title: Activation of the dienophilicity of indoles in normal electron demand [4 + 2] cycloadditions under high pressure.
abstract: [reaction: see Text] Activation by either high pressure or a combination of Lewis acid catalysis and high pressure allows indole derivatives to behave as dienophiles in [4 + 2] cycloaddition reactions under mild conditions. The biactivation mode has the highest impact on the stereoselectivity of the reaction. The cycloadducts resulting from these reactions are characterized by boat-shape conformations that bear well-defined orthogonal planes.
authors.affiliation: Laboratoire des Fonctions Azotées et Oxygénées Complexes, UMR 6014 CNRS, Université de Rouen-IRCOF, Rue Tesnière, F-76821 Mont Saint Aignan, France.
authors.forename: I
authors.initials: I
authors.lastname: Chataigner
authors.forename: E
authors.initials: E
authors.lastname: Hess
authors.forename: L
authors.initials: L
authors.lastname: Toupet
authors.forename: S R
authors.initials: SR
authors.lastname: Piettre