Selective permeabilization of infected host cells with pore-forming proteins provides a novel tool to study protein synthesis and viability of the intracellular apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii.
Baumeister
S
S
FB Biologie/Zoologie, Philipps Universität Marburg, 35032 Marburg, Germany.
Paprotka
K
K
Bhakdi
S
S
Lingelbach
K
K
D000818:Animals; D001426:Bacterial Proteins; D002463:Cell Membrane Permeability / Q000187:drug effects*; D004912:Erythrocytes / Q000469:parasitology; D006801:Humans; D008264:Macrophages / Q000469:parasitology; D016778:Malaria, Falciparum / Q000469:parasitology; D010963:Plasmodium falciparum / Q000254:growth & development* / Q000378:metabolism; D015800:Protozoan Proteins / Q000096:biosynthesis*; D012276:Ricin / Q000494:pharmacology; D013301:Streptolysins / Q000494:pharmacology*; D014122:Toxoplasma / Q000254:growth & development* / Q000378:metabolism; D014123:Toxoplasmosis / Q000469:parasitology
D001426:Bacterial Proteins; D015800:Protozoan Proteins; D013301:Streptolysins; C025964:streptolysin O; D012276:Ricin