A benzofuran glycoside and an acetylenic acid from the fungus Laetiporus sulphureus var. miniatus.
A new benzofuran glycoside, masutakeside I (1) and a new C10 acetylenic acid, masutakic acid A (2) were isolated from the fruiting bodies of the fungus Laetiporus sulphureus var. miniatus. Their structures were established by spectroscopic and chemical methods. The known compounds 3-6 were also obtained and identified as egonol, demethoxyegonol, egonol glucoside and egonol gentiobioside. Some of these compounds exhibited cytotoxicity against Kato III cells.
Yoshikawa
K
K
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan. yosikawa@ph.bunri-u.ac.jp
Bando
S
S
Arihara
S
S
Matsumura
E
E
Katayama
S
S
D000480:Alkynes; D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology*; D001572:Benzofurans / Q000737:chemistry* / Q000302:isolation & purification; D004354:Drug Screening Assays, Antitumor; D005231:Fatty Acids, Unsaturated / Q000737:chemistry* / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D011124:Polyporaceae / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet; D014407:Tumor Cells, Cultured
D000480:Alkynes; D000970:Antineoplastic Agents; D001572:Benzofurans; D005231:Fatty Acids, Unsaturated; D006027:Glycosides; C430809:masutakeside I; C430810:masutakic acid A; C031203:2-hexadecynoic acid