title: CPH 82 (Reumacon) in refractory inflammatory arthritis.
abstract: In this retrospective analysis of the DMARD CPH 82 in 44 Icelandic patients with severe refractory arthritis, clinical tolerance was good and serious side effects absent, although the majority were using the drug in combination with other DMARDS. Side effects leading to discontinuation were seen in 16% and the three year drug-survival was 51%.
authors.affiliation: Landspitalinn University Hospital, Reykjavik, Iceland.
authors.forename: E S
authors.initials: ES
authors.lastname: Gudmundsdóttir
authors.forename: H
authors.initials: H
authors.lastname: Jónsson
mesh_terms: D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use*; D018501:Antirheumatic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D006027:Glycosides / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D017705:Lignans / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors; D017211:Treatment Failure; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D018501:Antirheumatic Agents; C059428:CPH 82; D006027:Glycosides; D017705:Lignans