title: Recent advances in the biology of addiction.
abstract: Recent research into the biologic basis of drug addiction continues to offer considerable promise for understanding how neurochemistry, pharmacology, and molecular biology relate to the reinforcing effects of abused drugs. One area of research is the development and pharmacologic and neurochemical characterization of cocaine and opiate polydrug abuse, a growing subset of the drug abuse population. Considerable advances have also been made in understanding how chronic and persistent drug use induces biochemical and molecular biologic adaptations in brain regions related to drug reinforcement.
authors: Neuroscience Division, 1026 Yerkes Regional Primate Research Center, 954 Gatewood Road NE, Atlanta, GA 30329, USA.
authors: S E
authors: SE
authors: Hemby
mesh_terms: D000818:Animals; D003042:Cocaine / Q000494:pharmacology*; D004195:Disease Models, Animal; D018765:Dopamine Uptake Inhibitors / Q000494:pharmacology*; D006801:Humans; D051381:Rats; D011954:Receptors, Dopamine / Q000502:physiology; D012054:Reinforcement, Psychology; D019966:Substance-Related Disorders / Q000503:physiopathology*
chemical_list: D018765:Dopamine Uptake Inhibitors; D011954:Receptors, Dopamine; D003042:Cocaine