title: Percutaneous transcatheter aortic disc valve prosthesis implantation: a feasibility study.
abstract: OBJECTIVE
  Over the past 30 years there have been experimental efforts at catheter-based management of aortic valve regurgitation with the idea of extending treatment to nonsurgical candidates. A new catheter-based aortic valve design is described.
  
  
  METHODS
  The new catheter-delivered valve consists of a stent-based valve cage with locking mechanism and a prosthetic flexible tilting valve disc. The valve cage is delivered first followed by deployment and locking of the disc. In acute experiments, valve implantation was done in four dogs.
  
  
  RESULTS
  Valve implantation was successful in all four animals. The implanted valve functioned well for the duration of the experiments (up to 3 hr).
  
  
  CONCLUSIONS
  The study showed the implantation feasibility and short-term function of the tested catheter-based aortic disc valve. Further experimental studies are warranted.
authors.affiliation: Department of Cardiology, Institute for Clinical and Experimental Medicine, Vídenská 1958/9, 140 21 Prague 4, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Sochman
authors.forename: J H
authors.initials: JH
authors.lastname: Peregrin
authors.forename: D
authors.initials: D
authors.lastname: Pavcnik
authors.forename: H
authors.initials: H
authors.lastname: Timmermans
authors.forename: J
authors.initials: J
authors.lastname: Rösch
mesh_terms: D000818:Animals; D001022:Aortic Valve Insufficiency / Q000628:therapy*; D004285:Dogs; D005240:Feasibility Studies; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D011474:Prosthesis Design; D015607:Stents