title: Preload dependence of color M-mode Doppler flow propagation velocity in controls and in patients with left ventricular dysfunction.
abstract: The purpose of this study was to assess the effects of preload alterations on color M-mode flow propagation velocity (Vp) in volunteers with normal left ventricular (LV) function and in patients with depressed LV function. Color M-mode Doppler echocardiography was performed during Valsalva maneuver, passive leg lifting, and after administration of nitroglycerin in 30 healthy volunteers and in 30 age- and sex-matched patients with previous myocardial infarction (MI). Mean Vp in controls was 74 +/- 15 cm/s at baseline and 46 +/- 15 cm/s in MI patients (P <.0005). In both groups, minor changes in Vp were seen during preload alterations; however, these were not significant (control P =.72, MI P =.31). In both groups, peak E-wave velocity (P <.0005), ratio of early-to-late peak velocities (P <.0005), and E-wave deceleration time (P <.0005) were found to change during preload alterations. In conclusion, we found that in controls and patients with previous MI, the color M-mode flow propagation velocity is not affected significantly by preload.
authors.affiliation: Department of Medicine, Svendborg Hospital, Denmark. jam@shf.fyns-amt.dk
authors.forename: J E
authors.initials: JE
authors.lastname: Møller
authors.forename: S H
authors.initials: SH
authors.lastname: Poulsen
authors.forename: E
authors.initials: E
authors.lastname: Søndergaard
authors.forename: K
authors.initials: K
authors.lastname: Egstrup
mesh_terms: D000368:Aged; D001783:Blood Flow Velocity; D018618:Echocardiography, Doppler, Color; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging*; D016277:Ventricular Function, Left