title: Neurocutaneous melanosis associated with Dandy-Walker malformation. case report and review of the literature.
abstract: Neurocutaneous melanosis is a rare dysmorphogenesis associated with single or multiple giant pigmented cutaneous nevi and diffuse involvement of the leptomeninges anywhere in the central nervous system (CNS). It is interesting that almost 8-10% of patients had associated Dandy-Walker malformation in the literature, suggesting a common origin of the developmental abnormalities. In this article, we present a 2-year-old patient with neurocutaneous melanosis associated with Dandy-Walker malformation. We reviewed the literature and discuss the pathogenesis based on the preferred hypotheses so far.
authors.affiliation: Neurosurgery Department, Hacettepe University, School of Medicine, Ankara, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Berker
authors.forename: H H
authors.initials: HH
authors.lastname: Oruckaptan
authors.forename: H K
authors.initials: HK
authors.lastname: Oge
authors.forename: K
authors.initials: K
authors.lastname: Benli
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D002675:Child, Preschool; D003616:Dandy-Walker Syndrome / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008548:Melanosis / Q000150:complications* / Q000175:diagnosis; D020752:Neurocutaneous Syndromes / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D017287:Ventriculoperitoneal Shunt