[Teratogenic and embryotoxic effects of caffeine: facts and hypotheses].
Caffeine is a widespread natural methylaxanthine which easily crosses the placenta. In studies on animals, high doses of caffeine are associated with an embryotoxic effect and an increase in congenital malformations. However, those date have not been fully confirmed in the human. The article presents the current knowledge about the prenatal toxicity of caffeine.
Burdan
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F
Pracowni Teratologii Doświadczalnej przy Katedrze i Zakładzie Anatomii Prawidłowej Człowieka AM w Lublinie.
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000818:Animals; D002110:Caffeine / Q000633:toxicity*; D005260:Female; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D013723:Teratogens / Q000633:toxicity*
D013723:Teratogens; D002110:Caffeine