The process of epileptogenesis: a pathophysiological approach.
Several recent advances have contributed to our understanding of the processes associated with mesial temporal lobe epilepsy in humans and in experimental animal models. Common pathological features between the human condition and the animal models may indicate a fundamental involvement of the given pathology in the process of epileptogenesis.
Dalby
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Department of Neurology, UCLA School of Medicine, 710 Westwood Plaza, Los Angeles, California 90095-1769, USA.
Mody
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D000818:Animals; D004195:Disease Models, Animal; D004833:Epilepsy, Temporal Lobe / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology*; D018698:Glutamic Acid / Q000378:metabolism; D006624:Hippocampus / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D007395:Interneurons / Q000378:metabolism / Q000473:pathology; D019599:Mossy Fibers, Hippocampal / Q000378:metabolism / Q000473:pathology; D009433:Neural Inhibition / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid