title: Episodic hyperlibidinism in multiple sclerosis.
abstract: BACKGROUND
  Changes in sexual function are commonly associated with MS and occur in many forms. Hypersexual thoughts or behavior are rare, but can present on the background of persistent cognitive impairment or psychiatric conditions such as mania, whereas isolated hypersexuality is still rarer.
  
  
  METHODS
  We describe the clinical, neuropsychological, electrodiagnostic, neuroimaging and endocrine findings in a MS patient with episodes of greatly increased libido. Imaging and neuropsychologicol studies indicated frontal lobe dysfunction; hormone studies showed no significant changes.
  
  
  CONCLUSIONS
  Episodic hypersexuality can be a recurrent transient manifestation of MS.
authors.affiliation: St. Louis Veterans Administration Hospital, Saint Louis University School of Medicine, Missouri, USA.
authors.forename: F A
authors.initials: FA
authors.lastname: Gondim
authors.forename: F P
authors.initials: FP
authors.lastname: Thomas
mesh_terms: D001327:Autoimmune Diseases / Q000473:pathology / Q000503:physiopathology / Q000523:psychology*; D004569:Electroencephalography; D005260:Female; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D007989:Libido; D008279:Magnetic Resonance Imaging; D008418:Masturbation; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000473:pathology / Q000503:physiopathology / Q000523:psychology*; D009483:Neuropsychological Tests; D020018:Sexual Dysfunctions, Psychological / Q000097:blood / Q000209:etiology* / Q000473:pathology
chemical_list: D012739:Gonadal Steroid Hormones