title: Induction of HIF-1alpha in response to hypoxia is instantaneous.
authors.affiliation: Institute of Physiology, University of Zürich, CH-8057 Zürich, Switzerland.
authors.forename: U R
authors.initials: UR
authors.lastname: Jewell
authors.forename: I
authors.initials: I
authors.lastname: Kvietikova
authors.forename: A
authors.initials: A
authors.lastname: Scheid
authors.forename: C
authors.initials: C
authors.lastname: Bauer
authors.forename: R H
authors.initials: RH
authors.lastname: Wenger
authors.forename: M
authors.initials: M
authors.lastname: Gassmann
mesh_terms: D019757:Carbon-Oxygen Lyases / Q000378:metabolism; D015687:Cell Hypoxia / Q000502:physiology*; D043603:DNA-(Apurinic or Apyrimidinic Site) Lyase; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D005786:Gene Expression Regulation; D006367:HeLa Cells; D006801:Humans; D051793:Hypoxia-Inducible Factor 1; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D015151:Immunoblotting; D007700:Kinetics; D016328:NF-kappa B / Q000378:metabolism; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism; D016755:Proto-Oncogene Proteins c-jun / Q000378:metabolism; D013879:Thioredoxins / Q000378:metabolism; D013997:Time Factors; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D004268:DNA-Binding Proteins; C497442:HIF1A protein, human; D051793:Hypoxia-Inducible Factor 1; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D016328:NF-kappa B; D009687:Nuclear Proteins; D016760:Proto-Oncogene Proteins c-fos; D016755:Proto-Oncogene Proteins c-jun; D014157:Transcription Factors; D013879:Thioredoxins; D019757:Carbon-Oxygen Lyases; C085108:APEX1 protein, human; D043603:DNA-(Apurinic or Apyrimidinic Site) Lyase; D010100:Oxygen