[Hydrolysis of various peptides and proteins in weak permanent and low frequency fluctuating magnetic fields].
It was shown that weak combined magnetic fields (constant field 25-130 microT; variable field 0.01-0.2 microT; the range of effective frequencies of the alternating component 1-10 Hz) substantially increase the rate of hydrolysis of some proteins and peptides (eight various sequences). The concentration dependence of the dynamics of the process and the dependence of the magnitude of the effect on the parameters of the magnetic field. It was found that: (1) the effect is transmitted through a solvent preliminarily treated by magnetic fields and (2) the effect occurs in the presence of inhibitors of proteases and enzymes inactivating peroxides (catalase and horse radish peroxidase with substrate).
Novikov
V V
VV
Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290 Russia.
Fesenko
E E
EE
D002851:Chromatography, High Pressure Liquid; D006868:Hydrolysis; D008280:Magnetics; D010455:Peptides / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*; D012996:Solutions
D010455:Peptides; D011506:Proteins; D012996:Solutions