title: [The monitoring of the drug resistance of the causative agent of tuberculosis in Russia in 1979-1998].
abstract: The Russian 1979-1998 annual reports of the centralized microbiology laboratories of the tuberculosis controlling service were used to examine the pattern and trends of formation of drug-resistance in the tuberculosis pathogen. The data on over 1.2 million cases of drug resistance to 7 antituberculous drugs were pooled. The analysis indicated that drug resistance had increased in two steps in the past 2 decades. The maximum levels of the drug resistance of Mycobacterium tuberculosis to some drugs were limited (7.8 and 37.2%), which are not greater those as indicated by the international statistics.
authors.forename: I R
authors.initials: IR
authors.lastname: Dorozhkova
authors.forename: S A
authors.initials: SA
authors.lastname: Popov
authors.forename: I M
authors.initials: IM
authors.lastname: Medvedeva
mesh_terms: D000995:Antitubercular Agents / Q000037:antagonists & inhibitors*; D016903:Drug Monitoring / Q000706:statistics & numerical data / Q000639:trends; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D012426:Russia; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents