Gain of virulence caused by insertion of a Pot3 transposon in a Magnaporthe grisea avirulence gene.
The avirulence gene AVR-Pita in Magnaporthe grisea prevents the fungus from infecting rice cultivars carrying the disease resistance gene Pi-ta. Insertion of Pot3 transposon into the promoter of AVR-Pita caused the gain of virulence toward Yashiro-mochi, a rice cultivar containing Pi-ta, which demonstrated the ability of Pot3 to move within the M. grisea genome. The appearance of Pot3 in M. grisea seems to predate the diversification of various host-specific forms of the fungus.
Kang
S
S
DuPont Central Research and Development, Experimental Station, Wilmington, DE 19880-0402, USA. sxk55@psu.edu
Lebrun
M H
MH
Farrall
L
L
Valent
B
B
D001483:Base Sequence; D003062:Codon; D003360:Cosmids; D004251:DNA Transposable Elements; D005800:Genes, Fungal; D020082:Magnaporthe / Q000235:genetics* / Q000472:pathogenicity*; D016254:Mutagenesis, Insertional; D016366:Open Reading Frames; D012275:Oryza / Q000382:microbiology*; D010935:Plant Diseases / Q000382:microbiology; D015183:Restriction Mapping; D014774:Virulence / Q000235:genetics*
D003062:Codon; D004251:DNA Transposable Elements