[Comparison of propofol and isoflurane anesthesia on postoperative nausea, vomiting and pruritus induced by epidural morphine].
We compared propofol-nitrous oxide anesthesia (Group P) with isoflurane-nitrous oxide anesthesia (Group I) on the incidence of postoperative nausea, vomiting and pruritus induced by epidural morphine. Twenty-eight patients for thoracotomy for lung surgeries were randomly assigned either to Group P or Group I. All patients were administrated epidural morphine (4-7 mg.day-1) during and after the operation. The incidence of nausea, vomiting and pruritus was evaluated at the postoperative early (< 9 hour) and late (> 9 hour) periods. In the late postoperative period, in Group P the incidence of nausea and vomiting tended to be low compared with Group I, but the difference was not statistically significant. The incidence of pruritus was not different between the two groups in both early and late periods.
Matsumura
Y
Y
Department of Anesthesia, Toneyama National Sanatorium, Toyonaka.
Matsubara
Y
Y
Uchida
I
I
Mashimo
T
T
Yoshiya
I
I
D000368:Aged; D015360:Analgesia, Epidural; D000768:Anesthesia, General; D005260:Female; D006801:Humans; D007530:Isoflurane; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000009:adverse effects*; D010149:Postoperative Pain / Q000188:drug therapy; D011183:Postoperative Complications / Q000139:chemically induced; D020250:Postoperative Nausea and Vomiting / Q000139:chemically induced* / Q000517:prevention & control; D015742:Propofol; D011537:Pruritus / Q000139:chemically induced* / Q000517:prevention & control
D009020:Morphine; D007530:Isoflurane; D015742:Propofol