Comparative study of alkaline phosphatase and prostate specific antigen in prostate cancer.
The study comprised between healthy and benign controls and proven 62 cases of prostate cancer at different clinical stages. The mean value of increasing level of PSA in group III was found to be highly significant when compared with group I. Whereas, the mean value of elevated levels of ALP in stage III and IV from group III was found to be highly significant when compared with group I. Though the mean value of ALP was increased in stage I and II from group III when compared with group I, it was not found highly significant. Hence the elevated levels of ALP were significantly correlated with advanced stages of prostate cancer. Whereas, increased levels of PSA contribute to the diagnosis of potentially increased volume of the prostate cancer.
Gadre
S G
SG
Dept of Biochemistry, Institute of Science, 15, MC Road, Mumbai-32.
Kale
K U
KU
Hedge
R
R
Raste
A S
AS
D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D002277:Carcinoma / Q000175:diagnosis* / Q000201:enzymology / Q000276:immunology; D016022:Case-Control Studies; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000201:enzymology / Q000276:immunology
D014408:Biomarkers, Tumor; D000469:Alkaline Phosphatase; D017430:Prostate-Specific Antigen