Single, brief exposure to a 50 Hz magnetic field does not affect the performance of an object recognition task in adult mice.
A number of studies have shown that power frequency magnetic fields may affect spatial memory functions in rodents. An experiment was performed using a spontaneous object recognition task to investigate if nonspatial working memory was similarly affected. Memory changes in adult, male C57BL/6J mice were assessed by measuring the relative time within which the animals explored familiar or novel stimulus objects. Between initial testing and retesting, the animals were exposed for 45 min to a 50 Hz magnetic field at either 7.5 microT, 75 microT or 0.75 mT. Other animals were sham-exposed with ambient fields of less than 50 nT. No significant field-dependent effects on the performance of the task were observed at any flux density (for all measures, P > 0.05). These data provide no evidence to suggest that nonspatial working memory was affected in mice by acute exposure to an intense 50 Hz magnetic field.
Sienkiewicz
Z J
ZJ
National Radiological Protection Board, Chilton, Didcot, Oxfordshire, United Kingdom. zenon.sienkiewicz@nrpb.org.uk
Bartram
R
R
Haylock
R G
RG
Saunders
R D
RD
D000818:Animals; D003118:Color Perception; D004192:Discrimination, Psychological; D004574:Electromagnetic Fields; D005106:Exploratory Behavior / Q000528:radiation effects*; D008297:Male; D008568:Memory / Q000528:radiation effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D010364:Pattern Recognition, Visual / Q000187:drug effects*