Early treatment of endometriosis with GnRH-agonists: impact on time to recurrence.
In a study, 52 patients with histologically confirmed endometriosis underwent a "three-step" therapy. The follow-up period was up to 60 months (median 33.5 months). If r-AFS-score was posttherapeutically 0, recurrence occurred latest after 36 months (median 18 months), if stage III was found posttherapeutically, recurrence occurred already latest after 18 months (median 8 months), (log-rank test P=0.0072). In our study we could confirm a clear relationship of recurrence of symptomatic endometriosis to the post-therapeutically achieved r-AFS-score.
Schindler
A E
AE
Department of Gynaecology of the University of Essen, Hufelandstrasse 55, D-45147 Essen, Germany.
Foertig
P
P
Kienle
E
E
Regidor
P A
PA
D004715:Endometriosis / Q000188:drug therapy*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives / Q000627:therapeutic use*; D006801:Humans; D012008:Recurrence; D013997:Time Factors
D007987:Gonadotropin-Releasing Hormone