Microbial pathogenesis: lipid rafts as pathogen portals.
The route of initial entry influences how host cells respond to intracellular pathogens. Recent studies have demonstrated that a wide variety of pathogens target lipid microdomains in host cell membranes, known as lipid rafts, to enter host cells as an infectious strategy.
Rosenberger
C M
CM
Biotechnology Laboratory and Department of Microbiology and Immunology, University of British Columbia, British Columbia V6T 1Z3, Vancouver, Canada.
Brumell
J H
JH
Finlay
B B
BB
D000818:Animals; D001419:Bacteria / Q000378:metabolism / Q000472:pathogenicity*; D021962:Membrane Microdomains / Q000378:metabolism / Q000382:microbiology / Q000502:physiology* / Q000821:virology; D014780:Viruses / Q000378:metabolism / Q000472:pathogenicity*