title: Studying DNA topoisomerase I-targeted drugs in the yeast. Saccharomyces cerevisiae.
authors.affiliation: Department of Pharmaceutical Science, St. Jude Children's Research Hospital, Memphis, TN, USA.
authors.forename: M H
authors.initials: MH
authors.lastname: Woo
authors.forename: J R
authors.initials: JR
authors.lastname: Vance
authors.forename: M A
authors.initials: MA
authors.lastname: Bjornsti
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D002166:Camptothecin / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D002463:Cell Membrane Permeability; D002470:Cell Survival / Q000187:drug effects; D004264:DNA Topoisomerases, Type I / Q000235:genetics / Q000378:metabolism; D017353:Gene Deletion; D005800:Genes, Fungal; D005838:Genotype; D006801:Humans; D010957:Plasmids / Q000235:genetics; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D059004:Topoisomerase I Inhibitors; D014170:Transformation, Genetic
chemical_list: D000970:Antineoplastic Agents; D011994:Recombinant Proteins; D059004:Topoisomerase I Inhibitors; D004264:DNA Topoisomerases, Type I; D002166:Camptothecin