title: [Structure and function of thyroid hormone receptors].
abstract: The new data concerning the structure of nuclear receptor of thyroid hormone and peculiarities of its functioning as a ligand-dependent transcriptional factor are reviewed. Considerable attention is concentrated on the analysis of mechanisms of receptor interactions with specifical DNA regions which mediate iodothyronine influence on the gene expression and factors that participate in regulation of these mechanisms.
authors.forename: G L
authors.initials: GL
authors.lastname: Antoniak
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Ignatenko
authors.forename: N O
authors.initials: NO
authors.lastname: Babich
authors.forename: V V
authors.initials: VV
authors.lastname: Snitinskii
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000737:chemistry / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans; D008024:Ligands; D011988:Receptors, Thyroid Hormone / Q000737:chemistry* / Q000378:metabolism*; D013970:Thyronines / Q000378:metabolism; D014157:Transcription Factors / Q000737:chemistry* / Q000378:metabolism
chemical_list: D008024:Ligands; D011988:Receptors, Thyroid Hormone; D013970:Thyronines; D014157:Transcription Factors
vernacular_title: Struktura i funktsii retseptorov tireoidn'ikh gormonov.