title: The intrinsic origin of nitric oxide synthase immunoreactive nerve fibers in the right atrium of the guinea pig.
abstract: We previously reported three kinds of nitric oxide synthase-immunoreactive (NOS-ir) axons in the guinea pig heart: the sparse fiber network covering the right atrium, the basket-like endings around intracardiac neurons, and the axons in the septal region. The sparse NOS-ir nerve fiber network in the right atrium remained after vagotomy and has been suggested to be originated from intrinsic cardiac ganglia. Using Chorera toxin B as a retrograde tracer, we determined a part of them were derived from cardiac ganglionic neurons located in the area near the vena cavae.
authors.affiliation: Department of Anatomy, Hyogo College of Medicine, Mukogawa, Nishinomiya, 663-8501, Hyogo, Japan. cello@hyo-med.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: A
authors.initials: A
authors.lastname: Takanaga
authors.forename: T
authors.initials: T
authors.lastname: Hayakawa
authors.forename: S
authors.initials: S
authors.lastname: Maeda
authors.forename: M
authors.initials: M
authors.lastname: Seki
mesh_terms: D000818:Animals; D002772:Cholera Toxin; D005260:Female; D005724:Ganglia / Q000201:enzymology; D006168:Guinea Pigs; D006325:Heart Atria; D006329:Heart Conduction System / Q000201:enzymology*; D007150:Immunohistochemistry; D009412:Nerve Fibers / Q000201:enzymology*; D009415:Nerve Net / Q000201:enzymology; D019001:Nitric Oxide Synthase / Q000378:metabolism*; D014628:Vagotomy
chemical_list: D002772:Cholera Toxin; D019001:Nitric Oxide Synthase