Altered intracellular processing and release of neuropeptide Y due to leucine 7 to proline 7 polymorphism in the signal peptide of preproneuropeptide Y in humans.
Kallio
J
J
Department of Pharmacology and Clinical Pharmacology, University of Turku, Turku, Finland. jaana.kallio@utu.fi
Pesonen
U
U
Kaipio
K
K
Karvonen
M K
MK
Jaakkola
U
U
Heinonen
O J
OJ
Uusitupa
M I
MI
Koulu
M
M
D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D004730:Endothelium, Vascular / Q000166:cytology; D015444:Exercise / Q000502:physiology*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005838:Genotype; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D018613:Microscopy, Confocal; D008954:Models, Biological; D009478:Neuropeptide Y / Q000097:blood / Q000235:genetics / Q000378:metabolism*; D011110:Polymorphism, Genetic; D011498:Protein Precursors / Q000235:genetics / Q000378:metabolism*; D011499:Protein Processing, Post-Translational; D021382:Protein Sorting Signals / Q000235:genetics*
D005230:Fatty Acids, Nonesterified; D009478:Neuropeptide Y; D011498:Protein Precursors; D021382:Protein Sorting Signals; C042084:preproneuropeptide Y