title: The production of superantigenic exotoxins by coagulase-negative staphylococci isolated from human skin lesions.
abstract: We examined the production of superantigenic exotoxins in 136 coagulase-negative staphylococci isolated from various skin lesions in humans using a reversed passive latex agglutination test (Denka Seiken). As a control we examined the same in 50 Staphylococcus aureus strains isolated from non-infective skin ulcers in humans. Of the 136 strains of coagulase negative-staphylococci, 9 (6.6%) produced one or more identifiable exotoxins. In contrast, 21 (42%) out of the 50 S. aureus strains produced one or more identifiable exotoxins (P<0.01).
authors.affiliation: Department of Dermatology, Okayama University Medical School, Shikata-cho 2-5-1, 700-8558, Okayama, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Akiyama
authors.forename: O
authors.initials: O
authors.lastname: Yamasaki
authors.forename: J
authors.initials: J
authors.lastname: Tada
authors.forename: J
authors.initials: J
authors.lastname: Arata
mesh_terms: D003030:Coagulase / Q000032:analysis*; D005098:Exotoxins / Q000096:biosynthesis*; D006801:Humans; D012871:Skin Diseases / Q000382:microbiology*; D013210:Staphylococcus / Q000201:enzymology / Q000302:isolation & purification* / Q000378:metabolism*; D018089:Superantigens / Q000096:biosynthesis*
chemical_list: D003030:Coagulase; D005098:Exotoxins; D018089:Superantigens