title: On the accuracy of EPI-based phase contrast velocimetry.
abstract: For over a decade, echo-planar imaging (EPI) has been used in both the medical and applied sciences to capture velocity fields of fluid flows. However, previous studies have not rigorously confirmed the accuracy of the measurements or sought to understand the limitations of the technique. In this study, a bipolar gradient was added to a flow-compensated EPI pulse sequence to obtain rapid phase contrast images of steady and unsteady flows through two step stenoses. For steady Re = 100 and 258 flows, accuracy was measured through systematic comparisons with CFD simulations, mass flow rate measurements, and spin echo phase contrast images. On average, the EPI image data exhibited velocity errors of 5 to 10 percent, while mass was conserved to within 5.6 percent at each axial position. Compared to spin-echo phase contrast images, the EPI images have 50 percent lower signal-to-noise ratio, larger local velocity errors, and similar mass conservation characteristics. An unsteady flow was then examined by starting a pump and allowing it to reach a steady Re = 100 flow. Accuracy in this case was measured by the consistency between mass flow rate measurements at different axial positions. Images taken at 0.3 s intervals captured the velocity field evolution and showed that 50 to 100 percent errors occur when the flow changes on a time scale faster than the image acquisition time.
authors: Lab for Quantitative Visualization in Energetics, Department of Mechanical & Industrial Engineering, University of Illinois at Urbana-Champaign, 1206 West Green Street, Urbana, IL 61801, USA.
authors: K W
authors: KW
authors: Moser
authors: J G
authors: JG
authors: Georgiadis
authors: R O
authors: RO
authors: Buckius
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology*; D003251:Constriction, Pathologic / Q000503:physiopathology; D017352:Echo-Planar Imaging / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging; D012212:Rheology