[Hormone therapy and cardiovascular risk].
Oral contraception, hormonal replacement therapy and hormonal therapy in cancer patients are commonly used in everyday practice. Venous and arterial thromboembolisms which are potentially fatal are among the most serious side effects experienced by women. In this review, we focus on the circulation, describing the hormonal alterations on hemostasis. The risk of thromboembolic event is discussed in relation with the different hormonal regimen. We will finally propose recommendations for oral contraception in presence of venous or cardiovascular risk factors.
Wütschert
R
R
Division d'angiologie et d'hémostase, Département de médecine interne, Hôpital Cantonal Universitaire de Genève.
Cirafici
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P
D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects*; D002318:Cardiovascular Diseases / Q000139:chemically induced*; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects*; D015914:Estrogen Replacement Therapy / Q000009:adverse effects*; D005260:Female; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D008297:Male; D012307:Risk Factors; D013923:Thromboembolism / Q000139:chemically induced
D018931:Antineoplastic Agents, Hormonal; D003278:Contraceptives, Oral, Hormonal