Atomic structures at last: the ribosome in 2000.
Last year, atomic structures of the 50S ribosomal subunit from Haloarcula marismortui and of the 30S ribosomal subunit from Thermus thermophilus were published. A year before that, a 7.8 A resolution electron density map of the 70S ribosome from T. thermophilus appeared. This information is revolutionizing our understanding of protein synthesis.
Ramakrishnan
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Medical Research Council Laboratory of Molecular Biology, Cambridge, UK. ramak@mrc-lmb.cam.ac.uk
Moore
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PB
D001665:Binding Sites; D003461:Crystallography / Q000379:methods*; D018625:Microscopy, Atomic Force; D008854:Microscopy, Electron / Q000379:methods*; D020653:Peptide Elongation Factor G / Q000737:chemistry / Q000378:metabolism; D012343:RNA, Transfer / Q000378:metabolism; D012270:Ribosomes / Q000737:chemistry* / Q000378:metabolism*
D020653:Peptide Elongation Factor G; D012343:RNA, Transfer