title: ICE bioassay. Isolating in vivo complexes of enzyme to DNA.
authors.affiliation: Department of Molecular Genetics, Ohio State University, Columbus, USA.
authors.forename: D
authors.initials: D
authors.lastname: Subramanian
authors.forename: C S
authors.initials: CS
authors.lastname: Furbee
authors.forename: M T
authors.initials: MT
authors.lastname: Muller
mesh_terms: D002499:Centrifugation, Density Gradient; D002586:Cesium / Q000378:metabolism; D002712:Chlorides / Q000378:metabolism; D004247:DNA / Q000378:metabolism*; D004264:DNA Topoisomerases, Type I / Q000032:analysis / Q000378:metabolism*; D004250:DNA Topoisomerases, Type II / Q000032:analysis / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000032:analysis / Q000037:antagonists & inhibitors / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D015151:Immunoblotting; D012521:Sarcosine / Q000031:analogs & derivatives / Q000494:pharmacology; D013713:Teniposide / Q000494:pharmacology; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; D019772:Topotecan / Q000494:pharmacology; D014407:Tumor Cells, Cultured
chemical_list: D002712:Chlorides; D004268:DNA-Binding Proteins; D004791:Enzyme Inhibitors; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; D002586:Cesium; C025231:sarkosyl; D019772:Topotecan; D004247:DNA; D013713:Teniposide; D004264:DNA Topoisomerases, Type I; D004250:DNA Topoisomerases, Type II; C028019:cesium chloride; D012521:Sarcosine