title: [Evaluation of resting energy expenditure in children with cystic fibrosis].
abstract: The aim of the investigation was to assess resting energy expenditure (REE) and substrate utilisation rate in children with cystic fibrosis. Body mass coefficient was below normal limits in 2 out of 14 controls and in 9 out of 10 patients with cystic fibrosis (p < 0.001). REE and basal energy expenditure (BEE) in the patient group were respectively 52.2 +/- 8.7 kcal/kg and 45.7 +/- 8.9 kcal/kg (p < 0.006). REE/BEE ratios in relation to total body mass were 115.34 +/- 12.27% and 93.54 +/- 4.47% (p < 0.001). REE / BEE ratio in relation to lean body mass 102.95 +/- 11.5% and 92.94 +/- 5.74% (p < 0.007). Substrate oxidation rate in the patient group and control group (g/kg) were: glycogen: 4.13 +/- 2.32 and 1.91 +/- 0.81 (p < 0.004); fat: 2.76 +/- 1.39 and 1.51 +/- 0.59 (p < 0.006); protein: 1.98 +/- 0.45 and 1.32 +/- 0.40 (p < 0.001).
  
  
  CONCLUSIONS
  In children with cystic fibrosis, malnutrition was found with increase REE which resulted from higher substrate utilisation rate as compared with the control group.
authors.affiliation: Klinika Pediatrii, Instytut Matki i Dziecka, Kasprzaka 17a, 01-211, Warszawa, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Ksiazyk
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications / Q000503:physiopathology*; D004734:Energy Metabolism / Q000502:physiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009748:Nutrition Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology