GeneSplicer: a new computational method for splice site prediction.
GeneSplicer is a new, flexible system for detecting splice sites in the genomic DNA of various eukaryotes. The system has been tested successfully using DNA from two reference organisms: the model plant Arabidopsis thaliana and human. It was compared to six programs representing the leading splice site detectors for each of these species: NetPlantGene, NetGene2, HSPL, NNSplice, GENIO and SpliceView. In each case GeneSplicer performed comparably to the best alternative, in terms of both accuracy and computational efficiency.
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.
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D000465:Algorithms; D017398:Alternative Splicing / Q000235:genetics*; D017360:Arabidopsis / Q000235:genetics; D019295:Computational Biology / Q000379:methods*; D004247:DNA / Q000235:genetics; D016208:Databases, Factual; D005796:Genes / Q000235:genetics; D015894:Genome, Human; D018745:Genome, Plant; D006801:Humans
D004247:DNA