Vancomycin-intermediate Staphylococcus aureus in Korea.
Recent reports on some methicillin-resistant Staphylococcus aureus (MRSA) with reduced susceptibility to vancomycin have been a major concern in Korea because of the widespread use of vancomycin due to a high prevalence of MRSA in the country. We describe a 45-year-old man with long-standing pelvic abscess due to MRSA. In spite of vancomycin and teicoplanin treatment for a long period of time, the patient died from MRSA sepsis. The blood culture isolate of MRSA exhibited reduced susceptibility to vancomycin (MIC, 8 microg/ml). This is the first report of a vancomycin-intermediate S. aureus case from Korea.
Kim
M N
MN
Department of Clinical Pathology, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea. mnkim@www.amc.seoul.kr
Pai
C H
CH
Woo
J H
JH
Ryu
J S
JS
Hiramatsu
K
K
D018784:Abdominal Abscess / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D017809:Fatal Outcome; D006801:Humans; D007723:Korea; D008297:Male; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification*; D017334:Teicoplanin / Q000627:therapeutic use*; D014640:Vancomycin / Q000494:pharmacology* / Q000627:therapeutic use*
D017334:Teicoplanin; D014640:Vancomycin