title: Factors associated with osteoarthritis of the hip and knee in Hong Kong Chinese: obesity, joint injury, and occupational activities.
abstract: In 1998, a case-control study was conducted in Hong Kong on hospital patients with osteoarthritis of the hip (n = 138) and osteoarthritis of the knee (n = 658). Age- and sex-matched controls were recruited consecutively from general practice clinics in the same region. The following three risk factors were found to be associated with osteoarthritis of both the hip and the knee: first, a history of joint injury: for osteoarthritis of the hip, the odds ratio = 25.1 (95% confidence interval (CI): 3.5, 181) in men and 43.3 (95% CI: 11.7, 161) in women; for osteoarthritis of the knee, the odds ratio = 12.1 (95% CI: 3.4, 42.5) in men and 7.6 (95% CI: 3.8, 15.2) in women; second, climbing stairs frequently: for osteoarthritis of the hip, the odds ratio = 12.5 (95% CI: 1.5, 104.3) in men and 2.3 (95% CI: 0.6, 8.1) in women; for osteoarthritis of the knee, the odds ratio = 2.5 (95% CI: 1.0, 6.4) in men and 5.1 (95% CI: 2.5, 10.2) in women; third, lifting heavy weight frequently: for osteoarthritis of the hip, the odds ratio = 3.1 (95% CI: 0.7, 14.3) in men and 2.4 (95% CI: 1.1, 5.3) in women; for osteoarthritis of the knee, the odds ratio = 5.4 (95% CI: 2.4, 12.4) in men and 2.0 (95% CI: 1.2, 3.1) in women. In addition, subjects whose height and weight were in the highest quartile were at increased risk of osteoarthritis of the hip and knee, respectively (p < 0.05).
authors.affiliation: Department of Community and Family Medicine, The Chinese University of Hong Kong. edithlau@cuhk.edu.hk
authors.forename: E C
authors.initials: EC
authors.lastname: Lau
authors.forename: C
authors.initials: C
authors.lastname: Cooper
authors.forename: D
authors.initials: D
authors.lastname: Lam
authors.forename: V N
authors.initials: VN
authors.lastname: Chan
authors.forename: K K
authors.initials: KK
authors.lastname: Tsang
authors.forename: A
authors.initials: A
authors.lastname: Sham
mesh_terms: D000328:Adult; D001827:Body Height; D001835:Body Weight; D016022:Case-Control Studies; D005260:Female; D025981:Hip Injuries; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D007718:Knee Injuries / Q000150:complications; D017770:Lifting / Q000009:adverse effects; D016015:Logistic Models; D008297:Male; D009784:Occupational Diseases / Q000453:epidemiology* / Q000209:etiology; D015207:Osteoarthritis, Hip / Q000453:epidemiology* / Q000209:etiology; D020370:Osteoarthritis, Knee / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors; D017678:Sex Distribution; D012907:Smoking / Q000009:adverse effects; D013177:Sports