Facile lewis acid catalyzed synthesis of C(4) symmetric resorcinarenes
The Lewis acid catalyzed condensation of 3-methoxyphenol with octanal produced the C(4) symmetric calix[4]resorcinarene 2, in high yield. Of the numerous stereo- and regioisomers possible, the rccc isomer with C(4) symmetry was the only product isolated (as a racemate). The structure has been established by single-crystal X-ray structure analysis.
McIldowie
MJ
School of Applied Chemistry, Curtin University of Technology, GPO Box U 1987, Perth, WA 6845, Australia, and Department of Chemistry, University of Western Australia, Nedlands, WA 6907, Australia.
Mocerino
M
Skelton
BW
White
AH