title: The Visi-Chroma VC-100: a new imaging colorimeter for dermatocosmetic research.
abstract: OBJECTIVE
  It was the aim of this study to carry out a comparative evaluation in vitro on standardized color charts and in vivo on healthy subjects using the Visi-Chroma VC-100, a new imaging tristimulus colorimeter and the Minolta Chromameter CR-200 as a reference instrument. The Visi-Chroma combines tristimulus color analysis with full color visualization of the skin area measured. The technical performances of both instruments were compared with the purpose of validating the use of this new imaging colorimeter in dermatocosmetic research.
  
  
  METHODS
  In vitro L*a*b* color parameters were taken with both instruments on standardized color charts (Macbeth and RAL charts) in order to evaluate accuracy, sensitivity range and repeatability. These measurements were completed by in vivo studies on different sites of human skin and studies of color changes induced by topical chemical agents on forearm skin. The accuracy, sensitivity range and repeatability of measurements of selected distances and surfaces in the measuring zone considered and specific color determinations of specific skin zones were also determined.
  
  
  RESULTS
  The technical performance of this imaging colorimeter was rather good, with low coefficients of variation for repeatability of in vitro and vivo color measurements. High positive correlations were established in vitro and in vivo over a wide range of color measurements. The imaging colorimeter was able to measure the L*a*b* color parameters of specific chosen parts of the skin area considered and to measure accurately selected distances and surfaces in the same skin site considered.
  
  
  CONCLUSIONS
  These comparative measurements show that both instruments have very similar technical performances and that high levels of correlation were obtained in vitro and in vivo using the L*a*b* color parameters. In addition, the Visi-Chroma presents the following improvements: 1) direct visualization and recording of the skin area considered with concomitant color measurements; 2) determination of the specific color parameters of skin areas chosen in the total measuring area; and 3) accurate determination of selected distances and surfaces in the same skin areas chosen.
authors: Faculty of Physical Education and Physiotherapy, Free University of Brussels (VUB), Brussels, USA. anbarel@vub.ac.be
authors: A O
authors: AO
authors: Barel
authors: P
authors: P
authors: Clarys
authors: K
authors: K
authors: Alewaeters
authors: C
authors: C
authors: Duez
authors: J L
authors: JL
authors: Hubinon
authors: M
authors: M
authors: Mommaerts
mesh_terms: D003124:Colorimetry / Q000295:instrumentation* / Q000592:standards; D003880:Dermatology / Q000295:instrumentation / Q000592:standards; D006801:Humans; D012016:Reference Values; D012867:Skin / Q000033:anatomy & histology*; D012871:Skin Diseases / Q000175:diagnosis*