Regulation of gene expression by GC-rich DNA cis-elements.
GC-rich DNA cis elements are important transcriptional regulatory elements present in the promoter, enhancer and locus control regions of many eukaryotic genes from several species. This review attempts to examine the structure, function and biological significance of GC-rich cis -regulatory elements and their cognate binding proteins, with a view to understanding their role in regulation of gene expression.
Department of Biochemistry, Stellenbosch University, Stellenbosch 7602, South Africa. JHap@maties.sun.ac.za
J P
JP
Hapgood
J
J
Riedemann
S D
SD
Scherer
D000818:Animals; D002453:Cell Cycle / Q000235:genetics; D002843:Chromatin / Q000378:metabolism; D003596:Cytosine; D019175:DNA Methylation; D004268:DNA-Binding Proteins / Q000378:metabolism; D004742:Enhancer Elements, Genetic; D005786:Gene Expression Regulation; D006147:Guanine; D006801:Humans; D011401:Promoter Regions, Genetic; D014158:Transcription, Genetic
D002843:Chromatin; D004268:DNA-Binding Proteins; D006147:Guanine; D003596:Cytosine