Biocatalytic modification of natural products.
Natural products are ideal training compounds for enzymatic catalysis. New transformations have become possible on a preparative scale thanks to molecular biology, which has made many new enzymes available. Additionally, new synthetic pathways have been developed to regenerate expensive cofactors in situ and to improve enzyme selectivity.
Istituto di Biocatalisi e Riconoscimento Molecolare, CNR, Milano, Italy. Rivas@ico.mi.cnr.it
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D000596:Amino Acids / Q000138:chemical synthesis / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000378:metabolism; D001688:Biological Products / Q000138:chemical synthesis* / Q000378:metabolism; D001709:Biotechnology / Q000639:trends; D050260:Carbohydrate Metabolism; D002241:Carbohydrates / Q000138:chemical synthesis*; D002384:Catalysis; D004798:Enzymes / Q000378:metabolism*; D005960:Glucosides / Q000138:chemical synthesis / Q000378:metabolism; D007769:Lactams; D010455:Peptides / Q000138:chemical synthesis / Q000378:metabolism; D013256:Steroids / Q000138:chemical synthesis* / Q000378:metabolism
D000596:Amino Acids; D000900:Anti-Bacterial Agents; D001688:Biological Products; D002241:Carbohydrates; D004798:Enzymes; D005960:Glucosides; D007769:Lactams; D010455:Peptides; D013256:Steroids