Malignant spiradenoma: report of two cases and literature review.
Spiradenoma is a benign skin adnexal neoplasm that usually appears as a solitary nodule in any area of the body. There have been only 33 reports on malignant transformation of a benign eccrine spiradenoma since the first description by Dabska in 1972. Most cases have originated on a long-standing cutaneous lesion. These tumors can behave in an aggressive fashion, and some have led to the patient's death. We report 2 new cases of this rare neoplasm affecting 2 men, 92 and 72 years of age, comment on the clinical and pathologic features of our cases, and review the literature concerning this lesion.
Fernández-Aceñero
M J
MJ
Deparment of Pathology, Hospital General de Móstoles, Madrid, Spain. mgg10167@teleline.es
Manzarbeitia
F
F
Mestre de Juan
M J
MJ
Requena
L
L
D006607:Adenoma, Sweat Gland / Q000175:diagnosis / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology*; D012720:Severity of Illness Index; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000175:diagnosis / Q000473:pathology*