[Urokinase does not effect the tissue factor mediated monocyte pro-coagulant activity].
Both spontaneous and endotoxin-induced tissue factor expressions were not altered by exogenous urokinase. Inhibition of endogenous urokinase and plasmin did not affect the endotoxin-induced monocyte tissue factor's activity.
Aref'eva
T I
TI
Russian Research Cardiological Complex, 121552, 3rd Cherepkovskaya St., 15a, Moscow, Russia.
Krasnikova
T L
TL
D001665:Binding Sites; D001777:Blood Coagulation; D002462:Cell Membrane / Q000378:metabolism; D002478:Cells, Cultured; D005341:Fibrinolysin / Q000378:metabolism; D006801:Humans; D008070:Lipopolysaccharides / Q000494:pharmacology; D009000:Monocytes / Q000378:metabolism / Q000502:physiology*; D011956:Receptors, Cell Surface / Q000378:metabolism; D055293:Receptors, Urokinase Plasminogen Activator; D013925:Thromboplastin / Q000378:metabolism*; D014568:Urokinase-Type Plasminogen Activator / Q000378:metabolism* / Q000494:pharmacology
D008070:Lipopolysaccharides; C524898:PLAUR protein, human; D011956:Receptors, Cell Surface; D055293:Receptors, Urokinase Plasminogen Activator; D013925:Thromboplastin; D005341:Fibrinolysin; D014568:Urokinase-Type Plasminogen Activator
Urokinaza ne vliiaet na oposredovannuiu tkanevym faktorom prokoaguliatsionnuiu aktivnost' monotsitov.