Creating therapeutic cancer vaccines: notes from the battlefield.
With the identification of tumor antigens and a knowledge of how to vaccinate against them, the field of tumor immunology faces new challenges. In this article, the authors argue that successful immunotherapies of the future will activate anti-tumor T cells without inducing their anergy or apoptotic death.
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D000818:Animals; D019496:Cancer Vaccines / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D016233:Immunotherapy, Active / Q000639:trends*; D051379:Mice; D009369:Neoplasms / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology; D019139:Tumor Escape / Q000276:immunology
D019496:Cancer Vaccines