Transcriptional regulation in lymphocytes.
Lymphocytes have been used to investigate many cellular processes, including lineage commitment, differentiation, proliferation and apoptosis. The transcription factors that mediate these processes are often expressed broadly in many cell types. The emerging theme is one of cell-type-specific regulation, affecting not only the functional activation of transcription factors but also their access to appropriate regions of DNA.
Department of Pathology, Harvard Medical School and The Center for Blood Research, 200 Longwood Avenue, Boston, Massachusetts 02115, USA. okamura@cbr.med.harvard.edu
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D000818:Animals; D005786:Gene Expression Regulation; D015321:Gene Rearrangement; D005803:Genes, Immunoglobulin / Q000235:genetics; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism*; D014157:Transcription Factors / Q000235:genetics; D014158:Transcription, Genetic
D014157:Transcription Factors