[Prevalence of chronic hidden infections in a cohort of patients in substitutive treatment with methadone].
BACKGROUND
To analyse prevalence of hidden hepatitis B infection (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and tuberculosis infection in drug users (DU) in a maintenance programme with methadone (MPM).


METHODS
189 DU were tested for HBV, HCV, HIV and tuberculin test. Drug addition history and route of administration were evaluated.


RESULTS
Prevalence of HIV, HCV, and tuberculous infection was 29.2%, 75.9% and 59.3% respectively. Intravenous route, early use of heroin and delay to enter in MPM were significatively associated with HIV and HCV infections.


CONCLUSIONS
There is a high prevalence of tuberculous and HCV infections in DU. Early access to MPM could decrease prevalence of those infections.
Portilla
J
J
Unidades de Enfermedades Infecciosas. Hospital General Universitario de Alicante. portilla_joa@gva.es
Esteban
J
J
Llinares
R
R
Belda
J
J
Sánchez-Payá
J
J
Isabel Manso
M
M
de Estudio Protocolo-INH
G
G
D000328:Adult; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology*; D019694:Hepatitis B, Chronic / Q000150:complications / Q000453:epidemiology*; D019698:Hepatitis C, Chronic / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D009294:Narcotics / Q000627:therapeutic use*; D015995:Prevalence; D019966:Substance-Related Disorders / Q000150:complications / Q000534:rehabilitation*; D014376:Tuberculosis / Q000150:complications / Q000453:epidemiology*
D009294:Narcotics; D008691:Methadone