title: Optic neuropathy associated with laser in situ keratomileusis.
abstract: OBJECTIVE
  To report 4 cases of optic neuropathy following laser in situ keratomileusis (LASIK).
  
  
  METHODS
  Tertiary Care ophthalmic practices.
  
  
  METHODS
  In this retrospective observational case series, 4 patients who developed acute visual loss following LASIK are reported. All had clinical evidence of optic neuropathy. Two had optic disc edema and 2 had normal appearing optic discs initially. None of the patients experienced significant visual recovery, and all developed optic atrophy in the affected eye.
  
  
  RESULTS
  All patients had evaluations for alternative etiologies of their optic neuropathy, with negative results. All patients were therefore presumed to have experienced an ischemic optic neuropathy following LASIK.
  
  
  CONCLUSIONS
  Patients who have LASIK may experience an acute anterior or retrobulbar optic neuropathy. The etiology is unknown but may be related to the marked increase in intraocular pressure that occurs during a portion of the procedure.
authors.affiliation: Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
authors.forename: A G
authors.initials: AG
authors.lastname: Lee
authors.forename: T
authors.initials: T
authors.lastname: Kohnen
authors.forename: R
authors.initials: R
authors.lastname: Ebner
authors.forename: J L
authors.initials: JL
authors.lastname: Bennett
authors.forename: N R
authors.initials: NR
authors.lastname: Miller
authors.forename: T J
authors.initials: TJ
authors.lastname: Carlow
authors.forename: D D
authors.initials: DD
authors.lastname: Koch
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery; D009898:Optic Disk / Q000473:pathology; D018917:Optic Neuropathy, Ischemic / Q000209:etiology* / Q000473:pathology; D012189:Retrospective Studies; D014792:Visual Acuity