title: Effect of breath holding on blood flow measurement using fast velocity encoded cine MRI.
abstract: Breath-hold MR measurement of cardiac output was compared with results from respiratory triggered MR acquisitions, since flow measurement during breath-holding may be different from physiological blood flow. Cardiac output during large lung volume breath-holding (4.47 +/- 0.63 l/min in the aorta and 4.53 +/- 0.59 l/min in the pulmonary artery) was significantly lower than that measured during normal breathing (6.09 +/- 0.49 l/min and 6.48 +/- 0.67 l/min, P < 0.01). In contrast, no significant difference was found between measurements conducted with small lung volume breath-holding (5.87 +/- 0.53 l/min and 6.41 +/- 0.75 l/min) and normal breathing. In conclusion, breath-hold MR flow measurement using small lung volume by shallow inspiration can provide a blood flow quantification that is close to physiological blood flow. Magn Reson Med 45:346-348, 2001.
authors.affiliation: Department of Radiology, Mie University School of Medicine, 2-174 Idobashi, Tsu, Mie 514-8507, Japan. sakuma@mri-gw.medic.mie-u.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Sakuma
authors.forename: N
authors.initials: N
authors.lastname: Kawada
authors.forename: H
authors.initials: H
authors.lastname: Kubo
authors.forename: Y
authors.initials: Y
authors.lastname: Nishide
authors.forename: K
authors.initials: K
authors.lastname: Takano
authors.forename: N
authors.initials: N
authors.lastname: Kato
authors.forename: K
authors.initials: K
authors.lastname: Takeda
mesh_terms: D000328:Adult; D001775:Blood Circulation / Q000502:physiology*; D002302:Cardiac Output / Q000502:physiology; D005260:Female; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D012143:Respiratory Physiological Phenomena