title: Combined pars plana lensectomy-vitrectomy with open-loop flexible anterior chamber intraocular lens (AC IOL) implantation for subluxated lenses.
abstract: OBJECTIVE
  To review our experience with combined pars plana lensectomy-vitrectomy and open-loop flexible anterior chamber intraocular lens (AC IOL) implantation for managing subluxated crystalline lenses.
  
  
  METHODS
  Retrospective review of 36 consecutive eyes (28 patients), all of which had subluxated crystalline lenses, managed by pars plana lensectomy-vitrectomy with insertion of an open-loop flexible AC IOL. The study was performed at the Medical College of Wisconsin, Milwaukee, over an 8-year period.
  
  
  RESULTS
  An average preoperative visual acuity of 20/163 (range, 20/25 to hand motions) improved to 20/36 (range, 20/20 to 4/200) with surgery after a mean follow-up of 14 months (range, 1 to 59 months) (P < .001, Student's paired t test). Final visual acuity of 20/40 or better was achieved in 75% of eyes (27/36). Complications included cystoid macular edema (8% [3/36]), pupillary block (6% [2/36]), retinal detachment (3% [1/36]), hyphema (3% [1/36]), wound leak (3% [1/36]), and transient vitreous hemorrhage (3% [1/36]). No persistent ocular hypertension was seen, nor did angle abnormalities or corneal decompensation develop.
  
  
  CONCLUSIONS
  Pars plana lensectomy-vitrectomy with AC IOL implantation appears to be an excellent technique for managing subluxated crystalline lenses. It is associated with a significant improvement in visual acuity (P < .001) and avoids many of the complications seen with extraction of a subluxated lens through a limbal wound. Additionally, use of an AC IOL offers a simplified alternative to placement of a ciliary sulcus sutured posterior chamber intraocular lens (PC IOL).
authors.affiliation: Eye Institute, Medical College of Wisconsin, Milwaukee, USA.
authors.forename: S
authors.initials: S
authors.lastname: Kazemi
authors.forename: W J
authors.initials: WJ
authors.lastname: Wirostko
authors.forename: S
authors.initials: S
authors.lastname: Sinha
authors.forename: W F
authors.initials: WF
authors.lastname: Mieler
authors.forename: S B
authors.initials: SB
authors.lastname: Koenig
authors.forename: B P
authors.initials: BP
authors.lastname: Sheth
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000601:surgery*; D017889:Exfoliation Syndrome / Q000150:complications; D005131:Eye Injuries / Q000150:complications; D005260:Female; D006801:Humans; D007906:Lens Subluxation / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D007908:Lens, Crystalline / Q000601:surgery*; D007910:Lenses, Intraocular; D008297:Male; D008382:Marfan Syndrome / Q000150:complications; D008875:Middle Aged; D011183:Postoperative Complications; D011184:Postoperative Period; D012189:Retrospective Studies; D014792:Visual Acuity; D014821:Vitrectomy