Optimal management of dyslipidemia in women and men.
Relatively few studies have examined the clinical effectiveness of cholesterol-lowering drugs in women as compared with men. Most clinical trials do indicate that cholesterol lowering reduces clinical events equally effectively in both genders. However, high-density lipoprotein cholesterol and triglyceride levels may have more prognostic significance in women. The recent finding of a higher risk of death in younger women as compared with younger men who sustain a heart attack, combined with the high proportion of morbidity and mortality due to CHD in older women, emphasizes the need for a better understanding of heart disease in women. This review explores the similarities and differences between women and men regarding the management of dyslipidemia.
School of Nursing and School of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
M R
MR
Haymart
J
J
Allen
R S
RS
Blumenthal
D000368:Aged; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D008019:Life Style; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D012727:Sex Characteristics; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology; D016387:Women's Health