Identification of derivatives of bisphenol A diglycidyl ether and novolac glycidyl ether in can coatings by liquid chromatography/ion trap mass spectrometry.
A reversed-phase liquid chromatographic method combined with fluorescence and multiple mass spectrometric detection in series is presented for the separation and structure elucidation of bisphenol A diglycidyl ether (BADGE) and novolac glycidyl ether (NOGE) derivatives. Atmospheric pressure chemical ionization in the positive ion mode and collision induced fragmentation in the ion trap allowed identification of BADGE- and NOGE-related compounds originating from reactions of the glycidyl ethers with bisphenols, solvents, and chain stoppers. Two extracts from food-can coatings were investigated in detail. It was possible to elucidate the structures of many substances and consequently to draw conclusions about the production of the lacquers.
Berger
U
U
University of Basel, Organic Analytical Chemistry, Switzerland.
Oehme
M
M
D000085:Acetates; D001559:Benzhydryl Compounds; D002273:Carcinogens / Q000737:chemistry*; D002853:Chromatography, Liquid; D004852:Epoxy Compounds / Q000737:chemistry*; D005519:Food Preservation; D013058:Mass Spectrometry; D008970:Molecular Weight; D010647:Phenyl Ethers / Q000737:chemistry*; D012015:Reference Standards; D012996:Solutions; D012997:Solvents; D013050:Spectrometry, Fluorescence; D000098826:Bisphenol A Compounds
D000085:Acetates; D001559:Benzhydryl Compounds; D002273:Carcinogens; D004852:Epoxy Compounds; D010647:Phenyl Ethers; D012996:Solutions; D012997:Solvents; C420695:novolac glycidyl ether; C019273:bisphenol A diglycidyl ether; D000098826:Bisphenol A Compounds; C018824:ammonium acetate