Primary left-atrial leiomyosarcoma.
A patient rapidly developing right heart failure due to a left-atrial leiomyosarcoma was admitted for surgery. A large tumor, originating in the left atrium and extending into both pulmonary veins, was removed. Histology showed an unusual epitheloid appearance of many cells with occasional mitoses and a strong immunexpression to desmin and actin. Six months later heart failure developed again: computer tomography demonstrated regrowth of the tumor in the left atrium with invasion of the mediastinum and the para-aortal lymph nodes. The patient died shortly after.
Fabricius
A M
AM
Division of Cardiovascular Surgery, Heart Center, University of Leipzig, Germany.
Autschbach
R
R
Lochhaas
L
L
Brose
S
S
Mohr
F W
FW
D000368:Aged; D006325:Heart Atria; D006338:Heart Neoplasms / Q000473:pathology*; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local