ZNF232: structure and expression analysis of a novel human C(2)H(2) zinc finger gene, member of the SCAN/LeR domain subfamily.
We have identified a novel zinc finger gene, ZNF232, mapped to human chromosome 17p12. The coding region of the gene is organized in three exons corresponding to a 417 amino acid long polypeptide containing a SCAN/LeR domain and five C(2)H(2)-type zinc fingers. ZNF232 is possibly a nuclear protein, as suggested by expression analysis of GFP/ZNF232 chimeric constructs. ZNF232 transcripts were detected in a wide collection of adult human tissues. The gene is possibly subjected to tissue-specific post-transcriptional regulation by means of alternative splicing.
Mavrogiannis
L A
LA
Department of Biology, University of Crete, P.O. Box 2208, 71409 Heraklion, Greece.
Argyrokastritis
A
A
Tzitzikas
N
N
Dermitzakis
E
E
Sarafidou
T
T
Patsalis
P C
PC
Moschonas
N K
NK
D000595:Amino Acid Sequence; D001483:Base Sequence; D002874:Chromosome Mapping; D018076:DNA, Complementary / Q000737:chemistry; D005091:Exons; D015723:Gene Library; D005796:Genes; D049452:Green Fluorescent Proteins; D006801:Humans; D017403:In Situ Hybridization; D007438:Introns; D008164:Luminescent Proteins; D008297:Male; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000235:genetics*; D014407:Tumor Cells, Cultured; D016335:Zinc Fingers
D018076:DNA, Complementary; D008164:Luminescent Proteins; D009687:Nuclear Proteins; D049452:Green Fluorescent Proteins