title: Resolution of gingival overgrowth following change from cyclosporin to tacrolimus therapy in a renal transplant patient.
abstract: Gingival overgrowth is a well documented and common side-effect of cyclosporin therapy. Gingival swelling in this condition hinders efficient oral hygiene and is of aesthetic concern to patients. This case report outlines rapid and dramatic reduction in overgrowth when tacrolimus replaced cyclosporin as the immunosuppressive agent in a renal transplant patient with established overgrowth.
authors.affiliation: Division of Restorative Dentistry, School of Dentistry, Queen's University, Belfast.
authors.forename: D S
authors.initials: DS
authors.lastname: Kennedy
authors.forename: G J
authors.initials: GJ
authors.lastname: Linden
mesh_terms: D000328:Adult; D016572:Cyclosporine / Q000009:adverse effects*; D019214:Gingival Overgrowth / Q000139:chemically induced* / Q000628:therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D016030:Kidney Transplantation; D008297:Male; D016559:Tacrolimus / Q000627:therapeutic use*
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D016559:Tacrolimus