title: Gross motor function of children with down syndrome: creation of motor growth curves.
abstract: OBJECTIVE
  To create gross motor function growth curves for children with Down syndrome (DS) and to estimate the probability that motor functions are achieved by different ages.
  
  
  METHODS
  Nonlinear growth curve analysis by using a 2-parameter (rate, upper limit) model.
  
  
  METHODS
  Early intervention programs, schools, and children's homes.
  
  
  METHODS
  One hundred twenty-one children with DS, ages 1 month to 6 years.
  
  
  METHODS
  Gross Motor Function Measure (GMFM) and severity of motor impairment.
  
  
  RESULTS
  The curves for children with mild (n = 51) and moderate/severe (n = 70) impairment were characterized by a greater increase in GMFM scores during infancy and smaller increases as the children approached the predicted maximum score of 85.9 or 87.9. The estimated probability that a child would roll by 6 months was 51%; sit by 12 months, 78%; crawl by 18 months, 34%; walk by 24 months, 40%; and run, walk up stairs, and jump by 5 years, 45% to 52%.
  
  
  CONCLUSIONS
  Children with DS require more time to learn movements as movement complexity increases. Impairment severity affected the rate but not the upper limit of motor function. The results have implications for counseling parents, making decisions about motor interventions, and anticipating the time frame for achievement of motor functions.
authors: Department of Rehabilitation Sciences, MCP Hahnemann University, Philadelphia, PA 19102-1192, USA. robert.j.palisano@drexel.edu
authors: R J
authors: RJ
authors: Palisano
authors: S D
authors: SD
authors: Walter
authors: D J
authors: DJ
authors: Russell
authors: P L
authors: PL
authors: Rosenbaum
authors: M
authors: M
authors: Gémus
authors: B E
authors: BE
authors: Galuppi
authors: L
authors: L
authors: Cunningham
mesh_terms: D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009048:Motor Skills / Q000145:classification*; D011336:Probability; D011446:Prospective Studies; D012016:Reference Values; D012044:Regression Analysis