Pseudoadenomatous hyperplasia of the conjunctiva.
OBJECTIVE
To describe the clinical and pathologic features of three patients with pseudoadenomatous hyperplasia of the conjunctiva.


METHODS
Observational case series with clinicopathologic correlation.


METHODS
Case reports and clinical histories and examination of three biopsy specimens.


RESULTS
Pseudoglandular hyperplasia of the conjunctiva was associated with chronic inflammation, including eosinophils, in two patients, and squamous epithelial hyperplasia in a third. The pseudoglands are lined by varying proportions of squamous epithelium and goblet cells.


CONCLUSIONS
Pseudoglandular hyperplasia of the conjunctiva can mimic a well-differentiated mucoepidermoid carcinoma. Awareness of this entity may help to prevent misdiagnosis and unnecessary surgery.
Margo
C E
CE
Department of Ophthalmology, Watson Clinic, Lakeland, Florida, USA.
Grossniklaus
H E
HE
D000287:Administration, Topical; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D018277:Carcinoma, Mucoepidermoid / Q000473:pathology; D003228:Conjunctiva / Q000187:drug effects / Q000473:pathology*; D003907:Dexamethasone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004804:Eosinophils / Q000473:pathology; D004847:Epithelial Cells / Q000187:drug effects / Q000473:pathology; D005938:Glucocorticoids; D006801:Humans; D006965:Hyperplasia / Q000188:drug therapy / Q000473:pathology; D008297:Male
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D003907:Dexamethasone