[The role of PKC isoforms in tumorigenicity and apoptotic cell death].
Protein kinase C comprises a family of at least 13 distinct serine/threonine kinase isoenzymes that have important actions in transmembrane signal transduction pathways and have been reported to regulate cell proliferation, differentiation, cell-to-cell interaction, cytoskeletal functions, gene transcription, apoptosis and drug resistance. The results of investigations show differential redistribution isoenzymes in each organ and their specific activity in determined diseases.
Zakład Chemii Klinicznej, Katedra Biochemii Farmaceutycznej, Akademia Medyczna im. K. Marcinkowskiego w Poznaniu.
M
M
Rybczyńska
K
K
Ksiazek
J
J
Kaczmarek
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism; D009369:Neoplasms / Q000503:physiopathology*; D011493:Protein Kinase C / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology
D007527:Isoenzymes; D011493:Protein Kinase C