title: Visceral leishmaniasis in an AIDS patient on successful antiretroviral therapy: failure of parasite eradication despite increase in CD4+ T-cell count but low CD8+ T-cell count.
abstract: An unusual cutaneous relapse of visceral leishmaniasis (initially mistaken for eruptive histiocytomas) was seen in an AIDS patient despite good virological and CD4+ T-cell responses to highly active antiretroviral therapy. Splenectomy and the patient's low CD8+ T-cell count are discussed as possible causes of failed disease control.
authors: Department of Dermatology, University of Innsbruck, Austria.
authors: A
authors: A
authors: Petter
authors: A
authors: A
authors: Shetty-Lee
authors: G
authors: G
authors: Kofler
authors: H P
authors: HP
authors: Huemer
authors: C
authors: C
authors: Larcher
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000469:parasitology*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D018414:CD8-Positive T-Lymphocytes; D003937:Diagnosis, Differential; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy*; D002836:Hemophilia B / Q000150:complications; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000188:drug therapy / Q000209:etiology*; D012008:Recurrence; D013156:Splenectomy; D017211:Treatment Failure