Probing the interface between membrane proteins and membrane lipids by X-ray crystallography.
Biological membranes are composed of a complex mixture of lipids and proteins, and the membrane lipids support several key biophysical functions, in addition to their obvious structural role. Recent results from X-ray crystallography are shedding new light on the precise molecular details of the protein-lipid interface.
Fyfe
P K
PK
Dept of Biochemistry, University of Bristol, BS8 1TD, Bristol, UK.
McAuley
K E
KE
Roszak
A W
AW
Isaacs
N W
NW
Cogdell
R J
RJ
Jones
M R
MR
D001436:Bacteriorhodopsins / Q000737:chemistry; D002308:Cardiolipins / Q000737:chemistry; D002462:Cell Membrane / Q000737:chemistry* / Q000378:metabolism; D018360:Crystallography, X-Ray / Q000379:methods*; D003576:Electron Transport Complex IV / Q000737:chemistry; D050356:Lipid Metabolism; D008055:Lipids / Q000737:chemistry*; D008958:Models, Molecular; D045322:Photosynthetic Reaction Center Complex Proteins / Q000737:chemistry
D002308:Cardiolipins; D008055:Lipids; D045322:Photosynthetic Reaction Center Complex Proteins; D001436:Bacteriorhodopsins; D003576:Electron Transport Complex IV