title: The evolving role of irinotecan: a broad-spectrum chemotherapeutic agent. Introduction.
authors.affiliation: Department of GI Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Ajani
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D002166:Camptothecin / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D017326:Clinical Trials, Phase III as Topic; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D006801:Humans; D000077146:Irinotecan; D009369:Neoplasms / Q000188:drug therapy*; D059004:Topoisomerase I Inhibitors
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004791:Enzyme Inhibitors; D059004:Topoisomerase I Inhibitors; D000077146:Irinotecan; D002166:Camptothecin