The coexistence of systemic lupus erythematosus and multiple sclerosis in a mother and daughter.
The occurrence of both multiple sclerosis (MS) and systemic lupus erythematosus (SLE) has previously been described in several members within the same family and in twins of successive generations, but the finding of both diseases in one patient is a great rarity. We here report on a rare coexistence of MS and SLE both in mother and daughter. Both patients fulfill the diagnostic criteria of primary-progressive subtype of MS as well as SLE. The finding constitutes supporting evidence of a common genetic background for these two autoimmune disorders.
Hietaharju
A
A
Department of Neurology and Rehabilitation, Tampere University Hospital, Finland. hietahar@koti.tpo.fi
Peltola
J
J
Seppä
J
J
Luukkainen
R
R
Dastidar
P
P
D000328:Adult; D005192:Family Health; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000235:genetics; D009103:Multiple Sclerosis / Q000150:complications* / Q000235:genetics; D009679:Nuclear Family