[STR polymorphisms in five Chinese ethnic groups(2)].
Population genetic studies were performed in Chinese Han, Hui, Mongolian, Tibetan and Uygur. Allele frequency distributions were analyzed for ten loci, i.e., D3S1358, VWA, CSF1PO, FGA, THO1, TPOX, D5S818, D13S317 and D7S820 by GeneScan. The results showed that there were 60 STR alleles and 149 genotypes in Han; 63 STR alleles and 144 genotypes in Hui; 69 STR alleles and 173 genotypes in Mongolian; 77 STR alleles and 168 genotypes in Tibetan; 70 STR alleles and 148 genotypes in Uygur. Significant differences were identified among ethnic groups (African-American, US-Caucasian and Chinese-Oriental), but similarity was found among the five Chinese populations, and immunogenomics and pharmacogenomics studied in this report. These findings indicated that the nine STR loci and amelogenin locus were very useful for individual identification in forensic science.
Li
S B
SB
Human Genome Center, Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China. shbinlee@hotmail.com
Lai
J H
JH
Gao
S H
SH
Zheng
H B
HB
Feng
J D
JD
Zhao
J M
JM
Li
S D
SD
Feng
C B
CB
Jin
T B
TB
Wang
J
J
Yang
H M
HM
D000483:Alleles; D044466:Asian People / Q000235:genetics*; D002681:China / Q000208:ethnology; D002874:Chromosome Mapping; D006801:Humans; D011110:Polymorphism, Genetic; D020080:Tandem Repeat Sequences