title: [Nociceptive system response to repetitive painful stimuli during chronic psychoemotional stress in humans].
abstract: Repeated nocigenic stimuli applied to the skin evoked a hyperalgesia in healthy subjects while in patients with neurasthenia which is a natural model of a chronic psychoemotional stress, they evoked a hyperalgesia accompanied by sensitization. The differences in the nociceptive system responses show particularities in reactivity (plasticity) of a wide dynamic range of the spinal neurons under chronic psychoemotional stress that is due to disorders in supraspinal descending modulation system of plasticity in the spinal nociceptive neurons.
authors.affiliation: I. P. Pavlov Institute of Physiology, Russian Acad. Sci., 199034, St. Petersburg, Nab. Makarova, 6, Russia.
authors.forename: I Ia
authors.initials: IIa
authors.lastname: Ashkinazi
authors.forename: E A
authors.initials: EA
authors.lastname: Vershinina
mesh_terms: D000328:Adult; D002908:Chronic Disease; D006801:Humans; D008297:Male; D009440:Neurasthenia / Q000503:physiopathology* / Q000523:psychology; D010146:Pain / Q000503:physiopathology*; D010147:Pain Measurement; D017288:Pain Threshold; D010812:Physical Stimulation; D012867:Skin / Q000503:physiopathology; D013315:Stress, Psychological / Q000503:physiopathology* / Q000523:psychology; D014465:Ultrasonics
vernacular_title: Osobennosti reagirovaniia sistemy nosiseptsii na povtornoe notsigennoe vozdeĭstvie pri khronicheskom psikhoémotsional'nom stresse u cheloveka.