title: Ruthenium-catalyzed oxidation of alkanes with tert-butyl hydroperoxide and peracetic acid
abstract: The ruthenium-catalyzed oxidation of alkanes with tert-butyl hydroperoxide and peracetic acid gives the corresponding ketones and alcohols highly efficiently at room temperature. The former catalytic system, RuCl(2)(PPh(3))(3)-t-BuOOH, is preferable to the oxidation of alkylated arenes to give aryl ketones. The latter system, Ru/C-CH(3)CO(3)H, is suitable especially for the synthesis of ketones and alcohols from alkanes. The ruthenium-catalyzed oxidation of cyclohexane with CH(3)CO(3)H in trifluoroacetic acid/CH(2)Cl(2) at room temperature gave cyclohexyl trifluoroacetate and cyclohexanone with 90% conversion and 90% selectivity (85:15). The mechanistic study indicates that these catalytic oxidations of hydrocarbons involve oxo-ruthenium species as key intermediates.
authors.affiliation: Department of Chemistry, Graduate School of Engineering Science, Osaka University, 1-3, Machikaneyama, Toyonaka, Osaka 560-8531, Japan.
authors.initials: SI
authors.lastname: Murahashi
authors.initials: N
authors.lastname: Komiya
authors.initials: Y
authors.lastname: Oda
authors.initials: T
authors.lastname: Kuwabara
authors.initials: T
authors.lastname: Naota