title: Severe acute lung injury caused by Mycoplasma pneumoniae: potential role for steroid pulses in treatment.
abstract: Published evidence of pathogenetic mechanisms of acute respiratory distress syndrome (ARDS) in mycoplasmal lung infections suggests that the pulmonary injury is related to a cell-mediated immune response. Therefore, steroids may play a role in the treatment of severe cases. We describe a patient who had Mycoplasma pneumoniae pneumonia that progressed to severe ARDS requiring mechanical ventilation and who had improvement with prednisolone pulses.
authors.affiliation: Internal Medicine Department, Sanatorio de la Trinidad, Capital Federal, Argentina. mradisic@intramed.net.ar
authors.forename: M
authors.initials: M
authors.lastname: Radisic
authors.forename: A
authors.initials: A
authors.lastname: Torn
authors.forename: P
authors.initials: P
authors.lastname: Gutierrez
authors.forename: H A
authors.initials: HA
authors.lastname: Defranchi
authors.forename: P
authors.initials: P
authors.lastname: Pardo
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009177:Mycoplasma pneumoniae / Q000472:pathogenicity*; D011019:Pneumonia, Mycoplasma / Q000150:complications* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use*; D012128:Respiratory Distress Syndrome / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone