Passive antibody to Bartonella henselae protects against clinical disease following homologous challenge but does not prevent bacteremia in cats.
We challenged cats transfused with anti-Bartonella serum and kittens born to antibody-positive queens with Bartonella henselae to determine the contribution of antibodies to the control of B. henselae in cats. In both experiments, antibody-positive cats were protected from clinical disease but passive antibody to the homologous strain of B. henselae did not prevent bacteremia.
O'Reilly
K L
KL
Department of Veterinary Microbiology and Parasitology, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, USA. oreilly@mail.vetmed.lsu.edu
Parr
K A
KA
Brown
T P
TP
Tedder-Ferguson
B
B
Scholl
D T
DT
D000818:Animals; D000907:Antibodies, Bacterial / Q000627:therapeutic use*; D016470:Bacteremia / Q000517:prevention & control*; D018416:Bartonella henselae / Q000276:immunology*; D002372:Cat-Scratch Disease / Q000517:prevention & control*; D002415:Cats; D005260:Female; D007116:Immunization, Passive
D000907:Antibodies, Bacterial