title: Changes in hematological parameters of athletes after receiving daily dose of a mixture of 12 amino acids for one month during the middle- and long-distance running training.
abstract: Previous studies have shown that a mixture of amino acids, consisting of 9 essential amino acids and 3 non-essential amino acids was effective in facilitating muscle recovery from athletic activities. In this study, the objective was to determine whether this amino acid mixture improved the physical condition and associated blood parameters of athletes in training when administered for a prolonged period. Thirteen college middle- and long-distance runners were placed in a 6-month experiment and received the amino acid mixture at the dose of 2.2 g/day for one month, 4.4 g/day for one month, and 6.6 g/day for one month with washout periods between test periods. The physical condition was scored and blood samples were collected before and after each test period. When the subjects received 2.2 g of the amino acid mixture three times a day, the physical condition was significantly improved along with increases in red blood cell count, hemoglobin, hematocrit, serum albumin, and fasting glucose, and a decrease in creatine phophokinase (p<0.05), suggesting increased hematopoiesis and glycogenesis, and rapid alleviation of muscle inflammation by the amino acid mixture.
authors: Department of Life Sciences (Sports Sciences), Graduate School of Arts and Sciences, The University of Tokyo, Japan. island817@aol.com
authors: M
authors: M
authors: Ohtani
authors: K
authors: K
authors: Maruyama
authors: S
authors: S
authors: Suzuki
authors: M
authors: M
authors: Sugita
authors: K
authors: K
authors: Kobayashi
mesh_terms: D000328:Adult; D000596:Amino Acids / Q000008:administration & dosage*; D001774:Blood Chemical Analysis; D001786:Blood Glucose / Q000378:metabolism; D003402:Creatine Kinase / Q000097:blood; D004906:Erythrocyte Count; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D018763:Muscle Fatigue / Q000187:drug effects*; D010809:Physical Fitness / Q000502:physiology*; D012420:Running / Q000502:physiology*; D013178:Sports Medicine
chemical_list: D000596:Amino Acids; D001786:Blood Glucose; D006454:Hemoglobins; D003402:Creatine Kinase