Effect of dietary flaxseed, flax oil and n-3 fatty acid supplement on hepatic and plasma characteristics relevant to fatty liver haemorrhagic syndrome in laying hens.
1. Two experiments were carried out to investigate the effect of dietary flaxseed, flax oil and n-3 fatty acid supplementation (Dry n-3) on hepatic fat content, plasma triglycerides, hepatic haemorrhage score, egg production, food intake and body weight in an inbred line of Single Comb White Leghorns (UCD-003) predisposed to fatty liver haemorrhagic syndrome (FLHS) and normal SCWL hens. 2. Feeding diets containing 100 g/kg ground flaxseed, 40 g/kg flax oil, or 100 g/kg Dry n-3 reduced body weight and significantly reduced hepatic fat content compared to feeding the control diet with animal and vegetable oil as a fat source. 3. Hepatic malondialdehyde, an indicator of lipid peroxidation within the liver, was not significantly affected by dietary treatment. 4. Normal SCWL hens tended to have higher egg production, greater body weight, greater food intake and higher blood triglyceride concentrations than UCD-003 hens, although the strain effects were not significant. Liver weight as a percent of body weight was significantly lower in normal SCWL hens. Treatments by strain interactions were not found. 5. The result suggested that dietary flaxseed, flax oil and Dry n-3 decrease hepatic fat content and reduce body weight, 2 of the predisposing factors believed to contribute to FLHS onset. However, haemorrhages were still apparent in both strains regardless of treatment, indicating that other unknown underlying mechanisms may also be responsible for FLHS.
Schuman
B E
BE
Department of Animal and Poultry Science, University of Guelph, Ontario, Canada.
Squires
E J
EJ
Leeson
S
S
D000821:Animal Feed; D000818:Animals; D002645:Chickens; D019587:Dietary Supplements; D004435:Eating; D004531:Eggs; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage / Q000378:metabolism*; D005234:Fatty Liver / Q000473:pathology / Q000662:veterinary*; D005260:Female; D019597:Flax / Q000378:metabolism*; D008043:Linseed Oil / Q000008:administration & dosage / Q000378:metabolism*; D008099:Liver / Q000737:chemistry; D008315:Malondialdehyde / Q000032:analysis; D010058:Oviposition; D011201:Poultry Diseases / Q000473:pathology*; D011897:Random Allocation; D014280:Triglycerides / Q000097:blood
D015525:Fatty Acids, Omega-3; D014280:Triglycerides; D008315:Malondialdehyde; D008043:Linseed Oil