title: Alternate exon in the 5'-untranslated region of the human ACTH receptor gene.
abstract: The human ACTH receptor (ACTH-R) gene consists of two exons; the first encodes the 5'-untranslated region (UTR) and the second encodes part of the 5'-UTR, the entire coding region, and the whole of the 3'-UTR. While investigating the transcription initiation site of the human ACTH-R gene by 5'-rapid amplification of cDNA ends, we found a 157-bp alternate exon in the 5'-UTR. This newly identified exon was irrelevant to the alternate exon in the mouse ACTH-R gene which we reported previously.
authors.affiliation: Health Administration Center, Hokkaido University of Education, Sapporo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kubo
authors.forename: C
authors.initials: C
authors.lastname: Shimizu
authors.forename: H
authors.initials: H
authors.lastname: Kijima
authors.forename: T
authors.initials: T
authors.lastname: Ishizuka
authors.forename: K
authors.initials: K
authors.lastname: Takano
authors.forename: A
authors.initials: A
authors.lastname: Takano
authors.forename: T
authors.initials: T
authors.lastname: Koike
mesh_terms: D020121:5' Untranslated Regions; D017398:Alternative Splicing; D001483:Base Sequence; D004587:Electrophoresis, Agar Gel; D005091:Exons; D006801:Humans; D008969:Molecular Sequence Data; D021141:Nucleic Acid Amplification Techniques; D016133:Polymerase Chain Reaction / Q000379:methods; D018043:Receptors, Corticotropin / Q000235:genetics*
chemical_list: D020121:5' Untranslated Regions; D018043:Receptors, Corticotropin