title: [Primary central nervous system malignant lymphoma originating from the cerebellum and extending along the lower cranial nerves].
abstract: We report a case of primary central nervous system (CNS) malignant lymphoma of the central nervous system originating from the cerebellum and growing along the lower cranial nerves. A 67-year-old woman presented with hoarseness, vertigo, nausea, and vomiting. Gd-DTPA enhanced MRI showed a homogeneous enhanced mass lesion extending from the cerebellum to the medulla oblongata around the jugular foramen on the right side. Although pre- and intra-operative diagnosis had been schwannoma, histopathological examination revealed a B-cell, diffuse malignant lymphoma. The growth pattern of malignant lymphoma in the present case, which extended extra-axially, is considered to be rare. We discuss here the growth patterns and difficulties of diagnosis of primary CNS malignant lymphoma in this area.
authors.affiliation: Department of Neurosurgery, Ushiku-Aiwa General Hospital, Tokyo, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Sasahara
authors.forename: T
authors.initials: T
authors.lastname: Kawamata
authors.forename: O
authors.initials: O
authors.lastname: Kubo
authors.forename: N
authors.initials: N
authors.lastname: Okami
authors.forename: H
authors.initials: H
authors.lastname: Kawamura
authors.forename: T
authors.initials: T
authors.lastname: Hori
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001921:Brain / Q000473:pathology; D016543:Central Nervous System Neoplasms / Q000473:pathology* / Q000601:surgery; D002528:Cerebellar Neoplasms / Q000473:pathology* / Q000601:surgery; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D003390:Cranial Nerve Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000473:pathology* / Q000601:surgery; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging