title: Metabotropic glutamate receptors: structure and new subtype-selective ligands.
abstract: Metabotropic glutamate receptors (mGluRs) constitute an attractive target for the development of potential neuroprotective agents. Recent advances in the elucidation of the peculiar molecular architecture of mGluRs and in the design and synthesis of subtype selective ligands are discussed.
authors.affiliation: Dipartimento di Chimica e Tecnologia del Farmaco, Perugia, Italy. rp@unipg.it
authors.forename: R
authors.initials: R
authors.lastname: Pellicciari
authors.forename: G
authors.initials: G
authors.lastname: Costantino
authors.forename: M
authors.initials: M
authors.lastname: Marinozzi
authors.forename: A
authors.initials: A
authors.lastname: Macchiarulo
authors.forename: E
authors.initials: E
authors.lastname: Camaioni
authors.forename: B
authors.initials: B
authors.lastname: Natalini
mesh_terms: D000818:Animals; D006801:Humans; D018696:Neuroprotective Agents / Q000494:pharmacology*; D018094:Receptors, Metabotropic Glutamate / Q000037:antagonists & inhibitors* / Q000737:chemistry
chemical_list: D018696:Neuroprotective Agents; D018094:Receptors, Metabotropic Glutamate