[Study of relation between ureaplasma urealyticum and fetal intrauterine growth retardation].
OBJECTIVE
To study the influences of Ureaplasma Urealyticum (UU) infection to fetal intrauterine growth.


METHODS
Polymerase Chain Reaction was used to detect UU in samples of cervical secretions, umbilical blood and placenta. The study group included 50 women with neonatal birth weight below 2,500 g, 50 women with newborns birth weight above 2,500 g served as control group.


RESULTS
Positive rate of UU in samples of cord blood and placenta and placental chorioamnionitis in study group were higher than that in the control group (P < 0.005 and P < 0.05). There was no significant difference of UU positive rate in cervical samples between two groups. The positive rate of UU in cases with chorioamnionitis was higher than that of cases with negative UU infection (P < 0.05).


CONCLUSIONS
UU may interfere fetal intrauterine growth through infecting umbilical blood and placenta.
Zhou
H
H
Nanjing Railway Medical College, Nanjing 210009.
Li
M
M
Cheng
Y
Y
D000328:Adult; D005260:Female; D005312:Fetal Blood / Q000382:microbiology; D005317:Fetal Growth Retardation / Q000382:microbiology*; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D018445:Infectious Disease Transmission, Vertical; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011897:Random Allocation; D016869:Ureaplasma Infections / Q000635:transmission*; D016990:Ureaplasma urealyticum