title: [Clinical and laboratory diagnosis of Listeria monocytogenes on the basis of own investigations].
abstract: The authors have described the issues surrounding Listeria monocytogenes infection with reference to cases diagnosed and managed during the 5-year period (1995-2000) in the Clinical Department of Neonatal Pathology and Intensive Care of the National Institute of Mother and Child in Warsaw. Four cases of congenital listeriosis have been diagnosed. Some mothers presented with "flu-like" symptoms. All mothers delivered prematurely (29 hbd - 32 hbd). Among the 4 infants the most common clinical features were: perinatal asphyxia, respiratory distress, pathological icterus, haematologic abnormalities. Septicemia occurred in 50% of cases; pneumonia in 100%. Three of them presented skin manifestations; one of the neonates had mucosal abnormalities of the laryngopharynx. Cerebral sonography showed intracranial hemorrhage. One of the infants died within 7 days of birth. The other two neonates developed posthemorrhagic hydrocephalus. Only one infant has normal development. Although listeriosis appears to be not a frequent cause of perinatal infection, clinicians must be aware of Listeria, particularly in gravid patients who present with fever and "flu-like" illness and go into premature labour. Initial therapy implemented in our Department, with ampicillin and aminoglycosides seem to be the most appropriate.
authors.affiliation: Klinika Neonatologii, Instytut Matki i Dziecka w Warszawie, ul. Kasprzaka 17a, 01-211 Warszawa, Polska. imid@imid.med.pl
authors.forename: B
authors.initials: B
authors.lastname: Gierowska-Bogusz
authors.forename: K
authors.initials: K
authors.lastname: Nowicka
authors.forename: H
authors.initials: H
authors.lastname: Drejewicz
mesh_terms: D002543:Cerebral Hemorrhage / Q000209:etiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D008089:Listeria monocytogenes / Q000302:isolation & purification*; D008088:Listeriosis / Q000151:congenital / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D011044:Poland / Q000453:epidemiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*