title: A novel synthetic methods for alpha-amino acids from allyl ethers via N-allylcarbamates.
abstract: Protected alpha-Phenyl glycine 17 and phenylalanine 18 and 19 have been synthesized through an efficient three-step sequence from the corresponding allyl ethers 5, 7, and 10. The key intermediate in this synthesis is the corresponding allylic amines prepared by reaction of allyl ethers with chlorosulfonyl isocyanate.
authors.affiliation: Laboratory of Organomedicinal Chemistry, College of Pharmacy, Sungkyunkwan University, Suwon, Korea. yhjung@skku.ac.kr
authors.forename: Y H
authors.initials: YH
authors.lastname: Jung
authors.forename: J D
authors.initials: JD
authors.lastname: Kim
mesh_terms: D000498:Allyl Compounds / Q000138:chemical synthesis*; D000596:Amino Acids / Q000138:chemical synthesis*; D002219:Carbamates / Q000138:chemical synthesis*; D004987:Ethers / Q000138:chemical synthesis*; D007202:Indicators and Reagents
chemical_list: D000498:Allyl Compounds; D000596:Amino Acids; D002219:Carbamates; D004987:Ethers; D007202:Indicators and Reagents