title: [Hemodynamic effects of STA-MCA anastomosis on patients with occlusion of the main cerebral artery].
abstract: OBJECTIVE
  We studied cerebral circulation in patients with occlusion of the main cerebral artery and investigated the efficacy of STA-MCA anastomosis.
  
  
  METHODS
  Thirty-six patients with occlusion of the main cerebral artery were studied. Twenty-three patients had occlusion of the internal carotid artery and 13 had occlusion of the middle cerebral artery. The mean age was 62 years. Cerebral blood flow (CBF) was measured in all patients and cerebrovascular reactivity (CVR) was examined in 11 patients by xenon enhanced CT. Intraoperatively, cortical arterial pressure and anastomotic flow were measured.
  
  
  RESULTS
  There was no perioperative mortality or morbidity. There was no ipsilateral stroke recurrence during the follow-up period averaging 35.1 months. Patency of the anastomosis was verified in 91% of the patients by magnetic resonance angiography. Twenty-three (64%) patients showed decreased CBF before the operation and 57% of these patients showed improvement to the normal range after STA-MCA anastomosis. All of the eight patients with decreased CVR showed improvement after the operation. Anastomotic flow correlated significantly with the cortical arterial pressure.
  
  
  CONCLUSIONS
  STA-MCA anastomosis could improve cerebral circulation of patients with low CBF or low CVR due to occlusion of the main cerebral arterial. It was concluded that STA-MCA anastomosis may contribute to the reduction of stroke recurrence, if perioperative complications are reduced.
authors.affiliation: Department of Neurosurgery, Chugoku Rosai Hospital, 1-5-1 Hirotagaya, Kure 737-0193, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yamane
authors.forename: T
authors.initials: T
authors.lastname: Shima
authors.forename: M
authors.initials: M
authors.lastname: Nishida
authors.forename: T
authors.initials: T
authors.lastname: Hatayama
authors.forename: C
authors.initials: C
authors.lastname: Yamanaka
authors.forename: A
authors.initials: A
authors.lastname: Toyota
authors.forename: K
authors.initials: K
authors.lastname: Hiramatsu
authors.forename: S
authors.initials: S
authors.lastname: Ishino
authors.forename: Y
authors.initials: Y
authors.lastname: Okada
mesh_terms: D000368:Aged; D001157:Arterial Occlusive Diseases / Q000503:physiopathology / Q000601:surgery*; D002340:Carotid Artery Diseases / Q000503:physiopathology / Q000601:surgery*; D002343:Carotid Artery, Internal / Q000601:surgery; D002548:Cerebral Revascularization / Q000379:methods*; D002560:Cerebrovascular Circulation; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000503:physiopathology / Q000601:surgery*; D008875:Middle Aged; D020521:Stroke / Q000517:prevention & control