Postvaccine vasculitis: a report of three cases.
BACKGROUND
Vaccines may be responsible for adverse effects, mainly local fugitive and benign reactions. However, few cases of systemic vasculitis have been described. We report three new cases, suggesting the responsibility of vaccination in starting or reactivating systemic vasculitis.


METHODS
We report two cases in a 64- and a 68-year-old woman with polymyalgia rheumatica and temporal arteritis after influenza and tetanus vaccination respectively, and one case in a 30-year-old man with periarteritis nodosa after hepatitis B vaccination.


CONCLUSIONS
Knowledge of such complications deserve to be expanded in order to: 1) avoid re-immunisations which are likely to result in more serious consequences; 2) avoid aggravation or reactivation of a vasculitis; and 3) control serology before hepatitis B vaccination in all persons at risk of HBV infection.
Service de médecine interne, hôpital de la Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris, France.
D
D
Saadoun
P
P
Cacoub
D
D
Mahoux
A
A
Sbai
J C
JC
Piette
D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D005260:Female; D013700:Giant Cell Arteritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D017325:Hepatitis B Vaccines / Q000009:adverse effects*; D006801:Humans; D007252:Influenza Vaccines / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010488:Polyarteritis Nodosa / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011111:Polymyalgia Rheumatica / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013256:Steroids; D013745:Tetanus Toxoid / Q000009:adverse effects*
D000893:Anti-Inflammatory Agents; D017325:Hepatitis B Vaccines; D007252:Influenza Vaccines; D013256:Steroids; D013745:Tetanus Toxoid