Design based stereological methods for estimating the total number of objects in histological material.
The principle that formed the basis of the most popular "assumption based" stereological methods for counting cells that were available prior to the advent of the more recently developed "design based" methods will be described in general terms. The major weaknesses inherent in the older methods will be described, along with how they have been eliminated by the design based methods.
West
M J
MJ
Department of Neurobiology, Institute of Anatomy, University of Aarhus, 8000 Aarhus C, Denmark. mjw@ana.au.dk
D000818:Animals; D015982:Bias; D019295:Computational Biology / Q000379:methods*; D006652:Histological Techniques / Q000379:methods*; D006801:Humans