Hortein, a new natural product from the fungus Hortaea werneckii associated with the sponge Aplysina aerophoba.
The fungus Hortaea werneckii isolated from the Mediterranean sponge Aplysina aerophoba, collected at Banyuls-sur-Mer in southern France, yielded a new compound named hortein (1), which possesses a unique ring system hitherto unknown for natural products. The structure of 1 was established on the basis of 1D and 2D NMR spectroscopic and mass spectrometric (ESI, CI, FAB, EI) data.
Brauers
G
G
Heinrich-Heine-Universität, Institut für Pharmazeutische Biologie, Universitätsstrasse 1, Geb. 26.23, D-40255 Düsseldorf, Germany.
Ebel
R
R
Edrada
R
R
Wray
V
V
Berg
A
A
Gräfe
U
U
Proksch
P
P
D000818:Animals; D001419:Bacteria / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D007306:Insecticides / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008522:Mediterranean Sea; D008826:Microbial Sensitivity Tests; D011084:Polycyclic Aromatic Hydrocarbons / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D011161:Porifera / Q000382:microbiology*; D021241:Spectrometry, Mass, Electrospray Ionization; D016339:Spectrometry, Mass, Fast Atom Bombardment
D007306:Insecticides; D011084:Polycyclic Aromatic Hydrocarbons; C433955:hortein