Isolated innominate artery in 22q11 microdeletion.
A patient with an isolated left innominate artery (with a right-sided cervical aortic arch) is described. This is the first report of such an anomaly associated with chromosome 22q11 microdeletion. The abnormality represents an interruption in the primitive aortic arch that is atypical for this chromosome deletion.
Duke
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C
Department of Paediatric Cardiology, Glenfield Hospital, Groby Road, Leicester, United Kingdom.
Chan
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KC
D016122:Brachiocephalic Trunk / Q000002:abnormalities*; D002872:Chromosome Deletion; D002892:Chromosomes, Human, Pair 22; D004062:DiGeorge Syndrome / Q000209:etiology* / Q000235:genetics; D017809:Fatal Outcome; D006345:Heart Septal Defects, Ventricular / Q000235:genetics; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013771:Tetralogy of Fallot / Q000150:complications / Q000235:genetics