title: Out-patient behaviour therapy in alcoholism: impact of personality disorders and cognitive impairments.
abstract: OBJECTIVE
  We investigated whether alcoholic patients with comorbid personality disorders and those with cognitive impairments would benefit in a different way from different behaviour therapy strategies.
  
  
  METHODS
  After detoxification, 120 alcoholics were assigned randomly to one of three out-patient treatment programmes comprising 'coping skills training', 'cognitive behaviour therapy' or unspecific supportive control therapy. Personality disorders and cognitive impairments were assessed at the beginning of the 6-month treatment period.
  
  
  RESULTS
  The impact of concomitant personality disorders or cognitive impairments was generally only moderate and mainly independent from treatment condition. However, alcoholic patients relapsing within 6 months after detoxification showed a higher rate of personality disorders (especially antisocial and borderline) and slightly more cognitive deficits (especially in verbal memory and visuomotor functions) than abstainers even before therapy.
  
  
  CONCLUSIONS
  The high amount of early relapses and drop-outs probably hindered larger differentiated treatment effects. Hypotheses will be retested in treatment completers using forthcoming follow-up data.
authors.affiliation: Department of Psychiatry, Heinrich Heine University, Duesseldorf, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Wölwer
authors.forename: W
authors.initials: W
authors.lastname: Burtscheidt
authors.forename: C
authors.initials: C
authors.lastname: Redner
authors.forename: R
authors.initials: R
authors.lastname: Schwarz
authors.forename: W
authors.initials: W
authors.lastname: Gaebel
mesh_terms: D000437:Alcoholism / Q000150:complications* / Q000628:therapy*; D003072:Cognition Disorders / Q000150:complications*; D015928:Cognitive Behavioral Therapy; D003376:Counseling; D005500:Follow-Up Studies; D006801:Humans; D010045:Outpatients / Q000706:statistics & numerical data; D010554:Personality Disorders / Q000150:complications*; D011446:Prospective Studies; D016896:Treatment Outcome