Use of topical cyclosporin for conjunctival manifestations of actinic prurigo.
OBJECTIVE
To report the successful treatment of conjunctival manifestations of actinic prurigo with topical cyclosporin.


METHODS
A 12-year-old female with extensive limbal lesions and chronic conjunctivitis secondary to actinic prurigo was treated with topical cyclosporin, and a rapid clinical response was observed.


RESULTS
The patient had the limbal lesions surgically excised. The lesions completely recurred over the first 2 postoperative months. Treatment with topical steroids and vitamin A ointment was unsuccessful. The patient was then treated with cyclosporine 2% drops and a dramatic improvement occurred. Over a 3-month period, the lesions completely resolved.


CONCLUSIONS
Cyclosporine eyedrops may be an effective treatment for the conjunctival manifestations of actinic prurigo.
McCoombes
J A
JA
Division of Ophthalmology, University of Queensland, Princess Alexandra Hospital, Brisbane, Australia.
Hirst
L W
LW
Green
W R
WR
D000287:Administration, Topical; D002648:Child; D003231:Conjunctivitis / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D016572:Cyclosporine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D009883:Ophthalmic Solutions; D010787:Photosensitivity Disorders / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D011536:Prurigo / Q000150:complications / Q000188:drug therapy* / Q000473:pathology
D007166:Immunosuppressive Agents; D009883:Ophthalmic Solutions; D016572:Cyclosporine