title: Reversal of primary root caries using a dentifrice with a high fluoride content.
abstract: Root caries is a widespread problem and can be quite serious in older populations. The restoration of root carious lesions is often difficult. Compared to enamel caries, there has been limited research into the pharmaceutical management of primary root caries lesions (PRCLs), and many of these studies have been carried out in vitro, with limited numbers of clinical trials. Fluoride is presently a cornerstone in dentifrice formulations for cost-effective and anticaries therapy. It is generally accepted that fluoride ions promote remineralization of tooth substances and reduce the rate of demineralization. The use of a dentifrice with a high fluoride content may be considered to reverse PRCLs, since more fluoride is required for the remineralization of roots than for enamel. This paper reviews the effects of dentifrices with high fluoride contents on the management of root caries.
authors.affiliation: Restorative Dentistry and Gerodontology, Queen's University Belfast, Northern Ireland. e.lynch@qub.ac.uk
authors.forename: E
authors.initials: E
authors.lastname: Lynch
authors.forename: A
authors.initials: A
authors.lastname: Baysan
mesh_terms: D000328:Adult; D000367:Age Factors; D002327:Cariostatic Agents / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*; D003362:Cost-Benefit Analysis; D003731:Dental Caries / Q000191:economics / Q000517:prevention & control; D003743:Dental Enamel / Q000378:metabolism; D003802:Dentifrices / Q000032:analysis / Q000191:economics / Q000627:therapeutic use*; D005459:Fluorides / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*; D006801:Humans; D017213:Root Caries / Q000517:prevention & control*; D014089:Tooth Remineralization; D014092:Tooth Root / Q000378:metabolism
chemical_list: D002327:Cariostatic Agents; D003802:Dentifrices; D005459:Fluorides