Area under the curve and bioavailability.
The Area Under the Curve (AUC) is proportional to the fraction absorbed only if the clearance is constant and the concentration uniform; in all other cases the bioavailability cannot be determined by comparing AUCs.
Rescigno
A
A
rescigno@earthlink.net
D000818:Animals; D019540:Area Under Curve; D001682:Biological Availability; D006801:Humans