[Specific IgG and specific IgG subclass in allergic rhinitis].
Using enzyme-linked immunosorbent assay, we detected the levels of total IgE, caddis fly specific IgE and caddis fly specific IgG subclass in 60 patients with caddis fly allergic rhinitis. The results showed that the levels of SIgE (30.60 +/- 0.78) of patients were significantly higher than that of the controls (P < 0.001). Same results were received in the levels of specific IgG2 and IgG4. The differences of specific IgE and specific IgG4 between the groups before treatment and after treatment were also significant (Specific IgE before treatment: 30.60 +/- 0.78, after treatment: 1.58 +/- 0.44, P < 0.001; specific IgG4 before treatment: 383.31 +/- 96.48, after treatment: 233.68 +/- 80.94, P < 0.001). We conclude that specific IgG subclass has obviously etiologic specificity and sensitivity.
First Affiliated of Chongqing University of Medical Sciences, Chongqing 400016.
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Hong
D000293:Adolescent; D000328:Adult; D000818:Animals; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D007074:Immunoglobulin G / Q000097:blood* / Q000145:classification; D007313:Insecta; D008297:Male; D008875:Middle Aged; D012221:Rhinitis, Allergic, Perennial / Q000276:immunology*
D007074:Immunoglobulin G; D007073:Immunoglobulin E