title: Price, cost and value of opiate detoxification treatments. Reanalysis of data from two randomised trials.
abstract: BACKGROUND
  Treatments in different settings have different costs. A dilemma arises if expensive treatments lead to better outcomes.
  
  
  OBJECTIVE
  To investigate conflicts between the priorities of cost minimisation, clinical effectiveness, and cost-effectiveness in the detoxification of opiate addicts.
  
  
  METHODS
  Cost and clinical effectiveness were examined using published outcome data. The main outcome measures were: achieving a drug-free state on completion of detoxification; the economic costs of treatment.
  
  
  RESULTS
  In terms of simple cost, in-patient detoxification is much more expensive than out-patient treatment (ratio, 24:1). With adjustment for successful outcome, the costs are almost identical (ratio, 0.9:1). Comparison of specialist and general psychiatry in-patient settings showed that even when adjusted for clinical outcomes, the specialist setting is more costly (ratio, 1.9:1), although the outcomes are better.
  
  
  CONCLUSIONS
  Naïve adherence to cost and cost-containment considerations is dangerous. Discussion of treatment costs is misleading if not informed by, and adjusted for, evidence of effectiveness. This is especially important where marked differences in outcome between treatment options exist.
authors.affiliation: National Addiction Centre, London, UK.
authors.forename: M
authors.initials: M
authors.lastname: Gossop
authors.forename: J
authors.initials: J
authors.lastname: Strang
mesh_terms: D000553:Ambulatory Care / Q000191:economics; D003362:Cost-Benefit Analysis; D003365:Costs and Cost Analysis; D003627:Data Interpretation, Statistical; D006760:Hospitalization / Q000191:economics; D006801:Humans; D009293:Opioid-Related Disorders / Q000191:economics* / Q000628:therapy; D016896:Treatment Outcome