Functional magnetic resonance imaging and evoked potential correlates of conscious and unconscious vision in parietal extinction patients.
We describe recent functional magnetic resonance imaging (fMRI) and event-related potential (ERP) studies of visual extinction in patients with right parietal damage who can detect isolated visual stimuli on either side, yet often miss contralesional (left) stimuli during bilateral stimulation. We consider the neural fate of such extinguished visual stimuli and how neural responses differ for consciously detected versus extinguished stimuli. fMRI findings indicate that extinguished stimuli evoke activity in striate and ventral extrastriate visual cortex, despite escaping awareness. Activations for extinguished stimuli can be found even in category-specific (face-responsive) areas of the fusiform gyrus. On the other hand, activations in visual cortex are stronger for consciously detected versus extinguished stimuli, with parietal and frontal areas of the intact left hemisphere also implicated in this comparison. Recent ERP data likewise suggest differential neural responses for consciously detected versus extinguished stimuli. We discuss these findings in relation to current speculations about the neural basis of conscious and unconscious perception.
Driver
J
J
Institute of Cognitive Neuroscience, University College London, UK. j.driver.ucl.ac.uk
Vuilleumier
P
P
Eimer
M
M
Rees
G
G
D001288:Attention / Q000502:physiology*; D001364:Awareness / Q000502:physiology*; D001931:Brain Mapping; D004292:Dominance, Cerebral / Q000502:physiology; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005108:Extinction, Psychological / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D010296:Parietal Lobe / Q000503:physiopathology*; D010468:Perceptual Disorders / Q000503:physiopathology*; D014795:Visual Pathways / Q000503:physiopathology; D014796:Visual Perception / Q000502:physiology*