title: Darier's disease: a new paradigm for genetic studies in psychiatric disorders.
abstract: BACKGROUND
  One strategy for identifying susceptibility genes for common disorders is to investigate Mendelian diseases, cosegregating with these common disease phenotypes.
  
  
  METHODS
  A family with seven members is described, in which three members present Darier's disease and depression. This apparent cosegregation, if true, would support the hypothesis that in some pedigrees, a gene for mood disorder may be located on chromosome 12.
authors: Institute of Psychiatry, School of Medicine, Universidade de São Paulo, São Paulo, Brazil.
authors: Q
authors: Q
authors: Cordeiro
authors: D M
authors: DM
authors: Werebe
authors: H
authors: H
authors: Vallada
mesh_terms: D000328:Adult; D020090:Chromosome Segregation / Q000235:genetics; D002881:Chromosomes, Human, Pair 12 / Q000235:genetics; D007644:Darier Disease / Q000150:complications / Q000235:genetics* / Q000523:psychology; D003863:Depression / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D019964:Mood Disorders / Q000235:genetics; D010375:Pedigree