title: Improved synthesis of the iodine-free thyromimetic GC-1.
abstract: Synthesis of the TRbeta-selective thyromimetic GC-1 has been improved using methoxymethyl (MOM) and triisopropylsilyl (TiPS) substituents as phenolic protecting groups. The new synthetic route is adaptable to analogue design.
authors: Department of Pharmaceutical Chemistry, University of California, San Francisco 94143-0446, USA.
authors: G
authors: G
authors: Chiellini
authors: N H
authors: NH
authors: Nguyen
authors: H A
authors: HA
authors: Yoshihara
authors: T S
authors: TS
authors: Scanlan
mesh_terms: D007455:Iodine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D018716:Molecular Mimicry; D013963:Thyroid Hormones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D013963:Thyroid Hormones; D007455:Iodine