title: [Gastroesophageal reflux and respiratory diseases].
abstract: There is a relationship between gastroesophageal reflux and respiratory diseases. Reflux may trigger and aggravate respiratory diseases especially bronchial asthma. Both clinical and experimental observations suggest that the pathogenic mechanisms may be a vagal reflex and/or microaspiration of gastric acid into the trachea. General measures to avoid reflux and proton pomp inhibitor together with inhaled corticosteroid are the choice for treatment of asthma associated with gastroesophageal reflux. Xanthine derivatives and beta 2 adrenergic agonist might be withheld in these patients. A laparoscopic surgical treatment may be an option for patients with persistent symptoms.
authors.affiliation: Saitama Caldiovasculer and Respiratory Center.
authors.forename: K
authors.initials: K
authors.lastname: Futsuhara
authors.forename: M
authors.initials: M
authors.lastname: Kanazawa
mesh_terms: D001249:Asthma / Q000209:etiology; D005764:Gastroesophageal Reflux / Q000150:complications*; D006801:Humans; D012140:Respiratory Tract Diseases / Q000209:etiology*