title: [Markers of hepatitis C and its various genotypes in patients from Novosibirsk].
abstract: Study of the prevalence of hepatitis C virus (HCV) markers in 153 patients of Municipal Infectious Diseases Clinical Hospital No. 1 in Novosibirsk revealed anti-HCV in 88.2% patients and viral RNA in 69.3% samples. For 93 Siberian HCV isolates 5'-UTR regions were amplified and sequenced. Comparison of these nucleotide sequences with databank showed that 63.4% HCV isolates belonged to subtype 1b, 7.5% to genotype 2, and 18.3% to genotype 3. In the rest HCV isolates the 5'-UTR sequences contained heretofore undescribed nucleotide substitutions, insertions, or deletions.
authors.forename: A V
authors.initials: AV
authors.lastname: Shustov
authors.forename: V P
authors.initials: VP
authors.lastname: Mishin
authors.forename: A Z
authors.initials: AZ
authors.lastname: Maksiutov
authors.forename: N N
authors.initials: NN
authors.lastname: Kiseleva
authors.forename: E G
authors.initials: EG
authors.lastname: Sakharova
authors.forename: N P
authors.initials: NP
authors.lastname: Tolokonskaia
authors.forename: B J
authors.initials: BJ
authors.lastname: Robertson
authors.forename: S V
authors.initials: SV
authors.lastname: Netesov
mesh_terms: D020121:5' Untranslated Regions; D000595:Amino Acid Sequence; D001483:Base Sequence; D015415:Biomarkers; D017931:DNA Primers; D005838:Genotype; D016174:Hepacivirus / Q000145:classification / Q000235:genetics* / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000821:virology*; D006801:Humans; D008969:Molecular Sequence Data; D012367:RNA, Viral / Q000097:blood*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid
chemical_list: D020121:5' Untranslated Regions; D015415:Biomarkers; D017931:DNA Primers; D006508:Hepatitis Antibodies; D012367:RNA, Viral
vernacular_title: Markery virusa gepatita C i razlichnky ego genotipov u patsientov Novosibirska.