[Observation on inhibitory effect of tetrandrine on the growth of human skin fibroblast in vitro].
The effect of tetrandrine on the growth of human skin fibroblasts was observed in vitro culture. The result revealed that tetrandrine significantly inhibited the growth of fibroblast. The higher the concentration of tetrandrine, the higher the inhibition rate, forming a time-dependent relationship. The possible value of tetrandrine in the treatment of hypertrophic scar is discussed.
Burn Institute, The First Affiliated Hospital of Jiangxi Medical College, Nanchang 330006.
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Liu
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Li
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Cao
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Su
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Wang
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Wu
D000470:Alkaloids / Q000008:administration & dosage / Q000494:pharmacology*; D044182:Benzylisoquinolines; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D005347:Fibroblasts / Q000166:cytology*; D006801:Humans; D012867:Skin / Q000166:cytology*; D013997:Time Factors
D000470:Alkaloids; D044182:Benzylisoquinolines; D002121:Calcium Channel Blockers; C009438:tetrandrine