Tuberomammillary nucleus activation anticipates feeding under a restricted schedule in rats.
We used FOS-immunoreactivity to map changes in the neuronal activity of brain nuclei related to the state of arousal, in rats under a restricted feeding schedule. Our main finding was the outstanding activation of the tuberomammillary nucleus 24h after a meal, and its steep deactivation, which was independent of actually having the meal. The time course of FOS activation and deactivation indicated a burst of tuberomammilary nucleus activity in close temporal relation with the increased locomotor activity shown by rats in anticipation of the next meal.
Inzunza
O
O
Departamento de Anatomía, Facultad de Medicina, Pontificia Universidad Católica de Chile, Alameda 340, Santiago, Chile.
Serón-Ferré
M J
MJ
Bravo
H
H
Torrealba
F
F
D000818:Animals; D001143:Arousal / Q000502:physiology; D002940:Circadian Rhythm / Q000502:physiology; D005247:Feeding Behavior / Q000502:physiology; D005248:Feeding Methods; D007026:Hypothalamic Area, Lateral / Q000201:enzymology / Q000502:physiology*; D007150:Immunohistochemistry; D008297:Male; D009043:Motor Activity / Q000502:physiology; D017346:Protein Serine-Threonine Kinases / Q000032:analysis; D051381:Rats; D017207:Rats, Sprague-Dawley; D038744:Ribosomal Protein S6 Kinases, 90-kDa
D017346:Protein Serine-Threonine Kinases; D038744:Ribosomal Protein S6 Kinases, 90-kDa