Early androgenetic alopecia as a marker of insulin resistance.
The previously proven association between androgenetic, alopecia and serious cardiovascular events raises a question of the common pathogenetic mechanism of these disorders. Our practice-based case-control study in men aged 19-50 years showed a strikingly increased risk of hyperinsulinaemia and insulin-resistance-associated disorders such as obesity, hypertension, and dyslipidemia in men with early onset of alopecia (<35), compared with age-matched controls. This finding supports the hypothesis that early androgenetic alopecia could be a clinical marker of insulin resistance.
Matilainen
V
V
Koskela
P
P
Keinänen-Kiukaanniemi
S
S
D000328:Adult; D000505:Alopecia / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics; D000959:Antihypertensive Agents / Q000009:adverse effects; D015415:Biomarkers; D015992:Body Mass Index; D016022:Case-Control Studies; D005387:Finland / Q000453:epidemiology; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
D000959:Antihypertensive Agents; D015415:Biomarkers; D007004:Hypoglycemic Agents