Functional anatomy: from molecule to memory.
The Drosophila memory gene amnesiac is expressed in neurons that project to mushroom body axons. Blockade of synaptic transmission in the amnesiac-expressing cells disrupts memory, but not learning, suggesting presynaptic and postsynaptic sites for memory formation.
Dubnau
J
J
Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Tully
T
T
D000818:Animals; D004330:Drosophila; D029721:Drosophila Proteins; D034281:Dynamins; D020558:GTP Phosphohydrolases / Q000235:genetics / Q000502:physiology; D007858:Learning / Q000502:physiology; D008568:Memory / Q000502:physiology*; D009474:Neurons; D009479:Neuropeptides / Q000235:genetics / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*
D029721:Drosophila Proteins; D009479:Neuropeptides; C093565:amn protein, Drosophila; D020558:GTP Phosphohydrolases; D034281:Dynamins