[Progress in optical imaging].
Different optical imaging technologies have significantly progressed over the last years. Besides advances in imaging techniques and image reconstruction, new "smart" optical contrast agents have been developed which can be used to detect molecular targets (such as endogenous enzymes) in vivo. The combination of novel imaging technologies coupled with smart agents bears great diagnostic potential both clinically and experimentally. This overview outlines the basic principles of optical imaging and summarizes the current state of the art.
Bremer
C
C
Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, USA.
Ntziachristos
V
V
Mahmood
U
U
Tung
C H
CH
Weissleder
R
R
D000818:Animals; D003287:Contrast Media; D005456:Fluorescent Dyes; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D055095:Optics and Photonics; D019265:Spectroscopy, Near-Infrared / Q000379:methods; D014054:Tomography / Q000379:methods*; D014172:Transillumination / Q000379:methods
D003287:Contrast Media; D005456:Fluorescent Dyes