Oligomers of enantiopure bicyclic gamma/delta-amino acids (BTAa). 1. Synthesis and conformational analysis of 3-aza-6,8-dioxabicyclo
A series of dimeric through pentameric oligomers of a bicyclic gamma/delta-amino acid (BTG) were synthesized using peptide coupling methods in solution with PyBroP or HATU. The analysis of (1)H NMR and CD spectra suggests that these oligomers could have a partially ordered structure in alcohol solutions.
Machetti
F
Dipartimento di Chimica Organica "U. Schiff" and Centro di Studio sulla Chimica e la Struttura dei Composti Eterociclici e loro Applicazioni, C.N.R., Universita di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy.
Ferrali
A
Menchi
G
Occhiato
EG
Guarna
A