title: Pulmonary sequestration: a comparison between pediatric and adult patients.
abstract: OBJECTIVE
  Modern large single institutional reports on pulmonary sequestration (PS) are extremely rare. We were interested in comparing patients with PS referred by our pediatric versus adult pulmonologists.
  
  
  METHODS
  Hospital notes of all patients operated on between 1978 and 1997 for a congenital broncho-pulmonary malformation were reviewed. In 28 patients, the parenchymal lesion was vascularized by a systemic artery and was separated from the bronchial tree, thus matching the strict definition of PS. Patient characteristics and outcome were analyzed comparing the pediatric group (< or =16 years: n=13; mean age, 3+/-5 years) versus the adult group (>16 years: n=15; mean age, 33+/-13 years).
  
  
  RESULTS
  No significant differences between both groups were observed in sex, side, type of sequestration, pulmonary venous drainage, associated anomalies, hospital and late outcome, and patient's overall score. Patients (n=21) with the intralobar type of sequestration presented significantly more often with an infection when compared with patients (n=7) with the extralobar type (91 versus 14%; P=0.0033). When compared with the pediatric group, patients in the adult group had significantly more respiratory infections (87 versus 38%; P=0.016), and also required a lobectomy more often (67 versus 31%; P=0.056).
  
  
  CONCLUSIONS
  The extralobar type of sequestration often remains asymptomatic, and is usually an incidental finding during infancy. The intralobar type mostly presents with recurrent infections in adulthood resulting in more lobectomies. We believe these findings support our current policy to remove any pulmonary malformation whenever diagnosed in order to: (1), prevent infection and other potentially serious late complications which may compromise the surgical outcome; and (2), enhance the chance of a parenchymal-sparing resection.
authors: Department of Thoracic Surgery, University Hospital Gasthuisberg, Herestraat 49, B-3000 Leuven, Belgium. dirk.vanraemdonck@uz.kuleuven.ac.be
authors: D
authors: D
authors: Van Raemdonck
authors: K
authors: K
authors: De Boeck
authors: H
authors: H
authors: Devlieger
authors: M
authors: M
authors: Demedts
authors: P
authors: P
authors: Moerman
authors: W
authors: W
authors: Coosemans
authors: G
authors: G
authors: Deneffe
authors: T
authors: T
authors: Lerut
mesh_terms: D000293:Adolescent; D000328:Adult; D001998:Bronchopulmonary Sequestration / Q000175:diagnosis / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007231:Infant, Newborn; D008875:Middle Aged; D011013:Pneumonectomy; D012189:Retrospective Studies; D016896:Treatment Outcome