title: Polymorphism in regulatory gene sequences.
abstract: The extensive polymorphism revealed in non-coding gene-regulatory sequences, particularly in the immune system, suggests that this type of genetic variation is functionally and evolutionarily far more important than has been suspected, and provides a lead to new therapeutic strategies.
authors.affiliation: Department of Immunology, Windeyer Institute of Medical Science, University College London Medical School, Cleveland Street, London W1P 6DB, UK. n.mitchison@ucl.ac.uk
authors.forename: N A
authors.initials: NA
authors.lastname: Mitchison
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D020022:Genetic Predisposition to Disease / Q000235:genetics; D014644:Genetic Variation; D006801:Humans; D008285:Major Histocompatibility Complex / Q000235:genetics; D011110:Polymorphism, Genetic; D012045:Regulatory Sequences, Nucleic Acid / Q000235:genetics*