Mycophenolate mofetil interferes with interferon gamma production in T-cell activation models.
Izeradjene
K
K
Immunopharmacology Unit, INSERM U. 503, Hôpital E. Herriot, Lyon, France.
Quemeneur
L
L
Michallet
M C
MC
Bonnefoy-Berard
N
N
Revillard
J P
JP
D000818:Animals; D000961:Antilymphocyte Serum / Q000494:pharmacology; D002478:Cells, Cultured; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007371:Interferon-gamma / Q000096:biosynthesis* / Q000097:blood; D007376:Interleukin-2 / Q000096:biosynthesis; D008213:Lymphocyte Activation / Q000187:drug effects*; D051379:Mice; D008807:Mice, Inbred BALB C; D016853:Muromonab-CD3 / Q000494:pharmacology; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000494:pharmacology*; D010835:Phytohemagglutinins; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D000961:Antilymphocyte Serum; D007166:Immunosuppressive Agents; D007376:Interleukin-2; D016853:Muromonab-CD3; D010835:Phytohemagglutinins; D014409:Tumor Necrosis Factor-alpha; C028784:phytohemagglutinin-P; D007371:Interferon-gamma; D009173:Mycophenolic Acid