Superficial esophageal carcinoma: an in vitro study of high-resolution MR imaging at 1.5T.
The purpose of this study was to determine the diagnostic accuracy of high-resolution MR imaging at 1.5T for evaluating the mural invasion of superficial esophageal carcinoma. Forty-one esophageal specimens taken from patients suspected of having superficial carcinoma were studied using a 1.5T MR system with a surface coil. Spin-echo MR images were obtained with a field of view of 50mm, matrix of 256 x 256, and section thickness of 2mm (voxel size = 0.08 mm3). MR findings were compared with histopathologic findings. T2-weighted images clearly depicted the normal esophageal wall as consisting of 8 layers. In 39 (95%) of 41 carcinomas, the depth of mural invasion determined by MR imaging correlated well with that determined with histopathologic examination. The MR-based stage was higher in 2 (5%) cases than the histopathologic stage. High-resolution MR imaging at 1.5T shows a high diagnostic accuracy for evaluating the mural invasion of superficial esophageal carcinoma, thus potentially enabling preoperative histopathologic staging.
Yamada
I
I
Department of Radiology, Faculty of Medicine, Tokyo Medical and Dental University, Tokyo, Japan. yamada.crad@med.tmd.ac.jp
Izumi
Y
Y
Kawano
T
T
Yoshino
N
N
Tetsumura
A
A
Ohashi
K
K
Shibuya
H
H
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D004947:Esophagus / Q000473:pathology; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D012680:Sensitivity and Specificity