Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases.
Sherman
M Y
MY
Boston Biomedical Research Institute, 64 Grove Street, Watertown, MA 02472, USA. sherman@alpha.bbri.org
Goldberg
A L
AL
D000375:Aging / Q000378:metabolism; D017209:Apoptosis; D020022:Genetic Predisposition to Disease; D006360:Heat-Shock Proteins / Q000378:metabolism; D006868:Hydrolysis; D002479:Inclusion Bodies / Q000378:metabolism; D018832:Molecular Chaperones / Q000378:metabolism / Q000494:pharmacology; D019636:Neurodegenerative Diseases / Q000209:etiology* / Q000235:genetics / Q000378:metabolism*; D018696:Neuroprotective Agents / Q000378:metabolism / Q000494:pharmacology; D011487:Protein Conformation; D011489:Protein Denaturation; D017510:Protein Folding; D011499:Protein Processing, Post-Translational; D019680:Trinucleotide Repeat Expansion / Q000235:genetics; D014452:Ubiquitins / Q000378:metabolism
D006360:Heat-Shock Proteins; D018832:Molecular Chaperones; D018696:Neuroprotective Agents; D014452:Ubiquitins