Acute tubular necrosis induced by high level of cyclosporine A in a lung transplant.
We report a case of acute accidental cyclosporine A intoxication in a lung transplant patient. The intoxication led to renal failure due to acute tubular necrosis, which was partially reversible. A review of the literature on the renal consequences of cyclosporine A intoxication is given.
Dussol
B
B
Service de Néphrologie et Hémodialyse, Hôpital Sainte Marguerite, Marseille, France.
Reynaud-Gaubert
M
M
Saingra
Y
Y
Daniel
L
L
Berland
Y
Y
D000328:Adult; D016572:Cyclosporine / Q000008:administration & dosage / Q000506:poisoning*; D004305:Dose-Response Relationship, Drug; D062787:Drug Overdose / Q000209:etiology; D006801:Humans; D007683:Kidney Tubular Necrosis, Acute / Q000139:chemically induced*; D016040:Lung Transplantation; D008297:Male
D016572:Cyclosporine