Skin involvement as the first manifestation of systemic aspergillosis in patients after allogeneic hematopoietic cell transplantation.
Skin involvement due to a systemic infection with Aspergillus species in the course of allogeneic hematopoietic cell transplantation is extremely rare. We report the clinical course of two patients with hematologic malignancies who underwent allogeneic hematopoietic cell transplantation (HCT) and developed disseminated skin involvement as the first clinical symptom of a proven systemic Aspergillus infection.
Schimmelpfennig
C
C
Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus an der TU Dresden, Fetscher Str. 74, 01307 Dresden, Germany.
Naumann
R
R
Zuberbier
T
T
Ordemann
R
R
Baurmann
H
H
Beyer
J
J
Siegert
W
W
Bornhäuser
M
M
Ehninger
G
G
D000328:Adult; D001228:Aspergillosis / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D017809:Fatal Outcome; D019337:Hematologic Neoplasms / Q000150:complications / Q000628:therapy; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D016867:Immunocompromised Host / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D012871:Skin Diseases / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D014184:Transplantation, Homologous / Q000009:adverse effects