Examination of regulatory cross-talk between the decay accelerating factor-binding fimbrial/afimbrial adhesins and type I fimbriae.
The revised sequence of DaaA means that the protein is 98% identical to the afimbrial adhesin regulator AFAA-III. While PapB repressed FimB OFF to ON switching in strain AAEC370A, this was not the case for DaaA. PapB, but not DaaA, reduced the level of expression of type 1 fimbriae, in static LB media. Attention is now focused on the amino terminus of the PapB protein as the possible domain involved in cross talk with type 1 fimbriae.
Holden
N
N
Department of Veterinary Pathology, Royal (Dick) School of Veterinary Studies, University of Edinburgh.
Cotterill
C
C
Gally
D
D
D000595:Amino Acid Sequence; D001422:Bacterial Adhesion / Q000502:physiology*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D018958:CD55 Antigens / Q000502:physiology*; D003001:Cloning, Molecular; D004926:Escherichia coli / Q000235:genetics / Q000472:pathogenicity / Q000502:physiology*; D029968:Escherichia coli Proteins; D010861:Fimbriae, Bacterial / Q000235:genetics / Q000502:physiology*; D006801:Humans; D008565:Membrane Proteins; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D014157:Transcription Factors / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
D001426:Bacterial Proteins; D018958:CD55 Antigens; C080953:DaaA protein, E coli; D029968:Escherichia coli Proteins; D008565:Membrane Proteins; D014157:Transcription Factors; C116245:atpD protein, E coli