Analysis of the isoform of Xenopus euakryotic translation initiation factor 4E.
We have found two isoforms of the eukaryotic translation initiation factor 4E (eIF4E) in Xenopus laevis. These proteins differ in length by 18 amino acids. Overexpression of either of the two eIF4E proteins modestly increase translation in Xenopus oocytes. The results suggest that both of these two isoforms function in translation.
Institute for Biomolecular Science, Gakushuin University, Tokyo, Japan.
M
M
Wakiyama
A
A
Suzuki
M
M
Saigoh
N
N
Sakai
H
H
Miyoshi
S
S
Kojima
K
K
Miura
D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D000818:Animals; D015153:Blotting, Western; D039561:Eukaryotic Initiation Factor-4E; D017930:Genes, Reporter; D008156:Luciferases / Q000235:genetics / Q000378:metabolism; D008845:Microinjections; D008969:Molecular Sequence Data; D009865:Oocytes / Q000502:physiology; D010448:Peptide Initiation Factors / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D014176:Protein Biosynthesis; D020033:Protein Isoforms; D014982:Xenopus laevis / Q000235:genetics* / Q000378:metabolism
D039561:Eukaryotic Initiation Factor-4E; D010448:Peptide Initiation Factors; D020033:Protein Isoforms; D008156:Luciferases