Stereoselective reactions. XXXIIII. Design and synthesis of chiral bidentate amines having a bulky group on the chiral carbon.
Based on the solution structures of chiral bidentate lithium amides ((R)-3a,b) having a phenyl group on the chiral carbon, chiral bidentate amines ((R)-5a,b-8a,b and (S)-9a,b) having a bulkier group instead of a phenyl group on the chiral carbon were designed and synthesized.
College of Pharmacy, Nihon University, Chiba, Japan.
M
M
Toriyama
A N
AN
Tokutake
K
K
Koga
D000577:Amides / Q000737:chemistry*; D018020:Lithium Compounds / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008968:Molecular Conformation; D013237:Stereoisomerism
D000577:Amides; D018020:Lithium Compounds