title: [Hematologic aspects of inflammatory bowel diseases].
abstract: Anaemia, thrombocytosis are common secondary changes in inflammatory bowel disease (IBD), reflecting the clinical severity of the IBD cases, too. On the other hand, increased platelet function, fibrinolytic abnormalities, hypercoagulation of IBD patients predispose to thromboembolic events, and they may as well contribute to the local microcirculatory alterations leading to IBD itself. Reduced FXIII levels have been observed in IBD, which seems to be correlated with mucosal repair and might have therapeutic importance, too. Genetic thrombophilia received much attention recently, however, much less is known how frequent they are in IBD, what their clinical significance is, do they modify the clinical course itself. A short, concise review about links between haematology and IBD is given.
authors.affiliation: Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, II. Belgyógyászati Klinika.
authors.forename: M
authors.initials: M
authors.lastname: Udvardy
authors.forename: I
authors.initials: I
authors.lastname: Altorjay
authors.forename: K
authors.initials: K
authors.lastname: Palatka
mesh_terms: D001777:Blood Coagulation / Q000235:genetics; D001778:Blood Coagulation Disorders / Q000097:blood* / Q000150:complications* / Q000235:genetics; D003093:Colitis, Ulcerative / Q000097:blood; D003424:Crohn Disease / Q000097:blood; D005165:Factor V / Q000235:genetics; D005176:Factor XIII / Q000378:metabolism; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000097:blood* / Q000150:complications* / Q000235:genetics; D009154:Mutation; D013923:Thromboembolism / Q000209:etiology; D019851:Thrombophilia / Q000150:complications
chemical_list: D005165:Factor V; D005176:Factor XIII