Evaluation of microalb immunoturbidimetric test for albuminuria screening.
Microalb, an immunoturbidimetric test for screening urinary albumin levels was evaluated for its potential as a screening test for microalbuminuria in diabetic patients. It was compared with the current standard, the radioimmunoassay (RIA). The results showed that the test lacks sensitivity while its specificity was acceptable. Therefore, it can not replace the RIA as the screening method. This study also showed that the first early morning urine could be used if a 24- hour collection was not possible, as its albumin content fairly correlated (r = 0.78) with the 24-hour urine collection of the diabetic patients.
Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
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Ujjin
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Wiwanitkit
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Srijindaratana
D000328:Adult; D000419:Albuminuria / Q000175:diagnosis*; D003920:Diabetes Mellitus / Q000652:urine*; D003928:Diabetic Nephropathies / Q000652:urine; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry / Q000379:methods*; D011237:Predictive Value of Tests; D011379:Prognosis; D011863:Radioimmunoassay; D011933:Reagent Kits, Diagnostic; D011934:Reagent Strips; D012680:Sensitivity and Specificity; D013997:Time Factors
D011933:Reagent Kits, Diagnostic; D011934:Reagent Strips