title: Total synthesis of a demethoxy-egonol from Styrax obassia.
abstract: The total synthesis of a demethoxy-egonol isolated from Styrax obassia, 5-(3-hydroxypropyl)-2-(3',4'-methylenedioxyphenyl)benzofuran (9), is described. The key steps involve the construction of a 2-arylbenzofuran skeleton 7 from methyl 3-(4-hydroxyphenyl)propionate with 2-chloro-2-methylthio-(3',4'-methylenedioxy)acetophenone (6) in the presence of ZnCl2 and successive desulfurization of the resulting product 7.
authors.affiliation: Department of Chemistry, Dongeui University, Pusan, Korea. hdchoi@hyomin.dongeui.ac.kr
authors.forename: H D
authors.initials: HD
authors.lastname: Choi
authors.forename: M C
authors.initials: MC
authors.lastname: Ha
authors.forename: P J
authors.initials: PJ
authors.lastname: Seo
authors.forename: B W
authors.initials: BW
authors.lastname: Son
authors.forename: J C
authors.initials: JC
authors.lastname: Song
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis*; D010946:Plants, Medicinal
chemical_list: D001572:Benzofurans; C419663:demethoxy-egonol