title: A study of infectious intestinal disease in England: risk factors associated with group A rotavirus in children.
abstract: OBJECTIVE
  To identify risk factors for infectious intestinal disease (IID) due to rotavirus group A in children aged under 16 years.
  
  
  METHODS
  Case-control study of cases of IID with rotavirus infection presenting to general practitioners (GPs) or occurring in community cohorts, and matched controls.
  
  
  RESULTS
  There were 139 matched pairs. In children under 16 years the following risk factors were significantly associated with rotavirus IID: living in rented council housing (adjusted OR = 3.78, P = 0.022), accommodation with more than five rooms (OR = 0.72, P = 0.002), contact with someone ill with IID (OR = 3.45, P < 0.001). Some foods were associated with decreased risk. In infants, bottle feeding with or without breast feeding was associated with increased risk (OR = 9.06, P < 0.05).
  
  
  CONCLUSIONS
  Contact with persons with IID, living in rented council housing and accommodation with fewer rooms, were significant risk factors for sporadic rotavirus IID in children whereas breast feeding is protective in infants.
authors: London School of Hygiene and Tropical Medicine, England, UK.
authors: D
authors: D
authors: Sethi
authors: P
authors: P
authors: Cumberland
authors: M J
authors: MJ
authors: Hudson
authors: L C
authors: LC
authors: Rodrigues
authors: J G
authors: JG
authors: Wheeler
authors: J A
authors: JA
authors: Roberts
authors: D S
authors: DS
authors: Tompkins
authors: J M
authors: JM
authors: Cowden
authors: P J
authors: PJ
authors: Roderick
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D001903:Bottle Feeding; D001942:Breast Feeding; D016022:Case-Control Studies; D002648:Child; D002656:Child Day Care Centers; D002675:Child, Preschool; D015331:Cohort Studies; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000821:virology; D004739:England / Q000453:epidemiology; D005243:Feces / Q000821:virology*; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology / Q000821:virology; D005767:Gastrointestinal Diseases / Q000453:epidemiology* / Q000821:virology; D006798:Housing; D006801:Humans; D007223:Infant; D008297:Male; D012307:Risk Factors; D012401:Rotavirus / Q000145:classification / Q000302:isolation & purification; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000821:virology; D011795:Surveys and Questionnaires