Pelvic cancer pain.
Pelvic cancer causes several types of pain, i.e., visceral, neuropathic, and somatic pain. Somatic pain is due to stimulation of nociceptors in the integument and supporting structures, namely, striated muscles, joints, periosteum, bones, and nerve trunks by direct extension through fascial planes and their lymphatic supply. In 60% of patients with malignant disease of soft tissues, nerve trunk, and sacral invasion from carcinoma of the cervix, uterus, vagina, colon, rectum, and other tissues in women, and from penile, prostate, and colorectal carcinoma and sarcoma in men, they have neuropathic pain. The infiltration of the perineal nerves results in lumbosacral plexopathies and complete destruction of the nerve, including perineural lymphatic invasions producing symptomatic sensory loss, causalgia, and deafferentation. Visceral pain is the result of spasms of smooth muscles of hallow viscus; distortion of capsule of solid organs; inflammation; chemical irritation; traction or twisting of mesentery; and ischemia, or necrosis, and encroachment of pelvis and presacral tumors. Pain of these types is managed by different modalities depending on the age of the patient, the expected life expectancy, availability of invasive and non-invasive pain control modalities, and the resources of the patient, community, and health care agencies. Patients with pelvic cancer can live with less pain due to better pain-control modalities that are available today with the help of dedicated and caring algologists.
Rigor
B M
BM
Department of Anesthesiology, School of Medicine, University of Louisville, Louisville, Kentucky, USA.
D000344:Afferent Pathways / Q000502:physiology; D016058:Analgesia, Patient-Controlled; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003131:Combined Modality Therapy; D004333:Drug Administration Routes; D005260:Female; D006699:Home Care Services; D006801:Humans; D007001:Hypogastric Plexus / Q000503:physiopathology; D008297:Male; D009407:Nerve Block; D010147:Pain Measurement / Q000379:methods*; D010386:Pelvic Neoplasms / Q000188:drug therapy / Q000503:physiopathology* / Q000523:psychology; D017699:Pelvic Pain / Q000145:classification* / Q000209:etiology / Q000523:psychology / Q000628:therapy; D013116:Spinal Cord / Q000502:physiology
D000701:Analgesics, Opioid; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents