title: A selenide linker for "traceless" solid-phase organic synthesis.
abstract: 4-Bromophenethyl alcohol was protected as the THP ether, followed by reaction with magnesium and selenium to give the corresponding diselenide. Ether deprotection provides a diselenide diol, which is attached to solid-phase resins. The polymer-bound selenide anion is then generated, and functions as a traceless linker for electrophiles such as alkyl halides.
authors: Institute of Molecular and Cell Biology, National University of Singapore, 30 Medical Drive, Singapore 117609, Singapore.
authors: Z
authors: Z
authors: Li
authors: B A
authors: BA
authors: Kulkarni
authors: A
authors: A
authors: Ganesan
mesh_terms: D009930:Organic Chemicals / Q000138:chemical synthesis*; D018036:Selenium Compounds / Q000737:chemistry*
chemical_list: D009930:Organic Chemicals; D018036:Selenium Compounds