Reversal of neurologic disturbances related to high-dose methotrexate by aminophylline.
Peyriere
H
H
Service de Pharmacologie Médicale, Hôpital St. Charles, CHU Montpellier, 34295 Montpellier Cedex 5, France. helenepeyriere@viola.fr
Poiree
M
M
Cociglio
M
M
Margueritte
G
G
Hansel
S
S
Hillaire-Buys
D
D
D000628:Aminophylline / Q000627:therapeutic use*; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D002648:Child; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D020258:Neurotoxicity Syndromes / Q000150:complications / Q000188:drug therapy* / Q000209:etiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy; D051437:Renal Insufficiency / Q000150:complications / Q000209:etiology
D000964:Antimetabolites, Antineoplastic; D000628:Aminophylline; D008727:Methotrexate