Multisite comparison of reproducibility and recovery from the standard and ultrasensitive Roche AMPLICOR HIV-1 MONITOR assays.
Reproducibility and recovery from the standard and ultrasensitive Roche AMPLICOR HIV-1 MONITOR kits were compared in 19 laboratories. The results were generally similar, but the consistently low level of recovery from the ultrasensitive assay in one laboratory points to the need to include external controls in order to track assay performance.
New England Research Institutes, Inc., Watertown, Massachusetts 02472, USA. donb@neri.org
D J
DJ
Brambilla
S
S
Granger
C
C
Jennings
J W
JW
Bremer
D015658:HIV Infections / Q000175:diagnosis* / Q000821:virology; D015497:HIV-1 / Q000502:physiology*; D006801:Humans; D007389:Internal-External Control; D007753:Laboratories / Q000592:standards; D011786:Quality Control; D012367:RNA, Viral / Q000097:blood*; D011933:Reagent Kits, Diagnostic / Q000592:standards; D015203:Reproducibility of Results; D019562:Viral Load
D012367:RNA, Viral; D011933:Reagent Kits, Diagnostic