title: Lack of agreement between tonometric and gastric juice partial carbon dioxide tension.
abstract: STATEMENT OF FINDINGS: Our goal was to compare measurement of tonometered saline and gastric juice partial carbon dioxide tension (PCO2). In this prospective observational study, 112 pairs of measurements were simultaneously obtained under various hemodynamic conditions, in 15 critical care patients. Linear regression analysis showed a significant correlation between the two methods of measuring PCO2 (r(2) = 0.43; P < 0.0001). However, gastric juice PCO2 was systematically higher (mean difference 51 mmHg). The 95% limits of agreement were 315 mmHg and the dispersion increased as the values of PCO2 increased. Tonometric and gastric juice PCO2 cannot be used interchangeably. Gastric juice PCO2 measurement should be interpreted with caution.
authors.affiliation: Clínica Bazterrica, Capital Federal, Argentina. adeo@infovia.com.ar
authors.forename: A
authors.initials: A
authors.lastname: Dubin
authors.forename: J
authors.initials: J
authors.lastname: Badie
authors.forename: S
authors.initials: S
authors.lastname: Fernandez
authors.forename: E
authors.initials: E
authors.lastname: Estenssoro
authors.forename: H
authors.initials: H
authors.lastname: Canales
authors.forename: G
authors.initials: G
authors.lastname: Bordoli
authors.forename: F
authors.initials: F
authors.lastname: Pálizas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015982:Bias; D001784:Blood Gas Analysis / Q000379:methods*; D002245:Carbon Dioxide / Q000032:analysis* / Q000097:blood; D015986:Confounding Factors, Epidemiologic; D005260:Female; D005745:Gastric Acidity Determination; D005750:Gastric Juice / Q000737:chemistry*; D005753:Gastric Mucosa / Q000098:blood supply* / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007511:Ischemia / Q000175:diagnosis* / Q000378:metabolism*; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods*; D011379:Prognosis; D011446:Prospective Studies; D012965:Sodium Chloride
chemical_list: D002245:Carbon Dioxide; D012965:Sodium Chloride