[Radiation-induced glioblastoma and myxoma after treatment for undifferentiated carcinoma of the naspharynx].
Radio-induced tumor have been known for a long time to occur after treatment of cancer during childhood. This entity is exceptional following radiotherapy of the cavum. Skull and facial osteosarcoma were described after treatment of UCNT. We report two observations of radio-induced tumors arising, respectively three and seven years after treatment of UCNT. The first one is a temporoparietal glioblastoma and the second is a rhino- and pharyngeal myxoma. The two patients are alive after treatment of the second tumor. The delay of appearance of these tumors, their situation in the field's irradiated and dose received suggests their radio-induced nature. However, the cytogenetic study is necessary to confirm the implication of radiotherapy in the genesis of these cancers.
Daoud
J
J
Service de carcinologie-radiothérapie, CHU Habib-Bourguiba, Sfax, Tunisie.
Ben Salah
H
H
Kammoun
W
W
Ghorbel
A
A
Frikha
M
M
Jlidi
R
R
Besbes
M
M
Drira
M M
MM
Maalej
M
M
D000328:Adult; D001932:Brain Neoplasms / Q000209:etiology* / Q000473:pathology; D002277:Carcinoma / Q000532:radiotherapy*; D005260:Female; D005909:Glioblastoma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009232:Myxoma / Q000209:etiology* / Q000473:pathology; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy*; D009381:Neoplasms, Radiation-Induced
Glioblastome et myxome radio-induits après traitement d'un carcinome indiffencié du nasopharynx.