title: Prolactin levels and autoantibodies in female patients with systemic lupus erythematosus.
abstract: We investigated the relationships between prolactin (PRL) levels and antibody occurrence in systemic lupus erythematosus (SLE). No significant association between PRL levels and the majority of the autoantibodies studied (anti-U1 RNP, anti-rRNP, anti-Sm, anti-dsDNA, anti-DNP, auto-LCA, anti-EACA) could be confirmed (P > 0.05), anti-Ro/SSA antibodies being an exception. Our results showed significantly increased frequencies of these antibodies in the group of female SLE patients with normal PRL levels (< 20 micrograms/L): anti Ro/SSA in 53% (P < 0.025, chi 2 = 5.80, RR = 4.0) and anti-Ro/SSA + anti-Ro/La in 60% (P < 0.05, chi 2 = 4.05) compared with female SLE patients with hyperprolactinemia.
authors.affiliation: Research Institute of Rheumatic Diseases, Nábrezie I. Krasku 92101 Piestăny, Slovak Republic.
authors.forename: D
authors.initials: D
authors.lastname: Kozáková
authors.forename: J
authors.initials: J
authors.lastname: Rovenský
authors.forename: L
authors.initials: L
authors.lastname: Cebecauer
authors.forename: V
authors.initials: V
authors.lastname: Bosák
authors.forename: E
authors.initials: E
authors.lastname: Jahnová
authors.forename: M
authors.initials: M
authors.lastname: Vigas
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D001323:Autoantibodies / Q000097:blood*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D008875:Middle Aged; D011388:Prolactin / Q000097:blood*; D012016:Reference Values
chemical_list: D000974:Antibodies, Antinuclear; D001323:Autoantibodies; C035356:SS-A antibodies; D011388:Prolactin