title: Argon plasma surgery for the inferior turbinate of patients with perennial nasal allergy.
abstract: OBJECTIVE
  Argon plasma coagulation (APC) is a new electrosurgical modality. The advantages of APC are coagulating of the target tissue without contact and the creation of uniformly deep devitalized and coagulated zones. The objectives of the present study were to determine the clinical effects of APC for the inferior turbinate of patients with nasal allergy and to clarify the histological changes in the mucosa after APC.
  
  
  METHODS
  In a prospective study, 95 patients with perennial nasal allergy were treated with APC. Nasal symptoms and intranasal findings were evaluated preoperatively and 1, 3, and 6 months, and 1 year after the APC. Mucosal specimens from the turbinates were examined under light and electron microscopy.
  
  
  RESULTS
  Nasal stuffiness was improved in 77 of 79 (97.5%) patients after 1 month, in 50 of 51 (98.0%) patients after 3 months, in 20 of 23 (87.0%) patients after 6 months, and in 9 of 12 (75.0%) patients at 1 year after the APC. Rhinorrhea was improved in 46 of 75 (61.3%) patients after 1 month, in 40 of 51 (78.4%) patients after 3 months, in 16 of 21 (76.2%) patients after 6 months, and in 6 of 10 (60.0%) patients at 1 year after the APC. The sneezing was improved in 32 of 54 (59.3%) patients after 1 month, in 21 of 35 (60.0%) patients after 3 months, in 10 of 14 (71.4%) patients after 6 months, and in 6 of 8 (75.0%) patients at 1 year after the APC. In the intranasal findings, congestion of the inferior turbinate improved in 75 of 76 (98.7%) patients after 1 month, in 49 of 52 (94.2%) patients after 3 months, in 20 of 23 (87.0%) patients after 6 months, and in 7 of 11 (63.6%) patients at 1 year after the APC. The nasal discharge was reduced in 40 of 75 (53.3%) patients after 1 month, in 32 of 52 (61.5%) patients after 3 months, in 15 of 22 (68.2%) patients after 6 months, and in 5 of 11 (45.5%) patients at 1 year after the APC. No patients needed nasal packing after the APC.
  
  
  CONCLUSIONS
  This is the first report on the clinical effects of turbinate surgery for nasal allergy using APC. APC was useful fer turbinate surgery of nasal allergy, especially for nasal stuffiness and congestion of the turbinate.
authors.affiliation: Department of Otolaryngology, Hyogo College of Medicine, Nishinomiya, Japan. fukazawa@hyo-med.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Fukazawa
authors.forename: H
authors.initials: H
authors.lastname: Ogasawara
authors.forename: S
authors.initials: S
authors.lastname: Tomofuji
authors.forename: M
authors.initials: M
authors.lastname: Fujii
authors.forename: M
authors.initials: M
authors.lastname: Sakagami
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001128:Argon; D001458:Bandages; D002648:Child; D003094:Collagen / Q000648:ultrastructure; D004564:Electrocoagulation; D004598:Electrosurgery; D004724:Endoscopy; D004848:Epithelium / Q000473:pathology; D005122:Exudates and Transudates; D005260:Female; D005355:Fibrosis; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009297:Nasal Mucosa / Q000473:pathology / Q000601:surgery; D011446:Prospective Studies; D012221:Rhinitis, Allergic, Perennial / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D012912:Sneezing / Q000502:physiology; D014420:Turbinates / Q000473:pathology / Q000601:surgery*
chemical_list: D001128:Argon; D003094:Collagen