[Alkaloids in Sophora alopecuroides seed and relevant tests for activity].
Seven alkaloids were isolated from the seed of Sophora alopecuroides and identified to be oxymatrin, oxysophocarpine, cytisine, matrine, sophocarpine, sophoridine and nicotine respectively by comparing chromactographic and spectral characteristics with authentic known compounds. Nicotine was isolated from Sophora for the first time. The activity of extracts and alkaloids against cancer, virus, dermatophytes and bacteria was carried out in vitro.
Zhang
L
L
Beijing University of Traditional Chinese Medicine, Beijing 100029.
Li
G
G
Houghton
P J
PJ
Jackson
S
S
Twentyman
P R
PR
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D003553:Cystine / Q000737:chemistry / Q000302:isolation & purification; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D007887:Fabaceae / Q000737:chemistry*; D008175:Lung Neoplasms / Q000473:pathology; D009538:Nicotine / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal; D011807:Quinolizines; D012639:Seeds / Q000737:chemistry; D014407:Tumor Cells, Cultured / Q000187:drug effects; D000093842:Matrines
D000470:Alkaloids; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D011807:Quinolizines; D003553:Cystine; C046246:oxysophocarpine; D009538:Nicotine; C037573:oxymatrine; D000093842:Matrines