title: Fluoride release in vitro from a resin-modified glass ionomer after exposure to NaF solutions and toothpastes.
abstract: The aims of the present investigation were: (i) to study the release of fluoride from a resin-modified glass ionomer cement (Vitremer) after exposing ("recharging") the material with NaF toothpastes and NaF solutions with different fluoride concentrations, and (ii) to study the effect of covering the material with a sealant layer (glaze) in this respect. Totally 160 specimens were made, which were placed in water for 13 weeks to receive a low fluoride release value. The specimens were then randomly divided into 10 groups with 16 discs each. Five of the groups were exposed once a day for 7 days to one of the following fluoride agents: 0.05, 0.2 or 2% NaF solutions and slurries of two NaF toothpastes (Acta and Pepsodent). The other five groups received the same treatment twice a day. All treatments had a recharging effect. However, the 2% NaF solution resulted in significantly more fluoride release than the other solutions and toothpastes. Treatment twice a day gave higher total release than once a day, but the difference were only significant for the 0.2 and 2% NaF solutions. With glaze material covering the specimens, almost no fluoride release was observed. However, when the glaze was removed, a burst of fluoride occurred.
authors.affiliation: Department of Cariology, Faculty of Odontology, Göteborg University, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Posada
authors.forename: C G
authors.initials: CG
authors.lastname: Emilson
authors.forename: D
authors.initials: D
authors.lastname: Birkhed
mesh_terms: D000704:Analysis of Variance; D003188:Composite Resins / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D005459:Fluorides / Q000032:analysis / Q000737:chemistry*; D005899:Glass Ionomer Cements / Q000737:chemistry*; D066298:In Vitro Techniques; D008422:Materials Testing / Q000379:methods / Q000706:statistics & numerical data; D011897:Random Allocation; D012969:Sodium Fluoride / Q000494:pharmacology*; D012996:Solutions; D013997:Time Factors; D014100:Toothpastes / Q000494:pharmacology*
chemical_list: D003188:Composite Resins; D005899:Glass Ionomer Cements; D012996:Solutions; D014100:Toothpastes; C084550:Vitremer; D012969:Sodium Fluoride; D005459:Fluorides