In vitro spatial compound scanning for improved visualization of atherosclerosis.
A new off-line multiangle ultrasound (US) compound scanner has been built with the purpose of investigating possible improvements in visualization of vascular structure. Images of two formalin-fixed human atherosclerotic plaques removed by carotid endarterectomy were recorded from seven insonification angles over a range of 42 degrees and the individual images were combined (averaged) into a single image (spatial compounding). Compared to conventional B-mode imaging, this multiangle compound imaging (MACI) method features images with reduced angle-dependence, reduced random variation (speckle) and improved delineation of the plaque outline. With the MACI approach, it is, thus, easier to assess e.g., a possible residual lumen of an atherosclerotic artery as well as the level of echogenicity for the different plaque constituents.
Jespersen
S K
SK
Center for Arteriosclerosis Detection with Ultrasound (CADUS), 1B-K Medical A/S, Gentofte, Denmark.
Wilhjelm
J E
JE
Sillesen
H
H
D001161:Arteriosclerosis / Q000000981:diagnostic imaging*; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging*; D005557:Formaldehyde; D006801:Humans; D007091:Image Processing, Computer-Assisted; D066298:In Vitro Techniques; D016707:Tissue Fixation; D014463:Ultrasonography / Q000295:instrumentation / Q000379:methods
D005557:Formaldehyde