title: Synthesis and antimycobacterial activity of some 4H-1,2,4-triazin-5-one derivatives.
abstract: 6-[(Arylmethylenamino)carbonyl]-3-(pyridin-2-yl)-4H-1,2,4-triazin-5-one derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed interesting activity against a strain of Mycobacterium tuberculosis.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università di Trieste, Italy. mamolo@univ.trieste.it
authors.forename: M G
authors.initials: MG
authors.lastname: Mamolo
authors.forename: V
authors.initials: V
authors.lastname: Falagiani
authors.forename: D
authors.initials: D
authors.lastname: Zampieri
authors.forename: L
authors.initials: L
authors.lastname: Vio
authors.forename: E
authors.initials: E
authors.lastname: Banfi
mesh_terms: D000995:Antitubercular Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D015394:Molecular Structure; D009162:Mycobacterium avium / Q000187:drug effects; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D014227:Triazines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000995:Antitubercular Agents; D014227:Triazines