Comparative study of the lamina cribrosa and the pial septa in the vertebrate optic nerve and their relationship to the myelinated axons.
The optic nerve contains the connective tissues, i.e. the lamina cribrosa and pial septa. This report presents a histological comparison of the lamina cribrosa and pial septa in the five classes (mammals, birds, reptiles, amphibians and teleosts) of vertebrates. Furthermore, the distribution of myelinated fibers was observed from the optic nerve through the retina in the same animals. The lamina cribrosa is found in mammals except for mice, and in birds. Structural complexity of the lamina was different in animals but generally dependent of the optic nerve thickness. The pial septa were present in the optic nerve proper of the mammals except for the mice, in birds and in a part of teleosts. Fasciculation of the optic nerve by the pial septa tended to be more prominent as the optic nerve become thicker. The optic nerve consisted of largely myelinated fibers in vertebrates. The retina contained some myelinated fibers in submammals but was thoroughly devoid of myelinated fibers in mammals. The borderline between myelinated and unmyelinated portions in the optic nerve of different species did not related to the lamina cribrosa. Amphibians had exceptionally only a few myelinated fibers in the optic nerve and no myelinated fibers in the retina.
Fujita
Y
Y
Department of Veterinary Anatomy, Faculty of Agriculture, Tottori University, Japan.
Imagawa
T
T
Uehara
M
M
D000663:Amphibians / Q000033:anatomy & histology / Q000502:physiology; D000818:Animals; D001369:Axons / Q000502:physiology / Q000648:ultrastructure*; D001717:Birds / Q000033:anatomy & histology / Q000502:physiology; D003238:Connective Tissue / Q000502:physiology / Q000648:ultrastructure*; D005399:Fishes / Q000033:anatomy & histology / Q000502:physiology; D005901:Glaucoma / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D008322:Mammals / Q000033:anatomy & histology / Q000502:physiology; D009413:Nerve Fibers, Myelinated / Q000502:physiology / Q000648:ultrastructure*; D009898:Optic Disk / Q000502:physiology / Q000648:ultrastructure; D009900:Optic Nerve / Q000502:physiology / Q000648:ultrastructure*; D010841:Pia Mater / Q000502:physiology / Q000648:ultrastructure*; D012104:Reptiles / Q000033:anatomy & histology / Q000502:physiology; D012165:Retinal Ganglion Cells / Q000502:physiology / Q000648:ultrastructure; D014714:Vertebrates / Q000033:anatomy & histology* / Q000502:physiology