Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range.
Hirsh
J
J
Hamilton Civics Hospitals Research Centre, Ontario, Canada.
Dalen
J
J
Anderson
D R
DR
Poller
L
L
Bussey
H
H
Ansell
J
J
Deykin
D
D
D000284:Administration, Oral; D000925:Anticoagulants / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000517:prevention & control; D003374:Coumarins / Q000494:pharmacology / Q000627:therapeutic use; D004347:Drug Interactions; D005502:Food; D006350:Heart Valve Prosthesis; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy; D013923:Thromboembolism / Q000517:prevention & control; D020246:Venous Thrombosis / Q000517:prevention & control; D014859:Warfarin / Q000494:pharmacology / Q000627:therapeutic use
D000925:Anticoagulants; D003374:Coumarins; D014859:Warfarin; C030123:coumarin