title: Correlation between coagulation profile findings and bleeding complications after ultrasound-guided biopsies: 434 cases (1993-1996).
abstract: Medical records of 434 consecutive dogs (n=310) and cats (n=124) that received coagulation studies prior to ultrasound-guided biopsy procedures between January 1993 and June 1996 were reviewed for bleeding complications. Minor complications occurred in 21.9% of cases. Major complications occurred in 6% of the cases. Significant bleeding complications were observed in thrombocytopenic cases (P=0.0001). Dogs with a prolonged one-stage prothrombin time (OSPT) (P=0.031) and cats with prolonged activated partial thromboplastin time (aPTT) (P=0.024) were more likely to have complications than patients with normal values. Adequate tissue for histopathological diagnosis was obtained in 96.3% of cases. The likelihood of complication was smaller when the liver was biopsied than when the kidney was biopsied (n=259; P=0.0327). Ultrasound-guided biopsy of intracavitary structures is an effective and relatively safe procedure, but delay of the procedure should be considered when thrombocytopenia is present in the patient.
authors.affiliation: Department of Clinical Sciences, School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts 01536, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Bigge
authors.forename: D J
authors.initials: DJ
authors.lastname: Brown
authors.forename: D G
authors.initials: DG
authors.lastname: Penninck
mesh_terms: D000818:Animals; D001706:Biopsy / Q000009:adverse effects / Q000662:veterinary*; D001780:Blood Coagulation Tests / Q000662:veterinary*; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D007680:Kidney Neoplasms / Q000473:pathology / Q000662:veterinary*; D008113:Liver Neoplasms / Q000473:pathology / Q000662:veterinary*; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000662:veterinary*; D011996:Records / Q000662:veterinary; D012189:Retrospective Studies; D018084:Ultrasonography, Interventional / Q000009:adverse effects / Q000662:veterinary*