title: A mild anionic method for generating o-quinone methides: facile preparations of ortho-functionalized phenols.
abstract: A low-temperature method for generating o-quinone methides is described which permits facile introduction of assorted R substituents onto the aryl ring system at low temperature. The method is useful for the efficient preparation of ortho-ring-alkylated phenols.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106-9510, USA.
authors.forename: R M
authors.initials: RM
authors.lastname: Jones
authors.forename: R W
authors.initials: RW
authors.lastname: Van De Water
authors.forename: C C
authors.initials: CC
authors.lastname: Lindsey
authors.forename: C
authors.initials: C
authors.lastname: Hoarau
authors.forename: T
authors.initials: T
authors.lastname: Ung
authors.forename: T R
authors.initials: TR
authors.lastname: Pettus
mesh_terms: D000477:Alkylating Agents; D001685:Biological Factors / Q000138:chemical synthesis; D020650:Combinatorial Chemistry Techniques; D010636:Phenols / Q000138:chemical synthesis; D011809:Quinones / Q000138:chemical synthesis*
chemical_list: D000477:Alkylating Agents; D001685:Biological Factors; D010636:Phenols; D011809:Quinones