[Hydatidiform mole with coexistent fetus. Cytogenetic features, diagnosis, and management].
Hydatidiform mole with coexistent fetus is an unusual entity caused by two distinct types of pregnancy: the first one is a partial hydatidiform mole, while the second is a twin pregnancy in which a mole coexists with a normal fetus. In these two separate genetic entities, the counseling and the mother-fetus prognosis are different. Two cases of mole with coexistent fetus are reported: a partial hydatidiform mole typically tripliod and a partial mole with unusual diploid karyotype. Prenatal diagnosis is remarkable for the evaluation of fetus development related with his karyotype. Triplody excludes all hope of a non-malformed surviving child and termination of pregnancy is desirable, while normal karyotype the possibility of a continuation of pregnancy may be considered.
Pollio
F
F
Istituto di Ginecologia Ostetricia, Facoltà di Medicina e Chirurgia, Università degli Studi, Napoli.
Daniele
F
F
Micalef
R
R
Citarella
F
F
Desantis
B
B
Ercolano
S
S
Scaramellino
M
M
Catalano
D
D
D000293:Adolescent; D000328:Adult; D005260:Female; D005333:Fetus; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000628:therapy