title: Echo-enhanced transcranial color-coded US: clinical usefulness of intravenous infusion versus bolus injection of SH U 508A.
abstract: Twelve patients with insufficient transcranial Doppler signal underwent transcranial color-coded ultrasonography before and after administration of SH U 508A with different modes of administration. Clinically useful enhancement time after bolus injection was surpassed by that after standard infusion (1 mL/min), whereas further prolongation was observed after individualized infusion. Intravenous infusion of SH U 508A provides a prolonged useful enhancement compared with that after bolus injection.
authors.affiliation: Department of Neurology, University of Regensburg, Universitätsstrasse 84, D-93053 Regensburg, Germany. thilo@hoelscher@klinik.uni-regensburg.de
authors.forename: T
authors.initials: T
authors.lastname: Hölscher
authors.forename: F
authors.initials: F
authors.lastname: Schlachetzki
authors.forename: A
authors.initials: A
authors.lastname: Bauer
authors.forename: L
authors.initials: L
authors.lastname: Rosin
authors.forename: B
authors.initials: B
authors.lastname: Götz
authors.forename: U
authors.initials: U
authors.lastname: Bogdahn
mesh_terms: D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D011134:Polysaccharides / Q000008:administration & dosage*; D013997:Time Factors; D017585:Ultrasonography, Doppler, Transcranial; D014652:Vascular Diseases / Q000000981:diagnostic imaging
chemical_list: D003287:Contrast Media; D011134:Polysaccharides; C059891:SHU 508