title: Antifungal amides from Piper hispidum and Piper tuberculatum.
abstract: Piper hispidum and Piper tuberculatum accumulate amides bearing isobutyl, pyrrolidine, dihydropyridone and piperidine moieties. The isolation and characterization of several representatives including two hitherto unreported amides were performed by chromatographic techniques and by analysis of spectroscopic data. The antifungal activity of each amide was determined by direct bioautography against Cladosporium sphaerospermum.
authors.affiliation: Instituto de Química, Universidade Estadual Paulista, Araraquara-SP, Brazil.
authors.forename: H M
authors.initials: HM
authors.lastname: Navickiene
authors.forename: A C
authors.initials: AC
authors.lastname: Alécio
authors.forename: M J
authors.initials: MJ
authors.lastname: Kato
authors.forename: V D
authors.initials: VD
authors.lastname: Bolzani
authors.forename: M C
authors.initials: MC
authors.lastname: Young
authors.forename: A J
authors.initials: AJ
authors.lastname: Cavalheiro
authors.forename: M
authors.initials: M
authors.lastname: Furlan
mesh_terms: D000577:Amides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002963:Cladosporium / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry*; D008826:Microbial Sensitivity Tests
chemical_list: D000577:Amides; D000935:Antifungal Agents