title: Inverted papilloma as a cause of high-grade ureteral obstruction.
abstract: Inverted papilloma of the urinary tract is a rare benign lesion. We report, to our knowledge, the first case of high-grade ureteral obstruction caused by an inverted papilloma with coexistent carcinomatous elements. Our patient was referred for evaluation of painless, gross hematuria. Imaging studies demonstrated a left proximal ureteral filling defect causing severe left-sided hydroureteronephrosis. Ureteroscopy demonstrated a 1-cm papillary lesion on the medial aspect of the proximal ureteral wall. Pathologic examination documented a lesion with elements of inverted papilloma and a small focus of well-differentiated transitional cell carcinoma. We discuss the management and significance of this rare urothelial lesion.
authors.affiliation: Division of Urology, University of California, San Diego, Medical Center, San Diego, California, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Cosgrove
authors.forename: M
authors.initials: M
authors.lastname: Monga
mesh_terms: D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis / Q000601:surgery; D006417:Hematuria / Q000209:etiology; D006801:Humans; D006869:Hydronephrosis / Q000209:etiology; D008297:Male; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000601:surgery; D018308:Papilloma, Inverted / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D014517:Ureteral Obstruction / Q000209:etiology*; D018666:Ureteroscopy; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery