title: Cardiac power output during transition from mechanical to spontaneous ventilation in canines.
abstract: Hemodynamic instability during weaning from mechanical ventilation is one proposed cause of weaning failure. This study evaluated cardiac power output (CPO) as an indicator of significant hemodynamic alteration and cardiac reserve during the transition from controlled mechanical ventilation to spontaneous ventilation using three clinical weaning modes. It also compared CPO with commonly used indicators of hemodynamic instability during weaning. The data suggest that CPO is a sensitive indicator of significant hemodynamic alteration and could be used to optimize cardiovascular function during weaning from mechanical ventilation to increase the likelihood of weaning success. Key words: cardiac output, cardiac power output, hemodynamic monitoring, mechanical ventilation
authors.affiliation: College of Nursing, The Ohio State University, Columbus, USA.
authors.forename: S K
authors.initials: SK
authors.lastname: Frazier
authors.forename: D K
authors.initials: DK
authors.lastname: Moser
authors.forename: K S
authors.initials: KS
authors.lastname: Stone
mesh_terms: D000818:Animals; D002302:Cardiac Output / Q000502:physiology*; D002407:Catheterization, Swan-Ganz; D004195:Disease Models, Animal; D004285:Dogs; D006333:Heart Failure / Q000139:chemically induced / Q000503:physiopathology*; D006439:Hemodynamics; D008297:Male; D011669:Pulmonary Wedge Pressure / Q000502:physiology*; D011897:Random Allocation; D015300:Ventilator Weaning