Frequency of chlamydial antibodies in patients with internal derangement of the temporomandibular joint.
OBJECTIVE
This study investigates whether an increased frequency of serum antibodies to Chlamydia trachomatis is found in patients with internal derangement of the temporomandibular joint (TMJ).


METHODS
An indirect immunofluorescence antibody assay for the detection of serum immunoglobulin G antibodies for C trachomatis was used for most patients. Forty-one female patients were evaluated.


RESULTS
Three of 41 patients (7%) had serum antibody titers that were considered positive for active C trachomatis infection. Eleven patients (27%) were considered to have had a past infection based on the immunoglobulin G or immunoglobulin A titer results. Using the binomial test, we found that the probability of observing 14 positive results (34%) was significant (P < .0001).


CONCLUSIONS
An increase in the frequency of serum antibodies to C trachomatis was found in patients with internal derangement of the TMJ. Serologic testing for antibodies to bacteria associated with reactive arthritis might be useful in the evaluation of patients with internal derangement of the TMJ.
Baylor University Medical Center, Dallas, TX, USA. chenry@pol.net
C H
CH
Henry
M C
MC
Pitta
L M
LM
Wolford
D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D016918:Arthritis, Reactive / Q000382:microbiology*; D002690:Chlamydia Infections / Q000097:blood*; D002692:Chlamydia trachomatis / Q000276:immunology / Q000472:pathogenicity*; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008875:Middle Aged; D013705:Temporomandibular Joint Disorders / Q000097:blood / Q000382:microbiology*
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G