Lymphoepithelioma-like carcinoma of the uterine cervix.
We describe two rare cervical tumors having morphologic features closely resembling those of the nasopharyngeal lymphoepithelioma. This entity has historically been classified as a subtype of squamous cell carcinoma, but after reviewing the literature and the two cases presented here, we propose that this tumor is a distinct carcinoma of the cervix that differs from squamous cell carcinoma in that it carries a more favorable prognosis, typically affects a younger population of women, is more prevalent in noncaucasian populations (especially those of Asian descent), and lacks a clearly defined association with infection due to human papilloma virus (HPV).
Skinner
N E
NE
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Horowitz
R I
RI
Majmudar
B
B
D001208:Asia / Q000208:ethnology; D001213:Asian; D002277:Carcinoma / Q000175:diagnosis / Q000208:ethnology / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000208:ethnology / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D014481:United States / Q000453:epidemiology; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000208:ethnology / Q000473:pathology*