An unusual seven-bond H-H spin coupling
A through-space, seven-bond (1)H-(1)H coupling has been observed in tiliacorinine (1) caused by the close spacial proximity of two aromatic protons that are located in different benzene rings which are separated by two sp(3) carbons. Results from DQF-COSY and NOESY NMR experiments, as well as molecular modeling, reveal that the two protons are unusually close to one another in space.
Bhacca
NS
Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, USA.
Juneau
GP
Lankin
DC
Mukherjee
B
Seal
T
Escobedo
JO
Strongin
RM