title: Development of a water-soluble preparation of emamectin benzoate and its preventative effect against the wilting of pot-grown pine trees inoculated with the pine wood nematode, Bursaphelenchus xylophilus.
abstract: Water-soluble preparations have been investigated to develop a trunk injection agent based on the poorly water-soluble anti-nematode emamectin benzoate. Following tests on the phytotoxicity of some solvents and solubilizers and demonstration of the ability of some solubilizers to dissolve emamectin benzoate in water, acetone + methanol was selected as the solvent and Polysorbate 80 as the solubilizer. This water-soluble preparation of emamectin benzoate prevented the wilting of pot-grown 4-year-old trees of the Japanese black pine, Pinus thunbergii, artificially inoculated with the pine wood nematode, Bursaphelenchus xylophilus, at a dose of 20 g emamectin benzoate per cubic metre of pine tree.
authors.affiliation: Development Department, Izutsuya Chemical Industry Co Ltd, 1-11-30 Hanazono, Kumamoto 860-0072, Japan. izuchem@ruby.ocn.ne.jp
authors.forename: K
authors.initials: K
authors.lastname: Takai
authors.forename: T
authors.initials: T
authors.lastname: Soejima
authors.forename: T
authors.initials: T
authors.lastname: Suzuki
authors.forename: K
authors.initials: K
authors.lastname: Kawazu
mesh_terms: D000818:Animals; D007267:Injections; D007306:Insecticides / Q000737:chemistry; D007559:Ivermectin / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D009348:Nematoda; D010935:Plant Diseases; D018547:Plant Stems; D011136:Polysorbates / Q000009:adverse effects; D012995:Solubility; D012997:Solvents / Q000009:adverse effects; D014197:Trees
chemical_list: D007306:Insecticides; D011136:Polysorbates; D012997:Solvents; D007559:Ivermectin; C108024:emamectin benzoate