title: The diagnostic and therapeutic impact of MRI: an observational multi-centre study.
abstract: OBJECTIVE
  To provide information about the diagnostic and therapeutic impact of magnetic resonance imaging (MRI) and to compare the findings across diagnostic groups.
  
  
  METHODS
  A prospective, observational study of 2017 consecutive referrals for MRI of the head, spine or knee at four imaging centres. Clinicians completed questionnaires before MRI stating initial diagnoses, diagnostic confidence and treatment plans. After imaging, a second questionnaire evaluated clinicians' revised diagnosis and treatment plans in the light of imaging findings. Patients were grouped into nine diagnostic categories for analysis. Comparison between pre- and post-imaging was used to assess the diagnostic and therapeutic impact of MRI.
  
  
  RESULTS
  In seven of nine diagnostic groups MRI findings were associated with a diagnostic impact. Diagnoses were revised or discarded following normal MR findings and diagnostic confidence was increased by confirmative MR findings. There was no statistically significant diagnostic impact for suspected pituitary or cerebello-pontine angle lesions. In five of nine diagnostic groups (knee meniscus, knee ligament, multiple sclerosis, lumbar and cervical spine) MRI findings had a clear impact on treatment plans.
  
  
  CONCLUSIONS
  This study demonstrates that in most diagnostic categories, MRI influences diagnosis and treatment. However, experimental studies are needed to prove that these diagnostic and therapeutic impacts lead to improved health.Hollingworth (2000). Clinical Radiology55, 825-831.
authors.affiliation: Health Services Research Group, Institute of Public Health, Cambridge, UK. wh108@medschl.cam.ac.uk
authors.forename: W
authors.initials: W
authors.lastname: Hollingworth
authors.forename: C J
authors.initials: CJ
authors.lastname: Todd
authors.forename: M I
authors.initials: MI
authors.lastname: Bell
authors.forename: Q
authors.initials: Q
authors.lastname: Arafat
authors.forename: S
authors.initials: S
authors.lastname: Girling
authors.forename: K R
authors.initials: KR
authors.lastname: Karia
authors.forename: A K
authors.initials: AK
authors.lastname: Dixon
mesh_terms: D006259:Craniocerebral Trauma / Q000175:diagnosis; D003627:Data Interpretation, Statistical; D003937:Diagnosis, Differential; D006801:Humans; D007718:Knee Injuries / Q000175:diagnosis; D008279:Magnetic Resonance Imaging / Q000592:standards* / Q000706:statistics & numerical data; D011446:Prospective Studies; D013122:Spinal Diseases / Q000175:diagnosis; D013124:Spinal Injuries / Q000175:diagnosis