An alternative hypothesis from veterinary science for the pathogenesis of noncarious cervical lesions.
An alternative hypothesis to abrasion and erosion for the pathogenesis of noncarious cervical lesions was put forward in 1984; the so-called occlusal theory suggested that tensile stresses from occlusal overload could be involved in the pathogenesis of noncarious cervical lesions and that bending stresses applied to teeth could cause disruption of the surface enamel, resulting in increased susceptibility to dissolution and abrasion at the affected sites and in the development of wedge-shaped lesions. This theory has gained increased acceptance in recent years, although absolute scientific evidence has been scant. These lesions also occur in animals, in particular, the domestic cat, in which they are called feline odontoclastic resorptive lesions. A variety of theories about pathogenesis of these lesions have been put forward, but there is some evidence that occlusal overload may be a contributory factor in the development of an inflammatory response in the periodontal membrane and the presence of enzymes associated with resorption in the gingival crevice. Further investigation may help define a common etiology between the pathogenesis of feline odontoclastic resorptive lesions and noncarious cervical lesions.
Burke
F J
FJ
University of Glasgow, Dental School, Glasgow, Scotland. f.j.t.burke@bham.ac.uk
Johnston
N
N
Wiggs
R B
RB
Hall
A F
AF
D000135:Acid Phosphatase / Q000032:analysis; D000469:Alkaline Phosphatase / Q000032:analysis; D000818:Animals; D015415:Biomarkers / Q000032:analysis; D002371:Cat Diseases / Q000201:enzymology / Q000209:etiology*; D002415:Cats; D003743:Dental Enamel / Q000473:pathology; D003747:Dental Enamel Solubility / Q000502:physiology; D004195:Disease Models, Animal; D004198:Disease Susceptibility; D005260:Female; D005883:Gingival Crevicular Fluid / Q000201:enzymology; D006801:Humans; D007527:Isoenzymes / Q000032:analysis; D008297:Male; D010010:Osteoclasts / Q000473:pathology; D010518:Periodontitis / Q000201:enzymology / Q000662:veterinary; D013314:Stress, Mechanical; D000071681:Tartrate-Resistant Acid Phosphatase; D014072:Tooth Abrasion / Q000209:etiology / Q000662:veterinary*; D019237:Tooth Cervix / Q000473:pathology*; D014091:Tooth Resorption / Q000201:enzymology / Q000662:veterinary
D015415:Biomarkers; D007527:Isoenzymes; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D000071681:Tartrate-Resistant Acid Phosphatase