title: [The change of salivary beta 2-microglobulin concentration in normal adults].
abstract: OBJECTIVE
  To understand the influence of various physiological factors on the concentration of beta 2-microglobulin in saliva.
  
  
  METHODS
  We measured salivary beta 2-microglobulin concentration in 200 normal adults, from 21 year-old to 70 year-old, by means of radioactive immunoassay method.
  
  
  RESULTS
  We found, that there was no significant difference between males and females in salivary beta 2-m concentration, and salivary beta 2-m concentration was more significantly elevated in the adults above 50 year-old, compared with the adults from 21 year-old to 50 year-old. We also found, that there was no significant correlation between salivary beta 2-m concentration and serum beta 2-m concentration.
  
  
  CONCLUSIONS
  Our results suggested, that beta 2-m in saliva may be produced in oral cavity and salivary glands, and measurement of salivary beta 2-m concentration may offer a valuable method to diagnose lymphocytic infiltration disease in oral cavity or salivary glands.
authors.affiliation: PUMC Hospital, CAMS and PUMC, Beijing 100730.
authors.forename: Y
authors.initials: Y
authors.lastname: Bu
authors.forename: D
authors.initials: D
authors.lastname: Du
authors.forename: Y
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D012016:Reference Values; D012463:Saliva / Q000737:chemistry*; D012737:Sex Factors; D001613:beta 2-Microglobulin / Q000032:analysis*
chemical_list: D001613:beta 2-Microglobulin