Relationships between tissue concentrations of polycyclic aromatic hydrocarbons and antioxidative responses of marine mussels, Perna viridis.
Local mussels, Perna viridis, were transplanted from a relatively clean site to various polluted sites in Hong Kong. After a 30-day field exposure, different antioxidant parameters including glutathione S transferase (GST), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), NADPH DT-diaphorase (DT-d), glutathione (GSH) and lipid peroxidation were quantified, and tissue concentrations of benzo[a]pyrene (B[a]P) as well as a total of five polycyclic aromatic hydrocarbons (PAHs) with potential carcinogenicity were determined for individual mussels. Results indicated that: (1) tissue concentrations of B[a]P and total PAHs from the same site were highly variable; (2) gill SOD, DT-d and lipid peroxidation showed no response to tissue pollutants; (3) the majority of the antioxidant parameters were induced by increasing tissue pollutant concentrations; and (4) amongst the various parameters, oxyradical scavenger GSH best correlated with tissue concentrations of pollutants.
Cheung
C C
CC
Department of Biology and Chemistry, Centre for Coastal Pollution and Conservation, City University of Hong Kong, Tat Chee Avenue, Kowloon, SAR, Hong Kong, Hong Kong.
Zheng
G J
GJ
Li
A M
AM
Richardson
B J
BJ
Lam
P K
PK
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D049872:Bivalvia / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D005980:Glutathione Reductase / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D006723:Hong Kong; D015227:Lipid Peroxidation; D009252:NADPH Dehydrogenase / Q000378:metabolism; D011084:Polycyclic Aromatic Hydrocarbons / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism; D014877:Water Pollution, Chemical / Q000009:adverse effects*
D000975:Antioxidants; D011084:Polycyclic Aromatic Hydrocarbons; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D009252:NADPH Dehydrogenase; D005980:Glutathione Reductase; D005982:Glutathione Transferase