Necrotizing granulomata of the aortic valve in Wegener's disease.
Wegener's disease is an inflammatory disease of unknown etiology, characterized by a granulomatous-necrotizing general vasculitis. Cardiac involvement in the form of aortic pathology is not frequent. We report a case of Wegener's granulomatosis which required prosthetic aortic valve replacement for aortic valve insufficiency. Microscopic examination of the valve demonstrated histopathology typical of Wegener's disease.
Bruno
P
P
Thoracic and Cardiovascular Surgery Department, University Hospital Caen, France.
Le Hello
C
C
Massetti
M
M
Babatasi
G
G
Saloux
E
E
Galateau
F
F
Khayat
A
A
D001021:Aortic Valve / Q000473:pathology*; D001022:Aortic Valve Insufficiency / Q000209:etiology / Q000601:surgery; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications / Q000473:pathology*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008875:Middle Aged; D009336:Necrosis