title: Effect of amine fluoride on enamel surface morphology.
abstract: In this in vitro study, examination of the enamel surface morphology after topical application of an amine fluoride solution with different fluoride (F) content was carried out. Sound human enamel slabs were treated with an amine fluoride solution containing either 1.0, 0.5 or 0.25% F for 3 min. during 3 days. All slabs were examined using scanning electron microscopy and energy-dispersive spectroscopy (SEM/EDS) qualitative analysis. The globular precipitates were revealed in all treated specimens, regardless of F content. The distribution of the deposits was more homogeneous in groups treated with higher concentrations; however, the globules were larger and more cubical in groups treated with lower fluoride concentrations. These larger globules could be less soluble and thus serve as a fluoride reservoir for a more extended period and so they could contribute to the caries preventive effect in professional topical products with lower fluoride concentration. Following the 24-hour treatment with KOH the precipitates could be removed; however, the enamel surfaces covered with the precipitates were less degraded than the untreated enamel. The EDS qualitative analysis showed that the intensities of fluoride signals were increased with the higher concentration of fluoride in an amine fluoride solution, while the intensities of calcium signals were decreased. The enamel surface precipitates were alkali-soluble, but we were not able to demonstrate that they are pure calcium fluoride.
authors.affiliation: Department of Pharmacology, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
authors.forename: K
authors.initials: K
authors.lastname: Rosin-Grget
authors.forename: I
authors.initials: I
authors.lastname: Lincir
authors.forename: M
authors.initials: M
authors.lastname: Tudja
mesh_terms: D002118:Calcium / Q000378:metabolism; D002327:Cariostatic Agents / Q000494:pharmacology*; D011232:Chemical Precipitation; D003743:Dental Enamel / Q000187:drug effects* / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D005460:Fluorides, Topical / Q000494:pharmacology*; D006801:Humans; D008854:Microscopy, Electron; D008963:Molar
chemical_list: D002327:Cariostatic Agents; D005460:Fluorides, Topical; C094808:amine fluoride solution; D002118:Calcium