title: Fatty acid amide hydrolase substrate specificity.
abstract: Fatty acid amide hydrolase (FAAH), also referred to as oleamide hydrolase and anandamide amidohydrolase, is a serine hydrolase responsible for the degradation of endogenous oleamide and anandamide, fatty acid amides that function as chemical messengers. FAAH hydrolyzes a range of fatty acid amides, and the present study examines the relative rates of hydrolysis of a variety of natural and unnatural fatty acid primary amide substrates using pure recombinant rat FAAH.
authors: Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA. boger@scripps.edu
authors: D L
authors: DL
authors: Boger
authors: R A
authors: RA
authors: Fecik
authors: J E
authors: JE
authors: Patterson
authors: H
authors: H
authors: Miyauchi
authors: M P
authors: MP
authors: Patricelli
authors: B F
authors: BF
authors: Cravatt
mesh_terms: D000581:Amidohydrolases / Q000378:metabolism*; D000818:Animals; D006868:Hydrolysis; D051381:Rats; D011994:Recombinant Proteins / Q000378:metabolism; D013379:Substrate Specificity; D000099252:Fatty Acid Amide Hydrolases
chemical_list: D000581:Amidohydrolases; D011994:Recombinant Proteins; D000099252:Fatty Acid Amide Hydrolases