Septal scopolamine-systemic diazepam interaction in passive avoidance learning in rats.
The role of the septal region in passive avoidance (step-through) learning was studied by administering 15µg/0.5µl of scopolamine intraseptally to rats, together with an i.p. injection of 2mg/kg of diazepam to the same animals. The combined treatment provoked a severe impairment in retention of the learning situation, whereas animals which received either scopolamine or diazepam alone did not show any deficit.
Laboratoire C.E.B./E.T.C.A., 91710 Vert-Le-Petit, Avenue des facultés, 33405, Talence.
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Anglade
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Galey
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Chapouthier