Antioxidative activity of (-)-epigallocatechin-3-(3''-O-methyl)gallate isolated from fresh tea leaf and preliminary results on its biological activity.
Antioxidative activity of (-)-epigallocatechin-3-(3''-O-methyl)gallate (catechin e) was examined. Catechin e showed a strong antioxidative activity. A preliminary test using rat cancer cells suggests that catechin e also has a strong cytotoxic activity. Among tested catechins, only catechin e has strong activity for both.
Kawase
M
M
Faculty of Agriculture, Kagawa University, Takamatsu, Japan.
Wang
R
R
Shiomi
T
T
Saijo
R
R
Yagi
K
K
D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002392:Catechin / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D008114:Liver Neoplasms, Experimental / Q000473:pathology; D051381:Rats; D013662:Tea / Q000737:chemistry*; D014407:Tumor Cells, Cultured
D000975:Antioxidants; D013662:Tea; C420224:epigallocatechin-3-(3''-O-methyl)gallate; D002392:Catechin