title: Fluorescent cyclodextrin immobilized on a cellulose membrane as a chemosensor system for detecting molecules.
abstract: Dansyl glutamate-modified cyclodextrin (DnsGlu-beta-CD) was prepared as a fluorescent host, which is capable of being immobilized on a cellulose membrane (DnsGlu-beta-CD-membrane). The fluorescence intensity of DnsGlu-beta-CD decreased with increasing concentration of guest molecules, indicating that the host changes the location of the dansyl group from inside to outside the cyclodextrin cavity upon guest accommodation. Similar guest-induced decrease in the fluorescence intensity was observed for DnsGlu-beta-CD immobilized to a cellulose membrane. This result demonstrates that the cellulose membrane may be used as a practical supporting material of various chromophore-modified cyclodextrins and that DnsGlu-beta-CD-membrane is useful as a novel disposable chemosensor for molecules.
authors.affiliation: Department of Bioengineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Tanabe
authors.forename: K
authors.initials: K
authors.lastname: Touma
authors.forename: K
authors.initials: K
authors.lastname: Hamasaki
authors.forename: A
authors.initials: A
authors.lastname: Ueno