title: Quantitative analysis of potential transfer of continuous glass filament from eclipse prototype 9-014 cigarettes.
abstract: This study was designed to determine if the Eclipse prototype 9-014 cigarettes, which use a special form of continuous glass filament (CGF) as an insulator around the carbon heat source, yield CGFs via mainstream smoke. A previously developed method (Higuchi et al., 2000) that employed electrostatic precipitation-with a greater than 99% collection efficiency of mass-was used to capture CGFs transferred to mainstream smoke. The cigarettes were smoked using an exaggerated puffing condition more than twice the Federal Trade Commission (FTC) standard. Prior to smoking, cigarettes were subjected to handling procedures that simulated commercial shipping conditions. Using a modified standard addition method, and utilizing a mixture of water and glycerol as a mock condensate, CGFs were intentionally added to a series of (mock condensate) samples to develop knowledge of CGF recovery efficiency. The linear regression model of the recovered CGFs demonstrated a recovery efficiency of 86%. This efficiency rate was applied to the number of CGFs recovered from samples of smoke condensate and associated background samples. The number of CGFs in smoke condensate collected from the Eclipse 9-014 prototype was approximately 0.32 +/- 0.17 CGFs per cigarette (+/- standard deviation), including the background counts of CGFs, and 0.16 CGFs per cigarette when corrected for background contributions. The number of CGFs found in the smoke condensates for this prototype was statistically (p =.00031) distinguishable from zero and background in these experiments. The low number of CGFs seen in the transfer data from this prototype studied, the unique physical characteristics of the filaments (e.g., controlled physical dimensions), and the absence of biological activity of similar glass filaments/fibers indicate that biologically significant exposure to the Eclipse smoker does not occur.
authors.affiliation: Research and Development Department, R. J. Reynolds Tobacco Company, PO Box 1236, Winston-Salem, NC 27102, USA. higuchm@rjrt.com
authors.forename: M A
authors.initials: MA
authors.lastname: Higuchi
authors.forename: P H
authors.initials: PH
authors.lastname: Ayres
authors.forename: J E
authors.initials: JE
authors.lastname: Swauger
authors.forename: W T
authors.initials: WT
authors.lastname: Morgan
authors.forename: A T
authors.initials: AT
authors.lastname: Mosberg
mesh_terms: D006801:Humans; D010947:Plants, Toxic; D012044:Regression Analysis; D012906:Smoke / Q000032:analysis*; D012907:Smoking; D014026:Nicotiana
chemical_list: D012906:Smoke