Apolipoprotein E and Alzheimer's disease.
The specific molecular pathway by which apolipoprotein E modifies the expression of Alzheimer's disease remains elusive. Isoform-specific interactions of apolipoprotein E with other molecules determine the outcome from other neurologic disorders and may provide more tractable model systems.
Strittmatter
W J
WJ
Division of Neurology, Duke University Medical Center 2900, Durham, North Carolina 27710, USA. warren@neuro.duke.edu
D000544:Alzheimer Disease / Q000235:genetics* / Q000378:metabolism*; D001057:Apolipoproteins E / Q000235:genetics* / Q000378:metabolism*; D001921:Brain / Q000378:metabolism; D006801:Humans
D001057:Apolipoproteins E