title: The TRANSFAC system on gene expression regulation.
abstract: The TRANSFAC database on transcription factors and their DNA-binding sites and profiles (http://www.gene-regulation.de/) has been quantitatively extended and supplemented by a number of modules. These modules give information about pathologically relevant mutations in regulatory regions and transcription factor genes (PathoDB), scaffold/matrix attached regions (S/MARt DB), signal transduction (TRANSPATH) and gene expression sources (CYTOMER). Altogether, these distinct database modules constitute the TRANSFAC system. They are accompanied by a number of program routines for identifying potential transcription factor binding sites or for localizing individual components in the regulatory network of a cell.
authors: Gesellschaft für Biotechnologische Forschung mbH, Mascheroder Weg 1, D-38124 Braunschweig, Germany. ewi@gbf.de
authors: E
authors: E
authors: Wingender
authors: X
authors: X
authors: Chen
authors: E
authors: E
authors: Fricke
authors: R
authors: R
authors: Geffers
authors: R
authors: R
authors: Hehl
authors: I
authors: I
authors: Liebich
authors: M
authors: M
authors: Krull
authors: V
authors: V
authors: Matys
authors: H
authors: H
authors: Michael
authors: R
authors: R
authors: Ohnhäuser
authors: M
authors: M
authors: Prüss
authors: F
authors: F
authors: Schacherer
authors: S
authors: S
authors: Thiele
authors: S
authors: S
authors: Urbach
mesh_terms: D001665:Binding Sites; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D016208:Databases, Factual; D005786:Gene Expression Regulation; D020407:Internet; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism
chemical_list: D004268:DNA-Binding Proteins; D014157:Transcription Factors