title: [Synthesis and properties of O- and S-glycosylated derivatives of pyropheophorbide a].
abstract: New O- and S-glycosylated derivatives of pyropheophorbide a were synthesized in the context of the design of photosensitizers for photodynamic cancer therapy. The resulting amphiphilic conjugates were found to be sufficiently water-soluble and suitable for the study of the photosensitizer penetration and accumulation in tumors.
authors.affiliation: Lomonosov State Academy of Fine Chemical Technology, pr. Vernadskogo 86, Moscow, 117571 Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Aksenova
authors.forename: Iu L
authors.initials: IuL
authors.lastname: Sebiakin
authors.forename: A F
authors.initials: AF
authors.lastname: Mironov
mesh_terms: D002734:Chlorophyll / Q000031:analogs & derivatives* / Q000737:chemistry*; D006031:Glycosylation; D009682:Magnetic Resonance Spectroscopy; D017319:Photosensitizing Agents / Q000138:chemical synthesis* / Q000737:chemistry; D013053:Spectrophotometry
chemical_list: D017319:Photosensitizing Agents; D002734:Chlorophyll; C040298:pyropheophorbide a