A novel germline in frame deletion (4128del3) of the BRCA2 gene detected in a breast/ovarian cancer family with fallopian tube and brain tumors identified in the north of France.
Demange
L
L
Tumor Biology Laboratory, Department of Genetic Oncology / INSERM EPI 9939, INSERM U 119, Paoli-Calmettes Institute, Marseille, France.
Noguchi
T
T
Sauvan
R
R
Moyal-Amsellem
N
N
Birnbaum
D
D
Eisinger
F
F
Sobol
H
H
D024682:BRCA2 Protein; D001483:Base Sequence; D001932:Brain Neoplasms / Q000150:complications*; D001943:Breast Neoplasms / Q000150:complications / Q000235:genetics*; D004252:DNA Mutational Analysis; D004273:DNA, Neoplasm / Q000737:chemistry / Q000235:genetics; D005185:Fallopian Tube Neoplasms / Q000150:complications*; D005192:Family Health; D005260:Female; D005602:France; D018095:Germ-Line Mutation; D006801:Humans; D009363:Neoplasm Proteins / Q000235:genetics*; D010051:Ovarian Neoplasms / Q000150:complications / Q000235:genetics*; D017384:Sequence Deletion; D014157:Transcription Factors / Q000235:genetics*
D024682:BRCA2 Protein; D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; D014157:Transcription Factors