title: Disseminated Mycobacterium abscessus infection manifesting as fever of unknown origin and intra-abdominal lymphadenitis: case report and literature review.
abstract: Mycobacterium abscessus is a rapidly growing mycobacterium found in soil and water throughout the world. Disease in immunocompetent patients usually consists of localized skin and soft tissue infections. In contrast, disseminated disease is uncommon, usually presents with rash, and almost always occurs in an immunocompromised host. We describe an unusual case of disseminated M. abscessus infection manifesting as fever of unknown origin and intra-abdominal lymphadenitis, but without rash. Our patient responded well to amikacin and clarithromycin therapy. We also review the literature related to the diagnosis and management of this uncommon disease.
authors.affiliation: Division of General Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. mueller.paul@mayo.edu
authors.forename: P S
authors.initials: PS
authors.lastname: Mueller
authors.forename: R S
authors.initials: RS
authors.lastname: Edson
mesh_terms: D000368:Aged; D000583:Amikacin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017291:Clarithromycin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005076:Exanthema; D005335:Fever of Unknown Origin / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D016867:Immunocompromised Host; D008198:Lymph Nodes / Q000382:microbiology / Q000473:pathology; D008199:Lymphadenitis / Q000175:diagnosis / Q000382:microbiology; D008297:Male; D009161:Mycobacterium / Q000302:isolation & purification / Q000472:pathogenicity*; D009164:Mycobacterium Infections / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D000583:Amikacin; D017291:Clarithromycin