Upper airways locations of plasmocytoma.
We report one case of extramedullary plasmocytoma located in the nasopharynx. After 8 years, the tumor recurred in the same location and 3 years later, the patient develop a multiple myeloma. Three clinical and pathological entities of plasmocytoma are described: multiple myeloma, solitary bone plasmocytoma and extramedullary plasmocytoma. When histological examination show plasmocytoma, further examinations can or not reveal a multiple myeloma. In 80% of cases, extramedullary plasmocytoma occur in the upper respiratory tract. This development of multiple myeloma from extramedullary plasmocytoma is seen in 5 to 32% of patients and sometimes an extremely long time is required for the change to occur. The treatments are surgery and radiation in the absence of generalized disease.
Courtmans
I
I
Service ORL, Clinique Saint-Pierre, avenue Reine Fabiola 9, Ottignies.
Pigeolet
Y
Y
Hedayat
A H
AH
Vilain
J
J
D000368:Aged; D001706:Biopsy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009101:Multiple Myeloma / Q000175:diagnosis / Q000473:pathology; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D009305:Nasopharynx / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology; D010954:Plasmacytoma / Q000175:diagnosis* / Q000473:pathology