Pancreatic acinar cell carcinoma.
Acinar cell carcinomas (ACCs) are rare neoplasms that represent less than 2% of all exocrine tumors of the pancreas. Although they occur more often in adults between the 5th and 7th decades of life, a few cases have been reported in children. Histologically, ACCs can resemble islet cell tumors, but they differ in their ultrastructural and immunohistochemical features. Although ACCs present a bland histology, they are highly malignant and the survival of patients with these tumors, even though better than that of those with ductal cell carcinomas, is generally poor.
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The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
D014408:Biomarkers, Tumor / Q000032:analysis; D018267:Carcinoma, Acinar Cell / Q000737:chemistry / Q000201:enzymology / Q000401:mortality / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D015388:Organelles / Q000648:ultrastructure; D010190:Pancreatic Neoplasms / Q000737:chemistry / Q000401:mortality / Q000473:pathology*; D022142:Secretory Vesicles / Q000648:ultrastructure; D015996:Survival Rate
D014408:Biomarkers, Tumor