[Study on the replacement of the portal vein of pig with autogeneous-peritoneal tube].
OBJECTIVE
To investigate the possibility of applying autogeneous peritoneal tube in the portal vein reconstruction.


METHODS
Twenty-seven small healthy domestic pigs were used. A section of portal vein about 2.5-3.0 cm long was resected and replaced by autogenous peritoneum tube (APT), autogenous vein and decron artificial blood vessel respectively. Patency and pathological changes of the APT grafts were investigated after the replacement.


RESULTS
Twenty-four animals survived the operation. In the early stage of replacement, the APTs were dilated slightly, the cannual patency rate (CPR) was 12/13(92.3%). 3 months later, the fibrous hypertrophy and thickness were observed. The CPR was 8/10(80%). 2 more months later, the CPR was 4/6(66.7%), which was quite similar to that reconstructed by autogeneous vein. All three pigs which were replaced by decron blood vessel were dead within three to five hours after operation because of portal thrombi found by autopsy. After 12 weeks of replacement, scanning electron microscopy revealed that APT grafts were covered with a layer of endothelial-like cells. Endothelial cells and mesothelial cells were seen under transmitted electronic microscopy.


CONCLUSIONS
The long-term patency of the APTs were slightly lower than that of the autogenous vein, peritoneum might be a perspective self-material for portal vein reconstruction and worth further studying.
Chen
W
W
Second Affilicated Hospital of Sun Yat-sen University of Medical Sciences, Guangzhou 510120.
Ou
Q
Q
Xiao
M
M
D000818:Animals; D001807:Blood Vessel Prosthesis; D005260:Female; D008297:Male; D010537:Peritoneum / Q000637:transplantation*; D011091:Polyesters; D011169:Portal Vein / Q000293:injuries / Q000601:surgery*; D011897:Random Allocation; D013552:Swine; D014182:Transplantation, Autologous; D016042:Transplantation, Heterotopic; D014680:Veins / Q000637:transplantation
D011091:Polyesters