Assessment of pulmonary perfusion using a subtracted HASTE image between diastole and systole.
The MR signal intensity change in the pulmonary parenchyma during the cardiac cycle was studied using HASTE sequence in volunteers. In addition, the potential to assess pulmonary perfusion abnormality by subtraction between diastolic and systolic HASTE images was tested in a pig model of pulmonary embolism. Signal intensity decreased in systole while it increased gradually in diastole. In a pig model with pulmonary embolism, subtracted images could identify the perfusion abnormality. Thus, subtraction of diastolic and systolic HASTE images has the potential to detect pulmonary perfusion abnormality. The technique may provide a new simple method for evaluating pulmonary perfusion.
Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA. hatabu@oasis.rad.upenn.edu
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D000328:Adult; D003971:Diastole; D005260:Female; D006801:Humans; D008297:Male; D023421:Models, Animal; D011655:Pulmonary Embolism / Q000175:diagnosis*; D013599:Systole