title: Percutaneous transpedicular vertebroplasty with PMMA: operative technique and early results. A prospective study for the treatment of osteoporotic compression fractures.
abstract: Vertebroplasty-percutaneous cement augmentation of osteoporotic vertebrae is an efficient procedure for the treatment of painful vertebral fractures. From a prospectively monitored series of 70 patients with 193 augmented vertebrae for osteoporotic and metastatic lesions, we analysed a group of 17 patients suffering from back pain due to osteoporotic fractures. The reinforcement of 45 vertebral bodies in these patients led to a significant and lasting pain reduction (P < 0.01 ). The presented technique is useful, as, in one session, at least four injections can be performed when required, allowing the prophylactic reinforcement of adjacent vertebrae as well. The use of a low-viscosity polymethyl methacrylate (PMMA) in combination with a non-ionic liquid contrast dye provides a reliable and safe procedure. Extraosseous cement leakage was seen in 20% of the interventions; however, none of them had clinical sequelae.
authors.affiliation: Department of Orthopaedic Surgery, Spine Service, Inselspital, University of Bern, Switzerland. paul.heini@insel.ch
authors.forename: P F
authors.initials: PF
authors.lastname: Heini
authors.forename: B
authors.initials: B
authors.lastname: Wälchli
authors.forename: U
authors.initials: U
authors.lastname: Berlemann
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001843:Bone Cements; D001864:Bone Wires; D005260:Female; D006801:Humans; D007267:Injections; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications*; D019904:Polymethyl Methacrylate / Q000008:administration & dosage*; D011446:Prospective Studies; D016103:Spinal Fractures / Q000601:surgery*; D013904:Thoracic Vertebrae
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate