[Effect of Sancai injection on red blood cell line in mice].
OBJECTIVE
To study the effective mechanism of Sancai Fensui Dan in mice.


METHODS
Sancai injection (SCI) was given to normal or anemia mice and their hemoglobin (Hb), red blood cell (RBC), reticulocyte (Ret) of peripheral blood, mitosis index (MI) of red cells, bone marrow nucleated cell (BMC) were measured. And the cultured hemopoietic progenitor cells of burst forming unit-erythroid (BFU-E) and colony forming unit-erythroid (CFU-E) were used to observe the hemopoiesis effect of SCI.


RESULTS
SCI could promote the increase of Hb, RBC, Ret, MI and BMC in anemia mice. At the presence of spleen cells or macrophages in peritoneal cavity, it could enhance the proliferation of BFU-E and CFU-E.


CONCLUSIONS
SCI could promote hemopoiesis by activating the hemo-opsonin.
Wang
L
L
Second Affiliated Hospital, Harbin Medical University, Harbin (150086).
Zhang
Z
Z
Qian
J
J
D000740:Anemia / Q000473:pathology*; D000818:Animals; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D015672:Erythroid Precursor Cells / Q000473:pathology*; D005260:Female; D007267:Injections; D008297:Male; D051379:Mice
D004365:Drugs, Chinese Herbal