Cellular and molecular aspects of iron and immune function.
Fe plays a critical role in the immune system and defence against infection. However, many aspects of the way in which Fe influences these processes at the molecular and cellular level are unclear. The present review summarizes the role of Fe in lymphocyte activation and proliferation, and discusses how Fe is handled by macrophages.
Brock
J H
JH
Department of Immunology, Western Infirmary, Glasgow G11 6NT, UK. j.h.brock@clinmed.gla.ac.uk
Mulero
V
V
D006801:Humans; D007501:Iron / Q000276:immunology* / Q000378:metabolism; D008213:Lymphocyte Activation / Q000502:physiology; D008214:Lymphocytes / Q000502:physiology*; D008264:Macrophages / Q000502:physiology*
D007501:Iron