The issue of prophylactic antibiotics prior to flexible cystoscopy.
OBJECTIVE
The aim of this study was to determine whether single-dose parenteral antibacterial therapy significantly alters the rate of infection in patients undergoing flexible cystourethroscopy.


METHODS
162 patients were studied prospectively having either received parenteral antibacterial chemoprophylaxis prior to flexible cystourethroscopy or not. Pre- and postprocedure mid stream samples of urine (MSSU) were obtained to objectively evaluate the presence of infection.


RESULTS
Gentamicin prophylaxis reduced the rate of post-cystoscopy-positive MSSUs from 21 to 5%.


CONCLUSIONS
The surprisingly high rate of infection after flexible cystoscopy was significantly reduced by a single dose of gentamicin.
Rané
A
A
Department of Urology, Frimley Park Hospital, Frimley, UK.
Cahill
D
D
Saleemi
A
A
Montgomery
B
B
Palfrey
E
E
D019072:Antibiotic Prophylaxis; D003558:Cystoscopy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D014552:Urinary Tract Infections / Q000209:etiology / Q000517:prevention & control*