title: Antibacterial activity of Citrus reticulata peel extracts.
abstract: Citrus peels were successively extracted with hexane, chloroform and acetone using a soxhlet extractor. The hexane and chloroform extracts were fractionated into alcohol-soluble and alcohol-insoluble fractions. These fractions were tested against different gram positive and gram negative bacteria. The EtOH-soluble fraction was found to be most effective. Fractionation of EtOH-soluble fraction on silica gel column yielded three polymethoxylated flavones, namely desmethylnobiletin, nobiletin and tangeretin. Their structures were confirmed by UV, 1H, 13C NMR and mass spectral studies. The findings indicated a potential of these natural compounds as biopreservatives in food applications.
authors.affiliation: Central Food Technological Research Institute, Mysore, India. gkjp@yahoo.com
authors.forename: G K
authors.initials: GK
authors.lastname: Jayaprakasha
authors.forename: P S
authors.initials: PS
authors.lastname: Negi
authors.forename: S
authors.initials: S
authors.lastname: Sikder
authors.forename: L J
authors.initials: LJ
authors.lastname: Rao
authors.forename: K K
authors.initials: KK
authors.lastname: Sakariah
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001407:Bacillus / Q000187:drug effects; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D002957:Citrus; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012639:Seeds; D012997:Solvents; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D012997:Solvents