[Immunomodulation of pain].
Review of the interacting elements of nociceptive, neuroimmune and neuroendocrine systems with a stress on sympathetic innervation of the lymphoid organs. Special attention is given to dysfunctions within the nociceptive, neuroendocrine and immune systems due to: damage to the: 1) afferent fibers; 2) sympatho-adrenal system; 3) structure of the hypothalamo-pituitary-adrenal axis. The role of peripheral immunocytes in the generation of pain, including local cytokines, opioids and CRF is also discussed.
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Katedra i Zakład Anatomii Prawidłowej Akademii Medycznej im. K. Marcinkowskiego w Poznaniu.
D000276:Adjuvants, Immunologic / Q000378:metabolism; D000818:Animals; D016207:Cytokines / Q000378:metabolism; D006801:Humans; D009294:Narcotics / Q000378:metabolism; D010146:Pain / Q000276:immunology*; D013564:Sympathetic Nervous System / Q000502:physiology
D000276:Adjuvants, Immunologic; D016207:Cytokines; D009294:Narcotics