title: Recombinant fusion toxins directed against the human granulocyte-macrophage colony stimulating factor (GM-CSF) receptor.
authors.affiliation: Department of Pediatric Hematology, Oncology, and Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Shao
authors.forename: B E
authors.initials: BE
authors.lastname: Warman
authors.forename: J P
authors.initials: JP
authors.lastname: Perentesis
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003001:Cloning, Molecular / Q000379:methods; D003601:Cytotoxicity Tests, Immunologic; D004167:Diphtheria Toxin / Q000235:genetics / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D015195:Drug Design; D019008:Drug Resistance, Neoplasm; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000235:genetics / Q000302:isolation & purification / Q000494:pharmacology / Q000502:physiology / Q000627:therapeutic use*; D006801:Humans; D000922:Immunotoxins / Q000235:genetics / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D007223:Infant; D007376:Interleukin-2 / Q000627:therapeutic use; D007951:Leukemia, Myeloid / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D009363:Neoplasm Proteins / Q000502:physiology; D011065:Poly(ADP-ribose) Polymerases / Q000032:analysis; D021122:Protein Subunits; D016187:Receptors, Granulocyte-Macrophage Colony-Stimulating Factor / Q000037:antagonists & inhibitors* / Q000276:immunology; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents; C054780:DAB(486)-interleukin 2; C114196:DTctGMCSF protein, recombinant; D004167:Diphtheria Toxin; D000922:Immunotoxins; D007376:Interleukin-2; D009363:Neoplasm Proteins; D021122:Protein Subunits; D016187:Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; D011993:Recombinant Fusion Proteins; C078456:denileukin diftitox; D016178:Granulocyte-Macrophage Colony-Stimulating Factor; D011065:Poly(ADP-ribose) Polymerases