title: Tibial osteonecrosis.
abstract: Spontaneous osteonecrosis of the tibial plateau involves a continuum of change observed in the subchondral zone that is commonly associated with early and mid stages of osteoarthritis. The typical patient is an elderly woman who experiences a sudden onset of pain in the medial aspect of the knee. The diagnosis of this under-appreciated clinical entity may be difficult, but careful examination and judicious use of imaging studies, as well as a high index of suspicion, may facilitate the accurate diagnosis. Although the radiographs may initially be normal (with the exception of mild arthrosis), radionuclide scans and MRI can be of great value. The MRI studies usually show a decreased signal intensity on a T1-weighted image, but may be normal in the early course of the disease. The T2-weighted images and fat suppression views are helpful in establishing a diagnosis and determining the extent of involvement. Recognition of this problem may help to avoid unnecessary intra-articular surgery. Many of these patients have complete or partial resolution of symptoms by 1 year, after a period of protected weight bearing. Nonetheless, surgery may be necessary for more advanced lesions and in those patients with progressive arthrosis.
authors.affiliation: Pennsylvania Orthopaedic Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
authors.forename: J H
authors.initials: JH
authors.lastname: Lonner
authors.forename: P A
authors.initials: PA
authors.lastname: Lotke
mesh_terms: D000328:Adult; D003952:Diagnostic Imaging; D006801:Humans; D007719:Knee Joint / Q000473:pathology*; D010020:Osteonecrosis / Q000175:diagnosis* / Q000209:etiology; D011379:Prognosis; D013977:Tibia / Q000473:pathology*