title: The relationship between physicians' self-reported target fasting blood glucose levels and metabolic control in type 2 diabetes. The QuED Study Group--quality of care and outcomes in type 2 diabetes.
abstract: OBJECTIVE
  To investigate the relationship between beliefs of physicians relative to intensive metabolic control in type 2 diabetes and levels of HbA1c obtained in a sample of their patients.
  
  
  METHODS
  Physicians' beliefs were investigated through a questionnaire sent to a sample of self-selected clinicians participating in a nationwide initiative aimed at assessing the relationship between the quality of care delivered to patients with type 2 diabetes and their outcomes. At the same time, physicians were asked to collect clinical data on a random sample of their patients, stratified by age (<65 vs. > or = 65 years). Mean HbA1c levels in the study population were thus evaluated according to target fasting blood glucose (FBG) used by their physicians.
  
  
  RESULTS
  Of 456 physicians, 342 (75%) returned the questionnaire. Among the responders, 200 diabetologists and 99 general practitioners (GPs) recruited 3,297 patients; 2,003 of whom were always followed by the same physician and 1,294 of whom were seen by different physicians in the same structure on different occasions. Only 14% of the respondents used target FBG levels < or = 6.1 mmol/l, whereas 38% pursued values >7.8 mmol/l, with no statistically significant difference between diabetologists and GPs. The analysis of the relationship between FBG targets and metabolic control, restricted to those patients always seen by the same physician, showed a strong linear association, with mean HbA1c values of 7.0 +/- 1.6 for patients in the charge of physicians pursuing FBG levels < or = 6.1 mmol/l and 7.8 +/- 1.8 for those followed by physicians who used target values >7.8 mmol/l. After adjusting for patients' and physicians' characteristics, the risk of having HbA1c values > 7.0% was highly correlated with physicians' beliefs. Patients followed by different physicians in the same unit showed a risk of inadequate metabolic control similar to that of patients followed by physicians adopting a nonaggressive policy.
  
  
  CONCLUSIONS
  Doctors adopt extremely heterogeneous target FBG levels in patients with type 2 diabetes, which in turn represent an important independent predictor of metabolic control. To improve patient outcomes, physicians-centered educational activities aimed at increasing the awareness of the potential benefits of a tight metabolic control in patients with type 2 diabetes are urgently needed.
authors: Department of Clinical Pharmacology and Epidemiology, Istituto di Ricerche Farmacologiche Mario Negri, Consorzio Mario Negri Sud, S. Maria Imbaro, Italy.
authors: M
authors: M
authors: Belfiglio
authors: G
authors: G
authors: De Berardis
authors: M
authors: M
authors: Franciosi
authors: D
authors: D
authors: Cavaliere
authors: B
authors: B
authors: Di Nardo
authors: S
authors: S
authors: Greenfield
authors: S H
authors: SH
authors: Kaplan
authors: F
authors: F
authors: Pellegrini
authors: M
authors: M
authors: Sacco
authors: G
authors: G
authors: Tognoni
authors: M
authors: M
authors: Valentini
authors: A
authors: A
authors: Nicolucci
authors: V
authors: V
authors: Caimi
authors: F
authors: F
authors: Capani
authors: A
authors: A
authors: Corsi
authors: R
authors: R
authors: Della Vedova
authors: M
authors: M
authors: Massi Benedetti
authors: A
authors: A
authors: Nicolucci
authors: C
authors: C
authors: Taboga
authors: M
authors: M
authors: Tombesi
authors: G
authors: G
authors: Vespasiani
mesh_terms: D000368:Aged; D001786:Blood Glucose / Q000032:analysis*; D015992:Body Mass Index; D003695:Delivery of Health Care / Q000592:standards*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000378:metabolism / Q000628:therapy*; D005215:Fasting; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D010820:Physicians; D011785:Quality Assurance, Health Care; D011795:Surveys and Questionnaires
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin