Acute reversible cardiomyopathy and thromboembolism after cisplatin and 5-fluorouracil chemotherapy--a case report.
Acute development of cardiomyopathy and occlusive thromboembolic events following cisplatin and 5-fluorouracil (5-FU) is rare but frequently lethal. The authors report the successful management of such an event in a 52-year-old man with squamous cell carcinoma of the soft palate. The possible pathophysiological mechanisms are discussed.
Cheriparambil
K M
KM
Division of Cardiology, The New York Methodist Hospital, Brooklyn, New York 11215, USA.
Vasireddy
H
H
Kuruvilla
A
A
Gambarin
B
B
Makan
M
M
Saul
B I
BI
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy; D009202:Cardiomyopathies / Q000139:chemically induced*; D002945:Cisplatin / Q000009:adverse effects*; D005472:Fluorouracil / Q000009:adverse effects*; D006331:Heart Diseases / Q000139:chemically induced*; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D010157:Palatal Neoplasms / Q000188:drug therapy; D013923:Thromboembolism / Q000139:chemically induced*; D014463:Ultrasonography
D002945:Cisplatin; D005472:Fluorouracil