title: Suppression of intravascular signal on fat-saturated contrast-enhanced thoracic MR arteriograms.
abstract: OBJECTIVE
  To assess the prevalence of artifactual signal intensity loss within the aortic arch and proximal branch vessels on fat-saturated contrast material-enhanced magnetic resonance (MR) arteriograms of the thoracic aorta and to hypothesize about the cause of the loss of signal intensity.
  
  
  METHODS
  Between January and June 1998, 105 consecutive MR arteriograms of the thoracic aorta were acquired in 103 patients at 1.5 T. Imaging included an arterial phase three-dimensional (3D) fat-saturated contrast-enhanced gradient-echo (GRE) sequence followed by a delayed two-dimensional (2D) transverse fat-saturated GRE sequence. All MR images were reviewed by two radiologists who were blinded to patient history and results of imaging studies and who evaluated the images for the presence of intraluminal loss of signal intensity in the aortic arch and the proximal branch vessels.
  
  
  RESULTS
  Intravascular loss of signal intensity was present in at least one vessel on 23 of the 105 arterial phase 3D studies. Seventy-one of 91 left subclavian arterial segments had loss of signal intensity on the delayed 2D studies.
  
  
  CONCLUSIONS
  Intravascular signal intensity loss can be present on contrast-enhanced fat-saturated images of the aortic arch and proximal branch vessels, particularly the left subclavian artery. This phenomenon, which is to the authors' knowledge previously unreported and which is hypothesized to result from undesired water saturation, should not be misinterpreted as stenotic or occlusive vascular disease.
authors.affiliation: Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce St, 1st Floor Founders-MRI, Philadelphia, PA 19104-4283. USA. siegelm@oasis.rad.upenn.edu
authors.forename: E S
authors.initials: ES
authors.lastname: Siegelman
authors.forename: R
authors.initials: R
authors.lastname: Charafeddine
authors.forename: A H
authors.initials: AH
authors.lastname: Stolpen
authors.forename: L
authors.initials: L
authors.lastname: Axel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001013:Aorta, Thoracic; D017545:Aortic Aneurysm, Thoracic / Q000175:diagnosis; D001157:Arterial Occlusive Diseases / Q000175:diagnosis; D016477:Artifacts; D002648:Child; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA