title: Are concerns over right laparoscopic donor nephrectomy unwarranted?
abstract: OBJECTIVE
  To examine the ability of several large, experienced transplantation centers to perform right-sided laparoscopic donor nephrectomy safely with equivalent long-term renal allograft function.
  
  
  BACKGROUND
  Early reports noted a higher incidence of renal vein thrombosis and eventual graft loss. However, exclusion of right-sided donors would deprive a significant proportion of donors a laparoscopically harvested graft.
  
  
  METHODS
  A retrospective review was performed among 97 patients from seven centers performing right-sided laparoscopic donor nephrectomy. Surgical and postoperative demographic factors were evaluated. Complications were identified and long-term renal allograft function was compared with historical left-sided laparoscopic donor nephrectomy cohorts.
  
  
  RESULTS
  Right laparoscopic donor nephrectomy was performed for varying reasons, including multiple left renal arteries or veins, smaller right kidney, or cystic right renal mass. Mean surgical time was 235.0 +/- 66.7 minutes, with a mean blood loss of 139 +/- 165.8 mL. Conversion was required in three patients secondary to bleeding or anatomical anomalies. Mean warm ischemic time was limited at 238 +/- 112 seconds. Return to diet was achieved on average after 7.5 +/- 2.3 hours, with mean discharge at 54.6 +/- 22.8 hours. Two grafts were lost during the early experience of these centers to renal vein thrombosis. Both surgical and postoperative complications were limited, with few long-term adverse effects. Mean serum creatinine levels were higher than open and left laparoscopic donor nephrectomy on postoperative day 1, but at all remaining intervals the right laparoscopic donors had equivalent creatinine values.
  
  
  CONCLUSIONS
  These results confirm that right laparoscopic donor nephrectomy provides similar patient benefits, including early return to diet and discharge. Long-term creatinine values were no higher than in traditional open donor or left laparoscopic donor cohorts. These results establish that early concerns about high thrombosis rates are not supported by a multiinstitutional review of laparoscopic right donor nephrectomies.
authors.affiliation: Department of Surgery, University of Cincinnati, Cincinnati, Ohio, USA.
authors.forename: J F
authors.initials: JF
authors.lastname: Buell
authors.forename: M
authors.initials: M
authors.lastname: Edye
authors.forename: M
authors.initials: M
authors.lastname: Johnson
authors.forename: C
authors.initials: C
authors.lastname: Li
authors.forename: A
authors.initials: A
authors.lastname: Koffron
authors.forename: E
authors.initials: E
authors.lastname: Cho
authors.forename: P
authors.initials: P
authors.lastname: Kuo
authors.forename: L
authors.initials: L
authors.lastname: Johnson
authors.forename: M
authors.initials: M
authors.lastname: Hanaway
authors.forename: S R
authors.initials: SR
authors.lastname: Potter
authors.forename: D S
authors.initials: DS
authors.lastname: Bruce
authors.forename: D C
authors.initials: DC
authors.lastname: Cronin
authors.forename: K A
authors.initials: KA
authors.lastname: Newell
authors.forename: J
authors.initials: J
authors.lastname: Leventhal
authors.forename: S
authors.initials: S
authors.lastname: Jacobs
authors.forename: E S
authors.initials: ES
authors.lastname: Woodle
authors.forename: S T
authors.initials: ST
authors.lastname: Bartlett
authors.forename: J L
authors.initials: JL
authors.lastname: Flowers
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D010535:Laparoscopy; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D012189:Retrospective Studies
chemical_list: D003404:Creatinine