title: Survey of residual tetracyclines in kidneys of diseased animals in Aichi Prefecture, Japan (1985-1997).
abstract: A survey was conducted to determine the incidence of tetracycline antibiotic (TCAs) residues in the kidneys of slaughtered animals that did not pass inspection for human consumption by the Japanese Food Sanitation Law and the Meat Inspection Law at the slaughterhouses in Aichi Prefecture, Japan, from April 1985 to March 1998. The kidneys were analyzed by the AOAC Official Method 995.09. Among 424 animals (147 cattle and 277 pigs), 131 (30.9%) were contaminated with TCAs, including 69 (16.3%) with chlortetracycline (CTC), 61 (14.4%) with oxytetracycline (OTC), 3 (0.7%) with tetracycline (TC), and 1 (0.2%) with doxycycline (DC). One sample (cattle kidney) was contaminated with both OTC and DC. The frequencies of OTC and TC residues were significantly higher (p < 0.05) in cattle than in pigs, whereas, the frequency of CTC was significantly higher (p < 0.01) in pigs. Pig kidney samples collected in 1991-1997 had significantly higher incidences of TCAs and CTC (p < 0.01) residues than those in 1985-1986.
authors.affiliation: Aichi Prefectural Institute of Public Health, Nagoya, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Oka
authors.forename: Y
authors.initials: Y
authors.lastname: Ito
authors.forename: Y
authors.initials: Y
authors.lastname: Ikai
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: K
authors.initials: K
authors.lastname: Kato
authors.forename: I
authors.initials: I
authors.lastname: Yamamoto
authors.forename: M
authors.initials: M
authors.lastname: Shimizu
authors.forename: N
authors.initials: N
authors.lastname: Kawamura
authors.forename: Y
authors.initials: Y
authors.lastname: Miyazaki
authors.forename: T
authors.initials: T
authors.lastname: Nojiri
authors.forename: M
authors.initials: M
authors.lastname: Okumura
authors.forename: S
authors.initials: S
authors.lastname: Ohmi
authors.forename: T
authors.initials: T
authors.lastname: Sato
authors.forename: G
authors.initials: G
authors.lastname: Mori
mesh_terms: D000820:Animal Diseases / Q000378:metabolism*; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000378:metabolism; D004350:Drug Residues / Q000032:analysis*; D007202:Indicators and Reagents; D007564:Japan; D007668:Kidney / Q000737:chemistry*; D013552:Swine; D013553:Swine Diseases / Q000378:metabolism; D013752:Tetracycline / Q000032:analysis*
chemical_list: D007202:Indicators and Reagents; D013752:Tetracycline