Linear lesion formation by ND:YAG laser versus radiofrequency energy in porcine atria.
The efficacy of RF energy versus the neodymium:yittrium aluminum-garnet laser to create linear lesions was compared in fresh ex vivo swine hearts. A total of 598 lesions were created in four locations: ostium of the pulmonary veins, trabeculated lateral left atrium, smooth posterior part of the right atrium, and the isthmus between the inferior vena cava and tricuspid valve. A 400-micron bare quartz fiber with CO2 cooling (distance to the tissue 5, 10, and 15 mm) and an RF ablation catheter (4-mm tip) were mechanically dragged over the tissue at speeds 0.5, 1.0, and 1.5 mm/s. A continuous and transmural ablation line was recorded as successful. A 100% success rate was achieved at the pulmonary veins and the isthmus at some settings of energy delivery by the laser and RF. In the thick posterior right atrium, RF resulted in transmural lesions only when associated with carbonization, while the laser produced successful ablation lines in 100% of the attempts. In the left atrium, because of the presence of prominent trabeculations, RF was unsuccessful at all settings of energy delivery. In contrast, deep photocoagulation by laser resulted in successful ablations in the left atrium in 100% of attempts. Lesion formation was faster by laser ablation and mean lesion width was at least 25% smaller with the laser than with RF. In conclusion, the formation of linear lesions at the isthmus and at the pulmonary veins was successful with the laser and RF. In the trabeculated left atrium and the thick posterior right atrium, only laser ablation was successful.
Menz
V
V
Department of Cardiology, Philipps-University of Marburg, Marburg, Germany. Pruente@mailer.uni-marburg.de
Scholz
S
S
Baumgärtel
D
D
Hoffmann
J
J
Grimm
W
W
Moosdorf
R
R
Maisch
B
B
D000818:Animals; D017115:Catheter Ablation; D006325:Heart Atria / Q000601:surgery*; D066298:In Vitro Techniques; D053685:Laser Therapy; D011667:Pulmonary Veins / Q000601:surgery; D015203:Reproducibility of Results; D013552:Swine; D014261:Tricuspid Valve; D014682:Vena Cava, Inferior