Comparison of immunotoxins bearing a single saporin molecule with multiple toxin conjugates.
Flavell
D J
DJ
Division of Cancer Sciences, Simon Flavell Leukemia Research Laboratory, University of Southampton, Southampton General Hospital, Hampshire, UK.
Flavell
S U
SU
D000818:Animals; D002852:Chromatography, Ion Exchange; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007074:Immunoglobulin G / Q000737:chemistry / Q000494:pharmacology; D000922:Immunotoxins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use; D008223:Lymphoma / Q000188:drug therapy; D051379:Mice; D016513:Mice, SCID; D009699:N-Glycosyl Hydrolases; D010940:Plant Proteins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use; D014176:Protein Biosynthesis / Q000187:drug effects; D054789:Ribosome Inactivating Proteins, Type 1; D012270:Ribosomes / Q000187:drug effects*; D000076985:Saporins; D023041:Xenograft Model Antitumor Assays
D007074:Immunoglobulin G; D000922:Immunotoxins; D010940:Plant Proteins; D054789:Ribosome Inactivating Proteins, Type 1; D009699:N-Glycosyl Hydrolases; D000076985:Saporins; C024275:pokeweed antiviral protein