[Adrenergic responses of arterial and venous vessels in the cat skeletal muscle in hypoxia and hypothermia].
In 12 anesthetized cats both hypoxia and hypothermia enhanced the shifts in arterial resistance against blood flow in response to noradrenaline and diminished the shifts in response to isoproterenol. Combination of both stress factors considerably weakened the adrenergic vasoconstriction and rather little affected the adrenergic vasodilatation. The findings suggest that protective effect of hypothermia against the background of a hypoxic stress might be a mechanism preventing disorders in the tissue metabolism.
Institute of Experimental Medicine, Russian Acad. Med. Sci, 197376, St. Petersburg, Acad. I. P. Pavlov St., 12.
M S
MS
Tabarov
D000322:Adrenergic Agonists / Q000494:pharmacology*; D000818:Animals; D001158:Arteries; D001775:Blood Circulation; D002415:Cats; D007036:Hypothermia, Induced; D007545:Isoproterenol / Q000494:pharmacology*; D018482:Muscle, Skeletal / Q000098:blood supply*; D009638:Norepinephrine / Q000494:pharmacology*; D010100:Oxygen / Q000494:pharmacology*; D014655:Vascular Resistance; D014662:Vasoconstrictor Agents / Q000494:pharmacology*; D014665:Vasodilator Agents / Q000494:pharmacology*; D014680:Veins
D000322:Adrenergic Agonists; D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents; D007545:Isoproterenol; D010100:Oxygen; D009638:Norepinephrine