Plant stem cells: the only constant thing is change.
Recent studies in Arabidopsis have uncovered a negative feedback loop that couples the antagonistic functions of the WUSCHEL and CLAVATA loci to control stem cell fate in the shoot apical meristem. Abundance of the CLAVATA3 protein limits signaling through this pathway.
Doerner
P
P
Institute of Cell and Molecular Biology, University of Edinburgh, Swann Building, EH9 3JR, Scotland, Edinburgh, UK. Peter.Doerner@ed.ac.uk
D017360:Arabidopsis; D029681:Arabidopsis Proteins; D002454:Cell Differentiation; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism* / Q000502:physiology; D018517:Plant Roots / Q000254:growth & development / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*; D013234:Stem Cells / Q000166:cytology*
D029681:Arabidopsis Proteins; C401621:CLV2 protein, Arabidopsis; D018398:Homeodomain Proteins; D008565:Membrane Proteins; D010940:Plant Proteins; C097496:STM protein, Arabidopsis; C116421:WUSCHEL protein, Arabidopsis