Hypopigmented mycosis fungoides: a report of 7 cases and review of the literature.
Over the last 2 decades, hypopigmented macules have been reported with increasing frequency as an initial presentation of mycosis fungoides (MF). We retrospectively reviewed 7 patients with hypopigmented MF. The mean age was 35 years at disease onset, with a mean of 5.5 years' duration of illness before presentation. All of our patients were Fitzpatrick skin type IV or V, and most reported pruritus. Histologic findings in all cases were consistent with MF. Treatment with topical nitrogen mustard produced repigmentation in 4 of 6 patients.
University of Missouri, Kansas City School of Medicine, USA.
M L
ML
Stone
A R
AR
Styles
C J
CJ
Cockerell
A G
AG
Pandya
D000328:Adult; D001741:Black or African American; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D005260:Female; D006801:Humans; D017496:Hypopigmentation / Q000209:etiology; D008297:Male; D008466:Mechlorethamine / Q000627:therapeutic use; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology*
D018906:Antineoplastic Agents, Alkylating; D008466:Mechlorethamine