title: [Approaches to combined therapy of pulmonary tuberculosis in adolescents excreting drug-resistant Mycobacterium tuberculosis].
abstract: The data are presented on 138 adolescents with active, advanced tuberculosis. M. tuberculosis were detected in the sputum and bronchial lavage of 75(54.3%) adolescents. 32 patients had M. tuberculosis resistant to drugs. 28 untreated patients demonstrated primary drug resistance (37.5%). Intensive combined treatment with consideration of bacterial resistance, administration of reserve drugs, wide spectrum medicines bring about positive results, but in patients with drug resistance positive dynamics is slow.
authors.forename: V A
authors.initials: VA
authors.lastname: Firsova
authors.forename: L I
authors.initials: LI
authors.lastname: Rusakova
authors.forename: Z P
authors.initials: ZP
authors.lastname: Grigor'eva
authors.forename: A P
authors.initials: AP
authors.lastname: Ryzhova
authors.forename: T V
authors.initials: TV
authors.lastname: Iatskova
authors.forename: F G
authors.initials: FG
authors.lastname: Poluéktova
mesh_terms: D000293:Adolescent; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D001980:Bronchi / Q000382:microbiology; D006801:Humans; D008163:Luminescent Measurements; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000302:isolation & purification; D013183:Sputum / Q000382:microbiology; D013997:Time Factors; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents