title: Repair of interrupted aortic arch: results after more than 20 years.
abstract: BACKGROUND
  This study focused on the influence of concomitant anomalies, the individual surgical approach, and the probability for reinterventions.
  
  
  METHODS
  Between 1975 and 1999, 94 patients with interrupted aortic arch were evaluated for short- and long-term results after surgical treatment.
  
  
  RESULTS
  Interrupted aortic arch was associated mainly with a ventricular septal defect (85%) and left ventricular outflow tract obstruction (LVOTO, 13%). Mean follow-up was 6.7 years (median 6.9 years, 628.4 patient years). A single-stage operation was performed in 76 cases. Early mortality for two-stage procedures was 37% and late mortality was 26%, compared with single-stage procedures, with an early mortality of 12% and a late mortality of 20%, respectively. Early mortality in patients with additional LVOTO was 42% and late mortality was 50%. Freedom from reoperation at 5 years was 62%, and at 10 years was 49%. Reinterventions were performed mainly for residual arch stenosis, also with bronchus or tracheal compression, or LVOTO.
  
  
  CONCLUSIONS
  Arch continuity and repair of associated anomalies can be achieved with an acceptable overall risk in this often complex entity. Associated anomalies play an important role in the outcome. Single-stage repair with primary anastomosis of the arch should be the surgical goal. The long-term probability for reoperation is high.
authors.affiliation: Department of Cardiac and Vascular Surgery, German Heart Center, Technical University of Munich. schreiber@dhm.mhn.de
authors.forename: C
authors.initials: C
authors.lastname: Schreiber
authors.forename: A
authors.initials: A
authors.lastname: Eicken
authors.forename: M
authors.initials: M
authors.lastname: Vogt
authors.forename: T
authors.initials: T
authors.lastname: Günther
authors.forename: M
authors.initials: M
authors.lastname: Wottke
authors.forename: M
authors.initials: M
authors.lastname: Thielmann
authors.forename: S U
authors.initials: SU
authors.lastname: Paek
authors.forename: H
authors.initials: H
authors.lastname: Meisner
authors.forename: J
authors.initials: J
authors.lastname: Hess
authors.forename: R
authors.initials: R
authors.lastname: Lange
mesh_terms: D000293:Adolescent; D000328:Adult; D001017:Aortic Coarctation / Q000401:mortality / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000401:mortality / Q000601:surgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011183:Postoperative Complications / Q000209:etiology* / Q000401:mortality / Q000601:surgery; D012086:Reoperation; D012307:Risk Factors; D015996:Survival Rate; D014694:Ventricular Outflow Obstruction / Q000401:mortality / Q000601:surgery