title: Esophageal pressure and apnea hypopnea index in sleep-disordered breathing.
abstract: Severity of negative esophageal pressure (Pes) and apnea hypopnea index (AHI) were investigated in six cases of upper airway resistance syndrome (UARS) and 11 cases of obstructive sleep apnea syndrome (OSAS). The severity of negative Pes was represented by the highest peak (Pes Max) and the number of increased episodes (more than 13.5 cmH2O) per h (NPesI13.5). There was no significant correlation between Pes indices and AHI. Pes Max and NPesI13.5 were not different among severe OSAS (AHI > 30), mild OSAS (AHI < 30) and UARS. Apnea hypopnea index failed to represent the severity of negative Pes, which is an important aspect of the pathophysiology of sleep-disordered breathing.
authors.affiliation: Department of Medical Science 111, School of Health and Sport Sciences, Osaka University, Japan. watanabe@psy.med.osaka-u.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Watanabe
authors.forename: A
authors.initials: A
authors.lastname: Mikami
authors.forename: Y
authors.initials: Y
authors.lastname: Shigedo
authors.forename: M
authors.initials: M
authors.lastname: Motonishi
authors.forename: H
authors.initials: H
authors.lastname: Honda
authors.forename: K
authors.initials: K
authors.lastname: Kyotani
authors.forename: S
authors.initials: S
authors.lastname: Uruha
authors.forename: K
authors.initials: K
authors.lastname: Terashima
authors.forename: Y
authors.initials: Y
authors.lastname: Teshima
authors.forename: Y
authors.initials: Y
authors.lastname: Sugita
authors.forename: M
authors.initials: M
authors.lastname: Takeda
mesh_terms: D000328:Adult; D000403:Airway Resistance / Q000502:physiology*; D001143:Arousal / Q000502:physiology; D004947:Esophagus / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006874:Hydrostatic Pressure; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000503:physiopathology*