[Pathogenicity factors of Corynebacterium diphtheriae circulating in the Primorski region under conditions of mass immunization of population].
The study of the main pathogenicity factors of C. diphtheriae (adhesive activity, toxigenicity, detection of tox+ gene) circulating in the Primorski Territory has been made. As revealed in this study, at the period of declined epidemic process due to mass immunization of the adult and child population against diphtheria the selection of C. diphtheriae strains with weak toxigenicity and low adhesiveness was observed. No strains having tox+ genes have been detected among C. diphtheriae nontoxigenic strains circulating in the Primorski Territory.
Makarenkova
I D
ID
Research Institute of Epidemiology and Microbiology, Sanitary and Epidemiological Inspection Center of the Primorski Territory, Vladivostok, Russia.
Zaporozhets
T S
TS
Besednova
N N
NN
Khoroshevskaia
Iu N
IuN
Cherdantseva
G K
GK
D000328:Adult; D001422:Bacterial Adhesion; D002648:Child; D003353:Corynebacterium diphtheriae / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*; D004269:DNA, Bacterial / Q000032:analysis; D004165:Diphtheria / Q000382:microbiology* / Q000517:prevention & control; D004167:Diphtheria Toxin / Q000032:analysis / Q000235:genetics; D006801:Humans; D007114:Immunization; D016133:Polymerase Chain Reaction
D004269:DNA, Bacterial; D004167:Diphtheria Toxin
Faktory patogennosti Corynebacterium diphtheriae, tsirkuliruiushchikh v primorskom krae v usloviiakh massovoĭ immunizatsii naseleniia.