Brain specific proteins in posthaemorrhagic ventricular dilatation.
Median neurofilament and glial fibrillary acidic protein concentrations in the cerebrospinal fluid of 18 infants with posthaemorrhagic ventricular dilatation were 20-200 times higher than control values. S-100 protein in cerebrospinal fluid was four times higher than control values. Glial fibrillary acidic protein concentrations correlated with death or disability and with parenchymal lesions but not with shunt dependence.
Whitelaw
A
A
Division of Child Health, University of Bristol, Bristol, UK. andrew.whitelaw@bristol.ac.uk
Rosengren
L
L
Blennow
M
M
D016022:Case-Control Studies; D002543:Cerebral Hemorrhage / Q000134:cerebrospinal fluid* / Q000150:complications / Q000000981:diagnostic imaging; D002552:Cerebral Ventricles; D002657:Child Development; D004108:Dilatation, Pathologic; D005904:Glial Fibrillary Acidic Protein / Q000134:cerebrospinal fluid*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000134:cerebrospinal fluid* / Q000000981:diagnostic imaging; D016900:Neurofilament Proteins / Q000134:cerebrospinal fluid*; D011237:Predictive Value of Tests; D011379:Prognosis; D009418:S100 Proteins / Q000134:cerebrospinal fluid*; D014463:Ultrasonography; D017287:Ventriculoperitoneal Shunt
D005904:Glial Fibrillary Acidic Protein; D016900:Neurofilament Proteins; D009418:S100 Proteins