Candida glabrata infection after total hip arthroplasty.
Only two incidents of periprosthetic infection due to Candida glabrata have been reported in the literature. We report successful treatment of a total hip replacement infected with this rare organism by a two-stage revision and synergistic combination antifungal therapy with Amphotericin B and 5-Flucytosine.
University Department of Orthopaedic Surgery, Western Infirmary, Glasgow, G11 6NT, UK.
N
N
Ramamohan
N
N
Zeineh
P
P
Grigoris
I
I
Butcher
D000368:Aged; D000666:Amphotericin B / Q000494:pharmacology / Q000627:therapeutic use; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D002175:Candida / Q000187:drug effects / Q000302:isolation & purification*; D002177:Candidiasis / Q000188:drug therapy*; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D005437:Flucytosine / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D016459:Prosthesis-Related Infections / Q000188:drug therapy* / Q000382:microbiology
D000935:Antifungal Agents; D000666:Amphotericin B; D005437:Flucytosine