title: Successful management of polyneuropathy associated with IgM gammopathy of undetermined significance with antibody-based immunoadsorption.
abstract: Peripheral polyneuropathies associated with monoclonal IgM gammopathy of undetermined significance often have a progressive course and optimal treatment has not been established. We report on a patient diagnosed with polyneuropathy associated with benign IgM gammopathy, who was successfully treated with antibody-based immunoadsorption only. The neurological symptoms of the patient improved continuously over six months of treatment. Controlled trials should be performed to define this indication for antibody-based immunoadsorption therapy.
authors: Division of Nephrology, Medizinische Klinik, Ludwig-Maximilians-Universität, München, Germany.
authors: M
authors: M
authors: Toepfer
authors: M
authors: M
authors: Schroeder
authors: W
authors: W
authors: Müller-Felber
authors: H
authors: H
authors: Lochmüller
authors: T
authors: T
authors: Sitter
authors: D
authors: D
authors: Pongratz
authors: H
authors: H
authors: Schiffl
mesh_terms: D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology*; D007163:Immunosorbent Techniques; D008297:Male; D008875:Middle Aged; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000150:complications* / Q000276:immunology; D011115:Polyneuropathies / Q000276:immunology / Q000628:therapy*; D013997:Time Factors
chemical_list: D007075:Immunoglobulin M