Acute disseminated encephalomyelitis in autoimmune hemolytic anemia.
A 16-year-old female with chronic autoimmune hemolytic anemia is presented. She was diagnosed with acute disseminated encephalomyelitis by clinical findings and magnetic resonance imaging (MRI), and the condition occurred after a systemic infection with Cryptococcus neoformans. Intravenous immunoglobulin therapy remarkably improved the patient's neurologic deficit and resolved abnormalities evidenced on MRI. To our knowledge, this report is the first of a pediatric patient with autoimmune hemolytic anemia complicated by acute disseminated encephalomyelitis that developed after an apparently successful treatment of cryptococcal meningitis.
Jaing
T H
TH
Divisions of Hematology and Oncology, Chang Gung Children's Hospital, Taoyuan, Taiwan.
Lin
K L
KL
Chiu
C H
CH
Lo
W C
WC
Wu
P L
PL
D000293:Adolescent; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications*; D001921:Brain / Q000473:pathology; D002908:Chronic Disease; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging; D016919:Meningitis, Cryptococcal / Q000188:drug therapy* / Q000382:microbiology; D016896:Treatment Outcome
D016756:Immunoglobulins, Intravenous