title: [Activation of hemostasis in patients with chronic cholecystitis].
abstract: The aim of the study was to evaluate the influence of chronic cholecystitis on haemostasis. The study was conducted on 48 patients suffering from chronic cholecystolithiasis admitted for cholecystectomy to the Department of Surgery Regional Hospital in Białystok. The control group consisted of 25 healthy subjects in this same age range. As a result of the study we found out that patients with chronic cholecystitis had hypercoagulability characterised by increase plasma concentrations of the sensitive markers of haemostasis: prothrombin fragments (F1 + 2), thrombin/antithrombin complex (TAT) and D-dimer.
authors.affiliation: Klinika Hematologii AM w Białymstoku.
authors.forename: J
authors.initials: J
authors.lastname: Kłoczko
authors.forename: J J
authors.initials: JJ
authors.lastname: Lewandowski
authors.forename: M
authors.initials: M
authors.lastname: Galar
authors.forename: K
authors.initials: K
authors.lastname: Mazgajska-Barczyk
authors.forename: M
authors.initials: M
authors.lastname: Panek
mesh_terms: D000328:Adult; D000368:Aged; D000990:Antithrombin III; D015415:Biomarkers / Q000097:blood; D002769:Cholelithiasis / Q000097:blood / Q000150:complications*; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010446:Peptide Fragments / Q000097:blood; D010447:Peptide Hydrolases / Q000097:blood; D011498:Protein Precursors / Q000097:blood; D011516:Prothrombin; D019851:Thrombophilia / Q000097:blood / Q000175:diagnosis / Q000209:etiology*
chemical_list: D015415:Biomarkers; D005338:Fibrin Fibrinogen Degradation Products; D010446:Peptide Fragments; D011498:Protein Precursors; C046193:antithrombin III-protease complex; C036309:fibrin fragment D; C029733:prothrombin fragment 1; C044183:prothrombin fragment 2; D000990:Antithrombin III; D011516:Prothrombin; D010447:Peptide Hydrolases