Cellular delivery of trophic factors for the treatment of Huntington's disease: is neuroprotection possible?
Kordower
J H
JH
Research Center for Brain Repair and Department of Neurological Sciences, Rush Presbyterian Medical Center, 2242 West Harrison Street, Chicago, IL 60612, USA. jkordowe@rush.rpslmc.edu
Isacson
O
O
Leventhal
L
L
Emerich
D F
DF
D000818:Animals; D016380:Brain Tissue Transplantation; D064987:Cell- and Tissue-Based Therapy; D002478:Cells, Cultured / Q000637:transplantation; D020934:Ciliary Neurotrophic Factor / Q000494:pharmacology / Q000627:therapeutic use; D004195:Disease Models, Animal; D016503:Drug Delivery Systems / Q000379:methods*; D006085:Graft Survival / Q000502:physiology; D006801:Humans; D006816:Huntington Disease / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D017072:Neostriatum / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D020932:Nerve Growth Factor / Q000494:pharmacology / Q000627:therapeutic use; D009414:Nerve Growth Factors / Q000627:therapeutic use*; D018696:Neuroprotective Agents / Q000627:therapeutic use*
D020934:Ciliary Neurotrophic Factor; D009414:Nerve Growth Factors; D018696:Neuroprotective Agents; D020932:Nerve Growth Factor