Oral focal epithelial hyperplasia in a howler monkey (Alouatta fusca).
Oral focal epithelial hyperplasia is a rare and seldom reported disease in animals and humans induced by a papillomavirus. The present report is the first description of this disease in a Neotropical primate, a howler monkey (Alouatta fusca). The diagnosis was based on gross and microscopic findings. The generic papillomavirus antigen was identified by immunohistochemistry and was found not to be related to any human papillomavirus DNA tested by in situ hybridization. This virus is probably a specific papillomavirus of the howler monkey (HMPV).
Sá
L R
LR
Departamento de Patologia, Faculdade de Medicina Veterinária e Zootecnia, Cidade Universitária, São Paulo, Brasil. liliansa@osite.com.br
DiLoreto
C
C
Leite
M C
MC
Wakamatsu
A
A
Santos
R T
RT
Catão-Dias
J L
JL
D000508:Alouatta; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001938:Brazil; D017809:Fatal Outcome; D017573:Focal Epithelial Hyperplasia / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D017403:In Situ Hybridization / Q000662:veterinary; D008297:Male; D008992:Monkey Diseases / Q000473:pathology*; D027383:Papillomaviridae / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000473:pathology / Q000662:veterinary*; D011817:Rabbits
D000956:Antigens, Viral