title: Efficacy and safety of the new high-energy 30-minute transurethral microwave thermotherapy: results of 1-year follow-up in a multicenter study.
abstract: OBJECTIVE
  To assess the efficacy and durability of a new 30-minute algorithm for high-energy transurethral microwave thermotherapy (TUMT, Prostasoft 3.5) in the treatment of men with lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia.
  
  
  METHODS
  A total of 167 men (mean age 67 years) with bothersome LUTS were treated with the new TUMT protocol. Evaluation included assessment of the short- and long-term objective and subjective outcome measures of this treatment.
  
  
  RESULTS
  The treatment is well tolerated. The International Prostate Symptom Score improved from a mean of 19.2 at baseline to 7.9 at 12 months after treatment. Maximum urinary flow improved from 8.9 to 16.4 mL/s at 12 months. Mean duration of catheterization was 16.1 days. Urodynamic evaluation showed a change from the obstructed to the nonminimally obstructed zone. There were no serious complications.
  
  
  CONCLUSIONS
  High-energy TUMT using the new high-dose Prostasoft 3.5 protocol appears to be a safe, effective, and durable treatment. The faster procedure improves tolerance of the treatment. Subjective and objective improvements were significant and the treatment-related morbidity low.
authors: Department of Urology, University Medical Center St. Radboud, Nijmegen, The Netherlands.
authors: J J
authors: JJ
authors: de La Rosette
authors: M P
authors: MP
authors: Laguna
authors: G
authors: G
authors: Pace
authors: B B
authors: BB
authors: Kortmann
authors: O
authors: O
authors: Selvaggio
authors: F M
authors: FM
authors: Debruyne
authors: F P
authors: FP
authors: Selvaggi
mesh_terms: D000368:Aged; D005500:Follow-Up Studies; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D011470:Prostatic Hyperplasia / Q000503:physiopathology / Q000628:therapy*; D011788:Quality of Life; D012449:Safety; D016896:Treatment Outcome; D014521:Urethra; D014563:Urodynamics