title: A community-dwelling sample of people with Parkinson's disease: characteristics of fallers and non-fallers.
abstract: BACKGROUND
  people with Parkinson's disease often fall.
  
  
  OBJECTIVE
  to report the frequency of falls and characteristics of fallers and non-fallers in a community-based sample of people with Parkinson's disease.
  
  
  METHODS
  we administered a battery of standardized tests in the home and the laboratory.
  
  
  RESULTS
  we recruited 63 people with Parkinson's disease through general practices. Forty (64%, 95% confidence interval 51-74%) had fallen in the previous 12 months. Many factors associated with falling in the general population were associated with Parkinson's disease fallers (e.g. use of multiple medication and greater physical disability). Fallers were more likely to be depressed and anxious than non-fallers. Condition-specific factors associated with falling included greater disease severity (although there were exceptions) and more marked response to levodopa treatment, including more dyskinesia and on-off phenomena. Fallers took more steps to complete a test of mobility. They also had a shorter functional reach and greater postural sway whilst completing a dual task than non-fallers.
  
  
  CONCLUSIONS
  this community-based study confirms the high risk of falling in Parkinson's disease. Our results suggest that disease-specific factors contribute to the increased risk and that there is scope for specific therapeutic interventions.
authors.affiliation: University Medical Statistics Department, Southampton General Hospital, UK. A.M.Ashburn@soton.ac.uk
authors.forename: A
authors.initials: A
authors.lastname: Ashburn
authors.forename: E
authors.initials: E
authors.lastname: Stack
authors.forename: R M
authors.initials: RM
authors.lastname: Pickering
authors.forename: C D
authors.initials: CD
authors.lastname: Ward
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control / Q000706:statistics & numerical data*; D000203:Activities of Daily Living / Q000145:classification; D000368:Aged; D000369:Aged, 80 and over; D001008:Anxiety Disorders / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000453:epidemiology; D004739:England / Q000453:epidemiology; D005260:Female; D020233:Gait Disorders, Neurologic / Q000453:epidemiology*; D015577:Geriatric Assessment / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000453:epidemiology*; D012307:Risk Factors