title: IQ scores of treatment-resistant schizophrenia patients before and after the onset of the illness.
abstract: In this study we examined the correlations of actual pre-morbid IQ scores (obtained from routine educational assessments) and estimated current IQ scores in 27 treatment-resistant schizophrenia patients. Pre-morbid (mean = 93) and current (mean = 83) IQ scores were significantly correlated (r = 0.807, P < 0.0001), while duration of illness (10-40 years) was unrelated to the magnitude of IQ score decline (r = -0.103, P = 0.575). These data suggest that pre-morbid IQ test scores are highly predictive of post-morbid scores.
authors: Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA. Bsheitman@css.unc.edu
authors: B B
authors: BB
authors: Sheitman
authors: M G
authors: MG
authors: Murray
authors: J A
authors: JA
authors: Snyder
authors: S
authors: S
authors: Silva
authors: R
authors: R
authors: Goldman
authors: M
authors: M
authors: Chakos
authors: J
authors: J
authors: Volavka
authors: J A
authors: JA
authors: Lieberman
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D004311:Double-Blind Method; D004351:Drug Resistance; D005260:Female; D006801:Humans; D007360:Intelligence; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy*; D014888:Wechsler Scales
chemical_list: D014150:Antipsychotic Agents