title: [Phosphinic analog of methionine inhibits growth of leucosis cell L1210 and transforms to phosphinic analog of S-adenosylmethionine].
abstract: A phosphinic analogue of methionine bearing a phosphinic H(OH)(O)P fragment in place of the carboxyl group inhibited the growth of the L1210 cells and was intracellularly transformed to the phosphinic analogue of S-adenosylmethionine.
authors.forename: R M
authors.initials: RM
authors.lastname: Khomutov
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Zhukov
authors.forename: A R
authors.initials: AR
authors.lastname: Khomutov
authors.forename: E N
authors.initials: EN
authors.lastname: Khurs
authors.forename: D L
authors.initials: DL
authors.lastname: Kramer
authors.forename: J T
authors.initials: JT
authors.lastname: Miller
authors.forename: C W
authors.initials: CW
authors.lastname: Porter
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000378:metabolism / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D007939:Leukemia L1210 / Q000378:metabolism / Q000473:pathology; D008715:Methionine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology*; D010721:Phosphinic Acids / Q000378:metabolism / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
chemical_list: C415425:1-amino-3-(methyl-(5'-deoxy-5'-adenosyl)thio)propylphosphinic acid; C415423:1-amino-3-(methylthio)propylphosphinic acid; D000970:Antineoplastic Agents; D010721:Phosphinic Acids; D008715:Methionine