Conceptual issues in trichotillomania, a prototypical impulse control disorder.
Impulse control disorders (ICDs) are characterized by irresistible urges to perform acts that result in a reduction of tension and possibly gratification, but also have negative consequences. Trichotillomania, an ICD, is characterized by a recurrent failure to resist impulses to pull out one's hair, resulting in noticeable hair loss. Limited information is available about structural and neurochemical differences in individuals with trichotillomania. Cognitive behavioral techniques are promising treatments for trichotillomania. Pharmacologic treatments have focussed on clomipramine and venlafaxine as potentially effective for the short term control of symptoms in trichotillomania. Selective serotonin reuptake inhibitors, though promising in open trials, seem to be largely ineffective in reducing hair pulling in controlled studies. Durability of pharmacologic benefit for the symptoms of trichotillomania, both in a small trial and in clinical experience, appears to be poor.
Ninan
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Emory University School of Medicine, 1841 Clifton Road, Room 401, Atlanta, GA 30329, USA. philninan@learnlink.emory.edu
D000328:Adult; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000175:diagnosis* / Q000378:metabolism / Q000523:psychology; D005260:Female; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010913:Pituitary-Adrenal System / Q000378:metabolism; D011569:Psychiatric Status Rating Scales; D014256:Trichotillomania / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism