title: Chronic dacryocystitis in American mucocutaneous leishmaniasis.
abstract: OBJECTIVE
  This study describes lacrimal tract involvement and surgical outcome in patients with mucocutaneous leishmaniasis.
  
  
  METHODS
  Four patients, ages 20 to 75 years, had nasal lesions resulting from mucocutaneous leishmaniasis and sought treatment for chronic dacryocystitis. Each patient had had lacrimal symptoms since childhood or early adulthood, concomitantly with the development of upper airway lesions. Dacryocystography showed nasolacrimal duct stenosis in all cases on the affected side. Three patients underwent dacryocystorhinostomy (one bilaterally), and one patient had bilateral dacryocystectomy.
  
  
  RESULTS
  Two patients had surgical fistula closure soon after surgery. A sequential endoscopic operation for remotion of a synechia between the fistula and the middle turbinate was successful in one of these patients. Histopathologic analysis of lacrimal sacs and nasal mucous membranes close to the anastomotic site revealed chronic nonspecific inflammatory process and negative immunohistochemistry for Leishmania.
  
  
  CONCLUSIONS
  Dacryocystitis may result from nasal mucocutaneous leishmaniasis. The surgical outcome was unsatisfactory in one of the four patients.
authors.affiliation: Department of Ophthalmology, University of São Paulo School of Medicine, Brazil. caramelp@usp.br
authors.forename: C
authors.initials: C
authors.lastname: Baddini-Caramelli
authors.forename: S
authors.initials: S
authors.lastname: Matayoshi
authors.forename: E M
authors.initials: EM
authors.lastname: Moura
authors.forename: D
authors.initials: D
authors.lastname: Araf
authors.forename: R
authors.initials: R
authors.lastname: Santo
authors.forename: R
authors.initials: R
authors.lastname: Voegels
authors.forename: N
authors.initials: N
authors.lastname: Kara-José
mesh_terms: D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002908:Chronic Disease; D003607:Dacryocystitis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology* / Q000601:surgery; D003608:Dacryocystorhinostomy / Q000379:methods; D005260:Female; D006801:Humans; D015994:Incidence; D007897:Leishmaniasis, Mucocutaneous / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009301:Nasolacrimal Duct / Q000000981:diagnostic imaging / Q000601:surgery; D011859:Radiography; D012189:Retrospective Studies