Cortical MRI findings associated with rapid correction of hyponatremia.
The authors describe two patients with clinical manifestations of the osmotic demyelination syndrome (ODS) and unusual MRI findings of gadolinium-enhancing peripheral cortical abnormalities. They propose that these represent extrapontine manifestations of ODS because neither patient had a notable hypoxic-ischemic insult. Recognizing this imaging appearance is important because prognosis in ODS may be less uniformly grim than for hypoxia-ischemia.
Calakos
N
N
Department of Neurology, University of California, San Francisco, USA. calakos@itsa.ucsf.edu
Fischbein
N
N
Baringer
J R
JR
Jay
C
C
D000328:Adult; D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013997:Time Factors