title: Cholic acid is accumulated spontaneously, driven by membrane deltapH, in many lactobacilli.
abstract: Many lactobacilli from various origins were found to apparently lack cholic acid extrusion activity. Cholic acid was accumulated spontaneously, driven by the transmembrane proton gradient. Accumulation is a newly identified kind of interaction between intestinal microbes and unconjugated bile acids and is different from extrusion and modification, which have been described previously.
authors.affiliation: Laboratory of Applied Microbiology, Research Group of Molecular Bioscience, Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University, Sapporo 060-8589, Japan.
authors.forename: P
authors.initials: P
authors.lastname: Kurdi
authors.forename: H W
authors.initials: HW
authors.lastname: van Veen
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.forename: I
authors.initials: I
authors.lastname: Mierau
authors.forename: W N
authors.initials: WN
authors.lastname: Konings
authors.forename: G W
authors.initials: GW
authors.lastname: Tannock
authors.forename: F
authors.initials: F
authors.lastname: Tomita
authors.forename: A
authors.initials: A
authors.lastname: Yokota
mesh_terms: D001692:Biological Transport; D019826:Cholic Acid / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D007778:Lactobacillus / Q000378:metabolism*
chemical_list: D019826:Cholic Acid