Brain natriuretic peptide and cardiac rupture after acute myocardial infarction.
Cardiac rupture is a fatal complication in the acute stage of myocardial infarction (MI). However, no measures have yet been established to predict it. Herein we describe three MI patients with cardiac rupture in whom plasma brain natriuretic peptide (BNP) and atrial natriuretic peptide (ANP) concentrations had been serially monitored from the onset of MI to cardiac rupture. In these cases, plasma BNP levels increased without symptomatic and hemodynamic changes and reached their highest level immediately before cardiac rupture, while plasma ANP levels remained unchanged. These cases suggest that the increased plasma BNP concentrations without symptomatic and hemodynamic changes may be a useful marker for predicting cardiac rupture after acute MI.
Arakawa
N
N
Second Department of Internal Medicine, Iwate Medical University, Morioka.
Nakamura
M
M
Endo
H
H
Sugawara
S
S
Suzuki
T
T
Hiramori
K
K
D000368:Aged; D009320:Atrial Natriuretic Factor / Q000097:blood*; D005260:Female; D006342:Heart Rupture, Post-Infarction / Q000097:blood* / Q000175:diagnosis; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000097:blood*; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D011379:Prognosis
D020097:Natriuretic Peptide, Brain; D009320:Atrial Natriuretic Factor