An overview of the prevention of oral cancer and diagnostic markers of malignant change: 2. Markers of value in tumour diagnosis.
Earlier diagnosis of oral cancer should lead to an improvement in prognosis. This, the second part of a two-part overview, is concerned with the various cellular markers available for diagnosis of oral cancer. Traditionally diagnosis has relied upon the histomorphological interpretation of a tissue section following biopsy. The application of advances in various laboratory techniques for the identification of different cellular markers is briefly reviewed. In addition, although it is currently only a research tool, the potential role of oral exfoliative cytology in screening is considered.
Macluskey
M
M
Unit of Oral Surgery and Medicine, Dundee Dental Hospital and School, University of Dundee.
Ogden
G R
GR
D000951:Antigens, Neoplasm / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D001706:Biopsy; D003581:Cytodiagnosis; D004273:DNA, Neoplasm / Q000032:analysis; D006801:Humans; D008403:Mass Screening; D009062:Mouth Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000517:prevention & control*; D009153:Mutagens; D009363:Neoplasm Proteins / Q000032:analysis; D011379:Prognosis
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm; D009153:Mutagens; D009363:Neoplasm Proteins