Short report: Hyperammonaemia in critically ill septic infants.
Three infants with subphrenic abscess, pyonephrosis, and obstructive ureterocoele respectively had grossly increased concentrations of plasma ammonia. This was considered to be a result of infections with urea splitting organisms. All died in spite of intensive care support, including specific measures to reduce plasma ammonia.
McEwan
P
P
Royal Hospital for Sick Children, Sciennes Road, Edinburgh EH9 1LF, UK.
Simpson
D
D
Kirk
J M
JM
Barr
D G
DG
McKenzie
K J
KJ
D000641:Ammonia / Q000378:metabolism; D003422:Critical Care; D016638:Critical Illness; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D022124:Hyperammonemia / Q000382:microbiology* / Q000628:therapy; D020925:Hypoxia-Ischemia, Brain / Q000382:microbiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D018805:Sepsis / Q000150:complications* / Q000628:therapy
D000641:Ammonia