Antiulcer effectiveness of Maytenus aquifolium spray dried extract.
The antiulcer activity of Maytenus aquifolium spray dried extract was studied in rats. Ulcers were induced by means of three experimental models: acidified-ethanol, indomethacin and acute stress. The extract was found to have significant antiulcer activity against all the models studied. These results show that preparation of the extract by means of the spray dried technique does not alter the biological activity of Maytenus aquifolium.
Bersani-Amado
C A
CA
Departamento de Farmácia e Farmacologia da Universidade Estadual de Maringá, Pr., Brazil.
Massao
L B
LB
Baggio
S R
SR
Johanson
L
L
Albiero
A L
AL
Kimura
E
E
D000818:Animals; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D004195:Disease Models, Animal; D000431:Ethanol / Q000633:toxicity; D007213:Indomethacin / Q000633:toxicity; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D018515:Plant Leaves / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D019685:Rosales / Q000627:therapeutic use*; D013276:Stomach Ulcer / Q000517:prevention & control*; D013312:Stress, Physiological
D000897:Anti-Ulcer Agents; D010936:Plant Extracts; D000431:Ethanol; D007213:Indomethacin