On the spectral periodicity of transient-evoked otoacoustic emissions from normal and damaged cochleas.
The spectral quasi-periodicity of transient-evoked otoacoustic emissions (TEOAE) is well acknowledged since Zwicker described a preferred spacing of 0.4 bark between consecutive peaks in the spectrum of otoacoustic emissions from normal ears. While there is scarce evidence of any anatomical reason for this regularity, several functional models of the cochlea have predicted that the structure of emission spectra reflects important characteristics of cochlear filters. In an attempt to check such predictions, the average regularity of TEOAE spectra was studied in three groups of human subjects, normally hearing adults, healthy neonates, and adults suffering from noise-induced hearing loss. Significant differences in emission periodicities were found. Around 1 kHz, the preferred spacing was close to 130 Hz in normally hearing adult ears and neonates. In contrast, no clear periodicity was found in the group of damaged ears, even though they had clinically normal pure-tone audiometry below 2 kHz. Around 4 kHz, the preferred spacing was close to 240 Hz in normal adults and neonates, whereas TEOAEs were absent in many impaired ears. A phenomenological model assuming that TEOAEs stem from the responses of a slightly disarrayed bank of highly tuned filters predicts that the filter width would be the same in healthy young adults and neonates. In contrast, ears suffering from high-frequency hearing loss could exhibit early damaged filters. The proposed method might provide an objective assessment of parameters otherwise difficult to evaluate, especially in neonatal cochleas.
Avan
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Laboratory of Sensory Biophysics, School of Medicine, Clermont-Ferrand, France. paul.avan@u-clermont1.fr
Wit
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Guitton
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Mom
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Bonfils
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D000328:Adult; D001301:Audiometry, Pure-Tone / Q000379:methods; D003051:Cochlea / Q000503:physiopathology*; D006309:Hearing / Q000502:physiology; D006317:Hearing Loss, Noise-Induced / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008954:Models, Biological; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*; D010507:Periodicity