Amphiphilic, tri-block copolymers provide potent membrane-targeted neuroprotection.
Marks
J D
JD
Department of Pediatrics, University of Chicago, Chicago, Illinois 60637, USA. j-marks1@uchicago.edu
Pan
C Y
CY
Bushell
T
T
Cromie
W
W
Lee
R C
RC
D000818:Animals; D051033:Apoptosis Inducing Factor; D002118:Calcium / Q000378:metabolism; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D021961:Cell Membrane Structures / Q000187:drug effects; D019610:Cytoprotection; D004347:Drug Interactions; D018690:Excitatory Amino Acid Agonists / Q000494:pharmacology; D005420:Flavoproteins / Q000494:pharmacology; D015227:Lipid Peroxidation / Q000187:drug effects; D008565:Membrane Proteins / Q000494:pharmacology; D016202:N-Methylaspartate / Q000494:pharmacology; D009336:Necrosis; D009474:Neurons / Q000187:drug effects* / Q000473:pathology; D018696:Neuroprotective Agents / Q000494:pharmacology* / Q000627:therapeutic use; D020442:Poloxamer / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism / Q000502:physiology
C494831:Aifm1 protein, rat; D051033:Apoptosis Inducing Factor; D018690:Excitatory Amino Acid Agonists; D005420:Flavoproteins; D008565:Membrane Proteins; D018696:Neuroprotective Agents; D016194:Receptors, N-Methyl-D-Aspartate; D020442:Poloxamer; D016202:N-Methylaspartate; D002118:Calcium