title: [Challenge of evidence-based medicine: sense and non-sense of diagnostic tests in gynecology].
abstract: Evidence-based medicine is the synthesis of internal evidence (experience) and best external evidence (literature) aiming to solve a particular clinical problem. This paper gives an overview on different tools to appraise rationales and results of diagnostic tests such as CA-125 monitoring in patients with ovarian cancer.
authors.affiliation: Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Charité Campus Virchow-Klinikum der Humboldt-Universität zu Berlin. jalid.sehouli@charite.de
authors.forename: J
authors.initials: J
authors.lastname: Sehouli
authors.forename: D
authors.initials: D
authors.lastname: Stengel
authors.forename: J
authors.initials: J
authors.lastname: Hindenburg
authors.forename: O
authors.initials: O
authors.lastname: Camara
authors.forename: F
authors.initials: F
authors.lastname: Porzsolt
authors.forename: W
authors.initials: W
authors.lastname: Lichtenegger
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood*; D018394:CA-125 Antigen / Q000097:blood*; D003362:Cost-Benefit Analysis; D019317:Evidence-Based Medicine / Q000379:methods*; D005260:Female; D005858:Germany; D006176:Gynecology / Q000191:economics / Q000592:standards*; D006801:Humans; D008403:Mass Screening / Q000191:economics / Q000379:methods / Q000592:standards*; D016017:Odds Ratio; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000191:economics / Q000276:immunology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D014408:Biomarkers, Tumor; D018394:CA-125 Antigen