Anterior cervical instrumentation enhances fusion rates in multilevel reconstruction in smokers.
This retrospective consecutive case study evaluated the effect of anterior plating on multilevel anterior cervical decompressions and fusions in smokers and non-smokers. Multilevel anterior cervical decompression and fusion surgery in smokers provides an important challenge. Higher nonfusion rates in smokers have been reported. Cigarette smoking has been shown to interfere with bone metabolism and revascularization and to suppress bone formation. One hundred six patients underwent anterior cervical decompression and fusion using autografts or allografts and anterior plating. The minimum follow-up was 12 months. The mean age was 50.12 years (+/- 11.72; range, 27 to 80 years). Autografts were used in 90 patients and allograft in 16. The mean level fused was 2.74 (+/- 0.61). Forty-six (45.5%) patients were smokers. Successful fusion was achieved in all but three patients (97.17%). C5 root weakness was seen in four patients (3.8%); two patients experienced acute airway obstruction, of which one required tracheotomy. Temporary recurrent laryngeal nerve palsy developed in three (2.8%) patients. A fusion rate of 97% was achieved in multilevel anterior cervical decompression and fusions using anterior plating. No difference in fusion rates between smokers and nonsmokers was seen. Anterior cervical plating markedly improved the fusion rate in smokers.
Department of Neurosurgery, Christiana Care Health System, Newark, Delaware, USA.
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001860:Bone Plates; D002574:Cervical Vertebrae / Q000378:metabolism / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016348:Osseointegration; D011859:Radiography; D012907:Smoking / Q000009:adverse effects*; D013122:Spinal Diseases / Q000000981:diagnostic imaging / Q000378:metabolism / Q000601:surgery*; D013123:Spinal Fusion / Q000295:instrumentation* / Q000379:methods