title: [Contractile function of ureter in its anomalies in children].
abstract: A study on the testing unit was made of a contractile function of ureteral fragments removed at reconstructive operations for vesicoureteral reflux (VUR), neuromuscular dysplasia (NMD) and pelvoureteral segment stricture (PUSS). The study parameters (wall rigidity, amplitude of the contractions, potassium depolarization contracture, responses to adrenoreactive drugs) in patients with VUR were close to normal, whereas in those with NMD or PUSS changed significantly, especially in PUSS patients. Ureteral contractility impairment was heterogenic in all the groups, varying from intact to lost and did not correlate either with age or the disease stage. The value of functional studies of the ureter in reconstructive surgery for specifying the disease pathogenesis, mechanisms of functional decline and individual prognosis of functional efficiency of the operative intervention is discussed.
authors.forename: V I
authors.initials: VI
authors.lastname: Kirpatovskiĭ
authors.forename: I S
authors.initials: IS
authors.lastname: Mudraia
authors.forename: A G
authors.initials: AG
authors.lastname: Pugachev
authors.forename: I N
authors.initials: IN
authors.lastname: Larionov
mesh_terms: D000293:Adolescent; D018663:Adrenergic Agents; D018674:Adrenergic Antagonists; D002648:Child; D002675:Child, Preschool; D004558:Electric Stimulation; D006801:Humans; D066298:In Vitro Techniques; D007552:Isotonic Solutions; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology*; D009130:Muscle, Smooth / Q000187:drug effects / Q000503:physiopathology*; D011379:Prognosis; D014513:Ureter / Q000002:abnormalities* / Q000187:drug effects / Q000503:physiopathology; D014517:Ureteral Obstruction / Q000151:congenital* / Q000503:physiopathology / Q000601:surgery; D014718:Vesico-Ureteral Reflux / Q000151:congenital* / Q000503:physiopathology / Q000601:surgery
chemical_list: D018663:Adrenergic Agents; D018674:Adrenergic Antagonists; D007552:Isotonic Solutions; C010380:Locke's solution