The Collaborative Longitudinal Personality Disorders Study: baseline Axis I/II and II/II diagnostic co-occurrence.
OBJECTIVE
To describe baseline diagnostic co-occurrence in the Collaborative Longitudinal Personality Disorders Study.


METHODS
Six hundred and sixty-eight patients were reliably assessed with diagnostic interviews for DSM-IV Axis I and II disorders to create five groups: Schizotypal (STPD), Borderline (BPD), Avoidant (AVPD), Obsessive-Compulsive (OCPD) and Major Depressive Disorder (MDD) without personality disorder (PD).


RESULTS
Mean number of Axis I lifetime diagnoses was 3.4; STPD and BPD groups had more diagnoses than AVPD, OCPD, and MDD groups. Significant Axis I co-occurrences emerged for Social Phobia/ AVPD, PTSD/BPD and Substance Use/BPD. Mean number of co-occurring PDs was 1.4; STPD had more than BPD group which had more than AVPD and OCPD groups. Significant PD co-occurrence emerged for: STPD/ Paranoid and Schizoid PDs, BPD with Antisocial and Dependent PDs, and lower frequency for OCPD/Antisocial PD.


CONCLUSIONS
Diagnostic co-occurrences generally followed base rates, while significant departures resemble those of controlled literature.
McGlashan
T H
TH
Yale Univeristy School of Medicine and Yale Psychiatric Institute and Department of Psychiatry, New Haven, CT 06520, USA.
Grilo
C M
CM
Skodol
A E
AE
Gunderson
J G
JG
Shea
M T
MT
Morey
L C
LC
Zanarini
M C
MC
Stout
R L
RL
D005500:Follow-Up Studies; D006801:Humans; D001523:Mental Disorders / Q000150:complications* / Q000175:diagnosis*; D010554:Personality Disorders / Q000150:complications* / Q000175:diagnosis*; D011569:Psychiatric Status Rating Scales; D015203:Reproducibility of Results; D012720:Severity of Illness Index