[Pathogenic bacteria in the nasal vestivulum of children with acute respiratory tract infection].
The isolation frequency of pathogenic bacteria for acute respiratory infection (ARI) in the pharynx and nasal vestivulum was investigated. Age group-matched children with or without ARI including 109 individuals in each group were examined. Any of the organisms, which are widely regarded as the pathogens causing ARI such as Haemophilus influenzae, Streptococcus pneumoniae, beta-haemolytic Streptococcus, Staphylococcus aureus, and Moraxella catarrhalis, were isolated from 91% of the patient group and from 77% of the healthy group. The isolation frequency of S. pneumoniae in the nasal vestivulum of the patient group was outstanding. The healthy carrier rates of S. pneumoniae in the pharynx and nasal vestivulum were 9% and 8%, respectively. Whereas the isolation frequencies from the patient group were 7% and 28%, respectively. alpha-haemolytic Streptococci except S. pneumoniae revealed different tendency from S. pneumoniae. These organisms were almost always isolated from their pharynx but rarely isolated from the nasal vestivulum. The isolation frequency of H. influenzae from the pharynx of the patient group was 41%, which was slightly higher than 34% in the healthy group, but the difference was statistically not significant. H. influenzae was not isolated from the nasal vestivulum of the healthy group, nevertheless it was isolated from 25% of the patient group. The isolation of H. influenzae from the nasal vestivulum may have some important information about ARI. S. aureus was isolated from the pharynx with higher rate than the nasal vestivulum in both groups, and moreover, the isolation frequency of S. aureus in the healthy group was higher than the patient group. It means that the diagnosis of staphylococcal infection should be made very carefully. Considering the results of this study, it could be said that bacteriologic examination of the specimens from nasal vestivulum is valuable to determine S. pneumoniae and H. influenzae as the etiologic agents of ARI.
Department of Fundamental Nursing, Faculty of Medicine, University of the Ryukyus.
S
S
Kakinohana
H
H
Hamabata
N
N
Higa
N
N
Nakasone
D000208:Acute Disease; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D001936:Moraxella catarrhalis / Q000302:isolation & purification; D009296:Nasal Cavity / Q000382:microbiology*; D012141:Respiratory Tract Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification; D013291:Streptococcus / Q000302:isolation & purification