Cardiomyopathies in adolescents: dilated, hypertrophic, and restrictive.
Three major types of cardiomyopathies affect adolescents: dilated, hypertrophic, and restrictive. At the present time the etiologies of the majority of these cardiomyopathies in children remain elusive. Treatment of these diseases is generally directed toward improving symptoms, survival, myocardial performance, and hemodynamics. Most treatment strategies are extrapolated from studies in adults with these types of cardiomyopathies, although prospective, randomized therapeutic trials are currently underway in children. All three types of cardiomyopathy can be associated with a wide range of symptoms (from none to severe) and also are associated with sudden death. For those in whom medical management fails, heart transplantation is a therapeutic option with an excellent intermediate-term success rate.
Shaddy
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Department of Pediatrics, University of Utah School of Medicine, Heart Transplant Program, Primary Children's Medical Center, 100 North Medical Drive, Salt Lake City, Utah 84113, USA.
D000293:Adolescent; D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D002313:Cardiomyopathy, Restrictive / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D004562:Electrocardiography; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D011379:Prognosis