Inhaled corticosteroid nonadherence and immediate avoidable medical events in older adults with chronic pulmonary ailments.
This study examined the association between nonadherence to inhaled corticosteroids and risk of an immediate avoidable medical event (emergency department visit and hospitalization) in elderly patients with chronic pulmonary ailments. The study comprised a cross-sectional analysis comparing patients with and without avoidable medical event occurrence in each year for adherence preceding the event, and a case-crossover analysis examining the same patient's adherence in years with and without events. The cross-sectional study showed risk odds reductions of nearly 20% in the partially adherent patient, and 40% in the adherent patient compared to the nonadherent patient, after controlling for potential group differences.
Balkrishnan
R
R
Department of Public Health Sciences, Asthma Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA. rbalkris@wfubmc.edu
Christensen
D B
DB
D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage* / Q000009:adverse effects; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D004636:Emergency Service, Hospital; D005500:Follow-Up Studies; D006279:Health Maintenance Organizations; D006760:Hospitalization; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000188:drug therapy*; D018570:Risk Assessment; D016312:Treatment Refusal
D000305:Adrenal Cortex Hormones