Magnetic field-like fluid circulation of a porous orifice tube and its relevance to the capillary-interstitial fluid circulation: preliminary report.
In 1886, Starling proposed a hypothesis for the capillary-interstitial fluid transfer in which capillary filtration is attributed to arterial pressure, based on Poiseuille's work in long uniform tubes. In 1967-8, the precapillary sphincter, pores and negative interstitial pressure were reported. In 1984, clinical observations inconsistent with Starling's hypothesis prompted a physical study to verify pressure dynamics in a porous orifice (G) tubes. Results demonstrate that, unlike in Poiseuille's tube, a fluid passing inside the lumen of the G tube exerts a negative energy pressure gradient on its wall; most negative over its proximal part causing inflow of fluid by suction and positive over its distal part causing fluid outflow. A net negative pressure gradient also occurs in a surrounding chamber C, causing fluid to flow in an opposite direction to lumen flow. An autonomous dynamic magnetic field-like G-C circulation occurred between lumen and surrounding fluid compartments. Reviewed literature support the contention that this sole phenomenon adequately explains the capillary-interstitial fluid transfer under both physiological and pathological haemodynamic conditions.
Ghanem
A N
AN
King Khalid Hospital, Najran, Kingdom of Saudi Arabia. an_ghanem@yahoo.com
D000818:Animals; D001775:Blood Circulation / Q000502:physiology*; D002196:Capillaries / Q000502:physiology*; D005110:Extracellular Space / Q000502:physiology*; D006801:Humans; D008280:Magnetics; D008955:Models, Cardiovascular