[Detection of telomerase activity and its clinical significance in colonic cancers by PCR-ELISA].
Using the recently developed telomerase PCR-ELISA detection kit, the authors detected the telomerase activity in 12 paired colonic cancer biopsies. It was found that strong telomerase activity was detected in all of the 12 colonic cancer tissues but not in adjacent non-cancerous tissues. These results suggest that the detection of telomerase activity by the PCR-ELISA assay could be used as a supplementary means for the diagnosis of colonic cancer.
Deng
X
X
Cancer Research Institute, Hunan Medical University, Changsha 410078.
Cao
L
L
Weng
X
X
Yao
K
K
D001706:Biopsy; D003110:Colonic Neoplasms / Q000201:enzymology*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D016133:Polymerase Chain Reaction / Q000379:methods; D019098:Telomerase / Q000378:metabolism*
D019098:Telomerase