Combining nucleic acid amplification and detection.
Major recent advances in molecular amplification in the past year were initial validation of two new amplification technologies (rolling circle amplification and Invader), a significant increase in the number of molecular diagnostic assays, achievement of amplification directly on microarrays (by strand displacement amplification and rolling circle amplification), and description of two new read-out probes (Scorpions and nanoparticles).
Schweitzer
B
B
Molecular Staging Inc., 66 High Street, Guilford, CT 06437, USA. barrys@molecularstaging.com
Kingsmore
S
S
D004270:DNA, Circular; D022521:Ligase Chain Reaction; D008967:Molecular Biology / Q000379:methods; D021141:Nucleic Acid Amplification Techniques; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D016133:Polymerase Chain Reaction; D011933:Reagent Kits, Diagnostic
D004270:DNA, Circular; D011933:Reagent Kits, Diagnostic