title: Paramecium genome survey: a pilot project.
abstract: A consortium of laboratories undertook a pilot sequencing project to gain insight into the genome of Paramecium. Plasmid-end sequencing of DNA fragments from the somatic nucleus together with similarity searches identified 722 potential protein-coding genes. High gene density and uniform small intron size make random sequencing of somatic chromosomes a cost-effective strategy for gene discovery in this organism.
authors.affiliation: Service de Bioinformatique, UMS825 CNRS/SC13 INSERM, 7 rue Guy Môquet BP8, 94801 Villejuif Cedex, France.
authors.forename: P
authors.initials: P
authors.lastname: Dessen
authors.forename: M
authors.initials: M
authors.lastname: Zagulski
authors.forename: R
authors.initials: R
authors.lastname: Gromadka
authors.forename: H
authors.initials: H
authors.lastname: Plattner
authors.forename: R
authors.initials: R
authors.lastname: Kissmehl
authors.forename: E
authors.initials: E
authors.lastname: Meyer
authors.forename: M
authors.initials: M
authors.lastname: Bétermier
authors.forename: J E
authors.initials: JE
authors.lastname: Schultz
authors.forename: J U
authors.initials: JU
authors.lastname: Linder
authors.forename: R E
authors.initials: RE
authors.lastname: Pearlman
authors.forename: C
authors.initials: C
authors.lastname: Kung
authors.forename: J
authors.initials: J
authors.lastname: Forney
authors.forename: B H
authors.initials: BH
authors.lastname: Satir
authors.forename: J L
authors.initials: JL
authors.lastname: Van Houten
authors.forename: A M
authors.initials: AM
authors.lastname: Keller
authors.forename: M
authors.initials: M
authors.lastname: Froissard
authors.forename: L
authors.initials: L
authors.lastname: Sperling
authors.forename: J
authors.initials: J
authors.lastname: Cohen
mesh_terms: D000818:Animals; D018503:Genome, Protozoan; D006801:Humans; D010247:Paramecium / Q000145:classification / Q000235:genetics*; D010802:Phylogeny; D010865:Pilot Projects; D015800:Protozoan Proteins / Q000235:genetics
chemical_list: D015800:Protozoan Proteins