title: Recreational use of aminorex and pulmonary hypertension.
abstract: Pulmonary hypertension has been associated with ingestion of the appetite suppressant aminorex. A similar compound, 4-methyl-aminorex (street names, "U-4-E-uh" [pronounced euphoria] or "ice"), is a "designer" drug with central stimulant activity. This drug was discovered on the property of three individuals with diagnoses of pulmonary hypertension. The association between "recreational" aminorex manufacture and ingestion and the development of pulmonary hypertension is described.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: S P
authors.initials: SP
authors.lastname: Gaine
authors.forename: L J
authors.initials: LJ
authors.lastname: Rubin
authors.forename: J J
authors.initials: JJ
authors.lastname: Kmetzo
authors.forename: H I
authors.initials: HI
authors.lastname: Palevsky
authors.forename: T A
authors.initials: TA
authors.lastname: Traill
mesh_terms: D000328:Adult; D000635:Aminorex / Q000009:adverse effects*; D001067:Appetite Depressants / Q000009:adverse effects*; D000697:Central Nervous System Stimulants / Q000009:adverse effects; D015198:Designer Drugs; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000139:chemically induced*; D013287:Illicit Drugs / Q000009:adverse effects*; D008297:Male; D010080:Oxazoles / Q000009:adverse effects*; D019966:Substance-Related Disorders
chemical_list: D001067:Appetite Depressants; D000697:Central Nervous System Stimulants; D015198:Designer Drugs; D013287:Illicit Drugs; D010080:Oxazoles; D000635:Aminorex; C000081:4-methylaminorex