The coronavirus infectious bronchitis virus nucleoprotein localizes to the nucleolus.
The coronavirus nucleoprotein (N) has been reported to be involved in various aspects of virus replication. We examined by confocal microscopy the subcellular localization of the avian infectious bronchitis virus N protein both in the absence and in the context of an infected cell and found that N protein localizes both to the cytoplasmic and nucleolar compartments.
Hiscox
J A
JA
School of Animal and Microbial Sciences, University of Reading, Reading, Berkshire RG6 6AJ, United Kingdom. j.a.hiscox@reading.ac.uk
Wurm
T
T
Wilson
L
L
Britton
P
P
Cavanagh
D
D
Brooks
G
G
D000595:Amino Acid Sequence; D000818:Animals; D002466:Cell Nucleolus / Q000737:chemistry*; D002522:Chlorocebus aethiops; D003593:Cytoplasm / Q000737:chemistry; D001351:Infectious bronchitis virus / Q000737:chemistry*; D018613:Microscopy, Confocal; D008969:Molecular Sequence Data; D019590:Nucleocapsid Proteins / Q000032:analysis*; D014709:Vero Cells
D019590:Nucleocapsid Proteins