title: Duodenal and ampullary obstruction by a Peutz-Jeghers polyp.
abstract: We report a case of Peutz-Jeghers syndrome presenting with obstruction of the second part of the duodenum and the ampulla of Vater by a large intra-luminal polyp leading to duodenal obstruction and obstructive jaundice. CT scan of the abdomen showed a large polypoidal lesion, a caecal polyp and jejuno-jejunal intussusception. At surgery, two intussusceptions were reduced and leading polyps were excised via two enterotomies; the caecal polyp was excised via caecotomy. The duodenal polyp was excised by limited duodenectomy after frozen section has shown no evidence of malignancy. Histopathological study of all the excised polyps including that of the duodenum showed hamartomatous polyps with no malignant changes. Apart from acute bleeding, this case highlights many of the surgical gastrointestinal complications of Peutz-Jeghers syndrome. It also highlights the unusual combined duodenal and common bile duct obstruction by a large Peutz-Jeghers polyp. The controversial association of this syndrome with cancer and management options is also discussed.
authors: Department of Surgery, Dammam Central Hospital, Eastern Province, Saudi Arabia. meshikhes@doctor.com
authors: A W
authors: AW
authors: Meshikhes
authors: O
authors: O
authors: Al-Saif
authors: M
authors: M
authors: Al-Otaibi
mesh_terms: D000328:Adult; D014670:Ampulla of Vater; D002779:Cholestasis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D004386:Duodenum; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D007443:Intussusception / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery; D016577:Pancreaticoduodenectomy; D010580:Peutz-Jeghers Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D014057:Tomography, X-Ray Computed