title: Biological effects and mechanism of action of farnesyl transferase inhibitors.
authors.affiliation: Department of Tumor Biology and Chemistry, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, USA.
authors.forename: H R
authors.initials: HR
authors.lastname: Ashar
authors.forename: L
authors.initials: L
authors.lastname: Armstrong
authors.forename: L J
authors.initials: LJ
authors.lastname: James
authors.forename: D M
authors.initials: DM
authors.lastname: Carr
authors.forename: K
authors.initials: K
authors.lastname: Gray
authors.forename: A
authors.initials: A
authors.lastname: Taveras
authors.forename: R J
authors.initials: RJ
authors.lastname: Doll
authors.forename: W R
authors.initials: WR
authors.lastname: Bishop
authors.forename: P T
authors.initials: PT
authors.lastname: Kirschmeier
mesh_terms: D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors*; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002453:Cell Cycle / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D016159:Tumor Suppressor Protein p53 / Q000502:physiology
chemical_list: D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D016159:Tumor Suppressor Protein p53; D019883:Alkyl and Aryl Transferases; C064911:p21(ras) farnesyl-protein transferase