[Cutaneous lesions and blood count changes in a 9-month old girl with glutaric aciduria type I].
Non-specific cutaneous lesions are common in patients suffering from acute myeloid leukemia (AML). Leukemic skin infiltrates are present in about 30% of cases of monoblastic or myelomonocytic leukemia. The appearance of specific skin lesions can precede bone marrow involvement. We report the case of a 9-month-old girl with acute myelogenous leukemia (FAB M5) and glutaric aciduria type I which initially presented with cutaneous lesions, anemia and leukopenia.
Landmann
E
E
Zentrum für Kinderheilkunde, Abt. für Hämatologie und Onkologie, Justus-Liebig-Universität, Giessen. Eva.Landmann@paediat.med.uni-giessen.de
Kreuder
J
J
Gortner
L
L
Neugebauer
M
M
Reiter
A
A
Blütters-Sawatzki
R
R
D000592:Amino Acid Metabolism, Inborn Errors / Q000150:complications / Q000175:diagnosis* / Q000652:urine; D000740:Anemia / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D005977:Glutarates / Q000652:urine*; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis* / Q000473:pathology; D017254:Leukemic Infiltration; D007970:Leukopenia / Q000209:etiology; D010088:Oxidoreductases / Q000172:deficiency*; D012867:Skin / Q000201:enzymology / Q000473:pathology*
D005977:Glutarates; D010088:Oxidoreductases; C042428:glutaryl coenzyme A oxidase