title: [The use of controlled hypotonia in endonasal microsurgical interventions on the paranasal sinuses in patients with chronic rhinosinusitis].
abstract: The technique of controlled hypotonia was developed for adequate management of anesthesia in endonasal microsurgical interventions on the paranasal sinuses in patients with chronic rhinosinusitis. A total of 92 patients with chronic polypous rhinosinusitis aged 18 to 65 years were operated using the following variants of anesthesia: local, local in combination with neuroleptanalgesia and/or ataralgesia with controlled hypotonia, endotracheal oxide-fluoroxene and endotracheal oxide-oxygen anesthesias with neuroleptanalgesia and/or ataralgesia with controlled hypotonia. This was achieved with clofelin. Controlled hypotonia reduces blood loss in endonasal microsurgery on the paranasal sinuses in patients with chronic polypous rhinosinusitis compared to patients unexposed to controlled hypotonia.
authors.forename: G P
authors.initials: GP
authors.lastname: Zakharov
authors.forename: L V
authors.initials: LV
authors.lastname: Iurchenko
mesh_terms: D000293:Adolescent; D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000494:pharmacology*; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003000:Clonidine / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D008866:Microsurgery; D008875:Middle Aged; D009123:Muscle Hypotonia / Q000139:chemically induced*; D010256:Paranasal Sinuses / Q000187:drug effects* / Q000601:surgery*; D011127:Polyps / Q000601:surgery*; D012852:Sinusitis / Q000601:surgery*
chemical_list: D000316:Adrenergic alpha-Agonists; D003000:Clonidine