title: Predictors of an antibiotic prescription by GPs for respiratory tract infections: a pilot.
abstract: BACKGROUND
  Antibiotics are over-prescribed for respiratory tract infections in Australia.
  
  
  OBJECTIVE
  The aim of this study was to describe the clinical predictors of GPs' prescribing of antibiotics.
  
  
  METHODS
  We used Clinical Judgment Analysis to study the responses of GPs to hypothetical paper-based vignettes of a 20-year-old with a respiratory tract infection. The nature of four symptoms and signs (colour of nasal mucous discharge; soreness of the throat; presence of fever; and whether any cough was productive of sputum) was varied and their effect on prescribing measured using logistic regression.
  
  
  RESULTS
  Twenty GPs participated. The nature of each symptom and sign significantly predicted prescribing of an antibiotic. Cough productive of yellow sputum; presence of sore throat; fever; and coloured nasal mucus increased the probability of an antibiotic being prescribed.
  
  
  CONCLUSIONS
  GPs are influenced by clinical signs and symptoms to use antibiotics for respiratory infections for which there is poor evidence of efficacy from the literature.
authors.affiliation: Centre for General Practice, University of Queensland Medical School, Herston, Queensland 4006, Australia.
authors.forename: S
authors.initials: S
authors.lastname: Murray
authors.forename: C
authors.initials: C
authors.lastname: Del Mar
authors.forename: P
authors.initials: P
authors.lastname: O'Rourke
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002983:Clinical Competence; D003371:Cough / Q000382:microbiology; D003661:Decision Support Techniques; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D004363:Drug Utilization; D005194:Family Practice / Q000458:organization & administration*; D005334:Fever / Q000382:microbiology; D006801:Humans; D007600:Judgment; D016015:Logistic Models; D010612:Pharyngitis / Q000382:microbiology; D010865:Pilot Projects; D010818:Practice Patterns, Physicians' / Q000458:organization & administration*; D011237:Predictive Value of Tests; D012044:Regression Analysis; D012141:Respiratory Tract Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D013183:Sputum / Q000382:microbiology; D011795:Surveys and Questionnaires
chemical_list: D000900:Anti-Bacterial Agents