[Diagnostic image (17). Acute dystonia induced by prochlorperazine].
An 11-year-old girl had a one-day history of nausea and vomiting for which her family physician prescribed 4 suppositories of prochlorperazine 25 mg. Five hours after the last dose she developed dystonic posturing; she recovered rapidly after intramuscular injection of 40 mg orphenadrine.
van Gijn
J
J
Universitair Medisch Centrum, afd. Neurologie, Heidelberglaan 100, 3584 CX Utrecht.
D000208:Acute Disease; D000932:Antiemetics / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D004409:Dyskinesia, Drug-Induced / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D009966:Orphenadrine / Q000627:therapeutic use; D011346:Prochlorperazine / Q000008:administration & dosage / Q000009:adverse effects*; D016896:Treatment Outcome; D014839:Vomiting / Q000188:drug therapy*
D000932:Antiemetics; D009125:Muscle Relaxants, Central; D009966:Orphenadrine; D011346:Prochlorperazine