Aberrant regeneration of the third nerve.
We describe three patients with aberrant regeneration of the third nerve secondary to traumatic brain injury. The full blown features of the syndrome include horizontal gaze-eyelid synkinesis, pseudo-Graefe sign, limitation of elevation and depression of the eye with retraction of the globe on attempted vertical movements, adduction of the involved eye on attempted elevation or depression, pseudo-Argyll Robertson pupil and absent vertical optokinetic response. The 'misdirection' incidence in our study is 15%.
Chua
H C
HC
Department of Neurology, National Neuroscience Institute, 11, Jalan Tan Tock Seng, Singapore 308433. hoe_chin_chua@notes.ttsh.gov.sg
Tan
C B
CB
Tjia
H
H
D000328:Adult; D001930:Brain Injuries / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015835:Ocular Motility Disorders / Q000209:etiology; D009802:Oculomotor Nerve / Q000254:growth & development* / Q000473:pathology; D015840:Oculomotor Nerve Diseases / Q000209:etiology / Q000473:pathology*; D011247:Pregnancy; D011681:Pupil Disorders / Q000209:etiology / Q000473:pathology