Mitosis: shutting the door behind when you leave.
Yeast cells must segregate sister chromosomes to the opposite sides of the bud neck during mitosis. A pathway has been identified, involving a small GTPase, which prevents the onset of cytokinesis until one of the spindle poles has migrated into the bud.
Li
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Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA. Rli@hms.harvard.edu
D002455:Cell Division; D002875:Chromosomes / Q000378:metabolism*; D005656:Fungal Proteins / Q000378:metabolism; D008870:Microtubules / Q000378:metabolism; D008938:Mitosis; D008954:Models, Biological; D020559:Monomeric GTP-Binding Proteins / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000502:physiology*; D029701:Saccharomyces cerevisiae Proteins; D008941:Spindle Apparatus / Q000378:metabolism*
D005656:Fungal Proteins; D029701:Saccharomyces cerevisiae Proteins; C089965:TEM1 protein, S cerevisiae; D020559:Monomeric GTP-Binding Proteins