The apical organelles of malaria merozoites: host cell selection, invasion, host immunity and immune evasion.
Malaria is caused by protozoan parasites belonging to the phylum Apicomplexa. These obligate intracellular parasites depend on the successful invasion of an appropriate host cell for their survival. This article is a broad overview of the molecular strategies employed by the merozoite, an invasive form of the malaria parasite, to successfully invade a suitable red blood cell.
Preiser
P
P
Division of Parasitology, The National Institute for Medical Research, The Ridgeway, Mill Hill, NW7 1AA, London, UK. ppreise@nimr.mrc.ac.uk
Kaviratne
M
M
Khan
S
S
Bannister
L
L
Jarra
W
W
D000818:Animals; D000913:Antibodies, Protozoan / Q000096:biosynthesis; D000953:Antigens, Protozoan / Q000276:immunology; D016782:Apicomplexa / Q000276:immunology* / Q000502:physiology* / Q000648:ultrastructure; D004912:Erythrocytes / Q000469:parasitology; D008288:Malaria / Q000276:immunology* / Q000469:parasitology*; D008954:Models, Biological; D015388:Organelles / Q000737:chemistry / Q000648:ultrastructure; D010963:Plasmodium falciparum / Q000276:immunology / Q000502:physiology / Q000648:ultrastructure; D011528:Protozoan Infections / Q000276:immunology / Q000469:parasitology; D015800:Protozoan Proteins / Q000502:physiology*
D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; D015800:Protozoan Proteins