title: [The effectiveness of prenatal steroid and ambroxol therapy for the prevention of respiratory distress syndrome in newborns of diabetic mothers].
abstract: The aim of the study was to determine the effectiveness of antenatal steroids and ambroxol in reduction of respiratory distress syndrome (RDS) in newborns of diabetic mothers. A retrospective chart review was done on 101 diabetic gravidas who were hospitalised at 1st Department of Obstetrics and Gynaecology Medical University in Warsaw between January 1989 and December 1999. We studied the neonatal outcomes for women with diabetes mellitus who delivered before 37 gestational weeks depend on exposition to antenatal steroids or ambroxol. Both groups were compared with unexposed neonates for respiratory distress syndrome. Frequency of occurrence and severity of RDS were similar in all study subgroups. We did not found reduction of respiratory distress syndrome in newborns of diabetic mothers exposed to antenatal steroids or ambroxol.
authors.affiliation: I Katedry i Kliniki Połoznictwa i Ginekologii AM w Warszawie.
authors.forename: D A
authors.initials: DA
authors.lastname: Bomba-Opoń
authors.forename: A
authors.initials: A
authors.lastname: Wiczyńska-Zajac
authors.forename: E
authors.initials: E
authors.lastname: Domańska-Janczewska
authors.forename: B
authors.initials: B
authors.lastname: Kociszewska-Najman
authors.forename: L
authors.initials: L
authors.lastname: Marianowski
mesh_terms: D000328:Adult; D000551:Ambroxol / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003922:Diabetes Mellitus, Type 1; D005100:Expectorants / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011254:Pregnancy in Diabetics; D011295:Prenatal Care; D012120:Respiration Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D012720:Severity of Illness Index; D013256:Steroids
chemical_list: D000893:Anti-Inflammatory Agents; D005100:Expectorants; D013256:Steroids; D000551:Ambroxol