title: "Congo" red: out of Africa?
abstract: BACKGROUND
  Congo red is the essential histologic stain for demonstrating the presence of amyloidosis in fixed tissues. To the best of my knowledge, nothing has been written about why the stain is named "Congo."
  
  
  OBJECTIVE
  To understand the etymology and history of the Congo red histologic stain.
  
  
  METHODS
  Primary sources were consulted extensively, including 19th-century corporate documents, newspapers, legal briefs, patents, memoirs, and scientific papers.
  
  
  METHODS
  Sources were obtained from multiple university libraries and German corporate archives.
  
  
  RESULTS
  To Europeans in 1885, the word Congo evoked exotic images of far-off central Africa known as The Dark Continent. The African Congo was also a political flashpoint during the Age of Colonialism. "Congo" red was introduced in Berlin in 1885 as the first of the economically lucrative direct textile dyes. A patent on Congo red was filed by the AGFA Corporation of Berlin 3 weeks after the conclusion of the well-publicized Berlin West Africa Conference. During these important diplomatic talks, German Chancellor Otto von Bismarck presided over a discussion of free trade issues in the Congo River basin. A challenge to AGFA's Congo red patent led to a precedent-setting decision in intellectual property law.
  
  
  CONCLUSIONS
  The Congo red stain was named "Congo" for marketing purposes by a German textile dyestuff company in 1885, reflecting geopolitical current events of that time.
authors.affiliation: Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA. steensma.david@mayo.edu
authors.forename: D P
authors.initials: DP
authors.lastname: Steensma
mesh_terms: D000349:Africa; D000682:Amyloid / Q000032:analysis; D000686:Amyloidosis / Q000175:diagnosis / Q000266:history; D002617:Chemical Industry / Q000266:history; D004396:Coloring Agents / Q000266:history*; D003223:Congo; D003224:Congo Red / Q000266:history*; D005858:Germany; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D006863:Hydrogen-Ion Concentration; D013784:Textiles / Q000266:history
chemical_list: D000682:Amyloid; D004396:Coloring Agents; D003224:Congo Red