Mapping of architectonic subdivisions in the macaque monkey, with emphasis on parieto-occipital cortex.
The intraparietal sulcus (IPS) of the macaque monkey contains numerous areas associated with different aspects of cortical function, including motor control as well as visual, somatosensory, vestibular, and possibly auditory processing. This study focuses largely on the architectonic organization of areas within and near the IPS, but also examines remaining portions of the hemisphere with which the IPS is interconnected. We charted the location of up to 72 architectonically distinct areas plus numerous architectonic zones in individuals over a region covering most of the cortical hemisphere. Identified cortical subdivisions (areas plus zones) were represented on computationally generated flat maps in relation to gyral and sulcal geography, thereby facilitating the analysis of consistent as well as variable aspects of the sizes and relative positions of subdivisions across animals. Using myelin and Nissl stains, plus immunohistochemical staining with the SMI-32 antibody, 17 architectonic subdivisions were identified that are largely or entirely contained in the intraparietal and parieto-occipital sulci. This includes four newly identified zones: a heavily myelinated lateral occipitoparietal zone, termed LOP; a strongly SMI-32 immunoreactive zone termed 7t (near the tip of the IPS); plus medial and lateral subdivisions (VIPm and VIPl) of ventral intraparietal area (VIP), which was previously regarded as an anatomically homogeneous area. Within the superior temporal sulcus, we identified a densely myelinated zone termed the dorso-posterior subdivision of the medial superior temporal area (MSTdp) that bordered middle temporal area (MT). We charted the extent of numerous other architectonically defined subdivisions throughout the cortical hemisphere by using criteria largely based on previous studies, but in some instances involving revised or expanded identification criteria.
Lewis
J W
JW
California Institute of Technology, Pasadena, California 16825, USA. james@mcw.edu
Van Essen
D C
DC
D000818:Animals; D001931:Brain Mapping; D005260:Female; D006179:Gyrus Cinguli / Q000166:cytology / Q000502:physiology; D007091:Image Processing, Computer-Assisted; D008252:Macaca fascicularis / Q000033:anatomy & histology* / Q000502:physiology; D008297:Male; D009044:Motor Cortex / Q000166:cytology / Q000502:physiology; D009778:Occipital Lobe / Q000166:cytology* / Q000502:physiology; D010296:Parietal Lobe / Q000166:cytology* / Q000502:physiology; D017397:Prefrontal Cortex / Q000166:cytology / Q000502:physiology; D013003:Somatosensory Cortex / Q000166:cytology / Q000502:physiology; D013702:Temporal Lobe / Q000166:cytology / Q000502:physiology; D014793:Visual Cortex / Q000166:cytology / Q000502:physiology