[Role of opiate system in mechanisms of formation of alcohol-dependence].
Effect of naloxon on the activity of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in the blood serum and content of catecholamines (CA) in the brain structures (hypothalamus, midbrain, new cortex) and blood of rats under alcoholic dependence were studied. Participation of opiate structures of receptors in formation of alcoholic dependence is shown.
Kharchenko
N K
NK
Ukrainian Scientific Research Institute of Social and Forensic Psychiatry, Ukrainian Ministry of Public Health, Kyiv, Ukraine.
D000426:Alcohol Dehydrogenase / Q000097:blood; D000437:Alcoholism / Q000209:etiology* / Q000378:metabolism; D000444:Aldehyde Dehydrogenase / Q000097:blood; D000818:Animals; D001923:Brain Chemistry; D002395:Catecholamines / Q000378:metabolism; D009270:Naloxone / Q000494:pharmacology; D009292:Narcotic Antagonists / Q000494:pharmacology; D018847:Opioid Peptides / Q000502:physiology*; D051381:Rats; D011957:Receptors, Opioid / Q000378:metabolism
D002395:Catecholamines; D009292:Narcotic Antagonists; D018847:Opioid Peptides; D011957:Receptors, Opioid; D009270:Naloxone; D000426:Alcohol Dehydrogenase; D000444:Aldehyde Dehydrogenase