[Pharmacological studies on Chinese bone extract granules].
The Chinese Bone Extract Granules could enhance the immunity of mice with spleen-deficiency, increase the serum calcium content of rats with bone loose, inhibit the gastrointestinal movement of mice with spleen-deficiency and improve the absorption of D-xylose in small intestine of rats with spleen-deficiency. The maximal tolerance dose for mice to take orally twice a day was greater than 50 g/kg. The subacute toxicologic test for 6 weeks of continuous feeding to rats did not show any obvious toxicity.
Anhui College of Traditional Chinese Medicine, Hefei 230038.
M
M
Dai
X
X
Zhi
D
D
Peng
Q
Q
Liu
D000818:Animals; D002118:Calcium / Q000378:metabolism; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D006968:Hypersensitivity, Delayed / Q000188:drug therapy; D007408:Intestinal Absorption / Q000187:drug effects; D008297:Male; D008419:Materia Medica / Q000494:pharmacology* / Q000633:toxicity; D051379:Mice; D010024:Osteoporosis / Q000378:metabolism*; D051381:Rats; D014994:Xylose / Q000378:metabolism; D016711:Yang Deficiency / Q000276:immunology* / Q000503:physiopathology
D008419:Materia Medica; D014994:Xylose; D002118:Calcium