Lung cancer after head and neck cancer: role of chest radiography.
OBJECTIVE
To examine whether screening chest radiographs lead to significantly longer life span in patients found to have pulmonary lesions than in those in whom lung cancer was detected after symptoms developed.


METHODS
A retrospective study.


METHODS
Charts of 1,086 patients with squamous cell cancer of the head and neck treated for cure from January 1, 1974, to December 31, 1998, were analyzed.


RESULTS
Pulmonary cancer developed in 62 patients. In 41 patients pulmonary malignancy was found because of patient symptoms. In 21 patients lung cancer was detected by routine annual chest radiography. Seventy-five percent of lung cancers were detected within 3 years of initial treatment of the head and neck cancer.


CONCLUSIONS
Chest radiography is a poor screening tool, because it failed to find pulmonary lesions in more than 65% (41/62) of patients who were later found to have pulmonary cancer. Survival rate did not differ between patients in whom pulmonary cancer was found by screening chest radiography and those in whom symptoms prompted evaluation (P = .48). Using current treatment protocols, routine yearly chest radiography did not improve survival in patients with head and neck cancer. However, there maybe new therapeutic regimens under investigation that would benefit these patients if their lung cancers were found in early stages of disease. Future directives must include the establishment of an effective follow-up protocol for the early detection of lung malignancies in these patients.
Shah
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Department of Otolaryngology-Head and Neck Surgery, University of Illinois at Chicago, USA.
Applebaum
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality*; D006258:Head and Neck Neoplasms / Q000401:mortality*; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000401:mortality*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000401:mortality*; D011379:Prognosis; D011859:Radiography; D012189:Retrospective Studies; D016019:Survival Analysis