Gene silencing: fleshing out the bones.
Genetic studies are revealing the pathway for RNA-mediated gene silencing. Short RNA molecules are the key, giving sequence specificity for RNA degradation and mediating communication within and between cells; these short RNAs are common to transcriptional and post-transcriptional silencing pathways.
CSIRO, Plant Industry, PO Box 1600 ACT 2601, Canberra, Australia. j.finnegan@pi.csiro.au
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Finnegan
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Wang
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Waterhouse
D000818:Animals; D002843:Chromatin / Q000737:chemistry; D019175:DNA Methylation; D020868:Gene Silencing; D063245:Plant Development; D010944:Plants / Q000235:genetics; D011487:Protein Conformation; D012313:RNA / Q000378:metabolism; D019076:Transgenes
D002843:Chromatin; D012313:RNA