Structures of azaspiracid analogs, azaspiracid-4 and azaspiracid-5, causative toxins of azaspiracid poisoning in Europe.
Two new analogs of azaspiracid, azaspiracid-4 and azaspiracid-5, isolated from the mussel Mytilus edulis, involved in a newly emerged shellfish poisoning in Europe were determined to be 3-hydroxy-22-demethylazaspiracid and 23-hydroxy-22-demethylazaspiracid, respectively.
Ofuji
K
K
Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.
Satake
M
M
Mcmahon
T
T
James
K J
KJ
Naoki
H
H
Oshima
Y
Y
Yasumoto
T
T
D000818:Animals; D049872:Bivalvia / Q000737:chemistry*; D005060:Europe; D005517:Foodborne Diseases; D006575:Heterocyclic Compounds, 3-Ring / Q000737:chemistry*; D006801:Humans; D008387:Marine Toxins / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D013141:Spiro Compounds / Q000737:chemistry* / Q000302:isolation & purification; D000095702:Polyether Toxins
D006575:Heterocyclic Compounds, 3-Ring; D008387:Marine Toxins; D013141:Spiro Compounds; C437734:23-hydroxy-22-demethylazaspiracid; C437733:3-hydroxy-22-demethylazaspiracid; C406592:azaspiracid; D000095702:Polyether Toxins