title: Control of fleas on naturally infested dogs and cats and in private residences with topical spot applications of fipronil or imidacloprid.
abstract: Thirty-four flea-infested dogs and cats residing in 20 homes in Tampa, FL were randomly placed into 1 of 2 treatment groups during the summer of 1997. Pets were treated topically with either 10.0%w/v imidacloprid or 10%w/v fipronil spot-on on day 0, then once for every 28-30 days for 90 days. Flea populations were assessed in the environment using an intermittent-light trap, while pet flea burdens were assessed using visual area counts. A single application of imidacloprid was 95.3 and 97.4% effective in reducing flea populations on pets at 7 and 28 days, respectively. A single application of fipronil was 97.5 and 97.0% effective in reducing flea populations on pets at the same time points. Following 3 monthly applications of either imidacloprid or fipronil, flea burdens on pets were reduced by 99.5 and 96.5%, respectively. In addition, flea numbers in the in-home environment were reduced by 99. 0 and 98.6% in homes, where pets were treated with imidacloprid or fipronil, respectively.
authors.affiliation: Department of Diagnostic Medicine/Pathobiology, 1800 Denison Avenue, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA. dryden@vet.ksu.edu
authors.forename: M W
authors.initials: MW
authors.lastname: Dryden
authors.forename: T M
authors.initials: TM
authors.lastname: Denenberg
authors.forename: S
authors.initials: S
authors.lastname: Bunch
mesh_terms: D000287:Administration, Topical; D000818:Animals; D002371:Cat Diseases / Q000517:prevention & control*; D002415:Cats; D004283:Dog Diseases / Q000517:prevention & control*; D004285:Dogs; D004478:Ectoparasitic Infestations / Q000188:drug therapy / Q000662:veterinary*; D007093:Imidazoles / Q000008:administration & dosage / Q000627:therapeutic use*; D007300:Insect Control; D007306:Insecticides / Q000008:administration & dosage / Q000627:therapeutic use*; D000073943:Neonicotinoids; D009574:Nitro Compounds; D011720:Pyrazoles / Q000008:administration & dosage / Q000627:therapeutic use*; D005423:Siphonaptera
chemical_list: D007093:Imidazoles; D007306:Insecticides; D000073943:Neonicotinoids; D009574:Nitro Compounds; D011720:Pyrazoles; C082359:imidacloprid; C082360:fipronil