title: An IBM PC-based system for experimental haemodynamic studies.
abstract: An IBM PC-based real-time data acquisition, monitoring and analysis system for experimental haemodynamic studies was developed. Comprehensive haemodynamic signals, such as aortic and left ventricular pressures, aortic and coronary blood flows, two segmental lengths, two segmental thicknesses, electrocardiogram and airway pressure, were acquired and monitored to assess cardiac function. The system performs computer-aided analysis and derivations on a number of haemodynamic parameters and cardiac function indices. The system has been tested and validated extensively over a number of series of experimental haemodynamic studies to investigate the effects of anaesthetic agents, cardiovascular drugs, and changes in loading on normal and critically ischaemic myocardium of anaesthetised laboratory subjects. Without this specialised and automated system, the analysis of the data acquired from the haemodynamic studies would be too time-consuming and could not be fully performed.
authors.affiliation: Nuffield Department of Anaesthetics, Radcliffe Infirmary, Woodstock Road, OX2 6HE, Oxford, UK. lawd.wong@nda.ox.ac.uk
authors.forename: L S
authors.initials: LS
authors.lastname: Wong
authors.forename: S C
authors.initials: SC
authors.lastname: Marsch
authors.forename: S
authors.initials: S
authors.lastname: Dalmas
authors.forename: P
authors.initials: P
authors.lastname: Foëx
mesh_terms: D001794:Blood Pressure / Q000502:physiology; D003971:Diastole / Q000502:physiology; D004562:Electrocardiography / Q000295:instrumentation; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D017202:Myocardial Ischemia / Q000150:complications; D015428:Myocardial Reperfusion Injury / Q000175:diagnosis* / Q000209:etiology; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D012986:Software Validation; D013318:Stroke Volume; D016277:Ventricular Function, Left / Q000502:physiology