A silaproline-containing dipeptide.
The silaproline-containing dipeptide N-(3, 3-dimethyl-1-pivaloyl-1-aza-3-sila-5-cyclopentylcarbonyl)-L- alanine isopropylamide, C(17)H(33)N(3)O(3)Si, has two independent molecules in the asymmetric unit and each adopts a beta-II folded conformation, where the amide on the terminal C interacts intramolecularly with the pivaloyl O atom. The five-membered silaproline ring is C(beta)-puckered, an infrequent conformation for the homologous proline ring.
Vivet
B
B
Laboratoire des Aminoacides, Peptides et Protéines, UMR-CNRS 5810, Universités Montpellier I et II, UM II, CC19, 34095 Montpellier CEDEX 05, France.
Cavelier
F
F
Martinez
J
J
Didierjean
C
C
Marraud
M
M
Aubry
A
A
D018360:Crystallography, X-Ray; D004151:Dipeptides / Q000737:chemistry*; D017646:Organosilicon Compounds / Q000737:chemistry*; D017433:Protein Structure, Secondary
D004151:Dipeptides; C420701:N-(3,3-dimethyl-1-pivaloyl-1-aza-3-sila-5-cyclopentylcarbonyl)alanine isopropylamide; D017646:Organosilicon Compounds