title: Lipid peroxidation induced by Clinostomum detruncatum in muscle of the freshwater fish Rhamdia quelen.
abstract: The effect of Clinostomum detruncatum metacercaria infection on the activities of the antioxidant enzymes superoxide dismutase and catalase in muscle of the freshwater fish Rhamdia quelen was analyzed. Tert-butyl hydroperoxide-initiated chemiluminescence, a measure of lipid peroxidation, was also investigated. Enzyme activities were similar in infected and uninfected fishes. However, the chemiluminescence was almost 2-fold higher in muscle of infected fishes than in muscle of uninfected ones. These results indicate that parasite infection induces oxidative stress and a higher level of membrane damage in the fish muscle due to an imbalance between pro-oxidants and non-enzymatic antioxidants. Our results suggest that fish response to parasite infection could involve, as in other vertebrates, reactive oxygen intermediates.
authors: Departamento de Parasitologia, Universidade Federal do Rio Grande do Sul, Porto Alegre-RS, Brazil.
authors: A R
authors: AR
authors: Belló
authors: E
authors: E
authors: Fortes
authors: A
authors: A
authors: Belló-Klein
authors: A A
authors: AA
authors: Belló
authors: S F
authors: SF
authors: Llesuy
authors: R B
authors: RB
authors: Robaldo
authors: A
authors: A
authors: Bianchini
mesh_terms: D000818:Animals; D001938:Brazil; D002374:Catalase / Q000032:analysis; D002397:Catfishes; D005393:Fish Diseases / Q000469:parasitology* / Q000473:pathology; D015227:Lipid Peroxidation; D008163:Luminescent Measurements; D018482:Muscle, Skeletal / Q000201:enzymology / Q000469:parasitology* / Q000473:pathology; D018384:Oxidative Stress; D012588:Scintillation Counting / Q000662:veterinary; D013482:Superoxide Dismutase / Q000032:analysis; D014200:Trematoda / Q000472:pathogenicity*; D014201:Trematode Infections / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*; D020122:tert-Butylhydroperoxide / Q000737:chemistry
chemical_list: D020122:tert-Butylhydroperoxide; D002374:Catalase; D013482:Superoxide Dismutase