Molecular evidence of male-to-female sexual transmission of hepatitis C virus after vaginal and anal intercourse.
Hepatitis C virus (HCV) was transmitted from a chronic carrier to his female partner during unprotected anal and vaginal intercourse. Based on HVR1 and phylogenetic tree analysis, the couple had closely related isolates. These findings confirm sexual transmission of HCV without other risk factors.
Département de Virologie, Laboratoire Alphabio, 23 Rue de Friedland, Hôpital Ambroise Paré, 13006 Marseille, France. philippe.halfon@alphabio.fr
P
P
Halfon
H
H
Riflet
C
C
Renou
Y
Y
Quentin
P
P
Cacoub
D000328:Adult; D005260:Female; D016174:Hepacivirus / Q000235:genetics* / Q000302:isolation & purification; D006526:Hepatitis C / Q000635:transmission* / Q000821:virology; D006801:Humans; D008297:Male; D010802:Phylogeny; D012309:Risk-Taking; D017422:Sequence Analysis, DNA; D012725:Sexual Behavior; D015229:Sexually Transmitted Diseases, Viral / Q000821:virology*; D014764:Viral Proteins / Q000235:genetics
C400562:HVR1 protein, Hepatitis C virus; D014764:Viral Proteins