title: Evaluation of behavioral disinhibition in P/NP and HAD1/LAD1 rats.
abstract: 1. Two lines of rats specifically bred for alcohol preference were exposed to two different behavioral tasks that required behavioral inhibition to successfully solve. 2. Learning and performance of a step-down passive avoidance task and a differential reinforcement of low-rate responding task were studied in P/NP and HAD1/LAD1 rats. 3. While the P rats had difficulty in learning both tasks, HAD1, LAD1 and NP rats performed at control levels. 4. These data suggest that P rats, but not HAD1 rats, may have problems learning tasks that require inhibition of ongoing or previously learned behaviors.
authors.affiliation: Department of Psychology, Indiana University, Bloomington 47405-7007, USA. steinmet@indiana.edu
authors.forename: J E
authors.initials: JE
authors.lastname: Steinmetz
authors.forename: M R
authors.initials: MR
authors.lastname: Blankenship
authors.forename: J T
authors.initials: JT
authors.lastname: Green
authors.forename: G B
authors.initials: GB
authors.lastname: Smith
authors.forename: P R
authors.initials: PR
authors.lastname: Finn
mesh_terms: D000818:Animals; D001362:Avoidance Learning; D001522:Behavior, Animal / Q000187:drug effects; D002492:Central Nervous System Depressants / Q000494:pharmacology*; D003216:Conditioning, Operant; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains / Q000235:genetics
chemical_list: D002492:Central Nervous System Depressants; D000431:Ethanol