Base-catalyzed amination of olefins: an example of an environmentally friendly synthesis of amines.
The base-catalyzed amination of aromatic olefins is described as an environmentally friendly synthesis of various beta-arylethylamines. Primary and secondary aliphatic amines as well as aromatic amines react with styrene derivatives to give the corresponding beta-arylethylamines in high yield up to 99%. While aliphatic amines react with styrenes in the presence of n-BuLi as the pre-catalyst, anilines can be olefinated using KOtBu as the catalyst.
Beller
M
M
Institut für Organische Katalyseforschung an der Universität Rostock e. V., Germany.
Breindl
C
C
D000475:Alkenes / Q000138:chemical synthesis*; D002384:Catalysis; D002617:Chemical Industry; D004787:Environmental Pollution / Q000517:prevention & control; D005021:Ethylamines / Q000737:chemistry*; D013343:Styrenes / Q000737:chemistry
D000475:Alkenes; D005021:Ethylamines; D013343:Styrenes