[Imaging of breast tumors using MR elastography].
OBJECTIVE
Imaging of breast tumors using MR-Elastography.


METHODS
Low-frequency mechanical waves are transmitted into breast-tissue by means of an oscillator. The local characteristics of the mechanical wave are determined by the elastic properties of the tissue. By means of a motion-sensitive spin-echo-sequence these waves can be displayed within the phase of the MR image. Subsequently, these images can be used to reconstruct the local distribution of elasticity. In-vivo measurements were performed in 3 female patients with malignant tumors of the breast.


RESULTS
All patients tolerated the measurement set-up without any untoward sensation in the contact area of skin and oszillator. The waves completely penetrated the breast, encompassing the axilla and regions close to the chest wall. All tumors were localized by MRE as structures of markedly stiffer tissue when compared to the surrounding tissue. Furthermore, in one patient, a metastasis in an axillary lymph node was detected. In all patients, local regions of increased elasticity were found in the remaining parenchyma of the breast, which, however, did not reach the high levels of elasticity found in the tumors.


CONCLUSIONS
MRE is an imaging modality enabling adjunct tissue differentiation of mammary tumors.
Lorenzen
J
J
Abteilung für Röntgendiagnostik, Radiologische Klinik, Universitätskrankenhaus-Eppendorf, Hamburg.
Sinkus
R
R
Schrader
D
D
Lorenzen
M
M
Leussler
C
C
Dargatz
M
M
Röschmann
P
P
D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000175:diagnosis; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008327:Mammography; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014055:Tomography, Emission-Computed