Peritoneal fluid concentrations of interleukin-11 in women with endometriosis.
OBJECTIVE
To determine the peritoneal fluid concentrations of interleukin-11 (IL-11) in women with endometriosis as compared with the control group.


METHODS
A prospective, controlled study.


METHODS
The obstetrics and gynecology department of a teaching hospital and a university immunology department.


METHODS
Sixty consecutive women undergoing laparoscopic surgery for benign gynecological indications.


METHODS
Peritoneal fluid was obtained during laparoscopy, and the concentration of IL-11 was measured.


METHODS
Concentration of IL-11 in correlation with the presence of endometriosis, its stage, and the phase of the menstrual cycle.


RESULTS
IL-11 was detectable in the peritoneal fluid of 64% of women tested. Concentrations of IL-11 showed no correlation with the presence of endometriosis, the American Fertility Society stage of the disease, or the phase of the menstrual cycle.


CONCLUSIONS
We found no evidence to suggest that IL-11 is involved in the pathogenesis of pelvic endometriosis.
Gazvani
M R
MR
Reproductive Medicine Unit, Liverpool Women's Hospital, Liverpool, United Kingdom. m.r.gazvani@abdn.ac.uk
Bates
M
M
Vince
G
G
Christmas
S
S
Lewis-Jones
D I
DI
Kingsland
C
C
D000328:Adult; D001202:Ascitic Fluid / Q000378:metabolism*; D004715:Endometriosis / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D017370:Interleukin-11 / Q000378:metabolism*; D008597:Menstrual Cycle; D009994:Osmolar Concentration; D011446:Prospective Studies; D012016:Reference Values
D017370:Interleukin-11