The role of immune responses in bone loss during periodontal disease.
A network of cytokines and other soluble mediators unites the immune system and bone; bacterial infections induce immune responses which may perturb this network. Periodontal diseases are Gram-negative infections resulting in bone loss in the jaw. Evidence is presented that immune responses to these infections produces net resorption of bone.
Baker
P J
PJ
Biology Department, Bates College, Lewistown, Maine 04240, USA.
D016301:Alveolar Bone Loss / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D016723:Bone Remodeling; D016207:Cytokines / Q000378:metabolism; D006090:Gram-Negative Bacteria / Q000276:immunology / Q000378:metabolism; D016905:Gram-Negative Bacterial Infections / Q000150:complications / Q000276:immunology* / Q000473:pathology; D006801:Humans
D016207:Cytokines