title: Spontaneous vesiculation.
abstract: The thermodynamics of vesicle formation was analyzed by using the elastic bending energy approach. Several different possibilities of spontaneous vesiculation, due to soft bilayers, non-zero spontaneous curvature and Gaussian curvature, respectively, were presented and discussed. Intermediate structures in the closed vesicle-disklike mixed micelle phase transition could be either cup-like particles or open bilayers partially rolled into lipid tubules.
authors.affiliation: Liposome Consultations, Newark, CA, USA. peter.frederik@elmi.unimaas.nl
authors.forename: D D
authors.initials: DD
authors.lastname: Lasic
authors.forename: R
authors.initials: R
authors.lastname: Joannic
authors.forename: B C
authors.initials: BC
authors.lastname: Keller
authors.forename: P M
authors.initials: PM
authors.lastname: Frederik
authors.forename: L
authors.initials: L
authors.lastname: Auvray
mesh_terms: D005732:Gangliosides / Q000737:chemistry; D008051:Lipid Bilayers / Q000737:chemistry; D008081:Liposomes / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry; D013816:Thermodynamics
chemical_list: D005732:Gangliosides; D008051:Lipid Bilayers; D008081:Liposomes; D013501:Surface-Active Agents