title: The successful treatment of lupus pernio with the flashlamp pulsed dye laser.
abstract: Lupus pernio of the nose is the most characteristic cutaneous lesion of sarcoidosis. It is cosmetically disfiguring and can be the cause of significant morbidity. In particular, the affected skin is often red or purple due to increased vasculature. It is particularly resistant to both surgical and medical therapy. We describe a patient with lupus pernio affecting her nose, which showed a dramatic improvement following treatment with the pulse dye laser (PDL). A biopsy taken after treatment showed the continued presence of sarcoidal granulomas. We therefore feel that treatment with the PDL is an effective tool in improving the cosmetic appearance of lupus pernio, but does not influence the underlying disease process.
authors.affiliation: Department of Dermatology, St Helier Hospital, Wrythe Lane, Carshalton, Surrey SM5 1AA, UK.
authors.forename: S
authors.initials: S
authors.lastname: Cliff
authors.forename: R H
authors.initials: RH
authors.lastname: Felix
authors.forename: L
authors.initials: L
authors.lastname: Singh
authors.forename: C C
authors.initials: CC
authors.lastname: Harland
mesh_terms: D005260:Female; D006801:Humans; D053685:Laser Therapy; D008875:Middle Aged; D009668:Nose Diseases / Q000473:pathology / Q000532:radiotherapy*; D012507:Sarcoidosis / Q000473:pathology / Q000532:radiotherapy*; D012871:Skin Diseases / Q000473:pathology / Q000532:radiotherapy*