title: New functions from old scaffolds: how nature reengineers enzymes for new functions.
authors.affiliation: Department of Biopharmaceutical Sciences, University of California, San Francisco 94143, USA.
authors.forename: P C
authors.initials: PC
authors.lastname: Babbitt
authors.forename: J A
authors.initials: JA
authors.lastname: Gerlt
mesh_terms: D000595:Amino Acid Sequence; D004798:Enzymes / Q000737:chemistry*; D008956:Models, Chemical; D008969:Molecular Sequence Data; D015202:Protein Engineering; D017386:Sequence Homology, Amino Acid
chemical_list: D004798:Enzymes