Genetic research as therapy: implications of "gene therapy" for informed consent.
Authors argue that characterization of gene transfer research as "gene therapy" has compromised informed consent in the current environment of regulatory exceptions, routinized consent, fostered therapeutic misconceptions, and oversold research.
Churchill
L R
LR
Department of Social Medicine, University of North Carolina, Chapel Hill, USA.
Collins
M L
ML
King
N M
NM
Pemberton
S G
SG
Wailoo
K A
KA
D026683:Advisory Committees; D026686:Beneficence; D030881:Disclosure; D028744:Ethics Committees, Research; D004992:Ethics, Medical; D035082:Federal Government; D036281:Genetic Research; D015316:Genetic Therapy; D033161:Government Regulation; D006805:Human Experimentation; D006801:Humans; D007258:Informed Consent; D026684:Personal Autonomy; D035842:Research Subjects; D018570:Risk Assessment; D036302:Therapeutic Human Experimentation; D035502:Trust; D014481:United States