title: Detection of masses and clustered microcalcifications on data compressed mammograms: an observer performance study.
abstract: OBJECTIVE
  To evaluate observers' ability to detect breast masses and clustered microcalcifications depicted on data compressed mammograms, an observer performance study was performed.
  
  
  METHODS
  Eight observers assessed 60 mammographic images obtained in six modes, ranging from noncompressed to a maximum data compression level of 101:1. Observers were asked to rate the images on a scale of 0 to 100 for the likelihood of the presence of a mass and also independently for the likelihood of the presence of clustered microcalcifications. In addition, observers were asked to rate their subjective assessment of the quality of each image for the detection of a mass and separately for the detection of microcalcifications. Receiver operating characteristic analyses were performed.
  
  
  RESULTS
  The average area under the receiver operating characteristic curve, A(z), for the detection of clustered microcalcifications decreases significantly at the highest data compression level when compared with the noncompressed and two lowest levels of data compression (p < 0.01), and a trend test of the average area under the receiver operating characteristic curve for all observers is statistically significant (p < 0.05). No statistically significant differences among or between any of the data compression level modes for the detection of masses were detected.
  
  
  CONCLUSIONS
  At a high level of mammogram data compression, observer performance was degraded for the detection of clustered microcalcifications. Detection of masses was not affected by the data compression methods and levels used in this study.
authors.affiliation: All authors: Department of Radiology, University of Pittsburgh, A451 Scaife Hall, 3550 Terrace St., Pittsburgh, PA 15261-0001, USA.
authors.forename: W F
authors.initials: WF
authors.lastname: Good
authors.forename: J H
authors.initials: JH
authors.lastname: Sumkin
authors.forename: M
authors.initials: M
authors.lastname: Ganott
authors.forename: L
authors.initials: L
authors.lastname: Hardesty
authors.forename: B
authors.initials: B
authors.lastname: Holbert
authors.forename: C M
authors.initials: CM
authors.lastname: Johns
authors.forename: A H
authors.initials: AH
authors.lastname: Klym
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D002114:Calcinosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008327:Mammography / Q000379:methods*; D015588:Observer Variation; D012372:ROC Curve; D011856:Radiographic Image Enhancement