title: Postoperative inflammation in a patient with multiple sclerosis.
abstract: We report a 51-year old white woman with a history of relapsing episodes of multiple sclerosis (MS) who developed acute anterior uveitis 11 days after having uneventful phacoemulsification with posterior chamber intraocular lens implantation. Topical corticosteroids relieved the pain and inflammation within hours. A week after the episode of anterior uveitis, the patient had a severe systemic relapse of MS. Acute inflammation in MS patients during the postoperative period may be noninfectious and could be a prodrome for a relapse of MS.
authors.affiliation: University of Utah Health Sciences Center, Department of Ophthalmology and Visual Sciences, Salt Lake City, Utah 84132, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Coombs
authors.forename: F J
authors.initials: FJ
authors.lastname: Durcan
mesh_terms: D000208:Acute Disease; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000009:adverse effects*; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications* / Q000188:drug therapy; D018918:Phacoemulsification / Q000009:adverse effects*; D011239:Prednisolone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D012008:Recurrence; D014606:Uveitis, Anterior / Q000188:drug therapy / Q000209:etiology*
chemical_list: D005938:Glucocorticoids; C009935:prednisolone acetate; D011239:Prednisolone