title: [A case of subacute sclerosing panencephalitis showing various cerebral perfusion on 99mTc-ECD SPECT].
abstract: We reported serial neuroradiological findings of a 20-year-old male with subacute sclerosing panencephalitis, who deteriorated from Jabbour stage 2 to stage 4 rapidly in spite of oral administration of inosine pranobex. At the stage 2, brain magnetic resonance imaging (MRI), computed tomography (CT) and [99mTc]-L, L-ethyl cysteinate dimer (99mTc-ECD) single photon emission computed tomography(SPECT) findings were normal. As the disease progressed, brain MRI and CT revealed diffuse cerebral white matter lesions as well as cerebral atrophy. 99mTc-ECD SPECT showed serially various perfusion of cerebrum. These findings in 99mTc-ECD SPECT may reflect the acute inflammatory process and consequent destruction of brain tissue.
authors.affiliation: Department of Neurology, Toneyama National Hospital, Osaka.
authors.forename: T
authors.initials: T
authors.lastname: Saito
authors.forename: J
authors.initials: J
authors.lastname: Kang
mesh_terms: D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation; D003545:Cysteine / Q000031:analogs & derivatives*; D018450:Disease Progression; D006801:Humans; D008297:Male; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D013344:Subacute Sclerosing Panencephalitis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C059659:technetium Tc 99m bicisate; D003545:Cysteine