[Effect of Trusopt on normal intraocular pressure values in children].
The authors investigated a group of 406 healthy eyes of children aged 4 to 15 years to test the effect of the local carboanhydrase inhibitor TRUSOPT on natural previously assessed intraocular pressure. The measurements made by means of an air-puff contact-free tonometer NT 1100 NIDEK revealed a highly significant decline of intraocular pressure--from 16.08 mm Hg to 14.07 mm Hg on average in the whole group. The tolerance of the drug after a single administration caused no problems, no undesirable effect was recorded. This is the first and only report on the effect of TRUSOPT on normal intraocular pressure of the child eye reported in the literature in a statistically significant group. The authors are surprised by the fact that the possibility of favourable pharmacological treatment of child glaucoma with clinically widely used Trusopt is not used so far.
Klinika dĕtské oftalmologie LF MU a FN, Brno.
J
J
Rehůrek
R
R
Spicarová
J
J
Vancurová
D000293:Adolescent; D002257:Carbonic Anhydrase Inhibitors / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D013449:Sulfonamides / Q000494:pharmacology*; D013876:Thiophenes / Q000494:pharmacology*
D002257:Carbonic Anhydrase Inhibitors; D013449:Sulfonamides; D013876:Thiophenes; C062765:dorzolamide