Abnormal cognition and behavior in preterm neonates linked to smaller brain volumes.
Volumetric measurements of the brain regions in eight-year-old children indicate that the poor cognitive and behavioral outcomes noted in ex-preterm neonates are associated with reduced volumes of specific regions in the brain. Recent literature suggests that this reduction might result from enhanced apoptosis or excitotoxic damage to highly susceptible immature neurons.
Bhutta
A T
AT
Dept of Pediatrics, University of Arkansas for Medical Sciences, 800 Marshall Street, Little Rock, AR 72202-3591, USA.
Anand
K J
KJ
D000328:Adult; D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000209:etiology*; D004453:Echoencephalography; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000523:psychology*; D009474:Neurons / Q000502:physiology