Hepatic tumors in children.
Although they account for only 1% to 4% of solid tumors in children, hepatic tumors and pseudotumors offer a diagnostic challenge to the clinician seeing only an occasional case. Metastatic lesions such as neuroblastoma, Wilms' tumor, and lymphoma are the most common neoplasm seen in the liver, but 10 distinct primary tumors and pseudotumors of the liver occur with some regularity, and a few others may be seen rarely, including leiomyosarcoma, rhabdoid tumor, and endodermal sinus tumor. Five of these neoplasms--hepatoblastoma, infantile hemangio-endothelioma, mesenchymal hamartoma, undifferentiated embryonal sarcoma, and embryonal rhabdomyosarcoma of the biliary tree--occur only in children and are the major focus of the article.
Stocker
J T
JT
Department of Pathology, F. Edward Hebert School of Medicine, Uniformed Services, University of the Health Sciences, Bethesda, Maryland, USA.
D002648:Child; D006222:Hamartoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D006390:Hemangioendothelioma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D018197:Hepatoblastoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D012509:Sarcoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy