title: Comparison of the efficacy of different doses of Ukrain in the combined treatment of breast cancer.
abstract: The aim of this study was to compare the efficacy of different Ukrain doses in the combined treatment of 75 patients with breast cancer. The patients were divided into three groups: groups I and II (25 patients each) were treated with 50 mg and 100 mg of Ukrain, respectively, before surgery; group III (25 patients) served as control (without Ukrain treatment). Clinical observations, biochemical, hormonal and immunologic indices indicated that both doses of Ukrain had a similar beneficial effect on patient outcome and may be indicated in the presurgical treatment of patients with breast cancer.
authors.affiliation: Grodno Medical University, Grodno, Belarus.
authors.forename: K N
authors.initials: KN
authors.lastname: Uglyanitsa
authors.forename: L I
authors.initials: LI
authors.lastname: Nefyodov
authors.forename: Y M
authors.initials: YM
authors.lastname: Doroshenko
authors.forename: W J
authors.initials: WJ
authors.lastname: Brzosko
mesh_terms: D000368:Aged; D000470:Alkaloids / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001600:Berberine Alkaloids; D001777:Blood Coagulation / Q000187:drug effects; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D018655:Lymphocyte Count; D008408:Mastectomy; D008875:Middle Aged; D010617:Phenanthridines; D016896:Treatment Outcome
chemical_list: D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D001600:Berberine Alkaloids; D010617:Phenanthridines; C060921:ukrain