Total synthesis of (-)-ascochlorin via a cyclobutenone-based benzannulation strategy.
The application of a convergent benzannulation strategy in an efficient synthesis of (-)-ascochlorin is described.
Dudley
G B
GB
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Takaki
K S
KS
Cha
D D
DD
Danheiser
R L
RL
D000475:Alkenes / Q000138:chemical synthesis*; D003503:Cyclobutanes / Q000737:chemistry*; D010636:Phenols / Q000138:chemical synthesis*; D013237:Stereoisomerism
D000475:Alkenes; D003503:Cyclobutanes; D010636:Phenols; C415745:ascochlorin