[Correction by common sea buckthorn bark and sprout extracts of hormonal and metabolic disturbances during stress in rats].
Long-term administration of the common sea buckthorn bark and sprout extract improves the hormonal-metabolic organism status in rats disturbed by a stress factor (immobilization). The drug administration led to normalization of the altered functional activity indices of the neuro-endocrine system (disturbed adrenocorticotropin, 11-deoxycortisol, insulin, urea, and glucose levels) by affecting the production of glucocorticoids and increasing the hypothalamus sensitivity with respect to regulatory signals.
Krylova
S G
SG
Institute of Pharmacology, Tomsk Scientific Center, Siberian Division, Russian Academy of Medical Sciences, Russia.
Konovalova
O N
ON
Zueva
E P
EP
D000324:Adrenocorticotropic Hormone / Q000378:metabolism / Q000494:pharmacology; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003350:Cortodoxone / Q000097:blood; D003907:Dexamethasone / Q000494:pharmacology; D006706:Homeostasis; D006728:Hormones / Q000378:metabolism*; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects; D007328:Insulin / Q000097:blood; D010913:Pituitary-Adrenal System / Q000187:drug effects; D010936:Plant Extracts / Q000627:therapeutic use*; D018547:Plant Stems / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D013312:Stress, Physiological / Q000188:drug therapy* / Q000378:metabolism; D014508:Urea / Q000097:blood
D001786:Blood Glucose; D006728:Hormones; D007328:Insulin; D010936:Plant Extracts; D003907:Dexamethasone; D014508:Urea; D000324:Adrenocorticotropic Hormone; D003350:Cortodoxone