Ocular significance of intraventricular haemorrhage in premature infants.
OBJECTIVE
To document ocular outcome in premature infants with intraventricular haemorrhages (IVH).


METHODS
68 preterm infants with IVH were examined.


RESULTS
Mean gestational age was 28.1 weeks (range 24-35). Mean birth weight was 1045.9 g (630-2240). Mean follow up was 54.6 months (6-150). IVH is graded from 1 to 4 based on the severity of haemorrhages. The incidence of ocular abnormalities was compared between low grade IVH (grade 1 and 2) and high grade IVH (grade 3 and 4). Of the 68 infants with IVH, ROP occurred in 33 infants (48.5%); 13 (43.3%) had low grade IVH; 20 (52.6%) had high grade IVH. Strabismus developed in 30 infants (44.1%); 14 (46.6%) had low grade IVH; 16 (42.1%) had high grade IVH. Infants with high grade IVH were at significant greater risk than infants with low grade IVH for the development of optic atrophy (31.5% v 16.6%), hydrocephalus (57.8% v 10%).


CONCLUSIONS
This study highlights the serious significance of all grades of IVH with the higher incidence of optic atrophy and hydrocephalus with high grade IVH.
O'Keefe
M
M
Kafil-Hussain
N
N
Flitcroft
I
I
Lanigan
B
B
D002543:Cerebral Hemorrhage / Q000150:complications* / Q000175:diagnosis; D002547:Cerebral Palsy / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D005128:Eye Diseases / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D009759:Nystagmus, Pathologic / Q000175:diagnosis / Q000209:etiology; D009896:Optic Atrophy / Q000175:diagnosis / Q000209:etiology; D011379:Prognosis; D012178:Retinopathy of Prematurity / Q000175:diagnosis / Q000209:etiology; D012307:Risk Factors; D012720:Severity of Illness Index; D013285:Strabismus / Q000175:diagnosis / Q000209:etiology; D015354:Vision, Low / Q000175:diagnosis / Q000209:etiology