title: Methods for obtaining and analyzing unattended polysomnography data for a multicenter study. Sleep Heart Health Research Group.
abstract: This paper reviews the data collection, processing, and analysis approaches developed to obtain comprehensive unattended polysomnographic data for the Sleep Heart Health Study, a multicenter study of the cardiovascular consequences of sleep-disordered breathing. Protocols were developed and implemented to standardize in-home data collection procedures and to perform centralized sleep scoring. Of 7027 studies performed on 6697 participants, 5534 studies were determined to be technically acceptable (failure rate 5.3%). Quality grades varied over time, reflecting the influences of variable technician experience, and equipment aging and modifications. Eighty-seven percent of studies were judged to be of "good" quality or better, and 75% were judged to be of sufficient quality to provide reliable sleep staging and arousal data. Poor submental EMG (electromyogram) accounted for the largest proportion of poor signal grades (9% of studies had <2 hours artifact free EMG signal). These data suggest that with rigorous training and clear protocols for data collection and processing, good-quality multichannel polysomnography data can be obtained for a majority of unattended studies performed in a research setting. Data most susceptible to poor signal quality are sleep staging and arousal data that require clear EEG (electroencephalograph) and EMG signals.
authors: Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA. sxr15@po.cwru.edu
authors: S
authors: S
authors: Redline
authors: M H
authors: MH
authors: Sanders
authors: B K
authors: BK
authors: Lind
authors: S F
authors: SF
authors: Quan
authors: C
authors: C
authors: Iber
authors: D J
authors: DJ
authors: Gottlieb
authors: W H
authors: WH
authors: Bonekat
authors: D M
authors: DM
authors: Rapoport
authors: P L
authors: PL
authors: Smith
authors: J P
authors: JP
authors: Kiley
mesh_terms: D004569:Electroencephalography; D004576:Electromyography; D005240:Feasibility Studies; D006801:Humans; D008004:Licensure; D017286:Polysomnography / Q000379:methods*; D012107:Research Design / Q000592:standards; D012891:Sleep Apnea Syndromes / Q000175:diagnosis* / Q000453:epidemiology; D013663:Teaching / Q000592:standards