Infantile hypertrophic pyloric stenosis and asymptomatic joint hypermobility.
A significant association with asymptomatic joint hypermobility was observed in 37 children with a history of infantile hypertrophic pyloric stenosis (P =.0016) and their parents (mothers, P <.0001; fathers, P <.05). The subjects with articular hypermobility showed an increased frequency of absent mandibular frenulum, thereby suggesting the presence of a previously unrecognized, systemic abnormality of the extracellular matrix.
De Felice
C
C
Department of Preventive Pediatrics and Neonatology, Institute of General Surgery and Surgical Specialties, University of Siena, Siena, Italy.
Di Maggio
G
G
Toti
P
P
Parrini
S
S
Salzano
A
A
Lagrasta
U E
UE
Bagnoli
F
F
D005109:Extracellular Matrix / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D007593:Joint Instability / Q000150:complications* / Q000175:diagnosis; D008297:Male; D011707:Pyloric Stenosis / Q000150:complications* / Q000473:pathology / Q000601:surgery