title: Automatic bolus tracking in monophasic spiral CT of the liver: liver-to-lesion conspicuity.
abstract: The aim of this study was to evaluate the value of automatic bolus tracking for monophasic spiral CT of the liver and to assess the liver-to-lesion conspicuity in comparison with time-delay examinations. In 40 patients scheduled for therapy control of known hypovascular hepatic metastases a monophasic spiral CT was completed either with time delay of 65 s (n = 20) or with automatic bolus tracking in the liver parenchyma (n = 20). Examinations were performed with 120 ml of contrast material and a flow rate of 3.0 ml/s. For automatic bolus tracking a parenchymal enhancement threshold of 40 HU was used. Contrast enhancement in the liver parenchyma and in liver lesions was obtained by means of regions of interest (ROI). Mean parenchymal enhancement was not significantly different between time delay and bolus-tracking group. In 4 of 20 patients in the bolus-tracking group the threshold level of 40 HU was not reached. With automatic bolus tracking a significantly higher liver-to-lesion density difference was observed (P < 0.0001). Automatic bolus tracking allows a better liver-to-lesion conspicuity in monophasic spiral CT. Contrary to recent studies, a significantly higher parenchymal enhancement was not found using automatic bolus tracking.
authors.affiliation: Department of Diagnostic Radiology, Eberhard Karls University, Hoppe-Seyler-Strasse 3, 72076 Tübingen, Germany. florian.mehnert@t-online.de
authors.forename: F
authors.initials: F
authors.lastname: Mehnert
authors.forename: P L
authors.initials: PL
authors.lastname: Pereira
authors.forename: J
authors.initials: J
authors.lastname: Trübenbach
authors.forename: A F
authors.initials: AF
authors.lastname: Kopp
authors.forename: C D
authors.initials: CD
authors.lastname: Claussen
mesh_terms: D000328:Adult; D000368:Aged; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007472:Iohexol / Q000008:administration & dosage* / Q000031:analogs & derivatives; D008113:Liver Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000556:secondary; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007472:Iohexol; C038192:iopromide