title: Application of a channel biosensor for toxicity measurements in cultured Alexandrium tamarense.
abstract: The purpose of this study is to examine the toxicity of Alexandrium tamarense strains using a channel biosensor. With this biosensor, we were able to measure very small quantities of PSP toxin contained within an individual plankton cell. However, measurement of at least 100 cells is more desirable for increasing the sensitivity of the assay. Therefore, in the near future, the proposed biosensor system may be used for monitoring the STX (saxitoxin) produced by a few naturally toxic phytoplankton, and also measuring small amounts of toxin in shellfish.
authors: Department of Life Science, College of Natural Sciences, Hanyang University, Seoul 133-791, Korea.
authors: H O
authors: HO
authors: Lee
authors: B S
authors: BS
authors: Cheun
authors: J S
authors: JS
authors: Yoo
authors: E
authors: E
authors: Watanabe
authors: M S
authors: MS
authors: Han
mesh_terms: D001681:Biological Assay / Q000379:methods; D015374:Biosensing Techniques; D010839:Phytoplankton / Q000737:chemistry*; D012530:Saxitoxin / Q000633:toxicity*; D015222:Sodium Channels / Q000187:drug effects* / Q000502:physiology; D018675:Toxicity Tests / Q000379:methods
chemical_list: D015222:Sodium Channels; D012530:Saxitoxin