title: [Virucidal activity of disinfectants: virucidal activities of disinfectants on some viruses coated on several materials and its durability].
abstract: First, four disinfectants were tested for virucidal activity on viruses coated upon materials. Disinfectants of the aldehyde and halogen groups had a destructive effect on both enveloped and non-enveloped DNA and RNA viruses coated on a cotton gauze, stainless chips, wood shavings, polyplopylene resin chips and latex resin chips, respectively. Disinfectant of the biguanide group had a virucidal activity on both enveloped DNA and RNA viruses. Secondary, five disinfectants were tested for the durability of their virucidal activity on two DNA and RNA viruses after preparing working solutions. The disinfectants of the aldehyde group maintained their virucidal efficiency for 2 to 3 days. Disinfectants of the invert and amphoteric soap groups, the biguanide group and the halogen group maintained their virucidal efficiency for 1 to 2 days. In the presence of bovine serum, the virucidal activity of the aldehyde group and the halogen group were not influenced but that of the invert and amphoteric soap groups were strongly influenced and lost their effect.
authors.affiliation: Division of 2nd. Microbiology, Hiroshima Prefectural Institute for Public Health and Environment Science.
authors.forename: M
authors.initials: M
authors.lastname: Noda
authors.forename: S
authors.initials: S
authors.lastname: Matsuda
authors.forename: M
authors.initials: M
authors.lastname: Kobayashi
mesh_terms: D000260:Adenoviruses, Human / Q000187:drug effects; D000447:Aldehydes / Q000494:pharmacology; D004267:DNA Viruses / Q000187:drug effects; D004202:Disinfectants / Q000494:pharmacology*; D006678:HIV / Q000187:drug effects; D006219:Halogens / Q000494:pharmacology; D012328:RNA Viruses / Q000187:drug effects; D014780:Viruses / Q000187:drug effects*
chemical_list: D000447:Aldehydes; D004202:Disinfectants; D006219:Halogens