title: Painful trigeminal neuropathy caused by severe mandibular resorption and nerve compression in a patient with systemic sclerosis: case report and literature review.
abstract: Systemic sclerosis is a multi-system disorder characterized by abundant fibrosis of the skin, blood vessels, and visceral organs. Although resorption of the mandible has been commonly observed and reported, we found no report of resorption leading to a painful neuropathy of the inferior alveolar nerve. We report a case of a patient with systemic sclerosis, severe resorption of the angles, and inferior alveolar border of the mandible, resulting in a compression neuropathy of the inferior alveolar nerve. Diagnostic tests, medical treatment, and surgical treatment are discussed, and the relevant literature is reviewed.
authors.affiliation: UMDNJ New Jersey Dental School, Division of Oral Medicine, Newark, NJ, USA.
authors.forename: D K
authors.initials: DK
authors.lastname: Fischoff
authors.forename: D
authors.initials: D
authors.lastname: Sirois
mesh_terms: D000085:Acetates / Q000627:therapeutic use; D000328:Adult; D000588:Amines; D000700:Analgesics / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D001862:Bone Resorption / Q000209:etiology; D017675:CREST Syndrome / Q000150:complications*; D003509:Cyclohexanecarboxylic Acids; D005260:Female; D000077206:Gabapentin; D006801:Humans; D008336:Mandibular Diseases / Q000150:complications* / Q000209:etiology*; D008340:Mandibular Nerve; D009408:Nerve Compression Syndromes / Q000150:complications / Q000209:etiology*; D014277:Trigeminal Neuralgia / Q000188:drug therapy / Q000209:etiology*; D005680:gamma-Aminobutyric Acid
chemical_list: D000085:Acetates; D000588:Amines; D000700:Analgesics; D000927:Anticonvulsants; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin