Ki-67 reactivity in primary fallopian tube cancers.
Forty-four cases of primary cancer of the fallopian tube (PFTC) were analyzed as to Ki-67 expression, grade, stage and the cancer histological type. Among patients with an average age of 57.5 years (range 38-70 years), 27 patients were FIGO I, 7 were FIGO II and 10 were FIGO III. Histological classification of PFTC revealed 18 cases of endometrioid type, 9 serous, 7 undifferentiated, 6 urothelial, 2 clear-cell and 2 of other type. Histological grading revealed 11 cases of G1, 16 of G2 and 17 of G3 tumors. The quantity of Ki-67 positive cells was counted on 300 cancer cells in random high-power fields (10 x 40) and recorded as the labeling index (LI, %). Positive staining for Ki-67 was shown in the nuclei in all cases. Ki-67 LI values ranged from 14.2 to 97.2% (median 36.1). Ki-67 LI values were graded as > or = 36.1% as high and <36.1% as low. We did not find any significant differences in Ki-67 LI values among tumors of various clinical stages, histological grades and histological types. The p value was statistically significant only for stage as a prognostic factor.
Rabczyńiski
J
J
Department of Pathological Anatomy, University Medical School, Wrocław, Poland. akochman@anpat.am.wroc.pl
Kochman
A
A
Kowalski
P
P
Ziółkowski
P
P
D000328:Adult; D000368:Aged; D005185:Fallopian Tube Neoplasms / Q000145:classification / Q000276:immunology* / Q000401:mortality; D005260:Female; D006801:Humans; D019394:Ki-67 Antigen / Q000302:isolation & purification*; D008875:Middle Aged; D011379:Prognosis
D019394:Ki-67 Antigen