Mohs micrographic surgery for the treatment of spindle cell tumors of the skin.
BACKGROUND
Because of the uncommon nature of dermal spindle cell tumors, the effectiveness of various treatment modalities is difficult to assess.


OBJECTIVE
Our purpose was to measure the effectiveness of treating dermatofibrosarcoma protuberans, atypical fibroxanthoma, malignant fibrous histiocytoma, and leiomyosarcoma by means of Mohs micrographic surgery (MMS). In addition, we attempted to determine whether MMS is useful in treating dermal spindle cell tumors when no definitive histopathologic diagnosis can be rendered.


METHODS
In a retrospective chart review, demographic data, tumor data, treatment characteristics, recurrence, and follow-up data were tabulated.


RESULTS
The recurrence rate for dermatofibrosarcoma protuberans treated by MMS was 3.0%, for atypical fibroxanthoma was 6.9%, for malignant fibrous histiocytoma was 43%, and for leiomyosarcoma was 14%. The recurrence rate for spindle cell tumors not otherwise specified was 0%.


CONCLUSIONS
These data establish the effectiveness of MMS in the treatment of dermal spindle cell tumors, including those for which no definitive histopathologic diagnosis can be rendered.
Northwest Medical Center, Tucson, AZ, USA.
M J
MJ
Huether
J A
JA
Zitelli
D G
DG
Brodland
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000601:surgery*