A useful route to (R)- and (S)-tert-leucine.
Resolution of 1-(2-furyl)-2,2-dimethylpropylamine, an intermediate on a synthetic route to tert-leucine, followed by oxidation of the respective enantiomers, constitutes an interesting and useful strategy to (R)- and (S)-tert-leucine.
Allenmark
S
S
Department of Chemistry, Göteborg University, SE-14296 Göteborg, Sweden. stig.allenmark@oc.chalmers.se
Lamm
B
B
D007930:Leucine / Q000138:chemical synthesis* / Q000737:chemistry; D019906:Nuclear Magnetic Resonance, Biomolecular; D013237:Stereoisomerism
D007930:Leucine