title: Large animal models for testing bioartificial liver support systems.
abstract: After development of a flat membrane bioreactor using primary hepatocytes (FMB) further preclinical investigations were necessary. To study safety and efficiency of liver support systems there is a need for a well-defined large animal model.
authors.affiliation: Dep. of General and Transplant Surgery, University Essen, Germany.
authors.forename: N R
authors.initials: NR
authors.lastname: Frühauf
authors.forename: G M
authors.initials: GM
authors.lastname: Kaiser
authors.forename: S A
authors.initials: SA
authors.lastname: Nosser
authors.forename: A
authors.initials: A
authors.lastname: Bader
authors.forename: K J
authors.initials: KJ
authors.lastname: Oldhafer
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D017093:Liver Failure / Q000209:etiology / Q000628:therapy*; D019164:Liver, Artificial