Therapeutic implications of fibroblast growth factors in traumatic spinal cord injury.
Neurological damage after acute traumatic spinal cord injury (SCI) results from both the primary mechanical injury as well as the subsequent activation of cell death cascades mediating delayed tissue damage. Since secondary injury following traumatic SCI is a tightly regulated process in which several neurotrophic factors seem to be implicated, administration of these proteins has a clinical interest. Fibroblast growth factor may be one of the agents to be used for the treatment of traumatic SCI.
Cuevas
P
P
Servicio de Histologia, Departamento de Investigación, Hospital Ramón y Cajal, E-28034, Madrid, Spain. pedro.cuevas@hrc.es
Carceller
F
F
D000818:Animals; D005346:Fibroblast Growth Factors / Q000627:therapeutic use*; D006801:Humans; D013119:Spinal Cord Injuries / Q000188:drug therapy* / Q000503:physiopathology*
D005346:Fibroblast Growth Factors