[Study on casein allergy in children].
Casein a component of milk is used for food additives, industrial materials and drugs. However casein is known to be a main allergen in milk allergy. Recently several cases of anaphylaxis to antibiotics including casein have been reported. In this study we investigated casein allergy in milk allergy. 6 out of 8 patients who were positive for milk RAST were also positive for casein RAST. In these positive cases only 3 out of 6 patients had some allergic symptoms after taking antibiotics. In 3 patients DLST was also positive to casein. There was one patient who was positive in DLST without any symptoms after taking the same antibiotics. It is needed to pay attention to casein allergy when giving the medication which includes casein.
Hasegawa
D
D
Department of Peadiatrics, Tokyo Medical University.
Kawashima
H
H
Oana
S
S
Motobe
M
M
Iiyama
M
M
Kashiwagi
Y
Y
Numabe
H
H
Takekuma
K
K
Hoshika
A
A
D000293:Adolescent; D000707:Anaphylaxis / Q000209:etiology / Q000276:immunology; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D002364:Caseins / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016269:Milk Hypersensitivity / Q000276:immunology*; D011852:Radioallergosorbent Test
D000900:Anti-Bacterial Agents; D002364:Caseins