[Role of secondary phosphoinositide messengers in storage of Ca2+ ions in retinal rod microsomes].
The influence of guanosine-5'-triphosphate and secondary messengers forming in rod outer segment membranes during light-stimulated hydrolysis of phosphoinositides on the ATP-dependent Ca(2+)-uptake in microsomes of the retinal rod inner segment was studied. The water-soluble cytoplasmic components of the retinal rod outer segment were shown to be capable of stimulating the Ca(2+)-pump of endoplasmic reticulum after light illumination. This process is likely to proceed with the participation of 1,2-diacylglycerol localized in microsome membrane.
Emel'ianova
V P
VP
Institute of Photobiology, Belorussian Academy of Sciences, ul. Academicheskaya 27, Minsk, 220072 Belarus.
Baranova
L A
LA
Volotovskiĭ
I D
ID
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002413:Cations, Divalent; D006160:Guanosine Triphosphate / Q000502:physiology; D008861:Microsomes / Q000378:metabolism*; D010716:Phosphatidylinositols / Q000502:physiology*; D017948:Retinal Rod Photoreceptor Cells / Q000378:metabolism*; D015290:Second Messenger Systems / Q000502:physiology*
D002413:Cations, Divalent; D010716:Phosphatidylinositols; D006160:Guanosine Triphosphate; D000255:Adenosine Triphosphate; D002118:Calcium