Invasive medullary thymoma associated with Myasthenia gravis: an unusual case.
Thymomas are tumors characterized by a remarkable morphological heterogeneity and variable clinical behavior. This tumor has unique clinical associations, most notably with hematological abnormalities and myasthenia gravis. According with the Müller-Hermelink criteria, there are significant differences between the histological types of thymomas and the association with myasthenia gravis. Among the different histological types, medullary thymoma is the least frequent variant associated with this autoimmune disease. In this report we describe a case of medullary thymoma presenting in a 71-year- old woman with a myasthenic syndrome.
Reis Filho
J S
JS
Hospital de Clínicas, Universidade Federal do Paraná, Sao Paulo, Brazil. jsreis@hotmail.com
Milanezi
M F
MF
Moreira
C G
CG
Werneck
L C
LC
Boscardin
P
P
Ioshii
S O
SO
Schmitt
F C
FC
D000368:Aged; D005260:Female; D006801:Humans; D009157:Myasthenia Gravis / Q000150:complications* / Q000473:pathology; D013945:Thymoma / Q000150:complications* / Q000473:pathology; D013953:Thymus Neoplasms / Q000150:complications* / Q000473:pathology