Gastrointestinal stromal tumors of the small intestine that expressed c-kit protein.
We report two patients with gastrointestinal stromal tumors (GISTs) of the small intestine that expressed c-kit protein (CD117). One was a 68-year-old woman with epigastralgia and vomiting. A submucosal tumor of the upper jejunum was detected, and partial resection was carried out. The histology revealed a GIST negative for CD34 but positive for CD117. The other was a 42-year-old woman with progressive anemia, melena and lower abdominal pain. Intussusception was detected, and a partial resection was carried out. A submucosal tumor of the lower jejunum was noted. The histology revealed a GIST positive for both CD34 and CD117.
Hoshino
N
N
Department of Internal Mecidine, JA Suzuka Hospital, Mie.
Murata
T
T
Oka
K
K
Kawakami
K
K
Hoshino
K
K
Sekoguchi
S
S
Suga
T
T
Nishimura
A
A
Kato
M
M
Hamada
M
M
D000328:Adult; D000368:Aged; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007580:Jejunal Neoplasms / Q000175:diagnosis / Q000235:genetics*; D008637:Mesenchymoma / Q000175:diagnosis / Q000235:genetics*; D019009:Proto-Oncogene Proteins c-kit / Q000096:biosynthesis*
D019009:Proto-Oncogene Proteins c-kit