title: Characterization and chromosomal localization of the chicken avidin gene family.
abstract: Chicken avidin is a biotin-binding protein expressed under inflammation in several chicken tissues and in the oviduct after progesterone induction. The gene encoding avidin belongs to a family that has been shown to include multiple genes homologous to each other. The screening and chromosomal localization studies performed to reveal the structure and organization of the complete avidin gene family is described. The avidin gene family is arranged in a single cluster within a 27-kb genomic region. The cluster is located on the sex chromosome Z on band q21. The organization of the genes was determined and two novel avidin-related genes, AVR6 and AVR7, were cloned and sequenced.
authors.affiliation: University of Jyväskylä, Department of Biological and Environmental Science, Finland.
authors.forename: M K
authors.initials: MK
authors.lastname: Ahlroth
authors.forename: E H
authors.initials: EH
authors.lastname: Kola
authors.forename: D
authors.initials: D
authors.lastname: Ewald
authors.forename: J
authors.initials: J
authors.lastname: Masabanda
authors.forename: A
authors.initials: A
authors.lastname: Sazanov
authors.forename: R
authors.initials: R
authors.lastname: Fries
authors.forename: M S
authors.initials: MS
authors.lastname: Kulomaa
mesh_terms: D000818:Animals; D001360:Avidin / Q000235:genetics*; D001483:Base Sequence; D002645:Chickens / Q000235:genetics*; D002874:Chromosome Mapping / Q000662:veterinary*; D003001:Cloning, Molecular; D003360:Cosmids; D004247:DNA; D017404:In Situ Hybridization, Fluorescence; D008969:Molecular Sequence Data; D012689:Sequence Homology, Nucleic Acid
chemical_list: D001360:Avidin; D004247:DNA