Inhibition of transforming growth factor-beta 1 gene overexpression as a strategy to prevent fibrosis.
Gambaro
G
G
Department of Medical and Surgical Sciences, Division of Nephrology, University of Padova, Italy. giga@uxl.unipd.it
Weigert
C
C
Ceol
M
M
Schleicher
E D
ED
D000818:Animals; D002352:Carrier Proteins / Q000096:biosynthesis; D003864:Depression, Chemical; D003928:Diabetic Nephropathies / Q000188:drug therapy / Q000378:metabolism / Q000628:therapy; D015314:Dialysis Solutions / Q000009:adverse effects; D004789:Enzyme Activation / Q000187:drug effects; D016326:Extracellular Matrix Proteins / Q000096:biosynthesis / Q000187:drug effects; D005355:Fibrosis / Q000517:prevention & control*; D005786:Gene Expression Regulation / Q000187:drug effects*; D005920:Glomerular Mesangium / Q000187:drug effects / Q000378:metabolism; D005947:Glucose / Q000009:adverse effects; D017127:Glycation End Products, Advanced / Q000009:adverse effects / Q000494:pharmacology; D006025:Glycosaminoglycans / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D007527:Isoenzymes / Q000378:metabolism; D053779:Latent TGF-beta Binding Proteins; D016328:NF-kappa B / Q000378:metabolism; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects; D010537:Peritoneum / Q000187:drug effects / Q000473:pathology*; D010538:Peritonitis / Q000209:etiology / Q000473:pathology; D011493:Protein Kinase C / Q000378:metabolism; D012333:RNA, Messenger / Q000096:biosynthesis; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D013997:Time Factors; D016212:Transforming Growth Factor beta / Q000096:biosynthesis* / Q000235:genetics
D002352:Carrier Proteins; D015314:Dialysis Solutions; D016326:Extracellular Matrix Proteins; D017127:Glycation End Products, Advanced; D006025:Glycosaminoglycans; D047908:Intracellular Signaling Peptides and Proteins; D007527:Isoenzymes; D053779:Latent TGF-beta Binding Proteins; D016328:NF-kappa B; D012333:RNA, Messenger; D016212:Transforming Growth Factor beta; D011493:Protein Kinase C; D005947:Glucose; D013755:Tetradecanoylphorbol Acetate