Antitussive effect of Asparagus racemosus root against sulfur dioxide-induced cough in mice.
The methanol extract of Asparagus racemosus root (200 and 400 mg/kg, p.o.) showed significant antitussive activity on sulfur dioxide-induced cough in mice, the cough inhibition (40.0 and 58.5%, respectively) being comparable to that of 10-20 mg/kg of codeine phosphate (36.0 and 55.4%, respectively).
Mandal
S C
SC
Division of Pharmacognosy, Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta-700 032, India. madhabi@giasc101.vsnl.net.in
Kumar C K
A
A
Mohana Lakshmi
S
S
Sinha
S
S
Murugesan
T
T
Saha
B P
BP
Pal
M
M
D000818:Animals; D000996:Antitussive Agents / Q000627:therapeutic use*; D003371:Cough / Q000139:chemically induced / Q000188:drug therapy*; D005260:Female; D019668:Liliaceae; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000627:therapeutic use; D018517:Plant Roots; D013458:Sulfur Dioxide
D000996:Antitussive Agents; D010936:Plant Extracts; D013458:Sulfur Dioxide