Detection of massive transplacental haemorrhage by flow cytometry.
Flow cytometry has been shown to be a more accurate and sensitive method than the Kleihauer-Betke test for the measurement of feto-maternal haemorrhage in Rh(D) incompatibility. This report describes the successful use of flow cytometry to detect and monitor the management of a massive transplacental haemorrhage (105 ml) of fetal Rh(D) positive cells in a Rh(D) negative woman. The report highlights the accuracy and reproducibility of the test and the stability of a blood sample when transferred 596 kilometres to a central testing facility.
Fong
E A
EA
Haematology, Western Australian Centre for Pathology and Medical Research, Nedlands WA, Australia.
Davies
J I
JI
Grey
D E
DE
Reid
P J
PJ
Erber
W N
WN
D000293:Adolescent; D005260:Female; D005331:Fetomaternal Transfusion / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D007231:Infant, Newborn; D007273:Injections, Intramuscular; D011247:Pregnancy; D012203:Rh Isoimmunization / Q000175:diagnosis / Q000628:therapy; D018029:Rho(D) Immune Globulin / Q000627:therapeutic use
D018029:Rho(D) Immune Globulin