title: Relationship between preoperative patency of the inferior mesenteric artery and subsequent occurrence of type II endoleak in patients undergoing endovascular repair of abdominal aortic aneurysms.
abstract: OBJECTIVE
  The purpose of this study was (1) to find out whether preoperative inferior mesenteric artery (IMA) patency (on radiographic imaging) predicts IMA-related endoleaks after endovascular repair of infrarenal abdominal aortic aneurysms, (2) to determine feasibility of measuring aneurysm sac pressures in patients with endoleaks, and (3) to report early evidence of effective endovascular obliteration of IMA endoleaks.
  
  
  METHODS
  We studied 76 consecutive cases of infrarenal aortic aneurysms that were repaired with an endovascular approach (March 1998-April 1999).
  
  
  RESULTS
  There were 13 (17%) endoleaks persistent 30 days after the procedure. Eleven (85%) of these 13 were IMA-related endoleaks, which were documented with selective superior mesenteric artery angiography. The preoperative finding (on computed tomographic scan) of a patent IMA does not always predict an IMA-related endoleak, but results in a statistically and clinically significant higher ratio of patients with IMA-related endoleaks in the immediate postoperative period (24% versus 3%, P <.035). In eight of the 11 patients with persistent IMA-related endoleaks, measurement of intra-aneurysm sac pressures was possible, and six of these patients had systemic pressures within the excluded aneurysm sac. Nine (82%) of 11 IMA-related endoleaks were successfully obliterated by means of selective IMA embolization.
  
  
  CONCLUSIONS
  Many endoleaks are caused by a patent IMA, and this can result in persistence of systemic pressure within the aneurysm sac. The preoperative finding (on computed tomographic scan) of a patent IMA is a predictor of increased rates of IMA endoleaks, and IMA endoleaks can be successfully obliterated through endovascular procedures, after endovascular abdominal aortic aneurysm repair.
authors.affiliation: Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA.
authors.forename: O C
authors.initials: OC
authors.lastname: Velazquez
authors.forename: R A
authors.initials: RA
authors.lastname: Baum
authors.forename: J P
authors.initials: JP
authors.lastname: Carpenter
authors.forename: M A
authors.initials: MA
authors.lastname: Golden
authors.forename: M
authors.initials: M
authors.lastname: Cohn
authors.forename: A
authors.initials: A
authors.lastname: Pyeron
authors.forename: C F
authors.initials: CF
authors.lastname: Barker
authors.forename: F J
authors.initials: FJ
authors.lastname: Criado
authors.forename: R M
authors.initials: RM
authors.lastname: Fairman
mesh_terms: D017544:Aortic Aneurysm, Abdominal / Q000503:physiopathology / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation; D004621:Embolization, Therapeutic; D005240:Feasibility Studies; D006439:Hemodynamics; D006801:Humans; D017537:Mesenteric Artery, Inferior; D017538:Mesenteric Artery, Superior; D011183:Postoperative Complications / Q000628:therapy; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014654:Vascular Patency