title: Influence of novel and conventional antipsychotic medication on subjective quality of life.
abstract: OBJECTIVE
  To assess the impact of novel antipsychotic medication on the subjective quality of life of patients with schizophrenia and schizoaffective disorders.
  
  
  METHODS
  Retrospective, cross-sectional analysis of data from 2 studies conducted in 1997 and 1998.
  
  
  METHODS
  91 outpatients (50 men and 41 women, mean age 43.3 years) diagnosed with schizophrenia (n = 70) and schizoaffective disorder (n = 21); the mean Global Assessment of Functioning score for these patients was 48.0 (standard deviation 12.5).
  
  
  METHODS
  Patients were categorized into 1 of 3 groups: those taking conventional (n = 41), novel (n = 26) or mixed (both conventional and novel) (n = 24) antipsychotics. Responses on the Satisfaction with Life Domains Scale were used to assess subjective quality of life.
  
  
  RESULTS
  The type of antipsychotic medication taken did not influence satisfaction with life scores; in fact, 2 items dealing with social relationships were scored lower by those taking novel antipsychotics.
  
  
  CONCLUSIONS
  Patients taking novel antipsychotics may expect more from life, and this might explain their lower quality-of-life scores.
authors: McGill University Health Centre, Montreal General Hospital, 1650 Cedar Ave., Montreal QC H3G 1A4. raymond.tempier@muhc.mcgill.ca
authors: R
authors: R
authors: Tempier
authors: N
authors: N
authors: Pawliuk
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000592:standards* / Q000627:therapeutic use*; D003430:Cross-Sectional Studies; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D010549:Personal Satisfaction; D011618:Psychotic Disorders / Q000175:diagnosis / Q000188:drug therapy*; D011788:Quality of Life; D012189:Retrospective Studies; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
chemical_list: D014150:Antipsychotic Agents