A case-control study of Creutzfeldt-Jakob disease in Japan: transplantation of cadaveric dura mater was a risk factor.
A case-control study was conducted to reveal the relative risk of cadaveric dura mater graft transplantation for Creutzfeldt-Jakob disease. Fifty-two cases with Creutzfeldt-Jakob disease that were reported to the surveillance of the disease, and 102 age- and sex-matched hospital controls were selected. Information on family history, occupations, and medical history was collected. Eight cases and no control had a history of cadaveric dura mater graft transplantation. Surgical operations without the dura mater graft, blood transfusion, and acupuncture did not elevate the risk.
Nakamura
Y
Y
Department of Public Health, Jichi Medical School, Tochigi, Japan.
Oki
I
I
Tanihara
S
S
Ojima
T
T
Yanagawa
H
H
Kitamoto
T
T
Sato
T
T
D015670:Acupuncture Therapy; D001803:Blood Transfusion; D002102:Cadaver; D016022:Case-Control Studies; D007562:Creutzfeldt-Jakob Syndrome / Q000453:epidemiology*; D004388:Dura Mater / Q000637:transplantation*; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors