title: The tegument protein ppUL25 of human cytomegalovirus (CMV) is a major target antigen for the anti-CMV antibody response.
abstract: A viral protein of approximately 82 kDa is the only structural protein of human cytomegalovirus (CMV) that is strongly immunogenic during natural infection and the corresponding gene of which is still unknown. In this work, strong evidence is presented that this protein is the product of UL25.
authors.affiliation: Department of Clinical and Experimental Medicine, Division of Microbiology, Laboratory of Virology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy1.
authors.forename: Tiziana
authors.initials: T
authors.lastname: Lazzarotto
authors.affiliation: Department of Clinical and Experimental Medicine, Division of Microbiology, Laboratory of Virology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy1.
authors.forename: Stefania
authors.initials: S
authors.lastname: Varani
authors.affiliation: Department of Clinical and Experimental Medicine, Division of Microbiology, Laboratory of Virology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy1.
authors.forename: Liliana
authors.initials: L
authors.lastname: Gabrielli
authors.affiliation: Department of Clinical and Experimental Medicine, Division of Microbiology, Laboratory of Virology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy1.
authors.forename: Sara
authors.initials: S
authors.lastname: Pignatelli
authors.affiliation: Department of Clinical and Experimental Medicine, Division of Microbiology, Laboratory of Virology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy1.
authors.forename: Maria Paola
authors.initials: MP
authors.lastname: Landini
mesh_terms: D000327:Adsorption; D000914:Antibodies, Viral / Q000276:immunology; D000956:Antigens, Viral / Q000737:chemistry / Q000276:immunology*; D001782:Blood Donors; D003587:Cytomegalovirus / Q000737:chemistry / Q000276:immunology*; D005260:Female; D006801:Humans; D007106:Immune Sera / Q000276:immunology; D016056:Immunodominant Epitopes / Q000737:chemistry / Q000276:immunology*; D008297:Male; D008970:Molecular Weight; D016377:Organ Transplantation; D011247:Pregnancy; D014764:Viral Proteins / Q000737:chemistry / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D007106:Immune Sera; D016056:Immunodominant Epitopes; C087088:UL25 protein, Cytomegalovirus; D014764:Viral Proteins