Case report: acute tumour lysis syndrome.
BACKGROUND
Acute tumour lysis syndrome (ATLS) is a potentially lethal but preventable complication of oncological treatment.


METHODS
We report a case of a patient with Burkitt's leukaemia who developed ATLS after treatment with chemotherapy.


METHODS
Standard preventive measures using aggressive hydration, urine alkalinisation and uricosuric agents were instituted before chemotherapy.


RESULTS
However in spite of adequate measures, the patient succumbed to the sequelae of ATLS.


CONCLUSIONS
It is therefore important to identify patients who are at a high risk of developing ATLS so that additional measures can be taken to prevent it from occurring.
Department of Haematology, Singapore General Hospital, 1 Hospital Drive, Singapore 169608.
C T
CT
Chuah
L C
LC
Lim
D000208:Acute Disease; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects*; D002051:Burkitt Lymphoma / Q000175:diagnosis* / Q000188:drug therapy*; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000009:adverse effects; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D015275:Tumor Lysis Syndrome / Q000209:etiology* / Q000628:therapy; D014750:Vincristine / Q000008:administration & dosage / Q000009:adverse effects
D014750:Vincristine; D003520:Cyclophosphamide