title: Efficacy of 'functional relaxation' in comparison to terbutaline and a 'placebo relaxation' method in patients with acute asthma. A randomized, prospective, placebo-controlled, crossover experimental investigation.
abstract: BACKGROUND
  'Functional relaxation' (FR) according to Marianne Fuchs is a body-oriented psychotherapy that involves teaching the patient a type of relaxation techniques aimed at maintaining equilibrium of the nervous system.
  
  
  METHODS
  In order to determine whether the practice of elementary parts of this therapy has an immediate beneficial effect on pulmonary function, a randomized, single-blind, prospective crossover study was done with 21 asthmatics with acute bronchoconstriction. On 3 consecutive days they were given either (1) a 5-min verbal standard instruction in elementary exercises of FR (eFR), which they were to practice during subsequent bodyplethysmographic measurement or (2) inhalative terbutaline (IT), a beta(2)-sympathomimetic drug, or (3) an unspecific 'placebo relaxation' technique (PRT), so that all subjects tried all 3 treatments in random order. Spirometric variables were assessed.
  
  
  RESULTS
  There was a significant decrease in specific airway resistance with eFR, which, though not as pronounced as with IT, was significantly greater than with PRT. This study shows that clinically relevant effects can be achieved for patients with asthma through mind-body interaction, which can be triggered by reproducible procedures.
  
  
  CONCLUSIONS
  Further development of the FR approach could lead to a nonpharmacological and effective supplementary treatment for asthma, which is in high demand by many patients.
authors.affiliation: Department of Psychosomatic Medicine and Psychotherapy, Biometry and Epidemiology, University of Erlangen, Germany. thomas.loew@psych.med.uni-erlangen.de
authors.forename: T H
authors.initials: TH
authors.lastname: Loew
authors.forename: K
authors.initials: K
authors.lastname: Tritt
authors.forename: W
authors.initials: W
authors.lastname: Siegfried
authors.forename: H
authors.initials: H
authors.lastname: Bohmann
authors.forename: P
authors.initials: P
authors.lastname: Martus
authors.forename: E G
authors.initials: EG
authors.lastname: Hahn
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D001249:Asthma / Q000188:drug therapy / Q000628:therapy*; D018592:Cross-Over Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012064:Relaxation Therapy; D016037:Single-Blind Method; D013566:Sympathomimetics / Q000627:therapeutic use*; D013726:Terbutaline / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D013566:Sympathomimetics; D013726:Terbutaline