Hemolytic uremic syndrome after capnocytophaga canimorsus (DF-2) septicemia.
A 66-year-old man developed a hemolytic uremic syndrome (HUS) with acute renal failure, thrombocytopenia, fragmented red cells in the blood film and elevated serum LDH following a capnocytophaga canimorsus (DF-2) infection after a dog bite. He was treated with antibiotics, plasmapheresis and hemodialysis. Although hematologic values improved, the patient remained hemodialysis-dependent for six months. In the literature several cases of renal failure following capnocytophaga canimorsus septicemia have been described, caused by hypotension or disseminated intravascular coagulation (DIC). In our patient there were no signs of hypotension or extensive DIC. A few case reports described HUS and thrombotic thrombocytopenic purpura (TTP) following DF-2 sepsis.
Mulder
A H
AH
Department of Internal Medicine, St Joseph Hospital, Veldhoven, The Netherlands.
Gerlag
P G
PG
Verhoef
L H
LH
van den Wall Bake
A W
AW
D000368:Aged; D000818:Animals; D001733:Bites and Stings; D002206:Capnocytophaga; D004285:Dogs; D016905:Gram-Negative Bacterial Infections / Q000150:complications*; D006463:Hemolytic-Uremic Syndrome / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008297:Male; D006435:Renal Dialysis