Effects of exhausting exercise and catecholamines on K+ balance, acid-base status and blood respiratory properties in carp.
The potential role of adrenergic mechanisms in the recovery of potassium balance and acid-base status following 5 min of exhausting exercise was studied in carp. The extracellular metabolic H+ load after exercise matched the lactate load, suggesting similar release rates of H+ and lactate from white muscle. Blockage of alpha-adrenoceptors by phentolamine or beta-adrenoceptors by propranolol neither influenced absolute magnitudes nor recovery kinetics of extracellular H+ and lactate loads. The arterial oxygen tension increased following exercise, but blood oxygen transport was not improved via a red cell beta-adrenergic response or modulation of the red cell nucleoside triphosphate content. Exercise induced an increase in extracellular [K+] which was corrected within 30-60 min of recovery. The recovery of K+ balance was not influenced by blockage of adrenergic receptors. Red cell [K+] changed only insignificantly following exercise, whereby a possible function of the red cells as a temporary depository for K+ during the extracellular hyperkalaemia could not be established. The minimal influence of catecholamines on the measured parameters during recovery from exercise was supported by an absence of change in these parameters upon adrenaline injection in resting carp.
Institute of Biology, Odense University, Denmark. koldkjaer@dou.dk
P K
PK
Knudsen
F B
FB
Jensen
D000136:Acid-Base Equilibrium / Q000502:physiology*; D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D002245:Carbon Dioxide / Q000097:blood; D002347:Carps / Q000502:physiology*; D002395:Catecholamines / Q000502:physiology*; D002712:Chlorides / Q000097:blood; D004912:Erythrocytes / Q000378:metabolism; D005110:Extracellular Space / Q000378:metabolism; D006859:Hydrogen / Q000097:blood; D019344:Lactic Acid / Q000097:blood; D009043:Motor Activity / Q000502:physiology*; D010100:Oxygen / Q000097:blood*; D010646:Phentolamine / Q000494:pharmacology; D010807:Physical Endurance; D011188:Potassium / Q000378:metabolism*; D011433:Propranolol / Q000494:pharmacology
D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D002395:Catecholamines; D002712:Chlorides; D002245:Carbon Dioxide; D019344:Lactic Acid; D006859:Hydrogen; D011433:Propranolol; D011188:Potassium; D010100:Oxygen; D010646:Phentolamine