title: Pure primary choriocarcinoma of the urinary bladder with long-term survival.
abstract: Choriocarcinoma was diagnosed in a 77-year-old woman with an acute massive, painless hematuria. One year after anterior pelvic exenteration and ileal conduit, the beta-human chorionic gonadotropin level increased to 934 mIU/mL without any sign of tumor progression. After six courses of chemotherapy (vincristine, actinomycin, and cyclophosphamide), the beta-human chorionic gonadotropin levels returned to normal. To our knowledge, this is the fourth case of pure choriocarcinoma in the bladder, with the longest survival time of 33 months so far.
authors.affiliation: Department of Urology, Westfälische Wilhelms University, Münster, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Sievert
authors.forename: E A
authors.initials: EA
authors.lastname: Weber
authors.forename: R
authors.initials: R
authors.lastname: Herwig
authors.forename: H
authors.initials: H
authors.lastname: Schmid
authors.forename: S
authors.initials: S
authors.lastname: Roos
authors.forename: H U
authors.initials: HU
authors.lastname: Eickenberg
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002822:Choriocarcinoma / Q000175:diagnosis / Q000628:therapy*; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000032:analysis; D003520:Cyclophosphamide / Q000008:administration & dosage; D003609:Dactinomycin / Q000008:administration & dosage; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000628:therapy; D018365:Neoplasm, Residual / Q000188:drug therapy; D012086:Reoperation; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000628:therapy*; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D018997:Chorionic Gonadotropin, beta Subunit, Human; D003609:Dactinomycin; D014750:Vincristine; D003520:Cyclophosphamide