title: Zinc fingers: DNA binding and protein-protein interactions.
abstract: The zinc finger domain is a very ubiquitous structural element whose hallmark is the coordination of a zinc atom by several amino acid residues (cysteines and histidines, and occasionally aspartate and glutamate). These structural elements are associated with protein-nucleic acid recognition as well as protein-protein interactions. The purpose of this review is to examine recent data on the DNA and protein binding properties of a few zinc fingers whose three dimensional structure is known.
authors.affiliation: Instituto de Bioquímica, Universidad Austral de Chile, Valdivia, Chile. oleon@uach.cl
authors.forename: O
authors.initials: O
authors.lastname: Leon
authors.forename: M
authors.initials: M
authors.lastname: Roth
mesh_terms: D000818:Animals; D004268:DNA-Binding Proteins / Q000502:physiology*; D006801:Humans; D016335:Zinc Fingers / Q000502:physiology*
chemical_list: D004268:DNA-Binding Proteins