[Ultrastructure and molecular biochemistry on pathogenic fungal cells: the architecture of septal cell walls of dermatophytes].
This review provides abstracts of our research for which the year 2000 prize of The Japanese Society for Medical Mycology was awarded. The study consists of 4 fields: 1)Ultrastructure and biochemistry of the cell walls of dermatophytes. 2) Freeze-fracture electron microscopic study on the membrane systems of pathogenic fungi. 3) Action mechanisms of antifungal agents in terms of membrane structure and functions. 4) Dimorphism and virulence of pathogenic fungi in terms of molecular biology of membrane lipids. Since the detailed contents of these studies were reported in my previous review article (Jpn J Med Mycol 41: 211-217, 2000), I would like to mention these studies only briefly here, together with a detailed review of the septal cell wall architecture of dermatophytes, which I did not cover in my earlier articles.
Kitajima
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Department of Dermatology, Gifu University School of Medicine, 40 Tsukasamachi, Gifu City 500-8705, Japan.
D000935:Antifungal Agents / Q000494:pharmacology; D003883:Arthrodermataceae / Q000166:cytology* / Q000472:pathogenicity; D002473:Cell Wall / Q000737:chemistry / Q000187:drug effects / Q000648:ultrastructure*; D005614:Freeze Fracturing; D008563:Membrane Lipids / Q000378:metabolism; D008854:Microscopy, Electron; D014774:Virulence
D000935:Antifungal Agents; D008563:Membrane Lipids