Ultrafast scan magnetic resonance in prenatal diagnosis.
OBJECTIVE
To determine whether magnetic resonance (MR) can give additional information in prenatal diagnosis of congenital anomalies, when the ultrasound (US) analysis is not conclusive.


METHODS
Ultrafast MR scanning examined 39 pregnant women with 41 fetuses in whom US was suspicious of fetal congenital abnormalities. Two techniques were used namely (1) HASTE inversion recovery sequence and (2) FISP 2D.


RESULTS
Thirty-nine patients with 41 fetuses were referred for MR because of an equivocal US with regard to brain, spine, skeletal and miscellaneous anomalies. In 1 twin pregnancy, 1 co-twin has not been examined with MRI because of its demise. In 22 of them, additional information was obtained by MR. In 9 the MR was confirmative with the US examination. Four were false negative, comparing with the postnatal diagnosis. Three failed because of maternal claustrophobia and in 2 a diagnosis could not be made. From the 40 fetuses in this study, 38 were examined postnatally by MR, US, plain X-ray or autopsy was performed to confirm the prenatal diagnosis.


CONCLUSIONS
The use of MRI in obstetrics has been limited, until recently. With fast MRI sequences it is not necessary to sedate the fetus. It is advisable in cases where US is equivocal concerning congenital anomalies of the fetus to use MR with fast or ultrafast scan technique, especially when the central nervous system is concerned.
Wagenvoort
A M
AM
Department of Obstetrics and Gynecology, Division of Prenatal Diagnosis and Therapy, University Hospital 'Vrije Universiteit', Amsterdam, The Netherlands.
Bekker
M N
MN
Go
A T
AT
Vandenbussche
F P
FP
van Buchem
M A
MA
Valk
J
J
van Vugt
J M
JM
D001921:Brain / Q000002:abnormalities*; D001927:Brain Diseases / Q000151:congenital / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011247:Pregnancy; D013122:Spinal Diseases / Q000151:congenital / Q000000981:diagnostic imaging / Q000473:pathology; D013131:Spine / Q000002:abnormalities*; D013997:Time Factors; D016216:Ultrasonography, Prenatal / Q000379:methods*