title: Cytotoxic prenyleudesmane diterpenes from the fruits of Dysoxylum kuskusense.
abstract: Two new prenyleudesmane diterpenes, dysokusone D (1) and dysokusone E (2), were isolated from the fruits of Dysoxylum kuskusense and exhibited cytotoxicity against P-388, HT-29, and A549 cell lines. Their structures were determined by 1D and 2D NMR spectral analysis.
authors.affiliation: Department of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan.
authors.forename: C Y
authors.initials: CY
authors.lastname: Duh
authors.forename: S K
authors.initials: SK
authors.lastname: Wang
authors.forename: I S
authors.initials: IS
authors.lastname: Chen
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology; D004224:Diterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D005638:Fruit / Q000737:chemistry; D019073:HT29 Cells; D006801:Humans; D007941:Leukemia P388 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal / Q000737:chemistry*; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; C420036:dysokusone D; C420037:dysokusone E