[Solitary fibrous thoracic wall tumor. Progression with percutaneous radiotherapy].
METHODS
A 81-year-old patient free of pain was referred to the university hospital for further evaluation and therapy of tumour masses in the right thorax. Clinical examination revealed dullness to percussion and reduced breathing in the right lower lung.


METHODS
Computed tomography showed an enlarged solid tumour mass attached to the thoracic cavity and pleural effusion on the right side. Quantification of pulmonary perfusion presented significant defects in the right upper and middle lobe.


METHODS
The pulmonary masses were biopsied under CT-guidance. Biopsy and immunohistochemical findings proved a malignant solitary fibrous tumour of the chest wall, a mesenchymal tumour of its own entity. Because of pain in the right arm and because of missing other reliable therapeutic options a palliative irradiation was performed. The tumour did increase in size due to radiotherapy and a severe right ventricular heart failure occurred. The patient died 5 months after diagnosis has been made. Autopsy revealed a transition of tumour cells to sarcomatic growth.


CONCLUSIONS
In our case we conclude an accelerated progression of the solitary fibrous chest wall tumour in the course of irradiation. Whether the development of sarcomatic growth occurred as a result of radiotherapy remains speculative.
Dietrich
C G
CG
Medizinische Klinik III, Universitätsklinikum, RWTH Aachen.
Roeb
E
E
Breuer
E
E
Matern
S
S
D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008637:Mesenchymoma / Q000473:pathology / Q000532:radiotherapy*; D010166:Palliative Care; D013899:Thoracic Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D013909:Thorax / Q000473:pathology; D014057:Tomography, X-Ray Computed
Solitärer fibröser Thoraxwandtumor. Progredienz unter perkutaner Radiatio.