title: A long-term study on seasonal changes of gametic disequilibrium between allozymes and inversions in Drosophila subobscura.
abstract: Seasonal variation (spring, early summer, late summer, and autumn) of gametic disequilibrium between gene arrangements (OST and O3+4) of the O chromosome and Lap, Pept-1, and Acph allozyme loci, located inside these inversions, has been recorded in a natural population of Drosophila subobscura during seven years over a 15-year period. The length of the study allowed us to investigate the temporal variation of the allozyme-inversion associations by statistical methods of time series analysis. Cyclic seasonal changes of allozyme-inversion associations for both Lap and Pept-1 are detected in the natural population. In both cases, the patterns of seasonal change are due to the seasonal change of frequency of Lap and Pept-1 allozymes occurring exclusively within the OST gene arrangement. In contrast, the allozyme frequencies at these loci within the O3+4 gene arrangement are stable along seasons. The patterns of temporal variation of allozyme-inversion associations for Lap and Pept-1 in the natural population are contrasted with those previously published that correspond to gene arrangements of the O chromosome and nucleotide polymorphism at the rp49 region located inside these inversions, suggesting that natural selection is operating on these allozyme-inversion associations.
authors: Departamento de Biología Fundamental, Facultad de Biología, Universidad de Santiago de Compostela, Spain. bfcazaba@usc.es
authors: C
authors: C
authors: Zapata
authors: G
authors: G
authors: Alvarez
authors: F
authors: F
authors: Rodríguez-Trelles
authors: X
authors: X
authors: Maside
mesh_terms: D000135:Acid Phosphatase / Q000235:genetics; D000818:Animals; D005075:Biological Evolution; D007446:Chromosome Inversion; D002874:Chromosome Mapping; D004330:Drosophila / Q000201:enzymology / Q000235:genetics* / Q000502:physiology; D010450:Endopeptidases / Q000235:genetics; D015321:Gene Rearrangement; D007527:Isoenzymes / Q000235:genetics*; D007931:Leucyl Aminopeptidase / Q000235:genetics; D015810:Linkage Disequilibrium; D012621:Seasons
chemical_list: D007527:Isoenzymes; D000135:Acid Phosphatase; D010450:Endopeptidases; D007931:Leucyl Aminopeptidase