Morphology of testis and epididymis in an ethanol-drinking rat strain (UChA and UChB).
The objective of the present study was to analyze the prospective alterations of the testis and epididymis in a defined strain of alcoholic rats in order to contribute to our understanding of the effects of chronic alcoholism on reproduction. The testis and epididymis of the animals were submitted to morphological analysis by macroscopy, light microscopy and electron microscopy and to morphometric analysis. The UCh rats showed atrophy of the epithelium and reduction of testis and epididymis weight, liver hypertrophy and fat infiltration and alterations of the hypothalamus-pituitary axis. Ethanol induces changes in the weight and in the epithelium of the testis and epididymis and in the hypothalamus-pituitary axis of the UCh rats.
Martinez
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FE
Department of Anatomy, Institute of Biosciences, UNESP, Botucatu, SP, Brazil. martinez@ibb.unesp.br
Martinez
M
M
Padovani
C R
CR
Bustos-Obregón
E
E
D000437:Alcoholism / Q000473:pathology*; D000818:Animals; D002492:Central Nervous System Depressants / Q000633:toxicity*; D004822:Epididymis / Q000187:drug effects / Q000473:pathology* / Q000648:ultrastructure; D000431:Ethanol / Q000633:toxicity*; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D017208:Rats, Wistar; D013091:Spermatogenesis / Q000187:drug effects; D013737:Testis / Q000187:drug effects / Q000473:pathology* / Q000648:ultrastructure
D002492:Central Nervous System Depressants; D000431:Ethanol