Indenopyrazoles as novel cyclin dependent kinase (CDK) inhibitors.
Nugiel
D A
DA
The DuPont Pharmaceuticals Company, Box 80336, Wilmington, Delaware 19880-0336, USA.
Etzkorn
A M
AM
Vidwans
A
A
Benfield
P A
PA
Boisclair
M
M
Burton
C R
CR
Cox
S
S
Czerniak
P M
PM
Doleniak
D
D
Seitz
S P
SP
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D018844:Cyclin-Dependent Kinases / Q000037:antagonists & inhibitors*; D004354:Drug Screening Assays, Antitumor; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D051379:Mice; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship; D014183:Transplantation, Heterologous; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D011720:Pyrazoles; D018844:Cyclin-Dependent Kinases