[Results of cytogenetic studies of the consequences of the Chernobyl accident].
The selected results of the cytogenetic studies of the Chernobyl accident consequences were summarised. The chromosomal aberrations were used as a method of biodosimetry for a dose assessment for victims during the initial period after the Chernobyl accident. A good correlation between doses calculated based on chromosomal aberrations (dicentrics) and severity of acute radiation syndrome observed in clinic was found. The biodosimetry based on conventional cytogenetic technique (dicentrics) has been unsuccessful for various groups (rehabilitation workers, evacuees, inhabitants of contaminated areas) sampled long time after the Chernobyl accident. The possible reasons of the failure are analysed. The original results of multiaberration cell yield observed in different cohorts of the Chernobyl victims are presented. The problems related to the phenomena are discussed.
Medical Radiological Research Centre Russian Academy of Medical Science, Obninsk, 249036 Russia. mrrc@obninsk.ru
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Sevan'kaev
D002869:Chromosome Aberrations; D006801:Humans; D011210:Power Plants; D011832:Radiation Injuries / Q000235:genetics*; D018788:Radioactive Hazard Release; D011874:Radiometry; D014455:Ukraine