Characterization of contraction and perfusion in the lateral border zone between normal and ischemic myocardium following coronary occlusion by myocardial contrast echocardiography.
We performed myocardial contrast echocardography with power Doppler imaging during left anterior descending occlusion in 10 dogs, and found that video intensity and dyssynergy in lateral border zones of ischemic myocardium were present, but the video intensity was significantly lower than adjacent nonischemic zones. The results of this study demonstrate that levels of perfusion and contraction, which are intermediate between normal and central ischemic zones, are observed in the border zone with coronary occlusion by myocardial contrast echocardography, and may have implications in identifying myocardium that will be spared necrosis and in measuring ultimate infarct size.
Cardiovascular Division, University of California at San Diego, USA.
H
H
Masugata
B
B
Peters
B
B
Cotter
K
K
Mizushige
A N
AN
DeMaria
D000418:Albumins; D000818:Animals; D003287:Contrast Media; D003326:Coronary Circulation / Q000502:physiology*; D004285:Dogs; D004452:Echocardiography; D018618:Echocardiography, Doppler, Color; D005466:Fluorocarbons; D007091:Image Processing, Computer-Assisted; D009200:Myocardial Contraction / Q000502:physiology*; D009203:Myocardial Infarction / Q000000981:diagnostic imaging*; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging*
D000418:Albumins; D003287:Contrast Media; C099458:FS 069; D005466:Fluorocarbons