title: Gene delivery to the corneal endothelium.
abstract: Gene transfer to the corneal endothelium has potential for modulating rejection of corneal grafts. It can also serve as a convenient and useful model for gene therapy of other organs. In this article we review the work carried out in our laboratory using both viral and nonviral vectors to obtain gene expression in the cornea.
authors.affiliation: Department of Immunology, Division of Medicine, Imperial College, Hammersmith Hospital, London; and Moorfields Eye Hospital, London, United Kingdom.
authors.forename: A J
authors.initials: AJ
authors.lastname: George
authors.forename: C V
authors.initials: CV
authors.lastname: Arancibia-Cárcamo
authors.forename: H M
authors.initials: HM
authors.lastname: Awad
authors.forename: R M
authors.initials: RM
authors.lastname: Comer
authors.forename: Z
authors.initials: Z
authors.lastname: Fehevari
authors.forename: W J
authors.initials: WJ
authors.lastname: King
authors.forename: M
authors.initials: M
authors.lastname: Kadifachi
authors.forename: T
authors.initials: T
authors.lastname: Hudde
authors.forename: C
authors.initials: C
authors.lastname: Kerouedan-Lebossé
authors.forename: F
authors.initials: F
authors.lastname: Mirza
authors.forename: H
authors.initials: H
authors.lastname: Barbaros Oral
authors.forename: S A
authors.initials: SA
authors.lastname: Rayner
authors.forename: P H
authors.initials: PH
authors.lastname: Tan
authors.forename: E
authors.initials: E
authors.lastname: Tay
authors.forename: D F
authors.initials: DF
authors.lastname: Larkin
mesh_terms: D000256:Adenoviridae / Q000235:genetics; D000818:Animals; D004728:Endothelium, Corneal / Q000473:pathology*; D018014:Gene Transfer Techniques; D005822:Genetic Vectors; D006084:Graft Rejection / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D006801:Humans; D023001:Transplantation Tolerance / Q000235:genetics