Allgrove syndrome in adulthood.
A 35-year-old man with a past history of achalasia developed progressive spastic tetraparesis, distal limb atrophy, dysarthria, and dysphagia. A clinical diagnosis of amyotrophic lateral sclerosis (ALS) was considered before neurophysiological investigation, which disclosed a polyneuropathy and a prolonged central conduction time. One year later, the patient developed dysautonomic symptoms. Following confirmation of adrenal insufficiency, a diagnosis of Allgrove syndrome was made. This is a rare case, and we emphasize its clinical similarity with ALS.
Bentes
C
C
Department of Neurology, EMG Laboratory, Hospital de Santa Maria, Av. Prof. Egas Moniz, 1600, Lisboa, Portugal.
Santos-Bento
M
M
de Sá
J
J
de Lurdes Sales Luís
M
M
de Carvalho
M
M
D000328:Adult; D004574:Electromagnetic Fields; D004576:Electromyography; D004931:Esophageal Achalasia / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D005071:Evoked Potentials / Q000502:physiology; D005938:Glucocorticoids / Q000172:deficiency*; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D009431:Neural Conduction / Q000502:physiology; D013577:Syndrome
D005938:Glucocorticoids