title: Effects of material properties and geometry on electrocardiographic forward simulations.
abstract: This paper investigates the effect on torso potentials of changes in the material properties of the torso volume conductor and changes in the relative geometry of the heart and torso. The investigations are performed using a number of forward simulations with a high-order coupled finite element/boundary element torso model. This torso model contains descriptions of the epicardium, lungs, skeletal muscle (with a continuously varying fiber field) and subcutaneous fat. The number of nodes, elements and solution degrees-of-freedom used in the computational torso model are considerably smaller than previous torso models of similar complexity. The successful forward simulations in this paper hence demonstrate the use of the high-order coupled approach with realistic problems. The results of the torso simulations show that the torso inhomogeneities do affect the torso potentials but do not affect the distribution or pattern of the torso potentials. The inhomogeneities considered are found to have a varying, but important, effect on the torso potentials. The effect of the subcutaneous fat is found to be more important and the effect of the skeletal muscle is found to be less important than previous reports in the literature. The results also show that the relative geometry of the heart and torso is very important in determining the torso potential magnitudes and distributions.
authors.affiliation: Department of Engineering Science, University of Auckland, New Zealand.
authors.forename: C P
authors.initials: CP
authors.lastname: Bradley
authors.forename: A J
authors.initials: AJ
authors.lastname: Pullan
authors.forename: P J
authors.initials: PJ
authors.lastname: Hunter
mesh_terms: D000005:Abdomen / Q000033:anatomy & histology* / Q000502:physiology*; D000200:Action Potentials / Q000502:physiology; D016880:Anisotropy; D015982:Bias; D003198:Computer Simulation; D004594:Electrophysiology; D020342:Finite Element Analysis; D006329:Heart Conduction System / Q000502:physiology*; D006801:Humans; D016018:Least-Squares Analysis; D008279:Magnetic Resonance Imaging; D008297:Male; D008955:Models, Cardiovascular; D009716:Numerical Analysis, Computer-Assisted; D012399:Rotation; D012680:Sensitivity and Specificity; D013499:Surface Properties; D013909:Thorax / Q000033:anatomy & histology* / Q000502:physiology*