Brain calculus: neural integration and persistent activity.
Tank and colleagues make in vivo cellular recordings from neurons in a "neural integrator" of the goldfish involved in maintaining eye position. In this circuit, "working" memory may be the result of persistent changes in the state of the local network.
McCormick
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Section of Neurobiology, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06510, USA. david.mccormick@yale.edu
D000818:Animals; D001921:Brain / Q000502:physiology*; D005403:Fixation, Ocular / Q000502:physiology; D006054:Goldfish; D006801:Humans; D008568:Memory / Q000502:physiology; D009415:Nerve Net / Q000502:physiology; D009474:Neurons / Q000502:physiology*