title: Regressive biological evolution due to environmental change.
abstract: Simulation results are presented which suggest that regressive evolution (i.e., evolution to a less adapted state) often occurs in response to environmental change, by a process analogous to the stress-induced reversal of aging in glassy materials. The key to this process is the stress-induced disappearance of fitness optima that lead to irreversible changes in the location of a population in genotype space. Even though the population may always evolve to higher fitness states, this irreversible process will often act to bring an initially well-adapted system to a less adapted state upon a return to initial conditions.
authors.affiliation: Department of Chemical Engineering, Tulane University, New Orleans, LA 70118, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Lacks
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D005075:Biological Evolution; D004777:Environment; D005898:Glass; D008954:Models, Biological; D015233:Models, Statistical