[Adaptation of the phytopathogenic fungus Fusarium decemcellulare to oxidative stress].
The adaptive response of the phytopathogenic fungus Fusarium decemcellulare to the oxidative stress induced by hydrogen peroxide and juglone (5-hydroxy-1,4-naphthoquinone) was studied. At concentrations higher than 1 mM, H2O2 and juglone completely inhibited the growth of the fungus. The 60-min pretreatment of logarithmic-phase cells with nonlethal concentrations of H2O2 (0.25 mM) and juglone (0.1 mM) led to the development of a resistance to high concentrations of these oxidants. The stationary-phase cells were found to be more resistant to the oxidants than the logarithmic-phase cells. The adaptation of fungal cells to H2O2 and juglone was associated with an increase in the activity of cellular catalase and superoxide dismutase, the main oxidative stress defense of enzymes.
Medentsev
A G
AG
Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, pr. Nauki 5, Pushchino, Moscow Oblast, 142290 Russia. medentsev@ibpm.serpukhov.su
Arinbasarova
A Iu
AIu
Aimenko
V K
VK
D000222:Adaptation, Physiological; D002374:Catalase / Q000378:metabolism; D005670:Fusarium / Q000187:drug effects / Q000201:enzymology / Q000472:pathogenicity / Q000502:physiology*; D006861:Hydrogen Peroxide / Q000494:pharmacology; D009285:Naphthoquinones / Q000494:pharmacology; D018384:Oxidative Stress; D013482:Superoxide Dismutase / Q000378:metabolism
D009285:Naphthoquinones; D006861:Hydrogen Peroxide; D002374:Catalase; D013482:Superoxide Dismutase; C005134:juglone