Classical malignant rhabdoid tumor of central nervous system in 9-year-old Korean.
A Malignant rhabdoid tumor (MRT) arising in the right temporoparietal lobe of a 9-year-old boy is described along with the results of an immunohistochemical study. The patient initially sought medical attention for a ptosis and right sided headache. The child underwent a subtotal resection of the tumor, followed by radiotherapy and systemic chemotherapy, but died three years after surgery. A MRT, a primary neoplasm of the central nervous system (CNS), is an entity of unknown histogenesis with a dismal prognosis, which only occurs in early childhood. Histologically similar tumors with more varied morphological features have been designated as an atypical teratoid/rhabdoid tumor. However, a classical MRT is extremely rare in the CNS and our case represents a classical CNS MRT.
Chang
H K
HK
Department of Pathology, Medical College of Kosin University, Pusan, Korea. changhkg@ns.kosinmed.or.kr
Kim
J H
JH
D001932:Brain Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000628:therapy; D002648:Child; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D018335:Rhabdoid Tumor / Q000378:metabolism* / Q000473:pathology / Q000628:therapy; D014746:Vimentin / Q000032:analysis
D005904:Glial Fibrillary Acidic Protein; D014746:Vimentin