The therapeutic value of somatostatin and its analogues.
In this review we discuss the physiological effects of somatostatin, which are mediated by specific receptor subtypes on different tissues. These observations have suggested new therapeutic possibilities for the use of the synthetic somatostatin analogues in the treatment of acromegaly as well as a number of other endocrine and non-endocrine disorders.
Farooqi
S
S
Department of Medicine, Addenbrooke's Hospital, Cambridge, UK.
Bevan
J S
JS
Sheppard
M C
MC
Wass
J A
JA
D000172:Acromegaly / Q000188:drug therapy*; D006727:Hormone Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D010911:Pituitary Neoplasms / Q000188:drug therapy; D013004:Somatostatin / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use*
D006727:Hormone Antagonists; D013004:Somatostatin