title: Otitis externa sicca/fibrotising external otitis (FEO) as a complication of Sjögren's syndrome.
abstract: Sjögren's syndrome (SS) is a condition characterized by sicca symptoms and by autoimmune features. We describe two SS patients with otitis externa fibroticans/sicca. One of these 2 patients developed a lesion of the tympanic membrane making it necessary to perform a tympantomy and meatoplasty. Our findings suggest firstly that the epithelial cell-mediated secretion of lamellar bodies and the production of the permeability barrier are defective in SS. Secondly, local moisturing and/or topical corticosteroid treatment in SS patients with sicca symptoms in the auditory canal could help to avoid reconstructive surgical treatment.
authors.affiliation: Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland. YRJO.KONTTINEN@helsinki.fi
authors.forename: Y T
authors.initials: YT
authors.lastname: Konttinen
authors.forename: H
authors.initials: H
authors.lastname: Ramsay
authors.forename: J
authors.initials: J
authors.lastname: Hietanen
authors.forename: T
authors.initials: T
authors.lastname: Sorsa
authors.forename: D
authors.initials: D
authors.lastname: Nordstrom
mesh_terms: D003638:Deafness / Q000209:etiology; D004423:Ear / Q000293:injuries; D005260:Female; D006314:Hearing Loss, Conductive / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010032:Otitis Externa / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D012859:Sjogren's Syndrome / Q000150:complications*; D014432:Tympanic Membrane / Q000473:pathology / Q000601:surgery; D014947:Wounds and Injuries / Q000150:complications