Myelodysplastic syndrome and a nonrandom chromosomal abnormality t(1;19): an indolent pathologic entity.
The chromosomal abnormality t(1;19) is an infrequent finding in adult hematopoietic malignancies. This is only the second report of t(1;19) in association with myelodysplastic syndrome in which there was an apparent excellent response to oral cyclosporin A and a very indolent clinical course.
Forrest
D L
DL
Division of Hematology and Department of Pathology, Queen Elizabeth II Health Sciences Centre, Izaak Walton Grace Health Science Centre, Dalhousie University, Halifax, Nova Scotia, Canada. dforrest@is.dal.ca
Couban
S
S
Nevill
T J
TJ
Lee
C Y
CY
Welch
P J
PJ
D000293:Adolescent; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics*; D002888:Chromosomes, Human, Pair 19 / Q000235:genetics*; D005260:Female; D006801:Humans; D007621:Karyotyping; D009190:Myelodysplastic Syndromes / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic