Pericarditis after allogeneic peripheral blood stem cell transplantation caused by Legionella pneumophila (non-serogroup 1).
A case of Legionella pericarditis caused by a Legionella pneumophila isolate other than serogroup 1 is reported in a 59-year-old man after allogeneic peripheral blood stem cell transplantation. On admission a 5 mm pericardial effusion was detected on echocardiography. Antibodies were detected against L. pneumophila serogroups 7 to 14 using the antigen pool and against serogroup 12 alone. Antibodies were not detected against the serogroup 1 to 6 antigen pool. The patient's clinical condition improved dramatically after treatment with clarithromycin and an echocardiography revealed the total disappearance of the pericardial effusion.
Institute for Medical Microbiology and Epidemiology of Infectious Diseases, University of Leipzig, Germany. schaur@medizin.uni-leipzig.de
R
R
Schaumann
W
W
Pönisch
J H
JH
Helbig
U
U
Hegenbart
G
G
Ackermann
J
J
Hofmann
D
D
Niederwieser
A C
AC
Rodloff
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000032:analysis; D017291:Clarithromycin / Q000627:therapeutic use; D004452:Echocardiography; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D016952:Legionella pneumophila / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010490:Pericardial Effusion / Q000382:microbiology*; D010493:Pericarditis / Q000188:drug therapy / Q000209:etiology*; D012703:Serotyping; D014184:Transplantation, Homologous
D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D017291:Clarithromycin