Efficacy of standard ten millicurie dose of radio-iodine in management of autonomously functioning toxic thyroid nodules.
Therapeutic effect of radio-iodine treatment on thyroid patients with autonomously functioning toxic thyroid nodule was evaluated. Fifty one patients were given a standard dose of 10 mci of radioiodine (I-131) and were followed up for 2-3 years. The failure rate (relapse after 10 mci of radioiodine) of this regime was 10%. It was found that the nodules less than or equal to 3 cms. in size were completely cured after a dose of 10 mic. of radio-iodine therapy, over a follow up period of next 6 months. Patients having nodules larger than 3 cms. relapsed after first dose of 10 mci of radio-iodine, but were cured completely after the second dose of 10 mci of radio-iodine therapy. Tri-iodothyronine (T3) and thyroxine (T4) values were both found to be high before giving treatment in all the cases. Only one case developed hypothyroidism after radioiodine therapy.
Sharma
R
R
Inst. of Nuclear Medicine and Allied Sciences, New Delhi.
Bhatnagar
A
A
Mondal
A
A
Kashyap
R
R
Khanna
C M
CM
D005260:Female; D005500:Follow-Up Studies; D006044:Goiter, Nodular / Q000150:complications / Q000532:radiotherapy*; D006801:Humans; D006980:Hyperthyroidism / Q000209:etiology / Q000532:radiotherapy*; D007457:Iodine Radioisotopes / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D016896:Treatment Outcome
D007457:Iodine Radioisotopes