title: Failure of endovascular abdominal aortic aneurysm graft limbs.
abstract: OBJECTIVE
  Endovascular abdominal aortic aneurysm (AAA) grafts are subject to subsequent failure of endograft limbs. We sought to determine what device-related factors could be identified that might contribute to limb failure.
  
  
  METHODS
  We reviewed the records of patients who had undergone endovascular AAA repair and femorofemoral bypass grafting at a single institution.
  
  
  RESULTS
  Endovascular AAA repair was performed in 173 patients. There were 137 bifurcated endografts and 36 aortomonoiliac grafts combined with femorofemoral bypass grafts, yielding a total population of 310 aortic graft limbs and 36 femorofemoral grafts. Thirty-nine additional patients underwent femorofemoral bypass grafting for occlusive disease. The cumulative primary patency of all endografts performed for AAA was 92% at 21 months. Secondary patency was achieved for all failed endograft limbs. There were 24 aortic graft limb "failures" that required intervention: seven limbs underwent thrombosis requiring revision; kinked limbs requiring stenting either at the time of graft placement (17) or subsequently (7) were identified. Fully supported endograft limbs had better primary patency (97% at 18 months) than unsupported limbs (69% at 18 months, P <.001). The aortomonoiliac grafts with femorofemoral bypass grafts tended to have better patency (97% at 18 months) than bifurcated endografts (90% at 18 months), but this did not reach statistical significance (P =.28, not significant). Femorofemoral grafts performed for occlusive disease were found to have somewhat lower patency than those performed for AAA (83% vs 92% at 18 months of follow-up, P =.37, not significant).
  
  
  CONCLUSIONS
  Fully supported AAA endografts provide superior endograft limb patency compared with unsupported designs. Consideration should be given to routine stenting of all unsupported endograft limbs. Aortomonoiliac grafts and bifurcated grafts provide similar results for endograft limb patency. Femorofemoral bypass grafts performed in conjunction with aortomonoiliac grafts for AAA disease provide excellent short-term patency.
authors.affiliation: Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, USA. jpcarp@mail.med.upenn.edu
authors.forename: J P
authors.initials: JP
authors.lastname: Carpenter
authors.forename: D G
authors.initials: DG
authors.lastname: Neschis
authors.forename: R M
authors.initials: RM
authors.lastname: Fairman
authors.forename: C F
authors.initials: CF
authors.lastname: Barker
authors.forename: M A
authors.initials: MA
authors.lastname: Golden
authors.forename: O C
authors.initials: OC
authors.lastname: Velazquez
authors.forename: M E
authors.initials: ME
authors.lastname: Mitchell
authors.forename: R A
authors.initials: RA
authors.lastname: Baum
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001012:Aorta, Abdominal / Q000601:surgery; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects; D005260:Female; D005263:Femoral Artery / Q000601:surgery; D006083:Graft Occlusion, Vascular / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007083:Iliac Artery / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D011474:Prosthesis Design; D011859:Radiography; D012189:Retrospective Studies; D015607:Stents / Q000009:adverse effects; D013927:Thrombosis / Q000175:diagnosis / Q000628:therapy; D014654:Vascular Patency
chemical_list: D011138:Polytetrafluoroethylene