title: Animal models of Huntington's disease: from basic research on neuronal death to assessment of new therapeutic strategies.
authors.affiliation: URA CEA-CNRS 2210, Service hospitalier Frédéric Joliot, CEA, DRM, DSV, 4 place du Général Leclerc, 91401 Orsay, France.
authors.forename: E
authors.initials: E
authors.lastname: Brouillet
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology; D001284:Atrophy / Q000473:pathology; D002540:Cerebral Cortex / Q000378:metabolism; D020934:Ciliary Neurotrophic Factor / Q000627:therapeutic use*; D003072:Cognition Disorders / Q000175:diagnosis; D003342:Corpus Striatum / Q000378:metabolism / Q000473:pathology; D004195:Disease Models, Animal; D000071058:Huntingtin Protein; D006816:Huntington Disease / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology*; D008251:Macaca; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D008928:Mitochondria / Q000378:metabolism / Q000473:pathology; D009069:Movement Disorders / Q000175:diagnosis; D009410:Nerve Degeneration / Q000473:pathology*; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism; D010215:Papio; D017354:Point Mutation / Q000235:genetics; D051381:Rats; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism; D019680:Trinucleotide Repeat Expansion / Q000235:genetics
chemical_list: D020934:Ciliary Neurotrophic Factor; C506812:Htt protein, mouse; C499524:Htt protein, rat; D000071058:Huntingtin Protein; D009419:Nerve Tissue Proteins; D018696:Neuroprotective Agents; D009687:Nuclear Proteins; D016194:Receptors, N-Methyl-D-Aspartate