title: Limb salvage in distal tibial osteosarcoma using a custom mega prosthesis.
abstract: We have assessed the oncological and functional results of limb salvage surgery using a custom-made endoprosthetic replacement in six patients (mean age 17 years) with distal tibial osteosarcoma (stage IIB). A wide margin excision was possible in three, marginal in two and contaminated in one. Skeletal reconstruction was performed using a locally designed and manufactured custom-made distal tibial and ankle replacement prosthesis. Two patients developed local recurrence and one necrosis of the flap and deep infection. In three in whom the prosthesis remained in place the mean functional score according to the rating system of the Musculoskeletal Tumour Society was 24.3/30. In carefully selected patients limb salvage with prosthetic replacement is possible for distal tibial osteosarcomas.
authors.affiliation: Madras Medical College and Research Institute, Chennai, India.
authors.forename: M V
authors.initials: MV
authors.lastname: Natarajan
authors.forename: K
authors.initials: K
authors.lastname: Annamalai
authors.forename: S
authors.initials: S
authors.lastname: Williams
authors.forename: R
authors.initials: R
authors.lastname: Selvaraj
authors.forename: T S
authors.initials: TS
authors.lastname: Rajagopal
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012516:Osteosarcoma / Q000175:diagnosis / Q000601:surgery*; D019736:Prostheses and Implants; D011474:Prosthesis Design; D013977:Tibia