title: Use of transjugular intrahepatic portosystemic shunt as a bridge to liver transplantation in a patient with severe hepatopulmonary syndrome.
abstract: Hepatopulmonary syndrome (HPS) is defined by the presence of the triad of liver disease, arterial hypoxemia, and intrapulmonary vascular dilatation. The clinical implication of this disorder is impairment of gas exchange. Numerous reports in the literature show that this condition is reversible with orthotopic liver transplantation (OLT). However, patients with HPS often present with PaO(2) levels that are quite low. OLT with a preoperative PaO(2) less than 50 mm Hg is associated with unacceptably high mortality and morbidity. We report a case of severe HPS in which a transjugular intrahepatic portosystemic shunt was successfully used to improve oxygenation, thus allowing a successful elective OLT.
authors.affiliation: Division of Digestive Diseases and Nutrition, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.
authors.forename: H M
authors.initials: HM
authors.lastname: Lasch
authors.forename: M W
authors.initials: MW
authors.lastname: Fried
authors.forename: S L
authors.initials: SL
authors.lastname: Zacks
authors.forename: P
authors.initials: P
authors.lastname: Odell
authors.forename: M W
authors.initials: MW
authors.lastname: Johnson
authors.forename: D A
authors.initials: DA
authors.lastname: Gerber
authors.forename: F S
authors.initials: FS
authors.lastname: Sandhu
authors.forename: J H
authors.initials: JH
authors.lastname: Fair
authors.forename: R
authors.initials: R
authors.lastname: Shrestha
mesh_terms: D005260:Female; D020065:Hepatopulmonary Syndrome / Q000097:blood / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D019168:Portasystemic Shunt, Transjugular Intrahepatic
chemical_list: D010100:Oxygen