title: [Effect of ecdystene on parameters of the sexual function under experimental and clinical conditions].
abstract: The effects of ecdysterone and the related drug ecdysten on the sexual activity were studied under experimental and clinical conditions. A 10-day administration of ecdysterone (5 and 10 mg/kg, p.o.) improved behavioral characteristics of the sexual function in rats, the effect being especially pronounced during the fist days of experiment. The administration of ecdysten to men with the infertility diagnosis (disturbed spermatogenesis as a complication of some urologic diseases) increased the copulative function and improved the sperm quality. The administration of ecdysten to patients in the stage of recovery upon myocardial infarction also improved the sexual function.
authors.affiliation: Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan.
authors.forename: Iu R
authors.initials: IuR
authors.lastname: Mirzaev
authors.forename: V N
authors.initials: VN
authors.lastname: Syrov
authors.forename: S A
authors.initials: SA
authors.lastname: Khrushev
authors.forename: S D
authors.initials: SD
authors.lastname: Iskanderova
mesh_terms: D000222:Adaptation, Physiological / Q000187:drug effects; D000818:Animals; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy* / Q000523:psychology; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000523:psychology*; D010936:Plant Extracts / Q000494:pharmacology; D051381:Rats; D012725:Sexual Behavior / Q000187:drug effects*; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D013094:Spermatozoa / Q000187:drug effects / Q000473:pathology; D013256:Steroids / Q000494:pharmacology*
chemical_list: D010936:Plant Extracts; D013256:Steroids; C088647:ecdystene