Recognition of another member of the malignant catarrhal fever virus group: an endemic gammaherpesvirus in domestic goats.
A novel gammaherpesvirus in goats that is herein tentatively designated as caprine herpesvirus-2 was identified based on the sequence of a fragment from the herpesvirus DNA polymerase gene. Sequence alignment analysis revealed that the virus sequence isolated from goats was 67% identical to the homologous sequence from alcelaphine herpesvirus-1, 71% identical to ovine herpesvirus-2 and 73% identical to a recently recognized herpesvirus causing malignant catarrhal fever in white-tailed deer. Combined serological and PCR-survey data demonstrated that this virus is endemic in goats and its transmission pattern may be similar to that of ovine herpesvirus-2 in sheep.
Li
Hong
H
Animal Diseases Research Unit, USDA-ARS1 and Department of Veterinary Microbiology and Pathology2, Washington State University, 3003 ADBF, Pullman, WA 99164-6630, USA.
Keller
Janice
J
Animal Diseases Research Unit, USDA-ARS1 and Department of Veterinary Microbiology and Pathology2, Washington State University, 3003 ADBF, Pullman, WA 99164-6630, USA.
Knowles
Donald P
DP
Animal Diseases Research Unit, USDA-ARS1 and Department of Veterinary Microbiology and Pathology2, Washington State University, 3003 ADBF, Pullman, WA 99164-6630, USA.
Crawford
Timothy B
TB
Animal Diseases Research Unit, USDA-ARS1 and Department of Veterinary Microbiology and Pathology2, Washington State University, 3003 ADBF, Pullman, WA 99164-6630, USA.
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D016384:Consensus Sequence; D004196:Disease Outbreaks / Q000662:veterinary*; D018142:Gammaherpesvirinae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D016679:Genome, Viral; D015511:Goat Diseases / Q000453:epidemiology / Q000821:virology*; D006041:Goats / Q000821:virology*; D008304:Malignant Catarrh / Q000453:epidemiology / Q000821:virology*; D008969:Molecular Sequence Data; D015995:Prevalence; D016415:Sequence Alignment