New acetogenin peroxides from the Indian sponge Acarnus bicladotylota.
Two new cyclic peroxides (1 and 2) and the known metabolite 3 have been found in the organic extract of the Indian sponge Acarnus bicladotylota. The structure of the new products has been assured by chemical and spectroscopic methods. The absolute stereochemistry of 1-3 has been determined by Mosher's method on the semisynthetic derivative 4.
Fontana
A
A
Istituto per la Chimica di Molecole di Interesse Biologico (ICMIB) del CNR, Via Toiano 6, 80072 Arco Felice (Na), Italy. afontana@icmib.na.cnr.it
d'Ippolito
G
G
D'Souza
L
L
Mollo
E
E
Parameswaram
P S
PS
Cimino
G
G
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000302:isolation & purification; D005663:Furans / Q000737:chemistry*; D007194:India; D007783:Lactones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010545:Peroxides / Q000737:chemistry* / Q000302:isolation & purification; D011161:Porifera / Q000737:chemistry*; D013055:Spectrophotometry, Infrared
D000970:Antineoplastic Agents; D005663:Furans; D007783:Lactones; D010545:Peroxides; C112079:isomurisolenin