Decisionally impaired persons in research: refining the proposed refinements.
Amid the ethical debate about consent to research involving cognitively impaired subjects, author cautions against creating barriers to acceptable research and provides criteria by which guidelines should be developed.
DeRenzo
E G
EG
Department of Clinical Bioethics, National Institutes of Health, Bethesda, Maryland, USA.
D026724:Ethical Review; D028744:Ethics Committees, Research; D004992:Ethics, Medical; D035082:Federal Government; D033161:Government Regulation; D006805:Human Experimentation; D006801:Humans; D007258:Informed Consent; D016743:Mental Competency; D001523:Mental Disorders; D033242:Minors; D033281:Nontherapeutic Human Experimentation; D018579:Patient Selection; D035842:Research Subjects; D018570:Risk Assessment; D036302:Therapeutic Human Experimentation; D014481:United States