title: Hyperaldosteronism in a cat with metastasised adrenocortical tumour.
abstract: In a 12-year-old male shorthaired cat with attacks of hypokalaemic muscular weakness in spite of oral potassium supplementation, highly elevated plasma aldosterone concentrations in combination with low plasma renin activity pointed to primary hyperaldosteronism. Ultrasonography and computed tomography revealed a large left-sided adrenal tumour growing into the phrenicoabdominal vein and the caudal vena cava. The tumour and its intravascular extension were surgically removed, but the subsequent stenosis of the caudal vena cava caused congestion and renal failure. At autopsy pulmonary micrometastases of the aldosteronoma were found.
authors.affiliation: Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University. A.Rijnberk@vet.uu.nl
authors.forename: A
authors.initials: A
authors.lastname: Rijnberk
authors.forename: G
authors.initials: G
authors.lastname: Voorhout
authors.forename: H S
authors.initials: HS
authors.lastname: Kooistra
authors.forename: R J
authors.initials: RJ
authors.lastname: van der Waarden
authors.forename: F J
authors.initials: FJ
authors.lastname: van Sluijs
authors.forename: J
authors.initials: J
authors.lastname: IJzer
authors.forename: P
authors.initials: P
authors.lastname: Boer
authors.forename: W H
authors.initials: WH
authors.lastname: Boer
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism / Q000662:veterinary*; D000311:Adrenal Glands / Q000000981:diagnostic imaging / Q000473:pathology; D000450:Aldosterone / Q000097:blood / Q000378:metabolism; D000818:Animals; D002277:Carcinoma / Q000000981:diagnostic imaging / Q000378:metabolism / Q000556:secondary / Q000662:veterinary*; D002371:Cat Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000209:etiology; D002415:Cats / Q000097:blood*; D003251:Constriction, Pathologic / Q000209:etiology / Q000662:veterinary; D017809:Fatal Outcome; D006929:Hyperaldosteronism / Q000000981:diagnostic imaging / Q000209:etiology / Q000662:veterinary*; D007008:Hypokalemia / Q000209:etiology / Q000662:veterinary; D008175:Lung Neoplasms / Q000556:secondary / Q000662:veterinary; D008297:Male; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D019043:Vascular Neoplasms / Q000556:secondary / Q000601:surgery / Q000662:veterinary; D014682:Vena Cava, Inferior / Q000473:pathology
chemical_list: D000450:Aldosterone