Long-term prognosis of acute aortic dissection with medical treatment: a survey of 263 unoperated patients.
Between 1973 and 1998, 263 patients with acute aortic dissection were medically treated only. They were divided into 4 groups: Stanford type A and B with open false lumen (open) or with early thrombosed false lumen (thrombosed). An event was defined as death by dissection or re-dissection. Gender, age, maximum diameter of dissected aorta and presence of shock at onset were examined as risk factors. In the open false lumen group, the presence of shock was associated with the event. During the chronic period, the diameter of the aorta was associated with prognosis in open type B dissection. The rate of event was higher in the open type A and B groups than in the thrombosed type A and B groups; however, there was no difference in the event-free rate between types A and B in patients surviving the acute period. The prognosis of medically treated dissecting aorta was not poor in patients with type B or with early thrombosed false lumen. The presence of shock at onset with open false lumen and the diameter of the aorta (> or =40 mm) in type B were significantly correlated with a poor prognosis.
Kozai
Y
Y
The Third Department of Internal Medicine, Chiba University School of Medicine, Japan.
Watanabe
S
S
Yonezawa
M
M
Itani
Y
Y
Inoue
T
T
Takasu
J
J
Masuda
Y
Y
D000368:Aged; D000784:Aortic Dissection / Q000188:drug therapy / Q000401:mortality* / Q000601:surgery; D001014:Aortic Aneurysm / Q000188:drug therapy / Q000401:mortality* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D016019:Survival Analysis