Utility of tissue culture for detection of Toxoplasma gondii in vitreous humor of patients diagnosed with toxoplasmic retinochoroiditis.
Laboratory recovery and confirmation of the etiologic agent in necrotizing retinochoroiditis are problematic. Tissue culture and intraocular antibody titers were compared as adjuncts to clinical diagnosis for toxoplasmic retinochoroiditis: the correlations were 91 and 67%, respectively. Isolation of Toxoplasma gondii may establish a definitive diagnosis in patients with toxoplasmic retinochoroiditis.
Miller
D
D
Ocular Microbiology Department, Bascom Palmer Eye Institute, Anne Bates Leach Eye Hospital, University of Miami School of Medicine, Miami, Florida 33136, USA. dmiller@bpei.med.miami.edu
Davis
J
J
Rosa
R
R
Diaz
M
M
Perez
E
E
D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D046508:Culture Techniques / Q000379:methods; D003937:Diagnosis, Differential; D006801:Humans; D015203:Reproducibility of Results; D013997:Time Factors; D014122:Toxoplasma / Q000254:growth & development / Q000276:immunology / Q000302:isolation & purification*; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis* / Q000276:immunology / Q000469:parasitology; D014822:Vitreous Body / Q000276:immunology / Q000469:parasitology*
D000913:Antibodies, Protozoan