Spectroscopic and electrochemical investigation of ternary complexes of D- or L-aspartic acid containing polyacrylamides-Cu(2+)-bovine serum albumin and their radio-stability.
D- or L-aspartic acid containing polyacrylamides were synthesized. Binary and ternary complex formation between these polymers with copper and bovine serum albumin was studied by spectroscopic and electrochemical measurement. Depending on the ratio of the polymer/copper and protein/polymer, the mixture exhibited water-soluble and insoluble character. A hypothetical structural scheme for the formation of ternary complexes is proposed. The effect of radiation on these complexes was also investigated.
TAEA, Cekmece Nuclear Research and Training Center, Department of Chemistry, PO Box 1, 34831 Havaalani, Istanbul, Turkey.
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D000180:Acrylic Resins / Q000737:chemistry* / Q000378:metabolism*; D001224:Aspartic Acid / Q000378:metabolism*; D002413:Cations, Divalent / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D003217:Conductometry; D003300:Copper / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D015394:Molecular Structure; D011485:Protein Binding; D011675:Pulse Radiolysis; D012710:Serum Albumin, Bovine / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013329:Structure-Activity Relationship; D000099166:Polyacrylamides
D000180:Acrylic Resins; D001224:Aspartic Acid; D002413:Cations, Divalent; D003300:Copper; D012710:Serum Albumin, Bovine; D000099166:Polyacrylamides