Experimental study of phosphopeptide in promoting tooth remineralization.
OBJECTIVE
To explore a new method for effective and safe prevention and treatment of caries.


METHODS
Following the theory of tooth remineralization, we searched for the mechanism and clinical application of tooth remineralization with phosphopeptide.


RESULTS
Phosphopeptide, with calcium and phosphorus, had a high affinity for hydroxyapatite and could enhance tooth remineralization.


CONCLUSIONS
Phosphopeptide was effective in the prevention and treatment of tooth decay. Clinically, it could be safely applied.
Zhang
L
L
Shenyang Stomatological Hospital, Shenyang, Liaoning Province, 110002, P.R. China.
Li
Z
Z
Dong
Y
Y
D000818:Animals; D002130:Calcium Phosphates / Q000737:chemistry / Q000627:therapeutic use; D002327:Cariostatic Agents / Q000627:therapeutic use*; D011232:Chemical Precipitation; D003731:Dental Caries / Q000517:prevention & control; D003743:Dental Enamel / Q000187:drug effects / Q000648:ultrastructure; D004037:Diet, Cariogenic; D017886:Durapatite / Q000737:chemistry; D005260:Female; D006244:Hardness; D006801:Humans; D008859:Microscopy, Polarization; D010710:Phosphates / Q000737:chemistry; D010750:Phosphoproteins / Q000737:chemistry / Q000627:therapeutic use*; D017680:Potassium Compounds / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley; D012995:Solubility; D017001:Tooth Demineralization / Q000517:prevention & control; D014089:Tooth Remineralization; D014100:Toothpastes / Q000627:therapeutic use
D002130:Calcium Phosphates; D002327:Cariostatic Agents; D010710:Phosphates; D010750:Phosphoproteins; D017680:Potassium Compounds; D014100:Toothpastes; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; D017886:Durapatite; C020243:calcium phosphate; C013216:potassium phosphate; C485829:calcium phosphate, dibasic, anhydrous