Familial occurrence of nevus sebaceus of Jadassohn: another case of paradominant inheritance?
We describe two sibs (a boy and a girl) suffering from linear nevus sebaceus of Jadassohn. The parents are not affected. This rare pattern of familial occurrence prompts us to suggest that these sibs represent a case of paradominant inheritance of a mosaic disorder.
Department of Dermatology, Policlinico Umberto I, University "La Sapienza", Rome, Italy.
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Laino
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Steensel
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Innocenzi
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Camplone
D002648:Child; D005260:Female; D020022:Genetic Predisposition to Disease; D006222:Hamartoma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male; D009030:Mosaicism; D009679:Nuclear Family; D012535:Scalp; D012626:Sebaceous Gland Neoplasms / Q000235:genetics* / Q000473:pathology