Retinal vein thrombosis associated with chronic hepatitis C: a case series and review of the literature.
The role of procoagulant autoantibodies in hepatitis C virus (HCV) infection is unclear. Three individuals with HCV infection and a unique genetic hypercoagulable state developed retinal vein thrombosis (RVT) in association with interferon-alpha (IFN-alpha) therapy. It is probable that a combination of active HCV infection in a genetically susceptible individual receiving IFN-alpha accounted for the observed RVT.
Nadir
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Loyola University Medical Center, Department of Gastroenterology, Maywood, IL 60153, USA.
Amin
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A
Chalisa
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van Thiel
D H
DH
D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D005260:Female; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007371:Interferon-gamma / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012170:Retinal Vein Occlusion / Q000209:etiology*
D000998:Antiviral Agents; D007371:Interferon-gamma