[Ecology and social organization of African tropical forest primates: aid in understanding retrovirus transmission].
The risk of transmission of primate viruses to humans is great because of their genetic proximity. It is now clear that the HIV group of retroviruses came from primates and that the origin of HIV1 is the chimpanzee subspecies of Central Africa, Pan troglodytes troglodytes. Many African primates are natural hosts of retroviruses and details of the natural history of both hosts and viruses are essential to understand the evolution of the latter. Data on the demography, ecology and behaviour of three species of primates (gorillas, chimpanzees and mandrills), studied in the Lopé Reserve in Central Gabon since 1983, are analysed to identify the factors that allow, or favour, disease transmission within each species, between different species and between primates and humans. The comparison of the relative degree of risk suggests that of the three species, chimpanzees are the most susceptible to exposure to infection both from conspecifics and from other species. With respect to humans, the comparative analysis suggests greater exposure to viruses of mandrills and gorillas than to those of chimpanzees. For primates, major risk factors are: large social groups; bites inflicted in fights; social grooming; and predation on mammals. However, given that contacts between social groups of the same species are rare, the spread of a virus through a population will be slow and uncertain. Hunting wild animals is the behaviour most likely to provide transmission routes for primate viruses into human populations because of the high probability of blood-blood contact. Not only the hunters themselves, but also women who prepare bush meat for cooking and people involved in trade of carcasses are at high risk of transmission of pathogens. Hunting of bush meat is increasing in Central Africa due to the economic recession and the spread of logging into the forests of the interior of the region. To counter the significant risk of transmission of known, as well as new, diseases from primates to humans, urgent measures are needed to attack the root causes of commercial hunting which is not only risk to public health but also a serious threat to biodiversity in the region.
Tutin
C E
CE
Centre international de recherches médicales, Franceville, Gabon.
D000818:Animals; D001733:Bites and Stings; D004198:Disease Susceptibility; D004463:Ecology; D005260:Female; D005681:Gabon; D006071:Gorilla gorilla / Q000502:physiology / Q000821:virology; D006120:Grooming; D006801:Humans; D008297:Male; D002679:Pan troglodytes / Q000502:physiology / Q000821:virology; D010215:Papio / Q000502:physiology / Q000821:virology; D011323:Primates / Q000502:physiology* / Q000821:virology*; D012192:Retroviridae Infections / Q000635:transmission / Q000662:veterinary*; D012307:Risk Factors; D012919:Social Behavior; D013045:Species Specificity; D014197:Trees; D014329:Tropical Climate