title: Efficacy of 1.25% amitraz solution in the treatment of generalized demodicosis (eight cases) and sarcoptic mange (five cases) in dogs.
abstract: Eight dogs with generalized demodicosis and five with sarcoptic manage were treated with 1.25% amitraz solution applied weekly and associated with an antidote treatment (atipamezol, 0.1 mg kg-1 i.m. once: and yohimbine 0.1 mg kg-1 once daily for 3 days, orally). Results of skin scrapings were used to determine whether therapy should be continued or stopped. The median number of treatments for demodicosis and sarcoptic mange was three (range 2-5) and two (range 1-3), respectively. Some side-effects were observed but all were stopped with antidote treatment; no failure or relapses occurred at 6-36 months after treatment.
authors.affiliation: Clinique vétérinaire des Lavandes, 26160 La Bégude de Mazenc, France.
authors.forename: C
authors.initials: C
authors.lastname: Hugnet
authors.forename: C
authors.initials: C
authors.lastname: Bruchon-Hugnet
authors.forename: H
authors.initials: H
authors.lastname: Royer
authors.forename: G
authors.initials: G
authors.lastname: Bourdoiseau
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000627:therapeutic use*; D000317:Adrenergic alpha-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D000818:Animals; D000977:Antiparasitic Agents; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D005260:Female; D007093:Imidazoles / Q000008:administration & dosage / Q000627:therapeutic use; D007273:Injections, Intramuscular / Q000662:veterinary; D007306:Insecticides / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D012532:Scabies / Q000188:drug therapy / Q000662:veterinary; D012876:Skin Diseases, Parasitic / Q000662:veterinary*; D014052:Toluidines / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome; D015016:Yohimbine / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000316:Adrenergic alpha-Agonists; D000317:Adrenergic alpha-Antagonists; D000977:Antiparasitic Agents; D007093:Imidazoles; D007306:Insecticides; D014052:Toluidines; C050701:atipamezole; D015016:Yohimbine; C014983:amitraz