title: A fluoride-releasing composite for dental applications.
abstract: OBJECTIVE
  The aim of this work was to attempt formulation of a dental composite, for investigational purposes, which will release fluoride at a rate comparable to glass ionomer materials, while retaining physical properties adequate for potential use in a number of dental applications.
  
  
  METHODS
  An organic fluoride material, tetrabutylammonium tetrafluoroborate (TBATFB), was incorporated into a hydrophilic monomer system made of 2,2-bis[4-(2-hydroxy-3-methacroyloxypropoxy)phenyl]-propane (BisGMA) and 2-hydroxyethyl methacrylate (HEMA). This fluoride-containing monomer system was filled with silane treated quartz to 81 wt%. The resultant material was tested for fluoride release, physical strength properties and bond strength to enamel, each in comparison to control materials.
  
  
  RESULTS
  Cumulative fluoride release from the experimental composite was approximately linear over time and comparable to glass ionomer materials. The long term rate of release exceeded several of the glass ionomer materials tested. Diametral tensile strength was comparable to resin-modified glass ionomer (RMGI) materials. Bond strength to etched enamel was statistically equivalent to a commercially available hybrid composite control.
  
  
  CONCLUSIONS
  The experimental resin-based composite material could potentially be used as an alternative to glass ionomer materials in non-stress bearing restorative applications and for orthodontic bracket bonding, where high fluoride release is desirable.
authors.affiliation: 3M Health Care, 3M Center, Building 270-4N-01, St. Paul, MN 55144-1000, USA. eaglasspoole@mmm.com
authors.forename: E A
authors.initials: EA
authors.lastname: Glasspoole
authors.forename: R L
authors.initials: RL
authors.lastname: Erickson
authors.forename: C L
authors.initials: CL
authors.lastname: Davidson
mesh_terms: D000134:Acid Etching, Dental; D000818:Animals; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry; D001881:Borates / Q000737:chemistry; D002327:Cariostatic Agents / Q000737:chemistry*; D002417:Cattle; D003188:Composite Resins / Q000737:chemistry*; D019245:Compressive Strength; D001840:Dental Bonding; D003743:Dental Enamel / Q000648:ultrastructure; D003764:Dental Materials / Q000737:chemistry*; D017220:Dentin-Bonding Agents / Q000737:chemistry; D005459:Fluorides / Q000737:chemistry*; D005899:Glass Ionomer Cements / Q000737:chemistry; D006244:Hardness; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D011791:Quartz / Q000737:chemistry; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D019279:Resin Cements / Q000737:chemistry; D012821:Silanes / Q000737:chemistry; D012822:Silicon Dioxide; D012995:Solubility; D013223:Statistics as Topic; D013499:Surface Properties; D013718:Tensile Strength; D014867:Water / Q000737:chemistry; D015040:Zirconium
chemical_list: D001881:Borates; D002327:Cariostatic Agents; D003188:Composite Resins; D003764:Dental Materials; D017220:Dentin-Bonding Agents; D005899:Glass Ionomer Cements; D008689:Methacrylates; D000644:Quaternary Ammonium Compounds; D019279:Resin Cements; C084018:Scotchbond Multi-Purpose; D012821:Silanes; C083568:Z100 composite resin; D014867:Water; D011791:Quartz; C087244:tetrabutylammonium tetrafluoroborate; D017438:Bisphenol A-Glycidyl Methacrylate; C005044:hydroxyethyl methacrylate; D012822:Silicon Dioxide; D015040:Zirconium; D005459:Fluorides