title: Exercise rhabdomyolysis in military aircrew: two cases and a review of aeromedical disposition.
abstract: BACKGROUND
  Exercise rhabdomyolysis (ER) is a rare, sometimes catastrophic condition where muscle fibers breakdown in response to exertion and release their breakdown products into the circulation. While ER was brought to the medical community's attention largely through reports from military training establishments we are unaware of ER having resulted from the activities of military aircrew. This paper reports two cases of ER in military aircrew and discusses the condition and the approaches taken in determining their future aeromedical disposition.
  
  
  METHODS
  Rhabdomyolysis occurred in two military pilots as a result of their aircrew duties. One, an experienced pilot, suffered rhabdomyolysis as a result of centrifuge based G-training, while the other, a cadet in training, suffered rhabdomyolysis precipitated by exertion during moderately warm weather. Further investigation revealed the second case to also have the Malignant Hyperthermia Trait.
  After wide consultation and lengthy deliberations both of these aircrew were returned to their full previous flying status. No further complications or recurrences have occurred.
authors.affiliation: Institute of Aviation Medicine, RAAF Base Edinburgh, SA, Australia. dxw@ozemail.com.au
authors.forename: D B
authors.initials: DB
authors.lastname: Watson
authors.forename: G W
authors.initials: GW
authors.lastname: Gray
authors.forename: J J
authors.initials: JJ
authors.lastname: Doucet
mesh_terms: D000328:Adult; D000337:Aerospace Medicine; D001315:Australia; D002170:Canada; D002498:Centrifugation / Q000009:adverse effects; D004185:Disability Evaluation; D015444:Exercise; D006801:Humans; D007318:Inservice Training; D008297:Male; D008305:Malignant Hyperthermia / Q000175:diagnosis* / Q000209:etiology* / Q000517:prevention & control; D008889:Military Personnel; D010806:Physical Education and Training; D012206:Rhabdomyolysis / Q000097:blood / Q000175:diagnosis* / Q000201:enzymology / Q000209:etiology* / Q000517:prevention & control; D012307:Risk Factors