[Gd-BOPTA enhanced excretory MR urography without administration of diuretics].
OBJECTIVE
To evaluate the feasibility and clinical utility of Gd-BOPTA enhanced excretory magnetic resonance urography without additional administration of diuretics in correlation with conventional urography.


METHODS
15 preoperative patients with pelvic tumors were examined at 1.5 T using a breath-hold high-resolution 3D-FLASH sequence during first-pass as well as 5, 10, 15 minutes after i.v. injection of 0.05 mmol/kg BW Gd-BOPTA (MultiHance) without administration of diuretics. Post-processed coronal and multiplanar MIP reconstructions were compared to conventional excretory urography with regard to morphologic accuracy, anatomic variability, filling defects, cause and level of obstruction or compression, tumor visibility, and time-effectiveness by two independent radiologists.


RESULTS
Visualization of the urinary tract by MRU was comparable to conventional excretory urography in 14 of 15 cases. Caliceal fornices were better delineated on conventional urographies, whereas MRU was considered superior in the assessment of the inferior ureter sections, the urinary bladder and obstructive tumors, whose extents could be clearly marked out. Examination times of both techniques were comparable.


CONCLUSIONS
These first results show that non-diuretic Gd-BOPTA enhanced MRU is comparable to conventional excretory urography for the preoperative diagnosis of pelvic tumors. Further improvements of this technique seem possible by optimization of examination intervals and injection doses.
Institut für Klinische Radiologie Westfälische Wilhelms-Universität Münster. allkemp@uni-muenster.de
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T
Allkemper
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Tombach
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Heindel
D000328:Adult; D004232:Diuretics; D005682:Gadolinium; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008536:Meglumine / Q000031:analogs & derivatives; D008875:Middle Aged; D015588:Observer Variation; D009942:Organometallic Compounds; D010386:Pelvic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D015203:Reproducibility of Results; D014516:Ureteral Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D014567:Urography / Q000379:methods*; D014571:Urologic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery
D004232:Diuretics; D009942:Organometallic Compounds; C064572:gadobenic acid; D008536:Meglumine; D005682:Gadolinium