title: [Botox in combined treatment of cerebral palsy in children].
abstract: Ten patients with cerebral palsy (CP) were treated with botox (botulinum toxin, type A). The next forms of the disease were observed in the patients: a spastic dysplegia, a spastic hemiplegia, a spastic-hyperkinetic form of CP. Botox was injected into the damaged muscles in a dose of 100-300 Units. Therapeutical effect was found in 90% of the patients, an average duration of the medical effect was 6-12 months. Because of the small cohort of the patients treated with botox there was made a preliminary conclusion about the high efficiency and safety of botox for CP treatment. The need of further clinical observations was emphasized.
authors.forename: L V
authors.initials: LV
authors.lastname: Kalinina
authors.forename: E G
authors.initials: EG
authors.lastname: Sologubov
authors.forename: V M
authors.initials: VM
authors.lastname: Luzinovich
authors.forename: E M
authors.initials: EM
authors.lastname: Dutikova
mesh_terms: D000293:Adolescent; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000627:therapeutic use*; D002547:Cerebral Palsy / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular; D008297:Male; D009465:Neuromuscular Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D026741:Physical Therapy Modalities; D016896:Treatment Outcome
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A
vernacular_title: Botoks v kompleksnom lechenii detskogo tserebral'nogo paralicha.