title: Treatment of perforating collagenosis of diabetes and renal failure with allopurinol.
abstract: We present a case of widespread reactive perforating collagenosis in a 63-year-old woman undergoing haemodialysis after diabetic nephropathy, who was treated successfully with allopurinol. The patient responded well and rapidly to a dose of 100 mg allopurinol daily. It is suggested that more patients with reactive perforating collagenosis may benefit from allopurinol therapy.
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Roskilde Hospital, DK-4000 Roskilde, Denmark. munch@ddlnet.dk
authors.forename: M
authors.initials: M
authors.lastname: Munch
authors.forename: E
authors.initials: E
authors.lastname: Balslev
authors.forename: G B
authors.initials: GB
authors.lastname: Jemec
mesh_terms: D000493:Allopurinol / Q000627:therapeutic use*; D003095:Collagen Diseases / Q000188:drug therapy*; D003928:Diabetic Nephropathies / Q000150:complications*; D005260:Female; D016166:Free Radical Scavengers / Q000627:therapeutic use*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects
chemical_list: D016166:Free Radical Scavengers; D000493:Allopurinol