Thalamic hand dystonia: an MRI anatomoclinical study.
Focal dystonia has been attributed to lesions involving the basal ganglia and/or thalamus. Hand dystonia was studied in a patient with a unilateral thalamic infarction documented by MRI. A 18-year-old girl presented with severe isolated dystonia of the right hand as a sequel of perinatal infarction. MRI scan revealed infarction affecting part of the dorsomedian, lateral posterior, ventral lateral, ventral posterior lateral nuclei, and centromedian-parafascicular nucleus of the contralateral thalamus. The unique MRI anatomoclinical presentation of this case, taken together with the literature data, could provide evidence that a lesion affecting one or several thalamic nuclei, including the centromedian nucleus, can induce hand dystonia.
Deleu
D
D
Department of Clinical Pharmacology Medecine (Neurology), College of Medicine, P.O. Box 35, Sultan Qaboos University, Al-Khod, Muscat-123, Sultanate of Oman.
Lagopoulos
M
M
Louon
A
A
D000293:Adolescent; D002544:Cerebral Infarction / Q000150:complications* / Q000175:diagnosis; D003131:Combined Modality Therapy; D004292:Dominance, Cerebral; D020821:Dystonic Disorders / Q000188:drug therapy / Q000209:etiology* / Q000628:therapy; D005260:Female; D006227:Hand Deformities, Acquired / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D013788:Thalamus / Q000098:blood supply* / Q000503:physiopathology; D004561:Transcutaneous Electric Nerve Stimulation