Giant cell arteritis and secondary amyloidosis: the natural history.
Giant cell (temporal) arteritis (GCA) may be a cause of fever of unknown origin (FUO) in elderly patients. The development of secondary (reactive) amyloidosis is an unusual complication of the disease. We describe a 65-year-old male patient who was hospitalized in our hospital with FUO and was diagnosed as having GCA 5 years later. At that time, he also had a nephrotic syndrome and secondary amyloidosis (AA-type). He died due to end-stage renal failure. The probable explanation for the development of this rare complication might be the late diagnosis of this chronic inflammatory disease, which was left untreated for a long period of time.
Altiparmak
M R
MR
Department of Nephrology, Cerrahpasa Medical Faculty, University of Istanbul, Turkey.
Tabak
F
F
Pamuk
O N
ON
Pamuk
G E
GE
Mert
A
A
Aktuğlu
Y
Y
D000368:Aged; D000682:Amyloid / Q000032:analysis / Q000145:classification; D000686:Amyloidosis / Q000209:etiology* / Q000473:pathology; D017809:Fatal Outcome; D005335:Fever of Unknown Origin / Q000209:etiology / Q000473:pathology; D013700:Giant Cell Arteritis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000209:etiology / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D013699:Temporal Arteries / Q000473:pathology
D000682:Amyloid; D011241:Prednisone