Hormones in male sexual development.
Classical embryology has provided a clear view of the timing and hormonal cues that govern sexual differentiation. Molecular biology has added important details to this picture. The cloning of SRY, MIS, and INSL3 provide insight into the molecular signals that provide important cues at the cellular level. Continued understanding of these pathways may provide the necessary information to one day reverse defects of sexual differentiation.
Nef
S
S
Center for Developmental Biology, University of Texas, Southwestern Medical Center, Dallas, Texas 75235-9133, USA.
Parada
L F
LF
D000818:Animals; D054304:Anti-Mullerian Hormone; D004967:Estrogens / Q000502:physiology; D005298:Fertility / Q000235:genetics; D005837:Genitalia, Male / Q000196:embryology / Q000254:growth & development*; D006023:Glycoproteins; D006131:Growth Inhibitors / Q000235:genetics / Q000378:metabolism; D006728:Hormones / Q000502:physiology*; D006801:Humans; D007328:Insulin; D008297:Male; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D012733:Sex Differentiation / Q000502:physiology*; D013735:Testicular Hormones / Q000235:genetics / Q000378:metabolism
D004967:Estrogens; D006023:Glycoproteins; D006131:Growth Inhibitors; D006728:Hormones; D007328:Insulin; C084797:Leydig insulin-like protein; D011506:Proteins; D013735:Testicular Hormones; D054304:Anti-Mullerian Hormone