Synthesis of a triphenylphosphine reagent on non-cross-linked polystyrene support: application to the Staudinger/Aza-wittig reaction
A new triphenylphosphine reagent linked to a linear polystyrene was synthesized. The reactivity of this phosphine-bound polymer is superior to that of the phosphine bound to cross-linked polystyrene. The polymer reacted very rapidly with azides to generate iminophosphoranes which could then react with aldehydes to generate imines in good yields and high purities.
Charette
AB
Departement de chimie, Universite de Montreal, Quebec, Station Downtown, Canada H3C 3J7.
Boezio
AA
Janes
MK