title: An isolated pulmonary metastasis in prostate cancer.
abstract: A pulmonary metastasis of prostate cancer in the absence of osseous or lymph node metastases is an extremely rare finding. We report the case of a 49-year-old man with a history of stage T2CN0M0 prostate cancer who had undergone a radical perineal prostatectomy and laparoscopic lymph node dissection, pelvic radiotherapy, and hormonal manipulation. He developed a solitary pulmonary nodule with a negative bone scan and computed tomography of his chest, abdomen, and pelvis. As a result, he underwent an open biopsy and lobectomy. The final pathology of the specimen was consistent with a metastatic lesion that stained positive for prostate-specific antigen. We present this unusual case and a review of the small number of similar cases that have been reported.
authors.affiliation: Department of Urology, William Beaumont Army Medical Center, El Paso, TX 79916, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Hofland
authors.forename: M D
authors.initials: MD
authors.lastname: Bagg
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D001706:Biopsy; D001932:Brain Neoplasms / Q000175:diagnosis / Q000556:secondary*; D003131:Combined Modality Therapy; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011013:Pneumonectomy; D017430:Prostate-Specific Antigen / Q000032:analysis / Q000097:blood; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000097:blood / Q000473:pathology* / Q000628:therapy
chemical_list: D017430:Prostate-Specific Antigen