title: Effects of asymmetric branch flow rates on aerosol deposition in bifurcating airways.
abstract: Representative double bifurcation airway models with asymmetric branch flow rate ratios, caused by spatially different downstream impedances or a carinal tumour in one branch, have been considered. For steady laminar inhalation of a dilute micron-particle suspension, i.e. 500 < or = Re < or = 2000 and 0.02 < or = St < or = 0.12, air flow fields, aerosol distributions, and wall particle concentrations have been simulated with a user-enhanced finite-volume code and an off-line particle tracking routine. Particle deposition efficiencies are shown for both asymmetric branch flow rate cases, i.e. unobstructed and tumour-induced.
authors.affiliation: Center for Environmental Medicine and Lung Biology, UNC, Chapel Hill, NC, USA.
authors.forename: Z
authors.initials: Z
authors.lastname: Zhang
authors.forename: C
authors.initials: C
authors.lastname: Kleinstreuer
authors.forename: C S
authors.initials: CS
authors.lastname: Kim
mesh_terms: D000336:Aerosols; D000403:Airway Resistance / Q000502:physiology; D001980:Bronchi / Q000502:physiology* / Q000503:physiopathology; D003198:Computer Simulation; D005540:Forced Expiratory Flow Rates / Q000502:physiology*; D006801:Humans; D016014:Linear Models; D008954:Models, Biological; D009716:Numerical Analysis, Computer-Assisted; D010316:Particle Size; D015656:Respiratory Mechanics / Q000502:physiology; D014134:Tracheal Neoplasms / Q000503:physiopathology
chemical_list: D000336:Aerosols