title: Surveillance of invasive Streptococcus pneumoniae infection in the province of Quebec, Canada, from 1996 to 1998: serotype distribution, Antimicrobial susceptibility, and clinical characteristics.
abstract: In the province of Quebec, Canada, from 1996 to 1998, 3,650 invasive Streptococcus pneumoniae infections were reported. A total of 1,354 isolates were serotyped and tested for antimicrobial susceptibility. The distribution of serotypes remained stable over the 3 years, with serotypes 14, 6B, 4, 9V, 23F, and 19F accounting for 61% of the isolates. Overall, 90% of isolates were included in the current 23-valent vaccine and 67% were included in the 7-valent conjugate vaccine. We were able to determine that resistance to penicillin and to other antibiotics is increasing.
authors.affiliation: Institut National de Santé Publique du Québec-Laboratoire de Santé Publique du Québec, Sainte-Anne-de-Bellevue, Quebec H9X 3R5, Canada. ljette@lspq.org
authors.forename: L P
authors.initials: LP
authors.lastname: Jetté
authors.forename: G
authors.initials: G
authors.lastname: Delage
authors.forename: L
authors.initials: L
authors.lastname: Ringuette
authors.forename: R
authors.initials: R
authors.lastname: Allard
authors.forename: P
authors.initials: P
authors.lastname: De Wals
authors.forename: F
authors.initials: F
authors.lastname: Lamothe
authors.forename: V
authors.initials: V
authors.lastname: Loo
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002648:Child; D004352:Drug Resistance, Microbial; D006801:Humans; D015994:Incidence; D008826:Microbial Sensitivity Tests; D011008:Pneumococcal Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D011792:Quebec / Q000453:epidemiology; D012621:Seasons; D012703:Serotyping; D022541:Streptococcal Vaccines; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000187:drug effects / Q000302:isolation & purification; D018074:Vaccines, Conjugate
chemical_list: D000900:Anti-Bacterial Agents; D022541:Streptococcal Vaccines; D018074:Vaccines, Conjugate