title: Does successful embolization of endoleaks lead to aneurysm sac shrinkage?
abstract: OBJECTIVE
  To determine whether embolization of endoleaks after endovascular repair of aortic aneurysms is associated with a decrease in the diameter of the aneurysm.
  
  
  METHODS
  Fifteen patients (13 men; median age 76 years) demonstrated primary endoleaks persisting > or =3 months after endovascular abdominal aortic aneurysm repair with a variety of commercial endografts. In 8 patients, coil embolization failed to completely obliterate the leak, whereas embolotherapy proved successful in the remaining 7 patients. Surveillance of endoleaks and the effect of their embolization on aneurysm size were followed with serial computed tomographic (CT) scans. Follow-up after embolization extended for at least 12 months.
  
  
  RESULTS
  Patients with persistent leak exhibited a slight increase in mean aneurysm area from 21.41+/-4.25 to 22.47+/-6.70 cm2. Medians differed from 20.03 (range 16.59-28.73) to 23.03 (range 14.14-33.69) cm2 (p = 0.0078, 95% confidence interval [CI] = 0.0075 to 0.0081). Successfully treated patients, however, showed a mean decrease from 20.58+/-3.63 (median 19.87) to 16.36+/-6.46 cm2 (median 18.10) at 1 year (p = 0.0156, 95% CI = 0.0151 to 0.0160). The medians differed significantly between groups (p < 0.05).
  
  
  CONCLUSIONS
  Persistent endoleaks after endovascular aortic aneurysm treatment led to an increase in the diameter of the aneurysm, whereas complete occlusion was associated with a significant decrease in aneurysm diameter.
authors.affiliation: Departments of Radiology, University of Ulm, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Ermis
authors.forename: S
authors.initials: S
authors.lastname: Krämer
authors.forename: R
authors.initials: R
authors.lastname: Tomczak
authors.forename: R
authors.initials: R
authors.lastname: Pamler
authors.forename: O
authors.initials: O
authors.lastname: Kolokythas
authors.forename: A
authors.initials: A
authors.lastname: Schütz
authors.forename: C
authors.initials: C
authors.lastname: Wisianowsky
authors.forename: X
authors.initials: X
authors.lastname: Kapfer
authors.forename: J
authors.initials: J
authors.lastname: Görich
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000601:surgery*; D001027:Aortography; D019917:Blood Vessel Prosthesis Implantation; D004621:Embolization, Therapeutic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000628:therapy*; D011475:Prosthesis Failure; D014057:Tomography, X-Ray Computed