title: Evaluating ambulatory urodynamics: a prospective study in asymptomatic women.
abstract: OBJECTIVE
  To identify abnormal detrusor contractions in asymptomatic women undergoing ambulatory urodynamics, to standardise the investigation technique for women with urinary symptoms for clinical practice.
  
  
  METHODS
  Prospective observational study.
  
  
  METHODS
  Two tertiary referral urogynaecology units: one in London, UK and one in Varese, Italy.
  
  
  METHODS
  Women without urinary symptoms were recruited into the study. Ambulatory urodynamics was performed according to the King's College Hospital protocol. All the traces were analysed in four different ways: 1. without the second bladder transducer measurements displayed on the screen and without the diary; 2. as in 1. but with the diary; 3. with the second bladder sensor displayed on the screen but without the diary; 4. as in 3. but with the diary. The diary was always interpreted at the end of the test with the woman present. For each method we reported the total number of detrusor contractions and whether the woman would have been diagnosed as having abnormal detrusor contraction. Cochran's Q test was used for statistical analysis.
  
  
  RESULTS
  Twenty-six women (mean age 31.7 years) were recruited. Ambulatory urodynamic testing lasted an average of 3.57 hour. The diagnosis of abnormal detrusor contraction varied by 65.4% depending on the method of analysis used. The diary and the women's symptoms during the test were the most discriminating factors. A significant difference between the diagnoses was obtained when comparing the four different ways of analysis. According to our protocol only three women (11.5%) had abnormal detrusor contractions.
  
  
  CONCLUSIONS
  Using our protocol almost 90% of asymptomatic women have a stable bladder on ambulatory urodynamics. This is similar to the results of labouratory urodynamic testing of asymptomatic women but is in contrast to previous reports of ambulatory urodynamics of asymptomatic women. The technique used during ambulatory urodynamics determines the tests ability to detect detrusor instability with an accurate symptom diary being the most important.
authors.affiliation: Department of Urogynaecology, King's College Hospital, London, UK.
authors.forename: S
authors.initials: S
authors.lastname: Salvatore
authors.forename: V
authors.initials: V
authors.lastname: Khullar
authors.forename: L
authors.initials: L
authors.lastname: Cardozo
authors.forename: K
authors.initials: K
authors.lastname: Anders
authors.forename: G
authors.initials: G
authors.lastname: Zocchi
authors.forename: M
authors.initials: M
authors.lastname: Soligo
mesh_terms: D000328:Adult; D000553:Ambulatory Care / Q000379:methods / Q000592:standards; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D009119:Muscle Contraction / Q000502:physiology; D011446:Prospective Studies; D001745:Urinary Bladder Diseases / Q000175:diagnosis* / Q000503:physiopathology; D014555:Urination Disorders / Q000175:diagnosis* / Q000503:physiopathology; D014563:Urodynamics