title: Antiretroviral therapy of HIV-1 infection: established treatment strategies and new therapeutic options.
abstract: Recently, studies have shown that non-nucleoside reverse transcriptase inhibitors, such as efavirenz or nevirapine, in combination with two nucleoside analogues have an antiretroviral potency comparable to protease inhibitor containing regimens. Triple combination therapy that includes a non-nucleoside reverse transcriptase inhibitor can therefore be regarded as an effective alternative first-line treatment of HIV-1 infection.
authors.affiliation: National Centre in HIV Epidemiology and Clinical Research, Level 2, 376 Victoria Street, NSW 2010, Sydney, Australia. gkaufmann@nchecr.unsw.edu.au
authors.forename: G R
authors.initials: GR
authors.lastname: Kaufmann
authors.forename: D A
authors.initials: DA
authors.lastname: Cooper
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000627:therapeutic use; D015497:HIV-1; D006801:Humans; D018894:Reverse Transcriptase Inhibitors / Q000627:therapeutic use; D016879:Salvage Therapy
chemical_list: D019380:Anti-HIV Agents; D017320:HIV Protease Inhibitors; D018894:Reverse Transcriptase Inhibitors