Pedal interdigital condylomata lata: a rare sign of secondary syphilis.
BACKGROUND
Condylomata lata of the toe webs are uncommon manifestations of secondary syphilis. Considering the recent decline in the incidence of syphilis in the United States, such lesions are likely to present infrequently. In some cases, this phenomenon may be the only physical sign of syphilis; therefore, it is important that a high index of suspicion is maintained when evaluating toe web lesions in patients at epidemiologic risk for syphilis.


OBJECTIVE
A case of secondary syphilis presenting solely with interdigital condyloma lata in the toe web spaces is reported, and similar cases reported in the literature are reviewed.


METHODS
This article documents the diagnosis of secondary syphilis based on a positive serology in conjunction with the development of interdigital condyloma lata as the only physical finding suggestive of lues.


RESULTS
The latter lesions resolved after appropriate, adequate antibiotic therapy.


CONCLUSIONS
A case of condylomata lata of the toe webs without other pertinent physical findings is presented. Analogous to lesions typically seen in the anogenital region, moist exophytic toe web plaques may represent condyloma lata and thereby be a sign of secondary syphilis. The differential diagnosis includes tinea pedis, erythrasma, macerated corns, verrucae, and several tropical mycoses (chromomycosis, mycetoma).
Rosen
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Department of Dermatology, Baylor College of Medicine, Houston, Texas 77030, USA. VampireTed@aol.com
Hwong
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D000328:Adult; D003937:Diagnosis, Differential; D005534:Foot Diseases / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D013591:Syphilis, Cutaneous / Q000097:blood / Q000175:diagnosis* / Q000473:pathology