title: [Evaluation of aqueous compartments of the body by integral bioimpedance spectrometry in x-ray surgical interventions in children].
abstract: There were studied 14 children (mean age 5.71 +/- 0.60 years, body weight 18.95 +/- 3.50 kg, height 101.0 +/- 4.03 cm) with initially normal osmotic and volumic status. Plasma osmolarity, blood aldosterone level, aqueous compartments balance were (evaluated by segmented bioimpedance spectrometry), urine osmolarity and diuresis were investigated after bolus injection of x-ray contrast agent (RCA) urografin-60% (mean volume 2 ml/kg for 2-4 sec). A statistically significant gradual decrease in the total volume of water (TVW) in the organism was observed, with 8.53% deficiency of TVW by the second hour after RCA injection in comparison with the initial level. TVW deficiency developed as the result of diuresis which increased 7-fold in the presence of increased plasma osmolarity after injection of RCA bolus. Correction of the volume of circulating blood and plasma was carried out mainly at the expense of intracellular liquid, whose deficiency was actually 4.5 times higher than of extracellular liquid. Bioimpedance spectrometry indicated centralized redistribution of water in the organism, as TVW deficiency was mainly due to water in the limbs. The results indicate the need in infusion therapy after RCA injection in order to correct the resultant water deficit.
authors.forename: V V
authors.initials: VV
authors.lastname: Lazarev
authors.forename: V A
authors.initials: VA
authors.lastname: Mikhel'son
authors.forename: S V
authors.initials: SV
authors.lastname: Kotova
authors.forename: I E
authors.initials: IE
authors.lastname: Galibin
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Poliaev
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Vodolazov
authors.forename: D V
authors.initials: DV
authors.lastname: Nikolaev
mesh_terms: D000367:Age Factors; D000450:Aldosterone / Q000097:blood; D001810:Blood Volume; D001825:Body Fluid Compartments; D001827:Body Height; D001835:Body Weight; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media; D003974:Diatrizoate Meglumine; D004231:Diuresis; D006801:Humans; D009994:Osmolar Concentration; D009995:Osmosis; D010953:Plasma Volume; D016634:Radiosurgery; D013997:Time Factors; D014567:Urography
chemical_list: D003287:Contrast Media; D003974:Diatrizoate Meglumine; D000450:Aldosterone