[Persistent hyperglycemia and hyperinsulinemia in a newborn infant].
Management of neonatal hyperglycemia is complex, especially in immature newborns. Etiology is diverse, the most frequent cause being iatrogeny. Neonatal diabetes mellitus is a rare cause of hyperglycemia during the first days of life. Insulin treatment is sometimes required to control the condition. When insulin requirements exceed 2I U/kg/day insulin resistance syndrome should be suspected. We present the case of a newborn infant with Donohue syndrome, or leprechaunism, which is a rare, genetically determined dysmorphic syndrome leading to significant insulin resistance.
Tapia Ceballos
L
L
Area de Pediatría, Hospital Costa del Sol. Marbella, Málaga. leotapiaceb@hotmail.com
Romero Sánchez
J
J
Picazo Angelin
B
B
Díaz Cabrera
R
R
Romero González
J
J
D000015:Abnormalities, Multiple; D006801:Humans; D006943:Hyperglycemia / Q000150:complications* / Q000209:etiology; D006946:Hyperinsulinism / Q000150:complications* / Q000209:etiology; D007231:Infant, Newborn; D007333:Insulin Resistance; D008297:Male; D013577:Syndrome