An unusual case of fatal pulmonary allograft rejection.
This case report describes an atypical form of acute pulmonary allograft rejection that was refractory to conventional therapy. The rejection manifested primarily as interstitial lymphocytic infiltrates with little perivascular involvement. Despite aggressive therapy the patient died within 7 months of transplant. The timely recognition and treatment of unusual forms of allograft rejection is vital in the management of pulmonary transplant patients.
Mogayzel
P J
PJ
Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins Medical Institutions, 600 North Wolfe Street, Baltimore, MD 21287-2533, USA. mogayzel@mail.jhmi.edu
Wise
B V
BV
Yang
S C
SC
Zachary
A A
AA
Colombani
P M
PM
D000293:Adolescent; D017809:Fatal Outcome; D005260:Female; D006084:Graft Rejection / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D016040:Lung Transplantation; D017893:Photopheresis; D013601:T-Lymphocytes / Q000473:pathology; D014184:Transplantation, Homologous