Smooth muscle tumor of the pleura. A case report and review of the literature.
Smooth muscle tumors of the serosal membranes are extremely rare and have received little attention in the literature. To the best of our knowledge, only 1 published series of 5 pleural smooth muscle neoplasms has been published to date. We describe a primary pleural neoplasm with smooth muscle differentiation documented by light microscopy, immunohistochemistry, and electron microscopy. This tumor originated in the parietal pleura in a 32-year-old white man and was diagnosed incidentally by chest radiography; the diagnosis was confirmed by magnetic resonance imaging and biopsy. Four years later, the tumor was noted to have increased in size and disseminated into the chest wall as a separate circumscribed mass located in the pectoral muscle. Both masses were resected and diagnosed as smooth muscle tumors. We conclude that smooth muscle tumor of the pleura is a well-defined entity with a low, but definite malignant potential; therefore, we recommend complete resection and long-term follow-up for all patients.
Proca
D M
DM
Department of Pathology, The Ohio State University Medical Center and Arthur G. James Cancer Hospital and Research Institute, Columbus 43210, USA.
Ross
P
P
Pratt
J
J
Frankel
W L
WL
D000199:Actins / Q000032:analysis; D000328:Adult; D000368:Aged; D003893:Desmin / Q000032:analysis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000737:chemistry; D018995:Myosin Heavy Chains / Q000032:analysis; D010997:Pleural Neoplasms / Q000378:metabolism / Q000473:pathology*; D018235:Smooth Muscle Tumor / Q000378:metabolism / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
D000199:Actins; D003893:Desmin; D014746:Vimentin; D018995:Myosin Heavy Chains