title: Large-scale enzymatic production of natural flavour esters in organic solvent with continuous water removal.
abstract: A new, large-scale process was developed for the enzymatic production of low molecular weight flavour esters in organic solvent. Solutions for the elimination of substrate and product inhibitions are presented. The excess water produced during the process was continuously removed by hetero-azeotropic distillation and esters were produced at yields of over 90%.
authors.affiliation: Research Institute of Chemical and Process Engineering, Kaposvar University, P.O. Box 125, H-8201, Veszprem, Hungary. gubicza@mukki.richem.hu
authors.forename: L
authors.initials: L
authors.lastname: Gubicza
authors.forename: A
authors.initials: A
authors.lastname: Kabiri-Badr
authors.forename: E
authors.initials: E
authors.lastname: Keoves
authors.forename: K
authors.initials: K
authors.lastname: Belafi-Bako
mesh_terms: D019342:Acetic Acid / Q000737:chemistry; D001709:Biotechnology / Q000379:methods; D020148:Butyric Acid / Q000737:chemistry; D002625:Chemistry, Organic / Q000379:methods; D004951:Esterification; D004952:Esters / Q000737:chemistry*; D019649:Food Industry / Q000379:methods*; D010865:Pilot Projects; D011422:Propionates / Q000737:chemistry; D012997:Solvents; D014867:Water / Q000737:chemistry*
chemical_list: D004952:Esters; D011422:Propionates; D012997:Solvents; D014867:Water; D020148:Butyric Acid; D019342:Acetic Acid