title: [A case of Wegener's granulomatosis with pachymeningitis].
abstract: A 62-year-old woman who had been receiving corticosteroid therapy for pachymeningitis since 1997 was admitted to our hospital when an abnormal shadow was noticed in her chest radiograph. In bronchial and nasal mucosal biopsies, the findings of a necrotic granulomatous lesion and vasculitis were compatible with Wegener's granulomatosis, although this is rarely seen with pachymeningitis. After further corticosteroid therapy together with cyclophosphamide treatment, the size of the thoracic X-ray shadow decreased. Methicillin-resistant Staphylococcus aureus (MRSA) was cultured from the sputum and the nasal fluid, and may have contributed to the advance of the disease in the airway. This case will require continuing careful observation.
authors.affiliation: Second Department of Internal Medicine, Nagoya City University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Niimi
authors.forename: Y
authors.initials: Y
authors.lastname: Sugiura
authors.forename: S
authors.initials: S
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Yoshinouchi
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Akita
authors.forename: H
authors.initials: H
authors.lastname: Maeda
authors.forename: T
authors.initials: T
authors.lastname: Mori
authors.forename: H
authors.initials: H
authors.lastname: Kawaguchi
authors.forename: M
authors.initials: M
authors.lastname: Morishita
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
authors.forename: R
authors.initials: R
authors.lastname: Ueda
mesh_terms: D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications*; D006801:Humans; D008581:Meningitis / Q000150:complications*; D008875:Middle Aged