title: A new high intensity focused ultrasound applicator for surgical applications.
abstract: Improved high-intensity focused ultrasound (HIFU) surgical applicators are required for use in a surgical environment. We report on the performance and characteristics of a new solid-cone HIFU applicator. Previous HIFU devices used a water-filled stand-off to couple the ultrasonic energy from the transducer to the treatment area. The new applicator uses a spherically-focused element and a solid aluminum cone to guide and couple the ultrasound to the tissue. Compared with the water-filled applicators, this new applicator is simpler to set up and manipulate, cannot leak, prevents the possibility of cavitation within the coupling device, and is much easier to sterilize and maintain during surgery. The design minimizes losses caused by shear wave conversion found in tapered solid acoustic velocity transformers operated at high frequencies. Computer simulations predicted good transfer of longitudinal waves. Impedance measurements, beam plots, Schlieren images, and force balance measurements verified strong focusing and suitable transfer of acoustic energy into water. At the focus, the -3 dB beam dimensions are 1.2 mm (axial) x 0.3 mm (transverse). Radiation force balance measurements indicate a power transfer efficiency of 40%. In vitro and in vivo tissue experiments confirmed the applicator's ability to produce hemostasis.
authors.affiliation: Department of Mechanical Engineering, University of Washington, Seattle, WA, USA. mbrentna@u.washington.edu
authors.forename: M D
authors.initials: MD
authors.lastname: Brentnall
authors.forename: R W
authors.initials: RW
authors.lastname: Martin
authors.forename: S
authors.initials: S
authors.lastname: Vaezy
authors.forename: P
authors.initials: P
authors.lastname: Kaczkowski
authors.forename: F
authors.initials: F
authors.lastname: Forster
authors.forename: L
authors.initials: L
authors.lastname: Crum
mesh_terms: D000162:Acoustics; D000818:Animals; D001808:Blood Vessels / Q000293:injuries; D003198:Computer Simulation; D017097:Electric Impedance; D006488:Hemostasis, Surgical / Q000295:instrumentation* / Q000379:methods; D008099:Liver / Q000293:injuries / Q000601:surgery; D008954:Models, Biological; D011817:Rabbits; D013154:Spleen / Q000293:injuries / Q000601:surgery; D014159:Transducers; D014464:Ultrasonic Therapy / Q000295:instrumentation* / Q000379:methods; D014656:Vascular Surgical Procedures / Q000295:instrumentation / Q000379:methods