title: Clinics in diagnostic imaging (51). Multiloculated cerebral abscesses due to paradoxical cardiac emboli.
abstract: A 19-year-old woman with congenital cyanotic heart disease (Epstein anomaly and ventricular septal defect) had persistent headaches and intermittent fever for five weeks. Physical examination revealed central cyanosis, finger clubbing and fever. The leucocyte count was elevated. Cerebral MR imaging showed the characteristic features of brain abscesses in the right frontal lobe, including multiloculation with adjacent satellite lesions, ring enhancement, T1-hyperintense and T2-hypointense signal areas within the abscess rim, as well as hypointense internal concentric rings on T2-weighted images. The diagnosis of brain abscesses was confirmed by craniotomy and pus drainage. She made a good recovery with a combination of antibiotics and surgery. Follow-up CT scans showed only changes of encephalomalacia at the healed abscess site. The aetiology, clinical features, and the role of CT and MR imaging in the diagnosis and management of brain abscess are discussed.
authors.affiliation: Department of Diagnostic Radiology, Kwong Wah Hospital, Hong Kong.
authors.forename: J F
authors.initials: JF
authors.lastname: Liu
authors.forename: H S
authors.initials: HS
authors.lastname: Lam
authors.forename: J R
authors.initials: JR
authors.lastname: Jinkins
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents; D001922:Brain Abscess / Q000175:diagnosis* / Q000209:etiology; D001929:Brain Edema / Q000209:etiology; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004437:Ebstein Anomaly / Q000150:complications*; D019320:Embolism, Paradoxical / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D006345:Heart Septal Defects, Ventricular / Q000150:complications*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents