Proteins of Mycobacterium bovis BCG induced in the Wayne dormancy model.
Oxygen starvation triggers the shiftdown of the obligate aerobe Mycobacterium bovis BCG to a state of dormancy. Two-dimensional electrophoresis showed a drastic up-regulation of the alpha-crystallin homolog, the putative response regulator Rv3133c, and the two conserved hypothetical proteins Rv2623 and Rv2626c in dormant bacilli.
Boon
C
C
Mycobacterium Laboratory, Institute of Molecular and Cell Biology, Singapore 117609, Republic of Singapore.
Li
R
R
Qi
R
R
Dick
T
T
D000332:Aerobiosis; D000693:Anaerobiosis; D001426:Bacterial Proteins / Q000096:biosynthesis*; D003459:Crystallins / Q000096:biosynthesis; D003470:Culture Media; D015180:Electrophoresis, Gel, Two-Dimensional; D008954:Models, Biological; D009163:Mycobacterium bovis / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D014158:Transcription, Genetic; D015854:Up-Regulation
D001426:Bacterial Proteins; D003459:Crystallins; D003470:Culture Media