title: Denture-induced fibrous inflammatory hyperplasia: a retrospective study in a school of dentistry.
abstract: OBJECTIVE
  The aim of this study was to investigate the denture-induced fibrous inflammatory hyperplasia (FIH) that occurs around the borders of an ill-fitting denture, in relation to frequency of the lesion, age and sex distribution, length of denture use, and frequency of dysplasia.
  
  
  METHODS
  A comprehensive review of FIH diagnosed in patients wearing dentures by the oral pathology diagnostic service at the University of São Paulo over 26 years (1971 to 1996) was undertaken, based on retrospective analysis of the oral histopathologic files.
  
  
  RESULTS
  The frequency of FIH was 15% of the total number of pathologies diagnosed at the service of oral pathology in that period. The disorder occurred predominantly in the fifth and sixth decades of life and more often among females, at a proportion of 5:1. The frequency of FIH was higher for a length of denture use of between 1 and 10 years. Dysplasia was found in 4% of cases.
  
  
  CONCLUSIONS
  The knowledge of some aspects of FIH, especially the possible histologic alteration of dysplasia, supports the importance of the diagnosis and treatment of the lesion and suggests that any excised tissue should be submitted to histopathologic evaluation. Education and regular review of patients who have worn dentures are essential if the development of FIH is to be prevented.
authors.affiliation: Department of Pathology, Medical School of Ribeirão Preto, University of São Paulo, 14049-900 Ribeirão Preto, São Paulo, Brazil. claudiacoelho@zaz.com.br
authors.forename: C M
authors.initials: CM
authors.lastname: Coelho
authors.forename: S
authors.initials: S
authors.lastname: Zucoloto
authors.forename: R A
authors.initials: RA
authors.lastname: Lopes
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D003778:Dentures / Q000009:adverse effects*; D005260:Female; D005355:Fibrosis; D005500:Follow-Up Studies; D006801:Humans; D006965:Hyperplasia; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic; D012189:Retrospective Studies; D012575:Schools, Dental; D012737:Sex Factors; D013282:Stomatitis, Denture / Q000453:epidemiology* / Q000473:pathology; D013997:Time Factors