title: Cytochrome oxidase activity in rat retinal ganglion cells during postnatal development.
abstract: In this study, the metabolic activity of rat retinal ganglion cells during postnatal development has been examined in vivo using cytochrome oxidase histochemistry. The intensity of staining was measured by optical densitometry. The activity of cytochrome oxidase in retinal ganglion cells progressively increased from postnatal day 0 (P0) and reached a peak during the second week of postnatal development (P10-P14) and declined thereafter. Our data show that the increased levels of cytochrome oxidase seen in developing retinal ganglion cells occur at the same time, when neuronal maturity and synaptogenesis reach their peaks.
authors: Department of Neurophysiology, National Institute of Mental Health and Neurosciences, Hosur Road, 560029, Bangalore, India.
authors: Govindaiah
authors: B S
authors: BS
authors: Shankaranarayana Rao
authors: Y
authors: Y
authors: Ramamohan
authors: Y K
authors: YK
authors: Singh
authors: N K
authors: NK
authors: Dhingra
authors: T R
authors: TR
authors: Raju
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development / Q000378:metabolism*; D003576:Electron Transport Complex IV / Q000378:metabolism*; D006651:Histocytochemistry; D051381:Rats; D017208:Rats, Wistar; D012165:Retinal Ganglion Cells / Q000201:enzymology*; D013194:Staining and Labeling
chemical_list: D003576:Electron Transport Complex IV