Phylogenetic study on distribution and chromogranin/secretogranin content of histamine immunoreactive elements in the gut.
The distribution of histamine-immunoreactive (HA-IR) elements and possible coexistence of chromogranin A (CgA), chromogranin B (CgB) and secretogranin II (SgII) were immunohistochemically studied in gut specimens of various vertebrate species. In fish, HA-IR cells were distributed mainly within the gastric and duodenal mucosa, and nerve fibres in the gastric myenteric plexus. Only the gastric HA-IR cells co-stored SgII. In frog specimens, HA-IR endocrine cells and nerve fibres were found in the distal stomach wall, but SgII coexisted only in the nerve fibres. In lizard, HA-IR endocrine cells were widely distributed from the oesophagus to the small intestine, but only those in the stomach co-stored CgA, CgB and SgII. In chick, HA-IR cells were found in the proventriculus and almost all co-stored all three proteins. In rat, HA-IR cells were accumulated in the oxyntic mucosa and all of them constantly immunostained for CgA only.
D'Este
L
L
Institute of Human Anatomy, University La Sapienza, Rome, Italy.
Renda
T
T
D000818:Animals; D001001:Anura / Q000033:anatomy & histology / Q000378:metabolism; D002645:Chickens / Q000033:anatomy & histology / Q000378:metabolism; D002864:Chromogranins / Q000378:metabolism*; D004759:Enterochromaffin Cells / Q000166:cytology* / Q000378:metabolism*; D005399:Fishes / Q000033:anatomy & histology / Q000378:metabolism; D006632:Histamine / Q000378:metabolism*; D008116:Lizards / Q000033:anatomy & histology / Q000378:metabolism; D010802:Phylogeny; D011506:Proteins / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar / Q000033:anatomy & histology / Q000378:metabolism
D002864:Chromogranins; D011506:Proteins; D006632:Histamine