A benzofuran glycoside and an acetylenic acid from the fungus Laetiporus sulphureus var. miniatus.
A new benzofuran glycoside, masutakeside I (1) and a new C10 acetylenic acid, masutakic acid A (2) were isolated from the fruiting bodies of the fungus Laetiporus sulphureus var. miniatus. Their structures were established by spectroscopic and chemical methods. The known compounds 3-6 were also obtained and identified as egonol, demethoxyegonol, egonol glucoside and egonol gentiobioside. Some of these compounds exhibited cytotoxicity against Kato III cells.
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan. yosikawa@ph.bunri-u.ac.jp
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Yoshikawa
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Bando
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Arihara
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Matsumura
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Katayama
D000480:Alkynes; D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology*; D001572:Benzofurans / Q000737:chemistry* / Q000302:isolation & purification; D004354:Drug Screening Assays, Antitumor; D005231:Fatty Acids, Unsaturated / Q000737:chemistry* / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D011124:Polyporaceae / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet; D014407:Tumor Cells, Cultured
D000480:Alkynes; D000970:Antineoplastic Agents; D001572:Benzofurans; D005231:Fatty Acids, Unsaturated; D006027:Glycosides; C430809:masutakeside I; C430810:masutakic acid A; C031203:2-hexadecynoic acid