Effect of vaccination in the field with the Theileria annulata (Hisar) cell culture vaccine on young calves born during the winter season.
The responses were monitored of young crossbred calves vaccinated against tropical theileriosis during the winter against a field tick challenge in the disease season. Thirty-eight calves below 2 months of age, born after the end of the disease season, were selected at an organized farm. Twenty-five animals were vaccinated with Theileria annulata (Hisar) cell culture vaccine (developed at CCS HAU Hisar laboratory) after the end of the disease season and 13 calves were kept as non-vaccinated controls. These calves were observed for their susceptibility to theileriosis in the new disease season. There was an increase in antibody titre in 18 of the 25 vaccinated animals one month after vaccination. The antibody titre then declined gradually, but remained higher than those of the non-vaccinated animals at month 0. No fever or other clinical signs of tropical theileriosis were observed in any of the vaccinated animals. Nine out of 25 (36%) vaccinated calves showed occasional piroplasms (<0.5%) in blood smears. All the vaccinated animals withstood the field tick challenge. On the other hand, 9 of the 13 (69%) unvaccinated calves exhibited occasional piroplasms, and included three clinical cases of tropical theileriosis. These observations suggest that young crossbred calves vaccinated with the T. annulata (Hisar) cell culture vaccine at the end of the disease season were relatively resistant during the next disease season.
Khatri
N
N
Department of Veterinary Medicine, CCS Haryana Agricultural University, Hisar, India.
Nichani
A K
AK
Sharma
R D
RD
Khatri
M
M
Malhotra
D V
DV
D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D001831:Body Temperature; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology* / Q000469:parasitology / Q000517:prevention & control; D003433:Crosses, Genetic; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D006400:Hematocrit / Q000662:veterinary; D006454:Hemoglobins / Q000032:analysis; D007958:Leukocyte Count / Q000662:veterinary; D008137:Longitudinal Studies; D018512:Parasitemia / Q000662:veterinary; D016052:Protozoan Vaccines / Q000276:immunology / Q000627:therapeutic use; D012621:Seasons; D016796:Theileria annulata / Q000254:growth & development / Q000276:immunology*; D013801:Theileriasis / Q000276:immunology* / Q000469:parasitology / Q000517:prevention & control; D013984:Tick Infestations / Q000662:veterinary; D013987:Ticks / Q000469:parasitology; D014611:Vaccination / Q000662:veterinary*
D000913:Antibodies, Protozoan; D006454:Hemoglobins; D016052:Protozoan Vaccines