Role of human CYP3A and P-glycoprotein on the absorption of drugs.
van de Waterbeemd
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H
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000378:metabolism*; D001189:Aryl Hydrocarbon Hydroxylases; D001682:Biological Availability; D002957:Citrus; D016572:Cyclosporine / Q000493:pharmacokinetics*; D003524:Cyclosporins / Q000493:pharmacokinetics; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006801:Humans; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000502:physiology*; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism*
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D003524:Cyclosporins; D016572:Cyclosporine; D003577:Cytochrome P-450 Enzyme System; D001189:Aryl Hydrocarbon Hydroxylases; D051544:Cytochrome P-450 CYP3A; D010089:Oxidoreductases, N-Demethylating; C070272:valspodar