Thalamic hand dystonia: an MRI anatomoclinical study.
Focal dystonia has been attributed to lesions involving the basal ganglia and/or thalamus. Hand dystonia was studied in a patient with a unilateral thalamic infarction documented by MRI. A 18-year-old girl presented with severe isolated dystonia of the right hand as a sequel of perinatal infarction. MRI scan revealed infarction affecting part of the dorsomedian, lateral posterior, ventral lateral, ventral posterior lateral nuclei, and centromedian-parafascicular nucleus of the contralateral thalamus. The unique MRI anatomoclinical presentation of this case, taken together with the literature data, could provide evidence that a lesion affecting one or several thalamic nuclei, including the centromedian nucleus, can induce hand dystonia.
Department of Clinical Pharmacology Medecine (Neurology), College of Medicine, P.O. Box 35, Sultan Qaboos University, Al-Khod, Muscat-123, Sultanate of Oman.
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Deleu
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Lagopoulos
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Louon
D000293:Adolescent; D002544:Cerebral Infarction / Q000150:complications* / Q000175:diagnosis; D003131:Combined Modality Therapy; D004292:Dominance, Cerebral; D020821:Dystonic Disorders / Q000188:drug therapy / Q000209:etiology* / Q000628:therapy; D005260:Female; D006227:Hand Deformities, Acquired / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D013788:Thalamus / Q000098:blood supply* / Q000503:physiopathology; D004561:Transcutaneous Electric Nerve Stimulation