title: Kimura's disease presenting as subcutaneous facial plaque in an African American.
abstract: Kimura's disease is a benign, uncommon, chronic inflammatory condition that usually presents with painless subcutaneous nodules or plaques in the head and neck region. Although the disease is predominantly found in Asian populations, there are occasional cases reported among Caucasians and rare occurrences in African populations. The etiology and pathogenesis of the disease are unknown and the clinical presentation can mimic several benign and malignant disease states. The accurate diagnosis of Kimura's disease is based on clinical and histopathological findings. There is no evidence of malignant transformation and occasional spontaneous resolution occurs. Various treatment modalities have been suggested in the management of this condition. Oral corticosteroids have been the mainstay of therapy, even though steroid withdrawal can result in lesion recurrence.
authors.affiliation: Department of Family Medicine, University of Kansas Medical Center, Kansas City 66160-7370, USA. tdaalema@kumc.edu
authors.forename: T P
authors.initials: TP
authors.lastname: Daaleman
authors.forename: J
authors.initials: J
authors.lastname: Woodroof
mesh_terms: D000328:Adult; D001741:Black or African American; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000208:ethnology* / Q000473:pathology; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000208:ethnology* / Q000473:pathology; D006801:Humans; D008297:Male