title: Alveolar soft-part sarcoma of the cheek: report of a case with a review of the literature.
abstract: An alveolar soft-part sarcoma (ASPS) occurring in the cheek is described, with a review of the literature. The subject was a 25-year-old woman who presented with a large swelling in the left cheek. The lesion, initially diagnosed as a benign tumor on radiographic and computed tomographic examinations, was surgically excised. Histopathological examination of the mass revealed a nest-like or organoid cellular arrangement as confirmed by three-dimensional computer graphic reconstruction. The cytoplasm of the large polygonal tumor cells contained abundant diastase-resistant, PAS-positive inclusions, ultrastructurally confirmed to be crystalloid materials. The tumor cells were immunoreactive for anti-myoglobin, sarcomeric actin, and neuron-specific enolase antibodies, suggesting a myogenic origin.
authors.affiliation: Department of Oral Pathology, Tohoku University School of Dentistry, Sendai, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kimi
authors.forename: K
authors.initials: K
authors.lastname: Onodera
authors.forename: H
authors.initials: H
authors.lastname: Kumamoto
authors.forename: R
authors.initials: R
authors.lastname: Ichinohasama
authors.forename: S
authors.initials: S
authors.lastname: Echigo
authors.forename: K
authors.initials: K
authors.lastname: Ooya
mesh_terms: D000328:Adult; D002610:Cheek; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D018234:Sarcoma, Alveolar Soft Part / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery