title: Linear IgA bullous dermatosis in a patient with renal cell carcinoma.
abstract: Linear IgA bullous dermatosis (LABD) is an autoimmune subepidermal bullous disease with heterogeneous clinical manifestations, characterized by linear deposition of IgA along the epidermal basement membrane zone. We report a patient with a metastasized renal cell carcinoma who developed an extensive blistering eruption. The lesions showed immunopathological findings characteristic of LABD. The patient showed a fair response to prednisolone and dapsone. Treatment to control the LABD was no longer required when interferon-alfa was started as palliative therapy for the metastasized renal cell carcinoma. The association of LABD and malignancies has been documented before and is not due to mere chance alone.
authors: Department of Dermatology, University Hospital Vrije Universiteit, PO Box 7057, 1007 MB Amsterdam, The Netherlands. rif.vdwaal@azvu.nl
authors: R I
authors: RI
authors: van der Waal
authors: M R
authors: MR
authors: van de Scheur
authors: H H
authors: HH
authors: Pas
authors: M F
authors: MF
authors: Jonkman
authors: C J
authors: CJ
authors: Van Groeningen
authors: C
authors: C
authors: Nieboer
authors: T M
authors: TM
authors: Starink
mesh_terms: D001327:Autoimmune Diseases / Q000209:etiology; D002292:Carcinoma, Renal Cell / Q000150:complications*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007680:Kidney Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D012872:Skin Diseases, Vesiculobullous / Q000209:etiology*
chemical_list: D007070:Immunoglobulin A