[Preparation of pellets with a centrifugal granulator].
It has been investigated how the centrifugal-granulator is applicable to form paracetamol pellets with good mechanical, powder rheological and dissolutional properties. During the preparation process the mechanical parameters were the same only the percentage of the effective material was changed. The authors found that the centrifugal-granulator is well applicable to form good pellet particles which have good dissolution and mechanical parameters to from needle shaped raw materials.
Kása
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Szegedi Tudományegyetem, Gyógyszertechnológiai Intézet, 6720 Szeged, Eötvös u. 6.
Hódi
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K
Révész
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P
Erós
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I
D002498:Centrifugation; D004343:Drug Implants; D012212:Rheology; D012995:Solubility
D004343:Drug Implants
Pelletek elöállítása centrifugál-granulátorban.