title: Progressive gastrointestinal histoplasmosis leading to colonic obstruction two years after initial presentation.
abstract: A 37-yr-old man from Ecuador presented with abdominal pain, diarrhea, and weight loss. Endoscopy revealed duodenal histoplasmosis. The patient improved with antifungal therapy but was readmitted 2 yr later with diarrhea and fever. Colonoscopy revealed histoplasmosis lesions, including a constricting transverse colon lesion. The patient refused surgery and died of colonic perforation. We discuss the diagnosis and management of gastrointestinal histoplasmosis in this report.
authors.affiliation: Division of Gastroenterology, Our Lady of Mercy Medical Center, New York Medical College, Bronx 10466, USA.
authors.forename: H
authors.initials: H
authors.lastname: Hertan
authors.forename: S
authors.initials: S
authors.lastname: Nair
authors.forename: P
authors.initials: P
authors.lastname: Arguello
mesh_terms: D000328:Adult; D003108:Colonic Diseases / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D003113:Colonoscopy; D018450:Disease Progression; D017809:Fatal Outcome; D005767:Gastrointestinal Diseases / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D006660:Histoplasmosis / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007415:Intestinal Obstruction / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D007416:Intestinal Perforation / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D008297:Male; D016312:Treatment Refusal