title: Neuroscience. An antibiotic to treat Alzheimer's?
abstract: An antibiotic once used to treat traveler's diarrhea might battle Alzheimer's disease as well, researchers announced here last week at the Society for Neuroscience's annual meeting. The drug dissolves Alzheimer's-like plaques in mouse brains, apparently by trapping the copper and zinc that stud these deposits. A clinical trial to test whether the drug helps people with Alzheimer's is already under way.
authors.forename: L
authors.initials: L
authors.lastname: Helmuth
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D017322:Clinical Trials, Phase II as Topic; D007464:Clioquinol / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D003300:Copper / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D051379:Mice; D058225:Plaque, Amyloid / Q000187:drug effects* / Q000378:metabolism; D015032:Zinc / Q000378:metabolism / Q000494:pharmacology
chemical_list: D016229:Amyloid beta-Peptides; D003300:Copper; D007464:Clioquinol; D015032:Zinc