title: Contribution of erythrocytes and plasma in threonine and lysine transfer across the portal drained viscera and the liver in pigs. Effect of threonine and lysine dietary supply.
abstract: Contributions of erythrocytes and plasma to threonine and lysine transport across the PDV and the liver were determined in growing pigs successively fed a threonine deficient diet and a control well-balanced diet (experiment 1) or a lysine deficient or a well-balanced diet (experiment 2). The animals were surgically prepared for insertion of chronic catheters in the mesenteric vein (MV), the portal vein (PV), a hepatic vein (HV) and the carotid artery (CA). Plasma and whole blood AA concentrations in PV, HV and CA and PV and HV blood flows were determined during 6 hours of para-aminohippuric acid constant infusion. During this period the pigs were continuously fed (1 meal per hour). The contribution of plasma to lysine and threonine transport was higher in pigs fed the well balanced diets. More than 50% of threonine and lysine appearing in the PV and in the HV are transported by the plasma. Our results suggest that erythrocytes are probably little involved in lysine and threonine transfer across the liver and digestive tract of pig continuously fed.
authors: Unité Mixte de Recherches sur le Veau et le Porc, INRA, Saint-Gilles, France. lefloch@st-gilles.rennes.inra.fr
authors: N
authors: N
authors: Le Floc'h
authors: L
authors: L
authors: Lahaye
authors: N
authors: N
authors: Mézière
authors: B
authors: B
authors: Sève
mesh_terms: D000818:Animals; D001692:Biological Transport; D002339:Carotid Arteries; D002404:Catheterization / Q000662:veterinary; D004032:Diet / Q000662:veterinary; D004912:Erythrocytes / Q000502:physiology*; D005260:Female; D006503:Hepatic Veins; D008099:Liver / Q000378:metabolism*; D008239:Lysine / Q000097:blood*; D008642:Mesenteric Veins; D011168:Portal System / Q000502:physiology*; D011169:Portal Vein; D013552:Swine / Q000097:blood* / Q000378:metabolism; D013912:Threonine / Q000097:blood*; D010130:p-Aminohippuric Acid
chemical_list: D013912:Threonine; D008239:Lysine; D010130:p-Aminohippuric Acid