title: Effects of leg rotation on lymph flow and pressure in rabbit lumbar lymph circulation: in vivo experiments and graphical analysis.
abstract: The intraluminal lymphatic pressure in rabbit lumbar lymphatic trunks was determined. To estimate the lymphatic pressure, graphical analysis was performed from lymph outflow pressure-flow rate relationship and lymph infusion pressure-flow rate relationship. A direct measurement technique with a T-tube was also carried out to measure the pressure in the lumbar lymphatic. The rabbit leg was passively rotated at 0.3 Hz in the diameter of 8 cm to enhance the lymphatic pump activity of the leg. The estimated pressure and measured pressure in the lymphatics were 6.50 and 7.14 +/- 2.38 cmH2O, respectively. It was confirmed that similar values could be obtained from these two methods. The lymphatic pumping in the leg may affect a distribution of pressure in the lumbar lymphatic system.
authors.affiliation: The 1st Department of Physiology, Shinshu University School of Medicine, Matsumoto, Japan. fikomi@sch.md.shinshu-u.ac.jp
authors.forename: F
authors.initials: F
authors.lastname: Ikomi
authors.forename: T
authors.initials: T
authors.lastname: Ohhashi
mesh_terms: D000818:Animals; D007866:Leg / Q000033:anatomy & histology / Q000502:physiology*; D008208:Lymphatic System / Q000502:physiology*; D008297:Male; D011312:Pressure; D011817:Rabbits; D012212:Rheology; D012399:Rotation; D013045:Species Specificity