title: Increase in number and size of kidney concretions as a result of PCP exposure in the freshwater snail Planorbarius corneus (Gastropoda, Pulmonata).
abstract: Molluscan kidneys are able to excrete solids in the urine in the form of concretions. It is thought that increased formation of these concretions occur under pollutant, environmentally or reproductive induced stress. This study examined the formation of concretions in the kidney of the freshwater snail Planorbarius corneus L. experimentally exposed to pentachlorophenol (PCP). Light microscopic histopathological analysis of the PCP-exposed P. corneus revealed significantly enhanced production of the kidney concretions when compared to the kidneys of control individuals. Measurements of the number of kidney concretions, the apparent area of the concretions, and the epithelial area filled with concretions indicated an increase in the number and size of concretions in all treated snails. Lipofuscin content of excretory cell concretions was detected.
authors.affiliation: Department of Zoology, Faculty of Science, University of Zagreb, Croatia. gklobuca@public.srce.hr
authors.forename: G I
authors.initials: GI
authors.lastname: Klobucar
authors.forename: J
authors.initials: J
authors.lastname: Lajtner
authors.forename: R
authors.initials: R
authors.lastname: Erben
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D010622:Phencyclidine / Q000008:administration & dosage / Q000633:toxicity*; D012908:Snails / Q000187:drug effects*
chemical_list: D010622:Phencyclidine