title: Superovulation and intrauterine insemination in cases of treated mild pelvic disease.
abstract: OBJECTIVE
  Our purpose was to examine the effect of treated mild pelvic disease on the outcome of superovulation with intrauterine insemination (SO/IUI).
  
  
  METHODS
  Three hundred cycles of SO/IUI were retrospectively reviewed for 118 women with laparoscopically treated minimal/mild endometriosis and 67 cycles for 28 women with minimal/mild distal tubal disease/adnexal adhesions and compared with 265 cycles in 111 couples with idiopathic infertility.
  
  
  RESULTS
  The monthly fecundity rate (MFR) of 6.8% and live birth rate (LBR) of 6% in the endometriosis group were significantly lower (P = 0.002) than those in the idiopathic infertility group (MFR = 13.5%, LBR = 12.1%). The 10.9% MFR and 7.5% LBR in the minimal/mild tubal/adnexal disease were not significantly different from those in the other two groups.
  
  
  CONCLUSIONS
  MFR and LBR were higher after SO/IUI in idiopathic infertility compared to those for treated mild/minimal endometriosis or mild/minimal tubal/adnexal adhesions. However, SO/IUI still remains a reasonable option for both these groups prior to IVF-ET.
authors: Center for Advanced Research in Human Reproduction and Infertility, Urological Institute and Department of Gynecology-Obstetrics, Cleveland Clinic Foundation, 9500 Euclid Avenue, A81, Cleveland, Ohio 44195, USA.
authors: M
authors: M
authors: Singh
authors: J
authors: J
authors: Goldberg
authors: T
authors: T
authors: Falcone
authors: D
authors: D
authors: Nelson
authors: E
authors: E
authors: Pasqualotto
authors: M
authors: M
authors: Attaran
authors: A
authors: A
authors: Agarwal
mesh_terms: D000291:Adnexal Diseases / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D000328:Adult; D004715:Endometriosis / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007317:Insemination, Artificial, Homologous / Q000379:methods*; D016015:Logistic Models; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D013480:Superovulation / Q000502:physiology*