Cerebellar metastasis from papillary serous adenocarcinoma of the ovary mimicking Ménière's disease. A case report.
BACKGROUND
In rare cases, cerebellar metastasis originating in serous papillary adenocarcinoma of the ovary can mimick Ménière's disease.


METHODS
A 51-year-old woman, with complete remission after optimal maximal debulking and chemotherapy for an International Federation of Gynecology and Obstetrics IIIc primary ovarian carcinoma, presented with nausea, vomiting, vertigo and headache 18 months after surgery. Investigations revealed a solitary cerebellar cystic mass, 4.6 x 4.0 x 3.2 cm. Gross total excision of the cerebellar lesion followed by brain irradiation resulted in complete resolution of her symptoms. Histology showed a metastatic tumor consistent with the primary ovarian carcinoma.


CONCLUSIONS
In an atypical presentation in patients with metastatic ovarian carcinoma, thorough investigations should be done to rule out or confirm brain metastasis, which can be aggressively managed to prevent serious consequences and improve outcome.
Chang
T C
TC
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Change Gung Memorial Hospital Linkou Medical Center and Chang Gung Medical College, Taoyuan, Taiwan. tinchang@ms4.hinet.net
Jain
S
S
Ng
K K
KK
Hsueh
S
S
Tsai
C S
CS
Chen
H L
HL
Chang
C N
CN
D000231:Adenocarcinoma, Papillary / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D002528:Cerebellar Neoplasms / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008575:Meniere Disease / Q000175:diagnosis*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology*; D012074:Remission Induction