Postprandial lipid handling.
The etiological importance of postprandial lipid metabolism in the development of coronary artery disease is now well established. Since then, the work of Patsch and others has helped to establish the etiological importance of postprandial lipid metabolism in the development of coronary artery disease. Dietary and pharmacological interventions have been shown to produce dramatic improvement in postprandial lipid handling in high risk groups and have potential to prevent coronary artery disease through these effects. Research effort continues to focus on the complex mechanisms which underlie defects in postprandial lipid handling, with a view to understanding how lifestyle variables such as diet can be modified to prevent coronary artery disease.
Griffin
B A
BA
Centre for Nutrition and Food Safety, School of Biomedical and Life Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, UK.
Fielding
B A
BA
D001057:Apolipoproteins E / Q000235:genetics; D015243:Cholesterol, VLDL / Q000502:physiology; D002914:Chylomicrons / Q000096:biosynthesis / Q000378:metabolism; D003327:Coronary Disease / Q000209:etiology / Q000517:prevention & control*; D004032:Diet; D004041:Dietary Fats / Q000493:pharmacokinetics / Q000494:pharmacology; D004730:Endothelium, Vascular / Q000502:physiology; D006801:Humans; D000960:Hypolipidemic Agents / Q000494:pharmacology; D007408:Intestinal Absorption / Q000502:physiology; D008019:Life Style; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood; D019518:Postprandial Period
D001057:Apolipoproteins E; D015243:Cholesterol, VLDL; D002914:Chylomicrons; D004041:Dietary Fats; D000960:Hypolipidemic Agents; D008055:Lipids