Treatment of central post-stroke pain with oral ketamine.
Case report of 68 year old female with central post-stroke pain successfully treated with oral ketamine. The patient's pain was refractory to conventional pain treatments and she had persistent right hemi-body neuropathic pain with allodynia and hyperalgesia. An intravenous ketamine trial, followed by oral ketamine with titration to 50mg three times a day was beneficial in decreasing allodynia and hyperalgesia, as well as improving functional capabilities. Known side effects including dysphoria, hallucinations, and paranoid feelings were attenuated with benzodiazepines.
Vick
P G
PG
Department of Anesthesiology, University of North Carolina at Chapel Hill, Campus Box # 7010, Chapel Hill, NC 27599-7010, USA. pvick@aims.unc.edu
Lamer
T J
TJ
D000284:Administration, Oral; D000368:Aged; D000700:Analgesics / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006930:Hyperalgesia / Q000188:drug therapy / Q000209:etiology; D007649:Ketamine / Q000008:administration & dosage*; D009437:Neuralgia / Q000188:drug therapy* / Q000209:etiology; D020521:Stroke / Q000150:complications
D000700:Analgesics; D007649:Ketamine