title: Blood groups and their function.
abstract: The function(s) assigned to red blood cell membrane components is based on an observed effect in the red cells that lack the component, comparison of the protein sequence (predicted from the nucleotide sequence of the gene) to proteins of known function, and extrapolation of function of the component in other cells. The functions are varied and include membrane structure, transport, receptor, adhesion, enzyme activity, complement components, complement regulation and glycocalyx formation. Several components have more than one function.
authors: New York Blood Center, 310 East 67th Street, New York, New York 10021, USA.
authors: M E
authors: ME
authors: Reid
authors: V
authors: V
authors: Yahalom
mesh_terms: D001692:Biological Transport; D001789:Blood Group Antigens / Q000235:genetics / Q000502:physiology*; D002352:Carrier Proteins; D002448:Cell Adhesion; D003165:Complement System Proteins; D004798:Enzymes / Q000097:blood; D004910:Erythrocyte Membrane / Q000737:chemistry / Q000648:ultrastructure; D019276:Glycocalyx / Q000378:metabolism; D006801:Humans; D011956:Receptors, Cell Surface
chemical_list: D001789:Blood Group Antigens; D002352:Carrier Proteins; D004798:Enzymes; D011956:Receptors, Cell Surface; D003165:Complement System Proteins