title: [Epilepsy presenting as life-threatening events in infants].
abstract: OBJECTIVE
  This study was aimed at assessing the frequency and features of epilepsy presenting as life-threatening events in infancy.
  
  
  METHODS
  Fifteen cases were collected over eight years. Subtle symptoms suggestive of epilepsy were rare (9/15) in the retrospective analysis; the clinical context and cerebral imaging were occasionally contributive (5/15); interictal EEG was useful but inconstantly contributive, including when the epileptic nature of the episodes had become clinically probable (10/15). Though it had no clear relationships with epileptic episodes but contributed to mislead diagnosis, gastroesophageal reflux was frequently associated. Uncovered epilepsies were not homogeneous, ranging from severe epileptic encephalopathy to benign epilepsy of infancy.
  
  
  CONCLUSIONS
  Epilepsy presenting as life-threatening events is sometimes a diagnostic challenge. When an infant develops recurrent critical episodes during a several-week follow-up, with neurological and general investigations not providing more information, the immediate success of antiepileptic treatment might support diagnosis.
authors.affiliation: Service de neurologie pédiatrique, hôpital de Bicêtre, CHU Paris-Sud, Le Kremlin-Bicêtre, France.
authors.forename: L
authors.initials: L
authors.lastname: Heissessen
authors.forename: A
authors.initials: A
authors.lastname: Dusser
authors.forename: V
authors.initials: V
authors.lastname: Nouirygat
authors.forename: Y
authors.initials: Y
authors.lastname: Navelet
authors.forename: A
authors.initials: A
authors.lastname: Charollais
authors.forename: B
authors.initials: B
authors.lastname: Husson
authors.forename: P
authors.initials: P
authors.lastname: Landrieu
mesh_terms: D016638:Critical Illness; D003937:Diagnosis, Differential; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis*; D008297:Male; D012189:Retrospective Studies