title: Control of photon beam dose profiles by localized transverse magnetic fields.
abstract: Unlike electron beams, scant attention has been paid in the literature to possible magnetic field effects on therapeutic photon beams. Generally, dose profiles are considered to be fully determined by beam shape, photon spectrum and the substances in the beam path. Here we show that small superconducting magnets can exercise potentially useful control over photon dose profiles. The magnet produces a locally strong transverse field with large gradients and is applied to the tissue surface below which the photon beam is passing. For one practical magnet design, our simulations, which use the EGS-4 Monte Carlo code modified to include magnetic field effects, show significant intensification and shielding effects. In water phantoms, the effects extend to 3-4 cm or more beyond the warm face of the cryostat and greater distances are achieved in phantoms simulating lung (density approximately 0.3). Advances in applying the concept and in superconducting materials and magnet design hold promise for extending these ranges.
authors.affiliation: Exelar Corporation, Chicago, IL 60614, USA.
authors.forename: L
authors.initials: L
authors.lastname: Reiffel
authors.forename: A
authors.initials: A
authors.lastname: Li
authors.forename: J
authors.initials: J
authors.lastname: Chu
authors.forename: R W
authors.initials: RW
authors.lastname: Wheatley
authors.forename: S
authors.initials: S
authors.lastname: Naqvi
authors.forename: R
authors.initials: R
authors.lastname: Pillsbury
authors.forename: A
authors.initials: A
authors.lastname: Saxena
mesh_terms: D006801:Humans; D008168:Lung / Q000528:radiation effects; D008280:Magnetics; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D017785:Photons; D011874:Radiometry; D014867:Water
chemical_list: D014867:Water