title: In vivo uptake of azithromycin in human coronary plaques.
abstract: Ten patients with symptomatic coronary artery disease received oral azithromycin for 3 days and underwent directional atherectomy on the third day. Azithromycin was found in all plaque samples with a median concentration of 284 ng/ml (95% confidence interval 163 to 517 ng/ml).
authors.affiliation: Klinik III für Innere Medizin, Universität zu Köln, Germany. christian.schneider@medizin.uni-koeln.de
authors.forename: C A
authors.initials: CA
authors.lastname: Schneider
authors.forename: H
authors.initials: H
authors.lastname: Diedrichs
authors.forename: K D
authors.initials: KD
authors.lastname: Riedel
authors.forename: T
authors.initials: T
authors.lastname: Zimmermann
authors.forename: H W
authors.initials: HW
authors.lastname: Höpp
mesh_terms: D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics* / Q000627:therapeutic use; D017225:Atherectomy, Coronary; D017963:Azithromycin / Q000493:pharmacokinetics* / Q000627:therapeutic use; D016022:Case-Control Studies; D016993:Chlamydophila pneumoniae / Q000302:isolation & purification; D003327:Coronary Disease / Q000378:metabolism* / Q000382:microbiology / Q000628:therapy; D006801:Humans; D011446:Prospective Studies
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin