title: Is alexithymia a permanent feature in depressed patients? Results from a 6-month follow-up study.
abstract: BACKGROUND
  A six-month follow-up study was conducted to determine whether alexithymia is a permanent feature in 169 depressed outpatients.
  
  
  METHODS
  Diagnosis of depression was confirmed by means of the Structured Clinical Interview for DSM-III-R (SCID-I). Alexithymia was screened using the 20-item version of the Toronto Alexithymia Scale (TAS-20) and severity of depression was assessed using the 21-item Beck Depression Inventory (BDI).
  
  
  RESULTS
  Almost 40% of the patients were considered alexithymic at baseline, but only 23% at follow-up. Alexithymic patients were more often moderately or severely depressed than other patients in both study phases. The BDI scores explained 23% (at baseline) and 42% (at follow-up) of the variation in TAS-20 scores. The decrease in the TAS-20 scores was associated with a concurrent decrease in BDI scores.
  
  
  CONCLUSIONS
  Alexithymic patients with depressive disorders do not appear to form a stable group. On the contrary, alexithymia seems to change as a function of depression. In the light of these results, alexithymia appears not to be a stable personality trait among depressed patients, and furthermore, it seems possible that alexithymic features respond to psychiatric treatment.
authors.affiliation: Department of Psychiatry, Research and Development Unit, Kuopio University Hospital, Kuopio, Finland. kirsi.honkalampi@kuh.fi
authors.forename: K
authors.initials: K
authors.lastname: Honkalampi
authors.forename: J
authors.initials: J
authors.lastname: Hintikka
authors.forename: P
authors.initials: P
authors.lastname: Saarinen
authors.forename: J
authors.initials: J
authors.lastname: Lehtonen
authors.forename: H
authors.initials: H
authors.lastname: Viinamäki
mesh_terms: D000328:Adult; D000342:Affective Symptoms / Q000523:psychology*; D003866:Depressive Disorder / Q000150:complications / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index