title: Invading basal cell carcinoma of the jaw: an under-evaluated complex entity.
abstract: Basal cell carcinoma (BCC) is a locally invasive neoplasm, rarely metastatic, yet capable of significant local destruction and disfigurement. Invasion into the bone is uncommon and only a few cases of invasion into facial bones, but never to the mandible or maxilla, have been described. We report three patients with BCC lesions invading their jaws, as a consequence of which either their mandible or maxilla had to be partially resected. This resulted in facial mutilation which required comprehensive multi-disciplinary therapy to restore function and esthetics. Such therapy requires a combination of modalities offered by both plastic and maxillofacial surgeons, as well as oral and dental rehabilitators.
authors: Department of Oral and Maxillofacial Surgery, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. nagler@tx.technion.ac.il
authors: R M
authors: RM
authors: Nagler
authors: D
authors: D
authors: Laufer
mesh_terms: D000328:Adult; D000368:Aged; D000382:Agricultural Workers' Diseases / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D016025:Bone Transplantation; D002280:Basal Cell Carcinoma / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D002281:Carcinoma, Basosquamous / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D002610:Cheek; D002680:Chin; D015921:Dental Implants; D018450:Disease Progression; D005153:Facial Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology / Q000556:secondary; D037981:Neck Dissection; D009361:Neoplasm Invasiveness / Q000473:pathology*; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D009378:Neoplasms, Multiple Primary; D009381:Neoplasms, Radiation-Induced / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D009784:Occupational Diseases / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D019651:Plastic Surgery Procedures; D013177:Sports; D013472:Sunlight / Q000009:adverse effects; D013524:Surgical Flaps
chemical_list: D015921:Dental Implants