[A breast cancer patient with recurrence in the thoracic wall in whom a high-dose of toremifene was effective].
The patient was a 53-year-old female who presented with a primary complaint of reddening of the left precordial skin. She had undergone mastectomy for cancer of the left breast 12 years and 4 months earlier and had received endocrine chemotherapy including TAM as a postoperative adjuvant therapy. A diagnosis of thoracic wall recurrence was made by chest CT and pathological examination of skin biopsy specimens. Toremifene (TOR) was administrated at 120 mg/day, and PR was maintained for 8 months. Even after the condition became PD, the patient has retained adequate QOL with combination therapies including radiotherapy, and is still treated on an outpatient basis 3 years after the beginning of the treatment.
Ishida
K
K
Dept. of Surgery, Sumitomo Besshi Hospital.
Mori
H
H
Fujii
T
T
Kawashima
K
K
Hanaoka
T
T
Mihara
Y
Y
D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage*; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D020845:Selective Estrogen Receptor Modulators / Q000008:administration & dosage*; D013899:Thoracic Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D017312:Toremifene / Q000008:administration & dosage*
D018931:Antineoplastic Agents, Hormonal; D020845:Selective Estrogen Receptor Modulators; D017312:Toremifene