title: Management of brain stem abscess.
abstract: The brain stem is an uncommon site of a brain abscess. Such lesions were invariably fatal before 1974, when the arrival of computed tomography and magnetic resonance imaging improved the prognosis. This new case with a good result shows the usefulness of early diagnosis, careful clinical and radiological monitoring and combined medical and surgical management. A child 2 1/2 years of age was admitted to the department of neurosurgery for diagnosis and treatment of a brain stem lesion. The clinical context and discovery of an intrabronchial foreign body, as well as neuroradiological investigations, suggested a diagnosis of brain stem abscess. Initial treatment with broad spectrum antibiotics with good cerebral penetration was associated with an increase in the size of the abscess and clinical worsening. Stereotactic aspiration of lesion was performed by a transpeduncular approach under CT guidance and general anaesthesia. Secondary thoracotomy enabled removal of an intrabronchial needle. After evacuation, in spite of failure to identify the organism, neurological deficit resolved rapidly and the lesion no longer appeared on CT. Management of a brain abscess always includes antibiotics. They must cover the organisms most often encountered in brain abscesses and have good cerebral penetration. Medical treatment seems to suffice for small abscesses. A brain stem abscess with rapid clinical signs, together with current neuroradiogical diagnostic techniques, enables early discovery of such abscesses when they are still small. Treatment of brain stem abscesses includes primary antibiotic therapy, then stereotaxic drainage when there is any diagnostic doubt, poor clinical tolerability or antibiotic resistance.
authors: Department of Pediatric Neurosurgery, La Timone, Marseille, France.
authors: S
authors: S
authors: Fuentes
authors: P
authors: P
authors: Bouillot
authors: J
authors: J
authors: Regis
authors: G
authors: G
authors: Lena
authors: M
authors: M
authors: Choux
mesh_terms: D000658:Amoxicillin / Q000627:therapeutic use; D001922:Brain Abscess / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D001933:Brain Stem; D001980:Bronchi; D002439:Cefotaxime / Q000627:therapeutic use; D002675:Child, Preschool; D004322:Drainage / Q000379:methods; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005260:Female; D005547:Foreign Bodies / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
chemical_list: D008795:Metronidazole; D000658:Amoxicillin; D002439:Cefotaxime