title: Evolution of adaptive immunity.
abstract: Antigen receptors and major histocompatibility molecules, key elements required for adaptive immunity, are first seen in jawed fish. So, how did they evolve and have they changed?
authors.affiliation: Department of Zoology, University of Aberdeen, Tillydrone Avenue, Aberdeen, AB24 2TZ.
authors.forename: C J
authors.initials: CJ
authors.lastname: Secombes
authors.forename: L
authors.initials: L
authors.lastname: Pilström
mesh_terms: D000818:Animals; D005075:Biological Evolution; D016207:Cytokines / Q000502:physiology; D006801:Humans; D007109:Immunity; D007143:Immunoglobulin Heavy Chains / Q000276:immunology; D007147:Immunoglobulin Light Chains / Q000276:immunology; D008285:Major Histocompatibility Complex; D011946:Receptors, Antigen / Q000276:immunology
chemical_list: D016207:Cytokines; D007143:Immunoglobulin Heavy Chains; D007147:Immunoglobulin Light Chains; D011946:Receptors, Antigen