Friulimicins: novel lipopeptide antibiotics with peptidoglycan synthesis inhibiting activity from Actinoplanes friuliensis sp. nov. I. Taxonomic studies of the producing microorganism and fermentation.
A strain that produces new lipopeptide antibiotics is a new species of the genus Actinoplanes for which we propose the name Actinoplanes friuliensis (type strain: HAG 010964). The strain is an actinoplanete actinomycete having cell wall II composition and forming sporangia. Comparisons with Actinoplanes spp. which have similarities with our isolate, including fatty acid analysis, showed that the isolate belongs to a new species. Taxonomic studies and fermentation are presented.
Aretz
W
W
HMR Deutschland GmbH, Frankfurt am Main, Germany.
Meiwes
J
J
Seibert
G
G
Vobis
G
G
Wink
J
J
D000192:Actinomycetales / Q000145:classification* / Q000378:metabolism* / Q000502:physiology; D000900:Anti-Bacterial Agents / Q000378:metabolism / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005227:Fatty Acids / Q000378:metabolism; D005285:Fermentation; D008826:Microbial Sensitivity Tests; D010457:Peptidoglycan / Q000096:biosynthesis / Q000187:drug effects; D011500:Protein Synthesis Inhibitors / Q000378:metabolism / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D005227:Fatty Acids; D010457:Peptidoglycan; D011500:Protein Synthesis Inhibitors