Spectroscopic study of 1,2-indandione.
This paper describes the spectroscopic study of the new fingerprint reagent, 1,2-indandione, using nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry (MS). When 1,2-indandione is dissolved in methanol, NMR and MS show formation of a hemiketal similar to that proposed for DFO when it is dissolved in methanol. In contrast to DFO where reactivity with amino acids appears to be enhanced by hemiketal formation with alcohol solvents, the reactivity of 1,2-indandione towards amino acids is diminished by hemiketal formation. Alcohols should be avoided in 1,2-indandione formulations.
Wilkinson
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Forensic Identification Research Service, Royal Canadian Mounted Police, NPS Building, Room 503, 1200 Vanier Parkway, Ottawa, Ontario, Canada K1A OR2.
D000438:Alcohols; D001372:Aza Compounds; D002626:Chemistry, Pharmaceutical; D003878:Dermatoglyphics; D006801:Humans; D007189:Indans / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D000432:Methanol; D008970:Molecular Weight; D012997:Solvents
C416542:1,2-indandione; C406982:1,8-diazafluoren-one; D000438:Alcohols; D001372:Aza Compounds; D007189:Indans; D012997:Solvents; D000432:Methanol