title: Nanoscale atmospheric pressure laser ablation-mass spectrometry.
abstract: We describe an atmospheric pressure nanosampling interface for mass spectrometry based on near-field laser ablation. Pulsed laser radiation is delivered to the sample surface through a near-field optical probe, and the ablation plume is sampled through a capillary orifice and analyzed by standard MS methods. A spatial resolution of less than 200 nm and a sensitivity below 2 amol is demonstrated.
authors.affiliation: Department of Chemistry, Swiss Federal Institute of Technology (ETH), Zürich.
authors.forename: R
authors.initials: R
authors.lastname: Stöckle
authors.forename: P
authors.initials: P
authors.lastname: Setz
authors.forename: V
authors.initials: V
authors.lastname: Deckert
authors.forename: T
authors.initials: T
authors.lastname: Lippert
authors.forename: A
authors.initials: A
authors.lastname: Wokaun
authors.forename: R
authors.initials: R
authors.lastname: Zenobi