Neurological symptoms in patients whose cerebrospinal fluid is culture- and/or polymerase chain reaction-positive for Mycoplasma pneumoniae.
We describe 13 patients with neurological signs and symptoms associated with Mycoplasma pneumoniae infection. M. pneumoniae was isolated from the cerebrospinal fluid (CSF) of 9 patients: 5 with meningoencephalitis, 2 with meningitis, and 1 with cerebrovascular infarction. One patient had headache and difficulties with concentration and thinking for 1 month after the acute infection. M. pneumoniae was detected, by means of PCR, in the CSF of 4 patients with negative culture results. Two had epileptic seizures, 1 had blurred vision as a consequence of edema of the optic disk, and 1 had peripheral nerve neuropathy.
Socan
M
M
Department of Infectious Diseases, University Medical Center, University of Ljubljana, Ljubljana, Slovenia. maja.socan@gov.si
Ravnik
I
I
Bencina
D
D
Dovc
P
P
Zakotnik
B
B
Jazbec
J
J
D000293:Adolescent; D000328:Adult; D001431:Bacteriological Techniques; D002544:Cerebral Infarction / Q000382:microbiology; D002648:Child; D004279:DNA, Viral / Q000032:analysis; D004827:Epilepsy / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000382:microbiology; D008590:Meningoencephalitis / Q000382:microbiology; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification*; D009422:Nervous System Diseases / Q000134:cerebrospinal fluid / Q000382:microbiology*; D010523:Peripheral Nervous System Diseases / Q000382:microbiology; D011019:Pneumonia, Mycoplasma / Q000134:cerebrospinal fluid / Q000150:complications*; D016133:Polymerase Chain Reaction
D004279:DNA, Viral