title: [Systemic lupus erythematosus in the pregnant patient. Implications for anesthesia].
abstract: A 28-year-old woman with systemic lupus erythematosus and a history of aseptic meningitis, digestive bleeding due to thrombopenia and deep venous thrombosis underwent elective cesarean for transverse presentation at 35 weeks. Preoperative blood work-up showed an antinuclear antibody titre that was slightly positive and steroid treatment was started. Surgery operation was performed with general anesthesia. The outcome was satisfactory even though serious complications can develop during the management of anesthesia in such patients. Systemic lupus erythematosus is a chronic, multisystemic disease that mainly affects women of childbearing age. Antibodies and immunocomplexes play a fundamental role. Given the multiorgan involvement in this disease, preoperative study of the lupus patient should assess all such involvement, including maternal-fetal risk, as well as consider the drug and anesthetic management to be applied. Among the clinical signs that can affect management of anesthesia are the following: aseptic meningitis, high blood pressure, pericarditis, pneumonitis and recurrent venous thrombosis. Anemia, thrombopenia and significantly altered coagulation events are common.
authors.affiliation: ervicio de Anestesiología y Reanimación. Hospital Clínico Universitario Lozano Blesa. Zaragoza. Médico interno residente.
authors.forename: E
authors.initials: E
authors.lastname: Pastor Tomás
authors.forename: J
authors.initials: J
authors.lastname: Guillén Antón
authors.forename: A
authors.initials: A
authors.lastname: Vaquerizo Gareta
authors.forename: P
authors.initials: P
authors.lastname: Lirola Grajales
authors.forename: R
authors.initials: R
authors.lastname: Martínez García
authors.forename: J
authors.initials: J
authors.lastname: Cuartero Lobera
mesh_terms: D000328:Adult; D000768:Anesthesia, General / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000379:methods*; D001327:Autoimmune Diseases / Q000150:complications; D002585:Cesarean Section; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000150:complications; D006801:Humans; D007431:Intraoperative Complications / Q000517:prevention & control*; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D008582:Meningitis, Aseptic / Q000150:complications; D009609:Nitrous Oxide; D011183:Postoperative Complications / Q000517:prevention & control*; D011247:Pregnancy; D011248:Pregnancy Complications; D018566:Pregnancy, High-Risk; D011300:Preoperative Care; D015742:Propofol; D013390:Succinylcholine; D013921:Thrombocytopenia / Q000150:complications; D020246:Venous Thrombosis / Q000209:etiology / Q000517:prevention & control
chemical_list: D013390:Succinylcholine; D009609:Nitrous Oxide; D015742:Propofol