title: Sequential evaluation of left ventricular myocardial performance in children after anthracycline therapy.
abstract: This study prospectively assessed subclinical cardiotoxicity in patients undergoing chemotherapy by using the Tei index combining systolic and diastolic time intervals. A significant difference in the Tei index was observed between patients who received a low dose and those who received a moderate to high dose of anthracycline antibiotic drugs. The Tei index is a sensitive, accurate, and easy approach for detecting subclinical anthracycline cardiotoxicity.
authors.affiliation: Department of Pediatrics and the Cardiovascular Research Institute, Kurume University School of Medicine, Japan. masaishi@med.kurume-u.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Ishii
authors.forename: T
authors.initials: T
authors.lastname: Tsutsumi
authors.forename: W
authors.initials: W
authors.lastname: Himeno
authors.forename: G
authors.initials: G
authors.lastname: Eto
authors.forename: J
authors.initials: J
authors.lastname: Furui
authors.forename: K
authors.initials: K
authors.lastname: Hashino
authors.forename: Y
authors.initials: Y
authors.lastname: Sugahara
authors.forename: H
authors.initials: H
authors.lastname: Muta
authors.forename: T
authors.initials: T
authors.lastname: Akagi
authors.forename: A
authors.initials: A
authors.lastname: Ando
authors.forename: H
authors.initials: H
authors.lastname: Eguchi
authors.forename: H
authors.initials: H
authors.lastname: Kato
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D001783:Blood Flow Velocity / Q000187:drug effects; D002648:Child; D015150:Echocardiography, Doppler; D006801:Humans; D008479:Mediastinal Neoplasms / Q000188:drug therapy*; D009200:Myocardial Contraction / Q000187:drug effects; D015588:Observer Variation; D011379:Prognosis; D011446:Prospective Studies; D013318:Stroke Volume / Q000187:drug effects; D018487:Ventricular Dysfunction, Left / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000503:physiopathology*
chemical_list: D000903:Antibiotics, Antineoplastic