title: Long-term patency of experimental magnetic compression gastroenteric anastomoses achieved with covered stents.
abstract: BACKGROUND
  Our aim was to evaluate the efficacy of a prototype "YO-YO"-shaped covered stent for keeping experimental magnetic compression gastroenteric fistulas patent for 6 months.
  
  
  METHODS
  Magnets were introduced perorally with endoscopic and fluoroscopic guidance and were mated across the gastric and jejunal walls of 5 dogs. After a mean of 5.5 days a 12-mm diameter YO-YO stent was placed perorally in the resulting fistula. The gastroenteric anastomosis (GEA) with stent was observed endoscopically and gastrographically at 1- to 2-month intervals.
  
  
  RESULTS
  There was no morbidity and there were no significant weight changes. The GEA was widely patent at necropsy at 6 months (n = 4); partial membrane separation occurred at 5 months in the fifth dog. There was minor breakage of the stent prongs in 2 animals.
  
  
  CONCLUSIONS
  Peroral creation of a stented magnetic compression GEA is safe and provides long-term patency. This technique may be potentially useful for managing gastric outlet obstruction caused by malignancy.
authors.affiliation: Section of Interventional Radiology and the Division of Gastroenterology, Hospital of the University of Pennsylvania, Philladelphia 1904, USA.
authors.forename: C
authors.initials: C
authors.lastname: Cope
authors.forename: G G
authors.initials: GG
authors.lastname: Ginsberg
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D020099:Coated Materials, Biocompatible; D004195:Disease Models, Animal; D004285:Dogs; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005500:Follow-Up Studies; D005747:Gastric Fistula / Q000000981:diagnostic imaging / Q000628:therapy*; D007412:Intestinal Fistula / Q000000981:diagnostic imaging / Q000628:therapy*; D007579:Jejunal Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D008280:Magnetics; D011312:Pressure; D011859:Radiography; D012680:Sensitivity and Specificity; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D020099:Coated Materials, Biocompatible