title: Secondary caries and restoration replacement: an unresolved problem.
abstract: This article reviews the prevalence and main causes of restoration failure and replacement. It then focuses on secondary caries, its histopathology, etiology, difficulties in diagnosis, and prevention and remineralization possibilities. This article concludes that although secondary caries is still the main reason for restoration replacement, the development of new technologies for detecting and monitoring these lesions at an early stage should allow for testing new interventions to arrest or remineralize these lesions, which would delay the need for re-restoration.
authors.affiliation: Oral Health Research Institute, Indiana University School of Dentistry, Indianapolis, Indiana, USA.
authors.forename: M
authors.initials: M
authors.lastname: Fontana
authors.forename: C
authors.initials: C
authors.lastname: González-Cabezas
mesh_terms: D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use; D002327:Cariostatic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003188:Composite Resins; D003723:Dental Amalgam; D003731:Dental Caries / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control / Q000628:therapy; D003793:Dental Restoration, Permanent / Q000009:adverse effects; D003937:Diagnosis, Differential; D006801:Humans; D012008:Recurrence; D019233:Retreatment; D013499:Surface Properties; D013674:Technology, Dental; D014089:Tooth Remineralization
chemical_list: D000891:Anti-Infective Agents, Local; D002327:Cariostatic Agents; D003188:Composite Resins; D003723:Dental Amalgam