title: Tumor progression: defining the soil round the tumor seed.
abstract: The tumor microenvironment, or stroma, is known to contribute to tumor progression. Two recent studies have shown that the stromal protein matrix metalloproteinase MMP-9 has a role in the early stages of tumor growth and angiogenesis.
authors.affiliation: Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232-2175, USA.
authors.forename: L J
authors.initials: LJ
authors.lastname: McCawley
authors.forename: L M
authors.initials: LM
authors.lastname: Matrisian
mesh_terms: D018450:Disease Progression; D020780:Matrix Metalloproteinase 9 / Q000502:physiology; D009369:Neoplasms / Q000098:blood supply / Q000473:pathology*; D009389:Neovascularization, Pathologic
chemical_list: D020780:Matrix Metalloproteinase 9