Acute cholestatic hepatitis caused by a probable allergic reaction to paracetamol in an adolescent.
We reported on an adolescent who suffered from cholestatic hepatitis after taking a low dose of paracetamol. It was suspected that the condition was brought about by an allergic reaction to paracetamol. Paracetamol is one of the representative intrinsic hepatotoxic drugs. There have been only a few reports on liver damage due to an allergic reaction to paracetamol. There is a need to call attention to this particular reaction.
Shinzawa
H
H
The Second Department of Internal Medicine, Yamagata University School of Medicine, Japan. shinzawa@okitama-hp.or.jp
Togashi
H
H
Sugahara
K
K
Ishibashi
M
M
Terui
Y
Y
Aoki
M
M
Mitsuhashi
H
H
Matsuo
T
T
Watanabe
H
H
Abe
T
T
Ohno
S
S
Saito
K
K
Saito
T
T
Yamada
N
N
Takahashi
T
T
Horiuchi
R
R
D000082:Acetaminophen / Q000009:adverse effects*; D000208:Acute Disease; D000293:Adolescent; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects*; D001663:Bilirubin / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D002780:Cholestasis, Intrahepatic / Q000139:chemically induced*; D004342:Drug Hypersensitivity / Q000473:pathology; D005260:Female; D006525:Hepatitis, Viral, Human / Q000821:virology; D006801:Humans; D008111:Liver Function Tests; D008213:Lymphocyte Activation
D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen; D001663:Bilirubin