title: Plasmapheresis as an effective treatment for opsoclonus-myoclonus syndrome.
abstract: A 6-year-old female diagnosed with idiopathic opsoclonus-myoclonus syndrome at 22 months of age who failed to respond to treatment with adrenocorticotropic hormone (ACTH), IV gammaglobulin (IVIG), and azathioprine is presented. Because of marked and progressive deterioration in motor function and speech, this patient received a course of plasmapheresis with concomitant steroids and azathioprine. Within 1 week, marked improvements in motor function were noted. Eighteen months later, the patient ambulates, walks without support, and attends a regular school in the appropriate grade level.
authors.affiliation: Division of Pediatric Nephrology, University of Alberta, Edmonton, Canada.
authors.forename: V W
authors.initials: VW
authors.lastname: Yiu
authors.forename: T
authors.initials: T
authors.lastname: Kovithavongs
authors.forename: L F
authors.initials: LF
authors.lastname: McGonigle
authors.forename: P
authors.initials: P
authors.lastname: Ferreira
mesh_terms: D001379:Azathioprine / Q000008:administration & dosage; D002648:Child; D003131:Combined Modality Therapy; D018450:Disease Progression; D005260:Female; D006801:Humans; D009460:Neurologic Examination / Q000187:drug effects; D020361:Paraneoplastic Syndromes, Nervous System / Q000175:diagnosis / Q000628:therapy*; D010956:Plasmapheresis; D011241:Prednisone / Q000008:administration & dosage
chemical_list: D001379:Azathioprine; D011241:Prednisone