Pleural effusion cytology in a case of cytophagic histiocytic panniculitis (subcutaneous panniculitic T-cell lymphoma). A case report.
BACKGROUND
Cytophagic histiocytic panniculitis (CHP) presents with subcutaneous panniculitis associated with hemophagocytic syndrome. Many cases of CHP are now being classified as a natural disease progression of subcutaneous panniculitic T-cell lymphoma (SPTL). There have been no cytologic reports dealing with pleural aspirates in cases of CHP or SPTL.


METHODS
A pleural aspirate obtained from a 19-year-old female revealed lymphoma cells and hemophagocytic histiocytes. A skin biopsy specimen showed the presence of CD8-positive lymphoma cells in fat lobules associated with cytologically benign histiocytes with erythrophagocytosis and lymphophagocytosis.


CONCLUSIONS
Hemophagocytic histiocytes were seen in the pleural effusion from a patient with SPTL.
Moriki
T
T
Departments of Clinical Laboratory and Pathology, Kochi Medical School and Kochi Medical School Hospital, Nankoku, Kochi, Japan.
Wada
M
M
Takahashi
T
T
Ueda
S
S
Miyazaki
E
E
D000328:Adult; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D006644:Histiocytes / Q000473:pathology; D015614:Histiocytosis / Q000150:complications / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D016399:Lymphoma, T-Cell / Q000150:complications / Q000473:pathology*; D015434:Panniculitis / Q000150:complications / Q000473:pathology*; D010587:Phagocytosis; D010996:Pleural Effusion / Q000150:complications / Q000473:pathology*; D012867:Skin / Q000473:pathology