title: [Periodontitis: a hidden chronic infection].
abstract: Periodontitis is a chronic inflammatory disease of the tooth supporting tissues which has a prevalence of 35% in the adult population. Risk factors are dental plaque, calculus, smoking, diabetes mellitus, stress and genetic traits. In parallel with chronic intestinal inflammatory diseases and stomach cancer, gene polymorphisms in the interleukin-I gene family are associated with severity of periodontitis. Periodontitis is usually painless. Symptoms of the disease are bleeding, redness and swelling of the gums, suppuration and migration of teeth. Halitosis may be present. Treatment of periodontitis involves supra- and subgingival mechanical debridement, oral hygiene instruction and surgical elimination of residual deepened and bleeding pockets on indication. Microbiological testing can be used to select patients who may benefit from additional systemic antimicrobial therapy. Periodontal lesions may act as a portal of entry for dissemination of periodontal bacteria into the blood stream, which may result in extraoral infections. For this reason it is recommended to include diagnosis of periodontitis in focal examination. Associations have been documented between periodontitis and cardiovascular diseases, arthritis and premature low birth weight infants.
authors: Academisch Centrum Tandheelkunde Amsterdam, afd. Orale Biologie, sectie Klinische Parodontale Microbiologie, Van der Boechorststraat 7, 1081 BR Amsterdam. diagnost@nedernet.nl
authors: A J
authors: AJ
authors: van Winkelhoff
authors: E G
authors: EG
authors: Winkel
authors: C M
authors: CM
authors: Vandenbroucke-Grauls
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D005891:Gingivitis / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008297:Male; D010514:Periodontal Pocket / Q000175:diagnosis / Q000628:therapy; D010518:Periodontitis / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy*; D011247:Pregnancy; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents