title: [Circumscribed choroidal granulomatous inflammation after perforating injury. A histopathological study of four eyes].
abstract: BACKGROUND
  This study was performed to describe the clinicopathologic features of patients wo showed circumscribed choroidal granulomatous inflammation after trauma.
  
  
  METHODS
  We examined histologically 4 eyes which had been enucleated within 4 weeks after treatment for perforating trauma. The second eyes of the patients were not affected.
  
  
  RESULTS
  Four enucleated eyes with perforating injuries had focal uveal granulomatous inflammation of the posterior choroid. None of these eyes contained Dalen-Fuchs' nodules. One eye had a disrupted lens without lens-induced inflammation. All eyes exhibited choroidal ruptures. Foreign material could be detected in one of these eyes.
  
  
  CONCLUSIONS
  Focal choroidal granulomatous inflammation may occur as a result of penetrating ocular trauma. The origin of this condition is unknown, although a foreign body reaction and choroidal rupture may be involved in the pathogenesis of the granulomatous inflammation.
authors.affiliation: Universitäts-Augenklinik Heidelberg.
authors.forename: S
authors.initials: S
authors.lastname: Dithmar
authors.forename: H E
authors.initials: HE
authors.lastname: Völcker
authors.forename: H E
authors.initials: HE
authors.lastname: Grossniklaus
mesh_terms: D000328:Adult; D002648:Child; D002675:Child, Preschool; D002833:Choroiditis / Q000209:etiology* / Q000473:pathology; D015353:Eye Enucleation; D015807:Eye Injuries, Penetrating / Q000150:complications* / Q000473:pathology*; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male