Angiomyxolipoma shares cytogenetic changes with lipoma, spindle cell/pleomorphic lipoma and myxoma.
Angiomyxolipoma is a rare variant of lipoma, two cases of which have recently been described. We report on the hitherto unreported clonal chromosomal changes of a third case of angiomyxolipoma. The karyotype showed a 46,XX,t(7;13)(p15;q14),t(8;12)(q13;p13)[17]/46,XX[3]. The involvement of 13q14, 12p13, and 8q13 supports a relationship with other types of benign lipomatous and myxoid tumors.
Sciot
R
R
University Hospital St-Raphael, Department of Pathology, Katholieke Universiteit Leuven, Belgium. Raf.Sciot@uz.kuleuven.ac.be
Debiec-Rychter
M
M
De Wever
I
I
Hagemeijer
A
A
D018207:Angiomyolipoma / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D018952:Antigens, CD34 / Q000032:analysis; D002869:Chromosome Aberrations; D002881:Chromosomes, Human, Pair 12; D002882:Chromosomes, Human, Pair 13; D002897:Chromosomes, Human, Pair 7; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007621:Karyotyping; D008067:Lipoma / Q000235:genetics*; D008875:Middle Aged; D009232:Myxoma / Q000235:genetics*; D014057:Tomography, X-Ray Computed; D014178:Translocation, Genetic; D014463:Ultrasonography
D018952:Antigens, CD34