title: Dynamics of behavioral risk factors for HIV/AIDS: a 6-year prospective study of injection drug users.
abstract: This prospective study of 2960 injection drug users investigated the dynamic nature of HIV behavioral risk factors between 1988 and 1994. Behavioral risks were assessed semi-annually. Robust regression models of time-dependent covariates were used to identify longitudinal predictors of behavior change. Maintenance of risky behaviors varied over time, with risk reduction seen more among HIV infected participants than among HIV seronegatives. Those at highest risk for HIV transmission were least likely to cease engaging in these behaviors. Interventions staged according to risk behaviors, targeting incremental risk reduction rather than only promoting abstinence, may be more successful in reducing HIV transmission among drug injectors.
authors.affiliation: Department of Epidemiology, The Johns Hopkins School of Hygiene and Public Health, 615 N. Wolfe St. (Room E6008), Baltimore, MD 21205, USA. dcelenta@jhsph.edu
authors.forename: D D
authors.initials: DD
authors.lastname: Celentano
authors.forename: A
authors.initials: A
authors.lastname: Muñoz
authors.forename: S
authors.initials: S
authors.lastname: Cohn
authors.forename: D
authors.initials: D
authors.lastname: Vlahov
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000523:psychology*; D000328:Adult; D005260:Female; D006678:HIV; D015438:Health Behavior; D006801:Humans; D016015:Logistic Models; D008297:Male; D015999:Multivariate Analysis; D016017:Odds Ratio; D011446:Prospective Studies; D012309:Risk-Taking; D015819:Substance Abuse, Intravenous / Q000523:psychology*