Study of immunotropic activities of Bacillus subtilis as the basis of anti-scleroma probiotics.
Presence of influence of Bacillus subtilis during peroral and parenteral administration upon the laboratory animals' immune system has been studied. Absence of immuno-depressing action of the bacillus culture under study has been presented with the help of assessment tests on the humoral response to the thymus-dependent antigen: creation of the antibodies, and the delayed-onset hypersensitivity reaction. An insignificant stimulating effect has been revealed under execution of the reaction of the delayed-onset hypersensitivity as a result of B. subtilis application. The obtained data confirm the prospects of application of the B. subtilis strain as a basis of the anti-scleroma probiotics.
Boiko
N V
NV
Uzhhorod State University, 46 Pidgirna St., Uzhgorod, 88000, Ukraine.
Lysetska
M V
MV
Arkadiev
V G
VG
Maksimov
Y M
YM
Danylenko
V P
VP
D000284:Administration, Oral; D000818:Animals; D000917:Antibody Formation; D001412:Bacillus subtilis / Q000276:immunology*; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007263:Infusions, Parenteral; D051379:Mice; D019936:Probiotics / Q000008:administration & dosage / Q000494:pharmacology*; D012226:Rhinoscleroma / Q000517:prevention & control