title: Basilar artery thrombosis in a child heterozygous for factor V Leiden mutation.
abstract: Activated protein C resistance, usually because of factor V Leiden mutation, is considered to be the most common hereditary prothrombotic condition. A 9-year-old male with a basilar artery stroke and activated protein C resistance is described. The patient, found to be heterozygous for factor V Leiden mutation, is one of several recent reports that suggest that activated protein C resistance is an important risk factor for spontaneous arterial thrombosis in infancy and childhood.
authors.affiliation: Pediatric Neurology Unit, Hospital Virgen de la Salud, Toledo, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Verdú
authors.forename: M R
authors.initials: MR
authors.lastname: Cazorla
authors.forename: M A
authors.initials: MA
authors.lastname: Granados
authors.forename: J A
authors.initials: JA
authors.lastname: Alonso
authors.forename: L F
authors.initials: LF
authors.lastname: Casado
mesh_terms: D020016:Activated Protein C Resistance / Q000175:diagnosis / Q000235:genetics*; D001488:Basilar Artery / Q000473:pathology; D002533:Cerebral Angiography; D002648:Child; D005165:Factor V / Q000235:genetics*; D006580:Genetic Carrier Screening; D006801:Humans; D020766:Intracranial Embolism / Q000175:diagnosis / Q000235:genetics*; D008279:Magnetic Resonance Imaging; D008297:Male
chemical_list: C095381:factor V Leiden; D005165:Factor V