title: Atypical depression with hypomanic symptoms.
abstract: BACKGROUND
  Depressive mixed states (major depressive episodes with some hypomanic symptoms) (DMS) are not classified in DSM-IV and are understudied. The aims of this study were to find the prevalence and clinical features of DMS in atypical depression.
  
  
  METHODS
  A total of 87 bipolar II and unipolar depressed outpatients were interviewed within the DSM-IV Structured Clinical Interview.
  
  
  RESULTS
  More than two hypomanic symptoms were present in 50.0% of the atypical and 20.3% of the non-atypical depression cases (P=0.006). DMS mainly included irritable mood, distractibility, racing thoughts, and increased talking.
  
  
  CONCLUSIONS
  There was a single interviewer, and it was a non-blind, cross-sectional assessment, with bipolar II reliability.
  
  
  CONCLUSIONS
  Findings have treatment implications, as antidepressants may worsen DMS, and mood stabilizers may improve it.
authors.affiliation: Department of Psychiatry, National Health Service (A.USL), P. Solieri 4, 47100 Forlì, Italy. f.benazzi@fo.nettuno.it
authors.forename: F
authors.initials: F
authors.lastname: Benazzi
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects / Q000494:pharmacology; D001714:Bipolar Disorder / Q000523:psychology*; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D000928:Antidepressive Agents