title: Does muscle function and metabolism affect exercise performance in the heat?
abstract: It has been suggested that exercise performance in the heat is limited by the degree of hyperthermia, which, in some circumstances, compromises cardiovascular function and/or the central nervous system. However, this review presents evidence that a temperature-induced dysfunction to skeletal muscle contraction may contribute to a reduction in performance during exercise in the heat.
authors.affiliation: Department of Physiology, University of Melbourne, Parkville, Victoria, Australia. m.febbraio@physiology.unimelb.edu.au
authors.forename: M A
authors.initials: MA
authors.lastname: Febbraio
mesh_terms: D000818:Animals; D001831:Body Temperature; D001833:Body Temperature Regulation / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D005221:Fatigue / Q000209:etiology; D006003:Glycogen / Q000378:metabolism; D006360:Heat-Shock Proteins / Q000378:metabolism; D006358:Hot Temperature; D006801:Humans; D066298:In Vitro Techniques; D008931:Mitochondria, Muscle / Q000378:metabolism; D009119:Muscle Contraction / Q000502:physiology; D018482:Muscle, Skeletal / Q000378:metabolism / Q000502:physiology*; D010085:Oxidative Phosphorylation; D011817:Rabbits; D051381:Rats; D012146:Rest; D013997:Time Factors
chemical_list: D006360:Heat-Shock Proteins; D006003:Glycogen