Chronic mucocutaneous candidiasis.
Chronic mucocutaneous candidiasis should be viewed as a spectrum of disorders in which the patients have persistent and/or recurrent candidiasis of the skin, nails and mucous membranes. Some of the conditions have genetic predispositions. A common immunologic abnormality is failure of the patient's T lymphocytes to produce cytokines that are essential for expression of cell-mediated immunity to Candida. Antifungal drugs are effective in clearing the infections, and treatments that restore cellular immunity have produced long term remissions.
Department of Medicine, University of Colorado Health Sciences Center, Denver 80206-1210, USA. ckirkpatrick@eri.uchsc.edu
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Kirkpatrick
D000935:Antifungal Agents / Q000627:therapeutic use*; D002178:Candidiasis, Chronic Mucocutaneous / Q000150:complications / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D006801:Humans; D007111:Immunity, Cellular; D007121:Immunocompetence; D007153:Immunologic Deficiency Syndromes / Q000150:complications
D000935:Antifungal Agents