Genetic and environmental influences on anorexia nervosa syndromes in a population-based twin sample.
BACKGROUND
Genetic and environmental influences on broadly-defined anorexia nervosa (AN) syndrome were examined in a population-based twin sample.


METHODS
AN syndrome was assessed in 672 female 17 year-old twins using structured interviews and a self-report questionnaire.


RESULTS
Twenty-six probands with AN syndrome were identified. Biometrical model-fitting analyses indicated that genetic and non-shared environmental factors accounted for 74% and 26% of the variance in AN syndrome, respectively.


CONCLUSIONS
Findings support previous research indicating significant genetic and non-shared environmental influences on AN syndromes.
Klump
K L
KL
Department of Psychology, Michigan State University, East Lansing, USA.
Miller
K B
KB
Keel
P K
PK
McGue
M
M
Iacono
W G
WG
D000293:Adolescent; D000856:Anorexia Nervosa / Q000209:etiology / Q000235:genetics*; D004777:Environment; D005260:Female; D006801:Humans; D012044:Regression Analysis; D012307:Risk Factors