Surfactant protein-A gene locus associated with recurrent otitis media.
Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.
Rämet
M
M
Department of Pediatrics, University Central Hospital, and Biocenter Oulu, University of Oulu, Oulu, Finland.
Löfgren
J
J
Alho
O P
OP
Hallman
M
M
D002648:Child; D002675:Child, Preschool; D002874:Chromosome Mapping; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007223:Infant; D037102:Lectins / Q000235:genetics*; D008297:Male; D010033:Otitis Media / Q000235:genetics*; D011510:Proteolipids / Q000235:genetics*; D037661:Pulmonary Surfactant-Associated Proteins; D011663:Pulmonary Surfactants / Q000235:genetics*; D012008:Recurrence
D037102:Lectins; D011510:Proteolipids; D037661:Pulmonary Surfactant-Associated Proteins; D011663:Pulmonary Surfactants