title: [Immunosuppressive effects of pathogenic gram-negative bacteria].
abstract: The review deals with the Immunosuppressive effects of virulent gram-negative bacteria (Salmonella, Shigela, Pseudomonas aeruginosa), with the importance of these effects for the bacteria to survive in the infected body. The above bacteria affect the immunity system in a different way, yet have common features. They are characterized by the occurrence of endotoxin shock, by the suppression of the phagocytic system and cell-mediated immunity. A significant role in suppressing a cellular immune response is played by the lipopolysaccharide of virulent bacteria that greatly differs from that of nonvirulent strains. The immunosuppressive activity of the bacteria and their lipopolysaccharide is closely related to their virulent properties.
authors.forename: A A
authors.initials: AA
authors.lastname: Vorob'ev
authors.forename: E V
authors.initials: EV
authors.lastname: Borisova
authors.forename: O S
authors.initials: OS
authors.lastname: Molozhavaia
authors.forename: V A
authors.initials: VA
authors.lastname: Borisov
mesh_terms: D000818:Animals; D006090:Gram-Negative Bacteria / Q000276:immunology* / Q000378:metabolism / Q000472:pathogenicity*; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D008070:Lipopolysaccharides / Q000276:immunology* / Q000378:metabolism; D011550:Pseudomonas aeruginosa / Q000276:immunology / Q000378:metabolism / Q000472:pathogenicity; D012475:Salmonella / Q000276:immunology / Q000378:metabolism / Q000472:pathogenicity; D012760:Shigella / Q000276:immunology / Q000378:metabolism / Q000472:pathogenicity; D014774:Virulence
chemical_list: D008070:Lipopolysaccharides