Coordinating cell proliferation and differentiation.
Cell proliferation and differentiation are highly coordinated processes during development. Recent studies have revealed that this coordination may result from dual functions residing in the central regulators of proliferation, allowing them to also regulate differentiation. Studies have also shown that some terminally differentiated cells can be made to divide beyond their normal capacity.
Zhu
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Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA. lizhu@aecom.yu.edu
Skoultchi
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D000818:Animals; D002454:Cell Differentiation / Q000235:genetics* / Q000502:physiology; D002455:Cell Division / Q000235:genetics / Q000502:physiology; D018844:Cyclin-Dependent Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D018816:Genes, cdc / Q000502:physiology*; D006801:Humans
D018844:Cyclin-Dependent Kinases