title: Assessing vascular permeability during experimental cerebral malaria by a radiolabeled monoclonal antibody technique.
abstract: Vascular endothelial integrity, assessed by Evans blue dye extrusion and radiolabeled monoclonal antibody leakage, was markedly compromised in the brain, lung, kidney, and heart during Plasmodium berghei infection, a well-recognized model for human cerebral malaria. The results for vascular permeability from both methods were significantly (P < 0.001) related.
authors: Department of Microbiology and Immunology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA. hvande@lsuhsc.edu
authors: H C
authors: HC
authors: van der Heyde
authors: P
authors: P
authors: Bauer
authors: G
authors: G
authors: Sun
authors: W L
authors: WL
authors: Chang
authors: L
authors: L
authors: Yin
authors: J
authors: J
authors: Fuseler
authors: D N
authors: DN
authors: Granger
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D002199:Capillary Permeability; D005070:Evans Blue / Q000378:metabolism; D005260:Female; D007371:Interferon-gamma / Q000502:physiology; D007457:Iodine Radioisotopes; D016779:Malaria, Cerebral / Q000503:physiopathology*; D051379:Mice; D008810:Mice, Inbred C57BL; D010962:Plasmodium berghei
chemical_list: D000911:Antibodies, Monoclonal; D007457:Iodine Radioisotopes; D005070:Evans Blue; D007371:Interferon-gamma