[The value of lipofuscin determination in blood at the pathophysiologic clinic--literature review].
Lipofuscin is a conjugated Schiff base delivered from reaction of malonylodialdehyde with proteins, amino acids and phosphatidylethanolamines. It emits yellow-green autofluorescence in ultraviolet light. It is believed to be one of the parameters of oxidation stress in vivo. Increased amount of lipofuscin in the blood has been found in uremia, diabetes, aging process, adult respiratory distress syndrome and multiple organ failure.
I Katedry i Kliniki Chirurgii Ogólnej i Transplantacyjnej Slaskiej Akademii Medycznej w Katowicach.
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Chmiel
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Kuśmierski
D000328:Adult; D000375:Aging / Q000097:blood; D000818:Animals; D015415:Biomarkers / Q000097:blood; D003920:Diabetes Mellitus / Q000097:blood; D006801:Humans; D008062:Lipofuscin / Q000097:blood*; D009102:Multiple Organ Failure / Q000097:blood; D018384:Oxidative Stress / Q000502:physiology*; D012128:Respiratory Distress Syndrome / Q000097:blood; D014511:Uremia / Q000097:blood
D015415:Biomarkers; D008062:Lipofuscin