title: Use of hair pores to determine the orientation of collagen fibers in skin.
abstract: Most people are interested in recovery of skin defects caused by burn, scald or trauma from the aesthetic and functional point of view. It will occupy an important role for successful skin graft for patients with such skin defects that the orientation of collagen fibers in the grafted skin matches to the fiber orientation in surrounding skin. There have been, to my best knowledge, no methods for determining the orientation of collagen fibers in the skin from the clinical point of view. Recently, the author has found a new method for directly determining the collagen-fiber orientation without cutting samples from a calf leather by analyzing the anisotropic shape of hair pore. Its principle is based on the quantitative evaluation of collagen-fiber orientation by approximating a hair pore to an ellipse. The results obtained by the new method using hair pores were supported by the microwave method, mechanical measurements and scanning electron microscopy. Such a method will be applicable for determining the orientational distribution of collagen fibers in skins of animals and humans and give a valuable probe for performing skin grafting based on the scientific data of hair pores.
authors.affiliation: Department of Chemistry, Faculty of Medicine, Nara Medical University, Kashihara, Nara 634-8521, Japan. s-osaki@naramed-u.ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Osaki
mesh_terms: D000818:Animals; D016880:Anisotropy; D002417:Cattle; D003094:Collagen / Q000648:ultrastructure*; D018859:Hair Follicle / Q000648:ultrastructure*; D008855:Microscopy, Electron, Scanning; D008872:Microwaves; D012867:Skin / Q000648:ultrastructure*; D016038:Skin Transplantation / Q000379:methods*
chemical_list: D003094:Collagen