[Search for new methods of administering aminoglycoside antibiotics to attenuate side effects].
In the review some concepts of molecular mechanisms of nephrotoxic and ototoxic action of aminoglycosides was presented. The way to changes of aminoglycoside administration frequency, and reduction of side-effects was discussed.
Nowak
P
P
Katedra i Zakład Farmakologii w Zabrzu.
D000328:Adult; D000617:Aminoglycosides; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D004195:Disease Models, Animal; D004334:Drug Administration Schedule; D034381:Hearing Loss / Q000139:chemically induced / Q000517:prevention & control; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced / Q000517:prevention & control
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents