Disulfiram revisited.
Disulfiram can be important in helping motivated alcoholics to remain abstinent. Prescribers should be aware of disulfiram's toxicity, and how to recognize and manage reactions. A number of other agents are available to help alcoholics remain sober, although these do not necessarily obviate use of disulfiram. Also, disulfiram may have a wider role in the management of the addictions, e.g. in cocaine use.
O'Shea
B
B
Newcastle Hospital, Greystones, Co Wicklow, Republic of Ireland.
D000427:Alcohol Deterrents / Q000627:therapeutic use*; D000437:Alcoholism / Q000188:drug therapy*; D004221:Disulfiram / Q000627:therapeutic use*; D006801:Humans; D008111:Liver Function Tests / Q000379:methods*; D011605:Psychoses, Substance-Induced / Q000209:etiology; D016896:Treatment Outcome
D000427:Alcohol Deterrents; D004221:Disulfiram