title: Psychological well-being in patients with primary Sjögren's syndrome.
abstract: OBJECTIVE
  To evaluate quality of life and psychological symptoms in patients with primary Sjögren's syndrome and to compare this with patients with rheumatoid arthritis.
  
  
  METHODS
  A standardised questionnaire, the Psychological General Well-Being Index (PGWB), was used to examine the quality of life and psychological symptoms in patients with primary Sjögren's syndrome (pSS; n = 34). Patients with rheumatoid arthritis (RA; n = 32) were used as patient controls.
  
  
  RESULTS
  The total mean score +/- SD for PGWB was 84.9 +/- 16.2 in pSS patients and significantly lower (p = 0.001) than in RA patients (97.7 +/- 17.5). Patients with pSS had an increased propensity for depressed mood (p = 0.0009), and suffered from reduced well-being (p = 0.002) and impaired vitality (p = 0.003).
  
  
  CONCLUSIONS
  The results suggest that patients with pSS have a reduced quality of life, a higher degree of distress and a lower sense of well-being than patients with RA.
authors.affiliation: Department of Medical Sciences-Rheumatology, University Hospital Uppsala, Sweden. sigridur.valtysdottir@medicin.uu.se
authors.forename: S T
authors.initials: ST
authors.lastname: Valtýsdóttir
authors.forename: B
authors.initials: B
authors.lastname: Gudbjörnsson
authors.forename: R
authors.initials: R
authors.lastname: Hällgren
authors.forename: J
authors.initials: J
authors.lastname: Hetta
mesh_terms: D000328:Adult; D000368:Aged; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy / Q000523:psychology; D003863:Depression / Q000209:etiology; D005260:Female; D006801:Humans; D008603:Mental Health; D008875:Middle Aged; D011788:Quality of Life; D012859:Sjogren's Syndrome / Q000523:psychology*
chemical_list: D018501:Antirheumatic Agents