Polyunsaturated fatty acid-specific elongation enzymes.
We have isolated a novel gene (GLELO) from Mortierella alpina and its homologue (CEELO1) from Caenorhabditis elegans and demonstrate the involvement of their encoded proteins in the elongation of C(18) polyunsaturated fatty acids.
Das
T
T
Ross Products Division, Abbott Laboratories, Columbus, OH 43215, USA.
Thurmond
J M
JM
Bobik
E
E
Leonard
A E
AE
Parker-Barnes
J M
JM
Huang
Y S
YS
Mukerji
P
P
D000123:Acetyltransferases / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D017173:Caenorhabditis elegans / Q000201:enzymology; D003001:Cloning, Molecular; D000081031:Fatty Acid Elongases; D005231:Fatty Acids, Unsaturated / Q000378:metabolism*; D007700:Kinetics; D009090:Mucorales / Q000201:enzymology* / Q000235:genetics; D011994:Recombinant Proteins / Q000378:metabolism; D012441:Saccharomyces cerevisiae; D013379:Substrate Specificity
D005231:Fatty Acids, Unsaturated; D011994:Recombinant Proteins; D000123:Acetyltransferases; D000081031:Fatty Acid Elongases