Synthesis of corollosporine, an antibacterial metabolite of the marine fungus Corollospora maritima.
Corollosporine [(+/-)-3-hexyl-3,7-dihydroxy-1(3H)-isobenzofuran-1-one], an antibacterial metabolite of the marine fungus, Corollospora maritima, was synthesized by four different routes from 3-hydroxyphthalic anhydride or 2-methoxybenzoic acid as the starting material to verify its proposed structure.
Department of Chemistry, Faculty of Science, Science University of Tokyo, Japan.
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Ohzeki
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Mori
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry; D001203:Ascomycota / Q000737:chemistry / Q000378:metabolism*; D015394:Molecular Structure; D010796:Phthalic Anhydrides / Q000138:chemical synthesis* / Q000737:chemistry
D000900:Anti-Bacterial Agents; D010796:Phthalic Anhydrides; C114766:corollosporine