title: [Angiosarcoma of the frontal sinus. Case report and review of the literature].
abstract: Angiosarcomas are very rare but highly malignant soft tissue tumors derived from the vascular endothelium. The tumor is most commonly found in the skin. The cancer is known to cause early and widespread metastases leading to a very poor prognosis of less than 24 months. The therapy of choice is radical surgery followed by adjuvant radiation. In this case study, we report on a patient with a very unusual localization of angiosarcoma in the frontal sinus. Based on this case, we discuss important aspects of tumor biology, diagnostic procedures, and histologic features as well as therapeutic options. We conclude that angiosarcoma has to be considered by a differential diagnosis in all head and neck neoplasias with uncertain histology.
authors.affiliation: Universitätsklinik für Hals-Nasen-Ohrenheilkunde Tübingen.
authors.forename: C
authors.initials: C
authors.lastname: Haferkamp
authors.forename: H
authors.initials: H
authors.lastname: Pressler
authors.forename: A
authors.initials: A
authors.lastname: Koitschev
mesh_terms: D000328:Adult; D005500:Follow-Up Studies; D005626:Frontal Sinus / Q000473:pathology / Q000601:surgery; D006394:Hemangiosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed