title: [Influence of single-photon emission scan duration measured with the  ECAT ART PET scanner].
abstract: OBJECTIVE
  The aim was to study the influence of single-photon-transmission scan duration in 3D-PET on the quantitative values of attenuation coefficients and noise in transmission images and of activity concentrations and noise in attenuation corrected emission images of thorax phantom- and patient data.
  
  
  METHODS
  Using dual collimated Cs-137 singles transmission sources (E gamma = 662 KeV, A = 2* 614 MBq) on an ECAT ART tomograph series of transmission scans of a thorax phantom were acquired pre- and post-injection of 18F. 17 patients underwent two transmission scans. The scan time of the short transmission was chosen according to the results of the phantom studies (noise of Poisson statistics less than 4%). Transmission and attenuation corrected emission images were evaluated with respect to estimated linear attenuation coefficients, noise and specific activities in organs.
  
  
  RESULTS
  The phantom studies reveal little variation of the estimated linear attenuation coefficients as a function of scan duration. The estimates of the attenuation coefficients are found to be 1% lower than the expected values for pre- and up to 6.5% lower for post-injection transmissions. The noise level in the transmission images increases as expected for Poisson data. The noise level in the attenuation corrected emission images shows only little increase with decreasing transmission scan time whereas it is strongly influenced by a variation of emission scan time. In patient studies, less than 3% difference was found in the estimated linear attenuation coefficients as well as in the activity concentrations between short (pre or post-injection) and long transmission scans. The noise levels in transmission and emission images are 1% (pre-injection) and 4% (post-injection) higher for short transmission scans.
  
  
  CONCLUSIONS
  Due to the high photon flux, single photon transmission offers good clinical performance with significantly reduced transmission scan durations (< 2 min/bed in pre-, < 4 min/bed in post-injection transmission).
authors.affiliation: Abteilung für Nuklearmedizin, Radiologischen Klinik der Universitätskliniken des Saarlandes, Homburg/Saar, Deutschland. raasch@med-rz.uni-sb.de
authors.forename: A
authors.initials: A
authors.lastname: Schaefer
authors.forename: S
authors.initials: S
authors.lastname: Kremp
authors.forename: D
authors.initials: D
authors.lastname: Hellwig
authors.forename: C
authors.initials: C
authors.lastname: Alexander
authors.forename: C M
authors.initials: CM
authors.lastname: Kirsch
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging; D018279:Carcinoma, Signet Ring Cell / Q000000981:diagnostic imaging; D002588:Cesium Radioisotopes; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D008297:Male; D009369:Neoplasms / Q000000981:diagnostic imaging*; D009382:Neoplasms, Unknown Primary / Q000000981:diagnostic imaging; D019047:Phantoms, Imaging; D012044:Regression Analysis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging; D013909:Thorax; D014055:Tomography, Emission-Computed / Q000295:instrumentation* / Q000379:methods
chemical_list: D002588:Cesium Radioisotopes