[The genetic sequelae of irradiation in mammals (a review of the literature)].
The problem of hereditary effects of mammal exposure to ionizing radiation has a 95-year history but to date, no simple final solution has been available. Many papers on this problem specify the dependence of the hereditary effects on dose rate, regime, physical nature of radiation exposure, type, line and age of mammals that were studied. Over many years it was studied mainly as an aspect of hereditary radiation effects in progeny of one irradiated and the second non-irradiated parents. Recently due to the large-scale expansion of ionizing irradiation, it has turned out urgent to study hereditary radiation effects in progeny of both irradiated parents. However, the original studies on this problem are not numerous, and in the summarized articles, the problem practically had no specified presentation.
Nefedov
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Medical Radiological Research Centre, Russian Academy of Medical Science, Obninsk, Russia. mrrc@obninsk.ru
Nefedova
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Palyga
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GF
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D005260:Female; D008297:Male; D008322:Mammals / Q000235:genetics*; D008967:Molecular Biology / Q000528:radiation effects; D010063:Ovum / Q000528:radiation effects; D011830:Radiation Effects; D011836:Radiation Tolerance; D013094:Spermatozoa / Q000528:radiation effects