Catecholaminergic and acetylcholine esterase containing nerves of cranial and spinal dura mater in humans and rodents.
The innervation of cranial and spinal dura mater in humans and rodents was studied by examining several dural zones (vascular, perivascular, intervascular) in different regions. Characterization and distribution of dural acetylcholinesterase-positive nerve fibers, catecholaminergic nerve fibers, and mast cells are analyzed and discussed. The results of chemical and surgical sympathectomy as well as the relationships between catecholaminergic nerve fibers and mast cells are studied. Our results are discussed in the light of possible implications in the physiopathology of dural algic syndromes including cephalalgia and spinal pain.
Artico
M
M
Department of Pharmacology of Natural Molecules and General Physiology, Section of Anatomy, University of Rome, La Sapienza, 00185 Rome, Italy. marcoartico@uniroma1.it
Cavallotti
C
C
D000110:Acetylcholinesterase / Q000378:metabolism*; D000368:Aged; D000818:Animals; D002395:Catecholamines / Q000378:metabolism*; D002799:Cholinergic Fibers / Q000648:ultrastructure; D004388:Dura Mater / Q000098:blood supply / Q000648:ultrastructure*; D004558:Electric Stimulation; D005453:Fluorescence; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D008407:Mast Cells / Q000648:ultrastructure; D051379:Mice; D008815:Mice, Inbred Strains; D008875:Middle Aged; D009412:Nerve Fibers / Q000648:ultrastructure; D051381:Rats; D017208:Rats, Wistar; D012886:Skull / Q000098:blood supply / Q000294:innervation* / Q000648:ultrastructure; D013131:Spine / Q000098:blood supply / Q000294:innervation* / Q000648:ultrastructure
D002395:Catecholamines; D000110:Acetylcholinesterase