Improving patient recruitment to multicentre clinical trials: the case for employing a data manager in a district general hospital-based oncology centre.
One of the most frequently cited reasons for poor recruitment to multicentre randomized clinical trials is the additional workload placed on clinical staff. We report the effect on patient recruitment of employing a data manager to support clinical staff in an English district general hospital (DGH). In addition, we explore the effect data managers have on the quality of data collected, proxied by the number of queries arising with the trial organizers. We estimate that the cost of employing a data manager on a full-time basis is 502 per patient recruited but may amount to 326 if the appointment is part-time. Data quality is high when full responsibility lies with a data manager but falls when responsibility is shared. Whether the costs of employing a data manager to recruit patients from a DGH are worth incurring depends on the value placed on the speed at which multicentre trials can be completed, how important it is to broaden the research base beyond the traditional setting of teaching hospitals, and the amount of evaluative data required.
Street
A
A
Centre for Health Economics, University of York, UK. ads6@york.ac.uk
Strong
J
J
Karp
S
S
D002986:Clinical Trials as Topic; D003365:Costs and Cost Analysis; D004739:England; D006801:Humans; D019451:Information Management; D015337:Multicenter Studies as Topic; D018579:Patient Selection; D012109:Research Support as Topic; D012456:Salaries and Fringe Benefits; D000078329:Workforce; D016526:Workload