title: [Antagonist-induced opiate detoxification. Report on clinical experience as well as on short and intermediate range course].
abstract: In a special inpatient unit for detoxification treatment of illicit drugs, antagonist-induced opiate detoxification was studied in five nonselected inpatients with polytoxicomanic abuse. The purpose was to evaluate the feasibility of this detoxification method and its impact on further reaction to treatment. During rapid detoxification under general anesthesia in an intensive care unit, no complications occurred. Withdrawal symptoms were observed in all patients over several days. During the inpatient period, no patient could be motivated to take part in a longer rehabilitation therapy. Most patients were discharged prematurely on their own demand and none made use of the rehabilitation program offered to them. All patients relapsed after relatively short times and three out of five presented for a new detoxification treatment.
authors.affiliation: Psychiatrische Klinik, Heinrich-Heine-Universität Düsseldorf. burtsche@uni-duesseldorf.de
authors.forename: C
authors.initials: C
authors.lastname: Boehle
authors.forename: D
authors.initials: D
authors.lastname: Kindgen-Milles
authors.forename: W
authors.initials: W
authors.lastname: Burtscheidt
authors.forename: J
authors.initials: J
authors.lastname: Tarnow
authors.forename: W
authors.initials: W
authors.lastname: Gaebel
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D004359:Drug Therapy, Combination; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D005858:Germany; D006801:Humans; D007297:Inpatients / Q000523:psychology; D008297:Male; D009270:Naloxone / Q000008:administration & dosage* / Q000627:therapeutic use; D009292:Narcotic Antagonists / Q000008:administration & dosage* / Q000627:therapeutic use; D009293:Opioid-Related Disorders / Q000628:therapy*; D010352:Patient Dropouts; D012008:Recurrence; D012720:Severity of Illness Index; D013375:Substance Withdrawal Syndrome / Q000517:prevention & control*; D019966:Substance-Related Disorders / Q000628:therapy
chemical_list: D009292:Narcotic Antagonists; D009270:Naloxone