title: Haploinsufficiency for tumor suppression: the hazards of being single and living a long time.
authors.affiliation: Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA. larga002@tc.umn.edu
authors.forename: D A
authors.initials: DA
authors.lastname: Largaespada
mesh_terms: D017209:Apoptosis / Q000235:genetics; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D018628:Gene Dosage; D016147:Genes, Tumor Suppressor; D015473:Leukemia, Promyelocytic, Acute / Q000209:etiology* / Q000235:genetics; D009363:Neoplasm Proteins / Q000378:metabolism*; D015514:Oncogene Proteins, Fusion / Q000378:metabolism*; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000235:genetics / Q000378:metabolism*; D019076:Transgenes
chemical_list: D009363:Neoplasm Proteins; D015514:Oncogene Proteins, Fusion; D019253:Proto-Oncogene Proteins c-bcl-2; C093476:promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein