title: Effects on gingivitis of two different 0.4% SnF2 gels.
abstract: For nine months we monitored the periodontal health of 81 adolescents undergoing orthodontic treatment with fixed appliances, to determine whether daily use of a brush-on 0.4% SnF2 gel would be better than toothbrushing alone in maintaining periodontal health in these patients, and whether a gel supplying a high percentage of available Sn2+ ion would be more beneficial than a gel supplying a low percentage of available Sn2+ ion. The subjects were matched for age and sex and placed into a control group, which used toothbrushing alone, and two treatment groups, which used toothbrushing supplemented with daily use of a SnF2 gel. One treatment group used a gel with 98% available Sn2+ ion twice daily for the entire nine months. The other treatment group used a gel with less than 2% available Sn2+ once a day for six months, then twice a day for the remaining three months of the study. Clinical assessments (Plaque Index, Gingival Index, Bleeding Tendency, pocket depth, and coronal staining) were made before appliances were placed and at one, three, six, and nine months after appliances were placed. Results indicated that the group using the high-availability Sn2+ gel twice daily had significantly lower Gingival Index and Bleeding Tendency scores at the one-, three-, six-, and nine-month examinations than did the control group. The group using the low-availability Sn2+ gel showed no significant differences in these assessments from the control group. Neither treatment group showed significant differences from the control group in Plaque Index or pocket depth. In the group using the high-availability Sn2+ gel, one subject developed mild coronal staining, and two developed moderate staining.
authors.affiliation: Department of Growth and Development, School of Dentistry, University of California at San Francisco 94143-0640, USA.
authors.forename: R L
authors.initials: RL
authors.lastname: Boyd
authors.forename: P J
authors.initials: PJ
authors.lastname: Leggott
authors.forename: P B
authors.initials: PB
authors.lastname: Robertson
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D002327:Cariostatic Agents / Q000008:administration & dosage*; D002648:Child; D003773:Dental Plaque / Q000209:etiology; D003774:Dental Plaque Index; D004311:Double-Blind Method; D005260:Female; D005460:Fluorides, Topical / Q000008:administration & dosage*; D005782:Gels; D005891:Gingivitis / Q000517:prevention & control*; D006801:Humans; D008297:Male; D015588:Observer Variation; D009967:Orthodontic Appliances / Q000009:adverse effects; D010349:Patient Compliance; D010512:Periodontal Index; D014002:Tin Fluorides / Q000008:administration & dosage*; D014099:Toothbrushing; D016896:Treatment Outcome
chemical_list: D002327:Cariostatic Agents; D005460:Fluorides, Topical; D005782:Gels; D014002:Tin Fluorides