title: [Parotid involvement in cat scratch disease: a differential diagnosis with increased significance].
abstract: BACKGROUND
  Bartonella henselae is the causative agent of cat-scratch disease (CSD), an inflammatory infection of the lymph nodes. So far, only few cases of atypical manifestations in the head and neck, especially manifestations in the parotid gland have been reported.
  
  
  METHODS
  Between January 1997 and June 1999 seven patients with manifestations of CSD in the parotid gland were observed at the ENT-department Freiburg. The positive diagnosis was confirmed serologically by an indirect immunofluorescence assay and by detection of Bartonella henselae-DNA with PCR-amplification and subsequent hybridization or sequencing.
  
  
  RESULTS
  An intraglandular abscessed lymphadenitis was found in five patients, two of these cases were based on a Parinaud's oculoglandular syndrome. A diffuse affection of the parotid gland, initially misinterpreted as a parotid tumor, was seen in two patients.
  
  
  CONCLUSIONS
  Antibiotic treatment is recommended in order to reduce the duration of the disease, in cases of pain and lymph node abscesses. In uncommon manifestations of CSD, the nosological assignment can be difficult on the basis of the heterogeneous symptomatic in the individual patient and the CSD diagnosis can only be confirmed by serology or PCR-based techniques. CSD should be considered in the differential diagnosis of all equivocal masses in the head and neck, even in unusual localisations like the parotid gland.
authors.affiliation: Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde und Poliklinik, Universitätsklinikum Freiburg. ridder@hno.ukl.uni-freiburg.de
authors.forename: G J
authors.initials: GJ
authors.lastname: Ridder
authors.forename: B
authors.initials: B
authors.lastname: Richter
authors.forename: R
authors.initials: R
authors.lastname: Laszig
authors.forename: A
authors.initials: A
authors.lastname: Sander
mesh_terms: D000038:Abscess / Q000175:diagnosis / Q000276:immunology; D000328:Adult; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D018416:Bartonella henselae / Q000235:genetics / Q000276:immunology; D002372:Cat-Scratch Disease / Q000175:diagnosis* / Q000276:immunology; D002415:Cats; D002675:Child, Preschool; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010309:Parotitis / Q000175:diagnosis* / Q000276:immunology; D016133:Polymerase Chain Reaction
chemical_list: D000907:Antibodies, Bacterial