[Sensitivity to cow's milk proteins and gluten in children's allergic disease].
Aim of the study was the evaluation of sensitivity to cow's milk and gluten participation in children's allergic disease. Our studies were carried out in a group of 191 children, aged between 7 months and 18 years, with sensitivity to cow's milk proteins and gluten in type I and/or IV according to Gell and Coombs. Sensitivity to these allergens was confirmed in 88.4% of the 216 examined children with allergic disease. We showed a prevalent frequency of allergen specific T-cell responses in mechanism IV (in type IV - 79.58%, in type I - 10.99%, in I+IV - 9.42%). Evidence is presented that sensitivity to cow's milk proteins and gluten in I and IV Gell's and Coombs' mechanisms is more likely in small children and that it decreases with age.
Zaklad Immunologii, Instytut Matki i Dziecka, Kasprzaka 17a, 01-211, Warszawa, Poland. imid@imid.med.pl
M
M
Wawrzyniak
E
E
Bulawa
D000293:Adolescent; D000375:Aging / Q000276:immunology; D000917:Antibody Formation; D002648:Child; D002675:Child, Preschool; D005983:Glutens / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007223:Infant; D016269:Milk Hypersensitivity / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology*; D008894:Milk Proteins / Q000276:immunology; D011044:Poland / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D013601:T-Lymphocytes / Q000276:immunology*
D008894:Milk Proteins; D007073:Immunoglobulin E; D005983:Glutens