title: Merging the old skeletal biology with the new. II. Molecular aspects of bone formation and bone growth.
abstract: Molecular aspects of bone formation and bone growth are discussed together with selected genetic disorders of the involved genes. Topics covered include: collagenopathies and osteogenesis imperfecta; core binding factor transcription factors and cleidocranial dysplasia; bone morphogenetic proteins and fibrodysplasia ossificans progressiva; transforming growth factor beta, suture closure, and craniosynostosis; Indian hedgehog, parathyroid hormone-related protein together with its receptor, and Jansen metaphyseal chondrodysplasia.
authors: Department of Oral & Maxillofacial Sciences, Dalhousie University, Halifax, Nova Scotia, Canada. remaclea@is.dal.ca
authors: M M
authors: MM
authors: Cohen
mesh_terms: D001846:Bone Development / Q000235:genetics / Q000502:physiology*; D001847:Bone Diseases / Q000235:genetics*; D020219:Chondrogenesis / Q000502:physiology; D003094:Collagen / Q000235:genetics; D003095:Collagen Diseases / Q000235:genetics*; D003240:Connective Tissue Diseases / Q000235:genetics*; D006801:Humans; D010012:Osteogenesis / Q000502:physiology
chemical_list: D003094:Collagen