[Pulmonary hyalinising granuloma: report of 2 original cases with cervicofacial and orbital involvement].
BACKGROUND
Pulmonary hyalinizing granuloma is a rare fibrosing nodular disease of the lung characterized by its histological appearance, which includes at the center of the lesion a dense network of concentric hyalinized collagen lamella surrounded by perivascular lymphoplasmacytic infiltrate that rarefies in the center of the nodule.


METHODS
We report two new cases: the first with laryngeal (endoluminal tumor-like), orbital (subeyelid nodule) and mesenteric (9 x 6 cm mass) location of hyalinizing granuloma; the second with cervical, facial (trismus), orbital (pseudotumor) and limb (ankylosing elbow) fibrosis.


CONCLUSIONS
The extrapulmonary diffusion of the disease is extremely rare. In one of the cases, with corticosteroids and after a follow-up of 12 months, the pulmonary tumors vanished but the fibrosis resolved only partially.
Laraki
R
R
Service de médecine interne, hôpital de la Pitié-Salpêtrière, 83, boulevard de l'Hôpital, 75651 Paris, France.
Wechsler
B
B
Bourgeon
B
B
Wechsler
J
J
Charlotte
F
F
Piette
J C
JC
D000328:Adult; D005145:Face; D005260:Female; D006099:Granuloma / Q000150:complications*; D006801:Humans; D006818:Hyalin; D007818:Laryngeal Diseases / Q000209:etiology*; D008171:Lung Diseases / Q000150:complications*; D008643:Mesentery; D009916:Orbital Diseases / Q000209:etiology*