title: Preliminary report: skeletal muscle cell lipid and oxygen supply.
abstract: In a group of 12 normal-weight, normotensive, nondiabetic adult females, the intramyocellular lipid (IMCL) to creatine ratio of the soleus muscle was determined using localized (1)H-magnetic resonance spectroscopy ((1)H-MRS) and related to skeletal muscle blood (and oxygen) supply (as assessed by near infrared spectroscopy [NIRS] of the forearm). A significant positive association was found between IMCL content and reoxygenation rate of forearm muscle hemoglobin (Hb) after 1 minute of ischemic exercise (r = .70, P = .01). The relative efficiency of skeletal muscle oxygen supply may be a determining factor of IMCL content in skeletal muscle.
authors: Departments of Biochemistry and Paediatrics and Child Health, The University of Sydney, Australia.
authors: J
authors: J
authors: Ward
authors: M
authors: M
authors: Ashley
authors: A
authors: A
authors: Kemp
authors: A
authors: A
authors: Buckley
authors: L A
authors: LA
authors: Baur
authors: C
authors: C
authors: Thompson
mesh_terms: D000328:Adult; D015444:Exercise / Q000502:physiology; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D050356:Lipid Metabolism; D009682:Magnetic Resonance Spectroscopy; D018482:Muscle, Skeletal / Q000166:cytology / Q000378:metabolism*; D010101:Oxygen Consumption / Q000502:physiology*; D019265:Spectroscopy, Near-Infrared