Haemangioblastoma of a cervical sensory nerve root in Von Hippel-Lindau syndrome.
Spinal haemangioblastomas are rare, accounting for only about 7% of all central nervous system cases. The case of a 40-year-old woman with a haemangioblastoma arising solely from a cervical sensory nerve root is presented. At operation via a cervical laminectomy, it was possible to resect the tumour en masse with the sensory ramus, by extending the laminectomy through the exit foramen for C6. Haemangioblastomas are commonly intramedullary, and have only been reported in this location on one previous occasion. The patient has Von Hippel-Lindau syndrome and a history of multiple solid tumours. The possible role of the Von Hippel-Lindau tumour suppressor gene in the pathogenesis of these neoplasms is discussed.
McEvoy
A W
AW
The University Deparment of Neurosurgery, University College London, The Institute of Neurology, The National Hospital for Neurology and Neurosurgery, UK. a.mcevoy@ion.ucl.ac.uk
Benjamin
E
E
Powell
M P
MP
D000328:Adult; D005260:Female; D018325:Hemangioblastoma / Q000209:etiology* / Q000601:surgery; D006801:Humans; D009333:Neck; D010524:Peripheral Nervous System Neoplasms / Q000209:etiology* / Q000601:surgery; D013126:Spinal Nerve Roots; D006623:von Hippel-Lindau Disease / Q000150:complications*