Advancement in biochemical assays in andrology.
Determination of markers of sperm function, accessory sex gland secretion and silent male genital tract inflammation is of considerable diagnostic value in the evaluation of male infertility. The introduction of biochemical tests into the analysis of male factor has the advantage that standardized assays with a coefficient of variation characteristic of clinical chemistry are performed, in contrast to biological test systems with a large variability. Biochemical parameters may be used in clinical practice to evaluate the sperm fertilizing capacity (acrosin, aniline blue, ROS), to characterize male accessory sex gland secretions (fructose, alpha-glucosidase, PSA), and to identify men with silent genital tract inflammation (elastase, C'3 complement component, coeruloplasmin, IgA, IgG, ROS).
Center of Dermatology and Andrology, Justus Liebig University, Giessen, Germany. Wolf.Bernhard.Schill@derma.med.uni-giessen.de
W B
WB
Schill
R
R
Henkel
D000176:Acrosin / Q000502:physiology; D015415:Biomarkers; D002843:Chromatin; D005632:Fructose / Q000378:metabolism; D005832:Genital Diseases, Male / Q000175:diagnosis; D006801:Humans; D007248:Infertility, Male / Q000175:diagnosis* / Q000209:etiology; D007249:Inflammation / Q000175:diagnosis; D019272:Leukocyte Elastase; D008297:Male; D011467:Prostate / Q000378:metabolism; D017382:Reactive Oxygen Species; D013094:Spermatozoa / Q000502:physiology; D000520:alpha-Glucosidases / Q000378:metabolism
D015415:Biomarkers; D002843:Chromatin; D017382:Reactive Oxygen Species; D005632:Fructose; D000520:alpha-Glucosidases; D000176:Acrosin; D019272:Leukocyte Elastase