Hepatic resection for metastatic tumors from noncolorectal carcinoma.
OBJECTIVE
The role of liver resection for hepatic metastases from noncolorectal carcinomas has yet to be clarified. The present study examines a single institutional experience of hepatic resection for noncolorectal metastases.


METHODS
From January 1987 to March 1999, 14 patients underwent curative resection for liver metastases from noncolorectal carcinomas. Records of these patients were reviewed.


RESULTS
Resections were performed for liver metastases from gastric cancers (n = 8), pancreatic cancers (n = 2), and cancers of bile duct, the papilla of Vater, kidney, and breast (n = 1, each). Six patients (5 with gastric cancers and 1 with pancreas cancer) presented with synchronous disease and 8 with metachronous disease. In the gastric cancer patients, there are 2 disease-free survivors (26 and 53 months) in the metachronous group, though all of the 5 patients with synchronous disease died within 29 months. All of the 4 patients with pancreatobiliary carcinomas died within 2 years. One case of breast cancer and another of renal cell cancer are alive without disease at 49 and 9 months, respectively.


CONCLUSIONS
For metastases from gastric cancers, better survival after hepatic resection is expected in metachronous cases than in synchronous cases. Hepatic resection may afford little benefit for patients with liver metastases from pancretobiliary cancers.
Department of Surgery, Institute of Clinical Medicine, Tsukuba University, Ten-nodai 1-1-1, Tsukuba, Ibaraki 305-8575, Japan.
Y
Y
Takada
M
M
Otsuka
K
K
Seino
H
H
Taniguchi
N
N
Koike
T
T
Kawamoto
K
K
Koda
S
S
Adachi
K
K
Yuzawa
M
M
Nozue
T
T
Todoroki
K
K
Fukao
D000368:Aged; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology; D015996:Survival Rate