Steroid receptors and metastatic potential in endometrial cancers.
The relative overexpression of oestrogen receptor (ER)-alpha exon 5 splicing variant (ER-alpha E5SV), ER-beta and progesterone receptor (PR) from B (PR-B) without transcriptional repression by PR from A (PR-A) might be related to the metastatic potential and partially cause deviation from sex steroidal dependency in endometrial cancers.
Fujimoto
J
J
Department of Obstetrics and Gynaecology, Gifu University School of Medicine, 40, Tsukasa-machi, 500-8705, Gifu City, Japan.
Sakaguchi
H
H
Aoki
I
I
Tamaya
T
T
D016889:Endometrial Neoplasms / Q000378:metabolism*; D047628:Estrogen Receptor alpha; D047629:Estrogen Receptor beta; D005091:Exons; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D012333:RNA, Messenger / Q000378:metabolism; D011960:Receptors, Estrogen / Q000378:metabolism*; D011980:Receptors, Progesterone / Q000378:metabolism
D047628:Estrogen Receptor alpha; D047629:Estrogen Receptor beta; D012333:RNA, Messenger; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone