title: Trichophyton tonsurans tinea capitis and tinea corporis: treatment and follow-up of four affected family members.
abstract: We report a Caucasian family of two veterinary practitioners and their two children, ages 2 years and 6 months, simultaneously infected with the dermatophyte Trichophyton tonsurans, causing tinea capitis and tinea corporis in the children and tinea corporis in the parents. The parents and older child were successfully treated with oral terbinafine. The infant clinically responded to treatment with topical terbinafine and ketoconazole shampoo but presented with recurrent tinea capitis 12 months later, from which T. tonsurans was cultured. At this time, scalpbrush samples from the other family members failed to culture any fungi, and neither were fungi isolated from the family hairbrushes. The infant then received oral terbinafine, resulting in clinical and mycologic cure. After a further 12 months follow-up, there has been no mycologic evidence of recurrence in any family member.
authors.affiliation: Department of Dermatology, Leeds General Infirmary, West Yorkshire, England. ravo@compuserve.com
authors.forename: J
authors.initials: J
authors.lastname: Ravenscroft
authors.forename: M J
authors.initials: MJ
authors.lastname: Goodfield
authors.forename: E G
authors.initials: EG
authors.lastname: Evans
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002675:Child, Preschool; D005190:Family; D005260:Female; D006801:Humans; D007223:Infant; D007654:Ketoconazole / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D009281:Naphthalenes / Q000008:administration & dosage / Q000627:therapeutic use*; D012008:Recurrence; D000077291:Terbinafine; D014005:Tinea / Q000628:therapy; D014006:Tinea Capitis / Q000175:diagnosis / Q000628:therapy* / Q000635:transmission; D014249:Trichophyton / Q000302:isolation & purification*
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine; D007654:Ketoconazole