Nonhomologous end-joining proteins are required for V(D)J recombination, normal growth, and neurogenesis.
Howard Hughes Medical Institute, Children's Hospital, Center for Blood Research, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
J M
JM
Sekiguchi
Y
Y
Gao
Y
Y
Gu
K
K
Frank
Y
Y
Sun
J
J
Chaudhuri
C
C
Zhu
H L
HL
Cheng
J
J
Manis
D
D
Ferguson
L
L
Davidson
M E
ME
Greenberg
F W
FW
Alt
D000818:Animals; D034961:Antigens, Nuclear; D017209:Apoptosis; D004265:DNA Helicases; D004260:DNA Repair; D004268:DNA-Binding Proteins / Q000172:deficiency / Q000235:genetics / Q000378:metabolism; D015322:Gene Rearrangement, B-Lymphocyte; D015329:Gene Rearrangement, T-Lymphocyte; D006128:Growth; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism; D000072200:Ku Autoantigen; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D009154:Mutation; D009420:Nervous System / Q000166:cytology / Q000196:embryology; D009687:Nuclear Proteins / Q000172:deficiency / Q000235:genetics; D010641:Phenotype; D011506:Proteins / Q000378:metabolism; D011995:Recombination, Genetic; D016159:Tumor Suppressor Protein p53 / Q000172:deficiency / Q000235:genetics
D034961:Antigens, Nuclear; D004268:DNA-Binding Proteins; D018398:Homeodomain Proteins; D009687:Nuclear Proteins; D011506:Proteins; C499308:Rag2 protein, mouse; D016159:Tumor Suppressor Protein p53; C064655:V(D)J recombination activating protein 2; C101467:XRCC4 protein, human; C064658:RAG-1 protein; D004265:DNA Helicases; C106893:XRCC5 protein, human; C000606509:Xrcc6 protein, human; C000606510:Xrcc6 protein, mouse; D000072200:Ku Autoantigen