title: Spontaneous rupture of hepatocelluar carcinoma: surgical resection and long-term survival.
abstract: OBJECTIVE
  Spontaneous rupture of hepatocellular carcinoma (HCC) is a life-threatening event, particularly in patients with associated cirrhosis. We present our experience of hepatic resection of ruptured HCC.
  
  
  METHODS
  We performed 199 resections of hepatocellular carcinoma between January 1984 and December 1999. Six (3%) of these patients were operated on as an emergency because of haemoperitoneum: in five the liver was cirrhotic.
  
  
  RESULTS
  The mean duration of the operation was 195+/-101 min; all the patients received blood transfusions. The overall morbidity was 50%, with a mortality rate of 16.5%. Three patients were alive at 50, 80 and 116 months respectively; two had an intrahepatic recurrence treated by chemoembolization.
  
  
  CONCLUSIONS
  Non-surgical treatment of spontaneously ruptured hepatocarcinoma should be performed only in patients with contraindication to surgery. Hepatic resection should be the treatment of choice since, according to our experience, long-term results are similar to those of elective surgery.
authors.affiliation: First Surgical Department, 'Umberto I' Mauriziano Hospital, Torino, Italy. chirurgial@mauriziano.it
authors.forename: V
authors.initials: V
authors.lastname: Vergara
authors.forename: A
authors.initials: A
authors.lastname: Muratore
authors.forename: H
authors.initials: H
authors.lastname: Bouzari
authors.forename: R
authors.initials: R
authors.lastname: Polastri
authors.forename: A
authors.initials: A
authors.lastname: Ferrero
authors.forename: G
authors.initials: G
authors.lastname: Galatola
authors.forename: L
authors.initials: L
authors.lastname: Capussotti
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000601:surgery*; D016461:Chemoembolization, Therapeutic; D003131:Combined Modality Therapy; D004632:Emergency Medical Services; D005260:Female; D006465:Hemoperitoneum / Q000601:surgery; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012421:Rupture; D016019:Survival Analysis