A method for the fabrication of low-noise carbon fiber nanoelectrodes.
A new and facile method has been developed for the fabrication of low-noise carbon fiber microelectrodes (CFMEs) and carbon fiber nanoelectrodes (CFNEs). The carbon fiber was flame-fuse sealed in the tip of the glass capillary. The CFMEs were made by cutting the protruding carbon fiber to the desired length, and the CFNEs were achieved by etching the protruding carbon on the flame to form a nanometer-scale tip. The tip of CFNEs can be controlled within the range from 100 to 300 nm. Thus, no epoxy wax was involved in the CFMEs and CFNEs. The experimental results of inspecting CFMEs and CFNEs by scanning electron microscopy demonstrated that the surface of the electrodes and the glass/fiber interface are very smooth. Therefore, the noise caused by the glass/fiber of these electrodes is much lower than that of the electrodes fabricated conventionlly. The electrodes were characterized by ferricyanide, catecholamine (dopamine,DA), norepinephrine (NE), and epinephrine (E)) and 5-hydroxytryptamine (5-HT) neurotransmitters using CV, LSV, DPV, and FSCV. The results showed that the CFMEs and CFNEs have very excellent electrochemical behavior and high sensitivity. The CV and DPV detection limits of DA, NE, and E are 7.6 x 10(-8), 7.0 x 10(-8), and 5.0 x 10(-8) mol/L, and the DPV detection limits of DA, NE, and E are 4.0 x 10(-8), 1.0 x 10(-7), and 2.2 x 10(-7) mol/L, respectively. This experiment offers a new and facile method for the fabrication of CFMEs and CFNEs of very high sensitivity and low noise.
Huang
W H
WH
Department of Chemistry, Wuhan University, China.
Pang
D W
DW
Tong
H
H
Wang
Z L
ZL
Cheng
J K
JK
D002244:Carbon; D002395:Catecholamines / Q000032:analysis; D005292:Ferricyanides / Q000032:analysis; D007202:Indicators and Reagents; D008839:Microelectrodes; D018377:Neurotransmitter Agents / Q000032:analysis
D002395:Catecholamines; D005292:Ferricyanides; D007202:Indicators and Reagents; D018377:Neurotransmitter Agents; C007931:hexacyanoferrate III; D002244:Carbon