Microtubules don and doff their caps: dynamic attachments at plus and minus ends.
Microtubule plus end dynamics, as well as interactions with the cell cortex and internal organelles, may be mediated by a 'plus end complex' of interacting proteins. Recent results suggest that centrosomes with different microtubule-releasing and anchoring properties underlie the development of various microtubule arrays.
Schroer
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Department of Biology, The Johns Hopkins University, 3400 N Charles Street, Baltimore, Maryland 21218, USA. scroer@jhu.edu
D000818:Animals; D006801:Humans; D008868:Microtubule Proteins / Q000737:chemistry* / Q000502:physiology*; D008869:Microtubule-Associated Proteins / Q000737:chemistry / Q000502:physiology; D020409:Molecular Motor Proteins / Q000737:chemistry* / Q000502:physiology*
D008868:Microtubule Proteins; D008869:Microtubule-Associated Proteins; D020409:Molecular Motor Proteins