Lower eyelid CO(2) laser rejuvenation: a randomized, prospective clinical study.
OBJECTIVE
The effect of transconjunctival blepharoplasty alone compared with transconjunctival blepharoplasty and CO(2) laser skin resurfacing on lower lid bulging and wrinkles was examined.


METHODS
Randomized clinical trial.


METHODS
Forty-four subjects, including 13 men and 31 women.


METHODS
Subjects were prospectively randomly assigned into two groups: (1) transconjunctival blepharoplasty with immediate CO(2) laser resurfacing or (2) transconjunctival blepharoplasty with CO(2) laser resurfacing 2 months later. Standardized photographs were taken before and 2 months after each procedure. A trained, masked observer graded the photographs.


METHODS
Bulging and wrinkles of the medial, central, and lateral portions of the lower lid were scored and compared at specified end points.


RESULTS
Transconjunctival blepharoplasty alone resulted in an improvement in lower lid bulging in 92% of subjects, whereas lower lid wrinkling worsened in 46%. When transconjunctival blepharoplasty was performed with simultaneous CO(2) laser resurfacing, or with CO(2) laser resurfacing 2 months later, a statistically significant improvement in wrinkles occurred (chi square = 20.625; P < 0.0005). The timing of the procedures had no statistically significant effect on final outcome. No subject had lower lid retraction develop.


CONCLUSIONS
Transconjunctival blepharoplasty and adjunctive CO(2) laser resurfacing represents an excellent alternative to transcutaneous lower blepharoplasty. The procedure addresses lower lid wrinkles, skin redundancy, and fat herniation without a scar and with little risk of lower lid retraction.
Department of Ophthalmology, University of California San Francisco, San Francisco, California, USA.
S R
SR
Carter
S R
SR
Seiff
P H
PH
Choo
P
P
Vallabhanath
D019882:Blepharoplasty; D005143:Eyelids / Q000601:surgery*; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D011446:Prospective Studies; D015361:Rhytidoplasty / Q000379:methods*; D015595:Skin Aging; D016896:Treatment Outcome