Effect of chronic gamma-irradiation and beta-carotene on lipid metabolism in presynaptic membranes in rat brain.
Lysophosphatidylcholine is involved in radiation-induced modulation of presynaptic membranes in rat brain. High sensitivity of the cortical integrative functions to chronic low-dose gamma-irradiation is demonstrated. beta-Carotene produced a protective effect during chronic irradiation.
Kolomiitseva
I K
IK
Laboratory of Radiation Biochemistry and Cell Regulation, Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region. kulagina@ibfk.nifhi.ac.ru
Potekhina
N I
NI
Semenova
T P
TP
Medvinskaya
N I
NI
Popov
V I
VI
Vakulova
L A
LA
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002540:Cerebral Cortex / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects / Q000648:ultrastructure; D005720:Gamma Rays; D008244:Lysophosphatidylcholines / Q000378:metabolism*; D008297:Male; D010812:Physical Stimulation; D051381:Rats; D017208:Rats, Wistar; D013570:Synaptic Membranes / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects / Q000648:ultrastructure; D013574:Synaptosomes / Q000737:chemistry / Q000378:metabolism / Q000648:ultrastructure; D019207:beta Carotene / Q000008:administration & dosage / Q000494:pharmacology*
D000975:Antioxidants; D008244:Lysophosphatidylcholines; D019207:beta Carotene