title: Laparoscopic nephrectomy in the markedly obese living renal donor.
abstract: OBJECTIVE
  To determine whether laparoscopic living donor nephrectomy is safe and efficacious in markedly obese renal donors.
  
  
  METHODS
  From 1996 to 1999, 431 laparoscopic living donor nephrectomies were performed. The markedly obese group consisted of 41 patients with a body mass index (BMI) greater than 35. Forty-one controls with a BMI less than 30 were matched to the obese donors by sex, age, race, and date of surgery.
  
  
  RESULTS
  The markedly obese and control groups were closely matched in sex, race, age, serum creatinine level, creatinine clearance, HLA match to recipient, side of donated kidney, and experience level of the surgeons. The obese patients had a BMI range of 35.2 to 53.9 (mean 39.3), and the control patients had a BMI range of 18.4 to 29.0 (mean 24.3). Donor operations in the markedly obese were significantly longer by an average of 40 minutes. The greater intraoperative blood loss and longer extraction incision length seen in the markedly obese did not reach statistical significance. More and larger laparoscopic ports were used in the markedly obese. Obese donors were more likely to require conversion from laparoscopic nephrectomy to open nephrectomy than ideal-sized donors. The postoperative recovery of the gastrointestinal tract, hospitalization time, analgesic requirements, and total complications were equal in the two groups, although the obese donors' complications tended to be cardiopulmonary problems. The recipient graft function was equivalent between the two groups.
  
  
  CONCLUSIONS
  Laparoscopic living donor nephrectomy is more difficult to perform in the markedly obese but is associated with an equivalent donor morbidity and recipient renal outcome.
authors: Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA.
authors: S C
authors: SC
authors: Jacobs
authors: E
authors: E
authors: Cho
authors: B J
authors: BJ
authors: Dunkin
authors: S T
authors: ST
authors: Bartlett
authors: J L
authors: JL
authors: Flowers
authors: B
authors: B
authors: Jarrell
authors: S C
authors: SC
authors: Jacobs
mesh_terms: D016063:Blood Loss, Surgical / Q000706:statistics & numerical data; D015992:Body Mass Index; D001835:Body Weight; D006801:Humans; D016030:Kidney Transplantation / Q000379:methods*; D010535:Laparoscopy / Q000379:methods*; D019520:Living Donors; D009392:Nephrectomy / Q000379:methods*; D009765:Obesity / Q000150:complications* / Q000175:diagnosis; D011183:Postoperative Complications / Q000453:epidemiology