A prospective study of contact lens wear in diabetes mellitus.
A prospective, controlled, observer-masked study was conducted to investigate the suitability of contact lenses for patients with diabetes mellitus. Forty diabetic patients and 40 non-diabetic control subjects were fitted with soft hydrogel contact lenses to be worn on a daily wear basis for 12 months. The ocular response was assessed using slit lamp biomicroscopy, ultrasonic pachometry, corneal aesthesiometry and visual acuity measures. Compared to non-diabetic subjects, diabetic patients displayed significantly reduced corneal transparency, variable vision and reduced comfort with the contact lenses (p < 0.05). There were no significant differences between the two groups with respect to ocular hyperaemia, corneal staining, corneal thickness, corneal sensitivity or high contrast visual acuity. Contrary to previous reports, the response of the diabetic eye to contact lenses--as observed clinically--does not differ appreciably from that of the non-diabetic eye. These results suggest that current generation daily wear soft contact lenses can be a viable mode of vision correction for diabetic patients.
European Centre for Contact Lens Research, Department of Optometry and Neuroscience, University of Manchester Institute of Science and Technology, P.O. Box 88, Manchester M60 1QD, UK. clare.odonnell@umist.ac.uk
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O'Donnell
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Efron
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Boulton
D000328:Adult; D016022:Case-Control Studies; D003261:Contact Lenses; D000075202:Contraindications; D003315:Cornea / Q000166:cytology; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000503:physiopathology; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D008297:Male; D017060:Patient Satisfaction; D011446:Prospective Studies; D014792:Visual Acuity / Q000502:physiology
D006442:Glycated Hemoglobin