title: Outbreak of tuberculosis associated with a church.
abstract: Investigation of an outbreak of tuberculosis (TB) in a West Midlands health district in 1999 revealed spread in an extended family network and to church contacts. Within the family four cases of smear positive TB, four cases of smear negative infection, and 14 cases requiring chemoprophylaxis were identified. One of the infectious cases visited a local church on two occasions, which resulted in a further 16 cases of infection including one case of tuberculous meningitis. DNA fingerprinting of isolates from five culture positive cases indicated that the same strain of Mycobacterium tuberculosis was responsible. This outbreak is a reminder that while outbreaks of TB usually arise within households or family networks, where close contact over extended periods provides more opportunity for exposure, community outbreaks of TB can occur after only causal contact.
authors.affiliation: Birmingham Public Health Laboratory.
authors.forename: S A
authors.initials: SA
authors.lastname: Cook
authors.forename: I
authors.initials: I
authors.lastname: Blair
authors.forename: M
authors.initials: M
authors.lastname: Tyers
mesh_terms: D000328:Adult; D019072:Antibiotic Prophylaxis; D002648:Child; D002835:Christianity; D016358:Contact Tracing; D004196:Disease Outbreaks / Q000517:prevention & control*; D004352:Drug Resistance, Microbial; D004739:England / Q000453:epidemiology; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*