Possible different fates for the hydrogen peroxide produced by rat white adipocyte amine oxidases.
Monoamine oxidase (MAO) and benzylamine oxidases (Bz-SSAO) of rat white adipocytes, deaminating benzylamine and tyramine produce hydrogen peroxide at different cellular levels. The peroxide produced by their activity has a very short half-life in adipocyte suspension. The addition of a catalase inhibitor allows for the recovery of the intact peroxide within the first 10-min of its production. Thus, benzylamine and tyramine-dependent peroxide recovery is different, suggesting that the fate of the peroxide produced by the two amine oxidases might be different depending on the cellular site of its production.
Raimondi
L
L
Dept. of Pharmacology, University of Florence, Italy.
Banchelli
G
G
Sgromo
L
L
Pirisino
R
R
D017667:Adipocytes / Q000201:enzymology*; D000818:Animals; D001595:Benzylamine Oxidase / Q000378:metabolism*; D006861:Hydrogen Peroxide / Q000378:metabolism*; D008297:Male; D008995:Monoamine Oxidase / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D014439:Tyramine / Q000378:metabolism*
D006861:Hydrogen Peroxide; D001595:Benzylamine Oxidase; D008995:Monoamine Oxidase; D014439:Tyramine