Viral immune evasion strategies and the underlying cell biology.
Evasion of the immune system by viruses is a well-studied field. It remains a challenge to understand how these viral tactics affect pathogenesis and the viral lifecycle. At the same time, the study of viral proteins involved in immune evasion has helped us to better understand a number of cellular processes at the molecular level. Here we review recent data on different viral tactics for immune evasion and highlight what these viral interventions might teach us about cell biology.
Lorenzo
M E
ME
Department of Pathology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
Ploegh
H L
HL
Tirabassi
R S
RS
D000818:Animals; D015536:Down-Regulation / Q000235:genetics / Q000276:immunology; D005805:Genes, MHC Class I / Q000276:immunology; D005814:Genes, Viral; D006801:Humans; D007110:Immunity, Active / Q000235:genetics; D007111:Immunity, Cellular / Q000235:genetics; D015854:Up-Regulation / Q000235:genetics / Q000276:immunology; D014764:Viral Proteins / Q000235:genetics; D015678:Viral Structural Proteins / Q000235:genetics; D014777:Virus Diseases / Q000235:genetics / Q000276:immunology* / Q000821:virology*
D014764:Viral Proteins; D015678:Viral Structural Proteins