title: [Predictive value of non-automated spermatic parameters and automated kinetic parameters on cleavage rate in fertilization in vitro].
abstract: The aim of this work was to determine retrospectively in 114 couples the predictive value of semen analysis for the in vitro fertilization (IVF) outcome when sperm evaluation before IVF was assessed by either conventional parameters or a Hamilton-Thorne automated motility analyser. A backward logistic regression analysis was used to study the relative contribution of each conventional or computerized parameter. Computerized sperm values were the worst index for predicting oocyte fertilization. However a tight relationship between morphology and cleavage ratio was observed. Using ROC analysis, under a 18% threshold, cleavage failure was noted in 71% of couples undergoing an IVF program. This study indicates that morphology is the best parameter for predicting cleavage failure.
authors.affiliation: CECOS-spermiologie, département génétique et reproduction (Pr. P. Leymarie), GHU Côte de Nacre, 14033 Caen, France.
authors.forename: A
authors.initials: A
authors.lastname: Chocat
authors.forename: C
authors.initials: C
authors.lastname: Creveuil
authors.forename: I
authors.initials: I
authors.lastname: Galeraud-Denis
authors.forename: D
authors.initials: D
authors.lastname: Herlicoviez
authors.forename: M
authors.initials: M
authors.lastname: Herlicoviez
authors.forename: A
authors.initials: A
authors.lastname: Sauvalle
mesh_terms: D000328:Adult; D001322:Autoanalysis; D002970:Cleavage Stage, Ovum; D003201:Computers; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012661:Semen / Q000502:physiology*; D013081:Sperm Motility; D013094:Spermatozoa / Q000002:abnormalities; D016896:Treatment Outcome