Recurrence of rapidly progressive glomerulonephritis probably associated with two different kinds of drugs.
We describe a rare case that developed a rapidly progressive glomerulonephritis twice in a 69-year-old man during a course of treatment, first with allopurinol and then with piperacillin. The cessation of each treatment was followed by spontaneous recovery in renal function. A renal biopsy showed crescentic glomerulonephritis with mild tubulointerstitial change and a skin biopsy showed leukocytoclastic vasculitis. This is, to our knowledge, a very rare case of crescentic glomerulonephritis, probably associated with vasculitis during a course of treatment with two different kinds of drugs.
Aoki
S
S
Department of Internal Medicine, Saga Medical School, Japan.
Kotooka
N
N
Yokoyama
M
M
Ikeda
Y
Y
Tomiyoshi
Y
Y
Sakemi
T
T
Yonemitsu
N
N
D000368:Aged; D000493:Allopurinol / Q000009:adverse effects*; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D018450:Disease Progression; D005921:Glomerulonephritis / Q000139:chemically induced*; D006801:Humans; D008297:Male; D012008:Recurrence; D013997:Time Factors
D000900:Anti-Bacterial Agents; D000493:Allopurinol