title: [Effects of icarrin on secretive function of cultured granulosa and adrenal cortical cells of rats].
abstract: Icarrin was added to cultured cells and the hormones in culture fluid were determined after 3 hours of incubation. The results showed that icarrin (30-1000 micrograms/L) could promote the estradiol production of granulosa cells. The most effective concentration was 100 micrograms/L. Icarrin also exerted a stimulatory effect on corticosterone production at the highest dosage (1000 micrograms/L).
authors.affiliation: Hebei Medical University, Shijiazhuang.
authors.forename: F
authors.initials: F
authors.lastname: Li
authors.forename: E
authors.initials: E
authors.lastname: Li
authors.forename: Z
authors.initials: Z
authors.lastname: Lu
authors.forename: S
authors.initials: S
authors.lastname: Song
authors.forename: X
authors.initials: X
authors.lastname: Wang
authors.forename: X
authors.initials: X
authors.lastname: Tong
mesh_terms: D000302:Adrenal Cortex / Q000166:cytology / Q000378:metabolism*; D000818:Animals; D002478:Cells, Cultured; D003345:Corticosterone / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism*; D005260:Female; D005419:Flavonoids / Q000494:pharmacology*; D006107:Granulosa Cells / Q000378:metabolism*; D051381:Rats
chemical_list: D005419:Flavonoids; D004958:Estradiol; C056599:icariin; D003345:Corticosterone