title: [A case of juvenile pilocytic astrocytoma with unusual neuroimaging features].
abstract: We present a case of cerebellar juvenile pilocytic astrocytoma(JPA) with unusual neuroimaging features. The patient was a 14-year-old male who suffered from chronic headaches for a couple of weeks. Plain craniogram showed a decalcification and bulging of the occipital bone. Computed tomography(CT) scans demonstrated low density multiple components with small calcifications in the right cerebellar hemisphere extending to the left. These calcifications were found at the margin of these multi-lobular components. Magnetic resonance imaging(MRI) revealed iso or low intensity on T1 weighted image, and slightly high intensity on T2 weighted image. The lesion indicated more heterogeneous and higher intensity than brain parenchyma on FLAIR imaging, and remarkable higher intensity than brain parenchyma with some small low intensity areas on diffusion weighted imaging. He underwent the complete resection except for the cranial tissue surrounding the pons. Histologic diagnosis was juvenile pilocytic astrocytoma, because of biphasic pattern of bipolar cells and a number of Rosenthal fibers. Generally JPA has sharp and smooth demarcated cysts with well-enhanced mural nodule. It was difficult to diagnose the presented tumor as JPA before operation, since its unusual neuroimaging resembled both dermoid and high grade gliomas.
authors.affiliation: Department of Neurosurgery, Hiroshima University Faculty of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Matsushige
authors.forename: H
authors.initials: H
authors.lastname: Yoshioka
authors.forename: F
authors.initials: F
authors.lastname: Yamasaki
authors.forename: K
authors.initials: K
authors.lastname: Sugiyama
authors.forename: K
authors.initials: K
authors.lastname: Arita
authors.forename: K
authors.initials: K
authors.lastname: Kurisu
authors.forename: O
authors.initials: O
authors.lastname: Hamasaki
authors.forename: T
authors.initials: T
authors.lastname: Yano
mesh_terms: D000293:Adolescent; D001254:Astrocytoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed