Autosomal recessive hereditary motor and sensory neuropathy.
Recent years have witnessed considerable advances in the nosography and molecular genetics of the hereditary motor and sensory neuropathies of autosomal dominant and X-linked recessive inheritance. Those with autosomal recessive inheritance are in general much less common, although in some communities where consanguineous marriages are prevalent they represent the most frequently encountered forms. They are now beginning to be characterized both clinically and genetically.
Thomas
P K
PK
University Department of Clinical Neurology, Institute of Neurology, London, UK. pkt.hotline@virgin.net
D001369:Axons; D002607:Charcot-Marie-Tooth Disease / Q000235:genetics; D003711:Demyelinating Diseases / Q000235:genetics; D005808:Genes, Recessive; D015417:Hereditary Sensory and Motor Neuropathy / Q000235:genetics; D006801:Humans; D009422:Nervous System Diseases / Q000235:genetics