Blockade of the CD28/B7 pathway is required for the establishment of donor cell chimerism in CD40 ligand-deficient recipients.
Department of Surgery, Section of Cellular Transplantation, Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
J E
JE
Woodward
L B
LB
Zottola
A T
AT
Schaefer
A J
AJ
Logar
J K
JK
Stazer
T
T
Daskivich
R
R
Peach
A S
AS
Rao
D000069594:Abatacept; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000494:pharmacology; D016026:Bone Marrow Transplantation / Q000276:immunology*; D018106:CD28 Antigens / Q000187:drug effects* / Q000276:immunology; D023201:CD40 Ligand / Q000276:immunology*; D060908:CTLA-4 Antigen; D006086:Graft vs Host Disease; D018796:Immunoconjugates; D007166:Immunosuppressive Agents / Q000494:pharmacology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D018183:Transplantation Chimera / Q000276:immunology*
D015703:Antigens, CD; D000943:Antigens, Differentiation; D018106:CD28 Antigens; D060908:CTLA-4 Antigen; C556707:Ctla4 protein, mouse; D018796:Immunoconjugates; D007166:Immunosuppressive Agents; D023201:CD40 Ligand; D000069594:Abatacept