Use of qualitative and quantitative fluorescence techniques to assess dermal exposure.
Fluorescent tracers provide a way of simultaneously assessing the mass of a contaminant hazardous substance on the surface of the skin of a worker and the area of skin exposed. These parameters, along with the duration of exposure and the estimated contaminant concentration in the skin contamination layer, can be used to calculate the likely uptake through the skin. Repeated assessment of the mass of tracer on a surface within a room or on the surface of the skin can also allow the net transfer of contaminant to that compartment to be estimated. Qualitative evaluation of transfer processes using fluorescent tracers can help identify important secondary sources of exposure.
Cherrie
J W
JW
University of Aberdeen and Institute of Occupational Medicine, 8 Roxburgh Place, Edinburgh, UK. john.cherrie@iomhq.org.uk
Brouwer
D H
DH
Roff
M
M
Vermeulen
R
R
Kromhout
H
H
D004784:Environmental Monitoring / Q000379:methods*; D005456:Fluorescent Dyes / Q000032:analysis*; D006801:Humans; D008954:Models, Biological; D016273:Occupational Exposure / Q000032:analysis*; D012107:Research Design; D018570:Risk Assessment / Q000379:methods*; D012869:Skin Absorption; D013997:Time Factors
D005456:Fluorescent Dyes