title: [Hepatic disorders related to Lyme disease. Study of two cases and a review of the literature].
abstract: We report two cases of Lyme disease, revealed by hepatic damage in a 71- and a 59-year old man. In the first case, the disease was revealed by febrile jaundice whereas, in the second case, results of liver tests showed cytolytic and cholestatic abnormalities with fever. Lyme disease is a zoonosis due to infection by Borrelia burdorferi transmitted by ticks. The multiple phases of the disease explain the polymorphism of the clinical manifestations. Usually, extrahepatic symptoms are first observed, including neurological tropisms of Borrelia burdorferi. On the contrary, hepatic impairment due to Lyme disease is rare, often asymptomatic and with biological manifestations only.
authors.affiliation: Service d'Hépato-Gastroentérologie, CHU, Hôpital Nord, Amiens. dadamessi@free.fr
authors.forename: I
authors.initials: I
authors.lastname: Dadamessi
authors.forename: F
authors.initials: F
authors.lastname: Brazier
authors.forename: A
authors.initials: A
authors.lastname: Smaïl
authors.forename: R
authors.initials: R
authors.lastname: Delcenserie
authors.forename: J L
authors.initials: JL
authors.lastname: Dupas
authors.forename: J P
authors.initials: JP
authors.lastname: Capron
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D002780:Cholestasis, Intrahepatic / Q000378:metabolism / Q000382:microbiology* / Q000473:pathology; D005334:Fever / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008107:Liver Diseases / Q000378:metabolism / Q000382:microbiology* / Q000473:pathology; D008111:Liver Function Tests; D008193:Lyme Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission; D008297:Male; D008875:Middle Aged; D015047:Zoonoses / Q000635:transmission