title: Diagnostic and therapeutic dilemmas of a large scrotal lesion in an AIDS patient.
abstract: In the setting of HIV infection, chronic genital ulcerations may be challenging both diagnostically and therapeutically. The differential diagnosis of these lesions is very broad, and the causes can be multifactorial. We present a case of a chronic, extensive, ulcerating scrotal mass and review the salient clinical, diagnostic, and therapeutic considerations.
authors.affiliation: Dermatology Service, Walter Reed Army Medical Center, Washington, DC, USA.
authors.forename: J D
authors.initials: JD
authors.lastname: Sparling
authors.forename: C W
authors.initials: CW
authors.lastname: Norwood
authors.forename: G W
authors.initials: GW
authors.lastname: Turiansky
authors.forename: C N
authors.initials: CN
authors.lastname: Oster
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000998:Antiviral Agents / Q000627:therapeutic use*; D001706:Biopsy; D000077404:Cidofovir; D003596:Cytosine / Q000031:analogs & derivatives / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D019085:Fluorescent Antibody Technique, Direct; D006558:Herpes Genitalis / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology / Q000821:virology; D018258:Herpesvirus 2, Human / Q000302:isolation & purification; D006801:Humans; D006965:Hyperplasia; D008297:Male; D008875:Middle Aged; D063065:Organophosphonates; D009943:Organophosphorus Compounds / Q000627:therapeutic use*; D012611:Scrotum / Q000473:pathology* / Q000821:virology; D012867:Skin / Q000473:pathology / Q000821:virology; D012883:Skin Ulcer / Q000150:complications* / Q000473:pathology / Q000821:virology
chemical_list: D000998:Antiviral Agents; D063065:Organophosphonates; D009943:Organophosphorus Compounds; D003596:Cytosine; D000077404:Cidofovir