Liver transplantation in a child with severe hypercholesterolaemia in Alagille syndrome.
BACKGROUND
Liver transplantation is a curative treatment modality in children with end stage liver disease in Alagille syndrome.


METHODS
We report a 3-year-old child with this condition who had severe hypercholesterolaemia, pruritus and extensive xanthomatosis.


METHODS
Liver transplantation was performed in this patient.


RESULTS
He recovered well with normalisation of his lipid profile. This procedure also resulted in resolution of the disfiguring xanthomatosis.
Quek
S C
SC
Department of Paediatrics, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074.
Aw
M
M
Quak
S H
SH
Prabhakaran
K
K
Tan
K C
KC
D016738:Alagille Syndrome / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D012720:Severity of Illness Index; D016896:Treatment Outcome