Emerging technologies in yeast genomics.
The genomic revolution is undeniable: in the past year alone, the term 'genomics' was found in nearly 500 research articles, and at least 6 journals are devoted solely to genomic biology. More than just a buzzword, molecular biology has genuinely embraced genomics (the systematic, large-scale study of genomes and their functions). With its facile genetics, the budding yeast Saccharomyces cerevisiae has emerged as an important model organism in the development of many current genomic methodologies. These techniques have greatly influenced the manner in which biology is studied in yeast and in other organisms. In this review, we summarize the most promising technologies in yeast genomics.
Kumar
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Department of Molecular, Cellular and Developmental Biology, Yale University, PO Box 208103, New Haven, Connecticut 06520-8103, USA.
Snyder
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D001665:Binding Sites; D001709:Biotechnology / Q000379:methods / Q000639:trends; D004251:DNA Transposable Elements / Q000235:genetics; D004268:DNA-Binding Proteins / Q000378:metabolism; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism; D017353:Gene Deletion; D020869:Gene Expression Profiling; D016681:Genome, Fungal; D023281:Genomics / Q000379:methods* / Q000639:trends; D020407:Internet; D013058:Mass Spectrometry; D008957:Models, Genetic; D016296:Mutagenesis / Q000235:genetics; D020411:Oligonucleotide Array Sequence Analysis; D020543:Proteome; D020798:Two-Hybrid System Techniques; D015003:Yeasts / Q000235:genetics*
D004251:DNA Transposable Elements; D004268:DNA-Binding Proteins; D005656:Fungal Proteins; D020543:Proteome