title: Potential role of famciclovir for prevention of herpetic whitlow in the health care setting.
abstract: Oral famciclovir was initiated in a health care worker immediately after an accidental percutaneous injury involving a needle freshly removed from a patient's herpes labialis vesicles. In follow-up, the health care worker remained seronegative for herpes simplex I and II antibodies (IgG and IgM) and did not develop herpetic whitlow, supporting the potential role of famciclovir in the prevention of herpetic whitlow in a health care setting.
authors.affiliation: Division of Infectious Diseases, St. John's Mercy Medical Center, St. Louis, MO 63141, USA. Persprince@aol.com.
authors.forename: F A
authors.initials: FA
authors.lastname: Manian
mesh_terms: D015075:2-Aminopurine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D000284:Administration, Oral; D000914:Antibodies, Viral / Q000097:blood; D000998:Antiviral Agents / Q000008:administration & dosage*; D000077595:Famciclovir; D005385:Fingers; D006282:Health Personnel; D006561:Herpes Simplex / Q000276:immunology / Q000517:prevention & control*; D018259:Herpesvirus 1, Human / Q000276:immunology; D018258:Herpesvirus 2, Human / Q000276:immunology; D006801:Humans; D008297:Male; D016602:Needlestick Injuries / Q000188:drug therapy; D009784:Occupational Diseases / Q000517:prevention & control
chemical_list: D000914:Antibodies, Viral; D000998:Antiviral Agents; D015075:2-Aminopurine; D000077595:Famciclovir