[Intravesical chemotherapy with mitomycin C after TUR for superficial bladder carcinoma].
Fifty-four patients mean aged 58.5 years (28 women and 26 men) undergo transurethral resection for superficial bladder carcinoma. Postoperatively 20 mg mitomycin is administered by instillation into the bladder for 8 weeks. Preoperative assessment includes: complete blood count, urea, creatinine, isotope nephrography, ultrasonography, excretory urography and CT scan of pelvis. Multifocal lesions are diagnosed in 22 patients (40.7%). In 36 cases (66.7%) it is a matter of solitary papillomas. The distribution of lesions is as follows: left bladder wall--12 patients (22.2%), right bladder wall--13 (24.07 per cent), trigone--18 (33.3%), and anterior bladder wall--11 (20.03 per cent). Postoperative check-ups: cytological assessment of urine and regular endoscopic study at 3-6 months. Recurrence rate amounts to 42.5% for the maximum follow-up period.
Neykov
K
K
Medical University, Department of Urology, Sofia, Bulgaria.
Donkov
I
I
Mirchov
R
R
D000283:Administration, Intravesical; D000368:Aged; D002277:Carcinoma / Q000188:drug therapy* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage*; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D012189:Retrospective Studies; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy* / Q000601:surgery
D016685:Mitomycin
Adiuvantna lokalna khimioterapiia s mitomitsin C pri pov'rkhnostni kartsinomi na pikochniia mekhur.