title: Epidemiological profile of malaria in a university hospital in the eastern region of Saudi Arabia.
abstract: OBJECTIVE
  To study the epidemiological, clinical and hematological profile of laboratory-diagnosed malaria cases at King Fahd Hospital of the University, Al-Khobar, Saudi Arabia, during the period from January 1990 to December 1999, and to provide suitable recommendations accordingly.
  
  
  METHODS
  This was a clinical case series study of confirmed cases presenting to King Fahd Hospital of the University during the period from January 1990 to December 1999. A specially designed form was used for data collection and 602, laboratory-confirmed cases of malaria were retrospectively analyzed.
  
  
  RESULTS
  There were 602 cases with a mean age of 25.8 + 14.3 and a male to female ratio of 2.9:1. Less than half the cases were Saudis (42%), most of whom (93%) reported a history of travel to the Southwestern part of the Kingdom. The highest frequency of cases was observed in the years 1992, 1994 and 1998 and 40% of the cases were diagnosed during the months of February, March and September. Plasmodium falciparum was the most common species among Saudi (83%), Sudanese (72%) and Yemeni (64%) patients, while Plasmodium vivax was predominant among others. Most of these cases (75%) had a history of travel to their home countries (endemic areas). The most common clinical presentation was fever (97%), while the most common clinical signs were splenomegaly (9%) and jaundice (8%). Anemia (60%) and thrombocytopenia (53%) were the most common hematological findings.
  
  
  CONCLUSIONS
  Although it appears that the Eastern Province is still free of indigenous malaria transmission, this could not be confirmed by the data. Imported cases, however represent a continuous threat due to the existence of such vectors as Anopheles stephensi, Anopheles fluviatilis, Anopheles sergentii and Anopheles superpictus and a large number of non-immune persons. It is recommended that malaria be always considered in the differential diagnosis of all acute fevers, especially among those with a history of travel to an endemic area. Prompt diagnosis and treatment is necessary. Chemoprophylaxis, when traveling to endemic areas is mandatory, as well as the use of other primary preventive measures to protect against mosquito bites.
authors: Department of Medical Laboratory, College of Medicine, King Faisal University, Dammam, Kingdom of Saudi Arabia.
authors: L A
authors: LA
authors: Bashwari
authors: A M
authors: AM
authors: Mandil
authors: A A
authors: AA
authors: Bahnassy
authors: M A
authors: MA
authors: Al-Shamsi
authors: H A
authors: HA
authors: Bukhari
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D019353:Endemic Diseases; D005260:Female; D006785:Hospitals, University; D006801:Humans; D008288:Malaria / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D012529:Saudi Arabia / Q000453:epidemiology