title: [Usefulness of Dermatophagoides pteronyssinus allergen extract from the Allergopharma J.G. Company for bronchial provocation in patients with bronchial asthma].
abstract: The value of Dpt allergen extract, produced by Allergopharma J.G., for performance of the bronchial provocation test in asthmatics was evaluated. The studies were carried out in 40 asthmatics with positive skin prick test with Dpt. Bronchial provocation test was performed according to Ryan's method. After an allergen inhalation, an early asthmatic reaction (EAR) and late asthmatic reaction (LAR) may appear. The following results were observed: a dual asthmatic reaction (EAR and LAR)--in 19 persons, the EAR--only in 9 patients, and the LAR--only in 1 patient. The negative result of the provocation were found in 11 patients. The frequency of particular patterns of the bronchial reactions was similar to those published before by us and other authors, with different allergen extracts. The allergen extract of Dpt from Allergopharma J.G. can be used to bronchial challenge.
authors.affiliation: Kliniki Alergologii i Chorób Wewnetrznych Akademii Medycznej w Białymstoku.
authors.forename: Z
authors.initials: Z
authors.lastname: Siergiejko
authors.forename: Z
authors.initials: Z
authors.lastname: Zietkowski
authors.forename: A
authors.initials: A
authors.lastname: Tomorowicz
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000941:Antigens / Q000276:immunology; D039741:Antigens, Dermatophagoides; D001249:Asthma / Q000209:etiology*; D001985:Bronchial Provocation Tests; D004391:Dust / Q000009:adverse effects; D005260:Female; D006023:Glycoproteins / Q000276:immunology; D006801:Humans; D008297:Male; D008925:Mites / Q000276:immunology*; D012129:Respiratory Function Tests; D012130:Respiratory Hypersensitivity / Q000150:complications* / Q000175:diagnosis*; D012882:Skin Tests
chemical_list: D000941:Antigens; D039741:Antigens, Dermatophagoides; D004391:Dust; D006023:Glycoproteins
vernacular_title: Ocena przydatności wyciagu alergenowego Dermatophagoides pteronyssinus firmy Allergopharma J.G. do przeprowadzania swoistych, prowokacyjnych testów oskrzelowych u chorych na astme oskrzelowa.