title: Intraocular pressure variation following retrobulbar anaesthesia among the different sex, age and ethnic groups in Malaysia.
abstract: A total of 114 patients (48 Chinese, 34 Malay and 32 Indian) undergoing extracapsular cataract extraction (ECCE) with intraocular lens implantation, were enrolled. All were given 3 ml of local anaesthetic (combination of equal amounts of lignocaine 2% and bupivacaine 0.5%) using retrobulbar technique. Intraocular pressure (IOP) was measured at different time intervals; before, immediately after and 5 minutes after injection with Honan balloon compression. Mean IOP increased by 5.0 mmHg immediately after injection (p < 0.001) and reduced to baseline level after 5 minutes of external compression. Although there were no statistical difference in terms of IOP variation between sex and age groups, Chinese patients demonstrated the highest IOP rise following retrobulbar anaesthesia. This is the first study to demonstrate the influence of race in the IOP response with Chinese subjects having the highest IOP rise.
authors.affiliation: Department of Ophthalmology, University Malaya, Kuala Lumpur.
authors.forename: F N
authors.initials: FN
authors.lastname: Lee
authors.forename: V Y
authors.initials: VY
authors.lastname: Kong
authors.forename: G P
authors.initials: GP
authors.lastname: Lee
authors.forename: K H
authors.initials: KH
authors.lastname: Ho
authors.forename: S C
authors.initials: SC
authors.lastname: Choon
authors.forename: H B
authors.initials: HB
authors.lastname: Hoh
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D000779:Anesthetics, Local / Q000008:administration & dosage* / Q000009:adverse effects*; D002387:Cataract Extraction; D002681:China / Q000208:ethnology; D005260:Female; D006801:Humans; D007194:India / Q000208:ethnology; D007267:Injections / Q000009:adverse effects; D007429:Intraocular Pressure / Q000187:drug effects*; D007910:Lenses, Intraocular; D008296:Malaysia; D008297:Male; D008875:Middle Aged; D012727:Sex Characteristics
chemical_list: D000779:Anesthetics, Local