title: Capillary electrophoresis-electrospray ion-trap mass spectrometry for the separation of chlorophenols.
abstract: Eighteen positional isomers of chlorophenols were separated by capillary electrophoresis (CE) and detected on-line by electrospray ionization ion-trap mass spectrometry (MS). Conditions for the coupling of CE to MS, e.g., the concentration of carrier electrolyte, the sheath liquid composition and the sheath gas flow-rate were optimized. Diethylmalonic acid (5 mM) at pH 7.25 and isopropanol-250 mM dimethylamine (80:20) as sheath liquid were used. The activation parameters for ion-trap mass spectrometric analysis of chlorophenols were optimized. The mass spectra, obtained for all the analytes, revealed that the [M-H]- ion was the base peak for all chlorophenols. Moreover, conditions for CE-MS-MS detection were established and [M-H-HCl]- ions were detected.
authors.affiliation: Departament de Química Analítica, Facultat de Química, Universitat de Barcelona, Spain.
authors.forename: O
authors.initials: O
authors.lastname: Jáuregui
authors.forename: E
authors.initials: E
authors.lastname: Moyano
authors.forename: M T
authors.initials: MT
authors.lastname: Galceran
mesh_terms: D002733:Chlorophenols / Q000302:isolation & purification*; D019075:Electrophoresis, Capillary / Q000379:methods*; D012680:Sensitivity and Specificity; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
chemical_list: D002733:Chlorophenols