Novel carbon-carbon bond formation reaction of methoxyallene oxide promoted by TiI(4)
Methoxyallene oxide was readily prepared in situ by epoxidation of methoxyallene with 3-chloroperbenzoic acid, and the subsequent reaction with aldehydes or acetals was promoted by titanium tetraiodide and additives to give 2,3-dialkoxy- or 3-hydroxy-2-methoxy ketones in good yields.
Hayakawa
R
Department of Chemistry for Materials, Mie University, Tsu, Mie 514-8507, Japan.
Shimizu
M