Primary nephrectomy for emergency: a rare event in the International Society of Paediatric Oncology Nephroblastoma Trial and Study no. 9.
Experience of the International Society of Paediatric Oncology (SIOP) Trials and Studies indicates that the preoperative chemotherapy in Wilms' tumour improves stage distribution, decreases complication rate and reduces postoperative treatment. However, some situations may lead to prompt primary surgery. The aim of the study is to assess reasons leading to primary emergency nephrectomy. Records of 720 patients with non-metastatic unilateral nephroblastoma who were registered in the SIOP Trial and Study 9 were reviewed. Twenty-four (3%) cases of primary emergency nephrectomy were identified. Reasons leading to emergency nephrectomy were massive bleedings from ruptured tumours in 13 patients, suspicion of an "acute abdomen" in 7, bowel occlusion in 2 and other in 2. Postoperative treatment included radiotherapy in 71% of cases and anthracyclines in 92%. Complications were frequent and happened in 25% of patients, the outcome however, was favourable and 22 of 24 patients are alive (from 9 to 79 months). The 7 patients with a suspicion of an "acute abdomen" probably constitute the group which could have been markedly reduced if adequately diagnosed and observed prior to surgery.
Godziński
J
J
Department of Paediatric Surgery, Marciniak Hospital, Wrocław, Poland. jgodzin@dilnet.wroc.pl
Weirich
A
A
Tournade
M F
MF
Gauthier
F
F
Buerger
D
D
Moorman-Voestermans
C G
CG
de Kraker
J
J
Voute
P
P
Ludwig
R
R
Sawicz-Birkowska
K
K
Vujanić
G
G
Ducourtieux
M
M
D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004632:Emergency Medical Services; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D009392:Nephrectomy; D011183:Postoperative Complications; D012189:Retrospective Studies; D012422:Rupture, Spontaneous; D009396:Wilms Tumor / Q000150:complications / Q000473:pathology / Q000601:surgery*