Evaluation of pleomorphic xanthoastrocytoma by use of positron emission tomography with.
We present a case of pleomorphic xanthoastrocytoma (PXA) in a patient with temporal lobe seizures. Imaging sequences included MR, and results of positron emission tomography (PET) with [18F]-fluorodeoxyglucose (FDG) and [11C]-methionine (Met) tracers revealed a hypermetabolic region equivalent or nearly equivalent to normal cerebral cortex, suggesting that the tumor might have malignant potential. Histopathologic findings indicated low-grade glioma. The mechanism for glucose hypermetabolic activity of PXA is not clear; however, the positive findings obtained from FDG-PET may not always indicate the degree of malignancy associated with PXA.
Tsuyuguchi
N
N
Department of Neurosurgery, Osaka City University Medical School, Osaka, Japan.
Matsuoka
Y
Y
Sunada
I
I
Matsusaka
Y
Y
Haque
M
M
D000328:Adult; D001254:Astrocytoma / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology; D002250:Carbon Radioisotopes; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging; D008715:Methionine; D011859:Radiography; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed
D002250:Carbon Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D008715:Methionine