title: How are peroxisomes formed? The role of the endoplasmic reticulum and peroxins.
abstract: Recent data from studies of peroxisome assembly and the subcellular sorting of peroxisomal matrix and membrane proteins have led to an expansion of the 'growth and division' and 'endoplasmic reticulum-vesiculation' models of peroxisome biogenesis into a more flexible, unified model. Within this context, we discuss the proposed role for the endoplasmic reticulum in the formation of preperoxisomes and the potential for 15 Arabidopsis peroxin homologs to function in the biogenesis of peroxisomes in plant cells.
authors.affiliation: Dept Botany, University of Guelph, N1G 2W1., Guelph, Ontario, Canada. rtmullen@uoguelph.ca
authors.forename: R T
authors.initials: RT
authors.lastname: Mullen
authors.forename: C R
authors.initials: CR
authors.lastname: Flynn
authors.forename: R N
authors.initials: RN
authors.lastname: Trelease
mesh_terms: D060387:Ascorbate Peroxidases; D001692:Biological Transport; D004721:Endoplasmic Reticulum / Q000235:genetics / Q000378:metabolism*; D017343:Genes, Plant / Q000502:physiology; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism*; D008954:Models, Biological; D010544:Peroxidases / Q000378:metabolism; D000074437:Peroxisomal Targeting Signal 2 Receptor; D000074435:Peroxisome-Targeting Signal 1 Receptor; D020675:Peroxisomes / Q000235:genetics / Q000378:metabolism*; D010940:Plant Proteins; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism; D017385:Sequence Homology; D015398:Signal Transduction; D015003:Yeasts / Q000378:metabolism
chemical_list: D008565:Membrane Proteins; D000074437:Peroxisomal Targeting Signal 2 Receptor; D000074435:Peroxisome-Targeting Signal 1 Receptor; D010940:Plant Proteins; D018160:Receptors, Cytoplasmic and Nuclear; D010544:Peroxidases; D060387:Ascorbate Peroxidases