title: [Analysis of 500 liver transplantations at Bellvitge Hospital, Spain].
abstract: BACKGROUND
  We present the experience of the liver transplantation program at the Hospital of Bellvitge with 500 transplantations performed during 15 years, to describe changes in liver transplantation observed throughout the time and to analyze the long term results.
  
  
  METHODS
  Five groups each one including 100 consecutive transplantations are studied.
  
  
  RESULTS
  The main indications were hepatocellular carcinoma (23%), alcoholic cirrhosis (22.8%), and post-hepatitis C cirrhosis (18.8%). Sixty-five retransplantations were performed in 59 patients (13%), being the more frequent indications arterial thrombosis (13 patients) and primary nonfunction of graft (10 patients). In 10 patients a hepatorenal transplantation was performed. In group I, the most frequent donor cause of death was cranial traumatism (80%), while in group V it was the vascular pathology (52%). There were other significative differences between these groups of patients (I vs V): patients with stage 2 or 3 from UNOS status (45 vs 19%), blood use (29.6 [26] vs 4.6 [5.3] PRBC), ICU stay (13 [13] vs 7.4 [11] days), hospital stay (40 [52] vs 23.7 [17] days), rejection rate (46 vs 20%) and primary graft nonfunction (9 vs 3%). However, the infection rates (48 vs 54.5%) and biliary tract complications (26 vs 20%) have not shown statistically significant differences. Actuarial one and 5-year survival are 83 and 70% respectively.
  
  
  CONCLUSIONS
  An important and progressive improvement of liver transplantation results has been observed. However, de novo tumours, hepatitis C virus recurrence and chronic rejection can limit long term results.
authors.affiliation: Unidad de Trasplante Hepático. Ciudad Sanitaria y Universitaria de Bellvitge. L'Hospitalet de Llobregat. Barcelona.
authors.forename: E
authors.initials: E
authors.lastname: Jaurrieta
authors.forename: L
authors.initials: L
authors.lastname: Casais
authors.forename: J
authors.initials: J
authors.lastname: Figueras
authors.forename: E
authors.initials: E
authors.lastname: Ramos
authors.forename: C
authors.initials: C
authors.lastname: Lama
authors.forename: A
authors.initials: A
authors.lastname: Rafecas
authors.forename: T
authors.initials: T
authors.lastname: Casanovas Taltavull
authors.forename: J
authors.initials: J
authors.lastname: Fabregat
authors.forename: X
authors.initials: X
authors.lastname: Xiol
authors.forename: J
authors.initials: J
authors.lastname: Torras
authors.forename: C
authors.initials: C
authors.lastname: Baliellas
authors.forename: A
authors.initials: A
authors.lastname: Sabaté
authors.forename: G
authors.initials: G
authors.lastname: Rufí
authors.forename: C
authors.initials: C
authors.lastname: Benasco
authors.forename: T
authors.initials: T
authors.lastname: Casanovas
authors.forename: T
authors.initials: T
authors.lastname: Serrano
authors.forename: S
authors.initials: S
authors.lastname: Gil-Vernet
authors.forename: I
authors.initials: I
authors.lastname: Sabaté
authors.forename: J
authors.initials: J
authors.lastname: Busquets
mesh_terms: D000367:Age Factors; D001658:Biliary Fistula / Q000453:epidemiology; D016913:Blood Component Transfusion / Q000706:statistics & numerical data; D002423:Cause of Death; D005260:Female; D006084:Graft Rejection / Q000453:epidemiology; D006526:Hepatitis C / Q000453:epidemiology; D006801:Humans; D007239:Infections / Q000453:epidemiology; D007902:Length of Stay; D016031:Liver Transplantation / Q000401:mortality / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D015397:Program Evaluation; D012086:Reoperation; D013030:Spain / Q000453:epidemiology; D013927:Thrombosis / Q000453:epidemiology; D014019:Tissue Donors