Comparison of Roche MONITOR and Organon Teknika NucliSens assays to quantify human immunodeficiency virus type 1 RNA in cerebrospinal fluid.
We compared Roche MONITOR and Organon Teknika NucliSens assays for human immunodeficiency virus type 1 (HIV-1) RNA in cerebrospinal fluid (CSF). Results of 282 assays were highly correlated (r = 0.826), with MONITOR values being 0.29 +/- 0.4 log(10) copies/ml (mean +/- standard deviation) values. Both assays can reliably quantify HIV-1 RNA in CSF.
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. paul.spearman@mcmail.vanderbilt.edu
P
P
Spearman
S A
SA
Fiscus
R M
RM
Smith
R
R
Shepard
B
B
Johnson
J
J
Nicotera
V L
VL
Harris
L A
LA
Clough
J
J
McKinsey
D W
DW
Haas
D017088:AIDS-Related Opportunistic Infections / Q000821:virology*; D002493:Central Nervous System Diseases / Q000821:virology*; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D012367:RNA, Viral / Q000134:cerebrospinal fluid*; D011933:Reagent Kits, Diagnostic
D012367:RNA, Viral; D011933:Reagent Kits, Diagnostic