Thoracic esophageal cancer recurred later than 2 years after esophagectomy with extended lymphadenectomy.
OBJECTIVE
Although the majority of recurrence was found in 2 years after esophagectomy, esophageal cancer could recur lately. To find efficient follow up, the patients were compared by periods of recurrence detected.


METHODS
Esophagectomized 227 patients were subjected. Median follow up period was 1289 days. The disease recurred in 84 patients (Group A) in 2 years after surgery and in 17 (Group B) lately. Clinicopathological factors were compared between these 2 groups.


RESULTS
There was no difference in background and clinicopathological factors, except Group A was at significantly advanced stage than B. The most common pattern of recurrence was hematogeneous in Group A, whereas lymphatic in Group B, which was significantly different. In Group B, survival rate of patients detected by lymphatic recurrence, which responded to radiation, was higher than that detected by hematogeneous one.


CONCLUSIONS
To prolong survival, the patients should be carefully followed up later than 2 years after surgery with regard for lymphatic recurrence.
Osugi
H
H
Second Department of Surgery, Osaka City University Medical School, Osaka, Japan.
Higashino
M
M
Takada
N
N
Takemura
M
M
Kinoshita
H
H
D000368:Aged; D004938:Esophageal Neoplasms / Q000601:surgery*; D016629:Esophagectomy; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D013899:Thoracic Neoplasms / Q000601:surgery*