title: Effect of subthalamic nucleus stimulation on levodopa-induced dyskinesia in Parkinson's disease.
abstract: Article abstract-The authors studied the effect of bilateral subthalamic nucleus stimulation on levodopa-induced dyskinesias in 24 consecutive parkinsonian patients with disabling dyskinesias. The improvement in the three subtypes of levodopa-induced dyskinesias was significant from the third postoperative month and was mainly due to the decrease in the daily dose of levodopa allowed by the stimulation-induced improvement in the motor score.
authors.affiliation: Department of Clinical and Biological Neurosciences, University Hospital of Grenoble, and INSERM U318, Joseph Fourier University, France.
authors.forename: V
authors.initials: V
authors.lastname: Fraix
authors.forename: P
authors.initials: P
authors.lastname: Pollak
authors.forename: N
authors.initials: N
authors.lastname: Van Blercom
authors.forename: J
authors.initials: J
authors.lastname: Xie
authors.forename: P
authors.initials: P
authors.lastname: Krack
authors.forename: A
authors.initials: A
authors.lastname: Koudsie
authors.forename: A L
authors.initials: AL
authors.lastname: Benabid
mesh_terms: D000328:Adult; D000368:Aged; D004409:Dyskinesia, Drug-Induced / Q000209:etiology*; D004558:Electric Stimulation; D005260:Female; D006801:Humans; D007980:Levodopa / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000628:therapy*; D013787:Thalamic Nuclei / Q000503:physiopathology*
chemical_list: D007980:Levodopa