[The evaluation of 156 cycles of intracytoplasmic sperm injection in the management of male infertility and idiopathic infertility].
OBJECTIVE
The aim of this study was to examine, retrospectively, the efficacy of intracytoplasmic sperm injection (ICSI) in the treatment of male infertility and idiopathic infertility.


METHODS
From November 1995 to January 1998, 140 couples (156 cycles) received ICSI because of severe male factor infertility or idiopathic infertility in our assisted reproductive technology center. The treatment cycles were divided into two groups, group I included 74 cycles done before May 1997, group II included 82 cycles done after May 1997. Mature oocytes were selected for microinjection.


RESULTS
No differences were observed between the two groups in the number of mature oocyte and the total cleavage rate. Oocyte survival rate, normal fertilization rate, embryos of good morphology rate and clinical pregnancy rate were significantly higher in group II than that in group I.


CONCLUSIONS
ICSI procedure does affect the quality of embryos. With the improvement of ICSI technique, ICSI should be the treatment of choice for male infertility and idiopathic infertility.
First Affiliated Hospital of Sun Yet-Sen University of Medical Sciences, Guangzhou 510080.
R
R
Li
G
G
Zhuang
C
C
Zhou
D000328:Adult; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000628:therapy; D007248:Infertility, Male / Q000276:immunology / Q000628:therapy*; D008297:Male; D008845:Microinjections / Q000379:methods; D008875:Middle Aged; D009865:Oocytes; D011247:Pregnancy; D012099:Reproductive Techniques; D012189:Retrospective Studies; D013094:Spermatozoa