[Therapy of lymphomatoid papulosis with balneo-PUVA-photochemotherapy]].
Lymphomatoid papulosis is a rare lymphoproliferative disorder of the skin. The standard therapeutic regimen is systemic (oral) photochemotherapy (PUVA). We examined the efficacy of PUVA-bath photochemotherapy in a patient requiring heart transplantation because of idiopathic dilatated cardiomyopathy and a relative contraindication against systemic 8-methoxypsoralen. The 42-years old male patient had suffered for 15 years with itching papules and plaques which clinically, immunohistochemically and molecular biologically were diagnosed as lymphomatoid papulosis. PUVA-bath photochemotherapy with 8-MOP was initiated. After 29 treatments the plaques disappeared completely. After 44 sessions (cumulative UV-A dose 206 J/cm2) the patient's skin almost was clear. PUVA-bath photochemotherapy proved to be a therapeutic alternative to systemic PUVA-treatment in this case of lymphomatoid papulosis.
Kowalzick
L
L
Hautklinik Vogtlandklinikum Plauen GmbH, Postfach 39, 08505 Plauen.
Ott
A
A
Waldmann
T
T
Suckow
M
M
Pönnighaus
J M
JM
D000328:Adult; D001452:Balneology; D003131:Combined Modality Therapy; D000075202:Contraindications; D016027:Heart Transplantation; D006801:Humans; D017731:Lymphomatoid Papulosis / Q000473:pathology / Q000628:therapy*; D008297:Male; D011701:PUVA Therapy; D012867:Skin / Q000473:pathology