Evaluating presence/absence of target microbes in microbiological tests.
A typical qualitative microbiological method performance (collaborative) study gathers a data set of responses about a test for the presence or absence of a target microbe. We developed 2 models that estimate false-positive and false-negative rates. One model assumes a constant probability that the tests will indicate the target microbe is present for any positive concentration in the test portion. The other model assumes that this probability follows a logistic curve. Test results from several method performance studies illustrate these estimates.
Blodgett
R J
RJ
U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, Washington, DC 20204, USA.
Hitchins
A D
AD
D000465:Algorithms; D003611:Dairy Products / Q000382:microbiology; D005516:Food Microbiology; D016015:Logistic Models; D008460:Meat / Q000382:microbiology; D015233:Models, Statistical