title: Brimonidine and postoperative pressure spikes in cataract surgery.
abstract: OBJECTIVE
  To evaluate the efficacy of brimonidine in controlling postoperative pressure spikes following clear corneal cataract outpatient day surgery, in private practice in Australia.
  
  
  METHODS
  A prospective randomized trial was performed on 123 patients. Brimonidine 0.2% was instilled in the eyes 15 min prior to surgery, and intraocular pressure was checked 6 hours postoperatively.
  
  
  RESULTS
  Mean postoperative intraocular pressures at 6 hours were 30.33 mmHg in the treated group and 30.76 mmHg in the control group.
  
  
  CONCLUSIONS
  Brimonidine 0.2% instilled preoperatively offered no significant reduction in postoperative intraocular pressure spikes.
authors.affiliation: Forster Eye Surgery, NSW, Australia.
authors.forename: G
authors.initials: G
authors.lastname: Whitehouse
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000627:therapeutic use*; D000368:Aged; D000369:Aged, 80 and over; D000068438:Brimonidine Tartrate; D002387:Cataract Extraction / Q000009:adverse effects*; D004311:Double-Blind Method; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008875:Middle Aged; D009798:Ocular Hypertension / Q000188:drug therapy* / Q000209:etiology; D009883:Ophthalmic Solutions; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D011810:Quinoxalines / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000316:Adrenergic alpha-Agonists; D009883:Ophthalmic Solutions; D011810:Quinoxalines; D000068438:Brimonidine Tartrate