Inhibition of matrix metalloproteinases by bisphosphonates may in part explain their effects in the treatment of multiple myeloma.
Teronen
O
O
Laitinen
M
M
Salo
T
T
Hanemaaijer
R
R
Heikkilä
P
P
Konttinen
Y T
YT
Sorsa
T
T
D000970:Antineoplastic Agents / Q000494:pharmacology; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology; D004164:Diphosphonates / Q000494:pharmacology* / Q000627:therapeutic use; D015536:Down-Regulation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D061965:Matrix Metalloproteinase Inhibitors; D009101:Multiple Myeloma / Q000188:drug therapy* / Q000201:enzymology; D009362:Neoplasm Metastasis / Q000188:drug therapy / Q000517:prevention & control
D000970:Antineoplastic Agents; D004164:Diphosphonates; D004791:Enzyme Inhibitors; D061965:Matrix Metalloproteinase Inhibitors