[Change in Ca2+ transport in myometrial plasma cell membrane in proton gradient dissipation].
By means of delta pH 14C-methylamine indicator the myometrium vesicle sarcolemma fraction was shown to be capable, while applying a "delta pH-leap", for developing in it a proton transmembrane gradient, dissipating in time. The proton gradient dissipation under Ca ions transmembrane equilibrium concentration is a driving force of these ions transposition against the concentration gradient. The blocking agents of H+ transport--Cd ions and DCCD decrease the proton-dependent 45Ca2+ accumulation in the vesicle sarcolemma fraction. The conclusion has been made about the possibility of Ca2+(H(+)-exchange on the uterus smooth cells sarcolemma. The possible physiological value of this exchange is under discussion.
Tuhaĭ
V A
VA
O.V. Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv.
Danylovych
Iu V
IuV
D000818:Animals; D002104:Cadmium / Q000378:metabolism; D002118:Calcium / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D005260:Female; D006863:Hydrogen-Ion Concentration; D017136:Ion Transport; D009215:Myometrium / Q000378:metabolism*; D011522:Protons; D013552:Swine
D011522:Protons; D002104:Cadmium; D002118:Calcium
Zminy transportu Ca2+ u plazmatychniĭ membrani klityn miometriia v umovakh rozspovannia hradiienta protoniv.