Does the antitumor adenovirus ONYX-015/dl1520 selectively target cells defective in the p53 pathway?
Dix
B R
BR
Cell Transformation Group, Department of Pathology, School of Medicine, University of Otago, Dunedin, New Zealand.
Edwards
S J
SJ
Braithwaite
A W
AW
D000256:Adenoviridae / Q000378:metabolism; D017501:Adenovirus E1B Proteins / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D009154:Mutation; D009369:Neoplasms / Q000378:metabolism / Q000628:therapy* / Q000821:virology; D014407:Tumor Cells, Cultured; D016159:Tumor Suppressor Protein p53 / Q000235:genetics / Q000378:metabolism*
D017501:Adenovirus E1B Proteins; D016159:Tumor Suppressor Protein p53