Synthetic studies toward diazonamide A. A novel approach for polyoxazole synthesis.
[Reaction in text]The indole-bisoxazole fragment of diazonamide A was prepared by a Chan-type rearrangement of a tertiary amide. This approach represents a remarkably direct strategy for polyoxazole synthesis.
Wipf
P
P
Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA. pwipf+@pitt.edu
Methot
J L
JL
D000577:Amides / Q000737:chemistry; D000818:Animals; D001688:Biological Products / Q000737:chemistry*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry*; D015394:Molecular Structure; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D013329:Structure-Activity Relationship; D014561:Urochordata
D000577:Amides; D001688:Biological Products; D006576:Heterocyclic Compounds, 4 or More Rings; D010080:Oxazoles; D011108:Polymers; C408862:diazonamide A