Synthesis and application of planar-chiral phosphaferrocene-oxazolines, a new class of P,N-ligands
The synthesis of several phosphaferrocene-oxazolines, members of a new family of planar-chiral ligands, is described. These bidentate P, N-ligands are applied to enantioselective palladium-catalyzed allylic alkylations, for which it is shown that the planar-chirality of the phosphaferrocene, not the chirality of the oxazoline, determines the stereochemical outcome of the reaction.
Shintani
R
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
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MM
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GC