title: Bladder cancer--genetic overview.
abstract: BACKGROUND
  This article review the serial genetic changes which are responsible to the initiation and progression of bladder cancer. Knowledge of the exact genetic alteration has a direct implication on the development of knew more sensitive and specific tool for an early diagnosis and better prognosis calculations.
  
  
  CONCLUSIONS
  Bladder cancer develop and progress through a series of genetic alterations. Understanding of the genetic mechanisms which lead to malignant transformation gave rise to the development of various genetic mechanisms which lead to malignant transformation gave rise to the development of various genetic tools providing better ability of early detection and more accurate prognosis prediction.
authors.affiliation: Department of Urology, Bnai Zion Medical Center, 47 Golomb St., Haifa, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Halachmi
authors.forename: R
authors.initials: R
authors.lastname: Madeb
authors.forename: A
authors.initials: A
authors.lastname: Kravtsov
authors.forename: B
authors.initials: B
authors.lastname: Moskovitz
authors.forename: N
authors.initials: N
authors.lastname: Halachmi
authors.forename: O
authors.initials: O
authors.lastname: Nativ
mesh_terms: D002869:Chromosome Aberrations; D016147:Genes, Tumor Suppressor; D006801:Humans; D011379:Prognosis; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology