The elusive cytostatic factor in the animal egg.
While animal eggs await fertilization, their cell cycle needs to be halted. The molecule responsible for this arrest--the cytostatic factor--was first described in 1971. But its identity was not revealed until 1989, and even now questions remain about this elusive factor.
Masui
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Department of Zoology, University of Toronto, 25 Harbord Street, Toronto, Ontario, Canada M5S 3G5. masui@zoo.utoronto.ca
D000818:Animals; D005260:Female; D008297:Male; D008954:Models, Biological; D009865:Oocytes / Q000502:physiology*; D017231:Proto-Oncogene Proteins c-mos / Q000378:metabolism / Q000502:physiology*; D011898:Ranidae; D013997:Time Factors
D017231:Proto-Oncogene Proteins c-mos