title: The LPD-II: a modified locked percutaneous device that permits safe subcutaneous access.
abstract: A locked percutaneous device, the LPD-I (previously described as LPD), is effective in overcoming the problems of skin downgrowth and local tissue infection; however, it can only be implanted at a site providing adequate subcutaneous adipose tissue to attach to the subcutaneous connector of the LPD-I. A modified device, the LPD-II, has been developed that has a thin dome and skin connector but does not have a subcutaneous tissue connector. In addition, a newly designed structure called the skin stop collar (SSC) has been developed. It is positioned just beneath the mesh collar described in the LPD-I to further improve the function of the LPD-II. Six rabbits were implanted with one LPD-II without the SSC (group 1) and five rabbits were implanted with one LPD-II with the SSC (group 2). For more than 6 months, two of the implants in group 1 rabbits were successful. Four of the implants in group 2 rabbits were successful for more than 1 year. One of the animals in group 2 died of causes unrelated to the device. We conclude the following: the mesh collar skin connector can function well as a locked percutaneous device without the subcutaneous tissue connector; the LPD-II can be implanted in any site and does not require the presence of subcutaneous adipose tissue; and the SSC may increase the success rate of LPD-II implantation provided the mesh collar is made of soft material.
authors.affiliation: Department of Pediatrics, East Carolina University Brody School of Medicine, Greenville, North Carolina, USA.
authors.forename: C
authors.initials: C
authors.lastname: Yu
authors.forename: G D
authors.initials: GD
authors.lastname: Harris
mesh_terms: D000273:Adipose Tissue / Q000166:cytology*; D000279:Administration, Cutaneous; D000818:Animals; D008422:Materials Testing; D019736:Prostheses and Implants; D011817:Rabbits; D012867:Skin / Q000166:cytology* / Q000254:growth & development; D014945:Wound Healing