Transient ST segment elevation in right precordial leads induced by psychotropic drugs: relationship to the Brugada syndrome.
Psychotropic Drugs and ST Segment Elevation. Transient ST segment elevation in right precordial leads with use of psychotropic drugs is reported in two cases of overdose and one case of therapeutic administration. Flecainide did not reproduce ST segment elevation. The relationship of these abnormalities to the Brugada syndrome and the electrophysiologic hypothesis are discussed.
Rouleau
F
F
Département de Cardiologie, Centre Hospitalier Universitaire d'Angers, France.
Asfar
P
P
Boulet
S
S
Dube
L
L
Dupuis
J M
JM
Alquier
P
P
Victor
J
J
D000328:Adult; D000639:Amitriptyline / Q000009:adverse effects; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000009:adverse effects; D002037:Bundle-Branch Block / Q000150:complications / Q000503:physiopathology; D016757:Death, Sudden, Cardiac / Q000209:etiology; D004562:Electrocardiography; D005260:Female; D005473:Fluoxetine / Q000009:adverse effects; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010640:Phenothiazines / Q000009:adverse effects; D011619:Psychotropic Drugs / Q000009:adverse effects*; D013577:Syndrome; D013997:Time Factors
D018687:Antidepressive Agents, Second-Generation; D000929:Antidepressive Agents, Tricyclic; D014150:Antipsychotic Agents; D010640:Phenothiazines; D011619:Psychotropic Drugs; D005473:Fluoxetine; D000639:Amitriptyline; C028457:cyamemazine