title: Effect of graded running on esophageal motility and gastroesophageal reflux in fed volunteers.
abstract: The effects of different grades of running on esophageal motility and gastroesophageal reflux in the fed state were evaluated. We studied healthy volunteers (male: 12, age: 27 +/- 5 yr) using ambulatory esophageal manometry, pH catheter and portable digital data recorder. Each exercise was performed 30 min after meal, with 20 min of rest between exercises. Subjects exercised on a treadmill at 40% and 70% maximal heart rate. The number of gastroesophageal reflux episodes, the duration of esophageal acid exposure and percent time pH below 4 were significantly (p < 0.01) increased during exercise at 70% maximal heart rate. The frequency of contraction (contraction/min) (p < 0.05), frequency of repetition (p < 0.01), percent of simultaneous contraction (p < 0.01), percent of above 100 mmHg amplitude (p < 0.05), and frequency of 2-peak contraction (p < 0.01) were significantly increased during exercise at 70% maximal heart rate. However, median amplitude and median duration showed no significant changes between each exercise session. Postprandial running exercises induce gastroesophageal reflux, which correlates with exercise intensity. These effects are mediated by disorganized esophageal motility.
authors: Department of Gastroenterology, Wonkwang University School of Medicine, Iksan, Korea.
authors: S C
authors: SC
authors: Choi
authors: K H
authors: KH
authors: Yoo
authors: T H
authors: TH
authors: Kim
authors: S H
authors: SH
authors: Kim
authors: S J
authors: SJ
authors: Choi
authors: Y H
authors: YH
authors: Nah
mesh_terms: D000328:Adult; D004435:Eating; D015154:Esophageal Motility Disorders / Q000209:etiology / Q000503:physiopathology*; D005764:Gastroesophageal Reflux / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D019518:Postprandial Period; D012420:Running