Comparison of quinapril versus atenolol: effects on blood pressure and cardiac mass after renal transplantation.
Based on epidemiologic facts on elevated cardiovascular mortality in renal allograft recipients, an echocardiographic 2-year follow-up in hypertensive renal allograft recipients was conducted. This study provides evidence that, in contrast to atenolol, quinapril, independent of blood pressure reduction, reduces left ventricular hypertrophy and improves left ventricular diastolic function in this population.
Suwelack
B
B
Medical Department D, University of Münster, Germany. suwelac@uni-muenster.de
Gerhardt
U
U
Hausberg
M
M
Rahn
K H
KH
Hohage
H
H
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology* / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000494:pharmacology / Q000627:therapeutic use; D001262:Atenolol / Q000494:pharmacology* / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects*; D003971:Diastole / Q000187:drug effects; D004311:Double-Blind Method; D006352:Heart Ventricles / Q000033:anatomy & histology / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D017379:Hypertrophy, Left Ventricular / Q000188:drug therapy*; D007546:Isoquinolines / Q000494:pharmacology* / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000502:physiology*; D008875:Middle Aged; D000077583:Quinapril; D044005:Tetrahydroisoquinolines; D016276:Ventricular Function
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D007546:Isoquinolines; D044005:Tetrahydroisoquinolines; D001262:Atenolol; D000077583:Quinapril