title: [Individualized drug therapy--need for improvement].
abstract: The lack of dose adjustment to the individual needs of a patient is a major cause for the substantial difference between the efficacy of therapies established in large trials and the therapeutic results obtained in everyday practice (reduced effectiveness). In addition, these differences affect drug safety and ultimately also costs. Hence strategies to maintain good compliance and to avoid incompatibilities, drug interactions and adverse events should be applied whenever drugs are prescribed. This supplement compiles different techniques and measures which may support health professionals in reaching these goals.
authors.affiliation: Abteilung Innere Medizin VI, Universität Heidelberg. walter_emil_haefeli@med.uni-heidelberg.de
authors.forename: W E
authors.initials: WE
authors.lastname: Haefeli
mesh_terms: D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D011307:Drug Prescriptions / Q000592:standards*; D019317:Evidence-Based Medicine / Q000592:standards*; D005858:Germany; D006801:Humans; D010347:Patient Care Planning / Q000592:standards; D010349:Patient Compliance; D010601:Pharmacology, Clinical / Q000592:standards*; D011364:Professional Practice / Q000592:standards*; D013557:Switzerland