Effects of L-carnitine on nitrogen retention and blood metabolites of growing steers and performance of finishing steers.
Two experiments were conducted to evaluate L-carnitine supplementation to cattle fed grain-based diets. In Exp. 1, seven Angus-cross steers (216 kg) were used in a 7 x 4 incomplete Latin square experiment to evaluate the effects of supplemental L-carnitine on N balance and blood metabolites. Steers were fed a corn-based diet (17.5% CP) at 2.5% of BW. Treatments were 0, 0.25, 0.5, 1.0, 1.5, 2.0, and 3.0 g/d of supplemental carnitine. The 18-d periods included 13 d for adaptation and 5 d for collection of feces and urine. Blood was collected before feeding and 3 and 6 h after feeding on d 18 of each period. Dry matter intakes tended to be highest when 1.5 g/d of carnitine was supplied, but N retention was not affected by carnitine and averaged 29.3 g/d. Plasma carnitine concentrations and urinary excretion increased with increasing carnitine supply, indicating that at least some of the carnitine escaped ruminal degradation and was absorbed by the steers. Plasma concentrations of NEFA demonstrated a treatment x time interaction; they decreased linearly in response to carnitine before feeding but increased linearly in response to carnitine at 6 h after feeding. Serum insulin and plasma glucagon, IGF-I, cholesterol, triglyceride, and amino acids were not affected by carnitine. Plasma concentrations of glucose, glycerol, urea, and beta-hydroxybutyrate all were increased by some of the levels of carnitine supplementation, but results for these measurements did not follow easily described patterns and seemed to be related to differences in DMI. In Exp. 2, 95 crossbred steers (357 kg initial BW) were fed finishing diets (14.5% CP) for 129 d. Diets were based on steam-flaked corn and contained 6% alfalfa and 4% tallow. Feed intakes, gains, and feed efficiencies were not affected by supplementation with 2 g/d L-carnitine. However, steers receiving L-carnitine tended to have fatter carcasses, as indicated by tendencies (P < 0.2) for thicker backfat, higher marbling scores, and higher yield grades. In conclusion, carnitine supplementation did not alter lean deposition in growing steers but it did alter plasma NEFA concentrations of growing steers fed a corn-based diet and also seemed to increase fat deposition in finishing cattle.
Greenwood
R H
RH
Department of Animal Sciences and Industry, Kansas State University, Manhattan 66506-1600, USA.
Titgemeyer
E C
EC
Stokka
G L
GL
Drouillard
J S
JS
Löest
C A
CA
D020155:3-Hydroxybutyric Acid / Q000097:blood; D000596:Amino Acids / Q000097:blood; D000821:Animal Feed; D000818:Animals; D002331:Carnitine / Q000378:metabolism / Q000494:pharmacology*; D002417:Cattle / Q000097:blood / Q000254:growth & development* / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D019587:Dietary Supplements; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005934:Glucagon / Q000097:blood; D007328:Insulin / Q000097:blood; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D008297:Male; D009584:Nitrogen / Q000378:metabolism*; D014280:Triglycerides / Q000097:blood; D014508:Urea / Q000097:blood
D000596:Amino Acids; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D014280:Triglycerides; D007334:Insulin-Like Growth Factor I; D014508:Urea; D005934:Glucagon; D002784:Cholesterol; D009584:Nitrogen; D002331:Carnitine; D020155:3-Hydroxybutyric Acid