An isopimarane diterpene from Euphorbia ebracteolata Hayata.
From the ethanolic extract of the roots of Euphorbia ebracteolata Hayata four compounds were isolated. They are 24-methylenecycloartanone, tirucallol, procesterol and a new isopimarane diterpene, namely yuexiandajisu C. The structure of yuexiandajisu C was elucidated by spectral analysis. The bioassay in vitro showed yuexiandajisu C exhibited immunomodulatory activity.
Shanghai Institute of Materia Medica, Chinese Academy of Sciences.
Z H
ZH
Xu
G W
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Qin
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Xu
D000276:Adjuvants, Immunologic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001402:B-Lymphocytes / Q000187:drug effects; D002942:Circular Dichroism; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000276:Adjuvants, Immunologic; D004224:Diterpenes; C426085:yuexiandajisu C