title: Estimation of postmortem interval. Temperature-correction of extracellular abdominal impedance during the first 21 days of death.
abstract: Extracellular impedance of the intact abdomen of rats increased from 79.0+/-7.4Omega, 1h postmortem (i.e. 0.04 day), to 130.5+/-14.4Omega at postmortem interval (PMI)=1 day. Impedance then decreased with time, reaching 64.2+/-9.9Omega at PMI=21 days. The time taken for mean abdominal impedance to decrease below the value at PMI=0.04 day averaged 16 days. It is therefore impossible, using extracellular abdominal impedance alone, to distinguish (in terms of interpolating PMI) between numerically equal impedances on the rising and falling phases of curves depicting impedance as a function of PMI. Correction of measured impedances to their theoretically-predicted values at an arbitrarily chosen temperature of 40 degrees C appreciably diminished the magnitude of the increase in impedance following death. Thus, temperature-corrected abdominal impedance increased from 56.2+/-4.8Omega at PMI=0.04 day to 59.5+/-6.2Omega at PMI=1 day. Impedance then decreased, reaching 29.2+/-4.1Omega at PMI=21 days. The time taken for mean, temperature-corrected abdominal impedance to decrease below the value at PMI=0.04 day averaged 3 days (as opposed to 16 days (see above) in the absence of temperature-correction). These findings are believed to improve the usefulness of extracellular abdominal impedance as a potential tool for estimation of postmortem interval.
authors.affiliation: Department of Physiology, Faculty of Health Sciences, Medical School Observatory, University of Cape Town, 7925, Cape Town, South Africa. dquerido@curie.uct.ac.za
authors.forename: D
authors.initials: D
authors.lastname: Querido
authors.forename: M R
authors.initials: MR
authors.lastname: Phillips
mesh_terms: D000005:Abdomen / Q000502:physiology*; D001344:Autopsy / Q000379:methods* / Q000592:standards; D015982:Bias; D001831:Body Temperature / Q000502:physiology*; D015986:Confounding Factors, Epidemiologic; D017097:Electric Impedance; D023421:Models, Animal; D008991:Monitoring, Physiologic / Q000379:methods / Q000592:standards; D011180:Postmortem Changes; D011237:Predictive Value of Tests; D013997:Time Factors