[Contribution of immunofixation and laser nephelometry in the diagnosis of monoclonal immunoglobulinopathy].
Immunological diagnosis of principal's monoclonal gammapathies [Waldenström's macroglobulinemia and multiple myeloma], used classically electrophoresis and immunoelectrophoresis analysis (AIE) for detection of monoclonal components. Although its specificity and sensibility, the last method stays a long analysis with critical interpreting from time to time. The present study reports results obtained with 100 sera from subjects with these diseases when using immunofixation and nephelometry-laser witch tests amounts of IgG, IgA and IgM and kappa/lambda--ratio both methods together, which are simpler and more faster than AIE.
Service d'Immunologie-Institut Pasteur d'Algérie.
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Djenouhat
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Mehdi
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Abbadi
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007159:Immunologic Tests; D007834:Lasers; D008297:Male; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry / Q000379:methods; D010265:Paraproteinemias / Q000175:diagnosis* / Q000276:immunology