[The study of some mechanisms of injurious effects of low-frequency noises].
Low-frequency noise has been shown to cause certain functional changes in the organism of laboratory animals that manifest in changes of the state of the regulatory systems and metabolic disturbances at cellular and subcellular levels. The obtained data support the hypothesis of the mechanism of injurious effect of this physical factor including two basically correlated ways, i.e. the central mechanism associated with overexcitation of the hypotalamohypophysis-adrenal system and mediating the homeostatic parameters of the body, and the local one which is determined by a direct effect of low-frequency noise on highly organized structure of membraneous and genetic apparatus of cells.
Institute of Military Medicine, Ministry of Defence of Russian Federation, St. Petersburg, 195043 Russia.
N N
NN
Pluzhnikov
V G
VG
Vladimirov
V N
VN
Zinkin
I V
IV
Voblikov
I N
IN
Vasil'eva
G G
GG
Rodionov
I V
IV
Malysheva
E B
EB
Zhakovko
L A
LA
Sharova
E A
EA
Shibanov
D000818:Animals; D001921:Brain / Q000502:physiology*; D002869:Chromosome Aberrations; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology; D015227:Lipid Peroxidation; D008928:Mitochondria / Q000502:physiology; D009622:Noise / Q000009:adverse effects*; D010913:Pituitary-Adrenal System / Q000502:physiology; D051381:Rats; D013312:Stress, Physiological / Q000209:etiology* / Q000503:physiopathology