Current status of food animal antidotes.
The availability of antidotes in veterinary medicine has been an issue for more than a decade. Antidotes are available for food animals through extralabel use, regulatory discretion, and compounding. There is little economic incentive for pharmaceutical companies to pursue approval of antidotes and other drug products that have a small market. In addition, human food safety concerns must be addressed when approving antidotes for use in food animals. This article provides a brief history of antidote availability, current mechanisms for procuring food animal antidotes, and availability of specific antidotes for use in food animals.
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Division of Surveillance, Food and Drug Administration, Rockville, Maryland, USA.
Keller
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D000822:Animal Husbandry; D000818:Animals; D000829:Animals, Domestic; D000931:Antidotes / Q000600:supply & distribution* / Q000627:therapeutic use; D003257:Consumer Product Safety / Q000331:legislation & jurisprudence*; D017277:Drug Approval; D005506:Food Contamination / Q000517:prevention & control; D006801:Humans; D014481:United States; D014486:United States Food and Drug Administration / Q000331:legislation & jurisprudence*; D014730:Veterinary Medicine
D000931:Antidotes