Comparison of laser in situ keratomileusis and photorefractive keratectomy for the correction of myopia of -6.00 diopters or less. Melbourne Excimer Laser Group.
OBJECTIVE
To evaluate the safety and efficacy of laser in situ keratomileusis (LASIK) compared to photorefractive keratectomy (PRK) for the correction of low or moderate myopia (-0.50 to -6.00 D) at 6 months after surgery.


METHODS
The study population comprised a non-randomized consecutive series of 622 eyes of 392 patients who were treated with the Nidek EC-5000 excimer laser. LASIK was performed using the ACS Chiron microkeratome on 314 eyes and surface PRK on 308 eyes. All patients were treated using a standard protocol, then assessed at 1, 3, and 6 months postoperatively.


RESULTS
Forty-four percent of the LASIK group and 67% of the PRK group attended their 6-month examination. Eighty percent of patients (111 eyes) after LASIK and 65% (136 eyes) after PRK had an uncorrected visual acuity of 20/20 or better. Spherical equivalent refraction was within +/-0.50 D of intended refraction in 78% (109 eyes) for LASIK and 82% (170 eyes) for PRK. Loss of two more lines of best spectacle-corrected visual acuity at 6 months occurred in 1.4% (2 eyes) of the LASIK group and 1.0% (2 eyes) of the PRK group.


CONCLUSIONS
At 1 month follow-up, the percentage of eyes that achieved 20/20 uncorrected visual acuity was greater in the LASIK group than in the PRK group. At 6 months, visual and refractive outcomes of LASIK and PRK were similar. Although flap related complications occurred only after LASIK, the overall risk of loss of best spectacle-corrected visual acuity was not significantly greater than for PRK.
Tole
D M
DM
Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital.
McCarty
D J
DJ
Couper
T
T
Taylor
H R
HR
D000328:Adult; D003315:Cornea / Q000503:physiopathology / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D018903:Photorefractive Keratectomy / Q000379:methods*; D011183:Postoperative Complications; D012029:Refraction, Ocular; D012086:Reoperation; D016896:Treatment Outcome; D014792:Visual Acuity