A new 'spin' on neural stem cells?
The existence of neural stem cells in the adult brain was essentially denied until the last decade. Within the past ten years, considerable progress has been made in examining the fundamental properties of neural stem cells. Most recently there has been much interest in the identification and precise location of the adult neural stem cells in vivo. Studies examining the localization of neural stem cells are controversial and suggest two distinct locations within the adult brain: the ependymal layer lining the ventricles, and the subependymal layer immediately adjacent to the ependyma.
Morshead
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Department of Surgery, Division of Anatomy, University of Toronto, 1 Kings's College CircleMedical Science Building, Toronto, ON M5S 1A8, Canada.
van der Kooy
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D000328:Adult; D001921:Brain / Q000166:cytology* / Q000196:embryology*; D004805:Ependyma / Q000166:cytology / Q000502:physiology; D006801:Humans; D009474:Neurons / Q000502:physiology*; D013234:Stem Cells / Q000502:physiology*