Glucose and galactose absorption after ingestion of milk containing hydrolysed lactose in calves with diarrhoea.
Ten calves which had contracted acute diarrhoea caused by rotavirus, coronavirus and Cryptosporidium were used to test the hypothesis that feeding lactose-hydrolysed cow's milk instead of unprocessed cow's milk improves sugar absorption in diarrhoeic calves. The animals were rehydrated with an orally administered solution containing electrolytes and glucose. Thereafter the calves received one test meal of whole fresh cow's milk whose lactose had been hydrolysed by added lactase and one test meal of unprocessed cow's milk at an interval of 24 h in a cross-over design trial. In comparison with unprocessed milk, the intake of milk containing hydrolysed lactose resulted in a slight decrease of mean breath hydrogen concentration (P = 0.18), but also a slight decrease of mean blood galactose concentration (P = 0.14). There was no treatment effect on mean plasma glucose concentration. Peak plasma glucose and blood galactose concentration tended to be delayed after the intake of lactose-hydrolysed milk, which implies that gastric emptying was probably delayed. The results show that feeding milk which contains hydrolysed lactose does not significantly improve lactose utilization in calves that are suffering from benign infectious diarrhoea.
Gutzwiller
A
A
Swiss Federal Research Station for Animal Production, Posieux, Switzerland. Andreas.Gutzwiller@rap.admin.ch
D000818:Animals; D019540:Area Under Curve; D001786:Blood Glucose / Q000032:analysis; D002417:Cattle; D002418:Cattle Diseases / Q000628:therapy*; D003967:Diarrhea / Q000628:therapy / Q000662:veterinary*; D005260:Female; D005690:Galactose / Q000097:blood / Q000502:physiology*; D005947:Glucose / Q000502:physiology*; D006859:Hydrogen / Q000032:analysis; D043322:Lactase; D008297:Male; D008892:Milk / Q000201:enzymology; D015532:Rehydration Solutions / Q000008:administration & dosage; D001616:beta-Galactosidase / Q000008:administration & dosage*
D001786:Blood Glucose; D015532:Rehydration Solutions; D006859:Hydrogen; D043322:Lactase; D001616:beta-Galactosidase; D005947:Glucose; D005690:Galactose