title: Ameliorative effects of sodium bentonite on phagocytosis and Newcastle disease antibody formation in broiler chickens during aflatoxicosis.
abstract: The ameliorative effect of graded levels of dietary sodium bentonite (0.2, 0.4 and 0.6 per cent wt/wt of feed) on in vitro-impaired phagocytosis and suppressed immune response to Newcastle disease vaccine during aflatoxicosis (AF) in broiler chicks was investigated. Both percentage and mean of phagocytic activities were decreased significantly (P < 0.05) in chicks fed 2.5 mg aflatoxin per kg feed. The addition of sodium bentonite was significantly effective in ameliorating the negative effect of AF on the percentage and mean of phagocytosis. The presence of AF alone in the diet depressed the immune response of chicks as measured by haemagglutination inhibition (HI) test. Sodium bentonite was also effective in ameliorating the suppressive effect of AF on the HI -titre in chicks vaccinated against Newcastle disease. The best results obtained when sodium bentonite was added at the rate of 0.4 per cent wt/wt of feed to the AF-containing diets.
authors.affiliation: IPA Agricultural Research Centre, P.O. Box 39094, Baghdad, Iraq.
authors.forename: I K
authors.initials: IK
authors.lastname: Ibrahim
authors.forename: A M
authors.initials: AM
authors.lastname: Shareef
authors.forename: K M
authors.initials: KM
authors.lastname: Al-Joubory
mesh_terms: D000348:Aflatoxins; D000818:Animals; D001546:Bentonite / Q000627:therapeutic use*; D002645:Chickens; D006385:Hemagglutination Inhibition Tests / Q000662:veterinary; D008297:Male; D015651:Mycotoxicosis / Q000150:complications / Q000662:veterinary*; D009521:Newcastle Disease / Q000150:complications / Q000188:drug therapy*; D010587:Phagocytosis / Q000187:drug effects*; D011201:Poultry Diseases; D014611:Vaccination / Q000662:veterinary
chemical_list: D000348:Aflatoxins; D001546:Bentonite