title: Unexpected corneal flattening after laser in situ keratomileusis.
abstract: OBJECTIVE
  To perform a statistical study of the variation (flattening) from the surgical radius (sculpted in the corneal stroma) to the final radius of the first surface of the cornea after laser in situ keratomileusis (LASIK) for correction of myopia.
  
  
  METHODS
  The study included 387 eyes with myopia or myopic astigmatism that underwent LASIK using the Nidek EC-5000 excimer laser. Mean age was 34 years (range, 19 to 75 yr). Mean myopia was -5.19 D (range, 0 to -19.00 D) and mean astigmatism was -1.22 D (range, 0 to -5.00 D). The flattening coefficient was defined as: (f) = (Rpost-Rs)/Rs where Rpost. was the corneal radius after surgery (topography performed 1 month after surgery) and Rs was the surgical radius sculpted in the stroma. Mean values and standard deviations of the flattening coefficient were calculated for the 387 eyes for four myopic ranges (0 to -3.00 D, -3.00 to -6.00 D, -6.00 to -9.00 D, and more than -9.00 D), and for three astigmatic ranges (0, -0.25 to -2.00 D, and more than -2.00 D). The correlations between the flattening coefficient and several preoperative ocular variables were obtained.
  
  
  RESULTS
  A linear combination of quasi-independent ocular variables (age, anterior corneal radius, corneal thickness, sphere and cylinder) was found in order to maximize the correlation with the flattening for every range. Values for the correlations between 0.4 to 0.5 were obtained.
  
  
  CONCLUSIONS
  The flattening phenomenon was characterized by a flattening coefficient (f).
authors.affiliation: Departamento de Física Aplicada, Universidad de Cantabria, Spain. gonzaleff@unican.es
authors.forename: F
authors.initials: F
authors.lastname: González
authors.forename: D
authors.initials: D
authors.lastname: Ortiz
authors.forename: J M
authors.initials: JM
authors.lastname: Saiz
authors.forename: F
authors.initials: F
authors.lastname: Moreno
authors.forename: J N
authors.initials: JN
authors.lastname: Fernández del Cotero
mesh_terms: D000328:Adult; D000368:Aged; D001251:Astigmatism / Q000601:surgery; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology; D003319:Corneal Stroma / Q000473:pathology / Q000601:surgery; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D008875:Middle Aged; D009216:Myopia / Q000601:surgery; D013524:Surgical Flaps