title: Hortein, a new natural product from the fungus Hortaea werneckii associated with the sponge Aplysina aerophoba.
abstract: The fungus Hortaea werneckii isolated from the Mediterranean sponge Aplysina aerophoba, collected at Banyuls-sur-Mer in southern France, yielded a new compound named hortein (1), which possesses a unique ring system hitherto unknown for natural products. The structure of 1 was established on the basis of 1D and 2D NMR spectroscopic and mass spectrometric (ESI, CI, FAB, EI) data.
authors.affiliation: Heinrich-Heine-Universität, Institut für Pharmazeutische Biologie, Universitätsstrasse 1, Geb. 26.23, D-40255 Düsseldorf, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Brauers
authors.forename: R
authors.initials: R
authors.lastname: Ebel
authors.forename: R
authors.initials: R
authors.lastname: Edrada
authors.forename: V
authors.initials: V
authors.lastname: Wray
authors.forename: A
authors.initials: A
authors.lastname: Berg
authors.forename: U
authors.initials: U
authors.lastname: Gräfe
authors.forename: P
authors.initials: P
authors.lastname: Proksch
mesh_terms: D000818:Animals; D001419:Bacteria / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D007306:Insecticides / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008522:Mediterranean Sea; D008826:Microbial Sensitivity Tests; D011084:Polycyclic Aromatic Hydrocarbons / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D011161:Porifera / Q000382:microbiology*; D021241:Spectrometry, Mass, Electrospray Ionization; D016339:Spectrometry, Mass, Fast Atom Bombardment
chemical_list: D007306:Insecticides; D011084:Polycyclic Aromatic Hydrocarbons; C433955:hortein