Retention of spatial information in hippocampally damaged rats overtrained on a cartographic task.
Hippocampal rats were overtrained on a cartographic task until they reached a performance equal to that of the control group. Twenty-four days later, during a retraining period, lesioned rats showed a profound retention deficit as compared to controls. However, Expt. 2 shows no retention deficit when a guidance strategy is used to acquire the spatial task. These results suggest that the hippocampus is crucial for long-term retention/consolidation of allocentric spatial information.
Ramos
J M
JM
Departamento de Psicología Experimental y Fisiología del Comportamiento, Facultad de Psicología, Universidad de Granada, 18071, Granada, Spain. mmjramos@platon.ugr.es
D000818:Animals; D001925:Brain Damage, Chronic / Q000503:physiopathology* / Q000523:psychology; D007839:Functional Laterality; D006624:Hippocampus / Q000473:pathology / Q000502:physiology / Q000503:physiopathology*; D008297:Male; D018782:Maze Learning / Q000502:physiology*; D008568:Memory / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D012016:Reference Values; D013028:Space Perception