Genetic analysis of brain imaging abnormalities.
A number of child psychiatric disorders have recently been associated with specific structural brain abnormalities. This article discusses the advantages of neuroimaging for genetic studies, such as clarifying etiologic heterogeneity and establishing pathophysiology. The advantages of twin or family designs for neuroimaging investigations are also discussed.
Botteron
K N
KN
Division of Child and Adolescent Psychiatry, Departments of Psychiatry and Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.
D000293:Adolescent; D001921:Brain / Q000002:abnormalities* / Q000473:pathology; D001925:Brain Damage, Chronic / Q000175:diagnosis / Q000235:genetics*; D002648:Child; D003952:Diagnostic Imaging; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000235:genetics*; D008957:Models, Genetic; D009415:Nerve Net / Q000473:pathology; D018433:Twin Studies as Topic