Analysis of cytokine expression in rheumatoid synovium has provided new insights into the pathogenesis of rheumatoid arthritis and new therapeutic opportunities.
Feldmann
M
M
Kennedy Institute of Rheumatology, London, UK.
Brennan
F
F
Bondeson
J
J
Paleolog
E
E
Foxwell
B
B
Maini
R
R
D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000276:immunology*; D002478:Cells, Cultured; D018920:Coculture Techniques; D016207:Cytokines / Q000096:biosynthesis / Q000276:immunology* / Q000494:pharmacology; D015195:Drug Design; D006801:Humans; D019409:Interleukin-15 / Q000494:pharmacology; D007376:Interleukin-2 / Q000494:pharmacology; D015850:Interleukin-6 / Q000494:pharmacology; D008264:Macrophages / Q000187:drug effects / Q000276:immunology*; D013583:Synovial Membrane / Q000276:immunology*; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis / Q000276:immunology* / Q000494:pharmacology
D016207:Cytokines; D019409:Interleukin-15; D007376:Interleukin-2; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha