An arrow hits the Wnt signaling pathway.
A recent series of papers in Nature shows that low-density lipoprotein receptor-related protein family members play a role in transduction of Wnt signals. These findings, in addition to other work from the past two years, have important implications for the role of Wnts in neural development.
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Neurodevelopmental Disorders Laboratory, Dept of Neurology, Room S256C, 513 Parnassus Avenue, University of California, San Francisco, CA 94143, USA. samuelp@itsa.ucsf.edu
D000818:Animals; D002540:Cerebral Cortex / Q000254:growth & development / Q000378:metabolism*; D004330:Drosophila / Q000235:genetics; D006801:Humans; D009154:Mutation / Q000502:physiology; D011518:Proto-Oncogene Proteins / Q000502:physiology*; D011973:Receptors, LDL / Q000378:metabolism / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D051153:Wnt Proteins; D029961:Zebrafish Proteins
D011518:Proto-Oncogene Proteins; D011973:Receptors, LDL; D051153:Wnt Proteins; D029961:Zebrafish Proteins