title: [A clinicopathological analysis of keratoacanthoma in eye].
abstract: OBJECTIVE
  To discuss clinic and histopathologic features of keratoacanthoma. The diagnosis and differential diagnosis were discussed.
  
  
  METHODS
  The authors analyze clinical characteristics of keratoacanthoma which is testified by hisopathology. Clinically, the tumors developed rapidly. They appeared as a dome or nodule with a central keratin filled crater and elevated rolled margins.
  
  
  RESULTS
  Histologically, they had a cup-differentiated squamous opithalium surrounding a central mass of keratin. The base was rather uniform. The lesions may extend into underlying stroma even orbicularis muscle.
  
  
  CONCLUSIONS
  Keratoacanthoma is a specialized variant of pseudocarcinomatous hyperplasia. It has clinic and histopathologic characteristics and differs from other tumors.
authors.affiliation: Zongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Kang
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: Z
authors.initials: Z
authors.lastname: Wu
mesh_terms: D000328:Adult; D000368:Aged; D003229:Conjunctival Diseases / Q000473:pathology*; D003937:Diagnosis, Differential; D005141:Eyelid Diseases / Q000473:pathology*; D005260:Female; D006801:Humans; D007636:Keratoacanthoma / Q000473:pathology*; D008297:Male; D008875:Middle Aged