title: Relation between headache in childhood and physical and psychiatric symptoms in adulthood: national birth cohort study.
abstract: OBJECTIVE
  To elucidate the associations between frequent headache and psychosocial factors in childhood and to determine whether such children are at an increased risk of headache, multiple physical symptoms, and psychiatric symptoms in adulthood.
  
  
  METHODS
  Population based birth cohort study.
  
  
  METHODS
  General population.
  
  
  METHODS
  People participating in the national child development study, a population based birth cohort study established in 1958.
  
  
  METHODS
  Headache, multiple physical symptoms, and psychiatric morbidity at age 33.
  
  
  RESULTS
  Headache in childhood was associated with several psychosocial factors. Prospectively, children with frequent headache had an increased risk in adulthood of headache (odds ratio 2.22, 95% confidence interval 1.62 to 3.06), multiple physical symptoms (1.75, 1.46 to 2.10), and psychiatric morbidity (1.41, 1.20 to 1.66). The outcomes of headache and multiple physical symptoms were not accounted for by psychiatric morbidity.
  
  
  CONCLUSIONS
  Children with headache are at an increased risk of recurring headache in adulthood and may complain of other physical and psychiatric symptoms. Strategies for coping with psychosocial adversity in childhood may improve the prognosis in adulthood.
authors.affiliation: Institute of Psychiatry and Guy's, King's and St Thomas's School of Medicine, De Crespigny Park, London SE5 8AF. p.fearon@iop.kcl.ac.uk
authors.forename: P
authors.initials: P
authors.lastname: Fearon
authors.forename: M
authors.initials: M
authors.lastname: Hotopf
mesh_terms: D000328:Adult; D002648:Child; D015331:Cohort Studies; D006261:Headache / Q000453:epidemiology / Q000523:psychology*; D006801:Humans; D007231:Infant, Newborn; D001523:Mental Disorders / Q000209:etiology*; D015995:Prevalence; D011379:Prognosis; D011446:Prospective Studies; D012008:Recurrence; D012307:Risk Factors; D012923:Social Class; D006113:United Kingdom / Q000453:epidemiology