title: Research and development in biosensors.
abstract: Progress in biosensors has mainly been made by the improvement of the biological components and the implementation of microsystem technologies. Enzymes are still the most appropriate recognition elements because they combine high chemical specificity and inherent biocatalytic signal amplification. A breakthrough has been achieved in the application of membrane-integrated receptor systems for analyte recognition and signal transduction in biosensors. Sensor integration of RNA aptamers has been initiated, and the performance of fully synthetic molecularly imprinted polymers has been improved.
authors.affiliation: University of Potsdam, Institute of Biochemistry and Biology, Karl-Liebknecht-Strasse 24-25, 14476 Golm, Germany. fschell@rz.uni-potsdam.de
authors.forename: F W
authors.initials: FW
authors.lastname: Scheller
authors.forename: U
authors.initials: U
authors.lastname: Wollenberger
authors.forename: A
authors.initials: A
authors.lastname: Warsinke
authors.forename: F
authors.initials: F
authors.lastname: Lisdat
mesh_terms: D000906:Antibodies; D015374:Biosensing Techniques / Q000379:methods*; D018716:Molecular Mimicry; D009696:Nucleic Acids; D014159:Transducers
chemical_list: D000906:Antibodies; D009696:Nucleic Acids