title: Trapping intermediates in the crystal: ligand binding to myoglobin.
abstract: Crystal structures of the reactive short-lived species that occur in chemical or binding reactions can be determined using X-ray crystallography via time-resolved or kinetic trapping approaches. Recently, various kinetic trapping methods have been used to determine the structure of intermediates in ligand binding to myoglobin.
authors: Max Planck Institute for Molecular Physiology, Department for Physical Biochemistry, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany. ilme.schlichting@mpi-dortmund.mpg.de
authors: I
authors: I
authors: Schlichting
authors: K
authors: K
authors: Chu
mesh_terms: D018360:Crystallography, X-Ray; D008024:Ligands; D008958:Models, Molecular; D009211:Myoglobin / Q000737:chemistry / Q000378:metabolism*; D011485:Protein Binding; D011487:Protein Conformation
chemical_list: D008024:Ligands; D009211:Myoglobin