title: Post-thyroidectomy hypocalcemia and feasibility of short-stay thyroid surgery.
abstract: OBJECTIVE
  To study the feasibility of thyroid surgery in a short-stay hospitalization regimen, with particular reference to postoperative hypocalcemia.
  
  
  METHODS
  The clinical files of 696 patients operated on from January 1977 to January 2000 for thyroid diseases were analyzed. They were divided into groups on the basis of extent of operation and type of disease. Hypocalcemia incidence was compared between the different groups of patients. Data were analyzed statistically using the chi-square and Fisher's exact tests.
  
  
  RESULTS
  There were 74 temporary (10.6%) and 12 (1.7%) persistent hypocalcemia cases. None of these occurred in patients undergoing lobectomy. The incidence of hypocalcemia was higher in two-lobe vs. single-lobe operations (p < 0.05), in total thyroidectomy with lymphadenectomy vs. total thyroidectomy (p < 0.05) and in hyperthyroidism vs. patients with normal serum hormone levels (p < 0.05). 84.9% of hypocalcemia cases developed on postoperative day 1, with only one tetanic crisis.
  
  
  CONCLUSIONS
  Thyroid surgery in the short-stay hospitalization regimen is feasible for all patients undergoing lobectomy. Patients undergoing subtotal or total thyroidectomy may be treated in a short-stay regimen, only if they are affected with non-hyperfunctioning benign diseases and if they have normal serum calcium levels on postoperative day 1.
authors.affiliation: Second Department of General Surgery, Post-graduate School of Thoracic Surgery, Milan.
authors.forename: L
authors.initials: L
authors.lastname: De Pasquale
authors.forename: L
authors.initials: L
authors.lastname: Schubert
authors.forename: A
authors.initials: A
authors.lastname: Bastagli
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000453:epidemiology* / Q000209:etiology*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013965:Thyroidectomy / Q000009:adverse effects*