title: Analysis and modulation of spike trains and oscillations in identified neural network of Lymnaea stagnalis L.
abstract: Identified neurons and members of functionally characterized clusters of the central nervous system of Lymnaea stagnalis L. were studied. Long-term spike trains (10-100 min) were collected using current clamp method. Firing patterns were analyzed by several mathematical tools e.g.: spike density function (SDF), interspike interval (ISI), Fourier-transform. Both the spike trains and oscillation of firing were modulated by 5HT (2 x 10(-5) M) and mu-opioid peptides (10(-5) M). Co-application of 5HT (2 x 10(-5) M) and DAGO (10(-5) M) turned the firing of the neurons (RPeD1 and A cells) opposite to the running pattern and eliminated the 0.3 Hz oscillation causing a new slow periodicity (0.1-0.05 Hz).
authors.affiliation: Balaton Limnological Research Institute of the Hungarian Academy of Sciences, Tihany. molnarg@tres.blki.hu
authors.forename: G
authors.initials: G
authors.lastname: Molnár
authors.forename: A
authors.initials: A
authors.lastname: Szücs
authors.forename: K S
authors.initials: KS
authors.lastname: Rózsa
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D004594:Electrophysiology; D020875:Enkephalin, Ala(2)-MePhe(4)-Gly(5)- / Q000494:pharmacology; D004744:Enkephalin, Methionine / Q000494:pharmacology; D008195:Lymnaea / Q000502:physiology*; D009415:Nerve Net / Q000187:drug effects / Q000502:physiology*; D012701:Serotonin / Q000494:pharmacology
chemical_list: D020875:Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; D012701:Serotonin; D004744:Enkephalin, Methionine