title: New taxane analogues from the needles of Taxus canadensis.
abstract: Eight minor taxanes have been identified for the first time in Taxus canadensis needles. Four of these metabolites are new taxane analogues: 7-acetyl-10-deacetyltaxol (1), 2'-acetyl-7-epi-cephalomannine (2), 10-deacetyl-10-oxo-7-epi-cephalomannine (3), and 10-acetylglycollylbaccatin VI (4).
authors.affiliation: Human Health Research Center, INRS-Institut Armand-Frappier, Université du Québec, 531 Boulevard des Prairies, Laval, Québec, Canada, H7V 1 B7.
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: F
authors.initials: F
authors.lastname: Sauriol
authors.forename: O
authors.initials: O
authors.lastname: Mamer
authors.forename: X L
authors.initials: XL
authors.lastname: You
authors.forename: M A
authors.initials: MA
authors.lastname: Alaoui-Jamali
authors.forename: G
authors.initials: G
authors.lastname: Batist
authors.forename: L O
authors.initials: LO
authors.lastname: Zamir
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001943:Breast Neoplasms / Q000473:pathology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014197:Trees; D014407:Tumor Cells, Cultured
chemical_list: D000470:Alkaloids