Improved detection of the T(341)C polymorphism in human N-acetyltransferase (NAT2) gene by using two complementary PCR-RFLP methods: better than automated DNA sequencing for detection of heterozygotes.
Simsek
M
M
Department of Biochemistry, College of Medicine, Sultan Qaboos University, Muscat, Oman.
Tanira
M O
MO
Al-Baloushi
K A
KA
Al-Barwani
H S
HS
Lawatia
K M
KM
Bayoumi
R A
RA
D000483:Alleles; D001191:Arylamine N-Acetyltransferase / Q000235:genetics*; D015252:Deoxyribonucleases, Type II Site-Specific / Q000378:metabolism; D005838:Genotype; D006579:Heterozygote; D006801:Humans; D009850:Oman; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D017422:Sequence Analysis, DNA / Q000379:methods*
D001191:Arylamine N-Acetyltransferase; C027908:endodeoxyribonuclease DdeI; C052380:endodeoxyribonuclease NcoI; D015252:Deoxyribonucleases, Type II Site-Specific