Muscular dystrophy: the worm turns to genetic disease.
A new animal model for studying muscular dystrophy, a mutant form of the nematode Caenorhabditis elegans, brings the power of worm genetics to bear on the search for a cure for this disease; work on this worm has already led to the identification of a novel component that can suppress the mutant phenotype.
Chamberlain
J S
JS
Department of Human Genetics, Center for Gene Therapy, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA. chamberl@unimich.edu
Benian
G M
GM
D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics*; D004195:Disease Models, Animal; D016189:Dystrophin / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D008954:Models, Biological; D018482:Muscle, Skeletal / Q000502:physiology; D020388:Muscular Dystrophy, Duchenne / Q000235:genetics* / Q000503:physiopathology; D009154:Mutation
D016189:Dystrophin