Sesquiterpenes from the leaves of Ligularia fischeri var. spiciformis.
From the leaves of Ligularia fischeri var. spiciformis, a new eremophilanolide, 8 alpha-methoxy-6-oxoeremophil-7(11)-en-12,8-olide (6-oxoeremophilenolide) and a eudesmane-type sesquiterpene, (+)-intermedeol were isolated. The structures were determined on the basis of 2D-NMR spectral data. Data on cytotoxicity showed that the latter was clearly more potent than the former compound.
Park
H J
HJ
Kwon
S H
SH
Yoo
K O
KO
Sohn
I C
IC
Lee
K T
KT
Lee
H K
HK
D019659:Asteraceae / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013057:Spectrum Analysis; D014407:Tumor Cells, Cultured
D012717:Sesquiterpenes