title: [Seroprevalence of Chagas disease in Ushuaia, Argentina, an area without Triatominae].
abstract: OBJECTIVE
  Determine the seroprevalence of Trypanosoma cruzi infection in Ushuaia, Argentina, which is the southernmost city in the world.
  
  
  METHODS
  Serum samples were analyzed from 2,991 people, obtained between January 1995 and December 1996. The samples were processed using indirect hemagglutination and either enzyme-linked immunosorbent assay or indirect immunofluorescence.
  
  
  RESULTS
  The general seroprevalence of T. cruzi infection was 6.8%. According to the residents' country of origin, prevalence was 41.1% among Bolivians, 5.0% among Argentines, and 0.9% among Chileans. The prevalence found in pregnant women was 5.9%; in compulsory examinations (such as for a job or for immigrants settling permanently in Argentina), it was 6.3%; and in examinations done based on clinical or epidemiological reasons to suspect infection with Chagas' disease, it was 30.8%.
  
  
  CONCLUSIONS
  There is an alarming level of T. cruzi infection in this region, where the insect vector does not even exist. Given the risk of transmission congenitally and from blood transfusions, controls must be maintained on donated blood. In addition, follow-up of children of infected women should be strengthened so that these children receive early diagnosis and timely treatment of the infection.
authors.affiliation: Servicio de Laboratorio, Hospital Regional Ushuaia, 12 de octubre y Maipú, 9410 Ushuaia, Tierra del Fuego, Argentina. cmallimaci@infovia.com.ar
authors.forename: M C
authors.initials: MC
authors.lastname: Mallimaci
authors.forename: C
authors.initials: C
authors.lastname: Sijvarger
authors.forename: A
authors.initials: A
authors.lastname: Dates
authors.forename: M
authors.initials: M
authors.lastname: Alvarez
authors.forename: S
authors.initials: S
authors.lastname: Sosa-Estani
mesh_terms: D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis*; D001118:Argentina / Q000453:epidemiology; D001838:Bolivia / Q000453:epidemiology; D014355:Chagas Disease / Q000453:epidemiology* / Q000517:prevention & control; D002648:Child; D002677:Chile / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004641:Emigration and Immigration; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006386:Hemagglutination Tests; D006801:Humans; D008297:Male; D011247:Pregnancy; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D065227:Transfusion Reaction; D014225:Triatominae; D014349:Trypanosoma cruzi / Q000276:immunology*
chemical_list: D000913:Antibodies, Protozoan