title: Head and neck squamous cell carcinoma: US-guided fine-needle aspiration of sentinel lymph nodes for improved staging--initial experience.
abstract: Ultrasonography (US)-guided fine-needle aspiration with cytologic examination was combined with lymphoscintigraphy for the identification of sentinel lymph nodes (SLNs) in 12 patients with a squamous cell carcinoma of the oral cavity or oropharynx. Dynamic lymphoscintigraphy and a hand-held gamma probe were used to depict the SLNs to be aspirated. Cytologic examination of the aspirated SLNs revealed neck lymph node status in patients who underwent neck dissection (n = 6). In patients who underwent only transoral excision, one false-negative cytologic result was observed. This combined approach is expected to improve the detection of occult neck lymph node metastases.
authors.affiliation: Department of Otolaryngology/Head and Neck Surgery, University Hospital Vrije Universiteit, De Boelelaan 1117, PO Box 7057, 1007 MB Amsterdam, The Netherlands.
authors.forename: D R
authors.initials: DR
authors.lastname: Colnot
authors.forename: E J
authors.initials: EJ
authors.lastname: Nieuwenhuis
authors.forename: M W
authors.initials: MW
authors.lastname: van den Brekel
authors.forename: R
authors.initials: R
authors.lastname: Pijpers
authors.forename: R H
authors.initials: RH
authors.lastname: Brakenhoff
authors.forename: G B
authors.initials: GB
authors.lastname: Snow
authors.forename: J A
authors.initials: JA
authors.lastname: Castelijns
mesh_terms: D000368:Aged; D001707:Biopsy, Needle / Q000379:methods; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000473:pathology*; D005240:Feasibility Studies; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010865:Pilot Projects; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D014463:Ultrasonography