title: [Laxigal effectiveness in constipation of various etiology].
abstract: The efficiency of laxigal (sodium picosulfate) was evaluated in 66 patients aged 38-73 years with the irritated bowel syndrome (IBS), inert colon, and dolichocolon. Twenty-eight patients had defecations twice a week, 26 once a week or less. Twelve patients had no spontaneous defecations. Laxigal was administered in a dose of 10-24 droplets before sleeping. Good effect was attained in 42 (64%) patients and satisfactory in 24 (36%). Good effect is more often observed in patients with IBS and dolichocolon, while in patients with inert colon the results were usually no better than satisfactory. After long (3 weeks and longer) therapy with laxigal its dose could be reduced by 30-50% without loss of effect. Laxigal induces no diarrhea, abdominal pain, decrease in electrolyte composition or other serum shifts, does not disorder hepatorenal functions.
authors.forename: A I
authors.initials: AI
authors.lastname: Parfenov
authors.forename: N I
authors.initials: NI
authors.lastname: Poleva
mesh_terms: D000328:Adult; D000368:Aged; D002400:Cathartics / Q000627:therapeutic use*; D002908:Chronic Disease; D002951:Citrates; D003248:Constipation / Q000188:drug therapy* / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007420:Intestine, Large / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D010847:Picolines / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D002400:Cathartics; D002951:Citrates; D009942:Organometallic Compounds; D010847:Picolines; C005701:picosulfate sodium
vernacular_title: Effektivnost' laksigala pri zaporakh razlichnogo geneza.