Proteins of Mycobacterium bovis BCG induced in the Wayne dormancy model.
Oxygen starvation triggers the shiftdown of the obligate aerobe Mycobacterium bovis BCG to a state of dormancy. Two-dimensional electrophoresis showed a drastic up-regulation of the alpha-crystallin homolog, the putative response regulator Rv3133c, and the two conserved hypothetical proteins Rv2623 and Rv2626c in dormant bacilli.
Mycobacterium Laboratory, Institute of Molecular and Cell Biology, Singapore 117609, Republic of Singapore.
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D000332:Aerobiosis; D000693:Anaerobiosis; D001426:Bacterial Proteins / Q000096:biosynthesis*; D003459:Crystallins / Q000096:biosynthesis; D003470:Culture Media; D015180:Electrophoresis, Gel, Two-Dimensional; D008954:Models, Biological; D009163:Mycobacterium bovis / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D014158:Transcription, Genetic; D015854:Up-Regulation
D001426:Bacterial Proteins; D003459:Crystallins; D003470:Culture Media