title: Thyroid carcinosarcoma, a rare and aggressive histotype: a case report.
abstract: Thyroid carcinosarcoma is a rare and aggressive thyroid tumor. Histological examination of a tumor showed the characteristic of epithelial carcinoma and mesenchymal differentiation. We retrospectively analyzed the course of the patient and reviewed the literature in which only 19 other cases are described. Carcinosarcoma of the thyroid is a very aggressive tumor with a clinical course similar to anaplastic thyroid carcinoma. Survival is very short despite aggressive multimodal treatment.
authors.affiliation: Department of Oncology, Ospedale S. Luigi-S. Currò, Catania, Italy. dariogiuffrida@netscape.net
authors.forename: D
authors.initials: D
authors.lastname: Giuffrida
authors.forename: M
authors.initials: M
authors.lastname: Attard
authors.forename: L
authors.initials: L
authors.lastname: Marasà
authors.forename: F
authors.initials: F
authors.lastname: Ferraù
authors.forename: F
authors.initials: F
authors.lastname: Marletta
authors.forename: N
authors.initials: N
authors.lastname: Restuccia
authors.forename: L
authors.initials: L
authors.lastname: Gambino
authors.forename: F
authors.initials: F
authors.lastname: Janni
authors.forename: G
authors.initials: G
authors.lastname: Failla
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use; D002296:Carcinosarcoma / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D015251:Epirubicin / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008197:Lymph Node Excision; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D013964:Thyroid Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D013965:Thyroidectomy
chemical_list: D000903:Antibiotics, Antineoplastic; D015251:Epirubicin