title: Gastrointestinal stromal tumors of the small intestine that expressed c-kit protein.
abstract: We report two patients with gastrointestinal stromal tumors (GISTs) of the small intestine that expressed c-kit protein (CD117). One was a 68-year-old woman with epigastralgia and vomiting. A submucosal tumor of the upper jejunum was detected, and partial resection was carried out. The histology revealed a GIST negative for CD34 but positive for CD117. The other was a 42-year-old woman with progressive anemia, melena and lower abdominal pain. Intussusception was detected, and a partial resection was carried out. A submucosal tumor of the lower jejunum was noted. The histology revealed a GIST positive for both CD34 and CD117.
authors.affiliation: Department of Internal Mecidine, JA Suzuka Hospital, Mie.
authors.forename: N
authors.initials: N
authors.lastname: Hoshino
authors.forename: T
authors.initials: T
authors.lastname: Murata
authors.forename: K
authors.initials: K
authors.lastname: Oka
authors.forename: K
authors.initials: K
authors.lastname: Kawakami
authors.forename: K
authors.initials: K
authors.lastname: Hoshino
authors.forename: S
authors.initials: S
authors.lastname: Sekoguchi
authors.forename: T
authors.initials: T
authors.lastname: Suga
authors.forename: A
authors.initials: A
authors.lastname: Nishimura
authors.forename: M
authors.initials: M
authors.lastname: Kato
authors.forename: M
authors.initials: M
authors.lastname: Hamada
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007580:Jejunal Neoplasms / Q000175:diagnosis / Q000235:genetics*; D008637:Mesenchymoma / Q000175:diagnosis / Q000235:genetics*; D019009:Proto-Oncogene Proteins c-kit / Q000096:biosynthesis*
chemical_list: D019009:Proto-Oncogene Proteins c-kit