[Benign unclassified tumor of the gonadal stroma: importance of alpha-inhibin expression].
We present a begin unclassified gonadal stroma tumor in a 62 year-old menopausal woman. We discuss the differential diagnosis with the most frequent fibromas and thecomas and with the rarer sclerosing stromal tumor of the ovary. The immunohistochemical staining for alpha-inhibin was important to confirm the origin of the spindle-cell proliferation from undifferentiated (unclassified) ovarian gonadal stroma.
Sironi
M
M
Unità Operativa di Anatomia Patologica, Ospedale S. Corona, Azienda Ospedaliera G. Salvini, Viale Forlanini 121, I-20024 Garbagnate Milanese, MI. anapatg@aogarbagnate.lombardia.it
Santangelo
M
M
Pasquinelli
G
G
Spinelli
M
M
D000199:Actins / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D003893:Desmin / Q000032:analysis; D005260:Female; D005350:Fibroma / Q000175:diagnosis; D006801:Humans; D016130:Immunophenotyping; D007265:Inhibins / Q000032:analysis*; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000032:analysis*; D010051:Ovarian Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D011980:Receptors, Progesterone / Q000032:analysis; D009418:S100 Proteins / Q000032:analysis; D018312:Sex Cord-Gonadal Stromal Tumors / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D013798:Thecoma / Q000175:diagnosis; D014746:Vimentin / Q000032:analysis
D000199:Actins; D014408:Biomarkers, Tumor; D003893:Desmin; D009363:Neoplasm Proteins; D011980:Receptors, Progesterone; D009418:S100 Proteins; D014746:Vimentin; C094377:inhibin-alpha subunit; D007265:Inhibins