Oxygenated sesquiterpenoids from a nonpoisonous sardinian chemotype of giant fennel (Ferula communis).
The roots of the nonpoisonous chemotype of giant fennel (Ferula communis) from Sardinia afforded a novel cadinanetriol (1), whose structure was established by spectroscopic data and confirmed by synthesis from the E,E-Delta (1(10),5) germacradiene allohedycariol. A number of known compounds were also identified. Despite the lack of morphological differences, a broad chemical diversity exists within giant fennel, underlying the contrasting data on its poisonous properties.
Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, Via Giuria 9, 10125 Torino, Italy. appendin@pharm.unito.it
G
G
Appendino
G
G
Cravotto
O
O
Sterner
M
M
Ballero
D005309:Ferula / Q000737:chemistry*; D007558:Italy; D010946:Plants, Medicinal; D010947:Plants, Toxic; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D013045:Species Specificity
D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C429608:cadinanetriol