title: Acinetobacter baumannii at a tertiary-care teaching hospital in Jerusalem, Israel.
abstract: In a retrospective 10-year analysis of 3,536 patient-unique isolates, Acinetobacter baumannii imipenem susceptibility declined from 98.1 (1990) to 64.1% (2000), and ciprofloxacin susceptibility decreased from 50.5 to 13.1%. Imipenem median zone diameters decreased from 27. 7 (1997) to 18.8 mm (2000). No outbreaks were detected. Two clusters were identified for 41 strains genotyped by pulsed-field gel electrophoresis, but imipenem resistance was not clonal.
authors.affiliation: Department of Clinical Microbiology & Infectious Diseases, Hadassah-University Hospital, Jerusalem, Israel. simhon@hadassah.org.il
authors.forename: A
authors.initials: A
authors.lastname: Simhon
authors.forename: G
authors.initials: G
authors.lastname: Rahav
authors.forename: G
authors.initials: G
authors.lastname: Shazberg
authors.forename: C
authors.initials: C
authors.lastname: Block
authors.forename: H
authors.initials: H
authors.lastname: Bercovier
authors.forename: M
authors.initials: M
authors.lastname: Shapiro
mesh_terms: D000150:Acinetobacter / Q000187:drug effects* / Q000235:genetics; D000151:Acinetobacter Infections / Q000453:epidemiology / Q000382:microbiology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D004352:Drug Resistance, Microbial / Q000235:genetics; D016521:Electrophoresis, Gel, Pulsed-Field; D006784:Hospitals, Teaching; D006801:Humans; D015378:Imipenem / Q000494:pharmacology*; D007557:Israel / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D012189:Retrospective Studies; D013845:Thienamycins / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D013845:Thienamycins; D002939:Ciprofloxacin; D015378:Imipenem