Towards a novel treatment strategy for acute pancreatitis. 2. Principles and potential practice.
In part 1 it was argued that a 'free radical-mast cell' template for the aetiogenesis of acute pancreatitis accommodates the evidence, whereas the prevailing 'trypsin-cytokine' template does not. In this sequel I examine the ramifications of the new philosophy in relation to speedier diagnosis, prognostic aids and, above all, a programme of active treatment which - once validated in experimental studies - could be implemented by the first medical respondent.
Braganza
J M
JM
Pancreato-Biliary Service, Manchester Royal Infirmary, Manchester, UK. jenny.parr@man.ac.uk
D000208:Acute Disease; D003131:Combined Modality Therapy; D018450:Disease Progression; D004638:Emergency Treatment / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D010195:Pancreatitis / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D011379:Prognosis; D012720:Severity of Illness Index; D015996:Survival Rate; D013997:Time Factors