The pathogenetic mechanism of myeloid malignancies associated with deletions of the long arm of chromosome 20 can not be explained by a "one hit" model. An acute myeloid leukemia patient who developed with 20q- clone during complete remission for 9 years.
Matsuda
A
A
Jinnai
I
I
Yagasaki
F
F
Ito
Y
Y
Ito
K
K
Kusumoto
S
S
Murohashi
I
I
Bessho
M
M
Hirashima
K
K
D002890:Chromosomes, Human, Pair 20; D017353:Gene Deletion; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D012074:Remission Induction