title: Masses of the salivary gland region in children.
abstract: BACKGROUND
  Noninflammatory masses of the salivary gland region in children are extremely rare. Therefore, very few published individual and institution-based experiences exist.
  
  
  METHODS
  Retrospective chart review from 1990 through 1997.
  
  
  METHODS
  University-based children's hospital.
  
  
  METHODS
  Patients 18 years of age or younger with a tumor in the salivary gland region. Masses of infectious origin were excluded. Hemangiomas and lymphangiomas were tallied for relative incidences only.
  
  
  RESULTS
  Three hundred twenty-four consecutive cases of salivary gland masses were found: 192 hemangiomas (59.2%), 89 lymphangiomas (27.5%), and 43 (13.3%) solid masses. No significant difference was found between the age at presentation of the patients with benign solid tumors and the patients with malignant solid tumors (mean + SEM age, 7.2 + 0.7 years). Sixty-one percent of the masses were found in the parotid region; 18% were localized to the submandibular gland region; and the remaining 21% were located in a minor salivary gland site. The most common benign perisalivary masses were pilomatrixomas (20.9%), followed by pleomorphic adenomas (11.6%). The most common malignant masses were mucoepidermoid carcinomas (9.3%), followed by rhabdomyosarcomas (7.0%). Treatment was individualized to the disease. Twenty-two patients had adequate data for follow-up analysis (mean + SEM follow-up, 30.0 + 8.4 months). Four patients (18.2%) experienced recurrent or residual disease and were alive with disease at last follow-up, and 100% of our population demonstrated disease-specific survival at last follow-up.
  
  
  CONCLUSIONS
  Vascular lesions outnumber solid tumors of the salivary gland region. The most common salivary tumors were pleomorphic adenomas, followed by mucoepidermoid carcinomas. Although certain solid salivary masses may demonstrate locally aggressive behavior, the overall prognosis is favorable. Arch Otolaryngol Head Neck Surg. 2000;126:1435-1439
authors: Division of Otolaryngology-Head and Neck Surgery, Northwestern University Medical School, Chicago, IL USA.
authors: B G
authors: BG
authors: Bentz
authors: C A
authors: CA
authors: Hughes
authors: J P
authors: JP
authors: Lüdemann
authors: J
authors: J
authors: Maddalozzo
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D018277:Carcinoma, Mucoepidermoid / Q000473:pathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006391:Hemangioma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D008202:Lymphangioma / Q000473:pathology / Q000601:surgery*; D008297:Male; D010306:Parotid Gland / Q000473:pathology; D010307:Parotid Neoplasms / Q000473:pathology / Q000601:surgery; D018296:Pilomatrixoma / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D012208:Rhabdomyosarcoma / Q000473:pathology / Q000601:surgery*; D012468:Salivary Gland Neoplasms / Q000473:pathology / Q000601:surgery*; D012470:Salivary Glands, Minor / Q000473:pathology; D013363:Submandibular Gland / Q000473:pathology; D013365:Submandibular Gland Neoplasms / Q000473:pathology / Q000601:surgery; D013997:Time Factors