title: Age-related changes of the MR appearance of CNS involvement in neurocutaneous melanosis complex.
abstract: We report a case of giant congenital melanocytic nevi (GCMN) at risk of developing neurocutaneous melanosis (NCM) with age-related changes observable on MRI of the brain. However, although the usefulness of MR imaging in NCM is well known, age-related changes on MRI have rarely been reported. The prevalence of positive MRI findings and prognosis in GCMN accompanied by epilepsy and/or mental retardation awaits clarification. This case report may suggest the importance of serial brain MRI in cases of GCMN in assessing the risk of NCM.
authors.affiliation: Department of Paediatrics, Faculty of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. kgondo@pediatr.med.kyushu-u.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Gondo
authors.forename: R
authors.initials: R
authors.lastname: Kira
authors.forename: Y
authors.initials: Y
authors.lastname: Tokunaga
authors.forename: T
authors.initials: T
authors.lastname: Hara
mesh_terms: D000367:Age Factors; D001932:Brain Neoplasms / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009508:Nevus, Pigmented / Q000175:diagnosis*