Solid-phase synthesis of 2,4-diaminoquinazolines.
A highly efficient and versatile solid-phase synthesis of 2,4-diaminoquinazoline library from 2,4-dichloroquinazolines and amines using 3,5-dimethoxy 4-formylphenoxy-polystyrene resin is described.
Wu
Z
Z
3-Dimensional Pharmaceuticals, Inc., Eagleview Corporate Center, Exton, Pennsylvania 19341, USA.
Kim
J
J
Soll
R M
RM
Dhanoa
D S
DS
D020650:Combinatorial Chemistry Techniques; D009682:Magnetic Resonance Spectroscopy; D011799:Quinazolines / Q000737:chemistry*
D011799:Quinazolines; C013474:2,4-diaminoquinazoline