Contaminated drinking water in one town manifesting as an outbreak of cryptosporidiosis in another.
In early 1992 we identified an outbreak of cryptosporidiosis in Oregon and sought to identify and control its source. We used a series of studies to identify risk factors for illness: (i) a case-control study among employees of a long-term-care facility (LTCF); (ii) a matched case-control study of the general community; (iii) a cohort study of wedding attendees; and (iv) a cross-sectional survey of the general community. Drinking Talent water was associated with illness in the LTCF (OR = 22.7, 95 % CI = 2.7-1009.0), and in the community (matched OR = 9.5, 95% CI 2.3-84.1). Drinking Talent water was associated with illness only among non-Talent residents who attended the wedding (P < 0.001) and in the community (RR = 6.5, 95 % CI 3.3-12.9). The outbreak was caused by contaminated municipal water from Talent in the absence of a discernible outbreak among Talent residents, suggesting persons exposed to contaminated water may develop immunity to cryptosporidiosis.
McAnulty
J M
JM
Oregon Health Division, Center for Disease Prevention and Epidemiology, Portland 97232, USA.
Keene
W E
WE
Leland
D
D
Hoesly
F
F
Hinds
B
B
Stevens
G
G
Fleming
D W
DW
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D003457:Cryptosporidiosis / Q000453:epidemiology*; D003458:Cryptosporidium / Q000302:isolation & purification*; D003967:Diarrhea / Q000469:parasitology*; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007223:Infant; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D009922:Oregon / Q000453:epidemiology; D014871:Water Microbiology; D014881:Water Supply