title: Anterior commissure carcinoma: I-histopathologic study.
abstract: OBJECTIVE
  To study the behavior of anterior commissure carcinoma regarding its tendency for cartilage invasion.
  
  
  METHODS
  Histopathological examination of the region of the anterior commissure (AC) was done with whole organ section in 30 randomly selected specimens. Serial sections were prepared and examined histopathologically for evidence of microscopic cartilage invasion in the region of the AC.
  
  
  RESULTS
  Microscopic involvement of the thyroid cartilage was detected in the 30 sections studied.
  
  
  CONCLUSIONS
  Whether recurrence was de novo or initiated by residual malignant cells, it is mandatory to excise the anterior portion of the thyroid cartilage with the tumor-bearing mucosa.
authors.affiliation: Otorhinolarygology Department, Kasr El-Aini School of Medicine, Cairo University, Egypt.
authors.forename: M
authors.initials: M
authors.lastname: Rifai
authors.forename: H
authors.initials: H
authors.lastname: Khattab
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005931:Glottis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007820:Laryngeal Mucosa / Q000473:pathology; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012008:Recurrence; D013957:Thyroid Cartilage / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology