Adverse granulomatous reaction after cosmetic dermal silicone injection.
BACKGROUND
Various alloplastic injectable implants have been developed for soft tissue augmentation without surgery, but different local or systemic adverse reactions have limited their use for cosmetic purposes.


OBJECTIVE
To examine the problems associated with silicone injection.


METHODS
Case report and literature review.


RESULTS
We describe an adverse granulomatous reaction after the injection of liquid silicone for lip augmentation, causing facial disfigurement. Although the initial response to steroids was poor, after 3 years of follow-up the nodules have almost disappeared spontaneously.


CONCLUSIONS
We advise that silicone injection be performed solely by trained physicians using medical-grade silicone or consider other injectable materials.
Bigatà
X
X
Department of Dermatology, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain.
Ribera
M
M
Bielsa
I
I
Ferrándiz
C
C
D003357:Cosmetic Techniques / Q000009:adverse effects*; D020405:Dermis / Q000473:pathology; D005260:Female; D015745:Granuloma, Foreign-Body / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007279:Injections, Subcutaneous; D008046:Lip; D008875:Middle Aged; D012828:Silicones / Q000008:administration & dosage / Q000009:adverse effects*
D012828:Silicones