Plasmablastic lymphoma of the lung: report of a unique case and review of the literature.
Non-Hodgkin lymphomas associated with acquired immunodeficiency syndrome are heterogeneous. Recently, a novel subtype of non-Hodgkin lymphoma occurring mostly in patients with acquired immunodeficiency syndrome has been described and designated as plasmablastic lymphoma. The histomorphologic and immunophenotypic findings of this distinct subtype of non-Hodgkin lymphoma have been characterized previously. Most patients present with oral cavity involvement. We report a case of plasmablastic lymphoma presenting as a lung tumor. To our knowledge, this is the first case report of this unusual subtype of diffuse large B-cell lymphoma in this location.
Lin
Y
Y
Department of Pathology, University of Iowa College of Medicine, Iowa City, USA.
Rodrigues
G D
GD
Turner
J F
JF
Vasef
M A
MA
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000911:Antibodies, Monoclonal; D004279:DNA, Viral / Q000032:analysis; D004854:Herpesvirus 4, Human / Q000235:genetics; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D017403:In Situ Hybridization; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology / Q000821:virology; D016483:Lymphoma, AIDS-Related / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology / Q000821:virology; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008562:Membrane Glycoproteins / Q000032:analysis; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology; D011509:Proteoglycans / Q000032:analysis; D053667:Syndecans
D000911:Antibodies, Monoclonal; D004279:DNA, Viral; D008562:Membrane Glycoproteins; D011509:Proteoglycans; D053667:Syndecans; C100347:VS38 monoclonal antibody