CD57+ cells in radicular cyst.
OBJECTIVE
As CD57 antigen is an important modulator of the immune system, the purpose of the present study was to compare the expression of this antigen on radicular cysts (RC) with hyperplastic or atrophic epithelium.


METHODS
Twenty cases of RC were retrieved and classified as atrophic or hyperplastic. A biotin-streptavidin amplified system was used for identification of the CD57 receptor.


RESULTS
The results demonstrated a greater percentage of CD57+ cells in RC with atrophic epithelium compared to hyperplastic epithelium.


CONCLUSIONS
As the expression of CD57 is indicative of immunosuppression, it may constitute a negative immunomodulator of RC's epithelium growth. Further studies are necessary to understand the importance of this cell to the biological activity or inactivity of RC's epithelium development.
Moreira
P R
PR
Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Geris, Brazil.
Santos
D F
DF
Martins
R D
RD
Gomez
R S
RS
D018959:CD57 Antigens; D004848:Epithelium / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D018655:Lymphocyte Count; D011842:Radicular Cyst / Q000276:immunology* / Q000473:pathology*; D018709:Statistics, Nonparametric; D013601:T-Lymphocytes / Q000276:immunology
D018959:CD57 Antigens