Bioactive glass granules for regeneration of human periodontal defects.
OBJECTIVE
A comparative study which evaluated the effectiveness of bioactive glass granules of uniform size (300-335 microns) for the regenerative treatment of interproximal intrabony periodontal defects was conducted.


METHODS
Twelve pairs of advanced periodontal lesions in 12 patients (6 males and 6 females) were treated in a split-mouth design with open flap débridement in the control sites and open flap débridement with bioactive glass particles placed in the test sites.


RESULTS
At 6 months post-treatment, both treatment modalities demonstrated a gain in clinical attachment level (CAL), with the test sites having a significantly (p < .01) greater gain in CAL than the control sites. Reentry procedures were performed to assess the amount of hard tissue fill. The test sites demonstrated significantly (p < .001) more gain in hard tissue fill than the controls.
Rosenberg
E S
ES
New York University College of Dentistry, New York, New York, USA. erosen9468@aol.com
Fox
G K
GK
Cohen
C
C
D000328:Adult; D016301:Alveolar Bone Loss / Q000601:surgery*; D001672:Biocompatible Materials; D001861:Bone Regeneration; D018786:Bone Substitutes; D005260:Female; D005898:Glass; D006801:Humans; D008297:Male; D010316:Particle Size; D017622:Periodontal Attachment Loss / Q000601:surgery
D001672:Biocompatible Materials; C073544:Biogran; D018786:Bone Substitutes