title: [Shuddering attacks in four children].
abstract: Shuddering attacks (SA), an uncommon benign disorder occurring during infancy or early childhood, should be distinguished from epileptic seizures. The attacks are shivering movements occurring daily for several seconds without impairment of consciousness. SA are regarded as an early premature manifestation of essential tremor (ET), and the provoking mechanism is the same between them. There are case reports of SA, but none from Japan. We studied the pathophysiology of SA in four children aged between 8 and 14 months using a video-EEG monitoring system. In one patient, the shuddering movements, as indicated by contaminating electromyogram during electroencephalography, was almost as frequent as that of ET. SA decreased in frequency or disappeared in all our patients. One of them showed immature brain development on MRI and had relatives with epilepsy. Another showed flattened sella turcica. Although previous reports suggest that SAs are benign and require no investigation, children with SA could have borderline problems related to the development of the nervous system.
authors.affiliation: Department of Pediatrics, Epilepsy Center, Nishi-Niigata Central National Hospital.
authors.forename: O
authors.initials: O
authors.lastname: Kanazawa
authors.forename: S
authors.initials: S
authors.lastname: Shirane
authors.forename: S
authors.initials: S
authors.lastname: Hayakawa
mesh_terms: D001921:Brain / Q000254:growth & development / Q000473:pathology; D003937:Diagnosis, Differential; D004569:Electroencephalography; D004827:Epilepsy; D020329:Essential Tremor / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D011379:Prognosis; D014741:Video Recording