Anesthetic management of toxic epidermal necrolysis: report of three adult cases.
Toxic epidermal necrolysis is a rare but acute life-threatening syndrome in which the epidermis blisters and peels in large sheets. In general, patients with this syndrome are managed as severe second-degree burn patients, but special consideration should be given to mucous membrane involvement that reduces fluid intake and worsens the fluid deficit, systemic involvement that makes these patients hemodynamically unstable, and progression of cutaneous lesions that enhances the risk of infection and sepsis.
Rabito
S F
SF
Department of Anesthesiology and Pain Management, Cook County Hospital, Chicago, IL 60612, USA. Rabito@IX.netcom.com
Sultana
S
S
Konefal
T S
TS
Candido
K D
KD
D000328:Adult; D000758:Anesthesia; D000890:Anti-Infective Agents / Q000009:adverse effects; D000927:Anticonvulsants / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D010672:Phenytoin / Q000009:adverse effects; D013262:Stevens-Johnson Syndrome / Q000150:complications / Q000628:therapy*; D013449:Sulfonamides / Q000009:adverse effects; D014777:Virus Diseases / Q000150:complications
D000890:Anti-Infective Agents; D000927:Anticonvulsants; D013449:Sulfonamides; D010672:Phenytoin