Chemokines and their receptors in allograft rejection.
Despite current recognition of over 40 chemokines and more than 18 chemokine receptors, understanding of their role in transplant immunobiology and transplant rejection is extremely limited and fragmentary. Recent literature has demonstrated the presence of chemokines and their receptors in transplants and some studies demonstrate important functional roles.
Hancock
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WW
Millennium Pharmaceuticals Incorparated, Cambridge, MA 02139, USA. whancock@mpi.com
Gao
W
W
Faia
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KL
Csizmadia
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V
D000818:Animals; D018925:Chemokines / Q000502:physiology*; D002634:Chemotaxis, Leukocyte; D006084:Graft Rejection; D006801:Humans; D016030:Kidney Transplantation; D009504:Neutrophils / Q000276:immunology; D019707:Receptors, Chemokine / Q000502:physiology*; D015427:Reperfusion Injury / Q000150:complications; D014184:Transplantation, Homologous
D018925:Chemokines; D019707:Receptors, Chemokine