Determination of the efficacy of preservation of non-eye area water-miscible cosmetic and toiletry formulations: collaborative study.
A collaborative study was conducted to test a method developed to distinguish between adequately and inadequately preserved cosmetic formulations. Nineteen laboratories participated in the study. Samples tested included shampoos, hair conditioners, oil-in-water emulsions, and water-in-oil-emulsions. Triplicate samples of 4 adequately preserved and 4 inadequately preserved cosmetic products were tested by each collaborative laboratory. Results showed that all inadequately preserved shampoo and conditioner samples failed to meet the acceptance criteria for adequately preserved formulations. Of the 51 preserved samples, 49 shampoos and 48 conditioners met the criteria for adequate preservation. All samples of inadequately preserved water-in-oil emulsions and oil-in-water emulsions failed to meet the acceptance criteria, whereas all adequately preserved emulsion formulations met the acceptance criteria.
Machtiger
N A
NA
Creanova, Inc, Piscataway, NJ 08855-0365, USA.
Fischler
G E
GE
Adams
M C
MC
Spielmaker
R
R
Graf
J F
JF
D000465:Algorithms; D003358:Cosmetics / Q000032:analysis*; D004655:Emulsions; D004783:Environmental Microbiology; D007202:Indicators and Reagents; D019064:Product Packaging; D011786:Quality Control; D015203:Reproducibility of Results; D012915:Soaps / Q000032:analysis
D003358:Cosmetics; D004655:Emulsions; D007202:Indicators and Reagents; D012915:Soaps