Molecular modeling of buspirone-serotonin receptor interactions.
Modern concepts of buspirone activity as an anxiolytic drug are reviewed. Particular attention is focused on the molecular aspects of buspirone interactions in the phases that simulate cellular environment. Three-dimensional models of buspirone-serotonin receptor complexes are discussed as well.
Chilmonńczyk
Z
Z
Drug Institute, 30/34 Chełmska, 00-725 Warsaw, Poland.
Cybulski
J
J
Bronowska
A
A
Leś
A
A
D002065:Buspirone / Q000494:pharmacology*; D008958:Models, Molecular; D011985:Receptors, Serotonin / Q000187:drug effects*; D012702:Serotonin Antagonists / Q000494:pharmacology*
D011985:Receptors, Serotonin; D012702:Serotonin Antagonists; D002065:Buspirone