title: New onset diabetes mellitus in an HIV-positive adolescent.
abstract: The authors report an 18-year-old girl with HIV infection who developed new-onset insulin-dependent diabetes mellitus (IDDM) in association with anemia. IDDM among patients with HIV infection has been infrequently reported and suggested to be caused by different etiologies. Susceptibility to autoimmune diseases, such as IDDM, has been associated functionally with two members of a newly described multigene family called PERB11. In this patient, the progression of hyperglycemia associated with a rapid increase in insulin requirement is suggestive of insulin resistance.
authors.affiliation: Department of Pediatrics, SUNY Health Science Center at Brooklyn, USA.
authors.forename: I
authors.initials: I
authors.lastname: Abdel-Khalek
authors.forename: H J
authors.initials: HJ
authors.lastname: Moallem
authors.forename: S
authors.initials: S
authors.lastname: Fikrig
authors.forename: S
authors.initials: S
authors.lastname: Castells
mesh_terms: D000293:Adolescent; D000740:Anemia / Q000150:complications* / Q000628:therapy; D001786:Blood Glucose / Q000032:analysis; D001803:Blood Transfusion; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000150:complications* / Q000276:immunology; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D007333:Insulin Resistance / Q000276:immunology
chemical_list: D001786:Blood Glucose; D007328:Insulin