title: AIDS oncology.
abstract: Kaposi's sarcoma, non-Hodgkin's lymphoma, Hodgkin's disease, and squamous cell carcinoma are among the malignancies seen with increased frequency in patients infected with HIV. The outlook for patients with these malignancies has improved significantly with the utilization of highly active antiretroviral therapy (HAART) and more aggressive cytotoxic therapies. Novel biologic therapies with lesser side effects are currently being evaluated. This article reviews the current knowledge about HIV malignancies, their epidemiology, pathogenesis, clinical manifestations, and treatment.
authors.affiliation: AIDS Research Center and MGH Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: P G
authors.initials: PG
authors.lastname: O'Connor
authors.forename: D T
authors.initials: DT
authors.lastname: Scadden
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006689:Hodgkin Disease / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D008297:Male; D012514:Sarcoma, Kaposi / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents