title: Ventricular enlargement in adults with profound mental retardation who demonstrate violent/destructive behaviors.
abstract: The authors determined brain ventricular size (ventricular brain ratio [VBR]) in 39 ambulatory adult mentally retarded individuals who did or did not require psychotropic medication for violent/destructive behavior. The mean VBR of mentally retarded patients who required psychotropic medication was significantly greater than the VBR of those who did not require such medication.
authors.affiliation: UMDNJ/Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA. maypb@umdnj.edu
authors.forename: P B
authors.initials: PB
authors.lastname: May
authors.forename: K
authors.initials: K
authors.lastname: DeMarco
authors.forename: E B
authors.initials: EB
authors.lastname: London
authors.forename: R
authors.initials: R
authors.lastname: Thompson
authors.forename: T L
authors.initials: TL
authors.lastname: Mento
authors.forename: L
authors.initials: L
authors.lastname: Buscemi
authors.forename: R
authors.initials: R
authors.lastname: Cody
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000187:drug effects / Q000473:pathology; D002552:Cerebral Ventricles / Q000187:drug effects / Q000473:pathology*; D005260:Female; D006801:Humans; D006984:Hypertrophy; D008607:Intellectual Disability / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use; D014754:Violence / Q000523:psychology*
chemical_list: D011619:Psychotropic Drugs