title: Recruitment of American Indians and Alaska Natives into clinical trials.
abstract: Challenges in recruiting American Indians and Alaska Natives into cancer clinical trials are addressed in this article. Researchers, health care providers, and American Indian and Alaska Native patients face significant communication barriers when prevention or treatment trials are designed or implemented. For researchers, the challenges lie in understanding the cultural distinctiveness of individual tribes, coping with the family orientation of Indian subjects, dealing with the lack of standardized research measures, and defining the subject's pathway in seeking and obtaining healing and health care services. For providers, the challenges center on patient-provider communication, illness beliefs, transportation, and sociocultural barriers. This article explores these complex issues and offers recommendations for researchers and health care providers on conducting research in American Indian and Alaska Native populations.
authors.affiliation: Center for American Indian Research and Education, School of Nursing, University of California at San Francisco, Berkeley 94704, USA.
authors.forename: F S
authors.initials: FS
authors.lastname: Hodge
authors.forename: S
authors.initials: S
authors.lastname: Weinmann
authors.forename: Y
authors.initials: Y
authors.lastname: Roubideaux
mesh_terms: D000413:Alaska / Q000453:epidemiology; D001294:Attitude to Health; D002986:Clinical Trials as Topic; D003144:Communication Barriers; D003466:Cultural Characteristics; D003695:Delivery of Health Care / Q000458:organization & administration; D003710:Demography; D005006:Ethnicity / Q000706:statistics & numerical data*; D006305:Health Status Indicators; D006801:Humans; D007198:Indians, North American / Q000706:statistics & numerical data*; D009369:Neoplasms / Q000208:ethnology* / Q000628:therapy; D018579:Patient Selection; D012959:Socioeconomic Factors; D014481:United States / Q000453:epidemiology