Effect of bovine small intestine thioredoxin on aldose reductase activity.
Under oxidative stress mediated by H(2)O(2), significant activation of purified aldose reductase from bovine small intestine was observed in the presence of purified thioredoxin from bovine small intestine.
Mizoguchi
T
T
Otemae Junior College, 2-2-2 Inano, Itami, 664-0861, Hyogo, Japan. mizoguti@otemae.ac.jp
Maeda
I
I
Yagi
K
K
Kador
P F
PF
D000449:Aldehyde Reductase / Q000378:metabolism*; D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D002417:Cattle; D004220:Disulfides / Q000378:metabolism; D004789:Enzyme Activation / Q000187:drug effects; D006861:Hydrogen Peroxide / Q000633:toxicity; D066298:In Vitro Techniques; D007421:Intestine, Small / Q000187:drug effects / Q000378:metabolism*; D018384:Oxidative Stress; D013880:Thioredoxin-Disulfide Reductase / Q000378:metabolism; D013879:Thioredoxins / Q000302:isolation & purification / Q000378:metabolism* / Q000494:pharmacology
D000975:Antioxidants; D004220:Disulfides; D013879:Thioredoxins; D006861:Hydrogen Peroxide; D000449:Aldehyde Reductase; D013880:Thioredoxin-Disulfide Reductase