Management of refractory osteoradionecrosis of the jaws with surgery and adjunctive hyperbaric oxygen therapy.
This retrospective study aimed to determine the effectiveness of surgery and hyperbaric oxygen (HBO) treatment in the management of refractory osteoradionecrosis (ORN) of the jaws. Of the 18 patients who had undergone this treatment, 14 patients had complete healing, 3 patients had improved and one patient did not show any improvement. Of the 14 patients who had complete healing, only 4 still had a discontinuity defect of the mandible but they declined additional reconstructive surgery. In conclusion, surgery/HBO therapy showed satisfactory results in the management of refractory ORN of the jaws.
Curi
M M
MM
Department of Stomatology, Centro de Tratamento e Pesquisa Hospital do Câncer, São Paulo, Brazil.
Dib
L L
LL
Kowalski
L P
LP
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D016371:Cranial Irradiation / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006801:Humans; D006931:Hyperbaric Oxygenation; D007571:Jaw Diseases / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010025:Osteoradionecrosis / Q000209:etiology / Q000601:surgery / Q000628:therapy*