[Cytogenetic disorders iin patients with chronic hepatitis B and C].
The chromosomal apparatus of peripheral blood lymphocytes was studied in 19 patients with chronic hepatitis B (CHB) and 17 patients with chronic hepatitis C (CHC). Significant changes in cytogenetic indices were revealed in the both groups. Incidence of aberrant cells in CHC exceeded significantly that in CHB (15.3 +/- 1.5% vs 11.1 +/- 0.9% respectively; P < 0.05). Frequencies of aberration per cell and chromatid fragments were also significantly higher in CHC compared with both CHB and practically normal donor groups.
Bariliak
I R
IR
Frolov
V M
VM
Pinskiĭ
L L
LL
Topol'nitskiĭ
V S
VS
D002842:Chromatids / Q000235:genetics; D002869:Chromosome Aberrations / Q000235:genetics*; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D019694:Hepatitis B, Chronic / Q000235:genetics*; D019698:Hepatitis C, Chronic / Q000235:genetics*; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D008677:Metaphase / Q000235:genetics