[Immune disorders in periodic disease].
The examination of 404 patients with periodic disease (301 with uncomplicated form and 104 with amyloidosis complication) has detected decreased functional activity of T-lymphocytes and their suppressor subpopulation, their subnormal quantity. There was a rise in T-helper/T-suppressor index, level of B- and 0-lymphocytes, sensitivity to the renal antigen. Colchicin therapy stopped the attacks and stimulated T-suppressor activity. Combined treatment with tactivin is proposed.
Karagezian
K G
KG
Nazaretian
E E
EE
Zavgorodniaia
A M
AM
Ovnanian
K O
KO
D000293:Adolescent; D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology*; D010505:Familial Mediterranean Fever / Q000276:immunology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology*