Failed treatment of abdominal pregnancy with methotrexate. A case report.
BACKGROUND
Methotrexate is an effective, safe, low-cost alternative to surgery for treating tubal pregnancies. To our knowledge, there have only been two other reported attempts at treating abdominal pregnancy with methotrexate.


METHODS
Despite two courses of treatment with methotrexate, the pregnancy persisted, and laparoscopy permitted a tissue diagnosis of abdominal pregnancy.


CONCLUSIONS
Although treatment with methotrexate was not successful in this case, its potential use in abdominal pregnancies merits further investigation.
Zinger
M
M
Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA. mzinger@usa.net
Rosenfeld
D
D
D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D000328:Adult; D005260:Female; D006801:Humans; D007247:Infertility, Female; D007273:Injections, Intramuscular; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D011269:Pregnancy, Abdominal / Q000188:drug therapy* / Q000601:surgery; D017211:Treatment Failure
D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate