Interaction of immunophilin-binding immunosuppressives with the glucocorticoid receptor signaling pathway: implications for transplantation.
Brogan
I J
IJ
Transplant Immunology Research Group, School of Biological Sciences, University of Manchester, Manchester, UK. ibrogan@fs1.scg.man.ac.uk
Geraghty
P J
PJ
Hutchinson
I V
IV
D000818:Animals; D006085:Graft Survival / Q000187:drug effects / Q000276:immunology*; D006801:Humans; D020104:Immunophilins / Q000378:metabolism*; D007166:Immunosuppressive Agents / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000276:immunology; D016031:Liver Transplantation / Q000276:immunology; D008954:Models, Biological; D011965:Receptors, Glucocorticoid / Q000187:drug effects / Q000502:physiology*; D015398:Signal Transduction / Q000187:drug effects / Q000502:physiology*; D015533:Transcriptional Activation; D014181:Transplantation Immunology
D007166:Immunosuppressive Agents; D011965:Receptors, Glucocorticoid; D020104:Immunophilins