title: [Prevalence of chronic hidden infections in a cohort of patients in substitutive treatment with methadone].
abstract: BACKGROUND
  To analyse prevalence of hidden hepatitis B infection (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and tuberculosis infection in drug users (DU) in a maintenance programme with methadone (MPM).
  
  
  METHODS
  189 DU were tested for HBV, HCV, HIV and tuberculin test. Drug addition history and route of administration were evaluated.
  
  
  RESULTS
  Prevalence of HIV, HCV, and tuberculous infection was 29.2%, 75.9% and 59.3% respectively. Intravenous route, early use of heroin and delay to enter in MPM were significatively associated with HIV and HCV infections.
  
  
  CONCLUSIONS
  There is a high prevalence of tuberculous and HCV infections in DU. Early access to MPM could decrease prevalence of those infections.
authors.affiliation: Unidades de Enfermedades Infecciosas. Hospital General Universitario de Alicante. portilla_joa@gva.es
authors.forename: J
authors.initials: J
authors.lastname: Portilla
authors.forename: J
authors.initials: J
authors.lastname: Esteban
authors.forename: R
authors.initials: R
authors.lastname: Llinares
authors.forename: J
authors.initials: J
authors.lastname: Belda
authors.forename: J
authors.initials: J
authors.lastname: Sánchez-Payá
authors.forename: M
authors.initials: M
authors.lastname: Isabel Manso
authors.forename: G
authors.initials: G
authors.lastname: de Estudio Protocolo-INH
mesh_terms: D000328:Adult; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology*; D019694:Hepatitis B, Chronic / Q000150:complications / Q000453:epidemiology*; D019698:Hepatitis C, Chronic / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D009294:Narcotics / Q000627:therapeutic use*; D015995:Prevalence; D019966:Substance-Related Disorders / Q000150:complications / Q000534:rehabilitation*; D014376:Tuberculosis / Q000150:complications / Q000453:epidemiology*
chemical_list: D009294:Narcotics; D008691:Methadone