[Motor activity and emotional response in the open field test in rats after pharmacologic stimulation or blockade of neuropeptides in terminals of primary sensory neurons].
Effects of high and low doses of capsaicin on the open-field behavioral patterns were examined in Wistar rats. The treated animals exhibited a significant increase in locomotion, grooming, and exploratory activity.
Zhukova
E M
EM
Institute of Physiology, Russian Academy of Sciences, Siberian Branch, Novosibirsk.
D000818:Animals; D002211:Capsaicin / Q000008:administration & dosage / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004644:Emotions / Q000187:drug effects* / Q000502:physiology; D005106:Exploratory Behavior / Q000187:drug effects / Q000502:physiology; D006120:Grooming / Q000187:drug effects / Q000502:physiology; D008297:Male; D009043:Motor Activity / Q000187:drug effects* / Q000502:physiology; D009475:Neurons, Afferent / Q000187:drug effects* / Q000502:physiology / Q000648:ultrastructure; D009479:Neuropeptides / Q000378:metabolism*; D017729:Presynaptic Terminals / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar
D009479:Neuropeptides; D002211:Capsaicin