title: [Efficacy of topical povidone-iodine applied the day before cataract surgery to reduce conjunctival flora].
abstract: OBJECTIVE
  To evaluate the efficacy of the topical use of periocular and conjunctival povidone-iodine solution applied the day before cataract surgery to reduce conjunctival flora.
  
  
  METHODS
  Randomized and prospective clinical trial with 82 patients. The treatment group (41 patients) received an application of topical 10% povidone-iodine solution on the periocular skin and instillation of topical 5% povidone-iodine solution on the forniceal conjunctiva the day before and one hour before surgery. The control group (41 patients) only received the usual perioperative disinfectant. Conjunctival smears were obtained from in all patients at the end of the surgery and these were sent to the Microbiology Laboratory for culture.
  
  
  RESULTS
  In the treatment group 1 positive culture was found in the 41 eyes (2.4%). In the control group, there were positive cultures in 6 out of 41 eyes (14.6%). The difference is statistically significant (p<0.05).
  
  
  CONCLUSIONS
  The disinfecting of the periocular skin with 10% povidone-iodine solution and of the conjunctiva with 5% povidone-iodine solution the day before and one hour before cataract surgery is effective in reducing conjunctival bacterial colonization compared with perioperative disinfection alone.
authors.affiliation: Servicio de Oftalmología, Hospital General del INSALUD de Albacete, España.
authors.forename: C
authors.initials: C
authors.lastname: González Bandrés
authors.forename: M J
authors.initials: MJ
authors.lastname: Carrilero Ferrer
authors.forename: L
authors.initials: L
authors.lastname: Buznego Suárez
authors.forename: M A
authors.initials: MA
authors.lastname: García Claramunt
authors.forename: M
authors.initials: M
authors.lastname: Méndez Llata
authors.forename: B
authors.initials: B
authors.lastname: Paredes
authors.forename: M
authors.initials: M
authors.lastname: Moriche Carretero
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use*; D002387:Cataract Extraction; D003228:Conjunctiva / Q000382:microbiology*; D004334:Drug Administration Schedule; D015818:Eye Infections, Bacterial / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011206:Povidone-Iodine / Q000008:administration & dosage / Q000627:therapeutic use*; D011292:Premedication; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine