title: Distribution of a common methylenetetrahydrofolate mutation in six Chinese population groups.
abstract: The distribution of the C677T polymorphism was analyzed by the PCR-RFLP technique in the Northeast Han, the Oroqen, the Ewenki, the Daur as well as in Koreans and Mongolians. The results were compared with each other. They revealed that the frequencies of the T allele are quite different (17-47%) among the tested groups and are much higher in Chinese population groups than in others.
authors.affiliation: Department of Medical Genetics, Harbin Medical University, China. xueyl@ems.hrbmu.edu.cn
authors.forename: Y
authors.initials: Y
authors.lastname: Xue
authors.forename: J
authors.initials: J
authors.lastname: Yu
authors.forename: Q
authors.initials: Q
authors.lastname: Wan
authors.forename: S
authors.initials: S
authors.lastname: Fu
authors.forename: F
authors.initials: F
authors.lastname: Cheng
authors.forename: C
authors.initials: C
authors.lastname: Huang
authors.forename: G
authors.initials: G
authors.lastname: Zhang
authors.forename: P
authors.initials: P
authors.lastname: Li
mesh_terms: D044466:Asian People / Q000235:genetics*; D002681:China; D005787:Gene Frequency / Q000235:genetics; D005828:Genetics, Population; D006801:Humans; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D009154:Mutation / Q000235:genetics*; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D000587:Oxidoreductases Acting on CH-NH Group Donors; D042965:Methylenetetrahydrofolate Reductase (NADPH2)