Missed opportunities for congenital syphilis prevention in an urban southeastern hospital.
BACKGROUND
Despite recent declines in syphilis rates nationally, recent outbreaks suggest that prevention of congenital syphilis remains an ongoing public health problem.


OBJECTIVE
To identify missed opportunities for congenital syphilis prevention during prenatal care.


METHODS
Retrospective medical record review of 157 live birth or stillbirth deliveries that involved cases of congenital syphilis from Grady Memorial Hospital (Atlanta, GA).


RESULTS
The hospital congenital syphilis prevalence was 8.2 cases per 1,000 live births. Six percent of case patients were HIV positive. Opportunities for earlier maternal screening, treatment, or diagnosis were missed in 60% of case patients who received timely prenatal care. Congenital syphilis cases attributable to preventable missed opportunities were significantly more common among case patients with fewer prenatal visits (66% versus 28%, P = 0.01).


CONCLUSIONS
Provider efforts to reduce congenital syphilis in high-risk populations receiving prenatal care should focus on (1) screening patients at the first opportunity, at both the first prenatal visit and during the third trimester (i.e., 28 weeks); (2) performing on-site testing and same-day treatment; (3) providing appropriate treatment to infected women with penicillin allergy; (4) referring sex partners for treatment to prevent reinfection; and (5) screening all pregnant women attending emergency clinics.
Georgia Department of Human Resources, Division of Public Health, Atlanta, Georgia, USA. dlw7@cdc.gov
L
L
Warner
R W
RW
Rochat
R R
RR
Fichtner
B J
BJ
Stoll
L
L
Nathan
K E
KE
Toomey
D000328:Adult; D005260:Female; D005845:Georgia / Q000453:epidemiology; D006786:Hospitals, Urban; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D008403:Mass Screening; D011159:Population Surveillance; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D011295:Prenatal Care; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D013590:Syphilis, Congenital / Q000517:prevention & control* / Q000635:transmission; D014504:Urban Health