Second-order selection in bacterial evolution: selection acting on mutation and recombination rates in the course of adaptation.
The increase in genetic variability of a population can be selected during adaptation, as demonstrated by the selection of mutator alleles. The dynamics of this phenomenon, named second-order selection, can result in an improved adaptability of bacteria through regulation of all facets of mutation and recombination processes.
Inserm E9916, Faculté de médecine Necker Enfants Malades, Université Paris V, France. tenaillo@necker.fr
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Radmian
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D000222:Adaptation, Physiological / Q000235:genetics*; D001419:Bacteria / Q000235:genetics* / Q000254:growth & development; D005075:Biological Evolution; D009154:Mutation / Q000235:genetics*; D011995:Recombination, Genetic / Q000235:genetics; D012641:Selection, Genetic