title: Skin involvement as the first manifestation of systemic aspergillosis in patients after allogeneic hematopoietic cell transplantation.
abstract: Skin involvement due to a systemic infection with Aspergillus species in the course of allogeneic hematopoietic cell transplantation is extremely rare. We report the clinical course of two patients with hematologic malignancies who underwent allogeneic hematopoietic cell transplantation (HCT) and developed disseminated skin involvement as the first clinical symptom of a proven systemic Aspergillus infection.
authors.affiliation: Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus an der TU Dresden, Fetscher Str. 74, 01307 Dresden, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Schimmelpfennig
authors.forename: R
authors.initials: R
authors.lastname: Naumann
authors.forename: T
authors.initials: T
authors.lastname: Zuberbier
authors.forename: R
authors.initials: R
authors.lastname: Ordemann
authors.forename: H
authors.initials: H
authors.lastname: Baurmann
authors.forename: J
authors.initials: J
authors.lastname: Beyer
authors.forename: W
authors.initials: W
authors.lastname: Siegert
authors.forename: M
authors.initials: M
authors.lastname: Bornhäuser
authors.forename: G
authors.initials: G
authors.lastname: Ehninger
mesh_terms: D000328:Adult; D001228:Aspergillosis / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D017809:Fatal Outcome; D019337:Hematologic Neoplasms / Q000150:complications / Q000628:therapy; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D016867:Immunocompromised Host / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D012871:Skin Diseases / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D014184:Transplantation, Homologous / Q000009:adverse effects