[Changes in the functional activity of neutrophils during their interaction with Yersinia pestis in vitro].
The functional state and electrochemical properties of human blood neutrophil leukocytes after their in vitro interaction with Y. pestis cells, strain EV, was analyzed. A considerable decrease in the electrophoretic mobility of neutrophil leukocytes and a considerable increase in their phagocytic indices was shown. At the same time the maximum phagocytic activity in the total pool of isolated neutrophil leukocytes was registered in fractions having higher electrophoretic mobility. The dependence of electrophoretic mobility on the state of neutrophil membranes, as well as the degree of their activation, is discussed.
Firstova
V V
VV
Research Institute for Plague Control Microbe, Saratov, Russia.
Stukova
N Iu
NIu
Ledvanov
M Iu
MIu
D002469:Cell Separation; D006801:Humans; D066298:In Vitro Techniques; D009504:Neutrophils / Q000276:immunology*; D010587:Phagocytosis; D015010:Yersinia pestis / Q000276:immunology*
Izmeneniia funktsional'noĭ aktivnosti neĭtrofil'nykh leĭkotsitov pri vzaimodeĭstvii s Yersinia pestic in vitro.