Empirical treatment of sepsis in neutropenic patients.
Mortality associated with febrile neutropenia has dramatically decreased over the last three decades; a pivotal role has been played by the concept of hospital-based empirical therapy with broad-spectrum combinations of antibiotics. Nevertheless, there is evidence that a subgroup of patients with febrile neutropenia might benefit from less aggressive treatments.
Klastersky
J
J
Service de Médecine et Laboratoire d'Investigation Clinique, Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, rue Héger-Bordet 1, 1000 Bruxelles, Belgium.
D000553:Ambulatory Care; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D009503:Neutropenia / Q000150:complications / Q000188:drug therapy*; D010343:Patient Admission; D018579:Patient Selection; D018805:Sepsis / Q000150:complications / Q000188:drug therapy*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents