title: Effect of the aqueous extract of Rumex patientia on xylol and hyaluronidase induced capillary permeability compared to indomethacin.
abstract: In this study, the effect of an aqueous extract of Rumex patientia L. (Polygonaceae) (D-1) on capillary permeability which was induced by xylol and hyaluronidase was investigated. Experiments were conducted on rabbits according to Monakova and Matusis methods. The effects of D-1 were compared to those of indomethacin, which was used as a control throughout the experiment. Both D-1 (100 mg/kg) and indomethacin (10 mg/kg) were administered orally. As a result, D-1 inhibited capillary permeability, which was induced by xylol and hyaluronidase, and it was found that it was as effective as indomethacin.
authors.affiliation: Department of Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Süleyman
authors.forename: L O
authors.initials: LO
authors.lastname: Demirezer
authors.forename: A
authors.initials: A
authors.lastname: Kuruüzüm
authors.forename: M E
authors.initials: ME
authors.lastname: Büyükokuroğlu
authors.forename: F
authors.initials: F
authors.lastname: Gŏçer
authors.forename: Z N
authors.initials: ZN
authors.lastname: Banoğlu
authors.forename: A
authors.initials: A
authors.lastname: Gepdiremen
mesh_terms: D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects*; D006821:Hyaluronoglucosaminidase / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D019664:Polygonaceae / Q000737:chemistry*; D011817:Rabbits; D014992:Xylenes / Q000494:pharmacology*
chemical_list: D010936:Plant Extracts; D014992:Xylenes; D006821:Hyaluronoglucosaminidase; C026114:2-xylene