title: Amine and tin fluoride inhibition of Streptococcus sanguis adhesion under continuous flow.
abstract: This study evaluated the ability of topically applied amine fluoride (AmF) and AmF-tin fluoride to inhibit the adhesion of Streptococcus sanguis within a parallel plate flow cell system. One of three AmF compounds and two tin fluoride preparations significantly reduced the net bacterial adhesion to conditioned glass over a 1-h period. Tin(IV) fluoride inhibited S. sanguis adhesion to the greatest extent, and this was shown to be dependent on the formation of the conditioning film prior to agent application.
authors.affiliation: Department of Microbiology, Eastman Dental Institute, University College London, United Kingdom.
authors.forename: J V
authors.initials: JV
authors.lastname: Embleton
authors.forename: H N
authors.initials: HN
authors.lastname: Newman
authors.forename: M
authors.initials: M
authors.lastname: Wilson
mesh_terms: D001422:Bacterial Adhesion / Q000187:drug effects*; D002327:Cariostatic Agents / Q000494:pharmacology*; D005459:Fluorides / Q000494:pharmacology; D005460:Fluorides, Topical / Q000494:pharmacology*; D005898:Glass; D006801:Humans; D012212:Rheology; D012463:Saliva / Q000502:physiology; D012710:Serum Albumin, Bovine / Q000502:physiology; D018709:Statistics, Nonparametric; D013298:Streptococcus sanguis / Q000187:drug effects*; D013499:Surface Properties; D014002:Tin Fluorides / Q000494:pharmacology*; D014867:Water; D017967:Zinc Compounds / Q000494:pharmacology
chemical_list: D002327:Cariostatic Agents; D005460:Fluorides, Topical; D014002:Tin Fluorides; D017967:Zinc Compounds; C094808:amine fluoride solution; D014867:Water; D012710:Serum Albumin, Bovine; C038904:zinc fluoride; D005459:Fluorides