title: Anti-proliferative effect of two lactic acid bacteria strains of human origin on the growth of a myeloma cell line.
abstract: OBJECTIVE
  Twenty lactic acid bacteria strains were isolated from human faeces and tested by MTT assay for stimulation or inhibition of the proliferation of Vero and myeloma cells.
  
  
  RESULTS
  None of the strains significantly affected the proliferation of Vero cells. However, two isolates (HN1 and HA8) showed a strong inhibition of myeloma cell proliferation (16.7 and 5.0%, respectively) by MTT assay.
  
  
  CONCLUSIONS
  Both strains have an anti-proliferative effect on a tumoral cell line.
  
  
  CONCLUSIONS
  The beneficial effect of LAB cancer therapy has been linked to their ability for immunomodulation.
authors: Departamento de Nutrición y Bromatología III, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain.
authors: A
authors: A
authors: Zabala
authors: M R
authors: MR
authors: Martín
authors: A I
authors: AI
authors: Haza
authors: L
authors: L
authors: Fernández
authors: J M
authors: JM
authors: Rodríguez
authors: P
authors: P
authors: Morales
mesh_terms: D000276:Adjuvants, Immunologic; D000328:Adult; D000818:Animals; D000970:Antineoplastic Agents; D002273:Carcinogens / Q000494:pharmacology; D002522:Chlorocebus aethiops; D016984:Enterococcus faecium / Q000502:physiology*; D005243:Feces / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D007422:Intestines / Q000382:microbiology; D007778:Lactobacillus / Q000235:genetics / Q000502:physiology*; D051379:Mice; D019936:Probiotics / Q000627:therapeutic use*; D014407:Tumor Cells, Cultured; D014709:Vero Cells
chemical_list: D000276:Adjuvants, Immunologic; D000970:Antineoplastic Agents; D002273:Carcinogens