Cryofibrination: did it really happen?
Cryofibrin precipitation is a phenomenon which has only recently been described, although it might have been present since the advent of membrane oxygenators for cardiopulmonary bypass procedures. The deposition of the cold-reactive protein, cryofibrin, causes progressive occlusion of the heat-exchanger part of the cardiopulmonary circuit, thus leading to a high pressure-drop phenomenon. We describe our experience with a few cases in which the cryofibrination phenomenon developed while using the 'Avecor-Affinity Medtronic' membrane oxygenator.
Luckraz
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Cardiac Trust Fund, Pamplemousses. hluckraz@hotmail.com
Boolauky
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Mohangee
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D000328:Adult; D002315:Cardiopulmonary Bypass; D011232:Chemical Precipitation; D001026:Coronary Artery Bypass; D003450:Cryoglobulins / Q000737:chemistry*; D004198:Disease Susceptibility; D004868:Equipment Failure; D015199:Extracorporeal Membrane Oxygenation / Q000009:adverse effects* / Q000295:instrumentation; D015241:Fibrinogens, Abnormal / Q000737:chemistry*; D006801:Humans; D007036:Hypothermia, Induced / Q000009:adverse effects*; D007387:Internal Mammary-Coronary Artery Anastomosis; D008297:Male; D008482:Mediastinum; D008875:Middle Aged; D010107:Oxygenators, Membrane; D019106:Postoperative Hemorrhage / Q000209:etiology; D011312:Pressure; D012449:Safety
D003450:Cryoglobulins; D015241:Fibrinogens, Abnormal; C041874:cryofibrinogen