Asperger's syndrome, X-linked mental retardation (MRX23), and chronic vocal tic disorder.
Pervasive developmental disorders are severe disorders of development with no consistent neurobiologic etiology and most often an idiopathic etiology. We report a 12-year-old male who met criteria for a pervasive developmental disorder (Asperger's syndrome) and a chronic tic disorder. The child also has an X-linked cognitive impairment (MRX23). The presence of tic symptomatology, pervasive developmental disorder, and fragile X syndrome has previously been reported. Since no singular etiology for Asperger's syndrome has been found, the possibility of other cases of Asperger's syndrome occurring with concurrent abnormalities on the X chromosome should be considered by clinicians, especially if tic symptomatology is present.
Searcy
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Child Evaluation and Treatment Program, Grand Forks, North Dakota 58202, USA.
Burd
L
L
Kerbeshian
J
J
Stenehjem
A
A
Franceschini
L A
LA
D020817:Asperger Syndrome / Q000150:complications*; D002648:Child; D002908:Chronic Disease; D003072:Cognition Disorders / Q000175:diagnosis; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications* / Q000235:genetics*; D009483:Neuropsychological Tests; D010375:Pedigree; D012720:Severity of Illness Index; D020323:Tics / Q000150:complications* / Q000503:physiopathology*; D014827:Vocal Cords / Q000503:physiopathology*; D014960:X Chromosome / Q000235:genetics*