title: The unclampable ascending aorta in coronary artery bypass patients: A surgical challenge of increasing frequency.
abstract: BACKGROUND
  The unclampable ascending aorta (UAA) is a condition increasingly encountered during CABG procedures. We report our experience with CABG patients with UAA and place particular emphasis on the preoperative diagnosis and surgical management.
  
  
  RESULTS
  UAA was diagnosed in 211 of 4812 consecutive CABG patients (4.3%). On the basis of the chest radiograph, echocardiogram, and coronary angiograph, a preoperative diagnosis was achieved in only 58 patients (27.4%). An age of >70 years, diabetes, smoking, unstable angina, diffuse coronaropathy, and peripheral vasculopathy were all predictors of UAA. Patients were treated with hypothermic ventricular fibrillation (no-touch technique n=129) or beating heart revascularization (no-pump technique n=82) depending on the possibility of founding an arterial cannulation site. The overall in-hospital mortality rate was 2.8% (6 of 211) with no differences between the 2 surgical strategies. The no-touch technique was associated with a greater incidence of neurological complications (stroke and transient ischemic attack), renal insufficiency, and stay in the intensive care unit and hospital. However, at midterm follow-up, more patients of the no-pump group had ischemia recurrence.
  
  
  CONCLUSIONS
  A preoperative diagnosis of UAA is achievable only in a minority of patients, which highlights the necessity revising the current diagnostic protocols. The use of the no-touch technique is associated with an high perioperative risk but a superior possibility of complete revascularization, whereas adoption of the no-pump strategy ensures a smoother postoperative course at the expense of an higher incidence of ischemia recurrence.
authors.affiliation: Department of Cardiac Surgery, Catholic University, Rome, Italy. mgaudino@tiscalinet.it
authors.forename: M
authors.initials: M
authors.lastname: Gaudino
authors.forename: F
authors.initials: F
authors.lastname: Glieca
authors.forename: F
authors.initials: F
authors.lastname: Alessandrini
authors.forename: N
authors.initials: N
authors.lastname: Luciani
authors.forename: C
authors.initials: C
authors.lastname: Cellini
authors.forename: C
authors.initials: C
authors.lastname: Pragliola
authors.forename: G
authors.initials: G
authors.lastname: Possati
mesh_terms: D000368:Aged; D001011:Aorta / Q000601:surgery*; D002318:Cardiovascular Diseases / Q000401:mortality / Q000601:surgery*; D001026:Coronary Artery Bypass / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests