title: Unusual manifestations of type II cryoglobulinaemia associated with Waldenström's macroglobulinaemia.
abstract: Cryoglobulinaemia in association with Waldenström's macroglobulinaemia is relatively common, ranging from 8% to 18% of cases; however, < 5% have symptoms or complications. We describe a patient with a history of cutaneous, peritoneal, and fallopian tube vasculitis related to type II cryoglobulinaemia associated with Waldenström's macroglobulinaemia. Cytotoxic treatment was initiated (cyclophosphamide, vincristine, and prednisone) and had a good initial response. However, after the third course of chemotherapy, the patient presented with septic shock and died. Even though cryoglobulinaemia is a model of systemic vasculitis, peritoneal and fallopian tube vasculitis associated with type II cryoglobulinemia has not been described previously.
authors: Service de Médecine Interne, Hôpital du Haut-levêque, Avenue de Magellan, 33604 Pessac, France.
authors: P
authors: P
authors: Blanco
authors: J F
authors: JF
authors: Viallard
authors: J
authors: J
authors: Rivel
authors: B
authors: B
authors: Leng
authors: J L
authors: JL
authors: Pellegrin
mesh_terms: D003449:Cryoglobulinemia / Q000209:etiology*; D005187:Fallopian Tubes / Q000098:blood supply; D005260:Female; D006801:Humans; D008875:Middle Aged; D010537:Peritoneum / Q000098:blood supply; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000209:etiology; D008258:Waldenstrom Macroglobulinemia / Q000150:complications*