title: Duration of viraemia and faecal viral excretion in acute hepatitis E.
abstract: Data on duration of viral excretion and viraemia during hepatitis E virus (HEV) infection are limited. We tested serial stool and serum samples from 20 patients with acute hepatitis E for HEV RNA. Faecal excretion and viraemia in these patients were found to be short lived. In 19 patients, all samples obtained after biochemical resolution of hepatitis tested negative; in the remaining patient, HEV RNA was detected in the serum samples but not in stool after biochemical resolution. Long-term persistence of HEV in body fluids of infected individuals seems to be an unlikely reservoir for transmission of HEV.
authors.forename: R
authors.initials: R
authors.lastname: Aggarwal
authors.forename: D
authors.initials: D
authors.lastname: Kini
authors.forename: S
authors.initials: S
authors.lastname: Sofat
authors.forename: S R
authors.initials: SR
authors.lastname: Naik
authors.forename: K
authors.initials: K
authors.lastname: Krawczynski
mesh_terms: D000208:Acute Disease; D000328:Adult; D005243:Feces / Q000821:virology*; D016751:Hepatitis E / Q000097:blood / Q000821:virology*; D016752:Hepatitis E virus / Q000235:genetics; D006801:Humans; D012367:RNA, Viral / Q000097:blood; D013997:Time Factors; D014766:Viremia / Q000821:virology*
chemical_list: D012367:RNA, Viral