[The effect of combining intra-aortic balloon pumping with tianma injection on myocardial ischemic-reperfusional injury in goats].
The objective of this study was to explore the effect of combined Intra-Aortic Balloon Pumping (I-ABP) and Tianma Injection on necrotic area in goat myocardial ischemic-reperfusional models which were established by two hours ischemia and a follow-up reperfusion. The results showed that the combined effect of IABP and Tianma Injection was more significant than that of IABP or Tianma separately. It is suggested that IABP and Tianma Injection have synergetic effect on the limitation of necrotic area, which possibly results from their mechanisms for decreasing the size of infarct.
Luo
H
H
Research Unit of Biomedical Engineering, West China University of Medical Sciences, Chengdu 610041.
Xiao
J
J
Liu
Q
Q
Wang
Z
Z
Li
S
S
Zhang
L
L
Xue
Z
Z
D000818:Animals; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006041:Goats; D007275:Injections, Intravenous; D007423:Intra-Aortic Balloon Pumping; D008297:Male; D015428:Myocardial Reperfusion Injury / Q000628:therapy*; D014665:Vasodilator Agents / Q000008:administration & dosage*
D004365:Drugs, Chinese Herbal; D014665:Vasodilator Agents