title: Fornix-based trabeculectomy with Wise's suture technique in Chinese patients.
abstract: OBJECTIVE
  To assess the safety and efficacy of fornix-based trabeculectomy with Wise's suture technique in Chinese subjects.
  
  
  METHODS
  A retrospective noncomparative case series.
  
  
  METHODS
  Forty-eight eyes of 44 Chinese subjects that underwent fornix-based trabeculectomy combined with intraoperative 0.4 mg/ml mitomycin-C for 3 to 5 minutes were studied.
  
  
  METHODS
  Conjunctival wound closure of all eyes was with the Wise's technique using 9-0 nylon suture to prevent leakage at the corneolimbal interface.
  
  
  METHODS
  The success rate, with or without antiglaucoma medication, the complication rate, and the longevity of the drainage blebs were analyzed.
  
  
  RESULTS
  At a mean follow-up period of 21.8 +/- 4.5 months, 75% (36 eyes) had postoperative intraocular pressure of 21 mmHg or less. Of these, 23 eyes (47.9%) required no antiglaucoma medication, 7 eyes (14.6%) required one medication, 3 eyes (6.3%) required two medications, and 3 eyes (6.3%) required three medications. Ten eyes (21%) had early wound leak. Two eyes (4.2%) required surgical repair. Two eyes (4%) had hypotonous maculopathy. No other major complications were encountered.
  
  
  CONCLUSIONS
  Fornix-based trabeculectomy with adjunctive mitomycin-C using Wise's suture technique appears to be both safe and effective in Chinese subjects.
authors.affiliation: Hospital Authority Ophthalmic Services, Hong Kong Eye Hospital, Kowloon, Hong Kong.
authors.forename: P W
authors.initials: PW
authors.lastname: Ng
authors.forename: B Y
authors.initials: BY
authors.lastname: Yeung
authors.forename: D W
authors.initials: DW
authors.lastname: Yick
authors.forename: C B
authors.initials: CB
authors.lastname: Yu
authors.forename: D S
authors.initials: DS
authors.lastname: Lam
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D044466:Asian People; D017024:Chemotherapy, Adjuvant; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000188:drug therapy / Q000208:ethnology / Q000601:surgery*; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000627:therapeutic use; D011183:Postoperative Complications; D012189:Retrospective Studies; D012449:Safety; D013536:Suture Techniques; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D016685:Mitomycin