title: Diffuse leiomyomatosis of the esophagus.
abstract: BACKGROUND
  Leiomyomas are rare esophagus neoplasms. They are usually solitary, and the diffuse lesion is extremely rare.
  
  
  METHODS
  A 19-year-old male presented with a 3-year history of occasional dysphagia and postprandial regurgitation. The chest radiographs showed a huge mass in the posterior mediastinum. Barium esophagograms showed narrowing of the middle third esophagus with proximal dilatation. The fibroesophagoscopy demonstrated multiple submucosal nodules below a level 22 cm from the incisor and covered with intact mucosa. CT scans of the chest showed a long segment of circumferential soft tissue in the posterior mediastinum which encircled and involved the upper two thirds of the esophagus. An intrathoracic esophagectomy with cervical esophagogastrostomy via the substernal route was performed. Grossly, multiple confluent myomatous nodules circumferentially involved the upper and middle third of the esophagus. Histologic findings showed diffuse leiomyomatosis of the esophagus.
  
  
  CONCLUSIONS
  Esophageal leiomyomatosis should be considered in a young patient with long-standing dysphagia in whom smooth, tapered esophageal narrowing on barium study and circumferential esophageal wall thickening on CT scan are seen. An esophagectomy combined with a reconstruction procedure is indicated.
authors: Division of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
authors: Y L
authors: YL
authors: Cheng
authors: J Y
authors: JY
authors: Hsu
authors: H H
authors: HH
authors: Hsu
authors: C P
authors: CP
authors: Yu
authors: S C
authors: SC
authors: Lee
mesh_terms: D000328:Adult; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D016629:Esophagectomy; D004946:Esophagostomy; D005774:Gastrostomy; D006801:Humans; D018231:Leiomyomatosis / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D014057:Tomography, X-Ray Computed