The effect of two hydrophilic monomers on the water uptake of a heterocyclic methacrylate system.
The room temperature polymerising system poly(ethyl methacrylate) (PEM)/tetrahydrofurfuryl methcrylate (THFM) has been modified by replacing some of the THFM by hydroxyethyl methacrylate (HEMA) and hydroxypropyl methacrylate (HPM), respectively. In both cases, the equilibrium uptake of the parent system is reduced substantially, in spite of the hydrophilic nature of these monomers. The effect is less with HPM. Corresponding to these decreases in uptake are substantial increases in the diffusion coefficients. This points to changes from a cluster-dominated process, to a more continuum-based process in the dual monomer systems. Addition of chicken serum albumin to these systems increases water uptake. At higher levels of HEMA addition, there is a substantial increase in polymerisation exotherm.
Patel
M P
MP
Department of Biomaterials in Relation to Dentistry, IRC in Biomedical Materials, St Bartholomew's and the Royal London School of Medicine and Dentistry, Queen Mary and Westfield, UK.
Johnstone
M B
MB
Hughes
F J
FJ
Braden
M
M
D000042:Absorption; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D002645:Chickens; D004058:Diffusion; D007700:Kinetics; D008689:Methacrylates / Q000737:chemistry*; D008768:Methylmethacrylates / Q000737:chemistry*; D012709:Serum Albumin / Q000737:chemistry; D013816:Thermodynamics; D014867:Water
D001672:Biocompatible Materials; D008689:Methacrylates; D008768:Methylmethacrylates; D012709:Serum Albumin; D014867:Water; C092890:tetrahydrofurfuryl methacrylate; C005044:hydroxyethyl methacrylate; C009931:poly(ethylmethacrylate)