Synthesis and characterization of drug-enzyme conjugates.
Two drug-enzyme conjugates of dexamethasone-subtilisin and dexamethasone-cellulase have been synthesized and characterized to study their drug-protein incorporation ratio, immunoreactivity, enzyme activity and stability and these studies proved that a variety of drug enzyme conjugates could also be synthesized and characterized.
Saeed-ul-Hassan
S
S
Faculty of Pharmacy, University of the Punjab, Lahore, Pakistan.
Rowel
F J
FJ
D000893:Anti-Inflammatory Agents / Q000737:chemistry*; D002480:Cellulase / Q000737:chemistry*; D002850:Chromatography, Gel; D003907:Dexamethasone / Q000737:chemistry*; D004797:Enzyme-Linked Immunosorbent Assay; D005456:Fluorescent Dyes; D007202:Indicators and Reagents; D007546:Isoquinolines; D020112:Rhodamine 123 / Q000737:chemistry; D012710:Serum Albumin, Bovine / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013381:Subtilisins / Q000737:chemistry*
D000893:Anti-Inflammatory Agents; D005456:Fluorescent Dyes; D007202:Indicators and Reagents; D007546:Isoquinolines; D020112:Rhodamine 123; D012710:Serum Albumin, Bovine; D003907:Dexamethasone; C017475:lucifer yellow; D002480:Cellulase; D013381:Subtilisins