[Heart failure: the electrophysiological connection. Myocardial stunning and heart failure: mechanisms in common?].
The delayed recovery of function after brief episodes of ischemia is known as stunning. Myocardial stunning and heart failure would, at first glance, appear to have little in common other than the obvious contractile dysfunction in both settings. Here I describe studies which shed new light on the underlying mechanisms of these two forms of contractile dysfunction, revealing unexpected fundamental similarities.
Marbán
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Profesor de Medicina y Fisiología, The Johns Hopkins University, Baltimore, MD 21205, USA. marban@jhmi.edu
D004594:Electrophysiology; D006333:Heart Failure / Q000503:physiopathology*; D006801:Humans; D017202:Myocardial Ischemia / Q000503:physiopathology; D017682:Myocardial Stunning / Q000503:physiopathology*