title: Aneurysmal bone cyst of the mobile spine: report on 41 cases.
abstract: METHODS
  Forty-one cases of aneurysmal bone cyst of the mobile spine were retrospectively reviewed.
  
  
  OBJECTIVE
  To evaluate the role of surgical and nonsurgical treatment of aneurysmal bone cyst of the spine.
  
  
  BACKGROUND
  Ten to 30% of aneurysmal bone cysts arise from the mobile spine, frequently occurring in pediatric patients. The course of the disease depends on the aggressiveness of the tumor, as well as the treatment. Intralesional surgery seems to be an effective treatment, as well as radiotherapy and embolization.
  
  
  METHODS
  All charts, radiographs, and images were reviewed. The composite information provided by this review allowed for oncologic and surgical staging of these cases. Thirty-two patients underwent curettage (14 of them followed by radiotherapy), four were submitted to selective arterial embolization, three received radiotherapy alone, and two underwent en bloc-excision.
  
  
  RESULTS
  All patients were found alive and disease free at final follow-up evaluation. Two recurrences followed one incomplete curettage and one embolization. The combination of curettage and radiotherapy, although effective, showed the greatest incidence of late axial deformity. Selective arterial embolization was curative in three of four cases and did not affect the possibility of surgery in case of local recurrence.
  
  
  CONCLUSIONS
  If confirmed on larger series, selective arterial embolization seems to be the first treatment option for spine aneurysmal bone cyst, because of the low cost-to-benefit ratio. Diagnosis must be certain, based on pathognomonic radiographic pattern or on histologic study.- In case of neurologic involvement, pathologic fracture, technical impossibility of performing embolization, or local recurrence after at least two embolization procedures, complete intralesional excision would be the therapy of choice.
authors.affiliation: Department of Orthopedics and Traumatology, Maggiore Hospital, Bologna, Italy. boriani@tizeta.it
authors.forename: S
authors.initials: S
authors.lastname: Boriani
authors.forename: F
authors.initials: F
authors.lastname: De Iure
authors.forename: L
authors.initials: L
authors.lastname: Campanacci
authors.forename: A
authors.initials: A
authors.lastname: Gasbarrini
authors.forename: S
authors.initials: S
authors.lastname: Bandiera
authors.forename: R
authors.initials: R
authors.lastname: Biagini
authors.forename: F
authors.initials: F
authors.lastname: Bertoni
authors.forename: P
authors.initials: P
authors.lastname: Picci
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D017824:Bone Cysts, Aneurysmal / Q000000981:diagnostic imaging / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000000981:diagnostic imaging / Q000628:therapy*