Dendritic arbor development and synaptogenesis.
In vivo studies indicate that synaptic activity promotes dendritic arbor elaboration at early stages of brain development. At later stages of development, synaptic activity stabilizes dendritic structure. The different roles of synaptic activity with respect to structural plasticity probably reflect the regulated spatiotemporal expression of key components within signaling pathways.
Cline
H T
HT
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA. Cline@cshl.org
D000818:Animals; D001921:Brain / Q000254:growth & development; D001923:Brain Chemistry / Q000502:physiology; D003712:Dendrites / Q000502:physiology*; D020558:GTP Phosphohydrolases / Q000502:physiology; D006801:Humans; D009420:Nervous System / Q000737:chemistry / Q000254:growth & development*; D013569:Synapses / Q000502:physiology*
D020558:GTP Phosphohydrolases