title: [Initial superficial bladder tumors: our experience. Our criteria. Study Group of Bladder Tumors].
abstract: OBJECTIVE
  Evaluation of a homogeneous series of Superficial Primary TCC of the Bladder. Utility of randomized biopsies (BMN). Study of risk factors and risk groups as a basis for determining treatment and followup patterns.
  
  
  METHODS
  Survey of 1,529 PSBT cases that underwent TURB and BMN, with a mean followup of 4.2 years. Strict statistical treatment: multivariate analysis using Cox logistic regression according to Kaplan-Meier curves.
  
  
  RESULTS
  Tumor features of note: single tumor (65%), smaller than 1.5 cm (45%), high grade (G3: 26%), and high stage (T1: 64%). BMN showed associated CIS in 284 cases (19%). Main risk factors for recurrence were multiplicity, size > 3 cm and association with CIS. The main risk factor for progression was grade 3 (OR 19.9). Grade 3 and association with CIS were found to increase mortality risk. On the basis of this data, we grouped tumors according to low-, middle-, and high-risk, and established our proposed treatment and followup for each group.
  
  
  CONCLUSIONS
  This multivariate analysis of a homogeneous cohort of 1,529 primary superficial bladder tumor cases allowed vs to determine risk groups for treatment and followup.
authors.affiliation: Servicio de Urología, Fundació Puigvert, Barcelona.
authors.forename: J
authors.initials: J
authors.lastname: Vicente Rodríguez
authors.forename: J
authors.initials: J
authors.lastname: Salvador Bayarri
authors.forename: G
authors.initials: G
authors.lastname: Chéchile Toniolo
authors.forename: F
authors.initials: F
authors.lastname: Millán Rodríguez
authors.forename: J
authors.initials: J
authors.lastname: Palou Redorta
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D012307:Risk Factors; D001749:Urinary Bladder Neoplasms / Q000473:pathology*