title: Drug resistant tuberculosis.
abstract: The fact that M. tuberculosis develops resistance to anti-tuberculosis drugs has been known since the introduction of chemotherapy in 1952. Resistance has been reported to various drugs in India. Several factors pertaining to patients, physicians and environment are responsible for this. Clinical presentation of drug resistant tuberculosis is not different from drug responsive tuberculosis in children. Management of multi-drug resistant (MDR) tuberculosis is difficult and frustrating. Several second line drugs are being used. It is important to prevent this condition by adequate treatment of routine cases of tuberculosis and their contacts by directly observed therapy short course (DOTS).
authors.affiliation: Department of Pediatrics, Advanced Pediatric Centre, Post Graduate Institute of Medical Education and Research, Chandigarh.
authors.forename: M
authors.initials: M
authors.lastname: Singh
authors.forename: S
authors.initials: S
authors.lastname: Jayanthi
authors.forename: L
authors.initials: L
authors.lastname: Kumar
mesh_terms: D000617:Aminoglycosides / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use*; D002648:Child; D024841:Fluoroquinolones; D006801:Humans; D007194:India; D010349:Patient Compliance; D016133:Polymerase Chain Reaction; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control
chemical_list: D000617:Aminoglycosides; D000890:Anti-Infective Agents; D000995:Antitubercular Agents; D024841:Fluoroquinolones