[Juxtaglomerular cell tumor (reninoma) as the etiology of severe juvenile hypertension].
METHODS
A 20-year-old asymptomatic man was admitted with severe hypertension (250/150 mm Hg). Clinical examination was normal.


METHODS
Laboratory findings showed hypokalemia and secondary hyperaldosteronism. Abdominal ultrasound and CT-scan revealed an about 2.5 cm measuring tumor of the left kidney.


METHODS
Under antihypertensive treatment, a normal blood pressure profile could be achieved. With the diagnosis of a reninoma the patient was transferred to the urology department for tumor resection. In a 3-month follow-up the patient was normotensive without any medication.


CONCLUSIONS
Renin-secreting juxtaglomerular tumor of the kidney (reninoma) is a very rare but curable cause of severe hypertension. The syndrome of "primary hyperreninism" is characterized by severe hypertension, hypokalemia, secondary hyperaldosteronism and a renal mass in sonography.
Haag
M
M
Medizinische Klinik, Caritas-Krankenhauses Bad Mergentheim.
Selbach
J
J
Keberle
E
E
D000230:Adenocarcinoma / Q000175:diagnosis*; D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology*; D007680:Kidney Neoplasms / Q000175:diagnosis*; D008297:Male