title: Syphilis outbreak assessment.
abstract: BACKGROUND
  Syphilis rates began to decline in 1991 and have decreased every year since. In 1998, 6,993 cases of primary and secondary syphilis were reported in the United States, for a national incidence of 2.6 cases per 100,000 population. Although syphilis rates are at an historic low, focal outbreaks still occur. On October 7, 1999, the Division of Sexually Transmitted Disease Prevention of the Centers for Disease Control and Prevention, in collaboration with federal and community partners, presented the National Plan for Elimination of Syphilis from the United States. One of the five key strategies of the plan is rapid outbreak response.
  
  
  METHODS
  Methods for outbreak assessment and response were reviewed in the literature, synthesized, and adapted for use in syphilis outbreaks.
  
  
  RESULTS
  Key elements of outbreak assessment and response are detection, surveillance data review, hypothesis generation, intervention development, and the evaluation of clinical, public health, and laboratory services.
  
  
  CONCLUSIONS
  Outbreak response necessitates community participation and a coordinated interdisciplinary effort to determine social and behavioral contributors to the outbreak and to develop targeted interventions.
authors: Epidemiology and Surveillance Branch, Division of STD Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
authors: L
authors: L
authors: Finelli
authors: W C
authors: WC
authors: Levine
authors: J
authors: J
authors: Valentine
authors: M E
authors: ME
authors: St Louis
mesh_terms: D002487:Centers for Disease Control and Prevention, U.S.; D004196:Disease Outbreaks; D006801:Humans; D015994:Incidence; D011159:Population Surveillance / Q000379:methods; D013587:Syphilis / Q000453:epidemiology* / Q000517:prevention & control*; D014481:United States / Q000453:epidemiology