Ab initio protein structure prediction: progress and prospects.
Considerable recent progress has been made in the field of ab initio protein structure prediction, as witnessed by the third Critical Assessment of Structure Prediction (CASP3). In spite of this progress, much work remains, for the field has yet to produce consistently reliable ab initio structure prediction protocols. In this work, we review the features of current ab initio protocols in an attempt to highlight the foundations of recent progress in the field and suggest promising directions for future work.
Bonneau
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Department of Biochemistry, University of Washington, Seattle, Washington, Box 357350, 98195, USA. dabaker@u.washington.edu
Baker
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D
D000465:Algorithms; D016678:Genome; D008962:Models, Theoretical; D011487:Protein Conformation; D017510:Protein Folding; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry*; D012984:Software
D011506:Proteins