Seeking a vaccine against Coccidioides immitis and serologic studies: expectations and realities.
The studies reported in this review indicate that, whereas the expectations from the molecular approach help to excite and enlighten us, the realities suggest that even some less modern approaches may provide the necessary practical solutions to problems of serology and vaccination against coccidioidomycosis. Concurrent conduct of the two approaches should maximize the chances for success.
School of Medicine, University of California, Davis, California 95616, USA.
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Pappagianis
D000818:Animals; D003045:Coccidioides / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity; D003047:Coccidioidomycosis / Q000097:blood / Q000276:immunology / Q000517:prevention & control*; D003168:Complement Fixation Tests; D005657:Fungal Vaccines / Q000008:administration & dosage; D006801:Humans; D007110:Immunity, Active; D011233:Precipitin Tests; D014611:Vaccination
D005657:Fungal Vaccines