Co-occurrence of hepatocellular carcinoma and lymphoma in patients with hepatitis C virus cirrhosis.
The association of hepatitis C virus (HCV) with neoplasia is not completely understood. Hepatitis C virus is hepatolymphotrophic. It is considered an inducing factor of hepatocellular carcinoma (HCC) and is associated with various types of lymphomas. We describe a patient with HCV cirrhosis who developed gastric lymphoma and HCC, and we review the current data and theories about the oncogenesis of HCV.
Division of Medicine, Hadassah University Hospital, Hebrew University--Hadassah Medical School, Jerusalem, Israel.
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Shapira
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Muszkat
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Braunstein
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Gotsman
D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000821:virology*; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D008113:Liver Neoplasms / Q000821:virology*; D008223:Lymphoma / Q000821:virology*; D008297:Male; D009378:Neoplasms, Multiple Primary; D013274:Stomach Neoplasms / Q000821:virology*; D020246:Venous Thrombosis / Q000150:complications