In vitro growth of Leishmania amazonensis promastigotes resistant to pentamidine is dependent on interactions among strains.
The in vitro growth of promastigote cells of Leishmania amazonensis was found to strongly depend on interactions among strains that differed in their pentamidine resistance. In particular, the growth of resistant strains was reduced when they shared the same environment with a less-resistant strain.
Agnew
P
P
Centre d'Etudes sur le Polymorphisme des Microorganismes (CNRS/IRD UMR 9926), IRD, 34032 Montpellier Cedex 01, France. agnew@cepm.mpl.ird.fr
Holzmuller
P
P
Michalakis
Y
Y
Sereno
D
D
Lemesre
J L
JL
Renaud
F
F
D000818:Animals; D000981:Antiprotozoal Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D007891:Leishmania / Q000187:drug effects* / Q000254:growth & development; D010419:Pentamidine / Q000494:pharmacology*; D013045:Species Specificity
D000981:Antiprotozoal Agents; D010419:Pentamidine