title: Treatment of sepsis in the small tarsal joints of 11 horses with gentamicin-impregnated polymethylmethacrylate beads.
abstract: Gentamicin-impregnated polymethylmethacrylate beads were used to treat infective arthritis in the small tarsal joints of 11 severely lame horses. Under general anaesthesia, between five and 10 beads were placed into a 7 to 8 mm tract drilled across the affected joint and, in all except one horse, they were left in place for 14 days. Two of the horses were euthanased for reasons other than persistent tarsal joint sepsis, but the other nine survived and seven of them returned to their previous level of athletic performance.
authors.affiliation: Department of Veterinary Clinical Sciences and Animal Husbandry, Large Animal Veterinary Teaching Hospital, University of Liverpool, Leahurst.
authors.forename: T M
authors.initials: TM
authors.lastname: Booth
authors.forename: R J
authors.initials: RJ
authors.lastname: Butson
authors.forename: P D
authors.initials: PD
authors.lastname: Clegg
authors.forename: M C
authors.initials: MC
authors.lastname: Schramme
authors.forename: R K
authors.initials: RK
authors.lastname: Smith
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D016503:Drug Delivery Systems / Q000662:veterinary; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage*; D006734:Horse Diseases / Q000188:drug therapy* / Q000382:microbiology; D006736:Horses; D007794:Lameness, Animal; D008297:Male; D008863:Microspheres; D019904:Polymethyl Methacrylate; D011859:Radiography; D018805:Sepsis / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D013640:Tarsal Joints / Q000000981:diagnostic imaging / Q000382:microbiology*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins; D019904:Polymethyl Methacrylate