Use of phage display and transition-state analogs to select enzyme variants with altered catalytic properties: glutathione transferase as an example.
Widersten
M
M
Department of Biochemistry, Uppsala University, Sweden.
Hansson
L O
LO
Tronstad
L
L
Mannervik
B
B
D001665:Binding Sites; D002384:Catalysis; D004798:Enzymes / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D014644:Genetic Variation; D005982:Glutathione Transferase / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D006801:Humans; D007202:Indicators and Reagents; D008024:Ligands; D008958:Models, Molecular; D016297:Mutagenesis, Site-Directed; D019151:Peptide Library; D017433:Protein Structure, Secondary; D021122:Protein Subunits; D011993:Recombinant Fusion Proteins / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism
D004798:Enzymes; D007202:Indicators and Reagents; D008024:Ligands; D019151:Peptide Library; D021122:Protein Subunits; D011993:Recombinant Fusion Proteins; D005982:Glutathione Transferase