[Bullous form of X-linked congenital retinoschisis in infants].
Clinical manifestations and course of bullous X-linked congenital retinoschisis were studied in 10 infants aged 6-18 months. Visual function was evaluated by registration of electroretinogram and visual evoked potentials. The patients were followed up for 7.65 +/- 2.51 years. Giant retinal cysts were observed in 40% patients with X-linked retinoschisis aged under 3 years. Collapse (spontaneous or after laser coagulation of the retina) of retinal cysts with formation of demarcation pigmented lines was observed in 85% children. Twenty percent patients developed hemophthalmia which was completely resorbed within 4-12 months. At the age of 6-12 years visual acuity was 0.36 +/- 0.23. The prognosis of the condition is favorable, and therefore surgical treatment or laser coagulation are not recommended in infants with bullous retinoschisis, on condition that no negative changes in the disease course are observed.
Mosin
I M
IM
Moshetova
L K
LK
Mishustin
V V
VV
Letneva
I A
IA
D000367:Age Factors; D002648:Child; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005500:Follow-Up Studies; D008040:Genetic Linkage; D006801:Humans; D007223:Infant; D008297:Male; D011379:Prognosis; D012167:Retinal Perforations / Q000151:congenital* / Q000175:diagnosis / Q000235:genetics*; D013997:Time Factors; D014792:Visual Acuity; D014960:X Chromosome