title: Acute cholestatic hepatitis caused by a probable allergic reaction to paracetamol in an adolescent.
abstract: We reported on an adolescent who suffered from cholestatic hepatitis after taking a low dose of paracetamol. It was suspected that the condition was brought about by an allergic reaction to paracetamol. Paracetamol is one of the representative intrinsic hepatotoxic drugs. There have been only a few reports on liver damage due to an allergic reaction to paracetamol. There is a need to call attention to this particular reaction.
authors.affiliation: The Second Department of Internal Medicine, Yamagata University School of Medicine, Japan. shinzawa@okitama-hp.or.jp
authors.forename: H
authors.initials: H
authors.lastname: Shinzawa
authors.forename: H
authors.initials: H
authors.lastname: Togashi
authors.forename: K
authors.initials: K
authors.lastname: Sugahara
authors.forename: M
authors.initials: M
authors.lastname: Ishibashi
authors.forename: Y
authors.initials: Y
authors.lastname: Terui
authors.forename: M
authors.initials: M
authors.lastname: Aoki
authors.forename: H
authors.initials: H
authors.lastname: Mitsuhashi
authors.forename: T
authors.initials: T
authors.lastname: Matsuo
authors.forename: H
authors.initials: H
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Abe
authors.forename: S
authors.initials: S
authors.lastname: Ohno
authors.forename: K
authors.initials: K
authors.lastname: Saito
authors.forename: T
authors.initials: T
authors.lastname: Saito
authors.forename: N
authors.initials: N
authors.lastname: Yamada
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: R
authors.initials: R
authors.lastname: Horiuchi
mesh_terms: D000082:Acetaminophen / Q000009:adverse effects*; D000208:Acute Disease; D000293:Adolescent; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects*; D001663:Bilirubin / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D002780:Cholestasis, Intrahepatic / Q000139:chemically induced*; D004342:Drug Hypersensitivity / Q000473:pathology; D005260:Female; D006525:Hepatitis, Viral, Human / Q000821:virology; D006801:Humans; D008111:Liver Function Tests; D008213:Lymphocyte Activation
chemical_list: D018712:Analgesics, Non-Narcotic; D000082:Acetaminophen; D001663:Bilirubin