title: Biologic therapy.
abstract: Biologic therapy has evolved as a fourth treatment option for patients with melanoma and other malignancies. Interrelated advances in molecular diagnostics and gene therapy techniques will further accelerate therapeutic advances in this new arena. A variety of biologic therapeutic options available to the patient with high risk melanoma are reviewed.
authors.affiliation: Division of Plastic and Reconstructive Surgery, Magee Womens Hospital, University of Pittsburgh Medical Center, University of Pittsburgh Cancer Institute, Pennsylvania 15213, USA.
authors.forename: H
authors.initials: H
authors.lastname: Edington
authors.forename: S
authors.initials: S
authors.lastname: Agarwala
authors.forename: J M
authors.initials: JM
authors.lastname: Kirkwood
mesh_terms: D000911:Antibodies, Monoclonal / Q000276:immunology / Q000627:therapeutic use; D001691:Biological Therapy / Q000379:methods* / Q000639:trends; D016207:Cytokines / Q000276:immunology; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D016898:Interferon-alpha / Q000627:therapeutic use; D007371:Interferon-gamma / Q000627:therapeutic use; D007378:Interleukins / Q000627:therapeutic use; D007978:Levamisole / Q000627:therapeutic use; D008222:Lymphokines / Q000502:physiology; D008545:Melanoma / Q000276:immunology / Q000628:therapy*; D009000:Monocytes / Q000276:immunology / Q000502:physiology; D009163:Mycobacterium bovis / Q000276:immunology; D012878:Skin Neoplasms / Q000276:immunology / Q000628:therapy*
chemical_list: D000911:Antibodies, Monoclonal; D016207:Cytokines; D016898:Interferon-alpha; D007378:Interleukins; D008222:Lymphokines; D007978:Levamisole; D007371:Interferon-gamma