title: Salt-sensitivity and other predictors of stress-related cardiovascular reactivity in healthy young males.
abstract: Individuals whose mean arterial blood pressure is depending on oral salt intake are considered salt-sensitive and are at risk of developing essential hypertension. This study investigates the role of salt-sensitivity with respect to systolic blood pressure reactions under standardized mental stress. Forty-three healthy young males, previously characterized as salt-sensitive (n=16) or salt-resistant (n=27) by a dietary regimen, were subjected to multimodal physiological measurement during a computerized stress test and underwent comprehensive psychometrical testing. The most important predictors for systolic blood pressure reactions to stress were the degree of salt-sensitivity, body mass index and psychological characteristics like anxiety. The highest correlations with the degree of salt-sensitivity were found for the parameters age, systolic blood pressure reaction under stress, high frequency band of heart rate variability and two psychological variables. The concept of salt-sensitivity is a novel biological component that might contribute to reactivity research in subjects at high risk for essential hypertension.
authors.affiliation: Department of Psychosomatic Medicine and Psychotherapy, Benjamin Franklin Hospital, Free University of Berlin, Germany.
authors.forename: H C
authors.initials: HC
authors.lastname: Deter
authors.forename: K
authors.initials: K
authors.lastname: Buchholz
authors.forename: U
authors.initials: U
authors.lastname: Schorr
authors.forename: K
authors.initials: K
authors.lastname: Mathiak
authors.forename: A M
authors.initials: AM
authors.lastname: Sharma
mesh_terms: D000328:Adult; D000375:Aging / Q000502:physiology; D001007:Anxiety; D001794:Blood Pressure; D015992:Body Mass Index; D002319:Cardiovascular System / Q000503:physiopathology*; D004351:Drug Resistance; D005544:Forecasting; D006339:Heart Rate; D006801:Humans; D008297:Male; D012016:Reference Values; D012965:Sodium Chloride / Q000494:pharmacology*; D013315:Stress, Psychological / Q000503:physiopathology* / Q000523:psychology; D013599:Systole
chemical_list: D012965:Sodium Chloride