Successful treatment of rhino-orbital mucormycosis without exenteration: the use of multiple treatment modalities.
OBJECTIVE
To describe the successful management of rhino-orbital mucormycosis without the use of orbital exenteration.


METHODS
Case report.


RESULTS
The patient had successful eradication of the fungal infection with retention of normal vision and ocular function.


CONCLUSIONS
The use of multiple treatment modalities including aggressive surgical debridement guided by intraoperative frozen section monitoring, intravenous liposomal amphotericin B, intraorbital regular amphotericin B and hyperbaric oxygen may allow complete resolution of orbital phycomycosis and spare the patient from the blindness and disfigurement associated with exenteration.
Pelton
R W
RW
Department of Ophthalmology, University of Utah Health Sciences Center, Salt Lake City, USA. rwpelton@aol.com
Peterson
E A
EA
Patel
B C
BC
Davis
K
K
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D003646:Debridement; D003937:Diagnosis, Differential; D015821:Eye Infections, Fungal / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D005260:Female; D006801:Humans; D006931:Hyperbaric Oxygenation; D008279:Magnetic Resonance Imaging; D009091:Mucormycosis / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy*; D009916:Orbital Diseases / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy*; D010256:Paranasal Sinuses / Q000601:surgery; D012220:Rhinitis / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy*; D014057:Tomography, X-Ray Computed
D000935:Antifungal Agents