title: The challenge of assessing children's residential exposure to pesticides.
abstract: In implementing the Food Quality Protection Act (FQPA) the U.S. Environmental Protection Agency (USEPA) has adopted a policy that the exposure factors and models used to assess and predict exposure to pesticides should generally be conservative. Some elements of exposure assessments for FQPA are screening level--they are both uncertain and conservative. If more realistic assessments are to be conducted, then research is required to reduce uncertainty associated with the factors and models used in the exposure assessments. To develop the strategy for conducting this research, critical exposure pathways and factors were identified, and the quality and quantity of data associated with default assumptions for exposure factors were evaluated. Then, based on our current understanding of the pathways that are potentially most important and most uncertain, significant research requirements were identified and prioritized to improve the data available and assumptions used to assess children's aggregate exposure to pesticides. Based on the results of these efforts, four priority research areas were identified: (1) pesticide use patterns in microenvironments where children spend time, (2) temporal and spatial distribution of pesticides following application in a residential setting, (3) dermal and nondietary ingestion exposure assessment methods and exposure factors, (4) dietary exposure assessment methods and exposure factors for infants and young children. The National Exposure Research Laboratory (NERL) research strategy in support of FQPA is designed to address these priority research needs.
authors.affiliation: National Exposure Research Laboratory, U.S. EPA, Research Triangle Park, North Carolina 27711, USA. hubal.elaine@epamail.epa.gov
authors.forename: E A
authors.initials: EA
authors.lastname: Hubal
authors.forename: L S
authors.initials: LS
authors.lastname: Sheldon
authors.forename: M J
authors.initials: MJ
authors.lastname: Zufall
authors.forename: J M
authors.initials: JM
authors.lastname: Burke
authors.forename: K W
authors.initials: KW
authors.lastname: Thomas
mesh_terms: D000279:Administration, Cutaneous; D000293:Adolescent; D002648:Child; D002669:Child Welfare; D002675:Child, Preschool; D004032:Diet; D004781:Environmental Exposure; D005506:Food Contamination; D006798:Housing; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008962:Models, Theoretical; D010575:Pesticides / Q000009:adverse effects* / Q000032:analysis; D018570:Risk Assessment; D013997:Time Factors
chemical_list: D010575:Pesticides