The significance of accurate dielectric tissue data for hyperthermia treatment planning.
For hyperthermia treatment planning, dielectric properties of several tissue types are required. Since it is difficult to perform patient specific dielectric imaging, default values based on literature data are used. However, these show a large spread (approximately 50%). Consequently, it is important to know what limit this spread imposes on the accuracy of the SAR and subsequently on the temperature distributions. Hyperthermia treatment plans performed with different values for the dielectric properties were compared. This showed that a spread of 50% resulted in the average absolute difference of approximately 20% in both SAR and temperature distributions (heat sink approach) for regional hyperthermia. For interstitial hyperthermia, a spread of 25% resulted in the averaged absolute difference of approximately 10% in the SAR distributions and 5% in the temperature distributions (heat sink approach). Considering other problems that hamper hyperthermia treatment planning, it can be concluded that default values for the dielectric properties suffice.
Department of Radiotherapy, University Medical Center Utrecht, The Netherlands. j.vandekamer@radth.ruu.nl
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Van de Kamer
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Van Wieringen
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De Leeuw
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Lagendijk
D001932:Brain Neoplasms / Q000628:therapy; D004553:Electric Conductivity; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D008954:Models, Biological; D008962:Models, Theoretical; D010386:Pelvic Neoplasms / Q000628:therapy; D019047:Phantoms, Imaging; D014054:Tomography / Q000379:methods