Three methoxy-substituted diethyl 4-phenyl-2,6-dimethyl-1, 4-dihydropyridine-3,5-dicarboxylate compounds.
Diethyl 4-(2,5-dimethoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3, 5-dicarboxylate, C(21)H(27)NO(6), (I), diethyl 4-(3, 4-dimethoxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3, 5-dicarboxylate, C(21)H(27)NO(6), (II), and diethyl 2, 6-dimethyl-4-(3,4,5-trimethoxyphenyl)-1,4-dihydropyridine-3, 5-dicarboxylate, C(22)H(29)NO(7), (III), crystallize with hydrogen-bonding networks involving the H atom bonded to the N atom of the 1,4-dihydropyridine ring and carbonyl O atoms in (I) and (II). Unusually, (III) shows O atoms of methoxy groups serving as hydrogen-bond acceptors.
Metcalf
S K
SK
Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, USA.
Holt
E M
EM
D000959:Antihypertensive Agents / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004095:Dihydropyridines / Q000737:chemistry*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008968:Molecular Conformation
D000959:Antihypertensive Agents; D004095:Dihydropyridines