title: Biomesogenic matrix systems.
abstract: The bifunctionally reactive nucleoside and distant nucleoside analogs adenosine (Ado), S-[(adenine-9-yl)methoxyethyl]-L-cysteine (Na-salt) (cysA) and 9-vinyladenine (vA) in aqueous solutions assemble on complementary polyuridylic acid templates to form complex lyomesophases. The systems are investigated by polarizing microscopy, differential scanning calorimetry (DSC) and 1H- and 31P-nmr spectroscopies, assisted by molecular modeling studies. The results indicate the importance of biomesogenic (pre)ordering in nucleic acid native and artificial matrix reactions.
authors.affiliation: Martin Luther University Halle-Wittenberg, Institute of Biochemistry, Saale, Germany. meister@biochemtech.uni-halle.de
authors.forename: W V
authors.initials: WV
authors.lastname: Meister
authors.forename: S
authors.initials: S
authors.lastname: Lindau
authors.forename: A L
authors.initials: AL
authors.lastname: Hauser
authors.forename: C
authors.initials: C
authors.lastname: Bohley
authors.forename: U
authors.initials: U
authors.lastname: Gromann
authors.forename: S
authors.initials: S
authors.lastname: Naumann
authors.forename: M
authors.initials: M
authors.lastname: Madre
authors.forename: L
authors.initials: L
authors.lastname: Kovalenko
authors.forename: G
authors.initials: G
authors.lastname: Bischoff
authors.forename: R
authors.initials: R
authors.lastname: Zhuk
authors.forename: S
authors.initials: S
authors.lastname: Hoffmann
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives / Q000737:chemistry; D000241:Adenosine / Q000737:chemistry; D002152:Calorimetry, Differential Scanning; D046911:Macromolecular Substances; D009682:Magnetic Resonance Spectroscopy; D008859:Microscopy, Polarization; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D011072:Poly U / Q000737:chemistry; D011131:Polyribonucleotides / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D046911:Macromolecular Substances; D011131:Polyribonucleotides; D011072:Poly U; D000225:Adenine; D000241:Adenosine