title: Cardiovascular actions of magnesium.
abstract: Intracellular magnesium is an important modulator of calcium and potassium channels in cardiac myocytes. Hypomagnesemia is common in hospitalized patients and may contribute significantly to cardiac morbidity and mortality, particularly in states associated with myocardial ischemia. Therefore, it is important to maintain the plasma magnesium concentration within the normal range in asymptomatic patients and in patients with cardiac disease as prophylaxis against the occurrence of significant arrhythmias.
authors.affiliation: Division of Pediatric Critical Care Medicine, MassGeneral Hospital for Children, Boston, Massachusetts, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Agus
authors.forename: Z S
authors.initials: ZS
authors.lastname: Agus
mesh_terms: D000818:Animals; D001001:Anura; D002319:Cardiovascular System / Q000378:metabolism*; D006168:Guinea Pigs; D006331:Heart Diseases / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D007362:Intensive Care Units; D007473:Ion Channels / Q000502:physiology; D008274:Magnesium / Q000502:physiology* / Q000627:therapeutic use; D008275:Magnesium Deficiency / Q000503:physiopathology; D009206:Myocardium / Q000166:cytology / Q000378:metabolism*
chemical_list: D007473:Ion Channels; D008274:Magnesium