Applications of microarray technology in breast cancer research.
Microarrays provide a versatile platform for utilizing information from the Human Genome Project to benefit human health. This article reviews the ways in which microarray technology may be used in breast cancer research. Its diverse applications include monitoring chromosome gains and losses, tumour classification, drug discovery and development, DNA resequencing, mutation detection and investigating the mechanism of tumour development.
Cooper
C S
CS
The Institute of Cancer Research, Sutton, Surrey, UK. csc@icr.ac.uk
D001943:Breast Neoplasms / Q000235:genetics* / Q000378:metabolism; D002874:Chromosome Mapping; D004273:DNA, Neoplasm / Q000032:analysis*; D015870:Gene Expression; D020869:Gene Expression Profiling; D015894:Genome, Human; D006801:Humans; D009693:Nucleic Acid Hybridization; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D014158:Transcription, Genetic
D004273:DNA, Neoplasm