title: [The quality of sleep associated with polypharmacy].
abstract: OBJECTIVE
  Study of the association between multiple medication and the quality of sleep.
  
  
  METHODS
  Observational, cross-sectional study through two-stage sampling of 1053 people with a questionnaire and application of the Pittsburgh Sleep Quality Interview (PSQI).
  
  
  METHODS
  Primary care. Population covered by health centres in the province of Valladolid.
  
  
  METHODS
  Adults over 18 who attended health centres in Valladolid province.
  
  
  RESULTS
  As consumption of multiple drugs rose, there was significant deterioration in the overall quality of sleep and each of the following components: subjective quality, latency of sleep, duration of sleep, extrinsic disturbances and consumption of sleeping draughts. No differences were found for day-time repercussions. When psychiatric drug consumption was excluded from the study (to avoid the risk of bias in psychiatric illnesses), deterioration in the quality of sleep, on adding up the remaining therapeutic groups of drugs, was still found.
  
  
  CONCLUSIONS
  The fact of consuming multiple drugs chronically may condition a deterioration in sleep quality, which will stimulate us to combat this symptom with more drugs and so further aggravate the problem. New prospective studies need to be undertaken to find out the reasons.
authors.affiliation: Centro de Salud Tórtola, Facultad de Medicina, Valladolid.
authors.forename: V M
authors.initials: VM
authors.lastname: Vázquez García
authors.forename: J A
authors.initials: JA
authors.lastname: Macías Fernández
authors.forename: F
authors.initials: F
authors.lastname: Alonso del Teso
authors.forename: R M
authors.initials: RM
authors.lastname: González las Heras
authors.forename: G
authors.initials: G
authors.lastname: de Teresa Romero
authors.forename: A A
authors.initials: AA
authors.lastname: Alvarez Hurtado
authors.forename: J I
authors.initials: JI
authors.lastname: Carretero Ares
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D003430:Cross-Sectional Studies; D006801:Humans; D019338:Polypharmacy; D011619:Psychotropic Drugs / Q000008:administration & dosage; D012890:Sleep / Q000187:drug effects* / Q000502:physiology; D012893:Sleep Wake Disorders / Q000139:chemically induced
chemical_list: D011619:Psychotropic Drugs
vernacular_title: La calidad del sueño asociada a la polimedicación.