Two new diterpenoid alkaloids, beiwusines A and B, from Aconitum kusnezoffii.
Two new atisine-type diterpenoid alkaloids, beiwusine A (1) and B (2), have been isolated from the roots of Aconitum kusnezoffii Reichb. Their structures were established on the basis of spectroscopic data. Beiwusines A and B are the first examples of atisine-type diterpenoid alkaloids having a hydroxyl group at C-1. In addition, one known diterpenoid alkaloid spiramine H (3) has been isolated.
Department of Chemistry of Medicinal Natural Products, School of Pharmacy, West China University of Medical Sciences, Chengdu 610041, China.
Z B
ZB
Li
F P
FP
Wang
D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D013057:Spectrum Analysis
D004224:Diterpenes; C423946:beiwusine A; C423947:beiwusine B