[Gene therapy of chronic infections of the urogenital system using cytotoxic peptides].
Gene therapy of chronic infectious diseases of urogenital tract represents a new perspective field in the modern biological and medical sciences. In the review discuss one of the new directions in gene therapy of urogenital infections caused by Mycoplasma: inhibition of mycoplasmal infection after administration of recombinant plasmid vectors, expressed the genes of cytotoxic peptides.
Lazarev
V N
VN
Institute of Physico-Chemical Medicine, Russia, Moscow.
Govorun
V M
VM
Aleksandrova
N M
NM
Lopukhin
Iu M
IuM
D000942:Antigens, Bacterial / Q000235:genetics; D002908:Chronic Disease; D003603:Cytotoxins / Q000235:genetics* / Q000378:metabolism; D052776:Female Urogenital Diseases / Q000382:microbiology / Q000628:therapy*; D015316:Genetic Therapy; D005822:Genetic Vectors; D006801:Humans; D052801:Male Urogenital Diseases; D009175:Mycoplasma Infections / Q000628:therapy*; D010455:Peptides / Q000235:genetics* / Q000378:metabolism
D000942:Antigens, Bacterial; D003603:Cytotoxins; D010455:Peptides; C043431:M antigen, Brucella melitensis