[Glutathione peroxidase concentration in the peritoneal fluid from infertile women].
OBJECTIVE
To assess the concentration of Plasma Glutathione Peroxidase (plGPx) in the peritoneal fluid (PF) of patients with unexplained infertility and infertile women with minimal and mild endometriosis.


METHODS
33 women were studied, including 8 infertile women with minimal or mild endometriosis, 15 patients with unexplained infertility and 10 patients with tubal occlusion (a reference group). Concentration of plGPx was measured in the PF using a commercially available ELISA kit (Oxis Inc.).


RESULTS
The plGPx concentration was significantly (p = 0.04) lower in PF from women with unexplained infertility (846 +/- 177 ng/ml) compared to the reference group (1023 +/- 238 ng/ml), but did not differ significantly (p = 0.25) between women with endometriosis (918 +/- 81 ng/ml) and patients with tubal infertility.


CONCLUSIONS
Our results suggest that low peritoneal plGPx concentration may play a role in the pathogenesis of infertility.
Polak
G
G
Katedry i Zakładu Mikrobiologii Lekarskiej AM w Lublinie.
Kozioł-Montewka
M
M
Tarkowski
R
R
Morawska
D
D
Kotarski
J
J
D000328:Adult; D001202:Ascitic Fluid / Q000737:chemistry*; D004715:Endometriosis / Q000150:complications; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005979:Glutathione Peroxidase / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D007247:Infertility, Female / Q000201:enzymology* / Q000209:etiology
D005979:Glutathione Peroxidase