title: Resistance of tumor cells to chemo- and radiotherapy modulated by the three-dimensional architecture of solid tumors and spheroids.
authors.affiliation: Medical Biophysics Department, British Colombia Cancer Research Centre, Vancouver, Canada.
authors.forename: R E
authors.initials: RE
authors.lastname: Durand
authors.forename: P L
authors.initials: PL
authors.lastname: Olive
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology; D001562:Benzimidazoles / Q000378:metabolism; D002450:Cell Communication; D002469:Cell Separation / Q000295:instrumentation / Q000379:methods; D048429:Cell Size; D002843:Chromatin / Q000378:metabolism; D004273:DNA, Neoplasm / Q000378:metabolism; D019008:Drug Resistance, Neoplasm; D005047:Etoposide / Q000494:pharmacology; D005434:Flow Cytometry / Q000295:instrumentation / Q000379:methods; D005456:Fluorescent Dyes / Q000378:metabolism; D015972:Gene Expression Regulation, Neoplastic; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D018874:Spheroids, Cellular / Q000166:cytology / Q000187:drug effects* / Q000528:radiation effects*; D014407:Tumor Cells, Cultured
chemical_list: D000970:Antineoplastic Agents; D001562:Benzimidazoles; D002843:Chromatin; D004273:DNA, Neoplasm; D005456:Fluorescent Dyes; D005047:Etoposide; C017807:bisbenzimide ethoxide trihydrochloride