Assignment of transcription factor NFAT5 to human chromosome 16q22.1, murine chromosome 8D and porcine chromosome 6p1.4 and comparison of the polyglutamine domains.
To date, transcription factors of the NFAT family (nuclear factors of activated T cells) have been described for mouse and man. Recently, we mapped the human NFAT5 gene to chromosome 16 by PCR using DNA from hybrid cell lines. Here we report the exact position of the human gene between D16S496 and WI5254 within the 16q22.1 subband, the localization of the murine gene at chromosome 8D, and the identification and mapping of the porcine counterpart to chromosome 6p1.4.
Hebinck
A
A
Universität Lübeck, Institut für Humangenetik, Lübeck, Germany.
Dalski
A
A
Engel
H
H
Mattei
M
M
Hawken
R
R
Schwinger
E
E
Zühlke
C
C
D000818:Animals; D001483:Base Sequence; D002885:Chromosomes, Human, Pair 16 / Q000235:genetics*; D003001:Cloning, Molecular; D004268:DNA-Binding Proteins / Q000737:chemistry* / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D051379:Mice; D008969:Molecular Sequence Data; D050778:NFATC Transcription Factors; D010455:Peptides / Q000737:chemistry* / Q000235:genetics; D020161:Physical Chromosome Mapping; D017434:Protein Structure, Tertiary; D021101:Radiation Hybrid Mapping; D013552:Swine / Q000235:genetics*; D014157:Transcription Factors / Q000737:chemistry* / Q000235:genetics*
D004268:DNA-Binding Proteins; D050778:NFATC Transcription Factors; D010455:Peptides; D014157:Transcription Factors; C097188:polyglutamine