Malignant transformation of ovarian endometriosis.
One hundred forty-seven cases of ovarian endometriosis, encountered from 1976 to 1999 at Tsukuba University Hospital, were studied to clarify the incidence of malignant transformation. There were 18 cases (12.2%) of atypical endometriosis, among which we found a case (5.6%) of ovarian cancer arising from endometriosis not diagnosed before surgery. This is accounted for 0.7% of all ovarian endometriosis cases. Because the incidence was equal to that of the previous reports, it is most likely that the malignant change in ovarian endometriosis occurred in 0.7% of this disease.
Nishida
M
M
Department of Obstetrics and Gynecology, Institute of Clinical Medicine, University of Tsukuba, Japan. mnishida@md.tsukuba.ac.jp
Watanabe
K
K
Sato
N
N
Ichikawa
Y
Y
D000328:Adult; D017677:Age Distribution; D000368:Aged; D001707:Biopsy, Needle; D018269:Carcinoma, Endometrioid / Q000453:epidemiology / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D015897:Comorbidity; D004715:Endometriosis / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010049:Ovarian Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D010051:Ovarian Neoplasms / Q000453:epidemiology* / Q000473:pathology*; D015995:Prevalence; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors