title: Case study: sexual hyperactivity treated with psychostimulants in familial male precocious puberty.
abstract: Familial male precocious puberty is a form of precocious puberty resulting from an activating mutation of the luteinizing hormone receptor. Behavior problems are associated with the early onset of puberty. In this case, sexual hyperactivity was treated with psychostimulants. Implications for the effectiveness of methylphenidate in reducing sexual hyperactivity with and without familial male precocious puberty are discussed, and testable hypotheses are proposed for the effects of stimulants on sexual behavior in adolescents.
authors: National Institute of Mental Health, Bethesda, MD 20814-1276, USA.
authors: A A
authors: AA
authors: Weissenberger
authors: E W
authors: EW
authors: Leschek
authors: A J
authors: AJ
authors: Zametkin
mesh_terms: D000697:Central Nervous System Stimulants / Q000494:pharmacology* / Q000627:therapeutic use; D002675:Child, Preschool; D006801:Humans; D008297:Male; D008774:Methylphenidate / Q000494:pharmacology* / Q000627:therapeutic use; D011629:Puberty, Precocious / Q000235:genetics* / Q000523:psychology*; D012725:Sexual Behavior / Q000187:drug effects / Q000523:psychology*; D020018:Sexual Dysfunctions, Psychological / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000697:Central Nervous System Stimulants; D008774:Methylphenidate