The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis. EASI Evaluator Group.
OBJECTIVE
To test the reliability of the eczema area and severity index (EASI) scoring system by assessing inter- and intra-observer consistency.


METHODS
Training of evaluators, application, and assessment over 2 consecutive days.


METHODS
An academic center.


METHODS
Twenty adults and children with atopic dermatitis (AD); cohort 1 (10 patients > or = 8 years) and cohort 2 (10 patients < 8 years).


METHODS
None.


METHODS
The EASI was used by 15 dermatologist evaluators to assess atopic dermatitis in cohort 1 and cohort 2 on 2 consecutive days. Inter- and intraobserver reliability were analyzed.


RESULTS
Overall intra-evaluator reliability of the EASI was in the fair-to-good range. Inter-evaluator reliability analyses indicated that the evaluators assessed the patients consistently across both study days.


CONCLUSIONS
This study demonstrated that the EASI can be learned quickly and utilized reliably in the assessment of severity and extent of AD. There was consistency among the evaluators between consecutive days of evaluation. These results support the use of the EASI in clinical trials of therapeutic agents for AD.
Hanifin
J M
JM
Department of Dermatology, Oregon Health Sciences University, Portland 97201-3098, USA. hanifinj@ohsu.edu
Thurston
M
M
Omoto
M
M
Cherill
R
R
Tofte
S J
SJ
Graeber
M
M
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003876:Dermatitis, Atopic / Q000145:classification / Q000175:diagnosis*; D003880:Dermatology / Q000295:instrumentation*; D004485:Eczema / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015588:Observer Variation; D015203:Reproducibility of Results; D012720:Severity of Illness Index