Assessment of neutrophil function in patients with septic shock: comparison of methods.
Patients with septic shock are shown to have decreased neutrophil phagocytic function by multiple assays, and their assessment by whole-blood assays (fluorescence-activated cell sorter analysis) correlates with assays requiring isolated neutrophils (microscopic and spectrophotometric assays). For patients with similar underlying conditions but without septic shock, this correlation does not occur.
Wenisch
C
C
Division of Infectious Diseases, Department of Internal Medicine I, University Hospital of Vienna, Vienna, Austria. christoph.wenisch@kfunigraz.ac.at
Fladerer
P
P
Patruta
S
S
Krause
R
R
Hörl
W
W
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004926:Escherichia coli; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D008856:Microscopy, Fluorescence / Q000379:methods; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology* / Q000382:microbiology; D012772:Shock, Septic / Q000097:blood / Q000276:immunology*