title: Choroid plexus papilloma with osseous and adipose metaplasia.
abstract: Rare cases of osseous and chondroid metaplasia in choroid plexus papillomas have been described. We report a case of left lateral ventricular choroid plexus papilloma presenting in a 25-year-old man. The tumor demonstrates prominent calcification with associated osseous metaplasia and a region of adipose metaplasia, which has not been previously described in these tumors. There is no evidence of mucin in the papilloma on mucicarmine and alcian blue stains. A MIB-1 labeling index (marker of cell proliferation) of 0.1% was noted. P53 immunoreactivity was not observed in the papilloma. Ann Diagn Pathol 5:43-47, 2001.
authors.affiliation: Department Pathology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
authors.forename: G M
authors.initials: GM
authors.lastname: Corcoran
authors.forename: S R
authors.initials: SR
authors.lastname: Frazier
authors.forename: R A
authors.initials: RA
authors.lastname: Prayson
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry / Q000473:pathology*; D000328:Adult; D034961:Antigens, Nuclear; D001842:Bone and Bones / Q000737:chemistry / Q000473:pathology*; D002455:Cell Division; D016545:Choroid Plexus Neoplasms / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D019394:Ki-67 Antigen; D008279:Magnetic Resonance Imaging; D008297:Male; D008679:Metaplasia / Q000473:pathology; D009687:Nuclear Proteins / Q000032:analysis; D010212:Papilloma / Q000737:chemistry / Q000473:pathology*; D016159:Tumor Suppressor Protein p53 / Q000032:analysis
chemical_list: D034961:Antigens, Nuclear; D019394:Ki-67 Antigen; D009687:Nuclear Proteins; D016159:Tumor Suppressor Protein p53