Postprandial lipemia and coronary risk.
A number of cross-sectional studies have demonstrated that the magnitude of postprandial lipemia or single postprandial triglyceride values predict asymptomatic and symptomatic atherosclerosis, independent of risk factors measured in the fasting state. Postprandial lipemia reflects an integrated measure of an individual's triglyceride metabolic capacity. Numerous genetic and environmental factors that are known or suspected to affect triglyceride transport contribute to the magnitude of postprandial lipemia. In this article, mechanisms linking postprandial lipemia with the development and progression of atherosclerosis are described, and determinants of the extent and duration of postprandial lipemia are discussed.
Patsch
W
W
Department of Laboratory Medicine, Landeskliniken Salzburg, Müllner Hauptstr. 48, A-5020 Salzburg, Austria. w.patsch@lkasbg.gv.at
Esterbauer
H
H
Föger
B
B
Patsch
J R
JR
D001161:Arteriosclerosis / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D019518:Postprandial Period / Q000502:physiology*; D012307:Risk Factors; D014280:Triglycerides / Q000502:physiology*
D014280:Triglycerides