[Measurement of the transcapillary fluid exchange in anesthesized rats].
An experimental model was developed for the study of antiedemic drug activity in anesthetized rats. The effect of furosemide upon the transcapillary fluid shift was studied. It is shown that the character of changes in the arterio-venous difference of blood density in response to postural (orthostatic versus antiorthostatic) changes can be used to udge on the filtration and reabsorption processes in the microcirculation bed of hind extremities in anesthetized rats.
Murashov
A N
AN
Department of Fundamental Medicine, Moscow State University, orob'evy gory, Moscow, 8 Russia.
Biriukov
R I
RI
Khokhlova
O N
ON
Medvedev
O S
OS
D000758:Anesthesia; D000818:Animals; D001158:Arteries; D001809:Blood Viscosity / Q000187:drug effects*; D002199:Capillary Permeability / Q000187:drug effects*; D003720:Densitometry; D004195:Disease Models, Animal; D004487:Edema / Q000188:drug therapy* / Q000378:metabolism; D005665:Furosemide / Q000493:pharmacokinetics / Q000494:pharmacology; D006614:Hindlimb / Q000098:blood supply; D008297:Male; D011187:Posture; D051381:Rats; D017208:Rats, Wistar; D014680:Veins
D005665:Furosemide
Metod izmereniia transkapilliarnogo obmena zhidkosti u narkotizirovannykh krys.