title: Stability of cefotaxime sodium in solid state.
abstract: The influence of temperature and relative humidity on the stability of cefotaxime sodium in the solid state was investigated. Changes in the concentration of cefotaxime sodium were followed by a HPLC method with UV detection. The kinetic and thermodynamic parameters of the decomposition reaction were calculated.
authors.affiliation: Department of Pharmaceutical Chemistry, University of Medical Sciences, Poznań, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Zajac
authors.forename: W
authors.initials: W
authors.lastname: Musiał
authors.forename: L
authors.initials: L
authors.lastname: Pawłowski
mesh_terms: D002439:Cefotaxime / Q000737:chemistry*; D002511:Cephalosporins / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D006813:Humidity; D013056:Spectrophotometry, Ultraviolet; D013696:Temperature; D013816:Thermodynamics
chemical_list: D002511:Cephalosporins; D002439:Cefotaxime