title: Positive response to immunomodulatory therapy in an adult patient with Rasmussen's encephalitis.
abstract: Rasmussen's encephalitis (RE) is a rare and progressive neurologic condition of uncertain etiology that typically has a childhood onset. The authors describe a 45-year-old woman with adult-onset progressive aphasia, right hemiparesis, severe drug refractory epilepsy, and left cerebral hemisphere atrophy. High-dose corticosteroids and plasmapheresis were not effective. She improved with high-dose therapy with human IV immunoglobulin.
authors.affiliation: Division of Clinical Neurophysiology and Epileptology, Istituto Nazionale Neurologico "C. Besta," Milan, Italy. neurofisiologia@istituto-besta.it
authors.forename: F
authors.initials: F
authors.lastname: Villani
authors.forename: R
authors.initials: R
authors.lastname: Spreafico
authors.forename: L
authors.initials: L
authors.lastname: Farina
authors.forename: A R
authors.initials: AR
authors.lastname: Giovagnoli
authors.forename: P
authors.initials: P
authors.lastname: Bernasconi
authors.forename: T
authors.initials: T
authors.lastname: Granata
authors.forename: G
authors.initials: G
authors.lastname: Avanzini
mesh_terms: D001921:Brain / Q000473:pathology; D004660:Encephalitis / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged
chemical_list: D016756:Immunoglobulins, Intravenous