Radiocontrast Nephropathy.
The risk of developing radiocontrast nephropathy (RCN) is high in patients who are at risk, particularly those patients with diabetes and renal insufficiency. The development of RCN is associated with a significant increase in in-hospital mortality. RCN seems to develop as a result of dye-induced hypoperfusion of the renal medullary tubules. A variety of measures have been assessed to prevent the development of RCN, none more effective than saline hydration. Clinical evidence is now accumulating showing the potential to prevent RCN through the use of selective dopamine receptor agonists.
Lepor
NE
University of California Los Angeles School of Medicine, Cedars-Sinai Medical Towers, 8635 W. Third Street, #1190, Los Angeles, CA 90048, USA. Leporn@CSHS.org
Mathur
VS