title: Quality of life and factors related to perceived satisfaction with quality of life after allogeneic bone marrow transplantation.
abstract: The quality of life after bone marrow transplantation (BMT) was studied in 109 adult allogeneic BMT recipients transplanted on at the Helsinki University Central hospital for a haematological malignancy. Physical, functional, emotional and social well-being was measured on the Functional Assessment of Cancer Therapy Scale (FACT-BMT) and a shortened version of the Profile of Mood States Scale (POMS) and by the MOS social support survey and a Brief Measure of Social Support (SSQ6). The results of the present study replicate those of previous investigations by finding that physical well-being, educational level, age at BMT and social support have an impact on the perceived quality of life of BMT patients. Our results indicate that these factors have a varying impact at different time points during the post-BMT recovery process. During the first three years after BMT, physical well-being proved to be a highly significant (P < 0.001) factor for perceived life satisfaction. Moreover, physical well-being showed an average significant improvement after the first post-BMT year. The percentage of the recipients experiencing the highest levels of satisfaction with life increased from 51% during the first year after BMT to 81% for those patients five years post-BMT. One year after BMT, 75.6% of the BMT recipients were able to work, 67.8% of the patients were actively participating in work/school and 7.8% were unemployed.
authors.affiliation: Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland. heikki.heinonen@ktl.fi
authors.forename: H
authors.initials: H
authors.lastname: Heinonen
authors.forename: L
authors.initials: L
authors.lastname: Volin
authors.forename: A
authors.initials: A
authors.lastname: Uutela
authors.forename: M
authors.initials: M
authors.lastname: Zevon
authors.forename: C
authors.initials: C
authors.lastname: Barrick
authors.forename: T
authors.initials: T
authors.lastname: Ruutu
mesh_terms: D000328:Adult; D001294:Attitude to Health; D016026:Bone Marrow Transplantation / Q000523:psychology; D005260:Female; D019337:Hematologic Neoplasms / Q000523:psychology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011581:Psychological Tests; D011788:Quality of Life; D018434:Sickness Impact Profile; D012944:Social Support; D014184:Transplantation, Homologous