Recent advances in the understanding of the processing of APP to beta amyloid peptide.
Sinha
S
S
Elan Pharmaceuticals, 800 Gateway Blvd., So. San Francisco, CA 94080, USA. ssinha@elanpharma.com
Anderson
J
J
John
V
V
McConlogue
L
L
Basi
G
G
Thorsett
E
E
Schenk
D
D
D000544:Alzheimer Disease / Q000378:metabolism; D053829:Amyloid Precursor Protein Secretases; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism*; D016282:Aspartic Acid Endopeptidases; D001921:Brain / Q000201:enzymology*; D010450:Endopeptidases / Q000378:metabolism*; D006801:Humans; D011499:Protein Processing, Post-Translational; D011994:Recombinant Proteins / Q000378:metabolism
D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor; D011994:Recombinant Proteins; D053829:Amyloid Precursor Protein Secretases; D010450:Endopeptidases; D016282:Aspartic Acid Endopeptidases; C509280:BACE1 protein, human