Simultaneous isolation of verotoxin-producing strains of Escherichia coli O128:H2 and viruses in gastroenteritis outbreaks.
Three outbreaks of gastroenteritis from which the Verotoxin producing Escherichia coli serotype O128:H2 was isolated are reported. In addition Norwalk-like viruses were detected in patients from two of the outbreaks and astrovirus in the third outbreak. While it cannot be specifically determined which of these agents played the major role in these outbreaks, the findings suggest that the viral agents need to be considered in investigations of gastroenteritis outbreaks, regardless of whether bacterial enteropathogens have also been isolated. This study points to a strong need to investigate gastroenteritis outbreaks for both bacterial and viral agents and to review in detail the asymptomatic carriage rate of Verotoxin-producing bacteria and gastroenteritis-associated viral agents; these areas of public health significance have been largely neglected.
Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia.
K A
KA
Bettelheim
V
V
Bennett-Wood
D
D
Lightfoot
P J
PJ
Wright
J A
JA
Marshall
D001315:Australia / Q000453:epidemiology; D017250:Caliciviridae Infections / Q000453:epidemiology / Q000821:virology; D004196:Disease Outbreaks; D004926:Escherichia coli / Q000302:isolation & purification* / Q000378:metabolism / Q000472:pathogenicity; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology; D005759:Gastroenteritis / Q000453:epidemiology* / Q000382:microbiology / Q000821:virology; D006801:Humans; D009663:Norwalk virus / Q000302:isolation & purification; D012189:Retrospective Studies; D012703:Serotyping; D022603:Shiga Toxins / Q000096:biosynthesis* / Q000302:isolation & purification; D014774:Virulence
D022603:Shiga Toxins