A combination of KH1060, a vitamin D(3) analogue, and cyclosporin prevents early graft failure and prolongs graft survival of xenogeneic islets in nonobese diabetic mice.
Gysemans
C
C
Department of Experimental Medicine and Endocrinology (LEGENDO), Leuven, Belgium.
Waer
M
M
Laureys
J
J
Bouillon
R
R
Mathieu
C
C
D000818:Animals; D002117:Calcitriol / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D016572:Cyclosporine / Q000627:therapeutic use*; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery*; D004359:Drug Therapy, Combination; D005260:Female; D006084:Graft Rejection / Q000517:prevention & control; D006085:Graft Survival / Q000187:drug effects / Q000276:immunology*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D016688:Mice, Inbred NOD; D051381:Rats; D011913:Rats, Inbred BB; D013997:Time Factors; D014183:Transplantation, Heterologous / Q000276:immunology*
D007166:Immunosuppressive Agents; C074279:KH 1060; D016572:Cyclosporine; D002117:Calcitriol