title: The osmotic swelling characteristics of cardiac valve prostheses.
abstract: Several types of mechanical cardiac prostheses have been constructed with Delrin occluders, a material that is subject to osmotic swelling. The leaftets are designed to expand to specific tolerances when immersed in blood. The synthetic blood analogs commonly used in vitro contain hydrophilic compounds that can alter the osmotic expansion of the Delrin occluders. A static leak test chamber was employed to illustrate the effects of various test fluids on the sustained regurgitation phase of Delrin valves.
authors.affiliation: Bioengineering Department, Pennsylvania State University, University Park 16802, USA.
authors.forename: C
authors.initials: C
authors.lastname: Bachmann
authors.forename: M
authors.initials: M
authors.lastname: Wilson
authors.forename: V
authors.initials: V
authors.lastname: Kini
authors.forename: S
authors.initials: S
authors.lastname: Deutsch
authors.forename: A A
authors.initials: AA
authors.lastname: Fontaine
authors.forename: J M
authors.initials: JM
authors.lastname: Tarbell
mesh_terms: D019544:Equipment Failure Analysis; D005990:Glycerol; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008422:Materials Testing / Q000379:methods*; D009995:Osmosis; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012117:Resins, Synthetic / Q000009:adverse effects*; D012965:Sodium Chloride; D012974:Sodium Iodide; D013997:Time Factors
chemical_list: D012117:Resins, Synthetic; D012965:Sodium Chloride; C010102:delrin; D012974:Sodium Iodide; D005990:Glycerol