title: Amplitude coded-colour Doppler sonography in paediatric renal disease.
abstract: The aim of our study was to assess the ability of amplitude coded-colour Doppler sonography (ACDS) to depict altered perfusion in paediatric renal disease in a prospective study. Colour Doppler sonography (CDS) and ACDS examinations were performed in 180 renal units (90 patients; age range newborn to 16 years) with unilateral or bilateral renal disease (e.g. reflux nephropathy, renal scars, end-stage renal disease, ureteropelvic junction obstruction, urinary tract infection, renal failure, haemolytic uraemic syndrome, nephrotic syndrome, systemic lupus erythematosus (LE), renal biopsy, congenital dysplasia, tumour/infiltration). The ACDS results were compared with scintigraphy or CT as well as to clinical findings. Amplitude colour-coded Doppler sonography accurately demonstrated normal vasculature in 49 of 51 healthy kidneys (= 96%); 3 healthy kidneys could not be evaluated due to motion/artefacts. In 39 of 43 kidneys with focally altered perfusion ACDS could be performed and correctly depicted focally impaired vasculature/perfusion in 35 kidneys (= 89.7%). Seventy-three of 83 kidneys with diffusely impaired perfusion could be evaluated by ACDS and altered pattern was correctly depicted in 58 kidneys (= 79.4%), with an overall percentage of agreement of 87.1%. Amplitude CDS appears to be useful in infants and children. Compared with CDS it improves visualisation of especially focally impaired vasculature/perfusion and should be considered a valuable adjunct to conventional investigations.
authors.affiliation: Department of Radiology, Division of Paediatric Radiology, University Hospital LKH Graz, Auenbruggenplatz, 8036 Graz, Austria. michael.riccabona@kfunigraz.ac.at
authors.forename: M
authors.initials: M
authors.lastname: Riccabona
authors.forename: E
authors.initials: E
authors.lastname: Ring
authors.forename: W
authors.initials: W
authors.lastname: Schwinger
authors.forename: R
authors.initials: R
authors.lastname: Aigner
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007674:Kidney Diseases / Q000000981:diagnostic imaging*; D008297:Male; D011446:Prospective Studies; D018615:Ultrasonography, Doppler, Color / Q000379:methods