Detection of breast cancer after biopsy for false-positive screening mammography. An increased risk?
BACKGROUND
After false-positive screening for breast cancer, women are still at risk of developing breast cancer. In this study the incidence of breast cancer in a group of women who had a false-positive outcome is compared with the expected breast cancer incidence.


METHODS
Follow-up data of 188 women (mean age 58 years) with a false-positive screening result were collected and analysed for breast cancer development. The mean length of follow-up in the study was 7.4 years. The occurrence of breast cancer was compared to the expected incidence of breast cancer in an age-matched control population using figures from the local cancer registration.


RESULTS
The occurrence of breast cancer in the study population (n=7) was not significantly different from the expected incidence of breast cancer in the age-matched control group (n=5).


CONCLUSIONS
There is no relationship between false-positive findings during breast cancer screening and later development of breast cancer. Patients who do not have an increased risk of developing breast cancer (due to family history) should not be followed-up clinically, but should be returned to the screening programme.
Department of Surgery, University Medical Centre, Nijmegen, The Netherlands. rgroenendijk@ysl.nl
R P
RP
Groenendijk
M P
MP
Kochen
K C
KC
van Engelenburg
C
C
Boetes
L J
LJ
Strobbe
T J
TJ
Ruers
T
T
Wobbes
D000328:Adult; D000368:Aged; D001706:Biopsy; D001941:Breast Diseases / Q000175:diagnosis; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D005189:False Positive Reactions; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D012307:Risk Factors