Regulation of ionic homeostasis by mammalian embryos.
Control and regulation of cellular homeostasis are essential for normal embryo development and maintenance of viability. By understanding the role of ionic homeostasis in normal cell development and homeostatic control by the developing embryo, it is possible to develop culture systems that minimize cellular stress and therefore maintain embryo viability. This article discusses the regulation of intracellular levels of protons (pHi), calcium, magnesium, and phosphate in mammalian embryos.
Lane
M
M
Colorado Center for Reproductive Medicine, 799 East Hampden Avenue, Suite 520, Englewood, CO 80110, USA.
Gardner
D K
DK
D000818:Animals; D002118:Calcium / Q000378:metabolism; D003470:Culture Media; D046508:Culture Techniques; D003599:Cytoskeleton / Q000502:physiology; D004622:Embryo, Mammalian / Q000502:physiology*; D004625:Embryo, Nonmammalian; D006706:Homeostasis; D006863:Hydrogen-Ion Concentration; D007477:Ions; D008274:Magnesium / Q000378:metabolism; D009865:Oocytes / Q000502:physiology / Q000648:ultrastructure; D010710:Phosphates / Q000378:metabolism
D003470:Culture Media; D007477:Ions; D010710:Phosphates; D008274:Magnesium; D002118:Calcium