Pentasomy 8 in pediatric myelodysplastic syndrome.
Myelodysplastic syndrome developed in a 2-year-old child with the karyotype revealing the presence of pentasomy 8. The significance of the coexistence of pentasomy 8, tetrasomy 8, and trisomy 8 detected by fluorescence in situ hybridization in his marrow is discussed.
Wong
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WY
Division of Hematology-Oncology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Wu
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SQ
D000782:Aneuploidy; D002675:Child, Preschool; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008297:Male; D009190:Myelodysplastic Syndromes / Q000235:genetics*