Successful use of propranolol in migraine associated with electroconvulsive therapy.
To date, there have been no reports on the use of propranolol in electroconvulsive therapy (ECT)-induced migraine; we describe a 32-year-old woman who was successfully treated with propranolol for this condition. Over a course of ECT, the patient developed increasingly severe migraine which was refractory to treatment with acetaminophen, codeine, and naproxen. Sumatriptan did not relieve the headache and aggravated the nausea. Successful migraine relief was achieved with a combination of propranolol and naproxen, administered before and after ECT. Propranolol reduced blood pressure and decreased the heart rate, measured before and immediately after ECT. Propranolol, possibly in combination with naproxen, may be useful in both acute and prophylactic treatment of post-ECT migraine.
Hawken
E R
ER
Kingston Psychiatric Hospital and the Department of Psychiatry, Queen's University, Kingston, Ontario K7L 3J7, Canada.
Delva
N J
NJ
Lawson
J S
JS
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D003863:Depression / Q000150:complications / Q000628:therapy; D004359:Drug Therapy, Combination; D004565:Electroconvulsive Therapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008881:Migraine Disorders / Q000150:complications / Q000188:drug therapy* / Q000209:etiology* / Q000517:prevention & control*; D009288:Naproxen / Q000008:administration & dosage / Q000627:therapeutic use*; D011292:Premedication; D011433:Propranolol / Q000008:administration & dosage / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D014665:Vasodilator Agents; D009288:Naproxen; D011433:Propranolol