Psychiatric comorbidity is related to headache induced by chronic substance use in migraineurs.
Headache centers have to deal with patients suffering from headache induced by chronic substance use which is a well-recognized complication of migraine treatment. The objective of this study was to compare psychiatric comorbidity between migraineurs with and without chronic substance use: 34 migrainous inpatients with chronic substance use were compared with 34 sex-matched noncomplicated migraineurs in a case-control study. The results showed a significantly higher prevalence of major depressive disorder, panic disorder, and social phobia in the patients with a history of chronic substance use. Consistently, anxious and depressive dimensions were significantly higher in these patients. Therefore, psychiatric morbidity may be linked to chronic substance use in migraineurs. This stresses the importance of psychiatric assessment and the need for appropriate treatment in such patients.
IPSO, Hôpital Charles Perrens, 121 rue de la Bechade, 33076 Bordeaux, France.
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Radat
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Sakh
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Lutz
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el Amrani
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Ferreri
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Bousser
D000328:Adult; D000700:Analgesics / Q000008:administration & dosage / Q000009:adverse effects; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D001008:Anxiety Disorders / Q000175:diagnosis / Q000523:psychology*; D016022:Case-Control Studies; D015897:Comorbidity; D003866:Depressive Disorder / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D020773:Headache Disorders / Q000139:chemically induced* / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy* / Q000523:psychology; D012307:Risk Factors; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis / Q000523:psychology*; D019966:Substance-Related Disorders / Q000523:psychology*
D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal