Combinatorial methods to engineer small molecules for functional genomics.
Ellman
J A
JA
Department of Chemistry, University of California, Berkely 94720-1460, USA.
D000818:Animals; D016282:Aspartic Acid Endopeptidases / Q000037:antagonists & inhibitors; D002402:Cathepsin D / Q000037:antagonists & inhibitors; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D015853:Cysteine Proteinase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry; D010450:Endopeptidases / Q000378:metabolism; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry; D015894:Genome, Human; D023281:Genomics; D006801:Humans; D019151:Peptide Library; D010963:Plasmodium falciparum / Q000187:drug effects / Q000201:enzymology; D011480:Protease Inhibitors / Q000138:chemical synthesis / Q000737:chemistry; D013379:Substrate Specificity
D015853:Cysteine Proteinase Inhibitors; D005456:Fluorescent Dyes; D019151:Peptide Library; D011480:Protease Inhibitors; D010450:Endopeptidases; D016282:Aspartic Acid Endopeptidases; D002402:Cathepsin D