title: Melkersson-Rosenthal syndrome in childhood: a challenge in differential diagnosis and treatment.
abstract: Facial palsy and orofacial swelling in childhood represent a challenge in differential diagnosis for paediatricians and dermatologists. One possible entity, Melkersson-Rosenthal syndrome (MRS), is a rarity in childhood. We describe a 9-year-old girl with the diagnosis of MRS who had episodic swelling of the upper lip and complete peripheral facial palsy, associated with herpes and recurrent bacterial infections. Therapeutic options for MRS in childhood are limited. Our patient benefited from a 2-month course of prednisolone 1 mg kg(-1) daily. We review previously published cases of MRS in childhood, and discuss the differential diagnosis of orofacial swelling and facial palsy as well as treatment options in children.
authors.affiliation: Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, H. Fabecstr. 60-62, 14195 Berlin, Germany.
authors.forename: P E
authors.initials: PE
authors.lastname: Ziem
authors.forename: C
authors.initials: C
authors.lastname: Pfrommer
authors.forename: S
authors.initials: S
authors.lastname: Goerdt
authors.forename: C E
authors.initials: CE
authors.lastname: Orfanos
authors.forename: U
authors.initials: U
authors.lastname: Blume-Peytavi
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008556:Melkersson-Rosenthal Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone