title: Coincidence of cytomegalovirus retinitis and central retinal vein occlusion in a patient with hemophilia B and AIDS.
abstract: A 37-year-old man with hemophilia B, acquired immunodeficiency syndrome, and a unilateral cytomegalovirus retinitis developed a central retinal vein occlusion. This vascular complication occurred despite effective antiviral drug treatment with improvement of the fundus and despite decreased blood coagulability due to hemophilia B. Additional analyses of thrombophilic parameters did not reveal hints of systemic thrombophilia, suggesting that toxic and inflammatory effects of cytomegalovirus itself were responsible for the ophthalmologic aggravation.
authors.affiliation: Department of Medicine, University of Muenster, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Schiemann
authors.forename: M
authors.initials: M
authors.lastname: Steins
authors.forename: V
authors.initials: V
authors.lastname: Knospe
authors.forename: M
authors.initials: M
authors.lastname: Riedasch
authors.forename: W
authors.initials: W
authors.lastname: Domschke
authors.forename: R
authors.initials: R
authors.lastname: Stoll
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications*; D000328:Adult; D017726:Cytomegalovirus Retinitis / Q000150:complications*; D002836:Hemophilia B / Q000821:virology*; D006801:Humans; D008297:Male; D012170:Retinal Vein Occlusion / Q000175:diagnosis / Q000821:virology*