title: Reversible pitch perception deficit caused by carbamazepine.
abstract: Carbamazepine (CBZ) is an antiepileptic drug frequently used to treat a variety of neurologic diseases or symptoms. In addition, the drug is used as a mood stabilizer in patients with affective or schizophrenic disorders. Among its adverse effects, auditory disturbance is described rarely. In this report, we describe a 25-year-old woman who noted falsely higher pitch perception after starting CBZ treatment for schizoaffective disorder. We also review the literature reporting CBZ-associated abnormal pitch perception.
authors.affiliation: Department of Psychiatry, Shimane Medical University, Izumo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Miyaoka
authors.forename: H
authors.initials: H
authors.lastname: Seno
authors.forename: M
authors.initials: M
authors.lastname: Itoga
authors.forename: J
authors.initials: J
authors.lastname: Horiguchi
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D002220:Carbamazepine / Q000009:adverse effects* / Q000627:therapeutic use; D003072:Cognition Disorders / Q000139:chemically induced* / Q000523:psychology; D005260:Female; D006801:Humans; D010898:Pitch Perception / Q000187:drug effects*; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000150:complications / Q000523:psychology
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine