[Integration of orbitary polyethilene implants (MEDPOR). Histologic study].
OBJECTIVE
We study the histological integration of high-density porous polyethylene orbital implants and its clinical meaning.


METHODS
During the last 16 months we have used 14 implants of MEDPOR. Two were removed because of migration, the first one and partial extrusion, the second one, after 3 and 9 months since implantation, respectively. They were preserved and softened in formaldehyde for one month, and later processed for histological study.


RESULTS
Macroscopically, a fibrous pseudocapsule firmly attached to the implant was seen. A fibrovascular tissue ingrowth covered the polyethylene porous surface and penetrated its total cross-sectional area. Occasional inflammatory cells were present. There was no evidence of macrophagical activity.


CONCLUSIONS
We demonstrate a good fibrovascular integration of the implant at the time of extraction. This means that this material can be successfully used in anophthalmic socket surgery. However, new pathological and clinical studies are necessary to elucidate their biocompatibility in long follow-up time.
Núñez Sánchez
A
A
Hospital Ramón y Cajal, Madrid, España.
Reche Sainz
J A
JA
Sanz López
A
A
Mateos Sánchez
E
E
García Llanes
G
G
San Miguel Fraile
P
P
Fernández Escámez
C S
CS
D000328:Adult; D001672:Biocompatible Materials; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000473:pathology; D020273:Orbital Implants; D011095:Polyethylenes
D001672:Biocompatible Materials; C084562:Medpor; D011095:Polyethylenes