Nitrile reduction in the presence of Boc-protected amino groups by catalytic hydrogenation over palladium-activated Raney-nickel.
Welsh School of Pharmacy, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff CF10 3XF, UK.
B
B
Klenke
I H
IH
Gilbert
D000588:Amines / Q000138:chemical synthesis*; D005563:Formic Acid Esters / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D011073:Polyamines / Q000138:chemical synthesis
D000588:Amines; D005563:Formic Acid Esters; D009570:Nitriles; D011073:Polyamines; C000345:t-butyloxycarbonyl group; D010165:Palladium; D009532:Nickel