title: [New antidepressant drugs. What side effects and interactions are to be expected?].
abstract: The new antidepressants, selective serotonin reuptake inhibitors (SSRI), selective serotonin noradrenalin reuptake inhibitors (SSNRI) and selective noradrenalin reuptake inhibitors (SNRI) have few clinically relevant side effects. Overall, the new antidepressants are better tolerated and cause fewer side effects than the classical tricyclic antidepressants (TCA). They have virtually no anticholinergic effects, a low level of toxicity, and produce no psychomotoric or cognitive impairment. Both the frequency and severity of gastrointestinal and CNS side effects, as well as tremor, are low. The results of the drug safety program (AMSP) confirm the good tolerability and low clinical side effects of these new substances.
authors.affiliation: Psychiatrischen Klinik der Georg-August-Universität Göttingen.
authors.forename: D
authors.initials: D
authors.lastname: Degner
authors.forename: R
authors.initials: R
authors.lastname: Grohmann
authors.forename: S
authors.initials: S
authors.lastname: Bleich
authors.forename: E
authors.initials: E
authors.lastname: Rüther
mesh_terms: D000928:Antidepressive Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000145:classification; D003866:Depressive Disorder / Q000188:drug therapy*; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D006801:Humans
chemical_list: D000928:Antidepressive Agents