Identification and characterization of a gene encoding a 35-kDa protein from Mycobacterium avium subspecies paratuberculosis.
Mycobacterium avium subspecies paratuberculosis is the causative agent of Johne's disease, a chronic enteritis in ruminants. A gene homologous to that of 35-kDa antigen of Mycobacterium leprae was cloned and sequenced from Mycobacterium paratuberculosis. The database searches revealed 82.79% and 95.67% similarities of its nucleotide sequence, with those of immunodominant 35-kDa protein of M. leprae and M. avium, respectively.
Banasure
K D
KD
National Biotechnology Centre, Indian Research Institute, Izannagar, India.
Basagoudanavar
S H
SH
Chaudhury
P
P
Tiwari
V
V
Parihar
N S
NS
Goswami
P P
PP
D000595:Amino Acid Sequence; D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis / Q000235:genetics*; D001426:Bacterial Proteins / Q000032:analysis / Q000235:genetics*; D002417:Cattle; D003001:Cloning, Molecular; D017124:Conserved Sequence; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D016927:Mycobacterium avium subsp. paratuberculosis / Q000145:classification / Q000235:genetics*; D015345:Oligonucleotide Probes; D016366:Open Reading Frames; D016133:Polymerase Chain Reaction; D017386:Sequence Homology, Amino Acid
D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D015345:Oligonucleotide Probes; C433883:antigen 35, Mycobacterium avium