Longitudinal study of blood pressure and stroke in over 37,000 People in China.
As part of a longitudinal study performed in urban China, 37,655 subjects were evaluated for stroke risk factors, including having their blood pressure measured in a standard fashion. The cohort was followed for 3.5 years during which time 427 subjects experienced incident strokes--221 ischemic, 203 hemorrhagic, and 3 undefined. Both systolic and diastolic blood pressure were significantly related to risk of stroke and stroke type. Associations were stronger for systolic than diastolic blood pressure. These results emphasize the importance of systolic blood pressure, as opposed to diastolic, as a risk factor for stroke. In this study, the risk of stroke is increased by about 25% with each 10 mm Hg increase in systolic blood pressure.
Fang
X H
XH
Department of Neuroepidemiology, Beijing Neurosurgical Institute, Beijing, People's Republic of China.
Longstreth
W T
WT
Li
S C
SC
Kronmal
R A
RA
Cheng
X M
XM
Wang
W Z
WZ
Wu
S
S
Du
X L
XL
Dai
X Y
XY
D000328:Adult; D000428:Alcohol Drinking; D044466:Asian People; D001794:Blood Pressure; D015992:Body Mass Index; D002545:Brain Ischemia / Q000453:epidemiology; D002543:Cerebral Hemorrhage / Q000453:epidemiology; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D003710:Demography; D003920:Diabetes Mellitus / Q000453:epidemiology; D003971:Diastole; D005260:Female; D006331:Heart Diseases / Q000453:epidemiology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D012306:Risk; D012907:Smoking; D020521:Stroke / Q000453:epidemiology* / Q000503:physiopathology / Q000517:prevention & control; D013599:Systole; D014505:Urban Population