title: [A case of locally advanced rectal carcinoma with liver metastasis treated with a combination of CRT, HAI, and systemic chemotherapy].
abstract: A 55-year-old man with locally advanced rectal carcinoma and liver metastasis was treated with a combination of chemo-radiotherapy (5-FU suppository 100 mg/day and 63 Gy of RT), hepatic arterial infusion chemotherapy (5-FU 1,000 mg/3 h, biweekly), and systemic chemotherapy (5'-DFUR 800 mg/day + cimetidine 800 mg/day). His rectal tumor was reduced and his symptoms such as pain and bleeding had markedly decreased. The river metastasis did not change during the entire course. HAI and administration of 5-FU suppository, 5'-DFUR, and cimetidine were continued. As of 18 months after the onset of the combination therapy, NC has been maintained, and the general condition of the patient is favorable.
authors.affiliation: Dept. of Surgery, Suita Municipal Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Katsumoto
authors.forename: J
authors.initials: J
authors.lastname: Furukawa
authors.forename: S
authors.initials: S
authors.lastname: Yoshioka
authors.forename: T
authors.initials: T
authors.lastname: Shingai
authors.forename: K
authors.initials: K
authors.lastname: Takekuni
authors.forename: M
authors.initials: M
authors.lastname: Yukawa
authors.forename: K
authors.initials: K
authors.lastname: Nakaguchi
authors.forename: S
authors.initials: S
authors.lastname: Okajima
authors.forename: F
authors.initials: F
authors.lastname: Sue
authors.forename: T
authors.initials: T
authors.lastname: Hashimoto
authors.forename: S
authors.initials: S
authors.lastname: Teshima
mesh_terms: D000284:Administration, Oral; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D002927:Cimetidine / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005467:Floxuridine / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D011879:Radiotherapy Dosage; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D013488:Suppositories
chemical_list: D013488:Suppositories; D005467:Floxuridine; D002927:Cimetidine; D005472:Fluorouracil; C025034:doxifluridine