[Increased radiosensitivity after irradiation of lymphocytes low adaptive doses].
The variability of blood lymphocyte reaction on the adaptive irradiation (0.05 Gy at first, then 1.0 Gy 5 h later) was investigated by micronuclei assay. Blood samples were obtained from 700 children. It was shown that in all groups studied there were children with enhanced radiosensitivity ("radiosensitivity syndrome"-RS) after exposure to adaptive low dose of radiation. The radiosensitivity syndrome occurred more often in groups of ill children; part of them was characterized by the enhanced blood content of immunoglobulin E, enhanced level of T helpers and T suppressors. A high spontaneous level of lymphocytes with micronucleus is a factor of radiosensitivity formation. The possible factors resulted in radiosensitivity syndrome are discussed.
Pelevina
I I
II
Semenov Institute of Chemical Physics, Russion Academy of Sciences, Moscow, 117977 Russia.
Aleshchenko
A V
AV
Gotlib
V Ia
VIa
Kudriashova
O V
OV
Noskin
L A
LA
Semenova
L P
LP
Sotnikova
E N
EN
Serebrianyĭ
A M
AM
D000220:Adaptation, Biological; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007223:Infant; D008214:Lymphocytes / Q000528:radiation effects*; D011829:Radiation Dosage; D011836:Radiation Tolerance; D013601:T-Lymphocytes / Q000276:immunology
D007073:Immunoglobulin E