Addition of casein or whey protein to colostrum or a colostrum supplement product on absorption of IgG in neonatal calves.
The effects of the addition of nonimmunoglobulin protein on absorption of immunoglobulin G (IgG) from colostrum or colostrum supplement products were determined in two experiments. In experiment 1, 48 Holstein calves were fed 4 L of pooled maternal colostrum or 4 L of reconstituted colostrum supplement with 0, 200, or 400 g of added whey protein concentrate or casein. In experiment 2, 38 Jersey calves were fed 2 L of pooled maternal colostrum with 100 or 200 g of whey protein concentrate or casein added immediately before feeding. Blood was collected at 24 h of age and plasma IgG concentration, total protein, hematocrit (experiment 1 only), and plasma urea N were determined. In experiment 1, blood samples were also collected at 4, 8, 12, 16, and 20 h to evaluate absorption of IgG and protein and urea N concentrations. The addition of 400 g of casein to colostrum supplement in experiment 1 reduced plasma IgG from 5.66 g/L (0 g of casein addition) to 3.88 g/L, increased plasma urea N at 24 h, and reduced the change in plasma total protein from 0 to 24 h. Hourly plasma IgG concentrations increased with the consumption of colostrum or supplements but increased more rapidly in calves fed whey protein concentrate and more slowly in calves fed casein. The addition of 200 g of casein or whey protein concentrate to colostrum supplements had no effect on plasma IgG concentration at 24 h of age. The addition of 100 or 200 g of casein or whey protein concentrate to maternal colostrum had no effect on plasma urea N, total protein, or plasma IgG in experiment 2. The addition of nonimmunoglobulin protein to colostrum supplements or maternal colostrum did not affect IgG absorption from the intestine of newborn calves unless the amount of total protein exceeded 500 g of protein.
Davenport
D F
DF
Institute of Agriculture, University of Tennessee, Knoxville 37901, USA.
Quigley
J D
JD
Martin
J E
JE
Holt
J A
JA
Arthington
J D
JD
D000818:Animals; D000831:Animals, Newborn / Q000276:immunology / Q000378:metabolism*; D002364:Caseins / Q000008:administration & dosage / Q000494:pharmacology*; D002417:Cattle / Q000276:immunology / Q000378:metabolism*; D003126:Colostrum / Q000276:immunology*; D005260:Female; D005526:Food, Formulated; D006400:Hematocrit / Q000662:veterinary; D007074:Immunoglobulin G / Q000097:blood / Q000378:metabolism*; D007408:Intestinal Absorption / Q000187:drug effects*; D007700:Kinetics; D008297:Male; D008894:Milk Proteins / Q000008:administration & dosage / Q000494:pharmacology*; D014508:Urea / Q000097:blood; D000067816:Whey Proteins
D002364:Caseins; D007074:Immunoglobulin G; D008894:Milk Proteins; D000067816:Whey Proteins; D014508:Urea