title: Double-blind pilot-study on the efficacy of enzyme therapy in advanced colorectal cancer.
abstract: All tested variables showed a tendency in favor for Wobe-Mugos E therapy as addition to standard therapy. Enzymes improve the quality of life by reducing cancer disease typical symptoms, they reduce side effects of chemo-/radiotherapy and they have a potential of prolonging life (preliminary data only).
authors.affiliation: 1st Department of General and Gastrointestinal Surgery, Jagiellonian University, Kraków, Poland.
authors.forename: T
authors.initials: T
authors.lastname: Popiela
authors.forename: J
authors.initials: J
authors.lastname: Kulig
authors.forename: S
authors.initials: S
authors.lastname: Kłek
authors.forename: D
authors.initials: D
authors.lastname: Wachol
authors.forename: P R
authors.initials: PR
authors.lastname: Bock
authors.forename: J
authors.initials: J
authors.lastname: Hanisch
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D002918:Chymotrypsin; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery; D018572:Disease-Free Survival; D004311:Double-Blind Method; D004338:Drug Combinations; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007978:Levamisole / Q000008:administration & dosage; D009362:Neoplasm Metastasis; D010184:Pancreatic Extracts / Q000627:therapeutic use*; D010206:Papain / Q000627:therapeutic use*; D010865:Pilot Projects; D011788:Quality of Life; D015996:Survival Rate; D013949:Thymus Extracts / Q000627:therapeutic use*; D014357:Trypsin
chemical_list: D004338:Drug Combinations; D010184:Pancreatic Extracts; D013949:Thymus Extracts; D007978:Levamisole; C009685:chymotrypsin, papain, trypsin drug combination; D002918:Chymotrypsin; D014357:Trypsin; D010206:Papain; D005472:Fluorouracil