Hemiparetic cerebral palsy: etiological risk factors and neuroimaging.
The purpose of this paper, which was conducted on 175 children with hemiparetic cerebral palsy (H-CP), was to verify the etiological risk period for this disease. Etiological risk factors (ERF) were detected through anamnesis: 23% in the prenatal period, 18% in the perinatal period and 59% of the patients the period was undefined (ERF in the prenatal and perinatal period was 41% and no ERF was 18% of the cases. The computerized tomographic scan (CT) and MRI were performed on all the patients, who were then classified according to their etiopathogenic data: CT1= normal (18%); CT 2= unilateral ventricular enlargement (25%); CT 3= cortical/ subcortical cavities (28%); CT4= hemispheric atrophy and other findings (14%); CT 5= malformations (15%). CT 5 was associated with physical malformations beyond the central nervous system and with prenatal ERF's, while CT 2 was associated with the perinatal ERF's, mainly in premature births. Magnetic resonance imaging was performed on 57 patients and demonstrated a good degree of concordance with the CT. Etiology remained undefined in only 37% of the cases after neuroimaging was related to ERF. A high perinatal RF frequency (59%) was observed and emphasized the need for special care during this period.
Piovesana
A M
AM
Pediatric Neurology Division, Department of Neurology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil. piovesag@fcm.unicamp.br
Moura-Ribeiro
M V
MV
Zanardi Vd
Gonçalves
V M
VM
D002547:Cerebral Palsy / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010291:Paresis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012044:Regression Analysis; D012307:Risk Factors; D014057:Tomography, X-Ray Computed