title: Merkel cell carcinoma of the eyebrow extending into the orbit.
abstract: BACKGROUND
  Merkel cell carcinoma is a rare and aggressive cutaneous neoplasm with high local recurrence and metastatic rates.
  
  
  OBJECTIVE
  To highlight an unusual presentation of a Merkel cell carcinoma.
  
  
  METHODS
  We report a large Merkel cell tumor in an 85-year-old woman. It extended from the eyebrow into the upper nasal orbit posterior to the equator of the eye globe. Local resection resulted in microscopically complete removal of the tumor. During follow-up (20 months) no local recurrence was noticed but there was a metastasis in a lymphatic nodule.
  
  
  CONCLUSIONS
  Merkel cell carcinoma often presents in the eyelids and periorbital region. However, extension from the eyebrow deep into the orbit is unusual.
authors.affiliation: Department of Ophthalmology, Marienhospital Osnabruck, Academic Teaching Hospital of the Medical University Hannover, Osnabruck, Germany. Dr.Sieberth@T-Online.de
authors.forename: V
authors.initials: V
authors.lastname: Seiberth
authors.forename: C
authors.initials: C
authors.lastname: Woldt
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015266:Carcinoma, Merkel Cell / Q000556:secondary* / Q000601:surgery; D005134:Eye Neoplasms / Q000473:pathology* / Q000601:surgery; D005138:Eyebrows; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging; D009918:Orbital Neoplasms / Q000556:secondary* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery