Evaluation of the viability of bone fragments.
We used laser Doppler flowmetry (LDF) to measure flux in cortical bone fragments as a method of determining their vascular status and viability. In an experimental tibial osteotomy measurements of flux were made from specific cortical sites both before and after osteotomy. Flux levels fell rapidly in non-vascularised fragments and remained significantly reduced throughout the experiment. By contrast, those in vascularised fragments were significantly reduced one and two hours after the osteotomy but then increased. From three hours after the osteotomy there was no significant difference in flux levels between the vascularised fragments and proximal bone stock. We conclude that measurement of bone flux by LDF may have a role in the objective evaluation of the viability of bone fragments, but that further studies are required to validate the technique before its adoption in the management of the injured patient.
CBD Porton Down, Salisbury, England, UK.
C M
CM
Hobbs
P E
PE
Watkins
D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D016025:Bone Transplantation; D005260:Female; D017078:Laser-Doppler Flowmetry; D010027:Osteotomy; D012756:Sheep; D013977:Tibia / Q000098:blood supply; D014022:Tissue Survival / Q000502:physiology*