[Histological and immunohistochemical characteristics of diffuse large cell B-cell lymphomas].
In the REAL classification, diffuse large B-cell non-Hodgkin's lymphomas are grouped together. We investigated histological variants and immunohistochemical profile of diffuse large B-cell lymphomas in 53 patients. Accuracy of the diagnosis was 73.6% without immunohistochemistry. The usefulness of immunophenotyping in making the correct diagnosis depended on a specific histological variant of diffuse large B-cell lymphoma. Variants with polymorphic and anaplastic morphology or massive reactive component have been diagnosed by routine histological methods with poor validity.
Krivolapov
Iu A
IuA
St-Petersburg Medical Academy of Advanced Medical Education, 193015, St-Petersburg.
Saltykova
L B
LB
Kozlova
A A
AA
D000328:Adult; D014408:Biomarkers, Tumor; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000378:metabolism* / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000378:metabolism* / Q000473:pathology*; D008297:Male; D008875:Middle Aged
D014408:Biomarkers, Tumor
Gistologicheskaia i immunogistokhimicheskaia kharakteristika diffuznykh krupnokletochnykh B-kletochnykh limfom.