Relationship between renal histology and later graft outcome.
We have created the chronic allograft damage index (CADI), which quantifies the early histopathological changes in renal allografts. In this study we showed that the CADI at 2 years after renal transplantation predicted the graft outcome 4 years later and that the CADI identified the risk group that proceeded to chronic rejection during subsequent years.
IV Department of Surgery, Helsinki University, Finland.
H
H
Isoniemi
J
J
Ahonen
B
B
Eklund
P
P
Häyry
K
K
Höckerstedt
L
L
Krogerus
K
K
Salmela
E
E
Taskinen
D001706:Biopsy; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000453:epidemiology; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000401:mortality / Q000473:pathology* / Q000502:physiology*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D015996:Survival Rate; D013997:Time Factors; D014184:Transplantation, Homologous; D016896:Treatment Outcome