Preoperative dobutamine stress echocardiography versus cardiac arteriography for risk assessment prior to renal transplantation.
Because coronary artery disease is the leading cause of death in patients with end-stage renal disease, we prospectively studied the prognostic value of dobutamine stress echocardiography (DSE) compared to coronary angiography (CA) as an evaluative tool. Thirty-three patients at high risk for coronary artery disease were selected from a cohort of 133 renal transplant candidates and underwent both DSE and CA. In this study, the value of DSE was found to exist in its strong negative predictive value (92%). A negative DSE coupled with a negative clinical cardiac evaluation was found to practicably exclude the necessity for CA. DSE can thus serve as a non-invasive, low cost screening test.
West
J C
JC
Department of Surgery, Geisinger Medical Center, Danville, PA 17822, USA.
Napoliello
D A
DA
Costello
J M
JM
Nassef
L A
LA
Butcher
R J
RJ
Hartle
J E
JE
McConnell
T R
TR
Finley
J W
JW
Kelley
S E
SE
Chao
S
S
Latsha
R
R
D000318:Adrenergic beta-Agonists; D017023:Coronary Angiography; D003327:Coronary Disease / Q000453:epidemiology*; D004280:Dobutamine; D004452:Echocardiography / Q000187:drug effects; D006801:Humans; D016030:Kidney Transplantation; D008875:Middle Aged; D011183:Postoperative Complications; D011237:Predictive Value of Tests; D011446:Prospective Studies; D018570:Risk Assessment; D012307:Risk Factors
D000318:Adrenergic beta-Agonists; D004280:Dobutamine