Updated sequence information and proposed nomenclature for bla(TEM) genes and their promoters.
The nucleotide sequences of 59 bla(TEM) genes encoding inhibitor-resistant TEM enzymes showed great genetic variability and were associated with different types of promoters. These findings led us to suggest an updated bla(TEM) gene nomenclature based on the origin of the bla(TEM) gene (bla(TEM-1A), bla(TEM-1B), bla(TEM-1C), bla(TEM-1D), bla(TEM-1E), and bla(TEM-1F)) and the promoter type.
Leflon-Guibout
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V
Microbiology Department, Hôpital Ambroise-Paré, Université Paris V, 92100 Boulogne-Billancourt, France.
Heym
B
B
Nicolas-Chanoine
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M
D014644:Genetic Variation; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic / Q000235:genetics*; D016415:Sequence Alignment; D009626:Terminology as Topic; D001618:beta-Lactamases / Q000145:classification / Q000235:genetics*
D001618:beta-Lactamases