title: [Epidemiology of adult neuromuscular disorders].
abstract: The percentage and cause of neuromuscular (NM) diseases have been analysed during a 15-year period of time. A NM disorder was found in 10,852 patients (or 14.4% of all neurological patients seen in our hospital). Mononeuropathies have been the most common causes, followed by polyneuropathies and radiculopathies, but with a variable percentage during time for the most frequent causes, that were carpal tunnel syndrome and diabetic polyneuropathies. Myopathies, diseases of the neuromuscular junction and anterior horn cell disorders counted for 5% among all NM disorders during the first 10 years (1% of all neurological patients) and for 12% during the last 5 years (2.4% of all neurological patients), this period corresponds to the opening of our outpatient clinic dedicated to NM diseases. Among polyneuropathies, the most common causes were diabetes mellitus, chronic inflammatory demyelinating polyneuropathies and the inherited forms of peripheral neuropathies. Among myopathies, the most frequently reported symptom was exercise-induced myalgia. The 2 most common muscular dystrophies (MD) were Steinert myotonic MD, and facio-scapulo-humeral MD. Other myopathies were rare, but of diverse causes, all of them corresponding to the newly introduced definition of Rare or Orphan Diseases.
authors.affiliation: Service de neurologie, Centre Hospitalier Universitaire Vaudois, Lausanne. thierry.kuntzer@chuv.hospvd.ch
authors.forename: T
authors.initials: T
authors.lastname: Kuntzer
authors.forename: R
authors.initials: R
authors.lastname: Lettry-Trouillat
authors.forename: J
authors.initials: J
authors.lastname: Bogousslavsky
mesh_terms: D000328:Adult; D006801:Humans; D009468:Neuromuscular Diseases / Q000453:epidemiology*; D010523:Peripheral Nervous System Diseases / Q000453:epidemiology*; D013557:Switzerland / Q000453:epidemiology