title: Reversible leukoencephalopathy associated with re-infusion of DMSO preserved stem cells.
abstract: We report a case of posterior reversible leuko- encephalopathy (PRL) following the infusion of dimethylsulfoxide (DMSO) cryopreserved autologous stem cells in the setting of myeloablative chemotherapy in a patient with recurrent Ewing's sarcoma. Magnetic resonance (MR) imaging revealed white matter changes which resolved over the next 2 months. Bone Marrow Transplantation (2000) 26, 797-800.
authors.affiliation: Departments of Oncology and Pediatrics, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Higman
authors.forename: J D
authors.initials: JD
authors.lastname: Port
authors.forename: N J
authors.initials: NJ
authors.lastname: Beauchamp
authors.forename: A R
authors.initials: AR
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D015925:Cryopreservation / Q000379:methods; D004121:Dimethyl Sulfoxide / Q000633:toxicity*; D005260:Female; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D011859:Radiography; D012512:Sarcoma, Ewing / Q000628:therapy; D013234:Stem Cells; D014182:Transplantation, Autologous
chemical_list: D004121:Dimethyl Sulfoxide