The gene guessing game.
A recent flurry of publications and media attention has revived interest in the question of how many genes exist in the human genome. Here, I review the estimates and use genomic sequence data from human chromosomes 21 and 22 to establish my own prediction.
Dunham
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The Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
D001483:Base Sequence; D002891:Chromosomes, Human, Pair 21 / Q000235:genetics; D002892:Chromosomes, Human, Pair 22 / Q000235:genetics; D019295:Computational Biology; D018899:CpG Islands; D020224:Expressed Sequence Tags; D005796:Genes; D015894:Genome, Human; D023281:Genomics; D006801:Humans