Effects of peroxidase therapy on functional state of the liver and phagocytes and blood cell counts in mice with experimental leprosy.
We studied the effects of long-term therapy with horseradish peroxidase administered orally to mice with experimental leprosy. Horseradish peroxidase stimulated phagocyte myeloperoxidase activity that correlated with their functional activity, reduced leukocytosis, and produced no adverse effects on the liver.
Maslov
A K
AK
Institute of Leprosy, Russian Ministry of Health, Astrakhan.
Luzhnova
S A
SA
D000818:Animals; D001772:Blood Cell Count; D006735:Horseradish Peroxidase / Q000494:pharmacology*; D007918:Leprosy / Q000097:blood / Q000503:physiopathology*; D008099:Liver / Q000187:drug effects* / Q000503:physiopathology; D051379:Mice; D008808:Mice, Inbred CBA; D008854:Microscopy, Electron; D009195:Peroxidase / Q000378:metabolism; D010586:Phagocytes / Q000187:drug effects* / Q000201:enzymology
D006735:Horseradish Peroxidase; D009195:Peroxidase