title: Approaches towards understanding methionine biosynthesis in higher plants.
abstract: Plants are able to synthesise all amino acids essential for human and animal nutrition. Because the concentrations of some of these dietary constituents, especially methionine, lysine, and threonine, are often low in edible plant sources, research is being performed to understand the physiological, biochemical, and molecular mechanisms that contribute to their transport, synthesis and accumulation in plants. This knowledge can be used to develop strategies allowing a manipulation of crop plants, eventually improving their nutritional quality. This article is intended to serve two purposes. The first is to provide a brief review on the physiology of methionine synthesis in higher plants. The second is to highlight some recent findings linked to the metabolism of methionine in plants due to its regulatory influence on the aspartate pathway and its implication in plant growth. This information can be used to develop strategies to improve methionine content of plants and to provide crops with a higher nutritional value.
authors.affiliation: Angewandte Genetik, Institut für Biologie, Freie Universität Berlin, Federal Republic of Germany. hesse@mpimp-golm.mpg.de
authors.forename: H
authors.initials: H
authors.lastname: Hesse
authors.forename: O
authors.initials: O
authors.lastname: Kreft
authors.forename: S
authors.initials: S
authors.lastname: Maimann
authors.forename: M
authors.initials: M
authors.lastname: Zeh
authors.forename: L
authors.initials: L
authors.lastname: Willmitzer
authors.forename: R
authors.initials: R
authors.lastname: Höfgen
mesh_terms: D013766:5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase / Q000378:metabolism; D019757:Carbon-Oxygen Lyases / Q000378:metabolism; D003541:Cystathionine beta-Synthase / Q000378:metabolism; D006710:Homocysteine / Q000378:metabolism; D008715:Methionine / Q000096:biosynthesis*; D008967:Molecular Biology / Q000379:methods* / Q000639:trends; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D030821:Plants, Genetically Modified / Q000235:genetics / Q000378:metabolism
chemical_list: D006710:Homocysteine; D008715:Methionine; D013766:5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; C022696:O-succinylhomoserine (thiol)-lyase; D019757:Carbon-Oxygen Lyases; D003541:Cystathionine beta-Synthase