title: Photochemistry of tosylstilbenoids in the preparation of complex heterocyclic compounds. Synthesis of a cyclopropafuroindolone analogue of the dna-alkylating section of the antitumor compound CC-1065.
abstract: [reaction in text] A novel photocyclization of tosylstilbenoids is used in the preparation of a cyclopropafuroindolone analogue of the DNA-alkylating unit of the antitumor compound CC-1065.
authors.affiliation: Departamento de Química Orgánica y Unidad Asociada al CSIC, Universidad de Santiago de Compostela, 15706 Santiago de Compostela, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Enjo
authors.forename: L
authors.initials: L
authors.lastname: Castedo
authors.forename: G
authors.initials: G
authors.lastname: Tojo
mesh_terms: D018906:Antineoplastic Agents, Alkylating / Q000737:chemistry* / Q000494:pharmacology; D001572:Benzofurans / Q000737:chemistry; D004247:DNA / Q000494:pharmacology; D000080890:Duocarmycins; D005663:Furans / Q000138:chemical synthesis*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis*; D007933:Leucomycins / Q000737:chemistry* / Q000494:pharmacology; D015394:Molecular Structure; D010777:Photochemistry; D013267:Stilbenes / Q000737:chemistry; D013329:Structure-Activity Relationship; D014105:Tosyl Compounds / Q000737:chemistry
chemical_list: D018906:Antineoplastic Agents, Alkylating; D001572:Benzofurans; D000080890:Duocarmycins; D005663:Furans; D006571:Heterocyclic Compounds; D007211:Indoles; D007933:Leucomycins; D013267:Stilbenes; D014105:Tosyl Compounds; C018782:CC 1065; D004247:DNA