title: Physical activity, functional limitations, and disability in older adults.
abstract: OBJECTIVE
  To explore initially how low levels of physical activity influence lower body functional limitations in participants of the Longitudinal Study of Aging. Changes in functional limitations are used subsequently to predict transitions in the activities of daily living/instrumental activities of daily living (ADL/IADL) disability, thus investigating a potential pathway for how physical activity may delay the onset of ADL/IADL disability and, thus, prolong independent living.
  
  
  METHODS
  Analysis of a complex sample survey of US civilian, noninstitutionalized population aged 70 years and older in 1984, with repeated interviews in 1986, 1988, and 1990.
  
  
  METHODS
  Analyses concentrated on 5151 men and women targeted for interview at all four LSOA interviews.
  
  
  METHODS
  Characteristics used in analyses: gender, age, level of physical activity, comorbid conditions including the presence of hypertension, diabetes, arthritis, and atherosclerotic heart disease, levels of functional limitations, and ADL/IADL disability.
  
  
  RESULTS
  Transitional models provide evidence that older adults who have varying levels of disability and who report at least a minimal level of physical activity experience a slower progression in functional limitations (OR = .45, P < .001 for severe vs less severe limitations). This low level of physical activity, through its influence on changes in functional limitations, is shown to slow the progression of ADL/IADL disability.
  
  
  CONCLUSIONS
  Results from analyses provide supporting evidence that functional limitations can mediate the effect that physical activity has on ADL/IADL disability. These results contribute further to the increasing data that seem to suggest that physical activity can reduce the progression of disability in older adults.
authors.affiliation: Department of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina 27157, USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Miller
authors.forename: W J
authors.initials: WJ
authors.lastname: Rejeski
authors.forename: B A
authors.initials: BA
authors.lastname: Reboussin
authors.forename: T R
authors.initials: TR
authors.lastname: Ten Have
authors.forename: W H
authors.initials: WH
authors.lastname: Ettinger
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D001161:Arteriosclerosis / Q000150:complications; D001168:Arthritis / Q000150:complications; D015897:Comorbidity; D048909:Diabetes Complications; D006233:Persons with Disabilities / Q000706:statistics & numerical data*; D018450:Disease Progression; D015444:Exercise; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D006973:Hypertension / Q000150:complications; D016015:Logistic Models; D008137:Longitudinal Studies; D008297:Male; D011237:Predictive Value of Tests; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology