title: Biomarkers of oxidative stress: an analytical approach.
abstract: Oxidative stress is implicated in many pathological processes and results from a disruption of the prooxidant/antioxidant balance. This review will focus on noninvasive biomarkers of radical-induced damage in biological fluids and particularly in blood. Special attention will be addressed to new analytical methods for the measurement of radical-mediated alterations in the integrity of lipids, proteins and DNA.
authors.affiliation: Department of Biochemistry, Pharmacology and Toxicologie, Versailles Hospital, Le Chesnay, France.
authors.forename: P
authors.initials: P
authors.lastname: Thérond
authors.forename: D
authors.initials: D
authors.lastname: Bonnefont-Rousselot
authors.forename: A
authors.initials: A
authors.lastname: Davit-Spraul
authors.forename: M
authors.initials: M
authors.lastname: Conti
authors.forename: A
authors.initials: A
authors.lastname: Legrand
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D015415:Biomarkers / Q000032:analysis / Q000097:blood*; D004247:DNA / Q000032:analysis / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D008055:Lipids / Q000032:analysis; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000502:physiology*; D011506:Proteins / Q000032:analysis / Q000378:metabolism; D012680:Sensitivity and Specificity
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D008055:Lipids; D011506:Proteins; D004247:DNA