title: Indocyanine green enhanced transpupillary thermotherapy of circumscribed choroidal haemangioma.
abstract: OBJECTIVE
  To investigate the effect of indocyanine green in enhancing the effect of diode laser for treatment of circumscribed choroidal haemangioma.
  
  
  METHODS
  Intravenous indocyanine green was used to enhance uptake of heat energy during transpupillary diode thermotherapy of circumscribed choroidal haemangioma.
  
  
  RESULTS
  In a series of 6 patients treated in this manner, response to treatment was much improved compared with results without the use of indocyanine green. All patients retained the same or better visual acuity after treatment, and 67% of eyes improved visual acuity by more than 2 lines on Snellen testing. Ultrasonographic and angiographic evidence of improvement was seen in all patients. Treatment complications were minimal, comprising transient worsening of preexisting cystoid macular oedema in one case, and a small macular branch vein occlusion in the retina overlying the treated area.
  
  
  CONCLUSIONS
  The use of indocyanine green as a contrast medium during transpupillary thermotherapy allows consistent uptake of diode laser energy, and shortens the duration of laser burn required. It is a cost-effective, easily performed outpatient procedure, with lower morbidity than other treatment modalities.
authors: Academic Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, UK.
authors: A
authors: A
authors: Kamal
authors: A R
authors: AR
authors: Watts
authors: I G
authors: IG
authors: Rennie
mesh_terms: D000328:Adult; D000368:Aged; D002830:Choroid Neoplasms / Q000628:therapy*; D004396:Coloring Agents / Q000627:therapeutic use; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006391:Hemangioma / Q000628:therapy*; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007208:Indocyanine Green / Q000627:therapeutic use*; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014792:Visual Acuity
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green