Targeted inhibition of the small GTPase protects against ischemia/reperfusion liver injury in mice.
Department of Surgical Research, National Children's Hospital, Tokyo, Japan.
M
M
Ozaki
S
S
Deshpande
P
P
Angkeow
J
J
Bellan
C J
CJ
Lowenstein
M C
MC
Dinauer
P
P
Goldschmidt-Clermont
S
S
Suzuki
K
K
Irani
D000256:Adenoviridae / Q000235:genetics; D000818:Animals; D017209:Apoptosis; D004790:Enzyme Induction; D015227:Lipid Peroxidation; D008099:Liver / Q000098:blood supply* / Q000201:enzymology / Q000473:pathology; D051379:Mice; D008810:Mice, Inbred C57BL; D016328:NF-kappa B / Q000378:metabolism; D009336:Necrosis; D017382:Reactive Oxygen Species / Q000378:metabolism*; D015427:Reperfusion Injury / Q000201:enzymology / Q000473:pathology / Q000517:prevention & control*; D014162:Transfection; D020830:rac1 GTP-Binding Protein / Q000037:antagonists & inhibitors* / Q000235:genetics
D016328:NF-kappa B; D017382:Reactive Oxygen Species; D020830:rac1 GTP-Binding Protein