title: Diagnostic accuracy of intraoperative imprint cytology in ovarian epithelial tumors.
abstract: OBJECTIVE
  To evaluate imprint cytology (IC) as the intraoperative pathological consultations for ovarian epithelial tumors (OET).
  
  
  METHODS
  We reviewed ICs obtained from 354 consecutive surgical specimens of OET. Cytological specimens were classified into five categories. Final pathological diagnoses were made according to the WHO classification. We performed logistic regression analysis, calculated the limits among benign, borderline, and malignant lesions, and analyzed the diagnostic accuracy. We also made receiver operating characteristic (ROC) curves regarding IC.
  
  
  RESULTS
  The accuracies to differentiate benign and malignant lesions were 87.1 and 83.6%, respectively. In contrast, that of borderline lesions was 30.0%. The areas under ROC curves to diagnose benign, and malignant lesions were 0.888 (P<0.05) and 0.951 (P<0.05), respectively, that meant IC was significantly useful for diagnosis of malignancy.
  
  
  CONCLUSIONS
  IC applied to OET was proved to be practically useful in establishing an intraoperative diagnosis by ROC curves.
authors.affiliation: Second Department of Pathology, Chiba University, Chiba, Japan. ynagai@med.m.chica-u.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Nagai
authors.forename: N
authors.initials: N
authors.lastname: Tanaka
authors.forename: F
authors.initials: F
authors.lastname: Horiuchi
authors.forename: S
authors.initials: S
authors.lastname: Ohki
authors.forename: K
authors.initials: K
authors.lastname: Seki
authors.forename: S
authors.initials: S
authors.lastname: Sekiya
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D002277:Carcinoma / Q000473:pathology* / Q000601:surgery; D046508:Culture Techniques; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016015:Logistic Models; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods*; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D012372:ROC Curve; D012189:Retrospective Studies; D012680:Sensitivity and Specificity