title: Chordoid meningioma with polyclonal gammopathy. Case report.
abstract: The authors present a case of chordoid meningioma in a 55-year-old woman who manifested headache and personality change. Magnetic resonance imaging of the brain and cerebral angiography demonstrated a mass in the right frontal lobe that resembled a typical convexity meningioma. However, the pathological diagnosis was chordoid meningioma, a rare subtype of this tumor that usually occurs in adolescence and is known to be associated with Castleman syndrome. A meningothelial meningiomatous pattern suggestive of a meningothelial origin was focally present, and cytokeratin-positive squamoid cells were noted in the tumor. The lesion lacked dense infiltration of lymphocytes and plasma cells. Polyclonal gammopathy was the only sign of Castleman syndrome and hypochromic microcytic anemia was absent in this case. Polyclonal gammopathy resolved completely 6 months after total removal of the mass.
authors.affiliation: Department of Neurosurgery, Seoul National University College of Medicine, Korea.
authors.forename: D K
authors.initials: DK
authors.lastname: Lee
authors.forename: D G
authors.initials: DG
authors.lastname: Kim
authors.forename: G
authors.initials: G
authors.lastname: Choe
authors.forename: J G
authors.initials: JG
authors.lastname: Chi
authors.forename: H W
authors.initials: HW
authors.lastname: Jung
mesh_terms: D005871:Castleman Disease / Q000150:complications; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D008579:Meningioma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D010265:Paraproteinemias / Q000150:complications*