title: Structural characterization of flavonoid glycosides by collisionally activated dissociation of metal complexes.
abstract: Collisionally activated dissociation is used for structural characterization of a series of flavonoid glycosides. Dissociation of transition metal/flavonoid binary complexes of the type [MII(L - H+)]+ and transition metal/2,2'-bipyridine/flavonoid ternary complexes of the type [MII(L - H+)bpy]+ give fragmentation patterns that are complementary and more diagnostic than those of the protonated, deprotonated, or sodium-cationized flavonoids. Analysis of fragmentation patterns of the [MII(L - H+)bpy]- complexes permits determination of the disaccharide as a rutinose or neohesperidose and the relative placement of the disaccharide (i.e., 3 vs. 7 positions).
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas at Austin, 78712, USA.
authors.forename: M
authors.initials: M
authors.lastname: Satterfield
authors.forename: J S
authors.initials: JS
authors.lastname: Brodbelt
mesh_terms: D015082:2,2'-Dipyridyl / Q000737:chemistry; D003035:Cobalt / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D004187:Disaccharides / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry*; D013058:Mass Spectrometry; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013329:Structure-Activity Relationship
chemical_list: D004187:Disaccharides; D005419:Flavonoids; D009942:Organometallic Compounds; D003035:Cobalt; D015082:2,2'-Dipyridyl; D003300:Copper