Postpneumonic empyema in childhood.
Fifty-six patients with postpneumonic empyema were treated by sulbactam/ampicillin or cephalothin and netilmicin. Dose of sulbactam/ampicillin was 200 mg/kg per day and of cephalothin was 200 mg/kg per day, and of netilmicin was 5 mg/kg per day. Sulbactam/ampicillin alone was used in 27 patients. Twenty-nine patients were treated with cephalothin plus netilmicin. Days on intravenous antibiotics, days with chest tube, decortication rate, and duration of hospitalization were significantly shorter in sulbactam/ampicillin treatment group compared to cephalothin plus netilmicin group. This study shows that sulbactam/ampicillin is a safe and effective agent in the treatment of postpneumonic empyema in childhood.
Department of Pediatrics, Ondokuz Mayis University Faculty of Medicine, Samsun, Turkey.
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N
Belet
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S
Uysal
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E
Bernay
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Gurses
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D016724:Empyema, Pleural / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007769:Lactams; D008297:Male; D009428:Netilmicin / Q000627:therapeutic use*; D018410:Pneumonia, Bacterial / Q000150:complications*; D018709:Statistics, Nonparametric
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D007769:Lactams; D009428:Netilmicin