Uterine artery embolization in an undiagnosed uterine sarcoma.
BACKGROUND
Uterine sarcomas are rare malignancies that resemble benign uterine leiomyomata. Uterine artery embolization is offered increasingly for treatment of uterine leiomyomata, which might lead to embolization of undiagnosed uterine sarcoma.


METHODS
A 52-year-old woman, gravida 7, para 6, with perimenopausal menometrorrhagia was diagnosed with uterine leiomyomata after physical examination and transvaginal ultrasound. An endometrial biopsy was negative for malignancy. After medical treatment was unsuccessful, she had uterine artery embolization. She then passed a piece of tissue from her vagina, the pathology report of which was necrotic high-grade sarcoma. During surgery we confirmed that the tumor was confined to the uterus.


CONCLUSIONS
Uterine sarcoma cannot be diagnosed except by pathologic examination of a resected specimen. Women considering uterine artery embolization for treatment of apparent leiomyomata should be counseled on the risk of decreased survival by delaying diagnosis and treatment of uterine sarcoma.
Al-Badr
A
A
Division Gynecologic Oncology, Department of Ob/Gyn, University of Ottawa, Ottawa, Ontario, Canada. ahmed@albadr.com
Faught
W
W
D003937:Diagnosis, Differential; D004621:Embolization, Therapeutic; D005260:Female; D015658:HIV Infections / Q000150:complications; D006801:Humans; D018231:Leiomyomatosis / Q000150:complications / Q000628:therapy*; D008875:Middle Aged; D012509:Sarcoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014594:Uterine Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery