[HPLC-separation of racemic cyclohexane-1,2-diamine platinum(II)  dimyristates on chiral stationary phases]  .
In this paper, the stereochemical resolution of racemic cyclohexane-1,2-diamine platinum(II) dimyristates on chiral stationary phases (CSP) is described. These CSP are Pirkle phases chiral column (Sumichiral OA-2500, 3100, 3200, 3300, 4000, 4100). Among them, the Sumichiral OA-2500 column gave the best results. The effects of the temperature and mobile phase composition as well as the hydrophobicity of the analytes on the chromatographic separation are described.
Okamoto
M
M
Environmental Health Science Laboratory, Sumitomo Chemical Co., Ltd., Osaka, Japan.
Takahashi
K
K
Takimoto
Y
Y
Kishimoto
H
H
D002851:Chromatography, High Pressure Liquid; D009944:Organoplatinum Compounds / Q000737:chemistry* / Q000302:isolation & purification; D012996:Solutions; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism; D013696:Temperature
D009944:Organoplatinum Compounds; D012996:Solutions; C406530:miriplatin