Overexpression of A20 in endothelial cells of vascularized grafts creates a protective barrier against TNF- and FAS-mediated apoptosis.
Daniel
S
S
Immunobiology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Arvelo
M
M
Ferran
C
C
D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D017209:Apoptosis / Q000235:genetics / Q000502:physiology*; D002352:Carrier Proteins / Q000502:physiology; D020169:Caspases / Q000378:metabolism; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism*; D004789:Enzyme Activation; D053222:Fas Ligand Protein; D053200:Fas-Associated Death Domain Protein; D008562:Membrane Glycoproteins / Q000502:physiology*; D011506:Proteins / Q000235:genetics / Q000378:metabolism*; D013552:Swine; D014162:Transfection; D014409:Tumor Necrosis Factor-alpha / Q000502:physiology*; D016335:Zinc Fingers
D048868:Adaptor Proteins, Signal Transducing; D002352:Carrier Proteins; C505533:FADD protein, human; C505661:FASLG protein, human; D053222:Fas Ligand Protein; D053200:Fas-Associated Death Domain Protein; D008562:Membrane Glycoproteins; D011506:Proteins; D014409:Tumor Necrosis Factor-alpha; D020169:Caspases