Ultrasound, antisperm antibody, and hormone profiles after testicular Trucut biopsy.
OBJECTIVE
To assess the effect of Trucut needle biopsy on the ultrasound appearances of the testis in obstructive and nonobstructive azoospermia to test serum samples for antisperm antibodies and gonadotropin and testosterone levels.


METHODS
Prospective case analysis.


METHODS
IVF unit.


METHODS
Sixteen subjects with obstructive azoospermia had postbiopsy ultrasound scans, 18 had assessment of hormone profiles, and 20 had evaluation of antisperm antibodies.


METHODS
Trucut needle testicular biopsies under local anesthetic.


METHODS
Postbiopsy testicular ultrasound, the presence of serum antisperm antibodies, and follicle stimulating and luteinizing hormone and testosterone levels.


RESULTS
There were no postbiopsy hematomas or scars, antisperm antibodies did not develop, and pituitary gonadotropins did not rise nor testosterone levels fall.


CONCLUSIONS
Trucut needle testicular biopsy in men with obstructive azoospermia is not associated with defects of parenchymal structure or function.
Steele
E K
EK
School of Medicine, Department of Obstetrics and Gynecology, The Queen's University of Belfast, Grosvenor Road, Belfast BT12 6BJ, Northern Ireland, United Kingdom.
Ellis
P K
PK
Lewis
S E
SE
McClure
N
N
D001323:Autoantibodies / Q000097:blood*; D001707:Biopsy, Needle / Q000379:methods*; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009845:Oligospermia / Q000276:immunology / Q000473:pathology*; D013094:Spermatozoa / Q000276:immunology*; D013737:Testis / Q000000981:diagnostic imaging* / Q000473:pathology*; D013739:Testosterone / Q000097:blood; D014463:Ultrasonography
D001323:Autoantibodies; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone