title: Prevention of sudden cardiac death: management considerations.
abstract: Data, largely from randomized, controlled trials, have clarified the role of the various treatment modalities in preventing sudden cardiac death. The therapeutic usefulness in sudden cardiac death prevention of antirarrhythmic and other drugs, and of the implantable cardioverter-defibrillator, is discussed. The relative effectiveness of the various modalities is also considered and conclusions about an appropriate treatment paradigm and future research directions are discussed.
authors.affiliation: Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20892, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Domanski
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D003327:Coronary Disease / Q000150:complications; D016757:Death, Sudden, Cardiac / Q000209:etiology / Q000517:prevention & control*; D017147:Defibrillators, Implantable; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D018487:Ventricular Dysfunction, Left / Q000150:complications
chemical_list: D000889:Anti-Arrhythmia Agents