Hydrogen bonding in two tetracyclic indole alkaloids.
3-Acetyl-1,6,7,12b-tetrahydroindolo[2,3-a]quinolizin-2(12H)-one, C17H16N2O2, consists of two symmetry-independent molecules and each forms a layered structure stabilized by N-H...O and C-H...O hydrogen bonds. In 3-acetyl-6,7-dihydroindolo[2,3-a]quinolizin-4(12H)-one monohydrate, C17H14)N2O2.H2O, the structure is stabilized by O-H...O, N-H...O and C-H...O hydrogen bonds, with the ordered water molecule playing a crucial role in the self-assembly. Contribution from the weak interactions to the strong hydrogen-bonded network is a common feature in both structures.
Varma
A K
AK
School of Chemistry, University of Hyderabad, Hyderabad 500 046, India.
Nangia
A
A
Desiraju
G R
GR
Giri
V S
VS
Jaisankar
P
P
D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D007211:Indoles / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D011799:Quinazolines / Q000737:chemistry*; D011807:Quinolizines / Q000737:chemistry*
C425410:3-Acetyl-1,6,7,12b-tetrahydroindolo(2,3-a)quinolizin-2(12H)-one monohydrate; C425409:3-acetyl-6,7-dihydroindolo(2,3-a)quinolizin-4(12H)-one monohydrate; D007211:Indoles; D011799:Quinazolines; D011807:Quinolizines