[A method of evaluating the stationary rate of gene migration (a cartographic approach)].
A method of geographic mapping of the stationary (limiting) gene migration rate has been developed. The method is based on approximation of the empirical distribution of gene frequencies by a theoretical steady-state distribution. The maximum likelihood method and the chi 2 minimization method are used to obtain consistent estimations of the gene migration rate as a parameter of the steady-state distribution. The new method makes it possible to determine the geographical distribution of the ratio between the properties of the population migration structure described by the stepping-stone and island models and to construct a geographical map of chi 2 values. This map approximately reflects the distribution of natural selection pressure on the gene pool if genetic processes are quasisteady.
Evsiukov
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AN
Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 117809 Russia. evsyukov@vigg.ru
Zhukova
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OV
D005787:Gene Frequency; D005788:Gene Pool; D005843:Geography; D006801:Humans; D016013:Likelihood Functions; D012641:Selection, Genetic