title: Hijacking of apoptotic pathwaysby bacterial pathogens.
abstract: Increasing evidence indicates that apoptosis of the host cell may constitute a defense mechanism to confine the infection by bacterial pathogens. Certain pathogens have developed elegant mechanisms to modulate the fate of the host cell, which include induction or blockage of apoptosis. These studies will promote our understanding of the pathogenesis of infectious diseases and aid the development of means for therapeutic intervention.
authors.affiliation: Department of Microbiology and Immunology, University of Kentucky Chandler Medical Center, Lexington, KY 40536-0084, USA.
authors.forename: L
authors.initials: L
authors.lastname: Gao
authors.forename: Y
authors.initials: Y
authors.lastname: Abu Kwaik
mesh_terms: D000818:Animals; D017209:Apoptosis; D001419:Bacteria / Q000472:pathogenicity*; D001426:Bacterial Proteins; D001427:Bacterial Toxins; D020169:Caspases / Q000378:metabolism; D005098:Exotoxins; D006360:Heat-Shock Proteins; D006460:Hemolysin Proteins; D006801:Humans; D008565:Membrane Proteins; D008954:Models, Biological; D011749:Pyrogens
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins; D005098:Exotoxins; D006360:Heat-Shock Proteins; D006460:Hemolysin Proteins; D008565:Membrane Proteins; D011749:Pyrogens; C117980:SpeA protein, Streptococcus pyogenes; C027951:erythrogenic toxin; C021091:staphylococcal alpha-toxin; D020169:Caspases; C038705:hlyA protein, Listeria monocytogenes