[Pharmacological prophylaxis of vestibulo-autonomous syndrome (motion sickness) in model investigations].
The authors summarize results of multiyear investigations at the Institute of Biomedical Problems of induced motion sickness and development of prophylactic medicaments representing various classes of biologically active substances (choline blocking agents, sympathomimetics, antihistamines etc.) prescribed singularly or in an combination based on the knowledge of MS-provoking inter-receptor interactions and therapeutic effects of drugs.
Shashkov
V S
VS
Iasnetsov
V V
VV
Shashkov
A V
AV
Il'ina
S L
SL
Galle
R R
RR
Sabaev
V V
VV
Potapov
M G
MG
D000328:Adult; D001341:Autonomic Nervous System / Q000187:drug effects / Q000503:physiopathology; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D018680:Cholinergic Antagonists / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D006634:Histamine H1 Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009760:Nystagmus, Physiologic / Q000187:drug effects / Q000502:physiology; D018489:Space Motion Sickness / Q000503:physiopathology / Q000517:prevention & control*; D018561:Space Simulation / Q000379:methods*; D013566:Sympathomimetics / Q000627:therapeutic use*; D013577:Syndrome; D014722:Vestibule, Labyrinth / Q000187:drug effects / Q000503:physiopathology
D018680:Cholinergic Antagonists; D006634:Histamine H1 Antagonists; D013566:Sympathomimetics