[Oncovirus-induced permanent genetic instability in Drosophila melanogaster].
Mutant alleles of a system of genetic instability induced by oncoviral DNAs were shown to demonstrate an unstable manifestation 500 generations after their emergence. A cytogenetic analysis of oncovirus-induced unstable lines has revealed numerous chromosome rearrangements. For the Lobe alleles of this system, a specific chromosome rearrangement, Df(2L) = 35C-36B, was found on the left arm of chromosome 2. We used recessive lethal mutations involving DNA rearrangements in a successful construction of cross systems for "explosive" instability.
Mit'
N V
NV
Department of Genetics and Molecular Biology, Al-Farabi State University Kazakhstan, Almaty.
Dzhansugurova
L B
LB
Bersimbaev
R I
RI
D000483:Alleles; D000818:Animals; D004279:DNA, Viral; D004331:Drosophila melanogaster / Q000235:genetics* / Q000821:virology; D009154:Mutation; D012190:Retroviridae / Q000235:genetics / Q000502:physiology*
D004279:DNA, Viral