Exercise and atherogenesis.
Atherogenesis involves the activation of endothelial cells and the egress of atherogenic T lymphocytes and monocytes into the intima. Exercise training contributes to the arrest and even reversal of atherosclerosis by modifying risk factors and by inducing an atheroprotective phenotype in endothelial cells and T cells.
Smith
J K
JK
Division of Immunology, Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee, TN 37614, USA. smithj@etsu.edu
D000818:Animals; D017951:Antigen Presentation; D001161:Arteriosclerosis / Q000276:immunology / Q000503:physiopathology*; D016207:Cytokines / Q000502:physiology; D004730:Endothelium, Vascular / Q000503:physiopathology*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D007249:Inflammation / Q000503:physiopathology; D007371:Interferon-gamma / Q000502:physiology; D007963:Leukocytes, Mononuclear / Q000502:physiology; D023421:Models, Animal; D010587:Phagocytosis; D013601:T-Lymphocytes / Q000502:physiology; D014409:Tumor Necrosis Factor-alpha / Q000502:physiology
D016207:Cytokines; D014409:Tumor Necrosis Factor-alpha; D007371:Interferon-gamma