title: [Diagnosis of hemochromatosis with magnetic resonance].
abstract: Hemochromatosis is a disorder of parenchymal iron overload. The diagnosis is based upon clinical manifestations, laboratory findings and iron concentration in liver. Magnetic resonance imaging (MRI) shows a decrease in liver signal intensity. Its role has not been already defined. Nonetheless, ratio of liver to muscle proton density (LMPD) shows a significant correlation with hepatic iron. One patient with a long-standing cirrhosis with data of hemochromatosis whose coagulation study did not allow to perform a liver biopsy was diagnosed with this method. Hepatic iron concentration was calculated based upon: microgram/g of hepatic iron = (-5.174* LMPD) + 9.932. MRI can be useful in the evaluation of hemochromatosis among patients who refuse or have contraindication to liver biopsy.
authors.affiliation: Servicio de Aparato Digestivo, Hospital Universitario Clínico San Carlos, Universidad Complutense, Madrid.
authors.forename: J R
authors.initials: JR
authors.lastname: Larrubia
authors.forename: J L
authors.initials: JL
authors.lastname: Mendoza
authors.forename: J A
authors.initials: JA
authors.lastname: Pérez de la Serna
authors.forename: A
authors.initials: A
authors.lastname: Ruiz de León
authors.forename: R
authors.initials: R
authors.lastname: Méndez
authors.forename: M
authors.initials: M
authors.lastname: Díaz-Rubio
mesh_terms: D000368:Aged; D006432:Hemochromatosis / Q000175:diagnosis*; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male
vernacular_title: Diagnóstico de la hemocromatosis por resonancia magnética.