title: A calcifying fibroma of the meninges report of a case and review of the literature.
abstract: We report an unusual tumor related to the meninges designated as a calcifying fibroma of the meninges. Our patient was a 44-year-old man.The tumor was located in the right frontotemporoparietal region and was excised totally via a right frontotemporoparietal craniotomy. The patient had recovered completely, and no recurrence was observed in a follow-up period of three years. Histopathologically, we noted scattered spindle cells among the hyalinized collagenous stroma, dystrophicpsammomatous calcifications, abundant perivascular hyalinization and cartilagenous metaplasia. Immunohistochemically, the tumor cells showed actin, smooth muscle and vimentin immunreactivities. Ultrastructurally, spindle cells showed fibroblastic features. The lesion is a true tumor and it should be kept in mind in the differential diagnoss of meningeal calcifying lesions.
authors.affiliation: Department of Pathology, Gülhane Military Medical Academy, Ankara, Turkey. ceyhank@hotmail.com
authors.forename: K
authors.initials: K
authors.lastname: Ceyhan
authors.forename: Q
authors.initials: Q
authors.lastname: Berk
authors.forename: S
authors.initials: S
authors.lastname: Caglar
authors.forename: S
authors.initials: S
authors.lastname: Sürücü
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002114:Calcinosis / Q000473:pathology* / Q000601:surgery; D005350:Fibroma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007124:Immunoenzyme Techniques; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D009363:Neoplasm Proteins / Q000032:analysis
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins