The effect of sedative drugs on diaphragmatic contractility in dogs: propofol versus midazolam.
a sedative dose (0.1 mg x kg(-1) x h(-1)) of midazolam, compared with a subhypnotic dose (1.5 mg x kg(-1) x h(-1)) of propofol, decreases the contractility of the diaphragm in dogs.
Fujii
Y
Y
Department of Anesthesiology, University of Tsukuba Institute of Clinical Medicine, Tsukuba City, Ibaraki, Japan.
Hoshi
T
T
Takahashi
S
S
Toyooka
H
H
D000704:Analysis of Variance; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D003964:Diaphragm / Q000187:drug effects* / Q000294:innervation; D004285:Dogs; D004558:Electric Stimulation; D006339:Heart Rate / Q000187:drug effects; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D007260:Infusion Pumps; D007262:Infusions, Intravenous; D007275:Injections, Intravenous; D007442:Intubation, Intratracheal; D007537:Isometric Contraction / Q000187:drug effects; D008874:Midazolam / Q000008:administration & dosage / Q000494:pharmacology*; D009119:Muscle Contraction / Q000187:drug effects*; D010791:Phrenic Nerve / Q000502:physiology; D015742:Propofol / Q000008:administration & dosage / Q000494:pharmacology*; D011897:Random Allocation; D012121:Respiration, Artificial
D006993:Hypnotics and Sedatives; D008874:Midazolam; D015742:Propofol