Cadherins as modulators of angiogenesis and the structural integrity of blood vessels.
The endothelial cell adhesion molecules, neural- and vascular endothelial-cadherin play essential roles in the formation of stable and fully functional blood vessels. This commentary discusses the multiple functions of these two cadherins in angiogenesis and the maintenance of blood vessel structural integrity.
Blaschuk
O W
OW
Department of Surgery, McGill University, Montreal, Quebec, Canada.
Rowlands
T M
TM
D000818:Animals; D001808:Blood Vessels / Q000033:anatomy & histology / Q000502:physiology*; D015820:Cadherins / Q000502:physiology*; D002448:Cell Adhesion / Q000502:physiology; D004730:Endothelium, Vascular / Q000502:physiology*; D006706:Homeostasis; D006801:Humans; D018919:Neovascularization, Physiologic / Q000502:physiology*
D015820:Cadherins