title: [Pathological fracture in primary malignant bone tumors].
abstract: Retrospective analysis of 30 patients with pathological fracture out of 336 patients with primary malignant bone tumors should demonstrate the influence a pathologic fracture and the form of surgical therapy have on the survival rate. In 25 out of 30 patients a fracture led to diagnosis of the disease. Pathological fractures occurred cumulatively by malignant fibrous histiocytoma of the bone and in tumor stages IIb and III. Surgery was performed on 26 out of 30 patients (12 ablative therapies, 14 reconstructive therapies). The mortality risk for patients with pathological fractures was more than double the risk for patients without pathological fractures (P = 0.0062). When performed correctly, reconstructive therapy does not influence the survival rate.
authors.affiliation: Stifung Orthopädische Universitätsklinik Heidelberg.
authors.forename: F
authors.initials: F
authors.lastname: Zeifang
authors.forename: D
authors.initials: D
authors.lastname: Sabo
authors.forename: V
authors.initials: V
authors.lastname: Ewerbeck
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical; D001859:Bone Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002648:Child; D002813:Chondrosarcoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005260:Female; D005354:Fibrosarcoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005598:Fractures, Spontaneous / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018219:Histiocytoma, Benign Fibrous / Q000401:mortality / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012516:Osteosarcoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D012086:Reoperation; D012512:Sarcoma, Ewing / Q000401:mortality / Q000473:pathology / Q000601:surgery; D015996:Survival Rate