title: Is epidural analgesia associated with an improved outcome following open Nissen fundoplication?
abstract: Postoperative epidural analgesia is increasingly popular in paediatric practice, although evidence of its benefit is scarce. We performed a retrospective analysis of a series of 104 consecutive open Nissen fundoplications, to determine whether mode of analgesia, epidural (n=65) or opioid infusion (n=39), influenced certain outcome measures, including intensive care utilization, duration of hospital stay, morbidity and mortality. The two groups were similar in terms of demographic characteristics and associated pathologies. Overall, morbidity and mortality (2%) rates were low. Mean duration of hospital stay was significantly greater for the opioid group, compared to those receiving epidural analgesia (13 vs. 8 days, P < 0.05). The number of patients who remained in hospital for more than 7 days was also significantly greater in the opioid group. Accepting the limitations of a retrospective study, these data suggest that epidural analgesia might be associated with an improved outcome following Nissen fundoplication and this merits a prospective study.
authors: Department of Anaesthesia, Leeds Teaching Hospitals NHS Trust, The General Infirmary at Leeds, Leeds, UK.
authors: G A
authors: GA
authors: Wilson
authors: J L
authors: JL
authors: Brown
authors: D G
authors: DG
authors: Crabbe
authors: W
authors: W
authors: Hinton
authors: P J
authors: PJ
authors: McHugh
authors: M D
authors: MD
authors: Stringer
mesh_terms: D000293:Adolescent; D015360:Analgesia, Epidural; D000701:Analgesics, Opioid / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D005260:Female; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000601:surgery; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous; D007362:Intensive Care Units; D007902:Length of Stay; D008297:Male; D010149:Postoperative Pain / Q000628:therapy*; D011183:Postoperative Complications; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000701:Analgesics, Opioid