[Gastric acid secretion in gastroesophageal reflex disease].
The gastric acid secretion was evaluated by serum pepsinogen I/II ratio and serum Helicobacter pylori IgG antibody titer in gastroesophageal reflux disease(GERD) patient. GERD patients was 81 patients. Los-Angeles classification (LA)O, so called endoscopy negative reflux disease, was 6 patients, and LA-O-B patients was 68 patients. Helicobacter pylori infection ratio in GERD patients was 50.6%(41/81 patients). Pepsinogen I/II ratio in Helicobacter pylori positive GERD patients was no significant different from Helicobacter pylori negative GERD patients. We concluded that the gastric acid secretion in GERD patients was normal secretion.
Koyama
S
S
Second Department of Internal Medicine, Shiga University of Medical Science.
Bamba
T
T
D005744:Gastric Acid / Q000378:metabolism*; D005764:Gastroesophageal Reflux / Q000503:physiopathology*; D016481:Helicobacter Infections / Q000503:physiopathology; D016480:Helicobacter pylori; D006801:Humans