title: Urticating Hashimoto-Pritzker Langerhans cell histiocytosis.
abstract: Red-brown papules developing during the neonatal period may present a diagnostic dilemma. The Darier sign has been a reliable feature in the diagnosis of mastocytosis. However, the cutaneous infiltrate of Hashimoto-Pritzker Langerhans cell histiocytosis (LCH) may contain a large number of mast cells, leading to confusion both clinically and histologically. We report an infant who developed red-brown papules of Hashimoto-Pritzker LCH during the neonatal period and presented with a positive Darier sign and acute urticaria.
authors.affiliation: Department of Dermatology, Texas Tech University, Health Sciences Center, Lubbock, Texas 79430, USA.derdfb@ttuhsc.edu
authors.forename: D F
authors.initials: DF
authors.lastname: Butler
authors.forename: B D
authors.initials: BD
authors.lastname: Ranatunge
authors.forename: R P
authors.initials: RP
authors.lastname: Rapini
mesh_terms: D003937:Diagnosis, Differential; D005528:Foot; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007223:Infant; D007866:Leg; D008297:Male; D014581:Urticaria / Q000175:diagnosis* / Q000473:pathology