New eudesmane sesquiterpenes from the root of Lindera strychnifolia.
Strychnistenolide (1) and its acetate 2 were isolated from the root of Lindera strychnifolia, along with a novel rearranged type of secoeudesmane, strychnilactone (3). Their structures were elucidated by extensive analysis of their NMR spectra, including 2D NMR techniques, together with an X-ray analysis for 3. Strychnistenolide exists as a single stereoisomer in CHCl(3), but in pyridine is epimerized.
Kouno
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Faculty of Pharmaceutical Sciences, Nagasaki University, Bunkyo-machi 1-14, Nagasaki 852-8521, Japan. ikouno@net.nagasaki-u.ac.jp
Hirai
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Fukushige
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A
Jiang
Z H
ZH
Tanaka
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T
D002681:China; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D019770:Lauraceae / Q000737:chemistry*; D009281:Naphthalenes / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D045787:Sesquiterpenes, Eudesmane
D004365:Drugs, Chinese Herbal; D009281:Naphthalenes; D010936:Plant Extracts; D012717:Sesquiterpenes; D045787:Sesquiterpenes, Eudesmane; C429209:strychnilactone; C429208:strychnistenolide; C015872:eudesmane