title: Recurrent endogenous candidal endophthalmitis in a premature infant.
abstract: Endogenous Candida endophthalmitis resulting from candidemia in low-birth-weight infants usually occurs as a retinochoroiditis, which is effectively treated with systemic antifungal agents. We report a case of Candida endophthalmitis that recurred 4 months after completion of systemic antifungal therapy. The recurrent Candida infection affected primarily the iris and lens, rather than the retina and choroid. Vitrectomy was required for diagnosis and treatment.
authors.affiliation: Department of Ophthalmology, Lions Eye Institute, Albany Medical College, New York 12208, USA.
authors.forename: J H
authors.initials: JH
authors.lastname: Stern
authors.forename: C
authors.initials: C
authors.lastname: Calvano
authors.forename: J W
authors.initials: JW
authors.lastname: Simon
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D015784:Betaxolol / Q000627:therapeutic use; D002176:Candida albicans / Q000302:isolation & purification*; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D009877:Endophthalmitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007908:Lens, Crystalline / Q000382:microbiology / Q000601:surgery; D008826:Microbial Sensitivity Tests; D011239:Prednisolone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D012008:Recurrence; D014821:Vitrectomy; D014822:Vitreous Body / Q000382:microbiology
chemical_list: D000666:Amphotericin B; C009935:prednisolone acetate; D011239:Prednisolone; D015784:Betaxolol; D005472:Fluorouracil