Sensory perineuritis presented as a mononeuritis multiplex associated with livedo vasculitis.
We report a 52-year-old patient affected by a mononeuritis multiplex and livedo vasculitis. Sural nerve biopsy showed mild thickening of the perineurium, vascular alterations with inflammatory cell infiltration in the perineurium, and remarkable loss of large and small myelinated fibers. A therapeutic trial of acetylsalicylic acid, danazol, and dipyridamole controlled the skin lesion without improvement of nerve conduction studies.
Lee
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SS
Department of Neurology and Department of Dermatology, Chungbuk National University Hospital, Gaeshin-dong 62 Heungduk-ku, Cheongju-si, 361-711, Chungbuk, South Korea. sslee@med.chungbuk.ac.kr
Yoon
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D045930:Anabolic Agents / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D001706:Biopsy; D003613:Danazol / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004176:Dipyridamole / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008875:Middle Aged; D020422:Mononeuropathies / Q000209:etiology*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D017445:Skin Diseases, Vascular / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D013497:Sural Nerve / Q000473:pathology*; D016896:Treatment Outcome
D045930:Anabolic Agents; D010975:Platelet Aggregation Inhibitors; D004176:Dipyridamole; D003613:Danazol; D001241:Aspirin