title: Acute disseminated encephalomyelitis in autoimmune hemolytic anemia.
abstract: A 16-year-old female with chronic autoimmune hemolytic anemia is presented. She was diagnosed with acute disseminated encephalomyelitis by clinical findings and magnetic resonance imaging (MRI), and the condition occurred after a systemic infection with Cryptococcus neoformans. Intravenous immunoglobulin therapy remarkably improved the patient's neurologic deficit and resolved abnormalities evidenced on MRI. To our knowledge, this report is the first of a pediatric patient with autoimmune hemolytic anemia complicated by acute disseminated encephalomyelitis that developed after an apparently successful treatment of cryptococcal meningitis.
authors.affiliation: Divisions of Hematology and Oncology, Chang Gung Children's Hospital, Taoyuan, Taiwan.
authors.forename: T H
authors.initials: TH
authors.lastname: Jaing
authors.forename: K L
authors.initials: KL
authors.lastname: Lin
authors.forename: C H
authors.initials: CH
authors.lastname: Chiu
authors.forename: W C
authors.initials: WC
authors.lastname: Lo
authors.forename: P L
authors.initials: PL
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications*; D001921:Brain / Q000473:pathology; D002908:Chronic Disease; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging; D016919:Meningitis, Cryptococcal / Q000188:drug therapy* / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous