title: Distribution of upper limb skin cancers in relation to arteriovenous fistula side in renal transplant recipients.
abstract: BACKGROUND
  Renal transplant patients have an increased incidence of skin cancers, predominantly on sun-exposed surfaces. Clinical observation identified some patients with an increased number of viral warts, keratoses, and skin malignancies on the side of the arteriovenous fistula.
  
  
  METHODS
  In a population of 980 patients who underwent transplantation in Oxford, we identified 68 patients with known fistula site who had developed cutaneous malignancies on the upper limbs. We compared the distribution of skin malignancies in relation to the side of the arteriovenous fistula with regard to histologically confirmed Bowen's disease, squamous cell carcinoma, basal cell carcinoma, and keratoacanthoma.
  
  
  RESULTS
  No significant difference was found between the distribution of skin cancers, total malignancies or subgroups, in the fistula limbs compared with the nonfistula limbs.
  
  
  CONCLUSIONS
  We have been unable to demonstrate that the presence of an arteriovenous fistula predisposes to the development of cutaneous malignancies.
authors.affiliation: Nuffield Department of Surgery, John Radcliffe Hospital, Oxford, United Kingdom.
authors.forename: C
authors.initials: C
authors.lastname: Bordea
authors.forename: M
authors.initials: M
authors.lastname: Cortina-Borja
authors.forename: F
authors.initials: F
authors.lastname: Wojnarowska
authors.forename: P J
authors.initials: PJ
authors.lastname: Morris
mesh_terms: D001132:Arm; D001164:Arteriovenous Fistula; D001913:Bowen's Disease / Q000453:epidemiology / Q000209:etiology; D002280:Basal Cell Carcinoma / Q000453:epidemiology / Q000209:etiology; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007636:Keratoacanthoma / Q000453:epidemiology / Q000209:etiology; D016030:Kidney Transplantation / Q000009:adverse effects*; D012307:Risk Factors; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000209:etiology*