title: [Metaphylaxis of nephrolithiasis].
abstract: Etiological factors and pathogenetic mechanisms were studied in 538 patients with nephrolithiasis. By composition of uroliths and salts, all the patients were divided into groups by types of urolithiasis (oxalate, urate, phosphate, cystic and mixed). After elimination of the uroliths using different methods, metaphylaxis of nephrolithiasis was conducted in all the patients. It varied with type of lithogenesis, etiology and pathogenesis. Antirecurrence therapy included diet with restriction of lithogenic substances, endogenic reduction of lithogenic metabolites and measures to decrease and block crystallization and lithogenesis. The treatment has diminished the incidence of recurrences from 32.3 to 9.6% (total), from 14.4 to 5.3% (in oxalate type), 47.2 to 16.9% (in phosphate type), 39.7 to 6.7% (in urate type), 40.5 to 17.7% (in mixed type).
authors.forename: M A
authors.initials: MA
authors.lastname: Uzdenov
mesh_terms: D000328:Adult; D000863:Antacids / Q000627:therapeutic use*; D004032:Diet / Q000379:methods*; D004359:Drug Therapy, Combination; D012968:Etidronic Acid / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015994:Incidence; D007669:Kidney Calculi / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D008277:Magnesium Oxide / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055502:Secondary Prevention; D014815:Vitamins / Q000627:therapeutic use*
chemical_list: D000863:Antacids; D014815:Vitamins; D008277:Magnesium Oxide; D012968:Etidronic Acid