Eyelash hypertrichosis in a patient treated with topical latanoprost.
We describe a female patient with a history of primary open-angle glaucoma who, following treatment with topical latanoprost, a synthetic prostaglandin F2 alpha analog, developed hypertrichosis of the eyelashes. Hypertrichosis, a recently described side effect of latanoprost--together with iridal pigmentation--represents a potentially permanent cosmetic side effect associated with the use of this highly effective intraocular pressure-lowering agent. The molecular mechanism underlying latanoprost-induced hypertrichosis is unknown.
Department of Medicine, New York University School of Medicine, New York, USA.
B E
BE
Strober
S
S
Potash
M E
ME
Grossman
D000368:Aged; D000959:Antihypertensive Agents / Q000009:adverse effects*; D005140:Eyelashes; D005260:Female; D006801:Humans; D006983:Hypertrichosis / Q000139:chemically induced*; D000077338:Latanoprost; D011461:Prostaglandins F, Synthetic / Q000009:adverse effects*
D000959:Antihypertensive Agents; D011461:Prostaglandins F, Synthetic; D000077338:Latanoprost