[The study of ultrastructure of atrial natriuretic peptides immunoreactive in cochlear of guinea pigs].
To further explore ultrastructure of atrial natriuretic peptides immunoreactive (ANP-IR) products in cochlear of guinea pig, and secretory type, ultrastructure of ANP-IR products of stria vascularis were studied with immunoelectronic microscopy. The result indicated: ANP-IR granules were seen in the cytoplasm, more obviously at the ends of the nucleus. There were two types of granule: storage and secretory granule. The study suggests that ANPs were secreted by rupture of restriction membrane, not by exocytosis secretion.
Nanfang Hospital, First Military Medical University, Guangzhou 510515.
H
H
Chen
J
J
Wang
D000818:Animals; D009320:Atrial Natriuretic Factor / Q000032:analysis* / Q000648:ultrastructure*; D003051:Cochlea / Q000737:chemistry / Q000648:ultrastructure*; D006168:Guinea Pigs; D016253:Microscopy, Immunoelectron; D013316:Stria Vascularis / Q000737:chemistry / Q000648:ultrastructure
D009320:Atrial Natriuretic Factor