The relationship between peritoneal clearance and patient outcome in peritoneal dialysis patients.
Peritoneal clearance has not yet been proven to predict clinical outcome in peritoneal dialysis patients independent of residual renal function. Studies looking at the relationship between clearance and outcome have not been adequately powered to detect an effect. Pending better studies, clearance targets have been established, and higher clearances are being delivered. This article reviews existing literature on the topic and discusses the problems associated with carrying out a randomized controlled trial to address the issue.
Blake
P G
PG
Optimal Dialysis Research Unit, London Health Sciences Centre, Ontario, Canada.
D006801:Humans; D010530:Peritoneal Dialysis; D010537:Peritoneum / Q000378:metabolism*; D016896:Treatment Outcome