title: [Studies on the chemical constituents of Kaempferia marginata].
abstract: OBJECTIVE
  To study the chemical constituents of the rhizomes of Kaempferia galanga L. (Zingiberaceae).
  
  
  METHODS
  Various chromatographic techniques were used to separate and purify. Their physico-chemical properties and spectral data were used to elucidate the structures.
  
  
  RESULTS
  Six compounds were isolated from the hexane extract of K. galanga. Their structures were identified as marginatol (1), 8 (14), 15-sanderacopimaradiene-1 alpha, 9 alpha-diol (2), 8 (14), 15-sanderacopimaradiene-1 alpha, 6 beta, 9 alpha-triol (3), germacrone (4), trans-ethyl p-methoxycinnamate (5) and n-pentadecane (6) on the basis of spectral data (IR, MS, 1H-1H, 13C-1H NMR, NOEs and HMBC).
  
  
  CONCLUSIONS
  Marginatol (1) is a new isopimarene diterpenoid and was elucidated as 8(14), 15-isopimaradiene-6 alpha-ol. Compounds 2, 3 and 4 were isolated for the first time from this plant.
authors.affiliation: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Bejing 100094, China.
authors.forename: J G
authors.initials: JG
authors.lastname: Yu
authors.forename: D L
authors.initials: DL
authors.lastname: Yu
authors.forename: S
authors.initials: S
authors.lastname: Zhang
authors.forename: X Z
authors.initials: XZ
authors.lastname: Luo
authors.forename: L
authors.initials: L
authors.lastname: Sun
authors.forename: C C
authors.initials: CC
authors.lastname: Zheng
authors.forename: Y H
authors.initials: YH
authors.lastname: Chen
mesh_terms: D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D018517:Plant Roots / Q000737:chemistry*; D030521:Zingiberaceae / Q000737:chemistry*
chemical_list: D004224:Diterpenes