title: Trauma in cirrhotics: survival and hospital sequelae in patients requiring abdominal exploration.
abstract: Hepatic cirrhosis significantly increases the mortality and morbidity of elective surgery; therefore we hypothesized that cirrhosis would adversely impact outcome after abdominal trauma. We used the trauma registry to identify 17 patients with cirrhosis who sustained trauma injuries requiring emergent exploratory laparotomy. Patients were characterized with respect to age, sex, hospital days, intensive care unit days, and trauma scores. A control group (n = 73) was constructed from the registry by matching age, sex, Injury Severity Score (ISS) and Abbreviated Injury score. Mortality rates were compared by Fisher's exact test and age, ISS, Revised Trauma Score 2, and hospital and intensive care unit days were compared by Student's t test. Despite similar ISS between cirrhotic patients and controls, patients with cirrhosis had a fourfold increase in mortality (mortality odds ratio = 7.2; 95% confidence interval = 2.2-24.0). Cirrhotic trauma patients had a complication rate of 71 per cent and a mortality of 44 per cent. We conclude that cirrhosis is a major independent risk factor for mortality in trauma patients with injuries that require emergent abdominal surgery.
authors.affiliation: Department of Surgery, Hennepin County Medical Center, University of Minnesota, Minneapolis, 55415, USA.
authors.forename: K
authors.initials: K
authors.lastname: Wahlstrom
authors.forename: A L
authors.initials: AL
authors.lastname: Ney
authors.forename: S
authors.initials: S
authors.lastname: Jacobson
authors.forename: M D
authors.initials: MD
authors.lastname: Odland
authors.forename: J M
authors.initials: JM
authors.lastname: Van Camp
authors.forename: J L
authors.initials: JL
authors.lastname: Rodriguez
authors.forename: M A
authors.initials: MA
authors.lastname: West
mesh_terms: D018806:APACHE; D000007:Abdominal Injuries / Q000150:complications* / Q000401:mortality* / Q000601:surgery; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007902:Length of Stay; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D015996:Survival Rate; D016896:Treatment Outcome