title: HIV-1 and hepatitis B virus infections in adolescents lodged in security institutes of Buenos Aires.
abstract: The goal of this study was to determine the prevalence of human immunodeficiency virus type 1 (HIV-1) and hepatitis B virus (HBV) infections in street youth lodged in security institutes, from February 1992 to March 1995, to correlate these infections with nontherapeutic drug use, and to compare these results with a previous study done in a similar population. A total of 1460 white adolescents, 276 females and 1184 males, were enrolled (mean age 16.6 years). Prevalence of HIV-1 was 4.58% and of HBV was 6.78%. The prevalence of dual HIV-1/HBV infection was 1.91%; the prevalence of HBV infection was significantly higher in HIV-positive subjects (p < 0.0000000, chi 2 = 136.17, OR = 13.37) than in those not infected with HIV-1. Prevalences were higher in males. Intravenous drug addiction proved to be a significant risk factor for both viruses (HIV-1, p < 0.0000000, chi 2 = 171.34, OR = 16.84; HBV, p = 0.000044, chi 2 = 16.67, OR = 3.17); 6.43% of the total population were intravenous drug users. Comparison of the current results with our previous study (1989-1992) showed that the prevalence of HIV-1, HBV, and concurrent HIV/HBV as well as intravenous drug addiction has decreased significantly in our current cohort (chi 2 = 134.85, p < 0.0000000; chi 2 = 126.62, p < 0.0000000; chi 2 = 110.05, p < 0.0000000; and chi 2 = 158.3, p < 0.0000000) respectively. Progress appears to have been made in the fight against acquired immunodeficiency syndrome (AIDS), and promising results have been obtained. However, if further viral spread is to be avoided, the emphasis on prevention should be energetically maintained.
authors.affiliation: Department of Microbiology, University of Buenos Aires School of Medicine, Argentina.
authors.forename: M M
authors.initials: MM
authors.lastname: Avila
authors.forename: E
authors.initials: E
authors.lastname: Casanueva
authors.forename: C
authors.initials: C
authors.lastname: Piccardo
authors.forename: D
authors.initials: D
authors.lastname: Liberatore
authors.forename: G
authors.initials: G
authors.lastname: Cammarieri
authors.forename: M
authors.initials: M
authors.lastname: Cervellini
authors.forename: I
authors.initials: I
authors.lastname: Gojman
authors.forename: O
authors.initials: O
authors.lastname: Libonatti
mesh_terms: D000293:Adolescent; D000328:Adult; D001118:Argentina / Q000453:epidemiology; D002648:Child; D005260:Female; D015658:HIV Infections / Q000453:epidemiology*; D015528:HIV Seroprevalence; D015497:HIV-1; D006509:Hepatitis B / Q000453:epidemiology*; D018453:Homeless Youth; D006801:Humans; D007604:Juvenile Delinquency; D008297:Male; D015995:Prevalence; D011330:Prisons; D012307:Risk Factors; D015819:Substance Abuse, Intravenous / Q000150:complications; D014504:Urban Health