[Progress in researches on anti-tumor agent L-asparaginase for treatment of leukemia].
L-asparaginase is a very effective anti-tumor agent. To take the most advantage of enzyme treatment method, the natural L-asparaginase could be chemically modified, entrapped or immobilized into/onto other carriers. The extracorporeal shunt system with immobilized enzyme reactor deserves to receive special attention. It provides an entirely new idea for leukemia treatment and is proved to be very prospective in the future leukemia cure.
Zhou
J
J
Chemical Engineering College, East China University of Science and Technology, Shanghai 200237.
Jin
H
H
Li
Y
Y
Jiang
T
T
D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001215:Asparaginase / Q000008:administration & dosage / Q000627:therapeutic use*; D004800:Enzymes, Immobilized / Q000627:therapeutic use; D006801:Humans; D007938:Leukemia / Q000188:drug therapy*
D000970:Antineoplastic Agents; D004800:Enzymes, Immobilized; D001215:Asparaginase