Sarcomatoid hepatocellular carcinoma with chondroid variant: case report with immunohistochemical findings.
A case of sarcomatoid hepatocellular carcinoma (HCC) with a chondroid variant in a 72-year-old woman is reported. Histologically, the tumor consisted of typical HCC of adult type, with an adenocarcinoma-like structure and a sarcomatoid component containing multinodular chondroid foci. Transition from carcinoma to sarcomatoid component was observed. The cells containing mucus were extremely few in adenocarcinoma-like structures. Immunohistochemically, other than typical HCC, some of the chondroid cells, adenocarcinoma-like cells and sarcomatoid cells were positive for alpha-fetoprotein.
Fu
Y
Y
First Department of Pathology, Kagawa Medical University, Kagawa, Japan.
Kobayashi
S
S
Kushida
Y
Y
Saoo
K
K
Haba
R
R
Mori
S
S
Miki
H
H
Ohmori
M
M
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D006528:Carcinoma, Hepatocellular / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D002813:Chondrosarcoma / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D004564:Electrocoagulation; D017809:Fatal Outcome; D005260:Female; D006498:Hepatectomy; D006801:Humans; D007124:Immunoenzyme Techniques; D008113:Liver Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D008872:Microwaves / Q000627:therapeutic use; D009363:Neoplasm Proteins / Q000032:analysis
D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins