The potential of alkaloids in drug discovery.
Alkaloids are an important group of diversely distributed, chemically, biologically and commercially significant natural products. This article suggests why now, with the presently available technology, and the remaining biome available and reasonably accessible, is an opportune moment to consciously focus on the discovery of further alkaloids with pharmacophoric utility.
Cordell
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GA
Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA. cordell@uic.edu
Quinn-Beattie
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ML
Farnsworth
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NR
D000470:Alkaloids / Q000627:therapeutic use*; D004358:Drug Therapy / Q000639:trends*; D006801:Humans; D010946:Plants, Medicinal
D000470:Alkaloids