Dendritic cells and transmission of HIV-1.
Sexual transmission of HIV-1 requires that small amounts of virus at mucosal sites of inoculation gain access to replication-permissive cells. Recent observations have increased our understanding of the mechanisms by which this relatively inefficient virus can exploit the migratory nature of dendritic cells to establish infection within the host.
Nuffield Dept of Medicine, John Radcliffe Hospital, Oxford, UK OX3 9DU. asewell@gwmail.jr2.ox.ac.uk
A K
AK
Sewell
D A
DA
Price
D003713:Dendritic Cells / Q000276:immunology / Q000821:virology*; D015658:HIV Infections / Q000276:immunology* / Q000635:transmission; D015497:HIV-1 / Q000276:immunology*; D006801:Humans