title: Mechanical valve thrombosis during pregnancy.
abstract: Mechanical valve thrombosis is a life-threatening event, and prevention with meticulous anticoagulation is crucial. Pregnancy is associated with a hypercoagulable state that further emphasizes the importance of adequate anticoagulation. A case of mechanical mitral valve thrombosis in a pregnant woman due to suboptimal anticoagulation is presented. Methods of anticoagulation, as well as thrombolytic and surgical therapies, are discussed.
authors.affiliation: Division of Cardiology, St Paul's Hospital, Vancouver, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Saw
authors.forename: C
authors.initials: C
authors.lastname: Thompson
authors.forename: I
authors.initials: I
authors.lastname: Macdonald
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008943:Mitral Valve; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000628:therapy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis / Q000601:surgery; D017131:Thrombectomy; D013927:Thrombosis / Q000209:etiology* / Q000601:surgery
chemical_list: D000925:Anticoagulants