title: Spontaneous regression of a solitary cerebral metastases in renal carcinoma followed by meningioma development under medroxyprogesterone acetate therapy.
abstract: A case of regression of a probable cerebral metastasis of a hypernephroma after nephrectomy and hormone therapy is presented. The patient subsequently developed a meningioma after therapy with medroxyprogesterone acetate. A relationship between meningioma growth and sex hormones has been documented, but little is known about the effect of hormone therapies on tumour growth.
authors.affiliation: Department of Neurosurgery, Oldchurch Hospital, GB-Romford, Essex, UK.
authors.forename: A E
authors.initials: AE
authors.lastname: Hensiek
authors.forename: A J
authors.initials: AJ
authors.lastname: Kellerman
authors.forename: J T
authors.initials: JT
authors.lastname: Hill
mesh_terms: D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects; D001932:Brain Neoplasms / Q000556:secondary*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy / Q000556:secondary*; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy*; D008297:Male; D017258:Medroxyprogesterone Acetate / Q000009:adverse effects; D008579:Meningioma / Q000139:chemically induced*; D009365:Neoplasm Regression, Spontaneous; D016609:Neoplasms, Second Primary / Q000139:chemically induced*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D017258:Medroxyprogesterone Acetate