Extubation failure in a large pediatric ICU population.
OBJECTIVE
To review a large population of children receiving mechanical ventilation to establish a baseline rate of extubation success and failure and to identify those characteristics that place a patient at greater risk of failing planned extubation.


METHODS
Retrospective chart review.


METHODS
University-affiliated children's hospital with a 20-bed pediatric ICU.


METHODS
All 632 patients receiving mechanical ventilation during the 2-year period from July 1, 1996, to June 30, 1998.


METHODS
Patients receiving mechanical ventilation were identified via a computerized database. Charts were reviewed of all patients who were reintubated within 72 h of extubation.


RESULTS
There were 548 planned extubation events, of which 521 were successful. Twenty-seven patients failed planned extubation at least once; only the first attempt at extubation was included in the analysis. The failure rate of planned extubations was 4.9%. Including only patients who had received mechanical ventilation for > 24 h before extubation, the failure rate was 6.0%. For patients intubated > 48 h, the failure rate was 7.9%. The patients who failed extubation were found to be significantly younger and to have received mechanical ventilation longer than those who succeeded, in both the analysis of all patients receiving mechanical ventilation and the subgroup of those receiving mechanical ventilation > 24 h. When only patients who had received mechanical ventilation for > 48 h were analyzed, the difference in age was no longer significant, but the duration of ventilation before extubation was still significantly longer for those who failed.


CONCLUSIONS
We determined the overall failure rate of planned extubations in a large population of pediatric patients to be 4.9%. Those patients who were younger and had received mechanical ventilation longer were more at risk for extubation failure.
Edmunds
S
S
Division of Pediatric Critical Care, Mattel Children's Hospital, UCLA Medical Center, Los Angeles, CA 90024-1783, USA.
Weiss
I
I
Harrison
R
R
D016022:Case-Control Studies; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D015278:Intensive Care Units, Pediatric; D007442:Intubation, Intratracheal; D012121:Respiration, Artificial; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D017211:Treatment Failure; D015300:Ventilator Weaning