The dark side of a 'detoxification' mechanism.
Gillam
E M
EM
D000082:Acetaminophen / Q000009:adverse effects* / Q000493:pharmacokinetics; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects* / Q000493:pharmacokinetics; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005978:Glutathione / Q000378:metabolism; D051549:Glutathione S-Transferase pi; D005982:Glutathione Transferase / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D008658:Inactivation, Metabolic; D007527:Isoenzymes / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D018345:Mice, Knockout
D018712:Analgesics, Non-Narcotic; D007527:Isoenzymes; D000082:Acetaminophen; C496556:GSTP1 protein, human; D051549:Glutathione S-Transferase pi; D005982:Glutathione Transferase; C496557:Gstp1 protein, mouse; D005978:Glutathione