title: Anthelmintic activity of crude aqueous extract of Nauclea latifolia stem bark against ovine nematodes.
abstract: The anthelmintic efficacy of Nauclea latifolia stem bark aqueous extract was studied in sheep with natural acute/sub-acute parasitic gastro-enteritis due primarily to mixed nematode species. Graded doses of the extract (400, 800 and 1600 mg/kg, p.o for 5 consecutive days) significantly reduced faecal egg counts in infected animals. The percentage reduction (93.8%) by 1600 mg/kg of the extract was comparable to that of 5 mg/kg of albendazole (94.1%). The administration of the extract resulted in improved haemoglobin and leucocytosis values in worm-infected sheep.
authors.affiliation: Department of Veterinary Physiology and Pharmacology, Maiduguri, Nigeria. conwosu@unimaid.edu.ng
authors.forename: P A
authors.initials: PA
authors.lastname: Onyeyili
authors.forename: C O
authors.initials: CO
authors.lastname: Nwosu
authors.forename: J D
authors.initials: JD
authors.lastname: Amin
authors.forename: J I
authors.initials: JI
authors.lastname: Jibike
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D005243:Feces / Q000469:parasitology; D005260:Female; D005759:Gastroenteritis / Q000188:drug therapy*; D008297:Male; D016488:Medicine, African Traditional; D009349:Nematode Infections / Q000188:drug therapy*; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D010946:Plants, Medicinal / Q000627:therapeutic use; D011897:Random Allocation; D019666:Rubiaceae / Q000627:therapeutic use*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy*; D014197:Trees / Q000737:chemistry
chemical_list: D000871:Anthelmintics; D010936:Plant Extracts