[Structure and function of thyroid hormone receptors].
The new data concerning the structure of nuclear receptor of thyroid hormone and peculiarities of its functioning as a ligand-dependent transcriptional factor are reviewed. Considerable attention is concentrated on the analysis of mechanisms of receptor interactions with specifical DNA regions which mediate iodothyronine influence on the gene expression and factors that participate in regulation of these mechanisms.
Antoniak
G L
GL
Ignatenko
Iu V
IuV
Babich
N O
NO
Snitinskii
V V
VV
D000818:Animals; D002467:Cell Nucleus / Q000737:chemistry / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans; D008024:Ligands; D011988:Receptors, Thyroid Hormone / Q000737:chemistry* / Q000378:metabolism*; D013970:Thyronines / Q000378:metabolism; D014157:Transcription Factors / Q000737:chemistry* / Q000378:metabolism
D008024:Ligands; D011988:Receptors, Thyroid Hormone; D013970:Thyronines; D014157:Transcription Factors
Struktura i funktsii retseptorov tireoidn'ikh gormonov.