title: Standardization of laboratory data and establishment of reference intervals in the Fukuoka Prefecture: a Japanese perspective.
abstract: Standardization of 22 clinical chemistry analytes and five serum protein constituents has been performed in the Fukuoka Prefecture, which has a population of approximately five million. The standardization project was established to determine reference intervals for these analytes by educating physicians, medical technologists and staff of medical institutions, and by daily or monthly monitoring the use of common control samples through e-mail. Standardization extended to 97% of the institutions in the prefecture. Results for 14 of the 22 clinical chemistry analytes have become highly reliable and differences between institutions decreased. Standardization of other analytes is now in progress. Regional collaboration based on international guidelines led to a significant improvement in interlaboratory comparability. Areas where further improvements are needed have been identified.
authors.affiliation: The Association of Five Hospitals in Fukuoka Prefecture, Fukuoka, Japan. kinosita@cclm.med.kyushu-ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Kinoshita
authors.forename: M
authors.initials: M
authors.lastname: Toyofuku
authors.forename: H
authors.initials: H
authors.lastname: Iida
authors.forename: M
authors.initials: M
authors.lastname: Wakiyama
authors.forename: M
authors.initials: M
authors.lastname: Kurihara
authors.forename: M
authors.initials: M
authors.lastname: Nakahara
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authors.initials: M
authors.lastname: Nakata
authors.forename: K
authors.initials: K
authors.lastname: Nakashima
authors.forename: S
authors.initials: S
authors.lastname: Seo
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authors.initials: N
authors.lastname: Hosaka
authors.forename: J
authors.initials: J
authors.lastname: Yano
authors.forename: T
authors.initials: T
authors.lastname: Misumoto
authors.forename: H
authors.initials: H
authors.lastname: Ishihara
authors.forename: K
authors.initials: K
authors.lastname: Ikeda
authors.forename: M
authors.initials: M
authors.lastname: Tsuchihashi
authors.forename: H
authors.initials: H
authors.lastname: Kawashima
authors.forename: Y
authors.initials: Y
authors.lastname: Imoto
authors.forename: K
authors.initials: K
authors.lastname: Imamura
authors.forename: Y
authors.initials: Y
authors.lastname: Urabe
authors.forename: K
authors.initials: K
authors.lastname: Shinohara
authors.forename: K
authors.initials: K
authors.lastname: Ooishi
authors.forename: T
authors.initials: T
authors.lastname: Abe
authors.forename: J
authors.initials: J
authors.lastname: Jinnouchi
authors.forename: K
authors.initials: K
authors.lastname: Hyoudou
authors.forename: S
authors.initials: S
authors.lastname: Kondo
authors.forename: T
authors.initials: T
authors.lastname: Kobayashi
authors.forename: J
authors.initials: J
authors.lastname: Ono
authors.forename: N
authors.initials: N
authors.lastname: Hamasaki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019963:Clinical Chemistry Tests / Q000592:standards*; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D011786:Quality Control; D012016:Reference Values; D013223:Statistics as Topic / Q000592:standards