Dexfenfluramine as a mitogen signal via the formation of superoxide anion.
Lee
S L
SL
Pulmonary and Critical Care Division/Tupper Research Institute, Department of Medicine, New England Medical Center/Tufts University School of Medicine, Boston, Massachusetts 02111, USA.
Wang
W W
WW
Fanburg
B L
BL
D000975:Antioxidants / Q000494:pharmacology; D002352:Carrier Proteins / Q000037:antagonists & inhibitors; D002460:Cell Line; D020372:Dexfenfluramine / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005347:Fibroblasts / Q000187:drug effects*; D020935:MAP Kinase Signaling System / Q000502:physiology; D008562:Membrane Glycoproteins / Q000037:antagonists & inhibitors; D026901:Membrane Transport Proteins; D008934:Mitogens / Q000494:pharmacology*; D009419:Nerve Tissue Proteins; D010766:Phosphorylation; D012702:Serotonin Antagonists / Q000494:pharmacology; D050486:Serotonin Plasma Membrane Transport Proteins; D017366:Serotonin Receptor Agonists / Q000494:pharmacology*; D013481:Superoxides / Q000378:metabolism*
D000975:Antioxidants; D002352:Carrier Proteins; D004791:Enzyme Inhibitors; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D008934:Mitogens; D009419:Nerve Tissue Proteins; D012702:Serotonin Antagonists; D050486:Serotonin Plasma Membrane Transport Proteins; D017366:Serotonin Receptor Agonists; D013481:Superoxides; D020372:Dexfenfluramine