Drugs. Reinventing an ancient cure for malaria.
As drug resistance renders cheap antimalarials ineffective, a promising candidate has emerged from an overlooked source: Asia. Used as herbal remedies in China for 2000 years, artemisinins haven't yet been approved for clinical use in Western countries. But abundant clinical data show that a water-soluble form called artesunate knocks down the number of parasites in the blood faster than any other drug does.
Marshall
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D000818:Animals; D000962:Antimalarials / Q000008:administration & dosage / Q000627:therapeutic use* / Q000633:toxicity; D019306:Artemisia; D037621:Artemisinins; D000077332:Artesunate; D002681:China; D002986:Clinical Trials as Topic; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy*; D010946:Plants, Medicinal; D010963:Plasmodium falciparum / Q000187:drug effects; D012717:Sesquiterpenes / Q000008:administration & dosage / Q000627:therapeutic use* / Q000633:toxicity; D014481:United States; D014486:United States Food and Drug Administration; D014944:World Health Organization
D000962:Antimalarials; D037621:Artemisinins; D004365:Drugs, Chinese Herbal; D012717:Sesquiterpenes; D000077332:Artesunate