title: Bipolar disorder.
abstract: Bipolar disorder (manic-depressive illness) is a common, recurrent, and severe psychiatric disorder that affects 1% to 3% of the US population. The illness is characterized by episodes of mania, depression, or mixed states (simultaneously occurring manic and depressive symptoms). Bipolar disorder frequently goes unrecognized and untreated for many years without clinical vigilance. New screening tools have been developed to assist physicians in making the diagnosis. Fortunately, several medications are now available to treat the acute mood episodes of bipolar disorder and to prevent further episodes with maintenance treatment.
authors.affiliation: Department of Psychiatry, Biological Psychiatry Program, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
authors.forename: P E
authors.initials: PE
authors.lastname: Keck
authors.forename: S L
authors.initials: SL
authors.lastname: McElroy
authors.forename: L M
authors.initials: LM
authors.lastname: Arnold
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D018692:Antimanic Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000145:classification / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D008094:Lithium / Q000627:therapeutic use; D008403:Mass Screening / Q000379:methods; D011613:Psychotherapy; D012008:Recurrence; D012106:Research; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology
chemical_list: D000927:Anticonvulsants; D000928:Antidepressive Agents; D018692:Antimanic Agents; D014150:Antipsychotic Agents; D008094:Lithium