Hypertrichosis lanuginosa acquisita preceding extraskeletal Ewing's sarcoma.
A 62-year-old woman with acquired hypertrichosis lanuginosa as a paraneoplastic presenting sign of an extraskeletal Ewing's sarcoma is described. Despite initial comprehensive screening to rule out an associated malignancy, a definitive diagnosis of sarcoma was established only 1 year after the onset of the cutaneous symptoms. To the best of our knowledge, this is the first report of hypertrichosis lanuginosa acquisita associated with a soft tissue sarcoma. Our observation expands the spectrum of malignancies associated with this uncommon paraneoplastic disorder.
Pérez-Losada
E
E
Department of Dermatology, Hospital de la Santa Creu i Sant Pau. Hospital del Mar, IMAS, Barcelona, Spain.
Pujol
R M
RM
Domingo
P
P
Matias-Guiu
X
X
Lenti
J
J
López-Pousa
A
A
Alomar
A
A
D005260:Female; D006801:Humans; D006983:Hypertrichosis; D008875:Middle Aged; D010257:Paraneoplastic Syndromes; D010386:Pelvic Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D012512:Sarcoma, Ewing / Q000150:complications* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed