title: The efficacy of 1 alpha hydroxy vitamin D3 treatment of the metabolic bone disorder in patients who underwent gastrectomy for gastric cancer.
abstract: OBJECTIVE
  The aim of this study was to elucidate the efficacy of 1 alpha hydroxy vitamin D3 for treatment of metabolic bone disorder after gastrectomy.
  
  
  METHODS
  MD-MS method was performed in 16 patients who underwent gastrectomy to evaluate the metabolic bone disorder and compared before and after 1 alpha hydroxy vitamin D3 treatment. The symp-toms related to the metabolic bone disorder were also analyzed through patient interview.
  
  
  RESULTS
  The severity of the metabolic bone disorder analyzed by the MD-MS method improved after 1 alpha hydroxy vitamin D3 treatment in 56.3% of patients. The deviation degree of the cortical bone density was also significantly improved. The symptoms related to metabolic bone disorder disappeared in 80% of patients after treatment.
  
  
  CONCLUSIONS
  The administration of 1 alpha hydroxy vitamin D3 may be useful for the metabolic bone disorder in the treatment of patients after gastrectomy.
authors: First Department of Surgery, Yokohama City University, School of Medicine, Japan.
authors: Y
authors: Y
authors: Rino
authors: T
authors: T
authors: Imada
authors: Y
authors: Y
authors: Yamamoto
authors: M
authors: M
authors: Takahashi
authors: T
authors: T
authors: Amano
authors: Y
authors: Y
authors: Takanashi
mesh_terms: D000368:Aged; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005743:Gastrectomy; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use*; D008297:Male; D011183:Postoperative Complications; D013274:Stomach Neoplasms / Q000601:surgery*
chemical_list: D006887:Hydroxycholecalciferols