Genotypic analysis of multidrug-resistant Salmonella enterica Serovar typhi, Kenya.
We report the emergence in Kenya during 1997-1999 of typhoid fever due to Salmonella enterica serovar Typhi resistant to ampicillin, tetracycline, chloramphenicol, streptomycin, and cotrimoxazole. Genotyping by pulsed-field gel electrophoresis of XbaI-digested chromosomal DNA yielded a single cluster. The multidrug-resistant S. Typhi were related to earlier drug- susceptible isolates but were unrelated to multidrug-resistant isolates from Asia.
Kariuki
S
S
Kenya Medical Research Institute, Nairobi, Kenya. skariuki@wtrl.or.ke
Gilks
C
C
Revathi
G
G
Hart
C A
CA
D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D005838:Genotype; D007630:Kenya; D019779:Salmonella enterica / Q000145:classification* / Q000187:drug effects / Q000235:genetics