Reactivity of 3-iodoimidazo[1,2-a]pyridines using a Suzuki-type cross-coupling reaction.
The influence of base and solvent in Suzuki cross-coupling reaction on various 2-substituted-3-iodoimidazo[1,2-a]pyridines was reported. The reactivity was largely influenced by nature of the substituent. Optimized yields and shortened times of reaction were obtained using strong bases in DME.
Enguehard
C
C
Laboratoire de Chimie Thérapeutique, UFR des Sciences Pharmaceutiques, Tours, France.
Renou
J L
JL
Collot
V
V
Hervet
M
M
Rault
S
S
Gueiffier
A
A
D001897:Boronic Acids / Q000737:chemistry; D016861:Cyclooxygenase Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry
D001897:Boronic Acids; D016861:Cyclooxygenase Inhibitors; D011725:Pyridines