Safety of femoral closure devices after percutaneous coronary interventions in the era of glycoprotein IIb/IIIa platelet blockade.
We compared in-hospital femoral complications of Angio-Seal, Perclose, and manual compression in consecutive patients who underwent percutaneous coronary interventions in the era of glycoprotein IIb/IIIa platelet inhibition. Femoral closure devices have a similar overall risk profile as manual compression, even in patients treated with glycoprotein IIb/IIIa platelet inhibition, although certain rare complications such as retroperitoneal hemorrhage and severe access-site infection may be more common with the use of these devices.
Cura
F A
FA
Department of Cardiology, Cleveland Clinic Foundation, Ohio, USA.
Kapadia
S R
SR
L'Allier
P L
PL
Schneider
J P
JP
Kreindel
M S
MS
Silver
M J
MJ
Yadav
J S
JS
Simpfendorfer
C C
CC
Raymond
R R
RR
Tuzcu
E M
EM
Franco
I
I
Whitlow
P L
PL
Topol
E J
EJ
Ellis
S G
SG
D015906:Angioplasty, Balloon, Coronary; D005260:Female; D005263:Femoral Artery / Q000293:injuries; D006489:Hemostatic Techniques / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors*; D011312:Pressure / Q000009:adverse effects; D011446:Prospective Studies; D012044:Regression Analysis; D012449:Safety; D013536:Suture Techniques / Q000009:adverse effects; D014652:Vascular Diseases / Q000209:etiology*
D019039:Platelet Glycoprotein GPIIb-IIIa Complex