[The change of salivary beta 2-microglobulin concentration in normal adults].
OBJECTIVE
To understand the influence of various physiological factors on the concentration of beta 2-microglobulin in saliva.


METHODS
We measured salivary beta 2-microglobulin concentration in 200 normal adults, from 21 year-old to 70 year-old, by means of radioactive immunoassay method.


RESULTS
We found, that there was no significant difference between males and females in salivary beta 2-m concentration, and salivary beta 2-m concentration was more significantly elevated in the adults above 50 year-old, compared with the adults from 21 year-old to 50 year-old. We also found, that there was no significant correlation between salivary beta 2-m concentration and serum beta 2-m concentration.


CONCLUSIONS
Our results suggested, that beta 2-m in saliva may be produced in oral cavity and salivary glands, and measurement of salivary beta 2-m concentration may offer a valuable method to diagnose lymphocytic infiltration disease in oral cavity or salivary glands.
Bu
Y
Y
PUMC Hospital, CAMS and PUMC, Beijing 100730.
Du
D
D
Zhao
Y
Y
D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D012016:Reference Values; D012463:Saliva / Q000737:chemistry*; D012737:Sex Factors; D001613:beta 2-Microglobulin / Q000032:analysis*
D001613:beta 2-Microglobulin