HLA-A2 and B35 are strong predictors of responsiveness to clozapine: preliminary data in Italian schizophrenia patients.
Marchini
M
M
Scorza
R
R
Antonioli
R
R
Scarone
S
S
Grassi
B
B
Epifani
M
M
Dragoni
C
C
D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003024:Clozapine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D015789:HLA-A2 Antigen / Q000378:metabolism*; D015797:HLA-B35 Antigen / Q000378:metabolism*; D006801:Humans; D007558:Italy; D008297:Male; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism*; D012680:Sensitivity and Specificity; D016896:Treatment Outcome
D014150:Antipsychotic Agents; D015789:HLA-A2 Antigen; D015797:HLA-B35 Antigen; D003024:Clozapine