title: The "resin-capture-release" hybrid technique: a merger between solid- and solution-phase synthesis.
abstract: A polymer-assisted organic synthesis that combines the concept of solid-phase synthesis with the idea of polymer-supported scavenging reagents has recently appeared on the chemistry scene. This technique has frequently been termed the "resin-capture-release" methodology and is initiated by the immobilization of a small molecule on a polymeric support. This intermediate is subjected to a second transformation by adding a new reaction partner in solution. This reactant plays two roles: a) the chemical alteration of the polymer-bound intermediate and b) the simultaneous release of this reaction product from the resin back into solution. This new concept is presented and future prospects are discussed.
authors.affiliation: Institut für Organische Chemie, Universität Hannover, Germany. andreas.kirschining@oci.uni-hannover.de
authors.forename: A
authors.initials: A
authors.lastname: Kirschning
authors.forename: H
authors.initials: H
authors.lastname: Monenschein
authors.forename: R
authors.initials: R
authors.lastname: Wittenberg