title: Use of fluoridated dentifrice and glucose retention at the approximal areas of anterior teeth.
abstract: The present study was undertaken to learn to what extent the use of dentifrice with fluoride affected glucose retention after glucose rinsing. Fifty-eight subjects consisting of forty male adults and eighteen female adults whose average age was 21.9 years were divided at random into two groups; one group used fluoridated dentifrice and the other group used nonfluoridated dentifrice. Subjects rinsed their mouths for fifteen seconds with 20 mL of 0.5 M glucose solution. Samples of saliva were taken from the approximal areas between the right and left central incisors of the maxilla and mandible by inserting the tip portion of a paper point three-minutes after the glucose rinsing, sample of saliva were taken from the neighboring approximal areas of the left central and left lateral incisors. Glucose content of the paper points was determined using the enzyme membrane method. Determinations were made before and at the end of the first, third, and fifth month over a five-month period. Fluoride concentrations in the resting saliva were also determined in different months during this period. At three-minutes and six-minutes, glucose retention in the group using fluoridated dentifrice was found to decrease slightly throughout the experiment; while glucose retention in the group on nonfluoridated dentifrice leveled off or increased in the fifth month. Fluoride concentration in the resting saliva increased during the experiment in the group using fluoridated dentifrice; while fluoride concentration in the group using nonfluoridated dentifrice did not change. It was concluded that the regular use of fluoridated dentifrice made glucose retention slightly lower and fluoride level in whole saliva higher.
authors.affiliation: Department of Preventive Dentistry and Dental Public Health, School of Dentistry, Aichi-Gakuin University, 1-100 Kusumoto-cho, Chikusa-ku, Nagoya 464-8650, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Isogai
authors.forename: H
authors.initials: H
authors.lastname: Nakagaki
authors.forename: M
authors.initials: M
authors.lastname: Hanaki
authors.forename: S
authors.initials: S
authors.lastname: Tsuboi
authors.forename: I
authors.initials: I
authors.lastname: Morita
authors.forename: C
authors.initials: C
authors.lastname: Osaka
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002327:Cariostatic Agents / Q000008:administration & dosage / Q000032:analysis / Q000627:therapeutic use*; D003802:Dentifrices / Q000627:therapeutic use*; D005260:Female; D005459:Fluorides / Q000008:administration & dosage / Q000032:analysis / Q000627:therapeutic use*; D005500:Follow-Up Studies; D005947:Glucose / Q000008:administration & dosage / Q000032:analysis / Q000493:pharmacokinetics*; D006801:Humans; D007180:Incisor / Q000033:anatomy & histology / Q000378:metabolism*; D008297:Male; D008334:Mandible; D008437:Maxilla; D009067:Mouthwashes; D012463:Saliva / Q000737:chemistry / Q000378:metabolism; D013223:Statistics as Topic; D013997:Time Factors
chemical_list: D002327:Cariostatic Agents; D003802:Dentifrices; D009067:Mouthwashes; D005947:Glucose; D005459:Fluorides