Cell control by membrane-cytoskeleton adhesion.
The rates of mechanochemical processes, such as endocytosis, membrane extension and membrane resealing after cell wounding, are known to be controlled biochemically, through interaction with regulatory proteins. Here, I propose that these rates are also controlled physically, through an apparently continuous adhesion between plasma membrane lipids and cytoskeletal proteins.
Sheetz
M P
MP
Department of Biological Sciences, PO Box 2408, Columbia University, Sherman Fairchild Center, 1212 Amsterdam Avenue, New York, NY 10027, USA. ms2001@columbia.edu
D002448:Cell Adhesion / Q000502:physiology; D002462:Cell Membrane / Q000737:chemistry* / Q000502:physiology*; D003599:Cytoskeleton / Q000502:physiology*; D004705:Endocytosis / Q000502:physiology; D005057:Eukaryotic Cells / Q000166:cytology*; D008954:Models, Biological