title: Subcutaneous panniculitic T cell lymphoma mimicking histiocytic cytophagic panniculitis in a child.
abstract: Subcutaneous panniculitic T-cell lymphoma is a very rare malignancy in the pediatric age group, its association with hemophagocytic syndrome had been described but the association with the skin lesions mimicking histiocytic cytophagic panniculitis which is characteristic of hemophagocytic syndrome has not, to our knowledge, been described in children. We report a child with panniculitic T-cell lymphoma associated with bone marrow hemophagocytosis and subcutaneous histiocytic infiltration with active phagocytosis simulating histiocytic cytophagic. We stress the importance of searching for T-cell lymphoma in patients with panniculitis and hemophagocytic syndrome.
authors.affiliation: Department of Pediatric Cardiology, King Fahad National Guard Hospital, PO Box 22490, Riyadh 11426, Kingdom of Saudi Arabia.
authors.forename: S K
authors.initials: SK
authors.lastname: Ali
authors.forename: N M
authors.initials: NM
authors.lastname: Othman
authors.forename: A B
authors.initials: AB
authors.lastname: Tagoe
authors.forename: A A
authors.initials: AA
authors.lastname: Tulba
mesh_terms: D001707:Biopsy, Needle; D001853:Bone Marrow / Q000473:pathology*; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008297:Male; D015434:Panniculitis / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D018570:Risk Assessment; D012720:Severity of Illness Index; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy