Choice of antibiotic and risk of colonization with vancomycin-resistant Enterococcus among patients admitted for treatment of community-acquired pneumonia.
A time-series prospective study of patients admitted to the hospital for treatment of community-acquired pneumonia was undertaken to determine vancomycin-resistant enterococcal perianal colonization rates among patients who received ceftriaxone with or without erythromycin versus those who received levofloxacin. A colonization rate of 16% (8/51) was found in the ceftriaxone-erythromycin group versus 0% (0/52) in the levofloxacin group .
Manzella
J
J
Department of Medicine, York Hospital, Pennsylvania 17405, USA.
Benenson
R
R
Pellerin
G
G
Kellogg
J
J
Bell
T
T
Robertson
M
M
Pope
D
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002443:Ceftriaxone / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D017714:Community-Acquired Infections; D004359:Drug Therapy, Combination; D016983:Enterococcus / Q000187:drug effects* / Q000472:pathogenicity; D004917:Erythromycin / Q000627:therapeutic use; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy*; D006801:Humans; D064704:Levofloxacin; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000627:therapeutic use; D018410:Pneumonia, Bacterial; D011446:Prospective Studies; D012307:Risk Factors; D020713:Vancomycin Resistance
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D002511:Cephalosporins; D004917:Erythromycin; D064704:Levofloxacin; D002443:Ceftriaxone; D015242:Ofloxacin