell'Apparato Respiratorio, Università di Pavia, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Trisolini
authors.forename: R
authors.initials: R
authors.lastname: Dore
authors.forename: F
authors.initials: F
authors.lastname: Biagi
authors.forename: O
authors.initials: O
authors.lastname: Luinetti
authors.forename: P
authors.initials: P
authors.lastname: Pochetti
authors.forename: N
authors.initials: N
authors.lastname: Carrabino
authors.forename: M
authors.initials: M
authors.lastname: Luisetti
mesh_terms: D000328:Adult; D004802:Eosinophilia / Q000139:chemically induced*; D005500:Follow-Up Studies; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy; D008297:Male; D019804:Mesalamine / Q000009:adverse effects* / Q000627:therapeutic use; D010996:Pleural Effusion / Q000139:chemically induced* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: D019804:Mesalamine