Spontaneous remission of cyclic neutropenia during pregnancy. A case report.
BACKGROUND
Cyclic neutropenia is characterized by regularly recurring episodes of neutropenia. It has been reported that pregnancy often has a mitigating effect on the symptoms. However, there have been no detailed studies on changes in the neutrophil count before, during and after pregnancy.


METHODS
A 24-year-old woman with cyclic neutropenia had a successful pregnancy, during which her symptoms improved spontaneously, with decreased severity. The disease recurred soon after pregnancy, and cyclic neutropenia was inherited by the child.


CONCLUSIONS
Cyclic neutropenia may follow a favorable course during pregnancy, with decreased severity, but postpartum maternal and neonatal complications can occur.
Department of Obstetrics and Gynecology, Shiga University of Medical Sciences, Seta, Ohtsu 520-2192, Japan. hqgyne@belle.shiga-med.ac.jp
T
T
Kimura
K
K
Takakura
T
T
Nakagawa
Y
Y
Yamamoto
N
N
Kita
Y
Y
Noda
D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007958:Leukocyte Count; D009503:Neutropenia / Q000097:blood* / Q000151:congenital; D009504:Neutrophils / Q000166:cytology; D010507:Periodicity; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood*; D012008:Recurrence