title: Production of terbium-152 by heavy ion reactions and proton induced spallation.
abstract: Terbium-152 (Tb-152) is of potential value as a radiotracer for radiolanthanides in positron emission tomography. We report the production of Tb-152 by heavy ion reactions at the ANU Tandem accelerator, and by the spallation method at the CERN proton accelerator using the on-line ISOLDE separator, obtaining microcurie and millicurie yields, respectively. After purification, a phantom image in PET is obtained which shows the feasibility of using Tb-152 for monitoring the kinetics of Tb-149 and other radiolanthanides. However, the current availability of this radioisotope will be restricted to major nuclear physics research centres.
authors.affiliation: Centre for Experimental Radiation Oncology, St George Cancer Care Centre, Kogarah, NSW, Australia. b.allen@unsw.edu.au
authors.forename: B J
authors.initials: BJ
authors.lastname: Allen
authors.forename: G
authors.initials: G
authors.lastname: Goozee
authors.forename: S
authors.initials: S
authors.lastname: Sarkar
authors.forename: G
authors.initials: G
authors.lastname: Beyer
authors.forename: C
authors.initials: C
authors.lastname: Morel
authors.forename: A P
authors.initials: AP
authors.lastname: Byrne
mesh_terms: D007700:Kinetics; D008674:Metals, Rare Earth; D010315:Particle Accelerators; D011522:Protons; D011868:Radioisotopes; D019275:Radiopharmaceuticals; D013725:Terbium; D013910:Thorium; D014055:Tomography, Emission-Computed
chemical_list: D008674:Metals, Rare Earth; D011522:Protons; D011868:Radioisotopes; D019275:Radiopharmaceuticals; D013725:Terbium; D013910:Thorium