[Cavum lymphoma in a hemophilic patient with AIDS].
Intermediate and highly malignant non-Hodgkin and primary central nervous system lymphomas are marker diseases for AIDS. Cavum and oropharynx involvement by these tumors is uncommon. Although there are few cases reported in the literature, these may be primary localizations of the tumor. We present a hemophilic HIV+ patient with non-Hodgkin lymphoma of the cavum. The histologic diagnosis was high-grade, pleomorphic, centroblastic lymphoma. The patient was treated with chemotherapy plus intrathecal chemotherapy and highly active antiretroviral therapy (HAART). His evolution has been excellent. One year after diagnosis, the patient is asymptomatic with no evidence of residual tumor, and responding well to HAART.
Corti
M
M
Instituto de Investigaciones Hematológicas, Academia Nacional de Medicina y Fundación de la Hemofilia, Buenos Aires. mcorti@roche.com.ar
Villafañe
M F
MF
Cermelj
M
M
Candela
M
M
Pérez Blanco
R
R
Tezanos Pinto
M
M
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed