Idiopathic thrombocytopenic purpura and MMR vaccine.
A CAUSAL ASSOCIATION BETWEEN MEASLES: mumps-rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP) was confirmed using immunisation/hospital admission record linkage. The absolute risk within six weeks of immunisation was 1 in 22 300 doses, with two of every three cases occurring in the six week post-immunisation period being caused by MMR. Children with ITP before MMR had no vaccine associated recurrences.
Miller
E
E
Immunisation Division, Public Health Laboratory Service Communicable Disease Surveillance Centre, Colindale, London NW9 5EQ, UK. e.miller@phls.co.uk
Waight
P
P
Farrington
C P
CP
Andrews
N
N
Stowe
J
J
Taylor
B
B
D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D022542:Measles-Mumps-Rubella Vaccine / Q000009:adverse effects*; D008498:Medical Record Linkage; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D006113:United Kingdom / Q000453:epidemiology
D022542:Measles-Mumps-Rubella Vaccine