title: Effectiveness of rotational atherectomy of right coronary artery ostial stenosis.
abstract: Balloon angioplasty and stenting of right coronary ostial stenosis may frequently be impeded by lesion calcification, whereas rotational atherectomy, which ablates calcified plaque, should treat these lesions effectively. Accordingly, we evaluated procedural success and longterm clinical outcome of rotational atherectomy of right coronary ostial stenosis. Procedural data were obtained from a comprehensive interventional registry and follow-up information was obtained by chart review and patient enquiry. All patients who developed recurrent angina underwent angiographic restudy. During a 5-year interval, 119 patients underwent rotational atherectomy of right coronary ostial stenosis. Multilesion interventions were performed in 55% of patients. Ostial lesions were 3.73+/-3.69 mm in length (mean +/- SD), and 57.1% were significantly calcified. Reference vessel diameter was 3.42+/-0.56 mm. Maximum burr:artery ratio was 0.64+/-0.1 with adjunct balloon angioplasty in 89.1% and adjunct stenting in 9.2%. Procedural success (<50% residual stenosis without major complication) was 97.5%, with 1.7% uncomplicated failure and 0.8% Q-wave infarction. Maximum residual stenosis was 15+/-17%. During 6-month follow-up, available in 94% of patients, 82.7% remained angina-free, 10.9% developed recurrent angina due to right coronary ostial restenosis, and 6.4% developed recurrent angina due to another lesion. Two years after intervention, target lesion revascularization rate was 16%. Predictors of symptomatic angiographic restenosis were dissection >10 mm, final minimal luminal diameter <2.5 mm, lesion length >10 mm, restenotic lesion, and diabetes. We conclude that rotational atherectomy of right coronary ostial stenosis results in excellent acute procedural success and in low incidence of clinical recurrence, with a high proportion of patients remaining angina-free 2 years after intervention.
authors.affiliation: The Southwest Cardiothoracic Centre, Derriford Hospital, Plymouth, United Kingdom. joseph.motwani@phnt.swest.nhs.uk
authors.forename: J G
authors.initials: JG
authors.lastname: Motwani
authors.forename: R E
authors.initials: RE
authors.lastname: Raymond
authors.forename: I
authors.initials: I
authors.lastname: Franco
authors.forename: S G
authors.initials: SG
authors.lastname: Ellis
authors.forename: P L
authors.initials: PL
authors.lastname: Whitlow
mesh_terms: D000368:Aged; D017225:Atherectomy, Coronary; D003324:Coronary Artery Disease / Q000601:surgery*; D003327:Coronary Disease / Q000601:surgery*; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012008:Recurrence; D012042:Registries; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome