Signal transduction during fertilization in the unicellular green alga, Chlamydomonas.
Sexual reproduction in the green alga, Chlamydomonas, is regulated by environmental conditions and by cell-cell interactions. After gametogenesis, flagellar adhesion between gametes triggers gamete activation, leading to cell fusion and zygote formation. Recent studies have identified new molecular events that underlie signal transduction during Chlamydomonas fertilization, including expression of a sex-determining protein, phosphorylation of a homeodomain protein, activity of a kinesin II and regulated translocation of an aurora/Ip11-like protein kinase from the cell body to the flagella.
Pan
J
J
Department of Cell Biology, University of Texas, Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-9039, USA.
Snell
W J
WJ
D000818:Animals; D064127:Aurora Kinases; D002135:Calcium-Binding Proteins / Q000378:metabolism; D002696:Chlamydomonas / Q000254:growth & development / Q000502:physiology*; D005407:Flagella / Q000378:metabolism; D005718:Gametogenesis; D018525:Germination; D018398:Homeodomain Proteins / Q000378:metabolism; D016547:Kinesins; D009124:Muscle Proteins / Q000378:metabolism; D010940:Plant Proteins / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D015398:Signal Transduction
D002135:Calcium-Binding Proteins; D018398:Homeodomain Proteins; D009124:Muscle Proteins; D010940:Plant Proteins; C074152:kinesin-II; D064127:Aurora Kinases; D017346:Protein Serine-Threonine Kinases; D016547:Kinesins