title: Histopathological survey of neoplasms in flat-coated retrievers, 1990 to 1998.
abstract: Over the period from March 1990 to December 1998, veterinary surgeons in general practice were invited to submit tissues suspected of being neoplastic which had been removed from flat-coated retrievers. When possible, pedigree details were obtained from the owners. In addition, data were collected from flat-coated retrievers known to have suffered from a neoplastic condition and for which a histopathological report was available. A total of 1023 submissions was obtained from 782 dogs. These included 165 non-neoplastic lesions (16 per cent), 447 benign samples (44 per cent) and 411 malignant samples (40 per cent). Soft tissue sarcomas accounted for 55 per cent of the malignant samples (26 per cent of all tumour samples and 22 per cent of all submissions) with 63 per cent of them being diagnosed as undifferentiated. Carcinomas accounted for 20 per cent of malignant samples (8 per cent of all submissions). Of the benign tumours, cutaneous histiocytoma was the most common diagnosis (48 per cent of benign tumours, 25 per cent of all tumours and 21 per cent of all submissions).
authors.affiliation: Department of Clinical Veterinary Medicine, University of Cambridge, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Morris
authors.forename: D E
authors.initials: DE
authors.lastname: Bostock
authors.forename: E F
authors.initials: EF
authors.lastname: McInnes
authors.forename: T M
authors.initials: TM
authors.lastname: Hoather
authors.forename: J M
authors.initials: JM
authors.lastname: Dobson
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000453:epidemiology* / Q000473:pathology*; D004285:Dogs; D004739:England / Q000453:epidemiology; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary; D008297:Male; D009369:Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary*; D010375:Pedigree; D012509:Sarcoma / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary; D012878:Skin Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary; D012983:Soft Tissue Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary