Recent developments in glycine antagonists.
This paper covers the relevant scientific and patent literature published in the last two years concerning different classes of glycine antagonists and their potential application to therapeutic targets. Many of the molecules described here are approaching the final stages of clinical studies.
Antolini
M
M
Glaxo Wellcome SpA, Medicines Research Center, Via Fleming 4, 37100 Verona, Italy. fm20244@glaxowellcome.co.uk
Donati
D
D
Micheli
F
F
D000818:Animals; D002986:Clinical Trials as Topic; D005998:Glycine / Q000037:antagonists & inhibitors*; D018684:Glycine Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D009422:Nervous System Diseases / Q000188:drug therapy
D018684:Glycine Agents; D005998:Glycine