Chromosome condensation: packaging the genome.
The packaging of centimetre long DNA molecules into compact metaphase chromosomes is essential for genome segregation in anaphase. The chromosomal condensin complex plays a crucial part in this packaging, and important new insight into condensin action in vitro and in vivo has recently been gained.
Uhlmann
F
F
Chromosome Segregation Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, WC2A 3PX, London, UK. f.uhlmann@icrf.icnet.uk
D000251:Adenosine Triphosphatases / Q000502:physiology; D000818:Animals; D002875:Chromosomes; D004268:DNA-Binding Proteins / Q000235:genetics; D016678:Genome
D004268:DNA-Binding Proteins; D000251:Adenosine Triphosphatases