[Study of the plasma adrenomedullin value in pregnancy induced hypertension patients].
OBJECTIVE
To investigate the relationship between adrenomedullin(ADM) and pregnancy induced hypertension(PIH).


METHODS
The ADM values in the plasma from 12 normal term-pregnant women and 26 women with PIH were determined by specific radioimmunoassay.


RESULTS
(1) The ADM value in the PIH (24.67 +/- 1.27) ng/L increased significantly than that of normal pregnancy (19.16 +/- 1.17) ng/L (P < 0.05). (2) There were significant difference between severe(30.00 +/- 1.17) ng/L moderate (24.80 +/- 0.70) ng/L and mild (19.38 +/- 2.65) ng/L PIH groups (P < 0.001). (3) Significant positive correlation was found between plasma ADM value and mean arterial pressure (r = 0.775, P < 0.001).


CONCLUSIONS
The ADM level is closely associated with PIH and may plan an important role in PIH.
General Navy Hospital, Beijing 100037.
B
B
Lü
A
A
Wang
Y
Y
Fei
D053607:Adrenomedullin; D000328:Adult; D000959:Antihypertensive Agents / Q000097:blood*; D005260:Female; D006801:Humans; D010455:Peptides / Q000097:blood*; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D014665:Vasodilator Agents / Q000097:blood
D000959:Antihypertensive Agents; D010455:Peptides; D014665:Vasodilator Agents; D053607:Adrenomedullin