title: DSM-IV and ICD-10 generalized anxiety disorder: discrepant diagnoses and associated disability.
abstract: BACKGROUND
  It is commonly assumed that diagnoses according to DSM-IV and ICD-10 are equivalent. Recent discussions on generalized anxiety disorder (GAD) have suggested that ICD-10 criteria may be identifying a milder form of the disorder than DSM-IV. This report examines prevalence and associated disability of DSM-IV and ICD-10 GAD.
  
  
  METHODS
  The Composite International Diagnostic Interview was administered to a community sample of 10,641 people, and the diagnostic criteria that contributed to discrepancies between DSM-IV and ICD-10 GAD were identified. A multiple linear regression analysis was carried out to determine the strength of the relationship between disability, as measured by the SF-12, and discrepant diagnoses of GAD.
  
  
  RESULTS
  The concordance between DSM-IV and ICD-10 GAD was fair (kappa = 0.39). The two sources of discrepancy when DSM-IV was positive and ICD-10 was negative resulted from the requirement in ICD-10 that the respondent endorse symptoms of autonomic arousal (ICD-10 criterion B) and the requirement that ICD-10 GAD does not co-occur with panic/agoraphobia, social phobia or obsessive-compulsive disorder (ICD-10 criterion C). The two major sources of discrepancy when ICD-10 was positive and DSM-IV was negative resulted from the requirement in DSM-IV that the worry be excessive (DSM-IV criterion A) and that it causes clinically significant distress or impairment (DSM-IV criterion E). DSM-only GAD cases had significantly higher levels of disability than ICD-only cases of GAD after controlling for demographic variables and the presence of comorbid psychiatric disorders.
  
  
  CONCLUSIONS
  While the prevalence rates for DSM-IV and ICD-10 GAD are almost identical, these classification systems are diagnosing different groups of people.
authors.affiliation: School of Psychiatry, University of New South Wales at St Vincent's Hospital, 299 Forbes Street, Darlinghurst, New South Wales, 2010 Australia. tims@crufad.unsw.edu.au
authors.forename: T
authors.initials: T
authors.lastname: Slade
authors.forename: G
authors.initials: G
authors.lastname: Andrews
mesh_terms: D000328:Adult; D000368:Aged; D001008:Anxiety Disorders / Q000145:classification* / Q000175:diagnosis* / Q000453:epidemiology; D001315:Australia / Q000453:epidemiology; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008370:Manuals as Topic; D008875:Middle Aged; D015995:Prevalence; D015203:Reproducibility of Results