A case of chronic adrenocortical insufficiency with iatrogenic anasarca.
The decrease in active hormones that characterizes chronic adrenal insufficiency results in hypovolemia. In some patients, residual adrenal function, mineralocorticoid therapy, and concomitant heart or liver failure, or both, can paradoxically provoke edema. The case report that follows describes a patient with iatrogenically induced anasarca resulting from the unhappy confluence of usually appropriate therapy and coexisting medical conditions.
Parlapiano
C
C
Department of Clinical Endocrinology, University of Rome La Sapienza, Italy.
Campana
E
E
Pantone
P
P
Giovanniello
T
T
Borgia
M C
MC
D000224:Addison Disease / Q000188:drug therapy*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003348:Cortisone / Q000009:adverse effects / Q000031:analogs & derivatives*; D004487:Edema / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use
D000894:Anti-Inflammatory Agents, Non-Steroidal; D003348:Cortisone; D011241:Prednisone