title: Effect of multifaceted intervention promoting early switch from intravenous to oral acetaminophen for postoperative pain: controlled, prospective, before and after study.
abstract: OBJECTIVE
  Need to improve the efficiency of postoperative pain management by early switching from intravenous to oral acetaminophen.
  
  
  METHODS
  Implementation of local guidelines aimed at improving nurses' and doctors' behaviour. A controlled, prospective, before and after study evaluated its impact on appropriateness and costs.
  
  
  METHODS
  Orthopaedic surgery department (intervention) and all other surgical departments (control) of a university hospital. Five anaesthetists and 30 nurses of orthopaedic department participated in study.
  
  
  METHODS
  Reducing number of acetaminophen injections per patient, reducing consumption of acetaminophen injections; cost savings over a one year period.
  
  
  METHODS
  Multifaceted intervention included a local consensus process, short educational presentation, poster displayed in all nurses' offices, and feedback of practices six months after implementation of guidelines.
  
  
  RESULTS
  Mean number of acetaminophen injections per patient decreased from 6.81 before intervention to 2.36 six months after. Monthly consumption of acetaminophen injections per 100 patients decreased by 320.9 (95% confidence interval 192.4 to 449.4) in intervention department and remained unchanged in control departments. Annual cost reduction was projected to be pound 15,100.
  
  
  CONCLUSIONS
  Simple and locally implemented guidelines can improve practices and cut costs. Educational interventions can improve professionals' behaviour when they are based on actual working practices, use interactive techniques such as discussion groups, and are associated with other effective implementation strategies.
authors: Department of Pharmacy, Hôpital Cochin, 27, rue du Faubourg Saint-Jacques, 75006 Paris, France.
authors: C
authors: C
authors: Ripouteau
authors: O
authors: O
authors: Conort
authors: J P
authors: JP
authors: Lamas
authors: G R
authors: GR
authors: Auleley
authors: G
authors: G
authors: Hazebroucq
authors: P
authors: P
authors: Durieux
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage*; D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage*; D003657:Decision Making; D006801:Humans; D007275:Injections, Intravenous; D008875:Middle Aged; D019637:Orthopedic Procedures; D010149:Postoperative Pain / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen