Empirical treatment of sepsis in neutropenic patients.
Mortality associated with febrile neutropenia has dramatically decreased over the last three decades; a pivotal role has been played by the concept of hospital-based empirical therapy with broad-spectrum combinations of antibiotics. Nevertheless, there is evidence that a subgroup of patients with febrile neutropenia might benefit from less aggressive treatments.
Service de Médecine et Laboratoire d'Investigation Clinique, Institut Jules Bordet, Centre des Tumeurs de l'Université Libre de Bruxelles, rue Héger-Bordet 1, 1000 Bruxelles, Belgium.
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Klastersky
D000553:Ambulatory Care; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D009503:Neutropenia / Q000150:complications / Q000188:drug therapy*; D010343:Patient Admission; D018579:Patient Selection; D018805:Sepsis / Q000150:complications / Q000188:drug therapy*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents