title: Explanatory style and Immunoglobulin A (IgA).
abstract: The construct of explanatory style has been related to numerous aspects of human psychology, including health. Our research has focused on the effects of various psychological variables on the immune system, in particular Immunoglobulin A (IgA). We had participants fill out the Attributional Style Questionnaire (ASQ), the predominant measure of explanatory style, and assayed saliva samples for secretory IgA. No relationship was observed between overall ASQ score and IgA, or composite optimism score and IgA. However, we observed significant negative correlations between both the composite pessimism score and IgA, as well as the hopelessness score and IgA. Pessimistic explanatory style may therefore be related to immune system deficits and poor health.
authors.affiliation: Department of Psychology, Wilkes University. brennan@njneuromed.org
authors.forename: F X
authors.initials: FX
authors.lastname: Brennan
authors.forename: C J
authors.initials: CJ
authors.lastname: Charnetski
mesh_terms: D000293:Adolescent; D000328:Adult; D000917:Antibody Formation / Q000502:physiology*; D005260:Female; D006380:Helplessness, Learned; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D008297:Male; D008934:Mitogens / Q000494:pharmacology; D010551:Personality / Q000502:physiology*; D011795:Surveys and Questionnaires; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D007070:Immunoglobulin A; D008934:Mitogens