[Age-related changes of pulmonary surfactant in patients with acute peritonitis and their correction].
The results of research of the superficial activity of pulmonary surfactant (PS) in 124 patients with peritonitis are given. In patients younger than 60 years old PS changes depended on the phase: initial decrease in the reactive phase, stabilization--in the toxic phase, severe decrease--in the terminal one. In patients older than 60 progressive decrease of PS activity was shown, which was a risk factor for the bronchopulmonary complications: pneumonia, athelectasis, acute respiratory failure. The complex of actions for the prophylaxis and correction of PS insufficiency in patients with peritonitis is proposed. The efficacy of use of the exogenic PS substance sucrim was shown.
Shvets
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MA
D000208:Acute Disease; D000367:Age Factors; D000368:Aged; D000375:Aging / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000627:therapeutic use; D010538:Peritonitis / Q000378:metabolism* / Q000628:therapy; D011663:Pulmonary Surfactants / Q000378:metabolism*
D011663:Pulmonary Surfactants; D010100:Oxygen