Mechanisms underlying urticaria.
Urticaria, a clinically distressing disorder, is dermal oedema resulting from vascular dilatation and leakage of fluid into surrounding tissue, often in response to histamine (and other mediators) released from mast cells. A clear history of events surrounding the onset, together with laboratory investigations, in some cases allows us to find a cause and eliminate it.
Powell
J
J
Department of Dermatology, Churchill Hospital, Headington, Oxford.
Powell
S
S
D000208:Acute Disease; D000293:Adolescent; D000799:Angioedema / Q000209:etiology / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D006801:Humans; D006967:Hypersensitivity / Q000150:complications* / Q000276:immunology; D007223:Infant; D007231:Infant, Newborn; D008407:Mast Cells / Q000502:physiology; D014581:Urticaria / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology