Development of spectral colour banding in cytogenetic analysis.
We developed a novel chromosome banding technique-spectral colour banding (SCAN). With this technique we displayed a multicolour banding pattern that almost entirely correlated with the corresponding G-banding pattern. With SCAN analysis we could identify the chromosome-band origin of double minute chromosomes in gastric cancer. Our preliminary use of this technique suggests that it has significant clinical applications for cytogenetic analysis.
N
N
Kakazu
E
E
Ashihara
S
S
Hada
T
T
Ueda
H
H
Sasaki
M
M
Terada
T A
TA
See
D018279:Carcinoma, Signet Ring Cell / Q000235:genetics; D002871:Chromosome Banding / Q000379:methods*; D002879:Chromosomes, Human, Pair 10; D003116:Color; D005453:Fluorescence; D006801:Humans; D008297:Male; D008875:Middle Aged; D009693:Nucleic Acid Hybridization; D013274:Stomach Neoplasms / Q000235:genetics