Association between nasal carriage of Staphylococcus aureus and infection in liver transplant recipients.
We reviewed the records of 87 patients who underwent liver transplantation and who were screened by use of nasal swabs on the day before surgery. Twenty-four patients harbored methicillin-susceptible Staphylococcus aureus (MSSA), and 8 harbored methicillin-resistant S. aureus (MRSA). MSSA infection occurred in 3 (12.5%) of 24 MSSA carriers and in 2 (3.2%) of 63 noncarriers (nonsignificant). In contrast, MRSA infection occurred more frequently in MRSA carriers (7 [87.5%] of 8) than in MRSA noncarriers (8 [10.1%] of 79; P<.001). Nasal carriage of MRSA is associated with a very high risk of MRSA infection in liver transplant recipients.
Bert
F
F
Hôpital Beaujon, Service de Microbiologie, Clichy, France.
Galdbart
J O
JO
Zarrouk
V
V
Le Mée
J
J
Durand
F
F
Mentré
F
F
Belghiti
J
J
Lambert-Zechovsky
N
N
Fantin
B
B
D000293:Adolescent; D000328:Adult; D015169:Colony Count, Microbial; D004269:DNA, Bacterial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D008712:Methicillin / Q000494:pharmacology; D016106:Methicillin Resistance; D008875:Middle Aged; D009296:Nasal Cavity / Q000382:microbiology*; D011183:Postoperative Complications; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics
D004269:DNA, Bacterial; D008712:Methicillin