Keratosis lichenoides chronica: report of a case developing after erythroderma.
A 66-year-old male presented with keratosis lichenoides chronica after a presumed drug-induced erythroderma. After resolution of the erythroderma, slightly scaly erythematous and violaceous papules in a reticular arrangement over the trunk and limbs developed in association with hoarseness, palmoplantar keratoderma, onycholysis and subungual keratosis. Histology from a lichenoid lesion showed pseudo-epitheliomatous hyperplasia, hyperorthokeratosis, parakeratosis, dyskeratosis, neutrophil exocytosis and focal vacuolar degeneration of the basal layer of the epidermis. There was a band-like chronic inflammatory infiltrate in the upper dermis. The skin improved with prednisone 40 mg/day for 15 days, leaving atrophic hypopigmented scars. A diagnosis of keratosis lichenoides chronica was made.
Criado
P R
PR
Unit of Dermatology, Hospital do Servidor Publico Estadual de Sao Paulo, Brazil. prcriado@uol.com.br
Valente
N Y
NY
Sittart
J A
JA
Juang
J M
JM
Vasconcellos
C
C
D000368:Aged; D001707:Biopsy, Needle; D003873:Dermatitis, Exfoliative / Q000150:complications* / Q000175:diagnosis; D005500:Follow-Up Studies; D006801:Humans; D007642:Keratosis / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D008010:Lichen Planus / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D008297:Male; D011241:Prednisone / Q000008:administration & dosage
D011241:Prednisone