title: The role of radiotherapy and limb-conserving surgery in the management of soft-tissue sarcomas in adults.
abstract: The treatment of soft-tissue sarcomas has undergone significant changes over the past several decades. Previously, patients were often treated with surgery alone, which frequently necessitated amputation of the affected extremity. Less extensive, limb-sparing operations combined with adjuvant irradiation are now feasible for most patients without compromising the likelihood of cure.
authors.affiliation: Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida, USA.
authors.forename: J T
authors.initials: JT
authors.lastname: Parsons
authors.forename: R A
authors.initials: RA
authors.lastname: Zlotecki
authors.forename: K A
authors.initials: KA
authors.lastname: Reddy
authors.forename: T P
authors.initials: TP
authors.lastname: Mitchell
authors.forename: R B
authors.initials: RB
authors.lastname: Marcus
authors.forename: M T
authors.initials: MT
authors.lastname: Scarborough
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology / Q000601:surgery; D012509:Sarcoma / Q000532:radiotherapy* / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000532:radiotherapy* / Q000601:surgery*