Two novel diterpenoids, erinacines H and I from the mycelia of Hericium erinaceum.
Novel diterpenoids, erinacines H (1) and I (3), were isolated from the cultured mycelia of Hericium erinaceum. The structures of the compounds were determined by interpretation of the spectral data. Erinacine H showed stimulating activity of nerve growth factor (NGF)-synthesis.
Lee
E W
EW
Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University, Japan.
Shizuki
K
K
Hosokawa
S
S
Suzuki
M
M
Suganuma
H
H
Inakuma
T
T
Li
J
J
Ohnishi-Kameyama
M
M
Nagata
T
T
Furukawa
S
S
Kawagish
H
H
D000818:Animals; D001253:Astrocytes / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D001487:Basidiomycota / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D020932:Nerve Growth Factor / Q000378:metabolism; D051381:Rats; D014994:Xylose / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification*
D004224:Diterpenes; C421184:erinacine H; C421185:erinacine I; D020932:Nerve Growth Factor; D014994:Xylose