title: [Integration of orbitary polyethilene implants (MEDPOR). Histologic study].
abstract: OBJECTIVE
  We study the histological integration of high-density porous polyethylene orbital implants and its clinical meaning.
  
  
  METHODS
  During the last 16 months we have used 14 implants of MEDPOR. Two were removed because of migration, the first one and partial extrusion, the second one, after 3 and 9 months since implantation, respectively. They were preserved and softened in formaldehyde for one month, and later processed for histological study.
  
  
  RESULTS
  Macroscopically, a fibrous pseudocapsule firmly attached to the implant was seen. A fibrovascular tissue ingrowth covered the polyethylene porous surface and penetrated its total cross-sectional area. Occasional inflammatory cells were present. There was no evidence of macrophagical activity.
  
  
  CONCLUSIONS
  We demonstrate a good fibrovascular integration of the implant at the time of extraction. This means that this material can be successfully used in anophthalmic socket surgery. However, new pathological and clinical studies are necessary to elucidate their biocompatibility in long follow-up time.
authors.affiliation: Hospital Ramón y Cajal, Madrid, España.
authors.forename: A
authors.initials: A
authors.lastname: Núñez Sánchez
authors.forename: J A
authors.initials: JA
authors.lastname: Reche Sainz
authors.forename: A
authors.initials: A
authors.lastname: Sanz López
authors.forename: E
authors.initials: E
authors.lastname: Mateos Sánchez
authors.forename: G
authors.initials: G
authors.lastname: García Llanes
authors.forename: P
authors.initials: P
authors.lastname: San Miguel Fraile
authors.forename: C S
authors.initials: CS
authors.lastname: Fernández Escámez
mesh_terms: D000328:Adult; D001672:Biocompatible Materials; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000473:pathology; D020273:Orbital Implants; D011095:Polyethylenes
chemical_list: D001672:Biocompatible Materials; C084562:Medpor; D011095:Polyethylenes