title: Acupuncture increases cell proliferation in dentate gyrus after transient global ischemia in gerbils.
abstract: The effects of acupuncture on cell proliferation in the dentate gyrus of gerbils after transient global ischemia were investigated in this study. Acupuncture was performed on Zusanli (ST36), which is a well known acupoint in animals and humans. In Oriental medicine, Zusanli has been commonly used for the enhancement of functional recovery in stroke patients. Through 5-bromo-2'-deoxyuridine (BrdU) immunohistochemistry, an increase in cell birth in the dentate gyrus of gerbils after ischemic injury was detected. Interestingly, acupunctural treatment in ischemic gerbils resulted in a significant increase in the number of BrdU-positive cells in the dentate gyrus. The present findings indicate that acupuncture may affect cell proliferation in the dentate gyrus of gerbils after ischemic injury.
authors: Department of Meridianology, College of Oriental Medicine, Semyung University, San 21-1, Shinwol-dong, Jechon, 390-711, Chungbuk, South Korea.
authors: E H
authors: EH
authors: Kim
authors: Y J
authors: YJ
authors: Kim
authors: H J
authors: HJ
authors: Lee
authors: Y
authors: Y
authors: Huh
authors: J H
authors: JH
authors: Chung
authors: J C
authors: JC
authors: Seo
authors: J E
authors: JE
authors: Kang
authors: H J
authors: HJ
authors: Lee
authors: S V
authors: SV
authors: Yim
authors: C J
authors: CJ
authors: Kim
mesh_terms: D015669:Acupuncture Points; D000818:Animals; D002545:Brain Ischemia / Q000378:metabolism / Q000473:pathology*; D001973:Bromodeoxyuridine / Q000378:metabolism; D002455:Cell Division / Q000502:physiology; D018891:Dentate Gyrus / Q000166:cytology* / Q000378:metabolism; D005849:Gerbillinae; D008297:Male
chemical_list: D001973:Bromodeoxyuridine