Large artery vasculitis following recombinant hepatitis B vaccination: 2 cases.
We describe 2 women who developed large artery vasculitis shortly after receiving recombinant hepatitis B vaccination. One patient developed Takayasu's arteritis, the other a vasculitis involving subclavian and renal arteries. Both developed renal failure. Whether the vasculitis was caused by the vaccination is not known. Although small vessel vasculitis following hepatitis B vaccination has been reported a number of times, large vessel vasculitis associated with hepatitis B vaccination has been reported only once. These cases suggest that large artery vasculitis should be added to the list of possible side effects of hepatitis B vaccination.
Zaas
A
A
Department of Medicine, Johns Hopkins Hospital, and the Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Scheel
P
P
Venbrux
A
A
Hellmann
D B
DB
D000328:Adult; D015901:Angiography, Digital Subtraction; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control; D017325:Hepatitis B Vaccines / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging / Q000209:etiology*; D013348:Subclavian Artery; D013625:Takayasu Arteritis / Q000000981:diagnostic imaging / Q000209:etiology*; D014614:Vaccines, Synthetic / Q000009:adverse effects
D017325:Hepatitis B Vaccines; D014614:Vaccines, Synthetic