title: Adverse reaction to amoxicillin: a case report.
abstract: Penicillin is the drug that most often leads to allergic reactions and anaphylaxis. The incidence of adverse events triggered by penicillins is believed to be between 1% and 10%. Up to one-tenth of these episodes are life-threatening, with the most serious reactions occurring in patients with no history of allergy. The case of a 5 year, 3 month-old female who had a severe allergic reaction to amoxicillin prior to a dental appointment is described. The literature on penicillin hypersensitivity is reviewed and recommendations for management of an allergic reaction in the pediatric dental office are discussed.
authors.affiliation: Department of Orthodontics and Pediatric Dentistry, University of Michigan, School of Dentistry, USA. marcio@umich.edu
authors.forename: M A
authors.initials: MA
authors.lastname: da Fonseca
mesh_terms: D000658:Amoxicillin / Q000009:adverse effects*; D000707:Anaphylaxis / Q000139:chemically induced / Q000628:therapy; D000799:Angioedema / Q000139:chemically induced / Q000628:therapy; D019072:Antibiotic Prophylaxis / Q000009:adverse effects*; D002675:Child, Preschool; D017742:Dental Care for Chronically Ill / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology* / Q000628:therapy; D004638:Emergency Treatment; D005260:Female; D006330:Heart Defects, Congenital; D006801:Humans; D010406:Penicillins / Q000009:adverse effects*
chemical_list: D010406:Penicillins; D000658:Amoxicillin