title: Risk factors for leg wound complications following endoscopic versus traditional saphenous vein harvesting.
abstract: BACKGROUND
  Risk factors for leg wound complications following traditional saphenectomy have included: obesity, diabetes, female gender, anemia, age, and peripheral vascular disease. Use of an endoscopic saphenectomy technique may modify the risk factor profile associated with a traditional longitudinal incision.
  
  
  METHODS
  From September 1996 to May 1999, 276 consecutive patients who underwent elective isolated coronary artery bypass grafting performed by a single surgeon (K.B.A.) had their greater saphenous vein harvested endoscopically. During the period from January 1999 to May 1999, the surgical records of 643 patients who underwent the same operation and had a traditional longitudinal saphenectomy were reviewed for postoperative leg wound complications. Group demographics were similar regarding preoperative risk stratification and traditionally identified wound complication risk factors (diabetes, gender, obesity, preoperative anemia, and peripheral vascular disease). Leg wound complications were defined as: hematoma, dehiscence, cellulitis, necrosis, or abscess requiring dressing changes, antibiotics and/or debridement prior to complete epithelialization. Follow-up was 100% at six weeks.
  
  
  RESULTS
  Leg wound complications following endoscopic harvest occurred in 3% (9/276) of patients versus 17% (110/643) of traditional harvest patients (p < 0.0001). No univariate risk factors for wound complications were associated with endoscopic saphenectomy. Univariate predictors of wound complications following traditional saphenectomy included: diabetes (p = 0.001), obesity (p = 0.0005), and female gender (p = 0.005). Multivariable risk factors for leg wound complications following saphenectomy were traditional harvest technique (OR 7.56, CI 3.8-17.2, p < 0.0001), diabetes (OR 2.10, CI 1.4-3.2, p = 0.0006) and obesity (OR 1.82, CI 1.2-2.8, p = 0.007).
  
  
  CONCLUSIONS
  Traditional longitudinal saphenectomy is a multivariable risk factor for development of leg wound complications. Endoscopic saphenectomy modifies the risk factor profile for wound complications and should be the standard of care, particularly for obese and/or diabetic patients who require venous conduit during coronary artery bypass grafting.
authors.affiliation: Indiana Heart Institute, St. Vincent Hospital and Health Care Center, Indianapolis, USA. cshaar@iquest.net
authors.forename: K B
authors.initials: KB
authors.lastname: Allen
authors.forename: D A
authors.initials: DA
authors.lastname: Heimansohn
authors.forename: R J
authors.initials: RJ
authors.lastname: Robison
authors.forename: J J
authors.initials: JJ
authors.lastname: Schier
authors.forename: G L
authors.initials: GL
authors.lastname: Griffith
authors.forename: E B
authors.initials: EB
authors.lastname: Fitzgerald
authors.forename: J H
authors.initials: JH
authors.lastname: Isch
authors.forename: S
authors.initials: S
authors.lastname: Abraham
authors.forename: C J
authors.initials: CJ
authors.lastname: Shaar
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D016001:Confidence Intervals; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000379:methods*; D003327:Coronary Disease / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D048909:Diabetes Complications; D004724:Endoscopy / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007866:Leg; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000009:adverse effects / Q000379:methods; D009767:Obesity, Morbid / Q000150:complications; D016017:Odds Ratio; D011336:Probability; D012189:Retrospective Studies; D012307:Risk Factors; D012501:Saphenous Vein / Q000637:transplantation*; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000209:etiology*; D020858:Tissue and Organ Harvesting / Q000009:adverse effects* / Q000379:methods*