title: Oral rehydration solution containing rice maltodextrins in patients with total colectomy and high intestinal output.
abstract: Oral rehydration solutions containing rice maltodextrins (R-ORS) have been reported to be more effective than glucose-based ORS in reducing intestinal losses in infectious diarrhea. To evaluate the effect of R-ORS in patients with total colectomy and high intestinal output, a perspective open noncontrolled study was performed on 13 adult patients who consumed 1 l/day of R-ORS for 7 days. Body weight, daily ileal and urinary output, serum electrolytes, aldosterone and renin activity were measured the day before (day 0) and on the last day of the study (day 7). Net changes (mean +/- SE) from day 0-7 showed an increase of urine Na (40 +/- 16 mmol/day, p < 0.04) and K (24 +/- 8 mmol/day, p < 0.02). Body weight increased in seven patients. Serum renin activity decreased (-0.60 +/- 0.26 ng/ml/min) in these patients but not in the six patients in whom body weight remained unchanged (0.19 +/- 0.07 ng/ml/min; p < 0.03). Ileal and urinary volume remained stable. In patients with high ileal output, R-ORS supplementation improved Na and K balance. The association of increased body weight with decreased serum renin concentrations suggests that a positive water balance also occurred.
authors: First Internal Medicine Unit, Department of Internal Medicine and Gastroenterology, University of Bologna, San Orsola Hospital, Via Massarenti, 9, 40138 Bologna, Italy. pironi@med.unibo.it
authors: L
authors: L
authors: Pironi
authors: C
authors: C
authors: Guidetti
authors: E
authors: E
authors: Incasa
authors: G
authors: G
authors: Poggioli
authors: F
authors: F
authors: Paganelli
authors: C
authors: C
authors: Merli
authors: L
authors: L
authors: Fumi
authors: M
authors: M
authors: Miglioli
mesh_terms: D000328:Adult; D000368:Aged; D000450:Aldosterone / Q000097:blood; D001835:Body Weight; D002712:Chlorides / Q000032:analysis / Q000652:urine; D003082:Colectomy; D003093:Colitis, Ulcerative / Q000601:surgery; D003424:Crohn Disease / Q000601:surgery; D005243:Feces / Q000737:chemistry; D005260:Female; D005440:Fluid Therapy / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D012275:Oryza; D011134:Polysaccharides / Q000627:therapeutic use*; D011188:Potassium / Q000032:analysis / Q000652:urine; D011446:Prospective Studies; D015532:Rehydration Solutions / Q000627:therapeutic use*; D012083:Renin / Q000097:blood; D012964:Sodium / Q000032:analysis / Q000652:urine
chemical_list: D002712:Chlorides; D011134:Polysaccharides; D015532:Rehydration Solutions; D000450:Aldosterone; C008315:maltodextrin; D012964:Sodium; D012083:Renin; D011188:Potassium