title: Systemic Exophiala jeanselmei infection in a cat.
abstract: A 14-year-old spayed domestic shorthair cat was referred for ultrasonographic evaluation of abnormally shaped kidneys. Multifocal lesions were detected ultrasonographically in the liver and kidneys; a fine-needle aspirate of the kidneys was performed, and numerous clumps of fungal hyphae were identified. The following day, the cat was recumbent with advanced neurologic signs. The cat was euthanatized, and a necropsy was performed. Multifocal granuloma-like masses were seen on the liver, kidneys, abdominal wall, mesentery, thoracic wall, pericardium, and epicardium. Similar lesions were found on the cervical portion of the spinal cord, the cerebrum, and cerebellum. Exophiala jeanselmei, an organism of the phaeohyphomycotic group, was identified on fungal culture. To our knowledge, systemic infections caused by this organism have not been reported. However, phaeohyphomycotic infections are believed to be an emerging disease in humans.
authors.affiliation: Unifour Veterinary Referrals, Hickory, NC 28602, USA.
authors.forename: S R
authors.initials: SR
authors.lastname: Helms
authors.forename: C G
authors.initials: CG
authors.lastname: McLeod
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D000818:Animals; D001921:Brain / Q000382:microbiology / Q000473:pathology; D002371:Cat Diseases / Q000382:microbiology* / Q000473:pathology*; D002415:Cats; D005093:Exophiala / Q000472:pathogenicity*; D017809:Fatal Outcome; D005260:Female; D007552:Isotonic Solutions / Q000008:administration & dosage; D007668:Kidney / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D008099:Liver / Q000382:microbiology / Q000473:pathology; D008643:Mesentery / Q000382:microbiology / Q000473:pathology; D009181:Mycoses / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D000077331:Ringer's Solution; D018746:Systemic Inflammatory Response Syndrome / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D014463:Ultrasonography; D016482:Urinalysis / Q000662:veterinary
chemical_list: D007552:Isotonic Solutions; D000077331:Ringer's Solution