title: The construction of the first balancer chromosome for the Mediterranean fruit fly, Ceratitis capitata.
abstract: The construction of the first balancer chromosome, FiM1, for the medfly Ceratitis capitata is described. This chromosome has three overlapping pericentric inversions and is marked with dominant and recessive mutations. The inversion breakpoints of FiM1 suppress recombination throughout the length of the fifth chromosome, allowing lethal mutations to be recovered and maintained. This chromosome will provide a powerful tool for the manipulation of laboratory stocks, in particular, the recovery of new mutant and transgenic strains. We demonstrate the use of FiM1 for the recovery and maintenance of chromosomes carrying lethal mutations.
authors.affiliation: Department of Biology, University of Patras, Greece.
authors.forename: P
authors.initials: P
authors.lastname: Gourzi
authors.forename: D
authors.initials: D
authors.lastname: Gubb
authors.forename: Y
authors.initials: Y
authors.lastname: Livadaras
authors.forename: C
authors.initials: C
authors.lastname: Caceres
authors.forename: G
authors.initials: G
authors.lastname: Franz
authors.forename: C
authors.initials: C
authors.lastname: Savakis
authors.forename: A
authors.initials: A
authors.lastname: Zacharopoulou
mesh_terms: D000818:Animals; D002869:Chromosome Aberrations; D007446:Chromosome Inversion; D002875:Chromosomes; D004175:Diptera / Q000235:genetics*; D005260:Female; D005298:Fertility / Q000235:genetics; D005804:Genes, Lethal; D005808:Genes, Recessive; D005819:Genetic Markers; D005821:Genetic Techniques; D008297:Male; D009154:Mutation; D011995:Recombination, Genetic
chemical_list: D005819:Genetic Markers