title: The intrinsic function of a motor system--from ion channels to networks and behavior.
abstract: The forebrain, brainstem and spinal cord contribution to the control of locomotion is reviewed in this article. The lamprey is used as an experimental model since it allows a detailed cellular analysis of the neuronal network underlying locomotion. The focus is on cellular mechanisms that are important for the pattern generation, as well as different types of pre- and postsynaptic modulation. This experimental model is bridging the gap between the molecular and cellular level to the network and behavioral level.
authors: Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet, SE-171 77, Stockholm, Sweden. sten.grillner@neuro.ki.se
authors: S
authors: S
authors: Grillner
authors: L
authors: L
authors: Cangiano
authors: G
authors: G
authors: Hu
authors: R
authors: R
authors: Thompson
authors: R
authors: R
authors: Hill
authors: P
authors: P
authors: Wallén
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D001933:Brain Stem / Q000502:physiology; D003198:Computer Simulation; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology; D006801:Humans; D007473:Ion Channels / Q000378:metabolism*; D007798:Lampreys; D008124:Locomotion / Q000502:physiology*; D008959:Models, Neurological; D009043:Motor Activity / Q000502:physiology*; D009415:Nerve Net / Q000378:metabolism*; D018377:Neurotransmitter Agents / Q000378:metabolism; D016548:Prosencephalon / Q000502:physiology; D013116:Spinal Cord / Q000502:physiology
chemical_list: D007473:Ion Channels; D018377:Neurotransmitter Agents