[Intra-individual comparison of intraocular lenses of highly refractive silicone (Allergan SI40NB) and hydrophobic acrylate (Alcon Acrysof MA60BM). 1-year follow-up].
BACKGROUND
A prospective, randomized study was performed to evaluate intra-individually the biocompatibility of foldable, highly refractive silicone and hydrophobic acrylic intraocular lenses (IOL).


METHODS
We studied 35 patients who underwent phacoemulsification using a self-sealing tunnel incision. In a randomized fashion one eye received a 6-mm optic IOL made of high-refractive index silicone (Allergan SI40NB) and the other eye a hydrophobic acrylic 6-mm optic IOL (Alcon AcrySof MA60BM). All patients were examined 7 days, 1-3 and 6 months, and 1 year postoperatively.


RESULTS
The mean best-corrected visual acuity (BCVA) was 0.9 +/- 0.12 vs. 0.89 +/- 0.13 (SI40NB vs. MA60BM) after 1-3 months. One-year postoperatively BCVA was still 0.9 +/- 0.12 vs. 0.87 +/- 0.14. The flare values (photon counts/ms) increased slightly 7 days after surgery (14.2 +/- 8.68 vs. 15.49 +/- 7.2, n.s.). Three months after surgery these values were again in the normal range. The mean IOL decentration was 0.29 +/- 0.14 vs. 0.3 +/- 0.15 mm 1 year postoperatively. Scheimpflug slit photography showed 40% of MA60BM IOLs to have "glistenings." No significant difference regarding posterior capsular opacification was found.


CONCLUSIONS
One year after implantation of foldable, highly refractive silicone and hydrophobic acrylic IOLs using a self-sealing tunnel incision and phacoemulsification, no significant functional or morphological differences between the two IOL types were observed.
Allers
A
A
Johann Wolfgang Goethe-Universität, Zentrum für Augenheilkunde, Frankfurt am Main.
Baumeister
M
M
Steinkamp
G W
GW
Ohrloff
C
C
Kohnen
T
T
D000179:Acrylates; D000368:Aged; D000369:Aged, 80 and over; D001672:Biocompatible Materials; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007910:Lenses, Intraocular; D008297:Male; D011183:Postoperative Complications / Q000209:etiology; D011446:Prospective Studies; D012828:Silicones
D000179:Acrylates; D001672:Biocompatible Materials; D012828:Silicones