title: Effect of ascorbate and alpha-tocopherol on resistance of beta-carotene to oxidation.
abstract: The efficiency of ascorbate and alpha-tocopherol as stabilizers of beta-carotene, which is widely used in complex therapy and prevention of some diseases accompanied by oxidative stress, was studied. The latency of induced beta-carotene oxidation linearly depends on ascorbate concentration, while steady-state rate nonlinearly depends on the concentration of alpha-tocopherol, which attests to involvement of antioxidants in various stages of chain oxidation of beta-carotene.
authors.affiliation: Laboratory of Physical and Chemical Basis of Cell Metabolsim Control, NM Emanuel' Institute of Biochemical Physics, Russian Academy of Sciences, Moscow. chembio@glasnet.ru
authors.forename: A I
authors.initials: AI
authors.lastname: Kozachenko
authors.forename: S M
authors.initials: SM
authors.lastname: Gurevich
authors.forename: L G
authors.initials: LG
authors.lastname: Nagler
mesh_terms: D001205:Ascorbic Acid / Q000737:chemistry*; D007700:Kinetics; D010084:Oxidation-Reduction; D014810:Vitamin E / Q000737:chemistry*; D019207:beta Carotene / Q000737:chemistry*
chemical_list: D019207:beta Carotene; D014810:Vitamin E; D001205:Ascorbic Acid