title: Laryngotracheoplasty for subglottic stenosis in Down Syndrome children: the Cincinnati experience.
abstract: Previous studies from our institution have noted difficulties in the surgical repair of subglottic stenosis (SGS) in children with Down Syndrome. The objectives of this paper were to update our 15 year experience in the Down Syndrome patient population, compare our results with our overall series of laryngotracheoplasty for SGS, and to report on the increased incidence of posterior glottic stenosis (PGS) within this group of patients. Medical records of all children with SGS and Down Syndrome evaluated between 1982 and 1997 were reviewed for history of prior intubation, tracheotomy, gastroesophageal reflux disease (GERD), pre-operative SGS grade, and decannulation. From this review several conclusions have been drawn. First, the risk factors for SGS appear to be the same in the Down Syndrome group as the general population. Second, SGS continues to be more prevalent among children with Down Syndrome than among children in the general population. Third, we have now found a higher rate of PGS within these patients when compared to our overall series. Finally, it now seems that our decannulation rates in Down Syndrome children are approaching our overall series results.
authors.affiliation: Department of Pediatric Otolaryngology, Children's Hospital Medical Center, Burnet Ave., Cincinnati, OH 45229, USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Boseley
authors.forename: D T
authors.initials: DT
authors.lastname: Link
authors.forename: S R
authors.initials: SR
authors.lastname: Shott
authors.forename: C M
authors.initials: CM
authors.lastname: Fitton
authors.forename: C M
authors.initials: CM
authors.lastname: Myer
authors.forename: R T
authors.initials: RT
authors.lastname: Cotton
mesh_terms: D004314:Down Syndrome / Q000150:complications*; D005931:Glottis; D006801:Humans; D007829:Laryngostenosis / Q000150:complications / Q000453:epidemiology / Q000601:surgery*; D007830:Larynx / Q000601:surgery; D009820:Ohio / Q000453:epidemiology; D012189:Retrospective Studies; D014132:Trachea / Q000601:surgery