A mutation determining the loss of HLA-A2 antigen expression in a cervical carcinoma reveals novel splicing of human MHC class I classical transcripts in both tumoral and normal cells.
Serrano
A
A
Servicio de Análisis Clínicos Hospital Universitario, Virgen de las Nieves, Universidad de Granada, Spain.
Brady
C S
CS
Jimenez
P
P
Duggan-Keen
M F
MF
Mendez
R
R
Stern
P
P
Garrido
F
F
Ruiz-Cabello
F
F
D017398:Alternative Splicing; D001483:Base Sequence; D017931:DNA Primers / Q000235:genetics; D005091:Exons; D005260:Female; D015870:Gene Expression; D005805:Genes, MHC Class I; D015789:HLA-A2 Antigen / Q000235:genetics*; D006801:Humans; D009154:Mutation; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D012334:RNA, Neoplasm / Q000235:genetics / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D002583:Uterine Cervical Neoplasms / Q000235:genetics* / Q000276:immunology* / Q000378:metabolism
D017931:DNA Primers; D015789:HLA-A2 Antigen; D012333:RNA, Messenger; D012334:RNA, Neoplasm