Amyloid in a multiple sclerosis lesion in clearly of Alambda type.
In rare multiple sclerosis cases amyloid is deposited in demyelinated plaques. In one such case amyloid was examined immunohistochemically with a panel of antibodies directed against different amyloid types. The amyloid was classified as the Alambda type produced by a local monoclonal B cell population.
Schröder
R
R
Institute of Pathology, Neuropathology, University of Cologne, Köln, Germany.
Nennesmo
I
I
Linke
R P
RP
D000686:Amyloidosis / Q000150:complications / Q000378:metabolism / Q000473:pathology; D002536:Cerebral Arteries / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications* / Q000378:metabolism / Q000473:pathology*; D058225:Plaque, Amyloid / Q000378:metabolism* / Q000473:pathology*; D000685:Serum Amyloid A Protein / Q000378:metabolism*
D000685:Serum Amyloid A Protein