title: Coexistence of lung cancer and hamartoma.
abstract: We present a rare case of a synchronous primary lung cancer adjacent to a hamartoma. A 71-year-old woman was admitted with congestive heart failure due to acute myocardial infarction. A chest radiogram on admission showed pulmonary edema with a tumor shadow in the right upper lung field. Because histological diagnosis was not obtained preoperatively, a wedge resection of the lung was conducted using video-assisted thoracoscopic surgery. The histopathological examination confirmed the coexistence of an adenocarcinoma with a chondromatous hamartoma. Right upper lobectomy was performed followed by excision of the mediastinal lymph nodes. Although hamartoma is generally considered to be a benign neoplasm, there have been several reports of increased risk to lung cancer in patients with a chondromatous hamartoma. Therefore, we recommend that patients with a hamartoma should be submitted to a complete evaluation and to regular follow-up, considering the risk to associated synchronous malignancy.
authors.affiliation: Department of Cardiovascular Surgery, Tokyo Women's Medical University Daini Hospital, 2-1-10 Nishi-Ogu, Arakawa-ku, Tokyo 116-8567, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Higashita
authors.forename: S
authors.initials: S
authors.lastname: Ichikawa
authors.forename: T
authors.initials: T
authors.lastname: Ban
authors.forename: Y
authors.initials: Y
authors.lastname: Suda
authors.forename: K
authors.initials: K
authors.lastname: Hayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Takeuchi
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D000328:Adult; D005260:Female; D006222:Hamartoma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D020775:Thoracic Surgery, Video-Assisted