title: Usefulness of magnetic resonance imaging for surgical management of extravasation of an antitumor agent: a case report.
abstract: We report a case of extravasation of an antitumor agent by preoperative magnetic resonance (MR) imaging. MR studies demonstrated a decreased signal intensity on T1- and T2-weighted images and a strong enhancement of contrast media in injured tissue, including subcutaneous adipose tissue and deep fascia, which was cicatrical macroscopically. The MR findings were in good agreement with the macroscopic findings. We believe that MR imaging is useful for estimating deep tissue damage due to extravasation of an antitumor agent.
authors.affiliation: Departments of Radiology, Sapporo Medical University, School of Medicine, Hokkaido, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Yama
authors.forename: Y
authors.initials: Y
authors.lastname: Tsuchida
authors.forename: S
authors.initials: S
authors.lastname: Nuka
authors.forename: S
authors.initials: S
authors.lastname: Kitagawa
authors.forename: J
authors.initials: J
authors.lastname: Saito
authors.forename: H
authors.initials: H
authors.lastname: Hyodoh
authors.forename: K
authors.initials: K
authors.lastname: Hyodoh
authors.forename: K
authors.initials: K
authors.lastname: Koito
authors.forename: M
authors.initials: M
authors.lastname: Tamakawa
authors.forename: H
authors.initials: H
authors.lastname: Akiba
authors.forename: M
authors.initials: M
authors.lastname: Hareyama
authors.forename: Y
authors.initials: Y
authors.lastname: Asai
mesh_terms: D000273:Adipose Tissue / Q000601:surgery; D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D003646:Debridement; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000175:diagnosis* / Q000601:surgery*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D016685:Mitomycin / Q000009:adverse effects*; D012004:Rectal Neoplasms / Q000188:drug therapy
chemical_list: D000903:Antibiotics, Antineoplastic; D016685:Mitomycin