Free radical formation and oxyhemoglobin oxidation in beta-thalassemic red blood cells in the presence of prooxidants: effects of the free radical scavenger rutin and oral chelator L1.
Afanas'ev
I B
IB
Vitamin Research Institute, Nauchny pr. 14A, Moscow 117820, Russian Federation. iafan@aha.ru
Afanas'ev
I I
II
Deeva
I B
IB
Korkina
L G
LG
D000077543:Deferiprone; D004912:Erythrocytes / Q000378:metabolism*; D016166:Free Radical Scavengers / Q000378:metabolism / Q000494:pharmacology; D005609:Free Radicals / Q000378:metabolism*; D006801:Humans; D007502:Iron Chelating Agents / Q000378:metabolism / Q000494:pharmacology; D016877:Oxidants / Q000378:metabolism / Q000494:pharmacology; D010084:Oxidation-Reduction; D010108:Oxyhemoglobins / Q000378:metabolism*; D011728:Pyridones / Q000378:metabolism / Q000494:pharmacology; D012431:Rutin / Q000378:metabolism / Q000494:pharmacology; D017086:beta-Thalassemia / Q000097:blood* / Q000188:drug therapy
D016166:Free Radical Scavengers; D005609:Free Radicals; D007502:Iron Chelating Agents; D016877:Oxidants; D010108:Oxyhemoglobins; D011728:Pyridones; D000077543:Deferiprone; D012431:Rutin