Thromboelastography identifies sex-related differences in coagulation.
Thromboelastography is an in vitro, point-of-care monitor of whole blood coagulation. Thromboelastography studies have demonstrated a hypercoagulable state during pregnancy. Perhaps the hypercoagulability is attributable to female sex hormones. The aim of the study was to determine if sex, in addition to pregnancy, affected thromboelastography variables by studying male and female (pregnant and nonpregnant) volunteers. Thromboelastography showed significant (P:<0.01) differences in sex, with a significant (P: < 0. 0001) trend of increasing whole blood coagulability from men through nonpregnant to pregnant women. The thromboelastograph, used as a diagnostic tool, shows that women have more whole blood coagulability than men.


CONCLUSIONS
The thromboelastograph, used as a diagnostic tool, shows that women have more whole blood coagulability than men.
Gorton
H J
HJ
Department of Anesthesia, St. James's University Hospital, Leeds, United Kingdom. heather@westcroft.u-net.com
Warren
E R
ER
Simpson
N A
NA
Lyons
G R
GR
Columb
M O
MO
D000328:Adult; D001777:Blood Coagulation; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D012727:Sex Characteristics; D013916:Thrombelastography