title: Response of radiochemotherapy-associated cerebral edema to a phytotherapeutic agent, H15.
abstract: Twelve patients with brain tumors and progressive edema caused by tumor progression or radiochemotherapy-related leukoencephalopathy were treated with H15, a phytotherapeutic anti-inflammatory agent. Edema was reduced in two of seven patients with glioblastoma with tumor progression and in three of five patients with treatment-related leukoencephalopathy. All patients with leukoencephalopathy improved clinically for several months.
authors.affiliation: Department of Neurology, University of Tübingen, Medical School, Tübingen, Germany.
authors.forename: J R
authors.initials: JR
authors.lastname: Streffer
authors.forename: M
authors.initials: M
authors.lastname: Bitzer
authors.forename: M
authors.initials: M
authors.lastname: Schabet
authors.forename: J
authors.initials: J
authors.lastname: Dichgans
authors.forename: M
authors.initials: M
authors.lastname: Weller
mesh_terms: D000328:Adult; D000368:Aged; D001929:Brain Edema / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D001932:Brain Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use*; D014315:Triterpenes / Q000627:therapeutic use*
chemical_list: D010936:Plant Extracts; D014315:Triterpenes; C054625:boswellic acid