Evaluation and selection of living related kidney donors--our experience in a government hospital.
In a state-funded, live related-donor kidney transplantation programme, 616 eligible end stage renal failure (ESRF) patients were seen over a four-year period. 73% of them had potential related donors, 64% of whom were willing to donate. Fear of surgery, non-congenial pre-morbid relationships and discouragement by family members were the most common reasons for unwillingness to donate. After investigations, 76% of the willing donors were found to be fit. ABO incompatibility, lymphocyte cross-match positivity and anatomic abnormalities were the most common grounds for non-acceptance. Sixty eight percent of the willing, fit donors finally donated their kidneys, patient-death and donor-recipient withdrawal before surgery accounting for the remaining. One hundred and forty eight patients underwent renal transplantation. Two-thirds of the donors were females, mothers (37%) forming the single largest group. Eight five percent of the recipients were males. Overall, only 35% of the eligible ESRF patients had related, willing and fit donors attesting to the need for an active, cadaver-donor transplantation programme.
Department of Nephrology, Madras Medical College and Government General Hospital, Madras-600 003, Tamilnadu.
M A
MA
Muthusethupathi
S
S
Rajendran
M
M
Jayakumar
R
R
Vijayakumar
D000293:Adolescent; D000328:Adult; D001294:Attitude to Health; D002648:Child; D005069:Evaluation Studies as Topic; D005195:Family Relations; D005260:Female; D006783:Hospitals, State; D006801:Humans; D007194:India; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000601:surgery*; D016031:Liver Transplantation / Q000592:standards* / Q000639:trends; D019520:Living Donors / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011446:Prospective Studies; D014019:Tissue Donors