Colonization with Schizophyllum commune of localized honeycomb lung with mucus.
We report a surgical case involving localized honeycomb lung with mucus, caused by colonization of a Schizophyllum commune, which displayed a tumorous shadow in the right upper mediastinum. A 74-year-old male with a history of tuberculosis in the 1970s was referred to Chiba University Hospital (Chiba, Japan) with an abnormal shadow evident in the chest roentgenogram. A transbronchial biopsy failed to yield a definite diagnosis. We resected the right upper lobe, which was found to contain a consolidative lesion filled with viscous mucus in the right upper lobe adjacent to the right upper mediastinum. Microscopic examination revealed a honeycomb lung formation with mucus in the destroyed space. Culture of the mucus yielded a whitish filamentous fungus, positively identified as S. commune. This is the first report of S. commune leading to a deposit of mucus and the formation of a consolidative lesion in the destroyed lung.
Iizasa
T
T
Department of Surgery, Institute of Pulmonary Cancer Research, Chiba University, Chiba, Japan.
Kamei
K
K
Chiyo
M
M
Suzuki
M
M
Baba
M
M
Toyosaki
T
T
Hiroshima
K
K
Ohwada
H
H
Kanno
S
S
Nishimura
K
K
Fujisawa
T
T
D000368:Aged; D006801:Humans; D008168:Lung / Q000382:microbiology / Q000473:pathology; D008172:Lung Diseases, Fungal / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D008297:Male; D009093:Mucus; D012567:Schizophyllum / Q000302:isolation & purification