[Vinyl chloride and 1,2-dichloroethane: classification and assessment of carcinogenicity, guidelines, threshold values, and standards developed by national and international entities, organizations, and agencies].
International, national and regulatory classification, evaluation, guidelines and occupational exposure values regarding vinyl chloride and 1,2-dichloroethane, carried out by European Union (EU). Environmental Protection Agency (US EPA), International Agency for Research on Cancer (IARC), Italian National Advisory Toxicological Committee (CCTN), Occupational Safety and Health Administration (OSHA), World Health Organization (WHO), National Institute for Occupational Safety and Health (NIOSH), American Conference of Governmental Industrial Hygienists (ACGIH) and other institutions, have been considered with particular reference to the carcinogenic effects. Moreover information is reported in support of classification and evaluation and a short historical review since early 1970s, when first evidence that occupational exposure to VC could lead to angiosarcoma was published.
Binetti
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Istituto superiore di sanità, Laboratorio di tossicologia applicata, Inventario nazionale delle sostanze chimiche, Roma. binetti@iss.it
Costamagna
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FM
Marcello
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D002273:Carcinogens; D005025:Ethylene Dichlorides; D006801:Humans; D007390:International Agencies; D008452:Maximum Allowable Concentration; D016273:Occupational Exposure; D014752:Vinyl Chloride
D002273:Carcinogens; D005025:Ethylene Dichlorides; C024565:ethylene dichloride; D014752:Vinyl Chloride