Cutaneous angiosarcoma arising in a gouty tophus: report of a unique case and a review of foreign material-associated angiosarcomas.
Rare cases of angiosarcoma have been reported to arise in the setting of retained foreign material or in association with arteriovenous fistulae. No previous case of angiosarcoma, or any other malignancy, has been reported to arise with a gouty tophus. We present a case of an 86-year-old man with a high-grade angiosarcoma that arose within a long-standing tophus.
Folpe
A L
AL
Department of Pathology and Laboratory Medicine, Emory University Medical Center, Atlanta, USA.
Johnston
C A
CA
Weiss
S W
SW
D000368:Aged; D000369:Aged, 80 and over; D015210:Arthritis, Gouty / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D005547:Foreign Bodies / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D006394:Hemangiosarcoma / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000378:metabolism; D012878:Skin Neoplasms / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D014527:Uric Acid / Q000378:metabolism; D014841:von Willebrand Factor / Q000378:metabolism
D019408:Platelet Endothelial Cell Adhesion Molecule-1; D014841:von Willebrand Factor; D014527:Uric Acid