title: The association of testosterone with nicotine use in young adult females.
abstract: This pilot laboratory study examined the relationship of testosterone levels, carbon monoxide (CO) levels, current and adolescent nicotine use, and histories of pubertal onset in 30 young adult female smokers. These females had completed questionnaires regarding nicotine use in the 7th through 10th grades, and again at age 21 as part of a cohort study of drug use. In addition, history of pubertal onset was obtained at age 21, as were testosterone and CO levels. Testosterone levels were positively correlated with cigarette use in the last 30 days (P< or =.01), CO levels (P< or =.05), cigarette use reported in the 7th and 10th grades (P< or =.05), and negatively correlated with age of pubertal onset (P< or =.001). The relationship of testosterone to nicotine will be discussed.
authors.affiliation: Department of Psychiatry, University of Kentucky College of Medicine, Lexington 40509-1810, USA. cmartin@pop.uky.edu
authors.forename: C A
authors.initials: CA
authors.lastname: Martin
authors.forename: T K
authors.initials: TK
authors.lastname: Logan
authors.forename: C
authors.initials: C
authors.lastname: Portis
authors.forename: C G
authors.initials: CG
authors.lastname: Leukefeld
authors.forename: D
authors.initials: D
authors.lastname: Lynam
authors.forename: M
authors.initials: M
authors.lastname: Staton
authors.forename: B
authors.initials: B
authors.lastname: Brogli
authors.forename: K
authors.initials: K
authors.lastname: Flory
authors.forename: R R
authors.initials: RR
authors.lastname: Clayton
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior / Q000523:psychology*; D002248:Carbon Monoxide / Q000378:metabolism; D005260:Female; D006801:Humans; D010865:Pilot Projects; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D013739:Testosterone / Q000378:metabolism*; D014029:Tobacco Use Disorder / Q000378:metabolism*
chemical_list: D013739:Testosterone; D002248:Carbon Monoxide