[Effect of zinc on adrenocorticotropic hormone secretion in the pituitary cell line AtT-20].
The effect of zinc on adrenocorticotropic hormone (ACTH) secretion in the pituitary cell line AtT-20 was studied. Different concentrations of zinc(10(-8) to 1 mmol/L) were added to the medium and ACTH was determined 12 hours later. The findings revealed that zinc within certain concentrations could promote the secretion of ACTH in AtT-20 cells.
Du
K
K
Faculty of Military Health, Fourth Military Medical University, Xi'an 710032, China.
Chen
J
J
D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000818:Animals; D002478:Cells, Cultured; D051379:Mice; D010903:Pituitary Gland, Anterior / Q000378:metabolism* / Q000473:pathology; D010911:Pituitary Neoplasms / Q000378:metabolism* / Q000473:pathology; D015032:Zinc / Q000494:pharmacology*
D000324:Adrenocorticotropic Hormone; D015032:Zinc