title: Pulmonary granular cell tumor coexisting with bronchogenic carcinoma.
abstract: Pulmonary granular cell tumors (GCTs) are uncommon and predominantly benign. The coexistence of GCTs with bronchogenic carcinoma is rare. We report three cases of GCT occurring simultaneously with a primary bronchogenic carcinoma. In one case mucoepidermoid carcinoma was seen colliding with a bronchial submucosal GCT. In another case an endobronchial GCT was seen beneath squamous cell carcinoma in situ and adjacent to invasive squamous carcinoma. In the third case a central bronchial GCT was identified concurrently with a peripheral adenocarcinoma. We suggest that the presence of a GCT should prompt adequate sampling to rule out the coexistence of bronchogenic carcinoma. Clinical awareness and complete evaluation for a malignant primary lung tumor will lead to more appropriate therapy. Ann Diagn Pathol 5:74-79, 2001.
authors: Department of Pathology, University of Tennessee, Memphis, TN 38163, USA.
authors: R T
authors: RT
authors: Cutlan
authors: M
authors: M
authors: Eltorky
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery; D000328:Adult; D002283:Carcinoma, Bronchogenic / Q000473:pathology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery; D005260:Female; D016586:Granular Cell Tumor / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000601:surgery; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000601:surgery