title: [Carotid endarterectomy and carotid stenting. A pilot study of a prospective, randomized and controlled comparison].
abstract: BACKGROUND
  A prospective, randomized and controlled trial is conducted to compare carotid endarterectomy and carotid stenting in high grade symptomatic carotid artery stenoses.
  
  
  METHODS
  According to the study design symptomatic patients with a angiographically high-grade (> or = 70%) internal carotid artery stenosis are included. Pre- and postinterventional diagnostics during the hospitalization period includes neurological assessment, duplex sonography of the cervical and cerebral arteries and magnetic resonance imaging of the brain. Follow-up examinations are scheduled after 1, 6 and 12 months and consist of a neurological assessment and duplex sonography. After 12 months selective angiography and magnetic resonance imaging of the brain will be performed additionally. During a period of 9 months up to now 23/137 patients treated for a carotid artery stenosis were included in the study, 11 patients underwent surgery and 12 patients carotid stenting.
  
  
  RESULTS
  Carotid stenting and endarterectomy was primarily successful without residual stenosis > 30% in each patient without the occurrence of stroke or death. In 18 follow-up examinations (neurological assessment including duplex sonography) of 13 patients (13 follow-up examinations after 30 days, 5 after 6 months) no relevant restenosis and no stroke occurred.
  
  
  CONCLUSIONS
  As of yet, carotid stenting was a safe procedure. Due to the small number of patients a definitive conclusion can not be drawn.
authors.affiliation: Institut für Röntgendiagnostik, Universitätsklinikum Regensburg.
authors.forename: J
authors.initials: J
authors.lastname: Link
authors.forename: C
authors.initials: C
authors.lastname: Manke
authors.forename: L
authors.initials: L
authors.lastname: Rosin
authors.forename: I
authors.initials: I
authors.lastname: Borisch
authors.forename: I
authors.initials: I
authors.lastname: Töpel
authors.forename: M
authors.initials: M
authors.lastname: Horn
authors.forename: S
authors.initials: S
authors.lastname: Mann
authors.forename: K W
authors.initials: KW
authors.lastname: Jauch
authors.forename: U
authors.initials: U
authors.lastname: Bogdahn
authors.forename: S
authors.initials: S
authors.lastname: Feuerbach
authors.forename: P
authors.initials: P
authors.lastname: Kasprzak
mesh_terms: D015901:Angiography, Digital Subtraction; D000800:Angioplasty, Balloon; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D002340:Carotid Artery Diseases / Q000175:diagnosis / Q000628:therapy; D016894:Endarterectomy, Carotid; D005500:Follow-Up Studies; D006801:Humans; D018579:Patient Selection; D010865:Pilot Projects; D011292:Premedication; D011446:Prospective Studies; D015607:Stents