Miniaturized total analysis systems for biological analysis.
This review article discusses and documents the basic philosophies, concepts and current advances in the field of micro-TAS development, with special emphasis on applications in the arena of biosciences. After a brief overview of miniaturization theory and fabrication techniques, areas of microfluidic component development, detection protocols, biochemical assays, and integrated biological analyses are addressed.
Zeneca SmithKline Beecham Centre for Analytical Sciences, Imperial College, London, UK.
S C
SC
Jakeway
A J
AJ
de Mello
E L
EL
Russell
D001669:Biochemical Phenomena; D002845:Chromatography / Q000379:methods; D019075:Electrophoresis, Capillary / Q000379:methods; D006801:Humans; D008832:Microchemistry / Q000295:instrumentation* / Q000379:methods*; D008904:Miniaturization; D016133:Polymerase Chain Reaction / Q000379:methods