title: Changes in vocal intensity in Parkinson's disease following pallidotomy surgery.
abstract: The present study was designed to examine changes in vocal intensity following unilateral posteroventral pallidotomy (PVP) in a large sample of speakers with Parkinson's disease (PD) that exhibited a range of hypokinetic dysarthria. Twenty-five persons with PD were recorded using a variety of speech tasks, once prior to and once following PVP. The pre-PVP vocal SPL was subtracted from the post-PVP vocal SPL to derive a relative change in vocal SPL. Mildly dysarthric participants had significantly greater relative increases in vocal SPL following PVP than either moderately or severely dysarthric participants who had reduced vocal SPL following PVP. If future results follow those observed in the present data, mildly dysarthric Parkinson's patients may benefit most from unilateral PVP perhaps due to less overall destruction of the basal ganglia sensorimotor control circuits involved in oral facial functions, thus increasing the chances to observe improvements postsurgery.
authors.affiliation: Department of Communication Sciences and Disorders, University of Florida, Gainesville 32611-7420, USA. schulz@csd.ufl.edu
authors.forename: G M
authors.initials: GM
authors.lastname: Schulz
authors.forename: M
authors.initials: M
authors.lastname: Greer
authors.forename: W
authors.initials: W
authors.lastname: Friedman
mesh_terms: D000368:Aged; D004401:Dysarthria / Q000209:etiology; D005260:Female; D005917:Globus Pallidus / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000503:physiopathology* / Q000601:surgery*; D010700:Phonetics; D011184:Postoperative Period; D011312:Pressure; D014833:Voice Quality