[Monitoring dopamine release by fast cyclic voltammetry: an in vivo study].
OBJECTIVE
Using fast cyclic voltammetry (FCV) and carbon fibre microelectrode (CFMe), we monitored dopamine (DA) release from caudate putamen(CPu), nucleus accumbens(Acb) and central amygdaloid nucleus(CAN) of normal rats in vivo, in order to find out the suitable parameters to evoke DA release of certain area. DA release was evoked by electrical stimulation of medial forebrain bundle(MFB) or ventral tegmental area(VTA).


RESULTS
DA release from CPu, Acb or CAN were different in contents and the characteristics of dynamics.


CONCLUSIONS
Different parameters should be used according to the different sites of stimulation in order to get the maximal DA release during the experiment.
Department of Physiology, Medical College of Qingdao University, Qingdao 266021.
J X
JX
Xie
Y
Y
Zhou
H
H
Jiang
D000818:Animals; D001921:Brain / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism*; D004558:Electric Stimulation; D004594:Electrophysiology / Q000379:methods; D005260:Female; D066298:In Vitro Techniques; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley
D004298:Dopamine