Quantitative morphometry--an easy and inexpensive method for comparative studies of antigen expression during development.
The morphometric studies due to the development of computerized techniques became a very suitable tool for quantitative analysis. In the present paper we describe an easy and relatively inexpensive method useful for comparative studies on changes of expression of examined molecules during development of tissue. We used with a success this method for studies on the expression of CD31 adhesion molecule during the fetal and newborn lung development. We found that expression of CD31 is regulated during the perinatal period. It might be related to the dynamic changes in developing vascular bed in rat lung.
Marszałek
A
A
Department of Pathomorphology, University of Medical Sciences, Poznań, Poland. andrzej@oita-med.ac.jp
Wasowicz
M
M
Biczysko
W
W
D000818:Animals; D000831:Animals, Newborn; D005260:Female; D007150:Immunohistochemistry; D008168:Lung / Q000196:embryology* / Q000378:metabolism*; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000096:biosynthesis*; D011247:Pregnancy; D051381:Rats; D013194:Staining and Labeling
D019408:Platelet Endothelial Cell Adhesion Molecule-1