Reversible posterior leukoencephalopathy during the treatment of acute lymphoblastic leukemia.
Three children with acute lymphoblastic leukemia developed altered mental status, headaches, seizures, and visual changes associated with reversible posterior cerebral changes on MRI. These clinical and radiologic findings were consistent with the reversible posterior leukoencephalopathy syndrome, which has not been widely recognized in this setting.
Shin
R K
RK
Division of Neuro-ophthalmology Services, Children's Hospital of Philadelphia, PA, USA.
Stern
J W
JW
Janss
A J
AJ
Hunter
J V
JV
Liu
G T
GT
D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000209:etiology* / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*