title: Phytochemical and pharmacological studies on Monechma ciliatum.
abstract: The leaves of Monechma ciliatum were found to contain alkaloids, glycosides, proteins, tannins and saponins. The hot methanol extract (HME) of the leaves, previously found to have potent oxytocic effect in various species was fractionated in various solvents and the fractions analysed chemically and also assayed on the rat uterus in an attempt to identify the chemical constituents present and in particular the oxytocic principle. Positive reaction with ninhydrin spray suggests that the oxytocic constituent is an amino acidic derivative.
authors.affiliation: Department of Pharmacology and Clinical Pharmacy, University of Jos, Jos, Nigeria.
authors.forename: M O
authors.initials: MO
authors.lastname: Uguru
authors.forename: F
authors.initials: F
authors.lastname: Evans
mesh_terms: D000818:Animals; D005260:Female; D010120:Oxytocics / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry*; D051381:Rats; D014599:Uterus / Q000187:drug effects
chemical_list: D010120:Oxytocics; D010936:Plant Extracts