title: CT colonography: single- versus multi-detector row imaging.
abstract: OBJECTIVE
  To compare respiratory artifacts, colonic distention, and polyp detection at computed tomographic (CT) colonography by using single- and multi-detector row helical CT systems.
  
  
  METHODS
  A total of 237 consecutive patients received subcutaneously administered glucagon and underwent prone and supine CT colonography with single-detector row CT (n = 77) and multi-detector row CT (n = 160), followed by colonoscopy. Examination results were graded for colonic distention, respiratory artifacts, and polyp depiction by two radiologists working independently.
  
  
  RESULTS
  Suboptimal colonic distention was significantly more common with single-detector row CT and was present in at least one segment in 52% (40 of 77 patients) of examinations versus only 19% (30 of 160 patients) with multi-detector row CT (P <.001). Mild respiratory artifacts were present in 61% (47 of 77 patients) of single-detector row CT examinations versus only 16% (26 of 160 patients) of multi-detector row CT examinations (P <.001). Depiction of polyps larger than 10 mm was 89% (eight of nine polyps) for single-detector row CT and 80% (eight of 10 polyps) for multi-detector row CT (P >.05).
  
  
  CONCLUSIONS
  CT colonography performed with multi-detector row CT significantly improved the demonstration of colonic distention and depicted fewer respiratory artifacts compared with single-detector row CT. No significant differences in the depiction of polyps larger than 10 mm were demonstrated between single- and multi-detector row CT for a small number of polyps. Studies with a larger prevalence of clinically important polyps are needed for further evaluation of differences in polyp detection.
authors.affiliation: Department of Diagnostic Radiology, Mallinckrodt Institute of Radiology, 510 S Kingshighway Blvd, St Louis, MO 63110, USA. haraa2@yahoo.com
authors.forename: A K
authors.initials: AK
authors.lastname: Hara
authors.forename: C D
authors.initials: CD
authors.lastname: Johnson
authors.forename: R L
authors.initials: RL
authors.lastname: MacCarty
authors.forename: T J
authors.initials: TJ
authors.lastname: Welch
authors.forename: C H
authors.initials: CH
authors.lastname: McCollough
authors.forename: W S
authors.initials: WS
authors.lastname: Harmsen
mesh_terms: D000328:Adult; D000368:Aged; D016477:Artifacts; D003106:Colon / Q000000981:diagnostic imaging*; D003111:Colonic Polyps / Q000175:diagnosis / Q000000981:diagnostic imaging*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D012119:Respiration; D012680:Sensitivity and Specificity; D015898:Tomography Scanners, X-Ray Computed; D014057:Tomography, X-Ray Computed / Q000379:methods*