title: Pregnancy with cytochrome oxidase-deficient mitochondrial myopathy.
abstract: BACKGROUND
  Cytochrome oxidase-deficient mitochondrial myopathies represent a heterogeneous group of muscle disorders. Physical stress can cause life-threatening risks related to rhabdomyolysis or respiratory compromise.
  
  
  METHODS
  A 21-year-old primigravida with cytochrome C oxidase-deficient mitochondrial myopathy who presented for obstetric care at 8 weeks' gestation complained of muscle fatigue and spasm after exertion. The increased metabolic demands of pregnancy led to worsening pain, muscle fatigue, and ultimately complete immobility.
  
  
  CONCLUSIONS
  Cytochrome oxidase-deficient mitochondrial myopathies are rare but serious complications of pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Memorial University of Newfoundland, 300 Prince Phillip Drive, St. John's, Newfoundland A1B 3V6, Canada.
authors.forename: P S
authors.initials: PS
authors.lastname: Soccio
authors.forename: W P
authors.initials: WP
authors.lastname: Phillips
authors.forename: P
authors.initials: P
authors.lastname: Bonisteel
authors.forename: K A
authors.initials: KA
authors.lastname: Bennett
mesh_terms: D000328:Adult; D030401:Cytochrome-c Oxidase Deficiency; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D017240:Mitochondrial Myopathies / Q000628:therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011256:Pregnancy Outcome; D011295:Prenatal Care