[Cellular angiofibroma. A rare vulvar tumor. Report of a case].
Cellular angiofibroma is a rare tumor. We report a vulvar case in a 37 year old woman. This nodular, well circonscribed tumor consists of bland spindle cells, numerous thin or thick often hyalinized vessels and adipocytes. The stromal cells are positive for vimentin and negative for CD34, protein S100, smooth muscle actin, desmin, epithelial membrane antigen and cytokeratin. Cellular angiofibroma is a benign tumor that has to be differentiated from aggressive angiomyxoma, angiomyofibroblastoma, glomangiopericytoma, spindle cell lipoma, solitary fibrous tumor and perineurioma.
Colombat
M
M
Service d'Anatomie et Cytologie Pathologiques, CHU, 1 place Victor Pauchet, 80054 Amiens cedex 1, France.
Liard-Meillon
M E
ME
De Saint-Maur
P
P
Sevestre
H
H
Gontier
M F
MF
D000199:Actins / Q000032:analysis; D000328:Adult; D018322:Angiofibroma / Q000737:chemistry / Q000473:pathology*; D018952:Antigens, CD34 / Q000032:analysis; D003893:Desmin / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007633:Keratins / Q000032:analysis; D018396:Mucin-1 / Q000032:analysis; D009418:S100 Proteins / Q000032:analysis; D017154:Stromal Cells / Q000737:chemistry / Q000473:pathology; D014746:Vimentin / Q000032:analysis; D014846:Vulvar Neoplasms / Q000737:chemistry / Q000473:pathology*
D000199:Actins; D018952:Antigens, CD34; D003893:Desmin; D018396:Mucin-1; D009418:S100 Proteins; D014746:Vimentin; D007633:Keratins