title: [The effect of electromagnetic radiation on the monoamine oxidase A activity in the rat brain].
abstract: The effect of the ultralow power pulse-modulated electromagnetic radiation (EMR, power density 10 microW/cm2; carrying frequency 915 MHz; modulating pulses with frequency 2, 4, 6, 8, 12, 16 and 20 Hz) on activity of monoamine oxidase (MAO-A), enzyme involved in the oxidative deamination of monoamines, was investigated. It was established that the increase of activity MAO in hypothalamus reached the maximal meaning at modulation frequency of 6 Hz that corresponded 160% (p < 0.01) of the control level; and at modulation frequency of 20 Hz the decrease of enzyme activity up to 74% (p < 0.01) was found. Mainly the action of ultralow power pulse-modulated EMR on activity of MAO in hippocamp was activating; and the maximal increase of enzyme activity up to 174% (p < 0.01) was registered at modulation frequency of 4 Hz.
authors.affiliation: Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow oblast, Russia. dolgacheva@hotmail.com
authors.forename: L P
authors.initials: LP
authors.lastname: Dolgacheva
authors.forename: T P
authors.initials: TP
authors.lastname: Semenova
authors.forename: B B
authors.initials: BB
authors.lastname: Abzhalelov
authors.forename: I G
authors.initials: IG
authors.lastname: Akoev
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology* / Q000528:radiation effects*; D001923:Brain Chemistry / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D004574:Electromagnetic Fields / Q000009:adverse effects*; D006624:Hippocampus / Q000201:enzymology / Q000528:radiation effects; D007031:Hypothalamus / Q000201:enzymology / Q000528:radiation effects; D008297:Male; D008995:Monoamine Oxidase / Q000032:analysis / Q000528:radiation effects*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D008995:Monoamine Oxidase