title: [Urinary tract infections--still a real problem].
abstract: By analyzing the standard works in the scientific world literature, it was possible to construct a contemporary view on the etiology and antibiotic therapy of some urinary tract infections. It can be stated, that the most effective remedies are cotrimoxazol and fluoroquinolones. In contrary to beta-lactam antibiotics, cotrimoxazole and fluoroquinolones work with a rapid bactericidal effect, they have long elimination half-times and better sterilization capacity in the periurethral region, and it use brings minimal risk of recurrence of the infection. This facts are compared with results of bacteriological investigation of urine, which were done in the microbiological laboratories of University Hospital Hradec Králové, Czech Republic, in 1998. The most frequent origins of urinary tract infections are Escherichia coli and Enterococcus spp. Stains. The are keeping high susceptibility to contrimoxazole, furantoin and oxoline acid. The other Gram negative rods isolated from hospitalised patients are highly resistant to most of antimicrobial agents included fluorochinolons, which resistance culminates to 50%. The widest spectrum of pathogens and the highest resistance was found in the hospitalised patients of the university hospital. High percentages of resistant strains was also in patients from the district hospitals. The results are discussed.
authors.affiliation: Ustav klinické mikrobiologie LF a UK, Hradec Králové.
authors.forename: P
authors.initials: P
authors.lastname: Cermák
authors.forename: Z
authors.initials: Z
authors.lastname: Veselský
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D006801:Humans; D014552:Urinary Tract Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents