Biochemical profile of erythrocyte membrane of jaundiced neonates.
Studies in newborn humans have demonstrated alteration in the lipid, phospholipid and cholesterol content when compared with age-matched control. Membrane bound (Na+ + K+)ATPase activity is found to be significantly increased in jaundiced neonates. Alteration in membrane permeability characteristics in jaundiced neonates causes severe microenvironmental changes in red blood cell profile.
Mazumder
S
S
Department of Biochemistry, Institute of Child Health, Calcutta, India.
Sarkar
U
U
Sengupta
D
D
D001724:Birth Weight; D002463:Cell Membrane Permeability; D002784:Cholesterol / Q000097:blood; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004910:Erythrocyte Membrane / Q000737:chemistry* / Q000201:enzymology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007567:Jaundice, Neonatal / Q000097:blood*; D008297:Male; D008563:Membrane Lipids / Q000097:blood; D008565:Membrane Proteins / Q000097:blood; D010042:Ouabain / Q000494:pharmacology; D010743:Phospholipids / Q000097:blood; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors / Q000097:blood
D004791:Enzyme Inhibitors; D008563:Membrane Lipids; D008565:Membrane Proteins; D010743:Phospholipids; D010042:Ouabain; D002784:Cholesterol; D000254:Sodium-Potassium-Exchanging ATPase