The consolidation and compressibility properties of some novel directly compressible filler-binders.
The aim of this study was to investigate the consolidation and compressibility properties and also the dilution potentials of some novel directly compressible filler-binders. For this purpose, Ludipress and Cellastose 80 (one-body compounds), Tablettose 70 and Tablettose 80 (alpha-mono agglomerated lactose) were selected. They were diluted at predetermined percentages with Spherolac 100 which is a coarse sieved hydrous crystalline lactose. The consolidation and compressibility properties of the prepared powder mixtures were determined. The experimental data were evaluated by using a computer programme (Basic 80).
Gönül
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N
Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Tandoğan Sq., 06100 Ankara, Turkey.
Oğan-Hasçiçek
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C
Baykara
T
T
D000465:Algorithms; D002626:Chemistry, Pharmaceutical; D004339:Drug Compounding; D005079:Excipients; D011208:Powders; D013607:Tablets
D005079:Excipients; D011208:Powders; D013607:Tablets