[Citalopram (Cipramil) in monotherapy of depressed outpatients].
Citalopram at a dose of 20 mg was used as monotherapy in the treatment of 91 outpatients with depression mostly of moderate intensity. The duration of treatment was 2 months. Patients were assessed by Clinical Global Impression Scale (CGI) before, after 1st and 2nd months of therapy. Twenty three patients were additionally rated after 2 weeks. Observed and spontaneously adverse events were also recorded. A large proportion of treated patients (75%) showed full or almost full remission (1 or 2 on CGI) at the end of study. There were only few mainly mild adverse events during treatment. Nausea (7.7%) and headache (3.3%) occurred most often. The author conclude that citalopram is a well-tolerated and efficacious antidepressant drug for outpatients.
Landowski
J
J
I Klinika Chorób Psychicznych, Akademia Medyczna, Gdańsk.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000553:Ambulatory Care; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects / Q000627:therapeutic use*; D015283:Citalopram / Q000009:adverse effects / Q000627:therapeutic use*; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000534:rehabilitation*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index
D018687:Antidepressive Agents, Second-Generation; D015283:Citalopram