Signaling via the IL-2 and IL-7 receptors from the membrane to the nucleus.
Laboratory of Molecular Immunology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1674, USA.
W J
WJ
Leonard
K
K
Imada
H
H
Nakajima
A
A
Puel
E
E
Soldaini
S
S
John
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D002455:Cell Division; D002462:Cell Membrane / Q000276:immunology / Q000378:metabolism; D002467:Cell Nucleus / Q000276:immunology / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism; D019281:Dimerization; D005786:Gene Expression Regulation; D006801:Humans; D053616:Janus Kinase 3; D007694:Killer Cells, Natural / Q000276:immunology; D051379:Mice; D018345:Mice, Knockout; D008894:Milk Proteins; D008958:Models, Molecular; D009154:Mutation; D010641:Phenotype; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D018121:Receptors, Cytokine / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D015375:Receptors, Interleukin-2 / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D020395:Receptors, Interleukin-7 / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D050799:STAT5 Transcription Factor; D016511:Severe Combined Immunodeficiency / Q000235:genetics / Q000276:immunology; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000276:immunology; D015534:Trans-Activators / Q000378:metabolism; D014960:X Chromosome / Q000235:genetics
D004268:DNA-Binding Proteins; D008894:Milk Proteins; D018121:Receptors, Cytokine; D015375:Receptors, Interleukin-2; D020395:Receptors, Interleukin-7; D050799:STAT5 Transcription Factor; D015534:Trans-Activators; D011505:Protein-Tyrosine Kinases; C507933:JAK3 protein, human; C507935:Jak3 protein, mouse; D053616:Janus Kinase 3