title: Successful outcome of Scedosporium apiospermum disseminated infection treated with voriconazole in a patient receiving corticosteroid therapy.
abstract: A disseminated Scedosporium apiospermum infection was diagnosed in a woman with severe asthma and treated with corticosteroids. This fungi is resistant to fluconazole and amphotericin B. The infection was refractory to itraconazole, but responded successfully to voriconazole. A review of the literature is provided.
authors.affiliation: Department of Clinical Microbiology-Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain. pmunoz@micro.hggm.es
authors.forename: P
authors.initials: P
authors.lastname: Muñoz
authors.forename: M
authors.initials: M
authors.lastname: Marín
authors.forename: P
authors.initials: P
authors.lastname: Tornero
authors.forename: P
authors.initials: P
authors.lastname: Martín Rabadán
authors.forename: M
authors.initials: M
authors.lastname: Rodríguez-Creixéms
authors.forename: E
authors.initials: E
authors.lastname: Bouza
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use*; D001249:Asthma / Q000150:complications / Q000188:drug therapy; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D006801:Humans; D008172:Lung Diseases, Fungal / Q000188:drug therapy / Q000382:microbiology; D008271:Mycetoma / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D011743:Pyrimidines / Q000627:therapeutic use*; D021681:Scedosporium / Q000187:drug effects / Q000302:isolation & purification*; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use*; D065819:Voriconazole
chemical_list: D000305:Adrenal Cortex Hormones; D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole