title: Scintigraphic evaluation of calcinosis in juvenile dermatomyositis with Tc-99m MDP.
abstract: Two children with juvenile dermatomyositis and extensive, debilitating soft tissue calcifications are described. Whole-body bone scans with Tc-99m MDP were performed in both cases before and during specific treatment for the calcinosis. Baseline studies showed marked tracer localization in the soft tissues and provided an objective baseline assessment of the extent of the soft tissue calcifications. Follow-up studies showed gradual clearance of the extraskeletal uptake and were useful in monitoring the therapeutic response. These cases show that skeletal scintigraphy can function as a useful auxiliary tool to evaluate calcinosis in children with juvenile dermatomyositis.
authors: Department of Nuclear Medicine, Rabin Medical Center, Petach-Tikva, Israel. barsev@isdn.net.il
authors: Z
authors: Z
authors: Bar-Sever
authors: M
authors: M
authors: Mukamel
authors: L
authors: L
authors: Harel
authors: R
authors: R
authors: Hardoff
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging; D002114:Calcinosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D002675:Child, Preschool; D003882:Dermatomyositis / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate; D013997:Time Factors
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate