title: A geometrically based method for automated radiosurgery planning.
abstract: OBJECTIVE
  A geometrically based method of multiple isocenter linear accelerator radiosurgery treatment planning optimization was developed, based on a target's solid shape.
  
  
  METHODS
  Our method uses an edge detection process to determine the optimal sphere packing arrangement with which to cover the planning target. The sphere packing arrangement is converted into a radiosurgery treatment plan by substituting the isocenter locations and collimator sizes for the spheres.
  
  
  RESULTS
  This method is demonstrated on a set of 5 irregularly shaped phantom targets, as well as a set of 10 clinical example cases ranging from simple to very complex in planning difficulty. Using a prototype implementation of the method and standard dosimetric radiosurgery treatment planning tools, feasible treatment plans were developed for each target. The treatment plans generated for the phantom targets showed excellent dose conformity and acceptable dose homogeneity within the target volume. The algorithm was able to generate a radiosurgery plan conforming to the Radiation Therapy Oncology Group (RTOG) guidelines on radiosurgery for every clinical and phantom target examined.
  
  
  CONCLUSIONS
  This automated planning method can serve as a valuable tool to assist treatment planners in rapidly and consistently designing conformal multiple isocenter radiosurgery treatment plans.
authors: Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, FL, USA.
authors: T H
authors: TH
authors: Wagner
authors: T
authors: T
authors: Yi
authors: S L
authors: SL
authors: Meeks
authors: F J
authors: FJ
authors: Bova
authors: B L
authors: BL
authors: Brechner
authors: Y
authors: Y
authors: Chen
authors: J M
authors: JM
authors: Buatti
authors: W A
authors: WA
authors: Friedman
authors: K D
authors: KD
authors: Foote
authors: L G
authors: LG
authors: Bouchet
mesh_terms: D000465:Algorithms; D001932:Brain Neoplasms / Q000601:surgery*; D008577:Meningeal Neoplasms / Q000532:radiotherapy; D008579:Meningioma / Q000532:radiotherapy; D009464:Neuroma, Acoustic / Q000532:radiotherapy; D019047:Phantoms, Imaging; D016634:Radiosurgery / Q000379:methods*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D020266:Radiotherapy, Conformal / Q000379:methods*