title: Adverse reaction to dental local anaesthetic injection--'allergy' is not the cause.
abstract: OBJECTIVE
  To investigate patients considered to have experienced allergic reactions to local anaesthetics administered for dental treatment.
  
  
  METHODS
  Dental facility within a general hospital.
  
  
  METHODS
  Skin and intra-oral challenge tests.
  
  
  RESULTS
  No patients were found to be allergic to lignocaine or prilocaine. The most likely causes of the adverse reactions were found to be psychogenic.
  
  
  CONCLUSIONS
  Although allergy to lignocaine (and the other amide anaesthetic agents used in dentistry) is known to be extremely rare, it continues to be suggested as a cause when adverse reactions to dental injections occur. Psychogenic reactions are the main causes of untoward events, and some can be alarming. A smaller proportion of adverse responses can be attributed to (avoidable) intravascular injections. Adverse reactions can be reduced if injections are administered carefully.
authors.affiliation: GKT Dental Institute, King's College Hospital, London.
authors.forename: J P
authors.initials: JP
authors.lastname: Rood
mesh_terms: D000766:Anesthesia, Dental / Q000009:adverse effects* / Q000523:psychology*; D000779:Anesthetics, Local / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D006801:Humans; D007159:Immunologic Tests; D007267:Injections / Q000009:adverse effects; D008012:Lidocaine / Q000009:adverse effects; D008297:Male; D011318:Prilocaine / Q000009:adverse effects; D011602:Psychophysiologic Disorders / Q000175:diagnosis*; D013575:Syncope / Q000209:etiology
chemical_list: D000779:Anesthetics, Local; D011318:Prilocaine; D008012:Lidocaine