title: Pathology of femoral head collapse following transtrochanteric rotational osteotomy for osteonecrosis.
abstract: We investigated the pathology of femoral head collapse following transtrochanteric anterior rotational osteotomy. Six femoral heads were obtained during total hip arthroplasty some 2-12 years after osteotomy. In all cases, the preoperatively necrotic lesions exhibited mostly osteonecrosis with accumulation of bone marrow cell debris and trabecular bone with empty lacunae, although repair tissue such as granulation tissue and appositional bone formation were observed in limited areas in some cases. In the transposed intact articular surface of the femoral head, osteoarthritic changes such as fissure penetration to the subchondral bone and osteophyte formation were commonly observed. In newly created subchondral areas at weight-bearing sites, trabecular thickness and the number of trabecular bones had decreased, with few osteoblasts, osteoclasts, and osteocytes being present, resulting in a coarse lamellar structure of the trabecular bone. These findings suggest that transposed areas in cases of failure consist mostly of low-turnover osteoporotic lesions which could cause collapse of the femoral head.
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Medical School, Suita, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nakai
authors.forename: K
authors.initials: K
authors.lastname: Masuhara
authors.forename: T
authors.initials: T
authors.lastname: Nakase
authors.forename: N
authors.initials: N
authors.lastname: Sugano
authors.forename: K
authors.initials: K
authors.lastname: Ohzono
authors.forename: T
authors.initials: T
authors.lastname: Ochi
mesh_terms: D000328:Adult; D005260:Female; D005269:Femur / Q000473:pathology*; D005271:Femur Head Necrosis / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010027:Osteotomy / Q000379:methods*