Cellular signalling: stressing the importance of PIP3.
The lipid second messenger PIP3 was previously thought to be generated exclusively by type I PI 3-kinases. Now, a novel route of PIP3 synthesis, controlled by an unrelated enzyme family, has been discovered, increasing our understanding of the versatility of PIP3 in cellular signalling.
Hinchliffe
K A
KA
University of Cambridge, Department of Pharmacology, Tennis Court Road, CB2 1QJ, Cambridge, UK. kh224@cam.ac.uk
D018129:Phosphatidylinositol Phosphates / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*
D018129:Phosphatidylinositol Phosphates