Mass spectrometry of bis-quinolizidine alkaloids: 2- and 17-alkyl-substituted derivatives of sparteine and lupanine.
The mass spectral fragmentations of 2-methylsparteine (1), 2, 17-dimethylsparteine (2), 2-methyl-17-isopropylsparteine (3), 2-methyl-17-oxosparteine (4), 2-oxo-17-methylsparteine (17-methyllupanine) (5) and 2-oxo-17-isopropylsparteine (17-isopropyllupanine) (6) were investigated. Fragmentation pathways, whose identification was assisted by accurate mass measurements and a correlation between the abundances of the M(+.) and selected fragment ions of the investigated compounds, are discussed. The data obtained create the basis for distinguishing the structural isomers and metamers.
Wyrzykiewicz
E
E
Faculty of Chemistry, A. Mickiewicz University, Grunwaldzka 6, 60-780 Poznań, Poland.
Boczoń
W
W
Koziol
B
B
D000470:Alkaloids / Q000032:analysis / Q000737:chemistry* / Q000378:metabolism; D001952:Bridged-Ring Compounds / Q000032:analysis / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods*; D008968:Molecular Conformation; D015394:Molecular Structure; D011807:Quinolizines / Q000032:analysis / Q000737:chemistry* / Q000378:metabolism; D013034:Sparteine / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000378:metabolism; D013237:Stereoisomerism
D000470:Alkaloids; D001952:Bridged-Ring Compounds; D011807:Quinolizines; C008298:lupanine; D013034:Sparteine