title: Transrenal fixation of aortic stent-grafts for the treatment of infrarenal aortic aneurysmal disease.
abstract: OBJECTIVE
  We evaluated our early experience with the transrenal fixation of aortic stent-grafts to determine the efficacy of this procedure and its effects on renal artery patency and hemodynamics.
  
  
  METHODS
  Twenty-eight patients (22 men) had endoluminally placed modular bifurcated stent-grafts with a bare spring structure at the proximal end crossing the origin of both renal arteries; no patient with infrarenal fixation was included for analysis. The mean age of the patients was 75 +/- 7 years (range, 58-86 years); the mean aneurysm size was 5.8 +/- 0.8 cm (range, 4.7-7.2 cm). Eight patients had preoperative or intraoperative angiographic evidence of renal artery atherosclerotic disease, but only four vessels had luminal narrowing of 50% or greater. No complications were noted during stent-graft placement, and all patients have returned for follow-up visits, ranging from 1 to 12 months (mean follow-up, 6 +/- 4 months). Follow-up evaluations included clinical assessment, duplex ultrasound scan of the renal arteries and kidneys, and computed tomographic angiography.
  
  
  RESULTS
  No evidence of lobular or sublobular perfusion defects of the renal parenchyma was detected postoperatively. Two patients exhibited postoperative changes in renal artery hemodynamics-one progressing from a 30% diameter reduction to a greater than 60% diameter stenosis at the 12-month follow-up visit and one with a normal renal artery preoperatively having elevated flow velocities indicative of a greater than 60% stenosis at the 1-month visit. Of 19 patients with normal preoperative renal function, only one has had persistently elevated serum creatinine levels.
  
  
  CONCLUSIONS
  We conclude from this experience that the transrenal placement of open stents is safe and effectively excludes the aneurysm, potentially expanding the availability of this technique to more patients with a short infrarenal aortic neck. Long-term follow-up is essential to determine the overall efficacy of this technique and to identify potential effects on renal artery hemodynamics or kidney function.
authors.affiliation: Department of Surgery, William Beaumont Hospital, Royal OAk, MI 48073, USA. pbove@beaumont.edu
authors.forename: P G
authors.initials: PG
authors.lastname: Bove
authors.forename: G W
authors.initials: GW
authors.lastname: Long
authors.forename: G B
authors.initials: GB
authors.lastname: Zelenock
authors.forename: P J
authors.initials: PJ
authors.lastname: Bendick
authors.forename: M D
authors.initials: MD
authors.lastname: Khoury
authors.forename: M O
authors.initials: MO
authors.lastname: Burr
authors.forename: G
authors.initials: G
authors.lastname: Bechtel
authors.forename: F
authors.initials: F
authors.lastname: Becker
authors.forename: C
authors.initials: C
authors.lastname: Huckabone
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D012078:Renal Artery Obstruction / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D015607:Stents; D016896:Treatment Outcome