title: Verbal processing deficits in schizophrenia.
abstract: The authors reported that a subgroup of schizophrenic patients performed well on a tone serial position task but was impaired on an auditory word serial position task (Wexler, Stevens, Bowers, Cerniak, & Goldman-Rakic, 1998). This study assessed 30 schizophrenic and 32 controls (matched for comparable tone discrimination) on 4 versions of the verbal serial position tasks and 2 tone serial position tasks. Patients performed poorly on all verbal tasks but performed comparably to controls when tones served as stimuli. Proactive interference and visual presentation further compounded the verbal deficits. Deficits persisted with pronounceable nonword stimuli. These findings provide evidence of specific deficits in language-related processing, although the authors could not rule out the possibility that the differential effects that were observed between the tone and word tasks, and particularly among the verbal tasks, may result from differing discriminating power of the different tests.
authors.affiliation: Department of Diagnostic Radiology, Yale University School of Medicine, USA. stevenal@ohsu.edu
authors.forename: A A
authors.initials: AA
authors.lastname: Stevens
authors.forename: N H
authors.initials: NH
authors.lastname: Donegan
authors.forename: M
authors.initials: M
authors.lastname: Anderson
authors.forename: P S
authors.initials: PS
authors.lastname: Goldman-Rakic
authors.forename: B E
authors.initials: BE
authors.lastname: Wexler
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall; D008875:Middle Aged; D012559:Schizophrenia / Q000175:diagnosis*; D012565:Schizophrenic Psychology; D012691:Serial Learning; D013067:Speech Perception; D014706:Verbal Learning