title: Successful bone marrow transplantation in a patient with Schimke immuno-osseous dysplasia.
abstract: Early death in Schimke immuno-osseous dysplasia often results from renal failure and/or cell-mediated immunodeficiency. Kidney transplants have improved renal function, but effective therapy for the immunodeficiency has not yet been reported. We describe markedly improved marrow function 2 years after bone marrow transplantation in a boy with Schimke immunoosseous dysplasia.
authors: Department of Internal Medicine, University of Michigan, Ann Arbor, 48109-0638, USA.
authors: E M
authors: EM
authors: Petty
authors: G A
authors: GA
authors: Yanik
authors: R J
authors: RJ
authors: Hutchinson
authors: B P
authors: BP
authors: Alter
authors: F C
authors: FC
authors: Schmalstieg
authors: J E
authors: JE
authors: Levine
authors: D
authors: D
authors: Ginsburg
authors: J E
authors: JE
authors: Robillard
authors: V P
authors: VP
authors: Castle
mesh_terms: D015703:Antigens, CD / Q000097:blood; D016026:Bone Marrow Transplantation; D002648:Child; D002675:Child, Preschool; D006086:Graft vs Host Disease / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007231:Infant, Newborn; D016030:Kidney Transplantation; D008231:Lymphopenia / Q000150:complications / Q000175:diagnosis; D008297:Male; D010009:Osteochondrodysplasias / Q000150:complications / Q000235:genetics* / Q000628:therapy*; D010375:Pedigree; D051437:Renal Insufficiency / Q000150:complications / Q000601:surgery; D016559:Tacrolimus / Q000627:therapeutic use
chemical_list: D015703:Antigens, CD; D007166:Immunosuppressive Agents; D016559:Tacrolimus