Vermiculine: a diolide with immunoregulatory activity.
Vermiculine (1), is a macrodiolide which displays a selective effect on certain reactions of cellular immunity. This paper summarizes data on its biological activity, isolation, microbial production, chemical properties and methods for its synthesis.
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Slovakofarma a.s., Hlohovec, and Faculty of Chemistry, Technical University, Bratislava, Slovakia.
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D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
D000903:Antibiotics, Antineoplastic; D000970:Antineoplastic Agents; D007783:Lactones; C009650:vermiculine