Effects of theophylline on exercise indices in a patient with chronotropic incompetence.
Several investigators have documented the successful use of oral sustained-release theophylline in treating symptomatic bradycardia and sick sinus syndrome. This paper reports a case of chronotropic incompetence in which specific exercise indices, including the chronotropic response index, were used to measure the therapeutic efficacy of theophylline.
Dixon
W C
WC
Department of Medicine, Brooke Army Medical Center, San Antonio, Texas 78234, USA.
Bauch
T D
TD
D001919:Bradycardia / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D003692:Delayed-Action Preparations; D017079:Exercise Tolerance / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012804:Sick Sinus Syndrome / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D013806:Theophylline / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
D003692:Delayed-Action Preparations; D014665:Vasodilator Agents; D013806:Theophylline