title: Subcellular distribution of calponin and caldesmon in rat hippocampus.
abstract: Caldesmon and calponin are two actin- and calmodulin-binding proteins involved in the 'actin-linked' regulation of smooth muscle and non-muscle Mg(2+)-actin-activated myosin II ATPase activity. In the present report we show that caldesmon and calponin are present in the post-synaptic side of symmetric synapses and accumulate in the post-synaptic densities of asymmetric synapses. Caldesmon- and calponin-immunoreactivities are also observed at the plasma membrane of the hippocampal neurones. Finally, while caldesmon seems strictly distributed to neurones, acidic calponin is present in both neurones and astrocytes.
authors.affiliation: INMED/INSERM U29, Parc Scientifique de Luminy, 13009 Marseille Cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Agassandian
authors.forename: M
authors.initials: M
authors.lastname: Plantier
authors.forename: A
authors.initials: A
authors.lastname: Fattoum
authors.forename: A
authors.initials: A
authors.lastname: Represa
authors.forename: E
authors.initials: E
authors.lastname: der Terrossian
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000166:cytology; D002135:Calcium-Binding Proteins / Q000032:analysis*; D002148:Calmodulin-Binding Proteins / Q000032:analysis*; D003712:Dendrites / Q000648:ultrastructure; D004591:Electrophoresis, Polyacrylamide Gel; D006624:Hippocampus / Q000737:chemistry* / Q000166:cytology*; D007150:Immunohistochemistry; D008840:Microfilament Proteins; D009457:Neuroglia / Q000166:cytology / Q000648:ultrastructure; D009474:Neurons / Q000166:cytology* / Q000648:ultrastructure; D009836:Oligodendroglia / Q000166:cytology; D051381:Rats; D013569:Synapses / Q000648:ultrastructure; D000096985:Calponins
chemical_list: D002135:Calcium-Binding Proteins; D002148:Calmodulin-Binding Proteins; D008840:Microfilament Proteins; D000096985:Calponins