title: Treatment of progressive metastatic glomus jugulare tumor (paraganglioma) with gemcitabine.
abstract: Paragangliomas are rare tumors of the paraganglia composed of specialized neural crest cells arising in association with sympathetic ganglia. Here we report a case of progressive, metastatic paraganglioma (glomus jugulare tumor) responsive to single agent gemcitabine. In addition, a brief review of chemotherapy for paraganglioma follows the case presentation.
authors: Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.
authors: J M
authors: JM
authors: Pipas
authors: R F
authors: RF
authors: Krywicki
mesh_terms: D000293:Adolescent; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology*; D003841:Deoxycytidine / Q000031:analogs & derivatives / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D010235:Paraganglioma / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary*; D014057:Tomography, X-Ray Computed; D000093542:Gemcitabine
chemical_list: D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000093542:Gemcitabine