Pulmonary hyalinising granuloma: a case report and literature review.
This is a case of a rare lung disease known as pulmonary hyalinising granuloma, which is usually discovered incidentally on chest radiographs and poses diagnostic difficulties but has an excellent prognosis. In this case a 75-year-old man had a 6-year history of undiagnosed, enlarging, bilateral dense apical infiltrates. The patient died from his tobacco smoke-related emphysema, which led to diagnosis of the lesion. At autopsy both lungs showed well-defined apical, hard, grey-white masses covered by a rind of thickened adherent pleura. Histologically, the lesion was composed of dense, haphazard lamellar, keloid-like collagen concentrically arranged around blood vessels with extension into the pleura and perivascular collections of lymphocytes and plasma cells.
Russell
A F
AF
Department of Anatomical Pathology Central Coast Area Health Service, Gosford NSW, Australia.
Suggit
R I
RI
Kazzi
J C
JC
D000368:Aged; D017809:Fatal Outcome; D015769:Granuloma, Respiratory Tract / Q000473:pathology*; D006801:Humans; D006818:Hyalin; D008171:Lung Diseases / Q000473:pathology*; D008297:Male