[Nitro derivatives: considerations on their antiplatelet activity].
The antischemic effect of nitrates is known and well accepted since more than 100 years, but recently many and interesting studies about antiaggregant property of such drugs have been reported. This action would be lied to increased synthesis of GMPc. The antiaggregant property pf nitrates may be leave open the problem to include the nitrates between the drugs able to influence the prognosis of myocardial infarction both in acute and chronic phase, such as betablockers, ASA and thrombolytics.
Carella
G
G
Università Cattolica del Sacro Cuore, Roma, Italia.
Mazzone
M
M
Burrai
I
I
Carbone
L
L
Siciliano
M
M
D003328:Coronary Thrombosis / Q000150:complications / Q000517:prevention & control; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy; D009566:Nitrates / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*
D009566:Nitrates; D010975:Platelet Aggregation Inhibitors