[Chlamydial laryngitis: clinical picture and amixine treatment].
Chlamydia trachomatis DNA was detected by PCR in 12 patients with continuously recurrent catarrhal pharyngolaryngitis. These included 9 males and 3 females whose age ranged 16 to 72 years. All the patients were found to have degrees II-III alpha- and g-INF deficiencies. The interferon inducer amixine in combination with sumamed was used in the treatment of patients with chlamydial laryngitis. After treatment, there was a significant improvement in two thirds of patients. The pain syndrome was relieved, hoarseness diminished, and the laryngoscopic and microlaryngostroboscopic picture and interferon status became normal. Control studies showed no Ch. trachomatis in this group of patients. Despite positive changes in the course of the disease, the control study again detected Ch. trachomatis in 4 patients, which required repeated treatment courses.
Demchenko
E V
EV
Ivanchenko
G F
GF
Prozorovskaia
K N
KN
Bocharov
A F
AF
Boĭkova
N E
NE
D000293:Adolescent; D000328:Adult; D000368:Aged; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007369:Interferon Inducers / Q000627:therapeutic use*; D007827:Laryngitis / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D013994:Tilorone / Q000627:therapeutic use*
D007369:Interferon Inducers; D013994:Tilorone