title: [Some prognostic factors in the combined therapy of locally advanced breast cancer].
abstract: A relationship between the dynamics of growth and pathological response of tumor cells and the number of neoadjuvant chemotherapy courses was established. As a result, there was no correlation between increase in overall and disease-free survival, on the one hand, and stage, on the other. An interval between neoadjuvant chemotherapy and surgery longer than 4 weeks had a negative effect on overall tumor response and duration of disease-free period.
authors.affiliation: Russian Center for Roentgenology Research, Ministry of Health of the RF, Moscow.
authors.forename: E K
authors.initials: EK
authors.lastname: Voznyĭ
authors.forename: V P
authors.initials: VP
authors.lastname: Kharchenko
authors.forename: S N
authors.initials: SN
authors.lastname: Gurov
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Dobrovol'skaia
authors.forename: S A
authors.initials: SA
authors.lastname: Bol'shakova
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011379:Prognosis; D012307:Risk Factors; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome
vernacular_title: Hekotorye prognosticheskie faktory v kompleksnom lecheniie mestnorasprostranennogo raka molochnoĭ zhelezy.