title: [Prospective study of correlation between diabetic retinopathy and microalbuminuria in diabetes type 1 patients].
abstract: OBJECTIVE
  To determine the relationship between microalbuminuria and diabetic retinopathy.
  
  
  METHODS
  Prospective study of 5 years duration in 104 younger-onset diabetic patients; the diabetic retinopathy diagnosis was made by fundus retinography, and determination of microalbuminuria in 6 months time intervals.
  
  
  RESULTS
  The incidence of diabetic retinopathy was 33 patients (31.73%), the epidemiological factors implicated were diabetes duration, sex (men), high levels of HbA1c, high diastolic blood pressure, and high levels of HDL-cholesterol in inverse mode. The incidence of microalbuminuria was 25 patients (24.03%), the epidemiological factors implicated were high levels of HbA1c and the presence of high diastolic blood pressure. The association between microalbuminuria and diabetic retinopathy results in 4 groups of patients, 63 patients with neither microalbuminuria nor retinopathy. 17 patients developed microalbuminuria and diabetic retinopathy, 16 patients developed retinopathy but not microalbuminuria and 8 patients developed only microalbuminuria. The group of patients with microalbuminuria and retinopathy were associated with higher levels of HbA1c, high diastolic blood pressure and high levels of Total-cholesterol and HDL-cholesterol ; the group with only retinopathy was associated with diabetes duration and high levels of triglycerides.
  
  
  CONCLUSIONS
  In the population studied the microalbuminuria was not a good marker for diabetic retinopathy.
authors.affiliation: Unidad de Oftalmología, Hospital Universitario San Joan Reus, Departamento de Medicina y Cirugía, Universidad Rovira y Virgili, 43202 Reus (Tarragona), Spain.
authors.forename: P R
authors.initials: PR
authors.lastname: Aroca
authors.forename: O
authors.initials: O
authors.lastname: Espeso Sentís
authors.forename: D D
authors.initials: DD
authors.lastname: Del Castillo
mesh_terms: D000293:Adolescent; D000328:Adult; D000419:Albuminuria / Q000150:complications*; D000704:Analysis of Variance; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000175:diagnosis; D003928:Diabetic Nephropathies / Q000150:complications*; D003930:Diabetic Retinopathy / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012044:Regression Analysis; D012307:Risk Factors; D014792:Visual Acuity