Protein arrays and microarrays.
In the past, studies of protein activities have focused on studying a single protein at a time, which is often time-consuming and expensive. Recently, with the sequencing of entire genomes, large-scale proteome analysis has begun. Arrays of proteins have been used for the determination of subcellular localization, analysis of protein-protein interactions and biochemical analysis of protein function. New protein-microarray technologies have been introduced that enable the high-throughput analysis of protein activities. These have the potential to revolutionize the analysis of entire proteomes.
Zhu
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Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut 06520, USA.
Snyder
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M
D000818:Animals; D001709:Biotechnology / Q000379:methods / Q000639:trends; D005544:Forecasting; D006801:Humans; D011506:Proteins / Q000032:analysis* / Q000378:metabolism; D020543:Proteome / Q000032:analysis; D012371:Robotics / Q000379:methods / Q000639:trends
D011506:Proteins; D020543:Proteome