title: Cascade filtration (CF) with the Haemonetics MCS+: a new technical adaptation.
abstract: CF was introduced in clinical medicine in 1980. Up to now, exclusively two-vein procedures have been carried out with some limitations to expansion of this technique. In this report we describe the very first application of single-needle CF carried out with Haemonetics MCS + apparatus. Twenty procedures were completed without any untoward effect in patients suffering from TTP, post-hepatitic cryoblobulinemia, familial hypercholesterolemia and acute Guillan-Barrè Syndrome. From 1 to 4 sessions were carried out per patient with the expected laboratory and clinical results. The only limit is the procedure time that averages 231 +/- 48 min., approximately 40% longer than two needle procedures.
authors: Immunohaematology Services, San Martino University Hospital, Genova -Italy. maurovalbonesi@smartino.ge.it
authors: M
authors: M
authors: Valbonesi
authors: A
authors: A
authors: Bo
authors: M C
authors: MC
authors: De Luigi
authors: R
authors: R
authors: Bruni
authors: P
authors: P
authors: Stura
authors: B
authors: B
authors: Sanfilippo
authors: I
authors: I
authors: Varinelli
mesh_terms: D003449:Cryoglobulinemia / Q000628:therapy; D004867:Equipment Design; D005260:Female; D005374:Filtration; D020275:Guillain-Barre Syndrome / Q000628:therapy; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis / Q000295:instrumentation / Q000379:methods*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000628:therapy; D016896:Treatment Outcome