Remote discharges in the posterior language area during basal temporal stimulation.
A 23-year-old woman with refractory complex partial seizures underwent implantation of subdural grid electrodes over the left hemisphere to map epileptic foci and language function. Aphasic symptoms occurred during stimulation of the basal temporal area, which were always associated with intrastimulus remote discharges (ISRDs) in the classical posterior language area. No sequential language deficits occurred after anterior temporal lobectomy including the basal temporal area. These results suggest a close functional relationship between the basal temporal area and posterior language area in patients with temporal lobe epilepsy. ISRDs may explain the paradoxical observation that resection of the basal temporal language area results in no language deficits.
Ishitobi
M
M
Department of Pediatrics, Tohoku University School of Medicine, Sendai, Japan.
Nakasato
N
N
Suzuki
K
K
Nagamatsu
K
K
Shamoto
H
H
Yoshimoto
T
T
D000328:Adult; D001037:Aphasia / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D001931:Brain Mapping / Q000379:methods; D004558:Electric Stimulation / Q000009:adverse effects*; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D009434:Neural Pathways / Q000033:anatomy & histology / Q000502:physiology*; D011859:Radiography; D011930:Reaction Time / Q000502:physiology; D012886:Skull / Q000000981:diagnostic imaging; D013060:Speech / Q000502:physiology*; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000502:physiology*