Concise asymmetric synthesis of beta-hydroxy alpha-amino acids using the sulfinimine-mediated asymmetric Strecker synthesis: phenylserine and beta-hydroxyleucine.
Davis
F A
FA
Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA. fdavis@astro.ocis.temple.edu
Srirajan
V
V
Fanelli
D L
DL
Portonovo
P
P
D000447:Aldehydes / Q000737:chemistry; D007097:Imines / Q000737:chemistry; D007202:Indicators and Reagents; D007930:Leucine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D013237:Stereoisomerism
D000447:Aldehydes; D007097:Imines; D007202:Indicators and Reagents; C013048:beta-hydroxyphenylalanine; D010649:Phenylalanine; C024584:beta-hydroxyleucine; D007930:Leucine