Cytohistological correlation of abnormal cervical lesions in Native American females in Mississippi.
Earlier studies have reported that cervical cancer mortality and incidence rates in Native American women are one of the highest in the United States. In recent years, the rate of abnormal cervical lesions in this group has been a public health concern. The objective of this study was to evaluate a cytohistologic correlation of abnormal cervical lesions in Native American women in Mississippi. The cytohistologic results from 77 Native American women with an abnormal diagnosis were reported to the University of Mississippi Medical Center during 1993-1996. The cases were divided into four groups; which included 7(9%) atypical squamous cells of undetermined significance (ASCUS), 51(66%) low-grade squamous intraepithelial lesions (LGSIL), 19(25%) high-grade squamous intraepithelial lesions (HGSIL), and no invasive carcinomas. Out of the study cases, 57 women presented with an abnormal gynecological history. The mean age was 29.97 years with a range of 14 to 87. The results were tallied and evaluated using SPSS. Only, 57 cases had a histologic evaluation, with an overall correlation rate of 84% (48/57). The histopathologic diagnosis confirmed 12 negative, 26 CIN I, 17 CIN II/CIN III, and 2 invasive carcinomas. The results of this study conclude that cervical intraepithelial lesions are significant among Native American women in Mississippi. Fifty-six (98%) of the patients with histologic evaluations presented with an abnormal gynecologic history; therefore, education and routine cytologic screening is imperative for the detection of cervical cancer in high-risk groups.
Alexander
C
C
Department of Cytotechnology, School of Health Related Professions, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Cason
Z
Z
Benghuzzi
H
H
Martin
L
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007198:Indians, North American; D008875:Middle Aged; D008922:Mississippi / Q000453:epidemiology; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000208:ethnology*; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis / Q000208:ethnology*