2-Octyl cyanoacrylate medical adhesive in treatment of a corneal perforation.
OBJECTIVE
To describe a case of successful treatment of a corneal perforation with 2-octyl cyanoacrylate.


METHODS
2-Octyl cyanoacrylate was applied at the slit lamp with topical proparacaine anesthesia to a cornea with an inferior perforation with iris plugging the defect.


RESULTS
After application of 2-octyl cyanoacrylate, the anterior chamber was noted to deepen, and visual acuity improved to 20/200. The glue remained intact for more than 6 weeks and eventually fell out. The underlying cornea healed without scarring, vascularization, or thinning.


CONCLUSIONS
We have described a case in which 2-octyl cyanoacrylate was used to treat a corneal perforation with excellent results. Further study of this adhesive will be useful in comparing the effectiveness and safety of 2-octyl cyanoacrylate with that of previously studied adhesives.
Department of Ophthalmology, University of Colorado, Denver, USA.
M J
MJ
Taravella
C D
CD
Chang
D000867:Anterior Chamber / Q000473:pathology; D003315:Cornea / Q000187:drug effects* / Q000473:pathology; D003316:Corneal Diseases / Q000188:drug therapy* / Q000473:pathology; D003487:Cyanoacrylates / Q000627:therapeutic use*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D012422:Rupture, Spontaneous; D012449:Safety; D014014:Tissue Adhesives / Q000627:therapeutic use*
D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate