title: [Fulminant necrotizing fasciitis secondary to Crohn's disease].
abstract: Necrotizing fasciitis is a life-threatening infection, commonly caused by group A streptococci, which has to be treated by surgical exploration and debridement during the first 24 h. Clinical clues are severe pain, in some cases followed by the appearance of bullous formations, and the detection of gas in the soft tissues by computed tomography or MRI. In addition to that, the infection is characterized by rapid inflammatory progression, producing a highly life-threatening situation. Diagnosis is finally based on surgical exploration obtaining specimens for culture and histopathologic examination. Debridement and exploration, in some cases amputation of the extremity, are indicated as soon as possible. Antibiotic therapy increases efficacy too, but there is no substitute for surgical treatment. Inflammatory bowel disease (Crohn's disease in this case) followed by necrotizing fasciitis is rarely mentioned in the literature. Therapeutic management in a situation of immunosuppression is discussed by illustration of an actual case.
authors.affiliation: Klinik und Poliklinik für Allgemeinchirurgie, Westfälische Wilhelms-Universität, Münster.
authors.forename: M
authors.initials: M
authors.lastname: Neuber
authors.forename: H
authors.initials: H
authors.lastname: Rieger
authors.forename: M
authors.initials: M
authors.lastname: Brüwer
authors.forename: C
authors.initials: C
authors.lastname: Poremba
authors.forename: G
authors.initials: G
authors.lastname: Winde
mesh_terms: D000328:Adult; D002081:Buttocks; D003424:Crohn Disease / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D004927:Escherichia coli Infections / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000601:surgery; D005205:Fascia / Q000473:pathology; D019115:Fasciitis, Necrotizing / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D000071938:Fasciotomy; D005260:Female; D006801:Humans; D007077:Ileal Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D007412:Intestinal Fistula / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D013290:Streptococcal Infections / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed