title: [Ciprofibrate in the treatment of combined hyperlipoproteinemia. Results in more than 600 patients from 23 centers in the Czech Republic].
abstract: A total of 633 patients with combined hyperlipoproteinaemia from 23 centres in the Czech Republic met the criteria for assessment of the effectiveness of 3-month administration of 100 mg ciprofibrate (Lipanor) per day. The cholesterol concentration declined from the original values of 6.94 mmol/l by 13%. The drop of triglycerides was even more significant from 3.03 mmol/l by more than 41%. The relatively low HDL cholesterol at the beginning, 1.14 mmol/l, increased by 15%, while LDL-cholesterol dropped significantly by almost 12%. The classical atherogenic index expressed by the ratio of total/HDL cholesterol declined by 25%. Treatment was very well tolerated by the patients and was associated with a minimum of undesirable side-effects. Treatment with ciprofibrate is effective and safe treatment in patients with combined hyperlipoproteinaemia.
authors.affiliation: Za skupinu spolupracujících center Klinického sledování úcinnosti lipanoru III. interní klinika 1, Praha.
authors.forename: R
authors.initials: R
authors.lastname: Ceska
authors.forename: T
authors.initials: T
authors.lastname: Kvasnicka
authors.forename: T
authors.initials: T
authors.lastname: Haas
authors.forename: V
authors.initials: V
authors.lastname: Soska
authors.forename: H
authors.initials: H
authors.lastname: Vaverková
mesh_terms: D002995:Clofibric Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D005260:Female; D058607:Fibric Acids; D006801:Humans; D006951:Hyperlipoproteinemias / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
chemical_list: D058607:Fibric Acids; D000960:Hypolipidemic Agents; D002995:Clofibric Acid; C019304:ciprofibrate