[Combined effects caused by chronic exposure to vinyl chloride and dichloroethane].
The authors studied solitary and combined effects of vinyl chloride and dichloroethane in chronic (4 months) inhalation experiment using concentrations of 50 and 500 mg/m3. The experiment revealed general toxic effects including disorders of central nervous system and liver. Those disorders are caused by reductive-oxidative reactions disturbances and dystrophic processes. The authors determined safe combinations of vinyl chloride and dichloroethane concentrations for associated action.
Savchenkov
M F
MF
Lemeshevskaia
E P
EP
Katul'skiĭ
Iu N
IuN
Benemanskiĭ
V V
VV
Zhukova
E V
EV
Pogorelova
I G
IG
Syrosenko
L I
LI
Pankratov
I P
IP
D000818:Animals; D001933:Brain Stem / Q000378:metabolism; D005018:Ethyl Chloride / Q000493:pharmacokinetics / Q000633:toxicity*; D008099:Liver / Q000378:metabolism; D008297:Male; D051381:Rats; D013997:Time Factors; D014752:Vinyl Chloride / Q000493:pharmacokinetics / Q000633:toxicity*
D005018:Ethyl Chloride; D014752:Vinyl Chloride
Kombinirovannoe deĭstvie vinilkhlorida i dikhlorétana pri dlinel'nov postuplenii v ornanizm.