Acarbose and lymphocytic colitis.
We report a case of lymphocytic colitis induced by acarbose. Our immunopathological findings shown before and after rechallenge are consistent with a colonic immune-cell activation by the drug.
Piche
T
T
Raimondi
V
V
Schneider
S
S
Hébuterne
X
X
Rampal
P
P
D020909:Acarbose / Q000009:adverse effects*; D003092:Colitis / Q000139:chemically induced* / Q000473:pathology; D003106:Colon / Q000737:chemistry / Q000473:pathology; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects*; D007150:Immunohistochemistry; D008214:Lymphocytes / Q000187:drug effects* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000032:analysis
D006684:HLA-DR Antigens; D007004:Hypoglycemic Agents; D015375:Receptors, Interleukin-2; D020909:Acarbose