Nonhomologous end-joining proteins are required for V(D)J recombination, normal growth, and neurogenesis.
Sekiguchi
J M
JM
Howard Hughes Medical Institute, Children's Hospital, Center for Blood Research, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
Gao
Y
Y
Gu
Y
Y
Frank
K
K
Sun
Y
Y
Chaudhuri
J
J
Zhu
C
C
Cheng
H L
HL
Manis
J
J
Ferguson
D
D
Davidson
L
L
Greenberg
M E
ME
Alt
F W
FW
D000818:Animals; D034961:Antigens, Nuclear; D017209:Apoptosis; D004265:DNA Helicases; D004260:DNA Repair; D004268:DNA-Binding Proteins / Q000172:deficiency / Q000235:genetics / Q000378:metabolism; D015322:Gene Rearrangement, B-Lymphocyte; D015329:Gene Rearrangement, T-Lymphocyte; D006128:Growth; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism; D000072200:Ku Autoantigen; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D009154:Mutation; D009420:Nervous System / Q000166:cytology / Q000196:embryology; D009687:Nuclear Proteins / Q000172:deficiency / Q000235:genetics; D010641:Phenotype; D011506:Proteins / Q000378:metabolism; D011995:Recombination, Genetic; D016159:Tumor Suppressor Protein p53 / Q000172:deficiency / Q000235:genetics
D034961:Antigens, Nuclear; D004268:DNA-Binding Proteins; D018398:Homeodomain Proteins; D009687:Nuclear Proteins; D011506:Proteins; C499308:Rag2 protein, mouse; D016159:Tumor Suppressor Protein p53; C064655:V(D)J recombination activating protein 2; C101467:XRCC4 protein, human; C064658:RAG-1 protein; D004265:DNA Helicases; C106893:XRCC5 protein, human; C000606509:Xrcc6 protein, human; C000606510:Xrcc6 protein, mouse; D000072200:Ku Autoantigen