title: Fungicidal and herbicidal activities of berberine related alkaloids.
abstract: The 23 quaternary and tertiary protoberberines related to berberine were tested for in vitro and/or in vivo fungicidal and herbicidal activities. Among the compounds tested, there was some activity observed with some of only the protoberberinium salts, but not sufficiently strong or broad spectrum for agrochemical use. From the structure-activity point of view, some features can be pointed out.
authors.affiliation: Dow Argo Sciences LLC, Indianapolis, Indiana 46268, USA. K-iwasa@kobepharma-u.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Iwasa
authors.forename: M
authors.initials: M
authors.lastname: Moriyasu
authors.forename: B
authors.initials: B
authors.lastname: Nader
mesh_terms: D001600:Berberine Alkaloids / Q000737:chemistry* / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects*; D005659:Fungicides, Industrial / Q000737:chemistry / Q000494:pharmacology*; D006540:Herbicides / Q000737:chemistry / Q000494:pharmacology*; D019684:Magnoliopsida / Q000187:drug effects; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D010944:Plants / Q000382:microbiology*; D006109:Poaceae / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: D001600:Berberine Alkaloids; D005659:Fungicides, Industrial; D006540:Herbicides