title: Sildenafil: a urologist's view.
abstract: Erectile dysfunction (ED) is a common problem with a multifactorial aetiology. The treatment of ED has been revolutionised by the introduction of intracavernosal injections some two decades ago. However, the recent development of the orally-administered drug sildenafil (Viagra) has had a major impact on the treatment of ED. We discuss the trials with sildenafil with special reference to cardiovascular risk factors associated with ED.
authors.affiliation: Department of Urology, Royal Free and University College Medical School (University College London), Royal Free Campus and Royal Free Hampstead NHS Trust, London, UK.
authors.forename: M A
authors.initials: MA
authors.lastname: Khan
authors.forename: D P
authors.initials: DP
authors.lastname: Mikhailidis
authors.forename: R J
authors.initials: RJ
authors.lastname: Morgan
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000150:complications; D048909:Diabetes Complications; D007172:Erectile Dysfunction / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use*; D010879:Piperazines / Q000627:therapeutic use*; D011687:Purines; D000068677:Sildenafil Citrate; D012907:Smoking; D013450:Sulfones
chemical_list: D010726:Phosphodiesterase Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate