title: Sialographic images of pathological changes in the mouse parotid gland.
abstract: In order to correlate pathological changes of mouse parotid glands with their sialographic images, we conducted studies on mice with known pathological changes: mice with Stensen's duct ligated, NZB mice with a systemic auto-immune disease, and aged mice. The sialographic images were found to be specific for the pathological changes: The glands after ligation of Stensen's duct were characterized by dilated, large excretory ducts with a reduced system of peripheral ducts; the glands of NZB mice showed lobular leakage of the contrast medium from small excretory ducts; and the glands of aged mice showed a great reduction in the ductal system. It is concluded that sialography yields useful information on the pathological changes of the ductal systems in the mouse parotid gland.
authors.affiliation: Department of Dental Radiology, Tokyo Medical and Dental University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Domon
authors.forename: T
authors.initials: T
authors.lastname: Kurabayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Shiga
mesh_terms: D000375:Aging / Q000502:physiology; D000818:Animals; D008026:Ligation; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008814:Mice, Inbred NZB; D010306:Parotid Gland / Q000000981:diagnostic imaging* / Q000473:pathology*; D018987:Salivary Ducts; D012796:Sialography; D012859:Sjogren's Syndrome / Q000000981:diagnostic imaging / Q000473:pathology