title: Six new dammarane-type triterpene saponins from the leaves of Panax ginseng.
abstract: Six new minor saponins, together with known ginsenosides, were isolated from the leaves of Panax ginseng. The new saponins were named as ginsenoside-Rh5, -Rh6, -Rh7 -Rh8, -Rh9 and -Rg7, and their structures were elucidated on the basis of chemical and physicochemical evidence to be as follows: ginsenoside-Rh5: 3beta,6alpha,12beta,24zeta-tetrahydroxy-dammar-20(22),25-diene 6-O-beta-D-glucopyranoside (1), -Rh6: 3beta,6alpha12beta,20(S)-tetrahydroxy-25-hydroperoxy-dammar-23-ene 20-O-beta-D-glucopyranoside (2), -Rh7: 3beta,7beta,12beta,20(S)-tetrahydroxy-dammar-5,24-diene 20-O-beta-D-glucopyranoside (3), -Rh8: 3beta,6alpha,20(S)-trihydroxy-dammar-24-ene-12-one 20-O-beta-D-glucopyranoside (4), -Rh9: 3beta,6alpha,20(S)-trihydroxy-12beta,23-epoxy-dammar-24-ene 20-O-beta-D-glucopyranoside (5) and -Rg7: 3-O-beta-D-glucopyranosyl 3beta,12beta,20(S),24(R)-tetrahydroxy-dammar-25-ene 20-O-beta-D-glucopyranoside (6).
authors: Shenyang Pharmaceutical University, Shenyang Pharmaceutical University, PR China.
authors: D Q
authors: DQ
authors: Dou
authors: Y J
authors: YJ
authors: Chen
authors: L H
authors: LH
authors: Liang
authors: F G
authors: FG
authors: Pang
authors: N
authors: N
authors: Shimizu
authors: T
authors: T
authors: Takeda
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D005894:Panax / Q000737:chemistry*; D010936:Plant Extracts / Q000032:analysis; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013256:Steroids / Q000737:chemistry* / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification; D000097669:Dammaranes
chemical_list: D010936:Plant Extracts; D012503:Saponins; D013256:Steroids; D014315:Triterpenes; D000097669:Dammaranes