title: [Evaluation of the effectiveness of various protocols of antibiotic prophylaxis and therapy in pancreatic necrosis].
abstract: The efficiency of various protocols of antibiotic prophylaxis and therapy (APT) used in 63 patients with pancreonecrosis is analyzed. Early treatment with carbapenemes is the most effective in disseminated infectious pancreonecrosis requiring obligatory surgical treatment. Drug efficiency is the key factor in choosing APT for intensive care of patients with destructive pancreatitis.
authors.forename: B R
authors.initials: BR
authors.lastname: Gel'fand
authors.forename: M I
authors.initials: MI
authors.lastname: Filimonov
authors.forename: S Z
authors.initials: SZ
authors.lastname: Burnevich
authors.forename: E B
authors.initials: EB
authors.lastname: Gel'fand
authors.forename: E Ts
authors.initials: ETs
authors.lastname: Tsydenzhapov
authors.forename: B B
authors.initials: BB
authors.lastname: Orlov
authors.forename: A N
authors.initials: AN
authors.lastname: Briukhov
mesh_terms: D018806:APACHE; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D001419:Bacteria / Q000302:isolation & purification; D015780:Carbapenems / Q000008:administration & dosage / Q000627:therapeutic use*; D003422:Critical Care; D006801:Humans; D008875:Middle Aged; D009336:Necrosis; D010179:Pancreas / Q000473:pathology; D010195:Pancreatitis / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology / Q000517:prevention & control / Q000601:surgery; D012720:Severity of Illness Index; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems