Bladder instillation of "naked" hSlo/pcDNA3 ameliorates detrusor hyperactivity in obstructed rats in vivo.
Christ
G J
GJ
Department of Urology, Institute for Smooth Muscle Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
Day
N S
NS
Santizo
C
C
Zhao
W
W
Sclafani
T
T
Karicheti
V
V
Valcic
M
M
Melman
A
A
D000818:Animals; D018076:DNA, Complementary / Q000627:therapeutic use; D005260:Female; D015316:Genetic Therapy / Q000379:methods*; D051036:Large-Conductance Calcium-Activated Potassium Channels; D009119:Muscle Contraction; D009130:Muscle, Smooth / Q000187:drug effects* / Q000503:physiopathology; D024681:Potassium Channels, Calcium-Activated / Q000235:genetics / Q000627:therapeutic use*; D051381:Rats; D017207:Rats, Sprague-Dawley; D001743:Urinary Bladder / Q000187:drug effects* / Q000503:physiopathology; D001748:Urinary Bladder Neck Obstruction / Q000503:physiopathology / Q000628:therapy*
D018076:DNA, Complementary; D051036:Large-Conductance Calcium-Activated Potassium Channels; D024681:Potassium Channels, Calcium-Activated