Dentatovestibular projections in the rat.
The dentatovestibular connections were investigated using anterograde and retrograde tracing methods. All parts of the cerebellar nucleus lateralis (NL) or dentate nucleus sent fibers onto the ipsilateral vestibular nuclear complex. In spite of their apparently widespread area of termination, dentatovestibular fibers were distributed differentially, according to the subregion of the NL they arose from. Fibers from the main, magnocellular region and the dorsolateral hump (dlh) reached the four main vestibular nuclei, but preferentially the superior (SV) and inferior (IV) vestibular nuclei. The projections to the lateral and the medial vestibular nuclei, which were less abundant, essentially originated from neurons located in the dlh. Fibers arising from the parvocellular subregion of Flood and Jansen terminated within the SV and IV only. Some rare reciprocal vestibulodentate projections were observed. These observations suggest highly integrated activities of dentatovestibular connections related to postural, but also vestibulo-oculomotor functions.
Delfini
C
C
Laboratoire de Neuroanatomie Fonctionnelle des Systèmes Sensorimoteurs, EA3107, UP7, 2 Place Jussieu, Case 7077, 75251 Paris, France. delfini@ccr.jussieu.fr
Diagne
M
M
Angaut
P
P
Buisseret
P
P
Buisseret-Delmas
C
C
D000818:Animals; D001710:Biotin / Q000031:analogs & derivatives*; D002529:Cerebellar Nuclei / Q000033:anatomy & histology* / Q000166:cytology; D003911:Dextrans; D005456:Fluorescent Dyes; D006651:Histocytochemistry; D006735:Horseradish Peroxidase; D009412:Nerve Fibers / Q000502:physiology; D009434:Neural Pathways / Q000033:anatomy & histology / Q000166:cytology; D009474:Neurons / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D014726:Vestibular Nuclei / Q000033:anatomy & histology* / Q000166:cytology
D003911:Dextrans; D005456:Fluorescent Dyes; C076397:biotinylated dextran amine; D001710:Biotin; D006735:Horseradish Peroxidase