Adult Still's disease as a paraneoplastic manifestation of breast cancer.
We treated a patient who developed symptoms and findings indistinguishable from those of adult Still's disease as a manifestation of metastatic breast cancer 7 years after treatment for a stage 1 tumor. Although clinical features fulfilled diagnostic criteria for adult Still's disease, examination of a bone marrow biopsy specimen indicated that the apparent adult Still's disease was a paraneoplastic manifestation associated with diffuse marrow infiltration by breast cancer. The fever and polyarthralgia resolved with administration of prednisolone, and antiestrogen therapy with tamoxifen citrate was also started.
Neishi
J
J
The Third Department of Internal Medicine, Gunma University School of Medicine, Maebashi, Japan.
Tsukada
Y
Y
Maehara
T
T
Ueki
K
K
Maezawa
A
A
Nojima
Y
Y
D001943:Breast Neoplasms / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000209:etiology; D016706:Still's Disease, Adult-Onset / Q000175:diagnosis* / Q000209:etiology