title: [Differentiated approaches to the treatment of nonstabilized primary open-angle glaucoma with normalized intraocular pressure considering its pathogenic features].
abstract: Clinical efficiency of dedystrophic treatments for nonstabilized primary open-angle glaucoma (POAG) in the presence of normalized intraocular pressure is compared in 168 patients (246 eyes). In one group of patients ischemic angiopathy and hyperreactivity of optic vessel adrenoreceptors associated with hypokinetic central hemodynamics and constitutional metabolic status of the organism was corrected by cinnarisin and riboxin. Patients with predominating congestive angiopathy symptoms, hyper- or eukinetic circulation and "slow" acetylation were treated by pantothenic acid, endotelon, and hyperbaric oxygenation. In both groups epithalamine, eiconol, and magnetic laser therapy were used, if indicated. This helped stabilize the process in 91% patients with initial POAG, in 87.5% with well-developed condition vs. 66.1% and 38.2% patients treated by traditional therapy (period of observation 3 years).
authors.forename: V V
authors.initials: VV
authors.lastname: Egorov
authors.forename: E L
authors.initials: EL
authors.lastname: Sorokin
authors.forename: G P
authors.initials: GP
authors.lastname: Smoliakova
mesh_terms: D000368:Aged; D000975:Antioxidants / Q000627:therapeutic use; D044946:Biflavonoids; D002392:Catechin / Q000627:therapeutic use; D004042:Dietary Fats, Unsaturated / Q000627:therapeutic use; D005260:Female; D005395:Fish Oils / Q000627:therapeutic use; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D007290:Inosine Diphosphate / Q000627:therapeutic use; D007429:Intraocular Pressure; D053685:Laser Therapy; D008280:Magnetics / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010205:Pantothenic Acid / Q000627:therapeutic use; D044945:Proanthocyanidins; D013997:Time Factors; D014792:Visual Acuity
chemical_list: D000975:Antioxidants; D044946:Biflavonoids; D004042:Dietary Fats, Unsaturated; D005395:Fish Oils; D000960:Hypolipidemic Agents; D044945:Proanthocyanidins; C089938:eiconol; D010205:Pantothenic Acid; C017674:procyanidin; C479585:procyanidol oligomer; D007290:Inosine Diphosphate; D002392:Catechin