[Multiple cerebral infarcts associated with livedo secondary to anti-cancer therapy with interleukin 2 and interferon alpha].
Anticancer drugs rarely cause strokes. We report the case of a woman treated for a kidney cancer by IL2 and IFN alpha, having developed multiple strokes associated with a livedo. The responsibility of IL2 and IFN alpha seemed likely. The association with a transitory livedo suggested that the pathological process might be a cerebral angiopathy with arterial vasospasms.
Drapier
S
S
Clinique Neurologique, CHU Rennes.
Kassiotis
P
P
Mourtada
I
I
Pinel
J F
JF
Edan
G
G
D000230:Adenocarcinoma / Q000188:drug therapy; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001921:Brain / Q000473:pathology; D002544:Cerebral Infarction / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects*; D007376:Interleukin-2 / Q000009:adverse effects*; D007680:Kidney Neoplasms / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018860:Sneddon Syndrome / Q000139:chemically induced* / Q000150:complications
D000970:Antineoplastic Agents; D016898:Interferon-alpha; D007376:Interleukin-2