Cellular aspects of Burkholderia cepacia infection.
The Gram-negative bacterium Burkholderia cepacia has recently emerged as an important opportunistic pathogen in humans. This review focuses on the cellular aspects of B. cepacia infection and the dynamics of the B. cepacia-host cell interaction, including recent advances in our understanding of the ability of B. cepacia to adhere to, enter, and survive intracellularly within human cells.
Mohr
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CD
Department of Microbiology, University of Minnesota Medical School, Minneapolis Minnesota, 55455-0312, USA. mohr@lenti.med.umn.edu
Tomich
M
M
Herfst
C A
CA
D019121:Burkholderia Infections / Q000209:etiology; D016956:Burkholderia cepacia / Q000145:classification / Q000235:genetics / Q000472:pathogenicity* / Q000648:ultrastructure; D004847:Epithelial Cells / Q000382:microbiology / Q000648:ultrastructure; D006801:Humans; D008264:Macrophages / Q000382:microbiology / Q000648:ultrastructure; D008854:Microscopy, Electron; D009894:Opportunistic Infections / Q000382:microbiology; D012141:Respiratory Tract Infections / Q000209:etiology; D014774:Virulence