Trends in antimicrobial-drug resistance in Japan.
Multidrug resistance in gram-positive bacteria has become common worldwide. In Japan until recently, gram-negative bacteria such as Pseudomonas aeruginosa, Klebsiella pneumoniae, and Serratia marcescens were controlled by carbapenems, fluoroquinolones, and aminoglycosides. However, several of these microorganisms have recently developed resistance against many antimicrobial drugs.
Arakawa
Y
Y
National Institute of Infectious Diseases, Tokyo, Japan. yarakawa@nih.go.jp
Ike
Y
Y
Nagasawa
M
M
Shibata
N
N
Doi
Y
Y
Shibayama
K
K
Yagi
T
T
Kurata
T
T
D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects; D006801:Humans; D007564:Japan; D016106:Methicillin Resistance; D010403:Penicillin Resistance; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects