title: The investigation of major salivary gland agenesis: a case report.
abstract: Salivary gland agenesis is an extremely uncommon congenital anomaly, which may cause a profound xerostomia in children. The oral sequelae includes dental caries, candidosis, and ascending sialadenitits. The present report details a child with rampant dental caries secondary to xerostomia. Despite having oral disease for many years, the congenital absence of all the salivary glands failed to be established until early adulthood. The appropriate investigation and management of the xerostomic child allows a definitive diagnosis to be made and attention focused on the prevention and treatment of resultant oral disease.
authors.affiliation: Department of Oral Medicine, University College London. T.Hodgson@eastman.ucl.ac.uk
authors.forename: T A
authors.initials: TA
authors.lastname: Hodgson
authors.forename: R
authors.initials: R
authors.lastname: Shah
authors.forename: S R
authors.initials: SR
authors.lastname: Porter
mesh_terms: D002180:Candidiasis, Oral / Q000209:etiology; D002675:Child, Preschool; D003731:Dental Caries / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D012464:Saliva, Artificial / Q000627:therapeutic use; D012469:Salivary Glands / Q000002:abnormalities*; D014987:Xerostomia / Q000150:complications* / Q000209:etiology
chemical_list: D012464:Saliva, Artificial