title: Granulomatous anterior uveitis in a patient with CREST syndrome.
abstract: The CREST syndrome is a variant form of progressive systemic sclerosis. Apart from the occurrence of keratoconjunctivitis sicca, other types of ocular involvement associated with this variant are quite rare. We present the case of a 73-year-old woman with the CREST variant of progressive systemic sclerosis who developed unilateral granulomatous anterior uveitis. Systemic and laboratory testing failed to suggest evidence for any other associated systemic disease as a possible cause of the granulomatous uveitis. The inflammation was successfully controlled with topical steroids and mydriatics. While a small number of cases of uveitis have been reported in other variant forms of progressive systemic sclerosis, to date there have been no descriptions of uveitis associated with the CREST syndrome.
authors: Department of Ophthalmology, Faculty of Medicine, Baskent University, Ankara, Turkey. choroid@excite.com
authors: A
authors: A
authors: Akman
authors: Y A
authors: YA
authors: Akova
authors: E
authors: E
authors: Yücel
authors: P
authors: P
authors: Aydin
mesh_terms: D000287:Administration, Topical; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D017675:CREST Syndrome / Q000150:complications*; D003519:Cyclopentolate / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids; D006099:Granuloma / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D009184:Mydriatics / Q000627:therapeutic use; D009883:Ophthalmic Solutions / Q000627:therapeutic use; D011239:Prednisolone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014606:Uveitis, Anterior / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D009184:Mydriatics; D009883:Ophthalmic Solutions; C009935:prednisolone acetate; D011239:Prednisolone; D003519:Cyclopentolate