Influence of a high ambient temperature on lipid metabolism in the growing pig.
Because pigs are fatter when they are heat-stressed, it was hypothesized that lipid metabolism is enhanced in heat-stressed pigs. To test this hypothesis, an experiment was conducted to determine the influence of a high ambient temperature on the level of plasma lipids, thyroid hormones, lipoprotein lipase activity, and on the composition of very low density lipoproteins (VLDL) and chylomicrons in the growing pig. Twelve Large White x Landrace castrated male pigs with an initial weight of 20 +/- 0.6 kg were allotted to one of the following treatments: 1) ambient temperature of 31 degrees C, with ad libitum access to feed or 2) ambient temperature of 20 degrees C and fed the amount consumed by those kept at 31 degrees C until 35 kg BW. Ambient temperature did not affect piglet performance. Compared to that in pigs kept at 20 degrees C, in pigs kept at 31 degrees C the lipid content of backfat was 26% higher and the proportion of flare fat was increased by more than twofold (P < 0.001). Lipoprotein lipase activity was increased more than twofold in backfat and nearly twofold in leaf fat at 31 vs 20 degrees C (P < 0.001). In warmth-exposed (31 degrees C), feed-restricted pigs, the plasma level of triiodothyronine was 30% lower than at 20 degrees C (P < 0.001), whereas VLDL-lipid concentration was more than fourfold higher, and plasma concentrations of NEFA and triglycerides were 2.6- and 3.6-fold higher, respectively (P < 0.001). In conclusion, the chronic exposure of growing pigs to a high ambient temperature enhances lipid metabolism in both the liver (VLDL production) and the adipose tissue (lipoprotein lipase activity). Consequently, plasma triglyceride uptake and storage are facilitated in the adipose tissue, which results in greater fatness.
Kouba
M
M
ENSAR, Rennes, France. MARYLINEKOUBA@aol.com
Hermier
D
D
Le Dividich
J
J
D000273:Adipose Tissue / Q000033:anatomy & histology; D000704:Analysis of Variance; D000818:Animals; D002369:Castration; D002914:Chylomicrons / Q000097:blood; D006358:Hot Temperature; D006799:Housing, Animal; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood; D008071:Lipoprotein Lipase / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D013552:Swine / Q000254:growth & development* / Q000378:metabolism; D014284:Triiodothyronine / Q000097:blood
D002914:Chylomicrons; D008055:Lipids; D008079:Lipoproteins, VLDL; D014284:Triiodothyronine; D008071:Lipoprotein Lipase