[Algorithm of immunomorphological criteria of diagnosis of gastric mucosa dysplasias and early cancer in stomach biopsies].
Indices of systemic and local immunity of gastric mucosa were studied in patients with chronic gastritis (n = 27), epithelial dysplasia of gastric mucosa (n = 13), early gastric carcinoma (n = 9) and advanced gastric carcinoma (n = 6). Local immunity was estimated by calculation of lymphocytes and plasma cells expressing IgA and IgM in the epithelium of stomach mucosa. Systemic immunity was studied by radial diffusion according to Manchini's method. This approach provides objectivization of morphological results, particularly in endoscopic biopsies, and therefore to improvement of the patient examination and diagnosis of early cancer.
Khmel'nitskiĭ
O K
OK
St-Petersburg Medical Academy of Postgraduate Education.
Sarantsev
B V
BV
D000465:Algorithms; D000917:Antibody Formation; D001706:Biopsy; D005753:Gastric Mucosa / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007111:Immunity, Cellular; D011230:Precancerous Conditions / Q000276:immunology / Q000473:pathology*; D011379:Prognosis; D013274:Stomach Neoplasms / Q000276:immunology / Q000401:mortality / Q000473:pathology*