title: Cystic hygroma colli as the first echographic sign of the fetal akinesia sequence.
abstract: We report first trimester cystic hygroma colli with subsequent resolution and development of a fetal akinesia deformation sequence. Neuropathological examination of the brain showed intra- and extracellular white matter edema while spinal cord, peripheral nerves and muscles were normal. Hygroma colli as the first echographic sign of subsequent severe fetal akinesia sequence without muscular dystrophy as seen in the Lethal Multiple Pterygium syndrome has not been previously reported.
authors.affiliation: Department of Obstetrics and Gynecology, University of Leuven, Belgium.
authors.forename: I
authors.initials: I
authors.lastname: Witters
authors.forename: P H
authors.initials: PH
authors.lastname: Moerman
authors.forename: F A
authors.initials: FA
authors.lastname: Van Assche
authors.forename: J P
authors.initials: JP
authors.lastname: Fryns
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging* / Q000196:embryology; D001176:Arthrogryposis / Q000000981:diagnostic imaging*; D004487:Edema; D005333:Fetus / Q000002:abnormalities*; D006801:Humans; D008208:Lymphatic System / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000196:embryology; D008210:Lymphocele / Q000000981:diagnostic imaging / Q000196:embryology*; D008297:Male; D016216:Ultrasonography, Prenatal