title: The role of radical nephrectomy in metastatic renal cell carcinoma.
abstract: The role of cytoreductive surgery in patients with metastatic renal cancer remains controversial. Recent data from our Southwest Oncology Group trial suggest that cytoreduction confers an approximately 50% increase in median survival for such patients when they are treated with interferon-alfa-2b immunotherapy. The timing of cytoreduction, and in which patients it may be most applicable, are discussed herein.
authors.affiliation: Department of Urology, Loyola University Medical Center, Maywood, IL 60153-5500, USA.
authors.forename: R C
authors.initials: RC
authors.lastname: Flanigan
authors.forename: P M
authors.initials: PM
authors.lastname: Yonover
mesh_terms: D002292:Carcinoma, Renal Cell / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D007680:Kidney Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D009362:Neoplasm Metastasis; D009392:Nephrectomy; D011379:Prognosis; D015996:Survival Rate