title: Extraosseous epidural IgD myeloma presenting with compression myelopathy.
abstract: An 85-year-old man presented with acute transverse myelopathy: flaccid paraplegia, superficial and deep sensory disturbance below Th6 and loss of urinary sensation. Spinal magnetic resonance image showed an epidural mass compressing the spinal cord at the level of C7 to Th2. Immunoelectrophoresis revealed the presence of immunoglobulin D (IgD)-lambda M protein. Chemotherapy markedly improved both the haematologic aspect and tumor size, but not the motor deficit. In IgD myeloma, extraosseous spreads occur frequently, but extraosseous epidural tumors causing compression myelopathy are relatively rare. To our knowledge, this is the fourth report of cases.
authors.affiliation: Department of Neurology, Matsue Red Cross Hospital, Japan. yawatana@grape.med.tottori-u.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: A
authors.initials: A
authors.lastname: Endou
authors.forename: S
authors.initials: S
authors.lastname: Ooi
authors.forename: E
authors.initials: E
authors.lastname: Matsushima
authors.forename: Y
authors.initials: Y
authors.lastname: Shimisu
authors.forename: K
authors.initials: K
authors.lastname: Nakashima
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D007072:Immunoglobulin D; D008279:Magnetic Resonance Imaging; D008297:Male; D009101:Multiple Myeloma / Q000473:pathology*; D013117:Spinal Cord Compression / Q000473:pathology*; D013577:Syndrome
chemical_list: D007072:Immunoglobulin D