title: Oral ulcers caused by hydroxyurea.
abstract: We present a case of oral ulceration in a patient with essential thrombocythaemia, that proved to be secondary to treatment with hydroxyurea. This complication has not yet been reported in the ENT literature. Hydroxyurea should be considered as a possible cause of persistent oral ulceration in patients with haematological conditions. It should be noted that the onset of this complication is not related to the dose and duration of therapy.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Sunderland Royal Hospital, Sunderland, UK. vinidpa@hotmail.com
authors.forename: V
authors.initials: V
authors.lastname: Paleri
authors.forename: L
authors.initials: L
authors.lastname: Lindsey
mesh_terms: D000368:Aged; D000740:Anemia / Q000139:chemically induced; D006801:Humans; D006918:Hydroxyurea / Q000009:adverse effects*; D008297:Male; D009061:Mouth Mucosa; D019384:Nucleic Acid Synthesis Inhibitors / Q000009:adverse effects*; D019226:Oral Ulcer / Q000139:chemically induced*; D013280:Stomatitis / Q000139:chemically induced*; D013922:Thrombocytosis / Q000188:drug therapy*
chemical_list: D019384:Nucleic Acid Synthesis Inhibitors; D006918:Hydroxyurea