Presentation of cutaneous mastocytosis in 173 children.
This is a retrospective review of the case files and clinical photographs of 173 children diagnosed with cutaneous mastocytosis by a dermatologist in an exclusively paediatric practice. Of the 98 males and 75 females, 51% had mastocytomas, 47% had urticaria pigmentosa and three patients had diffuse cutaneous mastocytosis. Of these cases, 87% first appeared prior to or at 6 months of age. Flushing occurred in 26% of urticaria pigmentosa cases, 29% of mastocytomas and 100% of diffuse cutaneous mastocytosis. Blistering was noted in 23% of urticaria pigmentosa, 31% of mastocytomas and 100% of diffuse cases. Neither symptom was noted in 59% of urticaria pigmentosa and 49% of mastocytomas. There were three cases with a positive family history. The finding of a palmar mastocytoma has only once been previously reported. Illustrated descriptions of our cases are provided.
New Children's Hospital, Sydney, New South Wales, Australia. dreg1@canc.rpa.cs.nsw.gov.au
R
R
Hannaford
M
M
Rogers
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008415:Mastocytosis / Q000175:diagnosis* / Q000473:pathology; D008499:Medical Records; D012189:Retrospective Studies; D014582:Urticaria Pigmentosa / Q000175:diagnosis