title: Interface between titanium miniplate/screw and human calvaria.
abstract: This study demonstrates interfacial changes of titanium miniplate/screw with normal calvaria and nonvascularized calvarial bone graft ensued from craniectomy in a 53-year-old female. In 18 months after operation, a right parietal bone containing an L-shaped miniplate with screws, 5 mm long and 2 mm in external diameter, was harvested, fixed, and embedded in methylmetacrylate. Fifteen micrometer thick sections were made by an EXAKT cutting-grinding system (Exakt Company, Hamburg, Germany), and reviewed under the bright field light microscope. The mean of the bone-contacting surface ratio (BCSR) in six screwed bone was 64.1%; 69.3% in normal bone, and 60.4% in grafted bone. The trabecular bone areas in 10 x 5 mm (50 mm2) rectangular area of diploe surrounding the screws was 43.02 mm2; 45.25 mm2 in normal calvaria; and 41.82 mm2 in grafted bone. The mean Ca/P peak-height ratio of the plated and screwed calvaria was 1.47 in a 9 mm wide zone around each screw; 1.37 in normal calvaria; and 1.51 in grafted calvaria. We concede that the effect of direct contact of titanium with screws onto the bone is as much as an osseous integration (osseointegration).
authors: Department of Plastic Surgery, Inha University Hospital, 7-206 Shinheung-dong, Choong-gu, Inchon, 400-103, Korea. jokerhg@inha.ac.kr
authors: K
authors: K
authors: Hwang
authors: J M
authors: JM
authors: Schmitt
authors: J O
authors: JO
authors: Hollinger
mesh_terms: D001860:Bone Plates; D001863:Bone Screws; D016025:Bone Transplantation / Q000295:instrumentation*; D001932:Brain Neoplasms / Q000601:surgery; D003399:Craniotomy / Q000295:instrumentation*; D004577:Electron Probe Microanalysis; D005260:Female; D006801:Humans; D008852:Microradiography; D008875:Middle Aged; D016348:Osseointegration; D010296:Parietal Lobe / Q000601:surgery; D012886:Skull / Q000601:surgery; D014025:Titanium
chemical_list: D014025:Titanium