Distribution of non-monosynaptic excitation to early and late recruited units in human forearm muscles.
The distribution of monosynaptic and nonmonosynaptic excitation was investigated within flexor carpi radialis (FCR) and extensor carpi radialis (ECR) motoneurone (MN) pools. FCR H reflexes of different size were conditioned by various conditioning stimuli eliciting different effects: (1) musculocutaneous-induced non-monosynaptic excitation of FCR MNs at the onset of biceps contraction, (2) heteronymous monosynaptic Ia facilitation, (3) reciprocal Ia inhibition, and (4) presynaptic inhibition of Ia terminals. Musculocutaneous-induced non-monosynaptic excitation increased continuously with the size of the unconditioned reflex. In contrast, heteronymous monosynaptic Ia excitation first increased and then decreased, with increases in the unconditioned reflex size, reciprocal inhibition and presynaptic inhibition showing an approximately similar tendency. This suggests that the non-monosynaptic excitation is distributed more evenly to early and late recruited MNs than monosynaptic Ia excitation, reciprocal inhibition and presynaptic inhibition. A different pattern of homonymous radial-induced monosynaptic and non-monosynaptic excitation was also found for individual ECR MNs investigated with the poststimulus time histogram (PSTH) method. Whereas the monosynaptic Ia excitation tended to be most marked in lower threshold MUs, the nonmonosynaptic excitation was evenly distributed to lower and higher threshold MUs. We propose that the even distribution of the non-monosynaptic excitation in the motoneuronal pool may be of significance when it is necessary to activate a wide range of MNs more or less simultaneously.
Marchand-Pauvert
V
V
Neurophysiologie Clinique, Rééducation, Hôpital de la Salpétrière, Paris, France.
Mazevet
D
D
Nielsen
J
J
Petersen
N
N
Pierrot-Deseilligny
E
E
D000200:Action Potentials / Q000502:physiology; D002574:Cervical Vertebrae; D004576:Electromyography; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology; D005542:Forearm / Q000033:anatomy & histology / Q000294:innervation / Q000502:physiology*; D006181:H-Reflex / Q000502:physiology; D006801:Humans; D009044:Motor Cortex / Q000166:cytology / Q000502:physiology; D009046:Motor Neurons / Q000166:cytology / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology; D018482:Muscle, Skeletal / Q000033:anatomy & histology / Q000294:innervation / Q000502:physiology*; D011712:Pyramidal Tracts / Q000166:cytology / Q000502:physiology*; D013116:Spinal Cord / Q000166:cytology / Q000502:physiology*; D013569:Synapses / Q000502:physiology / Q000648:ultrastructure; D009435:Synaptic Transmission / Q000502:physiology*; D013997:Time Factors