Penicillin-resistant Streptococcus pneumoniae endocarditis: a case report and review.
Streptococcus pneumoniae has been a rare cause of endocarditis in the postantibiotic era. The emergence of antibiotic-resistant Pneumococcus species has been accompanied by isolated reports of penicillin-resistant S. pneumoniae (PRSP) endocarditis. We report a case of bivalvular PRSP endocarditis that was treated with vancomycin and trovafloxacin, and we review the literature on this topic.
Division of Infectious Diseases, Department of Medicine, Georgetown University Medical Center, Washington, DC 20007, USA.
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D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000188:drug therapy*; D005260:Female; D024841:Fluoroquinolones; D006801:Humans; D008875:Middle Aged; D009287:Naphthyridines / Q000627:therapeutic use; D010403:Penicillin Resistance; D011008:Pneumococcal Infections / Q000188:drug therapy*; D013296:Streptococcus pneumoniae / Q000187:drug effects*; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D009287:Naphthyridines; D014640:Vancomycin; C080163:trovafloxacin