Midlatency respiratory-related somatosensory activity and perception of oral pressure pulses in normal humans.
A direct relationship exists within subjects between midlatency features (<100 ms poststimulus) of respiratory-related evoked potentials and the perceived magnitude of applied oral pressure pulse stimuli. We evaluated perception in 18 normal subjects using cross-modality matching of applied pressure pulses via grip force and estimated mechanoafferent activity in these subjects by computing the global field power (GFP) from respiratory-related evoked potentials recorded over the right side of the scalp. We compared across subjects 1) the predicted magnitude production for a standard pressure pulse and 2) the slope (beta) and 3) the intercept (INT) of the Stevens power law to the summed GFP over 20-100 ms poststimulus. Both the magnitude production for a standard pressure pulse and the beta showed an inverse relationship with the summed GFP over 20-100 ms poststimulus, although there was no relationship between INT and the summed GFP. This may partially reflect characteristics of the mechanosensors and surely includes aspects of cognitive judgment, because we found and corrected for a high correlation between, respectively, beta (and INT) for pressure pulses and beta (and INT) for estimation of line lengths, a nonrespiratory modality. The relatively shallow, even inverse GFP-to-perception relationship suggests that, despite marked differences in the magnitude of afferent traffic, normal subjects seem to perceive things similarly.
Daubenspeck
J A
JA
Department of Physiology, Dartmouth Medical School, Dartmouth College, Hanover, New Hampshire 03756, USA. andrew.daubenspeck@darmouth.edu
Manning
H L
HL
Baird
J C
JC
D000465:Algorithms; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D006801:Humans; D008465:Mechanoreceptors / Q000502:physiology; D009055:Mouth / Q000294:innervation / Q000502:physiology*; D010465:Perception / Q000502:physiology*; D011312:Pressure