title: [Determination of normal values and analysis of their relation for distortion product otoacoustic emission in guinea pigs].
abstract: In the present paper, we measured systematically the normal values of 1, 2, 4, 6 kHz distortion product otoacoustic emission (DPOAE) in guinea pigs and analyzed the relation of these values. The incidence of DPOAE in all frequencies were 100%. The amplitudes of DPOAE above 2 kHz were large than 25 dB SPL, but the amplitude of 1 kHz was lower than one of above 2 kHz. The threshold of above 2 kHz were lower than one of 1 kHz. A trend was found that latencies of all frequencies decreases accompanied with the f2 frequencies increasing. I/0 function curves demonstrated that there was a significant relation between the amplitudes of DPOAE and the levels of primary stimuli in the statistics, that is, lower levels of primary stimuli and smaller amplitudes of DPOAE. Our results indicated that a guinea pig, whose DPOAE possessed the properties of high incidence, large amplitude and stable responsibility, was an appropriate experimental animal for studying DPOAE. In addition, this paper recommended briefly the experience about the measuring techniques for DPOAE in guinea pigs.
authors.affiliation: Department of Otorhinolaryngology, Union Hospital, Tongji Medical University, Wuhan, 430022.
authors.forename: Y
authors.initials: Y
authors.lastname: Liang
authors.forename: N
authors.initials: N
authors.lastname: Zhong
mesh_terms: D000161:Acoustic Stimulation; D000818:Animals; D003051:Cochlea / Q000502:physiology*; D005260:Female; D006168:Guinea Pigs; D008297:Male; D017084:Otoacoustic Emissions, Spontaneous