title: Aneurysm sac pressure measurements after endovascular repair of abdominal aortic aneurysms.
abstract: OBJECTIVE
  The goal of endovascular grafting of abdominal aortic aneurysms (AAAs) is to exclude the aneurysm sac from systemic pressure and thereby decrease the risk of rupture. Unlike conventional open surgery, branch vessels in the sac (eg, lumbar artery and inferior mesenteric artery [IMA]) are not ligated and can potentially transmit pressure. The purpose of our investigation was to evaluate the feasibility of various interventional techniques for measuring pressure within the aneurysm sac in patients who had undergone endovascular repair of AAAs.
  
  
  METHODS
  Sac pressure measurements were performed in 21 patients who had undergone stent graft repair of AAAs. Seventeen of 21 patients had endoleaks demonstrated on 30-day computed tomographic (CT) scans. Access to the aneurysm sac in these patients was through direct translumbar sac puncture (5 patients), through a patent IMA accessed via the superior mesenteric artery (SMA) (9 patients), or by direct cannulation around attachment sites (3 patients). Four patients had perioperative pressure measurements obtained through catheters positioned along side of the endovascular graft at the time of its deployment. Two of these catheters were left in position for 30 hours during which time CT and conventional angiography were performed. Pressures were determined with standard arterial-line pressure transduction techniques and compared with systemic pressure in each patient.
  
  
  RESULTS
  Elevated sac pressure was found in all patients. The sac pressure in patients with endoleaks was found to be systemic (15 patients) or near systemic (2 patients) and all had pulsatile waveforms. Elevated sac pressures were also found in patients without CT or angiographic evidence of endoleak (2 patients). Injection of the sacs in two of these patients revealed a patent lumbar artery and an IMA.
  
  
  CONCLUSIONS
  It is possible to measure pressures from within the aneurysm sac in patients with stent grafts with a variety of techniques. Patients may continue to have pressurized AAA sacs despite endovascular AAA repair. Endoleaks transmit pulsatile pressure into the aneurysm sac regardless of the type. It is possible to have systemic sac pressures without evidence of endoleaks on CT or angiography.
authors.affiliation: Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, 19104, USA. baumr@rad.upenn.edu
authors.forename: R A
authors.initials: RA
authors.lastname: Baum
authors.forename: J P
authors.initials: JP
authors.lastname: Carpenter
authors.forename: C
authors.initials: C
authors.lastname: Cope
authors.forename: M A
authors.initials: MA
authors.lastname: Golden
authors.forename: O C
authors.initials: OC
authors.lastname: Velazquez
authors.forename: D G
authors.initials: DG
authors.lastname: Neschis
authors.forename: M E
authors.initials: ME
authors.lastname: Mitchell
authors.forename: C F
authors.initials: CF
authors.lastname: Barker
authors.forename: R M
authors.initials: RM
authors.lastname: Fairman
mesh_terms: D000800:Angioplasty, Balloon; D017544:Aortic Aneurysm, Abdominal / Q000503:physiopathology / Q000601:surgery*; D001027:Aortography; D001794:Blood Pressure / Q000502:physiology*; D019917:Blood Vessel Prosthesis Implantation; D004621:Embolization, Therapeutic; D006801:Humans; D011183:Postoperative Complications / Q000503:physiopathology* / Q000628:therapy; D011237:Predictive Value of Tests; D019233:Retreatment; D015607:Stents; D014057:Tomography, X-Ray Computed