title: [Characteristics of anesthesia in children operated on for extrahepatic portal hypertension].
abstract: Portocaval shunting reliably preventing hemorrhages from esophagogastric veins is most often used in surgery for extrahepatic portal hypertension (EPH) in children. Difficulties of anesthesia for this intervention consists in essential alteration of volume bloodflow as a result of massive outflow of deposited blood to systemic circulation through the new bypass. This necessitates search for an adequate method of general anesthesia and variants of infusion therapy for surgical venous shunting in children with EPH. Sixty-eight children aged 1-15 years with the EPH syndrome were subjected to elective surgery under general analgesia (multicomponent balanced neuroanesthesia with evaluation of some hemodynamic and metabolic parameters). The proposed protocol of general anesthesia in combination with epidural analgesia by local anesthetics and promedole and infusion therapy in the hypervolemic hemodilution mode create the most favorable conditions for adaptation of hemodynamics to increased preloand.
authors.forename: T P
authors.initials: TP
authors.lastname: Mishina
authors.forename: V A
authors.initials: VA
authors.lastname: Mikhel'son
authors.forename: S M
authors.initials: SM
authors.lastname: Stepanenko
authors.forename: O S
authors.initials: OS
authors.lastname: Geodakian
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Razumovskiĭ
mesh_terms: D000293:Adolescent; D000367:Age Factors; D015360:Analgesia, Epidural; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000768:Anesthesia, General; D001803:Blood Transfusion; D002648:Child; D002675:Child, Preschool; D006438:Hemodilution; D006439:Hemodynamics; D006801:Humans; D006975:Hypertension, Portal / Q000503:physiopathology / Q000601:surgery*; D007223:Infant; D011167:Portacaval Shunt, Surgical; D011396:Promedol / Q000627:therapeutic use
chemical_list: D000701:Analgesics, Opioid; D011396:Promedol