title: Successful pregnancy and birth after sequential cotreatment with growth hormone and gonadotropins in a woman with panhypopituitarism: a new treatment protocol.
abstract: OBJECTIVE
  To report a successful pregnancy in a woman with panhypopituitarism who received 3 months of pretreatment with growth hormone (GH) before ovulation induction. Prior attempts at ovulation induction had failed for this patient.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Department of Endocrinology.
  
  
  METHODS
  A 32-year-old woman with panhypopituitarism and secondary infertility.
  
  
  METHODS
  GH (1 IU/day) alone for 3 months; during the next cycle, 1 IU/day of GH; 3 ampules of hMG per day during days 1-21; 1 ampule of hCG on day 21. GH was discontinued on day 35 when a pregnancy test was positive.
  
  
  METHODS
  Pregnancy and delivery.
  
  
  RESULTS
  Pregnancy and birth of a normal child after a single ovulation stimulation using GH and gonadotropins.
  
  
  CONCLUSIONS
  This case report suggests interest in a new protocol for follicular stimulation in women with hypopituitarism who are responding poorly to gonadotropin therapy.
authors: Department of Endocrinology, Centre Hospitalier Universitaire de Nancy, Vandoeuvre, France.
authors: A
authors: A
authors: Salle
authors: M
authors: M
authors: Klein
authors: V
authors: V
authors: Pascal-Vigneron
authors: B
authors: B
authors: Dousset
authors: J
authors: J
authors: Leclere
authors: G
authors: G
authors: Weryha
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D019382:Human Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D007018:Hypopituitarism / Q000150:complications / Q000188:drug therapy*; D007231:Infant, Newborn; D007247:Infertility, Female / Q000188:drug therapy* / Q000209:etiology; D007743:Labor, Obstetric; D008297:Male; D008596:Menotropins / Q000627:therapeutic use*; D011247:Pregnancy
chemical_list: D006063:Chorionic Gonadotropin; D019382:Human Growth Hormone; D008596:Menotropins