title: Prophylactic therapy in a pregnant woman with severe factor VII deficiency.
abstract: This paper reports a case of factor VII deficiency, a very rare autosomal recessive disorder, in a primipara at 37 weeks of gestation in whom we administered prophylactic therapy with factor VII every 12 h until 24 h after delivery. The prophylactic use of factor VII enabled the woman to deliver without hemorrhagic complications.
authors.affiliation: Department of Obstetrics and Gynecology, University of Siena, Italy. deleo@unisi.it
authors.forename: V
authors.initials: V
authors.lastname: De Leo
authors.forename: A
authors.initials: A
authors.lastname: Ditto
authors.forename: G
authors.initials: G
authors.lastname: Morgante
authors.forename: A
authors.initials: A
authors.lastname: La Marca
authors.forename: C
authors.initials: C
authors.lastname: Massafra
authors.forename: C G
authors.initials: CG
authors.lastname: Guidoni
mesh_terms: D000328:Adult; D005167:Factor VII / Q000008:administration & dosage*; D005168:Factor VII Deficiency / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control; D011256:Pregnancy Outcome; D011263:Pregnancy Trimester, Third; D018566:Pregnancy, High-Risk; D012720:Severity of Illness Index
chemical_list: D005167:Factor VII