title: Identification of QTL affecting important traits on porcine chromosome 12.
abstract: To screen the whole porcine chromosome 12 for QTL affecting economically important traits, ten genetic markers were genotyped in two F2 populations generated from the cross of genetically diverse breeds: European Wild pig and commercial pig breed Pietrain (W x P), and Chinese Meishan and Pietrain (M x P). Fifty-one traits were recorded. A least squares method was used for chromosome-wide screening for QTL. An association analysis between genotypes at the GH locus and traits was also carried out. The least squares analysis did not reveal the presence of genome-wide significant QTL affecting the traits, while the association study showed significant (P < 0.01) associations between GH genotypes and fatness traits in M x P, but not in W x P. F2 pigs carrying the genotype C1A2/C4A2 at the GH locus displayed the thinnest backfat (21.76 mm), while the ones carrying the genotype C2A2/C2A2 had the thickest (31.41 mm).
authors.affiliation: Department of Animal Breeding and Biotechnology, Institute of Animal Husbandry and Breeding, University of Hohenheim, Germany.
authors.forename: G H
authors.initials: GH
authors.lastname: Yue
authors.forename: H
authors.initials: H
authors.lastname: Bartenschlager
authors.forename: G
authors.initials: G
authors.lastname: Moser
authors.forename: H
authors.initials: H
authors.lastname: Geldermann
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D008040:Genetic Linkage; D013006:Growth Hormone / Q000235:genetics; D019655:Quantitative Trait, Heritable; D013552:Swine / Q000235:genetics*
chemical_list: D013006:Growth Hormone