title: Cell and molecular biological challenges of ICSI: ART before science?
abstract: Authors discuss the possible genetic and cell biological risks to offspring conceived by ICSI in relation to the lack of fundamental research using relevant animal models.
authors.affiliation: Center for Women's Health, Oregon Regional Primate Research Center, Oregon Health Sciences University, Beaverton, USA.
authors.forename: G
authors.initials: G
authors.lastname: Schatten
authors.forename: L
authors.initials: L
authors.lastname: Hewitson
authors.forename: C
authors.initials: C
authors.lastname: Simerly
authors.forename: P
authors.initials: P
authors.lastname: Sutovsky
authors.forename: G
authors.initials: G
authors.lastname: Huszar
mesh_terms: D032761:Animal Experimentation; D000818:Animals; D004622:Embryo, Mammalian / Q000502:physiology; D005260:Female; D005306:Fertilization / Q000502:physiology*; D030342:Genetic Diseases, Inborn; D006801:Humans; D007248:Infertility, Male; D008297:Male; D011247:Pregnancy; D018570:Risk Assessment; D012449:Safety; D012941:Social Responsibility; D020554:Sperm Injections, Intracytoplasmic