Accumulation of exogenous histone in rat brain parenchyma.
In vivo histoautoradiographic study of cerebral accumulation of exogenous histone after its intracarotid infusion to anesthetized rats with intact liver and animals with experimental cirrhosis showed that histone penetrates brain capillary endotheliocyte membranes and gets into the nervous tissue.
Gorukhina
O A
OA
Department of Biochemistry, AA Ukhtomsky Institute of Physiology, St Petersburg State University.
Ilyuk
R D
RD
Mishchenko
I V
IV
D000818:Animals; D001345:Autoradiography; D001812:Blood-Brain Barrier; D001921:Brain / Q000378:metabolism*; D006657:Histones / Q000008:administration & dosage / Q000378:metabolism*; D008099:Liver / Q000378:metabolism / Q000502:physiology; D008106:Liver Cirrhosis, Experimental / Q000378:metabolism / Q000503:physiopathology; D051381:Rats
D006657:Histones