Cardiac and great vessel thrombosis in Behçet's disease.
Behçet's disease (BD) is a chronic relapsing systemic vasculitis in which orogenital ulceration is a prominent feature. The disease affects many systems and causes hypercoagulability. We present a 27-year-old male patient who exhibited widespread great vessel thrombosis including right atrial and ventricular thrombi in the setting of right-sided infectious endocarditis and orogenital aphthous ulcerations and erythema nodosum due to BD. We reviewed the enigmatic prothrombotic state of BD, and discuss our prior experiences in this field.
Ozatli
D
D
Hacettepe University Medical School, Department of Haematology, Ankara, Turkey.
Kav
T
T
Haznedaroglu
I C
IC
Büyükaşik
Y
Y
Koşar
A
A
Ozcebe
O
O
Dündar
S V
SV
D000328:Adult; D000900:Anti-Bacterial Agents; D000925:Anticoagulants / Q000627:therapeutic use; D001367:Axillary Vein / Q000473:pathology*; D001528:Behcet Syndrome / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000150:complications; D004730:Endothelium, Vascular / Q000473:pathology; D004893:Erythema Nodosum / Q000209:etiology; D006325:Heart Atria; D006331:Heart Diseases / Q000209:etiology*; D006352:Heart Ventricles; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011667:Pulmonary Veins / Q000473:pathology*; D013281:Stomatitis, Aphthous / Q000188:drug therapy / Q000209:etiology; D013300:Streptokinase / Q000627:therapeutic use; D013479:Superior Vena Cava Syndrome / Q000209:etiology; D017131:Thrombectomy; D015912:Thrombolytic Therapy; D019851:Thrombophilia / Q000188:drug therapy / Q000209:etiology; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D014261:Tricuspid Valve; D020246:Venous Thrombosis / Q000209:etiology / Q000601:surgery; D014859:Warfarin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D000925:Anticoagulants; D014859:Warfarin; D006493:Heparin; D013300:Streptokinase; D010959:Tissue Plasminogen Activator