[Tubercular granulomas of the liver in a Somalian patient notwithstanding a chronic hepatitis C].
A 44-year-old male Somalian immigrant was admitted to hospital for evaluation of upper abdominal pain and painful joints (neck and shoulders). Chronic active hepatitis caused by hepatitis C virus was diagnosed. Further examination was instituted because of the simultaneous finding of granulomas in a liver biopsy. In hepatitis C liver granulomas may be found. Infection by Mycobacterium tuberculosis was established, however, after extensive investigation. Treatment was started with tuberculostatic drugs, after which the complaints of the patient disappeared, liver enzyme levels decreased and granulomas in the liver disappeared. No side effects of the tuberculostatic treatment were seen on the course of the hepatitis C.
Afd. Medische Microbiologie, Reinier de Graaf Gasthuis, Reinier de Graafweg 3-11, 2625 AD Delft.
R W
RW
Vreede
C J
CJ
Bolwerk
F
F
Eulderink
D J
DJ
Bac
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D001706:Biopsy; D003937:Diagnosis, Differential; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D012998:Somalia / Q000208:ethnology; D016896:Treatment Outcome; D014375:Tuberculoma / Q000209:etiology / Q000382:microbiology*; D014386:Tuberculosis, Hepatic / Q000175:diagnosis / Q000382:microbiology*
D000995:Antitubercular Agents