title: Multiple eccrine hidrocystomas of the face.
abstract: BACKGROUND
  Multiple eccrine hidrocystomas of the face are a rare facial dermatosis for which no recent large series of cases has been reported.
  
  
  OBJECTIVE
  To describe the clinicopathologic features of five cases of multiple eccrine hidrocystoma and to emphasize their similar characteristics.
  
  
  METHODS
  The clinical and histologic features of five women with multiple eccrine hidrocystomas of the face are described.
  
  
  RESULTS
  All cases were middle-aged women with numerous, asymptomatic, skin-colored to bluish, papulonodular skin lesions, ranging from 2 to 5 mm in diameter, and mainly centrifacial in distribution. Histopathologically, all cases showed unilocular cysts in the dermis lined by two layers of cuboidal cells. Staining for S-100 protein was negative in the cyst wall in all cases. One case was treated with topical 1% atropine for 3 weeks with no significant improvement. No systemic side-effects were observed during this treatment.
  
  
  CONCLUSIONS
  Multiple eccrine hidrocystomas are a rare condition which might be confused clinically and histopathologically with apocrine hidrocystomas. To date, no effective treatment has been reported.
authors.affiliation: Departments of Medicine and Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
authors.forename: A
authors.initials: A
authors.lastname: Alfadley
authors.forename: K
authors.initials: K
authors.lastname: Al Aboud
authors.forename: A
authors.initials: A
authors.lastname: Tulba
authors.forename: M M
authors.initials: MM
authors.lastname: Mourad
mesh_terms: D000328:Adult; D000368:Aged; D001050:Apocrine Glands / Q000473:pathology; D001706:Biopsy; D004439:Eccrine Glands / Q000473:pathology*; D005145:Face / Q000473:pathology*; D005260:Female; D018251:Hidrocystoma / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D013544:Sweat Gland Neoplasms / Q000473:pathology*