title: Cortical reafferentation following left subcortical hemorrhage: a serial functional MR study.
abstract: A 48-year-old patient who had aphasia due to a left subcortical hemorrhage underwent three follow-up examinations to assess MR signal changes accompanying recovery. A word classification task was applied. During the 6-month follow-up period, we observed a dynamic change from negative toward positive blood oxygenation level-dependent MR signals, i.e., task-related reafferentation of eloquent cortices occurred. Clinical improvement from aphasia paralleled the MR signal changes.
authors.affiliation: Max-Planck-Institute of Cognitive Neuroscience, Leipzig, Germany. hund@cns.mpg.de
authors.forename: M
authors.initials: M
authors.lastname: Hund-Georgiadis
authors.forename: U
authors.initials: U
authors.lastname: Lex
authors.forename: D G
authors.initials: DG
authors.lastname: Norris
authors.forename: D Y
authors.initials: DY
authors.lastname: von Cramon
mesh_terms: D001037:Aphasia / Q000209:etiology; D001921:Brain / Q000473:pathology* / Q000503:physiopathology; D001931:Brain Mapping; D002543:Cerebral Hemorrhage / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012660:Semantics