[An assessment of the degree of chromophore photo damage to the heme and globin components in UV-irradiated molecules and electrophoretic fractions of human carboxyhemoglobin].
The contribution of hem and globin components of electrophoretic fractions of UV-irradiated human carboxyhemoglobin to photodestruction of the protein was studied. The changes observed are the result of summation of some processes unequal in intensity and direction that take place in microheterogeneous media of photomodified protein. Photosensitivity of hemoproteid in electrophoretic fraction depends on apoprotein condition, whereas the hem photoresistance cannot be the evidence of the photostability of the whole molecule.
Putintseva
O V
OV
Voronezh State University, Russia. bsbf188@main.vsu.ru
Artiukhov
V G
VG
Kalaeva
E A
EA
D001797:Blood Protein Electrophoresis / Q000379:methods / Q000706:statistics & numerical data; D002263:Carboxyhemoglobin / Q000032:analysis / Q000528:radiation effects*; D003116:Color; D004307:Dose-Response Relationship, Radiation; D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods / Q000706:statistics & numerical data; D005914:Globins / Q000032:analysis / Q000528:radiation effects*; D006418:Heme / Q000032:analysis / Q000528:radiation effects*; D006801:Humans; D011836:Radiation Tolerance; D012996:Solutions; D014466:Ultraviolet Rays
D012996:Solutions; D006418:Heme; D005914:Globins; D002263:Carboxyhemoglobin