Prospects for vaccines to protect against AIDS, tuberculosis, and malaria.
Given the scope of the worldwide health problems caused by the acquired immunodeficiency syndrome, tuberculosis, and malaria, it is imperative that vaccines be developed to prevent these infections. Recent advances in the understanding of these diseases suggest that T-lymphocyte-mediated immunity is important in containing these infections. The application of novel vaccine technologies for eliciting this type of immunity promises to provide successful vaccines for controlling the spread of these deadly infections.
Letvin
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NL
Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, 41 Avenue of Louis Pasteur, Research East 113, Boston, MA 02115, USA. nletvin@caregroup.harvard.edu
Bloom
B R
BR
Hoffman
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SL
D016915:AIDS Vaccines; D000163:Acquired Immunodeficiency Syndrome / Q000517:prevention & control; D000818:Animals; D001500:BCG Vaccine; D017281:Cost of Illness; D005544:Forecasting; D006801:Humans; D008288:Malaria / Q000517:prevention & control; D017780:Malaria Vaccines; D012106:Research / Q000639:trends*; D014376:Tuberculosis / Q000517:prevention & control
D016915:AIDS Vaccines; D001500:BCG Vaccine; D017780:Malaria Vaccines