Erosive and non-erosive hand osteoarthritis. Use and limitations of two scoring systems.
OBJECTIVE
To assess the evolution and progression of osteoarthritis (OA) in the finger joints using anatomical changes on standard radiographs.


METHODS
Data obtained from 85 patients enrolled in a prospective study were used to evaluate systems to score the morbidity and the progression of the disease over 3 years. Posteroanterior (PA) radiographs of the metacarpophalangeal (MCP) and interphalangeal (IP) joints were obtained at entry and after 3 years. Assessment of the progression of OA over time is based on: (1) the increase in incidence of OA in previously normal joints during the study period, (2) the changes in the OA-associated features (osteophyte growth, loss of joint space, subchondral cysts or sclerosis) in the pathological finger joints (anatomical lesion progression score system), and (3) the recognition of consecutive anatomical phases in the course of 'erosive' OA (anatomical phase progression score system).


RESULTS
Almost 80% of the distal IP and 50% of the proximal IP were affected at study entry. In approximately 40% of the patients, the classical picture of OA of the IP joints was complicated by manifest erosive changes, which were followed by a repair phenomenon in the 'eroded' finger joints. MCP were less affected and showed the non-erosive picture of OA. Numbers of affected DIP, PIP and MCP joints per patient at entry did not differ from those after 3 years of follow-up. Two systems to score the progression of OA (anatomical lesion and anatomical phase progression score system) showed definite progression within 3 years of follow-up, especially in the IP joints. Since changes in both non-erosive and erosive joints were recorded by the anatomical lesion progression system, it was found much more sensitive to change than the anatomical phase progression system which principally recorded the progression through the destructive phases of erosive OA. The results of both progression score systems correlated well.


CONCLUSIONS
Conventional radiographs can be used to assess the morbidity and progression of hand OA. The existence of non-erosive and erosive forms of OA of the finger joints necessitates the use of two scoring systems: the anatomical lesion progression score system and the anatomical phase progression score system.
Verbruggen
G
G
Department of Rheumatology, Ghent University Hospital, University of Ghent, Belgium. gust.verbruggen@rug.ac.be
Veys
E M
EM
D000328:Adult; D000368:Aged; D018450:Disease Progression; D006227:Hand Deformities, Acquired / Q000000981:diagnostic imaging*; D006801:Humans; D008875:Middle Aged; D015588:Observer Variation; D010003:Osteoarthritis / Q000000981:diagnostic imaging*; D011859:Radiography; D012720:Severity of Illness Index