title: AtMYB4: a transcription factor general in the battle against UV.
abstract: Mounting evidence indicates that members of the large family of plant MYB proteins are involved in the transcriptional regulation of an array of metabolic and developmental processes. Recently, the Arabidopsis thaliana MYB, AtMYB4, was shown to regulate the accumulation of the UV-protectant compound sinapoylmalate by repressing the transcription of the gene encoding the phenylpropanoid enzyme cinnamate 4-hydroxylase. AtMYB4 is thus a key regulator of phenylpropanoid pathway gene expression, and is the first example of a MYB protein that functions as a transcriptional repressor.
authors: Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA.
authors: M R
authors: MR
authors: Hemm
authors: K M
authors: KM
authors: Herrmann
authors: C
authors: C
authors: Chapple
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000378:metabolism; D029681:Arabidopsis Proteins; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000378:metabolism; D015536:Down-Regulation; D018506:Gene Expression Regulation, Plant; D008293:Malates / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism; D010666:Phenylpropionates / Q000378:metabolism; D010940:Plant Proteins / Q000235:genetics* / Q000378:metabolism; D020598:Proto-Oncogene Proteins c-myb; D050564:Trans-Cinnamate 4-Monooxygenase; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism; D014466:Ultraviolet Rays
chemical_list: C079164:2-O-sinapoylmalate; C511988:ATR1 protein, Arabidopsis; D029681:Arabidopsis Proteins; C511989:CPC protein, Arabidopsis; C493362:CYP73A5 protein, Arabidopsis; D004268:DNA-Binding Proteins; D008293:Malates; D010666:Phenylpropionates; D010940:Plant Proteins; D020598:Proto-Oncogene Proteins c-myb; D014157:Transcription Factors; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D050564:Trans-Cinnamate 4-Monooxygenase