Labial adenocarcinoma after treatment with cyclosporin a in a patient with panuveitis.
OBJECTIVE
To report a case of labial basal cell adenocarcinoma in a patient with uveitis on treatment with cyclosporin A.


METHODS
Case report. A 73-year-old woman with panuveitis and retinal vasculitis presented with a lump on her lip after 52 months of treatment with cyclosporin A.


RESULTS
Excision biopsy showed a labial adenocarcinoma.


CONCLUSIONS
Malignancy can occur after long-term cyclosporin A treatment for uveitis.
Ramchandani
M
M
Birmingham and Midland Eye Centre, Birmingham, United Kingdom.
Brown
A M
AM
Rippin
J W
JW
Murray
P I
PI
D000230:Adenocarcinoma / Q000139:chemically induced* / Q000473:pathology; D000368:Aged; D016572:Cyclosporine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008048:Lip Neoplasms / Q000139:chemically induced* / Q000473:pathology; D015864:Panuveitis / Q000188:drug therapy*; D011239:Prednisolone / Q000627:therapeutic use; D012164:Retinal Diseases / Q000188:drug therapy; D012171:Retinal Vessels / Q000187:drug effects; D014657:Vasculitis / Q000188:drug therapy
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011239:Prednisolone