Transplantation of both kidneys from 408 donors; comparison of results.
The outcome of 816 paired kidney transplantations from 408 cadaveric donors was evaluated. The transplantations were divided according to order of transplant surgery into group 1 [mean cold ischemia time (CIT) 22 h] and group 2 (mean CIT 28 h). In group 1 the frequency of delayed onset of graft function (DGF) was 22% versus 35% in group 2 (P < 0.005). The 1-year patient survival and graft survival (GS) in group 1 was 98% and 93% versus 94% (P < 0.005) and 90% in group 2. Hemodialysis patients in group 2 had significantly greater DGF (43%) and poorer GS (88%) than peritoneal dialysis patients and the success of transplantation was particularly poor in recipients over 50 years of age.
Kyllönen
L
L
Department of Surgery, Helsinki University Central Hospital, Finland.
Salmela
K
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D002102:Cadaver; D005260:Female; D006085:Graft Survival; D006801:Humans; D007668:Kidney; D016030:Kidney Transplantation / Q000379:methods / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009926:Organ Preservation; D010530:Peritoneal Dialysis; D006435:Renal Dialysis; D012086:Reoperation; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors; D014019:Tissue Donors; D016896:Treatment Outcome