title: [Effect of immunization to cholecystokinin fragment (30-33) on the behavior of albino rats].
abstract: Active immunisation of albino rats by the BSA-conjugated CCK-4 induced formation of antibodies to the CCK-4 and some long-term changes of the rat behaviour. These changes were contrary to anxiogenic effect of the CCK-4 and demonstrated an anxiolytic effect of the immunisation. The data obtained suggest a possibility of an immunocorrection of pathological anxiety and fear by an inverse immunoregulation.
authors.affiliation: Moscow State University, Vorobyevy Gory.
authors.forename: R A
authors.initials: RA
authors.lastname: Danilova
authors.forename: O I
authors.initials: OI
authors.lastname: Rud'ko
authors.forename: T M
authors.initials: TM
authors.lastname: Korotkova
authors.forename: M F
authors.initials: MF
authors.lastname: Obukhova
authors.forename: I P
authors.initials: IP
authors.lastname: Ashmarin
mesh_terms: D000428:Alcohol Drinking; D000818:Animals; D000906:Antibodies / Q000097:blood / Q000737:chemistry / Q000494:pharmacology*; D001362:Avoidance Learning / Q000187:drug effects; D001522:Behavior, Animal / Q000187:drug effects*; D004797:Enzyme-Linked Immunosorbent Assay; D005106:Exploratory Behavior / Q000187:drug effects; D018782:Maze Learning / Q000187:drug effects; D009043:Motor Activity / Q000187:drug effects; D017288:Pain Threshold; D051381:Rats; D017208:Rats, Wistar; D012709:Serum Albumin / Q000737:chemistry; D013758:Tetragastrin / Q000276:immunology* / Q000494:pharmacology; D014611:Vaccination
chemical_list: D000906:Antibodies; D012709:Serum Albumin; D013758:Tetragastrin