Characterization of the mouse Cblc/Cbl3 gene.
The mouse Cblc/Cbl3 gene was cloned and characterized. It comprises 12 exons and encodes a putative protein of 496 amino acid residues which shares an overall 67% identity with its human ortholog; it also shares 70% of amino acid identity with mouse CBL over their conserved SH2 and Ring finger domains. Mouse Cblc mRNA is expressed in embryo and adult tissues and has a rather ubiquitous distribution.
Fiore
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Laboratoire d'Oncologie Moléculaire, U.119 Inserm, IFR57, 27 Boulevard Leï Roure, 13009 Marseille, France.
Ollendorff
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Birnbaum
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D000595:Amino Acid Sequence; D000818:Animals; D003001:Cloning, Molecular; D017124:Conserved Sequence; D005091:Exons; D015870:Gene Expression; D006801:Humans; D007438:Introns; D051379:Mice; D008969:Molecular Sequence Data; D050722:Oncogene Protein v-cbl; D009928:Organ Specificity; D050721:Proto-Oncogene Proteins c-cbl; D015682:Retroviridae Proteins, Oncogenic / Q000737:chemistry / Q000235:genetics*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D016335:Zinc Fingers; D018909:src Homology Domains
D050722:Oncogene Protein v-cbl; D015682:Retroviridae Proteins, Oncogenic; D050721:Proto-Oncogene Proteins c-cbl; C422087:Cblc protein, mouse