[Animal motor activity and cerebellar beta-adrenoreceptors after disturbance of the glucocorticoid balance].
The number of divings of rats in the forced-swimming test increased after adrenalectomy and/or dexamethasone treatment. The activation of the behavior was accompanied by an increase in the density of beta-adrenoreceptors in the cerebellum of these animals. These adrenoreceptors can be a necessary link in the pathway of signal transmission that underlies the behavioral effects of glucocorticoids acting intracellularly.
Surnina
H Iu
HIu
Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Branch, Novosibirsk.
Dygalo
N N
NN
D000315:Adrenalectomy; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D002531:Cerebellum / Q000378:metabolism*; D003907:Dexamethasone / Q000494:pharmacology; D005938:Glucocorticoids / Q000502:physiology*; D008297:Male; D009043:Motor Activity; D051381:Rats; D017208:Rats, Wistar; D011943:Receptors, Adrenergic, beta / Q000378:metabolism*
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D011943:Receptors, Adrenergic, beta; D003907:Dexamethasone