title: Synthesis and in vitro cytotoxicity of 2-alkylaminosubstituted quinoline derivatives.
abstract: Eight 2-alkylaminosubstituted 5,8-dimethoxy-4-methylquinolines and nine 2-alkylaminosubstituted or 2,6-disubstituted 4-methylquinoline-5,8-diones were synthesized and evaluated in vitro cytotoxicity against four human cancer cell lines (HOP62, SK-OV-3, HCT15 and SF295).
authors.affiliation: College of Pharmacy, Chungbuk National University, Cheongju, Korea. medchem@trut.chungbuk.ac.kr
authors.forename: H
authors.initials: H
authors.lastname: Lee
authors.forename: J
authors.initials: J
authors.lastname: Lee
authors.forename: S S
authors.initials: SS
authors.lastname: Hong
authors.forename: S I
authors.initials: SI
authors.lastname: Yang
authors.forename: S H
authors.initials: SH
authors.lastname: Jung
authors.forename: Y
authors.initials: Y
authors.lastname: Jahng
authors.forename: J
authors.initials: J
authors.lastname: Cho
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D006801:Humans; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology; D013329:Structure-Activity Relationship; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D011804:Quinolines