title: [Prenatal diagnois of uropathies. Ten case reports].
abstract: Obstructive uropathies are a frequent cause of child renal failure. The prenatal diagnosis of such abnomalities should lead to appropriate management.
  
  
  OBJECTIVE
  To evaluate the interest of ultrasonographic prenatal diagnosis of urinary tract malformations.
  
  
  METHODS
  Retrospective study of 10 cases of urinary tract malformations diagnosed in utero. The mean age of the patients was 34.9 years and the mean gestational age at the prenatal diagnosis was 28.2 weeks of amenorrhea. The abnormalities diagnosed were: 2 cases of ureteropelvic junction obstruction, 3 cases of posterior urethral valves and 5 cases of mild hydronephrosis. The fetal karyotype, realised in 8 cases, was normal. In one case the urinary abnormalities was part of a multiple malformation syndrome and led to the termination of the pregnancy. 7 cases had a post-natal follow-up: 5 had a surgical management and two new borns had transient pyelectasies. The prediction of postnatal renal function is made by ultrasonographic appearance of the kidney and the amniotic fluid. Although the analysis of fetal urine for the assessment of renal function leads to conflicting results, it seems that sodium and beta-2 microglobulin urinary rates provide useful informations.
authors.affiliation: Service de gynécologie-obstétrique A, EPS Charles Nicolle, Tunis.
authors.forename: K
authors.initials: K
authors.lastname: Terras
authors.forename: A
authors.initials: A
authors.lastname: Koubaa
authors.forename: B
authors.initials: B
authors.lastname: Ben Ayed
authors.forename: T
authors.initials: T
authors.lastname: Makhlouf
authors.forename: A
authors.initials: A
authors.lastname: Chéchia
authors.forename: R
authors.initials: R
authors.lastname: Zribi
mesh_terms: D000328:Adult; D000465:Algorithms; D003663:Decision Trees; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000652:urine; D005865:Gestational Age; D006801:Humans; D006869:Hydronephrosis / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000652:urine; D007621:Karyotyping; D011237:Predictive Value of Tests; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012189:Retrospective Studies; D012964:Sodium / Q000652:urine; D016216:Ultrasonography, Prenatal / Q000379:methods*; D001748:Urinary Bladder Neck Obstruction / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000652:urine; D014551:Urinary Tract / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D001613:beta 2-Microglobulin / Q000652:urine
chemical_list: D001613:beta 2-Microglobulin; D012964:Sodium