Novel single nucleotide polymorphisms of the human colony-stimulating factor 2 (CSF2) gene identified by sequencing the entire gene.
We describe three single nucleotide polymorphisms (SNPs) of the human colony-stimulating factor 2 (CSF2) gene and their allelic frequencies, as determined by direct sequencing of 48 alleles of the entire CSF2 gene. Three polymorphisms were identified, at nucleotide positions 1816 (T/C), 2284 (C/T), and 3079 (G/A). These polymorphisms will be useful in genetic studies not only of hematologic disorders but also of disorders of bone metabolism.
Kajita
M
M
Department of Molecular Biology, Institute of Gerontology, Nippon Medical School, Kawasaki, Japan.
Iwasaki
H
H
Ota
N
N
Shinohara
Y
Y
Kodaira
M
M
Nakajima
T
T
Emi
M
M
D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000235:genetics*; D006801:Humans; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide; D017422:Sequence Analysis, DNA
D016178:Granulocyte-Macrophage Colony-Stimulating Factor