title: [Effect of antioxidant therapy on indicators of free radical activity in workers at risk of lead exposure].
abstract: The authors administered to 36 workers exposed to lead, for four weeks the preparation Prolong which contains vitamin C, vitamin E, beta-carotene, selenium, zinc and chromium and investigated the effect on indicators of free radicals. A statistically significant increase of the following occurred: superoxide dismutase (p < 0.001), glutathione peroxidase (p < 0.01), an increase of the total antioxidant capacity (p < 0.01) and an increase of uricaemia (p < 0.05). Based on these results the authors consider supplementation with antioxidants indicated in workers exposed to lead.
authors.affiliation: Klinika pracovního LF UK a FN, Plzen.
authors.forename: V
authors.initials: V
authors.lastname: Machartová
authors.forename: J
authors.initials: J
authors.lastname: Racek
authors.forename: J
authors.initials: J
authors.lastname: Kohout
authors.forename: V
authors.initials: V
authors.lastname: Senft
authors.forename: L
authors.initials: L
authors.lastname: Trefil
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use*; D005609:Free Radicals / Q000378:metabolism*; D005979:Glutathione Peroxidase / Q000032:analysis; D006801:Humans; D007855:Lead Poisoning / Q000378:metabolism / Q000517:prevention & control*; D008315:Malondialdehyde / Q000032:analysis; D008875:Middle Aged; D009784:Occupational Diseases / Q000378:metabolism / Q000517:prevention & control*; D013482:Superoxide Dismutase / Q000032:analysis
chemical_list: D000975:Antioxidants; D005609:Free Radicals; D008315:Malondialdehyde; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase