Clear cell syringofibroadenoma (of Mascaro) of the nail.
Eccrine syringofibroadenoma (ESFA) is a rare disorder. We report the first case of ESFA of the nail apparatus, which presented as a yellow longitudinal onycholytic band of the left fourth finger over an intermittently painful subungual filamentous tumour. Histological examination showed features of ESFA with a digitate pattern of papillomatosis due to the specialized physiological longitudinal arrangement of the ridges in the nail bed. In addition, we describe a new feature of colloidal iron-positive clear cells. In our case, the presence of two types of cells with a central ductal differentiation and a significant amount of mucopolysaccharides in clear cells could suggest differentiation towards both the ductal and the secretory portion of the eccrine gland.
Fouilloux
B
B
Département d'Onychologie, Service de Dermatologie, CHU St-Etienne, France Service d'Anatomo-Pathologie, Hôpital Pasteur, Nice, France.
Perrin
C
C
Dutoit
M
M
Cambazard
F
F
D000368:Aged; D005260:Female; D018226:Fibroadenoma / Q000473:pathology*; D006801:Humans; D009260:Nail Diseases / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000473:pathology*; D018252:Syringoma / Q000473:pathology*