title: Angiosarcoma arising on rhinophyma.
abstract: We report an 82-year-old man who presented with a tumor which had developed over the previous year on the right nasal ala of a rhinophyma. Histopathological, immunohistochemical, and electron microscopic study confirmed the diagnosis of angiosarcoma on the head and neck. He was treated with radiotherapy of the tumor and cervical adenopathy, which developed later. The possible etiological and pathogenetic role of lymphedema due to inflammatory flares of rosacea on the nose is discussed, together with the histological and immunohistochemical data leading to the diagnosis of this tumor.
authors.affiliation: Department of Dermatology and Venereology, Cátedra de Dermatología Facultad de Medicina Campus Universitario Teatinos 29010 Malaga, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Gallardo
authors.forename: R J
authors.initials: RJ
authors.lastname: Bosch
authors.forename: L
authors.initials: L
authors.lastname: Vidal
authors.forename: B
authors.initials: B
authors.lastname: Cabra
authors.forename: A B
authors.initials: AB
authors.lastname: Rodrigo
authors.forename: M V
authors.initials: MV
authors.lastname: De Galvez
authors.forename: E
authors.initials: E
authors.lastname: Herrera
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000209:etiology* / Q000532:radiotherapy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009669:Nose Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000532:radiotherapy; D012224:Rhinophyma / Q000150:complications* / Q000175:diagnosis