Ciprofloxacin-induced acute renal failure in a patient with cystic fibrosis.
Acute renal failure is a rare adverse reaction of antibiotic therapy with quinolones seldom seen in young patients. We report an 18-year-old young woman with cystic fibrosis who experienced a pronounced decline in renal function after oral treatment with ciprofloxacin for 3 weeks. Withdrawal of the drug led to normalization of renal function after 10 days.
Bald
M
M
University Children's Hospital, University of Essen, Germany.
Ratjen
F
F
Nikolaizik
W
W
Wingen
A M
AM
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000293:Adolescent; D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D003404:Creatinine / Q000097:blood; D003550:Cystic Fibrosis / Q000150:complications; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000188:drug therapy; D011552:Pseudomonas Infections / Q000188:drug therapy
D000890:Anti-Infective Agents; D002939:Ciprofloxacin; D003404:Creatinine