Pseudoexfoliation syndrome and aneurysms of the abdominal aorta.
We assessed the association between pseudoexfoliation syndrome, a common age-related fibrillopathy of unknown cause, and vascular diseases, especially aneurysms of the abdominal aorta. In a prospective single-blind study we ophthalmoscopically examined 55 patients with aneurysms of the abdominal aorta and 41 controls with carotic-artery occlusion. 24 of 55 patients with aortic aneurysm showed signs of manifest (17 of 55 patients) or early-stage (seven of 55) pseudoexfoliation syndrome. Eight of 41 control patients showed manifest (seven of 41 patients) and early (one of 41) ocular pseudoexfoliation (p=0.016). These findings, including histopathological examinations, suggest an association between aneurysms of the abdominal aorta and pseudoexfoliation syndrome.
Schumacher
S
S
Schlötzer-Schrehardt
U
U
Martus
P
P
Lang
W
W
Naumann
G O
GO
D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000453:epidemiology* / Q000473:pathology; D016022:Case-Control Studies; D017889:Exfoliation Syndrome / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D011446:Prospective Studies; D016037:Single-Blind Method