[The effects of BDP on eosinophils in nasal secretions of the patient with allergic rhinilis].
The effects of beclomethasone dipropionate (BDP) on eosinophils in nasal secretions of the patients with allergic rhinilis was assaied under the laser scanning confocal microscopy and the technology of fluoresence. The scanning images displayed that fluoresence signal of the eosinophils intracellular RNA was significantly decreased after BDP treatment. The results showed that anti-inflammation funtion of BDP was realized by controlling the intracellular DNA translate to RNA.
Lin
J
J
Shantou University Medical College, Shantou 515031.
Shen
Z
Z
Chen
Y
Y
D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001507:Beclomethasone / Q000494:pharmacology*; D002469:Cell Separation; D004804:Eosinophils / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D018613:Microscopy, Confocal; D009296:Nasal Cavity / Q000473:pathology; D012313:RNA / Q000378:metabolism; D012221:Rhinitis, Allergic, Perennial / Q000473:pathology*
D000893:Anti-Inflammatory Agents; D012313:RNA; D001507:Beclomethasone