[Diagnostic and prognostic significance of the antibodies to the myelin basic protein in acute neuroinfections in children].
The development of severe CNS damages including encephalitis is highly probable in some respiratory and exanthemata viral infections (measles, rubella, parotitis). A high level of IgG antibodies to the myelin basic protein was found in patients with parotitis meningitis and rubella encephalitis but it was not high in 80% of patients with encephalitis of the unclear etiology and in 25% of cases with rubella encephalitis. More accurate analysis of clinical, neurovisual and immunologic data revealed a link of appearance of such complications with both the presence of more pronounced demyelinization and prolongation of the disease.
Petrukhin
A S
AS
Idrisova
Zh R
ZhR
Vorov'eva
N L
NL
Gervazieva
V B
VB
Dekonenko
E P
EP
D000208:Acute Disease; D000293:Adolescent; D000907:Antibodies, Bacterial / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D018792:Encephalitis, Viral / Q000175:diagnosis* / Q000276:immunology*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007074:Immunoglobulin G / Q000276:immunology; D008297:Male; D016920:Meningitis, Bacterial / Q000175:diagnosis* / Q000276:immunology*; D004676:Myelin Basic Protein / Q000276:immunology*; D011379:Prognosis
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D004676:Myelin Basic Protein; D007073:Immunoglobulin E
Diagnosticheskoe i prognosticheskoe znachenie antitel k osnovnomu belku mielina pri ostrykh neĭroinfektsiiakh u deteĭ.