ChromWin--a computer program for the determination of enantiomerization barriers in dynamic chromatography.
The software program ChromWin simulates interconversion profiles in dynamic chromatography (rearrangements, isomerizations, epimerizations, diastereomerizations and, notably, enanatiomerizations) on a personal computer in a user-friendly environment. ChromWin is especially suited for systems involving large plate numbers, e.g. gas chromatography (GC) and capillary electrophoresis (CE, CEC, MEKC), and first or pseudo-first order reactions. ChromWin (1) simulates the elution profiles of interconverting enantiomers by different models and yields the rate constant, (2) allows automation of the 'find enantiomerization barrier' function, (3) helps to optimise separation parameters by visualization of the separation process and (4) provides other useful tools for chromatography. In addition to the theoretical plate and the stochastic model a modified and improved stochastic model has been developed and implemented in the program.
Trapp
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O
Institute of Organic Chemistry, University of Tübingen, Germany. oliver.trapp@uni-tuebingen.de
Schurig
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