title: Quantification of immunotoxin number for complete therapeutic response.
authors.affiliation: Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Kreitman
mesh_terms: D036002:ADP Ribose Transferases; D000818:Animals; D000911:Antibodies, Monoclonal; D001427:Bacterial Toxins; D017321:Clinical Trials, Phase I as Topic; D004305:Dose-Response Relationship, Drug; D004354:Drug Screening Assays, Antitumor; D005098:Exotoxins / Q000008:administration & dosage / Q000032:analysis* / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D000922:Immunotoxins / Q000008:administration & dosage / Q000032:analysis* / Q000494:pharmacology / Q000627:therapeutic use; D007279:Injections, Subcutaneous; D007938:Leukemia / Q000188:drug therapy; D007942:Leukemia, Experimental / Q000188:drug therapy; D008223:Lymphoma / Q000188:drug therapy; D051379:Mice; D008819:Mice, Nude; D016513:Mice, SCID; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000188:drug therapy*; D014411:Neoplastic Stem Cells / Q000187:drug effects; D011485:Protein Binding; D015375:Receptors, Interleukin-2 / Q000276:immunology; D011993:Recombinant Fusion Proteins / Q000032:analysis / Q000494:pharmacology / Q000627:therapeutic use; D012074:Remission Induction; D014018:Tissue Distribution; D014162:Transfection; D037521:Virulence Factors; D023041:Xenograft Model Antitumor Assays; D000097668:Pseudomonas aeruginosa Exotoxin A
chemical_list: D036002:ADP Ribose Transferases; D000911:Antibodies, Monoclonal; D001427:Bacterial Toxins; D005098:Exotoxins; D000922:Immunotoxins; D015375:Receptors, Interleukin-2; D011993:Recombinant Fusion Proteins; D037521:Virulence Factors; D000097668:Pseudomonas aeruginosa Exotoxin A; C077707:B3(Fv)-PE38KDEL recombinant immunotoxin