title: Isolation and characterization of adenovirus 5 from the brain of an infant with fatal cerebral edema.
abstract: This report describes a fatal case of cerebral edema caused by adenovirus in a previously healthy 18-month-old infant who developed skin rash, pulmonary congestion, and fever and who died 6 days later. Adenovirus hexon gene sequences were detected in brain tissue and brain tissue cultures. The virus was typed as adenovirus 5.
authors.affiliation: Virus Isolation and Reference Service Laboratory, New York State Health Department, Slingerlands, NY 12159, USA.
authors.forename: N K
authors.initials: NK
authors.lastname: Chatterjee
authors.forename: W A
authors.initials: WA
authors.lastname: Samsonoff
authors.forename: N
authors.initials: N
authors.lastname: Balasubramaniam
authors.forename: K
authors.initials: K
authors.lastname: Rush-Wilson
authors.forename: W
authors.initials: W
authors.lastname: Spargo
authors.forename: T M
authors.initials: TM
authors.lastname: Church
mesh_terms: D000258:Adenovirus Infections, Human / Q000150:complications / Q000821:virology*; D000260:Adenoviruses, Human / Q000235:genetics / Q000302:isolation & purification* / Q000648:ultrastructure; D001483:Base Sequence; D001921:Brain / Q000648:ultrastructure / Q000821:virology*; D001929:Brain Edema / Q000150:complications / Q000473:pathology*; D004279:DNA, Viral / Q000235:genetics; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012689:Sequence Homology, Nucleic Acid; D014407:Tumor Cells, Cultured
chemical_list: D004279:DNA, Viral