title: Acute reversible cardiomyopathy and thromboembolism after cisplatin and 5-fluorouracil chemotherapy--a case report.
abstract: Acute development of cardiomyopathy and occlusive thromboembolic events following cisplatin and 5-fluorouracil (5-FU) is rare but frequently lethal. The authors report the successful management of such an event in a 52-year-old man with squamous cell carcinoma of the soft palate. The possible pathophysiological mechanisms are discussed.
authors: Division of Cardiology, The New York Methodist Hospital, Brooklyn, New York 11215, USA.
authors: K M
authors: KM
authors: Cheriparambil
authors: H
authors: H
authors: Vasireddy
authors: A
authors: A
authors: Kuruvilla
authors: B
authors: B
authors: Gambarin
authors: M
authors: M
authors: Makan
authors: B I
authors: BI
authors: Saul
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy; D009202:Cardiomyopathies / Q000139:chemically induced*; D002945:Cisplatin / Q000009:adverse effects*; D005472:Fluorouracil / Q000009:adverse effects*; D006331:Heart Diseases / Q000139:chemically induced*; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D010157:Palatal Neoplasms / Q000188:drug therapy; D013923:Thromboembolism / Q000139:chemically induced*; D014463:Ultrasonography
chemical_list: D002945:Cisplatin; D005472:Fluorouracil