Group-selective hydroalumination: a novel route to stereogenic tert-alcohol centers.
[reaction: see text]. A new group-selective reaction is described, that is, the hydroalumination of bis-alkynyl alcohols armed with an adjacent stereogenic center, giving stereo-defined tert-alcohols of potential utility in natural product synthesis.
Department of Chemistry, Tokyo Institute of Technology, and CREST, Japan Science and Technology Corporation, O-okayama, Meguro-ku, Tokyo 152-8551, Japan.
K
K
Ohmori
T
T
Suzuki
K
K
Taya
D
D
Tanabe
T
T
Ohta
K
K
Suzuki