A common enzyme connects notch signaling and Alzheimer's disease.
Kopan
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Department of Pharmacology and Molecular Biology, Departments of Psychiatry and Genetics, Washington University School of Medicine, St. Louis, Missouri 63110, USA. kopan@molecool.wustl.edu
Goate
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D000544:Alzheimer Disease / Q000201:enzymology*; D010450:Endopeptidases / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism*; D053764:Presenilin-1; D053766:Presenilin-2; D011956:Receptors, Cell Surface / Q000378:metabolism*; D051880:Receptors, Notch; D015398:Signal Transduction
D008565:Membrane Proteins; D053764:Presenilin-1; D053766:Presenilin-2; D011956:Receptors, Cell Surface; D051880:Receptors, Notch; D010450:Endopeptidases