title: Anaphylactic shock during endodontic treatment due to allergy to formaldehyde in a root canal sealant.
abstract: A 41-yr-old patient experienced an anaphylactic shock reaction caused by formaldehyde in a root canal sealant during endodontic treatment. The clinical events, positive skin tests, and a high level of immunoglobin E to formalin RAST (class 4) suggest the involvement of immunoglobin E-dependent mechanisms toward formaldehyde. This very infrequent observation in endodontic therapy focuses attention on the different pathological manifestations related to formalin, their mechanisms, and the prevention possibilities in dentistry.
authors.affiliation: Dental Faculty, University Louis Pasteur, Strasbourg, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Haïkel
authors.forename: J J
authors.initials: JJ
authors.lastname: Braun
authors.forename: H
authors.initials: H
authors.lastname: Zana
authors.forename: A
authors.initials: A
authors.lastname: Boukari
authors.forename: F
authors.initials: F
authors.lastname: de Blay
authors.forename: G
authors.initials: G
authors.lastname: Pauli
mesh_terms: D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000150:complications; D005557:Formaldehyde / Q000009:adverse effects*; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D008297:Male; D011108:Polymers / Q000009:adverse effects; D012118:Resorcinols / Q000009:adverse effects; D012387:Root Canal Filling Materials / Q000009:adverse effects* / Q000737:chemistry; D012882:Skin Tests
chemical_list: D011108:Polymers; D012118:Resorcinols; D012387:Root Canal Filling Materials; D005557:Formaldehyde; D007073:Immunoglobulin E; C032784:SPAD