title: Nitroderm TTS band application for pain after hemorrhoidectomy.
abstract: OBJECTIVE
  Anal sphincter spasm is believed to play an important role in pain after hemorrhoidectomy. We tested a different form of nitroglycerin: the Nitroderm TTS band. We investigated its efficacy on posthemorrhoidectomy pain and the relation between pain and anal resting pressure measured preoperatively and postoperatively.
  
  
  METHODS
  Thirty-eight hemorrhoid patients were divided into two groups: those with high anal resting pressure were classified as group A (n = 24) and those with low anal resting pressure were classified as group B (n = 14). After hemorrhoidectomy, Nitroderm TTS bands were placed into the anal canal in half of the patients in groups A and B (groups A-1 and B-1) and not in the remaining half (groups A-2 and B-2). Anal resting pressure measurement was repeated at the first day and third month postoperatively. Postoperative pain was assessed by linear analog scale, and analgesic consumption was recorded.
  
  
  RESULTS
  Preoperative anal resting pressure was 112.0 (range, 95-140) cm H2O in group A-1 and 110.6 (range, 96-138) cm H2O in group A-2. The difference was insignificant. However, on the first postoperative day, anal resting pressures were 88.7 (range, 75-115) and 110.9 (range, 92-135) cm H2O (P = 0.0001), and at the third month, they were 76.5 (range, 70-100) and 78.0 (range, 70-105) cm H2O, respectively (P = 0.690). Postoperative pain scores were significantly lower in group A-1 than group A-2 (P = 0.0001). In the low-pressure groups (B-1 and B-2), anal resting pressures before surgery, on the first postoperative day, and at the third month postoperatively were 70.4 (range, 56-76), 67.4 (range, 50-75), and 67.2 (range, 55-74) cm H2O in group B-1 and 69.8 (range, 58-76), 70.2 (range, 60-76), and 68.4 (range, 60-74) cm H2O in group B-2. The differences were insignificant (P > or = 0.660). The differences between pain scores in these groups were also insignificant (P > or = 0.160).
  
  
  CONCLUSIONS
  Nitroderm TTS bands effectively reduced anal resting pressure and relieved pain in patients with high preoperative anal resting pressure.
authors.affiliation: Harran University School of Medicine, Departments of General Surgery and Pharmacology, Sanliurfa, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Coskun
authors.forename: S A
authors.initials: SA
authors.lastname: Duzgun
authors.forename: A
authors.initials: A
authors.lastname: Uzunkoy
authors.forename: M
authors.initials: M
authors.lastname: Bozer
authors.forename: O
authors.initials: O
authors.lastname: Aslan
authors.forename: B
authors.initials: B
authors.lastname: Canbeyli
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D001003:Anal Canal / Q000502:physiology / Q000601:surgery; D005260:Female; D006484:Hemorrhoids / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage* / Q000494:pharmacology; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D011183:Postoperative Complications / Q000517:prevention & control; D011312:Pressure; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000008:administration & dosage* / Q000494:pharmacology
chemical_list: D014665:Vasodilator Agents; D005996:Nitroglycerin