Methotrexate-treated arthritis and lymphoproliferative disease--coincidence only?
This paper describes four patients with inflammatory joint diseases treated with methotrexate who developed lymphoma either of unusual type or with bizarre clinical features. The pathogenesis of this unusual condition is discussed and the difficulty in differentiating it from the features of the initial disease is emphasised.
B. Shine Department of Rheumatology, Rambam Medical Center, The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa.
Y
Y
Braun-Moscovici
D
D
Schapira
A
A
Balbir-Gurman
A M
AM
Nahir
D000368:Aged; D001168:Arthritis / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000209:etiology*; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use*; D008875:Middle Aged
D008727:Methotrexate