title: The impact of semantic impairment on word stem completion in Alzheimer's disease.
abstract: Both the extent of semantic memory impairment and the level of processing attained during encoding might constitute critical factors in determining the amount of word-stem completion (WSC) priming encountered in Alzheimer's disease (AD) subjects. We investigated the impact of varying encoding level in AD and elderly normal subjects, using a set of stimuli ranked as "intact" or "degraded" in terms of each subject's semantic knowledge on probe questions. For both shallow and deep encoding conditions, overall priming in the two subject groups was equivalent. However, for the deep encoding condition, consisting of a semantic judgment task performed on each target word, the priming effect noted in AD subjects was significantly smaller for semantically degraded items than for semantically intact items. Results indicate that the degree of semantic impairment represents one important variable affecting the amount of WSC priming which results when deep encoding procedures are used at study.
authors.affiliation: Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Québec, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Beauregard
authors.forename: H
authors.initials: H
authors.lastname: Chertkow
authors.forename: D
authors.initials: D
authors.lastname: Gold
authors.forename: S
authors.initials: S
authors.lastname: Bergman
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000150:complications / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000209:etiology*; D008606:Mental Processes; D012660:Semantics