NO or H(2)O(2) for endothelium-dependent vasorelaxation: Tetrahydrobiopterin makes the difference.
van Hinsbergh
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D000818:Animals; D001161:Arteriosclerosis / Q000188:drug therapy; D001708:Biopterins / Q000031:analogs & derivatives* / Q000502:physiology* / Q000627:therapeutic use; D004730:Endothelium, Vascular / Q000378:metabolism*; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism*; D051379:Mice; D009569:Nitric Oxide / Q000096:biosynthesis*; D019001:Nitric Oxide Synthase / Q000378:metabolism; D052247:Nitric Oxide Synthase Type II; D052250:Nitric Oxide Synthase Type III; D014664:Vasodilation
D001708:Biopterins; D009569:Nitric Oxide; D006861:Hydrogen Peroxide; C496314:NOS3 protein, human; D019001:Nitric Oxide Synthase; D052247:Nitric Oxide Synthase Type II; D052250:Nitric Oxide Synthase Type III; C496315:Nos3 protein, mouse; C003402:sapropterin