Cytotoxic activity of Agave intermixta L. (Agavaceae) and Cissus sicyoides L. (Vitaceae).
The cytostatic activities of Agave intermixta L. (Agavaceae) and Cissus sicyoides L. (Vitaceae) have been determined. In the antimitotic assay, Agave intermixta L. showed complete inhibition of cell division at 24 h of treatment. Both species showed a moderate cytostatic activity against HEp-2 cells, Cissus sicyoides L. being the most active species.
Sáenz
M T
MT
Laboratory of Pharmacognosy, Faculty of Pharmacy, University of Seville, s/n, 41012 - Seville, Spain. saenz@fafar.us.es
Garcia
M D
MD
Quilez
A
A
Ahumada
M C
MC
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001156:Artemia / Q000187:drug effects; D017691:Caribbean Region; D016923:Cell Death / Q000187:drug effects; D022781:Hepatocytes / Q000187:drug effects; D006801:Humans; D008519:Medicine, Traditional; D008938:Mitosis / Q000187:drug effects*; D008940:Mitotic Index; D010936:Plant Extracts / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D018517:Plant Roots / Q000166:cytology; D010946:Plants, Medicinal
D000970:Antineoplastic Agents; D010936:Plant Extracts