Solid-state chemical methods to investigate the nature of calcified deposits.
Basics and application of three solid-state chemical techniques are presented that can be used to study calcified deposits, e.g., in atherosclerotic lesions: thermogravimetry (TG; giving the mineral content), X-ray diffractometry (XRD; identifying the mineral phase and giving its crystallinity), and X-ray absorption spectroscopy (EXAFS; allowing one to identify amorphous phases that do not show up in X-ray diffractometry).
Epple
M
M
Solid State Chemistry, Faculty of Chemistry, University of Bochum, 44780 Bochum, Germany. matthias.epple@ruhr-uni-bochum.de
D015502:Absorptiometry, Photon; D001161:Arteriosclerosis / Q000473:pathology*; D002114:Calcinosis / Q000473:pathology*; D018360:Crystallography, X-Ray; D006801:Humans; D009131:Muscle, Smooth, Vascular / Q000473:pathology; D011237:Predictive Value of Tests; D013818:Thermogravimetry; D014961:X-Ray Diffraction