[Factors interfering with CRP assay (from the manufacturer's perspective)].
Recently, there have been many highly sensitive methods for CRP assay. However, there are also many factors that interfere with CRP assay. We are taking measures to avoid interference due to factors such as, myeloma protein, rheumatoid factor, lipaemia(a substance similar to detergent in the capillary tube, etc). Currently CRP assay methods which are not influenced by these factors are available. However, other unknown factors that interfere with CRP assay have become apparent. We think that these are peculiar to the immunoassay. We are taking measures to identify these interference factors and resolve the problem. In the following, we will explain some experiments that will protect our re-agent from these interference factors.
Tomiyama
R
R
Development Department, Iatron Laboratories, INC., Tokyo.
D002097:C-Reactive Protein / Q000032:analysis*; D004345:Drug Industry; D006801:Humans; D006949:Hyperlipidemias; D007118:Immunoassay / Q000379:methods*; D009194:Myeloma Proteins; D009391:Nephelometry and Turbidimetry / Q000379:methods; D010783:Photometry / Q000379:methods; D011933:Reagent Kits, Diagnostic; D015203:Reproducibility of Results; D012217:Rheumatoid Factor; D012680:Sensitivity and Specificity
D009194:Myeloma Proteins; D011933:Reagent Kits, Diagnostic; D002097:C-Reactive Protein; D012217:Rheumatoid Factor