title: The leser-trelat sign in association with carcinoma of the ampulla of Vater.
abstract: A 45-yr-old woman was admitted to our hospital for surgical treatment of obstructive jaundice. She was treated by a standard pancreatoduodenectomy (Whipple procedure). The biopsy of the specimen disclosed an adenocarcinoma of the ampulla of Vater. Six months before the appearance of the obstructive jaundice, she noted a sudden onset of many seborrheic keratoses on the upper part of her trunk and upper extremities. This, to our knowledge, is the first case of Leser-Trelat sign associated with adenocarcinoma of the ampulla of Vater.
authors.affiliation: Second Surgical Department, Evangelismos Hospital, Athens, Greece.
authors.forename: S
authors.initials: S
authors.lastname: Klimopoulos
authors.forename: C
authors.initials: C
authors.lastname: Kounoudes
authors.forename: C
authors.initials: C
authors.lastname: Pantelidaki
authors.forename: K
authors.initials: K
authors.lastname: Skrepetou
authors.forename: M
authors.initials: M
authors.lastname: Papoudos
authors.forename: H
authors.initials: H
authors.lastname: Katsoulis
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000601:surgery; D014670:Ampulla of Vater; D003138:Common Bile Duct Neoplasms / Q000150:complications* / Q000601:surgery; D005260:Female; D006801:Humans; D017492:Keratosis, Seborrheic / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D016577:Pancreaticoduodenectomy