Laparoscopic abdominal staging in locally advanced cervical cancer.
In order to determine patterns of peritoneal spread in locally advanced cervical cancer, 59 patients with previously untreated stages IB and IIA tumor size > 4 cm, IIB, III and IVA cervical cancer were considered for laparoscopic abdominal staging. Fifty-six patients (95%) were considered suitable and underwent laparoscopy. Peritoneal spread was found in 15 (27%) patients. The location was pelvic in nine (17%), extra-pelvic in one (2%), both pelvic and extra-pelvic in four (8%). Peritoneal washing was positive in five (9%) patients, being the unique site of peritoneal spread in one. Overall, 16 (29%) patients had evidence of abdominal disease. The median number of positive sites was one (range 1-4); uterine serosa was positive in nine (17%) patients, pre-vesical peritoneum in seven (13%), Douglas peritoneum in five (10%), paracolic gutter in three (6%), adnexa and omentum in two (4%), and sigmoid serosa in one (2%) patient. One operative complication occurred and all patients were discharged the day after the procedure. To date, with a median follow-up of 27 months (range 7-38), no metastasis has been detected at the trocar insertion sites. To summarize, laparoscopic staging in locally advanced cervical cancer is a safe, feasible and simple technique which is able to accurately detect abdominal disease.
Departments of Gynecology and Obstetrics, Libero Istituto Universitario-Campus Biomedico, Rome; Departments of Gynecology and Obstetrics, Catholic University of The Sacred Heart, Rome; Departments of Gynecology and Obstetrics, University of Varese, Varese, Italy.
P.
P
Benedetti-Panici
F.
F
Maneschi
G.
G
Cutillo
M.
M
Congiu
M.
M
Franchi
M.
M
Amoroso
S.
S
Greggi
S.
S
Mancuso