title: [Endocrinological parameters of patients with acute progressive pulmonary tuberculosis].
abstract: Examining the levels of the hormones insulin and cortisole that play a significant role in nonspecific protection in tuberculosis indicates the heterodirectional pattern of changes in endocrinological parameters in relation to the clinical form of acute progressive tuberculosis. In drug-treated patients with caseous pneumonia, the high level of cortisole decreased and the content of insulin reached the lower normal range with 18.2% of cases having hypoinsulinemia. Patients with disseminated pulmonary tuberculosis had an inversely proportion ratio of the hormones, which reflected the specific features of acute progression of this clinical form. In acute progressive infiltrative tuberculosis, the levels of cortisole and insulin significantly increased during chemotherapy. Nevertheless, whatever changes were observed in hormonal levels, variations in the parameters indicate the long-term activity of specific inflammation in acute progressive pulmonary tuberculosis.
authors.forename: G S
authors.initials: GS
authors.lastname: Balasaniants
authors.forename: M S
authors.initials: MS
authors.lastname: Greĭmer
authors.forename: L S
authors.initials: LS
authors.lastname: Shpanskaia
mesh_terms: D000208:Acute Disease; D015415:Biomarkers / Q000097:blood; D018450:Disease Progression; D004703:Endocrine System / Q000378:metabolism*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D007328:Insulin / Q000097:blood*; D012720:Severity of Illness Index; D014397:Tuberculosis, Pulmonary / Q000097:blood*
chemical_list: D015415:Biomarkers; D007328:Insulin; D006854:Hydrocortisone
vernacular_title: Pokazateli éndokrinnogo statusa u bol'nykh ostro progressiruiushchim tuberkulezom legkikh.