[Evaluation of FcR and CR receptor expression in granulocytes and immune complex level in patients with tick-borne encephalitis (TBE)].
The aim of this study was to estimate expression of FcR and CR membrane receptors of PMN and circulating immune complexes level in serum from infected patients before and after treatment. Before treatment we observed significant decrease of PMN percentage with FcR and CR receptors in comparison to control. After treatment there was increase of PMN percentage with receptors in comparison to values before treatment but it did not reach values of controls. Immune complexes level before treatment was significant higher than controls before treatment and it decreased after treatment but did not reach control level. Depression of phagocytic activity of PMN may be one of the main reasons for spreading viral infection.
Izycka
A
A
Zakładu Immunopatologii AM w Białymstoku.
Jabłońska
E
E
Zajkowska
J
J
Hermanowska-Szpakowicz
T
T
Izycki
T
T
D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis*; D004675:Encephalitis, Tick-Borne / Q000276:immunology* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000378:metabolism*; D010587:Phagocytosis; D011951:Receptors, Complement / Q000032:analysis*; D017452:Receptors, IgG / Q000032:analysis*
D000936:Antigen-Antibody Complex; D011951:Receptors, Complement; D017452:Receptors, IgG