En bloc heterotopic auxiliary liver and bilateral renal transplant in a patient with homozygous protein C deficiency.
An 8-year-old girl with homozygous protein C deficiency who had undergone maintenance dialysis since birth because of renal veins with thrombosis was treated with an en bloc heterotopic auxiliary liver and bilateral renal transplantation. The reconstitution of protein C activity by auxiliary liver transplantation facilitated successful renal transplantation.
Angelis
M
M
Department of Surgery, Division of Liver Transplant, University of Miami School of Medicine, Miami, Florida, USA.
Pegelow
C H
CH
Khan
F A
FA
Verzaro
R
R
Tzakis
A G
AG
D002648:Child; D002768:Choledochostomy; D005260:Female; D006720:Homozygote; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology* / Q000601:surgery*; D016030:Kidney Transplantation / Q000379:methods*; D016031:Liver Transplantation / Q000379:methods*; D010641:Phenotype; D020151:Protein C Deficiency / Q000150:complications* / Q000235:genetics / Q000601:surgery*; D006435:Renal Dialysis; D012082:Renal Veins; D016042:Transplantation, Heterotopic / Q000379:methods*; D020246:Venous Thrombosis / Q000209:etiology