title: Protein production: feeding the crystallographers and NMR spectroscopists.
abstract: Protein purification efforts for structural genomics will focus on automation for the readily-expressed proteins, and process development for the more difficult ones, such as membrane proteins. Thousands of proteins are expected to be produced in the next few years. The purified proteins will be valuable reagents for the entire research community.
authors: Ontario Cancer Institute, Toronto, Canada. aled.edwards@utoronto.ca
authors: A M
authors: AM
authors: Edwards
authors: C H
authors: CH
authors: Arrowsmith
authors: D
authors: D
authors: Christendat
authors: A
authors: A
authors: Dharamsi
authors: J D
authors: JD
authors: Friesen
authors: J F
authors: JF
authors: Greenblatt
authors: M
authors: M
authors: Vedadi
mesh_terms: D000818:Animals; D003001:Cloning, Molecular; D018360:Crystallography, X-Ray; D015870:Gene Expression; D008565:Membrane Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification; D019906:Nuclear Magnetic Resonance, Biomolecular; D014176:Protein Biosynthesis; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification; D011786:Quality Control; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification / Q000592:standards; D012371:Robotics
chemical_list: D008565:Membrane Proteins; D011506:Proteins; D011993:Recombinant Fusion Proteins