title: Isolated splenic metastasis from gastric carcinoma: value of CEA and CA 19-9 in early diagnosis: report of two cases.
abstract: We report two cases of an isolated splenic metastasis, occurring 5 and 3 years, respectively, after gastrectomy for gastric carcinoma. Serum carcinoembryonic antigen and CA 19-9 levels were evaluated preoperatively, postoperatively, and during the oncologic follow-up. The patients underwent splenectomy for solitary splenic metastasis. We conclude that the use of serum carcinoembryonic and CA 19-9 values may help in the early diagnosis of these recurrences and splenectomy allows radical treatment in patients with no evidence of disseminated disease.
authors.affiliation: Department of Surgery, University of Milan, Ospedale San Paolo, Milano, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Opocher
authors.forename: R
authors.initials: R
authors.lastname: Santambrogio
authors.forename: P
authors.initials: P
authors.lastname: Bianchi
authors.forename: U
authors.initials: U
authors.lastname: Cioffi
authors.forename: M
authors.initials: M
authors.lastname: De Simone
authors.forename: S
authors.initials: S
authors.lastname: Vellini
authors.forename: M
authors.initials: M
authors.lastname: Montorsi
mesh_terms: D000230:Adenocarcinoma / Q000097:blood* / Q000175:diagnosis / Q000556:secondary*; D000368:Aged; D018395:CA-19-9 Antigen / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000097:blood*; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D013160:Splenic Neoplasms / Q000097:blood* / Q000175:diagnosis / Q000556:secondary*; D013274:Stomach Neoplasms / Q000097:blood* / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery
chemical_list: D018395:CA-19-9 Antigen; D002272:Carcinoembryonic Antigen