[Effects of bioflavonoids on the toxicity of T-toxin in rats. A biochemical study].
The enrichment of a diet of rats by flavonoids of milk thistle, Silybum marianum, reduced toxicity of T-2 toxin and was accompanied by reduction of a degree of change of total and nonsedimentable activity of lysosomal enzymes and microsomal xenobiotic metabolizing enzymes.
Kravchenko
L V
LV
Avren'eva
L I
LI
Tutel'ian
V A
VA
D000704:Analysis of Variance; D000818:Animals; D001192:Arylsulfatases / Q000097:blood / Q000378:metabolism; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism; D004032:Diet; D005419:Flavonoids / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008247:Lysosomes / Q000187:drug effects / Q000201:enzymology; D008361:Mannosidases / Q000097:blood / Q000378:metabolism; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology; D051381:Rats; D013605:T-2 Toxin / Q000037:antagonists & inhibitors* / Q000633:toxicity; D013950:Thymus Gland / Q000187:drug effects; D015262:Xenobiotics / Q000378:metabolism; D001616:beta-Galactosidase / Q000097:blood / Q000378:metabolism
D005419:Flavonoids; D015262:Xenobiotics; D002265:Carboxylic Ester Hydrolases; D001192:Arylsulfatases; D008361:Mannosidases; D001616:beta-Galactosidase; D013605:T-2 Toxin