The system VO2+ +oxidized glutathione: a potentiometric and spectroscopic study.
The equilibria in the system VO2+ +oxidized glutathione in aqueous solution have been studied in the pH range 2-11 by a combination of pH potentiometry and spectroscopy (EPR, visible absorption and circular dichroism). The results of the various methods are self-consistent and the equilibrium model includes the species MLH4, MLH3, MLH2, MLH, ML, MLH(-1), MLH(-2) and several hydrolysis products (where H4L denotes oxidized glutathione); individual formation constants and spectra are given. Plausible structures for each stoichiometry are discussed.
Pessoa
J C
JC
Centro Química Estrutural, Instituto Superior Técnico, Lisboa, Portugal. pcjpessoa@popsrv.ist.utl.pt
Tomaz
I
I
Kiss
T
T
Buglyó
P
P
D002942:Circular Dichroism; D004563:Electrochemistry; D004578:Electron Spin Resonance Spectroscopy; D005978:Glutathione / Q000737:chemistry* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D008024:Ligands; D015394:Molecular Structure; D010084:Oxidation-Reduction / Q000187:drug effects; D014638:Vanadates / Q000737:chemistry*
D008024:Ligands; D014638:Vanadates; D005978:Glutathione