Erythema multiforme: a case with unusual histopathological features.
A 14-year-old boy presented with widespread cutaneous and mucosal lesions clinically consistent with erythema multiforme. He gave a history of previous episodes of a similar eruption. Histological examination of a representative lesion showed changes consistent with erythema multiforme. It also, however, contained large numbers of eosinophils, forming a dermal interstitial infiltrate and epidermal microabscesses. The full blood examination showed a persistent eosinophilia. The appearances initially confused two experienced dermatopathologists.
Wells
J M
JM
Royal Brisbane Hospital, Queensland, Australia. cjohnsto@bigpond.net.au
Weedon
D
D
Muir
J B
JB
D000212:Acyclovir / Q000008:administration & dosage; D000293:Adolescent; D001707:Biopsy, Needle; D004359:Drug Therapy, Combination; D004892:Erythema Multiforme / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology*; D019085:Fluorescent Antibody Technique, Direct; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage
D011239:Prednisolone; D000212:Acyclovir