Serum growth hormone and insulin-like growth factor-1 concentrations in Japanese black cattle with growth retardation.
Serum concentrations of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) were determined in 5 calves in the same lineage with growth retardation. They had normal appetites, activities, body proportion, and laboratory test results. Calves with growth retardation had higher serum GH concentrations and lower serum IGF-I concentrations. These findings suggested defects in the GH-IGF-1 axis, such as in the GH-receptor.
Division of Veterinary Medicine, Faculty of Agriculture, Gifu University, Japan.
H
H
Kitagawa
K
K
Kitoh
T
T
Ito
Y
Y
Ohba
N
N
Nishii
K
K
Katoh
Y
Y
Obara
Y
Y
Motoi
Y
Y
Sasaki
D000818:Animals; D002417:Cattle / Q000097:blood / Q000235:genetics / Q000254:growth & development*; D005260:Female; D013006:Growth Hormone / Q000097:blood* / Q000235:genetics; D007334:Insulin-Like Growth Factor I / Q000235:genetics / Q000378:metabolism*; D007564:Japan; D008297:Male; D010375:Pedigree
D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone