Wartenberg's migrant sensory neuritis.
We describe a patient with the sudden onset of a painful, purely sensory, mononeuritis multiplex. Investigations showed no evidence for any underlying systemic condition. A nerve biopsy showed fascicular wallerian degeneration with perineurial thickening, inflammatory cells, and immunoglobulin G (IgG) deposition. His painful sensory deficits persisted, with no improvement after treatment with prednisone. The clinical characteristics in this case were very similar to those originally described by Wartenberg, and subsequently by other investigators. The investigations in our case strongly suggest that there may be an underlying immune pathogenesis for cases of Wartenberg's migrant sensory neuritis.
Nicolle
M W
MW
Departments of Clinical Neurological Sciences, London Health Sciences Centre, 339 Windermere Road, London, Ontario N6A 5A5, Canada. mnicolle@julian.uwo.ca
Barron
J R
JR
Watson
B V
BV
Hammond
R R
RR
Miller
T A
TA
D000328:Adult; D001706:Biopsy; D001917:Brachial Plexus / Q000473:pathology / Q000648:ultrastructure; D020968:Brachial Plexus Neuritis / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D009443:Neuritis / Q000276:immunology / Q000473:pathology*; D010525:Peripheral Nerves / Q000473:pathology