B-cell lymphoma in a patient with WHIM syndrome.
WHIM syndrome is a rare congenital familial syndrome consisting of warts, hypogammaglobulinemia, infections, and myelokathexis. We describe a 30-year-old man with WHIM syndrome, in whom red dermal facial nodules developed. The diagnosis of B-cell lymphoma was established with biopsy and immunohistochemical studies. To our knowledge, this is the first reported case of WHIM syndrome complicated by a B-cell lymphoma.
Chae
K M
KM
Department of Dermatology, Rush-Presbyterian-St Luke's Medical Center, Chicago, IL 60612-3864, USA.
Ertle
J O
JO
Tharp
M D
MD
D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications*; D006801:Humans; D007239:Infections / Q000150:complications; D016393:Lymphoma, B-Cell / Q000150:complications*; D008297:Male; D012878:Skin Neoplasms / Q000150:complications*; D013577:Syndrome; D014860:Warts / Q000150:complications*