Osteoclastic giant cell tumor of the pancreas: case report and literature review.
An unusual case of a 40-year-old woman seeking treatment for a 10-cm cystic neoplasm of the pancreas is described. Imaging revealed a large proteinaceous, fluid-filled cyst with a mural nodule. Laparotomy was successful with en bloc resection. Pathologic examination revealed a neoplastic mucinous epithelial tumor with an abundance of multinucleated tumor giant cells. This presentation is consistent with literature reports of an osteoclastic-type giant-cell tumor of the pancreas. The natural history, pathologic evaluation, and clinical implications of this rare neoplasm are discussed with reference to published reports.
Division of Radiation Oncology, University of Western Ontario, London Regional Cancer Centre, Canada. chris.leighton@lrcc.on.ca
C C
CC
Leighton
D T
DT
Shum
D000328:Adult; D005260:Female; D005870:Giant Cell Tumors / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D010010:Osteoclasts / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery*