Immune-mediated vasculitis in a shar-pei with swollen hock syndrome.
A castrated male shar-pei was presented for episodes of lethargy, swelling of the tarsal joints, and polydipsia with polyuria. Histological examination of biopsies from skin overlying the tarsi and direct immunoperoxidase immunohistochemical staining confirmed immune complex vasculitis, suggesting a role for immune complex deposition in the pathogenesis of shar-pei fever.
Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4.
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D000818:Animals; D004283:Dog Diseases / Q000276:immunology / Q000503:physiopathology; D004285:Dogs; D006614:Hindlimb / Q000503:physiopathology; D008297:Male; D014657:Vasculitis / Q000276:immunology / Q000503:physiopathology / Q000662:veterinary*