title: nm23-H1 Expression in Squamous Cell Carcinoma of the Head and Neck.
abstract: Archival material from 47 patients with primary squamous cell carcinoma of the head and neck (SCCHN) was studied immunohistochemically for the presence of nm23-H1 protein. Our data indicate that nm23-H1 protein expression is a common event in SCCHN and that there is a trend toward correlation of increased expression of nm23-H1 with increasing tumor size (p = 0.072). The results also show that when adjusting for age and cause of death, there tended to be an inverse relationship between overall survival and the expression of nm23-H1 gene in the primary tumor (p = 0.088).
authors.affiliation: University of Cincinnati College of Medicine, Department of Otolaryngology-Head and Neck Surgery, Cincinnati, USA.
authors.forename: John S
authors.initials: JS
authors.lastname: McDonald
authors.forename: Peter S
authors.initials: PS
authors.lastname: Gartside
authors.forename: Ljiljana J
authors.initials: LJ
authors.lastname: Pavelic
authors.forename: Jack L
authors.initials: JL
authors.lastname: Gluckman
authors.forename: Zlatko P
authors.initials: ZP
authors.lastname: Pavelic