A xanthate transfer radical process for the introduction of the trifluoromethyl group.
[reaction: see text]. S-Trifluoromethyl xanthates efficiently add to unactivated alkenes by a radical mechanism to give adducts with a trifluoromethyl group at the least hindered terminus of the olefin.
Institut de Chimie des Substances Naturelles, C.N.R.S., 91198 Gif-sur-Yvette, France.
F
F
Bertrand
V
V
Pevere
B
B
Quiclet-Sire
S Z
SZ
Zard