title: Pulse wave analysis in the assessment of patients with left ventricular assist device.
abstract: Central aortic pressure determines perfusion of vital organs, and its precise determination is particularly important in low-output syndromes. Because peripheral pressure values are not equal to the corresponding pressures in the aorta, we used a validated system that employs the principle of applanation tonometry for non-invasive recording of radial arterial pulse and determination of central aortic pressure waveform in patients who underwent implantation of left ventricular assist device. We observed significant improvement after assist device implantation; however, a discrepancy between peripheral and central pressure values was evident both before and after implantation. This non-invasive technique may prove particularly useful in repeat evaluation of patients in long-term follow-up and may provide valuable insights for coupling between the assist device and the vascular system.
authors.affiliation: University of New South Wales, Medical Professorial and Heart Transplant Unit, O'Brien Building, Level 17, Rm. 712, St. Vincent's Hospital, Darlinghurst NSW 2010, Sydney, Australia. cvlachop@otenet.gr
authors.forename: C
authors.initials: C
authors.lastname: Vlachopoulos
authors.forename: P
authors.initials: P
authors.lastname: Mcdonald
authors.forename: P
authors.initials: P
authors.lastname: Spratt
authors.forename: M
authors.initials: M
authors.lastname: O'Rourke
mesh_terms: D001011:Aorta; D001794:Blood Pressure / Q000502:physiology*; D006331:Heart Diseases / Q000503:physiopathology / Q000628:therapy; D006353:Heart-Assist Devices; D006801:Humans; D011674:Pulse / Q000379:methods*; D017534:Radial Artery