Childhood melanoma in Europe since 1978: a population-based survival study.
The existence of the EUROCARE database now makes it possible to compare population-based survival for childhood melanoma in different European populations. The database contains verified information, including histological data, from cancer registries in 17 European countries, and as such it represents a particularly important source of survival information on a very rare cancer like childhood melanoma. The aim of the present paper was to describe survival in children with melanoma (MM), by sex, age and subsite, diagnosed during the period 1978--1989, using analysis of the data of the European pool of cases. Five year-survival for childhood MM diagnosed in 1978--1989 in Europe, is relatively good (80%; 95% confidence interval (CI) 47--95 for boys and 78%; 95% CI 58--91 for girls). Analysis by subsite, revealed the survival for MM on the head and neck, legs and arms was generally higher than survival for MM on other cutaneous sites (trunk, neck and scalp). For skin melanomas outcome for girls was better than boys, adjusting for age and sub-site. We suggest that the good survival observed in childhood MM seems to be related to early diagnosis.
Conti
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Servizio Integrato di Epidemiologia e Sistemi Informativi, Rome, Italy. sioepi@crs.ifo.it
Cercato
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MC
Gatta
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Ramazzotti
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Roscioni
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D000293:Adolescent; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D005060:Europe / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008545:Melanoma / Q000401:mortality*; D011379:Prognosis; D016016:Proportional Hazards Models; D017678:Sex Distribution; D012878:Skin Neoplasms / Q000401:mortality*; D016019:Survival Analysis; D015996:Survival Rate / Q000639:trends