Congenital self-healing reticulohistiocytosis with eye involvement.
Congenital self-healing reticulohistiocytosis (CSHR) represents the benign end of the spectrum of Langerhans cell histiocytoses, with spontaneous resolution of lesions within the first year of life. However, involvement of organ systems other than the skin has been described occasionally and recurrence of disease at sites distant from the skin has been documented. We report a case of CSHR with eye involvement that spontaneously resolved concurrent with resolution of skin lesions. Because multiple organ systems can be involved and recurrences are possible, long-term follow-up of these patients is indicated.
Zaenglein
A L
AL
Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York 10016, USA.
Steele
M A
MA
Kamino
H
H
Chang
M W
MW
D018949:Antigens, CD1 / Q000032:analysis; D003937:Diagnosis, Differential; D005128:Eye Diseases / Q000473:pathology*; D005260:Female; D015616:Histiocytosis, Non-Langerhans-Cell / Q000151:congenital / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007231:Infant, Newborn; D012075:Remission, Spontaneous; D009418:S100 Proteins / Q000032:analysis; D012867:Skin / Q000737:chemistry / Q000473:pathology
D018949:Antigens, CD1; C419393:CD1a antigen; D009418:S100 Proteins