Iron status and indicators of human immunodeficiency virus disease severity among pregnant women in Malawi.
The relationships among hemoglobin, ferritin, and transferrin receptor levels and 2 markers of human immunodeficiency virus (HIV) disease severity--HIV load and CD4(+) lymphocyte count--were characterized among 483 pregnant women in Malawi, Africa. The only significant correlation was an inverse correlation between hemoglobin level and plasma HIV load (r=-.104; P<.03). The prevalence of iron deficiency anemia was not significantly different across quartiles of HIV load or CD4(+) lymphocyte count. In contrast to previous studies, these data suggest that iron status is not related to markers of HIV disease severity in pregnant women in Africa.
Semba
R D
RD
Department of Ophthalmology, Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, MD 21205, USA. rdsemba@jhmi.edu
Taha
T E
TE
Kumwenda
N
N
Mtimavalye
L
L
Broadhead
R
R
Miotti
P G
PG
Chiphangwi
J D
JD
D018798:Anemia, Iron-Deficiency / Q000175:diagnosis*; D018791:CD4 Lymphocyte Count; D018450:Disease Progression; D005260:Female; D006678:HIV / Q000502:physiology; D015658:HIV Infections / Q000097:blood / Q000503:physiopathology* / Q000821:virology; D006801:Humans; D007501:Iron / Q000097:blood*; D008295:Malawi; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood / Q000503:physiopathology* / Q000821:virology; D012720:Severity of Illness Index; D019562:Viral Load
D007501:Iron