[Immune status of patients with exudative otitis media before and after dimephosphon treatment].
General immunological reactivity and nonspecific resistance were studied in 50 patients with exudative otitis media (EOM) treated with oral dimephosphon (a course of 14 days). Blood serum immunoglobulins and lymphocyte subpopulations were measured with single radial immunodiffusion and flow cytofluorimetry, respectively. Multivariate correlation analysis of immune status made with a special computer program gave grounds to assert that dimephosphon promotes active reaction of immune system which results in positive changes in T-cell, humoral and neutrophilic-phagocytic links of immunity.
Svatko
L G
LG
Chepepnev
G V
GV
Rafailov
V V
VV
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D016827:CD8 Antigens / Q000187:drug effects* / Q000276:immunology*; D004804:Eosinophils / Q000187:drug effects / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000187:drug effects* / Q000276:immunology*; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology; D009943:Organophosphorus Compounds / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use*; D010034:Otitis Media with Effusion / Q000188:drug therapy* / Q000276:immunology*; D013997:Time Factors; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D016827:CD8 Antigens; D007070:Immunoglobulin A; D009943:Organophosphorus Compounds; C049638:dimephosphon