title: [Nervous system changes in adrenal failure].
abstract: OBJECTIVE
  To study nervous systems in chronic adrenal failure (CAF).
  
  
  METHODS
  262 patients with CAF were studied clinically, biochemically and electrophysiologically before and after treatment.
  
  
  RESULTS
  The patients were found to have syndromes of vegetovascular dystonia by hypotonic type, syncopal paroxysms, myastenic, minor strokes, dyscirculatory-dysmetabolic encephalopathy, polyneuropathy. A direct correlation was established between the severity and duration of adrenal failure (AF), lowering of adrenal cortex hormones, coefficient Na/K and clinical manifestations of the neurological syndromes. Adequate hormone replacing and symptomatic therapy promoted a regress of neurological disorders in most of the patients especially in mild and moderate AF.
  
  
  CONCLUSIONS
  Adequate therapy corrects neurological disturbances in patients with chronic NN.
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Martynov
authors.forename: V N
authors.initials: VN
authors.lastname: Demianiuk
authors.forename: N T
authors.initials: NT
authors.lastname: Starkova
authors.forename: N A
authors.initials: NA
authors.lastname: Shuvakhina
authors.forename: E L
authors.initials: EL
authors.lastname: Sokov
authors.forename: E V
authors.initials: EV
authors.lastname: Malkova
authors.forename: N V
authors.initials: NV
authors.lastname: Nozdriukhina
authors.forename: N F
authors.initials: NF
authors.lastname: Borisova
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000097:blood; D000309:Adrenal Insufficiency / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D000328:Adult; D000368:Aged; D002490:Central Nervous System / Q000503:physiopathology*; D002648:Child; D002908:Chronic Disease; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology / Q000503:physiopathology*; D011379:Prognosis
chemical_list: D000305:Adrenal Cortex Hormones
vernacular_title: Izmenenie nervnoĭ sistemy pri nadpochechnikovoĭ nedostatochnosti.