[Effects of biologically-active dietary supplement from marine biology on cholinesterase activity and blood lipid peroxidation in humans].
Influence of dietary supplement Tinrostim-C on cholinesterase (ChE) activity and serum lipids peroxidation (LP) in patients whose work connects with emotional stress was examined. Activity of ChE was measured by Ellman calorimetric method (with acetylthiocholin as substrate), LP--by fluorimetric method with malone dialdehyde. Tinrostim-C was given three times a day in 0.5 g. On the 10th day of taking the preparation an activity of serum ChE increased 23.5% higher and had been staying higher during the whole period of observation. In vitro experiments showed an activating effect of Tinrostim-C and piracetam for serum ChE. The level of LP being initially higher was decreasing to values close to normal and had been staying at decreased level during the whole period of observation.
Romanenko
V A
VA
Kovalev
N N
NN
Enikeeva
N A
NA
Epshteĭn
L M
LM
D000328:Adult; D000818:Animals; D001205:Ascorbic Acid / Q000008:administration & dosage; D002151:Calorimetry; D002802:Cholinesterases / Q000097:blood*; D049832:Decapodiformes; D019587:Dietary Supplements; D005470:Fluorometry; D006801:Humans; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D012758:Shellfish; D013315:Stress, Psychological / Q000097:blood / Q000178:diet therapy; D013997:Time Factors
D008315:Malondialdehyde; D002802:Cholinesterases; D001205:Ascorbic Acid