title: Novel approach to bleeding in patients undergoing cardiac surgery with liver dysfunction.
abstract: We describe two patients with significant liver dysfunction (Child--Pugh class B) who underwent cardiac surgery at our institution facilitated by the use of a prothrombin complex concentrate for the management of postoperative bleeding.
authors.affiliation: Department of Cardiothoracic Surgery and Haematology, Southampton General Hospital, Southampton, UK. rstuklis@yahoo.com
authors.forename: R G
authors.initials: RG
authors.lastname: Stuklis
authors.forename: D F
authors.initials: DF
authors.lastname: O'Shaughnessy
authors.forename: S K
authors.initials: SK
authors.lastname: Ohri
mesh_terms: D000328:Adult; D001779:Blood Coagulation Factors / Q000627:therapeutic use*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D006331:Heart Diseases / Q000150:complications / Q000601:surgery; D006488:Hemostasis, Surgical; D006801:Humans; D008108:Liver Diseases, Alcoholic / Q000150:complications; D008297:Male; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000188:drug therapy*
chemical_list: D001779:Blood Coagulation Factors; C025667:prothrombin complex concentrates