title: Standardization of in vitro methods.
abstract: IgE-antibody analysis is a major diagnostic procedure and a primary tool in allergological research. The determination of sensitization frequencies and antibody concentrations against allergens of defined sources provides critical information for the estimation of the relative importance of food and environment in clinical allergy. True quantitation is essential and requires assay designs providing allergen excess and mass unit calibration. Standardized and reproducible methods show geographic and culture dependent differences between patient populations and contribute to the quality of diagnosis and treatment of allergic disease.
authors: Pharmacia Diagnostics AB, Uppsala, Sweden.
authors: L
authors: L
authors: Yman
mesh_terms: D000485:Allergens / Q000032:analysis* / Q000097:blood / Q000276:immunology; D000818:Animals; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis*; D007159:Immunologic Tests / Q000592:standards*; D017410:Practice Guidelines as Topic; D012015:Reference Standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D000485:Allergens