title: Rupture of a previously normal spleen in association with enoxaparin: An unusual cause of shock.
abstract: We report the case of an adult male presenting in shock caused by spontaneous rupture of a pathologically normal spleen. One day before his presentation he had received a single subcutaneous injection of enoxaparin. This was the patient's only clearly identifiable risk factor for spontaneous splenic rupture. Nontraumatic splenic rupture should be included in the differential diagnosis of shock.
authors.affiliation: Division of Emergency Medicine, Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA.
authors.forename: M D
authors.initials: MD
authors.lastname: Burg
authors.forename: J J
authors.initials: JJ
authors.lastname: Dallara
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects*; D003937:Diagnosis, Differential; D017984:Enoxaparin / Q000009:adverse effects*; D006801:Humans; D007279:Injections, Subcutaneous; D007813:Laparotomy; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012769:Shock / Q000175:diagnosis / Q000209:etiology*; D013161:Splenic Rupture / Q000139:chemically induced* / Q000150:complications* / Q000601:surgery
chemical_list: D000925:Anticoagulants; D017984:Enoxaparin