title: Presence of a simple tandem repeat in the ITS1 region of the Xylariales.
abstract: A Simple Tandem Repeat sequence of 11 nucleotides has been found in the ITS1 region of the rDNA of members of Order Xylariales. The number of repetitions detected ranged from one to six, and they could be found in pure tandem or interspersed. The same core sequences have also been found in DNA from other organisms, although usually not repeated in tandem. These repetitions could have been generated by slipped strand mispairing. The presence of this sequence increases the normal rate of divergence in the ITS1 of the Xylariales. The phylogenetic implications of the presence of this sequence in the molecular taxonomy of Xylariales are also discussed.
authors.affiliation: Centro de Investigación Básica, Natural Products Drug Discovery, Merck Sharp & Dohme Research Laboratories, Merck Sharp, & Dohme de España, S. A. Josefa Valcárcel 38. 28027, Madrid, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Platas
authors.forename: J
authors.initials: J
authors.lastname: Acero
authors.forename: J A
authors.initials: JA
authors.lastname: Borkowski
authors.forename: V
authors.initials: V
authors.lastname: González
authors.forename: M A
authors.initials: MA
authors.lastname: Portal
authors.forename: V
authors.initials: V
authors.lastname: Rubio
authors.forename: J
authors.initials: J
authors.lastname: Sánchez-Ballesteros
authors.forename: O
authors.initials: O
authors.lastname: Salazar
authors.forename: F
authors.initials: F
authors.lastname: Peláez
mesh_terms: D001203:Ascomycota / Q000737:chemistry / Q000235:genetics*; D001483:Base Sequence; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics*; D021903:DNA, Ribosomal Spacer / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid; D020080:Tandem Repeat Sequences / Q000235:genetics*
chemical_list: D004271:DNA, Fungal; D021903:DNA, Ribosomal Spacer