Monocular elevator paresis in neurofibromatosis type 2.
A retrospective review of 29 consecutive unselected patients referred for neuro-ophthalmic evaluation after the diagnosis of neurofibromatosis type 2 (NF2) showed that four of them had a monocular elevator paresis. In two of the four MRI demonstrated lesions, presumed to be schwannomas, of the third nerve. These findings indicate that monocular elevator paresis is a common neuro-ophthalmic finding in NF2, which the authors suspect is probably a sign of third nerve infiltration or compression by a schwannoma.
Egan
R A
RA
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, 02114, USA.
Thompson
C R
CR
MacCollin
M
M
Lessell
S
S
D000293:Adolescent; D000328:Adult; D003390:Cranial Nerve Neoplasms / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009442:Neurilemmoma / Q000473:pathology; D016518:Neurofibromatosis 2 / Q000150:complications* / Q000473:pathology*; D015835:Ocular Motility Disorders / Q000150:complications* / Q000473:pathology*; D010291:Paresis / Q000150:complications* / Q000473:pathology*; D012189:Retrospective Studies