Current status of prophylactic surgery for hereditary breast and gynecologic cancers.
Given the limitations regarding the impact of screening and the uncertainties concerning chemoprevention for women with significant genetic susceptibilities to breast, endometrial and ovarian cancers, recent research and publications on prophylactic surgery for cancer prevention and improved long-term survival for women at hereditary risk have increasing importance.
Lynch
H T
HT
Department of Preventive Medicine, Creighton University School of Medicine, Omaha, Nebraska 68178, USA. htlynch@creighton.edu
Casey
M J
MJ
D001943:Breast Neoplasms / Q000235:genetics / Q000517:prevention & control* / Q000601:surgery*; D005260:Female; D020022:Genetic Predisposition to Disease; D005833:Genital Neoplasms, Female / Q000235:genetics / Q000517:prevention & control* / Q000601:surgery*; D006801:Humans