Severe ethylene glycol ingestion treated without hemodialysis.
Fomepizole (4-methylpyrazole, Antizol) is being increasingly used in the treatment of ethylene glycol toxicity in adults. Little experience exists with this drug, however, in the pediatric population. We present a case of ethylene glycol poisoning in a child where use of fomepizole averted intravenous ethanol infusion and hemodialysis, limited the duration of intensive care monitoring, and decreased the overall cost of treatment.
Boyer
E W
EW
Denver, CO 80262, USA. boyer_e@hub.tch.harvard.edu
Mejia
M
M
Woolf
A
A
Shannon
M
M
D000293:Adolescent; D000931:Antidotes / Q000627:therapeutic use*; D000431:Ethanol / Q000008:administration & dosage; D019855:Ethylene Glycol / Q000506:poisoning*; D005260:Female; D000077604:Fomepizole; D006801:Humans; D007262:Infusions, Intravenous; D011041:Poisoning / Q000628:therapy*; D011720:Pyrazoles / Q000627:therapeutic use*; D006435:Renal Dialysis
D000931:Antidotes; D011720:Pyrazoles; D000431:Ethanol; D000077604:Fomepizole; D019855:Ethylene Glycol