title: Estimating the dose variation in a volume of interest with explicit consideration of patient geometric variation.
abstract: A method to measure the effects of internal organ motion and deformation and patient setup error on cumulative dose variation in a volume of interest is proposed. The method uses multiple CT scans and electronic portal images of a single patient to numerically simulate dose-volume effects over the entire course of the patient's external beam treatment. The results are expressed in the form of a novel dose-volume histogram, called an expected dose-volume histogram (EDVH).
authors.affiliation: William Beaumont Hospital, Department of Radiation Oncology, Royal Oak, Michigan 48073-6769, USA. dlockman@beaumont.edu
authors.forename: D M
authors.initials: DM
authors.lastname: Lockman
authors.forename: D
authors.initials: D
authors.lastname: Yan
authors.forename: J
authors.initials: J
authors.lastname: Wong
mesh_terms: D006801:Humans; D008962:Models, Theoretical; D009068:Movement; D011874:Radiometry / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted; D015203:Reproducibility of Results; D012984:Software