title: Granulocytic sarcoma with breast and skin presentation: a report of a case successfully treated by local radiation and systemic chemotherapy.
abstract: Granulocytic sarcoma (GS) is a rare extramedullary tumor composed of immature myeloid cells. It is usually associated with leukemia or other myeloproliferative disorders, but can also occur without overt hematologic disease, i.e. in patients with a normal bone marrow and no history of acute myelogenous leukemia. This primary extramedullary lesion may indeed represent a diagnostic and therapeutic dilemma for both the hematopathologist and oncologist. We describe a case of GS diagnosed in a nonleukemic patient and review the literature regarding the pathologic features and treatment of this condition.
authors: Dipartimento di Biotecnologie Cellulari ed Ematologia, Università La Sapienza, Roma, Italia.
authors: M
authors: M
authors: Breccia
authors: M C
authors: MC
authors: Petti
authors: G
authors: G
authors: Fraternali-Orcioni
authors: B
authors: B
authors: Monarca
authors: R
authors: R
authors: Latagliata
authors: G M
authors: GM
authors: D'Elia
authors: F
authors: F
authors: Mandelli
authors: S A
authors: SA
authors: Pileri
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D007938:Leukemia / Q000175:diagnosis* / Q000473:pathology* / Q000628:therapy; D007951:Leukemia, Myeloid / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D018714:Radiotherapy, Adjuvant; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents