title: Reproducibility of antroduodenal motility during prolonged ambulatory recording.
abstract: Ambulatory recording of antroduodenal manometry is a novel technique with several advantages over standard stationary manometry recording. Although the feasibility of this technique in clinical practice has been demonstrated, reproducibility of antroduodenal motility recorded by means of ambulatory manometry has not been investigated. To test whether antroduodenal motility recorded by ambulatory manometry is reproducible, we performed two 24-h ambulatory antroduodenal manometry recordings in 18 healthy subjects according to an identical protocol with a 1-week interval. Motility was recorded with a five-channel solid-state catheter. Postprandial motility was recorded after consumption of two test meals and interdigestive motility was recorded nocturnally. Postprandial antroduodenal motor characteristics were identical between the separate recordings. The number and duration of nocturnal cycles of the interdigestive migrating motor complex were also in the same range. Phase III characteristics in general were not different between the two recordings. Only minor alterations were observed in the duration of phase III motor fronts with duodenal onset and in the number of interdigestive cycles concluded by duodenal onset phase III. Parameters obtained by qualitative analysis were comparable between the two recordings. The antroduodenal motility pattern, when measured by ambulatory recording with solid state catheters under standardized conditions, is very reproducible.
authors: Department of Gastroenterology-Hepatology, Leiden University Medical Centre, The Netherlands.
authors: C
authors: C
authors: Penning
authors: H A
authors: HA
authors: Gielkens
authors: M
authors: M
authors: Hemelaar
authors: C B
authors: CB
authors: Lamers
authors: A A
authors: AA
authors: Masclee
mesh_terms: D000328:Adult; D004063:Digestion / Q000502:physiology; D004386:Duodenum / Q000502:physiology*; D005260:Female; D005769:Gastrointestinal Motility / Q000502:physiology*; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods* / Q000592:standards*; D008875:Middle Aged; D019518:Postprandial Period; D011706:Pyloric Antrum / Q000502:physiology*; D015203:Reproducibility of Results; D016138:Walking