Junceellolides E-G, new briarane diterpenes from the West Pacific Ocean gorgonian Junceella fragilis.
Three new diterpenes, junceellolides E-G (1-3), along with an unnamed known diterpene 4, possessing the briarane carbon skeleton, have been isolated from the gorgonian Junceella fragilis collected in Taiwanese tropical waters. The structures of the new metabolites 1-3 were elucidated by extensive spectral analyses. The six-membered rings in junceellolides E and F (1 and 2) were found to exist in boat conformations. The structure, including the relative configuration of junceellolide E (1) was further confirmed by a single-crystal X-ray analysis.
Sung
P J
PJ
Department of Marine Resources and Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, Taiwan 804, Republic of China.
Wu
S L
SL
Fang
H J
HJ
Chiang
M Y
MY
Wu
J Y
JY
Fang
L S
LS
Sheu
J H
JH
D000818:Animals; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003063:Cnidaria / Q000737:chemistry*; D018360:Crystallography, X-Ray; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D005612:Freeze Drying; D009682:Magnetic Resonance Spectroscopy; D010140:Pacific Ocean; D016339:Spectrometry, Mass, Fast Atom Bombardment
D004224:Diterpenes; C418229:junceellolide E; C418230:junceellolide F; C418231:junceellolide G