[Appraisal of fungistatic and fungicidal activities of quaternary compounds towards yeasts belonging to the genera Candida and Cryptococcus].
The fungistatic and fungicidal activities of five quaternary ammonium compounds towards Candida and Cryptococcus strains were determined using a bacteriological method adapted to mycological experiments. It could be deduced from this study that Cryptococcus in spite of the capsule around the cell were more sensitive than Candida and that the benzethonium chloride (BC) exhibited the most effective action against the whole yeasts. No resistance appeared, only Cryptococcus strain was less sensitive than the others.
Mathieu
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G
Laboratoire de Botanique, UFR de Pharmacie, BP 87900 - F 21079 Dijon Cedex.
Delcourt
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A
D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D001558:Benzethonium / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D003454:Cryptococcus / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*
D000891:Anti-Infective Agents, Local; D000935:Antifungal Agents; D000644:Quaternary Ammonium Compounds; D001558:Benzethonium