title: Fels-Rand: an Xlisp-Stat program for the comparative analysis of data under phylogenetic uncertainty.
abstract: BACKGROUND
  Currently available programs for the comparative analysis of phylogenetic data do not perform optimally when the phylogeny is not completely specified (i.e. the phylogeny contains polytomies). Recent literature suggests that a better way to analyse the data would be to create random trees from the known phylogeny that are fully-resolved but consistent with the known tree. A computer program is presented, Fels-Rand, that performs such analyses. A randomisation procedure is used to generate trees that are fully resolved but whose structure is consistent with the original tree. Statistics are then calculated on a large number of these randomly-generated trees. Fels-Rand uses the object-oriented features of Xlisp-Stat to manipulate internal tree representations. Xlisp-Stat's dynamic graphing features are used to provide heuristic tools to aid in analysis, particularly outlier analysis. The usefulness of Xlisp-Stat as a system for phylogenetic computation is discussed.
  
  
  BACKGROUND
  Available from the author or at http://www.uq.edu.au/~ansblomb/Fels-Rand.sit.hqx. Xlisp-Stat is available from http://stat.umn.edu/~luke/xls/xlsinfo/xlsinfo.html.
  
  
  BACKGROUND
  s.blomberg@abdn.ac.uk
authors.affiliation: Department of Zoology, University of Aberdeen, Aberdeen AB24 2TZ, Scotland, UK. s.blomberg@abdn.ac.uk
authors.forename: S
authors.initials: S
authors.lastname: Blomberg
mesh_terms: D000465:Algorithms; D019295:Computational Biology; D003196:Computer Graphics; D003627:Data Interpretation, Statistical; D005821:Genetic Techniques; D010802:Phylogeny; D011897:Random Allocation; D012984:Software