title: [Migraine: dynamics of psychophysiologic pattern].
abstract: 85 patients with migraine without aura and 20 healthy individuals were examined between the attacks, before the attack, during and after it (1-2 days). The examination included clinical-neurological analysis; psychological Spilberger's and Beck's tests, scale of alexithymia and complex algesic questionnaire; recording of the conditional negative wave; determination of nociceptive flexor reflex; recording of trigeminal evoked potentials; spectral analysis of the heart's rhythms; polysomnographic study. Psychophysiologic pattern characteristic for all the patients was established. Psychological and neurophysiological parameters changed synchronously in the periods before the attack, during and after it. Before the migraineous attack a specific pathologic integration increased and presented maximally (the activity of antinociceptive system weakens anxiety increased, tension of catecholaminergic systems grew, hyperactivity in trigeninal sphere elevated, tolerance to the pain decreased). A clear tendency to the reversibility of these changes was observed after an attack. A dynamics revealed in the psychophysiological pattern could serve as a predictor of a migraineous attack and open some perspectives for prophylaxis of the algesic attack.
authors.forename: A M
authors.initials: AM
authors.lastname: Veĭn
authors.forename: A B
authors.initials: AB
authors.lastname: Danilov
authors.forename: O A
authors.initials: OA
authors.lastname: Kolosova
authors.forename: T G
authors.initials: TG
authors.lastname: Voznesenskaia
authors.forename: Ia I
authors.initials: IaI
authors.lastname: Levin
authors.forename: G R
authors.initials: GR
authors.lastname: Tabeeva
authors.forename: N B
authors.initials: NB
authors.lastname: Khaspekova
authors.forename: A B
authors.initials: AB
authors.lastname: Danilov
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Chernyshev
authors.forename: M S
authors.initials: MS
authors.lastname: Siniachkin
authors.forename: O V
authors.initials: OV
authors.lastname: Vornovskaia
authors.forename: I B
authors.initials: IB
authors.lastname: Fokin
mesh_terms: D001007:Anxiety / Q000523:psychology; D002395:Catecholamines / Q000378:metabolism; D005071:Evoked Potentials / Q000502:physiology; D006801:Humans; D008881:Migraine Disorders / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology*; D017286:Polysomnography; D012720:Severity of Illness Index; D012895:Sleep, REM / Q000502:physiology; D011795:Surveys and Questionnaires; D014276:Trigeminal Nerve / Q000502:physiology
chemical_list: D002395:Catecholamines
vernacular_title: Migren': dinamika psikhofiziologicheskogo patterna.