title: [Amniotic fluid leakage and premature rupture of membranes after amniocentesis. A review of the literature].
abstract: BACKGROUND
  Amniotic fluid leakage and premature rupture of membranes following amniocentesis is uncommon.
  
  
  METHODS
  We reviewed the literature. Thirteen recent studies including 17 186 amniocenteses and 280 cases of amniotic fluid leakage were analyzed.
  
  
  CONCLUSIONS
  Risk increases when early amniocentesis is performed prior to 15 weeks gestation and when the needle is inserted far from the placenta. Significant loss of amniotic fluid compromises pregnancy. Conservative management with bed rest seems to give good results. When amniotic leakage persists for more than two weeks, there is little spontaneous resolution. The risk of pursuing the pregnancy should be discussed with the couple in this case. Risks include respiratory disorders, skeletal malformations and premature birth.
  
  
  CONCLUSIONS
  New techniques such as 'amniopatch' may play an important role in the near future.
authors.affiliation: Service de Gynécologie Obstétrique, Centre Hospitalier Général, 02200 Soissons. pascalabboud@wanadoo.fr
authors.forename: P
authors.initials: P
authors.lastname: Abboud
authors.forename: A
authors.initials: A
authors.lastname: Zejli
authors.forename: G
authors.initials: G
authors.lastname: Mansour
authors.forename: Y
authors.initials: Y
authors.lastname: Monnoyer
authors.forename: L G
authors.initials: LG
authors.lastname: Houareau
authors.forename: H
authors.initials: H
authors.lastname: Bart
authors.forename: S
authors.initials: S
authors.lastname: Bock
mesh_terms: D000649:Amniocentesis / Q000009:adverse effects*; D000653:Amniotic Fluid; D001510:Bed Rest; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000209:etiology* / Q000628:therapy; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D012307:Risk Factors