Amino acid residues that modulate the properties of tyrosine Y(Z) and the manganese cluster in the water oxidizing complex of photosystem II.
The catalytic site for photosynthetic water oxidation is embedded in a protein matrix consisting of nearly 30 different polypeptides. Residues from several of these polypeptides modulate the properties of the tetrameric Mn cluster and the redox-active tyrosine residue, Y(Z), that are located at the catalytic site. However, most or all of the residues that interact directly with Y(Z) and the Mn cluster appear to be contributed by the D1 polypeptide. This review summarizes our knowledge of the environments of Y(Z) and the Mn cluster as obtained from the introduction of site-directed, deletion, and other mutations into the photosystem II polypeptides of the cyanobacterium Synechocystis sp. PCC 6803 and the green alga Chlamydomonas reinhardtii.
Debus
R J
RJ
Department of Biochemistry, University of California, Riverside, CA 92521-0129, USA. debusrj@citrus.ucr.edu
D000596:Amino Acids / Q000737:chemistry*; D000818:Animals; D016825:Chlamydomonas reinhardtii / Q000235:genetics; D000458:Cyanobacteria / Q000235:genetics; D045342:Light-Harvesting Protein Complexes; D008345:Manganese / Q000737:chemistry*; D016297:Mutagenesis, Site-Directed; D009942:Organometallic Compounds / Q000737:chemistry; D010084:Oxidation-Reduction; D010788:Photosynthesis; D045322:Photosynthetic Reaction Center Complex Proteins / Q000737:chemistry* / Q000235:genetics; D045332:Photosystem II Protein Complex; D017510:Protein Folding; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D000596:Amino Acids; D045342:Light-Harvesting Protein Complexes; D009942:Organometallic Compounds; D045322:Photosynthetic Reaction Center Complex Proteins; D045332:Photosystem II Protein Complex; C083100:photosystem II, chlorophyll binding protein, CP-43; C066447:tyrosyl radical Y(D); C114979:tyrosyl radical YZ; D014867:Water; C070970:photosystem II, chlorophyll-binding protein, CP-47; D014443:Tyrosine; D008345:Manganese