title: Topoisomerase II-mediated cleavage of plasmid DNA.
authors.affiliation: Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA.
authors.forename: D A
authors.initials: DA
authors.lastname: Burden
authors.forename: S J
authors.initials: SJ
authors.lastname: Froelich-Ammon
authors.forename: N
authors.initials: N
authors.lastname: Osheroff
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology; D004250:DNA Topoisomerases, Type II / Q000378:metabolism*; D004269:DNA, Bacterial / Q000737:chemistry / Q000378:metabolism; D004278:DNA, Superhelical / Q000737:chemistry / Q000378:metabolism; D004331:Drosophila melanogaster / Q000201:enzymology; D004587:Electrophoresis, Agar Gel; D005047:Etoposide / Q000494:pharmacology; D009690:Nucleic Acid Conformation / Q000187:drug effects; D010957:Plasmids / Q000737:chemistry / Q000378:metabolism*; D059005:Topoisomerase II Inhibitors
chemical_list: D000970:Antineoplastic Agents; D004269:DNA, Bacterial; D004278:DNA, Superhelical; D059005:Topoisomerase II Inhibitors; D005047:Etoposide; D004250:DNA Topoisomerases, Type II