Aberrant amplification of A(2A) receptor signaling in striatal cells expressing mutant huntingtin.
Varani
K
K
Dipartimento di Medicina Clinica Sperimentale, Universita' di Ferrara, 44100 Ferrara, Italy.
Rigamonti
D
D
Sipione
S
S
Camurri
A
A
Borea
P A
PA
Cattabeni
F
F
Abbracchio
M P
MP
Cattaneo
E
E
D019830:Adenosine-5'-(N-ethylcarboxamide) / Q000494:pharmacology; D000262:Adenylyl Cyclases / Q000378:metabolism; D002460:Cell Line; D005576:Colforsin / Q000494:pharmacology; D003342:Corpus Striatum / Q000166:cytology* / Q000378:metabolism*; D000242:Cyclic AMP / Q000378:metabolism; D006801:Humans; D000071058:Huntingtin Protein; D006816:Huntington Disease / Q000235:genetics / Q000378:metabolism; D007700:Kinetics; D008954:Models, Biological; D009154:Mutation; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D009687:Nuclear Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D058915:Purinergic P1 Receptor Antagonists; D011869:Radioligand Assay; D043705:Receptor, Adenosine A2A; D018047:Receptors, Purinergic P1 / Q000235:genetics / Q000378:metabolism*; D015290:Second Messenger Systems / Q000502:physiology*; D015398:Signal Transduction
C086055:HTT protein, human; D000071058:Huntingtin Protein; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; D058915:Purinergic P1 Receptor Antagonists; D043705:Receptor, Adenosine A2A; D018047:Receptors, Purinergic P1; D005576:Colforsin; D019830:Adenosine-5'-(N-ethylcarboxamide); D000242:Cyclic AMP; D000262:Adenylyl Cyclases