title: Niflumic acid and cutaneous reactions in children.
abstract: In a case control study of adverse drug reactions in children, the odds ratio of developing a serious mucocutaneous event among users of niflumic acid, adjusted for concomitant use of all other drugs, was 4.9 (95% CI 1.9 to 12.8). Given the availability of safer analgesics and antipyretics, there is no indication, in our opinion, that requires the prescription of substances which bear an increased risk.
authors.affiliation: Department of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy. fmenniti@iss.it
authors.forename: F
authors.initials: F
authors.lastname: Menniti-Ippolito
authors.forename: L
authors.initials: L
authors.lastname: Sagliocca
authors.forename: R
authors.initials: R
authors.lastname: Da Cas
authors.forename: G
authors.initials: G
authors.lastname: Saggiomo
authors.forename: R
authors.initials: R
authors.lastname: Di Nardo
authors.forename: G
authors.initials: G
authors.lastname: Traversa
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D016001:Confidence Intervals; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009544:Niflumic Acid / Q000009:adverse effects*; D016017:Odds Ratio; D012307:Risk Factors
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D009544:Niflumic Acid