IQ scores of treatment-resistant schizophrenia patients before and after the onset of the illness.
In this study we examined the correlations of actual pre-morbid IQ scores (obtained from routine educational assessments) and estimated current IQ scores in 27 treatment-resistant schizophrenia patients. Pre-morbid (mean = 93) and current (mean = 83) IQ scores were significantly correlated (r = 0.807, P < 0.0001), while duration of illness (10-40 years) was unrelated to the magnitude of IQ score decline (r = -0.103, P = 0.575). These data suggest that pre-morbid IQ test scores are highly predictive of post-morbid scores.
Sheitman
B B
BB
Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA. Bsheitman@css.unc.edu
Murray
M G
MG
Snyder
J A
JA
Silva
S
S
Goldman
R
R
Chakos
M
M
Volavka
J
J
Lieberman
J A
JA
D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D004311:Double-Blind Method; D004351:Drug Resistance; D005260:Female; D006801:Humans; D007360:Intelligence; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy*; D014888:Wechsler Scales
D014150:Antipsychotic Agents