The characteristics of interaction between color and motion perception in primary open angle glaucoma.
OBJECTIVE
To investigate the characteristics of interaction between color and motion perception in primary open angle glaucoma (POAG) and measure motion perception of B, G and R cones, thus find a more sensitive method to diagnose the visual nerve damage in POAG.


METHODS
Motion perceptions of B, G and R cones were isolated by blue, green and red vertical line stimulus displayed on the yellow, purple and blue background respectively, then measured the displacement threshold and flicking threshold of motion perception from each cones in POAG, and compared it with the age-match normals.


RESULTS
The displacement threshold and flicking threshold of motion perception from B, G and R cones were all damaged in POAG compared with the normals, and the motion perception of G and B cones was deficits more obviously than the R cones.


CONCLUSIONS
These findings support the suggestion that color provides an input to human motion perception. Magnocellular and parvocellular pathway may be significantly damaged in POAG, which indicates, that the combination of Motion Perception and color testing may reveal preclinical visual nerve damage in early POAG.
Baowen
G
G
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.
De-zheng
W
W
Jongji
L
L
D000328:Adult; D000368:Aged; D003119:Color Perception Tests; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009039:Motion Perception; D020419:Photoreceptor Cells, Vertebrate / Q000502:physiology; D014795:Visual Pathways / Q000473:pathology