title: Structure-based design of novel bicyclic nonpeptide inhibitors for the src SH2 domain.
authors.affiliation: ARIAD Pharmaceuticals, Inc., 26 Landsdowne Street, Cambridge, Massachusetts 02139-4234, USA. william.shakespeare@ariad.com
authors.forename: W C
authors.initials: WC
authors.lastname: Shakespeare
authors.forename: R S
authors.initials: RS
authors.lastname: Bohacek
authors.forename: M D
authors.initials: MD
authors.lastname: Azimioara
authors.forename: K J
authors.initials: KJ
authors.lastname: Macek
authors.forename: G P
authors.initials: GP
authors.lastname: Luke
authors.forename: D C
authors.initials: DC
authors.lastname: Dalgarno
authors.forename: M H
authors.initials: MH
authors.lastname: Hatada
authors.forename: X
authors.initials: X
authors.lastname: Lu
authors.forename: S M
authors.initials: SM
authors.lastname: Violette
authors.forename: C
authors.initials: C
authors.lastname: Bartlett
authors.forename: T K
authors.initials: TK
authors.lastname: Sawyer
mesh_terms: D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D015195:Drug Design; D005454:Fluorescence Polarization; D008958:Models, Molecular; D013329:Structure-Activity Relationship; D018909:src Homology Domains
chemical_list: D001643:Bridged Bicyclo Compounds