title: Life and death in the JUNgle.
abstract: Experiments with transgenic and knockout mice have begun to elucidate distinct roles for the three members of the Jun family of transcription factors. Mice with tissue-specific loss of JunB develop a myeloproliferative disorder, emphasizing the important roles that Jun proteins play in regulating life and death decisions in disease.
authors: Unité des Virus Oncogènes, Pasteur Institute, 25 Rue du Dr Roux, Paris, France. jonny@pasteur.fr
authors: J B
authors: JB
authors: Weitzman
mesh_terms: D000818:Animals; D017209:Apoptosis; D002455:Cell Division; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D008954:Models, Biological; D009196:Myeloproliferative Disorders / Q000378:metabolism*; D011485:Protein Binding; D016755:Proto-Oncogene Proteins c-jun / Q000502:physiology*
chemical_list: D016755:Proto-Oncogene Proteins c-jun