Different red blood cell characteristics in a primitive agnathan (M. glutinosa) and a more recent teleost (O. mykiss) influence their strategies for blood CO2 transport.
This study examines how the different red blood cell (rbc) characteristics in two lower vertebrates, the phylogenetically primitive hagfish and a more recent teleost, the rainbow trout, influence their strategies for blood CO2 transport. Deoxygenation of the blood resulted in a significant increase in rbc CO2 content in hagfish, but there were no significant changes in the CO2 content of plasma or whole blood under these conditions. In contrast, deoxygenation increased the CO2 content of the rbc, plasma and whole blood in the trout. These results demonstrate that the Haldane effect is much less important for CO2 transport in the hagfish as compared to the trout. The relative importance of the rbc and plasma in blood CO2 transport were roughly similar in hagfish and trout and were very different from that previously documented in another primitive vertebrate, the lamprey. In trout, however, the role of the rbc in CO2 carriage was increased upon the addition of the beta-adrenergic agonist isoproterenol (10(-5) M) to the blood. Taken together, these results and those recently collected for lampreys demonstrate that changes in rbc characteristics during vertebrate evolution have probably resulted in several important transitions in the strategy for blood CO2 transport.
Tufts
B L
BL
Department of Biology, Queen's University, Kingston, Ontario, Canada. tuftsb@biology.queensu.ca
Vincent
C J
CJ
Currie
S
S
D000318:Adrenergic beta-Agonists / Q000494:pharmacology; D000818:Animals; D002245:Carbon Dioxide / Q000378:metabolism*; D004912:Erythrocytes / Q000187:drug effects / Q000502:physiology*; D006196:Hagfishes / Q000502:physiology*; D006863:Hydrogen-Ion Concentration; D007545:Isoproterenol / Q000494:pharmacology; D017686:Oncorhynchus mykiss / Q000502:physiology*; D010802:Phylogeny; D013045:Species Specificity
D000318:Adrenergic beta-Agonists; D002245:Carbon Dioxide; D007545:Isoproterenol