Comparison of effects of clopidogrel versus ticlopidine on platelet function in patients undergoing coronary stent placement.
Clopidogrel in combination with aspirin administered as a loading dose of 450 mg reveals an accelerated antiplatelet effect in the early hours after first administration in patients undergoing coronary stent placement.
Gawaz
M
M
Medizinische Klinik, Klinikum rechts der Isar und Deutsches Herzzentrum, Technische Universität München, Germany. gawaz@dhm.mhn.de
Seyfarth
M
M
Müller
I
I
Rüdiger
S
S
Pogatsa-Murray
G
G
Wolf
B
B
Schömig
A
A
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D000077144:Clopidogrel; D003327:Coronary Disease / Q000097:blood / Q000628:therapy*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage* / Q000009:adverse effects; D010979:Platelet Function Tests; D011446:Prospective Studies; D012008:Recurrence; D015607:Stents; D013988:Ticlopidine / Q000008:administration & dosage* / Q000009:adverse effects / Q000031:analogs & derivatives*
D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine