Aneurysm of the ductus arteriosus in a neonate with 13q-deletion.
Aneurysm of the ductus arteriosus is a rare abnormality for which different ways of pathogenesis are described. We report the case of a fatal thrombosis of an aneurysm of the ductus arteriosus in an infant presenting feeding difficulties and a mild dysmorphic facies. Karyotype analysis revealed a de novo chromosomal deletion 46,XY, del (13)(q12.3,q22.3). To the best of our knowledge, this is the first case of an aneurysm of the ductus arteriosus associated with a chromosomal aberration.
Naulaers
G
G
Department of Paediatrics, UZ Gasthuisberg, Leuven, Belgium.
Devriendt
K
K
Moerman
P
P
Gillis
P
P
Vanhole
C
C
Devlieger
H
H
D000783:Aneurysm / Q000150:complications / Q000151:congenital* / Q000235:genetics / Q000473:pathology; D002872:Chromosome Deletion; D002882:Chromosomes, Human, Pair 13; D004373:Ductus Arteriosus; D017809:Fatal Outcome; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D013927:Thrombosis / Q000209:etiology* / Q000473:pathology