[Progression of stage I non-seminomatous germ cell tumors during surveillance. Role of positron emission tomography].
Surveillance is one of the options proposed in the management of stage 1 non-seminomatous germ cell tumours when there is only a low risk of progression. No consensus has yet been reached concerning the modalities of this surveillance and several protocols are available, including the CCAFU protocol. The presence of recurrences in this population at low risk of progression, estimated to be 5%, accounts for the continuing research for more precise predictive factors of occult metastases. Although several studies appear to indicate a useful predictive value for some of these factors, their application in clinical practice still appears to be difficult. PET metabolic imaging (positron emission tomography) could constitute a new approach to staging of these tumours, allowing the detection of tumour sites by an increase of carbohydrate metabolism of malignant cells. However, no study is yet available to define the real place of this technique.
Thuret
R
R
Service d'Urologie, Hôpital d'Instruction des Armées du Val-de-Grâce, 74, boulevard de Port-Royal, 75230 Paris.
Houlgatte
A
A
Fournier
R
R
Desgrandchamps
F
F
Maszelin
P
P
Gaillard
J F
JF
D000328:Adult; D018450:Disease Progression; D018237:Germinoma / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging*; D014055:Tomography, Emission-Computed
Progression des tumeurs germinales non séminomateuses de stade I sous surveillance. Place de la tomographie à émission de positons.