title: [The advances of research for cardiac contractile proteins structure and function].
abstract: Cardiac contractile proteins are the material basis of cardiac contractility. This paper introduces the Structures of two major cardiac contractile proteins: myosin and actin, especially the details of the two proteins' structure relevant to their function. At the same time, it describes the myosin and actin proteins' changes in normal and abnormal hearts so as to enrich our mind with knowledge of cardiac hypertrophy and heart failure at the molecular level.
authors.affiliation: Biomedical Engineering Research Unit, West China University of Medical Sciences, Chengdu 610041.
authors.forename: L
authors.initials: L
authors.lastname: Wei
authors.forename: L
authors.initials: L
authors.lastname: Wang
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
mesh_terms: D000199:Actins / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D000818:Animals; D002303:Cardiac Output, Low / Q000235:genetics / Q000378:metabolism; D006332:Cardiomegaly / Q000235:genetics / Q000378:metabolism; D003285:Contractile Proteins / Q000737:chemistry* / Q000502:physiology*; D006333:Heart Failure / Q000378:metabolism; D006801:Humans; D009218:Myosins / Q000737:chemistry / Q000235:genetics / Q000502:physiology
chemical_list: D000199:Actins; D003285:Contractile Proteins; D009218:Myosins