title: The analgesic and anti-inflammatory effects of Portulaca oleracea L. subsp. Sativa (Haw.) Celak.
abstract: Many ethnic groups have used different species of Portulaca oleracea L., a member of the Family Portulacaceae, as vegetable and also herbal medicine against several diseases for many centuries. A review of the records in both folkloric and scientific literature indicates that Portulaca has many medicinal uses. After our previous preliminary screening of three species of the family for analgesic and anti-inflammatory properties, Portulaca oleracea L. subsp. sativa (Haw.) Celak. (a cultivar) was chosen for further work due to its abundant availability from reliable sources. The 10% ethanolic extract of the aerial parts (dried leaves and stem) showed significant anti-inflammatory and analgesic after intraperitoneal and topical but not oral administration when compared with the synthetic drug, diclofenac sodium as the active control. Results indicate this cultivar species of Portulaca also possesses some of the claimed traditional uses of the wild species in the relief of pain and inflammation.
authors.affiliation: Department of Biomedical Sciences, Zayed Complex for Herbal Research and Traditional Medicine, Ministry of Health, PO Box 29300, Abu Dhabi, United Arab Emirates. profkelvinchan@hotmail.com
authors.forename: K
authors.initials: K
authors.lastname: Chan
authors.forename: M W
authors.initials: MW
authors.lastname: Islam
authors.forename: M
authors.initials: M
authors.lastname: Kamil
authors.forename: R
authors.initials: R
authors.lastname: Radhakrishnan
authors.forename: M N
authors.initials: MN
authors.lastname: Zakaria
authors.forename: M
authors.initials: M
authors.lastname: Habibullah
authors.forename: A
authors.initials: A
authors.lastname: Attas
mesh_terms: D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D019684:Magnoliopsida / Q000737:chemistry*; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D010936:Plant Extracts