title: Translating the message.
abstract: The "one gene = one protein" model for understanding the genome is well-known. But, as with most biological "rules", it has its exceptions. The viral family that brings polio, the common cold and foot-and-mouth disease translates its entire genome into one long "polyprotein". The study of this translation strategy is bringing to light new targets for fighting disease and new techniques for the biotech industry.
authors: School of Biology, The University of St Andrews, St Andrews, Fife, KY16 9TS, Scotland, UK.
authors: G A
authors: GA
authors: Luke
authors: M D
authors: MD
authors: Ryan
mesh_terms: D006801:Humans; D010849:Picornaviridae / Q000235:genetics* / Q000502:physiology*; D014176:Protein Biosynthesis; D011499:Protein Processing, Post-Translational; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism
chemical_list: D014764:Viral Proteins