title: Strongyloides stercoralis infection and chronological changes of other soil-transmitted helminthiases in an endemic area of southern Thailand.
abstract: A field survey was conducted in 4 primary schools in Nakhon Si Thammarat Province, southern Thailand. By Sasa modified Harada-Mori cultivation method, 1.8% of the schoolchildren were found to be infected with Strongyloides stercoralis, and 25.1% had hookworm infection. By Kato's thick smear method, the overall prevalence of soil-transmitted helminths was 46.8%, being Trichuris trichiura 28.5%, hookworm 18.0%, and Ascaris lumbricoides 5.7%. Fecal examination, performed by Kato's thick smear and culture method, indicated that the prevalence of hookworm infection was 26.9%. The prevalence in the present study was very much lower than many previous reports in the past decade. This may indicate the partial success of the parasite control project in Thailand by mass treatment, improving the sanitation and personal hygiene of the people in the endemic area. In light infection with Trichuris, albendazole administered at a dosage of 200 mg daily for 3 days showed a 48.7% cure rate. When mebendazole was given at 100 mg twice daily for 3 days, its effectiveness was 88.5%. A lower cure rate was obtained (70.0%) in moderate to heavy infection.
authors: Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
authors: M T
authors: MT
authors: Anantaphruti
authors: S
authors: S
authors: Nuamtanong
authors: C
authors: C
authors: Muennoo
authors: S
authors: S
authors: Sanguankiat
authors: S
authors: S
authors: Pubampen
mesh_terms: D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use; D001196:Ascariasis / Q000453:epidemiology; D002648:Child; D019353:Endemic Diseases; D005243:Feces / Q000469:parasitology; D006373:Helminthiasis / Q000453:epidemiology*; D006725:Hookworm Infections / Q000453:epidemiology; D006801:Humans; D008463:Mebendazole / Q000627:therapeutic use; D015995:Prevalence; D012987:Soil / Q000469:parasitology; D017171:Strongyloides stercoralis; D013322:Strongyloidiasis / Q000453:epidemiology*; D013785:Thailand / Q000453:epidemiology; D014257:Trichuriasis / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D000969:Antinematodal Agents; D012987:Soil; D008463:Mebendazole; D015766:Albendazole