Isolation and characterization of adenovirus 5 from the brain of an infant with fatal cerebral edema.
This report describes a fatal case of cerebral edema caused by adenovirus in a previously healthy 18-month-old infant who developed skin rash, pulmonary congestion, and fever and who died 6 days later. Adenovirus hexon gene sequences were detected in brain tissue and brain tissue cultures. The virus was typed as adenovirus 5.
Chatterjee
N K
NK
Virus Isolation and Reference Service Laboratory, New York State Health Department, Slingerlands, NY 12159, USA.
Samsonoff
W A
WA
Balasubramaniam
N
N
Rush-Wilson
K
K
Spargo
W
W
Church
T M
TM
D000258:Adenovirus Infections, Human / Q000150:complications / Q000821:virology*; D000260:Adenoviruses, Human / Q000235:genetics / Q000302:isolation & purification* / Q000648:ultrastructure; D001483:Base Sequence; D001921:Brain / Q000648:ultrastructure / Q000821:virology*; D001929:Brain Edema / Q000150:complications / Q000473:pathology*; D004279:DNA, Viral / Q000235:genetics; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012689:Sequence Homology, Nucleic Acid; D014407:Tumor Cells, Cultured
D004279:DNA, Viral