title: Involuntary weight loss and the nonhealing wound.
abstract: Wounds elicit a hypermetabolic, net catabolic state that can precipitate profound involuntary weight loss, particularly in the lean tissue compartment. To promote anabolic conditions more conducive to wound healing, an integrated treatment approach is warranted. Effective management includes optimal wound care, treatment or prevention of infection, nutritional intervention (e.g., protein supplementation), moderate exercise, and adjunctive anabolic treatment in patients whose involuntary weight loss has reached at least 10% of usual body weight.
authors.affiliation: Health South Braintree Rehabilitation Center, MA, USA.
authors.forename: L
authors.initials: L
authors.lastname: DeSanti
mesh_terms: D001823:Body Composition; D015984:Causality; D006801:Humans; D015596:Nutrition Assessment; D018529:Nutritional Support / Q000379:methods; D011502:Protein-Energy Malnutrition / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D015431:Weight Loss; D014945:Wound Healing