title: [Evaluation of a new sequence of magnetic resonance cholangio-pancreatography in thick cut and one shot acquisition].
abstract: OBJECTIVE
  To assess the accuracy and reproducibility of a new magnetic resonance cholangiopancreatography sequence (MRCP), using long echo time and "single shot" acquisition (providing high-contrast thick slices: 20 mm or more), in the morphological analysis of the biliary tree and pancreatic ducts.
  
  
  METHODS
  Fifty four patients with biliary and/or pancreatic disease were investigated with MRCP "single shot" thick slices. Biliary ducts were explored with MRCP "single shot", coronal and oblique coronal 20 mm thick slices on a 256 x 256 matrix. Natives pictures were reviewed by three independent radiologists, from three different institutions. MRCP results were compared with reference examinations in 54 cases (direct biligraphy methods: 54, CT scan: 11, endoscopic ultrasonography: 6, surgery: 6).
  
  
  RESULTS
  For detection of bile duct dilatation, the agreement of MRCP "single shot" thick slices was more than 96% (Kappa > 0.92) and the inter-observer agreement was excellent (Kappa=0.92). For detection of biliary tree and/or pancreatic duct obstruction, MRCP "single shot" thick slice sensitivity was above 89% and specificity was 75%. The malignant nature of the lesions was determined with a sensitivity of 100% and a specificity of 92%. MRCP "single shot" thick slices could not differentiate pancreatic carcinomas from distal main bile duct cholangiocarcinomas. MRCP "single shot" thick slices did not detect small stones ( 3 mm) of the common bile duct.
  
  
  CONCLUSIONS
  The excellent sensitivity, specificity and inter-observer agreement of MRCP "single shot" thick slices can be used to limit invasive imaging methods in the diagnosis of extrahepatic cholestasis.
authors.affiliation: Service d'Hépato-Gastroentérologie, CHU Nancy.
authors.forename: J L
authors.initials: JL
authors.lastname: Mougenel
authors.forename: H
authors.initials: H
authors.lastname: Hudziak
authors.forename: O
authors.initials: O
authors.lastname: Ernst
authors.forename: B
authors.initials: B
authors.lastname: Dupas
authors.forename: F
authors.initials: F
authors.lastname: Lefevre
authors.forename: H
authors.initials: H
authors.lastname: Barraud
authors.forename: J
authors.initials: J
authors.lastname: Watelet
authors.forename: O
authors.initials: O
authors.lastname: Cezard
authors.forename: D
authors.initials: D
authors.lastname: Regent
authors.forename: M A
authors.initials: MA
authors.lastname: Bigard
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001650:Bile Duct Neoplasms / Q000175:diagnosis; D001652:Bile Ducts / Q000473:pathology*; D001653:Bile Ducts, Intrahepatic / Q000473:pathology; D001660:Biliary Tract Diseases / Q000175:diagnosis / Q000473:pathology; D018281:Cholangiocarcinoma / Q000175:diagnosis; D002758:Cholangiography; D003937:Diagnosis, Differential; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010182:Pancreatic Diseases / Q000175:diagnosis / Q000473:pathology; D010183:Pancreatic Ducts / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000175:diagnosis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity