In-vivo quantitative hydrolipidic map of perirenal adipose tissue by chemical shift imaging at 4.7 Tesla.
OBJECTIVE
In this work, chemical shift magnetic resonance imaging is used for in vivo quantitative evaluation of fat and water content in the perirenal white adipose tissue.


METHODS
Experiments were carried out on female Sprague-Dawley rats with a 4.7 T magnet. Fat and water fractions were computed pixel-by-pixel from the chemical shift selective images with an algorithm of reconstruction that allowed parametric maps (called hydrolipidic maps) to be produced with a pixel size of 625 x 625 microm.


RESULTS
Our findings indicate that, in the perirenal adipose tissue, the water content ranges between 15% and 20%, with slight differences between the ventral and dorsal portions, and between the left and right deposits. The mesenteric adipose tissue, observed for comparison, has a mean water content of 30%.


CONCLUSIONS
The present work demonstrates that methods based on magnetic resonance imaging can be useful tools for non-invasive in vivo quantitative mapping of the hydrolipidic content of adipose tissues.
Lunati
E
E
Magnetic Resonance Laboratory, Institute of Human Anatomy and Histology, University of Verona, Verona, Italy.
Marzola
P
P
Nicolato
E
E
Sbarbati
A
A
D000273:Adipose Tissue / Q000033:anatomy & histology* / Q000737:chemistry; D000465:Algorithms; D000818:Animals; D001834:Body Water / Q000737:chemistry*; D005260:Female; D007668:Kidney; D008055:Lipids / Q000032:analysis*; D008279:Magnetic Resonance Imaging; D019047:Phantoms, Imaging; D051381:Rats; D017207:Rats, Sprague-Dawley
D008055:Lipids