title: Stroke, vascular risk factors and depression: Cross-sectional study in a UK Caribbean-born population.
abstract: BACKGROUND
  Stroke, hypertension and diabetes are common in older Caribbean-born populations in the UK who may be at risk of depression secondary to vascular disease.
  
  
  OBJECTIVE
  We examined the association between stroke, vascular risk factors and depression in a community-based Caribbean-born population aged 55-75 years.
  
  
  METHODS
  Vascular risk factors were identified by interview, examination and blood tests. Depression was categorised using the Geriatric Depression Scale. Disablement was assessed as a potential mediating factor.
  
  
  RESULTS
  Physical illness and disablement were strongly associated with depression, independent of disablement. Previous stroke was associated with depression, independent of disablement. No vascular risk factors were associated with depression.
  
  
  CONCLUSIONS
  The risk of depression associated with stroke was not explained by disablement. However, the hypothesis that vascular risk factors are important in the genesis of depression was not supported.
authors.affiliation: Section of Old Age Psychiatry, Institute of Psychiatry, London, UK.
authors.forename: R
authors.initials: R
authors.lastname: Stewart
authors.forename: M
authors.initials: M
authors.lastname: Prince
authors.forename: A
authors.initials: A
authors.lastname: Mann
authors.forename: M
authors.initials: M
authors.lastname: Richards
authors.forename: C
authors.initials: C
authors.lastname: Brayne
mesh_terms: D017677:Age Distribution; D000368:Aged; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000208:ethnology / Q000209:etiology*; D003925:Diabetic Angiopathies / Q000208:ethnology / Q000523:psychology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000208:ethnology / Q000523:psychology*; D008131:London / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D017678:Sex Distribution; D012923:Social Class; D020521:Stroke / Q000208:ethnology / Q000523:psychology*; D014900:West Indies / Q000208:ethnology