title: Specific passive immunity reduces the excretion of glycoprotein E-negative bovine herpesvirus type 1 vaccine strain in calves.
abstract: We investigated the excretion of either a glycoprotein E (gE)-negative bovine herpesvirus type 1 (BHV1) vaccine strain or a conventional modified-live vaccine strain in both naïve and passively immunised calves. The replication of gE-negative strain was considerably reduced in the maternally immunised calves, in comparison with the non-immune calves. On the other hand, the excretion of the gE-positive conventional vaccine strain was not reduced and even seemed to be prolonged in the presence of maternal antibodies. These results suggest that BHV1 gE may play a role in virus survival in the presence of antibodies.
authors.affiliation: Department of Infectious and Parasitic Diseases, Virology and Immunology, Faculty of Veterinary Medicine, University of Liège, Boulevard de Colonster, 20-B 43bis, 4000, Liège, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Lemaire
authors.forename: E
authors.initials: E
authors.lastname: Hanon
authors.forename: F
authors.initials: F
authors.lastname: Schynts
authors.forename: G
authors.initials: G
authors.lastname: Meyer
authors.forename: E
authors.initials: E
authors.lastname: Thiry
mesh_terms: D000818:Animals; D002417:Cattle; D007242:Herpesvirus 1, Bovine / Q000276:immunology*; D022283:Herpesvirus Vaccines / Q000276:immunology*; D007116:Immunization, Passive; D014759:Viral Envelope Proteins / Q000502:physiology*; D014764:Viral Proteins
chemical_list: D022283:Herpesvirus Vaccines; D014759:Viral Envelope Proteins; D014764:Viral Proteins; C046998:bovine herpesvirus type-1 glycoproteins