[Effect of certain lectins on platelet aggregation in healthy people].
A study was made of the ability of some plant lectins, which bind specifically to different carbohydrate determinants of glycoproteins, to induce the platelet aggregation in healthy humans. It has been shown that phytohemagglutinin (PHA) and wheat germ agglutinin (MGA) induce a more marked platelet aggregation than concanvalin A (Con A). Lens culinaris agglutinin (LCA) had a slight aggregate activity. It was pointed at different roles played by carbohydrate determinants of platelet glycoproteins in fulfilling their aggregation function.
Kirichuk
V F
VF
Normal Human Physiology, State Medical University, Saratov.
Voskoboĭ
I V
IV
D050260:Carbohydrate Metabolism; D006801:Humans; D037102:Lectins / Q000494:pharmacology*; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects*; D010980:Platelet Membrane Glycoproteins / Q000737:chemistry / Q000378:metabolism; D012016:Reference Values
D037102:Lectins; D010980:Platelet Membrane Glycoproteins
Vliianie nekotorykh lektinov na agregatsiiu trombotsitov zdorovykh liudeĭ