Study of protein profile in the visceral leishmaniasis.
A study of the ten proteins of the protein profile in 7 children infected with visceral leishmaniasis leads to obtain an evocating diagram of the protein profile in this disease. In these patients, the authors have found the association of a polyconal hypergammaglobulinaemia, an inflammatory syndrom (increase of orosomucoid, CRP, alpha-1-antitrypsin, decrease of albumin, prealbumin and transferrin), and an haemolytic syndrom (decrease of haptoglobin). Such a diagram may be an supplementary help to establish the diagnosis of visceral leishmaniasis, in some cases when it is difficult to find the parasites.
Bouree
P
P
Department of Parasitology and Tropical Diseases, Paris XI University, Bicetre Hospital, 78, rue du Général Leclerc F-94275 Kremlin-Bicetre, France.
Botterel
F
F
Lancon
A
A
D001798:Blood Proteins / Q000737:chemistry*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007223:Infant; D007898:Leishmaniasis, Visceral / Q000097:blood*; D008297:Male
D001798:Blood Proteins; D007136:Immunoglobulins