title: Locoregionally recurrent breast cancer: incidence, risk factors and survival.
abstract: Locoregional recurrence (LRR) after therapy for early breast cancer is common. Patients with LRR can suffer both local consequences and symptoms of metastatic disease, as LRR is an independent predictor of subsequent distant metastases. Much of the available data on LRR is derived from small, single institution, retrospective studies, so marked differences in the incidence rates for LRR, it's risk factors and subsequent systemic recurrence are reported. The purpose of this review was to try and collate this data in a format that would be useful for both clinicians and their patients.
authors.affiliation: Department of Medical Oncology, Christie Hospital, Wilmslow Road, Manchester, UK. clemonde@breathemail.net
authors.forename: M
authors.initials: M
authors.lastname: Clemons
authors.forename: S
authors.initials: S
authors.lastname: Danson
authors.forename: T
authors.initials: T
authors.lastname: Hamilton
authors.forename: P
authors.initials: P
authors.lastname: Goss
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D015994:Incidence; D008408:Mastectomy; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000473:pathology*; D011379:Prognosis; D012307:Risk Factors; D016019:Survival Analysis