title: Tumefactive fibroinflammatory lesion of the neck with progressive invasion of the meninges, skull base, orbit, and brain.
abstract: Tumefactive fibroinflammatory lesions of the head and neck are rare. CNS involvement has not been reported. We present a histologically proven case of a tumefactive fibroinflammatory lesion that originated in the left side of the neck and progressed over 2 years to involve the meninges, the cavernous sinuses, the right temporal lobe, and the right orbit. The lesion caused destruction of the skull base and a subdural hematoma. The relationship of the present lesion to idiopathic hypertrophic pachymeningitis and Tolosa-Hunt syndrome is discussed.
authors.affiliation: Department of Radiology, New Jersey Medical School, University Hospital, 150 Bergen Street, Newark, NJ 07103, USA.
authors.forename: A I
authors.initials: AI
authors.lastname: Holodny
authors.forename: C F
authors.initials: CF
authors.lastname: Kirsch
authors.forename: M
authors.initials: M
authors.lastname: Hameed
authors.forename: G
authors.initials: G
authors.lastname: Sclar
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology*; D005355:Fibrosis; D006258:Head and Neck Neoplasms / Q000150:complications / Q000473:pathology*; D006408:Hematoma, Subdural / Q000209:etiology; D006801:Humans; D007249:Inflammation / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008578:Meninges / Q000473:pathology*; D009915:Orbit / Q000473:pathology*; D019291:Skull Base / Q000473:pathology*; D014057:Tomography, X-Ray Computed