title: Presence of ochratoxin A in human milk in relation to dietary intake.
abstract: Individual and geographical variations in ochratoxin A (OA) levels in human blood and milk samples may be due to differences in dietary habits. The purpose of this study was to examine the relationship between OA contamination of human milk and dietary intake. Human milk samples were collected from 80 Norwegian women. The usual food intake during the last year was recorded using a quantitative food frequency questionnaire. The concentration of OA in the human milk was determined by HPLC (detection limit 10 ng/l). Seventeen (21%) out of 80 human milk samples contained OA in the range 10-182 ng/l. The women with a high dietary intake of liver paste (liverwurst, liver pâté) and cakes (cookies, fruitcakes, chocolate cakes, etc.) were more likely to have OA-contaminated milk. The risk of OA contamination was also increased by the intake of juice (all kinds). In addition, the results indicate that breakfast cereals, processed meat products, and cheese could be important contributors to dietary OA intake. OA contamination of the milk was unrelated to smoking, age, parity, and anthropometric data other than body weight.
authors.affiliation: Department of Agriculture and Natural Science, Hedmark College, Ridabu, Norway. Marit.Skaug@spe.hihm
authors.forename: M A
authors.initials: MA
authors.lastname: Skaug
authors.forename: I
authors.initials: I
authors.lastname: Helland
authors.forename: K
authors.initials: K
authors.lastname: Solvoll
authors.forename: O D
authors.initials: OD
authors.lastname: Saugstad
mesh_terms: D000328:Adult; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D002273:Carcinogens / Q000032:analysis*; D016009:Chi-Square Distribution; D002851:Chromatography, High Pressure Liquid; D004032:Diet; D015930:Diet Records; D005260:Female; D006801:Humans; D016015:Logistic Models; D008895:Milk, Human / Q000737:chemistry*; D009793:Ochratoxins / Q000032:analysis*; D012621:Seasons; D018709:Statistics, Nonparametric
chemical_list: D002273:Carcinogens; D009793:Ochratoxins; C025589:ochratoxin A