[The clinical study of immune factors relative to Menière's disease].
It was investigated that the clinical unspecialized immunological factors and special immune reaction against to inner ear antigens relate with the cause of Meniere's disease. Every of the relative immune tests and special humoral and cellular immune reaction tests were proceeded in the breaking out and intermittent period of Meniere's disease patients, and the normal controls. The levels of IgG and C3 in serum and unspecialized lymphocyte blastogenesis increased, and positive of circular immune compound and antibody against cellular nucleus, and special humoral and cellular immune reaction against inner ear antigens during the breaking out period of the patients. The element of inner ear autoimmune could play an important role in the pathogenical mechanism of some patients with Meniere's disease.
Tan
C
C
Department of Otolaryngology, Affiliated Hospital of Nanjing, Railway Medical College, Nanjing 210009.
Cao
Y
Y
Liu
H
H
D000293:Adolescent; D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D003176:Complement C3 / Q000378:metabolism*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008213:Lymphocyte Activation; D008297:Male; D008575:Meniere Disease / Q000276:immunology*; D008875:Middle Aged
D000974:Antibodies, Antinuclear; D003176:Complement C3; D007074:Immunoglobulin G