Biological effects and mechanism of action of farnesyl transferase inhibitors.
Ashar
H R
HR
Department of Tumor Biology and Chemistry, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, USA.
Armstrong
L
L
James
L J
LJ
Carr
D M
DM
Gray
K
K
Taveras
A
A
Doll
R J
RJ
Bishop
W R
WR
Kirschmeier
P T
PT
D019883:Alkyl and Aryl Transferases / Q000037:antagonists & inhibitors*; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002453:Cell Cycle / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D016159:Tumor Suppressor Protein p53 / Q000502:physiology
D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D016159:Tumor Suppressor Protein p53; D019883:Alkyl and Aryl Transferases; C064911:p21(ras) farnesyl-protein transferase