title: Isolation and expression of a gene (CGR1) regulated during the yeast-hyphal transition in Candida albicans.
abstract: We used RNA fingerprinting of arbitrarily primed PCR to isolate genes upregulated during the yeast-hyphal transition in Candida albicans. The sequence and expression of one of these genes (CGR1, Candida growth regulation) are presented. Our results suggest that CGR1 expression is associated with a growth cessation of yeast cells, a prerequisite for germination in this organism.
authors.affiliation: Department of Oral Microbiology, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan. chot1@college.fdcnet.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Cho
authors.forename: M
authors.initials: M
authors.lastname: Sudoh
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Nakashima
authors.forename: H
authors.initials: H
authors.lastname: Chibana
authors.forename: H
authors.initials: H
authors.lastname: Kaminishi
mesh_terms: D000595:Amino Acid Sequence; D015152:Blotting, Northern; D002176:Candida albicans / Q000235:genetics* / Q000254:growth & development; D005656:Fungal Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics*; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012331:RNA, Fungal / Q000302:isolation & purification; D016415:Sequence Alignment
chemical_list: C426046:CGR1 protein, Candida albicans; D005656:Fungal Proteins; D012331:RNA, Fungal