Influence of photodynamic therapy on immunological aspects of disease - an update.
Photodynamic therapy (PDT) utilises light-absorbing compounds combined with directed photo-irradiation to produce clinical effects. This review updates advances in the understanding of the biochemical pathways triggered by PDT within cells, its influence upon different immune parameters and progress in the use of PDT against human immune-mediated disease. Several works have further defined the notable capacity of PDT to foster anticancer immunity.
Hunt
D W
DW
QLT PhotoTherapeutics, Inc., 887 Great Northern Way, Vancouver, British Columbia V5T 4T5, Canada. dhunt@qltinc.com
Chan
A H
AH
D000818:Animals; D006801:Humans; D007154:Immune System Diseases / Q000188:drug therapy*; D009369:Neoplasms / Q000188:drug therapy* / Q000628:therapy*; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*
D017319:Photosensitizing Agents