PECAM-1 (CD31) engagement activates a phosphoinositide-independent, nonspecific cation channel in endothelial cells.
O'Brien
C D
CD
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. christoo@mail.med.upenn.edu
Ji
G
G
Wang
Y X
YX
Sun
J
J
Krymskaya
V P
VP
Ruberg
F L
FL
Kotlikoff
M I
MI
Albelda
S M
SM
D002118:Calcium / Q000378:metabolism; D020013:Calcium Signaling; D002412:Cations; D002478:Cells, Cultured; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D015640:Ion Channel Gating; D007473:Ion Channels / Q000378:metabolism*; D007700:Kinetics; D008954:Models, Biological; D018408:Patch-Clamp Techniques; D010716:Phosphatidylinositols / Q000378:metabolism; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D014162:Transfection
D002412:Cations; D007473:Ion Channels; D010716:Phosphatidylinositols; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D002118:Calcium