title: Malfunction of a Hancock bioprosthesis in the mitral position 24 years after initial implantation.
abstract: OBJECTIVE
  Although many types of cardiac bioprosthetic valves are currently available, the major disadvantage of their use is limited durability due to progressive structural valve deterioration. Few such valves function beyond 20 years.
  
  
  METHODS
  A 61-year-old man was admitted urgently to our institute with acute mitral insufficiency, 24 years after undergoing mitral valve replacement with a 25-mm standard Hancock porcine bioprosthesis for mitral stenosis.
  
  
  RESULTS
  Mitral valve reoperation was performed successfully with a mechanical valve. The explanted bioprosthesis showed leaflet perforations and a commissural tear, moderate calcification on the commissures, and pannus overgrowth.
  
  
  CONCLUSIONS
  The findings in this case suggest that individual patient variables, as well as the design and the construction of the valve are major determining factors in the rate of valve failure.
authors: Department of Cardiovascular Surgery, The Heart Institute of Japan, Tokyo Women's Medical University.
authors: H
authors: H
authors: Niinami
authors: Y
authors: Y
authors: Naito
authors: H
authors: H
authors: Koyanagi
authors: H
authors: H
authors: Nagashima
authors: H
authors: H
authors: Kasanuki
mesh_terms: D001705:Bioprosthesis; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D008946:Mitral Valve Stenosis / Q000601:surgery; D011475:Prosthesis Failure; D013997:Time Factors