Characterization of human FSD1, a novel brain specific gene on chromosome 19 with paralogy to 9q31.
We have characterized a novel human gene, FSD1, on chromosome 19. FSD1 has a BBC, FN3 and SPRY domain, it is distantly related to the midline 1 gene and is expressed only in the brain. We have established its exon-intron structure and we have identified the corresponding orthologous genes in other species. In addition, the identification of FSD1 has led us to identify a homologous counterpart sequence on chromosome 9.
Medical and Molecular Genetics Center, Institut de Recerca Oncològica, Departament de Genètica Molecular, Hospital Duran i Reynals, Av. Gran Via s/n, km 2.7, L'Hospitalet de Llobregat, 08907, Barcelona, Spain
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Carim-Todd
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Escarceller
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Estivill
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Sumoy
D017398:Alternative Splicing; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001921:Brain / Q000378:metabolism / Q000473:pathology; D002888:Chromosomes, Human, Pair 19; D018076:DNA, Complementary; D005091:Exons; D005353:Fibronectins / Q000235:genetics; D020869:Gene Expression Profiling; D006801:Humans; D007438:Introns; D051379:Mice; D008969:Molecular Sequence Data; D009419:Nerve Tissue Proteins / Q000235:genetics* / Q000378:metabolism; D011506:Proteins / Q000235:genetics* / Q000378:metabolism; D017386:Sequence Homology, Amino Acid
D018076:DNA, Complementary; C429034:FSD1 protein, human; D005353:Fibronectins; C486079:Fsd1 protein, mouse; D009419:Nerve Tissue Proteins; D011506:Proteins