title: Genetic factors in the genesis of Alzheimer's disease.
abstract: At least four different genes have been identified that are associated with inherited susceptibiltiy to Alzheimer's disease. Some of the genes are highly penetrant (PS1, PS2, beta APP); the other, APOE, is a weaker susceptibility factor. Several additional genes are suspected to exist but have not yet been cloned.
authors.affiliation: Department of Medicine (Division of Neurology), University Health Network, University of Toronto, Toronto, Ontario, Canada M5S 3H2. p.hyslop@utoronto.ca
authors.forename: P H
authors.initials: PH
authors.lastname: St George-Hyslop
mesh_terms: D000544:Alzheimer Disease / Q000209:etiology / Q000235:genetics*; D001923:Brain Chemistry / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D019683:Penetrance