Offspring sex ratio of subfertile men and men with abnormal sperm characteristics.
Previous work has suggested an association between male subfertility and a female-biased offspring sex ratio. This study of the reproduction of men who had a semen analysis at the Sperm Analysis Laboratory in Copenhagen in the period 1963-1993 showed that the subfertile men had an offspring sex ratio as expected (51.0% boys versus 51.3%, P: = 0.56), and within the cohort, the offspring sex ratio had no material association with particular semen characteristics. Our results thus suggest that no important association exists between general male subfertility and a female-biased offspring sex ratio.
Jacobsen
R
R
Department of Epidemiology, Institute of Public Health, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark. R.jacobsen@pubhealth.ku.dk
Bostofte
E
E
Skakkebaek
N E
NE
Hansen
J
J
Moller
H
H
D015331:Cohort Studies; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007248:Infertility, Male / Q000503:physiopathology*; D008297:Male; D012098:Reproduction; D012744:Sex Ratio; D013076:Sperm Count; D013094:Spermatozoa / Q000002:abnormalities*