LD-PACE II: a new cardiomyostimulator for cardiac bioassist.
The LD-PACE II was designed for use in cardiomyoplasty, aortomyoplasty, and skeletal muscle ventricles. All parameters specified as programmable can be changed in a noninvasive manner (using a programming interface wand connected to a computer using the Windows 95/98 environment). Two new functions may be very useful clinically, based on experimental research. 1. Work-rest regimen. The LD-PACE II is able to deliver alternating periods of muscle contractions and rest. Work and rest periods may be programmed independently between 1 and 120 minutes in increments of 1 minute. The work-rest regimen may be useful clinically if muscle contractions are needed for cardiac assist postoperatively. 2. Night/day regimen. This feature allows for a change in the ratio of muscle contractions according to a patient's activity level. During the day the cardiosynchronization ratio may be set from 1:1 to 1:4, and during the night it may be set for 1:8 to 1:16. This allows the muscle to have a long rest period, prevents overuse, and prolongs battery life. These two new features make this cardiomyostimulator very attractive for cardiomyoplasty in particular. The addition of the work-rest and night-day regimens allow the muscle to rest for periods during the day to prevent overuse, subsequent damage, and potential atrophy.
Chekanov
V S
VS
Milwaukee Heart Institute (Heart Care Associates), Wisconsin, USA.
Chachques
J C
JC
Brum
F
F
Arzuaga
J
J
Arzuaga
P
P
Krum
D P
DP
Hare
J W
JW
Maternowski
M A
MA
Tchekanov
G V
GV
Fiandra
O
O
Hammond
R
R
Melamed
V
V
Chiu
R C
RC
Stephenson
L W
LW
D018421:Cardiomyoplasty / Q000295:instrumentation*; D006321:Heart / Q000502:physiology*; D006353:Heart-Assist Devices; D006801:Humans; D009200:Myocardial Contraction; D010138:Pacemaker, Artificial; D011474:Prosthesis Design