Trisomy 7p: report of 2 patients and literature review.
Two patients with a trisomy 7p are reported. Both were assessed by facial dysmorphism and congenital anomalies. In one of the patients trisomy 7p was a de novo event, in the other patient unbalanced inheritance of a parental translocation caused trisomy 7p. Developmental delay was severe in both. Our 2 cases are compared with patients reported in literature.
Arens
Y H
YH
Department of Clinical Genetics, Academic Hospital Maastricht, The Netherlands.
Toutain
A
A
Engelen
J J
JJ
Offermans
J P
JP
Hamers
A J
AJ
Schrander
J J
JJ
Pulles-Heintzberger
C F
CF
Schrander-Stumpel
C T
CT
D000015:Abnormalities, Multiple / Q000235:genetics*; D002675:Child, Preschool; D002897:Chromosomes, Human, Pair 7; D020732:Cytogenetic Analysis; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D014314:Trisomy