[Fibrosarcomatous variant of dermatofibrosarcoma protuberans: clinicopathologic analysis of 4 cases].
We present a series of 4 cases of fibrosarcomatous dermatofibrosarcoma protuberans. This variant, which is composed of areas of typical DFSP associated with more cellular, fascicular foci, reminiscent of fibrosarcoma, should be recognised because of its more aggressive behavior, with a significant metastatic potential (15%). Our series illustrates the clinical, morphological, immunohistochemical and cytogenetic features of this uncommon tumor, with emphasis on differential diagnosis.
Diedhiou
A
A
Service d'Anatomie Pathologique, Institut Jules Bordet, 1, rue Héger-Bordet, 1000 Bruxelles, Belgique.
Larsimont
D
D
Vandeweyer
E
E
Andry
G
G
De Saint-Aubain Somerhausen
N
N
D000328:Adult; D018223:Dermatofibrosarcoma / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008875:Middle Aged; D008938:Mitosis; D009362:Neoplasm Metastasis; D011379:Prognosis; D012878:Skin Neoplasms / Q000473:pathology*