title: Delayed-focus pulses optimized using simulated annealing.
abstract: Unlike prefocused pulses and shaped pulses based on the linear response theory, delayed-focus pulses (X.-L. Wu et al., 1991, Magn. Reson. Med. 20, 165--170) produce a selective spin echo after a predefined short delay without using a pi refocusing pulse. In this paper, a series of delayed-focus pulses of different flip angles are proposed based on optimization using Fourier series representation and simulated annealing. The resistance of these delayed-focus pulses to T(2) relaxation is also demonstrated using numerical simulation of Bloch equations.
authors.affiliation: The Nathan S. Kline Institute, Orangeburg, New York 10962, USA.
authors.forename: J
authors.initials: J
authors.lastname: Shen
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D005583:Fourier Analysis; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*