title: [Infective endocarditis: the course].
abstract: OBJECTIVE
  Epidemiological analysis of mortality due to infectious endocarditis (IE) and the disease evolution.
  
  
  METHODS
  A retrospective analysis was made of 109 IE lethal outcomes for 1987-1996 basing on the results of autopsies performed in Kemerovo prosectorium.
  
  
  RESULTS
  A significant trend to a rise in death rate of IE was registered. Among the deceased there is a higher proportion of old IE patients and patients with primary IE. Many of the patients died of staphylococcal IE, greater number of patients died of gram-negative infection and IE caused by injections of narcotic drugs.
  
  
  CONCLUSIONS
  Long-term trends in IE evolution are described.
authors.forename: E B
authors.initials: EB
authors.lastname: Brusina
authors.forename: A V
authors.initials: AV
authors.lastname: Kolomytsev
authors.forename: O L
authors.initials: OL
authors.lastname: Barbarash
authors.forename: N P
authors.initials: NP
authors.lastname: Burmatov
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001344:Autopsy; D001431:Bacteriological Techniques; D002648:Child; D002675:Child, Preschool; D004697:Endocarditis, Bacterial / Q000382:microbiology / Q000401:mortality*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009026:Mortality; D012189:Retrospective Studies; D012737:Sex Factors; D013203:Staphylococcal Infections / Q000382:microbiology / Q000401:mortality*; D013290:Streptococcal Infections / Q000382:microbiology / Q000401:mortality*