title: A common class of nematode glutathione S-transferase (GST) revealed by the theoretical proteome of the model organism Caenorhabditis elegans.
abstract: The genome verified C. elegans free-living nematode model is a new tool for investigating gene expression in human and animal nematode parasites. There is limited information on designating glutathione S-transferase (GST) to specific classes in lower invertebrates such as nematodes. Following cloning, amino acid sequence alignment, recombinant expression and Western blotting we provide evidence of a new GST class in nematodes or lower invertebrates.
authors: Institute of Biological Sciences, Edward Llwyd Building, University of Wales, Ceredigion, Wales, SY23 3DA, Aberystwyth, UK. amc99@aber.ac.uk
authors: A M
authors: AM
authors: Campbell
authors: P H
authors: PH
authors: Teesdale-Spittle
authors: J
authors: J
authors: Barrett
authors: E
authors: E
authors: Liebau
authors: J R
authors: JR
authors: Jefferies
authors: P M
authors: PM
authors: Brophy
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017173:Caenorhabditis elegans / Q000201:enzymology*; D029742:Caenorhabditis elegans Proteins / Q000737:chemistry; D003001:Cloning, Molecular; D005982:Glutathione Transferase / Q000737:chemistry / Q000145:classification*; D007700:Kinetics; D051379:Mice; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009348:Nematoda / Q000201:enzymology*; D010271:Parasites / Q000201:enzymology; D010802:Phylogeny; D020543:Proteome / Q000737:chemistry; D016415:Sequence Alignment; D013379:Substrate Specificity
chemical_list: D029742:Caenorhabditis elegans Proteins; D020543:Proteome; D005982:Glutathione Transferase