[Idiopathic pulmonary fibrosis: a new histopathologic classification and clinical aspects].
Idiopathic pulmonary fibrosis (IPF) comprises different interstitial lung diseases of unknown origin. They are classified into four groups based on pathologic criteria: UIP, DIP, AIP and NSIP. This classification helps in terms of prognosis and treatment. In addition to history, physical examination and common investigations (chest X ray, pulmonary function testing), a bronchoalveolar lavage (BAL), a high-resolution CT scan and ideally a open-lung biopsy are needed to establish a precise diagnosis. The patients are usually treated by immunosuppressive agents, and mainly by corticoids. However, in UIP, lung transplantation is the only way to improve survival.
Blaise
P
P
Université de Liège, Service de Pneumologie.
Louis
R
R
Bartsch
P
P
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D001992:Bronchoalveolar Lavage Fluid; D001999:Bronchoscopy; D005260:Female; D006801:Humans; D016040:Lung Transplantation; D008297:Male; D008487:Medical History Taking; D008875:Middle Aged; D010808:Physical Examination; D011379:Prognosis; D011658:Pulmonary Fibrosis / Q000145:classification* / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D012129:Respiratory Function Tests; D013256:Steroids; D016019:Survival Analysis
D000893:Anti-Inflammatory Agents; D013256:Steroids
Les fibroses pulmonaires idiopathiques: nouvelle classification histopathologique et aspects cliniques.