Two siblings with chronic myelogenous leukemia.
In the present study we report the occurrence of Chronic Myelogenous Leukemia in two siblings (brother and sister) 47 and 62 years old respectively. These two cases raised the question of a possible genetic prodiathesis or a possible trasmission (environmental factor) cause.
Kapsali
E
E
Dept. of Internal Medicine, University Hospital of Ioannina, Medical School, Greece.
Tsiara
S
S
Christou
L
L
Panteli
A
A
Bourantas
K L
KL
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D006918:Hydroxyurea / Q000008:administration & dosage; D016898:Interferon-alpha / Q000008:administration & dosage; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009679:Nuclear Family; D010677:Philadelphia Chromosome; D016133:Polymerase Chain Reaction; D016896:Treatment Outcome
D016898:Interferon-alpha; D006918:Hydroxyurea