Left-right determination.
Recent advances have given us new insights into the molecular basis of organ position. A gene cascade that determines left-right positioning of organ primordia has emerged. In here we present the current knowledge of the molecular determinants of organ positioning during vertebrate embryogenesis.
Ruiz-Lozano
P
P
Department of Medicine, University of California, San Diego, La Jolla, CA 92093-0613, USA. plozano@ucsd.edu
Ryan
A K
AK
Izpisua-Belmonte
J C
JC
D000015:Abnormalities, Multiple / Q000196:embryology / Q000235:genetics; D000818:Animals; D005314:Embryonic and Fetal Development / Q000502:physiology*; D007839:Functional Laterality / Q000235:genetics / Q000502:physiology; D006801:Humans; D015398:Signal Transduction / Q000502:physiology; D012857:Situs Inversus / Q000196:embryology / Q000235:genetics