title: Impeller design for a miniaturized centrifugal blood pump.
abstract: The impeller design for a miniature centrifugal blood pump is an important consideration since the small diameter impeller requires higher rotational speed, which may cause more blood trauma compared to the larger diameter impeller. Three different impeller vanes (straight vanes with a height of 4 mm and 8 mm, and 8 mm curved vanes) of which the diameter was 35 mm were subjected to hydraulic performance and hemolysis tests in the same pump housing. Both straight vane impellers attained left ventricular assist condition (5 L/min against 100 mm Hg) at 2,900 rpm while the curved vane required 3,280 rpm. There was no significant hemolysis difference between the tall and short vanes. The curved impeller vanes did not exhibit sufficient hydraulic performance when compared to the straight vanes. The straight vane impellers, even with different heights, were incorporated into the same pump housings, and the vane heights did not drastically change the hydraulic performance or hemolysis.
authors.affiliation: Baylor College of Medicine, Department of Surgery, Houston, Texas 77030, USA. ttakano@bcm.tmc.edu
authors.forename: T
authors.initials: T
authors.lastname: Takano
authors.forename: S
authors.initials: S
authors.lastname: Schulte-Eistrup
authors.forename: M
authors.initials: M
authors.lastname: Yoshikawa
authors.forename: K
authors.initials: K
authors.lastname: Nakata
authors.forename: S
authors.initials: S
authors.lastname: Kawahito
authors.forename: T
authors.initials: T
authors.lastname: Maeda
authors.forename: K
authors.initials: K
authors.lastname: Nonaka
authors.forename: J
authors.initials: J
authors.lastname: Linneweber
authors.forename: J
authors.initials: J
authors.lastname: Glueck
authors.forename: A
authors.initials: A
authors.lastname: Fujisawa
authors.forename: K
authors.initials: K
authors.lastname: Makinouchi
authors.forename: M
authors.initials: M
authors.lastname: Yokokawa
authors.forename: Y
authors.initials: Y
authors.lastname: Nosé
mesh_terms: D004867:Equipment Design; D006353:Heart-Assist Devices; D006801:Humans; D008904:Miniaturization