Effects of xin mai tong capsule on vasoregulatory peptides in the patients of coronary heart disease.
In order to inquire into the therapeutic effects of Xin Mai Tong Capsule ([symbol: see text]) on coronary heart disease with myocardial ischemia, 40 patients were randomly divided into two groups (Xin Mai Tong group and the control group). The plasma endothelin (ET) levels in the two groups of patients were markedly higher than that of the healthy people (P < 0.001), and the calcitonin gene related peptide (CGRP) was similar to that of the healthy people (P > 0.05). After treatment, ET and symptomatic scores in the two groups decreased markedly (P < 0.01), and their S-T segments were elevated obviously (P < 0.01). But the decrease of ET and symptomatic scores and elevation of S-T segment in Xin Mai Tong group were superior to those of the control group (P < 0.05-0.01). The CGRP level in the control group did not vary obviously post-treatment, but it increased markedly (P < 0.01) with the addition of Xin Mai Tong Capsule in Xin Mai Tong group.
First Hospital Affiliated to Sun Yat-sen University of Medical Sciences, Guangzhou 510080.
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D000368:Aged; D000787:Angina Pectoris / Q000097:blood / Q000188:drug therapy; D000789:Angina, Unstable / Q000097:blood / Q000188:drug therapy*; D015740:Calcitonin Gene-Related Peptide / Q000097:blood; D002214:Capsules; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D016232:Endothelins / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014665:Vasodilator Agents / Q000627:therapeutic use*
D002214:Capsules; D004365:Drugs, Chinese Herbal; D016232:Endothelins; D014665:Vasodilator Agents; D015740:Calcitonin Gene-Related Peptide