Postinfantile giant cell hepatitis complicating ulcerative colitis: a case report and review of the literature.
Giant cell hepatitis is common in the neonatal period. When present in adults, it is known as postinfantile giant cell hepatitis (PGCH). PGCH can arise in the context of viral, drug-related, and autoimmune disorders but, in many other cases, its etiology remains unclear. We report a case of PGCH occurring in the setting of autoimmune hepatitis and ulcerative colitis. This case highlights the close association between PGCH and autoimmune disorders and the need to recognize it as a hepatic complication of inflammatory bowel disease.
Labowitz
J
J
Department of Medicine, University of Pittsburgh School of Medicine, Pennsylvania, USA.
Finklestein
S
S
Rabinovitz
M
M
D000328:Adult; D000367:Age Factors; D003093:Colitis, Ulcerative / Q000150:complications*; D015726:Giant Cells; D006505:Hepatitis / Q000150:complications* / Q000473:pathology*; D006801:Humans; D008297:Male