title: Obstetric and neonatal outcome in women with a history of recurrent miscarriage: a cohort study.
abstract: Obstetric and neonatal outcomes of women who had a history of recurrent miscarriage were compared with a control population from 1 January 1992 to 30 June 1998. Amongst a total of 162 pregnancies which progressed beyond 24 weeks gestation in women with a history of recurrent miscarriage, there were four perinatal deaths and 16 babies were admitted to the special care baby unit. The rates of preterm delivery (13%), small-for-gestational-age (13%), perinatal loss (2.5%) and Caesarean section (36%) were significantly (P < 0.05) higher than those of the control group (3.9, 2.1, 1 and 16.7% respectively). The ratio of male to female babies was equal. There was no significant difference in the incidence of hypertension or diabetes between the two groups. Patients with recurrent miscarriage represent a population at high risk of obstetric problems and close surveillance in the antenatal period is therefore required.
authors.affiliation: Jessop Hospital for Women and Division of Biomedical Sciences, Sheffield Hallam University, Sheffield, UK.
authors.forename: S
authors.initials: S
authors.lastname: Jivraj
authors.forename: B
authors.initials: B
authors.lastname: Anstie
authors.forename: Y C
authors.initials: YC
authors.lastname: Cheong
authors.forename: F M
authors.initials: FM
authors.lastname: Fairlie
authors.forename: S M
authors.initials: SM
authors.lastname: Laird
authors.forename: T C
authors.initials: TC
authors.lastname: Li
mesh_terms: D000026:Abortion, Habitual / Q000150:complications / Q000628:therapy*; D000328:Adult; D016022:Case-Control Studies; D002585:Cesarean Section; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007234:Infant, Premature; D007236:Infant, Small for Gestational Age; D008297:Male; D007752:Obstetric Labor, Premature; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology; D011256:Pregnancy Outcome