title: [Persistent hyperglycemia and hyperinsulinemia in a newborn infant].
abstract: Management of neonatal hyperglycemia is complex, especially in immature newborns. Etiology is diverse, the most frequent cause being iatrogeny. Neonatal diabetes mellitus is a rare cause of hyperglycemia during the first days of life. Insulin treatment is sometimes required to control the condition. When insulin requirements exceed 2I U/kg/day insulin resistance syndrome should be suspected. We present the case of a newborn infant with Donohue syndrome, or leprechaunism, which is a rare, genetically determined dysmorphic syndrome leading to significant insulin resistance.
authors.affiliation: Area de Pediatría, Hospital Costa del Sol. Marbella, Málaga. leotapiaceb@hotmail.com
authors.forename: L
authors.initials: L
authors.lastname: Tapia Ceballos
authors.forename: J
authors.initials: J
authors.lastname: Romero Sánchez
authors.forename: B
authors.initials: B
authors.lastname: Picazo Angelin
authors.forename: R
authors.initials: R
authors.lastname: Díaz Cabrera
authors.forename: J
authors.initials: J
authors.lastname: Romero González
mesh_terms: D000015:Abnormalities, Multiple; D006801:Humans; D006943:Hyperglycemia / Q000150:complications* / Q000209:etiology; D006946:Hyperinsulinism / Q000150:complications* / Q000209:etiology; D007231:Infant, Newborn; D007333:Insulin Resistance; D008297:Male; D013577:Syndrome