Fine-needle aspiration biopsy in the management of thyroid nodules in children and adolescents.
We reviewed the utility of fine-needle aspiration biopsy (FNAB) in the management of thyroid nodules in 41 children and adolescents (35 girls; mean age, 13.3 years). Cytologic findings were benign in 30, malignant in 2, suspicious in 6, and insufficient in 3. The malignancy rate was 5%, with no false-negative results. Diagnostic accuracy for FNAB was 87% and inter-observer reliability was 88%. FNAB is safe and highly accurate in the evaluation of thyroid nodules in childhood.
Al-Shaikh
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A
Department of Endocrinology, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.
Ngan
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B
Daneman
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A
Daneman
D
D
D000293:Adolescent; D000367:Age Factors; D001707:Biopsy, Needle / Q000592:standards*; D002648:Child; D002675:Child, Preschool; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D008297:Male; D015588:Observer Variation; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016606:Thyroid Nodule / Q000145:classification / Q000473:pathology* / Q000601:surgery