title: Developmental genetics: vertebrates and insects see eye to eye.
abstract: The results of a number of recent studies indicate that eye development in insects and vertebrates may have more features in common than hitherto suspected. The results support the possibility that insect and vertebrate eyes evolved from a complex ancestral organ.
authors: The Wellcome Trust Centre for Cell Biology, Institute of Cell and Molecular Biology, University of Edinburgh, UK. andrew.jarman@ed.ac.uk
authors: A P
authors: AP
authors: Jarman
mesh_terms: D000818:Animals; D051792:Basic Helix-Loop-Helix Proteins; D005075:Biological Evolution; D019521:Body Patterning; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D004330:Drosophila / Q000196:embryology* / Q000235:genetics; D029721:Drosophila Proteins; D005123:Eye / Q000196:embryology*; D005136:Eye Proteins; D018507:Gene Expression Regulation, Developmental; D053823:Hedgehog Proteins; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism; D019476:Insect Proteins / Q000235:genetics / Q000378:metabolism; D051379:Mice; D009419:Nerve Tissue Proteins; D000071841:PAX6 Transcription Factor; D051761:Paired Box Transcription Factors; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D012097:Repressor Proteins; D012160:Retina / Q000196:embryology; D015398:Signal Transduction; D015534:Trans-Activators; D014714:Vertebrates / Q000196:embryology* / Q000235:genetics
chemical_list: D051792:Basic Helix-Loop-Helix Proteins; D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D005136:Eye Proteins; D053823:Hedgehog Proteins; D018398:Homeodomain Proteins; D019476:Insect Proteins; D009419:Nerve Tissue Proteins; D000071841:PAX6 Transcription Factor; D051761:Paired Box Transcription Factors; D011506:Proteins; D012097:Repressor Proteins; D015534:Trans-Activators; C500943:Atoh1 protein, mouse; C000605732:Pax6 protein, mouse; C082142:ato protein, Drosophila; C077245:hh protein, Drosophila