Pergolide-induced dyspnea, bilateral pleural effusion and peripheral edema.
A patient with severe Parkinson's disease presented with increasing dyspnea, bilateral pleural effusion and peripheral edema that were refractory to diuretic therapy and were first misdiagnosed as signs of right-sided heart failure. Pergolide was the only culprit for this devastating condition and on its discontinuation all signs of fluid retention resolved. In this report, drug reactions to ergots and dopamine agonists are discussed.
Varsano
S
S
Department of Pulmonary Medicine, Sapir Medical Center, Meir General Hospital, Kfar Sava and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. varsanos@bezeqint.net
Gershman
M
M
Hamaoui
E
E
D000368:Aged; D018491:Dopamine Agonists / Q000009:adverse effects*; D004417:Dyspnea / Q000139:chemically induced*; D015150:Echocardiography, Doppler; D004487:Edema / Q000139:chemically induced*; D006801:Humans; D008297:Male; D010300:Parkinson Disease / Q000188:drug therapy; D010479:Pergolide / Q000009:adverse effects*; D010996:Pleural Effusion / Q000139:chemically induced* / Q000175:diagnosis
D018491:Dopamine Agonists; D010479:Pergolide