Genetic counselling and genetic screening for Alzheimer's disease and other dementias.
Genetic and nongenetic factors have been identified to have roles in the etiology of dementia. Etiologic heterogeneity and genetic heterogeneity are recognized, especially for Alzheimer's disease which is the most common form of dementia. Asymptomatic individuals are increasingly requesting genetic services such as genetic counselling, predictive testing and screening for genetic risk factors. This paper provides an overview of the current knowledge about genetic counselling and genetic screening for dementia as well as guidelines for the physician.
Department of Medical Genetics, University of British Columbia, Vancouver, Canada.
A D
AD
Sadovnick
D000368:Aged; D000544:Alzheimer Disease / Q000235:genetics / Q000523:psychology*; D003704:Dementia / Q000235:genetics / Q000523:psychology*; D005817:Genetic Counseling; D005820:Genetic Testing; D006801:Humans; D008875:Middle Aged