Ommaya-catheter-related Staphylococcus epidermidis cerebritis and recurrent bacteremia documented by molecular typing.
A 26-year-old woman receiving intrathecal chemotherapy for acute leukemia developed Ommaya-catheter-associated cerebritis and bacteremia caused by two clones of Staphylococcus epidermidis. Genomic fingerprinting of 19 staphylococcal isolates from the cerebrospinal fluid, blood, catheter and skull biopsy was necessary to establish the etiologic diagnosis and to guide medical and surgical therapy.
Hakim
A
A
Service de Microbiologie, Hopital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
Rossi
C
C
Kabanda
A
A
Deplano
A
A
De Gheldre
Y
Y
Struelens
M J
MJ
D000328:Adult; D016470:Bacteremia / Q000382:microbiology*; D015373:Bacterial Typing Techniques; D001769:Blood / Q000382:microbiology; D002404:Catheterization / Q000009:adverse effects; D002408:Catheters, Indwelling / Q000382:microbiology*; D002555:Cerebrospinal Fluid / Q000382:microbiology; D016521:Electrophoresis, Gel, Pulsed-Field; D004660:Encephalitis / Q000382:microbiology*; D004866:Equipment Contamination; D005260:Female; D006801:Humans; D016133:Polymerase Chain Reaction; D013203:Staphylococcal Infections / Q000382:microbiology; D013212:Staphylococcus epidermidis / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification