title: Megistolactone, a new alkaloid from Sarcomelicope megistophylla.
abstract: A new quinolone alkaloid, megistolactone (1) was isolated from the bark of Sarcomelicope megistophylla. Its structure has been elucidated on the basis of MS and NMR data. From a biogenetic point of view, this compound should be considered as an oxidation product of 1,2,3,4-tetra-O-subsituted acridone alkaloids, which are also present in the bark.
authors.affiliation: Department of Pharmacy, University of Athens Panepistimiopolis Zografou, Greece.
authors.forename: N
authors.initials: N
authors.lastname: Fokialakis
authors.forename: P
authors.initials: P
authors.lastname: Magiatis
authors.forename: A L
authors.initials: AL
authors.lastname: Skaltsounis
authors.forename: F
authors.initials: F
authors.lastname: Tillequin
authors.forename: T
authors.initials: T
authors.lastname: Sévenet
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000737:chemistry* / Q000302:isolation & purification; D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D015363:Quinolones / Q000737:chemistry* / Q000302:isolation & purification; D019685:Rosales / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D015363:Quinolones; C421172:megistolactone; D015107:4-Butyrolactone