Spinal cord involvement in primary angiitis of the central nervous system: a report of two cases.
We report two patients with suspected primary angiitis of the CNS who underwent serial contrast-enhanced MR imaging of the spinal cord. MR abnormalities were multiple and enhancing, and located within the cervical and thoracic cord. Brain MR findings and brain biopsy specimens were positive for primary angiitis of the CNS. On follow-up MR studies, obtained after steroid and immunosuppressive therapy, a significant decrease in the number and size of the enhancing and nonenhancing abnormalities was observed, along with clinical improvement. Numerous small and enhancing abnormalities with a primarily posterior location, seen at the onset of the disease and resolved on follow-up studies, may be considered suggestive of a diagnosis of primary angiitis of the CNS.
Campi
A
A
Department of Neuroradiology, Scientific Institute and University San Raffaele, Milan, Italy.
Benndorf
G
G
Martinelli
V
V
Terreni
M R
MR
Scotti
G
G
D000328:Adult; D001706:Biopsy; D001921:Brain / Q000473:pathology; D002490:Central Nervous System / Q000098:blood supply*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013116:Spinal Cord / Q000473:pathology*; D014657:Vasculitis / Q000175:diagnosis* / Q000473:pathology