[Renal clear-cell carcinoma with X;1 translocation revealed by microscopic hematuria in a 23-year-old woman].
Microscopic hematuria is an uncommon inaugural sign of kidney tumors in young asymptomatic patients. Renal clear-cell carcinoma was diagnosed in a 23-year-old female explored for microscopic hematuria. Radical nephrectomy removed a 7-cm tumor without local extension. The cytogenic study of the tumor disclosed X;1 translocation. The patient also had IgA deficiency. Von Hippel-Lindau disease or a cytogenetic abnormality in the tumor are to be searched for in young adults with renal clear-cell carcinoma.
Clinique de Néphrologie, Hôpital d'Instruction des Armées du Val-de-Grace, Paris.
L
L
Vedrine
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C
Duvic
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P
Camparo
M
M
Herody
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P
Seris
G
G
Nedelec
D000328:Adult; D002292:Carcinoma, Renal Cell / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics*; D003582:Cytogenetics; D005260:Female; D006417:Hematuria / Q000209:etiology*; D006801:Humans; D017098:IgA Deficiency / Q000150:complications* / Q000175:diagnosis; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D009392:Nephrectomy; D014057:Tomography, X-Ray Computed; D014178:Translocation, Genetic / Q000235:genetics*; D014960:X Chromosome / Q000235:genetics*; D006623:von Hippel-Lindau Disease / Q000150:complications / Q000175:diagnosis / Q000235:genetics