title: A new synthesis of indoloquinolizines by Pictet-Spengler reaction of tryptamine type 1,2-dihydropyridines utilizing sec-nitrodienamine.
abstract: The Pictet-Spengler reaction of tryptamine type 1,2-dihydropyridine 5c derived from the cycloaddition of the sec-nitrodienamine 3c with acetaldehyde afforded the indoloquinolizine derivatives 6 and 7.
authors.affiliation: Showa Pharmaceutical University, Machida, Tokyo, Japan. koike@ac.shoyaku.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Koike
authors.forename: Y
authors.initials: Y
authors.lastname: Shinohara
authors.forename: S
authors.initials: S
authors.lastname: Tobinaga
authors.forename: N
authors.initials: N
authors.lastname: Takeuchi
mesh_terms: D002070:Butadienes / Q000737:chemistry*; D004095:Dihydropyridines / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D009574:Nitro Compounds / Q000737:chemistry*; D011807:Quinolizines / Q000138:chemical synthesis* / Q000737:chemistry; D014363:Tryptamines / Q000737:chemistry*
chemical_list: C423464:1-(2-(3-indolyl)ethylamino)-4-nitro-1,3-butadiene; D002070:Butadienes; D004095:Dihydropyridines; D007211:Indoles; D009574:Nitro Compounds; D011807:Quinolizines; D014363:Tryptamines; C030820:tryptamine; C038806:1,4-dihydropyridine