title: Combined iliac angioplasty and infrainguinal revascularization surgery are effective in diabetic patients with multilevel arterial disease.
abstract: The success of percutaneous transluminal angioplasty (PTA) in the treatment of common and external iliac atherosclerotic lesions has been established for the general population. However, several studies have suggested that the presence of diabetes may reduce the effectiveness of iliac angioplasty, particularly in the setting of limb-threatening ischemia requiring concomitant lower extremity revascularization. This study compared the results of iliac artery PTA performed in conjunction with infrainguinal bypass for limb-threatening ischemia for diabetic (DM) and nondiabetic (non-DM) patients. Between 1991 and 2000, 159 PTA were performed in 126 patients (DM = 99/79%, non-DM = 27/21%) in conjunction with subsequent infrainguinal bypass for limb-threatening ischemia (gangrene = 42%, ulcer = 36%, rest pain = 22%). These patients were followed prospectively using a computerized vascular registry. Stents were placed in 34 (21.4%) cases for suboptimal angioplasty results. In this study the combined use of standard surgical and endoluminal modalities for the treatment of multilevel arterial occlusive disease resulted in excellent cumulative patency and limb salvage rates. The presence of diabetes did not alter these favorable results. Multimodal vascular therapy may be used effectively in diabetic patients with limb-threatening ischemia due to multiple levels of arterial occlusion.
authors.affiliation: Department of Surgery, Mount Sinai School of Medicine, New York, NY, USA. peter.faries@mssm.edu
authors.forename: P L
authors.initials: PL
authors.lastname: Faries
authors.forename: D
authors.initials: D
authors.lastname: Brophy
authors.forename: F W
authors.initials: FW
authors.lastname: LoGerfo
authors.forename: C M
authors.initials: CM
authors.lastname: Akbari
authors.forename: D R
authors.initials: DR
authors.lastname: Campbell
authors.forename: L D
authors.initials: LD
authors.lastname: Spence
authors.forename: S C
authors.initials: SC
authors.lastname: Hook
authors.forename: F B
authors.initials: FB
authors.lastname: Pomposelli
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon / Q000009:adverse effects; D001161:Arteriosclerosis / Q000150:complications / Q000628:therapy*; D003925:Diabetic Angiopathies / Q000150:complications / Q000628:therapy*; D005260:Female; D006801:Humans; D017543:Iliac Aneurysm; D007511:Ischemia / Q000150:complications / Q000601:surgery*; D007866:Leg / Q000098:blood supply*; D015993:Life Tables; D008297:Male; D008875:Middle Aged; D015607:Stents; D014654:Vascular Patency; D014656:Vascular Surgical Procedures / Q000009:adverse effects