title: [Influence of intubation maneuver with or without premedication for intracranial hemorrhage with unconsciousness].
abstract: OBJECTIVE
  To clarify the influence of intubation maneuver with or without premedication for intracranial hemorrhage with unconsciousness.
  
  
  METHODS
  Between May 1995 and May 2000, we analyzed retrospectively 46 patients who had received intubation for unconsciousness and were found non-traumatic intracranial hemorrhage by head computer tomography at the Trauma and Critical Care Center, National Defense Medical College. They were divided into two groups, Drug group in which drugs were used before intubation and Control group which were intubated without drugs. Physical findings on admission, head CT findings, Glasgow Outcome Score(GOS) at discharge were analyzed between the groups.
  
  
  RESULTS
  There were no significant differences for background of subjects between the groups. In the Drug group, diazepam, pentazocine, lidocaine, nifedipine and nicardipine were used before intubation. GOS in the Control group was significantly greater than in the Drug group(p < 0.01).
  
  
  CONCLUSIONS
  In case of intubation for unconscious patients who may suffer intracranial hemorrhage, using premedication leads to favorable outcome.
authors: Departments of Traumatology and Critical Care Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
authors: Y
authors: Y
authors: Yanagawa
authors: T
authors: T
authors: Sakamoto
authors: Y
authors: Y
authors: Okada
authors: N
authors: N
authors: Tsuzuki
authors: H
authors: H
authors: Katoh
authors: H
authors: H
authors: Nawashiro
authors: K
authors: K
authors: Shima
mesh_terms: D000328:Adult; D000368:Aged; D000701:Analgesics, Opioid / Q000008:administration & dosage; D003975:Diazepam / Q000008:administration & dosage; D005260:Female; D023261:Glasgow Outcome Scale; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage; D020300:Intracranial Hemorrhages / Q000150:complications*; D007440:Intubation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010423:Pentazocine / Q000008:administration & dosage; D011292:Premedication; D012189:Retrospective Studies; D014474:Unconsciousness / Q000209:etiology*
chemical_list: D000701:Analgesics, Opioid; D006993:Hypnotics and Sedatives; D003975:Diazepam; D010423:Pentazocine