[Clinical study on treatment of moderate and advanced stage cancers by Bailong Tablets combined with chemotherapy].
OBJECTIVE
To assess the effects and mechanism of Bailong Tablet combined chemotherapy treatment.


METHODS
The test group, 41 cancer patients of moderate and advanced stage treated by chemotherapy plus Bailong tablet, and the control group, 22 cancer patients treated by chemotherapy alone. Observe the chemotherapy complete rates (CCR) and the immunological function of the cell in the two groups.


RESULTS
The CCR in the test group (92.6%) were higher than that of the control group (77.2%, P < 0.05). However, the toxic side-effect caused by chemotherapy in the test group were lower than that in the control group (P < 0.05). CD3 and the ratio of CD4/CD8 were obviously raised in the test group. The results indicates that the Bailong Tablets had the effects of regulating the immunological function of the T-cell.


CONCLUSIONS
Bailong tablet could enhance the efficacy and reduce the toxic side-effect of chemotherapy. Modulation of the cell immunological function is possibly its mechanism.
Zhang
X
X
School of Oncology, Beijing Medical University, Beijing Institute for Cancer Research(100036).
Liu
S
S
Liang
Y
Y
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D016516:CD4-CD8 Ratio; D003110:Colonic Neoplasms / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013607:Tablets
D000276:Adjuvants, Immunologic; D004365:Drugs, Chinese Herbal; D013607:Tablets