Plasmodium falciparum malaria.
A 13-year-old adolescent daughter of a missionary presented with fever and jaundice 1 week after returning from Africa. Examination of peripheral blood film revealed the diagnosis of Plasmodium falciparum infection. Therapy with oral quinine and doxycycline was curative. Diagnosis requires a travel history and a high index of suspicion. Because of the frequency of international travel, United States physicians need to be familiar with the presentation and management of imported P falciparum. Preparation for such travel must include careful counseling and optimal use of chemoprophylaxis.
Shetty
A K
AK
Department of Pediatrics, Stanford University Medical Center, Stanford, California, USA.
Steele
R W
RW
D000293:Adolescent; D000349:Africa / Q000453:epidemiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000962:Antimalarials / Q000627:therapeutic use; D004318:Doxycycline / Q000627:therapeutic use; D005260:Female; D006801:Humans; D016778:Malaria, Falciparum / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D066189:Missionaries; D011803:Quinine / Q000627:therapeutic use; D008921:Religious Missions; D014195:Travel; D014481:United States
D000900:Anti-Bacterial Agents; D000962:Antimalarials; D011803:Quinine; D004318:Doxycycline