Successful treatment of enterovirus infection with the use of pleconaril in 2 infants with severe combined immunodeficiency.
Two patients with severe combined immunodeficiency and enterovirus infections were successfully treated with pleconaril. There were no adverse affects.
Nowak-Wegrzyn
A
A
Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287-3923, USA.
Phipatanakul
W
W
Winkelstein
J A
JA
Forman
M S
MS
Lederman
H M
HM
D000998:Antiviral Agents / Q000627:therapeutic use*; D004769:Enterovirus Infections / Q000150:complications / Q000188:drug therapy*; D005243:Feces / Q000821:virology; D005260:Female; D006801:Humans; D007223:Infant; D010069:Oxadiazoles / Q000627:therapeutic use*; D010080:Oxazoles; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000032:analysis; D016511:Severe Combined Immunodeficiency / Q000150:complications / Q000188:drug therapy*
D000998:Antiviral Agents; D010069:Oxadiazoles; D010080:Oxazoles; D012367:RNA, Viral; C115201:pleconaril