Chemokines in host-protozoan-parasite interactions.
Here, we review the interactions between parasites and chemokines and chemokine receptors in toxoplasmosis, trypanosomiasis, leishmaniasis, malaria and other diseases caused by protozoan parasites. The potential roles of chemokines after infection by these intracellular pathogens include host defence functions such as leukocyte recruitment, participation in cell-mediated immunity and antiprotozoal activity. However, these interactions can also help the parasite in, for example, the penetration of host cells.
Brenier-Pinchart
M P
MP
Interactions Cellulaires Parasite-Hôte, CNRS-ER2014, Faculté de Médecine, Université J. Fourier, Domaine de la Merci, 38706 La Tronche, France.
Pelloux
H
H
Derouich-Guergour
D
D
Ambroise-Thomas
P
P
D000562:Amebiasis / Q000276:immunology / Q000503:physiopathology; D000818:Animals; D018925:Chemokines / Q000502:physiology*; D003457:Cryptosporidiosis / Q000276:immunology / Q000503:physiopathology; D056890:Eukaryota / Q000502:physiology*; D006790:Host-Parasite Interactions; D007111:Immunity, Cellular; D007896:Leishmaniasis / Q000276:immunology / Q000503:physiopathology; D008288:Malaria / Q000276:immunology / Q000503:physiopathology; D014123:Toxoplasmosis / Q000276:immunology / Q000503:physiopathology; D014245:Trichomonas Infections / Q000276:immunology / Q000503:physiopathology; D014352:Trypanosomiasis / Q000276:immunology / Q000503:physiopathology
D018925:Chemokines