Theophylline as a therapy for chronic lymphocytic leukemia: a case report and review of literature.
We herein, report that theophylline which can induce apoptosis in chronic lymphocytic leukemia (CLL) cells both in vitro and in vivo, also appears to be effective when used clinically to treat an advanced CLL patient.
Basu
S
S
Department of Medical Oncology, Chittaranjan National Cancer Institute, Calcutta, India. cncinst@giasc101.vsnl.net.in
Mitra Basu
R
R
D000368:Aged; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy*; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use*; D013806:Theophylline / Q000627:therapeutic use*
D010726:Phosphodiesterase Inhibitors; D013806:Theophylline