[Effect of dilren on hemodynamics of patients with essential hypertension].
Changes in hemodynamics and circadian rhythms in the course of dilren-300 treatment were studied in 20 patients with hypertension stage II. Tetrapolar chest rheography, echo-CG, ECG, measurements of arterial pressure by N. S. Korotkov were made 6 times a days (at 2, 6, 10 a.m. and 2, 6, 10 p.m.). The information was processed statistically. Dilren -300, administered at 8.00 a.m. for 10 days, had a hypotensive, vasodilating and weak negative chronotropic effect. The drug reduced myocardial energy consumption, eliminated circadian rhythms of heart rate, arterial pressure, cardiac performance and others observed before the treatment.
Zaslavskaia
R M
RM
Dorbaeva
D E
DE
Teĭblium
M M
MM
D000368:Aged; D002940:Circadian Rhythm / Q000187:drug effects; D004110:Diltiazem / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*
D014665:Vasodilator Agents; D004110:Diltiazem
Vliianie dil'rena na pokazateli gemodinamiki u bo'nykh gipertonicheskoĭ bolezn'iu.