Successful management of polyneuropathy associated with IgM gammopathy of undetermined significance with antibody-based immunoadsorption.
Peripheral polyneuropathies associated with monoclonal IgM gammopathy of undetermined significance often have a progressive course and optimal treatment has not been established. We report on a patient diagnosed with polyneuropathy associated with benign IgM gammopathy, who was successfully treated with antibody-based immunoadsorption only. The neurological symptoms of the patient improved continuously over six months of treatment. Controlled trials should be performed to define this indication for antibody-based immunoadsorption therapy.
Toepfer
M
M
Division of Nephrology, Medizinische Klinik, Ludwig-Maximilians-Universität, München, Germany.
Schroeder
M
M
Müller-Felber
W
W
Lochmüller
H
H
Sitter
T
T
Pongratz
D
D
Schiffl
H
H
D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology*; D007163:Immunosorbent Techniques; D008297:Male; D008875:Middle Aged; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000150:complications* / Q000276:immunology; D011115:Polyneuropathies / Q000276:immunology / Q000628:therapy*; D013997:Time Factors
D007075:Immunoglobulin M