Anti-inflammatory effect of (+)-pinitol.
In the carrageenin-induced paw oedema in rats, (+)-pinitol (2.5-10 mg/kg, i.p.), isolated from Abies pindrow leaves, showed a significant anti-inflammatory effect, the highest dose being comparable to phenylbutazone (100 mg/kg, i.p.).
Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, -221005, Varanasi, India.
R K
RK
Singh
B L
BL
Pandey
M
M
Tripathi
V B
VB
Pandey
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002351:Carrageenan; D004305:Dose-Response Relationship, Drug; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control*; D005260:Female; D007294:Inositol / Q000031:analogs & derivatives / Q000494:pharmacology*; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology; D018515:Plant Leaves; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar
D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; C021730:pinitol; D007294:Inositol; D002351:Carrageenan