Maturation hierarchy of leukemic stem cells.
Here we discuss the characteristics of various progenitor cell assays for human acute myeloid leukemia (AML) with emphasis on the repopulating properties of human AML progenitor cells, their potential relevance for pathophysiological studies, and treatment development in AML.
Löwenberg
B
B
University Hospital Rotterdam and Erasmus University, The Netherlands.
Terpstra
W
W
D003114:Colony-Forming Units Assay; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000276:immunology / Q000473:pathology*; D006801:Humans; D016130:Immunophenotyping; D015470:Leukemia, Myeloid, Acute / Q000097:blood / Q000473:pathology* / Q000628:therapy*