title: A case of pencil core granuloma with an unusual temporal profile.
abstract: The patient is a 47-year-old female with a bluish tumor resembling malignant melanoma at the macroscopic level on the medial aspect of her left big toe. The patient had crushed a pencil with this toe about 30 years previously and, since then, a bluish lesion had been present. About 15 years ago, the lesion had suddenly increased in size over the course of a few months. Subsequently, the size of the lesion had not changed noticeably. Ultrasonography, but not magnetic resonance imaging was a helpful preoperative examination to distinguish the lesion from malignant melanoma. The excised lesion contained a piece of material that resembled pencil lead and bluish mud. X-ray microanalysis of the lead-like material revealed that its composition was similar to that of pencil lead. Histologic examination showed features of foreign-body reaction, except for necrotic change and few histiocytes.
authors.affiliation: Department of Dermatology, Oita Medical University, Oita, Japan. HATANO@oita-med.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Hatano
authors.forename: Y
authors.initials: Y
authors.lastname: Asada
authors.forename: S
authors.initials: S
authors.lastname: Komada
authors.forename: S
authors.initials: S
authors.lastname: Fujiwara
authors.forename: S
authors.initials: S
authors.lastname: Takayasu
mesh_terms: D005260:Female; D005533:Foot Dermatoses / Q000139:chemically induced / Q000473:pathology*; D015745:Granuloma, Foreign-Body / Q000139:chemically induced / Q000473:pathology*; D006801:Humans; D007854:Lead / Q000009:adverse effects; D008875:Middle Aged; D012871:Skin Diseases / Q000139:chemically induced / Q000473:pathology*; D013997:Time Factors
chemical_list: D007854:Lead