Efficiencies of genes and accuracy of tree-building methods in recovering a known Drosophila genealogy.
Phylogenetic hypotheses generated from seven Drosophila mitochondrial genomes support a well-corroborated genealogy with a single evolutionary history. These mitochondrial data form a model system for investigating the efficiency of genes and accuracy of different tree-building methods in recovering a well-supported genealogy. We consider 15 genes (13 protein-coding and 2 rRNAs) and 83 tree-building methods (27 distance, 4 parsimony, 50 maximum likelihood, and 2 Bayesian). Among the 15 genes examined, ND4 recovered the true genealogy most efficiently (82 out of 83 methods). Generally, maximum likelihood models enforcing a clock most accurately reclaim the true genealogy. Surprisingly, however, this method fails to recover the well-supported topology for more than half of the genes. Additional studies are required to test the generality of the results presented here.
Field Museum, 1400 S. Lake Shore Drive, Chicago, IL 60605-2496, USA.
J E
JE
Steinbachs
N V
NV
Schizas
J W
JW
Ballard
D000818:Animals; D001499:Bayes Theorem; D004272:DNA, Mitochondrial / Q000235:genetics; D004330:Drosophila / Q000235:genetics*; D005260:Female; D017344:Genes, Insect; D016013:Likelihood Functions; D008957:Models, Genetic; D010802:Phylogeny
D004272:DNA, Mitochondrial