[Kojic acid and its derivatives as potential therapeutic agents].
The review paper studies kojic acid, a secondary metabolite of fibrous fungi, as a carrier chemical structure of potential pharmaceuticals. The examined preparative procedures, physico-chemical and biologic properties, and especially the antifungal and antileukemic effects of the parent kojic acid indicate that novel potential drugs can be developed on its basis.
Uher
M
M
Katedra organickej chémie Chemickotechnologickej fakulty Slovenskej technickej univerzity, Bratislava.
Chalabala
M
M
Cizmárik
J
J
D000818:Animals; D000935:Antifungal Agents / Q000737:chemistry; D006801:Humans; D007938:Leukemia / Q000188:drug therapy; D015394:Molecular Structure; D009183:Mycotoxins / Q000737:chemistry* / Q000627:therapeutic use*; D011753:Pyrones / Q000737:chemistry* / Q000627:therapeutic use*; D013329:Structure-Activity Relationship
D000935:Antifungal Agents; D009183:Mycotoxins; D011753:Pyrones; C011890:kojic acid