Recurrent myelinoclastic diffuse sclerosis: a case report of a child with Schilder's variant of multiple sclerosis.
Myelinoclastic diffuse sclerosis (MDS, Schilder's disease) is a rare CNS demyelinating disorder affecting mainly children and usually presenting as an intracranial mass lesion. We report the first case of recurrent intracranial MDS where the third episode of demyelination involved the cervical spinal cord. This may represent a subset of the disease, which should be considered as Schilder's variant (childhood form) of multiple sclerosis.
Fitzgerald
M J
MJ
Radiology Department, Royal Children's Hospital, Flemington Road, Parkville, Victoria 3052, Australia.
Coleman
L T
LT
D002648:Child; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000145:classification / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis; D012008:Recurrence; D014057:Tomography, X-Ray Computed