Large animal models for testing bioartificial liver support systems.
After development of a flat membrane bioreactor using primary hepatocytes (FMB) further preclinical investigations were necessary. To study safety and efficiency of liver support systems there is a need for a well-defined large animal model.
Frühauf
N R
NR
Dep. of General and Transplant Surgery, University Essen, Germany.
Kaiser
G M
GM
Nosser
S A
SA
Bader
A
A
Oldhafer
K J
KJ
D000818:Animals; D004195:Disease Models, Animal; D017093:Liver Failure / Q000209:etiology / Q000628:therapy*; D019164:Liver, Artificial