Superovulation and intrauterine insemination in cases of treated mild pelvic disease.
OBJECTIVE
Our purpose was to examine the effect of treated mild pelvic disease on the outcome of superovulation with intrauterine insemination (SO/IUI).


METHODS
Three hundred cycles of SO/IUI were retrospectively reviewed for 118 women with laparoscopically treated minimal/mild endometriosis and 67 cycles for 28 women with minimal/mild distal tubal disease/adnexal adhesions and compared with 265 cycles in 111 couples with idiopathic infertility.


RESULTS
The monthly fecundity rate (MFR) of 6.8% and live birth rate (LBR) of 6% in the endometriosis group were significantly lower (P = 0.002) than those in the idiopathic infertility group (MFR = 13.5%, LBR = 12.1%). The 10.9% MFR and 7.5% LBR in the minimal/mild tubal/adnexal disease were not significantly different from those in the other two groups.


CONCLUSIONS
MFR and LBR were higher after SO/IUI in idiopathic infertility compared to those for treated mild/minimal endometriosis or mild/minimal tubal/adnexal adhesions. However, SO/IUI still remains a reasonable option for both these groups prior to IVF-ET.
Singh
M
M
Center for Advanced Research in Human Reproduction and Infertility, Urological Institute and Department of Gynecology-Obstetrics, Cleveland Clinic Foundation, 9500 Euclid Avenue, A81, Cleveland, Ohio 44195, USA.
Goldberg
J
J
Falcone
T
T
Nelson
D
D
Pasqualotto
E
E
Attaran
M
M
Agarwal
A
A
D000291:Adnexal Diseases / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D000328:Adult; D004715:Endometriosis / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007317:Insemination, Artificial, Homologous / Q000379:methods*; D016015:Logistic Models; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D013480:Superovulation / Q000502:physiology*