Polysaccharide-based chiral stationary phases for high-performance liquid chromatographic enantioseparation.
Recent developments of polysaccharide-based chiral stationary phases (CSPs) for the direct separation of enantiomers in high-performance liquid chromatography (HPLC) are mainly reviewed together with the results on mechanistic studies by means of chromatography, NMR and mass spectroscopies, and computational methods. Miscellaneous applications of polysaccharide derivatives to the newly developed, chiral dynamic high-performance liquid chromatography (DHPLC) for obtaining a nonracemic compound are also described.
Yashima
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Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University, Japan. yashima@apchem.nagoya-u.ac.jp
D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011134:Polysaccharides / Q000737:chemistry*; D013237:Stereoisomerism
D011134:Polysaccharides