Structural genomics in the biotechnology sector.
Commercial efforts in structural genomics focus on providing to pharmaceutical customers information that relates to the suitability of specific proteins as drug targets and the informed selection and refinement of lead compounds generated by high-throughput screening and rational approaches. These efforts follow a variety of business models and are impacted by activities in the public domain, recent technological advances, and the changing intellectual property landscape.
Dry
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Structural GenomiX Inc, San Diego, California 92121, USA.
McCarthy
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Harris
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D000818:Animals; D001709:Biotechnology / Q000379:methods*; D019295:Computational Biology / Q000379:methods; D018360:Crystallography, X-Ray; D019992:Databases as Topic; D015195:Drug Design; D004345:Drug Industry / Q000379:methods; D023281:Genomics / Q000379:methods; D006801:Humans; D020407:Internet; D051379:Mice; D008817:Mice, Mutant Strains; D008958:Models, Molecular; D017149:Private Sector; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D017150:Public Sector; D013329:Structure-Activity Relationship
D011506:Proteins