title: Ticlopidine-induced hepatitis.
abstract: Ticlopidine is a commonly prescribed drug in cerebrovascular or cardiovascular diseases. Since the first introduction in 1970's, ticlopidine was shown to be a relatively safe drug. The adverse effects of ticlopidine were mainly bone marrow toxicity and elevation of liver function tests. Ticlopidine-induced hepatitis is rare and only 33 cases were reported in previous English literature. The 33 cases were mostly categorized in cholestatic liver injury; only 2 cases were hepatocellular. In Taiwan, a case of ticlopidine-induced cholestatic hepatitis was ever reported. Herein, we present another rare case of ticlopidine-induced hepatitis in Taiwan with the nature of hepatocellular injury.
authors: Department of Family Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
authors: L K
authors: LK
authors: Chen
authors: B H
authors: BH
authors: Hsieh
authors: W C
authors: WC
authors: Chen
authors: S T
authors: ST
authors: Tsai
authors: M C
authors: MC
authors: Hou
mesh_terms: D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D006801:Humans; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*; D013988:Ticlopidine / Q000009:adverse effects*
chemical_list: D010975:Platelet Aggregation Inhibitors; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D013988:Ticlopidine