Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization.
Koushik
S V
SV
Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia 30912-2640, USA.
Wang
J
J
Rogers
R
R
Moskophidis
D
D
Lambert
N A
NA
Creazzo
T L
TL
Conway
S J
SJ
D000818:Animals; D002118:Calcium / Q000378:metabolism; D005314:Embryonic and Fetal Development; D018390:Gene Targeting; D017930:Genes, Reporter; D006321:Heart / Q000033:anatomy & histology / Q000196:embryology* / Q000502:physiology*; D007150:Immunohistochemistry; D051379:Mice; D008822:Mice, Transgenic; D009024:Morphogenesis; D009200:Myocardial Contraction / Q000502:physiology*; D009206:Myocardium / Q000378:metabolism / Q000648:ultrastructure; D019831:Sodium-Calcium Exchanger / Q000235:genetics / Q000378:metabolism*
D019831:Sodium-Calcium Exchanger; C110374:sodium-calcium exchanger 1; D002118:Calcium