title: Effect of amitriptyline on daily variations in cell composition of immune organs in rats with experimental desynchronosis.
abstract: We studied the effects of amitriptyline (preparation stimulating melatonin synthesis in the pineal gland) on daily variations of cell composition in immune organs of Wistar rats with experimental desynchronosis. Amitriptyline administered in the evening restored the daily dynamics of the number of thymus cells.
authors.affiliation: Institute of Clinical and Experimental Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia.
authors.forename: G I
authors.initials: GI
authors.lastname: Litvinenko
authors.forename: L V
authors.initials: LV
authors.lastname: Verbitskaya
authors.forename: L V
authors.initials: LV
authors.lastname: Taradanova
authors.forename: E V
authors.initials: EV
authors.lastname: Mel'nikova
authors.forename: M V
authors.initials: MV
authors.lastname: Tenditnik
authors.forename: A V
authors.initials: AV
authors.lastname: Shurlygina
authors.forename: V A
authors.initials: VA
authors.lastname: Trufakin
mesh_terms: D000639:Amitriptyline / Q000494:pharmacology*; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D021081:Chronobiology Disorders / Q000188:drug therapy*; D002940:Circadian Rhythm / Q000187:drug effects*; D004195:Disease Models, Animal; D007958:Leukocyte Count; D008027:Light; D018655:Lymphocyte Count; D008221:Lymphoid Tissue / Q000166:cytology / Q000187:drug effects*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000166:cytology / Q000187:drug effects
chemical_list: D000928:Antidepressive Agents; D000639:Amitriptyline