Met, the HGF-SF receptor: another receptor for Listeria monocytogenes.
The bacterium Listeria monocytogenes invades a variety of cells in vitro and in vivo. Two proteins are crucial in this process: internalin, which interacts with E-cadherin, and InlB. The first identified ligand for InlB was gC1qR, which has no cytoplasmic domain. The newly discovered InlB receptor, Met, fits with the known InlB-induced signals.
Unité des Interactions Bactéries-cellules, Institut Pasteur, 28 rue du Dr Roux, 75015 Paris, France. pcossart@pasteur.fr
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D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism*; D006801:Humans; D008089:Listeria monocytogenes / Q000378:metabolism* / Q000472:pathogenicity*; D008088:Listeriosis / Q000382:microbiology*; D019859:Proto-Oncogene Proteins c-met / Q000378:metabolism*
D001426:Bacterial Proteins; C069761:internalin protein, Bacteria; D019859:Proto-Oncogene Proteins c-met