Self-organizing neural networks for screening and development of novel artificial sweetener candidates.
The use of Kohonen feature maps for the visualization of various aspects of molecular similarity is briefly reviewed and illustrated. It is shown that a specific feature of self-organizing maps (SOM) makes them of special interest for the screening of compounds. In particular, these methods were used to design candidates for new sweeteners, which were then synthesized.
Polanski
J
J
Institute of Chemistry, University of Silesia, Szkolna 9, PL-40006 Katowice, Poland. polanski@us.edu.pl
Jarzembek
K
K
Gasteiger
J
J
D016208:Databases, Factual; D008956:Models, Chemical; D016571:Neural Networks, Computer; D013549:Sweetening Agents / Q000138:chemical synthesis* / Q000494:pharmacology
D013549:Sweetening Agents