title: Bacterial Meningitis: Principles and Practical Aspects of Therapy.
abstract: Acute bacterial meningitis continues to be associated with significant morbidity and mortality. Recent research efforts to improve outcome for such patients have focused on antibiotic-cerebrospinal fluid interactions, factors influencing antibiotic selection, indications for cranial imaging, the role of anti-inflammatory agents, and the impact of antibiotic timing on outcome. In this article, I use an illustrative case to review timely data on these topics and provide guidelines for the empiric and pathogen-directed treatment of patients with acute bacterial meningitis.
authors.affiliation: Department of Internal Medicine, Section of Infectious Diseases, Waterbury Hospital Health Center, 64 Robbins Street, Waterbury, CT 06721, USA. saronin@wtbyhosp.chime.org
authors.initials: SI
authors.lastname: Aronin