title: Scleral outfolding for macular translocation.
abstract: OBJECTIVE
  To report experimental study and clinical observation of scleral outfolding for macular translocation.
  
  
  METHODS
  In six human cadaver eyes, circumferential mattress sutures to create sclera infoldings were compared with radial-interrupted mattress sutures to create scleral outfoldings. In a 75-year-old man with macular degeneration and choroidal neovascular membrane, radial-interrupted mattress sutures were used for macular translocation.
  
  
  RESULTS
  In the human cadaver eyes, circumferential mattress sutures for scleral infolding created an average decrease in corresponding internal anteroposterior retinal contour of 0.36 mm. Radial-interrupted mattress sutures for scleral outfoldings created an average decrease in the corresponding internal anteroposterior retinal contour of 4. 61 mm. The statistical significance of the difference between infoldings of the sclera versus outfoldings of the sclera had a P value of.0001.
  
  
  CONCLUSIONS
  Initial experimental and clinical study suggests that radial-interrupted mattress sutures may generate more shortening of the internal scleral surface and greater macular translocation than circumferential mattress sutures. Additional studies are needed to evaluate the long-term effects of radial-interrupted mattress sutures and macular translocation for treatment of subfoveal choroidal neovascularization secondary to age-related macular degeneration.
authors.affiliation: Glaser Murphy Retina Treatment Center, Chevy Chase, Maryland 20815, USA.
authors.forename: S B
authors.initials: SB
authors.lastname: Lin
authors.forename: B M
authors.initials: BM
authors.lastname: Glaser
authors.forename: D
authors.initials: D
authors.lastname: Gould
authors.forename: T A
authors.initials: TA
authors.lastname: Baudo
authors.forename: R R
authors.initials: RR
authors.lastname: Lakhanpal
authors.forename: R P
authors.initials: RP
authors.lastname: Murphy
mesh_terms: D000368:Aged; D020256:Choroidal Neovascularization / Q000209:etiology / Q000601:surgery*; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008266:Macula Lutea / Q000637:transplantation*; D008268:Macular Degeneration / Q000150:complications / Q000601:surgery*; D008297:Male; D012590:Sclera / Q000601:surgery*; D013536:Suture Techniques; D016896:Treatment Outcome; D014792:Visual Acuity; D014821:Vitrectomy