title: Pulmonary lymphomatoid granulomatosis in a cat.
abstract: Pulmonary lymphomatoid granulomatosis was diagnosed in a 9-year-old castrated male domestic shorthair cat with a history of coughing, lethargy, and anorexia. Radiographic examination revealed multiple pulmonary opacities, consolidation of left lung lobes, and enlarged tracheobronchial lymph nodes. Cytologic examination of impression smears of abnormal pulmonary tissue revealed erythrocytes, lymphocytes, and macrophages, with scattered atypical lymphocytes and binucleate cells. Histopathologic evaluation of abnormal lung tissue revealed multiple, coalescing, densely cellular nodules composed of anaplastic and pleomorphic lymphocytes, with scattered binucleate and multinucleate cells. Marked infiltration and effacement of bronchiolar and vascular smooth muscle were present. These features are characteristic of lymphomatoid granulomatosis. To the authors' knowledge, this is the first report of pulmonary lymphomatoid granulomatosis in a cat.
authors.affiliation: Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6401, USA.
authors.forename: B A
authors.initials: BA
authors.lastname: Valentine
authors.forename: J T
authors.initials: JT
authors.lastname: Blue
authors.forename: J F
authors.initials: JF
authors.lastname: Zimmer
authors.forename: A E
authors.initials: AE
authors.lastname: Yeager
authors.forename: S P
authors.initials: SP
authors.lastname: McDonough
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D008168:Lung / Q000166:cytology / Q000473:pathology*; D008171:Lung Diseases / Q000473:pathology / Q000662:veterinary*; D008230:Lymphomatoid Granulomatosis / Q000473:pathology / Q000662:veterinary*; D008297:Male