[Investigation on the stimulation effect of polypyrrole film on rat hepatic cells].
Poypyrrole(PPy) films were prepared at 1 x 10(-3) mA/cm2 electropolymerization current density on indium-tin oxide(ITO)substrate. The PPy films were well-distributed, translucent, stable and insoluble. Moreover, they can be sterilized by steam disinfection. Rat hepatic cells were cultured on these films. The results show that PPy films have good biocompatibility and they can accelerate cell growth under electrical stimulation. The cells on PPy films reach the largest cell density earlier than the cells on tissue culture polystyrene(TCPS). Furthermore, rat hepatic cells can generate on PPy films. The cells on PPy films grow faster and enter logarithmic growth phase earlier than those on TCPS.
Jiang
Y
Y
Department of Biomedical Engineering, Southeast University, Nanjing.
Yuan
C W
CW
Li
Y H
YH
Pu
Y P
YP
Wu
L
L
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004558:Electric Stimulation; D022781:Hepatocytes / Q000187:drug effects* / Q000502:physiology; D011108:Polymers / Q000494:pharmacology*; D011758:Pyrroles / Q000494:pharmacology*; D051381:Rats
D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole