title: Fetal and maternal outcomes in Indo-Asian compared to caucasian women with diabetes in pregnancy.
abstract: Maternal and fetal complications are increased when pregnancy is complicated by diabetes, and this may be further influenced by racial and cultural differences. We examined fetal and maternal outcomes in Indo-Asian and Caucasian women attending the same antenatal diabetes service to see if there were any differences. Women with diabetes mellitus (type 1, type 2 and gestationally-acquired disease) complicating pregnancy, registered at the combined diabetes/antenatal clinic of this University teaching hospital over the period 1990-1998 were included. Fetal outcomes examined were miscarriage <24 weeks, stillbirths, neonatal deaths up to 28 days of life, perinatal mortality, congenital malformations and size for gestational age. Maternal outcomes examined were rates of caesarean section and vaginal deliveries, and number of pre-term deliveries <37 completed weeks of gestation. Outcomes for Indo-Asian and Caucasian women were similar, with a take-home baby rate of 96% and 92%, respectively. There was no perinatal mortality in Indo-Asian women, who were more likely to have a vaginal delivery and less likely to have a baby large for gestational age. Pregnancies complicated by type 2 diabetes in both groups pose the greatest threat to a successful pregnancy outcome. Indo-Asian and Caucasian women attending the same antenatal diabetes service have comparable outcomes. Attendance for pre-pregnancy care needs to be encouraged to combat the high early pregnancy loss and congenital malformation rate identified, particularly in those with type 2 disease, irrespective of ethnicity.
authors: Department of Diabetic Medicine, University Hospital Trust, University of Birmingham, Birmingham, UK. Fidelma.Dunne@University-b.wmids.nhs.uk
authors: F P
authors: FP
authors: Dunne
authors: P A
authors: PA
authors: Brydon
authors: M
authors: M
authors: Proffitt
authors: T
authors: T
authors: Smith
authors: H
authors: H
authors: Gee
authors: R L
authors: RL
authors: Holder
mesh_terms: D001459:Bangladesh / Q000208:ethnology; D001724:Birth Weight; D036861:Delivery, Obstetric; D003922:Diabetes Mellitus, Type 1 / Q000208:ethnology; D003924:Diabetes Mellitus, Type 2 / Q000208:ethnology; D016640:Diabetes, Gestational / Q000208:ethnology*; D005260:Female; D005313:Fetal Death / Q000208:ethnology; D006801:Humans; D007194:India / Q000208:ethnology; D007226:Infant Mortality; D007231:Infant, Newborn; D010154:Pakistan / Q000208:ethnology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000208:ethnology; D011256:Pregnancy Outcome / Q000208:ethnology*; D011254:Pregnancy in Diabetics / Q000208:ethnology*; D006113:United Kingdom; D044465:White People