In vitro measurement accuracy of three-dimensional ultrasound.
OBJECTIVE
We sought to validate distance and volume measurements in three-dimensional (3-D) ultrasound images.


BACKGROUND
Even with the latest equipment, it is not known how accurate 3-D echocardiographic measurements are.


METHODS
Six models were imaged in ethanol solution and two within a tissue phantom using a mechanical rotation device rotating in 1 degrees intervals and a real-time 3-D scanner. Distance and volume measurements (n = 60) were performed in two-dimensional (2-D) and 3-D images using TomTec and InViVo software.


RESULTS
Distance measurements had a mean total error between 1.12% and 2.31% for Acuson (2.5 MHZ, 3 MHZ, and 4 MHZ) and Hewlett Parkard (HP) fusion frequencies h and m, HP fusion harmonic B in the axial, and between 3.5% and 4.9% in the lateral dimension. HP Harmonic A and B, Volumetrics (2.5 MHZ), and HP fusion Harmonic A exhibited significantly higher differences to reality with a mean difference between 5.1% and 8.9% in the axial and between 6.2% and 7.9% in the lateral direction. Axial 2-D measurements were not different from real dimensions except Volumetrics model 1. In the lateral axis, all imaging modalities were different from reality except the fusion harmonic modus B. Using the HP fusion frequency h and HP fusion Harmonic B-mode, volume measurements in 3-D images significantly underestimated reality, while Acuson's fundamental frequency 3.5 MHZ was not different from real volumes.


CONCLUSIONS
Three-dimensional visualization using different ultrasound settings results in different accuracy.
Heart Center Leipzig University, Germany. zotr@medizin.uni-leipzig.de
R J
RJ
Zotz
T
T
Trabold
A
A
Bock
C
C
Kollmann
D019560:Echocardiography, Three-Dimensional / Q000295:instrumentation*; D006801:Humans; D008954:Models, Biological; D019047:Phantoms, Imaging; D012680:Sensitivity and Specificity