title: Pulpal evaluation of two adhesive systems in rat teeth.
abstract: Formocresol is the agent most frequently used with pulpotomies in primary teeth, but its use is currently under discussion in regard to its possible toxic effects. Some current works suggest the use of dentinal adhesives in cavities with minimal dentinal thickness and even in small pulpal exposures. Our objective was to evaluate pulpal response to the application of two dentinal adhesives Syntac and Prime & Bond NT in pulpal exposures in rat teeth. Sprague Dawley rats were used, male, 150 to 200 gm in weight. The maxillary first molar, left and right, was employed in each case, a total of twelve teeth. Duration of the study was 45 days. Sections were evaluated using a light microscope in order to determine pulpal response to the two adhesives. In both groups the persistence of chronic inflammation was associated with the absence of dentinal bridges in the affected specimens. Areas of necrosis and absence of regularity of the odontoblastic layer could also be seen.
authors: Dental School, University of Murcia, Spain.
authors: O
authors: O
authors: Cortés
authors: C
authors: C
authors: García
authors: A
authors: A
authors: Bernabé
mesh_terms: D000818:Animals; D017438:Bisphenol A-Glycidyl Methacrylate / Q000627:therapeutic use; D003737:Dental Cavity Preparation; D003782:Dental Pulp / Q000187:drug effects* / Q000473:pathology; D003785:Dental Pulp Capping; D003789:Dental Pulp Exposure / Q000628:therapy*; D003790:Dental Pulp Necrosis / Q000145:classification / Q000473:pathology; D003809:Dentin, Secondary / Q000473:pathology; D017220:Dentin-Bonding Agents / Q000627:therapeutic use*; D005500:Follow-Up Studies; D008297:Male; D008963:Molar; D009804:Odontoblasts / Q000187:drug effects / Q000473:pathology; D011109:Polymethacrylic Acids / Q000627:therapeutic use; D011671:Pulpitis / Q000145:classification / Q000473:pathology; D011672:Pulpotomy; D051381:Rats; D017207:Rats, Sprague-Dawley; D019279:Resin Cements / Q000627:therapeutic use
chemical_list: D017220:Dentin-Bonding Agents; D011109:Polymethacrylic Acids; C103500:Prime & Bond; D019279:Resin Cements; C078484:Syntac dentine adhesive; D017438:Bisphenol A-Glycidyl Methacrylate