title: Brief communication: detecting depression: providing high quality primary care for HIV-infected patients.
abstract: Depression is common among HIV-infected patients, but little is known about risk factors for depression in this population. Several studies before protease inhibitors became available have reported inconsistent associations between depression and disease severity. Delivering high quality HIV care includes adequate detection and treatment of depression. The objective of this study was to describe the prevalence and correlates of depression among a contemporary group of HIV-infected patients. The setting and design for the study was a chart abstraction for HIV-infected patients in a primary care practice in Boston, Mass, in June 1997. Among 275 HIV-infected patients, depression was documented in 147 patient charts (53%), half of whom (n = 73, 27%) also received antidepressant medications. We used multivariable logistic regression to identify risk factors for depression among patients with both a chart diagnosis of depression and current antidepressant medication use. We observed increased risk of depression among patients with a history of substance use (odds ratio 2.7, 95% confidence interval 1.5-4.7), recent medical hospitalization (2.6, 1.4-5.0), and homosexual risk behavior (2.1, 1.1-4.2). Depression remains a common problem for HIV-infected patients, particularly among those with history of substance abuse, medical hospitalization, or homosexual risk behavior. Routine screening for depression in this population with special attention to those at higher risk may offer opportunities for earlier diagnosis and treatment.
authors: Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School, Boston, Mass., USA.
authors: K M
authors: KM
authors: Fairfield
authors: H
authors: H
authors: Libman
authors: R B
authors: RB
authors: Davis
authors: D M
authors: DM
authors: Eisenberg
authors: A
authors: A
authors: Beckett
authors: R S
authors: RS
authors: Phillips
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D001900:Boston / Q000453:epidemiology; D003863:Depression / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D003955:Diagnostic Tests, Routine; D005260:Female; D015658:HIV Infections / Q000523:psychology*; D018451:Homosexuality, Male; D006760:Hospitalization; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D015995:Prevalence; D011320:Primary Health Care / Q000592:standards*; D011480:Protease Inhibitors / Q000627:therapeutic use; D012307:Risk Factors; D015819:Substance Abuse, Intravenous
chemical_list: D000928:Antidepressive Agents; D011480:Protease Inhibitors