Refractory no-reflow successfully treated with local infusion of high-dose adenosine and verapamil--a case report.
No-reflow is an unpredictable complication following percutaneous coronary intervention. No-reflow is associated with myocardial ischemia and infarction and increased mortality. A case of refractory no-reflow is described that was rapidly and successfully treated with multiple infusions of high doses of verapamil and adenosine applied directly at the site of no-reflow through a perfusion catheter.
Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis 46202, USA.
W C
WC
Dillon
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Hadian
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ME
Ritchie
D000241:Adenosine / Q000008:administration & dosage* / Q000627:therapeutic use; D015906:Angioplasty, Balloon, Coronary; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D003326:Coronary Circulation; D003327:Coronary Disease / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D014665:Vasodilator Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D014700:Verapamil / Q000008:administration & dosage* / Q000627:therapeutic use
D014665:Vasodilator Agents; D014700:Verapamil; D000241:Adenosine