title: 'Upenamide: An unprecedented macrocyclic alkaloid from the Indonesian sponge Echinochalina sp.
abstract: 'Upenamide (1) represents a new class of macrocyclic marine alkaloid possessing both spirooxaquinolizidinone and hemiaminal ring systems. It was isolated from the Indonesian sponge Echinochalina sp. The gross structure of 1 was elucidated by spectroscopic methods and accurate mass measurements. A suggestion is made as to its biogenetic origin.
authors: Department of Chemistry, University of Hawai'i at Manoa, Honolulu, Hawaii 96822-2275, USA.
authors: J I
authors: JI
authors: Jiménez
authors: G
authors: G
authors: Goetz
authors: C M
authors: CM
authors: Mau
authors: W Y
authors: WY
authors: Yoshida
authors: P J
authors: PJ
authors: Scheuer
authors: R T
authors: RT
authors: Williamson
authors: M
authors: M
authors: Kelly
mesh_terms: D000818:Animals; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D011807:Quinolizines / Q000737:chemistry / Q000302:isolation & purification*; D013141:Spiro Compounds / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D011807:Quinolizines; D013141:Spiro Compounds; C418125:upenamide