Constitutive expression of c-myb mRNA in the adult rat brain.
In this study, we demonstrated the c-myb mRNA expression in the adult rat brain using an in situ hybridization technique. We found c-myb mRNA signals in the various regions of the forebrain and midbrain including the cerebral cortex, thalamus, hippocampus, hypothalamus, superior and inferior colliculi and central gray. In the cerebellum, a diffuse signal was found in the granular layer while some positive cells were detected in the molecular layer as well. In addition, a number of cells showed intense signals in many nuclei of the medulla oblongata. The constitutive expression of c-myb mRNA in the different kinds of neural cells suggests that this gene might be involved in the normal function of these neurons.
Shin
D H
DH
Department of Anatomy, Dankook University College of Medicine, Chonan, South Korea.
Lee
H W
HW
Jeon
G S
GS
Lee
H Y
HY
Lee
K H
KH
Cho
S S
SS
D000818:Animals; D001921:Brain / Q000502:physiology*; D020570:Genes, myb; D009474:Neurons / Q000502:physiology; D009928:Organ Specificity; D016548:Prosencephalon / Q000502:physiology; D020598:Proto-Oncogene Proteins c-myb / Q000235:genetics*; D012333:RNA, Messenger / Q000032:analysis; D051381:Rats; D017207:Rats, Sprague-Dawley; D013477:Superior Colliculi / Q000502:physiology; D014158:Transcription, Genetic
D020598:Proto-Oncogene Proteins c-myb; D012333:RNA, Messenger