[Macrodiolides--chemical properties and activity in a biological model].
Diolides, often classified into a group of macrolides, represent a heterogenous group of microbial metabolites whose common feature is the presence of a cyclic diester moiety in their structure. These compounds have cytotoxic, antiviral, anthelmintic or immunosuppressive activities and they were effective agents against some autoimmune diseases. Diolides, contrary to macrolides, showed a substantially lower antibacterial activity. The current data on the chemical properties and biological activity of diolides are presented in this paper.
Proksa
B
B
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D018942:Macrolides; D015394:Molecular Structure
D000900:Anti-Bacterial Agents; D018942:Macrolides