Nucleotide sequence of genome segment 5 from Bombyx mori cypovirus 1.
The complete nucleotide sequences of the double-stranded RNA genome segments 5 (S5) from Bombyx mori cypovirus 1 (BmCPV-1) strains I and H were determined. The segments consisted of 2,852 nucleotides encoding putative proteins of 881 amino acids with molecular masses of approximately 101 kDa (p101). A homology search showed that p101 has high similarity (93%) to foot-and-mouth disease virus (FMDV) 2A protease (2Apro) at amino acid position 219 to 235. These findings suggest the possibility that p101 encoded by BmCPV-1 S5 might be cleaved into two non-structural proteins by post-translational autocleavage involving a 2Apro-like protease.
Venture Laboratory, Kyoto Institute of Technology, Kyoto, Japan.
K
K
Hagiwara
J
J
Kobayashi
M
M
Tomita
T
T
Yoshimura
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D012831:Bombyx / Q000821:virology*; D003001:Cloning, Molecular; D016679:Genome, Viral; D008969:Molecular Sequence Data; D008970:Molecular Weight; D012087:Reoviridae / Q000737:chemistry / Q000235:genetics*; D017386:Sequence Homology, Amino Acid; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics*
D014764:Viral Proteins