title: Alcohol neurolysis of the sciatic nerve in the treatment of hemiplegic knee flexor spasticity: clinical outcomes.
abstract: OBJECTIVE
  To study clinical outcomes after 50% to 100% alcohol neurolysis of the sciatic nerve in the treatment of chronic hemiplegic knee flexor spasticity.
  
  
  METHODS
  Case series using a convenience sample.
  
  
  METHODS
  Rehabilitation teaching hospital.
  
  
  METHODS
  Eight patients (mean age, 55.1 +/- 12.1 yr; mean duration to block, 4.4 +/- 3.7 mo) with chronic hemiplegia and severe spasticity (modified Ashworth scale [MAS] score < 2) secondary to cerebrovascular accidents (n = 5) and traumatic brain injuries (n = 3). Two patients were ambulant, 6 were wheelchair-bound.
  
  
  METHODS
  Fifty percent to 100% alcohol neurolysis of the sciatic nerve using repetitive electric stimulation to localize the sciatic nerve.
  
  
  METHODS
  MAS score, gain in knee range of motion (ROM), and visual inspection of gait at 0, 1, and 6 months postneurolysis. Nonparametric tests were used in statistical analysis.
  
  
  RESULTS
  The mean preinjection MAS score was 2.8 +/- 0.7, which improved to 1.4 +/- 0.7 at 1 month (p = .005), and 1.8 +/- 0.9 (p = .01) and 1.9 +/- 1.1 (p = .02) at 3 and 6 months postinjection, respectively. The mean gain in knee ROM was 34.4 degrees +/- 15.7 degrees at 1 month postinjection and was maintained at 6 months postinjection. Improvements in gait were noted in both ambulant patients, and improved positioning in 3 of 6 wheelchair-bound patients. The incidence of dysesthetic pain was 0%.
  
  
  CONCLUSIONS
  Fifty percent to 100% alcohol neurolysis of the sciatic nerve is a safe and effective method for treatment of hemiplegic knee flexor spasticity, with therapeutic effects lasting 6 months.
authors.affiliation: Department of Rehabilitation Medicine, Tan Tock Seng Hospital, Singapore, Republic of Singapore. karen_chua@notes.ttsh.gov.sg
authors.forename: K S
authors.initials: KS
authors.lastname: Chua
authors.forename: K H
authors.initials: KH
authors.lastname: Kong
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001930:Brain Injuries / Q000150:complications / Q000534:rehabilitation; D000431:Ethanol; D005260:Female; D006429:Hemiplegia / Q000150:complications / Q000534:rehabilitation*; D006801:Humans; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D009128:Muscle Spasticity / Q000209:etiology / Q000534:rehabilitation; D009407:Nerve Block / Q000379:methods*; D012584:Sciatic Nerve; D018709:Statistics, Nonparametric; D020521:Stroke / Q000150:complications; D000071939:Stroke Rehabilitation
chemical_list: D000431:Ethanol