title: Solitary fibrous tumor of the prostate a report of 2 cases and review of the literature.
abstract: We report 2 cases of solitary fibrous tumor of the prostate. Histologically, both tumors demonstrated a multipatterned architecture with varying degrees of collagenization and hemangiopericytoma-like foci, and both were composed of CD34-immunopositive spindled cells that insinuated themselves between strips of collagen. The tumor in case 1 was well circumscribed and showed minimal mitotic activity or pleomorphism, whereas the tumor in case 2 was more cellular, less collagenous, had a more diffuse growth pattern, and exhibited cytologic atypia and high mitotic activity. Prostatic solitary fibrous tumor must be distinguished from other spindle cell tumors reported to occur in the prostate. To our knowledge, these cases represent only the fifth and sixth reported cases of prostatic solitary fibrous tumor.
authors.affiliation: Department of Pathology, Northwestern University Medical School, Chicago, IL USA.
authors.forename: M R
authors.initials: MR
authors.lastname: Pins
authors.forename: S C
authors.initials: SC
authors.lastname: Campbell
authors.forename: W B
authors.initials: WB
authors.lastname: Laskin
authors.forename: K
authors.initials: K
authors.lastname: Steinbronn
authors.forename: D P
authors.initials: DP
authors.lastname: Dalton
mesh_terms: D000368:Aged; D018952:Antigens, CD34 / Q000032:analysis; D002277:Carcinoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D002455:Cell Division; D003094:Collagen / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D008938:Mitosis; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D018952:Antigens, CD34; D003094:Collagen