title: Genetic diversity of Neisseria lactamica strains from epidemiologically defined carriers.
abstract: We assessed the genetic diversity of 26 Neisseria lactamica strains from epidemiologically related sources, i.e., groups of kindergartens and primary schools in three Bavarian towns, by the partial sequencing of the argF, rho, recA, and 16S ribosomal genes. We found a total of 17 genotypes, of which 12 were found only in one strain. The genotypes comprised 5 alleles of the argF gene, 9 of rho, 8 of recA, and 10 of the 16S ribosomal DNA. Sequence analysis by determination of homoplasy ratios and split decomposition analysis revealed abundant recombination within N. lactamica.
authors.affiliation: Institut für Hygiene und Mikrobiologie, Universität Würzburg, Josef-Schneider-Str. 2, 97080 Würzburg, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Alber
authors.forename: M
authors.initials: M
authors.lastname: Oberkötter
authors.forename: S
authors.initials: S
authors.lastname: Suerbaum
authors.forename: H
authors.initials: H
authors.lastname: Claus
authors.forename: M
authors.initials: M
authors.lastname: Frosch
authors.forename: U
authors.initials: U
authors.lastname: Vogel
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D001483:Base Sequence; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D005798:Genes, Bacterial; D020459:Genes, rRNA / Q000235:genetics; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D008589:Meningococcal Infections / Q000453:epidemiology / Q000382:microbiology; D008969:Molecular Sequence Data; D009305:Nasopharynx / Q000382:microbiology*; D009343:Neisseria / Q000145:classification* / Q000235:genetics* / Q000276:immunology; D009345:Neisseria meningitidis / Q000145:classification / Q000235:genetics; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA
chemical_list: D001426:Bacterial Proteins; D012336:RNA, Ribosomal, 16S