Miniaturized total analysis systems for biological analysis.
This review article discusses and documents the basic philosophies, concepts and current advances in the field of micro-TAS development, with special emphasis on applications in the arena of biosciences. After a brief overview of miniaturization theory and fabrication techniques, areas of microfluidic component development, detection protocols, biochemical assays, and integrated biological analyses are addressed.
Jakeway
S C
SC
Zeneca SmithKline Beecham Centre for Analytical Sciences, Imperial College, London, UK.
de Mello
A J
AJ
Russell
E L
EL
D001669:Biochemical Phenomena; D002845:Chromatography / Q000379:methods; D019075:Electrophoresis, Capillary / Q000379:methods; D006801:Humans; D008832:Microchemistry / Q000295:instrumentation* / Q000379:methods*; D008904:Miniaturization; D016133:Polymerase Chain Reaction / Q000379:methods