A comparison of myocardial beta-adrenoreceptor density and ligand binding affinity among selected teleost fishes.
This study quantified the cell surface beta-adrenoreceptor density and ligand binding affinity in the ventricular tissue of seven teleost species; skipjack tuna (Katsowonus pelamis), yellowfin tuna (Thunnus albacares), Pacific mackerel (Scomber japonicus), mahimahi (dolphin fish; Coryphaena hippurus), sockeye salmon (Oncorhynchus nerka), rainbow trout (Oncorhynchus mykiss) and an Antarctic nototheniid (Trematomus bernacchii). Beta-Adrenoreceptor density varied by almost fourfold among these species, being highest for the athletic fish: sockeye salmon among the salmonids and skipjack tuna among the scombrids. Beta-Adrenoreceptor density was lowest for the Antarctic icefish. Beta-Adrenoreceptor binding affinity varied by almost threefold. We conclude that there is a significant species-specific variability in myocardial beta-adrenoreceptor density and binding affinity and these interspecific differences cannot be attributed to temperature even though intraspecifically cold temperature can stimulate an increase in myocardial beta-adrenoreceptor density. Instead, we suggest that interspecifically myocardial beta-adrenoreceptor density is highest in fish that inhabit tropical water.
Olsson
H I
HI
Zoophysiology Department, University of Goteborg, Sweden.
Yee
N
N
Shiels
H A
HA
Brauner
C
C
Farrell
A P
AP
D000818:Animals; D001667:Binding, Competitive; D005399:Fishes / Q000378:metabolism*; D008024:Ligands; D009206:Myocardium / Q000378:metabolism*; D017686:Oncorhynchus mykiss; D010473:Perciformes; D011943:Receptors, Adrenergic, beta / Q000378:metabolism*; D012474:Salmon; D014413:Tuna
D008024:Ligands; D011943:Receptors, Adrenergic, beta