[Effects of icarrin on secretive function of cultured granulosa and adrenal cortical cells of rats].
Icarrin was added to cultured cells and the hormones in culture fluid were determined after 3 hours of incubation. The results showed that icarrin (30-1000 micrograms/L) could promote the estradiol production of granulosa cells. The most effective concentration was 100 micrograms/L. Icarrin also exerted a stimulatory effect on corticosterone production at the highest dosage (1000 micrograms/L).
Li
F
F
Hebei Medical University, Shijiazhuang.
Li
E
E
Lu
Z
Z
Song
S
S
Wang
X
X
Tong
X
X
D000302:Adrenal Cortex / Q000166:cytology / Q000378:metabolism*; D000818:Animals; D002478:Cells, Cultured; D003345:Corticosterone / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism*; D005260:Female; D005419:Flavonoids / Q000494:pharmacology*; D006107:Granulosa Cells / Q000378:metabolism*; D051381:Rats
D005419:Flavonoids; D004958:Estradiol; C056599:icariin; D003345:Corticosterone