Pyrone and pyridone compounds in the liquid culture of Physisporinus sanguinolentus.
Chromatographic separation of the liquid culture filtrate of the basidiomycete fungus Physisporinus sanguinolentus has yielded three new compounds viz., 2-methyl-4-pyrone, 2-methyl-5,6-dihydro-4-pyrone and the pyridone form of 4-hydroxy-2-methylpyridine, together with the known triacetic acid lactone, the sesquiterpene dialdehyde merulidial and a derivative of merulidial. Their structures were elucidated by spectroscopic analysis and by comparison to literature data and a synthetic sample. One of the compounds, merulidial, was shown to inhibit the germination of spores and the hyphal growth of the wood-rotting basidiomycete Heterobasidion annosum and the saprophytic mould Cladosporium cucumerinum.
Svensson
M
M
epartment of Chemistry, Swedish University of Agricultural Sciences, Uppsala.
Lundgren
L N
LN
Woods
C
C
Fatehi
J
J
Stenlid
J
J
D002851:Chromatography, High Pressure Liquid; D003470:Culture Media; D011124:Polyporaceae / Q000502:physiology*; D011728:Pyridones / Q000032:analysis* / Q000737:chemistry; D011753:Pyrones / Q000032:analysis* / Q000737:chemistry
D003470:Culture Media; D011728:Pyridones; D011753:Pyrones