Subcellular distribution of calponin and caldesmon in rat hippocampus.
Caldesmon and calponin are two actin- and calmodulin-binding proteins involved in the 'actin-linked' regulation of smooth muscle and non-muscle Mg(2+)-actin-activated myosin II ATPase activity. In the present report we show that caldesmon and calponin are present in the post-synaptic side of symmetric synapses and accumulate in the post-synaptic densities of asymmetric synapses. Caldesmon- and calponin-immunoreactivities are also observed at the plasma membrane of the hippocampal neurones. Finally, while caldesmon seems strictly distributed to neurones, acidic calponin is present in both neurones and astrocytes.
Agassandian
C
C
INMED/INSERM U29, Parc Scientifique de Luminy, 13009 Marseille Cedex, France.
Plantier
M
M
Fattoum
A
A
Represa
A
A
der Terrossian
E
E
D000818:Animals; D001253:Astrocytes / Q000166:cytology; D002135:Calcium-Binding Proteins / Q000032:analysis*; D002148:Calmodulin-Binding Proteins / Q000032:analysis*; D003712:Dendrites / Q000648:ultrastructure; D004591:Electrophoresis, Polyacrylamide Gel; D006624:Hippocampus / Q000737:chemistry* / Q000166:cytology*; D007150:Immunohistochemistry; D008840:Microfilament Proteins; D009457:Neuroglia / Q000166:cytology / Q000648:ultrastructure; D009474:Neurons / Q000166:cytology* / Q000648:ultrastructure; D009836:Oligodendroglia / Q000166:cytology; D051381:Rats; D013569:Synapses / Q000648:ultrastructure; D000096985:Calponins
D002135:Calcium-Binding Proteins; D002148:Calmodulin-Binding Proteins; D008840:Microfilament Proteins; D000096985:Calponins