Emdogain--periodontal regeneration based on biomimicry.
Biomimicry has been introduced as a term for innovations inspired by nature [1]. Such innovations may appear in almost every part of modern society. This review on the effects of enamel matrix proteins on the formation of cementum and the development of emdogain for regeneration of periodontal tissues lost due to periodontitis shows an example of biomimicry in dentistry. Findings from clinical and laboratory investigations are summarized and the biological basis for enamel matrix-induced periodontal regeneration is discussed.
Gestrelius
S
S
Biora AB, MEDEON, Malmö SE 205 12, Sweden. stina.gestrelius@biora.se
Lyngstadaas
S P
SP
Hammarström
L
L
D002626:Chemistry, Pharmaceutical; D003739:Dental Cementum / Q000187:drug effects; D003746:Dental Enamel Proteins / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D018716:Molecular Mimicry; D009805:Odontogenesis / Q000187:drug effects; D010510:Periodontal Diseases / Q000628:therapy*; D010513:Periodontal Ligament / Q000166:cytology / Q000187:drug effects; D010518:Periodontitis / Q000628:therapy; D010519:Periodontium / Q000187:drug effects; D012038:Regeneration / Q000187:drug effects; D012449:Safety
D003746:Dental Enamel Proteins; C109069:enamel matrix proteins