title: Large, deep high-grade extremity sarcomas: when is a myocutaneous flap reconstruction necessary?
abstract: The surgical treatment of large, deep high-grade extremity soft tissue sarcomas frequently produces a significant tissue defect. In addition, the management of the surgical wound is often further complicated by preoperative radiation or adjuvant therapies. The use of either pedicled or free myocutaneous flaps allows for more rapid and predictable wound healing in this situation. Myocutaneous flaps provide well-vascularized coverage of lost tissue volume, exposed vital structures, and prosthetic reconstruction materials. When harvested from unirradiated sites, flap coverage can overcome the detrimental effects of radiation therapy and chemotherapy on postoperative wound healing. Reconstruction of the soft tissue defect may also improve patient satisfaction with aesthetic issues. The use of innervated myocutaneous flaps can even address the functionality of the extremity following resection of major muscle groups. Myocutaneous flaps are an extremely versatile option for reconstruction in the treatment of large, deep high-grade extremity soft tissue sarcomas.
authors: Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
authors: J M
authors: JM
authors: Kane
authors: J F
authors: JF
authors: Gibbs
authors: B E
authors: BE
authors: McGrath
authors: T R
authors: TR
authors: Loree
authors: W G
authors: WG
authors: Kraybill
mesh_terms: D000328:Adult; D005121:Extremities / Q000601:surgery; D005260:Female; D006801:Humans; D019651:Plastic Surgery Procedures / Q000379:methods; D012509:Sarcoma / Q000473:pathology / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000473:pathology / Q000601:surgery*; D013524:Surgical Flaps / Q000098:blood supply / Q000294:innervation