Transcranial magnetic stimulation-induced switch into mania: a report of two cases.
BACKGROUND
Transcranial magnetic stimulation is a novel, experimental procedure in the treatment of psychiatric disorders, most notably mood disorders. Transcranial magnetic stimulation is currently being widely studied in other applications, and its efficacies and potential side effects are being investigated.


METHODS
Transcranial magnetic stimulation was administered five times a week for 4 weeks.


RESULTS
In this report, a manic episode followed treatment with transcranial magnetic stimulation in two patients.


CONCLUSIONS
Clinicians should be aware that, like with other antidepressive treatments, a switch into mania might complicate treatment with transcranial magnetic stimulation in bipolar patients.
Department of Psychiatry C, Division of Psychiatry, Sheba Medical Center, Ramat-Gan, Israel.
O T
OT
Dolberg
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S
Schreiber
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L
Grunhaus
D001714:Bipolar Disorder / Q000523:psychology*; D001921:Brain / Q000502:physiology; D003866:Depressive Disorder / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome