title: [Chemical obliterans bronchiolitis after azotic acid exposure].
abstract: The authors present the case of a 48 years old man having an exposure to irritant gases (azotic and lactic acids) in a closed space, inhaling them for 5 minutes. Shortly after the accident the patient displayed the signs of corneal and conjunctival burn; several days afterwards respiratory symptoms appeared: shortness of breath, dyspnea to minor efforts, then nocturnal dyspnea and orthopnea. Chest X-ray, CT scan, complex lung function tests and bronchoalveolar lavaje, together with the history of recent exposure to irritant gases led to the diagnosis of hypersensitivity obliterant bronchiolitis. Oral corticoids in dose of 60 mg/day determined a substantial clinical, radiological and functional improvement. The authors make some comments on the need of early diagnosis and efficient treatment.
authors.affiliation: Institutul Naţional de Pneumologie Marius Nasta Bucureşti.
authors.forename: F
authors.initials: F
authors.lastname: Mihălţan
authors.forename: C
authors.initials: C
authors.lastname: Marcu
authors.forename: T
authors.initials: T
authors.lastname: Ciprut
authors.forename: R
authors.initials: R
authors.lastname: Nemeş
authors.forename: A
authors.initials: A
authors.lastname: Serbescu
authors.forename: E
authors.initials: E
authors.lastname: Halic
authors.forename: D
authors.initials: D
authors.lastname: Ungureanu
authors.forename: C
authors.initials: C
authors.lastname: Badea
authors.forename: L
authors.initials: L
authors.lastname: Davidescu
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001989:Bronchiolitis Obliterans / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D005739:Gas Poisoning / Q000150:complications*; D006801:Humans; D019344:Lactic Acid / Q000506:poisoning; D008297:Male; D008875:Middle Aged; D009584:Nitrogen / Q000506:poisoning; D016273:Occupational Exposure / Q000009:adverse effects*; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D019344:Lactic Acid; D009584:Nitrogen; D011241:Prednisone