title: [Advantage of screening for for infection in suddden and progressive hearing loss].
abstract: OBJECTIVE
  The aim of this retrospective study was to assess the advantage of systematic screening for infection in patients presenting with sudden or progressive sensorineural hearing loss.
  
  
  METHODS
  175 patients were included. 102 patients presented with unilateral sudden sensorineural hearing loss and 73 with progressive sensorineural hearing loss. Serologies tested were herpes simplex and zoster (IgM and IgG titres), Lyme disease (ELISA), syphilis (FTA-abs and MHA-TP) and HIV.
  
  
  RESULTS
  Screening for infection was negative in 172 patients. 2 patients had positive serology for Lyme disease and one for syphilis. The case of serological syphilis was finally diagnosed as latent syphilis after ruling out neurosyphilis. Both cases of suspected Lyme disease were later invalidated by Western blot and lumbar puncture (2 false positives).
  
  
  CONCLUSIONS
  Screening for infection was positive only in 1/175 patients (0.6%), rendering diagnosis of latent syphilis possible. These results suggest that, on grounds of cost-effectiveness, testing for infection should be limited to and focused on patients with a positive clinical evaluation.
authors.affiliation: Service d'ORL et de chirurgie cervico-faciale, CHUV, Lausanne. Joel.Gagnebin@chuv.hospvd.ch
authors.forename: J
authors.initials: J
authors.lastname: Gagnebin
authors.forename: R
authors.initials: R
authors.lastname: Maire
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018450:Disease Progression; D005260:Female; D007839:Functional Laterality; D015658:HIV Infections / Q000150:complications; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000382:microbiology / Q000503:physiopathology*; D006561:Herpes Simplex / Q000150:complications; D006562:Herpes Zoster / Q000150:complications; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008193:Lyme Disease / Q000150:complications; D008297:Male; D008875:Middle Aged; D013587:Syphilis / Q000150:complications* / Q000175:diagnosis; D014777:Virus Diseases / Q000150:complications* / Q000175:diagnosis
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M