Spatio-temporal current density reconstruction (stCDR) from EEG/MEG-data.
Among the different approaches to the bioelectromagnetic inverse problem, the current-density reconstruction methods (CDR) provide the most general solutions. Since the inverse problem does not have a unique solution, model assumptions have to be taken into account. Multi-channel measurements contain not only spatial, but also temporal information about the sources, so a naturally extension to existing methods leads to spatio-temporal model constraints. Spatio-temporal CDR's (stCDR) have been tested in simplified volume conductor models, assuming different spatial model constraints and a smooth temporal activation model. Comparison to existing spatial model constraints showed a significant improvement of spatial and temporal resolution of the reconstructed sources for the spatio-temporal models especial in noisy data.
Darvas
F
F
Department of Neurology, RWTH, Aachen, FRG.
Schmitt
U
U
Louis
A K
AK
Fuchs
M
M
Knoll
G
G
Buchner
H
H
D000465:Algorithms; D001931:Brain Mapping; D003198:Computer Simulation; D003627:Data Interpretation, Statistical; D004569:Electroencephalography / Q000706:statistics & numerical data*; D006801:Humans; D015225:Magnetoencephalography / Q000706:statistics & numerical data*; D008959:Models, Neurological