Animal models to explore mechanisms of tolerance induction to FVIII: SCID mice and SCID-FVIII-KO mice.
Gilles
J G
JG
Center for Molecular and Vascular Biology, Katholieke Universiteit Leuven, Belgium. jeanguy.gilles@med.kuleuven.ac.be
Vanzieleghem
B
B
Saint-Remy
J M
JM
D000818:Animals; D000906:Antibodies / Q000008:administration & dosage / Q000494:pharmacology; D001323:Autoantibodies / Q000097:blood / Q000145:classification / Q000187:drug effects; D023201:CD40 Ligand / Q000276:immunology; D004195:Disease Models, Animal; D005169:Factor VIII / Q000008:administration & dosage / Q000276:immunology*; D006467:Hemophilia A / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D007108:Immune Tolerance / Q000187:drug effects; D017710:Lymphocyte Transfusion; D051379:Mice; D018345:Mice, Knockout; D016513:Mice, SCID; D014183:Transplantation, Heterologous
D000906:Antibodies; D001323:Autoantibodies; D023201:CD40 Ligand; D005169:Factor VIII