title: [Recurrence-free and recurrent urolithiasis: metabolic differences].
abstract: Biochemical tests by 12 metabolic blood and urine indices reflecting the condition of renal function and metabolism of urolithogenic substances were made in the course of 1-6 year follow-up of 35 and 79 patients (46 females and 68 males aged 18-65 years) with recurrence-free and recurrent urolithiasis, respectively. The risk of recurrence for uric acid urolithiasis in serum concentration of urea 5.67 +/- 0.14 mmol/l and creatinine 0.090 +/- 0.008 mmol/l, in hyperuricemia and hyperuricuria was associated with elevation of renal excretion of total calcium to 5.88 +/- 0.49 mmol/day and ratio of daily renal excretion of sodium to renal daily excretion of potassium to 3.28 +/- 0.08; for calcium-oxalate lithiasis--with a rise in serum concentration of uric acid to 0.310 +/- 0.042 mmol/l and sodium to 114 +/- 0.8 mmol/l in hypercalciuria and hyperuricuria.
authors.forename: O V
authors.initials: OV
authors.lastname: Konstantinova
authors.forename: E K
authors.initials: EK
authors.lastname: Ianenko
authors.forename: N K
authors.initials: NK
authors.lastname: Dzeranov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood / Q000652:urine; D002118:Calcium / Q000652:urine*; D002940:Circadian Rhythm; D003404:Creatinine / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000652:urine; D012008:Recurrence; D012307:Risk Factors; D012964:Sodium / Q000652:urine; D014508:Urea / Q000097:blood*; D014527:Uric Acid / Q000652:urine*; D014545:Urinary Calculi / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D014527:Uric Acid; D014508:Urea; D012964:Sodium; D003404:Creatinine; D011188:Potassium; D002118:Calcium