Primary intradural classic chondrosarcoma: case report and literature review.
OBJECTIVE
The exact origin of rare intradural chondrosarcomas remains obscure. We present a case report of an intradural classic chondrosarcoma (a very rare subtype of chondrosarcoma in this location), with a review of the literature, in an attempt to clarify the histogenesis of these tumors.


METHODS
A 48-year-old man presented with a 12-month history of progressive right hemiparesis. Computed tomography and magnetic resonance imaging demonstrated a left parietal space-occupying lesion.


METHODS
The patient underwent an image-guided, left parietal parasagittal craniotomy. An extrinsic tumor, which seemed to arise from the dura, was macroscopically removed. There was no bone involvement. The histological examination revealed a Grade II classic chondrosarcoma with tumor infiltration into the dura. Adjuvant radiotherapy was administered.


CONCLUSIONS
Intradural chondrosarcomas are rare tumors, the majority of which are mesenchymal. Classic chondrosarcomas in this location are much rarer. Their histogenesis is uncertain. In this case, the origin seems to be from the dura. Because of the malignant potential of these tumors, radical extirpation whenever possible, followed by radiotherapy, is indicated.
Bosma
J J
JJ
Department of Neurosurgery, Walton Centre for Neurology and Neurosurgery, Liverpool, England. bosma-j@wcnn.tr.nwest.nhs.uk
Kirollos
R W
RW
Broome
J
J
Eldridge
P R
PR
D002813:Chondrosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D004388:Dura Mater / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D014057:Tomography, X-Ray Computed