title: Does massively parallel transcriptome analysis signify the end of cancer histopathology as we know it?
abstract: Transcriptional analysis of all the genes expressed by breast tumors has provided the first steps towards defining a molecular signature for the disease, and might ultimately make conventional diagnostic techniques obsolete.
authors.affiliation: Department of Oncology, University of Cambridge, Wellcome Trust/MRC Building, Addenbrookes Hospital, Cambridge CB2 2XY,UK. saparici@hgmp.mrc.ac.uk
authors.forename: S A
authors.initials: SA
authors.lastname: Aparicio
authors.forename: C
authors.initials: C
authors.lastname: Caldas
authors.forename: B
authors.initials: B
authors.lastname: Ponder
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics; D001943:Breast Neoplasms / Q000145:classification / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology*; D020224:Expressed Sequence Tags; D020869:Gene Expression Profiling / Q000639:trends; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D009367:Neoplasm Staging; D020411:Oligonucleotide Array Sequence Analysis / Q000639:trends; D012334:RNA, Neoplasm / Q000032:analysis / Q000235:genetics
chemical_list: D014408:Biomarkers, Tumor; D012334:RNA, Neoplasm