Future possibilities in the prevention of breast cancer: fat and fiber and breast cancer research.
The potential for a reduction in dietary fat or for an increase in dietary fiber to reduce breast cancer risk has been debated for some years. It is argued here that available research data, even though extensive, leave open hypotheses ranging from little or no potential to major public health potential for breast cancer prevention by means of these dietary maneuvers. Some elements of a research strategy for testing these and other dietary breast cancer prevention hypotheses are described.
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA. rprentic@fhcrc.org
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D000328:Adult; D000368:Aged; D000818:Animals; D016588:Anticarcinogenic Agents / Q000627:therapeutic use*; D001205:Ascorbic Acid / Q000627:therapeutic use; D001208:Asia / Q000208:ethnology; D001213:Asian; D001943:Breast Neoplasms / Q000453:epidemiology / Q000517:prevention & control*; D016022:Case-Control Studies; D015331:Cohort Studies; D004041:Dietary Fats / Q000009:adverse effects*; D004043:Dietary Fiber / Q000627:therapeutic use*; D004967:Estrogens / Q000378:metabolism; D005247:Feeding Behavior; D005260:Female; D005544:Forecasting; D006801:Humans; D008325:Mammary Neoplasms, Experimental / Q000209:etiology; D015201:Meta-Analysis as Topic; D051379:Mice; D008875:Middle Aged; D008954:Models, Biological; D019207:beta Carotene / Q000627:therapeutic use
D016588:Anticarcinogenic Agents; D004041:Dietary Fats; D004043:Dietary Fiber; D004967:Estrogens; D019207:beta Carotene; D001205:Ascorbic Acid