Effect of tetrapeptide cortagen on regeneration of sciatic nerve.
Intramuscular injection of 10 microg/kg cortagen to rats during 10 days after transsection and suturing of the sciatic nerve increased the growth rate and conduction velocity in the regenerating nerve fibers by 27% and 40%, respectively.
Turchaninova
L N
LN
Laboratory of General Physiology, I. P. Pavlov Institute of Physiology, Russian Academy of Science; Institute of Bioregulation and Gerontology, North-West Division of the Russian Academy of Medical Sciences, St. Petersburg.
Kolosova
L I
LI
Malinin
V V
VV
Moiseeva
A B
AB
Nozdrachev
A D
AD
Khavinson
V K
VK
D000818:Animals; D008297:Male; D009416:Nerve Regeneration / Q000187:drug effects*; D009431:Neural Conduction / Q000187:drug effects; D009842:Oligopeptides / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D012584:Sciatic Nerve / Q000187:drug effects / Q000293:injuries / Q000502:physiology
D009842:Oligopeptides; C431545:alanyl-glutamyl-aspartylprolyine