title: Efficacy of pefloxacin in the treatment of postoperative sepsis in gynaecology.
abstract: Twenty four women with postoperative sepsis following gynaecological surgery were recruited into a study designed to determine the efficacy of Pefloxacin. With the standard oral dose of Pefloxacin, clinical cure or improvement occurred in 98% of the patients. In-vitro, 90% of bacterial isolates were sensitive to Pefloxacin. No adverse effect was encountered in any of the patients. We concluded that Pefloxacin is effective in the treatment of postoperative bacterial infections following gynaecological surgery.
authors.affiliation: Department of Obstetrics and Gynaecology, University College Hospital, Oluyoro Oke-Offa, Ibadan, Nigeria.
authors.forename: A O
authors.initials: AO
authors.lastname: Arowojolu
authors.forename: R A
authors.initials: RA
authors.lastname: Bakare
authors.forename: A A
authors.initials: AA
authors.lastname: Oni
authors.forename: A E
authors.initials: AE
authors.lastname: Ayodele
authors.forename: O O
authors.initials: OO
authors.lastname: Kayode
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects* / Q000706:statistics & numerical data; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015366:Pefloxacin / Q000627:therapeutic use*; D018805:Sepsis / Q000188:drug therapy* / Q000209:etiology*; D016896:Treatment Outcome
chemical_list: D000890:Anti-Infective Agents; D015366:Pefloxacin