title: Synthesis and lateral root-inducing activity of novel N-substituted-2-piperidones with a 1,4-benzodioxan ring.
abstract: Novel N-substituted-2-piperidones with a 1,4-benzodioxan ring were prepared and evaluated for their activity to induce lateral roots in lettuce seedlings. Compounds were obtained by aldol condensation of the lithium enolate of N-substituted-2-piperidones with 1,4-benzodioxan-6-carbaldehyde. Of the series compounds tested, N-cinnamyl-3-[1-(1,4-benzodioxan-6-yl)-1-hydroxymethyl]-2-piperidone (2e) had the highest activity. In seedlings treated with 10 ppm of 2e, all of the primary roots formed lateral roots. Only erythro-2e showed lateral root-inducing activity, while threo-2e was inactive.
authors: Division of Bioresource and Bioenvironmental Sciences, Graduate School, Kyushu University, Fukuoka, Japan.
authors: H
authors: H
authors: Tsukada
authors: N
authors: N
authors: Yamada
authors: E
authors: E
authors: Taniguchi
authors: E
authors: E
authors: Kuwano
mesh_terms: D004146:Dioxanes / Q000737:chemistry*; D018545:Lactuca; D010881:Piperidones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots / Q000254:growth & development*
chemical_list: D004146:Dioxanes; D010881:Piperidones; C025223:1,4-dioxane