[Association of Kaposi sarcoma--multiple myeloma. A new case].
BACKGROUND
Kaposi's disease is an angiogenic multifocal cancer process that has several forms, namely Mediterranean, African, HIV-associated, and secondary to a preexisting immunodepressive state (hematological disorder, corticosteroid therapy, immunodepressive treatment). Whatever its form, Kaposi's sarcoma is probably associated with a chronic viral human herpes type 8 infection (HHV8).


METHODS
This virus has been implicated in the pathogenesis of multiple myeloma (17 cases recorded to date). In the present study, a further case of Kaposi's sarcoma associated with multiple myeloma has been reported. However, Epstein-Barr virus, cytomegalovirus, hepatitis B and C, HIV and HHV8 serologies were negative. Radiotherapy on the lower limbs was initiated.


CONCLUSIONS
It is concluded that HHV8 does not appear to play a pathogenic role in cases of multiple myeloma, given the rarity of the association between Kaposi's sarcoma/multiple myeloma/HHV8.
Cohen
J D
JD
Service de rhumatologie, hôpital Lapeyronie, Montpellier, France.
Thomas
E
E
Garnier
N
N
Hellier
I
I
Durand
L
L
Guilhou
J J
JJ
Baldet
P
P
Blotman
F
F
D000368:Aged; D000369:Aged, 80 and over; D003587:Cytomegalovirus / Q000302:isolation & purification; D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy; D009367:Neoplasm Staging; D012514:Sarcoma, Kaposi / Q000150:complications* / Q000175:diagnosis / Q000532:radiotherapy