Asymmetric 1,3-dipolar cycloaddition of a (Z)-alkene dipolarophile. Synthesis of (3S,4R) ethyl 1-azabicyclo[2.2.1]heptane-3-carboxylate.
Carey
J S
JS
Synthetic Chemistry, GlaxoSmithKline Pharmaceuticals, Old Powder Mills, Nr. Leigh, Tonbridge, Kent, TN11 9AN. UK. John_S_Carey@sbphrd.com