[Interaction of tumor cell differentiation induced in vitro and sensitivity of them to nonspecific lysis by natural killer cells. Possible mechanisms].
The literature data on the influence of a large group of cancer cell differentiation inducers on the modulation of their susceptibility to non-MHC-restricted lysis (non-specific cytotoxicity, NCT) by natural killer (NK) cells have been analysed. A possible association between the apoptogenic action of differentiation inducers and their ability to modulate the NCT of cell targets by NK cells is discussed.
Anisimov
A G
AG
Petrozavodsk State University.
Bolotnikov
I A
IA
Chekmasova
A A
AA
Volkova
T O
TO
D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D002454:Cell Differentiation / Q000187:drug effects / Q000276:immunology*; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D014407:Tumor Cells, Cultured
Vzaimosviaz' indutsirovannoĭ in vitro differentsirovki kletok opukholevykh liniĭ i chuvstvitel'nosti ikh k nespetsificheskomu lizisu estestvennymi killernymi kletkami. Vozmozhnye mekhanizmy.