Diltiazem downregulates IL-12 production by human dendritic cells.
Immunology Department, Istituto Superiore di Sanità, Roma, Italy.
A
A
D'Ambrosio
A
A
Bachetoni
E
E
Giacomini
M
M
Quaranta
F
F
Quintieri
D002121:Calcium Channel Blockers / Q000494:pharmacology*; D003713:Dendritic Cells / Q000187:drug effects* / Q000378:metabolism; D004110:Diltiazem / Q000494:pharmacology*; D015536:Down-Regulation; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007375:Interleukin-1 / Q000378:metabolism; D018664:Interleukin-12 / Q000378:metabolism*; D015850:Interleukin-6 / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014409:Tumor Necrosis Factor-alpha / Q000187:drug effects / Q000378:metabolism
D002121:Calcium Channel Blockers; D007375:Interleukin-1; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D018664:Interleukin-12; D004110:Diltiazem