title: The relationship of the International Prostate Symptom Score and objective parameters for diagnosing bladder outlet obstruction. Part II: the potential usefulness of artificial neural networks.
abstract: OBJECTIVE
  The International Prostate Symptom Score (I-PSS) is used exclusively for evaluating patients with a prostate condition and following various treatment modalities. As previously demonstrated, there is poor or no correlation of bladder outlet obstruction diagnosed by pressure flow study with the symptoms projected by the I-PSS. Thus, we applied an artificial neural network model to assess patients with lower urinary tract symptoms.
  
  
  METHODS
  Data on 460 patients enrolled in part 1 of our study were entered into a multilayer feed forward, back propagation network.
  
  
  RESULTS
  In the training set of 305 patients the model predicted obstruction in 94% with 94% sensitivity and 68% specificity. In the test set of 155 patients it predicted obstruction in 87% with 87% sensitivity and 44% specificity.
  
  
  CONCLUSIONS
  The accuracy of the model for diagnosing obstruction based on the I-PSS is acceptable, considering that statistical models failed to demonstrate a correlation of symptoms with objective obstruction.
authors: Urology and Nephrology Center, Mansoura University, Mansoura and Biomedical Engineering Department, Faculty of Engineering, Cairo University, Cairo, Egypt.
authors: B S
authors: BS
authors: Wadie
authors: A M
authors: AM
authors: Badawi
authors: M A
authors: MA
authors: Ghoneim
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017143:Fuzzy Logic; D006801:Humans; D008297:Male; D008875:Middle Aged; D016571:Neural Networks, Computer; D011237:Predictive Value of Tests; D011470:Prostatic Hyperplasia / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D001748:Urinary Bladder Neck Obstruction / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology