Discorhabdin R: a new antibacterial pyrroloiminoquinone from two latrunculiid marine sponges, Latrunculia sp. and Negombata sp.
Two sponges belonging to the family Latrunculiidae (Negombata and Latrunculia sp.) collected during scientific trawling operations in Prydz Bay, Antarctica, and by scuba off Port Campbell, Victoria, have yielded a new antibacterial pyrroloiminoquinone, discorhabdin R (2). The structure was assigned as 2 on the basis of detailed spectroscopic analysis and comparison with the known co-metabolite discorhabdin B (3).
Ford
J
J
School of Chemistry, The University of Melbourne, Parkville, Victoria, 3010, Australia.
Capon
R J
RJ
D000818:Animals; D000864:Antarctic Regions; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D011161:Porifera / Q000737:chemistry*; D015363:Quinolones / Q000737:chemistry* / Q000302:isolation & purification; D011809:Quinones / Q000737:chemistry* / Q000302:isolation & purification; D013141:Spiro Compounds; D013841:Thiazepines / Q000737:chemistry* / Q000302:isolation & purification
D000890:Anti-Infective Agents; D015363:Quinolones; D011809:Quinones; D013141:Spiro Compounds; D013841:Thiazepines; C573536:discorhabdin B; C419723:discorhabdin R