title: [Prevalence of anti-hantavirus antibodies in health care personnel in direct contact with patients with hantavirus pulmonary syndrome in Temuco, Chile 1997 to 1999].
abstract: BACKGROUND
  An outbreak of Hantavirus Cardiopulmonary Syndrome (HVCS) caused by the Andes virus, affected Chile since 1995. Antibodies to Hantavirus in health care workers who had cared patients with HVCS in Coybaique, Argentinean reports and familial clustering of bantaviral illness, raised the possibility of person to person transmission. Familial clustering could occur secondary to a similar exposure to a common infected environment of more than one member of the family. Moreover, the prevalence of antibodies in health care workers in Coyhaique does not differ from the prevalence in general population in that region.
  
  
  OBJECTIVE
  To study the prevalence of antibodies to Hantavirus in health care workers exposed to body fluids of 20 patients.
  
  
  METHODS
  Among health care workers exposed to patients with HVCS, we registered information about the exposure to patients and to the environment outside the hospital in which they could have been infected. IgG antibodies against Hantavirus were measured by ELISA using two dilutions.
  
  
  RESULTS
  Sixty seven workers were studied. Of these, 73% were exposed to respiratory secretions and blood, 21% to blood and 6% to respiratory secretions. Only 6% protected themselves properly, 49% used facial masks and gloves, 25% only facial masks, 7% only gloves and 12% used no protection measures. In none of these workers, Hantavirus antibodies were detected.
  
  
  CONCLUSIONS
  These results are supporting evidence against person to person transmission of the Andes virus.
authors.affiliation: Universidad de la Frontera, Temuco. medint@ufro.cl
authors.forename: C
authors.initials: C
authors.lastname: Castillo
authors.forename: J
authors.initials: J
authors.lastname: Mardones
authors.forename: E
authors.initials: E
authors.lastname: Villagra
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D002677:Chile / Q000453:epidemiology; D004797:Enzyme-Linked Immunosorbent Assay; D006476:Orthohantavirus / Q000276:immunology*; D018804:Hantavirus Pulmonary Syndrome / Q000453:epidemiology / Q000276:immunology / Q000635:transmission*; D006282:Health Personnel; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional / Q000706:statistics & numerical data*; D008875:Middle Aged; D016273:Occupational Exposure / Q000706:statistics & numerical data; D012307:Risk Factors; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral