Clostridium difficile colitis following antibiotic prophylaxis for dental procedures.
Clostridium difficile-induced diarrhea and colitis are common complications of therapeutic courses of antibiotics in the hospital setting. We report a case of Clostridium difficile colitis following antibiotic prophylaxis for endocarditis prior to dental procedures in the community setting. The infection necessitated hospital admission and a prolonged hospital stay. Dental practitioners must be aware of the significance of the disease and the risk associated with antibiotics, whether they are used for prophylaxis or treatment.
Bombassaro
A M
AM
Department of Pharmacy, London Health Sciences Centre, London, Ont. Annemarie.Bombassaro@lhsc.on.ca
Wetmore
S J
SJ
John
M A
MA
D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis / Q000009:adverse effects*; D001427:Bacterial Toxins / Q000032:analysis; D002981:Clindamycin / Q000009:adverse effects*; D016360:Clostridioides difficile; D017742:Dental Care for Chronically Ill; D003967:Diarrhea / Q000188:drug therapy / Q000209:etiology; D004761:Enterocolitis, Pseudomembranous / Q000188:drug therapy / Q000209:etiology*; D004768:Enterotoxins / Q000032:analysis; D004917:Erythromycin / Q000009:adverse effects; D005260:Female; D006331:Heart Diseases; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D004768:Enterotoxins; D008795:Metronidazole; D002981:Clindamycin; D004917:Erythromycin