title: Allele NAT2*5 determines resistance to bronchial asthma in children.
abstract: NAT2*5 allele was found in 54.8% healthy children and 35.9% children with bronchial asthma, i.e. the risk of bronchial asthma was considerably lower in individuals carrying NAT2*5 allele. NAT2*5 allele manifests itself in both homo- and heterozygous states.
authors.affiliation: Institute of Molecular Biology and Biophysics, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk. imbb@cyber.ma.nsc.ru
authors.forename: S I
authors.initials: SI
authors.lastname: Makarova
authors.forename: V A
authors.initials: VA
authors.lastname: Vavilin
authors.forename: V V
authors.initials: VV
authors.lastname: Lyakhovich
authors.forename: S M
authors.initials: SM
authors.lastname: Gavalov
mesh_terms: D000293:Adolescent; D001191:Arylamine N-Acetyltransferase / Q000235:genetics*; D001249:Asthma / Q000209:etiology / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D005260:Female; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D008297:Male; D009154:Mutation / Q000235:genetics; D016017:Odds Ratio; D011110:Polymorphism, Genetic; D014028:Tobacco Smoke Pollution
chemical_list: D014028:Tobacco Smoke Pollution; D001191:Arylamine N-Acetyltransferase; C478900:NAT2 protein, human