The neuropathology of multiple sclerosis.
This article reviews the pathology of multiple sclerosis in an attempt to allow the reader to better understand the pathogenesis of the lesions. The elements comprising the lesions are discussed in light of their pathogenic implications. Current ideas of classification are discussed, and wherever possible, correlations with clinical and imaging studies are drawn.
Ludwin
S K
SK
Department of Pathology, Queen's University, Kingston, Ontario, Canada K7L3N6.
D000818:Animals; D001369:Axons / Q000473:pathology; D001921:Brain / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008854:Microscopy, Electron; D009103:Multiple Sclerosis / Q000209:etiology / Q000473:pathology*; D009186:Myelin Sheath / Q000473:pathology; D009474:Neurons / Q000473:pathology