Sexual side effects of antidepressant drugs.
Sexual functioning often suffers during depression, although depressed people continue to value sex. Many popular antidepressants further impair sexual functioning, with highly serotonergic agents affecting orgasm and libido prominently. This paper addresses clinical assessment of sexual side effects from antidepressant drugs and reviews treatment strategies, including purported antidotes. We pay particular attention to sildenafil, on which there are impressive data and ongoing controlled studies.
Gelenberg
A J
AJ
Department of Psychiatry, Arizona Health Sciences Center, 1501 North Campbell Avenue, PO Box 245002, Tucson, AZ 85724-5002, USA. alang@u.arizona.edu
Delgado
P
P
Nurnberg
H G
HG
D000928:Antidepressive Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D010348:Patient Care Team; D018490:Serotonin Agents / Q000009:adverse effects / Q000627:therapeutic use; D020018:Sexual Dysfunctions, Psychological / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology
D000928:Antidepressive Agents; D018490:Serotonin Agents