title: Successful in situ treatment of an infected ascending aortic graft.
abstract: Infection of an ascending aortic prosthesis is a grave complication associated with a high mortality. In most cases, extraanatomic bypass and removal of the infected vascular graft are not possible. Furthermore, the standard approach to this problem, which includes excision and replacement or debridement and repair of infected thoracic aortic grafts, carries a high early mortality. We report the successful treatment of this life-threatening complication using a conservative strategy in which the aortic prosthesis was salvaged by in situ disinfection followed by coverage with tissue flaps.
authors.affiliation: Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.
authors.forename: D W
authors.initials: DW
authors.lastname: Mathes
authors.forename: M J
authors.initials: MJ
authors.lastname: Yaremchuk
authors.forename: E M
authors.initials: EM
authors.lastname: Isselbacher
authors.forename: J C
authors.initials: JC
authors.lastname: Madsen
mesh_terms: D000328:Adult; D000784:Aortic Dissection / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000601:surgery*; D011206:Povidone-Iodine / Q000008:administration & dosage; D016459:Prosthesis-Related Infections / Q000601:surgery*; D011512:Proteus Infections / Q000601:surgery*; D011514:Proteus vulgaris; D012086:Reoperation; D013524:Surgical Flaps; D013530:Surgical Wound Infection / Q000601:surgery; D007507:Therapeutic Irrigation
chemical_list: D011206:Povidone-Iodine