[Extramedullary hematopoiesis as differential mediastinal space-occupying lesion diagnosis].
Intrathoracic extramedullary hematopoiesis is a rare disease in the differential diagnosis of mediastinal masses. It is suggested that asymptomatic masses should not be treated. A correct diagnosis can thus help to avoid an operation. The aim of this case report is to draw attention to this phenomenon as a cause of mediastinal masses and to provide information about diagnostic facilities available. We report the case of a 53-year-old male patient with hereditary spherocytosis as well as the case of a 59-year-old male patient with pyruvate kinase deficiency who showed intrathoracic paravertebral masses, that were identified in the first case by video-assisted thoracoscopic intervention (VATS) and in the second case by thoracotomy as a region of extramedullary hematopoiesis.
Roder
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C
Chirurgische Abteilung, Thoraxklinik-Heidelberg gGmbH, Heidelberg.
Dienemann
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H
D003937:Diagnosis, Differential; D006411:Hematopoiesis, Extramedullary / Q000502:physiology*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D011770:Pyruvate Kinase / Q000172:deficiency; D013103:Spherocytosis, Hereditary / Q000175:diagnosis; D020775:Thoracic Surgery, Video-Assisted; D013906:Thoracoscopy
D011770:Pyruvate Kinase
Die extramedulläre Blutbildung als Differentialdiagnose der mediastinalen Raumforderung.