Enantioseparations in super- and subcritical fluid chromatography.
The separation of chiral compounds by sub- and supercritical fluid chromatography has been a field of great progress since the first demonstration of a chiral separation by SFC in 1985. Almost all of the chiral selectors used in gas or liquid chromatography have been successfully applied to sub-/supercritical chromatography. Easier and faster method development, high efficiency, superior and rapid separations of a wide variety of analytes, extended-temperature capability, analytical and preparative-scale equipment improvements and a selection of detection options have been reported.
Terfloth
G
G
SmithKline Beecham Pharmaceuticals, Research and Development, King of Prussia, PA 19406, USA. gerald_terfloth@sbphrd.com
D002853:Chromatography, Liquid / Q000379:methods*; D013237:Stereoisomerism; D013816:Thermodynamics