title: Eosinophilic cholecystitis as a possible late manifestation of the eosinophilia-myalgia syndrome.
abstract: We describe a case of acute acalculous cholecystitis occurring in a 43-year-old woman with a history of the eosinophilia-myalgia syndrome, associated with the ingestion of 1-tryptophan. The patient underwent a laparoscopic cholecystectomy and subsequent histological examination of the gallbladder revealed an infiltrate predominantly of eosinophils, suggesting a possible relationship to the underlying condition. This may represent a late complication of the eosinophilia-myalgia syndrome--such an association has not previously been reported in the literature. The gastrointestinal and hepatic complications of this syndrome are discussed.
authors.affiliation: Department of Rheumatology, Watford General Hospital, UK.
authors.forename: A
authors.initials: A
authors.lastname: Hepburn
authors.forename: A
authors.initials: A
authors.lastname: Coady
authors.forename: J
authors.initials: J
authors.lastname: Livingstone
authors.forename: N
authors.initials: N
authors.lastname: Pandit
mesh_terms: D000328:Adult; D002764:Cholecystitis / Q000209:etiology* / Q000473:pathology* / Q000628:therapy; D018450:Disease Progression; D016603:Eosinophilia-Myalgia Syndrome / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006801:Humans; D016896:Treatment Outcome