A clinical investigation on garlicin injectio for treatment of unstable angina pectoris and its actions on plasma endothelin and blood sugar levels.
To investigate the therapeutic effects and mechanisms of garlicin for treatment of unstable angina pectoris (UAP), garlicin injectio was intravenously dripped 60 mg/day in 34 cases for 10 days. Nitroglycerine was used in 21 cases of the control group. The results showed that the total effective rates in improving symptoms and electrocardiogram after garlicin treatment were respectively 82% and 62%, and that the plasma endothelin and blood sugar levels were markedly lowered in cases with hyperglycemia.
TCM Department of Cardio-renal Diseases, Sino-Japanese Friendship Hospital, Beijing 100029.
G
G
Li
Z
Z
Shi
H
H
Jia
J
J
Ju
X
X
Wang
Z
Z
Xia
L
L
Qin
C
C
Ge
Y
Y
Xu
L
L
Cheng
P
P
Chen
G
G
Yuan
D000368:Aged; D000498:Allyl Compounds / Q000627:therapeutic use*; D000789:Angina, Unstable / Q000097:blood / Q000188:drug therapy*; D001786:Blood Glucose / Q000187:drug effects*; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D004220:Disulfides / Q000627:therapeutic use*; D016232:Endothelins / Q000097:blood*; D005260:Female; D005737:Garlic; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use; D010946:Plants, Medicinal
D000498:Allyl Compounds; D001786:Blood Glucose; D002317:Cardiovascular Agents; D004220:Disulfides; D016232:Endothelins; D007004:Hypoglycemic Agents; D010936:Plant Extracts; C028009:diallyl disulfide