Giant cyclophanes built from polyphenyl aromatic substructures
Two very large cyclophanes (3, C(132)H(92)O(8)S(4); 4, C(172)H(120)O(8)S(4)) were prepared by means of short syntheses ( approximately 5 steps) from commercial starting materials. In each of these cyclophanes, two octaphenylnaphthalene subunits or two 1, 3-bis(pentaphenylphenyl)benzene subunits were tethered to form the final macrocycle. X-ray analysis of 3 shows it to have a collapsed conformation, but molecules of 4 have large central cavities which are aligned in the crystal to form wide, solvent-containing channels.
Pascal
RA
Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA.
Barnett
L
Qiao
X
Ho
DM