title: [Combined effects caused by chronic exposure to vinyl chloride and dichloroethane].
abstract: The authors studied solitary and combined effects of vinyl chloride and dichloroethane in chronic (4 months) inhalation experiment using concentrations of 50 and 500 mg/m3. The experiment revealed general toxic effects including disorders of central nervous system and liver. Those disorders are caused by reductive-oxidative reactions disturbances and dystrophic processes. The authors determined safe combinations of vinyl chloride and dichloroethane concentrations for associated action.
authors.forename: M F
authors.initials: MF
authors.lastname: Savchenkov
authors.forename: E P
authors.initials: EP
authors.lastname: Lemeshevskaia
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Katul'skiĭ
authors.forename: V V
authors.initials: VV
authors.lastname: Benemanskiĭ
authors.forename: E V
authors.initials: EV
authors.lastname: Zhukova
authors.forename: I G
authors.initials: IG
authors.lastname: Pogorelova
authors.forename: L I
authors.initials: LI
authors.lastname: Syrosenko
authors.forename: I P
authors.initials: IP
authors.lastname: Pankratov
mesh_terms: D000818:Animals; D001933:Brain Stem / Q000378:metabolism; D005018:Ethyl Chloride / Q000493:pharmacokinetics / Q000633:toxicity*; D008099:Liver / Q000378:metabolism; D008297:Male; D051381:Rats; D013997:Time Factors; D014752:Vinyl Chloride / Q000493:pharmacokinetics / Q000633:toxicity*
chemical_list: D005018:Ethyl Chloride; D014752:Vinyl Chloride
vernacular_title: Kombinirovannoe deĭstvie vinilkhlorida i dikhlorétana pri dlinel'nov postuplenii v ornanizm.