Incidence, location, and diagnostic evaluation of metastatic bone disease.
Metastatic carcinoma is the most common malignancy of bone. The clinical presentation of patients with skeletal metastasis is variable. When asked to evaluate a patient with a pathologic lesion or unexplained bone pain, the orthopedic surgeon should follow a logical sequence of steps in evaluating the patient with suspected metastasis to optimize care and avoid complications. In the majority of cases, a systematic approach to the patient with skeletal metastasis leads to the correct diagnosis.
Hage
W D
WD
Department of Orthopaedic Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Aboulafia
A J
AJ
Aboulafia
D M
DM
D014408:Biomarkers, Tumor / Q000097:blood; D001706:Biopsy; D001859:Bone Neoplasms / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000556:secondary*; D006801:Humans; D015994:Incidence; D009382:Neoplasms, Unknown Primary / Q000175:diagnosis
D014408:Biomarkers, Tumor