[Clinical significance of serum anti-mycobacterium tuberculosis antibody in diagnosis of tuberculosis].
OBJECTIVE
To evaluate the significance of measuring serum antilipoarabinomannan IgG (LAM-IgG), an anti-Mycobacterium tuberculosis antibody, in diagnosis of tuberculosis.


METHODS
Sensitivity and specificity of the antibody in diagnosis of tuberculosis were detected. Results of the antibody detection, sputum smear and PPD examination were compared, and the relationship between the level of the antibody and the situation of the disease was also observed.


RESULTS
The sensitivity of the antibody in diagnosis of tuberculosis was found to be 71.9%, while the specificity 91.9%. The consistent rates of the antibody with sputum smear and PPD test were 80.2% and 61.6% respectively. The level of the antibody was related with the situation of the disease.


CONCLUSIONS
Detection of the antibody is helpful for diagnosing tuberculosis and can be used to evaluate the prognosis of the disease.
Department of Respiratory Medicine, Beijing Tong Ren Hospital, Capital Medical University, Beijing 100730.
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Q
Lu
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Y
Dong
D000293:Adolescent; D000328:Adult; D000368:Aged; D000907:Antibodies, Bacterial / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000276:immunology / Q000302:isolation & purification*; D012680:Sensitivity and Specificity; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000382:microbiology
D000907:Antibodies, Bacterial