title: The homocamptothecin, BN 80927, is a potent topoisomerase I poison and topoisomerase II catalytic inhibitor.
authors.affiliation: Institut Henri Beaufour, 5 avenue du Canada, 91966 Les Ulis, France. daniele.demarquay@beaufour-ipsen.com
authors.forename: D
authors.initials: D
authors.lastname: Demarquay
authors.forename: H
authors.initials: H
authors.lastname: Coulomb
authors.forename: M
authors.initials: M
authors.lastname: Huchet
authors.forename: L
authors.initials: L
authors.lastname: Lesueur-Ginot
authors.forename: J
authors.initials: J
authors.lastname: Camara
authors.forename: O
authors.initials: O
authors.lastname: Lavergne
authors.forename: D
authors.initials: D
authors.lastname: Bigg
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D002166:Camptothecin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D002384:Catalysis / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005047:Etoposide / Q000494:pharmacology; D006801:Humans; D000077146:Irinotecan; D019384:Nucleic Acid Synthesis Inhibitors / Q000494:pharmacology; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors
chemical_list: D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; C121907:BN 80927; D004791:Enzyme Inhibitors; D019384:Nucleic Acid Synthesis Inhibitors; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; D005047:Etoposide; D000077146:Irinotecan; D002166:Camptothecin