Carbamazepine hypersensitivity syndrome mimicking mycosis fungoides.
We report a case of a patient who experienced a generalized skin rash with systemic involvement 2 months after beginning carbamazepine treatment for trigeminal neuralgia. Skin biopsy specimens suggest mycosis fungoides. Complete remission of the clinical and pathologic changes after drug discontinuation and the positive result of carbamazepine from an epicutaneous test suggest a diagnosis of pseudolymphoma due to carbamazepine.
Miranda-Romero
A
A
Departamento de Dermatologia, Hospital Universitario de Valladolid, Calle Ramón y Cajal s/n, 47005, Valladolid, Spain.
Pérez-Oliva
N
N
Aragoneses
H
H
Bastida
J
J
Raya
C
C
González-Lopez
A
A
García-Muñoz
M
M
D000368:Aged; D000927:Anticonvulsants / Q000009:adverse effects*; D002220:Carbamazepine / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D009182:Mycosis Fungoides / Q000175:diagnosis* / Q000209:etiology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000209:etiology; D013577:Syndrome
D000927:Anticonvulsants; D002220:Carbamazepine