Metastatic carcinoma in a transposed ovary after radical hysterectomy for a stage 1B cervical adenosquamous cell carcinoma. Case report.
A 41-year-old multigravida woman presented with a cervical stage 1b adenosquamous cell carcinoma with metastasis in a transposed ovary. Twenty-four months following a radical hysterectomy for cervical cancer a CT scan revealed a mass measuring 7x6x4 cm in size lateral to the ascending colon. The pathological diagnosis showed the mass to be metastatic adenocarcinoma in the transposed ovary which was considered to be adenocarcinoma from the previous cervical adenosquamous cell carcinoma. Thereafter, she was administered a combination of mitomycin C, etoposide and cisplatin (MEP) three times. One year following the completion of the chemotherapy she is still alive without any definitive recurrence. It is important to clarify whether or not ovarian transposition is safe and effective in helping surgeons determine whether or not to preserve the ovarian function for a young patient likely to undergo postoperative irradiation for early invasive cervical cancer. In the present report, we also review the current literature on this subject and discuss our findings.
Shigematsu
T
T
Department of Obstetrics and Gynecology, Miyazaki Prefectural Hospital, Japan.
Ohishi
Y
Y
Fujita
T
T
Higashihara
J
J
Irie
T
T
Hayashi
T
T
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018196:Carcinoma, Adenosquamous / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007044:Hysterectomy; D016685:Mitomycin / Q000008:administration & dosage; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D010052:Ovariectomy; D010053:Ovary / Q000601:surgery*; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery
D016685:Mitomycin; D005047:Etoposide; D002945:Cisplatin