Tuberculosis and HIV Infection.
We review important new recommendations on the treatment and prophylaxis of tuberculosis in HIV-infected individuals. Large-scale studies and expert consensus panels have both concluded that shorter courses and intermittent antituberculous regimens are adequate for the treatment of dually infected individuals. Also, the substitution of rifabutin for rifampin for the treatment and prophylaxis of tuberculosis has been shown to be advantageous, providing equivalent efficacy to regimens containing rifampin, and fewer drug interactions with antiretroviral medications.
Buitrago
MI
AIDS Program, Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, 135 College Street, Suite 323, New Haven, CT 06520, USA.
Friedland
G