title: Total synthesis of (-)-ascochlorin via a cyclobutenone-based benzannulation strategy.
abstract: The application of a convergent benzannulation strategy in an efficient synthesis of (-)-ascochlorin is described.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
authors.forename: G B
authors.initials: GB
authors.lastname: Dudley
authors.forename: K S
authors.initials: KS
authors.lastname: Takaki
authors.forename: D D
authors.initials: DD
authors.lastname: Cha
authors.forename: R L
authors.initials: RL
authors.lastname: Danheiser
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis*; D003503:Cyclobutanes / Q000737:chemistry*; D010636:Phenols / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D003503:Cyclobutanes; D010636:Phenols; C415745:ascochlorin