Eosinophilic pleocytosis and myelitis related to Toxocara canis infection.
Toxocara canis causes the visceral larva migrans syndrome in which central nervous involvement is rare. We report the case of a 40-year-old woman presenting with a subacute weakness of the right leg and dysaesthesiae in the right Th8-Th10 dermatomas. Spinal magnetic resonance imaging examination showed abnormal hyperintensity within the spinal cord. Cerebrospinal fluid analysis revealed eosinophilic pleocytosis. Antibody titres to Toxocara canis were higher in the cerebrospinal fluid than in the serum. Treatment using mebendazole led to a complete clinical recovery, normalization of cerebrospinal fluid parameters and improvement in spinal magnetic resonance imaging abnormalities.
Goffette
S
S
Service de Neurologie, Cliniques Universitaires Saint-Luc, 1200 Brussels, Belgium.
Jeanjean
A P
AP
Duprez
T P
TP
Bigaignon
G
G
Sindic
C J
CJ
D000328:Adult; D000818:Animals; D004804:Eosinophils; D005260:Female; D006801:Humans; D006941:Hyperesthesia; D006987:Hypesthesia; D007964:Leukocytosis / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D009187:Myelitis / Q000209:etiology*; D013116:Spinal Cord / Q000473:pathology; D017166:Toxocara canis; D014120:Toxocariasis / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology