title: Predicting arm recovery following stroke: value  of site of lesion.
abstract: OBJECTIVE
  The aims of this study were to assess whether the site of lesion is predictive of upper limb recovery after stroke and to determine whether this information adds to the predictive ability of the clinical examination.
  
  
  METHODS
  Forty-five patients were examined at entry to the study and at 2 and 12 months after stroke. The Brunnström-Fugl-Meyer test was used as outcome measurement. Predictor variables included clinical parameters and classifications of lesion site (obtained by CT/MRI).
  
  
  RESULTS
  Correlation analysis revealed small to moderate relationships between lesions of subcortical structures and arm outcome at 2 months. In multiple regression analysis, the best model for predicting recovery at 2 months was found to be a combination of the clinical parameters with a purely subcortical lesion. Motor recovery at 12 months was best predicted by the clinical tests alone. The results further indicated that patients with subcortical damage tended to take longer to recover.
  
  
  CONCLUSIONS
  Clinical assessment is most useful for determination of the prognosis of upper limb recovery after stroke. Neuroanatomical parameters measured by CT or MRI can only act as an adjunct.
authors: Department of Rehabilitation Sciences, Faculty of Physical Education and Physiotherapy, University of Leuven, Belgium. Hilde.Feys@flok.kuleuven.ac.be
authors: H
authors: H
authors: Feys
authors: J
authors: J
authors: Hetebrij
authors: G
authors: G
authors: Wilms
authors: R
authors: R
authors: Dom
authors: W
authors: W
authors: De Weerdt
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001132:Arm; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019957:Motor Skills Disorders / Q000209:etiology* / Q000534:rehabilitation; D010808:Physical Examination; D011237:Predictive Value of Tests; D020521:Stroke / Q000150:complications; D000071939:Stroke Rehabilitation