title: [Pathological analysis and clinical importance of invasion and neck nodal metastasis in squamous cell carcinoma of the tongue].
abstract: To determine the absolute and relative of histopathological parameters and conventional indicators in correlation with invasion and nodal metastasis, we performed both univariate and multivariate statistical analysis in 92 patients with squamous cell carcinoma of the tongue by spss/pc+ statistical system. Mode of invasion (MI) and peritumoral lymphocytic infiltrating density (PLID) were significant and independent factors by multivariate analysis (P = 0.000, P = 0.009 respectively), although univariate analysis showed that MI, PLID, T-stage and Grading were significantly associated with nodal metastasis. A correlation exists only between T-stage and MI by multivariate statistical test (P = 0.045), while, PLID, T-stage and Grading were significant parameters by univariate analysis. A highly dense PLI around cancer nest was observed which blocked nest from tissue and capillary lymph vessels.
authors.affiliation: Department of Oral Maxillofacial Surgery, Frist Clinical College, China Medical University, Shenyang 110001.
authors.forename: L
authors.initials: L
authors.lastname: Lu
authors.forename: C
authors.initials: C
authors.lastname: Wang
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011379:Prognosis; D014062:Tongue Neoplasms / Q000473:pathology*