title: A Robertsonian translocation, rob(2;28), found in Vietnamese cattle.
abstract: A new Robertsonian translocation, rob(2;28), was discovered in a local population of the Vietnamese Cattle. The animal (2n = 59, XY) was found by Q- and R-banding to be a heterozygous carrier of a centric fusion translocation involving chromosomes 2 and 28. FISH analysis using a bovine satellite I DNA probe demonstrated that the centromeric heterochromatin block of the rob(2;28) chromosome become much smaller than its ancestors suggesting a monocentric nature of this centric fusion. This is the first report identifying a Robertsonian translocation in Southeast Asian cattle by karyotyping of banded chromosomes.
authors.affiliation: Laboratory of Animal Genetics, Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Japan. kztana@agr.nagoya-u.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Amano
authors.forename: T
authors.initials: T
authors.lastname: Yamagata
authors.forename: V B
authors.initials: VB
authors.lastname: Dang
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuda
authors.forename: T
authors.initials: T
authors.lastname: Namikawa
mesh_terms: D000818:Animals; D002417:Cattle / Q000235:genetics*; D002503:Centromere; D002871:Chromosome Banding; D002875:Chromosomes / Q000235:genetics*; D004247:DNA / Q000032:analysis; D006570:Heterochromatin / Q000235:genetics; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008297:Male; D008677:Metaphase; D018895:Microsatellite Repeats; D014178:Translocation, Genetic; D014744:Vietnam
chemical_list: D006570:Heterochromatin; D004247:DNA