[RGS and the regulation of G protein signal transduction].
Regulators of G-protein signaling (RGSs) are recently identified negative regulator of G-protein signaling, most of the RGSs act as GTPase activating proteins (GAPs). RGSs can selectively act on Gas and their effects are scrupulously regulated in vivo. It is believed that we can learn more about regulation of signal transduction from the development of research on RGSs.
Chen
X Y
XY
Molecular Biology Center, Research Institute of Surgery and DaPing Hospital, Third Military Medical University, Chongqing 400042.
Zhou
Y G
YG
D020558:GTP Phosphohydrolases / Q000378:metabolism; D019204:GTP-Binding Proteins / Q000502:physiology*; D006160:Guanosine Triphosphate / Q000378:metabolism; D015394:Molecular Structure; D015221:Potassium Channels / Q000502:physiology; D020710:RGS Proteins / Q000737:chemistry / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*
D015221:Potassium Channels; D020710:RGS Proteins; D006160:Guanosine Triphosphate; D020558:GTP Phosphohydrolases; D019204:GTP-Binding Proteins