[Embryonic stem cells (from fundamental biology to medicine)].
The recent achievements in isolation, primary and long term culturing, cell Immunophenotyping, SAGE--mRNA--profiling, the clonogenic growth parameters of embryonic stem cells and mesenchymal stem cells have been outlined in connection with cell pluripotency and restricted differentiation, mediated by signals both in culture and in situ. Multidisciplinary data obtained by cell biologists, embryologists with recent functional genomic data give the new way for practical implementation of bioimplants derived from embryonic stem cell for cell-replacement therapy.
Moscow Institute of Fine Chemical Technology.
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D000818:Animals; D002454:Cell Differentiation; D002455:Cell Division; D002986:Clinical Trials as Topic; D004622:Embryo, Mammalian / Q000166:cytology*; D004627:Embryonic Induction; D016678:Genome; D006801:Humans; D008648:Mesoderm / Q000166:cytology; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology*; D014407:Tumor Cells, Cultured