Gender-specific differences in temporomandibular retrodiscal tissues of the goat.
Healthy, adult, male and female goat temporomandibular retrodiscal tissues were characterized to determine if biochemical differences existed between the genders. RNA concentrations were not different between male and female retrodiscal tissues; however, the DNA concentration in female retrodiscal tissues was 82% greater than in male retrodiscal tissues. Collagen concentrations were significantly greater in male retrodiscal tissues, and this was reflected in significant gender differences of type I and III collagen concentrations. More specifically, male temporomandibular retrodiscal tissues contained 70% more type I collagen and 119% more type III collagen when compared to female retrodiscal tissues. These differences in collagens and DNA reflect a gender difference in temporomandibular retrodiscal tissue composition that underlies divergent biomechanical and neurophysiological properties.
Mariotti
A
A
Section of Periodontology, College of Dentistry, The Ohio State University, Columbus 43210-1241, USA. mariotti.3@osu.edu
Rumpf
D
D
Malakhova
O
O
Cooper
B
B
D000818:Animals; D001696:Biomechanical Phenomena; D002358:Cartilage, Articular / Q000737:chemistry; D003094:Collagen / Q000032:analysis; D003238:Connective Tissue / Q000737:chemistry; D004247:DNA / Q000032:analysis; D004548:Elasticity; D005260:Female; D006041:Goats; D008297:Male; D012313:RNA / Q000032:analysis; D012727:Sex Characteristics; D013704:Temporomandibular Joint / Q000737:chemistry*
D012313:RNA; D003094:Collagen; D004247:DNA