title: Surgical management of lung gangrene.
abstract: OBJECTIVE
  To review the outcomes of five cases of pulmonary resection for lung gangrene.
  
  
  METHODS
  A retrospective chart review.
  
  
  METHODS
  A tertiary referral centre.
  
  
  METHODS
  Five patients who underwent pulmonary resection for lung gangrene between April and December 1999.
  
  
  RESULTS
  Pathological confirmation of lung gangrene was obtained in all cases. Three patients were ventilator dependent. All five patients had ongoing sepsis despite antibiotic therapy. Additional indications for resection included bronchopleural fistula (two patients), empyema (three patients) and hemoptysis (one patient). In two cases, there was evidence of bilateral, diffuse necrotizing pneumonia, while in three cases the process was localized to one side. Computed tomography revealed cavitation in four cases and the absence of blood supply to the affected lung in one case. Surgical resection included wedge resection (one patient), lobectomy (two patients), bilobectomy (one patient) and pneumonectomy (one patient). In all cases, the bronchial stump was reinforced with an intercostal flap. Postoperative empyema occurred in two cases, one treated by thoracoscopic decortication, the other by percutaneous drainage. There were no instances of stump leak and no deaths. One patient remains ventilator dependent.
  
  
  CONCLUSIONS
  Resection for lung gangrene is possible even in the setting of diffuse parenchymal changes and ventilator dependency. A computed tomography scan of the chest is important to make the diagnosis of lung gangrene and to plan operative management. Reinforcement of the bronchial stump is critical.
authors.affiliation: University of Washington, Seattle, WA 98195, USA.
authors.forename: B
authors.initials: B
authors.lastname: Krishnadasan
authors.forename: V L
authors.initials: VL
authors.lastname: Sherbin
authors.forename: E
authors.initials: E
authors.lastname: Vallières
authors.forename: R
authors.initials: R
authors.lastname: Karmy-Jones
mesh_terms: D000328:Adult; D005260:Female; D005734:Gangrene / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery; D006801:Humans; D008168:Lung / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D011013:Pneumonectomy; D011014:Pneumonia / Q000150:complications; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed