title: Immunoprophylactic effect of chicken egg yolk immunoglobulin (Ig Y) against porcine epidemic diarrhea virus (PEDV) in piglets.
abstract: Porcine epidemic diarrhea virus (PEDV) is the causative agent of neonatal diarrhea in piglets, which causes high mortality rates. In this study, the immunoprophylactic effects of chicken egg yolk immunoglobulin (Ig Y) against PEDV were investigated in neonatal pigs. Ig Y was found to reduce the mortality in piglets after challenge exposures. The field application of Ig Y also revealed significant differences in survival rates of piglets given Ig Y, as compared with placebo or control. The results in this study indicated that Ig Y against PEDV could be an alternative way of supplementing prophylactic measures like colostral antibodies from sows.
authors.affiliation: National Veterinary Research and Quarantine Service, Ministry of Agriculture and Forestry, Anyang, Korea.
authors.forename: C H
authors.initials: CH
authors.lastname: Kweon
authors.forename: B J
authors.initials: BJ
authors.lastname: Kwon
authors.forename: S R
authors.initials: SR
authors.lastname: Woo
authors.forename: J M
authors.initials: JM
authors.lastname: Kim
authors.forename: G H
authors.initials: GH
authors.lastname: Woo
authors.forename: D H
authors.initials: DH
authors.lastname: Son
authors.forename: W
authors.initials: W
authors.lastname: Hur
authors.forename: Y S
authors.initials: YS
authors.lastname: Lee
mesh_terms: D000818:Animals; D002522:Chlorocebus aethiops; D018352:Coronavirus Infections / Q000517:prevention & control / Q000662:veterinary*; D003967:Diarrhea / Q000517:prevention & control / Q000662:veterinary* / Q000821:virology; D004530:Egg Yolk / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D007136:Immunoglobulins / Q000627:therapeutic use*; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D014611:Vaccination / Q000662:veterinary*; D014709:Vero Cells
chemical_list: C016512:IgY; D007136:Immunoglobulins