title: [Magnetic resonance imaging diagnosis of craniobasal cerebrospinal fluid fistulas by 3D-CISS sequence].
abstract: Recently, a Magnetic Resonance Imaging (MRI)-technique has been developed to diagnose the exact anatomical location of fistulas of the cerebrospinal fluid (CSF). This method is called 3D-constructive interference steady state-sequence (CISS) but it is not well known in clinical practice. Aim of the study was the evaluation of specificity and sensitivity of CISS-MRI. 12 patients with rhinoliquorrhea after head injury (n = 7) or skull base tumours (n = 5) were examined by CISS-MRI. The examinations were performed with a 1.5 T whole body MRI scanner in prone position and coronal plane sections. In cases of CSF leckage the sensitivity for detection of a CSF fistula was 100%. In comparison with intraoperative findings, specificity was 100%: in all cases, a dural lesion in anatomical correlation to MRI was detected. Further advantages of this method are its non-invasive character, no need for contrast application, no radiation exposure, and exact localisation of additional anatomical findings (brain herniation, brain contusions).
authors.affiliation: Klinik für Neurochirurgie, Otto-von-Guericke-Universität, Magdeburg.
authors.forename: S
authors.initials: S
authors.lastname: Klein
authors.forename: D
authors.initials: D
authors.lastname: Woischneck
authors.forename: R
authors.initials: R
authors.lastname: Firsching
authors.forename: T
authors.initials: T
authors.lastname: Heinrichs
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002555:Cerebrospinal Fluid / Q000378:metabolism*; D006259:Craniocerebral Trauma / Q000150:complications*; D005260:Female; D005402:Fistula / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D016684:Prone Position; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D019292:Skull Base Neoplasms / Q000150:complications*; D013118:Spinal Cord Diseases / Q000175:diagnosis* / Q000209:etiology