title: Pre-natal sensitization in humans.
abstract: Allergy has a very strong hereditary component but even in identical twins, concordance for the development of allergic disease can be as low as 50%. This suggests that there is a very strong environmental influence on manifestations of sensitization. To what extent environment might have an influence on the ontogeny of sensitization antenatally has hitherto not been a focus of much research. However, circumstantial evidence suggests that this may be important.
authors.affiliation: Child Health, University of Southampton/Southampton General Hospital, UK. jow@soton.ac.uk
authors.forename: J O
authors.initials: JO
authors.lastname: Warner
authors.forename: C A
authors.initials: CA
authors.lastname: Jones
authors.forename: S A
authors.initials: SA
authors.lastname: Kilburn
authors.forename: G H
authors.initials: GH
authors.lastname: Vance
authors.forename: J A
authors.initials: JA
authors.lastname: Warner
mesh_terms: D000485:Allergens / Q000276:immunology*; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000235:genetics / Q000276:immunology*; D007109:Immunity; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects
chemical_list: D000485:Allergens