[Features of overall and local immunity in patients which chronic rhinitis of different etiology].
The systemic and mucosal immune status in 50 patients with all-year-round allergic rhinitis (AYRAR), chronic infectious rhinitis (CIR) and non-atopic eosinophilic rhinitis (NER) was evaluated. Patients with concomitant pathology (bronchicial asthma, chronic bronchitis, sinusitis, etc.) were found to have changes in the systemic immunity. Patients with AYRAR and CIR had a high level of SIgA in their nasal secretions, and in the latter--also an elevated level of local IgG NER patients exhibited a considerable decrease in local production of immunoglobulins. In the nasal secretions of AYRAR and CIR patients high phagocytic activity of neutrophilis was established in the nitro blue tetrazolum test. The results of the study showed the expediency of determination of immune disturbances in these patients with a view to administration of immunocorrective therapy.
Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia.
E P
EP
Foshina
L I
LI
Krasnoproshina
O V
OV
Slatinova
S A
SA
Skhodova
D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D006801:Humans; D007111:Immunity, Cellular; D018928:Immunity, Mucosal; D007136:Immunoglobulins / Q000097:blood; D008875:Middle Aged; D012220:Rhinitis / Q000097:blood / Q000209:etiology / Q000276:immunology*
D007136:Immunoglobulins