Acute electrophysiologic effect of estradiol 17beta in menopausal women.
Sixteen postmenopausal women underwent electrophysiologic study before and 20 minutes after the administration of sublingual estradiol 17beta or placebo. Estradiol 17beta significantly affected electrophysiologic parameters, thereby suggesting its role in the development of palpitations in women.
Rosano
G M
GM
Department of Cardiology, Istituto H San Raffale, Milan, Italy. Rosanog@sanrafaele.it
Leonardo
F
F
Dicandia
C
C
Sheiban
I
I
Pagnotta
P
P
Pappone
C
C
Chierchia
S L
SL
D000286:Administration, Sublingual; D000704:Analysis of Variance; D001283:Atrioventricular Node / Q000503:physiopathology; D002036:Bundle of His / Q000503:physiopathology; D005117:Cardiac Complexes, Premature / Q000503:physiopathology; D002304:Cardiac Pacing, Artificial; D004311:Double-Blind Method; D004562:Electrocardiography / Q000187:drug effects*; D004594:Electrophysiology; D004958:Estradiol / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008593:Menopause / Q000097:blood; D008875:Middle Aged; D010919:Placebos; D012032:Refractory Period, Electrophysiological / Q000187:drug effects; D012815:Signal Processing, Computer-Assisted; D013617:Tachycardia, Supraventricular / Q000503:physiopathology
D010919:Placebos; D004958:Estradiol