title: Structure of the macrocycle thiostrepton solved using the anomalous dispersion contribution of sulfur.
abstract: The structure of a tetragonal crystal form of thiostrepton has been solved using the anomalous dispersive effects of five S atoms from high-redundancy data collected to 1.33 A resolution at the Cu Kalpha wavelength. Data measured to 1.02 A resolution with a synchrotron source were used for refinement. Details of the molecular structure, intramolecular and intermolecular interactions are given.
authors.affiliation: The Wellcome Trust Biocentre, University of Dundee, Dundee DD1 5EH, Scotland, UK.
authors.forename: C S
authors.initials: CS
authors.lastname: Bond
authors.forename: M P
authors.initials: MP
authors.lastname: Shaw
authors.forename: M S
authors.initials: MS
authors.lastname: Alphey
authors.forename: W N
authors.initials: WN
authors.lastname: Hunter
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry*; D003460:Crystallization; D008958:Models, Molecular; D011487:Protein Conformation; D013455:Sulfur / Q000737:chemistry*; D013883:Thiostrepton / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D013455:Sulfur; D013883:Thiostrepton