Complete cDNA sequence and amino acid analysis of a bovine ribonuclease K6 gene.
The complete cDNA sequence of a ribonuclease k6 gene of Bos Taurus has been determined. It codes for a protein with 154 amino acids and contains the invariant cysteine, histidine and lysine residues as well as the characteristic motifs specific to ribonuclease active sites. The deduced protein sequence is 27 residues longer than other known ribonucleases k6 and shows amino acids exchanges which could reflect a strain specificity or polymorphism within the bovine genome. Based on sequence similarity we have termed the identified gene bovine ribonuclease k6 b (brk6b).
Pietrowski
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Lehrstuhl fur Tierzucht und Algemeine Landwirtschaftslethe, Universität München, Germany. Detlef.Pietrowski@gen.vet-med.uni-muenchen.de
Förster
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D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002417:Cattle / Q000235:genetics*; D018076:DNA, Complementary; D004722:Endoribonucleases / Q000737:chemistry* / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D011323:Primates; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D014714:Vertebrates
D018076:DNA, Complementary; D004722:Endoribonucleases; C101685:ribonuclease k6