Second-order selection in bacterial evolution: selection acting on mutation and recombination rates in the course of adaptation.
The increase in genetic variability of a population can be selected during adaptation, as demonstrated by the selection of mutator alleles. The dynamics of this phenomenon, named second-order selection, can result in an improved adaptability of bacteria through regulation of all facets of mutation and recombination processes.
Tenaillon
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O
Inserm E9916, Faculté de médecine Necker Enfants Malades, Université Paris V, France. tenaillo@necker.fr
Taddei
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F
Radmian
M
M
Matic
I
I
D000222:Adaptation, Physiological / Q000235:genetics*; D001419:Bacteria / Q000235:genetics* / Q000254:growth & development; D005075:Biological Evolution; D009154:Mutation / Q000235:genetics*; D011995:Recombination, Genetic / Q000235:genetics; D012641:Selection, Genetic