[Relationship between left cardiac function and oxygen transport of cor pulmonale during acute attack at high altitude].
OBJECTIVE
Relationship between left cardiac function and oxygen transport in the patients with cor pulmonale during acute attack at high altitude was studied to benefit prevention and treatment of cor pulmonale.


METHODS
20 cases were divided into 16 as a surviving group and 4 as a death group. CO was determined by Swan-Ganz catheter from internal carotid vein to pulmonary artery directly.


RESULTS
(1) CI in the patients decreased (2.9 +/- 0.4 L.min-1.m-2). mPAP (4.9 +/- 1.3 kPa) and PAWP (1.5 +/- 0.8 kPa) increased. LVSWI (35 +/- 11 g.cm-1.min-1) dropped. (2) above Indicies in surviving group improved after comprehensive treatment. CI and LVSWI increased. But LVSWI in death group continued to decline. mPAP and PAWP were not changed; (3) There was significant corelation between LVSVI and DO2(r = 0.4318, P < 0.05).


CONCLUSIONS
LVSWI of cor pulmonale could affect DO2 level directly and closely relate to prognosis.
Zhang
H
H
Qinghai Provincial People's Hospital, Xining 810007.
Sun
D
D
Tao
L
L
D000368:Aged; D000532:Altitude Sickness / Q000378:metabolism / Q000503:physiopathology*; D002302:Cardiac Output; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism*; D011660:Pulmonary Heart Disease / Q000378:metabolism / Q000503:physiopathology*; D011669:Pulmonary Wedge Pressure; D012189:Retrospective Studies; D016277:Ventricular Function, Left
D010100:Oxygen