title: A child with adrenocortical adenoma accompanied by congenital hemihypertrophy: report of a case.
abstract: We report herein the findings of a 7-year-old male child with a ruptured adrenocortical adenoma and congenital hemihypertrophy which was incidentally detected after suffering a trauma. A review of 21 pediatric cases of adrenocortical neoplasms in the literature was made. The patient showed precocious puberty such as pubis and advanced bone age, but an endocrinological examination revealed no definite abnormalities. The right adrenal tumor with hematoma was resected after these evaluations. Adrenocortical adenoma is considered to occur more frequently in female children. However, the incidence of adrenocortical tumors accompanied by congenital hemihypertrophy does not differ between males and females. The outcomes were relatively good, although the observation periods were short in some patients. A large number of patients presented with a tumor and hemihypertrophy on the same side. This finding is of interest when considering the possible association between hemihypertrophy of the organs and tumor proliferation. However, their association in terms of development was unclear. It is necessary for patients with hemihypertrophy to have regular examinations for the possible development of malignant tumors, especially in the kidney, adrenal gland, and liver.
authors.affiliation: Department of Pediatric Surgery, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Hara
authors.forename: T
authors.initials: T
authors.lastname: Kishikawa
authors.forename: H
authors.initials: H
authors.lastname: Tomishige
authors.forename: O
authors.initials: O
authors.lastname: Nishikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Nishida
authors.forename: M
authors.initials: M
authors.lastname: Kongo
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000150:complications*; D018246:Adrenocortical Adenoma / Q000150:complications*; D002648:Child; D007839:Functional Laterality; D006801:Humans; D006984:Hypertrophy / Q000151:congenital; D008297:Male