title: Surgery for carotid artery stenosis following neck irradiation.
abstract: Carotid angioplasty and stenting (CAS) is being promoted for patients with carotid artery stenosis who have received neck irradiation. We reviewed our experience with carotid endarterectomy (CEA) following neck irradiation to determine if indeed postoperative and long-term problems were an issue in these patients. Over the past 13 years, 10 patients with a history of neck irradiation underwent 11 procedures. The average time interval between radiation treatment and surgery was 14 years (range 1-44). All carotid arteries were repaired with a standard endarterectomy, eight of which were patched. Three patients had undergone a radical neck dissection on the side ipsilateral to the carotid lesion. They received a pectoral myocutaneous flap (PMF) to protect the carotid artery and optimize wound healing. The lack of perioperative complications and of morbidity indicate that carotid reconstruction for patients with previous neck irradiation is safe and durable. Until long-term favorable results with CAS are available for these patients, operative intervention should remain the standard treatment.
authors.affiliation: Department of Surgical Education, Orlando Regional Medical Center, FL, USA.
authors.forename: M L
authors.initials: ML
authors.lastname: Friedell
authors.forename: B P
authors.initials: BP
authors.lastname: Joseph
authors.forename: M J
authors.initials: MJ
authors.lastname: Cohen
authors.forename: J D
authors.initials: JD
authors.lastname: Horowitz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000528:radiation effects; D016893:Carotid Stenosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D016894:Endarterectomy, Carotid; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000528:radiation effects*; D011183:Postoperative Complications; D011859:Radiography; D011878:Radiotherapy / Q000009:adverse effects; D012189:Retrospective Studies; D015607:Stents; D013524:Surgical Flaps