An anti-inflammatory principle from cactus.
In previous studies, the ethanol extract of cactus (Opuntia ficus-indica) showed potent anti-inflammatory action. In the present study, following fractionation of the methanol extract of cactus stems guided by adjuvant-induced chronic inflammation model in mice, an active anti-inflammatory principle has been isolated and identified as beta-sitosterol.
Park
E H
EH
College of Pharmacy, Sookmyung Women's University, 140-742, Seoul, South Korea. parkx034@sdic.sookmyung.ac.kr
Kahng
J H
JH
Lee
S H
SH
Shin
K H
KH
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006099:Granuloma / Q000517:prevention & control*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D010946:Plants, Medicinal; D012855:Sitosterols / Q000494:pharmacology*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004365:Drugs, Chinese Herbal; D012855:Sitosterols; C025473:gamma-sitosterol