title: [Use of cefuroxime axetil in clinical practice].
abstract: This study summarizes the actual recommendations for cefuroxime axetil treatment in dermatology and general medicine. These include the well known clinical efficacies in therapy of upper and lower respiratory tract infections, genitourinary tract infections and skin and soft tissue infections, but also connective tissue diseases, such as morphea and SCLE. Though the immunomodulatory activity of the drug should be established by further controlled studies, there are some limited literature data, which show the modulatory effect of cefuroxime axetil on the lymphocyte proliferation and the production of selected cytokines.
authors.affiliation: Kliniki Dermatologii Centrainego Szpitala Kiinicznego MSWiA w Warszawie.
authors.forename: M
authors.initials: M
authors.lastname: Słowińska
authors.forename: E
authors.initials: E
authors.lastname: Szymańska
authors.forename: I
authors.initials: I
authors.lastname: Walecka
authors.forename: L
authors.initials: L
authors.lastname: Rudnicka
mesh_terms: D001424:Bacterial Infections / Q000188:drug therapy; D001899:Borrelia Infections / Q000188:drug therapy; D002444:Cefuroxime / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use*; D003240:Connective Tissue Diseases / Q000188:drug therapy; D016207:Cytokines / Q000096:biosynthesis / Q000187:drug effects; D003872:Dermatitis / Q000188:drug therapy; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects; D012141:Respiratory Tract Infections / Q000188:drug therapy
chemical_list: D016207:Cytokines; D002444:Cefuroxime; C040738:cefuroxime axetil
vernacular_title: Zastosowanie aksetylu cefuroksymu w praktyce klinicznej.