Ibopamine treatment in chronic hypotony secondary to long-lasting uveitis. A case report.
OBJECTIVE
To assess the clinical efficacy of ibopamine eye drops in severe hypotony secondary to chronic progressive uveitis.


METHODS
Case report. A 47-year-old man with a 37-year history of diffuse uveitis and severe refractory hypotony was treated with topical 2% ibopamine (Trazyl) six times a day. Intraocular pressure, visual acuity, visual field and side effects were recorded during 15 months of follow-up.


RESULTS
IOP, visual acuity and visual field increased after four days of therapy and lasted for two months when the drug was suspended because of the onset of filamentous keratopathy. A new course of treatment with 2% ibopamine eye drops in a different solvent (BSS) resulted in a stable increase in IOP, VA and visual field, with no side effects in a follow-up of 13 months.


CONCLUSIONS
Ibopamine 2% eye drops in BSS solvent seem effective in the treatment of uveitis-related hypotony.
Pivetti-Pezzi
P
P
Institute of Ophthalmology, University of Roma La Sapienza, Italy.
Da Dalt
S
S
La Cava
M
M
Pinca
M
M
De Gregorio
F
F
Virno
M
M
D002908:Chronic Disease; D003846:Deoxyepinephrine / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D018491:Dopamine Agonists / Q000627:therapeutic use*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D015814:Ocular Hypotension / Q000188:drug therapy* / Q000209:etiology; D009883:Ophthalmic Solutions; D014605:Uveitis / Q000150:complications*; D014792:Visual Acuity / Q000187:drug effects; D014794:Visual Fields / Q000187:drug effects
D018491:Dopamine Agonists; D009883:Ophthalmic Solutions; C023487:ibopamine; D003846:Deoxyepinephrine