title: Experimental evaluation of the safety and biocompatibility of a new antireflux prosthesis.
abstract: Previous studies have shown that encircling of the esophagogastric junction by a semiabsorbable scarf effectively prevents gastroesophageal reflux. The present study was performed to assess the long-term safety and biocompatibility of this type of scarf. The semiabsorbable scarf was implanted into 20 dogs either laparoscopically or via laparotomy. Pre- and post-operatively, contrast radiography, esophageal manometry, and upper gastrointestinal endoscopy were performed. No cases of perforation, stricture formation or other adverse effects were found after 1 and 2 years. It is concluded that the new type of scarf is without any adverse side-effects. Functional evaluation in reflux patients appears to be warranted.
authors.affiliation: Ethicon GmbH & Co. KG, Norderstedt, Germany. feussner@nt1.chir.med.tu-muenchen.de
authors.forename: H
authors.initials: H
authors.lastname: Feussner
authors.forename: L
authors.initials: L
authors.lastname: Bonavina
authors.forename: J M
authors.initials: JM
authors.lastname: Collard
authors.forename: J
authors.initials: J
authors.lastname: Holste
authors.forename: S
authors.initials: S
authors.lastname: Freys
authors.forename: O P
authors.initials: OP
authors.lastname: Horváth
authors.forename: T
authors.initials: T
authors.lastname: Rüdiger
authors.forename: H J
authors.initials: HJ
authors.lastname: Stein
authors.forename: K H
authors.initials: KH
authors.lastname: Fuchs
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D004285:Dogs; D005764:Gastroesophageal Reflux / Q000517:prevention & control*; D008365:Manometry; D019736:Prostheses and Implants
chemical_list: D001672:Biocompatible Materials