title: Diuresis in the housefly (Musca domestica) and its control by neuropeptides.
abstract: Diuresis was studied in vivo by measuring the loss of tritiated water. The basal rate of water loss (5 nl/min) represents respiratory and cuticular losses, whereas higher rates reflect urine output, which reaches 20 nl/min after injection of 1 microl distilled water. This response to hypervolemia involves release of a diuretic hormone(s) into the hemolymph. However, housefly diuretic peptides increased urine output to a maximum of only 7 nl/min, and higher rates may require fluid reabsorption from the hindgut to be reduced. Diuresis is partially blocked by injected anti-muscakinin antibodies, providing evidence of a hormonal function for this insect myokinin.
authors.affiliation: Department of Biology, Birkbeck College, London, United Kingdom. g.coast@bbk.ac.uk
authors.forename: G M
authors.initials: GM
authors.lastname: Coast
mesh_terms: D000818:Animals; D004231:Diuresis / Q000502:physiology*; D006793:Houseflies / Q000502:physiology*; D009479:Neuropeptides / Q000502:physiology*
chemical_list: D009479:Neuropeptides