title: A SADS defect in tumor cells provides optimism.
abstract: SADS, a new component of the Fas-mediated apoptotic pathway, is downregulated in patients with colon carcinoma. Could this downregulation be a widespread mechanism of tumor cell immune invasion?
authors.affiliation: Institute of Clinical Medicine and Research, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan. takahashi@jikei.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
mesh_terms: D017209:Apoptosis / Q000502:physiology; D003110:Colonic Neoplasms / Q000235:genetics* / Q000276:immunology / Q000473:pathology; D015536:Down-Regulation; D006801:Humans; D009363:Neoplasm Proteins / Q000235:genetics / Q000502:physiology*; D019014:fas Receptor / Q000502:physiology
chemical_list: D009363:Neoplasm Proteins; D019014:fas Receptor