Antibody libraries in drug and target discovery.
Antibody libraries have come of age in the generation and evolution of monoclonal antibodies for therapeutic applications. Here, with an emphasis on cancer therapy, several examples are presented that illustrate the ability to design, engineer and select antibody libraries for different rationales in drug and target discovery.
Rader
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Department of Molecular Biology, BCC-526 The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, CA, USA