title: Celiac vagotomy reduces suppression of feeding by jejunal fatty acid infusions.
abstract: We investigated the role of the celiac branch of the vagus nerve in suppression of food intake produced by jejunal fatty acids infusions. Following selective celiac vagotomy or sham surgery, adult, male Sprague-Dawley rats received 7 h infusions of linoleic acid or saline through indwelling jejunal catheters on four consecutive days. Although linoleic acid still produced significant suppression of intake in rats with celiac vagotomy, it was less effective in these animals than in controls. The temporal pattern of results suggested that celiac afferent fibers are involved in mediating both pre- and postabsorptive effects of infused fatty acids.
authors.affiliation: Department of Psychology, Campbell Hall, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Cox
authors.forename: W J
authors.initials: WJ
authors.lastname: Tyler
authors.forename: A
authors.initials: A
authors.lastname: Randich
authors.forename: G R
authors.initials: GR
authors.lastname: Kelm
authors.forename: S T
authors.initials: ST
authors.lastname: Meller
mesh_terms: D000344:Afferent Pathways / Q000187:drug effects / Q000502:physiology; D000818:Animals; D005247:Feeding Behavior / Q000187:drug effects* / Q000502:physiology; D005728:Ganglia, Sympathetic / Q000187:drug effects* / Q000502:physiology* / Q000601:surgery; D007583:Jejunum / Q000187:drug effects* / Q000502:physiology; D019787:Linoleic Acid / Q000494:pharmacology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D014628:Vagotomy / Q000379:methods
chemical_list: D019787:Linoleic Acid