Role of CTLA 4-Ig on induction of unresponsiveness to multiple minor alloantigens.
LPS blasts inhibited graft rejection in multiple minor incompatible strain combinations but not in presensitized animals or in major histoincompatible combinations.
Gorczynski
R M
RM
Department of Surgery, University of Toronto, Canada.
Kiziroglu
F
F
D000069594:Abatacept; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000494:pharmacology*; D001402:B-Lymphocytes / Q000276:immunology*; D060908:CTLA-4 Antigen; D006084:Graft Rejection / Q000276:immunology*; D006085:Graft Survival / Q000276:immunology*; D018796:Immunoconjugates; D007376:Interleukin-2 / Q000032:analysis; D015847:Interleukin-4 / Q000032:analysis; D008213:Lymphocyte Activation; D017710:Lymphocyte Transfusion; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D015778:Minor Histocompatibility Antigens / Q000276:immunology; D011993:Recombinant Fusion Proteins / Q000494:pharmacology; D016038:Skin Transplantation / Q000276:immunology*; D013045:Species Specificity; D013154:Spleen / Q000276:immunology; D014184:Transplantation, Homologous
D015703:Antigens, CD; D000943:Antigens, Differentiation; D060908:CTLA-4 Antigen; C556707:Ctla4 protein, mouse; D018796:Immunoconjugates; D007376:Interleukin-2; D015778:Minor Histocompatibility Antigens; D011993:Recombinant Fusion Proteins; D015847:Interleukin-4; D000069594:Abatacept