title: Recent developments in amoebiasis:the Gal/GalNAc lectins of Entamoeba histolytica and Entamoeba dispar.
abstract: Amoebiasis is responsible for 50000-100000 deaths annually. Invasive amoebic disease begins with the attachment of Entamoeba histolytica trophozoites to colonic mucin, a process mediated by the amoebic Gal/GalNAc lectin. The non-pathogenic counterpart, E. dispar, is morphologically identical but genetically distinct. Investigations comparing the Gal/GalNac lectin from these two organisms are under way.
authors.affiliation: Division of Infectious Disease, Department of Medicine, University Health Network and University of Toronto, Ontario, Canada.
authors.forename: D R
authors.initials: DR
authors.lastname: Pillai
authors.forename: K C
authors.initials: KC
authors.lastname: Kain
mesh_terms: D000562:Amebiasis / Q000209:etiology*; D000818:Animals; D002352:Carrier Proteins / Q000502:physiology*; D004747:Entamoeba / Q000472:pathogenicity*; D004748:Entamoeba histolytica / Q000472:pathogenicity; D037102:Lectins / Q000502:physiology*; D037181:Lectins, C-Type; D008565:Membrane Proteins; D016052:Protozoan Vaccines / Q000276:immunology
chemical_list: D002352:Carrier Proteins; D037102:Lectins; D037181:Lectins, C-Type; D008565:Membrane Proteins; D016052:Protozoan Vaccines