Ras effectors: buying shares in Ras plc.
The debate over whether activated Ras can regulate phosphoinositide-specific phospholipase C (PLC) has been contentious and at times heated. The argument may be resolved by the recent identification of a novel Ras-regulated PLC, but some unexpected properties of this protein are sure to stimulate further controversy.
Cullen
P J
PJ
Department of Biochemistry, University of Bristol, BS8 1TD, Bristol, UK. Pete.Cullen@bris.ac.uk
D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D043265:Phosphatidylinositol Diacylglycerol-Lyase; D010738:Type C Phospholipases / Q000378:metabolism*; D018631:ras Proteins / Q000378:metabolism*
D007527:Isoenzymes; D010738:Type C Phospholipases; D018631:ras Proteins; D043265:Phosphatidylinositol Diacylglycerol-Lyase