Ex vivo evidence that the phosphodiesterase inhibitor IBMX attenuates the up-regulation of PAR-2 in the endotoxemic rat aorta.
Kawabata
A
A
Kuroda
R
R
Nakaya
Y
Y
Kawao
N
N
Nishikawa
H
H
D015056:1-Methyl-3-isobutylxanthine / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D001011:Aorta / Q000378:metabolism / Q000473:pathology; D004730:Endothelium, Vascular / Q000378:metabolism / Q000473:pathology; D019446:Endotoxemia / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D010726:Phosphodiesterase Inhibitors / Q000008:administration & dosage / Q000494:pharmacology; D012333:RNA, Messenger / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D044464:Receptor, PAR-2; D018179:Receptors, Thrombin / Q000235:genetics / Q000502:physiology*; D015854:Up-Regulation / Q000187:drug effects
D010726:Phosphodiesterase Inhibitors; D012333:RNA, Messenger; D044464:Receptor, PAR-2; D018179:Receptors, Thrombin; D015056:1-Methyl-3-isobutylxanthine