title: A simplified technique for producing platelet-rich plasma and platelet concentrate for intraoral bone grafting techniques: a technical note.
abstract: A method to produce platelet-rich plasma and platelet concentrate using a double centrifuge technique in combination with the fibrin adhesive Tisseel is described. This technique constitutes the basic mixture for augmenting and improving an inadequate bone site. Also described is a procedure by which autologous bone or bone substitute is added to this mixture to increase the volume of grafting material. Platelet concentrates cause growth factors to be delivered to graft sites in an intense form, while Tisseel serves as a standardized, pharmaceutically manufactured fibrin adhesive.
authors.affiliation: Center for Dental Implants, Periodontology and Oral Surgery, Salzburg, Austria.
authors.forename: D
authors.initials: D
authors.lastname: Sonnleitner
authors.forename: P
authors.initials: P
authors.lastname: Huemer
authors.forename: D Y
authors.initials: DY
authors.lastname: Sullivan
mesh_terms: D000540:Alveolar Ridge Augmentation / Q000379:methods; D001792:Blood Platelets / Q000502:physiology*; D001804:Blood Transfusion, Autologous; D018786:Bone Substitutes / Q000627:therapeutic use; D016025:Bone Transplantation / Q000379:methods*; D002498:Centrifugation / Q000379:methods; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use; D006133:Growth Substances / Q000627:therapeutic use; D006801:Humans; D056948:Orthognathic Surgical Procedures; D017713:Platelet Transfusion / Q000379:methods*; D014014:Tissue Adhesives / Q000627:therapeutic use; D014182:Transplantation, Autologous
chemical_list: D018786:Bone Substitutes; D015718:Fibrin Tissue Adhesive; D006133:Growth Substances; D014014:Tissue Adhesives