title: Partial unilateral lentiginosis with ocular involvement.
abstract: Partial unilateral lentiginosis (PUL) is an unusual pigmentary disorder characterized by numerous lentigines grouped within an area of normal skin; the pigmented macules are often in a segmental distribution with a sharp demarcation at the midline. We report the first case of ocular involvement in a patient with this diagnosis. The patient, a 30-year-old Peruvian woman, had multiple brown macules on the left upper face in primarily a V1 and V2 distribution with a sharp demarcation at the midline of the forehead. The lesions first appeared near the hairline when she was 5 years of age, and then began to extend onto the face. She also had a discrete area of brown pigmentation on the left lateral bulbar conjunctiva. Because the patient had been previously diagnosed by several dermatologists as having either a speckled lentiginous nevus or a nevus of Ota, we draw attention to the entity PUL and the possibility of ocular involvement.
authors.affiliation: Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut 06520, USA. votavajr@biomed.med.yale.edu
authors.forename: J V
authors.initials: JV
authors.lastname: Schaffer
authors.forename: R
authors.initials: R
authors.lastname: Lazova
authors.forename: J L
authors.initials: JL
authors.lastname: Bolognia
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D003229:Conjunctival Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007911:Lentigo / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008991:Monitoring, Physiologic; D009507:Nevus of Ota / Q000175:diagnosis* / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology