title: Prevention of axial elongation in myopia by the trace element zinc.
abstract: The effect of the trace element zinc on the change in the axial length and diopters and the variations of activities of superoxide dismutase (SOD) and nitric oxide synthase (NOS), and the content of NO in the retino pigmental epithelium choroid homogenate of the myopic eyes in form-sense-deprived chicks were studied. The results show that zinc can inhibit the elongation of axis oculi and increase the diopters in myopia. Meanwhile, the activities of SOD and NOS and the content of NO are significantly increased compared with the model group, indicating that zinc can be used to prevent and treat myopia to a certain extent.
authors.affiliation: Department of Chemistry, Huazhong University of Science and Technology, Wuhan, China.
authors.forename: X
authors.initials: X
authors.lastname: Huibi
authors.forename: H
authors.initials: H
authors.lastname: Kaixun
authors.forename: G
authors.initials: G
authors.lastname: Qiuhua
authors.forename: Z
authors.initials: Z
authors.lastname: Yushan
authors.forename: H
authors.initials: H
authors.lastname: Xiuxian
mesh_terms: D000818:Animals; D002645:Chickens; D004195:Disease Models, Animal; D009216:Myopia / Q000188:drug therapy / Q000378:metabolism*; D019001:Nitric Oxide Synthase / Q000378:metabolism; D010857:Pigment Epithelium of Eye / Q000201:enzymology / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism; D014131:Trace Elements / Q000378:metabolism*; D015032:Zinc / Q000378:metabolism* / Q000627:therapeutic use
chemical_list: D014131:Trace Elements; D019001:Nitric Oxide Synthase; D013482:Superoxide Dismutase; D015032:Zinc