title: Canine hypertrophic osteoarthropathy associated with a malignant Sertoli cell tumour.
abstract: A 15-year-old crossbred dog was presented with a severe cough of acute onset and an enlarged right testis. Symptomatic treatment for presumed 'kennel cough' failed to produce any improvement and at re-examination the dog had developed a swollen right forelimb. Radiographic examination suggested a diagnosis of hypertrophic pulmonary osteoarthropathy (Marie's disease) associated with pulmonary metastases from a testicular tumour. The dog was re-presented five days later with acute-onset severe vomiting and the owner elected for euthanasia. Necropsy was performed and histopathological assessment confirmed the presence of a Sertoli cell tumour in the right testis with multiple pulmonary and renal metastases. Hypertrophic pulmonary osteoarthropathy is a rare complication of metastatic canine Sertoli cell tumour. The authors know of no previously reported cases.
authors: Fenwold Veterinary Group, Skegness, Lincolnshire.
authors: K R
authors: KR
authors: Barrand
authors: C L
authors: CL
authors: Scudamore
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D004285:Dogs; D005552:Forelimb; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D008297:Male; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000209:etiology / Q000662:veterinary*; D011859:Radiography; D012707:Sertoli Cell Tumor / Q000150:complications / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D013736:Testicular Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*