title: Protein interactions of fatty acid synthase II.
abstract: We have used a yeast two-hybrid approach to detect direct protein interactions between fatty acid synthase components. Enoyl-acyl carrier protein (ACP) reductase was found to interact with stearoyl-ACP desaturase and acyl-ACP thioesterase, but none of these proteins interacted with ACP in the yeast nucleus.
authors.affiliation: Department of Biological Sciences, University of Durham, South Road, Durham DH1 3LE, UK.
authors.forename: G
authors.initials: G
authors.lastname: Honeyman
authors.forename: T
authors.initials: T
authors.lastname: Fawcett
mesh_terms: D002467:Cell Nucleus / Q000201:enzymology* / Q000235:genetics; D050753:Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); D064429:Fatty Acid Synthases / Q000378:metabolism*; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D010088:Oxidoreductases / Q000378:metabolism*; D011994:Recombinant Proteins / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000201:enzymology; D013869:Thiolester Hydrolases / Q000378:metabolism*
chemical_list: D011994:Recombinant Proteins; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; C018747:acyl-(acyl-carrier-protein)desaturase; D050753:Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); D064429:Fatty Acid Synthases; D013869:Thiolester Hydrolases; C018748:oleoyl-(acyl-carrier-protein) hydrolase