Temporalis exteroceptive suppression in generalized anxiety disorder and major depression.
The duration abnormality of the exteroceptive suppressions, or silent periods, of peripheral or jaw-closing muscle activities induced by transcranial magnetic or trigeminal electrical stimuli in patients suffering from anxiety or depression is ill-defined. We therefore studied the exteroceptive suppression periods of the temporalis muscle electromyography elicited by trigeminal territory electrical stimuli, Zuckerman-Kuhlman's Personality Questionnaire, and Plutchik-van Praag's Depression Inventory (PVP) in 12 patients suffering from generalized anxiety disorder (GAD) and 16 from major depression (MD) as well as in 17 healthy volunteers. Durations of the second suppression period (ES2) sociability scores were decreased in GAD patients, while PVP and neuroticism-anxiety scores were elevated in both GAD and MD patients. There was a positive correlation between ES2 duration and sociability score in the GAD group. This study indicates that anxiety can modify the temporalis ES2 duration through cortical descending inhibitory controls.
Wang
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Anhui Institute of Stereotactic Neurosurgery and Anhui Provincial Hospital, Hefei, 230001, Anhui, PR China. wang_wei@mail.hf.ah.cn
Fu
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Wang
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D000293:Adolescent; D000328:Adult; D001008:Anxiety Disorders / Q000175:diagnosis / Q000503:physiopathology*; D001143:Arousal / Q000502:physiology*; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000503:physiopathology*; D004558:Electric Stimulation; D004576:Electromyography; D005260:Female; D006801:Humans; D007395:Interneurons / Q000502:physiology; D008297:Male; D009433:Neural Inhibition / Q000502:physiology*; D009434:Neural Pathways / Q000503:physiopathology; D010555:Personality Inventory; D013703:Temporal Muscle / Q000294:innervation*; D014276:Trigeminal Nerve / Q000503:physiopathology; D014279:Trigeminal Nucleus, Spinal / Q000503:physiopathology