title: Development of endocrine and lymphocytopoietic functions of the thymus in human embryogenesis.
abstract: The endocrine function of the thymus develops earlier than lymphocytopoietic. Thymalin is produced by epithelial cells in the thymus primordium. It is released into the blood and regulates differentiation of T lymphocytes in the liver, the initial hemopoietic organ. The hormonal and lymphopoietic functions of human thymus are united on weeks 7.5-8 of embryonic life.
authors.affiliation: Laboratory of Embryonal Histogenesis, Institute of Human Morphology, Moscow.
authors.forename: Z S
authors.initials: ZS
authors.lastname: Khlystova
authors.forename: I I
authors.initials: II
authors.lastname: Kalinina
authors.forename: S P
authors.initials: SP
authors.lastname: Shmeleva
authors.forename: O P
authors.initials: OP
authors.lastname: Ryabchikov
mesh_terms: D004847:Epithelial Cells / Q000378:metabolism; D005260:Female; D022781:Hepatocytes / Q000648:ultrastructure; D006801:Humans; D008099:Liver / Q000166:cytology / Q000196:embryology* / Q000502:physiology*; D008214:Lymphocytes / Q000502:physiology; D013950:Thymus Gland / Q000196:embryology* / Q000276:immunology*; D013951:Thymus Hormones / Q000378:metabolism
chemical_list: D013951:Thymus Hormones; C032805:thymalin