Pharmacologic treatments for the nicotine dependent smoker.
OBJECTIVE
To explore the biology of nicotine addiction and to investigate the latest pharmacological treatments for nicotine dependence.


METHODS
Explore the research literature for treating nicotine dependence.


RESULTS
Nicotine is an additive drug and the most effective methods for treating dependence are nicotine replacement therapy (NRT) and bupropion SR.


CONCLUSIONS
The best available treatments for nicotine dependence are pharmacological adjuncts; specifically, NRT and bupropion SR when combined with behavioral counseling.
Glover
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ED
Tobacco Research Center, West Virginia University School of Medicine, Morgantown 26506-9300, USA. eglover@hsc.wvu.edu
Glover
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PN
D016642:Bupropion / Q000008:administration & dosage*; D018765:Dopamine Uptake Inhibitors / Q000008:administration & dosage*; D006801:Humans; D009538:Nicotine / Q000008:administration & dosage*; D012907:Smoking / Q000188:drug therapy / Q000378:metabolism; D013375:Substance Withdrawal Syndrome; D014029:Tobacco Use Disorder / Q000188:drug therapy* / Q000378:metabolism; D014481:United States
D018765:Dopamine Uptake Inhibitors; D016642:Bupropion; D009538:Nicotine