title: Metabolic hoof horn disease. Claw horn disruption.
abstract: Low-quality hoof horn is a frequent underlying cause of lameness in cattle. Because the lesions that are observed are the result of insults that affect horn production at the cellular level, the term claw horn disruption has been proposed to describe the disease process. Although claw horn disruption may result from multiple etiologies, the response of the keratinocytes is relatively nonspecific in that lesions often appear the same regardless of cause. To solve herd problems, the investigation of possible etiologies must be integrated with a basic understanding of the anatomic and physiologic features of hoof horn production.
authors.affiliation: Department of Veterinary Preventive Medicine, Ohio State University, Columbus, USA.
authors.forename: K H
authors.initials: KH
authors.lastname: Hoblet
authors.forename: W
authors.initials: W
authors.lastname: Weiss
mesh_terms: D000138:Acidosis / Q000517:prevention & control / Q000662:veterinary; D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000209:etiology* / Q000378:metabolism; D005534:Foot Diseases / Q000209:etiology / Q000378:metabolism / Q000662:veterinary*; D006724:Hoof and Claw / Q000502:physiology* / Q000503:physiopathology; D007239:Infections / Q000662:veterinary; D007794:Lameness, Animal / Q000209:etiology* / Q000378:metabolism; D012307:Risk Factors