Enzymatic vitreous surgery.
Enzymatic manipulation of the vitreous and vitreoretinal juncture is currently in the process of being evaluated in many centers around the world. The goals of such manipulation are either to disinsert the posterior hyaloid from the retina surface in an atraumatic, very clean, cleavage plane or, at this point, to try to disinsert the peripheral vitreous from the neurosensory retina. In addition, enzymatic manipulation of the central vitreous in terms of liquefaction has also been evaluated. Although this is certainly the beginning of this type of vitreal surgery, adjuvant or alternative, it does appear to be a new and exciting area of vitreoretinal surgery.
Trese
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Associated Retinal Consultants, PC, William Beaumont Hospital, Royal Oak, MI 48073, USA.
D000818:Animals; D002810:Chondroitinases and Chondroitin Lyases / Q000008:administration & dosage; D004798:Enzymes / Q000008:administration & dosage*; D005128:Eye Diseases / Q000601:surgery; D005341:Fibrinolysin / Q000008:administration & dosage; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006801:Humans; D007267:Injections; D007432:Intraoperative Period; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage; D014821:Vitrectomy / Q000379:methods*; D014822:Vitreous Body / Q000187:drug effects / Q000601:surgery*
D004798:Enzymes; D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator; D005341:Fibrinolysin; D002810:Chondroitinases and Chondroitin Lyases