Secondary chronic myelogenous leukemia after autologous peripheral blood stem cell transplantation for lymphoma.
A 31-year-old woman was diagnosed with intestinal lymphoma (high-grade mucosa-associated lymphoid tissue lymphoma, stage IIE) in September 1996. Eleven courses of chemotherapy were administered, but the results were poor. She received autologous peripheral blood stem cell transplantation (PBSCT) in September 1997. Leukocytosis was noted, and chronic myelogenous leukemia was diagnosed 8 months after the PBSCT, progressing to blast phase 10 months later. We report this case because secondary chronic myelogenous leukemia after stem cell transplantation is rare.
Hsiao
H H
HH
Department of Internal Medicine, Kaohsiung Medical University Hospital, Taiwan.
Liu
T C
TC
Chang
C S
CS
Sue
Y C
YC
Chen
T P
TP
Lin
S F
SF
D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D007414:Intestinal Neoplasms / Q000473:pathology / Q000628:therapy; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D018442:Lymphoma, B-Cell, Marginal Zone / Q000473:pathology / Q000628:therapy*; D016609:Neoplasms, Second Primary / Q000209:etiology* / Q000473:pathology; D014182:Transplantation, Autologous / Q000009:adverse effects
D000970:Antineoplastic Agents