title: Patients with fibromyalgia have normal serum levels of hyaluronic acid.
abstract: OBJECTIVE
  To investigate the levels of hyaluronic acid (HA) in Danish patients with fibromyalgia (FM).
  
  
  METHODS
  Serum levels of HA were determined in 53 patients with established FM and 55 control samples using a radiometric assay. Values were correlated to clinical disease severity variables (duration of disease, tender point scales, visual analog scales).
  
  
  RESULTS
  There were no differences in HA levels between patients and controls. HA levels of all patients except one were within the reference ranges. There was no association between HA levels and clinical findings.
  
  
  CONCLUSIONS
  Patients with FM do not generally have increased serum levels of HA.
authors.affiliation: Department of Rheumatology, Frederiksberg Hospital, Copenhagen, Denmark. henning.bliddal@fh.hosp.dk
authors.forename: H
authors.initials: H
authors.lastname: Bliddal
authors.forename: H J
authors.initials: HJ
authors.lastname: Møller
authors.forename: M
authors.initials: M
authors.lastname: Schaadt
authors.forename: B
authors.initials: B
authors.lastname: Danneskiold-Samsøe
mesh_terms: D000375:Aging / Q000097:blood; D001172:Arthritis, Rheumatoid / Q000097:blood; D005260:Female; D005356:Fibromyalgia / Q000097:blood*; D006801:Humans; D006820:Hyaluronic Acid / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012016:Reference Values
chemical_list: D006820:Hyaluronic Acid