Receptor binding and agonist efficacy: new insights from mutants of the thrombin protease-activated receptor-1 (PAR-1).
Hollenberg
M D
MD
Department of Pharmacology and Therapeutics and Department of Medicine, University of Calgary, Faculty of Medicine, Calgary, Alberta, Canada. mhollenb@ucalgary.ca
D006801:Humans; D008024:Ligands; D009154:Mutation; D010446:Peptide Fragments / Q000494:pharmacology; D044463:Receptor, PAR-1; D018179:Receptors, Thrombin / Q000819:agonists / Q000235:genetics / Q000378:metabolism*; D013917:Thrombin / Q000378:metabolism*
D008024:Ligands; D010446:Peptide Fragments; D044463:Receptor, PAR-1; D018179:Receptors, Thrombin; D013917:Thrombin