title: New butenolides from two marine streptomycetes.
abstract: Chemical examination of two marine Streptomycetes has resulted in the isolation of four new butenolides, namely 4, 10-dihydroxy-10-methyl-dodec-2-en-1,4-olide (1), two diastereomeric 4,11-dihydroxy-10-methyl-dodec-2-en-1,4-olides (2/3), and 4-hydroxy-10-methyl-11-oxo-dodec-2-en-1,4-olide (4). The structures were identified by interpretation of the 2D NMR and mass spectral data.
authors.affiliation: Department of Organic Chemistry, University of Goettingen, Tammannstrasse 2, D-37077 Goettingen, Germany.
authors.forename: V J
authors.initials: VJ
authors.lastname: Mukku
authors.forename: M
authors.initials: M
authors.lastname: Speitling
authors.forename: H
authors.initials: H
authors.lastname: Laatsch
authors.forename: E
authors.initials: E
authors.lastname: Helmke
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002942:Circular Dichroism; D005285:Fermentation; D005663:Furans / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D013172:Spores, Fungal / Q000187:drug effects; D013306:Streptomycetaceae / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D005663:Furans; C004511:butenolide; D015107:4-Butyrolactone