title: Contraversive eye deviation during deep brain stimulation of the globus pallidus internus.
abstract: Clinical signs help determine correct electrode positioning during stereotactic implantation for chronic high-frequency pallidal stimulation in Parkinson's diease (PD). The authors describe a patient who had marked, sustained, contraversive eye deviation caused by stimulation during pallidal surgery. The underlying mechanism is probably an excitation of fibers in the internal capsule by volume-conducted current spread. Such conjugate eye deviation is thus not necessarily an indication of incorrect electrode placement.
authors.affiliation: Department of Neurology, Ludwig-Maximilians University, Munich, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Anagnostou
authors.forename: B
authors.initials: B
authors.lastname: Sporer
authors.forename: U
authors.initials: U
authors.lastname: Steude
authors.forename: U
authors.initials: U
authors.lastname: Kempermann
authors.forename: U
authors.initials: U
authors.lastname: Büttner
authors.forename: K
authors.initials: K
authors.lastname: Bötzel
mesh_terms: D004599:Electric Stimulation Therapy; D004567:Electrodes, Implanted; D005133:Eye Movements / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D005917:Globus Pallidus / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D020772:Internal Capsule / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D007431:Intraoperative Complications / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D015835:Ocular Motility Disorders / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D010300:Parkinson Disease / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome