Effects of radiation and chemical exposures on cancer mortality among Rocketdyne workers: a review of three cohort studies.
The purpose of the UCLA Rocketdyne Study was to estimate the effects of occupational exposures to low-level ionizing radiation and selected chemicals on cancer mortality among nuclear and aerospace workers who were employed at Rocketdyne/Atomics International between 1950 and 1993. The results of this retrospective cohort study suggest that: (1) exposure to external radiation, especially doses greater than 200 mSv, increased the risk of dying from lymphopoietic cancers, lung cancer, and possibly other solid cancers; (2) exposure to internal radiation increased the risk of dying from lymphopoietic cancers and upper-aerodigestive-tract cancers; and (3) exposure to hydrazine or other chemicals associated with the same jobs at rocket-engine test stands increased the risk of dying from lung cancer and possibly other cancers.
Morgenstern
H
H
Department of Epidemiology, Center for Occupational and Environmental Health, UCLA School of Public Health, 90095-1772, USA.
Ritz
B
B
D002140:California / Q000453:epidemiology; D015331:Cohort Studies; D015989:Healthy Worker Effect; D006801:Humans; D006834:Hydrazines / Q000009:adverse effects*; D008175:Lung Neoplasms / Q000401:mortality; D008232:Lymphoproliferative Disorders / Q000401:mortality; D009369:Neoplasms / Q000139:chemically induced / Q000401:mortality*; D009381:Neoplasms, Radiation-Induced / Q000401:mortality*; D009784:Occupational Diseases / Q000139:chemically induced / Q000401:mortality*; D016273:Occupational Exposure
D006834:Hydrazines