title: Novel approaches to the biosynthesis of vanillin.
abstract: Microorganisms able to produce vanillin in excess of 6g/l from ferulic acid have now been isolated. In Pseudomonas strains, the metabolic pathway from eugenol via ferulic acid to vanillin has been characterised at the enzymic and molecular genetic levels. Attempts to introduce vanillin production into other organisms by genetic engineering have begun.
authors.affiliation: Food Safety Science Division, Institute of Food Research, Norwich Research Park, Colney, NR4 7UA, Norwich, UK. nicholas.walton@bbsrc.ac.uk
authors.forename: N J
authors.initials: NJ
authors.lastname: Walton
authors.forename: A
authors.initials: A
authors.lastname: Narbad
authors.forename: C
authors.initials: C
authors.lastname: Faulds
authors.forename: G
authors.initials: G
authors.lastname: Williamson
mesh_terms: D001547:Benzaldehydes / Q000378:metabolism*; D001709:Biotechnology / Q000379:methods*; D003373:Coumaric Acids / Q000378:metabolism; D005054:Eugenol / Q000378:metabolism; D005421:Flavoring Agents / Q000378:metabolism*; D005524:Food Technology / Q000379:methods*; D005818:Genetic Engineering; D003904:Mitosporic Fungi / Q000378:metabolism; D010330:Patents as Topic; D011551:Pseudomonas fluorescens / Q000378:metabolism
chemical_list: D001547:Benzaldehydes; D003373:Coumaric Acids; D005421:Flavoring Agents; D005054:Eugenol; C004999:ferulic acid; C100058:vanillin