title: Child vaccination, part 1: routine vaccines.
abstract: Despite the success of the national childhood vaccination program in the United States in decreasing mortality due to vaccine-preventable diseases, vaccination rates remain suboptimal. Contributing factors include the failure to appreciate the hazards of vaccine-preventable diseases, concerns about adverse reactions associated with vaccine administration, and missed opportunities to administer vaccines. The 2 major types of indications for vaccinating children are age and presence of a medical condition that increases the risk of a vaccine-preventable disease. Hepatitis B virus (HBV) infection becomes chronic in 90% of those infected as infants, and 25% of those so infected will die of related chronic liver disease as adults. Routine infant vaccination against hepatitis B has been recommended since 1991. Approximately 69% of infants who develop pertussis require hospitalization. Acellular pertussis vaccines have been licensed for use in infancy. Starting in 2000, the all-inactivated poliovirus vaccine (IPV) schedule is recommended. IPV should eliminate vaccine-associated paralytic poliomyelitis. Pneumococcal conjugate vaccine was licensed in 2000 for routine use on a schedule of 2, 4, 6, and 12 to 15 months. The first dose of measles-mumps-rubella vaccine is now recommended at age 12 to 15 months, simultaneous with varicella vaccine administration.
authors.affiliation: Department of Family Medicine and Clinical Epidemiology, University of Pittsburgh School of Medicine, Pennsylvania 15261, USA. zimmer+@pitt.edu
authors.forename: R K
authors.initials: RK
authors.lastname: Zimmerman
authors.forename: I T
authors.initials: IT
authors.lastname: Burns
mesh_terms: D002648:Child; D002662:Child Health Services / Q000458:organization & administration; D002675:Child, Preschool; D006801:Humans; D017589:Immunization Programs; D007223:Infant; D007231:Infant, Newborn; D014481:United States; D014611:Vaccination / Q000592:standards / Q000706:statistics & numerical data; D014612:Vaccines / Q000009:adverse effects
chemical_list: D014612:Vaccines