title: Immediate urodynamic and anatomic response to colposuspension in female Beagles.
abstract: OBJECTIVE
  To characterize urodynamic function and anatomy before and after colposuspension in anesthetized female Beagles.
  
  
  METHODS
  12 adult female Beagles. PROCEDURE; During general anesthesia (thiopental sodium induction and halothane maintenance), urethral pressure profiles, leak point pressure measurements with a 50-ml bladder volume, positive contrast cystograms, and retrograde vaginourethrocystograms were performed. A caudal midline laparotomy was used to perform colposuspension. Urodynamic and radiographic studies were repeated after surgery.
  
  
  RESULTS
  Leak point pressures were increased (120 to 168.9 cm H2O), and maximum urethral closure pressures decreased (43.7 to 19.3 cm H2O ) after colposuspension. The urethra and bladder were moved cranially; the external urethral orifice was positioned closer to the pelvic cavity, and the neck of the bladder was positioned more cranially into the abdomen. Length of the urethra, as measured by use of vaginourethrocystograms, was increased by 3%. As measured by use of urethral pressure profiles, total profile length was increased by 19.9%, and functional profile length was increased by 19.2%.
  
  
  CONCLUSIONS
  Increased leak-point pressure correlated with the expected clinical improvement attributable to colposuspension. Increased exposure of the urethra to abdominal and pelvic cavity pressures may be the mechanism by which incontinent dogs become continent after colposuspension. Results of the leak-point pressure test may correlate with clinical behavior before and after colposuspension for treatment of incontinence.
authors: Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602-7390, USA.
authors: C A
authors: CA
authors: Rawlings
authors: M B
authors: MB
authors: Mahaffey
authors: A
authors: A
authors: Chernosky
authors: L
authors: L
authors: Huzella
mesh_terms: D000768:Anesthesia, General / Q000662:veterinary; D018685:Anesthetics, Inhalation; D000818:Animals; D003127:Colposcopy / Q000662:veterinary*; D004283:Dog Diseases / Q000503:physiopathology / Q000601:surgery*; D004285:Dogs; D005260:Female; D006221:Halothane; D011859:Radiography; D013874:Thiopental; D014521:Urethra / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D001743:Urinary Bladder / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D014549:Urinary Incontinence / Q000503:physiopathology / Q000601:surgery / Q000662:veterinary*; D014563:Urodynamics; D014621:Vagina / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery
chemical_list: D018685:Anesthetics, Inhalation; D013874:Thiopental; D006221:Halothane