title: Quantitative estimation of chromosome aberration frequency in cancer patients induced by endogenous and exogenous factors.
abstract: In patients with skin melanoma and colon cancer, cell distribution by the number of chromosome aberrations cannot be described by Poisson distribution, but corresponds to a bipopulation model combining the Poisson and geometric distributions. In contrast to the control, in patients with malignant tumors, cells with geometric distribution possess the majority of chromosomal aberrations.
authors.affiliation: Medical Genetic Research Center, Russian Academy of Medical Sciences, Moscow, Russia.
authors.forename: A N
authors.initials: AN
authors.lastname: Chebotarev
authors.forename: O P
authors.initials: OP
authors.lastname: Kirichenko
authors.forename: O I
authors.initials: OI
authors.lastname: Sokolova
mesh_terms: D002869:Chromosome Aberrations; D003110:Colonic Neoplasms / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D008545:Melanoma / Q000235:genetics* / Q000378:metabolism; D009153:Mutagens / Q000009:adverse effects; D012878:Skin Neoplasms / Q000235:genetics* / Q000378:metabolism
chemical_list: D009153:Mutagens