Association between interleukin concentration in follicular fluid and intracytoplasmic sperm injection (ICSI) outcome.
OBJECTIVE
The aim of this study was to determine the presence and concentration of interleukin IL-6, IL-8, and granulocyte-macrophage-colony-stimulating factor (GM-CSF) in pre-ovulatory ovarian follicular fluid (FF) of patients undergoing controlled ovarian hyperstimulation for intracytoplasmic sperm injection (ICSI) therapy on one hand, and to find out whether these cytotokine concentrations could be used as a predictive parameter for ICSI outcome.


METHODS
The levels of IL-6, IL-8, and GM-CSF were measured from women that underwent ICSI therapy and the results were compared between the patients who became pregnant after IC
Hammadeh
M E
ME
Department of Obstetrics and Gynecology, The University of Saarland, Homburg/Saar, Germany. frmham@med-rz.uni-sb.de
Ertan
A K
AK
Baltes
S
S
Braemert
B
B
Georg
T
T
Rosenbaum
P
P
Schmidt
W
W
D000328:Adult; D005260:Female; D015571:Follicular Fluid / Q000737:chemistry*; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000032:analysis; D006801:Humans; D007248:Infertility, Male; D015850:Interleukin-6 / Q000032:analysis; D016209:Interleukin-8 / Q000032:analysis; D007378:Interleukins / Q000032:analysis*; D008297:Male; D011247:Pregnancy; D011379:Prognosis; D020554:Sperm Injections, Intracytoplasmic / Q000706:statistics & numerical data*
D015850:Interleukin-6; D016209:Interleukin-8; D007378:Interleukins; D016178:Granulocyte-Macrophage Colony-Stimulating Factor