The mutual benefit role of liver and pancreas in combined transplantation.
The present study observed the mutual benefit role of liver and pancreas in combined hepaticopancreatic transplantation in rats. The results indicated that pancreas, when transplanted with liver, could survive for a significant long time (13.4 +/- 1.01 days) than it transplanted alone (9.2 +/- 1.14 days) (P < 0.05, t test). The interstitial rejection was mild and its rejection grade was significantly different from that of pancreas transplanted alone (P < 0.05, X2 test). The liver, when transplanted with pancreas, regenerated with strong competence and contact structure morphologically compared with liver transplanted alone. We think that pancreas could be immunologically protected against rejection and liver can be nutritionalized by pancreas in combined liver and pancreas transplantation.
Qiao
H
H
Department of Surgery, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730.
Meng
L
L
Xiao
Y
Y
Zhu
Y
Y
D000818:Animals; D008099:Liver / Q000502:physiology*; D016031:Liver Transplantation / Q000379:methods; D008297:Male; D010179:Pancreas / Q000502:physiology*; D016035:Pancreas Transplantation / Q000379:methods; D051381:Rats; D011917:Rats, Inbred Lew; D017207:Rats, Sprague-Dawley; D017208:Rats, Wistar