Identification of QTL affecting important traits on porcine chromosome 12.
To screen the whole porcine chromosome 12 for QTL affecting economically important traits, ten genetic markers were genotyped in two F2 populations generated from the cross of genetically diverse breeds: European Wild pig and commercial pig breed Pietrain (W x P), and Chinese Meishan and Pietrain (M x P). Fifty-one traits were recorded. A least squares method was used for chromosome-wide screening for QTL. An association analysis between genotypes at the GH locus and traits was also carried out. The least squares analysis did not reveal the presence of genome-wide significant QTL affecting the traits, while the association study showed significant (P < 0.01) associations between GH genotypes and fatness traits in M x P, but not in W x P. F2 pigs carrying the genotype C1A2/C4A2 at the GH locus displayed the thinnest backfat (21.76 mm), while the ones carrying the genotype C2A2/C2A2 had the thickest (31.41 mm).
Yue
G H
GH
Department of Animal Breeding and Biotechnology, Institute of Animal Husbandry and Breeding, University of Hohenheim, Germany.
Bartenschlager
H
H
Moser
G
G
Geldermann
H
H
D000818:Animals; D002874:Chromosome Mapping; D008040:Genetic Linkage; D013006:Growth Hormone / Q000235:genetics; D019655:Quantitative Trait, Heritable; D013552:Swine / Q000235:genetics*
D013006:Growth Hormone