Mining the draft human genome.
Now that the draft human genome sequence is available, everyone wants to be able to use it. However, we have perhaps become complacent about our ability to turn new genomes into lists of genes. The higher volume of data associated with a larger genome is accompanied by a much greater increase in complexity. We need to appreciate both the scale of the challenge of vertebrate genome analysis and the limitations of current gene prediction methods and understanding.
The European Bioinformatics Institute, Hinxton, Cambridge, UK. birney@ebi.ac.uk
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Bateman
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Hubbard
D000818:Animals; D016208:Databases, Factual; D005796:Genes; D015894:Genome, Human; D016045:Human Genome Project; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet