4,5-Dihydroisoxazoles: testing of antimicrobial activity.
In the 1,3-dipolar cycloaddition of aliphatic nitrile to selected olefins, a series of 4,5-dihydroisoxazoles substituted with various functional groups, ester, carbonyl and ethereal, was obtained. These compounds were investigated for antimicrobial activity on chosen strains.
Zadrozna
I
I
Warsaw University of Technology, Faculty of Chemistry, Division of Organic Chemistry, Poland. zarodna@ch.pw.edu.pl
Kurkowska
J
J
Kruszewska
H
H
Makuch
I
I
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010080:Oxazoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects; D013237:Stereoisomerism
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D010080:Oxazoles