Total and monounsaturated fat intake and serum estrogen concentrations in premenopausal Japanese women.
The relationships between fat intake and serum estrone, estradiol, and sex hormone-binding globulin were examined cross-sectionally in 60 premenopausal Japanese women. Blood samples were collected on Day 11 of the menstrual cycle. Intake of fats, classified according to fat type, and other macro- and micronutrients was estimated on the basis of daily diet records from Day 2 through Day 10 of the cycle. Total fat intake was significantly correlated with serum estrone concentration (Spearman r = 0.30, p = 0.02) and marginally significantly correlated with serum estradiol concentration (r = 0.26, p = 0.05) after controlling for age, total energy, and number of days before the next menses. Monounsaturated fat intake was significantly correlated with serum estrone (r = 0.32, p = 0.02) and serum estradiol (r = 0.27, p = 0.045). These data suggest an effect of dietary fat on serum estrogen concentrations.
Nagata
C
C
Department of Public Health, Gifu University School of Medicine, Gifu 500-8705, Japan.
Takatsuka
N
N
Kawakami
N
N
Shimizu
H
H
D000328:Adult; D003430:Cross-Sectional Studies; D015930:Diet Records; D004042:Dietary Fats, Unsaturated / Q000008:administration & dosage*; D004958:Estradiol / Q000097:blood; D004967:Estrogens / Q000097:blood*; D004970:Estrone / Q000097:blood; D005260:Female; D006801:Humans; D007564:Japan; D008598:Menstruation; D017697:Premenopause / Q000097:blood*; D012738:Sex Hormone-Binding Globulin / Q000032:analysis
D004042:Dietary Fats, Unsaturated; D004967:Estrogens; D012738:Sex Hormone-Binding Globulin; D004970:Estrone; D004958:Estradiol