title: Long-term outcome of surgical management for diffuse jejunoileal Crohn's disease.
abstract: BACKGROUND
  In diffuse jejunoileal Crohn's disease, resectional surgery may lead to short-bowel syndrome. Since 1980 strictureplasty has been used for jejunoileal strictures. This study reviews the long-term outcome of surgical treatment for diffuse jejunoileal Crohn's disease.
  
  
  METHODS
  The cases of 46 patients who required surgery for diffuse jejunoileal Crohn's disease between 1980 and 1997 were reviewed.
  
  
  RESULTS
  Strictureplasty was used for short strictures without perforating disease (perforation, abscess, fistula). Long strictures (<20 cm) or perforating disease was treated with resection. During an initial operation, strictureplasty was used on 63 strictures in 18 patients (39%). After a median follow-up of 15 years, there were 3 deaths: 1 from postoperative sepsis, 1 from small-bowel carcinoma, and 1 from bronchogenic carcinoma. Thirty-nine patients required 113 reoperations for jejunoileal recurrence. During 75 of the 113 reoperations (66%), strictureplasty was used on 315 strictures. Only 2 patients experienced the development of short-bowel syndrome and required home parenteral nutrition. At present, 4 patients are symptomatic and require medical treatment. All other patients are asymptomatic and require neither medical treatment nor nutritional support.
  
  
  CONCLUSIONS
  Most patients with diffuse jejunoileal Crohn's disease can be restored to good health with minimal symptoms by surgical treatment that includes strictureplasty.
authors.affiliation: University Department of Surgery, Queen Elizabeth Hospital, Birmingham, UK.
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
authors.forename: R N
authors.initials: RN
authors.lastname: Allan
authors.forename: M R
authors.initials: MR
authors.lastname: Keighley
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003424:Crohn Disease / Q000601:surgery*; D005260:Female; D006801:Humans; D007079:Ileitis / Q000601:surgery; D007579:Jejunal Diseases / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D012008:Recurrence; D012086:Reoperation; D012778:Short Bowel Syndrome / Q000209:etiology; D013997:Time Factors; D016896:Treatment Outcome