Translation initiation: insect virus RNAs rewrite the rule book.
Picorna-like insect virus RNAs direct an unorthodox form of translation initiation at a non-AUG-related codon, without involvement of initiator tRNA. This seems to involve a special type of mRNA pseudoknot structure which allows bypassing of the usual P-site-dependent mechanism.
McCarthy
J E
JE
Department of Biomolecular Sciences, UMIST, Manchester M60 1QD, UK. j.mccarthy@umist.ac.uk
D000818:Animals; D003062:Codon; D007304:Insect Viruses / Q000235:genetics*; D014176:Protein Biosynthesis / Q000235:genetics*; D012367:RNA, Viral / Q000502:physiology*
D003062:Codon; D012367:RNA, Viral