Prevalence of the APOC3 promoter polymorphisms T-455C and C-482T in Asian-Indians.
Potential mechanisms accounting for the high cardiovascular death rates observed in Asian-Indians are dyslipidemia and insulin resistance. Polymorphisms in the APOC3 promoter (-455 T/C and -482 C/T) were frequently encountered in young Asian-Indians and they correlated with reduced concentrations of apolipoprotein A-I.
Miller
M
M
Division of Cardiology, University of Maryland Medical Center, Baltimore, USA. mmiller@heart.umaryland.edu
Rhyne
J
J
Khatta
M
M
Parekh
H
H
Zeller
K
K
D000328:Adult; D001056:Apolipoproteins C / Q000235:genetics*; D003327:Coronary Disease / Q000208:ethnology* / Q000235:genetics*; D005260:Female; D006801:Humans; D007194:India / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D011110:Polymorphism, Genetic; D015995:Prevalence; D014481:United States; D044465:White People / Q000235:genetics*
D001056:Apolipoproteins C