[Changes of plasma renin activity and angiotensin II levels in women with polycystic ovary syndrome].
OBJECTIVE
To investigate changes of plasma renin activity(PRA) and plasma angiotensin II (PANG II) in women with polycystic ovary syndrome(PCOS).


METHODS
We chose thirty PCOS women as trial group and thirty normal menstrual women as control. PRA and PANG II levels during follicularphase(FP) of the two groups were measured by radioimmunoassay.


RESULTS
PRA and PANG II increased in women with PCOS as compared with the normal FP. The increment of PRA and PANG II in PCOS women of high testosterone levels was correlated with serum luteinizing hormone/follicle-stimulating hormone and testosterone concentration.


CONCLUSIONS
The elevated PRA and PANG II suggest an enhanced functional activity of ovarian renin angiotensin system in PCOS, and which may play a role in the pathologenesis of PCOS.
Li
X
X
Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Shen
H
H
Ge
X
X
D000328:Adult; D000804:Angiotensin II / Q000097:blood*; D005260:Female; D006801:Humans; D011085:Polycystic Ovary Syndrome / Q000097:blood*; D012083:Renin / Q000097:blood*
D000804:Angiotensin II; D012083:Renin