Multiple aseptic pulmonary nodules with central necrosis in association with pyoderma gangrenosum.
Pulmonary manifestations of pyoderma gangrenosum are relatively rare. We report the case of a 45-year-old patient with multiple pulmonary nodules with central necrosis as assessed by CT scan. The patient had a 4-year history of pyoderma gangrenosum with only minor skin manifestations. A CT-guided, fine-needle biopsy of the lung revealed a nonspecific, inflammatory, aseptic necrotic process, which was comparable to the skin biopsy of one pyoderma lesion. Following the initiation of oral prednisolone therapy, a rapid resolution of the pulmonary nodules occurred. We conclude that pulmonary nodules represent a rare pulmonary manifestation of pyoderma gangrenosum.
Medical Clinic I, University Hospital, University of Technology, Aachen, Germany.
S
S
Krüger
W
W
Piroth
B
B
Amo Takyi
C
C
Breuer
E R
ER
Schwarz
D005260:Female; D006801:Humans; D008875:Middle Aged; D009336:Necrosis; D017511:Pyoderma Gangrenosum / Q000150:complications*; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D014057:Tomography, X-Ray Computed