Resolving the Heuser-Ceccarelli debate.
Nearly 30 years ago, a debate over two disparate models of synaptic vesicle retrieval arose. Subsequent investigations to determine which model was correct proved inconclusive and served only to further the debate. However, recent evidence has begun to suggest that both models are valid and relevant in understanding the complex nature of vesicle recycling.
Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA. wilk@cellbio.wustl.edu
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D000818:Animals; D001665:Binding Sites / Q000502:physiology; D004705:Endocytosis / Q000502:physiology*; D005089:Exocytosis / Q000502:physiology*; D008954:Models, Biological; D009469:Neuromuscular Junction / Q000378:metabolism*; D013572:Synaptic Vesicles / Q000378:metabolism*