title: The use of rizatriptan in the treatment of acute, multiple migraine attacks.
abstract: Therapy for migraine can be classified as preventive or acute. Preventive therapy is intended to reduce the frequency of headache, whereas the goal of acute migraine therapy is to optimize the patient's ability to function by reversing, aborting, or reducing pain and migraine-associated symptoms. Rizatriptan is a new, selective 5-HT1B/1D receptor agonist that is effective for treatment of migraine. Clinical studies of this drug have demonstrated its efficacy, safety, and tolerability when used as therapy for acute attacks on multiple occasions.
authors.affiliation: Michigan Head Pain and Neurological Institute, Ann Arbor, MI 48104, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Saper
mesh_terms: D000208:Acute Disease; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy* / Q000503:physiopathology*; D012008:Recurrence; D017366:Serotonin Receptor Agonists / Q000627:therapeutic use*; D014230:Triazoles / Q000627:therapeutic use*; D014363:Tryptamines
chemical_list: D017366:Serotonin Receptor Agonists; D014230:Triazoles; D014363:Tryptamines; C093622:rizatriptan