[Comparative study of DNA-specific dyes of the indole and benzimidazole derivates].
Various models of complex formation of low-molecular ligands with DNA are considered. Using the Scatchard model, parameters of binding of fluorescent monophenylindole, monophenylbenzimidazole, and bisbenzimidazole dyes with calf thymus DNA were evaluated. By means of graphic (nonparametric) and correlation analysis, various spectral and complexation properties of these dyes in the presence of DNA are compared.
Sibirtsev
V S
VS
Central Research Institute of Roentgenology and Radiolology, Russian Ministry of Public Health, Leningradskaya ul., 70/4, Pesochny-2, St. Petersburg, 189646 Russia.
Garabadzhiu
A V
AV
Ivanov
S D
SD
D000818:Animals; D001562:Benzimidazoles; D004396:Coloring Agents; D004247:DNA / Q000737:chemistry*; D006801:Humans; D007211:Indoles; D008024:Ligands; D008956:Models, Chemical
D001562:Benzimidazoles; D004396:Coloring Agents; D007211:Indoles; D008024:Ligands; D004247:DNA