title: 99Tc(m) nanocolloid scintigraphy: a reliable way to detect active joint disease in patients with peripheral joint pain.
abstract: We evaluated 99Tc(m) nanocolloid (NC) scintigraphy as a method for identifying patients with active joint disease in a group with peripheral joint pain of varying aetiology. Fifty-nine patients with peripheral joint pain were divided into two groups: those with clinical signs of active joint inflammation and those without objective signs. Thirty-four patients clinically diagnosed as having active joint disease had a total of 117 joints (95 large and 22 small) involved. 99Tc(m) NC identified 96 (79 large and 17 small) of these joints. Twenty-five patients were negative clinically. Twenty-two of these were scan negative. The other three had a total of 11 scan positive joints. The correlation coefficient between clinical and scan findings was 0.79. There was no significant difference shown between clinical evaluation and scintigraphy (z=-1.64, P = 0.1004). 99Tc(m) NC proved to be an effective method for identifying patients with active peripheral joint disease from among a group with arthralgia.
authors: Department of Nuclear Medicine, Mafraq Hospital, Abu Dhabi, United Arab Emirates. bruceka@emirates.net.ae
authors: B K
authors: BK
authors: Adams
authors: H M
authors: HM
authors: Al Attia
authors: R A
authors: RA
authors: Khadim
authors: Z Y
authors: ZY
authors: Al Haider
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007249:Inflammation / Q000000981:diagnostic imaging; D007592:Joint Diseases / Q000145:classification / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D008180:Lupus Erythematosus, Systemic / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000000981:diagnostic imaging; D010146:Pain; D011877:Radionuclide Imaging; D015203:Reproducibility of Results; D013668:Technetium Tc 99m Aggregated Albumin / Q000493:pharmacokinetics; D014018:Tissue Distribution
chemical_list: D013668:Technetium Tc 99m Aggregated Albumin; C083602:technetium Tc 99m nanocolloid