title: Diagnosis of a multifocal B cell lymphoma with preceding demyelinating central nervous system lesions by single voxel proton MR spectroscopy.
abstract: Single voxel proton magnetic resonance spectroscopy (MRS) provides a rapid non-invasive fingerprint of tissue chemistry. A case history is presented in which a B cell lymphoma with antecedent demyelinating lesions of the CNS was suspected by MRS and confirmed by neuropathological examination and immunoglobulin gene rearrangement.
authors.affiliation: Department of Neuropathology, Georg-August- University, Göttingen, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Kuhlmann
authors.forename: A
authors.initials: A
authors.lastname: Schröter
authors.forename: P
authors.initials: P
authors.lastname: Dechent
authors.forename: F
authors.initials: F
authors.lastname: Weber
authors.forename: H H
authors.initials: HH
authors.lastname: Rustenbeck
authors.forename: L
authors.initials: L
authors.lastname: Füzesi
authors.forename: W
authors.initials: W
authors.lastname: Brück
authors.forename: H
authors.initials: H
authors.lastname: Ehrenreich
authors.forename: J
authors.initials: J
authors.lastname: Frahm
mesh_terms: D000368:Aged; D002493:Central Nervous System Diseases / Q000175:diagnosis*; D003711:Demyelinating Diseases / Q000175:diagnosis*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D011522:Protons
chemical_list: D011522:Protons