Plasma erythropoietin in newborn lambs.
In the present study early postnatal changes in erythropoietin (Epo) level and hemoglobin concentration in 8 lambs were examined. Plasma Epo was estimated by a monoclonal enzyme-immunoassay (ELISA), developed for human Epo. In all the lambs, except one, Epo was low, or undetectable, immediately after birth. Within 6-12 h after birth, a marked increase in plasma Epo was found in 4 of the lambs. Within 3-7 days after birth, Epo was back to low levels. In the lamb with high Epo levels at birth, drastic decreases were observed during the next 6 h. There was no obvious correlation between the hemoglobin concentrations and the changes in plasma Epo.
Department of Biochemistry, Physiology and Nutrition, The Norwegian School of Veterinary Science, Oslo.
O V
OV
Sjaastad
A K
AK
Egeli
A K
AK
Blom
T
T
Framstad
D000818:Animals; D000831:Animals, Newborn / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D004921:Erythropoietin / Q000097:blood*; D006454:Hemoglobins / Q000032:analysis; D012756:Sheep / Q000097:blood*
D006454:Hemoglobins; D004921:Erythropoietin