title: Acute renal failure in a healthy young adult after dextran 40 infusion for external-ear reattachment surgery.
abstract: Dextran 40 is used to improve the microcirculation after certain surgical procedures. We report a rare case of acute anuric renal failure in a healthy young adult after administration of dextran 40 to improve the microcirculation following ear-reattachment surgery. The renal failure was subsequently reversed by plasmapheresis and intensive care support. Although rare in the young and fit, the risk of developing acute anuric renal failure exists with administration of dextran 40 and appropriate monitoring is essential.
authors.affiliation: Division of Otorhinolaryngology, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong.
authors.forename: R K
authors.initials: RK
authors.lastname: Tsang
authors.forename: J S
authors.initials: JS
authors.lastname: Mok
authors.forename: Y S
authors.initials: YS
authors.lastname: Poon
authors.forename: A
authors.initials: A
authors.lastname: van Hasselt
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000628:therapy; D000293:Adolescent; D003422:Critical Care; D003911:Dextrans / Q000009:adverse effects*; D004431:Ear, External / Q000601:surgery*; D006801:Humans; D008297:Male; D010952:Plasma Substitutes / Q000009:adverse effects*; D010956:Plasmapheresis; D012092:Replantation; D016896:Treatment Outcome
chemical_list: D003911:Dextrans; D010952:Plasma Substitutes