The homocamptothecin, BN 80927, is a potent topoisomerase I poison and topoisomerase II catalytic inhibitor.
Demarquay
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Institut Henri Beaufour, 5 avenue du Canada, 91966 Les Ulis, France. daniele.demarquay@beaufour-ipsen.com
Coulomb
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H
Huchet
M
M
Lesueur-Ginot
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L
Camara
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J
Lavergne
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Bigg
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D
D000970:Antineoplastic Agents / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D002166:Camptothecin / Q000031:analogs & derivatives* / Q000494:pharmacology*; D002384:Catalysis / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005047:Etoposide / Q000494:pharmacology; D006801:Humans; D000077146:Irinotecan; D019384:Nucleic Acid Synthesis Inhibitors / Q000494:pharmacology; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors
D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; C121907:BN 80927; D004791:Enzyme Inhibitors; D019384:Nucleic Acid Synthesis Inhibitors; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; D005047:Etoposide; D000077146:Irinotecan; D002166:Camptothecin