title: A multiple focused probe approach for high intensity focused ultrasound based surgery.
abstract: To produce deep-seated surgical lesions using ultrasound requires high power and intensity levels at the target sites. Conventionally, large transducers are used which require big apertures and so are generally suitable only for extra-corporeal access. Such transducers also result in strong off-focus maxima, where the resulting hot spots can destroy normal tissue whilst deep-seated large tissue volumes are being ablated. This paper describes a new approach in which it is proposed that multiple probes are used simultaneously, each at a relatively low power, to result in an overlapping focused region of high temperature without strong off-focus hot spots. Robotic techniques could be used to move the individual probes in coordination to sweep out the desired region of tissue ablation. Simulation and planning are the key to quality prediction for high intensity focused ultrasound (HIFU). Simplified two-dimensional and three-dimensional models of HIFU probes have been developed to study the characteristics of various multi-probe configurations. Preliminary simulation results show that the multi-probe system can be arranged successfully to minimise off-focus hot spots. Experimental results are presented which validate the modality and confirm this positive finding. Further prediction studies and planning will be necessary to achieve the most appropriate desired treatment, by varying the pulse duration and spacing.
authors.affiliation: Department of Mechanical Engineering, Imperial College of Science, Technology and Medicine, London, UK.
authors.forename: S
authors.initials: S
authors.lastname: Chauhan
authors.forename: M J
authors.initials: MJ
authors.lastname: Lowe
authors.forename: B L
authors.initials: BL
authors.lastname: Davies
mesh_terms: D003198:Computer Simulation; D004867:Equipment Design; D006801:Humans; D009369:Neoplasms / Q000601:surgery*; D012371:Robotics / Q000295:instrumentation; D014159:Transducers; D014464:Ultrasonic Therapy / Q000295:instrumentation*