[Macro-CK disclosing disseminated epidermoid carcinoma of the pyriform sinus in a patient with dermatomyositis].
BACKGROUND
The association between dermatomyositis and cancer is clearly established, but its frequency remains difficult to define.


METHODS
We report the case of an association between a dermatomyositis and a cancer of the piriform antrum. Four months after surgical treatment and radiotherapy, the increased macro-CK level gave us reason to suspect a cancer relapse with pulmonary, hepatic, splenic and renal metastases without progressive clinical signs.


CONCLUSIONS
Mitochondrial macro-CK detection must evoke the presence of neoplasia with or without metastasis, which would be a poor prognosis, as has been shown in our patient.
Bonnet
S
S
Clinique de médecine interne et maladies infectieuses, hôpital Haut-Lévêque, 5, avenue de Magellan, 33604 Pessac, France.
Mercié
P
P
Lacape
G
G
Viallard
J F
JF
Faure
I
I
Martel
J
J
Couzi
L
L
Leng
B
B
Pellegrin
J L
JL
D002294:Carcinoma, Squamous Cell / Q000097:blood / Q000175:diagnosis*; D003402:Creatine Kinase / Q000097:blood*; D003882:Dermatomyositis / Q000150:complications*; D006801:Humans; D046911:Macromolecular Substances; D008297:Male; D008875:Middle Aged; D010610:Pharyngeal Neoplasms / Q000097:blood / Q000175:diagnosis*
D046911:Macromolecular Substances; D003402:Creatine Kinase