title: Antibacterial ent-kaurene from Brazilian propolis of native stingless bees.
abstract: Three ent-kaurene diterpenoids, not previously described as constituents of propolis, were isolated from a sample collected by Brazilian native bees Melipona quadrifasciata anthidioides. One of them, kaurenoic acid, as well as the total extract, displayed moderate antibacterial activity.
authors.affiliation: Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
authors.forename: M
authors.initials: M
authors.lastname: Velikova
authors.forename: V
authors.initials: V
authors.lastname: Bankova
authors.forename: I
authors.initials: I
authors.lastname: Tsvetkova
authors.forename: A
authors.initials: A
authors.lastname: Kujumgiev
authors.forename: M C
authors.initials: MC
authors.lastname: Marcucci
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D001516:Bees; D001938:Brazil; D004224:Diterpenes / Q000302:isolation & purification / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D011429:Propolis / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D004224:Diterpenes; C014341:argyrophilic acid; D011429:Propolis