title: [High dosage steroid pulse therapy. Is there an indication in dermatology?].
abstract: In recent years, high-dose steroid pulse therapy has been considered an effective treatment regimen in a number of non-dermatological diseases. This review addresses in the first part the pharmacological basics and mechanisms of action of high-dose glucocorticosteroid therapy. In the second part, we discuss the clinical experience using this treatment for dermatological diseases including pemphigus vulgaris, pyoderma gangrenosum, alopecia areata, and dermatomyositis.
authors.affiliation: Hautklinik und Poliklinik, Universitätskliniken des Saarlandes, Homburg/Saar. uwe.reinhold@med-rz.uni-sb.de
authors.forename: U
authors.initials: U
authors.lastname: Reinhold
authors.forename: F
authors.initials: F
authors.lastname: Buttgereit
mesh_terms: D001327:Autoimmune Diseases / Q000188:drug therapy* / Q000276:immunology; D004305:Dose-Response Relationship, Drug; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D020551:Pulse Therapy, Drug; D012871:Skin Diseases / Q000188:drug therapy* / Q000276:immunology
chemical_list: D005938:Glucocorticoids