title: Quality of life measures in the Miami HIV-1 infected drug abusers cohort: relationship to gender and disease status.
abstract: OBJECTIVE
  This study examined activity, daily living, health, support, and outlook in HIV+ drug users.
  
  
  METHODS
  Using the physician-administered Spitzer Index, the study assessed 75 HIV-1 seropositive men (n = 51) and women (n = 24) enrolled in the Miami HIV-1 Infected Drug Abusers Study (MIDAS).
  
  
  RESULTS
  Total composite scores were significantly lower in the HIV-1 infected women than the men (p = .03). Significant gender differences were observed in activity assessment, independent of disease status, with women six times as likely to have lower activity scores (p = .0038). Most women (45%) in this category were homeless or marginally housed, compared to 11 percent of the men. Additionally, women with low activity scores had less social support than women with high activity scores. Cocaine use was significantly related to reports of normal activity, and varied across genders; more men used cocaine than women (p = .03). Compared to non-AIDS participants, AIDS patients were more likely to have lower scores in health (p = .009) and poorer outlook (p = .03).
  
  
  CONCLUSIONS
  These findings reveal specific deficits in areas of psychosocial capacity, particularly in HIV-1 infected women who abuse drugs, that may need to be strengthened in order to enhance function and adherence to treatment, as well as well-being.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, 1400 N.W. 10th Avenue, 6th Floor (D21), Miami, FL 33136, USA. gshor@med.miami.edu
authors.forename: G
authors.initials: G
authors.lastname: Shor-Posner
authors.forename: R
authors.initials: R
authors.lastname: Lecusay
authors.forename: M J
authors.initials: MJ
authors.lastname: Miguez-Burbano
authors.forename: J
authors.initials: J
authors.lastname: Quesada
authors.forename: A
authors.initials: A
authors.lastname: Rodriguez
authors.forename: P
authors.initials: P
authors.lastname: Ruiz
authors.forename: S
authors.initials: S
authors.lastname: O'Mellan
authors.forename: A
authors.initials: A
authors.lastname: Campa
authors.forename: H
authors.initials: H
authors.lastname: Rincon
authors.forename: F
authors.initials: F
authors.lastname: Wilkie
authors.forename: J B
authors.initials: JB
authors.lastname: Page
authors.forename: M K
authors.initials: MK
authors.lastname: Baum
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology; D000328:Adult; D005260:Female; D005431:Florida; D015658:HIV Infections / Q000523:psychology*; D015497:HIV-1; D006703:Ill-Housed Persons / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012803:Sick Role; D012944:Social Support; D019966:Substance-Related Disorders / Q000523:psychology*