[Polymorphism of the dopamine D2 receptor gene in populations from the Volga-Ural region].
The PCR technique was used to analyze the TaqIA- and NcoI-polymorphisms at the dopamine D2 receptor gene (DRD2) in eight populations of the Volga-Ural region belonging to Turkic (Bashkirs, Tatars, and Chuvashes), Finno-Ugric (Maris, Komis, Mordovians, and Udmurts), and Eastern-Slavic (Russians) ethnic groups. Population-specific patterns of the main TaqIA- and NcoI-polymorphisms distribution were established. Specific trends in changes of genotype and allele frequency of the dopamine D2 receptor gene depending on the ethnicity of the population were revealed.
Galeeva
A R
AR
Institute of Biochemistry and Genetics, Russian Academy of Sciences, Ufa, Bashkortostan.
Iur'ev
E B
EB
Khusnutdinova
E K
EK
D005828:Genetics, Population; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D017448:Receptors, Dopamine D2 / Q000235:genetics*; D012426:Russia
D017448:Receptors, Dopamine D2