title: Extending the excitation sculpting concept for selective excitation.
abstract: Nowadays, excitation sculpting is probably the most efficient way to achieve selectivity in an NMR experiment, since it associates very clean frequency selection with "user-friendliness." In the present report, it is shown that the excitation sculpting concept, originally based on a double pulse field gradient echo acting on a selected transverse magnetization, can be extended through new experiments designed to act on longitudinal magnetization. This leads to outstanding performances, especially when the transverse relaxation rate is a limiting factor as, for example, in the case of biological macromolecules. Several new sequences are proposed, aiming at the selection of magnetization aligned either/both on a transverse axis or/and on the z-axis. Their potentialities are illustrated in light of different applications including multiplet-selective excitation, band-selective excitation, and water suppression.
authors.affiliation: Centre de Biochimie Structurale, CNRS-UMR 9955, INSERM-U414, Faculté de Pharmacie, Université de Montpellier I, 15 Avenue Charles Flahault, 34060 Montpellier Cedex 1, France. roume@cbs.univ-montp1.fr
authors.forename: C
authors.initials: C
authors.lastname: Roumestand
authors.forename: D
authors.initials: D
authors.lastname: Canet
mesh_terms: D000818:Animals; D004179:Cobra Cardiotoxin Proteins / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D010455:Peptides / Q000737:chemistry; D012503:Saponins / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D004179:Cobra Cardiotoxin Proteins; D010455:Peptides; D012503:Saponins; D014867:Water