title: Synthesis and biological activity of 6-substituted-3-[2-(5-substituted-2-furfurylidenehydrazino)-4-thiazolyl] coumarins.
abstract: A series of coumarin-derivatives (5) were synthesized by the reaction of 5-substituted-2-furfuraldehyde thiosemicarbazones with 3-bromoacetyl-6-substituted coumarins. The structures of newly synthesized compounds were confirmed on the basis of their elemental analysis, NMR and mass spectral data. Some selected compounds were screened for their antibacterial activity employing disc diffusion technique.
authors.affiliation: Department of Studies in Chemistry, Mangalore University, Mangalagangothri-574 199, India.
authors.forename: B
authors.initials: B
authors.lastname: Kalluraya
authors.forename: P
authors.initials: P
authors.lastname: Vishwanatha
authors.forename: A M
authors.initials: AM
authors.lastname: Isloor
authors.forename: G
authors.initials: G
authors.lastname: Rai
authors.forename: M
authors.initials: M
authors.lastname: Kotian
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D015169:Colony Count, Microbial; D003374:Coumarins / Q000138:chemical synthesis* / Q000494:pharmacology; D006834:Hydrazines / Q000138:chemical synthesis* / Q000494:pharmacology; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D003374:Coumarins; D006834:Hydrazines; D013844:Thiazoles