Chronic mucocutaneous candidiasis.
Chronic mucocutaneous candidiasis should be viewed as a spectrum of disorders in which the patients have persistent and/or recurrent candidiasis of the skin, nails and mucous membranes. Some of the conditions have genetic predispositions. A common immunologic abnormality is failure of the patient's T lymphocytes to produce cytokines that are essential for expression of cell-mediated immunity to Candida. Antifungal drugs are effective in clearing the infections, and treatments that restore cellular immunity have produced long term remissions.
Kirkpatrick
C H
CH
Department of Medicine, University of Colorado Health Sciences Center, Denver 80206-1210, USA. ckirkpatrick@eri.uchsc.edu
D000935:Antifungal Agents / Q000627:therapeutic use*; D002178:Candidiasis, Chronic Mucocutaneous / Q000150:complications / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D006801:Humans; D007111:Immunity, Cellular; D007121:Immunocompetence; D007153:Immunologic Deficiency Syndromes / Q000150:complications
D000935:Antifungal Agents