[Separation of oxetacaine and its metabolites]  .
Oxetacaine (1), known as Tepilta, may be biotransformed to 2-5. After having tried to separate 1-5 by GC we succeeded in finding the HPLC method on Silicagel Si 60 with the eluent MeOH/TBME/HClO4.
Unterhalt
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B
Institut für Pharmazeutische Chemie, Westfälischen Wilhelms-Universität Münster, Germany.
Wenning
C
C
D000779:Anesthetics, Local / Q000302:isolation & purification* / Q000493:pharmacokinetics; D001711:Biotransformation; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D004983:Ethanolamines / Q000302:isolation & purification* / Q000493:pharmacokinetics; D006868:Hydrolysis
D000779:Anesthetics, Local; D004983:Ethanolamines; C100289:oxethazaine
Zur Trennung von Oxetacain und seinen Metaboliten.