title: Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling.
authors.affiliation: Division of Experimental Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Medical School, Rochester, Minnesota, USA. liu.wanguo@mayo.edu
authors.forename: W
authors.initials: W
authors.lastname: Liu
authors.forename: X
authors.initials: X
authors.lastname: Dong
authors.forename: M
authors.initials: M
authors.lastname: Mai
authors.forename: R S
authors.initials: RS
authors.lastname: Seelan
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
authors.forename: K K
authors.initials: KK
authors.lastname: Krishnadath
authors.forename: K C
authors.initials: KC
authors.lastname: Halling
authors.forename: J M
authors.initials: JM
authors.lastname: Cunningham
authors.forename: L A
authors.initials: LA
authors.lastname: Boardman
authors.forename: C
authors.initials: C
authors.lastname: Qian
authors.forename: E
authors.initials: E
authors.lastname: Christensen
authors.forename: S S
authors.initials: SS
authors.lastname: Schmidt
authors.forename: P C
authors.initials: PC
authors.lastname: Roche
authors.forename: D I
authors.initials: DI
authors.lastname: Smith
authors.forename: S N
authors.initials: SN
authors.lastname: Thibodeau
mesh_terms: D060466:Axin Protein; D020137:Base Pair Mismatch / Q000235:genetics*; D002460:Cell Line; D015179:Colorectal Neoplasms / Q000235:genetics*; D003598:Cytoskeletal Proteins / Q000096:biosynthesis / Q000235:genetics* / Q000502:physiology*; D004252:DNA Mutational Analysis; D004260:DNA Repair / Q000235:genetics*; D017930:Genes, Reporter; D006801:Humans; D009154:Mutation; D015398:Signal Transduction; D051820:TCF Transcription Factors; D015534:Trans-Activators; D058118:Transcription Factor 7-Like 2 Protein; D014157:Transcription Factors / Q000502:physiology*; D014162:Transfection; D051176:beta Catenin
chemical_list: C491761:AXIN2 protein, human; D060466:Axin Protein; C495270:CTNNB1 protein, human; D003598:Cytoskeletal Proteins; D051820:TCF Transcription Factors; C544894:TCF7L2 protein, human; D015534:Trans-Activators; D058118:Transcription Factor 7-Like 2 Protein; D014157:Transcription Factors; D051176:beta Catenin