Form of the worm: genetics of epidermal morphogenesis in C. elegans.
The development of the epidermis of the nematode worm Caenorhabditis elegans illustrates many common processes of epithelial morphogenesis. In the worm, these morphogenetic movements have been described with single-cell resolution, and the roles of individual cells have been probed in laser killing experiments. Genetic dissection is yielding insights into the molecular mechanisms of these complex morphogenetic processes.
Chin-Sang
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Dept of Biology, Sinsheimer Laboratories, University of California, Santa Cruz, CA 95064, USA. chinsang@biology.ucsc.edu
Chisholm
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D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics* / Q000254:growth & development; D009024:Morphogenesis