Parovirus B19 infection in an HIV-infected patient with febrile pancytopenia and acute hepatitis.
The case of a 34-year-old male patient with HIV infection referred for severe febrile pancytopenia is reported. Clinical and laboratory evaluations revealed acute hepatitis B infection and concomitant parvovirus B19 infection. The patient died just before treatment with immune globulin was to be administered. Parvovirus B19 has been found to cause a wide variety of hematologic disorders such as neutropenia, thrombocytopenia, pancytopenia, and hemophagocytic syndrome. The role of parvovirus B19 in the pathogenesis of bone marrow or liver involvement is briefly discussed.
Alliot
C
C
Division of Internal Medicine, Saint-Eloi University Hospital, Montpelllier, France.
Barrios
M
M
Taib
J
J
Brunel
M
M
D000208:Acute Disease; D000328:Adult; D015658:HIV Infections / Q000150:complications*; D006509:Hepatitis B / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D010198:Pancytopenia / Q000150:complications*; D010322:Parvoviridae Infections / Q000150:complications / Q000175:diagnosis*; D016732:Parvovirus B19, Human