title: Estimation of neonatal exposure after accidental ingestion of lufenuron in a breastfeeding mother.
abstract: A case of accidental anti-flea preparation (lufenuron) ingestion by a breastfeeding mother is reported. An estimation of infant exposure level was calculated based on the highest level measured. The breastfed infant was exposed to an average lufenuron dose of 0.032 mg/kg/day, which is only 3% of a reported acute overdose. No adverse effects were reported during 7 months of follow-up. Breastfeeding should be considered cautiously after consultation with a regional poison center in cases of accidental ingestion of this drug by a breastfeeding mother. The infant should be monitored for potential adverse effects.
authors.affiliation: Department of Neonatology, Hadassah University Hospital, Jerusalem, Israel.
authors.forename: B
authors.initials: B
authors.lastname: Bar-Oz
authors.forename: S
authors.initials: S
authors.lastname: Ito
authors.forename: V
authors.initials: V
authors.lastname: Parks
authors.forename: M P
authors.initials: MP
authors.lastname: Maurer
authors.forename: G
authors.initials: G
authors.lastname: Koren
mesh_terms: D000328:Adult; D000818:Animals; D000829:Animals, Domestic; D001549:Benzamides / Q000493:pharmacokinetics*; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007223:Infant; D007306:Insecticides / Q000493:pharmacokinetics*; D008895:Milk, Human / Q000737:chemistry*; D005466:Fluorocarbons
chemical_list: D001549:Benzamides; D007306:Insecticides; C070364:fluphenacur; D005466:Fluorocarbons