title: Diheteropeptin, a novel substance with TGF-beta-like activity, produced by a fungus, Diheterospora chlamydosporia. II. Physico-chemical properties and structure elucidation.
abstract: The structure of diheteropeptin (1), a TGF-beta-like active substance from Diheterospora chlamydosporia Q58044, was determined to be a new cyclotetrapeptide, cyclo[2aminoisobutyryl-(S)-phenylalanyl-(R)-prolyl-(2S,8R,9R)-2-am ino-8,9-dihydroxydecanoyl-] by NMR, mass spectrometric and chemical studies.
authors.affiliation: Institute of Molecular and Cellular Biosciences, The University of Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Masuoka
authors.forename: K
authors.initials: K
authors.lastname: Shin-Ya
authors.forename: K
authors.initials: K
authors.lastname: Furihata
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: Y
authors.initials: Y
authors.lastname: Takebayashi
authors.forename: K
authors.initials: K
authors.lastname: Nagai
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: Y
authors.initials: Y
authors.lastname: Hayakawa
authors.forename: H
authors.initials: H
authors.lastname: Seto
mesh_terms: D002942:Circular Dichroism; D003652:Decanoic Acids / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D006999:Hypocreales / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013237:Stereoisomerism; D016212:Transforming Growth Factor beta / Q000494:pharmacology
chemical_list: D003652:Decanoic Acids; D016212:Transforming Growth Factor beta; C111146:diheteropeptin