[Atenolol use in gestosis: clinical and hemodynamic aspects].
OBJECTIVE
To study clinical efficiency of atenolol in pregnancy hypertension with consideration of its cardiodynamic effects.


METHODS
The trial included 36 women aged 19 to 41 years on pregnancy week 32 to 38. This study group had gestosis of the 1st and 2nd degree. Control group consisted of 14 healthy women with physiological pregnancy. All the examinees underwent atenolol test: measurement of heart rate, arterial pressure and ECG before, 30 and 90 min after introduction of a single atenolol dose 50 mg. Echo-CG was registered before and 90 min after administration of 50 mg amenolol, and on the treatment day 5.


RESULTS
The response to atenolol in combined therapy of gestosis is the highest in gravidae with hyperkinetic type of circulation.


CONCLUSIONS
Determination of the hemodynamic type is necessary for selection of antihypertensive drugs for treatment of gestosis.
Shekhtman
M M
MM
Elokhina
T B
TB
Petrova
S B
SB
Sokolova
M Iu
MIu
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D001262:Atenolol / Q000627:therapeutic use*; D005260:Female; D005865:Gestational Age; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy* / Q000503:physiopathology; D011379:Prognosis
D000319:Adrenergic beta-Antagonists; D001262:Atenolol
Klinicheskie i gemodinamicheskie aspekty primeneniia atenolola pri gestoze.