[Evaluation of cochlear function by means of otoacoustic emission in children treated with cytostatic drugs in the course of bone marrow proliferative diseases].
The aim of study was cochlear function estimation by means otoacoustic emission in children treated by leukaemia cytostatic drugs in course of the bone marrow proliferative diseases. The children after treatment of acute lymphoblastic leukemia or nongranulomatic malignant lymphoma according to BFM programme were examined in this study. Audiologic examination of children included tonal audiometry, tympanometry and otoacoustic emission as well. The results were compared to the findings of control group consisted of healthy children have never suffered from ear diseases and have never used ototoxic drugs. No significant differences in tonal audiometry and TEOAE were observed. Aggressive treatment of leukaemia does not result in hearing loss.
II Katedra i Klinika Laryngologii Slaskiej AM w Zabrzu.
G
G
Namysłowski
G
G
Trybalska
K
K
Morawski
W
W
Scierski
P
P
Urbaniec
D
D
Sońta-Jakimczyk
A
A
Janik-Moszant
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D001301:Audiometry, Pure-Tone; D002648:Child; D003051:Cochlea / Q000187:drug effects*; D005260:Female; D034381:Hearing Loss / Q000139:chemically induced* / Q000175:diagnosis*; D006801:Humans; D008223:Lymphoma / Q000188:drug therapy*; D008297:Male; D017084:Otoacoustic Emissions, Spontaneous; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*