Development of spectral colour banding in cytogenetic analysis.
We developed a novel chromosome banding technique-spectral colour banding (SCAN). With this technique we displayed a multicolour banding pattern that almost entirely correlated with the corresponding G-banding pattern. With SCAN analysis we could identify the chromosome-band origin of double minute chromosomes in gastric cancer. Our preliminary use of this technique suggests that it has significant clinical applications for cytogenetic analysis.
Kakazu
N
N
Ashihara
E
E
Hada
S
S
Ueda
T
T
Sasaki
H
H
Terada
M
M
See
T A
TA
D018279:Carcinoma, Signet Ring Cell / Q000235:genetics; D002871:Chromosome Banding / Q000379:methods*; D002879:Chromosomes, Human, Pair 10; D003116:Color; D005453:Fluorescence; D006801:Humans; D008297:Male; D008875:Middle Aged; D009693:Nucleic Acid Hybridization; D013274:Stomach Neoplasms / Q000235:genetics