[The role of the association of Opisthorchis felineus maritae with the Epstein-Barr virus in the cytogenetic sequelae of an opisthorchiasis infection].
The immunofluorescence analysis of Epstein-Barr virus (EBV) antigens in the body of Opisthorchis felineus (OF) helminths was carried out. It was found that EBV antigens located in eggs of helminth. Adding of OF antigens and/or EBV to the lymphocyte human cultures of healthy donors can induce a cytogenetic damage in cells. A role of EBV location in opisthorchis eggs in chromosome damage and cancer development is discussed.
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D000818:Animals; D000947:Antigens, Helminth / Q000032:analysis / Q000276:immunology; D000956:Antigens, Viral / Q000032:analysis / Q000276:immunology; D002478:Cells, Cultured; D002869:Chromosome Aberrations / Q000235:genetics*; D005455:Fluorescent Antibody Technique; D004854:Herpesvirus 4, Human / Q000276:immunology / Q000472:pathogenicity*; D006801:Humans; D009889:Opisthorchiasis / Q000235:genetics* / Q000276:immunology / Q000469:parasitology / Q000821:virology; D009891:Opisthorchis / Q000276:immunology / Q000472:pathogenicity* / Q000821:virology; D010063:Ovum / Q000276:immunology; D018709:Statistics, Nonparametric; D013601:T-Lymphocytes / Q000276:immunology / Q000469:parasitology / Q000648:ultrastructure / Q000821:virology
D000947:Antigens, Helminth; D000956:Antigens, Viral