title: Zinc-responsive dermatosis in dogs: 41 cases and literature review.
abstract: Forty-one cases of zinc-responsive dermatosis in the dog are described. The Siberian husky was the predominant breed affected. Periocular crusts were the most common clinical sign and parakeratosis was noted in the skin biopsy specimens of all dogs. Treatment with oral zinc ameliorated the clinical signs in most dogs, but cases necessitating other treatments such as parenteral zinc or retinoids are reported. The authors recommend a starting dose of 2-3 mg kg-1 elemental zinc per day in the treatment of this disorder.
authors.affiliation: Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California 95616, USA.
authors.forename: S D
authors.initials: SD
authors.lastname: White
authors.forename: P
authors.initials: P
authors.lastname: Bourdeau
authors.forename: R A
authors.initials: RA
authors.lastname: Rosychuk
authors.forename: B
authors.initials: B
authors.lastname: Cohen
authors.forename: T
authors.initials: T
authors.lastname: Bonenberger
authors.forename: K V
authors.initials: KV
authors.lastname: Fieseler
authors.forename: P
authors.initials: P
authors.lastname: Ihrke
authors.forename: P L
authors.initials: PL
authors.lastname: Chapman
authors.forename: P
authors.initials: P
authors.lastname: Schultheiss
authors.forename: G
authors.initials: G
authors.lastname: Zur
authors.forename: A
authors.initials: A
authors.lastname: Cannon
authors.forename: C
authors.initials: C
authors.lastname: Outerbridge
mesh_terms: D000284:Administration, Oral; D000818:Animals; D004283:Dog Diseases / Q000453:epidemiology* / Q000473:pathology / Q000517:prevention & control*; D004285:Dogs; D005260:Female; D005602:France / Q000453:epidemiology; D007114:Immunization / Q000662:veterinary*; D007557:Israel / Q000453:epidemiology; D008297:Male; D011996:Records / Q000662:veterinary; D012871:Skin Diseases / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary*; D014481:United States / Q000453:epidemiology; D019287:Zinc Sulfate / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D019287:Zinc Sulfate