title: An epidemic of congenital rubella in Barbados.
abstract: Rubella and congenital rubella syndrome (CRS) are preventable, but epidemics of rubella and CRS are not infrequent in the Caribbean and other developing countries. As a result of a surveillance system initiated after an epidemic of rubella in the Barbadian population in 1996, cases of CRS were identified and investigated. A total of seven cases of CRS were proven to be rubella IgM-positive. The infants were found to have a mean birthweight of 2587 g and a mean gestational age of 38 weeks. The clinical course, complications and outcome of those infants were documented and the cost of acute hospital care for each patient was also recorded. Cataracts in four infants, congenital heart disease in three and central nervous system abnormalities in five were the major clinical abnormalities. In four infants, two or more clinical systems were affected. The combined total hospital stay was 105 days (mean 15, range 0-44). A national effort to immunize all those at risk and a strict surveillance programme are essential to prevent future epidemics. This would lead to a significant reduction in the number of cases of rubella and CRS and could effect substantial savings in the national health budget.
authors.affiliation: Department of Paediatrics, Queen Elizabeth Hospital, St Michael, Barbados, West Indies. cedwards@sunbeach.net
authors.forename: M A
authors.initials: MA
authors.lastname: St John
authors.forename: S
authors.initials: S
authors.lastname: Benjamin
mesh_terms: D001460:Barbados / Q000453:epidemiology; D004196:Disease Outbreaks; D005260:Female; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D012409:Rubella / Q000453:epidemiology; D012410:Rubella Syndrome, Congenital / Q000453:epidemiology*