title: Epidemiology of pneumococcal disease in children in Germany.
abstract: Recently published and as yet unpublished data allow a reasonable estimate of the annual burden of pneumococcal disease in Germany. At least 277,000 episodes of otitis media and at least 2,000 episodes of sinusitis occur in children under the age of 5 y. Pneumococcal meningitis was found in 200 children under the age of 16 y; the estimate for all age groups ranges from 450 to 1100 cases. Of approximately 150,000 cases of ambulatory pneumococcal pneumonia, at least 63,000-105,000 patients are hospitalized each year.
  
  
  CONCLUSIONS
  Further studies of pneumococcal epidemiology in Germany are needed, and continued surveillance will be necessary for a better understanding of the overall burden of pneumococcal disease in children as well as adults.
authors.affiliation: Department of Pediatrics, Johannes-Gutenberg University, Mainz, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Ziebold
authors.forename: R
authors.initials: R
authors.lastname: von Kries
authors.forename: A
authors.initials: A
authors.lastname: Siedler
authors.forename: H J
authors.initials: HJ
authors.lastname: Schmitt
mesh_terms: D000293:Adolescent; D002648:Child; D003625:Data Collection; D005858:Germany / Q000453:epidemiology; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D008586:Meningitis, Pneumococcal / Q000453:epidemiology; D010033:Otitis Media / Q000453:epidemiology; D011008:Pneumococcal Infections / Q000453:epidemiology*; D011159:Population Surveillance; D012703:Serotyping; D012852:Sinusitis / Q000453:epidemiology; D013296:Streptococcus pneumoniae / Q000145:classification