title: [Features of the association of Helicobacter pylori infection and ulcer in Europeans and Mongoloids in Siberia].
abstract: OBJECTIVE
  To study association between Helicobacter Pylori infection in ulcer in native population and migrants in Siberia.
  
  
  METHODS
  Epidemiological survey of ulcer has been performed in Northern (Evenkia, Yakutia) and Southern (Khakasia) regions of Siberia. Clinical examination covered 3908 Europeoids (Russians, Ukrainians) and 1999 Mongoloids (Evenks, Evens, Khakases). Endoscopic examination was made in 2144 patients. Light microscopy has detected Helicobacter pylori (HP) in 453 patients (215 migrants and 238 natives).
  
  
  RESULTS
  Prevalence of ulcer in the South of Siberia was 6.1 and 1.5% for migrants and natives, respectively. In the North--8.9 and 0.6%, respectively. HP was diagnosed in 83.7% of Mongoloids and 69.2% of Europeoids in the South and 92.2 and 100%, respectively, in the North. HP index, contamination and adhesion in migrants were higher than in native population.
  
  
  CONCLUSIONS
  Siberial Europeoids and Mongoloids have specific ethnic features of ulcer occurrence and its association with HP. Native population is protected better from the pathogenic bacteria. Further study of the causes of virulent bacterial properties and mechanisms maintaining long persistance of HP in the stomach is necessary.
authors.forename: V V
authors.initials: VV
authors.lastname: Tsukanov
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Tonkikh
authors.forename: S V
authors.initials: SV
authors.lastname: Barkalov
authors.forename: O V
authors.initials: OV
authors.lastname: Shtygasheva
authors.forename: A G
authors.initials: AG
authors.lastname: Gitlina
authors.forename: O L
authors.initials: OL
authors.lastname: Garkun
mesh_terms: D044466:Asian People; D004381:Duodenal Ulcer / Q000150:complications / Q000453:epidemiology; D005260:Female; D016481:Helicobacter Infections / Q000150:complications / Q000453:epidemiology*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D010437:Peptic Ulcer / Q000150:complications / Q000453:epidemiology*; D012424:Rural Population; D012737:Sex Factors; D012800:Siberia / Q000453:epidemiology; D013276:Stomach Ulcer / Q000150:complications / Q000453:epidemiology; D044465:White People