title: Coronary artery bypass graft outcome: the Trinidad and Tobago experience.
abstract: The study is retrospective review of the demographic, clinical, angiographic, and operative data of the first 205 consecutive CABG operations performed by Caribbean Heart Care at the Eric Williams Medical Sciences Complex (EWMSC), Trinidad and Tobago, between November 1993 and December 1997. The aim of the study was to determine the in-hospital and intermediate-term follow-up results. The mean age of patients was 59 +/- 10 years and 78% were male. Sixty-four per cent were of East Indian descent, whereas 16% were of African descent. Forty-eight per cent of the patients were hypertensive, 46% were diabetic, 33% had hyperlipidaemia, 20% had a recent history of cigarette smoking and 16% were obese. Sixty-five per cent had a positive family history of ischaemic heart disease. The average time interval between angiography and surgery was 2.3 months. At the time of angiography, 63.5% of patients had Canadian Cardiac Society (CCS) class 3 or 4 angina. The mean ejection fraction was 61 +/- 15%. Wall motion abnormalities were seen in 67% of patients. Significant stenoses of the left anterior descending artery, right circumflex artery, circumflex and ramus coronary arteries were present in 91%, 78%, 54% and 5%, respectively. Many patients (67%) had severe diffuse disease on angiography. The mean intensive care stay was 2.2 +/- 0.8 days. In-hospital mortality was 3.9% (8/205). The most frequent post-operative complication was haemorrhage (2.6%). Acute renal failure occurred in 2.1%; pulmonary collapse, 1.6%; stroke, 1% and cardiac arrest, 1%. Both sternal wound infections and systemic sepsis occurred in 0.5%. Intermediate-term follow-up data were obtained for 92% (189/205). The duration of follow-up ranged from 1 to 5 years (mean 3.7 years). During the follow-up period, 7 patients (3.4%) died. Angina severity was reduced from a mean CCS score of 2.61 +/- 0.95 before CABG to 1.22 +/- 0.55 at the time of follow-up (p < 0.0001). Overall 4-year mortality compared favourably with data from international studies. Among survivors, quality of life improved as evidenced by the reduction in the mean angina score.
authors.affiliation: Cardiopulmonary Research Unit, Caribbean Heart Care and Eric Williams Medical Sciences Complex, University of the West Indies, St Augustine, Trinidad and Tobago.
authors.forename: C N
authors.initials: CN
authors.lastname: Thomas
authors.forename: S H
authors.initials: SH
authors.lastname: Brann
authors.forename: A R
authors.initials: AR
authors.lastname: Douglas
authors.forename: J M
authors.initials: JM
authors.lastname: Thomas
authors.forename: S C
authors.initials: SC
authors.lastname: Daniel
authors.forename: C
authors.initials: C
authors.lastname: Posthoff
authors.forename: K A
authors.initials: KA
authors.lastname: Rampersad
authors.forename: G D
authors.initials: GD
authors.lastname: Angelini
mesh_terms: D000787:Angina Pectoris / Q000145:classification / Q000601:surgery; D002315:Cardiopulmonary Bypass / Q000295:instrumentation; D017023:Coronary Angiography; D001026:Coronary Artery Bypass / Q000401:mortality / Q000706:statistics & numerical data*; D003327:Coronary Disease / Q000145:classification / Q000208:ethnology / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011788:Quality of Life; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D014300:Trinidad and Tobago / Q000453:epidemiology