Effect of ascorbate and alpha-tocopherol on resistance of beta-carotene to oxidation.
The efficiency of ascorbate and alpha-tocopherol as stabilizers of beta-carotene, which is widely used in complex therapy and prevention of some diseases accompanied by oxidative stress, was studied. The latency of induced beta-carotene oxidation linearly depends on ascorbate concentration, while steady-state rate nonlinearly depends on the concentration of alpha-tocopherol, which attests to involvement of antioxidants in various stages of chain oxidation of beta-carotene.
Kozachenko
A I
AI
Laboratory of Physical and Chemical Basis of Cell Metabolsim Control, NM Emanuel' Institute of Biochemical Physics, Russian Academy of Sciences, Moscow. chembio@glasnet.ru
Gurevich
S M
SM
Nagler
L G
LG
D001205:Ascorbic Acid / Q000737:chemistry*; D007700:Kinetics; D010084:Oxidation-Reduction; D014810:Vitamin E / Q000737:chemistry*; D019207:beta Carotene / Q000737:chemistry*
D019207:beta Carotene; D014810:Vitamin E; D001205:Ascorbic Acid