Evaluation of chicken infectious anemia virus and associated risk factors with disease and production losses in broilers.
A case-control study was performed to determine the significance of chicken infectious anemia virus (CIAV) as a risk factor associated with secondary disease in commercial broilers and to identify the significance of production losses associated with CIAV. The study also examined the relationship between bursal and thymic atrophy and the presence of CIAV. Cases were defined as submissions to the Alabama Veterinary Diagnostic Laboratories with a history of clinical disease and with a diagnosis of coccidiosis, gangrenous dermatitis, or respiratory disease. Controls were selected from submissions with neither a history of disease nor evidence of disease on necropsy. CIAV was detected in fresh tissues by polymerase chain reaction. Both thymic atrophy and the detection of CIAV were significantly associated with a disease case (P < 0.05). Bursal atrophy was a significant risk factor associated with the detection of CIAV in a submission (P < 0.05). Whereas CIAV was associated with disease cases that showed production losses in both percentage of livability and percentage of condemnations (P < 0.05), detection of CIAV alone was not associated with detectable losses in production or flock performance.
Hagood
L T
LT
Charles S. Roberts Veterinary Diagnostic Laboratory, Auburn, AL 36831-2209, USA.
Kelly
T F
TF
Wright
J C
JC
Hoerr
F J
FJ
D000383:Agriculture; D000818:Animals; D001284:Atrophy; D002060:Bursa of Fabricius / Q000473:pathology; D016022:Case-Control Studies; D017727:Chicken anemia virus / Q000502:physiology*; D002645:Chickens; D018173:Circoviridae Infections / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D011201:Poultry Diseases / Q000175:diagnosis / Q000473:pathology / Q000821:virology*; D012189:Retrospective Studies; D012307:Risk Factors; D013950:Thymus Gland / Q000473:pathology