title: [Photodynamic diagnosis and photodynamic therapy for experimental hepatoma with ME 2906].
abstract: We studied the effects of photodynamic diagnosis (PDD) and photodynamic therapy (PDT) in confirming the existence of hepatoma, using the new photosensitizer mono-L-aspartyl chlorine 6. Japanese white rabbits were selected for abdominal incision under intravenous anesthesia, and VX 2 tumor cells were transplanted into the left liver lobe to create a hepatoma model. In the experiment, hepatoma of 1 cm in diameter (at one week after transplantation) was radiated with a semiconducter laser (664 nm, 200 J/cm2) for treatment.
authors.affiliation: 3rd Dept. of Surgery, Toho University School of Medicine.
authors.forename: J
authors.initials: J
authors.lastname: Nakamura
authors.forename: Y
authors.initials: Y
authors.lastname: Sumiyama
authors.forename: H
authors.initials: H
authors.lastname: Kajiwara
authors.forename: M
authors.initials: M
authors.lastname: Nakamura
authors.forename: M
authors.initials: M
authors.lastname: Watanabe
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.forename: T
authors.initials: T
authors.lastname: Terada
authors.forename: J
authors.initials: J
authors.lastname: Nagao
authors.forename: S
authors.initials: S
authors.lastname: Kusachi
authors.forename: Y
authors.initials: Y
authors.lastname: Saida
authors.forename: S
authors.initials: S
authors.lastname: Usui
authors.forename: K
authors.initials: K
authors.lastname: Aizawa
mesh_terms: D000818:Animals; D002734:Chlorophyll / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D008114:Liver Neoplasms, Experimental / Q000175:diagnosis / Q000188:drug therapy*; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D011166:Porphyrins; D011817:Rabbits
chemical_list: C110704:PH-1126; D017319:Photosensitizing Agents; D011166:Porphyrins; D002734:Chlorophyll; C053434:Talaporfin