title: Lesions of the inferior alveolar nerve arising from endodontic treatment.
abstract: A lesion of the IAN following endodontic treatment of the lower molars and premolars is not a rare event and presents an uncomfortable situation both for the dental surgeon and the patient. Injury can result on the one hand by direct intrusion of the instrument through the apex into the mandibular canal, and on the other by the filling material which becomes forced into the mandibular canal. In the latter case, a nerve lesion will only result when the filling material contains neurotoxic substances such as paraformaldehyde. With a direct lesion or when forcing of resorbable filling material into the mandibular canal is suspected, one should first employ a wait-and-see approach, because usually the only nerve damage is in the form of neuropraxy or axonotmesis for which there is a high rate of spontaneous regeneration. However, if neurotoxic filling material is introduced into the direct vicinity of the nerves, the mandibular canal should be opened and the filling material should be removed as early as possible. If the filling material is forced directly within the endoneurium between the nerve bundles, the damaged nerve sections must be resected and bridged using transplants from the sural or greater auricular nerves.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Medical University of Hannover, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. MKG-Chirurgie@mh-hannover.de
authors.forename: R
authors.initials: R
authors.lastname: Dempf
authors.forename: J E
authors.initials: JE
authors.lastname: Hausamen
mesh_terms: D000328:Adult; D001641:Bicuspid; D003389:Cranial Nerve Diseases / Q000139:chemically induced / Q000209:etiology* / Q000601:surgery / Q000628:therapy; D005260:Female; D006801:Humans; D006987:Hypesthesia / Q000139:chemically induced; D008297:Male; D008340:Mandibular Nerve / Q000187:drug effects / Q000601:surgery; D008875:Middle Aged; D008963:Molar; D009408:Nerve Compression Syndromes / Q000209:etiology; D012183:Retrograde Degeneration; D012387:Root Canal Filling Materials / Q000009:adverse effects; D012390:Root Canal Therapy / Q000009:adverse effects* / Q000295:instrumentation; D013497:Sural Nerve / Q000637:transplantation; D061221:Trigeminal Nerve Injuries
chemical_list: D012387:Root Canal Filling Materials