Definition, interpretation and calculation of cost-effectiveness acceptability curves.
This paper discusses the definition, interpretation and computation of cost-effectiveness (CE) acceptability curves. A formal definition of the CE acceptability curve based on the net benefit approach is provided. The curve can be computed using parametric or non-parametric techniques and for both computational approaches we establish a formal relation between the CE acceptability curve and statistical inference based on confidence intervals and P values in CE analysis.
Löthgren
M
M
AstraZeneca R&D Södertälje, Health Economics and Outcomes Research, Sweden.
Zethraeus
N
N
D003362:Cost-Benefit Analysis / Q000706:statistics & numerical data*; D003627:Data Interpretation, Statistical; D005249:Fees and Charges; D006302:Health Services Research / Q000191:economics / Q000379:methods / Q000706:statistics & numerical data*; D006801:Humans; D017059:Models, Econometric; D011336:Probability; D018709:Statistics, Nonparametric