title: Protein Information Resource: a community resource for expert annotation of protein data.
abstract: The Protein Information Resource, in collaboration with the Munich Information Center for Protein Sequences (MIPS) and the Japan International Protein Information Database (JIPID), produces the most comprehensive and expertly annotated protein sequence database in the public domain, the PIR-International Protein Sequence Database. To provide timely and high quality annotation and promote database interoperability, the PIR-International employs rule-based and classification-driven procedures based on controlled vocabulary and standard nomenclature and includes status tags to distinguish experimentally determined from predicted protein features. The database contains about 200,000 non-redundant protein sequences, which are classified into families and superfamilies and their domains and motifs identified. Entries are extensively cross-referenced to other sequence, classification, genome, structure and activity databases. The PIR web site features search engines that use sequence similarity and database annotation to facilitate the analysis and functional identification of proteins. The PIR-Inter-national databases and search tools are accessible on the PIR web site at http://pir.georgetown.edu/ and at the MIPS web site at http://www.mips.biochem.mpg.de. The PIR-International Protein Sequence Database and other files are also available by FTP.
authors: National Biomedical Research Foundation, 3900 Reservoir Road, LR-3, NW, Washington, DC 20007, USA. pirmail@nbrf.georgetown.edu
authors: W C
authors: WC
authors: Barker
authors: J S
authors: JS
authors: Garavelli
authors: Z
authors: Z
authors: Hou
authors: H
authors: H
authors: Huang
authors: R S
authors: RS
authors: Ledley
authors: P B
authors: PB
authors: McGarvey
authors: H W
authors: HW
authors: Mewes
authors: B C
authors: BC
authors: Orcutt
authors: F
authors: F
authors: Pfeiffer
authors: A
authors: A
authors: Tsugita
authors: C R
authors: CR
authors: Vinayaka
authors: C
authors: C
authors: Xiao
authors: L S
authors: LS
authors: Yeh
authors: C
authors: C
authors: Wu
mesh_terms: D019295:Computational Biology; D016208:Databases, Factual; D007255:Information Services; D020407:Internet; D011506:Proteins / Q000145:classification / Q000235:genetics; D009626:Terminology as Topic
chemical_list: D011506:Proteins