title: Radiation therapy for extensive actinic keratosis.
abstract: Actinic keratosis in the most common premalignant keratotic tumour of sun-exposed skin. A 66-year-old man developed a large actinic keratosis on his scalp, which did not respond to conventional treatment. Fractionated radiotherapy with a cumulative dose of 28 Gy resulted in complete remission without relapse during a 14-month follow-up. In older subjects in whom conventional treatment fails, low-dose fractionated radiation therapy is an effective alternative method.
authors.affiliation: Department of Dermatology and Allergology, Friedrich-Schiller-University of Jena, Germany. barta@derma.uni-jena.de
authors.forename: U
authors.initials: U
authors.lastname: Barta
authors.forename: T
authors.initials: T
authors.lastname: Gräfe
authors.forename: U
authors.initials: U
authors.lastname: Wollina
mesh_terms: D000368:Aged; D019583:Dose Fractionation, Radiation; D006801:Humans; D007642:Keratosis / Q000209:etiology / Q000532:radiotherapy*; D008297:Male; D012535:Scalp; D013472:Sunlight / Q000009:adverse effects