title: [The generalist and immunosuppressive agents].
abstract: The general practioneer is frequently concerned by the follow-up of patients receiving immunosuppressive agents for auto-immune diseases or for the prevention of graft rejection. We here review the side effects of the most frequently used immunosuppressive drugs: glucocorticoids, azathioprine, cyclophophamide, cyclosporine and methotrexate. Important drug interactions are also mentioned. We also discuss the adult vaccine schedule for patients treated with immunosuppressive agents. Finally, the consequences of immunosuppressive drugs on fertility and pregnancy are developed.
authors.affiliation: Service de Médecine Interne Générale, Hôpital Erasme, U.L.B.
authors.forename: E
authors.initials: E
authors.lastname: Cogan
mesh_terms: D000328:Adult; D004334:Drug Administration Schedule; D004347:Drug Interactions; D016903:Drug Monitoring / Q000379:methods; D005194:Family Practice / Q000379:methods*; D005260:Female; D005298:Fertility / Q000187:drug effects; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology; D007166:Immunosuppressive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D011247:Pregnancy / Q000187:drug effects; D014611:Vaccination
chemical_list: D007166:Immunosuppressive Agents