Biarylpropylsulfonamides as novel, potent potentiators of 2-amino-3- (5-methyl-3-hydroxyisoxazol-4-yl)- propanoic acid (AMPA) receptors.
Ornstein
P L
PL
NPS Allelix Corporation, 6850 Goreway Drive, Mississaugua, Ontario L4V 1V7, Canada. ornstein_paul@lilly.com
Zimmerman
D M
DM
Arnold
M B
MB
Bleisch
T J
TJ
Cantrell
B
B
Simon
R
R
Zarrinmayeh
H
H
Baker
S R
SR
Gates
M
M
Tizzano
J P
JP
Bleakman
D
D
Mandelzys
A
A
Jarvie
K R
KR
Ho
K
K
Deverill
M
M
Kamboj
R K
RK
D002460:Cell Line; D006801:Humans; D018091:Receptors, AMPA / Q000187:drug effects* / Q000378:metabolism; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D018091:Receptors, AMPA; D013449:Sulfonamides; C104724:glutamate receptor ionotropic, AMPA 4