title: A preliminary functional brain study on amputees.
abstract: The purpose of this study was to verify whether brain activation could be used to modulate the movements of an artificial limb. This approach was begun 20 years ago with the fitting of prostheses immediately following lower-limb amputations. We studied 9 unilateral amputees and 9 control participants using functional MRI, electroneuromyography, gait laboratory, and neuropsychological assessments. The results demonstrated that brain activation is analogous when participants in the control group are asked to mentally move a foot, compared with amputees who are asked to move a nonexistent foot. The brain has not been damaged and maintains its areas of command. This can be applied in rehabilitation.
authors.affiliation: SARAH Network of Hospitals for the Locomotor System, Brasília, Brazil.
authors.forename: A C
authors.initials: AC
authors.lastname: da Paz
authors.forename: L W
authors.initials: LW
authors.lastname: Braga
authors.forename: J H
authors.initials: JH
authors.lastname: Downs
mesh_terms: D000293:Adolescent; D000328:Adult; D000671:Amputation, Surgical; D001186:Artificial Limbs; D001921:Brain / Q000502:physiology*; D004576:Electromyography; D005260:Female; D005684:Gait / Q000502:physiology; D006801:Humans; D007866:Leg / Q000502:physiology; D008279:Magnetic Resonance Imaging; D008297:Male; D009044:Motor Cortex / Q000502:physiology; D009068:Movement / Q000502:physiology; D009483:Neuropsychological Tests; D010591:Phantom Limb / Q000503:physiopathology