title: Catheter-based ultrasound thrombolysis--a new promising thrombus-debulking device for the treatment of intracoronary thrombosis.
abstract: Angiographic suggestion of intercoronary thrombus is often seen in patients sustaining acute coronary syndromes (ACS). Even in the era of stenting and glycoprotein IIb/IIIa antagonists, the presence of thrombus-rich lesion during percutaneous coronary interventions portends an increased risk of adverse events. It has been hypothesized that reduction of clot-burden prior to PCI may reduce complications and enhance efficacy. Experimental and clinical data have shown that catheter-based ultrasound thrombolysis is capable of inducing an efficacious and safe thrombus-debulking. This article reviews the collective experience with this promising device solution for the treatment of thrombotic lesions in the setting of ACS.
authors.affiliation: Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Brosh
authors.forename: U
authors.initials: U
authors.lastname: Rosenschein
mesh_terms: D006328:Cardiac Catheterization; D003328:Coronary Thrombosis / Q000601:surgery*; D006083:Graft Occlusion, Vascular / Q000601:surgery*; D006801:Humans; D009204:Myocardial Revascularization / Q000295:instrumentation / Q000379:methods*; D012501:Saphenous Vein / Q000637:transplantation; D017131:Thrombectomy / Q000295:instrumentation / Q000379:methods*; D014465:Ultrasonics