Regional tissue metabolism during open or endovascular abdominal aortic aneurysm surgery.
OBJECTIVE
to investigate differences in regional tissue metabolism between open and endovascular aneurysm repair utilising a microdialysis technique.


METHODS
eight patients receiving endovascular stent grafts (STENT) and six patients undergoing open aortic surgery (OPEN) for abdominal aortic aneurysms were studied prospectively but non-randomised.


METHODS
microdialysis catheters placed subcutaneously in the pectoral and calf region, respectively.


RESULTS
microdialysate glucose levels increased in the OPEN group on the day of surgery. Microdialysate lactate levels increased transiently in the leg in the STENT group. In the OPEN group lactate increased in the leg after aortic cross-clamping. Glycerol decreased in the pectoral region in the STENT group after surgery, but remained elevated in the OPEN group.


CONCLUSIONS
we found indications that the metabolic impact of the two aortic procedures differ. This may be of clinical importance when selecting patients for either open aortic surgery or endovascular stentgrafting.
Metzsch
C
C
Department of Anaesthesiology and Intensive Care, Lund University Hospital, Lund, Sweden.
Lundberg
J
J
Norgren
L
L
D000273:Adipose Tissue / Q000378:metabolism; D000368:Aged; D000704:Analysis of Variance; D017544:Aortic Aneurysm, Abdominal / Q000378:metabolism* / Q000601:surgery*; D005260:Female; D005947:Glucose / Q000378:metabolism; D005990:Glycerol / Q000378:metabolism; D006801:Humans; D019344:Lactic Acid / Q000378:metabolism; D008297:Male; D017551:Microdialysis; D008875:Middle Aged; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D015607:Stents
D019344:Lactic Acid; D005947:Glucose; D005990:Glycerol