title: Isolated extra-corporeal coronary perfusion circuit for use during off-pump coronary artery bypass grafting.
abstract: Cardiovascular surgery would not have developed into its present form without the heart-lung machine. In coronary artery bypass grafting (CABG), cardiopulmonary bypass allows accurate, all site, complete revascularization in a way convenient to the surgeon. The aim of this circuit is to find new ways to reduce invasiveness of CABG and to create new basis conditions for successful coronary bypass grafting on the beating heart. Manipulation of the heart compromises collateral coronary flow, especially to critically narrowed coronaries. This circuit standardizes our method for perfusing blood through the coronary bypass grafts with controlled positive pressure as each distal anastomosis is made, and it preserves collateral coronary flow, while facilitating construction of the remaining distal anastomoses.
authors.affiliation: Albert Einstein College of Medicine, Bronx, New York, USA.
authors.forename: K
authors.initials: K
authors.lastname: McCusker
authors.forename: V
authors.initials: V
authors.lastname: Venkatarmana
authors.forename: J
authors.initials: J
authors.lastname: Panopolous
authors.forename: W
authors.initials: W
authors.lastname: DeBois
authors.forename: C
authors.initials: C
authors.lastname: McCusker
authors.forename: D
authors.initials: D
authors.lastname: Sisto
mesh_terms: D002315:Cardiopulmonary Bypass / Q000295:instrumentation* / Q000379:methods; D006439:Hemodynamics; D006493:Heparin; D006801:Humans; D009204:Myocardial Revascularization / Q000295:instrumentation / Q000379:methods; D010477:Perfusion / Q000295:instrumentation* / Q000379:methods; D014481:United States
chemical_list: D006493:Heparin