[The role of PKC isoforms in tumorigenicity and apoptotic cell death].
Protein kinase C comprises a family of at least 13 distinct serine/threonine kinase isoenzymes that have important actions in transmembrane signal transduction pathways and have been reported to regulate cell proliferation, differentiation, cell-to-cell interaction, cytoskeletal functions, gene transcription, apoptosis and drug resistance. The results of investigations show differential redistribution isoenzymes in each organ and their specific activity in determined diseases.
Rybczyńska
M
M
Zakład Chemii Klinicznej, Katedra Biochemii Farmaceutycznej, Akademia Medyczna im. K. Marcinkowskiego w Poznaniu.
Ksiazek
K
K
Kaczmarek
J
J
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism; D009369:Neoplasms / Q000503:physiopathology*; D011493:Protein Kinase C / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology
D007527:Isoenzymes; D011493:Protein Kinase C