Increase of macrophage migration inhibitory factor in sera of patients with iridocyclitis.
OBJECTIVE
To determine whether macrophage migration inhibitory factor (MIF) levels were increased in sera of the patients with iridocyclitis.


METHODS
Sera were obtained from 41 patients with acute iridocyclitis, 13 patients with chronic iridocyclitis, and 44 healthy control subjects. MIF levels were determined by a human MIF ELISA.


RESULTS
The average levels of MIF in the sera of patients with both acute and chronic iridocyclitis were significantly higher than that of healthy subjects.


CONCLUSIONS
Uveitis induces the elevation of serum MIF, which may affect various inflammatory symptoms in uveitis.
Kitaichi
N
N
Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Japan.
Kotake
S
S
Mizue
Y
Y
Matsuda
H
H
Onoé
K
K
Nishihira
J
J
D000208:Acute Disease; D002908:Chronic Disease; D005260:Female; D006801:Humans; D015863:Iridocyclitis / Q000097:blood*; D008263:Macrophage Migration-Inhibitory Factors / Q000097:blood*; D008297:Male
D008263:Macrophage Migration-Inhibitory Factors