Duration of viraemia and faecal viral excretion in acute hepatitis E.
Data on duration of viral excretion and viraemia during hepatitis E virus (HEV) infection are limited. We tested serial stool and serum samples from 20 patients with acute hepatitis E for HEV RNA. Faecal excretion and viraemia in these patients were found to be short lived. In 19 patients, all samples obtained after biochemical resolution of hepatitis tested negative; in the remaining patient, HEV RNA was detected in the serum samples but not in stool after biochemical resolution. Long-term persistence of HEV in body fluids of infected individuals seems to be an unlikely reservoir for transmission of HEV.
Aggarwal
R
R
Kini
D
D
Sofat
S
S
Naik
S R
SR
Krawczynski
K
K
D000208:Acute Disease; D000328:Adult; D005243:Feces / Q000821:virology*; D016751:Hepatitis E / Q000097:blood / Q000821:virology*; D016752:Hepatitis E virus / Q000235:genetics; D006801:Humans; D012367:RNA, Viral / Q000097:blood; D013997:Time Factors; D014766:Viremia / Q000821:virology*
D012367:RNA, Viral