[A method of evaluating the stationary rate of gene migration (a cartographic approach)].
A method of geographic mapping of the stationary (limiting) gene migration rate has been developed. The method is based on approximation of the empirical distribution of gene frequencies by a theoretical steady-state distribution. The maximum likelihood method and the chi 2 minimization method are used to obtain consistent estimations of the gene migration rate as a parameter of the steady-state distribution. The new method makes it possible to determine the geographical distribution of the ratio between the properties of the population migration structure described by the stepping-stone and island models and to construct a geographical map of chi 2 values. This map approximately reflects the distribution of natural selection pressure on the gene pool if genetic processes are quasisteady.
Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 117809 Russia. evsyukov@vigg.ru
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Evsiukov
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Zhukova
D005787:Gene Frequency; D005788:Gene Pool; D005843:Geography; D006801:Humans; D016013:Likelihood Functions; D012641:Selection, Genetic