The CYP2E1 knockout delivers another punch: first ASH, now NASH. Alcoholic steatohepatitis. Nonalcoholic steatohepatitis.
Maher
J
J
Liver Center and Department of Medicine, University of California San Francisco, USA.
D000818:Animals; D002384:Catalysis; D019392:Cytochrome P-450 CYP2E1 / Q000235:genetics / Q000502:physiology*; D042926:Cytochrome P-450 CYP4A; D003577:Cytochrome P-450 Enzyme System / Q000502:physiology; D005234:Fatty Liver / Q000209:etiology*; D006505:Hepatitis / Q000209:etiology*; D008054:Lipid Peroxides / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout / Q000235:genetics; D008862:Microsomes, Liver / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000502:physiology
D008054:Lipid Peroxides; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D019392:Cytochrome P-450 CYP2E1; D042926:Cytochrome P-450 CYP4A