CTLA-4--the costimulatory molecule that doesn't: regulation of T-cell responses by inhibition.
Chambers
C A
CA
Howard Hughes Research Institute, Division of Immunology, Department of Molecular and Cellular Biology, University of California, Berkeley, California 94720, USA.
Allison
J P
JP
D000069594:Abatacept; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000235:genetics / Q000378:metabolism*; D018106:CD28 Antigens / Q000378:metabolism; D060908:CTLA-4 Antigen; D006706:Homeostasis; D006801:Humans; D018796:Immunoconjugates; D008213:Lymphocyte Activation; D051379:Mice; D018345:Mice, Knockout; D008954:Models, Biological; D011948:Receptors, Antigen, T-Cell / Q000235:genetics / Q000378:metabolism; D017634:Self Tolerance; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000276:immunology* / Q000378:metabolism*
D015703:Antigens, CD; D000943:Antigens, Differentiation; D018106:CD28 Antigens; D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; C556707:Ctla4 protein, mouse; D018796:Immunoconjugates; D011948:Receptors, Antigen, T-Cell; D000069594:Abatacept