title: BRCA1: exploring the links to transcription.
abstract: Progress on determining the function of the breast and ovarian cancer susceptibility gene BRCA1 suggests it might be involved in two fundamental cellular processes: DNA repair and transcriptional regulation. Recent developments indicate that BRCA1 is a multifunctional protein, and disruption of its transcriptional activity could be crucial for tumor development.
authors.affiliation: Dept of Cell Biology, Weill Medical College of Cornell University, New York, NY 10021, USA.
authors.forename: A N
authors.initials: AN
authors.lastname: Monteiro
mesh_terms: D019313:BRCA1 Protein / Q000235:genetics* / Q000378:metabolism*; D004260:DNA Repair; D006801:Humans; D012319:RNA Polymerase II / Q000378:metabolism*; D014158:Transcription, Genetic; D015533:Transcriptional Activation
chemical_list: D019313:BRCA1 Protein; D012319:RNA Polymerase II