[Malignant central nervous system tumors are susceptible to specific antibodies].
The binding of circulating specific IgG to glioblastoma cells from brain tumor biopsies was shown using fluorescence conjugate Protein A-FITC and Western blotting. Blood-brain barrier permeability for antitumor antibodies in vivo in glioblastoma patients is suggested.
Blizniukov
O P
OP
St. Petersburg Institute of Nuclear Physics, Russian Academy of Sciences, Gatchina.
Kozmin
L D
LD
Oliushin
V E
VE
Ostreĭko
O V
OV
Filatov
M V
MV
D000912:Antibodies, Neoplasm / Q000627:therapeutic use*; D015153:Blotting, Western; D001932:Brain Neoplasms / Q000276:immunology* / Q000628:therapy*; D016650:Fluorescein-5-isothiocyanate; D005910:Glioma / Q000276:immunology* / Q000628:therapy*; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use*; D016896:Treatment Outcome
D000912:Antibodies, Neoplasm; D007074:Immunoglobulin G; D016650:Fluorescein-5-isothiocyanate