Brain content of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid and immune response in aggressive C57bl/6J mice.
Catabolism of 5-hydroxytryptamine in the midbrain raphe nuclei of aggressive C57Bl/6J mice increased after 10 and 20 days of confrontations. Both catabolism and concentration of 5-hydroxytryptamine increased in the dopaminergic nuclei A11, A10, A9, and in the amygdala. The level of 5-hydroxyindoleacetic acid in the A9 and raphe nuclei decreased after 20 days of confrontations, which coincided with manifestation of the immune response.
Devoino
L B
LB
Laboratory of Neurochemical Modulation, Institute of Physiology, Siberian Division of Russian Academy of Medical Sciences.
Al'perina
E L
EL
Podgornaya
E K
EK
Polyakov
O V
OV
Idova
G V
GV
Il'yuchenok
R Y
RY
D000374:Aggression / Q000502:physiology*; D000818:Animals; D001921:Brain / Q000378:metabolism*; D006897:Hydroxyindoleacetic Acid / Q000032:analysis / Q000378:metabolism*; D007114:Immunization; D051379:Mice; D008810:Mice, Inbred C57BL / Q000276:immunology*; D012701:Serotonin / Q000032:analysis / Q000378:metabolism*; D012756:Sheep; D013154:Spleen / Q000276:immunology
D012701:Serotonin; D006897:Hydroxyindoleacetic Acid