title: Endonucleases.
abstract: Programmed cell death (PCD) involves hydrolysis of genomic DNA, which must be catalyzed by endonuclease(s) capable of digesting dsDNA. Plants have two major classes of endonucleases active towards dsDNA, Zn2+-dependent endonuclease and Ca2+-dependent endonuclease. Both classes are found among endonucleases nominated for machineries of PCD in plants. Survey of plant endonucleases in relation to PCD leads to a possibility that a different class of endonuclease reflects a different phase of PCD-associated DNA hydrolysis.
authors.affiliation: Botanical Gardens, Graduate School of Science, Tle University of Tokyo, Japan. sugiyama@ns.bg.s.u-tokyo.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Sugiyama
authors.forename: J
authors.initials: J
authors.lastname: Ito
authors.forename: S
authors.initials: S
authors.lastname: Aoyagi
authors.forename: H
authors.initials: H
authors.lastname: Fukuda
mesh_terms: D000595:Amino Acid Sequence; D017209:Apoptosis; D018744:DNA, Plant / Q000235:genetics / Q000378:metabolism*; D004720:Endonucleases / Q000378:metabolism*; D008969:Molecular Sequence Data; D059828:Plant Cells; D010944:Plants / Q000201:enzymology / Q000235:genetics; D017386:Sequence Homology, Amino Acid
chemical_list: D018744:DNA, Plant; D004720:Endonucleases