title: Deviant neurophysiological asymmetry in children with language impairment.
abstract: Deviant anatomical asymmetry of perisylvian cortex is argued to be linked to specific language impairment (SLI). However, no studies have examined whether deviant functional asymmetry underlies the processing of spoken language. In the current study, brain-electrical activity was recorded from 31 scalp sites to the function word 'the' embedded in auditorally presented stories and nonsense contexts. The SLI children showed reversed asymmetry at electrode sites over temporal cortex compared to control children in processing this word in all contexts. They also appear to lack some contribution from a deep neural generator in processing 'the' in the story. This investigation is the first to demonstrate a direct link between deviant neurophysiological asymmetry and the processing of spoken language in children with SLI.
authors: Department of Otolaryngology, Albert Einstein College of Medicine, Bronx, NY, USA.
authors: V L
authors: VL
authors: Shafer
authors: R G
authors: RG
authors: Schwartz
authors: M L
authors: ML
authors: Morr
authors: K L
authors: KL
authors: Kessler
authors: D
authors: D
authors: Kurtzberg
mesh_terms: D001931:Brain Mapping; D002540:Cerebral Cortex / Q000503:physiopathology*; D002648:Child; D004569:Electroencephalography; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007806:Language Disorders / Q000503:physiopathology*; D008297:Male; D013067:Speech Perception / Q000502:physiology