Disease outcome subsequent to primary and secondary urogenital infection with murine or human biovars of Chlamydia trachomatis.
A susceptible strain of mice infected intravaginally with the mouse pneumonitis biovar of Chlamydia trachomatis became infertile and sustained high rates of hydrosalpinx formation regardless of prior infection with a human serovar. Conversely, susceptible mice infected with human serovars remained fertile unless challenged with a homologous human serovar.
Ramsey
K H
KH
Microbiology Department, Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, Illinois 60515, USA. kramse@midwestern.edu
DeWolfe
J L
JL
Salyer
R D
RD
D000818:Animals; D002690:Chlamydia Infections / Q000150:complications* / Q000473:pathology; D002692:Chlamydia trachomatis / Q000145:classification; D004195:Disease Models, Animal; D005260:Female; D005831:Genital Diseases, Female / Q000150:complications*; D006367:HeLa Cells; D006801:Humans; D007247:Infertility, Female / Q000209:etiology*; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H