title: Genetic control of biogenic-amine systems in Drosophila under normal and stress conditions.
abstract: The contents of octopamine and its precursors (tyrosine and tyramine) were studied in adults of two lines of Drosophila virilis with contrasting stress responses. It was demonstrated that in individuals responding to stress by a hormonal stress reaction (line 101), the contents of octopamine and tyrosine are lower than in nonresponding flies (line 147). It was found that there is no difference between the lines in the level of tyramine under normal conditions. The dopamine response to stressor was also studied. Genetic analysis of these differences revealed that they are controlled by a single gene and that the gene is not sex-linked. The gene controlling the response was found to be linked to chromosome 6 of D. virilis.
authors.affiliation: Division of Bioresource and Bioenvironmental Sciences, Graduate School, Kyushu University, Fukuoka, Japan. ahirasim@agr.kyushu-u.ac.jp
authors.forename: A
authors.initials: A
authors.lastname: Hirashima
authors.lastname: Sukhanova MJh
authors.lastname: Rauschenbach IYu
mesh_terms: D000818:Animals; D001679:Biogenic Amines / Q000378:metabolism*; D002875:Chromosomes / Q000235:genetics; D003433:Crosses, Genetic; D004298:Dopamine / Q000378:metabolism; D004330:Drosophila / Q000235:genetics* / Q000378:metabolism*; D005260:Female; D005786:Gene Expression Regulation; D008040:Genetic Linkage; D018869:Heat-Shock Response / Q000235:genetics*; D008297:Male; D009154:Mutation; D009655:Octopamine / Q000378:metabolism; D014439:Tyramine / Q000378:metabolism; D014443:Tyrosine / Q000378:metabolism
chemical_list: D001679:Biogenic Amines; D009655:Octopamine; D014443:Tyrosine; D004298:Dopamine; D014439:Tyramine