Effect of clinoptilolite on performance of broiler chickens during experimental aflatoxicosis.
1. The amelioration of aflatoxicosis in broiler chickens was examined by feeding 2 concentrations of natural zeolite (clinoptilolite). Clinoptilolite (CLI), incorporated into the diet at 15 and 25 g/kg, was evaluated for its ability to reduce the deleterious effects of 2.5 mg total aflatoxin (AF; 76.40% AFB1, 16.12% AFB2, 6.01% AFG1 and 1.47% AFG in diet on growing broiler chicks from 1 to 21 d of age. A total of 360 broiler chicks were divided into 6 treatment groups (6 replicates of 10 broilers each): control, AF, CLI (15 g/kg), AF plus CLI (15 g/kg), CLI (25 g/kg), and AF plus CLI (25 g/kg).   2. Compared to controls, the treatment had significantly decreased body weight gain from week 1 onwards. The adverse effect of AF on food consumption (8.0%) and food conversion ratio (8.3%) was also shown over the entire 21-d feeding period.   3. The addition of CLI (15 g/kg) to an AF-containing diet significantly reduced the deleterious effects of AF on food consumption and body weight gain. Food conversion ratio was also slightly improved by adding CLI (15 g/kg) to AF-containing diets. Food consumption, body weight gain and food conversion ratio values were rendered numerically intermediate between AF and control groups by the addition of CLI (25 g/kg) to the AF-containing diet.   4. The addition of CLI (both 15 and 25 g/kg) to the AF-free diet did not produce any significant changes compared with the controls, except for decreased total food consumption in the CLI (25 g/kg)-alone group.   5. These results suggest that CLI (15 g/kg) addition effectively diminished the detrimental effects of AF on the values investigated. Also, the lower dietary concentration of CLI (15 g/kg) was more effective than the greater concentration against the adverse effects of AF on the variables investigated in this study.
Departments of Phaarmacology and Toxicology University of Selçuk, Konya, Turkey.
H
H
Oğuz
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Kurtoğlu
D000348:Aflatoxins / Q000633:toxicity*; D000821:Animal Feed / Q000633:toxicity; D000818:Animals; D001835:Body Weight; D002645:Chickens / Q000254:growth & development / Q000502:physiology*; D005260:Female; D008297:Male; D011897:Random Allocation; D015430:Weight Gain; D017641:Zeolites / Q000008:administration & dosage*
D000348:Aflatoxins; C083175:clinoptilolite; D017641:Zeolites