title: Covalently bonded polysaccharide derivatives as chiral stationary phases in high-performance liquid chromatography.
abstract: Polysaccharide derivatives have been extensively used as chromatographic chiral selectors in chiral stationary phases (CSPs) for the separation of enantiomers by HPLC. When coated onto a silica matrix, they represent nowadays one of the most popular type of CSPs. However, they are only compatible with a limited choice of solvents. The main drawback of these CSPs is related to the solubility of the chiral selector in a number of solvents, which limits their applicability. The different attempts which have been described up to now to overcome this problem by covalently fixing the chiral selector to a matrix are reviewed in this paper.
authors.affiliation: Laboratori de Química Farmacèutica, Facultat de Farmàcia, Universitat de Barcelona, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Franco
authors.forename: A
authors.initials: A
authors.lastname: Senso
authors.forename: L
authors.initials: L
authors.lastname: Oliveros
authors.forename: C
authors.initials: C
authors.lastname: Minguillón
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation*; D011134:Polysaccharides / Q000737:chemistry*
chemical_list: D011134:Polysaccharides