title: Seroprevalence of Helicobacter pylori infection in a group of hospitalized geriatric patients.
abstract: BACKGROUND
  In recent years several epidemiological surveys have reported the association between Helicobacter Pylori (HP), chronic ischemic heart disease (CHD) and cerebrovascular disease (CVD). None involved the geriatric population in which these diseases are prevalent.
  
  
  METHODS
  We investigated the HP seropositivity prevalence in a group of over 75-year-old subjects recruited among all patients consecutively admitted for various diseases in an Internal Medicine Department during a period of 9 months.
  
  
  METHODS
  We measured HP IgG antibodies employing a commercially available kit based on reverse flow chromatography highly feasible and simple to perform and we investigated all patients for past or present CHD/CVD.
  
  
  RESULTS
  From our data, the prevalence of seropositivity to Hp does not differ from other wider age stratified studies; more in detail; in the over 90-year-old patients we found the same HP seropositivity prevalence as in younger group but were not able to confirm the progressive lowering or seroprevalence in extreme geriatric age.
  
  
  CONCLUSIONS
  No clear correlation between HP seroprevalence and CHD and CVD was found, but a link with CHD seems possible for the determinant (age) is common to both conditions.
authors.affiliation: Department of Internal Medicine, Azienda Ospedaliera Senese Presidio Ospedaliero di Abbadia S. Salvatore, SI, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Biagi
authors.forename: D
authors.initials: D
authors.lastname: Fabbrini
authors.forename: S
authors.initials: S
authors.lastname: Bocchini
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood; D002561:Cerebrovascular Disorders / Q000150:complications / Q000453:epidemiology; D005260:Female; D016481:Helicobacter Infections / Q000150:complications / Q000453:epidemiology* / Q000276:immunology; D016480:Helicobacter pylori / Q000276:immunology; D006760:Hospitalization; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D017202:Myocardial Ischemia / Q000150:complications / Q000453:epidemiology; D016036:Seroepidemiologic Studies
chemical_list: D000907:Antibodies, Bacterial