title: Immediate results of the 'Bioglis' valve use in the surgical treatment of Ebstein's anomaly.
abstract: OBJECTIVE
  The optimum material for heart valves bioprostheses remains in dispute. We have created a biological valve made from hepatic Glisson's capsule and named 'Bioglis'. Experimental studies have shown the major characteristics of the 'Bioglis' valve to be equivalent to, and in some cases superior to, those of traditional valves made from xenopericardial tissue. We present the first experience of the 'Bioglis' valve use in surgical treatment of Ebstein's anomaly.
  
  
  METHODS
  Twelve consecutive patients (age range: 7-48 years) with Ebstein's anomaly who underwent surgery between 1997 and 1999 were reviewed. A 'Bioglis' valve was implanted in all cases; two patients underwent repeat surgery because of incompetence of a previously implanted xenopericardial valve. The 'Bioglis' valve was formed, using a flexible frame, from the hepatic Glisson's capsule of bull calves. Short-term results at between two and 10 weeks after surgery were analyzed. Valvular function of the implanted 'Bioglis' valve was monitored by echocardiography.
  
  
  RESULTS
  The implanted 'Bioglis' valve diameter ranged from 31 to 33 mm. There were no in-hospital deaths or complications. Echocardiography showed good function of the bioprostheses. Consequent peak and mean pressure gradients across the biological valve ranged from 3 to 7 mmHg and from 1.2 to 2.3 mmHg, respectively. Valve insufficiency occurred in one patient, but was minimal.
  
  
  CONCLUSIONS
  Preliminary results with the 'Bioglis' support our recommendation of this new biological valve for clinical use.
authors.affiliation: Bakoulev Scientific Center for Cardiovascular Surgery RAMS, Moscow, Russia.
authors.forename: L A
authors.initials: LA
authors.lastname: Bockeria
authors.forename: I I
authors.initials: II
authors.lastname: Kagramanov
authors.forename: I V
authors.initials: IV
authors.lastname: Kokshenev
authors.forename: M R
authors.initials: MR
authors.lastname: Chiaureli
authors.forename: A A
authors.initials: AA
authors.lastname: Gadzhiev
authors.forename: I N
authors.initials: IN
authors.lastname: Mitina
authors.forename: S B
authors.initials: SB
authors.lastname: Zaets
authors.forename: M Sh
authors.initials: MSh
authors.lastname: Ruzmetov
mesh_terms: D000293:Adolescent; D000328:Adult; D001705:Bioprosthesis; D002648:Child; D004437:Ebstein Anomaly / Q000601:surgery*; D018618:Echocardiography, Doppler, Color; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008875:Middle Aged; D011474:Prosthesis Design; D016896:Treatment Outcome