Molecular recognition of carbohydrates by artificial receptors: systematic studies towards recognition motifs for carbohydrates.
The synthesis and binding properties for carbohydrates of several artificial, acyclic receptors containing two or three heterocyclic recognition units covalently attached to a phenyl spacer is described. These host molecules having uncharged hydrogen-bonding sites were used in a systematic study towards the evaluation of recognition motifs for carbohydrates. A novel effective, acyclic hydrogen-bonding receptor possessing naphthyridine-amide moieties as heterocyclic recognition units has been developed.
Institut für Organische Chemie der Universität Essen, Germany. monika.mazik@oc1.orgchem.uni-essen.de
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