title: [The clinical application of a new method for sealing the cut surface of lung using the photopolymerized synthetic bioabsorbable hydrogel (Advaseal)].
abstract: We report a case of 67-years-old male, who suffered right upper lobectomy for primary lung cancer. The upper-middle interlobar surface of right lung was incomplete interlobe. Many air leakages were noted in the cut surface of upper-middle interlobe during the sealing test. We sealed this cut surface of upper-middle interlobe by using the photopolymerized synthetic bioabsorbable hydrogel (Advaseal). Air leakage was not noted during the sealing test, and no leakage was not noted after operation. We have observed no biological toxicity (such as cytotoxicity, hemolytic toxicity, systemic toxicity or mutagenic toxicity) by using Advaseal. The new photopolymerized synthetic bioabsorbable hydrogel (Advaseal) is a effective sealant against pulmonary air leaks in the cut surface of the lung.
authors.affiliation: Department of Surgery, Jikei University School of Medicine, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Takagi
authors.forename: T
authors.initials: T
authors.lastname: Akiba
authors.forename: M
authors.initials: M
authors.lastname: Masubuchi
authors.forename: K
authors.initials: K
authors.lastname: Yoshida
authors.forename: Y
authors.initials: Y
authors.lastname: Yamazaki
mesh_terms: D000368:Aged; D006801:Humans; D020100:Hydrogels / Q000627:therapeutic use*; D008171:Lung Diseases / Q000517:prevention & control; D008175:Lung Neoplasms / Q000601:surgery; D008297:Male; D011013:Pneumonectomy / Q000379:methods*; D016156:Respiratory Tract Fistula / Q000517:prevention & control; D014014:Tissue Adhesives / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D020100:Hydrogels; D014014:Tissue Adhesives