Ofloxacin induced arthropathy in patients with multi-drug resistance tuberculosis.
Some of the 4-fluroquinolones have been reported to induce arthropathy, but so far there are no case reports of arthropathy due to ofloxacin. Two cases of ofloxacin induced arthropathy in multi-drug resistance (MDR) tuberculosis are reported and possible drug interaction with other anti-tubercular drugs is discussed.
Department of Tuberculosis and Chest Diseases, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry-605 006.
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Tumbanatham
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Vinodkumar
D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001168:Arthritis / Q000139:chemically induced*; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007194:India; D015242:Ofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D014388:Tuberculosis, Lymph Node / Q000188:drug therapy*; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy*
D000995:Antitubercular Agents; D015242:Ofloxacin