Hepatic resections for non-colorectal metastases: forty resections in 35 patients.
OBJECTIVE
Hepatic resection, though now an accepted practice for colorectal primary tumors, is poorly documented for non-colorectal metastases. However, the few series reported suggest that this approach may lead to a significant increase in survival.


METHODS
Study of 40 cases of resection in 35 patients with non-colorectal hepatic metastasis to define the role of hepatic resection between 1986 and 1997.


RESULTS
Resection was performed for 5 metastases of ovarian and fallopian tube carcinoma, 8 gastrointestinal tract adenocarcinomas, 8 endocrine tumors, 8 sarcomas and 6 miscellaneous metastases, involving 17 lobectomies, 3 trisegmentectomies, 5 lateral segmentectomies and 15 non-anatomical local resections. Survival at 1, 2 and 5 years was 54 +/- 8, 42 +/- 8 and 27 +/- 8%, respectively. Hepatic metastases of gastrointestinal tract adenocarcinomas were found to have the poorest prognosis (median time: 13 months), and genital tract adenocarcinomas the best (27 months).


CONCLUSIONS
Some carefully selected patients may benefit from liver resection for non-colorectal metastases.
Hamy
A P
AP
Department of Surgery, University Hospital, Nantes, France.
Paineau
J R
JR
Mirallie
E C
EC
Bizouarn
P
P
Visset
J P
JP
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D016016:Proportional Hazards Models; D012044:Regression Analysis; D016019:Survival Analysis; D016896:Treatment Outcome