Phenotypic differerencss in African Americans with Prader-Willi syndrome.
We report on 10 African Americans with Prader-Willi syndrome whose features differ from those of white patients with this condition. Growth is less affected, hand and foot lengths usually are normal, and the facies are atypical; this may lead to underdiagnosis in this population. We encourage clinicians to recognize these phenotypic differences so that diagnosis is not overlooked.
Department of Pediatrics, University of Washington School of Medicine and Children Hospital and Regional Medical Center, Seattle 98105-0371, USA. ihudgins@u.washington.edu
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L
Hudgins
J S
JS
Geer
S B
SB
Cassidy
D000293:Adolescent; D000328:Adult; D001741:Black or African American; D002648:Child; D002657:Child Development; D002675:Child, Preschool; D019066:Facies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010641:Phenotype; D011218:Prader-Willi Syndrome / Q000208:ethnology* / Q000473:pathology*