A seroprevalence study of viral hepatitis E infection in human immunodeficiency virus type 1 infected subjects in Malaysia.
Hepatitis E virus (HEV) is a RNA virus transmitted enterically. A study of anti-HEV antibodies in 145 human immunodeficiency virus type 1 (HIV-1) infected subjects found that 14.4% of them were reactive to anti-HEV antibodies. Anti-HEV IgG and anti-HEV IgM was detected in 10.3% and 4.1% of the subjects respectively. Prevalence of anti-HEV (either IgG or IgM) was similar across all adult ages (p = 0.154), between the three ethnic groups (p = 0.378), and across risk groups (p = 0.120). The results showed that HEV infection in subjects recruited in this study was most likely transmitted via faecal-route.
Ng
K P
KP
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
He
J
J
Saw
T L
TL
Lyles
C M
CM
D000328:Adult; D002648:Child; D002675:Child, Preschool; D015658:HIV Infections / Q000276:immunology* / Q000821:virology*; D015497:HIV-1; D016751:Hepatitis E / Q000276:immunology*; D006801:Humans; D007223:Infant; D008296:Malaysia; D016036:Seroepidemiologic Studies