title: The course of Tourette's disorder: a literature review.
abstract: With the goal of evaluating the available literature on the course of Tourette's disorder, we conducted a systematic literature search through electronic databases for pertinent scientific articles in English with a minimum of 20 subjects. We also examined bibliographies of papers identified in this manner for additional sources. We found only 16 articles; most consisted of retrospective reports on treated samples. Overall, the available literature suggests that Tourette's disorder follows a remitting course in a sizeable number of individuals. Little has been published regarding predictors of remission or persistence. More work is needed using longitudinal prospective studies to better define the course and outcome of Tourette's disorder.
authors.affiliation: Joint Program in Pediatric Psychopharmacology, McLean Hospital, Belmont, MA 02478, USA.
authors.forename: B J
authors.initials: BJ
authors.lastname: Coffey
authors.forename: J
authors.initials: J
authors.lastname: Biederman
authors.forename: D A
authors.initials: DA
authors.lastname: Geller
authors.forename: T
authors.initials: T
authors.lastname: Spencer
authors.forename: K S
authors.initials: KS
authors.lastname: Park
authors.forename: S J
authors.initials: SJ
authors.lastname: Shapiro
authors.forename: S B
authors.initials: SB
authors.lastname: Garfield
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D002648:Child; D015897:Comorbidity; D018450:Disease Progression; D005060:Europe / Q000453:epidemiology; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D009656:North America / Q000453:epidemiology; D005879:Tourette Syndrome / Q000188:drug therapy* / Q000453:epidemiology* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D006220:Haloperidol