title: Non-FcR-binding, humanized anti-CD3 antibody Hu291 induces apoptosis of human T cells more effectively than OKT3 and is immunosuppressive in vivo.
authors: Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
authors: P A
authors: PA
authors: Carpenter
authors: J Y
authors: JY
authors: Tso
authors: O W
authors: OW
authors: Press
authors: X
authors: X
authors: Yu
authors: C
authors: C
authors: Anasetti
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects / Q000276:immunology*; D006086:Graft vs Host Disease / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D017710:Lymphocyte Transfusion; D051379:Mice; D016688:Mice, Inbred NOD; D016513:Mice, SCID; D016853:Muromonab-CD3 / Q000494:pharmacology*; D017260:Receptor-CD3 Complex, Antigen, T-Cell / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects* / Q000276:immunology; D014183:Transplantation, Heterologous / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D007166:Immunosuppressive Agents; D016853:Muromonab-CD3; D017260:Receptor-CD3 Complex, Antigen, T-Cell