title: Sociopathy, gender, and treatment outcome among outpatient substance abusers.
abstract: Antisocial personality disorder (ASPD) may predict poor prognosis but gender/sociopathy relationships to prognosis remain unclear. This study investigated the effects of ASPD upon psychiatric and substance-related outcomes among 235 addiction treatment center outpatients. Prevalence rates for ASPD were similar for males (16%) and females (22%). At baseline, women and ASPD patients displayed greater substance-related and psychiatric severity. At 6-month follow-up, ASPD patients had greater severity on both measures than did patients without ASPD, but women now had equivalent psychiatric severity to men. After controlling for initial severity, ASPD was related to worse substance-related outcomes, but not to worse psychiatric outcomes.
authors.affiliation: Department of Psychiatry and Alcohol Research Center, University of Michigan, Ann Arbor, MI 48108-3318, USA. galenl@gvsu.edu
authors.forename: L W
authors.initials: LW
authors.lastname: Galen
authors.forename: K J
authors.initials: KJ
authors.lastname: Brower
authors.forename: B W
authors.initials: BW
authors.lastname: Gillespie
authors.forename: R A
authors.initials: RA
authors.lastname: Zucker
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D000987:Antisocial Personality Disorder / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012720:Severity of Illness Index; D019966:Substance-Related Disorders / Q000150:complications / Q000534:rehabilitation*; D016896:Treatment Outcome