[Pulmonary lymphangioleiomyomatosis in a menopaused woman].
We report an unusual case of pulmonary lymphangioleiomyomatosis in a menopaused woman who had been taking estrogen hormone replacement therapy for several years. The characteristic feature of this uncommon disease is a proliferation of non-tumoral abnormal smooth muscle cells within the alveolar walls, and around the bronchi, lymph nodes and blood vessels. About twenty cases of pulmonary lymphangioleiomyomatosis have been described in menopaused women, who generally were taking estrogen hormone replacement therapy. This subpopulation does not appear to present any particular clinical, functional or radiographic features.
Zeggane
A
A
Service de Pneumologie, Hôpital de Longjumeau, 159 rue du Président F. Mitterrand, 91160 Longjumeau, France.
Assouline
P S
PS
Tebboune
D
D
Levasseur
P
P
Dulmet
E
E
Oliviero
G
G
D000726:Androgen Antagonists / Q000008:administration & dosage; D001706:Biopsy; D002916:Chylothorax / Q000209:etiology; D003534:Cyproterone / Q000008:administration & dosage; D004958:Estradiol / Q000008:administration & dosage; D015914:Estrogen Replacement Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D018192:Lymphangioleiomyomatosis / Q000000981:diagnostic imaging / Q000473:pathology; D008535:Megestrol; D008593:Menopause; D008875:Middle Aged; D009649:Norpregnadienes / Q000008:administration & dosage; D045167:Progesterone Congeners / Q000008:administration & dosage; D013902:Radiography, Thoracic; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D000726:Androgen Antagonists; D009649:Norpregnadienes; D045167:Progesterone Congeners; D004958:Estradiol; C038501:nomegestrol acetate; D003534:Cyproterone; D008535:Megestrol