title: [Enzymatic assisted hatching in the infertile couple after failed attempts of IVF ET].
abstract: The study was conducted on the patients who had attempted and failed previous IVF procedures. The aim of this study was to determinate effectiveness sequential culture of embryos to blastocyst and assisted hatching by zona pellucida digestation by pronase. In this group the pregnancy rate was 24.1% compared to control 17.8%. The implantation rate was higher in study group than control one. It suggests that the culture embryos to balstocyste stage and assisted hatching by digestation by pronase is safe and effective mode of treatment of infertile couple after failed attempts IVF ET.
authors.affiliation: Zakład Endokrynologii Ginekologicznej AM w Białymstoku.
authors.forename: J
authors.initials: J
authors.lastname: Domitrz
authors.forename: S
authors.initials: S
authors.lastname: Wołczyński
authors.forename: M
authors.initials: M
authors.lastname: Syrewicz
authors.forename: W
authors.initials: W
authors.lastname: Kuczyński
authors.forename: J
authors.initials: J
authors.lastname: Szamatowicz
authors.forename: D
authors.initials: D
authors.lastname: Grochowski
authors.forename: M
authors.initials: M
authors.lastname: Szamatowicz
mesh_terms: D000328:Adult; D004624:Embryo Transfer / Q000379:methods*; D004622:Embryo, Mammalian / Q000187:drug effects / Q000502:physiology*; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011402:Pronase / Q000494:pharmacology*
chemical_list: D011402:Pronase