title: Comparative study of neutrophil activities in adults and full-term neonates in relation to the method of delivery.
abstract: The aim of this study was to compare the markers of neutrophil activity in healthy adults with those in healthy neonates in relation to the method of delivery. The following parameters were studied: absolute neutrophil count, neutrophil adherence to nylon fiber, NBT reduction, and neutrophil phagocytosis of latex particles. The study has shown that the method of delivery significantly affects the markers of neutrophil activity measured in umbilical cord blood. The levels of these markers were higher in neonates born by elective cesarean section than in adults, neonates born vaginally or those born by emergency cesarean section. This comparative study of defensive functions of neutrophils from adults and neonates indicates that the conflicting results of other studies may be caused not only by differences in investigative methodology but also by the fact that the eligibility criteria used in these studies did not include the method of delivery, which can affect the markers of neutrophil activity via triggering a stress response.
authors.affiliation: Department of Neonatology, Medical University of Silesia, Katowice, Poland.
authors.forename: Z
authors.initials: Z
authors.lastname: Szymańska-Toczek
authors.forename: J
authors.initials: J
authors.lastname: Dabek
authors.forename: A
authors.initials: A
authors.lastname: Hrycek
authors.forename: R
authors.initials: R
authors.lastname: Osuch-Jaczewska
authors.forename: M
authors.initials: M
authors.lastname: Baumert
mesh_terms: D000328:Adult; D001724:Birth Weight; D002448:Cell Adhesion; D002585:Cesarean Section; D036861:Delivery, Obstetric; D005260:Female; D005312:Fetal Blood / Q000502:physiology*; D006801:Humans; D007231:Infant, Newborn; D007743:Labor, Obstetric; D007958:Leukocyte Count; D009504:Neutrophils / Q000502:physiology*; D007744:Obstetric Labor Complications; D010587:Phagocytosis; D011247:Pregnancy