title: The frequency of Candida parapsilosis in onychomycosis. An epidemiological survey in Israel.
abstract: Candida albicans is regarded as the major pathogen in yeast-induced onychomycosis. Based on our impression of an increasing prevalence of Candida parapsilosis in this disease, we examined the data of two mycology laboratories in the same geographic location, from 1994 to 1996 in one (centre A) and for 1995 (6 months) in the other (centre B). A total of 954 and 230 toenails and 621 and 190 fingernails, respectively, underwent KOH microscopy and culture studies in each centre. Positive findings were noted in 45 and 65% of the toenails and 44 and 72% of the fingernails, respectively. In the toenails, Candida spp. were found in 22 and 15%, respectively, and in the fingernails, in 77 and 63%, respectively. The most frequent Candida species was C. parapsilosis (39.5% in toenails, 36.7% in fingernails), followed by C. albicans (19.5% in toenails, and 34.4% in fingernails). These results demonstrate a higher frequency of isolation of C. parapsilosis compared with C. albicans in onychomycosis. This might have important therapeutic implications.
authors: Department of Dermatology, Rabin Medical Center, Petah Tiqva, Israel.
authors: R
authors: R
authors: Segal
authors: A
authors: A
authors: Kimchi
authors: A
authors: A
authors: Kritzman
authors: R
authors: R
authors: Inbar
authors: Z
authors: Z
authors: Segal
mesh_terms: D002175:Candida / Q000145:classification / Q000302:isolation & purification*; D002177:Candidiasis / Q000453:epidemiology* / Q000382:microbiology; D003470:Culture Media; D005260:Female; D005533:Foot Dermatoses / Q000453:epidemiology / Q000382:microbiology; D006229:Hand Dermatoses / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D008297:Male; D014009:Onychomycosis / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D003470:Culture Media