title: Primary viscocanalostomy versus trabeculectomy in white patients with open-angle glaucoma: A randomized clinical trial.
abstract: OBJECTIVE
  To compare viscocanalostomy, a nonpenetrating procedure for glaucoma treatment, with trabeculectomy.
  
  
  METHODS
  Randomized controlled trial.
  
  
  METHODS
  Twenty white subjects (20 eyes) with open-angle glaucoma with no history of surgery were enrolled.
  
  
  METHODS
  Ten subjects were randomly assigned to viscocanalostomy according to Stegmann's technique and 10 subjects to a modified Cairns trabeculectomy. A complete ophthalmologic examination was performed the day before surgery and postoperatively. Further visits were scheduled monthly for 6 to 8 months after surgery.
  
  
  METHODS
  Success was defined as intraocular pressure (IOP) between 7 and 20 mmHg, with no medication.
  
  
  RESULTS
  After a mean follow-up of 6 months (range, 6-8 months), success was obtained in 5 of 10 cases in the trabeculectomy group and in no case in the viscocanalostomy group. With Kaplan-Meier's method, subjects with viscocanalostomy showed shorter postoperative IOP-reduction periods than subjects undergoing trabeculectomy.
  
  
  CONCLUSIONS
  According to the results of this short-term study, trabeculectomy was more effective than viscocanalostomy in lowering IOP in glaucomatous eyes of white patients.
authors.affiliation: Department of Ophthalmology, University of Cologne, Cologne, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Jonescu-Cuypers
authors.forename: P
authors.initials: P
authors.lastname: Jacobi
authors.forename: W
authors.initials: W
authors.lastname: Konen
authors.forename: G
authors.initials: G
authors.lastname: Krieglstein
mesh_terms: D000328:Adult; D000368:Aged; D000869:Anterior Eye Segment / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000208:ethnology / Q000601:surgery*; D006068:Gonioscopy; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013524:Surgical Flaps; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome; D044465:White People
chemical_list: D006820:Hyaluronic Acid