title: Chronic urticaria in children: expanding the "autoimmune kaleidoscope".
abstract: Most cases of chronic urticaria (CU) are considered idiopathic. It has recently been accepted that autoimmunity plays a critical role in the pathogenesis of CU in some of these patients. Although urticaria is common in the pediatric population, the knowledge regarding CU-associated autoimmunity is very limited. We describe the association of CU with a wide spectrum of clinical and laboratory autoimmune disorders in 2 children and emphasize the concept that CU is another manifestation of the "autoimmune kaleidoscope."
authors.affiliation: Pediatric Allergy and Clinical Immunology Unit, Department of Pediatrics, Edith Wolfson Medical Center, Holon 58100 Israel. roydalal@hotmail.com
authors.forename: I
authors.initials: I
authors.lastname: Dalal
authors.forename: A
authors.initials: A
authors.lastname: Levine
authors.forename: E
authors.initials: E
authors.lastname: Somekh
authors.forename: A
authors.initials: A
authors.lastname: Mizrahi
authors.forename: A
authors.initials: A
authors.lastname: Hanukoglu
mesh_terms: D000293:Adolescent; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000276:immunology; D002648:Child; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D014581:Urticaria / Q000175:diagnosis* / Q000276:immunology