Information processing in the spinocerebellar system.
The purpose of this study was to determine whether sensory information about limb kinematics relayed to the cerebellum over spinocerebellar pathways may be modified at the cerebellar level. We tested this by recording from dorsal spinocerebellar tract (DSCT) and Purkinje cells under the same experimental conditions in which the hindlimbs of anesthetized cats were passively moved through a series of step-like movement cycles. A population analysis of the response behavior showed that DSCT neurons encode a combination of limb axis position and movement velocity, whereas the Purkinje cells located in the DSCT cerebellar target areas encode limb axis velocity and position independently. We conclude from this that the cerebellum may somehow extract a velocity component from the afferent input signal.
Valle
M S
MS
Department of Neuroscience, University of Minnesota, Minneapolis 55455, USA.
Bosco
G
G
Poppele
R
R
D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001696:Biomechanical Phenomena; D002415:Cats; D005121:Extremities / Q000294:innervation / Q000502:physiology*; D005684:Gait / Q000502:physiology*; D008959:Models, Neurological; D009434:Neural Pathways / Q000502:physiology*; D011689:Purkinje Cells / Q000166:cytology / Q000502:physiology*; D012044:Regression Analysis; D013116:Spinal Cord / Q000166:cytology / Q000502:physiology*