Components and activity of polysaccharides from coarse tea.
Coarse tea contained a high content of polysaccharide complex. Composed of polysaccharide and protein, the polysaccharide complex from tea (TPS) belonged to glycoprotein with the molecular weight () of (10.7-11.0) x 10(4). When mice (7 weeks old, C57BL/8) were injected with TPS, the levels of blood glucose (BG) in normal mice and model mice with high BG were decreased significantly by averages of 13.54 and 22.18%, respectively. The antibody concentration (OD(413 nm)) in the mice injected with 2.4 mg/mL TPS was increased evidently by 44.93% (p < 0.01). TPS treatment was beneficial not only for the subsequent production of interleukin (IL) 2 in spleen cells of adjuvant arthritis (AA) rats but also because it prohibited the body from producing too much IL-1 in AA rats. Treatment of diabetes with coarse tea in both China and Japan may be related to TPS and the content of TPS in coarse tea.
Wang Dongfeng
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Key Laboratory of Tea Biotechnology, Agricultural Ministry of the People's Republic of China, Hefei 230036, People's Republic of China.
Wang Chenghong
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Li Jun
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Zhao Guiwen
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D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D006023:Glycoproteins / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology; D051379:Mice; D008810:Mice, Inbred C57BL; D008970:Molecular Weight; D011134:Polysaccharides / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013662:Tea / Q000737:chemistry*
D000596:Amino Acids; D001786:Blood Glucose; D006023:Glycoproteins; D011134:Polysaccharides; D013662:Tea