[Dydrogesterone (Duphaston) in the prevention of risk of ultrasound guided amniocentesis].
Oral administration of 20 mg per day Dydrogesterone was recommended in 28 pregnancies as a prevention of risks due to ultrasound guided amniocentesis. Reduction rate (3.6% vs. 5.0%) of uterine cramping and/or uterine contraction wave, observed in US were noticed comparing to the control (n = 40). No spontaneous abortion was noticed in both groups during two weeks follow up. Amniotic fluid leakage was noticed in 2.5% of control comparing to none in the Dydrogesterone group.
Korczyński
J
J
II Kliniki Ginekologii Instytutu Ginekologii i Połoznictwa Akademii Medycznej w Lodzi.
D000022:Abortion, Spontaneous / Q000175:diagnosis / Q000517:prevention & control*; D000284:Administration, Oral; D000649:Amniocentesis / Q000379:methods*; D004394:Dydrogesterone / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D011247:Pregnancy; D045167:Progesterone Congeners / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D012307:Risk Factors; D014463:Ultrasonography; D014590:Uterine Contraction / Q000187:drug effects*; D014599:Uterus / Q000000981:diagnostic imaging*
D045167:Progesterone Congeners; D004394:Dydrogesterone