Characterization of caldarchaetidylglycerol analogs, dialkyl-type and trialkyl-type, from Thermoplasma acidophilum.
The structures of three kinds of phospholipids (PL-X, PL-Y, and PL-T) isolated from Thermoplasma acidophilum have been characterized. The core lipid of PL-Y was caldarchaeol, and that of PL-X was archaeol. The composition of the hydrocarbon chains of the PL-T core lipid was C20 phytane and C40 isoprenoid in a molar ratio of 2 to 1. The major molecular species of the C40 isoprenoid was acyclic without the cyclopentane ring. These three kinds of intact phospholipids commonly had glycerophosphate residues as polar head groups. The structure of PL-T was characterized as trialkyl-type caldarchaetidylglycerol, PL-Y as caldarchaetidylglycerol, and PL-X as archaetidylglycerol.
Uda
I
I
Division of Chemistry, Center for Natural Science, Kitasato University, Kanagawa, Japan. uda@clas.kitasato-u.ac.jp
Sugai
A
A
Itoh
Y H
YH
Itoh
T
T
D002845:Chromatography; D002855:Chromatography, Thin Layer; D005995:Glyceryl Ethers / Q000737:chemistry / Q000302:isolation & purification; D008956:Models, Chemical; D010743:Phospholipids / Q000737:chemistry* / Q000302:isolation & purification*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013822:Thermoplasma / Q000737:chemistry*
D005995:Glyceryl Ethers; D010743:Phospholipids; C094417:archaeol lipid; C094418:caldarchaeol