title: Linear atrophoderma of Moulin.
abstract: We report a typical case of linear atrophoderma of Moulin that represents a distinct clinical entity. A 17-year-old woman presented with hyperpigmented and atrophic band-like skin lesions measuring 3-5 cm in breadth on the right side of her trunk and on the right buttock, in an arrangement following the system of Blaschko's lines. The skin lesions had a normal texture and showed no signs of inflammation, lilac ring, erythema, induration, sclerosis or depigmentation. Routine laboratory data were normal. Antinuclear antibodies and anti-Scl70-antibodies were negative. Histopathologically, a moderate diffuse hyperpigmentation within the lower epidermis, a focal vacuolar degeneration of the basal layer, and a few dermal perivascular lymphocytes accompanied by signs of pigment incontinence were noted. Intravenous penicillin G was administered for 14 days in a dosage of 10 x 10(6) IU twice daily. This treatment was repeated after 3 and 9 months. No effect was noted. Linear atrophoderma of Moulin takes a chronic course without progression or regression. The disease leads to significant cosmetic impairment and this may cause emotional stress. Due to its relationship to idiopathic atrophoderma of Pierini-Pasini and linear scleroderma, treatment with intravenous penicillin was tried. In our case it had no effect.
authors: Department of Dermatology, Klinikum Kassel, Mönchebergstr. 41-43 D - 34125 Kassel Germany.
authors: R
authors: R
authors: Rompel
authors: A L
authors: AL
authors: Mischke
authors: C
authors: C
authors: Langner
authors: R
authors: R
authors: Happle
mesh_terms: D000293:Adolescent; D001284:Atrophy / Q000150:complications / Q000473:pathology; D001707:Biopsy, Needle; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D011379:Prognosis; D012594:Scleroderma, Localized / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D012720:Severity of Illness Index