title: [Bilateral sino-orbital mucormycosis. A case report].
abstract: We report a case of mucormycosis in a 48 year-old diabetic woman. She presented with nasosinusal ulcer accompanied by panophthalmitis in the left eye and central retinal artery occlusion in the right eye. Left eye enucleation was performed and the diagnosis of mucormycosis was made on histopathologic examination displaying fungal micro-organisms in the optic nerve and in the retina. The patient died of stress ulcer hemorrhage. Mucormycoses are rare and severe diseases affecting immunocompromised hosts, especially diabetic patients during ketoacidosis. The treatment includes surgical debridement and amphotericin B but prognosis remains severe.
authors.affiliation: Service d'Ophtalmologie, Hôpital Lariboisière, Paris. paques@lrb.ap-hop-paris.fr
authors.forename: M
authors.initials: M
authors.lastname: Paques
authors.forename: M
authors.initials: M
authors.lastname: Wassef
authors.forename: B
authors.initials: B
authors.lastname: Faucon
authors.forename: A
authors.initials: A
authors.lastname: Erginay
authors.forename: A
authors.initials: A
authors.lastname: Gaudric
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003646:Debridement; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D015353:Eye Enucleation; D015821:Eye Infections, Fungal / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009090:Mucorales / Q000302:isolation & purification; D009091:Mucormycosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009900:Optic Nerve / Q000382:microbiology / Q000473:pathology; D012160:Retina / Q000382:microbiology / Q000473:pathology
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B