A simple method for aligning many protein sequences.
A simple extension of the Needleman and Wunsch algorithm for aligning pairs of protein sequences allows it to be used for the efficient generation of very large multiple-sequence alignments whose members are similar. This technique could have applications in a broad range of high-volume genomics projects.
Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow G1 1XL Scotland, United Kingdom. cbas25@strath.ac.uk
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D000465:Algorithms; D000595:Amino Acid Sequence; D000818:Animals; D003573:Cytochrome b Group / Q000737:chemistry / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D011506:Proteins / Q000737:chemistry* / Q000235:genetics; D016415:Sequence Alignment / Q000379:methods* / Q000706:statistics & numerical data; D017386:Sequence Homology, Amino Acid
D003573:Cytochrome b Group; D011506:Proteins