Serum creatine kinase level is a poor predictor of muscle function after injury.
Serum creatine kinase and dorsiflexion torque levels were measured in New Zealand White rabbits 1, 2, 7, 14, or 28 days after a single bout of eccentric exercise (n=26). No significant correlation was observed between creatine kinase activity and torque across time periods (P>0.15) and the regression relationship described only about 8% of the experimental variability. These data demonstrate that there exists a poor correlation between serum creatine kinase levels and skeletal muscle function after eccentric exercise.
Department of Hand Surgery, Sahlgrenska University Hospital, Göteborg, Sweden.
J
J
Fridén
R L
RL
Lieber
D000818:Animals; D015415:Biomarkers; D003402:Creatine Kinase / Q000097:blood*; D007527:Isoenzymes / Q000097:blood; D023421:Models, Animal; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000201:enzymology / Q000378:metabolism / Q000503:physiopathology*; D010080:Oxazoles / Q000494:pharmacology; D011817:Rabbits
D015415:Biomarkers; D007527:Isoenzymes; D010080:Oxazoles; C100282:mephenoxalone; D003402:Creatine Kinase