title: An unusual case of malignant hyperthermia during desflurane anesthesia in an African-American patient.
abstract: Malignant hyperthermia is an uncommon, heritable condition triggered by anesthesia and is followed by an increase in temperature that may be fatal without prompt treatment. It is rare with desflurane and in black individuals of African descent. We present a case of malignant hyperthermia in an African-American patient during desflurane anesthesia.
authors.affiliation: Department of Anesthesiology, Mercer University School of Medicine, The Medical Center of Central Georgia, Macon, Georgia 31201, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Lane
authors.forename: A G
authors.initials: AG
authors.lastname: Brooks
authors.forename: M S
authors.initials: MS
authors.lastname: Logan
authors.forename: W H
authors.initials: WH
authors.lastname: Newman
authors.forename: M R
authors.initials: MR
authors.lastname: Castresana
mesh_terms: D000328:Adult; D001741:Black or African American; D000732:Androstanols / Q000008:administration & dosage; D000769:Anesthesia, Inhalation / Q000009:adverse effects; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D044383:Black People; D003620:Dantrolene / Q000627:therapeutic use; D000077335:Desflurane; D005147:Facial Bones / Q000293:injuries; D005283:Fentanyl / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D007530:Isoflurane / Q000009:adverse effects* / Q000031:analogs & derivatives*; D008297:Male; D008305:Malignant Hyperthermia / Q000188:drug therapy / Q000209:etiology*; D008874:Midazolam / Q000008:administration & dosage; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage; D009609:Nitrous Oxide / Q000008:administration & dosage; D000077123:Rocuronium; D012887:Skull Fractures / Q000601:surgery
chemical_list: D000732:Androstanols; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D009125:Muscle Relaxants, Central; D003473:Neuromuscular Nondepolarizing Agents; D000077335:Desflurane; D007530:Isoflurane; D003620:Dantrolene; D009609:Nitrous Oxide; D008874:Midazolam; D005283:Fentanyl; D000077123:Rocuronium