title: Lichen scrofulosorum - a series of eight cases.
abstract: Lichen scrofulosorum is a rare entity of children and young adults. The cutaneous lesions are typically symptomless papular eruptions, associated with a strong Mantoux reaction, tuberculosis of lymph nodes and/or other organs. Eight patients between the ages of 5 and 36 years were included in this series. Lesions were commonly seen on the trunk, though a case of involvement of the palms and soles was also observed. Pulmonary tuberculosis was seen in 5 adults; 1 patient each had pleural effusion, tuberculous adenitis and tuberculoma, respectively. Histopathological examination typically showed epithelioid cell granulomas around hair follicles. The histogenesis is unclear, a type IV hypersensitivity reaction provoked by chronic tubercular infection is probable. The patients responded well to antituberculous therapy.
authors.affiliation: Institute of Pathology, Safdarjang Hospital, New Delhi, India.
authors.forename: K R
authors.initials: KR
authors.lastname: Beena
authors.forename: V
authors.initials: V
authors.lastname: Ramesh
authors.forename: A
authors.initials: A
authors.lastname: Mukherjee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D017512:Lichenoid Eruptions / Q000150:complications / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D014382:Tuberculosis, Cutaneous / Q000150:complications / Q000473:pathology*; D014397:Tuberculosis, Pulmonary / Q000150:complications