G-protein coupled progesterone receptors in the plasma membrane of fungus Rhizopus nigricans.
We have demonstrated simultaneous existence of progesterone receptors and GTPase activity in the membranes prepared from the filamentous fungus Rhizopus nigricans. The results obtained with pertussis toxin treated fungal mycelium suggest that these receptors do not couple to Gi-Go-proteins and play a role in the induction of steroid hydroxylating enzyme system by steroid substrates in the fungus.
Bavec
A
A
Institute of Biochemistry, Medical Faculty, University of Ljubljana, Slovenia.
Slajpah
M
M
Lenasi
H
H
Yorko
M
M
Breskvar
K
K
D001667:Binding, Competitive; D002462:Cell Membrane / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D020558:GTP Phosphohydrolases / Q000378:metabolism; D019204:GTP-Binding Proteins / Q000378:metabolism*; D011374:Progesterone / Q000494:pharmacology; D011980:Receptors, Progesterone / Q000145:classification / Q000378:metabolism*; D012233:Rhizopus / Q000378:metabolism*
D011980:Receptors, Progesterone; D011374:Progesterone; D020558:GTP Phosphohydrolases; D019204:GTP-Binding Proteins