HoxA and HoxB cluster genes subdivide the digestive tract into morphological domains during chick development.
The digestive tract exhibits region-specific morphology and cytodifferentiation along the anteroposterior axis. We analyzed the spatial expression patterns of Hox genes belonging to the HoxA and HoxB cluster (Hoxa-4 approximately a-9, Hoxb-5 approximately b-9) in the developing chick digestive tract. The expression domains of these Hox genes correlated with morphological subdivision of the digestive tract along the anteroposterior axis.
Sakiyama
J
J
Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, 464-8602, Nagoya, Japan.
Yokouchi
Y
Y
Kuroiwa
A
A
D000818:Animals; D002454:Cell Differentiation; D002642:Chick Embryo; D004064:Digestive System / Q000196:embryology*; D004625:Embryo, Nonmammalian / Q000378:metabolism; D005895:Gizzard, Avian / Q000378:metabolism; D018398:Homeodomain Proteins / Q000096:biosynthesis*; D017403:In Situ Hybridization; D008648:Mesoderm / Q000378:metabolism; D010750:Phosphoproteins; D013997:Time Factors; D015534:Trans-Activators / Q000096:biosynthesis*
C489213:HOXA5 protein, human; C489126:HOXB5 protein, human; C490538:HOXB7 protein, human; C490669:HOXB8 protein, human; D018398:Homeodomain Proteins; C490537:Hoxb6 protein, mouse; D010750:Phosphoproteins; D015534:Trans-Activators; C088144:HoxA protein