title: Optimization of contrast-enhanced MR angiography of the hands with a timing bolus and elliptically reordered 3D pulse sequence.
abstract: Our objective was to optimize bolus administration and sequence setting in gadolinium-enhanced magnetic resonance (MR) angiography of the hands. Elliptically reordered three-dimensional (3D) spoiled gradient-echo sequence with non-slab-selective radio frequency excitation was optimized according to the measurements of arterial and venous time-signal curves in 21 patients. Great variations in bolus arrival time and arterio-venous transit time could be observed. In most patients high-quality arterial depiction could be obtained with minor venous contamination. Contrast-to-noise, spatial resolution, and selective arterial filling is still a challenge for 3D MR angiography of the hand but can be optimized using Gadolinium-BOPTA and a dedicated pulse sequence setting with exact bolus timing.
authors: Department of Diagnostic Radiology, University of Freiburg, Germany. winterja@ruf.uni-freiburg.de
authors: J T
authors: JT
authors: Winterer
authors: K
authors: K
authors: Scheffler
authors: G
authors: G
authors: Paul
authors: M
authors: M
authors: Hauer
authors: O
authors: O
authors: Schäfer
authors: C
authors: C
authors: Altehoefer
authors: J
authors: J
authors: Laubenberger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001158:Arteries / Q000473:pathology; D016477:Artifacts; D002648:Child; D003287:Contrast Media / Q000008:administration & dosage; D004617:Embolism / Q000175:diagnosis; D005260:Female; D005682:Gadolinium / Q000008:administration & dosage; D006225:Hand / Q000098:blood supply*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008536:Meglumine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage; D011928:Raynaud Disease / Q000175:diagnosis; D013997:Time Factors
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C064572:gadobenic acid; D008536:Meglumine; D005682:Gadolinium