Magnetization transfer in MRI: a review.
This review describes magnetization transfer (MT) contrast in magnetic resonance imaging. A qualitative description of how MT works is provided along with experimental evidence that leads to a quantitative model for MT in tissues. The implementation of MT saturation in imaging sequences and the interpretation of the MT-induced signal change in terms of exchange processes and direct effects are presented. Finally, highlights of clinical uses of MT are outlined and future directions for investigation proposed.
Henkelman
R M
RM
Department of Medical Biophysics University of Toronto, Toronto, Canada. mark.henkelman@swchsc.on.ca
Stanisz
G J
GJ
Graham
S J
SJ
D055592:Biophysical Phenomena; D001703:Biophysics; D006801:Humans; D046911:Macromolecular Substances; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008280:Magnetics; D014867:Water
D046911:Macromolecular Substances; D014867:Water