Management of nail psoriasis.
Nail psoriasis is often difficult to cure, but may respond to a range of different approaches used alone or together. As with treatment of psoriasis affecting skin, relapse is common and therapies may need to be maintained or repeated. The exact benefits of many of these treatments are not well documented in the literature. Basic nail care is important and topical therapies represent the main modality of treatment for the majority of cases. In severe nail disease, where there is a hypertrophic element, injection therapy with triamcinolone may be helpful. PUVA and other forms of radiation may be of benefit, but as with systemic therapy, they are usually useful in the context of treatment of psoriasis elsewhere on the body.
de Berker
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Bristol Dermatology Centre, Bristol Royal Infirmary, UK. deberker@nails.u-net.com
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D005938:Glucocorticoids; D006801:Humans; D007642:Keratosis / Q000628:therapy; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D009260:Nail Diseases / Q000601:surgery / Q000628:therapy*; D011565:Psoriasis / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D014222:Triamcinolone Acetonide / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D003879:Dermatologic Agents; D005938:Glucocorticoids; D016572:Cyclosporine; D014222:Triamcinolone Acetonide; D005472:Fluorouracil; D008727:Methotrexate