L1 effects on reactive oxygen (ROS) and nitrogen species (RNS) release, hemoglobin oxidation, low molecular weight antioxidants, and antioxidant enzyme activities in red and white blood cells of thalassemic patients.
Korkina
L
L
Department of Molecular Biology, Russian State Medical University, 1 Ostrovityanova St., 117513 Moscow, Russia. korkin@aha.ru
De Luca
C
C
Deeva
I
I
Perrotta
S
S
Nobili
B
B
Passi
S
S
Puddu
P
P
D000975:Antioxidants / Q000378:metabolism; D000077543:Deferiprone; D003676:Deferoxamine / Q000494:pharmacology* / Q000627:therapeutic use; D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007502:Iron Chelating Agents / Q000494:pharmacology* / Q000627:therapeutic use; D007962:Leukocytes / Q000187:drug effects* / Q000378:metabolism*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000378:metabolism; D011728:Pyridones / Q000494:pharmacology* / Q000627:therapeutic use; D017086:beta-Thalassemia / Q000097:blood* / Q000188:drug therapy*
D000975:Antioxidants; D006454:Hemoglobins; D007502:Iron Chelating Agents; D011728:Pyridones; D000077543:Deferiprone; D003676:Deferoxamine; D010100:Oxygen