title: Silent spread of dengue and dengue haemorrhagic fever to Coimbatore and Erode districts in Tamil Nadu, India, 1998: need for effective surveillance to monitor and control the disease.
abstract: Dengue fever (DF) or dengue haemorrhagic fever (DHF) has not previously been reported in Coimbatore and Erode districts in Tamil Nadu in India. In 1998, 20 hospitalized cases of fever tested positive for dengue virus IgM and/or IgG antibodies. All of them had dengue-compatible illness, and at least four had DHF. Two of them died. Sixteen cases were below 10 years of age. The cases were scattered in 15 distantly located villages and 5 urban localities that had a high Aedes aegypti population. Although the incidence of dengue-like illness has not increased recently, almost 89% (95/107) of samples from healthy persons in the community tested positive for dengue IgG antibodies. The study showed that dengue has been endemic in the area, but was not suspected earlier. A strong laboratory-based surveillance system is essential to monitor and control DF/DHF.
authors.affiliation: National Institute of Communicable Diseases, Delhi, India.
authors.forename: J
authors.initials: J
authors.lastname: Singh
authors.forename: N
authors.initials: N
authors.lastname: Balakrishnan
authors.forename: M
authors.initials: M
authors.lastname: Bhardwaj
authors.forename: P
authors.initials: P
authors.lastname: Amuthadevi
authors.forename: E G
authors.initials: EG
authors.lastname: George
authors.forename: K
authors.initials: K
authors.lastname: Subramani
authors.forename: K
authors.initials: K
authors.lastname: Soundararajan
authors.forename: N C
authors.initials: NC
authors.lastname: Appavoo
authors.forename: D C
authors.initials: DC
authors.lastname: Jain
authors.forename: R L
authors.initials: RL
authors.lastname: Ichhpujani
authors.forename: R
authors.initials: R
authors.lastname: Bhatia
authors.forename: J
authors.initials: J
authors.lastname: Sokhey
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000097:blood / Q000453:epidemiology* / Q000517:prevention & control*; D003716:Dengue Virus / Q000276:immunology; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D011159:Population Surveillance / Q000379:methods; D019595:Severe Dengue / Q000097:blood / Q000453:epidemiology / Q000517:prevention & control
chemical_list: D000914:Antibodies, Viral