title: Iron status and indicators of human immunodeficiency virus disease severity among pregnant women in Malawi.
abstract: The relationships among hemoglobin, ferritin, and transferrin receptor levels and 2 markers of human immunodeficiency virus (HIV) disease severity--HIV load and CD4(+) lymphocyte count--were characterized among 483 pregnant women in Malawi, Africa. The only significant correlation was an inverse correlation between hemoglobin level and plasma HIV load (r=-.104; P<.03). The prevalence of iron deficiency anemia was not significantly different across quartiles of HIV load or CD4(+) lymphocyte count. In contrast to previous studies, these data suggest that iron status is not related to markers of HIV disease severity in pregnant women in Africa.
authors.affiliation: Department of Ophthalmology, Johns Hopkins University Schools of Medicine and Hygiene and Public Health, Baltimore, MD 21205, USA. rdsemba@jhmi.edu
authors.forename: R D
authors.initials: RD
authors.lastname: Semba
authors.forename: T E
authors.initials: TE
authors.lastname: Taha
authors.forename: N
authors.initials: N
authors.lastname: Kumwenda
authors.forename: L
authors.initials: L
authors.lastname: Mtimavalye
authors.forename: R
authors.initials: R
authors.lastname: Broadhead
authors.forename: P G
authors.initials: PG
authors.lastname: Miotti
authors.forename: J D
authors.initials: JD
authors.lastname: Chiphangwi
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000175:diagnosis*; D018791:CD4 Lymphocyte Count; D018450:Disease Progression; D005260:Female; D006678:HIV / Q000502:physiology; D015658:HIV Infections / Q000097:blood / Q000503:physiopathology* / Q000821:virology; D006801:Humans; D007501:Iron / Q000097:blood*; D008295:Malawi; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood / Q000503:physiopathology* / Q000821:virology; D012720:Severity of Illness Index; D019562:Viral Load
chemical_list: D007501:Iron