title: Sigmoid cystoplasty with argon beam without mucosa.
abstract: OBJECTIVE
  Intestinal bladder augmentations have well recognized complications, including mucus production, metabolic abnormalities and perforation. These complications may be avoided if the intestinal mucosa is not incorporated in the urinary tract. We report our experience with sigmoid cystoplasty without mucosa using argon beam, and describe the clinical, urodynamic, ultrasound and pathological results.
  
  
  METHODS
  We performed sigmoid cystoplasty without mucosa in 26 patients and with argon beam over the mucosa before it was removed in 6 boys and 4 girls with a mean age of 8 years (range 3 to 14). All patients had neurogenic bladder as the initial disease. Indications for augmentation were poor bladder compliance, low bladder capacity, hydronephrosis and urinary incontinence. Mean followup was 18 months (range 8 to 40) and included ultrasound, urodynamic evaluation, renal function and clinical assessment. In all patients intraoperative biopsies were done. In 8 of the 10 patients endoscopic biopsies of the augmented segment were obtained between 6 months and 2 years postoperatively. The operation consisted of the Goodwin technique without mucosa, which was treated with argon beam before it was removed.
  
  
  RESULTS
  The 10 patients are dry on intermittent clean catheterization with intervals of greater than 4 hours. There have been no clinical urinary tract infections. Two patients presented with peristaltic contractions and no symptoms. Bladder capacity increased from 80 (range 45 to 200) to 300 (220 to 400) ml., and mean postoperative compliance was 15 ml./cm. H2O (range 9 to 38). There were no significant changes in the urodynamic data between patients treated with sigmoid cystoplasty without mucosa only and with argon beam. Intraoperative biopsies after treatment with argon beam showed damaged mucosa and muscularis mucosa, and intact serosa, muscularis and submucosa layers. On the 8 argon beam postoperative biopsies the sigmoid submucosa was covered with a pseudostratified metaplasia of connective tissue with collagen fibers without scars (trichromic technique).
  
  
  CONCLUSIONS
  Sigmoid cystoplasty without mucosa with argon beam is easy to perform. The clinical and urodynamic results have been satisfactory, and use of argon beam prevents postoperative bleeding and residual glands.
authors.affiliation: Department of Pathology, Pediatric Urology Service, Hospital Italiano, Buenos Aires, Argentina.
authors.forename: F
authors.initials: F
authors.lastname: De Badiola
authors.forename: E
authors.initials: E
authors.lastname: Ruiz
authors.forename: J
authors.initials: J
authors.lastname: Puigdevall
authors.forename: P
authors.initials: P
authors.lastname: Lobos
authors.forename: J
authors.initials: J
authors.lastname: Moldes
authors.forename: M
authors.initials: M
authors.lastname: Lopez Raffo
authors.forename: A
authors.initials: A
authors.lastname: Gallo
mesh_terms: D000293:Adolescent; D001128:Argon; D002648:Child; D002675:Child, Preschool; D012809:Colon, Sigmoid / Q000637:transplantation*; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa; D053685:Laser Therapy; D008297:Male; D019651:Plastic Surgery Procedures; D001743:Urinary Bladder / Q000601:surgery*; D014563:Urodynamics; D013520:Urologic Surgical Procedures
chemical_list: D001128:Argon