title: Histoplasmosis: an unusual presentation.
abstract: Histoplasma capsulatum (HC) infection is rare in India. We document a case of unilateral adrenal histoplasmosis in a 56 year male. The patient presented with hepatosplenomegaly, unilateral adrenal mass and significant weight loss. Since FNAC of adrenal mass was inconclusive, he underwent splenectomy, adrenalectomy and liver biopsy, histology of these specimens revealed HC only in adrenal mass. Subsequently, histoplasmin test was also performed which was also found to be positive. He responded well to parenteral amphotericin B and is under regular follow-up with no complaints now.
authors.affiliation: Department of Endocrinology, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005.
authors.forename: S K
authors.initials: SK
authors.lastname: Singh
authors.forename: S K
authors.initials: SK
authors.lastname: Bhadada
authors.forename: S K
authors.initials: SK
authors.lastname: Singh
authors.forename: O P
authors.initials: OP
authors.lastname: Sharma
authors.forename: N C
authors.initials: NC
authors.lastname: Arya
authors.forename: V K
authors.initials: VK
authors.lastname: Shukla
authors.forename: J K
authors.initials: JK
authors.lastname: Agrawal
mesh_terms: D000307:Adrenal Gland Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006529:Hepatomegaly / Q000382:microbiology; D006659:Histoplasmin; D006660:Histoplasmosis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D013163:Splenomegaly / Q000382:microbiology; D015431:Weight Loss
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B; D006659:Histoplasmin