Hepatitis G virus (HGV) infection in voluntary and commercial blood donors in India.
The prevalence of hepatitis G virus (HGV) has been determined in commercial as well as voluntary blood donors from India by detecting viral RNA genome using reverse transcription polymerase chain reaction (RT-PCR) assay. 45 professional blood donors from private blood banks and 50 healthy controls who opted for voluntary blood donation were recruited for the study. Both the groups were also screened serologically for HBV and HCV infection. The prevalence of HGV in the general population in India was found to be 4% but significantly a higher frequency (46.6%; p<0.001) of HGV was observed in commercial blood donors.
Kar
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P
Department of Medicine, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India. pkar@del6.vsnl.net.in
Bedi
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P
Berry
N
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Chakravorty
A
A
Gupta
R K
RK
Saha
R
R
Das
B C
BC
D001782:Blood Donors / Q000706:statistics & numerical data*; D017931:DNA Primers / Q000737:chemistry; D004279:DNA, Viral / Q000737:chemistry; D004587:Electrophoresis, Agar Gel; D004797:Enzyme-Linked Immunosorbent Assay; D018067:Flaviviridae / Q000235:genetics / Q000302:isolation & purification*; D016174:Hepacivirus / Q000302:isolation & purification; D006509:Hepatitis B / Q000097:blood; D006515:Hepatitis B virus / Q000302:isolation & purification; D006526:Hepatitis C / Q000097:blood; D006525:Hepatitis, Viral, Human / Q000097:blood* / Q000453:epidemiology; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D012367:RNA, Viral / Q000737:chemistry / Q000302:isolation & purification; D020133:Reverse Transcriptase Polymerase Chain Reaction
D017931:DNA Primers; D004279:DNA, Viral; D012367:RNA, Viral