title: Histopathology of the inferior turbinate with compensatory hypertrophy in patients with deviated nasal septum.
abstract: OBJECTIVE
  To measure the dimensions, composition, and possible structural and/or histopathological changes of the compensatory hypertrophic inferior turbinate in patients with deviated nasal septum.
  
  
  METHODS
  A prospective, nonrandomized, and morphometric study.
  
  
  METHODS
  Nineteen patients with deviated nasal septum and compensatory hypertrophy of the inferior turbinate in the contralateral nasal cavity underwent surgery for correction of nasal obstruction. Patients' specimens were compared with those of a control group consisting of 10 inferior turbinates removed at autopsy. Quantitative measurements of the inferior turbinate histological sections were carried out and included the width of the layers and morphometric calculations of the relative proportions of the soft tissue constituents. Also, qualitative study was performed to detect pathological changes.
  
  
  RESULTS
  Of all layers, the inferior turbinate bone underwent a twofold increase in thickness and manifested the most significant expansion (P < or =.001), whereas the contribution of the mucosal layers to the inferior turbinate hypertrophy was modest. The morphometric analysis revealed a larger proportion of venous sinusoids in hypertrophic turbinates, but the difference was small and statistically insignificant. Qualitative assessment disclosed normal mucosal architecture in all inferior turbinates with compensatory hypertrophy. Eleven remained intact, while eight disclosed mild to moderate pathological changes.
  
  
  CONCLUSIONS
  The data gathered in the present study are of importance to the decision-making process regarding turbinate surgery. The significant bone expansion and the relative minor role played by the mucosal hypertrophy would support the decision to excise the inferior turbinate bone at the time of septoplasty.
authors: Department of Otolaryngology--Head and Neck Surgery, Meir General Hospital, Kfar Saba, Israel.
authors: G
authors: G
authors: Berger
authors: I
authors: I
authors: Hammel
authors: R
authors: R
authors: Berger
authors: S
authors: S
authors: Avraham
authors: D
authors: D
authors: Ophir
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D006984:Hypertrophy; D008875:Middle Aged; D009297:Nasal Mucosa / Q000473:pathology*; D009300:Nasal Septum / Q000473:pathology*; D009667:Nose Deformities, Acquired / Q000473:pathology*; D014420:Turbinates / Q000473:pathology*