title: Merits and demerits of operative procedure to the trachea in patients with differentiated thyroid cancer.
abstract: Local radical thyroidectomy, including cervical lymph node dissection and combined circumferential resection of the trachea, has been performed over the past 20 years in 31 patients with differentiated cancer invading the trachea. The 5- and 10-year survival rates for these patients were 77.4% and 66.7%, respectively. In 19 of the 31 (61%) cases the recurrent nerve was resected because of direct cancer invasion. Bilateral recurrent nerve palsy occurred in 12 patients, 3 of whom were managed postoperatively using a T-shaped tube for preservation of the larynx. Hoarseness remained in 21 patients. In two patients with recurrent cancer invasion of the larynx, partial laryngectomy and hemilaryngectomy were performed, and reconstruction was done using ear cartilage without postoperative dyspnea or dysphagia. Parathyroid function is an important factor in regard to the quality of life of patients. In 22 patients at least one of the parathyroids was preserved. Postoperative calcium administration was necessary in 14 patients. Our long-term observations indicate that local radical thyroidectomy with combined resection of the trachea can serve as a useful treatment for advanced differentiated cancer invading the airway.
authors.affiliation: Department of Surgery and Pathology, Osaka Police Hospital, 10-31 Kitayama-cho, Tennoji-ku, Osaka 543-0035, Japan. master@oph.gr.jp
authors.forename: K
authors.initials: K
authors.lastname: Nakao
authors.forename: K
authors.initials: K
authors.lastname: Kurozumi
authors.forename: S
authors.initials: S
authors.lastname: Fukushima
authors.forename: M
authors.initials: M
authors.lastname: Nakahara
authors.forename: M
authors.initials: M
authors.lastname: Tsujimoto
authors.forename: T
authors.initials: T
authors.lastname: Nishida
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D013964:Thyroid Neoplasms / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods*; D014132:Trachea / Q000473:pathology / Q000601:surgery*