A perspective on inflammatory bowel disease in the child and adolescent at the turn of the millennium.
The literature of the past year has produced significant advances relevant to the diagnosis and treatment of children and adolescents with inflammatory bowel disease. This review focuses on new observations regarding the epidemiology, genetics, etiology, diagnosis, and treatment of both Crohn's disease and ulcerative colitis in children. Particular attention is paid to the expanded indications for the use of immunomodulatory therapy, and to the early published data regarding the safety and efficacy of treatment with infliximab.
Haller
C
C
Division of Pediatric Gastroenterology and Nutrition, North Shore University Hospital, 300 Community Drive, Manhasset, NY 11030, USA. jamesm@nshs.edu
Markowitz
J
J
D000293:Adolescent; D002648:Child; D002669:Child Welfare; D002675:Child, Preschool; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D013997:Time Factors