Estimating the dose variation in a volume of interest with explicit consideration of patient geometric variation.
A method to measure the effects of internal organ motion and deformation and patient setup error on cumulative dose variation in a volume of interest is proposed. The method uses multiple CT scans and electronic portal images of a single patient to numerically simulate dose-volume effects over the entire course of the patient's external beam treatment. The results are expressed in the form of a novel dose-volume histogram, called an expected dose-volume histogram (EDVH).
Lockman
D M
DM
William Beaumont Hospital, Department of Radiation Oncology, Royal Oak, Michigan 48073-6769, USA. dlockman@beaumont.edu
Yan
D
D
Wong
J
J
D006801:Humans; D008962:Models, Theoretical; D009068:Movement; D011874:Radiometry / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted; D015203:Reproducibility of Results; D012984:Software