Primary spontaneous pneumothorax in two siblings suggests autosomal recessive inheritance.
We report on a sister and brother with recurrent spontaneous pneumothorax without underlying connective tissue disease and without other affected relatives. The occurrence of spontaneous pneumothorax in two siblings from a large Finnish family raises the possibility of autosomal recessive inheritance of this disorder in some patients.
Koivisto
P A
PA
Department of Clinical Genetics, Tampere University Hospital, Tampere, Finland. blpako@uta.fi
Mustonen
A
A
D000328:Adult; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D008297:Male; D010375:Pedigree; D011030:Pneumothorax / Q000235:genetics*; D012008:Recurrence