title: A study of the liver glucocorticoid receptor binding capacity in newborn rat.
abstract: The binding capacity of newborn and adult rat liver glucocorticoid receptors was compared, using receptor kinetic analysis. Neonatal receptors have (non-significantly) lower affinity and significantly less density to dexamethasone than adult ones. However, the neonatal binding is specific and there is no qualitative difference from the adult one.
authors.affiliation: Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, Hungary.
authors.forename: G
authors.initials: G
authors.lastname: Csaba
authors.forename: A
authors.initials: A
authors.lastname: Inczefi-Gonda
mesh_terms: D000375:Aging / Q000378:metabolism; D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism*; D003600:Cytosol / Q000187:drug effects / Q000378:metabolism; D005260:Female; D008099:Liver / Q000254:growth & development* / Q000378:metabolism*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D011965:Receptors, Glucocorticoid / Q000378:metabolism*
chemical_list: D011965:Receptors, Glucocorticoid