Modern approaches to photoprotection.
UV light reacts with skin to produce undesirable changes, including photoaging and skin cancer. Sunscreen strategies are useful for protection against UV-B and short-wave UV-A, but complete protection against long-wave UV-A has not been achieved. Because UV-A is especially efficient at generating reactive oxygen species, it is being recognized increasingly as an important cause of photoaging and skin cancer.
DeBuys
H V
HV
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.
Levy
S B
SB
Murray
J C
JC
Madey
D L
DL
Pinnell
S R
SR
D000975:Antioxidants / Q000627:therapeutic use; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000517:prevention & control; D010126:Ozone / Q000009:adverse effects; D010787:Photosensitivity Disorders / Q000517:prevention & control; D015595:Skin Aging / Q000187:drug effects* / Q000528:radiation effects; D012878:Skin Neoplasms / Q000517:prevention & control; D013473:Sunscreening Agents / Q000627:therapeutic use*; D014466:Ultraviolet Rays / Q000009:adverse effects
D000975:Antioxidants; D013473:Sunscreening Agents; D010126:Ozone