Pericarditis after allogeneic peripheral blood stem cell transplantation caused by Legionella pneumophila (non-serogroup 1).
A case of Legionella pericarditis caused by a Legionella pneumophila isolate other than serogroup 1 is reported in a 59-year-old man after allogeneic peripheral blood stem cell transplantation. On admission a 5 mm pericardial effusion was detected on echocardiography. Antibodies were detected against L. pneumophila serogroups 7 to 14 using the antigen pool and against serogroup 12 alone. Antibodies were not detected against the serogroup 1 to 6 antigen pool. The patient's clinical condition improved dramatically after treatment with clarithromycin and an echocardiography revealed the total disappearance of the pericardial effusion.
Schaumann
R
R
Institute for Medical Microbiology and Epidemiology of Infectious Diseases, University of Leipzig, Germany. schaur@medizin.uni-leipzig.de
Pönisch
W
W
Helbig
J H
JH
Hegenbart
U
U
Ackermann
G
G
Hofmann
J
J
Niederwieser
D
D
Rodloff
A C
AC
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000032:analysis; D017291:Clarithromycin / Q000627:therapeutic use; D004452:Echocardiography; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D016952:Legionella pneumophila / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010490:Pericardial Effusion / Q000382:microbiology*; D010493:Pericarditis / Q000188:drug therapy / Q000209:etiology*; D012703:Serotyping; D014184:Transplantation, Homologous
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D017291:Clarithromycin