title: Caspases: more than just killers?
abstract: Proteases of the caspase family constitute the central executioners of apoptosis. Several recent observations suggest that caspases and apoptosis-regulatory molecules exert important functions beyond that of cell death, including the control of T-cell proliferation and cell-cycle progression. Here, Los and colleagues propose a model that directly connects cell suicide mechanisms to the regulation of cell-cycle progression.
authors: Dept of Immunology and Cell Biology, University of Münster, D-48149, Münster, Germany. los@uni-muenster.de
authors: M
authors: M
authors: Los
authors: C
authors: C
authors: Stroh
authors: R U
authors: RU
authors: Jänicke
authors: I H
authors: IH
authors: Engels
authors: K
authors: K
authors: Schulze-Osthoff
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000276:immunology*; D020169:Caspases / Q000502:physiology / Q000633:toxicity*; D006801:Humans; D013601:T-Lymphocytes / Q000166:cytology / Q000201:enzymology
chemical_list: D020169:Caspases