Demystifying two common genetic predispositions to venous thrombosis.
Two recently discovered genetic abnormalities substantially increase the risk of venous thromboembolism. Yet we do not advocate screening for these abnormalities except in cases in which the information gained would affect the course of action.
Deitcher
S R
SR
Department of Vascular Medicine, Cleveland Clinic Foundation, OH 44195, USA. deitchs@ccf.org
Caiola
E
E
Jaffer
A
A
D020016:Activated Protein C Resistance / Q000235:genetics; D005165:Factor V / Q000235:genetics; D020022:Genetic Predisposition to Disease; D006801:Humans; D017354:Point Mutation; D011516:Prothrombin / Q000235:genetics; D020246:Venous Thrombosis / Q000235:genetics*
C095381:factor V Leiden; D005165:Factor V; D011516:Prothrombin