title: Health-related quality of life in patients with laryngeal cancer: a post-treatment comparison of different modes of communication.
abstract: BACKGROUND
  The effects of different treatment modalities and voice and speech rehabilitation methods on the quality of life in patients with laryngeal cancer are not fully understood.
  
  
  METHODS
  A cross-sectional post-treatment questionnaire survey of 125 patients with laryngeal cancer was performed. The response rate was 74%. Three patient groups were identified: patients treated with radiotherapy and communicating with preserved larynx (n = 70), laryngectomized patients using a tracheoesophageal prosthesis (TEP) for speech (n = 14), and laryngectomized patients communicating with an electrolarynx (n = 5). Two established generic questionnaires, the Sickness Impact Profile (SIP) and the Hospital Anxiety and Depression (HAD) scale, were used.
  
  
  RESULTS
  The radiotherapy and the TEP groups displayed similar SIP and HAD profiles. No significant differences were seen in favor of the radiotherapy group, whereas the TEP group reported fewer problems in the SIP sleep/rest subscale. In 10 of 12 SIP categories, the numerically highest proportion of patients with clinically important dysfunction (SIP scores >10) was found in the small electrolarynx group.
  
  
  CONCLUSIONS
  Successful speech rehabilitation with a TEP after laryngectomy may be as effective as conservative treatment with radiotherapy for laryngeal cancer with regard to psychosocial adjustment and functional ability, as measured with generic quality of life instruments.
authors.affiliation: Department of Otorhinolaryngology, Sahlgrenska University Hospital, S-431 80 Mölndal, Sweden. Caterina.Finizia@orlss.gu.se
authors.forename: C
authors.initials: C
authors.lastname: Finizia
authors.forename: B
authors.initials: B
authors.lastname: Bergman
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000523:psychology* / Q000532:radiotherapy / Q000534:rehabilitation*; D007825:Laryngectomy; D008297:Male; D008347:Manifest Anxiety Scale; D008875:Middle Aged; D011788:Quality of Life; D018434:Sickness Impact Profile; D013071:Speech, Alaryngeal; D013072:Speech, Esophageal; D011795:Surveys and Questionnaires