title: Immunization. Update: search for an AIDS vaccine.
abstract: Identifying a successful HIV preventive vaccine is among the highest research priorities of the US NIH. While therapies for HIV have brought hope to those who are already HIV-infected, stopping the worldwide epidemic will require safe, effective HIV vaccines. Here, we describe scientific and other obstacles to attaining that goal and provide a brief synopsis of clinical trial results, recent preclinical results, and future priorities.
authors.affiliation: Vaccine and Prevention Research Program, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Md., USA.
authors.forename: S
authors.initials: S
authors.lastname: Bende
authors.forename: M I
authors.initials: MI
authors.lastname: Johnston
mesh_terms: D016915:AIDS Vaccines / Q000276:immunology*; D000818:Animals; D023241:Antiretroviral Therapy, Highly Active; D002986:Clinical Trials as Topic; D015658:HIV Infections / Q000276:immunology / Q000517:prevention & control* / Q000628:therapy; D006801:Humans; D018928:Immunity, Mucosal; D007114:Immunization; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D019444:Vaccines, DNA / Q000276:immunology
chemical_list: D016915:AIDS Vaccines; D019444:Vaccines, DNA