5-Methyl-2'-deoxy-4'-thio-alpha-uridine (R)-S-oxide.
The pyrimidine ring of the title compound, C(10)H(14)N(2)O(5)S, is planar to within 0.024 (1) A and makes an angle of 75.46 (10) degrees with the mean plane of the thiosugar ring. In terms of standard nucleoside nomenclature, this ring has the C3'-endo conformation. The O5'-C5'-C4'-C3' torsion angle is 166.5 (3) degrees and the glycosidic torsion angle S4'-C1'-N1-C2 is -52.1 (2) degrees (syn).
Sun
M
M
School of Chemistry, University of Birmingham, Birmingham B15 2TT, England.
Macculloch
A C
AC
Hamor
T A
TA
Walker
R T
RT
D000998:Antiviral Agents / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003499:Cyclic S-Oxides / Q000737:chemistry*; D006860:Hydrogen Bonding; D015394:Molecular Structure; D013891:Thiouridine / Q000031:analogs & derivatives* / Q000737:chemistry
C420707:5-methyl-2'-deoxy-4'-thiouridine; D000998:Antiviral Agents; D003499:Cyclic S-Oxides; D013891:Thiouridine