title: Clinical studies of enteritis caused by methicillin-resistant Staphylococcus aureus.
abstract: OBJECTIVE
  To study the clinical features of methicillin-resistant Staphylococcus aureus (MRSA) enteritis in our surgical ward.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Teaching hospital, Japan.
  
  
  METHODS
  16 men and 1 woman who developed MRSA enteritis from January 1995 to October 1999.
  
  
  METHODS
  Causes and treatments.
  
  
  RESULTS
  The underlying diseases were as follows: gastric cancer (n = 13), colorectal cancer (n = 2), recurrent cancer (n = 1) and bowel obstruction following gastrectomy (n = 1). 16 patients were operated on. Two cases were treated with histamine H2 receptor blockers. The mean age of patients was 65 years (range 50-80). In 13 cases MRSA enteritis developed within 6 days of operation. 10 strains of MRSA were isolated from stools, 8 from gastric juice, and 3 from intra-abdominal exudate. 10 patients were treated with vancomycin given through a nasogastric tube and 2 through a nasogastric tube and by drip intravenous infusion. 15 patients survived and 2 died.
  
  
  CONCLUSIONS
  Patients who are given broad-spectrum antibiotics and whose gastric secretion is reduced are at high risk of MRSA enteritis. In the surgical ward, early diagnosis, treatment, and isolation are essential for patients with MRSA enteritis.
authors.affiliation: The Department of Surgery, Tone Chuo Hospital, Numata-city, Gunma, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Takeuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Tsuzuki
authors.forename: T
authors.initials: T
authors.lastname: Ando
authors.forename: M
authors.initials: M
authors.lastname: Sekihara
authors.forename: T
authors.initials: T
authors.lastname: Hara
authors.forename: M
authors.initials: M
authors.lastname: Yoshikawa
authors.forename: M
authors.initials: M
authors.lastname: Kudo
authors.forename: H
authors.initials: H
authors.lastname: Kuwano
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology; D004751:Enteritis / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D005743:Gastrectomy; D006784:Hospitals, Teaching; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D016106:Methicillin Resistance; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology / Q000382:microbiology*; D012004:Rectal Neoplasms / Q000150:complications / Q000601:surgery; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects; D013274:Stomach Neoplasms / Q000601:surgery