Amelanotic corneal melanoma after a blast injury.
OBJECTIVE
To report a case of a corneal melanoma after trauma.


METHODS
Case report.


RESULTS
A 68-year-old man sustained an ocular injury from a blast furnace explosion in 1958. In 1998, he underwent a penetrating keratoplasty for a corneal scar. Histologic examination and cell markers of the host button revealed intrastromal and subepithelial melanoma. No clinical or microscopic evidence of adjacent conjunctival or uveal melanoma was found.


CONCLUSIONS
Melanoma of the cornea can present as a stromal opacity after trauma.
Department of Ophthalmology, University of California, San Francisco, CA, USA.
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Naseri
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Howes
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Paglen
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001753:Blast Injuries / Q000150:complications*; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D065306:Corneal Injuries; D005131:Eye Injuries / Q000150:complications*; D005134:Eye Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D015948:Keratoplasty, Penetrating; D008297:Male; D018328:Melanoma, Amelanotic / Q000209:etiology* / Q000473:pathology / Q000601:surgery
D014408:Biomarkers, Tumor