[Preparation and quality control of cross-linked agarose coated activated charcoal (CAAC-II) used as adsorbents for hemoperfusion in artificial liver support].
The preparation and the quality control of cross-linked agarose coated activated (CAAC-II) were described. The crosslinking reagent epichlorohydrin was removed. Investigations indicate that the trace elements such as Pb, Cd, As, Cr, Fe and heavy metals, the pH, NH4+, SO4(2-), and ultraviolet absorbance in sample have met the requirements in Chinese Pharmacopeia and some other relevant standard promulgated by the Ministry of Health. No epichlorohydrin was detected in CAAC-II.
Tang
X
X
Department of Chemistry, Chongqing University of Medical Sciences, Chongqing 400016.
Lu
Y
Y
Yu
H
H
D002214:Capsules; D002606:Charcoal / Q000138:chemical synthesis* / Q000592:standards; D004811:Epichlorohydrin / Q000032:analysis / Q000302:isolation & purification*; D006464:Hemoperfusion; D019164:Liver, Artificial; D011786:Quality Control; D012685:Sepharose; D014131:Trace Elements / Q000032:analysis
D002214:Capsules; D014131:Trace Elements; D004811:Epichlorohydrin; D002606:Charcoal; D012685:Sepharose