[Arterial plasma nitric oxide and lactate level in hemorrhagic shock patients].
OBJECTIVE
To investigate the relationship between arterial plasma nitric oxide(NO), lactate (LA) concentration and prognosis of hemorrhagic shock patients.


METHODS
The blood levels of a NO and LA were measured with fluoropholometry and colorimetry in 48 hemorrhagic shock patients, and other 30 patients for selective surgery served as controls.


RESULTS
NO level was significantly lower and LA level was significantly higher in the hemorrhagic shock group than that of the control group respectively. NO level had a negative correlation with LA level and trauma index. NO level in the patients complicated by sepsis was still lower than that of the control group.


CONCLUSIONS
Decrease of NO level may be a main cause of disturbance of microcirculation and increase of LA. The lower the NO level, the higher the LA level, the worse the prognosis. So NO and LA level play an important role in forecasting progress of hemorrhagic shock patients.
Pei
L
L
Department of Anesthesiology, First Affiliated Hospital, China Medical University, Shenyang.
Wang
J
J
Xu
G
G
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D019344:Lactic Acid / Q000097:blood*; D008297:Male; D009569:Nitric Oxide / Q000097:blood*; D011379:Prognosis; D012771:Shock, Hemorrhagic / Q000097:blood*
D009569:Nitric Oxide; D019344:Lactic Acid