The role of radiotherapy and limb-conserving surgery in the management of soft-tissue sarcomas in adults.
The treatment of soft-tissue sarcomas has undergone significant changes over the past several decades. Previously, patients were often treated with surgery alone, which frequently necessitated amputation of the affected extremity. Less extensive, limb-sparing operations combined with adjuvant irradiation are now feasible for most patients without compromising the likelihood of cure.
Parsons
J T
JT
Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida, USA.
Zlotecki
R A
RA
Reddy
K A
KA
Mitchell
T P
TP
Marcus
R B
RB
Scarborough
M T
MT
D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology / Q000601:surgery; D012509:Sarcoma / Q000532:radiotherapy* / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000532:radiotherapy* / Q000601:surgery*