Withanolide-type steroids from Solanum cilistum.
Six withanolide-type steroids, named as cilistols a, b, d, q, g and f, respectively, were isolated from the leaves of Solanum cilistum. The major component among them, cilistol a, was characterized as (22R, 24S, 25R, 26R)-1-oxo-22, 26; 24, 25-diepoxy-17alpha, 26-dihydroxyergost-2,5-diene on the basis of spectroscopic properties and X-ray crystallographic analysis; the other isolated compounds had closely related structures. This is the first report of withanolide-type steroids in the Solanum genera.
Zhu
X H
XH
Faculty of Pharmaceutical Sciences, Kumamoto University, Japan.
Takagi
M
M
Ikeda
T
T
Midzuki
K
K
Nohara
T
T
D004875:Ergosterol / Q000031:analogs & derivatives*; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D010840:Phytosterols / Q000737:chemistry* / Q000302:isolation & purification; D019657:Solanaceae / Q000737:chemistry*
D010840:Phytosterols; D004875:Ergosterol