title: Unchanged incidence of lower-limb amputations in a German City, 1990-1998.
abstract: OBJECTIVE
  A reduction of diabetes-related amputations by at least one-half within 5 years was declared a primary objective for Europe (St. Vincent Declaration, 1989). We collected data about incidence rates of amputations in one German city (Leverkusen, with a population of approximately 160,000 inhabitants) between 1990 and 1998 to ascertain a potential change in rates of incidence.
  
  
  METHODS
  From all three hospitals in Leverkusen, we obtained complete lists of lower-limb amputations. From each patient record, diabetic status was determined. Only the first observed amputation was counted for the analysis. We estimated incidence rates of amputations in the entire population, the diabetic population, and the nondiabetic population. To test for time trend, we fitted Poisson regression models, adjusting for age and sex.
  
  
  RESULTS
  During, the defined period (the years 1990, 1991, and 1994-1998), 339 patients (all residents of Leverkusen) without previous amputations had nontraumatic lower-limb amputations. Of all subjects. 46% were female. Moreover, 76% of the subjects were known to have diabetes. Mean age was 71.3 years. Incidence rates in the diabetic population (standardized to the estimated German diabetic population, per 100,000 person-years) were as follows: 1990, 549; 1991, 356; 1994, 544; 1995, 386; 1996, 426; 1997, 433; and 1998, 463. The Poisson models showed no significant change of incident amputations over time in the diabetic population or in the nondiabetic population.
  
  
  CONCLUSIONS
  Beyond random variation, no change of incidence rates could be observed over the past 9 years. More specific interventions are needed to achieve a substantial reduction of diabetes-related amputations.
authors.affiliation: University of Bielefeld, School of Public Health, Germany. christoph.trautner@uni-bielefeld.de
authors.forename: C
authors.initials: C
authors.lastname: Trautner
authors.forename: B
authors.initials: B
authors.lastname: Haastert
authors.forename: M
authors.initials: M
authors.lastname: Spraul
authors.forename: G
authors.initials: G
authors.lastname: Giani
authors.forename: M
authors.initials: M
authors.lastname: Berger
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical / Q000706:statistics & numerical data*; D002648:Child; D002675:Child, Preschool; D017719:Diabetic Foot / Q000453:epidemiology* / Q000601:surgery*; D005260:Female; D005858:Germany; D006801:Humans; D007223:Infant; D007866:Leg; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D016012:Poisson Distribution; D012044:Regression Analysis; D013997:Time Factors; D014505:Urban Population / Q000706:statistics & numerical data