[Reduction of hematogenous infection in HIV positive patients following highly active antiretroviral therapy].
BACKGROUND
Bloodstream infections have probably decreased in HIV patients since highly active antiretroviral therapy (HAART) usage.


METHODS
Hematogenous infections, including mycobacteria and fungi in HIV patients, stratified into two periods (I: 1995-1996 and II: 1997-1998) were included to evaluate changes attributable to HAART.


RESULTS
226 episodes were attended (incidence: 38.8 in period I and 15.3 in period II; p < 0.01). A significant decrease was observed in immunosuppression related microorganisms. HAART usage increased from 6.4% in period I to 31.2% in period II. Immunological parameters of HIV patients significantly improved in period II.


CONCLUSIONS
Hematogenous infections have significantly decreased in HIV patients since the use of HAART.
Luisa Pedro-Botet
M
M
Unidades de Enfermedades Infecciosas. Hospital Universitari Germans Trias i Pujol. Badalona. Barcelona. umi@ns.hugtip.es
Maria Mòdol
J
J
Vallés
X
X
Reynaga
E
E
Romeu
J
J
Juan
M
M
Sopena
N
N
Sabriá Leal
M
M
D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology*; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D008297:Male; D018805:Sepsis / Q000453:epidemiology*
D019380:Anti-HIV Agents