Prevention, diagnosis, and treatment of venous thromboembolic complications of gynecologic surgery.
Deep vein thrombosis and pulmonary embolism, collectively referred to as venous thromboembolic events, are a source of significant morbidity and mortality after gynecologic surgical procedures. In this literature review the advantages and disadvantages of various preventive measures for deep venous thrombosis, including low-molecular-weight heparins, are discussed. The most appropriate prophylactic methods for patients in varying risk categories are recommended. Current methods of diagnosing deep venous thrombosis and pulmonary embolism, including ultrasonography, venography, ventilation-perfusion scan, helical computed tomographic scan, and D -dimer measurement are then discussed. Finally, treatment modalities for deep venous thrombosis and pulmonary embolism, including heparin, low-molecular-weight heparin, warfarin, and thrombolytic therapy, are detailed.
Division of Gynecology, University of Florida College of Medicine, Gainesville, FL 32610-0294, USA.
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Davis
D000328:Adult; D001458:Bandages; D001779:Blood Coagulation Factors / Q000032:analysis; D004434:Early Ambulation; D005260:Female; D005831:Genital Diseases, Female / Q000601:surgery*; D006493:Heparin / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications; D011312:Pressure; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000517:prevention & control* / Q000628:therapy; D012307:Risk Factors; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000517:prevention & control* / Q000628:therapy
D001779:Blood Coagulation Factors; D006493:Heparin