title: An in vitro study of fluoride release from a resin-modified glass ionomer cement after exposure to toothpaste slurries of different pH.
abstract: The aim of the study was to evaluate the fluoride release from an aged resin-modified glass ionomer (Vitremer) after exposure to five toothpaste slurries with different pH values. Cylindrical specimens of the material were leached in de-ionized water for 3 months and then exposed for 30 min daily for 10 days to three dentifrice slurries (20 specimens/group) containing 0.05% fluoride with pH values of 2.6, 5.7 and 8.3 and two non-fluoridated slurries with pH values of 2.5 and 5.7. A neutral NaF solution (0.05% F) was used as a control. During the 30 min exposure time, the fluoride concentration was gradually decreased in order to imitate the clinical situation. Thereafter, specimens were immersed individually in de-ionized water and the fluoride release determined. After the first day of exposure, all groups except one without fluoride (pH 5.7) showed significantly (P < 0.05) increased fluoride release. After exposure to the fluoridated toothpaste slurry with pH 5.7, significantly (P < 0.05) more fluoride was released compared to the toothpaste slurry with pH 8.3. Low pH (2.5 or 2.6) of the slurry resulted in a significantly (P < 0.05) higher fluoride release, regardless of whether it was fluoridated or not. The total amount of fluoride released after exposure to the more acidic fluoride toothpaste slurry was greater than that released from the more acidic non-fluoride toothpaste and the less acidic fluoride toothpaste. Our data indicate that the fluoride release from the resin-modified glass ionomer studied may be increased after treatment with an acidified NaF-toothpaste.
authors.affiliation: Department of Cariology, Faculty of Odontology, Göteborg University, Box 450, SE 405 30 Göteborg, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Olsson
authors.forename: C G
authors.initials: CG
authors.lastname: Emilson
authors.forename: D
authors.initials: D
authors.lastname: Birkhed
mesh_terms: D000704:Analysis of Variance; D002327:Cariostatic Agents / Q000737:chemistry*; D003188:Composite Resins / Q000737:chemistry*; D004347:Drug Interactions; D005899:Glass Ionomer Cements / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D017736:Ion-Selective Electrodes; D012969:Sodium Fluoride / Q000737:chemistry*; D018709:Statistics, Nonparametric; D013535:Suspensions; D013997:Time Factors; D014100:Toothpastes / Q000737:chemistry*
chemical_list: D002327:Cariostatic Agents; D003188:Composite Resins; D005899:Glass Ionomer Cements; D013535:Suspensions; D014100:Toothpastes; C084550:Vitremer; D012969:Sodium Fluoride