title: [Gradually enhancing breast cancer on dynamic MRI].
abstract: OBJECTIVE
  The aim of our study was to evaluate the frequency and the radiologic and pathologic features of gradually enhancing breast cancers on contrast enhanced dynamic MRI.
  
  
  METHODS
  83 patients with pathologically proven breast cancer underwent contrast enhanced dynamic MRI. Breast cancers that showed a gradually enhancing pattern were selected, and their pathological features and the findings in other imaging modalities were retrospectively analyzed.
  
  
  RESULTS
  Of 83 lesions, 8 lesions (10%) showed a gradually enhancing pattern on dynamic MRI. The lesions included 3 papillotubular carcinomas, 3 scirrhous carcinomas, one solid-tubular carcinoma, and one mucinous carcinoma. All of them had imaging features suggesting malignancy on mammography and ultrasonography. Histopathologically, all 7 invasive ductal carcinomas showed prominent fibrosis in the stroma, and one showed many dilated ducts. One mucinous carcinoma showed large mucinous pools.
  
  
  CONCLUSIONS
  Some breast cancers may show a gradually enhancing pattern on dynamic MRI. Other imaging features should be taken into account in the differential diagnosis of breast tumors.
authors.affiliation: Department of Radiology, Nagasaki University School of Medicine.
authors.forename: I
authors.initials: I
authors.lastname: Isomoto
authors.forename: T
authors.initials: T
authors.lastname: Koshiishi
authors.forename: T
authors.initials: T
authors.lastname: Okimoto
authors.forename: H
authors.initials: H
authors.lastname: Okada
authors.forename: M
authors.initials: M
authors.lastname: Uetani
authors.forename: K
authors.initials: K
authors.lastname: Hayashi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged