The emerging role of HDL cholesterol. Is it time to focus more energy on raising high-density lipoprotein levels?
Low HDL cholesterol levels have been found to be a risk factor for CAD. To date, the focus of treating hyperlipidemia has been on lowering LDL cholesterol levels. Now, as more and more compelling data are reported, it is time to begin focusing more energy on how to raise HDL cholesterol levels. If exercise, smoking cessation, and moderate alcohol consumption fail to achieve HDL cholesterol goals, niacin, fibric acid derivatives, or statin drugs may prove helpful in patients at high risk of CAD.
Safeer
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Division of Family Practice, George Washington University School of Medicine and Health Sciences, Rockville, MD, USA.
Cornell
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D000428:Alcohol Drinking; D001835:Body Weight; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood / Q000172:deficiency*; D003327:Coronary Disease / Q000097:blood / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control*; D004041:Dietary Fats / Q000008:administration & dosage / Q000009:adverse effects; D015914:Estrogen Replacement Therapy; D015444:Exercise; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D015994:Incidence; D008019:Life Style; D009525:Niacin / Q000627:therapeutic use; D009765:Obesity / Q000150:complications; D010809:Physical Fitness; D011322:Primary Prevention / Q000379:methods*; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
D008076:Cholesterol, HDL; D004041:Dietary Fats; D000960:Hypolipidemic Agents; D009525:Niacin; D002784:Cholesterol