Association between C-reactive protein, anti-Chlamydia pneumoniae antibodies, and vascular function in healthy adults.
Abnormalities of vascular function occur in patients with risk factors for atherosclerosis before the development of obstructive disease. Our pilot data suggest that elevated serum markers of infection and/or inflammation are associated with functional abnormalities of the vasculature in subjects at otherwise low risk for atherosclerosis.
Sharma
N
N
University of Texas Southwestern Medical School, Dallas 75390-9034, USA.
Rutherford
J D
JD
Grayston
J T
JT
King
L P
LP
Jialal
I
I
Andrews
T C
TC
D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D000907:Antibodies, Bacterial / Q000097:blood*; D001161:Arteriosclerosis / Q000209:etiology; D002097:C-Reactive Protein / Q000378:metabolism*; D016993:Chlamydophila pneumoniae / Q000276:immunology*; D004730:Endothelium, Vascular / Q000502:physiology*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin; D010865:Pilot Projects; D014664:Vasodilation / Q000502:physiology*; D014665:Vasodilator Agents
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D014665:Vasodilator Agents; D002097:C-Reactive Protein; D005996:Nitroglycerin