Function of tetraspan proteins in the myelin sheath.
During the past few years, significant advances have been made in elucidating the mechanisms by which point mutations and altered gene dosages in tetraspan genes cause neurological disease. In addition, several new myelin tetraspans have been identified that are involved in adhesion, molecular trafficking, growth regulation, and migration of oligodendrocytes and Schwann cells.
Bronstein
J M
JM
UCLA School of Medicine, Department of Neurology, Reed Neurological Research Center, 710 Westwood Plaza, Los Angeles, CA 90095, USA. jbronste@ucla.edu
D000818:Animals; D006801:Humans; D009186:Myelin Sheath / Q000378:metabolism / Q000502:physiology*; D009419:Nerve Tissue Proteins / Q000378:metabolism / Q000502:physiology*; D011510:Proteolipids / Q000737:chemistry / Q000378:metabolism
D009419:Nerve Tissue Proteins; D011510:Proteolipids