[Progressive multifocal leukoencephalopathy and pulmonary sarcoidosis].
An association of progressive multifocal leukoencephalopathy (PML) and sarcoidosis in a 47 year-old-woman is reported. This is the third case in which PML has been diagnosed by PCR. Clinical, biological and radiological features were in agreement with previous findings in immunologically suppressed patients. JC virus should be systematically detected by PCR in blood and cerebrospinal fluid (CSF) in patients with sarcoidosis presenting neurological and radiological PML manifestations.
Olindo
S
S
Clinique Neurologique, Hôpital G. et R. Laennec, CHU Nantes 44035.
Guillon
B
B
Faighel
M
M
Fève
J R
JR
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D001921:Brain / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D017403:In Situ Hybridization; D007968:Leukoencephalopathy, Progressive Multifocal / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009836:Oligodendroglia / Q000473:pathology; D016133:Polymerase Chain Reaction; D017565:Sarcoidosis, Pulmonary / Q000150:complications* / Q000175:diagnosis; D013238:Stereotaxic Techniques
D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone