Twins and cerebral palsy.
In a national follow-up study of twin births, monozygous compared with dizygous twins were at significantly increased for both to die in utero, one to die in utero and the co-twin to die in infancy, or both to be livebirths but both die in infancy. The prevalence of cerebral palsy among survivors of a co-twin fetal death was 80.2 and other cerebral impairment was 107.0 per 1000. Many apparently singleton cases of cerebral palsy and impairment may be due to fetal death of a twin that has not been recognized or has been recognized but not registered.
Pharoah
P O
PO
Department of Public Health, University of Liverpool, UK. p.o.d.pharoah@liv.ac.uk
D002547:Cerebral Palsy / Q000453:epidemiology* / Q000235:genetics; D004200:Diseases in Twins / Q000453:epidemiology* / Q000235:genetics; D005260:Female; D005313:Fetal Death / Q000453:epidemiology / Q000235:genetics; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012307:Risk Factors