Chronic myelomonocytic leukemia revealed by uncontrollable hematuria.
Nephrectomy was performed for uncontrollable unilateral hematuria in an apparently healthy 72-year-old man. The suburothelial connective tissue of the kidney was infiltrated by primitive myeloid cells with associated acute vasculitis and foci of extramedullary hematopoiesis. Subsequently, the patient was shown to have chronic myelomonocytic leukemia. Although renal involvement and vasculitis have been recorded previously in chronic myelomonocytic leukemia, this is the first occasion, to our knowledge, where their concurrence resulted in such a spectacular presentation.
Bane
A L
AL
Department of Histopathology, Central Pathology Laboratory, St. James's Hospital, Dublin 8, Ireland. anitabane@hotmail.com
Enright
H
H
Sweeney
E C
EC
D000368:Aged; D006417:Hematuria / Q000209:etiology*; D006801:Humans; D007668:Kidney / Q000473:pathology*; D015477:Leukemia, Myelomonocytic, Chronic / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D017254:Leukemic Infiltration / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D009392:Nephrectomy