Hyperosmolar syndrome in a patient with uncontrolled diabetes mellitus.
Nonketotic hyperglycemic hyperosmolar syndrome (HHS) is found mostly in type 2 diabetic patients with marked hyperglycemia. HHS is a metabolic emergency and is associated with a high mortality rate. It is characterized by extreme dehydration and neurologic symptoms, which are related directly to the degree of hyperosmolality. We describe a 65-year-old patient who was admitted because of impaired consciousness caused by HHS. The relevant clinical and laboratory findings are discussed, and a brief overview of the pathophysiology and therapeutic management is provided.
Milionis
H J
HJ
Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece.
Liamis
G L
GL
Elisaf
M S
MS
D000368:Aged; D005260:Female; D006801:Humans; D006944:Hyperglycemic Hyperosmolar Nonketotic Coma / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy