[Neostigmine treatment of acute pseudo-obstruction of colon (Ogilvie syndrome)].
In a 77-year-old male patient with Parkinson's disease and with acute pseudo-obstruction of the colon (Ogilvie's syndrome) conservative therapy was ineffective. Neostigmine was recently shown to be effective and safe for the treatment of Ogilvie's syndrome. Intravenous neostigmine treatment caused a prompt clinical and radiological response in the patient. Early recognition of the condition and prompt neostigmine treatment if conservative measures fail is important to reduce the risk of bowel perforation.
Koornstra
J J
JJ
Afd. Interne Geneeskunde, Academisch Ziekenhuis, Postbus 30.001, 9700 RB Groningen.
Klaver
N S
NS
ter Maaten
J C
JC
Limburg
A J
AJ
van der Jagt
E J
EJ
van der Werf
T S
TS
D000368:Aged; D003112:Colonic Pseudo-Obstruction / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007262:Infusions, Intravenous; D007416:Intestinal Perforation / Q000517:prevention & control; D008297:Male; D009388:Neostigmine / Q000008:administration & dosage / Q000627:therapeutic use*; D010277:Parasympathomimetics / Q000008:administration & dosage / Q000627:therapeutic use*; D010300:Parkinson Disease / Q000150:complications*; D016896:Treatment Outcome
D010277:Parasympathomimetics; D009388:Neostigmine