Expression databases--resources for pharmacogenomic R&D.
This review aims to outline the primary biological databases that are being generated to understand fundamental biology, identify new drug targets, and to look at compound profiling in a new light. We will give a brief overview of four of the main areas being studied in molecular biology: genomics, pharmacogenomics, pharmacogenetics and proteomics. Looking initially at each data set and some of its potential applications, we will go on to describe some of the potentially enormous advantages gained by fully integrating these data sets.
Incyte Genomics Ltd., Cambridge, UK. mfurness@incyte.com
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Furness
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Henrichwark
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Egerton
D000818:Animals; D016208:Databases, Factual; D015870:Gene Expression / Q000235:genetics*; D006801:Humans; D010597:Pharmacogenetics / Q000706:statistics & numerical data*