Making the most of cholesterol-lowering margarines.
Used as a substitute for normal dietary intake of saturated fatty acids, margarines containing plant sterols can cause a modest reduction in serum total cholesterol and low-density lipoprotein cholesterol levels. They have been shown effective in patients with mild hypercholesterolemia, but they are also useful in the general population.
Preventive Cardiology and Rehabilitation Program, Cleveland Clinic Heart Center, Cleveland Clinic Foundation, OH 44195, USA. averyj@ccf.org
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D000924:Anticholesteremic Agents / Q000627:therapeutic use; D002784:Cholesterol / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood; D003327:Coronary Disease / Q000150:complications / Q000178:diet therapy; D003365:Costs and Cost Analysis; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications / Q000178:diet therapy / Q000188:drug therapy; D006949:Hyperlipidemias / Q000150:complications / Q000178:diet therapy / Q000188:drug therapy; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008383:Margarine / Q000191:economics; D010840:Phytosterols; D016032:Randomized Controlled Trials as Topic; D019821:Simvastatin / Q000627:therapeutic use; D012855:Sitosterols; D013997:Time Factors
D000924:Anticholesteremic Agents; D008078:Cholesterol, LDL; D000960:Hypolipidemic Agents; D010840:Phytosterols; D012855:Sitosterols; C407042:plant stanol ester; D008383:Margarine; D002784:Cholesterol; D019821:Simvastatin