title: Studies on psychopharmacological activity of Andrographis paniculata extract.
abstract: Psychopharmacological studies were conducted on an extract of Andrographis paniculata herbs. The extract exhibited a significant alteration in behaviour pattern and a reduction in spontaneous motility. The extract also produced a prolongation of the pentobarbitone-induced sleeping time and lowered the body temperature in different experimental animal models.
authors.affiliation: Division of Pharmacognosy, Department of Pharmaceutical Technology, Jadavpur University, Calcutta 700 032, India.
authors.forename: S C
authors.initials: SC
authors.lastname: Mandal
authors.forename: A K
authors.initials: AK
authors.lastname: Dhara
authors.forename: B C
authors.initials: BC
authors.lastname: Maiti
mesh_terms: D019342:Acetic Acid; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D019684:Magnoliopsida; D051379:Mice; D010146:Pain / Q000139:chemically induced / Q000517:prevention & control*; D010147:Pain Measurement / Q000187:drug effects; D010433:Pentylenetetrazole; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D010946:Plants, Medicinal; D011619:Psychotropic Drugs / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D012640:Seizures / Q000139:chemically induced / Q000517:prevention & control*; D013331:Strychnine
chemical_list: D010936:Plant Extracts; D011619:Psychotropic Drugs; D013331:Strychnine; D019342:Acetic Acid; D010433:Pentylenetetrazole