Technologies for the design, discovery, formulation and administration of vaccines.
This paper summarizes major technologies, with emphasis on applications to preventive vaccines for infectious diseases. A limited number of examples of each technology are provided.
BioChem Pharma, Inc., Northborough, MA 01532, USA. ellisr@biochempharma.com
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D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D001428:Bacterial Vaccines / Q000235:genetics / Q000302:isolation & purification; D002626:Chemistry, Pharmaceutical; D016503:Drug Delivery Systems; D015195:Drug Design; D005822:Genetic Vectors; D006801:Humans; D009154:Mutation; D014612:Vaccines / Q000008:administration & dosage* / Q000235:genetics / Q000302:isolation & purification*; D014613:Vaccines, Attenuated / Q000302:isolation & purification; D018074:Vaccines, Conjugate / Q000302:isolation & purification; D019444:Vaccines, DNA / Q000302:isolation & purification; D015164:Vaccines, Inactivated / Q000302:isolation & purification; D014614:Vaccines, Synthetic / Q000302:isolation & purification; D014765:Viral Vaccines / Q000235:genetics / Q000302:isolation & purification
D000276:Adjuvants, Immunologic; D001428:Bacterial Vaccines; D014612:Vaccines; D014613:Vaccines, Attenuated; D018074:Vaccines, Conjugate; D019444:Vaccines, DNA; D015164:Vaccines, Inactivated; D014614:Vaccines, Synthetic; D014765:Viral Vaccines