Gastric emptying rate for solid and for liquid test meals in patients with dyspeptic symptoms after partial gastrectomy and after vagotomy followed by partial gastrectomy.
OBJECTIVE
Gastric emptying rate for solid and for liquid test meals was investigated retrospectively in patients with longstanding epigastric distress after partial gastrectomy, either as primary treatment or after failure of vagotomy for peptic ulcer in order to find an explanation for the postoperative symptoms.


METHODS
Radionuclide-labeled liquid and solid test meals were used to evaluate gastric emptying rate, at least one year after surgery.


RESULTS
The lag phase for liquid test meals disappeared in all operated patients. Partial gastrectomy usually lead to fast emptying but this resective procedure, if performed after vagotomy, lead to stasis in a significant number of patients. Gastric emptying rate for solids increased in only a few of these symptomatic patients. In most of them however, there was a normal to decreased emptying rate. If a vagotomy had preceded the resective procedure, gastric emptying rate decreased significantly.


CONCLUSIONS
In all these symptomatic patients, gastric emptying had been disturbed for at least one type of test meal. This makes investigation for both meals necessary, especially since there is a lack of correlation. Furthermore, if vagotomy fails to prevent ulcer recurrence, one should carefully consider all options before performing partial gastrectomy since gastric emptying rate after these consecutive procedures worsens considerably.
Mistiaen
W
W
University of Antwerp, Dept. of Anatomy, Groenenborgerlaan 171 2020 Antwerp, Belgium. Mistiaen@ruca.ua.ac.be
Van Hee
R
R
Blockx
P
P
Bortier
H
H
Harrisson
F
F
D000328:Adult; D000368:Aged; D004415:Dyspepsia / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects*; D005746:Gastric Emptying; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000601:surgery; D011178:Postgastrectomy Syndromes / Q000503:physiopathology*; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D016284:Technetium Tc 99m Pentetate; D014628:Vagotomy / Q000009:adverse effects*
D019275:Radiopharmaceuticals; D016284:Technetium Tc 99m Pentetate