Dendritic cells and their involvement in atherosclerosis.
Dendritic cells constitute a unique family of cells able to induce primary immune responses. Over the past decade, immunologists have been increasingly preoccupied with dendritic cells and dendritic cells are now seen as a panacea for vaccine development, tumour immunotherapy and a host of other immunological applications. The recent finding of dendritic cells accumulating in atherosclerotic lesions should stimulate investigation of their contributions to atherogenesis and their potential use in anti-atherosclerosis therapies.
Bobryshev
Y V
YV
Lipid Metabolism Unit, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA. bobryshev@molbio.mgh.harvard.edu
D000818:Animals; D001158:Arteries / Q000166:cytology / Q000276:immunology; D001161:Arteriosclerosis / Q000209:etiology* / Q000276:immunology* / Q000628:therapy; D003713:Dendritic Cells / Q000145:classification / Q000276:immunology*; D004195:Disease Models, Animal; D006801:Humans; D007167:Immunotherapy