title: Immune function of small bowel and its related diseases.
abstract: The small intestine is a major immunological organ with aggregated lymphoid tissue of Peyer's diffuse lymphoid tissue of lamina propria and intra-epithelial lymphocytes as 3 key components. Immunopathogenesis is of central importance for coeliac disease, Crohn's disease and gastrointestinal food allergy. Small intestinal enteropathy of variable severity, related to T-cell activation is common to all.
authors.affiliation: University Department of Paediatric Gastroenterology, Royal Free Campus, London, U.K.
authors.forename: J A
authors.initials: JA
authors.lastname: Walker-Smith
mesh_terms: D002446:Celiac Disease / Q000276:immunology* / Q000628:therapy; D003424:Crohn Disease / Q000276:immunology* / Q000628:therapy; D005512:Food Hypersensitivity / Q000276:immunology* / Q000628:therapy; D006801:Humans; D007421:Intestine, Small / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology