title: Highly enantioselective addition of diethylzinc to diphenylphosphinoyl imines under dual amino Alcohol/Halosilane mediation
abstract: Arylethylene-derived, enantiomerically pure amino alcohols have been evaluated as ligands for the dual-catalyzed (amino alcohol/halosilane) enantioselective addition of diethylzinc to diphenylphosphinoyl imines. Among them, the conformationally restricted 9-fluorenone-derived ligand 4c provides the highest enantioselectivities so far reported over a range of substrate imines.
authors.affiliation: Unitat de Recerca en Sintesi Asimetrica, Departament de Quimica Organica, Universitat de Barcelona, c/Marti i Franques 1-11, E-08028 Barcelona, Spain.
authors.initials: C
authors.lastname: Jimeno
authors.initials: KS
authors.lastname: Reddy
authors.initials: L
authors.lastname: Sola
authors.initials: A
authors.lastname: Moyano
authors.initials: MA
authors.lastname: Pericas
authors.initials: A
authors.lastname: Riera