title: Recruitment strategies in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial: the first six years.
abstract: The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial has a total enrollment goal of almost 150,000 participants. These participants are being recruited at ten screening centers across the United States. All screening centers tested recruitment methodologies during a 1-year pilot phase. The main phase of recruitment was planned to take place over a 3-year period. The majority of participants are being recruited during the main phase of the study. Each of the screening centers tailors recruitment to its individual catchment area. Recruitment strategies in the PLCO trial are described. As the trial began, several protocol changes were made to help to increase enrollment. The National Cancer Institute (NCI) initiated recruitment efforts at the national level. The individual screening centers describe some of the specific recruitment experiences encountered. As the study progressed, the NCI implemented special initiatives to increase the enrollment of minority participants.
authors.affiliation: Early Detection Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland 20892-7346, USA.
authors.forename: N K
authors.initials: NK
authors.lastname: Simpson
authors.forename: C C
authors.initials: CC
authors.lastname: Johnson
authors.forename: S L
authors.initials: SL
authors.lastname: Ogden
authors.forename: E
authors.initials: E
authors.lastname: Gamito
authors.forename: N
authors.initials: N
authors.lastname: Trocky
authors.forename: C
authors.initials: C
authors.lastname: McGuire
authors.forename: J
authors.initials: J
authors.lastname: Martin
authors.forename: S
authors.initials: S
authors.lastname: Barrow
authors.forename: L
authors.initials: L
authors.lastname: Lamerato
authors.forename: L M
authors.initials: LM
authors.lastname: Flickinger
authors.forename: K G
authors.initials: KG
authors.lastname: Broski
authors.forename: D
authors.initials: D
authors.lastname: Engelhard
authors.forename: C
authors.initials: C
authors.lastname: Hilke
authors.forename: J
authors.initials: J
authors.lastname: Bonk
authors.forename: B
authors.initials: B
authors.lastname: Gahagan
authors.forename: L H
authors.initials: LH
authors.lastname: Gren
authors.forename: J
authors.initials: J
authors.lastname: Childs
authors.forename: K
authors.initials: K
authors.lastname: Lappe
authors.forename: M
authors.initials: M
authors.lastname: Fouad
authors.forename: J
authors.initials: J
authors.lastname: Thompson
authors.forename: D
authors.initials: D
authors.lastname: Sullivan
mesh_terms: D000368:Aged; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000517:prevention & control; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000517:prevention & control; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000517:prevention & control; D018579:Patient Selection; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000517:prevention & control; D016032:Randomized Controlled Trials as Topic