title: Outcome of surgical intervention for rectoneovaginal fistulas in Mayer-Rokitansky-Kuester-Hauser syndrome.
abstract: Creation of a neovagina to treat vaginal atresia or aplasia in Mayer-Rokitansky-Kuester-Hauser syndrome must always be followed by long-term application of dilators to avoid shrinkage. However, rectoneovaginal fistulas are caused by chronic alteration and consecutive necrosis of the posterior neovaginal wall. We evaluated retrospectively the postoperative outcome of rectal wall and neovaginal reconstruction using a standardized surgical technique in an exclusive collection of women. Eight women with a mean age of 28 years (range 22-31 years) were treated for rectoneovaginal fistulas in our clinic. Preoperatively, proctoscopy, sphincter manometry, endoluminal rectal ultrasonography, and colonoscopy were performed; and regular postoperative follow-up by digital examination and rectoscopy were obligate. The standard surgical procedure via a perineal approach included fistulectomy and closure of the mucosa and rectal wall followed by a levatorplasty. All but one woman had a temporary colostomy. After 2 weeks the patients were allowed to wear vaginal dilators of a smaller size. Within the mean follow-up period of 20 months, reintervention was necessary twice because of late fistula relapse detected by proctoscopy, barium enema, and subjective symptoms. Morbidity was 25% (n = 2) due to secondary superficial wound healing or urinary tract infection. The average time of the hospital stay was 13 days (10-14 days). One patient complained of vaginal shrinkage and underwent local estrogen therapy with a good functional result 3 months later. Proper fistulectomy and surgical reconstruction with interpositioning of well perfused muscle layers achieved good functional outcome with an acceptable number of minor morbidities. Local estrogen treatment is helpful for avoiding scarification and decreasing the neovaginal size.
authors.affiliation: Department of Surgery, University of Muenster, 48129 Muenster, Germany. schult@uni-muenster.de
authors.forename: M
authors.initials: M
authors.lastname: Schult
authors.forename: H H
authors.initials: HH
authors.lastname: Wolters
authors.forename: R J
authors.initials: RJ
authors.lastname: Lellé
authors.forename: G
authors.initials: G
authors.lastname: Winde
authors.forename: N
authors.initials: N
authors.lastname: Senninger
mesh_terms: D000328:Adult; D004106:Dilatation; D005260:Female; D006801:Humans; D012006:Rectovaginal Fistula / Q000601:surgery*; D012008:Recurrence; D012086:Reoperation; D013577:Syndrome; D016896:Treatment Outcome; D014621:Vagina / Q000002:abnormalities*