Confidence bands for cumulative incidence curves under the additive risk model.
In the context of competing risks, the cumulative incidence function is often used to summarize the cause-specific failure-time data. As an alternative to the proportional hazards model, the additive risk model is used to investigate covariate effects by specifying that the subject-specific hazard function is the sum of a baseline hazard function and a regression function of covariates. Based on such a formulation, we present an approach to constructing simultaneous confidence intervals for the cause-specific cumulative incidence function of patients with given risk factors. A melanoma data set is used for the purpose of illustration.
Shen
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Department of Biomathematics, M. D. Anderson Cancer Center, University of Texas, Houston 77030, USA. yushen@odin.mdacc.tmc.edu
Cheng
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SC
D000328:Adult; D000368:Aged; D001699:Biometry; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data*; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000401:mortality / Q000473:pathology; D008875:Middle Aged; D015233:Models, Statistical; D016016:Proportional Hazards Models; D012306:Risk; D017211:Treatment Failure