Ukrain: a novel antitumor drug.
A review of the recent literature on the new anticancer drug Ukrain is provided herein. We review Ukrain, a thiophosphate derivative of alkaloids from Chelidonium majus L., its capacity to exert selective cytotoxic and cytostatic effects on tumor cells, simultaneously acting as an immune response modifier, its good tolerance and lack of side effects even after long-term application, perspectives of the application of this drug in oncology.
Uglyanitsa
K N
KN
Medical Institute of Grodno, ul Gorkogo 80, 230015 Grodno, Belarus.
Nefyodov
L I
LI
Doroshenko
Y M
YM
Nowicky
J W
JW
Volchek
I V
IV
Brzosko
W J
WJ
Hodysh
Y J
YJ
D000470:Alkaloids / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D001600:Berberine Alkaloids; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy; D010617:Phenanthridines
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D001600:Berberine Alkaloids; D010617:Phenanthridines; C060921:ukrain