[Effects of hydrocortisone and insulin on the electrokinetic potential of hepatocyte nuclei].
The electrokinetic potential of liver cell nuclei of rats after the in vivo separate and joint injection of hydrocortisone and insulin was determined. It was shown that the steroid induces a significant elevation of the value of electrokinetic potential while insulin does not change this parameter. An insignificant elevation of the potential by the joint action of the hormones was found, which apparently is indicative of the antagonism between hydrocortisone and insulin.
Gevorkian
E S
ES
Demirkhanian
L O
LO
Matinian
K S
KS
Gonian
S A
SA
D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects / Q000502:physiology; D004347:Drug Interactions; D005260:Female; D022781:Hepatocytes / Q000187:drug effects* / Q000648:ultrastructure; D006854:Hydrocortisone / Q000494:pharmacology*; D007328:Insulin / Q000494:pharmacology*; D008297:Male; D008564:Membrane Potentials; D051381:Rats
D007328:Insulin; D006854:Hydrocortisone