title: Pigmented pleomorphic xanthoastrocytoma: report of a rare case with review of the literature.
abstract: We describe a rare case of melanotic pleomorphic xanthoastrocytoma in a 32-year-old man who presented with partial complex seizures. Radiologically, the mass was located in the medial temporal lobe and was solid and cystic. Microscopic examination revealed features of a pleomorphic xanthoastrocytoma with some heavily pigmented cells. The pigment was demonstrated to be melanosomal melanin, which was confirmed by special stains, immunohistochemistry, and electron microscopy.
authors.affiliation: Departments of Pathology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: M C
authors.initials: MC
authors.lastname: Sharma
authors.forename: R
authors.initials: R
authors.lastname: Arora
authors.forename: N
authors.initials: N
authors.lastname: Khanna
authors.forename: V P
authors.initials: VP
authors.lastname: Singh
authors.forename: C
authors.initials: C
authors.lastname: Sarkar
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000378:metabolism / Q000473:pathology*; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D008297:Male; D008543:Melanins / Q000378:metabolism; D020460:Melanosomes / Q000473:pathology; D008854:Microscopy, Electron; D010858:Pigmentation; D013702:Temporal Lobe
chemical_list: D008543:Melanins