title: Gamma knife radiosurgery for torsion spasm. Report of two cases.
abstract: The authors report on two patients who underwent radiosurgery for torsion spasm and evaluate the efficiency of gamma knife radiosurgery (GKS) as an alternative treatment. The first patient was a 33-year-old woman with severe right-sided lower-limb torsion dystonia. The second patient was a 20-year-old man with right-sided upper-limb torsion dystonia. The target was located at the anterior portion of the ventrolateral nucleus. The maximum doses were 150 Gy and 145 Gy, respectively. Double isocenters with a 4-mm collimator were used. Follow up lasted for 18 months and 8 months, respectively. Both patients had excellent clinical improvement 2 to 3 months after GKS, respectively. The authors believe that GKS may be a safe and efficient treatment for torsion spasm.
authors.affiliation: Department of Neurosurgery, Shanghai Gamma Knife Hospital and Shanghai Huashan Hospital, Shanghai Medical University, People's Republic of China. nanzhang@sina.com
authors.forename: L
authors.initials: L
authors.lastname: Pan
authors.forename: N
authors.initials: N
authors.lastname: Zhang
authors.forename: J Z
authors.initials: JZ
authors.lastname: Dai
authors.forename: E M
authors.initials: EM
authors.lastname: Wang
mesh_terms: D000328:Adult; D004422:Dystonia Musculorum Deformans / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016634:Radiosurgery; D016896:Treatment Outcome; D020651:Ventral Thalamic Nuclei / Q000601:surgery*