Cell-mediated immune response during primary Chlamydia pneumoniae infection.
The development of Chlamydia pneumoniae-specific cell-mediated immunity was studied during a primary C. pneumoniae infection. The immune response was detected as positive lymphocyte proliferation and secretion of interferon gamma. C. pneumoniae-induced activation of both CD4(+) and CD8(+) T cells was detected in the early phase of infection, but activation of only CD4(+) T cells was detected in the later stage.
Halme
S
S
National Public Health Institute, University of Oulu, Oulu, Finland.
Latvala
J
J
Karttunen
R
R
Palatsi
I
I
Saikku
P
P
Surcel
H M
HM
D000293:Adolescent; D000328:Adult; D002690:Chlamydia Infections / Q000276:immunology*; D002692:Chlamydia trachomatis; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D007371:Interferon-gamma / Q000096:biosynthesis; D016753:Interleukin-10 / Q000096:biosynthesis; D008213:Lymphocyte Activation; D008297:Male
D006684:HLA-DR Antigens; D016753:Interleukin-10; D007371:Interferon-gamma