Skin occlusion and irritant and allergic contact dermatitis: an overview.
Occlusion, widely used to enhance percutaneous absorption of drugs, also increases penetration of other chemicals and antigens, and hence may exacerbate irritant and allergic contact dermatitis. This overview summarizes the adverse effects of occlusion.
Zhai
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Department of Dermatology, University of California, School of Medicine, Box 0989, Surge 110, San Francisco, CA 94143-0989, USA.
Maibach
H I
HI
D000818:Animals; D017449:Dermatitis, Allergic Contact / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D007509:Irritants / Q000009:adverse effects*; D009779:Occlusive Dressings / Q000009:adverse effects*; D012867:Skin / Q000473:pathology / Q000503:physiopathology*; D014870:Water Loss, Insensible / Q000187:drug effects
D007509:Irritants