[Study on the biocompatibility and toxicology of biomaterials--poly(epsilon-caprolactone)].
Four observation indexes were selected to evaluate the biocompatibility and toxicology of biodegradable materials poly(epsilon-caprolactone)(PCL), which is synthesized in our laboratory using Ti(OBu)4 as an initiator. The results showed that PCL films had a mild inflammatory reaction in the early days of planting and after 3 months the inflammation basically disappeared. We conclude that PCL material possesses good biocompatibility and has a good developmental prospect.
Chen
J
J
Department of Pharmaceutical Science, Nanfang Hospital, First Medical University of PLA, Guangzhou 510515.
Huang
C
C
Chen
Z
Z
D000818:Animals; D001672:Biocompatible Materials / Q000633:toxicity*; D005260:Female; D008297:Male; D008422:Materials Testing; D051379:Mice; D011091:Polyesters / Q000633:toxicity*; D011817:Rabbits; D018675:Toxicity Tests
D001672:Biocompatible Materials; D011091:Polyesters; C016240:polycaprolactone