title: Are antibiotics necessary in the treatment of locally infected ingrown toenails?
abstract: BACKGROUND
  A wide variety of generalists and specialists treat locally infected ingrown toenails, with perhaps the most common treatment regimen including resection of the nail border coupled with oral antibiotics.
  
  
  OBJECTIVE
  To determine whether oral antibiotic therapy is beneficial as an adjunct to the phenol chemical matrixectomy in the treatment of infected ingrown toenails.
  
  
  METHODS
  We prospectively enrolled healthy patients with infected ingrown toenails. Each patient was randomly assigned to 1 of 3 groups that received either 1 week of antibiotics and a chemical matrixectomy simultaneously (group 1), antibiotics for 1 week and then a matrixectomy (group 2), or a matrixectomy alone (group 3).
  
  
  METHODS
  Institutional ambulatory outpatient clinic.
  
  
  METHODS
  Fifty-four healthy patients with infected ingrown toenails were studied. Patients with immunocompromised states, peripheral vascular disease, or cellulitis proximal to the hallux interphalangeal joint were excluded. Groups were age matched for comparison.
  
  
  RESULTS
  Mean healing times for groups 1, 2, and 3 were 1.9, 2.3, and 2.0 weeks, respectively. Subjects receiving antibiotics and a simultaneous chemical matrixectomy (group 1) healed significantly sooner than those receiving a 1-week course of antibiotics followed by a matrixectomy (group 2). There was not a significant difference in healing time between those that received a chemical matrixectomy alone (group 3) and those that received a matrixectomy coupled with a course of oral antibiotics (group 1).
  
  
  CONCLUSIONS
  The use of oral antibiotics as an adjunctive therapy in treating ingrown toenails does not play a role in decreasing the healing time or postprocedure morbidity.
authors.affiliation: Ankle and Foot Clinic, 1114 Broadway St, Longview, WA 98665, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Reyzelman
authors.forename: K A
authors.initials: KA
authors.lastname: Trombello
authors.forename: D J
authors.initials: DJ
authors.lastname: Vayser
authors.forename: D G
authors.initials: DG
authors.lastname: Armstrong
authors.forename: L B
authors.initials: LB
authors.lastname: Harkless
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002425:Cautery / Q000379:methods; D002506:Cephalexin / Q000627:therapeutic use; D002648:Child; D005260:Female; D006214:Hallux; D006801:Humans; D008297:Male; D008875:Middle Aged; D009263:Nails, Ingrown / Q000150:complications / Q000628:therapy*; D011446:Prospective Studies; D012874:Skin Diseases, Infectious / Q000188:drug therapy* / Q000209:etiology; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D002506:Cephalexin