[Persistent hyperinsulinemic hypoglycemia (PHHI)--surgical management of neonatal hypoglycemia].
Sporadic persistent hyperinsulinemic hypoglycaemia in a newborn is a rare disease which requires early surgical treatment if conservative therapy fails. We report on a newborn female in whom PHHI was diagnosed at the second day of life. She presented with severe hypoglycemia and high levels of plasma insulin. Conservative treatment failed and a near-total pancreatectomy was performed on the 24th day of life. The postoperative outcome and the follow-up studies showed the patient to be euglycaemic. If hypoglycaemia is resistant to conservative therapy, surgical treatment is recommended. A loss of pancreatic exocrine function is not necessarily to be expected.
Pomberger
G
G
Klinische Abteilung für Kinderchirurgie, Universitätsklinik für Chirurgie, Osterreich.
Hallwirth
U
U
Kirchner
L
L
Horcher
E
E
D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D005951:Glucose Tolerance Test; D006801:Humans; D006946:Hyperinsulinism / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D007003:Hypoglycemia / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D007223:Infant; D007231:Infant, Newborn; D010179:Pancreas / Q000473:pathology; D010180:Pancreatectomy; D010182:Pancreatic Diseases / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D010186:Pancreatic Function Tests; D011183:Postoperative Complications / Q000175:diagnosis