[Acute verapamil poisoning. A proposal of a strategy for therapeutic management].
Verapamil poisonings are rare, but are associated with a high proportion of deaths. The authors present a case of acute poisoning by verapamil associated with collapsus and a high degree of heart block. They propose a strategy for therapeutic management based on the study of calcium-channel blocker mechanisms of toxicity.
Lapostolle
F
F
Samu 93, hôpital Avicenne, Bobigny, France.
Bourdain
F
F
Adnet
F
F
Benaissa
A
A
Muszynski
J
J
Baud
F
F
D000208:Acute Disease; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D000368:Aged; D001285:Atropine / Q000627:therapeutic use; D002121:Calcium Channel Blockers / Q000506:poisoning*; D002316:Cardiotonic Agents / Q000627:therapeutic use; D004280:Dobutamine / Q000627:therapeutic use; D004837:Epinephrine / Q000627:therapeutic use; D005440:Fluid Therapy; D006327:Heart Block / Q000139:chemically induced; D006801:Humans; D007545:Isoproterenol / Q000627:therapeutic use; D008297:Male; D018727:Muscarinic Antagonists / Q000627:therapeutic use; D012769:Shock / Q000139:chemically induced; D016060:Sorption Detoxification; D014700:Verapamil / Q000506:poisoning*
D000318:Adrenergic beta-Agonists; D002121:Calcium Channel Blockers; D002316:Cardiotonic Agents; D018727:Muscarinic Antagonists; D004280:Dobutamine; D001285:Atropine; D014700:Verapamil; D007545:Isoproterenol; D004837:Epinephrine