[Ultrastructure of the thymus after gamma irradiation during inhibition of steroidogenesis].
Experimental investigations on rats have shown that development of dyshormonal immunodepression after ionizing radiation in sublethal doses depends on indirect effect of corticosteroids. Inhibition of steroidogenesis corrects ultrastructural lesions of the thymus after gamma irradiation.
Popuchiev
V V
VV
Medical Radiological Research Center, Obninsk.
Iakovleva
N D
ND
Kita
K
K
Kotlova
L N
LN
Kvetnoĭ
I M
IM
D000818:Animals; D005720:Gamma Rays; D005938:Glucocorticoids / Q000037:antagonists & inhibitors*; D008297:Male; D008797:Metyrapone / Q000494:pharmacology*; D008854:Microscopy, Electron; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000378:metabolism / Q000528:radiation effects* / Q000648:ultrastructure*
D005938:Glucocorticoids; D008797:Metyrapone