title: The role of immune responses in bone loss during periodontal disease.
abstract: A network of cytokines and other soluble mediators unites the immune system and bone; bacterial infections induce immune responses which may perturb this network. Periodontal diseases are Gram-negative infections resulting in bone loss in the jaw. Evidence is presented that immune responses to these infections produces net resorption of bone.
authors.affiliation: Biology Department, Bates College, Lewistown, Maine 04240, USA.
authors.forename: P J
authors.initials: PJ
authors.lastname: Baker
mesh_terms: D016301:Alveolar Bone Loss / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D016723:Bone Remodeling; D016207:Cytokines / Q000378:metabolism; D006090:Gram-Negative Bacteria / Q000276:immunology / Q000378:metabolism; D016905:Gram-Negative Bacterial Infections / Q000150:complications / Q000276:immunology* / Q000473:pathology; D006801:Humans
chemical_list: D016207:Cytokines