title: [The use of biological preparations for correction of microbial status in pregnant women].
abstract: 15 pregnant women with pregnancy lasting 28-32 weeks, whose medico-laboratory data (the positive result of the amino test, high pH value and the detection of "key" cells) suggested the presence of bacterial vaginosis, were placed under observation. The bacteriological study of vaginal microflora in all these women revealed pronounced disturbances simultaneously with the development of intestinal dysbacteriosis. The local application of the bacterial preparation "Zhlemik" containing freeze-dried live lactic acid bacteria of vaginal origin and the oral administration of lactic acid bifidumbacterin containing live bifidobacteria of intestinal origin permitted the successful restoration of vaginal and intestinal microbiocenosis. The capacity of biotherapeutic preparations for inducing non-specific immunostimulation led to a significant rise in the levels of IgA, IgM and IgG in vaginal secretions.
authors.affiliation: Russian State Medical University, Institute of Medico-Social Rehabilitation, Research Institute of Immunology, Moscow, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Korshunova
authors.forename: L I
authors.initials: LI
authors.lastname: Kafarskaia
authors.forename: B A
authors.initials: BA
authors.lastname: Efimov
authors.forename: O V
authors.initials: OV
authors.lastname: Makarov
authors.forename: B V
authors.initials: BV
authors.lastname: Pinegin
authors.forename: V M
authors.initials: VM
authors.lastname: Korshunov
mesh_terms: D001430:Bacteriocins / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D007778:Lactobacillus; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D014621:Vagina / Q000382:microbiology*; D016585:Vaginosis, Bacterial / Q000188:drug therapy*
chemical_list: D001430:Bacteriocins; C066526:zhlemik
vernacular_title: Primenenie bioterapevticheskikh preparatov dlia korrektsii mikrobnogo statusa u beremennykh zhenshchin.