title: Rolandic encephalopathy and epilepsia partialis continua following bone marrow transplant.
abstract: Epilepsia partialis continua (EPC) is a condition defined by prolonged focal myoclonus. Often resistant to therapy, EPC in children is frequently present in Rasmussen encephalitis, a form of chronic encephalitis of uncertain etiology. We discuss a child who developed bilateral EPC 5 months after a bone marrow transplant. Neuroimaging studies showed signal abnormalities on both sensory-motor areas. An extensive search failed to reveal the etiology of the disorder, but treatment with a broad-spectrum anti-viral agent was associated with resolution of the process. An unidentified infectious agent may be responsible for an encephalitis of the motor strip in immunosuppressed patients.
authors.affiliation: Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
authors.forename: N L
authors.initials: NL
authors.lastname: Antunes
authors.forename: F
authors.initials: F
authors.lastname: Boulad
authors.forename: V
authors.initials: V
authors.lastname: Prasad
authors.forename: M
authors.initials: M
authors.lastname: Rosenblum
authors.forename: E
authors.initials: E
authors.lastname: Lis
authors.forename: M
authors.initials: M
authors.lastname: Souweidane
mesh_terms: D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002648:Child; D004660:Encephalitis / Q000209:etiology* / Q000628:therapy; D017036:Epilepsia Partialis Continua / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008297:Male