Nostocyclyne A, a novel antimicrobial cyclophane from the cyanobacterium Nostoc sp.
A novel acetylene-containing para-[14]-cyclophane, nostocyclyne A (1), possessing antimicrobial activity, is the major active metabolite of the natural bloom of the cyanobacterium Nostoc sp. (TAU strain IL-220). Homonuclear and heteronuclear 2D NMR techniques as well as HREIMS determined the gross structure of 1.
Ploutno
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A
School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel.
Carmeli
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D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D002851:Chromatography, High Pressure Liquid; D000458:Cyanobacteria / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D013055:Spectrophotometry, Infrared; D013210:Staphylococcus / Q000187:drug effects
D000900:Anti-Bacterial Agents