title: [Hepatitis B vaccination. Indications of the post-vaccine serologic test and booster doses].
abstract: The standard anti-HBV vaccination elicits protective anti-HBs levels (above 10 UI/l) in most people. However, the effective duration of immunologic memory is not well-known. Consequently, the recommendations on the postvaccination follow-up are not uniform: from vaccination with no follow-up blood test (anti-HBs levels) to regular follow-up blood tests for all vaccines. In unresponsive subjects a booster dose has been demonstrated to be effective. However, the optimal procedure for management depending anti-HBs levels has not been well established. Postvaccination antibody testing and regular testing for antibodies is recommended only to high-risk subjects, especially to health care workers and subjects with immunodeficiency. In these cases, the booster dose should be administered in nonresponders, and might include double doses. Unanimous consensus does not exist about to the appropriate timing for booster dose administration.
authors.affiliation: Cátedra de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad de Cantabria. jrpallas@mixmail.com
authors.forename: J R
authors.initials: JR
authors.lastname: Pallás Alvarez
authors.forename: M S
authors.initials: MS
authors.lastname: Gómez Holgado
authors.forename: J
authors.initials: J
authors.lastname: Llorca Díaz
authors.forename: M
authors.initials: M
authors.lastname: Delgado Rodríguez
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D006509:Hepatitis B / Q000209:etiology / Q000517:prevention & control*; D017325:Hepatitis B Vaccines / Q000276:immunology*; D006801:Humans; D007117:Immunization, Secondary; D009784:Occupational Diseases / Q000517:prevention & control; D016273:Occupational Exposure; D012307:Risk Factors; D012698:Serologic Tests
chemical_list: D017325:Hepatitis B Vaccines
vernacular_title: Vacunación de la hepatitis B. Indicaciones del test serológico postvacunal y la dosis de refuerzo.