title: [Subacute sclerosing panencephalitis].
abstract: Subacute sclerosing panencephalitis is a slowly progressive neurodegenerative disorder occurring in childhood and adolescence and is characterised by dementia, ataxia, myoclonias and other neurological focal signs, with an invariably fatal outcome. The author reviews the subject, focussing on epidemiology, clinical features, measles virus behaviour, host immune reactions, measles prophylaxis and treatment proposals.
authors.affiliation: Unidade de Neurologia, Hospital de Dona Estefânia, Lisboa.
authors.forename: T
authors.initials: T
authors.lastname: Aguiar
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D005260:Female; D006801:Humans; D007542:Inosine Pranobex / Q000627:therapeutic use; D007372:Interferons / Q000627:therapeutic use; D008297:Male; D008457:Measles / Q000276:immunology / Q000821:virology; D008459:Measles virus / Q000276:immunology; D015995:Prevalence; D013344:Subacute Sclerosing Panencephalitis / Q000188:drug therapy / Q000453:epidemiology / Q000821:virology*
chemical_list: D000998:Antiviral Agents; D007372:Interferons; D007542:Inosine Pranobex