title: Limits to potent antiretroviral therapy.
abstract: The availability of potent combination antiretroviral therapy (ART), also known as highly active antiretroviral therapy or HAART has changed the prognosis of HIV infection. However, the benefits have to be seen in the context of deficiencies of current therapy: failure to eradicate the virus, the slow and potentially incomplete recovery of the immune system, the high prevalence of resistance, and the potential for long-term toxicity. Treatment strategies need to take into account these limits to better target those HIV-infected patients who could benefit the most from antiretroviral therapy.
authors: Division of Infectious Diseases, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. amalio.telenti@chuv.hospvd.ch
authors: A
authors: A
authors: Telenti
authors: G
authors: G
authors: Paolo Rizzardi
mesh_terms: D019380:Anti-HIV Agents / Q000494:pharmacology / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D004352:Drug Resistance, Microbial; D015658:HIV Infections / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D015497:HIV-1 / Q000187:drug effects; D006801:Humans
chemical_list: D019380:Anti-HIV Agents