Preparation of pentachlorophenol derivatives and development of a microparticle-based on-site immunoassay for the detection of PCP in soil samples.
Pentachlorophenol (PCP) is used as a herbicide in agriculture and as an insecticide for termite control. Because of the apparent hazard associated with its usage, there is a need for an efficient and economic on-site screening method. A 5-min on-site test has been developed for the detection of PCP based on the OnTrak format, a successful Roche on-site test format for drugs of abuse, utilizing the principle of latex agglutination immunoassay. The test detects 1 ppm of PCP in soil samples.
Li
M
M
Roche Diagnostics Corporation, 9115 Hague Road, Indianapolis, IN 46250, USA.
Tsai
S F
SF
Rosen
S M
SM
Wu
R S
RS
Reddy
K B
KB
DiCesare
J
J
Salamone
S J
SJ
D000372:Agglutination Tests / Q000379:methods; D000818:Animals; D007118:Immunoassay / Q000379:methods; D020049:Isoptera; D010416:Pentachlorophenol / Q000032:analysis*; D010571:Pest Control / Q000379:methods; D010573:Pesticide Residues / Q000032:analysis*; D010575:Pesticides / Q000032:analysis*; D012989:Soil Pollutants / Q000032:analysis*
D010573:Pesticide Residues; D010575:Pesticides; D012989:Soil Pollutants; D010416:Pentachlorophenol