[Muscarinic receptors in the neostriatum--participation in the operant behavior regulation in dogs].
Exposure of the dogs to signals, data collection and processing were accomplished using a special PC software. Bilateral microinjections of the muscarinic receptors agonists (oxotremorine) into the neostriatum enhanced the tonic component of instrumental movements, suppressed the phasic component and increased the postural component's amplitude. These changes were much more obvious in microinjections of the non-selective muscarinic receptor agonist carbachol due, probably, to its effect on both the M1 and M4 muscarinic receptors of the neostriatum efferent neurones.
Shapovalova
K B
KB
I. P. Pavlov Institute of Physiology, Russian Acad. Sci., 199034, St. Petersburg, Nab. Makarova, 6, Russia.
D000818:Animals; D002217:Carbachol / Q000494:pharmacology; D003071:Cognition / Q000502:physiology; D003216:Conditioning, Operant / Q000502:physiology*; D004285:Dogs; D004924:Escape Reaction / Q000502:physiology; D007839:Functional Laterality; D008845:Microinjections; D009043:Motor Activity / Q000502:physiology; D018721:Muscarinic Agonists / Q000494:pharmacology; D018727:Muscarinic Antagonists / Q000494:pharmacology; D017072:Neostriatum / Q000502:physiology*; D010095:Oxotremorine / Q000494:pharmacology; D011187:Posture / Q000502:physiology; D011930:Reaction Time; D011976:Receptors, Muscarinic / Q000502:physiology*; D012601:Scopolamine / Q000494:pharmacology
D018721:Muscarinic Agonists; D018727:Muscarinic Antagonists; D011976:Receptors, Muscarinic; D010095:Oxotremorine; D002217:Carbachol; D012601:Scopolamine
Muskarinovye retseptory neostriatuma--uchastie v reguliatsii instrumental'nogo povedeniia u sobak.