Biomaterials integrated with electronic elements: en route to bioelectronics.
Bioelectronics is a progressing interdisciplinary research field that involves the integration of biomaterials with electronic transducers, such as electrodes, field-effect-transistors or piezoelectric crystals. Surface engineering of biomaterials, such as enzymes, antigen-antibodies or DNA on the electronic supports, controls the electrical properties of the biomaterial-transducer interface and enables the electronic transduction of biorecognition events, or biocatalyzed transformation, on the transducers. Bioelectronic sensing devices, biosensors of tailored sensitivities and specificities, are being developed.
Willner
I
I
Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel. willnea@vms.huji.ac.il
Willner
B
B
D000937:Antigen-Antibody Reactions; D001672:Biocompatible Materials; D015374:Biosensing Techniques; D004247:DNA / Q000032:analysis*; D004581:Electronics / Q000379:methods* / Q000639:trends; D004798:Enzymes
D001672:Biocompatible Materials; D004798:Enzymes; D004247:DNA