[A case of resected squamous cell carcinoma of the lung complicated with sarcoidosis].
A 64-year-old man with uveitis was admitted to our hospital for detailed investigation of an abnormal shadow on his chest X-ray. Chest radiography and computed tomography of the chest showed mediastinal lymphadenopathy and a tumor shadow in the left hilum. Transbronchial tumor biopsy revealed squamous cell carcinoma. Left upper lobectomy and drainage of bilateral hilar and mediastinal lymph nodes were performed. Histopathological examination revealed the coexistence of squamous cell carcinoma with many non-caseating epithelioid cell granulomas in all hilar and mediastinal drainage lymph nodes, but no metastasis. Non-caseating epithelioid cell granulomas were also seen in the interstitium and alveolar spaces. Coexistence of sarcoidosis and lung cancer in the same patient is not common, and only 29 cases, including ours, have been reported. This case also provides the concept that surgical tumor resection should be considered even if bilateral mediastinal lymphadenopathy is found in a case of lung cancer complicated with sarcoidosis.
Muramatsu
M
M
Department of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Kuriyama
M
M
Takahashi
K
K
Miyamoto
H
H
Uekusa
T
T
Danbara
T
T
Fukuchi
Y
Y
D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology* / Q000601:surgery; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D012507:Sarcoidosis / Q000150:complications*