title: Successful prolonged cardiopulmonary resuscitation after a combined intoxication with a tricyclic antidepressant, a benzodiazepine and a neuroleptic.
abstract: We report the case of a patient who co-ingested a tricyclic antidepressant (amitriptyline), benzodiazepines (alprazolam and lormetazepam) and a neuroleptic drug (prothipendyl). Major neurologic and cardiac symptoms occurred including a prolonged cardiac arrest. The cardiopulmonary resuscitation phase was complicated by a haematoma of the liver treated by a left hepatectomy. The clinical features and management of this combined intoxication are discussed.
authors.affiliation: Department of Critical Care, University Hospital, Vrije Universiteit Brussel, Brussels, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Christiaens
authors.forename: H
authors.initials: H
authors.lastname: Lessire
authors.forename: I
authors.initials: I
authors.lastname: Dellers
authors.forename: B
authors.initials: B
authors.lastname: Denis
authors.forename: L
authors.initials: L
authors.lastname: Vankeerberghen
authors.forename: C
authors.initials: C
authors.lastname: Verborgh
mesh_terms: D000328:Adult; D000525:Alprazolam / Q000506:poisoning*; D000639:Amitriptyline / Q000506:poisoning*; D014151:Anti-Anxiety Agents / Q000506:poisoning*; D000929:Antidepressive Agents, Tricyclic / Q000506:poisoning*; D014150:Antipsychotic Agents / Q000506:poisoning*; D001569:Benzodiazepines; D016887:Cardiopulmonary Resuscitation; D004630:Emergencies; D005260:Female; D006801:Humans; D008140:Lorazepam / Q000031:analogs & derivatives* / Q000506:poisoning*; D013406:Suicide, Attempted; D013843:Thiazines / Q000506:poisoning*; D013997:Time Factors
chemical_list: D014151:Anti-Anxiety Agents; D000929:Antidepressive Agents, Tricyclic; D014150:Antipsychotic Agents; D013843:Thiazines; D001569:Benzodiazepines; D000639:Amitriptyline; C069248:prothipendyl; C023842:lormetazepam; D008140:Lorazepam; D000525:Alprazolam