Quantitative structure-activity relationships: comparative inhibition of nitrogen-containing aromatics on germination of Cucumis sativus.
Comparative inhibition effect of selected nitrogen-containing aromatics on germination rate of Cucumis sativus was investigated, and quantitative structure-activity relationships were developed and mechanistically interpreted. Energy of lowest unoccupied orbital was found to successfully model the toxicity of the test chemicals. It was discovered that inhibition of nitrogen-containing aromatics to germination of Cucumis sativus was caused mainly by their in vivo redox reaction.
Wang
X
X
Department of Environmental Science & Engineering, Nanjing University, People's Republic of China.
Sun
C
C
Wang
L
L
Han
S
S
D000631:Aminopyridines / Q000633:toxicity*; D000814:Aniline Compounds / Q000633:toxicity*; D018553:Cucumis sativus / Q000187:drug effects / Q000502:physiology*; D007700:Kinetics; D009596:Nitrophenols / Q000633:toxicity*; D010084:Oxidation-Reduction; D021281:Quantitative Structure-Activity Relationship; D012639:Seeds / Q000187:drug effects*
D000631:Aminopyridines; D000814:Aniline Compounds; D009596:Nitrophenols