title: Optical coherence tomographic features of idiopathic submacular choroidal neovascularization.
abstract: OBJECTIVE
  To clarify the morphologic features of idiopathic submacular choroidal neovascularization using optical coherence tomography.
  
  
  METHODS
  Using optical coherence tomography, we prospectively examined 17 consecutive eyes (17 patients; eight men, nine women; mean age +/- SD, 36.0 +/- 9.3 years) with idiopathic submacular choroidal neovascularization. During the follow-up period (mean +/- SD, 7.5 +/- 3.8 months), we repeated optical coherence tomography in 15 eyes; optical coherence tomography was performed only at the initial examination in two eyes that underwent submacular surgery.
  
  
  RESULTS
  Choroidal neovascularization was observed in the subsensory retinal space anterior to the retinal pigment epithelium as a highly or moderately reflective mass, which protruded from the retinal pigment epithelium in 13 of 17 eyes (protruding type). In four eyes, choroidal neovascularization was a highly reflective fusiform mass at the level of the retinal pigment epithelium and choriocapillaris (fusiform type). During the follow-up period, choroidal neovascularization regressed and the protruding mass became a highly reflective fusiform mass in 10 of 11 eyes with the protruding type that underwent repeated examination. In three of the 10 eyes, during 5 to 10 months from initial examination, the choroidal neovascularization was exacerbated and it again protruded into the subsensory retinal space anterior to the retinal pigment epithelium. Four eyes with the fusiform type remained the same throughout the follow-up period. The overlying retina was thickened and had low reflectivity in all 17 eyes at the initial examination. Optical coherence tomography identified subretinal fluid in only 11 of the 13 eyes with protruding type choroidal neovascularization.
  
  
  CONCLUSIONS
  Optical coherence tomography confirmed subsensory retinal location of idiopathic submacular choroidal neovascularization anterior to the retinal pigment epithelium. Protruding choroidal neovascularization transforms to fusiform tissue at the level of the retinal pigment epithelium during the process of regression. Sensory retinal edema was always associated with choroidal neovascularization.
authors: Department of Ophthalmology, Gunma University School of Medicine, Maebashi, Gunma, Japan. iidatomo@showa.gunma-u.ac.jp
authors: T
authors: T
authors: Iida
authors: N
authors: N
authors: Hagimura
authors: T
authors: T
authors: Sato
authors: S
authors: S
authors: Kishi
mesh_terms: D000328:Adult; D020256:Choroidal Neovascularization / Q000175:diagnosis* / Q000503:physiopathology; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007368:Interferometry; D008027:Light; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014054:Tomography / Q000379:methods