title: Enteric viruses associated with HIV infection in Tanzanian children with chronic diarrhea.
abstract: OBJECTIVE
  To determine whether specific viruses are associated with HIV infection in Tanzanian children with chronic diarrhea.
  
  
  METHODS
  Cross-sectional survey.
  
  
  METHODS
  Major national teaching hospital in Dar es Salaam, Tanzania.
  
  
  METHODS
  Consecutively admitted, human immunodeficiency virus (HIV)-infected and HIV-uninfected children with chronic diarrhea, and controls without diarrhea, aged 15 months to 5 years.
  
  
  METHODS
  Enteric viruses identified by electron microscopy (EM) of fecal specimens.
  
  
  RESULTS
  Small round structured viruses (SRSV) were more frequent in HIV-infected than HIV-uninfected children with chronic diarrhea (4 of 21 vs 1 of 32, prevalence ratio = 6.09, 90% confidence limits 1.03, 36.14). Rotavirus and coronavirus-like particles (CVLP) were not associated with HIV infection.
  
  
  CONCLUSIONS
  SRSV may be associated with HIV infection in Tanzanian children with chronic diarrhea. Larger, confirmatory studies are needed.
authors.affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Cegielski
authors.forename: A E
authors.initials: AE
authors.lastname: Msengi
authors.forename: S E
authors.initials: SE
authors.lastname: Miller
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000821:virology*; D002908:Chronic Disease; D017934:Coronavirus / Q000302:isolation & purification; D003430:Cross-Sectional Studies; D003967:Diarrhea / Q000150:complications* / Q000821:virology; D005243:Feces / Q000382:microbiology; D005759:Gastroenteritis / Q000150:complications / Q000821:virology; D006801:Humans; D009663:Norwalk virus / Q000302:isolation & purification; D012401:Rotavirus / Q000302:isolation & purification; D013636:Tanzania; D014777:Virus Diseases / Q000150:complications*