title: Use of herbal therapies by adults seen in an ambulatory care research setting: an exploratory survey.
abstract: OBJECTIVE
  To identify and characterize patterns of use of herbal products among patients participating in selected research clinics.
  
  
  METHODS
  Survey of three National Institutes of Health (NIH) ambulatory care research clinics.
  
  
  METHODS
  Convenience sample of 490 adult patients (168 male, 322 female) attending rheumatology, liver, and endocrinology/metabolic research clinics.
  
  
  RESULTS
  Of the patients surveyed, 16.7%: (n = 82) reported using herbs. There were no significant sociodemographic differences between herb and nonherb users. Indications for herb use differed among the disease groups; patients in the endocrine and rheumatology clinics were taking herbs predominantly for "energy" or "wellness"; those attending the liver clinic tended to use herbal therapies as treatment for their disease. Mean and median monthly expenditure for herbal products was $30 and $10, respectively. There was a significant positive correlation between number of herbs used and use of other dietary supplements (p < 0.0001).
  
  
  CONCLUSIONS
  One in six patients in ambulatory clinical research settings may be taking herbal products in addition to prescribed treatment. This figure is lower than in the general population, possibly because the patients may stop using herbs when participating in a research project. Although empirical evidence on the beneficial or adverse effects of herb therapy alone or in combination with drug therapies is limited, clinical researchers should be aware of the potential for confounding clinical trial results.
authors.affiliation: Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892-1863, USA. johnsone@intra.nei.nih.gov
authors.forename: E M
authors.initials: EM
authors.lastname: Johnson
authors.forename: J C
authors.initials: JC
authors.lastname: Wootton
authors.forename: R
authors.initials: R
authors.lastname: Kimzey
authors.forename: L
authors.initials: L
authors.lastname: McCullagh
authors.forename: R
authors.initials: R
authors.lastname: Wesley
authors.forename: D C
authors.initials: DC
authors.lastname: Byrd
authors.forename: K K
authors.initials: KK
authors.lastname: Singh
authors.forename: D
authors.initials: D
authors.lastname: Rubino
authors.forename: F
authors.initials: F
authors.lastname: Pucino
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000553:Ambulatory Care; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009316:National Institutes of Health (U.S.); D008517:Phytotherapy; D010946:Plants, Medicinal; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology