title: Endogenous digitalislike factor: an update.
abstract: This issue of Hypertension Research contains the review and original articles presented at the International Symposium on Natriuretic and Digitalis-Like Factors held in Chitose, Hokkaido, Japan, on August 24, 1999. The symposium was the satellite meeting of the 9th International Conference on the Na/K-ATPase and Related ATPases, which was held in Sapporo, Hokkaido. At the symposium, it became clear that ouabain is the most promising candidate for a circulating hormone to regulate a number of physiological functions, including hypertension, and that other minor substances may also exist as endogenous digitalislike factors. Most of the symposium contributors submitted papers to this journal. I am going to summarize briefly the research history and current research results on endogenous digitalislike factors (EDLF).
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
mesh_terms: D000818:Animals; D002298:Cardenolides; D004077:Digoxin; D006801:Humans; D006973:Hypertension / Q000378:metabolism* / Q000503:physiopathology*; D012503:Saponins / Q000378:metabolism*
chemical_list: D002298:Cardenolides; D012503:Saponins; C034504:digoxin-like factors; D004077:Digoxin