title: [Anal fissure--a new therapy concept].
abstract: The anal fissure is one of the most frequent causes for anal pain. Conservative treatment usually consists of laxatives, local anesthetics and nitroglycerin cream. These therapies have a high recurrency rate. Surgical interventions, i.e. manual dilatation and sphincterotomy are fraught with the danger of fecal incontinence. The completely reversible effect of botulinum toxin injection opens new possibilities in the treatment of anal fissures. Its use is discussed as part of a 3-stage therapeutic regimen.
authors.affiliation: Klinik für Viszeralchirurgie, Universitätsspital Zürich. fhetzer@dplanet.ch
authors.forename: F H
authors.initials: FH
authors.lastname: Hetzer
authors.forename: M
authors.initials: M
authors.lastname: Baumann
authors.forename: M
authors.initials: M
authors.lastname: Röthlin
mesh_terms: D000287:Administration, Topical; D001003:Anal Canal / Q000187:drug effects / Q000601:surgery; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage; D005401:Fissure in Ano / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007273:Injections, Intramuscular; D005996:Nitroglycerin / Q000008:administration & dosage
chemical_list: D019274:Botulinum Toxins, Type A; D005996:Nitroglycerin