Ovarian cryopreservation and transplantation: basic aspects.
Animal studies and studies using human ovarian xenografts in immunodeficient mice have shown that ovarian transplantation is feasible. In this manuscript, we present the first and limited experience with ovarian tissue cryopreservation and transplantation in the human. Despite the progress, more basic studies are needed to improve the survival of primordial follicles during and after the cryopreservation process.
Oktay
K
K
Department of Obstetrics and Gynecology, New York Methodist Hospital/Cornell University Weill Medical College, Brooklyn, NY 11215, USA.
Karlikaya
G G
GG
Aydin
B A
BA
D000818:Animals; D002986:Clinical Trials as Topic; D015925:Cryopreservation / Q000379:methods*; D005260:Female; D006801:Humans; D023421:Models, Animal; D010053:Ovary / Q000166:cytology / Q000637:transplantation*; D011247:Pregnancy; D014183:Transplantation, Heterologous