title: The pathologist's view point. Part II --aggressive lymphomas.
abstract: OBJECTIVE
  The REAL/WHO classification constitutes a new tool for the better understanding and treatment of malignant lymphomas. The authors focus on the key features of aggressive B- and T-cell lymphomas, aiming to contribute to the cross-talk between pathologists and clinicians.
  
  
  METHODS
  Each lymphoma entity is analyzed on the basis of the most representative contributions in the literature and the authors' experience gained in studying more than 20,000 lymphoid tumors over a 20-year period.
  
  
  RESULTS
  Guidelines for diagnosis and areas of interest for future clinico-pathologic studies are identified and discussed. Within this context, selected data obtained by the application of novel markers are presented.
  
  
  CONCLUSIONS
  The present know- ledge and organization of malignant lymphomas now make the development of tailored therapies a feasible goal.
authors: Service of Pathologic Anatomy and Hematopathology, Institute of Hematology and Oncology L. & A. Seràgnoli, Bologna University, Policlinico S. Orsola, Italy. pileri@almadns.unibo.it
authors: S A
authors: SA
authors: Pileri
authors: S
authors: S
authors: Ascani
authors: E
authors: E
authors: Sabattini
authors: G
authors: G
authors: Fraternali-Orcioni
authors: S
authors: S
authors: Poggi
authors: M
authors: M
authors: Piccioli
authors: P P
authors: PP
authors: Piccaluga
authors: B
authors: B
authors: Gamberi
authors: P L
authors: PL
authors: Zinzani
authors: L
authors: L
authors: Leoncini
authors: B
authors: B
authors: Falini
mesh_terms: D006801:Humans; D016130:Immunophenotyping; D008223:Lymphoma / Q000145:classification* / Q000276:immunology / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000145:classification / Q000276:immunology / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000145:classification / Q000276:immunology / Q000473:pathology; D017410:Practice Guidelines as Topic