The synthesis of beta-peptides containing guanidino groups.
The synthesis of the beta-peptide 1 by the postsynthetic modification of the corresponding amino-containing peptide 3 is described. The potential of 1 to act as a template for the ligation of complementary negatively-charged peptides is discussed.
The Salk Institute for Biological Studies, San Diego, CA 92186, USA.
K
K
Wen
H
H
Han
T Z
TZ
Hoffman
K D
KD
Janda
L E
LE
Orgel
D000596:Amino Acids / Q000737:chemistry*; D002942:Circular Dichroism; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D017433:Protein Structure, Secondary
D000596:Amino Acids; D010455:Peptides