title: [Anomalties of the interatrial septum and latent atrial vulnerability in unexplained ischemic stroke in young adults].
abstract: Seventy-four consecutive patients (18 to 55 years) underwent programmed atrial stimulation in the investigation of unexplained ischaemic stroke after a full work-up including transoesophageal echocardiography to exclude abnormalities of the interatrial septum (patent foramen ovale and/or atrial septal aneurysm). The parameters recorded during atrial electrophysiological investigation were: the effective atrial refractory period, loco-regional intra-atrial conduction, the index of latent atrial vulnerability and the inducibility by the extrastimulus technique. Seventy five per cent of patients with a patent foramen ovale and/or an atrial septal aneurysm were inducible compared with only 38% of patients with normal interatrial septa on transoesophageal echocardiography (p = 0.001). Fifty two per cent of patients with an anomaly of the atrial septum had latent atrial vulnerability compared with 26% of those with normal transoesophageal echocardiography (p = 0.02). These results confirm the relationship between atrial septal anomalies and latent atrial vulnerability in unexplained ischaemic stroke of young adults.
authors.affiliation: Service de cardiologie B, CHU Purpan, place du Docteur-Baylac, 31059 Toulouse.
authors.forename: E
authors.initials: E
authors.lastname: Somody
authors.forename: J F
authors.initials: JF
authors.lastname: Albucher
authors.forename: G
authors.initials: G
authors.lastname: Casteignau
authors.forename: N
authors.initials: N
authors.lastname: Prouteau
authors.forename: A
authors.initials: A
authors.lastname: Danielli
authors.forename: M
authors.initials: M
authors.lastname: Delay
authors.forename: F
authors.initials: F
authors.lastname: Chollet
authors.forename: J
authors.initials: J
authors.lastname: Puel
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002545:Brain Ischemia / Q000209:etiology*; D004594:Electrophysiology; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D020521:Stroke / Q000209:etiology*
vernacular_title: Anomalies du septum interauriculaire et vulnérabilité auriculaire latente dans l'accident vasculaire cérébral ischémique inexpliqué du sujet jeune.