[Phytoestrogens and SERMS, alternatives to classical hormone therapy?].
Isoprene is the main component of steroid hormones. It is found in many plants and herbal compounds, e.g. the isoflavonoids are therefore slightly estrogenic. Since they are bound to the estradiol receptors, more active estrogens cannot induce a signal transduction. Hence phytoestrogens may be protective on breast tissue and other hormone dependent organs.
Huber
J
J
Abteilung für Gynäkologische Endokrinologie und Sterilitätsbehandlung, Universitätsklinik für Frauenheilkunde Wien. johannes.huber@akh-wien.ac.at
D000368:Aged; D016588:Anticarcinogenic Agents / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000139:chemically induced / Q000517:prevention & control*; D015914:Estrogen Replacement Therapy / Q000379:methods*; D004968:Estrogens, Non-Steroidal / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D019833:Genistein / Q000627:therapeutic use; D006801:Humans; D007529:Isoflavones / Q000627:therapeutic use; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control*; D048789:Phytoestrogens; D028321:Plant Preparations; D017698:Postmenopause; D011960:Receptors, Estrogen / Q000819:agonists / Q000037:antagonists & inhibitors; D000077185:Resveratrol; D020845:Selective Estrogen Receptor Modulators / Q000494:pharmacology / Q000627:therapeutic use*; D013267:Stilbenes / Q000627:therapeutic use
D016588:Anticarcinogenic Agents; D004968:Estrogens, Non-Steroidal; D007529:Isoflavones; D048789:Phytoestrogens; D028321:Plant Preparations; D011960:Receptors, Estrogen; D020845:Selective Estrogen Receptor Modulators; D013267:Stilbenes; C004742:daidzein; D019833:Genistein; D000077185:Resveratrol