A correlation between renal morphology and renal circulation in pediatric nephrotic syndrome.
A morphometric analysis of the renal biopsy specimens and intrarenal hemodynamic study were performed in 37 pediatric patients with idiopathic nephrotic syndrome. The study indicated an inverse correlation between intrarenal hemodynamics (renal plasma flow and peritubular capillary flow) and a relative area of renal cortical interstitium. In respect to the glomerular study, the incidence of glomerulosclerosis increased as the renal perfusion decreased, however, the correlation did not reach a statistical significance.
Department of Pathology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
S
S
Yenrudi
A
A
Laohapaibul
W
W
Kittidiwit
S
S
Suteparuk
N
N
Futrakul
D001706:Biopsy; D002648:Child; D005919:Glomerular Filtration Rate; D005923:Glomerulosclerosis, Focal Segmental / Q000473:pathology; D006801:Humans; D007457:Iodine Radioisotopes; D007465:Iodohippuric Acid; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology*; D007678:Kidney Glomerulus / Q000473:pathology; D009404:Nephrotic Syndrome / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012079:Renal Circulation; D016284:Technetium Tc 99m Pentetate
D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D007465:Iodohippuric Acid; D016284:Technetium Tc 99m Pentetate