Drug-resistant parasites and aggregated infection--early-season dynamics.
We investigate the effect of spatial aggregation in the infection dynamics of nematode parasites in ruminants. We show that a high degree of spatial aggregation is likely to lead to a dramatically enhanced rate of invasion by drug-resistant strains.
Cornell
S J
SJ
Department of Zoology, University of Cambridge, UK. cornell@zoo.cam.ac.uk
Isham
V S
VS
Grenfell
B T
BT
D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology*; D004351:Drug Resistance / Q000235:genetics; D005260:Female; D006801:Humans; D008297:Male; D008433:Mathematics; D008954:Models, Biological; D009348:Nematoda / Q000187:drug effects / Q000235:genetics; D009349:Nematode Infections / Q000188:drug therapy* / Q000469:parasitology* / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy / Q000469:parasitology
D000871:Anthelmintics