Multiple focal nodular hyperplasia and steatosis: Atypical imaging characteristics.
Focal nodular hyperplasia is a rare, benign condition of the liver. A 28-year-old woman with malignant melanoma, mild liver enzyme abnormalities, steatohepatitis and newly documented hepatic lesions is described. Ultrasound, computed tomography and magnetic resonance imaging suggested only areas of focal fatty sparing but could not eliminate the concern for metastases. A (99m)technetium-labelled sulphur colloid scan, however, revealed areas of increased uptake consistent with multiple focal nodular hyperplasia. This diagnosis was ultimately confirmed with a liver biopsy. The investigation of a patient with a malignancy and expanding hepatic lesions is challenging. This case illustrates the usefulness of the (99m)technetium-labelled sulphur colloid scan in the evaluation of patients with hepatic lesions.
Department of Medicine, Liver Disease Unit, London Health Sciences Centre, University of Western Ontario, London, Ontario N6A 5A5, Canada.
R P
RP
Myers
D
D
Downey
S
S
Chakrabarti
P J
PJ
Marotta
D000273:Adipose Tissue / Q000473:pathology*; D000328:Adult; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005234:Fatty Liver / Q000150:complications / Q000175:diagnosis; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000150:complications / Q000175:diagnosis*; D005682:Gadolinium; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008545:Melanoma / Q000150:complications / Q000601:surgery; D012680:Sensitivity and Specificity; D012878:Skin Neoplasms / Q000150:complications / Q000601:surgery; D014057:Tomography, X-Ray Computed
D005682:Gadolinium