[Lambing ewes as a source of severe psittacosis in a pregnant woman].
The first documented Dutch case of an ovine Chlamydia psittaci infection concerned a 20-year-old woman in the 26th week of pregnancy, following contact with lambing sheep. She had a severe sepsis and had to be artificially ventilated. Finally, the patient made a full recovery. The preterm born child died directly after birth. The placenta showed an acute intervillitis in which chlamydial antigen was demonstrated immunohistologically. Infection with an ovine C. psittaci was confirmed by sequence analysis of amplified chlamydial DNA from the placenta. Infections with C. psittaci are typically associated with contact with (sick) birds. However, mammals also may act as a source of human infection, especially sheep in which C. psittaci is an important cause of abortion. Infections with ovine C. psittaci are a particular hazard for pregnant women, in whom there is severe placentitis and frequently foetal loss. Such infections are mainly associated with contact with lambing sheep.
Kampinga
G A
GA
Afd. Medische Microbiologie, Academisch Ziekenhuis, Postbus 30.001, 9700 RB Groningen. g.a.kampinga@med.rug.nl
Schröder
F P
FP
Visser
I J
IJ
Anderson
J M
JM
Buxton
D
D
Möller
A V
AV
D000328:Adult; D000818:Animals; D023521:Chlamydophila Infections / Q000150:complications* / Q000635:transmission; D002691:Chlamydophila psittaci / Q000302:isolation & purification*; D004199:Disease Vectors; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010920:Placenta / Q000382:microbiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*; D011256:Pregnancy Outcome; D009956:Psittacosis / Q000635:transmission*; D012756:Sheep