title: Effects of gender and age differences on the distribution of bone content in the third lumbar vertebra.
abstract: METHODS
  A cross-sectional study on the distribution of bone mineral content in the third lumbar vertebrae.
  
  
  OBJECTIVE
  To evaluate the effects of age and gender on the distribution of bone mineral content in the third lumbar vertebrae.
  
  
  BACKGROUND
  Compression fractures occur mainly at the vertebral body. Variations in the distribution of bone mass in a vertebra, if undefined, may bias the ability of the acquired bone mineral density values, which was usually measured posteroanteriorly, to predict the risk of fractures.
  
  
  METHODS
  The bone mineral content of the whole L3, including the L3 vertebral body and the posterior segment, was measured using a lateral approach with a dual energy radiograph absorptiometer on 177 healthy Taiwanese adults including 65 men and 55 premenopausal and 57 postmenopausal women.
  
  
  RESULTS
  The proportion of bone mineral content in the vertebral body was significantly lower in premenopausal women than in age-matched men (39.1 +/- 0.9% vs. 50.0 +/- 1.7%, P < 0.0001). Furthermore, whereas postmenopausal women showed a decreased proportion of bone mineral content in the vertebral body with increased age (about -0.0022 per year, P = 0.0001), premenopausal women and men showed a sustained proportion.
  
  
  CONCLUSIONS
  The proportion of bone mineral content distributed in the body of L3 vertebrae was lower in women than in men. The discrepancy of this parameter between the genders was even larger with increased ages.
authors.affiliation: Nuclear Medicine, College of Medicine, National Taiwan University, Taiwan, ROC.
authors.forename: W C
authors.initials: WC
authors.lastname: Cheng
authors.forename: R S
authors.initials: RS
authors.lastname: Yang
authors.forename: S
authors.initials: S
authors.lastname: Huey-Jen Hsu
authors.forename: P U
authors.initials: PU
authors.lastname: Chieng
authors.forename: K S
authors.initials: KS
authors.lastname: Tsai
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016014:Linear Models; D008159:Lumbar Vertebrae / Q000033:anatomy & histology* / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D017698:Postmenopause; D017697:Premenopause; D017678:Sex Distribution