Train of four fade in a child with stiff baby syndrome.
A case is described of a child with stiff baby syndrome who underwent open reduction and femoral shortening of congenital dislocated hip under general anaesthesia. Neuromuscular function was measured electromyographically and demonstrated a great degree of train of four fade (57%) after sevoflurane inhalational induction of anaesthesia. The response to suxamethonium (2 mg x kg(-1)) was normal. The neuromuscular response to volatile anaesthetic agents and suxamethonium may be abnormal in these children with stiff baby syndrome and intraoperative neuromuscular monitoring is recommended.
Murphy
C
C
Department of Anaesthesia and Intensive Care Medicine, Cork University Hospital and University College Cork, Ireland.
Shorten
G
G
D000768:Anesthesia, General; D004558:Electric Stimulation; D004576:Electromyography; D005260:Female; D006801:Humans; D007223:Infant; D009467:Neuromuscular Depolarizing Agents; D010147:Pain Measurement; D016750:Stiff-Person Syndrome / Q000503:physiopathology*; D013390:Succinylcholine
D009467:Neuromuscular Depolarizing Agents; D013390:Succinylcholine