title: Laparoscopic nephrectomy in young-old, old-old, and oldest-old adults.
abstract: BACKGROUND
  This study reports findings for laparoscopic nephrectomy in comparison with open nephrectomy in geriatric patients.
  
  
  METHODS
  Since 1993, a total of 249 patients have undergone nephrectomy for benign disease at the Medical University of Lübeck, Germany. In 11 patients older than 65 years, a laparoscopic nephrectomy was performed (in the majority via a transperitoneal approach), and 42 patients older than 65 years underwent an open-flank nephrectomy. Clinical parameters were evaluated in comparison with both groups and stratified according to age groups.
  
  
  RESULTS
  With respect to operative results (operative duration and pre- and postoperative hemoglobin levels), no relevant differences were observed between the laparoscopy group and the open-nephrectomy group, even when stratified according to patient age. However, patients in the laparoscopy group demonstrated a significant advantage concerning blood loss and the number of required blood transfusions, regardless of age. In addition, patients after laparoscopy showed advantages in the postoperative course. Benefits were proven for the analgesic consumption, hospital stay, and convalescence parameters. Although complication rates were comparable in both groups, an increase was observed in both groups for patients aged between 75 and 84 years.
  
  
  CONCLUSIONS
  Laparoscopic nephrectomy offers comparable operative results (with reduced blood loss and less need for blood transfusions) when compared with open surgery. Significant advantages can be demonstrated in the postoperative course, and especially geriatric patients benefit from these aspects of the minimally invasive approach. Laparoscopy should be regarded as the primary therapeutic option for nephrectomy for benign disease in these patients.
authors.affiliation: Department of Urology, Medical University of Lübeck, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Fornara
authors.forename: C
authors.initials: C
authors.lastname: Doehn
authors.forename: R
authors.initials: R
authors.lastname: Frese
authors.forename: D
authors.initials: D
authors.lastname: Jocham
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D009392:Nephrectomy / Q000379:methods*; D016896:Treatment Outcome