Successful treatment of vancomycin-resistant Enterococcus endocarditis with oral linezolid.
We report a case of vancomycin-resistant Enterococcus faecium endocarditis that failed to respond to sequential monotherapy with chloramphenicol and quinupristin/dalfopristin but was successfully treated with oral linezolid.
Babcock
H M
HM
Infectious Disease Division, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. hbabcock@im.wustl.edu
Ritchie
D J
DJ
Christiansen
E
E
Starlin
R
R
Little
R
R
Stanley
S
S
D000081:Acetamides / Q000008:administration & dosage / Q000627:therapeutic use*; D000284:Administration, Oral; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004697:Endocarditis, Bacterial / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D016984:Enterococcus faecium / Q000187:drug effects*; D005260:Female; D005500:Follow-Up Studies; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D006801:Humans; D000069349:Linezolid; D023303:Oxazolidinones / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome; D020713:Vancomycin Resistance
D000081:Acetamides; D000900:Anti-Bacterial Agents; D023303:Oxazolidinones; D000069349:Linezolid