[Prostatic phyllodes tumor, a rare entity. Anatamo-clinical and immunohistochemical study of 1 case].
We report the case of a prostatic phyllodes tumor in a 47-year-old man. It measured 6 cm and was composed of a glandular component with leaf-like architecture, lined with two cellular layers, and a moderately cellular stromal component, with no atypia and no mitosis. Basal cells were marked with high-molecular-weight cytokeratin antibody (34BE12) and stromal cells were marked with anti-vimentin and for some of them with CD34 antibodies. Prostatic phyllodes tumor is a rare lesion with uncertain prognosis. Total surgical removal is necessary because malignant transformation to high-grade sarcoma has been reported. In our case the development of the tumor at the posterior side of the prostate, the lack of PSA immunoreactivity and the presence of mucinous glands, sometimes "endocervical-like", could suggest an origin from embryonic mullerian remnants in the prostatic utricle rather than urogenital sinus.
Chatelain
D
D
Service d'anatomie pathologique, CHRU Amiens, Place Victor Pauchet, 80054 Amiens Cedex.
Coppola
S
S
De Pinieux G
David
E
E
Viellefond
A
A
D018952:Antigens, CD34 / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D003557:Phyllodes Tumor / Q000737:chemistry* / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000737:chemistry* / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
D018952:Antigens, CD34; D014746:Vimentin; D007633:Keratins