Familial and sporadic primary pulmonary hypertension is caused by BMPR2 gene mutations resulting in haploinsufficiency of the bone morphogenetic protein tùype II receptor.
Thomson
J
J
1University of Leicester, Leicester, United Kingdom; 2Children's Hospital Medical Center, Cincinnati, OH, USA; 3Royal Brompton and Harefield Hospitals, Harefield, United Kingdom; 4Royal Freeman Hospital, Newcastle, United Kingdom; 5Papworth Hospital, Cambridge, United Kingdom; 6Vanderbilt University Medical Center, Nashville, TN, USA
Machado
R
R
Pauciulo
M
M
Morgan
N
N
Yacoub
M
M
Corris
P
P
McNeil
K
K
Loyd
J
J
Nichols
W
W
Trembath
R
R