Osteoclastic giant cell tumor of the pancreas: case report and literature review.
An unusual case of a 40-year-old woman seeking treatment for a 10-cm cystic neoplasm of the pancreas is described. Imaging revealed a large proteinaceous, fluid-filled cyst with a mural nodule. Laparotomy was successful with en bloc resection. Pathologic examination revealed a neoplastic mucinous epithelial tumor with an abundance of multinucleated tumor giant cells. This presentation is consistent with literature reports of an osteoclastic-type giant-cell tumor of the pancreas. The natural history, pathologic evaluation, and clinical implications of this rare neoplasm are discussed with reference to published reports.
Leighton
C C
CC
Division of Radiation Oncology, University of Western Ontario, London Regional Cancer Centre, Canada. chris.leighton@lrcc.on.ca
Shum
D T
DT
D000328:Adult; D005260:Female; D005870:Giant Cell Tumors / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D010010:Osteoclasts / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery*