title: Lymph nodal involvement by renal angiomyolipoma.
abstract: Angiomyolipoma of the kidney is a clonal neoplasm, apparently part of a family of neoplasms derived from perivascular epithelial cells. A 40-year-old woman presented with right flank pain and an otherwise non-significant medical history. An abdominal computed tomography scan revealed an 18 cm solid mass in the mid-portion of the right kidney and multiple perihilar lymph nodes. Presumptive diagnosis was renal cell carcinoma. Right radical nephrectomy and a perihilar lymph node dissection was performed through a Chevron incision for the anticipated diagnosis of renal adenocarcinoma. The renal tumor was diagnosed as angiomyolipoma and a component was identified pathologically in a dissected lymph node. There was no evidence of tumor recurrence in the follow-up period of eight years. The consensus from other studies suggests that this phenomenon is a manifestation of the multicentric nature of angiomyolipoma, rather than due to metastasis. Genetic studies may resolve this question in the future.
authors.affiliation: Department of Urology, Faculty of Medicine, Istanbul University, Turkey. usta@med.akdeniz.edu.tr
authors.forename: I
authors.initials: I
authors.lastname: Türker Köksal
authors.forename: M
authors.initials: M
authors.lastname: Tunç
authors.forename: I
authors.initials: I
authors.lastname: Kiliçaslan
authors.forename: H
authors.initials: H
authors.lastname: Ander
authors.forename: F
authors.initials: F
authors.lastname: Ozcan
authors.forename: T
authors.initials: T
authors.lastname: Kaplancan
mesh_terms: D000328:Adult; D018207:Angiomyolipoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology*; D008207:Lymphatic Metastasis; D009392:Nephrectomy; D014057:Tomography, X-Ray Computed