title: Efficacy of amphotericin B colloidal dispersion in the treatment of Mediterranean visceral leishmaniasis in immunocompetent adult patients.
abstract: Twelve immunocompetent adults with Mediterranean visceral leishmaniasis (VL) were treated with amphotericin B colloidal dispersion (ABCD; 2 mg/kg/d for 7 d). All patients showed rapid clinical response without significant adverse events. Two weeks after therapy they were parasitologically cured and no relapses occurred during 6 months. ABCD is a valid alternative in the management of Mediterranean VL in adult patients.
authors.affiliation: Dipartimento di Malattie Infettive, Seconda Università, Naples, Italy.
authors.forename: G B
authors.initials: GB
authors.lastname: Gaeta
authors.forename: A
authors.initials: A
authors.lastname: Maisto
authors.forename: D
authors.initials: D
authors.lastname: Di Caprio
authors.forename: A
authors.initials: A
authors.lastname: Scalone
authors.forename: G
authors.initials: G
authors.lastname: Pasquale
authors.forename: F M
authors.initials: FM
authors.lastname: Felaco
authors.forename: D
authors.initials: D
authors.lastname: Galante
authors.forename: L
authors.initials: L
authors.lastname: Gradoni
mesh_terms: D000328:Adult; D000368:Aged; D000666:Amphotericin B / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D000981:Antiprotozoal Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007121:Immunocompetence; D007898:Leishmaniasis, Visceral / Q000188:drug therapy* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D000981:Antiprotozoal Agents; D000666:Amphotericin B