Lack of TP53 mutations in a case of porokeratosis palmaris, plantaris et disseminata.
A 73-year-old man with porokeratosis palmaris, plantaris et disseminata is presented. He had punctate, guttate and annular hyperkeratotic papular lesions widespread on his body with thorn-like hyperkeratosis on the palms and soles. Lesional skin did not show mutations of TP53 exons 5-6, 7, 8.
Ozkan
S
S
Department of Dermatology, Faculty of Medicine, University of Dokuz Eylül, Izmir, Turkey.
Fetil
E
E
Aydoğan
T
T
Atabey
N
N
Erkizan
V
V
Pabuçcuoğlu
U
U
Güneş
A T
AT
D000293:Adolescent; D000368:Aged; D004247:DNA / Q000235:genetics; D005192:Family Health; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation; D010375:Pedigree; D018807:Polymorphism, Single-Stranded Conformational; D017499:Porokeratosis / Q000235:genetics / Q000473:pathology*; D014407:Tumor Cells, Cultured; D016159:Tumor Suppressor Protein p53 / Q000235:genetics*
D016159:Tumor Suppressor Protein p53; D004247:DNA