title: Prevalence of low bone density in women with developmental disabilities.
abstract: This study was designed to assess the prevalence and severity of low bone mineral density in an institutionalized population of postmenopausal women (n = 79) with developmental disabilities, using quantitative ultrasound of the calcaneus. The results demonstrate that this population has a significantly lower quantitative ultrasound index (QUI) of the calcaneus compared with a referent population of age-matched control subjects without mental disabilities. We used the QUI T-score threshold of <-2.0 standard deviations (SDs) to define individuals at high risk for osteoporosis, and 82% of the study participants met this criterion. Furthermore, approx 43% of the population had a heel QUI that was more than 2 SDs below that of age-matched control subjects, consistent with a severe degree of demineralization.
authors: Sharon OB-Gyn Associates, 50 Amenia Road, Sharon, CT 06069, USA.
authors: J S
authors: JS
authors: Jaffe
authors: A M
authors: AM
authors: Timell
authors: B I
authors: BI
authors: Gulanski
mesh_terms: D001321:Autistic Disorder / Q000453:epidemiology*; D002111:Calcaneus / Q000000981:diagnostic imaging / Q000503:physiopathology; D002547:Cerebral Palsy / Q000453:epidemiology*; D015897:Comorbidity; D006801:Humans; D008607:Intellectual Disability / Q000453:epidemiology*; D008875:Middle Aged; D009518:New York / Q000453:epidemiology; D015663:Osteoporosis, Postmenopausal / Q000453:epidemiology*; D015995:Prevalence; D014463:Ultrasonography