title: Treatment of giant cell granuloma of the maxilla with intralesional injection of steroids.
abstract: BACKGROUND
  Giant cell granuloma is rare in the head and neck region and most commonly affects the maxilla and mandible. Although it is a benign disease process, it may be locally destructive. Surgery is the treatment currently recommended. Because of the location of the disease, surgery may be disfiguring. Because it is a benign process, less radical nonsurgical treatment alternatives are desirable.
  
  
  METHODS
  A case report of a giant cell granuloma treated with steroid injections.
  
  
  RESULTS
  After six weekly intralesional steroid injections, a giant cell granuloma of the maxilla became calcified and smaller. After a follow-up period of 2 years, there was no evidence of regrowth, and the bony osteolytic lesion had filled with bone. A review of the literature revealed two case reports of successful steroid injections with similar response.
  
  
  CONCLUSIONS
  Steroid injections are a viable alternative in the treatment of giant cell granuloma, which may avoid surgery.
authors.affiliation: Head and Neck Service, Department of Otolaryngology and Head and Neck Surgery, The University of Oklahoma Health and Sciences Center, 920 Stanton Young Blvd., Oklahoma City, Oklahoma 26901, USA.
authors.forename: A
authors.initials: A
authors.lastname: Khafif
authors.forename: G
authors.initials: G
authors.lastname: Krempl
authors.forename: J E
authors.initials: JE
authors.lastname: Medina
mesh_terms: D000328:Adult; D002045:Bupivacaine / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage*; D006101:Granuloma, Giant Cell / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D015552:Injections, Intralesional; D008441:Maxillary Neoplasms / Q000175:diagnosis / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014221:Triamcinolone / Q000008:administration & dosage*
chemical_list: D005938:Glucocorticoids; D014221:Triamcinolone; D002045:Bupivacaine