Spectrum and age-related incidence of spontaneous tumours in a colony of Han:AURA hamsters.
One-hundred-and-forty-four male and 184 female untreated Syrian golden hamsters (strain Han:AURA) were kept for life under standard laboratory conditions. They were examined with regard to spontaneously occurring tumours in relation to their survival periods. The mean survival rate of the males was 106 +/- 26 weeks and that of the females 97 +/- 20 weeks. Tumours were found in 71% of males and 67% of females. Adenomas and carcinomas of the adrenal glands were the most frequently observed tumours in both sexes (male: 66%; female: 38%) and in the early stages of life. Malignant lymphoma (8%), adenomas and carcinomas of pancreatic islet-cells (8%) and papillomatous benign and malignant squamous cell tumours of the forestomach (7%) showed relatively high incidences in males, whilst in females, leiomyoma (10%) and endometrial adenocarcinoma (7%) of the uterus and adenomas and carcinomas in the pars distalis of the pituitary gland (9%) occurred frequently.
Institute of Experimental Pathology, Hannover Medical School, Germany.
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Kamino
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Tillmann
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Mohr
D000818:Animals; D006224:Cricetinae; D005260:Female; D008017:Life Expectancy; D008136:Longevity; D008297:Male; D008647:Mesocricetus; D009369:Neoplasms / Q000401:mortality / Q000473:pathology / Q000662:veterinary*; D012376:Rodent Diseases / Q000453:epidemiology*; D015996:Survival Rate