title: Application of magnetic resonance imaging to angiogenesis in breast cancer.
abstract: Magnetic resonance imaging (MRI) techniques enable vascular function to be mapped with high spatial resolution. Current methods for imaging in breast cancer are described, and a review of recent studies that compared dynamic contrast-enhanced MRI with histopathological indicators of tumour vascular status is provided. These studies show correlation between in vivo dynamic contrast measurements and in vitro histopathology. Dynamic contrast-enhanced MRI is also being applied to assessment of the response of breast tumours to treatment.
authors: CRC Clinical Magnetic Resonance Research Group, The Institute of Cancer Research and The Royal Marsden NHS Trust, Sutton, Surrey, UK. Martin@icr.ac.uk
authors: M O
authors: MO
authors: Leach
mesh_terms: D000818:Animals; D018952:Antigens, CD34 / Q000032:analysis; D001943:Breast Neoplasms / Q000098:blood supply* / Q000175:diagnosis; D003287:Contrast Media; D016228:Endothelial Growth Factors / Q000032:analysis; D005260:Female; D006801:Humans; D008222:Lymphokines / Q000032:analysis; D008279:Magnetic Resonance Imaging; D008327:Mammography; D051379:Mice; D008819:Mice, Nude; D009389:Neovascularization, Pathologic / Q000175:diagnosis* / Q000000981:diagnostic imaging; D012106:Research; D014183:Transplantation, Heterologous; D014463:Ultrasonography; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
chemical_list: D018952:Antigens, CD34; D003287:Contrast Media; D016228:Endothelial Growth Factors; D008222:Lymphokines; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors