Resistance of mice exposed to whole-body irradiation to transplanted hemopoietic cells modified with RNA preparations.
The resistance of irradiated mice to bone marrow grafts treated with RNA from the liver of syngenic, allogenic, or xenogenic (rat) species was studied. Syngenic recipients developed resistance to grafts treated with allogenic RNA. The resistance to allografts increased after treatment with xenogenic RNA, whereas treatment of allo- and xenografts with syngenic RNA facilitated their take.
Nikolin
V P
VP
Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk.
Il'inskaya
S I
SI
Popova
N A
NA
Karakin
E I
EI
D000818:Animals; D001854:Bone Marrow Cells / Q000187:drug effects* / Q000378:metabolism; D016026:Bone Marrow Transplantation; D006085:Graft Survival; D006087:Graft vs Host Reaction; D008297:Male; D051379:Mice; D008805:Mice, Inbred A; D008807:Mice, Inbred BALB C; D008815:Mice, Inbred Strains; D012313:RNA / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D014183:Transplantation, Heterologous; D014184:Transplantation, Homologous; D014916:Whole-Body Irradiation
D012313:RNA