title: [Life-threatening echovirus 11 infection during first month of life].
abstract: Infection with Echovirus 11 is mostly asymptomatic, but it may cause a wide variety of clinical diseases, from gastroenteritis to serious diseases such as meningitis and myocarditis. In small infants, especially during the first days of life, echovirus infection may appear as a sepsis-like illness, and cause disseminated intravascular coagulopathy and shock. We present 2 infants with severe Echovirus 11 infections. A 3.5-month-old died within 24 hours of shock and probably myocarditis. The other, 6-days old, presented with meningitis, hepatitis and disseminated intravascular coagulopathy. It recovered after treatment with intravenous immunoglobulin. Echovirus 11 may cause life-threatening infections in small infants. Pediatricians should be alert to the special characteristics of this disease.
authors.affiliation: Neonatal Dept., Laniado Hospital, Kiriat Zans, Natanya.
authors.forename: U
authors.initials: U
authors.lastname: Rubinstein
authors.forename: M
authors.initials: M
authors.lastname: Weisbrod
authors.forename: B
authors.initials: B
authors.lastname: Garty
mesh_terms: D004211:Disseminated Intravascular Coagulation / Q000209:etiology / Q000628:therapy; D004457:Echovirus Infections / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007231:Infant, Newborn; D008297:Male; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous