Endocrine correlates of male breast cancer risk: a case-control study in Athens, Greece.
We studied the relation of certain endocrine-related variables among 23 cases of male breast cancer and 76 apparently healthy male controls. There were significant inverse associations with smoking (P = 0.03), birth order (P = 0.02) and reported frequency of orgasms in later life (P = 0.0004). The study provides strong indirect evidence that endocrine factors are important in the aetiology of male breast cancer.
Petridou
E
E
Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
Giokas
G
G
Kuper
H
H
Mucci
L A
LA
Trichopoulos
D
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D000428:Alcohol Drinking; D018567:Breast Neoplasms, Male / Q000209:etiology*; D016022:Case-Control Studies; D006115:Greece; D006728:Hormones / Q000502:physiology*; D006801:Humans; D008297:Male; D017533:Marital Status; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors; D012725:Sexual Behavior; D012907:Smoking
D006728:Hormones