title: [Anti-inflammatory, antibacterial and antimycotic effects of dark sulfonated shale oil (ichthammol)].
abstract: Dark sulfonated shale oil (Ichthammol, ammoniumbituminosulfonate) is an active ingredient of natural origin that was included in Annex II of European Council Regulation (EEC) 2377/90. Therefore, this well-tolerated substance is available further on as a dermatological agent for the application to animals from which food is produced for human consumption. The manifold pharmacological actions could be substantiated in numerous in-vitro studies using the Ichthammol from Seefeld, Austria. The antiinflammatory action which is well-known from clinical experience could be traced back to an influence of the substance on the formation, secretion and effect of inflammation mediators. Antibacterial and antimycotic actions which are well-known from clinical use could be confirmed in in-vitro studies as well.
authors.affiliation: Ichthyol-Gesellschaft, Hamburg.
authors.forename: G
authors.initials: G
authors.lastname: Gayko
authors.forename: W
authors.initials: W
authors.lastname: Cholcha
authors.forename: M
authors.initials: M
authors.lastname: Kietzmann
mesh_terms: D000818:Animals; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use; D006801:Humans; D009181:Mycoses / Q000188:drug therapy / Q000662:veterinary; D000644:Quaternary Ammonium Compounds / Q000627:therapeutic use*
chemical_list: D000891:Anti-Infective Agents, Local; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000935:Antifungal Agents; D003879:Dermatologic Agents; D000644:Quaternary Ammonium Compounds; C089399:ichthammol