Crystal deposition in normal and diseased articular cartilage: an extended report.
Particles observed on the surfaces of human articular cartilage following trauma and from chondromalacic, osteoarthritic and rheumatoid joints using the scanning electron microscope were analysed by x-ray diffraction technique. The particles contained calcium and phosphorus and they were identified only in structurally abnormal cartilage. These findings suggest that local abnormality of articular cartilage probably underlies crystal-deposition.
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Glenfield Hospital, Groby Road, Leicester, U.K.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging / Q000473:pathology*; D001706:Biopsy; D002118:Calcium / Q000032:analysis*; D002357:Cartilage Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D002358:Cartilage, Articular / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology*; D016022:Case-Control Studies; D002805:Chondrocalcinosis / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007718:Knee Injuries / Q000000981:diagnostic imaging / Q000473:pathology*; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D010003:Osteoarthritis / Q000000981:diagnostic imaging / Q000473:pathology*; D010758:Phosphorus / Q000032:analysis*; D011859:Radiography; D014961:X-Ray Diffraction
D010758:Phosphorus; D002118:Calcium