title: Physical injury as a provoking factor in three patients with scleroderma.
abstract: A 51-year-old female developed linear-like scleroderma in the left thigh following a linear wound caused by a car accident. 27 years later she also developed a typical diffuse cutaneous systemic sclerosis with extensive skin involvement and bibasilar pulmonary fibrosis. The second case is a 39-year-old female who had a history of Raynaud's phenomenon since early childhood. She developed a morphea following a burning injury of the left thigh. 17 years later she also developed a typical limited cutaneous systemic sclerosis with sclerodactyly, skin ulcers and subcutaneous calcinosis. The third case is a 43-year-old female who developed a typical morphea of the right elbow around the site of a previous local corticosteroid injection. The two remarkable points of these 3 cases are the possible role of physical injury in the provocation of localized scleroderma and in the first 2 cases the unusual later development of a systemic form of scleroderma.
authors.affiliation: 2nd Department of Internal Medicine, University Medical School of Pécs, Hungary.
authors.forename: A
authors.initials: A
authors.lastname: Komócsi
authors.forename: E
authors.initials: E
authors.lastname: Tóvári
authors.forename: J
authors.initials: J
authors.lastname: Kovács
authors.forename: L
authors.initials: L
authors.lastname: Czirják
mesh_terms: D000328:Adult; D002056:Burns / Q000150:complications; D005260:Female; D006801:Humans; D007267:Injections / Q000009:adverse effects; D008875:Middle Aged; D012594:Scleroderma, Localized / Q000209:etiology* / Q000473:pathology; D012595:Scleroderma, Systemic / Q000209:etiology* / Q000473:pathology; D013848:Thigh / Q000293:injuries; D014947:Wounds and Injuries / Q000150:complications*