title: Synthesis of a highly hydrophobic dimeric Lewis X containing glycolipid: a model for the study of homotypic carbohydrate--carbohydrate interaction.
abstract: This paper describes the synthesis of an octasaccharidic glycolipid 1 based on a stereo- and regioselective glycosylation between a Lewis X trisaccharidic donor and a pentasaccharidic acceptor. A highly hydrophobic lipid moiety of a new type was selected, making the compound 1 a good candidate for the study of the interaction of Lewis X functionalised vesicles.
authors.affiliation: Ecole Normale Supérieure, Département de Chimie, CNRS UMR 8642, Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Bregant
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: J M
authors.initials: JM
authors.lastname: Mallet
authors.forename: A
authors.initials: A
authors.lastname: Brodzki
authors.forename: P
authors.initials: P
authors.lastname: Sinaÿ
mesh_terms: D002240:Carbohydrate Sequence; D019281:Dimerization; D006017:Glycolipids / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism; D006031:Glycosylation; D006801:Humans; D016256:Lewis X Antigen / Q000737:chemistry* / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D008969:Molecular Sequence Data; D015394:Molecular Structure
chemical_list: D006017:Glycolipids; D016256:Lewis X Antigen