title: Alkyl phenols and derivatives from Tapirira obtusa.
abstract: From the bark of Tapiria obtusa, six alkyl phenol derivatives were isolated: 1-hydroxy-3-[(Z)-7'-nonadecenyl]-benzene, 1-hydroxy-3-[(Z)-7'-heptadecenyl]-benzene, 1-hydroxy-3-[14'-phenyltetradecyl]-benzene, and 1-hydroxy-3-[16'-phenyltetradecyl]-benzene, and their possible biogenetic precursors, 1-(16'-phenyl-12'Z-hexadecenyl)-4-Z-cyclohexene-(1S*,3S*)-diol and (4S*,6S*)-dihydroxy-6-(14'Z-nonadecenyl)-2-cyclohexenone. The structures of these compounds were elucidated by chemical and spectroscopic analysis, (4S*,6S*)-Dihydroxy-6-(14'Z-nonadecenyl)-2-cyclohexenone showed cytotoxic activity.
authors: College of Pharmacy, University of Illinois at Chicago, 60612, USA.
authors: S D
authors: SD
authors: Correia
authors: J M
authors: JM
authors: David
authors: J P
authors: JP
authors: David
authors: H B
authors: HB
authors: Chai
authors: J M
authors: JM
authors: Pezzuto
authors: G A
authors: GA
authors: Cordell
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification; D018547:Plant Stems / Q000737:chemistry; D019685:Rosales / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D014197:Trees
chemical_list: D010636:Phenols