title: The tubulin fraternity: alpha to eta.
abstract: Microtubules perform essential and diverse functions in eukaryotic cells. They are required for spindles during mitosis and meiosis, for axonal transport, for organelle positioning, and for cilia and flagella. gamma-tubulin is necessary to initiate the assembly of alpha-beta tubulin heterodimers into microtubule polymers. Recent genetic analyses and database searches have added four new members of the tubulin superfamily, which now includes alpha-, beta-, gamma-, delta-, epsilon-, zeta-, and eta-tubulin.
authors.affiliation: Department of Genetics, School of Medicine, Washington University, Campus Box 8232, 4566 Scott Avenue, St Louis, Missouri 63110, USA. dutcher@genetics.wustl.edu
authors.forename: S K
authors.initials: SK
authors.lastname: Dutcher
mesh_terms: D000818:Animals; D019143:Evolution, Molecular; D006801:Humans; D005810:Multigene Family; D020033:Protein Isoforms / Q000737:chemistry; D014404:Tubulin / Q000737:chemistry*
chemical_list: D020033:Protein Isoforms; D014404:Tubulin