title: New Heck-type reaction applied to the synthesis of protoporphyrin-IX derivatives.
abstract: [reaction: se text] A new Heck-type reaction under catalysis by Pd for obtaining polysubstituted arylvinylydene derivatives of porphyrin systems is reported. The coupling between the Zn(II)-protoporphyrin-IX dimethylester Zn-2 and several bromo-aryl and iodo-aryl compounds in the presence of a new Pd catalyst has been studied. This coupling reaction, although providing moderate regioselectivity, gives quantitative conversion.
authors.affiliation: Departament de Química Orgànica and Departament de Química Inorgànica, Universitat de Barcelona, Martí i Franqués 1-11, E-08028 Barcelona, Catalunya, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Castella
authors.forename: F
authors.initials: F
authors.lastname: Calahorra
authors.forename: D
authors.initials: D
authors.lastname: Sainz
authors.forename: D
authors.initials: D
authors.lastname: Velasco
mesh_terms: D002384:Catalysis; D002855:Chromatography, Thin Layer; D006427:Hemin / Q000737:chemistry; D006846:Hydrocarbons, Halogenated / Q000737:chemistry; D008665:Metalloporphyrins / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium; D011166:Porphyrins; D011524:Protoporphyrins / Q000138:chemical synthesis* / Q000737:chemistry; D014753:Vinyl Compounds / Q000737:chemistry; D015032:Zinc
chemical_list: D006846:Hydrocarbons, Halogenated; D008665:Metalloporphyrins; D011166:Porphyrins; D011524:Protoporphyrins; D014753:Vinyl Compounds; D010165:Palladium; D006427:Hemin; C028025:protoporphyrin IX; D015032:Zinc