Detection of hepatitis G virus (HGV) RNA and antibodies to the HGV envelope protein E2 in a cohort of hemodialysis patients.
An analysis of the evolution of hepatitis G virus (HGV) infection markers was performed for a cohort of 58 hemodialyzed patients. During follow-up (4.88 +/- 0.42 years), a group of these patients cleared their antibodies against the envelope protein E2 with (4 of 29 cases; 13.8%) or without (9 of 29 cases; 31%) the reappearance of viremia. This finding implies a temporally limited protection in patients previously infected with HGV.
Pérez-Gracia
T
T
Servicio de Microbiología, Hospital Universitario Puerto Real, Cádiz, Spain.
Galán
F
F
Girón-González
J A
JA
Lozano
A
A
Benavides
B
B
Fernández
E
E
Rodríguez-Iglesias
M
M
D000328:Adult; D000368:Aged; D015331:Cohort Studies; D005260:Female; D018067:Flaviviridae / Q000276:immunology / Q000302:isolation & purification* / Q000502:physiology; D006508:Hepatitis Antibodies / Q000097:blood*; D006525:Hepatitis, Viral, Human / Q000175:diagnosis / Q000821:virology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012367:RNA, Viral / Q000097:blood*; D006435:Renal Dialysis; D014759:Viral Envelope Proteins / Q000276:immunology*; D014766:Viremia
D006508:Hepatitis Antibodies; D012367:RNA, Viral; D014759:Viral Envelope Proteins; C107619:glycoprotein E2, GB virus C