Neointima suppression in rat carotid allografts by FTY720 combined with a small fixed cyclosporine dose is related to a diminution of the peripheral lymphocyte count.
Nikolova
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Novartis Pharma Research, Novartis Pharma AG, Basel, Switzerland.
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D000818:Animals; D002339:Carotid Arteries / Q000502:physiology / Q000637:transplantation*; D016572:Cyclosporine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D000068876:Fingolimod Hydrochloride; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007958:Leukocyte Count; D018655:Lymphocyte Count; D011409:Propylene Glycols / Q000627:therapeutic use*; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D013110:Sphingosine / Q000031:analogs & derivatives; D013997:Time Factors; D014184:Transplantation, Homologous / Q000276:immunology*; D017539:Tunica Intima / Q000502:physiology / Q000637:transplantation*
D007166:Immunosuppressive Agents; D011409:Propylene Glycols; D016572:Cyclosporine; D000068876:Fingolimod Hydrochloride; D013110:Sphingosine