Unexpected renal responses in space.
Urine output in astronauts following ingestion of an oral water load was low in space on the Russian space station Mir and less than during simulation by 6 degrees head-down bed rest. This surprising observation shows that the effects of gravity and weightlessness on fluid volume regulation are not well understood and that the head-down bed-rest model does not simulate the effects of weightlessness on renal water handling.
Norsk
P
P
Christensen
N J
NJ
Bie
P
P
Gabrielsen
A
A
Heer
M
M
Drummer
C
C
D000328:Adult; D000337:Aerospace Medicine; D000704:Analysis of Variance; D018475:Head-Down Tilt; D006801:Humans; D008297:Male; D014554:Urination / Q000502:physiology*; D014556:Urine; D014893:Weightlessness