[Recurrent Clostridium difficile enterocolitis].
Pseudomembranous enterocolitis generally occurs after antibiotic treatment. The standard treatment is oral metronidazol or vancomycin. Nevertheless, relapses of Clostridium difficile enterocolitis are observed in 10-25% of cases. Factors associated with recurrences include endogenous reinfection by spore formation, selective IgG1 or IgA deficiency or infection with mutated strains of Clostridium difficile. Recurrent Clostridium difficile enterocolitis may be treated with repeat oral vancomycin combined with Sacchoromyces boulardii, with intravenous immunoglobulin for severe colitis.
Bergamin
B
B
Medizinische Klinik, Kantonsspital Winterthur.
Hess
T
T
Jost
R
R
Ballmer
P E
PE
Imoberdorf
R
R
D000368:Aged; D000369:Aged, 80 and over; D016360:Clostridioides difficile; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004761:Enterocolitis, Pseudomembranous / Q000188:drug therapy / Q000503:physiopathology* / Q000628:therapy*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008795:Metronidazole / Q000627:therapeutic use; D012008:Recurrence; D012440:Saccharomyces; D014640:Vancomycin / Q000627:therapeutic use
D016756:Immunoglobulins, Intravenous; D008795:Metronidazole; D014640:Vancomycin