title: Regional reference values for some quantities measured with the ADVIA Centaur analyser. A model of co-operation between the in vitro diagnostic industry and clinical laboratories.
abstract: This work is a model of co-operation between the in vitro diagnostic industry and clinical laboratories for the production of reference values. Thirteen clinical laboratories having an ADVIA Centaur analyser and representing the majority of the geographical regions of Spain have shared the search for reference individuals and the production of reference values for thyrotropin, free thyroxine, free triiodothyronine, cobalamine and folate concentrations in serum. All the logistic work has been done in co-operation with the Spanish supplier of the ADVIA Centaur analyser. The reference limits produced in the virtual laboratory are derived from the blend of reference values obtained by each laboratory. The multicentre reference limits were estimated according to the recommendations of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC).
authors.affiliation: Servei de Bioquimica Clinica, Ciutat Sanitària i Universitària de Bellvitge, L'Hospitalet de Llobregat, Catalonia, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Ferré-Masferrer
authors.forename: X
authors.initials: X
authors.lastname: Fuentes-Arderiu
authors.forename: M
authors.initials: M
authors.lastname: Gomà-Llongueras
authors.forename: A
authors.initials: A
authors.lastname: Alumà-Trullàs
authors.forename: M
authors.initials: M
authors.lastname: Aramendi-Ramos
authors.forename: J L
authors.initials: JL
authors.lastname: Castaño-Vidriales
authors.forename: M
authors.initials: M
authors.lastname: Esteban-Salan
authors.forename: M
authors.initials: M
authors.lastname: Graells-Ferrer
authors.forename: A
authors.initials: A
authors.lastname: Jiménez-González
authors.forename: C
authors.initials: C
authors.lastname: Jiménez-Lobo
authors.forename: M
authors.initials: M
authors.lastname: López-Esparza
authors.forename: L
authors.initials: L
authors.lastname: Parés-Pollán
authors.forename: M
authors.initials: M
authors.lastname: Regulez-Uranga
authors.forename: M
authors.initials: M
authors.lastname: Riesco-Prieto
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez-Camba
authors.forename: J
authors.initials: J
authors.lastname: Vidal-Martínez
mesh_terms: D000328:Adult; D001774:Blood Chemical Analysis / Q000295:instrumentation* / Q000592:standards*; D005260:Female; D005492:Folic Acid / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D013030:Spain; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood; D014805:Vitamin B 12 / Q000097:blood
chemical_list: D014284:Triiodothyronine; D013972:Thyrotropin; D005492:Folic Acid; D014805:Vitamin B 12; D013974:Thyroxine