title: Foldable silicone versus poly(methyl methacrylate) intraocular lenses in combined phacoemulsification and trabeculectomy.
abstract: OBJECTIVE
  To compare the outcome of phacotrabeculectomy with implantation of poly(methyl methacrylate) (PMMA) or foldable silicone intraocular lenses (IOLs).
  
  
  METHODS
  Thirty patients were randomized to receive a 5.5 mm PMMA IOL through a 5.0 mm incision or a foldable silicone IOL (Allergan SI-30) through a 3.2 mm incision. Visual acuity, intraocular pressure (IOP), bleb survival, inflammation, endothelial cell changes, and complications were examined at intervals up to 6 months.
  
  
  RESULTS
  There was no difference between the 2 groups in final visual outcome, final IOP control, bleb survival, and endothelial cell changes. Two months after surgery, there was significantly more inflammation in the silicone IOL group than in the PMMA group (P <. 05). The silicone group had a significantly higher combined complication rate including iris capture, choroidal effusion, and epiretinal membrane formation (P <.05).
  
  
  CONCLUSIONS
  Foldable silicone IOLs were comparable to conventional PMMA lenses in visual outcome, IOP control, bleb formation, and endothelial changes. However, some silicone lenses are associated with an increased risk of recurrence of inflammation and a higher final complication rate in combined cataract and filtration surgery.
authors.affiliation: University of Toronto, Toronto Hospital (Western Division), Toronto, Ontario, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Braga-Mele
authors.forename: S
authors.initials: S
authors.lastname: Cohen
authors.forename: D S
authors.initials: DS
authors.lastname: Rootman
mesh_terms: D000368:Aged; D002386:Cataract / Q000150:complications*; D003315:Cornea / Q000166:cytology; D005901:Glaucoma / Q000150:complications / Q000601:surgery*; D006801:Humans; D007431:Intraoperative Complications; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D018918:Phacoemulsification; D019904:Polymethyl Methacrylate; D011183:Postoperative Complications; D011446:Prospective Studies; D012826:Silicone Elastomers; D014130:Trabeculectomy; D014792:Visual Acuity
chemical_list: D012826:Silicone Elastomers; D019904:Polymethyl Methacrylate