Appearance of peculiar vessels with immunohistological features of high endothelial venules in the dermis of moxibustion-stimulated rat skin.
Morphological changes of the dermal blood vessels ofmoxibustion-stimulated rat skin were examined with reference to the lymphocyte migration. After long-term stimulation with direct moxibustion to the acupoint tsu-san-li (St-36), peculiar vessels that possess immunohistological features of high endothelial venules could be observed in the moxa-stimulated acupoint dermis. Endothelial cells of the vessels had well-developed Golgi apparatus in their plump cytoplasms, and they strongly expressed intercellular adhesion molecule-1 on the luminal surface. These data suggest that the appearance of the peculiar vessels in the dermis acts toward the active infiltration of blood-lymphocytes into the acupoint skin.
Tohya
K
K
Department of Anatomy, Kansai College of Oriental Medicine, Sennan, Osaka, Japan.
Urabe
S
S
Igarashi
J
J
Tomura
T
T
Take
A
A
Kimura
M
M
D000818:Animals; D020405:Dermis / Q000098:blood supply* / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D004730:Endothelium, Vascular; D018799:Intercellular Adhesion Molecule-1 / Q000096:biosynthesis; D007509:Irritants / Q000009:adverse effects*; D008297:Male; D009071:Moxibustion / Q000009:adverse effects*; D051381:Rats; D017208:Rats, Wistar; D014699:Venules / Q000187:drug effects / Q000378:metabolism / Q000473:pathology
D007509:Irritants; D018799:Intercellular Adhesion Molecule-1