Asymmetric synthesis of the core structure of (-)-CP-263,114.
The enantioselective construction of a fully functionalized core structure of (-)-CP-263,114 (1), containing most of the required functionality for total synthesis, was conducted through sequential radical fragmentation-reductive olefination.
Yoshimitsu
T
T
Meiji Pharmaceutical University, Noshio, Kiyose, Tokyo 204-8588, Japan. takey@my-pharm.ac.jp
Yanagisawa
S
S
Nagaoka
H
H
D004791:Enzyme Inhibitors / Q000138:chemical synthesis*; D005609:Free Radicals; D008299:Maleic Anhydrides / Q000138:chemical synthesis*; D010084:Oxidation-Reduction; D013237:Stereoisomerism
C104957:CP 263114; D004791:Enzyme Inhibitors; D005609:Free Radicals; D008299:Maleic Anhydrides