Synthesis of melithasterol A, a 5alpha,6alpha-epoxy-7alpha-hydroxy Delta(8)-steroid.
A short, first synthesis of melithasterol A (3) utilizing microwave irradiation-induced isomerization of 5alpha,8alpha-epidioxy steroid (1) as the key step has been achieved in 80% yield.
Ramesh
P
P
Natural Products Laboratory, Organic Division-I, Indian Institute of Chemical Technology, Hyderabad, 500 007, India.
Reddy
V L
VL
Reddy
N S
NS
Venkateswarlu
Y
Y
D013261:Sterols / Q000138:chemical synthesis*
D013261:Sterols; C416567:melithasterol A