[New bioadhesive ADAL-1: determination of its tensile strength to join muscle tissue to sclera].
OBJECTIVE
To quantify tensile force to separate the adhesive joint between muscle and sclera obtained by the ADAL-1 adhesive.


METHODS
Strabismus surgery including over the Superior Recti was performed. 4 different groups (5 eyes each) were included in this study on New Zealand albino rabbits and lamb eyes. We used Dexon 6/0 suture as control group. We evaluated the tensile force by means of a dynamometer in two periods of time. First, we evaluated just after the adhesion (groups I and II), and after 7 days of the adhesion (groups III and IV).


RESULTS
By statistical supported methods SPSS 6.0. The tensile force in group I was: X=1.23 +/- 0.17 Newtons. In group II was X=0.793+/-0.02. In group III the tensile force was: X=1.01+/-0.17 and in group IV was X=0.89+/-0.09 Newtons. There was a significant difference between the two groups: suture and ADAL-l, just immediately after the adhesion. (P=0.004). There was no significant difference between the suture and ADAL-1 adhesive group, one week after the adhesion.


CONCLUSIONS
The joint between sclera and muscle by the ADAL-1 adhesive is as resistant as Dexon 6/0 suture group to the traction force one week after surgery.
Mulet Homs ME
Universidad Miguel Hernández, División de Oftalmología, Alicante, España.
Alió Y Sanz JL
Sakla
H F
HF
Mahiques Bujanda MM
Martín Martínez JM
D000818:Animals; D004353:Drug Evaluation, Preclinical; D009801:Oculomotor Muscles; D011817:Rabbits; D012590:Sclera; D012756:Sheep; D012984:Software; D013536:Suture Techniques; D013718:Tensile Strength; D014014:Tissue Adhesives
D014014:Tissue Adhesives