[Neuraminidase inhibitor].
Amantadine, effective to influenza A virus, is now widely used in Japan. Recently new anti-influenzal agents, neuramidase inhibitor has been developed. Both Zanamivir (inhaled type) and Oseltamivir(oral use), are proved to be effective in treatment of influenza A and B. Mechanism of action on influenza virus, dosage, side effects of the anti-influenza agents are described. Clinicians expect to medicate to influenza with the agents as soon as possible.
Kaji
M
M
Kurume University Medical Center.
D000081:Acetamides / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use*; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D006146:Guanidines; D006801:Humans; D009980:Influenza A virus; D009981:Influenza B virus; D007251:Influenza, Human / Q000188:drug therapy*; D009439:Neuraminidase / Q000037:antagonists & inhibitors*; D053139:Oseltamivir; D011714:Pyrans; D012794:Sialic Acids / Q000627:therapeutic use*; D053243:Zanamivir
D000081:Acetamides; D000998:Antiviral Agents; D004791:Enzyme Inhibitors; D006146:Guanidines; D011714:Pyrans; D012794:Sialic Acids; D053139:Oseltamivir; D009439:Neuraminidase; D053243:Zanamivir