[Intraepithelial mononuclear lymphocytes and progression of stomach and colon cancers].
Levels of intraepithelial lymphocytes were assayed in 60 bioptic samples taken from the stomach and colon. The pathologies included non-specific inflammation, benign epithelial proliferation, adenoma with grave epithelial dysplasia and adenocarcinoma. Among the methods used were routine histological staining, direct immunostaining with FITC-conjugated monoclonal antibodies against the human antigen CD4 and antibody Fab-fragment as well as an original procedure for DNA identification. In the colon, adenocarcinoma was distinquishable a high level of intraepithelial CD4(+) lymphocytes while, in the stomach, this was true for tubular adenoma with grave epithelial dysplasia, too.
Nadezhin
A S
AS
State Medical Academy, Yaroslavi.
D003110:Colonic Neoplasms / Q000473:pathology*; D018450:Disease Progression; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000473:pathology*; D013274:Stomach Neoplasms / Q000473:pathology*
Vnutriépitelial'nye mononuklearnye leĭkotsity i stepen' progressii raka zheludka i tolstoĭ kishki.