[Myelin basic protein. Structure, properties, function and role in diagnosing demyelinating diseases].
Physico-chemical properties and biological role of myelin basic protein (MBP)--one of the main myelin membrane proteins are reviewed. The data on MBP phosphorylation, methylation, fatty acid acylation and on interaction with lipid molecules in the human and animals bodies are presented. Much attention has been paid to the discussion of the diagnostic and clinical significance of the MBP, as the marker of demyelinating process in the central and peripheral nervous system.
Serbsky National Research Centre for Social & Forensic Psychiatry, 23 Kropotkinsky Per., Moscow, Russia.
V P
VP
Chekhonin
O I
OI
Gurina
T B
TB
Dmitrieva
A V
AV
Semenova
E A
EA
Savchenko
M E
ME
Grigor'ev
D003711:Demyelinating Diseases / Q000175:diagnosis*; D006801:Humans; D004676:Myelin Basic Protein / Q000737:chemistry / Q000502:physiology; D011487:Protein Conformation
D004676:Myelin Basic Protein