Effects of ubiquinone-10 on energy metabolism and lipid peroxidation in rats with myocardial ischemia.
Preventive and therapeutic intraventricular administration of ubiquinone-10 to male rats with epinephrine-induced myocarditis increased the rate of oxidative phosphorylation, elevated the content of ATP, and inhibited lipid peroxidation in ischemic myocardium.
Krylov
V N
VN
Department of Human and Animal Physiology and Biochemistry, NI Lobachevskii Nizhny Novgorod State Medical University.
Luk'yanova
L D
LD
Koryagin
A S
AS
Yastrebova
E V
EV
D000244:Adenosine Diphosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D004734:Energy Metabolism / Q000187:drug effects*; D007700:Kinetics; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D017202:Myocardial Ischemia / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D051381:Rats; D014451:Ubiquinone / Q000494:pharmacology*
D014451:Ubiquinone; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; C025204:Ubiquinone Q2