Mechanism of pulmonary vein stenosis in infants with normally connected veins.
We used microscopy, immunohistochemistry, and cell culture to identify the mechanism of restenosis in 4 infants with isolated pulmonary vein stenosis. Recurrent obstruction appears to be due to myofibroblastic proliferation in this fatal disease.
Sadr
I M
IM
Department of Cardiology, Children's Hospital, Boston, Massachusetts 02115, USA.
Tan
P E
PE
Kieran
M W
MW
Jenkins
K J
KJ
D003251:Constriction, Pathologic / Q000473:pathology / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011667:Pulmonary Veins / Q000002:abnormalities* / Q000473:pathology*