Neurobrucellosis--a rare complication of renal transplantation.
Brucellosis is an intracellular bacterial infection contracted by consuming raw milk or by contact with infected cattle. Neurobrucellosis is a rather rare manifestation of brucellosis and has protean clinical presentations characterized by meningoencephalitis, myelitis, myelopathies, subarachnoid hemorrhage and psychiatric manifestations. A depressed immune status is believed to be a risk factor for developing neurobrucellosis. We report a case of neurobrucellosis in a patient 13 years after a cadaveric renal transplantation. Even though a Brucella organism was not isolated from body fluids she satisfied other criteria for establishing the diagnosis. Treatment with doxycycline and rifampin led to a clinical cure as well as to marked improvement in the Brucella titer.
Clinical Medical Services Department, Saudi Aramco-Dhahran Health Center, Saudi Aramco Medical Services Organization, Dhahran, Saudi Arabia.
B
B
Yousif
J
J
Nelson
D002006:Brucellosis / Q000209:etiology*; D020806:Central Nervous System Bacterial Infections / Q000209:etiology*; D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008875:Middle Aged; D009422:Nervous System Diseases