[Bone density and its quality].
The paper presents the newest knowledge on bones quality, which becomes the main criterion for evaluation of fracture risks and osteoporosis treatment effects. It is necessary to develop new methods of measurement and quantification of bones quality, with regard to the properties of all bone structures, not solely the bone mineral density (BMD) as it was until now. From the most recent studies follows: 1. bone stiffness depends not only on BMD but also on the bone quality, 2. antiosteoporotic treatment can reduce the fracture incidence without significant rise of BMD, 3. BMD is not always an reliant marker of all treatment procedures efficiency in osteoporosis, 4. it is necessary to develop new diagnostic methods for bone quality quantification with the possibility of exact fracture risk determination, 5. in future the influence of antiosteoporotic drugs on bone quality, i.e. on all structures, not only BMD, will be studied. (Ref. 8.)
Wendlova
J
J
Osteologic Office, University Hospital with Outpatient Clinic of L. Derer, Bratislava, Slovakia. wendlj@slofa.sk
D015519:Bone Density; D050723:Fractures, Bone / Q000209:etiology; D006801:Humans; D010024:Osteoporosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D012307:Risk Factors