title: [Studies on organofluorine compounds: an overview of our 30 years].
abstract: This review article covers our research activities over 30 years in organofluorine chemistry. The followings are briefly summarized researches in this memorandum: (1) Trifluoromethylation of organic halides with trifluoromethyl copper complex and its application to trifluoromethylated nucleosides, (2) a systematic study on reactivity of aromatic trifluoromethyl compounds, (3) valence bond isomers of aromatic compounds stabilized by the trifluoromethyl groups, and (4) synthesis of fluorinated bioactive compounds which involve vitamin D3, arachidonic acid and its metabolites, and retinal.
authors.affiliation: Tokyo University of Pharmacy & Life Science, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: T
authors.initials: T
authors.lastname: Taguchi
mesh_terms: D002625:Chemistry, Organic / Q000266:history*; D002762:Cholecalciferol; D005459:Fluorides / Q000737:chemistry / Q000266:history; D049673:History, 20th Century; D006801:Humans; D007975:Leukotriene B4; D012172:Retinaldehyde
chemical_list: D002762:Cholecalciferol; D007975:Leukotriene B4; D005459:Fluorides; D012172:Retinaldehyde