[Radiation therapy in two cats with pituitary tumors].
Two cats with large pituitary neoplasms (adenoma and adenocarcinoma) were treated with fractionated radiation therapy. Total doses of 40 Gy, respectively 36 Gy, were applied in 10 fractions of 4 Gy, and 3.6 Gy respectively. Side effects were minimal and transient. Anesthesia was well tolerated. Improvement of clinical signs could be observed during radiation therapy in both cats. One cat had a complete, the other a partial tumor response. One cat (suspicion of adenoma) was euthanized 1 3/4 years after therapy due to unrelated disease. No tumor was found on histopathology, however a small focal necrosis of brain tissue in the irradiated field was observed. The second animal with a pituitary adenocarcinoma was euthanized because of tumor recurrence 1 1/2 years after therapy. Radiation therapy was effective, despite the low total doses of radiation applied.
Kaser-Hotz
B
B
Veterinär-Chirurgische Klinik, Universität Zürich.
Reiner
B
B
Hauser
B
B
Arnold
P
P
Lieb
A
A
Cordt
I
I
Lang
J
J
Blattmann
H
H
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000662:veterinary*; D000818:Animals; D002371:Cat Diseases / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D002415:Cats; D005260:Female; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000662:veterinary*; D014057:Tomography, X-Ray Computed / Q000662:veterinary