title: Estimation of antithyroid antibodies occurrence in children with coeliac disease.
abstract: BACKGROUND
  The coexistence of coeliac disease (CD) and the diseases of autoimmune origin is often discussed in literature. In this study the evaluation of antithyroid antibodies (antimicrosomal-TMA, anti-thyreoglobulin-ATG, thyroid peroxidase antibodies anti-TPO) occurrence against clinical and laboratory determinants of thyroid function is demonstrated in children with coeliac disease.
  
  
  METHODS
  The study was conducted on 34 IgA-EmA positive children; control group consisted of 28 children with negative screening tests for coeliac disease.
  
  
  RESULTS
  In both groups, the level of antithyroid antibodies (TMA, ATG, anti-TPO) and determinants of thyroid gland function (TSH, fT3, fT4) were evaluated; USG examination of thyroid gland was also performed. Elevated titres of antithyroid antibodies observed in children with coeliac disease (41.1%) in comparison to control group (3.56%) indicate the need for performing the screening tests for antithyroid antibodies in children with CD.
authors.affiliation: Department of Gastroenterology and Paediatric Allergology, Institute of Paediatrics, Medical University, ul. Spoma 36/50, 91-738 Łódź, Poland.
authors.forename: E
authors.initials: E
authors.lastname: Kowalska
authors.forename: K
authors.initials: K
authors.lastname: Wasowska-Królikowska
authors.forename: E
authors.initials: E
authors.lastname: Toporowska-Kowalska
mesh_terms: D000293:Adolescent; D001323:Autoantibodies / Q000097:blood*; D016022:Case-Control Studies; D002446:Celiac Disease / Q000209:etiology / Q000276:immunology* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007453:Iodide Peroxidase / Q000276:immunology; D008861:Microsomes / Q000276:immunology; D013954:Thyroglobulin / Q000276:immunology; D013961:Thyroid Gland / Q000276:immunology* / Q000503:physiopathology
chemical_list: D001323:Autoantibodies; D013954:Thyroglobulin; D007453:Iodide Peroxidase