title: [Testicular seminoma and multifocal aseptic osteonecrosis following chemotherapy].
abstract: BACKGROUND
  Multifocal osteonecrosis has a wide variety of etiologies, but in the cancer patient several risk factors could have a synergic effect (chemotherapy, radiotherapy, corticosteroid, metabolism disorder).
  
  
  METHODS
  A patient with testicular seminoma receiving cisplatin-based chemotherapy and short-term corticosteroid developed multifocal osteonecrosis. Early diagnosis of osteonecrosis is important to prevent orthopedic complications.
  
  
  CONCLUSIONS
  Cisplatin could represent one of the possible etiologies of multifocal osteonecrosis. Magnetic resonance imaging has a high sensitivity and specificity in the diagnosis of osteonecrosis and should be used when this condition is suspected.
authors.affiliation: Service d'oncologie médicale, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice, France. magne@unice.fr
authors.forename: N
authors.initials: N
authors.lastname: Magné
authors.forename: C
authors.initials: C
authors.lastname: Foa
authors.forename: J N
authors.initials: JN
authors.lastname: Bruneton
authors.forename: P Y
authors.initials: PY
authors.lastname: Marcy
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002945:Cisplatin / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010020:Osteonecrosis / Q000139:chemically induced* / Q000473:pathology; D018239:Seminoma / Q000188:drug therapy*; D013736:Testicular Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin
vernacular_title: Séminome du testicule et ostéonécrose aseptique multifocale au décours d'une chimiothérapie.