Adipose redistribution in human immunodeficiency virus-seropositive patients: association with CD4 response.
We have noted that human immunodeficiency virus (HIV)-seropositive patients who develop adipose redistribution (AR) while receiving combination antiretroviral therapy (ART) also tend to have a better response to ART, as indicated by the relative change in CD4 percent compared to those who don't develop AR on therapy. Whether the possible benefits of the improved CD4 response outweigh the metabolic and cosmetic problems associated with lipodystrophy is not known.
Wurtz
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R
Evanston Northwestern Healthcare and Northwestern University, Evanston, IL, USA. rwurtz@nwu.edu
Ceaser
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S
D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D018791:CD4 Lymphocyte Count; D004359:Drug Therapy, Combination; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000276:immunology*; D015497:HIV-1; D006801:Humans; D008060:Lipodystrophy / Q000209:etiology / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D018894:Reverse Transcriptase Inhibitors / Q000627:therapeutic use
D019380:Anti-HIV Agents; D018894:Reverse Transcriptase Inhibitors