[The production of antihypertensive peptides in beta-casein proteolysis].
Antihypertensive peptides were obtained after the proteolysis of beta-casein by starter cells Lactococcus lactis ssp. lactis and lactococci with pepsin or fromase. The peptides have shown the effect as inhibitors of angiotensin-converting enzyme. The strongest action the peptide obtained after the proteolysis of beta-casein by synergic action of lactococci with pepsin has shown. It demonstrates a capability of formation of such peptides directly in milk products during their making and maturation under the action of proteolytic system of lactic acid bacteria and milk clothing proteases.
Iukalo
V H
VH
Ivan Pului Technical University, Ternopil.
Luhovyĭ
B L
BL
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000378:metabolism*; D000959:Antihypertensive Agents / Q000378:metabolism*; D002364:Caseins / Q000187:drug effects* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D013294:Lactococcus lactis / Q000201:enzymology; D008970:Molecular Weight; D009842:Oligopeptides / Q000096:biosynthesis / Q000187:drug effects*; D010434:Pepsin A / Q000494:pharmacology; D010447:Peptide Hydrolases / Q000494:pharmacology*
D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002364:Caseins; D009842:Oligopeptides; C010980:hippuryl-histidyl-leucine; D010447:Peptide Hydrolases; D010434:Pepsin A