Evaluation of Binax NOW, an assay for the detection of pneumococcal antigen in urine samples, performed among pediatric patients.
In our evaluation of a new assay for the detection of pneumococcal antigen in urine (Binax NOW; Binax), the test result was no more likely to be positive among 88 children with radiographically confirmed pneumonia than among 198 control subjects; however, it was significantly more likely to be positive among children who were nasopharyngeal carriers of pneumococci. This test is not likely to be useful for distinguishing children with pneumococcal pneumonia from those who are merely colonized.
Respiratory Disease Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. sfd2@cdc.gov
S F
SF
Dowell
R L
RL
Garman
G
G
Liu
O S
OS
Levine
Y H
YH
Yang
D000942:Antigens, Bacterial / Q000652:urine*; D002353:Carrier State / Q000175:diagnosis* / Q000382:microbiology; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009305:Nasopharynx / Q000382:microbiology*; D011018:Pneumonia, Pneumococcal / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000382:microbiology; D011859:Radiography; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D013296:Streptococcus pneumoniae / Q000276:immunology / Q000302:isolation & purification*; D014556:Urine / Q000382:microbiology*
D000942:Antigens, Bacterial; D011933:Reagent Kits, Diagnostic