title: Unexpected renal responses in space.
abstract: Urine output in astronauts following ingestion of an oral water load was low in space on the Russian space station Mir and less than during simulation by 6 degrees head-down bed rest. This surprising observation shows that the effects of gravity and weightlessness on fluid volume regulation are not well understood and that the head-down bed-rest model does not simulate the effects of weightlessness on renal water handling.
authors.forename: P
authors.initials: P
authors.lastname: Norsk
authors.forename: N J
authors.initials: NJ
authors.lastname: Christensen
authors.forename: P
authors.initials: P
authors.lastname: Bie
authors.forename: A
authors.initials: A
authors.lastname: Gabrielsen
authors.forename: M
authors.initials: M
authors.lastname: Heer
authors.forename: C
authors.initials: C
authors.lastname: Drummer
mesh_terms: D000328:Adult; D000337:Aerospace Medicine; D000704:Analysis of Variance; D018475:Head-Down Tilt; D006801:Humans; D008297:Male; D014554:Urination / Q000502:physiology*; D014556:Urine; D014893:Weightlessness