title: Stress-induced expression of co-localized neuropeptides in hypothalamic and amygdaloid neurons.
abstract: This short review summarizes the effect of various stressful stimuli on the expression of neuropeptides which co-localize in corticotrophin releasing hormone (CRH)-synthesizing neurons in the hypothalamic paraventricular nucleus, as well as in oxytocin and vasopressin neurons in the supraoptic nucleus. Stress-induced changes failed to act on CRH neurons in the central amygdaloid nucleus but formalin-evoked pain enhanced galanin mRNA expression in the medial subdivision of this nucleus. Changes in the expression of enkephalin, galanin, dynorphin and cholecystokinin mRNA in response to restraint and formalin-induced pain are documented in hypothalamic and amygdaloid nuclei by in situ hybridization histochemical technique.
authors.affiliation: Laboratory of Neuromorphology, Semmelweis University Budapest, Tüzoltó u. 58, H-1094, Budapest, Hungary. palkovits@ana.sote.hu
authors.forename: M
authors.initials: M
authors.lastname: Palkovits
mesh_terms: D000679:Amygdala / Q000166:cytology / Q000378:metabolism*; D000818:Animals; D006801:Humans; D007031:Hypothalamus / Q000166:cytology / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D009479:Neuropeptides / Q000096:biosynthesis*; D013315:Stress, Psychological / Q000378:metabolism*
chemical_list: D009479:Neuropeptides