The absorption of protein hormones through rabbit rhinal mucosa.
The absorptions through rabbit rhinal mucosa of the following hormones with a protein-peptide structure: thyrotropin-releasing hormone, insulin, and prolactin, were compared. A very high negative correlation between the molecular weight of the hormones and the total amount of the hormones molecular weight of hormones absorbed through the rhinal mucosa (r = 0.973) was found. Within 2 hours of the experiment, 33.94% TRH, 23.96% INS, and only 11.01% PRL, were absorbed from the administered dose.
Dolinska
B
B
Department of Applied Pharmacy and Drug Technology Silesian Medical Academy ul. Kasztanowa 3, 41-205 Sosnowiec, Poland.
Ryszka
F
F
Suszka-Switekz
A
A
D000818:Animals; D006728:Hormones / Q000097:blood / Q000493:pharmacokinetics*; D066298:In Vitro Techniques; D009297:Nasal Mucosa / Q000378:metabolism*; D010455:Peptides / Q000097:blood / Q000493:pharmacokinetics; D011817:Rabbits
D006728:Hormones; D010455:Peptides