title: [Biomaterials in urology].
abstract: Biomaterials are defined as non-living materials which are used in interaction with biological systems. Especially in the field of urology, biomaterials are applied in urinary diversion, urinary incontinence, erectile dysfunction, and as cosmetic prostheses. Biomaterial-tissue interaction is caused by the physical and chemical characteristics of the biomaterial, its degradation, and the resulting protein denaturation. General requirements include biocompatibility and functionality and the avoidance of carcinogenic, mutagenic, toxic, and allergic reactions. This is most important when there is permanent contact between urine and epithelial tissue, which may lead to biofilminfection and incrustation. Continuous modification of known materials, inauguration of new materials, as well as the possibilities of tissue engineering will determine their development in the years to come.
authors.affiliation: Urologische Klinik und Poliklinik, Universität Rostock.
authors.forename: H
authors.initials: H
authors.lastname: Seiter
authors.forename: K P
authors.initials: KP
authors.lastname: Schmitz
authors.forename: D
authors.initials: D
authors.lastname: Behrend
mesh_terms: D001672:Biocompatible Materials; D002408:Catheters, Indwelling; D006801:Humans; D008422:Materials Testing; D019736:Prostheses and Implants; D014546:Urinary Catheterization / Q000295:instrumentation; D014570:Urologic Diseases / Q000601:surgery*
chemical_list: D001672:Biocompatible Materials