Treatment of recurrent or progressive malignant glioma with a recombinant adenovirus expressing human interferon-beta (H5.010CMVhIFN-beta): a phase I trial.
Eck
S L
SL
University of Pennsylvania Cancer Center, Philadelphia 19104, USA.
Alavi
J B
JB
Judy
K
K
Phillips
P
P
Alavi
A
A
Hackney
D
D
Cross
P
P
Hughes
J
J
Gao
G
G
Wilson
J M
JM
Propert
K
K
D000256:Adenoviridae / Q000235:genetics* / Q000378:metabolism; D000293:Adolescent; D000328:Adult; D000818:Animals; D001932:Brain Neoplasms / Q000378:metabolism / Q000401:mortality / Q000628:therapy* / Q000821:virology; D015870:Gene Expression; D015316:Genetic Therapy; D005910:Glioma / Q000378:metabolism / Q000401:mortality / Q000628:therapy* / Q000821:virology; D006801:Humans; D016899:Interferon-beta / Q000096:biosynthesis*; D008253:Macaca mulatta / Q000235:genetics / Q000821:virology; D008279:Magnetic Resonance Imaging; D051379:Mice; D008810:Mice, Inbred C57BL; D012008:Recurrence; D018570:Risk Assessment; D012449:Safety; D015996:Survival Rate; D016896:Treatment Outcome
D016899:Interferon-beta