title: Combined cryotherapy/70% salicylic acid treatment for plantar verrucae.
abstract: Although common, warts are inconsistently treated by any single method. The authors present a review of the literature for various treatments with regard to the methodology and success rate of each treatment modality. The authors also present a therapeutic regimen of combined cryotherapy/ 70% salicylic acid. This treatment involves in-office application of the cryogenic agent and daily application of 70% salicylic acid by the patient. The cryotherapy was combined with daily patient application of salicylic acid to increase destruction of the verruca. In a study of 29 patients with 65 warts, the authors found this method successful in 58 warts in 25 patients, showing a 89.2% rate of eradication of verrucae in 86.2% of patients. The method is recommended due to its consistent efficacy in the patient population, and its relatively gentle and noninvasive approach.
authors.affiliation: Temple University School of Podiatric Medicine, USA.
authors.forename: R L
authors.initials: RL
authors.lastname: van Brederode
authors.forename: E D
authors.initials: ED
authors.lastname: Engel
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D002648:Child; D003131:Combined Modality Therapy; D017679:Cryotherapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D005534:Foot Diseases / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D020156:Salicylic Acid / Q000627:therapeutic use*; D016896:Treatment Outcome; D014860:Warts / Q000175:diagnosis / Q000628:therapy*
chemical_list: D020156:Salicylic Acid