[Paraneoplastic syndromes with peripheral nerve involvement].
OBJECTIVE
To review the paraneoplastic complications described affecting the peripheral nervous system.


METHODS
Different types of tumors, especially secretory carcinomas and some lymphomas may affect the peripheral nerves, and this may often precede clinical signs of the tumor. Depending on the clinical features we may consider sensory neuropathies, motor neuropathies, senso-motor neuropathies, autonomic neuropathies, mononeuritis, and neuromyotonia. They may present in an isolated form or as part of a more generalized involvement of the nervous system.


CONCLUSIONS
The presence of certain anti-Hu antibodies, which act against nerves or antibodies which attack the voltage-dependent potassium channels in a peripheral nervous system disorder make one suspect a paraneoplastic origin.
Alvira-Duplá
M R
MR
Sección de Neurología, Servicio de Medicina Interna, Hospital Universitari Joan XXIII, Tarragona, España.
Mayayo-Artal
E
E
D001324:Autoantigens / Q000276:immunology; D002277:Carcinoma / Q000150:complications / Q000276:immunology / Q000378:metabolism; D051959:ELAV Proteins; D006801:Humans; D008223:Lymphoma / Q000150:complications / Q000276:immunology; D016472:Motor Neuron Disease / Q000209:etiology / Q000276:immunology; D009382:Neoplasms, Unknown Primary / Q000150:complications / Q000175:diagnosis; D009419:Nerve Tissue Proteins / Q000276:immunology; D020364:Paraneoplastic Polyneuropathy / Q000209:etiology* / Q000276:immunology; D010525:Peripheral Nerves / Q000276:immunology; D011129:Polyradiculoneuropathy / Q000209:etiology* / Q000276:immunology; D015221:Potassium Channels / Q000276:immunology; D016601:RNA-Binding Proteins / Q000276:immunology; D012678:Sensation Disorders / Q000209:etiology / Q000276:immunology
D001324:Autoantigens; D051959:ELAV Proteins; D009419:Nerve Tissue Proteins; D015221:Potassium Channels; D016601:RNA-Binding Proteins
Síndromes paraneoplásicos con afectación nerviosa periférica.