title: Molluscicidal saponins from Phytolacca icosandra.
abstract: Five monodesmosidic serjanic acid saponins and a monodesmosidic spergulagenic acid saponin were isolated from an aqueous extract of the berries of Phytolacca icosandra. A methanol extract of the berries furnished three bidesmosidic serjanic acid glycosides. Their structures were established by spectroscopic (ES-MS, 1H NMR, COSY, HSQC, HMBC, 13C NMR) and chemical methods. The molluscicidal, spermicidal and haemolytic properties of the saponins were investigated.
authors.affiliation: Institut de Pharmacognosie et Phytochimie, Université de Lausanne, Switzerland.
authors.forename: V
authors.initials: V
authors.lastname: Treyvaud
authors.forename: A
authors.initials: A
authors.lastname: Marston
authors.forename: W
authors.initials: W
authors.lastname: Dyatmiko
authors.forename: K
authors.initials: K
authors.lastname: Hostettmann
mesh_terms: D000818:Animals; D002417:Cattle; D005638:Fruit / Q000737:chemistry; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry*; D008297:Male; D008974:Mollusca / Q000187:drug effects; D008975:Molluscacides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D013089:Spermatocidal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013094:Spermatozoa / Q000187:drug effects
chemical_list: D008975:Molluscacides; D012503:Saponins; D013089:Spermatocidal Agents