title: Thromboembolism complicating thrombin injection of femoral artery pseudoaneurysm: management with intraarterial thrombolysis.
abstract: Ultrasound (US)-guided compression of pseudoaneurysms is being rapidly replaced by US-guided percutaneous treatment with thrombin injection because of the less intensive nature of this procedure. Thromboembolism after percutaneous treatment with thrombin injection is rare and has been described in brachial artery pseudoaneurysms. These were managed with intravenous administration of heparin and surgical thrombectomy. In this report, the authors describe thromboembolic complication of thrombin injection after treatment of a femoral artery pseudoaneurysm. This was managed by intraarterial thrombolysis with use of recombinant tissue plasminogen activator (rt-PA) with resolution of all major occlusive changes. A lower dose of thrombin injection and frequent postprocedural monitoring of distal pulses is recommended.
authors.affiliation: Department of Radiology, St. Joseph Mercy Hospital, 44405 Woodward Ave., Pontiac, Michigan 48341, USA. sadiq5@mediaone.net
authors.forename: S
authors.initials: S
authors.lastname: Sadiq
authors.forename: W
authors.initials: W
authors.lastname: Ibrahim
mesh_terms: D000368:Aged; D017541:Aneurysm, False / Q000188:drug therapy*; D005260:Female; D005263:Femoral Artery; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D013917:Thrombin / Q000008:administration & dosage / Q000009:adverse effects*; D013923:Thromboembolism / Q000188:drug therapy* / Q000209:etiology*; D015912:Thrombolytic Therapy / Q000379:methods*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D005343:Fibrinolytic Agents; D013917:Thrombin; D010959:Tissue Plasminogen Activator