Metastasis of cervical esophageal carcinoma to the temporal bone--a study of the temporal bone histology.
A 49-year-old male developed left abducens nerve palsy as a result of metastatic spread of carcinoma of the cervical esophagus to Rouviere's node and infiltration of the petrous portion of the left temporal bone. Postmortem temporal bone histology revealed that cancer cells had invaded the greater superficial petrosal nerve (GPN), lesser superficial petrosal nerve, tensor tympani muscle (TTM) and the skin covering the anterior wall of the left external auditory meatus. These findings suggest that the carcinoma metastasized from the cervical esophagus to Rouviere's node and directly invaded the middle cranial fossa and then the temporal bone, and further infiltrated the middle ear via perineural invasion.
Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113-0033, Tokyo, Japan. yutakaimauchi@msn.com
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Y
Imauchi
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Kaga
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K
Nibu
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N
Sakuma
Y
Y
Iino
K
K
Kodera
D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011859:Radiography; D012888:Skull Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D013701:Temporal Bone / Q000473:pathology