title: On the pathogenesis of perforin defects and related immunodeficiencies.
authors.forename: L
authors.initials: L
authors.lastname: Moretta
authors.forename: A
authors.initials: A
authors.lastname: Moretta
authors.forename: H
authors.initials: H
authors.lastname: Hengartner
authors.forename: R M
authors.initials: RM
authors.lastname: Zinkernagel
mesh_terms: D015616:Histiocytosis, Non-Langerhans-Cell / Q000209:etiology / Q000276:immunology; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000209:etiology* / Q000276:immunology; D008213:Lymphocyte Activation; D008562:Membrane Glycoproteins / Q000172:deficiency* / Q000276:immunology; D054353:Perforin; D052899:Pore Forming Cytotoxic Proteins; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology
chemical_list: D008562:Membrane Glycoproteins; D052899:Pore Forming Cytotoxic Proteins; D054353:Perforin