title: Validation of rapid velocity encoded cine imaging of a dynamically complex flow field using turbo block regional interpolation scheme for k space.
abstract: Block regional interpolation scheme for k space (BRISK) is a sparse sampling approach to allow rapid magnetic resonance imaging of dynamic events. Rapid velocity encoded cine (VEC) imaging with Turbo BRISK is potentially an important clinical diagnostic technique for cardiovascular diseases. Previously we applied BRISK and Turbo BRISK to imaging pulsatile flow in a straight tube. To evaluate the capabilities of Turbo BRISK imaging in more complex dynamic flow fields such as might exist in the human vasculature, an in vitro curved tube model, similar in geometry to the aortic arch, was fabricated and imaged under pulsatile flow conditions. Velocity maps were obtained using conventional VEC and Turbo BRISK (turbo factors 1 through 5). Comparison of the flow fields obtained with each higher order turbo factor showed excellent agreement with conventional VEC with minimal loss of information. Similarly, flow maps showed good agreement with the profiles from a laser Doppler velocimetry model. Turbo-5 BRISK, for example, allowed a 94% savings in imaging time, reducing the conventional imaging time from over 8 min to a near breath-hold imaging period of 31 s. Turbo BRISK shows excellent promise toward the development of a clinical tool to evaluate complex dynamic intravascular flow fields.
authors: Computer Science Department, University of New Orleans, LA 70148, USA. eduardo@cs.uno.edu
authors: E
authors: E
authors: Kortright
authors: M
authors: M
authors: Doyle
authors: A S
authors: AS
authors: Anayiotos
authors: E G
authors: EG
authors: Walsh
authors: A R
authors: AR
authors: Fuisz
authors: G M
authors: GM
authors: Pohost
mesh_terms: D001698:Biomedical Engineering; D003198:Computer Simulation; D003326:Coronary Circulation; D006439:Hemodynamics; D006801:Humans; D017078:Laser-Doppler Flowmetry; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008953:Models, Anatomic; D008955:Models, Cardiovascular