[Primary large cell neuroendocrine carcinoma of the kidney: morphologic and immunohistochemical features of two cases].
Primary neuroendocrine carcinomas of the kidney are infrequent. The large cell neuroendocrine carcinoma is a subtype with an aggressive course and a worse prognosis. We report two cases, a 35-year-old man and a 75-year-old woman who died within 6 and 5-months after surgery despite radical nephrectomy and chemotherapy. Histological and immunohistochemical features are presented.
Moukassa
D
D
Services d'Anatomie et de Cytologie Pathologiques, Hôpital Calmette, CHRU 59037 Lille Cedex. d-moukassa@chru-lille.fr
Leroy
X
X
Bouchind'homme
B
B
Saint
F
F
Lemaître
L
L
Gosselin
B
B
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018278:Carcinoma, Neuroendocrine / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008297:Male; D009392:Nephrectomy; D013311:Streptozocin / Q000008:administration & dosage
D013311:Streptozocin; D004317:Doxorubicin