Therapy of status epilepticus in adults and children.
Clinical studies of the treatment of status epilepticus are extremely difficult to carry out, therefore a paucity of new clinical studies have been reported. Much of the progress regarding the therapy of status epilepticus has come from a better understanding of the epidemiology of status epilepticus and its consequences and from laboratory studies of experimental status. Status epilepticus has been used as an experimental tool to study epileptogenesis, but from such studies have come insights that can be applied to the therapy of status epilepticus itself. This review will focus on information from epidemiological, experimental, and clinical studies of status epilepticus, which may contribute to the improved treatment of this life-threatening disorder.
Treiman
D M
DM
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA. treiman@umdnj.edu
D000328:Adult; D000818:Animals; D000927:Anticonvulsants / Q000008:administration & dosage* / Q000009:adverse effects; D001921:Brain / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology*; D002648:Child; D002986:Clinical Trials as Topic; D004195:Disease Models, Animal; D006801:Humans; D013226:Status Epilepticus / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology*
D000927:Anticonvulsants