[Two elderly patients with sarcoidosis and Sjögren's syndrome].
Two elderly patients with sarcoidosis complicated with Sjögren's syndrome are described. Case 1: A 70-year-old woman was admitted due to dry eyes. Histological examination of a minor salivary gland specimen revealed lymphocytic infiltration, which was compatible with Sjögren's syndrome. Because uveitis was demonstrated, transbronchial lung biopsy (TBLB) was performed, to confirm a diagnosis of lung sarcoidosis. Histological examination of TBLB showed non-caseating granulomas compatible with sarcoidosis. Case 2: A 70-year-old woman was admitted due to dyspnea on exercise and blurred vision. Two years previously, Sjögren's syndrome was diagnosed because of a positive Shirmer test and positive SS-A antibody. Result of ophthalmic examination were compatible with uveitis. Histological examination of TBLB showed non-caseating granulomas compatible with sarcoidosis. Certain similarities between sarcoidosis and Sjögren's syndrome in terms of immunological aspects have attracted attention. In the present manuscript, a possible relationship between the two diseases as well as the characteristics of elderly sarcoidosis are discussed.
Araki
T
T
Pulmonary Division, Tokyo Metropolitan Geriatric Hospital.
Katsura
H
H
Motegi
T
T
Yamada
K
K
Uehara
T
T
Gotoh
R
R
Kida
K
K
Esaki
Y
Y
D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D017565:Sarcoidosis, Pulmonary / Q000150:complications*; D012859:Sjogren's Syndrome / Q000150:complications*