title: Microcalorimetric study of the toxic effect of sodium selenite on the mitochondria metabolism of Carassius auratus liver.
abstract: The fundamental thermogenesis curves of the metabolic process of liver mitochondria from Carassius auratus and the toxic effect of Na2SeO3 on it were studied by using an LKB-2277 bioactivity monitor, ampoule method, at 28 degrees C. From the thermogenesis curves, the thermokinetic equations were established under different conditions. The kinetics show that a low concentration of Na2SeO3 (1-4 mg/L) had promoting action on the metabolism process of Carassius aurantus liver mitochondria, but that a high concentration of Na2SeO3 (8-16 mg/L) inhibited the mitochondria metabolism.
authors.affiliation: Department of Chemistry, Wuhan University, People's Republic of China.
authors.forename: X
authors.initials: X
authors.lastname: Li
authors.forename: Y
authors.initials: Y
authors.lastname: Liu
authors.forename: F
authors.initials: F
authors.lastname: Deng
authors.forename: C
authors.initials: C
authors.lastname: Wang
authors.forename: S
authors.initials: S
authors.lastname: Qu
mesh_terms: D000818:Animals; D002151:Calorimetry / Q000379:methods*; D006054:Goldfish / Q000378:metabolism*; D006358:Hot Temperature; D007700:Kinetics; D008930:Mitochondria, Liver / Q000187:drug effects*; D018038:Sodium Selenite / Q000737:chemistry / Q000633:toxicity*; D013696:Temperature; D013816:Thermodynamics
chemical_list: D018038:Sodium Selenite