Spatial and temporal comparison of selected cancers in dogs and humans, Michigan, USA, 1964-1994.
Our aim was to investigate the geographic and time distributions of some biologically similar neoplasms in dogs and humans living in Michigan, USA, between 1964 and 1994. Our objective was to describe and compare the patterns of cancer in the two species while assessing the strength and dependence of those patterns. In this retrospective, registry-based study, histologically confirmed incident human and canine cancer cases were mapped, and second-order (K function) spatial analysis and one-dimensional nearest neighbor temporal analysis were performed on residence addresses and dates of hospital discharge/diagnosis. Included in the study were all 528 incident cases of canine lymphosarcoma, mammary adenocarcinoma, melanoma and spindle-cell sarcomas diagnosed at a veterinary teaching hospital between 1964 and 1994 having residence addresses in Ingham, Oakland, and Wayne Counties; and a stratified random sample of 913 incident human cases of comparable cancers diagnosed during the same time period from the same counties. Results suggest that processes determining spatial aggregation of cases in dogs and humans were not independent of each other, did not act uniformly over different geographic areas, operated at spatial scales <2000 m regardless of species, and tend to act upon dogs more strongly at shorter distances than on humans. Little evidence of interspecies concurrence of temporal clustering was found.
O'Brien
D J
DJ
Population Medicine Center, Michigan State University, East 48824, Lansing, MI 48824, USA. obriend@state.mi.us
Kaneene
J B
JB
Getis
A
A
Lloyd
J W
JW
Swanson
G M
GM
Leader
R W
RW
D000230:Adenocarcinoma / Q000453:epidemiology / Q000662:veterinary*; D000818:Animals; D001943:Breast Neoplasms / Q000453:epidemiology*; D004285:Dogs; D005843:Geography; D006801:Humans; D015994:Incidence; D008228:Lymphoma, Non-Hodgkin / Q000453:epidemiology / Q000662:veterinary*; D015674:Mammary Neoplasms, Animal / Q000453:epidemiology*; D008545:Melanoma / Q000453:epidemiology / Q000662:veterinary*; D008824:Michigan / Q000453:epidemiology; D010375:Pedigree; D011159:Population Surveillance; D012042:Registries; D012189:Retrospective Studies; D012509:Sarcoma / Q000453:epidemiology / Q000662:veterinary*; D012878:Skin Neoplasms / Q000453:epidemiology / Q000662:veterinary*