title: Intermittent falls and fecal incontinence as a manifestation of epileptic negative myoclonus in idiopathic partial epilepsy of childhood.
abstract: We report two children, suffering from idiopathic partial epilepsy, who started to present, in the same period of time, with epileptic negative myoclonus (ENM) in one lower limb and fecal incontinence (FI). Polygraphic recordings showed that ENM was associated with paroxysmal activities distributed over the vertex region. Both ENM and FI disappeared when ethosuximide treatment was started. We hypothesize that, in our patients, ENM in one lower limb and FI depended on a transitory impairment, caused by epileptic activity that altered the functionality of nearby cortical areas, located in fronto-mesial regions, involved in the control of the muscular tone of the lower limbs and of the pelvic floor muscles.
authors.affiliation: Department of Child Neuropsychiatry, C. Poma Hospital, Mantova, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Capovilla
authors.forename: G
authors.initials: G
authors.lastname: Rubboli
authors.forename: F
authors.initials: F
authors.lastname: Beccaria
authors.forename: S
authors.initials: S
authors.lastname: Meregalli
authors.forename: P
authors.initials: P
authors.lastname: Veggiotti
authors.forename: P M
authors.initials: PM
authors.lastname: Giambelli
authors.forename: S
authors.initials: S
authors.lastname: Meletti
authors.forename: C A
authors.initials: CA
authors.lastname: Tassinari
mesh_terms: D000058:Accidental Falls; D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004831:Epilepsies, Myoclonic / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D020938:Epilepsy, Partial, Motor / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D005013:Ethosuximide / Q000627:therapeutic use; D005242:Fecal Incontinence / Q000209:etiology*; D005260:Female; D020233:Gait Disorders, Neurologic / Q000209:etiology; D006801:Humans; D008297:Male; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D005013:Ethosuximide