title: Warthin's tumour in the parotid gland (an inflammatory or a neoplastic disease?).
abstract: Warthin's tumour has always been considered a peculiar neoplasm with specific anatomico-pathological characteristics. In this study we argue that it should not be considered a true neoplasm but simply an inflammatory process which is triggered by the indiscriminate use of tobacco and involves the parotid duct. In the 10 cases treated in our department, Warthin's tumour has predominantly affected males (9:1) and heavy smokers. Our treatment of choice has been enucleoresection. The results have been satisfactory, with no complications such as salivary fistula or permanent lesions of the facial nerve. In two subjects, treated by enucleoresection, there was a pleomorphic adenoma: in one on the same side as previous surgery performed two years earlier and, in the second, in the contralateral gland 4 years after surgery. Both patients, who underwent total parotidectomy, recovered perfectly without complications. Smoking appears to be involved in the development of Warthin's tumour and might be regarded as an inflammatory reaction to smoking or to ionising radiation. Ultrasound and FNAB are necessary for planning the correct surgical strategy, and enucleoresection, in our opinion, is the treatment of choice.
authors.affiliation: Servizio di Chirurgia Generale e Tecniche Chirurgiche Speciali, Istituto di Clinica Chirurgica d'Urgenza, II Università degli Studi di Napoli.
authors.forename: A
authors.initials: A
authors.lastname: Cennamo
authors.forename: A
authors.initials: A
authors.lastname: Falsetto
authors.forename: G
authors.initials: G
authors.lastname: Gallo
authors.forename: M
authors.initials: M
authors.lastname: Lanna
authors.forename: G
authors.initials: G
authors.lastname: Calleri
authors.forename: D
authors.initials: D
authors.lastname: Di Giacomo
mesh_terms: D000235:Adenolymphoma / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000175:diagnosis*; D010309:Parotitis / Q000175:diagnosis