Effects of synthetic cecropin analogs on in vitro growth of Acholeplasma laidlawii.
Four synthetic peptides (Peptidyl MIMs; Demeter Biotechnologies, Inc.) were evaluated for their in vitro activity against Acholeplasma laidlawii. Fifty percent effective concentration values ranged from 1 to 15 microM. Three of these compounds are more lethal than cecropin B against A. laidlawii.
Borth
W B
WB
University of Hawaii, Department of Plant and Environmental Protection Sciences, Honolulu, Hawaii 96822, USA. borth@hawaii.edu
Jones
V P
VP
Ullman
D E
DE
Hu
J S
JS
D000128:Acholeplasma laidlawii / Q000187:drug effects* / Q000254:growth & development*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D019476:Insect Proteins / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D019476:Insect Proteins; C031162:cecropin B protein, Insecta