title: [Research on immunological activity of non-immunological cells of decidua in normal early pregnancy].
abstract: OBJECTIVE
  To investigate the immunological activity of non-immunological cells of decidua in normal early pregnancy.
  
  
  METHODS
  Harvest the supernatant from cultured non-immunological cells of decidua. Inspect the effects of the supernatant on transforming function of T cells, killing activity of natural killer cells, the IgG secretion of B cells and the interleukin-2 (IL-2) secretion by lymphocytes of human peripheral blood by radioimmunological assay (RIA).
  
  
  RESULTS
  The supernatant of the cultured non-immunological cells of decidua can inhibit the immunological function of T cells, natural killer cells and B cells to different extents, their maximum inhibiting ratio were 22.7%, 52.3% and 14.8% respectively, but there is no significant effect on the IL-2 secretion by lymphocytes.
  
  
  CONCLUSIONS
  The non-immunological cells of decidua in normal early pregnancy have immunological inhibiting function, which might contribute to prevent fetus from being expelled by maternal immunological system.
authors.affiliation: Zhujiang Hospital, First Military Medical, University, Guangzhou 510282.
authors.forename: D
authors.initials: D
authors.lastname: Hu
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
authors.forename: J
authors.initials: J
authors.lastname: Yan
mesh_terms: D002478:Cells, Cultured; D003656:Decidua / Q000166:cytology / Q000276:immunology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D007376:Interleukin-2 / Q000378:metabolism; D007694:Killer Cells, Natural / Q000276:immunology; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology*; D011247:Pregnancy; D011261:Pregnancy Trimester, First
chemical_list: D007074:Immunoglobulin G; D007376:Interleukin-2