Wegener's granulomatosis: diagnostic dilemma.
Wegener's granulomatosis is a systemic disease characterized by a granulomatous lesion that can affect any organ throughout the body. This case-report illustrates the problem posed by a patient presenting with bilateral serous otitis media with marked sensorineural hearing loss, facial nerve paralysis and an atypical serological picture. The importance of early diagnosis and the protocol for the management of a patient with an uncertain diagnosis is discussed. Due to atypical presentations, only a high index of suspicion will ensure an early diagnosis.
Department of Otolaryngology, North Riding Infirmary, Middlesbrough, UK. enter@onyxnet.co.uk
A
A
Banerjee
J M
JM
Armas
J H
JH
Dempster
D000208:Acute Disease; D000368:Aged; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005158:Facial Paralysis / Q000209:etiology; D014890:Granulomatosis with Polyangiitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006319:Hearing Loss, Sensorineural / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D010034:Otitis Media with Effusion / Q000209:etiology; D013256:Steroids / Q000627:therapeutic use
D019268:Antibodies, Antineutrophil Cytoplasmic; D007166:Immunosuppressive Agents; D013256:Steroids; D003520:Cyclophosphamide; D002097:C-Reactive Protein