Postoperative nausea and vomiting after sevoflurane with or without ondansetron compared with propofol in female patients undergoing breast surgery.
We studied 180 female patients undergoing breast surgery. The patients were randomly allocated to receive one of three anesthetic techniques. Compared with either propofol or sevoflurane alone, sevoflurane with ondansetron resulted in a decreased incidence of postoperative nausea and vomiting. Sevoflurane with ondansetron prophylaxis is a good alternative to propofol with respect to avoiding postoperative nausea and vomiting.
Jokela
R M
RM
Department of Anesthesia, Lapland Central Hospital, Rovaniemi, Finland. Ritva.M.Jokela@hus.fi
Kangas-Saarela
T A
TA
Valanne
J V
JV
Koivuranta
M K
MK
Ranta
P O
PO
Alahuhta
S M
SM
D018685:Anesthetics, Inhalation / Q000008:administration & dosage* / Q000009:adverse effects; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D000932:Antiemetics / Q000008:administration & dosage*; D001940:Breast / Q000601:surgery*; D005260:Female; D006801:Humans; D008738:Methyl Ethers / Q000008:administration & dosage* / Q000009:adverse effects; D008875:Middle Aged; D017294:Ondansetron / Q000008:administration & dosage*; D020250:Postoperative Nausea and Vomiting / Q000517:prevention & control*; D015742:Propofol / Q000008:administration & dosage*; D000077149:Sevoflurane
D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D000932:Antiemetics; D008738:Methyl Ethers; D000077149:Sevoflurane; D017294:Ondansetron; D015742:Propofol