Evolution of drug resistance and interpretation of drug sensitivity test.
Though with the advent of more and more numbers of antibiotics, infection control has become easier but it has been established more resistant strains of microbes are appearing. These resistant strains are becoming major public health problem. Drug misuse is one of the factors for resistant strains. While discussing mechanisms of drug resistance, gene transfer plays an important part. Drug resistance can be prevented by taking several strategies. There are several methods for performing antibiotic sensitivity test e.g., diffusion methods and dilution methods which are discussed elaborately.
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All India Institute of Hygiene and Public Health, Calcutta 700073.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003141:Communicable Diseases / Q000188:drug therapy* / Q000382:microbiology; D018432:Drug Resistance, Multiple; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D018570:Risk Assessment; D012680:Sensitivity and Specificity
D000900:Anti-Bacterial Agents