Hypokalaemic periodic paralysis associated with controlled thyrotoxicosis.
Familial hypokalaemic periodic paralysis is an autosomal dominant muscle disease which has been linked to point mutations in the skeletal muscle L-type calcium channel alpha 1 subunit (alpha 1 s). It consists of muscular weakness episodes due to hypokalaemia caused by intracellular shifting of potassium. We describe the case of a young man of Kurdish origin, with a history of Graves' disease, who was admitted to the emergency room with hypotonic tetraplegia associated with severe hypokalaemia.
Sabau
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Internal Medicine Department, Ospedale Civico, Lugano.
Canonica
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D000328:Adult; D013956:Antithyroid Agents / Q000627:therapeutic use; D002231:Carbimazole / Q000627:therapeutic use; D004630:Emergencies; D006111:Graves Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D020514:Hypokalemic Periodic Paralysis / Q000150:complications*; D008297:Male; D011782:Quadriplegia / Q000209:etiology; D013557:Switzerland; D014421:Turkey / Q000208:ethnology
D013956:Antithyroid Agents; D002231:Carbimazole