Detection of acetylcholinesterase activity and gamma-aminobutyric acid binding sites in Dicrocoelium dendriticum.
In the present study we report the presence of acetylcholinesterase activity and gamma-aminobutyric acid binding sites in crude extracts of Dicrocoelium dendriticum. This indirectly demonstrates the presence of acetylcholine and GABA. The presence of these neurotransmitters could indicate the existence of two systems implicated in the neurotransmission of the Digenea.
Giménez-Pardo
C
C
Parasitology Laboratory, Faculty of Pharmacy, University of Alcalá, Crtra, Madrid, Spain. consuelo.gimenez@uah.es
Ros-Moreno
R M
RM
De Armas-Serra
C
C
Rodriguez-Caabeiro
F
F
D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D001652:Bile Ducts / Q000469:parasitology; D001665:Binding Sites; D004011:Dicrocoeliasis / Q000662:veterinary; D004013:Dicrocoelium / Q000378:metabolism*; D005260:Female; D005704:Gallbladder / Q000469:parasitology; D008297:Male; D012756:Sheep; D012757:Sheep Diseases / Q000469:parasitology; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D005680:gamma-Aminobutyric Acid; D000110:Acetylcholinesterase