title: Association between nasal carriage of Staphylococcus aureus and infection in liver transplant recipients.
abstract: We reviewed the records of 87 patients who underwent liver transplantation and who were screened by use of nasal swabs on the day before surgery. Twenty-four patients harbored methicillin-susceptible Staphylococcus aureus (MSSA), and 8 harbored methicillin-resistant S. aureus (MRSA). MSSA infection occurred in 3 (12.5%) of 24 MSSA carriers and in 2 (3.2%) of 63 noncarriers (nonsignificant). In contrast, MRSA infection occurred more frequently in MRSA carriers (7 [87.5%] of 8) than in MRSA noncarriers (8 [10.1%] of 79; P<.001). Nasal carriage of MRSA is associated with a very high risk of MRSA infection in liver transplant recipients.
authors.affiliation: Hôpital Beaujon, Service de Microbiologie, Clichy, France.
authors.forename: F
authors.initials: F
authors.lastname: Bert
authors.forename: J O
authors.initials: JO
authors.lastname: Galdbart
authors.forename: V
authors.initials: V
authors.lastname: Zarrouk
authors.forename: J
authors.initials: J
authors.lastname: Le Mée
authors.forename: F
authors.initials: F
authors.lastname: Durand
authors.forename: F
authors.initials: F
authors.lastname: Mentré
authors.forename: J
authors.initials: J
authors.lastname: Belghiti
authors.forename: N
authors.initials: N
authors.lastname: Lambert-Zechovsky
authors.forename: B
authors.initials: B
authors.lastname: Fantin
mesh_terms: D000293:Adolescent; D000328:Adult; D015169:Colony Count, Microbial; D004269:DNA, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D008712:Methicillin / Q000494:pharmacology; D016106:Methicillin Resistance; D008875:Middle Aged; D009296:Nasal Cavity / Q000382:microbiology*; D011183:Postoperative Complications; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics
chemical_list: D004269:DNA, Bacterial; D008712:Methicillin