title: Silent hydronephrosis/pyonephrosis due to upper urinary tract calculi in spinal cord injury patients.
abstract: METHODS
  A study of four patients with spinal cord injury (SCI) in whom a diagnosis of hydronephrosis or pyonephrosis was delayed since these patients did not manifest the traditional signs and symptoms.
  
  
  OBJECTIVE
  To learn from these cases as to what steps should be taken to prevent any delay in the diagnosis and treatment of hydronephrosis/pyonephrosis in SCI patients.
  
  
  METHODS
  Regional Spinal Injuries Centre, Southport, UK.
  
  
  METHODS
  A retrospective review of cases of hydronephrosis or pyonephrosis due to renal/ ureteric calculus in SCI patients between 1994 and 1999, in whom there was a delay in diagnosis.
  
  
  RESULTS
  A T-5 paraplegic patient had two episodes of urinary tract infection (UTI) which were successfully treated with antibiotics. When he developed UTI again, an intravenous urography (IVU) was performed. The IVU revealed a non-visualised kidney and a renal pelvic calculus. In a T-6 paraplegic patient, the classical symptom of flank pain was absent, and the symptoms of sweating and increased spasms were attributed to a syrinx. A routine IVU showed non-visualisation of the left kidney with a stone impacted in the pelviureteric junction. In two tetraplegic patients, an obstructed kidney became infected, and there was a delay in the diagnosis of pyonephrosis. The clinician's attention was focused on a co-existent, serious, infective pathology elsewhere. The primary focus of sepsis was chest infection in one patient and a deep pressure sore in the other. The former patient succumbed to chest infection and autopsy revealed pyonephrosis with an abscess between the left kidney and left hemidiaphragm and xanthogranulomatous inflammation of perinephric fatty tissue. In the latter patient, an abdominal X-ray did not reveal any calculus but computerised axial tomography showed the presence of renal and ureteric calculi.
  
  
  CONCLUSIONS
  The symptoms of hydronephrosis may be bizarre and non-specific in SCI patients. The symptoms include feeling unwell, abdominal discomfort, increased spasms, and autonomic dysreflexia. Physicians should be aware of the serious import of these symptoms in SCI patients.
authors: Regional Spinal Injuries Centre, District General Hospital, Southport, Merseyside, UK.
authors: S
authors: S
authors: Vaidyanathan
authors: G
authors: G
authors: Singh
authors: B M
authors: BM
authors: Soni
authors: P
authors: P
authors: Hughes
authors: J W
authors: JW
authors: Watt
authors: S
authors: S
authors: Dundas
authors: P
authors: P
authors: Sett
authors: K F
authors: KF
authors: Parsons
mesh_terms: D000328:Adult; D017809:Fatal Outcome; D006801:Humans; D006869:Hydronephrosis / Q000175:diagnosis / Q000209:etiology*; D007668:Kidney / Q000473:pathology; D007669:Kidney Calculi / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011704:Pyelonephritis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D012189:Retrospective Studies; D013119:Spinal Cord Injuries / Q000150:complications*; D014057:Tomography, X-Ray Computed; D014514:Ureteral Calculi / Q000150:complications* / Q000175:diagnosis; D014567:Urography