Asymptomatic hypercalciuria: prevalence and metabolic characteristics.
Hypercalciuria is of continuing interest as a risk factor for kidney stones in children. We screened 592 healthy Turkish children (308 boys, 284 girls, aged 3 month-16 years) for hypercalciuria by measurement of urinary calcium/creatinine (UCa/Cr) ratio in the second-morning urine samples. Hypercalciuria was noted in 17 children (2.9%), 9 of them were boy and 8 of them were girl. Oral calcium-loading test could only be done in 7 children who were diagnosed as having hypercalciuria, and it revealed absorptive hypercalciuria in 2 cases and renal hypercalciuria in no cases. The frequency of a family history of urolithiasis in asymptomatic hypercalciuric children was 50%. Median UCa/Cr ratios and urinary magnesium/creatinine (UMg/Cr) ratios were 0.11 and 0.10 and the 97th percentiles were 0.32 and 0.23 respectively. The UCa/Cr ratio in second-morning urine samples was correlated with the UMg/Cr ratio (r = 0.44) and was independent of age and sex.
Berçem
G
G
Department of Pediatrics, Cumhuriyet University Faculty of Medicine, Sivas.
Cevit
O
O
Toksoy
H B
HB
Içagasioglu
D
D
Gültekin
A
A
Tanzer
F
F
D000293:Adolescent; D002118:Calcium / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000652:urine; D005260:Female; D006801:Humans; D007223:Infant; D008274:Magnesium / Q000652:urine; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology
D003404:Creatinine; D008274:Magnesium; D002118:Calcium