Experimental evaluation of the safety and biocompatibility of a new antireflux prosthesis.
Previous studies have shown that encircling of the esophagogastric junction by a semiabsorbable scarf effectively prevents gastroesophageal reflux. The present study was performed to assess the long-term safety and biocompatibility of this type of scarf. The semiabsorbable scarf was implanted into 20 dogs either laparoscopically or via laparotomy. Pre- and post-operatively, contrast radiography, esophageal manometry, and upper gastrointestinal endoscopy were performed. No cases of perforation, stricture formation or other adverse effects were found after 1 and 2 years. It is concluded that the new type of scarf is without any adverse side-effects. Functional evaluation in reflux patients appears to be warranted.
Feussner
H
H
Ethicon GmbH & Co. KG, Norderstedt, Germany. feussner@nt1.chir.med.tu-muenchen.de
Bonavina
L
L
Collard
J M
JM
Holste
J
J
Freys
S
S
Horváth
O P
OP
Rüdiger
T
T
Stein
H J
HJ
Fuchs
K H
KH
D000818:Animals; D001672:Biocompatible Materials; D004285:Dogs; D005764:Gastroesophageal Reflux / Q000517:prevention & control*; D008365:Manometry; D019736:Prostheses and Implants
D001672:Biocompatible Materials