title: [A case of advanced rectal cancer with unresectable liver metastasis for which chemotherapy was markedly effective].
abstract: We report a case of advanced rectal cancer accompanied by unresectable liver metastasis in which remission has been achieved for 7 years. The patient was a 64-year-old woman, and her chief complaints were a feeling of abdominal distention and melena. After low anterior resection (D3), oral administration of 600 mg/day of UFT-E and chemotherapy against the liver metastasis by hepatic arterial injection via a reservoir were started. Since the arterial injection via a reservoir became impossible due to infection, her clinical course was observed solely with oral administration of UFT-E. As a result, complete remission was achieved 7 months postoperatively, and the patient is still alive in good health without recurrences at present (7 years postoperatively). The reason why a favorable outcome has been achieved is probably that, although the initial operation resulted is non-curative resection, measures sufficient to enable the patient to lead an ordinary social life were taken at the beginning, and efforts to achieve a long-term survival were made while respecting the quality of life of the patient so that the patient would be able to coexist with the cancer.
authors.affiliation: Dept. of Surgery, Hino Municipal General Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Kikunaga
authors.forename: K
authors.initials: K
authors.lastname: Sotome
authors.forename: A
authors.initials: A
authors.lastname: Morisue
authors.forename: A
authors.initials: A
authors.lastname: Matsudo
authors.forename: H
authors.initials: H
authors.lastname: Baba
authors.forename: H
authors.initials: H
authors.lastname: Nakai
authors.forename: M
authors.initials: M
authors.lastname: Takao
authors.forename: Y
authors.initials: Y
authors.lastname: Osakabe
authors.forename: H
authors.initials: H
authors.lastname: Miura
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D000284:Administration, Oral; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D015918:Infusion Pumps, Implantable; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D012074:Remission Induction; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
chemical_list: D005641:Tegafur; D016685:Mitomycin; D014498:Uracil; D005472:Fluorouracil