Biocompatibility testing using ATP bioluminescence.
This article reports on the potential use of adenosine triphosphate bioluminescence for fast and highly sensitive biocompatibility screening. Results suggest that this technology can be a useful tool for the rapid determination of proliferative and cytotoxic effects. By adding an additional step to measure adenosine diphosphate, it then becomes possible to determine whether cells die by apoptosis or necrosis.
Crouch
S P
SP
LumiTech Ltd, City Link, Nottingham, UK. s.crouch@lumitech.co.uk
D000255:Adenosine Triphosphate / Q000378:metabolism*; D001672:Biocompatible Materials; D002478:Cells, Cultured; D006801:Humans; D008163:Luminescent Measurements; D008422:Materials Testing / Q000379:methods*; D018675:Toxicity Tests
D001672:Biocompatible Materials; D000255:Adenosine Triphosphate