title: On the IVUS plaque volume error in coronary arteries when neglecting curvature.
abstract: Plaque volume determined by common linear 3-D IVUS analysis systems will show under- or overestimation in curved vessel segments because these systems approximate the true 3-D transducer pull-back trajectory by a straight line. We developed a mathematical model that showed that the error is primarily dependent on the curvature of the pull-back trajectory and not on vessel tortuosity. Furthermore, we measured this error in vivo in the coronary arteries of 15 patients, comparing the plaque volume using a true 3-D reconstruction method with that of the linear approach. The in vivo plaque volume error ranged from 2.3% to -1.2% for 15 coronary segments with lengths ranging from 38.8 to 89.1 mm (62.2 +/- 13 mm). The volume error introduced by linear 3-D IVUS analysis systems is dependent on the curvature of the pull-back trajectory. The error measured in vivo was small and inversely related to segment length.
authors.affiliation: Department of Cardiology, Thoraxcenter, University Hospital Rotterdam-Dijkzigt, Rotterdam, The Netherlands. schuurbiers@tch.fgg.eur.nl
authors.forename: J C
authors.initials: JC
authors.lastname: Schuurbiers
authors.forename: C
authors.initials: C
authors.lastname: von Birgelen
authors.forename: J J
authors.initials: JJ
authors.lastname: Wentzel
authors.forename: N
authors.initials: N
authors.lastname: Bom
authors.forename: P W
authors.initials: PW
authors.lastname: Serruys
authors.forename: P J
authors.initials: PJ
authors.lastname: de Feyter
authors.forename: C J
authors.initials: CJ
authors.lastname: Slager
mesh_terms: D001158:Arteries / Q000000981:diagnostic imaging; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D003951:Diagnostic Errors; D006801:Humans; D021621:Imaging, Three-Dimensional; D008962:Models, Theoretical; D019047:Phantoms, Imaging; D018084:Ultrasonography, Interventional