title: [Prenatal diagnosis of cytomegalovirus infection].
abstract: Prognostic value of markers of cytomegalovirus infection (CMV) in pregnant women for the neonatal status was assessed. Detection of such markers as antiCMV IgM and CMV DNA in cervical secretion by DNA dot-spot hybridization in women with a complicated course of pregnancy indicates a 5.7% risk of delivery of children with stable symptoms. Studies of antibodies to pre-early proteins (IE CMV) showed that antiCMV IgG to IE are more incident in pregnant women than antiCMV IgM; moreover, antiCMV IgG to IE but not antiCMV IgM are detected in umbilical blood. The results of detection of antiCMV IgG and IgM to IE correlated with the clinical characteristics of newborns.
authors.forename: O V
authors.initials: OV
authors.lastname: Ostrovskaia
authors.forename: E P
authors.initials: EP
authors.lastname: Kogut
authors.forename: I P
authors.initials: IP
authors.lastname: Sysoletina
authors.forename: M A
authors.initials: MA
authors.lastname: Vlasova
authors.forename: D Kh
authors.initials: DKh
authors.lastname: Ian
authors.forename: L V
authors.initials: LV
authors.lastname: Maksimchuk
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Vladimirova
mesh_terms: D015415:Biomarkers; D003586:Cytomegalovirus Infections / Q000175:diagnosis*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011296:Prenatal Diagnosis
chemical_list: D015415:Biomarkers