PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases.
A new protein domain was found in several proteins involved in apoptosis, inflammation, cancer and immune responses. Its location within these proteins and predicted fold suggests that it functions as a protein-protein interaction domain, possibly uniting different signaling pathways.
Pawłowski
K
K
Program in Bioinformatics and Biological Complexity, The Burnham Institute, 10901 N. Torrey Pines Road, La Jolla, CA 92037, USA.
Pio
F
F
Chu
Z
Z
Reed
J C
JC
Godzik
A
A
D000595:Amino Acid Sequence; D000818:Animals; D017209:Apoptosis; D001327:Autoimmune Diseases / Q000378:metabolism*; D003598:Cytoskeletal Proteins; D016208:Databases, Factual; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D008969:Molecular Sequence Data; D009369:Neoplasms / Q000378:metabolism*; D011485:Protein Binding; D017510:Protein Folding; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry; D000071198:Pyrin; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction
D003598:Cytoskeletal Proteins; D011506:Proteins; D000071198:Pyrin