[Differential diagnosis of oxyphilic (Hürthle cell) adenomas and carcinomas of the thyroid].
Successful application of a double immunostaining of oxyphilic tumors with a specific antimitochondrial antibody and proliferative marker Ki-67 was made for the first time. Comparative study of proliferative activity did not show a statistically significant difference between Hurthle-cell adenomas and carcinomas. However, oxyphilic carcinomas had a statistically significant positive correlation between proliferative index and aggressive course of tumor, tendency to recurrence, high metastatic activity, tumor size, presence of necrosis and capsule penetration.
Tret'iakova
M S
MS
Medical Academy of Advanced Medical Education, 194356, St-Petersburg.
Bussolati
J
J
D000230:Adenocarcinoma / Q000473:pathology*; D018249:Adenoma, Oxyphilic / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D013964:Thyroid Neoplasms / Q000473:pathology*
I differentsial'noĭ diagnostike oksifil'nykh (Giurtle-kletochnykh) adenom i kartsinom shchitovidnoĭ zhelezy.