title: Chemotherapy in the treatment of locally advanced cervical cancer and pregnancy.
abstract: BACKGROUND
  Carcinoma of the cervix is the most common malignant tumor associated with pregnancy. The initial stages and premalignant lesions apparently present the same prognosis in pregnant and nonpregnant women; however, there are limited data regarding outcome for locally advanced cervical cancer in pregnancy.
  
  
  METHODS
  A 26-year-old woman, gravida 4, para 3, at 14 weeks and 4 days' gestation, was diagnosed with a FIGO stage IIB squamous cell carcinoma of the cervix, treated by primary chemotherapy with cisplatin and bleomycin, until pregnancy resolution at 38 weeks. The newborn infant is currently 3 years old and presents no evidence of abnormalities in neuropsychomotor development.
  
  
  CONCLUSIONS
  The present case demonstrates that chemotherapy was harmless for the child up to the present time. However, a longer follow-up is needed to determine the safe outcome of this child.
authors.affiliation: Department of Gynecology and Obstetrics of the Medical School of Ribeirão Preto, University of São Paulo, SP 14.049-900, Brazil. heitorrcm@highnet.com.br
authors.forename: H R
authors.initials: HR
authors.lastname: Marana
authors.forename: J M
authors.initials: JM
authors.lastname: de Andrade
authors.forename: A C
authors.initials: AC
authors.lastname: da Silva Mathes
authors.forename: G
authors.initials: G
authors.lastname: Duarte
authors.forename: S P
authors.initials: SP
authors.lastname: da Cunha
authors.forename: S
authors.initials: S
authors.lastname: Bighetti
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy* / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000473:pathology