Shape of lens epithelial cells after intraocular lens implantation.
OBJECTIVE
To evaluate the morphological behavior of lens epithelial cells (LECs) after human cataract surgery with implantation of a poly(methyl methacrylate) (PMMA) or silicone intraocular lens (IOL).


METHODS
Department of Ophthalmology, Fujita Health University, Banbuntane Hotokukai Hospital, Nagoya, Aichi, Japan.


METHODS
Morphological observations of LECs in the patients with IOLs were made by light and transmission electron microscopy. The LECs were from 4 areas: (1) the region below the anterior capsule, touching the IOL; (2) the area between region 1 and the equatorial region; (3) the equatorial region; and (4) the central equatorial region and of the posterior capsule not touching the IOL. Case 1 had implantation of a single-piece IOL with a PMMA optic and haptics. Case 2 had a 3-piece IOL with a PMMA optic and polypropylene haptics. Case 3 had a 3-piece IOL with a silicone optic and polypropylene haptics. Areas 1 and 4 could not be observed in Case 2.


RESULTS
The major difference between the patient with a PMMA IOL (Case 1) and the patient with a silicone IOL (Case 3) was that among the 4 areas observed, collagen fibers were present only in area 1 in Case 1 but in areas 2 or 3 as well in Case 3.


CONCLUSIONS
Fibrous collagen fibers appeared in regions in which LECs adhered and there was capsule contact with the IOL optic. In addition fibrous collagen fibers appeared in more areas in the eye with the silicone IOL than in that with the PMMA IOL, perhaps because IOLs with silicone optics move slightly while in the capsular bag.
Majima
K
K
Department of Ophthalmology, Fujita Health University, Banbuntane Hotokukai Hospital, Nagoya, Japan.
Majima
Y
Y
D000368:Aged; D048429:Cell Size; D020878:Device Removal; D004847:Epithelial Cells / Q000473:pathology* / Q000648:ultrastructure; D005548:Foreign-Body Migration / Q000209:etiology / Q000601:surgery; D006801:Humans; D019654:Lens Implantation, Intraocular; D007908:Lens, Crystalline / Q000473:pathology* / Q000648:ultrastructure; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification / Q000009:adverse effects; D019904:Polymethyl Methacrylate; D011475:Prosthesis Failure; D012826:Silicone Elastomers
D012826:Silicone Elastomers; D019904:Polymethyl Methacrylate