[The in-vitro effect of constant and pulsating magnetic field on immunocompetent blood cells of hematologic patients].
Immunologic characteristics were studied in 103 patients with multiple myeloma, acute leukemia, chronic lymphocytic leukemia and non-Hodgkin's disease following in vitro exposure of blood to a low-intensity static field (SF) and alternating field (AF) or pulsating magnetic field (PF). In a SF-AF study of multiple myeloma, a 30 min exposure had a positive effect on expression of tumor cells and T-cell markers and stimulated the regulatory function of T-lymphocytes. With SF-AF and PF application alternating, the expression of both +CD3 and +CD4 and the +CD3/+CD4 ratio increased suggesting the lowering of immunological deficiency. In acute leukemia, a combined application of the magnetic fields had an effect on the helper activity of the T-lymphocyte subpopulation. The phagocytic activity of leukocytes increased significantly while their digestive ability rose to a moderate degree.
Bessmel'tsev
S S
SS
Russian Research Institute of Hematology and Transfusiology, St. Petersburg.
Abdulkadyrov
K M
KM
Gonchar
V A
VA
Lavrushina
T S
TS
D000208:Acute Disease; D015703:Antigens, CD / Q000276:immunology; D016022:Case-Control Studies; D004574:Electromagnetic Fields; D006402:Hematologic Diseases / Q000628:therapy*; D006801:Humans; D066298:In Vitro Techniques; D007938:Leukemia / Q000628:therapy; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000628:therapy; D007962:Leukocytes / Q000276:immunology*; D016131:Lymphocyte Subsets / Q000276:immunology; D008228:Lymphoma, Non-Hodgkin / Q000628:therapy; D009101:Multiple Myeloma / Q000628:therapy; D013601:T-Lymphocytes / Q000276:immunology*
D015703:Antigens, CD