Reconsidering the importance of long-term low-level aluminum exposure in renal failure patients.
Aluminum toxicity is widely considered a problem of the past. However, low-level aluminum exposure and low but abnormal body burdens of aluminum are common. Aluminon, the routinely used histochemical stain for aluminum in bone, has a low sensitivity. The role of aluminum in renal osteodystrophy needs to be reassessed using more sensitive techniques. Low-level aluminum exposure also may resu in subtle neurological dysfunction, another area that needs further investigation.
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D000535:Aluminum / Q000009:adverse effects*; D003704:Dementia / Q000139:chemically induced; D015312:Hemodialysis Solutions / Q000009:adverse effects*; D006801:Humans; D015994:Incidence; D008991:Monitoring, Physiologic / Q000379:methods; D011379:Prognosis; D006435:Renal Dialysis / Q000009:adverse effects; D051437:Renal Insufficiency / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D018570:Risk Assessment; D012307:Risk Factors
D015312:Hemodialysis Solutions; D000535:Aluminum