Diagnosis of a multifocal B cell lymphoma with preceding demyelinating central nervous system lesions by single voxel proton MR spectroscopy.
Single voxel proton magnetic resonance spectroscopy (MRS) provides a rapid non-invasive fingerprint of tissue chemistry. A case history is presented in which a B cell lymphoma with antecedent demyelinating lesions of the CNS was suspected by MRS and confirmed by neuropathological examination and immunoglobulin gene rearrangement.
Kuhlmann
T
T
Department of Neuropathology, Georg-August- University, Göttingen, Germany.
Schröter
A
A
Dechent
P
P
Weber
F
F
Rustenbeck
H H
HH
Füzesi
L
L
Brück
W
W
Ehrenreich
H
H
Frahm
J
J
D000368:Aged; D002493:Central Nervous System Diseases / Q000175:diagnosis*; D003711:Demyelinating Diseases / Q000175:diagnosis*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D011522:Protons
D011522:Protons