title: Spontaneous rupture of mediastinal cystic teratoma into the pleural cavity: report of two cases and review of the literature.
abstract: The authors report on two female patients aged 12 and 14 years, who spontaneously developed a rupture of benign mediastinal cystic teratoma into the right pleural cavity. They presented with acute onset of severe chest pain and respiratory distress. The tumors were completely resected by thoracotomy. The serum and pleural fluid levels of carcinoembryonic antigens, CA-125 and CA19-9 were invariably elevated, then decreased to normal range after the surgical resection. Rapid diagnosis of this extremely rare complication is important because it may progress to a life-threatening condition.
authors: Department of Pediatrics, Nishi-Kobe Medical Center, 5-7-1 Kojidai, Nishi-ku, Kobe 651-2273,  Japan. kskmatsu@portnet.ne.jp
authors: K
authors: K
authors: Matsubara
authors: M
authors: M
authors: Aoki
authors: N
authors: N
authors: Okumura
authors: T
authors: T
authors: Menju
authors: H
authors: H
authors: Nigami
authors: H
authors: H
authors: Harigaya
authors: K
authors: K
authors: Baba
mesh_terms: D000293:Adolescent; D018394:CA-125 Antigen / Q000032:analysis / Q000097:blood; D018395:CA-19-9 Antigen / Q000032:analysis / Q000097:blood; D002272:Carcinoembryonic Antigen / Q000032:analysis / Q000097:blood; D002648:Child; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D010994:Pleura; D010996:Pleural Effusion / Q000737:chemistry; D011859:Radiography; D012422:Rupture, Spontaneous; D013724:Teratoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery
chemical_list: D018394:CA-125 Antigen; D018395:CA-19-9 Antigen; D002272:Carcinoembryonic Antigen