Combined tall cell carcinoma and Hürthle cell carcinoma (collision tumor) of the thyroid.
Tall cell carcinoma and Hürthle cell carcinoma are 2 aggressive forms of differentiated follicular-derived thyroid carcinomas. We present a case where these malignant tumors of thyroid coexisted. The tumor originated in the thyroid as a mixed tumor and metastasized as a tall cell tumor to the lymph nodes and as a Hürthle cell carcinoma to lungs. The coexistence of these tumor types is rare and sheds light on the histogenesis of Hürthle cell tumors and the metastatic behavior of combined tumors.
Department of Pathology and Laboratory Medicine, 6 Founders Pavilion, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA. baloch@mail.med.upenn.edu
Z W
ZW
Baloch
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S
Mandel
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LiVolsi
D000230:Adenocarcinoma / Q000473:pathology* / Q000628:therapy; D000368:Aged; D002291:Carcinoma, Papillary / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000556:secondary; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology / Q000601:surgery; D008207:Lymphatic Metastasis; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000628:therapy; D011878:Radiotherapy; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000628:therapy; D013965:Thyroidectomy; D013974:Thyroxine / Q000627:therapeutic use
D007457:Iodine Radioisotopes; D013974:Thyroxine