Allergic contact dermatitis from 3-iodo-2-propynyl-butylcarbamate (IPBC) - an update.
Results from 3 1/2 years of routine patch testing with 3-iodo-2-propynyl-butylcarbamate (IPBC) are presented. From 1996 to 1999, a total of 3168 persons (2093 women and 1075 men) were patch tested with IPBC, and 7 cases were found to be positive. In 2 cases, sensitization could be attributed to cosmetics, and in a further 2 cases cosmetics were the most likely cause of sensitisation. It is concluded that the use of IPBC in cosmetic products can lead to contact sensitization and allergic contact dermatitis. 2 of the 7 reported cases with IPBC allergy were also found positive to thiuram, and possible cross-reactivity between IPBC and thiuram is discussed.
Bryld
L E
LE
Department of Dermatology, Gentofte University Hospital, 2900 Hellerup, Denmark.
Agner
T
T
Menné
T
T
D000485:Allergens / Q000009:adverse effects*; D002219:Carbamates / Q000009:adverse effects*; D003358:Cosmetics / Q000009:adverse effects; D003429:Cross Reactions; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D010328:Patch Tests; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects*; D013893:Thiram / Q000009:adverse effects
D000485:Allergens; D002219:Carbamates; D003358:Cosmetics; D011310:Preservatives, Pharmaceutical; D013893:Thiram; C106572:3-iodo-2-propynylbutylcarbamate