Dosimetry of blood irradiation using an alanine/ESR dosimeter.
A batch of 80 DL-alanine dosimeters was supplied to Hemocentro of the Hospital and Clinics of Faculdade de Medicina de Ribeirão Preto (HC-FM RP) SP, Brazil for the purpose of quality control of the radiation dose delivered to blood bags. The irradiation was made using two (40 x 40) cm2 parallel opposed radiation fields each with 80 cm of source to surface distance in the Radiotherapy Section of HC-FMRP with the 60Co teletherapy unit. The calculated radiation absorbed dose at the center of the box was 20 Gy. The dosimeter readings were performed using a Varian E-4 ESR Spectrometer operating in X-band. For the 80 dosimeters and over the irradiation volume throughout a blood bag, the minimum and maximum doses were 14 and 23 Gy, respectively. The mean dose was (18 +/- 2) Gy (1sigma), and the coefficient of variability was 11.1%. Alanine dosimeters demonstrated easy handling, good precision and adequate sensitivity for this application.
Chen
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Departamento de Fisica e Matematica, FFCLRP, Universidade de São Paulo Ribeirão Preto, Brazil.
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Baffa
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D000409:Alanine / Q000528:radiation effects; D001769:Blood / Q000528:radiation effects*; D001938:Brazil; D004307:Dose-Response Relationship, Radiation; D004578:Electron Spin Resonance Spectroscopy; D006801:Humans; D011786:Quality Control; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods* / Q000592:standards
D000409:Alanine