[Systemic mastocytosis].
Mastocytosis has a highly variable clinical expression, and systemic mastocytosis is occasionally associated with a myeloproliferative or a myelodysplastic disorder. These patients often present without skin involvement and have a very poor prognosis. We report a 72-year-old man with this condition who had spells of flushing and dyspnea, myelofibrosis, and high serum and urine histamine levels.
Sade
K
K
Dept. of Pulmonary Diseases, Tel Aviv-Sourasky Medical Center.
Dotan
I
I
Levo
Y
Y
D000368:Aged; D004359:Drug Therapy, Combination; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D006919:Hydroxyzine / Q000627:therapeutic use; D008297:Male; D008415:Mastocytosis / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D011899:Ranitidine / Q000627:therapeutic use
D006634:Histamine H1 Antagonists; D006635:Histamine H2 Antagonists; D006919:Hydroxyzine; D011899:Ranitidine