title: Pneumocystis carinii pneumonia in a Cavalier King Charles Spaniel.
abstract: Pneumocystis carinii pneumonia was diagnosed by postmortem examination of a one-year-old Cavalier King Charles Spaniel with four-week history of dyspnea. Cytologic and histologic examination of lung tissues revealed numerous P. carinii trophozoites and cysts, and P. carinii specific DNA was detected by polymerase chain reaction. The dog showed hypogammagloblinemia and extremely low levels of serum IgG. It was considered that P. carinii pneumonia in this case was associated with an immunodeficient condition which has already been reported in Miniature Dachshunds.
authors: Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Science, The University of Tokyo, Japan.
authors: Y
authors: Y
authors: Hagiwara
authors: S
authors: S
authors: Fujiwara
authors: H
authors: H
authors: Takai
authors: K
authors: K
authors: Ohno
authors: K
authors: K
authors: Masuda
authors: T
authors: T
authors: Furuta
authors: H
authors: H
authors: Nakayama
authors: K
authors: K
authors: Doi
authors: H
authors: H
authors: Tsujimoto
mesh_terms: D000818:Animals; D004271:DNA, Fungal / Q000737:chemistry / Q000302:isolation & purification; D004283:Dog Diseases / Q000175:diagnosis / Q000382:microbiology*; D004285:Dogs; D004417:Dyspnea / Q000662:veterinary; D017809:Fatal Outcome; D008297:Male; D011010:Pneumocystis / Q000235:genetics / Q000302:isolation & purification*; D011020:Pneumonia, Pneumocystis / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D016133:Polymerase Chain Reaction / Q000662:veterinary
chemical_list: D004271:DNA, Fungal