title: Acute pancreatitis associated with interferon alpha therapy for chronic myelogenous leukemia.
abstract: Acute pancreatitis related to interferon alpha therapy is very rare. We report two patients with chronic myelogenous leukemia (CML) who developed acute pancreatitis following treatment with interferon alpha. A review of the literature on the association of pancreatitis and interferon alpha is provided. Possible pathophysiologic mechanisms are also discussed.
authors.affiliation: Department of Leukemia, the University of Texas MD Anderson Cancer Center, Houston, Texas 77030 USA.
authors.forename: N M
authors.initials: NM
authors.lastname: Tannir
authors.forename: M
authors.initials: M
authors.lastname: Talpaz
authors.forename: H
authors.initials: H
authors.lastname: Ghazal
authors.forename: S
authors.initials: S
authors.lastname: Proothi
authors.forename: H M
authors.initials: HM
authors.lastname: Kantarjian
mesh_terms: D000208:Acute Disease; D000328:Adult; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000188:drug therapy; D008297:Male; D010195:Pancreatitis / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D016898:Interferon-alpha