title: AgNORs in hyperplasia, papilloma and oral squamous cell carcinoma.
abstract: Ten inflammatory fibrous hyperplasias, ten papillomas, and nineteen oral squamous cell carcinomas were analyzed by the AgNOR technique to determine if different disturbances of oral epithelia presented different AgNOR counts. The papilloma group showed higher mean AgNOR counts (3.15 +/- 0.58) than the hyperplasia group (1.98 +/- 0.24) and smaller than the well-differentiated oral squamous cell carcinoma group (6.56 +/- 1.25) and poorly differentiated oral squamous cell carcinoma group (7.07 +/- 1.60). The differences among the groups of lesions were statistically significant (P < 0.05) except between the well differentiated oral squamous cell carcinoma group and the poorly differentiated oral squamous cell carcinoma group. Our findings suggest that the cellular proliferation ratio in papillomas is greater than hyperplasias and smaller than carcinomas.
authors.affiliation: Departamento de Clínica, Cirurgia e Patologia Odontológicas, Faculdade de Odontologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.
authors.forename: L M
authors.initials: LM
authors.lastname: Fonseca
authors.forename: M A
authors.initials: MA
authors.lastname: do Carmo
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000648:ultrastructure*; D002455:Cell Division; D004396:Coloring Agents; D004848:Epithelium / Q000648:ultrastructure; D006801:Humans; D006965:Hyperplasia; D009061:Mouth Mucosa / Q000473:pathology* / Q000648:ultrastructure; D009062:Mouth Neoplasms / Q000648:ultrastructure*; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D015588:Observer Variation; D010212:Papilloma / Q000648:ultrastructure*; D012835:Silver Nitrate; D013223:Statistics as Topic
chemical_list: D004396:Coloring Agents; D012835:Silver Nitrate