title: Clear cell adenocarcinoma of the cervix associated with a rare genitourinary malformation.
abstract: BACKGROUND
  Cervical adenocarcinoma and genitourinary malformations are relatively common disorders, yet their coexistence is rare.
  
  
  METHODS
  A 49-year-old woman developed clear cell adenocarcinoma in the atretic hemicervix of a communicating uterus type 7 and had ipsilateral renal agenesis. Compared with the unaffected right hemicervix, only the tumor-involved glands of the atretic left hemicervix contained ciliated tuboendometrial cells. Four and a half years after radical hysterectomy and pelvic radiation, she showed no evidence of recurrence.
  
  
  CONCLUSIONS
  In contrast to current opinion, communicating uteri type 7 are associated with ipsilateral renal agenesis. Our histologic findings support the hypothesis that tuboendometrial cells are the cells of origin for cervical clear-cell adenocarcinoma.
authors.affiliation: Department of Obstetrics and Gynecology, University of Bern, Bern, Switzerland. stefan.spoerri@insel.ch
authors.forename: S
authors.initials: S
authors.lastname: Spörri
authors.forename: H J
authors.initials: HJ
authors.lastname: Altermatt
authors.forename: E
authors.initials: E
authors.lastname: Dreher
authors.forename: W
authors.initials: W
authors.lastname: Hänggi
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000150:complications* / Q000473:pathology; D002584:Cervix Uteri / Q000002:abnormalities; D005260:Female; D006801:Humans; D007668:Kidney / Q000002:abnormalities; D008875:Middle Aged; D014564:Urogenital Abnormalities / Q000150:complications*; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000473:pathology; D014621:Vagina / Q000002:abnormalities