Therapeutic potential of plant sterols and stanols.
Products enriched with plant sterol and stanol esters selectively lower LDL cholesterol. Consumption appears to be safe, and these functional foods thus have great potential for cardiovascular risk management. Although values remain within the normal range, one possible concern is that they lower lipid-standardized concentrations of the plasma carotenoids. Whether this affects health in the longer-term or in selected patient groups is not known. Therefore, especially in view of the increasing number of functional foods that will be on the market in the very near future, there is a clear need to establish an effective post-marketing safety net.
Plat
J
J
Department of Human Biology, Maastricht University, Maastricht, the Netherlands.
Kerckhoffs
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DA
Mensink
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RP
D000975:Antioxidants / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000517:prevention & control; D002338:Carotenoids / Q000097:blood; D008078:Cholesterol, LDL / Q000737:chemistry / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005527:Food, Fortified; D006801:Humans; D010840:Phytosterols / Q000627:therapeutic use*; D012307:Risk Factors; D012855:Sitosterols / Q000627:therapeutic use*; D014815:Vitamins / Q000097:blood
D000975:Antioxidants; D008078:Cholesterol, LDL; D010840:Phytosterols; D012855:Sitosterols; D014815:Vitamins; C407042:plant stanol ester; D002338:Carotenoids