title: Power Doppler ultrasound of gallbladder wall vascularization in inflammation: clinical implications.
abstract: We investigated the role of Power Doppler US in the diagnosis and follow-up of cholecystitis. We reviewed the examinations of 21 surgical patients aged 27-48 years with US findings of cholecystitis. We performed B-mode and then Power Doppler US. Wall thickness and US structure, the presence/absence of stones, and US Murphy's sign were assessed at B-mode US, whereas only the presence/absence of wall vascularization was studied with Power Doppler. B-mode and Power Doppler changes post treatment were also investigated. Ultrasound showed wall thickening in all patients. In addition, positive Murphy's sign and/or gallbladder stones were seen in 6 patients each at B-mode US and wall vascularization in 7 patients with Power Doppler. Acute cholecystitis was diagnosed in these patients. The other 14 patients presenting wall thickening but no vascularization and negative US Murphy's sign were diagnosed as having chronic cholecystitis; 10 of them had gallbladder stones. Two of seven acute cholecystitis patients were operated on in the acute stage for the onset of complications and histologic findings confirmed the US diagnosis. As for the remaining patients, histology diagnosed chronic cholecystitis in 17, whereas wall thickening was not inflammatory in 2 cases. All the cases with early wall vascularization were eventually diagnosed as cholecystitis. Power Doppler US permits confirmation of the diagnosis of acute cholecystitis and distinguishing of chronic disease, which helps in planning of surgery.
authors.affiliation: Istituto di Radiologia dell'Università, IRCCS Policlinico S. Matteo, Pavia, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Draghi
authors.forename: G
authors.initials: G
authors.lastname: Ferrozzi
authors.forename: F
authors.initials: F
authors.lastname: Calliada
authors.forename: M
authors.initials: M
authors.lastname: Solcia
authors.forename: L
authors.initials: L
authors.lastname: Madonia
authors.forename: R
authors.initials: R
authors.lastname: Campani
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001783:Blood Flow Velocity; D002763:Cholecystectomy; D002764:Cholecystitis / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D005704:Gallbladder / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D018608:Ultrasonography, Doppler