title: Computational methods for protein function analysis.
abstract: Two recent advances have had the greatest impact on protein function analysis so far: the complete sequences of genomes and mRNA expression level profiles. The former has spurred the development of novel techniques to study protein function: phylogenetic profiles and gene clusters. The latter has introduced a method, not based on sequence homology, that enables one to group together functionally related genes.
authors.affiliation: Protein Pathways, 1145 Gayley Avenue, Suite 304, Los Angeles, CA 90024, USA. matteope@proteinpathways.com
authors.forename: M
authors.initials: M
authors.lastname: Pellegrini
mesh_terms: D000818:Animals; D001709:Biotechnology / Q000379:methods*; D019295:Computational Biology / Q000379:methods*; D020869:Gene Expression Profiling / Q000379:methods; D006801:Humans; D005810:Multigene Family; D010802:Phylogeny; D011506:Proteins / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D016415:Sequence Alignment
chemical_list: D011506:Proteins