title: The coatomer of Trypanosoma brucei.
abstract: Coatomer is a multisubunit complex involved in trafficking of vesicles between the endoplasmatic reticulum and the Golgi apparatus. From sequence homologies, all seven subunits, alpha-, beta-, beta'-, gamma-, delta-, epsilon-, and zeta-COP, are encoded in the genome of Trypanosoma brucei. The complete predicted amino-acid sequences of beta-, beta'-, and zeta-COP show only 20-30% identity with higher eucaryotic homologues. The trypanosome coatomer complex was partially purified using a procedure similar to that used for bovine coatomer.
authors.affiliation: Zentrum für Molekulare Biologie (ZMBH), Im Nevenheimer Feld 282, 69120, Heidelberg, Germany.
authors.forename: A G
authors.initials: AG
authors.lastname: Maier
authors.forename: H
authors.initials: H
authors.lastname: Webb
authors.forename: M
authors.initials: M
authors.lastname: Ding
authors.forename: M
authors.initials: M
authors.lastname: Bremser
authors.forename: M
authors.initials: M
authors.lastname: Carrington
authors.forename: C
authors.initials: C
authors.lastname: Clayton
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D020756:Coatomer Protein / Q000737:chemistry / Q000235:genetics* / Q000302:isolation & purification* / Q000378:metabolism; D016054:DNA, Protozoan / Q000032:analysis / Q000235:genetics; D005455:Fluorescent Antibody Technique; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D014346:Trypanosoma brucei brucei / Q000235:genetics / Q000378:metabolism*
chemical_list: D020756:Coatomer Protein; D016054:DNA, Protozoan