Clinical outcome and diseases associated with extreme neutrophilic leukocytosis in cats: 104 cases (1991-1999).
OBJECTIVE
To describe diseases, prognosis, and clinical outcomes associated with extreme neutrophilic leukocytosis in cats.


METHODS
Retrospective study.


METHODS
104 cats with extreme neutrophilic leukocytosis.


METHODS
Medical records from 1991 to 1999 were examined to identify cats that had > or =50,000 WBC/microl with > or =50% neutrophils. Signalment, absolute and differential WBC counts, rectal temperature, clinical or pathologic diagnosis, duration and cost of hospitalization, and survival time were reviewed.


RESULTS
Mean age of cats was 8.3 years, mean WBC count was 73,055 cells/microl, and mean absolute neutrophil count was 59,046 cells/microl. Mean duration of hospitalization was 5.9 days, and mean cost of hospitalization was $2,010. Twenty-nine (28%) cats were febrile, and 63 (61%) cats died. Overall median survival time was 30 days. Cats with neoplasia were nearly 14 times as likely to die unexpectedly as cats with other diseases.


CONCLUSIONS
Extreme neutrophilic leukocytosis was associated with a high mortality rate. The prognostic importance of extreme neutrophilic leukocytosis should not be overlooked. Cats and dogs have similar diseases, mortality rates, and treatment costs associated with extreme neutrophilic leukocytosis.
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616, USA.
M D
MD
Lucroy
B R
BR
Madewell
D000818:Animals; D002371:Cat Diseases / Q000401:mortality* / Q000628:therapy; D002415:Cats; D005260:Female; D006760:Hospitalization / Q000191:economics; D006762:Hospitals, Animal; D007154:Immune System Diseases / Q000662:veterinary; D007902:Length of Stay; D007958:Leukocyte Count / Q000662:veterinary; D007964:Leukocytosis / Q000401:mortality / Q000628:therapy / Q000662:veterinary*; D008297:Male; D009369:Neoplasms / Q000150:complications / Q000662:veterinary; D009504:Neutrophils / Q000473:pathology*; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis; D013997:Time Factors