title: Distal thoracic aorta as inflow for the treatment of chronic mesenteric ischemia.
abstract: OBJECTIVE
  Mesenteric revascularization for chronic mesenteric ischemia (CMI) traditionally involves antegrade or retrograde bypass graft originating from the supraceliac or infrarenal aorta. The distal thoracic aorta (DTA) may provide a better inflow source than the abdominal aorta. The purpose of this study was to evaluate the results with the DTA used as inflow for the surgical treatment of CMI.
  
  
  METHODS
  All patients undergoing mesenteric revascularization for CMI with grafts originating from the DTA were identified from 1990 to 1999. A ninth interspace thoracoretroperitoneal incision was used for exposure, and distal aortic flow was maintained by use of a partial occlusion clamp.
  
  
  RESULTS
  Eighteen consecutive patients with CMI underwent mesenteric bypass grafting with the DTA used as inflow. All patients were admitted with chronic abdominal pain or weight loss, with two (12%) requiring urgent revascularization because of acute exacerbation of chronic symptoms. Fourteen (78%) patients had both celiac and superior mesenteric artery bypass grafts placed, and three (17%) patients had superior mesenteric artery grafts alone. There was one (6%) perioperative death and three (17%) major complications. There was no kidney failure, mesenteric infarction, or spinal cord ischemia. The life-table survival rate was 89%, 89%, and 76% at 1, 3, and 5 years, respectively. All 18 patients remained symptom free and required no additional procedures to assist patency. There was no evidence of graft stenosis or occlusion (100% patency) for those grafts evaluated objectively during the mean follow-up of 34.8 months (range, 1-97 months).
  
  
  CONCLUSIONS
  Antegrade mesenteric revascularization with the DTA used as inflow is associated with low morbidity and mortality rates. Furthermore, it provides excellent midterm patency and survival results and should be considered as a primary approach for reconstruction of patients with CMI.
authors.affiliation: Division of Vascular Surgery, University of North Carolina, Chapel Hill, NC 27599-7212, USA. Mark_Farber@med.unc.edu
authors.forename: M A
authors.initials: MA
authors.lastname: Farber
authors.forename: R E
authors.initials: RE
authors.lastname: Carlin
authors.forename: W A
authors.initials: WA
authors.lastname: Marston
authors.forename: L V
authors.initials: LV
authors.lastname: Owens
authors.forename: S J
authors.initials: SJ
authors.lastname: Burnham
authors.forename: B A
authors.initials: BA
authors.lastname: Keagy
mesh_terms: D000328:Adult; D000368:Aged; D001013:Aorta, Thoracic / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation; D002445:Celiac Artery / Q000637:transplantation; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007511:Ischemia / Q000601:surgery; D015993:Life Tables; D008297:Male; D017538:Mesenteric Artery, Superior / Q000637:transplantation; D008641:Mesenteric Vascular Occlusion / Q000401:mortality / Q000601:surgery*; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D015996:Survival Rate; D014656:Vascular Surgical Procedures / Q000379:methods