title: Fine needle aspiration cytology of undifferentiated embryonal sarcoma of the liver: a case report.
abstract: The cytological features of a rare case of undifferentiated (embryonal) sarcoma of the liver are presented. The cytology smears showed singly dispersed polygonal and spindle cells as well as loose clusters of cells held together in myxoid material. Neoplastic cells were generally large with round, oval or lobulated nuclei. The cytoplasm was variable in amount with ill-defined borders. Occasional multinucleated cells were also present. Hyaline globules were present on sections of the cell block. Immunohistochemical studies performed showed positivity for vimentin, cytokeratin and alpha-1-antitrypsin (AAT) in the tumour cells.
authors.affiliation: Department of Pathology, Universiti Kebangsaan Malaysia.
authors.forename: N A
authors.initials: NA
authors.lastname: Sharifah
authors.forename: W M
authors.initials: WM
authors.lastname: Muhaizan
authors.forename: J
authors.initials: J
authors.lastname: Rahman
authors.forename: A
authors.initials: A
authors.lastname: Zulfikar
authors.forename: Z
authors.initials: Z
authors.lastname: Zahari
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001707:Biopsy, Needle; D002648:Child; D003520:Cyclophosphamide / Q000008:administration & dosage; D003609:Dactinomycin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006498:Hepatectomy; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008113:Liver Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D009373:Neoplasms, Germ Cell and Embryonal / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome; D014746:Vimentin / Q000032:analysis; D014750:Vincristine / Q000008:administration & dosage; D000515:alpha 1-Antitrypsin / Q000032:analysis
chemical_list: D014746:Vimentin; D000515:alpha 1-Antitrypsin; D003609:Dactinomycin; D014750:Vincristine; D007633:Keratins; D004317:Doxorubicin; D003520:Cyclophosphamide