Ventriculitis due to Cryptococcus uniguttulatus.
Infections due to non-neoformans cryptococci are rare. We report the first case of a human infection caused by Cryptococcus uniguttulatus. Ventriculitis caused by this organism developed in a 65-year-old woman who had had repair of an internal carotid aneurysm. In vitro sensitivity testing showed the Cryptococcus species sensitive to amphotericin B and itraconazole. Treatment with amphotericin led to resolution of the infection.
McCurdy
L H
LH
Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn, USA.
Morrow
J D
JD
D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D020215:Carotid Artery, Internal, Dissection / Q000601:surgery*; D002552:Cerebral Ventricles; D003399:Craniotomy / Q000009:adverse effects*; D003428:Cross Infection / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D003454:Cryptococcus / Q000145:classification*; D004322:Drainage / Q000009:adverse effects*; D004660:Encephalitis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016919:Meningitis, Cryptococcal / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D012008:Recurrence; D012703:Serotyping; D013345:Subarachnoid Hemorrhage / Q000601:surgery*; D014696:Ventriculostomy / Q000009:adverse effects*
D000935:Antifungal Agents; D000666:Amphotericin B