title: Monitoring gas exchange during a constant work rate exercise in patients with left ventricular dysfunction treated with carvedilol.
abstract: In patients with heart failure, carvedilol ameliorated cardiac function, but it did not affect oxygen uptake, kinetics, and ventilatory efficiency during 6-minute exercise at a constant 50-W workload. Persistence of respiratory incompetence may prevent improvement in submaximal oxygen uptake kinetics.
authors.affiliation: Istituto di Cardiologia dell Universitá degli Studi, Centro di Studio per le Richerche Cardiovascolari del Consiglio Nazionale delle Ricerche, Milan, Italy. mguazzi@cardiologicomonzino.it
authors.forename: M
authors.initials: M
authors.lastname: Guazzi
authors.forename: P G
authors.initials: PG
authors.lastname: Agostoni
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D002227:Carbazoles / Q000627:therapeutic use*; D000077261:Carvedilol; D004311:Double-Blind Method; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011412:Propanolamines / Q000627:therapeutic use*; D011659:Pulmonary Gas Exchange / Q000187:drug effects*; D013997:Time Factors; D018487:Ventricular Dysfunction, Left / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D000319:Adrenergic beta-Antagonists; D002227:Carbazoles; D011412:Propanolamines; D000077261:Carvedilol