Aluminum-controlled reactivity and diastereoselectivity toward radical reactions of optically active aldimines with metallic samarium.
The intermolecular pinacol-type coupling reaction and allylation reaction of optically active imines bearing a beta-hydroxy group were performed stereoselectively with metallic samarium after treatment of the imines with trimethylaluminum.
Yanada
R
R
Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan. ryanada@pharm.kyoto-u.ac.jp
Okaniwa
M
M
Kaieda
A
A
Ibuka
T
T
Takemoto
Y
Y