The long reach of evolution and development. Effects on the Alzheimer brain.
Genes that cause late-onset neurodegenerative disease may have the property of evolvability. Their tendency to collect mutations may have contributed to the rapid evolution of the brain.
Kosik
K S
KS
Department of Neurology, Harvard Medical School, Boston, Massachusetts 02115, USA. Kosik@cnd.bwh.harvard.edu
D000544:Alzheimer Disease / Q000235:genetics*; D005075:Biological Evolution; D001923:Brain Chemistry / Q000235:genetics*; D006801:Humans; D009154:Mutation / Q000502:physiology