title: Bronchospasm induced by cardiopulmonary bypass.
abstract: Severe bronchospasm during cardiopulmonary bypass (CPB) is an unusual event. A 16-year-old girl with pulmonary stenosis who underwent reconstruction of the right ventricle outflow tract experienced severe bronchospasm following CPB. Just after the initiation of the partial CPB, high inspiratory airway pressure was suddenly recognized. The lung had become too stiff for the anesthetic circuit bag to be squeezed by hand. Tracheobronchial obstruction was ruled out by investigation with a fiberoptic bronchoscope. A presumptive diagnosis of severe bronchospasm was made, and aggressive bronchodilator therapy was instituted. The attack was successfully treated with aggressive bronchodilator therapy. Although the exact causes for bronchospasm in our case are not clear, CPB factors, such as the release of complements and allergic reactions might have induced the attack under relatively light anesthetic state.
authors.affiliation: Department of Anesthesiology, Tokushima University School of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Kawahito
authors.forename: H
authors.initials: H
authors.lastname: Kitahata
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: J
authors.initials: J
authors.lastname: Nozaki
authors.forename: S
authors.initials: S
authors.lastname: Oshita
mesh_terms: D000293:Adolescent; D000777:Anesthetics / Q000009:adverse effects; D001986:Bronchial Spasm / Q000188:drug therapy / Q000209:etiology*; D001993:Bronchodilator Agents / Q000627:therapeutic use; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011666:Pulmonary Valve Stenosis / Q000601:surgery*
chemical_list: D000777:Anesthetics; D001993:Bronchodilator Agents