title: Localization of heme oxygenase-2 in the canine larynx.
abstract: The localization of heme oxygenase-2 (HO-2) in the larynx of the dog was investigated using immunohistochemistry. HO-2-positive cells were seen among neurons in intralaryngeal ganglia. Nerve fibers positive to HO-2 immunohistochemistry were seen surrounding laryngeal glands and arterioles and also in the adventitia of arterioles. HO-2-positive fibers were also seen running parallel to the mucosa in the lamina propria but no positive fibers were seen in the epithelium. Some of the intramuscular neurons found in the intrinsic laryngeal muscles were HO-2-positive, although no positive motor fibers were seen, and the neuromuscular junctions were also HO-2-negative. The results implicate the participation of HO-2-in the parasympathetic innervation of the larynx.
authors.affiliation: Department of Otolaryngology, Kyoto Prefectural University of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Koike
authors.forename: T
authors.initials: T
authors.lastname: Uno
authors.forename: H
authors.initials: H
authors.lastname: Bamba
authors.forename: K
authors.initials: K
authors.lastname: Shogaki
authors.forename: R
authors.initials: R
authors.lastname: Hirota
authors.forename: Y
authors.initials: Y
authors.lastname: Hisa
mesh_terms: D000818:Animals; D004285:Dogs; D005260:Female; D006419:Heme Oxygenase (Decyclizing) / Q000032:analysis*; D007124:Immunoenzyme Techniques; D007823:Laryngeal Nerves / Q000473:pathology*; D007830:Larynx / Q000473:pathology*; D008297:Male; D009412:Nerve Fibers / Q000473:pathology; D009474:Neurons / Q000473:pathology; D012016:Reference Values; D009435:Synaptic Transmission / Q000502:physiology
chemical_list: D006419:Heme Oxygenase (Decyclizing); C105245:heme oxygenase-2