title: Cytoplasmic presenilin aggregates in proteasome inhibitor-treated cells.
authors.affiliation: Genetics and Aging Unit and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Ingano
authors.forename: K M
authors.initials: KM
authors.lastname: Lentini
authors.forename: I
authors.initials: I
authors.lastname: Kovacs
authors.forename: R E
authors.initials: RE
authors.lastname: Tanzi
authors.forename: D M
authors.initials: DM
authors.lastname: Kovacs
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D000544:Alzheimer Disease / Q000473:pathology; D000818:Animals; D001921:Brain / Q000473:pathology; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D006801:Humans; D008565:Membrane Proteins / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure; D009097:Multienzyme Complexes / Q000378:metabolism*; D016874:Neurofibrillary Tangles / Q000473:pathology; D053764:Presenilin-1; D011480:Protease Inhibitors / Q000494:pharmacology*; D046988:Proteasome Endopeptidase Complex; D011994:Recombinant Proteins / Q000378:metabolism / Q000648:ultrastructure; D014162:Transfection
chemical_list: D008565:Membrane Proteins; D009097:Multienzyme Complexes; C508853:PSEN1 protein, human; D053764:Presenilin-1; D011480:Protease Inhibitors; D011994:Recombinant Proteins; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex; D000251:Adenosine Triphosphatases