The in vitro effects of ketamine at large concentrations can be attributed to a nonspecific cytostatic effect.
Lewis
E
E
Department of Nephrology, Soroka University Medical Center, Ben-Gurion University of the Negev, Faculty of Health Sciences, Beer-Sheva, Israel.
Rogachev
B
B
Shaked
G
G
Douvdevani
A
A
D000778:Anesthetics, Dissociative / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D004847:Epithelial Cells / Q000187:drug effects / Q000378:metabolism; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology*; D006801:Humans; D015850:Interleukin-6 / Q000096:biosynthesis; D007649:Ketamine / Q000008:administration & dosage / Q000494:pharmacology*; D008070:Lipopolysaccharides / Q000494:pharmacology; D051379:Mice; D009000:Monocytes / Q000187:drug effects
D000778:Anesthetics, Dissociative; D018691:Excitatory Amino Acid Antagonists; D015850:Interleukin-6; D008070:Lipopolysaccharides; D007649:Ketamine