title: Type A Niemann-Pick disease.
abstract: Niemann-Pick disease (NPD) represents a type of lysosomal storage diseases in which sphingomyelin accumulates in the histocytes and reticuloendothelial cells of the spleen, liver, lymph nodes, bone marrow and central nervous system. We report a child with massive hepatosplenomegaly, lymphadenopathy, mental retardation and widespread papulonodular lesions. His clinical features conform to the type A subgroup of NPD.
authors.affiliation: Kingdom of Saudi Arabia National Guard, Health Affairs-Western Region, Jeddah. raddadiaa@ngha.med.edu
authors.forename: A A
authors.initials: AA
authors.lastname: Raddadi
authors.forename: A A
authors.initials: AA
authors.lastname: Al Twaim
mesh_terms: D002675:Child, Preschool; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009542:Niemann-Pick Diseases / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*