Effects of prenatal hypoxia on the formation of immune deficiency in newborn mice.
Fetal hypoxia in the II trimester of pregnancy caused immunodeficiency in newborn mice: inhibition of antibody production to sheep erythrocytes and disturbances in migration of early hemopoietic precursors from the bone marrow to the spleen.
Matrosova
V Y
VY
Institute of Clinical Immunology, Siberian Division, Russian Academy of Medical Sciences, Novosibirsk.
Orlovskaya
I A
IA
Kozlova
D V
DV
Kozlov
V A
VA
D000818:Animals; D000831:Animals, Newborn; D000921:Antibody-Producing Cells / Q000166:cytology*; D016026:Bone Marrow Transplantation; D002452:Cell Count; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D005311:Fetal Hypoxia / Q000276:immunology*; D005865:Gestational Age; D006412:Hematopoietic Stem Cells / Q000378:metabolism*; D022781:Hepatocytes / Q000637:transplantation; D007108:Immune Tolerance; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011247:Pregnancy; D013154:Spleen / Q000166:cytology / Q000276:immunology / Q000637:transplantation