Safety and effectiveness of Niaspan when added sequentially to a statin for treatment of dyslipidemia.
Niaspan, when added to a stable dose of a statin in 66 subjects, was found to be safe and highly effective in improving lipid parameters. Subgroup analyses demonstrated its effectiveness in lowering low-density lipoprotein cholesterol in persons not at the National Cholesterol and Education Program low-density lipoprotein cholesterol target and in raising high-density lipoprotein cholesterol in persons with levels < 40 mg/dl.
Wolfe
M L
ML
Department of Medicine, University of Pennsylvania Health System, Philadelphia, USA.
Vartanian
S F
SF
Ross
J L
JL
Bansavich
L L
LL
Mohler
E R
ER
Meagher
E
E
Friedrich
C A
CA
Rader
D J
DJ
D000328:Adult; D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009525:Niacin / Q000627:therapeutic use*; D012189:Retrospective Studies; D016896:Treatment Outcome
D000924:Anticholesteremic Agents; D009525:Niacin