[The evaluation of the role of recovery from potentially lethal and sublethal damages in the RBE of densely ionizing radiation].
The new data confirming the relations between RBE and recovery of cells are presented. The quantitative evaluation of the contribution of potentially lethal and sublethal damage recovery in radiosensitivity of cells of various origin after exposure to low- and high-LET ionizing radiation was carried out. The conclusion about the greater contribution of potentially lethal damage recovery in the magnitude of RBE in comparison with sublethal damage recovery was made.
Shvedenko
V I
VI
Medical Radiological Research Center, Russian Academy of Medical Sciences, Obninsk, Russia. mrrc@obninsk.ru
Petin
V G
VG
D000512:Alpha Particles; D000818:Animals; D004171:Diploidy; D004926:Escherichia coli / Q000528:radiation effects; D005720:Gamma Rays; D006238:Haploidy; D018499:Linear Energy Transfer / Q000528:radiation effects; D008223:Lymphoma; D051379:Mice; D009154:Mutation / Q000528:radiation effects; D011836:Radiation Tolerance; D012062:Relative Biological Effectiveness; D012441:Saccharomyces cerevisiae / Q000528:radiation effects; D014407:Tumor Cells, Cultured