Cadherins in embryonic and neural morphogenesis.
Cadherins not only maintain the structural integrity of cells and tissues but also control a wide array of cellular behaviours. They are instrumental for cell and tissue polarization, and they regulate cell movements such as cell sorting, cell migration and cell rearrangements. Cadherins may also contribute to neurite outgrowth and pathfinding, and to synaptic specificity and modulation in the central nervous system.
Department of Zoology, University of Toronto, 25 Harbord Street, Toronto, Ontario M5S 3G5, Canada. utepass@zoo.utoronto.ca
U
U
Tepass
K
K
Truong
D
D
Godt
M
M
Ikura
M
M
Peifer
D000595:Amino Acid Sequence; D000818:Animals; D015820:Cadherins / Q000235:genetics / Q000502:physiology*; D002448:Cell Adhesion; D002490:Central Nervous System / Q000196:embryology / Q000502:physiology*; D005314:Embryonic and Fetal Development; D006801:Humans; D008969:Molecular Sequence Data; D009024:Morphogenesis; D009420:Nervous System / Q000166:cytology / Q000196:embryology*; D017433:Protein Structure, Secondary; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D013569:Synapses / Q000502:physiology
D015820:Cadherins