Anesthesia in a child with severe restrictive pulmonary dysfunction caused by chronic graft-versus-host disease.
Chronic graft-versus-host disease (GVHD) affects 30% to 50% of allogenic bone marrow transplant (BMT) recipients surviving the acute phase. We describe the clinical features and the anesthetic management of a child with a systemic form of GVHD resulting in severe restrictive pulmonary dysfunction.
Schure
A Y
AY
Department of Anesthesia, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Holzman
R S
RS
D000293:Adolescent; D000758:Anesthesia / Q000379:methods*; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002908:Chronic Disease; D005260:Female; D006086:Graft vs Host Disease / Q000150:complications*; D006801:Humans; D008171:Lung Diseases / Q000503:physiopathology*