Biotransformation of diterpenes and diterpene derivatives by Beauveria bassiana ATCC 7159.
The biohydroxylation of stemodin and stemodinone by Beauveria bassiana ATCC 7159 gave exclusively 2alpha,13,18-trihydroxystemodane and 13,18-dihydroxystemodan-2-one respectively. Stemarin was converted to the novel 1beta,13,19-trihydroxystemarane and 13-hydroxystemarane-19-carboxylic acid. The synthesis and biotransformation of various derivatives of stemodin have also been studied.
Buchanan
G O
GO
Department of Chemistry, University of the West Indies, Mona, Jamaica.
Reese
P B
PB
D001203:Ascomycota / Q000378:metabolism*; D001711:Biotransformation; D004224:Diterpenes / Q000737:chemistry / Q000493:pharmacokinetics*; D013057:Spectrum Analysis
D004224:Diterpenes