Anti-E in pregnancy.
Since the introduction of anti-Rhesus (Rh) D prophylaxis for RhD-negative women, other Rh and non-Rh red cell alloantibodies have become relatively more important and are now responsible for the greater proportion of haemolytic disease of the newborn. Anti-C and anti-E are the most commonly implicated non-D Rh antibodies in the pathogenesis of haemolytic disease of the newborn'. In 1977 Pepperell et al. reported the outcome of 44 women with anti-E. This is the only published series that investigates the implications of anti-E during pregnancy. The present report presents a retrospective study of the outcome of 122 pregnancies in which anti-E was the sole alloantibody detected.
Moran
P
P
Department of Obstetrics and Gynaecology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.
Robson
S C
SC
Reid
M M
MM
D004899:Erythroblastosis, Fetal / Q000175:diagnosis*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D007518:Isoantibodies / Q000097:blood*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis*; D011256:Pregnancy Outcome; D012189:Retrospective Studies
D006454:Hemoglobins; D007518:Isoantibodies