5,11-Epoxymegastigmanes from the leaves of Asclepias fruticosa).
Five new megastigmane glucosides and one of their aglycones were isolated, along with (6S,9R)-roseoside, from the polar fraction of the leaves of Asclepias fruticosa, and the structures were determined by spectroscopic methods. Most of them have an epoxy-linkage between C-5 and C-11. The configurations at C-3 and C-9 for each compound were confirmed to be S and R, respectively, by application of the modified Mosher's method.
Abe
F
F
Faculty of Pharmaceutical Sciences, Fukuoka University, Japan. abefumi@fukuoka-u.ac.jp
Yamauchi
T
T
D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry* / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D019684:Magnoliopsida / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry
D019086:Bridged Bicyclo Compounds, Heterocyclic; D005960:Glucosides