Relationships between tissue concentrations of polycyclic aromatic hydrocarbons and antioxidative responses of marine mussels, Perna viridis.
Local mussels, Perna viridis, were transplanted from a relatively clean site to various polluted sites in Hong Kong. After a 30-day field exposure, different antioxidant parameters including glutathione S transferase (GST), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), NADPH DT-diaphorase (DT-d), glutathione (GSH) and lipid peroxidation were quantified, and tissue concentrations of benzo[a]pyrene (B[a]P) as well as a total of five polycyclic aromatic hydrocarbons (PAHs) with potential carcinogenicity were determined for individual mussels. Results indicated that: (1) tissue concentrations of B[a]P and total PAHs from the same site were highly variable; (2) gill SOD, DT-d and lipid peroxidation showed no response to tissue pollutants; (3) the majority of the antioxidant parameters were induced by increasing tissue pollutant concentrations; and (4) amongst the various parameters, oxyradical scavenger GSH best correlated with tissue concentrations of pollutants.
Department of Biology and Chemistry, Centre for Coastal Pollution and Conservation, City University of Hong Kong, Tat Chee Avenue, Kowloon, SAR, Hong Kong, Hong Kong.
C C
CC
Cheung
G J
GJ
Zheng
A M
AM
Li
B J
BJ
Richardson
P K
PK
Lam
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D049872:Bivalvia / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D005980:Glutathione Reductase / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D006723:Hong Kong; D015227:Lipid Peroxidation; D009252:NADPH Dehydrogenase / Q000378:metabolism; D011084:Polycyclic Aromatic Hydrocarbons / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism; D014877:Water Pollution, Chemical / Q000009:adverse effects*
D000975:Antioxidants; D011084:Polycyclic Aromatic Hydrocarbons; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D009252:NADPH Dehydrogenase; D005980:Glutathione Reductase; D005982:Glutathione Transferase