title: Transesophageal Echocardiography with Pathological Correlation in Severe Valvular Disease Associated with Fenfluramine-Phentermine.
abstract: We describe the case of severe diffuse multivalvular disease associated with fenfluramine-phentermine (Fen-Phen) in a 52-year-old patient who presented to the echocardiography laboratory for evaluation of a new heart murmur and ultimately required isolated aortic valve replacement. The patient was known to have a transthoracic echocardiogram 1 year before starting the diet pill combination that showed no significant valvular disease. Pathological evaluation of the excised aortic valve was consistent with that described with Fen-Phen use. Transesophageal echocardiography played an important role in defining unique features associated with the valvular disease and in intraoperative management of the patient.
authors.affiliation: Division of Cardiology, Montefiore Medical Center, 111 E. 210th St., Bronx, NY 10467-2490.
authors.forename: Judy R.
authors.initials: JR
authors.lastname: Mangion
authors.forename: Ahmad A.
authors.initials: AA
authors.lastname: Habboub
authors.forename: Brinda R.
authors.initials: BR
authors.lastname: Kamat
authors.forename: Stanley K. C.
authors.initials: SK
authors.lastname: Tam