Affective symptomatology in schizophrenia: a risk factor for tardive dyskinesia?
Affective symptomatology has repeatedly been suggested to confer susceptibility to tardive dyskinesia (TD). In our sample of 174 schizophrenic patients a history of depressive symptoms was not associated with the occurrence of TD, whereas manic symptomatology was significantly associated with the absence of TD. Thus, our data suggest that affective symptomatology cannot unambiguously be considered to predispose to TD.
Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, Germany. schulze@uchicago.edu
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Schulze
D J
DJ
Müller
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Krauss
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K
Marwinski
A O
AO
Maroldt
A
A
Novo Y Fernández
R
R
Fimmers
T
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Held
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Maier
M M
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Nöthen
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Rietschel
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D019964:Mood Disorders / Q000150:complications* / Q000175:diagnosis* / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D012559:Schizophrenia / Q000150:complications* / Q000188:drug therapy; D012720:Severity of Illness Index
D014150:Antipsychotic Agents