Milk protein-derived peptide inhibitors of angiotensin-I-converting enzyme.
Numerous casein and whey protein-derived angiotensin-I-converting enzyme (ACE) inhibitory peptides/hydrolysates have been identified. Clinical trials in hypertensive animals and humans show that these peptides/hydrolysates can bring about a significant reduction in hypertension. These peptides/hydrolysates may be classified as functional food ingredients and nutraceuticals due to their ability to provide health benefits i.e. as functional food ingredients in reducing the risk of developing a disease and as nutraceuticals in the prevention/treatment of disease.
FitzGerald
R J
RJ
Department of Life Sciences, University of Limerick, Limerick, Ireland.
Meisel
H
H
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000737:chemistry / Q000378:metabolism* / Q000627:therapeutic use; D000818:Animals; D001688:Biological Products / Q000627:therapeutic use; D019587:Dietary Supplements; D005502:Food; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D008322:Mammals / Q000502:physiology; D008894:Milk Proteins / Q000737:chemistry / Q000378:metabolism*; D007703:Peptidyl-Dipeptidase A / Q000378:metabolism / Q000502:physiology
D000806:Angiotensin-Converting Enzyme Inhibitors; D001688:Biological Products; D008894:Milk Proteins; D007703:Peptidyl-Dipeptidase A