title: Detection and quantitation of human immunodeficiency virus type 1 in the female genital tract. The Division of AIDS Treatment Research Initiative 009 Study Group.
abstract: Human immunodeficiency virus type 1 (HIV-1) was detected in the genital tracts of 59% of 225 women by RNA PCR and in 7% of the women by culture. In a comparison of two sampling methods, endocervical swabs were more sensitive than cervicovaginal lavage for HIV-1 RNA detection by PCR but not by culture and their sensitivity was independent of the concentration of HIV-1 RNA.
authors.affiliation: St. Luke's Hospital, New York, New York 10025, USA.
authors.forename: P
authors.initials: P
authors.lastname: Baron
authors.forename: J
authors.initials: J
authors.lastname: Bremer
authors.forename: S S
authors.initials: SS
authors.lastname: Wasserman
authors.forename: M
authors.initials: M
authors.lastname: Nowicki
authors.forename: B
authors.initials: B
authors.lastname: Driscoll
authors.forename: B
authors.initials: B
authors.lastname: Polsky
authors.forename: A
authors.initials: A
authors.lastname: Kovacs
authors.forename: P S
authors.initials: PS
authors.lastname: Reichelderfer
mesh_terms: D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000821:virology*; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D016133:Polymerase Chain Reaction / Q000379:methods; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014626:Vaginal Smears / Q000379:methods*
chemical_list: D012367:RNA, Viral