title: Experimental infection model for Taenia solium cysticercosis in swine. Cysticercosis Working Group in Peru.
abstract: A novel method for infecting pigs with Taenia solium using an intramuscular innoculum of oncospheres was investigated in a series of five experiments in 18 animals. The model is simple to perform, requires a minimal number of oncospheres, permits multiple infections per animal, and decreases the variation inherent in oral infection models. This intramuscular oncosphere assay (IMOA) may provide a valuable tool to evaluate therapeutic agents or potential vaccines for cysticercosis.
authors.affiliation: Department of Pathology and Department of Microbiology, Universidad Peruana Cayetano Heredia, PO Box 5045, Lima, Peru.
authors.forename: M
authors.initials: M
authors.lastname: Verástegui
authors.forename: A
authors.initials: A
authors.lastname: González
authors.forename: R H
authors.initials: RH
authors.lastname: Gilman
authors.forename: C
authors.initials: C
authors.lastname: Gavidia
authors.forename: N
authors.initials: N
authors.lastname: Falcón
authors.forename: T
authors.initials: T
authors.lastname: Bernal
authors.forename: H H
authors.initials: HH
authors.lastname: Garcia
mesh_terms: D000284:Administration, Oral; D000818:Animals; D003551:Cysticercosis / Q000469:parasitology / Q000662:veterinary*; D003552:Cysticercus / Q000472:pathogenicity*; D004195:Disease Models, Animal; D006651:Histocytochemistry; D007273:Injections, Intramuscular / Q000662:veterinary; D007274:Injections, Intraperitoneal / Q000662:veterinary; D007275:Injections, Intravenous / Q000662:veterinary; D013552:Swine; D013553:Swine Diseases / Q000469:parasitology*