title: Five cases of ocular toxocariasis confirmed by serology.
abstract: We report 5 cases of ocular toxocariasis in Korean adults complaining of visual impairment along with floating or bubbling sensation. Fundoscopic examination revealed a retinal detachment along with exudate in 4 cases. They all showed typical reaction by ELISA and immunoblot against Toxocra excretory-secretory antigen. One case showed high level of anti-Toxocara IgE antibodies (34,000 Toxocara units/L) as well as increased level of serum total IgE antibodies and the specific IgE antibodies for 3 inhalant antigens, suggesting that high level of anti-Toxocara IgE antibodies was associated with an atopic status. Clinical manifestations were improved after the sequential use of steroids then mebendazole. We also suggest that ocular toxocariasis should be thoroughly investigated even when an evocative uniocular inflammatory lesion is encountered in peripheral retina without a systematic disease.
authors.affiliation: Department of Ophthalmology, Kangdong Sacred-Heart Hospital, College of Medicine, Hallym University, Seoul, 134-701, Korea.
authors.forename: S P
authors.initials: SP
authors.lastname: Park
authors.forename: I
authors.initials: I
authors.lastname: Park
authors.forename: H Y
authors.initials: HY
authors.lastname: Park
authors.forename: S U
authors.initials: SU
authors.lastname: Lee
authors.forename: S
authors.initials: S
authors.lastname: Huh
authors.forename: J F
authors.initials: JF
authors.lastname: Magnaval
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D000953:Antigens, Protozoan / Q000097:blood; D015415:Biomarkers / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007723:Korea; D007815:Larva Migrans / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D017166:Toxocara canis / Q000276:immunology
chemical_list: D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; D015415:Biomarkers; D007073:Immunoglobulin E