Gene-environment interplay in oppositional defiant and conduct disorder.
Oppositional defiant and conduct disorder is a disturbance in behavior that is characterized by aggressive and antisocial acts. At present, genetic research on conduct disorder has raised more questions than it has answered, and basic questions such as the heritability of childhood antisocial behavior cannot yet be answered with certainty. Current research, however, has consistently highlighted the importance of gene-environment interplay in antisocial behavior.
Simonoff
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Department of Child and Adolescent Psychiatry, Guy's, King's, and St. Thomas' School of Medicine and Institute of Psychiatry, London, United Kingdom.
D000293:Adolescent; D000987:Antisocial Personality Disorder / Q000175:diagnosis / Q000235:genetics; D019958:Attention Deficit and Disruptive Behavior Disorders / Q000175:diagnosis / Q000235:genetics*; D002648:Child; D002653:Child Behavior Disorders / Q000175:diagnosis / Q000235:genetics*; D015897:Comorbidity; D004200:Diseases in Twins / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D001523:Mental Disorders / Q000175:diagnosis / Q000235:genetics; D012729:Sex Chromosome Aberrations / Q000235:genetics; D012931:Social Environment; D018433:Twin Studies as Topic; D014998:Y Chromosome