title: Cardiac involvement in total generalized lipodystrophy (Berardinelli- Seip syndrome).
abstract: Total generalized lipodystrophy (Berardinelli - Seip Syndrome) is a rare hereditary disease characterized by insulin-resistant diabetes mellitus and a small quantity of adipose tissue and is of unknown origin. Common cardiovascular alterations related to this syndrome are cardiac hypertrophy and arterial hypertension. This article reports a case of Berardinelli - Seip syndrome and reviews the literature with special emphasis on the cardiovascular manifestations of this syndrome.
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
authors.forename: R F
authors.initials: RF
authors.lastname: Viégas
authors.forename: R V
authors.initials: RV
authors.lastname: Diniz
authors.forename: T M
authors.initials: TM
authors.lastname: Viégas
authors.forename: E B
authors.initials: EB
authors.lastname: Lira
authors.forename: D R
authors.initials: DR
authors.lastname: Almeida
mesh_terms: D006332:Cardiomegaly / Q000150:complications* / Q000000981:diagnostic imaging; D003923:Diabetes Mellitus, Lipoatrophic / Q000150:complications*; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D011859:Radiography; D014463:Ultrasonography