Pyoderma gangrenosum and myelodysplastic syndrome.
Pyoderma gangrenosum (PG) is a painful, often rapidly progressive, ulcerating skin disorder frequently associated with systemic diseases. We report the case of a patient with PG and an anemia. A bone marrow biopsy showed changes consistent with one of the myelodysplastic syndromes, refractory anemia with ringed sideroblasts. Patients with PG and anemia should have bone marrow biopsy if no cause of anemia is readily apparent.
Litvak
D
D
Department of Medicine, Yale University School of Medicine, New Haven, Conn, USA.
Kirsner
R S
RS
Pakdaman
N N
NN
Federman
D G
DG
D000753:Anemia, Refractory / Q000209:etiology; D000756:Anemia, Sideroblastic / Q000209:etiology; D001856:Bone Marrow Examination; D005938:Glucocorticoids / Q000627:therapeutic use; D006400:Hematocrit; D006801:Humans; D007868:Leg Dermatoses / Q000188:drug therapy / Q000209:etiology*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications*; D009504:Neutrophils / Q000473:pathology; D010976:Platelet Count; D011241:Prednisone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000188:drug therapy / Q000209:etiology*
D005938:Glucocorticoids; D011241:Prednisone