title: Glansectomy: an alternative surgical treatment for Buschke-Löwenstein tumors of the penis.
abstract: OBJECTIVE
  To present the surgical excision of the glans penis (glansectomy) as an alternative surgical treatment to penectomy. Buschke-Löwenstein tumors of the penis include the entities described in published reports as verrucous carcinoma and giant condyloma acuminatum of the penis. Both types are well-differentiated tumors, typically confined to the glans penis, with distinctly rare metastatic activity.
  
  
  METHODS
  The study included 7 patients, 40 to 63 years of age, with exophytic, papillary lesions involving the glans penis. Biopsy led to the diagnosis of verrucous carcinoma in 4 patients and giant condyloma acuminatum in 3 patients. All patients reported normal erectile function. Because of the low malignant potential of the tumor and its confinement to the glans penis, a simple glansectomy was performed in all patients to preserve the maximal penile length and functional integrity of the corpora cavernosa.
  
  
  RESULTS
  The postoperative course was uncomplicated. With 18 to 65 months of follow-up, all patients were disease free. One patient required more aggressive treatment because of local recurrence of the tumor. All patients returned to normal sexual activity 1 month postoperatively. The only change during sexual activity, noted by two of the patients' partners, was vaginal pain, possibly due to the absence of the glans.
  
  
  CONCLUSIONS
  Glansectomy may be considered the treatment of choice in patients with Buschke-Löwenstein tumors of the penis, with more radical techniques reserved for second-line treatment.
authors.affiliation: Department of Urology, Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece.
authors.forename: D G
authors.initials: DG
authors.lastname: Hatzichristou
authors.forename: A
authors.initials: A
authors.lastname: Apostolidis
authors.forename: V
authors.initials: V
authors.lastname: Tzortzis
authors.forename: K
authors.initials: K
authors.lastname: Hatzimouratidis
authors.forename: E
authors.initials: E
authors.lastname: Ioannides
authors.forename: K
authors.initials: K
authors.lastname: Yannakoyorgos
mesh_terms: D000328:Adult; D018289:Carcinoma, Verrucous / Q000473:pathology / Q000601:surgery*; D003218:Condylomata Acuminata / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010409:Penile Diseases / Q000473:pathology / Q000601:surgery; D010412:Penile Neoplasms / Q000473:pathology / Q000601:surgery*; D010413:Penis / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D013521:Urologic Surgical Procedures, Male / Q000379:methods