title: Karyotype and prognosis in adult Spanish acute lymphoblastic leukemia.
abstract: The aim of the study was to define the frequency and prognostic significance of acquired chromosomal abnormalities in our adult population and to ascertain whether karyotype represents a significant prognostic factor in adult patients with acute lymphoblastic leukemia (ALL) independently of the new intensive chemotherapy programs and initial clinical characteristics.
authors.forename: M L
authors.initials: ML
authors.lastname: Martín Ramos
authors.forename: J J
authors.initials: JJ
authors.lastname: Lahuerta Palacios
authors.forename: J
authors.initials: J
authors.lastname: Martínez López
authors.forename: M J
authors.initials: MJ
authors.lastname: Gómez Rodríguez
authors.forename: A
authors.initials: A
authors.lastname: Moreno Izquierdo
authors.forename: E
authors.initials: E
authors.lastname: Barreiro Miranda
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002869:Chromosome Aberrations; D020732:Cytogenetic Analysis; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000235:genetics; D011379:Prognosis; D013030:Spain; D015996:Survival Rate