title: Hemodynamic performance of small-size bileaflet valves: pressure drop and laser Doppler anemometry study comparison of three prostheses.
abstract: Laser Doppler anemometry (LDA) is a single-point technique which is unparalleled to detect accurately the local properties of the velocity field in a turbulent flow, such as that generated by a prosthetic heart valve (PHV). We propose a correlation between the structure of the flow field in three 19 mm bileaflet PHVs (Sorin Bicarbon, St. Jude Standard, St. Jude HP), investigated at peak systole (6 L/min cardiac output [CO]) with LDA, in kinematic and geometric similarity, and the global parameter of transvalvular pressure drop measured in both steady and pulsatile conditions. The pressure transducers of the same apparatus were used to characterize pressure drops at different flow rates whereas the steady-flow case was studied with a highly accurate tester built in our laboratory. The 2 St. Jude models rank according to their internal orifice diameter (ID) with the standard model (with a smaller ID) providing higher pressure drops for each flow rate. Sorin Bicarbon, due to its leaflet geometry, generates a more complex flow field with respect to the 2 St. Jude flat-leaflet models and shows improved hemodynamical behavior in pulsatile conditions with respect to the stationary case due to differences in pressure recovery. This study can provide insights into a PHV's local flow structure and global hemodynamical parameters.
authors: Istituto Superiore di Sanità, Laboratory of Biomedical Engineering, Rome, Italy. Grigioni@SUN.ISS.IT
authors: M
authors: M
authors: Grigioni
authors: C
authors: C
authors: Daniele
authors: G
authors: G
authors: D'Avenio
authors: V
authors: V
authors: Barbaro
mesh_terms: D001783:Blood Flow Velocity; D006350:Heart Valve Prosthesis; D006439:Hemodynamics; D006801:Humans; D066298:In Vitro Techniques; D017078:Laser-Doppler Flowmetry; D008955:Models, Cardiovascular; D008961:Models, Structural; D011312:Pressure; D011474:Prosthesis Design; D011673:Pulsatile Flow