title: Anesthesia for kidney transplant surgery.
abstract: Organ viability associated with renal transplantation is a product of the managing of the donor patient, the allograft, and the recipient patient. Short- and long-term outcome is influenced by perioperative fluid and drug treatment, and the function and viability of the transplanted kidney seem to be optimized if graft perfusion is maximized through mild hypervolemia. At the same time, careful balancing of intraoperative fluids is necessary against cardiovascular problems frequently encountered in patients with uremia. Close intraoperative monitoring, optimization of intravascular fluid volume status to maximize kidney perfusion, and prompt correction of electrolyte disturbances (especially potassium) are key to short- and long-term success of renal transplants.
authors.affiliation: Department of Anesthesiology, Cleveland Clinic Foundation, Ohio, USA. sprungj@ccf.org
authors.forename: J
authors.initials: J
authors.lastname: Sprung
authors.forename: L
authors.initials: L
authors.lastname: Kapural
authors.forename: D L
authors.initials: DL
authors.lastname: Bourke
authors.forename: J F
authors.initials: JF
authors.lastname: O'Hara
mesh_terms: D000758:Anesthesia / Q000379:methods*; D006085:Graft Survival; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D007431:Intraoperative Complications; D016030:Kidney Transplantation; D011182:Postoperative Care; D011300:Preoperative Care
chemical_list: D007166:Immunosuppressive Agents