[Clinical study of CPD4-PDT for the prevention of postoperative recurrence in infiltrative bladder cancer].
OBJECTIVE
To assess the efficacy of chlorophyll derivative (CPD4)-Photodynamic therapy (PDT) in preventing postoperative recurrence of the infiltrative cancer of the urinary bladder.


METHODS
Thirty-two patients were treated with CPD4-PDT postoperationally to prevent the recurrence of cancer, all of which being followed up.


RESULTS
The recurrence rate was 42.1% in T2 tumors and 69.2% in T3 tumors (P < 0.05), and the survival period without tumor has been 19.8 +/- 14.8 months in T2 tumors, and 22.67 +/- 19.72 months in T3 tumors (P > 0.05). There was very significant difference in recurrent rate between grade I and grade II, III patients (0 and 66.7%, P < 0.001).


CONCLUSIONS
CPD4-PDT is a safe and effective measure to prevent the recurrence in infiltrative bladder cancer after operation.
Liu
S
S
Affiliated Hospital, Zhejiang TCM College, Hangzhou(310006).
Yang
Y
Y
Wang
Z
Z
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000601:surgery*; D002734:Chlorophyll / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use; D011184:Postoperative Period; D011446:Prospective Studies; D001749:Urinary Bladder Neoplasms / Q000601:surgery*
D017319:Photosensitizing Agents; D002734:Chlorophyll