Ocular deposition of copper associated with multiple myeloma.
OBJECTIVE
To report a case of hypercupremia with deposits in both eyes on the Descemet's membrane, surface of the iris, and lens capsule associated with multiple myeloma.


METHODS
Case report.


RESULTS
A 64-year-old white woman had metallic deposits in both eyes on the central Descemet's membrane, surface of the iris, and the anterior and posterior lens capsule. A systemic examination revealed an elevated serum copper, normal serum ceruloplasmin, and an increased level of total protein and IgG kappa gammaglobulin. Based on these results, she was diagnosed with multiple myeloma.


CONCLUSIONS
Copper deposits on the Descemet's membrane, surface of the iris, and lens capsule may be the first sign of multiple myeloma.
Department of Ophthalmology, Rush Medical College of Rush University, 1653 West Congress Parkway, Chicago, IL 60612, USA.
A S
AS
Hawkins
R M
RM
Stein
B I
BI
Gaines
T A
TA
Deutsch
D002570:Ceruloplasmin / Q000032:analysis; D003300:Copper / Q000378:metabolism*; D003886:Descemet Membrane / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D007498:Iris / Q000378:metabolism* / Q000473:pathology; D007903:Lens Capsule, Crystalline / Q000378:metabolism* / Q000473:pathology; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis / Q000378:metabolism*
D003300:Copper; D002570:Ceruloplasmin