Creation of novel chiral cryptophanes by a self-assembling method utilizing a pyridyl-Pd(II) interaction.
[structure: see text]. This Letter demonstrates the molecular design of novel self-assembled chiral cryptophanes. Mediated by square-planar Pd(II) complexes, racemic pyridyl cyclotriveratrylene derivative rac-2 self-assembles into mixtures of racemic chiral cryptophanes and meso cryptophanes (1), which interconvert with each other, and the rates are remarkably enhanced by the addition of a slight excess of rac-2. On the other hand, optically resolved P-2 or M-2 self-assembles into the chiral cryptophane as the only product.
Department of Chemistry & Biochemistry, Graduate School of Engineering, Kyushu University, Fukuoka 812-8581, Japan.
Z
Z
Zhong
A
A
Ikeda
S
S
Shinkai
S
S
Sakamoto
K
K
Yamaguchi