title: Short report: Hyperammonaemia in critically ill septic infants.
abstract: Three infants with subphrenic abscess, pyonephrosis, and obstructive ureterocoele respectively had grossly increased concentrations of plasma ammonia. This was considered to be a result of infections with urea splitting organisms. All died in spite of intensive care support, including specific measures to reduce plasma ammonia.
authors.affiliation: Royal Hospital for Sick Children, Sciennes Road, Edinburgh EH9 1LF, UK.
authors.forename: P
authors.initials: P
authors.lastname: McEwan
authors.forename: D
authors.initials: D
authors.lastname: Simpson
authors.forename: J M
authors.initials: JM
authors.lastname: Kirk
authors.forename: D G
authors.initials: DG
authors.lastname: Barr
authors.forename: K J
authors.initials: KJ
authors.lastname: McKenzie
mesh_terms: D000641:Ammonia / Q000378:metabolism; D003422:Critical Care; D016638:Critical Illness; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D022124:Hyperammonemia / Q000382:microbiology* / Q000628:therapy; D020925:Hypoxia-Ischemia, Brain / Q000382:microbiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D018805:Sepsis / Q000150:complications* / Q000628:therapy
chemical_list: D000641:Ammonia