title: Smart suction device for less blood trauma: a comparison with Cell Saver.
abstract: OBJECTIVE
  The major source of hemolysis during cardiopulmonary bypass remains the cardiotomy suction and is primarily due to the interaction between air and blood. The Smart suction system involves an automatically controlled aspiration designed to avoid the mixture of blood with air. This study was set-up to compare this recently designed suction system to a Cell Saver system in order to investigate their effects on blood elements during prolonged intrathoracic aspiration.
  
  
  METHODS
  In a calf model (n=10; mean weight, 69.3+/-4.5 kg), a standardized hole was created in the right atrium allowing a blood loss of 100 ml/min, with a suction cannula placed into the chest cavity into a fixed position during 6 h. The blood was continuously aspirated either with the Smart suction system (five animals) or the Cell Saver system (five animals). Blood samples were taken hourly for blood cell counts and biochemistry.
  
  
  RESULTS
  In the Smart suction group, red cell count, plasma protein and free hemoglobin levels remained stable, while platelet count exhibited a significant drop from the fifth hour onwards (prebypass: 683+/-201*10(9)/l, 5 h: 280+/-142*10(9)/l, P=0.046). In the Cell Saver group, there was a significant drop of the red cell count from the third hour onwards (prebypass: 8.6+/-0.9*10(12)/l, 6 h: 6.3+/-0.4*10(12)/l, P=0.02), of the platelet count from the first hour onwards (prebypass: 630+/-97*10(9)/l, 1 h: 224+/-75*10(9)/l, P<0.01), and of the plasma protein level from the first hour onwards (prebypass: 61.7+/-0.6 g/l, 1 h: 29.3+/-9.1 g/l, P<0.01).
  
  
  CONCLUSIONS
  In this experimental set-up, the Smart suction system avoids damage to red cells and affects platelet count less than the Cell Saver system which induces important blood cell destruction, as any suction device mixing air and blood, as well as severe hypoproteinemia with its metabolic, clotting and hemodynamic consequences.
authors: Clinic for Cardiovascular Surgery and Surgical Intensive Care Unit, Centre Hospitalier Universitaire Vaudois, CH-1011 Lausanne, Switzerland. xavier.mueller@chuv.hospvd.ch
authors: X M
authors: XM
authors: Mueller
authors: H T
authors: HT
authors: Tevaearai
authors: J
authors: J
authors: Horisberger
authors: M
authors: M
authors: Augstburger
authors: Y
authors: Y
authors: Boone
authors: L K
authors: LK
authors: von Segesser
mesh_terms: D000818:Animals; D001804:Blood Transfusion, Autologous / Q000295:instrumentation*; D002417:Cattle; D004867:Equipment Design; D023421:Models, Animal; D013396:Suction / Q000295:instrumentation*; D014461:Ultracentrifugation / Q000295:instrumentation