title: Soft tissue response to clinically contaminated and thereafter cleaned titanium surfaces. An experimental study in the rat.
abstract: The aim of the present study was to evaluate the soft tissue response to intra-orally exposed and contaminated titanium surfaces (machined, blasted or polished) after being chemically and/or mechanically cleaned. Eight adult Sprague-Dawley rats were used for histomorphometrical and histological analyses. A total of 44 experimental abutments (26 tests and 18 controls) were inserted into abdominal skinpockets of the rats for 6 weeks. No differences regarding the soft tissue response between the different surface characteristics analysed and between test and control could be observed.
authors.affiliation: Department of Prosthetic Dentistry, Faculty of Odontology, Malmö University, Malmö, Sweden.
authors.forename: I
authors.initials: I
authors.lastname: Ericsson
authors.forename: U
authors.initials: U
authors.lastname: Lekholm
authors.forename: L
authors.initials: L
authors.lastname: Sennerby
authors.forename: A
authors.initials: A
authors.lastname: Holmén
mesh_terms: D000005:Abdomen; D000368:Aged; D000818:Animals; D000044:Dental Abutments / Q000382:microbiology*; D015921:Dental Implants / Q000382:microbiology*; D003775:Dental Polishing; D062109:Dermatologic Surgical Procedures; D003902:Detergents / Q000627:therapeutic use; D004202:Disinfectants / Q000627:therapeutic use; D004563:Electrochemistry; D004983:Ethanolamines / Q000627:therapeutic use; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D008264:Macrophages / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009025:Morpholines / Q000627:therapeutic use; D009055:Mouth / Q000382:microbiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000473:pathology*; D012965:Sodium Chloride; D013242:Sterilization / Q000379:methods; D013499:Surface Properties; D013501:Surface-Active Agents / Q000627:therapeutic use; D014025:Titanium
chemical_list: D015921:Dental Implants; D003902:Detergents; D004202:Disinfectants; D004983:Ethanolamines; D009025:Morpholines; D013501:Surface-Active Agents; C009495:titanium dioxide; D012965:Sodium Chloride; D014025:Titanium; C073738:delmopinol