Gynecologic malignancies accompanied by benign hormone-dependent diseases.
OBJECTIVE
To investigate the correlation between benign gynecologic diseases and hormone-dependent malignancies such as endometrial carcinoma in postmenopausal women.


METHODS
We retrospectively analyzed the prevalence of myoma uteri and adenomyosis uteri in 136 cases of endometrial carcinomas. We used 222 uterine prolapse cases as controls.


RESULTS
The results showed that 21.6% and 9.9% of healthy postmenopausal women (control) had myoma uteri and adenomyosis uteri, respectively, after the cessation of menses. However, postmenopausal women with endometrial carcinomas had a 1.5- to 2-fold higher prevalence, respectively, for myoma uteri and adenomyosis uteri as compared with the postmenopausal control women.


CONCLUSIONS
There was a higher prevalence of myoma uteri and adenomyosis uteri in postmenopausal patients with endometrial carcinomas than in the control population.
Koshiyama
M
M
Department of Obstetrics and Gynecology, Tenri Hospital, Nara, Japan.
Morita
Y
Y
Fujii
H
H
Kobashi
Y
Y
Yoshida
M
M
D000368:Aged; D016889:Endometrial Neoplasms / Q000150:complications*; D004715:Endometriosis / Q000150:complications*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000150:complications*; D008875:Middle Aged; D017698:Postmenopause; D012189:Retrospective Studies; D014594:Uterine Neoplasms / Q000150:complications*