title: [Histological and immunohistochemical characteristics of diffuse large cell B-cell lymphomas].
abstract: In the REAL classification, diffuse large B-cell non-Hodgkin's lymphomas are grouped together. We investigated histological variants and immunohistochemical profile of diffuse large B-cell lymphomas in 53 patients. Accuracy of the diagnosis was 73.6% without immunohistochemistry. The usefulness of immunophenotyping in making the correct diagnosis depended on a specific histological variant of diffuse large B-cell lymphoma. Variants with polymorphic and anaplastic morphology or massive reactive component have been diagnosed by routine histological methods with poor validity.
authors.affiliation: St-Petersburg Medical Academy of Advanced Medical Education, 193015, St-Petersburg.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Krivolapov
authors.forename: L B
authors.initials: LB
authors.lastname: Saltykova
authors.forename: A A
authors.initials: AA
authors.lastname: Kozlova
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000378:metabolism* / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000378:metabolism* / Q000473:pathology*; D008297:Male; D008875:Middle Aged
chemical_list: D014408:Biomarkers, Tumor
vernacular_title: Gistologicheskaia i immunogistokhimicheskaia kharakteristika diffuznykh krupnokletochnykh B-kletochnykh limfom.