title: Breast cancer in pregnancy--our experience with six patients in the University Hospital, Kuala Lumpur.
abstract: Presentation of breast cancer during pregnancy is a rare situation and one that requires a multidisciplinary approach involving an obstetrician, surgeon and oncologist. Management should be along the same principles as in non-pregnant patients and delay is not justifiable. Mastectomy and axillary clearance is the best option, followed by chemotherapy, which is safe after the first trimester. Radiation if required should be delayed until after delivery of the baby. We present here our experience with 6 patients who presented with breast cancer during pregnancy. Five patients refused any treatment until after delivery, while one underwent only a mastectomy and axillary clearance. The outcome was poor; all of them died between 14 months and 52 months. The poor outcome probably reflects the late stage at presentation in four of the patients (State 3 and 4) rather than the delay in treatment, while delay in treatment in the two who presented with early cancer (Stage 1 and 2) led to a more advanced stage after delivery.
authors.affiliation: Department of Surgery, University Hospital, 50603 Kuala Lumpur.
authors.forename: C H
authors.initials: CH
authors.lastname: Yip
authors.forename: N A
authors.initials: NA
authors.lastname: Taib
authors.forename: M M
authors.initials: MM
authors.lastname: Abdullah
authors.forename: I
authors.initials: I
authors.lastname: Wahid
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006785:Hospitals, University; D006801:Humans; D008197:Lymph Node Excision; D008296:Malaysia; D008408:Mastectomy; D008875:Middle Aged; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*