Left ventricular assist device bridge to recovery: a review of the current status.
The use of the left ventricular assist device as a bridge to recovery represents a new phenomenon. This article focuses on bridge-to-recovery in the settings of myocarditis and dilated cardiomyopathy with a review of the hemodynamic, neurohormonal, physiologic, cellular, and molecular changes of recovery during left ventricular assist device support. Despite numerous markers of success, there is a disconnect from the limited clinical successes that are reviewed. The current status and future options to increase the chances of success are highlighted.
Kumpati
G S
GS
George M and Linda H Kaufman Center for Heart Failure, Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Ohio 44195, USA.
McCarthy
P M
PM
Hoercher
K J
KJ
D000328:Adult; D002311:Cardiomyopathy, Dilated / Q000601:surgery*; D005260:Female; D005544:Forecasting; D006353:Heart-Assist Devices / Q000639:trends; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000601:surgery*; D020127:Recovery of Function