[Unexpected formation of spiro(benzofuran-2,2'-(1,4)benzothiazines) from aurones].
The reaction between (Z)-2-benzylidene-3-coumaranones (aurones) 4B, 2-aminothiophenol and sodium ethanolate does not give the expected benzofuro[2,3-c][1,5]benzothiazepines 7, but yields the spiro compounds 8. Their structures are confirmed by an X-ray analysis.
Görlitzer
K
K
Institut für Pharmazeutische Chemie, Technischen Universität Braunschweig, Germany.
Wichers
M
M
Jones
P G
PG
D001572:Benzofurans / Q000138:chemical synthesis*; D018360:Crystallography, X-Ray; D004110:Diltiazem / Q000031:analogs & derivatives / Q000138:chemical synthesis; D007202:Indicators and Reagents; D008968:Molecular Conformation; D013843:Thiazines / Q000138:chemical synthesis*
D001572:Benzofurans; D007202:Indicators and Reagents; D013843:Thiazines; D004110:Diltiazem