Is there an FSH-releasing factor?
A thorough understanding of the factors that regulate the secretion of FSH is critical for the development of efficient methods for fertility regulation. The purpose of this review is to evaluate what is currently known about the existence of FSH-releasing factor(s). It considers the obstacles encountered in understanding the control of FSH secretion, current knowledge of the nature of FSH secretion and the mechanisms involved in controlling FSH secretion, the arguments that have been posed against the need for an FSH-releasing factor and finally the evidence available to date supporting the existence of FSH-releasing factor(s).
Department of Pediatrics and the Reproductive Sciences Program, University of Michigan, Ann Arbor, MI 48109, USA. vasantha@umich.edu
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Padmanabhan
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McNeilly
D000818:Animals; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone / Q000502:physiology; D006706:Homeostasis; D006801:Humans; D007031:Hypothalamus / Q000502:physiology; D007986:Luteinizing Hormone / Q000378:metabolism; D010902:Pituitary Gland / Q000502:physiology
D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone