Effect of concomitant or very early statin administration on in-hospital mortality and reinfarction in patients with acute myocardial infarction.
In a retrospective analysis, 66 patients identified as having received a statin drug within 24 hours of admission for acute myocardial infarction were matched 3:1 with a control group of 198 patients not treated with a statin agent. End points of in-hospital mortality and in-hospital reinfarction were significantly lower in the statin-treated group, pointing to a benefit from very early statin treatment in acute myocardial infarction.
Bybee
K A
KA
Department of Internal Medicine, Mayo Physician Alliance for Clinical Trials, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.
Wright
R S
RS
Williams
B A
BA
Murphy
J G
JG
Holmes
D R
DR
Kopecky
S L
SL
D000368:Aged; D004334:Drug Administration Schedule; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage*; D000960:Hypolipidemic Agents / Q000008:administration & dosage*; D008297:Male; D009203:Myocardial Infarction / Q000401:mortality* / Q000628:therapy; D012008:Recurrence; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D000960:Hypolipidemic Agents