title: Study on the decomposition products of thiadiazinthione and their anticancer properties.
abstract: Study of the anticancer properties of thirty-four 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazin-2-thione derivatives has been carried out by using cytotoxicity assays against HeLa, HT-29 and Hep G2 cells. The decomposition products of thiadiazinthione 1 m have been studied and their anticancer properties evaluated.
authors.affiliation: Laboratorio de Síntesis Orgánica, Facultad de Qímica, Universidad de La Habana, Cuba.
authors.forename: R
authors.initials: R
authors.lastname: Pérez
authors.forename: H
authors.initials: H
authors.lastname: Rodríguez
authors.forename: E
authors.initials: E
authors.lastname: Pérez
authors.forename: M
authors.initials: M
authors.lastname: Suárez
authors.forename: O
authors.initials: O
authors.lastname: Reyes
authors.forename: L J
authors.initials: LJ
authors.lastname: González
authors.forename: A
authors.initials: A
authors.lastname: López de Cerain
authors.forename: O
authors.initials: O
authors.lastname: Ezpelata
authors.forename: C
authors.initials: C
authors.lastname: Pérez
authors.forename: C
authors.initials: C
authors.lastname: Ochoa
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D019073:HT29 Cells; D006367:HeLa Cells; D006801:Humans; D008114:Liver Neoplasms, Experimental / Q000188:drug therapy; D013829:Thiadiazines / Q000737:chemistry* / Q000494:pharmacology*; D013871:Thiones / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D013829:Thiadiazines; D013871:Thiones