Successful treatment of antiepileptic drug hypersensitivity syndrome with intravenous immune globulin.
Intravenous immune globulin (IVIG) has proved beneficial for severe immunologically related cutaneous adverse reactions. We report a child with severe antiepileptic drug hypersensitivity syndrome who was successfully treated with IVIG. IVIG should be considered in the pharmacologic armamentarium of severe antiepileptic drug hypersensitivity syndrome. antiepileptic drugs, hypersensitivity, immune globulin.
Scheuerman
O
O
Department of Pediatrics A and Units of, Schneider Children's Medical Center of Israel, Petah Tiqva.
Nofech-Moses
Y
Y
Rachmel
A
A
Ashkenazi
S
S
D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D003875:Drug Eruptions / Q000188:drug therapy / Q000209:etiology; D004342:Drug Hypersensitivity / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D008590:Meningoencephalitis / Q000150:complications; D010672:Phenytoin / Q000009:adverse effects* / Q000627:therapeutic use; D012640:Seizures / Q000188:drug therapy / Q000209:etiology; D013577:Syndrome; D016896:Treatment Outcome
D000927:Anticonvulsants; D016756:Immunoglobulins, Intravenous; D010672:Phenytoin