High-dose chemotherapy in poor-risk germ-cell tumors.
Testicular cancer is a highly curable cancer. However, 30% of patients are refractory to standard therapy and will need additional therapy. This article focuses on the use of high-dose chemotherapy in germ-cell tumors. High-dose chemotherapy use is discussed both in the refractory setting and as either first-salvage or first-line therapy. Various criteria for risk assessment are also discussed.
Srinivas
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Division of Medical Oncology, Veterans Affairs Medical Center, Palo Alto, California, USA.
D000970:Antineoplastic Agents / Q000008:administration & dosage; D018237:Germinoma / Q000188:drug therapy*; D006801:Humans; D008297:Male; D013736:Testicular Neoplasms / Q000188:drug therapy*
D000970:Antineoplastic Agents