title: Neutropenia accompanying parvovirus B19 infection after gynecologic surgery.
abstract: The hematologic data and symptoms of 7 patients seropositive for parvovirus B19 IgM antibody after gynecologic surgery were analysed. Parvovirus may have been transmitted by fibrin glue prepared from heat-treated human plasma and used for hemostasis during surgery. The peripheral blood neutrophil count decreased to below 1 x 10(9)/l between postoperative day (POD) 10 and 18, but recovered spontaneously to within the normal range. G-CSF injection was effective in preventing neutropenia or obtaining a prompt recovery. The reticulocyte count fell below 10 x 10(9)/l between POD 13 and 19, and also recovered spontaneously. A slapped-cheek rash was not observed in any of the 7 patients.
authors.affiliation: Department of Obstetrics and Gynecology, Osaka City University Medical School, Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Honda
authors.forename: O
authors.initials: O
authors.lastname: Ishiko
authors.forename: A
authors.initials: A
authors.lastname: Tsujimura
authors.forename: M
authors.initials: M
authors.lastname: Hino
authors.forename: K
authors.initials: K
authors.lastname: Hirai
authors.forename: F
authors.initials: F
authors.lastname: Itoh
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Ogita
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D001772:Blood Cell Count; D002648:Child; D005260:Female; D005334:Fever / Q000821:virology; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology / Q000627:therapeutic use; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects*; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D009503:Neutropenia / Q000821:virology*; D009504:Neutrophils / Q000166:cytology / Q000187:drug effects / Q000821:virology; D010322:Parvoviridae Infections / Q000150:complications* / Q000209:etiology; D016732:Parvovirus B19, Human / Q000276:immunology; D013997:Time Factors
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M; D016179:Granulocyte Colony-Stimulating Factor