title: Structure revision and assignment of absolute stereochemistry of a marine C21 bisfuranoterpene.
abstract: The C21 bisfuranoterpene (-)-isotetradehydrofurospongin-1 (6), previously isolated from a Western Australian Spongia sp., has been reisolated from a specimen of Spirastrella papilosa collected during scientific trawling operations in the Great Australian Bight. A 2D NMR analysis of 6 has prompted reassignment of the published structure 5, while degradation and chiral HPLC analysis have allowed determination of the absolute stereochemistry.
authors.affiliation: School of Chemistry, University of Melbourne, Parkville, Victoria, 3010, Australia. r.capon@unimelb.edu.au
authors.forename: R J
authors.initials: RJ
authors.lastname: Capon
authors.forename: A
authors.initials: A
authors.lastname: Jenkins
authors.forename: F
authors.initials: F
authors.lastname: Rooney
authors.forename: E L
authors.initials: EL
authors.lastname: Ghisalberti
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D005663:Furans / Q000737:chemistry* / Q000302:isolation & purification; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010126:Ozone; D011161:Porifera / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D005663:Furans; C433914:isotetradehydrofurospongin-1; D010126:Ozone