The use of adjuvant interferon-gamma therapy for hepatosplenic Blastoschizomyces capitatus infection in a patient with leukemia.
Hepatosplenic fungal infections are a devastating complication of neutropenia. Despite aggressive antifungal therapy, clinical response may be poor. We describe a case of hepatosplenic Blastoschizomyces capitatus infection that responded to adjuvant interferon-gamma therapy.
DeMaio
J
J
Infections Limited, Tacoma, WA 98405, USA. jdemaio@idlinks.com
Colman
L
L
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D006801:Humans; D007371:Interferon-gamma / Q000627:therapeutic use*; D008107:Liver Diseases / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D009181:Mycoses / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D004718:Saccharomycetales / Q000187:drug effects* / Q000302:isolation & purification; D013158:Splenic Diseases / Q000188:drug therapy / Q000382:microbiology; D016896:Treatment Outcome
D000970:Antineoplastic Agents; D007371:Interferon-gamma