Long-term graft survival after urological complications of 695 kidney transplantations.
OBJECTIVE
We ascertain the incidence, management and long-term outcome of early urological complications requiring surgical exploration in kidney transplantation.


METHODS
Data of 695 consecutive kidney transplantations performed between January 1985 and January 1997 were assessed in regard to urological complications that occurred within 1 year after transplant. A computerized database was used to analyze graft recipient characteristics, the implantation procedure, complications and outcome in select patients and all those who underwent transplant during the same period. In the noncomplication group sufficient data for evaluation was available for 556 patients. We performed the Cox proportional hazards analysis with overall graft failure, graft failure or death as end points of observation.


RESULTS
Overall, 42 (6.0%) patients required revision of vesicoureteral anastomosis. Complications were identified after a median of 6 days (range 0 to 135). The primary reconstruction technique was extravesical in 64% and transvesical in 33% of patients, including 1 that involved ureteral Bricker anastomosis. Obstruction and/or leakage at vesicoureteral anastomosis accounted for 69% of urological complications. Revision was performed with a number of different reconstruction techniques. A second revision was required in 16.7%. Mean followup after primary transplant was 9.1 years (range 3.2 to 15). Multivariate analysis showed that surgical treatment of urological complication during year 1 after kidney transplantation did not increase the risk of overall graft failure, graft failure or death.


CONCLUSIONS
Our results indicate that long-term graft survival is not affected by a surgically treated urological complication.
van Roijen
J H
JH
Department of Urology, University Hospital Rotterdam-Dijkzigt, Rotterdam, The Netherlands.
Kirkels
W J
WJ
Zietse
R
R
Roodnat
J I
JI
Weimar
W
W
Ijzermans
J N
JN
D000328:Adult; D003251:Constriction, Pathologic; D005260:Female; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D019651:Plastic Surgery Procedures; D014513:Ureter / Q000473:pathology; D014515:Ureteral Diseases / Q000209:etiology; D014570:Urologic Diseases / Q000209:etiology*