[Significance of detecting E-selectin of serum and pleural effusion in differentiating benign and malignant diseases].
OBJECTIVE
To evaluate the significance of detecting E-selectin of serum and pleural effusion in differentiating benign and malignant diseases.


METHODS
E-selectin of serum and pleural effusion in 23 patients with tuberculous pleurisy and 21 patients with lung cancer involving pleura was detected by ELISA method.


RESULTS
E-selectin of serum(44 +/- 5 micrograms/L) and pleural effusion (24 +/- 3 micrograms/L) in patients with tuberculous pleurisy was much higher than that of serum (27 +/- 4 micrograms/L) and pleural effusion (11 +/- 3 micrograms/L) in lung cancer patients (P < 0.01). In addition, E-selection of serum in patients with tuberculous pleurisy was also much higher than that of pleural effusion (P < 0.01). And there was no correlation between E-selectin of serum and that of pleural effusion in patients with tuberculous pleurisy (r = 0.16, P > 0.05).


CONCLUSIONS
E-selectin of serum and pleural effusion in patients with tuberculous pleurisy is produced from different sources. And E-selectin in patients with tuberculous pleurisy is much higher than those with lung cancer. Thence detecting E-selectin of serum and pleural effusion might be helpful for differentiating benign and malignant diseases.
Liu
G
G
Department of Respiratory Diseases, First Affiliated Hospital of Guangxi Medical University, Nanning 530021.
Li
C
C
Zhong
X
X
D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D019040:E-Selectin / Q000032:analysis / Q000097:blood*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications; D008297:Male; D008875:Middle Aged; D010996:Pleural Effusion / Q000378:metabolism; D016066:Pleural Effusion, Malignant / Q000175:diagnosis* / Q000209:etiology; D014396:Tuberculosis, Pleural / Q000175:diagnosis*
D019040:E-Selectin