title: [Role of bone marrow scintigraphy in defining the therapeutic approach  for some malignant tumors in children]  .
abstract: The data on scintigraphic examinations of the bone marrow (BM) carried out in 76 patients, aged 2-16, are evaluated. Focal, multi-focal and diffuse lesions were identified. Metastases to BM were detected in 6 out of 28 (21%) patients with Hodgkin's disease. Scintigraphic evidence played a role in working out treatment modalities in 4 cases. Metastatic foci located outside primary tumor were detected in 3 out of 26 (11.5%) patients with Ewing's sarcoma and scintigraphic findings were considered in all 3 cases when scope of radiotherapy and chemotherapy intensity were elaborated. Also, lesions to BM were found in 9 out of 22 (41%) patients with neuroblastoma. Radiotherapy was ruled out in 4 cases of multi-focal and diffuse lesions while all 5 patients with focal ones received it.
authors.affiliation: N.N. Petrov Research Institute of Oncology, the Ministry of Health of the RF, St. Petersburg.
authors.forename: S V
authors.initials: SV
authors.lastname: Kanaev
authors.forename: S N
authors.initials: SN
authors.lastname: Novikov
authors.forename: L A
authors.initials: LA
authors.lastname: Zhukova
authors.forename: A P
authors.initials: AP
authors.lastname: Malinin
authors.forename: B A
authors.initials: BA
authors.lastname: Kolygin
mesh_terms: D000293:Adolescent; D019046:Bone Marrow Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006689:Hodgkin Disease / Q000000981:diagnostic imaging / Q000628:therapy; D006801:Humans; D007223:Infant; D008297:Male; D009447:Neuroblastoma / Q000000981:diagnostic imaging / Q000628:therapy; D011877:Radionuclide Imaging; D012512:Sarcoma, Ewing / Q000000981:diagnostic imaging / Q000628:therapy