MAO-A and MAO-B localisation in human lung and spleen.
Localisation of MAO-A and -B in human lung and spleen was studied by immunohistochemistry. The primary antibodies used were mouse monoclonal anti-human MAO-A (6G11/E1) and anti-human MAO-B (3F12/G10/2E3). Samples of lung and spleen were obtained from 6 routine autopsy cases. Both immunoreactivities showed a homogeneous distribution in lung, where all cell types had both MAO-A and -B staining. In spleen MAO-A and -B showed a very weak immunoreactivity, which was restricted to smooth muscle cells and reticular cells of the white pulp. These data represent the most comprehensive study of MAO-A and -B localisation in the two tissues.
Unitat de Bioquímica, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain.
M J
MJ
Rodríguez
J
J
Saura
E
E
Billett
C
C
Finch
N
N
Mahy
D000368:Aged; D000818:Animals; D004847:Epithelial Cells / Q000737:chemistry / Q000201:enzymology; D005260:Female; D006801:Humans; D008168:Lung / Q000737:chemistry* / Q000201:enzymology; D008297:Male; D051379:Mice; D008995:Monoamine Oxidase / Q000032:analysis*; D013154:Spleen / Q000737:chemistry* / Q000201:enzymology
D008995:Monoamine Oxidase