title: alpha4 integrin is expressed in a subset of cranial neural crest cells and in epicardial progenitor cells during early mouse development.
abstract: By RNA in situ hybridization and immunohistochemical analyses of early stage mouse embryos, we find that alpha 4 integrin gene is expressed in migratory cranial neural crest cells originating from the presumptive forebrain, midbrain, and rhombomeres 1 and 2 of the presumptive hindbrain. alpha 4 is also expressed in epicardial progenitor cells in the septum transversum that migrate to the heart.
authors: Department of Cell Biology and Anatomy, The Johns Hopkins University School of Medicine, baltimore, MD 21205, USA.
authors: K A
authors: KA
authors: Pinco
authors: S
authors: S
authors: Liu
authors: J T
authors: JT
authors: Yang
mesh_terms: D000818:Animals; D015703:Antigens, CD / Q000096:biosynthesis*; D004622:Embryo, Mammalian / Q000378:metabolism; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D039441:Integrin alpha4; D008636:Mesencephalon / Q000196:embryology; D051379:Mice; D009432:Neural Crest / Q000196:embryology*; D010496:Pericardium / Q000196:embryology*; D016548:Prosencephalon / Q000196:embryology; D012313:RNA / Q000378:metabolism; D012249:Rhombencephalon / Q000196:embryology; D013234:Stem Cells / Q000378:metabolism*; D013997:Time Factors
chemical_list: D015703:Antigens, CD; D039441:Integrin alpha4; D012313:RNA