title: [Application of VNTR D17S30 locus polymorphism in the paternity test].
abstract: A sensitive and rapid PCR-based technique was adopted to genotype the VNTR D17S30 locus. It was confirmed through the genetic analysis of 20 normal families that the inheritance of D17S30 locus coincides with Mendelian law as simple co-dominant. Retrospective analysis of 100 paternity cases demonstrated that D17S30 locus could be used in forensic paternity test in our country. The exclusion probability estimated from allele frequencies of D17S30 locus (74.04%) does not differ significantly from the observed rate of exclusion (80.00%) in these cases. In all excluded paternity cases there are two in which the exclusion evidence is solely provided by the D17S30 locus.
authors.affiliation: Immuno-genetics Laboratory, Shanghai Institute of Blood Transfusion, Shanghai Blood Center, Shanghai 200051.
authors.forename: M
authors.initials: M
authors.lastname: Feng
authors.forename: Z
authors.initials: Z
authors.lastname: Feng
authors.forename: Q
authors.initials: Q
authors.lastname: Lu
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: Y
authors.initials: Y
authors.lastname: Yang
authors.forename: Y
authors.initials: Y
authors.lastname: Ji
authors.forename: R
authors.initials: R
authors.lastname: Chen
mesh_terms: D002886:Chromosomes, Human, Pair 17; D005554:Forensic Medicine; D006801:Humans; D018598:Minisatellite Repeats; D010334:Paternity; D016133:Polymerase Chain Reaction / Q000379:methods; D012189:Retrospective Studies