title: A conserved mechanism for post-transcriptional gene silencing?
abstract: Proteins with homology to RNA-directed RNA polymerases function in post-transcriptional gene silencing: in quelling in the fungus Neurospora crassa, RNAi in the nematode Caenorhabditis elegans, and co-suppression in the mustard plant Arabidopsis thaliana. These findings are consistent with a conserved mechanism operating in these diverse species.
authors.affiliation: Department of Biology, Syracuse University, Syracuse, NY 13244, USA. emmaine@syr.edu
authors.forename: E M
authors.initials: EM
authors.lastname: Maine
mesh_terms: D000818:Animals; D017360:Arabidopsis / Q000201:enzymology / Q000235:genetics; D029681:Arabidopsis Proteins; D017124:Conserved Sequence / Q000235:genetics; D019143:Evolution, Molecular; D020868:Gene Silencing; D017343:Genes, Plant / Q000235:genetics; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism; D012324:RNA-Dependent RNA Polymerase / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic / Q000235:genetics*
chemical_list: D029681:Arabidopsis Proteins; D010940:Plant Proteins; C410507:SGS3 protein, Arabidopsis; D012324:RNA-Dependent RNA Polymerase