title: Effects of left ventricular pacing on cardiac performance and on quality of life in patients with drug refractory heart failure.
abstract: We assessed the effects of left ventricular pacing on echocardiographic and clinical parameters in 13 consecutive patients with heart failure and bundle branch block by means of a controlled acute and medium-term evaluation. Left ventricular pacing induced a significant improvement in left ventricular ejection fraction, Minnesota Living with Heart Failure Questionnaire score, New York Heart Association class, and 6-minute walking test compared with sinus rhythm or right ventricular pacing.
authors.affiliation: Arrhythmologic Centers, Ospedali Riunti, Lavagna, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Lupi
authors.forename: M
authors.initials: M
authors.lastname: Brignole
authors.forename: D
authors.initials: D
authors.lastname: Oddone
authors.forename: R
authors.initials: R
authors.lastname: Bollini
authors.forename: C
authors.initials: C
authors.lastname: Menozzi
authors.forename: N
authors.initials: N
authors.lastname: Bottoni
mesh_terms: D000368:Aged; D002304:Cardiac Pacing, Artificial; D002316:Cardiotonic Agents / Q000627:therapeutic use*; D018592:Cross-Over Studies; D004311:Double-Blind Method; D004361:Drug Tolerance; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006333:Heart Failure / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D008297:Male; D011379:Prognosis; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016277:Ventricular Function, Left / Q000502:physiology*
chemical_list: D002316:Cardiotonic Agents