Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans.
To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [(13)C]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.
Sakamoto
I
I
Department of Infectious Diseases, Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan.
Igarashi
M
M
Kimura
K
K
Takagi
A
A
Miwa
T
T
Koga
Y
Y
D005260:Female; D016481:Helicobacter Infections / Q000097:blood / Q000628:therapy*; D016480:Helicobacter pylori / Q000502:physiology*; D006801:Humans; D007778:Lactobacillus / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D020116:Pepsinogen A / Q000097:blood; D020115:Pepsinogen C / Q000097:blood; D019936:Probiotics / Q000627:therapeutic use*; D016896:Treatment Outcome
D020115:Pepsinogen C; D020116:Pepsinogen A