Recent advances in breast cancer biology.
Approximately 1 in 10 US women will be diagnosed with breast cancer in her lifetime. With such a high incidence, breast cancer is a serious health concern for all American women. Within the past year, clues about the function of genes associated with breast cancer have been garnered, and novel genes that may contribute to breast tumorigenesis have been discovered. In addition, unique animal models and improvements in gene expression profiling technology have given researchers new tools to address previously unanswerable questions about this disease.
Unger
M A
MA
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA.
Weber
B L
BL
D000818:Animals; D024682:BRCA2 Protein; D001943:Breast Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000473:pathology*; D004195:Disease Models, Animal; D005260:Female; D019398:Genes, BRCA1 / Q000235:genetics* / Q000502:physiology; D006801:Humans; D009363:Neoplasm Proteins / Q000235:genetics* / Q000502:physiology; D014157:Transcription Factors / Q000235:genetics* / Q000502:physiology; D014158:Transcription, Genetic
D024682:BRCA2 Protein; D009363:Neoplasm Proteins; D014157:Transcription Factors