title: Dysesthesia perceived as painful spasticity: A report of 3 cases.
abstract: Lesions of the central nervous system often involve the pyramidal tracts and the sensory pathways to produce spasticity, paresthesias, and dysesthesia. Three patients with intractable spasticity were treated with intrathecal baclofen. Two had an implanted Medtronic SynchroMed pump for long-term delivery of the muscle relaxant. The third patient had undergone a screening trial in which the baclofen was delivered into the intrathecal space through a lumbar catheter. All had excellent relief of spasms on clinical examination, but they reported painful spasms particularly at night. Two of the patients were successfully treated for dysesthesia.
authors.affiliation: Department of Neurosurgery, Boston Medical Center, and Boston University School of Medicine, Boston, MA, USA. jordia@bu.edu
authors.forename: J I
authors.initials: JI
authors.lastname: Ordia
authors.forename: E
authors.initials: E
authors.lastname: Fischer
authors.forename: E
authors.initials: E
authors.lastname: Adamski
authors.forename: E L
authors.initials: EL
authors.lastname: Spatz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001418:Baclofen / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction / Q000187:drug effects; D009125:Muscle Relaxants, Central / Q000008:administration & dosage; D009128:Muscle Spasticity / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D010292:Paresthesia / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen