title: Reduced incidence of Clostridium perfringens-associated lesions and improved performance in broiler chickens treated with normal intestinal bacteria from adult fowl.
abstract: The dosing of young chicks with cultures of normal gut flora has been termed "competitive exclusion" (CE). This study was undertaken to examine, under field conditions, the effect of CE treatment on counts of intestinal Clostridium perfringens (CP) and on the occurrence of CP-associated disease in broiler chickens. A farm having recurrent CP-associated health problems was selected as study site. The study comprised four broiler houses, with one treated and one untreated flock per house. Treated birds were sprayed with the CE product Broilact upon arrival at the farm. All flocks were offered feed containing the ionophorous anticoccidial agent narasin. The feed did not contain growth promoters. Treatment was associated with positive but statistically nonsignificant effects on gut health. Delayed intestinal proliferation of CP and delayed appearance of CP-associated gut lesions were found in CE-treated flocks. This delay was associated with improved production performance at slaughter.
authors.affiliation: National Veterinary Institute, Dep, Oslo, Norway.
authors.forename: M
authors.initials: M
authors.lastname: Kaldhusdal
authors.forename: C
authors.initials: C
authors.lastname: Schneitz
authors.forename: M
authors.initials: M
authors.lastname: Hofshagen
authors.forename: E
authors.initials: E
authors.lastname: Skjerve
mesh_terms: D000821:Animal Feed; D000818:Animals; D000898:Antibiosis; D002645:Chickens; D003015:Clostridium Infections / Q000473:pathology / Q000517:prevention & control / Q000662:veterinary*; D003016:Clostridium perfringens / Q000502:physiology*; D015169:Colony Count, Microbial / Q000662:veterinary; D007422:Intestines / Q000382:microbiology* / Q000469:parasitology; D007476:Ionophores / Q000008:administration & dosage / Q000627:therapeutic use; D008099:Liver / Q000382:microbiology / Q000473:pathology; D008460:Meat / Q000382:microbiology / Q000592:standards; D011201:Poultry Diseases / Q000473:pathology / Q000517:prevention & control*; D011714:Pyrans / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D007476:Ionophores; D011714:Pyrans; C013612:narasin