Improving the catalytic performance of peroxidases in organic synthesis.
Peroxidases are ubiquitous enzymes that catalyze a variety of enantioselective oxygen-transfer reactions with hydrogen peroxide (H2O2). Although they have enormous potential, their industrial application is hampered by their high price and low operational stability. Recent developments, such as the controlled addition and in situ formation of the oxidant, protein engineering and the rational design of semi-synthetic peroxidases, aim to improve the operational stability of peroxidases.
van de Velde
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Nizo Food Research, PO Box 20, 6710 BA, Ede, The Netherlands.
van Rantwijk
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Sheldon
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D002384:Catalysis; D006861:Hydrogen Peroxide / Q000378:metabolism; D010544:Peroxidases / Q000378:metabolism*; D015202:Protein Engineering
D006861:Hydrogen Peroxide; D010544:Peroxidases