title: Biocomposition and reaction of pulp tissues to restorative treatments.
abstract: Dentistry has experienced exponential growth in the biologic and physiologic knowledge of enamel, dentin, and pulp tissues. In one decade, material development has exceeded clinical testing limits, allowing their arrival to the commercial market without proper validation. This article clarifies the enigma of acid etching; explaining and clarifying the diverse opinions and issues of material toxicity between in vitro and in vivo usage test perspectives. This article also demystifies the biology of pulp healing regarding calcium hydroxide and adhesive systems to promote dentin bridge formation. Lastly, this article provides biologically lucid pulp exposure treatment regimens with agents such as NaOCl, allowing clinicians to increase their long-term clinical success.
authors.affiliation: Department of Comprehensive Care, Endodontics, and Pulp Biology, University of Alabama at Birmingham School of Dentistry, Birmingham, Alabama, USA. chasfcox@uab.edu
authors.forename: C F
authors.initials: CF
authors.lastname: Cox
authors.forename: A A
authors.initials: AA
authors.lastname: Hafez
mesh_terms: D000134:Acid Etching, Dental; D000269:Adhesives / Q000737:chemistry; D001672:Biocompatible Materials / Q000633:toxicity; D002126:Calcium Hydroxide / Q000737:chemistry; D003743:Dental Enamel / Q000187:drug effects / Q000502:physiology; D003764:Dental Materials / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D003782:Dental Pulp / Q000187:drug effects / Q000502:physiology*; D003789:Dental Pulp Exposure / Q000628:therapy; D003793:Dental Restoration, Permanent; D003804:Dentin / Q000187:drug effects / Q000502:physiology; D003809:Dentin, Secondary / Q000502:physiology; D004202:Disinfectants / Q000627:therapeutic use; D006801:Humans; D012973:Sodium Hypochlorite / Q000627:therapeutic use; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D000269:Adhesives; D001672:Biocompatible Materials; D003764:Dental Materials; D004202:Disinfectants; D012973:Sodium Hypochlorite; D002126:Calcium Hydroxide