title: Preoperative simulation of outcomes using adaptive optics.
abstract: Measurements of the wavefront of light reflected from the retina of the human eye can be used to determine optical aberrations of the human eye for large pupils. An instrument based on the Hartmann-Shack principle was developed. The wavefront is refracted by a microlens array and detected by a CCD camera. In first clinical studies human volunteer eyes and preoperative and postoperative refractive surgical patient eyes have been examined. An adaptive optical closed loop system has been devised for preoperative simulation of refractive outcomes of aberration free refractive surgical procedures.
authors.affiliation: Kirchhoff Institute of Physics, University of Heidelberg, Germany.
authors.forename: J F
authors.initials: JF
authors.lastname: Bille
mesh_terms: D000221:Adaptation, Ocular; D003198:Computer Simulation; D003315:Cornea / Q000503:physiopathology* / Q000601:surgery; D019781:Corneal Topography; D006801:Humans; D054018:Lasers, Excimer; D055095:Optics and Photonics; D018903:Photorefractive Keratectomy; D011300:Preoperative Care; D012029:Refraction, Ocular; D012030:Refractive Errors / Q000503:physiopathology*; D054140:Refractive Surgical Procedures; D016896:Treatment Outcome; D014792:Visual Acuity