title: Efficacy of a commercially available coryza vaccine against challenge with recent South African NAD-independent isolates of Haemophilus paragallinarum in chickens.
abstract: In South Africa the incidence of NAD-independent Haemnophilus paragallinarum isolation from clinical cases is increasing. This study was carried out to test whether a commercially available coryza vaccine (Nobilis Coryza, Intervet International BV) could protect chickens against challenge with recent NAD-independent isolates. SPF chickens were vaccinated twice at 3 and 7 weeks of age and were challenged at 9 weeks of age with 5 different NAD-independent isolates of serotype A or C-3. The results after challenge show that the coryza vaccine induces good protection against challenge with the different South African NAD-independent isolates of H. paragallinarum, including serotype C-3.
authors.affiliation: Bacteriological R&D, Intervet International BV, Boxmeer, The Netherlands. ton.jacobs@intervet.com
authors.forename: A A
authors.initials: AA
authors.lastname: Jacobs
authors.forename: J
authors.initials: J
authors.lastname: van der Werf
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D001428:Bacterial Vaccines; D002645:Chickens; D006190:Haemophilus / Q000276:immunology*; D006192:Haemophilus Infections / Q000517:prevention & control / Q000662:veterinary*; D007117:Immunization, Secondary / Q000662:veterinary; D009243:NAD / Q000302:isolation & purification; D011201:Poultry Diseases / Q000517:prevention & control*; D013019:South Africa; D013047:Specific Pathogen-Free Organisms; D014611:Vaccination / Q000662:veterinary
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D009243:NAD