Novel molecular and immunotherapeutic strategies for lung cancer.
Lung cancer therapy in the future will be guided by specific characteristics of the individual tumor specimens. The molecular cancer phenotyping will allow for targeted approaches based on the amplification of oncogenes, lack of tumor suppressor genes, dysregulation of growth factors, and angiogenesis or matrix metalloproteinases. Specific immunotherapeutic approaches based on.
Departments of Surgery and Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, USA. passh@karmanos.org
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Pass
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Kalemkerian
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Bright
D020533:Angiogenesis Inhibitors / Q000627:therapeutic use; D017209:Apoptosis; D015972:Gene Expression Regulation, Neoplastic; D016147:Genes, Tumor Suppressor / Q000235:genetics; D015316:Genetic Therapy; D006801:Humans; D007167:Immunotherapy; D008175:Lung Neoplasms / Q000235:genetics / Q000276:immunology / Q000628:therapy*; D011519:Proto-Oncogenes / Q000235:genetics
D020533:Angiogenesis Inhibitors