Role of pinaverium bromide in south Indian patients with irritable bowel syndrome.
The effect of pinaverium bromide in controlling gastrointestinal symptoms in 61 patients with irritable bowel syndrome was studied, as an open trial. Individually, there was significant relief in abdominal discomfort/pain as well as in bowel symptoms in most of the patients. Abdominal pain was reduced in 49%, stool consistency improved in 74%, straining and urgency decreased in 71% and mucus decreased in 64%. Tolerance to the drug administered was good and side-effects reported were few.
Department of Digestive Health and Disease, Government Peripheral Hospital,  Kilpauk Medical College and Hospital), Chennai, India.
V
V
Jayanthi
S
S
Malathi
B
B
Ramathilakam
N
N
Dinakaran
V
V
Balasubramanian
S
S
Mathew
D000328:Adult; D000368:Aged; D003109:Colonic Diseases, Functional / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D009025:Morpholines / Q000008:administration & dosage*; D010276:Parasympatholytics / Q000008:administration & dosage*; D011336:Probability; D016896:Treatment Outcome
D009025:Morpholines; D010276:Parasympatholytics; C013199:pinaverium