[Acute leukemia in the elderly patient. Forty case reports].
Between 1989 and 1996, 40 cases with acute leukemia (16 males and 24 females) were diagnosed in our institution. Median age was 65 years (range, 56-88 years). Leukocyte count was more than 30.109/l in 42% of cases. According to the French-American-British (FAB) criteria, 11 cases were classified lymphoblastic and 29 myeloblastic. Sixteen patients have received palliative treatment because of there age and there bad performance status. Only 24 patients have received curative treatment. Complete remission was achieved in 12 cases (50%), 5 cases (20%) failed to respond and 7 (30%) died during induction. Relapse was observed in 8 cases. The 2-year survival rate was 10% confirming the worse prognosis of the acute leukemia in elderly.
Laatiri
M A
MA
Service d'Hématologie Clinique, CHU Farhat Hached de Sousse, Tunisie.
Chehata
S
S
Ajmi
F
F
Amouri
A
A
Bouaouina
N
N
Saad
A
A
Ennabli
S
S
D000206:Actuarial Analysis; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D011379:Prognosis; D012074:Remission Induction; D012189:Retrospective Studies; D017678:Sex Distribution; D016019:Survival Analysis; D016896:Treatment Outcome; D014416:Tunisia / Q000453:epidemiology