title: Apparent progression of acute glomerulonephritis to dense deposit disease.
abstract: One week after the diagnosis of meningococcal meningitis, an 8-year-old boy presented with acute renal failure and hypocomplementemia. A renal biopsy showed "postinfectious glomerulonephritis" and acute tubular necrosis. Hematuria, proteinuria, and low complement levels persisted, and 2 years later a follow-up renal biopsy revealed dense deposit disease. The apparent progression of postinfectious glomerulonephritis to dense deposit disease as observed in this patient has not been previously described.
authors.affiliation: Department of Pathology, Tulane University School of Medicine, New Orleans, Louisiana 70112-2699, USA. mshadid@mailhost.tcs.tulane.edu
authors.forename: M
authors.initials: M
authors.lastname: Shahidi-Asl
authors.forename: M
authors.initials: M
authors.lastname: Ananth
authors.forename: F
authors.initials: F
authors.lastname: Boineau
authors.forename: S
authors.initials: S
authors.lastname: Meleg-Smith
mesh_terms: D000208:Acute Disease; D001706:Biopsy; D002648:Child; D018450:Disease Progression; D005500:Follow-Up Studies; D005921:Glomerulonephritis / Q000473:pathology*; D015432:Glomerulonephritis, Membranoproliferative / Q000473:pathology*; D006801:Humans; D007668:Kidney / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron