Antioxidant activity of soya hypocotyl tea in humans.
Antioxidative activity of isoflavones has not been shown in humans. Newly-developed isoflavone-rich soya hypocotyl tea contains about 12 mg isoflavones per liter. 15 tea drinkers and 23 control young female students were randomly selected from volunteers, and underwent physical examination, blood chemistry and urinary analysis before and after one month of tea drinking. A three-day dietary record was taken before each physical examination. The tea drinkers showed a lower level of phosphatidylcholine hydroperoxide (PCOOH) and phosphatidyl-ethanolamine hydroperoxide (PEOOH) in the red blood cells and a significant reduction of 8-hydroxydeoxyguanine (8ohdG) in the urine compared to the controls.
Watanabe
S
S
Department of Nutritional Science, Faculty of Applied Bioscience, Tokyo University of Agriculture, Japan. swatanab@nodai.ac.jp
Haba
R
R
Terashima
K
K
Arai
Y
Y
Miura
T
T
Chiba
H
H
Takamatsu
K
K
D000080242:8-Hydroxy-2'-Deoxyguanosine / Q000031:analogs & derivatives; D000975:Antioxidants / Q000008:administration & dosage*; D002784:Cholesterol / Q000097:blood; D004032:Diet; D004912:Erythrocytes / Q000737:chemistry; D005260:Female; D006147:Guanine / Q000031:analogs & derivatives* / Q000652:urine; D006801:Humans; D018546:Hypocotyl; D007529:Isoflavones / Q000008:administration & dosage* / Q000652:urine; D010713:Phosphatidylcholines / Q000097:blood; D010714:Phosphatidylethanolamines / Q000097:blood; D012709:Serum Albumin / Q000032:analysis; D013025:Glycine max; D013662:Tea; D014280:Triglycerides / Q000097:blood; D014815:Vitamins / Q000097:blood
D000975:Antioxidants; D007529:Isoflavones; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D012709:Serum Albumin; D013662:Tea; D014280:Triglycerides; D014815:Vitamins; C057590:phosphatidylcholine hydroperoxide; C027850:phosphatidylethanolamine hydroperoxide; D006147:Guanine; C004742:daidzein; C078307:8-oxo-7,8-dihydrodeoxyguanine; D000080242:8-Hydroxy-2'-Deoxyguanosine; D002784:Cholesterol