Hydroxyurea induced leg ulcers.
A 34 years non diabetic lady with chronic myeloid leukaemia (CML) was treated with hydroxyurea and interferon. She developed leg ulcers. First time on left toe and three months later on right foot, a rare complication of hydroxyurea. Both were treated with local wound care and antibiotics. First time dose of hydroxyurea was reduced and second time drug was discontinued.
Abhyankar
D
D
Department of Medical Oncology, Tata Memorial Hospital, Parel, Mumbai-400012.
Shende
C
C
Saikia
T
T
Advani
S H
SH
D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000009:adverse effects* / Q000627:therapeutic use; D007871:Leg Ulcer / Q000139:chemically induced*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy* / Q000473:pathology; D012008:Recurrence; D013163:Splenomegaly
D000970:Antineoplastic Agents; D006918:Hydroxyurea