title: [Central necrosis of the lumbo-sacral segment of the spinal cord associated with multiple cholesterin emboli, clinically presenting as acute paraplegia].
abstract: A seventy-six-year-old man suddenly suffered from paraplegia and pain in both legs. He had been maintained on hemodialysis and committed a suicide attempt by cutting the shunt at the paraplegic attack. He was brought to the emergency ward for the treatment of hemorrhagic preshock. Neurological examination demonstrated flaccid paraplegia, loss of tendon reflex in the lower extremities, dissociated sensory loss below the fourth lumbar level; and incontinence in defecation. MRI showed T2 shortening in the ventral spinal cord caudal below the level of the eleventh thoracic cord. Postmortem examination confirmed ischemic infarct in the central area of the spinal cord, associated with disseminated cholesterin emboli in the small arteries. This case was the first MRI demonstration of central necrosis caused by cholesterin emboli, and may emphasize the significance of cholesterin emboli in the spinal arterial disorders in the aged.
authors: Department of Neurology, Showa General Hospital.
authors: M
authors: M
authors: Yoshimura
authors: M
authors: M
authors: Uchigata
authors: S
authors: S
authors: Shimizu
authors: T
authors: T
authors: Sakamoto
authors: S
authors: S
authors: Murayama
mesh_terms: D000208:Acute Disease; D000368:Aged; D001161:Arteriosclerosis / Q000150:complications; D017700:Embolism, Cholesterol / Q000150:complications*; D017809:Fatal Outcome; D006801:Humans; D007238:Infarction / Q000209:etiology; D008161:Lumbosacral Region; D008297:Male; D009336:Necrosis; D010264:Paraplegia / Q000209:etiology*; D013116:Spinal Cord / Q000098:blood supply / Q000473:pathology*