title: Comparison of the flow capacity of free arterial grafts and saphenous vein grafts for coronary bypass surgery.
abstract: There is controversy regarding the flow reserve and capacity of arterial conduits to meet the needs of the myocardium. This study compared flow in 22 free arterial bypasses to 15 saphenous vein grafts in procedures involving twenty patients. To assess the maximal flow possible, (flow capacity) graft flow was measured using a calibrated pump while perfusing blood cardioplegia through the conduit and distal anastomosis during cardiac arrest (no competitive flow). This assessment was subsequently confirmed with whole blood during myocardial contraction while on cardiopulmonary bypass. Twenty-two free arterial grafts were used; 15 right internal mammary artery grafts, 4 right gastroepiploic grafts, 3 inferior epigastric artery grafts, and 3 sequential bypasses. Free arterial conduit flow ranged from 50 to 180cc/ml, with an average flow of 102.5+/-28.5ml/min as compared to saphenous vein graft flow, 102+/-28 ml/min. No correlation of flow with the conduit size was found. Arterial graft flow demonstrated a mild correlation with the size of the native coronary artery bypassed (R=0.47, P</=0.02).
  
  
  CONCLUSIONS
  Basal flow through free arterial grafts is equivalent to saphenous vein grafts and is primarily determined by the native coronary vessels. The flow reserve for free arterial conduits is more than adequate for coronary bypass surgery.
authors.affiliation: University of California, San Francisco and The Robert Wood Johnson Medical School, USA. tshall@itsa.ucsf.edu
authors.forename: T S
authors.initials: TS
authors.lastname: Hall
authors.forename: J
authors.initials: J
authors.lastname: Ferguson
authors.forename: J
authors.initials: J
authors.lastname: Sines
authors.forename: A J
authors.initials: AJ
authors.lastname: Spotnitz
mesh_terms: D000328:Adult; D000368:Aged; D001158:Arteries / Q000637:transplantation*; D001026:Coronary Artery Bypass / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D012039:Regional Blood Flow; D012501:Saphenous Vein / Q000637:transplantation*