[Is detection of schizocytes by computerised image analysis accurate?].
Schistocytes result from red cell fragmentation. The identification of the schistocytes is critical for decisions on appropriate management of the patients. Currently, a systematic approach to the counting method remains rewarded. We programmed a computer image analysis device (Q-Win, Leica) in order to detect fragmented red cells. A good correlation between the computer and a well-trained biologist was found after minor modifications of the computer's results. Image analysis should reduced the biologist-to-biologist variation and improve the identification and enumeration of the schistocytes.
Salignac
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Service d'hématologie biologique, CHU Brabois, 54511 VandOEuvre-lès-Nancy.
Campedel
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Bordigoni
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Lecompte
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Lesesve
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JF
D016001:Confidence Intervals; D003584:Cytological Techniques / Q000592:standards; D004906:Erythrocyte Count; D004909:Erythrocyte Indices; D006461:Hemolysis; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D015588:Observer Variation; D012680:Sensitivity and Specificity