Non-linear signaling for pattern formation?
Developmental pathways are often simplified as linear cascades of gene activation caused by initial signaling events. Recent data, however, support a more complex view in which non-linear responses to signals are important for pattern formation. First, a positive feedback loop may regulate cellular patterning in the Arabidopsis epidermis. Second, an asymmetric auxin distribution that organizes pattern in the distal root tip may be established by positive feedback.
Scheres
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Department of Molecular Cell Biology, Utrecht University, The Netherlands. b.scheres@bio.uu.nl
D017360:Arabidopsis / Q000254:growth & development*; D019521:Body Patterning; D002450:Cell Communication; D018518:Plant Root Cap / Q000254:growth & development; D018517:Plant Roots / Q000254:growth & development*