The measurement of efficacy in the drug discovery agonist selection process.
Kenakin
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Department of Receptor Biochemistry, Glaxo Wellcome Research and Development, 5 Moore Drive, Research Triangle Park, NC 27709, USA. tpk1348@glaxo.com
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical / Q000379:methods; D006801:Humans; D008956:Models, Chemical; D008958:Models, Molecular; D011955:Receptors, Drug / Q000819:agonists* / Q000378:metabolism
D011955:Receptors, Drug