Chemotherapy for intramedullary spinal cord tumors.
Intramedullary tumors are rare, accounting for only about 4% of all CNS neoplasms. Although surgery represents the most effective treatment, recurrence may occur. As a large proportion of intramedullary malignancies occur in children, who are more sensitive to the deleterious effects of irradiation, chemotherapy assumes an important role. This article describes the most common intramedullary tumors and the role of chemotherapy.
Balmaceda
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Department of Neurology, Columbia University, New York, USA. cb116@columbia.edu
D000328:Adult; D001254:Astrocytoma / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D002648:Child; D004806:Ependymoma / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D015316:Genetic Therapy; D018237:Germinoma / Q000188:drug therapy*; D006801:Humans; D018242:Neuroectodermal Tumors, Primitive / Q000628:therapy; D011379:Prognosis; D013120:Spinal Cord Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery