Spontaneous DNA damage, genome instability, and cancer--when DNA replication escapes control.
Institute of Medical Radiobiology, University of Zürich and Paul Scherrer Institute, CH-8008, Zürich, Switzerland. schaer@imr.unizh.ch
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D000818:Animals; D002869:Chromosome Aberrations; D004249:DNA Damage; D004260:DNA Repair; D004261:DNA Replication; D020022:Genetic Predisposition to Disease; D006801:Humans; D051379:Mice; D008954:Models, Biological; D009154:Mutation; D009369:Neoplasms / Q000209:etiology* / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics; D015398:Signal Transduction