Two new alkaloids from cigarette smoke condensate.
Chemical constituents of MeOH extracts of cigarette smoke were studied. Two new alkaloids, named cigatin A (1), 2-(Pyridine-3-yloxy)-benzene-1',4'-diol and B (2), 2-(4-Methyl-pyridin-3-yloxy)-benzene-1',4'-diol, were isolated from a mainstream condensate of cigarette together with seven known alkaloids. Their structures were determined on the basis of spectral data and chemical methods.
Yun
Y S
YS
National Institute of Health Sciences, Tokyo, Japan.
Sugimoto
N
N
Sekita
S
S
Maitani
T
T
Yamada
T
T
Satake
M
M
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification; D006873:Hydroquinones / Q000737:chemistry / Q000302:isolation & purification*; D011725:Pyridines / Q000737:chemistry / Q000302:isolation & purification*; D013638:Tars / Q000737:chemistry*
D000470:Alkaloids; D006873:Hydroquinones; D011725:Pyridines; D013638:Tars; C423470:cigatin A; C423471:cigatin B; C024746:tobacco tar