Vasopressin and blood pressure support for pancreatitis-induced systemic inflammatory response syndrome with circulatory shock.
A 54-year-old patient, admitted to the intensive care unit with a diagnosis of severe pancreatitis, developed circulatory shock that failed to respond to standard vasopressor treatment: epinephrine and norepinephrine. Addition of vasopressin helped reduce standard catecholamine need while maintaining adequate arterial blood pressure. Vasopressin appears to be a promising agent for maintaining arterial pressure during septic shock or systemic inflammatory response syndrome, but due to limited data and potential side effects, its use as first-line treatment for these indications is not recommended.
Lamarre
P
P
Department of Pharmacy, Centre Hospitalier Universitaire de Sherbrooke, Quebec, Canada. patlamarre@Hotmail.com
Perreault
B
B
Lesur
O
O
D001794:Blood Pressure / Q000187:drug effects; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D010195:Pancreatitis / Q000150:complications*; D012769:Shock / Q000150:complications / Q000188:drug therapy*; D018746:Systemic Inflammatory Response Syndrome / Q000150:complications / Q000188:drug therapy* / Q000209:etiology; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*; D014667:Vasopressins / Q000627:therapeutic use*
D014662:Vasoconstrictor Agents; D014667:Vasopressins