title: Postictal stability of proton magnetic resonance spectroscopy imaging (1H-MRSI) ratios in temporal lobe epilepsy.
abstract: Interictal proton (1H) MRS is increasingly used for seizure lateralization in patients with temporal lobe epilepsy (TLE). Studies reporting postictal 1H-MRS metabolite changes in patients with TLE are few and contradictory. The authors prospectively performed interictal and postictal proton magnetic resonance spectroscopy imaging (1H-MRSI) studies in seven patients with TLE. The authors found no consistent changes in metabolite peak area ratios between studies, suggesting that 1H-MRS ratios remain stable between interictal and postictal state in TLE.
authors.affiliation: UAB Epilepsy Center, Department of Neurology, University of Alabama at Birmingham, USA.
authors.forename: B
authors.initials: B
authors.lastname: Maton
authors.forename: A
authors.initials: A
authors.lastname: Londoño
authors.forename: S
authors.initials: S
authors.lastname: Sawrie
authors.forename: R
authors.initials: R
authors.lastname: Knowlton
authors.forename: R
authors.initials: R
authors.lastname: Martin
authors.forename: R
authors.initials: R
authors.lastname: Kuzniecky
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000378:metabolism*; D004833:Epilepsy, Temporal Lobe / Q000378:metabolism* / Q000503:physiopathology; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D011522:Protons
chemical_list: D011522:Protons