HoxA and HoxB cluster genes subdivide the digestive tract into morphological domains during chick development.
The digestive tract exhibits region-specific morphology and cytodifferentiation along the anteroposterior axis. We analyzed the spatial expression patterns of Hox genes belonging to the HoxA and HoxB cluster (Hoxa-4 approximately a-9, Hoxb-5 approximately b-9) in the developing chick digestive tract. The expression domains of these Hox genes correlated with morphological subdivision of the digestive tract along the anteroposterior axis.
Division of Biological Science, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, 464-8602, Nagoya, Japan.
J
J
Sakiyama
Y
Y
Yokouchi
A
A
Kuroiwa
D000818:Animals; D002454:Cell Differentiation; D002642:Chick Embryo; D004064:Digestive System / Q000196:embryology*; D004625:Embryo, Nonmammalian / Q000378:metabolism; D005895:Gizzard, Avian / Q000378:metabolism; D018398:Homeodomain Proteins / Q000096:biosynthesis*; D017403:In Situ Hybridization; D008648:Mesoderm / Q000378:metabolism; D010750:Phosphoproteins; D013997:Time Factors; D015534:Trans-Activators / Q000096:biosynthesis*
C489213:HOXA5 protein, human; C489126:HOXB5 protein, human; C490538:HOXB7 protein, human; C490669:HOXB8 protein, human; D018398:Homeodomain Proteins; C490537:Hoxb6 protein, mouse; D010750:Phosphoproteins; D015534:Trans-Activators; C088144:HoxA protein