title: FT-IR spectroscopy utilization to sportsmen fatigability evaluation and control.
abstract: OBJECTIVE
  A longitudinal biological study of 20 elite rowers was performed using capillary blood (serum) FT-IR spectra to evaluate their training load adaptations and fatigue.
  
  
  METHODS
  Difference spectra (rest serum spectra subtracted to exercise serum spectra) were used to evaluate subjects' metabolic response to exercise. Spectra classifications were used for serum contents differentiation on the basis of biomolecular absorption.
  
  
  RESULTS
  For two subjects, several metabolic differentiations were observed. These started with sugars metabolism on the fifth training week, followed successively by lipid metabolism and protein metabolism, when overtraining was clinically diagnosed. Several weeks further into the training program, the same onset of metabolic differentiations was observed for eight other subjects. When differentiations reached lipid metabolism, they were asked to reduce their training loads. Unlike the overtrained subjects, a rapid recovery was observed (3 vs 22 wk) and metabolism alterations disappeared.
  
  
  CONCLUSIONS
  The fatigability limit in sportsmen seemed to be situated at a certain level of metabolic stress, beyond which a rapid overtraining process recover was no longer possible.
authors.affiliation: INSERM U443, Equipe de Chimie Bio-Organique, Université Victor Segalen Bordeaux 2, France.
authors.forename: C
authors.initials: C
authors.lastname: Petibois
authors.forename: G
authors.initials: G
authors.lastname: Cazorla
authors.forename: G
authors.initials: G
authors.lastname: Déléris
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D005080:Exercise Test; D017079:Exercise Tolerance / Q000502:physiology*; D005221:Fatigue / Q000097:blood*; D005227:Fatty Acids / Q000097:blood; D006801:Humans; D008055:Lipids / Q000097:blood; D008137:Longitudinal Studies; D010455:Peptides / Q000097:blood; D017550:Spectroscopy, Fourier Transform Infrared / Q000295:instrumentation*; D013177:Sports
chemical_list: D001786:Blood Glucose; D005227:Fatty Acids; D008055:Lipids; D010455:Peptides