Neurocysticercosis case with a single cyst in the brain showing dramatic drop in specific antibody titers within 1 year after curative surgical resection.
We report on one Japanese case subject with neurocysticercosis (NCC) who had a single cyst in the brain and had undergone curative surgical resection. Pathological examination revealed that it was a cysticercus of Taenia solium. Serological examination of the pair serum samples just before and 1 year after surgery revealed that antibody responses against the glycoproteins, highly specific to NCC and detected in the serum sample just before surgery by both immunoblot and ELISA became negative within 1 year after the surgery. It is, therefore, strongly suggested that this case had a single cysticercus in his whole body and the presence of a single cysticercus was sufficient to evoke antibody responses against it.
Ito
A
A
Department of Parasitology, Asahikawa Medical College, Japan. akiraito@asahikawa-med.ac.jp
Nakao
M
M
Ito
Y
Y
Yuzawa
I
I
Morishima
H
H
Kawano
N
N
Fujii
K
K
D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D001921:Brain / Q000000981:diagnostic imaging / Q000469:parasitology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020019:Neurocysticercosis / Q000175:diagnosis* / Q000469:parasitology / Q000601:surgery; D013621:Taenia / Q000254:growth & development / Q000276:immunology* / Q000302:isolation & purification; D014057:Tomography, X-Ray Computed
D000909:Antibodies, Helminth