Benign conditions associated with raised serum CA-125 concentration.
A retrospective audit carried out in the Department of Clinical Biochemistry, covering a period of 42 months, showed 19 benign conditions, that gave rise to elevated serum CA-125 concentrations. These included six patients with non-malignant gynaecological disease, six patients with abdominal disorders, and seven patients with lung disease. These observations confirm that false-positive elevations can occur and that care must be taken before attributing an elevated serum CA-125 as an indicator of ovarian malignancy.
Buamah
P
P
Department of Clinical Biochemistry, Queen Elizabeth the Queen Mother Hospital, Kent, England.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018394:CA-125 Antigen / Q000097:blood*; D005260:Female; D005831:Genital Diseases, Female / Q000276:immunology*; D006801:Humans; D008171:Lung Diseases / Q000276:immunology*; D008485:Medical Audit; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000276:immunology*; D012189:Retrospective Studies
D018394:CA-125 Antigen