Haploinsufficiency for tumor suppression: the hazards of being single and living a long time.
Largaespada
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Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA. larga002@tc.umn.edu
D017209:Apoptosis / Q000235:genetics; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D018628:Gene Dosage; D016147:Genes, Tumor Suppressor; D015473:Leukemia, Promyelocytic, Acute / Q000209:etiology* / Q000235:genetics; D009363:Neoplasm Proteins / Q000378:metabolism*; D015514:Oncogene Proteins, Fusion / Q000378:metabolism*; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000235:genetics / Q000378:metabolism*; D019076:Transgenes
D009363:Neoplasm Proteins; D015514:Oncogene Proteins, Fusion; D019253:Proto-Oncogene Proteins c-bcl-2; C093476:promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein