title: [Production and characterization of an atenolol-reticulated povodone tablet].
abstract: The production of polymeric complexes in many active drugs with reticulated povidone increased dissolved component percentage. In this work made use a coevaporation technique. Complex formation has been tested by X Ray Diffractometry and Differential Scanning Calorimetry. The percentage of dissolution was determined to the USP XXIII Edition methodology. As can be seen from the results, the Atenolol-reticulated Povidone complexes has greater solubility than the Atenolol mixed with Lactose as excipient.
authors.affiliation: Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Tecnología Farmacéutica, Junín 956, Piso 6o, (1113) Buenos Aires, Argentina.
authors.forename: J
authors.initials: J
authors.lastname: Dobrecky
authors.forename: C
authors.initials: C
authors.lastname: Bregni
authors.forename: M C
authors.initials: MC
authors.lastname: Lamas
authors.forename: G
authors.initials: G
authors.lastname: Cancelo
authors.forename: S M
authors.initials: SM
authors.lastname: Estévez
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000737:chemistry*; D001262:Atenolol / Q000008:administration & dosage / Q000737:chemistry*; D002152:Calorimetry, Differential Scanning; D004339:Drug Compounding; D010592:Pharmaceutic Aids; D011205:Povidone / Q000737:chemistry*; D012995:Solubility; D014961:X-Ray Diffraction
chemical_list: D000319:Adrenergic beta-Antagonists; D010592:Pharmaceutic Aids; D001262:Atenolol; D011205:Povidone
vernacular_title: Obtención y caracterización de un complejo de atenolol con povidona reticulada.