[Cytomegalovirus antigenemia assay as a useful tool for early diagnosis and therapy for cytomegalovirus infections in three cases with collagen diseases].
We report here three cases of collagen diseases with cytomegalovirus infections. (1) A 21-year-old female, who had been diagnosed as systemic lupus erythematosus, lupus nephritis and lupus peritonitis, had fever. Cytomegalovirus antigenemia (CMV-Ag) assay was 10/8 positive. (2) A 33-year-old female, who had been diagnosed as Wegener glanulomatosis, had fever and liver dysfunction. CMV-Ag assay was 933/896 positive. (3) A 64-year-old female, who had been diagnosed as microscopic polyangitis, had fever, liver dysfunction and pneumonia. CMV-Ag assay was 6/2 positive. They were considered to be complicated with CMV infections. We could make early diagnoses of CMV infection by using CMV-Ag assay and treat them with anti-CMV therapy effectively.
Tsuji
T
T
First Department of Internal Medicine, Yokohama City University School of Medicine.
Misumi
M
M
Inoue
Y
Y
Ideguchi
H
H
Okubo
T
T
Ueda
A
A
Ohno
S
S
Hagiwara
E
E
Aoki
A
A
Ishigatsubo
Y
Y
D000328:Adult; D000368:Aged; D000956:Antigens, Viral / Q000097:blood*; D003095:Collagen Diseases / Q000150:complications* / Q000188:drug therapy; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects
D000956:Antigens, Viral