Yield of vancomycin-resistant enterococci and multidrug-resistant Enterobacteriaceae from stools submitted for Clostridium difficile testing compared to results from a focused surveillance program.
It has been suggested that a method of performing surveillance for vancomycin-resistant enterococci (VRE) is to screen specimens submitted for Clostridium difficile testing. We compared this approach to our focused surveillance program of high-risk units during October 1997 to compare the yield of VRE and multidrug-resistant Enterobacteriaceae (MDRE) with both methods. Of the stools submitted for C. difficile testing, 14% were positive for VRE or MDRE, whereas rectal swabs from routine surveillance yielded 11% VRE- or MDRE-positive results. Although stools submitted for C. difficile testing resulted in a higher percentage of positive cultures, 14 VRE- and 2 MDRE-positive patients from our high-risk population were missed because many patients had no stool submitted for C. difficile testing. Therefore, while screening stools submitted for C. difficile testing cannot replace our focused surveillance program, it appears advantageous to assess these stools at various intervals to detect new patient reservoirs of drug-resistant organisms that may benefit from routine surveillance cultures.
Department of Pathology, Clinical Microbiology Division, Northwestern Memorial Hospital and Northwestern University Medical School, Chicago, Illinois 60611, USA. dhacek@nmh.org
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Hacek
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Noskin
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Peterson
D016360:Clostridioides difficile / Q000302:isolation & purification*; D003470:Culture Media; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D004755:Enterobacteriaceae / Q000187:drug effects / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000382:microbiology; D016983:Enterococcus / Q000187:drug effects / Q000302:isolation & purification*; D004761:Enterocolitis, Pseudomembranous / Q000382:microbiology*; D005243:Feces / Q000382:microbiology*; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis / Q000382:microbiology; D006801:Humans; D011159:Population Surveillance; D013048:Specimen Handling; D020713:Vancomycin Resistance
D003470:Culture Media