title: The effects of orthostasis on the ventricular-evoked response.
abstract: OBJECTIVE
  The effects of orthostasis on the morphology of the ventricular-evoked response were investigated.
  
  
  RESULTS
  Seven patients (five females; 74.9 +/- 4.6 years) with second- or third-degree atrioventricular block received DDD pacemakers Physios CTM 01 with fractal-coated ventricular leads (both Biotronik, Germany). At their 3-month follow-up sessions, these patients underwent tilt-table tests. Heart rate, mean arterial blood pressure and ventricular-evoked response were measured continuously. Signals were averaged over 15 consecutive beats. Coefficients of correlation between selected ventricular-evoked response parameters and heart rate or mean arterial blood pressure were calculated. Tilt upwards affected heart rate, mean arterial blood pressure and ventricular-evoked response extremes showed non-uniform, patient-specific changes that were not related directly to other parameters. Heart rates significantly increased in six patients following tilt upwards. For all patients, ventricular-evoked response plateau amplitudes immediately increased with tilt upwards. Furthermore, repolarization times correlated with changes in heart rates (r = -0.78).
  
  
  CONCLUSIONS
  Monitoring of the ventricular-evoked response during tilt-table testing revealed that the plateau amplitude of the ventricular-evoked response depends on the patient's position; ventricular-evoked response increased in the upright position and decreased in the supine position. Furthermore, repolarization time and heart rate correlated inversely; higher heart rates resulted in a shortening of the ventricular-evoked response.
authors.affiliation: Medizinische Klinik, Krankenhaus Holweide, Köln, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Saborowski
authors.forename: G
authors.initials: G
authors.lastname: Krahé-Fritsch
authors.forename: M
authors.initials: M
authors.lastname: Krakau
authors.forename: K
authors.initials: K
authors.lastname: Wallbrueck
authors.forename: M
authors.initials: M
authors.lastname: Schaldach
mesh_terms: D000368:Aged; D004244:Dizziness / Q000175:diagnosis* / Q000209:etiology; D005071:Evoked Potentials; D005260:Female; D005500:Follow-Up Studies; D006327:Heart Block / Q000175:diagnosis / Q000628:therapy*; D006339:Heart Rate; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D010138:Pacemaker, Artificial; D011336:Probability; D012680:Sensitivity and Specificity; D018667:Tilt-Table Test / Q000009:adverse effects*