Retrospective review of serologic rubella activity in University Hospital Kuala Lumpur.
A retrospective review of rubella serological results carried out in the Virus Diagnostic Unit, University Hospital Kuala Lumpur (UHKL) from January 1993 to September 1999 showed the presence of rubella infection annually which appeared to increase periodically every two to three years. There was no statistical significant difference in the rubella positive rate between male and female population aged 14 to 48 years. Congenital rubella infections (CRI) occurred in babies delivered in UHKL yearly from 1993 to 1998 with an average incidence rate of 48 per 100,000 deliveries. Peaks of rubella cases appeared to be followed by an increase in incidence of CRI cases 6 to 9 months later. The study showed that only 50.8% clinically diagnosed rubella was confirmed by laboratory finding. This study also showed an increase of rubella activity for the months of July, August and September 1999 and this may herald an increase of CRI cases in the coming millennium.
Chua
K B
KB
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur.
Lam
S K
SK
Hooi
P S
PS
Chua
B H
BH
Lim
C T
CT
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D015994:Incidence; D008296:Malaysia; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology; D012189:Retrospective Studies; D012409:Rubella / Q000151:congenital / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D012698:Serologic Tests; D014611:Vaccination / Q000592:standards