Facile and efficient sulfenylation method using quinone mono-O,S-acetals under mild conditions.
A novel sulfenylation method induced by aromatization of quinone mono-O,S-acetals is described. These sulfenylation reagents readily react with silyl enolethers or electron rich aromatic compounds to give sulfenylation products under mild conditions. In particular, O,S-acetal 2j, which possesses a pentafluorophenylthio function, is the most effective reagent from the standpoint of the adaptability for various substrates.
Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871, Japan.
M
M
Matsugi
K
K
Murata
K
K
Gotanda
H
H
Nambu
G
G
Anilkumar
K
K
Matsumoto
Y
Y
Kita