title: [Clinico-immunological variants of the course of chronic pancreatitis].
abstract: OBJECTIVE
  To study relationships between clinical course of chronic pancreatitis (CP) and humoral immunity in CP patients.
  
  
  METHODS
  Humoral immunity to structural and secretory pancreatic components and some phlogogenic factors of humoral and cellular origin as well as distribution of HLA antigens were studied in 115 CP patients.
  
  
  RESULTS
  Two variants of CP course were identified: immunologically dependent and immunologically independent. These variants have typical clinical, laboratory, immunological and immunogenetic differences.
  
  
  CONCLUSIONS
  Identification of immunologically dependent variant of CP has both fundamental and practical value as it enables more precise prognosis of the disease clinical course and differential approach to its treatment.
authors.forename: D I
authors.initials: DI
authors.lastname: Trukhan
mesh_terms: D000936:Antigen-Antibody Complex / Q000032:analysis*; D002908:Chronic Disease; D003165:Complement System Proteins / Q000032:analysis*; D003937:Diagnosis, Differential; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D005779:Immunodiffusion; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D010195:Pancreatitis / Q000175:diagnosis / Q000276:immunology*; D019512:Pancreatitis, Alcoholic / Q000175:diagnosis / Q000276:immunology; D010783:Photometry; D011379:Prognosis
chemical_list: D000936:Antigen-Antibody Complex; D006680:HLA Antigens; D007136:Immunoglobulins; D003165:Complement System Proteins