title: [Adult acute lymphoblastic leukemia presenting a near haploid karyotype].
abstract: Thirty cases of childhood acute lymphoblastic leukemia (ALL) with a near haploid karyotype (< 30 chromosomes) have been reported so far. However, despite a few cases of severely hypodiploid (30-39 chromosomes) ALL, no near haploid cases have been reported in adult patients. Here, we describe a 64-year-old woman with ALL (L2, CD10+ 19+ 34+ HLA-DR+) presenting a near haploid karyotype of 27, X, +X, +6, +10, +21/54, idem x 2. She died of septic shock during complete remission 6.5 months after the diagnosis.
authors.affiliation: Department of Hematology, National Kyushu Cancer Center Hospital.
authors.forename: M
authors.initials: M
authors.lastname: Kimura
authors.forename: Y
authors.initials: Y
authors.lastname: Yufu
authors.forename: R
authors.initials: R
authors.lastname: Kawano
authors.forename: T
authors.initials: T
authors.lastname: Goto
authors.forename: H
authors.initials: H
authors.lastname: Takatsuki
authors.forename: N
authors.initials: N
authors.lastname: Uike
mesh_terms: D005260:Female; D006238:Haploidy; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics*