[Current approach to the treatment of acute bronchial asthma].
OBJECTIVE
To evaluate the results of nebulised berodual solution in comparison with intravenous euphylline in the treatment of acute bronchial asthma (BA).


METHODS
The trial entered 73 patients with an acute episode of BA: 22 treated with intravenous euphylline and 51 treated with nebulised berodual solution. Spirometry was conducted and peak expiratory flow rate, heart rate (HR), blood pressure were measured before and after the treatment.


RESULTS
The attack was arrested in all the patients who had inhaled nebulised berodual solution. No side effects were registered. Intravenous therapy of euphylline produced only partial bronchodilation in most of the patients and increased HR by 23.4%.


CONCLUSIONS
Berodual nebulised solution is clinically superior to intravenous euphylline in acute BA.
Bender
S B
SB
Vizel'
A A
AA
D000208:Acute Disease; D000280:Administration, Inhalation; D000328:Adult; D000336:Aerosols; D000628:Aminophylline / Q000008:administration & dosage*; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D001794:Blood Pressure / Q000187:drug effects; D016084:Bronchoconstriction / Q000187:drug effects; D001993:Bronchodilator Agents / Q000008:administration & dosage*; D004338:Drug Combinations; D005260:Female; D005280:Fenoterol / Q000008:administration & dosage*; D005541:Forced Expiratory Volume; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007275:Injections, Intravenous; D009241:Ipratropium / Q000008:administration & dosage*; D008297:Male; D009330:Nebulizers and Vaporizers
D000336:Aerosols; D001993:Bronchodilator Agents; D004338:Drug Combinations; C030809:fenoterol, ipratropium drug combination; D005280:Fenoterol; D000628:Aminophylline; D009241:Ipratropium