title: Management of toxic epidermal necrolysis.
abstract: Toxic epidermal necrolysis and Stevens-Johnson syndrome are rare, life-threatening drug reactions. Widespread epidermal necrosis and mucosal erosions lead to complications similar to those developing after extensive burns. Treatment is supportive. The role of steroids and other potential disease-modifying agents remains to be established by controlled studies.
authors.affiliation: Dermatology Centre, Hope Hospital, Salford, Manchester M6 8HD.
authors.forename: N M
authors.initials: NM
authors.lastname: Craven
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D004750:Enteral Nutrition; D005440:Fluid Therapy; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D011379:Prognosis; D013256:Steroids; D013262:Stevens-Johnson Syndrome / Q000209:etiology / Q000628:therapy*
chemical_list: D000893:Anti-Inflammatory Agents; D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents; D013256:Steroids