Synthesis of heterocyclic quinones containing bridgehead nitrogen atom from 2-aminonaphtho[2,3-d]thiazole-4,9-dione.
Imidazonaphthothiazole derivatives 3-6 were prepared by treatment of 2-aminonaphtho[2,3-d]-thiazole-4,9-dione(1) with phenacyl bromide, chloroacetic acid, diethyl oxalate and 2,3-dichloroquinoxaline respectively. The reaction of 1 with ethyl acrylate, ethyl acetoacetate and diethyl malonate gave the corresponding naphthothiazolopyrimidine derivatives 8-11.
Fandy
R F
RF
Chemistry Department, Faculty of Science, South Valley University, Qena, Egypt. rffandy1@yahoo.com
D000935:Antifungal Agents / Q000138:chemical synthesis*; D011809:Quinones / Q000138:chemical synthesis*; D013844:Thiazoles
D000935:Antifungal Agents; D011809:Quinones; D013844:Thiazoles