title: SUB1, an Arabidopsis Ca2+-binding protein involved in cryptochrome and phytochrome coaction.
abstract: Cryptochromes and phytochromes are the major photosensory receptors in plants and often regulate similar photomorphogenic responses. The molecular mechanisms underlying functional interactions of cryptochromes and phytochromes remain largely unclear. We have identified an Arabidopsis photomorphogenic mutant, sub1, which exhibits hypersensitive responses to blue light and far-red light. Genetic analyses indicate that SUB1 functions as a component of a cryptochrome signaling pathway and as a modulator of a phytochrome signaling pathway. The SUB1 gene encodes a Ca2+-binding protein that suppresses light-dependent accumulation of the transcription factor HY5.
authors.affiliation: Department of Molecular, Cell, and Developmental Biology, University of   California, Los Angeles, CA 90095, USA.
authors.forename: H
authors.initials: H
authors.lastname: Guo
authors.forename: T
authors.initials: T
authors.lastname: Mockler
authors.forename: H
authors.initials: H
authors.lastname: Duong
authors.forename: C
authors.initials: C
authors.lastname: Lin
mesh_terms: D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D029681:Arabidopsis Proteins; D050976:Basic-Leucine Zipper Transcription Factors; D002135:Calcium-Binding Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D056931:Cryptochromes; D003624:Darkness; D029721:Drosophila Proteins; D004843:Epistasis, Genetic; D005136:Eye Proteins; D005420:Flavoproteins / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant; D017343:Genes, Plant; D008027:Light; D008969:Molecular Sequence Data; D009154:Mutation; D009687:Nuclear Proteins / Q000378:metabolism; D010641:Phenotype; D017956:Photoreceptor Cells, Invertebrate; D010834:Phytochrome / Q000378:metabolism*; D051942:Phytochrome A; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D043562:Receptors, G-Protein-Coupled; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D016415:Sequence Alignment; D015398:Signal Transduction
chemical_list: D029681:Arabidopsis Proteins; D050976:Basic-Leucine Zipper Transcription Factors; C538962:CRY1 protein, Arabidopsis; D002135:Calcium-Binding Proteins; D056931:Cryptochromes; D029721:Drosophila Proteins; D005136:Eye Proteins; D005420:Flavoproteins; C109254:HY5 protein, Arabidopsis; D009687:Nuclear Proteins; C497973:PHYA protein, Arabidopsis; D051942:Phytochrome A; D010940:Plant Proteins; D043562:Receptors, G-Protein-Coupled; D011993:Recombinant Fusion Proteins; C421103:SUB1 protein, Arabidopsis; C119828:cry protein, Drosophila; D010834:Phytochrome