title: Allogeneic bone marrow transplantation-related transmission of human T lymphotropic virus type I (HTLV-I).
abstract: We report here the first case report of bone marrow transplantation (BMT)-related transmission of human T lymphotropic virus type-I (HTLV-I). Antibodies against HTLV-I-associated antigens (anti-HTLV-I) were detected in the serum from the BMT recipient 12 days post BMT. IgG against gag core proteins (anti-p19 and anti-p24) appeared earlier than IgM against gag and env proteins (anti-p19, anti-p24 and anti-gp46) during seroconversion. The data presented here differs from blood transfusion-related seroconversion. This phenomenon may be due to the engraftment of anti-HTLV-I producing cells from the donor.
authors.affiliation: Second Department of Internal Medicine, Oita Medical University, Hasama-Oita, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kikuchi
authors.forename: E
authors.initials: E
authors.lastname: Ohtsuka
authors.forename: K
authors.initials: K
authors.lastname: Ono
authors.forename: T
authors.initials: T
authors.lastname: Nakayama
authors.forename: Y
authors.initials: Y
authors.lastname: Saburi
authors.forename: K
authors.initials: K
authors.lastname: Tezono
authors.forename: M
authors.initials: M
authors.lastname: Ogata
authors.forename: M
authors.initials: M
authors.lastname: Iwahashi
authors.forename: M
authors.initials: M
authors.lastname: Nasu
mesh_terms: D000293:Adolescent; D000741:Anemia, Aplastic / Q000628:therapy; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002353:Carrier State / Q000821:virology; D015481:HTLV-I Antibodies / Q000097:blood; D015490:HTLV-I Infections / Q000276:immunology / Q000635:transmission*; D015368:Human T-lymphotropic virus 1; D006801:Humans; D019520:Living Donors; D008297:Male
chemical_list: D015481:HTLV-I Antibodies