Differences Arising in Human Neutrophil Activation Passing from N-Formyl to N-Acetyl-oligopeptides.
N-formyl- and N-acetyl-peptides were synthesized and compared in order to understand which features can best elicit biological responses. The behavior of N-formyl-peptides confirms the previously found sequential obligations in the residues, while acetyl-derivatives do not seem suitable for an efficacious stimulation of human neutrophils. Copyright 2000 Academic Press.
Spisani
S
Department of Biochemistry and Molecular Biology
Cavicchioni
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