Differences in the gut bacterial flora of healthy and milk-hypersensitive adults, as measured by fluorescence in situ hybridization.
We enumerated the predominant gut genera from fecal samples of nine healthy and eight milk-hypersensitive adults both before and after 4 weeks Lactobacillus rhamnosus GG (LGG) supplementation. The anaerobic intestinal microflora of milk-hypersensitive adults was found to resemble that of healthy adults. LGG-consumption resulted in a significant increase in the number of bifidobacteria in healthy but not in milk-hypersensitive subjects, as well as a general increase in bacterial numbers in all other bacterial genera tested in both groups. In conclusion, the composition of the gut microbiota in milk-hypersensitive adults appears to be normal. LGG may have potential in reinforcing the endogenous flora.
Apostolou
E
E
Department of Biochemistry and Food Chemistry, FIN-20014 University of Turku, Finland.
Pelto
L
L
Kirjavainen
P V
PV
Isolauri
E
E
Salminen
S J
SJ
Gibson
G R
GR
D000328:Adult; D001421:Bacteria, Anaerobic / Q000254:growth & development / Q000302:isolation & purification*; D001644:Bifidobacterium / Q000302:isolation & purification; D005243:Feces / Q000382:microbiology*; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007778:Lactobacillus / Q000254:growth & development / Q000302:isolation & purification; D008297:Male; D016269:Milk Hypersensitivity / Q000382:microbiology*; D019936:Probiotics / Q000008:administration & dosage