Does massively parallel transcriptome analysis signify the end of cancer histopathology as we know it?
Transcriptional analysis of all the genes expressed by breast tumors has provided the first steps towards defining a molecular signature for the disease, and might ultimately make conventional diagnostic techniques obsolete.
Aparicio
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SA
Department of Oncology, University of Cambridge, Wellcome Trust/MRC Building, Addenbrookes Hospital, Cambridge CB2 2XY,UK. saparici@hgmp.mrc.ac.uk
Caldas
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Ponder
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D014408:Biomarkers, Tumor / Q000235:genetics; D001943:Breast Neoplasms / Q000145:classification / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology*; D020224:Expressed Sequence Tags; D020869:Gene Expression Profiling / Q000639:trends; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D009367:Neoplasm Staging; D020411:Oligonucleotide Array Sequence Analysis / Q000639:trends; D012334:RNA, Neoplasm / Q000032:analysis / Q000235:genetics
D014408:Biomarkers, Tumor; D012334:RNA, Neoplasm