Syntheses of the L-manno and some other analogs of the terminal determinants of the O-PS of Vibrio cholerae O:1.
Analogs of the methyl alpha-glycosides of the terminal residues of the O-specific polysaccharides (O-PS) of Vibrio cholerae O:1, serotype Inaba and Ogawa, have been prepared as probes to study their interaction with anti V. cholerae O:1 antibodies. They differ from the termini of the respective O-PSs in anomeric or absolute configuration of perosamine, position of the O-methyl group in D-perosamine, and nature of the N-acyl side chain.
Poirot
E
E
National Institutes of Health, Bethesda, MD 20892-0815, USA.
Zhang
X
X
Whittaker
N F
NF
Kovác
P
P
D000942:Antigens, Bacterial / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D000939:Epitopes / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry; D008358:Mannose / Q000031:analogs & derivatives* / Q000737:chemistry; D018716:Molecular Mimicry; D019081:O Antigens / Q000737:chemistry* / Q000276:immunology; D014734:Vibrio cholerae / Q000276:immunology*
D000942:Antigens, Bacterial; D000939:Epitopes; D006027:Glycosides; D019081:O Antigens; C057033:4-amino-4,6-dideoxy-D-mannose; D008358:Mannose