When is a disease eradicable? 100 years of lessons learned.
Since the 1915 launch of the first international eradication initiative targeting a human pathogen, much has been learned about the determinants of eradicability of an organism. The authors outline the first 4 eradication efforts, summarizing the lessons learned in terms of the 3 types of criteria for disease eradication programs: (1) biological and technical feasibility, (2) costs and benefits, and (3) societal and political considerations.
Aylward
B
B
Expanded Programme on Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland. aylwardb@who.ch
Hennessey
K A
KA
Zagaria
N
N
Olivé
J M
JM
Cochi
S
S
D003140:Communicable Disease Control / Q000266:history*; D003362:Cost-Benefit Analysis; D004320:Dracunculiasis / Q000266:history / Q000517:prevention & control; D014943:Global Health; D049673:History, 20th Century; D006801:Humans; D008288:Malaria / Q000266:history / Q000517:prevention & control; D011051:Poliomyelitis / Q000266:history / Q000517:prevention & control; D012899:Smallpox / Q000266:history / Q000517:prevention & control; D015001:Yaws / Q000266:history / Q000517:prevention & control; D015004:Yellow Fever / Q000266:history / Q000517:prevention & control