Modification of the aza-robinson annulation for the synthesis of 4-methyl-benzo[c]quinolizin-3-ones, potent inhibitors of steroid 5alpha-reductase 1.
Guarna
A
A
Dipartimento di Chimica Organica "U. Schiff" and Centro di Studio sulla Chimica e la Struttura dei Composti Eterociclici e loro Applicazioni, C.N.R., Università di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy. guarna@chimorg.unifi.it
Lombardi
E
E
Machetti
F
F
Occhiato
E G
EG
Scarpi
D
D
D058891:5-alpha Reductase Inhibitors; D004791:Enzyme Inhibitors / Q000138:chemical synthesis*; D011807:Quinolizines / Q000138:chemical synthesis*
C417556:4-methyl-benzo(c)quinolizin-3-one; D058891:5-alpha Reductase Inhibitors; D004791:Enzyme Inhibitors; D011807:Quinolizines