title: A Bsr BI polymorphism in exon 1C of the human interleukin-1 receptor type I (IL-1RI) gene.
abstract: We have identified a single nucleotide polymorphism in the 5' region of the human interleukin-1 receptor type I (IL-1RI) gene, a C-->A transversion at position 52 in exon 1C (GenBank accession number AF172151) which creates a Bsr BI restriction endonuclease site. Allele frequencies in a Caucasian population were 0.72 (C allele) and 0.28 (A allele).
authors.affiliation: University of Bristol Department of Pathology and Microbiology, Homoeopathic Hospital Site, Cotham, Bristol BS6 6JU, UK. D.Sitara@bris.ac.uk
authors.forename: D
authors.initials: D
authors.lastname: Sitara
authors.forename: N
authors.initials: N
authors.lastname: Wood
authors.forename: H
authors.initials: H
authors.lastname: Morse
authors.forename: L
authors.initials: L
authors.lastname: Keen
authors.forename: J
authors.initials: J
authors.lastname: Bidwell
mesh_terms: D000483:Alleles; D001483:Base Sequence; D004247:DNA / Q000235:genetics; D017931:DNA Primers / Q000235:genetics; D004739:England; D005091:Exons; D005260:Female; D005787:Gene Frequency; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D012150:Polymorphism, Restriction Fragment Length; D020641:Polymorphism, Single Nucleotide; D017472:Receptors, Interleukin-1 / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid
chemical_list: D017931:DNA Primers; D017472:Receptors, Interleukin-1; D004247:DNA