title: [A case of non-small-cell lung cancer successfully treated using combination chemotherapy with CDDP and vinorelbine].
abstract: A 67-year-old woman presented to our hospital with a chief complaint of bloody sputum. A plain chest X-ray a CT scan revealed a tumor shadow 3 cm in size in the middle lobe of the right lung, multiple nodular shadows in the bilateral lung fields and enlarged hilar and mediastinal lymph nodes. A tumor biopsy done under bronchoscopy revealed poorly differentiated adenocarcinoma of the lungs (cT2N3M1). She was given two courses of combination therapy consisting of cisplatin (80 mg/m2) and vinorelbine (20 mg/m2). The primary tumor in the middle lobe of the right lung and the lung metastases were markedly reduced in size, and a complete response was obtained. The only adverse events were grade 4 neutropenia and grade 2 nausea and vomiting.
authors.affiliation: Dept. of Internal Medicine, Saiseikai Kanagawaken Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Shimizu
authors.forename: E
authors.initials: E
authors.lastname: Watanabe
authors.forename: S
authors.initials: S
authors.lastname: Hamanaka
authors.forename: S
authors.initials: S
authors.lastname: Onuma
authors.forename: M
authors.initials: M
authors.lastname: Nakano
authors.forename: T
authors.initials: T
authors.lastname: Yamazaki
authors.forename: M
authors.initials: M
authors.lastname: Higa
authors.forename: W
authors.initials: W
authors.lastname: Yamamuro
authors.forename: E
authors.initials: E
authors.lastname: Kiguchi
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D014747:Vinblastine / Q000031:analogs & derivatives
chemical_list: D014747:Vinblastine; D002945:Cisplatin