Stability of disodium salt of inosine phosphate in aqueous solutions.
The HPLC method for the separation of the disodium salt of inosine phosphate (PIN) and the product of its transformation, inosine (IN) and hypoxanthine (HP) were developed and validated. The hydrolysis kinetics of disodium salt of inosine phosphate was studied in aqueous solution at 353 K over a pH range of 0.45-12.13.
Jelińska
A
A
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Karol Marcinkowski University of Medical Sciences, 6 Grunwaldzka Str., 60-780 Poznań, Poland.
Lewandowski
T
T
D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D019271:Hypoxanthine / Q000032:analysis; D007288:Inosine / Q000032:analysis; D007292:Inosine Nucleotides / Q000032:analysis*; D007700:Kinetics; D012996:Solutions; D014867:Water
D007292:Inosine Nucleotides; D012996:Solutions; D014867:Water; D019271:Hypoxanthine; D007288:Inosine