title: Fluoride concentrations at and near the neonatal line in human deciduous tooth enamel obtained from a naturally fluoridated and a non-fluoridated area.
abstract: This study sought to obtain a precise profile of fluoride concentrations at and near the neonatal line in deciduous incisors and canines from the naturally fluoridated area (1.0--1.3 parts/10(6) F in drinking water) of West Hartlepool and the non-fluoridated area (less than 0.1 parts/10(6) F in drinking water) of Leeds in England. An abrasive microsampling method was used to determine the distribution of fluoride and phosphorus concentrations. The profile of fluoride concentrations in 100-microm layers before and after the neonatal line, that is, in the prenatal and postnatal enamel, were significantly higher in teeth from the fluoridated than non-fluoridated areas. It was concluded that the fact that the fluoride concentrations were about the same prenatally and postnatally in deciduous enamel obtained from the fluoridated and non-fluoridated areas indicates that fluoride enters the prenatal deciduous enamel and that it is transferred through the placenta.
authors.affiliation: Department of Preventive Dentistry and Dental Public Health, School of Dentistry, Aichi-Gakuin University, 1-100 Kusumoto-cho, Chikusa-ku, Nagoya 464-8650, Japan. nakagaki@dpc.aichi-gakuin.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Toyama
authors.forename: H
authors.initials: H
authors.lastname: Nakagaki
authors.forename: S
authors.initials: S
authors.lastname: Kato
authors.forename: S
authors.initials: S
authors.lastname: Huang
authors.forename: Y
authors.initials: Y
authors.lastname: Mizutani
authors.forename: S
authors.initials: S
authors.lastname: Kojima
authors.forename: A
authors.initials: A
authors.lastname: Toyama
authors.forename: N
authors.initials: N
authors.lastname: Ohno
authors.forename: T
authors.initials: T
authors.lastname: Tsuchiya
authors.forename: J
authors.initials: J
authors.lastname: Kirkham
authors.forename: C
authors.initials: C
authors.lastname: Robinson
mesh_terms: D002118:Calcium / Q000032:analysis; D002675:Child, Preschool; D003743:Dental Enamel / Q000737:chemistry*; D004577:Electron Probe Microanalysis; D004739:England; D005260:Female; D005457:Fluoridation; D005459:Fluorides / Q000032:analysis*; D006801:Humans; D008431:Maternal-Fetal Exchange; D010710:Phosphates / Q000032:analysis; D011247:Pregnancy
chemical_list: D010710:Phosphates; D005459:Fluorides; D002118:Calcium