title: Controlled introduction of the sentinel node biopsy in breast cancer in a multi-centre setting: the role of a coordinator for quality control.
abstract: OBJECTIVE
  It is proposed that sentinel node biopsy should replace axillary lymph-node dissection. We analysed the role of a coordinator in the introduction of the sentinel node biopsy in breast cancer in a multi-centre setting to assure standardization and quality control.
  
  
  METHODS
  We included 232 operable breast cancer patients. Part of the procedure was an ultrasound examination of the axilla with fine needle aspiration cytology. The sentinel node was identified with 99m-Technetium and Patent Blue.
  
  
  RESULTS
  The results of the procedure, sensitivity and false negativity, were the same for the three participating hospitals. We think this is mostly due to the coordinator who supplied information about the technique, pitfalls and results to all teams.
  
  
  CONCLUSIONS
  Our experience regarding the organization aspects of introducing the sentinel node procedure in a multi-centre setting now serves as a model in organizing its application in a much wider number of hospitals.
authors.affiliation: Department of Surgery, University Hospital Rotterdam/Daniel den Hoed Cancer Center, The Netherlands.
authors.forename: A Y
authors.initials: AY
authors.lastname: de Kanter
authors.forename: A N
authors.initials: AN
authors.lastname: van Geel
authors.forename: M A
authors.initials: MA
authors.lastname: Paul
authors.forename: C H
authors.initials: CH
authors.lastname: van Eijck
authors.forename: S C
authors.initials: SC
authors.lastname: Henzen-Logmans
authors.forename: R H
authors.initials: RH
authors.lastname: Kruyt
authors.forename: E P
authors.initials: EP
authors.lastname: Krenning
authors.forename: A M
authors.initials: AM
authors.lastname: Eggermont
authors.forename: T
authors.initials: T
authors.lastname: Wiggers
mesh_terms: D001365:Axilla; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018567:Breast Neoplasms, Male / Q000473:pathology* / Q000601:surgery; D004396:Coloring Agents; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D015337:Multicenter Studies as Topic / Q000379:methods / Q000592:standards*; D011786:Quality Control; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012394:Rosaniline Dyes; D012680:Sensitivity and Specificity; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D013668:Technetium Tc 99m Aggregated Albumin; D014463:Ultrasonography
chemical_list: D004396:Coloring Agents; D019275:Radiopharmaceuticals; D012394:Rosaniline Dyes; D013668:Technetium Tc 99m Aggregated Albumin; C083602:technetium Tc 99m nanocolloid; C008769:sulfan blue