Generalized eczematous reaction to budesonide in a nasal spray with cross-reactivity to triamcinolone.
A 78-year-old woman suffered a generalized eczematous hypersensitivity reaction following the use of an intranasal budesonide inhaler. Patch testing demonstrated positive reactions to both budesonide and triamcinolone. Her eczema responded to emollients, betamethasone dipropionate ointment and cessation of her intranasal budesonide inhaler.
Skin and Cancer Foundation, Melbourne, Victoria, Australia. epoon@mail.com
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D000280:Administration, Inhalation; D000287:Administration, Topical; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D019819:Budesonide / Q000009:adverse effects*; D003429:Cross Reactions; D004485:Eczema / Q000139:chemically induced*; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000209:etiology*; D010328:Patch Tests; D012220:Rhinitis / Q000188:drug therapy; D014221:Triamcinolone / Q000009:adverse effects*
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D014221:Triamcinolone; D019819:Budesonide