title: Property-based design: optimization of drug absorption and pharmacokinetics.
authors: Department of Drug Metabolism, Pfizer Global Research and Development, Sandwich Laboratories, Sandwich, Kent CT13 9NJ, UK. han_waterbeemd@sandwich.pfizer.com
authors: H
authors: H
authors: van De Waterbeemd
authors: D A
authors: DA
authors: Smith
authors: K
authors: K
authors: Beaumont
authors: D K
authors: DK
authors: Walker
mesh_terms: D000818:Animals; D001692:Biological Transport; D001798:Blood Proteins / Q000378:metabolism; D001812:Blood-Brain Barrier; D018938:Caco-2 Cells; D002462:Cell Membrane / Q000378:metabolism; D015195:Drug Design; D005123:Eye / Q000378:metabolism; D006801:Humans; D007408:Intestinal Absorption; D008954:Models, Biological; D008958:Models, Molecular; D009297:Nasal Mucosa / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010599:Pharmacokinetics; D011355:Prodrugs / Q000378:metabolism; D012869:Skin Absorption
chemical_list: D001798:Blood Proteins; D004364:Pharmaceutical Preparations; D011355:Prodrugs