title: Periodontal medicine: a new paradigm.
abstract: Recent evidence indicates that we need to change how we think about the etiology and pathogenesis of periodontal disease. Although bacteria are a necessary factor in the equation, the reaction of the host's immuno-inflammatory system is responsible for most of the destruction found in periodontal disease. Thus, it makes sense that a number of environmental and acquired factors may modify a patient's risk of developing periodontal disease. This paper reviews the scientific evidence for a number of these risk factors including age, genetics, smoking, diabetes mellitus, stress and osteoporosis.
authors.affiliation: Division of Periodontics, Faculty of Dentistry, Dalhousie University. debora.matthews@dal.ca
authors.forename: D C
authors.initials: DC
authors.lastname: Matthews
mesh_terms: D000367:Age Factors; D002318:Cardiovascular Diseases / Q000150:complications; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D007375:Interleukin-1 / Q000235:genetics; D010518:Periodontitis / Q000453:epidemiology* / Q000209:etiology* / Q000235:genetics; D011247:Pregnancy; D011248:Pregnancy Complications; D012307:Risk Factors; D012907:Smoking; D013315:Stress, Psychological / Q000150:complications
chemical_list: D007375:Interleukin-1