[Diagnosis by electron microscopy of recessive dystrophic epidermolysis bullosa].
Inherited epidermolysis bullosa (EB) includes a number of distinctive diseases that are characterized by the presence of fragile skin and the tendency to develop blisters and erosions. The current classification separates the types of EB on the basis of the ultrastructural level of the blisters. The electron microscopy is very important for the diagnosis and in the recessive dystrophic EB shows that the lamina densa forms the roof of the blister and that the number of anchoring fibrils are absent or reduced. We present the case of a 30 year old woman with a diagnosis of recessive dystrophic EB diagnosed by electron microscopy.
Glorio
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División Dermatología, Hospital de Clínicas José de San Martín. glohaa@yahoo.com
Solari
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Woscoff
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D000328:Adult; D001768:Blister / Q000473:pathology; D016108:Epidermolysis Bullosa Dystrophica / Q000235:genetics / Q000473:pathology*; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D010375:Pedigree