Poliomyelitis eradication: progress, challenges for the end game, and preparation for the post-eradication era.
In 1988, the World Health Assembly resolved to eradicate poliomyelitis globally by the year 2000. Dramatic progress toward this goal has occurred: three of the six WHO regions (Region of the Americas, European Region, and Western Pacific Region) are now polio free; and the number of polio-endemic countries decreased from over 125 in 1988 to 30 in 1999. Intensified efforts currently are underway to reach the target as soon as possible after 2000 in the three remaining polio-endemic WHO regions (African Region, Eastern Mediterranean Region, and South-East Asia Region). Even in polio-endemic regions, many countries are already polio free as the geographic extent of poliovirus shrinks while others. especially those experiencing conflict and war, pose substantial challenges to implementing the proven polio eradication strategies. Increasing attention and research now are devoted to the certification of polio eradication in the polio-free regions (that will include the first phase of implementing the Global Plan of Action for the laboratory containment of wild poliovirus) and formulating a policy for stopping all polio vaccination once eradication, containment, and global certification have been achieved. This report outlines the progress toward polio eradication and highlights some of the remaining issues and challenges that must be addressed before polio becomes a disease that future generations know only by history.
Sutter
R W
RW
National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Tangermann
R H
RH
Aylward
R B
RB
Cochi
S L
SL
D000349:Africa / Q000453:epidemiology; D001210:Asia, Southeastern / Q000453:epidemiology; D006801:Humans; D019083:Mediterranean Region / Q000453:epidemiology; D011051:Poliomyelitis / Q000453:epidemiology / Q000517:prevention & control*; D023321:Poliovirus Vaccines / Q000008:administration & dosage* / Q000191:economics; D011159:Population Surveillance; D014944:World Health Organization
D023321:Poliovirus Vaccines