title: [Cancer of the ethmoid sinus].
abstract: Ethmoid sinuses are located at the level of the anterior skull base. Seventy to 80% of the ethmoid sinus malignant tumors are adenocarcinomas. Wood dust exposure is a carcinogen agent to ethmoid adenocarcinoma. More than 90% of patients with ethmoid adenocarcinoma are woodworkers. Craniofacial computed tomography scan and magnetic resonance imaging are always performed before treatment. It is always a multidisciplinary treatment including surgical resection followed by external radiation therapy. Some authors recommend a neoadjuvant chemotherapy. A total ethmoidectomy including the cribriform plate through a transcranial subfrontal approach is the best surgical technique. Local recurrence is the most frequent cause of failure; 5-year survival of patients with ethmoid adenocarcinoma is around 50%. A regular follow-up including clinical and radiological examination is always required.
authors.affiliation: Service d'oto-rhino-laryngologie et de chirurgie de la face et du cou Hôpital Laennec, Paris. daniel.brasnu@Lnc.ap-hop-paris.fr
authors.forename: D
authors.initials: D
authors.lastname: Brasnu
authors.forename: F X
authors.initials: FX
authors.lastname: Roux
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005005:Ethmoid Sinus; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008279:Magnetic Resonance Imaging; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D011182:Postoperative Care; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D013997:Time Factors
chemical_list: D002945:Cisplatin; D005472:Fluorouracil