Disseminated scabies evolving in a patient undergoing induction chemotherapy for acute myeloblastic leukaemia.
We report on a 34-year-old refugee from the Balkans presenting with a generalized papular rash during induction chemotherapy for acute myeloblastic leukaemia (AML M4eo). This rash appeared on day 5 of the chemotherapy and was diagnosed as disseminated scabies. It was successfully treated with a combination of oral ivermectin and topical lindane. Scabies disappeared completely despite ongoing neutropenia and other severe infectious complications. Disseminated scabies should be included in the differential diagnosis of rash in severely immunosuppressed patients coming from poor housing conditions.
Trendelenburg
M
M
Department of Hematology, Medical Clinic B, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland. trendelenbur@ubaclu.unibas.ch
Büchner
S
S
Passweg
J
J
Rätz Bravo
A R
AR
Gratwohl
A
A
D000328:Adult; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D008297:Male; D012532:Scabies / Q000139:chemically induced*