title: New modified eremophilanes from the roots of Psacalium radulifolium.
abstract: The investigation of the chemical constituents from the roots of Psacalium radulifolium, a member of the matarique complex of medicinal plants, which includes several members of the Asteraceae, resulted in the isolation of four new modified eremophilanes: radulifolin A (4), epi-radulifolin A (5), radulifolin B (6), and radulifolin C (7), together with the known natural substances cacalol, cacalone, epi-cacalone, O-methyl-1,2-dehydrocacalol, adenostin A, decompostin, and neoadenostylone. Antimicrobial evaluation of the extracts and the isolated compounds indicated that cacalol was the major active compound.
authors.affiliation: Instituto de Química de la Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Coyoacán 04510, México, D. F.
authors.forename: M L
authors.initials: ML
authors.lastname: Garduño-Ramírez
authors.forename: A
authors.initials: A
authors.lastname: Trejo
authors.forename: V
authors.initials: V
authors.lastname: Navarro
authors.forename: R
authors.initials: R
authors.lastname: Bye
authors.forename: E
authors.initials: E
authors.lastname: Linares
authors.forename: G
authors.initials: G
authors.lastname: Delgado
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D009281:Naphthalenes / Q000737:chemistry / Q000302:isolation & purification*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; D013057:Spectrum Analysis
chemical_list: D009281:Naphthalenes; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C018286:eremophilane compounds