Antidiarrhoeal activity of root extracts from Roureopsis obliquifoliolata and Epinetrum villosum.
The methanol extracts of Roureopsis obliquifoliolata and Epinetrum villosum root significantly reduced castor oil-induced diarrhoea in mice. This effect supports the use of these plants in Congolese folk medicine as antidiarrhoeal remedies.
Longanga Otshudi
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Laboratory of Pharmacognosy, Phytochemistry and Toxicology, Department of Pharmaceutical Sciences, Vrije Universiteit Brussel (V.U.B.), Laarbeeklaan 103, B-1090, Brussels, Belgium. olonga@vub.vub.ac.be
Vercruysse
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Foriers
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D000818:Animals; D000930:Antidiarrheals / Q000494:pharmacology* / Q000627:therapeutic use*; D002368:Castor Oil; D003967:Diarrhea / Q000139:chemically induced / Q000517:prevention & control*; D005260:Female; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology; D018517:Plant Roots; D010946:Plants, Medicinal; D019685:Rosales
D000930:Antidiarrheals; D010936:Plant Extracts; D002368:Castor Oil