title: [New developments in MRI of the thorax].
abstract: MRI was not used often for lung imaging due to technical and physical limitations. Recent developments have considerably improved anatomical MR imaging, and at the same time new perspectives for functional imaging emerged. They consist of functional investigations of pulmonary perfusion (contrast agents, MR angiography) and ventilation (inhaled contrast aerosols, oxygen, hyperpolarized noble gases [He-3, Xe-129] and fluorinated gases [SF6]). New parameters can be measured: homogeneity of ventilation, lung volumes, airspace size, intrapulmonary oxygen partial pressure, dynamic ventilation distribution and ventilation/perfusion ratios. MRI-inherent advantages are: lack of radiation, high spatial and temporal resolution, and a broad range of functional information. MRI of lung ventilation seems to be more sensitive in the detection of ventilation defects than scintigraphy, CT or pulmonary function tests. By combining the new strategies the radiologist will be capable to improve specificity of the investigations and to characterize lung function impairments. The joint assessment of ventilation and perfusion will play a major role in this development.
authors.affiliation: Klinik und Poliklinik für Radiologie, Johannes-Gutenberg-Universität Mainz, Langenbeckstrasse 1, 55131 Mainz. kauczor@radiologie.klinik.uni-mainz.de
authors.forename: H U
authors.initials: HU
authors.lastname: Kauczor
authors.forename: C P
authors.initials: CP
authors.lastname: Heussel
authors.forename: W G
authors.initials: WG
authors.lastname: Schreiber
authors.forename: K F
authors.initials: KF
authors.lastname: Kreitner
mesh_terms: D003287:Contrast Media; D006801:Humans; D007089:Image Enhancement; D008168:Lung / Q000473:pathology*; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000473:pathology; D012680:Sensitivity and Specificity; D014692:Ventilation-Perfusion Ratio / Q000502:physiology
chemical_list: D003287:Contrast Media