Accuracy of histologic grading of synovial inflammation in temporomandibular joints with internal derangement using Gynther's system.
OBJECTIVE
The purpose of this study was to evaluate the accuracy of the system by Gynther et al (J Oral Maxillofac Surg 56:1281, 1998) for histologic grading of synovial inflammation in the temporomandibular joint (TMJ) in arthroscopically obtained synovial biopsy specimens.


METHODS
Thirty-three human TMJ synovial biopsy specimens from patients with internal derangement of the TMJ were evaluated using the system of Gynther et al. The results were compared statistically with the intensity of synovitis seen arthroscopically using Spearman ranked correlation coefficient.


RESULTS
In 2 of the 3 parameters tested, a statistically significant correlation was found between the histologic findings by the system of Gynther et al and arthroscopic findings using the scale of Murakami et al (J Oral Maxillofac Surg 49:1159, 1991)


CONCLUSIONS
These results suggest that histologic grading of synovial inflammation by the system of Gynther et al has considerable accuracy. However, more investigations are necessary to confirm the results.
Suzuki
T
T
Kanazawa Medical University, Department of Oral and Maxillofacial Surgery, 1. Daigaku, Uchinada-machi, Kahoku-gun, Ishikawa, 920-0293, Japan. suzukig3@kanazawa-med.ac.jp
Segami
N
N
Sato
J
J
Nojima
T
T
D000293:Adolescent; D000328:Adult; D001182:Arthroscopy; D001706:Biopsy; D005260:Female; D006801:Humans; D004204:Joint Dislocations / Q000473:pathology; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D013585:Synovitis / Q000473:pathology*; D013705:Temporomandibular Joint Disorders / Q000473:pathology*