Clinical report: contrast enhancement of tumor perfusion as a guidance for biopsy.
We describe three cases where biopsies from various tumors were guided by contrast enhancement of tumor perfusion. After i.v. administration of Levovist (Schering AG, Berlin, Germany), the tumors showed both hyper- and hypovascular areas. Biopsies from the latter showed marked necrosis or fibrosis. This may cause biopsies not being conclusive. To ensure fully diagnostic biopsies from irregular tumors we propose the biopsy to be performed from the most vascular part demonstrated by contrast enhancement.
Bang
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Department of Radiology, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK 2100, Denmark. rh07048@rh.dk
Bachmann Nielsen
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M
Vejborg
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I
Mellon Mogensen
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A
D000008:Abdominal Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging*; D001706:Biopsy; D001943:Breast Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging*; D002292:Carcinoma, Renal Cell / Q000098:blood supply / Q000000981:diagnostic imaging*; D003287:Contrast Media / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging*; D008875:Middle Aged; D018319:Neurofibrosarcoma / Q000098:blood supply / Q000000981:diagnostic imaging*; D011134:Polysaccharides / Q000008:administration & dosage; D018084:Ultrasonography, Interventional
D003287:Contrast Media; D011134:Polysaccharides; C059891:SHU 508