Effect of cold stress in early postnatal ontogeny on blood pressure and heart activity in normo- and hypertensive rats.
Cold stress in the early postnatal ontogeny caused permanent functional changes in the cardiovascular system, which were different in hypertensive NISAG and normotensive WAG rats. Stress led to elevation of blood pressure and overload on the left heart chambers in adult WAG rats postnatally exposed to cold. At the same time, postnatal exposure to cold stress attenuated functional disturbances typical of hypertensive NISAG rats.
Makhanova
N A
NA
Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
Markel'
A L
AL
Jacobson
G S
GS
D000818:Animals; D001794:Blood Pressure; D003080:Cold Temperature / Q000009:adverse effects; D004562:Electrocardiography; D006321:Heart / Q000503:physiopathology; D006973:Hypertension / Q000209:etiology* / Q000503:physiopathology*; D008297:Male; D051381:Rats; D012149:Restraint, Physical; D013312:Stress, Physiological / Q000150:complications* / Q000503:physiopathology*; D013564:Sympathetic Nervous System / Q000503:physiopathology