title: Disappearance of intramolecular stacking due to one-atom movement or increment of a 'propylene linker' in pyrazolo[3,4-d]pyrimidine-based flexible models.
abstract: In the crystal structures of 4,6-dimethylthio-1-[3-(4, 6-dimethylthio-2H-pyrazolo[3, 4-d]pyrimidin-2-yl)propyl]-1H-pyrazolo[3,4-d]pyrimidine, C(17)H(20)N(8)S(4), and 1-[4-(4-methoxy-6-methylthio-1H-pyrazolo[3, 4-d]pyrimidin-1-yl)butyl]-5-methyl-6-methylthio-4, 5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-4-one, C(18)H(22)N(8)O(2)S(2), only intermolecular stacking due to aromatic pi-pi interactions between pyrazolo[3,4-d]pyrimidinerings is present.
authors.affiliation: Membrane Biology Division, Central Drug Research Institute, Lucknow 226 001, India. root@cscdri.ren.nic.in.
authors.forename: P R
authors.initials: PR
authors.lastname: Maulik
authors.forename: K
authors.initials: K
authors.lastname: Avasthi
authors.forename: S
authors.initials: S
authors.lastname: Sarkhel
authors.forename: T
authors.initials: T
authors.lastname: Chandra
authors.forename: D S
authors.initials: DS
authors.lastname: Rawat
authors.forename: B
authors.initials: B
authors.lastname: Logsdon
authors.forename: R A
authors.initials: RA
authors.lastname: Jacobson