Perspectives on modern orthopaedics: use of Adcon-L for epidural scar prevention.
Adcon-L is a biodegradable gel matrix that was recently approved by the Food and Drug Administration for use during single-level posterior lumbar laminectomy or laminotomy procedures. Experimental and clinical studies have suggested that the use of this product will decrease postoperative epidural scarring. However, the relationship between epidural fibrosis and patient outcome remains unclear. If the treating surgeon is of the opinion that there is a need to reduce epidural scar, the use of this product appears worthwhile. However, further studies are needed to evaluate clinical outcome and justify the use of this product on a routine basis.
Fischgrund
J S
JS
William Beaumont Hospital, Royal Oak, Mich., USA.
D000818:Animals; D002921:Cicatrix / Q000517:prevention & control*; D005782:Gels / Q000627:therapeutic use*; D006801:Humans; D007796:Laminectomy; D009930:Organic Chemicals
C104199:ADCON-L; D005782:Gels; D009930:Organic Chemicals