[Detection of 1,4-benzodiazepine derivatives in liver tissues by immunochemical methods].
The possibility of using immunochemical methods in general forensic chemical analysis of cadaveric material for narcotics is demonstrated. Conditions of isolation of 1,4-benzodiasepines from tissues and analysis of the resultant tissue extracts by polarization fluoroimmunoassay (PFIA) and solid-phase enzyme immunoassay are described. Time course of concentrations in tissue extracts stored for a long time has been studied by PFIA. Characteristics of Benzodiazepines Serum kits (Abbott) for PFIA of liver extracts are determined.
S B
SB
Lisovskaia
A V
AV
Smirnov
B N
BN
Izotov
A A
AA
Burkin
D001569:Benzodiazepines / Q000032:analysis*; D016231:Fluorescence Polarization Immunoassay; D005554:Forensic Medicine; D006801:Humans; D008099:Liver / Q000737:chemistry*
D001569:Benzodiazepines