title: Stent deployment in calcified lesions: can we overcome calcific restraint with high-pressure balloon inflations?
abstract: Although significant coronary artery (CA) calcification is believed to affect stent deployment, the exact impact on stent deployment after high-pressure balloon inflations is unknown. Intracoronary intravascular examination (ICUS) was performed in 27 moderate-severe calcified CA lesions before and after stent implantation. In case of unsatisfactory results (in-stent area < 90%, minimal in-stent diameter/maximal in-stent diameter < 0.8), further inflations up to 20 atm guided by ICUS were applied. Initially, stent expansion was adequate in 10 stents (37%) and symmetric in 19 (70%). After inflation at 20 atm, stents with adequate expansion increased to 16 (59%, P = 0.0036), but stents with symmetry decreased to 13 (48%, P = 0.0045). Stent expansion was inversely correlated to the arc of calcium (r = -0.8, P < 0.0001). There were five patients with clinical restenosis at 6 months (18%). Increases in stent lumen area with high-pressure balloon inflations in moderate-severe calcified CA lesions are at the expense of symmetry. This may affect clinical restenosis.
authors.affiliation: Department of Cardiology, Hippokration Hospital, University of Athens, Greece. mvav@otenet.gr
authors.forename: M
authors.initials: M
authors.lastname: Vavuranakis
authors.forename: K
authors.initials: K
authors.lastname: Toutouzas
authors.forename: C
authors.initials: C
authors.lastname: Stefanadis
authors.forename: C
authors.initials: C
authors.lastname: Chrisohou
authors.forename: D
authors.initials: D
authors.lastname: Markou
authors.forename: P
authors.initials: P
authors.lastname: Toutouzas
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011312:Pressure; D011474:Prosthesis Design; D015607:Stents; D018084:Ultrasonography, Interventional