title: Chronic eyelid lymphedema and acne rosacea. Report of two cases.
abstract: OBJECTIVE
  The authors describe the clinical findings and surgical treatment of two patients affected by chronic eyelid lymphedema associated with facial acne rosacea.
  
  
  METHODS
  Two interventional case reports. METHODS AND INTERVENTION: The clinical diagnosis of acne rosacea was based on the physical examination and confirmed by the histopathologic findings obtained from biopsy of the involved tissue. Surgical treatment was required to address the disfiguring chronic eyelid lymphedema and to correct the resultant mechanical lower eyelid ectropion in both patients.
  
  
  RESULTS
  Surgical debulking of the affected soft tissue resulted in very satisfactory cosmetic and functional improvement in both patients.
  
  
  CONCLUSIONS
  To our knowledge, this is the first series of cases of chronic eyelid lymphedema secondary to acne rosacea reported in the ophthalmic literature. Six similar cases have been described previously in the dermatologic literature; all of which had been treated medically without satisfactory results. Surgical debulking of the involved eyelids should be considered in patients affected by persistent symptomatic rosacea lymphedema.
authors.affiliation: Ophthalmology Clinic, S. Martino Hospital, University of Genova School of Medicine, Genova, Italy.
authors.forename: F P
authors.initials: FP
authors.lastname: Bernardini
authors.forename: R C
authors.initials: RC
authors.lastname: Kersten
authors.forename: L M
authors.initials: LM
authors.lastname: Khouri
authors.forename: M
authors.initials: M
authors.lastname: Moin
authors.forename: D R
authors.initials: DR
authors.lastname: Kulwin
authors.forename: D F
authors.initials: DF
authors.lastname: Mutasim
mesh_terms: D000368:Aged; D002908:Chronic Disease; D005141:Eyelid Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008209:Lymphedema / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D012393:Rosacea / Q000150:complications*