Successful outcome of Scedosporium apiospermum disseminated infection treated with voriconazole in a patient receiving corticosteroid therapy.
A disseminated Scedosporium apiospermum infection was diagnosed in a woman with severe asthma and treated with corticosteroids. This fungi is resistant to fluconazole and amphotericin B. The infection was refractory to itraconazole, but responded successfully to voriconazole. A review of the literature is provided.
Muñoz
P
P
Department of Clinical Microbiology-Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain. pmunoz@micro.hggm.es
Marín
M
M
Tornero
P
P
Martín Rabadán
P
P
Rodríguez-Creixéms
M
M
Bouza
E
E
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use*; D001249:Asthma / Q000150:complications / Q000188:drug therapy; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D006801:Humans; D008172:Lung Diseases, Fungal / Q000188:drug therapy / Q000382:microbiology; D008271:Mycetoma / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D011743:Pyrimidines / Q000627:therapeutic use*; D021681:Scedosporium / Q000187:drug effects / Q000302:isolation & purification*; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use*; D065819:Voriconazole
D000305:Adrenal Cortex Hormones; D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole