Preparation of new anti-tubulin ligands through a dual-mode, addition-elimination reaction to a bromo-substituted alpha, beta-unsaturated sulfoxide.
Chen
Z
Z
Department of Chemistry and Biochemistry, P.O. Box 97348, Baylor University, Waco, Texas 76798, USA.
Mocharla
V P
VP
Farmer
J M
JM
Pettit
G R
GR
Hamel
E
E
Pinney
K G
KG
D001966:Bromine / Q000737:chemistry*; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012451:Safrole / Q000031:analogs & derivatives* / Q000737:chemistry*; D014404:Tubulin / Q000378:metabolism; D050257:Tubulin Modulators
D008024:Ligands; D014404:Tubulin; D050257:Tubulin Modulators; D012451:Safrole; D001966:Bromine; C005746:sulfoxide