The role of phenotypes (diagnoses) in genetic studies of attention-deficit/hyperactivity disorder and related child psychopathology.
The new medical genetics and its molecular, population, and statistical techniques offer a cadre of tools that will improve the child psychiatrist's ability to diagnose and treat children who exhibit emotional and behavioral disorders. To take advantage of these remarkable advances, child psychiatry must enhance the likelihood that scientific expeditions into gene discovery are informed by a taxonomy that meets the criteria of a genetic nosology. As the taxonomic approach is refined, there may be more success in identifying genetic and environmental risks for attention-deficit/hyperactivity disorder (ADHD).
Hudziak
J J
JJ
University of Vermont College of Medicine, Burlington, Vermont, USA. jhudziak@zoo.uvm.edu
D000293:Adolescent; D000342:Affective Symptoms / Q000175:diagnosis / Q000235:genetics*; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000235:genetics*; D002648:Child; D002653:Child Behavior Disorders / Q000175:diagnosis / Q000235:genetics*; D015897:Comorbidity; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D008297:Male; D010641:Phenotype; D011569:Psychiatric Status Rating Scales; D012931:Social Environment