title: [Meningeal carcinomatosis as first manifestation of carcinoma of the bladder: report of 2 cases].
abstract: Meningeal carcinomatosis may occur in 0.8-8% of patients with solid tumors. The most common tumors associated with that condition are breast and small cell lung cancer. Meningeal carcinomatosis from urothelial cancer is rare, and it appears described in advanced stages of disease, generally, after chemotherapy. Two cases of meningeal carcinomatosis as the first manifestation of bladder cancer were reported. In the first case, a 46-year-old man presented signs and symptoms indicative of involvement of the spinal roots, subsequently neurologic dysfunction of the brain and cranial nerves appeared. In the second case, a 68-year-old man was admitted to our hospital with a history compatible with panhypopituitarism and pulmonary lymphangitic carcinomatosis from cancer of unknown primary site. Follow-up revealed a transitional cell carcinoma of the bladder and hydrocephalus due to cerebrospinal fluid outflow obstruction. We emphasize in the polymorphic presentation of meningeal carcinomatosis and the necessity to consider the bladder as primary tumor localization.
authors.affiliation: Unidad de Oncología Médica, Hospital de Sagunt, Valencia.
authors.forename: O
authors.initials: O
authors.lastname: Juan Vidal
authors.forename: L
authors.initials: L
authors.lastname: de Paz Arias
authors.forename: J
authors.initials: J
authors.lastname: Catalá Barceló
authors.forename: M
authors.initials: M
authors.lastname: García Escrig
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary*; D002295:Carcinoma, Transitional Cell / Q000556:secondary*; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000556:secondary*; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000473:pathology*
vernacular_title: Carcinomatosis meníngea como primera manifestación del carcinoma de vejiga: a propósito de dos casos.