HRT to prevent cardiovascular disease. What studies show, how to advise patients.
How should you advise postmenopausal patients who are considering estrogen therapy? Do the potential cardiovascular benefits outweigh the risks? Does hormone therapy improve the cardiovascular risk profile in women with established coronary artery disease? In this article, Drs Wood and Cox help clarify the current clinical data for and against hormone replacement therapy for prevention of cardiovascular disease. In addition, they discuss current treatment recommendations and future directions in hormone therapy.
Wood
M J
MJ
Dalhousie University School of Medicine, Halifax, Nova Scotia.
Cox
J L
JL
D002318:Cardiovascular Diseases / Q000517:prevention & control*; D002319:Cardiovascular System / Q000187:drug effects; D002986:Clinical Trials as Topic; D015914:Estrogen Replacement Therapy; D004967:Estrogens / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008593:Menopause; D012307:Risk Factors
D004967:Estrogens; D008055:Lipids