title: Endovascular venous stenting in May-Thurner syndrome.
abstract: BACKGROUND
  Chronic pulsatile compression of the left common iliac vein between the crossing right common iliac artery and the lowest lumbar vertebral body may induce focal intimal proliferation of the vein (May-Thurner syndrome), resulting in impaired venous return and left iliofemoral thrombosis. Corrective surgical treatment requires extensive dissection. In this report, we describe our experience with endovascular venous stenting in May-Thurner syndrome.
  
  
  METHODS
  Six patients with symptomatic May-Thurner syndrome were treated with percutaneous transluminal angioplasty and implantation of self-expanding stents. RESULTS Postprocedure phlebography revealed patent iliofemoral veins with unimpeded venous outflow and disappearance of collaterals in all patients. No procedure-related complications occurred. At follow-up (median, 12 months), 5 of 6 patients were free of symptoms. In one patient lower extremity edema was aggravated despite a patent stented segment of the left iliac vein. The patient continues to wear support stockings to compensate for continuing venous insufficiency. Color coded duplex scanning revealed patency at regular intervals in 5 patients. In one patient, occlusion of the stented venous segment with return of symptoms was detected at one month. Patency could not be restored despite catheter-directed thrombolytic therapy. After angioplasty, however, adequate collateral circulation was restored and symptoms resolved completely.
  
  
  CONCLUSIONS
  Endovascular venous stenting in May-Thurner syndrome is technically feasible, and leads to reduction of symptoms in the majority of patients with high patency rates in the medium-term. This approach may prove to be a percutaneous alternative to surgical treatment.
authors: Departments of Vascular Surgery, St. Antonius Hospital, Nieuwegein, The Netherlands.
authors: R H
authors: RH
authors: Heijmen
authors: T L
authors: TL
authors: Bollen
authors: D A
authors: DA
authors: Duyndam
authors: T T
authors: TT
authors: Overtoom
authors: J C
authors: JC
authors: Van Den Berg
authors: F L
authors: FL
authors: Moll
mesh_terms: D000328:Adult; D000800:Angioplasty, Balloon; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D007084:Iliac Vein / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011859:Radiography; D015607:Stents; D013577:Syndrome; D017539:Tunica Intima / Q000473:pathology; D014689:Venous Insufficiency / Q000209:etiology; D020246:Venous Thrombosis / Q000209:etiology