title: Severe self-injurious behavior associated with treatment-resistant schizophrenia: treatment with maintenance electroconvulsive therapy.
abstract: A 35-year-old man with schizophrenia associated with a 10-year history of repetitive and often severe self-injurious behaviors was treated successfully with maintenance electroconvulsive therapy. Initially his condition did not respond to multiple psychotropic agents (including a year-long trial of clozapine), 27 hospitalizations, two courses of bilateral electroconvulsive therapy, and supportive psychotherapy with partial hospitalization. After the initiation of maintenance electroconvulsive therapy, this patient was able to tolerate residential placement and begin a work therapy program with only one instance of self-injurious behavior in the past 17 months.
authors.affiliation: Minneapolis Veterans Administration Hospital, Minneapolis MN 55417, USA. cdean@black-hole.com
authors.forename: C E
authors.initials: CE
authors.lastname: Dean
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D003024:Clozapine / Q000627:therapeutic use; D004351:Drug Resistance; D004565:Electroconvulsive Therapy; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D008297:Male; D018967:Risperidone / Q000627:therapeutic use; D012559:Schizophrenia / Q000628:therapy*; D012565:Schizophrenic Psychology; D016728:Self-Injurious Behavior / Q000150:complications*
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine; D006220:Haloperidol; D018967:Risperidone