Lipodystrophy.
Congenital lipodystrophy is an uncommon autosomal recessive disorder that occurs mainly in females and is characterized by loss of subcutaneous fat, insulin-dependent diabetes mellitus, and masculinization due to defective metabolism of fat. Acquired lipodystrophy is now most commonly encountered in patients infected with HIV who take protease inhibitors. We present an illustrative case of lipodystrophy and review the presenting signs allowing for an accurate clinical diagnosis.
Helm
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TN
Department of Dermatology, Buffalo Medical Group, 6255 Sheridan Dr, Bldg B, Suite 208, Williamsville, NY 14221, USA.
Bisker
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E
Bergfeld
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WF
D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D008060:Lipodystrophy / Q000151:congenital* / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged
D007004:Hypoglycemic Agents; D007328:Insulin