Maelstrom is required to position the MTOC in stage 2-6 Drosophila oocytes.
The factors that determine intracellular polarity are largely unknown. In Drosophila oocytes one of the earliest polar events is the positioning of the microtubule-organizing center (MTOC). Here we present data that are consistent with the hypothesis that maelstrom is required for posterior positioning of the MTOC.
Clegg
N J
NJ
Department of Biochemistry, University of Washington, Seattle 98195, USA.
Findley
S D
SD
Mahowald
A P
AP
Ruohola-Baker
H
H
D000818:Animals; D016764:Cell Polarity; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000502:physiology*; D017930:Genes, Reporter; D019476:Insect Proteins / Q000235:genetics / Q000378:metabolism*; D016547:Kinesins; D018613:Microscopy, Confocal; D008868:Microtubule Proteins / Q000378:metabolism; D022101:Microtubule-Organizing Center / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism; D009865:Oocytes / Q000254:growth & development / Q000502:physiology* / Q000648:ultrastructure; D011993:Recombinant Fusion Proteins / Q000378:metabolism
D029721:Drosophila Proteins; D019476:Insect Proteins; D008868:Microtubule Proteins; D011993:Recombinant Fusion Proteins; C109767:mael protein, Drosophila; C080298:Nod protein, Drosophila; D016547:Kinesins