title: MR imaging in two cases of subacute denervation change in the muscles of facial expression.
abstract: Denervation changes in muscle following damage to cranial and peripheral nerves can be observed on both CT and MR imaging studies. These findings are well described for cranial nerves (CN) V, X, XI, and XII. The CT findings of denervation atrophy due to CN VII dysfunction have been reported. We describe the MR imaging findings in two patients with perineural spread of tumor along CN VII. Both patients showed T2 prolongation and postcontrast enhancement in muscles of facial expression, suggestive of subacute denervation changes.
authors.affiliation: Department of Radiology, University of California-San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143-0628, USA.
authors.forename: N J
authors.initials: NJ
authors.lastname: Fischbein
authors.forename: M J
authors.initials: MJ
authors.lastname: Kaplan
authors.forename: R K
authors.initials: RK
authors.lastname: Jackler
authors.forename: W P
authors.initials: WP
authors.lastname: Dillon
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000503:physiopathology*; D005149:Facial Expression; D005152:Facial Muscles / Q000294:innervation* / Q000473:pathology; D005153:Facial Neoplasms / Q000175:diagnosis / Q000503:physiopathology*; D005154:Facial Nerve / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009361:Neoplasm Invasiveness