title: Effects of prosthetic valve placement on mitral annular dynamics and the left ventricular base.
abstract: Insertion of a rigid mitral prosthesis impairs the function of the mitral annulus and induces systolic narrowing of the left ventricular outflow tract (LVOT). To study this mechanism, we investigated dynamic changes in the left ventricular (LV) base, which consists of the mitral annulus and LVOT orifice. In seven patients with mechanical mitral valve prostheses and eight normal subjects, the image of the LV base was reconstructed three-dimensionally and its dynamic change during systole was studied. In the patients, the rigid prosthetic valve (=mitral annulus) tilted toward the left ventricle with a hinge point at the posterior mitral annulus during systole. The left ventricular base exhibited contraction, but the size of the prosthetic valve was constant. As a consequence, the prosthetic valve occupied more of the left ventricular base, which resulted in narrowing of the LVOT. In the normal subjects, the mitral annulus did not interfere with the region of the LVOT orifice during systole as the mitral annulus underwent both dorsiflexion and contraction. Thus, fixation of the mitral annulus induces an anti-physiologic motion of the annulus. Conscious preservation of annular flexibility in mitral valve surgery is important in avoiding potential dynamic LVOT obstruction.
authors.affiliation: Department of Cardiovascular Surgery, German Heart Institute Berlin.
authors.forename: T
authors.initials: T
authors.lastname: Komoda
authors.forename: R
authors.initials: R
authors.lastname: Hetzer
authors.forename: H
authors.initials: H
authors.lastname: Siniawski
authors.forename: J
authors.initials: J
authors.lastname: Oellinger
authors.forename: R
authors.initials: R
authors.lastname: Felix
authors.forename: C
authors.initials: C
authors.lastname: Uyama
authors.forename: H
authors.initials: H
authors.lastname: Maeta
mesh_terms: D000328:Adult; D000368:Aged; D004452:Echocardiography; D006350:Heart Valve Prosthesis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008422:Materials Testing; D008875:Middle Aged; D008943:Mitral Valve / Q000502:physiology*; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery*; D012016:Reference Values; D013318:Stroke Volume; D013599:Systole; D016277:Ventricular Function, Left