[Arguments in favor of adipocyte grafts with the S.R. Coleman technique].
The main criticism against fat reinjection procedures is related to whether it is possible to graft adipocytes or not. The ideal solution would be to perform biopsies a few months after the operation to check the evolution of the grafted tissue, but such an approach would be difficult to accept for our patients. To overcome this difficulty the authors have compiled all the arguments that plead in favor of adipocyte grafts when Coleman's technique is used. Peer demonstrated in animal studies that it is possible to graft fatty tissue and that more resorption occurs when the fragments are large in size. The histologic studies have shown that the different stages of Coleman's technique do not alter the viability of the adipocytes. A disorganization of the architecture of the lobules is observed, but this does not compromise the theory of adipocyte grafting. An MRI study, performed on ten patients, demonstrated that the reinjected fat cells persist several months after the procedure. These fat cells presented the same characteristics as the patient's native fat in the surrounding area. This impression was confirmed by histological analysis of the reinjected fatty tissue 18 months after the graft. Finally, the clinical results obtained on over 200 patients treated for various indications in plastic and cosmetic surgery lead us to believe that it is possible to perform grafts of fatty tissue.
Service de chirurgie plastique réparatrice et esthétique, hôpital la Conception, 147, boulevard Baille, 13005 Marseille, France. jlejauffret@free.fr
J L
JL
Jauffret
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P
Champsaur
A
A
Robaglia-Schlupp
L
L
Andrac-Meyer
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G
Magalon
D017667:Adipocytes / Q000502:physiology / Q000637:transplantation*; D001706:Biopsy; D002498:Centrifugation; D006084:Graft Rejection / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D015361:Rhytidoplasty / Q000379:methods; D014180:Transplantation / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D016896:Treatment Outcome