3-oxo-rhazinilam: a new indole alkaloid from Rauvolfia serpentina x Rhazya stricta hybrid plant cell cultures.
A new monoterpenoid indole alkaloid, 3-oxo-rhazinilam (1), was isolated from intergeneric somatic hybrid cell cultures of Rauvolfia serpentina and Rhazya stricta, and the structure was determined by detailed 1D and 2D NMR analysis. It was also proved that 3-oxo-rhazinilam (1) is a natural constituent of the hybrid cells.
Gerasimenko
I
I
Department of Pharmaceutical Biology, Institute of Pharmacy, Johannes Gutenberg-University, Staudinger Weg 5, D-55099 Mainz, Germany.
Sheludko
Y
Y
Stöckigt
J
J
D000470:Alkaloids / Q000737:chemistry* / Q000378:metabolism; D002478:Cells, Cultured; D018920:Coculture Techniques; D007212:Indolizines; D007769:Lactams; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010946:Plants, Medicinal / Q000737:chemistry*; D011926:Rauwolfia / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
C428189:3-oxo-rhazinilam; D000470:Alkaloids; D007212:Indolizines; D007769:Lactams