Identification of a new HLA-B*78 allele in a Hispanic family.
A new B*78 variant, B*7804, was detected in three members of a Hispanic family. The novel B*78 sequence differs from B*78021 by two substitutions: T at nucleotide 527 (all other B*78s have A) and T at nucleotide 583 (all other B*78s have a C). Both nucleotide substitutions encode amino acid changes at codons 152 and 171, respectively.
Gaidulis
L
L
Department of Hematology/Bone Marrow Transplantation, City of Hope Medical Center, Duarte, California, USA.
Krausa
P
P
Schaub
B
B
Senitzer
D
D
D000483:Alleles; D005091:Exons; D005192:Family Health; D015235:HLA-B Antigens / Q000235:genetics* / Q000276:immunology; D006630:Hispanic or Latino / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D020641:Polymorphism, Single Nucleotide / Q000276:immunology; D012689:Sequence Homology, Nucleic Acid
D015235:HLA-B Antigens