title: The size of the fetal thoracolumbar spine: a three-dimensional ultrasound study.
abstract: OBJECTIVE
  To evaluate three-dimensional sonographic measurements of the thoracolumbar spine in the 16-37 week fetus.
  
  
  METHODS
  Prospective cross-sectional study.
  
  
  METHODS
  Two hundred and eighty-nine patients between 16 and 37 weeks of gestation were enrolled at the time of their anomaly scan or routine third trimester scan if fetal size was appropriate for gestational age and if no fetal anomalies were apparent.
  
  
  METHODS
  Three-dimensional (3D) volume calculation of the first and fifth lumbar vertebral body, the 12th thoracic vertebral body and the whole lumbar spine was performed in the transverse plane of the multiplanar mode while lumbar spine length was determined in the sagittal plane.
  
  
  RESULTS
  All volumetric measurements were significantly correlated with gestational age and estimated fetal weight. For each examined parameter regression analysis was performed to describe the 'best-fit' equation.
  
  
  CONCLUSIONS
  3D sonography allows volume calculation of the fetal spine. Our study provides further data relating to volume changes in the developing fetal spine between 16 and 37 weeks of gestation.
authors.affiliation: Department of Prenatal Diagnosis and Therapy, Centre for Obstetrics and Gynaecology, University Hospital Bonn, Germany.
authors.forename: R L
authors.initials: RL
authors.lastname: Schild
authors.forename: T
authors.initials: T
authors.lastname: Wallny
authors.forename: R
authors.initials: R
authors.lastname: Fimmers
authors.forename: M
authors.initials: M
authors.lastname: Hansmann
mesh_terms: D003430:Cross-Sectional Studies; D005314:Embryonic and Fetal Development / Q000502:physiology; D005260:Female; D020567:Fetal Weight; D005865:Gestational Age; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging* / Q000196:embryology*; D011237:Predictive Value of Tests; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011446:Prospective Studies; D012044:Regression Analysis; D012680:Sensitivity and Specificity; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging* / Q000196:embryology*; D016216:Ultrasonography, Prenatal / Q000379:methods*