The trehalose operon of Pseudomonas fluorescens ATCC 17400.
The trehalose operon of Pseudomonas fluorescens ATCC 17400 consists of treP, treA and treR. The gene treP codes for a putative enzyme II subunit of the phosphotransferase system that catalyzes the phosphorylation of trehalose together with its translocation across the cell membrane and treA encodes a putative phosphotrehalase, which hydrolyzes the incoming trehalose-6-phosphate into glucose and glucose-6-phosphate. Both genes are negatively regulated by TreR, a repressor of the FadR-GntR family of transcription regulators. The operon that is induced by trehalose present in the medium shows a high similarity both in the function of genes and in the regulation with the trehalose operon of Bacillus subtilis.
Matthijs
S
S
Laboratorium Microbiële Interacties, Vrije Universiteit Brussel, Sint-Genesius-Rode, Belgium.
Koedam
N
N
Cornelis
P
P
De Greve
H
H
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics; D001483:Base Sequence; D003001:Cloning, Molecular; D004186:Disaccharidases / Q000235:genetics / Q000378:metabolism; D005798:Genes, Bacterial; D005809:Genes, Regulator; D008969:Molecular Sequence Data; D009154:Mutation; D009876:Operon; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System / Q000235:genetics; D011551:Pseudomonas fluorescens / Q000201:enzymology / Q000235:genetics*; D016415:Sequence Alignment; D014157:Transcription Factors / Q000235:genetics; D014199:Trehalose / Q000235:genetics*; D001616:beta-Galactosidase / Q000032:analysis / Q000378:metabolism
D001426:Bacterial Proteins; C080512:TraR protein, Agrobacterium tumefaciens; D014157:Transcription Factors; D014199:Trehalose; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System; C094583:phosphoenolpyruvate-trehalose phosphotransferase, bacteria; D004186:Disaccharidases; D001616:beta-Galactosidase; C040631:alpha, alpha-phosphotrehalase