The influence of genetic predisposition on the prevalence of atopic diseases in Carinthian school children.
The reasons for the origin and increasing rise in incidence of atopic diseases such as bronchial asthma, allergic rhinoconjunctivitis and eczema in many countries are still unknown. Our survey carried out within the frame of the ISAAC protocol comprised three districts in the Austrian province of Carinthia. A complete study of first and second year elementary school children was done in order to uncover a relationship between "presumed exposure" to different possible risk factors with that of an atopic disorder (i.e. asthma, hay fever, eczema). The results show a significant association between the occurrence of atopic disorders and genetic predisposition and the fact that a carpet which had previously been present in the child's bedroom, had been removed due to the presence of an allergic disease in a family member. The logistic regression model explains a very small part of the overall variability (R2 = 7.32%).
Institute of Cancer Research, Division of Epidemiology, University of Vienna.
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T
Waldhoer
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Haidinger
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Feenstra
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Plank
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Vutuc
D016902:Air Pollution, Indoor / Q000009:adverse effects; D000485:Allergens / Q000009:adverse effects; D001317:Austria / Q000453:epidemiology; D002648:Child; D003431:Cross-Cultural Comparison; D003430:Cross-Sectional Studies; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology / Q000235:genetics*; D015994:Incidence; D008297:Male; D012307:Risk Factors; D014028:Tobacco Smoke Pollution / Q000009:adverse effects
D000485:Allergens; D014028:Tobacco Smoke Pollution