Sequestration of TT virus of restricted genotypes in peripheral blood mononuclear cells.
Peripheral blood mononuclear cells (PBMC) harbored TT virus (TTV) of genotypes (3 and 4) different from those (1 and 2) of free virions in plasma of the same individuals. PBMC may act as a reservoir, and TTV of particular genotypes might have tropism for hematopoietic cells.
Okamoto
H
H
Immunology Division and Division of Molecular Virology, Jichi Medical School, Tochigi-Ken 329-0498, Japan.
Takahashi
M
M
Kato
N
N
Fukuda
M
M
Tawara
A
A
Fukuda
S
S
Tanaka
T
T
Miyakawa
Y
Y
Mayumi
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D004266:DNA Virus Infections / Q000821:virology*; D004279:DNA, Viral / Q000097:blood; D005260:Female; D005838:Genotype; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000821:virology*; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods; D017422:Sequence Analysis, DNA; D022783:Torque teno virus / Q000235:genetics* / Q000502:physiology*; D020506:Untranslated Regions / Q000235:genetics
D004279:DNA, Viral; D020506:Untranslated Regions