[Epileptoform EEG activity: occurrence under sevoflurane and not during propofol application].
In a 62-year-old female patient without a history of epileptic seizures EEG monitoring (EEG monitor: Narcotrend) was routinely performed during propofol/remifentanil and during sevoflurane/remifentanil/nitrous oxide anaesthesia. In the first course of anaesthesia after a bolus of propofol 1% a continuous EEG slowing was followed by a burst suppression pattern without occurrence of epileptiform activity throughout this sequence. During the second course of anaesthesia the sevoflurane concentration was increased from 2 to 8 % by volume. After 5 min epileptiform activity appeared in the EEG at an endtidal concentration of 5.9% by volume.
Schultz
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B
Medizinische Hochschule Hannover, Abteilung Anästhesie IV. Barbara.Schultz@narcotrend.de
Schultz
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A
Grouven
U
U
Korsch
G
G
D000769:Anesthesia, Inhalation / Q000009:adverse effects*; D000771:Anesthesia, Intravenous / Q000009:adverse effects*; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D018686:Anesthetics, Intravenous / Q000009:adverse effects*; D004569:Electroencephalography / Q000187:drug effects*; D004827:Epilepsy / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008738:Methyl Ethers / Q000009:adverse effects*; D008875:Middle Aged; D015742:Propofol / Q000009:adverse effects*; D000077149:Sevoflurane
D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D008738:Methyl Ethers; D000077149:Sevoflurane; D015742:Propofol
Epilepsietypische EEG-Aktivität: Auftreten bei Sevofluran-anflutung und nicht unter Propofolapplikation.