Circulating adhesion molecules in patients with vibration-induced white finger.
We investigated whether a relationship existed between soluble adhesion molecules and vascular damage from vibration-induced white finger. Thirty-five men exposed to vibration and 40 healthy control subjects were examined. Concentrations of soluble E-selectin intercellular adhesion molecules, and vascular cell adhesion molecules in serum were measured with sandwich enzyme-linked adhesion immunosorbent assay. Neither E-selectin nor intercellular adhesion molecule levels are elevated in men exposed to vibration with white finger compared to levels in men exposed to vibration without white finger and control subjects. The serum level of soluble vascular cell adhesion molecules is significantly increased in patients with vibration-induced white finger.
Kurozawa
Y
Y
Department of Public Health, Faculty of Medicine, Tottori University, and the Vibration Syndrome Center, San-in Rosai Hospital, Yonago, Japan. kurozawa@grape.med.tottori-u.ac.jp
Nasu
Y
Y
D000368:Aged; D000369:Aged, 80 and over; D015815:Cell Adhesion Molecules / Q000097:blood*; D019040:E-Selectin / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood; D008297:Male; D009784:Occupational Diseases / Q000097:blood*; D011928:Raynaud Disease / Q000097:blood* / Q000209:etiology; D019010:Vascular Cell Adhesion Molecule-1 / Q000097:blood; D014732:Vibration / Q000009:adverse effects*
D015815:Cell Adhesion Molecules; D019040:E-Selectin; D019010:Vascular Cell Adhesion Molecule-1; D018799:Intercellular Adhesion Molecule-1