Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
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The Wolfson Institute for Biomedical Research, Cruciform Building, Gower Street, London WC1E 6AE, United Kingdom.
Madge
D J
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Mulla
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Riddall
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D000690:Amyotrophic Lateral Sclerosis / Q000188:drug therapy; D000700:Analgesics / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000927:Anticonvulsants / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D004827:Epilepsy / Q000188:drug therapy / Q000235:genetics; D006801:Humans; D015640:Ion Channel Gating; D008958:Models, Molecular; D009154:Mutation; D009419:Nerve Tissue Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D018696:Neuroprotective Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D011485:Protein Binding; D026941:Sodium Channel Blockers; D015222:Sodium Channels / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D020521:Stroke / Q000188:drug therapy
D000700:Analgesics; D000927:Anticonvulsants; D009419:Nerve Tissue Proteins; D018696:Neuroprotective Agents; D026941:Sodium Channel Blockers; D015222:Sodium Channels