Primary lung cancer associated with polymyositis/dermatomyositis, with a review of the literature.
It has been suggested that lung cancer is frequently associated with polymyositis/dermatomyositis (PM/DM). The purpose of this study was to describe the clinical features of primary lung cancer associated with PM/DM. We first describe the clinical features of two cases treated in our hospital, and then provide a review of the literature. Finally, 24 patients (five females and 19 males) with primary lung cancer associated with PM/DM are retrospectively evaluated. Histological types of lung cancer were as follows: small cell lung cancer (n = 7), squamous cell carcinoma (n = 5), adenocarcinoma (n = 2), others (n = 5), and unknown (4). The onset of PM/DM is frequently observed before the detection of lung cancer. This is the first report to describe the clinical features of lung cancer associated with PM/DM.
First Department of Internal Medicine, Kagawa Medical University,  Japan.
J
J
Fujita
M
M
Tokuda
S
S
Bandoh
Y
Y
Yang
Y
Y
Fukunaga
S
S
Hojo
Y
Y
Ueda
N
N
Dobashi
K
K
Dohmoto
T
T
Ishida
J
J
Takahara
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000150:complications* / Q000556:secondary; D018196:Carcinoma, Adenosquamous / Q000150:complications / Q000556:secondary; D018288:Carcinoma, Small Cell / Q000150:complications / Q000556:secondary; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000556:secondary; D003882:Dermatomyositis / Q000209:etiology* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed