Diterpenoids from Azorella yareta and their trichomonicidal activities.
Diterpenoids with trichomonicidal activity were isolated from the aerial parts of Azorella yareta Hauman. One was 13beta-hydroxyazorellane, together with the known constituents mulinolic acid, mulin-11,13-dien-20-oic acid, azorellanol and 13alpha-hydroxyazorellane. Their structures were determined by spectroscopic and chemical methods.
Loyola
L A
LA
Departamento de Química, Facultad de Ciencias Básicas, Universidade de Antofagasta, Chile. aloyola@uantof.cl
Bórquez
J
J
Morales
G
G
Araya
J
J
González
J
J
Neira
I
I
Sagua
H
H
San-Martín
A
A
D000818:Animals; D000981:Antiprotozoal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019684:Magnoliopsida / Q000737:chemistry*; D014246:Trichomonas vaginalis / Q000187:drug effects*
D000981:Antiprotozoal Agents; D004224:Diterpenes