title: Roles of mast cells and basophils in innate and acquired immunity.
abstract: There have been several recent advances in knowledge about mast cells and basophils in immune responses, of which some are particularly important: a role has been found for heparin in the storage of certain proteases and other mediators in mast cell cytoplasmic granules; an important role for mast cells in the development of several chronic aspects of an asthma model in mice has been discovered; and a new approach has been developed, based on the generation of mast cells from embryonic stem cells in vitro, to investigate mast cell function in vitro or in vivo.
authors: Department of Pathology, L-235, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305-5324, USA. jochen_wedemeyer@yahoo.com
authors: J
authors: J
authors: Wedemeyer
authors: M
authors: M
authors: Tsai
authors: S J
authors: SJ
authors: Galli
mesh_terms: D000818:Animals; D001491:Basophils / Q000276:immunology*; D006801:Humans; D007110:Immunity, Active / Q000276:immunology; D007113:Immunity, Innate / Q000276:immunology; D007073:Immunoglobulin E / Q000276:immunology; D008407:Mast Cells / Q000276:immunology*; D010271:Parasites / Q000276:immunology; D010272:Parasitic Diseases / Q000276:immunology
chemical_list: D007073:Immunoglobulin E