Werner syndrome cells are sensitive to DNA cross-linking drugs.
Poot
M
M
Department of Pathology, University of Washington, Seattle, Washington 98195-7705, USA. mpoot@u.washington.edu
Yom
J S
JS
Whang
S H
SH
Kato
J T
JT
Gollahon
K A
KA
Rabinovitch
P S
PS
D000970:Antineoplastic Agents / Q000494:pharmacology; D017209:Apoptosis; D002453:Cell Cycle / Q000187:drug effects / Q000502:physiology; D002460:Cell Line; D003432:Cross-Linking Reagents / Q000494:pharmacology*; D004247:DNA / Q000378:metabolism*; D004265:DNA Helicases / Q000235:genetics / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005090:Exodeoxyribonucleases; D006801:Humans; D007364:Intercalating Agents / Q000494:pharmacology*; D008214:Lymphocytes / Q000187:drug effects* / Q000473:pathology; D053484:RecQ Helicases; D014898:Werner Syndrome / Q000235:genetics / Q000473:pathology*; D000071657:Werner Syndrome Helicase
D000970:Antineoplastic Agents; D003432:Cross-Linking Reagents; D004791:Enzyme Inhibitors; D007364:Intercalating Agents; D004247:DNA; D005090:Exodeoxyribonucleases; D004265:DNA Helicases; D053484:RecQ Helicases; C098785:WRN protein, human; D000071657:Werner Syndrome Helicase