[Structural changes in the brain in HIV infection complicated by drug addiction].
Comparative analysis of brain alterations in drug addicts who were HIV-seropositive and died of sepsis and HIV-seronegative addicts showed similarity of these changes which manifested with ganglion cell rarefaction and losses, changed neuron content of main structural-functional types; massive satellitosis and neuronophagia, massive glycosis and leucodystrophy. These changes were diffuse in seropositive patients and rather focal in seronegative patients. The authors, on the basis of these findings, suggest a wider spread of HIV infection in drug addicts; they express doubts in the secondary nature of HIV-encephalopathy and believe that drug addiction should be considered as factor promoting HIV-infection development.
Nasibullin
B A
BA
Ukranian Research Institute of Medical Rehabilitation and Health Resort Treatment, 270014, Odessa.
Tkachev
O V
OV
Voĭno-Iasenetskaia
O V
OV
Pykhteev
D M
DM
D001921:Brain / Q000473:pathology*; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000150:complications / Q000473:pathology*; D006801:Humans; D019966:Substance-Related Disorders / Q000150:complications / Q000473:pathology*
Osobennosti strukturnykh izmeneniĭ golovnogo mozga pri sochetanii VICh infektsii i narkomanii.