title: The prenatal diagnosis of Binder syndrome before 24 weeks of gestation: case report.
abstract: A case of Binder syndrome was diagnosed at 21 weeks of gestation using two-dimensional and three-dimensional ultrasound. The first indication of any abnormality was a flattened fetal nose demonstrated in the mid-sagittal plane. Further ultrasound imaging showed the virtual absence of the naso-frontal angle, giving the impression of a flat forehead and small fetal nose. Suspected mild hypertelorism was also seen using transverse and coronal planes. Differential diagnosis of this condition is discussed.
authors.affiliation: Department of Obstetrics and Gynaecology, St, George's Hospital Medical School, London, UK.
authors.forename: K
authors.initials: K
authors.lastname: Cook
authors.forename: F
authors.initials: F
authors.lastname: Prefumo
authors.forename: F
authors.initials: F
authors.lastname: Presti
authors.forename: T
authors.initials: T
authors.lastname: Homfray
authors.forename: S
authors.initials: S
authors.lastname: Campbell
mesh_terms: D000328:Adult; D003394:Craniofacial Dysostosis / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008437:Maxilla / Q000002:abnormalities*; D009295:Nasal Bone / Q000002:abnormalities*; D011247:Pregnancy; D013577:Syndrome; D016216:Ultrasonography, Prenatal