title: Synthesizing oligomers from monomeric nucleotides in simulated hydrothermal environments.
abstract: Dimers and trimers of adenosine monophosphate (AMP) were synthesized from AMP in environments simulating hot vents on the sea floor of the primitive Earth. The simulated environments were made in the flow reactor, in which an aqueous solution of reactants was circulated from the hot to the cold region repeatedly. The oligomerization proceeded most significantly when the hot reaction solution at about 110 degrees C was abruptly ejected into the cold environment maintained at about 0 degree C.
authors.affiliation: Department of BioEngineering, Nagaoka University of Technology, Nagaoka 940-2188, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ogasawara
authors.forename: A
authors.initials: A
authors.lastname: Yoshida
authors.forename: E
authors.initials: E
authors.lastname: Imai
authors.forename: H
authors.initials: H
authors.lastname: Honda
authors.forename: K
authors.initials: K
authors.lastname: Hatori
authors.forename: K
authors.initials: K
authors.lastname: Matsuno
mesh_terms: D000227:Adenine Nucleotides / Q000138:chemical synthesis / Q000737:chemistry*; D000249:Adenosine Monophosphate / Q000737:chemistry*; D002712:Chlorides; D019281:Dimerization; D018534:Earth, Planet; D019418:Evolution, Chemical; D006358:Hot Temperature; D009843:Oligoribonucleotides / Q000138:chemical synthesis / Q000737:chemistry*; D000069497:Origin of Life; D014867:Water; D017967:Zinc Compounds
chemical_list: D000227:Adenine Nucleotides; D002712:Chlorides; D009843:Oligoribonucleotides; D017967:Zinc Compounds; D014867:Water; D000249:Adenosine Monophosphate; C023505:2',5'-oligoadenylate; C016837:zinc chloride