title: [Clinical significance of changes of interleukin 6 level in pregnancy induced hypertension].
abstract: OBJECTIVE
  To assess the clinical significance of changes of interleukin-6 (IL-6) level in patients with pregnancy induced hypertension (PIH).
  
  
  METHODS
  IL-6 level in urine and blood were measured by sandwich enzyme labeled immunosorbent assay (ELISA) in 82 patients with PIH and 30 normal pregnant women.
  
  
  RESULTS
  Blood IL-6 level in severe PIH patients was significantly higher than that in mild PIH patients and normal pregnant women. IL-6 level of urine in PIH patients were significantly higher than that in normal pregnant women and was associated with the severity of disease. There was a positive correlation between urinary IL-6 level and severity of renal damage in PIH.
  
  
  CONCLUSIONS
  Determination of IL-6 level is useful to understand the severity of PIH and its renal damage.
authors.affiliation: Traditional Chinese Medical Hospital of Linyi City, Shandong Linyi 276002.
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
authors.forename: H
authors.initials: H
authors.lastname: Song
authors.forename: S
authors.initials: S
authors.lastname: Shi
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood* / Q000652:urine; D011225:Pre-Eclampsia / Q000097:blood* / Q000652:urine; D011247:Pregnancy
chemical_list: D015850:Interleukin-6