Epithelial morphogenesis: filopodia at work.
Spreading and fusion of epithelial sheets are conserved morphogenetic mechanisms that help shape embryos and tissues. Recent findings suggest that the formation of dynamic filopodia at the leading front of the epithelia plays a critical role in regulating cell movement and recognition during these processes.
Martín-Blanco
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Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Cantoblanco, Madrid 28049, Spain. emblanco@cbm.uam.es
Knust
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D000818:Animals; D017173:Caenorhabditis elegans / Q000196:embryology; D004330:Drosophila / Q000196:embryology; D004847:Epithelial Cells / Q000166:cytology*; D009024:Morphogenesis