title: Cissus stem gum as potential dispersant in pharmaceutical liquid systems: rheological characterization.
abstract: A Co-axial viscometer, the Haake-Rotovisco, was used studying the rheological behaviour of aqueous dispersion of cissus stem gum. At concentrations of 4% w/v and above, the mucilage is both pseudoplastic and thixotropic. Two equations derived from a power law expression for apparent viscosity(h): h = ekc + b were solved simultaneously (c = 4 and 8% w/v) in the determination of material constants k and b for cissus gum. The apparent viscosity of the polymeric liquid system was affected by concentration of the gum, pH, temperature and aging.
authors.affiliation: Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka, Nigeria.
authors.forename: J
authors.initials: J
authors.lastname: Alfa
authors.forename: A
authors.initials: A
authors.lastname: Chukwu
authors.forename: O K
authors.initials: OK
authors.lastname: Udeala
mesh_terms: D000269:Adhesives; D004355:Drug Stability; D005079:Excipients / Q000737:chemistry*; D019999:Pharmaceutical Solutions / Q000737:chemistry*; D053149:Plant Gums; D011134:Polysaccharides; D012212:Rheology; D013696:Temperature
chemical_list: D000269:Adhesives; C429904:Cissus stem gum; D005079:Excipients; D019999:Pharmaceutical Solutions; D053149:Plant Gums; D011134:Polysaccharides