title: Prophylactic and therapeutic application of antimicrobial agents in the oral cavity.
abstract: Antimicrobial substances are used for many prophylactic and therapeutic reasons in the oral cavity. They are used as mouthrinses, for the irrigation of specific oral locations, in form of gels, or varnishes. Different antimicrobial agents are available and some preparations are complex compositions of these compounds. Although it has been proven that several agents are suited to achieve a considerable reduction of oral microorganisms many questions concerning the clinical benefit are yet to be answered. This report summarises the evidence of the efficacy of oral antiseptics (especially chlorhexidine, pvp-iodine, and Listerine) depending on different indications, which is the basis for clinical and practical recommendations.
authors.affiliation: Institute of Hygiene and Environmental Medicine, University of Greifswald, Germany. pitten@uni-greifswald.de
authors.forename: F A
authors.initials: FA
authors.lastname: Pitten
authors.forename: C
authors.initials: C
authors.lastname: Splieth
authors.forename: A
authors.initials: A
authors.lastname: Kramer
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D016470:Bacteremia / Q000517:prevention & control; D006801:Humans; D009059:Mouth Diseases / Q000382:microbiology* / Q000517:prevention & control*; D009067:Mouthwashes
chemical_list: D000890:Anti-Infective Agents; D009067:Mouthwashes