[Use of the novel taurine derivative for prevention of changes in the systemic hemodynamics induced by electric stimulation of the rabbit aorta].
The influence of a new taurine derivative on hemodynamic changes induced by electrostimulation of an aortic reflexogenic zone was studied. It is shown that 3-hour electrostimulation increased total peripheral resistance and decreased cardiac output and aortic pressure. Intravenous infusion of the taurine derivative during electrostimulation normalized abnormal hemodynamic characteristics.
Sapronov
N S
NS
Novikov
V P
VP
Torkunov
P A
PA
Siniukhin
A B
AB
D000818:Animals; D001011:Aorta / Q000502:physiology; D001794:Blood Pressure / Q000187:drug effects; D002302:Cardiac Output / Q000187:drug effects; D002317:Cardiovascular Agents / Q000494:pharmacology*; D004558:Electric Stimulation; D004569:Electroencephalography; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D011817:Rabbits; D013318:Stroke Volume / Q000187:drug effects; D013654:Taurine / Q000031:analogs & derivatives / Q000494:pharmacology*; D014655:Vascular Resistance / Q000187:drug effects
C423302:2-phenylisopropyl-2-aminosulfoisopropylamide; D002317:Cardiovascular Agents; D013654:Taurine