title: Quantitative analysis of the electroencephalogram in the intracarotid amobarbital procedure: II. Coherence analysis.
abstract: Thirty-seven subjects underwent bilateral internal carotid artery injections of amobarbital before surgery for intractable epilepsy. The electroencephalograms (EEG) of these patients were continuously monitored during these 74 procedures and were later subjected to quantitative analysis. Analysis of interhemispheric coherence in the delta, theta, alpha, and beta 1 bands was performed. Prominent changes occurred in interhemispheric coherence, which showed a precipitous drop in the first 2 min after amobarbital injection, followed by a gradual return to near baseline levels. These results suggest that interhemispheric relationships are significantly disrupted by intracarotid amobarbital injection.
authors.affiliation: Department of Neurology, University of Arizona Health Sciences Center, Tucson 85724, USA.
authors.forename: G L
authors.initials: GL
authors.lastname: Ahern
authors.forename: D M
authors.initials: DM
authors.lastname: Labiner
authors.forename: D
authors.initials: D
authors.lastname: Talwar
authors.forename: A M
authors.initials: AM
authors.lastname: Herring
authors.forename: M E
authors.initials: ME
authors.lastname: Weinand
mesh_terms: D000293:Adolescent; D000328:Adult; D000654:Amobarbital; D002343:Carotid Artery, Internal; D002540:Cerebral Cortex / Q000187:drug effects / Q000503:physiopathology; D004292:Dominance, Cerebral / Q000187:drug effects* / Q000502:physiology; D004569:Electroencephalography / Q000187:drug effects*; D004827:Epilepsy / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D007269:Injections, Intra-Arterial; D008297:Male; D008875:Middle Aged; D012815:Signal Processing, Computer-Assisted
chemical_list: D000654:Amobarbital