title: Discorhabdin R: a new antibacterial pyrroloiminoquinone from two latrunculiid marine sponges, Latrunculia sp. and Negombata sp.
abstract: Two sponges belonging to the family Latrunculiidae (Negombata and Latrunculia sp.) collected during scientific trawling operations in Prydz Bay, Antarctica, and by scuba off Port Campbell, Victoria, have yielded a new antibacterial pyrroloiminoquinone, discorhabdin R (2). The structure was assigned as 2 on the basis of detailed spectroscopic analysis and comparison with the known co-metabolite discorhabdin B (3).
authors.affiliation: School of Chemistry, The University of Melbourne, Parkville, Victoria, 3010, Australia.
authors.forename: J
authors.initials: J
authors.lastname: Ford
authors.forename: R J
authors.initials: RJ
authors.lastname: Capon
mesh_terms: D000818:Animals; D000864:Antarctic Regions; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D011161:Porifera / Q000737:chemistry*; D015363:Quinolones / Q000737:chemistry* / Q000302:isolation & purification; D011809:Quinones / Q000737:chemistry* / Q000302:isolation & purification; D013141:Spiro Compounds; D013841:Thiazepines / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D000890:Anti-Infective Agents; D015363:Quinolones; D011809:Quinones; D013141:Spiro Compounds; D013841:Thiazepines; C573536:discorhabdin B; C419723:discorhabdin R