Polymer-supported triazole and benzotriazole leaving groups. Three new examples and a comparison of their efficiency.
Three polymer-supported heterocyclic (triazole 4 and benzotriazoles 2, 8) leaving groups are described. The loading of 8 was clearly superior to those of 2 and 4. The efficiency of 8 was higher than those of previously reported benzotriazole resins 9a,b in the C-acylation of ketones.
Katritzky
A R
AR
Department of Chemistry, Center for Heterocyclic Compounds, University of Florida, Gainesville, Florida 32611-7200, USA.
Pastor
A
A
Voronkov
M
M
Tymoshenko
D
D