A convergent strategy for the synthesis of beta-carba-galacto-disaccharides.
[reaction in text] A convergent strategy for the synthesis of beta-carba-galacto-disaccharides is illustrated by the preparation of 1 and 4, from a central "glycone" component 22, and the corresponding "aglycone" segments, monosaccharide alcohols, 23a or 23b. The key step is the formation of the carbasugar ring via an oxocarbenium ion-enol ether cyclization.
Cheng
X
X
Department of Chemistry, Hunter College/CUNY, 695 Park Avenue, New York, New York 10021, USA.
Khan
N
N
Kumaran
G
G
Mootoo
D R
DR
D003500:Cyclization; D004187:Disaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D005697:Galactosides / Q000138:chemical synthesis* / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods; D015394:Molecular Structure; D013329:Structure-Activity Relationship
D004187:Disaccharides; D005697:Galactosides