P300 event-related potential decrements in well-functioning university students with mild head injury.
We compared the performance of 10 well-functioning university students who had experienced a mild head injury (MHI) an average of 6.4 years previously and 12 controls on a series of standard psychometric tests of attention, memory, and thinking and on a series of auditory oddball vigilance tasks to which we also took event-related potentials (ERPs). The MHI and Control groups performed equivalently on all the psychometric tasks and on self-report questionnaires of everyday memory and attention difficulties. The MHI group performed more slowly and with lower accuracy on only the most difficult of the oddball tasks, yet they showed substantially and significantly reduced P300 amplitudes and subsequent attentuation on all the oddball tasks, both easy and difficult. There were no alterations of N1, P2, and N2 components. These data suggest that despite excellent behavioral recovery, subtle information processing deficits involving attention nevertheless may persist long after the original injury and may not be apparent on a variety of standard psychometric measures.
Segalowitz
S J
SJ
Brock University, St. Catharines, Ontario, Canada. ssegalow@spartan.ac.brocku.ca
Bernstein
D M
DM
Lawson
S
S
D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D006259:Craniocerebral Trauma / Q000150:complications* / Q000175:diagnosis*; D004569:Electroencephalography; D004585:Electrooculography; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D006801:Humans; D008569:Memory Disorders / Q000175:diagnosis* / Q000209:etiology*; D009483:Neuropsychological Tests; D011594:Psychometrics / Q000706:statistics & numerical data; D012720:Severity of Illness Index; D013334:Students; D011795:Surveys and Questionnaires; D014495:Universities