Nitroimidazole-resistant vaginal trichomoniasis treated with paromomycin.
A 33-year old woman with nitroimidazole-resistant vaginal trichomoniasis is described. She was treated with intravaginal paromomycin (500 mg daily for 2 days). This cured the trichomoniasis but resulted in severe local side effects. Paromomycin may be useful for difficult cases of nitroimidazole-resistant Trichomonas vaginalis vaginitis. The exact dosage still has to be determined.
Poppe
W A
WA
Department of Gynaecology, University Hospital Gasthuisberg, Catholic University Leuven, Herestraat 49, B-3000, Leuven, Belgium. willy.poppe@uz.kuleven.ac.be
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009593:Nitroimidazoles / Q000627:therapeutic use*; D010303:Paromomycin / Q000627:therapeutic use*; D017211:Treatment Failure; D014247:Trichomonas Vaginitis / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D009593:Nitroimidazoles; D010303:Paromomycin