[Localized bullous pemphigoid induced by thermal burn].
BACKGROUND
Induced bullous pemphigoid is known to be triggered by drugs and some physical agents. Six cases of bullous pemphigoid induced by thermal burns have been reported since 1991.


METHODS
We observed a bullous eruption around thermal burns of the left leg in a 89 year-old woman. Bullous pemphigoid was diagnosed by histological and immunohistochemical findings with a sub-epidermal blister and linear IgG and C3 deposition at the dermal-epidermal junction. Indirect immunofluorescence was negative. The eruption rapidly resolved with topical steroids.


CONCLUSIONS
We describe a bullous pemphigoid induced by a thermal burn. This case is original because the eruption was localized only around the site of the burn and healed with topical steroids. In the literature, there are 6 other cases reported but only one localized. We discuss the hypothesis of asymptomatic bullous pemphigoid exacerbated by presentation of bullous pemphigoid antigen by thermal burns or self immunization against antigens altered by burns.
Vermeulen
C
C
Service de Dermatologie, Fondation-Hôpital Saint-Joseph, 185, rue Raymond-Losserand, 75014 Paris.
Janier
M
M
Panse
I
I
Daniel
F
F
D000368:Aged; D000369:Aged, 80 and over; D002056:Burns / Q000150:complications* / Q000473:pathology; D003176:Complement C3 / Q000032:analysis; D005260:Female; D019085:Fluorescent Antibody Technique, Direct; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007869:Leg Injuries / Q000150:complications* / Q000473:pathology; D010391:Pemphigoid, Bullous / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D012867:Skin / Q000473:pathology
D003176:Complement C3; D007074:Immunoglobulin G