title: Dipole analysis of ultralate (C-fibres) evoked potentials after laser stimulation of tiny cutaneous surface areas in humans.
abstract: Ultralate (C-fibres) laser evoked potentials (LEP) can be obtained by stimulation of a tiny skin surface area (0.23 mm(2)). Since their generators are unknown up to now, we performed brain source analyses of ultralate LEPs using high resolution electroencephalography (64 channels) and a realistic head model that was based on individual magnetic resonance images. Ultralate LEPs were characterized by a negative-positive complex with a large positive component maximal at the vertex. Source analysis revealed that ultralate LEPs could be explained by two dipole sources in the upper bank of the contralateral and ipsilateral Sylvian fissure (SII) and one dipole in the median region corresponding to the anterior cingulate gyrus.
authors.affiliation: Faculty of Medicine, Université Catholique de Louvain, Avenue Mounier 53/READ 5375, B-1200, Brussels, Belgium. opsommer@read.ucl.ac.be
authors.forename: E
authors.initials: E
authors.lastname: Opsommer
authors.forename: T
authors.initials: T
authors.lastname: Weiss
authors.forename: L
authors.initials: L
authors.lastname: Plaghki
authors.forename: W H
authors.initials: WH
authors.lastname: Miltner
mesh_terms: D000328:Adult; D001931:Brain Mapping; D004569:Electroencephalography; D005071:Evoked Potentials; D007839:Functional Laterality; D006801:Humans; D007834:Lasers; D008279:Magnetic Resonance Imaging; D009412:Nerve Fibers / Q000502:physiology*; D012879:Skin Physiological Phenomena