Relative distribution of blood flow in rats during surface and submerged swimming.
The relative distribution of blood flow was investigated in conscious rats with a radiological imaging technique that utilizes technetium-99m ethyl cysteinate dimer (99mTc-ECD). The objective of the study was to determine the effects of locomotory activity on the distribution of blood flow during a dive response. We compared the relative distribution of systemic flow in rats at rest, surface swimming and during periods of voluntarily initiated underwater swimming. The pattern of blood flow differed considerably between the three groups of rats. In resting controls, blood flow was widely distributed throughout the whole body with the thoraco-abdominal region receiving the largest fraction of cardiac output. During surface swimming blood shifted towards the exercising limbs, while during underwater swimming systemic blood flow was largely restricted to the head and thorax. However, the active front and hind limbs were not rendered totally ischemic. This suggests that the demands of exercising skeletal muscle partially over-ride the peripheral vasoconstriction during asphyxic diving in conscious rats. Furthermore, relative blood flow to the head increased during underwater swimming, which supports the view that there is a preferential maintenance of blood flow to the brain.
Department of Physiology, University of Saskatchewan, Saskatoon, Canada. ollenberger@sask.usask.ca
G P
GP
Ollenberger
G
G
Matte
A A
AA
Wilkinson
N H
NH
West
D000005:Abdomen / Q000098:blood supply; D000818:Animals; D001775:Blood Circulation / Q000502:physiology*; D004242:Diving / Q000502:physiology*; D005121:Extremities / Q000098:blood supply; D006257:Head / Q000098:blood supply; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012039:Regional Blood Flow; D012146:Rest; D013550:Swimming / Q000502:physiology*; D013909:Thorax / Q000098:blood supply