Efficacy of inhalation form of furosemide to prevent postsurgical relapses of rhinosinusal polyposis.
The aim of the work is to demonstrate the efficacy of furosemide to prevent relapses of rhinosinusal polyps after surgical treatment. Two groups of people with rhinosinusal polyposis were enrolled: the study group consisted of 64 patients and the control group of 40 subjects. After surgical treatment, the study group started the therapy with topical furosemide; the control group had no treatment administered after the operation. Six years after the operation only 4 cases of relapse were noticed in the study group (10%), while there were 12 relapses, 4 slight (6.4%) and 8 severe (20%), in the control group. In conclusion, furosemide could represent a valid therapeutic aid in the prevention of nasosinusal polyps.
Passàli
D
D
ENT Department, University of Siena, Medical School, Siena, Italy.
Mezzedimi
C
C
Passàli
G C
GC
Bellussi
L
L
D000280:Administration, Inhalation; D000328:Adult; D005260:Female; D005665:Furosemide / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000517:prevention & control* / Q000601:surgery; D011182:Postoperative Care; D055502:Secondary Prevention; D016896:Treatment Outcome
D005665:Furosemide