title: [Neurochemical organization of the brain reinforcing systems].
abstract: Modern concepts of neurophysiological mechanisms of the brain reinforcing systems are reviewed from A.A. Ukhtomsky's concept of dominanta. The brain mesocorticolimbic system was shown to play a key role in functioning of the brain reinforcing systems. Morphological and neurochemical organisation of this system determining the emotional sphere, was studied. The dopamine system was found to be the main neurochemical tool of the mesocorticolimbic system. Other transmitters, neuromodulators, and hormones play a regulatory role in the latter. The data obtained corroborate the authors' concept of fluctuating emotional gradient.
authors.affiliation: St. Petersburg State University, Russia.
authors.forename: P D
authors.initials: PD
authors.lastname: Shabanov
authors.forename: A D
authors.initials: AD
authors.lastname: Nozdrachev
authors.forename: A A
authors.initials: AA
authors.lastname: Lebedev
authors.forename: V A
authors.initials: VA
authors.lastname: Lebedev
mesh_terms: D000818:Animals; D001921:Brain / Q000254:growth & development / Q000378:metabolism* / Q000502:physiology*; D004298:Dopamine / Q000378:metabolism; D004644:Emotions / Q000502:physiology*; D051381:Rats; D012054:Reinforcement, Psychology; D012934:Social Isolation
chemical_list: D004298:Dopamine