Chernobyl fallout and outcome of pregnancy in Finland.
Possible effects of Chernobyl fallout on outcome of pregnancy in Finland were evaluated in a nationwide follow-up study. The outcomes were the rate of live births and stillbirths, pregnancy loss, and induced abortions by municipality. Exposure was assessed based on nationwide surveys of radiation dose rate from the Chernobyl fallout, from both external and internal exposures. Using these measurements, we estimated the monthly dose rate for each of the 455 Finnish municipalities. On average, the dose rate from Chernobyl fallout reached 50 microSv per month in May 1986--a doubling of the natural background radiation. In the most heavily affected area, 4 times the normal background dose rates were recorded. Given the underlying regional differences in live birth, stillbirth, and abortion rates, we used longitudinal analysis comparing changes over time within municipalities. A temporary decline in the live birth rate had already begun before 1986, with no clear relationship to the level of fallout. A statistically significant increase in spontaneous abortions with dose of radiation was observed. No marked changes in induced abortions or stillbirths were observed. The decrease in the live birth rate is probably not a biological effect of radiation, but more likely related to public concerns of the fallout. The effect on spontaneous abortions should be interpreted with caution, because of potential bias or confounding. Further, there is little support in the epidemiologic literature on effects of very low doses of radiation on pregnancy outcome.
STUK-Radiation and Nuclear Safety Authority, Helsinki, Finland. anssi.auvinen@stuk.fi
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A
Auvinen
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M
Vahteristo
H
H
Arvela
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M
Suomela
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T
Rahola
M
M
Hakama
T
T
Rytömaa
D000022:Abortion, Spontaneous / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D004781:Environmental Exposure / Q000009:adverse effects / Q000032:analysis*; D005260:Female; D005313:Fetal Death / Q000453:epidemiology; D005387:Finland / Q000453:epidemiology; D006801:Humans; D008137:Longitudinal Studies; D011210:Power Plants; D011247:Pregnancy / Q000528:radiation effects*; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011847:Radioactive Fallout / Q000009:adverse effects; D018788:Radioactive Hazard Release; D014455:Ukraine / Q000453:epidemiology
D011847:Radioactive Fallout