Determination of constant rates of adsorption of ligand on DNA: analysis of correlation functions.
Correlation functions and spectral density of the number of molecules of ligand bound to DNA are calculated theoretically. Kinetics of rates of formation and decomposition of the complex are determined by calculating the dependence of correlation function on concentration of ligand in solution. The analysis of spectral density allows to distinguish "fast" and "slow" adsorption of ligands on macromolecule.
Arakelyan
V
V
Yerevan Physics Institute, Armenia.
Babayan
Y
Y
Potikyan
G
G
D000327:Adsorption; D004247:DNA / Q000737:chemistry*; D007700:Kinetics; D008024:Ligands; D008956:Models, Chemical; D008962:Models, Theoretical; D011485:Protein Binding
D008024:Ligands; D004247:DNA