title: Alteration of sonographic texture of the endometrium in post-menopausal bleeding. A guide to further management.
abstract: BACKGROUND
  The purpose of this study was to assess the utility of transvaginal ultrasonography in the evaluation of endometrial morphology in addition to the standard criterion of endometrial thickness for selecting patients for endometrial sampling.
  
  
  METHODS
  Two hundred and seven consecutive cases of postmenopausal bleeding were evaluated by transvaginal ultrasound. Endometrial thickness was measured as the maximum anteroposterior thickness of the endometrium including both the anterior and posterior layers, in the sagittal long axis view. The morphology of the endometrium was studied and categorized as homogeneous, focally increased echogenecity, diffusely increased echogenecity or diffusely inhomogeneous. Patients were followed up for clinical course and endometrial histopathology.
  
  
  RESULTS
  Textural inhomogeneity was observed in all the three cases of endometrial cancers with endometrial thickness of less than 6 mm, and, in ten out of 11 cases of a more than 6 mm thick endometrium. On the other hand the endometrial texture was homogeneous in all cases of endometrial atrophy/tissue inadequate for diagnosis, with thickness of less than 6 mm.
  
  
  CONCLUSIONS
  This study adds the dimension of abnormal echogenecity of the endometrium to the currently followed criterion of endometrial thickness with a view to enhance accuracy, both for a better prediction of atrophy and a higher prediction for endometrial cancer. Expectant management can be offered to patients with a homogeneous endometrium which is 6 mm thick or less. Aggressive evaluation for a malignancy must be made if there is a focal increased echogenecity or a diffuse increased echogenecity even in a thin endometrium.
authors.affiliation: Department of Radiology, Faculty of Medicine, Kuwait University.
authors.forename: M
authors.initials: M
authors.lastname: Sheikh
authors.forename: S
authors.initials: S
authors.lastname: Sawhney
authors.forename: A
authors.initials: A
authors.lastname: Khurana
authors.forename: M
authors.initials: M
authors.lastname: Al-Yatama
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004717:Endometrium / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause / Q000502:physiology; D012680:Sensitivity and Specificity; D014463:Ultrasonography / Q000379:methods*; D014592:Uterine Hemorrhage / Q000000981:diagnostic imaging* / Q000209:etiology