Alcyonacean metabolites VII--chemical constituents of Lobophytum denticulatum and Lobophytum strictum of the Indian Ocean.
A rare cembranoid diterpene, (7E,11E.1 R,2S,3R,4R,l4S)-14-acetoxy-3,4-epoxycembra-7,11,15-triene-17,2-olide (1), was isolated from Lobophytum denticulatum and a new polyhydroxysterol, 7-hydroxyandamansterol (9) has been identified as peracetyl derivative from Lobophytum strictum. Several known polyhydroxysterols have also been isolated from these organisms. 1 exhibited moderate antibacterial activity.
Department of Chemistry, Sri Venkateswara University, Tirupati, India.
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Vanisree
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Subbaraju
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Bheemasankara Rao
D000818:Animals; D003063:Cnidaria / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D019156:Indian Ocean; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D013261:Sterols / Q000737:chemistry / Q000302:isolation & purification*
C427625:14-acetoxy-3,4-epoxycembra-7,11,15-triene-17,2-olide; C427624:7-hydroxyandamansterol; D004224:Diterpenes; D013261:Sterols