title: Diffusion-weighted MR imaging in a case of mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes.
abstract: In a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS), both T2- and diffusion-weighted MR imaging revealed lesions as hyperintense areas in the occipital lobes early after strokelike episodes. In these lesions, no significant reduction in apparent diffusion coefficient was noted. Apparent diffusion coefficient mapping may help to differentiate strokelike episodes in MELAS from acute ischemic stroke. The strokelike episodes may be related to vasogenic edema and hyperperfusion, which were suggested by our single-photon emission CT and MR imaging studies.
authors.affiliation: Department of Medicine, National Cardiovascular Center, Suita, Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yonemura
authors.forename: Y
authors.initials: Y
authors.lastname: Hasegawa
authors.forename: K
authors.initials: K
authors.lastname: Kimura
authors.forename: K
authors.initials: K
authors.lastname: Minematsu
authors.forename: T
authors.initials: T
authors.lastname: Yamaguchi
mesh_terms: D000328:Adult; D006801:Humans; D017241:MELAS Syndrome / Q000150:complications*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D020521:Stroke / Q000175:diagnosis* / Q000209:etiology*