Pathogenesis of Proteus mirabilis urinary tract infection.
Proteus mirabilis is a causative agent of cystitis and pyelonephritis primarily in individuals with indwelling catheters or structural abnormalities of the urinary tract. The organism produces a variety of unique virulence factors that contribute to its pathogenicity and persistence in the human host.
Coker
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Department of Microbiology and Immunology, University of Maryland, 655 W. Baltimore St., Baltimore, Maryland 21201, USA.
Poore
C A
CA
Li
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X
Mobley
H L
HL
D000581:Amidohydrolases / Q000378:metabolism; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism; D007501:Iron / Q000378:metabolism; D008297:Male; D008666:Metalloendopeptidases / Q000502:physiology; D011512:Proteus Infections / Q000276:immunology / Q000378:metabolism / Q000382:microbiology*; D011513:Proteus mirabilis / Q000378:metabolism / Q000472:pathogenicity*; D011704:Pyelonephritis / Q000378:metabolism / Q000382:microbiology; D001743:Urinary Bladder / Q000382:microbiology; D014552:Urinary Tract Infections / Q000276:immunology / Q000378:metabolism / Q000382:microbiology*
D007070:Immunoglobulin A; D007501:Iron; D008666:Metalloendopeptidases; C095666:serralysin; D000581:Amidohydrolases