[Prenatal diagnosis and management in VACTERL association].
In terms of the VACTERL-Association we are dealing with a non-random association of malformations following a defect during mesodermal development of embryogenesis due to a variety of causes. We report on three cases with VACTERL-type malformations diagnosed by prenatal ultrasound presenting cardial defects, renal abnormalities, single umbilical arteries and esophageal stenosis. We present sonographical, clinical and autopsy findings and discuss the pathogenesis of VACTERL-Association as a defect of mesenchymal development in early embryogenesis.
Tercanli
S
S
Universitäts-Frauenklinik Basel.
Troeger
C
C
Fahnenstich
H
H
Hösli
I
I
Holzgreve
W
W
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging* / Q000473:pathology; D000025:Abortion, Eugenic; D000328:Adult; D004940:Esophageal Stenosis / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D016216:Ultrasonography, Prenatal; D014469:Umbilical Arteries / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology