title: A high molecular mass constituent of cranberry juice inhibits helicobacter pylori adhesion to human gastric mucus.
abstract: Because previous studies have shown that a high molecular mass constituent of cranberry juice inhibited adhesion of Escherichia coli to epithelial cells and coaggregation of oral bacteria, we have examined its effect on the adhesion of Helicobacter pylori to immobilized human mucus and to erythrocytes. We employed three strains of H. pylori all of which bound to the mucus and agglutinated human erythrocytes via a sialic acid-specific adhesin. The results showed that a high molecular mass constituent derived from cranberry juice inhibits the sialic acid-specific adhesion of H. pylori to human gastric mucus and to human erythrocytes.
authors: Faculty of Food Engineering and Biotechnology, Institute of Technology, Technion, Haifa, Israel.
authors: O
authors: O
authors: Burger
authors: I
authors: I
authors: Ofek
authors: M
authors: M
authors: Tabak
authors: E I
authors: EI
authors: Weiss
authors: N
authors: N
authors: Sharon
authors: I
authors: I
authors: Neeman
mesh_terms: D001422:Bacterial Adhesion; D001628:Beverages; D004912:Erythrocytes / Q000382:microbiology*; D005638:Fruit / Q000737:chemistry*; D016481:Helicobacter Infections / Q000382:microbiology; D016480:Helicobacter pylori / Q000472:pathogenicity / Q000502:physiology*; D006801:Humans; D009093:Mucus / Q000382:microbiology*; D019158:N-Acetylneuraminic Acid; D013270:Stomach
chemical_list: D019158:N-Acetylneuraminic Acid