title: Total synthesis of (+)-crocacin C.
abstract: The first asymmetric synthesis of (+)-crocacin C (3) is described which served to confirm the absolute configuration of this compound. The key step in the sequence was the stereoselective assembly of the (E,E)-diene amide side chain by a Stille cross-coupling between the stannane 5 and vinyl iodide 6.
authors.affiliation: School of Chemistry, The University of Melbourne, Victoria 3010, Australia.
authors.forename: J T
authors.initials: JT
authors.lastname: Feutrill
authors.forename: M J
authors.initials: MJ
authors.lastname: Lilly
authors.forename: M A
authors.initials: MA
authors.lastname: Rizzacasa
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry; D011090:Polyenes / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000935:Antifungal Agents; D011090:Polyenes; C089608:crocacin