title: Hypercalcemia and T-cell lymphoma with acquired immunodeficiency syndrome: occurrence without human T-cell leukemia virus-I.
abstract: We describe the case of a patient with acquired immunodeficiency syndrome (AIDS) who had a CD4 cell count of 60/microL, bilateral hilar adenopathy, and hypercalcemia. Transbronchial biopsy showed T-cell anaplastic large cell lymphoma. Serology was negative for human T-cell leukemia virus-I (HTLV-I). This appears to be the first case of T-cell anaplastic large cell lymphoma occurring in an AIDS patient with hypercalcemia who was seronegative for HTLV-I.
authors.affiliation: Department of Medicine, Memorial Hospital of Rhode Island, Pawtucket, USA.
authors.forename: S
authors.initials: S
authors.lastname: Kottilil
authors.forename: R
authors.initials: R
authors.lastname: Fram
authors.forename: K
authors.initials: K
authors.lastname: Cortez
authors.forename: S
authors.initials: S
authors.lastname: Schwartz
authors.forename: S H
authors.initials: SH
authors.lastname: Kesan
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis*; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D019046:Bone Marrow Neoplasms / Q000175:diagnosis; D001932:Brain Neoplasms / Q000175:diagnosis; D018791:CD4 Lymphocyte Count; D017809:Fatal Outcome; D006679:HIV Seropositivity / Q000175:diagnosis; D015497:HIV-1; D015368:Human T-lymphotropic virus 1; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis*; D008175:Lung Neoplasms / Q000175:diagnosis*; D016483:Lymphoma, AIDS-Related / Q000175:diagnosis*; D017728:Lymphoma, Large-Cell, Anaplastic / Q000175:diagnosis; D016399:Lymphoma, T-Cell / Q000175:diagnosis*; D008297:Male; D019562:Viral Load