Chediak-Higashi syndrome--a case report.
Chediak Higashi anomaly is a very rare disorder in which patients suffer frequent and severe pyogenic infections that are secondary to abnormal functions of polymorphonuclear leukocytes, associated with albinism and bleeding tendency. Blume RS and Wolff SM (1972) reported that only 59 cases were diagnosed after the first description of Chediak-Higashi Syndrome in 1943 by Cesar AB (cited by Wintrobe MM Clinical Haematology). As per recent literature available (Internet) last case was reported on 16th July, 1997.
Kapoor
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A
Department of Pathology MGM Medical College, Indore, MP.
Munjal
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S
Arya
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R
D000417:Albinism / Q000175:diagnosis / Q000503:physiopathology; D002609:Chediak-Higashi Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D002648:Child; D005260:Female; D006801:Humans; D009504:Neutrophils / Q000473:pathology*