title: Good's syndrome presenting with cytomegalovirus pneumonia.
abstract: A 61-year-old woman who had undergone an operation for thymoma 17 years previously suddenly became dyspneic and showed bilateral pulmonary infiltrates on a chest radiograph. In the bronchoalveolar lavage fluid cells contained characteristic cytomegalic inclusion bodies, as well as cytomegalovirus DNA demonstrated by a polymerase chain reaction. Immunological findings included hypogammaglobulinemia, deficient numbers of circulating B cells, and impaired blast transformation of peripheral blood T cells in response to mitogens in vitro. Considering all of the findings, the patient was diagnosed with Good's syndrome presenting with cytomegalovirus pneumonia.
authors.affiliation: First Department of Internal Medicine, Kurume University School of Medicine.
authors.forename: S
authors.initials: S
authors.lastname: Ide
authors.forename: T
authors.initials: T
authors.lastname: Koga
authors.forename: T
authors.initials: T
authors.lastname: Rikimaru
authors.forename: Y
authors.initials: Y
authors.lastname: Katsuki
authors.forename: K
authors.initials: K
authors.lastname: Oizumi
mesh_terms: D000361:Agammaglobulinemia / Q000150:complications* / Q000175:diagnosis; D000917:Antibody Formation; D001402:B-Lymphocytes; D003586:Cytomegalovirus Infections / Q000209:etiology*; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D018655:Lymphocyte Count; D008875:Middle Aged; D011024:Pneumonia, Viral / Q000209:etiology*; D011183:Postoperative Complications / Q000276:immunology; D011239:Prednisolone / Q000009:adverse effects / Q000627:therapeutic use; D011658:Pulmonary Fibrosis / Q000209:etiology; D013577:Syndrome; D013945:Thymoma / Q000150:complications* / Q000276:immunology / Q000601:surgery; D013953:Thymus Neoplasms / Q000150:complications* / Q000276:immunology / Q000601:surgery
chemical_list: D007166:Immunosuppressive Agents; D011239:Prednisolone