Primary biliary malignant lymphoma clinically mimicking cholangiocarcinoma: a case report and review of the literature.
Primary lymphomas of the liver and biliary tract are rare tumors. We describe an unusual case of a diffuse large B-cell lymphoma arising in the extrahepatic bile ducts with local extension to involve the intrahepatic bile ducts. The patient presented solely with obstructive biliary symptoms. The clinical presentation, radiographic studies, and gross findings at surgery suggested that this patient had a Klatskin tumor (cholangiocarcinoma arising at the junction of the left and right hepatic ducts). While rare, the difference in initial patient management emphasizes the importance of including malignant lymphoma in the differential diagnosis of obstructive biliary lesions. Ann Diagn Pathol 5:25-33, 2001.
Eliason
S C
SC
Department of Pathology, Wilford Hall Medical Center, TX, USA.
Grosso
L E
LE
D000328:Adult; D001650:Bile Duct Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D001653:Bile Ducts, Intrahepatic / Q000000981:diagnostic imaging / Q000473:pathology*; D014408:Biomarkers, Tumor; D018281:Cholangiocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D016133:Polymerase Chain Reaction; D011859:Radiography
D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm