"Duplicate calcaneus": a rare developmental defect observed in several skeletal dysplasias.
Duplication of the calcaneus is a rarely observed radiographic finding that probably results from delayed coalescence of two primary calcaneal centers of ossification. We performed a review of 2,500 computerized cases of skeletal dysplasias and syndromes with bone involvement in the International Skeletal Dysplasia Registry, searching for those cases in which a duplicate calcaneus had been recorded. We found that it was a non-random feature of three skeletal dysplasias and groups comprising thanatophoric dysplasia and the chondrodysplasia punctata and short rib (polydactyly) groups. We conclude that duplication of the calcaneus should be considered a consistent feature of these entities and may reflect a more generalized developmental defect.
Cormier-Daire
V
V
Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California 90048, USA.
Savarirayan
R
R
Unger
S
S
Rimoin
D L
DL
Lachman
R S
RS
D001848:Bone Diseases, Developmental / Q000150:complications* / Q000000981:diagnostic imaging*; D002111:Calcaneus / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D002648:Child; D006801:Humans; D011859:Radiography; D012042:Registries