Role of dobutamine echocardiography in detection of myocardial viability for predicting outcome after revascularization in ischemic cardiomyopathy.
Coronary artery disease is the most common cause of heart failure in the Western world. Compared with medical therapy, surgical revascularization has been shown to improve survival rates in nonrandomized trials in patients with ischemic cardiomyopathy. However, perioperative mortality is high in this group of patients who do not demonstrate significant viable myocardium. Echocardiography during dobutamine infusion has been shown to reliably detect viable myocardium. Several studies have demonstrated its ability to provide high predictive value for recovery of both regional and global left ventricular function after revascularization. Indeed, nonrandomized studies also have indicated its value in predicting which patients with severe ischemic cardiomyopathy are likely to survive after revascularization. Dobutamine stress echocardiography has emerged as a safe and valuable technique for the assessment of myocardial viability and for the selection of patients for revascularization.
Department of Cardiovascular Medicine, Northwick Park Hospital and Institute for Medical Research, Harrow, United Kingdom. roxy.senior@virgin.net
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Senior
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Lahiri
D002316:Cardiotonic Agents; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery*; D004280:Dobutamine; D004452:Echocardiography / Q000379:methods*; D006801:Humans; D009204:Myocardial Revascularization; D011237:Predictive Value of Tests
D002316:Cardiotonic Agents; D004280:Dobutamine