Ventricular enlargement in adults with profound mental retardation who demonstrate violent/destructive behaviors.
The authors determined brain ventricular size (ventricular brain ratio [VBR]) in 39 ambulatory adult mentally retarded individuals who did or did not require psychotropic medication for violent/destructive behavior. The mean VBR of mentally retarded patients who required psychotropic medication was significantly greater than the VBR of those who did not require such medication.
May
P B
PB
UMDNJ/Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA. maypb@umdnj.edu
DeMarco
K
K
London
E B
EB
Thompson
R
R
Mento
T L
TL
Buscemi
L
L
Cody
R
R
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000187:drug effects / Q000473:pathology; D002552:Cerebral Ventricles / Q000187:drug effects / Q000473:pathology*; D005260:Female; D006801:Humans; D006984:Hypertrophy; D008607:Intellectual Disability / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use; D014754:Violence / Q000523:psychology*
D011619:Psychotropic Drugs