[The relationship between fetal fibronectin, bacteria vaginosis and chorioammionitis].
OBJECTIVE
To study the relationship of fetal fibronectin (FFN), Bacteria vaginosis (BV) and chorioamnionitis. To evaluate the diagnostic value of FFN for chorioamnionitis.


METHODS
FFN was measured by enzyme-labelled immunosordent assay (ELISA) in samples of carvical secretion from 60 pregnant women with BV (study group) and 45 normal pregnant women at same gestational weeks (control group). Positive test was defined as a level of (FFN) > or = 50 ng/ml.


RESULTS
Positive rate of FFN in pregnant women with BV was significantly higher than that in the normal control group. Incidence of chorioamnionitis and preterm labor in FFN positive cases was significantly higher than that of FFN negative cases.


CONCLUSIONS
Fetal fibronectin is an important marker for diagnosis and prediction of chorioamnionitis perterm labor and Premature rupture of membranes.
Wang
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Second Hospital of Norman Berthune Medical University, Chang Chun 130041.
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D002821:Chorioamnionitis / Q000209:etiology*; D005260:Female; D005333:Fetus / Q000378:metabolism*; D005353:Fibronectins / Q000378:metabolism*; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000378:metabolism*; D011256:Pregnancy Outcome; D016585:Vaginosis, Bacterial / Q000378:metabolism*
D005353:Fibronectins