Effect of eugenol and tincture of crataegus (TCR) on in vitro oxidation of LDL + VLDL isolated from plasma of non-insulin dependent diabetic patients.
The present study was carried out to study the effect of antioxidants on oxidised LDL + VLDL and found that vitamin E, eugenol and tincture of crataegus (antioxidants) inhibited oxidation of (LDL + VLDL) similar to standard antioxidant (butylated hydroxy toluene). Vitamin C acted as an antioxidant at lower concentration, and prooxidant at higher concentration.
Department of Biochemistry and Molecular Biology, University of Madras Guindy Campus, Chennai 600 025, India.
K
K
Rajalakshmi
P
P
Gurumurthi
S N
SN
Devaraj
D000975:Antioxidants / Q000494:pharmacology; D027825:Crataegus; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D005054:Eugenol / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D010084:Oxidation-Reduction; D010936:Plant Extracts / Q000494:pharmacology*; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
D000975:Antioxidants; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D010936:Plant Extracts; D017392:Thiobarbituric Acid Reactive Substances; D005054:Eugenol; C007145:crataegus extract