title: Safety of femoral closure devices after percutaneous coronary interventions in the era of glycoprotein IIb/IIIa platelet blockade.
abstract: We compared in-hospital femoral complications of Angio-Seal, Perclose, and manual compression in consecutive patients who underwent percutaneous coronary interventions in the era of glycoprotein IIb/IIIa platelet inhibition. Femoral closure devices have a similar overall risk profile as manual compression, even in patients treated with glycoprotein IIb/IIIa platelet inhibition, although certain rare complications such as retroperitoneal hemorrhage and severe access-site infection may be more common with the use of these devices.
authors.affiliation: Department of Cardiology, Cleveland Clinic Foundation, Ohio, USA.
authors.forename: F A
authors.initials: FA
authors.lastname: Cura
authors.forename: S R
authors.initials: SR
authors.lastname: Kapadia
authors.forename: P L
authors.initials: PL
authors.lastname: L'Allier
authors.forename: J P
authors.initials: JP
authors.lastname: Schneider
authors.forename: M S
authors.initials: MS
authors.lastname: Kreindel
authors.forename: M J
authors.initials: MJ
authors.lastname: Silver
authors.forename: J S
authors.initials: JS
authors.lastname: Yadav
authors.forename: C C
authors.initials: CC
authors.lastname: Simpfendorfer
authors.forename: R R
authors.initials: RR
authors.lastname: Raymond
authors.forename: E M
authors.initials: EM
authors.lastname: Tuzcu
authors.forename: I
authors.initials: I
authors.lastname: Franco
authors.forename: P L
authors.initials: PL
authors.lastname: Whitlow
authors.forename: E J
authors.initials: EJ
authors.lastname: Topol
authors.forename: S G
authors.initials: SG
authors.lastname: Ellis
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D005260:Female; D005263:Femoral Artery / Q000293:injuries; D006489:Hemostatic Techniques / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors*; D011312:Pressure / Q000009:adverse effects; D011446:Prospective Studies; D012044:Regression Analysis; D012449:Safety; D013536:Suture Techniques / Q000009:adverse effects; D014652:Vascular Diseases / Q000209:etiology*
chemical_list: D019039:Platelet Glycoprotein GPIIb-IIIa Complex