[Antithrombogenic activity of the vascular wall, hemostasis, and rheological characteristics of blood in patients with unstable angina pectoris and various types of hyperlipoproteinemia].
OBJECTIVE
To examine antithrombogenic activity of the vascular wall, some hemostatic and rheological properties of blood in patients with unstable angina (UA) and various types of hyperlipoproteinemia (HLP).


METHODS
102 UA patients were divided into groups by HLP types according to D. S. Frideriksen. Antithrombogenic properties of blood vessel wall were examined with the cuff test, blood rheology--with AKP-2 analyser, hemostasis and lipid metabolism--with standard test.


RESULTS
UA patients with HLP have low antithrombogenic activity of vascular wall. The most noticeable shifts to hypercoagulation were found in patients with HLP types 2a and 2b. Blood rheology was abnormal (high red cell aggregation in low deformability) in patients with HLP types 2a, 2b and 4.


CONCLUSIONS
Patients with UA demonstrate relationships between antithrombogenic activity of vascular wall, intensity of lipid metabolism, hemostasis and blood rheology.
Kirichuk
V F
VF
Voskoboĭ
I V
IV
D000789:Angina, Unstable / Q000097:blood* / Q000150:complications; D001777:Blood Coagulation; D001808:Blood Vessels / Q000378:metabolism*; D004730:Endothelium, Vascular / Q000378:metabolism; D006487:Hemostasis; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000150:complications; D006953:Hyperlipoproteinemia Type IV / Q000097:blood / Q000150:complications; D006951:Hyperlipoproteinemias / Q000097:blood* / Q000150:complications; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation; D012212:Rheology
Antitrombogennaia aktivnost' stenki sosudov, gemostaz i reologicheskie svoĭstva krovi u bol'nykh nestabil'noĭ stenokardieĭ s giperlipoproteinemieĭ razlichnykh tipov.