title: Latanoprost and the ibopamine test: a year's experience.
abstract: We report here the results obtained in a group of 52 eyes affected by open-angle Glaucoma (OAG), whose intraocular pressure (IOP) was inadequately controlled by two drugs of different pharmacological categories, into which there was introduced Latanoprost, both in place of one of the two drugs and in addition to the preceding therapy. The ocular hypotensive effect was good (21.74%). The ibopamine provocative test, carried out before the Latanoprost administration, and at 3 and 6 months into treatment gave evidence that outflow pathway compromission was uninfluenced by the drug.
authors.affiliation: Institute of Ophthalmology, La Sapienza University, Rome.
authors.forename: J
authors.initials: J
authors.lastname: Pecori Giraldi
authors.forename: A
authors.initials: A
authors.lastname: Mollicone
authors.forename: D
authors.initials: D
authors.lastname: Seguto
authors.forename: L
authors.initials: L
authors.lastname: Simeone
authors.forename: F
authors.initials: F
authors.lastname: Zaccara
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001082:Aqueous Humor / Q000187:drug effects* / Q000378:metabolism; D003846:Deoxyepinephrine / Q000031:analogs & derivatives*; D018491:Dopamine Agonists; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D000077338:Latanoprost; D008297:Male; D011461:Prostaglandins F, Synthetic / Q000627:therapeutic use*
chemical_list: D000959:Antihypertensive Agents; D018491:Dopamine Agonists; D011461:Prostaglandins F, Synthetic; D000077338:Latanoprost; C023487:ibopamine; D003846:Deoxyepinephrine