Sentinel node and radioguided surgery in breast cancer of limited size. Preliminary experience at ASL 1, Massa e Carrara.
The aim of this study was to evaluate the effectiveness of sentinel node (SN) biopsy in breast cancer. Twenty-five female patients classified as T1N0 according to the TNM system of the UICC were evaluated with this procedure from April to October 1999. The day before surgery a subdermal injection of 99mTc-nanocoll within the tissue overlying the neoplastic lesion and subsequent lymphoscintigraphy were performed. In all patients the SN was detected with a radioguided probe during scintigraphy and surgery. Histological examination of the SN for detection of metastases was positive in four patients who subsequently underwent axillary dissection. In the remaining patients with normal SNs no axillary dissection was performed. The preliminary results confirm the validity of the sentinel node procedure.
Fialdini
G
G
Department of Oncology ASL 1 Massa e Carrara, Study Group on Radioguided Surgery, Italy.
Troiani
R
R
Manfredini
G
G
Bertolaccini
P
P
Bonini
R
R
Spinelli
I
I
Lambruschi
G
G
Piacentini
G
G
Pietrini
F
F
Gentili
M
M
Barbieri
L
L
Maneschi
A
A
Sicari
A
A
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008875:Middle Aged; D009367:Neoplasm Staging; D011877:Radionuclide Imaging; D016634:Radiosurgery; D015203:Reproducibility of Results; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*