Is a second urine specimen necessary for the diagnosis of asymptomatic bacteriuria?
By use of pulse-field gel electrophoresis, we evaluated the molecular identity of 32 Escherichia coli isolates obtained in 2 consecutive urine cultures from 16 patients as part of a large study of asymptomatic bacteriuria in diabetic women and found different E. coli isolates in 7 of 16 patients, meaning that nearly half (44%) of the patients who had been previously classified as having asymptomatic bacteriuria were reinfected with a different strain.
Geerlings
S E
SE
Department of Internal Medicine, Division of Infectious Diseases and AIDS, University Hospital Utrecht, Utrecht, The Netherlands.
Brouwer
E C
EC
Gaastra
W
W
Hoepelman
A I
AI
D001437:Bacteriuria / Q000175:diagnosis* / Q000382:microbiology / Q000652:urine*; D004269:DNA, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D004926:Escherichia coli / Q000235:genetics / Q000302:isolation & purification; D005260:Female; D006801:Humans
D004269:DNA, Bacterial