title: [A century of progress in the knowledge and treatment of nephroblastoma].
abstract: Since its initial description by Max Wilms over a century ago, nephroblastoma has benefited from considerable improvements both in terms of basic knowledge about it and management of it. Today, the majority of these very young patients can expect a long-term survival in excess of 90% at the price of a light therapy that combines surgical resection, chemotherapy based on ill-toxic agents, and in selected cases, radiotherapy of remarkably low toxicity. The contribution of large international studies will be emphasized here.
authors.affiliation: Département de radiothérapie, institut Gustave-Roussy, 39, rue Camille-Desmoulins, 94805 Villejuif, France.
authors.forename: J L
authors.initials: JL
authors.lastname: Habrand
authors.forename: F
authors.initials: F
authors.lastname: Pein
authors.forename: V
authors.initials: V
authors.lastname: Moncho
mesh_terms: D002648:Child; D005260:Female; D049673:History, 20th Century; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000266:history* / Q000628:therapy; D009141:Musculoskeletal System / Q000187:drug effects / Q000528:radiation effects; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000266:history / Q000628:therapy; D010053:Ovary / Q000528:radiation effects; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic / Q000266:history; D012120:Respiration Disorders / Q000209:etiology / Q000266:history; D009396:Wilms Tumor / Q000175:diagnosis / Q000266:history* / Q000628:therapy
vernacular_title: Un siècle de progrès dans la connaissance et le traitement du néphroblastome.