Rapamycin reduces expression of fibrosis-associated genes in an experimental model of renal ischaemia reperfusion injury.
Jain
S
S
Department of Transplant Surgery, Leicester General Hospital, Leicester, UK.
Bicknell
G R
GR
Whiting
P H
PH
Nicholson
M L
ML
D000818:Animals; D016572:Cyclosporine / Q000494:pharmacology; D005355:Fibrosis / Q000235:genetics / Q000517:prevention & control; D015870:Gene Expression / Q000187:drug effects*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D016030:Kidney Transplantation; D008297:Male; D008666:Metalloendopeptidases / Q000378:metabolism; D023421:Models, Animal; D051381:Rats; D017208:Rats, Wistar; D015427:Reperfusion Injury / Q000150:complications*; D020123:Sirolimus / Q000494:pharmacology*; D016212:Transforming Growth Factor beta / Q000378:metabolism
D007166:Immunosuppressive Agents; D016212:Transforming Growth Factor beta; D016572:Cyclosporine; D008666:Metalloendopeptidases; D020123:Sirolimus