Human NK cells lyse porcine endothelial cells via the perforin/granzyme B pathway.
Laboratory for Transplantation Immunology, Department of Internal Medicine, University Hospital Zürich, Zürich, Switzerland.
U B
UB
Matter-Reissmann
P
P
Forte
J D
JD
Seebach
D000818:Animals; D017209:Apoptosis; D003602:Cytotoxicity, Immunologic / Q000276:immunology*; D004730:Endothelium, Vascular / Q000166:cytology / Q000276:immunology*; D019254:Genes, bcl-2; D053804:Granzymes; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D008562:Membrane Glycoproteins / Q000187:drug effects / Q000378:metabolism*; D054353:Perforin; D052899:Pore Forming Cytotoxic Proteins; D012697:Serine Endopeptidases / Q000187:drug effects / Q000378:metabolism*; D013552:Swine; D014162:Transfection; D014183:Transplantation, Heterologous
D008562:Membrane Glycoproteins; D052899:Pore Forming Cytotoxic Proteins; D054353:Perforin; C509213:GZMB protein, human; D053804:Granzymes; D012697:Serine Endopeptidases