[Atopic dermatitis and domestic animals].
Several arguments are raised attributing to aeroallergens an important role in atopic dermatitis. The aeroallergens that penetrate the epidermis could be fixed by IgE on the Langerhans cells and then induce a cellular mediator reaction comparable to that of allergic contact eczema. Patch tests have been developed to evaluate the role of aeroallergens (dust mites, animal dander, etc.). Preventive anti-dust mites measures in the home of atopic patients are recommended. Eviction of domestic animals (cat, dog, etc.) or avoidance measures for animal dander in the home can produce improvement in atopic dermatitis. Oral specific immunotherapy is being validated as a treatment for this disease.
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Service de Dermatologie, C.H.U. Saint-Pierre, U.L.B.
D000485:Allergens / Q000009:adverse effects; D000818:Animals; D000829:Animals, Domestic; D002415:Cats; D003876:Dermatitis, Atopic / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D004285:Dogs; D004391:Dust / Q000009:adverse effects / Q000517:prevention & control; D007073:Immunoglobulin E / Q000276:immunology; D007167:Immunotherapy / Q000379:methods; D007801:Langerhans Cells / Q000276:immunology; D008925:Mites; D010328:Patch Tests; D010571:Pest Control / Q000379:methods; D011322:Primary Prevention / Q000379:methods
D000485:Allergens; D004391:Dust; D007073:Immunoglobulin E