[The role of L-3-I-123-iodine-alpha-methyltyrosine SPECT in cerebral gliomas].
L-3-I-123-iodine-alpha-methyltyrosine (IMT) is a I-123-labelled amino acid which has been used for single photon emission computed tomography (SPECT) of cerebral gliomas for more than a decade. IMT-SPECT is able to detect tumor infiltration independent of disruptions of the blood-brain barrier which is often difficult with computed tomography or magnetic resonance tomography. The method is useful to detect tumor recurrences and helps to distinguish gliomas from non-neoplastic brain masses. IMT-SPECT is thus a valuable tool in the diagnostic evaluation and in therapy planning of patients with cerebral gliomas.
Weckesser
M
M
Klinik und Poliklinik für Nuklearmedizin, Universität Münster.
Schmidt
D
D
Matheja
P
P
Coenen
H H
HH
Langen
K J
KJ
D001812:Blood-Brain Barrier; D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D005910:Glioma / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes; D008781:Methyltyrosines; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging; D019275:Radiopharmaceuticals; D015899:Tomography, Emission-Computed, Single-Photon
D007457:Iodine Radioisotopes; D008781:Methyltyrosines; D019275:Radiopharmaceuticals; C030855:3-iodo-alpha-methyltyrosine