title: Efficacy of inhalation form of furosemide to prevent postsurgical relapses of rhinosinusal polyposis.
abstract: The aim of the work is to demonstrate the efficacy of furosemide to prevent relapses of rhinosinusal polyps after surgical treatment. Two groups of people with rhinosinusal polyposis were enrolled: the study group consisted of 64 patients and the control group of 40 subjects. After surgical treatment, the study group started the therapy with topical furosemide; the control group had no treatment administered after the operation. Six years after the operation only 4 cases of relapse were noticed in the study group (10%), while there were 12 relapses, 4 slight (6.4%) and 8 severe (20%), in the control group. In conclusion, furosemide could represent a valid therapeutic aid in the prevention of nasosinusal polyps.
authors.affiliation: ENT Department, University of Siena, Medical School, Siena, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Passàli
authors.forename: C
authors.initials: C
authors.lastname: Mezzedimi
authors.forename: G C
authors.initials: GC
authors.lastname: Passàli
authors.forename: L
authors.initials: L
authors.lastname: Bellussi
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D005260:Female; D005665:Furosemide / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000517:prevention & control* / Q000601:surgery; D011182:Postoperative Care; D055502:Secondary Prevention; D016896:Treatment Outcome
chemical_list: D005665:Furosemide