Does (CUG)n repeat in DMPK mRNA 'paint' chromosome 19 to suppress distant genes to create the diverse phenotype of myotonic dystrophy?: A new hypothesis of long-range cis autosomal inactivation.
Junghans
R P
RP
Harvard Institute of Human Genetics, Harvard Medical School, Division of Hematology/Oncology, HIM Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. junghans@hms.harvard.edu
Ebralidze
A
A
Tiwari
B
B
D020413:3' Untranslated Regions / Q000235:genetics; D000818:Animals; D002874:Chromosome Mapping; D020223:Chromosome Painting; D002888:Chromosomes, Human, Pair 19; D005786:Gene Expression Regulation; D006801:Humans; D008957:Models, Genetic; D009223:Myotonic Dystrophy / Q000235:genetics* / Q000503:physiopathology; D065636:Myotonin-Protein Kinase; D010641:Phenotype; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics*; D013489:Suppression, Genetic; D018911:Trinucleotide Repeats
D020413:3' Untranslated Regions; C585517:DMPK protein, human; D012333:RNA, Messenger; D065636:Myotonin-Protein Kinase; D017346:Protein Serine-Threonine Kinases