title: Evidence for bacterial causation of adverse pulpal responses in resin-based dental restorations.
abstract: The widespread use of resin and resin-monomers for bonding of dental restorations to dentin has occurred because of a fundamental shift in the view that injury to the pulp is induced by restorative procedures. While, for many years, the toxic effects of restorative materials were thought to be of crucial importance in the development of adverse pulpal responses, the key role of bacterial leakage at the restoration-tooth interface is now well-recognized. Consequently, if optimal conditions for the preservation of pulpal health are to be ensured, dental restorations should provide an impervious seal against the surrounding tooth structure. However, polymerization shrinkage and contraction stresses induced during setting, as well as a variety of technical difficulties encountered during the clinical operation, often produce less than perfect results. Therefore, modern restorative procedures involving resin and resin-bonded restoratives must still rely on the ability of the pulp to cope with the injurious elements to which it may be exposed during and after the procedure. This review examines factors that may govern the pulp's response to restorative procedures that involve adhesive technologies. An assessment is made of the risks involved as far as the continued vital function of the pulp is concerned. It is concluded that an intact, although thin, wall of primary dentin often enables the pulp to overcome both toxic material effects and the influences of bacterial leakage. In contrast, the pulp may not do equally well following capping of open exposures with resin composites. A dearth of controlled clinical studies in this area of dentistry calls for confirmation that pulpal health prevails over the long term following the use of total-etch and resin-bonding techniques.
authors.affiliation: Department of Endodontology and Oral Diagnosis, Faculty of Odontology, Göteborg University, Sweden. Gunnar.Bergenholtz@odontologi.gu.se
authors.forename: G
authors.initials: G
authors.lastname: Bergenholtz
mesh_terms: D000134:Acid Etching, Dental / Q000009:adverse effects; D000818:Animals; D003188:Composite Resins / Q000009:adverse effects*; D001840:Dental Bonding / Q000009:adverse effects*; D003736:Dental Cavity Lining; D003763:Dental Leakage / Q000150:complications*; D003782:Dental Pulp / Q000187:drug effects* / Q000382:microbiology* / Q000502:physiology; D003785:Dental Pulp Capping / Q000379:methods; D003789:Dental Pulp Exposure / Q000150:complications; D003790:Dental Pulp Necrosis / Q000209:etiology* / Q000517:prevention & control; D003793:Dental Restoration, Permanent / Q000009:adverse effects; D003804:Dentin / Q000502:physiology; D003806:Dentin Permeability; D006801:Humans; D019279:Resin Cements / Q000009:adverse effects; D014945:Wound Healing
chemical_list: D003188:Composite Resins; D019279:Resin Cements