title: Deciphering Campylobacter jejuni cell surface interactions from the genome sequence.
abstract: The completion of the Campylobacter jejuni genome sequence is a landmark in Campylobacter research. Discoveries directly arising from these data include the identification of a capsular polysaccharide, extensive capacity for phase variable gene expression and lipo-oligosaccharide structural phase variation. The recent identification of a unique system of general protein glycosylation in C. jejuni, a C. jejuni protein that is translocated into eukaryotic cells, and plasmid-encoded components of a putative type IV secretion system are likely to be significant in terms of the host-pathogen interaction.
authors.affiliation: Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK.
authors.forename: D
authors.initials: D
authors.lastname: Linton
authors.forename: A V
authors.initials: AV
authors.lastname: Karlyshev
authors.forename: B W
authors.initials: BW
authors.lastname: Wren
mesh_terms: D000940:Antigenic Variation; D000954:Antigens, Surface / Q000378:metabolism; D001426:Bacterial Proteins / Q000378:metabolism*; D016123:Campylobacter jejuni / Q000235:genetics* / Q000378:metabolism; D002473:Cell Wall / Q000378:metabolism; D005408:Flagellin / Q000378:metabolism; D016680:Genome, Bacterial; D006031:Glycosylation; D006801:Humans; D008070:Lipopolysaccharides / Q000378:metabolism
chemical_list: D000954:Antigens, Surface; D001426:Bacterial Proteins; D008070:Lipopolysaccharides; D005408:Flagellin