title: Ornithobacterium rhinotracheale infection in turkeys: immunoprophylaxis studies.
abstract: Ornithobacterium rhinotracheale has been shown to cause serious clinical illness and is a significant concern to the turkey industry because of its potential economic impact. In this study, 6-wk-old turkeys were vaccinated intranasally with a live or subcutaneously with a killed O. rhinotracheale vaccine. At 14 or 21 wk of age, the birds were challenged intratracheally with live O. rhinotracheale. Airsacculitis and pneumonia occurred less frequently in vaccinated birds than in unvaccinated birds after challenge with O. rhinotracheale. Ornithobacterium rhinotracheale was recovered from unvaccinated, challenged birds but not from vaccinated, challenged or from unchallenged birds. Thus, turkeys inoculated with live or killed O. rhinotracheale vaccine were protected from pathologic changes.
authors.affiliation: Department of Veterinary PathoBiology, College of Veterinary Medicine, University of Minnesota, St. Paul 55108, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: Sprenger
authors.forename: D A
authors.initials: DA
authors.lastname: Halvorson
authors.forename: D P
authors.initials: DP
authors.lastname: Shaw
authors.forename: K V
authors.initials: KV
authors.lastname: Nagaraja
mesh_terms: D000400:Air Sacs / Q000382:microbiology / Q000473:pathology; D000818:Animals; D001428:Bacterial Vaccines; D006090:Gram-Negative Bacteria / Q000276:immunology* / Q000302:isolation & purification / Q000472:pathogenicity; D016905:Gram-Negative Bacterial Infections / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D008099:Liver / Q000473:pathology; D008168:Lung / Q000473:pathology; D008297:Male; D018410:Pneumonia, Bacterial / Q000473:pathology / Q000517:prevention & control / Q000662:veterinary; D011201:Poultry Diseases / Q000276:immunology / Q000382:microbiology* / Q000473:pathology; D013154:Spleen / Q000473:pathology; D014132:Trachea / Q000473:pathology; D014422:Turkeys; D015164:Vaccines, Inactivated
chemical_list: D001428:Bacterial Vaccines; D015164:Vaccines, Inactivated