title: US and CT findings in splenic focal lesions in AIDS.
abstract: OBJECTIVE
  To evaluate the role of US and CT in focal splenic lesions in AIDS patients in relation to etiology. MATERIAL AND METHODS; A total of 66 patients with AIDS and focal splenic lesions were examined with sonography. CT with administration of contrast medium was performed in 12 cases.
  
  
  RESULTS
  Of the focal splenic lesions, 67% were correlated with an infective pathology with prevalence of Mycobacteria tuberculosis (75%), 26% were neoplastic and 6% splenic infarcts. The lesions were hypoechoic in 60% of the cases, while 10% were hypoanechoic and 1% anechoic. At CT, all lesions appeared hypodense, even after i.v. administration of contrast medium.
  
  
  CONCLUSIONS
  The combination of echographic reports and clinical and laboratory data allows for a diagnosis that can be confirmed, and making a decision for effective therapy of AIDS is possible. CT does not provide any additional information.
authors.affiliation: Department of Radiology, National Institute for Infectious Diseases Lazzaro Spallanzani, Rome, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Schininà
authors.forename: E B
authors.initials: EB
authors.lastname: Rizzi
authors.forename: G
authors.initials: G
authors.lastname: Mazzuoli
authors.forename: V
authors.initials: V
authors.lastname: David
authors.forename: C
authors.initials: C
authors.lastname: Bibbolino
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D006801:Humans; D013154:Spleen / Q000000981:diagnostic imaging; D013158:Splenic Diseases / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography