title: Spatial resolution of epicardial pace mapping using body surface potentials.
abstract: Body surface potential maps (BSPMs) recorded during pace mapping provide an important non-invasive means for identifying local cardiac events; recent clinical studies demonstrated that endocardial pacing sites can be resolved within less than 10 mm. We sought to determine whether similar spatial resolution could be achieved during epicardial pacing. Four patients who were undergoing either heart valve replacement (one), aortocoronary bypass graft (one), or both (two) were studied. In each patient, a pair of epicardial electrodes was placed intraoperatively at the middle aspect of the right ventricular free wall. The distance between the neighbouring electrodes was 10 mm. Five days after the surgery, ECGs were acquired from 35 leads during pacing from each epicardial electrode. We determined the distributions of QRS integrals (the net area under the ECG signal) and compared integrals corresponding to pacing from each of the adjacent electrodes using statistical indices. Student's t-test was applied to these indices and in all the patients revealed that differences in distributions of QRS integral maps were statistically significant (p < 0.01). Results of our study indicate that the non-invasive acquisition of body surface ECGs could resolve epicardial breakthrough sites within 10 mm, which may be useful in facilitating therapeutic ablations in patients with ventricular tachycardias.
authors.affiliation: Department of Cardiovascular Surgery, Medical Center Ljubljana, Slovenia. samarinsilvia@hotmail.com
authors.forename: S
authors.initials: S
authors.lastname: Samarin
authors.forename: R
authors.initials: R
authors.lastname: Hren
authors.forename: R
authors.initials: R
authors.lastname: Trobec
authors.forename: V
authors.initials: V
authors.lastname: Avbelj
authors.forename: B
authors.initials: B
authors.lastname: Gersak
mesh_terms: D000368:Aged; D018780:Body Surface Potential Mapping; D002304:Cardiac Pacing, Artificial; D004562:Electrocardiography; D006801:Humans; D008875:Middle Aged; D010496:Pericardium / Q000503:physiopathology*