title: Laparoscopic excision of accessory spleen.
abstract: BACKGROUND
  Laparoscopic splenectomy has become an accepted procedure in the management of several hematologic diseases. Less clear is the effectiveness of laparoscopic excision of accessory spleens after initial splenectomy in the management of recurrent hematologic disease. We report here our early experience of this technique.
  
  
  METHODS
  All patients who underwent laparoscopic excision of accessory spleens (LEAS) after initial splenectomy were reviewed for preoperative studies, technical success, and effects on either platelet count or hemoglobin level.
  
  
  RESULTS
  In 5 patients LEAS was attempted. Two patients had initial open splenectomies, and 3 had initial laparoscopic splenectomies. Hematologic diagnoses were immune thrombocytopenic purpura (3), chronic lymphocytic leukemia-induced thrombocytopenia (1), and autoimmune hemolytic anemia (1). All patients underwent preoperative damaged red blood cell scintigraphy, which demonstrated functioning splenic tissue, and abdominal computed tomography scans, which demonstrated a nodule in 4 of 5 patients. LEAS was technically successful in 4 patients, with the 1 failure also being the patient in whom the computed tomography scan could not demonstrate the accessory spleen. However, only 2 of the 4 patients after LEAS had durable hematologic responses to surgery, despite follow-up damaged red blood cell scintigraphy showing no residual functioning splenic tissue.
  
  
  CONCLUSIONS
  LEAS can be technically successful when the accessory spleen is demonstrated on both damaged red blood cell scintigraphy and computed tomography scan; therefore, adequate visualization in both studies is required. However, hematologic response to excision may be less effective than with the initial splenectomy. Further study is needed to determine the causes of these outcomes.
authors.affiliation: Divisions of General Surgery and Hematology/Oncology, Henry Ford Hospital, Detroit, Michigan 48202-2689, USA.
authors.forename: V
authors.initials: V
authors.lastname: Velanovich
authors.forename: M
authors.initials: M
authors.lastname: Shurafa
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000601:surgery; D004912:Erythrocytes; D005500:Follow-Up Studies; D006402:Hematologic Diseases / Q000601:surgery; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D010535:Laparoscopy; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications; D010976:Platelet Count; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000601:surgery; D011860:Radiography, Abdominal; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012008:Recurrence; D013154:Spleen / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery; D013156:Splenectomy; D013921:Thrombocytopenia / Q000209:etiology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D006454:Hemoglobins; D019275:Radiopharmaceuticals