Regioselective synthesis of medium-sized bicyclic butenolides by lewis acid catalyzed cyclization of cyclic 1, 3-Bis(trimethylsilyloxy)-1,3-butadienes with oxalyl chloride
A new strategy for the synthesis of medium-sized bicyclic gamma-alkylidenebutenolides is reported which involves Me(3)SiOTf-catalyzed cyclization of cyclic 1, 3-bis(trimethylsilyloxy)-1,3-butadienes with oxalyl chloride.
Langer
P
Institut fur Organische Chemie der Georg-August-Universitat Gottingen, Tammannstrasse 2, 37077 Gottingen, Germany.
Saleh
NN