title: Smooth muscle tumor of the pleura. A case report and review of the literature.
abstract: Smooth muscle tumors of the serosal membranes are extremely rare and have received little attention in the literature. To the best of our knowledge, only 1 published series of 5 pleural smooth muscle neoplasms has been published to date. We describe a primary pleural neoplasm with smooth muscle differentiation documented by light microscopy, immunohistochemistry, and electron microscopy. This tumor originated in the parietal pleura in a 32-year-old white man and was diagnosed incidentally by chest radiography; the diagnosis was confirmed by magnetic resonance imaging and biopsy. Four years later, the tumor was noted to have increased in size and disseminated into the chest wall as a separate circumscribed mass located in the pectoral muscle. Both masses were resected and diagnosed as smooth muscle tumors. We conclude that smooth muscle tumor of the pleura is a well-defined entity with a low, but definite malignant potential; therefore, we recommend complete resection and long-term follow-up for all patients.
authors.affiliation: Department of Pathology, The Ohio State University Medical Center and Arthur G. James Cancer Hospital and Research Institute, Columbus 43210, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Proca
authors.forename: P
authors.initials: P
authors.lastname: Ross
authors.forename: J
authors.initials: J
authors.lastname: Pratt
authors.forename: W L
authors.initials: WL
authors.lastname: Frankel
mesh_terms: D000199:Actins / Q000032:analysis; D000328:Adult; D000368:Aged; D003893:Desmin / Q000032:analysis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000737:chemistry; D018995:Myosin Heavy Chains / Q000032:analysis; D010997:Pleural Neoplasms / Q000378:metabolism / Q000473:pathology*; D018235:Smooth Muscle Tumor / Q000378:metabolism / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D003893:Desmin; D014746:Vimentin; D018995:Myosin Heavy Chains