title: In vitro ear cartilage shaping with carbon dioxide laser: an experimental study.
abstract: Deformed cartilage remodeling appears to be a challenge, as cartilage tends to keep its initial shape because of internal stresses. Cartilage can be remodeled with heat, and this report describes the use of a CO2 laser beam for in vitro cartilaginous tissue remodeling. Straight cartilage samples were removed from the ears of 21 rabbits deprived of perichondrium and remodeled with the CO2 laser at an output power of 3 W, a spot diameter of 2 mm, and an exposure time of 0.5 second. The remodeled cartilages and control samples were implanted into the rabbits' backs and retrieved 6 to 12 months later. Histologic and morphological analysis showed that the irradiated cartilages retained both their shape and their viability. This may be a useful clinical technique for in situ remodeling of a deformed cartilage in operations such as septoplasty.
authors.affiliation: Department of Otolaryngology, University of Crete School of Medicine, Heraklion, Greece.
authors.forename: G A
authors.initials: GA
authors.lastname: Velegrakis
authors.forename: C E
authors.initials: CE
authors.lastname: Papadakis
authors.forename: A A
authors.initials: AA
authors.lastname: Nikolidakis
authors.forename: E P
authors.initials: EP
authors.lastname: Prokopakis
authors.forename: M E
authors.initials: ME
authors.lastname: Volitakis
authors.forename: I
authors.initials: I
authors.lastname: Naoumidi
authors.forename: E S
authors.initials: ES
authors.lastname: Helidonis
mesh_terms: D000818:Animals; D019902:Chondrocytes / Q000502:physiology / Q000648:ultrastructure; D004425:Ear Cartilage / Q000601:surgery* / Q000637:transplantation* / Q000648:ultrastructure; D053685:Laser Therapy / Q000379:methods*; D008854:Microscopy, Electron; D023421:Models, Animal; D011817:Rabbits; D012038:Regeneration / Q000502:physiology; D014182:Transplantation, Autologous / Q000379:methods