The levels of tetrodotoxin and its analogue 6-epitetrodotoxin in the red-spotted newt, Notophthalmus viridescens.
Tetrodotoxin (TTX) and its analogue 6-epiTTX were detected in 11-12 specimens of the red-spotted newt, Notophthalmus viridescens, by a post-column fluorescent-HPLC system and by LC/MS in selected ion monitoring mode. TTX levels varied considerably among individuals from low (less than 0.15 microg TTX/g newt) to high concentrations (23.5 microg TTX/g newt), while 6-epiTTX was found to be a minor constituent in all specimens.
Yotsu-Yamashita
M
M
Graduate School of Agricultural Science, Tohoku University, 1-1 Tsutsumidori-Amamiyamachi, Aoba-ku, 981-8555, Sendai, Japan.
Mebs
D
D
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D009673:Notophthalmus viridescens / Q000378:metabolism*; D013779:Tetrodotoxin / Q000032:analysis*
C076431:6-epitetrodotoxin; D013779:Tetrodotoxin