title: Low-power diode laser stimulation of surgical osteochondral defects: results after 24 weeks.
abstract: The purpose of this study was to evaluate osteochondral lesions of the knee, treated intraoperatively with low-power laser stimulation, and assess results at 24 weeks. Surgery was performed under general anesthesia on six rabbits; a bilateral osteochondral lesion was created in the femoral medial condyles with a drill. All of the left lesions underwent immediate stimulation using the diode Ga-Al-As laser (780nm), whereas the right knees were left untreated as control group. After 24 weeks, the explants from the femoral condyles, either treated employing laser energy or left untreated, were examined histomorphometrically. Results obtained on the lased condyles showed good cell morphology and a regular aspect of the repaired osteocartilaginous tissue.
authors.affiliation: Department of Experimental Surgery, Rizzoli Orthopedic Institute, Bologna, Italy.
authors.forename: G A
authors.initials: GA
authors.lastname: Guzzardella
authors.forename: D
authors.initials: D
authors.lastname: Tigani
authors.forename: P
authors.initials: P
authors.lastname: Torricelli
authors.forename: M
authors.initials: M
authors.lastname: Fini
authors.forename: L
authors.initials: L
authors.lastname: Martini
authors.forename: G
authors.initials: G
authors.lastname: Morrone
authors.forename: R
authors.initials: R
authors.lastname: Giardino
mesh_terms: D000818:Animals; D002356:Cartilage / Q000601:surgery*; D005269:Femur / Q000601:surgery*; D007719:Knee Joint / Q000601:surgery*; D053685:Laser Therapy; D008297:Male; D010812:Physical Stimulation; D011817:Rabbits; D014945:Wound Healing / Q000528:radiation effects*