Mullerian adenosarcoma of the uterus associated with tamoxifen therapy.
Mullerian adenosarcoma of the uterus is a biphasic tumor exhibiting benign epithelial and malignant stromal component. This tumor may occasionally be associated with tamoxifen therapy which is used as an adjuvant drug for breast carcinoma. Reviewing the literature, we found only 12 adenosarcoma cases associated with tamoxifen therapy Thus, the clinical and pathological findings in a 58 years old postmenopausal woman who developed uterine adenosarcoma, following low dose tamoxifen therapy after 8 years, was discussed in this report.
Arici
D S
DS
Department of Pathology, Cumhuriyet Universitesi Tip Fakültesi, Sivas, Türkiye. kemalarici@hotmail.com
Aker
H
H
Yildiz
E
E
Tasyurt
A
A
D018195:Adenosarcoma / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D001943:Breast Neoplasms / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000628:therapy; D004965:Estrogen Antagonists / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause; D013629:Tamoxifen / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D014594:Uterine Neoplasms / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery
D004965:Estrogen Antagonists; D013629:Tamoxifen