[Observation on large doses of urokinase in treatment of sudden deafness].
From September 1992 to July 1997 56 cases (59 ears) of sudden deafness were treated with urokinase 20,000 unit a day for ten days. At the same time also using Papaverine hydrochloride, ATP and CoA. The effective rate of treatment was 86.44%. But for the control group of 48 cases treated with only Papavrine hydrochloride, ATP and CoA, the effective rate of treatment was 63.32%. There was significant difference between the two groups (P < 0.01). In addition, urokinase is safe and reliable in treating sudden deafness and has not be found any evident side-effect.
Cheng
Z
Z
Department of Otolaryngology, Lanlian Hospital, Lanzhou 730060.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D003639:Hearing Loss, Sudden / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000627:therapeutic use; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use
D014665:Vasodilator Agents; D010208:Papaverine; D014568:Urokinase-Type Plasminogen Activator