Endocrine/paracrine control of pituitary cell proliferation and its involvement in pituitary tumorigenesis.
The paper concisely reviews the data on the humoral factors which regulate the anterior pituitary cell proliferation in endocrine and/or paracrine manner. Their relevance for pituitary tumorigenesis is also discussed. The role of estrogens, growth factors, neuropeptides, dopamine, interleukins and angiotensins is presented.
Pawlikowski
M
M
Department of Experimental Endocrinology and Hormone Diagnostics, Medical University of Lodz, Poland.
D000809:Angiotensins / Q000502:physiology; D002455:Cell Division / Q000502:physiology; D004967:Estrogens / Q000502:physiology; D006133:Growth Substances / Q000502:physiology; D006801:Humans; D007378:Interleukins / Q000502:physiology; D009479:Neuropeptides / Q000502:physiology; D018377:Neurotransmitter Agents / Q000502:physiology; D010903:Pituitary Gland, Anterior / Q000166:cytology* / Q000502:physiology*; D010907:Pituitary Hormones / Q000502:physiology*; D010911:Pituitary Neoplasms / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology*
D000809:Angiotensins; D004967:Estrogens; D006133:Growth Substances; D007378:Interleukins; D009479:Neuropeptides; D018377:Neurotransmitter Agents; D010907:Pituitary Hormones