title: Xenopus Eya1 demarcates all neurogenic placodes as well as migrating hypaxial muscle precursors.
abstract: We cloned two isoforms of the Xenopus Eya1 orthologue. They show identical patterns of expression that closely resemble the previously described expression of XSix1, but partly differ from the expression of Eya1 in other vertebrates. XEya1 is expressed in the somites and hypaxial muscle precursors, but not in the pronephros. Moreover, all ectodermal placodes except the lens placode strongly express XEya1. At neural plate stages, ectodermal XEya1 expression starts in two domains, the anterior neural folds and a domain lateral to the neural folds. At tailbud stages, XEya1 expression continues in the adenohypophysis, all neurogenic placodes and placodally-derived structures including cranial ganglia, the otic vesicle and lateral line primordia.
authors.affiliation: Department of Biochemistry, University of Ulm, Albert-Einstein-Allee 11, D-89081 Ulm, Germany. robert.david@medizin.uni-ulm. de
authors.forename: R
authors.initials: R
authors.lastname: David
authors.forename: K
authors.initials: K
authors.lastname: Ahrens
authors.forename: D
authors.initials: D
authors.lastname: Wedlich
authors.forename: G
authors.initials: G
authors.lastname: Schlosser
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002465:Cell Movement; D003001:Cloning, Molecular; D004475:Ectoderm / Q000378:metabolism; D017403:In Situ Hybridization; D047908:Intracellular Signaling Peptides and Proteins; D008969:Molecular Sequence Data; D009474:Neurons / Q000378:metabolism; D009687:Nuclear Proteins; D020033:Protein Isoforms; D017027:Protein Tyrosine Phosphatases; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017386:Sequence Homology, Amino Acid; D013997:Time Factors; D015534:Trans-Activators / Q000096:biosynthesis*; D014981:Xenopus / Q000196:embryology*; D029867:Xenopus Proteins
chemical_list: D047908:Intracellular Signaling Peptides and Proteins; D009687:Nuclear Proteins; D020033:Protein Isoforms; D015534:Trans-Activators; D029867:Xenopus Proteins; C501157:Eya1 protein, Xenopus; D017027:Protein Tyrosine Phosphatases