title: Keratosis lichenoides chronica: report of a case developing after erythroderma.
abstract: A 66-year-old male presented with keratosis lichenoides chronica after a presumed drug-induced erythroderma. After resolution of the erythroderma, slightly scaly erythematous and violaceous papules in a reticular arrangement over the trunk and limbs developed in association with hoarseness, palmoplantar keratoderma, onycholysis and subungual keratosis. Histology from a lichenoid lesion showed pseudo-epitheliomatous hyperplasia, hyperorthokeratosis, parakeratosis, dyskeratosis, neutrophil exocytosis and focal vacuolar degeneration of the basal layer of the epidermis. There was a band-like chronic inflammatory infiltrate in the upper dermis. The skin improved with prednisone 40 mg/day for 15 days, leaving atrophic hypopigmented scars. A diagnosis of keratosis lichenoides chronica was made.
authors: Unit of Dermatology, Hospital do Servidor Publico Estadual de Sao Paulo, Brazil. prcriado@uol.com.br
authors: P R
authors: PR
authors: Criado
authors: N Y
authors: NY
authors: Valente
authors: J A
authors: JA
authors: Sittart
authors: J M
authors: JM
authors: Juang
authors: C
authors: C
authors: Vasconcellos
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D003873:Dermatitis, Exfoliative / Q000150:complications* / Q000175:diagnosis; D005500:Follow-Up Studies; D006801:Humans; D007642:Keratosis / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D008010:Lichen Planus / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D008297:Male; D011241:Prednisone / Q000008:administration & dosage
chemical_list: D011241:Prednisone