title: Membranous glomerulonephritis associated with diffuse malignant pleural mesothelioma: report of a case.
abstract: Membranous glomerulonephritis is associated with a variety of malignant neoplasms. However, an association between membranous glomerulonephritis and pleural mesothelioma is very rare. We report herein a case of pleural mesothelioma associated with membranous glomerulonephritis. A 52-year-old man with severe proteinuria was diagnosed to have diffuse malignant pleural mesothelioma. A left extrapleural pneumonectomy was thus performed. The proteinuria resolved postoperatively. However, 6 months postoperatively, the proteinuria recurred. A renal biopsy revealed membranous glomerulonephritis. Simultaneously, a recurrence of the mesothelioma in the left pleural cavity was confirmed. Although rare, membranous glomerulonephritis appears to be one type of paraneoplastic syndrome associated with malignant pleural mesothelioma.
authors.affiliation: Department of Surgery, Hadano Red Cross Hospital, Kanagawa, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sakamoto
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Jojima
mesh_terms: D015433:Glomerulonephritis, Membranous / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000150:complications* / Q000601:surgery; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000150:complications* / Q000601:surgery; D011013:Pneumonectomy; D011507:Proteinuria / Q000209:etiology; D012008:Recurrence