title: Seroprevalence of antibodies to Chlamydia spp. in human immunodeficiency virus-infected subjects in Japan.
abstract: To evaluate the seropositivity of Chlamydia spp. in human immunodeficiency virus (HIV)-infected subjects in Japan, Chlamydia-specific antibodies in sera collected from 106 HIV-infected subjects were measured by the microimmunofluorescence test. The prevalence of C. pneumoniae-specific IgA, C. trachomatis-specific IgG and IgA and mean titers were significantly higher in the homosexual and heterosexual HIV-infected subjects than in the hemophilic patients and HIV-negative controls. These data indicate that the higher C. pneumoniae and C. trachomatis seroprevalence among HIV-infected subjects is probably due to an HIV risk factor, such as promiscuous sexual behavior, rather than to HIV infection itself.
authors.affiliation: Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan. nao@med.kawasaki-m.ac.jp
authors.forename: N
authors.initials: N
authors.lastname: Miyashita
authors.forename: Y
authors.initials: Y
authors.lastname: Niki
authors.forename: A
authors.initials: A
authors.lastname: Iwamoto
authors.forename: A
authors.initials: A
authors.lastname: Yasuoka
authors.forename: S
authors.initials: S
authors.lastname: Oka
authors.forename: K
authors.initials: K
authors.lastname: Kawata
authors.forename: A
authors.initials: A
authors.lastname: Ito
authors.forename: K
authors.initials: K
authors.lastname: Tomono
authors.forename: S
authors.initials: S
authors.lastname: Kohno
authors.forename: T
authors.initials: T
authors.lastname: Matsushima
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood*; D018791:CD4 Lymphocyte Count; D002689:Chlamydia / Q000276:immunology*; D005260:Female; D015658:HIV Infections / Q000382:microbiology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007564:Japan; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies
chemical_list: D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G