Molecular targets for breast cancer therapy and prevention.
The recent completion of the human genome sequence has raised great hopes for the discovery of new breast cancer therapies based on newly-discovered genes linked to breast cancer development and progression. Here we describe breast cancer therapies that have emerged from gene-based scientific efforts over the past 20 years and that are now approved for clinical testing or treatment.
Bange
J
J
Max-Planck-Institut of Biochemistry, Department of Molecular Biology Martinsried, Germany.
Zwick
E
E
Ullrich
A
A
D020533:Angiogenesis Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000098:blood supply / Q000188:drug therapy / Q000235:genetics* / Q000517:prevention & control; D005260:Female; D018734:Genes, erbB-2; D006801:Humans; D009389:Neovascularization, Pathologic / Q000517:prevention & control
D020533:Angiogenesis Inhibitors