Elongation factor 2 in the liver and skeletal muscle of mice is decreased by starvation.
We examined whether starvation affected the amount of EF-2 protein as well as the level of its mRNA in the liver and skeletal muscle of mice, to understand the molecular mechanism for nutritional adaptation of protein-turnover. Although the amount of EF-2 was diminished by starvation in each of the tissues examined, the amount of EF-2 mRNA did not decrease in parallel with the protein.
Yoshizawa
F
F
Department of Science of Living, Morioka Junior College, Iwate Prefectural University, Takizawa, Japan.
Miura
Y
Y
Tsurumaru
K
K
Kimata
Y
Y
Yagasaki
K
K
Funabiki
R
R
D000818:Animals; D008099:Liver / Q000378:metabolism*; D051379:Mice; D018482:Muscle, Skeletal / Q000378:metabolism*; D020652:Peptide Elongation Factor 2 / Q000235:genetics / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism; D013217:Starvation / Q000378:metabolism*
D020652:Peptide Elongation Factor 2; D012333:RNA, Messenger