Corpus callosum agenesis.
OBJECTIVE
The objectives are to analyse corpus callosum agenesis in children with various neurological problems in a hospital set-up, and to study the neurological and systemic abnormalities associated with this condition.


METHODS
The children with various neurological problems who underwent computerized tomography brain from January 1993 to December 1997, and were found to have corpus callosum agenesis, formed the subjects of this study. These children were examined for any syndromic association, congenital infections or metabolic defects.


RESULTS
Out of 2164 children who underwent computerized tomography brain, 22 had corpus callosum agenesis (1%). Most cases were not syndromic and 64% were males. Epileptic disorders were noted in about one third of cases.


CONCLUSIONS
Corpus callosum agenesis is an important anomaly in children with neurodevelopment handicaps, usually detected by neuroradiology.
Division of Pediatric Neurology, Deparment of Child Health, Sultan Qaboos University Hospital, PO Box 35, Postal Code 123, Sultanate of Oman.
A
A
Chacko
R
R
Koul
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DK
Sankhla
D061085:Agenesis of Corpus Callosum; D002648:Child; D002675:Child, Preschool; D003337:Corpus Callosum / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D014057:Tomography, X-Ray Computed