A guide to 17beta-hydroxysteroid dehydrogenases.
17beta-Hydroxysteroid dehydrogenases (17beta-HSD) are pivotal in controlling the biological potency of steroid hormones by catalyzing oxidation or reduction at position 17. Several 17beta-HSDs may as well metabolize further substrates including alcohols, bile acids, fatty acids and retinols. This review summarizes recent progress in the field of 17beta-HSD research provides an update of nomenclature.
Adamski
J
J
GSF-National Research Center for Health and Environment, Institute for Experimental Genetics, Genome Analysis Center, Molecular Endocrinology and Proteomics Group, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
Jakob
F J
FJ
D015067:17-Hydroxysteroid Dehydrogenases / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D000818:Animals; D006801:Humans; D010084:Oxidation-Reduction; D013379:Substrate Specificity; D009626:Terminology as Topic
D015067:17-Hydroxysteroid Dehydrogenases