Bacterial cell cycle: seeing the big picture with microarrays.
Global assays of gene expression and protein stability during the Caulobacter crescentus cell cycle reveal that a surprisingly large fraction of the genome and proteome is affected as cells grow and divide. These studies are an important step toward understanding how the cell cycle is controlled in prokaryotes.
Stephens
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Biology Department, Santa Clara University, Santa Clara, California 95053, USA. cstephens@scu.edu
D001426:Bacterial Proteins / Q000378:metabolism; D016935:Caulobacter crescentus / Q000166:cytology / Q000235:genetics* / Q000254:growth & development*; D002453:Cell Cycle; D004268:DNA-Binding Proteins; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D020869:Gene Expression Profiling; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods; D020543:Proteome; D051877:RNA Polymerase Sigma 54; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000235:genetics; D012808:Sigma Factor / Q000378:metabolism; D014157:Transcription Factors
D001426:Bacterial Proteins; C097706:CtrA protein, Caulobacter; D004268:DNA-Binding Proteins; D020543:Proteome; D012808:Sigma Factor; D014157:Transcription Factors; D012321:DNA-Directed RNA Polymerases; D051877:RNA Polymerase Sigma 54