title: Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.
abstract: To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [(13)C]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.
authors.affiliation: Department of Infectious Diseases, Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Sakamoto
authors.forename: M
authors.initials: M
authors.lastname: Igarashi
authors.forename: K
authors.initials: K
authors.lastname: Kimura
authors.forename: A
authors.initials: A
authors.lastname: Takagi
authors.forename: T
authors.initials: T
authors.lastname: Miwa
authors.forename: Y
authors.initials: Y
authors.lastname: Koga
mesh_terms: D005260:Female; D016481:Helicobacter Infections / Q000097:blood / Q000628:therapy*; D016480:Helicobacter pylori / Q000502:physiology*; D006801:Humans; D007778:Lactobacillus / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D020116:Pepsinogen A / Q000097:blood; D020115:Pepsinogen C / Q000097:blood; D019936:Probiotics / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D020115:Pepsinogen C; D020116:Pepsinogen A