title: Mechanical evaluation of a soft tissue interference screw in free tendon anterior cruciate ligament graft fixation.
abstract: In this study of bioabsorbable screw fixation of free tendon grafts used in anterior cruciate ligament reconstruction, we performed load-to-failure and cyclic loading of tendon fixation in porcine bone. Bone density measurements from dual photon absorptometry scans were obtained to correlate bone density with fixation failure. The average density of porcine bone (1.42 g/cm2) was similar to that of young human bone (1.30 g/cm2) and significantly higher than that of elderly human cadaveric bone specimens (0.30 g/cm2). Cyclic loading was performed on free tendon grafts fixed with a bioabsorbable screw alone and on grafts fixed with a bioabsorbable screw and an anchor (polylactic acid ball or cortical bone disk). Stiffness of fixation increased substantially with the addition of a cortical bone disk anchor or polylactic acid ball compared with the interference screw alone. Tensile fixation strength of central quadriceps free tendon and hamstring tendon grafts were significantly superior in porcine bone of density similar to young human bone than in elderly human cadaveric bone. The bioabsorbable interference screw yielded loads at failure comparable with traditional bone-tendon-bone and hamstring tendon fixation when controlled for bone density. The addition of a cortical bone disk anchor provided the most optimal fixation of free tendon with the bioabsorbable screw and reduced slippage with cyclic loading to a very low level.
authors.affiliation: University of Connecticut School of Medicine, Department of Orthopaedic Surgery, Farmington, USA.
authors.forename: D G
authors.initials: DG
authors.lastname: Nagarkatti
authors.forename: B P
authors.initials: BP
authors.lastname: McKeon
authors.forename: B S
authors.initials: BS
authors.lastname: Donahue
authors.forename: J P
authors.initials: JP
authors.lastname: Fulkerson
mesh_terms: D000368:Aged; D000375:Aging; D000818:Animals; D016118:Anterior Cruciate Ligament / Q000601:surgery*; D000070598:Anterior Cruciate Ligament Injuries; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D001863:Bone Screws; D002102:Cadaver; D004868:Equipment Failure; D006085:Graft Survival; D006801:Humans; D013552:Swine; D013710:Tendons / Q000502:physiology / Q000637:transplantation*; D013718:Tensile Strength; D016474:Weight-Bearing
chemical_list: D001672:Biocompatible Materials