The impact of resistance on the management of urinary tract infections.
Urinary tract infections requiring treatment are extremely common. It is estimated that between 20 and 50% of adult women will have had at least one symptomatic urinary tract infection. When considering the optimal therapy of any infection, patient factors, organism factors, drug factors (e.g. pharmacokinetics), side-effects and cost as well as antimicrobial resistance all need to be considered. This paper deals with the impact of increasing antibiotic resistance on the management of urinary tract infections.
Sefton
A M
AM
Department of Medical Microbiology, St Bartholomew's and the Royal London School of Medicine and Dentistry, Turner St, London E1 2AD, UK. a.sefton@mds.qmw.ac.uk
D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000191:economics / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001437:Bacteriuria / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D005260:Female; D006801:Humans; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control
D000900:Anti-Bacterial Agents