Impact of hysteroscopy on disease-free survival in clinically stage I endometrial cancer patients.
Recent data strongly suggest tumor cell dissemination of endometrial carcinoma cells in the course of fluid hysteroscopy. In patients who had endometrial cancer which was (except for peritoneal cytology) confined to the uterus, the disease-free survival (DFS) of 135 patients who underwent hysteroscopy prior to staging laparotomy was compared with the DFS of 127 patients without hysteroscopy. After a median follow-up of 23 months, 10 patients experienced tumor recurrence. Although there was a trend towards a higher incidence of positive peritoneal cytology at laparotomy in patients who underwent hysteroscopy, this difference did not achieve statistical significance (P = 0.47). For 5 years, the DFS was 92.4% in patients with hysteroscopy and 84.7% in patients without hysteroscopy before laparotomy (log-rank, P = 0.782). Our data therefore suggest a similar short-term DFS in endometrial cancer patients with and without hysteroscopy prior to laparotomy.
Division of Gynecology, Department of Gynecology and Obstetrics, University Hospital of Vienna, Vienna, Austria;Department of Gynecology and Obstetrics, Iniversity Hospital of Graz, Graz, Austria;Department of Gynecology and Obstetrics, General Hospital Wilhelminenspital, Vienna, Austria;Department of Gynecology and Obstetrics, General Hospital Salzburg, Salzburg, Austria;Department of Gynecology, Hospital Barmherzige Schwestern, Linz, Austria;Department of Gynecology and Obstetrics, General Hospital Lainz, Vienna, Austria;Department of Gynecology and Obstetrics, General Hospital Sozialmedizinisches Zentrum Ost/Donauspital, Vienna, Austria;Department of Gynecology and Obstetrics, General Hospital Rudolfstiftung, Vienna, Austria;Department of Gynecology and Obstetrics, General Hospital Dornbirn, Dornbirn, Austria; and Department of Gynecology and Obstetrics, Kaiser Franz Josef Hospital, Vienna, Austria.
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Kapshammer
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