title: Rates of psychiatric disorders in a clinical study group of adolescents with extreme obesity and in obese adolescents ascertained via a population based study.
abstract: OBJECTIVE
  To compare rates of DSM-IV psychiatric disorders between (1) a clinical study group of extremely obese adolescents and young adults, (2) gender-matched population-based obese controls and (3) a population-based control group of the same age range.
  
  
  METHODS
  Rates of psychiatric disorders were assessed in (1) the clinical study group of obese adolescents and (2) the population based sample of obese adolescents, and compared to (3) a large population-based control group using a standardized psychiatric interview.
  
  
  METHODS
  (1) Clinical study group: 30 female and 17 male extremely obese adolescents and young adults (age range: 15-21 y; mean BMI:42.4 kg/m2). (2) Thirty females and 17 males with the highest BMI (age range 15-21 y; mean BMI: 29.8 kg/m2) of a population-based control group encompassing 1655 (805 males) adolescents and young adults. (3) The population based control group excluding the 30 females and 17 males with the highest BMI (n = 1608; 788 males).
  
  
  METHODS
  Munich-Composite International Diagnostic Interview (M-CIDI) allowing for DSM-IV diagnoses.
  
  
  RESULTS
  High rates of mood, anxiety, somatoform and eating disorders were detected in the clinical sample of obese adolescents which exceeded those observed in population controls (all P-values < 0.01). Rates between population-based obese adolescents and young adults and population controls did not differ. In most patients the psychiatric disorders set in after onset of obesity. 57% and 35% of the female and male patients, respectively, reported eating binges with lack of control. However, less than one-half of these patients qualified for a DSM-IV diagnosis of an eating disorder.
  
  
  CONCLUSIONS
  Extremely obese adolescents and young adults who seek long-term inpatient treatment have a high lifetime prevalence for affective, anxiety, somatoform and eating disorders. Because the mean BMI of the clinical study group was considerably higher than that of the obese population controls, we were not able to clarify whether the high rate of psychopathology in the study group was related to the extreme obesity or to their treatment-seeking behavior.
authors: Department of Child and Adolescent Psychiatry of the University of Marburg, Germany.
authors: B
authors: B
authors: Britz
authors: W
authors: W
authors: Siegfried
authors: A
authors: A
authors: Ziegler
authors: C
authors: C
authors: Lamertz
authors: B M
authors: BM
authors: Herpertz-Dahlmann
authors: H
authors: H
authors: Remschmidt
authors: H U
authors: HU
authors: Wittchen
authors: J
authors: J
authors: Hebebrand
mesh_terms: D000273:Adipose Tissue; D000293:Adolescent; D000328:Adult; D001008:Anxiety Disorders / Q000453:epidemiology; D001823:Body Composition; D015992:Body Mass Index; D003863:Depression / Q000453:epidemiology; D001068:Feeding and Eating Disorders / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000150:complications / Q000453:epidemiology*; D019964:Mood Disorders / Q000453:epidemiology; D009765:Obesity / Q000523:psychology*; D009767:Obesity, Morbid / Q000523:psychology*; D013001:Somatoform Disorders / Q000453:epidemiology; D013997:Time Factors