[Resistance and new antibiotic strategies. The problem with staphylococcus].
MRSA outside the hospital: From a major problem almost exclusively encountered in hospitalized patients, methicillin-resistant Staphylococcus aureus (MRSA) infection has become a cause of skin, soft tissue, and even systemic infections outside the hospital. In order to prevent further spread, patients carrying MRSA (recently hospitalized patients, drug abusers, debilitated subjects, etc) must be identified and the mode of acquisition of MRSA infection. (cross transmission between community and non-hospital care centers) must be recognized. Small colony variants: SCV produce non-pigmented colonies that are 10 times smaller than the usual S. aureus colonies and have particular metabolic and genetic properties. They can cause persistent, recurrent and drug-resistant infections. MRSA in France: Data obtained in a case-control study confirms the selection pressure as well as the important colonization pressure exerted by antibiotics on gentamicin-sensitive strains.
Bergoge-Bérézin
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D015169:Colony Count, Microbial; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000382:microbiology; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D005602:France / Q000453:epidemiology; D006801:Humans; D016106:Methicillin Resistance / Q000235:genetics / Q000502:physiology*; D010587:Phagocytosis; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics / Q000502:physiology