Epilepsy and epileptiform EEG: association with autism and language disorders.
The relationship between epilepsy, language, behavior, and cognition is not well understood. Developmental and acquired disabilities such as autistic spectrum disorders, Landau-Kleffner Syndrome, electrical status epilepticus in sleep, and developmental dysphasias have been associated with epileptiform abnormalities. These disorders share many common features and raise important questions regarding this intricate relationship. This article reviews these disorders and discusses the proposed interaction between epileptiform abnormalities and cognitive dysfunction. Diagnostic and treatment issues will also be reviewed.
Ballaban-Gil
K
K
Departments of Neurology and Pediatrics and the Montefiore/AECOM Epilepsy Management Unit, Albert Einstein College of Medicine, Bronx, New York, USA.
Tuchman
R
R
D001321:Autistic Disorder / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D001921:Brain / Q000002:abnormalities / Q000473:pathology / Q000503:physiopathology; D002648:Child; D004569:Electroencephalography / Q000523:psychology / Q000706:statistics & numerical data; D004827:Epilepsy / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D018887:Landau-Kleffner Syndrome / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D007806:Language Disorders / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D012043:Regression, Psychology; D012890:Sleep / Q000502:physiology; D013226:Status Epilepticus / Q000150:complications / Q000473:pathology / Q000503:physiopathology