Cutaneous plasmacytosis: an unusual presentation sharing features with POEMS syndrome?
Cutaneous plasmacytosis is a recently described skin disorder consisting of brown to red papules and nodules containing polyclonal plasmacytes. In this particular case, leg ulcers developed but also a diffuse patchy hyperpigmentation coexisting with a primary hypothyroidisim. The last two signs have only been described to date in POEMS syndrome, which is linked to monoclonal plasmacytic proliferation, and might suggest an overlap between these two entities.
Cerottini
J P
JP
Department of Dermatology (CHUV/DHURDV), Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. jpcerottini@hotmail.com
Guillod
J
J
Vion
B
B
Panizzon
R G
RG
D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D006801:Humans; D006942:Hypergammaglobulinemia / Q000473:pathology; D007871:Leg Ulcer / Q000473:pathology; D008297:Male; D016878:POEMS Syndrome / Q000473:pathology; D010950:Plasma Cells / Q000473:pathology*; D012871:Skin Diseases / Q000276:immunology / Q000473:pathology*