Treatment of progressive metastatic glomus jugulare tumor (paraganglioma) with gemcitabine.
Paragangliomas are rare tumors of the paraganglia composed of specialized neural crest cells arising in association with sympathetic ganglia. Here we report a case of progressive, metastatic paraganglioma (glomus jugulare tumor) responsive to single agent gemcitabine. In addition, a brief review of chemotherapy for paraganglioma follows the case presentation.
Pipas
J M
JM
Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.
Krywicki
R F
RF
D000293:Adolescent; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology*; D003841:Deoxycytidine / Q000031:analogs & derivatives / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D010235:Paraganglioma / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary*; D014057:Tomography, X-Ray Computed; D000093542:Gemcitabine
D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000093542:Gemcitabine