Polyradiculoneuritis after botulinum toxin therapy for cervical dystonia.
A 40-year-old man with cervical dystonia developed an acute inflammatory demyelinating polyradiculoneuritis after botulinum toxin type A treatment. Some cases of idiopathic brachial plexopathy and polyradiculoneuritis have been reported to date. Although a causal relationship is not firmly established, the clinical temporal profile suggests a pathogenic relationship. In patients with cervical dystonia, further use of type A botulinum toxin should be considered contraindicated, and the use of another type of botulinum toxin should be taken into consideration.
Burguera
J A
JA
Department of Neurology, Hospital Universitari La Fe, Valencia, Spain.
Villaroya
T
T
López-Alemany
M
M
D000328:Adult; D019274:Botulinum Toxins, Type A / Q000009:adverse effects* / Q000627:therapeutic use; D003711:Demyelinating Diseases / Q000139:chemically induced; D004421:Dystonia / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D009465:Neuromuscular Agents / Q000009:adverse effects* / Q000627:therapeutic use; D011129:Polyradiculoneuropathy / Q000139:chemically induced*
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A