Management of a patient with advanced AIDS and toxic epidermal necrolysis using human growth hormone and G-CSF.
Toxic epidermal necrolysis (TEN) is a serious drug reaction that is occurring with increased frequency among those affected with HIV and AIDS. It carries a grave prognosis for those with advanced AIDS and massive skin involvement. We report a severe case of TEN treated with wound care, intravenous nutrition, human growth hormone (hgh), and granulocyte colony-stimulating factor (G-CSF).
Bae
R J
RJ
Harvard Medical School, Boston, Massachusetts, USA.
Orgill
D P
DP
DeBiasse
M A
MA
Demling
R
R
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D017809:Fatal Outcome; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D019382:Human Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010288:Parenteral Nutrition; D013262:Stevens-Johnson Syndrome / Q000209:etiology* / Q000628:therapy*
D019382:Human Growth Hormone; D016179:Granulocyte Colony-Stimulating Factor