Destructive eyelid lesions in sarcoidosis.
OBJECTIVE
To report the clinical and histopathologic findings of a patient with sarcoidosis causing bilateral destruction of the lower eyelids.


METHODS
Case report.


RESULTS
Bilateral destructive lower eyelid lesions and cicatricial entropion developed in a 43-year-old man with systemic sarcoidosis. Histopathology was consistent with sarcoid granulomas. Disease progression was arrested with systemic prednisone and methotrexate before eyelid reconstruction was performed.


CONCLUSIONS
Sarcoidosis very rarely can cause destruction of full-thickness eyelid architecture. Active inflammation should be controlled before reconstruction.
Department of Ophthalmology, University of Cincinnati, Ohio, USA.
M
M
Moin
R C
RC
Kersten
F
F
Bernardini
D R
DR
Kulwin
D000328:Adult; D002921:Cicatrix / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D018450:Disease Progression; D004359:Drug Therapy, Combination; D004774:Entropion / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
D007166:Immunosuppressive Agents; D011241:Prednisone; D008727:Methotrexate