Advances in the analysis of DNA sequence variations using oligonucleotide microchip technology.
The analysis of DNA variation (polymorphisms and mutations) on a genome-wide scale is becoming both increasingly important and technically challenging. An integration of a growing number of molecular biological methods of DNA-sequence analysis with the high-throughput feature of oligonucleotide microarray-based technologies is one of the most promising current directions of research and development.
Tillib
S V
SV
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov Str., Moscow 117984, Russia. stillib@cityline.ru
Mirzabekov
A D
AD
D001483:Base Sequence; D001709:Biotechnology / Q000379:methods; D014644:Genetic Variation; D009693:Nucleic Acid Hybridization; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D009841:Oligonucleotides; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide
D009841:Oligonucleotides