title: Prolonged cerebral salt wasting syndrome associated with the intraventricular dissemination of brain tumors. Report of two cases and review of the literature.
abstract: Hyponatremia is a frequent event in neurosurgery practice and is usually associated with subarachnoid hemorrhage, head trauma, infections and neoplasms. The two common clinical manifestations are the inappropriate secretion of antidiuretic hormone (SIADH) and the cerebral salt wasting syndrome (CSWS), which were usually attributed to each other due to identical clinical presentation. In contrast to the better-recognized SIADH, there has not been a uniform consensus over the humoral and neural mechanisms of CSWS and functional aspects of renal response. In this article, we report on 2 cases of a primitive neuroectodermal tumor with prolonged CSWS manifested during the intraventricular dissemination of primary disease and the high catabolic stage.
authors.affiliation: Department of Neurosurgery, Hacettepe University School of Medicine, Ankara, Turkey. oruckaptan@yahoo.com
authors.forename: H H
authors.initials: HH
authors.lastname: Oruckaptan
authors.forename: P
authors.initials: P
authors.lastname: Ozisik
authors.forename: N
authors.initials: N
authors.lastname: Akalan
mesh_terms: D001928:Brain Diseases, Metabolic / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism*; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis*; D002675:Child, Preschool; D018450:Disease Progression; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000175:diagnosis; D007010:Hyponatremia / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism; D007177:Inappropriate ADH Syndrome / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism*; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009361:Neoplasm Invasiveness; D018242:Neuroectodermal Tumors, Primitive / Q000150:complications / Q000175:diagnosis*; D012965:Sodium Chloride / Q000378:metabolism* / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D012965:Sodium Chloride