title: Successful treatment of MRSA mediastinitis after aortic arch replacement.
abstract: An aortic arch graft replacement was successfully performed for a true aneurysm on the distal aortic arch. However, Methicillin-resistant Staphylococcus aureus (MRSA) mediastinitis occurred after surgery. Following reoperation for debridement and irrigation of the mediastinal space, antibiotics were administered and continuous irrigation of mediastinal space with saline containing appropriate antibiotics and intermittently short duration irrigation with a large quantity of saline containing popidone-iodine were carried out with good results. This paper presents the successful treatment of mediastinitis after replacement of the aortic arch without removing the graft, followed by a brief review of the literature regarding infection of prostetic grafts for the thoracic aorta.
authors.affiliation: Department of Cardiovascular Surgery, Shizuoka General Hospital, Shizuoka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kaneda
authors.forename: M
authors.initials: M
authors.lastname: Aoshima
authors.forename: N
authors.initials: N
authors.lastname: Ishigami
authors.forename: J
authors.initials: J
authors.lastname: Iemura
authors.forename: T
authors.initials: T
authors.lastname: Matsumoto
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000382:microbiology* / Q000628:therapy*; D016106:Methicillin Resistance; D016459:Prosthesis-Related Infections / Q000382:microbiology / Q000628:therapy*; D013203:Staphylococcal Infections / Q000628:therapy*; D013211:Staphylococcus aureus / Q000187:drug effects; D007507:Therapeutic Irrigation
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local