title: Laparoscopy and tribology: the effect of laparoscopic gas on peritoneal fluid.
abstract: OBJECTIVE
  To assess the changes in viscosity of peritoneal fluid during laparoscopic exposure to CO2 insufflation.
  
  
  METHODS
  Analysis and mathematic modeling of peritoneal fluid viscosity in vivo and in vitro as a result of exposure to unconditioned CO2 (Canadian Task Force classification II-2).
  
  
  METHODS
  Medical school university research laboratory and hospital.
  
  
  METHODS
  Peritoneal fluid from 45 women.
  
  
  METHODS
  Peritoneal fluid was obtained at laparoscopy before insufflation and tested for viscosity after exposure to currently used raw dry unconditioned CO2.
  
  
  RESULTS
  Peritoneal fluid viscosity was tested by viscometric methods and mathematic modeling. Initial viscosity of peritoneal fluid before gas exposure was 1.425 centipoise (cP). Viscosity measurements were obtained at 20-second intervals for gas flows of 1 and 3 L/minute. Increases in viscosity occur rapidly, and by 200 seconds it was 59 cP and 98 cP for 1 and 3 L flow rates, respectively.
  
  
  CONCLUSIONS
  Very dry CO2 for laparoscopy causes peritoneal fluid viscosity to increase dramatically. (J Am Assoc Gynecol Laparosc 8(1):117-123, 2001)
authors.affiliation: Department of Biomedical and Environmental Engineering, Mercer University School of Engineering, Macon, GA 31207.
authors.forename: D E
authors.initials: DE
authors.lastname: Ott
mesh_terms: D000328:Adult; D001202:Ascitic Fluid; D002245:Carbon Dioxide; D003681:Dehydration; D005260:Female; D006801:Humans; D010535:Laparoscopy; D011028:Pneumoperitoneum, Artificial; D014783:Viscosity
chemical_list: D002245:Carbon Dioxide