Efficacy of copper oxide needles for the control of nematode parasites in dairy goats.
The spread of benzimidazole-resistant nematodes in dairy goat farms is of a great concern as probably more than 70% of the flocks are involved. As there are very few other anthelmintic options during the lactating period, we have evaluated the efficacy of copper oxide needles (CON, Copinox, Bayer, UK) in both experimental and natural infections in goats. The curative effect of CON (2-4 g) on existing worm burdens was assessed in goats experimentally infected with Teladorsagia circumcincta, Haemonchus contortus and Trichostrongyus colubriformis, compared to controls. The preventive effect of CON (4 g) on worm establishment was monitored for 2 months in animals experimentally infected with H. contortus and for 3 months in naturally infected animals on a farm exhibiting predominant infections with T. circumcincta and Oesophagostomum venulosum. In both experimental and natural conditions, the efficacy of CON was nil against Teladorsagia, Trichostrongylus and Oesophagostomum infections. In contrast, the efficacy of CON against Haemonchus was clearly established in reducing the worm burden (75%) as well as in lowering the egg output (37-95%) in relation to the establishment of new infections over several weeks. Copper oxide needles may represent an alternative to conventional anthelmintics in the control of Haemonchus infection in some goat farms.
Chartier
C
C
AFSSA Niort, Laboratoire de recherches caprines, France. c.chartier@niort.afssa.fr
Etter
E
E
Hoste
H
H
Pors
I
I
Koch
C
C
Dellac
B
B
D000284:Administration, Oral; D000818:Animals; D003300:Copper / Q000008:administration & dosage / Q000627:therapeutic use*; D005243:Feces / Q000469:parasitology; D015511:Goat Diseases / Q000188:drug therapy* / Q000469:parasitology; D006041:Goats; D006188:Haemonchiasis / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary; D006189:Haemonchus / Q000187:drug effects; D009348:Nematoda / Q000187:drug effects*; D009349:Nematode Infections / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D009814:Oesophagostomiasis / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary; D009815:Oesophagostomum / Q000187:drug effects; D010270:Parasite Egg Count / Q000662:veterinary; D011897:Random Allocation; D018709:Statistics, Nonparametric; D014251:Trichostrongyloidea / Q000187:drug effects; D014252:Trichostrongyloidiasis / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary
D003300:Copper; C030973:cupric oxide