Comparison of a 60- versus 90-minute determination of ST-segment resolution after thrombolytic therapy for acute myocardial infarction. In TIME-II Investigators. Intravenous nPA for Treatment of Infarcting Myocardium Early-II.
Determination of ST-segment resolution 60 minutes after the administration of thrombolytic therapy allows accurate risk stratification for mortality and congestive heart failure. Patients with complete ST resolution at 60 minutes tended to be at lower risk for 30-day mortality than patients with complete ST resolution at 90 minutes.
de Lemos
J A
JA
Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Antman
E M
EM
Giugliano
R P
RP
Morrow
D A
DA
McCabe
C H
CH
Cutler
S S
SS
Charlesworth
A
A
Schröder
R
R
Braunwald
E
E
D001241:Aspirin / Q000627:therapeutic use; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D004562:Electrocardiography / Q000187:drug effects*; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D005500:Follow-Up Studies; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy / Q000503:physiopathology*; D016017:Odds Ratio; D010960:Plasminogen Activators / Q000627:therapeutic use*; D011379:Prognosis; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
D005343:Fibrinolytic Agents; C081981:lanoteplase; D006493:Heparin; D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator; D001241:Aspirin