Zoo-FISH with region-specific paints for mink chromosome 5q: delineation of inter- and intrachromosomal rearrangements in human, pig, and fox.
Comparison of evolutionarily conserved mammalian chromosomes homologous to human chromosome 17, performed with microdissected painting probes, revealed rearrangements inside these chromosomes in mink and pig and a disruption of this conserved region in the fox. Detection of a homologous region on an Iberian shrew chromosome showed the efficiency of microdissected painting probes for delineation of homologous chromosome regions in species belonging to orders that diverged at least 100 million years ago.
Rubtsov
N B
NB
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia. rubt@bionet.nsc.ru
Karamisheva
T V
TV
Astakhova
N M
NM
Liehr
T
T
Claussen
U
U
Zhdanova
N S
NS
D000818:Animals; D020223:Chromosome Painting / Q000379:methods*; D002875:Chromosomes / Q000235:genetics*; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics; D017124:Conserved Sequence / Q000235:genetics; D015342:DNA Probes / Q000235:genetics; D019143:Evolution, Molecular; D005589:Foxes / Q000235:genetics*; D006801:Humans; D008907:Mink / Q000235:genetics*; D011995:Recombination, Genetic / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D012788:Shrews / Q000235:genetics; D013552:Swine / Q000235:genetics*
D015342:DNA Probes