title: Lupus-like syndrome with submassive hepatic necrosis associated with hepatitis A.
abstract: Hepatitis A is a common self-limited liver disease. However, 15% of patients may have some complications. Autoimmune hepatitis that is triggered by viral hepatitis has been reported. We hereby describe an unrecognized association of hepatitis A with a full blown lupus-like syndrome manifested by the appearance of arthralgia, exudative pleural effusion with the presence of lupus erythematosus cells and autoantibodies. All these findings disappeared after a short course of steroid treatment. The case is presented and the literature is reviewed.
authors.affiliation: Department of Internal Medicine B, Meir Hospital, Kfar-Saba, Israel. amitse@inter.net.il
authors.forename: A
authors.initials: A
authors.lastname: Segev
authors.forename: R
authors.initials: R
authors.lastname: Hadari
authors.forename: T
authors.initials: T
authors.lastname: Zehavi
authors.forename: M
authors.initials: M
authors.lastname: Schneider
authors.forename: R
authors.initials: R
authors.lastname: Hershkoviz
authors.forename: Y A
authors.initials: YA
authors.lastname: Mekori
mesh_terms: D000208:Acute Disease; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006506:Hepatitis A / Q000150:complications* / Q000473:pathology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010996:Pleural Effusion / Q000209:etiology; D011241:Prednisone / Q000627:therapeutic use; D013577:Syndrome
chemical_list: D000893:Anti-Inflammatory Agents; D011241:Prednisone