Pigmented pleomorphic xanthoastrocytoma: report of a rare case with review of the literature.
We describe a rare case of melanotic pleomorphic xanthoastrocytoma in a 32-year-old man who presented with partial complex seizures. Radiologically, the mass was located in the medial temporal lobe and was solid and cystic. Microscopic examination revealed features of a pleomorphic xanthoastrocytoma with some heavily pigmented cells. The pigment was demonstrated to be melanosomal melanin, which was confirmed by special stains, immunohistochemistry, and electron microscopy.
Sharma
M C
MC
Departments of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Arora
R
R
Khanna
N
N
Singh
V P
VP
Sarkar
C
C
D000328:Adult; D001254:Astrocytoma / Q000378:metabolism / Q000473:pathology*; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D008297:Male; D008543:Melanins / Q000378:metabolism; D020460:Melanosomes / Q000473:pathology; D008854:Microscopy, Electron; D010858:Pigmentation; D013702:Temporal Lobe
D008543:Melanins