Difference in fibrinolytic activity between multivessel coronary spasm and one-vessel coronary spasm.
Plasminogen activator inhibitor activity was higher in 18 patients with multivessel spasm than in 20 patients with 1-vessel spasm and in 22 control patients. Tissue plasminogen activator antigen was also higher in patients with multivessel spasm than in those with 1-vessel spasm and control patients. The increased plasminogen activator inhibitor activity in patients with multivessel spasm indicates that the fibrinolytic system is more impaired in such patients than in those with 1-vessel coronary spasm; this may be related to the higher incidence of refractory angina during hospitalization and cardiac events during the follow-up period.
Ogawa
H
H
Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Japan. ogawah@kumamoto-u.ac.jp
Suefuji
H
H
Takazoe
K
K
Soejima
H
H
Sakamoto
T
T
Miyamoto
S
S
Kaikita
K
K
Yoshimura
M
M
Kugiyama
K
K
Yasue
H
H
D000787:Angina Pectoris / Q000209:etiology; D006328:Cardiac Catheterization; D016022:Case-Control Studies; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000097:blood* / Q000145:classification* / Q000150:complications / Q000175:diagnosis; D005260:Female; D005342:Fibrinolysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D015849:Plasminogen Inactivators / Q000097:blood*; D011237:Predictive Value of Tests; D011379:Prognosis; D012008:Recurrence; D012720:Severity of Illness Index; D010959:Tissue Plasminogen Activator / Q000097:blood*
D015849:Plasminogen Inactivators; D010959:Tissue Plasminogen Activator