Propolis from the Mediterranean region: chemical composition and antimicrobial activity.
The chemical composition of propolis from Bulgaria, Turkey, Greece and Algeria was investigated by GC-MS. All of them contained mainly flavonoids and esters of caffeic and ferulic acids, which indicated that their main source are buds of poplars of the taxonomic section Aegieros. Some Turkish samples contained a low percent of diterpenic acids, while in Algerian samples significant amounts of a hydroxyditerpenic acid (M=322, its structure not determined by its MS) were found. All samples showed significant antibacterial and weak to moderate antifungal activity.
Velikova
M
M
Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia.
Bankova
V
V
Sorkun
K
K
Houcine
S
S
Tsvetkova
I
I
Kujumgiev
A
A
D000462:Algeria; D000818:Animals; D000900:Anti-Bacterial Agents; D001516:Bees; D002031:Bulgaria; D002241:Carbohydrates / Q000032:analysis; D002264:Carboxylic Acids / Q000032:analysis; D032462:Cycadopsida; D004224:Diterpenes / Q000032:analysis; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development; D004952:Esters / Q000032:analysis; D005227:Fatty Acids / Q000032:analysis; D005419:Flavonoids / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry; D006115:Greece; D019083:Mediterranean Region; D011429:Propolis / Q000737:chemistry* / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development; D014197:Trees; D014421:Turkey
D000900:Anti-Bacterial Agents; D002241:Carbohydrates; D002264:Carboxylic Acids; D004224:Diterpenes; D004952:Esters; D005227:Fatty Acids; D005419:Flavonoids; D011429:Propolis