title: A synthetic transmembrane polyether model active in lipid bilayers.
abstract: A model polyether-based ion channel-like compound was rationally designed and synthesized. Macromolecules 1c-f were incorporated into phospholipid vesicles and shown to facilitate the transmembrane sodium transport.
authors.affiliation: Instituto de Investigaciones Químicas, CSIC, Américo Vespucio, s/n, Isla de la Cartuja, 41092 Seville, Spain.
authors.forename: C G
authors.initials: CG
authors.lastname: Espínola
authors.forename: R
authors.initials: R
authors.lastname: Pérez
authors.forename: J D
authors.initials: JD
authors.lastname: Martín
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D004987:Ethers / Q000138:chemical synthesis* / Q000737:chemistry; D008051:Lipid Bilayers / Q000737:chemistry*; D008567:Membranes, Artificial; D008958:Models, Molecular; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D015221:Potassium Channels / Q000737:chemistry; D011487:Protein Conformation; D012979:Sodium Radioisotopes
chemical_list: D000475:Alkenes; D004987:Ethers; D008051:Lipid Bilayers; D008567:Membranes, Artificial; D011108:Polymers; D015221:Potassium Channels; D012979:Sodium Radioisotopes