title: The genome of the archaeal virus SIRV1 has features in common with genomes of eukaryal viruses.
abstract: The virus SIRV1 of the extremely thermophilic archaeon Sulfolobus has a double-stranded DNA genome similar in architecture to the genomes of eukaryal viruses of the families Poxviridae, Pycodnaviridae, and Asfarviridae: the two strands of the 32,301 bp long linear genome are covalently connected forming a continuous polynucleotide chain and 2029 kb long inverted repeats are present at the termini. Very likely it also shares with these viruses mechanisms of initiation of replication and resolution of replicative intermediates.
authors.affiliation: Genzentrum der Ludwig-Maximilians-Universität München, Feodor-Lynen-Str. 25, D-81377 Munich, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Blum
authors.forename: W
authors.initials: W
authors.lastname: Zillig
authors.forename: S
authors.initials: S
authors.lastname: Mallok
authors.forename: H
authors.initials: H
authors.lastname: Domdey
authors.forename: D
authors.initials: D
authors.lastname: Prangishvili
mesh_terms: D001483:Base Sequence; D017124:Conserved Sequence / Q000235:genetics; D004267:DNA Viruses / Q000235:genetics*; D004279:DNA, Viral / Q000235:genetics*; D005057:Eukaryotic Cells / Q000821:virology*; D014644:Genetic Variation / Q000235:genetics; D016679:Genome, Viral; D008969:Molecular Sequence Data; D011212:Poxviridae / Q000235:genetics; D016944:Sulfolobus / Q000821:virology*
chemical_list: D004279:DNA, Viral