Actin cytoskeleton: putting a CAP on actin polymerization.
Two recent studies have identified a Drosophila homolog of cyclase-associated protein (CAP) as a developmentally important negative regulator of actin polymerization that may also directly mediate signal transduction.
Stevenson
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VA
Program in Molecular Medicine and the Department of Molecular Genetics and Microbiology, University of Massachusetts Medical Center, 373 Plantation Street, Worcester, Massachusetts 01605, USA.
Theurkauf
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WE
D000199:Actins / Q000378:metabolism*; D001704:Biopolymers; D018797:Cell Cycle Proteins / Q000378:metabolism* / Q000502:physiology; D003598:Cytoskeletal Proteins; D003599:Cytoskeleton / Q000378:metabolism*; D029721:Drosophila Proteins; D008840:Microfilament Proteins; D015398:Signal Transduction
D000199:Actins; D001704:Biopolymers; C410502:Capt protein, Drosophila; D018797:Cell Cycle Proteins; D003598:Cytoskeletal Proteins; D029721:Drosophila Proteins; D008840:Microfilament Proteins