Merging the old skeletal biology with the new. I. Intramembranous ossification, endochondral ossification, ectopic bone, secondary cartilage, and pathologic considerations.
Skeletogenesis and chondrogenesis result from a sequence of events involving epithelial-mesenchymal interaction, condensation, and differentiation. Types of bone and cartilage formation include: (1) intramembranous ossification, (2) endochondral ossification, (3) combined endochondral and intramembranous ossification, (4) heterotopic bone and cartilage formation, and (5) secondary cartilage formation. Pathologic conditions with bone and cartilage include: (1) benign and malignant tumors and (2) reactive osseous and cartilaginous metaplasia.
Cohen
M M
MM
Department of Oral & Maxillofacial Sciences, Dalhousie University, Halifax, Nova Scotia, Canada. remaclea@is.dal.ca
D000818:Animals; D001847:Bone Diseases / Q000503:physiopathology; D001859:Bone Neoplasms / Q000503:physiopathology; D001842:Bone and Bones / Q000473:pathology / Q000502:physiology*; D002356:Cartilage / Q000473:pathology / Q000502:physiology*; D020219:Chondrogenesis; D002828:Choristoma / Q000473:pathology*; D003240:Connective Tissue Diseases / Q000503:physiopathology; D006801:Humans; D009372:Neoplasms, Connective Tissue / Q000503:physiopathology; D010012:Osteogenesis