Birth of rhesus monkey infant after transfer of embryos derived from in-vitro matured oocytes: short communication.
Although strategies for in-vitro maturation of oocytes from rodents and domestic species have been relatively successful, application of these techniques to primates has not met with similar success. Currently, evaluation of the developmental capacity of oocytes following fertilization is the only reliable means to assess cytoplasmic maturation. Although rhesus monkey blastocysts have previously been produced from in-vitro matured oocytes, full developmental competence has not been demonstrated by term development. Here we report the birth of the first non-human primate infant derived from in-vitro matured oocytes.
Schramm
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RD
Wisconsin Regional Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA. schramm@primate.wisc.edu
Paprocki
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AM
D000818:Animals; D000831:Animals, Newborn; D002478:Cells, Cultured; D016922:Cellular Senescence; D006063:Chorionic Gonadotropin / Q000378:metabolism; D006224:Cricetinae; D004624:Embryo Transfer; D005260:Female; D007743:Labor, Obstetric; D008253:Macaca mulatta / Q000502:physiology*; D008297:Male; D009865:Oocytes / Q000502:physiology*; D011247:Pregnancy; D016216:Ultrasonography, Prenatal
D006063:Chorionic Gonadotropin