title: Sepsis as an unusual event in dyskeratosis follicularis.
abstract: Dyskeratosis follicularis is a genetic disorder characterized by pathogenetic changes of keratinization. We report on a severe case of the disease with an unusual manifestation involving Staphylococcal sepsis. The patient was treated systemically with infusions, oral antibiotics, and retinoids. Antiseptics, keratolytic ointments, and creams were given topically to promote epithelization. His condition improved dramatically after 14 days of treatment. All erosions of the trunk, extremities, neck, and head had epithelized. We suspect that extreme sun exposure and neglect of care on genetically susceptible sites triggered the sepsis.
authors.affiliation: Department of Dermatovenerology, Zagreb University Hospital Center, Salata 4, 10000 Zagreb, Croatia. nina@mef.hr
authors.forename: V
authors.initials: V
authors.lastname: Milavec-Puretić
authors.forename: J
authors.initials: J
authors.lastname: Lipozencić
authors.forename: N
authors.initials: N
authors.lastname: Sustić
authors.forename: N
authors.initials: N
authors.lastname: Pećina-Slaus
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents; D016470:Bacteremia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D007644:Darier Disease / Q000150:complications* / Q000175:diagnosis; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index; D013207:Staphylococcal Skin Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013211:Staphylococcus aureus; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents