Metabolic labeling of glycoproteins with chemical tags through unnatural sialic acid biosynthesis.
Jacobs
C L
CL
Department of Chemistry, University of California at Berkeley 94720, USA.
Yarema
K J
KJ
Mahal
L K
LK
Nauman
D A
DA
Charters
N W
NW
Bertozzi
C R
CR
D000818:Animals; D001671:Biochemistry / Q000379:methods*; D002460:Cell Line; D002462:Cell Membrane / Q000378:metabolism; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D005434:Flow Cytometry; D006023:Glycoproteins / Q000737:chemistry* / Q000378:metabolism*; D006367:HeLa Cells; D006595:Hexosamines / Q000037:antagonists & inhibitors / Q000096:biosynthesis / Q000494:pharmacology; D006801:Humans; D019169:Jurkat Cells; D007659:Ketones / Q000378:metabolism; D008856:Microscopy, Fluorescence; D008954:Models, Biological; D019158:N-Acetylneuraminic Acid / Q000096:biosynthesis / Q000737:chemistry* / Q000378:metabolism*; D013379:Substrate Specificity; D013997:Time Factors
D006023:Glycoproteins; D006595:Hexosamines; D007659:Ketones; C105871:N-levulinoyl mannosamine; D019158:N-Acetylneuraminic Acid; C002022:N-acetylmannosamine