title: Intra-arterial thrombolysis for acute ischemic stroke.
abstract: Intra-arterial thrombolysis is a maturing treatment for acute thromboembolic stroke that shows promise in restoring cerebral blood supply. Reviewed evidence suggests that intra-arterial treatment has a longer window for treatment than intravenous t-PA and does improve outcome. A favorable outcome is dependent on careful patient selection aimed at avoiding intracranial hemorrhage. This article describes features to evaluate for patient selection and highlights factors along the treatment algorithm to maximize success.
authors.affiliation: Department of Diagnostic Radiology, Oregon Health Sciences University, Portland, Oregon 97201-3098, USA.
authors.forename: W C
authors.initials: WC
authors.lastname: Burnette
authors.forename: G M
authors.initials: GM
authors.lastname: Nesbit
mesh_terms: D000208:Acute Disease; D002533:Cerebral Angiography; D007261:Infusions, Intra-Arterial; D008279:Magnetic Resonance Imaging; D020521:Stroke / Q000188:drug therapy*; D015912:Thrombolytic Therapy / Q000379:methods*; D014057:Tomography, X-Ray Computed