title: Infant lung function, bronchial responsiveness and the development of asthma.
abstract: Infants who wheeze are likely to have narrowed or overly compliant airways rather than atopy. After around 3 years of age, airway responsiveness and atopy are associated with the development of wheeze and the diagnosis of asthma. Anti- or proinflammatory genes are likely to be responsible for at least part of the predisposition to wheeze seen in older children, but further studies are needed to clarify this situation.
authors.affiliation: Department of Paediatrics, Faculty of Medicine and Dentistry, Princess Margaret Hospital for Children, University of Western Australia, Nedlands, Perth.
authors.forename: P
authors.initials: P
authors.lastname: Le Souëf
mesh_terms: D001249:Asthma / Q000235:genetics / Q000276:immunology* / Q000503:physiopathology; D001980:Bronchi / Q000502:physiology*; D006801:Humans; D007223:Infant; D008168:Lung / Q000502:physiology*