title: Simultaneous determination of imazalil and its major metabolite in citrus fruit by solid-phase extraction and capillary gas chromatography with electron capture detection.
abstract: A method was developed for the simultaneous determination of imazalil and its major metabolite, R 14821, in citrus fruit. This method (designated the SPE method) is based on solid-phase extraction (SPE) and capillary gas chromatography (GC) with electron-capture detection (ECD). The SPE method is highly sensitive for both compounds (limit of detection for each: 0.001 microg/g) and is less time consuming than the previously reported method based on repeated liquid-liquid partitioning and GC-ECD. Recoveries for 3 levels of fortification (0.02, 0.2, and 2.5 microg/g) from satsuma mandarins ranged from 94.3 to 96.5% for imazalil and from 93.9 to 96.3 % for R 14821, with coefficients of variation (CVs) ranging from 3.1 to 6.3% for imazalil and from 4.5 to 5.6% for R 14821. Average residual levels found in grapefruit, oranges, and lemons by the SPE method and the previously reported method, and the corresponding CVs, were similar.
authors.affiliation: Osaka Prefectural Institute of Public Health, Laboratory of Food Chemistry, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
mesh_terms: D002849:Chromatography, Gas; D002957:Citrus / Q000737:chemistry*; D004563:Electrochemistry; D005659:Fungicides, Industrial / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D007093:Imidazoles / Q000032:analysis*; D007202:Indicators and Reagents; D012996:Solutions
chemical_list: D005659:Fungicides, Industrial; D007093:Imidazoles; D007202:Indicators and Reagents; D012996:Solutions; C017435:enilconazole