title: Partial frontolateral laryngectomy with epiglottic reconstruction for management of early-stage glottic carcinoma.
abstract: OBJECTIVE
  The aim of this study was to demonstrate that partial frontolateral laryngectomy with epiglottic reconstruction (PFLER) is an effective therapeutic option for treatment of T1 and T2 glottic carcinoma.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Between 1982 and 1997, we treated 127 cases of early glottic carcinoma with PFLER. Early glottic carcinoma was staged using the Union Internationale Contre le Cancer TNM classification as either T1N0M0 (62 cases) or T2N0M0 (65 cases). Selection criteria, depending on the limits of exeresis, must remain glottic carcinoma with less than 0.5 cm of anterior subglottic involvement, with no involvement of the supraglottic space or laryngeal side of the epiglottis, with involvement of only one arytenoid, and with good mobility of both arytenoids even if vocal cord mobility is decreased.
  
  
  RESULTS
  Postoperative recovery was uneventful in all cases, and all patients but one were able to breath and eat normally. The failure involved a patient with a permanent gastrostomy. As with other partial laryngectomy techniques, the main drawback of PFLER was deterioration of voice quality. All patients presented hoarseness and weakness of the voice. Five-year survival rates calculated according to the Kaplan-Meier method were 91% (standard error, 5%) in the T1N0M0 group and 86% (standard error, 5%) in the T2N0M0 group. No recurrence was observed in the T1N0M0 group. Local control was successful in 92% in the T2N0M0 group after a median follow-up of 5 years.
  
  
  CONCLUSIONS
  These findings show that PFLER is an effective therapeutic option in selected cases of early T1N0M0 or T2N0M0 glottic carcinoma.
authors.affiliation: Fédération ORL Centre Hospitalo-Universitaire Timone, Marseille, France.
authors.forename: A
authors.initials: A
authors.lastname: Giovanni
authors.forename: B
authors.initials: B
authors.lastname: Guelfucci
authors.forename: R
authors.initials: R
authors.lastname: Gras
authors.forename: P
authors.initials: P
authors.lastname: Yu
authors.forename: M
authors.initials: M
authors.lastname: Zanaret
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D004825:Epiglottis / Q000601:surgery*; D005260:Female; D005931:Glottis; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures / Q000379:methods*; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome