Neutralisation of lethality, myotoxicity and toxic enzymes of Naja kaouthia venom by Mimosa pudica root extracts.
Aqueous and alcoholic extracts of dried roots of Mimosa pudica were tested for their inhibitory activity on lethality, myotoxicity and toxic enzymes of Naja kaouthia venom. The aqueous extract, particularly the normal water extract, displayed a significant inhibitory effect on the lethality, myotoxicity and tested enzyme activities of venom compared with alcoholic extracts. The present finding suggests that aqueous extracts of M. pudica root possess compound(s), which inhibit the activity of cobra venom.
Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur 784 028, India.
M
M
Mahanta
A K
AK
Mukherjee
D000818:Animals; D003402:Creatine Kinase / Q000378:metabolism; D004546:Elapid Venoms / Q000201:enzymology*; D017815:Elapidae; D007928:Lethal Dose 50; D051379:Mice; D010741:Phospholipases A / Q000037:antagonists & inhibitors* / Q000633:toxicity; D010936:Plant Extracts / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry*; D019685:Rosales / Q000737:chemistry*
D004546:Elapid Venoms; D010936:Plant Extracts; D003402:Creatine Kinase; D010741:Phospholipases A