Cardiac surgery in the low-birth weight neonate. New approaches.
The LBW infant with congenital heart defects is likely to be at a higher risk for postoperative death and complications than their normal-sized counterparts because of the effects of prematurity and other organ system dysfunction. Current experience, however, does not suggest that waiting to obtain an arbitrary weight before surgery significantly improves outcome. Survival for low-weight infants undergoing complex repairs, such as those for interruption of the aortic arch and HLHS, is decreased compared with larger babies having the same operation at the same institution; however, the absolute survival rates are still quite acceptable. Weight alone should not be considered a contraindication to surgery for complex CHD. A careful investigation for the cause of the LBW must be undertaken (e.g., prematurity, infection, multiple congenital anomalies, and genetic abnormalities) and appropriate therapies initiated. The medical and surgical teams should collaborate to determine the optimal timing and type of surgery, with body weight being only of minor importance.
Cardiac Intensive Care Unit, Children's Hospital of Philadelphia, Pennsylvania, USA.
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Wernovsky
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Rubenstein
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Spray
D006330:Heart Defects, Congenital / Q000401:mortality / Q000601:surgery*; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D015931:Intensive Care, Neonatal; D008991:Monitoring, Physiologic; D010348:Patient Care Team / Q000458:organization & administration; D018743:Perinatal Care / Q000379:methods*; D019990:Perioperative Care / Q000379:methods*; D012121:Respiration, Artificial; D012307:Risk Factors; D016019:Survival Analysis; D016896:Treatment Outcome