title: [Thrombin].
abstract: A survey of the present knowledge on the relationship between structure and biological activity of thrombin is made. The recent pharmacological research on the block of thrombin function is then evaluated.
authors.affiliation: Dipartimento di Medicina Interna, Università degli Studi, Pisa.
authors.forename: M
authors.initials: M
authors.lastname: Camici
authors.forename: A
authors.initials: A
authors.lastname: Sagripanti
authors.forename: R
authors.initials: R
authors.lastname: Di Mitri
mesh_terms: D000925:Anticoagulants / Q000494:pharmacology; D000990:Antithrombin III / Q000187:drug effects / Q000502:physiology; D001777:Blood Coagulation / Q000502:physiology; D005169:Factor VIII / Q000502:physiology; D005343:Fibrinolytic Agents / Q000494:pharmacology; D006493:Heparin / Q000494:pharmacology; D006495:Heparin, Low-Molecular-Weight / Q000494:pharmacology; D006801:Humans; D015539:Platelet Activation; D018179:Receptors, Thrombin / Q000187:drug effects; D012106:Research; D013917:Thrombin / Q000037:antagonists & inhibitors / Q000187:drug effects / Q000502:physiology
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D018179:Receptors, Thrombin; D000990:Antithrombin III; D005169:Factor VIII; D006493:Heparin; D013917:Thrombin