title: Presurgical ultrasound-guided anchor-wire marking of soft tissue metastases in stage III melanoma patients.
abstract: BACKGROUND
  Due to increased sensitivity of diagnostic procedures, soft tissue metastases in melanoma patients are frequently detected very early. However, small sizes, deep location, or position close to vulnerable structures could render subsequent surgery quite difficult.
  
  
  OBJECTIVE
  To test the feasibility and effectiveness of presurgical ultrasound-guided anchor-wire marking of melanoma metastases.
  
  
  METHODS
  We selected melanoma patients with cytologically proven metastases in clinical stage III which were either unfavorably located or which have failed removal by previous surgery. Anchor-wire marking was performed ultrasound guided and free-hand style without the use of local anesthesia.
  
  
  RESULTS
  Twelve procedures in nine patients were well tolerated without any complications. In 11 cases the wire tip proved to be located within the tumor lesion; in one case the wire tip missed the target by less than 5 mm and thus was close enough to support appropriate surgery. Earlier, 3 of the 12 study lesions had undergone unsuccessful surgery. The median diameter of the removed metastases was 18.5 mm (range 7-30 mm).
  
  
  CONCLUSIONS
  Ultrasound-guided anchor-wire marking of unfavorably located melanoma metastases is feasible and might facilitate subsequent surgery.
authors.affiliation: Department of Dermatology, Charité, Humboldt University of Berlin, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Voit
authors.forename: T M
authors.initials: TM
authors.lastname: Proebstle
authors.forename: H
authors.initials: H
authors.lastname: Winter
authors.forename: J
authors.initials: J
authors.lastname: Kimmritz
authors.forename: M
authors.initials: M
authors.lastname: Kron
authors.forename: W
authors.initials: W
authors.lastname: Sterry
authors.forename: M
authors.initials: M
authors.lastname: Schwürzer
mesh_terms: D000328:Adult; D000368:Aged; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging* / Q000556:secondary / Q000601:surgery*; D008875:Middle Aged; D011300:Preoperative Care; D012878:Skin Neoplasms / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary / Q000601:surgery*; D014463:Ultrasonography