[Selection of a personal dry powder inhaler based on peak inspiratory flow measurements in selected groups of patients with bronchial obstruction].
Peak inspiratory flow rate (PIFR) in 165 COPD patients and 119 asthmatic children was investigated. In-Check set (peak inspiratory flow meter) which can mimic the internal resistance of some dry powder inhalers, e.g. Discus, Aerolizer and Turbuhaler, was used. All children and adults subjects achieved the minimum and optimum PIFR independently to bronchial obstruction when using Discus resistance. Optimum values of PIFR adequate for Turbuhaler resistance attained 57.4% of patients in both groups together. The worst results were observed in regard to Aerolizer resistance when only 21.1% of patients were able to achieve optimum PIFR. Checking actually PIFR may be useful before prescribing dry pressure inhaler for children and elderly COPD patients, especially in cases with bronchial obstruction. Discus can be optimally used by all patients despite of age and lung function.
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D000280:Administration, Inhalation; D000368:Aged; D016535:Bronchial Hyperreactivity / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D002648:Child; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000188:drug therapy* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009330:Nebulizers and Vaporizers; D010366:Peak Expiratory Flow Rate; D011208:Powders / Q000008:administration & dosage* / Q000009:adverse effects
D011208:Powders