Corticosteroid-responsive diabetes mellitus associated with autoimmune pancreatitis.
Autoimmune pancreatitis, which can be treated with corticosteroid therapy, has the potential to induce diabetes. In a cohort study of 2220 patients with suspected chronic pancreatitis, we found that all four patients with autoimmune chronic pancreatitis also had diabetes. Treatment with prednisolone subsequently improved insulin secretion and glycaemic control in these patients.
Tanaka
S
S
Kobayashi
T
T
Nakanishi
K
K
Okubo
M
M
Murase
T
T
Hashimoto
M
M
Takeuchi
K
K
D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001327:Autoimmune Diseases / Q000150:complications* / Q000188:drug therapy; D001786:Blood Glucose / Q000032:analysis; D002908:Chronic Disease; D015331:Cohort Studies; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000188:drug therapy; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D006942:Hypergammaglobulinemia / Q000209:etiology / Q000628:therapy; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D008297:Male; D010195:Pancreatitis / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D011239:Prednisolone / Q000627:therapeutic use*
D000893:Anti-Inflammatory Agents; D001786:Blood Glucose; D005938:Glucocorticoids; D007004:Hypoglycemic Agents; D007328:Insulin; D011239:Prednisolone