title: Freezing immature oocytes.
abstract: The establishment of a long-term preservation system for mammalian oocytes is important for the development of both biological and medical sciences. A number of efforts have been made to develop this system. In human reproductive medicine, the development of an oocyte cryopreservation system can improve the efficacy of the current assisted reproductive technology (ART) for infertile patients with severe reproductive disorders. In this article, the technical development of cryopreservation programs for human oocytes and its biological background were reviewed. Clinical outcome after the use of this technology was further introduced.
authors.affiliation: College of Medicine, Pochon CHA University and Infertility Medical Center of CHA General Hospital, South Korea.
authors.forename: K Y
authors.initials: KY
authors.lastname: Cha
authors.forename: H M
authors.initials: HM
authors.lastname: Chung
authors.forename: J M
authors.initials: JM
authors.lastname: Lim
authors.forename: J J
authors.initials: JJ
authors.lastname: Ko
authors.forename: S Y
authors.initials: SY
authors.lastname: Han
authors.forename: D H
authors.initials: DH
authors.lastname: Choi
authors.forename: T K
authors.initials: TK
authors.lastname: Yoon
mesh_terms: D018929:Cell Culture Techniques / Q000379:methods; D015925:Cryopreservation / Q000266:history / Q000379:methods* / Q000592:standards; D005060:Europe; D005260:Female; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007247:Infertility, Female; D009865:Oocytes / Q000166:cytology*; D011247:Pregnancy; D012099:Reproductive Techniques