[Separation and identification of the llungianin A and B from the root of Pimpinella thellungiana Wolff].
Two compounds were isolated from the roots of Pimpinella thellungiana wolff. On the basis of spectral analysis (UV, IR, MS, 1HNMR, 1H-1H COSY, 13CNMR, 1H-13C COSY, DEPT), they were identified as 2-(1-ethoxy-2-hydroxy) propyl-4-methoxyphenol(I); 2-(1-ethoxy-2-hydroxy) propyl-4-methoxyphenyl-2-methyl-butyrate (II). They are new compounds named the llungianin A and B. Pharmacological tests showed that they have some hypotensive effects.
Shaanxi Provincial Academy of Traditional Chinese Medicine and Materia Medica, Academy of Traditional Chinese Materia Medica, Xian 710003.
B L
BL
Qiao
C D
CD
Wang
C F
CF
Mi
F X
FX
Li
H L
HL
Shi
J
J
Takashima
D000959:Antihypertensive Agents / Q000737:chemistry / Q000302:isolation & purification; D019661:Apiaceae / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D015394:Molecular Structure; D010647:Phenyl Ethers / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D000959:Antihypertensive Agents; D004365:Drugs, Chinese Herbal; D010647:Phenyl Ethers; C425243:llungianin A; C425244:llungianin B