Optically active N-acetyldopamine dimer of the crude drug "Zentai," the cast-off shell of the Cicada, Cryptotympana sp.
Two optically active N-acetyldopamine dimers together with four phenolic monomers were isolated from the crude drug "Zentai," a cast-off shell of the cicada of Cryptotympana sp. (Cicadidae). The former two were 2-(3',4'-dihydroxyphenyl)-1,4-benzodioxane derivatives carrying substituents at the 3 and 6 (or 7) positions, which are known to be components of sclerotized insect cuticles. Their structures including absolute configurations were determined on the basis of NMR and circular dichroism (CD) spectroscopic data.
Noda
N
N
Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Osaka, Japan. noda@pharm.setsunan.ac.jp
Kubota
S
S
Miyata
Y
Y
Miyahara
K
K
D000818:Animals; D004298:Dopamine / Q000031:analogs & derivatives* / Q000737:chemistry; D006430:Hemiptera / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008516:Medicine, Chinese Traditional; D008745:Methylation; D008968:Molecular Conformation; D010636:Phenols
D010636:Phenols; C006374:N-acetyldopamine; D004298:Dopamine