title: [Familial Mediterranean fever: report of a case].
abstract: Familial Mediterranean fever is an autosomal recessive hereditary disease characterised by recurrent fever, poliserositis, chest and/or abdominal pain. Up to date diagnosis is based on clinical symptoms, familial anamnesis and response to colchicine. It is an inflammatory reaction affecting serosal tissues but until recently different hypotheses have been suggested to explain the greatly increased chemotactic activity of the polymorfonuclear leucocytes. Identification of the function of the MEFV gene on chromosome 16 and its protein allows us to understand the pathogenesis of familial Mediterranean fever as well as provides a new diagnostic test and therapeutic measures. We describe a case of an young patient and review the literature.
authors.affiliation: Divisione Medicina, Ospedale A. Gallino, Genova, Ponte X, Italia.
authors.forename: M P
authors.initials: MP
authors.lastname: Parodi
authors.forename: T
authors.initials: T
authors.lastname: Coialbu
authors.forename: M
authors.initials: M
authors.lastname: Pittaluga
authors.forename: R
authors.initials: R
authors.lastname: Cosso
authors.forename: R
authors.initials: R
authors.lastname: Bevevino
authors.forename: F
authors.initials: F
authors.lastname: Minervini
authors.forename: M
authors.initials: M
authors.lastname: Baffico
mesh_terms: D000293:Adolescent; D010505:Familial Mediterranean Fever / Q000175:diagnosis*; D006801:Humans; D008297:Male
vernacular_title: La febbre mediterranea familiare: descrizione di un caso.