Which lead for Q-T interval measurements?
There are several Q-T interval measures (individual lead, mean Q-T interval or Q-T dispersion) from a 12-lead ECG. Which should be used? As the ECG provides twelve different measures of the heart's "true" Q-T interval, and as, "a priori", no one measure is any better or worse than any other measure at estimating the "true" Q-T interval, the best measure is the average of these twelve measures, i.e., the mean Q-T interval. The best single lead to measure the Q-T interval is the lead that relates most closely to the mean Q-T interval which in 49 subjects with cardiac diseases was lead V(3), then lead II. The longest lead Q-T interval relates poorly to the mean and to the individual lead Q-T intervals and therefore carried information different to and quite unique from these measures. This unique information is Q-T dispersion which relates well to the longest lead Q-T interval (r = 0.71, p < 0.001).
Davey
P P
PP
Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford OX3 9DU, UK. Ppdavey@aol.com
D000704:Analysis of Variance; D001145:Arrhythmias, Cardiac / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003627:Data Interpretation, Statistical; D004562:Electrocardiography / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D008875:Middle Aged; D011859:Radiography