Retroperitoneal epithelioid angiosarcoma presenting with lymph node metastases. Clinicopathological study of an extremely rare tumor.
A case of retroperitoneal angiosarcoma in a woman 39 years of age is reported. The tumor presented with inguinal (right) and iliac (left) lymph node metastases and a mass protruding under the left vaginal wall. The unusual morphology of the tumor demanded special immunohistochemical investigation (factor 8, CD 31, CD 34, pancytokeratin 20, LCA, S100, cytokeratin 7, CEA, MU1, HMB 45 and melan A) which confirmed the diagnosis of epithelioid angiosarcoma. The problems in the differential diagnosis and therapeutic approach are discussed.
Sykiotis
K
K
2nd Clinic of Obstetrics and Gynecology, Athens University Areteion Hospital, Greece.
Kondi-Pafitis
A
A
Christodoulakos
G
G
Englezou
M
M
Salamalekis
M
M
D000328:Adult; D015622:Epithelioid Cells / Q000473:pathology; D005260:Female; D006394:Hemangiosarcoma / Q000473:pathology*; D006801:Humans; D008207:Lymphatic Metastasis; D012186:Retroperitoneal Neoplasms / Q000473:pathology*