title: Calcium pyrophosphate dihydrate crystal deposition disease: imaging perspectives.
abstract: Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is widespread in elderly persons and has various clinical presentations that can be confounding to clinicians. It is characterized by acute, subacute, or chronic joint inflammation and deposition of CPPD crystals in hyaline cartilage, fibrocartilage, and other soft tissue structures. We have learned a great deal about imaging findings of CPPD crystal deposition disease. New facts about the disorder and clues to radiologic diagnosis continue to be revealed. This article will provide a review of imaging characteristics of this disease with emphasis on some recent findings. The nomenclature, epidemiology, classification, and pathophysiology will be explained. A discussion of the clinical manifestations and treatment will be followed by a review of the characteristic imaging features.
authors: University of California San Francisco, USA.
authors: L S
authors: LS
authors: Steinbach
authors: D
authors: D
authors: Resnick
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002356:Cartilage / Q000000981:diagnostic imaging; D002805:Chondrocalcinosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003460:Crystallization; D003937:Diagnosis, Differential; D005260:Female; D006621:Hip Joint / Q000000981:diagnostic imaging; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000000981:diagnostic imaging; D012785:Shoulder Joint / Q000000981:diagnostic imaging; D013131:Spine / Q000000981:diagnostic imaging; D013583:Synovial Membrane / Q000000981:diagnostic imaging; D013710:Tendons / Q000000981:diagnostic imaging; D009626:Terminology as Topic; D014057:Tomography, X-Ray Computed; D014955:Wrist Joint / Q000000981:diagnostic imaging