[Challenge of evidence-based medicine: sense and non-sense of diagnostic tests in gynecology].
Evidence-based medicine is the synthesis of internal evidence (experience) and best external evidence (literature) aiming to solve a particular clinical problem. This paper gives an overview on different tools to appraise rationales and results of diagnostic tests such as CA-125 monitoring in patients with ovarian cancer.
Sehouli
J
J
Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Charité Campus Virchow-Klinikum der Humboldt-Universität zu Berlin. jalid.sehouli@charite.de
Stengel
D
D
Hindenburg
J
J
Camara
O
O
Porzsolt
F
F
Lichtenegger
W
W
D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood*; D018394:CA-125 Antigen / Q000097:blood*; D003362:Cost-Benefit Analysis; D019317:Evidence-Based Medicine / Q000379:methods*; D005260:Female; D005858:Germany; D006176:Gynecology / Q000191:economics / Q000592:standards*; D006801:Humans; D008403:Mass Screening / Q000191:economics / Q000379:methods / Q000592:standards*; D016017:Odds Ratio; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000191:economics / Q000276:immunology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D014408:Biomarkers, Tumor; D018394:CA-125 Antigen