title: Immediate breast reconstruction with saline-filled implants: no interference with the oncologic outcome?
abstract: The possible adverse effects on cancer control due to immediate breast reconstruction have been addressed recently for both silicone-filled implants and flap reconstruction. To evaluate those possible effects after immediate breast reconstruction with saline-filled implants, 49 patients reconstructed with saline-filled breast implants at the Jules Bordet Cancer Institute were studied. Selection was only based on the possibility to find a matched patient. These patients were matched with a control group of 49 matched women with breast cancer treated in the same center by mastectomy without any type of breast reconstruction. The two groups were comparable according to age at diagnosis (within 3 years), year of diagnosis (same year), stage of the tumor, histology, and nodal status. The only difference between the two groups was that radiation therapy was applied to some of the patients who were not reconstructed (due to tumor location). The results show, in terms of local recurrences, distant metastasis, and deaths, no significant difference between the two groups, even for the irradiated patients, within a mean follow-up period of 72 months (range, 24 to 108) months.
authors.affiliation: Plastic and Reconstructive Surgery, Department and the Breast Diseases Surgery Department at Jules Bordet Institute for Cancer, Brussels, Belgium. vandeweyere@skynet.be
authors.forename: E
authors.initials: E
authors.lastname: Vandeweyer
authors.forename: D
authors.initials: D
authors.lastname: Hertens
authors.forename: J M
authors.initials: JM
authors.lastname: Nogaret
authors.forename: R
authors.initials: R
authors.lastname: Deraemaecker
mesh_terms: D000328:Adult; D000368:Aged; D019928:Breast Implantation; D018427:Breast Implants; D001943:Breast Neoplasms / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000601:surgery*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013997:Time Factors; D016896:Treatment Outcome