Recreational use of aminorex and pulmonary hypertension.
Pulmonary hypertension has been associated with ingestion of the appetite suppressant aminorex. A similar compound, 4-methyl-aminorex (street names, "U-4-E-uh" [pronounced euphoria] or "ice"), is a "designer" drug with central stimulant activity. This drug was discovered on the property of three individuals with diagnoses of pulmonary hypertension. The association between "recreational" aminorex manufacture and ingestion and the development of pulmonary hypertension is described.
Gaine
S P
SP
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA.
Rubin
L J
LJ
Kmetzo
J J
JJ
Palevsky
H I
HI
Traill
T A
TA
D000328:Adult; D000635:Aminorex / Q000009:adverse effects*; D001067:Appetite Depressants / Q000009:adverse effects*; D000697:Central Nervous System Stimulants / Q000009:adverse effects; D015198:Designer Drugs; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000139:chemically induced*; D013287:Illicit Drugs / Q000009:adverse effects*; D008297:Male; D010080:Oxazoles / Q000009:adverse effects*; D019966:Substance-Related Disorders
D001067:Appetite Depressants; D000697:Central Nervous System Stimulants; D015198:Designer Drugs; D013287:Illicit Drugs; D010080:Oxazoles; D000635:Aminorex; C000081:4-methylaminorex