Microscopic polyarteritis with renal and cerebral involvement.
We report a 15-year-old girl who presented with renal failure requiring dialysis and a diagnosis of p-ANCA-associated vasculitis. She subsequently developed cerebral vasculitis during treatment with oral cyclophosphamide and prednisolone. Treatment with intravenous cyclophosphamide and plasma exchange produced a complete recovery.
Deshpande
P V
PV
Department of Nephrology, The Birmingham Children's Hospital, UK.
Gilbert
R
R
Alton
H
H
Milford
D V
DV
D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000293:Adolescent; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D001921:Brain / Q000473:pathology*; D003520:Cyclophosphamide / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D009778:Occipital Lobe / Q000473:pathology; D010530:Peritoneal Dialysis; D010951:Plasma Exchange; D010488:Polyarteritis Nodosa / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D011239:Prednisolone / Q000009:adverse effects / Q000627:therapeutic use; D014657:Vasculitis / Q000175:diagnosis* / Q000209:etiology; D020293:Vasculitis, Central Nervous System / Q000175:diagnosis* / Q000209:etiology
D019268:Antibodies, Antineutrophil Cytoplasmic; D003520:Cyclophosphamide; D011239:Prednisolone