title: Magnetic resonance imaging in the assessment of urologic disease: an all-in-one approach.
abstract: The aim of this study was to evaluate an "all-in-one" MR procedure to examine the kidneys, the renal vascular supply and renal perfusion, and the urinary tract. In 64 patients (58 with urologic disease and 6 healthy volunteers), MR was performed including: (a) T1- and T2-weighted imaging; (b) 3D contrast-enhanced MR angiography (MRA), including the renal arteries, renal veins, as well as renal perfusion; and (c) 3D contrast-enhanced MR urography (MRU) in the coronal and sagittal plane. For the latter, low- and high-resolution images were compared. Prior to gadolinium injection, 0.1 mg/kg body weight of furosemide was administered intravenously. The results were compared with correlative imaging modalities (ultrasonography, intravenous urography, CT), ureterorenoscopy and/or surgical-pathologic findings. Visualization of the renal parenchyma, the vascular supply, and the collecting system was adequate in all cases, both in nondilated and in dilated systems and irrespective of the renal function. One infiltrating urothelial cancer was missed; there was one false-positive urothelial malignancy. Different MR techniques can be combined to establish an all-in-one imaging modality in the assessment of diseases which affect the kidneys and urinary tracts. Continuous refinement of the applied MR techniques and further improvements in spatial resolution is needed to expand the actual imaging possibilities and to create new tracts and challenges in the MR evaluation of urologic disease.
authors.affiliation: Department of Radiology, University Hospitals, Catholic University of Leuven, Belgium.
authors.forename: G A
authors.initials: GA
authors.lastname: Verswijvel
authors.forename: R H
authors.initials: RH
authors.lastname: Oyen
authors.forename: H P
authors.initials: HP
authors.lastname: Van Poppel
authors.forename: H
authors.initials: H
authors.lastname: Goethuys
authors.forename: B
authors.initials: B
authors.lastname: Maes
authors.forename: J
authors.initials: J
authors.lastname: Vaninbrouckx
authors.forename: H
authors.initials: H
authors.lastname: Bosmans
authors.forename: G
authors.initials: G
authors.lastname: Marchal
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004232:Diuretics / Q000008:administration & dosage; D005260:Female; D005665:Furosemide / Q000008:administration & dosage; D019786:Gadolinium DTPA / Q000008:administration & dosage; D006801:Humans; D007275:Injections, Intravenous; D007668:Kidney / Q000473:pathology; D018810:Magnetic Resonance Angiography / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D012077:Renal Artery / Q000473:pathology; D012082:Renal Veins / Q000473:pathology; D015203:Reproducibility of Results; D014513:Ureter / Q000473:pathology; D001743:Urinary Bladder / Q000473:pathology; D014570:Urologic Diseases / Q000175:diagnosis*
chemical_list: D004232:Diuretics; D005665:Furosemide; D019786:Gadolinium DTPA