title: Restoration of propulsive peristalsis of the esophagus in achalasia.
abstract: The set consisting of 3 patients with esophageal achalasia diagnosed by manometry, pseudoachalasia excluded by esophagoscopy and endosonography, was treated with combined conservative procedure. Botulinum toxin 250u (Dysport) was applied to the area of lower esophageal sphincter and after 7 days balloon dilatation was carried out. Treatment efficacy was evaluated by the data obtained about the subjective condition, manometrically and endoscopically. The spine condition was evaluated in all patients before treatment and functional blockades were released by manual medicine and even by acupuncture. We succeeded in restoring propulsive peristalsis of the esophagus in all of them. It is objectively proven in the longest duration of 44 months in the case of a patient treated with a balloon dilatation.
authors: Department of Internal Medicine and Gastroenterology, Masaryk University Hospital, Brno, Czech Republic.
authors: A
authors: A
authors: Hep
authors: J
authors: J
authors: Dolina
authors: P
authors: P
authors: Dite
authors: Z
authors: Z
authors: Plottová
authors: V
authors: V
authors: Válek
authors: Z
authors: Z
authors: Kala
authors: J
authors: J
authors: Prásek
mesh_terms: D001905:Botulinum Toxins / Q000008:administration & dosage*; D002404:Catheterization; D003131:Combined Modality Therapy; D004931:Esophageal Achalasia / Q000628:therapy*; D004947:Esophagus / Q000502:physiology*; D006801:Humans; D008365:Manometry; D010528:Peristalsis; D016896:Treatment Outcome
chemical_list: D001905:Botulinum Toxins