Determination of lewisite oxide in soil using solid-phase microextraction followed by gas chromatography with flame photometric or mass spectrometric detection.
A rapid, sensitive, and convenient method is described for determining Lewisite oxide in soil. Samples are initially fortified with phenylarsine oxide (surrogate), then both species are extracted using ascorbic acid solutions containing 1,3-propanedithiol (derivatizing reagent). The corresponding filtered supernatant is sampled using a solid-phase microextraction fiber. Collected analytes are thermally desorbed in a heated gas chromatographic inlet, separated using fused-silica capillary columns ("primary" and "confirmatory"), and detected with either a mass spectrometric (selected ion monitoring mode) or flame photometric (sulfur-selective mode) detector. Two independent statistically-unbiased procedures were used to evaluate the detection limit for Lewisite oxide; the values range between 0.1 and 0.5 microg g(-1) soil.
Tomkins
B A
BA
Chemical and Analytical Sciences Division, Oak Ridge National Laboratory, TN 37831-6120, USA. tomkinsba@ornl.gov
Sega
G A
GA
Ho
C H
CH
D001152:Arsenicals / Q000032:analysis*; D002138:Calibration; D002849:Chromatography, Gas / Q000379:methods*; D008401:Gas Chromatography-Mass Spectrometry; D013058:Mass Spectrometry; D010783:Photometry; D012680:Sensitivity and Specificity; D012987:Soil / Q000032:analysis*; D013997:Time Factors
D001152:Arsenicals; D012987:Soil; C035965:lewisite