Possible mechanisms of late-life-onset allergic diseases and asthma in the senior citizen.
The clinical spectrum of allergic diseases and asthma changes over the life span of the individual and is influenced by a wide variety of anatomic, physiologic, and immunologic factors. Nowhere do these changes play a more important role than in the elderly patient with allergic disease or asthma where the culmination of these events contribute to disease expression, which at times can result in irreversible endstage disease. It is estimated that between 2010 and 2030 the elderly population will increase by 75% and will represent a significant proportion of consumers of total health care resources. This presentation will examine possible mechanism(s) that contribute to the development of late-onset allergic diseases and asthma in the elderly as a possible basis for identification of antecedents of endstage disease and interventive strategies for the prevention of the irreversible consequences in this population.
Bellanti
J A
JA
Department of Pediatrics, Georgetown University Medical Center, Washington, DC 20007, USA.
Azem
M
M
MacDowell-Carneiro
A L
AL
Tutuncuoglu
S O
SO
Wallerstedt
D B
DB
D017668:Age of Onset; D000368:Aged; D000375:Aging / Q000276:immunology; D001249:Asthma / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D003937:Diagnosis, Differential; D006801:Humans; D012221:Rhinitis, Allergic, Perennial / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control