[Analysis of general and hemorrhagic complications after treatment of acute proximal deep venous thrombosis of the legs treated with anticoagulants, streptokinase and thrombectomy].
The aim of the study was to present general and haemorrhagic complications in 164 patients with acute DVT in ilio-femoral segment treated with different methods of pharmacological (heparins, streptokinase) and surgical (venous thrombectomy with temporary arterio-venous fistulae) therapy. There were no fatal complications in 48 UH or LMWH treated patients. One patient bled from stress stomach, one developed intramuscular haematoma, one mild pulmonary embolism and one rise of body. Among 84 patients treated with SK five fatal bleeding complications were recorded. From other non fatal complications we recorded one GI bleeding, one splenic rupture and three massive intramuscular haematoma. Three patients died in the early post thrombectomy period. Non fatal complications included one wound haematoma, two wound infection and one with marginal necrosis. The use of LMWH or UH treatment in acute ilio-femoral venous thrombosis is save as the frequency of massive bleeding and serious general complications is rather low. Fatal haemorrhagic episodes are the major hazards of thrombolytic therapy. Venous thrombectomy with temporary arterio-venous fistula may provide a good chance for treatment of acute proximal DVT associated with complete occlusion of the lumen of affected veins in patients with severe ischemic venous thrombosis or with contraindications to heparin treatment.
Meissner
A J
AJ
Misiak
A
A
Huszcza
S
S
Ziemski
J M
JM
D000925:Anticoagulants / Q000009:adverse effects*; D005343:Fibrinolytic Agents / Q000009:adverse effects; D006406:Hematoma / Q000139:chemically induced; D006470:Hemorrhage / Q000209:etiology*; D006493:Heparin / Q000009:adverse effects; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control; D011655:Pulmonary Embolism / Q000139:chemically induced; D013300:Streptokinase / Q000009:adverse effects*; D013530:Surgical Wound Infection / Q000209:etiology; D017131:Thrombectomy / Q000009:adverse effects* / Q000379:methods; D013924:Thrombophlebitis / Q000628:therapy*
D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006493:Heparin; D013300:Streptokinase
Analiza powikłań ogólnych i krwotocznych po leczeniu ostrej, proksymalnej zakrzepicy zył głebokich kończyn dolnych antykoagulantami, streptokinaza lub trombektomia.