title: [Reduction of hematogenous infection in HIV positive patients following highly active antiretroviral therapy].
abstract: BACKGROUND
  Bloodstream infections have probably decreased in HIV patients since highly active antiretroviral therapy (HAART) usage.
  
  
  METHODS
  Hematogenous infections, including mycobacteria and fungi in HIV patients, stratified into two periods (I: 1995-1996 and II: 1997-1998) were included to evaluate changes attributable to HAART.
  
  
  RESULTS
  226 episodes were attended (incidence: 38.8 in period I and 15.3 in period II; p < 0.01). A significant decrease was observed in immunosuppression related microorganisms. HAART usage increased from 6.4% in period I to 31.2% in period II. Immunological parameters of HIV patients significantly improved in period II.
  
  
  CONCLUSIONS
  Hematogenous infections have significantly decreased in HIV patients since the use of HAART.
authors.affiliation: Unidades de Enfermedades Infecciosas. Hospital Universitari Germans Trias i Pujol. Badalona. Barcelona. umi@ns.hugtip.es
authors.forename: M
authors.initials: M
authors.lastname: Luisa Pedro-Botet
authors.forename: J
authors.initials: J
authors.lastname: Maria Mòdol
authors.forename: X
authors.initials: X
authors.lastname: Vallés
authors.forename: E
authors.initials: E
authors.lastname: Reynaga
authors.forename: J
authors.initials: J
authors.lastname: Romeu
authors.forename: M
authors.initials: M
authors.lastname: Juan
authors.forename: N
authors.initials: N
authors.lastname: Sopena
authors.forename: M
authors.initials: M
authors.lastname: Sabriá Leal
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology*; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D008297:Male; D018805:Sepsis / Q000453:epidemiology*
chemical_list: D019380:Anti-HIV Agents