Detection of the Cryptosporidium parvum "human" genotype in a dugong (Dugong dugon).
The Cryptosporidium "human" genotype was identified in a paraffin-embedded tissue section from a dugong (Dugong dugon) by 2 independent laboratories. DNA sequencing and polymerase chain reaction/restriction fragment length polymorphism analysis of the 18S ribosomal RNA gene and the acetyl CoA synthethase gene clearly identified the genotype as that of the Cryptosporidium variant that infects humans. This is the first report of the human Cryptosporidium genotype in a nonprimate host.
Morgan
U M
UM
World Health Organization Collaborating Centre for the Molecular Epidemiology of Parasitic Infections, Murdoch University, Western Australia, Australia.
Xiao
L
L
Hill
B D
BD
O'Donoghue
P
P
Limor
J
J
Lal
A
A
Thompson
R C
RC
D000106:Acetate-CoA Ligase / Q000235:genetics; D000818:Animals; D003457:Cryptosporidiosis / Q000469:parasitology / Q000662:veterinary*; D016785:Cryptosporidium parvum / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D016054:DNA, Protozoan / Q000737:chemistry; D004275:DNA, Ribosomal / Q000737:chemistry; D020454:Dugong / Q000469:parasitology*; D005838:Genotype; D006801:Humans; D009894:Opportunistic Infections / Q000469:parasitology / Q000662:veterinary; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012150:Polymorphism, Restriction Fragment Length; D011793:Queensland; D012337:RNA, Ribosomal, 18S / Q000235:genetics; D016415:Sequence Alignment / Q000662:veterinary; D015047:Zoonoses
D016054:DNA, Protozoan; D004275:DNA, Ribosomal; D012337:RNA, Ribosomal, 18S; D000106:Acetate-CoA Ligase