A three-dimensional model for ciliary motion based on the internal 9+2 structure.
Here we present, to our knowledge, the first modelling platform that enables simulations of three-dimensional (3D) motion of multicilia arrays at a detailed level. It consists of three building blocks: (i) geometric equations for tracking the 3D motion of the cilia, (ii) a hydrodynamic description of the ciliary system, and (iii) model equations for the internal bend generating based on the 9 + 2 structure. The model generates seemingly realistic 3D beat patterns and demonstrates metachronal coordination that evolves autonomously as a result of the hydrodynamic coupling between the cilia. We study the effect of the twisting motion within the cilia and propose a conjecture on a possible role of the radial spokes system.
Gueron
S
S
Department of Mathematics, University of Haifa, Israel. shay@math.haifa.ac.il
Levit-Gurevich
K
K
D002923:Cilia / Q000502:physiology* / Q000648:ultrastructure; D004398:Dyneins / Q000737:chemistry* / Q000502:physiology*; D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological; D008961:Models, Structural; D009068:Movement
D004398:Dyneins