title: Case study. Risperidone-Induced neuroleptic malignant syndrome in an adolescent.
abstract: Neuroleptic malignant syndrome (NMS) is a potentially fatal complication of neuroleptic therapy, characterized by fever, rigidity, mental status changes, and autonomic instability. Although NMS was previously associated with the use of high-potency neuroleptics, cases have begun to emerge with atypical neuroleptics. This article presents a risperidone-induced case in the youngest patient to date, raising issues concerning our perceptions, the safety of newer neuroleptics, and treatment of NMS.
authors.affiliation: Department of Psychiatry and Behavioral Science, The Children's National Medical Center, Washington, DC 20010, USA. arobb@cnmc.org
authors.forename: A S
authors.initials: AS
authors.lastname: Robb
authors.forename: W
authors.initials: W
authors.lastname: Chang
authors.forename: H K
authors.initials: HK
authors.lastname: Lee
authors.forename: M S
authors.initials: MS
authors.lastname: Cook
mesh_terms: D000293:Adolescent; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy; D005260:Female; D006801:Humans; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis* / Q000628:therapy; D018967:Risperidone / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D014150:Antipsychotic Agents; D018967:Risperidone