Homeostasis: a scavenger receptor for haemoglobin.
Recent studies have identified a macrophage-specific receptor for the clearance of haemoglobin-haptoglobin complexes, which protects the host against the toxicity of free haemoglobin.
Gordon
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Sir William Dunn School of Pathology, University of Oxford, South Parks Road, OX1 3RE, Oxford, UK. Siamon.Gordon@pathology.ox.ac.uk
D006454:Hemoglobins / Q000378:metabolism*; D006706:Homeostasis / Q000502:physiology*; D008565:Membrane Proteins; D011971:Receptors, Immunologic / Q000378:metabolism*; D018110:Receptors, Lipoprotein; D051116:Receptors, Scavenger; D051122:Scavenger Receptors, Class B
D006454:Hemoglobins; D008565:Membrane Proteins; D011971:Receptors, Immunologic; D018110:Receptors, Lipoprotein; D051116:Receptors, Scavenger; C454739:Scarb1 protein, mouse; D051122:Scavenger Receptors, Class B