Microbial transformation of the eudesmane sesquiterpene plectranthone.
Microbial transformation studies of plectranthone (1) have revealed that it was metabolized by a number of microorganisms. Using a standard two-stage fermentation technique, Beauvaria bassiana (ATCC 7159) produced five metabolites, 2-6. These metabolites were characterized on the basis of spectral data.
Orabi
K Y
KY
Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. kyorabi@ksu.edu.sa
D001711:Biotransformation; D019684:Magnoliopsida / Q000378:metabolism*; D012717:Sesquiterpenes / Q000493:pharmacokinetics*; D013057:Spectrum Analysis
D012717:Sesquiterpenes; C421085:plectranthone