Typing of herpes simplex virus from human periodontium.
Herpes simplex virus (HSV) is frequently detected in gingival crevicular fluid and in gingival biopsies of periodontal lesions; however, the relative occurrence of HSV type 1 and 2 in periodontal specimens has not been established. This investigation used type-specific polymerase chain reaction (PCR) to detect the presence of HSV-1 and HSV-2 in periodontal pocket samples from 26 patients who had previously been revealed to have periodontal HSV by PCR amplification of a gene shared by HSV-1 and HSV-2. HSV-1 was detected in all 26 periodontal pocket specimens and HSV-2 was not detected. Apparently, HSV-2 is a rare inhabitant of periodontal sites.
Contreras
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Department of Periodontology, School of Dentistry, University of Southern California, Los Angeles 90089-0641, USA.
Slots
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D000328:Adult; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D005883:Gingival Crevicular Fluid / Q000821:virology; D005891:Gingivitis / Q000821:virology; D018259:Herpesvirus 1, Human / Q000145:classification*; D018258:Herpesvirus 2, Human / Q000145:classification*; D006801:Humans; D008297:Male; D017622:Periodontal Attachment Loss / Q000821:virology; D010514:Periodontal Pocket / Q000821:virology*; D010518:Periodontitis / Q000821:virology; D016133:Polymerase Chain Reaction
D004279:DNA, Viral