Exceptional familial clustering for extreme longevity in humans.
Four families highly clustered for extreme longevity are described here, representing the first report of clustering for this phenotype. Families such as these may prove to be helpful in the further understanding of the genetic contribution to achieving exceptional longevity.
Perls
T
T
Gerontology Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.
Shea-Drinkwater
M
M
Bowen-Flynn
J
J
Ridge
S B
SB
Kang
S
S
Joyce
E
E
Daly
M
M
Brewster
S J
SJ
Kunkel
L
L
Puca
A A
AA
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000235:genetics*; D016000:Cluster Analysis; D005190:Family; D005260:Female; D006801:Humans; D008136:Longevity / Q000235:genetics*; D008297:Male; D010641:Phenotype