Peter Satir -- investigating the structural basis for cell function.
Peter Satir has devoted his research career to elucidating the structural basis for ciliary motility. His ingenious use of structural analysis, combined with identification of powerful model systems, provided a model for the sliding microtubule hypothesis of ciliary bending and led to the discovery that dynein is a 'minus-end'-directed motor whose regulated activity underpins the bending motion of cilia. Here, we focus on ciliary motility to illustrate Satir's pioneering contributions to cell biology.
Sale
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Dept of Cell Biology, Emory University School of Medicine, 1648 Pierce Drive, Atlanta, GA 30322, USA. win@cellbio.emory.edu
Barkalow
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D000818:Animals; D002468:Cell Physiological Phenomena; D002923:Cilia / Q000502:physiology*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D009518:New York; D012106:Research / Q000266:history