title: Spatial resolution in echo planar imaging: shifting the acquisition window in k-space.
abstract: Single-shot echo planar imaging (EPI) is one of the most suitable techniques for very fast image acquisition, especially in functional MRI. In standard EPI schemes the k-space center is sampled in the middle of the acquisition train. This leads to longer echo times for higher spatial resolutions, as well as reduced signal intensity and signal-to-noise ratio. Therefore, echo shifting to lower echo times is often used. After a brief overview on the theoretical background of various point-spread-functions (PSF) computational simulations are presented, which quantify the modulation amplitude of a binary test object sampled with either standard, zero-filled or shifted k-space acquisition. The results suggest that echo-shifting with zero-filling is not advantageous, not even with small matrix sizes, and that echo-shifting with additional acquisition of outer k-space lines decreases the modulation amplitude only slightly. Simulations were also performed on noise-corrupted test objects, indicating that the use of the echo-shifted scheme causes resolution loss of up to 30% compared to the standard scheme for a 128 by 128 pixel matrix at a noise level of 20%. Finally, in vivo experiments using different echo shifts are presented and the characteristics of signal and noise with varying TE are quantified.
authors.affiliation: Arbeitsgruppe NMR, Institut für Medizinische Physik, Universität Wien, A-1090, Vienna, Austria.
authors.forename: C
authors.initials: C
authors.lastname: Windischberger
authors.forename: E
authors.initials: E
authors.lastname: Moser
mesh_terms: D017352:Echo-Planar Imaging / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008962:Models, Theoretical; D019047:Phantoms, Imaging; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted