title: Potentially virulent strains and high colony counts of group A beta-haemolytic streptococci in pharyngitis patients having a delayed recovery or a complication.
abstract: T serotyping and M and exotoxin genotyping were performed on strains from 367 streptococcal pharyngitis patients in Dutch general practice. Potentially virulent strains of group A beta-haemolytic streptococci, such as T1M1 and T3M3 subtypes and strains expressing speA and speC, and a high number of colony counts did not occur more frequently in the 166 (45%) more seriously ill patients, defined as those who showed a delayed recovery or a complication.
authors.affiliation: Department of General Practice, University Medical Center, Utrecht, The Netherlands. szwart@knmg.nl
authors.forename: S
authors.initials: S
authors.lastname: Zwart
authors.forename: G J
authors.initials: GJ
authors.lastname: Ruijs
authors.forename: A P
authors.initials: AP
authors.lastname: Sachs
authors.forename: J F
authors.initials: JF
authors.lastname: Schellekens
authors.forename: R A
authors.initials: RA
authors.lastname: de Melker
mesh_terms: D000328:Adult; D001426:Bacterial Proteins / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D015169:Colony Count, Microbial; D005098:Exotoxins; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism; D010612:Pharyngitis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D013291:Streptococcus / Q000235:genetics / Q000276:immunology / Q000378:metabolism / Q000472:pathogenicity*; D014774:Virulence
chemical_list: D001426:Bacterial Proteins; D005098:Exotoxins; D008565:Membrane Proteins; C117980:SpeA protein, Streptococcus pyogenes