[Diagnosis of hemochromatosis with magnetic resonance].
Hemochromatosis is a disorder of parenchymal iron overload. The diagnosis is based upon clinical manifestations, laboratory findings and iron concentration in liver. Magnetic resonance imaging (MRI) shows a decrease in liver signal intensity. Its role has not been already defined. Nonetheless, ratio of liver to muscle proton density (LMPD) shows a significant correlation with hepatic iron. One patient with a long-standing cirrhosis with data of hemochromatosis whose coagulation study did not allow to perform a liver biopsy was diagnosed with this method. Hepatic iron concentration was calculated based upon: microgram/g of hepatic iron = (-5.174* LMPD) + 9.932. MRI can be useful in the evaluation of hemochromatosis among patients who refuse or have contraindication to liver biopsy.
Larrubia
J R
JR
Servicio de Aparato Digestivo, Hospital Universitario Clínico San Carlos, Universidad Complutense, Madrid.
Mendoza
J L
JL
Pérez de la Serna
J A
JA
Ruiz de León
A
A
Méndez
R
R
Díaz-Rubio
M
M
D000368:Aged; D006432:Hemochromatosis / Q000175:diagnosis*; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male
Diagnóstico de la hemocromatosis por resonancia magnética.