Fetal diagnosis of lethal dysfunction of the right heart in three siblings.
A woman, having already delivered one child, underwent fetal echocardiography during three subsequent pregnancies. All three showed enlargement and poor function of the right-sided chambers. The first was still-born, the second died as a neonate, while the third pregnancy was terminated. Pathological examination revealed the same findings in each fetus, possibly representing a variation of Uhl's anomaly, or alternatively a hitherto unrecognised cardiomyopathic process.
Hornung
T S
TS
Department of Paediatric Cardiology, Freeman Hospital, Newcastle-upon-Tyne, UK. tim.hornung@virgin.net
Heads
A
A
Wright
C
C
Hunter
S
S
D000328:Adult; D006332:Cardiomegaly / Q000000981:diagnostic imaging / Q000235:genetics; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000235:genetics; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D011247:Pregnancy; D011665:Pulmonary Valve Insufficiency / Q000000981:diagnostic imaging* / Q000235:genetics; D014262:Tricuspid Valve Insufficiency / Q000000981:diagnostic imaging* / Q000235:genetics; D016216:Ultrasonography, Prenatal