title: High-frequency recovery of quinupristin-dalfopristin-resistant Enterococcus faecium isolates from the poultry production environment.
abstract: The occurrence of resistance to the streptogramin quinupristin-dalfopristin in Enterococcus faecium isolates from chickens on the Eastern Seaboard, was evaluated. Quinupristin-dalfopristin resistance was found in 51 to 78% of E. faecium isolates from the food production environment. The high level of resistance in this organism suggests that this reservoir of resistance may compromise the therapeutic potential of quinupristin-dalfopristin.
authors.affiliation: Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Hayes
authors.forename: A C
authors.initials: AC
authors.lastname: McIntosh
authors.forename: S
authors.initials: S
authors.lastname: Qaiyumi
authors.forename: J A
authors.initials: JA
authors.lastname: Johnson
authors.forename: L L
authors.initials: LL
authors.lastname: English
authors.forename: L E
authors.initials: LE
authors.lastname: Carr
authors.forename: D D
authors.initials: DD
authors.lastname: Wagner
authors.forename: S W
authors.initials: SW
authors.lastname: Joseph
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D002645:Chickens / Q000382:microbiology*; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination / Q000494:pharmacology*; D016984:Enterococcus faecium / Q000187:drug effects* / Q000302:isolation & purification; D004783:Environmental Microbiology; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology; D014769:Virginiamycin / Q000494:pharmacology*
chemical_list: D014769:Virginiamycin; C062940:quinupristin-dalfopristin