Enzyme inactivation by TiO2 photosensitization.
The enzyme horseradish peroxidase is extensively inactivated by UVA exposure in the presence of TiO2, a common ingredient of sunscreens and cosmetics. The effect is attributed to the generation of reactive oxygen species, as indicated by the inactivation enhancement observed in the presence of air.
Hancock-Chen
T
T
Department of Chemistry, University of Ottawa, Ont., Canada.
Scaiano
J C
JC
D052160:Benzothiazoles; D006735:Horseradish Peroxidase / Q000037:antagonists & inhibitors*; D017319:Photosensitizing Agents; D013451:Sulfonic Acids / Q000378:metabolism; D014025:Titanium; D014466:Ultraviolet Rays
D052160:Benzothiazoles; D017319:Photosensitizing Agents; D013451:Sulfonic Acids; C009495:titanium dioxide; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; D014025:Titanium; D006735:Horseradish Peroxidase