The surgical aspects of the totally implantable hepatic artery infusion pump.
The design of a totally implantable hepatic artery infusion pump in 1969 made the use of hepatic artery infusion feasible and practical as a treatment for patients with hepatic neoplasms. The implantable pumps could function for long periods and reliably infuse a measured quantity of drug into the hepatic artery in a continuous fashion. This enabled oncologists to give much higher doses of chemotherapy directly into the blood supply of the tumors as well as to use a continuous infusion schedule.
Kemeny
M M
MM
Division of Surgical Oncology, State University of New York, Stony Brook 11794-8191, USA. kemeny@surg.som.sunysb.edu
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004867:Equipment Design; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial / Q000295:instrumentation; D008113:Liver Neoplasms / Q000188:drug therapy*; D011182:Postoperative Care
D000970:Antineoplastic Agents