title: [Extramedullary hematopoiesis as differential mediastinal space-occupying lesion diagnosis].
abstract: Intrathoracic extramedullary hematopoiesis is a rare disease in the differential diagnosis of mediastinal masses. It is suggested that asymptomatic masses should not be treated. A correct diagnosis can thus help to avoid an operation. The aim of this case report is to draw attention to this phenomenon as a cause of mediastinal masses and to provide information about diagnostic facilities available. We report the case of a 53-year-old male patient with hereditary spherocytosis as well as the case of a 59-year-old male patient with pyruvate kinase deficiency who showed intrathoracic paravertebral masses, that were identified in the first case by video-assisted thoracoscopic intervention (VATS) and in the second case by thoracotomy as a region of extramedullary hematopoiesis.
authors.affiliation: Chirurgische Abteilung, Thoraxklinik-Heidelberg gGmbH, Heidelberg.
authors.forename: C
authors.initials: C
authors.lastname: Roder
authors.forename: H
authors.initials: H
authors.lastname: Dienemann
mesh_terms: D003937:Diagnosis, Differential; D006411:Hematopoiesis, Extramedullary / Q000502:physiology*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D011770:Pyruvate Kinase / Q000172:deficiency; D013103:Spherocytosis, Hereditary / Q000175:diagnosis; D020775:Thoracic Surgery, Video-Assisted; D013906:Thoracoscopy
chemical_list: D011770:Pyruvate Kinase
vernacular_title: Die extramedulläre Blutbildung als Differentialdiagnose der mediastinalen Raumforderung.