title: Infant zygosity can be assigned by parental report questionnaire data.
abstract: A parental report questionnaire posted to a population sample of 18-month-old twins correctly assigned zygosity in 95%of cases when validated against zygosity determined by identity of polymorphic DNA markers. The questionnaire was as accurate when readministered at 3 years of age, with 96% of children being assigned the same zygosity on both occasions. The results validate the use of parental report questionnaire data to determine zygosity in infancy.
authors.affiliation: Social Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, UK. t.price@iop.kcl.ac.uk
authors.forename: T S
authors.initials: TS
authors.lastname: Price
authors.forename: B
authors.initials: B
authors.lastname: Freeman
authors.forename: I
authors.initials: I
authors.lastname: Craig
authors.forename: S A
authors.initials: SA
authors.lastname: Petrill
authors.forename: L
authors.initials: L
authors.lastname: Ebersole
authors.forename: R
authors.initials: R
authors.lastname: Plomin
mesh_terms: D016009:Chi-Square Distribution; D002675:Child, Preschool; D004247:DNA / Q000235:genetics; D004739:England; D005260:Female; D005500:Follow-Up Studies; D005819:Genetic Markers / Q000235:genetics; D005838:Genotype; D006801:Humans; D007223:Infant; D008297:Male; D010290:Parents; D011110:Polymorphism, Genetic / Q000235:genetics; D011795:Surveys and Questionnaires; D014429:Twins, Dizygotic / Q000235:genetics; D014430:Twins, Monozygotic / Q000235:genetics; D014852:Wales
chemical_list: D005819:Genetic Markers; D004247:DNA