title: One-step hysteroscopic removal of sinking submucous myoma in two infertile patients.
abstract: OBJECTIVE
  To report one-step resectoscopic removal of submucous myomas that were pushed back into the muscular layer by increased intrauterine pressure during hysteroscopic procedures.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Kawasaki Municipal Hospital, Kawasaki, Japan.
  
  
  METHODS
  Two infertile women presenting with menorrhagia in whom submucous myoma with a broad base was diagnosed.
  
  
  METHODS
  One patient was pretreated with GnRH agonist for 4 months; the other patient did not receive this treatment. Resectoscopic myomectomies were performed under close sonographic monitoring.
  
  
  METHODS
  Clinical symptoms and conception status.
  
  
  RESULTS
  Tumor sinking occurred during the hysteroscopic procedures, but complete resectoscopic removal of the submucous myomas was achieved under sonographic and hysteroscopic visualization. One patient experienced hyponatremia but recovered after conservative treatment. Both patients conceived after myoma removal.
  
  
  CONCLUSIONS
  Sinking myomas, which may cause infertility, can be removed with a one-step hysteroscopic procedure. Sinking of submucous myomas during hysteroscopy might be caused by pretreatment with GnRH agonist and by increased intrauterine pressure during hysteroscopy. We recommend that intrauterine pressure be <45 mmHg, equivalent to hanging a bag of fluid under gravity control 70 cm above the patient's uterus, at the beginning of operations for sinking myomas.
authors.affiliation: Department of Obstetrics and Gynecology, Kawasaki Municipal Hospital, Kawasaki, Japan. Lin@kmh.gr.jp
authors.forename: B
authors.initials: B
authors.lastname: Lin
authors.forename: Y
authors.initials: Y
authors.lastname: Akiba
authors.forename: Y
authors.initials: Y
authors.lastname: Iwata
mesh_terms: D000328:Adult; D004724:Endoscopy; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists; D006801:Humans; D007010:Hyponatremia / Q000209:etiology; D015907:Hysteroscopy; D007247:Infertility, Female / Q000209:etiology*; D008595:Menorrhagia / Q000209:etiology; D009214:Myoma / Q000000981:diagnostic imaging / Q000601:surgery*; D011183:Postoperative Complications; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*
chemical_list: D007987:Gonadotropin-Releasing Hormone