Searching for a cord blood unit for transplantation based on the unit's cell count.
Although recipients of unrelated cord blood can tolerate a greater degree of HLA-disparity than recipients of unrelated bone marrow, cell dose is also important. After an unsuccessful search for a bone marrow donor, and after initially dismissing a cord blood search because the patient was 52 kg, we used a different search strategy to identify an unrelated cord blood unit. This led to successful engraftment and transplantation for a patient with no bone marrow donor.
Bleakley
M
M
Oncology Unit, The New Children's Hospital, Westmead, Sydney, Australia.
Shaw
P J
PJ
D000293:Adolescent; D002452:Cell Count; D005312:Fetal Blood / Q000166:cytology*; D006085:Graft Survival; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy; D012074:Remission Induction