title: [Management of necrotizing cellulitis and fasciitis].
abstract: A literature review did not reveal any controlled study on the management of necrotizing fasciitis. Treatment protocol includes: - an immediate or early surgical management with debridement of all necrotic tissue and extensive fasciotomy followed by a surgical reexamination of the infected area in the following days; - an initial antibiotic therapy targeting aerobic Gram-positive and Gram-negative organisms and anaerobes (e.g: amoxicilline-clavulanic acid or vancomycin-metronidazole); - an adequate nutritional support, infusion, and resuscitation; - hyperbaric oxygen therapy may be considered as an associated treatment; but there is no randomized, controlled trial demonstrating its efficacy.
authors.affiliation: Service de dermatologie, hôpital Robert-Debré, Reims, France.
authors.forename: C
authors.initials: C
authors.lastname: Derancourt
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D019115:Fasciitis, Necrotizing / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D011859:Radiography
chemical_list: D000900:Anti-Bacterial Agents