title: Enantio- and diastereoselective michael reactions of silyl enol ethers and chalcones by catalysis using a chiral quaternary ammonium salt.
abstract: [reaction: see text] N-(9-Anthracenylmethyl)dihydrocinchonidinium bromide (1) is an effective catalyst for enantioselective Michael additions to chalcones, as shown in the above example, using toluene/50% aqueous KOH biphasic conditions at -20 degrees C.
authors.affiliation: Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
authors.forename: F
authors.initials: F
authors.lastname: Zhang
authors.forename: E J
authors.initials: EJ
authors.lastname: Corey