title: Copper accumulation and phosphatase activities of Aspergillus and Rhizopus.
abstract: Copper accumulation and phosphatase activities of three Aspergillus species resistant to copper were compared to three copper-sensitive Rhizopus species. High level of acid phosphatases and decreased Cu2+-uptake were found with resistant in contrast to sensitive strains. The presence of copper(II) ions in the medium increased the production of acid phosphatases in the resistant A. niger and decreased their activity in the sensitive R. delemar. Copper ions inhibited the activity of A. niger cellular acid phosphatase with a Ki of 8.9x10(-4) M and slightly activated the R. delemar enzyme.
authors: Laboratory of Microbial Ecology, Institute of Microbiology, Bulgarian Academy of Sciences, Sofia.
authors: K
authors: K
authors: Tsekova
authors: D
authors: D
authors: Galabova
authors: K
authors: K
authors: Todorova
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D001230:Aspergillus / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D001234:Aspergillus niger / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D001692:Biological Transport; D003300:Copper / Q000378:metabolism* / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D007700:Kinetics; D012233:Rhizopus / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*
chemical_list: D003300:Copper; D000135:Acid Phosphatase