Cirrhosis mortality among former American prisoners of war of World War II and the Korean conflict: results of a 50-year follow-up.
In our earlier, 30-year follow-up of American prisoners of war (POWs) of World War II and the Korean conflict, we found evidence of increased cirrhosis mortality. Using federal records, we have now extended our follow-up to 50 years (42 years for Korean conflict veterans) and have used proportional hazards analysis to compare the mortality experience of POWs with that of controls. Compared with their controls, World War II POWs had a 32% higher risk of cirrhosis mortality (statistically significant), and mortality risk was higher in the first 30 years of follow-up and also among those aged 51 years and older. Korean POWs had roughly the same risk of cirrhosis mortality as their controls. Neither self-reported data on alcohol consumption nor supplemental morbidity data satisfactorily explained the differences in risk between POWs and controls, although there was evidence that POWs tended to have higher rates of hepatitis, helminthiasis, and nutritional deprivation.
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Medical Follow-Up Agency, Institute of Medicine, National Academy of Sciences, Washington, DC 20418, USA.
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D016022:Case-Control Studies; D002423:Cause of Death; D002908:Chronic Disease; D003644:Death Certificates; D005060:Europe; D005500:Follow-Up Studies; D006801:Humans; D007723:Korea; D008103:Liver Cirrhosis / Q000209:etiology / Q000401:mortality*; D008113:Liver Neoplasms / Q000453:epidemiology; D009017:Morbidity; D010139:Pacific Islands; D015995:Prevalence; D011329:Prisoners / Q000706:statistics & numerical data*; D016016:Proportional Hazards Models; D012307:Risk Factors; D014481:United States / Q000453:epidemiology; D014728:Veterans / Q000706:statistics & numerical data*; D014857:Warfare