title: Increased incidence of acute ascending aortic dissection with off-pump aortocoronary bypass surgery?
abstract: BACKGROUND
  An apparent increase in the incidence of acute ascending aortic dissection following off-pump coronary artery bypass grafting (OPCAB) led us to assess retrospectively the rate and circumstances of this complication in our institution on a consecutive series of patients undergoing aortocoronary bypass performed with and without extracorporeal circulation (ECC).
  
  
  METHODS
  A retrospective analysis of acute ascending aortic dissections complicating coronary artery bypass grafting surgery in 3,031 patients in our institution since April 1, 1995, was performed using the database of the Montreal Heart Institute.
  
  
  RESULTS
  There was a greater frequency of hypertension in the OPCAB group. Iatrogenic acute aortic dissection occurred in 3 patients among 308 operated on without ECC (0.97%) and 1 patient among 2,723 operated on under ECC (0.04%). This difference was statistically significant (p < 0.00001).
  
  
  CONCLUSIONS
  The risk of aortic dissection may be increased in OPCAB. Careful manipulation of the aorta with a single side-clamping and a control of the arterial pressure should be used to minimize aortic trauma. High-risk patients should undergo CABG without side-clamping of the aorta or CABG with ECC to prevent this redoubtable complication of myocardial revascularization.
authors.affiliation: Department of Surgery, Research Center, Montreal Heart Institute, Quebec, Canada.
authors.forename: O
authors.initials: O
authors.lastname: Chavanon
authors.forename: M
authors.initials: M
authors.lastname: Carrier
authors.forename: R
authors.initials: R
authors.lastname: Cartier
authors.forename: Y
authors.initials: Y
authors.lastname: Hébert
authors.forename: M
authors.initials: M
authors.lastname: Pellerin
authors.forename: P
authors.initials: P
authors.lastname: Pagé
authors.forename: L P
authors.initials: LP
authors.lastname: Perrault
mesh_terms: D000368:Aged; D000784:Aortic Dissection / Q000209:etiology*; D001011:Aorta / Q000293:injuries; D001014:Aortic Aneurysm / Q000209:etiology* / Q000473:pathology; D002315:Cardiopulmonary Bypass; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000379:methods; D003327:Coronary Disease / Q000601:surgery; D005260:Female; D006801:Humans; D022125:Lacerations / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies