CD7-specific single chain Fv immunotoxins. Design and expression.
Pennell
C A
CA
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.
Pauza
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ME
D000818:Animals; D000911:Antibodies, Monoclonal; D019011:Antigens, CD7 / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000276:immunology; D001854:Bone Marrow Cells / Q000276:immunology; D002448:Cell Adhesion; D003001:Cloning, Molecular / Q000379:methods; D005784:Gene Amplification; D005803:Genes, Immunoglobulin; D005813:Genes, Synthetic; D006801:Humans; D006825:Hybridomas / Q000378:metabolism; D007128:Immunoglobulin Fragments / Q000737:chemistry / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D007143:Immunoglobulin Heavy Chains / Q000235:genetics; D007135:Immunoglobulin Variable Region / Q000235:genetics; D007145:Immunoglobulin kappa-Chains / Q000235:genetics; D000922:Immunotoxins / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification / Q000627:therapeutic use; D007694:Killer Cells, Natural / Q000276:immunology; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000276:immunology; D051379:Mice; D016133:Polymerase Chain Reaction; D011993:Recombinant Fusion Proteins / Q000276:immunology / Q000302:isolation & purification; D012276:Ricin / Q000737:chemistry* / Q000302:isolation & purification; D013601:T-Lymphocytes / Q000276:immunology
D000911:Antibodies, Monoclonal; D019011:Antigens, CD7; D000951:Antigens, Neoplasm; C425946:DA7 immunotoxin; D007128:Immunoglobulin Fragments; D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region; D007145:Immunoglobulin kappa-Chains; D000922:Immunotoxins; D011993:Recombinant Fusion Proteins; D012276:Ricin