Effect of inositol on bulimia nervosa and binge eating.
OBJECTIVE
This study aimed to determine whether inositol has therapeutic value in patients with bulimia nervosa and binge eating.


METHODS
A double-blind crossover trial using 18 g inositol versus placebo was performed in 12 patients for 6 weeks in each arm.


RESULTS
Inositol was significantly better than placebo on the Global Clinical Impression, the Visual Analogue Scale, and the Eating Disorders Inventory.


CONCLUSIONS
Inositol is as therapeutic in patients with bulimia nervosa and binge eating as it is in patients with depression and panic and obsessive-compulsive disorders. This increases its parallelism with serotonin selective reuptake inhibitors.
Gelber
D
D
Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben Gurion University of the Negev, P.O. Box 4600, Beersheva, Israel.
Levine
J
J
Belmaker
R H
RH
D000328:Adult; D002032:Bulimia / Q000188:drug therapy*; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007294:Inositol / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D016896:Treatment Outcome
D007294:Inositol