Megistolactone, a new alkaloid from Sarcomelicope megistophylla.
A new quinolone alkaloid, megistolactone (1) was isolated from the bark of Sarcomelicope megistophylla. Its structure has been elucidated on the basis of MS and NMR data. From a biogenetic point of view, this compound should be considered as an oxidation product of 1,2,3,4-tetra-O-subsituted acridone alkaloids, which are also present in the bark.
Fokialakis
N
N
Department of Pharmacy, University of Athens Panepistimiopolis Zografou, Greece.
Magiatis
P
P
Skaltsounis
A L
AL
Tillequin
F
F
Sévenet
T
T
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000737:chemistry* / Q000302:isolation & purification; D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D015363:Quinolones / Q000737:chemistry* / Q000302:isolation & purification; D019685:Rosales / Q000737:chemistry*
D000470:Alkaloids; D015363:Quinolones; C421172:megistolactone; D015107:4-Butyrolactone