title: Access to pyrrolo- and pyrido[1,2-a]indole derivatives by intramolecular nitrone cycloadditions. Effect of steric factors on the regioselective product formation.
abstract: On starting from N-allyl-substituted 2-indolecarbaldehydes and exploiting the intramolecular nitrone cycloaddition methodology, we synthesized a number of the title fused-ring indole derivatives in racemic as well as enantiopure form.
authors.affiliation: Istituto di Chimica Organica della Facoltà di Farmacia dell'Università di Milano, via Venezian 21, 20133 Milano, Italy.
authors.forename: E M
authors.initials: EM
authors.lastname: Beccalli
authors.forename: G
authors.initials: G
authors.lastname: Broggini
authors.forename: C
authors.initials: C
authors.lastname: La Rosa
authors.forename: D
authors.initials: D
authors.lastname: Passarella
authors.forename: T
authors.initials: T
authors.lastname: Pilati
authors.forename: A
authors.initials: A
authors.lastname: Terraneo
authors.forename: G
authors.initials: G
authors.lastname: Zecchi
mesh_terms: D018360:Crystallography, X-Ray; D003500:Cyclization; D007202:Indicators and Reagents; D007211:Indoles / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D009589:Nitrogen Oxides / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism
chemical_list: D007202:Indicators and Reagents; D007211:Indoles; D009589:Nitrogen Oxides; C015388:nitrones