title: Repression of MHC determinants in HIV infection.
abstract: HIV infects CD4(+) macrophages and lymphocytes. Before the development of AIDS, HIV weakens the immune system in part by blocking antigen processing and presentation via major histocompatibility complex (MHC) molecules. In this report, we discuss how HIV escapes the immune surveillance by MHC II molecules.
authors.affiliation: Department of Medicine, Howard Hughes Medical Institute, University of California, San Francisco, California 94143-0703, USA.
authors.forename: S
authors.initials: S
authors.lastname: Kanazawa
authors.forename: B
authors.initials: B
authors.lastname: Matija Peterlin
mesh_terms: D000914:Antibodies, Viral / Q000276:immunology*; D005802:Genes, MHC Class II; D006678:HIV / Q000235:genetics / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000235:genetics / Q000276:immunology*; D006801:Humans
chemical_list: D000914:Antibodies, Viral; D000949:Histocompatibility Antigens Class II