title: Pyrrole analogues of chloramphenicol. II. Synthesis and antibacterial activity of DL-threo-1-(1-methyl-5-nitro-pyrrole-2-yl)-2-dichloroacetamidopropane-1, 3-diol.
abstract: The seven-stage synthesis of a pyrrole analogue of chloramphenicol (VII) was described. The compound exhibits a significant antibacterial activity.
authors: Department of Organic Chemistry, Institute of Chemistry, Medical Academy, 2A Mickiewicza Str., 15-230 Białystok, Poland.
authors: D
authors: D
authors: Krajewska
authors: M
authors: M
authors: Dabrowska
authors: P
authors: P
authors: Jakoniuk
authors: A
authors: A
authors: Rózański
mesh_terms: D000081:Acetamides / Q000138:chemical synthesis; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002701:Chloramphenicol / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D008826:Microbial Sensitivity Tests; D009574:Nitro Compounds / Q000138:chemical synthesis; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000081:Acetamides; D000900:Anti-Bacterial Agents; D009574:Nitro Compounds; D011758:Pyrroles; D002701:Chloramphenicol