Analysis of VIP and CGRP plasma levels after radiotherapy for treatment of metastasis from prostatic carcinoma.
It has previously been shown that radiotherapy leads to an increased level of neuropeptides in various organs. In the study we report here, we examined whether the plasma levels of two neuropeptides, vasoactive intestinal peptide (VIP) and calcitonin gene-related peptide (CGRP), are influenced by radiotherapy. Blood was collected at four time intervals after radiotherapy; 1-12 days after treatment for skeletal metastasis from prostatic carcinoma. The VIP- and CGRP-plasma levels, as analyzed by radioimmunoassay, were not statistically different between the different time points analyzed.
Forsgren
S
S
Department of Integrative Medical Biology, Section for Anatomy, Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden. sture.forsgren@anatomy.umu.se
Landström
F
F
Kjörell
U
U
Henriksson
R
R
Franzén
L
L
D001859:Bone Neoplasms / Q000097:blood / Q000532:radiotherapy / Q000556:secondary; D015740:Calcitonin Gene-Related Peptide / Q000097:blood*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000097:blood* / Q000532:radiotherapy*; D013997:Time Factors; D014660:Vasoactive Intestinal Peptide / Q000097:blood*
D014660:Vasoactive Intestinal Peptide; D015740:Calcitonin Gene-Related Peptide