title: Quantitative assessment of in vitro jets based on three-dimensional color Doppler reconstruction.
abstract: Three-dimensional (3-D) color Doppler imaging of flow jets was performed to investigate the effects of flow rate and orifice size on jet volumes. Flow jets were generated using a flow model to simulate mitral regurgitation. This flow model consisted of a ventricular chamber, a valvular plate and an atrial chamber. Steady flow was driven through circular orifices having diameters of 2.5, 3.5, 4.5, and 6 mm, respectively, with flow rates of 5, 10, 15, 20, and 25 mL/s to form free jets in the atrial chamber. An ATL Ultramark 9 HDI system was used to perform 3-D color Doppler imaging of the flow jets. A transesophageal probe was rotated by a stepper motor to create 3-D color Doppler images of the jets. The color jet volumes for different hemodynamic conditions were measured and then compared with the theoretical predictions. Results showed that the jet volume estimated from the 3-D color Doppler was directly proportional to the flow rate and inversely proportional to the orifice size. The estimated jet volumes correlated well (r > 0.95) with theoretical predictions. This study supports the use of color jet volume as a parameter to quantify mitral regurgitation.
authors.affiliation: Department of Electrical and Computer Engineering, The George Washington University, Washington, DC 20052, USA. zguo@seas.gwu.edu
authors.forename: Z
authors.initials: Z
authors.lastname: Guo
authors.forename: D R
authors.initials: DR
authors.lastname: Boughner
authors.forename: J M
authors.initials: JM
authors.lastname: Dietrich
authors.forename: P W
authors.initials: PW
authors.lastname: Pflugfelder
authors.forename: L G
authors.initials: LG
authors.lastname: Durand
authors.forename: M
authors.initials: M
authors.lastname: Loew
authors.forename: A
authors.initials: A
authors.lastname: Fenster
mesh_terms: D001783:Blood Flow Velocity; D018618:Echocardiography, Doppler, Color; D019560:Echocardiography, Three-Dimensional; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008955:Models, Cardiovascular; D008961:Models, Structural