title: Thuricin 7: a novel bacteriocin produced by Bacillus thuringiensis BMG1.7, a new strain isolated from soil.
abstract: OBJECTIVE
  Detection and identification of new antagonistic activities towards Bacillus cereus and relatives.
  
  
  RESULTS
  Twenty Bacillus thuringiensis strains were screened for their capacity to express bacteriocin-like agents. Strain BMG1.7, isolated from soil, showed an antagonistic activity called thuricin 7. Thuricin 7 was active against several species of the genus Bacillus, including three of the four known B. thuringiensis/B. cereus bacteriocin producers, as well as against Streptococcus pyogenes and Listeria monocytogenes strains. Antimicrobial activity was lost after treatment with proteinase K. The active protein had an apparent molecular weight of 11.6 kDa, and was secreted at the end of the exponential growth phase. Thuricin 7 retained 55% of the activity after incubation at 98 degrees C for 30 min. The mode of action of thuricin 7 was shown to be bactericidal and bacteriolytic.
  
  
  CONCLUSIONS
  Thuricin 7 is a novel bacteriocin produced by a newly isolated Bacillus thuringiensis strain BMG1.7.
  
  
  CONCLUSIONS
  The characteristics of thuricin 7 indicate that it is a new bacteriocin which may have interesting biotechnological applications due to its relatively large activity spectrum.
authors: Laboratoire de Microbiologie, Département de Biologie, Faculté des Sciences de Tunis, Tunisia. ameur.cherif@fst.rnu.tn
authors: A
authors: A
authors: Cherif
authors: H
authors: H
authors: Ouzari
authors: D
authors: D
authors: Daffonchio
authors: H
authors: H
authors: Cherif
authors: K
authors: K
authors: Ben Slama
authors: A
authors: A
authors: Hassen
authors: S
authors: S
authors: Jaoua
authors: A
authors: A
authors: Boudabous
mesh_terms: D001409:Bacillus cereus / Q000187:drug effects; D001413:Bacillus thuringiensis / Q000187:drug effects / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism*; D001430:Bacteriocins / Q000096:biosynthesis* / Q000302:isolation & purification* / Q000494:pharmacology; D003470:Culture Media; D006094:Gram-Positive Bacteria / Q000187:drug effects; D012988:Soil Microbiology
chemical_list: D001430:Bacteriocins; D003470:Culture Media; C059740:thuricin