The tegument protein ppUL25 of human cytomegalovirus (CMV) is a major target antigen for the anti-CMV antibody response.
A viral protein of approximately 82 kDa is the only structural protein of human cytomegalovirus (CMV) that is strongly immunogenic during natural infection and the corresponding gene of which is still unknown. In this work, strong evidence is presented that this protein is the product of UL25.
Lazzarotto
Tiziana
T
Department of Clinical and Experimental Medicine, Division of Microbiology, Laboratory of Virology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy1.
Varani
Stefania
S
Department of Clinical and Experimental Medicine, Division of Microbiology, Laboratory of Virology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy1.
Gabrielli
Liliana
L
Department of Clinical and Experimental Medicine, Division of Microbiology, Laboratory of Virology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy1.
Pignatelli
Sara
S
Department of Clinical and Experimental Medicine, Division of Microbiology, Laboratory of Virology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy1.
Landini
Maria Paola
MP
Department of Clinical and Experimental Medicine, Division of Microbiology, Laboratory of Virology, University of Bologna, St Orsola General Hospital, Via Massarenti 9, 40138 Bologna, Italy1.
D000327:Adsorption; D000914:Antibodies, Viral / Q000276:immunology; D000956:Antigens, Viral / Q000737:chemistry / Q000276:immunology*; D001782:Blood Donors; D003587:Cytomegalovirus / Q000737:chemistry / Q000276:immunology*; D005260:Female; D006801:Humans; D007106:Immune Sera / Q000276:immunology; D016056:Immunodominant Epitopes / Q000737:chemistry / Q000276:immunology*; D008297:Male; D008970:Molecular Weight; D016377:Organ Transplantation; D011247:Pregnancy; D014764:Viral Proteins / Q000737:chemistry / Q000276:immunology*
D000914:Antibodies, Viral; D000956:Antigens, Viral; D007106:Immune Sera; D016056:Immunodominant Epitopes; C087088:UL25 protein, Cytomegalovirus; D014764:Viral Proteins