title: Interstitial brachytherapy for recurrent breast cancer using a high dose rate Ir-192 remote afterloading system: a report of two cases.
abstract: We employed interstitial brachytherapy using a high dose rate Ir-192 remote afterloading unit in two breast cancer patients with locoregional recurrence. In the first case, skin metastasis was treated, with favorable control of the infield tumor but subsequent persistent sequelae and multiple outfield metastases. This experience caused us to be cautious when choosing brachytherapy for the second case, in whom a solitary metastasis to an axillary lymph node was successfully treated. Although this method is still investigational, it may play a critical role in the treatment of locoregional recurrence resistant to other treatment modalities.
authors.affiliation: Department of Radiology, Kobe University School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku Kobe, Hyogo 650-0017, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Yoden
authors.forename: J
authors.initials: J
authors.lastname: Hiratsuka
authors.forename: Y
authors.initials: Y
authors.lastname: Imajo
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: J
authors.initials: J
authors.lastname: Kurebayashi
authors.forename: K
authors.initials: K
authors.lastname: Shimozuma
authors.forename: H
authors.initials: H
authors.lastname: Sonoo
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D002293:Adenocarcinoma, Scirrhous / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D008408:Mastectomy; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D009367:Neoplasm Staging; D018579:Patient Selection; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D007496:Iridium Radioisotopes