Abnormal neuronal ionic flux activity: learning paradigms of schizophrenic thought disorders.
New developments in biological psychiatry have prompted the development of our pathophysiological theory of the etiology of schizophrenic thought disorders. We suggest that the presence of brain bionic lesions may produce microneuropathies in certain neuronal electrical pathways, leading to abnormal biological communication. These blockages force the rerouting of incoming electric signals through bypass pathways which divert the message from target to non-target neurons for decoding and integration. Using this model, we were able to link specific schizophrenic disturbances to different types of brain bionic lesion effects. This model should be further investigated to facilitate the understanding of the nature and origin of schizophrenic disorders and to stimulate further interest in this fascinating field.
Naisberg
Y
Y
'Sha'ar Menashe Mental Health Center, Mobile Post, Hefer, Israel.
Modai
I
I
Weizman
A
A
D001921:Brain / Q000503:physiopathology*; D006801:Humans; D007858:Learning / Q000502:physiology*; D008959:Models, Neurological; D008960:Models, Psychological; D009474:Neurons / Q000502:physiology*; D012559:Schizophrenia / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D013850:Thinking / Q000502:physiology*