[Expression of the survivin gene in normal and hyperplastic endometrium].
OBJECTIVE
Surviving a novel anti-apoptotic gene is expressed during fetal development and in numerous human cancers.


METHODS
We analyzed the expression of surviving in human normal endometrium: proliferative n = 8, secretive n = 4 cases and hyperplastic endometrium 6 cases.


RESULTS
RT-PCR revealed surviving expression in all cases of normal and hyperplastic endometrium. The highest expression of surviving gene was observed in hyperplastic endometrium and in the late proliferative phase.
Tarkowski
R
R
Zakładu Genetyki Medycznej z Pracownia Cytodiagnostyki AM w Lublinie.
Wojcierowski
J
J
Polak
G
G
Kotarski
J
J
D017209:Apoptosis / Q000235:genetics*; D004717:Endometrium / Q000166:cytology* / Q000473:pathology; D005260:Female; D015870:Gene Expression / Q000235:genetics; D015972:Gene Expression Regulation, Neoplastic / Q000235:genetics*; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D008597:Menstrual Cycle / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction