SHV-type extended-spectrum beta-lactamase in a Shigella flexneri clinical isolate.
A Shigella flexneri isolate resistant to oxyimino-cephalosporins was recovered from a stool sample of a 16 month-old Algerian child hospitalized in Paris, France. This isolate harboured an SHV-2 beta-lactamase gene located on a c. 80 kb self-transferable plasmid. This is the first report of an Ambler class A extended-spectrum beta-lactamase from Shigella spp.
Fortineau
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N
Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre, France. nicolas.fortineau@bct.ap-hop-paris.fr
Naas
T
T
Gaillot
O
O
Nordmann
P
P
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001483:Base Sequence; D004269:DNA, Bacterial / Q000032:analysis; D006801:Humans; D007223:Infant; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D012763:Shigella flexneri / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; C062760:beta-lactamase SHV-2; D001618:beta-Lactamases