Human immunodeficiency viruses types 1 and 2 infection among replacement blood donors in Mumbai (Bombay).
Between 1993-96, blood donated by 12,235 replacement blood donors was screened by various Enzyme Linked Immunosorbent Assays for detecting antibodies to Human Immunodeficiency Viruses types 1 and 2 according to the guidelines specified by Indian--Food and Drug Administration. 222 replacement blood donors (1.81%) were found to be seropositive for antibodies to Human Immunodeficiency Virus types 1 and 2. Furthermore, the ImmunoComb II HIV 1 & 2 BiSpot rapid sandwich ELISA in a comb format was used for differentially identifying HIV-1 and/or HIV-2 infection among these blood donors in Mumbai. Our data indicates that there is a low seroprevalence of HIV-1-2 infection among replacement blood donors in Mumbai (Bombay). Among them, while HIV-1 is still the predominant virus, dual HIV-1-2 and HIV-2 only infections are steadily increasing.
Department of Microbiology, Topiwala National Medical College and B.Y.L., Nair Municipal Hospital, Mumbai Central, Mumbai (Bombay)-400 008. hakamat@xtra.co.nz
H A
HA
Kamat
D D
DD
Banker
G V
GV
Koppikar
D015492:AIDS Serodiagnosis; D001782:Blood Donors; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015483:HIV Antibodies / Q000097:blood*; D006679:HIV Seropositivity / Q000453:epidemiology*; D015497:HIV-1 / Q000302:isolation & purification*; D015498:HIV-2 / Q000302:isolation & purification*; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male
D015483:HIV Antibodies