Minocycline induced autoimmune disease in rheumatoid arthritis: a missed diagnosis?
Minocycline is one of the major drugs for acne and is effective in rheumatoid arthritis (RA). We describe the first case of drug induced lupus secondary to the use of minocycline in a patient with RA. The dificulties of making this diagnosis as well as the implications for its pathogenesis are discussed.
Rheumatology and Rehabilitation Research Unit, University of Leeds, UK.
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H
Marzo-Ortega
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Misbah
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Emery
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy* / Q000276:immunology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008911:Minocycline / Q000008:administration & dosage / Q000009:adverse effects*; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D008911:Minocycline