The efficacy of 1 alpha hydroxy vitamin D3 treatment of the metabolic bone disorder in patients who underwent gastrectomy for gastric cancer.
OBJECTIVE
The aim of this study was to elucidate the efficacy of 1 alpha hydroxy vitamin D3 for treatment of metabolic bone disorder after gastrectomy.


METHODS
MD-MS method was performed in 16 patients who underwent gastrectomy to evaluate the metabolic bone disorder and compared before and after 1 alpha hydroxy vitamin D3 treatment. The symp-toms related to the metabolic bone disorder were also analyzed through patient interview.


RESULTS
The severity of the metabolic bone disorder analyzed by the MD-MS method improved after 1 alpha hydroxy vitamin D3 treatment in 56.3% of patients. The deviation degree of the cortical bone density was also significantly improved. The symptoms related to metabolic bone disorder disappeared in 80% of patients after treatment.


CONCLUSIONS
The administration of 1 alpha hydroxy vitamin D3 may be useful for the metabolic bone disorder in the treatment of patients after gastrectomy.
Rino
Y
Y
First Department of Surgery, Yokohama City University, School of Medicine, Japan.
Imada
T
T
Yamamoto
Y
Y
Takahashi
M
M
Amano
T
T
Takanashi
Y
Y
D000368:Aged; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005743:Gastrectomy; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use*; D008297:Male; D011183:Postoperative Complications; D013274:Stomach Neoplasms / Q000601:surgery*
D006887:Hydroxycholecalciferols