title: [First description of concomitant infection with tuberculosis and paratuberculosis in dairy sheep in Argentina].
abstract: The authors present the results of a comparative intradermal tuberculin test performed on dairy sheep to determine rates of reaction to bovine and avian purified protein derivative (PPD). Test reactions were interpreted by palpation and measurement with a calliper. Results were analysed by plotting the values obtained. Agar gel immunodiffusion tests, growth in culture and histopathological examinations were also performed to allow differential diagnosis between tuberculosis and paratuberculosis. In the first tuberculin test, performed on 288 sheep, 74 animals showed a positive reaction to avian PPD (25.69%), two animals showed a positive reaction to bovine PPD (0.69%), and one animal was positive with respect to both tuberculins (0.34%). In the second test, involving 247 sheep, 55 demonstrated a positive reaction to avian PPD (22.26%), whilst none reacted to bovine PPD. The presence of Mycobacterium avium subsp. paratuberculosis was confirmed by culture and serological testing. In addition, lesions compatible with those caused by M. bovis were found by histopathological examination. These findings highlight the importance of the accurate diagnosis of tuberculosis and paratuberculosis for the effective control of both diseases.
authors: Departamento de Sanidad Animal y Medicina Preventiva, Facultad de Ciencias Veterinarias, Universidad Nacional del Centro de la Provincia de Buenos Aires, Argentina.
authors: M C
authors: MC
authors: Jorge
authors: D M
authors: DM
authors: Schettino
authors: P
authors: P
authors: Torres
authors: A
authors: A
authors: Bernardelli
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D005779:Immunodiffusion / Q000662:veterinary; D007428:Intradermal Tests / Q000662:veterinary; D016927:Mycobacterium avium subsp. paratuberculosis / Q000276:immunology; D009163:Mycobacterium bovis / Q000276:immunology; D010283:Paratuberculosis / Q000150:complications / Q000175:diagnosis*; D012756:Sheep; D012757:Sheep Diseases / Q000175:diagnosis*; D014374:Tuberculin Test / Q000662:veterinary; D014376:Tuberculosis / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*
chemical_list: D000907:Antibodies, Bacterial