title: New calixarene-bonded stationary phases in high-performance liquid chromatography: comparative studies on the retention behavior and on influences of the eluent.
abstract: The chromatographic behavior of six calixarene-bonded stationary phases is reported. Varying analyte selectivities (i.e., for phenols, substituted aromatics, polycyclic aromatic hydrocarbons, barbituric acid derivatives, xanthines) exist as a function of the ring-size of the calix[n]arenes (n=4, 6, 8) and the substitution at the "upper rim" with para-tert.-butyl groups. Although eluents with unusually high proportions of water were used, a comparison with conventional reversed-phase (RP) columns shows a predominantly reversed-phase character with remarkable selectivities of these phases. The influences of several organic solvents on retention variations of solutes are compared for RP-C18, phenyl and calixarene phases.
authors.affiliation: Institute of Pharmacy, Pharmaceutical/Medicinal Chemistry, Ernst-Moritz-Arndt-University of Greifswald, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Sokoliess
authors.forename: U
authors.initials: U
authors.lastname: Menyes
authors.forename: U
authors.initials: U
authors.lastname: Roth
authors.forename: T
authors.initials: T
authors.lastname: Jira
mesh_terms: D047250:Calixarenes; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D046911:Macromolecular Substances; D010672:Phenytoin / Q000302:isolation & purification; D011083:Polycyclic Compounds / Q000302:isolation & purification; D011324:Primidone / Q000302:isolation & purification
chemical_list: D046911:Macromolecular Substances; D011083:Polycyclic Compounds; D047250:Calixarenes; D011324:Primidone; D010672:Phenytoin