title: [A case of primitive meningeal rhabdomyosarcoma. Histological, immunohistochemical and ultrastructural study].
abstract: A 64 year-old patient, complained of headache and neurological disorders. CT scan found a voluminous solitary tumor of the posterior part of the left cavernous sinus. Removal of tumor was followed by a rapid recurrence and by the patient's death. Histologic study found a malignant undifferentiated tumoral proliferation, with strap-like cells. Immunohistochemical stains were positive for conjunctival and muscular differentiation. Ultrastructural study revealed intracytoplasmic filamentous striated structure. The primary meningeal rhabdomyosarcoma is an exceptional tumor, generally affecting young patients. Its prognosis is poor and its histogenesis remains unclear.
authors.affiliation: Laboratoire d'Anatomie Pathologique, Hôpital Charles-Nicolle, CHU de Rouen.
authors.forename: F
authors.initials: F
authors.lastname: Le Pessot
authors.forename: A
authors.initials: A
authors.lastname: François
authors.forename: F
authors.initials: F
authors.lastname: Proust
authors.forename: P
authors.initials: P
authors.lastname: Freger
authors.forename: A
authors.initials: A
authors.lastname: Laquerrière
mesh_terms: D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy / Q000648:ultrastructure; D008875:Middle Aged; D012208:Rhabdomyosarcoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy / Q000648:ultrastructure; D014057:Tomography, X-Ray Computed