title: The auditory threshold in a school-age population is related to iodine intake and thyroid function.
abstract: The aim of this study was to determine the relationship between auditory capacity and urinary iodine, taking into account thyroid volume and function, in a population of school-age children. Audiometry was carried out in 150 children (ages 6-14 years), together with measurements of thyroid volume, thyrotropin (TSH), free T3, free T4, thyroglobulin, antiperoxidase and anti-TSH receptor antibodies, as well as iodine in a casual urine sample. Children with a TSH >5 microU/mL were excluded from the study. In the children with palpable goiter, there was an inverse relation between the auditory threshold at all frequencies and ioduria. Children with thyroglobulin values >10 ng/mL had a higher auditory threshold at all frequencies. In the children with palpable goiter and ioduria <100 microg/L, the levels of thyroglobulin and ioduria and the age accounted for 75% of the decibel (dB) variance at 2000 (Hertz), with similar results at other frequencies. The children with a thyroid sized at the >95th percentile had an odds ratio of 3.86 (95% confidence interval: 2.59-5.10) of having a threshold >20 dB. The results warn that iodine prophylaxis is needed to prevent not only goiter but also other iodine-deficiency disorders, such as involvement of the auditory threshold in school-age children.
authors: Endocrinology and Nutrition Service, Civil Hospital, Carlos Haya Hospital Complex, Malaga, Spain. soriguer@arrakis.es
authors: F
authors: F
authors: Soriguer
authors: M C
authors: MC
authors: Millón
authors: R
authors: R
authors: Muñoz
authors: I
authors: I
authors: Mancha
authors: J P
authors: JP
authors: López Siguero
authors: M J
authors: MJ
authors: Martinez Aedo
authors: R
authors: R
authors: Gómez-Huelga
authors: M J
authors: MJ
authors: Garriga
authors: G
authors: G
authors: Rojo-Martinez
authors: I
authors: I
authors: Esteva
authors: F J
authors: FJ
authors: Tinahones
mesh_terms: D000293:Adolescent; D001309:Auditory Threshold / Q000502:physiology*; D001844:Bone Conduction / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D003638:Deafness / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006042:Goiter / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology*; D006320:Hearing Tests; D006801:Humans; D007455:Iodine / Q000008:administration & dosage* / Q000652:urine; D008297:Male; D013961:Thyroid Gland / Q000502:physiology*
chemical_list: D007455:Iodine