From 5 fluorouracil to the new oral fluoropyrimidines: a brief overview of four decades of clinical investigations.
Sulkes
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Institute of Oncology, Rabin Medical Center (Beilinson Campus), Petah Tiqva, Israel. asolkes@ccsg.tau.ac.il
D000284:Administration, Oral; D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy*; D011743:Pyrimidines / Q000008:administration & dosage / Q000627:therapeutic use*
D000964:Antimetabolites, Antineoplastic; D011743:Pyrimidines; D005472:Fluorouracil