Update in podocyte biology.
Knowledge of podocyte biology is growing rapidly. Podocytes are crucially involved in most hereditary diseases affecting the glomerulus, which all exhibit podocyte-specific defects, that is, foot process effacement and protein leakage. Efforts to understand molecular mechanisms causing these derangements are increasingly successful and will allow a better targeting of interventions to halt the progression of chronic renal disease.
Endlich
K
K
Institute for Anatomy and Cell Biology, University of Heidelberg, Heidelberg, Germany.
Kriz
W
W
Witzgall
R
R
D004847:Epithelial Cells / Q000473:pathology / Q000502:physiology; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D007678:Kidney Glomerulus / Q000473:pathology / Q000502:physiology