Treatment of methicillin-resistant Staphylococcus epidermidis infection following repair of an ulnar fracture and humeroradial joint luxation in a horse.
A 27-month-old Rocky Mountain Horse was examined because of a fracture of the proximal portion of the ulna and luxation of the humeroradial joint (Monteggia fracture). Open reduction was performed, using a mechanical distractor, and the ulnar fracture was stabilized by application of a bone plate and screws. After surgery, the horse developed an infection of the surgical site, and bacterial culture of fluid from the surgical site yielded a pure growth of methicillin-resistant Staphylococcus epidermidis susceptible to oxytetracycline, erythromycin, rifampin, and vancomycin. Treatment with oxytetracycline did not result in a favorable clinical response. Therefore, the horse was treated systemically with vancomycin and rifampin, and vancomycin-impregnated polymethyl methacrylate beads were implanted at the surgical site. Six months after surgery, the horse was sound at a walk or trot, and bony union was evident on radiographs of the elbow joint.
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706-1102, USA.
S S
SS
Trostle
C L
CL
Peavey
D S
DS
King
F A
FA
Hartmann
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004551:Elbow Joint / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery; D005260:Female; D006734:Horse Diseases / Q000188:drug therapy* / Q000382:microbiology; D006736:Horses; D004204:Joint Dislocations / Q000601:surgery / Q000662:veterinary*; D016106:Methicillin Resistance; D011859:Radiography; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D013212:Staphylococcus epidermidis / Q000187:drug effects*; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D014458:Ulna Fractures / Q000601:surgery / Q000662:veterinary*; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D014640:Vancomycin