title: Shared antigenicity between Helicobacter pylori and periodontopathic Campylobacter rectus strains.
abstract: Periodontopathic Campylobacter rectus strains possess 41- and 68-kDa proteinaceous antigens which share antigenicity with antigens of Helicobacter pylori strains. H. pylori strains have a 54-kDa antigen which reacts with C. rectus strains. We found that the salivary IgA levels against H. pylori were correlated with those against C. rectus. These cross-reactive antigens of C. rectus may affect the serological diagnosis of H. pylori infections, especially when saliva is used. It is possible that these cross-reacting antigens may relate to the induction of immunopathological responses against both microorganisms.
authors: Department of Microbiology, Oral Science Center, Tokyo Dental College, Chiba, Japan. ishihara@tdc.ac.jp
authors: K
authors: K
authors: Ishihara
authors: T
authors: T
authors: Miura
authors: Y
authors: Y
authors: Ebihara
authors: T
authors: T
authors: Hirayama
authors: S
authors: S
authors: Kamiya
authors: K
authors: K
authors: Okuda
mesh_terms: D000942:Antigens, Bacterial / Q000276:immunology*; D002167:Campylobacter / Q000276:immunology*; D002169:Campylobacter Infections / Q000382:microbiology; D003429:Cross Reactions; D016481:Helicobacter Infections / Q000382:microbiology; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D015151:Immunoblotting; D007071:Immunoglobulin A, Secretory / Q000032:analysis / Q000276:immunology*; D010437:Peptic Ulcer / Q000382:microbiology; D010510:Periodontal Diseases / Q000382:microbiology; D012463:Saliva / Q000276:immunology
chemical_list: D000942:Antigens, Bacterial; D007071:Immunoglobulin A, Secretory