Constitutive expression of arginase in microvascular endothelial cells counteracts nitric oxide-mediated vasodilatory function.
Zhang
C
C
Department of Medical Physiology, Cardiovascular Research Institute, The Texas A&M University System Health Science Center, College Station, Texas 77843-1114, USA.
Hein
T W
TW
Wang
W
W
Chang
C I
CI
Kuo
L
L
D000241:Adenosine / Q000494:pharmacology; D000818:Animals; D001119:Arginase / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D001160:Arterioles / Q000033:anatomy & histology / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D003331:Coronary Vessels / Q000201:enzymology / Q000502:physiology*; D000518:Eflornithine / Q000494:pharmacology; D004730:Endothelium, Vascular / Q000166:cytology / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D007150:Immunohistochemistry; D009569:Nitric Oxide / Q000378:metabolism*; D019001:Nitric Oxide Synthase / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012701:Serotonin / Q000494:pharmacology; D013552:Swine; D014664:Vasodilation; D019323:omega-N-Methylarginine / Q000494:pharmacology
D004791:Enzyme Inhibitors; D019323:omega-N-Methylarginine; D009569:Nitric Oxide; D012701:Serotonin; D019001:Nitric Oxide Synthase; D001119:Arginase; D000241:Adenosine; D000518:Eflornithine