title: CT appearance of hepatic parenchymal changes after percutaneous microwave coagulation therapy for hepatocellular carcinoma.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the changes in the CT appearance of the hepatic parenchyma surrounding the necrotic area in the early period after percutaneous microwave coagulation therapy (PMCT) for hepatocellular carcinoma (HCC).
  
  
  METHODS
  We reviewed enhanced CT scans obtained before and within 2 weeks, at 1 month, and at 3 months after PMCT of 61 lesions in 47 patients with HCC.
  
  
  RESULTS
  On dynamic CT, early enhancement of the hepatic parenchyma around the treated area was a frequent finding within 1 (87%) or 2 (68%) weeks after PMCT, but such enhancement disappeared on follow-up. Arterioportal shunts were also demonstrated by enhanced CT after treatment (21% at < or =2 weeks), and these shunts tended to persist for >1 month.
  
  
  CONCLUSIONS
  We should evaluate the effect of PMCT by performing dynamic enhanced CT not only within 2 weeks to determine the end-point of treatment but also at 1 month or more after finishing treatment for definite assessment of tumor necrosis.
authors: Department of Medicine, Kawasaki Medical School, Kurashiki, Okayama, Japan. ohmotok@med.kawasaki-m.ac.jp
authors: K
authors: K
authors: Ohmoto
authors: M
authors: M
authors: Tsuduki
authors: T
authors: T
authors: Kunieda
authors: Y
authors: Y
authors: Mitsui
authors: S
authors: S
authors: Yamamoto
mesh_terms: D000328:Adult; D000368:Aged; D001163:Arteriovenous Anastomosis; D001707:Biopsy, Needle; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D003287:Contrast Media; D003972:Diathermy; D004567:Electrodes, Implanted; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging* / Q000473:pathology; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D008875:Middle Aged; D009336:Necrosis; D018365:Neoplasm, Residual; D011856:Radiographic Image Enhancement; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media