Antimicrobial susceptibility of Listeria monocytogenes isolated from meningoencephalitis in sheep.
The antimicrobial susceptibility to different antimicrobial agents of 41 Listeria monocytogenes strains isolated from sheep with meningoencephalitis and from feedstuff was tested by both microdilution and disk diffusion methods. Both sets of isolates of L. monocytogenes were susceptible to penicillin G, amoxicillin, cephalothin, erythromycin, vancomycin, rifampicin, gentamicin, kanamycin, trimethoprim, sulfisoxazole, chloramphenicol and ciprofloxacin, but resistant to tetracycline and doxycycline (7.3 and 4.9%, respectively). Tetracycline was the most frequent resistance trait in L. monocytogenes strains of animal origin. Four strains (9.8%) also exhibited reduced susceptibility (MIC 4 mg/l) to doxycycline suggesting the need of surveillance studies to monitor the antimicrobial resistance of Listeria strains of animal origin.
Departamento Patología Animal I (Sanidad Animal), Facultad de Veterinaria, Universidad Complutense, 28040 Madrid, Spain.
A I
AI
Vela
J F
JF
Fernández-Garayzábal
M V
MV
Latre
A A
AA
Rodríguez
L
L
Domínguez
M A
MA
Moreno
D000658:Amoxicillin / Q000494:pharmacology; D000821:Animal Feed / Q000382:microbiology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001921:Brain / Q000382:microbiology; D002511:Cephalosporins / Q000494:pharmacology; D002512:Cephalothin / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D004318:Doxycycline / Q000494:pharmacology; D004352:Drug Resistance, Microbial / Q000235:genetics; D004917:Erythromycin / Q000494:pharmacology; D005839:Gentamicins / Q000494:pharmacology; D007612:Kanamycin / Q000494:pharmacology; D008089:Listeria monocytogenes / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D008088:Listeriosis / Q000662:veterinary*; D008590:Meningoencephalitis / Q000662:veterinary*; D008826:Microbial Sensitivity Tests; D010400:Penicillin G / Q000494:pharmacology; D010406:Penicillins / Q000494:pharmacology; D012293:Rifampin / Q000494:pharmacology; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology*; D013444:Sulfisoxazole / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology; D014295:Trimethoprim / Q000494:pharmacology; D014640:Vancomycin / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D005839:Gentamicins; D010406:Penicillins; D007612:Kanamycin; D002939:Ciprofloxacin; D004917:Erythromycin; D002701:Chloramphenicol; D014640:Vancomycin; D013444:Sulfisoxazole; D000658:Amoxicillin; D014295:Trimethoprim; D013752:Tetracycline; D004318:Doxycycline; D010400:Penicillin G; D002512:Cephalothin; D012293:Rifampin