Management of ventricular tachycardia in patients with clinically normal hearts.
The majority of patients who present with ventricular tachycardia have underlying structural heart disease. However, there has been increasing appreciation of the existence of multiple forms of idiopathic ventricular tachycardia with distinct features and unique mechanisms. The most common form of idiopathic ventricular tachycardia originates from the right ventricular outflow tract, is characterized by sensitivity to adenosine, and appears to be due to cyclic AMP-mediated triggered activity. Other forms of idiopathic ventricular tachycardia include intrafascicular left ventricular tachycardia, due to reentry, which is sensitive to verapamil, and automatic, propranolol-sensitive ventricular tachycardia.
Iwai
S
S
Department of Medicine, Division of Cardiology, The New York Hospital-Cornell University Medical Center, 525 East 68th Street, Starr 409, New York, NY 10021, USA.
Lerman
B B
BB
D000241:Adenosine / Q000008:administration & dosage; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D017115:Catheter Ablation / Q000379:methods*; D004562:Electrocardiography; D005260:Female; D006334:Heart Function Tests; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D011379:Prognosis; D011433:Propranolol / Q000008:administration & dosage; D015996:Survival Rate; D017180:Tachycardia, Ventricular / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D016896:Treatment Outcome; D014700:Verapamil / Q000008:administration & dosage
D000889:Anti-Arrhythmia Agents; D011433:Propranolol; D014700:Verapamil; D000241:Adenosine