title: Ultra high field MRI at 8 Tesla of subacute hemorrhagic stroke.
abstract: OBJECTIVE
  Optimal treatment strategies and neurologic outcome after stroke depend on an accurate characterization of the lesion. There is a need for high resolution noninvasive imaging for assessment of the infarct size, perfusion, and vascular territory. MRI at the ultra high field (UHF) of 8 T offers unprecedented resolution, but its utility for stroke evaluation has not been determined yet.
  
  
  METHODS
  A 55-year-old man with hypertension experienced sudden onset of speech arrest and right-sided hemiparesis that resolved in < 24 h with minimal neurologic deficit. MRI at 1.5 T showed initially a left posterior frontal lesion with subacute infarct (hyperintense on T2-weighted spin echo images) and right-sided frontal and periventricular lesions consistent with chronic infarct. There were many smaller white matter lesions. Delayed studies showed high signal changes involving the gray matter only on T1-weighted images.
  
  
  RESULTS
  Gradient echo and rapid acquisition with relaxation enhancement (RARE) multislice images revealed a serpentine area of low signal in the left posterior frontal lobe gray matter suggestive of a hemorrhagic infarct, right-sided frontal lesion also showing iron deposits, multiple periventricular and cortical areas with abnormal high signal regions that were consistent with old infarcts, and numerous small vessels readily visible, more prominent on the right.
  
  
  CONCLUSIONS
  MRI at 8 T displays lesions with a high resolution and striking anatomic details. Susceptibility to iron and sensitivity to detect blood products are increased at 8 T. The imaging characteristics at high field are different from those at low field, but both represent findings of iron products.
authors.affiliation: Department of Neurology, Ohio State University, Columbus 43210, USA. novak.91@osu.edu
authors.forename: V
authors.initials: V
authors.lastname: Novak
authors.forename: A
authors.initials: A
authors.lastname: Kangarlu
authors.forename: A
authors.initials: A
authors.lastname: Abduljalil
authors.forename: P
authors.initials: P
authors.lastname: Novak
authors.forename: A
authors.initials: A
authors.lastname: Slivka
authors.forename: D
authors.initials: D
authors.lastname: Chakeres
authors.forename: P M
authors.initials: PM
authors.lastname: Robitaille
mesh_terms: D006801:Humans; D006973:Hypertension / Q000150:complications; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000175:diagnosis* / Q000209:etiology