Cushing's syndrome from Klack's solution.
OBJECTIVE
To report, for the first time, a case of Cushing's syndrome from the use of Klack's solution, a multipurpose remedy composed of various pharmaceutical agents with a glucocorticoid as one of the active ingredients.


METHODS
A case report of Cushing's syndrome is presented, and the different components of Klack's solution are compared.


RESULTS
In a 36-year-old man with the development of Cushing's syndrome, the use of Klack's solution for the treatment of oral lichen planus was incriminated. For the evaluation of Cushing's syndrome, all potential sources and doses of corticosteroids, as well as the patient's compliance with dosing instructions, must be examined. In this case, the Klack's solution, which can be prepared in multiple versions and strengths at the discretion of the prescriber, had a high content of corticosteroid.


CONCLUSIONS
Health-care providers should be reminded of the potency and potential harm of corticosteroids by this unusual case of Cushing's syndrome attributable to Klack's solution.
Lankford
H V
HV
Endocrine and Diabetes Management Center Inc, 7231 Forest Ave, Suite 103, Richmond, VA 23226, USA.
D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000032:analysis; D000328:Adult; D003480:Cushing Syndrome / Q000139:chemically induced* / Q000188:drug therapy; D003907:Dexamethasone / Q000627:therapeutic use; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000737:chemistry / Q000627:therapeutic use; D005905:Glyburide / Q000627:therapeutic use; D006801:Humans; D017676:Lichen Planus, Oral / Q000188:drug therapy; D008297:Male
D000305:Adrenal Cortex Hormones; D005938:Glucocorticoids; D003907:Dexamethasone; D005905:Glyburide