Lower faecal egg excretion in chemically-induced diabetic mice infected with Schistosoma mansoni due to impaired egg maturation.
The effect of streptozotocin-induced diabetes mellitus was studied in mice infected with Schistosoma mansoni. Faecal egg excretion was lower in diabetic mice but worm load and total amount of eggs in the intestine tissue were equal to the control group. Evaluation of an oogram showed a great number of immature dead eggs and a low number of mature eggs in diabetic mice. It was therefore concluded that faecal egg excretion was lower in diabetic mice due to impaired egg maturation.
Hulstijn
M
M
Curso de Biologia Parasitária, Instistuto Oswaldo Cruz, Fiocruz, Rio de Janeiro, RJ, 21045-900, Brasil. hulstijn@ioc.fiocruz.br
Oliveira
R M
RM
Moura
E G
EG
Machado-Silva
J R
JR
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000469:parasitology*; D005243:Feces / Q000469:parasitology; D051379:Mice; D010063:Ovum / Q000254:growth & development; D010270:Parasite Egg Count; D012555:Schistosomiasis mansoni; D013311:Streptozocin; D013997:Time Factors
D013311:Streptozocin