title: Histocompatibility antigen (HLA) associations with multiple sclerosis in Iran.
abstract: Human leukocyte antigen (HLA) types were obtained from 79 Iranian patients with multiple sclerosis and compared with 100 controls. The prevalence of HLA-A24 (30.3% versus 18.0%), HLA-DR2 (43.0% versus 28. 0%) and HLA-DR15 (36.7% versus 23.0%) were significantly increased in multiple sclerosis patients compared with controls. However age at onset, and disease status (relapsing - remitting or primary progressive) did not show an association with any particular HLA type. Multiple Sclerosis (2000) 6 317 - 319
authors.affiliation: Department of Neurology, Shohada Hospital, Tajrish, Tehran, Iran.
authors.forename: H
authors.initials: H
authors.lastname: Kalanie
authors.forename: M
authors.initials: M
authors.lastname: Kamgooyan
authors.forename: H
authors.initials: H
authors.lastname: Sadeghian
authors.forename: A R
authors.initials: AR
authors.lastname: Kalanie
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D001402:B-Lymphocytes / Q000276:immunology; D005260:Female; D020022:Genetic Predisposition to Disease; D015234:HLA-A Antigens / Q000032:analysis* / Q000276:immunology*; D059871:HLA-A24 Antigen; D006684:HLA-DR Antigens / Q000032:analysis* / Q000276:immunology*; D059810:HLA-DR Serological Subtypes; D015802:HLA-DR2 Antigen / Q000032:analysis / Q000276:immunology; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000453:epidemiology / Q000235:genetics / Q000276:immunology*
chemical_list: D015234:HLA-A Antigens; D059871:HLA-A24 Antigen; D006684:HLA-DR Antigens; D059810:HLA-DR Serological Subtypes; C106559:HLA-DR15 antigen; D015802:HLA-DR2 Antigen