Harm reduction theories and strategies for control of human immunodeficiency virus: a review of the literature.
OBJECTIVE
To provide a comprehensive review of the literature on harm reduction theories and strategies related primarily to licit and illicit drug use.


BACKGROUND
Although human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) disease transmission is well understood, it continues to spread, particularly among injection drug users (IDUs). Despite early indications that HIV would be contained within the IDU community, it is spreading to non-IDU sexual partners and to children of IDUs, threatening a more widespread epidemic.


METHODS
An examination of research studies and theoretical writings including reviews and policy papers published in English between 1990 and 2000.


RESULTS
Harm reduction does not seek to eliminate drug use; it focuses on minimizing the personal and social harms and costs associated with drug use and spread of HIV. It seeks to ameliorate conditions surrounding drug use responsible for the spread of HIV in the IDU community: unequal access to health services; sharing of infected needles; racial and social discrimination; poverty; exposure to street violence; inadequate housing; lack of employment; poor general or mental health and other demographic and social determinants. Some controversial harm reduction strategies are described: methadone maintenance programmes, illegal drugs dispensing under controlled conditions, needle exchanges, HIV testing, vein maintenance, safe-sex and would-care programmes.


CONCLUSIONS
The main challenge is to get IDUs to protect themselves against HIV when suffering physical and social privations and addiction needs. Diverse perspectives on harm reduction are problematic with consequences for success of drug use initiatives. Practical, ethical and theoretical complexities exist but further research is needed to build support for a harm-reduction orientation in practice and policy formulation.
Hilton
B A
BA
University of British Columbia, Vancouver, Canada. hilton@nursing.ubc.ca
Thompson
R
R
Moore-Dempsey
L
L
Janzen
R G
RG
D003159:Community-Institutional Relations; D017281:Cost of Illness; D015658:HIV Infections / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control*; D006291:Health Policy; D006293:Health Promotion; D006297:Health Services Accessibility / Q000592:standards; D006304:Health Status; D006801:Humans; D008403:Mass Screening; D008962:Models, Theoretical; D016485:Needle Sharing / Q000009:adverse effects; D010686:Philosophy, Medical; D011203:Poverty / Q000517:prevention & control; D011287:Prejudice; D011330:Prisons; D015980:Public Health Practice; D012307:Risk Factors; D016320:Substance Abuse Treatment Centers; D015819:Substance Abuse, Intravenous / Q000150:complications* / Q000453:epidemiology / Q000517:prevention & control*