title: Kinetic resolution of allylic alcohols using a chiral phosphine catalyst.
abstract: [reaction: see text] The kinetic resolution of racemic allylic alcohols 3, 6, and 12--17 has been explored using the PBO catalyst 7 for activation of isobutyric anhydride. Trisubstituted allylic alcohols (12--15; 17) are the best substrates and react with an enantioselectivity of s = 32--82 at -40 degrees C.
authors.affiliation: Department of Chemistry, University of Michigan, Ann Arbor 48109, USA. edved@umich.edu
authors.forename: E
authors.initials: E
authors.lastname: Vedejs
authors.forename: J A
authors.initials: JA
authors.lastname: MacKay