title: Assessment of pseudohypertrophy as a measure of left-ventricular compression in patients with cardiac tamponade.
abstract: BACKGROUND
  Left-ventricular pseudohypertrophy reflecting left-ventricular compression was reported in a selected group of patients with cardiac tamponade.
  
  
  OBJECTIVE
  Criteria for the presence of pseudohypertrophy can be established to guide its use as a sign of left-ventricular compression in patients with cardiac tamponade.
  
  
  METHODS
  Left-ventricular wall thickness, diameters, relative diastolic wall thickness (%) = (posterior wall thickness/end diastolic radius) x 100 and estimated left-ventricular mass were measured in patients with small, moderate and large pericardial effusion, in patients with cardiac tamponade before and after pericardiocentesis (16 patients in each group) and in 30 control subjects with normal echocardiograms.
  
  
  RESULTS
  Left-ventricular posterior wall thickness was increased (12 +/- 2 vs. 9 +/- 1 mm, p < 0.001), left-ventricular end-diastolic diameter was reduced (3.9 +/- 0.5 vs. 4.6 +/- 0.3 cm, p < 0.001) and relative left-ventricular diastolic wall thickness was increased (61 +/- 13 vs. 41 +/- 4.5%, p < 0.001) only in patients with cardiac tamponade compared to controls, but not in patients with small, moderate and large effusions, respectively (relative wall thickness: 42 +/- 5, 41 +/- 7 and 44 +/- 7%, p = NS). Mean values of the estimated left-ventricular mass were similar in all groups. Following pericardiocentesis all parameters were normal.
  
  
  CONCLUSIONS
  Despite normal left-ventricular mass, relative left-ventricular diastolic wall thickness is elevated in patients with cardiac tamponade. In contrast it is normal in patients with various degrees of pericardial effusion supporting its use as a quantitative measure of left-ventricular compression in patients with suspected cardiac tamponade.
authors.affiliation: Heart Institute, Chaim Sheba Medical Center, Tel Hashomer, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. feinberg@netvision.net.il
authors.forename: M S
authors.initials: MS
authors.lastname: Feinberg
authors.forename: B A
authors.initials: BA
authors.lastname: Popescu
authors.forename: A C
authors.initials: AC
authors.lastname: Popescu
authors.forename: E
authors.initials: E
authors.lastname: Di Segni
authors.forename: M
authors.initials: M
authors.lastname: Jonas
authors.forename: B
authors.initials: B
authors.lastname: Rabinowitz
authors.forename: E
authors.initials: E
authors.lastname: Kaplinsky
authors.forename: E
authors.initials: E
authors.lastname: Schwammenthal
mesh_terms: D000328:Adult; D000368:Aged; D002305:Cardiac Tamponade / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D004452:Echocardiography / Q000379:methods; D005260:Female; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010490:Pericardial Effusion / Q000000981:diagnostic imaging / Q000503:physiopathology; D012680:Sensitivity and Specificity; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology*