Desymmetrization of meso-dialdehydes with optically active cyclopentadienyldialkoxyallyltitanium complexes
Optically active cyclopentadienyldialkoxyallyltitanium complexes have been employed for the desymmetrization of meso-dialdehydes. Allylation of these dialdehydes and subsequent oxidation afford chiral lactones with good diastereoselectivity and excellent enantioselectivity.
BouzBouz
S
Laboratoire de Chimie Organique associe au CNRS, ESPCI, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
Popkin
ME
Cossy
J