Catalytic antibodies: generation, nature, and possible role as chemical warfare scavengers.
Nearly three decades have passed since the idea was proposed that antibodies may provide catalytic activity as enzymes. Since then the term "catalytic antibodies" has gained more and more popularity. Numerous antibodies enhancing the rate of reactions have been described. This review will address the basic biological considerations involved in the genesis of catalytic antibodies and explore their possible role in the future providing protection in chemical warfare.
Amital
H
H
Department of Medicine B, Sheba Medical Center, Tel-Hashomer, Sackler Faculty of Medicine, Tel-Aviv University, Israel.
Tur-Kaspa
I
I
Tashma
Z
Z
Hendler
I
I
Shoenfeld
Y
Y
D017151:Antibodies, Catalytic / Q000494:pharmacology* / Q000627:therapeutic use*; D002619:Chemical Warfare Agents / Q000506:poisoning*; D005544:Forecasting; D006801:Humans; D007306:Insecticides / Q000506:poisoning; D008887:Military Medicine / Q000639:trends; D009943:Organophosphorus Compounds; D011041:Poisoning / Q000628:therapy
D017151:Antibodies, Catalytic; D002619:Chemical Warfare Agents; D007306:Insecticides; D009943:Organophosphorus Compounds