Inflammatory arthritis in children with osteochondrodysplasias.
Osteochondrodysplasias are a heterogeneous group of genetic skeletal dysplasias. Patients with these diseases commonly develop an early degenerative arthritis or osteoarthritis. Occasional observations of inflammatory arthritis have been made in this population but such observations are based on clinical grounds alone without confirmatory imaging studies. Four patients followed up in a paediatric rheumatology clinic with three different skeletal dysplasias, who had both clinical and radiological evidence of an inflammatory arthritis and coexistent degenerative arthritis, are described.
Scuccimarri
R
R
Division of Rheumatology, Montreal Children's Hospital, Montreal, Quebec, Canada.
Azouz
E M
EM
Duffy
K N
KN
Fassier
F
F
Duffy
C M
CM
D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D002648:Child; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D010003:Osteoarthritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D010009:Osteochondrodysplasias / Q000150:complications* / Q000175:diagnosis; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D018501:Antirheumatic Agents; D003287:Contrast Media; D008727:Methotrexate