[The effects of the combined use of mineral water with ascorbic acid and rutin experimentally and clinically].
Effects of a single and course intake of glucose, ascorbic acid and rutin in combination with mineral water Essentuki N17 on blood levels of glucose, hydrocortisone, ACTH, insulin were studied in 336 Wistar male rats. 80 patients with diabetes mellitus type I and II received a course of ascorutin and mineral water. Mineral water proved able to reduce a hyperglycemic effect of vitamins. A course of mineral water and ascorutin promotes improvement of carbohydrate, lipid metabolism, elevates plasma content of ascorbic acid, diminishes the need in sugar-reducing drugs.
Polushina
N D
ND
Kartazaeva
V A
VA
Botvineva
L A
LA
Kozhevnikov
S A
SA
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology / Q000627:therapeutic use*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005947:Glucose / Q000008:administration & dosage; D006728:Hormones / Q000097:blood; D006801:Humans; D008297:Male; D008900:Mineral Waters / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D012431:Rutin / Q000494:pharmacology / Q000627:therapeutic use*; D013997:Time Factors
D006728:Hormones; D008900:Mineral Waters; D012431:Rutin; D005947:Glucose; D001205:Ascorbic Acid