Pentavalent technetium-99m DMSA uptake in pseudofractures of osteomalacia.
Tc-99m MDP and Tc-99m (V) DMSA images are described from a 49-year-old woman with chronic renal insufficiency complicated by osteomalacia. Clinical, biochemical, and radiologic bone profiles were compatible with osteomalacia. Osteomalacia is a condition associated with disorders in which mineralization of the organic matrix is defective. All bone lesions visualized with Tc-99m MDP also showed increased uptake of Tc-99m (V) DMSA. Tc-99m (V) DMSA accumulation has been reported in many malignant and some benign conditions. Pseudofractures in osteomalacia could be included in the spectrum of benign lesions that accumulate Tc-99m (V) DMSA.
Sahin
M
M
Department of Nuclear Medicine, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey. murathans@superonline.com
Basoglu
T
T
Albayrak
S
S
Canbaz
F
F
Yapici
O
O
D001842:Bone and Bones / Q000000981:diagnostic imaging*; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000150:complications / Q000000981:diagnostic imaging; D005260:Female; D050723:Fractures, Bone / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D008875:Middle Aged; D010018:Osteomalacia / Q000150:complications / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D019783:Technetium Tc 99m Dimercaptosuccinic Acid
D019275:Radiopharmaceuticals; D019783:Technetium Tc 99m Dimercaptosuccinic Acid