title: Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens.
authors.affiliation: Wyeth-Ayerst Research, Chemical Sciences, 145 King of Prussia Road, Radnor, Pennsylvania 19087, USA. milerc1@war.wyeth.com
authors.forename: C P
authors.initials: CP
authors.lastname: Miller
authors.forename: M D
authors.initials: MD
authors.lastname: Collini
authors.forename: B D
authors.initials: BD
authors.lastname: Tran
authors.forename: H A
authors.initials: HA
authors.lastname: Harris
authors.forename: Y P
authors.initials: YP
authors.lastname: Kharode
authors.forename: J T
authors.initials: JT
authors.lastname: Marzolf
authors.forename: R A
authors.initials: RA
authors.lastname: Moran
authors.forename: R A
authors.initials: RA
authors.lastname: Henderson
authors.forename: R H
authors.initials: RH
authors.lastname: Bender
authors.forename: R J
authors.initials: RJ
authors.lastname: Unwalla
authors.forename: L M
authors.initials: LM
authors.lastname: Greenberger
authors.forename: J P
authors.initials: JP
authors.lastname: Yardley
authors.forename: M A
authors.initials: MA
authors.lastname: Abou-Gharbia
authors.forename: C R
authors.initials: CR
authors.lastname: Lyttle
authors.forename: B S
authors.initials: BS
authors.lastname: Komm
mesh_terms: D000818:Animals; D015519:Bone Density / Q000187:drug effects; D002460:Cell Line; D045166:Estradiol Congeners / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D005260:Female; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D008958:Models, Molecular; D009929:Organ Size; D010052:Ovariectomy; D011869:Radioligand Assay; D051381:Rats; D013329:Structure-Activity Relationship; D014162:Transfection; D014599:Uterus / Q000187:drug effects
chemical_list: D045166:Estradiol Congeners; D007211:Indoles