title: Mucosal antioxidant defense is not impaired in ulcerative colitis.
abstract: OBJECTIVE
  In this study, mucosal antioxidant defense was investigated in the biopsy samples from 12 patients with active ulcerative colitis and from 13 patients under remission.
  
  
  METHODS
  Biopsy samples obtained from healthy colon parts of the same subjects were used as control.
  
  
  RESULTS
  No changes were observed between superoxide dismutase, glutathione peroxidase and catalase enzyme activities of control or inflamed biopsy samples. However, antioxidant potential values were found to be higher and malondialdehyde levels lower in inflamed samples compared with controls.
  
  
  CONCLUSIONS
  Our results show that in contrast to previous suggestions, mucosal antioxidant defense is not impaired in ulcerative colitis.
authors.affiliation: Ankara University Medical Faculty, Department of Biochemistry, Turkey.
authors.forename: I
authors.initials: I
authors.lastname: Durak
authors.forename: M H
authors.initials: MH
authors.lastname: Yasa
authors.forename: A
authors.initials: A
authors.lastname: Bektas
authors.forename: M
authors.initials: M
authors.lastname: Kaçmaz
authors.forename: M Y
authors.initials: MY
authors.lastname: Cimen
authors.forename: H S
authors.initials: HS
authors.lastname: Oztürk
mesh_terms: D000975:Antioxidants / Q000378:metabolism*; D001706:Biopsy; D002374:Catalase / Q000378:metabolism; D003093:Colitis, Ulcerative / Q000201:enzymology / Q000276:immunology*; D005979:Glutathione Peroxidase / Q000378:metabolism; D006801:Humans; D018928:Immunity, Mucosal; D008315:Malondialdehyde / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D000975:Antioxidants; D008315:Malondialdehyde; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase