Ocular ferning during the menstrual cycle in healthy women.
OBJECTIVE
The aim of the study is to investigate whether tear ferning patterns change during different phases of the menstrual cycle.


METHODS
The tear ferning test was performed on twelve normal women of childbearing age at three day intervals throughout one complete menstrual cycle. Serum hormone levels (progesterone, estrogen, testosterone) were measured.


RESULTS
Eight women showed type I ferning, and the other four had type II ferning initially. These patterns did not change during the menstrual cycle. Serum hormone levels were all in the normal range. Since no change in ferning pattern was detected during the menstrual cycle, the ferning test can be done at any time in women.


CONCLUSIONS
This study showed no effect of different menstrual cycle phases on tear ferning patterns.
Department of Ophthalmology, Hacettepe University School of Medicine, Ankara, Turkey.
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Tatlipinar
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Gedik
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Irkeç
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Orhan
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Erdener
D000328:Adult; D003941:Diagnostic Techniques, Ophthalmological; D004967:Estrogens / Q000097:blood; D005136:Eye Proteins / Q000737:chemistry / Q000378:metabolism*; D005260:Female; D006801:Humans; D008597:Menstrual Cycle / Q000097:blood / Q000502:physiology*; D009093:Mucus / Q000737:chemistry; D011374:Progesterone / Q000097:blood; D013666:Tears / Q000737:chemistry / Q000378:metabolism*; D013739:Testosterone / Q000097:blood
D004967:Estrogens; D005136:Eye Proteins; C042434:tear proteins; D013739:Testosterone; D011374:Progesterone