title: [A study of measles encephalitis with focal changes on MRI, auditory agnosia and expressive aphasia].
abstract: Acute measles encephalitis is a typical parainfectious encephalitis in which the brain is diffusely affected clinically and neuropathologically. We present here a 5-year-old case of measles encephalitis with intractable seizures, bitemporal MRI abnormalities, and neurological sequelae of auditory agnosia and aphasia. Pathophysiology of the focal MRI lesions and of expressive aphasia due to auditory agnosia was discussed. We stressed that the status convulsions and its ischemic effect played an important role on the development of the focal lesions rather than focal encephalitis or ADEM. In the course of auditory agnosia and acquired aphasia, the patient transiently expressed some meaningful words. The significance of this episode was discussed based on the sequential changes of symptoms and neuroimaging findings.
authors.affiliation: Department of Pediatrics, St. Luke's International Hospital, Tokyo.
authors.forename: A
authors.initials: A
authors.lastname: Honda
authors.forename: R
authors.initials: R
authors.lastname: Shibata
authors.forename: Y
authors.initials: Y
authors.lastname: Anzai
authors.forename: I
authors.initials: I
authors.lastname: Kusakawa
authors.forename: T
authors.initials: T
authors.lastname: Ohya
mesh_terms: D000208:Acute Disease; D000377:Agnosia / Q000209:etiology*; D001039:Aphasia, Broca / Q000209:etiology*; D002648:Child; D018792:Encephalitis, Viral / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008457:Measles / Q000150:complications* / Q000473:pathology; D012640:Seizures / Q000209:etiology; D013702:Temporal Lobe / Q000098:blood supply / Q000473:pathology; D013997:Time Factors