title: MALT lymphoma originating in breast and uvula.
abstract: A case of marginal zone B cell lymphoma of MALT type arising in the uvula and breast is reported. The patient, a 30-year-old woman who delivered a child and lactated in 1997, was suffering from Sjögren syndrome (SS). She was diagnosed with MALT lymphoma after a biopsy of the right breast and uvula. To investigate the relationship of the delivery, lactation and MALT lymphoma, we examined the immunohistochemical analysis of hormone receptors. As a result, lymphoid cells of the breast were stained with anti-progesterone receptor antibodies in the cytoplasm. Consequently, the MALT lymphoma of the uvula appeared to be associated with SS. Moreover, hormones such as progesterone may have influenced the breast involvement of MALT lymphoma in our case.
authors.affiliation: First Department of Internal Medicine, Tokyo Medical University, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Okabe
authors.forename: Y
authors.initials: Y
authors.lastname: Kuriyama
authors.forename: Y
authors.initials: Y
authors.lastname: Kawanishi
authors.forename: N
authors.initials: N
authors.lastname: Yahata
authors.forename: K
authors.initials: K
authors.lastname: Miyazawa
authors.forename: Y
authors.initials: Y
authors.lastname: Kimura
authors.forename: H
authors.initials: H
authors.lastname: Serizawa
authors.forename: Y
authors.initials: Y
authors.lastname: Ebihara
authors.forename: K
authors.initials: K
authors.lastname: Ohyashiki
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000737:chemistry / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007743:Labor, Obstetric / Q000378:metabolism; D007774:Lactation / Q000378:metabolism; D018442:Lymphoma, B-Cell, Marginal Zone / Q000737:chemistry / Q000209:etiology* / Q000473:pathology; D009062:Mouth Neoplasms / Q000209:etiology*; D011247:Pregnancy; D011980:Receptors, Progesterone / Q000378:metabolism; D012859:Sjogren's Syndrome / Q000150:complications; D014609:Uvula
chemical_list: D011980:Receptors, Progesterone