Novel approach to bleeding in patients undergoing cardiac surgery with liver dysfunction.
We describe two patients with significant liver dysfunction (Child--Pugh class B) who underwent cardiac surgery at our institution facilitated by the use of a prothrombin complex concentrate for the management of postoperative bleeding.
Stuklis
R G
RG
Department of Cardiothoracic Surgery and Haematology, Southampton General Hospital, Southampton, UK. rstuklis@yahoo.com
O'Shaughnessy
D F
DF
Ohri
S K
SK
D000328:Adult; D001779:Blood Coagulation Factors / Q000627:therapeutic use*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D006331:Heart Diseases / Q000150:complications / Q000601:surgery; D006488:Hemostasis, Surgical; D006801:Humans; D008108:Liver Diseases, Alcoholic / Q000150:complications; D008297:Male; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000188:drug therapy*
D001779:Blood Coagulation Factors; C025667:prothrombin complex concentrates