Effects of continuous supplementations of ascorbic acid, aspirin, vitamin E and selenium on some haematological parameters and serum superoxide dismutase level in broiler chickens.
1. This study was conducted using male broiler chickens to determine the effects of ascorbic acid, aspirin, ascorbic acid+aspirin, vitamin E+selenium and ascorbic acid+aspirin+vitamin E+selenium supplementations on haematological parameters and serum superoxide dismutase concentration. 2. One hundred and twenty day-old male Hubbunt broiler chicks were randomly divided into 6 experimental groups of 20 chicks each and placed in different pens. Groups 2, 3, 4, 5 and 6 were given a diet supplemented with ascorbic acid, aspirin (in water), ascorbic acid+aspirin, vitamin E+selenium and ascorbic acid+aspirin+vitamin E+selenium, respectively for 45 d while group 1 was given a commercial broiler diet. 3. There was no significant effect of ascorbic acid, aspirin, ascorbic acid+aspirin, vitamin E+selenium supplementations on any of the haematological parameters (red blood cell, haemoglobin, haematocrit, mean corpuscular volume, mean corpuscular haemoglobin concentration, mean corpuscular haemoglobin) in broilers but ascorbic acid+aspirin+vitamin E+selenium supplementation significantly decreased the white blood cell counts. 4. In addition to this, ascorbic acid, aspirin, ascorbic acid+aspirin and ascorbic acid+aspirin+vitamin E+selenium supplementations had no significant effect on the serum superoxide dismutase level, but vitamin E+selenium supplementation increased the serum superoxide dismutase level.
Traş
B
B
Department of Pharmacology, Faculty of Veterinary Medicine,University of Selçuk, Konya, Turkey. btras@selcuk.edu.tr
Inal
F
F
Baş
A L
AL
Altunok
V
V
Elmas
M
M
Yazar
E
E
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000494:pharmacology*; D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology*; D001205:Ascorbic Acid / Q000008:administration & dosage / Q000494:pharmacology*; D001241:Aspirin / Q000008:administration & dosage / Q000494:pharmacology*; D002645:Chickens / Q000097:blood*; D019587:Dietary Supplements; D004906:Erythrocyte Count / Q000662:veterinary; D006400:Hematocrit / Q000662:veterinary; D006454:Hemoglobins / Q000032:analysis; D007958:Leukocyte Count / Q000662:veterinary; D008297:Male; D011897:Random Allocation; D012643:Selenium / Q000008:administration & dosage / Q000494:pharmacology*; D013482:Superoxide Dismutase / Q000097:blood*; D014810:Vitamin E / Q000008:administration & dosage / Q000494:pharmacology*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000975:Antioxidants; D006454:Hemoglobins; D014810:Vitamin E; D013482:Superoxide Dismutase; D012643:Selenium; D001205:Ascorbic Acid; D001241:Aspirin