Successful thalidomide treatment of severe infantile Behçet disease.
We describe an 11-month-old child with giant ulcers of the buccal mucosa, necrosis of the tongue, abdominal tenderness, and severe diarrhea due to Behçet disease. Treatment with thalidomide resulted in prompt recovery of the mucocutaneous lesions and gastrointestinal manifestations.
Brik
R
R
Department of Pediatrics, Rambam Medical Center and B. Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. r_brik@rambam.health.gov.il
Shamali
H
H
Bergman
R
R
D001528:Behcet Syndrome / Q000188:drug therapy* / Q000473:pathology; D003879:Dermatologic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007223:Infant; D012867:Skin / Q000187:drug effects / Q000473:pathology; D013792:Thalidomide / Q000627:therapeutic use*; D016896:Treatment Outcome
D003879:Dermatologic Agents; D013792:Thalidomide