title: [Oncovirus-induced permanent genetic instability in Drosophila melanogaster].
abstract: Mutant alleles of a system of genetic instability induced by oncoviral DNAs were shown to demonstrate an unstable manifestation 500 generations after their emergence. A cytogenetic analysis of oncovirus-induced unstable lines has revealed numerous chromosome rearrangements. For the Lobe alleles of this system, a specific chromosome rearrangement, Df(2L) = 35C-36B, was found on the left arm of chromosome 2. We used recessive lethal mutations involving DNA rearrangements in a successful construction of cross systems for "explosive" instability.
authors.affiliation: Department of Genetics and Molecular Biology, Al-Farabi State University Kazakhstan, Almaty.
authors.forename: N V
authors.initials: NV
authors.lastname: Mit'
authors.forename: L B
authors.initials: LB
authors.lastname: Dzhansugurova
authors.forename: R I
authors.initials: RI
authors.lastname: Bersimbaev
mesh_terms: D000483:Alleles; D000818:Animals; D004279:DNA, Viral; D004331:Drosophila melanogaster / Q000235:genetics* / Q000821:virology; D009154:Mutation; D012190:Retroviridae / Q000235:genetics / Q000502:physiology*
chemical_list: D004279:DNA, Viral