title: Treatment of a human transosseous mandibular defect by guided bone regeneration.
abstract: The treatment of through-and-through human periapical lesions by barrier membrane techniques has not been reported in the periodontal literature. However, periodontists frequently perform this treatment. The authors present a case that demonstrates radiopacity after regeneration surgery of a human periapical transosseous mandibular defect, suggesting local bone regeneration. The surgical technique performed in this case was based on the principles of guided bone regeneration using a demineralized freeze-dried bone membrane (DFDBM). The bone membrane acted as an efficient barrier that excluded the nonosteogenic tissue. Radiographic findings demonstrated bone fill after 8 months.
authors.affiliation: Department of Periodontology, Fluminense Federal University, School of Dentistry, Rio de Janeiro, Brazil. barbozae@uol.com.br
authors.forename: E P
authors.initials: EP
authors.lastname: Barboza
authors.forename: C E
authors.initials: CE
authors.lastname: Lugão
mesh_terms: D001861:Bone Regeneration; D018786:Bone Substitutes / Q000627:therapeutic use; D016025:Bone Transplantation; D003648:Decalcification Technique; D005260:Female; D005612:Freeze Drying; D048091:Guided Tissue Regeneration / Q000379:methods*; D006801:Humans; D008336:Mandibular Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D008567:Membranes, Artificial; D008875:Middle Aged; D010483:Periapical Diseases / Q000000981:diagnostic imaging / Q000601:surgery; D011859:Radiography; D014021:Tissue Preservation
chemical_list: D018786:Bone Substitutes; D008567:Membranes, Artificial