title: Itraconazole for treatment of sporotrichosis in a dog residing on a Christmas tree farm.
abstract: Sporotrichosis was diagnosed in a 2-year-old male Golden Retriever that was allowed to roam free on the owner's Christmas tree farm in Minnesota. Clinical signs had been evident for 1 month and included swelling of the claw bed of the third digit on the left forelimb and a fluctuant nodular lesion in the area of the left carpus. Few organisms were seen in affected tissues, and diagnosis was confirmed on the basis of results of fungal culture. The condition responded to treatment with itraconazole. Previous reports of sporotrichosis in dogs have described lesions that were distributed predominantly on the head, ears, and trunk. A history of exposure to environments that favor survival of the organism may be an important consideration when evaluating animals suspected to have sporotrichosis. To the authors' knowledge, use of itraconazole to treat a dog with sporotrichosis has not been reported previously.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul 55108, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Sykes
authors.forename: S M
authors.initials: SM
authors.lastname: Torres
authors.forename: P J
authors.initials: PJ
authors.lastname: Armstrong
authors.forename: C J
authors.initials: CJ
authors.lastname: Lindeman
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use*; D004283:Dog Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D004285:Dogs; D005528:Foot / Q000382:microbiology / Q000473:pathology; D017964:Itraconazole / Q000627:therapeutic use*; D008297:Male; D013175:Sporothrix / Q000302:isolation & purification; D013174:Sporotrichosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole