In vitro antibiotic susceptibility of Bacteroides fragilis strains isolated from excised appendix of patients with phlegmonous or gangrenous appendicitis.
Out of 34 studied after-appendectomy tissues of adult and child patients 86 different strains of anaerobes were isolated. The antibiotic susceptibility of 30 isolated B. fragilis strains was tested using E tests. All studied strains were sensitive to imipenem, clindamycin and penicillin/tazobactam. Sensitivity to penicillin and cefoxitin was variable among these strains. One strain resistant to metronidazole (MIC--256 mg/L) and 3 strains with increased MIC to metronidazole were detected. Most of isolated strains were beta-lactamase producers.
Wójcik-Stojek
B
B
Institute of Microbiology, Collegium Medicum Jagiellonian, University of Cracow, Poland.
Bulanda
M
M
Martirosian
G
G
Heczko
P
P
Meisel-Mikołajczyk
F
F
D000328:Adult; D001064:Appendicitis / Q000382:microbiology* / Q000601:surgery; D001065:Appendix / Q000382:microbiology*; D001441:Bacteroides fragilis / Q000187:drug effects* / Q000302:isolation & purification; D002648:Child; D004352:Drug Resistance, Microbial; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests
D008795:Metronidazole