title: Decisionally impaired persons in research: refining the proposed refinements.
abstract: Amid the ethical debate about consent to research involving cognitively impaired subjects, author cautions against creating barriers to acceptable research and provides criteria by which guidelines should be developed.
authors.affiliation: Department of Clinical Bioethics, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: E G
authors.initials: EG
authors.lastname: DeRenzo
mesh_terms: D026724:Ethical Review; D028744:Ethics Committees, Research; D004992:Ethics, Medical; D035082:Federal Government; D033161:Government Regulation; D006805:Human Experimentation; D006801:Humans; D007258:Informed Consent; D016743:Mental Competency; D001523:Mental Disorders; D033242:Minors; D033281:Nontherapeutic Human Experimentation; D018579:Patient Selection; D035842:Research Subjects; D018570:Risk Assessment; D036302:Therapeutic Human Experimentation; D014481:United States