title: Occurrence of asymptomatic microscopic haematuria in a filarial endemic area of Orissa, India.
abstract: To determine the frequency of occurrence of asymptomatic microscopic haematuria in filarial endemic area of Orissa, where the mf rate and disease rate were observed to be 14.8% and 37.2% respectively, clinical examination, night blood smear examination, morning midstream urine examination were conducted on 697 persons-randomly selected from all age groups in 8 villages of Puri tehsil. Out of them, 15.6% were found to have asymptomatic haematuria (Grade I-14.7%, Grade II-0.6%, Grade-III 0.3%). The prevalence of asymptomatic microscopic haematuria was observed to have positive statistical correlation with mf status (P < 0.001), filarial antigenaemia (Ag) (P < 0.001), antibody (Ab) (P < 0.001) and circulating immunocomplex antigen (CIC-Ag) (P < 0.001). The prevalence was also found to be increased with the progression of the disease process i.e. from endemic normal to chronic manifestations. None of the cases having Grade-II and III haematuria cases revealed any gross renal pathological lesions, when subjected to special investigations like X-ray, IVP, cystoscopy and urethroscopy.
authors.affiliation: Division of Clinical Pathology & Microbiology, Regional Medical Research Centre (ICMR), Chandrasekharpur, Bhubaneshwar-751016.
authors.forename: G P
authors.initials: GP
authors.lastname: Chhotray
authors.forename: M R
authors.initials: MR
authors.lastname: Ranjit
authors.forename: M
authors.initials: M
authors.lastname: Mohapatra
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004605:Elephantiasis, Filarial / Q000453:epidemiology* / Q000469:parasitology; D019353:Endemic Diseases; D005260:Female; D006417:Hematuria / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D014958:Wuchereria bancrofti / Q000254:growth & development / Q000302:isolation & purification