title: Intellectual functioning and outcome of patients with severe psychotic illness randomised to intensive case management. Report from the UK700 trial.
abstract: BACKGROUND
  Little research has been carried out on the benefits of intensive case management (ICM) for people with borderline IQ and severe mental illness.
  
  
  OBJECTIVE
  To compare outcome and costs of care of patients with severe psychotic illness with borderline IQ to patients of normal IQ and to assess whether ICM is more beneficial for the former than for the latter.
  
  
  METHODS
  The study utilises data from the UK700 multi-centre randomised controlled trial of case management. The main outcome measure was the number of days spent in hospital for psychiatric reasons. Secondary outcomes were costs of care and clinical outcome.
  
  
  RESULTS
  ICM was significantly more beneficial for borderline-IQ patients than those of normal IQ in terms of reductions in days spent in hospital, hospital admissions, total costs and needs and increased satisfaction.
  
  
  CONCLUSIONS
  ICM appears to be a cost-effective strategy for a subgroup of patients with severe psychosis with cognitive deficits.
authors.affiliation: Department of Psychiatry and Behavioural Sciences, RF & UCMS, Wolfson Building, 48 Riding House Street, London W1N AA, UK. a.hassiotis@ucl.ac.uk
authors.forename: A
authors.initials: A
authors.lastname: Hassiotis
authors.forename: O C
authors.initials: OC
authors.lastname: Ukoumunne
authors.forename: S
authors.initials: S
authors.lastname: Byford
authors.forename: P
authors.initials: P
authors.lastname: Tyrer
authors.forename: K
authors.initials: K
authors.lastname: Harvey
authors.forename: J
authors.initials: J
authors.lastname: Piachaud
authors.forename: K
authors.initials: K
authors.lastname: Gilvarry
authors.forename: J
authors.initials: J
authors.lastname: Fraser
mesh_terms: D019090:Case Management / Q000458:organization & administration* / Q000592:standards; D003365:Costs and Cost Analysis; D004739:England; D006801:Humans; D007360:Intelligence / Q000502:physiology; D007398:Interpersonal Relations; D008605:Mental Health Services / Q000191:economics / Q000706:statistics & numerical data*; D010043:Outcome and Process Assessment, Health Care; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data; D019989:Persons with Intellectual Disabilities / Q000523:psychology*; D011379:Prognosis; D011618:Psychotic Disorders / Q000191:economics / Q000628:therapy*