title: Eyelid abnormalities in lamellar ichthyoses.
abstract: OBJECTIVE
  To describe eyelid abnormalities in lamellar ichthyoses (LI).
  
  
  METHODS
  Retrospective observational case series.
  
  
  METHODS
  Eight patients with classic LI and two patients with congenital ichthyosiform erythroderma.
  
  
  METHODS
  Results of eyelid and corneal examinations of 10 patients with LI were reviewed and analyzed with emphasis on the relationship between eyelid ectropion and corneal damage.
  
  
  RESULTS
  All patients presented with cicatricial lagophthalmos. Of the eight patients with classic LI, five had ectropion of the four eyelids, one had only lower ectropion, and two had no degree of ectropion. Two patients with congenital ichthyosiform erythroderma had distinct eyelid abnormalities, including madarosis and eyelash retraction. Loss of vision caused by corneal damage was found in three patients with classic LI. Of these three patients, two did not have upper eyelid ectropion.
  
  
  CONCLUSIONS
  Severe corneal damage can occur in LI even if there is no upper or lower eyelid ectropion.
authors.affiliation: Department of Ophthalmology of School of Medicine of Ribeirão Preto, São Paulo, Brazil.
authors.forename: A A
authors.initials: AA
authors.lastname: Cruz
authors.forename: F A
authors.initials: FA
authors.lastname: Menezes
authors.forename: R
authors.initials: R
authors.lastname: Chaves
authors.forename: R
authors.initials: R
authors.lastname: Pinto Coelho
authors.forename: E F
authors.initials: EF
authors.lastname: Velasco
authors.forename: H
authors.initials: H
authors.lastname: Kikuta
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003316:Corneal Diseases / Q000209:etiology / Q000473:pathology; D004483:Ectropion / Q000209:etiology* / Q000473:pathology; D005124:Eye Abnormalities / Q000209:etiology* / Q000473:pathology; D005143:Eyelids / Q000002:abnormalities* / Q000473:pathology; D005260:Female; D006801:Humans; D016113:Ichthyosiform Erythroderma, Congenital / Q000150:complications; D017490:Ichthyosis, Lamellar / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies