title: The validity of health claims on the World Wide Web: a systematic survey of the herbal remedy Opuntia.
abstract: OBJECTIVE
  The World Wide Web has become a significant source of health information for the public, but there is concern that much of the information is inaccurate, misleading, and unsupported by scientific evidence. To explore this issue, the validity of health claims for the herb Opuntia on the World Wide Web was analyzed.
  
  
  METHODS
  From December 1998 to May 1999, health claims were identified from Web sites utilizing nine search engines. A corresponding search was conducted of the scientific literature. Search terms included common and botanical names for Opuntia.
  
  
  METHODS
  Nutritional support guidelines for herbs were used to identify claims from relevant sites. Scientific studies included established methodological designs with no restrictions on source, language, type of subjects, or dosage forms for Opuntia.
  
  
  METHODS
  A checklist of significant information was prepared for Web sites and scientific studies. The quality of scientific studies was assessed with two instruments, the Jadad and the Journal of the American Medical Association (JAMA) scales.
  
  
  RESULTS
  Validity of health claims on Web sites was compared with scientific reports. Searches retrieved 184 Web sites, 98 with health claims and 51 with research studies. Only 34% of the claims were addressed in the scientific literature, and evidence was conflicting or contradictory. For human studies, none met the criteria for high quality as determined by the Jadad and JAMA scales.
  
  
  CONCLUSIONS
  The majority of health claims were based on folklore or indirect scientific evidence and could not be validated by scientific research. This suggests a need to check the validity of herbal information on the World Wide Web.
authors.affiliation: Veteran's Affairs Medical Center, Phoenix, Arizona, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Veronin
authors.forename: G
authors.initials: G
authors.lastname: Ramirez
mesh_terms: D004346:Drug Information Services / Q000592:standards*; D006801:Humans; D020407:Internet; D029747:Opuntia; D008517:Phytotherapy; D028321:Plant Preparations / Q000627:therapeutic use*
chemical_list: D028321:Plant Preparations