title: A possible pathogenic role of CD8+ T cells and their derived cytokine, IL-16, in SLE.
abstract: Current investigations into the role of CD8+ T cells and their derived cytokine, interleukin (IL)-16, in the induction of CD4+ T cell abnormalities in systemic lupus erythematosus (SLE) were reviewed and discussed on the basis of results mainly obtained in our laboratory.
authors.affiliation: Department of Medicine, Juntendo University Izu-Nagaoka Hospital, Shizuoka, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Sekigawa
authors.forename: M
authors.initials: M
authors.lastname: Matsushita
authors.forename: S
authors.initials: S
authors.lastname: Lee
authors.forename: N
authors.initials: N
authors.lastname: Maeda
authors.forename: H
authors.initials: H
authors.lastname: Ogasawara
authors.forename: H
authors.initials: H
authors.lastname: Kaneko
authors.forename: N
authors.initials: N
authors.lastname: Iida
authors.forename: H
authors.initials: H
authors.lastname: Hashimoto
mesh_terms: D016516:CD4-CD8 Ratio; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D006801:Humans; D019410:Interleukin-16 / Q000276:immunology*; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy / Q000276:immunology*; D008213:Lymphocyte Activation / Q000276:immunology
chemical_list: D019410:Interleukin-16