Advances in male contraception.
The methods devised for male contraception are meager. The authors review the various nonhormonal methods applied for contraception including vas deferens interference and heat. The former comprises the no-scalpel vasectomy, percutaneous vasal injection, the "Shug" method, and the argon laser vasal photocoagulation. Heat methods used wet heat, and artificial cryptorchidism was created by testicular suspension. The testicle was suspended in the superficial inguinal pouch close to the scrotal neck using 2 methods: stitch and ball. Two recently developed methods for male contraception--polyester-induced azoospermia and prolactin injection--are described. The azoospermic effect of the polyester sling seems to be due to (1) creation of an electrostatic field across the intrascrotal structures, and (2) disordered thermoregulation. Prolactin administration as a contraceptive method is efficient and safe and has the potential to be developed as a male contraceptive. The methods, especially testicular suspension and polyester suspensors, are simple and easily applicable and were well accepted by the subjects.
Shafik
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A
Department of Surgery and Experimental Research, Faculty of Medicine, Cairo University, Egypt. shafisci@link.com.eg
D000818:Animals; D003272:Contraceptive Agents, Male / Q000494:pharmacology; D003275:Contraceptive Devices, Male; D003456:Cryptorchidism; D006358:Hot Temperature; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000209:etiology; D011388:Prolactin / Q000494:pharmacology; D014659:Vasectomy
D003272:Contraceptive Agents, Male; D011388:Prolactin