Alternate exon in the 5'-untranslated region of the human ACTH receptor gene.
The human ACTH receptor (ACTH-R) gene consists of two exons; the first encodes the 5'-untranslated region (UTR) and the second encodes part of the 5'-UTR, the entire coding region, and the whole of the 3'-UTR. While investigating the transcription initiation site of the human ACTH-R gene by 5'-rapid amplification of cDNA ends, we found a 157-bp alternate exon in the 5'-UTR. This newly identified exon was irrelevant to the alternate exon in the mouse ACTH-R gene which we reported previously.
Kubo
M
M
Health Administration Center, Hokkaido University of Education, Sapporo, Japan.
Shimizu
C
C
Kijima
H
H
Ishizuka
T
T
Takano
K
K
Takano
A
A
Koike
T
T
D020121:5' Untranslated Regions; D017398:Alternative Splicing; D001483:Base Sequence; D004587:Electrophoresis, Agar Gel; D005091:Exons; D006801:Humans; D008969:Molecular Sequence Data; D021141:Nucleic Acid Amplification Techniques; D016133:Polymerase Chain Reaction / Q000379:methods; D018043:Receptors, Corticotropin / Q000235:genetics*
D020121:5' Untranslated Regions; D018043:Receptors, Corticotropin