Psychiatric issues in epilepsy.
In recent years there has been considerable research interest at the interface between epilepsy and psychiatry. Topics of interest include the epidemiology of psychiatric co-morbidity in epilepsy; clinical syndromes at this interface and their classification; the relationship between cognitive dysfunction and psychiatric co-morbidity; biological mechanisms that mediate such co-morbidity, especially with developments in imaging and genetic research; the association between temporal lobe surgery, vagus nerve stimulation, and other non-pharmacological treatments, and the development of such co-morbidity; the contribution of anticonvulsant drugs towards the development of psychiatric co-morbidity; quality of life and other psychosocial issues; and non-epileptic attack disorder. In this review, papers on these psychiatric issues in epilepsy, with a focus on those published in the past year (October 1999 to October 2000) are critically evaluated, and some important current issues at this interface are considered in detail.
University Department of Clinical Neurology, Institute of Neurology (University College London), London, UK. e.s.krishnamoorthy@ion.ucl.ac.uk
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Krishnamoorthy
D000927:Anticonvulsants / Q000009:adverse effects; D004827:Epilepsy / Q000150:complications* / Q000503:physiopathology / Q000523:psychology*; D006801:Humans; D001523:Mental Disorders / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology*; D012640:Seizures / Q000175:diagnosis / Q000503:physiopathology; D013702:Temporal Lobe / Q000473:pathology / Q000503:physiopathology
D000927:Anticonvulsants