title: Central retinal vein occlusion in a patient with thrombotic thrombocytopenic purpura.
abstract: OBJECTIVE
  To describe the occurrence of central retinal vein occlusion in a patient with thrombotic thrombocytopenic purpura.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  A 52-year-old woman developed central retinal vein occlusion in the acute phase of thrombotic thrombocytopenic purpura, followed by iris neovascularization only 1 month after the onset of central retinal vein occlusion. Color Doppler imaging of the affected eye showed an increased resistive index of the central retinal artery and reduced blood flow velocity of the central retinal vein compared to the fellow eye.
  
  
  CONCLUSIONS
  We describe a rare association between central retinal vein occlusion and thrombotic thrombocytopenic purpura with rapid evolution of iris neovascularization. Our case demonstrates that close ophthalmologic attention is important in thrombotic thrombocytopenic purpura.
authors.affiliation: Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Costa
authors.forename: M
authors.initials: M
authors.lastname: Krause
authors.forename: E
authors.initials: E
authors.lastname: Friedman
authors.forename: D J
authors.initials: DJ
authors.lastname: D'Amico
mesh_terms: D000208:Acute Disease; D001783:Blood Flow Velocity; D005260:Female; D006801:Humans; D007498:Iris / Q000098:blood supply; D017075:Laser Coagulation; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging / Q000209:etiology; D010956:Plasmapheresis; D011697:Purpura, Thrombotic Thrombocytopenic / Q000150:complications*; D015356:Retinal Artery Occlusion / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D018615:Ultrasonography, Doppler, Color; D014792:Visual Acuity