title: Malignant spiradenoma: report of two cases and literature review.
abstract: Spiradenoma is a benign skin adnexal neoplasm that usually appears as a solitary nodule in any area of the body. There have been only 33 reports on malignant transformation of a benign eccrine spiradenoma since the first description by Dabska in 1972. Most cases have originated on a long-standing cutaneous lesion. These tumors can behave in an aggressive fashion, and some have led to the patient's death. We report 2 new cases of this rare neoplasm affecting 2 men, 92 and 72 years of age, comment on the clinical and pathologic features of our cases, and review the literature concerning this lesion.
authors.affiliation: Deparment of Pathology, Hospital General de Móstoles, Madrid, Spain. mgg10167@teleline.es
authors.forename: M J
authors.initials: MJ
authors.lastname: Fernández-Aceñero
authors.forename: F
authors.initials: F
authors.lastname: Manzarbeitia
authors.forename: M J
authors.initials: MJ
authors.lastname: Mestre de Juan
authors.forename: L
authors.initials: L
authors.lastname: Requena
mesh_terms: D006607:Adenoma, Sweat Gland / Q000175:diagnosis / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology*; D012720:Severity of Illness Index; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000175:diagnosis / Q000473:pathology*