Role of CTLA 4-Ig on induction of unresponsiveness to multiple minor alloantigens.
LPS blasts inhibited graft rejection in multiple minor incompatible strain combinations but not in presensitized animals or in major histoincompatible combinations.
Department of Surgery, University of Toronto, Canada.
R M
RM
Gorczynski
F
F
Kiziroglu
D000069594:Abatacept; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000494:pharmacology*; D001402:B-Lymphocytes / Q000276:immunology*; D060908:CTLA-4 Antigen; D006084:Graft Rejection / Q000276:immunology*; D006085:Graft Survival / Q000276:immunology*; D018796:Immunoconjugates; D007376:Interleukin-2 / Q000032:analysis; D015847:Interleukin-4 / Q000032:analysis; D008213:Lymphocyte Activation; D017710:Lymphocyte Transfusion; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D015778:Minor Histocompatibility Antigens / Q000276:immunology; D011993:Recombinant Fusion Proteins / Q000494:pharmacology; D016038:Skin Transplantation / Q000276:immunology*; D013045:Species Specificity; D013154:Spleen / Q000276:immunology; D014184:Transplantation, Homologous
D015703:Antigens, CD; D000943:Antigens, Differentiation; D060908:CTLA-4 Antigen; C556707:Ctla4 protein, mouse; D018796:Immunoconjugates; D007376:Interleukin-2; D015778:Minor Histocompatibility Antigens; D011993:Recombinant Fusion Proteins; D015847:Interleukin-4; D000069594:Abatacept