title: [Use of SPECT with (99m)Tc-Sestamibi in a patient affected by laryngeal carcinoma and parathyroid adenoma].
abstract: We report the case of a patient with a laryngeal carcinoma in whom asymptomatic hyperparathyroidism was also detected during the preoperative work-up. A planar (201)Thallium/(99m)Tc-pertecnetate subtraction scintigraphy was performed in order to locate the suspected parathyroid adenoma. The study showed a single area of increased (201)Thallium uptake just above the thyroid isthmus, likely due to the laryngeal tumor. The scintigraphic study was repeated using (99m)Tc-Sestamibi and (99m)Tc-pertechnetate and employing the SPECT technique. Both SPECT studies made it possible to identify correctly the parathyroid adenoma, located inferiorly and in a posterior position to the lower third of the right thyroid lobe. The laryngeal tumor and parathyroid adenoma could be excised in a single surgery session. This case is of interest due to the rarity of the coexistence of two neck tumors and the clear advantage shown by the SPECT technique with (99m)Tc-Sestamibi over the planar technique with 201Thallium.
authors.affiliation: Servicio de Medicina Nuclear, Università Cattolica del Sacro Cuore, Roma.
authors.forename: A
authors.initials: A
authors.lastname: Giordano
authors.forename: J
authors.initials: J
authors.lastname: Galli
authors.forename: L
authors.initials: L
authors.lastname: Corina
authors.forename: A M
authors.initials: AM
authors.lastname: Samanes Gajate
authors.forename: G
authors.initials: G
authors.lastname: D'Andrea
authors.forename: G
authors.initials: G
authors.lastname: Almadori
mesh_terms: D000236:Adenoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D006961:Hyperparathyroidism / Q000209:etiology; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D007825:Laryngectomy; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging*; D010282:Parathyroid Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D016105:Parathyroidectomy; D019275:Radiopharmaceuticals; D013670:Sodium Pertechnetate Tc 99m; D013382:Subtraction Technique; D017256:Technetium Tc 99m Sestamibi; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes; D017256:Technetium Tc 99m Sestamibi; D013670:Sodium Pertechnetate Tc 99m