Alveolar soft-part sarcoma of the cheek: report of a case with a review of the literature.
An alveolar soft-part sarcoma (ASPS) occurring in the cheek is described, with a review of the literature. The subject was a 25-year-old woman who presented with a large swelling in the left cheek. The lesion, initially diagnosed as a benign tumor on radiographic and computed tomographic examinations, was surgically excised. Histopathological examination of the mass revealed a nest-like or organoid cellular arrangement as confirmed by three-dimensional computer graphic reconstruction. The cytoplasm of the large polygonal tumor cells contained abundant diastase-resistant, PAS-positive inclusions, ultrastructurally confirmed to be crystalloid materials. The tumor cells were immunoreactive for anti-myoglobin, sarcomeric actin, and neuron-specific enolase antibodies, suggesting a myogenic origin.
Kimi
K
K
Department of Oral Pathology, Tohoku University School of Dentistry, Sendai, Japan.
Onodera
K
K
Kumamoto
H
H
Ichinohasama
R
R
Echigo
S
S
Ooya
K
K
D000328:Adult; D002610:Cheek; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D018234:Sarcoma, Alveolar Soft Part / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery