Structural biology with carbon nanotube AFM probes.
Carbon nanotubes represent ideal probes for high-resolution structural and chemical imaging of biomolecules with atomic force microscopy. Recent advances in fabrication of carbon nanotube probes with sub-nanometer radii promise to yield unique insights into the structure, dynamics and function of biological macromolecules and complexes.
Woolley
A T
AT
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA.
Cheung
C L
CL
Hafner
J H
JH
Lieber
C M
CM
D000818:Animals; D002244:Carbon / Q000737:chemistry*; D006801:Humans; D018625:Microscopy, Atomic Force / Q000295:instrumentation / Q000379:methods*; D008854:Microscopy, Electron; D008954:Models, Biological; D008958:Models, Molecular; D015336:Molecular Probe Techniques; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry / Q000648:ultrastructure*; D013329:Structure-Activity Relationship
D011506:Proteins; D002244:Carbon