[Testicular embryonal carcinoma with contralateral synchronous intratubular germ cell neoplasia: analysis of a case].
We report the case of a 20-year old male with a right testicular tumor. Bilateral orchidectomy was practised considering the synchronous clinical, ultrasonographical and histological (intraoperative biopsy) findings of the left testis. The definitive pathological report showed a right embryonal carcinoma with wide intratubular germ cell neoplasia (IGCN) of the contralateral testis. IGCN (formerly carcinoma in situ) is present in about 5% of cases in the contralateral gonad of those patients with a testicular neoplasm. More than 50% will develop cancer in that testis. Clinical and physical examination findings are usually unspecific. The diagnosis of IGCN is based on biopsy, although ultrasonography could give some data too, as some authors report. We analyze the therapy options for IGCN: (orchidectomy, chemotherapy, radiotherapy, or "wait and see"). In our case, the first one was made. Chemotherapy was used due to existence of retroperitoneal lymph node metastases, with an excellent follow-up afterwards.
Cruz Guerra
N A
NA
Servicio de Urología, Hospital Ramón y Cajal, Madrid.
Mayayo Dehesa
T
T
Cuesta Roca
C
C
Arias Fúnez
F
F
Sánchez Encinas
M
M
Escudero Barrilero
A
A
D018236:Carcinoma, Embryonal / Q000175:diagnosis / Q000628:therapy; D018237:Germinoma / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000628:therapy; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000628:therapy