The metabolic availability of dietary triacylglycerols from two high oleic oils during the postprandial period does not depend on the amount of oleic acid ingested by healthy men.
Monounsaturated oils, virgin olive oil (VOO) and high oleic sunflower oil (HOSO) are suggested to have selective physiologic effects on humans in the fasting state. The aim of the study was to evaluate whether two oils with equal amounts of oleic acid but with different compositions of minor fatty acids and triacylglycerol molecular species (TAG) could produce different triacylglycerol-rich lipoprotein (TRL)-TAG responses in the postprandial state. Eight normolipidemic men consumed the following three meals in random order on separate occasions with 2 wk between meals: control meal, control meal plus VOO and control meal plus HOSO. Plasma total TAG and TRL-TAG were measured hourly for 7 h after ingestion. TAG and sn-2 positional fatty acids within TAG were analyzed in the TRL fraction. Plasma total TAG concentrations in response to the dietary oils did not differ. However, TRL triglyceridemia was significantly lower after VOO intake (P < 0.05). The molecular species in the TRL fraction returned toward basal levels more quickly (P < 0.05) after VOO than HOSO intake. 2-Positional fatty acid analysis demonstrated higher proportions of stearic and palmitic acids and a lower proportion of oleic acid (P < 0.05) in TRL-TAG derived from HOSO. This study shows that VOO intake results in attenuated postprandial TAG concentration and faster TRL-TAG disappearance from blood compared with HOSO, suggesting that the oleic acid content may not be the main factor affecting TAG metabolism. Minor fatty acids such as linoleic acid and the 2-positional distribution of saturated stearic and palmitic acids into the TAG molecule may be important determinants of postprandial lipemia in normolipidemic men.
Abia
R
R
Instituto de la Grasa, Consejo Superior de Investigaciones Cientificas, 41012 Sevilla, Spain.
Pacheco
Y M
YM
Perona
J S
JS
Montero
E
E
Muriana
F J
FJ
Ruiz-Gutiérrez
V
V
D000328:Adult; D001682:Biological Availability; D004032:Diet; D005227:Fatty Acids / Q000032:analysis; D006801:Humans; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000737:chemistry; D008297:Male; D009829:Oleic Acids / Q000032:analysis / Q000378:metabolism*; D000069463:Olive Oil; D010938:Plant Oils / Q000737:chemistry; D019518:Postprandial Period; D012016:Reference Values; D000074242:Sunflower Oil; D014280:Triglycerides / Q000008:administration & dosage* / Q000032:analysis / Q000097:blood* / Q000737:chemistry
D005227:Fatty Acids; D008055:Lipids; D008074:Lipoproteins; D009829:Oleic Acids; D000069463:Olive Oil; D010938:Plant Oils; D000074242:Sunflower Oil; D014280:Triglycerides