title: Challenges with studies investigating longevity of dental restorations--a critique of a systematic review.
abstract: OBJECTIVE
  A systematic review is a method of evaluating the published and unpublished literature relating to a specific area or topic. The objectives of this paper are to identify and discuss problems encountered in synthesising the available literature; and to make recommendations for the future conduct and reporting of clinical trials that aim to determine the longevity of dental restorations.
  
  
  METHODS
  Studies were identified by a wide search of published and unpublished material in any language using a large number of general and specialist data bases, hand searching of key dental journals and searching of abstracts from conference proceedings.
  
  
  METHODS
  Pre-defined inclusion criteria based on objective outcome measures of restoration longevity and study designs were applied to determine study selection.
  
  
  CONCLUSIONS
  A review of the longevity of dental restorations completed recently encountered substantial problems in designing an appropriate protocol to address this issue. The review found that many of the factors reported previously as affecting restoration longevity could not be confirmed using the agreed systematic review protocol that incorporated an objective study design. Further, the multiplicity of study designs, and reporting methods found in the literature made meta-analyses impossible. A proforma is proposed in order to aid the design of future research into the longevity of restorations.
authors: University of Wales College of Medicine, Health Park, Cardiff CF14 4XY, UK. chadwickbl@cardiff.ac.uk
authors: B
authors: B
authors: Chadwick
authors: E
authors: E
authors: Treasure
authors: P
authors: P
authors: Dummer
authors: F
authors: F
authors: Dunstan
authors: A
authors: A
authors: Gilmour
authors: R
authors: R
authors: Jones
authors: C
authors: C
authors: Phillips
authors: J
authors: J
authors: Stevens
authors: J
authors: J
authors: Rees
authors: S
authors: S
authors: Richmond
mesh_terms: D003764:Dental Materials; D003793:Dental Restoration, Permanent; D006801:Humans; D015201:Meta-Analysis as Topic; D012107:Research Design; D016019:Survival Analysis; D013997:Time Factors; D017211:Treatment Failure; D016896:Treatment Outcome
chemical_list: D003764:Dental Materials