title: Lignans from Mosla scabra.
abstract: Two new cyclobutane-type lignans, named moslolignans A and B, together with two known ones, andamanicin and magnosalin, were isolated from the whole plant of Mosla scabra. Their structures were established as 1beta*,2beta*,3alpha*,4alpha*-1,2-dimethyl-3-(3- methoxy-4,5-methylene-dioxyphenyl)-4-(2,4,5-trimethoxyphenyl)-cycl obutane and 1beta*,2beta*,3alpha*,4alpha*-1,2-dimethyl-3-(2, 5-dimethoxy-3,4-methylenedioxyphenyl)-4-(2,4,5-trimethoxyphenyl)-cyclobu tane by spectroscopic methods. This is the first report of naturally-occurring cyclobutane-type lignans with asymmetrical substitutions.
authors.affiliation: Institut de Pharmacognosie et Phytochimie, Université de Lausanne, Lausanne-Dorigny, Switzerland.
authors.forename: Q
authors.initials: Q
authors.lastname: Wang
authors.forename: C
authors.initials: C
authors.lastname: Terreaux
authors.forename: A
authors.initials: A
authors.lastname: Marston
authors.forename: R X
authors.initials: RX
authors.lastname: Tan
authors.forename: K
authors.initials: K
authors.lastname: Hostettmann
mesh_terms: D000475:Alkenes / Q000302:isolation & purification*; D003503:Cyclobutanes / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000475:Alkenes; D003503:Cyclobutanes