[Effect of dorzolamide on accommodation and pupillary reaction?].
OBJECTIVE
To test the effect of dorzolamide on accommodation or pupillary function.


METHODS
This double-blind study examined 35 young subjects with normal ophthalmological findings. Before and after the application of two drops dorzolamide in one eye and placebo in the other eye the subjects were examined by pupillography, infrared video-retinoscopy, and subjective near-point determination.


RESULTS
None of the parameters concerning accommodation or pupillary function differed significantly before and after application of the eye drops.


CONCLUSIONS
Dorzolamide has no short-term effect on accommodation or pupillary function.
Pek
H
H
Universitäts-Augenklinik, Abt. für Pathophysiologie des Sehens und Neuroophthalmologie, Schleichstrasse 12-16, 72076 Tübingen.
Wilhelm
H
H
D000065:Accommodation, Ocular / Q000187:drug effects*; D000293:Adolescent; D000328:Adult; D002257:Carbonic Anhydrase Inhibitors / Q000494:pharmacology*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009883:Ophthalmic Solutions; D012025:Reflex, Pupillary / Q000187:drug effects*; D013449:Sulfonamides / Q000494:pharmacology*; D013876:Thiophenes / Q000494:pharmacology*
D002257:Carbonic Anhydrase Inhibitors; D009883:Ophthalmic Solutions; D013449:Sulfonamides; D013876:Thiophenes; C062765:dorzolamide