[Hyperaggregation syndrome in patients with osteolytic psoriatic arthritis].
OBJECTIVE
To study blood rheology in patients with psoriatic arthritis (PA) having local or advanced osteolysis.


METHODS
The trial included 16 patients with significant PA and clinical and x-ray symptoms of joint surface osteolysis. Kinetics of red cell aggregation and disaggregation was studied in specially designed erythroagregometer.


RESULTS
The assessment of red cell aggregation indicated the presence of hyperaggregation syndrome in the majority of PA patients with associated osteolysis.


CONCLUSIONS
Hyperaggregation may contribute to bone destruction. Its onset can be reviewed as a risk factor for serious destructive changes in the joints.
Korotaeva
T V
TV
Firsov
N N
NN
Vyshlova
M A
MA
D000293:Adolescent; D000328:Adult; D015535:Arthritis, Psoriatic / Q000097:blood* / Q000150:complications; D001778:Blood Coagulation Disorders / Q000097:blood* / Q000209:etiology; D018450:Disease Progression; D004903:Erythrocyte Aggregation; D005260:Female; D006403:Hematologic Tests; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013577:Syndrome