Molecular cloning of PalBH, a mammalian homologue of the Aspergillus atypical calpain PalB.
A mammalian homologue of the Aspergillus atypical calpain PalB, PalBH, was identified and its cDNA sequences were determined in human and mouse. The PalBH mRNA was expressed nearly ubiquitously throughout mammalian tissues. When expressed in COS cells, PalBH was enriched in the nucleus, suggesting its role is distinct from that of conventional calpains.
Futai
E
E
Institute of Molecular and Cellular Biosciences, University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.
Kubo
T
T
Sorimachi
H
H
Suzuki
K
K
Maeda
T
T
D000595:Amino Acid Sequence; D000818:Animals; D001230:Aspergillus / Q000201:enzymology / Q000235:genetics; D001483:Base Sequence; D002154:Calpain / Q000737:chemistry / Q000235:genetics*; D003001:Cloning, Molecular; D003546:Cysteine Endopeptidases / Q000737:chemistry / Q000235:genetics; D005656:Fungal Proteins; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
D005656:Fungal Proteins; D002154:Calpain; D003546:Cysteine Endopeptidases; C097042:PalB protein, Aspergillus nidulans