Neurobehavioral and neuropsychiatric symptoms in Alzheimer's disease: characteristics and treatment.
Neuropsychiatric symptoms are common in Alzheimer's disease. Personality changes, mood disturbance, and psychosis are frequently seen and may coexist in the same patient. Neuropsychiatric symptoms may signal the onset of disease and often fluctuate and recur. These symptoms are associated with a more rapid cognitive and functional decline that can lead to institutionalization. Cholinergic therapy, disease-modifying therapy, and psychotropic medications can improve these symptoms.
Chung
J A
JA
Department of Neurology, University of California Los Angeles, Los Angeles, California 90095-1769, USA.
Cummings
J L
JL
D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D018678:Cholinergic Agents / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D001523:Mental Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D009483:Neuropsychological Tests; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use
D018678:Cholinergic Agents; D011619:Psychotropic Drugs