title: "Hospital at home" versus hospital care in patients with exacerbations of chronic obstructive pulmonary disease: prospective randomised controlled trial.
abstract: OBJECTIVE
  To compare "hospital at home" and hospital care as an inpatient in acute exacerbations of chronic obstructive pulmonary disease.
  
  
  METHODS
  Prospective randomised controlled trial with three months' follow up.
  
  
  METHODS
  University teaching hospital offering secondary care service to 350 000 patients.
  
  
  METHODS
  Selected patients with an exacerbation of chronic obstructive pulmonary disease where hospital admission had been recommended after medical assessment.
  
  
  METHODS
  Nurse administered home care was provided as an alternative to inpatient admission.
  
  
  METHODS
  Readmission rates at two weeks and three months, changes in forced expiratory volume in one second (FEV(1)) from baseline at these times and mortality.
  
  
  RESULTS
  583 patients with chronic obstructive pulmonary disease referred for admission were assessed. 192 met the criteria for home care, and 42 refused to enter the trial. 100 were randomised to home care and 50 to hospital care. On admission, FEV(1) after use of a bronchodilator was 36.1% (95% confidence interval 2.4% to 69.8%) predicted in home care and 35.1% (6.3% to 63. 9%) predicted in hospital care. No significant difference was found in FEV(1 )after use of a bronchodilator at two weeks (42.6%, 3.4% to 81.8% versus 42.1%, 5.1% to 79.1%) or three months (41.5%, 8.2% to 74.8% versus 41.9%, 6.2% to 77.6%) between the groups. 37% of patients receiving home care and 34% receiving hospital care were readmitted at three months. No significant difference was found in mortality between the groups at three months (9% versus 8%).
  
  
  CONCLUSIONS
  Hospital at home care is a practical alternative to emergency admission in selected patients with exacerbations of chronic obstructive pulmonary disease.
authors.affiliation: Department of Medicine, University Hospital Aintree, Liverpool L9 7AL, UK.
authors.forename: L
authors.initials: L
authors.lastname: Davies
authors.forename: M
authors.initials: M
authors.lastname: Wilkinson
authors.forename: S
authors.initials: S
authors.lastname: Bonner
authors.forename: P M
authors.initials: PM
authors.lastname: Calverley
authors.forename: R M
authors.initials: RM
authors.lastname: Angus
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D005541:Forced Expiratory Volume / Q000502:physiology; D018575:Home Care Services, Hospital-Based / Q000458:organization & administration*; D006760:Hospitalization; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D011446:Prospective Studies; D011788:Quality of Life