title: Benzo[c]phenanthridine bases and their antituberculosis activity.
abstract: The antituberculosis activity of fully-aromatized quaternary benzo[c]phenanthridine bases prepared in our laboratory was tested under the Tuberculosis Antimicrobial Acquisition and Coordinating Facility (TAACF) program. This review summarizes our syntheses of these bases and discusses their structure-activity relationships against primary tuberculosis.
authors.affiliation: Faculty of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi, Inage, Chiba 263-8522, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ishikawa
mesh_terms: D000995:Antitubercular Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D010616:Phenanthrenes / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D000995:Antitubercular Agents; D010616:Phenanthrenes