Radiation therapy for extensive actinic keratosis.
Actinic keratosis in the most common premalignant keratotic tumour of sun-exposed skin. A 66-year-old man developed a large actinic keratosis on his scalp, which did not respond to conventional treatment. Fractionated radiotherapy with a cumulative dose of 28 Gy resulted in complete remission without relapse during a 14-month follow-up. In older subjects in whom conventional treatment fails, low-dose fractionated radiation therapy is an effective alternative method.
Barta
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Department of Dermatology and Allergology, Friedrich-Schiller-University of Jena, Germany. barta@derma.uni-jena.de
Gräfe
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Wollina
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D000368:Aged; D019583:Dose Fractionation, Radiation; D006801:Humans; D007642:Keratosis / Q000209:etiology / Q000532:radiotherapy*; D008297:Male; D012535:Scalp; D013472:Sunlight / Q000009:adverse effects