Clinical evaluation of hypercoagulable states.
Although thromboembolic disease associated with primary thrombophilic conditions most often presents before age 50 years, older adults can be affected by such disorders. This article addresses congenital and acquired prothrombotic states, with specific attention to the likelihood of such disorders occurring in the geriatric patient population. Recommendations for testing and therapy are reviewed.
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Divisions of Geriatric Medicine and Hematology, Department of Medicine, Montefiore Medical Center, Bronx, New York, USA.
D000368:Aged; D000369:Aged, 80 and over; D020152:Antithrombin III Deficiency; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D011379:Prognosis; D011486:Protein C / Q000378:metabolism; D011488:Protein Deficiency / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D017293:Protein S / Q000378:metabolism; D018570:Risk Assessment; D013923:Thromboembolism / Q000453:epidemiology / Q000209:etiology*; D019851:Thrombophilia / Q000150:complications* / Q000175:diagnosis* / Q000453:epidemiology
D011486:Protein C; D017293:Protein S