title: Is uranyl scavenger hexakis(3,6-anhydro) tetrakis(2A,B,D,E-O-octyl) cyclomaltohexaose (OCT) relevant with biosystems?
abstract: Hexakis(3,6-anhydro)tetrakis(2A,B,D,E-O-octyl) cyclomatohexaose (OCT) has been recently shown as a powerful cryptant for lead, mercury, and especially for uranyl. As previous results have been obtained in an organic solvent (methanol), a similar evaluation of OCT complex formation was achieved in aqueous medium and in the presence of membrane-mimicking systems such as phospholipid vesicles, liposomes and micelles. It was found that OCT, while completely insoluble in water, forms solid gel structures when in equimolar mixtures of water and methanol. Moreover, OCT exhibits detergent properties. Finally, OCT was successfully introduced in detergent solutions while keeping. Uranyl complexing properties. Possible applications of such models were also discussed.
authors.affiliation: CRSSA/BCM, La Tronche, France.
authors.forename: J C
authors.initials: JC
authors.lastname: Debouzy
authors.forename: A
authors.initials: A
authors.lastname: Gadelle
authors.forename: F
authors.initials: F
authors.lastname: Fauvelle
authors.forename: S
authors.initials: S
authors.lastname: Aous
authors.forename: J Y
authors.initials: JY
authors.lastname: Pailler
authors.forename: E
authors.initials: E
authors.lastname: Gentilhomme
authors.forename: P
authors.initials: P
authors.lastname: Perrin
authors.forename: F
authors.initials: F
authors.lastname: Lhoste
mesh_terms: D002614:Chelating Agents / Q000737:chemistry*; D003505:Cyclodextrins / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008823:Micelles; D012996:Solutions; D012997:Solvents; D014501:Uranium / Q000737:chemistry*; D047408:gamma-Cyclodextrins
chemical_list: D002614:Chelating Agents; D003505:Cyclodextrins; D008823:Micelles; D012996:Solutions; D012997:Solvents; D047408:gamma-Cyclodextrins; C429903:hexakis(3,6-anhydro)tetrakis(2A,B,D,E-O-octyl)cyclomaltohexaose; D014501:Uranium