title: Allopurinol hypersensitivity syndrome associated with systemic cytomegalovirus infection and systemic bacteremia.
abstract: A 43-year-old man developed fever, skin rash, eosinophillia, and severe renal and liver dysfunction following treatment with allopurinol. The patient died after 3 months of hospitalization. Autopsy revealed systemic cytomegalovirus infection and bacteremia.
authors.affiliation: Department of Internal Medicine, Ishinomaki Red Cross Hospital.
authors.forename: M
authors.initials: M
authors.lastname: Arakawa
authors.forename: Y
authors.initials: Y
authors.lastname: Kakuto
authors.forename: K
authors.initials: K
authors.lastname: Ichikawa
authors.forename: J
authors.initials: J
authors.lastname: Chiba
authors.forename: N
authors.initials: N
authors.lastname: Tabata
authors.forename: Y
authors.initials: Y
authors.lastname: Sasaki
mesh_terms: D000328:Adult; D000493:Allopurinol / Q000009:adverse effects*; D000900:Anti-Bacterial Agents; D000998:Antiviral Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003586:Cytomegalovirus Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D004342:Drug Hypersensitivity / Q000150:complications*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D015774:Ganciclovir / Q000627:therapeutic use; D006074:Gout Suppressants / Q000009:adverse effects; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male; D012867:Skin / Q000098:blood supply / Q000473:pathology; D012883:Skin Ulcer / Q000473:pathology / Q000821:virology
chemical_list: D000900:Anti-Bacterial Agents; D000998:Antiviral Agents; D006074:Gout Suppressants; D000493:Allopurinol; D015774:Ganciclovir