Neurological signs in a horse due to metastases of an intestinal adenocarcinoma.
A 22-year-old Dutch Warmblood mare was referred to Utrecht University with progressive left hind limb paresis and hyporeflexia. The preliminary clinical diagnosis was the neurological form of equine herpes virus (EHV-1) infection. Within 1 day of admission, the mare became recumbent and deteriorated rapidly. Postmortem examination revealed an adenocarcinoma of the caecum, with metastases in all regional lymph nodes and extending from the lumbar nodes into the vertebral canal, causing spinal cord compression and destruction of the left 4th and 5th lumbar nerves.
Spoormakers
T J
TJ
Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, The Netherlands.
IJzer
J
J
Sloet van Oldruitenborgh-Oosterbaan
M M
MM
D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary / Q000662:veterinary*; D000818:Animals; D002430:Cecal Neoplasms / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D006736:Horses; D008159:Lumbar Vertebrae / Q000473:pathology; D008207:Lymphatic Metastasis; D013115:Spinal Canal / Q000473:pathology; D013117:Spinal Cord Compression / Q000209:etiology / Q000503:physiopathology / Q000662:veterinary*; D013125:Spinal Neoplasms / Q000150:complications / Q000556:secondary / Q000662:veterinary*