title: Clinical features of paragonimiasis cases recently found in japan: parasite-specific immunoglobulin M and G antibody classes.
abstract: We retrospectively analyzed clinical features in 30 patients who were referred to our laboratory and given a diagnosis of Paragonimus westermani infection in 1999. Our results indicate that pleurisy with eosinophilia and dominant immunoglobulin (Ig) M antibody are characteristic features of the early stage of paragonimiasis, whereas IgG antibody is dominant in the late stage. Thus, in addition to tests for parasite-specific IgG antibody, tests for IgM-class antibody should always be considered for patients with pleurisy in whom paragonimiasis is suspected.
authors.affiliation: Department of Parasitology, Miyazaki Medical College, Miyazaki, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Nakamura-Uchiyama
authors.forename: D N
authors.initials: DN
authors.lastname: Onah
authors.forename: Y
authors.initials: Y
authors.lastname: Nawa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood* / Q000145:classification; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000145:classification; D007075:Immunoglobulin M / Q000097:blood / Q000145:classification; D007564:Japan; D008297:Male; D008875:Middle Aged; D010237:Paragonimiasis / Q000097:blood / Q000276:immunology* / Q000469:parasitology / Q000503:physiopathology; D010238:Paragonimus / Q000276:immunology; D012189:Retrospective Studies
chemical_list: D000909:Antibodies, Helminth; D007074:Immunoglobulin G; D007075:Immunoglobulin M