Prolonged survival of murine cardiac allografts by treatment with the 4-amino analog of tetrahydrobiopterin.
Department of Transplant Surgery, University Hospital Innsbruck, Innsbruck, Austria. brandachergerald@hotmail.com
G
G
Brandacher
Y
Y
Zou
P
P
Obrist
W
W
Steurer
G
G
Werner-Felmayer
R
R
Margreiter
E R
ER
Werner
D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use*; D001708:Biopterins / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D006084:Graft Rejection / Q000378:metabolism / Q000517:prevention & control*; D006085:Graft Survival / Q000187:drug effects*; D016027:Heart Transplantation; D007371:Interferon-gamma / Q000378:metabolism; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D019001:Nitric Oxide Synthase / Q000378:metabolism; D052247:Nitric Oxide Synthase Type II; D013997:Time Factors; D014184:Transplantation, Homologous; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D000975:Antioxidants; D014409:Tumor Necrosis Factor-alpha; D001708:Biopterins; D007371:Interferon-gamma; D019001:Nitric Oxide Synthase; D052247:Nitric Oxide Synthase Type II; C496317:Nos2 protein, mouse; C003402:sapropterin