Macular ischaemia in Behçet's disease.
OBJECTIVE
To report macular ischaemia and visual loss in patients with panuveitis due to Behçet's disease.


METHODS
We describe macular ischaemia, a rare finding, in 3 eyes of 3 patients with panuveitis who were diagnosed and treated as having Behçet's disease. The patients underwent fundus fluorescein angiography (FFA) using a digital imaging system and were treated with topical and oral steroids and cyclosporine in 2 cases, and with added azathioprine in the third case.


RESULTS
The 3 eyes showed macular ischaemia associated with peripheral retinal vasculitis on FFA and control of inflammation was achieved in all cases. After an average of 2 years follow-up, visual acuity and macular ischaemia improved in 2 eyes, while no recovery was seen in the third.


CONCLUSIONS
The presence of macular ischaemia on FFA in Behçet's disease is a predictor of poor visual outcome. Macular ischaemia may show partial recovery with the treatment of the disease.
Yilmaz
G
G
Başkent University School of Medicine, Department of Ophthalmology, Ankara, Turkey. gurselyilmaz@hotmail.com
Akova
Y
Y
Aydin
P
P
D000328:Adult; D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis*; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D007511:Ischemia / Q000150:complications / Q000175:diagnosis*; D008266:Macula Lutea / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D015864:Panuveitis / Q000150:complications / Q000175:diagnosis