[Effective treatment of cardiac failure with caposide at an outpatient clinic].
OBJECTIVE
To evaluate results of long-term outpatient use of caposide in patients with cardiac failure.


METHODS
74 patients (59 males and 15 females aged 40-76 years) with chronic cardiac failure (CCF) received caposide in individual doses. CCF was caused by ischemic heart disease (IHD) and dilated cardiomyopathy in 65 and 9 patients, respectively. The treatment effect was assessed by changes in clinical symptoms, quality of life and physical activity.


RESULTS
Clinical symptoms, functional class of IHD, exercise tolerance and quality of life improved. Serious side effects were absent.


CONCLUSIONS
Caposide can be considered as first-line therapy in outpatient treatment of patients with CCF of different severity as monotherapy and adjuvant in combined treatment.
Bart
B Ia
BIa
Larina
V N
VN
Dergunova
E N
EN
D000368:Aged; D000553:Ambulatory Care; D002216:Captopril / Q000009:adverse effects / Q000627:therapeutic use*; D002303:Cardiac Output, Low / Q000188:drug therapy*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
D004338:Drug Combinations; C044959:captopril, hydrochlorothiazide drug combination; D006852:Hydrochlorothiazide; D002216:Captopril