FTY720, a novel immunosuppressive agent with insulinotropic activity, prolongs graft survival in a mouse islet transplantation model.
Fu
F
F
Novartis Pharmaceuticals Corp, Transplantation Research Department, Summit, New Jersey, USA.
Hu
S
S
Li
S
S
DeLeo
J
J
Hoover
J
J
Wang
S
S
Lake
P
P
Shi
V
V
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000628:therapy; D000068876:Fingolimod Hydrochloride; D006085:Graft Survival / Q000187:drug effects*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007515:Islets of Langerhans / Q000187:drug effects* / Q000502:physiology; D016381:Islets of Langerhans Transplantation / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D011409:Propylene Glycols / Q000494:pharmacology*; D051381:Rats; D011917:Rats, Inbred Lew; D013110:Sphingosine / Q000031:analogs & derivatives; D014183:Transplantation, Heterologous
D007166:Immunosuppressive Agents; D011409:Propylene Glycols; D000068876:Fingolimod Hydrochloride; D013110:Sphingosine