Confirmation of the retinopetal/centrifugal nature of the tyrosine hydroxylase-immunoreactive fibers of the retina and optic nerve in the weaver mouse.
The number of tyrosine hydroxylase-immunoreactive fibers in the nerve fiber layer is increased in the retina of the weaver compared to control mice (Dev. Brain Res. 121 (2000) 113). To confirm the retinopetal/centrifugal nature of these fibers, a newly devised whole-mounted optic nerve technique allowed us to determine, during development, their first appearance within the optic nerve (post-natal day 12) compared to retina (post-natal day 13). One such fiber was also observed looping in the retina of a monkey fetus.
Simon
A
A
Institut des Neurosciences, Département de Neurobiologie des Signaux Intercellulaires, Université Paris VI, 7 quai Saint Bernard, 75252 cedex 05, Paris, France.
Martin-Martinelli
E
E
Savy
C
C
Verney
C
C
Raisman-Vozari
R
R
Nguyen-Legros
J
J
D000818:Animals; D000906:Antibodies; D051676:G Protein-Coupled Inwardly-Rectifying Potassium Channels; D008252:Macaca fascicularis; D051379:Mice; D008808:Mice, Inbred CBA; D008818:Mice, Neurologic Mutants; D009412:Nerve Fibers / Q000201:enzymology; D009900:Optic Nerve / Q000201:enzymology* / Q000254:growth & development*; D015221:Potassium Channels / Q000235:genetics; D024661:Potassium Channels, Inwardly Rectifying; D012160:Retina / Q000201:enzymology* / Q000254:growth & development*; D014446:Tyrosine 3-Monooxygenase / Q000032:analysis* / Q000276:immunology
D000906:Antibodies; D051676:G Protein-Coupled Inwardly-Rectifying Potassium Channels; D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying; D014446:Tyrosine 3-Monooxygenase