title: Colposcopically directed biopsy findings in the young female.
abstract: OBJECTIVE
  To evaluate the colposcopic findings of cervical alterations in the young sexually active female.
  
  
  METHODS
  Colposcopic examination and follow-up of 51 young sexually active females aged 15-20 yr was conducted due to abnormal cytology or a suspicious abnormality of the cervix. The study was conducted at the Colposcopy Units of the 1(st) and 2(nd) Departments of Obstetrics and Gynecology, University of Athens, Greece. ONTERVENTIONS: Colposcopic examination, LEEP, conization.
  
  
  METHODS
  Biopsy, human papillomavirus (HPV) typing.
  
  
  RESULTS
  Colposcopic examinations were within normal limits in 8 of 51 (15.7%) cases. Cervical alterations were related to HPV infection in 14 cases (27.4%), to cervical intraepithelial neoplasia (CIN) I in 15 (29.4%) cases, to CIN II in 13 (25.5%) cases, and to CIN III in 1 (2.0%) case. Of all CIN I cases, 8 of 15 (53.3%) were HPV positive, and HPV type 11, 16, 18, 31, 33, and 11& 16 were found. In CIN II cases, 5 of 13 (38.4%) were HPV positive, and HPV type 11, 16, 18, and 11 & 31 were found. In the CIN III case, only HPV type 16 was found.
  
  
  CONCLUSIONS
  Our findings strongly confirm the necessity of obtaining cervicovaginal smears on all sexually active gynecologic and obstetric teenage patients. Colposcopy plays a major role in the evaluation of the cervix and in the treatment that should be given for any individual CIN lesion.
authors.affiliation: Colposcopy Units, 1st and 2nd Departments of Obstetrics and Gynecology, University of Athens, Athens, Greece.
authors.forename: E A
authors.initials: EA
authors.lastname: Hassan
authors.forename: G K
authors.initials: GK
authors.lastname: Creatsas
authors.forename: E S
authors.initials: ES
authors.lastname: Diakomanolis
authors.forename: G G
authors.initials: GG
authors.lastname: Sakellaropoulos
authors.forename: A J
authors.initials: AJ
authors.lastname: Rodolakis
authors.forename: S D
authors.initials: SD
authors.lastname: Konidaris
authors.forename: S P
authors.initials: SP
authors.lastname: Michalas
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior; D016497:Adolescent Health Services; D000328:Adult; D000367:Age Factors; D002584:Cervix Uteri / Q000473:pathology*; D003127:Colposcopy; D005260:Female; D006801:Humans; D008403:Mass Screening; D012725:Sexual Behavior; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis*