Future perspectives on selective sentinel lymphadenectomy.
Selective sentinel lymphadenectomy is a standard staging procedure for patients with melanoma and is rapidly evolving into a standard procedure for breast cancer. A well-trained, multidisciplinary team is essential for the success of such a procedure. Clinical trials are under way to determine the clinical significance of sentinel lymph nodes in melanoma and breast cancer. The techniques of harvesting are being developed in other solid cancers, such as gynecologic and gastrointestinal cancer. Cellular and molecular techniques are being used to study the mechanism of micrometastasis.
Leong
S P
SP
Department of Surgery, University of California, San Francisco School of Medicine, UCSF Comprehensive Cancer Center, 94115, USA. leongs@surgery.ucsf.edu
Wong
J H
JH
D001943:Breast Neoplasms / Q000473:pathology*; D002986:Clinical Trials as Topic; D005260:Female; D005544:Forecasting; D005770:Gastrointestinal Neoplasms / Q000473:pathology; D005833:Genital Neoplasms, Female / Q000473:pathology; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology*; D008545:Melanoma / Q000473:pathology*; D009367:Neoplasm Staging / Q000379:methods / Q000706:statistics & numerical data / Q000639:trends*; D010348:Patient Care Team; D015203:Reproducibility of Results; D021701:Sentinel Lymph Node Biopsy / Q000379:methods / Q000706:statistics & numerical data / Q000639:trends*