title: Micropatterning of biomedical polymer surfaces by novel UV polymerization techniques.
abstract: The "living" radical polymerization with an iniferter was used to create micropatterned biomedical surfaces. Novel, photosensitive biomedical polymers were created by the incorporation of dithiocarbamate groups from iniferters. A second monomer layer was then irradiated onto the photosensitive polymer substrate created with the iniferter to form a copolymer. Patterns were created on the films by application of modified microfabrication-based photolithographic techniques. The technique was used to create patterns with depths from 5 to 80 microm. In addition, various polymers were incorporated, including polyethylene glycol methacrylates, styrene, and methacrylic acid, to synthesize regions with different physico-chemical properties. Applications include novel surfaces for biosensors and biomaterials for the selective adhesion of cells and proteins.
authors.affiliation: School of Chemical Engineering, 1283 Chemical Engineering Building, Purdue University, West Lafayette, IN 47907-1283, USA.
authors.forename: J H
authors.initials: JH
authors.lastname: Ward
authors.forename: R
authors.initials: R
authors.lastname: Bashir
authors.forename: N A
authors.initials: NA
authors.lastname: Peppas
mesh_terms: D001672:Biocompatible Materials; D019281:Dimerization; D011108:Polymers; D013499:Surface Properties; D014466:Ultraviolet Rays
chemical_list: D001672:Biocompatible Materials; D011108:Polymers