title: Theory of cell membrane organizers and pressure reversal of anesthesia.
abstract: A theory of pressure reversal of anesthesia is proposed from a modern framework of condensed matter physics. A highly ordered cooperative dynamics of ordered water in the perimembranous region of nerve cells is analyzed, and the emergence of a new phase of condensation of massive photons in the perimembranous region is derived theoretically. The critical temperature of the massive photon condensation is estimated to be higher than the body temperature. The anesthetic molecules break the order of the ordered water condensation, and decrease the critical temperature of the emergent massive photon condensation there - a possible mechanism of anesthesia. Condensed matter physics tells that the critical temperature of the condensation phase is proportional to the pressure. The critical temperature of the massive photon condensation once decreased by the anesthetic molecules increases under the high pressure, restoring the order of the massive photon condensation, thus suggesting the pressure reversal of anesthesia.
authors.affiliation: Research Institute for Informatics and Science, Notre Dame Seishin University, Okayama, Japan. mariej@ndsu.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Jibu
mesh_terms: D000777:Anesthetics / Q000494:pharmacology*; D002462:Cell Membrane / Q000187:drug effects* / Q000648:ultrastructure; D004058:Diffusion; D008051:Lipid Bilayers; D017785:Photons
chemical_list: D000777:Anesthetics; D008051:Lipid Bilayers