Misuse of corticosteroids in some of the drugs dispensed as preparations from alternative systems of medicine in India.
Screening for corticosteroids carried out on 120 samples of alternative medicines which were dispensed to patients suffering mainly from asthma, arthritis, etc., showed that 38.32% of them were adulterated with steroids. Most of these samples were submitted for screening by either a medical practitioner or the patients themselves, who suspected effects of steroids from these drugs. The percentage of steroid positivity was determined in ayurvedic drugs, homeopathic drugs, and unknown or other category of drugs. The presence of steroids in these drugs given for different ailments such as asthma, arthritis, and unknown/other ailments was also tabulated. The results show that a high percentage of these samples contained corticosteroids, however, the distribution of positivity amongst groups was not statistically significant. The lack of proper quality control mechanisms to verify ingredients or efficacy of 'alternative medicines' has led to the proliferation of the practice of dispensing spurious drugs containing corticosteroids as alternative medicines. This study aims to highlight the existence of 'quick fix' remedies dispensed as 'alternative medicines' which not only cause extensive adverse health effects to the patients but also bring alternative systems of medicines into disrepute. The deliberate contamination of corticosteroids with alternative systems of medicine by some practitioners is a cause of great concern. Such practices may not only disgrace alternative systems of medicine but may also lead to adverse side-effects on chronic exposure.
Gupta
S K
SK
Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India. skgupta@medinst.ernet.in
Kaleekal
T
T
Joshi
S
S
D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000032:analysis*; D001168:Arthritis / Q000188:drug therapy; D001249:Asthma / Q000188:drug therapy; D004340:Drug Contamination / Q000706:statistics & numerical data*; D006801:Humans; D007194:India; D008419:Materia Medica / Q000032:analysis*; D008515:Medicine, Ayurvedic; D017891:Pharmacoepidemiology
D000305:Adrenal Cortex Hormones; D008419:Materia Medica