Dynamic model of amperometric biosensors. Characterisation of glucose biosensor output.
An integrated model for the characterisation of the output signal course of oxidase-bound amperometric biosensors is presented and evaluated in the case of glucose biosensors. This model integrates two earlier proposed models, the model of oxygen transducer-based biosensors, allowing the prediction of steady state parameters from the transient response and the dynamic signal lag model, characterising the electrochemical diffusion-limited sensors. The integrated model allows the characterisation of the whole biosensor signal output, originating from the output curve itself with errors less than 3% and no need to determine the system's geometrical, diffusion and partition parameters.
Rinken
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Institute of Physical Chemistry, Tartu University, Estonia. toonika@ut.ee
Tenno
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D015374:Biosensing Techniques; D005947:Glucose; D008956:Models, Chemical; D008962:Models, Theoretical
D005947:Glucose