title: Pedal bypass for limb salvage: impact of diabetes on long-term outcome.
abstract: Use of pedal bypass can salvage limbs of patients with critical ischemia. The aim of this study was to evaluate the results of surgical revascularization of pedal arteries in diabetic patients and to assess the impact of diabetes on long-term outcome. We performed a retrospective analysis of all consecutive pedal bypasses done between January 1, 1987 and December 31, 1997. Demographic data, surgical indications, operative variables, and postoperative results including graft patency and limb salvage were compared between diabetic and nondiabetic patients. The results of this comparison showed that pedal bypass can safely and effectively relieve critical ischemia in diabetic patients. Diabetics have less early graft thrombosis and superior long-term graft patency. Despite higher incidence of renal insufficiency or failure and more tissue loss, diabetics can achieve similar excellent limb salvage rates. This outcome justifies aggressive revascularization of pedal arteries in diabetic as well as nondiabetic patients with critical limb ischemia.
authors: Division of Vascular Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors: J M
authors: JM
authors: Panneton
authors: P
authors: P
authors: Gloviczki
authors: T C
authors: TC
authors: Bower
authors: J M
authors: JM
authors: Rhodes
authors: L G
authors: LG
authors: Canton
authors: B J
authors: BJ
authors: Toomey
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019917:Blood Vessel Prosthesis Implantation; D003925:Diabetic Angiopathies / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005528:Foot / Q000098:blood supply*; D006083:Graft Occlusion, Vascular / Q000401:mortality; D006801:Humans; D007511:Ischemia / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D015996:Survival Rate; D016896:Treatment Outcome