Congenital vascular lesions of the gastrointestinal tract: blue rubber bleb nevus and Klippel-Trenaunay syndromes.
We present two cases of hemangiomatosis of the gastrointestinal tract. The first case describes a 59-year-old patient with upper gastrointestinal hemorrhage due to the blue rubber bleb nevus syndrome. The second case illustrates a 26-year-old patient with recurrent rectal bleeding due to Klippel-Trenaunay syndrome. These two syndromes are distinct disorders characterized by cavernous hemangiomas of the skin, soft-tissue, bones, and viscera. In addition, we review the available literature on the epidemiology, transmission, clinical features, associated conditions, diagnosis, and treatment of these two disorders.
Arguedas
M R
MR
Department of Medicine, University of Alabama at Birmingham, 35297-0007, USA.
Shore
G
G
Wilcox
C M
CM
D000328:Adult; D016145:Endoscopy, Digestive System; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D005770:Gastrointestinal Neoplasms / Q000151:congenital* / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D005799:Genes, Dominant; D018324:Hemangioma, Capillary / Q000151:congenital* / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D006801:Humans; D007715:Klippel-Trenaunay-Weber Syndrome / Q000151:congenital* / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D008297:Male; D008875:Middle Aged; D018329:Nevus, Blue / Q000151:congenital* / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D012008:Recurrence; D015911:Sclerotherapy / Q000379:methods; D013577:Syndrome; D014057:Tomography, X-Ray Computed