The BH4 domain of A1, an anti-apoptotic bcl family gene, is necessary and sufficient for its antiinflammatory function in endothelial cells.
Rocha
E
E
Immunobiology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Mahiou
J
J
Badrichani
A Z
AZ
Stroka
D M
DM
Ferran
C
C
D000818:Animals; D017209:Apoptosis / Q000235:genetics; D002417:Cattle; D002874:Chromosome Mapping; D004730:Endothelium, Vascular; D004789:Enzyme Activation; D006801:Humans; D016328:NF-kappa B / Q000378:metabolism; D010957:Plasmids / Q000235:genetics; D016133:Polymerase Chain Reaction; D011519:Proto-Oncogenes / Q000235:genetics*; D014162:Transfection / Q000379:methods; D014657:Vasculitis / Q000235:genetics*
D016328:NF-kappa B