title: PROP (6-n-Propylthiouracil) tasting and sensory responses to caffeine,sucrose, neohesperidin dihydrochalcone and chocolate.
abstract: The genetically determined ability to taste 6-n-propylthiouracil (PROP) has been linked with lowered acceptance of some bitter foods. Fifty-four women, aged 18-30 years, tasted and rated PROP-impregnated filter paper and seven solutions of PROP. Summed bitterness intensity ratings for PROP solutions determined PROP taster status. Respondents also tasted five sucrose and seven caffeine solutions, as well as seven solutions each of caffeine and PROP that had been sweetened with 0.3 mmol/l neohesperidin dihydrochalcone (NHDC). Respondents also rated three kinds of chocolate using 9-point category scales. PROP tasters rated caffeine solutions as more bitter than did non-tasters and liked them less. PROP tasters did not rate either sucrose or NHDC as more sweet. The addition of NHDC to PROP and caffeine solutions suppressed bitterness intensity more effectively for tasters than for non-tasters and improved hedonic ratings among both groups. PROP tasters and non-tasters showed the same hedonic response to sweetened caffeine solutions and did not differ in their sensory responses to chocolate. Genetic taste markers may have only a minor impact on the consumption of such foods as sweetened coffee or chocolate.
authors: Nutritional Sciences Program, University of Washington, Seattle, WA 98195-353410, USA.
authors: A
authors: A
authors: Ly
authors: A
authors: A
authors: Drewnowski
mesh_terms: D000293:Adolescent; D000328:Adult; D002099:Cacao; D002110:Caffeine; D002599:Chalcone / Q000031:analogs & derivatives; D047188:Chalcones; D004435:Eating / Q000502:physiology; D005260:Female; D005518:Food Preferences / Q000502:physiology; D006569:Hesperidin / Q000031:analogs & derivatives; D006801:Humans; D011441:Propylthiouracil; D012996:Solutions; D013395:Sucrose; D013549:Sweetening Agents; D013649:Taste / Q000235:genetics / Q000502:physiology*
chemical_list: D047188:Chalcones; D012996:Solutions; D013549:Sweetening Agents; D002110:Caffeine; C013613:neohesperidin dihydrochalcone; D013395:Sucrose; D002599:Chalcone; D011441:Propylthiouracil; D006569:Hesperidin