[Isometric contractions of the myocardium: mathematic modeling].
A mathematical model describing a single contraction of a cardiac muscle strip under isometric conditions is proposed. The adequacy of the model was checked in experiments on cardiac strips from patients with chronic coronary insufficiency. It was shown that the contraction-relaxation cycle is rather completely characterized by the parameters characterizing the association-dissociation kinetics of actomyosin bridges.
Timofeev
V Iu
VIu
Siberian State Medical University, Tomsk, Russia.
Afanas'ev
S A
SA
D006801:Humans; D066298:In Vitro Techniques; D007537:Isometric Contraction; D008297:Male; D008954:Models, Biological; D009126:Muscle Relaxation; D009200:Myocardial Contraction