[A case of Mycoplasma pneumoniae encephalitis with elevated anti-galactocerebroside antibody titers in the cerebrospinal fluid].
Anti-galactocerebroside (anti-GC) antibody has recently been recognized as a possible demyelinating agent. On the 9th day of Mycoplasma pneumoniae (Mp) pneumonia, an 8-year-old boy had a seizure lasting three hours followed by loss of consciousness for 30 hours. Anti-GC antibody titers and myelin basic protein in the CSF were 1:640 and 8.1 ng/dl, respectively. There were no neurological sequelae. It is suggested that the degree of elevation of anti-GC antibody titers in CSF may not correlate well with the severity and neurological prognosis in Mp encephalitis.
Nakano
S
S
Department of Pediatrics, Ichikawa General Hospital, Tokyo Dental College, Ichikawa, Chiba.
Sugita
K
K
Tanaka
Y
Y
D000906:Antibodies / Q000134:cerebrospinal fluid*; D015415:Biomarkers; D002648:Child; D003711:Demyelinating Diseases / Q000276:immunology; D004660:Encephalitis / Q000209:etiology* / Q000276:immunology; D005699:Galactosylceramides / Q000276:immunology*; D006801:Humans; D008297:Male; D011019:Pneumonia, Mycoplasma / Q000150:complications* / Q000276:immunology; D011379:Prognosis
D000906:Antibodies; D015415:Biomarkers; D005699:Galactosylceramides