A simple method for predicting bone fractures in PBC patients after liver transplantation.
We introduce a simple serum test to predict which patients will have bone problems after liver transplantation. The crosslinked part of collagen I (s-ICTP) was measured in 21 patients with primary biliary cirrhosis before transplantation. Those with postoperative fractures had increased pretransplant values of s-ICTP compared with those without fractures.
Fourth Department of Surgery, University of Helsinki, Finland.
K
K
Höckerstedt
H
H
Isoniemi
J
J
Risteli
L
L
Risteli
D015415:Biomarkers / Q000097:blood; D002119:Calcium Carbonate / Q000627:therapeutic use; D017610:Calcium Compounds / Q000627:therapeutic use; D003094:Collagen / Q000097:blood*; D024042:Collagen Type I; D005500:Follow-Up Studies; D050723:Fractures, Bone / Q000097:blood / Q000175:diagnosis* / Q000517:prevention & control; D006801:Humans; D007773:Lactates / Q000627:therapeutic use; D008105:Liver Cirrhosis, Biliary / Q000601:surgery; D016031:Liver Transplantation / Q000401:mortality / Q000502:physiology*; D008875:Middle Aged; D010455:Peptides / Q000097:blood*; D011183:Postoperative Complications / Q000175:diagnosis*; D011237:Predictive Value of Tests; D015996:Survival Rate; D013997:Time Factors
D015415:Biomarkers; D017610:Calcium Compounds; D024042:Collagen Type I; D007773:Lactates; D010455:Peptides; C052929:collagen type I trimeric cross-linked peptide; C110051:calcium lactate; D003094:Collagen; D002119:Calcium Carbonate