[Heterogeneity of ovarian epithelial tumors in analysis of nucleolar organizer regions (NORs) expression].
Nonhistone proteins associated with the nucleolar organizer regions (NORs) can be visualized by a silver-staining technique on paraffin-embedded tissues. The number of black dots (AgNORs) appearing on the nuclei are thought to reflect cell differentiation and can be used as a measurement of cellular proliferative activity. In this study we tested AgNOR staining in ovarian epithelial tumors to evaluate its diagnostic potential in distinguishing between borderline tumors and carcinomas.
Terlikowski
S
S
Zakładu Anatomii Patologicznej Akademii Medycznej w Białymstoku.
Lenczewski
A
A
Sulkowska
M
M
Famulski
W
W
Sulkowski
S
S
Musiatowicz
B
B
Kulikowski
M
M
D000328:Adult; D002277:Carcinoma / Q000378:metabolism / Q000473:pathology*; D002454:Cell Differentiation; D004848:Epithelium / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology*