title: The system VO2+ +oxidized glutathione: a potentiometric and spectroscopic study.
abstract: The equilibria in the system VO2+ +oxidized glutathione in aqueous solution have been studied in the pH range 2-11 by a combination of pH potentiometry and spectroscopy (EPR, visible absorption and circular dichroism). The results of the various methods are self-consistent and the equilibrium model includes the species MLH4, MLH3, MLH2, MLH, ML, MLH(-1), MLH(-2) and several hydrolysis products (where H4L denotes oxidized glutathione); individual formation constants and spectra are given. Plausible structures for each stoichiometry are discussed.
authors.affiliation: Centro Química Estrutural, Instituto Superior Técnico, Lisboa, Portugal. pcjpessoa@popsrv.ist.utl.pt
authors.forename: J C
authors.initials: JC
authors.lastname: Pessoa
authors.forename: I
authors.initials: I
authors.lastname: Tomaz
authors.forename: T
authors.initials: T
authors.lastname: Kiss
authors.forename: P
authors.initials: P
authors.lastname: Buglyó
mesh_terms: D002942:Circular Dichroism; D004563:Electrochemistry; D004578:Electron Spin Resonance Spectroscopy; D005978:Glutathione / Q000737:chemistry* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D008024:Ligands; D015394:Molecular Structure; D010084:Oxidation-Reduction / Q000187:drug effects; D014638:Vanadates / Q000737:chemistry*
chemical_list: D008024:Ligands; D014638:Vanadates; D005978:Glutathione