[General cerebral and systemic metabolic disturbances occurring in ischemic stroke with special emphasis on glucose and its metabolites].
Ischaemic stroke is a stressogenic factor triggering a complex defensive reaction called "alarm reaction" by Selye. Stress gives rise to liberation of catecholamines, dopamine beta-hydroxylase in the blood, cerebro-spinal fluid and urine. Patients with ischaemic stroke were found to have increased adrenaline, noradrenaline, and 3-metoxy-4-hydroxymandelic acid level in urine and increased cortisol level in blood serum. Patients, especially those with severe ischaemic stroke have increased concentrations of glucose metabolites in blood and cerebro-spinal fluid: pyruvate acid, lactic acid, acetylacetic acid and hydroxybutyric acid.
Pilarczyk
M
M
Katedry i Kliniki Neurologii Akademii Medycznej w Lublinie.
Krasińska-Czerlunczakiewicz
H
H
Tynecka-Turowska
M
M
Stelmasiak
Z
Z
D004837:Epinephrine / Q000097:blood; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D002546:Ischemic Attack, Transient / Q000150:complications* / Q000378:metabolism*; D008333:Mandelic Acids / Q000652:urine; D009638:Norepinephrine / Q000097:blood; D013312:Stress, Physiological / Q000150:complications* / Q000378:metabolism
D008333:Mandelic Acids; C045943:3-ethoxy-4-hydroxymandelic acid; D005947:Glucose; D006854:Hydrocortisone; D009638:Norepinephrine; D004837:Epinephrine