[The effect of a single moderate physical exertion on serum leptin levels in patients with essential hypertension (preliminary results)].
Leptin is a product of the ob gene and is secreted by the adipose tissue. It takes part in regulation of nervous, cardiovascular, endocrine system and renal functions. The aim of this study was to assess the influence of short term moderate exercise on serum leptin levels in patients with arterial hypertension. The study group consisted of 34 patients with essential hypertension: 15 women (48.9 +/- 12.1 years old) and 19 men (43.5 +/- 14.6 years old). There were 7 patients with stage I of hypertension, 17 patients with stage II of hypertension and 10 patients with stage III of hypertension. The blood samples were taken before and after the exercise test. Serum leptin levels were assessed by radioimmunoassay. Serum leptin levels were significantly higher in women then in men. The logarithm of serum leptin levels after the exercise was significantly lower than before (0.8 +/- 0.4 and 0.9 +/- 0.5 respectively). The moderate, short term exercise decreases serum leptin levels in the hypertensive patients.
Zyśko
D
D
Katedra i Klinika Kardiologii AM we Wrocławiu.
Gajek
J
J
Jołda-Mydłowska
B
B
D000273:Adipose Tissue / Q000378:metabolism; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D005260:Female; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000145:classification / Q000503:physiopathology*; D020738:Leptin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D012737:Sex Factors
D020738:Leptin