[Evaluation of commercial equipment used in blood banks in Córdoba for the detection of anti-HTLV-I/II antibodies].
In order to assess the efficiency of currently used screening tests, Abbott HTLV-I/HTLV-II EIA, Vironostika HTLV-I/II Organon Teknika, Particle Agglutination (PA) assay Serodia Fujirebio Inc. (Tokyo, Japan) for HTLV-I/II antibody detection in blood donors samples, a panel of 100 sera from different blood banks of Córdoba city were studied. An "in house" indirect immunofluorescence assay (IFA) was used as reference test. The correlation rates were: 66% for Abbott HTLV-I/HTLV-II EIA, 97% for Vironostika HTLV-I/II Organon Teknika EIA and 99% for PA Serodia. Vironostika HTLV-I/II Organon Teknika EIA and PA Serodia assay proved to be more reliable for HTlV-I/II antibody screening in blood donors from Córdoba, yielding a very low rate of false positive results as compared with Abbot HTLV-I/HTLV-II EIA.
Llop
N
N
Instituto de Virología Dr. J. M. Vanella, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Avenida Valparaíso s/n, Ciudad Universitaria, 5016 Córdoba, Argentina.
Gastaldello
R
R
Valle
M
M
Macedo
R
R
Maturano
E
E
Blanco
S
S
Medeot
S
S
Gallego
S
S
D001118:Argentina; D001771:Blood Banks; D015481:HTLV-I Antibodies / Q000097:blood / Q000302:isolation & purification*; D015482:HTLV-II Antibodies / Q000097:blood / Q000302:isolation & purification*; D006801:Humans; D011933:Reagent Kits, Diagnostic / Q000592:standards*; D012680:Sensitivity and Specificity
D015481:HTLV-I Antibodies; D015482:HTLV-II Antibodies; D011933:Reagent Kits, Diagnostic