title: [Bentall-DeBono intervention: 8 years of clinical experience].
abstract: BACKGROUND
  Annulo-aortic ectasia is a dilation of the aortic root with the involvement of the Valsalva sinuses. In 1968 Bentall and DeBono proposed to replace the aortic valve, the Valsalva sinuses and the ascending aorta with a composite tube graft containing aortic valve prosthesis. Consequently coronary ostia had to be reimplanted on the prosthetic tube. Recently the use of new materials has resulted in a more acceptable operative risk, and postoperative bleeding and late mortality have been reduced.
  
  
  METHODS
  From January 1991 to December 1998, 44 out of 241 patients were operated on with the Bentall-DeBono procedure, affected by dissecting or expansive aneurysm of the ascending aorta. Of the 44 patients (35 males, 9 females, mean age 53.7 years), 3 presented with acute aortic dissection, 5 were asymptomatic, 10 were in NYHA functional class II, 14 in class III, 9 in class IV, and 2 in CCS class 4; 1 patient had dysphonia; 37 patients presented with isolated aortic regurgitation, and 7 associated aortic valvular stenosis. The diagnosis of acute dissection was made by transesophageal echocardiography and that of expansive aneurysm by thorax helical computed tomographic scanning and/or magnetic resonance imaging and cardiac catheterization. Follow-up was obtained in 100% of the patients for an average of 23 +/- 20.9 months (range 4-79 months).
  
  
  RESULTS
  Four patients (9%) died; in 4 patients (9%) postoperative bleeding needed reoperation, in 5 (11.4%) a permanent pacemaker for atrioventricular block was implanted, and 1 patient (2.3%) had transient hemiparesis. At univariate analysis predictive factors for operative risk were NYHA functional class IV (p < 0.005) and atherosclerotic etiology (p < 0.05). At follow-up 7 late deaths occurred for an actuarial survival at 24 months of 75 +/- 9%. Causes were sudden death in 3 patients, cardiac failure in 3 and stroke in 1 patient; 31 surviving patients (94%) were in NYHA functional class I and 2 patients in class II (6%).
  
  
  CONCLUSIONS
  The Bentall-DeBono procedure involves moderate risk with good results; clinical presentation and associated valvular pathology influence early and mid-term results.
authors.affiliation: Cattedra di Cardiochirurgia, Università degli Studi Tor Vergata, Roma.
authors.forename: A
authors.initials: A
authors.lastname: Scafuri
authors.forename: P
authors.initials: P
authors.lastname: Nardi
authors.forename: S
authors.initials: S
authors.lastname: Forlani
authors.forename: C
authors.initials: C
authors.lastname: Bassano
authors.forename: M D
authors.initials: MD
authors.lastname: Pierri
authors.forename: A
authors.initials: A
authors.lastname: Pellegrino
authors.forename: P
authors.initials: P
authors.lastname: Polisca
authors.forename: F
authors.initials: F
authors.lastname: Tomai
authors.forename: G M
authors.initials: GM
authors.lastname: De Matteis
authors.forename: L
authors.initials: L
authors.lastname: Chiariello
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000601:surgery*; D004108:Dilatation, Pathologic; D005260:Female; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000601:surgery; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D012189:Retrospective Studies; D013997:Time Factors
vernacular_title: Intervento di Bentall-DeBono: otto anni di esperienza clinica.