African trypanosomes in the 21st century: what is their future in science and in health?
The African trypanosomes remain well recognised for their role as an interesting model eukaryote for basic science, but are loosing ground in their ability to contribute to understanding common cellular mechanisms. At the same time, the diseases they cause remain as prevalent as ever, but appear increasingly irrelevant in their wider medical, social, economic and political context. What can be done to keep trypanosome biology relevant and vigorous in the 21st century?
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Laboratory of Molecular Parasitology, The Rockefeller University, Box 185, 1230 York Avenue, 10021-6399, New York, NY, USA. george.cross@rockefeller.edu
D017954:Africa South of the Sahara / Q000453:epidemiology; D000818:Animals; D005544:Forecasting; D006801:Humans; D014344:Trypanocidal Agents / Q000627:therapeutic use; D014345:Trypanosoma / Q000145:classification / Q000235:genetics / Q000502:physiology*; D014346:Trypanosoma brucei brucei / Q000187:drug effects / Q000235:genetics / Q000502:physiology; D014353:Trypanosomiasis, African / Q000188:drug therapy / Q000469:parasitology* / Q000635:transmission; D014370:Tsetse Flies / Q000469:parasitology
D014344:Trypanocidal Agents