Antiflammin peptides in the regulation of inflammatory response.
This review focuses on the role of antiflammins in the regulation of the inflammatory response, in particular acute inflammation. The results show that antiflammins were effective on several classical models of inflammation. Preliminary data suggest that antiflammin action may be due to their ability to suppress leukocyte trafficking to the lesion.
Moreno
J J
JJ
Department of Physiology, Faculty of Pharmacy, Barcelona University, Avda. Joan XXIII s/n, E-08028 Barcelona, Spain. moreno@farmacia.far.ub.es
D000208:Acute Disease / Q000628:therapy; D000818:Animals; D002464:Cell Migration Inhibition; D004195:Disease Models, Animal; D006801:Humans; D007249:Inflammation / Q000188:drug therapy* / Q000276:immunology / Q000503:physiopathology; D007962:Leukocytes / Q000166:cytology / Q000187:drug effects / Q000276:immunology; D009842:Oligopeptides / Q000494:pharmacology*; D010446:Peptide Fragments / Q000494:pharmacology*; D014598:Uteroglobin / Q000494:pharmacology*
D009842:Oligopeptides; D010446:Peptide Fragments; C064645:antiflammin P1; C064647:antiflammin P2; D014598:Uteroglobin