[Effect of 2-methyl-4-amino-6-hydroxypyrimidine on the functional state of the body exposed to extreme conditions].
The experiments on mice showed that 2-methyl-4-amino-hydroxypyrimidine (MAHP) exhibits a pronounced immunostimulant action upon the animal organism under extremal conditions. The effect of MAHP is related to the preferential activation of immunocompetent cells responsible for the immunity.
Ismagilova
A F
AF
Institute of Organic Chemistry, Ufa Scientific Center, Russian Academy of Sciences, Bashkortostan, Russia.
Belov
A E
AE
Zarudyĭ
F S
FS
Ismagilova
L U
LU
Krivonogov
V P
VP
Khalimov
R F
RF
Tolstikov
G A
GA
Tropynina
Iu F
IuF
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D006388:Hemagglutinins / Q000032:analysis; D007103:Immobilization; D008297:Male; D051379:Mice; D011743:Pyrimidines / Q000494:pharmacology*; D012756:Sheep; D013315:Stress, Psychological / Q000276:immunology*; D013550:Swimming
C113629:2-methyl-4-amino-6-oxypyrimidine; D000276:Adjuvants, Immunologic; D006388:Hemagglutinins; D011743:Pyrimidines