title: Transmembrane ion conductance by an acyclic bolaamphiphile.
abstract: [reaction in text] An acyclic bolaamphiphile forms ion channels in vesicles and planar bilayer membranes that are closely similar to the channels formed by related bismacrocyclic compounds. Thus the function of these ion channels does not depend on synthetically difficult macrocyclic subunits.
authors.affiliation: Department of Chemistry, University of Victoria, Victoria, BC, Canada V8W 3P6. tmf@uvic.ca
authors.forename: T M
authors.initials: TM
authors.lastname: Fyles
authors.lastname: Hu Cw
authors.forename: R
authors.initials: R
authors.lastname: Knoy
mesh_terms: D001692:Biological Transport; D007473:Ion Channels / Q000737:chemistry* / Q000378:metabolism; D008051:Lipid Bilayers / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008566:Membranes / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D015394:Molecular Structure; D010713:Phosphatidylcholines / Q000737:chemistry; D013329:Structure-Activity Relationship; D013501:Surface-Active Agents / Q000737:chemistry
chemical_list: D007473:Ion Channels; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D013501:Surface-Active Agents; C021016:1,2-diphytanoylphosphatidylcholine