The function and regulation of vasa-like genes in germ-cell development.
The vasa gene, essential for germ-cell development, was originally identified in Drosophila, and has since been found in other invertebrates and vertebrates. Analysis of these vasa homologs has revealed a highly conserved role for Vasa protein among different organisms, as well as some important differences in its regulation.
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Department for Developmental Biology, Institute for Biology I, Freiburg University, 79104 Freiburg, Germany. razerez@sun2.ruf.uni-freiburg.de
D000818:Animals; D053487:DEAD-box RNA Helicases; D015971:Gene Expression Regulation, Enzymologic; D005854:Germ Cells / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D007448:Invertebrates / Q000196:embryology / Q000235:genetics; D021381:Protein Transport; D020365:RNA Helicases / Q000235:genetics* / Q000378:metabolism*; D017385:Sequence Homology; D014714:Vertebrates / Q000196:embryology / Q000235:genetics
C498288:DDX4 protein, human; D053487:DEAD-box RNA Helicases; D020365:RNA Helicases