Chemokines and chemokine receptors: disease targets for therapeutic development. November 15-16, 1999, McLean, VA, USA.
About a decade after discovery of IL-8, the first designated member of the protein family of chemotactic cytokines, about 50 of these so called 'chemokines' and about 15 receptors have been discovered in humans. Experimental as well as clinical data have identified many of the players in this network to be associated with various pathological phenomena. This conference discussed how research is closing in on chemokines as therapeutic targets as well as how chemokine functions might be exploited to design useful therapeutic tools.
Ehlert
J E
JE
University of Michigan, Department of Internal Medicine, Ann Arbor, MI, USA. jehlert@umich.edu
D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D018925:Chemokines / Q000502:physiology*; D015195:Drug Design; D006801:Humans; D019707:Receptors, Chemokine / Q000502:physiology*
D000911:Antibodies, Monoclonal; D018925:Chemokines; D019707:Receptors, Chemokine