An unknown FVIII-inactivating substance derived from endothelial cells inhibits the intrinsic tenase complex.
Bombeli
T
T
Coagulation Laboratory, Division of Haematology, Department of Medicine, University Hospital, Zurich, Switzerland. thomas.bombeli@dim.usz.ch
Woodtli
K
K
Haeberli
A
A
D000925:Anticoagulants / Q000494:pharmacology; D000990:Antithrombin III / Q000494:pharmacology; D018929:Cell Culture Techniques / Q000379:methods; D003029:Coagulants / Q000494:pharmacology; D003546:Cysteine Endopeptidases / Q000187:drug effects*; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism*; D005169:Factor VIII / Q000037:antagonists & inhibitors*; D015951:Factor Xa / Q000187:drug effects; D065427:Factor Xa Inhibitors; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D007700:Kinetics; D008863:Microspheres; D009363:Neoplasm Proteins
D000925:Anticoagulants; D003029:Coagulants; D065427:Factor Xa Inhibitors; D009363:Neoplasm Proteins; D000990:Antithrombin III; D005169:Factor VIII; D015951:Factor Xa; D003546:Cysteine Endopeptidases; C030910:cancer procoagulant