title: [The significance of polymerase chain reaction in diagnosing causes of subfebrility in children and adolescents].
abstract: Examination of 37 children and adolescents with long-term subfebrility and other manifestations of intoxication without local pathological changes included blood test (polymerase chain reaction) for M. tuberculosis. Tuberculous bacteriemia was discovered in 16(43.2%) cases. Non-acute onset and long-lasting intoxication, rejection of other reasons, tuberculin sensitivity, reduction or disappearance of the intoxication in antituberculous treatment, negative results of repeated PCR for M-tuberculosis gave grounds to suspect active tuberculosis in 13 children of 16. Clinical and x-ray picture corresponded to tuberculous intoxication in children and adolescents.
authors.forename: I F
authors.initials: IF
authors.lastname: Kopylova
authors.forename: Z D
authors.initials: ZD
authors.lastname: Narysheva
authors.forename: I A
authors.initials: IA
authors.lastname: Leliukh
authors.forename: O A
authors.initials: OA
authors.lastname: Timoshchuk
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000235:genetics*; D016133:Polymerase Chain Reaction; D012737:Sex Factors; D013997:Time Factors; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents