A case report of refractory obsessive-compulsive disorder improved by risperidone augmentation of clomipramine treatment.
A male patient aged 43 years, suffering from symptoms of obsessive-compulsive disorder (OCD), such as washing hands and feet frequently and checking documents compulsively, had received intensive pharmacotherapeutic and behavior therapy. Although the administration of anxiolytic drugs and/or clomipramine did not show curative effects, a combination of clomipramine and risperidone showed much greater effect in improving these symptoms.
Kawahara
T
T
Department of Psychiatry, Miyazaki Medical College, Kiyotake, Japan. kawahara@post1.miyazaki-med.ac.jp
Ueda
Y
Y
Mitsuyama
Y
Y
D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002997:Clomipramine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006760:Hospitalization; D006801:Humans; D007902:Length of Stay; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy* / Q000534:rehabilitation; D018967:Risperidone / Q000627:therapeutic use*
D000929:Antidepressive Agents, Tricyclic; D014150:Antipsychotic Agents; D018967:Risperidone; D002997:Clomipramine