Pseudoexfoliatio capsulae and endothelin-1 plasma levels.
The authors found an increase of endothelin-1 (ET-1) plasma levels in patients with pseudoexfoliatio syndrome (PXS): 2.730 +/- 0.224 pg/ml vs 1.420 +/- 0.30S pg/ml. With Color Doppler Imaging (CDI) they found in PXS patients a decrease of peak systolic velocity values in the posterior ciliary arteries that were 12.725 +/- 2.536 cm/sec vs 15.450 +/- 3.173 cm/sec (p < 0.049) while the resistance values were increased 0.640 +/- 0.051 vs 0.548 +/- 0.058 (p < 0.001). The increase of ET-1 plasma levels may assess the vasospasm and uveal tissue hypoxia.
Cellini
M
M
Institute of Ophthalmology, University of Bologna.
Possati
G L
GL
Rossi
A
A
Moretti
M
M
Torregiani
A
A
D000368:Aged; D001783:Blood Flow Velocity; D019842:Ciliary Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology; D019332:Endothelin-1 / Q000097:blood*; D017889:Exfoliation Syndrome / Q000097:blood* / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009880:Ophthalmic Artery / Q000000981:diagnostic imaging / Q000503:physiopathology; D018615:Ultrasonography, Doppler, Color
D019332:Endothelin-1