title: Using symmetry to monitor geared bond rotation in aromatic amides by dynamic NMR
abstract: Dynamic NMR proves that the fastest interconversion between conformers of simple tertiary aromatic amide 3 is racemization via a geared (correlated) rotation of both the Ar-CO and N-CO bonds. The symmetry of 3 is such that correlated and noncorrelated rotations are easily distinguishable, even without assignment of the NMR spectrum, simply by observing the number of peaks taking part in the exchange.
authors.affiliation: Department of Chemistry, University of Manchester, Oxford Road, Manchester M13 9PL, U.K.
authors.initials: RA
authors.lastname: Bragg
authors.initials: J
authors.lastname: Clayden