An alternative base-pairing of catechol-bearing nucleosides by borate formation.
A chelator-type beta-C-nucleoside having a catechol ligand as the nucleobase was found to form a stable 2:1 complex with trimethyl borate, which was characterized by 1H-NMR and electrospray ionization time-of-flight (ESI-TOF) mass spectroscopies. Both phosphoramidite and phosphotriester derivatives of this nucleoside were also prepared as synthetic precursors for DNA oligomer syntheses.
Cao
H
H
The Graduate University for Advanced Studies, Myodaiji, Okazaki, Japan.
Tanaka
K
K
Shionoya
M
M
D020029:Base Pairing; D001881:Borates / Q000737:chemistry*; D002396:Catechols / Q000737:chemistry*; D002614:Chelating Agents; D009682:Magnetic Resonance Spectroscopy; D009705:Nucleosides / Q000737:chemistry*; D009841:Oligonucleotides / Q000138:chemical synthesis / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
D001881:Borates; D002396:Catechols; D002614:Chelating Agents; D009705:Nucleosides; D009841:Oligonucleotides