Real-time ultrasonographically guided transvaginal instillation for intraperitoneal chemotherapy of ovarian carcinoma.
OBJECTIVE
To describe the techniques we have developed to instill chemotherapeutic agents into the pelvic cavity using real-time transvaginal ultrasonographic guidance.


METHODS
This was used for intraperitoneally administered chemotherapy in 11 patients with ovarian carcinoma.


RESULTS
A total of 38 instillations were done in these patients. The average time for instillation was 23.9 min. No adhesions were associated with this chemotherapy. As for complications, hematuria occurred during 2 (5.3%) instillations. No other complications were observed.


CONCLUSIONS
Real-time ultrasonographically guided transvaginal intraperitoneal chemotherapy can be performed without any catheter systems. This is a safe, reliable, convenient, repeatable, and inexpensive procedure.
Yamaguchi
H
H
Department of Obstetrics and Gynecology, Ise City Hospital, Ise, Mie, Japan. yama@ise.hospitalunet.ocn.ne.jp
Ito
M
M
Toyoda
N
N
D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D018282:Cystadenocarcinoma, Mucinous / Q000188:drug therapy; D018284:Cystadenocarcinoma, Serous / Q000188:drug therapy; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D007725:Krukenberg Tumor / Q000188:drug therapy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D010529:Peritoneal Cavity / Q000000981:diagnostic imaging*; D014463:Ultrasonography; D014621:Vagina
D000970:Antineoplastic Agents