[Membranous aspects of kidney transplantation and reasons of transplant antioxidant defense].
Special membranological studies of the role of antioxidant emoxipine in combined pharmacological support of stable function of the transplanted kidney in 30 patients have shown that this drug restores phospholipid pool of red cell membranes and improves their physical properties. No significant fluctuations of cyclosporin A blood concentrations were registered. Emoxipine addition to combined therapy of patients with transplanted kidney is recommended.
Berdichevskiĭ
B A
BA
Tsvettskikh
V E
VE
Zhmurov
V A
VA
Kononov
S L
SL
Berdichevskaia
E B
EB
Zhuravleva
T D
TD
Kiianiuk
N S
NS
Razumiak
T V
TV
Nedorezoniuk
S V
SV
D000975:Antioxidants / Q000378:metabolism* / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000378:metabolism; D006084:Graft Rejection / Q000378:metabolism / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007668:Kidney / Q000187:drug effects / Q000378:metabolism*; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000601:surgery; D016030:Kidney Transplantation / Q000502:physiology*; D015227:Lipid Peroxidation / Q000187:drug effects / Q000502:physiology; D008566:Membranes / Q000187:drug effects / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D010847:Picolines / Q000627:therapeutic use
D000975:Antioxidants; D007166:Immunosuppressive Agents; D010743:Phospholipids; D010847:Picolines; D016572:Cyclosporine; C009820:6-methyl-2-ethyl-3-hydroxypyridine