Flexyx Neurotherapy System in the treatment of traumatic brain injury: an initial evaluation.
OBJECTIVE
To conduct a preliminary experimental evaluation of the potential efficacy of Flexyx Neurotherapy System (FNS), an innovative electroencephalography (EEG)-based therapy used clinically in the treatment of traumatic brain injury (TBI).


METHODS
Twelve people aged 21 to 53 who had experienced mild to moderately severe closed head injury at least 12 months previously and who reported substantial cognitive difficulties after injury, which interfered with their functioning.


METHODS
Participants were randomly assigned to an immediate treatment group or a wait-list control group and received 25 sessions of FNS treatment. They were assessed at pretreatment, posttreatment, and follow-up with standardized neuropsychological and mood measures.


RESULTS
Comparison of the two groups on outcome measures indicated improvement after treatment for participants' reports of depression, fatigue, and other problematic symptoms, as well as for some measures of cognitive functioning. Most participants experienced meaningful improvement in occupational and social functioning.


CONCLUSIONS
On the basis of these results, FNS appears to be a promising new therapy for TBI and merits more extensive evaluation.
Schoenberger
N E
NE
Kessler Medical Rehabilitation Research and Education Corporation, West Orange, New Jersey, USA. nschoen1@midsouth.rr.com
Shif
S C
SC
Esty
M L
ML
Ochs
L
L
Matheis
R J
RJ
D000328:Adult; D000339:Affect; D001676:Biofeedback, Psychology / Q000379:methods*; D001930:Brain Injuries / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology / Q000534:rehabilitation*; D003072:Cognition Disorders / Q000209:etiology; D003863:Depression / Q000209:etiology; D004569:Electroencephalography / Q000379:methods*; D005221:Fatigue / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D016896:Treatment Outcome