title: Automation of X-ray crystallography.
abstract: Structure-based biological discovery is entering a new era with the development of industrialized macromolecular structure determination pipelines. Intense, highly focused X-rays from integrated synchrotron radiation beam lines combined with significant advances in protein expression, purification, and micro-crystallization automation allow for the full streamlining of the traditionally tedious and time consuming process of determining the three dimensional structures of macromolecules.
authors: Department of Molecular Biology, The Scripps Research Institute, La Jolla, California 92037, USA.
authors: E
authors: E
authors: Abola
authors: P
authors: P
authors: Kuhn
authors: T
authors: T
authors: Earnest
authors: R C
authors: RC
authors: Stevens
mesh_terms: D001331:Automation / Q000379:methods*; D003460:Crystallization; D018360:Crystallography, X-Ray / Q000379:methods*; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D013048:Specimen Handling / Q000379:methods; D017356:Synchrotrons
chemical_list: D011506:Proteins