title: Quantification of 3-D coronary arterial motion using clinical biplane cineangiograms.
abstract: Speculation that the motion of the coronary arteries might be involved in the pathogenesis of coronary atherosclerosis has generated growing interest in the study of this motion. Accordingly, a system has been developed to quantify 3-D coronary arterial motion using clinical biplane cineangiograms. Exploiting the temporal continuity of sequential angiographic images, a template matching technique is designed to track the non-uniform frame-to-frame motion of coronary arteries without assuming that the vessels experience uniform axial strain. The implementation of the system is automated by a coarse-to-fine matching process, thus improving the efficiency and objectivity of motion analysis. The system has been validated and employed to characterize the in vivo motion dynamics of human coronary arteries; illustrative results show that this system is a promising tool for routine clinical and laboratory analysis of coronary arterial motion.
authors.affiliation: Biomedical Engineering Center, The Ohio State University, Columbus 43210-1002, USA.
authors.forename: Z
authors.initials: Z
authors.lastname: Ding
authors.forename: M H
authors.initials: MH
authors.lastname: Friedman
mesh_terms: D002932:Cineangiography; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000502:physiology; D006801:Humans; D021621:Imaging, Three-Dimensional; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging