Influence of a single treatment with vitamin E or K (hormonal imprinting) of neonatal rats on the sexual behavior of adults.
The effect of a single neonatal treatment (imprinting) with vitamin E or vitamin K1 on the sexual activity of three-month old rats, was studied. In female animals vitamin E treatment significantly lowered the Meyerson index and lordosis quotient, among males there were significantly more inactive animals and no multiple ejaculations could be observed. Vitamin K1 treatment caused only slight changes in the same direction, in both sexes. Considering also earlier results concerning vitamin A and D neonatal treatments (alterations in receptor binding capacity, sex hormone levels and sexual behavior), and receptorial changes caused by neonatal vitamin E and K1 treatments, the present experiment also calls attention to the lifelong effects of perinatal treatment with lipid soluble vitamins.
Csaba
G
G
Department of Genetics, Cell and Immunobiology, Semmelweis University of Medicine, Budapest, Hungary. csagyor@net.sote.hu
Karabélyos
C S
CS
D000818:Animals; D000831:Animals, Newborn; D005260:Female; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D011956:Receptors, Cell Surface / Q000187:drug effects / Q000502:physiology; D011965:Receptors, Glucocorticoid / Q000187:drug effects / Q000502:physiology; D011973:Receptors, LDL / Q000187:drug effects / Q000502:physiology; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D014810:Vitamin E / Q000494:pharmacology*; D010837:Vitamin K 1 / Q000494:pharmacology*
D011956:Receptors, Cell Surface; D011965:Receptors, Glucocorticoid; D011973:Receptors, LDL; C027656:alpha-tocopherol receptor; D014810:Vitamin E; D010837:Vitamin K 1