title: Phenylnaphthalene compounds from the subterranean part of Vitex rotundifolia and their antibacterial activity against methicillin-resistant Staphylococcus aureus.
abstract: A careful investigation of the subterranean part of Vitex rotundifolia has shown that this plant contains five novel lignans having a 1-phenylnaphthalene-type skeleton together with four known lignans. These structures were elucidated on the basis of spectroscopic data. Furthermore, some of the isolated compounds showed antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).
authors.affiliation: Faculty of Pharmaceutical Sciences, The University of Tokushima, Tokushima, 770-8505, Japan. kawazoe@ph2.tohushima-u.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Kawazoe
authors.forename: A
authors.initials: A
authors.lastname: Yutani
authors.forename: K
authors.initials: K
authors.lastname: Tamemoto
authors.forename: S
authors.initials: S
authors.lastname: Yuasa
authors.forename: H
authors.initials: H
authors.lastname: Shibata
authors.forename: T
authors.initials: T
authors.lastname: Higuti
authors.forename: Y
authors.initials: Y
authors.lastname: Takaishi
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001208:Asia; D013058:Mass Spectrometry; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D009281:Naphthalenes / Q000302:isolation & purification* / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D009281:Naphthalenes