title: Identification and antimicrobial susceptibility of enterococci isolated from the root canal.
abstract: Enterococci are occurring in opportunistic infections involving the oral cavity. This study has identified enterococcal species in 29 endodontic infections undergoing treatment with Ca (OH)2 dressings. The in vitro antimicrobial susceptibility of 29 isolated enterococcal strains was determined. Enterococcus faecalis was speciated for 26 isolates and Enterococcus faecium for three isolates. In vitro antimicrobial susceptibility testing revealed enterococcal isolates resistant to benzylpenicillin, ampicillin, clindamycin, metronidazole and tetracycline but sensitive to erythromycin and vancomycin. Due to low sensitivity to antimicrobial agents, enterococci may be selected in root canals undergoing standard endodontic treatment and significantly contribute to endodontic treatment failures.
authors.affiliation: Department of Oral Microbiology, Faculty of Odontology, Göteborg University, Sweden.
authors.forename: G
authors.initials: G
authors.lastname: Dahlén
authors.forename: W
authors.initials: W
authors.lastname: Samuelsson
authors.forename: A
authors.initials: A
authors.lastname: Molander
authors.forename: C
authors.initials: C
authors.lastname: Reit
mesh_terms: D000667:Ampicillin / Q000627:therapeutic use; D000668:Ampicillin Resistance; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002126:Calcium Hydroxide / Q000627:therapeutic use; D002981:Clindamycin / Q000627:therapeutic use; D003786:Dental Pulp Cavity / Q000382:microbiology*; D003788:Dental Pulp Diseases / Q000188:drug therapy / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D013293:Enterococcus faecalis / Q000145:classification* / Q000187:drug effects; D016984:Enterococcus faecium / Q000145:classification* / Q000187:drug effects; D004917:Erythromycin / Q000627:therapeutic use; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use; D010400:Penicillin G / Q000627:therapeutic use; D010403:Penicillin Resistance; D010406:Penicillins / Q000627:therapeutic use; D012387:Root Canal Filling Materials; D013752:Tetracycline / Q000627:therapeutic use; D013753:Tetracycline Resistance; D017211:Treatment Failure; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D012387:Root Canal Filling Materials; D008795:Metronidazole; D002981:Clindamycin; D004917:Erythromycin; D014640:Vancomycin; D000667:Ampicillin; D013752:Tetracycline; D002126:Calcium Hydroxide; D010400:Penicillin G