Efficacy of standard ten millicurie dose of radio-iodine in management of autonomously functioning toxic thyroid nodules.
Therapeutic effect of radio-iodine treatment on thyroid patients with autonomously functioning toxic thyroid nodule was evaluated. Fifty one patients were given a standard dose of 10 mci of radioiodine (I-131) and were followed up for 2-3 years. The failure rate (relapse after 10 mci of radioiodine) of this regime was 10%. It was found that the nodules less than or equal to 3 cms. in size were completely cured after a dose of 10 mic. of radio-iodine therapy, over a follow up period of next 6 months. Patients having nodules larger than 3 cms. relapsed after first dose of 10 mci of radio-iodine, but were cured completely after the second dose of 10 mci of radio-iodine therapy. Tri-iodothyronine (T3) and thyroxine (T4) values were both found to be high before giving treatment in all the cases. Only one case developed hypothyroidism after radioiodine therapy.
Inst. of Nuclear Medicine and Allied Sciences, New Delhi.
R
R
Sharma
A
A
Bhatnagar
A
A
Mondal
R
R
Kashyap
C M
CM
Khanna
D005260:Female; D005500:Follow-Up Studies; D006044:Goiter, Nodular / Q000150:complications / Q000532:radiotherapy*; D006801:Humans; D006980:Hyperthyroidism / Q000209:etiology / Q000532:radiotherapy*; D007457:Iodine Radioisotopes / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D016896:Treatment Outcome
D007457:Iodine Radioisotopes