Novel cytotoxic, polyprenylated heptacyclic xanthonoids from Indonesian Garcinia gaudichaudii (Guttiferae).
[reaction: see text] The structures of novel gaudichaudiic acids F-I (1-4), isolated from the bark of Indonesian Garcinia gaudichaudii, have been elucidated by detailed spectral analysis. Gaudichaudiic acid I (4) is probably derived from 1 as a result of allylic oxidation at C-24 and C-21, followed by aromatization.
Xu
Y J
YJ
Department of Chemistry, National University of Singapore, Kent Ridge, Singapore 119260.
Yip
S C
SC
Kosela
S
S
Fitri
E
E
Hana
M
M
Goh
S H
SH
Sim
K Y
KY
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification; D001952:Bridged-Ring Compounds / Q000737:chemistry* / Q000302:isolation & purification; D007214:Indonesia; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D019441:Plant Epidermis / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014966:Xanthenes / Q000138:chemical synthesis* / Q000302:isolation & purification
D000972:Antineoplastic Agents, Phytogenic; D001952:Bridged-Ring Compounds; D014966:Xanthenes