A reliable, nondestructive animal model for interstitial cystitis: intravesical low-dose protamine sulfate combined with physiological concentrations of potassium chloride.
Fraser
M O
MO
Department of Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Chuang
Y C
YC
Lavelle
J P
JP
Yoshimura
N
N
de Groat
W C
WC
Chancellor
M B
MB
D000818:Animals; D018856:Cystitis, Interstitial / Q000139:chemically induced*; D004195:Disease Models, Animal; D005260:Female; D006494:Heparin Antagonists / Q000008:administration & dosage; D011189:Potassium Chloride / Q000008:administration & dosage; D011479:Protamines / Q000008:administration & dosage; D051381:Rats; D017207:Rats, Sprague-Dawley
D006494:Heparin Antagonists; D011479:Protamines; D011189:Potassium Chloride