[Analysis of polymorphism of the glutathione S-transferase gene in populations of the Volga-Ural region].
The frequency of the GSTM1 gene deletion homozygotes in eight populations of the Volga-Ural region belonging according to linguistic classification to Turkic (Bashkirs, Tatars, and Chuvashs), Finno-Ugric (Maris, Komis, Mordovians, and Udmurts), and Eastern-Slavic (Russians) ethnic groups, was examined by means of PCR technique. The frequency of the deletion homozygotes varied from 41.4% in Bashkirs to 61.3% in Mordovians. The mean deletion frequency comprised 50.1%, which was consistent with the data for European populations (chi 2 = 0.009).
Institute of Biochemistry and Genetics, Ufa Research Center, Russian Academy of Sciences, Ufa, 450054 Bashkortostan.
Iu V
IuV
Vakhitova
Z M
ZM
Sultanaeva
T V
TV
Viktorova
A R
AR
Bikmaeva
E K
EK
Khusnutdinova
D005006:Ethnicity; D017353:Gene Deletion; D005982:Glutathione Transferase / Q000235:genetics*; D006720:Homozygote; D006801:Humans; D011110:Polymorphism, Genetic; D012426:Russia
D005982:Glutathione Transferase