[Diagnostic and prognostic significance of the blood neutrophils functional activity in patients with an acute destructive pancreatitis].
The neutrophils functional state was studied in 101 patients with an acute destructive pancreatitis (DP), complicated by parapancreatitis, in 20 patients with edematic pancreatitis and in 25 healthy persons using cytochemical reactions with determination of the enzymes activity of alkaline phosphatase, myeloperoxidase, and also of lysosomic-cation proteins, phospholipids and glycogen. The enzymatic contents of neutrophils changes in acute period of destructive pancreatitis (DP) are causing their function inhibition, promoting the infection complications occurrence. The neutrophils functional activity indexes may be used in early diagnosis and prognostication of the DP course.
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D006098:Granulocytes / Q000378:metabolism; D006801:Humans; D009504:Neutrophils / Q000378:metabolism; D019283:Pancreatitis, Acute Necrotizing / Q000097:blood* / Q000175:diagnosis* / Q000601:surgery; D011379:Prognosis; D013997:Time Factors; D016896:Treatment Outcome