Treatment of ligature-induced peri-implantitis defects by regenerative procedures. Part II: A histometric study in dogs.
The purpose of this study was to evaluate, by histometric analysis, re-osseointegration following treatment of ligature-induced peri-implantitis in dogs. Five dogs were used in this study. Their mandibular premolars (P2, P3 and P4) were first removed. After 3 additional months of healing, two titanium implants were placed on each side of the mandible. After 3 months, the abutment connection was performed and experimental peri-implantitis was induced by placing cotton ligatures in a submarginal position. Ligatures and abutments were removed after one month and the peri-implant bone defects were randomly assigned to one of the treatments: debridement, debridement plus guided-bone regeneration, debridement plus mineralized-bone graft, and debridement plus guided-bone regeneration associated with mineralized-bone graft. Five months post-treatment, the degree of bone contact with the implant surface and the bone area within the threads were measured in 12 threads, the 6 most coronal at each side of each implant. One-way analysis of variance did not reveal statistically significant differences between the treatment modalities (p > 0.05). Within the limits of the present study, it can be concluded that there is a limited possibility of re-osseointegration around implant surfaces previously exposed by ligature-induced peri-implantitis.
Machado
M A
MA
Department of Prosthesis and Periodontology, University of Campinas, Piracicaba SP, Brazil.
Stefani
C M
CM
Sallum
E A
EA
Sallum
A W
AW
Tramontina
V A
VA
Nogueira-Filho
G R
GR
Nociti Júnior
F H
FH
D000704:Analysis of Variance; D000818:Animals; D001641:Bicuspid / Q000601:surgery; D018786:Bone Substitutes / Q000627:therapeutic use; D016025:Bone Transplantation; D003646:Debridement; D000044:Dental Abutments; D003758:Dental Implantation, Endosseous / Q000009:adverse effects; D015921:Dental Implants; D004285:Dogs; D005500:Follow-Up Studies; D016557:Guided Tissue Regeneration, Periodontal / Q000295:instrumentation / Q000379:methods; D008026:Ligation / Q000009:adverse effects; D008334:Mandible / Q000473:pathology / Q000601:surgery; D008567:Membranes, Artificial; D008903:Minerals / Q000627:therapeutic use; D016348:Osseointegration; D010518:Periodontitis / Q000601:surgery*; D011138:Polytetrafluoroethylene; D011897:Random Allocation; D013499:Surface Properties; D014025:Titanium; D014081:Tooth Extraction; D014945:Wound Healing
C077540:Bio-Oss; D018786:Bone Substitutes; D015921:Dental Implants; D008567:Membranes, Artificial; D008903:Minerals; D011138:Polytetrafluoroethylene; D014025:Titanium