title: In vitro cultivation and characterization of axenic amastigotes of Leishmania.
abstract: The establishment of axenic cultures of the amastigote stage of Leishmania is important to understand the mechanisms regulating the differentiation, survival and pathogenicity of the parasite with a view to develop and identify molecular and chemotherapeutic targets. Recent developments in axenic culture and the characterization of amastigotes of different species of Leishmania are discussed.
authors: Division of Biochemistry, Central Drug Research Institute, -226001, Lucknow, India
authors: N
authors: N
authors: Gupta
authors: N
authors: N
authors: Goyal
authors: A K
authors: AK
authors: Rastogi
mesh_terms: D000818:Animals; D000953:Antigens, Protozoan / Q000032:analysis; D000954:Antigens, Surface / Q000032:analysis; D003470:Culture Media; D017125:Genes, Protozoan; D007891:Leishmania / Q000254:growth & development* / Q000472:pathogenicity / Q000502:physiology / Q000648:ultrastructure; D021261:Parasitic Sensitivity Tests; D010274:Parasitology / Q000379:methods; D015800:Protozoan Proteins / Q000378:metabolism; D014774:Virulence
chemical_list: D000953:Antigens, Protozoan; D000954:Antigens, Surface; D003470:Culture Media; D015800:Protozoan Proteins