Computational methods for protein function analysis.
Two recent advances have had the greatest impact on protein function analysis so far: the complete sequences of genomes and mRNA expression level profiles. The former has spurred the development of novel techniques to study protein function: phylogenetic profiles and gene clusters. The latter has introduced a method, not based on sequence homology, that enables one to group together functionally related genes.
Pellegrini
M
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Protein Pathways, 1145 Gayley Avenue, Suite 304, Los Angeles, CA 90024, USA. matteope@proteinpathways.com
D000818:Animals; D001709:Biotechnology / Q000379:methods*; D019295:Computational Biology / Q000379:methods*; D020869:Gene Expression Profiling / Q000379:methods; D006801:Humans; D005810:Multigene Family; D010802:Phylogeny; D011506:Proteins / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D016415:Sequence Alignment
D011506:Proteins