title: Periurethral transurethral microwave thermotherapy for the treatment of benign prostatic hyperplasia: an interim 1-year safety and efficacy analysis using the thermatrx TMx-2000.
abstract: Transurethral microwave thermotherapy (TUMT) represents an accepted minimally invasive approach to the management of patients with benign prostatic hyperplasia (BPH). The TherMatrx TMx-2000 represents a further evolution in TUMT technique. This device uses periurethral transurethral microwave thermotherapy (P-TUMT) technology to directly target the BPH tissue adjacent to the prostatic urethra by using a catheter without a urethral-cooling surface. This article provides a technical review of the device and describes the results of a randomized, controlled multicenter study of P-TUMT for the treatment of symptomatic BPH. A discussion of the physiologic effects of P-TUMT is presented and compared to conventional TUMT. A comparison of P-TUMT to contemporary TUMT series in relation to efficacy and complications is also described. This study concludes that P-TUMT using the TherMatrx TMx-2000 device represents a minimally invasive, efficacious, and well-tolerated treatment for symptomatic BPH.
authors: Department of Urology, Loyola University Medical Center Maywood, Illinois, USA.
authors: D M
authors: DM
authors: Albala
authors: T M
authors: TM
authors: Turk
authors: B R
authors: BR
authors: Fulmer
authors: F
authors: F
authors: Koleski
authors: G
authors: G
authors: Andriole
authors: B E
authors: BE
authors: Davis
authors: G R
authors: GR
authors: Eure
authors: J N
authors: JN
authors: Kabalin
authors: J
authors: J
authors: Lingeman
authors: J
authors: J
authors: Nuzzarello
authors: C
authors: C
authors: Sundaram
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000628:therapy*; D012449:Safety