Is there a connection between the concentration of cholesterol circulating in plasma and the rate of neuritic plaque formation in Alzheimer disease?
Haley
R W
RW
University of Texas Southwestern Medical Center, Department of Internal Medicine, 5323 Harry Hines Blvd, Dallas, TX 75390-8874, USA.
Dietschy
J M
JM
D000544:Alzheimer Disease / Q000378:metabolism*; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D000924:Anticholesteremic Agents / Q000627:therapeutic use; D001057:Apolipoproteins E / Q000378:metabolism; D002784:Cholesterol / Q000097:blood*; D002986:Clinical Trials as Topic; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy / Q000378:metabolism; D016501:Neurites / Q000378:metabolism*; D016874:Neurofibrillary Tangles / Q000378:metabolism*; D017035:Pravastatin / Q000627:therapeutic use
D016229:Amyloid beta-Peptides; D000924:Anticholesteremic Agents; D001057:Apolipoproteins E; D002784:Cholesterol; D017035:Pravastatin