title: Current Concepts of Therapy for Otitis Media.
abstract: The therapy for acute otitis media is currently a topic in evolution. What was once a straightforward approach of matching middle ear pathogens to appropriate antibiotics has become a complex calculus that attempts to balance multiple terms such as spontaneous cure, emergence of resistance, pharmacokinetics-dynamics, antibiotic therapeutic efficacy, suppurative complications, and cost. This review highlights new developments in our understanding of this complex interaction of the issues surrounding a physician's decision to begin antibiotic therapy for acute otitis media.
authors.affiliation: Pediatric Infectious Diseases, Georgetown University Children's Medical Center, 3800 Reservoir Road, NW, 2-PHC, Washington, DC 20007-2197, USA.
authors.initials: RL
authors.lastname: Wientzen
authors.initials: C
authors.lastname: Barbey-Morel