title: Composite pituitary adenoma and intrasellar tuberculoma: report of a rare case.
abstract: Tuberculous involvement of the pituitary gland is rare. We report a unique case of a composite lesion consisting of pituitary adenoma and intrasellar tuberculoma. A 24-year-old lady presented with features of acromegaly and amenorrhea. Serum growth hormone levels were found to be raised. Radiological investigations were consistent with a pituitary adenoma. Decompression of the lesion was done through trans-sphenoidal approach. Histological examination revealed a growth hormone secreting pituitary adenoma in association with a granulomatous lesion suggesting of pituitary tuberculoma. No other evidence of tuberculosis was found in the brain or spinal cord. This type of dual pathology has been reported only once in the earlier literature.
authors.affiliation: All India Institute of Medical Sciences, Department of Pathology, New Delhi - 110029, India.
authors.forename: M C
authors.initials: MC
authors.lastname: Sharma
authors.forename: S
authors.initials: S
authors.lastname: Vaish
authors.forename: R
authors.initials: R
authors.lastname: Arora
authors.forename: S
authors.initials: S
authors.lastname: Gaikwad
authors.forename: C
authors.initials: C
authors.lastname: Sarkar
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D010902:Pituitary Gland / Q000000981:diagnostic imaging / Q000473:pathology*; D010911:Pituitary Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D015175:Prolactinoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D016862:Tuberculoma, Intracranial / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology