Gene expression profiling of cardiovascular disease models.
Recent development of gene expression profiling technologies has enabled the large-scale analysis of gene expression changes during disease progression. Frequently, cardiovascular diseases involve complex interactions of multiple cell types over prolonged periods of time. A better understanding of the pathology of cardiovascular diseases and the potential identification of underlying genetic defects are currently being explored by using profiling methodologies in a number of animal and tissue-culture models.
Shiffman
D
D
CV Therapeutics Inc., 3172 Porter Drive, Palo Alto, CA 94304, USA. ds@CVT.com
Porter
J G
JG
D000818:Animals; D002318:Cardiovascular Diseases / Q000235:genetics*; D004195:Disease Models, Animal; D020869:Gene Expression Profiling; D006801:Humans; D012313:RNA / Q000235:genetics / Q000378:metabolism
D012313:RNA