Gene therapy of malignant gliomas: a pilot study of vaccination with irradiated autologous glioma and dendritic cells admixed with IL-4 transduced fibroblasts to elicit an immune response.
Department of Neurological Surgery, University of Pittsburgh Medical Center, PA 15213, USA.
H
H
Okada
I F
IF
Pollack
F
F
Lieberman
L D
LD
Lunsford
D
D
Kondziolka
D
D
Schiff
J
J
Attanucci
H
H
Edington
W
W
Chambers
P
P
Kalinski
D
D
Kinzler
T
T
Whiteside
E
E
Elder
D
D
Potter
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001932:Brain Neoplasms / Q000235:genetics* / Q000276:immunology / Q000532:radiotherapy / Q000628:therapy*; D019496:Cancer Vaccines / Q000235:genetics*; D002455:Cell Division; D002478:Cells, Cultured; D016207:Cytokines / Q000096:biosynthesis; D003713:Dendritic Cells / Q000276:immunology / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005347:Fibroblasts / Q000276:immunology / Q000378:metabolism*; D005434:Flow Cytometry; D005910:Glioma / Q000235:genetics* / Q000276:immunology / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans; D007150:Immunohistochemistry; D015847:Interleukin-4 / Q000235:genetics*; D007937:Leukapheresis; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D010865:Pilot Projects; D051381:Rats; D012190:Retroviridae / Q000235:genetics; D013602:T-Lymphocytes, Cytotoxic / Q000378:metabolism; D014161:Transduction, Genetic; D016896:Treatment Outcome
D019496:Cancer Vaccines; D016207:Cytokines; D015847:Interleukin-4