Thiopentone induction dose requirement in dogs is little influenced by co-administration of diazepam or prior treatment with phenobarbitone or corticosteroids, but is reduced in the presence of brain pathology.
Dugdale
A H
AH
The Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, UK. alexd@liverpool.ac.uk
Lakhani
K H
KH
Brearley
J C
JC
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000771:Anesthesia, Intravenous / Q000662:veterinary*; D000818:Animals; D001927:Brain Diseases / Q000378:metabolism / Q000662:veterinary*; D003975:Diazepam / Q000008:administration & dosage; D004283:Dog Diseases / Q000378:metabolism*; D004285:Dogs / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006993:Hypnotics and Sedatives / Q000008:administration & dosage; D008297:Male; D010634:Phenobarbital / Q000008:administration & dosage; D013874:Thiopental / Q000008:administration & dosage* / Q000493:pharmacokinetics*
D000305:Adrenal Cortex Hormones; D006993:Hypnotics and Sedatives; D013874:Thiopental; D003975:Diazepam; D010634:Phenobarbital