Isolation and characterization of bioactive metabolites from marine-derived filamentous fungi collected from tropical and sub-tropical coral reefs.
Two new compounds, paecilospirone (1) and phomopsidin (2), and seven known compounds, chaetoglobosin A (3), griseofulvin (4), fusarielin A (5), fusapyrone (6), deoxyfusapyrone (7), and verrucarins J (8) and L acetate (9), have been isolated and characterized from marine-derived fungi collected in tropical and sub-tropical coral reef environments. The utility of marine-derived fungi as a source of bioactive secondary metabolites is discussed.
Namikoshi
M
M
Department of Ocean Sciences, Tokyo University of Fisheries, Japan. namikosh@tokyo-u-fish.ac.jp
Kobayashi
H
H
Yoshimoto
T
T
Meguro
S
S
Akano
K
K
D000818:Animals; D001685:Biological Factors / Q000737:chemistry / Q000302:isolation & purification*; D003063:Cnidaria / Q000382:microbiology*; D005658:Fungi / Q000737:chemistry*; D008386:Marine Biology; D015394:Molecular Structure; D013057:Spectrum Analysis; D014329:Tropical Climate
D001685:Biological Factors