The course of tardive dyskinesia and parkinsonism in psychiatric inpatients: 14-year follow-up.
Tardive dyskinesia and parkinsonism were assessed in 53 patients residing in a state psychiatric hospital in 1984 and 1998. A 4.0-point decrease in the mean Abnormal Involuntary Movement Scale score (6.0 versus 2.0; p < 0.001) and a 3.5-point increase in the Rating Scale for Extrapyramidal Signs score (2.8 versus 6.3; p < 0.001) were noted between 1984 and 1998. Over a 14-year period, tardive dyskinesia improved and parkinsonism worsened in patients who continued to receive neuroleptic drugs.
Division of Neurology, Memorial Hospital of Rhode Island, Pawtucket 02860, USA. fernandezh@pol.net
H H
HH
Fernandez
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Krupp
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JH
Friedman
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020820:Dyskinesias / Q000503:physiopathology* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology* / Q000523:psychology; D012559:Schizophrenia / Q000503:physiopathology*; D012565:Schizophrenic Psychology