[Use of kinetic hemagglutination inhibition test in study of antigenic relationships of hantavirus strains circulating in foci of hemorrhagic fever with renal syndrome in Southern Far East of Russia].
The kinetics of reaction between hemagglutinating antigens and immune sera to 10 hantavirus strains (7 isolated in the Primorye territory and 3 in other regions) was studied in the cross kinetic hemagglutination inhibition (KHAI) test. An A parameter is suggested for evaluation of the similarity and differences between the studied strains. This parameter helped detect antigenic differences between Hantaan and Seoul viruses and the inter-type differences between Hantaan-like strains. KHAI is more specific than HAI studies of antigenic relationships between strains of different hantavirus serotypes.
Kushnareva
T V
TV
Slonova
R A
RA
Kompanets
G G
GG
Pysina
T V
TV
D000956:Antigens, Viral / Q000276:immunology*; D005202:Asia, Eastern / Q000453:epidemiology; D006476:Orthohantavirus / Q000276:immunology*; D006385:Hemagglutination Inhibition Tests; D006480:Hemorrhagic Fever with Renal Syndrome / Q000453:epidemiology / Q000276:immunology* / Q000821:virology*; D006801:Humans; D012426:Russia / Q000453:epidemiology
D000956:Antigens, Viral