Relation of soluble and platelet P-selectin to early outcome in patients with acute myocardial infarction after thrombolytic therapy.
Pre- and post-treatment platelet and soluble P-selectin were measured in a group of patients enrolled in the GUSTO-III study and were correlated with clinical outcomes. A peak in soluble P-selectin levels at 3 hours after thrombolytic therapy and lower baseline platelet P-selectin were associated with successful thrombolysis.
Gurbel
P A
PA
Sinai Hospital, Baltimore, Maryland 21215, USA. pgurbel@sinai-balt.com
O'Connor
C M
CM
Dalesandro
M R
MR
Serebruany
V L
VL
D000328:Adult; D001792:Blood Platelets / Q000378:metabolism; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000097:blood / Q000188:drug therapy*; D019007:P-Selectin / Q000097:blood*; D012995:Solubility; D015912:Thrombolytic Therapy
D019007:P-Selectin