title: Pets and cockroaches: two increasing causes of respiratory allergy in indoor environments. Characteristics of airways sensitization and prevention strategies.
abstract: The increasing prevalence of allergic sensitization to indoor allergens such as dust mites, pets and cockroaches is the result of the changes in indoor environments induced by human activities. The Westernized lifestyle and the increasing time spent indoors determine a reduction in natural air ventilation and, consequently, higher levels of allergen concentrations and longer exposure to allergens. The major cat allergen Fel d 1 is carried by small-dimension particles (< 5 microm diameter) that readily become airborne and persist immodified for a long time. Fel d 1 must be considered a ubiquitous allergen because it has been found in indoor environments and even in public places where a cat has never been kept. Recent research has demonstrated that clothing of cat owners may contribute to the dispersal of Fel d 1 in cat-free environments. Therefore, washing Fel d 1-contaminated clothes should be considered a simple and effective method for removing this allergen from clothing and, consequently, reducing the risk of Fel d 1 dispersion. Cockroach allergens constitute another important cause of environment-related respiratory allergy and may trigger asthma exacerbations in sensitized individuals. In the prevention of cockroach allergy, the use of chemical agents associated with an intensive vacuum cleaning of indoor environments is an important tool in removing cockroach material containing allergenic proteins. Early recognition of allergy-predisposed babies, monitoring indoor allergens and adequate strategies of allergen avoidance are likely to be important means for reducing the prevalence of bronchial asthma.
authors: Department of Chest Diseases, A. Cardarelli Hospital, Naples, Italy.
authors: G
authors: G
authors: Liccardi
authors: M
authors: M
authors: Cazzola
authors: M
authors: M
authors: D'Amato
authors: G
authors: G
authors: D'Amato
mesh_terms: D000485:Allergens / Q000009:adverse effects* / Q000032:analysis; D000818:Animals; D016535:Bronchial Hyperreactivity / Q000209:etiology* / Q000517:prevention & control; D002415:Cats / Q000276:immunology*; D003058:Cockroaches / Q000276:immunology*; D004285:Dogs / Q000276:immunology*; D004391:Dust / Q000032:analysis; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology* / Q000517:prevention & control; D007231:Infant, Newborn; D015995:Prevalence; D012307:Risk Factors
chemical_list: D000485:Allergens; D004391:Dust