Treatment of multiple evanescent white dot syndrome with cyclosporine.
OBJECTIVE
To report the seven-year follow-up of a patient with multiple evanescent white-dot syndrome (MEWDS).


METHODS



METHODS
A 46-year-old woman presented recurrent episodes of bilateral MEWDS.


RESULTS
During the seven-year follow-up there were nine episodes of MEWDS. After four bouts in the first two, cyclosporine therapy was started. During two years of treatment there were no recurrences except when the dose was reduced or discontinued.


CONCLUSIONS
The etiology of MEWDS is still unknown but the absence of new episodes during cyclosporine treatment and the recurrence immediately after decreasing or discontinuing the drug suggests an autoimmune origin, with the involvement of cellular immunity in the pathogenic process.
Department of Ophthalmology, Ramon y Cajal University Hospital, Madrid, Spain. Figueroa@lander.es
M S
MS
Figueroa
E
E
Ciancas
B
B
Mompean
C
C
Quereda
D016572:Cyclosporine / Q000627:therapeutic use*; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008875:Middle Aged; D012164:Retinal Diseases / Q000188:drug therapy*; D013577:Syndrome
D007166:Immunosuppressive Agents; D016572:Cyclosporine