title: Hypopyon uveitis and iris nodules in non-Hodgkin's lymphoma: ocular relapse during systemic remission.
abstract: We report the case history of a patient with peripheral non-Hodgkin's lymphoma in systemic remission, who presented with a pseudohypopyon and iris nodules. Iris biopsy confirmed the presence of intraocular tumour, which subsequently responded to orbital radiation. Ocular remission, however, was soon followed by a systemic relapse, suggesting that the eye may act as a sanctuary site for tumour cells during chemotherapy, and that cells may metastasize from the eye back to the periphery during systemic remission.
authors.affiliation: Rayne Institute, St Thomas' Hospital, London, UK.
authors.forename: D H
authors.initials: DH
authors.lastname: Verity
authors.forename: E M
authors.initials: EM
authors.lastname: Graham
authors.forename: R
authors.initials: R
authors.lastname: Carr
authors.forename: J D
authors.initials: JD
authors.lastname: van der Walt
authors.forename: M R
authors.initials: MR
authors.lastname: Stanford
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005134:Eye Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D006801:Humans; D007498:Iris / Q000473:pathology*; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy*; D008297:Male; D011241:Prednisone / Q000008:administration & dosage; D012008:Recurrence; D012074:Remission Induction; D014605:Uveitis / Q000473:pathology*; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone