title: Menstrual cycle irregularity and the incidence of nausea and vomiting after laparoscopy.
abstract: Gender is an important risk factor for postoperative nausea and vomiting. Menstrual cycle phase has also been implicated as a further variable in female patients. It is not clear whether a history of an irregular menstrual cycle is a significant variable and studies to date have not examined this. The influence of an irregular menstrual cycle on nausea and vomiting after laparoscopy was evaluated in a blinded, prospective, observational study. One hundred and fifty-nine patients scheduled for laparoscopy and dye investigation were included. Anaesthetic technique and postoperative analgesia were standardised. In comparison with patients who had a regular cycle, an irregular menstrual cycle increased the incidence of nausea or vomiting from 20.5% to 40.5% (absolute difference 20%; 95% CI 0.03-0.37, p = 0.01). Other variables were similar between the groups. An irregular menstrual cycle appears to increase the risk of postoperative nausea and vomiting.
authors: Department of Anaesthesia, Rotunda Hospital, Parnell Square, Dublin 1, Ireland.
authors: D
authors: D
authors: Harmon
authors: P
authors: P
authors: O'Connor
authors: O
authors: O
authors: Gleasa
authors: J
authors: J
authors: Gardiner
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects*; D008597:Menstrual Cycle / Q000502:physiology; D008599:Menstruation Disturbances / Q000150:complications*; D020250:Postoperative Nausea and Vomiting / Q000209:etiology*; D011446:Prospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric