The histology and growth kinetics of canine renal oncocytoma.
A renal oncocytoma was diagnosed in a 10-year-old English springer spaniel with a 5-month history of anorexia, vomiting and weight loss. The tumour, which was localized to the kidney, was treated by simple nephrectomy and the dog made a full recovery. Histologically, the tumour consisted of cells with abundant eosinophilic cytoplasm forming acini and alveolar nests set within a loose fibrovascular stroma. The results of cell kinetic studies (AgNOR score 2.68, PCNA index 5.2%) were comparable with findings reported for benign human renal tumours. This appears to be the first reported case of renal oncocytoma in a dog.
Dempster
A G
AG
Southern Community Laboratories, Dunedin, New Zealand.
Delahunt
B
B
Malthus
A W
AW
Wakefield
J S
JS
D018249:Adenoma, Oxyphilic / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D002453:Cell Cycle; D004283:Dog Diseases / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D005260:Female; D007680:Kidney Neoplasms / Q000473:pathology / Q000662:veterinary*; D007700:Kinetics; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis
D018809:Proliferating Cell Nuclear Antigen